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Sample records for area specific spectrum

  1. Experiences with area specific spectrum stripping of NaI(Tl) gamma spectra.

    Science.gov (United States)

    Aage, H K; Korsbech, U; Bargholz, K; Bystöm, S; Wedmark, M; Thorshaug, S

    2006-01-01

    Processing of airborne and carborne gamma-ray spectra (AGS and CGS) often includes the stripping (elimination) of the signals from natural radioactivity. Hereby the net result becomes the signals from man-made radioactivity or other radiation anomalies. The parameters needed for spectrum stripping are dependent on detector size and quality as well as on the energy windows. In addition they depend on the environmental geometry including the vehicle carrying the detector. For AGS the altitude also influences the parameters. In general the stripping parameters are determined from tedious laboratory or field measurements with known sources of natural radioactivity. Stripping parameters may, however, often be calculated from the actual survey data or from data from a similar area. Both post-processing and real-time processing are possible. The technique is useful for gamma source search, for detection of radiation anomalies and for mapping of contamination levels. The use of the technique is illustrated with field exercise data.

  2. Area spectrum of slowly rotating black holes

    OpenAIRE

    2010-01-01

    We investigate the area spectrum for rotating black holes which are Kerr and BTZ black holes. For slowly rotating black holes, we use the Maggiore's idea combined with Kunstatter's method to derive their area spectra, which are equally spaced.

  3. On the "Universal" Quantum Area Spectrum

    CERN Document Server

    Medved, A J M

    2009-01-01

    There has been much discourse about the form of the quantum area spectrum for a black hole horizon, with the evenly spaced conception of Bekenstein figuring prominently in the discussions. In this letter, we refine a very recent analysis that supports a proposed universal value for the spacing between adjacent levels in the Bekenstein spectral form. We argue that our refined treatment, although logistically similar to its predecessor, is conceptually more elegant, formally simpler and able to circumvent a couple of technical issues. As an added bonus, our rendition translates very readily to a fully generic theory of gravity.

  4. Area spectrum of the D-dimensional de Sitter spacetime

    Energy Technology Data Exchange (ETDEWEB)

    Lopez-Ortega, A., E-mail: alopezo@ipn.m [Centro de Investigacion en Ciencia Aplicada y Tecnologia Avanzada, Unidad Legaria, Instituto Politecnico Nacional, Calzada Legaria 694 Colonia Irrigacion, Delegacion Miguel Hidalgo, Mexico, D.F., C.P. 11500 (Mexico)

    2009-11-23

    The determination of the quantum area spectrum of a black hole horizon by means of its asymptotic quasinormal frequencies has been explored recently. We believe that for D-dimensional de Sitter horizon we must study if the idea works. Thus taking into account the local description of the thermodynamics of horizons proposed by Padmanabhan and the results of Hod, Kunstatter, and Maggiore we study the area spectrum of the D-dimensional de Sitter horizon.

  5. Spectrum Load Balancing for Flexible Spectrum Usage in Local Area Deployment Scenario

    DEFF Research Database (Denmark)

    Kumar, Sanjay; Wang, Yuanye; Marchetti, Nicola;

    2008-01-01

    In this paper we propose a non-contention based mechanism for allocation of the spectral resources by several interfering Home e-NodeBs (HeNBs) deployed by the same or different operators, potentially in random manner in a given geographical area. The proposed mechanism facilitates allocation...... of spectral resources from a common pool based on the individual traffic requirements of the HeNBs, thereby enabling Flexible Spectrum Usage (FSU). It ensures coexistence of several HeNBs in the given geographical area by partially or completely preventing mutual interference on the shared spectrum...

  6. Technical Considerations in Emerging Medical Body Area Network Spectrum Regulation

    NARCIS (Netherlands)

    Wang, D.; Smith, D.; Ghosh, M.

    2011-01-01

    Medical Body Area Network (MBAN) technology provides a promising solution to improve patient care outcomes and lower healthcare costs. However, the current spectrum allocation cannot cater to increasing MBAN applications. Therefore, U.S., as well as other regions, have already been considering allo

  7. Statistics of black hole radiance and the horizon area spectrum

    CERN Document Server

    Bekenstein, Jacob D

    2015-01-01

    The statistical response of a Kerr black hole to incoming quantum radiation has heretofore been studied by the methods of maximum entropy or quantum field theory in curved spacetime. Neither approach pretends to take into account the quantum structure of the black hole itself. To address this last issue we calculate here the conditional probability distribution associated with the hole's response by assuming that the horizon area has a discrete quantum spectrum, and that its quantum evolution corresponds to jumps between adjacent area eigenvalues, possibly occurring in series, with consequent emission or absorption of quanta, possibly in the same mode. This "atomic" model of the black hole is implemented in two different ways and recovers the previously calculated radiation statistics in both cases. The corresponding conditional probably distribution is here expressed in closed form in terms of an hypergeometric function.

  8. A specific deficit of imitation in autism spectrum disorder.

    Science.gov (United States)

    Stewart, Hannah J; McIntosh, Rob D; Williams, Justin H G

    2013-12-01

    Imitation is a potentially crucial aspect of social cognitive development. Although deficits in imitation ability have been widely demonstrated in autism spectrum disorder (ASD), the specificity and significance of the findings is unclear, due largely to methodological limitations. We developed a novel assessment of imitation ability, using objective movement parameters (path length and action duration) derived from a touch-sensitive tablet laptop during drawing actions on an identical tablet. By direct comparison of the kinematics of a model's actions with those of the participant who observed them, measures of imitation accuracy were obtained. By replaying the end-point of the movement as a spot on the screen, imitation accuracy was compared against a "ghost control" condition, with no human actor but only the end-point of the movement seen [object movement reenactment (OMR)]. Hence, demands of the control task were closely matched to the experimental task with respect to motor, memory, and attentional abilities. Adolescents with ASD showed poorer accuracy for copying object size and action duration on both the imitation and OMR tasks, but were significantly more impaired for imitation of object size. Our results provide evidence that some of the imitation deficit in ASD is specific to a self-other mapping problem, and cannot be explained by general factors such as memory, spatial reasoning, motor control, or attention, nor related to the social demands of the testing situation.

  9. Spectrum of area in the Faddeev formulation of gravity

    CERN Document Server

    Khatsymovsky, V M

    2016-01-01

    Faddeev formulation of general relativity (GR) is considered where the metric is composed of ten vector fields or a ten-dimensional tetrad. Upon partial use of the field equations, this theory results in the usual GR. Earlier we have proposed first-order representation of the minisuperspace model for the Faddeev formulation where the tetrad fields are piecewise constant on the polytopes like 4-simplices or, say, cuboids into which ${\\rm I {-3pt} R}^4$ can be decomposed, an analogue of the Cartan-Weyl connection-type form of the Hilbert-Einstein action in the usual continuum GR. In the Hamiltonian formalism, the tetrad bilinears are canonically conjugate to the orthogonal connection matrices. We evaluate the spectrum of the elementary areas, functions of the tetrad bilinears. The spectrum is discrete and proportional to the Faddeev analog $\\gamma_{\\rm F}$ of the Barbero-Immirzi parameter $\\gamma$. The possibility of the tetrad and metric discontinuities in the Faddeev gravity allows to consider any surface as ...

  10. Face recognition deficits in autism spectrum disorders are both domain specific and process specific.

    Science.gov (United States)

    Weigelt, Sarah; Koldewyn, Kami; Kanwisher, Nancy

    2013-01-01

    Although many studies have reported face identity recognition deficits in autism spectrum disorders (ASD), two fundamental question remains: 1) Is this deficit "process specific" for face memory in particular, or does it extend to perceptual discrimination of faces as well? And 2) Is the deficit "domain specific" for faces, or is it found more generally for other social or even nonsocial stimuli? The answers to these questions are important both for understanding the nature of autism and its developmental etiology, and for understanding the functional architecture of face processing in the typical brain. Here we show that children with ASD are impaired (compared to age and IQ-matched typical children) in face memory, but not face perception, demonstrating process specificity. Further, we find no deficit for either memory or perception of places or cars, indicating domain specificity. Importantly, we further showed deficits in both the perception and memory of bodies, suggesting that the relevant domain of deficit may be social rather than specifically facial. These results provide a more precise characterization of the cognitive phenotype of autism and further indicate a functional dissociation between face memory and face perception.

  11. Area spectrum of the three-dimensional G(o)del black hole

    Institute of Scientific and Technical Information of China (English)

    Li Hui-Ling

    2012-01-01

    The aim of this paper is to investigate the area spectrum of the three-dimensional G(o)del black hole by using two different methods.The result shows that the area spectrum of the black hole is △A =8πl2p,which confirms the initial proposal of Bekenstein that the area spectrum is independent of black hole parameters and the spacing is 8πl2p.

  12. Spectrum

    DEFF Research Database (Denmark)

    Høgfeldt Hansen, Leif

    2016-01-01

    The publication functions as a proces description of the development and construction of an urban furniture SPECTRUM in the city of Gwangju, Republic of Korea. It is used as the cataloque for the exhibition of Spectrum.......The publication functions as a proces description of the development and construction of an urban furniture SPECTRUM in the city of Gwangju, Republic of Korea. It is used as the cataloque for the exhibition of Spectrum....

  13. Pacemaker-Mediated Tachycardia: Manufacturer Specifics and Spectrum of Cases.

    Science.gov (United States)

    Monteil, Benjamin; Ploux, Sylvain; Eschalier, Romain; Ritter, Philippe; Haissaguerre, Michel; Koneru, Jayanthi N; Ellenbogen, Kenneth A; Bordachar, Pierre

    2015-12-01

    Pacemaker-mediated tachycardia (PMT) is the term used to describe a repetitive sequence of sensed retrograde P waves followed by ventricular pacing at or below the maximum tracking rate. The following events can promote atrioventricular (AV) dissociation, retrograde conduction, and the onset of PMT: ventricular or atrial extrasystole, an excessively long programmed AV delay, external interference or myopotentials sensed by the atrial channel, atrial sensing or pacing failure, the absence of postventricular atrial refractory period extension after removal of a magnet, and VDD pacing at a higher rate than sinus rate. In contemporary devices, each manufacturer has a proprietary algorithm to detect and terminate PMT. Because of the increase in the number and complexity of the pacing algorithms and because of manufacturer-driven differences, a basic understanding of these new algorithms is important for patient care. We review here the main elements of the physiopathology of this type of tachycardia, describe the specific characteristics of the different manufacturers, and present representative clinical cases.

  14. Trauma and the psychosis spectrum: A review of symptom specificity and explanatory mechanisms.

    Science.gov (United States)

    Gibson, Lauren E; Alloy, Lauren B; Ellman, Lauren M

    2016-11-01

    Traumatic life events have been robustly associated with various psychosis outcomes, including increased risk of psychotic disorders, the prodrome of psychosis, and dimensional measures of psychotic symptoms, such as attenuated positive psychotic symptoms. However, trauma exposure has been linked to various mental disorders; therefore, the specificity of trauma exposure to psychosis remains unclear. This review focuses on two understudied areas of the trauma and psychosis literature: 1) the specificity between trauma and psychosis in relation to other disorders that often result post-trauma, and 2) proposed mechanisms that uniquely link trauma to psychosis. We begin by discussing the underlying connection between trauma exposure and the entire psychosis spectrum with a focus on the influence of trauma type and specific psychotic symptoms. We then consider how the principles of multifinality and equifinality can be useful in elucidating the trauma-psychosis relationship versus the trauma-other disorder relationship. Next, we discuss several cognitive and neurobiological mechanisms that might uniquely account for the association between trauma and psychosis, as well as the role of gender. Lastly, we review important methodological issues that complicate the research on trauma and psychosis, ending with clinical implications for the field.

  15. Autism Spectrum Disorder in the DSM-5: Diagnostic Sensitivity and Specificity in Early Childhood

    Science.gov (United States)

    Christiansz, Jessica A.; Gray, Kylie M.; Taffe, John; Tonge, Bruce J.

    2016-01-01

    Changes to the DSM-5 Autism Spectrum Disorder (ASD) criteria raised concerns among parents and practitioners that the criteria may exclude some children with Pervasive Developmental Disorder (PDD). Few studies have examined DSM-5 sensitivity and specificity in children less than 5 years of age. This study evaluated 185 children aged 20-55 months…

  16. Sensitivity and Specificity of Proposed DSM-5 Criteria for Autism Spectrum Disorder in Toddlers

    Science.gov (United States)

    Barton, Marianne L.; Robins, Diana L.; Jashar, Dasal; Brennan, Laura; Fein, Deborah

    2013-01-01

    Autism spectrum disorder (ASD) diagnosis is based on behavioral presentation; changes in conceptual models or defining behaviors may significantly impact diagnosis and uptake of ASD-specific interventions. The literature examining impact of DSM-5 criteria is equivocal. Toddlers may be especially vulnerable to the stringent requirements of…

  17. Phonon spectrum of YBCO obtained by specific heat inversion method for real data

    CERN Document Server

    Tao Wen; Dai Xian Xi; Dai Ji Xin; Evenson, W E

    2003-01-01

    In this paper, the phonon spectrum of YBCO is obtained from experimental specific heat data by an exact inversion formula with a parameter for eliminating divergences. The results can be compared to those of neutron inelastic scattering, which can only be carried out in a few laboratories. Some key points of specific heat-phonon spectrum inversion (SPI) theory and a method of asymptotic behaviour control are discussed. An improved unique existence theorem is presented, and a universal function set for numerical calculation of SPI is calculated with high accuracy, which makes the inversion method applicable and convenient in practice. This is the first time specific heat-phonon SPI has been realized for a concrete system.

  18. Design and Simulation of Spectrum Management Methods for Wireless Local Area Networks

    CERN Document Server

    Konsgen, Andreas

    2010-01-01

    Andreas Konsgen describes two major areas of spectrum management: the coordination of neighbouring networks with overlapping ranges by controlling different transmission parameters and the channel allocation by the base station inside a radio cell using a cross-layer approach. Theoretical analyses and simulations demonstrate the usage of these methods and show the QoS enhancements which can be achieved.

  19. Schizophrenia spectrum disorders show reduced specificity and less positive events in mental time travel

    Directory of Open Access Journals (Sweden)

    Xing-jie Chen

    2016-07-01

    Full Text Available Mental time travel refers to the ability to recall past events and to imagine possible future events. Schizophrenia patients have problems in remembering specific personal experiences in the past and imagining what will happen in the future. This study aimed to examine episodic past and future thinking in schizophrenia spectrum disorders including schizophrenia patients and individuals with schizotypal personality disorder (SPD proneness who are at risk for developing schizophrenia. Thirty-two schizophrenia patients, 30 SPD proneness individuals, and 33 healthy controls participated in the study. The Sentence Completion for Events from the Past Test (SCEPT and the Sentence Completion for Events in the Future Test (SCEFT were used to measure past and future thinking abilities. Results showed that schizophrenia patients showed significantly reduced specificity in recalling past and imagining future events, they generated less proportion of specific and extended events compared to healthy controls. SPD proneness individuals only generated less extended events compared to healthy controls. The reduced specificity was mainly manifested in imagining future events. Both schizophrenia patients and SPD proneness individuals generated less positive events than controls. These results suggest that mental time travel impairments in schizophrenia spectrum disorders and have implications for understanding their cognitive and emotional deficits.

  20. Schizophrenia Spectrum Disorders Show Reduced Specificity and Less Positive Events in Mental Time Travel

    Science.gov (United States)

    Chen, Xing-jie; Liu, Lu-lu; Cui, Ji-fang; Wang, Ya; Chen, An-tao; Li, Feng-hua; Wang, Wei-hong; Zheng, Han-feng; Gan, Ming-yuan; Li, Chun-qiu; Shum, David H. K.; Chan, Raymond C. K.

    2016-01-01

    Mental time travel refers to the ability to recall past events and to imagine possible future events. Schizophrenia (SCZ) patients have problems in remembering specific personal experiences in the past and imagining what will happen in the future. This study aimed to examine episodic past and future thinking in SCZ spectrum disorders including SCZ patients and individuals with schizotypal personality disorder (SPD) proneness who are at risk for developing SCZ. Thirty-two SCZ patients, 30 SPD proneness individuals, and 33 healthy controls participated in the study. The Sentence Completion for Events from the Past Test (SCEPT) and the Sentence Completion for Events in the Future Test were used to measure past and future thinking abilities. Results showed that SCZ patients showed significantly reduced specificity in recalling past and imagining future events, they generated less proportion of specific and extended events compared to healthy controls. SPD proneness individuals only generated less extended events compared to healthy controls. The reduced specificity was mainly manifested in imagining future events. Both SCZ patients and SPD proneness individuals generated less positive events than controls. These results suggest that mental time travel impairments in SCZ spectrum disorders and have implications for understanding their cognitive and emotional deficits. PMID:27507958

  1. Quasinormal modes, Superradiance and Area Spectrum for 2+1 Acoustic Black Holes

    CERN Document Server

    Lepe, S; Lepe, Samuel; Saavedra, Joel

    2005-01-01

    We present an exact expression for the quasinormal modes of acoustic disturbances in a rotating 2+1 dimensional sonic black hole (draining bathtub fluid flow) in the low frequency limit and evaluate the adiabatic invariant proposed by Kunstatter. We also compute,via Bohr-Sommerfeld quantization rule the equivalent area spectrum for this acoustic black hole, and we compute the superradiance phenomena for pure spinning 2+1 black holes.

  2. The scaling method of specific catchment area from DEMs

    Institute of Scientific and Technical Information of China (English)

    YANG Xin; TANG Guoan; XlAO Chenchao; GAO Yiping; ZHU Shijie

    2011-01-01

    Specific Catchment Area (SCA) is defined as the upstream catchment area of a unit contour.As one of the key terrain parameters,it is widely used in the modeling of hydrology,soil erosion and ecological environment.However,SCA value changes significantly at different DEM resolutions,which inevitably affect terrain analysis results.SCA can be described as the ratio of Catchment Area (CA) and DEM grid length.In this paper,the scale effect of CA is firstly investigated.With Jiuyuangou Gully,a watershed about 70 km2 in northern Shaanxi Province of China,as the test area,it is found that the impacts of DEM scale on CA are different in spatial distribution.CA value in upslope location becomes bigger with the decrease of the DEM resolution.When the location is close to downstream areas the impact of DEM scale on CA is gradually weakening.The scale effect of CA can be concluded as a mathematic trend of exponential decline.Then,a downscaling model of SCA is put forward by introducing the scale factor and the location factor.The scaling model can realize the conversion of SCA value from a coarse DEM resolution to a finer one at pixel level.Experiment results show that the downscaled SCA was well revised,and consistent with SCA at the target resolution with respect to the statistical indexes,histogram and spatial distribution.With the advantages of no empirical parameters,the scaling model could be considered as a simple and objective model for SCA scaling in a rugged drainage area.

  3. A novel acquisition method of nuclear spectrum based on pulse area analysis

    CERN Document Server

    Dongcang, Li; Lei, Yang; Zhong, Qi; Xiangting, Meng; Bitao, Hu

    2014-01-01

    A novel method based on pulse area analysis(PAA) was presented for acquisition nuclear spectrum by the digitizer. PAA method can be used as a substitute for the traditional method of pulse height analysis (PHA). In the PAA method a commercial digitizer was employed to sample and sum in the pulse, and the area of pulse is proportional to the energy of the detected radiation. The results of simulation and experiment indicate the great advantages of PAA method, especially when the count rate is high and shaping time constant is small. When shaping time constant is 0.5us, the energy resolution of PAA is about 66% better than that of PHA.

  4. Measurement of the cosmic-ray proton spectrum with the Fermi Large Area Telescope

    Science.gov (United States)

    Green, David; Fermi LAT Area Telescope Collaboration Collaboration

    2017-01-01

    We present the measurement of the cosmic-ray proton spectrum between 54 GeV and 9.5 TeV using 7 years of Pass 8 flight data from the Fermi Large Area Telescope (LAT). We developed a dedicated proton event selection with an acceptance of 0.25 m2 sr. Our analysis yields a large dataset with low statistical uncertainty and low residual contamination for a spectral measurement. The systematic errors associated with the acceptance, energy measurement, GEANT4 Monte-Carlo simulations are an order of magnitude larger than the statistical uncertainty. The event selection and spectral measurement of the proton analysis create the opportunity for additional proton analyses with the LAT, such as a dedicated proton anisotropy search.

  5. Area and Entropy Spectrum of Gauss-Bonnet Gravity in de Sitter Space-Times for Black Hole Event Horizon

    Institute of Scientific and Technical Information of China (English)

    CHEN Qiang; REN Ji-Rong

    2013-01-01

    In this paper,we use the modified Hod's treatment and the Kunstatter's method to study the horizon area spectrum and entropy spectrum in Gauss-Bonnet de-Sitter space-time,which is regarded as the natural generalization of Einstein gravity by including higher derivative correction terms to the original Einstein-Hilbert action.The horizon areas have some properties that are very different from the vacuum solutions obtained from the frame of Einstein gravity.With the new physical interpretation of quasinormal modes,the area/entropy spectrum for the event horizon for nearextremal Gauss-Bonnet de Sitter black holes are obtained.Meanwhile,we also extend the discussion of area/entropy quantization to the non-extremal black holes solutions.

  6. Statistical Learning in Specific Language Impairment and Autism Spectrum Disorder: A Meta-Analysis.

    Science.gov (United States)

    Obeid, Rita; Brooks, Patricia J; Powers, Kasey L; Gillespie-Lynch, Kristen; Lum, Jarrad A G

    2016-01-01

    Impairments in statistical learning might be a common deficit among individuals with Specific Language Impairment (SLI) and Autism Spectrum Disorder (ASD). Using meta-analysis, we examined statistical learning in SLI (14 studies, 15 comparisons) and ASD (13 studies, 20 comparisons) to evaluate this hypothesis. Effect sizes were examined as a function of diagnosis across multiple statistical learning tasks (Serial Reaction Time, Contextual Cueing, Artificial Grammar Learning, Speech Stream, Observational Learning, and Probabilistic Classification). Individuals with SLI showed deficits in statistical learning relative to age-matched controls. In contrast, statistical learning was intact in individuals with ASD relative to controls. Effect sizes did not vary as a function of task modality or participant age. Our findings inform debates about overlapping social-communicative difficulties in children with SLI and ASD by suggesting distinct underlying mechanisms. In line with the procedural deficit hypothesis (Ullman and Pierpont, 2005), impaired statistical learning may account for phonological and syntactic difficulties associated with SLI. In contrast, impaired statistical learning fails to account for the social-pragmatic difficulties associated with ASD.

  7. Statistical Learning in Specific Language Impairment and Autism Spectrum Disorder: A Meta-Analysis

    Directory of Open Access Journals (Sweden)

    Rita Obeid

    2016-08-01

    Full Text Available Impairments in statistical learning might be a common deficit among individuals with Specific Language Impairment (SLI and Autism Spectrum Disorder (ASD. Using meta-analysis, we examined statistical learning in SLI (14 studies, 15 comparisons and ASD (13 studies, 20 comparisons to evaluate this hypothesis. Effect sizes were examined as a function of diagnosis across multiple statistical learning tasks (Serial Reaction Time, Contextual Cueing, Artificial Grammar Learning, Speech Stream, Observational Learning, Probabilistic Classification. Individuals with SLI showed deficits in statistical learning relative to age-matched controls g = .47, 95% CI [.28, .66], p < .001. In contrast, statistical learning was intact in individuals with ASD relative to controls, g = –.13, 95% CI [–.34, .08], p = .22. Effect sizes did not vary as a function of task modality or participant age. Our findings inform debates about overlapping social-communicative difficulties in children with SLI and ASD by suggesting distinct underlying mechanisms. In line with the procedural deficit hypothesis (Ullman & Pierpont, 2005, impaired statistical learning may account for phonological and syntactic difficulties associated with SLI. In contrast, impaired statistical learning fails to account for the social-pragmatic difficulties associated with ASD.

  8. Statistical Learning in Specific Language Impairment and Autism Spectrum Disorder: A Meta-Analysis

    Science.gov (United States)

    Obeid, Rita; Brooks, Patricia J.; Powers, Kasey L.; Gillespie-Lynch, Kristen; Lum, Jarrad A. G.

    2016-01-01

    Impairments in statistical learning might be a common deficit among individuals with Specific Language Impairment (SLI) and Autism Spectrum Disorder (ASD). Using meta-analysis, we examined statistical learning in SLI (14 studies, 15 comparisons) and ASD (13 studies, 20 comparisons) to evaluate this hypothesis. Effect sizes were examined as a function of diagnosis across multiple statistical learning tasks (Serial Reaction Time, Contextual Cueing, Artificial Grammar Learning, Speech Stream, Observational Learning, and Probabilistic Classification). Individuals with SLI showed deficits in statistical learning relative to age-matched controls. In contrast, statistical learning was intact in individuals with ASD relative to controls. Effect sizes did not vary as a function of task modality or participant age. Our findings inform debates about overlapping social-communicative difficulties in children with SLI and ASD by suggesting distinct underlying mechanisms. In line with the procedural deficit hypothesis (Ullman and Pierpont, 2005), impaired statistical learning may account for phonological and syntactic difficulties associated with SLI. In contrast, impaired statistical learning fails to account for the social-pragmatic difficulties associated with ASD. PMID:27602006

  9. Holography, mass area relation and discrete quantum spectrum of black holes

    CERN Document Server

    Lochan, Kinjalk

    2015-01-01

    The quantum genesis of Hawking radiation is a long-standing puzzle in black hole physics. Semi-classically one can argue that the spectrum of radiation emitted by a black hole look very much sparse unlike what is expected from a thermal object. It was demonstrated through a simple quantum model that a quantum black hole will retain a discrete profile, at least in the weak energy regime. However, it was suggested that this discreteness might be an artifact of the simplicity of eigenspectrum of the model considered. Different quantum theories can, in principle, give rise to different complicated spectra and make the radiation from black hole dense enough in transition lines, to make them look continuous in profile. We show that such a hope from a geometry-quantized black hole is not realized as long as large enough black holes are dubbed with holographic relation which tells that the entropy of the black hole can be obtained from the area of the horizon and they have a classical mass area relation. We show that...

  10. Evidence for Shared Deficits in Identifying Emotions from Faces and from Voices in Autism Spectrum Disorders and Specific Language Impairment

    Science.gov (United States)

    Taylor, Lauren J.; Maybery, Murray T.; Grayndler, Luke; Whitehouse, Andrew J. O.

    2015-01-01

    Background: While autism spectrum disorder (ASD) and specific language impairment (SLI) have traditionally been conceptualized as distinct disorders, recent findings indicate that the boundaries between these two conditions are not clear-cut. While considerable research has investigated overlap in the linguistic characteristics of ASD and SLI,…

  11. Tract-Specific Analyses of Diffusion Tensor Imaging Show Widespread White Matter Compromise in Autism Spectrum Disorder

    Science.gov (United States)

    Shukla, Dinesh K.; Keehn, Brandon; Muller, Ralph-Axel

    2011-01-01

    Background: Previous diffusion tensor imaging (DTI) studies have shown white matter compromise in children and adults with autism spectrum disorder (ASD), which may relate to reduced connectivity and impaired function of distributed networks. However, tract-specific evidence remains limited in ASD. We applied tract-based spatial statistics (TBSS)…

  12. Reducing Specific Phobia/Fear in Young People with Autism Spectrum Disorders (ASDs) through a Virtual Reality Environment Intervention

    OpenAIRE

    2014-01-01

    Anxiety is common in children with autism spectrum disorders (ASD), with specific fears and phobias one of the most frequent subtypes. Specific fears and phobias can have a serious impact on young people with ASD and their families. In this study we developed and evaluated a unique treatment combining cognitive behaviour therapy (CBT) with graduated exposure in a virtual reality environment (VRE). Nine verbally fluent boys with an ASD diagnosis and no reported learning disability, aged 7 to 1...

  13. Corpus Callosum Area and Brain Volume in Autism Spectrum Disorder: Quantitative Analysis of Structural MRI from the ABIDE Database

    Science.gov (United States)

    Kucharsky Hiess, R.; Alter, R.; Sojoudi, S.; Ardekani, B. A.; Kuzniecky, R.; Pardoe, H. R.

    2015-01-01

    Reduced corpus callosum area and increased brain volume are two commonly reported findings in autism spectrum disorder (ASD). We investigated these two correlates in ASD and healthy controls using T1-weighted MRI scans from the Autism Brain Imaging Data Exchange (ABIDE). Automated methods were used to segment the corpus callosum and intracranial…

  14. Area spectrum of the d-dimensional Reissner-Nordstroem black hole in the small charge limit

    Energy Technology Data Exchange (ETDEWEB)

    Lopez-Ortega, A, E-mail: alopezo@ipn.mx [Centro de Investigacion en Ciencia Aplicada y TecnologIa Avanzada, Unidad Legaria, Instituto Politecnico Nacional, Calzada Legaria 694, Colonia Irrigacion, Delegacion Miguel Hidalgo, Mexico, D F, C P 11500 (Mexico)

    2011-02-07

    A conjecture by Hod states that for the black hole horizon the spacing of its area spectrum is determined by the asymptotic value of its quasinormal frequencies. Recently to overcome some difficulties, Maggiore proposes some changes to the original Hod's conjecture. Taking into account the modifications proposed by Maggiore we calculate the area quantum of the d-dimensional Reissner-Nordstroem black hole in the small charge limit.

  15. Is Talent in Autism Spectrum Disorders Associated with a Specific Cognitive and Behavioural Phenotype?

    Science.gov (United States)

    Bennett, Emily; Heaton, Pamela

    2012-01-01

    Parents of 125 children, adolescents and young adults with autism spectrum disorders completed a newly developed questionnaire aimed at identifying cognitive and behavioural characteristics associated with savant skills in this group. Factors distinguishing skilled individuals were then further investigated in case studies of three individuals…

  16. Sensitivity and Specificity of Proposed "DSM-5" Diagnostic Criteria for Autism Spectrum Disorder

    Science.gov (United States)

    McPartland, James C.; Reichow, Brian; Volkmar, Fred R.

    2012-01-01

    Objective: This study evaluated the potential impact of proposed "DSM-5" diagnostic criteria for autism spectrum disorder (ASD). Method: The study focused on a sample of 933 participants evaluated during the "DSM-IV" field trial; 657 carried a clinical diagnosis of an ASD, and 276 were diagnosed with a non-autistic disorder. Sensitivity and…

  17. Brief Report: Face-Specific Recognition Deficits in Young Children with Autism Spectrum Disorders

    Science.gov (United States)

    Bradshaw, Jessica; Shic, Frederick; Chawarska, Katarzyna

    2011-01-01

    This study used eyetracking to investigate the ability of young children with autism spectrum disorders (ASD) to recognize social (faces) and nonsocial (simple objects and complex block patterns) stimuli using the visual paired comparison (VPC) paradigm. Typically developing (TD) children showed evidence for recognition of faces and simple…

  18. Manganese Dioxide with High Specific Surface Area for Alkaline Battery

    Institute of Scientific and Technical Information of China (English)

    HUANG You-ju; LIN Yu-li; LI Wei-shan

    2012-01-01

    The authors reported a facile method for the synthesis of manganese dioxide without any template and catalyst at a low-temperature.The prepared sample was characterized with X-ray diffraction(XRD),scanning electron microscopy(SEM),Brunauer-Emmett-Teller(BET) surface analysis,Fourier transform infrared(FTIR) spectrometry,cyclic voltammetry,altemative current(AC) impedance test and battery discharge test.It is found that the prepared sample belongs to α-MnO2 and has a microsphere morphology and a large BET surface area.The electrochemical characterization indicates that the prepared sample displays a larger electrochemical capacitance than the commercial electrolytic manganese dioxides(EMD) in Na2SO4 solution,and exhibits larger discharge capacity than EMD,especially at a high rate discharge condition when it is used as cathode of alkaline Zn/MnO2 battery.

  19. A study of specific features of the electronic spectrum of quantum dots in CdSe semiconductor

    Science.gov (United States)

    Mikhailov, A. I.; Kabanov, V. F.; Gorbachev, I. A.; Glukhovskoi, E. G.

    2016-08-01

    Monolayers of CdSe/CdS/ZnS quantum dots (QDs) formed on the aqueous subphase and transferred to solid substrates by the Langmuir-Blodgett method have been studied. The samples obtained were examined by transmission electron microscopy, atomic-force microscopy, and scanning tunnel microscopy. The structure of the QD monolayer obtained on the substrate was analyzed. Specific features of the electronic spectrum of the quantum objects formed in the samples under study were determined.

  20. Functional Specificity of the Visual Word Form Area: General Activation for Words and Symbols but Specific Network Activation for Words

    Science.gov (United States)

    Reinke, Karen; Fernandes, Myra; Schwindt, Graeme; O'Craven, Kathleen; Grady, Cheryl L.

    2008-01-01

    The functional specificity of the brain region known as the Visual Word Form Area (VWFA) was examined using fMRI. We explored whether this area serves a general role in processing symbolic stimuli, rather than being selective for the processing of words. Brain activity was measured during a visual 1-back task to English words, meaningful symbols…

  1. Best Approximation to a Reversible Process in Black-Hole Physics and the Area Spectrum of Spherical Black Holes

    CERN Document Server

    Hod, S

    1999-01-01

    The assimilation of a quantum (finite size) particle by a Reissner-Nordström black hole inevitably involves an increase in the black-hole surface area. It is shown that this increase can be minimized if one considers the capture of the lightest charged particle in nature. The unavoidable area increase is attributed to two physical reasons: the Heisenberg quantum uncertainty principle and a Schwinger-type charge emission (vacuum polarization). The fundamental lower bound on the area increase is $4 \\hbar$, which is smaller than the value given by Bekenstein for neutral particles. Thus, this process is a better approximation to a reversible process in black-hole physics. The universality of the minimal area increase is a further evidence in favor of a uniformly spaced area spectrum for spherical quantum black holes. Moreover, this universal value is in excellent agreement with the area spacing predicted by Mukhanov and Bekenstein and independently by Hod.

  2. Simulation of Leaf Area Development Based on Dry Matter Partitioning and Specific Leaf Area for Cut Chrysanthemum

    NARCIS (Netherlands)

    Lee, J.H.; Heuvelink, E.

    2003-01-01

    This work aims to predict time courses of leaf area index (LAI) based on dry matter partitioning into the leaves and on specific leaf area of newly formed leaf biomass (SLA(n)) for year-round cut chrysanthemum crops. In five glasshouse experiments, each consisting of several plant densities and plan

  3. Self-organized spectrum chunk selection algorithm for Local Area LTE-Advanced

    DEFF Research Database (Denmark)

    Kumar, Sanjay; Wang, Yuanye; Marchetti, Nicola

    2010-01-01

    This paper presents a self organized spectrum chunk selection algorithm in order to minimize the mutual intercell interference among Home Node Bs (HeNBs), aiming to improve the system throughput performance compared to the existing frequency reuse one scheme. The proposed algorithm is useful...

  4. Educational Specifications for Administrative and Support Areas in School Buildings: Considerations in Planning.

    Science.gov (United States)

    Everett, Ronald E.

    1986-01-01

    Educational specifications should contain the following factors for each activity space: objectives, activities, persons to be accommodated, space requirements, spatial relationships, equipment, and special environmental treatments. A list of specifics for administrative areas and food service areas are representative of decisions that must be…

  5. The specific surface area of methane hydrate formed in different conditions and manners

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    The specific surface area of methane hydrates, formed both in the presence and absence of sodium dodecyl sulfate (SDS) and processed in different manners (stirring, compacting, holding the hydrates at the formation conditions for different periods of time, cooling the hydrates for different periods of time before depressurizing them), was measured under atmospheric pressure and temperatures below ice point. It was found that the specific surface area of hydrate increased with the decreasing temperature. The methane hydrate in the presence of SDS was shown to be of bigger specific surface areas than pure methane hydrates. The experimental results further demonstrated that the manners of forming and processing hydrates affected the specific surface area of hydrate samples. Stirring or compacting made the hydrate become finer and led to a bigger specific surface area.

  6. Biological spectrum and dispersal syndromes in an area of the semi-arid region of north-eastern Brazil

    Directory of Open Access Journals (Sweden)

    Elimar Alves de Lima

    2015-03-01

    Full Text Available The biological spectrum and diaspores dispersal syndromes of the species recorded in a stretch of vegetation in a semi-arid region within the Cariri Environment Protection Area, Boa Vista, Paraíba State (northeast Brazil, are described. Collections were made from fertile specimens, preferentially bearing fruit, over a 15-month period. Life forms and syndromes were determined by field observations using specialized literature. One hundred and sixty-six species, distributed into 123 genera and 41 families, were reported. Abiotic syndromes (autochory and anemochory represented 69.7% of all syndromes identified, whilst 30.3% of the species were classified as zoochory. In the life form spectrum therophytes represented 27.7% of species, followed by small- and medium-sized phanerophytes (23.5% and chamaephytes (22.3%. The occurrence of hemicryptophytes (9%, cryptophytes (0.6% and species that could not be classified according to their life forms was also recorded (16.9%. Results showed that the biological spectrum and the dispersal syndromes are highly relevant to understand the structure and function of this phytocenose, with subsidies for the development of other studies in the semi-arid areas of northeastern Brazil.

  7. Fast analytical approach of application specific dose efficient spectrum selection for diagnostic CT imaging and PET attenuation correction

    Science.gov (United States)

    Rui, Xue; Jin, Yannan; FitzGerald, Paul F.; Wu, Mingye; Alessio, Adam M.; Kinahan, Paul E.; De Man, Bruno

    2016-11-01

    Computed tomography (CT) has been used for a variety of applications, two of which include diagnostic imaging and attenuation correction for PET or SPECT imaging. Ideally, the x-ray tube spectrum should be optimized for the specific application to minimize the patient radiation dose while still providing the necessary information. In this study, we proposed a projection-based analytic approach for the analysis of contrast, noise, and bias. Dose normalized contrast to noise ratio (CNRD), inverse noise normalized by dose (IND) and bias are used as evaluation metrics to determine the optimal x-ray spectrum. Our simulation investigated the dose efficiency of the x-ray spectrum ranging from 40 kVp to 200 kVp. Water cylinders with diameters of 15 cm, 24 cm, and 35 cm were used in the simulation to cover a variety of patient sizes. The effects of electronic noise and pre-patient copper filtration were also evaluated. A customized 24 cm CTDI-like phantom with 13 mm diameter inserts filled with iodine (10 mg ml-1), tantalum (10 mg ml-1), water, and PMMA was measured with both standard (1.5 mGy) and ultra-low (0.2 mGy) dose to verify the simulation results at tube voltages of 80, 100, 120, and 140 kVp. For contrast-enhanced diagnostic imaging, the simulation results indicated that for high dose without filtration, the optimal kVp for water contrast is approximately 100 kVp for a 15 cm water cylinder. However, the 60 kVp spectrum produces the highest CNRD for bone and iodine. The optimal kVp for tantalum has two selections: approximately 50 and 100 kVp. The kVp that maximizes CNRD increases when the object size increases. The trend in the CTDI phantom measurements agrees with the simulation results, which also agrees with previous studies. Copper filtration improved the dose efficiency for water and tantalum, but reduced the iodine and bone dose efficiency in a clinically-relevant range (70-140 kVp). Our study also shows that for CT-based attenuation

  8. Derivation of autism spectrum disorder-specific induced pluripotent stem cells from peripheral blood mononuclear cells.

    Science.gov (United States)

    DeRosa, Brooke A; Van Baaren, Jessica M; Dubey, Gaurav K; Lee, Joycelyn M; Cuccaro, Michael L; Vance, Jeffery M; Pericak-Vance, Margaret A; Dykxhoorn, Derek M

    2012-05-10

    Induced pluripotent stem cells (iPSCs) hold tremendous potential both as a biological tool to uncover the pathophysiology of disease by creating relevant cell models and as a source of stem cells for cell-based therapeutic applications. Typically, iPSCs have been derived by the transgenic overexpression of transcription factors associated with progenitor cell or stem cell function in fibroblasts derived from skin biopsies. However, the need for skin punch biopsies to derive fibroblasts for reprogramming can present a barrier to study participation among certain populations of individuals, including children with autism spectrum disorders (ASDs). In addition, the acquisition of skin punch biopsies in non-clinic settings presents a challenge. One potential mechanism to avoid these limitations would be the use of peripheral blood mononuclear cells (PBMCs) as the source of the cells for reprogramming. In this article we describe, for the first time, the derivation of iPSC lines from PBMCs isolated from the whole blood of autistic children, and their subsequent differentiation in GABAergic neurons.

  9. Identification of neuromotor deficits common to autism spectrum disorder and attention deficit/hyperactivity disorder, and imitation deficits specific to autism spectrum disorder.

    Science.gov (United States)

    Biscaldi, Monica; Rauh, Reinhold; Müller, Cora; Irion, Lisa; Saville, Christopher W N; Schulz, Eberhard; Klein, Christoph

    2015-12-01

    Deficits in motor and imitation abilities are a core finding in autism spectrum disorders (ASD), but impaired motor functions are also found in attention deficit/hyperactivity disorder (ADHD). Given recent theorising about potential aetiological overlap between the two disorders, the present study aimed to assess difficulties in motor performance and imitation of facial movements and meaningless gestures in a sample of 24 ADHD patients, 22 patients with ASD, and 20 typically developing children, matched for age (6-13 years) and similar in IQ (>80). Furthermore, we explored the impact of comorbid ADHD symptoms on motor and imitation performance in the ASD sample and the interrelationships between the two groups of variables in the clinical groups separately. The results show motor dysfunction was common to both disorders, but imitation deficits were specific to ASD. Together with the pattern of interrelated motor and imitation abilities, which we found exclusively in the ASD group, our findings suggest complex phenotypic, and possibly aetiological, relationships between the two neurodevelopmental conditions.

  10. The Spectrum of the Isotropic Diffuse Gamma-Ray Emission Derived From First-Year Fermi Large Area Telescope Data

    Energy Technology Data Exchange (ETDEWEB)

    Abdo, A. A.

    2011-08-19

    We report on the first Fermi Large Area Telescope (LAT) measurements of the so-called 'extra-galactic' diffuse {gamma}-ray emission (EGB). This component of the diffuse {gamma}-ray emission is generally considered to have an isotropic or nearly isotropic distribution on the sky with diverse contributions discussed in the literature. The derivation of the EGB is based on detailed modelling of the bright foreground diffuse Galactic {gamma}-ray emission (DGE), the detected LAT sources and the solar {gamma}-ray emission. We find the spectrum of the EGB is consistent with a power law with differential spectral index {gamma} = 2.41 {+-} 0.05 and intensity, I(> 100 MeV) = (1.03 {+-} 0.17) x 10{sup -5} cm{sup -2} s{sup -1} sr{sup -1}, where the error is systematics dominated. Our EGB spectrum is featureless, less intense, and softer than that derived from EGRET data.

  11. [Infrared Spectrum Analysis of Propolis and Tree Gum Collected from Different Areas].

    Science.gov (United States)

    Luo, Huo-lin; Liu, Xing-xing; Gong, Shang-ji; Guo, Xia-li; Luo, Li-ping

    2015-11-01

    Propolis possesses functions of antibacterial, antiviral, anticancer, and liver protection, and is known as the "purple gold", however, the phenomenon which making and selling of counterfeit are growing in intensity. In order to establish a authenticity and quality of propolis evaluation model, in this paper, forty-one Chinese propolis, one proplis from United States and two tree gums were used for experimental materials. The infrared spectrum collection was performed by Fourier transform infrared spectrometer, and principal component analysis (PCA) was used for data analysis. The result showed that, the intrared spectrum of propolis and tree gum were significantly different. The propolis characteristic peak only appeared in 2500-3500 and 400-1800 cm⁻¹. All propolis had two frequency region of characteristic peaks, 2849.08-2848.53 and 2917.74- 2916.76 cm⁻¹, but tree gum did not have characteristic peak in this region. The characteristic peaks of gum were in 1150-1300 and 1550-1650 cm⁻¹. Differences in these aspects can be used to distinguish propolis and gum, and can be used to identify true and false propolis. We use Qinghai propolis as a standard sample, in 42 samples, the matching degree of other propolis is > 80%. In addition, the result of PCA shows that tree gum and the propolis from different climate zone, or with different colors could be distinguished well. This paper firstly performed analysis on different propolis and gum by infrared spectrum, and a new method, for authenticity and quality of propolis identification, could be developed.

  12. Evidence for gender-specific endophenotypes in high-functioning autism spectrum disorder during empathy.

    Science.gov (United States)

    Schneider, Karla; Regenbogen, Christina; Pauly, Katharina D; Gossen, Anna; Schneider, Daniel A; Mevissen, Lea; Michel, Tanja M; Gur, Ruben C; Habel, Ute; Schneider, Frank

    2013-12-01

    Despite remarkable behavioral gender differences in patients with autism spectrum disorder (ASD), and growing evidence for a diminished male : female ratio for the putative "male disorder" ASD, aspects of gender are not addressed accordingly in ASD research. Our study aims at filling this gap by exploring empathy abilities in a group of 28 patients with high-functioning ASD and 28 gender-, age- and education-matched non-autistic subjects, for the first time by means of functional neuroimaging (fMRI). In an event-related fMRI paradigm, emotional ("E") and neutral ("N") video clips presented actors telling self-related short stories. After each clip, participants were asked to indicate their own emotion and its intensity as well as the emotion and intensity perceived for the actor. Behaviorally, we found significantly less empathic responses in the overall ASD group compared with non-autistic subjects, and inadequate emotion recognition for the neutral clips in the female ASD group compared with healthy women. Neurally, increased activation of the bilateral medial frontal gyrus was found in male patients compared with female patients, a pattern which was not present in the non-autistic group. Additionally, autistic women exhibited decreased activation of midbrain and limbic regions compared with non-autistic women, whereas there was no significant difference within the male group. While we did not find a fundamental empathic deficit in autistic patients, our data propose different ways of processing empathy in autistic men and women, suggesting stronger impairments in cognitive aspects of empathy/theory of mind for men, and alterations of social reciprocity for women.

  13. Specificity of transcranial sonography in parkinson spectrum disorders in comparison to degenerative cognitive syndromes

    Directory of Open Access Journals (Sweden)

    Laučkaitė Kristina

    2012-03-01

    Full Text Available Abstract Background Hyperechogenicity of the substantia nigra (SN+, detected by transcranial sonography (TCS, was reported as a characteristic finding in Parkinson's disease (PD, with high diagnostic accuracy values, when compared mainly to healthy controls or essential tremor (ET group. However, some data is accumulating that the SN + could be detected in other neurodegenerative and even in non-neurodegenerative disorders too. Our aim was to estimate the diagnostic accuracy of TCS, mainly focusing on the specificity point, when applied to a range of the parkinsonian disorders, and comparing to the degenerative cognitive syndromes. Methods A prospective study was carried out at the Hospital of Lithuanian University of Health Sciences from January until September 2011. Initially, a TCS and clinical examination were performed on 258 patients and 76 controls. The General Electric Voluson 730 Expert ultrasound system was used. There were 12.8% of cases excluded with insufficient temporal bones, and 4.3% excluded with an unclear diagnosis. The studied sample consisted of the groups: PD (n = 71, 33.2%, ET (n = 58, 27.1%, PD and ET (n = 10, 4.7%, atypical parkinsonian syndromes (APS (n = 3, 1.4%, hereditary neurodegenerative parkinsonism (HDP (n = 3, 1.4%, secondary parkinsonism (SP (n = 23, 10.8%, mild cognitive impairment (MCI (n = 33, 15.4%, dementia (n = 13, 6.1%, and control (n = 71. Results There were 80.3% of PD patients at stages 1 & 2 according to Hoehn and Yahr. At the cut-off value of 0.20 cm2 of the SN+, the sensitivity for PD was 94.3% and the specificity - 63.3% (ROC analysis, AUC 0.891, in comparison to the rest of the cohort. At the cut-off value of 0.26 cm2, the sensitivity was 90% and the specificity 82.4%. The estimations for the lowest specificity for PD, in comparison to the latter subgroups (at the cut-off values of 0.20 cm2 and 0.26 cm2, respectively were: 0% and 33.3% to APS, 33.3% and 66.7% to HDP, 34.8% and 69.6% to SP, 55

  14. Frequency Spectrum Based Low-Area Low-Power Parallel FIR Filter Design

    Directory of Open Access Journals (Sweden)

    Jin-Gyun Chung

    2002-09-01

    Full Text Available Parallel (or block FIR digital filters can be used either for high-speed or low-power (with reduced supply voltage applications. Traditional parallel filter implementations cause linear increase in the hardware cost with respect to the block size. Recently, an efficient parallel FIR filter implementation technique requiring a less-than linear increase in the hardware cost was proposed. This paper makes two contributions. First, the filter spectrum characteristics are exploited to select the best fast filter structures. Second, a novel block filter quantization algorithm is introduced. Using filter benchmarks, it is shown that the use of the appropriate fast FIR filter structures and the proposed quantization scheme can result in reduction in the number of binary adders up to 20%.

  15. Inferred Cosmic-Ray Spectrum from Fermi Large Area Telescope γ-Ray Observations of Earth’s Limb

    Energy Technology Data Exchange (ETDEWEB)

    Ackermann, M.; et al.

    2014-04-17

    Recent accurate measurements of cosmic-ray (CR) species by ATIC-2, CREAM, and PAMELA reveal an unexpected hardening in the proton and He spectra above a few hundred GeV, a gradual softening of the spectra just below a few hundred GeV, and a harder spectrum of He compared to that of protons. These newly-discovered features may offer a clue to the origin of high-energy CRs. We use the ${\\it Fermi}$ Large Area Telescope observations of the $\\gamma$-ray emission from the Earth's limb for an indirect measurement of the local spectrum of CR protons in the energy range $\\sim 90~$GeV-$6~$TeV (derived from a photon energy range $15~$GeV-$1~$TeV). Our analysis shows that single power law and broken power law spectra fit the data equally well and yield a proton spectrum with index $2.68 \\pm 0.04$ and $2.61 \\pm 0.08$ above $\\sim 200~$GeV, respectively.

  16. Reducing specific phobia/fear in young people with autism spectrum disorders (ASDs through a virtual reality environment intervention.

    Directory of Open Access Journals (Sweden)

    Morag Maskey

    Full Text Available Anxiety is common in children with autism spectrum disorders (ASD, with specific fears and phobias one of the most frequent subtypes. Specific fears and phobias can have a serious impact on young people with ASD and their families. In this study we developed and evaluated a unique treatment combining cognitive behaviour therapy (CBT with graduated exposure in a virtual reality environment (VRE. Nine verbally fluent boys with an ASD diagnosis and no reported learning disability, aged 7 to 13 years old, were recruited. Each had anxiety around a specific situation (e.g. crowded buses or stimulus (e.g. pigeons. An individualised scene was recreated in our 'wrap-around' VRE. In the VRE participants were coached by a psychologist in cognitive and behavioural techniques (e.g. relaxation and breathing exercises while the exposure to the phobia/fear stimulus was gradually increased as the child felt ready. Each child received four 20-30 minute sessions. After participating in the study, eight of the nine children were able to tackle their phobia situation. Four of the participants completely overcame their phobia. Treatment effects were maintained at 12 months. These results provide evidence that CBT with VRE can be a highly effective treatment for specific phobia/fear for some young people with ASD.Controlled-Trials.com ISRCTN58483069.

  17. Properties that influence the specific surface areas of carbon nanotubes and nanofibers.

    Science.gov (United States)

    Birch, M Eileen; Ruda-Eberenz, Toni A; Chai, Ming; Andrews, Ronnee; Hatfield, Randal L

    2013-11-01

    Commercially available carbon nanotubes and nanofibers were analyzed to examine possible relationships between their Brunauer-Emmett-Teller specific surface areas (SSAs) and their physical and chemical properties. Properties found to influence surface area were number of walls/diameter, impurities, and surface functionalization with hydroxyl and carboxyl groups. Characterization by electron microscopy, energy-dispersive X-ray spectrometry, thermogravimetric analysis, and elemental analysis indicates that SSA can provide insight on carbon nanomaterials properties, which can differ vastly depending on synthesis parameters and post-production treatments. In this study, how different properties may influence surface area is discussed. The materials examined have a wide range of surface areas. The measured surface areas differed from product specifications, to varying degrees, and between similar products. Findings emphasize the multiple factors that influence surface area and mark its utility in carbon nanomaterial characterization, a prerequisite to understanding their potential applications and toxicities. Implications for occupational monitoring are discussed.

  18. Temporal voice areas exist in autism spectrum disorder but are dysfunctional for voice identity recognition

    Science.gov (United States)

    Borowiak, Kamila; von Kriegstein, Katharina

    2016-01-01

    The ability to recognise the identity of others is a key requirement for successful communication. Brain regions that respond selectively to voices exist in humans from early infancy on. Currently, it is unclear whether dysfunction of these voice-sensitive regions can explain voice identity recognition impairments. Here, we used two independent functional magnetic resonance imaging studies to investigate voice processing in a population that has been reported to have no voice-sensitive regions: autism spectrum disorder (ASD). Our results refute the earlier report that individuals with ASD have no responses in voice-sensitive regions: Passive listening to vocal, compared to non-vocal, sounds elicited typical responses in voice-sensitive regions in the high-functioning ASD group and controls. In contrast, the ASD group had a dysfunction in voice-sensitive regions during voice identity but not speech recognition in the right posterior superior temporal sulcus/gyrus (STS/STG)—a region implicated in processing complex spectrotemporal voice features and unfamiliar voices. The right anterior STS/STG correlated with voice identity recognition performance in controls but not in the ASD group. The findings suggest that right STS/STG dysfunction is critical for explaining voice recognition impairments in high-functioning ASD and show that ASD is not characterised by a general lack of voice-sensitive responses. PMID:27369067

  19. GJB2 mutation spectrum in deaf population in a typical southeastern area of China

    Institute of Scientific and Technical Information of China (English)

    DAI Pu; YOU Yi-wen; CUI Jing-hong; YU Fei; HAN Bing; KANG Dong-yang; YUAN Hui-jun; HAN Dong-yi

    2006-01-01

    Mutations in GJB2 gene are the most frequently found mutations in patients with nonsyndromic hearing impairment. However, the spectrum and prevalence of mutations in this gene vary among different ethnic groups. In China, 30,000 infants are born with congenital hearing impairment annually. In order to provide appropriate genetic testing and counseling to the families, we investigated the molecular etiology of nonsyndromic deafness in 103 unrelated school children attending Nantong School for the Deaf and Mute in Jiangsu Province, China. The coding exon of the GJB2 gene was PCR amplified and sequenced. Sixty two GJB2 mutant alleles were identified in 35.9% (37/103) of the patients. Twenty five patients carried two pathogenic mutations and 12 patients carried one mutant allele. The 235delC was the most common mutation accounting for 69.4% (43/62) of GJB2 mutant alleles.The GJB2 mutant alleles accounted for 30.1% (62/206) of all chromosomes responsible for nonsyndromic hearing impairment. Testing of the 3 most prevalent deleterious frame shift mutations in this cohort detected 100% of all GJB2 mutant alleles. These results demonstrate that an effective genetic testing of GJB2 gene for patients and families with nonsyndromic hearing impairment is possible.

  20. Experimental validation of a distributed algorithm for dynamic spectrum access in local area networks

    DEFF Research Database (Denmark)

    Tonelli, Oscar; Berardinelli, Gilberto; Tavares, Fernando Menezes Leitão;

    2013-01-01

    Next generation wireless networks aim at a significant improvement of the spectral efficiency in order to meet the dramatic increase in data service demand. In local area scenarios user-deployed base stations are expected to take place, thus making the centralized planning of frequency resources...

  1. [Quantitative analysis of content and spectrum of altered mineral in the oil and gas microseepage area].

    Science.gov (United States)

    Li, Qian-qian; Chen, Xiao-Mei; Liu, Xing; Ni, Guo-Qiang

    2013-12-01

    With the Yulin Prefecture in China as the research area and the mineral compositions and reflectance spectra of 119 samples collected in the research area as research data, the present paper analyzes the correlation between the carbonate content of surface altered minerals caused by oil and gas microseepage and such charactersitic parameters of depth, width of its spectral absorption peak, establishes and evaluates a method for determining carbonate content, and proposes a new method for characterizing the degree of oil and gas microseepage by using the carbonate content. Research results show that this method is not only suitable for characterizing the oil and gas microseepage degree of carbonates, but also suitable for studying the oil and gas micro-seepage degree of other types of altered minerals. Therefore, the method can provide reference for studying oil and gas exploration technology by using spectral information of hyperspectral remote sensing.

  2. Preparation and Characterization of Porous Yttrium Oxide Powders with High Specific Surface Area

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    The porous cubic yttrium oxides with high specific surface area were prepared by the explosive decomposition of yttrium nitrate and its complex formed with methyl salicylate. The specific surface area and properties of powders synthesized at various temperatures were characterized using BET, X-ray diffraction (XRD), infrared spectra (IR), and scanning electron microscopy (SEM). The results indicate that the highest specific surface area is found to be 65.37 m2*g-1 at the calcination temperature of 600 ℃, and then decreases to 20.33 m2*g-1 with the calcination temperature rising from 600 to 900 ℃. The powders show strong surface activity for adsorping water and carbon dioxide in air, which also decreases with the rising calcination temperature. The drop both on the surface area and surface activity of samples at higher temperatures may be due to pore-narrowing(sintering) effects.

  3. Synthesis and characterization of large specific surface area nanostructured amorphous silica materials.

    Science.gov (United States)

    Marquez-Linares, Francisco; Roque-Malherbe, Rolando M A

    2006-04-01

    Large specific surface area materials attract wide attention because of their applications in adsorption, catalysis, and nanotechnology. In the present study, we describe the synthesis and characterization of nanostructured amorphous silica materials. These materials were obtained by means of a modification of the Stobe-Fink-Bohn (SFB) method. The morphology and essential features of the synthesized materials have been studied using an automated surface area and pore size analyzer and scanning electron microscopy. The existence of a micro/mesoporous structure in the obtained materials has been established. It was also found that the obtained particle packing materials show large specific surface area up to 1,600 m2/g. (To our best knowledge, there is no any reported amorphous silica material with such a higher specific surface area.) The obtained materials could be useful in the manufacture of adsorbents, catalyst supports, and other nanotechnological applications.

  4. Overlapping and disease specific aspects of impulsivity in children and adolescents with schizophrenia spectrum disorders or Attention-Deficit/Hyperactivity Disorder

    DEFF Research Database (Denmark)

    Jepsen, Jens Richardt Møllegaard; Rydkjær, Jacob; Fagerlund, Birgitte

    Objectives: To identify disease specific and overlapping aspects of impulsivity in children and adolescents with early-onset schizophrenia spectrum disorders or ADHD. Methods: Motor impulsivity (Stop Signal Task), reflection impulsivity (Information Sampling Task), and trait impulsivity (Barratt...... Impulsiveness Scale) are compared between three groups of children and adolescents between 12 and 17 years of age: patients with early-onset schizophrenia spectrum disorders (N=29), patients with ADHD (N=29), and healthy controls (N=45). Results: Preliminary results: Reflection impulsivity is significantly...

  5. Light spectrum on the quality of fruits of physalis species in subtropical area

    Directory of Open Access Journals (Sweden)

    Daniel Fernandes da Silva

    2016-01-01

    Full Text Available ABSTRACT The aim of this study was to analyze the effect of colored-shade nets on the physicochemical characteristics of physalis in subtropical area. The experimental design was the randomized blocks with a 4 × 5 factorial, being four species of physalis (Physalis peruviana, P. pubescens, P. minima and P. ixocarpa and four net colors (white, blue, red and black, besides the control under full sun. Titratable acidity (TA, pH, vitamin C, soluble solids (SS, SS/TA relation, total phenolics, anthocyanins and antioxidant capacity were evaluated. It was observed that P. peruviana and P. pubescens have more acid fruits, and P. minima shows vitamin C content higher than the other species. In general, fruits of P. peruviana and P. pubescens have better quality when grown in white, blue or black shade net; fruits of P. minima are physicochemically superior when produced under full sun or under white or blue shade net; finally, fruits of P. ixocarpa have low quality when produced under black net.

  6. Correlation between relative growth rate and specific leaf area requires associations of specific leaf area with nitrogen absorption rate of roots.

    Science.gov (United States)

    Osone, Yoko; Ishida, Atsushi; Tateno, Masaki

    2008-07-01

    Close correlations between specific leaf area (SLA) and relative growth rate (RGR) have been reported in many studies. However, theoretically, SLA by itself has small net positive effect on RGR because any increase in SLA inevitably causes a decrease in area-based leaf nitrogen concentration (LNCa), another RGR component. It was hypothesized that, for a correlation between SLA and RGR, SLA needs to be associated with specific nitrogen absorption rate of roots (SAR), which counteracts the negative effect of SLA on LNCa. Five trees and six herbs were grown under optimal conditions and relationships between SAR and RGR components were analyzed using a model based on balanced growth hypothesis. SLA varied 1.9-fold between species. Simulations predicted that, if SAR is not associated with SLA, this variation in SLA would cause a47% decrease in LNCa along the SLA gradient, leading to a marginal net positive effect on RGR. In reality, SAR was positively related to SLA, showing a 3.9-fold variation, which largely compensated for the negative effect of SLA on LNCa. Consequently, LNCa values were almost constant across species and a positive SLA-RGR relationship was achieved. These results highlight the importance of leaf-root interactions in understanding interspecific differences in RGR.

  7. Area-specific migration and recruitment of new neurons in the adult songbird brain

    DEFF Research Database (Denmark)

    Vellema, Michiel; Van der Linden, Annemie; Gahr, Manfred

    2010-01-01

    Neuron recruitment has been implicated in morphological and functional plasticity in the adult brain. Whereas mammals restrict neuron recruitment specifically to two regions of known plasticity, the hippocampus and olfactory bulb, newborn neurons are found throughout the forebrain of adult...... sensitive to plastic changes, such as nucleus higher vocal center (HVC) and area X, recruited similar numbers of new neurons as their surrounding brain tissues, employing no specific directional mechanisms. The distribution pattern in and around HVC could best be described by a random displacement model...... toward the olfactory bulb showed high specificity, similar to the mammalian rostral migratory stream. Thus, different mechanisms appear to organize area-specific neuron recruitment in different recipients of the adult songbird brain, unrelated to global plasticity of brain regions....

  8. Preparation of Zirconia-Ceria Powders with High Specific Surface Area

    Institute of Scientific and Technical Information of China (English)

    Wang Enguo; Mei Fang

    2004-01-01

    Zirconia-ceria mixed oxide powders were prepared by high temperature aging method.The effects of the temperature and the time of aging, cerium content and calcination on powder performance were studied.The result shows that high temperature aging is an efficient way of preparation of ZrO2-CeO2 mixed oxide powders with high specific surface area and good thermal stability, and that addition of a small amount of cerium to hydrous zirconia can promote the preparation of high specific surface area powders.

  9. A process to enhance the specific surface area and capacitance of hydrothermally reduced graphene oxide

    KAUST Repository

    Alazmi, Amira

    2016-08-26

    The impact of post-synthesis processing in reduced graphene oxide materials for supercapacitor electrodes has been analyzed. A comparative study of vacuum, freeze and critical point drying was carried out for hydrothermally reduced graphene oxide demonstrating that the optimization of the specific surface area and preservation of the porous network are critical to maximize its supercapacitance performance. As described below, using a supercritical fluid as the drying medium, unprecedented values of the specific surface area (364 m2 g−1) and supercapacitance (441 F g−1) for this class of materials have been achieved.

  10. Spatial risk for gender-specific adult mortality in an area of southern China

    Directory of Open Access Journals (Sweden)

    Ochiai Rion

    2007-07-01

    Full Text Available Abstract Background Although economic reforms have brought significant benefits, including improved health care to many Chinese people, accessibility to improved care has not been distributed evenly throughout Chinese society. Also, the effects of the uneven distribution of improved healthcare are not clearly understood. Evidence suggests that mortality is an indicator for evaluating accessibility to improved health care services. We constructed spatially smoothed risk maps for gender-specific adult mortality in an area of southern China comprising both urban and rural areas and identified ecological factors of gender-specific mortality across societies. Results The study analyzed the data of the Hechi Prefecture in southern in China. An average of 124,204 people lived in the area during the study period (2002–2004. Individual level data for 2002–2004 were grouped using identical rectangular cells (regular lattice of 0.25 km2. Poisson regression was fitted to the group level data to identify gender-specific ecological factors of adult (ages 15– Conclusion We found a disparity in mortality rates between rural and urban areas in the study area in southern China, especially for adult men. There were also differences in mortality rates between poorer and wealthy populations in both rural and urban areas, which may in part reflect differences in health care quality. Spatial influences upon adult male versus adult female mortality difference underscore the need for more research on gender-related influences on adult mortality in China.

  11. The Professional Development Needs of art Teachers in Five Specific Areas

    Directory of Open Access Journals (Sweden)

    Cigdem Hursen,

    2013-05-01

    Full Text Available This research analyses the professional development needs of art teachers in five specific areas: planning lessons; evaluating teaching; applying techniques and methods; producing materials for teaching and activities and; managing. These five areas are based on essential teaching requirements. With the aim of gathering data, research was conducted in Northern Cyprus in government secondary, high and vocational schools, including the vocational schools affiliated to the Ministry of Education. The participant sample consisted of 18 male and 36 female art teachers. Considering the data gathered in this research, it would appear that, there are a significant number of teachers that are having difficulties in the five areas that this study covers.

  12. Specific surface area effect on adsorption of chlorpyrifos and TCP by soils and modeling

    Science.gov (United States)

    The adsorption of chlorpyrifos and TCP (3,5,6, trichloro-2-pyridinol) was determined in four soils (Mollisol, Inceptisol, Entisol, Alfisol) having different specific surface areas (19–84 m2/g) but rather similar organic matter content (2.4–3.5%). Adsorption isotherms were derived from batch equilibr...

  13. Racial and Socioeconomic Variations in Preadolescent Area-Specific and General Self-esteem

    Science.gov (United States)

    Hare, Bruce R.

    1977-01-01

    Discusses a study of two hundred and ten fifth-grade students, noting indications that children of varying backgrounds differ in their levels of general and area-specific self-esteem across both racial and socioeconomic lines but not significantly by sex. For availability see CS 704 480. (MH)

  14. Numerical Treatment of Two-phase Flow in Porous Media Including Specific Interfacial Area

    KAUST Repository

    El-Amin, Mohamed

    2015-06-01

    In this work, we present a numerical treatment for the model of two-phase flow in porous media including specific interfacial area. For numerical discretization we use the cell-centered finite difference (CCFD) method based on the shifting-matrices method which can reduce the time-consuming operations. A new iterative implicit algorithm has been developed to solve the problem under consideration. All advection and advection-like terms that appear in saturation equation and interfacial area equation are treated using upwind schemes. Selected simulation results such as pc–Sw–awn surface, capillary pressure, saturation and specific interfacial area with various values of model parameters have been introduced. The simulation results show a good agreement with those in the literature using either pore network modeling or Darcy scale modeling.

  15. Multidrug-resistant (MDR) Aeromonas recovered from the metropolitan area of Valencia (Spain): diseases spectrum and prevalence in the environment.

    Science.gov (United States)

    Esteve, C; Alcaide, E; Giménez, M J

    2015-01-01

    Aeromonas infections are rare in Europe and often related to traveller's diarrhoea. A total of 185 Aeromonas isolates from river water, fish and clinical sources, recovered during a 1-year period, were used to investigate the disease spectrum and impact of multidrug-resistant (MDR) strains. They were all identified by biochemical tests and 25% of them were also identified by sequencing of the 16S rRNA gene. The minimum inhibitory concentrations (MICs) of 21 antimicrobials were determined for all isolates by broth microdilution/E-strips methods, and susceptibility was assessed according to the Clinical and Laboratory Standards Institute (CLSI). Strains pathogenicity was determined by using Swiss Webster mice as the animal model. Aeromonas diseases had an incidence of around 20 cases/million inhabitants in the metropolitan area of Valencia (Spain). Acute gastroenteritis in children with no history of travel abroad was the main pathology. These cases were related to A. caviae, A. veronii biovar sobria, A. hydrophila and A. dhakensis. A significant incidence of A. caviae in humans was found, while the other species were equally present in clinical and environmental origins. A. jandaei, A. bestiarum and A. media had mainly an environmental distribution. The prevalence of MDR Aeromonas was maximal in clinical samples, and resistance phenotypes were significantly related to this source. 7.2% of environmental Aeromonas was resistant to at least five drugs; most of them were moderately virulent for mice and, in addition, belonged to clinically significant species. The present study demonstrates a diseases spectrum similar to that reported in tropical countries, and also that pathogenic and heavily MDR Aeromonas are present in environmental reservoirs. MDR Aeromonas from any source analysed were susceptible to aztreonam, netilmicin, cefotaxime, ceftazidime, cefepime and fluoroquinolones.

  16. Multifractal interpolation and spectrum-area fractal modeling of stream sediment geochemical data: Implications for mapping exploration targets

    Science.gov (United States)

    Parsa, Mohammad; Maghsoudi, Abbas; Yousefi, Mahyar; Carranza, Emmanuel John M.

    2017-04-01

    The spectrum-area (S-A) fractal model is a powerful tool for decomposition of complex anomaly patterns of gridded geochemical data. Ordinary moving average interpolation techniques are commonly being used for gridding geochemical data; however, these methods suffer from two major drawbacks of (1) ignoring the locally high values and (2) smoothing the interpolated surface. Multifractal moving average interpolation methods have been developed to overcome the shortcomings of ordinary moving average methods. This study seeks to compare two sets of multifractal and ordinary gridded geochemical data using success rate curves and applies the S-A fractal model to decompose anomalous geochemical patterns. A set of stream sediment geochemical data in Ahar area, NW Iran, was used as a case study. Then, a mineralization-related multi-element geochemical signature was gridded by ordinary and multifractal approaches and considered for further analyses. The S-A fractal method was applied to decompose anomaly and background components of the resultant multi-element geochemical signature. Exploration targets were delimited and further evaluated using two bivariate statistical procedures of Student's t-value and normalized density index. The results revealed that (a) application of multifractal gridded data enhances the predicting ability of geochemical signatures, (b) application of S-A fractal model on multifractal gridded data allows for superior discrimination of geochemical anomalies, and (c) the multi-element geochemical anomalies in the Ahar area related to porphyry-Cu deposits were properly delineated through sequence application of multifractal interpolation and S-A fractal model.

  17. Comparison of a Broad-Based Screen versus Disorder-Specific Screen in Detecting Young Children with an Autism Spectrum Disorder

    Science.gov (United States)

    Wiggins, Lisa D; Piazza, Vivian; Robins, Diana L

    2014-01-01

    The goals of our study were to (a) compare agreement between autism spectrum disorder diagnosis and outcome of the Modified Checklist for Autism in Toddlers and Parents Evaluation of Developmental Status in a sample of toddlers and (b) examine specific concerns noted for toddlers who screened negative on the Modified Checklist for Autism in…

  18. Lexical Processing in School-Age Children with Autism Spectrum Disorder and Children with Specific Language Impairment: The Role of Semantics

    Science.gov (United States)

    Haebig, Eileen; Kaushanskaya, Margarita; Weismer, Susan Ellis

    2015-01-01

    Children with autism spectrum disorder (ASD) and specific language impairment (SLI) often have immature lexical-semantic knowledge; however, the organization of lexical-semantic knowledge is poorly understood. This study examined lexical processing in school-age children with ASD, SLI, and typical development, who were matched on receptive…

  19. ON THE SPECIFIC AREA OF INHOMOGENEOUS BOOLEAN MODELS. EXISTENCE RESULTS AND APPLICATIONS

    Directory of Open Access Journals (Sweden)

    Elena Villa

    2011-05-01

    Full Text Available The problem of the evaluation of the so-called specific area of a random closed set, in connection with its mean boundary measure, is mentioned in the classical book by Matheron on random closed sets (Matheron, 1975, p. 50; it is still an open problem, in general. We offer here an overview of some recent results concerning the existence of the specific area of inhomogeneous Boolean models, unifying results from geometric measure theory and from stochastic geometry. A discussion of possible applications to image analysis concerning the estimation of the mean surface density of random closed sets, and, in particular, to material science concerning birth-and-growth processes, is also provided.

  20. Preparation and characterization of boron nitride/carbon fiber composite with high specific surface area

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Yan; Fan, Mingwen [Wuhan Univ. (China). Key Laboratory for Oral Biomedical Engineering; Yuan, Songdong; Xiong, Kun; Hu, Kunpeng; Luo, Yi [Hubei Univ. of Technology, Wuhan (China). School of Chemistry and Chemical Engineering; Li, Dong [Hubei Univ. of Technology, Wuhan (China). School of Chemistry and Chemical Engineering; Oxford Univ. (United Kingdom). Chemistry Research Lab.

    2014-06-15

    Boron nitride can be used as a good catalyst carrier because of its high thermal conductivity and chemical stability. However, a high specific surface area of boron nitride is still desirable. In this work, a carbon fiber composite coated with boron nitride villous nano-film was prepared, and was also characterized by means of scanning electron microscopy, high resolution transmission electron microscopy, Fourier transform infrared spectroscopy, and Brunauer-Emmett-Teller analysis. The results indicated that the carbon fibers were covered by uniform villous boron nitride films whose thickness was about 150 - 200 nm. The specific surface area of the boron nitride/carbon fiber composite material was 96 m{sup 2} g{sup -1}, which was markedly improved compared with conventional boron nitride materials. (orig.)

  1. Different Avalanche Behaviors in Different Specific Areas of a System Based on Neural Networks

    Institute of Scientific and Technical Information of China (English)

    ZHAO Xiao-Wei; CHEN Tian-Lun

    2003-01-01

    Based on the standard self-organizing map (SOM) neural network model and an integrate-and-fire mecha-nism, we introduce a kind of coupled map lattice system to investigate scale-invariance behavior in the activity of modelneural populations. We find power-law distribution behavior of avalanche size in our model. But more importantly, wefind there are different avalanche distribution behaviors in different specific areas of our system, which are formed by thetopological learning process of the SOM net.

  2. Geographic structure of adelie penguin populations: overlap in colony-specific foraging areas

    Science.gov (United States)

    Ainley, D.G.; Ribic, C.A.; Ballard, G.; Heath, S.; Gaffney, I.; Karl, B.J.; Barton, K.J.; Wilson, P.R.; Webb, S.

    2004-01-01

    In an investigation of the factors leading to geographic structuring among Ade??lie Penguin (Pygoscelis adeliae) populations, we studied the size and overlap of colony-specific foraging areas within an isolated cluster of colonies. The study area, in the southwestern Ross Sea, included one large and three smaller colonies, ranging in size from 3900 to 135000 nesting pairs, clustered on Ross and Beaufort Islands. We used triangulation of radio signals from transmitters attached to breeding penguins to determine foraging locations and to define colony-specific foraging areas during the chick-provisioning period of four breeding seasons, 1997-2000. Colony populations (nesting pairs) were determined using aerial photography just after egg-laying; reproductive success was estimated by comparing ground counts of chicks fledged to the number of breeding pairs apparent in aerial photos. Foraging-trip duration, meal size, and adult body mass were estimated using RFID (radio frequency identification) tags and an automated reader and weighbridge. Chick growth was assessed by weekly weighing. We related the following variables to colony size: foraging distance, area, and duration; reproductive success; chick meal size and growth rate; and seasonal variation in adult body mass. We found that penguins foraged closest to their respective colonies, particularly at the smaller colonies. However, as the season progressed, foraging distance, duration, and area increased noticeably, especially at the largest colony. The foraging areas of the smaller colonies overlapped broadly, but very little foraging area overlap existed between the large colony and the smaller colonies, even though the foraging area of the large colony was well within range of the smaller colonies. Instead, the foraging areas of the smaller colonies shifted as that of the large colony grew. Colony size was not related to chick meal size, chick growth, or parental body mass. This differed from the year previous to

  3. A specific area of olfactory cortex involved in stress hormone responses to predator odors

    Science.gov (United States)

    Kondoh, Kunio; Lu, Zhonghua; Ye, Xiaolan; Olson, David P.; Lowell, Bradford B.; Buck, Linda B.

    2016-01-01

    Instinctive reactions to danger are critical to the perpetuation of species and are observed throughout the animal kingdom. The scent of predators induces an instinctive fear response in mice that includes behavioral changes as well as a surge in blood stress hormones that mobilizes multiple body systems to escape impending danger1,2. How the olfactory system routes predator signals detected in the nose to achieve these effects is unknown. Here we identify a specific area of the olfactory cortex that induces stress hormone responses to volatile predator odors. Using monosynaptic and polysynaptic viral tracers, we found that multiple olfactory cortical areas transmit signals to hypothalamic CRH (corticotropin releasing hormone) neurons, which control stress hormone levels. However, only one minor cortical area, the amygdalo-piriform transition area (AmPir), contained neurons upstream of CRH neurons that were activated by volatile predator odors. Chemogenetic stimulation of AmPir activated CRH neurons and induced an increase in blood stress hormone, mimicking an instinctive fear response. Moreover, chemogenetic silencing of AmPir markedly reduced the stress hormone response to predator odors without affecting a fear behavior. These findings suggest that AmPir, a small area comprising olfactory cortex, plays a key role in the hormonal component of the instinctive fear response to volatile predator scents. PMID:27001694

  4. A specific area of olfactory cortex involved in stress hormone responses to predator odours.

    Science.gov (United States)

    Kondoh, Kunio; Lu, Zhonghua; Ye, Xiaolan; Olson, David P; Lowell, Bradford B; Buck, Linda B

    2016-04-01

    Instinctive reactions to danger are critical to the perpetuation of species and are observed throughout the animal kingdom. The scent of predators induces an instinctive fear response in mice that includes behavioural changes, as well as a surge in blood stress hormones that mobilizes multiple body systems to escape impending danger. How the olfactory system routes predator signals detected in the nose to achieve these effects is unknown. Here we identify a specific area of the olfactory cortex in mice that induces stress hormone responses to volatile predator odours. Using monosynaptic and polysynaptic viral tracers, we found that multiple olfactory cortical areas transmit signals to hypothalamic corticotropin-releasing hormone (CRH) neurons, which control stress hormone levels. However, only one minor cortical area, the amygdalo-piriform transition area (AmPir), contained neurons upstream of CRH neurons that were activated by volatile predator odours. Chemogenetic stimulation of AmPir activated CRH neurons and induced an increase in blood stress hormones, mimicking an instinctive fear response. Moreover, chemogenetic silencing of AmPir markedly reduced the stress hormone response to predator odours without affecting a fear behaviour. These findings suggest that AmPir, a small area comprising olfactory cortex, plays a key part in the hormonal component of the instinctive fear response to volatile predator scents.

  5. Genes expressed in specific areas of the human fetal cerebral cortex display distinct patterns of evolution.

    Directory of Open Access Journals (Sweden)

    Nelle Lambert

    Full Text Available The developmental mechanisms through which the cerebral cortex increased in size and complexity during primate evolution are essentially unknown. To uncover genetic networks active in the developing cerebral cortex, we combined three-dimensional reconstruction of human fetal brains at midgestation and whole genome expression profiling. This novel approach enabled transcriptional characterization of neurons from accurately defined cortical regions containing presumptive Broca and Wernicke language areas, as well as surrounding associative areas. We identified hundreds of genes displaying differential expression between the two regions, but no significant difference in gene expression between left and right hemispheres. Validation by qRTPCR and in situ hybridization confirmed the robustness of our approach and revealed novel patterns of area- and layer-specific expression throughout the developing cortex. Genes differentially expressed between cortical areas were significantly associated with fast-evolving non-coding sequences harboring human-specific substitutions that could lead to divergence in their repertoires of transcription factor binding sites. Strikingly, while some of these sequences were accelerated in the human lineage only, many others were accelerated in chimpanzee and/or mouse lineages, indicating that genes important for cortical development may be particularly prone to changes in transcriptional regulation across mammals. Genes differentially expressed between cortical regions were also enriched for transcriptional targets of FoxP2, a key gene for the acquisition of language abilities in humans. Our findings point to a subset of genes with a unique combination of cortical areal expression and evolutionary patterns, suggesting that they play important roles in the transcriptional network underlying human-specific neural traits.

  6. Exploring a novel approach to fabricate vanadium carbide encapsulated into carbon nanotube (VC@C) with large specific surface area

    Indian Academy of Sciences (India)

    Yifu Zhang; Juecheng Zhang; Meijuan Fan; Yan’an Long; Yalan Zhong; Xinghai Liu; Chi Huang

    2013-06-01

    A novel approach to the fabrication of vanadium carbide encapsulated into carbon nanotube (VC@C) core-shell structured composite by thermal treatment with the precursor V3O7.H2O@C was developed for the first time. The as-obtained VC@C were characterized by X-ray powder diffraction (XRD), Raman spectrum, energydispersive X-ray spectrometer (EDX), elemental analysis (EA), Fourier transform infrared spectroscopy (FT)–(IR), scanning electron microscopy (SEM), transmission electron microscopy (TEM) and Brunauer–Emmett–Teller (BET). The results showed that VC@C with core-shell structures could be successfully synthesized at 1000 °C for 2 h. The specific surface area, average pore size and measured pore volume of VC@C were 135.46 m2/g, 4.443 nm and 0.180 cm3/g, respectively indicating that the as-obtained VC@C composite could be used as a mesoporous material. Furthermore, thermal behaviour of the as-obtained VC@C composite in air was investigated by thermogravimetric/differential thermal analyser (TG/DTA). The experimental result revealed that the carbon coated on the surface of VC has high activity with O2 in air atmosphere.

  7. How specific is the immune response to malaria in adults living in endemic areas?

    Directory of Open Access Journals (Sweden)

    B.A. Mannan, K. Patel, I. Malhotra, B. Ravindran & Shobhona Sharma

    2003-09-01

    Full Text Available It is documented that people living in malaria endemic areas acquire immunity against malaria afterrepeated infections. Studies involving passive transfer of IgG from immune adults to the nonimmunesubjects have shown that circulating antibodies play an important role, and that immuneadults possess protective antibodies, which susceptible malaria patients do not. Through a differentialimmunoscreen, we have identified several novel cDNA clones, which react exclusively andyet extensively with immune sera samples. Specific antisera raised against the immunoclones inhibitthe growth of parasites in culture. The clones studied so far turn out to be novel conserved Plasmodiumgenes. In order to study the response of sera of adults from malaria endemic areas of Indiaand Africa to these immunogens, we carried out ELISA assays using these immunopeptides, otherP. falciparum specific antigens, peptides, antigens from other infections such as mycobacterial infectionsand other proteins such as BSA. Children from the same areas and normal healthy urbanpeople showed very little activity to each of these categories. A large percentage of adults from endemicareas responded positively to all the malarial immunogens tested. However, the same personsalso showed high response to other antigens and proteins as well. The implications of theseresults are reported in this paper.

  8. Strategy of specification of management areas: rice grain yield as related to soil fertility

    Directory of Open Access Journals (Sweden)

    Flávio Carlos Dalchiavon

    2013-02-01

    Full Text Available It is well-known nowadays that soil variability can influence crop yields. Therefore, to determine specific areas of soil management, we studied the Pearson and spatial correlations of rice grain yield with organic matter content and pH of an Oxisol (Typic Acrustox under no- tillage, in the 2009/10 growing season, in Selvíria, State of Mato Grosso do Sul, in the Brazilian Cerrado (longitude 51º24' 21'' W, latitude 20º20' 56'' S. The upland rice cultivar IAC 202 was used as test plant. A geostatistical grid was installed for soil and plant data collection, with 120 sampling points in an area of 3.0 ha with a homogeneous slope of 0.055 m m-1. The properties rice grain yield and organic matter content, pH and potential acidity and aluminum content were analyzed in the 0-0.10 and 0.10-0.20 m soil layers. Spatially, two specific areas of agricultural land management were discriminated, differing in the value of organic matter and rice grain yield, respectively with fertilization at variable rates in the second zone, a substantial increase in agricultural productivity can be obtained. The organic matter content was confirmed as a good indicator of soil quality, when spatially correlated with rice grain yield.

  9. Characteristics of PAHs adsorbed on street dust and the correlation with specific surface area and TOC.

    Science.gov (United States)

    Wang, Chengkun; Li, Yingxia; Liu, Jingling; Xiang, Li; Shi, Jianghong; Yang, Zhifeng

    2010-10-01

    Street dust was collected from five roads with different traffic volumes in the metropolitan area of Beijing and separated into five size fractions. Concentrations of polycyclic aromatic hydrocarbons (PAHs) adsorbed on street dust in different size ranges and their correlation with specific surface area and total organic carbon (TOC) were investigated. Results show that the concentration of 16-PAHs of sieved samples ranges from 0.27 to 1.30 mg/kg for all the sampling sites. Particles smaller than 40 mum in diameter have the highest 16-PAHs concentration among all of the size ranges for street dust from the four sampling sites with vehicles running on. PAHs with three or four rings account for 68% of the overall 16-PAHs on average. Remarkable positive correlation exists between 16-PAHs concentration and specific surface area with R(2) values from 0.7 to 0.96 for the four sampling sites with vehicles running on. The relationship between the concentration of 16-PAHs and TOC is less clear.

  10. Prevalence and spectrum of helminths in free-ranging African buffaloes (Syncerus caffer in wildlife protected areas, Tanzania

    Directory of Open Access Journals (Sweden)

    Emanuel Senyael Swai

    2013-09-01

    Full Text Available Objective: To determine the prevalence and spectrum of helminths in free-ranging African buffaloes in Tanzania by a cross-sectional study. Methods: Faecal samples (n=1 23 from Arusha National Park and Ngorongoro Crater were examined for helminth eggs using sedimentation and floatation techniques during the period of March to June 2012. Results: Coprological examination revealed that 34.1% (n=42 of the buffaloes excreted nematodes and trematodes eggs and protozoan oocyst in their faces. The pattern of infection was either single or mixed. Single (52.4% and concurrent infections with two, three, four and five parasites were recorded in 19.0%, 11.9%, 14.3% and 2.3% respectively of the cases. The nematode eggs encountered were those of Trichostrongylus sp. (20.3%, Oesophagostomum sp. (7.3%, Strongyle sp. (4.1%, Bunostomum sp. (4.1%, Ostertegia sp. (3.3% and Toxocara sp. (2.4%. The trematode eggs encountered were those of Fasciola sp. (9.8%, Paramphistomum sp. (4.9%, Gastrothylax sp. (1.6%, Ornithobilharzia sp. (0.81% and Fischoederius sp (0.81%. The protozoan oocyst recorded was that of Eimeria sp. (8.1%. Geographical location of buffaloes had significant influence on the prevalence of infection with Trichostrongylus (P=0.046 and Fasciola (P=0.001, and the mean prevalances in Arusha National Park are significantly higher than those in Ngorongoro Crater. Age had significant influence on infection with Fasciola (P=0.036, and juvenile recorded higher levels of infection than sub-adults. Health status, body condition score and sex-wise prevalence of helminths were not significant (P>0.05. Conclusions: This study indicates that helminths species are numerous and highly prevalent in the two protected areas and may be one of the contributing factors to lower buffalo productivity.

  11. Prevalence and spectrum of helminths in free-ranging African buffaloes (Syncerus caffer) in wildlife protected areas, Tanzania

    Institute of Scientific and Technical Information of China (English)

    Emanuel Senyael Swai; Deogratius Mshanga; Robert Fyumagwa; Deogratius Mpanduji; Idrisa Chuma; Sayael Kuya; Ernest Eblate; Zablon Katale; Julius Keyyu

    2013-01-01

    Objective: To determine the prevalence and spectrum of helminths in free-ranging African buffaloes in Tanzania by a cross-sectional study.Methods:Faecal samples (n=123) from Arusha National Park and Ngorongoro Crater were examined for helminth eggs using sedimentation and floatation techniques during the period of March to June 2012. Results: Coprological examination revealed that 34.1% (n=42) of the buffaloes excreted nematodes and trematodes eggs and protozoan oocyst in their faces. The pattern of infection was either single or mixed. Single (52.4%) and concurrent infections with two, three, four and five parasites were recorded in 19.0%, 11.9%, 14.3% and 2.3% respectively of the cases. The nematode eggs encountered were those of Trichostrongylus sp. (20.3%), Oesophagostomum sp. (7.3%), Strongyle sp. (4.1%), Bunostomum sp. (4.1%), Ostertegia sp. (3.3%) and Toxocara sp. (2.4%). The trematode eggs encountered were those of Fasciola sp. (9.8%), Paramphistomum sp. (4.9%), Gastrothylax sp. (1.6%), Ornithobilharzia sp. (0.81%) and Fischoederius sp (0.81%). The protozoan oocyst recorded was that of Eimeria sp. (8.1%). Geographical location of buffaloes had significant influence on the prevalence of infection with Trichostrongylus (P=0.046) and Fasciola (P=0.001), and the mean prevalances in Arusha National Park are significantly higher than those in Ngorongoro Crater. Age had significant influence on infection with Fasciola (P=0.036), and juvenile recorded higher levels of infection than sub-adults. Health status, body condition score and sex-wise prevalence of helminths were not significant (P>0.05). Conclusions: This study indicates that helminths species are numerous and highly prevalent in the two protected areas and may be one of the contributing factors to lower buffalo productivity.

  12. Reduced Recognition of Dynamic Facial Emotional Expressions and Emotion-Specific Response Bias in Children with an Autism Spectrum Disorder

    Science.gov (United States)

    Evers, Kris; Steyaert, Jean; Noens, Ilse; Wagemans, Johan

    2015-01-01

    Emotion labelling was evaluated in two matched samples of 6-14-year old children with and without an autism spectrum disorder (ASD; N = 45 and N = 50, resp.), using six dynamic facial expressions. The Emotion Recognition Task proved to be valuable demonstrating subtle emotion recognition difficulties in ASD, as we showed a general poorer emotion…

  13. The Autism Mental Status Exam: Sensitivity and Specificity Using DSM-5 Criteria for Autism Spectrum Disorder in Verbally Fluent Adults

    Science.gov (United States)

    Grodberg, David; Weinger, Paige M.; Halpern, Danielle; Parides, Michael; Kolevzon, Alexander; Buxbaum, Joseph D.

    2014-01-01

    The phenotypic heterogeneity of adults suspected of autism spectrum disorder (ASD) requires a standardized diagnostic approach that is feasible in all clinical settings. The autism mental status exam (AMSE) is an eight-item observational assessment that structures the observation and documentation of social, communicative and behavioral signs and…

  14. Age-specific activation of cerebral areas in motor imagery - a fMRI study

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Li [Chongqing University, Key Laboratory of Biorheological Science and Technology of Ministry of Education, Bioengineering College, Chongqing (China); Third Military Medical University, Department of Medical Image, College of Biomedical Engineering, Chongqing (China); Qiu, Mingguo; Zhang, Jingna; Zhang, Ye; Sang, Linqiong [Third Military Medical University, Department of Medical Image, College of Biomedical Engineering, Chongqing (China); Liu, Chen; Yang, Jun [Third Military Medical University, Department of Radiology, Southwest Hospital, Chongqing (China); Yan, Rubing [Third Military Medical University, Department of Rehabilitation, Southwest Hospital, Chongqing (China); Zheng, Xiaolin [Chongqing University, Key Laboratory of Biorheological Science and Technology of Ministry of Education, Bioengineering College, Chongqing (China)

    2014-04-15

    The objectives of this study were to study the age-specific activation patterns of cerebral areas during motor execution (ME) and motor imaging (MI) of the upper extremities and to discuss the age-related neural mechanisms associated with ME or MI. The functional magnetic resonance imaging technique was used to monitor the pattern and intensity of brain activation during the ME and MI of the upper extremities in 20 elderly (>50 years) and 19 young healthy subjects (<25 years). No major differences were identified regarding the activated brain areas during ME or MI between the two groups; however, a minor difference was noted. The intensity of the activated brain area during ME was stronger in the older group than in the younger group, while the results with MI were the opposite. The posterior central gyrus and supplementary motor area during MI were more active in the younger group than in the older group. The putamen, lingual, and so on demonstrated stronger activation during dominant hand MI in the older group. The results of this study revealed that the brain structure was altered and that neuronal activity was attenuated with age, and the cerebral cortex and subcortical tissues were found to be over-activated to achieve the same level of ME and MI, indicating that the activating effects of the left hemisphere enhanced with age, whereas the inhibitory effects declined during ME, and activation of the right hemisphere became more difficult during MI. (orig.)

  15. Different Avalanche Behaviors in Different Specific Areas of a System Based on Neural Networks

    Institute of Scientific and Technical Information of China (English)

    ZHAOXiao-Wei; CHENTian-Lun

    2003-01-01

    Based on the standard self-organizing map (SOM) neural network model and an integrate-and-fire mecha-nism, we introduce a kind of coupled map lattice system to investigate scale-invariance behavior in the activity of model neural populations. We find power-law distribution behavior of avalanche size in our model. But more importantly, we find there are different avalanche distribution behaviors in different specific areas of our system, which are formed by the topological learning process of the SOM net.

  16. Measurement of Specific Surface Area of Ceramisite Made from River Sediment

    Institute of Scientific and Technical Information of China (English)

    LIU Gui-yun; XI Dan-li

    2002-01-01

    Principle and method of measuring Specific Surface Area (SSA) of ceramisite made from dredged river sediment,sewage sludge and adherent materials are discussed.Brunauer-Fmmett- Teller Procedure tests SSA of the ceramisite. Influences of sewage sludge content,adherent content and sintering point on the SSA of ceramisite made of river sediment are also analyzed.Results show that with the right sewage sludge content,adherent content and sintering point, the ceramisite can have the highest SSA value and be widely used.

  17. Nitrogen-doped porous carbon with an ultrahigh specific surface area for superior performance supercapacitors

    Science.gov (United States)

    Long, Chao; Zhuang, Jianle; Xiao, Yong; Zheng, Mingtao; Hu, Hang; Dong, Hanwu; Lei, Bingfu; Zhang, Haoran; Liu, Yingliang

    2016-04-01

    Owing to its abundant nitrogen content, silk cocoon is a promising precursor for the synthesis of Nitrogen-doped porous carbon (N-PC). Using a simple staged KOH activation, the prepared sample displays particular nanostructure with ultrahigh specific surface area (3841 m2 g-1) and appropriate pore size, providing favorable pathways for transportation and penetration of electrolyte ions. Additionally, the doped nitrogen atoms ensure the samples with pseudocapacitive behavior. Those special characteristics endow N-PCs with high capacity, low resistance, and long-term stability, indicating a wonderful potential for application in energy-storage devices.

  18. Combining Amplitude Spectrum Area with Previous Shock Information Using Neural Networks Improves Prediction Performance of Defibrillation Outcome for Subsequent Shocks in Out-Of-Hospital Cardiac Arrest Patients.

    Directory of Open Access Journals (Sweden)

    Mi He

    Full Text Available Quantitative ventricular fibrillation (VF waveform analysis is a potentially powerful tool to optimize defibrillation. However, whether combining VF features with additional attributes that related to the previous shock could enhance the prediction performance for subsequent shocks is still uncertain.A total of 528 defibrillation shocks from 199 patients experienced out-of-hospital cardiac arrest were analyzed in this study. VF waveform was quantified using amplitude spectrum area (AMSA from defibrillator's ECG recordings prior to each shock. Combinations of AMSA with previous shock index (PSI or/and change of AMSA (ΔAMSA between successive shocks were exercised through a training dataset including 255shocks from 99patientswith neural networks. Performance of the combination methods were compared with AMSA based single feature prediction by area under receiver operating characteristic curve(AUC, sensitivity, positive predictive value (PPV, negative predictive value (NPV and prediction accuracy (PA through a validation dataset that was consisted of 273 shocks from 100patients.A total of61 (61.0% patients required subsequent shocks (N = 173 in the validation dataset. Combining AMSA with PSI and ΔAMSA obtained highest AUC (0.904 vs. 0.819, p<0.001 among different combination approaches for subsequent shocks. Sensitivity (76.5% vs. 35.3%, p<0.001, NPV (90.2% vs. 76.9%, p = 0.007 and PA (86.1% vs. 74.0%, p = 0.005were greatly improved compared with AMSA based single feature prediction with a threshold of 90% specificity.In this retrospective study, combining AMSA with previous shock information using neural networks greatly improves prediction performance of defibrillation outcome for subsequent shocks.

  19. Meropenem dosing requirements against Enterobacteriaceae in critically ill patients: influence of renal function, geographical area and presence of extended-spectrum β-lactamases.

    Science.gov (United States)

    Isla, A; Canut, A; Arribas, J; Asín-Prieto, E; Rodríguez-Gascón, A

    2016-03-01

    The aim of this study was the evaluation of the influence of the susceptibility patterns of Escherichia coli and Klebsiella pneumoniae isolates, specifically the presence of extended-spectrum β-lactamases and the geographical area (Europe and USA), on the meropenem dosing requirements in critically ill patients with different degrees of renal function by estimation of the probability of pharmacokinetic/pharmacodynamic (PK/PD) target attainment. Additionally, estimation of the PK/PD breakpoints according to the European Committee on Antimicrobial Susceptibility Testing (EUCAST) approach was also an objective. Six dosing regimens were evaluated: 0.5 g, 1 g and 2 g every 8 h given as 0.5-h or 3-h infusions. Pharmacokinetic data were obtained from the literature, and susceptibility data to meropenem for E. coli and K. pneumoniae were collected from the Tigecycline Evaluation and Surveillance Trial (T.E.S.T.) surveillance study. For the same dose level, the 3-h infusion provided a probability of target attainment (PTA) ≥90 % for minimum inhibitory concentration (MIC) values up to two-fold dilution higher than those obtained with the 0.5-h infusion. For E. coli, the cumulative fraction of response (CFR) was 100 % in most cases, and neither the dose nor the infusion length nor the geographical area significantly affected the probability to reach the target. With regards to K. pneumoniae, the CFR increased when increasing the dose and decreasing the creatinine clearance (CLCR). The CFR for Spanish and USA strains was higher than that calculated for European strains. Meropenem PK/PD breakpoints are dependent on the dose, infusion length and CLCR, ranging from 2 to 32 mg/L. Based on our results, meropenem administered as a extended infusion is the best option to treat infections due to E. coli and K. pneumoniae.

  20. A protected area influences genotype-specific survival and the structure of a Canis hybrid zone.

    Science.gov (United States)

    Benson, John F; Patterson, Brent R; Mahoney, Peter J

    2014-02-01

    It is widely recognized that protected areas can strongly influence ecological systems and that hybridization is an important conservation issue. However, previous studies have not explicitly considered the influence of protected areas on hybridization dynamics. Eastern wolves are a species of special concern and their distribution is largely restricted to a protected population in Algonquin Provincial Park (APP), Ontario, Canada, where they are the numerically dominant canid. We studied intrinsic and extrinsic factors influencing survival and cause-specific mortality of hybrid and parental canids in the three-species hybrid zone between eastern wolves, eastern coyotes, and gray wolves in and adjacent to APP. Mortality risk for eastern wolves in areas adjacent to APP was significantly higher than for other sympatric Canis types outside of APP, and for eastern wolves and other canids within APP. Outside of APP, the annual mortality rate of all canids by harvest (24%) was higher than for other causes of death (4-7%). Furthermore, eastern wolves (hazard ratio = 3.5) and nonresidents (transients and dispersing animals, hazard ratio = 2.7) were more likely to die from harvest relative to other Canis types and residents, respectively. Thus, eastern wolves dispersing from APP were especially vulnerable to harvest mortality. For residents, eastern wolf survival was more negatively influenced by increased road density than for other Canis types, further highlighting the sensitivity of eastern wolves to human disturbance. A cycle of dispersal from APP followed by high rates of mortality and hybridization appears to maintain eastern wolves at low density adjacent to APP, limiting the potential for expansion beyond the protected area. However, high survival and numerical dominance of eastern wolves within APP suggest that protected areas can allow rare hybridizing species to persist even if their demographic performance is compromised and barriers to hybridization are largely

  1. Gender-Associated Differential Expression of Cytokines in Specific Areas of the Brain During Helminth Infection

    Science.gov (United States)

    López-Griego, Lorena; Nava-Castro, Karen Elizabeth; López-Salazar, Valeria; Hernández-Cervantes, Rosalía; Tiempos Guzmán, Nelly; Muñiz-Hernández, Saé; Hernández-Bello, Romel; Besedovsky, Hugo O.; Pavón, Lenin; Becerril Villanueva, Luis Enrique

    2015-01-01

    Intraperitoneal infection with Taenia crassiceps cysticerci in mice alters several behaviors, including sexual, aggressive, and cognitive function. Cytokines and their receptors are produced in the central nervous system (CNS) by specific neural cell lineages under physiological and pathological conditions, regulating such processes as neurotransmission. This study is aimed to determine the expression patterns of cytokines in various areas of the brain in normal and T. crassiceps-infected mice in both genders and correlate them with the pathology of the CNS and parasite counts. IL-4, IFN-γ, and TNF-α levels in the hippocampus and olfactory bulb increased significantly in infected male mice, but IL-6 was downregulated in these regions in female mice. IL-1β expression in the hippocampus was unaffected by infection in either gender. Our novel findings demonstrate a clear gender-associated pattern of cytokine expression in specific areas of the brain in mammals that parasitic infection can alter. Thus, we hypothesize that intraperitoneal infection is sensed by the CNS of the host, wherein cytokines are important messengers in the host–parasite neuroimmunoendocrine network. PMID:25495255

  2. Area-specific development of distinct projection neuron subclasses is regulated by postnatal epigenetic modifications.

    Science.gov (United States)

    Harb, Kawssar; Magrinelli, Elia; Nicolas, Céline S; Lukianets, Nikita; Frangeul, Laura; Pietri, Mariel; Sun, Tao; Sandoz, Guillaume; Grammont, Franck; Jabaudon, Denis; Studer, Michele; Alfano, Christian

    2016-01-27

    During cortical development, the identity of major classes of long-distance projection neurons is established by the expression of molecular determinants, which become gradually restricted and mutually exclusive. However, the mechanisms by which projection neurons acquire their final properties during postnatal stages are still poorly understood. In this study, we show that the number of neurons co-expressing Ctip2 and Satb2, respectively involved in the early specification of subcerebral and callosal projection neurons, progressively increases after birth in the somatosensory cortex. Ctip2/Satb2 postnatal co-localization defines two distinct neuronal subclasses projecting either to the contralateral cortex or to the brainstem suggesting that Ctip2/Satb2 co-expression may refine their properties rather than determine their identity. Gain- and loss-of-function approaches reveal that the transcriptional adaptor Lmo4 drives this maturation program through modulation of epigenetic mechanisms in a time- and area-specific manner, thereby indicating that a previously unknown genetic program postnatally promotes the acquisition of final subtype-specific features.

  3. Spectrum Trading for Efficient Spectrum Utilization

    Directory of Open Access Journals (Sweden)

    Cong Xiong

    2014-04-01

    Full Text Available The conventional command and control based spectrum management has led to substantial underutilization of some spectrum bands while severely crowding others due to the uneven and dynamic needs that vary over time and at different locations. Spectrum trading has emerged as a promising management approach to substantially improve spectrum utilization and user experience in wireless communications by taking advantage of market-based mechanisms. This article presents an overview of spectrum trading, including the fundamental characteristics of spectrum trading markets, the state-of-the-art techniques for modeling and resolving various spectrum trading issues, and trading based dynamic spectrum sharing and access. Moreover, some open issues in spectrum trading are identified for future research in this area.

  4. High specific surface area Mo2C nanoparticles as an efficient electrocatalyst for hydrogen evolution

    Science.gov (United States)

    Tang, Chaoyun; Sun, Aokui; Xu, Yushuai; Wu, Zhuangzhi; Wang, Dezhi

    2015-11-01

    Mo2C nanoparticles with high specific surface area (120 m2 g-1) are successfully synthesized using a typical and low-cost monosaccharide of glucose via a facile calcination and subsequent reduction process. The HER functions of the obtained Mo2C nanoparticles are investigated and the effect of reduction time in hydrogen is also discussed. It is found that η-MoC can be obtained at 800 °C with a reduction time of 10 min, but the formation of β-Mo2C phase requires more than 20 min. Moreover, the β-Mo2C obtained with a reduction time of 20 min exhibits the best HER activity with a small Tafel slope of 55 mV dec-1 and a large current density of 60 mA cm-2 at -200 mV, which is among the best records over Mo2C-based HER catalysts.

  5. Soil Specific Surface Area and Non-Singularity of Soil-Water Retention at Low Saturations

    DEFF Research Database (Denmark)

    Arthur, Emmanuel; Tuller, Markus; Møldrup, Per

    2013-01-01

    The dry end of the soil water characteristic (SWC) is important for modeling vapor flow dynamics and predicting soil properties such as specific surface area (SSA) and clay content (CL). Verification of new instrumentation for rapid measurement of the dry end of the SWC is relevant to avoid long...... equilibration times and potential for hydraulic decoupling. The objectives of this study were to measure both adsorption and desorption branches of the dry end of the SWC for 21 variably-textured Arizona soils using new, fully automated instrumentation (AquaSorp); apply the data to parameterize the Tuller...... comparable to SSAEGME for all soils. The matric potential at “zero” water content was confirmed as the widely accepted value of around –800 MPa. A non-singularity coefficient based on water adsorption at monolayer coverage was positively correlated with CL. Obtained results show the potential of the Aqua...

  6. General surgery training in Spain: core curriculum and specific areas of training.

    Science.gov (United States)

    Miguelena Bobadilla, José Ma; Morales-García, Dieter; Iturburu Belmonte, Ignacio; Alcázar Montero, José Antonio; Serra Aracil, Xabier; Docobo Durantez, Fernando; López de Cenarruzabeitia, Ignacio; Sanz Sánchez, Mercedes; Hernández Hernández, Juan Ramón

    2015-03-01

    The royal decree RD 639/2014 has been published, regulating among others, the core curriculum, and specific areas of training (SAT). It is of great interest for the specialty of General and Digestive Surgery (GS and DS). The aim is to expose and clarify the main provisions and reflect on their implications for the practical application of the core curriculum and SAT in the specialty of General and Digestive Surgery, to promote initiatives and regulations. This RD will be a milestone in our specialty that will test the strength of the specialty, if it does not finally culminate in its degradation against the emergence of new surgical specialties. A new stage begins in which the Spanish Association of Surgeons should be involved to define the conceptual basis of GS and DS in the XXI century, and the creation of new SAT to continue to maintain the "essence of our specialty".

  7. Area Specific Stripping of lower energy windows for AGS and CGS NaI systems

    DEFF Research Database (Denmark)

    Korsbech, Uffe C C; Aage, Helle Karina; Byström, Sören;

    By the Area Specific Stripping (ASS) method for NaI gamma detectors it is possible in a simple way obtain the parameters (stripping factors) that are needed for being able to discern between natural radioactivity signals and signals from manmade radioactivity and radiation anomalies in general....... The method has earlier been tested only for a few sets of Danish AGS and CGS data. 1. One of the goals of the project has been to investigate to which extent is it possible to use the ASS method for a number of different sets of gamma spectra recorded by different teams with different types of equipment...... in different environments. 2. Another goal of the project has been to investigate why (earlier) one sometimes got oddly-looking ASS parameters that worked correctly when seen from a mathematical point of view but seemingly had no physical meaning. 3. It was also a goal that the successful parts of the ASS...

  8. Low but Increasing Prevalence of Autism Spectrum Disorders in a French Area from Register-Based Data

    Science.gov (United States)

    van Bakel, Marit Maria; Delobel-Ayoub, Malika; Cans, Christine; Assouline, Brigitte; Jouk, Pierre-Simon; Raynaud, Jean-Philippe; Arnaud, Catherine

    2015-01-01

    Register-based prevalence rates of childhood autism (CA), Asperger's syndrome (AS) and other autism spectrum disorders (ASD) were calculated among children aged 7 years old of the 1997-2003 birth cohorts, living in four counties in France. The proportion of children presenting comorbidities was reported. 1123 children with ASD were recorded (M/F…

  9. Birth Prevalence of Autism Spectrum Disorders in the San Francisco Bay Area by Demographic and Ascertainment Source Characteristics

    Science.gov (United States)

    Windham, Gayle C.; Anderson, Meredith C.; Croen, Lisa A.; Smith, Karen S.; Collins, John; Grether, Judith K.

    2011-01-01

    Using standardized methods for multi-source surveillance, we calculated the prevalence of autism spectrum disorders (ASD) among children born in a racially diverse region in 1994 or 1996 as 4.7/1000 live births. Children with ASD before age 9 were identified through chart abstraction at health-related sources; three-quarters were being served by…

  10. Evolution of the Specific Surface Area of Snow in a High Temperature Gradient Metamorphism

    Science.gov (United States)

    Wang, X.; Baker, I.

    2014-12-01

    The structural evolution of low-density snow under a high temperature gradient over a short period usually takes place in the surface layers during diurnal recrystallization or on a clear, cold night. To relate snow microstructures with their thermal properties, we combined X-ray computed microtomography (micro-CT) observations with numerical simulations. Different types of snow were tested over a large range of TGs (100 K m-1- 500 K m-1). The Specific Surface Area (SSA) was used to characterize the temperature gradient metamorphism (TGM). The magnitude of the temperature gradient and the initial snow type both influence the evolution of SSA. The SSA evolution under TGM was dominated by grain growth and the formation of complex surfaces. Fresh snow experienced a logarithmic decrease of SSA with time, a feature been observed previously by others [Calonne et al., 2014; Schneebeli and Sokratov, 2004; Taillandier et al., 2007]. However, for initial rounded and connected snow structures, the SSA will increase during TGM. Understanding the SSA increase is important in order to predict the enhanced uptake of chemical species by snow or increase in snow albedo. Calonne, N., F. Flin, C. Geindreau, B. Lesaffre, and S. Rolland du Roscoat (2014), Study of a temperature gradient metamorphism of snow from 3-D images: time evolution of microstructures, physical properties and their associated anisotropy, The Cryosphere Discussions, 8, 1407-1451, doi:10.5194/tcd-8-1407-2014. Schneebeli, M., and S. A. Sokratov (2004), Tomography of temperature gradient metamorphism of snow and associated changes in heat conductivity, Hydrological Processes, 18(18), 3655-3665, doi:10.1002/hyp.5800. Taillandier, A. S., F. Domine, W. R. Simpson, M. Sturm, and T. A. Douglas (2007), Rate of decrease of the specific surface area of dry snow: Isothermal and temperature gradient conditions, Journal of Geophysical Research: Earth Surface (2003-2012), 112(F3), doi: 10.1029/2006JF000514.

  11. Specific amino acids inhibit food intake via the area postrema or vagal afferents.

    Science.gov (United States)

    Jordi, Josua; Herzog, Brigitte; Camargo, Simone M R; Boyle, Christina N; Lutz, Thomas A; Verrey, François

    2013-11-15

    To maintain nutrient homeostasis the central nervous system integrates signals that promote or inhibit eating. The supply of vital amino acids is tuned by adjusting food intake according to its dietary protein content. We hypothesized that this effect is based on the sensing of individual amino acids as a signal to control food intake. Here, we show that food intake was most potently reduced by oral L-arginine (Arg), L-lysine (Lys) and L-glutamic acid (Glu) compared to all other 17 proteogenic amino acids in rats. These three amino acids induced neuronal activity in the area postrema and the nucleus of the solitary tract. Surgical lesion of the area postrema abolished the anorectic response to Arg and Glu, whereas vagal afferent lesion prevented the response to Lys. These three amino acids also provoked gastric distension by differentially altering gastric secretion and/or emptying. Importantly, these peripheral mechanical vagal stimuli were dissociated from the amino acids' effect on food intake. Thus, Arg, Lys and Glu had a selective impact on food processing and intake suggesting them as direct sensory input to assess dietary protein content and quality in vivo. Overall, this study reveals novel amino acid-specific mechanisms for the control of food intake and of gastrointestinal function.

  12. Determination of the specific surface area of snow using ozonation of 1,1-diphenylethylene.

    Science.gov (United States)

    Ray, Debajyoti; Kurková, Romana; Hovorková, Ivana; Klán, Petr

    2011-12-01

    We measured the kinetics of ozonation reaction of 1,1-diphenylethylene (DPE) in artificial snow, produced by shock freezing of DPE aqueous solutions sprayed into liquid nitrogen. It was demonstrated that most of the reactant molecules are in direct (productive) contact with gaseous ozone, thus the technique produces snow with organic molecules largely ejected to the surface of snow grains. The kinetic data were used to evaluate the snow specific surface area (∼70 cm(2) g(-1)). This number is a measure of the availability of the molecules on the surface for chemical reaction with gaseous species. The experimental results were consistent with the Langmuir-Hinshelwood type reaction mechanism. DPE represents environmentally relevant compounds such as alkenes which can react with atmospheric ozone, and are relatively abundant in natural snow. For typical atmospheric ozone concentrations in polar areas (20 ppbv), we estimated that half-life of DPE on the surface of snow grains is ∼5 days at submonolayer coverages and -15 °C.

  13. Recombinant N-Domain of Pregnancy-Specific Glycoprotein from E. coli Cells: Analysis of the Spectrum of Polyclonal Antibodies.

    Science.gov (United States)

    Prokopenko, P G; Shkoporov, A N; Petrenko, O Yu; Efimov, B A; Negrebetskii, V V; Terent'ev, A A

    2015-11-01

    We studied antibody spectrum in antisera to IgG-like recombinant N-domain of pregnancyspecific glycoprotein-1 (rPSG-N) from E. coli cells. In three experimental series, the fraction of IgG antibodies from anti-rPSG-N sera was immobilized on 3 immunoadsorbents: by polymerization with glutaraldehyde, on glutaraldehyde activated biogel P-300, and on commercial CNBr-activated 4B sepharose. Retroplacental serum was incubated with immobilized antibodies to rPSG1-N, protein was eluted and tested in the precipitation test in standard test systems with PSG1, IgG, and human serum albumin. Three proteins were eluted from all 3 immunoadsorbents: PSG1, IgG, and human serum albumin, which demonstrated the spectrum of antibodies to 3 proteins present also in natural serum PSG1 complex. The proportions of PSG1 and IgG obtained in these experiments were similar to those in natural serum PSG1 complex, while the level of human serum albumin was significantly higher in natural PSG1 complex. Thus, we failed to obtain PSG1 monoprotein free from IgG and human serum albumin. Antigenic mosaicism of the polypeptide chain of IgG-like rPSG1-N relative to the antigenic polyvalence of the complex of three proteins present in bioactive preparation of natural serum PSG1 was discussed.

  14. Real-time specific surface area measurements via laser-induced breakdown spectroscopy

    Science.gov (United States)

    Washburn, Kathryn E.; Birdwell, Justin E.; Howard, James E.

    2017-01-01

    From healthcare to cosmetics to environmental science, the specific surface area (SSA) of micro- and mesoporous materials or products can greatly affect their chemical and physical properties. SSA results are also widely used to examine source rocks in conventional and unconventional petroleum resource plays. Despite its importance, current methods to measure SSA are often cumbersome, time-consuming, or require cryogenic consumables (e.g., liquid nitrogen). These methods are not amenable to high-throughput environments, have stringent sample preparation requirements, and are not practical for use in the field. We present a new application of laser-induced breakdown spectroscopy for rapid measurement of SSA. This study evaluates geological samples, specifically organic-rich oil shales, but the approach is expected to be applicable to many other types of materials. The method uses optical emission spectroscopy to examine laser-generated plasma and quantify the amount of argon adsorbed to a sample during an inert gas purge. The technique can accommodate a wide range of sample sizes and geometries and has the potential for field use. These advantages for SSA measurement combined with the simultaneous acquisition of composition information make this a promising new approach for characterizing geologic samples and other materials.

  15. Reliable nanomaterial classification of powders using the volume-specific surface area method

    Science.gov (United States)

    Wohlleben, Wendel; Mielke, Johannes; Bianchin, Alvise; Ghanem, Antoine; Freiberger, Harald; Rauscher, Hubert; Gemeinert, Marion; Hodoroaba, Vasile-Dan

    2017-02-01

    The volume-specific surface area (VSSA) of a particulate material is one of two apparently very different metrics recommended by the European Commission for a definition of "nanomaterial" for regulatory purposes: specifically, the VSSA metric may classify nanomaterials and non-nanomaterials differently than the median size in number metrics, depending on the chemical composition, size, polydispersity, shape, porosity, and aggregation of the particles in the powder. Here we evaluate the extent of agreement between classification by electron microscopy (EM) and classification by VSSA on a large set of diverse particulate substances that represent all the anticipated challenges except mixtures of different substances. EM and VSSA are determined in multiple labs to assess also the level of reproducibility. Based on the results obtained on highly characterized benchmark materials from the NanoDefine EU FP7 project, we derive a tiered screening strategy for the purpose of implementing the definition of nanomaterials. We finally apply the screening strategy to further industrial materials, which were classified correctly and left only borderline cases for EM. On platelet-shaped nanomaterials, VSSA is essential to prevent false-negative classification by EM. On porous materials, approaches involving extended adsorption isotherms prevent false positive classification by VSSA. We find no false negatives by VSSA, neither in Tier 1 nor in Tier 2, despite real-world industrial polydispersity and diverse composition, shape, and coatings. The VSSA screening strategy is recommended for inclusion in a technical guidance for the implementation of the definition.

  16. Control of a specific motor program by a small brain area in zebrafish

    Directory of Open Access Journals (Sweden)

    Otto eFajardo

    2013-04-01

    Full Text Available Complex motor behaviors are thought to be coordinated by networks of brain nuclei that may control different elementary motor programs. Transparent zebrafish larvae offer the opportunity to analyze the functional organization of motor control networks by optical manipulations of neuronal activity during behavior. We examined motor behavior in transgenic larvae expressing channelrhodopsin-2 throughout many neurons in the brain. Wide-field optical stimulation triggered backward and rotating movements caused by the repeated execution of J-turns, a specific motor program that normally occurs during prey capture. Although optically evoked activity was widespread, behavioral responses were highly coordinated and lateralized. 3-D mapping of behavioral responses to local optical stimuli revealed that J-turns can be triggered specifically in the anterior-ventral optic tectum and/or the adjacent pretectum. These results suggest that the execution of J-turns is controlled by a small group of neurons in the midbrain that may act as a command center. The identification of a brain area controlling a defined motor program involved in prey capture is a step towards a comprehensive analysis of neuronal circuits mediating sensorimotor behaviors of zebrafish.

  17. Unsuppressible Repetition Suppression and exemplar-specific Expectation Suppression in the Fusiform Face Area.

    Science.gov (United States)

    Pajani, Auréliane; Kouider, Sid; Roux, Paul; de Gardelle, Vincent

    2017-12-01

    Recent work casts Repetition Suppression (RS), i.e. the reduced neural response to repeated stimuli, as the consequence of reduced surprise for repeated inputs. This research, along with other studies documenting Expectation Suppression, i.e. reduced responses to expected stimuli, emphasizes the role of expectations and predictive codes in perception. Here, we use fMRI to further characterize the nature of predictive signals in the human brain. Prior to scanning, participants were implicitly exposed to associations within face pairs. Critically, we found that this resulted in exemplar-specific Expectation Suppression in the fusiform face-sensitive area (FFA): individual faces that could be predicted from the associations elicited reduced FFA responses, as compared to unpredictable faces. Thus, predictive signals in the FFA are specific to face exemplars, and not only generic to the category of face stimuli. In addition, we show that under such circumstances, the occurrence of surprising repetitions did not trigger enhanced brain responses, as had been recently hypothesized, but still suppressed responses, suggesting that repetition suppression might be partly 'unsuppressible'. Repetition effects cannot be fully modulated by expectations, which supports the recent view that expectation and repetition effects rest on partially independent mechanisms. Altogether, our study sheds light on the nature of expectation signals along the perceptual system.

  18. Mapping of 137Cs in Ida-Virumaa, June 2005. CGS Area Specific Spectrum Stripping and ESC from soil sampling

    DEFF Research Database (Denmark)

    Aage, Helle Karina; Korsbech, Uffe C C

    This report describes some results from a Baltic-Danish exercise with carborne gamma-ray spectrometry (CGS) measurements performed in Estonia in the summer of 2005. The goal was to measure the low level of contamination with 137Cs that still exists as part of the fall-out from the Chernobyl...... accident in April 1986. Another goal was to check the sensitivity calibration of the systems from soil sampling by the Estonian Radiation Protection Centre (ERPC)....

  19. A Prospective Study on the Clinical and Microbiological Spectrum of Endophthalmitis in a Specific Region in Denmark

    DEFF Research Database (Denmark)

    Solborg Bjerrum, Søren; Hamoudi, Hassan; Friis-Møller, Alice;

    2016-01-01

    clinically examined before, during and after surgical intervention for endophthalmitis. RESULTS: Fifty eyes with endophthalmitis were included. Endophthalmitis after cataract surgery (post-cataract), anti-VEGF (vascular endothelial growth factor) intravitreal injections (post-injection) and cases...... of endogenous endophthalmitis were responsible for 40, 28 and 18% of all cases, respectively. There was no difference in the microbiological spectrum in post-cataract patients and post-injection patients, but patients with post-cataract endophthalmitis presented statistically significantly more frequently...... with hypopyon and fibrin in the anterior chamber. Between 20 and 25% of post-cataract and post-injection endophthalmitis patients developed a surgical complication after primary surgical intervention for endophthalmitis, and this was statistically significantly associated with a poor visual outcome...

  20. Glacier length, area and volume changes in the Himalaya: an overview and specific examples

    Science.gov (United States)

    Bolch, T.; Bhambri, R.; Kamp, U.; Pieczonka, T.

    2011-12-01

    advancing glaciers. This is consistent with existing studies of the Karakoram glaciers. However, area and length changes show indirect signals only while the mass balance is most directly linked to climate. Debris cover on glaciers which is common throughout the Himalaya further influences glacier melt. Existing studies show that area and length changes are reduced in comparison to debris-free glaciers. Currently no long-term in-situ glacier mass balance measurements exist. Remote sensed derived geodetic mass balance estimations are a suitable tool to improve the knowledge on the reaction of glaciers to climate change. Detailed investigations on the debris-covered glaciers in Khumbu Himalaya based on stereo Corona, ASTER and Cartosat-1 data revealed a specific mass balance of -0.32 ± 0.08 m w.e. a-1 between 1972 and 2007 which is within the global mean. The surface lowering is significant for all glaciers despite thick debris-cover. Consistently, preliminary results of the large debris-covered Zemu Glacier in Sikkim/Eastern Indian Himalaya indicate significant mass loss but only a slight reduction in length. Further analyses are under way and also climatic considerations will be addressed.

  1. Branch age and light conditions determine leaf-area-specific conductivity in current shoots of Scots pine.

    Science.gov (United States)

    Grönlund, Leila; Hölttä, Teemu; Mäkelä, Annikki

    2016-08-01

    Shoot size and other shoot properties more or less follow the availability of light, but there is also evidence that the topological position in a tree crown has an influence on shoot development. Whether the hydraulic properties of new shoots are more regulated by the light or the position affects the shoot acclimation to changing light conditions and thereby to changing evaporative demand. We investigated the leaf-area-specific conductivity (and its components sapwood-specific conductivity and Huber value) of the current-year shoots of Scots pine (Pinus sylvestris L.) in relation to light environment and topological position in three different tree classes. The light environment was quantified in terms of simulated transpiration and the topological position was quantified by parent branch age. Sample shoot measurements included length, basal and tip diameter, hydraulic conductivity of the shoot, tracheid area and density, and specific leaf area. In our results, the leaf-area-specific conductivity of new shoots declined with parent branch age and increased with simulated transpiration rate of the shoot. The relation to transpiration demand seemed more decisive, since it gave higher R(2) values than branch age and explained the differences between the tree classes. The trend of leaf-area-specific conductivity with simulated transpiration was closely related to Huber value, whereas the trend of leaf-area-specific conductivity with parent branch age was related to a similar trend in sapwood-specific conductivity.

  2. Nickel catalysts supported on MgO with different specific surface area for carbon dioxide reforming of methane

    Institute of Scientific and Technical Information of China (English)

    Luming; Zhang; Lin; Li; Yuhua; Zhang; Yanxi; Zhao; Jinlin; Li

    2014-01-01

    In this paper, three kinds of MgO with different specific surface area were prepared, and their effects on the catalytic performance of nickel catalysts for the carbon dioxide reforming of methane were investigated. The results showed that MgO support with the higher specific surface area led to the higher dispersion of the active metal, which resulted in the higher initial activity. On the other hand, the specific surface area of MgO materials might not be the dominant factor for the basicity of support to chemisorb and activate CO2, which was another important factor for the performance of catalysts. Herein, Ni/MgO(CA) catalyst with proper specific surface area and strong ability to activate CO2exhibited stable catalytic property and the carbon species deposited on the Ni/MgO(CA) catalyst after 10 h of reaction at 650 ?C were mainly activated carbon species.

  3. Measurement of the Cosmic Ray e+ plus e- Spectrum from 20 GeV to 1 TeV with the Fermi Large Area Telescope

    Energy Technology Data Exchange (ETDEWEB)

    Abdo, Aous A.; /Naval Research Lab, Wash., D.C.; Ackermann, M.; /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept.; Ajello, M.; /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept.; Atwood, W.B.; /UC, Santa Cruz; Axelsson, M.; /Stockholm U., OKC /Stockholm U.; Baldini, L.; /INFN, Pisa; Ballet, J.; /DAPNIA, Saclay; Barbiellini, Guido; /INFN, Trieste /Trieste U.; Bastieri, Denis; /INFN, Padua /Padua U.; Battelino, M.; /Stockholm U., OKC /Royal Inst. Tech., Stockholm; Baughman, B.M.; /Ohio State U.; Bechtol, K.; /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept.; Bellazzini, R.; /INFN, Pisa; Berenji, B.; /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept.; Blandford, R.D.; /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept.; Bloom, Elliott D.; /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept.; Bogaert, G.; /Ecole Polytechnique; Bonamente, E.; /INFN, Perugia /Perugia U.; Borgland, A.W.; /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept.; Bregeon, J.; /INFN, Pisa; Brez, A.; /INFN, Pisa /Bari U. /INFN, Bari /Ecole Polytechnique /Washington U., Seattle /Bari U. /INFN, Bari /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /IASF, Milan /IASF, Milan /Stockholm U., OKC /Royal Inst. Tech., Stockholm /DAPNIA, Saclay /INFN, Perugia /Perugia U. /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /George Mason U. /Naval Research Lab, Wash., D.C. /NASA, Goddard /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /INFN, Perugia /Perugia U. /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /Montpellier U. /Sonoma State U. /Stockholm U., OKC /Royal Inst. Tech., Stockholm /Stockholm U. /ASDC, Frascati /Naval Research Lab, Wash., D.C. /INFN, Trieste /Bari U. /INFN, Bari /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /INFN, Pisa /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /CENBG, Gradignan /CENBG, Gradignan /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /Montpellier U. /Bari U. /INFN, Bari; /more authors..

    2012-05-14

    Designed as a high-sensitivity gamma-ray observatory, the Fermi Large Area Telescope is also an electron detector with a large acceptance exceeding 2 m{sup 2}sr at 300 GeV. Building on the gamma-ray analysis, we have developed an efficient electron detection strategy which provides sufficient background rejection for measurement of the steeply-falling electron spectrum up to 1 TeV. Our high precision data show that the electron spectrum falls with energy as E{sup -3.0} and does not exhibit prominent spectral features. Interpretations in terms of a conventional diffusive model as well as a potential local extra component are briefly discussed.

  4. Retrieval of snow Specific Surface Area (SSA) from MODIS data in mountainous regions

    Science.gov (United States)

    Mary, A.; Dumont, M.; Dedieu, J.-P.; Durand, Y.; Sirguey, P.; Milhem, H.; Mestre, O.; Negi, H. S.; Kokhanovsky, A. A.

    2012-05-01

    This study describes a method to retrieve snow specific surface area (SSA) from satellite radiance reasurements in mountainous terrain. It aims at comparing different retrieval methods and at addressing topographic corrections of reflectance, namely slope and aspect of terrain and multiple reflections on neighbouring slopes. We use an iterative algorithm to compute reflectance from radiance of the MODerate resolution Imaging Spectrometer (MODIS) with a comprehensive correction of local illumination with regards to topography. The retrieved SSA is compared to the results of the snowpack model Crocus, fed by driving data from the SAFRAN meteorological analysis, over a large domain in the French Alps. We compared SSA retrievals with and without topographic or anisotropy correction, and with a spherical or non-spherical snow reflectance model. The topographic correction enables SSA to be retrieved in better agreement with those from SAFRAN-Crocus. The root mean square deviation is 10.0 m2 kg-1 and the bias is -0.6 m2 kg-1, over 3829 pixels representing seven different dates and snow conditions. The standard deviation of MODIS retrieved data, larger than the one of SAFRAN-Crocus estimates, is responsible for half this RMSD. It is due to the topographic classes used by SAFRAN-Crocus. In addition, MODIS retrieved data show SSA gradients with elevation and solar exposition, physically consistent and in good agreement with SAFRAN-Crocus.

  5. Retrieval of snow Specific Surface Area (SSA from MODIS data in mountainous regions

    Directory of Open Access Journals (Sweden)

    A. Mary

    2012-05-01

    Full Text Available This study describes a method to retrieve snow specific surface area (SSA from satellite radiance reasurements in mountainous terrain. It aims at comparing different retrieval methods and at addressing topographic corrections of reflectance, namely slope and aspect of terrain and multiple reflections on neighbouring slopes. We use an iterative algorithm to compute reflectance from radiance of the MODerate resolution Imaging Spectrometer (MODIS with a comprehensive correction of local illumination with regards to topography. The retrieved SSA is compared to the results of the snowpack model Crocus, fed by driving data from the SAFRAN meteorological analysis, over a large domain in the French Alps. We compared SSA retrievals with and without topographic or anisotropy correction, and with a spherical or non-spherical snow reflectance model. The topographic correction enables SSA to be retrieved in better agreement with those from SAFRAN-Crocus. The root mean square deviation is 10.0 m2 kg−1 and the bias is −0.6 m2 kg−1, over 3829 pixels representing seven different dates and snow conditions. The standard deviation of MODIS retrieved data, larger than the one of SAFRAN-Crocus estimates, is responsible for half this RMSD. It is due to the topographic classes used by SAFRAN-Crocus. In addition, MODIS retrieved data show SSA gradients with elevation and solar exposition, physically consistent and in good agreement with SAFRAN-Crocus.

  6. Ecological strategies in california chaparral: Interacting effects of soils, climate, and fire on specific leaf area

    Science.gov (United States)

    Anacker, Brian; Rajakaruna, Nishanta; Ackerly, David; Harrison, Susan; Keeley, Jon E.; Vasey, Michael

    2011-01-01

    Background: High values of specific leaf area (SLA) are generally associated with high maximal growth rates in resource-rich conditions, such as mesic climates and fertile soils. However, fire may complicate this relationship since its frequency varies with both climate and soil fertility, and fire frequency selects for regeneration strategies (resprouting versus seeding) that are not independent of resource-acquisition strategies. Shared ancestry is also expected to affect the distribution of resource-use and regeneration traits.Aims: We examined climate, soil, and fire as drivers of community-level variation in a key functional trait, SLA, in chaparral in California.Methods: We quantified the phylogenetic, functional, and environmental non-independence of key traits for 87 species in 115 plots.Results: Among species, SLA was higher in resprouters than seeders, although not after phylogeny correction. Among communities, mean SLA was lower in harsh interior climates, but in these climates it was higher on more fertile soils and on more recently burned sites; in mesic coastal climates, mean SLA was uniformly high despite variation in soil fertility and fire history.Conclusions: We conclude that because important correlations exist among both species traits and environmental filters, interpreting the functional and phylogenetic structure of communities may require an understanding of complex interactive effects.

  7. Rate of evolution of the specific surface area of surface snow layers.

    Science.gov (United States)

    Cabanes, Axel; Legagneux, Loïc; Dominé, Florent

    2003-02-15

    The snowpack can impact atmospheric chemistry by exchanging adsorbed or dissolved gases with the atmosphere. Modeling this impact requires the knowledge of the specific surface area (SSA) of snow and its variations with time. We have therefore measured the evolution of the SSA of eight recent surface snow layers in the Arctic and the French Alps, using CH4 adsorption at liquid nitrogen temperature (77 K). The SSA of fresh snow layers was found to decrease with time, from initial values in the range 613-1540 cm2/g to values as low as 257 cm2/g after 6 days. This is explained by snow metamorphism, which causes modifications in crystal shapes, here essentially crystal rounding and the disappearance of microstructures. A parametrization of the rate of SSA decrease is proposed. We fit the SSA decrease to an exponential law and find that the time constant alpha(exp) (day(-1)) depends on temperature according to alpha(exp) = 76.6 exp (-1708/7), with Tin kelvin. Our parametrization predicts that the SSA of a snow layer evolving at -40 degrees C will decrease by a factor of 2 after 14 days, while a similar decrease at -1 degrees C will only require 5 days. Wind was found to increase the rate of SSA decrease, but insufficient data did not allow a parametrization of this effect.

  8. Measuring the specific surface area of wet snow using 1310 nm reflectance

    Directory of Open Access Journals (Sweden)

    J.-C. Gallet

    2013-10-01

    Full Text Available The specific surface area (SSA of snow can be used as an objective measurement of grain size and is therefore a central variable to describe snow physical properties such as albedo. Snow SSA can now be easily measured in the field using optical methods based on infrared reflectance. However, existing optical methods have only been validated for dry snow. Here we test the possibility to use the DUFISSS instrument, based on the measurement of the 1310 nm reflectance of snow with an integrating sphere, to measure the SSA of wet snow. We perform cold room experiments where we measure the SSA of a wet snow sample, freeze it and measure it again, to quantify the difference in reflectance between frozen and wet snow. We study snow samples in the SSA range 12–37 m2 kg−1 and in the mass liquid water content range 5–32%. We conclude that the SSA of wet snow can be obtained from the measurement of its 1310 nm reflectance using three simple steps. In most cases, the SSA thus obtained is less than 10% different from the value that would have been obtained if the sample had been considered dry, so that the three simple steps constitute a minor correction. We also run two optical models to interpret the results, but no model reproduces correctly the water-ice distribution in wet snow, so that their predictions of wet snow reflectance are imperfect.

  9. Further Evidence of Mutational Heterogeneity of the XPC Gene in Tunisian Families: A Spectrum of Private and Ethnic Specific Mutations

    Directory of Open Access Journals (Sweden)

    Mariem Ben Rekaya

    2013-01-01

    Full Text Available Xeroderma Pigmentosum (XP is a rare recessive autosomal cancer prone disease, characterized by UV hypersensitivity and early appearance of cutaneous and ocular malignancies. We investigated four unrelated patients suspected to be XP-C. To confirm linkage to XPC gene, genotyping and direct sequencing of XPC gene were performed. Pathogenic effect of novel mutations was confirmed by reverse Transciptase PCR. Mutation screening revealed the presence of two novel mutations g.18246G>A and g.18810G>T in the XPC gene (NG_011763.1. The first is present in one patient XP50NEF, but the second is present in three unrelated patients (XP16KEB, XP28SFA, and XP45GB. These 3 patients are from three different cities of Southern Tunisia and bear the same haplotype, suggesting a founder effect. Reverse Transciptase PCR revealed the absence of the XPC mRNA. In Tunisia, as observed in an other severe genodermatosis, the mutational spectrum of XP-C group seems to be homogeneous with some clusters of heterogeneity that should be taken into account to improve molecular diagnosis of this disease.

  10. Brief report: the dopamine-3-receptor gene (DRD3) is associated with specific repetitive behavior in autism spectrum disorder (ASD)

    NARCIS (Netherlands)

    Staal, W.G.; Krom, M. de; Jonge, M.V. de

    2012-01-01

    Recently the DRD3 gene has been associated with ASD in two independent samples. Follow up analysis of the risk allele of the SNP rs167771 in 91 subjects revealed a significant association with a specific type of repetitive behavior: the factor "insistence on sameness" (IS) derived from the Autism Di

  11. LITERATURE REVIEW OF PUO2 CALCINATION TIME AND TEMPERATURE DATA FOR SPECIFIC SURFACE AREA

    Energy Technology Data Exchange (ETDEWEB)

    Daniel, G.

    2012-03-06

    The literature has been reviewed in December 2011 for calcination data of plutonium oxide (PuO{sub 2}) from plutonium oxalate Pu(C{sub 2}O{sub 4}){sub 2} precipitation with respect to the PuO{sub 2} specific surface area (SSA). A summary of the literature is presented for what are believed to be the dominant factors influencing SSA, the calcination temperature and time. The PuO{sub 2} from Pu(C{sub 2}O{sub 4}){sub 2} calcination data from this review has been regressed to better understand the influence of calcination temperature and time on SSA. Based on this literature review data set, calcination temperature has a bigger impact on SSA versus time. However, there is still some variance in this data set that may be reflecting differences in the plutonium oxalate preparation or different calcination techniques. It is evident from this review that additional calcination temperature and time data for PuO{sub 2} from Pu(C{sub 2}O{sub 4}){sub 2} needs to be collected and evaluated to better define the relationship. The existing data set has a lot of calcination times that are about 2 hours and therefore may be underestimating the impact of heating time on SSA. SRNL recommends that more calcination temperature and time data for PuO{sub 2} from Pu(C{sub 2}O{sub 4}){sub 2} be collected and this literature review data set be augmented to better refine the relationship between PuO{sub 2} SSA and its calcination parameters.

  12. Spectrum of allergens for Japanese cedar pollinosis and impact of component-resolved diagnosis on allergen-specific immunotherapy.

    Science.gov (United States)

    Fujimura, Takashi; Kawamoto, Seiji

    2015-10-01

    The high prevalence of Japanese cedar pollinosis in Japan is associated with a negative impact on the quality of life of patients, as well as significant loss of productivity among the workforce in early spring, thus representing a serious social problem. Furthermore, the prevalence is increasing, and has risen by more than 10% in this decade. Cry j 1 and Cry j 2 were identified as the major allergens in Japanese cedar pollen (JCP), and in 2004, the existence of other major and minor allergens were revealed by a combination of two-dimensional electrophoresis and immunoblotting analysis. Allergenome analysis identified a chitinase, a lipid transfer protein, a serine protease, and an aspartic protease as novel IgE-reactive allergens in patients with JCP allergy. Thaumatin-like protein (Cry j 3) was shown to be homologous to Jun a 3, a major allergen from mountain cedar pollen. Isoflavone reductase-like protein was also characterized in a study of a JCP cDNA library. The characterization of component allergens is required to clarify the sensitizer or cross-reactive elicitor allergens for component-resolved diagnosis (CRD). Increasing evidence from numerous clinical trials indicates that CRD can be used to design effective allergen-specific immunotherapy. In this review, we summarize the eight characterized JCP allergens and discuss the impact of CRD and characterization of novel allergens on allergen-specific immunotherapy.

  13. On area-specific underground research laboratory for geological disposal of high-level radioactive waste in China

    Directory of Open Access Journals (Sweden)

    Ju Wang

    2014-04-01

    Full Text Available Underground research laboratories (URLs, including “generic URLs” and “site-specific URLs”, are underground facilities in which characterisation, testing, technology development, and/or demonstration activities are carried out in support of the development of geological repositories for high-level radioactive waste (HLW disposal. In addition to the generic URL and site-specific URL, a concept of “area-specific URL”, or the third type of URL, is proposed in this paper. It is referred to as the facility that is built at a site within an area that is considered as a potential area for HLW repository or built at a place near the future repository site, and may be regarded as a precursor to the development of a repository at the site. It acts as a “generic URL”, but also acts as a “site-specific URL” to some extent. Considering the current situation in China, the most suitable option is to build an “area-specific URL” in Beishan area, the first priority region for China's high-level waste repository. With this strategy, the goal to build China's URL by 2020 may be achieved, but the time left is limited.

  14. On area-specific underground research laboratory for geological disposal of high-level radioactive waste in China

    Institute of Scientific and Technical Information of China (English)

    Ju Wang

    2014-01-01

    Underground research laboratories (URLs), including “generic URLs” and “site-specific URLs”, are un-derground facilities in which characterisation, testing, technology development, and/or demonstration activities are carried out in support of the development of geological repositories for high-level radio-active waste (HLW) disposal. In addition to the generic URL and site-specific URL, a concept of “area-specific URL”, or the third type of URL, is proposed in this paper. It is referred to as the facility that is built at a site within an area that is considered as a potential area for HLW repository or built at a place near the future repository site, and may be regarded as a precursor to the development of a repository at the site. It acts as a “generic URL”, but also acts as a “site-specific URL” to some extent. Considering the current situation in China, the most suitable option is to build an“area-specific URL”in Beishan area, the first priority region for China’s high-level waste repository. With this strategy, the goal to build China’s URL by 2020 may be achieved, but the time left is limited.

  15. Vertical profiles of the specific surface area of the snow at Dome C, Antarctica

    Directory of Open Access Journals (Sweden)

    J.-C. Gallet

    2010-09-01

    Full Text Available The specific surface area (SSA of snow determines in Part the albedo of snow surfaces and the capacity of the snow to adsorb chemical species and catalyze reactions. Despite these crucial roles, almost no value of snow SSA are available for the largest permanent snow expanse on Earth, the Antarctic. We have measured the first vertical profiles of snow SSA near Dome C (DC: 75°06´ S, 123°20´ E, 3233 m a.s.l. on the Antarctic plateau, and at seven sites during the logistical traverse between Dome C and the French coastal base Dumont D'Urville (DDU: 66°40´ S, 140°01´ E during the Austral summer 2008–2009. We used the DUFISSS system, which measures the IR reflectance of snow at 1310 nm with an integrating sphere. At DC, the mean SSA of the snow in the top 1 cm is 38 m2 kg−1, decreasing monotonically to 14 m2 kg−1 at a depth of 15 cm. Along the traverse, the snow SSA profile is similar to that at DC in the first 600 km from DC. Closer to DDU, the SSA of the top 5 cm is 23 m2 kg−1, decreasing to 19 m2 kg−1 at 50 cm depth. This is attributed to wind, which causes a rapid decrease of surface snow SSA, but forms hard windpacks whose SSA decrease more slowly with time. Since light-absorbing impurities are not concentrated enough to affect albedo, the vertical profiles of SSA and density were used to calculate the spectral albedo of the snow for several realistic illumination conditions, using the DISORT radiative transfer model. A preliminary comparison with MODIS data is presented for use in energy balance calculations and for comparison with other satellite retrievals. These calculated albedos are compared to the few existing measurements on the Antarctic plateau. The interest of postulating a submillimetric, high-SSA layer at the snow surface to explain measured albedos is discussed.

  16. Abnormal Functional Lateralization and Activity of Language Brain Areas in Typical Specific Language Impairment (Developmental Dysphasia)

    Science.gov (United States)

    de Guibert, Clement; Maumet, Camille; Jannin, Pierre; Ferre, Jean-Christophe; Treguier, Catherine; Barillot, Christian; Le Rumeur, Elisabeth; Allaire, Catherine; Biraben, Arnaud

    2011-01-01

    Atypical functional lateralization and specialization for language have been proposed to account for developmental language disorders, yet results from functional neuroimaging studies are sparse and inconsistent. This functional magnetic resonance imaging study compared children with a specific subtype of specific language impairment affecting…

  17. Evolution of Specific Surface Area Inside Glass Immersed in Beishan Groundwater

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>The surface area of the fissure inside the glass block is an important parameter influencing the long term behavior of high-level radioactive waste glass in the aqueous media during the deep geological

  18. CERT Resilience Management Model - Mail-Specific Process Areas: International Mail Transportation (Version 1.0)

    Science.gov (United States)

    2014-08-01

    requirements to the physical IMPC facilities where mail transportation activities are conducted and other physical, environmental , and geographical...controls to support the resilience of mail and mail services during transportation are managed in the CERT-RMM Environmental Control process area. The...RISK:SG3 and RISK:SG4 in the CERT-RMM Risk Management process area. Typical Work Products 1. Postal item risk statements, with impact valuation 2

  19. Perspective Biological Markers for Autism Spectrum Disorders: Advantages of the Use of Receiver Operating Characteristic Curves in Evaluating Marker Sensitivity and Specificity

    Directory of Open Access Journals (Sweden)

    Provvidenza M. Abruzzo

    2015-01-01

    Full Text Available Autism Spectrum Disorders (ASD are a heterogeneous group of neurodevelopmental disorders. Recognized causes of ASD include genetic factors, metabolic diseases, toxic and environmental factors, and a combination of these. Available tests fail to recognize genetic abnormalities in about 70% of ASD children, where diagnosis is solely based on behavioral signs and symptoms, which are difficult to evaluate in very young children. Although it is advisable that specific psychotherapeutic and pedagogic interventions are initiated as early as possible, early diagnosis is hampered by the lack of nongenetic specific biological markers. In the past ten years, the scientific literature has reported dozens of neurophysiological and biochemical alterations in ASD children; however no real biomarker has emerged. Such literature is here reviewed in the light of Receiver Operating Characteristic (ROC analysis, a very valuable statistical tool, which evaluates the sensitivity and the specificity of biomarkers to be used in diagnostic decision making. We also apply ROC analysis to some of our previously published data and discuss the increased diagnostic value of combining more variables in one ROC curve analysis. We also discuss the use of biomarkers as a tool for advancing our understanding of nonsyndromic ASD.

  20. Soil Pollution with Heavy Metals - Specific Issues for Baia Mare Area

    Directory of Open Access Journals (Sweden)

    COMAN Mirela

    2010-08-01

    Full Text Available The mining activity, practices in Baia Mare for over 100 years, has led to pollution and economic sealing oflarge areas of land; it has adversely affected the environment and now poses a significant risk to human health. Theactual sources of pollution, current or historical, in Baia Mare Depression are SC Romplumb SA, SC Cuprom SA andCNMPN Remin SA. The mining activities left over wide areas ponds, mine waste dumps and the underground watersthat come across the existing mine galleries spring out contaminated and sometimes in an uncontrolled manner. Heavymetals are present in the environmental factors from this area and significantly affect local ecosystems and humanhealth. The paper presents details on soil pollution with heavy metals, problem that has gradually found a solution in theenvironmental rehabilitation projects, activities that requiring investment of time and specialists in this field.

  1. Economics of Scholarly Publishing: Exploring the Causes of Subscription Price Variations of Scholarly Journals in Business Subject-Specific Areas

    Science.gov (United States)

    Liu, Lewis G.

    2011-01-01

    This empirical research investigates subscription price variations of scholarly journals in five business subject-specific areas using the semilogarithmic regression model. It has two main purposes. The first is to address the unsettled debate over whether or not and to what extent commercial publishers reap monopoly profits by overcharging…

  2. The angular power spectrum of the diffuse gamma-ray emission as measured by the Fermi Large Area Telescope and constraints on its Dark Matter interpretation

    CERN Document Server

    Fornasa, Mattia; Zavala, Jesus; Gaskins, Jennifer M; Sanchez-Conde, Miguel A; Gomez-Vargas, German; Komatsu, Eiichiro; Linden, Tim; Prada, Francisco; Zandanel, Fabio; Morselli, Aldo

    2016-01-01

    The isotropic gamma-ray background arises from the contribution of unresolved sources, including members of confirmed source classes and proposed gamma-ray emitters such as the radiation induced by dark matter annihilation and decay. Clues about the properties of the contributing sources are imprinted in the anisotropy characteristics of the gamma-ray background. We use 81 months of Pass 7 Reprocessed data from the Fermi Large Area Telescope to perform a measurement of the anisotropy angular power spectrum of the gamma-ray background. We analyze energies between 0.5 and 500 GeV, extending the range considered in the previous measurement based on 22 months of data. We also compute, for the first time, the cross-correlation angular power spectrum between different energy bins. We find that the derived angular spectra are compatible with being Poissonian, i.e. constant in multipole. Moreover, the energy dependence of the anisotropy suggests that the signal is due to two populations of sources, contributing, resp...

  3. Chlorine-Induced In Situ Regulation to Synthesize Graphene Frameworks with Large Specific Area for Excellent Supercapacitor Performance.

    Science.gov (United States)

    Zhu, Yanyan; Cui, Huijuan; Meng, Xin; Zheng, Jianfeng; Yang, Pengju; Li, Li; Wang, Zhijian; Jia, Suping; Zhu, Zhenping

    2016-03-01

    Three-dimensional (3D) graphene frameworks are usually limited by a complicated preparation process and a low specific surface area. This paper presents a facile suitable approach to effectively synthesize 3D graphene frameworks (GFs) with large specific surface area (up to 1018 m(2) g(-1)) through quick thermal decomposition from sodium chloroacetate, which are considerably larger than those of sodium acetate reported in our recent study. The chlorine element in sodium chloroacetate may possess a strong capability to induce in situ activation and regulate graphene formation during pyrolysis in one step. These GFs can be applied as excellent electrode materials for supercapacitors and can achieve an enhanced supercapacitor performance with a specific capacitance of 266 F g(-1) at a current density of 0.5 A g(-1).

  4. Electrospun anatase-phase TiO2 nanofibers with different morphological structures and specific surface areas.

    Science.gov (United States)

    He, Guangfei; Cai, Yibing; Zhao, Yong; Wang, Xiaoxu; Lai, Chuilin; Xi, Min; Zhu, Zhengtao; Fong, Hao

    2013-05-15

    Electrospun anatase-phase TiO2 nanofibers with desired morphological structure and relatively high specific surface area are expected to outperform other nanostructures (e.g., powder and film) of TiO2 for various applications (particularly dye-sensitized solar cell and photo-catalysis). In this study, systematic investigations were carried out to prepare and characterize electrospun anatase-phase TiO2 nanofibers with different morphological structures (e.g., solid, hollow/tubular, and porous) and specific surface areas. The TiO2 nanofibers were generally prepared via electrospinning of precursor nanofibers followed by pyrolysis at 500°C. For making hollow/tubular TiO2 nanofibers, the technique of co-axial electrospinning was utilized; while for making porous TiO2 nanofibers, the etching treatment in NaOH aqueous solution was adopted. The results indicated that the hollow/tubular TiO2 nanofibers (with diameters of ~300-500 nm and wall-thickness in the range from tens of nanometers to ~200 nm) had the BET specific surface area of ~27.3 m(2)/g, which was approximately twice as that of the solid TiO2 nanofibers (~15.2 m(2)/g) with diameters of ~200-300 nm and lengths of at least tens of microns. Porous TiO2 nanofibers made from the precursor of Al2O3/TiO2 composite nanofibers had the BET specific surface area of ~106.5 m(2)/g, whereas porous TiO2 nanofibers made from the precursor of ZnO/TiO2 composite nanofibers had the highest BET specific surface area of ~148.6 m(2)/g.

  5. Current models broadly neglect specific needs of biodiversity conservation in protected areas under climate change

    Directory of Open Access Journals (Sweden)

    Moloney Kirk A

    2011-05-01

    Full Text Available Abstract Background Protected areas are the most common and important instrument for the conservation of biological diversity and are called for under the United Nations' Convention on Biological Diversity. Growing human population densities, intensified land-use, invasive species and increasing habitat fragmentation threaten ecosystems worldwide and protected areas are often the only refuge for endangered species. Climate change is posing an additional threat that may also impact ecosystems currently under protection. Therefore, it is of crucial importance to include the potential impact of climate change when designing future nature conservation strategies and implementing protected area management. This approach would go beyond reactive crisis management and, by necessity, would include anticipatory risk assessments. One avenue for doing so is being provided by simulation models that take advantage of the increase in computing capacity and performance that has occurred over the last two decades. Here we review the literature to determine the state-of-the-art in modeling terrestrial protected areas under climate change, with the aim of evaluating and detecting trends and gaps in the current approaches being employed, as well as to provide a useful overview and guidelines for future research. Results Most studies apply statistical, bioclimatic envelope models and focus primarily on plant species as compared to other taxa. Very few studies utilize a mechanistic, process-based approach and none examine biotic interactions like predation and competition. Important factors like land-use, habitat fragmentation, invasion and dispersal are rarely incorporated, restricting the informative value of the resulting predictions considerably. Conclusion The general impression that emerges is that biodiversity conservation in protected areas could benefit from the application of modern modeling approaches to a greater extent than is currently reflected in the

  6. Comparison of Extended-Spectrum β-Lactamase-Producing Escherichia coli Isolates from Drinking Well Water and Pit Latrine Wastewater in a Rural Area of China

    Science.gov (United States)

    Gao, Yanxia

    2016-01-01

    The present study was conducted to gain insights into the occurrence and characteristics of extended-spectrum beta-lactamase- (ESBL-) producing Escherichia coli (E. coli) from drinking well water in the rural area of Laiwu, China, and to explore the role of the nearby pit latrine as a contamination source. ESBL-producing E. coli from wells were compared with isolates from pit latrines in the vicinity. The results showed that ESBL-producing E. coli isolates, with the same antibiotic resistance profiles, ESBL genes, phylogenetic group, plasmid replicon types, and enterobacterial repetitive intergenic consensus-polymerase chain reaction (ERIC-PCR) fingerprints, were isolated from well water and the nearby pit latrine in the same courtyard. Therefore, ESBL-producing E. coli in the pit latrine may be a likely contributor to the presence of ESBL-producing E. coli in rural well water. PMID:27965975

  7. Postsynaptic Target Specific Synaptic Dysfunctions in the CA3 Area of BACE1 Knockout Mice

    OpenAIRE

    2014-01-01

    Beta-amyloid precursor protein cleaving enzyme 1 (BACE1), a major neuronal β-secretase critical for the formation of β-amyloid (Aβ) peptide, is considered one of the key therapeutic targets that can prevent the progression of Alzheimer's disease (AD). Although a complete ablation of BACE1 gene prevents Aβ formation, we previously reported that BACE1 knockouts (KOs) display presynaptic deficits, especially at the mossy fiber (MF) to CA3 synapses. Whether the defect is specific to certain input...

  8. CERT Resilience Management Model - Mail-Specific Process Areas: Mail Induction (Version 1.0)

    Science.gov (United States)

    2014-08-01

    impressed upon employees by supervisors and sustained by the influence of the culture. Specific sanctity controls are applied to mail products, such as use...use of a unique, trackable barcode applied to letters, postcards and flat mailpieces (First-Class, Periodicals, Standard Mail), trays , sacks, and...IMb for letters and flats • IMpb for packages • Intelligent Mail tray barcode (IMtb) for trays and sacks • Intelligent Mail Container barcode

  9. Postsynaptic target specific synaptic dysfunctions in the CA3 area of BACE1 knockout mice.

    Directory of Open Access Journals (Sweden)

    Hui Wang

    Full Text Available Beta-amyloid precursor protein cleaving enzyme 1 (BACE1, a major neuronal β-secretase critical for the formation of β-amyloid (Aβ peptide, is considered one of the key therapeutic targets that can prevent the progression of Alzheimer's disease (AD. Although a complete ablation of BACE1 gene prevents Aβ formation, we previously reported that BACE1 knockouts (KOs display presynaptic deficits, especially at the mossy fiber (MF to CA3 synapses. Whether the defect is specific to certain inputs or postsynaptic targets in CA3 is unknown. To determine this, we performed whole-cell recording from pyramidal cells (PYR and the stratum lucidum (SL interneurons in the CA3, both of which receive excitatory MF terminals with high levels of BACE1 expression. BACE1 KOs displayed an enhancement of paired-pulse facilitation at the MF inputs to CA3 PYRs without changes at the MF inputs to SL interneurons, which suggests postsynaptic target specific regulation. The synaptic dysfunction in CA3 PYRs was not restricted to excitatory synapses, as seen by an increase in the paired-pulse ratio of evoked inhibitory postsynaptic currents from SL to CA3 PYRs. In addition to the changes in evoked synaptic transmission, BACE1 KOs displayed a reduction in the frequency of miniature excitatory and inhibitory postsynaptic currents (mEPSCs and mIPSCs in CA3 PYRs without alteration in mEPSCs recorded from SL interneurons. This suggests that the impairment may be more global across diverse inputs to CA3 PYRs. Our results indicate that the synaptic dysfunctions seen in BACE1 KOs are specific to the postsynaptic target, the CA3 PYRs, independent of the input type.

  10. Postsynaptic target specific synaptic dysfunctions in the CA3 area of BACE1 knockout mice.

    Science.gov (United States)

    Wang, Hui; Megill, Andrea; Wong, Philip C; Kirkwood, Alfredo; Lee, Hey-Kyoung

    2014-01-01

    Beta-amyloid precursor protein cleaving enzyme 1 (BACE1), a major neuronal β-secretase critical for the formation of β-amyloid (Aβ) peptide, is considered one of the key therapeutic targets that can prevent the progression of Alzheimer's disease (AD). Although a complete ablation of BACE1 gene prevents Aβ formation, we previously reported that BACE1 knockouts (KOs) display presynaptic deficits, especially at the mossy fiber (MF) to CA3 synapses. Whether the defect is specific to certain inputs or postsynaptic targets in CA3 is unknown. To determine this, we performed whole-cell recording from pyramidal cells (PYR) and the stratum lucidum (SL) interneurons in the CA3, both of which receive excitatory MF terminals with high levels of BACE1 expression. BACE1 KOs displayed an enhancement of paired-pulse facilitation at the MF inputs to CA3 PYRs without changes at the MF inputs to SL interneurons, which suggests postsynaptic target specific regulation. The synaptic dysfunction in CA3 PYRs was not restricted to excitatory synapses, as seen by an increase in the paired-pulse ratio of evoked inhibitory postsynaptic currents from SL to CA3 PYRs. In addition to the changes in evoked synaptic transmission, BACE1 KOs displayed a reduction in the frequency of miniature excitatory and inhibitory postsynaptic currents (mEPSCs and mIPSCs) in CA3 PYRs without alteration in mEPSCs recorded from SL interneurons. This suggests that the impairment may be more global across diverse inputs to CA3 PYRs. Our results indicate that the synaptic dysfunctions seen in BACE1 KOs are specific to the postsynaptic target, the CA3 PYRs, independent of the input type.

  11. Jazz drummers recruit language-specific areas for the processing of rhythmic structure.

    Science.gov (United States)

    Herdener, Marcus; Humbel, Thierry; Esposito, Fabrizio; Habermeyer, Benedikt; Cattapan-Ludewig, Katja; Seifritz, Erich

    2014-03-01

    Rhythm is a central characteristic of music and speech, the most important domains of human communication using acoustic signals. Here, we investigated how rhythmical patterns in music are processed in the human brain, and, in addition, evaluated the impact of musical training on rhythm processing. Using fMRI, we found that deviations from a rule-based regular rhythmic structure activated the left planum temporale together with Broca's area and its right-hemispheric homolog across subjects, that is, a network also crucially involved in the processing of harmonic structure in music and the syntactic analysis of language. Comparing the BOLD responses to rhythmic variations between professional jazz drummers and musical laypersons, we found that only highly trained rhythmic experts show additional activity in left-hemispheric supramarginal gyrus, a higher-order region involved in processing of linguistic syntax. This suggests an additional functional recruitment of brain areas usually dedicated to complex linguistic syntax processing for the analysis of rhythmical patterns only in professional jazz drummers, who are especially trained to use rhythmical cues for communication.

  12. TRANSIT THROUGH THE SCHENGEN AREA FOR THE HOLDERS OF SPECIFIC SWISS DOCUMENTS

    CERN Multimedia

    2006-01-01

    The Swiss Permanent Mission has informed CERN of the following relaxation of the transit regulations granted by the States applying the Schengen Agreement and other European States to third-country nationals who are normally required to obtain a visa. As from 10 July 2006, those holding a Carte de légitimation or Attestation de fonctions issued by the Swiss Federal Department of Foreign Affairs or a B, C or Ci-type residence permit are exempted from the requirement to obtain a visa for transit through the Schengen area, so long as the transit period does not exceed five days (for each transit). For other circumstances (for example tourism, including for conferences), the requirement to obtain a visa remains in force. The States that form the Schengen area are: Austria, Belgium, Denmark, Finland, France, Germany, Greece, Iceland, Italy, Luxembourg, Norway, the Netherlands, Portugal, Spain and Sweden. In addition, the following States have decided to apply the same exemption from the requirement to obtain a...

  13. Energy spectrum and specific heat of two-dimensional electron systems with spin-orbit interaction in a magnetic field parallel to the conducting layer

    Science.gov (United States)

    Shevchenko, O. S.; Kopeliovich, A. I.

    2016-03-01

    The energy spectrum of a quasi-two-dimensional electron gas in an in-plane magnetic field is studied using the perturbation theory and quasiclassical approach in the presence of the Rashba and Dresselhaus spin-orbit coupling. The existence of the intersection of energy sublevels in electron spectrum is demonstrated. The reciprocal mass tensor of electrons is analyzed. The heat capacity of the degenerate electron gas is examined, and its relations with the key features of the spectrum are shown.

  14. Pressure load on specific body areas of gestating sows lying on rubber mats with different softness.

    Science.gov (United States)

    Schubbert, A; Hartung, E; Schrader, L

    2014-08-01

    Rubber mats offer a possibility to increase lying comfort for sows with positive effects on sow lying behavior and health. However, until now, no information has been reported about the relationship between the softness of rubber mats and the pressure load on certain body areas of sows. We used a total of 68 (40 multiparous, 28 primiparous) German Landrace × German Landrace sows with a BW within the range of 90 to 330 kg (divided in 3 weight classes) to measure peak force and distribution of pressure during lying in the sternal and half recumbent position. Measures were done in an experimental pen that was equipped with a pressure sensor map system (5400 NTL; Tekscan Inc., Boston, MA). Three rubber mats differing in softness (penetration depth: hard mat, 4.0 mm [HM]; soft mat, 14.6 mm [SM]; very soft mat, 43.0 mm [VSM]) were tested and compared to concrete floor (CF) as a reference. Pressure load was analyzed in the sternal position for the sternum, belly, and ham body regions and also in the half recumbent position for the shoulder. For each lying position we determined the body region with the highest pressure load and analyzed the peak force (PF) and the contact area (CA) using a mixed model ANOVA (MIXED procedure of SAS Enterprise, version 4.3., SAS Inst. Inc., Cary, NC) with floor type, weight class of sows, and their interaction as fixed factors. Overall, the highest values for PF in the sternal position were found on the sternum (median: 1.62 N/cm(2)) and in the half recumbent position on the shoulder (median: 2.72 N/cm(2)). In the sternal position PF on the sternum was lower on VSM compared to CF (P = 0.001). In the half-recumbent position PF on the shoulder was lower on VSM compared to CF (P = 0.013) and compared to HM (P = 0.011). The weight of the sows affected PF on the sternum in the sternal position, with lower values in weight class 1 compared to weight class 2 (P = 0.001) and weight class 3 (P = 0.002). Contact area under the sternum was larger on

  15. Beyond breeding area management: Population specific migration patterns of a European-Afrotropical songbird

    DEFF Research Database (Denmark)

    Pedersen, Lykke; Tøttrup, Anders P.; Thorup, Kasper

    species migration systems is thus still limited. In this study, we analysed the spatio-temporal migration schedule of Red-backed Shrikes, Lanius collurio, using tracking data from individuals originating from geographically distinct breeding populations (Scandinavia, the Netherlands, Spain and Greece......Every year, billions of songbirds migrate thousands of kilometres between their European breeding grounds and African overwintering area. As migratory birds are dependent on resources at a number of sites varying in both space and time, they are likely to be more vulnerable to environmental change....... Perhaps as a consequence, long-distance migratory songbirds are declining rapidly compared to their sedentary counterparts. To understand what is driving these declines in European-Afrotropical migratory bird populations we need to understand the full annual migration cycle of these birds. Recent...

  16. Area specific stripping factors for AGS. A method for extracting stripping factors from survey data

    Energy Technology Data Exchange (ETDEWEB)

    Aage, H.K.; Korsbech, U. [Technical Univ. of Denmark (Denmark)

    2006-04-15

    In order to use Airborne Gamma-ray Spectrometry (AGS) for contamination mapping, for source search etc. one must to be able to eliminate the contribution to the spectra from natural radioactivity. This in general is done by a stripping technique. The parameters for performing a stripping have until recently been measured by recording gamma spectra at special calibration sites (pads). This may be cumbersome and the parameters may not be correct when used at low gamma energies for environmental spectra. During 2000-2001 DTU tested with success a new technique for Carborne Gamma-ray Spectrometry (CGS) where the spectra from the surveyed area (or from a similar area) were used for calculating the stripping parameters. It was possible to calculate usable stripping ratios for a number of low energy windows - and weak source signals not detectable by other means were discovered with the ASS technique. In this report it is shown that the ASS technique also works for AGS data, and it has been used for recent Danish AGS tests with point sources. (Check of calibration of AGS parameters.) By using the ASS technique with the Boden data (Barents Rescue) an exercise source was detected that has not been detected by any of the teams during the exercise. The ASS technique therefore seems to be better for search for radiation anomalies than any other method known presently. The experiences also tell that although the stripping can be performed correctly at any altitude there is a variation of the stripping parameters with altitude that has not yet been quite understood. However, even with the oddly variations the stripping worked as expected. It was also observed that one might calculate a single common set of usable stripping factors for all altitudes from the entire data set i.e. some average a, b and c values. When those stripping factors were used the stripping technique still worked well. (au)

  17. Snow specific surface area simulation using the one-layer snow model in the Canadian LAnd Surface Scheme (CLASS)

    OpenAIRE

    2013-01-01

    Snow grain size is a key parameter for modeling microwave snow emission properties and the surface energy balance because of its influence on the snow albedo, thermal conductivity and diffusivity. A model of the specific surface area (SSA) of snow was implemented in the one-layer snow model in the Canadian LAnd Surface Scheme (CLASS) version 3.4. This offline multilayer model (CLASS-SSA) simulates the decrease of SSA based on snow age, snow temperature and t...

  18. Neuron-type-specific signals for reward and punishment in the ventral tegmental area.

    Science.gov (United States)

    Cohen, Jeremiah Y; Haesler, Sebastian; Vong, Linh; Lowell, Bradford B; Uchida, Naoshige

    2012-01-18

    Dopamine has a central role in motivation and reward. Dopaminergic neurons in the ventral tegmental area (VTA) signal the discrepancy between expected and actual rewards (that is, reward prediction error), but how they compute such signals is unknown. We recorded the activity of VTA neurons while mice associated different odour cues with appetitive and aversive outcomes. We found three types of neuron based on responses to odours and outcomes: approximately half of the neurons (type I, 52%) showed phasic excitation after reward-predicting odours and rewards in a manner consistent with reward prediction error coding; the other half of neurons showed persistent activity during the delay between odour and outcome that was modulated positively (type II, 31%) or negatively (type III, 18%) by the value of outcomes. Whereas the activity of type I neurons was sensitive to actual outcomes (that is, when the reward was delivered as expected compared to when it was unexpectedly omitted), the activity of type II and type III neurons was determined predominantly by reward-predicting odours. We 'tagged' dopaminergic and GABAergic neurons with the light-sensitive protein channelrhodopsin-2 and identified them based on their responses to optical stimulation while recording. All identified dopaminergic neurons were of type I and all GABAergic neurons were of type II. These results show that VTA GABAergic neurons signal expected reward, a key variable for dopaminergic neurons to calculate reward prediction error.

  19. Do children with specific language impairment and autism spectrum disorders benefit from the presence of orthography when learning new spoken words?

    Science.gov (United States)

    Ricketts, Jessie; Dockrell, Julie E; Patel, Nita; Charman, Tony; Lindsay, Geoff

    2015-06-01

    This experiment investigated whether children with specific language impairment (SLI), children with autism spectrum disorders (ASD), and typically developing children benefit from the incidental presence of orthography when learning new oral vocabulary items. Children with SLI, children with ASD, and typically developing children (n=27 per group) between 8 and 13 years of age were matched in triplets for age and nonverbal reasoning. Participants were taught 12 mappings between novel phonological strings and referents; half of these mappings were trained with orthography present and half were trained with orthography absent. Groups did not differ on the ability to learn new oral vocabulary, although there was some indication that children with ASD were slower than controls to identify newly learned items. During training, the ASD, SLI, and typically developing groups benefited from orthography to the same extent. In supplementary analyses, children with SLI were matched in pairs to an additional control group of younger typically developing children for nonword reading. Compared with younger controls, children with SLI showed equivalent oral vocabulary acquisition and benefit from orthography during training. Our findings are consistent with current theoretical accounts of how lexical entries are acquired and replicate previous studies that have shown orthographic facilitation for vocabulary acquisition in typically developing children and children with ASD. We demonstrate this effect in SLI for the first time. The study provides evidence that the presence of orthographic cues can support oral vocabulary acquisition, motivating intervention approaches (as well as standard classroom teaching) that emphasize the orthographic form.

  20. Optimization of operating variables for production of ultra-fine talc in a stirred mill. Specific surface area investigations

    Directory of Open Access Journals (Sweden)

    Toraman Oner Yusuf

    2016-01-01

    Full Text Available Due to its properties such as chemical inertness, softness, whiteness, high thermal conductivity, low electrical conductivity and adsorption properties talc has wide industrial applications in paper, cosmetics, paints, polymer, ceramics, refractory materials and pharmaceutical. The demand for ultra-fine talc is emerging which drives the mineral industry to produce value added products. In this study, it was investigated how certain grinding parameters such as mill speed, ball filling ratio, powder filling ratio and grinding time of dry stirred mill affect grindability of talc ore (d97=127 μm. A series of laboratory experiments using a 24 full factorial design was conducted to determine the optimal operational parameters of a stirred mill in order to minimize the specific surface area. The main and interaction effects on the volume specific surface area (SV, m2.cm−3 of the ground product were evaluated using the Yates analysis. Under the optimal conditions at the stirrer speed of 600 rpm, grinding time of 20 min, sample mass of 5% and ball ratio of 70%, the resulting talc powder had larger volume specific surface area (i.e., 3.48 m2.cm−3 than the starting material (i.e., 1.84 m2.cm−3.

  1. Adolescent and young adult medicine is a special and specific area of medical practice.

    Science.gov (United States)

    Steinbeck, Kate; Towns, Susan; Bennett, David

    2014-06-01

    Adolescent and young adult medicine is a concept that has gained traction in the last decade or so. The medical literature has come primarily from oncology. Advances in neuroscience that document continuing brain development into the third decade, and research that shows risk behaviours associated with adolescence both remain and may increase in the third decade, have been two of the drivers in the conversation around linking these two age groups together as a medical practice group. A third driver of importance is transition care in chronic illness, where older adolescents and young adults continue to have difficulties making effective linkages with adult care. The case for specific training in adolescent and young adult medicine, including the developmental concepts behind it, the benefits of the delineation and the particular challenges in the Australian health-care system, are discussed. On balance, there is a strong case for managing the health issues of adolescents and young adults together. This scenario does not fit easily with the age demarcations that are in place in acute care facilities. However, this is less the case in community services and can work in focused private practice. Such a situation suggests that both paediatric and adult physicians might be interested in adolescent and young adult medicine training and practice.

  2. Site-specific landslide assessment in Alpine area using a reliable integrated monitoring system

    Science.gov (United States)

    Romeo, Saverio; Di Matteo, Lucio; Kieffer, Daniel Scott

    2016-04-01

    Rockfalls are one of major cause of landslide fatalities around the world. The present work discusses the reliability of integrated monitoring of displacements in a rockfall within the Alpine region (Salzburg Land - Austria), taking into account also the effect of the ongoing climate change. Due to the unpredictability of the frequency and magnitude, that threatens human lives and infrastructure, frequently it is necessary to implement an efficient monitoring system. For this reason, during the last decades, integrated monitoring systems of unstable slopes were widely developed and used (e.g., extensometers, cameras, remote sensing, etc.). In this framework, Remote Sensing techniques, such as GBInSAR technique (Groung-Based Interferometric Synthetic Aperture Radar), have emerged as efficient and powerful tools for deformation monitoring. GBInSAR measurements can be useful to achieve an early warning system using surface deformation parameters as ground displacement or inverse velocity (for semi-empirical forecasting methods). In order to check the reliability of GBInSAR and to monitor the evolution of landslide, it is very important to integrate different techniques. Indeed, a multi-instrumental approach is essential to investigate movements both in surface and in depth and the use of different monitoring techniques allows to perform a cross analysis of the data and to minimize errors, to check the data quality and to improve the monitoring system. During 2013, an intense and complete monitoring campaign has been conducted on the Ingelsberg landslide. By analyzing both historical temperature series (HISTALP) recorded during the last century and those from local weather stations, temperature values (Autumn-Winter, Winter and Spring) are clearly increased in Bad Hofgastein area as well as in Alpine region. As consequence, in the last decades the rockfall events have been shifted from spring to summer due to warmer winters. It is interesting to point out that

  3. A sex-specific association of common variants of neuroligin genes (NLGN3 and NLGN4X with autism spectrum disorders in a Chinese Han cohort

    Directory of Open Access Journals (Sweden)

    Li Hui

    2011-05-01

    Full Text Available Abstract Background Synaptic genes, NLGN3 and NLGN4X, two homologous members of the neuroligin family, have been supposed as predisposition loci for autism spectrum disorders (ASDs, and defects of these two genes have been identified in a small fraction of individuals with ASDs. But no such rare variant in these two genes has as yet been adequately replicated in Chinese population and no common variant has been further investigated to be associated with ASDs. Methods 7 known ASDs-related rare variants in NLGN3 and NLGN4X genes were screened for replication of the initial findings and 12 intronic tagging single nucleotide polymorphisms (SNPs were genotyped for case-control association analysis in a total of 229 ASDs cases and 184 control individuals in a Chinese Han cohort, using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF mass spectrometry. Results We found that a common intronic variant, SNP rs4844285 in NLGN3 gene, and a specific 3-marker haplotype XA-XG-XT (rs11795613-rs4844285-rs4844286 containing this individual SNP were associated with ASDs and showed a male bias, even after correction for multiple testing (SNP allele: P = 0.048, haplotype:P = 0.032. Simultaneously, none of these 7 known rare mutation of NLGN3 and NLGN4X genes was identified, neither in our patients with ASDs nor controls, giving further evidence that these known rare variants might be not enriched in Chinese Han cohort. Conclusion The present study provides initial evidence that a common variant in NLGN3 gene may play a role in the etiology of ASDs among affected males in Chinese Han population, and further supports the hypothesis that defect of synapse might involvement in the pathophysiology of ASDs.

  4. Theory of Mind and Emotion Recognition Skills in Children with Specific Language Impairment, Autism Spectrum Disorder and Typical Development: Group Differences and Connection to Knowledge of Grammatical Morphology, Word-Finding Abilities and Verbal Working Memory

    Science.gov (United States)

    Loukusa, Soile; Mäkinen, Leena; Kuusikko-Gauffin, Sanna; Ebeling, Hanna; Moilanen, Irma

    2014-01-01

    Background: Social perception skills, such as understanding the mind and emotions of others, affect children's communication abilities in real-life situations. In addition to autism spectrum disorder (ASD), there is increasing knowledge that children with specific language impairment (SLI) also demonstrate difficulties in their social…

  5. Sex-differential and non-specific effects of routine vaccinations in a rural area with low vaccination coverage

    DEFF Research Database (Denmark)

    Aaby, Peter; Nielsen, Jens; Benn, Christine Stabell;

    2015-01-01

    BACKGROUND: We examined the potential sex-differential and non-specific effects of bacille Calmette-Guérin (BCG), diphtheria-tetanus-pertussis (DTP) and measles vaccine (MV) in a rural area of Senegal. METHODS: The 4133 children born in the area between 1996 and 1999 were included in the study.......006). Children who had received DTP simultaneously with MV or DTP after MV had significantly higher mortality (MRR=2.59 [1.32-5.07]) compared with children having MV-only as their most recent vaccination. After 9 months, the female-male MRR was 0.61 (0.31-1.19) for measles-vaccinated children but remained 1.......54 (1.03-2.31) for DTP-vaccinated children who had not received MV (p=0.01). CONCLUSIONS: The sequence of routine vaccinations is important for the overall impact on child survival and these vaccines are associated with sex-differential effects....

  6. Parasite-specific lactate dehydrogenase for the diagnosis of Plasmodium falciparum infection in an endemic area in west Uganda.

    Science.gov (United States)

    Jelinek, T; Kilian, A H; Henk, M; Mughusu, E B; Nothdurft, H D; Löscher, T; Knobloch, J; Van Sonnenburg, F

    1996-04-01

    The measurement of parasite lactate dehydrogenase (pLDH) has been presented as an easy and rapid method for the diagnosis of malaria in humans. In order to evaluate the sensitivity and specificity of such a test we examined blood samples from 429 Ugandan patients. While pLDH activity was significantly linked to parasitaemia, sensitivity and specificity were found to be rather low at 58.8 and 62.2% respectively. The positive and negative predictive values failed to meet necessary standards. We conclude that the methods of measurement of pLDH activity in malaria infection, although potentially useful for the fast diagnosis of malaria, need to be improved to be of true value in endemic areas.

  7. Improved Cellulose Adsorption Method for the Preparation of Perovskite Oxides with Large Specific Surface Area at Low Temperature

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Perovskite-type La1-xSrxMO3-d (x=0,0.1,0.2, B=Co,Fe,Mn) oxides were prepared by pyrolysis of metal salt-(organic acid)-cellulose compound precursors. Low calcination temperatures, usually lower than 600oC, were needed. The specific surface area of the as-prepared oxides is higher than that prepared by the cellulose adsorption method, and is comparable to that prepared by sol-gel method. The effective organic acid could be EDTA acid, citric acid or DL-hydroxysuccinic acid, among them, EDTA acid is the best one.

  8. Relationship between Serum Specific IgE and Allergen Skin Test in Allergic Patients of Wuhan Area

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    In order to study the relationship between serum specific IgE (sIgE) and allergen skin test, allergen skin tests and detections of sIgE in 220 allergic patients of Wuhan area were analyzed.The coherent rate of the two methods was beyond 70 % (P<0.01). It was concluded that the in vitro and in vivo detection methods of allergens have a high coherence and can be used as the effective ways to diagnose the allergic diseases in clinical practice.

  9. Tree mortality across biomes is promoted by drought intensity, lower wood density and higher specific leaf area.

    Science.gov (United States)

    Greenwood, Sarah; Ruiz-Benito, Paloma; Martínez-Vilalta, Jordi; Lloret, Francisco; Kitzberger, Thomas; Allen, Craig D; Fensham, Rod; Laughlin, Daniel C; Kattge, Jens; Bönisch, Gerhard; Kraft, Nathan J B; Jump, Alistair S

    2017-04-01

    Drought events are increasing globally, and reports of consequent forest mortality are widespread. However, due to a lack of a quantitative global synthesis, it is still not clear whether drought-induced mortality rates differ among global biomes and whether functional traits influence the risk of drought-induced mortality. To address these uncertainties, we performed a global meta-analysis of 58 studies of drought-induced forest mortality. Mortality rates were modelled as a function of drought, temperature, biomes, phylogenetic and functional groups and functional traits. We identified a consistent global-scale response, where mortality increased with drought severity [log mortality (trees trees(-1)  year(-1) ) increased 0.46 (95% CI = 0.2-0.7) with one SPEI unit drought intensity]. We found no significant differences in the magnitude of the response depending on forest biomes or between angiosperms and gymnosperms or evergreen and deciduous tree species. Functional traits explained some of the variation in drought responses between species (i.e. increased from 30 to 37% when wood density and specific leaf area were included). Tree species with denser wood and lower specific leaf area showed lower mortality responses. Our results illustrate the value of functional traits for understanding patterns of drought-induced tree mortality and suggest that mortality could become increasingly widespread in the future.

  10. When does this cortical area drop off? Principal component structuring of the EEG spectrum yields yes-or-no criteria of local sleep onset.

    Science.gov (United States)

    Putilov, Arcady A

    2014-06-22

    The traditional sleep scoring approach has been invented long before the recognition of strictly local nature of the sleep process. It considers sleep as a whole-organism behavior state, and, thus, it cannot be used for identification of sleep onset in a separate brain region. Therefore, this paper was aimed on testing whether the practically useful, simple and reliable yes-or-no criterion of sleep onset in a particular cortical region might be developed through applying principal component analysis to the electroencephalographic (EEG) spectra. The resting EEG was recorded with 2-hour intervals throughout 43-61-hour prolongation of wakefulness, and during 12 20-minute attempts to nap in the course of 24-hour wakefulness (15 and 18 adults, respectively). The EEG power spectra were averaged on 1-min intervals of each resting EEG record and on 1-min intervals of each napping attempt, respectively. Since we earlier demonstrated that scores on the first and second principal components of the EEG spectrum exhibit dramatic changes during the sleep onset period, a zero-crossing buildup of the first score and a zero-crossing decline of the second score were examined as possible yes-or-no markers of regional sleep onsets. The results suggest that, irrespective of electrode location, sleep onset criterion and duration of preceding wakefulness, a highly significant zero-crossing decline of the second principal component score always occurred within 1-minute interval of transition from wakefulness to sleep. Therefore, it was concluded that such zero-crossing decline can serve as a reliable, simple, and practically useful yes-or-no marker of drop off event in a given cortical area.

  11. [Response characteristics of the field-measured spectrum for the four general types of halophyte and species recognition in the northern slope area of Tianshan Mountain in Xinjiang].

    Science.gov (United States)

    Zhang, Fang; Xiong, Hei-gang; Nurbay, Abdusalih; Luan, Fu-ming

    2011-12-01

    Based on the field-measured Vis-NIR reflectance of four common types of halophyte (Achnatherum splendens(Trin.) Nevski, Sophora alopecuroides L., Camphorosma monspeliaca L. subsp. lessingii(L.)Aellen, Alhagi sparsifolia shap) within given spots in the Northern Slope Area of Tianshan Mountain in Xinjiang, the spectral response characteristics and species recognition of these types of halophyte were analyzed. The results showed that (Alhagi sparsifolia shap) had higher chlorophyll and carotenoid by CARI and SIPI index. (Sophora alopecuroides L. was at a vigorously growing state and had a higher NDVI compared with the other three types of halophyte because of its greater canopy density. But its CARI and SIPI values were lower due to the influence of its flowers. (Sophora alopecuroides L.) and (Camphorosma monspeliaca L. subsp. lessingii(L.)) had stable REPs and BEPs, but REPs and BEPs of (Achnatherum splendens(Trin.)Nevski, Aellen, Alhagi sparsifolia shap) whose spectra red shift and spectra blue shift occurred concurrently obviously changed. There was little difference in spectral curves among the four types of halophyte, so the spectrum mixing phenomenon was severe. (Camphorosma monspeliaca L. subsp. lessingii (L.)Aellen) and (Alhagi sparsifolia shap) could not be separated exactly in a usual R/NIR feature space in remote sensing. Using the stepwise discriminant analysis, five indices were selected to establish the discriminant model, and the model accuracy was discussed using the validated sample group. The total accuracy of the discriminant model was above 92% and (Achnatherum splendens(Trin.)Nevski) and (Camphorosma monspeliaca L. subsp. lessingii(L.)Aellen) could be respectively recognized 100% correctly.

  12. Determination of the volume-specific surface area by using transmission electron tomography for characterization and definition of nanomaterials

    Directory of Open Access Journals (Sweden)

    Francisco Michel

    2011-05-01

    Full Text Available Abstract Background Transmission electron microscopy (TEM remains an important technique to investigate the size, shape and surface characteristics of particles at the nanometer scale. Resulting micrographs are two dimensional projections of objects and their interpretation can be difficult. Recently, electron tomography (ET is increasingly used to reveal the morphology of nanomaterials (NM in 3D. In this study, we examined the feasibility to visualize and measure silica and gold NM in suspension using conventional bright field electron tomography. Results The general morphology of gold and silica NM was visualized in 3D by conventional TEM in bright field mode. In orthoslices of the examined NM the surface features of a NM could be seen and measured without interference of higher or lower lying structures inherent to conventional TEM. Segmentation by isosurface rendering allowed visualizing the 3D information of an electron tomographic reconstruction in greater detail than digital slicing. From the 3D reconstructions, the surface area and the volume of the examined NM could be estimated directly and the volume-specific surface area (VSSA was calculated. The mean VSSA of all examined NM was significantly larger than the threshold of 60 m2/cm3. The high correlation between the measured values of area and volume gold nanoparticles with a known spherical morphology and the areas and volumes calculated from the equivalent circle diameter (ECD of projected nanoparticles (NP indicates that the values measured from electron tomographic reconstructions are valid for these gold particles. Conclusion The characterization and definition of the examined gold and silica NM can benefit from application of conventional bright field electron tomography: the NM can be visualized in 3D, while surface features and the VSSA can be measured.

  13. Estimasi kebutuhan spektrum untuk memenuhi target rencana pita lebar Indonesia di wilayah perkotaan [The estimation of spectrum requirements to meet the target of Indonesia broadband plan in urban area

    Directory of Open Access Journals (Sweden)

    Kasmad Ariansyah

    2015-12-01

    Full Text Available Pemerintah Indonesia telah mengesahkan Rencana Pita Lebar Indonesia menjelang akhir tahun 2014. Dokumen tersebut berisi panduan dan arah pembangunan pita lebar nasional dan berisi berisi target-target pencapaian berkelanjutan antara tahun 2014-2019. Terkait target capaian pita lebar nirkabel, ketersediaan dan kecukupan spektrum frekuensi merupakan salah satu hal yang sangat penting.  Studi ini dilakukan untuk mengestimasi kebutuhan spektrum frekuensi dalam rangka memenuhi target capaian Rencana Pita Lebar Indonesia khususnya layanan pita lebar nirkabel di wilayah perkotaan. DKI Jakarta dipilih sebagai sampel wilayah perkotaan. Analisis dilakukan dengan menghitung luas cakupan BTS, mengestimasi jumlah potensi pengguna, mengestimasi kebutuhan spektrum dan membandingkannya dengan spektrum yang sudah dialokasikan untuk mendapatkan jumlah kekurangan spektrum. 3G dan 4G diasumsikan sebagai teknologi yang digunakan untuk memenuhi sasaran pita lebar bergerak. Hasil analisis menunjukkan pada rentang tahun 2016-2019 akan terjadi kekurangan spektrum di wilayah perkotaan sebesar 2x234,5 MHz sampai dengan 2x240,5MHz (untuk mode FDD atau sebesar 313 MHz sampai dengan 321 MHz (untuk mode TDD. Spektrum frekuensi merupakan sumber daya yang reusable, dengan mengasumsikan kebutuhan spektrum di perdesaan lebih rendah dibanding kebutuhan di perkotaan, maka estimasi ini dapat pula digunakan untuk menggambarkan kebutuhan spektrum di Indonesia secara keseluruhan.*****Indonesian government has issued Indonesia Broadband Plan (IBP at the end of 2014. IBP provides guidance and direction for the development of national broadband and contains targets in the period of 2014 to 2019. Relating to wireless broadband target, the availability and the adequacy of spectrum is very important. This study was conducted to estimate the spectrum requirements to meet the Indonesia broadband plan target especially the target of mobile broadband in urban area. DKI Jakarta was taken as

  14. Natural radioactivity measurements in agricultural soil, fertilizer and crops in some specific areas of Kingdom of Saudi Arabia

    Energy Technology Data Exchange (ETDEWEB)

    Latif, Shaikh Abdul; Kinsara, Abdulraheem Abdulrahman; Molla, Nurul Islam; Nassef, Mohamed Hamed [King Abdulaziz Univ., Jeddah (Saudi Arabia). Faculty of Engineering

    2014-09-01

    High Purity Germanium (HPGe) detector gamma-ray spectrometry with 500 cc Marinelli beaker geometry was used for radioactivity measurement in some specific areas of Kingdom of Saudi Arabia (KSA). The detection limits of {sup 210}Pb, {sup 238}U, {sup 226}Ra, {sup 232}Th and {sup 40}K in soil, fertilizers, and vegetables lie mostly below 1 Bq/kg. The activity concentrations of {sup 238}U and {sup 226}Ra in local phosphate fertilizers were measured in the range of 236.8-879.0 Bq/kg and 101.5-297.0 Bq/kg, respectively. The respective activity concentrations of {sup 238}U and {sup 226}Ra measured in one charge of German phosphate fertilizer are in the range of 552.7-790.0 Bq/kg and 280.6-317.0 Bq/kg. The activity concentrations of {sup 232}Th are assessed to have maximum values up to 2.24 Bq/kg in locally manufactured phosphate fertilizers. Local urea exhibited concentration level (Bq/kg) of {sup 210}Pb, {sup 238}U, {sup 226}Ra, {sup 232}Th and {sup 40}K below the detection limit. Mean values of activity concentrations of {sup 238}U in agricultural soil of Wadi Fatima, Taif, Hada Al-Sham, Madina City and Abyar Al-MashiMadina are 21.7 ± 3.24, 38.2 ± 4.1, 17.6 ± 2.1, 34.3 ± 3.5 and 32.7 ± 2.4 Bq/kg, respectively. The respective mean of {sup 226}Ra activity concentrations in those areas are 12.16 ± 1.16, 20.2 ± 1.33, 11.21 ± 0.4, 21.4 ± 1.7 and 21.0 ± 1.22 Bq/kg. The specific activity of {sup 232}Th in the respective areas has been measured as 12.6 ± 1.3, 25.3 ± 0.8, 11.5 ± 0.9, 20.4 ± 2.4 and 20.0 ± 1.2 Bq/kg. Activity concentrations of {sup 210}Pb, {sup 238}U, {sup 226}Ra and {sup 232}Th in the vegetable samples are mostly found in the range of 0.37 Bq/kg to 37.8 Bq/kg. The {sup 40}K specific activity lies in the range of 44.4-196 Bq/kg. The calculated absorbed dose rates in the representative locations are 24.07-53.28 nGy/h. (orig.)

  15. Immunological characterization and transcription profiling of peripheral blood (PB monocytes in children with autism spectrum disorders (ASD and specific polysaccharide antibody deficiency (SPAD: case study

    Directory of Open Access Journals (Sweden)

    Jyonouchi Harumi

    2012-01-01

    Full Text Available Abstract Introduction There exists a small subset of children with autism spectrum disorders (ASD characterized by fluctuating behavioral symptoms and cognitive skills following immune insults. Some of these children also exhibit specific polysaccharide antibody deficiency (SPAD, resulting in frequent infection caused by encapsulated organisms, and they often require supplemental intravenous immunoglobulin (IVIG (ASD/SPAD. This study assessed whether these ASD/SPAD children have distinct immunological findings in comparison with ASD/non-SPAD or non-ASD/SPAD children. Case description We describe 8 ASD/SPAD children with worsening behavioral symptoms/cognitive skills that are triggered by immune insults. These ASD/SPAD children exhibited delayed type food allergy (5/8, treatment-resistant seizure disorders (4/8, and chronic gastrointestinal (GI symptoms (5/8 at high frequencies. Control subjects included ASD children without SPAD (N = 39, normal controls (N = 37, and non-ASD children with SPAD (N = 12. Discussion and Evaluation We assessed their innate and adaptive immune responses, by measuring the production of pro-inflammatory and counter-regulatory cytokines by peripheral blood mononuclear cells (PBMCs in responses to agonists of toll like receptors (TLR, stimuli of innate immunity, and T cell stimulants. Transcription profiling of PB monocytes was also assessed. ASD/SPAD PBMCs produced less proinflammatory cytokines with agonists of TLR7/8 (IL-6, IL-23, TLR2/6 (IL-6, TLR4 (IL-12p40, and without stimuli (IL-1ß, IL-6, and TNF-α than normal controls. In addition, cytokine production of ASD/SPAD PBMCs in response to T cell mitogens (IFN-γ, IL-17, and IL-12p40 and candida antigen (Ag (IL-10, IL-12p40 were less than normal controls. ASD/non-SPAD PBMDs revealed similar results as normal controls, while non-ASD/SPAD PBMCs revealed lower production of IL-6, IL-10 and IL-23 with a TLR4 agonist. Only common features observed between ASD/SPAD and non

  16. Low temperature leaf photosynthesis of a Miscanthus germplasm collection correlates positively to shoot growth rate and specific leaf area

    DEFF Research Database (Denmark)

    Jiao, Xiurong; Sørensen, Kirsten Kørup; Andersen, Mathias Neumann

    2016-01-01

    were selected and grown under warm (24 °C) and cold (14 °C) conditions in a controlled environment. Dark-adapted chlorophyll fluorescence, specific leaf area (SLA) and net photosynthetic rate at a photosynthetically active radiation (PAR) of 1000 μmol m–2 s–1 (A1000) were measured. Photosynthetic light...... conditions and A1000 at 14 °C in a climate chamber. When lowering the temperature from 24 to 14 °C, one M. sacchariflorus exhibited significantly higher Asat and maximum photosynthetic rate in the CO2 response curve (Vmax) than other genotypes at 14 °C, except M. × giganteus ‘Hornum’. Several genotypes...... and CO2 response curves were obtained from 11 of the genotypes, and shoot growth rate was measured under field conditions. Key Results A positive linear relationship was found between SLA and light-saturated photosynthesis (Asat) across genotypes, and also between shoot growth rate under cool field...

  17. Site specific isolated nanostructure array formation on a large area by broad ion beam without any mask and resist

    Energy Technology Data Exchange (ETDEWEB)

    Karmakar, Prasanta, E-mail: prasantak@vecc.gov.in [Variable Energy Cyclotron Centre, 1/AF, Bidhannagar, Kolkata 700064 (India); Satpati, Biswarup [Saha Institute of Nuclear Physics, 1/AF, Bidhannagar, Kolkata 700064 (India)

    2014-06-09

    We report the formation of isolated nanostructure arrays on a large area via broad ion beam implantation without the aid of any mask or resist. Desired ions have been implanted at specific locations of the prefabricated silicon ripple or triangular structures by exploiting the variation of local ion impact angles. We have shown that the implantation of Fe ions on an O{sup +} ions induced pre fabricated triangular shaped patterned Si surface results in a self-organized periodic array of striped magnetic nanostructures having several micron length and about 50 nm width arranged with a spacial separation of ∼200 nm. The morphology, composition, crystalline structure, and magnetic property of these nanopatterns have been analyzed using high-resolution cross-sectional transmission electron microscopy and atomic force microscopy. A geometrical model has been proposed to explain the fundamental features of such ion-induced nanopattern structures.

  18. Variation with thermal cycling in microstructure and area specific resistance of a ferritic stainless steel having rough surfaces

    Science.gov (United States)

    Song, Myoung Youp; Mumm, Daniel R.; Song, Jiunn

    2013-03-01

    Crofer22 APU specimens were prepared by grinding with grit 120 and 400 SiC grinding papers, and were then thermally cycled. The variation in oxidation behavior with thermal cycling was then investigated. Observation of microstructures, measurement of area-specific resistance (ASR), analysis of the atomic percentages of the elements by EDX, and XRD analysis were performed. XRD patterns showed that the (Cr, Mn)3O4 spinel phase grew on the surface of the Crofer22 APU samples ground using grit 120. For the samples ground with grit 400, ASR increased as the number of thermal cycles ( n) increased. Plots of ln (ASR/T) vs. 1/ T for the samples ground with grit 400 after n = 4, 20, and 40 exhibited good linearity, and the apparent activation energies were between 73.4 kJ/mole and 82.5 kJ/mole.

  19. Super-energy-saving dewatering method for high-specific-surface-area fuels by using dimethyl ether

    Energy Technology Data Exchange (ETDEWEB)

    Kanda, H. [Central Research Institute for Electric Power Industry, Kanagawa (Japan)

    2008-07-01

    There is a growing need for the economical dewatering of high-specific-surface-area fuels containing large amounts of water, such as coal and sewage sludge. The principle underlying conventional dewatering methods is evaporation of the water content by heating the fuels to a high temperature, but this approach consumes a considerable amount of energy. The Central Research Institute of the Electric Power Industry (CRIEPI) has developed a method for the extraction of this water through the use of dimethyl ether (DME), which liquefies at ordinary temperatures under the influence of a slight pressure. In this method, the water content in the fuel is extracted into the liquefied DME for separation from the fuel. After dewatering, the DME is depressurised, and subsequently vaporised, thereby leaving the separated water. Dewatering with an input energy of only 1109 kJ/kg water under ordinary conditions has been demonstrated theoretically.

  20. Designing area optimized application-specific network-on-chip architectures while providing hard QoS guarantees.

    Directory of Open Access Journals (Sweden)

    Sajid Gul Khawaja

    Full Text Available With the increase of transistors' density, popularity of System on Chip (SoC has increased exponentially. As a communication module for SoC, Network on Chip (NoC framework has been adapted as its backbone. In this paper, we propose a methodology for designing area-optimized application specific NoC while providing hard Quality of Service (QoS guarantees for real time flows. The novelty of the proposed system lies in derivation of a Mixed Integer Linear Programming model which is then used to generate a resource optimal Network on Chip (NoC topology and architecture while considering traffic and QoS requirements. We also present the micro-architectural design features used for enabling traffic and latency guarantees and discuss how the solution adapts for dynamic variations in the application traffic. The paper highlights the effectiveness of proposed method by generating resource efficient NoC solutions for both industrial and benchmark applications. The area-optimized results are generated in few seconds by proposed technique, without resorting to heuristics, even for an application with 48 traffic flows.

  1. SYNTHESIS OF MESOPOROUS TiO2 MATERIALS WITH HIGH SPECIFIC AREA USING INORGANIC ACIDS AS CATALYSTS

    Institute of Scientific and Technical Information of China (English)

    Dan Huang; Guangsheng Luo; Liming Yang; Yujun Wang

    2005-01-01

    This paper presents a synthesis process for preparing mesoporous titanium dioxide materials in the absence of any templates and using inorganic acids as catalysts. Tetrabutyl titanate was used as the precursor at ambient temperature, and four different inorganic acids, i.e., hydrochloric, nitric, sulfuric and phosphoric, were used as catalysts.The as-prepared mesoporous TiO2 materials were characterized by SEM, XRD and nitrogen adsorption/desorption measurements. The influences of different inorganic acids on the properties of TiO2 were discussed and compared in details. Experiments showed that the inorganic acids have significant effects on the surface area, pore volume, pore size,and pore size distribution of the products. The mesoporous TiO2 materials catalyzed by phosphoric acid exhibited the largest specific surface area and largest pore volume with narrow pore size distribution. Vacuum and infrared drying methods tested in the process were found to have subtle impact on the structure of the TiO2 materials prepared.

  2. Study of the nitric acid influence on the production of Ce O{sub 2} with high specific surface area; Estudo da influencia do acido nitrico na obtencao de CeO{sub 2} com alta area superficial especifica

    Energy Technology Data Exchange (ETDEWEB)

    Albanez, Nelma Kunrath; Bressiani, Jose Carlos [Instituto de Pesquisas Energeticas e Nucleares (IPEN), Sao Paulo, SP (Brazil)

    1996-12-31

    The cerium oxide (Ce O{sub 2}) main characteristics for use as catalyst in an exhaust gases purification system are: high specific surface area (approximately 30 m{sup 2}/g after calcination at 800 deg C/ 2 hs), and thermal stability. The Ce O{sub 2} powders obtained by conventional route, i.e., precipitation, and submitted high temperature (800 deg C) heat treatments, showed low specific surface area. In this work nitric acid effects on the Ce O{sub 2} surface area values were investigated. The variables studied were nitric acid concentration, humidity content in the raw material, re pulp after leaching, addition of hydrogen peroxide (H{sub 2} O{sub 2}) and starting material specific surface area. By this process, it was possible to obtain powders with specific surface area larger than 40 m{sup 2}/g, after treatment at 800 deg C during two hours. (author) 8 refs., 3 figs., 1 tab.

  3. Antimicrobial activity of cathelicidins BMAP28, SMAP28, SMAP29, and PMAP23 against Pasteurella multocida is more broad-spectrum than host species specific.

    Science.gov (United States)

    Brogden, Kim A; Nordholm, Gwen; Ackermann, Mark

    2007-01-17

    The antimicrobial activity of linear, cationic alpha-helical peptides from cattle (BMAP28), sheep (SMAP28 and SMAP29), and pigs (PMAP23) were assessed to determine if activity was selective for Pasteurella multocida from a particular animal species or broad-spectrum against all P. multocida tested. The antimicrobial activities of synthetic peptides were determined for P. multocida isolated from cattle (10 isolates), sheep (10 isolates), and pigs (10 isolates) in a broth microdilution assay. All thirty isolates of P. multocida were susceptible to BMAP28 (MICs and MBCs, 1.0-1.9 microM); SMAP28 and SMAP29 (MICs and MBCs, 0.2-0.7 microM); and PMAP23 (MICs and MBCs, 4.3 to > or = 6.8 microM). Overall, the results of this study suggest that synthesized cathelicidins from cattle, sheep, and pigs had broad-spectrum antimicrobial activity against all P. multocida.

  4. [Specific diversity and culicidian nuisance in the villages of N'gatty and Allaba in laguna area of Ivory Coast].

    Science.gov (United States)

    Fofana, D; Konan, K L; Djohan, V; Konan, Y L; Koné, A B; Doannio, J M C; N'goran, K E

    2010-12-01

    Entomological surveys were undertaken between June and December 2006 in N'gatty and Allaba. These villages are located in southern Ivory Coast in a laguna area in Dabou department. In these villages, there are large swampy areas, which have caused the multiplication of anthropophilic Culicidae. Mosquitoes have been collected at preimaginal stage at the time of the larval prospecting and at adult stage through human landing catch. Larval collections have been made using the classic method of "dipping". Larvae have been identified to the genus level. Then, they have been bred in the laboratory to identify adults. Adults collection has been made once a month during three consecutive nights by human landing catch inside houses. Adults have been identified to the specific level. Eight genera of mosquitoes have been collected in these two villages: Aedes, Anopheles, Coquillettidia, Culex, Eretmapodites, Mansonia, Toxorhynchites and Uranotaenia. Twenty-four species have been listed during this stu y. The genus Mansonia is the most predominant with 86% (N = 15,811) and 80% (N = 1,385), respectively, in N'gatty and Allaba. The average biting rate per day varies between N'gatty and Allaba. It is estimated to 308 bites per human per night (b/h/n) in N'gatty and 72 b/h/n in Allaba. In these villages, mosquito nuisance is mainly due to Mansonia with 264 b/h/n and 58 b/h/n, respectively, in N'gatty and Allaba. However, Anopheles gambiae s.l. average rate was 12 b/h/n in N'gatty and 2 b/h/n in Allaba.

  5. Effect of the specific surface area on thermodynamic and kinetic properties of nanoparticle anatase TiO2 in lithium-ion batteries

    Science.gov (United States)

    Madej, Edyta; Klink, Stefan; Schuhmann, Wolfgang; Ventosa, Edgar; La Mantia, Fabio

    2015-11-01

    Anatase TiO2 nanoparticles with a specific surface area of 100 m2 g-1 and 300 m2 g-1 have been investigated as negative insertion electrode material for lithium-ion batteries. Galvanostatic intermittent titration (GITT) and electrochemical impedance spectroscopy (EIS) were used to investigate the effect of the specific surface area on the performance of the material. GITT was performed at C/10 rate, followed by an EIS measurement after each relaxation step. Separation of kinetic and thermodynamic contributions to the overpotential of the phase transformation on Li+ (de-)insertion allowed revealing a dependency of both terms on the specific surface area. The material with higher surface area undergoes intrinsic transformation during the initial cycles affecting the thermodynamics of (de-)insertion while the sample with lower surface area shows large and asymmetric kinetic hindrances. For the material with 15 nm particles, Li+ de-insertion appears to have a higher resistance than lithium insertion.

  6. Global deprivation of brain-derived neurotrophic factor in the CNS reveals an area-specific requirement for dendritic growth.

    Science.gov (United States)

    Rauskolb, Stefanie; Zagrebelsky, Marta; Dreznjak, Anita; Deogracias, Rubén; Matsumoto, Tomoya; Wiese, Stefan; Erne, Beat; Sendtner, Michael; Schaeren-Wiemers, Nicole; Korte, Martin; Barde, Yves-Alain

    2010-02-03

    Although brain-derived neurotrophic factor (BDNF) is linked with an increasing number of conditions causing brain dysfunction, its role in the postnatal CNS has remained difficult to assess. This is because the bdnf-null mutation causes the death of the animals before BDNF levels have reached adult levels. In addition, the anterograde axonal transport of BDNF complicates the interpretation of area-specific gene deletion. The present study describes the generation of a new conditional mouse mutant essentially lacking BDNF throughout the CNS. It shows that BDNF is not essential for prolonged postnatal survival, but that the behavior of such mutant animals is markedly altered. It also reveals that BDNF is not a major survival factor for most CNS neurons and for myelination of their axons. However, it is required for the postnatal growth of the striatum, and single-cell analyses revealed a marked decreased in dendritic complexity and spine density. In contrast, BDNF is dispensable for the growth of the hippocampus and only minimal changes were observed in the dendrites of CA1 pyramidal neurons in mutant animals. Spine density remained unchanged, whereas the proportion of the mushroom-type spine was moderately decreased. In line with these in vivo observations, we found that BDNF markedly promotes the growth of cultured striatal neurons and of their dendrites, but not of those of hippocampal neurons, suggesting that the differential responsiveness to BDNF is part of a neuron-intrinsic program.

  7. Generation of uniform large-area very high frequency plasmas by launching two specific standing waves simultaneously

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Hsin-Liang, E-mail: hlchen@iner.gov.tw; Tu, Yen-Cheng; Hsieh, Cheng-Chang; Lin, Deng-Lain [Physics Division, Institute of Nuclear Energy Research (INER), Longtan, Taoyuan County 32546, Taiwan (China); Leou, Keh-Chyang [Department of Engineering and System Science, National Tsing Hua University, 101, Section 2, Kuang-Fu Road, Hsinchu 30013, Taiwan (China)

    2014-09-14

    With the characteristics of higher electron density and lower ion bombardment energy, large-area VHF (very high frequency) plasma enhanced chemical vapor deposition has become an essential manufacturing equipment to improve the production throughput and efficiency of thin film silicon solar cell. However, the combination of high frequency and large electrodes leads to the so-called standing wave effect causing a serious problem for the deposition uniformity of silicon thin film. In order to address this issue, a technique based on the idea of simultaneously launching two standing waves that possess similar amplitudes and are out of phase by 90° in time and space is proposed in this study. A linear plasma reactor with discharge length of 54 cm is tested with two different frequencies including 60 and 80 MHz. The experimental results show that the proposed technique could effectively improve the non-uniformity of VHF plasmas from >±60% when only one standing wave is applied to <±10% once two specific standing waves are launched at the same time. Moreover, in terms of the reactor configuration adopted in this study, in which the standing wave effect along the much shorter dimension can be ignored, the proposed technique is applicable to different frequencies without the need to alter the number and arrangement of power feeding points.

  8. Influence of stress, temperature and crystal morphology on isothermal densification and specific surface area decrease of new snow

    Directory of Open Access Journals (Sweden)

    S. Schleef

    2014-10-01

    Full Text Available Laboratory-based, experimental data for the microstructural evolution of new snow are scarce, though applications would benefit from a quantitative characterization of the main influences. To this end, we have analyzed the metamorphism and concurrent densification of new snow under isothermal conditions by means of X-ray microtomography and compiled a comprehensive data set of 45 time series. In contrast to previous measurements on isothermal metamorphism on time scales of weeks to months, we analyzed the initial 24–48 h of snow evolution at a high temporal resolution of 3 hours. The data set comprised natural and laboratory-grown snow, and experimental conditions included systematic variations of overburden stress, temperature and crystal habit to address the main influences on specific surface area (SSA decrease rate and densification rate in a snowpack. For all conditions, we found a linear relation between density and SSA, indicating that metamorphism has an immediate influence for the densification of new snow. The slope of the linear relation, however, depends on the other parameters which were analyzed individually to derive a best-fit parameterization for the SSA decrease rate and densification rate. In the investigated parameter range, we found that the initial value of the SSA constituted the main morphological influence on the SSA decrease rate. In turn, the SSA decrease rate constituted the main influence on the densification rate.

  9. Formation of nickel-doped magnetite hollow nanospheres with high specific surface area and superior removal capability for organic molecules

    Science.gov (United States)

    Li, Zhenhu; Ma, Yurong; Qi, Limin

    2016-12-01

    A strategy for the formation of magnetic Ni x Fe3-x O4 hollow nanospheres with very high specific surface areas was designed through a facile solvothermal method in mixed solvents of ethylene glycol and water in this work. The Ni/Fe ratios and the crystal phases of the Ni x Fe3-x O4 hollow nanocrystals can be readily tuned by changing the molar ratios of Ni to Fe in the precursors. An inside-out Ostwald ripening mechanism was proposed for the formation of uniform Ni x Fe3-x O4 hollow nanospheres. Moreover, the obtained Ni x Fe3-x O4 hollow nanospheres exhibited excellent adsorption capacity towards organic molecules such as Congo red in water. The maximum adsorption capacities of Ni x Fe3-x O4 hollow nanospheres for Congo red increase dramatically from 263 to 500 mg g-1 with the increase of the Ni contents (x) in Ni x Fe3-x O4 hollow nanospheres from 0.2 to 0.85. The synthesized Ni x Fe3-x O4 nanoparticles can be potentially applied for waste water treatment.

  10. THE EFFECT OF STORAGE AT AMBIENT HUMIDITY ON THE BET-SPECIFIC SURFACE-AREA OF TABLETS COMPACTED FROM DIFFERENT MATERIALS

    NARCIS (Netherlands)

    RIEPMA, KA; DEKKER, BG; JAGER, RS; ELBERSE, PA; LERK, CF

    1993-01-01

    Tablets compacted from both water soluble and water insoluble particulate solids showed no change in BET-specific surface area when transferred immediately after ejection from the die in a dry atmosphere. Storage at ambient humidity resulted in an irreversible decrease in surface area, caused by cap

  11. Application specific Tester-On-a-Resident-Chip (TORCH{trademark}) - innovation in the area of semiconductor testing

    Energy Technology Data Exchange (ETDEWEB)

    Bowles, M. [L& M Technologies, Albuquerque, NM (United States); Peterson, T. [New Mexico Highlands Univ., Las Vegas, NM (United States); Savignon, D.; Campbell, D. [Sandia National Labs., Albuquerque, NM (United States)

    1997-12-01

    Manufacturers widely recognize testing as a major factor in the cost, producability, and delivery of product in the $100 billion integrated circuit business: {open_quotes}The rapid development of VLSI using sub-micron CMOS technology has suddenly exposed traditional test techniques as a major cost factor that could restrict the development of VLSI devices exceeding 512 pins an operating frequencies above 200 MHz.{close_quotes} -- 1994 Semiconductor Industry Association Roadmap, Design and Test, Summary, pg. 43. This problem increases dramatically for stockpile electronics, where small production quantities make it difficult to amortize the cost of increasingly expensive testers. Application of multiple ICs in Multi-Chip Modules (MCM) greatly multiplies testing problems for commercial and defense users alike. By traditional test methods, each new design requires custom test hardware and software and often dedicated testing equipment costing millions of dollars. Also, physical properties of traditional test systems often dedicated testing equipment costing millions of dollars. Also, physical properties of traditional test systems limit capabilities in testing at-speed (>200 MHz), high-impedance, and high-accuracy analog signals. This project proposed a revolutionary approach to these problems: replace the multi-million dollar external test system with an inexpensive test system integrated onto the product wafer. Such a methodology enables testing functions otherwise unachievable by conventional means, particularly in the areas of high-frequency, at-speed testing, high impedance analog circuits, and known good die assessment. The techniques apply specifically to low volume applications, typical of Defense Programs, where testing costs represent an unusually high proportional of product costs, not easily amortized.

  12. Preparation of activated carbon with low ash content and high specific surface area from coal in the presence of KOH

    Institute of Scientific and Technical Information of China (English)

    XIE Qiang(解强); CHEN Qing-ru(陈清如); GONG Guo-zhuo(宫国卓); ZHANG Xiang-lan(张香兰); XU De-ping(许德平)

    2003-01-01

    An activated carbon with ash content less than 10% and specific surface area more than 1 600 m2/g was prepared from coal and the effect of K-containing compounds in preparation of coal-based activated carbon was investigated in detail in this paper. KOH was used in co-carbonization with coal, changes in graphitic crystallites in chars derived from carbonization of coal with and without KOH were analyzed by X-ray diffraction (XRD) technique, activation rates of chars with different contents of K-containing compounds were deduced, and resulting activated carbons were characterized by nitrogen adsorption isotherms at 77 K and iodine numbers. The results showed that the addition of KOH to the coal before carbonization can realize the intensive removal of inorganic matters from chars under mild conditions, especially the efficient removal of dispersive quartz, an extremely difficult separated mineral component in other processes else. Apart from this, KOH demonstrates a favorable effect in control over coal carbonization with the goal to form nongraphitizable isotropic carbon precursor, which is a necessary prerequisite for the formation and development of micro pores. However, the K-containing compounds such as K2CO3 and K2O remaining in chars after carbonization catalyze the reaction between carbon and steam in activation, which leads to the formation of macro pores. In the end an innovative method, in which KOH is added to coal before carbonization and K-containing compounds are removed by acid washing after carbonization, was proposed for the synthesis of quality coal-based activated carbon.

  13. A coupled physical, optical, and photochemical model of snow: relating measurements of specific surface area to snow optical properties.

    Science.gov (United States)

    Phillips, G.; Simpson, W. R.; Taillandier, A.; Domine, F.

    2004-12-01

    Recent experiments and modeling studies have shown that chemical processes in the snow pack have significant impacts on the chemistry of the atmosphere. Solar ultraviolet radiation penetrating the snow pack is the driving force for some of these chemical processes. Therefore, factors controlling photochemical processes in the snowpack need to be understood. Here, we present field investigations of the relationship between physical and optical properties of the snowpack and laboratory studies validating radiation models that predict photochemical reaction rates within the snowpack. A critical parameter in modeling snow photochemistry is the scattering coefficient for the snow. Steve Warren (University of Washington) proposed that the best physical measurement that correlates with scattering is the specific surface area (SSA); however, this correlation has not been tested to our knowledge. Therefore, we performed field experiments comparing optical measurements of scattering and the SSA. The measurement of the snow SSA was achieved by using the Brunauer-Emmett-Teller method to analyse CH4 adsorption onto snow samples. The optical determination of scattering in the snowpack used a variation of the method of Beaglehole. In this method, the light penetration of a snow sample was measured using decreasing thicknesses of the sample on a black base. In the thin layers, the scattering dominates the light attenuation within the snow. In the thicker layers both the absorption and scattering determine the light attenuation. Kubelka-Munk two-flux theory was used to model the data and calculate the scattering and absorption within the samples. This determination of the scattering was found to be proportional to the measured SSA. This linkage between SSA and optical properties confirms Warren`s hypothesis and allows the literatures of optical and physical properties of snow to be coupled. A laboratory study of the performance of snow radiation models was also carried out. A delta

  14. Observation and modeling of the seasonal evolution of the snow specific surface area at Dome C in Antarctica

    Science.gov (United States)

    Picard, G.; Libois, Q.; Arnaud, L.; Dumont, M.; Lafaysse, M.; Morin, S.

    2015-12-01

    The specific surface area (SSA) of surface snow evolves in response to meteorological conditions (e.g. temperature and precipitation). It is the main driver of the albedo in the near infrared range where most of the solar energy is absorbed in Antarctica. In turn, albedo change affects snow temperature, which drives SSA evolution rate, and at a larger scale influences the climate of snow-covered regions through snow-albedo feedback loops. Here we present a SSA retrieval method based on in-situ spectral albedo measurements and explore the factors limiting the accuracy of this method. The snowpack model Crocus is also used to simulate SSA evolution, and to investigate the respective role of temperature and precipitation Automatic spectral measurements of the upwelling and downwelling irradiance in the range 800nm - 1050nm are acquired every hour with a spectrophotometer deployed at Dome C since 2012. Spectral albedo is derived from these measurements and is used in conjunction with an asymptotic analytical solution of the radiative transfer equation to retrieve surface SSA estimates representative of the topmost centimeter. The sensitivity analysis of this method shows that the spectro-angular response of the cosine collector used to capture the light, and the uncertainty in the surface roughness are the largest sources of error, and can account for up to 20% uncertainty in SSA retrieval. In contrast, the dark current of the spectrometer, the inter-calibration of the upwelling and downwelling lines are good enough or sufficiently easy to correct not to impact the retrieval. To compare the surface SSA time-series to Crocus simulations, a few adaptations to the Antarctic conditions have been implemented in the model. The results show that the Crocus successfully matches the observations at daily to seasonal time scales, except for a few cases when snowfalls are not present in the meteorological forcing. On the contrary, the inter-annual variability of summer SSA

  15. Zellweger Spectrum

    Science.gov (United States)

    ... severe defect, resulting in essentially nonfunctional peroxisomes. This phenomenon produces the range of severity of the disorders. How is the Zellweger Spectrum Diagnosed? The distinctive shape of the head and face of a child born with one of the diseases of the ...

  16. Male-specific alteration in excitatory post-synaptic development and social interaction in pre-natal valproic acid exposure model of autism spectrum disorder.

    Science.gov (United States)

    Kim, Ki Chan; Kim, Pitna; Go, Hyo Sang; Choi, Chang Soon; Park, Jin Hee; Kim, Hee Jin; Jeon, Se Jin; Dela Pena, Ike Campomayor; Han, Seol-Heui; Cheong, Jae Hoon; Ryu, Jong Hoon; Shin, Chan Young

    2013-03-01

    Autism spectrum disorder (ASD) is a pervasive developmental disorder characterized by three main behavioral symptoms including social deficits, impaired communication, and stereotyped and repetitive behaviors. ASD prevalence shows gender bias to male. Prenatal exposure to valproic acid (VPA), a drug used in epilepsy and bipolar disorder, induces autistic symptoms in both human and rodents. As we reported previously, prenatally VPA-exposed animals at E12 showed impairment in social behavior without any overt reproductive toxicity. Social interactions were not significantly different between male and female rats in control condition. However, VPA-exposed male offspring showed significantly impaired social interaction while female offspring showed only marginal deficits in social interaction. Similar male inclination was observed in hyperactivity behavior induced by VPA. In addition to the ASD-like behavioral phenotype, prenatally VPA-exposed rat offspring shows crooked tail phenotype, which was not different between male and female groups. Both male and female rat showed reduced GABAergic neuronal marker GAD and increased glutamatergic neuronal marker vGluT1 expression. Interestingly, despite of the similar increased expression of vGluT1, post-synaptic marker proteins such as PSD-95 and α-CAMKII expression was significantly elevated only in male offspring. Electron microscopy showed increased number of post-synapse in male but not in female at 4 weeks of age. These results might suggest that the altered glutamatergic neuronal differentiation leads to deranged post-synaptic maturation only in male offspring prenatally exposed to VPA. Consistent with the increased post-synaptic compartment, VPA-exposed male rats showed higher sensitivity to electric shock than VPA-exposed female rats. These results suggest that prenatally VPA-exposed rats show the male preponderance of ASD-like behaviors including defective social interaction similar to human autistic patients, which

  17. Influence of excess sodium ions on the specific surface area formation in a NiO-Al2O3 catalyst prepared by different methods

    Directory of Open Access Journals (Sweden)

    Lazić M.M.

    2008-01-01

    Full Text Available The influence of sodium ions on the specific surface area of a NiO-Al2O3 catalyst in dependence of nickel loading (5, 10, and 20 wt% Ni, temperature of heat treatment (400, 700 and 1100oC and the method of sample preparation was investigated. Low temperature nitrogen adsorption (LTNA, X-ray diffraction (XRD and scanning electron microscopy (SEM were applied for sample characterization. Dramatic differences in the specific surface area were registered between non-rinsed and rinsed Al2O3 and NiO-Al2O3 samples. The lagged sodium ions promote sintering of non-rinsed catalyst samples.

  18. An abbreviated MLVA identifies Escherichia coli ST131 as the major extended-spectrum β-lactamase-producing lineage in the Copenhagen area

    DEFF Research Database (Denmark)

    Nielsen, J. B.; Albayati, A.; Jørgensen, R. L.;

    2013-01-01

    Rapid bacterial typing is a valuable and necessary tool in the prevention and detection of outbreaks. The purpose of this study was to adapt a multilocus variable number of tandem repeats analysis (MLVA) for analysis on a benchtop capillary electrophoresis instrument and compare the modified assay...... with multilocus sequence typing (MLST) for typing cefpodoxime-resistant Escherichia coli (E. coli). Further, we identified the causative resistance mechanisms and epidemiological type of infection for isolates producing extended-spectrum β-lactamases (ESBLs). A collection of E. coli resistant to cefpodoxime...... was typed by MLST and a modified MLVA assay using a benchtop capillary electrophoresis instrument. Resistance mechanisms were identified by polymerase chain reaction (PCR) and sequencing. Patient history was examined to establish the epidemiological type of infection for ESBL-producing E. coli. MLVA yielded...

  19. Specific solvent effects of linear alcohols on the emission spectrum and the excited state decay of tris(2,2'-bipyridyl) ruthenium(I)

    Science.gov (United States)

    Hartmann, Paul; Leiner, Marc J. P.; Draxler, Sonja; Lippitsch, Max E.

    1996-06-01

    This study aims at a quantitative extraction of specific solvent effects of hydroxylic solvents on the non-radiative decay of tris(2,2'-bipyridyl) ruthenium(II). For this purpose the emission spectra, quantum yields and excited state lifetimes of the dye were measured in a series of monovalent linear alcohols. Separation of the non-radiative decay via the energy gap was achieved by evaluating the temperature dependence of quantum yields to account for temperature-activated transitions. The parameters determining the shapes of the emission spectra were calculated by a modified Franck-Condon analysis including the anharmonic Morse potential, and correlated with the non-radiative rate with the help of the energy gap law. The specific effects of hydroxylic solvents were finally obtained by comparison with the well-known behavior in non-hydroxylic solvents, and interpreted with the help of the energy gap law theory.

  20. Accurate tissue area measurements with considerably reduced radiation dose achieved by patient-specific CT scan parameters

    DEFF Research Database (Denmark)

    Brandberg, J.; Bergelin, E.; Sjostrom, L.;

    2008-01-01

    to cover a wide range of diameters (31-47 cm) for both abdomen and thighs - were examined using both techniques. Tissue areas were compared, as were CT numbers...... for muscle tissue. Image noise was quantified by standard deviation measurements. The area deviation was ... as compared with the integral dose by the standard diagnostic technique. The CT numbers of muscle tissue remained unchanged with reduced radiation dose. Image noise was on average 20.9 HU (Hounsfield units) for subjects with diameters of 31-35 cm and 11.2 HU for subjects with diameters in the range of 36...

  1. Ultradrawing and Ultimate Tenacity Properties of Ultrahigh Molecular Weight Polyethylene Composite Fibers Filled with Nanosilica Particles with Varying Specific Surface Areas

    Directory of Open Access Journals (Sweden)

    Jen-taut Yeh

    2015-01-01

    Full Text Available Original and/or functionalized nanosilica particles with a quoted specific surface area of 100, 300, and 600 m2/g, respectively, were used to investigate the influence of specific surface areas of nanosilica particles on ultradrawing and ultimate tensile properties of ultrahigh molecular weight polyethylene (UHMWPE, UHMWPE/nanosilica, and UHMWPE/functionalized nanosilica fibers. The specific surface areas of well-dispersed functionalized nanosilica particles in UHMWPE/functionalized nanosilica fibers can positively affect their ultradrawing, orientation, ultimate tensile properties, and “micro-fibrils” morphologies. Excellent orientation and ultimate tensile properties of UHMWPE/nanofiller fibers can be prepared by ultradrawing the UHMWPE/functionalized nanosilica as-prepared fibers with optimal contents of the best prepared functionalized nanosilica particles well dispersing in the as-prepared fibers. The ultimate tensile strength value of the best prepared UHMWPE/functionalized nanosilica drawn fiber reaches 7.6 GPa, which is about 2.3 times of those of the best prepared UHMWPE drawn fiber without addition of any nanofiller. Specific surface area, morphological and Fourier transform infrared analyses of original and functionalized nanosilica particles, and/or investigations of thermal, orientation factor, and ultimate tensile properties of as-prepared and/or drawn UHMWPE/functionalized nanosilica fibers were performed to understand the above improved ultradrawing and ultimate tensile properties of the UHMWPE/functionalized nanosilica as-prepared and/or drawn fibers.

  2. Reduction on NOx emissions on urban areas by changing specific vehicle fleets: effects on NO2 and O3 concentration

    Science.gov (United States)

    Goncalves, M.; Jimenez, P.; Baldasano, J.

    2007-12-01

    The largest amount of NOx emissions in urban areas comes from on-road traffic, which is the largest contributor to urban air pollution (Colvile et al., 2001). Currently different strategies are being tested in order to reduce its effects; many of them oriented to the reduction of the unitary vehicles emissions, by alternative fuels use (such as biofuels, natural gas or hydrogen) or introduction of new technologies (such as hybrid electric vehicles or fuel cells). Atmospheric modelling permits to predict their consequences on tropospheric chemistry (Vautard et al., 2007). Hence, this work assesses the changes on NO2 and O3 concentrations when substituting a 10 per cent of the urban private cars fleets by petrol hybrid electric cars (HEC) or by natural gas cars (NGC) in Madrid and Barcelona urban areas (Spain). These two cities are selected in order to highlight the different patterns of pollutants transport (inland vs. coastal city) and the different responses to emissions reductions. The results focus on a typical summertime episode of air pollution, by means of the Eulerian air quality model ARW- WRF/HERMES/CMAQ, applied with high resolution (1-hr, 1km2) since of the complexity of both areas under study. The detailed emissions scenarios are implemented in the HERMES traffic emissions module, based on the Copert III-EEA/EMEP-CORINAIR (Nztiachristos and Samaras, 2000) methodology. The HEC introduction reduces NOx emissions from on-road traffic in a 10.8 per cent and 8.2 per cent; and the NGC introduction in a 10.3 per cent and 7.8 per cent, for Madrid and Barcelona areas, respectively. The scenarios also affect the NMVOCs reduction (ranging from -3.1 to -6.9 per cent), influencing the tropospheric photochemistry through the NOx/NMVOCs ratio. The abatement of the NO photooxidation but also to the reduction on primary NO2 involves a decrease on NO2 levels centred on urban areas. For example, the NO2 24-hr average concentration in downtown areas reduces up to 8 per

  3. [Specific Features of Radioactive Pollution of Soils of Catchment Areas of Lake Shablish (Distant Zone of the East Ural Radioactive Trace)].

    Science.gov (United States)

    Deryagin, V V; Levina, S G; Sutyagin, A A; Parfilova, N S

    2015-01-01

    Specific features of 90Sr and 137Cs distribution and accumulation in soil cuts of superaqueous and eluvial positions of catchment areas of Lake Shablish located in a distant zone of the East Ural radioactive trace are considered. Some physical and chemical characteristics of the soils were defined. It is established that the signs typical for the lake ecosystems of distant East-Ural radioactive trace zone which underwent impact of technogenic influence are common for soils of catchment areas of Lake Shablish. The distinctions in some characteristic features of the specific activity of long-living radionuclides for the soils of superaqueous and eluvial positions of catchment areas connected with the character of the water regime of soils are shown.

  4. Online Speaking Strategy Assessment for Improving Speaking Ability in the Area of Language for Specific Purposes: The Case of Tourism

    Science.gov (United States)

    Phaiboonnugulkij, Malinee; Prapphal, Kanchana

    2013-01-01

    The purpose of this study was to compare the differences in strategies used in an online language for specific purposes (LSP) speaking test in tourism with two proficiency groups of students, and to investigate the strategies that should be used for low-proficiency students to improve their LSP speaking ability. The Web-based Speaking Test in…

  5. Conformation-specific spectroscopy of alkyl benzyl radicals: Effects of a radical center on the CH stretch infrared spectrum of an alkyl chain

    Science.gov (United States)

    Korn, Joseph A.; Tabor, Daniel P.; Sibert, Edwin L.; Zwier, Timothy S.

    2016-09-01

    An important initial step in the combustion of gasoline and diesel fuels is the abstraction of hydrogen from alkylbenzenes to form resonance-stabilized alkyl benzyl radicals. This work uses, for the first time, double resonance spectroscopy methods to explore the conformation-specific vibronic and infrared spectroscopy of the α-ethylbenzyl (αEtBz) and α-propylbenzyl (αPrBz) radicals. Local mode Hamiltonian modeling enables assignment of the alkyl CH stretch IR spectra, accounting for Fermi resonance that complicates aliphatic alkyl CH stretch IR spectroscopy. The ground state conformational preferences of the ethyl and propyl chains are changed from those in the alkylbenzenes themselves, with global minima occurring for an in-plane orientation of the alkyl chain (trans) about its first dihedral angle (ϕf123, numbers are alkyl C atoms. C1 is CH radical site). This in-plane structure is the only observed conformer for the α-EtBz radical, while two conformers, tt and tg' share this orientation at the first dihedral, but differ in the second (ϕ1234) for the αPrBz radical. The in-plane orientation lowers the local site frequencies of the CH2 group stretches immediately adjacent to the benzylic radical site by about 50 cm-1 relative to those in pure alkyl chains or alkylbenzenes. This effect of the radical site is localized on the first CH2 group, with little effect on subsequent members of the alkyl chain. In the D1 excited electronic state, an out-of-plane orientation is preferred for the alkyl chains, leading to torsional mode Franck-Condon activity in the D0-D1 spectra that is both conformer-specific and diagnostic of the conformational change.

  6. Probability-consistent spectrum and code spectrum

    Institute of Scientific and Technical Information of China (English)

    沈建文; 石树中

    2004-01-01

    In the seismic safety evaluation (SSE) for key projects, the probability-consistent spectrum (PCS), usually obtained from probabilistic seismic hazard analysis (PSHA), is not consistent with the design response spectrum given by Code for Seismic Design of Buildings (GB50011-2001). Sometimes, there may be a remarkable difference between them. If the PCS is lower than the corresponding code design response spectrum (CDS), the seismic fortification criterion for the key projects would be lower than that for the general industry and civil buildings. In the paper, the relation between PCS and CDS is discussed by using the ideal simple potential seismic source. The results show that in the most areas influenced mainly by the potential sources of the epicentral earthquakes and the regional earthquakes, PCS is generally lower than CDS in the long periods. We point out that the long-period response spectra of the code should be further studied and combined with the probability method of seismic zoning as much as possible. Because of the uncertainties in SSE, it should be prudent to use the long-period response spectra given by SSE for key projects when they are lower than CDS.

  7. Effect of Surfactant/Silica and Hydrothermal Time on the Specific Surface Area of Mesoporous Materials from Coal-Measure Kaolin

    Institute of Scientific and Technical Information of China (English)

    WU Qisheng; LI Shuiping

    2011-01-01

    Mesoporous materials with the highest surface area were synthesized by hydrothermal treatment from coal-measure kaolin using cetyltrimethylammonium bromide (CTAB) as template. The effect of several factors on surface area of products also had been discussed. The products were characterized by FTIR, HRTEM and N2 adsorption and desorption isotherm plot methods. There was typical structure as Si-O, Si-OH and Si-O-Si of mesoporous materials in the framework of synthesized materials; the pore size distributions of the products showed a sharp peak at 3.82 nm. The effect of hydrothermal treatment time and the amount of template on the specific surface area of mesoporous materials was important, when the Surf/Si = 0.135, and hydrothermal time = 12 h, and the surface area of the product reached up to 1 070 m2/g, which was higher than other products.

  8. Fission Spectrum

    Science.gov (United States)

    Bloch, F.; Staub, H.

    1943-08-18

    Measurements of the spectrum of the fission neutrons of 25 are described, in which the energy of the neutrons is determined from the ionization produced by individual hydrogen recoils. The slow neutrons producing fission are obtained by slowing down the fast neutrons from the Be-D reaction of the Stanford cyclotron. In order to distinguish between fission neutrons and the remaining fast cyclotron neutrons both the cyclotron current and the pusle amplifier are modulated. A hollow neutron container, in which slow neutrons have a lifetime of about 2 milliseconds, avoids the use of large distances. This method results in much higher intensities than the usual modulation arrangement. The results show a continuous distribution of neutrons with a rather wide maximum at about 0.8 MV falling off to half of its maximum value at 2.0 MV. The total number of netrons is determined by comparison with the number of fission fragments. The result seems to indicate that only about 30% of the neutrons have energies below .8 MV. Various tests are described which were performed in order to rule out modification of the spectrum by inelastic scattering. Decl. May 4, 1951

  9. Are Sport-Specific Profiles of Tendon Stiffness and Cross-Sectional Area Determined by Structural or Functional Integrity?

    Directory of Open Access Journals (Sweden)

    Hans-Peter Wiesinger

    Full Text Available The present study aimed to determine whether distinct sets of tendon properties are seen in athletes engaged in sports with contrasting requirements for tendon function and structural integrity. Patellar and Achilles tendon morphology and force-deformation relation were measured by combining ultrasonography, electromyography and dynamometry in elite ski jumpers, distance runners, water polo players and sedentary individuals. Tendon cross-sectional area normalized to body mass2/3 was smaller in water polo players than in other athletes (patellar and Achilles tendon; -28 to -24% or controls (patellar tendon only; -9%. In contrast, the normalized cross-sectional area was larger in runners (patellar tendon only; +26% and ski jumpers (patellar and Achilles tendon; +21% and +13%, respectively than in controls. Tendon stiffness normalized to body mass2/3 only differed in ski jumpers, compared to controls (patellar and Achilles tendon; +11% and +27%, respectively and to water polo players (Achilles tendon only; +23%. Tendon size appears as an adjusting variable to changes in loading volume and/or intensity, possibly to preserve ultimate strength or fatigue resistance. However, uncoupled morphological and mechanical properties indicate that functional requirements may also influence tendon adaptations.

  10. Inverse gas chromatography for natural fibre characterisation: Identification of the critical parameters to determine the Brunauer-Emmett-Teller specific surface area.

    Science.gov (United States)

    Legras, A; Kondor, A; Heitzmann, M T; Truss, R W

    2015-12-18

    Inverse gas chromatography (IGC) is an alternative technique to determine the specific surface area of natural fibres. Natural fibres have a complex surface chemistry and unique microstructure that challenge the current capabilities to perform surface characterisation. This study investigated the influence of multiple parameters on the measured Brunauer-Emmett-Teller (BET) specific surface area for samples of flax, kenaf and BioMid(®) cellulose fibres using IGC. The BET surface area of kenaf and flax differed with 0.51m(2)g(-1) and 1.35m(2)g(-1) respectively, the former being similar to the cellulose fibres (0.54m(2)g(-1)). The data was calculated under conditions where the BET equation showed good linearity (R(2)⩾0.995). Repeatability was excellent so that two runs sufficed to obtain representative BET surface area values. The findings showed the choice of solvent was important for all specimens to avoid any misleading data comparison due to molecular orientation effects that impact the adsorbent-adsorbate interactions. The higher surface area of the flax sample, and its higher variability, was correlated with a higher surface roughness observed under optical microscopy. Packing the chromatography column with long or chopped fibres produced results that were statistically insignificant.

  11. Synthesis of murdochite-type Ni{sub 6}MnO{sub 8} with variable specific surface areas and the application in methane oxidation

    Energy Technology Data Exchange (ETDEWEB)

    Taguchi, Hideki, E-mail: htaguchi@cc.okayama-u.ac.jp [The Graduate School of Natural Science and Technology (Science), Okayama University, 3-1-1 Tsushima-Naka, Kita-Ku, Okayama 700-8530 (Japan); Tahara, Shohei [The Graduate School of Natural Science and Technology (Science), Okayama University, 3-1-1 Tsushima-Naka, Kita-Ku, Okayama 700-8530 (Japan); Okumura, Mikoto; Hirota, Ken [Department of Molecular Chemistry and Biochemistry, Faculty of Science and Engineering, Doshisha University, Kyo-Tanabe 610-0321 (Japan)

    2014-07-01

    To synthesize a murdochite-type Ni{sub 6}MnO{sub 8} with variable specific surface areas, an oxalate precursor was calcined at 350–500 °C in flowing argon, and the calcined sample was heated to 600 °C in air. The lattice constant of the Ni{sub 6}MnO{sub 8} did not depend on the calcination temperature of the precursor, while the specific surface area decreased from 8.4 m{sup 2}/g to 2.6 m{sup 2}/g when increasing the calcination temperature of the precursor. The methane (CH{sub 4}) oxidation data indicated that the temperature corresponding to the 50% conversion (T{sub 50%}) of Ni{sub 6}MnO{sub 8} calcined at 350 °C or 400 °C was lower than that of all other Ni{sub 6}MnO{sub 8} specimens. However, the intrinsic conversion of Ni{sub 6}MnO{sub 8} calcined at 350 °C, which is defined as conversion per specific surface area, was half of that of all other Ni{sub 6}MnO{sub 8} specimens. The degree of crystallinity and catalytic performance of the Ni{sub 6}MnO{sub 8} calcined at 400 °C were high. - Graphical abstract: The conversion of CH{sub 4} into CO{sub 2} and H{sub 2}O on Ni{sub 6}MnO{sub 8}, which was heated at 600 °C in air after the calcination of the precursor at 350 °C, 400 °C, 450 °C, or 500 °C in flowing argon, was measured. Since the specific surface area was strongly affected by the calcination temperature of the precursor, intrinsic conversion (IC) was defined as conversion per the specific surface area. For comparison, the IC value on Ni{sub 6}MnO{sub 8} synthesized by the direct calcination of the precursor at 600 °C in air is plotted. - Highlights: • The oxalate precursor was calcined at 350–500 °C in flowing argon. • Murdochite-type Ni{sub 6}MnO{sub 8} was obtained by heating the calcined sample in air. • The specific surface area of Ni{sub 6}MnO{sub 8} varied with the calcination temperature. • The degree of crystallinity and catalysis of Ni{sub 6}MnO{sub 8} calcined at 400 °C were high.

  12. Relationship between specific surface area and the dry end of the water retention curve for soils with varying clay and organic carbon contents

    DEFF Research Database (Denmark)

    Resurreccion, Augustus C.; Møldrup, Per; Tuller, Markus;

    2011-01-01

    with ethylene glycol monoethyl ether (SA_EGME) only for organic soils with n > 10. A strong correlation between the ratio of the two surface area estimates and the Dexter number was observed and applied as an additional scaling function in the TO model to rescale the soil water retention curve at low water...... dominate over capillary forces, have also been used to estimate soil specific surface area (SA). In the present study, the dry end of the SWRC was measured with a chilled-mirror dew point psychrometer for 41 Danish soils covering a wide range of clay (CL) and organic carbon (OC) contents. The 41 soils were...

  13. Prevalence, correlates, and comorbidities of four DSM-IV specific phobia subtypes: results from the Korean Epidemiological Catchment Area study.

    Science.gov (United States)

    Park, Subin; Sohn, Jee Hoon; Hong, Jin Pyo; Chang, Sung Man; Lee, Young Moon; Jeon, Hong Jin; Cho, Seong-Jin; Bae, Jae Nam; Lee, Jun Young; Son, Jung-Woo; Cho, Maeng Je

    2013-10-30

    Although several studies have detected differences in clinical features among specific phobias, there is a shortage of detailed national data on the on the DSM-IV SP subtypes, particularly in the Asian population. To examine the prevalence, demographic and other correlates, and co-morbidities of DSM-IV SP subtypes in a nationwide sample of Korean adults. We recruited 6510 participants aged 18-64 years for this study. Lay interviewers used the Composite International Diagnostic Interview to assess participants. We analyzed socio-demographics, health-related correlates and frequencies of comorbid mental disorders among participants with SP and each subtypes compared to unaffected adults. The prevalence of lifetime DSM-IV SP was 3.8%, and animal phobias were the most prevalent type of SP. Blood-injection-injury phobia was negatively associated with education, whereas situational phobia was positively associated with education. The strongest mental disorder comorbidity was associated with situational phobia; there is a higher probability of comorbid mood (OR=5.73, 95% CI=2.09-15.73), anxiety (OR=7.54, 95% CI=2.34-24.28), and somatoform disorders (OR=7.61, 95% CI=1.64-35.22) with this subtype. Blood-injection-injury phobia was highly associated with alcohol dependence (OR=9.02, 95% CI=3.54-23.02). Specific phobias are heterogeneous with respect to socio-demographic characteristics and comorbidity pattern. Implications of the usefulness of current subtype categories should continue to be investigated.

  14. The definition analyses of radiation temperature measurement area

    Institute of Scientific and Technical Information of China (English)

    Fu Tairan; Cheng Xiaofang; Zhong Maohua

    2008-01-01

    In the research of primary spectrum pyrometry, this paper discussed the definition problem of radiation tem-perature measurement area based on the measurement coordinates. For the linear spectrum emissivity model and im-proved monotonic spectrum emissivity model, the characteristics of radiation temperature measurement area restricted by the measurement coordinates were theoretically analyzed, through the investigations of the temperature and emissivity co-ordinate axes. Choosing the specific primary spectrum pyrometer as an example in applications, the theoretical area of radiation temperature measurement of this pyrometer was given and it was verified through blackbody experiments. The discussions of this paper will provide the necessary foundation for the theory research development of primary spectrum pyrometry and the realization of technical applications.

  15. Spatial Organization of the Cytoskeleton enhances Cargo Delivery to Specific Target Areas on the Plasma Membrane of Spherical Cells

    CERN Document Server

    Hafner, Anne E

    2016-01-01

    Intracellular transport is vital for the proper functioning and survival of a cell. Cargo (proteins, vesicles, organelles, etc.) is transferred from its place of creation to its target locations via molecular motor assisted transport along cytoskeletal filaments. The transport efficiency is strongly affected by the spatial organization of the cytoskeleton, which constitutes an inhomogeneous, complex network. In cells with a centrosome microtubules grow radially from the central microtubule organizing center towards the cell periphery whereas actin filaments form a dense meshwork, the actin cortex, underneath the cell membrane with a broad range of orientations. The emerging ballistic motion along filaments is frequently interrupted due to constricting intersection nodes or cycles of detachment and reattachment processes in the crowded cytoplasm. In order to investigate the efficiency of search strategies established by the cell's specific spatial organization of the cytoskeleton we formulate a random velocity...

  16. Specific interface area and self-stirring in a two-liquid system experiencing intense interfacial boiling below the bulk boiling temperatures of both components

    CERN Document Server

    Goldobin, Denis S

    2016-01-01

    We present an approach to theoretical assessment of the mean specific interface area $(\\delta{S}/\\delta{V})$ for a well-stirred system of two immiscible liquids experiencing interfacial boiling. The assessment is based on the balance of transformations of mechanical energy and the laws of the momentum and heat transfer in the turbulent boundary layer. The theory yields relations between the specific interface area and the characteristics of the system state. In particular, this allows us to derive the equations of self-cooling dynamics of the system in the absence of external heat supply. The results provide possibility for constructing a self-contained mathematical description of the process of interfacial boiling. In this study, we assume the volume fractions of two components to be similar as well as the values of their kinematic viscosity and molecular heat diffusivity.

  17. Fabrication and characterization of Ce0.7Zr0.3O2 nanorods having high specific surface area and large oxygen storage capacity

    Institute of Scientific and Technical Information of China (English)

    Yucheng Du; Shuli Shi; Hong He; Hongxing Dai

    2011-01-01

    Nanorod-like Ce0.7Zr0.3O2 solid solutions were synthesized by a sodium dodecyl sulfate-assisted precipitation method. The samples were characterized by means of scanning electron microscopy,transmission electron microscopy,X-ray diffraction,Fourier transform infrared spectroscopy,and specific surface area measurement. Typical Ce0.7Zr0.3O2 nanorods were 40 nm in average diameter and 450 nm in length,with specific surface area and oxygen storage capacity of 194 m2/g and 374 μmol/g,respectively.(c) 2010 Chinese Society of Particuology and Institute of Process Engineering,Chinese Academy of Sciences. Published by Elsevier B.V. All rights reserved.

  18. Modulation of Specific Sensory Cortical Areas by Segregated Basal Forebrain Cholinergic Neurons Demonstrated by Neuronal Tracing and Optogenetic Stimulation in Mice

    Science.gov (United States)

    Chaves-Coira, Irene; Barros-Zulaica, Natali; Rodrigo-Angulo, Margarita; Núñez, Ángel

    2016-01-01

    Neocortical cholinergic activity plays a fundamental role in sensory processing and cognitive functions. Previous results have suggested a refined anatomical and functional topographical organization of basal forebrain (BF) projections that may control cortical sensory processing in a specific manner. We have used retrograde anatomical procedures to demonstrate the existence of specific neuronal groups in the BF involved in the control of specific sensory cortices. Fluoro-Gold (FlGo) and Fast Blue (FB) fluorescent retrograde tracers were deposited into the primary somatosensory (S1) and primary auditory (A1) cortices in mice. Our results revealed that the BF is a heterogeneous area in which neurons projecting to different cortical areas are segregated into different neuronal groups. Most of the neurons located in the horizontal limb of the diagonal band of Broca (HDB) projected to the S1 cortex, indicating that this area is specialized in the sensory processing of tactile stimuli. However, the nucleus basalis magnocellularis (B) nucleus shows a similar number of cells projecting to the S1 as to the A1 cortices. In addition, we analyzed the cholinergic effects on the S1 and A1 cortical sensory responses by optogenetic stimulation of the BF neurons in urethane-anesthetized transgenic mice. We used transgenic mice expressing the light-activated cation channel, channelrhodopsin-2, tagged with a fluorescent protein (ChR2-YFP) under the control of the choline-acetyl transferase promoter (ChAT). Cortical evoked potentials were induced by whisker deflections or by auditory clicks. According to the anatomical results, optogenetic HDB stimulation induced more extensive facilitation of tactile evoked potentials in S1 than auditory evoked potentials in A1, while optogenetic stimulation of the B nucleus facilitated either tactile or auditory evoked potentials equally. Consequently, our results suggest that cholinergic projections to the cortex are organized into segregated

  19. Modulation of specific sensory cortical areas by segregated basal forebrain cholinergic neurons demonstrated by neuronal tracing and optogenetic stimulation in mice

    Directory of Open Access Journals (Sweden)

    Irene eChaves-Coira

    2016-04-01

    Full Text Available Neocortical cholinergic activity plays a fundamental role in sensory processing and cognitive functions. Previous results have suggested a refined anatomical and functional topographical organization of basal forebrain (BF projections that may control cortical sensory processing in a specific manner. We have used retrograde anatomical procedures to demonstrate the existence of specific neuronal groups in the BF involved in the control of specific sensory cortices. Fluoro-gold and Fast Blue fluorescent retrograde tracers were deposited into the primary somatosensory (S1 and primary auditory (A1 cortices in mice. Our results revealed that the BF is a heterogeneous area in which neurons projecting to different cortical areas are segregated into different neuronal groups. Most of the neurons located in the horizontal limb of the diagonal band of Broca (HDB projected to the S1 cortex, indicating that this area is specialized in the sensory processing of tactile stimuli. However, the nucleus basalis magnocellularis (B nucleus shows a similar number of cells projecting to the S1 as to the A1 cortices. In addition, we analyzed the cholinergic effects on the S1 and A1 cortical sensory responses by optogenetic stimulation of the BF neurons in urethane-anesthetized transgenic mice. We used transgenic mice expressing the light-activated cation channel, channelrhodopsin-2, tagged with a fluorescent protein (ChR2-YFP under the control of the choline-acetyl transferase promoter (ChAT. Cortical evoked potentials were induced by whisker deflections or by auditory clicks. According to the anatomical results, optogenetic HDB stimulation induced more extensive facilitation of tactile evoked potentials in S1 than auditory evoked potentials in A1, while optogenetic stimulation of the B nucleus facilitated either tactile or auditory evoked potentials equally. Consequently, our results suggest that cholinergic projections to the cortex are organized into segregated

  20. Generation of uniform large-area very high frequency plasmas by launching two specific standing waves simultaneously

    Science.gov (United States)

    Chen, Hsin-Liang; Tu, Yen-Cheng; Hsieh, Cheng-Chang; Lin, Deng-Lain; Leou, Keh-Chyang

    2014-09-01

    With the characteristics of higher electron density and lower ion bombardment energy, large-area VHF (very high frequency) plasma enhanced chemical vapor deposition has become an essential manufacturing equipment to improve the production throughput and efficiency of thin film silicon solar cell. However, the combination of high frequency and large electrodes leads to the so-called standing wave effect causing a serious problem for the deposition uniformity of silicon thin film. In order to address this issue, a technique based on the idea of simultaneously launching two standing waves that possess similar amplitudes and are out of phase by 90° in time and space is proposed in this study. A linear plasma reactor with discharge length of 54 cm is tested with two different frequencies including 60 and 80 MHz. The experimental results show that the proposed technique could effectively improve the non-uniformity of VHF plasmas from >±60% when only one standing wave is applied to reactor configuration adopted in this study, in which the standing wave effect along the much shorter dimension can be ignored, the proposed technique is applicable to different frequencies without the need to alter the number and arrangement of power feeding points.

  1. Spatial organization of the cytoskeleton enhances cargo delivery to specific target areas on the plasma membrane of spherical cells

    Science.gov (United States)

    Hafner, Anne E.; Rieger, Heiko

    2016-12-01

    Intracellular transport is vital for the proper functioning and survival of a cell. Cargo (proteins, vesicles, organelles, etc) is transferred from its place of creation to its target locations via molecular motor assisted transport along cytoskeletal filaments. The transport efficiency is strongly affected by the spatial organization of the cytoskeleton, which constitutes an inhomogeneous, complex network. In cells with a centrosome microtubules grow radially from the central microtubule organizing center towards the cell periphery whereas actin filaments form a dense meshwork, the actin cortex, underneath the cell membrane with a broad range of orientations. The emerging ballistic motion along filaments is frequently interrupted due to constricting intersection nodes or cycles of detachment and reattachment processes in the crowded cytoplasm. In order to investigate the efficiency of search strategies established by the cell’s specific spatial organization of the cytoskeleton we formulate a random velocity model with intermittent arrest states. With extensive computer simulations we analyze the dependence of the mean first passage times for narrow escape problems on the structural characteristics of the cytoskeleton, the motor properties and the fraction of time spent in each state. We find that an inhomogeneous architecture with a small width of the actin cortex constitutes an efficient intracellular search strategy.

  2. Sex-specific mediation effect of the right fusiform face area volume on the association between variants in repeat length of AVPR1A RS3 and altruistic behavior in healthy adults.

    Science.gov (United States)

    Wang, Junping; Qin, Wen; Liu, Feng; Liu, Bing; Zhou, Yuan; Jiang, Tianzi; Yu, Chunshui

    2016-07-01

    Microsatellite variants in the arginine vasopressin receptor 1A gene (AVPR1A) RS3 have been associated with normal social behaviors variation and autism spectrum disorders (ASDs) in a sex-specific manner. However, neural mechanisms underlying these associations remain largely unknown. We hypothesized that AVPR1A RS3 variants affect altruistic behavior by modulating the gray matter volume (GMV) of specific brain regions in a sex-specific manner. We investigated 278 young healthy adults using the Dictator Game to assess altruistic behavior. All subjects were genotyped and main effect of AVPR1A RS3 repeat polymorphisms and interaction of genotype-by-sex on the GMV were assessed in a voxel-wise manner. We observed that male subjects with relatively short repeats allocated less money to others and exhibited a significantly smaller GMV in the right fusiform face area (FFA) compared with male long homozygotes. In male subjects, the GMV of the right FFA exhibited a significant positive correlation with altruistic behavior. A mixed mediation and moderation analysis further revealed both a significant mediation effect of the GMV of the right FFA on the association between AVPR1A RS3 repeat polymorphisms and allocation sums and a significant moderation effect of sex (only in males) on the mediation effect. Post hoc analysis showed that the GMV of the right FFA was significantly smaller in male subjects carrying allele 426 than in non-426 carriers. These results suggest that the GMV of the right FFA may be a potential mediator whereby the genetic variants in AVPR1A RS3 affect altruistic behavior in healthy male subjects. Hum Brain Mapp 37:2700-2709, 2016. © 2016 Wiley Periodicals, Inc.

  3. Evaluation of brain perfusion in specific Brodmann areas in Frontotemporal dementia and Alzheimer disease using automated 3-D voxel based analysis

    Energy Technology Data Exchange (ETDEWEB)

    Valotassiou, V; Tsougos, I; Tzavara, C; Georgoulias, P [Nuclear Medicine Dpt, University Hospital of Larissa, Larissa (Greece); Papatriantafyllou, J; Karageorgiou, C [Neurology Dpt, General Hospital ' G. Gennimatas' , Athens (Greece); Sifakis, N; Zerva, C [Nuclear Medicine Dpt, ' Alexandra' University Hospital, Athens (Greece)], E-mail: vanvalot@yahoo.gr

    2009-05-15

    Introduction. Brain perfusion studies with single-photon emission computed tomography (SPECT) have been applied in demented patients to provide better discrimination between frontotemporal dementia (FTD) and Alzheimer's disease (AD). Aim. To assess the perfusion of specific Brodmann (Br) areas of the brain cortex in FTD and AD patients, using NeuroGam processing program to provide 3D voxel-by-voxel cerebral SPECT analysis. Material and methods. We studied 34 consecutive patients. We used the established criteria for the diagnosis of dementia and the specific established criteria for the diagnosis of FTD and AD. All the patients had a neuropsychological evaluation with a battery of tests including the mini-mental state examination (MMSE).Twenty-six patients (16 males, 10 females, mean age 68.76{+-}6.51 years, education 11.81{+-}4.25 years, MMSE 16.69{+-}9.89) received the diagnosis of FTD and 8 patients (all females, mean age 71.25{+-}10.48 years, education 10{+-}4.6 years, MMSE 12.5{+-}3.89) the diagnosis of AD. All the patients underwent a brain SPECT. We applied the NeuroGam Software for the evaluation of brain perfusion in specific Br areas in the left (L) and right (R) hemispheres. Results. Statistically significant hypoperfusion in FTD compared to AD patients, was found in the following Br areas: 11L (p<0.0001), 11R, 20L, 20R, 32L, 38L, 38R, 44L (p<0.001), 32R, 36L, 36R, 45L, 45R, 47R (p<0.01), 9L, 21L, 39R, 44R, 46R, 47L (p<0.05). On the contrary, AD patients presented significant (p<0.05) hypoperfusion in 7R and 39R Br areas. Conclusion. NeuroGam processing program of brain perfusion SPECT could result in enhanced accuracy for the differential diagnosis between AD and FTD patients.

  4. Comparable study of the buffeting response of Sutong Bridge based on specification and measured wind power spectrum%基于规范及实测风谱的苏通大桥抖振响应对比研究

    Institute of Scientific and Technical Information of China (English)

    王浩; 李爱群; 焦常科; 谢静

    2011-01-01

    Verifying the structural design is one of the major objectives of Structural Health Monitoring System (SHMS) of bridges. Sutong Bridge ( SB), the longest cable-stayed bridge in the world is taken as an example, and the buffeting analysis results using the bridge design specifications is verified by using the measured wind turbulence power spectral density (PSD) function. The measured wind spectrum obtained from strong winds records of the SB site is fitted by using the nonlinear least-squares method, and the three-dimensional turbulence wind fields of the bridge site are simulated by using the measured and specification spectra, respectively. Then, nonlinear time-domain buffeting response analysis of SB is conducted using ANSYS. Comparison of the analysis results shows that, comparing with the one from using the measured spectrum, the buffeting response of the deck derived from the specification spectrum is variable, but the buffeting response of the main tower is inclined to be more conservative. The overall trends of the two types of buffeting response PSDs are basically similar.%复核结构设计是桥梁结构健康监测系统的主要功能之一。以世界第一大跨斜拉桥——苏通大桥为工程背景,采用实测风谱对大桥设计阶段基于规范谱所进行的抖振分析进行验证。首先采用非线性最小二乘法对桥址区实测强风紊流功率谱密度函数进行拟合,获得实测谱曲线,并分别以该实测拟合谱和规范谱为目标谱分别模拟桥址区三维脉动风场。然后采用上述两种风场,基于ANSYS对苏通大桥进行非线性时域抖振响应分析。两种分析结果的对比表明:与实测谱相比,基于规范谱所得的主梁抖振响应情况不一,但主塔抖振响应均偏于保守;两种抖振响应的PSD曲线整体趋势基本一致。分析结果可为该桥的风致抖振性能评价提供研究信息,同时对其他类型结构的抗风设计具有重要的参考价值。

  5. Integrated plant phenotypic responses to contrasting above- and below-ground resources: key roles of specific leaf area and root mass fraction.

    Science.gov (United States)

    Freschet, Grégoire T; Swart, Elferra M; Cornelissen, Johannes H C

    2015-06-01

    Plants adapt phenotypically to different conditions of light and nutrient supply, supposedly in order to achieve colimitation of these resources. Their key variable of adjustment is the ratio of leaf area to root length, which relies on plant biomass allocation and organ morphology. We recorded phenotypic differences in leaf and root mass fractions (LMF, RMF), specific leaf area (SLA) and specific root length (SRL) of 12 herbaceous species grown in factorial combinations of high/low irradiance and fertilization treatments. Leaf area and root length ratios, and their components, were influenced by nonadditive effects between light and nutrient supply, and differences in the strength of plant responses were partly explained by Ellenberg's species values representing ecological optima. Changes in allocation were critical in plant responses to nutrient availability, as the RMF contribution to changes in root length was 2.5× that of the SRL. Contrastingly, morphological adjustments (SLA rather than LMF) made up the bulk of plant response to light availability. Our results suggest largely predictable differences in responses of species and groups of species to environmental change. Nevertheless, they stress the critical need to account for adjustments in below-ground mass allocation to understand the assembly and responses of communities in changing environments.

  6. Spectrum war

    DEFF Research Database (Denmark)

    Henten, Anders; Tadayoni, Reza; Windekilde, Iwona Maria

    communications sector, including commercial mobile operators and the stake holders representing specific uses like Public Safety and Emergency (PSE), Intelligent Traffic System (ITS), etc in getting access to these resources. The paper gives an analysis of the digital dividend and discusses relevant new...

  7. 泡沫镍的制备工艺条件和比表面积%Preparation Technological Conditions and Specific Surface Area of Nickel Foams

    Institute of Scientific and Technical Information of China (English)

    段翠云; 崔光; 刘培生

    2011-01-01

    Based on the technique of electrodeposition on the organic foam, relationship between several deferent specific producing conditions and the corresponding specific surface area of nickel foam products has been investigated.The result showed that the same surface morphology and specific surface area of the nickel foam could be acquired by direct sintering in NH3 decomposition atmosphere at 850 ℃ or 980 ℃ for 40 min after electrodepositing and by burning in air at 600 ℃ for 4 min before and then reductive sintering, after electrodepositing.%本文以有机泡沫电沉积法为基础,探讨了几种具体工艺条件与所得泡沫镍产品比表面积的关系.结果发现,电镀后直接在850~980℃的氨分解气氛中烧结40 min所得产品,与电镀后先在600℃的空气中烧结4 min再进行还原烧结所得产品,具有相同的表面形态和比表面积.

  8. Pulmonary Immune-Compartment-Specific Interferon Gamma Responses in HIV-Infected Individuals with Active Tuberculosis (TB in an Area of High TB Prevalence

    Directory of Open Access Journals (Sweden)

    S. Buldeo

    2012-01-01

    Full Text Available There is a paucity of data on the pulmonary immune-compartment interferon gamma (IFNγ response to M. tuberculosis, particularly in settings of high tuberculosis (TB prevalence and in HIV-coinfected individuals. This data is necessary to understand the diagnostic potential of commercially available interferon gamma release assays (IGRAs in both the pulmonary immune-compartment and peripheral blood. We used intracellular cytokine staining by flow cytometry to assess the IFNγ response to purified protein derivative (PPD and early secretory antigen 6 (ESAT6 in induced sputa (ISp and blood samples from HIV-infected, smear-negative, TB suspects. We found that individuals with active TB disease produced significantly less IFNγ in response to PPD in their induced sputa samples than individuals with non-active TB (control group. This difference was not reflected in the peripheral blood, even within the CD27− CD4+ memory T lymphocyte population. These findings suggest that progression to active TB disease may be associated with the loss of IFNγ secretion at the site of primary infection. Our findings highlight the importance of studying pulmonary immune-compartment M. tuberculosis specific responses to elucidate IFNγ secretion across the spectrum of TB disease.

  9. Growth of porous anodized alumina on the sputtered aluminum films with 2D–3D morphology for high specific surface area

    Energy Technology Data Exchange (ETDEWEB)

    Liao, M.W.; Chung, C.K., E-mail: ckchung@mail.ncku.edu.tw

    2014-08-01

    The porous anodic aluminum oxide (AAO) with high-aspect-ratio pore channels is widely used as a template for fabricating nanowires or other one-dimensional (1D) nanostructures. The high specific surface area of AAO can also be applied to the super capacitor and the supporting substrate for catalysis. The rough surface could be helpful to enhance specific surface area but it generally results in electrical field concentration even to ruin AAO. In this article, the aluminum (Al) films with the varied 2D–3D morphology on Si substrates were prepared using magnetron sputtering at a power of 50 W–185 W for 1 h at a working pressure of 2.5 × 10⁻¹ Pa. Then, AAO was fabricated from the different Al films by means of one-step hybrid pulse anodizing (HPA) between the positive 40 V and the negative -2 V (1 s:1 s) for 3 min in 0.3 M oxalic acid at a room temperature. The microstructure and morphology of Al films were characterized by X-ray diffraction, scanning electron microscope and atomic force microscope, respectively. Some hillocks formed at the high target power could be attributed to the grain texture growth in the normal orientation of Al(1 1 1). The 3D porous AAO structure which is different from the conventional 2D planar one has been successfully demonstrated using HPA on the film with greatly rough hillock-surface formed at the highest power of 185 W. It offers a potential application of the new 3D AAO to high specific surface area devices.

  10. Growth of porous anodized alumina on the sputtered aluminum films with 2D-3D morphology for high specific surface area

    Science.gov (United States)

    Liao, M. W.; Chung, C. K.

    2014-08-01

    The porous anodic aluminum oxide (AAO) with high-aspect-ratio pore channels is widely used as a template for fabricating nanowires or other one-dimensional (1D) nanostructures. The high specific surface area of AAO can also be applied to the super capacitor and the supporting substrate for catalysis. The rough surface could be helpful to enhance specific surface area but it generally results in electrical field concentration even to ruin AAO. In this article, the aluminum (Al) films with the varied 2D-3D morphology on Si substrates were prepared using magnetron sputtering at a power of 50 W-185 W for 1 h at a working pressure of 2.5 × 10-1 Pa. Then, AAO was fabricated from the different Al films by means of one-step hybrid pulse anodizing (HPA) between the positive 40 V and the negative -2 V (1 s:1 s) for 3 min in 0.3 M oxalic acid at a room temperature. The microstructure and morphology of Al films were characterized by X-ray diffraction, scanning electron microscope and atomic force microscope, respectively. Some hillocks formed at the high target power could be attributed to the grain texture growth in the normal orientation of Al(1 1 1). The 3D porous AAO structure which is different from the conventional 2D planar one has been successfully demonstrated using HPA on the film with greatly rough hillock-surface formed at the highest power of 185 W. It offers a potential application of the new 3D AAO to high specific surface area devices.

  11. Specific Surface versus Electrochemically Active Area of the Carbon/Polypyrrole Capacitor: Correlation of Ion Dynamics Studied by an Electrochemical Quartz Crystal Microbalance with BET Surface.

    Science.gov (United States)

    Mosch, Heike L K S; Akintola, Oluseun; Plass, Winfried; Höppener, Stephanie; Schubert, Ulrich S; Ignaszak, Anna

    2016-05-10

    Carbon/polypyrrole (PPy) composites are promising electrode materials for energy storage applications such as lightweight capacitors. Although these materials are composed of relatively inexpensive components, there is a gap of knowledge regarding the correlation between surface, porosity, ion exchange dynamics, and the interplay of the double layer capacitance and pseudocapacitance. In this work we evaluate the specific surface area analyzed by the BET method and the area accessible for ions using electrochemical quartz-crystal microbalance (EQCM) for SWCNT/PPy and carbon black Vulcan XC72-R/PPy composites. The study revealed that the polymer has significant influence on the pore size of the composites. Although the BET surface is low for the polypyrrole, the electrode mass change and thus the electrochemical area are large for the polymer-containing electrodes. This indicates that multiple redox active centers in the charged polymer chain are good ion scavengers. Also, for the composite electrodes, the effective charge storage occurs at the polypyrrole-carbon junctions, which are easy to design/multiply by a proper carbon-to-polymer weight ratio. The specific BET surface and electrochemically accessible surface area are both important parameters in calculation of the electrode capacitance. SWCNTs/PPy showed the highest capacitances normalized to the BET and electrochemical surface as compared to the polymer-carbon black. TEM imaging revealed very homogeneous distribution of the nanosized polymer particles onto the CNTs, which facilitates the synergistic effect of the double layer capacitance (CNTs) and pseudocapacitance (polymer). The trend in the electrode mass change in correlation with the capacitance suggest additional effects such as a solvent co-insertion into the polymer and the contribution of the charge associated with the redox activity of oxygen-containing functional groups on the carbon surface.

  12. Case Studies on Using Strengths and Interests to Address the Needs of Students with Autism Spectrum Disorders

    Science.gov (United States)

    Lanou, Aaron; Hough, Lauren; Powell, Elizabeth

    2012-01-01

    Students on the autism spectrum present with difficulties in a variety of areas, including social understanding, emotional regulation, academics, and behavior. Professionals working in the field of autism must identify and address these areas of need given each individual child's specific cognitive profiles. In this article the authors highlight…

  13. MOF-templated synthesis of porous Co(3)O(4) concave nanocubes with high specific surface area and their gas sensing properties.

    Science.gov (United States)

    Lü, Yinyun; Zhan, Wenwen; He, Yue; Wang, Yiting; Kong, Xiangjian; Kuang, Qin; Xie, Zhaoxiong; Zheng, Lansun

    2014-03-26

    Porous metal oxides nanomaterials with controlled morphology have received great attention because of their promising applications in catalysis, energy storage and conversion, gas sensing, etc. In this paper, porous Co3O4 concave nanocubes with extremely high specific surface area (120.9 m(2)·g(-1)) were synthesized simply by calcining Co-based metal-organic framework (Co-MOF, ZIF-67) templates at the optimized temperature (300 °C), and the formation mechanism of such highly porous structures as well as the influence of the calcination temperature are well explained by taking into account thermal behavior and intrinsic structural features of the Co-MOF precursors. The gas-sensing properties of the as-synthesized porous Co3O4 concave nanocubes were systematically tested towards volatile organic compounds including ethanol, acetone, toluene, and benzene. Experimental results reveal that the porous Co3O4 concave nanocubes present the highest sensitivity to ethanol with fast response/recovery time (< 10 s) and a low detection limit (at least 10 ppm). Such outstanding gas sensing performance of the porous Co3O4 concave nanocubes benefits from their high porosity, large specific surface area, and remarkable capabilities of surface-adsorbed oxygen.

  14. Role of specific interfacial area in controlling properties of immiscible blends of biodegradable polylactide and poly[(butylene succinate)-co-adipate].

    Science.gov (United States)

    Ojijo, Vincent; Sinha Ray, Suprakas; Sadiku, Rotimi

    2012-12-01

    Binary blends of two biodegradable polymers: polylactide (PLA), which has high modulus and strength but is brittle, and poly[(butylene succinate)-co-adipate] (PBSA), which is flexible and tough, were prepared through batch melt mixing. The PLA/PBSA compositions were 100/0, 90/10, 70/30, 60/40, 50/50, 40/60, 30/70, 10/90, and 0/100. Fourier-transform infrared measurements revealed the absence of any chemical interaction between the two polymers, resulting in a phase-separated morphology as shown by scanning electron microscopy (SEM). SEM micrographs showed that PLA-rich blends had smaller droplet sizes when compared to the PBSA-rich blends, which got smaller with the reduction in PBSA content due to the differences in their melt viscosities. The interfacial area of PBSA droplets per unit volume of the blend reached a maximum in the 70PLA/30PBSA blend. Thermal stability and mechanical properties were not only affected by the composition of the blend, but also by the interfacial area between the two polymers. Through differential scanning calorimetry, it was shown that molten PBSA enhanced crystallization of PLA while the stiff PLA hindered cold crystallization of PBSA. Optimal synergies of properties between the two polymers were found in the 70PLA/30PBSA blend because of the maximum specific interfacial area of the PBSA droplets.

  15. 视神经脊髓炎谱系疾病伴常见非器官特异性自身抗体的特点%Neuromyelitis optica spectrum disorders with common non-organ-specific autoantibodies

    Institute of Scientific and Technical Information of China (English)

    孙昊; 汪春娟; 王戈; 王宝洁; 郭守刚

    2016-01-01

    Objective To investigate and compare the features between neuromyelitis optica spectrum disorders (NMOSD)with and without common non-organ-specific autoantibodies.Methods A total of 36 NMOSD patients were divided into 2 groups:positive group (n=26,with common non-organ-specific autoantibodies),and negative group (n=10,without common non-organ-specific autoantibodies).The clinical,laboratory and imaging features be-tween the two groups were assessed.Results Common non-organ-specific autoantibodies in NMOSD patients were mainly antinuclear antibody,anti-SSA antibody and anti-Ro52 antibody.The age of onset of the patients in the positive group were older than those in the negative group,and tended to complicate with non-organ-specific autoimmune disea-ses or tumors.As the initial symptoms,the ratio of optic neuritis/myelitis was higher in the negative group.While the cerebrospinal pressure and protein content were higher in the positive group.No differences were observed in other clini-cal,laboratory or MRI characteristics between the two groups.Conclusions NMOSD patients with non-organ-specific autoantibodies are vulnerable to severe inflammation in the central nervous system,non-organ-specific autoimmune disea-ses and tumors.%目的:探讨伴有及不伴常见非器官特异性自身抗体的视神经脊髓炎谱系疾病(NMOSD)患者的临床特点。方法收集36例NMOSD患者,其中伴有常见非器官特异性自身抗体者26例(阳性组),不伴常见非器官特异性自身抗体者10例(阴性组),比较两组临床表现、实验室检查及影像学特点。结果36例NMOSD患者中伴有至少一种常见非器官特异性自身抗体者占72.22%,并以抗核抗体、抗SSA抗体、抗Ro-52抗体为主。阳性组患者发病年龄晚于阴性组,且更易合并非器官特异性自身免疫疾病及肿瘤;阴性组患者首发症状中,视神经炎/脊髓炎比例明显高于阳性组,而阳

  16. Photosynthesis in relation to leaf nitrogen, phosphorus and specific leaf area of seedlings and saplings in tropical montane rain forests of Hainan Island, south China

    Institute of Scientific and Technical Information of China (English)

    Fude LIU; Ming ZHANG; Wenjin WANG; Shuning CHEN; Jianwei ZHENG; Wenjie YANG; Fengqin HU; Shuqing AN

    2009-01-01

    In order to make clear the relationships between photosynthesis and leaf N, leaf P and SLA of tropical trees, and test the differences in the relationships among life-form groups (trees, shrub-like trees and shrubs),seedlings and saplings of 101 species from a tropical montane rain forest, located in the Diaoluo Mountain of Hainan Island, were selected. The net photosynthesis based on area and mass (Aarea and Amass), leaf nitrogen content based on area and mass (Narea and Nmass), leaf phosphorus content based on area and mass (Parea and Pmass) and specific leaf area (SLA) were measured and/or calculated.The results showed that Aarea and Amass tended to follow the order of shrubs > trees > shrub-like trees. One-way ANOVA showed that the difference in Aarea between shrubs and shrub-like trees was significant (p 0.05). The relationship between Aarea and SLAwas highly significant in shrubs (p = 0.0006),trees (p 0.05). The relationships between Amass and leaf N and SLA were highly significant in all three life-form groups and for all species (p < 0.0001). For Amass and leaf P, there were significant correlations in tree groups (p =0.0377) and highly significant correlations in shrub groups (p = 0.0004), shrub-like tree groups (p = 0.0018) and for all species (p < 0.0001). Stepwise regression showed that predicted Amass values were closer to the observed values than those for predicted Aarea values. Thus, it can be concluded that the relationships obtained from seedling and sapling measurements are close to those from mature individuals; correlations between photosynthesis and Nmass, Pmass and SLA traits are significant and the relationships are stronger and more stable for A mass than for Aarea.

  17. Dynamic Spectrum Management for Military Wireless Networks

    Science.gov (United States)

    2010-09-01

    information society . The term “dynamic spectrum management” (DSM) covers a range of different subjects areas like dynamic channel allocation (DCA...the potential for the military to share spectrum spatially and temporally with multiple devices, 2003 (European Union) Information Society Technologies...E2ER) Project initiated in Information Society Technologies, 2005 (United States): DARPA XG and NSF projects complete a series of spectrum occupancy

  18. 煅烧高岭土的比表面积与吸油性能%Specific Surface Area and Oil Adsorption of Calcinated Kaolin Clay

    Institute of Scientific and Technical Information of China (English)

    孙涛; 陈洁渝; 周春宇; 雷新荣

    2013-01-01

    A washed kaolin clay was calcinated in the temperature range from 600 ℃ to 1 000 ℃. The microscopic morphology, the phase, the specific surface area and pore size distribution of the products were characterized by field emission scanning electron microscopy, X-ray diffraction and BET nitrogen adsorption measurement, respectively. The relationship between oil absorption and specific surface area was analyzed. The results show that the oil adsorption of calcinated kaolin clay with the smallest average pore size at 750 ℃ is the greatest (i.e., 80.272 g/100 g). The oil adsorption of calcinated kaolin clay became greater due to the larger specific surface area and the presence of the more concentrated micropore and mesopore in the pore distribution at the calcining temperature of < 800 ℃. The microporous occlusion of the kaolin clay occurred when calcinated at 800 ℃, causing the more concentrated mesopore and macropore in the pore distribution. As a result, the oil absorption reduced. The oil absorption of the calcinated kaolin clay was closely related to the specific surface area and the more concentrated micropore in the pore distribution.%以水洗高岭土为原料,在600~1 000℃,以50℃为间隔取点煅烧.通过场发射扫描电镜观察产品的微观形貌、X射线衍射仪分析产品的物相,并用BET物理吸附仪表征产品的比表面积和孔径分布,根据煅烧高岭土的微观形貌、物相组成、吸脱附等温线等,分析其比表面积与吸油性能的关系.结果表明:750℃的煅烧高岭土吸油值最高,为80.272 g/100g,此时煅烧高岭土的比表面积最大,孔径分布集中于微孔和中孔,平均孔径最小.煅烧温度低于800℃时,煅烧高岭土的孔径分布较集中于微孔和中孔,比表面积较大,吸油值较高;煅烧温度升高至800℃以后,高岭土发生烧结导致微孔闭塞,孔径分布向中孔和大孔集中,比表面积减小,吸油值较低.因而煅烧高岭土的吸油性

  19. Engaging general practitioners in public-private mix tuberculosis DOTS program in an urban area in Pakistan: need for context-specific approach.

    Science.gov (United States)

    Pethani, Amin; Zafar, Mubashir; Khan, Adeel Ahmed; Rabbani Sana, Unaib; Ahmed, Sana; Fatmi, Zafar

    2015-03-01

    A public-private mix tuberculosis (TB) DOTS project was implemented to enhance coverage and collaboration between the public and private sectors, with an objective to increase case detection and to improve TB case management in a large urban area. General practitioners (GPs) were trained to provide DOTS services. Patients were diagnosed and treated as per national guidelines and outcomes were reported to national TB control program. Treatment and sputum microscopy were provided free of cost. A total of 94 GPs were trained. In all, 57.4% of trained GPs remained actively involved in the project. Overall treatment success rate of the patients enrolled with the project was 86.3% with 8.7% default patients. Experience suggests that a more stringent selection criteria need to be followed for inclusion of GPs in the program to improve the success of the program. A multifaceted context specific approach is needed while working with private health care providers.

  20. Experimental characterization of the rectification process in ammonia-water absorption systems with a large-specific-area corrugated sheet structured packing

    Energy Technology Data Exchange (ETDEWEB)

    Sieres, Jaime; Fernandez-Seara, Jose; Uhia, Francisco J. [Area de Maquinas y Motores Termicos, E.T.S. de Ingenieros Industriales, Campus Lagoas-Marcosende No 9, 36310 Vigo, Pontevedra (Spain)

    2009-09-15

    In this paper, the mass transfer performance of a large-specific-area corrugated sheet structured packing for ammonia-water absorption refrigeration systems (AARS) is reported. An experimental facility was used to test the performance of the packing. Experimental results of the temperature, ammonia concentration and mass flow rate of the rectified vapour are presented and discussed for different operating conditions including reflux ratio values from 0.2 to 1. The volumetric vapour phase mass transfer coefficient is calculated from the measured data and compared with different correlations found in the literature. A new correlation is proposed which was fitted from the experimental data. Finally, a comparison is made between the actual packing height used in the experimental setup and the height required to obtain the same ammonia rectification in AARS with different packings previously tested by the authors. (author)

  1. Simulation of the specific surface area of snow using a one-dimensional physical snowpack model: implementation and evaluation for subarctic snow in Alaska

    Directory of Open Access Journals (Sweden)

    H. W. Jacobi

    2009-09-01

    Full Text Available The specific surface area (SSA of the snow constitutes a powerful parameter to quantify the exchange of matter and energy between the snow and the atmosphere. However, currently no snow physics model can simulate the SSA. Therefore, two different types of empirical parameterizations of the specific surface area (SSA of snow are implemented into the existing one-dimensional snow physics model CROCUS. The parameterizations are either based on diagnostic equations relating the SSA to parameters like snow type and density or on prognostic equations that describe the change of SSA depending on snow age, snowpack temperature, and the temperature gradient within the snowpack. Simulations with the upgraded CROCUS model were performed for a subarctic snowpack, for which an extensive data set including SSA measurements is available at Fairbanks, Alaska for the winter season 2003/2004. While a reasonable agreement between simulated and observed SSA values is obtained using both parameterizations, the model tends to overestimate the SSA. This overestimation is more pronounced using the diagnostic equations compared to the results of the prognostic equations. Parts of the SSA deviations using both parameterizations can be attributed to differences between simulated and observed snow heights, densities, and temperatures. Therefore, further sensitivity studies regarding the thermal budget of the snowpack were performed. They revealed that reducing the heat conductivity of the snow or increasing the turbulent fluxes at the snow surfaces leads to a slight improvement of the simulated thermal budget of the snowpack compared to the observations. However, their impact on further simulated parameters like snow height and SSA remains small. Including additional physical processes in the snow model may have the potential to advance the simulations of the thermal budget of the snowpack and, thus, the SSA simulations.

  2. Simulation of the specific surface area of snow using a one-dimensional physical snowpack model: implementation and evaluation for subarctic snow in Alaska

    Science.gov (United States)

    Jacobi, H.-W.; Domine, F.; Simpson, W. R.; Douglas, T. A.; Sturm, M.

    2010-01-01

    The specific surface area (SSA) of the snow constitutes a powerful parameter to quantify the exchange of matter and energy between the snow and the atmosphere. However, currently no snow physics model can simulate the SSA. Therefore, two different types of empirical parameterizations of the specific surface area (SSA) of snow are implemented into the existing one-dimensional snow physics model CROCUS. The parameterizations are either based on diagnostic equations relating the SSA to parameters like snow type and density or on prognostic equations that describe the change of SSA depending on snow age, snowpack temperature, and the temperature gradient within the snowpack. Simulations with the upgraded CROCUS model were performed for a subarctic snowpack, for which an extensive data set including SSA measurements is available at Fairbanks, Alaska for the winter season 2003/2004. While a reasonable agreement between simulated and observed SSA values is obtained using both parameterizations, the model tends to overestimate the SSA. This overestimation is more pronounced using the diagnostic equations compared to the results of the prognostic equations. Parts of the SSA deviations using both parameterizations can be attributed to differences between simulated and observed snow heights, densities, and temperatures. Therefore, further sensitivity studies regarding the thermal budget of the snowpack were performed. They revealed that reducing the thermal conductivity of the snow or increasing the turbulent fluxes at the snow surfaces leads to a slight improvement of the simulated thermal budget of the snowpack compared to the observations. However, their impact on further simulated parameters like snow height and SSA remains small. Including additional physical processes in the snow model may have the potential to advance the simulations of the thermal budget of the snowpack and, thus, the SSA simulations.

  3. Area-specific information processing in prefrontal cortex during a probabilistic inference task: a multivariate fMRI BOLD time series analysis.

    Directory of Open Access Journals (Sweden)

    Charmaine Demanuele

    Full Text Available Discriminating spatiotemporal stages of information processing involved in complex cognitive processes remains a challenge for neuroscience. This is especially so in prefrontal cortex whose subregions, such as the dorsolateral prefrontal (DLPFC, anterior cingulate (ACC and orbitofrontal (OFC cortices are known to have differentiable roles in cognition. Yet it is much less clear how these subregions contribute to different cognitive processes required by a given task. To investigate this, we use functional MRI data recorded from a group of healthy adults during a "Jumping to Conclusions" probabilistic reasoning task.We used a novel approach combining multivariate test statistics with bootstrap-based procedures to discriminate between different task stages reflected in the fMRI blood oxygenation level dependent signal pattern and to unravel differences in task-related information encoded by these regions. Furthermore, we implemented a new feature extraction algorithm that selects voxels from any set of brain regions that are jointly maximally predictive about specific task stages.Using both the multivariate statistics approach and the algorithm that searches for maximally informative voxels we show that during the Jumping to Conclusions task, the DLPFC and ACC contribute more to the decision making phase comprising the accumulation of evidence and probabilistic reasoning, while the OFC is more involved in choice evaluation and uncertainty feedback. Moreover, we show that in presumably non-task-related regions (temporal cortices all information there was about task processing could be extracted from just one voxel (indicating the unspecific nature of that information, while for prefrontal areas a wider multivariate pattern of activity was maximally informative.We present a new approach to reveal the different roles of brain regions during the processing of one task from multivariate activity patterns measured by fMRI. This method can be a valuable

  4. Theoretical and experimental substantiation of a thermogravimetric method for assessing the water-retention capacity and specific surface area of disperse systems

    Science.gov (United States)

    Smagin, A. V.; Sadovnikova, N. B.; Bashina, A. S.; Kirichenko, A. V.; Vityazev, V. G.

    2016-12-01

    A conceptually new instrumental method has been proposed for the determination of the sorption fragment of the soil water retention curve and the specific surface area of soils and sediments by drying samples at different temperatures, which is based on fundamental models for relative air humidity and thermodynamic water potential ( Ψ) as functions of temperature ( T). The basic equation for the calculation of water potential in the first (linear) approximation is as follows: Ψ = Q- aT, where Q is the specific heat of evaporation, and a is the physically substantiated parameter related to the initial relative air humidity in the laboratory. The setting of model parameters necessary for quantitative calculations has been performed from tabulated data for the saturated water vapor pressure as a function of temperature and results of an independent experiment with gradual air heating and synchronous automated control of air humidity and temperature with DS 1923 hydrochrons. The potentialities of the method have been demonstrated using literature data on the dehydration of soil colloids and our own results on the drying of a silty sandy soil (Arenosol) from Dubai, a light loamy soddy-podzolic soil (Albic Retisol) and a low-moor peat soil (Histosol) from Moscow oblast, and a loamy ordinary chernozem (Haplic Chernozem) from Krasnodar region.

  5. Spectrum Analysis of Wind Profiling Radar Measurements

    Institute of Scientific and Technical Information of China (English)

    阮征; 慕瑞琪; 魏鸣; 葛润生

    2014-01-01

    Unlike previous studies on wind turbulence spectrum in the planetary boundary layer, this investigation focuses on high-altitude (1-5 km) wind energy spectrum and turbulence spectrum under various weather conditions. A fast Fourier transform (FFT) is used to calculate the wind energy and turbulence spectrum density at high altitudes (1-5 km) based on wind profiling radar (WPR) measurements. The turbulence spectrum under stable weather conditions at high altitudes is expressed in powers within a frequency range of 2 × 10-5-10-3 s-1, and the slope b is between -0.82 and -1.04, indicating that the turbulence is in the transition from the energetic area to the inertial sub-range. The features of strong weather are reflected less obviously in the wind energy spectrum than in the turbulence spectrum, with peaks showing up at different heights in the latter spectrum. Cold windy weather appears over a period of 1.5 days in the turbulence spectrum. Wide-range rainstorms exhibit two or three peaks in the spectrum over a period of 15-20 h, while in severe convective weather conditions, there are two peaks at 13 and 9 h. The results indicate that spectrum analysis of wind profiling radar measurements can be used as a supplemental and helpful method for weather analysis.

  6. Autistic spectrum disorders.

    Science.gov (United States)

    Singhania, Rajeshree

    2005-04-01

    Autistic spectrum disorders is a complex developmental disorder with social and communication dysfunction at its core. It has a wide clinical spectrum with a common triad of impairments -- social communication, social interaction and social imagination. Even mild or subtle difficulties can have a profound and devastating impact on the child. To be able to provide suitable treatments and interventions the distinctive way of thinking and learning of autistic children has to be understood. The core areas of social, emotional, communication and language deficits have to be addressed at all levels of functioning. The important goals of assessment include a categorical diagnosis of autism that looks at differential diagnosis, a refined precise documentation of the child's functioning in various developmental domains and ascertaining presence of co-morbid conditions. The interventions have to be adapted to the individual's chronological age, developmental phase and level of functioning. The strategies of curriculum delivery and teaching the child with autism is distinctive and includes presence of structure to increase predictability and strategies to reduce arousal of anxiety.

  7. Current Noise Spectrum of a Quantum Shuttle

    DEFF Research Database (Denmark)

    Flindt, Christian; Novotny, T.; Jauho, Antti-Pekka

    2005-01-01

    We present a method for calculating the full current noise spectrum S(omega) for the class of nano-electromechanical systems (NEMS) that can be described by a Markovian generalized master equation. As a specific example we apply the method to a quantum shuttle. The noise spectrum of the shuttle h...

  8. Area-specific effects of brain-derived neurotrophic factor (BDNF) genetic ablation on various neuronal subtypes of the mouse brain.

    Science.gov (United States)

    Grosse, Gisela; Djalali, Susann; Deng, Dong Rui; Höltje, Markus; Hinz, Britta; Schwartzkopff, Katharina; Cygon, Marcel; Rothe, Thomas; Stroh, Thomas; Hellweg, Rainer; Ahnert-Hilger, Gudrun; Hörtnag, Heide

    2005-05-12

    The effects of brain-derived neurotrophic factor (BDNF) on the development of presynaptic terminals and of neuronal subtypes in various brain areas were studied in BDNF-knockout (BDNF-/-) mice at postnatal days 15-17. Western analysis revealed no changes in the overall amount of a variety of synaptic proteins in BDNF-/- mice as compared to wild type mice. In addition, the complex between the vesicular proteins, synaptophysin and synaptobrevin, as well as their respective homodimers were unaltered. Moreover, no changes in the density of neurons were found in, e.g., the CA3 region of the hippocampus and the nucleus nervi facialis of BDNF-/- mice. However, cholinergic cells were reduced by 20% in the medial septum of BDNF-/- mice associated with a decrease in the activity of choline acetyltransferase and protein levels of nerve growth factor in the hippocampus by 16% and 44%, respectively. In the striatum, however, the total number of cholinergic cells were comparable in both groups, although the activity of choline acetyltransferase was decreased by 46%. In GABAergic interneurons, the expression of neuropeptides in various brain areas was differentially affected by BDNF deletion as revealed by immunohistochemistry. In the hippocampus and cortex of BDNF-/- mice, the density of neuropeptide Y-, somatostatin-, and parvalbumin-immunoreactive cells was drastically reduced, whereas the density of calretinin-positive cells was increased. The extent of these changes in neuropeptide-containing cells varied among hippocampal subregions. In the striatum, only the density of parvalbumin-immunoreactive cells was decreased by approximately 45%. In conclusion, BDNF deficiency is accompanied by a differential dysregulation in the expression of neuropeptides and calcium-binding proteins in otherwise intact GABAergic and glutamatergic neurons in a region-specific manner.

  9. Analysis of results related to the percent free prostate specific antigen among men without prostate diseases in Xi'an area

    Institute of Scientific and Technical Information of China (English)

    Peng Zhang; Ziming Wang; Tie Chong; Lihua Zhao

    2007-01-01

    Objective: To measure the percent of free prostate specific antigen (fPSA) among men without prostate diseases in Xi'an area, and to study the relationship of percent fPSA with age and pathological grade, clinical stage of prostate cancer (PCa) with percent fPSA, and to analyze the difference between the data in China and theoverseas data to determine appropriate reference range for Chinese male. Methods: A total of 713 participants were enrolled into the study, with PSA, fPSA in serum measured and the percent fPSA calculated. Out of 713 cases, 679 without prostate diseases were divided into 5 groups by age, and then the relationships of PSA, fPSA and percent fPSA with age were studied, respectively. The relationship of pathological grade and clinical stage with percent fPSA of the 34 participants with PCa was also studied. With the help of the related data of men without prostate disease, the appropriate reference range for Chinese male was established. Results: The increases in PSA or fPSA were correlated with age, while there was no significant correlation between age and percent fPSA. The percent fPSA was also correlated with pathological grade and clinical stage of PCa. The percent fPSA of men without prostate disease in Xi'an area was significantly lower than that in the related overseas data. The reference range of percent fPSA for Chinese male was≥15%. Conclusion: Percent fPSA might be more useful than PSA in the detection of prostate cancer. As the percent fPSA is decreased, the pathological grade is decreased, and the clinical stage is increased, the malignant degree is increased. The reference range of≥15% is more appropriate for Chinese male.

  10. Rotational Spectrum of Tryptophan

    Science.gov (United States)

    Sanz, M. Eugenia; Cabezas, Carlos; Mata, Santiago; Alonso, José L.

    2014-06-01

    The rotational spectrum of the natural amino acid tryptophan has been observed using a recently constructed LA-MB-FTMW spectrometer, specifically designed to optimize the detection of heavier molecules at a lower frequency range. Independent analyses of the rotational spectra of individual conformers have conducted to a definitive identification of two different conformers of tryptophan, with one of the observed conformers never reported before. The experimental values of the 14N nuclear quadrupole coupling constants have been found capital in the discrimination of the conformers. Both observed conformers are stabilized by a O-H\\cdotsN hydrogen bond in the side chain and a N-H\\cdotsπ interaction forming a chain that reinforces the strength of hydrogen bonds through cooperative effects.

  11. Information technology -- Local and metropolitan area networks -- Token ring access method and physical layer specifications -- Recommended practice for use of unshielded twisted pair cable (UTP) for token ring data transmission at 4-Mbit/s

    CERN Document Server

    International Organization for Standardization. Geneva

    1993-01-01

    Information technology -- Local and metropolitan area networks -- Token ring access method and physical layer specifications -- Recommended practice for use of unshielded twisted pair cable (UTP) for token ring data transmission at 4-Mbit/s

  12. 具有高比表面积的稻壳灰的制备及其化学活性的研究%Study on Preparation of Rice Husk Ash with High Specific Surface Area and Its Chemical Reactivity

    Institute of Scientific and Technical Information of China (English)

    冯庆革; 林清宇; 童张法; S.Sugita

    2004-01-01

    Preparation of rice husk ash with high specific surface area and chemical reactivity of the product are reported in this paper. The amorphous rice husk ash with high specific surface area of 311 m2·g-1 was produced by heating acid treated rice husk at 700℃ for 4 h. The isotherms of rice husk ash are similar in shape to type Ⅱof Brunaner's classification with mesopores being predominant. The rice husk ash has a high chemical reactivity,especially that pretreated with acid. This chemical reactivity depends on ashing temperature and pretreatment conditions. There is an exponential relation between the specific surface area of rice husk ash and the change in the conductivity of saturated Ca(OH)2 solution with rice husk ash, from which the specific surface area can be known according to the conductivity change.

  13. Measuring the specific surface area of snow with X-ray tomography and gas adsorption: comparison and implications for surface smoothness

    Directory of Open Access Journals (Sweden)

    M. Kerbrat

    2008-03-01

    Full Text Available Chemical and physical processes, such as heterogeneous chemical reactions, light scattering, and metamorphism occur in the natural snowpack. To model these processes in the snowpack, the specific surface area (SSA is a key parameter. In this study, two methods, computed tomography and methane adsorption, which have intrinsically different effective resolutions – molecular and 30 μm, respectively – were used to determine the SSA of similar natural snow samples. Except for very fresh snow, the two methods give identical results, with an uncertainty of 3%. This implies that the surface of aged natural snow is smooth up to a scale of about 30 μm and that if smaller structures are present they do not contribute significantly to the overall SSA. It furthermore implies that for optical methods a voxel size of 10 μm is sufficient to capture all structural features of this type of snow; however, fresh precipitation appears to contain small features that cause an under-estimation of SSA with tomography at this resolution. The methane adsorption method is therefore superior to computed tomography for very fresh snow having high SSA. Nonetheless, in addition to SSA determination, tomography provides full geometric information about the ice matrix. It can also be advantageously used to investigate layered snow packs, as it allows measuring SSA in layers of less than 1 mm.

  14. Relationship between the specific surface area of rust and the electrochemical behavior of rusted steel in a wet-dry acid corrosion environment

    Science.gov (United States)

    Liu, Wei; Zhao, Qing-he; Li, Shuan-zhu

    2017-01-01

    The relationship between the specific surface area (SSA) of rust and the electrochemical behavior of rusted steel under wet-dry acid corrosion conditions was investigated. The results showed that the corrosion current density first increased and then decreased with increasing SSA of the rust during the corrosion process. The structure of the rust changed from single-layer to double-layer, and the γ-FeOOH content decreased in the inner layer of the rust with increasing corrosion time; by contrast, the γ-FeOOH content in the outer layer was constant. When the SSA of the rust was lower than the critical SSA corresponding to the relative humidity during the drying period, condensed water in the micropores of the rust could evaporate, which prompted the diffusion of O2 into the rust and the following formation process of γ-FeOOH, leading to an increase of corrosion current density with increasing corrosion time. However, when the SSA of the rust reached or exceeded the critical SSA, condensate water in the micro-pores of the inner layer of the rust could not evaporate which inhibited the diffusion of O2 and decreased the γ-FeOOH content in the inner rust, leading to a decrease of corrosion current density with increasing corrosion time.

  15. Geophysical Logs, Specific Capacity, and Water Quality of Four Wells at Rogers Mechanical (former Tate Andale) Property, North Penn Area 6 Superfund Site, Lansdale, Pennsylvania, 2006-07

    Science.gov (United States)

    Senior, Lisa A.; Bird, Philip H.

    2010-01-01

    As part of technical assistance to the U.S. Environmental Protection Agency (USEPA) in the remediation of properties on the North Penn Area 6 Superfund Site in Lansdale, Pa., the U.S. Geological Survey (USGS) in 2006-07 collected data in four monitor wells at the Rogers Mechanical (former Tate Andale) property. During this period, USGS collected and analyzed borehole geophysical and video logs of three new monitor wells (Rogers 4, Rogers 5, and Rogers 6) ranging in depth from 80 to 180 feet, a borehole video log and additional heatpulse-flowmeter measurements (to quantify vertical borehole flow) in one existing 100-foot deep well (Rogers 3S), and water-level data during development of two wells (Rogers 5 and Rogers 6) to determine specific capacity. USGS also summarized results of passive-diffusion bag sampling for volatile organic compounds (VOCs) in the four wells. These data were intended to help understand the groundwater system and the distribution of VOC contaminants in groundwater at the property.

  16. Comments on the article by A. J. Lecloux (J Nanopart Res (2015) 17:447) regarding the use of volume-specific surface area (VSSA) to classify nanomaterials

    Science.gov (United States)

    Gibson, Neil; Rauscher, Hubert; Roebben, Gert

    2016-08-01

    In November 2015, an article by A. J. Lecloux was published in this journal (J Nanopart Res, 17:447, 2015). The article focused on the use of volume-specific surface area (VSSA) for the implementation of the European Commission's recommended definition of "nanomaterial". In that paper, VSSA values were calculated for polydisperse particulate materials using a particle number-based averaging method which do not agree with earlier results of VSSA simulations of polydisperse materials reported in 2014 by the Joint Research Centre (JRC) of the European Commission (EC). In this contribution, we explain the difference between traditional view of VSSA which was used by the JRC and the proposed model of Lecloux. Through the use of some simple examples for polydisperse materials, it is demonstrated that the latter produces values which neither correspond to the generally accepted definition of VSSA nor relate to the commonly used experimental methods for determining VSSA using gas adsorption. Lecloux's model therefore does not constitute a basis for practical implementation of the EC's definition of nanomaterial using gas adsorption techniques.

  17. The Biokinetic Spectrum for Temperature.

    Directory of Open Access Journals (Sweden)

    Ross Corkrey

    Full Text Available We identify and describe the distribution of temperature-dependent specific growth rates for life on Earth, which we term the biokinetic spectrum for temperature. The spectrum has the potential to provide for more robust modeling in thermal ecology since any conclusions derived from it will be based on observed data rather than using theoretical assumptions. It may also provide constraints for systems biology model predictions and provide insights in physiology. The spectrum has a Δ-shape with a sharp peak at around 42°C. At higher temperatures up to 60°C there was a gap of attenuated growth rates. We found another peak at 67°C and a steady decline in maximum rates thereafter. By using Bayesian quantile regression to summarise and explore the data we were able to conclude that the gap represented an actual biological transition between mesophiles and thermophiles that we term the Mesophile-Thermophile Gap (MTG. We have not identified any organism that grows above the maximum rate of the spectrum. We used a thermodynamic model to recover the Δ-shape, suggesting that the growth rate limits arise from a trade-off between activity and stability of proteins. The spectrum provides underpinning principles that will find utility in models concerned with the thermal responses of biological processes.

  18. Gene-specific of endocannabinoid receptor 1 (cnr1a) by ethanol probably leads to the development of fetal alcohol spectrum disorder (FASD) phenotypes in Japanese rice fish (Oryzias latipes) embryogenesis

    Science.gov (United States)

    Developmental ethanol exposure is able to induce Fetal Alcohol Spectrum Disorder (FASD) phenotypes in Japanese rice fish (Oryzias latipes). This study investigated possible differential expression of cannabinoid receptor (cnr) mRNAs during Japanese rice fish embryogenesis and variability to ethanol-...

  19. Biogenic volatile organic compound (BVOC) emissions from forested areas in Turkey: Determination of specific emission rates for thirty-one tree species

    Energy Technology Data Exchange (ETDEWEB)

    Aydin, Yagmur Meltem; Yaman, Baris; Koca, Husnu; Dasdemir, Okan; Kara, Melik; Altiok, Hasan; Dumanoglu, Yetkin; Bayram, Abdurrahman [Department of Environmental Engineering, Faculty of Engineering, Dokuz Eylul University, Tinaztepe Campus, Buca, Izmir (Turkey); Tolunay, Doganay [Department of Soil Science and Ecology, Faculty of Forestry, Istanbul University, Bahcekoy, Istanbul (Turkey); Odabasi, Mustafa [Department of Environmental Engineering, Faculty of Engineering, Dokuz Eylul University, Tinaztepe Campus, Buca, Izmir (Turkey); Elbir, Tolga, E-mail: tolga.elbir@deu.edu.tr [Department of Environmental Engineering, Faculty of Engineering, Dokuz Eylul University, Tinaztepe Campus, Buca, Izmir (Turkey)

    2014-08-15

    Normalized biogenic volatile organic compound (BVOC) emission rates for thirty one tree species that cover the 98% of national forested areas in Turkey were determined. Field samplings were performed at fourteen different forested areas in Turkey using a specific dynamic enclosure system. The selected branches of tree species were enclosed in a chamber consisted of a transparent Nalofan bag. The air-flows were sampled from both inlet and outlet of the chamber by Tenax-filled sorbent tubes during photosynthesis of trees under the presence of sunlight. Several environmental parameters (temperature, humidity, photosynthetically active radiation-PAR, and CO{sub 2}) were continuously monitored inside and outside the enclosure chamber during the samplings. Collected samples were analyzed using a gas chromatography mass spectrometry (GC/MS) system equipped with a thermal desorber (TD). Sixty five BVOCs classified in five major groups (isoprene, monoterpenes, sesquiterpenes, oxygenated sesquiterpenes, and other oxygenated compounds) were analyzed. Emission rates were determined by normalization to standard conditions (1000 μmol/m{sup 2} s PAR and 30 °C temperature for isoprene and 30 °C temperature for the remaining compounds). In agreement with the literature, isoprene was mostly emitted by broad-leaved trees while coniferous species mainly emitted monoterpenes. Several tree species such as Sweet Chestnut, Silver Lime, and European Alder had higher monoterpene emissions although they are broad-leaved species. High isoprene emissions were also observed for a few coniferous species such as Nordmann Fir and Oriental Spruce. The highest normalized total BVOC emission rate of 27.1 μg/g h was observed for Oriental Plane while South European Flowering Ash was the weakest BVOC emitter with a total normalized emission rate of 0.031 μg/g h. Monoterpene emissions of broad-leaved species mainly consisted of sabinene, limonene and trans-beta-ocimene, while alpha-pinene, beta

  20. Aeroallergen spectrum of patients with allergic rhinitis in Enshi area%恩施州地区变应性鼻炎患者的吸入变应原谱分析

    Institute of Scientific and Technical Information of China (English)

    刘军; 周意; 万静; 刘忠

    2011-01-01

    目的:调查恩施州地区变应性鼻炎患者变应原的分布,并分析其相关因素.方法:应用13种标准化吸入变应原对463例疑似变应性鼻炎患者进行皮肤点刺实验,并详细采集病史资料.结果:387例(83.6%)患者变应原呈阳性反应,阳性率相对较高的变应原依次为粉尘螨、屋尘螨、热带螨、美洲大蠊、德国小蠊及狗毛.对单类变应原呈阳性反应的占51.9%,其中大多数是螨类,占49.6%.变应原阳性强弱与家族史、是否伴哮喘、年龄及居住环境显著相关.结论:恩施州地区变应性鼻炎的主要变应原为尘螨,其阳性强弱与遗传、哮喘、年龄及居住环境有关.%Objective: To investigate aeroallergen spectrum of patients with allergic rhinitis in Enshi area and analyze its related factors. Method:Skin prick test was carried out in 463 patients with allergic rhinitis with 13 inhaled allergens. Detailed history was collected in all cases. Result: Three hundred and eigty-seven cases(83. 6 %)showed positive reaction to at least one allergen of 13 allergens. The most common allergens found in patients were dermatophagoides farinae and dermatophagoides pteronyssinus, followed by tropical mite、periplaneta americana,blattella germanica and dog hair. The positive reaction rate of single specie allergen were 51.9%, and most of them was positive to mites(49. 6 %). The positive reaction degree was significantly related to family history, asthma ,age and housing enviroment. Conclusion:The major allergen of allergic rhinitis was mite. The positive reaction degree related to genetics, asthma, age and housing enviroment.

  1. An efficient method for applying a differential equation to deriving the spatial distribution of specific catchment area from gridded digital elevation models

    Science.gov (United States)

    Qin, Cheng-Zhi; Ai, Bei-Bei; Zhu, A.-Xing; Liu, Jun-Zhi

    2017-03-01

    Deriving the spatial distribution of specific catchment area (SCA) from a gridded digital elevation model (DEM) is one of the most important issues in digital terrain analysis. Conventional methods usually estimate SCA for each cell using a flow direction algorithm, but the results obtained are often unsatisfactory. Recently, Gallant and Hutchinson (2011, Water Resources Research, 47(5), W05535) proposed a differential equation which quantifies the change of SCA along a slope line, and thus the numerical solution of SCA at any point on a surface can be calculated accurately by integrating the differential equation. However, obtaining the numerical SCA solution based on this differential equation is so computationally intensive that it is too time-consuming to use it to derive the overall SCA spatial distribution from a gridded DEM. In this study, we developed a parallel algorithm based on OpenMP to make the numerical SCA solution based on Gallant and Hutchinson (2011)'s differential equation practical to derive the spatial distribution of SCA from a gridded DEM. Experiments based on two artificial surfaces with theoretical SCA and a more complex real terrain surface demonstrated that the proposed parallel algorithm obtained satisfactory acceleration performance and a much lower error than the MFD-md algorithm, which is a representative of conventional grid-based flow direction algorithms. Due to the speedup effects of the proposed parallel algorithm, we analyzed the effects of the DEM grid size and integration step length on the numerical SCA solution in detailed experiments. The experimental results suggested that the proposed algorithm performed best normally at the resolution of 5 m. A step ratio of 0.5 is suitable in applications of the proposed parallel algorithm.

  2. Area-specific modulation of neural activation comparing escitalopram and citalopram revealed by pharmaco-fMRI: a randomized cross-over study.

    Science.gov (United States)

    Windischberger, Christian; Lanzenberger, Rupert; Holik, Alexander; Spindelegger, Christoph; Stein, Patrycja; Moser, Ulrike; Gerstl, Florian; Fink, Martin; Moser, Ewald; Kasper, Siegfried

    2010-01-15

    Area-specific and stimulation-dependent changes of human brain activation by selective serotonin reuptake inhibitors (SSRI) are an important issue for improved understanding of treatment mechanisms, given the frequent prescription of these drugs in depression and anxiety disorders. The aim of this neuroimaging study was to investigate differences in BOLD-signal caused by administration of the SSRIs escitalopram and citalopram using pharmacological functional magnetic resonance imaging (pharmaco-fMRI). Eighteen healthy subjects participated in a placebo-controlled, randomized, double-blind study in cross-over repeated measures design. Each volunteer performed facial emotional discrimination and a sensorimotor control paradigm during three scanning sessions. Citalopram (20 mg/d), escitalopram (10 mg/d) and placebo were administered for 10 days each with a drug-free period of at least 21 days. Significant pharmacological effects on BOLD-signal were found in the amygdala, medial frontal gyrus, parahippocampal, fusiform and middle temporal gyri. Post-hoc t-tests revealed decreased BOLD-signal in the right amygdala and left parahippocampal gyrus in both pharmacological conditions, compared to placebo. Escitalopram, compared to citalopram, induced a decrease of BOLD-signal in the medial frontal gyrus and an increase in the right fusiform and left parahippocampal gyri. Drug effects were concentrated in brain regions with dense serotonergic projections. Both escitalopram and citalopram attenuated BOLD-signal in the amygdala and parahippocampal cortex to emotionally significant stimuli compared to control stimuli. We believe that reduced reactivity in the medial frontal gyrus found for escitalopram compared to citalopram administration might explain the response differences between study drugs as demonstrated in previous clinical trials.

  3. Aeroallergen spectrum of patients with child allergic rhinitis in Changsha area of China%长沙地区562例变应性鼻炎患儿变应原谱分析

    Institute of Scientific and Technical Information of China (English)

    钟竹青; 王芳; 王天生; 李亮明; 谭国林

    2011-01-01

    目的:调查长沙地区变应性鼻炎患儿的变应原分布情况及其阳性率,并分析其相关因素.方法:应用13种标准化吸入变应原对562例变应性鼻炎患儿进行变应原皮肤点刺试验,并详细采集病史资料.结果:457例呈阳性反应(81.3%),其主要变应原均为粉尘螨和屋尘螨,其次为热带螨、美洲大蠊、德国小蠊及狗毛等.花粉变应原在该组十分少见,城市儿童变应性鼻炎的患病率显著高于农村(P<0.01).结论:长沙地区变应性鼻炎患儿的主要变应原为尘螨,与居住环境有关,多数患儿可应用螨变应原进行特异性免疫治疗.变应原皮肤点刺试验应用于儿童变应性鼻炎的诊断是一种安全的方法.%Objective:To investigate aeroallergen spectrum and allergy positive rates of patients with child allergic rhinitis and analyze its related factors. Method:Skin prick test was carried out in 562 cases with child allergic rhinitis using 13 inhaled allergens, and detailed history was collected in all cases. Result: Four hundred and fifty-seven (81. 3%) of 562 cases showed positive reaction to at least one allergen out of 13 allergens. The most common allergens found in patients was dermatophagoides farinae and dermatophagoides pteronyssinus,and positive reaction was 93. 1% in child allergic rhinitis, followed by tropical mite, periplaneta americana, blattella germanica and dog hair. The pollen allergen, most common in American and European, was pretty rare in this study. The prevalence of child allergic rhinitis was significantly higher in urban than in rural(P<0. 01). There was no adverse effect appeared in children with allergic rhinitis underwent skin prick test. Conclusion: The major allergen of allergic rhinitis is mite for child allergic rhinitis, and relates to housing enviroment. Most of patients with child allergic rhinitis can be treated by the mite specific immunotherapy. The skin prick test is a safe technique for diagnosis of

  4. Imaging spectrum of neurocysticercosis

    Directory of Open Access Journals (Sweden)

    Jing-Long Zhao

    2015-03-01

    Full Text Available Neurocysticercosis is the most common parasitic disease of the central nervous system, and also one of the most common causes of seizures in endemic areas. Globalization has caused the disease to spread around the world beyond the endemic regions. With no specific clinical symptoms of the disease, medical imaging plays an important role in the diagnosis of neurocysticercosis. Familiarity with these imaging findings may help greatly in early diagnosis, appropriate treatment decision, and follow-up of patients with neurocysticercosis.

  5. CMOS RF Transceiver condiderations for Dynamic Spectrum Access

    NARCIS (Netherlands)

    Oude Alink, M.S.; Klumperink, E.A.M.; Kokkeler, A.B.J.; Smit, G.J.M.; Nauta, B.

    2012-01-01

    Cognitive Radio (CR), and in particular dynamic spectrum access (DSA), promises a much more efficient use of the spectrum by opportunistically using available frequencies. This asks for specific functionality, like spectrum sensing and frequency-agile transmission and reception. We will show that th

  6. Psychotherapy for Anxiety in Children With Autism Spectrum Disorder

    Science.gov (United States)

    2016-11-28

    Autism Spectrum Disorders; Autism; Asperger's Syndrome; Pervasive Developmental Disability - Not Otherwise Specified; Obsessive-compulsive Disorder; Social Phobia; Generalized Anxiety Disorder; Specific Phobia; Separation Anxiety Disorder

  7. Schizophrenia Spectrum and Attention-Deficit/Hyperactivity Disorder Symptoms in Autism Spectrum Disorder and Controls

    Science.gov (United States)

    Gadow, Kenneth D.

    2012-01-01

    Objective: This study compared the differential severity of specific symptoms of schizophrenia spectrum disorder (SSD) in children with autism spectrum disorder (ASD) and child psychiatry outpatient referrals (controls). Each group was further subdivided into subgroups with and without co-occurring attention-deficit/hyperactivity disorder (ADHD).…

  8. 福州市常见植物比叶面积研究%Research on the Specific Leaf Area of Common Plants in Fuzhou City

    Institute of Scientific and Technical Information of China (English)

    程栋梁; 林娜

    2009-01-01

    [目的]研究不同植物的比叶面积与叶生物量的相关关系.[方法]以福州市24种常见绿化植物为试验对象,测定了其叶片干鲜重、叶面积及比叶面积并研究了不同物种的比叶面积对生物量增加的响应模式.[结果]回归分析表明,所有试验植物的叶面积(L_A)与叶生物量(L_M)均呈极显著正相关关系,6种植物在L_A与L_M之间的异速生长指数大于1.0,18种植物的异速生长指数小于1.0,24个植物物种异速生长指数的平均值为0.96.L_A与(L_M)0.94成正比.所有试验植物的叶片水分含量(M_W)与L_M均呈极显著正相关关系,8种植物在M_W与L_M之间的异速生长指数大于1.0,2种植物的异速生长指数为1.0,14种植物的异速生长指数小于1.0.M_W与(L_M)0.96成正比.[结论]不同物种的叶面积和叶生物量之间的异速生长指数和常数存在显著差异.%[Objective] The aim was to research the correlations between specific leaf area (SLA) and leaf biomass (L_M) of different plant species. [ Method] With the 24 common greening plant species in Fuzhou City as test objects,their dry and fresh leaf weights, leaf areas (L_A) and SLA were measured and the response models of SLA to biomass increasing of different species were researched. [ Result] The regression analysis showed that the L_A of all the tested plants showed extremely significantly positive correlation with their L_M; the allometry indexes between L_A, and LM of 6 plant species were bigger than 1.0 and that of 18 plant species were smaller than 1.0; the average allometry index of the 24 plant species was 0.96. L_A was proportional to (L_M) ~(0.94). The water content in leaf ( M_W ) of all the tested plants showed extremely significantly positive correlation with their L_M; the allometry indexes between M_W and L_M of S plant species were bigger than 1.0.that of 2 plant species were 1.0 and that of 14 plant species were smaller than 1.0 M_W was proportional to (L_M)~(0

  9. Reduced uncertainty of regional scale CLM predictions of net carbon fluxes and leaf area indices with estimated plant-specific parameters

    Science.gov (United States)

    Post, Hanna; Hendricks Franssen, Harrie-Jan; Han, Xujun; Baatz, Roland; Montzka, Carsten; Schmidt, Marius; Vereecken, Harry

    2016-04-01

    Reliable estimates of carbon fluxes and states at regional scales are required to reduce uncertainties in regional carbon balance estimates and to support decision making in environmental politics. In this work the Community Land Model version 4.5 (CLM4.5-BGC) was applied at a high spatial resolution (1 km2) for the Rur catchment in western Germany. In order to improve the model-data consistency of net ecosystem exchange (NEE) and leaf area index (LAI) for this study area, five plant functional type (PFT)-specific CLM4.5-BGC parameters were estimated with time series of half-hourly NEE data for one year in 2011/2012, using the DiffeRential Evolution Adaptive Metropolis (DREAM) algorithm, a Markov Chain Monte Carlo (MCMC) approach. The parameters were estimated separately for four different plant functional types (needleleaf evergreen temperate tree, broadleaf deciduous temperate tree, C3-grass and C3-crop) at four different sites. The four sites are located inside or close to the Rur catchment. We evaluated modeled NEE for one year in 2012/2013 with NEE measured at seven eddy covariance sites in the catchment, including the four parameter estimation sites. Modeled LAI was evaluated by means of LAI derived from remotely sensed RapidEye images of about 18 days in 2011/2012. Performance indices were based on a comparison between measurements and (i) a reference run with CLM default parameters, and (ii) a 60 instance CLM ensemble with parameters sampled from the DREAM posterior probability density functions (pdfs). The difference between the observed and simulated NEE sum reduced 23% if estimated parameters instead of default parameters were used as input. The mean absolute difference between modeled and measured LAI was reduced by 59% on average. Simulated LAI was not only improved in terms of the absolute value but in some cases also in terms of the timing (beginning of vegetation onset), which was directly related to a substantial improvement of the NEE estimates in

  10. Seasonal variations of all-cause and cause-specific mortality by age, gender, and socioeconomic condition in urban and rural areas of Bangladesh

    Directory of Open Access Journals (Sweden)

    Burkart Katrin

    2011-08-01

    Full Text Available Abstract Background Mortality exhibits seasonal variations, which to a certain extent can be considered as mid-to long-term influences of meteorological conditions. In addition to atmospheric effects, the seasonal pattern of mortality is shaped by non-atmospheric determinants such as environmental conditions or socioeconomic status. Understanding the influence of season and other factors is essential when seeking to implement effective public health measures. The pressures of climate change make an understanding of the interdependencies between season, climate and health especially important. Methods This study investigated daily death counts collected within the Sample Vital Registration System (VSRS established by the Bangladesh Bureau of Statistics (BBS. The sample was stratified by location (urban vs. rural, gender and socioeconomic status. Furthermore, seasonality was analyzed for all-cause mortality, and several cause-specific mortalities. Daily deviation from average mortality was calculated and seasonal fluctuations were elaborated using non parametric spline smoothing. A seasonality index for each year of life was calculated in order to assess the age-dependency of seasonal effects. Results We found distinctive seasonal variations of mortality with generally higher levels during the cold season. To some extent, a rudimentary secondary summer maximum could be observed. The degree and shape of seasonality changed with the cause of death as well as with location, gender, and SES and was strongly age-dependent. Urban areas were seen to be facing an increased summer mortality peak, particularly in terms of cardiovascular mortality. Generally, children and the elderly faced stronger seasonal effects than youths and young adults. Conclusion This study clearly demonstrated the complex and dynamic nature of seasonal impacts on mortality. The modifying effect of spatial and population characteristics were highlighted. While tropical regions have

  11. Remote sensing with laser spectrum radar

    Science.gov (United States)

    Wang, Tianhe; Zhou, Tao; Jia, Xiaodong

    2016-10-01

    The unmanned airborne (UAV) laser spectrum radar has played a leading role in remote sensing because the transmitter and the receiver are together at laser spectrum radar. The advantages of the integrated transceiver laser spectrum radar is that it can be used in the oil and gas pipeline leak detection patrol line which needs the non-contact reflective detection. The UAV laser spectrum radar can patrol the line and specially detect the swept the area are now in no man's land because most of the oil and gas pipelines are in no man's land. It can save labor costs compared to the manned aircraft and ensure the safety of the pilots. The UAV laser spectrum radar can be also applied in the post disaster relief which detects the gas composition before the firefighters entering the scene of the rescue.

  12. Decision Analysis of Dynamic Spectrum Access Rules

    Energy Technology Data Exchange (ETDEWEB)

    Juan D. Deaton; Luiz A. DaSilva; Christian Wernz

    2011-12-01

    A current trend in spectrum regulation is to incorporate spectrum sharing through the design of spectrum access rules that support Dynamic Spectrum Access (DSA). This paper develops a decision-theoretic framework for regulators to assess the impacts of different decision rules on both primary and secondary operators. We analyze access rules based on sensing and exclusion areas, which in practice can be enforced through geolocation databases. Our results show that receiver-only sensing provides insufficient protection for primary and co-existing secondary users and overall low social welfare. On the other hand, using sensing information between the transmitter and receiver of a communication link, provides dramatic increases in system performance. The performance of using these link end points is relatively close to that of using many cooperative sensing nodes associated to the same access point and large link exclusion areas. These results are useful to regulators and network developers in understanding in developing rules for future DSA regulation.

  13. Low-to-moderate temperature geothermal resource assessment for Nevada: Area specific studies, final report for the period June 1, 1980-August 30, 1981

    Energy Technology Data Exchange (ETDEWEB)

    Trexler, Dennis T.; Koeing, Brian A.; Flynn, Thomas; Bruce, James L.; Ghusn, George Jr.

    1981-08-30

    The Hawthorne study area is located in Mineral County, Nevada and surrounds the municipality of the same name. It encompasses an area of approximately 310 sq. km (120 sq. mi), and most of the land belongs to the US Army Ammunition Plant. The energy needs of the military combined with those of the area population (over 5,000 residents) are substantial. The area is classified as having a high potential for direct applications using the evaluation scheme described in Trexler and others (1979). A variety of scientific techniques was employed during area-wide resource assessment. General geologic studies demonstrate the lithologic diversity in the area; these studies also indicate possible sources for dissolved fluid constituents. Geophysical investigations include aeromagnetic and gravity surveys which aid in defining the nature of regional, and to a lesser extent, local variations in subsurface configurations. Surface and near-surface structural features are determined using various types of photo imagery including low sun-angle photography. An extensive shallow depth temperature probe survey indicates two zones of elevated temperature on opposite sides of the Walker Lake basin. Temperature-depth profiles from several wells in the study area indicate significant thermal fluid-bearing aquifers. Fluid chemical studies suggest a wide spatial distribution for the resource, and also suggest a meteoric recharge source in the Wassuk Range. Finally, a soil-mercury survey was not a useful technique in this study area. Two test holes were drilled to conclude the area resource assessment, and thermal fluids were encountered in both wells. The western well has measured temperatures as high as 90 C (194 F) within 150 meters (500 ft) of the surface. Temperature profiles in this well indicate a negative temperature gradient below 180 meters (590 ft). The eastern hole had a bottom hole temperature of 61 C (142 F) at a depth of only 120 meters (395 ft). A positive gradient is observed

  14. [Simulation of image multi-spectrum using field measured endmember spectrum].

    Science.gov (United States)

    Zhang, Ting; Ding, Jian-li; Wang, Fei

    2010-11-01

    The characteristic of landscape spectrum is the basic of application of remote sensing and plays an important role in quantitative analysis of remote sensing. However, in spectrum-based application of remote sensing, because the difference of measuring scale and instrument resolution yield serious error in spectral curve and reflectance for the same landscape, there exists difficulty in quantitative retrieval of special information extraction of remote sensing. Firstly, the imaging simulation principles of the optics image was described and proposed A method using field measured endmember spectrum with higher spectrum resolutions to simulate spectrum of Multi-spectrum images with lower spectrum resolution was proposed. In the present paper, the authors take the delta oasis of Weigan and Kuqa rivers ocated in the North of Tarim Basin as study area, and choose vegetation and soil as study object. At first, we accomplished the simulation from field measured endmember for multi-spectrum by using the spectral response function of AVNIR-2, and found the large correlation between simulated multi-spectrum and pixel spectrum of AVNIR-2 by using the statistical analyse. Finally, the authors set up the linear model to accomplish the quantitative transformation from edmember scale to pixel scale. The result of this study has the realistic meaning for the quantitative application of remote sensing.

  15. Low-to-moderate temperature geothermal resource assessment for Nevada, area specific studies. Final report, June 1, 1980-August 30, 1981

    Energy Technology Data Exchange (ETDEWEB)

    Trexler, D.T.; Koenig, B.A.; Flynn, T.; Bruce, J.L.; Ghusn, G. Jr.

    1981-01-01

    The Hawthorne study area is located in Mineral County, Nevada and surrounds the municipality of the same name. It encompasses an area of approximately 310 sq. km (120 sq. mi), and most of the land belongs to the US Army Ammunition Plant. The energy needs of the military combined with those of the area population (over 5,000 residents) are substantial. The area is classified as having a high potential for direct applications using the evaluation scheme described in Texler and others (1979). A variety of scientific techniques was employed during area-wide resource assessment. General geologic studies demonstrate the lithologic diversity in the area; these studies also indicate possible sources for dissolved fluid constituents. Geophysical investigations include aero-magnetic and gravity surveys which aid in defining the nature of regional, and to a lesser extent, local variations in subsurface configurations. Surface and near-surface structural features are determined using various types of photo imagery including low sun-angle photography. An extensive shallow depth temperature probe survey indicates two zones of elevated temperature on opposite sides of the Walker Lake basin. Temperature-depth profiles from several wells in the study area indicate significant thermal fluid-bearing aquifers. Fluid chemical studies suggest a wide spatial distribution for the resource, and also suggest a meteoric recharge source in the Wassuk Range. Finally, a soil-mercury survey was not a useful technique in this study area. Two test holes were drilled to conclude the area resource assessment, and thermal fluids were encountered in both wells. The western well has measured temperatures as high as 90 C (194 F) within 150 meters (500 ft) of the surface. Temperature profiles in this well indicate a negative temperature gradient below 180 meters (590 ft). The eastern hole had a bottom hole temperature of 61 C (142 F) at a depth of only 120 meters (395 ft). A positive gradient is observed

  16. Autism Spectrum Disorder (ASD)

    Science.gov (United States)

    ... Español (Spanish) Recommend on Facebook Tweet Share Compartir Autism spectrum disorder (ASD) is a developmental disability that can cause ... factors that may put children at risk for autism spectrum disorder (ASD) and other developmental disabilities. More E-mail ...

  17. The CMBR spectrum

    Energy Technology Data Exchange (ETDEWEB)

    Stebbins, A.

    1997-05-01

    Here we give an introduction to the observed spectrum of the Cosmic Microwave Background Radiation (CMBR) and discuss what can be learned about it. Particular attention will be given to how Compton scattering can distort the spectrum of the CMBR. An incomplete bibliography of relevant papers is also provided.

  18. Fetal Alcohol Spectrum Disorder

    Science.gov (United States)

    Caley, Linda M.; Kramer, Charlotte; Robinson, Luther K.

    2005-01-01

    Fetal alcohol spectrum disorder (FASD) is a serious and widespread problem in this country. Positioned within the community with links to children, families, and healthcare systems, school nurses are a critical element in the prevention and treatment of those affected by fetal alcohol spectrum disorder. Although most school nurses are familiar…

  19. Injection of Retrograde Beads into the Nucleus Accumbens (NAc) and Medial Prefronral Cortex (mPFC) to Isolate Projection-Specific Neurons in the Ventral Tegmental Area (VTA)

    OpenAIRE

    sprotocols

    2015-01-01

    Authors: Jessica Walsh, Allyson Friedman, Dipesh Chaudhury, Barbara Juarez, Stacy Ku & Ming-Hu Han ### Abstract Retrograde dyes, such as lumafluors, have been used as tracers to visualize neurons that project to a specific target region. Injection of these dyes provides an important method in being able to understand the functional role of projection-specific neurons. Lumafluors can be directly injected into a target brain region of a mouse and dye positive cells from the project...

  20. Wave Reflection Coefficient Spectrum

    Institute of Scientific and Technical Information of China (English)

    俞聿修; 邵利民; 柳淑学

    2003-01-01

    The wave reflection coefficient frequency spectrum and directional spectrum for concrete face slope breakwaters and rubble mound breakwaters are investigated through physical model tests in the present study. The reflection coefficients of oblique irregular waves are analyzed by the Modified Two-Point Method (MTPM) proposed by the authors. The results show that the wave reflection coefficient decreases with increasing wave frequency and incident angle or decreasing structure slope. The reflection coefficient frequency spectrum and its variation with Iribarren number are given in this paper. The paper also suggests an empirical 3-dimensional reflection coefficient spectrum, i.e. reflection coefficient directional spectrum, which can be used to illustrate quantitatively the variation of reflection coefficient with the incident angle and the Iribarren number for oblique irregular waves.

  1. A COMPARATIVE EPIDEMIOLOGIC STUDY OF SPECIFIC ANTIBODIES (IgM AND IgA AND PARASITOLOGICAL FINDINGS IN AN ENDEMIC AREA OF LOW TRANSMISSION OF Schistosoma mansoni

    Directory of Open Access Journals (Sweden)

    KANAMURA Herminia Yohko

    1998-01-01

    Full Text Available The diagnostic potential of circulating IgM and IgA antibodies against Schistosoma mansoni gut-associated antigens detected by the immunofluorescence test (IFT on adult worm paraffin sections was evaluated comparatively to the fecal parasitological method, for epidemiological purposes in low endemic areas for schistosomiasis. Blood samples were collected on filter paper from two groups of schoolchildren living in two different localities of the municipality of Itariri (São Paulo, Brazil with different histories and prevalences of schistosomiasis. The parasitological and serological data were compared to those obtained for another group of schoolchildren from a non-endemic area for schistosomiasis. The results showed poor sensitivity of the parasitological method in detecting individuals with low worm burden and indicate the potential of the serological method as an important tool to be incorporated into schistosomiasis control and vigilance programs for determining the real situation of schistosomiasis in low endemic areas.

  2. Mutation Spectrum of β-Thalassemia and Other Hemoglobinopathies in Chittagong, Southeast Bangladesh.

    Science.gov (United States)

    Chatterjee, Tridip; Chakravarty, Amit; Chakravarty, Sudipa; Chowdhury, Mahmood Ahmed; Sultana, Razia

    2015-01-01

    Thalassemia is one of the most common autosomal recessive blood disorders in the world. It shows a variety of clinical expression, starting from asymptomatic to severe blood transfusion dependence. More than 500 alleles have been characterized in or around the β-globin region. Moreover, most geographical regions have their own characteristics, frequency and availability of these alleles, predominantly circulating within the communities present in that particular region. In this study, we explored the spectrum of β-thalassemia (β-thal) alleles present in Chittagong, Southeast Bangladesh. This study comprises β-thal and Hb E (HBB: c.79 G > A) patients from in and around the area of Chittagong. Not only exploring the complete β-globin mutation spectrum of the area, but we also tried to look at the origin of the mutated alleles. The β-thal mutations of Bangladesh show a relatively wide spectrum of alleles, which further demonstrates the heterogeneity of the disease in this country. Although our study showed that the majority of the mutations have their origin in neighboring countries such as India, countries of Southeast Asia, Pakistan, etc., some unusual alleles do not originate in neighboring countries and put a little more diversity in the overall spectrum of β-thal-specific alleles. Overall, this study demonstrates the mutation spectrum related to β-thal in Chittagong, Southeast Bangladesh.

  3. Low density parasitaemia, red blood cell polymorphisms and Plasmodium falciparum specific immune responses in a low endemic area in northern Tanzania

    DEFF Research Database (Denmark)

    Shekalaghe, Seif; Alifrangis, Michael; Mwanziva, Charles;

    2009-01-01

    BACKGROUND: Low density Plasmodium falciparum infections, below the microscopic detection limit, may play an important role in maintaining malaria transmission in low endemic areas as well as contribute to the maintenance of acquired immunity. Little is known about factors influencing the occurre...

  4. Metals and Rare Earth Elements in polar aerosol as specific markers of natural and anthropogenic aerosol sources areas and atmospheric transport processes

    Science.gov (United States)

    Giardi, Fabio; Becagli, Silvia; Caiazzo, Laura; Cappelletti, David; Grotti, Marco; Malandrino, Mery; Salzano, Roberto; Severi, Mirko; Traversi, Rita; Udisti, Roberto

    2016-04-01

    Metals and Rare Earth Elements (REEs) in the aerosol have conservative properties from the formation to the deposition and can be useful to identify and quantify their natural and anthropic sources and to study the atmospheric transport processes. In spite of their importance relatively little is known about metals and especially REEs in the Artic atmosphere due to their low concentration in such environment. The present work reports the first attempt to determine and interpret the behaviour of metals and REEs in polar aerosol at high temporal resolution. Daily PM10 samples of arctic atmospheric particulate were collected on Teflon filters, during six spring-summer campaigns, since 2010, in the laboratory of Gruvebadet in Ny Ålesund (78°56' N, 11°56' E, Svalbard Islands, Norway). Chemical analyses were carried out through Inductively Coupled Plasma Mass Spectrometer provided with a desolvation nebulizer inlet system, allowing to reduce isobaric interferences and thus to quantify trace and ultra-trace metals in very low concentration in the Arctic aerosol samples. The results are useful in order to study sources areas, transport processes and depositional effects of natural and anthropic atmospheric particulate reaching the Arctic from southern industrialized areas; moreover, the observed seasonal trends give information about the different impact of natural and anthropic emissions driven by phenomena such as the Arctic Haze and the melting of the snow. In particular Rare Earth Elements (often in the ppt range) can be considered as soil's fingerprints of the particulate source areas and their determination, together with air-mass backtrajectory analysis, allow to identify dust source areas for the arctic mineral aerosol.

  5. Detection of filaria-specific IgG4 antibodies using Brugia Rapid test in individuals from an area highly endemic for Brugia timori.

    Science.gov (United States)

    Supali, T; Rahmah, N; Djuardi, Y; Sartono, E; Rückert, Paul; Fischer, P

    2004-05-01

    The filarial parasite Brugia timori is of great public health importance in some islands of Eastern Indonesia. To establish a simple serological test for the identification and post-treatment monitoring of areas endemic for B. timori, a rapid immunochromatographic dipstick test (Brugia Rapid, BR) was evaluated on microfilaraemic and amicrofilaraemic individuals. This test is based on the detection of anti-filarial IgG4 antibodies that react with a recombinant Brugia malayi antigen (BmR1). In our study area on Alor island the prevalence of microfilaraemia was 26%. With the BR test, 100% of 196 sera from microfilaraemic persons and 76% of 563 sera from amicrofilaraemic persons, either symptomatic or asymptomatic, reacted positive. All 50 control sera from areas non-endemic for lymphatic filariasis gave negative BR test results. This study showed that the BR test can be also used to detect antibodies against B. timori. Due to the high prevalence of IgG4 antibodies as detected by the BR test (81%), no significant correlation with the prevalence of microfilaraemia could be detected within the endemic village. The BR test also shows great promise to be employed as a monitoring tool for B. timori in the framework of the Global Program to Eliminate Lymphatic Filariasis (GPELF).

  6. The marine diversity spectrum

    DEFF Research Database (Denmark)

    Reuman, Daniel C.; Gislason, Henrik; Barnes, Carolyn

    2014-01-01

    of taxonomy (all the species in a region regardless of clade) are much less studied but are equally important and will illuminate a different set of ecological and evolutionary processes. We develop and test a mechanistic model of how diversity varies with body mass in marine ecosystems. The model predicts...... the form of the diversity spectrum', which quantifies the distribution of species' asymptotic body masses, is a species analogue of the classic size spectrum of individuals, and which we have found to be a new and widely applicable description of diversity patterns. The marine diversity spectrum...... is predicted to be approximately linear across an asymptotic mass range spanning seven orders of magnitude. Slope -0 center dot 5 is predicted for the global marine diversity spectrum for all combined pelagic zones of continental shelf seas, and slopes for large regions are predicted to lie between -0 center...

  7. Fast Spectrum Reactors

    CERN Document Server

    Todd, Donald; Tsvetkov, Pavel

    2012-01-01

    Fast Spectrum Reactors presents a detailed overview of world-wide technology contributing to the development of fast spectrum reactors. With a unique focus on the capabilities of fast spectrum reactors to address nuclear waste transmutation issues, in addition to the well-known capabilities of breeding new fuel, this volume describes how fast spectrum reactors contribute to the wide application of nuclear power systems to serve the global nuclear renaissance while minimizing nuclear proliferation concerns. Readers will find an introduction to the sustainable development of nuclear energy and the role of fast reactors, in addition to an economic analysis of nuclear reactors. A section devoted to neutronics offers the current trends in nuclear design, such as performance parameters and the optimization of advanced power systems. The latest findings on fuel management, partitioning and transmutation include the physics, efficiency and strategies of transmutation, homogeneous and heterogeneous recycling, in addit...

  8. Possible role of specific immunoglobulin M antibodies to Plasmodium falciparum antigens in immunoprotection of humans living in a hyperendemic area, Burkina Faso

    DEFF Research Database (Denmark)

    Boudin, C; Chumpitazi, B; Dziegiel, Morten Hanefeld

    1993-01-01

    of antibodies to crude extracts of Plasmodium falciparum (IgG or IgM antisomatic and IgG antiexoantigens) were tested by IFI or enzyme-linked immunosorbent assay and were followed up according to the fluctuations of the parasite densities. Specific IgG antibodies had the same evolution as parasite densities....... By contrast, specific IgM antibodies increased when IgG and parasite densities began to decrease (despite a high inoculation rate). A longitudinal survey of 77 children and adults was conducted in another village (Dafinso). In that study, clinical follow-up of the selected individuals allowed us to define...... three groups in the population. Children in group 1 were considered nonimmune (children with one or more malaria attacks). Group 2 was composed of semiimmune children who did not present with any malarial attack during the survey but who had high levels of parasitemia during the transmission period...

  9. Spectrum and network measurements

    CERN Document Server

    Witte, Robert A

    2014-01-01

    This new edition of Spectrum and Network Measurements enables readers to understand the basic theory, relate it to measured results, and apply it when creating new designs. This comprehensive treatment of frequency domain measurements successfully consolidates all the pertinent theory into one text. It covers the theory and practice of spectrum and network measurements in electronic systems. It also provides thorough coverage of Fourier analysis, transmission lines, intermodulation distortion, signal-to-noise ratio and S-parameters.

  10. Low- to moderate-temperature geothermal resource assessment for Nevada: area specific studies, Pumpernickel Valley, Carlin and Moana. Final report June 1, 1981-July 31, 1982

    Energy Technology Data Exchange (ETDEWEB)

    Trexler, D.T.; Flynn, T.; Koenig, B.A.; Bell, E.J.; Ghusn, G. Jr.

    1982-01-01

    Geological, geophysical and geochemical surveys were used in conjunction with temperature gradient hole drilling to assess the geothermal resources in Pumpernickel Valley and Carlin, Nevada. This program is based on a statewide assessment of geothermal resources that was completed in 1979. The exploration techniques are based on previous federally-funded assessment programs that were completed in six other areas in Nevada and include: literature search and compilation of existing data, geologic reconnaissance, chemical sampling of thermal and non-thermal fluids, interpretation of satellite imagery, interpretation of low-sun angle aerial photographs, two-meter depth temperature probe survey, gravity survey, seismic survey, soil-mercury survey, and temperature gradient drilling.

  11. Gene-specific disruption of endocannabinoid receptor 1 (cnr1a) by ethanol probably leads to the development of fetal alcohol spectrum disorder (FASD) phenotypes in Japanese rice fish (Oryzias latipes) embryogenesis.

    Science.gov (United States)

    Dasmahapatra, Asok K; Khan, Ikhlas A

    2015-01-01

    The present study was designed to investigate the probable roles played by cannabinoid (CB) receptors in fetal alcohol spectrum disorder (FASD) induction in Japanese rice fish (Oryzias latipes). Searching of public databases (GenBank, Ensembl) indicated that the Japanese rice fish genome includes three human ortholog CB receptor genes (cnr1a, cnr1b and cnr2). Quantitative real-time PCR (qPCR) and whole mount in situ hybridization (WMISH) techniques were used to analyze the expression of these cnr genes during Japanese rice fish embryogenesis and also in response to developmental ethanol exposure. qPCR analyses showed that the expression of all three CB receptor genes were developmentally regulated and only cnr2 showed maternal expression. The mRNA concentrations of these genes were found to be enhanced after 3 dpf and attained maximal levels either prior to or after hatching. WMISH technique indicated that all three cnr genes were expressed in the head region of hatchlings. During development, ethanol selectively attenuated the expression of cnr1a mRNA only. Blocking of cnr1a mRNA by CB1 receptor antagonists rimonabant (10-20 μM) or AM251 (0.2-1 μM) 0-2 dpf were unable to induce any FASD-related phenotypic features in embryos or in hatchlings. However, continuous exposure of the embryos (0-6 dpf) to AM251 (1 μM) was able to reduce the hatching efficiency of the embryos. Our data indicated that in Japanese rice fish, ethanol disrupted the expression of only cnr1a in a concentration-dependent manner that induced delay in hatching and might be responsible for the development of FASD phenotypes.

  12. Plantaris muscle weakness in old mice: relative contributions of changes in specific force, muscle mass, myofiber cross-sectional area, and number.

    Science.gov (United States)

    Ballak, Sam B; Degens, Hans; Busé-Pot, Tinelies; de Haan, Arnold; Jaspers, Richard T

    2014-01-01

    The age-related decline in muscle function contributes to the movement limitations in daily life in old age. The age-related loss in muscle force is attributable to loss of myofibers, myofiber atrophy, and a reduction in specific force. The contribution of each of these determinants to muscle weakness in old age is, however, largely unknown. The objective of this study is to determine whether a loss in myofiber number, myofiber atrophy, and a reduction in specific muscle force contribute to the age-related loss of muscle force in 25-month-old mouse. Maximal isometric force of in situ m. plantaris of C57BL/6J male adult (9 months) and old (25 months) mice was determined and related to myofiber number, myofiber size, intramuscular connective tissue content, and proportion of denervated myofibers. Isometric maximal plantaris muscle force was 13 % lower in old than adult mice (0.97 ± 0.05 N vs. 0.84 ± 0.03 N; P < 0.05). M. plantaris mass of old mice was not significantly smaller than that of adult mice. There was also no significant myofiber atrophy or myofiber loss. Specific muscle force of old mice was 25 % lower than that of adult mice (0.55 ± 0.05 vs. 0.41 ± 0.03 N·mm(-2), P < 0.01). In addition, with age, the proportion of type IIB myofibers decreased (43.6 vs. 38.4 %, respectively), while the connective tissue content increased (11.6 vs. 16.4 %, respectively). The age-related reduction in maximal isometric plantaris muscle force in 25-month-old male C57BL/6J mice is mainly attributable to a reduction in specific force, which is for 5 % explicable by an age-related increase in connective tissue, rather than myofiber atrophy and myofiber loss.

  13. The Use of Evidenced-Based Practices in the Provision of Social Skills Training for Students with Autism Spectrum Disorder among School Psychologists

    Science.gov (United States)

    Combes, Bertina H.; Chang, Mei; Austin, Jennifer E.; Hayes, Demarquis

    2016-01-01

    This study aimed to explore school psychologists' use of evidence-based practices (EBP), specifically in the area of social skills training, for students with an autism spectrum disorder (ASD). Participants were 220 school psychologists practicing in public school settings who provided social skills training to students with ASD. Participants were…

  14. Mapping the current situation in life and life satisfaction in specific areas of life Center for psychosocial rehabilitation clients, company MANA, ops Olomouc

    Directory of Open Access Journals (Sweden)

    Soňa Lemrová

    2014-12-01

    Full Text Available The paper is concerned with mapping the quality of life of individuals diagnosed with schizophrenia. Surveying the quality of life of schizophrenics may be complicated due to the symptomatology - e.g. negative results during the higher levels of anxiety. Apart from health: age, gender, occupation, family, social contacts, finances, opportunities for rehabilitation and psychoeducational programmes are all among the important factors of the individual quality of life. Our research group comprised 16 clients (male n=12, female n=4 of the Psychosocial Rehabilitation Centre, MANA o.p.s. Olomouc. Average age of our respondents was 38.2. Except for 4 male respondents, all the rest were unemployed at the time of the survey, 3 respondents were living alone, others with parents or a partner. Average age of the male respondents at the time of their first hospitalization was 22, of the female respondents 18.5. The Czech version of the Quality of life questionnaire (Dotazník životní spokojenosti - DŽS was the basis of our primary method. In view of the sociodemographic data of our respondents, we have surveyed the level of the individual quality of life in the areas of health, financial situation, oneself and friends, acquaintances and relatives. A supplementary method was based on the SEIQoL (Schedule for the Evaluation of Individual Quality of Life, a questionnaire for monitoring the importance of happiness with individually chosen life themes (QL and an overall level of quality of life (VAS. The goal was to ascertain the level of happiness in the aforementioned areas of life DŽS and the correlation with age, importance and quality of life themes and their correlation with current overall quality of life. The lowest level of happiness (DŽS was measured in the overall level of the current quality of life (VAS in connection to gender (male=60.7%, female=43.8%, but in view of the low number of female respondents (n=4 we consider this result an

  15. The area quantum and Snyder space

    Energy Technology Data Exchange (ETDEWEB)

    Romero, Juan M. [Instituto de Ciencias Nucleares, Universidad Nacional Autonoma de Mexico, Apartado Postal 70-543, Mexico 04510 DF (Mexico)], E-mail: sanpedro@nucleares.unam.mx; Zamora, Adolfo [Departamento de Matematicas Aplicadas y Sistemas, Universidad Autonoma Metropolitana-Cuajimalpa, Mexico 01120 DF (Mexico)], E-mail: zamora@correo.cua.uam.mx

    2008-03-13

    We show that in the Snyder space the area of the disc and of the sphere can be quantized. It is also shown that the area spectrum of the sphere can be related to the Bekenstein conjecture for the area spectrum of a black hole horizon.

  16. Preparation of activate carbon with high specific surface area from beer lees by chemical activation with KOH; Suisankakariumu wo mochiita yakuhin fukatsuho ni yoru birukasu karano kohihyoumenseki kasseitan no seizo

    Energy Technology Data Exchange (ETDEWEB)

    Hayashi, J.; Kubo, A.; Furukawa, A.; Muroyama, K. [Kansai University, Osaka (Japan). Dept. of Chemical Engineering

    2000-03-10

    Activated carbons with high specific surface area were prepared from beer lees by chemical activation with KOH. We examined the influence of the preparation conditions, such as temperature and impregnation ratio, on the pore structure of the prepared activated carbon. The specific surface area increased with an increase in carbonization temperature up to 800 degree C and decreased at 900 degree C because of excess activation. It reached a maximum value at the impregnation ratio of 2.0. The activated carbon, which was prepared at the carbonization temperature of 800 degree C and at the impregnation ratio of 2.0, had very high specific surface area of 2,440 m{sup 2}/g. It was found that KOH worked effectively as the activating reagent in two temperature ranges, below 500 degree C and above 600 degree C. The amount of benzene and acetone adsorbed on the prepared activated carbon were much larger than that on the commercial activated carbons. (author)

  17. Genetic Testing for Autism Spectrum Disorders

    Science.gov (United States)

    Bauer, Sarah C.; Msall, Michael E.

    2011-01-01

    Children with autism spectrum disorders (ASD) have unique developmental and behavioral phenotypes, and they have specific challenges with communication, social skills, and repetitive behaviors. At this time, no single etiology for ASD has been identified. However, evidence from family studies and linkage analyses suggests that genetic factors play…

  18. IR Spectrum Data Bank System

    Institute of Scientific and Technical Information of China (English)

    Xie Dilin

    2004-01-01

    The infrared spectra of pure compounds of ninety thousands, poly compounds of twelve thousand, drugs of one thousand were included in the data bank. All of them can be searched out according to their serial number, chemical name, commercial name, amount of each atoms, or molecular formula, as well as their spectrum peak appearances. Program for spectrum information inputting, program for spectrum information search and program for spectrum peak appearance search were included in the system; in addition, spectrum information data bank, spectrum peak code data bank and spectrum figure data bank were attached to the system. System program was written by Visial Basic, and run under Windows system. The spectrum information data bank and spectrum figure data bank were administrated by Microsoft Access.The program for spectrum message inputting can be used to add message data and spectrum figure of some new compounds into the data banks by users themselves. The program for spectrum message search was designed to find out all the message data and spectrum figure of interested compound according to someone of the message data. The program for spectrum peak search was designed to find out some spectra most similar in peak shape with unknown spectrum by peak to peak comparison. When the wavenumbers and transmittances of main peaks in the spectrum of unknown sample were entered, the spectrum peak search was performed and several hits with higher similarity were reported including their similarity scores, spectrum serial numbers, sample's states,melt points, molecular formulas as well as spectrum images. If the search result was not satisfactory,some methods to modify spectrum parameters were reminded and search was performed again.

  19. Compound Specific Radiocarbon Analysis (CSRA) Of Polycyclic Aromatic Hydrocarbons(PAHs) in Fine Organic Aerosols From Residential Area Of Suburb Tokyo

    Science.gov (United States)

    Kumata, H.; Uchida, M.; Sakuma, E.; Fujiwara, K.; Yoneda, M.; Shibata, Y.

    2005-12-01

    Atmospheric polycyclic aromatic hydrocarbons (PAHs) originate mostly from incomplete combustion of carbon-based fuels. Amongst atmospheric contaminants, PAHs account for most (35-82 percent) of the total mutagenic activity of ambient aerosols. Hence, reduction of air pollution by PAHs is essential for an effective air quality control, which requires reliable source apportionment. Recently developed preparative capillary GC system and microscale 14C analysis made CSRA applicable to environmental samples. The 5730 yr half-life of 14C makes it an ideal tracer for identifying combustion products derived from fossil fuels (14C-free) vs. those from modern biomass (contemporary 14C). In the present study we performed radiocarbon analysis of PAHs in fine particulate aerosols (PM10 and PM1.1) from a residential area in suburb Tokyo, to apportion their origin between fossil and biomass combustion. Acquisition of source information for size segregated aerosols (i.e., PM1.1) from 14C measurement was of special interest as particles with diameter of 1μm or less are known to be able to remain suspended in air for weeks and penetrate into the deepest part of the respiratory system. Total PAHs concentrations (sum of 38 compounds with 3-6 aromatic rings) ranged 0.94-3.25 ng/m3 for PM10 and 0.69-2.68 ng/m3 for PM1.1 samples. Observation of relatively small amount of retene (0.2-0.4 percent of total PAHs) indicates some contribution from wood (Gymnosperm) combustion. Diagnostic isomer pair ratios of PAHs (i.e., 1,7-/2,6-dimethylphenanthrene, fluoranthene/pyrene and indeno [1,2,3-cd]pyrene/benzo[ghi]perylene) indicated mixed contributions both from petroleum and wood/coal combustion sources. Also the ratios implied that the latter source become relatively important in winter than the rest of the year for both PM10 and PM1.1 samples, which coincides with seasonal trend of retene proportion. The source information obtained from 14C analyses will be compared and discussed against that

  20. The comorbidity of ADHD and autism spectrum disorder.

    Science.gov (United States)

    Antshel, Kevin M; Zhang-James, Yanli; Faraone, Stephen V

    2013-10-01

    ADHD and autism spectrum disorder are common psychiatric comorbidities to each another. In addition, there is behavioral, biological and neuropsychological overlap between the two disorders. There are also several important differences between autism spectrum disorder and ADHD. Treatment strategies for the comorbid condition will also be reviewed. Future areas of research and clinical need will be discussed.

  1. Otopalatodigital spectrum disorders: refinement of the phenotypic and mutational spectrum.

    Science.gov (United States)

    Moutton, Sébastien; Fergelot, Patricia; Naudion, Sophie; Cordier, Marie-Pierre; Solé, Guilhem; Guerineau, Elodie; Hubert, Christophe; Rooryck, Caroline; Vuillaume, Marie-Laure; Houcinat, Nada; Deforges, Julie; Bouron, Julie; Devès, Sylvie; Le Merrer, Martine; David, Albert; Geneviève, David; Giuliano, Fabienne; Journel, Hubert; Megarbane, André; Faivre, Laurence; Chassaing, Nicolas; Francannet, Christine; Sarrazin, Elisabeth; Stattin, Eva-Lena; Vigneron, Jacqueline; Leclair, Danielle; Abadie, Caroline; Sarda, Pierre; Baumann, Clarisse; Delrue, Marie-Ange; Arveiler, Benoit; Lacombe, Didier; Goizet, Cyril; Coupry, Isabelle

    2016-08-01

    Otopalatodigital spectrum disorders (OPDSD) constitute a group of dominant X-linked osteochondrodysplasias including four syndromes: otopalatodigital syndromes type 1 and type 2 (OPD1 and OPD2), frontometaphyseal dysplasia, and Melnick-Needles syndrome. These syndromes variably associate specific facial and extremities features, hearing loss, cleft palate, skeletal dysplasia and several malformations, and show important clinical overlap over the different entities. FLNA gain-of-function mutations were identified in these conditions. FLNA encodes filamin A, a scaffolding actin-binding protein. Here, we report phenotypic descriptions and molecular results of FLNA analysis in a large series of 27 probands hypothesized to be affected by OPDSD. We identified 11 different missense mutations in 15 unrelated probands (n=15/27, 56%), of which seven were novel, including one of unknown significance. Segregation analyses within families made possible investigating 20 additional relatives carrying a mutation. This series allows refining the phenotypic and mutational spectrum of FLNA mutations causing OPDSD, and providing suggestions to avoid the overdiagnosis of OPD1.

  2. Inf rared Spectrum Analysis of Propolis and Tree Gum Collected f rom Different Areas%不同地区蜂胶和树胶的红外谱图分析

    Institute of Scientific and Technical Information of China (English)

    罗火林; 刘星星; 龚上佶; 郭夏丽; 罗丽萍

    2015-01-01

    蜂胶有抗菌、抗病毒、保肝、抗癌等功效,被誉为“紫色黄金”,而当前蜂胶市场制假掺假现象愈演愈烈。为快速鉴别蜂胶的真假与优劣,以41种中国蜂胶、一种美国蜂胶和两种树胶为实验材料,利用傅里叶变换红外光谱仪采集其红外谱图,以青海蜂胶为参照样品分析相似度,并利用主成分分析法进行数据解读。结果表明,所有蜂胶在2848.53~2849.08和2916.76~2917.74 cm-1两个区域都存在特征峰,而树胶在这两个区域内无特征峰。树胶的特征峰区域为1150~1300和1550~1650 cm-1。通过这些差异可以快速甄别蜂胶和树胶,鉴别真假蜂胶。以具有较高品质的青海蜂胶为参照物,匹配性分析显示,树胶与蜂胶完全不匹配,而42种蜂胶样品均与青海蜂胶有较高的匹配度(>80%),PCA结果显示,蜂胶和树胶,以及不同气候带、不同颜色的蜂胶可以较好区分开来。本研究首次基于红外光谱技术对不同蜂胶进行分析,有望建立蜂胶真假及优劣鉴定的新方法。%Propolis possesses functions of antibacterial ,antiviral ,anticancer ,and liver protection ,and is known as the“purple gold” ,however ,the phenomenon which making and selling of counterfeit are growing in intensity .In order to establish a au‐thenticity and quality of propolis evaluation model ,in this paper ,forty‐one Chinese propolis ,one proplis from United States and two tree gums were used for experimental materials .The infrared spectrum collection was performed by Fourier transform infra‐red spectrometer ,and principal component analysis (PCA ) was used for data analysis .The result showed that ,the infrared spectrum of propolis and tree gum were significantly different .The propolis characteristic peak only appeared in 2 500~3 500 and 400~1 800 cm -1 .All propolis had two frequency region of characteristic peaks ,2 849 .08~ 2 848.53 and 2 917.74~2 916

  3. What is a Spectrum?

    CERN Document Server

    Bolton, Adam S; Brownstein, Joel; Pandey, Parul; Schlegel, David; Shu, Yiping

    2011-01-01

    This contribution describes the "spectro-perfectionism" algorithm of Bolton & Schlegel (2010, PASP, 122, 248) that is being implemented within the Baryon Oscillation Spectroscopic Survey (BOSS) of the Sloan Digital Sky Survey III (SDSS-III), in terms of its potential to deliver Poisson-limited sky subtraction and lossless compression of the input spectrum likelihood functional given raw CCD data.

  4. Autism Spectrum Disorder (ASD)

    Science.gov (United States)

    ... with: 1 Communication and interaction with other people Restricted interests and repetitive behaviors Different people with autism can have different symptoms. For this reason, autism is known as a spectrum disorder —which means that there is a range of ...

  5. Autism Spectrum Disorder

    Centers for Disease Control (CDC) Podcasts

    2014-04-02

    This podcast discusses autism spectrum disorder (ASD), a developmental disability that causes problems with social, communication, and behavioral skills. CDC estimates that one in 68 children has been identified as having ASD.  Created: 4/2/2014 by National Center on Birth Defects and Developmental Disabilities (NCBDDD).   Date Released: 4/2/2014.

  6. Battlefield spectrum management

    Science.gov (United States)

    Sivakumar, C.

    1997-06-01

    Modern tactical communications systems rely on radios to support network and user connectivity. One of the challenges for network planners and managers is to make best use of scarce and vulnerable frequency spectrum resources to support the communication needs of war fighters. With the wide variety of Iris radio types typically to be deployed in the battlefield (ranging from high frequency to super high frequency), a comprehensive suite of tools is necessary to ensure that frequency interference is kept minimum. Without a sophisticated frequency spectrum management system, the most advanced tactical communications systems could be rendered useless, jeopardizing human life and national security. For these reasons, it is important to develop an Iris wide battlefield spectrum management capability that takes full advantage of current frequency spectrum management research and development (R&D), related tools, and supporting technology for assigning frequencies. This session briefly describes various assignment strategies being adopted in the Iris BFSM for overcoming cosite/collocated/farsite interferences along with the propagation models [from high frequency (HF) to super high frequency (SHF)] used for the assignment of frequencies. Also a brief thread outlining the process for generating frequency allocation/assignment request and analysis of frequency interference is discussed.

  7. Sinclair ZX Spectrum.

    Science.gov (United States)

    Rodwell, Peter

    1982-01-01

    Describes and evaluates the hardware, software, peripheral devices, performance capabilities, and programing capacity of the Sinclair ZX Spectrum microcomputer. The computer's display system, its version of the BASIC programing language, its graphics capabilities, and the unique features of its data entry keyboard are discussed. (JL)

  8. Psychometric analysis of the Systematic Observation of Red Flags for autism spectrum disorder in toddlers.

    Science.gov (United States)

    Dow, Deanna; Guthrie, Whitney; Stronach, Sheri T; Wetherby, Amy M

    2017-04-01

    The purpose of this study was to examine the utility of the Systematic Observation of Red Flags as an observational level-two screening measure to detect risk for autism spectrum disorder in toddlers when used with a video-recorded administration of the Communication and Symbolic Behavior Scales. Psychometric properties of the Systematic Observation of Red Flags were examined in a sample of 247 toddlers of 16- to 24 months old: 130 with autism spectrum disorder, 61 with developmental delays, and 56 typically developing. Individual items were examined for performance to create an algorithm with improved sensitivity and specificity, yielding a total Composite score and Domain scores for Social Communication and Restricted Repetitive Behaviors. Codes indicating clear symptom presence were collapsed to yield a count of the number of Red Flags for the overall scale and each symptom domain. Results indicated significant group differences with large effects for the Composite, both Domain scores, and Red Flags score, and good discrimination (area under the curve = 0.84-0.87) between autism spectrum disorder and nonspectrum groups for the Composite, Social Communication Domain, and Social Communication Red Flags score. The Systematic Observation of Red Flags provides an observational screening measure for 16- to 24-month-olds with good discrimination, sensitivity, and specificity. A cutoff of 20 on the Composite is recommended to optimally detect autism spectrum disorder risk.

  9. Cultural Basis of Social "Deficits" in Autism Spectrum Disorders

    Science.gov (United States)

    Perepa, Prithvi

    2014-01-01

    There is very little research that specifically looks at how autism spectrum disorders are perceived in various communities. This qualitative research was conducted with parents who had children on the autistic spectrum belonging to four different ethnic communities (White British, Somali, West African and South Asian--63 in total) and living in…

  10. Broad-spectrum antiviral therapeutics.

    Directory of Open Access Journals (Sweden)

    Todd H Rider

    Full Text Available Currently there are relatively few antiviral therapeutics, and most which do exist are highly pathogen-specific or have other disadvantages. We have developed a new broad-spectrum antiviral approach, dubbed Double-stranded RNA (dsRNA Activated Caspase Oligomerizer (DRACO that selectively induces apoptosis in cells containing viral dsRNA, rapidly killing infected cells without harming uninfected cells. We have created DRACOs and shown that they are nontoxic in 11 mammalian cell types and effective against 15 different viruses, including dengue flavivirus, Amapari and Tacaribe arenaviruses, Guama bunyavirus, and H1N1 influenza. We have also demonstrated that DRACOs can rescue mice challenged with H1N1 influenza. DRACOs have the potential to be effective therapeutics or prophylactics for numerous clinical and priority viruses, due to the broad-spectrum sensitivity of the dsRNA detection domain, the potent activity of the apoptosis induction domain, and the novel direct linkage between the two which viruses have never encountered.

  11. 历史文化街区的市政工程技术规范瓶颈与对策%BOTTLENECK AND STRATEGY OF MUNICIPAL ENGINEERING SPECIFICATION IN HISTORIC CONSERVATION AREA

    Institute of Scientific and Technical Information of China (English)

    李新建; 朱光亚

    2012-01-01

    我国历史文化街区缺乏专门的市政工程技术规范,保护规划实践往往因套用现行一般市政工程技术规范而导致偏差.通过分析我国现行市政工程技术规范和标准以“指令性”的具体技术手段和参数为主、适应性和灵活性不足的缺陷,指出历史文化街区应制定适应其物质空间特性和遗产保护要求的专门的“性能化”市政工程技术规范,与一般城市建设标准保持“适度差异”,并提出实现这一目标的法规和管理对策.%In China,historic conservation area has not pertinent technique specification for its municipal engineering, and its conservation is always harmed by mechanical application of existing generic specification of urban construction, which is prescriptive-based and inadaptable to heritage conservation. Municipal engineering in historic conservation area needs special performance-based technique specification, which is allowably different from those generic standards and requires some legislative and administrant measures to put in practice.

  12. Association of Schizophrenia Spectrum and Autism Spectrum Disorder (ASD) Symptoms in Children with ASD and Clinic Controls

    Science.gov (United States)

    Gadow, Kenneth D.

    2013-01-01

    Objective: This study examines relations between the severity of specific symptoms of schizophrenia spectrum disorder (SSD) and severity of the three defining symptom domains of autism spectrum disorder (ASD) in children with ASD (N = 147) and child psychiatry outpatient referrals (Controls; N = 339). Method: Participants were subdivided into four…

  13. Raman spectrum of asphaltene

    KAUST Repository

    Abdallah, Wael A.

    2012-11-05

    Asphaltenes extracted from seven different crude oils representing different geological formations from around the globe were analyzed using the Raman spectroscopic technique. Each spectrum is fitted with four main peaks using the Gaussian function. On the basis of D1 and G bands of the Raman spectrum, asphaltene indicated an ordered structure with the presence of boundary defected edges. The average aromatic sheet size of the asphaltene molecules is estimated within the range of 1.52-1.88 nm, which represents approximately seven to eight aromatic fused rings. This estimation is based on the integrated intensity of D1 and G bands, as proposed by Tunistra and Koenig. The results here are in perfect agreement with so many other used techniques and indicate the potential applicability of Raman measurements to determine the average aromatic ring size and its boundary. © 2012 American Chemical Society.

  14. Spread spectrum image steganography.

    Science.gov (United States)

    Marvel, L M; Boncelet, C R; Retter, C T

    1999-01-01

    In this paper, we present a new method of digital steganography, entitled spread spectrum image steganography (SSIS). Steganography, which means "covered writing" in Greek, is the science of communicating in a hidden manner. Following a discussion of steganographic communication theory and review of existing techniques, the new method, SSIS, is introduced. This system hides and recovers a message of substantial length within digital imagery while maintaining the original image size and dynamic range. The hidden message can be recovered using appropriate keys without any knowledge of the original image. Image restoration, error-control coding, and techniques similar to spread spectrum are described, and the performance of the system is illustrated. A message embedded by this method can be in the form of text, imagery, or any other digital signal. Applications for such a data-hiding scheme include in-band captioning, covert communication, image tamperproofing, authentication, embedded control, and revision tracking.

  15. The Supersymmetric Particle Spectrum

    CERN Document Server

    Barger, V; Ohmann, P

    1994-01-01

    We examine the spectrum of supersymmetric particles predicted by grand unified theoretical (GUT) models where the electroweak symmetry breaking is accomplished radiatively. We evolve the soft supersymmetry breaking parameters according to the renormalization group equations (RGE). The minimization of the Higgs potential is conveniently described by means of tadpole diagrams. We present complete one-loop expressions for these minimization conditions, including contributions from the matter and the gauge sectors. We concentrate on the low $\\tan \\beta$ fixed point region (that provides a natural explanation of a large top quark mass) for which we find solutions to the RGE satisfying both experimental bounds and fine-tuning criteria. We also find that the constraint from the consideration of the lightest supersymmetric particle as the dark matter of the universe is accommodated in much of parameter space where the lightest neutralino is predominantly gaugino. The supersymmetric mass spectrum displays correlations...

  16. AUTISM SPECTRUM DISORDERS (ASD)

    OpenAIRE

    Middha Akanksha; Kataria Sahil; Sandhu Premjeet; Kapoor Bhawna

    2011-01-01

    Autism or Autism Spectrum Disorders (ASD) is a serious neurological disorder affecting communication skills, social interactions, adaptability in an individual, and also causes dramatic changes in behavioral patterns. This condition typically lasts throughout one’s lifetime and affects both, children as well as adults. Research has shown a tenfold increase in autism cases over the past decade and still rising at an alarming pace. The origins of autism are not known even to modern science. Aut...

  17. [Clinical spectrum of neuroborreliosis].

    Science.gov (United States)

    Owecki, Michał K; Kozubski, Wojciech

    2007-01-01

    Lyme disease is a multisystem infectious disease with a wide variety of symptoms involving the skin as well as nervous, musculosceletal and cardiovascular systems. Lyme disease is caused by spirochaete Borrelia burgdorferi transmitted by Ixodes tics in endemic regions. The diverse manifestations of neuroborreliosis require it to be included in differential diagnosis of many neurological disorders. The paper reviews the spectrum of clinical symptoms of nervous system involvement in early and late Lyme disease.

  18. 氮吸附法测定炭黑比表面积的方法研究%The method study of determination of specific surface area of carbon black by a method of nitrogen absorption

    Institute of Scientific and Technical Information of China (English)

    张红梅

    2012-01-01

    A determination method for specific surface area of carbon black was studied. The determination method was method of nitrogen absorption at low temperature and statistical thickness method. That method was small dosage of sample, quick, accurate.%研究炭黑比表面积的测定方法。测定方法为:低温氮吸附法及统计厚度法。该方法样品用量小、速度快,结果准确。

  19. Pharmacotherapy of autism spectrum disorders.

    Science.gov (United States)

    Benvenuto, Arianna; Battan, Barbara; Porfirio, Maria Cristina; Curatolo, Paolo

    2013-02-01

    Although no pharmacological or behavioral therapy has currently proven effective for treating all core symptoms of autism, many dysfunctional behaviors may be treated pharmacologically. Drug treatments should always be part of a comprehensive management plan that includes behavioral and educational interventions, and should be focused on specific targets. Several classes of psychotropic medications have been used to decrease the wide range of "maladaptive" or "interfering" behaviors and associated medical problems that can interfere with relationships and physical health and hinder the implementation of various non-pharmacological interventions. Atypical neuroleptics have been shown to be useful in the treatment of behavioral symptoms in autism. Attention deficit and hyperactivity disorder medications may be effective for counteracting the additional features of hyperactivity and short attention span. Antiepileptic drugs and selective serotonin reuptake inhibitors have shown promising results, but there are no specific indications for them as of yet. With respect to potential drug targets, some clinical features are caused by a dysfunction in neurochemical signaling systems, and thus may improve with selective pharmacological interventions acting on specific abnormal neurobiological pathways. Recent animal studies can be useful models for understanding the common pathogenic pathways leading to autism spectrum disorders (ASDs), and have the potential to offer new biologically focused treatment options.

  20. Spectrum Services 2007

    Science.gov (United States)

    Dobos, L.; Budavári, T.; Csabai, I.; Szalay, A. S.

    2008-10-01

    We present the Filter and Spectrum Services consisting of easy-to-use web applications and web services for searching, plotting and managing large collections of spectral energy distribution data and filter profiles as well as for performing various scientific operations on spectra in a unified framework. The services provide keyword search, advanced query forms and SQL query possibilities for selecting spectra or bandpass curves which may be retrieved in a variety of file formats including XML, VOTable and ASCII. All SDSS DR1-DR5 spectra had been loaded into a database as well as the entire 2dF catalog that adds up to more than 2.5 million SEDs of about a million spatial objects, but registered users can upload their own data making it available for the rest of the community and are free to modify or delete them at any time. Theoretical catalogs, such as the Bruzual-Charlot stochastic burst model spectrum library (100k spectra) and the BaSeL stellar library are also available. Scientific services allow building rest-frame composite spectra out of selected spectra; calculating synthetic magnitudes by convolving spectra with an arbitrary set of bandpass curves of optical instrument filters to generate simulated photometric catalogs on-the-fly; galactic extinction correction, fitting of the continuum using different set of templates (Bruzual-Charlot '03 templates, SDSS eigenspectra), line fitting. All scientific functionalities are available from the web user interface and via the SOAP web services for programmers. MySpectrum is a cross-platform version of the spectrum web service for setting up your own spectrum repository. It integrates into the main service allowing easy access to your data for the whole VO community. The main idea behind our web services is to move scientific functionalities physically close to the database in order to spare network bandwidth. This way scientists may do research without setting up expensive hardware, downloading large datasets

  1. HRT Specification

    CERN Document Server

    Möller, M

    1996-01-01

    In the context of the AIS Project (Advanced Informatics Systems for administration and management) a study has been conducted that resulted in the definition of a high level information systems model. Thirteen proposed systems were defined for detailed analysis. The Finance, Foundation, Human Resources, Logistics and Purchasing areas have been studied in detail. These studies have lead to the purchase and implementation of the ORIAC and SIRIAC packages, the Foundation database, the Oracle HR package, the Triton package and EDH and BHT. This specification describes the Human Resources Toolkit (HRT) intended to be used for accessing data in the HR and Foundation systems. This toolkit should help the divisions carry out their Human Resource management, planning and follow-up. It will have extensive report generation capabilities and offer a variety of standard graphs. It should have an easy-to-use graphical user interface and run on the CERN standard desktop platforms.

  2. Hybrid spread spectrum radio system

    Science.gov (United States)

    Smith, Stephen F [London, TN; Dress, William B [Camas, WA

    2010-02-09

    Systems and methods are described for hybrid spread spectrum radio systems. A method, includes receiving a hybrid spread spectrum signal including: fast frequency hopping demodulating and direct sequence demodulating a direct sequence spread spectrum signal, wherein multiple frequency hops occur within a single data-bit time and each bit is represented by chip transmissions at multiple frequencies.

  3. Specific Phobias

    Science.gov (United States)

    ... Mental Health This information in Spanish ( en español ) Specific phobias Treatment More information on specific phobias A specific ... targeted psychotherapy. Return to top More information on Specific phobias Explore other publications and websites Phobias (Copyright © American ...

  4. Research Progress in Preparation of Sandy Alumina with High Specific Surface Area%高比表面积砂状氧化铝制备研究进展∗

    Institute of Scientific and Technical Information of China (English)

    曹磊; 尹建国; 廖亚龙; 黄斐荣; 王祎洋

    2016-01-01

    Specific surface area,an important parameter of sand-shape Al2 O3 ,has remarkable effects on the characteristics of the product,such as dissolution performance and fluoride absorption ability.The microcosmic mechanism of pore structure′s effect on specific surface area was introduced,and influences of several controlling measures on properties like morphology,size distribution and especially specific surface area during the seeded precipi-tation process of sodium aluminate solution and the calcination process of aluminium hydroxide were discussed.A quick overview of some recent preparation technologies by enhancement with external field and modification of the so-lution system,and the performance of the product were given as well.It′s proposed that the new methods can match the present technology effectively,which means a feasible process for preparing different kinds of products with high specific surface area from metallurgical-grade sandy Al2 O3 to chemistry active Al2 O3 .The way to break through the bottleneck that the intensity of product will decrease with the increase of specific surface area and to obtain sandy Al2 O3 with high quality are still research focuses in the future.%比表面积是砂状 Al2 O3的重要参数,对产品的溶解性能、吸氟能力等特性有显著影响。介绍了影响Al2 O3比表面积的微观孔结构因素,分析了铝酸钠溶液分解过程和氢氧化铝煅烧过程的调控措施对砂状 Al2 O3产品形貌、粒度、比表面积等参数的影响,概述了外场强化、改变溶液体系等新的制备技术及其产品性能。指出各种强化技术可与现行生产工艺相匹配,为产出冶金级砂状 Al2 O3和化学品活性 Al2 O3等不同种类的高比表面积产品提供了新的途径。认为突破强度随比表面积增大而降低这一瓶颈并开发出高质量的砂状Al2 O3依然是今后的一个研究热点。

  5. 蒸汽爆破对蔗渣比表面积及接枝丙烯酰胺的影响%Effect of Steam Explosion on the Bagasse Specific Surface Area and the Graft Degree of Bagasse Grafting Acrylamide

    Institute of Scientific and Technical Information of China (English)

    李锦荣; 马年方; 梁磊; 曾建; 王庆福

    2015-01-01

    以蔗渣比表面积为指标,通过单因素实验考查了蒸汽爆破预处理条件如蒸爆压力、保压时间、蔗渣含水率对爆破后蔗渣比表面积的影响。并以蒸爆后的蔗渣为原料,通过接枝共聚合反应制备蔗渣接枝丙烯酰胺,探讨比表面积对蔗渣接枝聚丙烯酰胺接枝率的影响。结果表明,比表面积的增加有助于提高蔗渣接枝丙烯酰胺的接枝率,最佳蒸爆预处理条件为:蒸爆压力2.0 MPa,保压时间60 s,蔗渣含水率25%。%In this paper, the effect of steam explosion pretreatment conditions, such as steam explosion pressure, pressure maintaining time, water content in bagasse, on bagasse specific surface area were investigated through single factor experiment. The bagasse grafting acrylamide was prepared by grafting copolymerization of acrylamide monomer onto the pretreated bagasse, and the effect of surface area of bagasse on the grafting degree were investigated. The results show that the grafting degree is increased with the specific surface area, and the optimized steam explosion pretreatment conditions are as follows: steam explosion pressure of 2.0 MPa, pressure maintaining time of 60 s, bagasse water content of 25%.

  6. Supernovae anisotropy power spectrum

    CERN Document Server

    Ghodsi, Hoda; Habibi, Farhang

    2016-01-01

    We contribute another anisotropy study to this field of research using Supernovae Type Ia (SNe Ia). In this work, we utilise the power spectrum calculation method and apply it to both the current SNe Ia data and simulation. Our simulations are constructed with the characteristics of the upcoming survey of the Large Synoptic Survey Telescope (LSST), which shall bring us the largest SNe Ia collection to date. We make predictions for the amplitude of a possible dipole anisotropy or anisotropy in higher multipole moments that would be detectable by the LSST.

  7. 2011年上海市浦东新区社区居民急性腹泻病病原谱监测分析%Analysis of pathogen spectrum surveillance of diarrheal patients in Pudong New Area, Shanghai, 2011

    Institute of Scientific and Technical Information of China (English)

    傅益飞; 孙乔; 朱渭萍; 朱林英; 费怡; 叶楚楚; 薛曹怡; 王闻卿; 潘丽峰

    2013-01-01

    Objective To describe the epidemiological and pathogen features of diarrheal patients in Pudong new area, then put forward preventive and treatment work of enteric infectious disease. Methods Syndromic surveillance was conducted in 12 sentinels' outpatients. Pathogen detection was adopted for the samples from diarrheal clinic outpatients. Strains of pathogenic bacteria ( salmonella, vibrio parahaemolyticus and shigella) of stool positive culture were tested a-gainst 12 antimicrobial agents. Results There was a peak during June to September according to outpatients' syndromic surveillance. Of the 1 935 cases, 321 cases (16. 59% ) were positive for bacteria pathogens including 97 (5.01%) cases vibrio parahaemolyticus, 96 cases (4. 96% ) salmonella and 86 cases (4.44% ) campylobacter. Of the 1 327 cases, 188 cases (14. 17% ) were positive for virus pathogens including 110 cases (8. 29% ) norovirus and 37 cases (2. 79% ) rota-virus. Salmonella had the highest susceptibility (99. 0% ) to cefepime and was resistant to nalidixic acid, tetracycline, am-picillin and streptomycin. Shigella had the highest susceptibility (100. 0% ) to chloramphenicol and ofloxacin, meanwhile it had the highest resistant rate (100. 0% ) to amoxicillin, vibrio parahaemolyticus was susceptible to amoxicillin, ceftazi-dime, cefepime and co-trimoxazolewith resistance to gentamicin, amikacin and ciprofloxacin. Conclusions The prevalent months of acute infectious diarrhea are July, August and September. Vibrio parahaemolyticus, salmonella and campylobacter were the main bacteria pathogens while norovirus and rotavirus were the main virus pathogens in Pudong new area. Salmonella, vibrio parahaemolyticus, shigella have varying degrees of resistance to common antibiotics.%目的 了解上海市浦东新区腹泻病的疫情动态、流行规律,掌握上海市浦东新区腹泻病病原谱、菌型分布等特征,为制定防治对策、措施提供科学依据.方法 确定监测病例定义及12个

  8. Autism Spectrum Disorder and Fetal Alcohol Spectrum Disorder. Part II: A Qualitative Comparison of Parenting Stress

    Science.gov (United States)

    Watson, Shelley L.; Hayes, Stephanie A.; Coons, Kelly D.; Radford-Paz, Elisa

    2013-01-01

    Background: Researchers investigating the impact of parenting children with disabilities suggest that regardless of the specific diagnosis, parents experience increased levels of stress. However, particular disabilities may be associated with distinct stressors and strains. Method: Parents of children with autism spectrum disorder (ASD) and…

  9. Very Low Grade Metamorphic Temperatures of the Upper Paleozoic Strata in Northern Daxing’anling Area,NE China:Evidence from Raman Spectrum Studies of Carbonaceous Materials%大兴安岭北部上古生界极低级变质温度来自碳质物拉曼光谱的证据

    Institute of Scientific and Technical Information of China (English)

    胡大千; 王岩泉; 沙茜; 王春光; 陈旭; 马瑞

    2015-01-01

    Using the Renishaw System-1000 laser Raman spectrometer,authors have studied the laser Raman spectrum characteristics of the carbonaceous materials in pelitic rocks outcropped in northern Daxing ’anling area and its indication to the metamorphic temperature.The relationship between the various parameters of the Raman spectrum and the vitrinite reflectance (Ro) of the carbonaceous materials is also discussed.The study shows that the carbonaceous material of Upper Paleozoic pelitic rock has not the Raman spectrum absorption peak of graphite,revealing its metamorphic grade below the low-greenschist facies.Using Raman spectroscopy constructed and proposed by Barker et al.(1 986)and by Rahl et al.(2005),the metamorphic temperature of Upper Paleozoic pelitic rock in the studied area is estimated at 270℃ to 320℃,indicating the Paleozoic strata of the area have merely undergone very low grade metamorphism and metamorphic grade belongs to anchizone.Based on the relationship between the laser Raman spectrometer of carbonaceous materials and the vitrinite reflectance (Ro)proposed by Wang Y,et al.(2002),the Rovalues (maturity of organic materials)of pelitic rocks are estimated to be from 3.03% to 4.23%,consistent with the measured values,showing that the evolution of organic matter of the area is at the over-mature stage,and the pelitic rocks in the area are capable to be generate the hydrocarbon generation and part of the them may have the potential for oil and gas resources.%使用 Renishaw System 1000型激光拉曼光谱仪,研究了大兴安岭北部上古生界泥质岩石碳质物的拉曼光谱特征及其对形成温度的表征,探讨了拉曼光谱参数与镜质体反射率(Ro)的关系。研究表明:研究区上古生界泥质岩石碳质物不具有石墨的拉曼光谱谱带吸收峰,揭示了地层的变质程度未达到低绿片岩相。利用此次经过完善建立的拉曼光谱地质温度计,对大兴安岭北部上古生界泥质岩石变质

  10. Transition from Pervasive Developmental Disorders to Autism Spectrum Disorder: Proposed Changes for the Upcoming DSM-5

    Directory of Open Access Journals (Sweden)

    Banu Tortamis Ozkaya

    2013-06-01

    Full Text Available American Psychiatry Assosiation has scheduled to release The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5 in May 2013. According to the main changes being proposed about autism, there will be one unified Autism Spectrum Disorder diagnosis in the DSM-5 classification. This unified diagnosis will eliminate the distinct diagnostic categories under Pervasive Developmental Disorders in the DSM-IV-TR, namely autistic disorder, asperger syndrome, pervasive developmental disorder-not otherwise specified, and childhood disintegrative disorder. Rett syndrome will be excluded from autism spectrum disorder due to its genetic basis. In addition, severity of symptoms will be measured among individuals with autism spectrum disorder based on the support level required due to the impairment in their lives. The basic rationale behind this revision is that it is better to conceptualize autism as a spectrum including various individuals whose symptoms in different developmental areas range from mild to severe. It is aimed to increase the specificity of autism diagnosis by using one single diagnostic category with its specified severity rather than differentiating several subtypes. The major concern raised over the DSM-5 proposal has been the possibility that some of the individuals who were diagnosed with pervasive developmental disorder according to the DSM-IV-TR might not get a diagnosis in this new system. After the DSM-5 is released, clinical, legal, and educational rearrengements regarding the use of new autism spectrum disorder diagnostic criteria are expected to accelerate worldwide and in Turkey. This paper aims to review briefly the upcoming autism spectrum disorder diagnosis planned to appear in the DSM-5, the rationale of the proposed revision, main critics to the DSM-5 draft that has been publicized, and some of the regulations expected to occur in practice after the changes.

  11. Family-Focused Autism Spectrum Disorder Research: A Review of the Utility of Family Systems Approaches

    Science.gov (United States)

    Cridland, Elizabeth K.; Jones, Sandra C.; Magee, Christopher A.; Caputi, Peter

    2014-01-01

    A family member with an autism spectrum disorder presents pervasive and bidirectional influences on the entire family system, suggesting a need for family-focused autism spectrum disorder research. While there has been increasing interest in this research area, family-focused autism spectrum disorder research can still be considered relatively…

  12. Influence of some factors on alpha energy spectrum of 241Am fire alarm source

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    Several primary factors influencing the alpha energy spectrum of 241Am fire alarm source have been studied in order to get betteralpha energy spectrum.The results show that the homogeneity andthe thickness of metal surface coat and the size of active area of thesource have considerable influence on the alpha energy spectrum of thesource.

  13. Self-disorders and the Schizophrenia Spectrum

    DEFF Research Database (Denmark)

    Nordgaard, Julie; Parnas, Josef

    2014-01-01

    INTRODUCTION: Self-disorders (SD) have been described as a core feature of schizophrenia both in classical and recent psychopathological literature. However, the specificity of SD for the schizophrenia spectrum disorders has never been demonstrated in a diagnostically heterogeneous sample, nor has...... the concurrent validity of SD been examined. AIM: (1) To examine the specificity of Examination of Anomalous Self-Experiences (EASE) measured SD to the schizophrenia spectrum disorder in first contact inpatients, (2) to explore the internal consistency and factorial structure of the EASE, (3) to assess...... the concurrent validity of SD by exploring correlations between SD and the canonical psychopathological dimensions of schizophrenia, (4) to explore relations of SD to intelligence, sociodemographic, and extrinsic illness characteristics. METHODS: A total of 100 consecutive first admission patients underwent...

  14. Transverse myelitis spectrum disorders

    Directory of Open Access Journals (Sweden)

    Pandit Lekha

    2009-01-01

    Full Text Available Acute transverse myelitis (ATM is an inflammatory demyelinating disorder that affects the spinal cord focally resulting in motor sensory and autonomic dysfunction. Establishing the diagnosis of ATM is not as difficult as determining the possible etiology. There is a difference in the perception of ATM seen in the West as compared to developing countries. In the West multiple sclerosis (MS is the most common inflammatory disorder of the central nervous system. An attack of ATM may be the beginning of MS. However, this may not be the case in developing countries where MS is uncommon. Most often transverse myelitis is monophasic and at best represents a site-restricted form of acute disseminated encephalomyelitis (ADEM. Traditionally the combination of optic neuritis and ATM, occurring as a monophasic illness would have been called as neuromyelitis optica (NMO. Changing concepts in the definition of NMO and the discovery of a biomarker, neuromyelitis optica immunoglobulin (NMO_IgG, has changed the way relapsing autoimmune disorders are being perceived currently. A variety of idiopathic inflammatory disorders such as Japanese form of optic spinal MS, recurrent myelitis, and recurrent optic neuritis have been brought under the umbrella of neuromyelitis spectrum disorders because of the association with NMO-IgG. Complete transverse myelitis accompanied by longitudinally extensive transverse myelitis which is seronegative for this biomarker has also been reported from several countries including Japan, Australia, and India. Thus, ATM is a heterogeneous disorder with a varied clinical spectrum, etiology, and outcome.

  15. Hyperbaric oxygen treatment in autism spectrum disorders

    Directory of Open Access Journals (Sweden)

    Rossignol Daniel A

    2012-06-01

    Full Text Available Abstract Traditionally, hyperbaric oxygen treatment (HBOT is indicated in several clinical disorders include decompression sickness, healing of problem wounds and arterial gas embolism. However, some investigators have used HBOT to treat individuals with autism spectrum disorders (ASD. A number of individuals with ASD possess certain physiological abnormalities that HBOT might ameliorate, including cerebral hypoperfusion, inflammation, mitochondrial dysfunction and oxidative stress. Studies of children with ASD have found positive changes in physiology and/or behavior from HBOT. For example, several studies have reported that HBOT improved cerebral perfusion, decreased markers of inflammation and did not worsen oxidative stress markers in children with ASD. Most studies of HBOT in children with ASD examined changes in behaviors and reported improvements in several behavioral domains although many of these studies were not controlled. Although the two trials employing a control group reported conflicting results, a recent systematic review noted several important distinctions between these trials. In the reviewed studies, HBOT had minimal adverse effects and was well tolerated. Studies which used a higher frequency of HBOT sessions (e.g., 10 sessions per week as opposed to 5 sessions per week generally reported more significant improvements. Many of the studies had limitations which may have contributed to inconsistent findings across studies, including the use of many different standardized and non-standardized instruments, making it difficult to directly compare the results of studies or to know if there are specific areas of behavior in which HBOT is most effective. The variability in results between studies could also have been due to certain subgroups of children with ASD responding differently to HBOT. Most of the reviewed studies relied on changes in behavioral measurements, which may lag behind physiological changes. Additional studies

  16. Language and communication in autism spectrum disorders

    Directory of Open Access Journals (Sweden)

    Vinogradova K.N.

    2015-06-01

    Full Text Available The present article is a review of English_language literature on the topic of development of language and communication in people with autism spectrum disorders (ASD. It is shown that language in ASD often differs from the one in typical development, particularly in terms of pragmatics, unusual intonation and echolalia, and difficulties in speech perception and comprehension may also be present. Nevertheless, it should be noted that the results of many studies in this area are controversial due to a variety of reasons and it is hardly possible to reach agreement on many questions in this area.

  17. TPASS: a gamma-ray spectrum analysis and isotope identification computer code

    Energy Technology Data Exchange (ETDEWEB)

    Dickens, J.K.

    1981-03-01

    The gamma-ray spectral data-reduction and analysis computer code TPASS is described. This computer code is used to analyze complex Ge(Li) gamma-ray spectra to obtain peak areas corrected for detector efficiencies, from which are determined gamma-ray yields. These yields are compared with an isotope gamma-ray data file to determine the contributions to the observed spectrum from decay of specific radionuclides. A complete FORTRAN listing of the code and a complex test case are given.

  18. Rotational spectrum of tryptophan

    Energy Technology Data Exchange (ETDEWEB)

    Sanz, M. Eugenia, E-mail: maria.sanz@kcl.ac.uk; Cabezas, Carlos, E-mail: ccabezas@qf.uva.es; Mata, Santiago, E-mail: santiago.mata@uva.es; Alonso, Josè L., E-mail: jlalonso@qf.uva.es [Grupo de Espectroscopia Molecular (GEM), Edificio Quifima, Laboratorios de Espectroscopia y Bioespectroscopia, Unidad Asociada CSIC, Parque Científico Uva, Universidad de Valladolid, 47011 Valladolid (Spain)

    2014-05-28

    The rotational spectrum of the natural amino acid tryptophan has been observed for the first time using a combination of laser ablation, molecular beams, and Fourier transform microwave spectroscopy. Independent analysis of the rotational spectra of individual conformers has conducted to a definitive identification of two different conformers of tryptophan, with one of the observed conformers never reported before. The analysis of the {sup 14}N nuclear quadrupole coupling constants is of particular significance since it allows discrimination between structures, thus providing structural information on the orientation of the amino group. Both observed conformers are stabilized by an O–H···N hydrogen bond in the side chain and a N–H···π interaction forming a chain that reinforce the strength of hydrogen bonds through cooperative effects.

  19. Microwave Spectrum of Hexafluoroisopropanol

    Science.gov (United States)

    Shahi, Abhishek; Mani, Devendra; Arunan, E.

    2012-06-01

    Hexafluoroisopropanol (HFIP) is an important organic solvent and probably the only solvent which can dissolve polythene. IR studies, on this molecule confirm the existence of antiperiplanar (ap) and synclinical (sc) conformers. We have observed pure rotational spectrum of this molecule and the fitted rotational constants (A= 2105.1208(11) MHz, B= 1053.9942(3) MHz, C= 932.3398(3) MHz) confirm the presence of ap conformer. There are many other observed lines which most probably corresponds to sc structure and due to the large amplitude motion of H-atom, some of these transitions show tunneling splitting. Work is in progress for the deuterated (OD) and C-13 isotopologues of the monomer. HFIP is expected to exhibit interesting hydrogen bonding properties and we are planning to investigate them by studying its complex with water. The results will be presented in this talk. H. Schaal, T. Höber, and M. A. Suhm, J. Phys. Chem. A 104, 265 (2000).

  20. Electromagnetic spectrum management system

    Science.gov (United States)

    Seastrand, Douglas R.

    2017-01-31

    A system for transmitting a wireless countermeasure signal to disrupt third party communications is disclosed that include an antenna configured to receive wireless signals and transmit wireless counter measure signals such that the wireless countermeasure signals are responsive to the received wireless signals. A receiver processes the received wireless signals to create processed received signal data while a spectrum control module subtracts known source signal data from the processed received signal data to generate unknown source signal data. The unknown source signal data is based on unknown wireless signals, such as enemy signals. A transmitter is configured to process the unknown source signal data to create countermeasure signals and transmit a wireless countermeasure signal over the first antenna or a second antenna to thereby interfere with the unknown wireless signals.

  1. Autism Spectrum Disorders

    Directory of Open Access Journals (Sweden)

    Rebecca E. Rosenberg

    2011-01-01

    Full Text Available We used a national online registry to examine variation in cumulative prevalence of community diagnosis of psychiatric comorbidity in 4343 children with autism spectrum disorders (ASD. Adjusted multivariate logistic regression models compared influence of individual, family, and geographic factors on cumulative prevalence of parent-reported anxiety disorder, depression, bipolar disorder, and attention deficit/hyperactivity disorder or attention deficit disorder. Adjusted odds of community-assigned lifetime psychiatric comorbidity were significantly higher with each additional year of life, with increasing autism severity, and with Asperger syndrome and pervasive developmental disorder—not otherwise specified compared with autistic disorder. Overall, in this largest study of parent-reported community diagnoses of psychiatric comorbidity, gender, autistic regression, autism severity, and type of ASD all emerged as significant factors correlating with cumulative prevalence. These findings could suggest both underlying trends in actual comorbidity as well as variation in community interpretation and application of comorbid diagnoses in ASD.

  2. Stoppage in Autism Spectrum Disorders

    DEFF Research Database (Denmark)

    Grønborg, Therese Koops; Hansen, Stefan Nygaard; Nielsen, Svend V

    2015-01-01

    of bias in sibling recurrence risk estimation. This study investigated whether stoppage occurs in Danish families with a firstborn child diagnosed with autism spectrum disorders, and if stoppage was differential. We found that stoppage occurs moderately in Danish families affected by autism spectrum...... disorders, and that stoppage is differential. However, differential stoppage is a minor source of estimation bias in Danish sibling recurrence risk studies of autism spectrum disorders....

  3. 200 Area Interim Storage Area Technical Safety Requirements

    Energy Technology Data Exchange (ETDEWEB)

    CARRELL, R.D.

    2000-03-15

    The 200 Area Interim Storage Area Technical Safety Requirements define administrative controls and design features required to ensure safe operation during receipt and storage of canisters containing spent nuclear fuel. This document is based on the 200 Area Interim Storage Area, Annex D, Final Safety Analysis Report which contains information specific to the 200 Area Interim Storage Area.

  4. Scalable Spectrum Sharing Mechanism for Local Area Networks Deployment

    DEFF Research Database (Denmark)

    Da Costa, Gustavo Wagner Oliveira; Cattoni, Andrea Fabio; Kovacs, Istvan Zsolt

    2010-01-01

    The availability on the market of powerful and lightweight mobile devices has led to a fast diffusion of mobile services for end users and the trend is shifting from voice based services to multimedia contents distribution. The current access networks are, however, able to support relatively low...... data rates and with limited Quality of Service (QoS). In order to extend the access to high data rate services to wireless users, the International Telecommunication Union (ITU) established new requirements for future wireless communication technologies of up to 1Gbps in low mobility and up to 100Mbps...

  5. A spectrum of shadowed mirroring.

    Science.gov (United States)

    Wanamaker, Melissa C

    2012-04-01

    The central focus of this paper is to explore and extend Kohut's theory of maternal mirroring and to place it within the current context of psychoanalytic thinking. Kohut believed a child must experience "positive" mirroring from his or her mother in infancy and beyond to ensure development of a healthy self. Kohut alludes, however, to a possible situation in which the mother's face, metaphorically a mirror, can appear "faceless" to her child. From this I have inferred the concept of what I shall call "shadowed mirroring." Clinical and literary examples show that distorted, "shadowed" mirroring appears on a spectrum, with passive mirroring at one end and hostile (either verbal or nonverbal) mirroring on the other; some individuals experience both. I then consider how "shadowed mirroring," especially hostile mirroring, can be understood within the twin contexts of the overall mother-child relationship and present-day Intersubjective/Relational thinking that is both bidirectional and co-constructed. Shadowed mirroring can lead to severe personality dysfunction along the borderline-narcissistic range, as well as to difficulties in the areas of identity formation, failure of self-cohesiveness, and the blunting of certain humane qualities like empathy.

  6. Cat Scratch Disease: Expanded Spectrum

    Science.gov (United States)

    Aziz, Hassan A.; Plesec, Thomas P.; Sabella, Camille; Udayasankar, Unni K.; Singh, Arun D.

    2016-01-01

    Background To expand the spectrum of ophthalmic manifestations in cat scratch disease. Methods Case report. Results A 7-year-old male was referred for evaluation of his left optic disc after failing vision screening test at school. His visual acuity was 20/20 OD and light perception OS. Fundus examination showed a left optic disc lesion associated with an exudative retinal detachment and vitreous seeding. Ultrasonography revealed a 7 × 7.5 × 3.8 mm lesion with a possible 6.3 mm of retrolaminar extension into the substance of the optic nerve. Brain MRI did not show evidence of optic nerve involvement but revealed a 6-mm nodule of the pineal gland suggestive of a pineoblastoma. Enucleation was performed and histopathology revealed a suppurative granulomatous inflammation suggestive of Bartonella infection. Upon further questioning, the patient had recent exposure to kittens with areas of cat scratches along both of his arms. He was subsequently referred to and treated with a 2-week course of trimethoprim-sulfamethoxazole and rifampin by the pediatric infectious disease specialist. Repeat brain MRI showed interval total resolution of enlarged pineal gland. Conclusion: Optic nerve granulomas are a rare presentation of cat scratch disease and could potentially masquerade as retinoblastoma. PMID:27843905

  7. Spectrum handoff algorithm with imperfect spectrum sensing incognitive radio networks

    Science.gov (United States)

    Ma, Bin; Bao, Xiao-min; Xie, Xian-zhong

    2016-10-01

    To guarantee the quality of service of licensed users, the unlicensed users must vacate the occupied channel by spectrum handoff if licensed users appear in the licensed spectrum. However, spectrum sensing with false alarm and missed detection may lead to more inaccuracy problems when unlicensed users perform spectrum handoff. To improve the problems mentioned before, we utilize PRP M/G/1 queuing network model to propose a spectrum handoff algorithm with error data retransmission mechanism and analyze its performance by transmission delay and extended data delivery time. In addition, we discuss the relationship between false alarm probability, extended data delivery time and user traffic load and verify the effectiveness of the proposed algorithm.

  8. Joint switched multi-spectrum and transmit antenna diversity for spectrum sharing systems

    KAUST Repository

    Sayed, Mostafa M.

    2013-10-01

    In spectrum sharing systems, a secondary user (SU) is allowed to share the spectrum with a primary (licensed) network under the condition that the interference observed at the receivers of the primary users (PU-Rxs) is below a predetermined level. In this paper, we consider a secondary network comprised of a secondary transmitter (SU-Tx) equipped with multiple antennas and a single-antenna secondary receiver (SU-Rx) sharing the same spectrum with multiple primary users (PUs), each with a distinct spectrum. We develop transmit antenna diversity schemes at the SU-Tx that exploit the multi-spectrum diversity provided by the existence of multiple PUs so as to optimize the signal-to-noise ratio (SNR) at the SU-Rx. In particular, assuming bounded transmit power at the SU-Tx, we develop switched selection schemes that select the primary spectrum and the SU-Tx transmit antenna that maintain the SNR at the SU-Rx above a specific threshold. Assuming Rayleigh fading channels and binary phase-shift keying (BPSK) transmission, we derive the average bit-error-rate (BER) and average feedback load expressions for the proposed schemes. For the sake of comparison, we also derive a BER expression for the optimal selection scheme that selects the best antenna/spectrum pair that maximizes the SNR at the SU-Rx, in exchange of high feedback load and switching complexity. Finally, we show that our analytical results are in perfect agreement with the simulation results. © 2013 IEEE.

  9. Supporting Dynamic Spectrum Access in Heterogeneous LTE+ Networks

    Energy Technology Data Exchange (ETDEWEB)

    Luiz A. DaSilva; Ryan E. Irwin; Mike Benonis

    2012-08-01

    As early as 2014, mobile network operators’ spectral capac- ity is expected to be overwhelmed by the demand brought on by new devices and applications. With Long Term Evo- lution Advanced (LTE+) networks likely as the future one world 4G standard, network operators may need to deploy a Dynamic Spectrum Access (DSA) overlay in Heterogeneous Networks (HetNets) to extend coverage, increase spectrum efficiency, and increase the capacity of these networks. In this paper, we propose three new management frameworks for DSA in an LTE+ HetNet: Spectrum Accountability Client, Cell Spectrum Management, and Domain Spectrum Man- agement. For these spectrum management frameworks, we define protocol interfaces and operational signaling scenar- ios to support cooperative sensing, spectrum lease manage- ment, and alarm scenarios for rule adjustment. We also quan- tify, through integer programs, the benefits of using DSA in an LTE+ HetNet, that can opportunistically reuse vacant TV and GSM spectrum. Using integer programs, we consider a topology using Geographic Information System data from the Blacksburg, VA metro area to assess the realistic benefits of DSA in an LTE+ HetNet.

  10. Frontal networks in adults with autism spectrum disorder.

    Science.gov (United States)

    Catani, Marco; Dell'Acqua, Flavio; Budisavljevic, Sanja; Howells, Henrietta; Thiebaut de Schotten, Michel; Froudist-Walsh, Seán; D'Anna, Lucio; Thompson, Abigail; Sandrone, Stefano; Bullmore, Edward T; Suckling, John; Baron-Cohen, Simon; Lombardo, Michael V; Wheelwright, Sally J; Chakrabarti, Bhismadev; Lai, Meng-Chuan; Ruigrok, Amber N V; Leemans, Alexander; Ecker, Christine; Consortium, Mrc Aims; Craig, Michael C; Murphy, Declan G M

    2016-02-01

    It has been postulated that autism spectrum disorder is underpinned by an 'atypical connectivity' involving higher-order association brain regions. To test this hypothesis in a large cohort of adults with autism spectrum disorder we compared the white matter networks of 61 adult males with autism spectrum disorder and 61 neurotypical controls, using two complementary approaches to diffusion tensor magnetic resonance imaging. First, we applied tract-based spatial statistics, a 'whole brain' non-hypothesis driven method, to identify differences in white matter networks in adults with autism spectrum disorder. Following this we used a tract-specific analysis, based on tractography, to carry out a more detailed analysis of individual tracts identified by tract-based spatial statistics. Finally, within the autism spectrum disorder group, we studied the relationship between diffusion measures and autistic symptom severity. Tract-based spatial statistics revealed that autism spectrum disorder was associated with significantly reduced fractional anisotropy in regions that included frontal lobe pathways. Tractography analysis of these specific pathways showed increased mean and perpendicular diffusivity, and reduced number of streamlines in the anterior and long segments of the arcuate fasciculus, cingulum and uncinate--predominantly in the left hemisphere. Abnormalities were also evident in the anterior portions of the corpus callosum connecting left and right frontal lobes. The degree of microstructural alteration of the arcuate and uncinate fasciculi was associated with severity of symptoms in language and social reciprocity in childhood. Our results indicated that autism spectrum disorder is a developmental condition associated with abnormal connectivity of the frontal lobes. Furthermore our findings showed that male adults with autism spectrum disorder have regional differences in brain anatomy, which correlate with specific aspects of autistic symptoms. Overall these

  11. Enhancing the Cosmic Shear Power Spectrum

    CERN Document Server

    Simpson, Fergus; Heymans, Catherine; Jimenez, Raul; Verde, Licia

    2015-01-01

    Applying a transformation to a non-Gaussian field can enhance the information content of the resulting power spectrum, by reducing the correlations between Fourier modes. In the context of weak gravitational lensing, it has been shown that this gain in information content is significantly compromised by the presence of shape noise. We apply clipping to mock convergence fields, a technique which is known to be robust in the presence of noise and has been successfully applied to galaxy number density fields. When analysed in isolation the resulting convergence power spectrum returns degraded constraints on cosmological parameters. However substantial gains can be achieved by performing a combined analysis of the power spectra derived from both the original and transformed fields. Even in the presence of realistic levels of shape noise, we demonstrate that this approach is capable of reducing the area of likelihood contours within the $\\Omega_m - \\sigma_8$ plane by more than a factor of three.

  12. DTV protection regions for spectrum sharing

    Directory of Open Access Journals (Sweden)

    Nasir Faruk

    2014-09-01

    Full Text Available In this Letter, the authors propose a technique that allows a secondary user (SU to reuse the spectrum allocated to TV broadcast system. The approach is based on protection view point and an SU is allowed to transmit outside the noise limited contour (grade B contour with additional protection margin. An algorithm was developed that predicts the grade B contour and makes a decision on the availability of the spectrum. The keep-out distance was obtained using the existing path loss models and a model developed based on field strength measurements conducted in the very high frequency (VHF and ultra high frequency (UHF broadcast frequencies. Results of simulation indicate that the extra margin does not follow a linear curve as expected, but strongly depends on the operating frequency and terrain profile of the area. In addition, the measured model's prediction deviates significantly from the other models' prediction.

  13. PINS Spectrum Identification Guide

    Energy Technology Data Exchange (ETDEWEB)

    A.J. Caffrey

    2012-03-01

    The Portable Isotopic Neutron Spectroscopy—PINS, for short—system identifies the chemicals inside munitions and containers without opening them, a decided safety advantage if the fill chemical is a hazardous substance like a chemical warfare agent or an explosive. The PINS Spectrum Identification Guide is intended as a reference for technical professionals responsible for the interpretation of PINS gamma-ray spectra. The guide is divided into two parts. The three chapters that constitute Part I cover the science and technology of PINS. Neutron activation analysis is the focus of Chapter 1. Chapter 2 explores PINS hardware, software, and related operational issues. Gamma-ray spectral analysis basics are introduced in Chapter 3. The six chapters of Part II cover the identification of PINS spectra in detail. Like the PINS decision tree logic, these chapters are organized by chemical element: phosphorus-based chemicals, chlorine-based chemicals, etc. These descriptions of hazardous, toxic, and/or explosive chemicals conclude with a chapter on the identification of the inert chemicals, e.g. sand, used to fill practice munitions.

  14. Spectrum Sharing Security and Attacks in CRNs: a Review

    Directory of Open Access Journals (Sweden)

    Wajdi Alhakami

    2014-01-01

    Full Text Available Cognitive Radio plays a major part in communication technology by resolving the shortage of the spectrum through usage of dynamic spectrum access and artificial intelligence characteristics. The element of spectrum sharing in cognitive radio is a fundamental approach in utilising free channels. Cooperatively communicating cognitive radio devices use the common control channel of the cognitive radio medium access control to achieve spectrum sharing. Thus, the common control channel and consequently spectrum sharing security are vital to ensuring security in the subsequent data communication among cognitive radio nodes. In addition to well known security problems in wireless networks, cognitive radio networks introduce new classes of security threats and challenges, such as licensed user emulation attacks in spectrum sensing and misbehaviours in the common control channel transactions, which degrade the overall network operation and performance. This review paper briefly presents the known threats and attacks in wireless networks before it looks into the concept of cognitive radio and its main functionality. The paper then mainly focuses on spectrum sharing security and its related challenges. Since spectrum sharing is enabled through usage of the common control channel, more attention is paid to the security of the common control channel by looking into its security threats as well as protection and detection mechanisms. Finally, the pros and cons as well as the comparisons of different CR-specific security mechanisms are presented with some open research issues and challenges.

  15. Model-based x-ray energy spectrum estimation algorithm from CT scanning data with spectrum filter

    Science.gov (United States)

    Li, Lei; Wang, Lin-Yuan; Yan, Bin

    2016-10-01

    With the development of technology, the traditional X-ray CT can't meet the modern medical and industry needs for component distinguish and identification. This is due to the inconsistency of X-ray imaging system and reconstruction algorithm. In the current CT systems, X-ray spectrum produced by X-ray source is continuous in energy range determined by tube voltage and energy filter, and the attenuation coefficient of object is varied with the X-ray energy. So the distribution of X-ray energy spectrum plays an important role for beam-hardening correction, dual energy CT image reconstruction or dose calculation. However, due to high ill-condition and ill-posed feature of system equations of transmission measurement data, statistical fluctuations of X ray quantum and noise pollution, it is very hard to get stable and accurate spectrum estimation using existing methods. In this paper, a model-based X-ray energy spectrum estimation method from CT scanning data with energy spectrum filter is proposed. First, transmission measurement data were accurately acquired by CT scan and measurement using phantoms with different energy spectrum filter. Second, a physical meaningful X-ray tube spectrum model was established with weighted gaussian functions and priori information such as continuity of bremsstrahlung and specificity of characteristic emission and estimation information of average attenuation coefficient. The parameter in model was optimized to get the best estimation result for filtered spectrum. Finally, the original energy spectrum was reconstructed from filtered spectrum estimation with filter priori information. Experimental results demonstrate that the stability and accuracy of X ray energy spectrum estimation using the proposed method are improved significantly.

  16. Development of a numerical workflow based on μ-CT imaging for the determination of capillary pressure-saturation-specific interfacial area relationship in 2-phase flow pore-scale porous-media systems: a case study on Heletz sandstone

    Science.gov (United States)

    Peche, Aaron; Halisch, Matthias; Bogdan Tatomir, Alexandru; Sauter, Martin

    2016-05-01

    In this case study, we present the implementation of a finite element method (FEM)-based numerical pore-scale model that is able to track and quantify the propagating fluid-fluid interfacial area on highly complex micro-computed tomography (μ-CT)-obtained geometries. Special focus is drawn to the relationship between reservoir-specific capillary pressure (pc), wetting phase saturation (Sw) and interfacial area (awn). The basis of this approach is high-resolution μ-CT images representing the geometrical characteristics of a georeservoir sample. The successfully validated 2-phase flow model is based on the Navier-Stokes equations, including the surface tension force, in order to consider capillary effects for the computation of flow and the phase-field method for the emulation of a sharp fluid-fluid interface. In combination with specialized software packages, a complex high-resolution modelling domain can be obtained. A numerical workflow based on representative elementary volume (REV)-scale pore-size distributions is introduced. This workflow aims at the successive modification of model and model set-up for simulating, such as a type of 2-phase problem on asymmetric μ-CT-based model domains. The geometrical complexity is gradually increased, starting from idealized pore geometries until complex μ-CT-based pore network domains, whereas all domains represent geostatistics of the REV-scale core sample pore-size distribution. Finally, the model can be applied to a complex μ-CT-based model domain and the pc-Sw-awn relationship can be computed.

  17. Comparative Study of the Specificities of Needling Acupoints DU20, DU26 and HT7 in Intervening Vascular Dementia in Different Areas in the Brain on the Basis of Scale Assessment and Cerebral Functional Imaging

    Institute of Scientific and Technical Information of China (English)

    HUANG Yong; LAI Xin-sheng; TANG An-wu

    2007-01-01

    Objective: Using methods of clinical scale assessment and cerebral functional imaging to compare the relative specificity of needling acupoints Baihui (DU20), Shuigou (DU26) and Shenmen (HT7) in intervening vascular dementia (VD) in different areas in the brain. Methods: Fifty patients with VD were randomized into 5 groups. Needling on conventionally used acupoints of hand and foot three Yang-meridians aiming at hemiplegia was applied to the patients in Group A, and needling on DU20 to Group B, on DU26 to Group C, on HT7 to Group D and on all the three to Group E was applied additionally. Assessments of Mini Mental State Examination (MMSE), Activities of Daily Living (ADL) and Family Attitude Questionnaire (FAQ) were made. And the positron emission computerized tomography (PET) and single photon emission computerized tomography (SPECT) examinations were conducted in 5 selected patients from each group before and after treatment. Results: Needling on conventional acupoints plus DU20 could effect the inner temporal system, thalamencephalon system and prefrontal cortical system to improve memory and executive capacity of VD patients; conventional acupoints plus DU26 could effect more to the prefrontal cortical system to obviously elevate the executive capacity;that plus HT7 would reveal an effect similar to but rather weaker than plus DU20, and effect more to memory; and that plus all the three simultaneously could effect rather roundly multiple aspects of the nervous system related to intellectual activities, to elevate the recognition and enhance the executive capacity. Conclusion: Needling on various acupoints like DU20, DU26 and HT7 have effects on different brain areas.

  18. Seroepidemiological Investigation of Equine Piroplasmosis in Specific Equine Disease-free in Guangzhou area%广州及其周边地区马梨形虫病血清流行病学调查

    Institute of Scientific and Technical Information of China (English)

    沈丹; 薛红; 张海明; 彭聪; 梁卓粤; 彭南秀; 黄捷; 邝惠仪; 谢月优; 胡永辉; 钟江国

    2012-01-01

    In order to found the Specific disease-free Zone for hosting the horse racing during Guangzhou Asian Game, an investigation for the sero prevalence of Equine Piroplasmosis (EP) in this objective area and the adjacent domains (Dongguan and Shenzhen city) in Guangdong province was conducted. An ELISA and the smear microscopy methods were used. The results showed that there were some positive detection rates of antibodies specific to Theileria equi and/or Babesia caballi respectively in Guangzhou, Dongguan and Shenzhen. However, these seropositive racings had no any clinical findings, and no parasites were found by the blood smear microscopy.%为广东从化无规定马属动物疫病区建设的顺利进行和了解周边地区马属动物马梨形虫病的存在情况,采用酶联免疫吸附试验(ELISA)和涂片镜检的方法对广州、东莞和深圳的马属动物进行了马梨形虫病(马巴贝斯虫和驽巴贝斯虫两种虫体)的流行病学调查。结果表明,上述三个地区的马属动物均存在不同程度的马梨形虫病两种虫体的抗体,且出现同一个马场和在同一匹马同时存在两种虫体抗体的情况。对所有抗体阳性马匹进行涂片镜检未发现虫体,也未发现有马梨形虫病,临床症状的马属动物。

  19. Technical Specification for High Yield and High Quality Cultivation of Lianmai 8 in Huaibei Area of Jiangsu Province%江苏淮北地区连麦8号高产优质栽培技术规程

    Institute of Scientific and Technical Information of China (English)

    胡曙鋆; 伏广成; 査日扬; 马永周; 张正球; 许光辉; 韩善红

    2016-01-01

    On the basis of the previous 3 years cultivation experiment and production demonstration, according to the requirement of the national standard of green food production, technical specification for high yield and high quality cultivation of Lianmai 8 in Huaibei area of Jiangsu Prov-ince was formulated.The production factor, fertility index, basic conditions, field management, prevention and control of plant diseases and in-sect pests, harvest and other technical indicators of the high yield cultivation were determined, focusing on the specification of the key technical links such as high yield cultivation management, green prevention and control of plant diseases and insect pests, so as to guide the scale and standardized production of wheat in Huaibei region.%在总结前3年栽培试验和生产示范的基础上,参照国家绿色食品生产规范要求,制定了江苏淮北地区连麦8号高产优质栽培技术规程。规程明确了该品种高产栽培的产量因子、生育指标、基础条件、田间管理、病虫草害防治及收获等技术指标,侧重规范了该品种的高产栽培管理、病虫草害绿色防治等关键技术环节,以指导淮北地区小麦规模化、标准化生产。

  20. Auditory—Spectrum Quantization Based Speech Recognition

    Institute of Scientific and Technical Information of China (English)

    WuYuanqing; HaoJie; 等

    1997-01-01

    Based on the analysis of the physiological and psychological characteristics of human auditory system[1],we can classify human auditory process into two hearing modes:active one and passive one.A novel approach of robust speech recognition,Auditory-spectrum Quantization Based Speech Recognition(AQBSR),is proposed.In this method,we intend to simulate human active hearing mode and locate the effective areas of speech signals in temporal domain and in frequency domain.Adaptive filter banks are used in place of fixed-band filters to extract feature parameters.The effective speech components and their corresponding frequency areas of each word in the vocabulary can be found out during training.In recognition stage,comparison between the unknown sound and the current template is maintained only in the effective areas of the template word.The control experiments show that the AQ BSR method is more robust than traditional systems.

  1. Vitamin D and Autism Spectrum Disorder: A Literature Review

    Directory of Open Access Journals (Sweden)

    Hajar Mazahery

    2016-04-01

    Full Text Available Low vitamin D status in early development has been hypothesised as an environmental risk factor for Autism Spectrum Disorder (ASD, given the concurrent increase in the prevalence of these two conditions, and the association of vitamin D with many ASD-associated medical conditions. Identification of vitamin D-ASD factors may provide indications for primary and secondary prevention interventions. We systematically reviewed the literature for studies on vitamin D-ASD relationship, including potential mechanistic pathways. We identified seven specific areas, including: latitude, season of conception/birth, maternal migration/ethnicity, vitamin D status of mothers and ASD patients, and vitamin D intervention to prevent and treat ASD. Due to differences in the methodological procedures and inconsistent results, drawing conclusions from the first three areas is difficult. Using a more direct measure of vitamin D status—that is, serum 25(OHD level during pregnancy or childhood—we found growing evidence for a relationship between vitamin D and ASD. These findings are supported by convincing evidence from experimental studies investigating the mechanistic pathways. However, with few primary and secondary prevention intervention trials, this relationship cannot be determined, unless randomised placebo-controlled trials of vitamin D as a preventive or disease-modifying measure in ASD patients are available.

  2. [Autism Spectrum Disorder and DSM-5: Spectrum or Cluster?].

    Science.gov (United States)

    Kienle, Xaver; Freiberger, Verena; Greulich, Heide; Blank, Rainer

    2015-01-01

    Within the new DSM-5, the currently differentiated subgroups of "Autistic Disorder" (299.0), "Asperger's Disorder" (299.80) and "Pervasive Developmental Disorder" (299.80) are replaced by the more general "Autism Spectrum Disorder". With regard to a patient-oriented and expedient advising therapy planning, however, the issue of an empirically reproducible and clinically feasible differentiation into subgroups must still be raised. Based on two Autism-rating-scales (ASDS and FSK), an exploratory two-step cluster analysis was conducted with N=103 children (age: 5-18) seen in our social-pediatric health care centre to examine potentially autistic symptoms. In the two-cluster solution of both rating scales, mainly the problems in social communication grouped the children into a cluster "with communication problems" (51 % and 41 %), and a cluster "without communication problems". Within the three-cluster solution of the ASDS, sensory hypersensitivity, cleaving to routines and social-communicative problems generated an "autistic" subgroup (22%). The children of the second cluster ("communication problems", 35%) were only described by social-communicative problems, and the third group did not show any problems (38%). In the three-cluster solution of the FSK, the "autistic cluster" of the two-cluster solution differentiated in a subgroup with mainly social-communicative problems (cluster 1) and a second subgroup described by restrictive, repetitive behavior. The different cluster solutions will be discussed with a view to the new DSM-5 diagnostic criteria, for following studies a further specification of some of the ASDS and FSK items could be helpful.

  3. 抗核抗体荧光模型特异性抗体谱及滴度与自身免疫性疾病的关联性研究%Study on the relationship between antinuclear antibody fluorescence model, specific antibodies spectrum, ti-ter and autoimmune diseases

    Institute of Scientific and Technical Information of China (English)

    李炎梅; 莫思健; 梁太英; 莫显文; 覃平; 何玮; 莫飞; 朱金月

    2014-01-01

    Objective To investigate the relationship between antinuclear antibody ( ANA ) fluorescence model, specific antibodies spectrum, titer and autoimmune diseases(AID).Methods Four hundred and four pa-tients with AID were investigated by using indirect immunofluorescence assay to detect ANA, at the same time, using Europe and Mongolia blotting to detect 15 specific antinuclear antibodies spectrum ( ANAS), and a comparative analy-sis was performed of expression of ANA fluorescence model and the titer and ANA fluorescence model in different dis -eases.Results In AID group the positive rate of ANA was 68.81%, titers in 1∶1 000 accounted for 75.90%.ANA fluorescence model mainly showed cytoplasmic type and nuclear homogeneous type, 130 cases and 108 cases respec-tively.In ANA positive patients, the titer of ANA was higher and fluorescent hybrid model was also increased. Con-clusion The detection rate of ANA was higher in patients with AID. In fluorescent ANA positive patients with high titer the fluorescence model mainly is hybrid model. The simultaneous detection of ANA and ANAS has important clinical significance for diagnosis of autoimmune diseases.%目的:探讨抗核抗体( ANA)荧光模型、滴度及特异性抗体谱与自身免疫性疾病的关联性。方法对404例自身免疫性疾病( AID)患者,同时采用间接免疫荧光法检测ANA和欧蒙印迹法检测15项特异性抗核抗体谱( ANAS),对比分析ANA荧光模型和滴度以及ANA荧光模型在不同疾病中的表达,并与健康体检者300名进行比较。结果在AID组中的ANA检出阳性率为68.81%,滴度在1∶1000以上者占75.90%。检出的ANA荧光模型,以胞浆型和核均质型为主,分别检出130例和108例。 ANA阳性患者滴度升高,检出荧光混合模型的比例也明显增加。结论 AID患者中ANA检出率较高,高滴度的ANA阳性患者荧光模型以混合模型为主,同时检测ANA和ANAS对自身免疫性疾病诊断具有重要的临床意义。

  4. Fabrication of the novel core-shell MCM-41@mTiO2 composite microspheres with large specific surface area for enhanced photocatalytic degradation of dinitro butyl phenol (DNBP)

    Science.gov (United States)

    Wei, Xiao-Na; Wang, Hui-Long; Li, Zhen-Duo; Huang, Zhi-Qiang; Qi, Hui-Ping; Jiang, Wen-Feng

    2016-05-01

    The mesoporous MCM-41@mTiO2 core-shell composite microspheres were synthesized successfully by combining sol-gel and simple hydrothermal treatment. The morphology and microstructure characteristics of the synthesized materials were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), N2 adsorption-desorption measurements, X-ray powder diffraction (XRD), UV-vis diffuse reflectance spectra (UV-vis/DRS) and Fourier transform infrared spectroscopy (FT-IR). The results indicate that the composite material possesses obvious core/shell structure, a pure mesoporous and well-crystallized TiO2 layer (mTiO2), high specific surface area (316.8 m2/g), large pore volume (0.42 cm3/g) and two different pore sizes (2.6 nm and 11.0 nm). The photocatalytic activity of the novel MCM-41@mTiO2 composite was evaluated by degrading 2-sec-butyl-4,6-dinitrophenol (DNBP) in aqueous suspension under UV and visible light irradiation. The results were compared with commercial anatase TiO2 and Degussa P25 and the enhanced degradation were obtained with the synthesized MCM-41@mTiO2 composite under the same conditions, which meant that this material can serve as an efficient photocatalyst for the degradation of hazardous organic pollutants in wastewaters.

  5. A Rorschach investigation of Autism Spectrum Disorders in Adulthood:

    Directory of Open Access Journals (Sweden)

    Manuela Crucitti

    2015-12-01

    Full Text Available Autism is a pervasive developmental disorder characterized by deficits in the areas of communication, socialization and behavior. Current diagnostic criteria have been modified in a restrictive sense, thus the possibility that individuals with milder impairments may not reach the diagnostic threshold is concrete. Furthermore, heterogeneity in phenotypic expression and the high rate of comorbidity with other psychiatric disorders would make even more difficult the diagnostic classification in individuals with autism spectrum disorder (ASD. The present study was a Rorschach investigation aimed to identify specific psychopathological elements to properly orient the diagnosis of ASD in adulthood. Results have shown that the examined subjects were characterized by pragmatism, documented by the presence of details and little details, falls in formal thinking, thought inflexibility, lack of answers with human content, and the prevalence of particular phenomena (denial, perseveration. Data obtained in the study showed a specific pattern of psychopathological signs in adults with ASD, thus suggesting the importance of projective methods for a better understanding of the clinical features of avoidance behaviors and relationships.

  6. True CMB Power Spectrum Estimation

    CERN Document Server

    Paykari, P; Fadili, M J

    2012-01-01

    The cosmic microwave background (CMB) power spectrum is a powerful cosmological probe as it entails almost all the statistical information of the CMB perturbations. Having access to only one sky, the CMB power spectrum measured by our experiments is only a realization of the true underlying angular power spectrum. In this paper we aim to recover the true underlying CMB power spectrum from the one realization that we have without a need to know the cosmological parameters. The sparsity of the CMB power spectrum is first investigated in two dictionaries; Discrete Cosine Transform (DCT) and Wavelet Transform (WT). The CMB power spectrum can be recovered with only a few percentage of the coefficients in both of these dictionaries and hence is very compressible in these dictionaries. We study the performance of these dictionaries in smoothing a set of simulated power spectra. Based on this, we develop a technique that estimates the true underlying CMB power spectrum from data, i.e. without a need to know the cosmo...

  7. AUTISM SPECTRUM DISORDERS (ASD

    Directory of Open Access Journals (Sweden)

    Middha Akanksha

    2011-05-01

    Full Text Available Autism or Autism Spectrum Disorders (ASD is a serious neurological disorder affecting communication skills, social interactions, adaptability in an individual, and also causes dramatic changes in behavioral patterns. This condition typically lasts throughout one’s lifetime and affects both, children as well as adults. Research has shown a tenfold increase in autism cases over the past decade and still rising at an alarming pace. The origins of autism are not known even to modern science. Autism exists at different levels in individuals affected by the disease and is classified into five types. Symptoms for autism are more pronounced and prevalent in children compared to adults. Though some studies attribute autism to gene abnormality, science is yet to furnish hard facts about exact autism causes. Scientists and doctors are also unanimous in their opinion that autism, as of yet, has no cure. Treatments of autism are widely available and help in alleviating the symptoms of autism which make living with the condition easier.Several factors work together in causing autism but isolation and identification of a chief cause or causes has yet to be accomplished by modern science. Some people mistakenly believe that autism is related to bad parenting, vaccinations, or malnutrition. But these misconceptions are due to improper knowledge related to the disease. Symptoms of autism usually surface within the first two years of birth in children. Autistic children usually avoid eye contact and are poor imitators of sound together with a disliking towards a change in routines as well as non adaptability to new environments. At present, there is an absence of medical tests which can diagnose autism. The diagnosis of autism is largely based on developmental history and behavioral patterns. Medicinal treatments of autism have a downside as autism patients develop resistance to certain drugs over long period of use. All types of autism demand a good plan of

  8. Comparative analysis of anti-nuclear antibody pattern detection and specific anti-nuclear antibody spectrum detection%抗核抗体核型检测与特异性抗核抗体谱检测的对比分析

    Institute of Scientific and Technical Information of China (English)

    郑金菊; 牟晓峰

    2014-01-01

    目的:探讨抗核抗体核型与特异性抗核抗体谱的相关性。方法回顾分析本院检验科检测的974例抗核抗体结果,分别用间接免疫荧光法(IIF)检测抗核抗体核型,用条带酶免分析法(LIA)检测特异性抗核抗体谱,分析199例 IIF 与 LIA 同时阳性的结果,比较抗核抗体核型与特异性抗核抗体谱的相关性。结果974例标本中 IIF 阳性249例(阳性率25.6%),LIA 阳性237例(阳性率24.3%),两种方法检测阳性率差异无统计学意义(P >0.05),IIF 与 LIA 单项或两项阳性287例(29.5%),高于IIF 或 LIA 单项检测阳性率,差异有统计学意义(P <0.05)。249例 IIF 阳性中 LIA 阳性199例(79.9%),725例 IIF 阴性中 LIA阴性687例(94.8%)。核颗粒型多见抗 Ro-52抗体,胞浆颗粒型多见抗线粒体 M2抗体,核均质型以抗 dsDNA 抗体、抗核小体抗体多见,着丝点型多见抗着丝点抗体,核仁型多见抗 PM-Scl 抗体。结论IIF-ANA 与 LIA-ANA 有较好的相关性,但也有一定差异,两者联合检测能降低漏检率,对自身免疫性疾病的诊断、病情监测及预后判断有重要意义。%Objective To investigate the correlation between the anti-nuclear antibody(ANA)pattern and the specific ANA spectrum.Methods 974 cases of detected ANA results in our hospital were analyzed retrospectively.The ANA pattern was detec-ted by the indirect immunofluorescence(IIF)and the specific ANA spectrum was tested by the line immunoassay(LIA).199 cases of both simultaneous positive results by IIF and LIA were analyzed and the correlation between ANA patterns and specific ANA spectrum was analyzed.Results Among 974 cases of specimen,249 cases(25.6%)were positive by IIF and 237 cases(24.3%) were positive by LIA,the difference in the positive rate between IIF and LIA had no statistical significance(P >0.05 ).287 cases (29.5%)were positive by single IIF or LIA

  9. Fundamentals of spread spectrum modulation

    CERN Document Server

    Ziemer, Rodger E

    2007-01-01

    This lecture covers the fundamentals of spread spectrum modulation, which can be defined as any modulation technique that requires a transmission bandwidth much greater than the modulating signal bandwidth, independently of the bandwidth of the modulating signal. After reviewing basic digital modulation techniques, the principal forms of spread spectrum modulation are described. One of the most important components of a spread spectrum system is the spreading code, and several types and their characteristics are described. The most essential operation required at the receiver in a spread spect

  10. Broad-spectrum antiviral agents

    Directory of Open Access Journals (Sweden)

    Jun-Da eZhu

    2015-05-01

    Full Text Available Development of highly effective, broad-spectrum antiviral agents is the major objective shared by the fields of virology and pharmaceutics. Antiviral drug development has focused on targeting viral entry and replication, as well as modulating cellular defense system. High throughput screening of molecules, genetic engineering of peptides, and functional screening of agents have identified promising candidates for development of optimal broad-spectrum antiviral agents to intervene in viral infection and control viral epidemics. This review discusses current knowledge, prospective applications, opportunities, and challenges in the development of broad-spectrum antiviral agents.

  11. Cyclostationary Beacon for Assisting Spectrum Sensing in Opportunistic Spectrum Access

    Directory of Open Access Journals (Sweden)

    Thomas Kaiser

    2011-03-01

    Full Text Available Cognitive radio is a promising solution to the problem of spectrum scarcity by means of allowing secondary radio networks access the spectrum opportunistically. One of the most important issues in cognitive radio is how to detect existing over-the-air signals reliably. Not a few literatures have reported that signals could be detected via their inherent or embedded properties. However, this approach may not be reliable and flexible enough for all kinds of signals with different modulation types. In this paper, we propose a type of multitone beacon signal carrying cyclostationary signatures, which is able to enhance the reliability and efficiency of signal detection at low cost of spectrum overhead. This beacon not only can indicate the presence or absence of user signal but also can reveal some other information helpful to opportunistic spectrum access through the information bits carried on its cyclostationary signatures. It could be applied to device/network identification, indication of spectrum allocation and spectrum rendezvous, both for primary and secondary users. Based on our previous work reported in [1], the generation and detection algorithm of the beacon signal are extended with improved spectral efficiency. Performance is discussed with both computer simulation and testbed validation.

  12. Specificity of specific language impairment

    NARCIS (Netherlands)

    GoorhuisBrouwer, SM; WijnbergWilliams, BJ

    1996-01-01

    In children with specific language impairment (SLI) their problems are supposed to be specifically restricted to language. However, both on a theoretical basis as well as on a practical basis it is often difficult to make a sharp distinction between specific and nonspecific language disorders. In a

  13. 控制高毒农药在预防农村急性农药中毒中的意义%Effects of controlling specific dangerous pesticides on prevention of acute pesticide poisoning in rural area

    Institute of Scientific and Technical Information of China (English)

    张平; 赵江霞; 常秀丽; 周志俊

    2010-01-01

    Objective To investigate the effects of controlling the specific dangerous pesticides on prevention of acute pesticide poisoning in rural area. Methods The data of reported cases of pesticide poisoning were analyzed to find out the specific dangerous pesticide in acute pesticide poisoning. Then the occurrence of occupational pesticide poisoning and fatality of non-occupational pesticide poisoning were estimated under the hypothesis of removing the specific dangerous pesticides. Results The data indicated that parathion (including methyl parathion) was the specific dangerous pesticide inducing occupational pesticide poisoning.After removing the use of parathion, the hazard of pesticides which caused occupational pesticide poisoning would be significantly decreased(P<0.01 ). Parathion was also the most dangerous pesticide which caused nonoccupational pesticide poisoning, with its fatality up to 15.8%. If parathion was well controlled, the fatality of non-occupational pesticide poisoning would be declined from 9.4% to 7.4%. The analyses of related literatures also revealed the similar results. Conclusion The occurrence of occupational pesticide poisoning and fatality of non-occupational pesticide poisoning may decrease if the most dangerous pesticides are well supervised.%目的 探讨控制危害最大的农药在预防农村急性农药中毒中所起的作用.方法 通过对某省某县医院既往中毒病例的分析,发现在农村中最易发生中毒的特危农药,假设在控制这些农药后,估测生产性农药中毒的发生和非生产性农药中毒病死率的变化趋势.结果 对硫磷(含甲基对硫磷)是某省某县引起生产性农药中毒危害最大的农药,在控制了对硫磷农药的使用之后,生产性农药中毒危害的大小[生产性农药中毒的例数(A)与非生产性农药中毒的例数(B)的比值]由控制前的0.63下降为0.32,差异有统计学意义(P<0.01).对硫磷同样是引起非生产性农药中毒危害

  14. Towards a worldwide wood economics spectrum.

    Science.gov (United States)

    Chave, Jerome; Coomes, David; Jansen, Steven; Lewis, Simon L; Swenson, Nathan G; Zanne, Amy E

    2009-04-01

    Wood performs several essential functions in plants, including mechanically supporting aboveground tissue, storing water and other resources, and transporting sap. Woody tissues are likely to face physiological, structural and defensive trade-offs. How a plant optimizes among these competing functions can have major ecological implications, which have been under-appreciated by ecologists compared to the focus they have given to leaf function. To draw together our current understanding of wood function, we identify and collate data on the major wood functional traits, including the largest wood density database to date (8412 taxa), mechanical strength measures and anatomical features, as well as clade-specific features such as secondary chemistry. We then show how wood traits are related to one another, highlighting functional trade-offs, and to ecological and demographic plant features (growth form, growth rate, latitude, ecological setting). We suggest that, similar to the manifold that tree species leaf traits cluster around the 'leaf economics spectrum', a similar 'wood economics spectrum' may be defined. We then discuss the biogeography, evolution and biogeochemistry of the spectrum, and conclude by pointing out the major gaps in our current knowledge of wood functional traits.

  15. Autism Spectrum Disorder and intact executive functioning.

    Science.gov (United States)

    Ferrara, R; Ansermet, F; Massoni, F; Petrone, L; Onofri, E; Ricci, P; Archer, T; Ricci, S

    2016-01-01

    Earliest notions concerning autism (Autism Spectrum Disorders, ASD) describe the disturbance in executive functioning. Despite altered definition, executive functioning, expressed as higher cognitive skills required complex behaviors linked to the prefrontal cortex, are defective in autism. Specific difficulties in children presenting autism or verbal disabilities at executive functioning levels have been identified. Nevertheless, the developmental deficit of executive functioning in autism is highly diversified with huge individual variation and may even be absent. The aim of the present study to examine the current standing of intact executive functioning intact in ASD.

  16. Áreas organizativas específicas y circuitos preferentes para patologías prevalentes en urgencias Specific organisational areas and preferential circuits for prevalent pathologies in emergency care

    Directory of Open Access Journals (Sweden)

    M. Sánchez

    2010-01-01

    Full Text Available El incremento de la demanda y las habituales situaciones de colapso de los Servicios de Urgencias Hospitalarios (SUH obliga a continuos cambios organizativos en busca de un óptimo funcionamiento y una asistencia de mayor calidad. Los principales cambios se han basado en la implantación de diferentes sistemas de triaje, a fin de estructurar la atención en función de la urgencia, y el cambio adaptativo en la asistencia médica mediante diferentes fórmulas, como la derivación sin visita, las áreas de visita rápida (fast-track areas y los circuitos asistenciales específicos, como las unidades de dolor torácico, de código ictus o de código sepsis, entre las más extendidas en los SUH. Por otro lado, los SUH se han visto obligados a buscar y utilizar métodos que favorezcan el flujo de salida de los pacientes desde los propios servicios, la mayor parte de las veces entorpecida por la mala gestión de camas hospitalarias por parte de las administraciones sanitarias. Para ello se utilizan diferentes alternativas a la hospitalización convencional como son: unidades de observación, unidades de estancia corta, hospitales de día y hospitalización domiciliaria.The increase in demand and the normal situations of overload of the Hospital Emergency Department (HED make continuous organisational changes compulsory in the search for optimum working and greater quality of care. The main changes have been based on the implementation of different triage systems, with the aim of structuring care according to urgency, and adaptive change in the medical service through different formulae, such as referrals without consultation, fast-track areas and specific care circuits, such as units for thoracic pain, stoke code or sepsis code, amongst the most widespread in HED. On the other hand, HEDs have been forced to seek and use methods that favour the discharge of patients, often hindered by poor management of hospital beds by the health administrations

  17. 安徽亳州地区腹膜透析患者规范洗手状况调查分析%Investigation and Analysis of Peritoneal Dialysis Patients Specification Wash Conditions of Anhui Bozhou Area

    Institute of Scientific and Technical Information of China (English)

    李娜; 王飞龙

    2014-01-01

    Objective Investigation and analysis of peritoneal dialysis patients specification wash conditions of Anhui Bozhou area. Methods used Bozhou Municipal Center for Disease Control to develop standardized questionnaire as hand washing score. Investigate the situation 100 cases of peritoneal dialysis patients wash their hands before the operation. The pass rate of wash hands was 27 per. The pass rate of hands bacterial culture was 18 per. Age , gender were not correlated with hand score (P>0.05),but dialysis age , residence , education level was positively correlated with the hand score (P<0.05), Number of bacteria after washing hands was negatively correlated with hand score (P<0.01). Results The average time of wash hands of the group of patients iwas 9 seconds. Conclusion Peritoneal dialysis patients wash lower pass rate of Anhui Bozhou area. Dialysis age , residence , education level, number of bacteria closely related with the hand score .%目的:调查分析安徽亳州地区腹膜透析(PD)患者规范洗手的现状。方法采用亳州市疾病控制中心制定的规范化洗手调查问卷作为评分标准,对亳州市人民医PD中心的100例PD患者操作前洗手状况进行调查。结果入组患者平均洗手时间为9S。洗手合格率为27%。双手细菌培养合格率为18%。年龄、性别与洗手得分均无相关性(P>0.05),而透析龄、户籍、文化程度与洗手得分呈正相关(P<0.05),洗手后细菌数与洗手得分呈负相关(P<0.01)。结论安徽亳州地区PD患者洗手合格率较低。透析龄、户籍、文化程度洗手后细菌数与洗手得分密切相关。

  18. Physical Retrieval of Surface Emissivity Spectrum from Hyperspectral Infrared Radiances

    Science.gov (United States)

    Li, Jun; Weisz, Elisabeth; Zhou, Daniel K.

    2007-01-01

    Retrieval of temperature, moisture profiles and surface skin temperature from hyperspectral infrared (IR) radiances requires spectral information about the surface emissivity. Using constant or inaccurate surface emissivities typically results in large retrieval errors, particularly over semi-arid or arid areas where the variation in emissivity spectrum is large both spectrally and spatially. In this study, a physically based algorithm has been developed to retrieve a hyperspectral IR emissivity spectrum simultaneously with the temperature and moisture profiles, as well as the surface skin temperature. To make the solution stable and efficient, the hyperspectral emissivity spectrum is represented by eigenvectors, derived from the laboratory measured hyperspectral emissivity database, in the retrieval process. Experience with AIRS (Atmospheric InfraRed Sounder) radiances shows that a simultaneous retrieval of the emissivity spectrum and the sounding improves the surface skin temperature as well as temperature and moisture profiles, particularly in the near surface layer.

  19. Similarity law of fluctuating pressure spectrum beneath hydraulic jump

    Institute of Scientific and Technical Information of China (English)

    LIAN JiJian; WANG JiMin; GU JinDe

    2008-01-01

    Similarity law is the conversion rule between model and prototype, on which a lot of research works have been done, with no agreement reached referring to the similarity law of fluctuating pressure fre-quency spectrum. Experimental data of peak frequency and dominant frequency range of fluctuating pressure spectrum beneath hydraulic jump obtained from serial models of scales 1:1, 1:2 and 1:5 are compared. As a result, similarity law of fluctuating pressure spectrum in the strongly rolling area agrees with the gravity law. As peak frequency and dominant frequencies of fluctuating pressures in hydraulic normalized spectrums of fluctuating pressures show that the similarity nearly agrees with the gravity law.

  20. Autism Spectrum Disorder and Fragile X Syndrome

    Science.gov (United States)

    ... Just Figuring Out CGG Repeats! Donate Print PDF Autism Spectrum Disorder and Fragile X Syndrome Fragile X ... known single gene cause of ASD What Is Autism Spectrum Disorder? Read my Story Autism spectrum disorder ( ...

  1. Genetics Home Reference: ataxia neuropathy spectrum

    Science.gov (United States)

    ... Understand Genetics Home Health Conditions ataxia neuropathy spectrum ataxia neuropathy spectrum Enable Javascript to view the expand/ ... boxes. Download PDF Open All Close All Description Ataxia neuropathy spectrum is part of a group of ...

  2. Fabrication of the novel core-shell MCM-41@mTiO{sub 2} composite microspheres with large specific surface area for enhanced photocatalytic degradation of dinitro butyl phenol (DNBP)

    Energy Technology Data Exchange (ETDEWEB)

    Wei, Xiao-Na; Wang, Hui-Long, E-mail: hlwang@dlut.edu.cn; Li, Zhen-Duo; Huang, Zhi-Qiang; Qi, Hui-Ping; Jiang, Wen-Feng

    2016-05-30

    Graphical abstract: The mesoporous MCM-41@mTiO{sub 2} composite microspheres with core/shell structure, well-crystallized mesoporous TiO{sub 2} layer, high specific surface, large pore volume and excellent photocatalytic activity were synthesized by combining sol-gel and simple hydrothermal treatment. - Highlights: • The mesoporous MCM-41@mTiO{sub 2} composite was synthesized successfully. • The composite was facilely prepared by combining sol-gel and hydrothermal method. • The composite exhibited high photocatalytic degradation activity for DNBP. • The composite photocatalyst has excellent reproducibility. - Abstract: The mesoporous MCM-41@mTiO{sub 2} core-shell composite microspheres were synthesized successfully by combining sol-gel and simple hydrothermal treatment. The morphology and microstructure characteristics of the synthesized materials were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), N{sub 2} adsorption-desorption measurements, X-ray powder diffraction (XRD), UV–vis diffuse reflectance spectra (UV–vis/DRS) and Fourier transform infrared spectroscopy (FT-IR). The results indicate that the composite material possesses obvious core/shell structure, a pure mesoporous and well-crystallized TiO{sub 2} layer (mTiO{sub 2}), high specific surface area (316.8 m{sup 2}/g), large pore volume (0.42 cm{sup 3}/g) and two different pore sizes (2.6 nm and 11.0 nm). The photocatalytic activity of the novel MCM-41@mTiO{sub 2} composite was evaluated by degrading 2-sec-butyl-4,6-dinitrophenol (DNBP) in aqueous suspension under UV and visible light irradiation. The results were compared with commercial anatase TiO{sub 2} and Degussa P25 and the enhanced degradation were obtained with the synthesized MCM-41@mTiO{sub 2} composite under the same conditions, which meant that this material can serve as an efficient photocatalyst for the degradation of hazardous organic pollutants in wastewaters.

  3. 辽东栎冠层叶建成消耗与比叶面积的空间异质性%Spatial Heterogeneity of Specific Leaf Area and Leaf Construction Cost of Quercus liaotungensis Canopy

    Institute of Scientific and Technical Information of China (English)

    覃鑫浩

    2015-01-01

    Plant functional trait has been a hot topic of ecological research in recent years.Specific leaf ar-ea and leaf construction cost are important index factors in the research on harvest and expenditure of re-sources.The vertical and horizontal differences in the energy transmission and micrometeorological charac-teristics of forest canopy can lead to a considerable heterogeneity of functional traits.With Quercus liaotun-gensis,we studied the functional traits and their influence factors of different canopy positions.The results showed that CC on the top is higher than that at the bottom,but it is the other way around to SLA.Except the top and eastward parts,SLA in different canopy positions had significant differences;heat of combus-tion was the main influence factor for CC and SLA.%植物功能性状是目前生态学领域关注的热点问题之一,而比叶面积(Specific Leaf Area,SLA)和叶建成消耗(Leaf Construction Cost,LCC)则是功能性状中研究植物资源收获与支出的首选指标。树冠冠层结构与功能在方向上的不同可导致冠层功能性状空间分布的差异。以东灵山辽东栎为研究对象,分析了不同冠层不同方向部位叶片的功能性状以及影响因素。结果表明:在不同空间上,冠层上部的 CC 均高于冠层底部的,而 SLA 则相反;除上部与东向外,各方向叶片的比叶面积均有显著差异;热值则是影响二者的主要因素。冠层 CC 和 SLA 的空间异质性研究,对于在冠层水平上揭示植物资源利用具有重要意义。

  4. Quantum Entanglement Molecular Absorption Spectrum Simulator

    Science.gov (United States)

    Nguyen, Quang-Viet; Kojima, Jun

    2006-01-01

    Quantum Entanglement Molecular Absorption Spectrum Simulator (QE-MASS) is a computer program for simulating two photon molecular-absorption spectroscopy using quantum-entangled photons. More specifically, QE-MASS simulates the molecular absorption of two quantum-entangled photons generated by the spontaneous parametric down-conversion (SPDC) of a fixed-frequency photon from a laser. The two-photon absorption process is modeled via a combination of rovibrational and electronic single-photon transitions, using a wave-function formalism. A two-photon absorption cross section as a function of the entanglement delay time between the two photons is computed, then subjected to a fast Fourier transform to produce an energy spectrum. The program then detects peaks in the Fourier spectrum and displays the energy levels of very short-lived intermediate quantum states (or virtual states) of the molecule. Such virtual states were only previously accessible using ultra-fast (femtosecond) laser systems. However, with the use of a single-frequency continuous wave laser to produce SPDC photons, and QEMASS program, these short-lived molecular states can now be studied using much simpler laser systems. QE-MASS can also show the dependence of the Fourier spectrum on the tuning range of the entanglement time of any externally introduced optical-path delay time. QE-MASS can be extended to any molecule for which an appropriate spectroscopic database is available. It is a means of performing an a priori parametric analysis of entangled photon spectroscopy for development and implementation of emerging quantum-spectroscopic sensing techniques. QE-MASS is currently implemented using the Mathcad software package.

  5. Vertical profile of the specific surface area and density of the snow at Dome C and on a transect to Dumont D'Urville, Antarctica – albedo calculations and comparison to remote sensing products

    Directory of Open Access Journals (Sweden)

    J.-C. Gallet

    2011-08-01

    Full Text Available The specific surface area (SSA of snow determines in part the albedo of snow surfaces and the capacity of the snow to adsorb chemical species and catalyze reactions. Despite these crucial roles, almost no value of snow SSA are available for the largest permanent snow expanse on Earth, the Antarctic. We report the first extensive study of vertical profiles of snow SSA near Dome C (DC: 75°06' S, 123°20' E, 3233 m a.s.l. on the Antarctic plateau, and at seven sites during the logistical traverse between Dome C and the French coastal base Dumont D'Urville (DDU: 66°40' S, 140°01' E during the Austral summer 2008–2009. We used the DUFISSS system, which measures the IR reflectance of snow at 1310 nm with an integrating sphere. At DC, the mean SSA of the snow in the top 1 cm is 38 m2 kg−1, decreasing monotonically to 14 m2 kg−1 at a depth of 50 cm. Along the traverse, the snow SSA profile is similar to that at DC in the first 600 km from DC. Closer to DDU, the SSA of the top 5 cm is 23 m2 kg−1, decreasing to 19 m2 kg−1 at 50 cm depth. This difference is attributed to wind, which causes a rapid decrease of surface snow SSA, but forms hard windpacks whose SSA decrease more slowly with time. Since light-absorbing impurities are not concentrated enough to affect albedo, the vertical profiles of SSA and density were used to calculate the spectral albedo of the snow for several realistic illumination conditions, using the DISORT radiative transfer model. A preliminary comparison with MODIS data is presented and our calculations and MODIS data show similar trends.

  6. From molecules to behavior: An integrative theory of autism spectrum disorder.

    Science.gov (United States)

    Niculae, Alexandru-Ştefan; Pavăl, Denis

    2016-12-01

    Autism spectrum disorder (ASD) comprises a group of neurodevelopmental disorders for which various theories have been proposed. Each theory brings valuable insights and has experimental evidence backing it, yet none provides an overarching explanation for each of the pathological aspects involved in ASD. Here we present an integrative theory of ASD, centered on a sequence of events spanning from the molecular to the behavioral level. We propose that an abnormality in the interplay between retinoic acid and sex hormones predisposes an individual to specific molecular malfunctions. In turn, this molecular syndrome generates an altered brain connectivity between the cerebellum, the midbrain dopaminergic areas, and the prefrontal cortex. Lastly, this disconnection would generate specific behavioral traits traditionally involved in ASD. Therefore, this paper represents a step forward in unifying different levels of pathological features into novel integrated testable hypotheses.

  7. A pseudo-spectrum analysis of galaxy-galaxy lensing

    Science.gov (United States)

    Hikage, Chiaki; Oguri, Masamune

    2016-10-01

    We present the application of the pseudo-spectrum method to galaxy-galaxy lensing. We derive explicit expressions for the pseudo-spectrum analysis of the galaxy-shear cross-spectrum, which is the Fourier space counterpart of the stacked galaxy-galaxy lensing profile. The pseudo-spectrum method corrects observational issues such as the survey geometry, masks of bright stars and their spikes, and inhomogeneous noise, which distort the spectrum and also mix the E-mode and the B-mode signals. Using ray-tracing simulations in N-body simulations including realistic masks, we confirm that the pseudo-spectrum method successfully recovers the input galaxy-shear cross-spectrum. We also show that the galaxy-shear cross-spectrum has an excess covariance relative to the Gaussian covariance at small scales (k ≳ 1h Mpc-1) where the shot noise is dominated in the Gaussian approximation. We find that the excess is consistent with the expectation from the halo sample variance (HSV), which originates from the matter fluctuations at scales larger than the survey area. We apply the pseudo-spectrum method to the observational data of Canada-France-Hawaii Telescope Lensing survey shear catalogue and three different spectroscopic samples of Sloan Digital Sky Survey Luminous Red Galaxy, and Baryon Oscillation Spectroscopic Survey CMASS and LOWZ galaxies. The galaxy-shear cross-spectra are significantly detected at the level of 7-10σ using the analytic covariance with the HSV contribution included. We also confirm that the observed spectra are consistent with the halo model predictions with the halo occupation distribution parameters estimated from previous work. This work demonstrates the viability of galaxy-galaxy lensing analysis in the Fourier space.

  8. Research on the slope spectrum of the Loess Plateau

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    A new concept dealing with digital analysis of loess terrain,slope spectrum,is presented and discussed in this paper,by introducing its characteristic,represen-tation and extracting method from DEMs. Using 48 geomorphological units in dif-ferent parts of the loess as test areas and 5 m-resolution DEMs as original test data,the quantitative depiction and spatial distribution of slope spectrum in China’s Loess Plateau have been studied on the basis of a series of carefully-designed experiments. In addition,initial experiment indicates a strong relationship between the slope spectrum and the loess landform types,displaying a potential importance of the slope spectrum in geomorphological studies. Based on the slope spectrums derived from the 25 m-resolution DEM data in whole loess terrain in northern part of Shaanxi,13 slope spectrum indices were extracted and integrated into a compre-hensive layer with image integration method. Based on that,a series of unsuper-vised classifications was applied in order to make a landform classification in northern Shaanxi Loess Plateau. Experimental results show that the slope spec-trum analysis is an effective method in revealing the macro landform features. A continuous change of slope spectrum from south to north in northern Shaanxi Loess Plateau shows an obvious spatial distribution of different loess landforms. This also proves the great significance of the slope spectrum method in describing the terrain roughness and landform evolution as well as a further understanding on landform genesis and spatial distribution rule of different landforms in the Loess Plateau.

  9. Novel pricing model for spectrum leasing in secondary spectrum market

    Institute of Scientific and Technical Information of China (English)

    WANG Lei; XU Xing-kun; XU Wen-jun; HE Zhi-qiang; LIN Jia-ru

    2010-01-01

    According to the property rights model of cognitive radio,primary users who own the spectral resource have the right to lease or trade part of it to secondary users in exchange for appropriate profit. In this paper,an implementation of this framework is investigated,where a primary link can lease the owned spectrum to secondary nodes in exchange for cooperation (relaying). A novel pricing model is proposed that enables the trading between spectrum and cooperation. Based on the demand of secondary nodes,the primary link attempts to maximize its quality of service (QoS) by setting the price of spectrum. Taking the price asked by primary link,the secondary nodes aim to obtain most profits by deciding the amount of spectrum to buy and then pay for it by cooperative transmission. The investigated model is conveniently cast in the framework of seller/buyer (Stackelberg) games. Analysis and numerical results show that our pricing model is effective and practical for spectrum leasing based on trading spectral resource for cooperation.

  10. Specific EEG sleep pattern in the prefrontal cortex in primary insomnia.

    Directory of Open Access Journals (Sweden)

    Joy Perrier

    Full Text Available OBJECTIVE: To assess the specific prefrontal activity in comparison to those in the other main cortical areas in primary insomnia patients and in good sleepers. METHODS: Fourteen primary insomnia patients and 11 good sleepers were included in the analysis. Participants completed one night of polysomnography in the sleep lab. Power spectra were calculated during the NREM (Non-rapid eyes movements and the REM (Rapid eyes movements sleep periods at prefrontal, occipital, temporal and central electrode positions. RESULTS: During the NREM sleep, the power spectra did not differ between groups in the prefrontal cortex; while primary insomnia patients exhibited a higher beta power spectrum and a lower delta power spectrum compared to good sleepers in other areas. During the REM sleep, the beta1 power spectrum was lower in the prefrontal cortex in primary insomnia patients compared to good sleepers; while no significant difference between groups was obtained for the other areas. CONCLUSIONS: The present study shows a specific prefrontal sleep pattern during the whole sleep period. In addition, we suggest that primary insomnia patients displayed a dysfunction in the reactivation of the limbic system during the REM sleep and we give additional arguments in favor of a sleep-protection mechanism displayed by primary insomnia patients.

  11. The Spectrum and Laplacian Spectrum of the Dice Lattice

    Science.gov (United States)

    Li, Shuli; Yan, Weigen; Tian, Tao

    2016-07-01

    The dice lattice is the dual lattice of kagomé lattice. Many physical properties on the dice lattice have been studied by physicists, such as Ising model, Glassy dynamics of Josephson arrays, and Lattice Green's function. In this paper, we derive the spectrum and Laplacian spectrum of the dice lattice with toroidal boundary condition. In addition, we apply our results to obtain the formulae of the number of spanning trees, the Kirchhoff index, and the energy of the dice lattice with toroidal boundary condition.

  12. Does sex influence the diagnostic evaluation of autism spectrum disorder in adults?

    Science.gov (United States)

    Wilson, C Ellie; Murphy, Clodagh M; McAlonan, Grainne; Robertson, Dene M; Spain, Debbie; Hayward, Hannah; Woodhouse, Emma; Deeley, P Quinton; Gillan, Nicola; Ohlsen, J Chris; Zinkstok, Janneke; Stoencheva, Vladimira; Faulkner, Jessica; Yildiran, Hatice; Bell, Vaughan; Hammond, Neil; Craig, Michael C; Murphy, Declan Gm

    2016-10-01

    It is unknown whether sex influences the diagnostic evaluation of autism spectrum disorder, or whether male and female adults within the spectrum have different symptom profiles. This study reports sex differences in clinical outcomes for 1244 adults (935 males and 309 females) referred for autism spectrum disorder assessment. Significantly, more males (72%) than females (66%) were diagnosed with an autism spectrum disorder of any subtype (x(2) = 4.09; p = 0.04). In high-functioning autism spectrum disorder adults (IQ > 70; N = 827), there were no significant sex differences in severity of socio-communicative domain symptoms. Males had significantly more repetitive behaviours/restricted interests than females (p = 0.001, d = 0.3). A multivariate analysis of variance indicated a significant interaction between autism spectrum disorder subtype (full-autism spectrum disorder/partial-autism spectrum disorder) and sex: in full-autism spectrum disorder, males had more severe socio-communicative symptoms than females; for partial-autism spectrum disorder, the reverse was true. There were no sex differences in prevalence of co-morbid psychopathologies. Sex influenced diagnostic evaluation in a clinical sample of adults with suspected autism spectrum disorder. The sexes may present with different manifestations of the autism spectrum disorder phenotype and differences vary by diagnostic subtype. Understanding and awareness of adult female repetitive behaviours/restricted interests warrant attention and sex-specific diagnostic assessment tools may need to be considered.

  13. Improving Empathic Communication Skills in Adults with Autism Spectrum Disorder

    Science.gov (United States)

    Koegel, Lynn Kern; Ashbaugh, Kristen; Navab, Anahita; Koegel, Robert L.

    2016-01-01

    The literature suggests that many individuals diagnosed with Autism Spectrum Disorder (ASD) experience challenges with recognizing and describing emotions in others, which may result in difficulties with the verbal expression of empathy during communication. Thus, there is a need for intervention techniques targeting this area. Using a multiple…

  14. Language Acquisition in Autism Spectrum Disorders: A Developmental Review

    Science.gov (United States)

    Eigsti, Inge-Marie; de Marchena, Ashley B.; Schuh, Jillian M.; Kelley, Elizabeth

    2011-01-01

    This paper reviews the complex literature on language acquisition in the autism spectrum disorders (ASD). Because of the high degree of interest in ASD in the past decade, the field has been changing rapidly, with progress in both basic science and applied clinical areas. In addition, psycholinguistically-trained researchers have increasingly…

  15. Changes in Food Selectivity in Children with Autism Spectrum Disorder

    Science.gov (United States)

    Bandini, Linda G.; Curtin, Carol; Phillips, Sarah; Anderson, Sarah E.; Maslin, Melissa; Must, Aviva

    2017-01-01

    Food selectivity is a common problem in children with autism spectrum disorder (ASD) and has an adverse impact on nutrient adequacy and family mealtimes. Despite recent research in this area, few studies have addressed whether food selectivity present in children with ASD persists into adolescence. In this study, we assessed food selectivity in 18…

  16. Sexuality Education for Adolescents and Adults with Autism Spectrum Disorders

    Science.gov (United States)

    Tullis, Christopher A.; Zangrillo, Amanda N.

    2013-01-01

    As people with autism spectrum disorders (ASD) mature from adolescents into adults, social deficits may become more pronounced and apparent in new areas (e.g., social functioning and sexuality). Like neurotypicals, sexuality may be directly related to quality of life for people with ASD. Current practice for addressing sexuality in the ASD…

  17. Tabagismo entre médicos da Região do ABC Paulista Smoking among physicians in a specific region of the greater metropolitan area of São Paulo

    Directory of Open Access Journals (Sweden)

    Adriano Cesar Guazzelli

    2005-12-01

    Full Text Available OBJETIVO: Verificar a prevalência do tabagismo entre os médicos da Região do ABC Paulista e avaliar os métodos de cessação utilizados por esse grupo. MÉTODOS: A amostra constituiu-se de 678 questionários respondidos espontaneamente por médicos cadastrados no Conselho Regional de Medicina do Estado de São Paulo, cujos endereços postais pertenciam à Região do ABC Paulista. RESULTADOS: Observou-se que 58 médicos eram fumantes (8,6%, 183 ex-fumantes (27,0% e 437 não fumantes (64,5%, não havendo diferença significativa em relação ao sexo, entre os fumantes. Não houve diferenças de prevalências entre as várias especialidades médicas. A maioria dos fumantes já havia tentado parar de fumar. O método de cessação do tabagismo mais utilizado foi o da terapia de reposição de nicotina (4,3%, seguido da acupuntura (2,7%. A maioria dos médicos ex-fumantes não utilizou qualquer método para a cessação do tabagismo (88,1%. CONCLUSÃO: A prevalência de tabagistas entre os médicos da Região do ABC Paulista é de 8,6%. A maioria dos médicos que conseguiu parar de fumar, fizeram-no sem a utilização de qualquer método. O método mais utilizado foi o da terapia de reposição de nicotina.OBJECTIVE: To evaluate the prevalence of and describe the methods used to control the smoking habit among a geographically-specific population of physicians. METHODS: Questionnaires were distributed to physicians practicing in a region of the greater metropolitan area of São Paulo area known as the "ABC Paulista" (comprising the municipalities of Santo Andre, São Bernardo and São Caetano, and completed questionnaires were received from 678 physicians, all registered with the São Paulo State Regional Council of Medicine. RESULTS: Of the 678 responding physicians, 58 (8.6% were smokers, 183 (27.0% were former smokers, and 437 (64.5% were nonsmokers. No gender-based differences were found. Nor were there any significant differences in

  18. Preparation of high specific surface area carbon aerogels by conventional drying and their performance in microstructure%超高比表面积碳气凝胶常压干燥制备与结构分析

    Institute of Scientific and Technical Information of China (English)

    刘西川; 袁磊; 王朝阳; 付志兵; 冯灏; 唐永建

    2012-01-01

    Carbon aerogels(CAs) and activated CAs doped with surfactant P123(PEO-PPO-PEO, molecular weight: 5 800) were prepared by conventional drying. SEM images show a handsome network structure of CAs prepared by conventional drying, and the network structure becomes more compact after activation. FTIR spectra show that there is strong interaction between PI 23 and RF (resorcinol-formaldehyde), and P123 disappears after carbonization. TG and DTG curve analyses indicate that the P123 is not a kind of impurity for it decomposes completely after carbonization at 440 ℃. Characterized by nitrogen adsorption, CAs prepared by conventional drying have a high specific surface area of 570 m2 ? g~' , which is up to about 3 500 m2 · g-1 after activation.%以间苯二酚(R)-甲醛(F)为原料,加入表面活性剂P123以增强材料的骨架强度的方法,采用常压干燥技术制备了RF碳气凝胶,并进行了二氧化碳活化以调节其孔结构.扫描电子显微镜(SEM)测试表明,常压干燥的碳气凝胶结构中具有更大的纳米颗粒,骨架结构变粗,活化使碳气凝胶骨架结构更加致密;红外吸收光谱(FTIR)表明,表面活性剂P123中的醚键与RF苯环中的羟基存在强的相互作用,碳化后P123特征峰消失;热重曲线(TG和DTG)分析说明P123在440℃左右分解完全,不会对碳气凝胶的成分产生影响,并能起到良好的造孔作用;氮气吸附表明常压干燥制备的碳气凝胶比表面积约为570m2/g,活化之后的比表面积高达3 500m2/g左右.

  19. Intercomparison of retrieval algorithms for the specific surface area of snow from near-infrared satellite data in mountainous terrain, and comparison with the output of a semi-distributed snowpack model

    Directory of Open Access Journals (Sweden)

    A. Mary

    2013-04-01

    Full Text Available This study compares different methods to retrieve the specific surface area (SSA of snow from satellite radiance measurements in mountainous terrain. It aims at addressing the effect on the retrieval of topographic corrections of reflectance, namely slope and aspect of terrain, multiple reflections on neighbouring slopes and accounting (or not for the anisotropy of snow reflectance. Using MODerate resolution Imaging Spectrometer (MODIS data for six different clear sky scenes spanning a wide range of snow conditions during the winter season 2008–2009 over a domain of 46 × 50 km in the French Alps, we compared SSA retrievals with and without topographic correction, with a spherical or non-spherical snow reflectance model and, in spherical case, with or without anisotropy corrections. The retrieved SSA values were compared to field measurements and to the results of the detailed snowpack model Crocus, fed by driving data from the SAFRAN meteorological analysis. It was found that the difference in terms of surface SSA between retrieved values and SAFRAN-Crocus output was minimal when the topographic correction was taken into account, when using a retrieval method assuming disconnected spherical snow grains. In this case, the root mean square deviation was 9.4 m2 kg−1 and the mean difference was 0.1 m2 kg−1, based on 3170 pairs of observation and simulated values. The added-value of the anisotropy correction was not significant in our case, which may be explained by the presence of mixed pixels and surface roughness. MODIS retrieved data show SSA variations with elevation and aspect which are physically consistent and in good agreement with SAFRAN-Crocus outputs. The variability of the MODIS retrieved SSA within the topographic classes of the model was found to be relatively small (3.9 m2 kg−1. This indicates that semi-distributed snowpack simulations in mountainous terrain with a sufficiently large number of classes provides a

  20. How patients perceive the therapeutic communications skills of their general practitioners, and how that perception affects adherence: use of the TCom-skill GP scale in a specific geographical area

    Directory of Open Access Journals (Sweden)

    Le Bihan Etienne

    2008-12-01

    Full Text Available Abstract Background To study: (1 the structure and test-retest reliability of a measure of how patients perceive the therapeutic communications skills of their general practitioners (TCom-skill GP, and (2 the associations of that scale with socio-demographic and health-related characteristics, and adherence. Methods A total of 393 people who lived in the same geographic area and invited to attend a preventive medical centre for a check up were asked to complete a self-administered questionnaire concerning TCom-skill GP (15 items, socio-demographic and health-related characteristics, and to answer two questions on perceived adherence. Results The average age of respondents was 46.8 years (SD 14, and 50.4% were men. The TCom-skill GP score was one-dimensional, had high internal coherence (Cronbach α 0.92, and good test-retest reliability (intra-class correlation coefficient 0.74. The overall score was positively related to increasing age. Respondents aged 60+ were more likely to be adherent. The higher the score, the higher the probability of adherence. Multivariate analysis showed that the TCom-skill score was associated with advancing age and the number of consultations with the GP during the previous 3 months, but not with gender, living alone, being employed, job category or educational level. Multivariate analysis also showed that adherence was associated with TCom-skill GP score which concealed the association between adherence and advancing age observed in univariate analysis. Conclusion The TCom-skill GP scale probably has value in assessing the quality of doctor-patient relationships and therapeutic communications. The psychometric properties of the TCom-skill GP scale were appropriate for its use in this context. Adherence related to the TCom-skill GP and the latter related to the age of patients and the number of their previous consultations. The TCom-skill GP scale may be a useful way to assess, in a specific geographical location

  1. Gender-specific differences of interaction between obesity and air pollution on stroke and cardiovascular diseases in Chinese adults from a high pollution range area: A large population based cross sectional study

    Energy Technology Data Exchange (ETDEWEB)

    Qin, Xiao-Di [Guangzhou Key Laboratory of Environmental Pollution and Health Risk Assessment, Department of Environmental and Occupational Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080 (China); Qian, Zhengmin [Department of Epidemiology, College for Public Health and Social Justice, Saint Louis University, Saint Louis, MO 63104 (United States); Vaughn, Michael G. [School of Social Work, College for Public Health and Social Justice, Saint Louis University, Saint Louis, MO 63104 (United States); Trevathan, Edwin [Department of Epidemiology, College for Public Health and Social Justice, Saint Louis University, Saint Louis, MO 63104 (United States); Emo, Brett [Department of Environmental and Occupational Health, College for Public Health and Social Justice, Saint Louis University, Saint Louis, MO 63104 (United States); Paul, Gunther [Facuty of Health, School of Public Health and Social Work, Queensland University of Technology, Kelvin Grove, QLD 4059 (Australia); Ren, Wan-Hui [Department of Ambient Air Pollution Monitor, Shenyang Environmental Monitoring Center, Shenyang 110004 (China); Hao, Yuan-Tao [Department of Epidemiology and Biostatistics, School of Public Health, Sun Yat-sen University, Guangzhou 510080 (China); Dong, Guang-Hui, E-mail: donggh5@mail.sysu.edu.cn [Guangzhou Key Laboratory of Environmental Pollution and Health Risk Assessment, Department of Environmental and Occupational Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080 (China)

    2015-10-01

    Background: Little information exists regarding the interaction effects of obesity with long-term air pollution exposure on cardiovascular diseases (CVDs) and stroke in areas of high pollution. The aim of the present study is to examine whether obesity modifies CVD-related associations among people living in an industrial province of northeast China. Methods: We studied 24,845 Chinese adults, aged 18 to 74 years old, from three Northeastern Chinese cities in 2009 utilizing a cross-sectional study design. Body weight and height were measured by trained observers. Overweight and obesity were defined as a body mass index (BMI) between 25–29.9 and ≥ 30 kg/m{sup 2}, respectively. Prevalence rate and related risk factors of cardiovascular and cerebrovascular diseases were investigated by a questionnaire. Three-year (2006–2008) average concentrations of particulate matter (PM{sub 10}), sulfur dioxide (SO{sub 2}), nitrogen dioxides (NO{sub 2}), and ozone (O{sub 3}) were measured by fixed monitoring stations. All the participants lived within 1 km of air monitoring sites. Two-level logistic regression (personal level and district-specific pollutant level) was used to examine these effects, controlling for covariates. Results: We observed significant interactions between exposure and obesity on CVDs and stroke. The associations between annual pollutant concentrations and CVDs and stroke were strongest in obese subjects (OR 1.15–1.47 for stroke, 1.33–1.59 for CVDs), less strong in overweight subjects (OR 1.22–1.35 for stroke, 1.07–1.13 for CVDs), and weakest in normal weight subjects (OR ranged from 0.98–1.01 for stroke, 0.93–1.15 for CVDs). When stratified by gender, these interactions were significant only in women. Conclusions: Study findings indicate that being overweight and obese may enhance the effects of air pollution on the prevalence of CVDs and stroke in Northeastern metropolitan China. Further studies will be needed to investigate the temporality

  2. Note on black hole radiation spectrum in Loop Quantum Gravity

    CERN Document Server

    Diaz-Polo, Jacobo

    2007-01-01

    Recent detailed analysis within the Loop Quantum Gravity calculation of black hole entropy show a stair-like structure in the behavior of entropy as a function of horizon area. The non-trivial distribution of the degeneracy of the black hole horizon area eigenstates is at the origin of this behavior. This degeneracy distribution is analyzed and a phenomenological model is put forward to study the possible implications of this distribution in the black hole radiation spectrum.

  3. Density Spectrums from Kinetic Inflations

    CERN Document Server

    Hwang, J

    1996-01-01

    The pole-like accelerated expansion stages purely driven by the coupling between the gravity and the dilaton field without referring to the potential term can be realized in a class of generalized gravity theories. We consider three such scenarios based on the scalar-tensor gravity, the induced gravity and the string theory. Quantum fluctuations during the expansion stages (including more general situations) can be derived in exact analytic forms. Assuming that the pole-like acceleration stage provides a viable inflation scenario in the early universe we derive the generated classical density spectrums. The generated classical density field shows a generic tilted spectrum with $n \\simeq 4$ which differs from the observed spectrum supporting $n \\simeq 1$.

  4. The Sun's Photospheric Convection Spectrum

    CERN Document Server

    Hathaway, David H; Norton, Aimee A; Kitiashvili, Irina

    2015-01-01

    Spectra of the cellular photospheric flows are determined from full-disk Doppler velocity observations acquired by the Helioseismic and Magnetic Imager (HMI) instrument on the Solar Dynamics Observatory (SDO) spacecraft. Three different analysis methods are used to separately determine spectral coefficients representing the poloidal flows, the toroidal flows, and the radial flows. The amplitudes of these spectral coefficients are constrained by simulated data analyzed with the same procedures as the HMI data. We find that the total velocity spectrum rises smoothly to a peak at a wavenumber of about 120 (wavelength of about 35 Mm), which is typical of supergranules. The spectrum levels off out to wavenumbers of about 400, and then rises again to a peak at a wavenumber of about 3500 (wavelength of about 1200 km), which is typical of granules. The velocity spectrum is dominated by the poloidal flow component (horizontal flows with divergence but no curl) at wavenumbers above 30. The toroidal flow component (hori...

  5. Can the tinnitus spectrum identify tinnitus subgroups?

    NARCIS (Netherlands)

    Heijneman, Karin M.; de Kleine, Emile; Wiersinga-Post, Esther; van Dijk, Pim

    2013-01-01

    The tinnitus spectrum is a psycho-acoustic metric of tinnitus. Previous work found a tight relation between the spectrum and the tone audiogram. This suggests that the spectrum and the audiogram provide essentially the same information, and the added value of the spectrum is limited. In order to tes

  6. Compressive Wideband Spectrum Sensing for Fixed Frequency Spectrum Allocation

    CERN Document Server

    Liu, Yipeng

    2010-01-01

    Too high sampling rate is the bottleneck to wideband spectrum sensing for cognitive radio (CR). As the survey shows that the sensed signal has a sparse representation in frequency domain in the mass, compressed sensing (CS) can be used to transfer the sampling burden to the digital signal processor. An analog to information converter (AIC) can randomly sample the received signal with sub-Nyquist rate to obtained the random measurements. Considering that the static frequency spectrum allocation of primary radios means the bounds between different primary radios is known in advance, here we incorporate information of the spectrum boundaries between different primary user as a priori information to obtain a mixed l2/l1 norm denoising operator (MNDO). In the MNDO, the estimated power spectrum density (PSD) vector is divided into block sections with bounds corresponding different allocated primary radios. Different from previous standard l1-norm constraint on the whole PSD vector, a sum of the l2 norm of each sect...

  7. Anchorage Areas

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — An anchorage area is a place where boats and ships can safely drop anchor. These areas are created in navigable waterways when ships and vessels require them for...

  8. Spread Spectrum Mobile Radio Communications.

    Science.gov (United States)

    1984-09-15

    seconds, yielding Z Y a =XMZ m M .-m The sequence of operacions is illustrated by the matrices of figures ’--3- and 1-3b. Each matrix is either a...sequence of K-bit numbers (code word, address, detection matrix) or a frequency-time spectrogram (traasmit spectrum, receive spectrum). The matrices pertain...and a reduced rank-sum receiver. In figure 3-1, we show the operation of a MRSR by means of matrices . 3-1 Reduced Rank-Sum Receiver With the values of

  9. Autism Spectrum Disorders in Iran

    OpenAIRE

    Mohammadi, Mohammad Reza; Salmanian, Maryam; Akhondzadeh, Shahin

    2011-01-01

    How to Cite this Article: Mohammadi MR, Salmanian M, Akhondzadeh Sh. Autism Spectrum Disorders in Iran. Iranian Journal of Child Neurology2011;5(4):1-9.ObjectiveAutistic disorder, Asperger syndrome, and PDD-Not Otherwise Specified are subsets of autism spectrum disorders (ASDs), which are characterized by impairments in social communication and stereotyped behavior. This article reviews the prevalence, etiology, diagnosis, and treatment of ASDs in Iran.Materials & MethodsWe searched PubMe...

  10. SPECIFIC DEGRADATION OF WATERSHEDS

    Institute of Scientific and Technical Information of China (English)

    Boubacar KANE; Pierre Y.JULIEN

    2007-01-01

    An extensive database of reservoir sedimentation surveys throughout continental United States is compiled and analyzed to determine specific degradation SD relationships as function of mean annual rainfall R, drainage area A, and watershed slope S. The database contains 1463 field measurements and specific degradation relationships are defined as function of A, R and S. Weak trends and significant variability in the data are noticeable. Specific degradation measurements are log normally distributed with respect to R, A, and S and 95% confidence intervals are determined accordingly. The accuracy of the predictions does not significantly increase as more independent variables are added to the regression analyses.

  11. Luminosity Spectrum Reconstruction at Linear Colliders

    CERN Document Server

    Poss, Stéphane

    2014-01-01

    A good knowledge of the luminosity spectrum is mandatory for many measurements at future e+e- colliders. As the beam-parameters determining the luminosity spectrum cannot be measured precisely, the luminosity spectrum has to be measured through a gauge process with the detector. The measured distributions, used to reconstruct the spectrum, depend on Initial State Radiation, cross-section, and Final State Radiation. To extract the basic luminosity spectrum, a parametric model of the luminosity spectrum is created, in this case the spectrum at the 3 TeV Compact Linear Collider (CLIC). The model is used within a reweighting technique to extract the luminosity spectrum from measured Bhabha event observables, taking all relevant effects into account. The centre-of-mass energy spectrum is reconstructed within 5% over the full validity range of the model. The reconstructed spectrum does not result in a significant bias or systematic uncertainty in the exemplary physics benchmark process of smuon pair production.

  12. Reasoning on the Autism Spectrum: A Dual Process Theory Account

    Science.gov (United States)

    Brosnan, Mark; Lewton, Marcus; Ashwin, Chris

    2016-01-01

    Dual process theory proposes two distinct reasoning processes in humans, an intuitive style that is rapid and automatic and a deliberative style that is more effortful. However, no study to date has specifically examined these reasoning styles in relation to the autism spectrum. The present studies investigated deliberative and intuitive reasoning…

  13. Cognitive-Behavioral Therapy for Children with Autism Spectrum Disorders

    Science.gov (United States)

    Rotheram-Fuller, Erin; MacMullen, Laura

    2011-01-01

    Autism spectrum disorders (ASD) represent a continuum of cognitive and social problems that vary considerably in both impact and presentation for each child affected. Although successful interventions have been developed that target specific skill deficits often exhibited by children with autism, many of those interventions are exclusively…

  14. Autism Spectrum Disorder: FRAXE Mutation, a Rare Etiology

    Science.gov (United States)

    Correia, F.; Café, C.; Almeida, J.; Mouga, S.; Oliveira, G.

    2015-01-01

    Autism spectrum disorder (ASD) is characterized by impaired social interaction and communication, restricted interests and repetitive behaviors. Fragile X E is associated with X-linked non-specific mild intellectual disability (ID) and with behavioral problems. Most of the known genetic causes of ASD are also causes of ID, implying that these two…

  15. What's the Scoop on Autism Spectrum Disorders and Nutrition?

    Science.gov (United States)

    Wallace, Lee Shelly

    2009-01-01

    There is much discussion among families about the relationship between nutrition and autism spectrum disorder (ASD). There are claims of diets that will "cure" ASD: gluten-free, casein-free, specific carbohydrate diet (SCD). There are claims of benefits by adding nutrients to the diet, such as vitamin B-6 and magnesium, vitamin B-12, or essential…

  16. Sleep and Behavioral Problems in Children with Autism Spectrum Disorder

    Science.gov (United States)

    Mazurek, Micah O.; Sohl, Kristin

    2016-01-01

    Children with autism spectrum disorder (ASD) are at high risk for sleep disturbance and behavioral dysregulation. However, the relationships between these difficulties are not fully understood. The current study examined the relationships between specific types of sleep and behavioral problems among 81 children with ASD. Sleep problems were…

  17. Intellectual Profiles in the Autism Spectrum and Other Neurodevelopmental Disorders

    Science.gov (United States)

    Mouga, Susana; Café, Cátia; Almeida, Joana; Marques, Carla; Duque, Frederico; Oliveira, Guiomar

    2016-01-01

    The influence of specific autism spectrum disorder (ASD) deficits in Intelligence Quotients (IQ), Indexes and subtests from the Wechsler Intelligence Scale for Children-III was investigated in 445 school-aged children: ASD (N = 224) and other neurodevelopmental disorders (N = 221), matched by Full-Scale IQ and chronological age. ASD have lower…

  18. Chelation Treatment for Autism Spectrum Disorders: A Systematic Review

    Science.gov (United States)

    Davis, Tonya N.; O'Reilly, Mark; Kang, Soyeon; Lang, Russell; Rispoli, Mandy; Sigafoos, Jeff; Lancioni, Giulio; Copeland, Daelynn; Attai, Shanna; Mulloy, Austin

    2013-01-01

    Chelation treatment is used to eliminate specific metals from the body, such as mercury. It has been hypothesized that mercury poisoning may be a factor in autism and data suggest that perhaps 7% of individuals with autism spectrum disorder (ASD) have received chelation treatment. It would therefore seem timely to review studies investigating the…

  19. The Speech Spectrum and its Relationship to Intelligibility of Speech

    Science.gov (United States)

    Englert, Sue Ellen

    The present experiment was designed to investigate and understand the causes of failures of the Articulation Index as a predictive tool. An electroacoustic system was used in which: (1) The frequency response was optimally flattened at the listener's ear. (2) An ear-insert earphone was designed to give close electroacoustic control. (3) An infinite-impulse-response digital filter was used to filter the speech signal from a pre-recorded nonsense syllable test. (4) Four formant regions were filtered in fourteen different ways. It was found that the results agreed with past experiments in that: (1) The Articulation Index fails as a predictive tool when using band-pass filters. (2) Low frequencies seem to mask higher frequencies causing a decrease in intelligibility. It was concluded that: (1) It is inappropriate to relate the total fraction of the speech spectrum to a specific intelligibility score since the fraction remaining after filtering may be in the low-, mid-, or high-frequency range. (2) The relationship between intelligibility and the total area under the spectral curve is not monotonic. (3) The fourth formant region (2925Hz to 4200Hz) enhanced intelligibility when included with other formant regions. Methods for relating spectral regions and intelligibility were discussed.

  20. Using spectrum differentiation and combination for target detection of minerals

    Science.gov (United States)

    Dehnavi, Sahar; Maghsoudi, Yasser; Valadanzoej, Mohammadjavad

    2017-03-01

    Among the techniques that have been developed in spectroscopy, derivative analysis is particularly promising for use with remote sensing data. In the first step of this research we apply the derivative spectrum in a real hyperspectral image and introduce a new target detection approach called "DCEM". For this purpose, 1st to 5th orders of derivative spectrum were applied to the DCEM. The outcome of this research has shown that the application of derivative spectrum in target detection is perfectly advisable in a specific derivative order for each target. This order can be introduced as an optimized order or the Best DCEM. The spectrum differentiation eliminates low frequency components of the spectrum. Despite the little information included in those low frequency components of a signal or spectrum, their complete elimination cause an information loss problem. Hence, in the second step of this research an ensemble classifier approach was employed for the combined use of both spectra and the best derivative order. This simultaneous use of the derivative and zero order spectra is introduced as "ECEM". Experiments were conducted via a HyMap hyperspectral airborne image in eastern Iran. The detection results show that both proposed methods significantly outperform CEM in ROC and AUC values. The best performance upgrade in DCEM detection was about 24% for Kaolinite target and about 28% for Alunite target in ECEM.

  1. CISAPS: Complex Informational Spectrum for the Analysis of Protein Sequences

    Directory of Open Access Journals (Sweden)

    Charalambos Chrysostomou

    2015-01-01

    Full Text Available Complex informational spectrum analysis for protein sequences (CISAPS and its web-based server are developed and presented. As recent studies show, only the use of the absolute spectrum in the analysis of protein sequences using the informational spectrum analysis is proven to be insufficient. Therefore, CISAPS is developed to consider and provide results in three forms including absolute, real, and imaginary spectrum. Biologically related features to the analysis of influenza A subtypes as presented as a case study in this study can also appear individually either in the real or imaginary spectrum. As the results presented, protein classes can present similarities or differences according to the features extracted from CISAPS web server. These associations are probable to be related with the protein feature that the specific amino acid index represents. In addition, various technical issues such as zero-padding and windowing that may affect the analysis are also addressed. CISAPS uses an expanded list of 611 unique amino acid indices where each one represents a different property to perform the analysis. This web-based server enables researchers with little knowledge of signal processing methods to apply and include complex informational spectrum analysis to their work.

  2. Specific Dyslexia.

    Science.gov (United States)

    Naidoo, Sandhya

    The investigation reported in this volume attempts to clarify some issues relating to the existence, nature, and causes of specific dyslexia. Based on an extended study of 98 boys of at least average intelligence with severe reading and spelling problems, the report provides detailed data relating to their developmental and perinatal histories,…

  3. Functional genomics of human brain development and implications for autism spectrum disorders.

    Science.gov (United States)

    Ziats, M N; Grosvenor, L P; Rennert, O M

    2015-10-27

    Transcription of the inherited DNA sequence into copies of messenger RNA is the most fundamental process by which the genome functions to guide development. Encoded sequence information, inherited epigenetic marks and environmental influences all converge at the level of mRNA gene expression to allow for cell-type-specific, tissue-specific, spatial and temporal patterns of expression. Thus, the transcriptome represents a complex interplay between inherited genomic structure, dynamic experiential demands and external signals. This property makes transcriptome studies uniquely positioned to provide insight into complex genetic-epigenetic-environmental processes such as human brain development, and disorders with non-Mendelian genetic etiologies such as autism spectrum disorders. In this review, we describe recent studies exploring the unique functional genomics profile of the human brain during neurodevelopment. We then highlight two emerging areas of research with great potential to increase our understanding of functional neurogenomics-non-coding RNA expression and gene interaction networks. Finally, we review previous functional genomics studies of autism spectrum disorder in this context, and discuss how investigations at the level of functional genomics are beginning to identify convergent molecular mechanisms underlying this genetically heterogeneous disorder.

  4. Optimizing bowtie structure parameters for specific incident light

    Institute of Scientific and Technical Information of China (English)

    Wang Qiao; WU Shi-Fa; Li Xu-Feng; Wang Xiao-Gang

    2010-01-01

    We investigate optical properties of a bowtie-shaped aperture using the finite difference time domain method to optimize its geometric parameters for specific incident lights. The influence of the parameters on local field enhancement and resonant wavelength in the visible frequency range is numerically analysed. It is found that the major resonance of the spectrum is exponentially depended on the bowtie angle but independent of the whole aperture size. The simulation also demonstrates that increasing the aperture size raises the local field intensity on the exit plane due to an enlarged interaction area between the light and the metal medium. And the near-field spot size is closely related to the gap.Based on these results, the design rules of the bowtie structure can be optimized for specific wavelengths excited.

  5. SLAM, a Mathematica interface for SUSY spectrum generators

    Science.gov (United States)

    Marquard, Peter; Zerf, Nikolai

    2014-03-01

    We present and publish a Mathematica package, which can be used to automatically obtain any numerical MSSM input parameter from SUSY spectrum generators, which follow the SLHA standard, like SPheno, SOFTSUSY, SuSeFLAV or Suspect. The package enables a very comfortable way of numerical evaluations within the MSSM using Mathematica. It implements easy to use predefined high scale and low scale scenarios like mSUGRA or mhmax and if needed enables the user to directly specify the input required by the spectrum generators. In addition it supports an automatic saving and loading of SUSY spectra to and from a SQL data base, avoiding the rerun of a spectrum generator for a known spectrum. Catalogue identifier: AERX_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AERX_v1_0.html Program obtainable from: CPC Program Library, Queen’s University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 4387 No. of bytes in distributed program, including test data, etc.: 37748 Distribution format: tar.gz Programming language: Mathematica. Computer: Any computer where Mathematica version 6 or higher is running providing bash and sed. Operating system: Linux. Classification: 11.1. External routines: A SUSY spectrum generator such as SPheno, SOFTSUSY, SuSeFLAV or SUSPECT Nature of problem: Interfacing published spectrum generators for automated creation, saving and loading of SUSY particle spectra. Solution method: SLAM automatically writes/reads SLHA spectrum generator input/output and is able to save/load generated data in/from a data base. Restrictions: No general restrictions, specific restrictions are given in the manuscript. Running time: A single spectrum calculation takes much less than one second on a modern PC.

  6. Phonon spectrum of single-walled boron nitride nanotubes

    Institute of Scientific and Technical Information of China (English)

    Xiao Yang; Yan Xiao-Hong; Cao Jue-Xian; Mao Yu-Liang; Xiang Jun

    2004-01-01

    Based on a force constant model, we investigated the phonon spectrum and then specific heat of single-walled boron nitride nanotubes. The results show that the frequencies of Raman and infrared active modes decrease with increasing diameter in the low frequency, which is consistent with the results calculated by density functional theory.The fitting formulae for diameter and chirality dependence of specific heat at 300K are given.

  7. The Experiences and Needs of Female Adults with High-Functioning Autism Spectrum Disorder

    Science.gov (United States)

    Baldwin, Susanna; Costley, Debra

    2016-01-01

    There is limited large-scale research into the lived experiences of female adults who have an autism spectrum disorder with no co-occurring intellectual disability. Drawing on the findings of an Australia-wide survey, this report presents self-report data from n = 82 women with high-functioning autism spectrum disorder in the areas of health,…

  8. Catatonia and Autistic Spectrum Disorders

    Science.gov (United States)

    Hare, Dougal Julian; Malone, Caroline

    2004-01-01

    The phenomenon of catatonic-like states in people with autistic spectrum disorders is discussed in the context of current knowledge about catatonia as it occurs in severe mental illness and, less frequently documented, in conjunction with developmental disorders. The existing literature on catatonic-like states in people with autistic spectrum…

  9. The low lying glueball spectrum

    Energy Technology Data Exchange (ETDEWEB)

    Adam Szczepaniak; Eric Swanson

    2003-12-18

    The complete low-lying positive charge conjugation glueball spectrum is obtained from QCD. The formalism relies on the construction of an efficient quasiparticle gluon basis for Hamiltonian QCD in Coulomb gauge. The resulting rapidly convergent Fock space expansion is exploited to derive quenched low-lying glueball masses with no free parameters which are in remarkable agreement with lattice gauge theory.

  10. Autism Spectrum Disorders and Epigenetics

    Science.gov (United States)

    Grafodatskaya, Daria; Chung, Brian; Szatmari, Peter; Weksberg, Rosanna

    2010-01-01

    Objective: Current research suggests that the causes of autism spectrum disorders (ASD) are multifactorial and include both genetic and environmental factors. Several lines of evidence suggest that epigenetics also plays an important role in ASD etiology and that it might, in fact, integrate genetic and environmental influences to dysregulate…

  11. Diophantine approximation and automorphic spectrum

    CERN Document Server

    Ghosh, Anish; Nevo, Amos

    2010-01-01

    The present paper establishes qunatitative estimates on the rate of diophantine approximation in homogeneous varieties of semisimple algebraic groups. The estimates established generalize and improve previous ones, and are sharp in a number of cases. We show that the rate of diophantine approximation is controlled by the spectrum of the automorphic representation, and is thus subject to the generalised Ramanujan conjectures.

  12. [Autism spectrum disorders in adults

    NARCIS (Netherlands)

    Kan, C.C.; Buitelaar, J.K.; Gaag, R.J. van der

    2008-01-01

    Early infantile autism' as defined by Kanner has grown into a spectrum of autistic disorders. The recognition of Asperger's disorder and of pervasive developmental disorder not otherwise specified (PDD-NOS), has led to increased demand for appropriate diagnostic assessment of autism in adults. The e

  13. Primordial power spectrum from Planck

    CERN Document Server

    Hazra, Dhiraj Kumar; Souradeep, Tarun

    2014-01-01

    Using modified Richardson-Lucy algorithm we reconstruct the primordial power spectrum (PPS) from Planck Cosmic Microwave Background (CMB) temperature anisotropy data. In our analysis we use different combinations of angular power spectra from Planck to reconstruct the shape of the primordial power spectrum and locate possible features. Performing an extensive error analysis we found the dip near $\\ell\\sim750-850$ represents the most prominent feature in the data. Feature near $\\ell\\sim1800-2000$ is detectable with high confidence only in 217 GHz spectrum and is apparently consequence of a small systematic as described in the revised Planck 2013 papers. Fixing the background cosmological parameters and the foreground nuisance parameters to their best fit baseline values, we report that the best fit power law primordial power spectrum is consistent with the reconstructed form of the PPS at 2$\\sigma$ C.L. of the estimated errors (apart from the local features mentioned above). As a consistency test, we found the...

  14. Army PM UAS Spectrum Update

    Science.gov (United States)

    2012-07-01

    35.15GHz Sierra Nevada Corporation ( SNC ) 1 Aircraft (Wing) J/F-12 06982 TALS TS - Ground Unit RX 34.85 to 35.15GHz TX 34.78 to 35.08GHz Sierra...Nevada Corporation ( SNC ) 2 Runway J/F-12 06982 UNCLASSIFIED UNCLASSIFIED Gray Eagle RF Spectrum Requirements 23 System Component

  15. Neurofeedback in Autism Spectrum Disorders

    Science.gov (United States)

    Holtmann, Martin; Steiner, Sabina; Hohmann, Sarah; Poustka, Luise; Banaschewski, Tobias; Bolte, Sven

    2011-01-01

    Aim: To review current studies on the effectiveness of neurofeedback as a method of treatment of the core symptoms of autism spectrum disorders (ASD). Method: Studies were selected based on searches in PubMed, Ovid MEDLINE, EMBASE, ERIC, and CINAHL using combinations of the following keywords: "Neurofeedback" OR "EEG Biofeedback" OR "Neurotherapy"…

  16. Memory in autistic spectrum disorder.

    Science.gov (United States)

    Boucher, Jill; Mayes, Andrew; Bigham, Sally

    2012-05-01

    Behavioral evidence concerning memory in forms of high-functioning autism (HFA) and in moderately low-functioning autism (M-LFA) is reviewed and compared. Findings on M-LFA are sparse. However, it is provisionally concluded that memory profiles in HFA and M-LFA (relative to ability-matched controls) are similar but that declarative memory impairments are more extensive in M-LFA than in HFA. Specifically, both groups have diminished memory for emotion- or person-related stimuli. Regarding memory for nonsocial stimuli, both groups probably have mental-age-appropriate nondeclarative memory, and within declarative memory, both groups have mental-age-appropriate immediate free recall of within-span or supraspan lists of unrelated items, as well as cued recall and paired associate learning. By contrast, recognition is largely unimpaired in HFA but moderately impaired in M-LFA, and free recall of meaningful or structured stimuli is moderately impaired in HFA but more severely impaired in M-LFA. Theoretical explanations of data on declarative memory in HFA identify problems in the integrative processing, or the consolidation and storage, of complex stimuli or a specific problem of recollection. Proposed neural substrates include the following: disconnectivity of primary sensory and association areas; dysfunctions of medial prefrontal cortex, hippocampus, or posterior parietal lobe; or combinations of these associated with neural disconnectivity. Hypothetically, perirhinal dysfunction might explain the more extensive declarative memory impairments in M-LFA. Foreseeable consequences of uneven memory abilities in HFA and M-LFA are outlined, including possible effects on language and learning in M-LFA. Finally, priorities for future research are identified, highlighting the urgent need for research on memory in lower functioning individuals.

  17. Generalized eigenvalue based spectrum sensing

    KAUST Repository

    Shakir, Muhammad

    2012-01-01

    Spectrum sensing is one of the fundamental components in cognitive radio networks. In this chapter, a generalized spectrum sensing framework which is referred to as Generalized Mean Detector (GMD) has been introduced. In this context, we generalize the detectors based on the eigenvalues of the received signal covariance matrix and transform the eigenvalue based spectrum sensing detectors namely: (i) the Eigenvalue Ratio Detector (ERD) and two newly proposed detectors which are referred to as (ii) the GEometric Mean Detector (GEMD) and (iii) the ARithmetic Mean Detector (ARMD) into an unified framework of generalize spectrum sensing. The foundation of the proposed framework is based on the calculation of exact analytical moments of the random variables of the decision threshold of the respective detectors. The decision threshold has been calculated in a closed form which is based on the approximation of Cumulative Distribution Functions (CDFs) of the respective test statistics. In this context, we exchange the analytical moments of the two random variables of the respective test statistics with the moments of the Gaussian (or Gamma) distribution function. The performance of the eigenvalue based detectors is compared with the several traditional detectors including the energy detector (ED) to validate the importance of the eigenvalue based detectors and the performance of the GEMD and the ARMD particularly in realistic wireless cognitive radio network. Analytical and simulation results show that the newly proposed detectors yields considerable performance advantage in realistic spectrum sensing scenarios. Moreover, the presented results based on proposed approximation approaches are in perfect agreement with the empirical results. © 2012 Springer Science+Business Media Dordrecht.

  18. Energy spectrum of black holes: A new view

    Science.gov (United States)

    Majhi, Abhishek

    2017-01-01

    Energy of a black hole is usually quantized by invoking some area quantization scheme after expressing the energy in terms of the horizon area. However, in this approach one has to quantize the local and asymptotic energy of the black hole separately and the two results do not manifest any physical correspondence with each other. Here, as opposed to this practice, we find the unique energy spectrum of black holes by adopting a top-down approach. The physical links among the underlying quantum theory, statistical mechanics and thermodynamics of the black hole horizon play the central role in determining the energy spectrum. The energy spectrum that we obtain explicitly reveals the correspondence between asymptotic and local observations through the presence of the surface gravity of the horizon as a parameter in the spectrum, rather than being expressed as a function of area and consequently getting quantized in the usual approach. Thus, our result presents a new view as far as black hole energy quantization is concerned. The calculations are performed using the quantum geometric description of black hole horizons as laid down by loop quantum gravity.

  19. Slope spectrum variation in a simulated loess watershed

    Science.gov (United States)

    Li, Fayuan; Tang, Guoan; Wang, Chun; Cui, Lingzhou; Zhu, Rui

    2016-06-01

    A simulated loess watershed, where the loess material and relief properly represent the true loess surface, is adopted to investigate the variation in slope spectrum with loess watershed evolution. The evolution of the simulated loess watershed was driven by the exogenetic force of artificial rainfall. For a period of three months, twenty artificial rainfall events with different intensities and durations were carried out. In the process, nine DEM data sets, each with 10 mm grid resolution, were established by the method of close-range photogrammetry. The slope spectra were then extracted from these DEMs. Subsequent series of carefully designed quantitative analyses indicated a strong relationship between the slope spectrum and the evolution of the simulated loess watershed. Quantitative indices of the slope spectrum varied regularly following the evolution of the simulated loess watershed. Mean slope, slope spectrum information entropy ( H), terrain driving force ( T d ), Mean patch area ( AREA_MN), Contagion Index ( CONTAG), and Patch Cohesion Index ( COHESION) kept increasing following the evolution of the simulated watershed, while skewness ( S), Perimeter-Area Fractal Dimension ( PAFRAC), and Interspersion and Juxtaposition Index ( IJI) represented an opposite trend. All the indices changed actively in the early and active development periods, but slowly in the stable development periods. These experimental results indicate that the time series of slope spectra was able to effectively depict the slope distribution of the simulated loess watershed, thus presenting a potential method for modeling loess landforms.

  20. Digital FMCW for ultrawideband spectrum sensing

    Science.gov (United States)

    Cheema, A. A.; Salous, S.

    2016-08-01

    An ultrawideband digital frequency-modulated continuous wave sensing engine is proposed as an alternative technique for cognitive radio applications. A dual-band demonstrator capable of sensing 750 MHz bandwidth in 204.8 µs is presented. Its performance is illustrated from both bench tests and from real-time measurements of the GSM 900 band and the 2.4 GHz wireless local area network (WLAN) band. The measured sensitivity and noise figure values are -90 dBm for a signal-to-noise ratio margin of at least 10 dB and ~13-14 dB, respectively. Data were collected over 24 h and were analyzed by using the energy detection method. The obtained results show the time variability of occupancy, and considerable sections of the spectrum are unoccupied. In addition, unlike the cyclic temporal variations of spectrum occupancy in the GSM 900 band, the detected variations in the 2.4 GHz WLAN band have an impulsive nature.

  1. Discrete quantum spectrum of black holes

    Energy Technology Data Exchange (ETDEWEB)

    Lochan, Kinjalk, E-mail: kinjalk@iucaa.in; Chakraborty, Sumanta, E-mail: sumanta@iucaa.in

    2016-04-10

    The quantum genesis of Hawking radiation is a long-standing puzzle in black hole physics. Semi-classically one can argue that the spectrum of radiation emitted by a black hole look very much sparse unlike what is expected from a thermal object. It was demonstrated through a simple quantum model that a quantum black hole will retain a discrete profile, at least in the weak energy regime. However, it was suggested that this discreteness might be an artifact of the simplicity of eigen-spectrum of the model considered. Different quantum theories can, in principle, give rise to different complicated spectra and make the radiation from black hole dense enough in transition lines, to make them look continuous in profile. We show that such a hope from a geometry-quantized black hole is not realized as long as large enough black holes are dubbed with a classical mass area relation in any gravity theory ranging from GR, Lanczos–Lovelock to f(R) gravity. We show that the smallest frequency of emission from black hole in any quantum description, is bounded from below, to be of the order of its inverse mass. That leaves the emission with only two possibilities. It can either be non-thermal, or it can be thermal only with the temperature being much larger than 1/M.

  2. W-CDMA - Spread Spectrum

    DEFF Research Database (Denmark)

    Jakobsen, Kaj Bjarne

    1999-01-01

    Specifications, Direct Sequence, Frequency Hopping, Hybrid, W-CDMA, and Power Amplifier Linearisation.......Specifications, Direct Sequence, Frequency Hopping, Hybrid, W-CDMA, and Power Amplifier Linearisation....

  3. Dynamic fair node spectrum allocation for ad hoc networks using random matrices

    Science.gov (United States)

    Rahmes, Mark; Lemieux, George; Chester, Dave; Sonnenberg, Jerry

    2015-05-01

    Dynamic Spectrum Access (DSA) is widely seen as a solution to the problem of limited spectrum, because of its ability to adapt the operating frequency of a radio. Mobile Ad Hoc Networks (MANETs) can extend high-capacity mobile communications over large areas where fixed and tethered-mobile systems are not available. In one use case with high potential impact, cognitive radio employs spectrum sensing to facilitate the identification of allocated frequencies not currently accessed by their primary users. Primary users own the rights to radiate at a specific frequency and geographic location, while secondary users opportunistically attempt to radiate at a specific frequency when the primary user is not using it. We populate a spatial radio environment map (REM) database with known information that can be leveraged in an ad hoc network to facilitate fair path use of the DSA-discovered links. Utilization of high-resolution geospatial data layers in RF propagation analysis is directly applicable. Random matrix theory (RMT) is useful in simulating network layer usage in nodes by a Wishart adjacency matrix. We use the Dijkstra algorithm for discovering ad hoc network node connection patterns. We present a method for analysts to dynamically allocate node-node path and link resources using fair division. User allocation of limited resources as a function of time must be dynamic and based on system fairness policies. The context of fair means that first available request for an asset is not envied as long as it is not yet allocated or tasked in order to prevent cycling of the system. This solution may also save money by offering a Pareto efficient repeatable process. We use a water fill queue algorithm to include Shapley value marginal contributions for allocation.

  4. A methodological framework to distinguish spectrum effects from spectrum biases and to assess diagnostic and screening test accuracy for patient populations: Application to the Papanicolaou cervical cancer smear test

    Directory of Open Access Journals (Sweden)

    Coste Joël

    2008-02-01

    Full Text Available Abstract Background A spectrum effect was defined as differences in the sensitivity or specificity of a diagnostic test according to the patient's characteristics or disease features. A spectrum effect can lead to a spectrum bias when subgroup variations in sensitivity or specificity also affect the likelihood ratios and thus post-test probabilities. We propose and illustrate a methodological framework to distinguish spectrum effects from spectrum biases. Methods Data were collected for 1781 women having had a cervical smear test and colposcopy followed by biopsy if abnormalities were detected (the reference standard. Logistic models were constructed to evaluate both the sensitivity and specificity, and the likelihood ratios, of the test and to identify factors independently affecting the test's characteristics. Results For both tests, human papillomavirus test, study setting and age affected sensitivity or specificity of the smear test (spectrum effect, but only human papillomavirus test and study setting modified the likelihood ratios (spectrum bias for clinical reading, whereas only human papillomavirus test and age modified the likelihood ratios (spectrum bias for "optimized" interpretation. Conclusion Fitting sensitivity, specificity and likelihood ratios simultaneously allows the identification of covariates that independently affect diagnostic or screening test results and distinguishes spectrum effect from spectrum bias. We recommend this approach for the development of new tests, and for reporting test accuracy for different patient populations.

  5. Spectrum Trading in India and 5G

    DEFF Research Database (Denmark)

    Tripathi, Purnendu; Prasad, Ramjee

    2013-01-01

    Currently radio spectrum is largely managed through Command and Control method. Public mobile services require spectrum below 3 GHz for providing cost effective services. The existing method has created artificial shortage of spectrum especially below 3 GHz. Spectrum trading is a new concept...... in which service providers are permitted to purchase spectrum from the market to fulfil their requirements. Spectrum trading has not yet been permitted in India. This paper provides an overview of possibilities of spectrum trading in India and concludes that necessary ingredients are present in India...... for spectrum trading and it could provide a boost to the Indian telecom sector. Further, it will also discuss spectrum issue related with 5G in the direction of millimeter waves....

  6. Principles of spread-spectrum communication systems

    CERN Document Server

    Torrieri, Don

    2015-01-01

    This book provides a concise but lucid explanation of the fundamentals of spread-spectrum systems with an emphasis on theoretical principles. The choice of specific topics is tempered by the author’s judgment of their practical significance and interest to both researchers and system designers. The book contains many improved derivations of the classical theory and presents the latest research results that bring the reader to the frontier of the field. This third edition includes new coverage of topics such as CDMA networks, acquisition and synchronization in DS-CDMA cellular networks, hopsets for FH-CDMA ad hoc networks, implications of information theory, the central limit theorem, the power spectral density of FH/CPM complex envelopes, adaptive filters, and adaptive arrays.   ·         Focuses on the fundamentals of spread-spectrum communication systems and provides current examples of their applications ·         Includes problem sets at the end of each chapter to assist readers in co...

  7. Clinical Genetic Aspects of ASD Spectrum Disorders

    Directory of Open Access Journals (Sweden)

    G. Bradley Schaefer

    2016-01-01

    Full Text Available Early presumptions opined that autism spectrum disorder (ASD was related to the rearing of these children by emotionally-distant mothers. Advances in the 1960s and 1970s clearly demonstrated the biologic basis of autism with a high heritability. Recent advances have demonstrated that specific etiologic factors in autism spectrum disorders can be identified in 30%–40% of cases. Based on early reports newer, emerging genomic technologies are likely to increase this diagnostic yield to over 50%. To date these investigations have focused on etiologic factors that are largely mono-factorial. The currently undiagnosed causes of ASDs will likely be found to have causes that are more complex. Epigenetic, multiple interacting loci, and four dimensional causes (with timing as a variable are likely to be associated with the currently unidentifiable cases. Today, the “Why” is more important than ever. Understanding the causes of ASDs help inform families of important issues such as recurrence risk, prognosis, natural history, and predicting associated co-morbid medical conditions. In the current era of emerging efforts in “personalized medicine”, identifying an etiology will be critical in identifying endo-phenotypic groups and individual variations that will allow for tailored treatment for persons with ASD.

  8. Spectrum Allocation in Two-Tier Networks

    CERN Document Server

    Chandrasekhar, Vikram

    2008-01-01

    Two-tier networks, comprising a conventional cellular network overlaid with shorter range hotspots (e.g. femtocells, distributed antennas, or wired relays), offer an economically viable way to improve cellular system capacity. The capacity-limiting factor in such networks is interference. The cross-tier interference between macrocells and femtocells can suffocate the capacity due to the near-far problem, so in practice hotspots should use a different frequency channel than the potentially nearby high-power macrocell users. Centralized or coordinated frequency planning, which is difficult and inefficient even in conventional cellular networks, is all but impossible in a two-tier network. This paper proposes and analyzes an optimum decentralized spectrum allocation policy for two-tier networks that employ frequency division multiple access (including OFDMA). The proposed allocation is optimal in terms of Area Spectral Efficiency (ASE), and is subjected to a sensible Quality of Service (QoS) requirement, which g...

  9. Behavioral variability and autism spectrum disorder.

    Science.gov (United States)

    Rodriguez, Nicole M; Thompson, Rachel H

    2015-01-01

    Restricted and repetitive behavior is a diagnostic characteristic of autism spectrum disorder (ASD). To the extent that the behavior of individuals with ASD can be conceptualized as problems of invariance, our understanding of environmental variables that influence restricted and repetitive behavior may be informed by the basic and applied literature on response variability. The purposes of this paper are (a) to describe how restricted and repetitive behavior can be conceptualized as problems of invariance, (b) to consider the implications of a lack of varied responding for individuals with ASD, (c) to review relevant basic and applied research on response variability, (d) to present methods to address invariant responding for individuals with ASD, and (e) to suggest areas for future research.

  10. Modelling the TSZ power spectrum

    Energy Technology Data Exchange (ETDEWEB)

    Bhattacharya, Suman [Los Alamos National Laboratory; Shaw, Laurie D [YALE; Nagai, Daisuke [YALE

    2010-01-01

    The structure formation in university is a hierarchical process. As universe evolves, tiny density fluctuations that existed in the early universe grows under gravitational instability to form massive large scale structures. The galaxy clusters are the massive viralized objects that forms by accreting smaller clumps of mass until they collapse under their self-gravity. As such galaxy clusters are the youngest objects in the universe which makes their abundance as a function of mass and redshift, very sensitive to dark energy. Galaxy clusters can be detected by measuring the richness in optical waveband, by measuring the X-ray flux, and in the microwave sky using Sunyaev-Zel'dovich (SZ) effect. The Sunyaev-Zel'dovich (SZ) effect has long been recognized as a powerful tool for detecting clusters and probing the physics of the intra-cluster medium. Ongoing and future experiments like Atacama Cosmology Telescope, the South Pole Telescope and Planck survey are currently surveying the microwave sky to develop large catalogs of galaxy clusters that are uniformly selected by the SZ flux. However one major systematic uncertainties that cluster abundance is prone to is the connection between the cluster mass and the SZ flux. As shown by several simulation studies, the scatter and bias in the SZ flux-mass relation can be a potential source of systematic error to using clusters as a cosmology probe. In this study they take a semi-analytic approach for modeling the intra-cluster medium in order to predict the tSZ power spectrum. The advantage of this approach is, being analytic, one can vary the parameters describing gas physics and cosmology simultaneously. The model can be calibrated against X-ray observations of massive, low-z clusters, and using the SZ power spectrum which is sourced by high-z lower mass galaxy groups. This approach allows us to include the uncertainty in gas physics, as dictated by the current observational uncertainties, while measuring the

  11. Spectrum of energy depositions in the Auger Water Cherenkov Detector

    Science.gov (United States)

    Salazar, Humberto

    1999-08-01

    The measured spectrum of energy depositions in a Water Cherenkov Detector (WCD) prototype for the Pierre Auger Observatory is presented. A WCD (area 10 m2 )is located in the Puebla University campus at a depth of 800 g/cm2 (2200 m above sea level). Differential and integral spectra in a wide energy deposition range (0.5 - 150 of vertical equivalent muons) are presented. The problem of the WCD "self calibration" procedure (by rate of the muon events) is discussed. The characteristic change of the slopes of the differential spectrum at the transition from single muon signals to EAS signals is also discussed. The measured energy deposition spectrum at extreme signals is used to estimate the linearity of the response of the WCD PMTs. Key words: Auger array, water Cherenkov detector, extensive air showers

  12. Spectrum and H(10) of secondary neutrons around Linacs

    Energy Technology Data Exchange (ETDEWEB)

    Ortiz H, A.; Hernandez A, B.; Vega C, H. R.; Hernandez D, V. M. [Unidad Academica de Estudios Nucleares, Universidad Autonoma de Zacatecas, Cipres 10, Fracc. La Penuela, 98068 Zacatecas (Mexico); Rivera M, T. [Centro de Investigacion en Ciencia Aplicada y Tecnologia Avanzada, IPN, Av. Legaria 694, Col. Irrigacion, 11500 Mexico D. F. (Mexico)], e-mail: fermineutron@yahoo.com

    2009-10-15

    Neutron spectrum and ambient dose equivalent has been measured around two 10 MV linear accelerators. Accelerators are Siemens, one is a Mevatron model while another is the Primus. Main differences between those models are the beam collimator and the vault room. Here, Bonner sphere spectrometer with a passive thermal neutron detector has been utilized to measure the neutron spectrum inside the vault. Using an active detector the neutron spectrum was measured by the vaults door of both accelerators. With a neutron area monitor the dose equivalent was measured by the doors. Neutron strength, total fluence rate and ambient dose equivalent were compared, from this was found that shielding conditions are better in the Primus model. (Author)

  13. Spectrum Monitoring Using SpectrumAnalysis LabVIEW Software, Nanoceptors, and Various Digitizing Solutions

    Science.gov (United States)

    2015-02-01

    Spectrum Monitoring Using SpectrumAnalysis LabVIEW Software, Nanoceptors, and Various Digitizing Solutions by Joshua Smith ARL-TR-7217...1138 ARL-TR-7217 February 2015 Spectrum Monitoring Using SpectrumAnalysis LabVIEW Software, Nanoceptors, and Various Digitizing Solutions...REPORT TYPE Final 3. DATES COVERED (From - To) 06/2014–07/2014 4. TITLE AND SUBTITLE Spectrum Monitoring Using Spectrum Analysis LabVIEW

  14. Spectrum and orbit conservation as a factor in future mobile satellite system design

    Science.gov (United States)

    Bowen, Robert R.

    1990-01-01

    Access to the radio spectrum and geostationary orbit is essential to current and future mobile satellite systems. This access is difficult to obtain for current systems, and may be even more so for larger future systems. In this environment, satellite systems that minimize the amount of spectrum orbit resource required to meet a specific traffic requirement are essential. Several spectrum conservation techniques are discussed, some of which are complementary to designing the system at minimum cost. All may need to be implemented to the limits of technological feasibility if network growth is not to be constrained because of the lack of available spectrum-orbit resource.

  15. Angular Spectrum Simulation of Pulsed Ultrasound Fields

    DEFF Research Database (Denmark)

    Du, Yigang; Jensen, Henrik; Jensen, Jørgen Arendt

    2009-01-01

    The optimization of non-linear ultrasound imaging should in a first step be based on simulation, as this makes parameter studies considerably easier than making transducer prototypes. Such a simulation program should be capable of simulating non-linear pulsed fields for arbitrary transducer...... geometries for any kind of focusing and apodization. The Angular Spectrum Approach (ASA) is capable of simulating monochromatic non-linear acoustic wave propagation. However, for ultrasound imaging the time response of each specific point in space is required, and a pulsed ASA simulation with multi temporal....... The RMS error of the pulses for all points in the simulated plane is 10.9%. The good agreement between ASA and Field II simulation for the pulsed ultrasound fields obtained in this paper makes it possible to expand Field II to non-linear pulsed fields....

  16. [Diagnosis of fetal alcohol spectrum disorders].

    Science.gov (United States)

    van Wieringen, Hester; Letteboer, Tom G W; Pereira, Rob Rodrigues; de Ruiter, Sanne; Balemans, Walter A F; Lindhout, Dick

    2010-01-01

    Prenatal alcohol exposure may cause decreased growth of the child, congenital abnormalities, specific facial characteristics, and, most importantly, mental retardation and behavioural disorders, all known as fetal alcohol spectrum disorders (FASD). A significant number of pregnant women in the Netherlands drink alcohol, but the prevalence of FASD in our country is unknown. Repeated and high peak blood alcohol concentrations, for example in the case of binge drinking by the mother, result in more severe abnormalities; a safe limit for alcohol consumption in pregnancy cannot be defined. In 2007 and 2008, Dutch paediatricians reported a total of 56 diagnosed cases of FASD, mostly adopted and foster children. Possibly the condition has not always been diagnosed. Use of international guidelines for diagnosis by the medical profession may improve detection. The guidelines of the Canadian Public Health Agency provide a useful and generally accepted classification, with strict cut-off points to avoid overdiagnosis; attention should always be paid to the broad differential diagnosis.

  17. Competition with Dynamic Spectrum Leasing

    CERN Document Server

    Duan, Lingjie; Shou, Biying

    2010-01-01

    This paper presents a comprehensive analytical study of two competitive cognitive operators' spectrum leasing and pricing strategies, taking into account operators' heterogeneity in leasing costs and users' heterogeneity in transmission power and channel conditions. We model the interactions between operators and users as a three-stage dynamic game, where operators make simultaneous spectrum leasing and pricing decisions in Stages I and II, and users make purchase decisions in Stage III. Using backward induction, we are able to completely characterize the game's equilibria. We show that both operators make the equilibrium leasing and pricing decisions based on simple threshold policies. Moreover, two operators always choose the same equilibrium price despite their difference in leasing costs. Each user receives the same signal-to-noise-ratio (SNR) at the equilibrium, and the obtained payoff is linear in its transmission power and channel gain. We also compare the duopoly equilibrium with the coordinated case ...

  18. Orthopositronium Decay Spectrum using NRQED

    CERN Document Server

    Ruiz-Femenia, P D

    2006-01-01

    As noticed in Ref.[1], the Ore-Powell's classical calculation of the o-Ps -> 3 gamma decay amplitude does not fulfill Low's theorem requirements for the low energy end of the photon spectrum. We reanalyze the implications of Low's theorem applied to this decay considering the interplay between the soft photon limit and the energy scales present in the e+e- system. For energetic photons, the spectrum agrees with the Ore-Powell result, but deviates from it when the photon energy is comparable to the positronium binding energy. In this region it is found that bound states effects are essential to reach agreement with Low's theorem and can be accounted for in the framework of non-relativistic QED.

  19. Image restoration using spectrum estimation

    Science.gov (United States)

    Na, Ki-Woon; Paik, Joon-Ki

    1994-09-01

    A stochastic approach to image restoration is proposed by using various spectrum estimation techniques. In order to estimate the original image from the knowledge of observed image, the minimum mean square error filter or Wiener filter is known to be optimum in the sense of minimizing the mean square error. The optimality of Wiener filter, however, holds only when the power spectra of the original image and noise are given in addition to the transfer function of the imaging system. In practice, the information of the original image is generally not available. In the present paper additive noise is assumed to be white with known variance and the Wiener filter is implemented using various estimation techniques for the original spectrum. The proposed method shows significant improvement over the conventional methods, such as the Wiener filter using constant signal-to-noise power ratio, particularly for images with low signal-to-noise ratio.

  20. Rigidity spectrum of Forbush decrease

    Science.gov (United States)

    Sakakibara, S.; Munakata, K.; Nagashima, K.

    1985-01-01

    Using data from neutron monitors and muon telescopes at surface and underground stations, the average rigidity spectrum of Forbush decreases (Fds) during the period of 1978-1982 were obtained. Thirty eight Ed-events are classified into two groups Hard Fd and Soft Fd according to size of Fd at Sakashita station. It is found that a spectral form of fractional-power type (P to the-gamma sub 1 (P+P sub c) to the -gamma sub2) is more suitable for the present purpose than that of power-exponential type or of power type with an upper limiting rigidity. The best fitted spectrum of fractional-power type is expressed by gamma sub1 = 0.37, gamma sub2 = 0.89 and P subc = 10 GV for Hard Fd and gamma sub1 = 0.77, gamma sub2 = 1.02 and P sub c - 14GV for Soft Fd.

  1. Dynamic Spectrum Sharing among Femtocells

    DEFF Research Database (Denmark)

    Da Costa, Gustavo Wagner Oliveira

    2012-01-01

    The ever-growing demand for mobile broadband is leading to an imminent spectrum scarcity. In order to cope with such situation dynamic spectrum sharing and the widespread deployment of small cells (femtocells) are promising solutions. Delivering such a view is not short of challenges. Massive...... for scalability to a large number of cells, stability and limited complexity. The work represents an evolution towards future cognitive femtocells. The issue of inter-cell interference among femtocells is thoroughly analyzed with game theory, graph theory and system-level simulations. These analyses show...... that the interference should be managed, and the frequency reuse should be dynamically adapted locally. Three different methods are proposed. Two of them completely avoid the need for signaling among different cells, and the third method involves the setting of mutual agreements among neighbor cells. These methods...

  2. Patient-Specific Computational Modeling

    CERN Document Server

    Peña, Estefanía

    2012-01-01

    This book addresses patient-specific modeling. It integrates computational modeling, experimental procedures, imagine clinical segmentation and mesh generation with the finite element method (FEM) to solve problems in computational biomedicine and bioengineering. Specific areas of interest include cardiovascular problems, ocular and muscular systems and soft tissue modeling. Patient-specific modeling has been the subject of serious research over the last seven years and interest in the area is continually growing and this area is expected to further develop in the near future.

  3. 天津及周边地区苯丙氨酸羟化酶基因突变谱和新突变分析%Mutation spectrum of phenylalanine hydroxylase gene in patients with phenylketonuria in Tianjin and surrounding areas of Northern China

    Institute of Scientific and Technical Information of China (English)

    宋力; 党利亨; 孟英韬; 付伯津

    2010-01-01

    common mutations included 243Q (36/198,18.18%), V399V (22/198, 11. 1%), R111X (19/198,9.6%), E6nt-96A→g (18/198, 9.1%), R413P (15/198, 7.6%) and Y356X (13/198, 6. 6%). In addition, 4 silent mutations (except V399V) in exons and 8 variations in introns were found in this study.The IVS1nt + 40t→g and IVS10nt-31g→a were confirmed as novel variations by international PAH databases and IVS5nt-54g→a was the first report in China. Conclusion The frequencies of six common mutations were close to that in Beijing area of China, but it was different in sequence. The extensive mutation spectrum of the PAH gene showed higher heterogeneity in Tianjin and surrounding areas of Northern China comparing with other reports. According to this report, exons 7 and 11 are the hot spots and should be detected first for PAH gene quick diagnosis in this area, then comes exons 3, 6 and 12, and finally exons 5, 10 and others.

  4. Hydrodynamics of the Dirac spectrum

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Yizhuang, E-mail: yizhuang.liu@stonybrook.edu [Department of Physics and Astronomy, Stony Brook University, Stony Brook, NY 11794-3800 (United States); Warchoł, Piotr, E-mail: piotr.warchol@uj.edu.pl [M. Smoluchowski Institute of Physics, Jagiellonian University, PL-30348 Krakow (Poland); Zahed, Ismail, E-mail: ismail.zahed@stonybrook.edu [Department of Physics and Astronomy, Stony Brook University, Stony Brook, NY 11794-3800 (United States)

    2016-02-10

    We discuss a hydrodynamical description of the eigenvalues of the Dirac spectrum in even dimensions in the vacuum and in the large N (volume) limit. The linearized hydrodynamics supports sound waves. The hydrodynamical relaxation of the eigenvalues is captured by a hydrodynamical (tunneling) minimum configuration which follows from a pertinent form of Euler equation. The relaxation from a phase of unbroken chiral symmetry to a phase of broken chiral symmetry occurs over a time set by the speed of sound.

  5. Measurement of Hot Electron Spectrum

    Institute of Scientific and Technical Information of China (English)

    LIYe-jun; SHANYu-sheng; ZHANGHai-feng; ZHANGJi; WANGLei-jian; TANGXiu-zhang

    2003-01-01

    The hot electron spectrum was measured using 180°electron magnetic spectrometer through the irradiation of solid Cu target by an intense, near infrared(744 nm), P-polarized light, femtosecond (120 fs) laser pulse with free pre-pulse, and the intensity of laser is 1016 W/cm2 with 45° incidence. And the spectrometer was located in the direction of laser right reflection.

  6. ACE spectrum of LDPC codes

    Directory of Open Access Journals (Sweden)

    Vukobratović Dejan

    2006-01-01

    Full Text Available Construction of short-length LDPC codes with good, both waterfall and error-floor, behavior is still an attractive research problem. Recently proposed construction algorithms in this field are based on remarkably simple ideas, but yet, their effectiveness can still be questioned. In this paper we investigate a novel measure of goodness of a given LDPC code namely its ACE spectrum, based on a previously introduced ACE metrics associated with each cycle in LDPC code graph.

  7. Commutators with Finite Spectrum

    Institute of Scientific and Technical Information of China (English)

    Nadia BOUDI

    2009-01-01

    The purpose of this paper is to study derivations d, d' defined on a Banach algebra A such that the spectrum σ([dx, d'x]) is finite for all x ∈ A. In particular we show that if the algebra is semisimple, then there exists an element a in the socle of A such that [d, d'] is the inner derivation implemented by a.

  8. Baryon spectrum and chiral dynamics

    CERN Document Server

    Glozman, L Ya

    1995-01-01

    New results on baryon structure and spectrum developed in collaboration with Dan Riska [1-4] are reported. The main idea is that beyond the chiral symmetry spontaneous breaking scale light and strange baryons should be considered as systems of three constituent quarks with an effective confining interaction and a chiral interaction that is mediated by the octet of Goldstone bosons (pseudoscalar mesons) between the constituent quarks.

  9. Voice Collection under Different Spectrum

    Directory of Open Access Journals (Sweden)

    Min Li

    2013-05-01

    Full Text Available According to the short-time Fourier transform theory and principle of digital filtering, this paper established a mathematical model called collection of voice signal collection at different spectrum. The voice signal was a non-stationary process, while the standard Fourier transform only applied to the periodic signal, transient signals or stationary random signal. Therefore, the standard Fourier transform could not be directly used for the speech signal. By controlling the input different types and parameters, this paper analyzed the collected original voice signal spectrum with the use of MATLAB software platform. At the same time, it realized the extraction, recording and playback of the speech signal at different frequencies. Therefore, the waveforms could be displayed obviously on the graphic user interface and voice effect could be more clearly. Meanwhile, the result was verified by the hardware platforms, which consisted of TMS320VC5509A [1] chip and TLV320AIC23 voice chip. The results showed that the extraction of voice signal under different spectrum model was scientific, rational and effective.

  10. Audiological Findings in Patients with Oculo-Auriculo-Vertebral Spectrum

    Science.gov (United States)

    Sleifer, Pricila; Gorsky, Natalya de Souza; Goetze, Thayse Bienert; Rosa, Rafael Fabiano Machado; Zen, Paulo Ricardo Gazzola

    2014-01-01

    Introduction Oculo-auriculo-vertebral spectrum, also referred to as Goldenhar syndrome, is a condition characterized by alterations involving the development of the structures of the first and second branchial arches. The abnormalities primarily affect the face, the eyes, the spine, and the ears, and the auricular abnormalities are associated with possible hearing loss. Objective To analyze the audiological findings of patients with oculo-auriculo-vertebral spectrum through liminal pure-tone audiometry and speech audiometry test. Methods Cross-sectional study conducted on 10 patients with oculo-auriculo-vertebral spectrum and clinical findings on at least two of the following areas: orocraniofacial, ocular, auricular, and vertebral. All patients underwent tonal and vocal hearing evaluations. Results Seven patients were male and three were female; all had ear abnormalities, and the right side was the most often affected. Conductive hearing loss was the most common (found in 10 ears), followed by sensorineural hearing loss (in five ears), with mixed hearing loss in only one ear. The impairment of the hearing loss ranged from mild to moderate, with one case of profound loss. Conclusions The results show a higher frequency of conductive hearing loss among individuals with the oculo-auriculo-vertebral spectrum phenotype, especially moderate loss affecting the right side. Furthermore, research in auditory thresholds in the oculo-auriculo-vertebral spectrum is important in speech therapy findings about the disease to facilitate early intervention for possible alterations. PMID:25992144

  11. Reduced accuracy and sensitivity in the perception of emotional facial expressions in individuals with high autism spectrum traits

    NARCIS (Netherlands)

    Poljac, E.; Wagemans, J.P.

    2013-01-01

    Autism spectrum disorder (ASD) is among other things characterized by specific impairments in emotion processing. It is not clear, however, to what extent the typical decline in affective functioning is related to the specific autistic traits. We employed The Autism Spectrum-Quotient (AQ) to quantif

  12. Reduced Accuracy and Sensitivity in the Perception of Emotional Facial Expressions in Individuals with High Autism Spectrum Traits

    Science.gov (United States)

    Poljac, Ervin; Poljac, Edita; Wagemans, Johan

    2013-01-01

    Autism spectrum disorder (ASD) is among other things characterized by specific impairments in emotion processing. It is not clear, however, to what extent the typical decline in affective functioning is related to the specific autistic traits. We employed "The Autism Spectrum-Quotient" (AQ) to quantify autistic traits in a group of 500…

  13. [EMD Time-Frequency Analysis of Raman Spectrum and NIR].

    Science.gov (United States)

    Zhao, Xiao-yu; Fang, Yi-ming; Tan, Feng; Tong, Liang; Zhai, Zhe

    2016-02-01

    This paper analyzes the Raman spectrum and Near Infrared Spectrum (NIR) with time-frequency method. The empirical mode decomposition spectrum becomes intrinsic mode functions, which the proportion calculation reveals the Raman spectral energy is uniform distributed in each component, while the NIR's low order intrinsic mode functions only undertakes fewer primary spectroscopic effective information. Both the real spectrum and numerical experiments show that the empirical mode decomposition (EMD) regard Raman spectrum as the amplitude-modulated signal, which possessed with high frequency adsorption property; and EMD regards NIR as the frequency-modulated signal, which could be preferably realized high frequency narrow-band demodulation during first-order intrinsic mode functions. The first-order intrinsic mode functions Hilbert transform reveals that during the period of empirical mode decomposes Raman spectrum, modal aliasing happened. Through further analysis of corn leaf's NIR in time-frequency domain, after EMD, the first and second orders components of low energy are cut off, and reconstruct spectral signal by using the remaining intrinsic mode functions, the root-mean-square error is 1.001 1, and the correlation coefficient is 0.981 3, both of these two indexes indicated higher accuracy in re-construction; the decomposition trend term indicates the absorbency is ascending along with the decreasing to wave length in the near-infrared light wave band; and the Hilbert transform of characteristic modal component displays, 657 cm⁻¹ is the specific frequency by the corn leaf stress spectrum, which could be regarded as characteristic frequency for identification.

  14. Use of advanced magnetic resonance imaging techniques in neuromyelitis optica spectrum disorder

    NARCIS (Netherlands)

    S. Kremer (Stephane); F. Renard (Felix); S. Achard (Sophie); M.A. Lana-Peixoto (Marco A.); J. Palace (Jacqueline); N. Asgari (Nasrin); E.C. Klawiter (Eric C.); S. Tenembaum (Silvia); B. Banwell (Brenda); B.M. Greenberg (Benjamin M.); J.L. Bennett (Jeffrey); M. Levy (Michael); P. Villoslada (Pablo); A. Saiz (Albert Abe); K. Fujihara (Kazuo); K.H. Chan (Koon Ho); S. Schippling (Sven); F. Paul (Friedemann); H.J. Kim (Ho Jin); J. De Seze (Jerome); J.T. Wuerfel (Jens T.); P. Cabre (Philippe); R. Marignier (Romain); T. Tedder (Thomas); E.D. van Pelt - Gravesteijn (Daniëlle); S. Broadley (Simon); T. Chitnis (Tanuja); D. Wingerchuk (Dean); L. Pandit (Lekha); M.I. Leite (M. Isabel); M. Apiwattanakul (Metha); I. Kleiter (Ingo); N. Prayoonwiwat (Naraporn); M. Han (May); K. Hellwig (Kerstin); K. Van Herle (Katja); G. John (Gareth); D.C. Hooper (D. Craig); I. Nakashima (Ichiro); D. Sato (Douglas); M.R. Yeaman (Michael R.); E. Waubant (Emmanuelle); S. Zamvil (Scott); O. Stüve (Olaf); O. Aktas (Orhan); T.J. Smith (Terry J.); A. Jacob (Anu); K. O'Connor (Kevin)

    2015-01-01

    textabstractBrain parenchymal lesions are frequently observed on conventional magnetic resonance imaging (MRI) scans of patients with neuromyelitis optica (NMO) spectrum disorder, but the specific morphological and temporal patterns distinguishing them unequivocally from lesions caused by other diso

  15. Visual Scanning Patterns during the Dimensional Change Card Sorting Task in Children with Autism Spectrum Disorder

    Directory of Open Access Journals (Sweden)

    Li Yi

    2012-01-01

    Full Text Available Impaired cognitive flexibility in children with autism spectrum disorder (ASD has been reported in previous literature. The present study explored ASD children’s visual scanning patterns during the Dimensional Change Card Sorting (DCCS task using eye-tracking technique. ASD and typical developing (TD children completed the standardized DCCS procedure on the computer while their eye movements were tracked. Behavioral results confirmed previous findings on ASD children’s deficits in executive function. ASD children’s visual scanning patterns also showed some specific underlying processes in the DCCS task compared to TD children. For example, ASD children looked shorter at the correct card in the postswitch phase and spent longer time at blank areas than TD children did. ASD children did not show a bias to the color dimension as TD children did. The correlations between the behavioral performance and eye moments were also discussed.

  16. Autism Spectrum Disorder (ASD): Related Topics

    Science.gov (United States)

    ... Facebook Tweet Share Compartir Q: Do vaccines cause autism spectrum disorder (ASD)? A: Many studies that have ... whether there is a relationship between vaccines and autism spectrum disorder (ASD). To date, the studies continue ...

  17. Autism Spectrum Disorders (ASD) and Diet

    Science.gov (United States)

    ... For Toddler For Preschooler For Gradeschooler For Teen Autism Spectrum Disorders (ASD) and Diet Published April 01, 2016 Print Email nambitomo/iStock/Thinkstock Autism Spectrum Disorders, or ASD, is a complex developmental and neurological ...

  18. Hadron Structure and Spectrum from the Lattice

    CERN Document Server

    Lang, C B

    2015-01-01

    Lattice calculations for hadrons are now entering the domain of resonances and scattering, necessitating a better understanding of the observed discrete energy spectrum. This is a reviewing survey about recent lattice QCD results, with some emphasis on spectrum and scattering.

  19. Neutron spectrum unfolding: Pt. 1; Theoretical

    Energy Technology Data Exchange (ETDEWEB)

    Matiullah (Centre for Nuclear Studies, Nilore, Islamabad (Pakistan)); Wiyaja, D.S. (PPTN - BATAN, Bandung (Indonesia)); Berzonis, M.A.; Bondars, H.; Lapenas, A.A. (Latvijskij Gosudarstvennyj Univ., Riga (USSR)); Kudo, K. (Electrotechnical Lab., Tsukuba, Ibaraki (Japan)); Majeed, A.; Durrani, S.A. (Birimingham Univ. (United Kingdom). School of Physics and Space Research)

    1991-01-01

    The use of the latest PC version of the computer code SAIPS in neutron spectrum unfolding is described. Guidelines for extending the use of SAIPS to unfold the spectrum from a CR-39-based spectrometer are presented. (author).

  20. Smart Radio Spectrum Management for Cognitive Radio

    Directory of Open Access Journals (Sweden)

    Partha Pratim Bhattacharya

    2011-08-01

    Full Text Available Today’s wireless networks are characterized by fixed spectrum assignment policy. The limited availablespectrum and the inefficiency in the spectrum usage necessitate a new communication paradigm toexploit the existing wireless spectrum opportunistically. Cognitive radio is a paradigm for wirelesscommunication in which either a network or a wireless node changes its transmission or receptionparameters to communicate efficiently avoiding interference with licensed or unlicensed users. It cancapture best available spectrum to meet user communication requirements (spectrum management. Inthis work, a fuzzy logic based system for spectrum management is proposed where the radio can shareunused spectrum depending on parameters like distance, signal strength, node velocity and availabilityof unused spectrum. The system is simulated and is found to give satisfactory results.

  1. Spectrum-based kernel length estimation for Gaussian process classification.

    Science.gov (United States)

    Wang, Liang; Li, Chuan

    2014-06-01

    Recent studies have shown that Gaussian process (GP) classification, a discriminative supervised learning approach, has achieved competitive performance in real applications compared with most state-of-the-art supervised learning methods. However, the problem of automatic model selection in GP classification, involving the kernel function form and the corresponding parameter values (which are unknown in advance), remains a challenge. To make GP classification a more practical tool, this paper presents a novel spectrum analysis-based approach for model selection by refining the GP kernel function to match the given input data. Specifically, we target the problem of GP kernel length scale estimation. Spectrums are first calculated analytically from the kernel function itself using the autocorrelation theorem as well as being estimated numerically from the training data themselves. Then, the kernel length scale is automatically estimated by equating the two spectrum values, i.e., the kernel function spectrum equals to the estimated training data spectrum. Compared with the classical Bayesian method for kernel length scale estimation via maximizing the marginal likelihood (which is time consuming and could suffer from multiple local optima), extensive experimental results on various data sets show that our proposed method is both efficient and accurate.

  2. Short range spread-spectrum radiolocation system and method

    Science.gov (United States)

    Smith, Stephen F.

    2003-04-29

    A short range radiolocation system and associated methods that allow the location of an item, such as equipment, containers, pallets, vehicles, or personnel, within a defined area. A small, battery powered, self-contained tag is provided to an item to be located. The tag includes a spread-spectrum transmitter that transmits a spread-spectrum code and identification information. A plurality of receivers positioned about the area receive signals from a transmitting tag. The position of the tag, and hence the item, is located by triangulation. The system employs three different ranging techniques for providing coarse, intermediate, and fine spatial position resolution. Coarse positioning information is provided by use of direct-sequence code phase transmitted as a spread-spectrum signal. Intermediate positioning information is provided by the use of a difference signal transmitted with the direct-sequence spread-spectrum code. Fine positioning information is provided by use of carrier phase measurements. An algorithm is employed to combine the three data sets to provide accurate location measurements.

  3. Electrical spectrum & network analyzers a practical approach

    CERN Document Server

    Helfrick, Albert D

    1991-01-01

    This book presents fundamentals and the latest techniques of electrical spectrum analysis. It focuses on instruments and techniques used on spectrum and network analysis, rather than theory. The book covers the use of spectrum analyzers, tracking generators, and network analyzers. Filled with practical examples, the book presents techniques that are widely used in signal processing and communications applications, yet are difficult to find in most literature.Key Features* Presents numerous practical examples, including actual spectrum analyzer circuits* Instruction on how to us

  4. Auction design for the wireless spectrum market

    CERN Document Server

    Lin, Peng; Zhang, Qian

    2014-01-01

    This Brief introduces the wireless spectrum market and discusses the current research for spectrum auctions. It covers the unique properties of spectrum auction, such as interference relationship, reusability, divisibility, composite effect and marginal effect, while also proposing how to build economic incentives into the network architecture and protocols in order to optimize the efficiency of wireless systems.Three scenarios for designing new auctions are demonstrated. First, a truthful double auction scheme for spectrum trading considering both the heterogeneous propagation properties of c

  5. Direct sequence spread spectrum CDMA in shared spectrum applications

    Science.gov (United States)

    Schilling, Donald L.; Milstein, Laurence B.; Pickholtz, Raymond L.; Miller, Frank

    1991-01-01

    Personal Communication Network (PCN) is an entirely wireless communication system with the capability of assessing the wired telephone system to reach anyone processing only a wired telephone. It is expected to compete with the existing mobile cellular system which connects directly to the wired telephone system. While many PCN systems employ TDMA technology, the PCN system described here uses Broadband CDMA (BCDMA(sup SM)) which is capable of sharing the spectrum with other users and which is extremely resistant to fading caused by multipath.

  6. Revitalization Areas

    Data.gov (United States)

    Department of Housing and Urban Development — Revitalization areas are HUD-designated neighborhoods in need of economic and community development and where there is already a strong commitment by the local...

  7. Wooded areas

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes the management of wooded areas on Neal Smith National Wildlife Refuge (formerly Walnut Creek National Wildlife Refuge) between 1992 and 2009.

  8. 700 Area

    Data.gov (United States)

    Federal Laboratory Consortium — The 700 Area of the Hanford Site is located in downtown Richland.Called the Federal Office Building, the Richland Operations Site Manager and the Richland Operations...

  9. Specific phobias.

    Science.gov (United States)

    Hamm, Alfons O

    2009-09-01

    Exposure based treatments in which patients are systematically confronted with their feared objects of situations are highly effective in the treatment of specific phobias and produce stable improvement both in reported fear and behavioral avoidance. Exposure in reality is more effective in most cases than exposure in sensu. For situations that are difficult to realize, exposure in virtual environments has become increasingly valuable. Exposure in vivo is clearly superior to pharmacotherapy, although cognitive enhancers have been successfully used recently to increase the effect of exposure therapy. The induction of relaxation is not a necessary precondition for exposure therapy. Rather the current mechanisms of change focus on extinction learning as being the central mechanism both on a cognitive level namely that the feared object is no longer associated with severely threatening consequence but also on an affective level, meaning that feared cue is no longer capable to activate the fear circuit in the brain. Accordingly future diagnostic categorizations of phobic disorders in the DSM-V should rather focus on the pattern of the fear response that needs to be changed than on the eliciting cues or situations that are avoided.

  10. Prenatal Antidepressants and Autism Spectrum Disorder

    Science.gov (United States)

    2014-09-01

    Autism Spectrum Disorder PRINCIPAL INVESTIGATOR...TYPE Annual 3. DATES COVERED 1Sept 2013-31Aug2014 4. TITLE AND SUBTITLE Prenatal Antidepressants and Autism Spectrum Disorder 5a...Approved for Public Release; Distribution Unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT According to the CDC Autism Spectrum Disorder

  11. The end of the Galactic spectrum

    CERN Document Server

    De Donato, C

    2007-01-01

    We use a diffusion galactic model to analyze the end of the Galactic cosmic ray spectrum and its mixing with the extragalactic cosmic ray flux. We analyze the transition between Galactic and extragalactic components using two different extragalactic models. We compare the sum of the diffusive galactic spectrum and extragalactic spectrum with the available experimental data.

  12. Fetal Alcohol Spectrum Disorders: an overview from the glia perspective

    Directory of Open Access Journals (Sweden)

    Clare J. Wilhelm

    2016-01-01

    Full Text Available Alcohol consumption during pregnancy can produce a variety of central nervous system abnormalities in the offspring resulting in a broad spectrum of cognitive and behavioral impairments that constitute the most severe and long-lasting effects observed in fetal alcohol spectrum disorders (FASD. Alcohol-induced abnormalities in glial cells have been suspected of contributing to the adverse effects of alcohol on the developing brain for several years, although much research still needs to be done to causally link the effects of alcohol on specific brain structures and behavior to alterations in glial cell development and function. Damage to radial glia due to prenatal alcohol exposure may underlie observations of abnormal neuronal and glial migration in humans with Fetal Alcohol Syndrome (FAS, as well as primate and rodent models of FAS. A reduction in cell number and altered development has been reported for several glial cell types in animal models of FAS. In utero alcohol exposure can cause microencephaly when alcohol exposure occurs during the brain growth spurt a period characterized by rapid astrocyte proliferation and maturation; since astrocytes are the most abundant cells in the brain, microenchephaly may be caused by reduced astrocyte proliferation or survival, as observed in in vitro and in vivo studies. Delayed oligodendrocyte development and increased oligodendrocyte precursor apoptosis has also been reported in experimental models of FASD, which may be linked to altered myelination/white matter integrity found in FASD children. Children with FAS exhibit hypoplasia of the corpus callosum and anterior commissure, two areas requiring guidance from glial cells and proper maturation of oligodendrocytes. Finally, developmental alcohol exposure disrupts microglial function and induces microglial apoptosis; given the role of microglia in synaptic pruning during brain development, the effects of alcohol on microglia may be involved in the

  13. Spectrum and service pricing for 802.22 networks

    DEFF Research Database (Denmark)

    Stefan, Andrei Lucian; Rota, Cyril; Pratas, Nuno

    2011-01-01

    of channels which have an impact on the demand, and thus on the spectrum pricing. The second part of the paper exemplifies how a Bertrand game model can solve the issue of service pricing for a Wireless Regional Area Network (WRAN) operator that is trying to deploy an 802.22 network in a region where...... a competitor already exists. In this work the service pricing was envisioned as a network preplanning step, one that would show the potential revenues for an operator by entering as inputs, among other, the competitor's coverage area and spectrum pricing. The case study has been conducted through CNPT1......, an ongoing cognitive radio network planning tool developed by the authors....

  14. Microwave spectrum of 1-bromobutane

    Science.gov (United States)

    Kim, Jihyun; Jang, Heesu; Ka, Soohyun; Obenchain, Daniel A.; Peebles, Rebecca A.; Peebles, Sean A.; Oh, Jung Jin

    2016-10-01

    The rotational spectrum of 1-bromobutane has been measured in the range of 8-18 GHz using a 480 MHz bandwidth chirped-pulse Fourier transform microwave (CP-FTMW) spectrometer. 1-bromobutane has five conformers; aa, ag, ga, gg, gg‧. Spectra for the 79Br isotopic species and 81Br isotopic species were observed and assigned for the three lowest energy conformers, aa, ga, and gg. Consequentially, the rotational constants, nuclear quadrupole coupling constants, and centrifugal distortion constants were determined and the dipole moment of the aa conformer with 79Br was measured. All the experimental data are in good agreement with the ab initio calculations.

  15. Heavy hadron spectrum and interactions

    CERN Document Server

    Ebert, D

    1996-01-01

    Starting from the approximate symmetries of QCD, namely chiral symmetry for light quarks and spin and flavor symmetry for heavy quarks, we investigate the low-energy properties of heavy hadrons. For this purpose we construct a consistent picture of quark-antiquark and quark-diquark interactions as a low-energy approximation to the flavor dynamics in heavy mesons and heavy baryons, respectively. Using standard functional integration tools, we derive an effective Lagrangian in terms of heavy hadron fields and discuss several properties, like the mass spectrum, coupling and decay constants, Isgur-Wise form factors.

  16. Hydro/Engineering Geophysical Parameters and Design Response Spectrum for Sustainable Development in Ras Muhammed National Park, Sinai

    Science.gov (United States)

    Khalil, Mohamed H.; Gamal, Mohamed A.

    2016-06-01

    The Egyptian government is preparing a sustainable development master plan for the Ras Muhammed National Park (RMNP), south Sinai. Noteworthy, the scarcity of the freshwater resources and close proximity to the active seismic zones of the Gulf of Aqaba implicate geophysical investigations for the fresh groundwater aquifers and construct a design response spectrum, respectively. Accordingly, 14 VESs, hydro/engineering geophysical analysis, pumping tests, downhole seismic test, a design response spectrum for buildings, and borehole data were carried out in the study area. The unconfined freshwater aquifer was effectively depicted with true resistivities, thickness, and EC ranged from 56 to 135 Ω m, 11 to 112 m, and 1.4 to 7.1 mS/m, respectively. The Northeastern part was characterized by higher aquifer potentiality, where coarser grains size, highest thickness (112 m), high true resistivity (135 Ω m), groundwater flow (0.074 m3/day), tortuosity (1.293-1.312), formation resistivity factor (4.1-4.6), and storativity (0.281-0.276). An increase in pumping rate was accompanied by an increase in well loss, increase in aquifer losses, decrease in well specific capacity, and decrease in well efficiency. Design response spectrum prognosticated the short buildings (<7 floors) in RMNP to be suffering from a high peak horizontal acceleration and shear forces for acceleration between 0.25 and 0.35 g. Therefore, appropriate detailing of shear reinforcement is indispensable to reduce the risk of structural damages at RMNP.

  17. Spectrum correction algorithm for detectors in airborne radioactivity monitoring equipment NH-UAV based on a ratio processing method

    Energy Technology Data Exchange (ETDEWEB)

    Cao, Ye [Department of Nuclear Science and Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016 (China); Tang, Xiao-Bin, E-mail: tangxiaobin@nuaa.edu.cn [Department of Nuclear Science and Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016 (China); Jiangsu Key Laboratory of Nuclear Energy Equipment Materials Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016 (China); Wang, Peng; Meng, Jia; Huang, Xi; Wen, Liang-Sheng [Department of Nuclear Science and Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016 (China); Chen, Da [Department of Nuclear Science and Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016 (China); Jiangsu Key Laboratory of Nuclear Energy Equipment Materials Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016 (China)

    2015-10-11

    The unmanned aerial vehicle (UAV) radiation monitoring method plays an important role in nuclear accidents emergency. In this research, a spectrum correction algorithm about the UAV airborne radioactivity monitoring equipment NH-UAV was studied to measure the radioactive nuclides within a small area in real time and in a fixed place. The simulation spectra of the high-purity germanium (HPGe) detector and the lanthanum bromide (LaBr{sub 3}) detector in the equipment were obtained using the Monte Carlo technique. Spectrum correction coefficients were calculated after performing ratio processing techniques about the net peak areas between the double detectors on the detection spectrum of the LaBr{sub 3} detector according to the accuracy of the detection spectrum of the HPGe detector. The relationship between the spectrum correction coefficient and the size of the source term was also investigated. A good linear relation exists between the spectrum correction coefficient and the corresponding energy (R{sup 2}=0.9765). The maximum relative deviation from the real condition reduced from 1.65 to 0.035. The spectrum correction method was verified as feasible. - Highlights: • An airborne radioactivity monitoring equipment NH-UAV was developed to measure radionuclide after a nuclear accident. • A spectrum correction algorithm was proposed to obtain precise information on the detected radioactivity within a small area. • The spectrum correction method was verified as feasible. • The corresponding spectrum correction coefficients increase first and then stay constant.

  18. Spectrum of phylalanine hydroxylase gene mutations and genotype-phenotype correlation in the patients with phenylketonuria in Beijing area of China%北京地区苯丙酮尿症基因突变构成及基因型与表型相关分析

    Institute of Scientific and Technical Information of China (English)

    瞿宇晋; 宋昉; 金煜炜; 王红; 张玉敏; 秦金莉; 裘蕾

    2008-01-01

    Objective To identify the mutation spectrum and the distribution of minihaplotypes (STR/VNTR)of phenylalanine hydroxylase(PAH)gene and explore the C01Te]ations between genotype and phenotype of patients with phenylketonuria(PKU)in Beijing area of China.Method (1)Fifty cases with PKU were involved in this study.PKU was identified by the Neonatal Screening Center of Beijing.All 13 exons and their flanking intronic sequences of PAH gene of these patients were amplified and then subjected to SSCP analysis and direct sequencing.(2)The distribution of polymorphic locus of short tandem repeat (STR)and variable number tandem repeat(VNTR)was analyzed by PCR and denaturing gel electrophoresis.(3)The correlations between genotype and phenotype were studied by analysis of the matching rate between the expected and observed phenotypes.The predicted phenotype was determined on the basis of the sum of the assigned values of the two mutant alleles.Results (1)A total of 34 different mutations were detected with the relative frequency of 95% among 50 PKU patients.The prevalent mutations in this study were:R243Q(20%),EX6-96A>G(11%),Y356X(9%),and V399V(7%).The next common mutations were R111X(5%),R413P(5%),R252Q(3%)and A434D(3%).Thirty-four detected mutations were distributed throughout the whole PAH gene,except exon 1,8 and 13.Exon 7 and 11,with the mutant rate 34% and 19% respectively,seemed to be the hot mutant areas/regions of PAH gene.(2)The minihaplotypes(STR/VNTR)of 34 mutations were identified in this research.The STR and VNTR showed 8 and 3 alleles,respectively.Among them,244 bp(44%)and 240 bp(34%)were the prevalent STR alleles.Meanwhile,the VNTR3(83%)was the most common VNTR allele in PKU patients.(3)A better consistency(81.5%)between expected and observed phenotypes was revealed by analysis of correlation between genotype and phenotype.Especially in classic PKU,the consistency rate was up to 87.5%.Conclusion(1)The frequency distribution of common PAH gene mutations in

  19. Gluten- and casein-free dietary intervention for autism spectrum conditions.

    Directory of Open Access Journals (Sweden)

    Paul eWhiteley

    2013-01-01

    Full Text Available Dietary intervention as a tool for maintaining and improving physical health and wellbeing is a widely researched and discussed topic. Speculation that diet may similarly affect mental health and wellbeing particularly in cases of psychiatric and behavioural symptomatology opens up various avenues for potentially improving quality of life. We examine evidence suggestive that a gluten-free, casein-free or combined gluten- and casein-free diet can ameliorate core and peripheral symptoms and improve developmental outcome in some cases of autism spectrum conditions. Although not wholly affirmative, the majority of published studies indicate statistically significant positive changes to symptom presentation following dietary intervention. In particular, changes to areas of communication, attention and hyperactivity are detailed, despite the presence of various methodological shortcomings. Specific characteristics of best- and non-responders to intervention have not been fully elucidated; neither has the precise mode of action for any universal effect outside of known individual cases of food-related co-morbidity. With the publication of controlled medium- and long-term group studies of a gluten- and casein-free diet alongside more consolidated biological findings potentially linked to intervention, the appearance of a possible diet-related autism phenotype seems to be emerging supportive of a positive dietary effect in some cases. Further debate on whether such dietary intervention should form part of best practice guidelines for autism spectrum conditions and onward representative of an autism dietary-sensitive enteropathy is warranted.

  20. The Spectrum of Renal Allograft Failure

    Science.gov (United States)

    Chand, Sourabh; Atkinson, David; Collins, Clare; Briggs, David; Ball, Simon; Sharif, Adnan; Skordilis, Kassiani; Vydianath, Bindu; Neil, Desley; Borrows, Richard

    2016-01-01

    Background Causes of “true” late kidney allograft failure remain unclear as study selection bias and limited follow-up risk incomplete representation of the spectrum. Methods We evaluated all unselected graft failures from 2008–2014 (n = 171; 0–36 years post-transplantation) by contemporary classification of indication biopsies “proximate” to failure, DSA assessment, clinical and biochemical data. Results The spectrum of graft failure changed markedly depending on the timing of allograft failure. Failures within the first year were most commonly attributed to technical failure, acute rejection (with T-cell mediated rejection [TCMR] dominating antibody-mediated rejection [ABMR]). Failures beyond a year were increasingly dominated by ABMR and ‘interstitial fibrosis with tubular atrophy’ without rejection, infection or recurrent disease (“IFTA”). Cases of IFTA associated with inflammation in non-scarred areas (compared with no inflammation or inflammation solely within scarred regions) were more commonly associated with episodes of prior rejection, late rejection and nonadherence, pointing to an alloimmune aetiology. Nonadherence and late rejection were common in ABMR and TCMR, particularly Acute Active ABMR. Acute Active ABMR and nonadherence were associated with younger age, faster functional decline, and less hyalinosis on biopsy. Chronic and Chronic Active ABMR were more commonly associated with Class II DSA. C1q-binding DSA, detected in 33% of ABMR episodes, were associated with shorter time to graft failure. Most non-biopsied patients were DSA-negative (16/21; 76.1%). Finally, twelve losses to recurrent disease were seen (16%). Conclusion This data from an unselected population identifies IFTA alongside ABMR as a very important cause of true late graft failure, with nonadherence-associated TCMR as a phenomenon in some patients. It highlights clinical and immunological characteristics of ABMR subgroups, and should inform clinical practice and