Sample records for arabinonucleotides

  1. Cyclization of nucleotide analogues as an obstacle to polymerization (United States)

    Hill, A. R. Jr; Nord, L. D.; Orgel, L. E.; Robins, R. K.


    Cyclization of activated nucleotide analogues by intramolecular phosphodiester-bond formation is likely to compete very effectively with template-directed condensation except in the cases of ribo- and arabinonucleotides. This could have excluded derivatives of most sugars from growing polyribonucleotide chains and thus reduced chain-termination in prebiotic polynucleotide synthesis.