WorldWideScience

Sample records for apres traitement conservateur

  1. Oncoplastie avec conservation mammaire dans le traitement du cancer du sein: à propos de 16 cas

    Science.gov (United States)

    Bouzoubaa, Wail; Laadioui, Meryam; Jayi, Sofia; Alaoui, Fatime Zahra Fdili; Bouguern, Hakima; Chaara, Hikmat; Melhouf, Moulay Abdelilah

    2015-01-01

    Le cancer du sein est actuellement le cancer le plus fréquent chez la femme, et pose un véritable problème diagnostique et thérapeutique. Le dépistage des lésions à un stade de plus en plus précoce, a permis une extension des indications du traitement conservateur radiochirurgical, qui était initialement limitées aux tumeurs de moins de 3 cm, unifocales, non inflammatoires. Par ailleurs, l'utilisation de traitements préopératoires permet d’étendre les indications du traitement conservateur à des tumeurs plus volumineuses. Parallèlement à cette extension des indications de conservation mammaire, on a observé le développement de nouvelles approches thérapeutiques notamment la chirurgie oncoplastique, technique du ganglion sentinelle et chirurgie stéréotaxique, dont les résultats initiaux sont très encouragent. A travers cette étude réalisée dans le service de gynécologie et obstétrique II du CHU HASSAN II de FES au MAROC, après l'analyse rétrospective de 16 patientes traitées par traitement conservateur et oncoplastie, nous avons voulus montrer notre aptitude a réalisé ses techniques chirurgicales et a bien prendre en charge ces patientes, mais aussi évaluer ces techniques en termes de résultat carcinologique et de résultat esthétique, aussi en terme de survie globale, survie sans métastase et en termes de récidive locale entre les plasties mammaires et les traitements usuels: mastectomie et traitement conservateur classique. PMID:26430477

  2. Re-irradiation after salvage mastectomy for local recurrence after a conservative treatment: a retrospective analysis of twenty patients (Nancy: 1988-2001); Re-irradiation parietale apres mastectomie de rattrapage pour recidive d'un cancer du sein apres traitement conservateur: etude retrospective sur 20 patientes (Nancy: 1988-2001)

    Energy Technology Data Exchange (ETDEWEB)

    Racadot, S.; Marchal, C.; Charra-Brunaud, C.; Peiffert, D.; Bey, P. [Centre Alexis-Vautrin, Service de Radiotherapie, 54 - Vandoeuvre-les-Nancy (France); Verhaeghe, J.L. [Centre Alexis-Vautrin, Service de Chirurgie, 54 - Vandoeuvre-les-Nancy (France)

    2003-12-01

    Purpose. - To retrospectively assess the efficacy of post-mastectomy re-irradiation for local relapse of breast cancer. Patients and methods. - Twenty patients, initially treated by conservative surgery and radiotherapy (50 Gy in 25 fractions over 5 weeks) were treated from 1998 to 2001 for a local relapse by salvage mastectomy and re-irradiation (either electron or photon beams). Mean age was 53 years (31-71). Reasons for re-irradiation were that the local relapses were inflammatory (4 pts), multifocal (5 pts), cutaneous (5 pts), involved the nipple (3 pts) or because the surgical margins (either muscle or skin) were involved (3 pts). The median dose of re-irradiation was 45 Gy (33-65) in 15 fractions over 33 days. Mean follow-up was 48 months (5-97). Results. - Fifteen patients remained free of a second local recurrence and 10 were still alive, without metastasis. Neither the dose of re-irradiation nor the irradiated surfaces were prognostic factors of local control (P = 0.877 and P = 0.424). Five patients developed radiation-induced pneumonitis without functional respiratory impairment. The incidence of pneumonitis seemed to be related to the biological dose of re-irradiation (P = 0.037). Other late complications occurred such as pigmentation changes (12 pts), telangiectasia (8 pts), chondritis (2 pts), parietal fibrosis (7 pts), rib fractures (4 pts), severe pain (11 pts) and lymphedema (2 pts). The increase in biological equivalent dose was highly statistically linked with the occurrence of disabling pain (P = 0.0123). Conclusion. - Parietal re-irradiation achieves good and lasting local control with an acceptable rate of acute complications but with a risk of disabling late sequelae such as severe pain. (author)

  3. Is it always possible to respect dose constraints for target volumes and organs at risk within the frame of breast radiotherapy after conservative treatment?; Le respect des contraintes de dose aux volumes cibles et aux organes a risque est-il toujours possible dans le cadre d'une radiotherapie du sein apres traitement conservateur?

    Energy Technology Data Exchange (ETDEWEB)

    Renoult, F.; Faivre, J.C.; Charra Brunaud, C.; Tournier-Rangeard, L.; Lostette, J.; Huger, S.; Marchesi, V.; Peiffert, D.; Marchal, C. [Centre Alexis-Vautrin, 54 - Nancy (France); Xemard, S. [Centre hospitalier Jean-Monnet, 88 - Epinal (France)

    2010-10-15

    The use of three-dimensional breast radiotherapy after a conservative treatment allowed cardiotoxicity as well as the dose delivered to lungs to be significantly reduced. However several bibliographic references give different dose constraints. Based on the constraints given by the Oncological radiotherapy French Society (SFRO), the authors analysed whether these recommendations could be actually respected within a daily practice. Based on a sample of 91 patients, the authors collected the following data: mammary gland volumes receiving respectively 95 and 107% of the dose before the boost calculation, heart and pulmonary volumes receiving different dose levels. Coverage constraints are indicated. It appears that the present technique does not allow the constraints to be respected in a majority of cases. Short communication

  4. Le tournant conservateur au Canada et le nouveau nation-building canadien

    OpenAIRE

    Ipperciel, Donald

    2015-01-01

    Cet article défend la thèse selon laquelle le tournant conservateur de Harper doit être compris moins en termes hayékiens que comme un désir de redéfinir la « philosophie publique » du Canada dans le sens du toryisme canadien. Les conservateurs chercheraient à repenser ce qu’on appelle communément les « valeurs canadiennes » et l’identité canadienne, que les Libéraux ont pu façonner à leur guise au cours d’un demi-siècle, et de réorienter l’identité nationale vers des principes conservateurs ...

  5. Infiltration de concentré plaquettaire dans le traitement des tendinopathies rotuliennes : résultats préliminaires

    OpenAIRE

    Kaux, Jean-François; Croisier, Jean-Louis; Simoni, Paolo; Lonneux, Vincent; Laparaille, Stuart; Brabant, Gautier; Noël, David; Rodriguez de la Cruz, Carlos; Daniel, Christophe; Collette, Julien; Gothot, André; Le Goff, Caroline; Crielaard, Jean-Michel

    2011-01-01

    Introduction : L’évolution de certaines tendinopathies, et plus particulièrement, les tendinopathies rotuliennes aussi appelées Jumper’s knee demeurent relativement rebelles aux traitements «conservateurs». Divers travaux expérimentaux ont souligné les propriétés réparatrices des plaquettes et de divers facteurs de croissances libérés localement. Ceux-ci peuvent effectivement accélérer la cicatrisation de certains tissus : os, muscles et tendons. Ces recherches ont permis de comprendre l’acti...

  6. Entropy in Signal Processing (Entropie en Traitement du Signal)

    OpenAIRE

    Mohammad-Djafari, Ali

    2001-01-01

    R\\'esum\\'e: Le principal objet de cette communication est de faire une r\\'etro perspective succincte de l'utilisation de l'entropie et du principe du maximum d'entropie dans le domaine du traitement du signal. Apr\\`es un bref rappel de quelques d\\'efinitions et du principe du maximum d'entropie, nous verrons successivement comment l'entropie est utilis\\'ee en s\\'eparation de sources, en mod\\'elisation de signaux, en analyse spectrale et pour la r\\'esolution des probl\\`emes inverses lin\\'eaire...

  7. Les clarifloculateurs plus particulièrement utilisés en traitement tertiaire

    OpenAIRE

    Canler, J.P.; Perret, J.M.

    2007-01-01

    / Pour répondre aux niveaux d'exigence de qualité des rejets en sortie de station d'épuration sur le phosphore et la matière organique, des traitements complémentaires sont implantés à l'aval de l'étage de traitement biologique secondaire. Parmi les différentes technologies disponibles en traitement tertiaire, le clari-floculateur, basé sur un traitement physico-chimique, est un des procédés récemment développés. Après un rappel sur l'évolution des différents composés au sein d'une filière d...

  8. Conservative treatment for invasive bladder cancer: neo-adjuvant chemotherapy and radiotherapy; Traitement conservateur des cancers infiltrants de la vessie: chimiotherapie neoadjuvante et radiotherapie

    Energy Technology Data Exchange (ETDEWEB)

    Prie, L.; Gaston, R.; Richaud, P.; Brui, B.N. [Institut Bergonie, Centre Regional de Lutte Contre le Cancer, 33 - Bordeaux (France); Ferriere, J.M.; Le Guillou, M. [Hopital Pellegrin, 33 - Bordeaux (France)

    1998-04-01

    Retrospective evaluation of tolerance and efficiency of a combination of chemotherapy and radiotherapy in non metastatic invasive cancer of the bladder. Neo-adjuvant chemotherapy leads to CR in 44 % of patients and CR is observed in 64 % of the patients after radiation therapy. However, the survival rate at 5 years is insufficient, even if the rate of bladder conservation is high. (author)

  9. Second conservative radiosurgical treatment for ipsilateral breast cancer recurrence; Second traitement conservateur radiochirurgical dans les recidives locales du cancer du sein

    Energy Technology Data Exchange (ETDEWEB)

    Castelli, J.; Courdi, A.; Hannoun-Levi, J.M. [Departement de radiotherapie oncologique, centre Antoine-Lacassagne, 33, avenue de Valombrose, 06189 Nice cedex (France); Figl, A.; Raoust, I.; Lallement, M.; Flipo, B. [Departement de chirurgie mammaire, centre Antoine-Lacassagne, 33, avenue de Valombrose, 06189 Nice cedex (France); Ettore, F. [Departement d' anatomopathologie, centre Antoine-Lacassagne, 33, avenue de Valombrose, 06189 Nice cedex (France); Chapelier, C. [Departement de radiologie, centre Antoine-Lacassagne, 33, avenue de Valombrose, 06189 Nice cedex (France); Ferrero, J.M. [Departement d' oncologie medicale, centre Antoine-Lacassagne, 33, avenue de Valombrose, 06189 Nice cedex (France)

    2011-04-15

    Purpose. - Currently, radical mastectomy represents the gold standard for ipsilateral breast cancer recurrence. However, we already showed that a second conservative treatment was feasible combining lumpectomy plus low-dose rate interstitial brachytherapy. In this study, we reported the preliminary results of a second conservative treatment using a high-dose rate brachytherapy. Patients and methods. - From June 2005 to July 2009, 42 patients presenting with an ipsilateral breast cancer recurrence underwent a second conservative treatment. Plastic tubes were implanted intraoperatively at the time of the lumpectomy. After a post-implant CT scan, a total dose of 34 Gy in 10 fractions over 5 consecutive days was delivered through an ambulatory procedure. The toxicity evaluation used the Common Terminology Criteria for Adverse Events v3.0. Results. - The median follow-up was 21 months (6-50 months), median age at the time of the local recurrence was 65 years (30-85 years). The median delay between the primary and the recurrence was 11 years (1-35 years). The location of the recurrence was in the tumor bed for 22 patients (52.4%), in the same quadrant for 14 patients (33.3%) and unknown for six patients (14.3%). The median tumor size of the recurrence was 12 mm (2-30 mm). The median number of plastic tubes and plans were nine (5-12) and two (1-3) respectively. The median CTV was 68 cm{sup 3} (31.2-146 cm{sup 3}). The rate of second local control was 97%. Twenty-two patients (60%) experienced complications. The most frequent side effect consisted in cutaneous and sub-cutaneous fibrosis (72% of all the observed complications). Conclusion. - A second conservative treatment for ipsilateral breast cancer recurrence using high-dose rate brachytherapy appears feasible leading to encouraging results in terms of second local control with an acceptable toxicity. Considering that a non-inferiority randomized trial comparing mastectomy versus second conservative treatment could be difficult to perform, what proof level will be necessary to achieve in order to change the medical procedures? (authors)

  10. Processus de traitement de l'air t.1

    CERN Document Server

    Edipa

    2009-01-01

    Edition entièrement revue et actualisée du tome 1 de « L'intégrale de la Clim », consacré aux processus de traitement de l'air. Cet ouvrage qui comprend 224 pages (au lieu de 166 lors de la précédente édition), aborde d'une façon très pratique toutes les techniques mises en oeuvre pour traiter les caractéristiques physiques de l'air en fonction de la qualité de l'ambiance recherchée : habitat, locaux tertiaires, locaux industriels, salles propres, salles de spectacles, piscines, etc. Dans un premier temps sont présentées les propriétés physiques de l'air humide et l'ensemble de ses caractéristiques. Après avoir analysé les fonctions que l'on souhaite réaliser, le système aéraulique est choisi et les différents débits d'air sont calculés. Chaque traitement élémentaire (chauffage, refroidissement, humidification, déshumidification, filtration, atténuation acoustique, récupération de chaleur, etc.) est ensuite étudié. Les procédés de régulation sont aussi examinés. Un nouve...

  11. (E)TUDE DE ENC(E)PHALE ATLAS DANS PR(E) - TRAITEMENT ET POST- TRAITEMENT DE MALADIE C(E)R(E)BROVASCULAIRE ISCH(E)MIQUE PAR "PIAN TAN NING"

    Institute of Scientific and Technical Information of China (English)

    LIU Mingshun; WU Xinman; HAN Ying; GU Langjie; LIU Qingrui

    2003-01-01

    Objectif: De explorer valeure appliquée de encéphale atlas dans évaluation de effet curatif de maladie cérébrovasculaire ischémique. Méthode: Etude comparative de encéphale atlas de 300 malades avec maladie cérébrovasculaire ischémique avant et après traitement est réalisé. Résultat:Encéphale atlas est changé manifestement avant et après traitement. Conclusion: Encéplale atlas est un index valable de jugement de effet curatif dans maladie cérébrovasculaire ischémique.

  12. Traitement automatique du langage naturel

    OpenAIRE

    BADREDDINE, I

    2011-01-01

    Cette étude s'intéresse particulièrement aux exigences de sécurité et à une méthode d'extraction des exigences. Pour cette extraction, nous nous sommes penchés sur le traitement automatique du langage naturel. Une discipline, à la frontière de la linguistique, de l'informatique et de l'intelligence artificielle, qui concerne l'application de programme informatique à tous les aspects du langage humain (écrit et/ou parlé). Le but de l'étude du TALN est d'explorer les méthodes et de connaître la...

  13. Outil d'aide au choix de filières de traitement d'eaux résiduaires industrielles

    OpenAIRE

    Laforest, Valérie; Muret, Carole; Bourgois, Jacques

    2010-01-01

    Cette étude contribue au choix automatique de filières de traitement d'eaux résiduaires industrielles après obtention de leur spectre UV. Les filières prises en compte sont les suivantes : procédés d'oxydation avancée (H2O2/UV), traitement biologique, coagulation/floculation/filtration, adsorption sur charbon actif ou méthodes de destruction comme l'évapo-incinération. Un traitement mathématique des spectres UV permet la détermination de plusieurs paramètres conduisant au choix de filières pa...

  14. Traitement antihypertenseur : quelles sont les meilleures associations?

    OpenAIRE

    Krzesinski, Jean-Marie

    2014-01-01

    Stratégie du traitement de l’HTA en 2014: toujours basée sur le calcul du risque CV. L’HTA, tueur silencieux, est généralement associée à de nombreux autres facteurs de risque CV. Il faut préciser le niveau de risque CV en tenant compte de la valeur de PA et des autres F.R. pour décider le moment et le type de traitement !

  15. APR-2 Tropical Cyclone Observations

    Science.gov (United States)

    Durden, S. L.; Tanelli, S.

    2011-01-01

    The Second Generation Airborne Precipitation Radar (APR-2) participated in the Genesis and Rapid Intensification Processes (GRIP) experiment in August and September of 2010, collecting a large volume of data in several tropical systems, including Hurricanes Earl and Karl. Additional measurements of tropical cyclone have been made by APR-2 in experiments prior to GRIP (namely, CAMEX-4, NAMMA, TC4); Table 1 lists all the APR-2 tropical cyclone observations. The APR-2 observations consist of the vertical structure of rain reflectivity at 13.4 and 35.6 GHz, and at both co-polarization and crosspolarization, as well as vertical Doppler measurements and crosswind measurements. APR-2 normally flies on the NASA DC-8 aircraft, as in GRIP, collecting data with a downward looking, cross-track scanning geometry. The scan limits are 25 degrees on either side of the aircraft, resulting in a roughly 10-km swath, depending on the aircraft altitude. Details of the APR-2 observation geometry and performance can be found in Sadowy et al. (2003).The multiparameter nature of the APR-2 measurements makes the collection of tropical cyclone measurements valuable for detailed studies of the processes, microphysics and dynamics of tropical cyclones, as well as weaker systems that are associated with tropical cyclone formation. In this paper, we give a brief overview of how the APR-2 data are processed. We also discuss use of the APR-2 cross-track winds to estimate various quantities of interest in in studies of storm intensification. Finally, we show examples of the standard products and derived information.

  16. Salvage treatments for prostatic radiation failure; Traitements de rattrapage apres radiotherapie prostatique

    Energy Technology Data Exchange (ETDEWEB)

    Baumert, H. [Service d' urologie, groupe hospitalier Paris Saint-Joseph, 75 - Paris (France)

    2010-10-15

    Local recurrence after external radiotherapy or brachytherapy occurs in 30% of patients treated for prostate cancer. These recurrences can be localised to the prostate and controlled by salvage treatment. Salvage prostatectomy is the gold standard treatment, however, it is associated with a high morbidity rate. Minimally invasive treatments such as cryo-therapy and high intensity focused ultrasound (HIFU) can be proposed to treat local recurrences. Indications, complications and oncological results of these salvage treatments are discussed in this article. (author)

  17. Respirators: APR Issuer Self Study 33461

    Energy Technology Data Exchange (ETDEWEB)

    Chochoms, Michael [Los Alamos National Laboratory

    2016-07-13

    Respirators: APR Issuer Self-Study (course 33461) is designed to introduce and familiarize employees selected as air-purifying respirator (APR) issuers at Los Alamos National Laboratory (LANL) with the responsibilities, limitations, procedures, and resources for issuing APRs at LANL. The goal is to enable these issuers to consistently provide proper, functioning APRs to authorized users

  18. Traitement des eaux par électrofloculation

    OpenAIRE

    Cansado, Isabel

    1997-01-01

    Traitement des eaux par electrofloculation Les écosystèmes aquatiques sont très affectés par les eaux de rejet qui sont déversées dans les cours d’eau. La charge de ces eaux existe sous diverses formes: solutés, colloïdes ou particules. Il est important de traiter l’eau usée à de faibles coûts au lieu de la rejeter directement dans le milieu récepeteur. Dans le but d’améliorer les procédés physico-chimiques de déstabilisation des émulsions, nous étudions les traitements par électrocoagulat...

  19. Conception et performances des filtres plantés de roseaux pour le traitement des eaux de lavage de salles de traite

    OpenAIRE

    Liénard, A.; Esser, D.; Houdoy, D.; Sabalcagaray, P.

    2003-01-01

    Initialement conçus pour le traitement des eaux usées domestiques, les filtres plantés de roseaux (FPR) ont été modifiés pour étudier l'intérêt et la faisabilité du traitement des effluents issus des fermes bovines laitières, en alternative au stockage avec les déjections liquides (lisier, purin) et à leur épandage sur des terres agricoles, bien que cette dernière solution soit toujours possible après mise aux normes des bâtiments d'élevage dans le cadre du programme de maîtrise des pollution...

  20. Traitement informatique des langues et recherche documentaire

    OpenAIRE

    Victorri, Bernard

    1999-01-01

    Le développement d'Internet et d'autres technologies de l'information représente un nouveau défi pour la recherche en informatique documentaire. Dans cet article, nous montrons que de nouvelles techniques de traitement automatique des langues (comme la segmentation en syntagmes non-récursifs, l'analyse distributionnelle et la résolution d'anaphores) peuvent contribuer à améliorer les performances des systèmes de recherche documentaire.

  1. Diagnostic Strategy in APR1400

    International Nuclear Information System (INIS)

    These features may bring out changes in operator tasks, changing the characteristics of tasks, or creating new tasks. Diagnostic strategy for identifying anomaly may be different especially in APR1400 from that in the analog control room due to the change of human-system interface, i.e. alarm system and display system. Since the first plant of APR1400 is being built at this moment, it is not known what strategies the operators will adopt in diagnosis tasks in the new operating environment. In this light, this paper aims at investigating operator's diagnostic strategies which are appropriate for APR1400. In order to collect data, several different approaches which are complementary are used to identify diagnostic strategies in the digital control room: analysis on audio/video recording of operation, observation in the simulator, and interview with the operators. The result shows that the digital control room introduces new strategies in the diagnosis, compared with the analog control room, and also changed the characteristics of strategies, mostly, by getting more support from the computerized system. This paper investigated how the digitalized control room may influence operator's diagnostic strategies. Several different approaches, i. e., audio/video record, observation of training, and the interview with operators, were used to gather information about the operator's behaviors. As a conclusion, this paper figured out that the digital control room introduces new strategies in the diagnosis, compared with the analog control room, and also changed the characteristics of the strategies, mostly, by getting more support from the computerized system. The operators interviewed also commented that the diagnosis in the APR1400 is quicker, more correct, and easier, compared with the analog control room

  2. L'association ampicilline-sulbactam, une alternative intéressante dans le traitement des infections gonococciques non compliquées

    OpenAIRE

    Miailhes, P.; Hingstman, F.; Louis, F.J.; Cot, Michel

    1992-01-01

    Devant l'importance des résistances des gonocoques aux pénicillines et aux tétracyclines au Cameroun, il est nécessaire de proposer de nouvelles thérapeutiques anti-infectieuses. L'association ampicilline-sulbactam a été testée chez 15 sujets (6 femmes, 9 hommes) dans les gonococcies récentes non compliquées (uréthrite, cervicite). Ce traitement minute par voie intramusculaire était administré après confirmation du diagnostic d'infection gonococcique par un examen bactériologique direct color...

  3. Texture et Anisotropie du comportement mécanique après laminage à chaud d'un alliage léger Aluminium Cuivre Lithium (2050) pour l'aéronautique

    OpenAIRE

    Contrepois, Quentin

    2010-01-01

    Ce travail vise à comprendre l’évolution de la texture cristallographique et l’anisotropie du comportement mécanique après laminage à chaud et traitements thermiques d’un Al-Cu-Li 2050 et d’un Al-Zn-Mg-Cu 7050, et expliquer leurs différences. La texture est analysée par EBSD et RX après des essais de compression plane à chaud et après des laminages à chaud industriels. L’anisotropie est étudiée sur des tôles fortes industrielles après différents détensionnements et dans différents états micro...

  4. Mechanistic studies of APR-246 in leukemia

    OpenAIRE

    Ali, Dina Mahmoud

    2013-01-01

    PRIMA-1and its analog APR-246 are novel drugs that restore the active conformation of mutated and unfolded p53 protein and induce apoptosis and cell death in various tumors in pre-clinical models. We first aimed to explore the effects of APR-246 alone and in combination with other drugs in acute myeloid leukemia (AML) in vitro. APR-246 induced dose-dependent apoptosis and increased active caspase-3 and p53 protein levels as well as the Bax/Bcl-2 ratio independently of TP53...

  5. Heat treatment of uranium-bearing shale; Traitement thermique des schistes uraniferes

    Energy Technology Data Exchange (ETDEWEB)

    Michel, P

    1959-03-01

    In view of the difficulties encountered in rendering soluble the uranium content of shales worked in the Vosges region, and in their filtration after attack, the effects of heat treatment at high temperatures (300 to 600 deg. C) on these two factors is discussed. The first part deals with tests in static beds, the second in fluid beds. In both cases calorie recovery is discussed. The treatment improves filtration but not solubility. (author) [French] Compte tenu des difficultes rencontrees dans la solubilisation de 1'uranium contenu dans les schistes des Vosges, et dans leur filtration apres attaque, ce rapport etudie l'influence du traitement a temperature elevee (300 - 600 deg C) ou grillage sur ces deux facteurs. Dans une premiere partie, sont decrits des essais en lit statique, dans une seconde partie des essais en lit fluide. Dans les deux cas, une recuperation des calories degagees a ete envisagee. il y a amelioration de la filtration mais non de la solubilisation de l'uranium. (auteur)

  6. Incidence et traitement des lymphocèles après greffe rénale

    OpenAIRE

    Molteni T.

    2012-01-01

    1.1. La greffe de rein La greffe d'organes a révolutionné la médecine. De tout le temps elle a suscité les fantasmes et les rêves : la pratique est ancestrale ; elle remonte au 3ème siècle lorsque Saint Côme et Saint Damien réalisent pour la première fois une greffe de jambe de Maure sur un patient. Il faudra néanmoins attendre le 20ème siècle pour voir la transplantation se réaliser plus concrètement avec succès et se généraliser. A Vienne, en 1902, le Dr. Ulmann (1861-1937) pratique la tout...

  7. Curiethérapie dans le traitement palliatif du cancer de l’œsophage

    Science.gov (United States)

    Toulba, Ahmedou; Bakkali, Hanae; Boutayeb, Salwa; Kebdani, Tayeb; Ahid, Samir; Benjaafar, Noureddine

    2015-01-01

    Les patients atteints du cancer de l’œsophage ont souvent une maladie localement avancée, la dysphagie est le symptôme majeur chez la plupart de ces patients, plusieurs modalités thérapeutiques ont été utilisées pour améliorer cette dysphagie. Le but de ce travail est d’étudier l'efficacité et la tolérance de la curiethérapie haut débit de dose (HDR) endo-luminale dans le traitement palliatif des cancers de l’œsophage inopérable. Sur une période de 15 ans, l’étude a inclus les patients atteints de cancer de l’œsophage inopérable et/ou métastatique avec une dysphagie, sans extension à l'hypopharynx ou a la trachée et qui ont bénéficié d'une curiethérapie HDR avec ou sans radiothérapie externe à visée palliative. Au total 46 patients ont été inclus dans l’étude, 58,7% étaient des hommes, 42,2% avaient une dysphagie grade 2 et 37,8% étaient aphagiques, 78,6% des patients étaient performance satus PS 2, l'amaigrissement à été trouvé chez 81,4%, la localisation de la tumeur était surtout au niveau du tiers moyen et inférieur dans 97,8%, la hauteur médiane de la tumeur était de 7 cm (5,5-9), le carcinome épidermoïde était le type histologique le plus fréquent chez 31 patients (70,5%). Après un médiane de suivi de 5 mois, l'amélioration de la dysphagie a été retrouvée chez 76% des malades (p1]. L′incidence la plus élevée est observée dans certains pays notamment en Asie et en Afrique, et l′incidence dans les pays développés occidentaux est en augmentation [2]. Selon le registre du cancer de Rabat 2006-2008, le cancer de l’œsophage est rare et constitue 1,5% de tous les cancers chez l'homme [3]. Le taux de survie globale à 5 ans est de 8%, avec 80% des décès liés à l’évolution locale de la maladie [4]. Pour la minorité des patients avec une maladie localisée, le traitement par radiochimiothérapie concomitante avec ou sans chirurgie permet une amélioration de la survie [5]. Plus de 50

  8. Coping Capability of APR Against Fukushima Accidents

    International Nuclear Information System (INIS)

    Major threats on Fukushima Daiichi plant are earthquake, tsunami, SBO (Station Black Out), and hydrogen burning and explosion. Following the 9.1 magnitude earthquake, tsunami of 15m-height caused Emergency Diesel Generator (EDG) trouble and SBO. APR+ (Advanced Power Reactors Plus) has been basically designed to have the seismic design basis of Safe Shutdown Earthquake (SSE) 0.3g, a 4-train safety concept based on N+2 design philosophy, and a Passive Auxiliary Feedwater System (PAFS). Safety issues on the Fukushima-type accident have been extensively reviewed to enhance APR+ safety. After the review, many items was selected in the APR+ standard design to cope with the accidents. The items can be categorized as follows; Design of structure and equipment against earthquakes and coastal flooding, Integrity of electric power, cooling, and fire protection systems on inundation, Countermeasures against severe accident, and Emergency response and emergency medical systems. The key items include enhancement of seismic design for Main Control Room (MCR) and capability of cooling water intake, improvement of facilities entrance such as a water tight door against tsunami or flood, provision for external cooling water of PCCT (Passive Condensate Cooling Tank), diversity design for emergency electric power sources, and capability extension of a battery for supporting the 72-hour copying time. These items to enhance the safety will have been applied to the APR+ design. Consequently, APR+ can provide higher reliability and safety against tsunami and earthquake

  9. Separate Effect Test for APR+ DVI+

    International Nuclear Information System (INIS)

    DVI and FD are our own design features adopted into APR1400. This study focuses on improving their performance for the APR+. From a preliminary study, conceptual design for DVI+ has been developed. Various separate effect tests were performed to evaluate the performance of the design concept and to develop a basic design. For DVI+ design, tests for DVI duct performance and vibration characteristics were performed. For FD+ design, sensitivity tests for major design parameters were performed. This study also includes a development of design for the reactor flow distribution test as well as FD+ overall performance test

  10. Un jeu de tir LASER ou comment mélanger le traitement de signal, l'électronique et l'assembleur

    Directory of Open Access Journals (Sweden)

    Rocacher T.

    2013-07-01

    Full Text Available Cet article présente une maquette pédagogique qui sert de support aux enseignements de troisième année de la filière MIC (Modélisation Informatique et Communication, option Informatique et Réseaux. Cette maquette ludique permet d'illustrer sous la forme d'un bureau d'étude les domaines du traitement du signal, de l'électronique analogique, de la programmation en langage d'assemblage (ARM Cortex-M3. Elle sert à nouveau en quatrième année lors de la formation sur les périphériques de microcontrôleur (STM32F103. Il s'agit d'un jeu composé de plusieurs pistolets LASER et d'une cible électronique. But du jeu : plusieurs joueurs tirent simultanément sur une cible. La cible doit indiquer le nombre de fois où chaque tireur a fait mouche. Pour ajouter à la difficulté, un son doit être émis à chaque « impact » Après une description du dispositif et du principe de fonctionnement, la structure des pistolets est détaillée ainsi que celle de la cible. Nous présentons ensuite le contenu pédagogique, en commençant par l'aspect traitement du signal, poursuivant avec l'électronique de traitement du capteur, et enfin en détaillant la programmation assembleur.

  11. Les interventions après feu

    OpenAIRE

    Toutchkov, M.; Duché, Y.; Prevosto, B.; Quesney, T.; Vennetier, M.

    2013-01-01

    This chapter presents various post-fire management options for Pinus halepensis stands / Ce chapitre présente les différentes manière de gérer l'après-feu dans les peuplements de pin d'Alep incendiés

  12. Conception et Réalisation d’une Application basée sur l’Architecture SOA : Traitement des Appels d’Offres.

    OpenAIRE

    CHAIF, Lamia

    2014-01-01

    Le travail de PFE qui nous a été confié consistait à contribuer à une étude qui vise à intégrer une architecture technique de type SOA dans un système d‟information. Pour cette étude nous avons retenu un système de traitement des appels d‟offre. Après l‟étude du domaine des appels d‟offre, nous avons retenu les étapes de processus d‟appels d‟offre selon son type. Une fois que nous avons acquises des connaissances sur l‟architecture SOA basée sur les services réutilisables, nous avons...

  13. Superposition tridimensionnelle (3-D) sur la base du crâne pour l’évaluation longitudinale des effets de la croissance et du traitement

    OpenAIRE

    Cevidanes, Lucia H. S.; Styner, Martin; Proffit, William R.; Ngom, Traduit par Papa Ibrahima

    2009-01-01

    RÉSUMÉ – Pour évaluer les modifications liées à la croissance ou au traitement, il est nécessaire de superposer les céphalogrammes successifs sur une structure stable. En céphalométrie bidimensionnelle (2-D), la base du crâne est souvent utilisée pour les superpositions parce que les changements qu’elle subit après le développement cérébral sont mineurs. Toutefois, sur les céphalogrammes de profil et de face, les points de repère basicraniens sont peu fiables. Dans cet article, nous présenton...

  14. Traitement-recyclage du combustible nucléaire usé : La séparation des actinides - Application à la gestion des déchets

    OpenAIRE

    LECOMTE, Michaël; BONIN, Bernard

    2008-01-01

    Après son passage en réacteur, le combustible nucléaire usé contient encore beaucoup de matières valorisables au plan énergétique (uranium, plutonium), ainsi que des produits de fission et actinides mineurs qui représentent les résidus des réactions nucléaires. Le traitement-recyclage du combustible usé, tel qu'il est pratiqué en France, implique la séparation chimique de ces matières. Le développement de ce procédé et sa mise en œuvre industrielle représentent un haut fait de la science et d...

  15. Traitement ou recyclage... Les réacteurs biphasiques au service du traitement de l'air

    OpenAIRE

    Gillet, Sébastien

    2009-01-01

    Ces dernières années, la pollution de l’air est devenue une préoccupation pour ses impacts environnementaux et sur la santé. Les réglementations contrôlant les émissions d’air pollué se sont d’ailleurs multipliées. Face à ces problèmes, des solutions de traitement ont été développées, certaines utilisant même les potentialités des microorganismes pour épurer les effluents industriels. Les limites de ces traitements biologiques classiques sont même en voie d’être repoussées par ...

  16. ÉTUDE DU TRAITEMENT DES SILOXANES PAR ADSORPTION SUR MATÉRIAUX POREUX : APPLICATION AU TRAITEMENT DES BIOGAZ

    OpenAIRE

    Ricaurte Ortega, Deyanira

    2009-01-01

    Étude du traitement des siloxanes par adsorption sur matériaux poreux : application au traitement des biogaz Les biogaz sont des mélanges à forte teneur en méthane utilisés dans la production de chaleur ou d'électricité. Ils contiennent des quantités plus ou moins importantes de siloxanes qui sont interdits pour de nombreuses utilisations du biogaz. La possibilité d'élimination des siloxanes par adsorption est étudiée. Une étude en réacteurs statiques permet d'évaluer les capacités d'adsorpti...

  17. Containment performance analysis for EU APR1400

    International Nuclear Information System (INIS)

    During a severe accident, as the last barrier of DID (Defense In Depth) strategy, the containment has an important role to limit the release of the radioactive material to environment. The containment should be able to maintain its structural integrity to prevent the release of the radioactive materials contained in it. In this paper, the behavior of pressure and temperature in the containment is evaluated for various accident conditions. EU APR1400 (European APR1400) is equipped with RDS (Rapid Depressurization System), HMS (Hydrogen Mitigation System), SACSS (Severe Accident Containment Spray System), and PECS (Passive Ex vessel Cooling System) to mitigate the severe accident consequences and eventually to keep the containment integrity. Depending on the availabilities of these mitigation systems, the containment undergoes different transients in pressure and temperature

  18. Les Determinants du Desir De Grossesse chez les Femmes Seropositives sous Traitement AntiRetroviral dans le District de Rwamagana

    Directory of Open Access Journals (Sweden)

    Claudien Uwanyirigira

    2013-06-01

    Full Text Available L’étude vise à analyser les déterminants du désir de grossesse chez les femmes séropositives sous traitement anti-retroviral, afin de contribuer à la réduction de la transmission du virus de la mère à l’enfant. Elle a pour objectifs spécifiques de déterminer la proportion des grossesses chez les femmes à sérologie VIH positive, d’évaluer l’attitude du personnel de santé à l’égard des messages à donner aux femmes séropositives sous ARVs en ce qui concerne le désir de la grossesse, et relever les facteurs déterminant le désir d’avoir des enfants après la mise ne route d’un traitement par antirétroviraux . Il s’agit d’une étude descriptive transversale. Elle a été conduite auprès de 260 femmes infectées par le VIH sous ARVs et suivies dans les FOSA, ayant les services de VCT/PMTCT et des ARVs. L’étude montre que 26,9% des femmes ont été enceintes après avoir été informées de leur statut sérologique positif pour le VIH et que 38,5% des femmes séropositives sous traitement anti-rétroviral désirent avoir des enfants dans le futur. La majorité des femmes (82,7% reconnaissent l’importance de l’utilisation des contraceptifs alors que le pourcentage des femmes qui connaissent l’importance d’utiliser les ARVs pendant la grossesse et l’accouchement pour réduire le risque de transmission de la mère à l’enfant est de 76,9%. Les facteurs déterminant le désir de la grossesse parmi les femmes séropositives sont : La confiance attribuée aux anti-rétroviraux, la parité c’est-à-dire les femmes qui n’ont pas eu d’enfant ont un désir de maternité deux fois supérieur que les femmes qui ont eu au moins un enfant, et la non utilisation des méthodes contraceptives chez les femmes à sérologie VIH positives pour réduire le risque de transmission de la mère à l’enfant. Nous recommandons de renforcer l’intégration des activités de santé de la reproduction et de Planning

  19. Optimisation des proprietes fonctionnelles des alliages a memoire de forme suite a l'application de traitements thermomecaniques

    Science.gov (United States)

    Demers, Vincent

    L'objectif de ce projet est de determiner les conditions de laminage et la temperature de traitement thermique maximisant les proprietes fonctionnelles de l'alliage a memoire de forme Ti-Ni. Les specimens sont caracterises par des mesures de calorimetrie, de microscopie optique, de gene ration de contrainte, de deformation recuperable et des essais mecaniques. Pour un cycle unique, l'utilisation d'un taux d'ecrouissage e=1.5 obtenu avec l'application d'une force de tension FT = 0.1sigma y et d'une huile minerale resulte en un echantillon droit, sans microfissure et qui apres un recuit a 400°C, produit un materiau nanostructure manifestant des proprietes fonctionnelles deux fois plus grandes que le meme materiau ayant une structure polygonisee. Pour des cycles repetes, les memes conditions de laminage sont valables mais le niveau de deformation optimal est situe entre e=0.75-2, et depend particulierement du mode de sollicitation, du niveau de stabilisation et du nombre de cycles a la rupture requis par l'application.

  20. Récupération après reconstruction du ligament croisé antérieur et prévention des ruptures : étude biomécanique d'un mouvement pluri-articulaire

    OpenAIRE

    Pairot de Fontenay, Benoît

    2014-01-01

    La reconstruction chirurgicale est le traitement préconisé après rupture du Ligament Croisé Antérieur (LCA) chez les patients sportifs. Cette opération est suivie d'une longue période de rééducation et les résultats en termes de reprise du sport et de récidive ne sont pas totalement satisfaisants. Ainsi ce travail s'articule autour de deux objectifs : l'amélioration de la récupération après lésion du LCA et la prévention des primo-ruptures. Dans un premier temps, nous avons évalué les altérat...

  1. Apreçamento de derivativos bidimensionais

    Directory of Open Access Journals (Sweden)

    Hugo Daniel de Oliveira Azevedo

    2005-09-01

    Full Text Available Neste artigo analisamos o apreçamento de contratos que tenham seus resultados atrelados a mais de um ativo subjacente, em especial, opções bidimensionais. Para isto usamos a fórmula desenvolvida por Margrabe (1978 e o modelo de árvores de Rubinstein (1991a. Em seguida apresentamos exemplos práticos de opções bidimensionais e apreçamos estas opções. Além disto, sugerimos a incorporação de outros instrumentos, negociados no exterior, ao mercado de derivativos brasileiro.In this article we analyze the pricing of contracts that have their payoffs linked to more than one underlying asset, in special, bidimensional options. To achieve this purpose we use the formula developed by Margrabe (1978 and the tree model of Rubinstein (1991a. Next, we present practical examples of bidimensional options and price these options. Moreover we suggest the incorporation of two other instruments, negotiated abroad, to the Brazilian derivative markets

  2. Design Characteristics of the Passive Auxiliary Feedwater System in APR+

    International Nuclear Information System (INIS)

    The passive auxiliary feedwater system (PAFS) is a typical passive safety system implemented for the APR+. The auxiliary feedwater system (AFWS) in the APR1400, which is the reference plant of the APR+, consists of two motor driven pumps, two turbine driven pumps, two water storage tanks, and related pipes and valves. The AFWS feeds emergency water to steam generators to cool down the reactor coolant system when the main feedwater is lost. To enhance the safety, the PAFS replaces the AFWS with a passive condensation heat exchanger (PCHX), a passive condensation cooling tank (PCCT), and a few valves and pipes in the APR+ design. In this paper, we propose the design requirements and conceptual design of the PAFS in order to evaluate the operability of the PAFS, to develop the APR+'s general arrangements for the auxiliary building, and to identify the important parameters to be quantified by experiments

  3. Design Characteristics of the APR+ Containment Spray System

    International Nuclear Information System (INIS)

    We, KEPCO E and C, are implementing APR+ design development phase II project, which is owned by the KHNP. The APR+ Containment Spray (CS) System is developed as a four (4) 100%-capacity train system which shares the pumps, heat exchangers, valves, and piping with the Shutdown Cooling (SC) System, meeting the N+2 design concept (capable of satisfying the safety function with a single failure and a concurrent component unavailability due to maintenance) and still maintaining the number and capacity of the system components similar to the APR1400 CS System and SC System combined. The design concept and system configuration of the APR+ CS System are presented

  4. Design Characteristics of the APR+ Containment Spray System

    Energy Technology Data Exchange (ETDEWEB)

    Doh, Gyu Bong; Park, Jong Ha; Chang, Jae Wang [KEPCO Engineering and Construction Co., Yongin (Korea, Republic of)

    2012-05-15

    We, KEPCO E and C, are implementing APR+ design development phase II project, which is owned by the KHNP. The APR+ Containment Spray (CS) System is developed as a four (4) 100%-capacity train system which shares the pumps, heat exchangers, valves, and piping with the Shutdown Cooling (SC) System, meeting the N+2 design concept (capable of satisfying the safety function with a single failure and a concurrent component unavailability due to maintenance) and still maintaining the number and capacity of the system components similar to the APR1400 CS System and SC System combined. The design concept and system configuration of the APR+ CS System are presented

  5. Performance analysis of a Passive Auxiliary Feedwater System in APR+

    International Nuclear Information System (INIS)

    The Advanced Power Reactor Plus (APR+), which is a GEN III+ reactor based on the APR1400, is being developed in Korea. In order to enhance the safety of the APR+, a passive auxiliary feedwater system (PAFS) has been adopted in the APR+. The PAFS replaces the conventional active auxiliary feedwater system (AFWS) by introducing a natural driving force mechanism while maintaining the system function of cooling the primary side and removing the decay heat. The purpose of this paper is to evaluate the performance of the PAFS under design basis events using best-estimated thermalhydraulic codes

  6. Vingt ans après…

    Directory of Open Access Journals (Sweden)

    François Burgat

    2002-05-01

    Full Text Available Le dixième numéro des Chroniques Yéménites, publié vingt ans après la création du Centre Français d'Archéologie et de Sciences Sociales de Sanaa reflète des ambitions souvent exprimées: donner une chance aux jeunes chercheurs et couvrir un large éventail disciplinaire au service de l'affirmation de la vocation régionale du Centre. Depuis Sanaa ou Paris, chercheurs, doctorants ou stagiaires, de l'Ecole normale supérieure, de l'INALCO, de l'Université de Sanaa et de bon nombre d'institu...

  7. Technologie de Traitement de la Fondation pour l’Exécution des Ponts de l’Autoroute

    Institute of Scientific and Technical Information of China (English)

    Liu Haoyu

    2015-01-01

    Sommaire: Le présent texte se concentre principalement sur la recherche des problèmes relatifs à la fondation des ponts de l’autoroute, qui a pour objet d’améliorer la technologie de traitement de la fondation des ponts de l’autoroute, tout en proposant des mesures de traitement auxquelles on peut se référer lors du traitement de la fondation des ponts de l’autoroute.

  8. Étude d'un bioréacteur anaérobie à membranes immergées pour le traitement des eaux résiduaires

    OpenAIRE

    Rodriguez Susa, Manuel

    2005-01-01

    Un bioréacteur anaérobie à membranes a été étudié comme alternative technologique pour le traitement des eaux résiduaires. L'originalité de ce travail réside dans l'utilisation simultanée d'une biomasse de type granulaire et d'un système de membranes immergées. Le procédé a été étudié en continu pendant 300 jours sous conditions psychrophiles (20°c). Une caractérisation des conditions hydrauliques et de la répartition des particules dans le bioréacteur a été réalisée. Après 300 jours de trava...

  9. Performance Analysis of APR+ PAFS for CDF evaluation

    International Nuclear Information System (INIS)

    The Advanced Power Reactor Plus (APR+), which is a GEN III+ reactor based on the APR1400, is being developed in Korea. In order to enhance the safety of the APR+, a passive auxiliary feedwater system (PAFS) has been adopted. The PAFS replaces the conventional active auxiliary feedwater system (AFWS) by introducing a natural driving force mechanism while maintaining the system functions of cooling the primary side and removing the decay heat. As the PAFS completely replaces the conventional active auxiliary feedwater system (AFWS), it is necessary to verify its cooling capacity for the core damage frequency (CDF) evaluation. This paper discusses the cooling performance of the PAFS in transient accidents

  10. Performance Analysis of APR+ PAFS for CDF evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Sang Hee; Kim, Han Gon [Korea Hydro and Nuclear Power Co., Daejeon (Korea, Republic of)

    2011-05-15

    The Advanced Power Reactor Plus (APR+), which is a GEN III+ reactor based on the APR1400, is being developed in Korea. In order to enhance the safety of the APR+, a passive auxiliary feedwater system (PAFS) has been adopted. The PAFS replaces the conventional active auxiliary feedwater system (AFWS) by introducing a natural driving force mechanism while maintaining the system functions of cooling the primary side and removing the decay heat. As the PAFS completely replaces the conventional active auxiliary feedwater system (AFWS), it is necessary to verify its cooling capacity for the core damage frequency (CDF) evaluation. This paper discusses the cooling performance of the PAFS in transient accidents

  11. Contribution à l’amélioration de la lutte contre le paludisme en République Démocratique du Congo (RDC) :Efficacité du traitement préventif intermittent (TPI) de la femme enceinte à la sulfadoxine-pyriméthamine (SP) en contexte d’émergence de la résistance du Plasmodium falciparum, Adhérence des prestataires de soins et des patients à l’association artesunate-amodiaquine (AS-AQ) après changement de la politique nationale de traitement du paludisme simple, Paludisme sévère chez l’enfant à Kisangani (aspects cliniques et évolutifs). / Contribution to the improvement of malaria control in Democratic Republic of Congo (DRC): Effectiveness of intermittent preventive treatment (IPT) for pregnant women with sulfadoxine-pyrimethamine (SP) in the context of emergence of resistance of Plasmodium falciparum, Adherence of healthcare providers and patients to artesunate-amodiaquine (AS-AQ) after the changement of national policy for treatment of uncomplicated malaria, Severe malaria in children in Kisangani (clinical and evolutive aspects).

    OpenAIRE

    Losimba Likwela, Joris

    2012-01-01

    Deuxième pays le plus endémique pour le paludisme au monde, la république démocratique du Congo (RDC) a adopté officiellement l’initiative Faire Reculer le Paludisme en 2001 et depuis, aligne sa politique de lutte contre le paludisme sur les directives de l’OMS dont les orientations les plus récentes consistent en 3 stratégies :[1] assurer aux malades un accès rapide à un traitement efficace et abordable, [2] assurer aux personnes exposées au risque, notamment les jeunes enfants et les femmes...

  12. Peut-on réaliser une analgésie péridurale après un blood patch récent?

    Science.gov (United States)

    Chkoura, Khalid; Kechna, Hicham; Loutid, Jaouad; Ouzad, Omar; Hachimi, Moulay Ahmed; Hannafi, Sidi Mohamed

    2015-01-01

    Le blood patch constitue le traitement de référence du syndrome post ponction lombaire. Son efficacité a été démontrée par plusieurs essais randomisés comparant le BPE aux mesures conservatrices et au placebo. Il consiste en l'injection d'une quantité de sang autologue dans l'espace péridurale afin d'obturer la brèche dure-mérienne. La réalisation d'une analgésie péridurale après antécédent de blood patch est possible, malgré la persistance de questions sur les délais de retour à la normal de l'espace péridurale. Nous rapportons un cas où une analgésie péridurale a été réalisée avec succès trois semaines après un blood patch. PMID:26600909

  13. Involvement of Stringent Factor RelA in Expression of the Alkaline Protease Gene aprE in Bacillus subtilis

    OpenAIRE

    Hata, Michihiro; Ogura, Mitsuo; Tanaka, Teruo

    2001-01-01

    Expression of Bacillus subtilis aprE, encoding an extracellular alkaline protease, is positively regulated by phosphorylated DegU, the regulator of a two-component regulatory system, DegS-DegU. We found that the expression of an aprE′-′lacZ fusion was greatly reduced in a disruption mutant with a mutation of relA, which encodes the stringent factor RelA. The level of DegU in the relA mutant was similar to that in the wild-type cell. A relA degU double mutation did not result in a further decr...

  14. The development of a passive auxiliary feedwater system in APR+

    International Nuclear Information System (INIS)

    The Advanced Power Reactor Plus (APR+) is being developed in Korea. APR+ is a GEN III+ reactor on the basis of the APR1400. To meet the requirements of GEN III+ reactors, the economics and the safety of the APR+ are further enhanced. One of the basic principles of APR+ safety systems is the adoption of hybrid safety systems. Passive safety systems replace the current active safety systems from an economic point of view. The passive aux. feedwater system (PAFS) is one of the passive safety features adopted in the APR+. The PAFS replaces the conventional active auxiliary feedwater system by introducing a natural driving force mechanism while maintaining the system's basic Junction of cooling down the primary side and removing the decay heat. In order to satisfy the single failure criterion, the PAFS is composed of two independent trains. Each train has one steam condensing heat exchanger of 100% capability and one PCCT (Passive Condensation Cooling water Tank) of 100% capability. Basic design is underway and separate effect tests and integral effect tests will be performed to demonstrate the performance of the PAFS. (authors)

  15. Use of iodine-125 brachytherapy in treatment of choroidal melanomas, technic and preliminary analysis of 78 patients; Traitement conservateur des melanomes choroidiens par curietherapie par l'iode 125, technique et analyse preliminaire d'une serie de 78 patients

    Energy Technology Data Exchange (ETDEWEB)

    Quetin, P.; Schumacher, C.; Schraub, S. [Centre Paul-Strauss, Dept. de Radiotherapie, 67 - Strasbourg (France); Meyer, L.; Polto, F.; Sahel, J. [Hopitaux Universitaires de Strasbourg, Clinique Ophtalmologique, 67 (France); Magnenet, P. [Centre Paul-Strauss, Dept. de Radiophysique, 67 - Strasbourg (France); Andres, E. [Hopital de Hautepierre, Medecine Interne, 67 - Strasbourg (France)

    2001-12-01

    Purpose. - Iodine 125 curietherapy is one of the conservative treatments of uveal melanoma. The technique used to achieve these results was simplified through the physical characteristics of the radioelement and the optimized-dosimetry program employed. Patients and methods. - 78 patients with choroidal melanoma were treated with iodine 125. About 100 Gy were delivered to the superior pole of the tumour. The minimal length of follow-up was 17 months and the average, 67 months. Results. -There was 88% local control, leading to lowered visual acuity in 76 % of the cases. Radiation retinopathy, directly related to proximity to the macula, is the principle etiology. Seven patients died of hepatic metastasis, five patients were enucleated. Four patients were further treated with proton-therapy to make up for non-control locally. Conclusion. -One dose of 100 Gy to the superior pole of the tumor seemed to lead to good local control, with the exception of complications related to proximity to the macula and the optic nerve. In this attempt to optimize irradiation, the time lapse between any benefit in local control derived from irradiation and post-therapeutic complications observed remains insufficient to evaluate any relationship. (authors)

  16. Traitement FrameNet des constructions à attribut de l'objet

    OpenAIRE

    Djemaa, Marianne

    2014-01-01

    Dans le cadre du projet ASFALDA, qui comporte une phase d'annotation sémantique d'un FrameNet fran-çais, nous cherchons à fournir un traitement linguistiquement motivé des constructions à attribut de l'objet, un exemple typique de divergence syntaxe-sémantique. Pour ce faire, nous commençons par dresser un panorama des propriétés syntaxiques et sémantiques des constructions à attribut de l'objet. Nous étudions ensuite le traitement FrameNet des verbes anglais typiques de cette construction, a...

  17. Environnements et langages de programmation visuels pour le traitement de documents structurés

    OpenAIRE

    Pietriga, Emmanuel

    2002-01-01

    L'adoption du langage XML dans de nombreux domaines pour la représentation des documents et des données a simplifié les manipulations associées aux documents du World Wide Web en offrant des solutions d'analyse et de traitement génériques. Ces manipulations se traduisent souvent par des opérations de transformation de la structure et du contenu des documents et jouent un rôle essentiel dans la chaîne de traitement documentaire. Les solutions existantes pour la transformation de documents XML ...

  18. Surimi de chinchard ( Trachurus trachurus L. ) - Influence de conditions technologiques sur des caractéristiques de texture du produit après traitement thermique

    OpenAIRE

    Verrez-Bagnis, Veronique

    1987-01-01

    Surimi, washed fish mince after grinding with salt, has a firm and elastic gel texture or “ashi” after thermal processing. The major objectives of this study on horse mackerel (Trachurus trachurus) surimi are to optimize the technological conditions in the aim to obtain the best ashi, to determine the influence of frozen storage and of egg white and potata starch addition, and to establish the preventive effect of incorporation into surimi of different combinations of cryoprotectants and N...

  19. Management of inflammatory breast cancer after neo-adjuvant chemotherapy; Traitement locoregional du cancer du sein inflammatoire apres chimiotherapie neo-adjuvante

    Energy Technology Data Exchange (ETDEWEB)

    Abrous-Anane, S.; Daveau, C.; Dendale, R.; Campana, F.; Kirova, Y.; Fourquet, A.; Bollet, M.A. [Service d' onco-radiotherapie, institut Curie, 26, rue d' Ulm, 75005 Paris cedex 05 (France); Savignoni, A.; Gautier, C. [Service de biostatistique, institut Curie, 26, rue d' Ulm, 75248 Paris cedex 05 (France); Pierga, J.Y. [Service d' oncologie medicale, institut Curie, 26, rue d' Ulm, 75248 Paris cedex 05 (France); Reyal, F. [Service de chirurgie, institut Curie, 26, rue d' Ulm, 75248 Paris cedex 05 (France)

    2011-12-15

    Purpose. - To assess the benefit of breast surgery for inflammatory breast cancer. Patients and methods. - This retrospective series was based on 232 patients treated for inflammatory breast cancer. All patients received primary chemotherapy followed by either exclusive radiotherapy (118 patients, 51%) or surgery with or without radiotherapy (114 patients, 49%). The median follow-up was 11 years. Results. - The two groups were comparable apart from fewer tumors smaller than 70 mm (43% vs 33%, P = 0.003), a higher rate of clinical stage N2 (15% vs 5%, P = 0.04) and fewer histopathological grade 3 tumors (46% vs 61%, P < 0.05) in the no-surgery group. The addition of surgery was associated with a significant improvement in locoregional disease control (P = 0.04) but with no significant difference in overall survival rates or disease-free intervals. Late toxicities were not significantly different between the two treatment groups except for a higher rate of fibrosis in the no-surgery group (P < 0.0001), and more lymphedema in the surgery group (P = 0.002). Conclusion. - Our data suggest an improvement in locoregional control in patients treated by surgery, in conjunction with chemotherapy and radiotherapy, for inflammatory breast cancer. (authors)

  20. What about sexual life after therapy for prostate cancer?; Y a t-il une vie sexuelle apres traitement d'un cancer prostatique?

    Energy Technology Data Exchange (ETDEWEB)

    Cosset, J.M. [Institut Curie, 75 - Paris (France)

    2002-05-01

    The precise assessment of sexual dysfunction after treatment of prostatic cancer cannot be avoided in 2002. These iatrogenic complications may significantly alter the quality of life of the patients. In addition, sexual toxicity is progressively becoming a cardinal parameter for the treatment choice, both for the patient and the physician. Significant efforts allowed to reduce sexual toxicity after therapy in the recent years. As an example, nerve-sparing surgical techniques have been proposed, whenever reasonable. However, in spite of these surgical advances, data suggest that overall, the new irradiation techniques (conformal radiotherapy and brachytherapy) are responsible for less alteration of sexual life than surgery. Another potential advantage is that sildenafil (Viagra) is able to restore potency in a majority of cases after radiotherapy, while it is usually poorly effective after surgery. (author)

  1. The core design of the advanced power reactor plus (APR+)

    International Nuclear Information System (INIS)

    Advance Power Reactor Plus (APR+), a pressurized water reactor and an improved nuclear power reactor based on the Advanced Power Reactor 1400 MWe (APR1400) in Korea, has been developed with 18-month cycle operation strategy from its initial core. The APR+ core power is 4290 MWth which corresponds to a 1500 MWe class nuclear power plant. The reactor core consists of 257 fuel assemblies. Comparing with APR1400 core design, 16 fuel assemblies are added. Its cycle length is expected about 450 EFPD directly from initial core, although most of previous other plants had been started according to their annual or 15-month cycle operation schedule at their initial core and gone to 18-month after third - fourth cycle. In order to reduce the peaking power, fuel pin configurations of the assembly, are optimized by using some low enriched fuel pins and gadolinia bearings. APR+ core has been met the requirements as well as the above cycle length requirement; 1) peaking factor, 2) Negative MTC(Moderator Temperature Coefficient), 3) sufficient shutdown margin, 4) convergent Xenon stability Index. The maximum rod burnup and the discharge fuel assembly burnup are also satisfied those of the limit. It is expected to acquire the standard design approval by the end of 2012 by the Korean nuclear regulatory. (authors)

  2. Development of Reference Source Terms for EU-APR1400

    International Nuclear Information System (INIS)

    These source terms are developed for the typical U. S. NPP and do not reflect the design characteristics of EU-APR1400 (1,400 MWe PWR) which will be applied for the EUR certification in European countries. The process of developing the RST for EU-APR1400 is to undergo a similar process that NUREG-1465 had gone through when it came out with its proposed source terms. The purpose of this study is to develop the EU-APR1400 design-specific RST complied with the EUR. The Large LOCA is the reference equence used in the NUREG-1465 evaluation, whereas the EUAPR1400 risk-significant sequences are dominated by small LOCA and non-LOCA sequences. Moreover, when considering the EU-APR1400 has many design features to mitigate the consequences of severe accident phenomena, it is not surprising that the aspects of both release fractions and durations are distinctly different from NUREG-1465. This RST will be continuously updated to reflect to the design features of EU-APR1400, and then, be used as the reference for design purposes such as criteria satisfaction of radioactivity releases, equipment survivability, control room habitability for severe accident, and so on

  3. Evaluation du matériel pour les obturations des restaurations préventives, avant et après un stress mécanique et thermal, étude in vitro

    OpenAIRE

    Chaskelis, Ivonne

    2014-01-01

    Le but de cette étude in vitro a été d’évaluer l’adaptation marginale de trois résines différentes utilisées pour le traitement des cavités minimales. 30 molaires humaines supérieures, désignées de façon randomisée, divisées en 3 groupes expérimentaux ont été soumises à des charges mécaniques et thermiques après avoir été obturées par 3 matériaux différents (groupe 1 : Optibond® FL + Optibond® FL, groupe 2 : Optibond® FL + premise® Flow, groupe 3 : Optibond® FL + Premise®). L’adaptation margi...

  4. System Response Analysis of LOCV for APR1400 Using KNAP

    International Nuclear Information System (INIS)

    Korea Electric Power Research Institute (KEPRI) of Korea Electric Power Corporation (KEPCO) has been developed the non-loss-of-coolant accident (non-LOCA) analysis methodology, called as the Korea Non-LOCA Analysis Package (KNAP), for the typical Optimized Power Reactor 1000 (OPR1000) plants. Considering current licensing methodology conducted by ABB-CE, however, the KNAP could be applied to Advanced Power Reactor 1400 (APR1400). In spite of some difference in components of two plant types, there is a close resemblance between their nuclear steam supply systems (NSSS). So, in this study, the loss of condenser vacuum (LOCV) event were analyzed using KNAP for APR1400 to estimate the feasibility of the application and the results were compared with those given in APR1400 Standard Safety Analysis Report (SSAR), which were calculated using the CESEC-III code of ABB-CE. Through the study, it was concluded that the KNAP could be applicable to APR1400 on the view point of LOCV event

  5. Traitement chirurgical des fractures articulaires du calcanéum par plaque vissée

    OpenAIRE

    Hammou, Nassreddine; Abid, Hatim; Shimi, Mohammed; El Ibrahimi, Abdelhalim; El Mrini, Abdelmajid

    2015-01-01

    Les fractures du calcanéum sont peu fréquentes mais le plus souvent graves. Le traitement chirurgical par plaque vissée est ardemment défendu. L'objectif de notre travail rétrospectif est d’évaluer les résultats du traitement chirurgical des fractures articulaires du calcanéum à travers une série de 12 patients opérée aux service d'orthopédie du CHU Hassan II de Fès sur une durée de 3 ans, et les comparer aux données de la littérature. L’âge moyen dans notre série était de 34 ans, le geste op...

  6. SYNDEX un environnement de programmation pour multi-processeur de traitement du signal. Mecanismes de communication

    OpenAIRE

    Ghezal, Nadia; Matiatos, Spiros; Piovesan, Pascal; Sorel, Yves; Sorine, Michel

    1990-01-01

    Syndex (Acronyme pour EXecutif Distribue SYNchrone) est un environnement graphique interactif de developpement d'applications de traitement du signal pour machines multi-processeur. Nous presentons en introduction, les fonctions assurees par Syndex adaptees a la mise en oeuvre sur machines multiprocesseurs de programmes synchrones ecrits dans le langage Signal, quelques methodes d'optimisation associees, la generation et le reglage du support d'execution. Enfin, nous decrivons rapidement le p...

  7. Verbal Communication in the APR1400 Advanced Control Room

    International Nuclear Information System (INIS)

    This paper introduces the characteristics of communication in advanced main controlghd rooms (MCRs) and some observations from a case study performed for APR1400 MCR. In advanced MCRs, operators need not maintain the same communication patterns as they do in conventional ones. For example, a senior reactor operator (SRO) does not have to rely on board operators for information acquisition and can get any information from his/her own workstation. This situation may also bring about new problems in MCRs such as lack of shared situation awareness and collaboration between MCR operators. To cope with these problems, the APR1400 MCR adapts several approaches in design and training for encouraging operators to communicate with each other. This paper introduces the possible changes of communication patterns and the countermeasures in design and training. Some findings from an integrated system validation for Shin Kori Units 3 and 4 are also presented

  8. Nuclear power protection systems performance study for APR 1400

    International Nuclear Information System (INIS)

    A study on plant protection system (PPS) of advanced power reactor (APR) 1400 which is one of the system to maintain nuclear power plant (NPP) operation safe and controllable has been conducted. The controllability aspect of NPP operation is an important aspect to assure the NPP operation safe and reliable. Accordingly, the study is limited in the performance of PPS. The method used in the study includes literature study, data collection, as well as review and analysis. The purpose of this study is to recognize that PPS performance can assure the NPP operation safely and controllable. The study concludes that there are several measurement parameters that actuate PPS systems to trip the reactor such as high pressurizer pressure, low pressurizer pressure, high containment building pressure and also manual trip. These parameters are measured by parallel sensor with parallel arrangement set on set point suitable with APR 1400 safety standard. (author)

  9. Preliminary Results Of LOCA Problem For APR1400 Reactor

    International Nuclear Information System (INIS)

    Several features of NPP with APR1400 nuclear reactor during a loss of coolant accident (LOCA) are investigated in this study. The report describes some main design characteristics of an engineering safety systems of APR1400 and the thermal hydraulic calculation results for steady-state using MARS and RELAP/SCDAPSIM codes. Large Break LOCA accident has been analyzed and evaluated based on acceptable criteria for ECCS given by US NRC. The results from cold leg break LOCA with broken area of 0.0465 m2 in case of high pressure safety injection system (HPSI) failed to operate or 2 and 4 HPSI pumps are activated. The preliminary results of this work is a part of collaboration between INST researchers and KAERI experts in using RELAP tool for safety analysis of NPPs. (author)

  10. Conceptual Design of Passive Containment Cooling System Based on APR+

    Energy Technology Data Exchange (ETDEWEB)

    Jeon, Byongguk; No, Heecheon [Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of)

    2013-05-15

    Passive Auxiliary Feedwater System (PAFS) is expected to work well under extended SBO, but is vulnerable to extended SBO coupled with loss of coolant accident (LOCA). Various reactors have been developed, such as AP1000, ESBWR, and KERENA, with passive containment cooling systems (PCCSs) dealing with the accident scenario of SBO with LOCA. The performance of the PCCSs is already or almost validated. Though PCCS is well adopted into BWRs, there has been no success in PWRs with concrete containment. In this paper, we suggest a new PCCS based on APR+ and represent scoping analysis results. The Fukushima accident proved the importance of treating extended SBO. To deal with extended SBO with LOCA scenario, the PCCS based on APR+ is suggested and evaluated roughly for the first time as a PWR with concrete containment.

  11. Design features of Advanced Power Reactor (APR) 1400 steam generator

    International Nuclear Information System (INIS)

    Advanced Power Reactor 1400 (APR 1400) which is to achieve the improvement of the safety and economical efficiency has been developed by Korea Hydro and Nuclear Power Co., Ltd. (KHNP) with the support from industries and research institutes. The steam generator for APR 1400 is an evolutionary type from System 80+, which is the recirculating U-tube heat exchanger with integral economizer. Compared to the System 80+ steam generator, it is focused on the improved design features, operating and design conditions of APR 1400 steam generator. Especially, from the operation experience of Korean Standard Nuclear Power Plant (KSNP) steam generator, the lessons-learned measures are incorporated to prevent the tube wear caused by flow-induced vibration (FIV). The concepts for the preventive design features against FIV are categorized to two fields; flow distribution and dynamic response characteristics. From the standpoint of flow distribution characteristics, the egg-crate flow distribution plate (EFDP) is installed to prevent the local excessive flow loaded on the most susceptible tube to wear. The parametric study is performed to select the optimum design with the efficient mitigation of local excessive flow. ATHOS3 Mod-01 is used and partly modified to analyze the flow field of the APR 1400 steam generator. In addition, the upper tube bundle support is designed to eliminate the presence of tube with a low natural frequency. Based on the improved upper tube bundle support, the modal analysis is performed and compared with that of System 80+. Using the results of flow distribution and modal analysis, the two mechanisms of flow-induced vibration are investigated; fluid-elastic instability (FEI) and random turbulence excitation (RTE). (authors)

  12. Regulatory Approach for Oversight of APR1400 Constructions

    International Nuclear Information System (INIS)

    This presentation treats of the regulatory approach for the oversight of the APR 1400. It first introduces the licensing system in Korea and after that it describes the inspection program during the construction and commissioning, operation and finally decommissioning phase. Special emphasis is put on the installation inspection (52 items), cold functional inspections (77 items), hydrostatic and hot functional test inspection (23 items) and initial fuel loading and startup test inspections (33 items)

  13. Performance verification test for APR1400 fluidic device

    International Nuclear Information System (INIS)

    Using the full scale test facility called 'VAPER', five sets of repeatability tests have been carried out to verify the performance of the Fluidic Device which is adopted in the standard design of APR1400. Quality assurance program for the APR1400 Fluidic Device verification test has been developed and applied to each set of repeatability test procedure, and precise calibration for major measuring instruments has been performed. Thus, the highest reliability and integrity of the test results was ensured. Throughout the present tests, the repeatability of the major parameter related with APR1400 Fluidic Device performance has been sufficiently confirmed. Total K factor in the actual plant system would be about 16 at high flow condition and about 105 at low flow condition, which is similar to the design goal (about 17 at high flow condition and about 100 at low flow condition) The results of the present research contributes to the smooth construction of Sin-Kori units 3 and 4, and to the promotion of domestic analytic capability for the LOCA of advanced LWR

  14. Pseudomonas syringae evades host Immunity by degrading flagellin monomers with alkaline protease AprA

    OpenAIRE

    Pel, M.J.C.; Van Dijken, A.J.H.; Bardoel, B.W.; Seidl, M. F.; Van der Ent, S.; van Strijp, J. A. G.

    2014-01-01

    Bacterial flagellin molecules are strong inducers of innate immune responses in both mammals and plants. The opportunistic pathogen Pseudomonas aeruginosa secretes an alkaline protease called AprA that degrades flagellin monomers. Here, we show that AprA is widespread among a wide variety of bacterial species. In addition, we investigated the role of AprA in virulence of the bacterial plant athogen P. syringae pv. tomato DC3000. The AprA-deficient DC3000 ΔaprA knockout mutant was significantl...

  15. Engineering and Directed Evolution of a Ca2+ Binding Site A-Deficient AprE Mutant Reveal an Essential Contribution of the Loop Leu75–Leu82 to Enzyme Activity

    OpenAIRE

    Eliel R. Romero-García; Alfredo Téllez-Valencia; María F. Trujillo; José G. Sampedro; Hugo Nájera; Arturo Rojo-Domínguez; Jesús García-Soto; Mario Pedraza-Reyes

    2009-01-01

    An aprE mutant from B. subtilis 168 lacking the connecting loop Leu75–Leu82 which is predicted to encode a Ca2+ binding site was constructed. Expression of the mutant gene (aprEΔLeu75–Leu82) produced B. subtilis colonies lacking protease activity. Intrinsic fluorescence analysis revealed spectral differences between wild-type AprE and AprEΔL75–L82. An AprEΔL75–L82 variant with reestablished enzyme activity was selected by directed evolution. The no...

  16. Design of a load following controller for APR+ nuclear plants

    International Nuclear Information System (INIS)

    A load-following operation in APR+ nuclear plants is necessary to reduce the need to adjust the boric acid concentration and to efficiently control the control rods for flexible operation. In particular, a disproportion in the axial flux distribution, which is normally caused by a load-following operation in a reactor core, causes xenon oscillation because the absorption cross-section of xenon is extremely large and its effects in a reactor are delayed by the iodine precursor. A model predictive control (MPC) method was used to design an automatic load-following controller for the integrated thermal power level and axial shape index (ASI) control for APR+ nuclear plants. Some tracking controllers employ the current tracking command only. On the other hand, the MPC can achieve better tracking performance because it considers future commands in addition to the current tracking command. The basic concept of the MPC is to solve an optimization problem for generating finite future control inputs at the current time and to implement as the current control input only the first control input among the solutions of the finite time steps. At the next time step, the procedure to solve the optimization problem is then repeated. The support vector regression (SVR) model that is used widely for function approximation problems is used to predict the future outputs based on previous inputs and outputs. In addition, a genetic algorithm is employed to minimize the objective function of a MPC control algorithm with multiple constraints. The power level and ASI are controlled by regulating the control banks and part-strength control banks together with an automatic adjustment of the boric acid concentration. The 3-dimensional MASTER code, which models APR+ nuclear plants, is interfaced to the proposed controller to confirm the performance of the controlling reactor power level and ASI. Numerical simulations showed that the proposed controller exhibits very fast tracking responses.

  17. Review of APR+ Level 2 PSA. Revision 2

    Energy Technology Data Exchange (ETDEWEB)

    Lehner, John R. [Brookhaven National Lab. (BNL), Upton, NY (United States); Mubayi, Vinod [Brookhaven National Lab. (BNL), Upton, NY (United States); Pratt, W. Trevor [Brookhaven National Lab. (BNL), Upton, NY (United States); Kim, Do Sam [Korea Institute of Nuclear Safety (KINS), Daejeon (Korea, Republic of); Cho, Yong Jin [Korea Institute of Nuclear Safety (KINS), Daejeon (Korea, Republic of); Cho, Sang Jin [Korea Institute of Nuclear Safety (KINS), Daejeon (Korea, Republic of); Kim, In Goo [Korea Institute of Nuclear Safety (KINS), Daejeon (Korea, Republic of)

    2012-02-17

    Brookhaven National Laboratory (BNL) assisted the Korea Institute of Nuclear Safety (KINS) in reviewing the Level 2 Probabilistic Safety Assessment (PSA) of the APR+ Advanced Pressurized Water Reactor (PWR) prepared by the Korea Hydro & Nuclear Power Co., Ltd (KHNP) and KEPCO Engineering & Construction Co., Inc. (KEPCO-E&C). The work described in this report involves a review of the APR+ Level 2 PSA submittal [Ref. 1]. The PSA and, therefore, the review is limited to consideration of accidents initiated by internal events. As part of the review process, the review team also developed three sets of Requests for Additional Information (RAIs). These RAIs were provided to KHNP and KEPCO-E&C for their evaluation and response. This final detailed report documents the review findings for each technical element of the PSA and includes consideration of all of the RAIs made by the reviewers as well as the associated responses. This final report was preceded by an interim report [Ref. 2] that focused on identifying important issues regarding the PSA. In addition, a final meeting on the project was held at BNL on November 21-22, 2011, where BNL and KINS reviewers discussed their preliminary review findings with KHNP and KEPCO-E&C staffs. Additional information obtained during this final meeting was also used to inform the review findings of this final report. The review focused not only on the robustness of the APR+ design to withstand severe accidents, but also on the capability and acceptability of the Level 2 PSA in terms of level of detail and completeness. The Korean nuclear regulatory authorities will decide whether the PSA is acceptable and the BNL review team is providing its comments for KINS consideration. Section 2.0 provides the basis for the BNL review. Section 3.0 presents the review of each technical element of the PSA. Conclusions and a summary are presented in Section 4.0. Section 5.0 contains the references.

  18. Design of a Load Following Controller for APR+ Nuclear Plants

    International Nuclear Information System (INIS)

    The load-following operation of an APR+ nuclear plants is required to restrain the adjustment of boric acid concentration and to efficiently control the control rods for the flexibility of the operation. Especially, axial flux distribution disproportion that is usually caused by load-following operation in a reactor core induces xenon oscillation because the absorption cross-section of xenon is extremely large and its effects in a reactor are delayed by the iodine precursor. Rapid and smooth power maneuvering has its benefits in view of the economical and safe operation of reactors, so it is required that the controller is efficiently designed. Therefore, the load-following operation of an APR+ nuclear plants needs the ultimate automatic control and the advanced control method that satisfies the conditions such as the flexibility, safety and convenience. A model predictive control (MPC) method is applied to design an automatic load-following controller for the integrated thermal power level and axial shape index (ASI) control for an APR+ nuclear plants. Some tracking controllers use only the current tracking command. On the other hand, since MPC considers future commands in addition to the current tracking command, the MPC can achieve better tracking performance. Therefore, the MPC has been applied very much to the control of industrial process systems. The basic concept of the MPC is to solve an optimization problem for generating finite future control inputs at current time and to implement as the current control input only the first control input among the solutions of the finite time steps. At the next time step, the second control input is not implemented and the procedure to solve the optimization problem is then repeated. The power level and the ASI are controlled by the regulating control banks and part-strength control banks together with the automatic adjustment of boric acid concentration. The 3-dimensional MASTER code, which models the APR+ nuclear

  19. La prise de décision par les patients atteints de cancer concernant leur traitement médical

    OpenAIRE

    Favrat, Deborah; Carminati, Emilie; Helou, Nancy

    2016-01-01

    Introduction : Lors du diagnostic de cancer, les patients doivent prendre des décisions quant aux traitements. Des conséquences néfastes pourraient s’en suivre car ils n’ont pas les outils en main pour y faire face et se sentent démunis. Objectif : Identifier les interventions infirmières qui favoriseraient la prise de décision des patients atteints de cancer concernant leur traitement médical à l’annonce du diagnostic. Méthode : Les bases de données sont Medline et CINHAL. Sept articles choi...

  20. Pseudomonas syringae evades host immunity by degrading flagellin monomers with alkaline protease AprA.

    Science.gov (United States)

    Pel, Michiel J C; van Dijken, Anja J H; Bardoel, Bart W; Seidl, Michael F; van der Ent, Sjoerd; van Strijp, Jos A G; Pieterse, Corné M J

    2014-07-01

    Bacterial flagellin molecules are strong inducers of innate immune responses in both mammals and plants. The opportunistic pathogen Pseudomonas aeruginosa secretes an alkaline protease called AprA that degrades flagellin monomers. Here, we show that AprA is widespread among a wide variety of bacterial species. In addition, we investigated the role of AprA in virulence of the bacterial plant pathogen P. syringae pv. tomato DC3000. The AprA-deficient DC3000 ΔaprA knockout mutant was significantly less virulent on both tomato and Arabidopsis thaliana. Moreover, infiltration of A. thaliana Col-0 leaves with DC3000 ΔaprA evoked a significantly higher level of expression of the defense-related genes FRK1 and PR-1 than did wild-type DC3000. In the flagellin receptor mutant fls2, pathogen virulence and defense-related gene activation did not differ between DC3000 and DC3000 ΔaprA. Together, these results suggest that AprA of DC3000 is important for evasion of recognition by the FLS2 receptor, allowing wild-type DC3000 to be more virulent on its host plant than AprA-deficient DC3000 ΔaprA. To provide further evidence for the role of DC3000 AprA in host immune evasion, we overexpressed the AprA inhibitory peptide AprI of DC3000 in A. thaliana to counteract the immune evasive capacity of DC3000 AprA. Ectopic expression of aprI in A. thaliana resulted in an enhanced level of resistance against wild-type DC3000, while the already elevated level of resistance against DC3000 ΔaprA remained unchanged. Together, these results indicate that evasion of host immunity by the alkaline protease AprA is important for full virulence of strain DC3000 and likely acts by preventing flagellin monomers from being recognized by its cognate immune receptor. PMID:24654978

  1. Quality Control of Concrete Structure For APR1400 Construction

    International Nuclear Information System (INIS)

    Nuclear structure shall be constructed to protect internal facilities in the normal operation against external accidents such as the radiation shielding, earthquakes and to be leak-proof of radioactive substances to the external environment in case of loss of coolants. containment and auxiliary building of nuclear power plants are built in reinforced concrete structures to maintain these protection functions. Nuclear structures shall be designed to ensure soundness in operation since they are located on the waterfront where is easy do drain the cooling water and so deterioration and damage of concrete structures caused by seawater can occur. Durability is ensured for concrete structures of APR1400, a Korea standard NPP, in compliance with all safety requirements. In particular, owners perform quality control directly on the production and pouring of cast in place concrete for the concrete structure construction to make sure concrete structures established with quality homogeneity and durability. This report is to look into the quality control standard and management status of cast in place concrete for APR1400 construction

  2. Severe Accident Management Strategy for EU-APR1400

    International Nuclear Information System (INIS)

    In EU-APR1400, the dedicated instrumentation and mitigation features for SAM are being developed to keep the integrity of containment and to prevent the uncontrolled release of fission products. In this paper, SAM strategy for EU-APR1400 was introduced in stages. It is still under development and finally the Severe Accident Management Guidance will be completed based on this SAM Strategy. Severe accidents in a nuclear power plant are defined as certain unlikely event sequences involving significant core damage with the potential to lead to significant releases according to EUR 2.1.4.4. Even though the probability of severe accidents is extremely low, the radiation release may cause serious effect on people as well as environment. Severe Accident Management (SAM) encompasses those actions which could be considered in recovering from a severe accident and preventing or mitigating the release of fission products to the environment. Whether those actions are successful or not, depending on a progression status of a severe accident to mitigate the consequences of severe accident phenomena to limit the release of radioactive materials keeping the leak tightness of the Primary Containment, and finally to restore transient severe accident progression into a controlled and safe states

  3. Analysis on the Direct Vessel Injection Line Break Accident at APR+ Standard Design

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Youngho; Yang, Huichang [TUEV Rheinland Korea Ltd., Seoul (Korea, Republic of); Kim, Kap [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2013-10-15

    APR+ (Advanced Power Reactor +) is the newest design variation of APR1400. The main characteristics of APR+, compared with APR1400, are passive safety systems and dedicated systems for severe accident mitigation. APR+ is under review for standard design certification. In this study, thermal hydraulic analysis on the Direct Vessel Injection (DVI) line break accident postulated in APR+ design was performed. Comparisons of the major parameters which can represent the overall accident behavior during DVI line break accident, several discrepancies between this study and reference data were found and such discrepancies include actuation timing of SIPs and SITs, and also include parameter behaviors of break flow rate and PCT at the accident initiation. These differences were mainly from the different thermal hydraulic models in simulation codes. The behavioral differences for break flow as well as peak cladding temperatures will be examined further as a next step for this study.

  4. Performance validation of advanced safety features of APR

    International Nuclear Information System (INIS)

    This paper briefly introduces recent progress, which is mainly being performed at KAERI, in design and performance validation tests of advanced safety features for the APR+ (Advanced Power Reactor plus). The main safety technologies included in the APR+ standard design improvement are an advanced Direct Vessel Injection Plus (DVI+), Fluidic Device Plus (FD+), and Passive Auxiliary Feedwater System (PAFS). The validation tests of advanced safety features are performed using scaled down model testes. They include: 1/5-Scale air-water test, DVI+ duct vibration test, full scale duct injection test, 1/240-Scale PAFS separate effect test, and ATLAS-PAFS integral effect test. The other design verification tests are also performed. They include: Full scale 3-Fuel assembly cross flow test, 1/5-Scale reactor flow distribution test (to be performed, under construction), Core simulator calibration developing test for core flow test, Full scale advanced Fluidic Device (FD+), CEDM test-to be performed, and IVR and core capture test. The core flow and reactor flow tests are being performed by both experimental and CFD (Computational Fluid Dynamics) analysis for the test facility development. The ECC bypass test is performed using 1/5-scale air-water test facility. The duct test facility. The 1/5-scale core barred vibration test with DVI duct is also performed under the both wet and dry condition. The design goal of PAFS is replacing an auxiliary feedwater system with a passive Steam Generator (SG) secondary cooling system of APR+. In PAFS, the core decay heat is ideogram in the Passive Condensation Cooling Tank (PCCT). The PCCT is located on the top of Auxiliary building. To validate the cooling performance of PAFS, a separate effect test loop has been constructed at KAERI (Korea Atomic Energy Research Institute), which is named PASCAL (PAFS Condensing heat removal Assessment Loop). To quantify the tube heat transfer coefficient of the horizontal heat exchanger, a full scale

  5. Écrire (d’après

    Directory of Open Access Journals (Sweden)

    Denis Saint-Amand

    2009-03-01

    Full Text Available De l’allusion à la citation, de l’emprunt criard au plagiat déguisé, les jeux d’influences et d’aller-retour avec tel ou tel modèle, grand ou mineur, ont toujours participé de l’élaboration du texte littéraire. Si l’intertextualité est sans aucun doute née en même temps que l’écriture (ou quelques minutes après et que, comme ont pu le montrer notamment Jacques-Philippe Saint-Gérand et Daniel Sangsue, les facettes multiples qu’elle déploie ont toujours suscité l’attention des hommes de lettre...

  6. Écrire (d’)après

    OpenAIRE

    Denis Saint-Amand

    2009-01-01

    De l’allusion à la citation, de l’emprunt criard au plagiat déguisé, les jeux d’influences et d’aller-retour avec tel ou tel modèle, grand ou mineur, ont toujours participé de l’élaboration du texte littéraire. Si l’intertextualité est sans aucun doute née en même temps que l’écriture (ou quelques minutes après) et que, comme ont pu le montrer notamment Jacques-Philippe Saint-Gérand et Daniel Sangsue, les facettes multiples qu’elle déploie ont toujours suscité l’attention des hommes de lettre...

  7. 14 CFR Appendix H to Part 23 - Installation of An Automatic Power Reserve (APR) System

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Installation of An Automatic Power Reserve (APR) System H Appendix H to Part 23 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT... AIRPLANES Pt. 23, App. H Appendix H to Part 23—Installation of An Automatic Power Reserve (APR) System...

  8. Pseudomonas syringae evades host immunity by degrading flagellin monomers with alkaline protease AprA

    NARCIS (Netherlands)

    Pel, Michiel J C; van Dijken, Anja J H; Bardoel, Bart W; Seidl, Michael F; van der Ent, Sjoerd; van Strijp, Jos A G; Pieterse, Corné M J

    2014-01-01

    Bacterial flagellin molecules are strong inducers of innate immune responses in both mammals and plants. The opportunistic pathogen Pseudomonas aeruginosa secretes an alkaline protease called AprA that degrades flagellin monomers. Here, we show that AprA is widespread among a wide variety of bacteri

  9. Pseudomonas syringae evades host Immunity by degrading flagellin monomers with alkaline protease AprA

    NARCIS (Netherlands)

    Pel, M.J.C.; Van Dijken, A.J.H.; Bardoel, B.W.; Seidl, M.F; Van der Ent, S.; Van Strijp, J.A.G.

    2014-01-01

    Bacterial flagellin molecules are strong inducers of innate immune responses in both mammals and plants. The opportunistic pathogen Pseudomonas aeruginosa secretes an alkaline protease called AprA that degrades flagellin monomers. Here, we show that AprA is widespread among a wide variety of bacteri

  10. Traitement des données par le logiciel SAS: introduction au module de base

    OpenAIRE

    Carletti, Isabelle; Prevot, Hugues

    2006-01-01

    Cette note constitue une introduction au module de base SAS. Après un bref aperçu de l'environnement de travail SAS et des principes du langage SAS, les étapes DATA et PROC d'un programme SAS sont exposées en plus en détails.

  11. Thermal-hydraulic Analysis of SGTR for Supporting PSA in APR+

    International Nuclear Information System (INIS)

    The Advanced Power Reactor Plus (APR+) is being developed in Korea. To enhance the safety of the APR+, a passive auxiliary feedwater system (PAFS) has been adopted in the APR+. The PAFS completely replaces the conventional active auxiliary feedwater system (AFWS). It is operated by a natural driving force mechanism when demanding auxiliary feedwater. It could maintain the system function of cooling the primary side and remove the decay heat while operated PAFS. For estimating the safety of APR+ design, the probabilistic safety assessment (PSA) of APR+ is performed. As the PAFS replaces the conventional AFWS, it is required to verify the cooling capacity of PAFS for the accurate evaluation. For this reason, this paper discusses the cooling performance of the PAFS while transient accidents

  12. An ATWS Analysis for EU-APR1400 Following the European Utility Requirement

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Minshin; Lee, Cheolshin; Sohn, Jongjoo [KEPCO Engineering and Construction Company., Inc., Daejeon (Korea, Republic of)

    2013-05-15

    This paper presents the results of the evaluation of the ATWS events with respect to Reactor Coolant System (RCS) overpressure and re-criticality for the European APR1400 (EU-APR1400) according to European Utility Requirement (EUR). This paper evaluates the ATWS impact on the EU-APR1400 by applying EUR. Based on the results of safety analysis for ATWS events, all the acceptance criteria for EUR can be satisfied due to the proper functioning of ATWS mitigation systems. However the four events are investigated only in this paper, and hence the results of this paper can not be concluded that the EU-APR1400 design satisfy all requirements for the EUR. Therefore, a further study for all Design Basis Event Category 2 (DBC2) events with ATWS needs to be performed in order to assess the comprehensive impact of ATWS events for the EU-APR1400 design.

  13. Procédé intégré de traitement du gaz naturel Integrated Process for Natural Gas Treatment

    Directory of Open Access Journals (Sweden)

    Larue J.

    2006-11-01

    Full Text Available L'Institut français du pétrole a développé une nouvelle technique de traitement du gaz naturel, le procédé intégré IFPEXOL, basé sur une nouvelle mise en oeuvre de méthanol à basse température, qui incorpore dans un procédé unique les trois fonctions de déshydratation, extraction des liquides de gaz naturel (LGN et désacidification. Le procédé IFPEXOL se compose de deux sections successives : une première section IFPEX-1 de déshydratation et d'extraction des LGN, une deuxième section IFPEX-2 de désacidification si nécessaire. Pour chaque section, l'influence des paramètres principaux sur les performances du procédé est examinée. Après un programme de recherche et développement au laboratoire et sur une unité pilote, le procédé IFPEXOL a été industrialisé. La première unité IFPEX-1 a démarré en juin 1992 au Canada sur le champ d'East Gilby en association avec Petro-Canada; par la suite, 11 autres unités IFPEX-1, dont 7 sont en opération, ont été vendues. La section IFPEX-2 est en cours de commercialisation. The Institut français du pétrole has developed a new natural gas treatment technique, the integrated IFPEXOL process, based on the use of methanol at low temperature, and which includes 3 functions in only one step : dehydration, NGL recovery and acid gases removal. The IFPEXOL process is split into two successive sections : IFPEX-1 removes NGL and water, IFPEX-2 removes the acid gases when necessary. For each section, the influence of the main parameters on the process performances is examined. After a research and development program at laboratory scale and on a pilot plant, the IFPEXOL process has reached the industrial step. The first IFPEX-1 unit has started up in June 1992 in Canada at Petro-Canada's East Gilby field. Subsequently, 11 other units, of which 7 are running, have been licenced. The results obtained from the industrial plants confirm the simulation models. The IFPEX-2 section is in

  14. Les expressions idiomatiques: description théorique et traitement dictionnairique: (l'exemple des dictionnaires monolingues français

    Directory of Open Access Journals (Sweden)

    Gregor Perko

    2005-12-01

    Full Text Available Le present article se propose d'examiner le traitement des expressions idiomatiques dans un corpus de plusieurs dictionnaires monolingues du francais en un volume et de suggerer quelques ameliorations de ce traitement. L 'accent est mis tout particulierement sur les besoins specifiques d 'un utilisateur etranger. Avant d 'entamer une analyse lexicographique proprement dite, il nous semble indispensable de faire le point sur le statut linguistique des expressions idiomatiques et d 'en proposer une typologie.

  15. Development of Core Simulator (CoSi) for APR1400 And Analysis of LPPT Result using APR1400-CoSi

    Energy Technology Data Exchange (ETDEWEB)

    Moon, Sang-Rae; Kim, Yong-Bae; Lee, Eun-Ki [KHNP-CRI, Daejeon (Korea, Republic of)

    2014-10-15

    According to NRC guidelines, Low Power Physics Test (LPPT) is required to be performed in low temperature/low pressure (160 .deg. C/42.2 kg/cm{sup 2}) as well as NOT/NOP (291.3 .deg. C/158.2 kg/cm{sup 2}) because Shin-Kori Unit 3 is FOAK nuclear power plant. Low Power Physics Test (LPPT) is essential to verify the nuclear design and robustness of reactor safety. LPPT consists of initial criticality, Point of Adding Heat (POAH), All Rod Out (ARO) Boron Concentration, Isothermal Temperature Coefficient (ITC), Control Rod Worth measurements and so on. KHNP-CRI has developed the Core Simulator for APR1400 (APR1400-CoSi) in order to improve the ability performing the LPPT. Especially, APR1400-CoSi has enhanced capability to calculate the full Core neutronic parameters by revising RAST-K that is three dimensional real time core kinetic program. APR1400-CoSi has been developed for education-training of Low Power Physics Test(LPPT). Particularly, APR1400-CoSi has an enhanced capability to calculate the full core neutronic parameters by revising RAST-K which is a three dimensional real time core kinetics program. Low Power Physics Test (LPPT) was performed using APR1400-CoSi and the results showed very similar values with the predicted ones. In other words, the initial core model of Shin-Kori Unit 3 in APR1400-CoSi system has been verified to be appropriate enough. Also, it was confirmed that the test range of Low Power Physics Test (LPPT) reamains effective even though the largest incremental bank reactivity is inserted in core by analyzing the power change during the rod SWAP test.

  16. Development of Core Simulator (CoSi) for APR1400 And Analysis of LPPT Result using APR1400-CoSi

    International Nuclear Information System (INIS)

    According to NRC guidelines, Low Power Physics Test (LPPT) is required to be performed in low temperature/low pressure (160 .deg. C/42.2 kg/cm2) as well as NOT/NOP (291.3 .deg. C/158.2 kg/cm2) because Shin-Kori Unit 3 is FOAK nuclear power plant. Low Power Physics Test (LPPT) is essential to verify the nuclear design and robustness of reactor safety. LPPT consists of initial criticality, Point of Adding Heat (POAH), All Rod Out (ARO) Boron Concentration, Isothermal Temperature Coefficient (ITC), Control Rod Worth measurements and so on. KHNP-CRI has developed the Core Simulator for APR1400 (APR1400-CoSi) in order to improve the ability performing the LPPT. Especially, APR1400-CoSi has enhanced capability to calculate the full Core neutronic parameters by revising RAST-K that is three dimensional real time core kinetic program. APR1400-CoSi has been developed for education-training of Low Power Physics Test(LPPT). Particularly, APR1400-CoSi has an enhanced capability to calculate the full core neutronic parameters by revising RAST-K which is a three dimensional real time core kinetics program. Low Power Physics Test (LPPT) was performed using APR1400-CoSi and the results showed very similar values with the predicted ones. In other words, the initial core model of Shin-Kori Unit 3 in APR1400-CoSi system has been verified to be appropriate enough. Also, it was confirmed that the test range of Low Power Physics Test (LPPT) reamains effective even though the largest incremental bank reactivity is inserted in core by analyzing the power change during the rod SWAP test

  17. Arrêt des traitements et idéologies thérapeutiques du cancer

    OpenAIRE

    Mino, Jean-Christophe; Cohen-Solal, Zoé; Kentish-Barnes, Nancy

    2016-01-01

    En France, la majorité des décès des personnes atteintes de cancer se déroulent à l’hôpital. A partir d’entretiens approfondis avec 18 médecins cancérologues hospitaliers, cet article explore la manière dont ceux-ci conçoivent l’arrêt des traitements et les soins de fin de vie. Alors que tous les praticiens se disent confrontés au poids de la décision d’arrêt et à la complexité du travail en équipe, l’analyse permet de distinguer deux grands types de discours. Ceux-ci renvoient à deux catégor...

  18. Contributions au traitement statistique du signal avec des applications biomédicales

    OpenAIRE

    Nguyen, Quang Thang

    2012-01-01

    Cette étude présente des contributions en traitement statistique du signal avec des applications biomédicales. La thèse est divisée en deux parties. La première partie traite de la détection des hotspots à l'interface des protéines. Les hotspots sont les résidus dont les contributions énergétiques sont les plus importantes dans l'interaction entre protéines. Les forêts aléatoires (Random Forests) sont utilisées pour la classification. Une nouvelle famille de descripteurs de hotspot est égalem...

  19. Traitement statistique des distorsions non-linéaires pour la restauration des enregistrements sonores.

    OpenAIRE

    Picard, Guillaume

    2006-01-01

    L'objet de la thèse est l'étude, la modélisation et le traitement des distorsions non linéaires sonores, pour lesquelles les techniques actuelles s'avèrent impuissantes. L'approche retenue consiste à représenter, globalement, à la fois le signal audio à restaurer et le processus de distorsion, dans le cadre d'un modèle statistique. Cette approche présente un bon compromis entre une souhaitable généricité -possibilité de traiter à l'aide d'une méthode globale plusieurs types de distorsions- et...

  20. Approches spatiales cyclostationnaires pour le traitement des interférences en radioastronomie

    OpenAIRE

    Hellbourg, Gregory; Weber, Rodolphe; Capdessus, Cécile; Boonstra, Albert-Jan; Feliachi, Rym

    2011-01-01

    L'environnement électromagnétique est de plus en plus envahi par les activités de télécommunications, limitant ainsi la sensibilité et les performances des radiotélescopes. Il devient donc nécessaire de développer des traitements efficaces afin de limiter l'impact de ces interférences radioélectriques (RFI). A ce titre, l'exploitation de la propriété de cyclostationnarité, inhérente à la plupart des signaux de télécommunication, est une piste de développement prometteuse pour la radioastronom...

  1. Le traitement de l’idéologie dans la sociologie de Luc Boltanski

    Directory of Open Access Journals (Sweden)

    David Vrydaghs

    2006-10-01

    Full Text Available IntroductionLe concept d’idéologie apparaît dans la sociologie de Luc Boltanski à partir du Nouvel Esprit du capitalisme, publié en 1999. L’auteur y revient dans La Condition fœtale, paru en 2004. On aurait donc pu se contenter de ces ouvrages pour examiner le traitement réservé à l’idéologie dans la sociologie de Luc Boltanski. On préférera pourtant revenir aux travaux antérieurs du sociologue, et ce pour deux raisons.D’abord parce que le concept d’idéologie tel qu’il est employé dans Le Nou...

  2. Alternatives aux traitements anthelminthiques en élevage biologique des ruminants

    OpenAIRE

    Hoste, Hervé; Cabaret, Jacques; Grosmond, G.; Guitard, J.-P.

    2009-01-01

    En termes de gestion sanitaire des troupeaux, les recommandations du règlement de la commission européenne du 5 septembre 2008 (CE 889/2008), remplaçant le REPAB, visent à restreindre le recours aux traitements chimiques pour gérer les pathologies. Elles privilégient en contre-partie les règles d’hygiène et le développement de la réponse immune de l’animal. Ces principes généraux se retrouvent et sont illustrés dans la gestion du parasitisme helminthique par les strongles gastro-intestinaux q...

  3. De la pathologie au traitement : la gestion municipale de l'islam en Belgique

    OpenAIRE

    MANÇO, Ural; KANMAZ, Meryem

    2004-01-01

    La Belgique passe pour être le pays européen le plus avancé en matière de reconnaissance officielle du culte islamique. L'objectif de cette contribution est de montrer, au départ du traitement municipal de l'islam, que cette reconnaissance est, au contraire, lacunaire. Dès les années 1970, des municipalités, confrontées à une présence de musulmans sur leur territoire, ont dû faire face à un vide politico-légal laissé par l'Etat belge en prenant des décisions parfois arbitraires dans de...

  4. Implementation of Low Boron Core for APR1400 Initial Cycle

    International Nuclear Information System (INIS)

    Low boron capability of a nuclear power plant is rather a qualitative specification requiring the nuclear power plant to be shut down by control rods alone at any time of a plant cycle according to EUR. The reduction of soluble boron is beneficial since it gives the reduction of the corrosive effects in the plant system and improves plant safety giving more negative MTC. Thus, it is necessary to reduce the amount of soluble boron for the criticality to achieve the low boron capability. However, the reduction of soluble boron has its own set of specific challenges that must be overcome. There are two methods to enable the reduction of soluble boron without modifying plant system significantly. The goal of this study is to investigate the loading pattern to achieve the soluble boron reduction for Shin-Kori Unit 5 APR1400 initial core using the low and high content gadolinia burnable absorbers with standard fuel rod enrichment and to verify the feasibility of low boron core with conventional gadolinia burnable absorbers only. For this study, KARMA has been employed to solve 2-D Transport equation, and ASTRA is used for full core analysis. It was possible to achieve the low boron core for APR1400 Cycle 1 using extended usage of two types of gadolinia burnable absorbers sacrificing fuel cycle economy a little bit while enhancing plant safety significantly. Gd rod patterns within an assembly were optimized through geometrical weighting and loading pattern was developed based on these patterns. The amount of soluble boron reduction achieved is 45.4%. The improvement in plant safety is significant resulting in the reduction of least negative best-estimate MTC by about 4 pcm. Also shutdown margin is increased slightly for low boron core. However, the behavior of axial power shape turns out to be undesirable showing a relatively large fluctuation caused by the more negative MTC. It was found that the low boron core might impose kind of operational difficulty. It is usually

  5. Extended Station Blackout Coping Capabilities of APR1400

    Directory of Open Access Journals (Sweden)

    Sang-Won Lee

    2014-01-01

    Full Text Available The Fukushima Dai-ichi nuclear power plant accident shows that an extreme natural disaster can prevent the proper restoration of electric power for several days, so-called extended SBO. In Korea, the government and industry performed comprehensive special safety inspections on all domestic nuclear power plants against beyond design bases external events. One of the safety improvement action items related to the extended SBO is installation of external water injection provision and equipment to RCS and SG. In this paper, the extended SBO coping capability of APR1400 is examined using MAAP4 to assess the effectiveness of the external water injection strategy. Results show that an external injection into SG is applicable to mitigate an extended SBO scenario. However, an external injection into RCS is only effective when RCS depressurization capacity is sufficiently provided in case of high pressure scenarios. Based on the above results, the technical basis of external injection strategy will be reflected on development of revised severe accident management guideline.

  6. APR+ PAFS Cooling Performance Analysis using RELAP5

    International Nuclear Information System (INIS)

    To enhance safety and reliability of nuclear power plant in domestic industry, passive safety system design has been introducing. Especially, passive auxiliary feedwater system (PAFS) has been applied to the advanced power reactor plus (APR+). PAFS is a facility that replaces an active auxiliary feedwater system (AFWS) in the existing plant. The system function is to remove the generating heat of primary system during transient and accidents unless main feedwater system is available. PAFS consists of a passive condensate cooling tank (PCCT), a heat exchanger, valves, and pipes as shown in Fig. 1. PAFS design is considered that its performance ensure the safety function. But it is difficult that the performance of PAFS is determined quantitatively unlike AFWS. Because AFWS can be controlled on its flow and enthalpy but PAFS can't be controlled on them. The characteristic of passive safety system can be changed along transient and accident. Therefore some considerations are required about how to determine the PAFS performance and how to find the conservative condition to evaluate it in respect to transient and accidents

  7. Conceptual design of passive containment cooling system based on APR+

    International Nuclear Information System (INIS)

    The accident of the Fukushima nuclear power plant left a profound message toward the need for a passive cooling system which can operate under the extended station blackout. These days, nuclear institutions in Korea are developing Advanced Power Reactor Plus (APR+). Its distinct characteristic lies on the passive auxiliary feed water system (PAFS) which removes decay heat to a passive condensation cooling tank (PCCT) by natural convection. Though the system is expected to work well under station blackout, the system becomes useless under the loss of coolant accident (LOCA) combined with station blackout. This paper aims at using existing heat exchangers of PAFS and PCCT under LOCA to cool the reactor as well as the containment in a fully passive way. To enhance the condensation rate of heat exchangers in PCCT, we need to produce convective flow in the PCCS heat exchangers. Therefore, the whole region of the concrete containment is divided into 3 chambers: inner, outer, PCCS chambers. An outer chamber is disposed to collect non-condensable gas. The condensate is stored in a condensate storage tank (CST) and injected into the reactor by gravity. This system makes a closed circuit to work indefinitely. A scoping analysis for the containment pressure is performed as a function of various parameters: outer chamber volume and number of tubes in heat exchangers. (author)

  8. Modal analysis of an ECC duct for APR+ reactor barrel

    International Nuclear Information System (INIS)

    Advanced Power Reactor Plus (APR+) provides four Direct Vessel Injection (DVI) ducts on the reactor barrel to enhance the performance of Emergency Core Cooling System (ECCS). Several studies on safety analysis have verified the excellent performance of the DVI duct. In this study, from the viewpoint of mechanical integrity, modal analyses of two full-scaled DVI ducts have been presented; both numerical analysis and modal tests have been performed in air and water. It was found that the numerical simulation and modal test coincide with each other. The DVI duct is a thin shell of 5 mm thickness, so that harmonic responses to RCP blade passing frequencies should be checked. The dominant passing frequencies are known to be 20, 40, 60, 120 and 240 Hz. In addition, an interesting thing in this study is that added mass effect by coolant seems to be so significant that the natural frequency of the ducts under water could be considerably low as compared with those in air; the natural frequency under water is 60 % lower than that in air. (author)

  9. Verification of SAMG entry condition for APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Yun, Junghyun; Kim, Taewan; Kim, Jonghyun [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

    2013-10-15

    In the wake of the Fukushima accident, severe accident management has become important more than ever. While Emergency Operating Procedures (EOPs) focuses on cooling down the core during a design basis accident, the prime objective of severe accident management guideline (SAMG) is to prevent the release of radioactive material into the environment during a severe accident. Only one fixed value of core exit temperature (CET) has been applied for several decades to different types of nuclear power plants (NPPs) in Korea. Although the different types of NPPs have different cladding materials and system designs, the identical CET, i. e., 650 .deg. C, is applied as the entry condition to the SAMG of all the NPPs (except CANDU plants), i. e., Westinghouse type, OPR1000, and APR1400. In this paper, the transition point is re-evaluated for dominant severe accident sequences; station black-out (SBO), small break loss of coolant accident (SBLOCA), and me dium break loss of coolant accident (MBLOCA). In cases of SBO and SBLOCA, the current SAMG entry condition seems proper, while it needs to be reconsidered for MBLOCA case.

  10. APR+ PAFS Cooling Performance Analysis using RELAP5

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Kyung Jin; Hong, Soon Joon [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2011-05-15

    To enhance safety and reliability of nuclear power plant in domestic industry, passive safety system design has been introducing. Especially, passive auxiliary feedwater system (PAFS) has been applied to the advanced power reactor plus (APR+). PAFS is a facility that replaces an active auxiliary feedwater system (AFWS) in the existing plant. The system function is to remove the generating heat of primary system during transient and accidents unless main feedwater system is available. PAFS consists of a passive condensate cooling tank (PCCT), a heat exchanger, valves, and pipes as shown in Fig. 1. PAFS design is considered that its performance ensure the safety function. But it is difficult that the performance of PAFS is determined quantitatively unlike AFWS. Because AFWS can be controlled on its flow and enthalpy but PAFS can't be controlled on them. The characteristic of passive safety system can be changed along transient and accident. Therefore some considerations are required about how to determine the PAFS performance and how to find the conservative condition to evaluate it in respect to transient and accidents

  11. Study on Maintenance Personnel Development Plan For The Exported APR1400 Commissioning

    International Nuclear Information System (INIS)

    This paper indicates ways to develop maintenance personnel for the exported APR1400 commissioning. The exported APR1400 has not been experienced ay maintenance yet, and requirements for maintenance personnel have not been clarified yet. Based on sound maintenance experience, KEPCO Plant Service and Engineering Company (KEPCO KPS) has studied on maintenance training and career requirement to establish a development plan of the maintenance personnel for the exported nuclear power plant. By defining manpower and training requirement, and mobilization plan, we expect to secure reliability of the exported APR1400

  12. Résultats positifs de traitements de prévention de venues d'eau en Russie Successful Application Cases of Water Control Treatments in Russia

    Directory of Open Access Journals (Sweden)

    Kolher N.

    2006-11-01

    'hydrocarbures. Les résultats de quelques traitements de puits réalisés en Russie en 1993 sont présentés ci-après dans cet article. Water encroachment in oil or gas producing wells is generally responsible for both a rapid productivity decline and an increase in operating costs caused by the handling and treating of large quantities of water. It also induces some secondary problems such as fines or sand production, corrosion and scale deposits. The result is often a premature shut-in of these wells because production has become uneconomic. To face these problems and to extend the lifetime of the wells, some companies have tried to inject cements, resins or either organic or inorganic strong gels into the water producing intervals. These impermeable barriers, which require zone isolation for their placement, aim to stop the flow of all fluids. These treatments are nevertheless very risky if the oil and water bearing zones are not easily distinguishable or if the completion of the candidate well does not allow zone isolation. To overcome these problems studies were performed since 1984 in IFP's lab in order to develop systems able to reduce selectively water production without affecting in a great extent the flow of hydrocarbons. These systems are based on the use of either single highmolecular-weight water soluble polymers or of weak gels obtained from these polymers in the presence of some X-linking additives. Several processes have been developed, each of them adapted to the specific reservoir characteristics of bottom-hole temperature and produced brine salinity. All these processes have the advantage to reduce selectively the permeability to brine while maintaining or even improving the production of hydrocarbons. This paper presents the results of some well tests conducted in Russia in 1993.

  13. J’ai mal au dos: mon physio me fait marcher : de la marche comme traitement de la lombalgie chronique

    OpenAIRE

    Auzet, Pierre; Vallon, Thomas; Christe, Guillaume

    2016-01-01

    Introduction : La lombalgie chronique est la pathologie musculosquelettique la plus fréquente et la plus incapacitante. Elle appelle une compréhension biopsychosociale et une prise en charge multidisciplinaire. Parmi les recommandations, il est primordial de rester actif. La marche, comme moyen simple, sécuritaire et global de pratiquer l’activité physique, pourrait être un traitement pertinent de la lombalgie chronique. Objectif : Réaliser une revue narrative évaluant les effets de la marche...

  14. Current status of integrated HFE V and V system of APR1400

    International Nuclear Information System (INIS)

    The first Advanced Light Water Reactor called Advanced Power Reactor (APR1400) has many specific features such as passive safety features, digital I and C, and digitalized main control room design. This digital-based neo-concept main control room design needs comprehensive verification and validation process to get the license for construction. An integrated system for APR1400 MMIS design validation is under development by KEPRI with the participating of KHNP. The facility which is based on the NUREG/CR-6393 and ANS3.5 can simulate all of the dynamic functions and responses of APR1400, and measure the human factors by using conventional subject methods and measuring the operator's biological signals. This system will be used in human factors V and V process of the PRM (NUREG0711) of APR1400 MMIS design. (authors)

  15. Development of human factors validation system for the advanced control room of APR1400

    International Nuclear Information System (INIS)

    A human factors validation system for the main control room (MCR) of Advanced Power Reactor 1400 MWe (APR1400) has been developed as it adopts digitalized human-system interfaces (HSIs). The integrated validation system is composed of process/plant models, HSIs, and the human performance evaluation support system (HUPESS). A real-time thermal-hydraulic code, RELAP5 R/T, was used and modified to simulate the dynamic characteristics of the APR1400, and simulation software, 3KeyMaster, was used to model the balance of plant systems. The HSIs developed in this study include all facilities in the APR1400 MCR, such as large display panels, 3 identified operator workstations, and a safety console. In addition, the remote shutdown workstation has been developed. The display systems in the HSIs have been developed using ProcSee, which is a software tool for developing and displaying dynamic graphical user interfaces. This paper describes the configurations of HSIs including display systems, the dynamic models of the APR1400 simulator, the instructor station, and the HUPESS. This paper also presents the results of plant simulation performance tests at transient compared with the results of RELAP5/MOD3.3 calculations. The human factors validation system for the advanced control room of APR1400 provides high degrees of physical, functional, and dynamic fidelities, and can be used in the validation process of the APR1400 HSI design. (author)

  16. Reliability enhancement of APR + diverse protection system regarding common cause failures

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Y. G.; Kim, Y. M.; Yim, H. S. [KEPCO Engineering and Construction Company, Inc., 1045 Daedeok-Daero, Yuseong-gu, Daejeon 305-353 (Korea, Republic of); Lee, S. J. [Chungnam National Univ., 99 Daehak-ro, Yuseong-gu, Daejeon 305-764 (Korea, Republic of)

    2012-07-01

    The Advanced Power Reactor Plus (APR +) nuclear power plant design has been developed on the basis of the APR1400 (Advanced Power Reactor 1400 MWe) to further enhance safety and economics. For the mitigation of Anticipated Transients Without Scram (ATWS) as well as Common Cause Failures (CCF) within the Plant Protection System (PPS) and the Emergency Safety Feature - Component Control System (ESF-CCS), several design improvement features have been implemented for the Diverse Protection System (DPS) of the APR + plant. As compared to the APR1400 DPS design, the APR + DPS has been designed to provide the Safety Injection Actuation Signal (SIAS) considering a large break LOCA accident concurrent with the CCF. Additionally several design improvement features, such as channel structure with redundant processing modules, and changes of system communication methods and auto-system test methods, are introduced to enhance the functional reliability of the DPS. Therefore, it is expected that the APR + DPS can provide an enhanced safety and reliability regarding possible CCF in the safety-grade I and C systems as well as the DPS itself. (authors)

  17. Reliability enhancement of APR + diverse protection system regarding common cause failures

    International Nuclear Information System (INIS)

    The Advanced Power Reactor Plus (APR +) nuclear power plant design has been developed on the basis of the APR1400 (Advanced Power Reactor 1400 MWe) to further enhance safety and economics. For the mitigation of Anticipated Transients Without Scram (ATWS) as well as Common Cause Failures (CCF) within the Plant Protection System (PPS) and the Emergency Safety Feature - Component Control System (ESF-CCS), several design improvement features have been implemented for the Diverse Protection System (DPS) of the APR + plant. As compared to the APR1400 DPS design, the APR + DPS has been designed to provide the Safety Injection Actuation Signal (SIAS) considering a large break LOCA accident concurrent with the CCF. Additionally several design improvement features, such as channel structure with redundant processing modules, and changes of system communication methods and auto-system test methods, are introduced to enhance the functional reliability of the DPS. Therefore, it is expected that the APR + DPS can provide an enhanced safety and reliability regarding possible CCF in the safety-grade I and C systems as well as the DPS itself. (authors)

  18. Facteurs prédictifs de l’échec du Traitement Préventif Intermittent du paludisme à la sulfadoxine – pyriméthamine (TPIp-SP) dans une population de femmes enceintes à Yaoundé

    Science.gov (United States)

    Essiben, Félix; Foumane, Pascal; de Nguefack, Marcelle Aurelie Tsafack; Eko, Filbert Eko; Njotang, Philip Nana; Enow, Robinson Mbu; Mboudou, Emile Telesphore

    2016-01-01

    Introduction Le traitement préventif intermittent à la sulfadoxine-pyriméthamine (TPIp-SP) est recommandé pour prévenir le paludisme pendant la grossesse. Nous avons recherché les facteurs associés à l’échec de cette stratégie. Méthodes Nous avons mené une étude cas - témoins dans deux formations sanitaires de Yaoundé, du 1er Mai 2014 au 30 Avril 2015. Les femmes enceintes sous TPIp-SP hospitalisées pour paludisme ayant un Test de Diagnostic Rapide (TDR) positif (cas) étaient comparées aux femmes enceintes sous TPIp-SP ayant un TDR négatif (témoins). Les logiciels Epi info 7 et SPSS 18.0 ont été utilisés avec P < 0,05 comme seuil de significativité. Résultats Nous avons recruté 234 sujets, 109 cas (46,6%) et 125 témoins (53,4%). Les facteurs associés retrouvés étaient: la primiparité (P=0,03; OR=1,15; IC= 0,32 - 4,10), la non utilisation de la MILDA (P=0,006; OR= 2,31; IC= 1,26 - 4,25), un antécédent d'hospitalisation pour paludisme (P=0,007; OR= 2,19; IC= 1,23 - 3,89), le début de la TPIp-SP après la 28ème semaine de grossesse (P=0,001, OR= 3,55; IC= 1,7 - 7,61). Après régression logistique, la primiparité (P=0,024; OR=2,01; IC=1,1-3,7) et un antécédent d'hospitalisation pour paludisme (P=0,001; OR=2,83; IC=1,50-5,4) restaient associés à l’échec du TPIp-SP. Conclusion Un antécédent d'hospitalisation pour accès palustre et la primiparité sont des facteurs prédictifs indépendants de l’échec de la TPIp-SP. PMID:27303570

  19. Engineering and Directed Evolution of a Ca2+ Binding Site A-Deficient AprE Mutant Reveal an Essential Contribution of the Loop Leu75–Leu82 to Enzyme Activity

    Directory of Open Access Journals (Sweden)

    Eliel R. Romero-García

    2009-01-01

    Full Text Available An aprE mutant from B. subtilis 168 lacking the connecting loop Leu75–Leu82 which is predicted to encode a Ca2+ binding site was constructed. Expression of the mutant gene (aprEΔLeu75–Leu82 produced B. subtilis colonies lacking protease activity. Intrinsic fluorescence analysis revealed spectral differences between wild-type AprE and AprEΔL75–L82. An AprEΔL75–L82 variant with reestablished enzyme activity was selected by directed evolution. The novel mutations Thr66Met/Gly102Asp located in positions which are predicted to be important for catalytic activity were identified in this variant. Although these mutations restored hydrolysis, they had no effect with respect to thermal inactivation of AprEΔL75–L82  T66M  G102D. These results support the proposal that in addition to function as a calcium binding site, the loop that connects β-sheet e3 with α-helix c plays a structural role on enzyme activity of AprE from B. subtilis 168.

  20. Economics enhancement of APR1400 through the application of new construction methods

    International Nuclear Information System (INIS)

    The development of APR1400 (formerly KNGR) project is one of Korea's national G-7 projects, sponsored by the government and KHNP (Korea Hydro and Nuclear Power Co., Ltd.). APR1400, an evolutionary standard reactor with a thermal output of 4000MWt, upgrades the safety and economic competitiveness of nuclear power, incorporating cutting-edge advanced technologies, while standing on the proven experience of Optimized Power Reactor 1000(OPR1000, formerly KSNP) design. APR1400 has been adopted as the design for Shin-Kori Units 3 and 4. APR1400 development project consisted of three phases in order to check and make only necessary adjustments at the end of each phase and the standard design certification (DC) was issued in May 2002. The project set up the top-tier requirements for the design's safety, economy, operability, maintainability, and construct ability in the earliest design stage. The requirements have been evaluated periodically during the design process, and the results of each evaluation were reflected in the final design. Shin-Kori Units 3 and 4 are the first APR1400 projects, and will be built near the Kori NPP site, where four units are currently in operation and two OPR1000 (Improved Korean Standard Nuclear Power Plant) units called Shin-Kori Units 1 and 2 are under construction. Shin-Kori Units 3 and 4 will be constructed based on APR1400 standardized design, while incorporating the site characteristics and construction and operation experiences of OPR1000. This paper describes new construction methods to improve economics and construct ability of APR1400 to meet the target schedule, which is set to 41.5 months from the first concrete pouring to the fuel loading for the Nth plant. The new construction methods consist of 'Open Top Method' for installation of major NSSS equipment, 'Large Modularization' for the Building Structures, Reactor Vessel Internals and Major Components and deck plate method, etc

  1. Analyse temps-frequence et traitement des signaux RSO à haute résolution spatiale pour la surveillance des grands ouvrages d'art

    OpenAIRE

    Andrei ANGHEL

    2015-01-01

    Cette thèse s'articule autour de deux axes de recherche. Le premier axe aborde les aspects méthodologiques liés au traitement temps-fréquence des signaux issus d'un radar FMCW (à onde continue modulée en fréquence) dans le contexte de la mesure des déplacements fins. Le second axe est dédié à la conception et à la validation d'une chaîne de traitement des images RSO (radar à synthèse d'ouverture) satellitaire. Lorsqu'un maillage 3D de la structure envisagée est disponible, les traitements pro...

  2. Experimental and MARS code simulation of DVI line 25% and 50% break LOCAs using SNUF for APR1400

    International Nuclear Information System (INIS)

    APR1400, is an evolutionary PWR (Pressurized Water Reactor) based on the well-proven OPR1000 design. The APR1400 has adopted DVI (Direct Vessel Injection) system instead of CLI (Cold Leg Injection) system as advanced safety features of ECCS (Emergency Core Cooling System). The configuration of the improved ECCS in the APR1400 is completely different from that in the OPR1000 in which pipes for the safety water injection are connected to the cold leg. In APR1400, the safety water injection pipes are directly connected to the RPV (Reactor Pressure Vessel). Thus, the safety water injection system in the APR1400 is called the DVI (Direct Vessel Injection) system. Moreover, safety water injections by the HPSI (High Pressure Safety Injection) pumps are mechanically separately in the APR1400.

  3. Les effluents vinicoles : problématique du traitement et premier bilan sur la conception et le fonctionnement des procédés biologiques

    OpenAIRE

    Racault, Y.; Stricker, A.E.; Vedrenne, J.

    2002-01-01

    Une large gamme de procédés de traitement est désormais applicable aux effluents vinicoles et une méthodologie propre à ce type d'effluents est nécessaire pour choisir la solution la plus adaptée en fonction des contraintes (caractéristiques des rejets, qualité requise pour les eaux traitées, environnement, capacités de stockage in situ...). Les spécificités de fonctionnement des traitements biologiques appliqués aux effluents vinicoles sont rappelées ainsi que les performances possibles. Une...

  4. Traitement hormonal de la ménopause et risque de diabète chez les femmes de la cohorte E3N

    OpenAIRE

    de Lauzon-Guillain, Blandine; Fournier, Agnès; Fabre, Alban; Simon, Nicolas; Mesrine, Sylvie; Boutron-Ruault, Marie-Christine; Balkau, Beverley; Clavel-Chapelon, Françoise

    2009-01-01

    International audience Deux essais randomisés américains ont mis en évidence une diminution du risque de diabète chez les femmes qui prenaient un traitement hormonal de la ménopause. L'objectif de ce projet est de voir si ces résultats sont applicables à la population française, où les traitements sont différents de ceux utilisés aux États-Unis

  5. Traitement syllabique en lecture chez des enfants sourds : effet du Langage Parlé Complété

    OpenAIRE

    PAIRE-FICOUT,L; Magnan, A.

    2001-01-01

    Une adaptation visuelle du paradigme de Mehler et al. (1981) est utilisée pour comparer le traitement de l'unité syllabique en lecture de mots isolés chez six enfants sourds pratiquant le LPC (système manuel qui permet de compléter l'information labiale) et six enfants sourds sans LPC. Les enfants doivent indiquer si une cible visuelle de deux ou trois lettres de structure syllabique CV ou CVC se trouve à l'initiale d'un mot (par exemple la cible BA ou BAL est présentée avant le mot BALADE ou...

  6. Traitement du foisonnement filamenteux dû à Microthrix parvicella par ajout de sels métalliques

    OpenAIRE

    Durban, N.; Juzan, L.; Krier, J.; Héduit, A.; Gillot, S.

    2012-01-01

    / Les dysfonctionnements biologiques dus au développement de bactéries filamenteuses posent de nombreux problèmes d’exploitation aux stations d'épuration du type boues activées. Le filament le plus souvent mis en cause dans ce type de dysfonctionnement en France est Microthrix parvicella. La solution curative la plus utilisée actuellement est la chloration, traitement efficace mais non spécifique, qui impacte également la biologie des boues activées. Une solution émergente consiste à ut...

  7. Chemical treatment of uranium ores in France; Le traitement chimique des minerais d'uranium en France

    Energy Technology Data Exchange (ETDEWEB)

    Mouret, P.; Sartorius, R. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    The various processes of chemical treatmenturanium ores, from the oldest to the more recent, are exposed, considering the following conditions: economics, geography, techniques and safety. The interest of obtaining a final concentrate as uranyl nitrate is discussed. (author)Fren. [French] Les differents procedes de traitement chimique des minerais uraniferes sont exposes depuis les premiers jusqu'aux plus recents, en tenant compte des facteurs economiques, geographiques, techniques et de salubrite. L'interet d'obtenir un concentre final a l'etat de nitrate d'uranyle est discute. (auteur)

  8. Techniques d'automatique et de traitement du signal pour l'asservissement visuel et la perception auditive en robotique

    OpenAIRE

    Danès, Patrick

    2010-01-01

    Les travaux présentés dans ce manuscrit d'Habilitation à Diriger des Recherches concernent essentiellement un ensemble de primitives du niveau fonctionnel de la Robotique, dont les fondements scientifiques sont ancrés dans l'Automatique et le Traitement du Signal. Bien plus qu'un domaine d'application de théories développées par ailleurs, la Robotique, par ses spécificités ou ses contraintes, " questionne " souvent l'état de l'art en Automatique et Signal, voire exige des extensions méthodolo...

  9. Traitements temps réel en codage source et canal pour des Communications hertziennes et acoustiques sous-marines

    OpenAIRE

    Goalic, André

    2006-01-01

    Les Sciences et Technologies de l'Information et de la Communication (STIC) continuent de progresser de façon spectaculaire dans tous les domaines de l'ingénierie ou de la production, des secteurs les plus traditionnels jusqu'aux industries de pointe. Les technologies mettant en oeuvre le traitement du signal et l'informatique permettant la mise au point de modèle de plus en plus réalistes, sont et seront à la base d'importantes innovations dans presque tous les secteurs de l'activité humaine...

  10. Traitement du signal et simulations pour l'élastographie ultrasonore impulsionnelle appliquée au foie

    OpenAIRE

    Stéphane, Audière

    2011-01-01

    L'évaluation de la fibrose hépatique est une source d'information essentielle pour le clinicien lors du diagnostic, traitement et suivi de maladies chroniques du foie. La société Echosens propose un appareil médical d'élastographie impulsionnelle ultrasonore, appelé Fibroscan. Cette technique consiste à mesurer la vitesse de propagation d'une onde de cisaillement dans le tissu hépatique engendrée par une sollicitation mécanique. La vitesse de cisaillement est directement reliée au degré de fi...

  11. Facteurs prédictifs de l’échec de traitement antituberculeux en Guinée Conakry

    Science.gov (United States)

    Nimagan, Souleymane; Bopaka, Regis Gothard; Diallo, Mamadou Mouctar; Diallo, Boubacar Djelo; Diallo, Mamadou Bailo; Sow, Oumou Younoussa

    2015-01-01

    La tuberculose est un véritable problème de santé publique. C'est une maladie guérissable et cette guérison passe par une bonne prise en charge thérapeutique. Il arrive parfois on assiste à l’échec thérapeutique, d'où l'intérêt de notre étude portant sur les facteurs prédictifs de ses échecs. Dans l'espace d'une année sur 1300 cas de tuberculose toute forme confondue, 700 cas de tuberculose pulmonaire à microscopie positive ont été répertorié dont 100 cas transférés. La tranche d’âge de 15-25 ans a été la plus touchée avec un sexe-ratio de 2 en faveur des hommes et 41,66% de nos malades ont été les ouvriers suivis de 20,83% des commerçants. La majorité de nos patients provenait de Conakry soit 99, 5%. Sur 600 patients suivis les nouveaux cas représentaient 83,33% et l’échec thérapeutique représentait 12 cas soit 2%. L'interruption du traitement représente le principal facteur de l’échec. Les facteurs qui ont influencé la régularité des malades au traitement ont été multiples. Des facteurs liés à l'organisation du système de santé, la rupture des médicaments antituberculeux, l’éducation sanitaire insuffisante, les contraintes de la supervision du traitement, l'implication insuffisante et la vente des médicaments par le personnel de santé. Des facteurs liés aux patients eux-mêmes, la crainte de perte d'emploi, les contraintes financières. Les renforcements de l'organisation du système sanitaire et l’éducation thérapeutiques pourront réduire le taux d’échec du traitement antituberculeux. L'amélioration de la qualité de la prise en charge des malades en situation d’échec devrait passer par une culture systématique des expectorations avec antibiogramme. PMID:26889327

  12. GOTHIC Simulation of APR1400 Auxiliary Charging Pump room heat up

    Energy Technology Data Exchange (ETDEWEB)

    Ha, Hui-Un; Heo, Sun [KHNP, Daejeon (Korea, Republic of)

    2014-10-15

    As a part of the Advanced Power Reactor 1400 (APR1400) U. S. Nuclear Regulatory Commission Design Certification (NRC DC) project, we have been investigating Auxiliary Charging Pump (ACP) room heat up. With reference to the design specification of the ACP room, we determined input information and developed a GOTHIC model of the APR1400 ACP room. This calculation model is described herein, and representative results from the calculation are presented as well. The results of the present paper are used to determine the integrity of ACP operating in the accident. APR 1400 GOTHIC model was developed for ACP room heat up calculation. Calculation results confirm that door opening is cooling the room properly. It is found that the difference due to the surface option of heat conductors is insignificant. Based on this result, further studies should be performed to confirm integrity of ACP.

  13. Evaluations physico-chimiques et biologiques de polyéthylène téréphthalate (PET) après traitement de surface par irradiations LASER en vue d'applications biomédicales

    OpenAIRE

    Mayer, Grégoire

    2007-01-01

    Les progrès remarquables réalisés dans le domaine des biomatériaux ont permis de proposer aux patients de remplacer certains organes déficients. Malheureusement, utilisés à l'état originel, certains matériaux ne répondent pas parfaitement aux exigences qui leurs sont imposées ; c'est le cas notamment des prothèses vasculaires en polyéthylène téréphthalate (PET) qui sont aujourd'hui couramment employées, mais qui peuvent encore être à l'origine de troubles importants pour le patient lorsqu'ell...

  14. Spontaneous radiopathological evolution and after medical treatment in two models of localized irradiation. Evolution radiopathologique spontanee et apres traitement medical dans deux modeles d'accident d'irradiation localisee

    Energy Technology Data Exchange (ETDEWEB)

    Lefaix, J.L.; Daburon, F.; Tricaud, Y. (CEA Centre d' Etudes de Fontenay-aux-Roses, 92 (France). Dept. de Pathologie Experimentale)

    1992-09-01

    Pathophysiological evolution of a [sup 192]Ir [gamma]-rays radio-induced muscular lesion was studied in experimental models developed in pigs and rabbits to simulate accidents which occurred among humans. Cutaneous and muscular radionecrosts started from early epithelial, microvascular and vascular lesions and late muscular and connective tissue lesions. Our therapeutic studies in pigs showed the interest of an early surgical treatment a minima. In rabbits, the association of non-steroidal anti-inflammatory (flurbiprofene) and haemorrheological agent (trimetazidine) among 10 other medical treatments, given for 8 weeks after an irradiation of a 80 Gy dose at the skin surface, involved a dose reduction factor of 2, with regards to the evolution of the skin injuries and the deep muscular fibronecrotic process. Tabs.

  15. Radio-induced glioblastoma and myxoma after treatment of undifferentiated carcinoma of the nasopharynx; Glioblastome et myxome radio-induits apres traitement d'un carcinome indiffencie du nasopharynx

    Energy Technology Data Exchange (ETDEWEB)

    Daoud, J.; Ben Salah, H. [Centre Hospitalier Universitaire Habib-Bourguiba, Service de Carcinologie-Radiotherapie, Sfax (Tunisia); Kammoun, W.; Ghorbel, A.; Drira, M.M. [Centre Hospitalier Universitaire Habib-Bourguiba, Service ORL, Sfax (Tunisia); Frikha, M. [Centre Hospitalier Universitaire Habib-Bourguiba, Service de Carcinologie Medicale, Sfax (Tunisia); Jlidi, R. [Centre Hospitalier Universitaire Habib-Bourguiba, Lab. d' Anatomo-Pathologie, Sfax (Tunisia); Besbes, M.; Maalej, M. [Institut Salah-Azaiz, Service de Carcinologie-Radiotherapie, Tunis (Tunisia)

    2000-12-01

    Radio-induced tumor have been known for a long time to occur after treatment of cancer during childhood. This entity is exceptional following radiotherapy of the cavum. Skull and facial osteosarcoma were described after treatment of UCNT. We report two observations of radio-induced tumors arising respectively three and seven years after treatment of UCNT. The first one is a temporo-parietal glioblastoma and the second is a rhino- and pharyngeal myxoma. The two patients are alive after treatment of the second tumor. The delay of appearance of these tumors, their situation in the field's irradiated and dose received suggests their radioinduced nature. However, the cytogenetic study is necessary to confirm the implication of radiotherapy in the genesis of these cancers. (authors)

  16. Les tableaux de fréquences 2 x 2 et leur traitement statistique

    Directory of Open Access Journals (Sweden)

    Louis Laurencelle

    2007-03-01

    Full Text Available Fait peu connu des chercheurs, voire des statisticiens appliqués, les tableaux de fréquences 2 × 2 appartiennent à trois catégories logiques différentes, selon que les effectifs totaux des rangées et des colonnes soient fixés d’avance ou non. Dans le modèle sans prédétermination, ou modèle 0, chaque élément peut s’inscrire dans n’importe quelle rangée ou colonne, comme lorsqu’on croise deux items dichotomiques d’un questionnaire. N’ayant trouvé aucun traitement spécifique de ce modèle dans la documentation, nous en proposons un, l’indice de concordance C, vérifié statistiquement par un simple test binomial. La comparaison des proportions obtenues dans deux groupes représente le modèle 1, les tailles de groupes étant prédéterminées : un test dû à Liddell et son approximation par le Khi-deux sont proposés, justifiés et validés. Enfin, dans le modèle 2, le total des réponses d’une sorte et de l’autre est connu d’avance ; pour ces cas, plus rares, le « test exact de Fisher » sied parfaitement, et le Khi-deux de Yates (avec correction de - 1/2 n en est l’approximation par excellence. Les tests basés sur les rapports de vraisemblance ainsi que d’autres approximations sont aussi discutés.

  17. Première expérience de l'utilisation du Misoprostol comme soin après avortement (SAA) à Libreville, Gabon

    Science.gov (United States)

    Mayi-Tsonga, Sosthène; Minkobame, Ulysse; Mbila, Arielle; Assoumou, Pamphile; Diop, Ayisha; Winikoff, Beverly

    2014-01-01

    Introduction Une étude a été menée afin de déterminer le taux d'acceptabilité de 400µg de misoprostol par voie sublinguale comme traitement de première intention de l'avortement incomplet et de préciser le taux d'avortement complet ou vacuité utérine. Méthodes Les femmes éligibles avaient un diagnostic clinique d'avortement incomplet avec une taille utérine inférieure à celle d'un utérus de 12 semaines d'aménorrhées (SA). Chacune a reçu 400µg de misoprostol par voie sublinguale. Les femmes ont été revues après une semaine. A J7, celles qui n'avaient pas complètement expulsé ont eu le choix entre une nouvelle consultation de suivi à J14 et la pratique d'une évacuation chirurgicale immédiate. Résultats 145 patientes ont été éligibles et ont toutes accepté la méthode (100%). L’âge moyen était de 25,9 ± 6 ans. A J7, 120 patientes étaient guéries (85,7%). A J14, le taux de réussitea été de 95,7% soit 134 patientes guéries. Les patientes guéries ont déclaré être très satisfaites (57,5%), satisfaites (41,8%) et insatisfaite (0,7%). Au total,128 femmes (95,5%) ont dit être prêtes à utiliser de nouveau le misoprostol comme méthode d’évacuation utérine en cas d'avortement incomplet. Conclusion L’étude démontre que le 400µg misoprostol par voie sublinguale nous permet de prendre en charge d'une manière adéquate l'avortement incomplet surtout dans les pays à faible ressource et notamment dans les structures sanitaires de première ligne ou éloignées. PMID:25469194

  18. Evaluation of ex-vessel steam explosion load for APR1400 using IFCI

    International Nuclear Information System (INIS)

    The load of ex-vessel steam explosion for APR1400 is evaluated using the IFCI 6.0 code developed by US NRC. The IFCI code is applied to analyse the FCI experiments of FARO-28, KROTOS-44 and TROI-13 as a code V/V process. The load of ex-vessel steam explosion for APR1400 is calculated based on the conditions applied during the code V/V and the load was compared with the analysis result of licence. The IFCI analysis result shows that the integrity of cavity might not be guaranteed once a steam explosion occurs and the result is in contrast with that of licence

  19. Spectral Matrix Filtering Applied to Vsp Processing Application du filtrage matriciel au traitement des profils sismiques verticaux

    Directory of Open Access Journals (Sweden)

    Glangeaud F.

    2006-11-01

    ère peut être extraite après horizontalisation et application d'un filtrage matriciel avec une forte moyenne en fréquence. Ce traitement est alors équivalent à un filtrage en vitesse apparente classique. Le filtrage matriciel peut conduire à une séparation d'onde sans connaissance a priori sur la vitesse apparente des différentes ondes. Dans le domaine fréquentiel, une onde W(f peut s'écrire comme le produit d'une ondelette A(f par un vecteur normalisé S(f caractérisant la surface d'onde. Pour un modèle à deux ondes W1(f = A1(f S1(f et W2(f = A2(f S2(f, quatre cas sont possibles : a Si les amplitudes des deux ondes W1 et W2 sont identiques à toutes les fréquences et si les ondes sont orthogonales ( = 0, représente le produit scalaire; les deux ondes sont projetées sur les 2 premiers vecteurs de façon équipotente et la séparation est impossible. b Si les amplitudes des deux ondes W1 et W2 sont identiques à toutes les fréquences et si les ondes ont des vitesses apparentes très proches ( ~ 1; les deux ondes sont projetées sur le premier vecteur propre et la séparation est impossible. c Si les amplitudes des ondes W1 et W2 sont différentes à toutes les fréquences et si les ondes sont orthogonales ( = 0, la séparation est parfaitement bien réalisée, chaque onde se projetant sur un vecteur propre. d Si les ondes ont des amplitudes très différentes et des vitesses apparentes très proches ( ~1, la séparation est partiellement réalisée. L'onde de plus forte amplitude est projetée sur le premier vecteur propre. L'onde de plus faible amplitude est projetée partiellement sur le deuxième vecteur propre. Les amplitudes relatives de chaque onde ne sont pas conservées. Les cas (c et (d sont illustrés par des exemples synthétiques présentés en figures 3 et 4. L'application de la technique de filtrage matriciel est illustrée à l'aide de deux exemples. Le premier exemple montre des données sismiques obtenues dans un puits vertical avec un g

  20. Introduction au traitement mathématique des images méthodes déterministes

    CERN Document Server

    Bergounioux, Maïtine

    2015-01-01

    Ce cours est une introduction au traitement d'image mathématique déterministe. Les principales problématiques en traitement et analyse d’image y sont présentées: débruitage/filtrage/restauration, segmentation, rehaussement/défloutage, ainsi qu’un aperçu de quelques techniques d’acquisition. Les méthodes mathématiques utilisées ont essentiellement déterministes : transformation de Fourier, ondelettes, équations aux dérivées partielles, morphologie mathématique et méthodes variationnelles. Quelques applications y sont brièvement présentées pour illustrer le propos : la stéganographie, la compression et l’inpainting (ou désocclusion). Le livre comprend également un rappel des principales notions mathématiques utilisées (il se veut auto-suffisant) et la bibliographie abondante doit permettre au lecteur d’approfondir les techniques qui l’intéressent. Cet ouvrage s’adresse à des étudiants de MASTER, élèves-ingénieurs ou chercheurs désireux de comprendre ou d’approfond...

  1. The Alberta Pregnancy Outcomes and Nutrition (APrON) cohort study : rationale and methods

    NARCIS (Netherlands)

    Kaplan, Bonnie J.; Giesbrecht, Gerald F.; Leung, Brenda M. Y.; Field, Catherine J.; Dewey, Deborah; Bell, Rhonda C.; Manca, Donna P.; O'Beirne, Maeve; Johnston, David W.; Pop, Victor J.; Singhal, Nalini; Gagnon, Lisa; Bernier, Francois P.; Eliasziw, Misha; McCargar, Linda J.; Kooistra, Libbe; Farmer, Anna; Cantell, Marja; Goonewardene, Laki; Casey, Linda M.; Letourneau, Nicole; Martin, Jonathan W.

    2014-01-01

    The Alberta Pregnancy Outcomes and Nutrition (APrON) study is an ongoing prospective cohort study that recruits pregnant women early in pregnancy and, as of 2012, is following up their infants to 3 years of age. It has currently enrolled approximately 5000 Canadians (2000 pregnant women, their offsp

  2. Assessment of Capability of MARS Code for Safety Evaluation of APR+ PAFS

    International Nuclear Information System (INIS)

    In South Korea, advanced power reactor plus (APR+), as a Korean specific reactor, is currently under development for the export strategy. In order to raise competitiveness of the APR+ in the world market, it is necessary to develop the original technology for the improved technology, economics, and safety features. For this purpose, a passive auxiliary feedwater system (PAFS) was adopted as an improved safety design concept of APR+: and then there have been many efforts to develop the PAFS. According to PAFS design concept, PAFS can completely replace the auxiliary feedwater system. When the design basis accident, in which feedwater is not available, occurs, the PAFS can remove the residual heat in the core and then prevent the core damage. In order to develop the safety evaluation system for APR+ PAFS, it is required to assess the calculation capability of MARS code for the passive system with the horizontal type heat exchanger. For this purpose, the main contents of this study are: 1) to simulate the TH phenomena such as natural circulation and horizontal condensation heat transfer in NOKO experiment using MARS-KS, 2) to compare the simulation results between RELAP5 and MARS for PAFS input model

  3. CFD Simulation of Acoustic-Induced Vibration in Main Steam Line of APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Lim, Sang Gyu; Kim, Tae Jun; Kim, Han Gon [Korea Hydro and Nuclear Power, Daejeon (Korea, Republic of)

    2012-05-15

    In recently, many boiling water reactors (BWRs) implement extended power uprate (EPU) to increase economic benefits. After EPU, Quad Cities power plant has been experienced damage of steam dryers due to acoustic-induced vibration. Acoustic resonance is produced by the interaction between the sound field and an unstable shear layer when the dry steam flows across the closed branch pipes such as safety relief valve(SRV). The unsteady vortices are separated at the leading edge of branch pipe and generated fluctuating pressure wave. After this experience, US-NRC issued that the licensee for new type of reactor should perform a vibration assessment program for an adverse flow effect in the main steam line in accordance with regulatory guideline 1.20 revision 3. In Korea, KHNP CRI implements comprehensive vibration program for steam generator of APR1400 and evaluates acoustic-induced vibration in main steam line using a commercial CFD code, ANSYS CFX 13.0. This paper deals with benchmark analysis to obtain applicability and reliability of commercial code for prediction of acoustic resonance phenomenon in case of single branch pipe test. Based on the benchmark analysis, analysis of main steam line in APR1400 plant is performed. In case of APR1400, five main steam safety valves are installed in the main steam line. Finally, this paper shows a prediction result of acoustic induced vibration characteristic in main steam system of APR1400

  4. An integral effect test on the feedwater line break of APR1400 with the ATLAS facility

    International Nuclear Information System (INIS)

    An integral effect test on the feedwater line break (FLB) was performed with the ATLAS facility for an APR1400 as a typical secondary system transient. The objectives of the present FLB tests are to understand the accident progression of the FLB scenario based on the APR1400 preliminary safety analysis report (PSAR) and to assess the prediction capability of system analysis codes such as the MARS, RELAP5, TRACE and SPACE. The main concern of the present FLB test is the peak RCS pressure and the major parameters affecting the peak RCS pressure are the break size, the break location, potential for reverse flow, initial pressurizer level and the initial SG level. The present test is performed for a break on the pipe connected to the economizer with a typical break size. The initial steady-state conditions and the sequence of event of FLB scenario for the APR1400 were successfully simulated with the ATLAS facility. In the present paper, major thermal-hydraulic phenomena such as the system pressures, the collapsed water levels, and the break flow rate are presented and discussed. It could be concluded that the APR1400 has the capability of coping with the hypothetical FLB scenario with an adequate set of controlling devices and proper setpoints. This integral effect test data could also be used to evaluate the prediction capability of existing safety analysis codes of MARS, RELAP5 and SPACE and to identify any code deficiency for an FLB simulation. (author)

  5. Assessment of Capability of MARS Code for Safety Evaluation of APR+ PAFS

    Energy Technology Data Exchange (ETDEWEB)

    Jeon, Seong Su; Lee, Byung Chul [Seoul National University, Seoul (Korea, Republic of); Park, Ju Yeop; Seul, Kwang Won [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2011-05-15

    In South Korea, advanced power reactor plus (APR+), as a Korean specific reactor, is currently under development for the export strategy. In order to raise competitiveness of the APR+ in the world market, it is necessary to develop the original technology for the improved technology, economics, and safety features. For this purpose, a passive auxiliary feedwater system (PAFS) was adopted as an improved safety design concept of APR+: and then there have been many efforts to develop the PAFS. According to PAFS design concept, PAFS can completely replace the auxiliary feedwater system. When the design basis accident, in which feedwater is not available, occurs, the PAFS can remove the residual heat in the core and then prevent the core damage. In order to develop the safety evaluation system for APR+ PAFS, it is required to assess the calculation capability of MARS code for the passive system with the horizontal type heat exchanger. For this purpose, the main contents of this study are: 1) to simulate the TH phenomena such as natural circulation and horizontal condensation heat transfer in NOKO experiment using MARS-KS, 2) to compare the simulation results between RELAP5 and MARS for PAFS input model

  6. Greta Kaits 9. apr. 1928 - 29. aug. 1946 : [luuletused] / Mats Traat

    Index Scriptorium Estoniae

    Traat, Mats, 1936-

    2008-01-01

    Sisu : Greta Kaits 9. apr. 1928 - 29. aug. 1946 ; Villem Hänilane 1898 - 1952 ; Peeter Pedak 1897 - 1953 ; Max Äidse 1903 - 1959 ; Lavinia Laidam ; Buchard Pruus ; Sergei Krivokopõtov ; Allan Luht 5. VII 1962 - 17. V 2007 ; Karl Saarmets 9. III 1924 - 14. IX 1981 ; Raimo Ritsik

  7. Traitement par plasma thermique d'une liqueur caustique pour la destruction des cyanures

    Science.gov (United States)

    Fortin, Luc

    L'objectif principal de cette recherche est d'evaluer la possibilite de traiter le lixiviat de brasques usees produit par le procede LCL&L (Lixiviation a bas caustique et chaulage) par contact direct avec un jet de plasma thermique. L'utilisation d'un chalumeau au plasma permet d'eliminer les problemes de reaction avec les produits de combustion relies a l'utilisation de chalumeaux conventionnels (e.g. carbonatation du NaOH en Na2CO3). Le fait de se servir de ce type de chalumeau en mode submerge pour le traitement d'une solution liquide constitue l'originalite du projet. Les essais effectues dans le cadre de ce travail experimental sont realises a l'echelle banc d'essai dans un premier temps. Ils visent a determiner le taux de decomposition des cyanures contenus dans le lixiviat sous des conditions de plasma thermique en fonction de differents parametres et a faire la mise a l'echelle d'un reacteur pilote. La puissance electrique fournie au chalumeau, la temperature et la pression d'operation, le point d'addition d'eau, le volume de lixiviat traite et l'addition de peroxyde d'hydrogene (H2O2) comme co-reactif ont tous un impact sur le taux de destruction des cyanures trouve. Sous toutes les conditions etudiees, le reacteur plasma offre un taux de destruction plus rapide qu'un reacteur agite sous pression pour une meme concentration en cyanures. Ainsi, la comparaison de la constante cinetique obtenue pour le reacteur agite avec une constante similaire pour le reacteur plasma (pente du graphique -ln(C/C0) en fonction du temps) est de 0.04x10-3 s-1 vs 0.59x10-3 s-1 a 100°C et de 1.85x10-3 s-1' vs 3x10 -3 s-1s a 170°C. Ces resultats confirment que le plasma joue un role important sur la decomposition des cyanures et qu'il contribue a en augmenter le taux de destruction. Suite aux connaissances acquises sur le banc d'essai, un reacteur pilote est concu. Un chalumeau au plasma d'une puissance de 60 kW-150 kW et fonctionnant avec l'air comme gaz plasmagene y est

  8. Traitement d'éffluents gazeux malodorants issus du secteur industriel du traitement des déchets par voie biologique : étude du couplage lit percolateur/biofiltre

    OpenAIRE

    Soupramanien, Alexandre

    2012-01-01

    Le secteur industriel du traitement des déchets génère des émissions gazeuses induisant des nuisances odorantes auprès des populations riveraines des installations. Ces effluents gazeux contiennent une grande diversité de composés volatils : oxygénés (acides gras volatils, cétones, aldéhydes, alcools), azotés et soufrés (hydrogène sulfuré (H2S), diméthylsulfure (DMS), diméthyldisulfure (DMDS) et méthanethiol (MT)). Ces effluents gazeux sont traités par un dispositif approprié que sont les bio...

  9. Modèles bayésiens hiérarchiques pour le traitement multi-capteur

    OpenAIRE

    Dobigeon, Nicolas

    2007-01-01

    Afin de traiter la masse d'informations récoltée dans de nombreuses applications, il est nécessaire de proposer de nouvelles méthodes de traitement permettant d'exploiter le caractère « multi-capteur » des données observées. Le sujet de cette thèse consiste à étudier des algorithmes d'estimation dans un contexte multi-capteur où plusieurs signaux ou images issus d'une même application sont disponibles. Ce problème présente un grand intérêt puisqu'il permet d'améliorer les performances d'estim...

  10. Etude morphologique et métrologique des sinus de Valsalva par traitement d'images tomographiques

    OpenAIRE

    Blanchard, Cédric

    2012-01-01

    L'objectif de cette thèse est l'élaboration et l'application de traitements d'images pour permettre une étude objective et fiable des sinus de Valsalva, importantes cavités de la base de l'aorte. Les méthodes proposées s'appliquent aux séquences ciné-IRM et aux examens de scanner sans qu'il n'y ait à modifier le paramétrage entre deux examens. Pour cela, nous avons d'abord étudié la morphologie de cette zone anatomique puis détaillé les différentes propriétés communes à toutes les images de s...

  11. Phimosis et corticostéroïdes topiques : une alternative au traitement chirurgical? : revue Cochrane pour le praticien

    OpenAIRE

    Flatz A.; Rey-Bellet Gasser C.; Peytremann-Bridevaux I.

    2015-01-01

    Question clinique: Une mère vous consulte avec son fils âgé de 6 ans, en bonne santé habituelle mais connu pour un phimosis. Il ne présente pas de troubles mictionnels, ni d'antécédents de balanite ou de paraphimosis. Sa mère est inquiète de voir le phimosis persister et vous demande s'il existe une alternative au traitement chirurgical. Contexte: Présent dès la naissance, le phimosis physiologique se résout spontanément dans la majorité des cas. Alors que 10% des garçons présentent un phimos...

  12. Les Determinants du Desir De Grossesse chez les Femmes Seropositives sous Traitement AntiRetroviral dans le District de Rwamagana

    OpenAIRE

    Claudien Uwanyirigira; Cyprien Munyanshongore

    2013-01-01

    L’étude vise à analyser les déterminants du désir de grossesse chez les femmes séropositives sous traitement anti-retroviral, afin de contribuer à la réduction de la transmission du virus de la mère à l’enfant. Elle a pour objectifs spécifiques de déterminer la proportion des grossesses chez les femmes à sérologie VIH positive, d’évaluer l’attitude du personnel de santé à l’égard des messages à donner aux femmes séropositives sous ARVs en ce qui concerne le désir de la grossesse, et relever l...

  13. Minimisation de la pollution générée par un atelier de traitement de surface

    OpenAIRE

    Leveillard, Florine; Laforest, Valérie; Bourgois, Jacques

    2012-01-01

    Le traitement de surface est une activité industrielle générant un chiffre d'affaire annuel de 6 milliards d'euros en France, 900 000 tonnes de matériaux d'apport sont appliqués sur 3 milliards de mètres-carrés. Lorsque cette branche industrielle utilise la voie aqueuse, cette activité est grande consommatrice d'eau et de produits chimiques et donc génératrice de rejets aqueux pollués. L'objectif de ce travail est de proposer une méthodologie simple de limitation des flux de pollution ainsi q...

  14. Traitement des plantes textiles à Maurecourt « la Croix de Choisy » (Yvelines) au Néolithique ancien

    OpenAIRE

    Dietsch-Sellami, Marie-France; Durand, Stéphane; Verdin, Pascal

    2014-01-01

    Le site de « La Croix de Choisy » à Maurecourt (Yvelines) forme un ensemble cohérent attribuable à une phase récente du groupe Bliquy – Villeneuve-Saint-Germain. L’hypothèse d’un traitement de plantes textiles est émise pour quatre fosses « particulières » par leur morphologie et comblement. Des analyses de phytolithes et macrorestes végétaux ont été engagées et ont révélé la présence sur le site d’ortie (Urtica dioïca) et de lin (Linum usitatissimum), ce dernier jusque là inconnu au Néolithi...

  15. Activités du Cemagref en épuration des eaux et traitement des effluents d'élevage

    OpenAIRE

    Héduit, A.

    2010-01-01

    / Le Cemagref développe depuis les années 70 des travaux destinés à améliorer l'efficacité des stations d'épuration des eaux usées et des procédés de traitement des effluents d'élevage. L'ensemble de ces activités est mis en oeuvre dans le cadre de l'axe EPURE du thème de recherche Technologies et procédés pour l'Eau et les Déchets (Axe TED-E) qui regroupe une cinquantaine de personnes localisées à Antony, Bordeaux, Lyon et Rennes dont une vingtaine d'ingénieurs et de chercheurs travaillan...

  16. Le Rôle de l’Omalizumab dans le Traitement de l’Asthme Allergique Grave

    OpenAIRE

    Chapman, Kenneth R.; André Cartier; Jacques Hébert; R Andrew McIvor; R Robert Schellenberg

    2006-01-01

    CONTEXTE : Un nouveau traitement anti-immunoglobuline E (anti-IgE) contre l’asthme, l’omalizumab, a été approuvé au Canada.OBJECTIF : Passer en revue les données fondamentales et cliniques sur l’omalizumab et examiner le rôle possible de ce médicament dans la prise en charge de l’asthme au Canada.MÉTHODOLOGIE : Une recherche documentaire a été effectuée dans MEDLINE afin de repérer les études menées de 1960 à 2006 sur l’omalizumab. La recherche a également porté sur les résumés de réunions sc...

  17. Quel traitement lexicographique de l’onomastique commerciale ? Pour une distinction Nom de marque/Nom de produit

    OpenAIRE

    Fèvre-Pernet, Christine; Roché, Michel

    2014-01-01

    Le traitement lexicographique de ce que l’on appelle noms déposés, marques déposées ou « noms de marques » pose problème. Au sein de l’onomastique commerciale, les noms de marques et les noms de produits constituent, linguistiquement, deux classes distinctes : c’est ce que nous montrons dans cet article en nous appuyant sur différents critères. Ils se comportent différemment sur le plan pragmatique (identification de l’origine ou du contenu, réponse à un besoin de nomination), référentiel (na...

  18. La place du traitement dans la gestion des excédents structurels d'effluents d'élevage

    OpenAIRE

    Gitton, C.; Hurvois, Y.

    1999-01-01

    Le défi qui doit être relevé aujourd'hui est la restauration d'un lien entre le sol et les élevages hors-sol qui consomment massivement des aliments produits en dehors de l'exploitation. Il faut pour cela tenir compte de la capacité épuratoire des sols et des cultures. Les régions qui ont fortement développé les élevages hors-sol sont aujourd'hui en situation d'excédent structurel lié aux élevages. Le recours au traitement des effluents d'élevage doit souvent compléter d'autres mesures de rés...

  19. Calculation of fuel and moderator temperature coefficients in APR1400 nuclear reactor by MVP code

    International Nuclear Information System (INIS)

    In this project, these fuel and moderator temperature coefficients were calculated in APR1400 nuclear reactor by MVP code. APR1400 is an advanced water pressurized reactor, that was researched and developed by Korea Experts, its electric power is 1400 MW. The neutronics calculations of full core is very important to analysis and assess a reactor. Results of these calculation is input data for thermal-hydraulics calculations, such as fuel and moderator temperature coefficients. These factors describe the self-safety characteristics of nuclear reactor. After obtaining these reactivity parameters, they were used to re-run the thermal hydraulics calculations in LOCA and RIA accidents. These thermal-hydraulics results were used to analysis effects of reactor physics parameters to thermal hydraulics situation in nuclear reactors. (author)

  20. Analysis of Air Cooling Performance in the Coil Stack Assembly for APR+ CEDMs

    International Nuclear Information System (INIS)

    The control element drive mechanisms (CEDMs) are electromechanical devices for withdrawing, inserting, holding or tripping the control element assemblies (CEAs). The driving power for CEDMs is supplied by the coil stack assembly mounted on the motor housing assembly. The Coil Stack assembly is heated by the motor housing assembly contacted with reactor coolant as well as electric resistance of coil. The CEDMs are cooled by air ventilation. The cooling air around the CEDMs flows into the individual cooling shroud and extracts heat from the coil stacks while it passes between the shroud and coil housing. The cooling performance of the CEDMs is closely related to the geometry configuration of coil stack assembly. The expansion of air passage and additional cooling fins are considered to improve the cooling performance of APR+ CEDMs. In this study the optimal design conditions of APR+ CEDMs are investigated by flow analysis

  1. Available Driving Head Following a Loss-of-Coolant Accident in the APR1400 Design

    International Nuclear Information System (INIS)

    The objective of in-vessel downstream effect (IDE) evaluation is to demonstrate that there is reasonable assurance that sufficient long-term core cooling (LTCC) is achieved with debris and chemical products which are postulated to be transported to the reactor vessel. To maintain LTCC, it should be demonstrated that the available head to drive emergency core cooling (ECC) flow into the core is greater than the head loss across the core due to possible debris buildup. In this paper, the available driving heads following a loss-of-coolant accident (LOCA) in the APR1400 design were presented. The available driving heads of the APR1400 design were calculated in case of HL break, CL break, and CL break after HLSO operation at the recirculation start time (700 seconds after ECC start). The break size spectrum will be analyzed to calculate the available driving head when the loop seal reformation happens after a small break LOCA

  2. External Reactor Vessel Cooling Strategy Application for APR1400 Station Blackout Scenarios

    International Nuclear Information System (INIS)

    In Korea, all NPPs implemented post-Fukushima measures. In U. S., the approach is to expand B5b strategy to build up FLEX strategies utilizing portable equipment. With portable pumps and connections, one can mitigate and respond to wide range of accidents. In this study, we examined the feasibility of cavity flooding using portable pumps for ERVC and its effectiveness in responding to extended SBO scenarios. The external reactor vessel cooling (ERVC) is one of important severe accident management (SAM) strategies adopted for APR1400. ERVC strategy is to remove decay heat from molten corium in lower plenum by submerging the vessel with water. The strategy requires water injection into cavity and APR1400 uses shutdown cooling pumps for this purpose, requiring electricity. Recent Fukushima accident shows the importance of mitigation capability against extended SBO scenarios

  3. Preliminary System Response Analysis of Rod Ejection Accident for APR1000

    International Nuclear Information System (INIS)

    Korea Electric Power Co. (KEPCO) has designed the Advanced Power Reactor 1000 (APR1000) plants implementing the advanced safety features to Optimized Power Reactor 1000 (OPR1000) plants. Prior to developing the detail design, the preliminary design project has been launched since the end of 2009 as a feasibility study. In spite of some difference in safety- related design concepts of two plant types, they could be treated as the same plants considering the main features or systems. In this study, the rod ejection accident (REA) event was analyzed using Korea Non-LOCA Analysis Package (KNAP) hot spot model (HSM) for APR1000 to examine the feasibility of the design concepts and the results were compared with those values calculated by the Safety Analysis Report (SAR) conditions of typical OPR1000 plants. Through the study, it was concluded that the design concepts and the analysis package could be applicable on the view point of REA

  4. External Reactor Vessel Cooling Strategy Application for APR1400 Station Blackout Scenarios

    Energy Technology Data Exchange (ETDEWEB)

    Tran, Quang Diep Khanh; Oh, Seung Jong [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of); Ro, Seo Mi [KHNP Central Research Institute, Daejeon (Korea, Republic of)

    2013-10-15

    In Korea, all NPPs implemented post-Fukushima measures. In U. S., the approach is to expand B5b strategy to build up FLEX strategies utilizing portable equipment. With portable pumps and connections, one can mitigate and respond to wide range of accidents. In this study, we examined the feasibility of cavity flooding using portable pumps for ERVC and its effectiveness in responding to extended SBO scenarios. The external reactor vessel cooling (ERVC) is one of important severe accident management (SAM) strategies adopted for APR1400. ERVC strategy is to remove decay heat from molten corium in lower plenum by submerging the vessel with water. The strategy requires water injection into cavity and APR1400 uses shutdown cooling pumps for this purpose, requiring electricity. Recent Fukushima accident shows the importance of mitigation capability against extended SBO scenarios.

  5. CFD Analysis of Flow Characteristics in the PAFS PCCT for APR +

    International Nuclear Information System (INIS)

    The passive auxiliary feedwater system (PAFS) is one of the passive safety features adopted in the APR+. The PAFS has two independent high-pressure closed loops; each loop has a heat exchanger (U-tube bundles) submerged in a PCCT water pool. The PAFS cools the secondary system by heat transfer in a horizontal Utube in the PCCT. The cooling water in the PCCT is maintained at atmospheric pressure, so that boiling heat transfers at the surface of the U-tube and natural convection occurs in the PCCT water pool. The conventional system codes, such as the RELAP5 /Mod3.3 and the MARS codes, are inadequate for flow pattern analysis of this system. The purpose of this study is to analyze the flow characteristics in the PAFS PCCT for APR + utilizing a CFD code, CFX

  6. CFD Analysis of Flow Characteristics in the PAFS PCCT for APR +

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Mun Soo; Chun, Jong [KHNP, Daejeon (Korea, Republic of)

    2010-10-15

    The passive auxiliary feedwater system (PAFS) is one of the passive safety features adopted in the APR+. The PAFS has two independent high-pressure closed loops; each loop has a heat exchanger (U-tube bundles) submerged in a PCCT water pool. The PAFS cools the secondary system by heat transfer in a horizontal Utube in the PCCT. The cooling water in the PCCT is maintained at atmospheric pressure, so that boiling heat transfers at the surface of the U-tube and natural convection occurs in the PCCT water pool. The conventional system codes, such as the RELAP5 /Mod3.3 and the MARS codes, are inadequate for flow pattern analysis of this system. The purpose of this study is to analyze the flow characteristics in the PAFS PCCT for APR + utilizing a CFD code, CFX

  7. The Gravity Makeup on the LORHR Event during Mid-loop Operation for APR1400

    International Nuclear Information System (INIS)

    This paper is to investigate means of the available gravity makeup after the event to prevent or sustain the core uncovery and fuel failure for the typical advanced power reactor nuclear power plants (APR1400). Unlike the OPR1000 (optimized power reactor 1000 nuclear power plants), the refueling water storage tank of APR1400 cannot be used for gravity makeup since it is located on the bottom of the containment with a lower elevation than the reactor vessel. So, the other means of gravity makeup and their effect on the core uncovery are accounted. The use of the water used for the cask loading pit (CLP) during refueling or the safety injection line filling tank (SIFT), which are not designed for gravity makeup during the event, and safety injection tanks (SITs) are considered as the alternative source of makeup feed. The results show that gravity makeup of a SIT provides a sufficient operator action time for the LORHR with the station black out (SBO) during the mid-loop operation for the APR1400. From the LORHR event analysis, the effective means of gravity makeup for APR1400 to cope with this event concurrent loss of all AC power is determined as the gravity feed using SITs. Other means for gravity makeup using CLP or SIFT, which are not designed to mitigate the LORHR event, are evaluated as not effective to the event due to the large flow resistances and the low elevation head to overcome the system pressure increase during the LORHR. The use of one SIT and two SITs for the LORHR provides the core uncovery times as 3 hr 8 min and 4 hr 32 min extending 1 hr 15 min and 2 hr 38 min from the base case, respectively

  8. Acute exercise does not induce an acute phase response (APR) in Standardbred trotters

    OpenAIRE

    Kristensen, Lena; Buhl, Rikke; Nostell, Katarina; Bak, Lars; Petersen, Ellen; Lindholm, Maria; Jacobsen, Stine

    2014-01-01

    The purpose of the study was to investigate whether acute strenuous exercise (1600- to 2500-m race) would elicit an acute phase response (APR) in Standardbred trotters. Blood levels of several inflammatory markers [serum amyloid A (SAA), haptoglobin, fibrinogen, white blood cell count (WBC), and iron], muscle enzymes [creatinine kinase (CK) and aspartate transaminase (AST)], and hemoglobin were assessed in 58 Standardbred trotters before and after racing. Hemoglobin levels increased and iron ...

  9. APR-5000-XLS阵列封装返工系统

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    APR-5000-XLS阵列封装返工系统可处理BGA,CSP,LGA(Land Grid Army),Micro SMD,MLF(Micro Lead Frame),BCC(Bumped Chip Component)多种封装。其可处理的板尺寸达610mm×610mm(24.5”×24.5”),厚度达6.35mm(0.25”)。

  10. Critical heat flux for APR1400 lower head vessel during a severe accident

    International Nuclear Information System (INIS)

    Highlights: ► Studied boiling on downward-facing hemispherical vessel with asymmetric thermal insulator. ► Scaled the APR1400 lower head linearly down by 1/10 including ICI tubes and shear keys. ► Performed thermal analysis using ANSYS V11.0 to determine the internal temperature and heat flux. ► Performed tests to obtain the CHF with saturated demineralized water at atmospheric pressure. ► Measured CHF accounting for 3D random flow effect expected in the APR1400 application. -- Abstract: Corium Ablation Stopper Apparatus (CASA) has a downward-facing hemispherical vessel and geometrically asymmetric thermal insulator of the Advanced Power Reactor 1400 MWe (APR1400) scaled linearly down by 1/10, as well as sixty-one in-core instrumentation (ICI) tubes and four shear keys. The heated vessel plays a pivotal role in CASA depending on the configuration of the oxide pool and metal layer to bring about the focusing effect expected of a molten pool in the lower head during a severe accident. The heated vessel was designed through a trial-and-error method and thermal analysis. Thermal analysis was performed using ANSYS V11.0 to investigate the effect of the internal temperature and heat flux on the integral hemispherical copper vessel. The CASA tests were carried out to obtain the critical heat flux (CHF) with saturated and demineralized water at the atmospheric pressure (0.1 MPa). The CHF in the metal layer through the hemispherical channel was found to be lower than that in the ULPU-2400 configuration V data through the streamlined thermal insulator. The experimental CHF was measured and obtained through the CASA hemispherical heated surface accounting for the three-dimensional random flow effect expected in the APR1400 application

  11. The Gravity Makeup on the LORHR Event during Mid-loop Operation for APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Cheol Woo; Lee, Yong Hee; Lee, Gyu Cheon; Kim, Shin Whan [KEPCO, Daejeon (Korea, Republic of)

    2015-05-15

    This paper is to investigate means of the available gravity makeup after the event to prevent or sustain the core uncovery and fuel failure for the typical advanced power reactor nuclear power plants (APR1400). Unlike the OPR1000 (optimized power reactor 1000 nuclear power plants), the refueling water storage tank of APR1400 cannot be used for gravity makeup since it is located on the bottom of the containment with a lower elevation than the reactor vessel. So, the other means of gravity makeup and their effect on the core uncovery are accounted. The use of the water used for the cask loading pit (CLP) during refueling or the safety injection line filling tank (SIFT), which are not designed for gravity makeup during the event, and safety injection tanks (SITs) are considered as the alternative source of makeup feed. The results show that gravity makeup of a SIT provides a sufficient operator action time for the LORHR with the station black out (SBO) during the mid-loop operation for the APR1400. From the LORHR event analysis, the effective means of gravity makeup for APR1400 to cope with this event concurrent loss of all AC power is determined as the gravity feed using SITs. Other means for gravity makeup using CLP or SIFT, which are not designed to mitigate the LORHR event, are evaluated as not effective to the event due to the large flow resistances and the low elevation head to overcome the system pressure increase during the LORHR. The use of one SIT and two SITs for the LORHR provides the core uncovery times as 3 hr 8 min and 4 hr 32 min extending 1 hr 15 min and 2 hr 38 min from the base case, respectively.

  12. An Experimental Investigation on APR1400 Penetration Weld Failure by Metallic Melt

    International Nuclear Information System (INIS)

    The penetrations are considered as the most vulnerable parts with respect to the reactor vessel failure when a core melt severe accident occurs and the corium reaches the lower head. Penetration tube failure modes can be divided into two categories; tube ejection out of the vessel lower head and rupture of the penetration tube outside the vessel. Tube ejection begins with degrading the penetration tube weld strength to zero as the weld is exposed to temperatures as high as the weld melting temperature, which is called weld failure, and then overcoming any binding force in the hole in the vessel wall that results from differential thermal expansion of the tube and vessel wall. Tube rupture assumes that the debris bed has melted the instrument tube inside the reactor and melt migrates down into the tube to a location outside the vessel wall where a pressure rupture can occur, thus breaching the pressure boundary. In the present paper, we have a focus on the tube ejection failure mode, specifically on the APR1400 weld failure by direct contact with a metallic melt. The objective is to investigate experimentally the ablation kinetics of an APR1400 penetration weld during the interactions with a metallic melt and to suggest the modification of the existing weld failure model. This paper involves the interaction experiments of two different metallic melts (metallic corium and stainless steel melts) with a weld specimen, and rough estimation of weld failure time. The interaction experiments between the metallic melts and an APR1400 penetration weld were performed to investigate the ablation kinetics of the penetration weld. Metallic corium and stainless steel melts were generated using an induction heating technique and interacted with a penetration weld specimen. The ablation rate of the weld specimen showed a range from 0.109 to 0..244 mm/s and thus the APR1400 penetration weld was estimated to be failed at hundreds of times after the interaction with the melt

  13. Development of the Diverse Means for Reactor Shutdown Function of EU-APR1400

    International Nuclear Information System (INIS)

    This paper provides general descriptions of the EBS focusing on basic design characteristics such as system function, configuration and operation, and presents results from the preliminary verification of system performance. The diverse means for the reactor shutdown function of EU-APR1400 have been developed to comply with the diversity principle of the European design requirements of a new nuclear power plant. The preliminary verification of the EBS performance was done by the ATWS analysis. The analysis results show that the EBS was designed properly. Diversity is the fundamental principle in safety system design of a new nuclear power plant, which uses different mitigation measures to provide diverse ways of responding to a significant event. Regarding the diversity principle, EU-APR1400 (European APR1400) safety system should be in accordance with European design requirements. EBS (Emergency Boration System) is designed to provide the diverse means to shut down the reactor against ATWS (Anticipated Transient Without Scram) and to mitigate the event consequences in the EUAPR1400

  14. Assistant Personal Robot (APR): Conception and Application of a Tele-Operated Assisted Living Robot

    Science.gov (United States)

    Clotet, Eduard; Martínez, Dani; Moreno, Javier; Tresanchez, Marcel; Palacín, Jordi

    2016-01-01

    This paper presents the technical description, mechanical design, electronic components, software implementation and possible applications of a tele-operated mobile robot designed as an assisted living tool. This robotic concept has been named Assistant Personal Robot (or APR for short) and has been designed as a remotely telecontrolled robotic platform built to provide social and assistive services to elderly people and those with impaired mobility. The APR features a fast high-mobility motion system adapted for tele-operation in plain indoor areas, which incorporates a high-priority collision avoidance procedure. This paper presents the mechanical architecture, electrical fundaments and software implementation required in order to develop the main functionalities of an assistive robot. The APR uses a tablet in order to implement the basic peer-to-peer videoconference and tele-operation control combined with a tactile graphic user interface. The paper also presents the development of some applications proposed in the framework of an assisted living robot. PMID:27136552

  15. Single-tube condensation experiment in Passive Auxiliary Feedwater System of APR1400+

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Chang Wook; No, Hee Cheon; Yun, Bong Yo; Jeon, Byong Guk [Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of)

    2012-05-15

    Conventional Korean nuclear power plants, Advanced Power Reactors (APR), are characterized by an active cooling system. However, Active cooling system may not prevent significant damage without any AC power source available for its operation as vividly illustrated through the recent Fukushima incident. In the APR1400+ to be designed, an independent passive cooling system was added in order to overcome the aforementioned shortcomings. In the Passive Auxiliary Feedwater System (PAFS), gravity force and density difference between steam and water are used. The system comprises of 240 condensation tubes to efficiently remove decay heat. Before applying the PAFS to APR1400+, the system's safety and heat removal performance must be verified. The present study experimentally evaluates the heat removal performance of a single tube in the PAFS. The objectives of SCOP (Single-tube Condensation experiment facility of PAFS) are the evaluation of the heat removal performance in the tube of the PAFS and database construction under various tube designs and test conditions. Reaching these objectives, we developed advanced measurement techniques for the amount of moisture, heat flux, and water film thickness.

  16. Assistant Personal Robot (APR: Conception and Application of a Tele-Operated Assisted Living Robot

    Directory of Open Access Journals (Sweden)

    Eduard Clotet

    2016-04-01

    Full Text Available This paper presents the technical description, mechanical design, electronic components, software implementation and possible applications of a tele-operated mobile robot designed as an assisted living tool. This robotic concept has been named Assistant Personal Robot (or APR for short and has been designed as a remotely telecontrolled robotic platform built to provide social and assistive services to elderly people and those with impaired mobility. The APR features a fast high-mobility motion system adapted for tele-operation in plain indoor areas, which incorporates a high-priority collision avoidance procedure. This paper presents the mechanical architecture, electrical fundaments and software implementation required in order to develop the main functionalities of an assistive robot. The APR uses a tablet in order to implement the basic peer-to-peer videoconference and tele-operation control combined with a tactile graphic user interface. The paper also presents the development of some applications proposed in the framework of an assisted living robot.

  17. Assistant Personal Robot (APR): Conception and Application of a Tele-Operated Assisted Living Robot.

    Science.gov (United States)

    Clotet, Eduard; Martínez, Dani; Moreno, Javier; Tresanchez, Marcel; Palacín, Jordi

    2016-01-01

    This paper presents the technical description, mechanical design, electronic components, software implementation and possible applications of a tele-operated mobile robot designed as an assisted living tool. This robotic concept has been named Assistant Personal Robot (or APR for short) and has been designed as a remotely telecontrolled robotic platform built to provide social and assistive services to elderly people and those with impaired mobility. The APR features a fast high-mobility motion system adapted for tele-operation in plain indoor areas, which incorporates a high-priority collision avoidance procedure. This paper presents the mechanical architecture, electrical fundaments and software implementation required in order to develop the main functionalities of an assistive robot. The APR uses a tablet in order to implement the basic peer-to-peer videoconference and tele-operation control combined with a tactile graphic user interface. The paper also presents the development of some applications proposed in the framework of an assisted living robot. PMID:27136552

  18. A Study on the Application of the Display Sharing Function In the APR1400 MCR

    International Nuclear Information System (INIS)

    APR1400 digital Main Control Room (MCR) has been applied to Korean Nuclear Power Plants since Shin-Kori 3 and 4. APR1400 MCR has the advantages to reduce the physical and mental workload and to increase situation awareness through integrated information of Compact Operator Console, Computerized Procedure System (CPS) and Large Display Panel (LDP). But although digital MCR has many advantages, it has a weak point that operators cannot easily oversee other operator's operational behavior like soft control actions. This environment makes it difficult to perform concurrent and independent verification from the viewpoint of human error prevention. This paper presents the application method and design of display sharing function through combination using Large Display Panel (LDP) and Information Flat Panel Display (IFPD) of operator console for more reliable operation than before. Because display sharing function is applied within the Information Processing System (IPS), it is required to maintain the system requirement of the IPS such as the CPU and network load. For quality assurance, display sharing function will be developed in accordance with Human Factors Engineering program (NUREG-0711) and Software Program Manual (SPM). We expect that this technology strengthen the reliable operation of the APR1400

  19. Single-tube condensation experiment in Passive Auxiliary Feedwater System of APR1400+

    International Nuclear Information System (INIS)

    Conventional Korean nuclear power plants, Advanced Power Reactors (APR), are characterized by an active cooling system. However, Active cooling system may not prevent significant damage without any AC power source available for its operation as vividly illustrated through the recent Fukushima incident. In the APR1400+ to be designed, an independent passive cooling system was added in order to overcome the aforementioned shortcomings. In the Passive Auxiliary Feedwater System (PAFS), gravity force and density difference between steam and water are used. The system comprises of 240 condensation tubes to efficiently remove decay heat. Before applying the PAFS to APR1400+, the system's safety and heat removal performance must be verified. The present study experimentally evaluates the heat removal performance of a single tube in the PAFS. The objectives of SCOP (Single-tube Condensation experiment facility of PAFS) are the evaluation of the heat removal performance in the tube of the PAFS and database construction under various tube designs and test conditions. Reaching these objectives, we developed advanced measurement techniques for the amount of moisture, heat flux, and water film thickness.

  20. Consideration of MAAP 5.0.2 ESF Model Characteristics for APR1400 NPP

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Mi Ro; Kim, Hyeong Taek [KHNP-CRI, Daejeon (Korea, Republic of)

    2014-10-15

    After the Fukushima accident, EPRI has developed the MAAP (Modular Accident Analysis Program) version 5 that is expected to make up the limitation of MAAP4, that is to say, the appropriateness of the model for the severe accident phenomena and the applicability to the phenomena in the spent fuel pool and the halfloop operation. Up to now, the newest version of MAAP is 5.0.2 (Build 5020000) that was released officially in December, 2013. In addition to this, it is expected that MAAP 5.0.3 version will be published sooner or later. As a kind of post-Fukushima measures, KHNP is developing the probabilistic safety assessment (PSA) and severe accident management guideline (SAMG) for low power and shutdown (LPSD) mode and MAAP 5.0.2 should be used in these projects as a major analysis program. So, first of all, it is necessary that the parameter file for domestic NPP should be upgraded as current Ver. MAAP4 to Ver. MAAP 5.0.2. KHNP has developed the draft version of parameter file for APR1400 type NPP and is being upgraded continuously. The Engineering Safety Features (ESF) model is one of the unique features of MAAP. In this study, we try to share the general information of the MAAP ESF model and the specific characteristics of APR1400 ESF model based on the newly developed MAAP 5.0.2 parameter file. Currently, while developing the LPSD PSA and LPSD SAMG as a kind of post-Fukushima measures, KHNP have the plan in order to upgrade the old parameter file based on MAAP4 to that based on MAAP5.0.2 for all domestic nuclear power plants. And, as the first effort, we are developing the MAAP 5.0.2 parameter file for APR1400 type NPP. In this study, we tried to develop the more accurate and reasonable ESF model of APR1400. In this process, we can find the distinctions and characteristics of specific ESF model and generalized ESF model of MAAP5.0.2. Also, we can eliminate the confusing concepts existed in the two models. So, it is judged that the newly developed MAAP5

  1. \\'Etude et traitement automatique de l'anglais du XVIIe si\\`ecle : outils morphosyntaxiques et dictionnaires

    CERN Document Server

    Piton, Odile

    2010-01-01

    In this article, we record the main linguistic differences or singularities of 17th century English, analyse them morphologically and syntactically and propose equivalent forms in contemporary English. We show how 17th century texts may be transcribed into modern English, combining the use of electronic dictionaries with rules of transcription implemented as transducers. Apr\\`es avoir expos\\'e la constitution du corpus, nous recensons les principales diff\\'erences ou particularit\\'es linguistiques de la langue anglaise du XVIIe si\\`ecle, les analysons du point de vue morphologique et syntaxique et proposons des \\'equivalents en anglais contemporain (AC). Nous montrons comment nous pouvons effectuer une transcription automatique de textes anglais du XVIIe si\\`ecle en anglais moderne, en combinant l'utilisation de dictionnaires \\'electroniques avec des r\\`egles de transcriptions impl\\'ement\\'ees sous forme de transducteurs.

  2. Evaluation of the Main Steam Line Break Accident for the APR+ Standard Design using MARS-KS

    Energy Technology Data Exchange (ETDEWEB)

    Park, M. H.; Kim, Y. S.; Hwang, Min Jeong; Sim, S. K. [Environment Energy Technology, Daejeon (Korea, Republic of); Bang, Young Seok [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2015-05-15

    As a part of licensing evaluation of the APR+ (Advanced Power Reactor +) standard design, Korea Institute of Nuclear Safety(KINS) performed safety evaluation of the APR+ Standard Safety Analysis Report(SSAR). The results of the safety evaluation of the APR+ Main Steam Line Break(MSLB) accident is presented for the most limiting post-trip return-to-power case with the single failure assumption of the Loss Of Offsite Power(LOOP). MARS-KS regulatory safety analysis code has been used to evaluate safety as well as the system behavior during MSLB accident. The MARS-KS analysis results are compared with the results of the MSLB safety analysis presented in the SSAR of the APR+. Independent safety evaluation has been performed using MARS-KS regulatory safety analysis code for the APR+ MSLB accident inside containment for the limiting case of the full power post-trip return-to-power. The results of MARS-KS analysis were compared with the results of the MSLB safety analysis presented in the APR+ SSAR. Due to higher cooldown of the MARS-KS analysis, the MARS-KS analysis results in a higher positive reactivity insertion into the core by the negative moderator and fuel temperature reactivity coefficients than the APR+ SSAR analysis. Both results show no return-to-power during the limiting case of the MSLB inside containment. However, APR+ SSAR moderator temperature reactivity insertion should be evaluated against the MARS-KS moderator density reactivity insertion for is conservatism. This study also clearly shows asymmetric thermal hydraulic behavior during the MSLB accident at intact and affected sides of the downcomer and the core. These asymmetric phenomena should be further investigated for the effects on the system design.

  3. Evaluation of the Main Steam Line Break Accident for the APR+ Standard Design using MARS-KS

    International Nuclear Information System (INIS)

    As a part of licensing evaluation of the APR+ (Advanced Power Reactor +) standard design, Korea Institute of Nuclear Safety(KINS) performed safety evaluation of the APR+ Standard Safety Analysis Report(SSAR). The results of the safety evaluation of the APR+ Main Steam Line Break(MSLB) accident is presented for the most limiting post-trip return-to-power case with the single failure assumption of the Loss Of Offsite Power(LOOP). MARS-KS regulatory safety analysis code has been used to evaluate safety as well as the system behavior during MSLB accident. The MARS-KS analysis results are compared with the results of the MSLB safety analysis presented in the SSAR of the APR+. Independent safety evaluation has been performed using MARS-KS regulatory safety analysis code for the APR+ MSLB accident inside containment for the limiting case of the full power post-trip return-to-power. The results of MARS-KS analysis were compared with the results of the MSLB safety analysis presented in the APR+ SSAR. Due to higher cooldown of the MARS-KS analysis, the MARS-KS analysis results in a higher positive reactivity insertion into the core by the negative moderator and fuel temperature reactivity coefficients than the APR+ SSAR analysis. Both results show no return-to-power during the limiting case of the MSLB inside containment. However, APR+ SSAR moderator temperature reactivity insertion should be evaluated against the MARS-KS moderator density reactivity insertion for is conservatism. This study also clearly shows asymmetric thermal hydraulic behavior during the MSLB accident at intact and affected sides of the downcomer and the core. These asymmetric phenomena should be further investigated for the effects on the system design

  4. Rôle des nanoparticules organiques dans le colmatage membranaire. Application au traitement d'eaux usées urbaines par bioréacteur à membranes

    OpenAIRE

    Teychené, Benoit

    2008-01-01

    Le traitement des eaux usées urbaines constitue une phase importante de la gestion globale des ressources en eau. Le bioréacteur à membranes est une option de choix pour répondre à cette demande. Ce procédé de traitement présente plusieurs avantages par rapport aux procédés classiques à boues activées mais reste confronté à l’un des problèmes majeurs de la filtration membranaire : le colmatage de la membrane. De nombreuses études ont mises en évidence l’impact néfaste sur la filtration de com...

  5. Une chaîne de traitement de l'information géographique au service de l'application de la loi Littoral

    Directory of Open Access Journals (Sweden)

    Patrick GUILLOPÉ

    1994-09-01

    Full Text Available L’application de la loi Littoral nécessitait une approche nouvelle de la part de l’État et la mise en œuvre d’outils nouveaux pour une gestion à long terme. L’apport de traitements automatiques de l’information géographique a été ainsi testé au CETE Normandie-Centre sur trois des grands principes posés par cette loi.

  6. Les stratégies de recherche et de traitement de l’information des futurs enseignants dans des environnements informatiques

    Directory of Open Access Journals (Sweden)

    Jean Loiselle

    2009-01-01

    Full Text Available [Français] L’article porte sur les stratégies de recherche et de traitement de l’information des futurs enseignants utilisant des environnements informatiques. Dix étudiantes terminant leur programme de formation à l’enseignement dans une université québécoise ont réalisé neuf activités de recherche et de traitement d’information dans des environnements informatiques. Les données recueillies renseignent sur les stratégies utilisées. Les résultats montrent que les participants utilisent des stratégies diversifiées à chacune des étapes du processus de recherche et de traitement de l’information, mais que ces stratégies ne sont pas toujours pertinentes. [English] This paper presents a study focusing on student teachers’ information searching and information processing strategies in Web-based environments. Ten student teachers completing their program performed nine information searching and processing tasks. Data collected through observation, thinking aloud process and interview showed a wide range of strategies throughout the completion of these tasks, but the study also highlights some shortfalls and limitations related to those strategies.

  7. Diverse Design Features of EU-APR1400 for Residual Heat Removal Function with Open RCS

    International Nuclear Information System (INIS)

    Diversity is the fundamental principle in safety system design of new nuclear power plants, which uses different mitigation measures to provide diverse ways of responding to a significant event. Regarding the diversity principle, EU-APR1400 (European APR1400) safety system should be in accordance with European design requirements. This paper provides how the core residual heat can be removed with open RCS (Reactor Coolant System) closure head condition using diverse cooling systems assuming a loss of SCS (Shutdown Cooling System). The loss of SCS results from a common cause failure of SCS or a loss of UHS (Ultimate Heat Sink). One of the postulated common cause failures which lead to the loss of SCS can be a manufacturing deficiency of shutdown cooling pumps, component cooling water pumps or essential service water pumps. The limiting event of the loss of SCS is the loss of UHS since the loss of UHS causes losses of safety systems including SCS, CCWS and ESWS. NO operator action inside the MCR (Main Control Room) during the first 30 minutes and outside the MCR during the first 60 minutes can be credited to recover the failed SCS. The diverse means of the EU-APR1400 for the residual heat removal function with RCS open condition have been developed to comply with the diversity principle of the European design requirements of new nuclear power plants. The results of the preliminary assessment show that the diverse design features are expected to satisfy the design criteria. In the future, more detailed design and assessment for this means will be performed considering interface requirements with completing the design of relevant systems and components

  8. Diverse Design Features of EU-APR1400 for Residual Heat Removal Function with Open RCS

    Energy Technology Data Exchange (ETDEWEB)

    Kweon, Hyeong Do; Lee, Keun Sung; Kim, Yong Soo; Kim, Sung Hwan [Korea Hydro and Nuclear Power Co., Ltd., Daejeon (Korea, Republic of)

    2014-05-15

    Diversity is the fundamental principle in safety system design of new nuclear power plants, which uses different mitigation measures to provide diverse ways of responding to a significant event. Regarding the diversity principle, EU-APR1400 (European APR1400) safety system should be in accordance with European design requirements. This paper provides how the core residual heat can be removed with open RCS (Reactor Coolant System) closure head condition using diverse cooling systems assuming a loss of SCS (Shutdown Cooling System). The loss of SCS results from a common cause failure of SCS or a loss of UHS (Ultimate Heat Sink). One of the postulated common cause failures which lead to the loss of SCS can be a manufacturing deficiency of shutdown cooling pumps, component cooling water pumps or essential service water pumps. The limiting event of the loss of SCS is the loss of UHS since the loss of UHS causes losses of safety systems including SCS, CCWS and ESWS. NO operator action inside the MCR (Main Control Room) during the first 30 minutes and outside the MCR during the first 60 minutes can be credited to recover the failed SCS. The diverse means of the EU-APR1400 for the residual heat removal function with RCS open condition have been developed to comply with the diversity principle of the European design requirements of new nuclear power plants. The results of the preliminary assessment show that the diverse design features are expected to satisfy the design criteria. In the future, more detailed design and assessment for this means will be performed considering interface requirements with completing the design of relevant systems and components.

  9. APR1400 l and C architecture with the advanced design feature including high reliability and maintainability

    International Nuclear Information System (INIS)

    The standard design of Advanced Power Reactor 1400 (APR1400) has been developed from 1992 to 2001 and obtained design certification from Korea Institute of Nuclear Safety (KINS) in 2002. The APR1400 standard design is being applied to the construction project of Shin-Kori 3, 4 nuclear power plants, which are scheduled to go into commercial operation in 2013 and 2014 respectively. Full digital I and C systems are adopted in safety and non-safety system of Shin-Kori 3, 4 to enhance safety and cost effectiveness of nuclear power plant. The NSSS/BOP control systems, which have been traditionally independent, are integrated in one DCS platform and one network to reduce the number of cabinets and improve system performance and maintainability. Safety grade I and C systems are designed to meet the regulatory requirements for real-time performance, reliability, single-failure criterion, independence, failure mode effect analysis (FMEA), defense-in-depth and diversity, deterministic control and communication, environmental qualification etc. Defense against common mode failure (CMF) of digital plant protection system is one of the key requirements in designing digital I and C systems. Diverse Protection System (DPS) is designed to be diverse from Plant Protection System (PPS) as a defense against common mode failure of digital plant protection system. Diverse manual ESF actuation is also designed to enforce plant safety against severe situation due to simultaneous all digital system failures of plant protection system. Currently, Shin-Kori 3,4 project is being constructed according to the detailed design based on standard design of APR1400 I and C system. Application of full digital I and C system in Shin-Kori 3,4 is expected to increase safety, reliability and maintainability. (authors)

  10. MARS calculation of PAFS (passive auxiliary feedwater system) heat exchanger in APR+

    International Nuclear Information System (INIS)

    APR+ (Advanced Power Reactor Plus), the next generation nuclear power plant in Korea, adopts PAFS (Passive Auxiliary Feedwater System) as one of the advanced safety feature. To design the condensation heat exchanger in PAFS, the two-phase flow phenomena in horizontal U-tube and PCCT (Passive Condensate Cooling Tank) were investigated by MARS calculation. By benchmarking with NOKO experimental result, MARS code showed a reasonable capability to quantitatively predict the condensation in horizontal tube heat exchanger. And the design of PAFS heat exchanger was proved to sufficiently remove the decay heat by the condensation heat transfer without any active auxiliary feedwater system

  11. MARS calculation of PAFS (passive auxiliary feedwater system) heat exchanger in APR+

    Energy Technology Data Exchange (ETDEWEB)

    Bae, Byoung Uhn; Yun, Byong Jo; Bae, Sung Won; Choi, Ki Yong; Song, Chul Hwa [KAERI, Daejeon (Korea, Republic of); Cheon, Jong [Korea Hydro and Nuclear Power Co., Daejeon (Korea, Republic of)

    2009-07-01

    APR+ (Advanced Power Reactor Plus), the next generation nuclear power plant in Korea, adopts PAFS (Passive Auxiliary Feedwater System) as one of the advanced safety feature. To design the condensation heat exchanger in PAFS, the two-phase flow phenomena in horizontal U-tube and PCCT (Passive Condensate Cooling Tank) were investigated by MARS calculation. By benchmarking with NOKO experimental result, MARS code showed a reasonable capability to quantitatively predict the condensation in horizontal tube heat exchanger. And the design of PAFS heat exchanger was proved to sufficiently remove the decay heat by the condensation heat transfer without any active auxiliary feedwater system.

  12. Probability of Neutralization Estimation for APR1400 Physical Protection System Design Effectiveness Evaluation

    International Nuclear Information System (INIS)

    It is focusing on development of a new designing process which can be compatible to international standards such as IAEA1 and NRC2 suggest. Evaluation for the design effectiveness was found as one of the areas to improve. If a design doesn't meet a certain level of effectiveness, it should be re-designed accordingly. The effectiveness can be calculated with combination of probability of Interruption and probability of neutralization. System Analysis of Vulnerability to Intrusion (SAVI) has been developed by Sandia National Laboratories for that purpose. With SNL's timely detection methodology, SAVI has been used by U.S. nuclear utilities to meet the NRC requirements for PPS design effectiveness evaluation. For the SAVI calculation, probability of neutralization is a vital input element that must be supplied. This paper describes the elements to consider for neutralization, probability estimation methodology, and the estimation for APR1400 PPS design effectiveness evaluation process. Markov chain and Monte Carlo simulation are often used for simple numerical calculation to estimate PN. The results from both methods are not always identical even for the same situation. PN values for APR1400 evaluation were calculated based on Markov chain method and modified to be applicable for guards/adversaries ratio based analysis

  13. Analysis of a 12-Finger Rod Drop using RETRAN/MASTER Code System for APR1400

    International Nuclear Information System (INIS)

    The Optimized Power Reactor 1000 (OPR1000) has 4-finger and 12-finger Control Element Assemblies (CEAs). When the 12-finger CEA is dropped, Core Protection Calculator System (CPCS) shuts down the reactor to prevent fuel damage that could occur from the sudden reactor power peaking. By contrast, the improved CPCS of Advanced Power Reactor 1400 (APR1400), which has systems similar to those of the OPR1000, decreases reactor power rapidly using its Reactor Power Cutback System (RPCS) to avoid unwanted reactor trips caused by the CPCS during a 12- finger CEA drop event. RETRAN is a best-estimate code for transient analysis of Non-LOCA. The RETRAN control logic, which includes the function of reducing reactor power during a 12-Finger CEA drop, has been developed for the APR1400. A MATRAN program has also been developed. MATRAN is the interface program for realtime processing to connect RETRAN with MASTER code which is a nuclear analysis and design code. MATRAN supplies adequate feedback reactivities from the MASTER code to RETRAN code. The purpose of this study is to analyze the behavior of a nuclear reactor core and its primary system using conventional RETRAN analysis procedure and MATRAN program analysis procedure during a 12- finger CEA drop. In addition, the axial power distribution and Axial Shape Index (ASI) are produced by the MATRAN program and they are confirmed as within operation limits

  14. Advanced Design Features of APR1400 and Realization in Shin Kori Construction Project

    International Nuclear Information System (INIS)

    APR1400 adopted several advanced design features. To ensure their proper operation as a part of ShinKori 3,4 project, both experimental and analytical work are continuing. In this paper, work on the advanced design features related to enhanced safety is examined. APR1400 safety injection system consists of four independent trains which include four safety injection pump and tanks. A passive flow regulating device called fluidic device is installed in the safety injection tanks. Separate effect tests including a full scale fluidic device tests have been conducted. Integral system tests are in progress. Combination of these work with the analytical work using RELAP5/Mod3 would ensure the proper operation of the new safety injection systems. To mitigate severe accidents, hydrogen mitigation system using PARs and igniters is adopted. Also, active injection system and the streamlined insulation design are adopted to enhance the in-vessel retention capability with the external cooling of RPV strategy. Analytic work with supporting experiments is performed. We are certain that these preparatory work would help the successful adaptation of ADF in ShinKori project. (authors)

  15. Probability of Neutralization Estimation for APR1400 Physical Protection System Design Effectiveness Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Myungsu; Lim, Heoksoon; Na, Janghwan; Chi, Moongoo [Korea Hydro and Nuclear Power Co. Ltd. Central Research Institute, Daejeon (Korea, Republic of)

    2015-05-15

    It is focusing on development of a new designing process which can be compatible to international standards such as IAEA1 and NRC2 suggest. Evaluation for the design effectiveness was found as one of the areas to improve. If a design doesn't meet a certain level of effectiveness, it should be re-designed accordingly. The effectiveness can be calculated with combination of probability of Interruption and probability of neutralization. System Analysis of Vulnerability to Intrusion (SAVI) has been developed by Sandia National Laboratories for that purpose. With SNL's timely detection methodology, SAVI has been used by U.S. nuclear utilities to meet the NRC requirements for PPS design effectiveness evaluation. For the SAVI calculation, probability of neutralization is a vital input element that must be supplied. This paper describes the elements to consider for neutralization, probability estimation methodology, and the estimation for APR1400 PPS design effectiveness evaluation process. Markov chain and Monte Carlo simulation are often used for simple numerical calculation to estimate P{sub N}. The results from both methods are not always identical even for the same situation. P{sub N} values for APR1400 evaluation were calculated based on Markov chain method and modified to be applicable for guards/adversaries ratio based analysis.

  16. Experimental study on the operational and the cooling performance of the APR+ passive auxiliary feedwater system

    International Nuclear Information System (INIS)

    The passive auxiliary feedwater system (PAFS) is one of the advanced safety features adopted in the APR+ which is intended to completely replace the conventional active auxiliary feedwater system. The PAFS cools down the steam generator secondary side and eventually removes the decay heat from the reactor core by introducing a natural driving force mechanism; i.e., condensing steam in nearly-horizontal U-tubes submerged inside the passive condensation cooling tank (PCCT). With an aim of validating the cooling and operational performance of the PAFS, the separate effect test, PASCAL (PAFS Condensing Heat Removal Assessment Loop), is being performed to experimentally investigate the condensation heat transfer and natural convection phenomena in the PAFS. A single nearly-horizontal U-tube whose dimension is same as the prototypic U-tube of the APR+ PAFS is simulated in the PASCAL test. By performing the PASCAL test, the major thermal-hydraulic parameters such as local/overall heat transfer coefficients, fluid temperature inside the tube, wall temperature of the tube, and pool temperature distribution in the PCCT were produced not only to evaluate the current condensation heat transfer model but also to present database for the safety analysis related with the PAFS. (authors)

  17. Detection of the apr gene in proteolytic psychrotrophic bacteria isolated from refrigerated raw milk.

    Science.gov (United States)

    Martins, Maurilio L; de Araújo, Elza F; Mantovani, Hilário C; Moraes, Célia A; Vanetti, Maria C D

    2005-07-15

    Bacteria of the genus Pseudomonas have been associated with the spoilage of raw milk and dairy products due to the production of thermostable proteolytic enzymes. The apr gene encodes for alkaline metalloprotease in Pseudomonas and other related bacteria. Its presence in psychrotrophic proteolytic bacteria isolated from raw milk collected from cooling tanks was verified. A polymerase chain reaction (PCR) technique was used with degenerate primers. Total DNA from 112 isolates was pooled in different groups and then used as template for the amplification reactions. Controls consisted of DNA extracted from 26 cultures. An expected DNA fragment of 194 bp was detected in groups that contained bacteria identified as Pseudomonas. The PCR product was observed only when DNA from control cultures of Pseudomonas aeruginosa, Pseudomonas fluorescens, Serratia marcescens and Aeromonas hydrophila were used. A detection limit assay indicated that the apr gene could be directly amplified from pasteurized milk inoculated with 10(8) CFU/ml of P. fluorescens. With this method it was possible to detect proteolytic bacteria at 10(5) CFU/ml in reconstituted skim milk powder if cells were recovered for DNA extraction before amplification. PMID:15992619

  18. Thermal-hydraulic tests and analyses for the APR1400's development and licensing

    International Nuclear Information System (INIS)

    The program on Thermal-Hydraulic Evaluation by Testing and Analysis (THETA) for the development and licensing of the new design features in the APR1400 (Advanced Power Reactor-1400) is briefly introduced with a presentation on the research motivation and typical results of the separate effect tests and analyses of the major design features. The first part deals with multi-dimensional phenomena related to the safety analysis of the APR1400. One research area is related to the multi-dimensional behavior of the Safety Injection (SI) water in a reactor pressure vessel downcomer that uses a direct vessel injection type of SI system. The other area is associated with the condensation of steam jets and the resultant thermal mixing in a water pool; these phenomena are relevant to the depressurization of a Reactor Coolant System (RCS). The second part describes our efforts to develop new components for safety enhancements, such as a fluidic device as a passive SI flow controller and a sparger to depressurize the RCS. This work contributes to an understanding of the new thermal-hydraulic phenomena that are relevant to advanced reactor system designs; it also improves the prediction capabilities of analysis tools for multi-dimensional flow behavior, especially in complicated geometries

  19. L’étude et le traitement judiciaire de la récidive à Chicago, 1920 – 1940

    Directory of Open Access Journals (Sweden)

    Marie Fleck

    2008-11-01

    Full Text Available Les méthodes actuarielles ont un rôle croissant dans le traitement judiciaire de la récidive aux Etats-Unis, avec le développement du profilage criminel appliqué par la police ou des guides à la décision (guidelines proposés aux juges et aux contrôleurs judiciaires. Une visite historique des travaux sociologiques de l’Ecole de Chicago (1920-1940 nous permet de mieux comprendre la situation actuelle. Elle nous invite à reconsidérer leurs principales contributions méthodologiques,l’approche complémentaire des méthodes actuarielles et cliniqueset leurs préoccupations sur  leurs conditions d’usage.Actuarial methods have an increasing role in the judicial treatment of recidivism in United States, with the development of criminal profiling applied by law enforcement officers, sentencing guidelines for trial judges and prognosis intended to probation and parole officers. Revisiting the works on parole of Chicago sociologists in 1920-40 would enable us to understand better the current situation; it invites us to reconsider their main methodological contributions, which are the complementary approach of actuarial and clinical methods and their concern about their conditions of use.

  20. Après-Coup in French Psychoanalysis: The Long Afterlife of Nachträglichkeit: The First Hundred Years, 1893 to 1993.

    Science.gov (United States)

    House, Jonathan; Slotnick, Julie

    2015-10-01

    Après-coup finds its origins in Freud's earliest psychoanalytic writings, but it was only half a century ago that French psychoanalysts rediscovered, clarified, and developed the concept and so brought it recognition as an essential Freudian concept. Because the history of après-coup is embedded in the French reading of Freud, this article will give an account of that reading in relation to après-coup. PMID:26485487

  1. Evaluation of Effect of N2 Gas on the Cooling Capability of Passive Auxiliary Feedwater System (PAFS) in APR+

    International Nuclear Information System (INIS)

    In Korea, Advanced Power Reactor Plus (APR+) has being developed by adding passive safety features to Advanced Power Reactor 1400MWe (APR1400). Passive Auxiliary Feedwater System (PAFS) is one of passive system adopted in the APR+ to replace the conventional active auxiliary feedwater system. Because PAFS removes decay heat from the reactor core, it is required to verify the performance of PAFS in postulated accidents cases. In addition, an effect of noncondensable gas on the heat removal capability of PAFS should be evaluated since the non-condensable gas may deteriorate a condensation heat transfer through the condensation heat exchanger in PAFS. In this study, the effect of N2 gas was evaluated using MARS

  2. Le Rituximab dans le traitement de la polyarthrite rhumatoïde réfractaire aux inhibiteurs du facteur de nécrose tumorale (TNF)-Alpha

    OpenAIRE

    Brulhart, Laure Sophie

    2009-01-01

    Ces dernières années, le développement de traitements biologiques ciblés a dramatiquement modifié la prise en charge de la polyarthrite rhumatoïde (PR). Parmi ces traitements, les inhibiteurs du TNF-a (anti-TNF-a) ont été les premiers validés. Mais environ 30% des patients ont une réponse insatisfaisante à ces molécules. Dans un premier temps, une étude ouverte a permis évaluer l'efficacité du Rituximab, traitement dirigé contre les lymphocytes B, pour la prise en charge de patients avec une ...

  3. Study of the dry processing of uranium ores; Etude des traitements de minerais d'uranium par voie seche

    Energy Technology Data Exchange (ETDEWEB)

    Guillet, H

    1959-02-01

    A description is given of direct fluorination of pre-concentrated uranium ores in order to obtain the hexafluoride. After normal sulfuric acid treatment of the ore to eliminate silica, the uranium is precipitated by a load of lime to obtain: either impure calcium uranate of medium grade, or containing around 10% of uranium. This concentrate is dried in an inert atmosphere and then treated with a current of elementary fluorine. The uranium hexafluoride formed is condensed at the outlet of the reaction vessel and may be used either for reduction to tetrafluoride and the subsequent manufacture of uranium metal or as the initial product in a diffusion plant. (author) [French] Il s'agit d'une description de fluoration directe de preconcentres de minerais d'uranium en vue d'obtention d'hexafluorure. Apres attaque sulfurique normale du minerai, afin d' eliminer la silice, l' uranium est precipite par un toit de chaux pour obtenir: ou uranate de chaux impur de titre moyen, ou uranium de la dizaine du pourcentage. Ce concentre seche en atmosphere inerte est soumis a un courant de fluor elementaire. L'hexafluorure d'uranium forme est condense a la sortie du reacteur et peut etre utilise soit apres reduction en tetrafluorure par l'elaboration d'uranium metal, soit comme produit de base dans le cadre d'une usine de diffusion. (auteur)

  4. Thermal-hydraulic evaluation of passive containment cooling system of improved APR+ during LOCAs

    Energy Technology Data Exchange (ETDEWEB)

    Jeon, Byong Guk; NO, Hee Cheon, E-mail: hcno@kaist.ac.kr

    2014-10-15

    Highlights: • Larger air holdup tanks are confirmed to be needed for PCCS through MARS simulation. • Condensation model in MARS gives lower heat transfer than Dehbi's correlation. • Heat transfer resistance of steam–air mixture is dominant for PCCS tubes. • Heat sink structures remove dominant amount of decay heat initially. • Flow instability is eased at higher tube inlet form loss, return level, and angle. - Abstract: Various reactor concepts and technologies have been devised and evaluated to ensure the integrity of the core and the containment under a prolonged station blackout. After the successful validation of the passive auxiliary feedwater system (PAFS) of Advanced Power Reactor Plus (APR+), Korea is considering an improved APR+ with a passive containment cooling system (PCCS). In a previous paper, we suggested a PCCS design based on APR+ and performed a scoping analysis. We performed a MARS simulation for the thermal hydraulic evaluation of the system behavior, including natural circulation through the Passive Condensation Cooling Tank (PCCT) water pool and inside PCCS tubes as well as steam–air mixture condensation inside the containment. Through a simulation using the MARS system code, we investigated the effect of air holdup tanks (AHTs) on reduction of the air fraction in the containment, the effects of several steam–air mixture condensation models, the role of heat structures, and the flow instability inside the PCCS tubes. We found that the presence of AHT reduced the number of required PCCS tubes by more than half and the heat resistance of the steam–air mixture side is dominant in terms of governing the overall performance of PCCS. The embedded MARS condensation model and Uchida's correlation gave lower heat transfer coefficients than Dehbi's correlation, and heat structures removed more decay heat than PCCS tubes. Finally, intense flow instability inside the PCCS tubes was observed and was mitigated by placing

  5. Le Chaebol après la crise financière de 1997

    Directory of Open Access Journals (Sweden)

    Chung-Yeol Park

    2008-11-01

    Full Text Available L’objet de cet article est de présenter les mutations subies par les Chaebols à la suite de la crise financière de 1997. La première section est consacrée à un bref rappel de la formation et du développement des Chaebols, ainsi qu’à une caractérisation des attributs de leur forme organisationnelle. Il s’agit ainsi d’indiquer la « forme  canonique » que revêtait le Chaebol avant la crise, afin de fixer des repères pour mesurer et évaluer l’ampleur et la nature des mutations intervenues après la crise de 1997. La deuxième et la troisième section proposent une analyse de la réforme financière et de la réforme du secteur des entreprises conduites en Corée après 1997 et largement influencées par le FMI. La quatrième section présente une analyse concrète des changements au sein de deux Chaebols majeurs (Hyundai et Samsung depuis la crise financière. A partir de ces études de cas et de données empiriques complémentaires sont mis en évidence tout à la fois les changements et la permanence dans la structure et le comportement des Chaebols, suite aux modifications institutionnelles introduites après la crise financière de 1997.The Chaebol after the 1997. Financial Crisis Changes and Continuity. The paper presents the changes undergone by the Korean Chaebols after the financial crisis of 1997. The first section shortly recalls the history of the birth and development of the Chaebols and presents their specific organizational traits.  The second and third sections are dedicated to the presentation of the financial reforms and of the reforms of the enterprises implemented in Korea after 1997. The fourth section presents two cases studies of the changes introduced after 1997 on two major chaebols : Hyundai Group and Samsung Group. These case studies and other more general empirical data are used to evaluate both the changes and the continuity in Chaebol’s organizational forms and behaviours after the 1997

  6. Analysis of Heat Removal Capability of PAFS (Passive Auxiliary Feedwater System) in APR (Advanced Power Reactor Plus)

    International Nuclear Information System (INIS)

    As passive safety features for nuclear power plants receive increasing attention, South Korea has designed PAFS (Passive Auxiliary Feedwater System) for APR+ (Advanced Power Reactor Plus). Because the PAFS replaces a conventional active auxiliary feedwater system and plays a role in the ultimate heat sink for decay heat, it is necessary to evaluate the heat removal capability of PAFS under postulated accidents conditions. Therefore, the performance analysis is carried out for two accident cases: Loss of Condenser Vacuum (LOCV) and Feedwater Line Break (FLB) accidents. For the analysis, MARS-KS code is used and MARS-KS model is developed by adding PAFS model to the existing APR1400 model

  7. Analysis of Heat Removal Capability of PAFS (Passive Auxiliary Feedwater System) in APR (Advanced Power Reactor Plus)

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Y. J.; Kang, K. H.; Yun, B. J. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2012-03-15

    As passive safety features for nuclear power plants receive increasing attention, South Korea has designed PAFS (Passive Auxiliary Feedwater System) for APR+ (Advanced Power Reactor Plus). Because the PAFS replaces a conventional active auxiliary feedwater system and plays a role in the ultimate heat sink for decay heat, it is necessary to evaluate the heat removal capability of PAFS under postulated accidents conditions. Therefore, the performance analysis is carried out for two accident cases: Loss of Condenser Vacuum (LOCV) and Feedwater Line Break (FLB) accidents. For the analysis, MARS-KS code is used and MARS-KS model is developed by adding PAFS model to the existing APR1400 model.

  8. La fibrillation atriale, fréquence, facteurs étiologiques, évolution et traitement dans un service de cardiologie de Dakar, Sénégal

    Directory of Open Access Journals (Sweden)

    Kane Abdoul

    2010-09-01

    Full Text Available INTRODUCTION: La fibrillation atriale est le trouble du rythme cardiaque soutenu le plus fréquent. Les objectifs de ce travail étaient d’étudier la fréquence, les facteurs étiologiques, l’évolution et le traitement de la fibrillation atriale dans un service de cardiologie de Dakar au Sénégal. METHODES: Il s’agit d’une étude rétrospective réalisée sur cinq ans et portant sur l’analyse de 150 dossiers de patients hospitalisés pour une fibrillation atriale. RESULTATS: La fréquence de la fibrillation atriale était de 5,35 % et représentait 66% des troubles du rythme cardiaque avec une prédominance féminine (sex-ratio H/F = 0,45 et un âge moyen de 57,06 ± 18,64 ans. L’origine de la fibrillation était valvulaire dans 36,7% des cas. Les complications thromboemboliques étaient plus fréquentes dans la fibrillation atriale non valvulaire (p=0,006, chez les sujets d’âge > 50 ans (p=0,01 et en cas de dilatation de l’oreillette gauche (p=0,05. Une anticoagulation par anti-vitamine K était instaurée dans 62% des cas et un traitement de contrôle de la fréquence cardiaque dans 87,33%. CONCLUSION: La fibrillation atriale est fréquente en milieu hospitalier africain et concerne des sujets relativement jeunes. L’hypertension artérielle et les valvulopathies rhumatismales sont les principaux facteurs étiologiques. Le traitement reste essentiellement médicamenteux par contrôle de la fréquence cardiaque.

  9. Colloque final du programme de recherche ECHIBIOTEB : Outils innovants d’échantillonnage, d’analyses chimiques et biologiques pour le suivi de traitements avancés des eaux usées et des boues

    OpenAIRE

    Miege, C.; Choubert, J.M.; Geffard, O.; Coquery, M.; Bruchet, A.; Besnault, S.; H. Budzinski; Cachot, J.; Parlanti, E; Ait Aissa, S.; Pandard, P.; Levi, Y; Dudal, Y.

    2015-01-01

    / Résumé du programme ECHIBIOTEB : Bien que les stations de traitement des eaux usées (STEU) ne soient pas construites dans le but d’éliminer les micropolluants organiques et métalliques, ces derniers peuvent néanmoins être éliminés de la phase dissoute des eaux usées par les procédés de traitement biologique conventionnels. L’élimination peut se faire grâce aux mécanismes d’adsorption sur les boues ou de dégradation biologique ou abiotique. Cependant, certains micropolluant...

  10. New tools for NTD vaccines: A case study of quality control assays for product development of the human hookworm vaccine Na-APR-1M74.

    Science.gov (United States)

    Pearson, Mark S; Jariwala, Amar R; Abbenante, Giovanni; Plieskatt, Jordan; Wilson, David; Bottazzi, Maria Elena; Hotez, Peter J; Keegan, Brian; Bethony, Jeffrey M; Loukas, Alex

    2015-01-01

    Na-APR-1(M74) is an aspartic protease that is rendered enzymatically inactive by site-directed mutagenesis and is a candidate antigen component in the Human Hookworm Vaccine. The mutant protease exerts vaccine efficacy by inducing antibodies that neutralize the enzymatic activity of wild type enzyme (Na-APR-1wt) in the gut of the hookworm, thereby depriving the worm of its ability to digest its blood meal. Previously, canines immunized with Na-APR-1(M74) and challenged with Ancylostoma caninum were partially protected against hookworm challenge infection, especially from the loss in hemoglobin observed in control canines and canine immunoglobulin (Ig) G raised against Na-APR-1 was shown to inhibit the enzymatic activity of Na-APR-1 wt in vitro, thereby providing proof of concept of Na-APR-1(M74) as a vaccine antigen. The mutated version, Na-APR-1(M74), was then expressed at the cGMP level using a Nicotiana benthamiana expression system (Fraunhofer, CMB, Delaware, MD), formulated with Alhydrogel®, and used to immunize mice in a dose-ranging study to explore the enzyme-neutralizing capacity of the resulting anti- Na-APR-1(M74) IgG. As little as 0.99 μg of recombinant Na-APR-1(M74) could induce anti Na-APR-1(M74) IgG in mice that were capable of inhibiting Na-APR-1w t-mediated digestion of a peptide substrate by 89%. In the absence of enzymatic activity of Na-APR-1(M74) as a surrogate marker of protein functionality, we developed an assay based on the binding of a quenched fluorescence-labeled inhibitor of aspartic proteases, BODIPY-FL pepstatin A (BDP). Binding of BDP in the active site of Na-APR-1 wt was demonstrated by inhibition of enzymatic activity, and competitive binding with unlabelled pepstatin A. BDP also bound to Na-APR-1(M74) which was assessed by fluorescence polarization, but with an ∼ 50-fold reduction in the dissociation constant. Taken together, these assays comprise a "toolbox" that could be useful for the analyses of Na-APR-1(M74) as it

  11. A MARS and MIDAS Linked Accident Simulation for Large LOCA in APR1400

    International Nuclear Information System (INIS)

    A linked calculation utilizing the design-basis code MARS and the severe accident code MIDAS has been accomplished for a station blackout simulation in APR1400. The MARS code was developed by using the RELAP3/MOD3 and COBRA-TF codes, while the MIDAS code is currently under a development process using the MELCOR code. The objectives of this paper are to explain how to identify the MAR-MIDAS linked calculation outlines and the technical problems, including the MARS data transfer method, the MIDAS input generation works and so on. For the performance verification of the MARS-MIDAS linked calculation, the MARS, MIDAS and their linkage system are run independently for the same initiating event, so that their data can be compared with each other after the selection of proper variables

  12. A MARS and MIDAS Linked Accident Simulation for Large LOCA in APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Young; Kim, K. R.; Kim, D. H.; Chung, B. D. [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    2006-07-01

    A linked calculation utilizing the design-basis code MARS and the severe accident code MIDAS has been accomplished for a station blackout simulation in APR1400. The MARS code was developed by using the RELAP3/MOD3 and COBRA-TF codes, while the MIDAS code is currently under a development process using the MELCOR code. The objectives of this paper are to explain how to identify the MAR-MIDAS linked calculation outlines and the technical problems, including the MARS data transfer method, the MIDAS input generation works and so on. For the performance verification of the MARS-MIDAS linked calculation, the MARS, MIDAS and their linkage system are run independently for the same initiating event, so that their data can be compared with each other after the selection of proper variables.

  13. Schemes of a MARS and MIDAS linked simulation for SBO in APR1400

    International Nuclear Information System (INIS)

    A linked calculation utilizing the design-basis code MARS and the severe accident code MIDAS has been accomplished for a station blackout simulation in APR1400. The MARS code was developed by using the RELAP3/MOD3 and COBRA-TF codes, while the MIDAS code is currently under a development process using the MELCOR code. In this paper, the MAR-MIDAS linked calculation outlines and the technical problems are presented, including the MARS data transfer method, the MARS and MIDAS node mapping and variable definition principles, the MIDAS input generation works and so on. For the performance verification of the MARS-MIDAS linked calculation, the MARS, MIDAS and their linkage system are run independently for the same initiating event, so that their data can be compared with each other after the selection of proper variables. (author)

  14. Signoles Aude, Le Hamas au pouvoir et après ?, Toulouse, Editions Milan, 2006.

    Directory of Open Access Journals (Sweden)

    Jean-François Legrain

    2007-11-01

    Full Text Available Dans les étroites limites imposées par la collection (absence totale de notes et de bibliographie, 112 p. en format réduit, le petit livre d’Aude Signoles, Le Hamas au pouvoir et après ?, commence à combler un vide de l’édition française. Le seul livre jusque là disponible en français et entièrement consacré à Hamas remonte à 7 années maintenant ; doté de nombreuses erreurs factuelles et faisant comme si Hamas était apparu avec l’autonomie des années 1990, il ignorait tout de son passé d’Ass...

  15. Study on MELCOR Modeling for Emergency External Water Injection Scenario of SBO in APR1400

    International Nuclear Information System (INIS)

    In the present study, a MELCOR model for APR1400 was developed and applied to analyze a SBO scenario selected to confirm the effectiveness of the means. In this analysis, the primary and secondary emergency cooling water injection were considered. Leakage from the Reactor Coolant Pump (RCP) seal and opening of the Atmosphere Dump Valve (ADV) were modeled as well to simulate the external pump injection strategy. In this study, the analysis results showed that the external injection strategy with an ADV manual opening could successfully cool down the reactor for a station blackout accident through its effective implementation. It was found that the RCP seal leakage rate is a sensitive parameter for depressurization of the RCS. In this regard, further study is needed to develop a realistic RCP seal leakage model, referring to detailed technical data

  16. Reliability analysis of protection system of advanced pressurized water reactor - APR 1400

    International Nuclear Information System (INIS)

    Reliability analysis was carried out for the protection system of the Korean Advanced Pressurized Water Reactor - APR 1400. The main focus of this study was the reliability analysis of digital protection system, however, towards giving an integrated statement of complete protection reliability an attempt has been made to include the shutdown devices and other related aspects based on the information available to date. The sensitivity analysis has been carried out for the critical components / functions in the system. Other aspects like importance analysis and human error reliability for the critical human actions form part of this work. The framework provided by this study and the results obtained shows that this analysis has potential to be utilized as part of risk informed approach for future design / regulatory applications

  17. Assessment of fluid flow characteristics for fluidic device in APR 1400

    International Nuclear Information System (INIS)

    New evolutionary light water reactors (LWRs) are being developed all over the world today. Some of those LWRs employ so-called passive safety components that use natural phenomena as the driving force such as expansion of pressurised gas, natural circulation, and so forth. These passive safety components and their systems are applied to improve the safety of nuclear power plants, further achieving not only to simplify the safety system, but also to improve its reliability and to provide a sufficient time margin to enable the operators to cope with accidents. The APR 1400 (Advanced Pressurised Water Reactor), which is a Korean Next Generation Reactor, adopted fluidic device as one of its passive pieces of safety equipment. The fluidic device is installed at the bottom of the inner space of the Safety Injection Tank (SIT) to control the flow rate of emergency cooling water during a large break loss of coolant accident (LBLOCA). During the past two years, a scale model test to obtain the required flow characteristics of the device under the APR 1400 specific conditions has been performed in Korea. The performance verification test was conducted to obtain the optimum characteristics and design data of full fluidic device (FD). In this study, the thermal-hydraulic characteristics for the fluidic device are analysed using SIMPLE algorithm with an aim to develop the assessment and verification guidelines for the APR 1400. To assess the flow characteristics for fluidic device, a three dimensional numerical model is developed and its results are compared with those of experiments. The fluid flow characteristics of the FD, which is passive flow control device in the SIT of APR-1400 are assessed using SIMPLE algorithm using FLUENT code and are compared with the experimental results. In this study, the fluid flow rate and pressure in the FD are predicted on the basis of the boundary condition at the entrance of supply port, control port, and discharge port respectively, so as

  18. Marrakech, un mois plus tard, 10 ans après

    Directory of Open Access Journals (Sweden)

    Bernard Debarbieux

    2011-06-01

    Full Text Available Il y a bientôt un mois, la place Jemma el Fna, dans la médina de Marrakech, et tout Marrakech avec elle, étaient secouées par un attentat terroriste. La ville en parle intensément, dans les rues, dans les cafés, dans les journaux. Il y a 10 ans, cette même place entrait dans le cercle des sites du patrimoine Mondial de l'Humanité. Jemma el Fna retentit cette semaine des festivités organisées pour célébrer cet anniversaire. La fête après le drame ? Comme pour oublier ? Certainement pas. Toujou...

  19. Development and Verification of MAAP5.0.3 Parameter file for APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Mi Ro; Kim, Hyeong Taek [KHNP-CRI, Daejeon (Korea, Republic of)

    2015-05-15

    After the Fukushima accident, EPRI has continuously upgrade the MAAP5 (Modular Accident Analysis Program version 5) that is expected to expand the limitation of MAAP4. As a result of those efforts, the MAAP5.0.2 (Build 5020000) was released officially in December, 2013. Also, in August, 2014, the newest version of MAAP5, MAAP 5.0.3 (Build 5030000), was officially released. The parameter file development is essential for severe accident analysis using MAAP code for specific plant. In 2014, KHNP developed the first draft version of MAAP 5.0.2 parameter file for APR1400 type NPP and had tested for some basic severe accident sequence. And, until now, KHNP has continuously complemented the first draft version of APR1400 type NPP parameter file for MAAP 5.0.2 and 5.0.3. In this study, we analysis the MCCI phenomena using MAAP 5.0.3 version with the 2''n''d draft version of APR1400 parameter file developed by KHNP. The purpose of this study is to compare the major difference in MAAP 5.0.2 and 5.0.3 MCCI model and to verify the appropriateness of the 2''n''d draft version of parameter file. The MCCI phenomena have been controversial issues in the severe accident progression, so there have been great efforts to solve them until now. As the part of these efforts, EPRI published MAAP 5.0.3 version which is known that the 'Lower head plenum model' and the 'MCCI model' was upgraded. KHNP have the plan in order to upgrade the old parameter file based on MAAP4 to that based on MAAP5.0.2 or higher version for all domestic nuclear power plants. So, we have continuously developed the MAAP 5.0.2 and 5.0.3 parameter file for APR1400 type NPP. In this study, we analyzed the MCCI phenomena using MAAP 5.0.3 and 2''n''d draft version parameter file. And we found some insight as belows; (1) The Melt Eruption Model can greatly affect the MCCI progression only in the case of limestone concrete in the wet cavity

  20. Vertical Seismic Responses of Seismically Isolated APR1400 Structures supported by Laminated Rubber Bearings

    International Nuclear Information System (INIS)

    The low horizontal shear stiffness of the isolator bearing is, typically, accompanied by large lateral displacements in the seismically isolated system. These large lateral displacements might lead to reductions in the vertical stiffness of the elastomeric or lead.rubber bearing (LRB). This paper summarizes the analytical study results performed with APR1400 model isolated with LRBs aimed at investigating the influence of vertical ground motion. Three types of earthquake motions are used as input motion. Floor response spectra are computed at the specific points of the structure to compare the vertical responses of seismically isolated structure to those of fixed base structure. The vertical responses of seismically isolated structure with LRBs might be increased than in the fixed base structure. This fact should be considered in the design stage. The vertical stiffness of the LRB should be reasonably estimated to design a seismically isolated nuclear structure

  1. Development and Verification of MAAP5.0.3 Parameter file for APR1400

    International Nuclear Information System (INIS)

    After the Fukushima accident, EPRI has continuously upgrade the MAAP5 (Modular Accident Analysis Program version 5) that is expected to expand the limitation of MAAP4. As a result of those efforts, the MAAP5.0.2 (Build 5020000) was released officially in December, 2013. Also, in August, 2014, the newest version of MAAP5, MAAP 5.0.3 (Build 5030000), was officially released. The parameter file development is essential for severe accident analysis using MAAP code for specific plant. In 2014, KHNP developed the first draft version of MAAP 5.0.2 parameter file for APR1400 type NPP and had tested for some basic severe accident sequence. And, until now, KHNP has continuously complemented the first draft version of APR1400 type NPP parameter file for MAAP 5.0.2 and 5.0.3. In this study, we analysis the MCCI phenomena using MAAP 5.0.3 version with the 2''n''d draft version of APR1400 parameter file developed by KHNP. The purpose of this study is to compare the major difference in MAAP 5.0.2 and 5.0.3 MCCI model and to verify the appropriateness of the 2''n''d draft version of parameter file. The MCCI phenomena have been controversial issues in the severe accident progression, so there have been great efforts to solve them until now. As the part of these efforts, EPRI published MAAP 5.0.3 version which is known that the 'Lower head plenum model' and the 'MCCI model' was upgraded. KHNP have the plan in order to upgrade the old parameter file based on MAAP4 to that based on MAAP5.0.2 or higher version for all domestic nuclear power plants. So, we have continuously developed the MAAP 5.0.2 and 5.0.3 parameter file for APR1400 type NPP. In this study, we analyzed the MCCI phenomena using MAAP 5.0.3 and 2''n''d draft version parameter file. And we found some insight as belows; (1) The Melt Eruption Model can greatly affect the MCCI progression only in the case of limestone concrete in the wet cavity

  2. Analysis Of Control Rod Ejection Of APR1400 By RELAP5

    International Nuclear Information System (INIS)

    This paper presents the analysis of Reactivity Induced Accident caused by ejection of a Control Element Assembly (CEA) from APR 1400 reactor vessel within 0.05 second. The initial condition were assumed as following: power level at 102%, delayed neutron fraction β = 412 pcm and CEA worth = 110 pcm. The analysis was simulated by RELAP5 code through two step: calculation of steady state and calculation of transient with initial condition mentioned as above. Some output results were presented with explanation: sequence of events corresponding to the time of the accident, the system behavior as power, reactivity feedback from fuel temperature changes (Doppler) as well as temperature, pressure, DNBR within 6 second of the accident. (author)

  3. Analysis Of Feedwater Line Break Of APR1400 By MARS Code

    International Nuclear Information System (INIS)

    This paper will deal with analysis of Feed water Line Break problem (FWLB) of the APR 1400 NPP with initial conditions: operation at 100% of power, double-ended break area of 0.058 m2 and the break location of the feedwater line between the check valve and the steam generator. The analysis was simulated by MARS code through two step: calculation for steady state and calculation for transient state with initial condition mentioned. Some output result were presented with explanation: sequence of events corresponding to the time of the accident, the system behavior as temperature, pressure, steam generator water levels as well as DNBR, etc. before and after the accident. (author)

  4. Approche anthropologique des déterminants de l'observance dans le traitement de l'hypertension artérielle

    OpenAIRE

    Sarradon-Eck, Aline; Egrot, Marc; Blanc, Marie-Anne; Faure, Murielle

    2008-01-01

    La revue Pratiques et organisation des soins (en ligne) porte le numéro ISSN : 1961 - 9391Revue en ligne et en libre accès : http://www.ameli.fr/l-assurance-maladie/statistiques-et-publications/la-revue-pratiques-et-organisation-des-soins/Article disponible en ligne sur le site de la revue : http://www.ameli.fr/fileadmin/user_upload/documents/Observance_du_traitement_de_l_hypertension_01.pdf Aim: Uncontrolled hight blood pressure leads clinicians to wonder about adherence degree amongst hy...

  5. Edition critique d'un court article d'André-Georges Haudricourt: "Le traitement des spirantes lors de la mutation des initiales"

    OpenAIRE

    Haudricourt, André-Georges; Ferlus, Michel

    2013-01-01

    This document is a critical edition of a short article by Haudricourt: Haudricourt, André-Georges. 1979. "Le traitement des spirantes lors de la mutation des initiales." In Therapan L. Thongkum, V. Panupong, P. Kullavanijaya & Kalaya Tingsabadh (eds.), Studies in Tai and Mon-Khmer phonetics and phonology in honor of Eugénie J.A. Henderson, pp. 105-110. Bangkok: Chulalongkorn University Press. Michel Ferlus explains and expands the line of reasoning set out by André-Georges Haudricourt. Ce ...

  6. Mieux traiter le diabète : combattre l’inertie et améliorer l’adhésion au traitement.

    OpenAIRE

    Scheen, André; Philips, Jean-Christophe; Paquot, Nicolas

    2010-01-01

    Le diabète est une maladie chronique par excellence. Comme beaucoup d’autres maladies chroniques, le diabète, qu’il soit de type 1 ou plus encore de type 2, est d’origine complexe, combinant l’infl uence de facteurs génétiques et environnementaux. Le but du traitement est de corriger au mieux l’hyperglycémie chronique, mais aussi d’autres facteurs de risque (hypertension artérielle, hypercholestérolémie,…), de façon à prévenir la survenue de complications, garantir une...

  7. La méthanisation des boues issues du traitement des eaux usées : comparaison des performances de 3 technologies différentes

    OpenAIRE

    Reverdy, A.L.; Baudez, J.C.; Dieudé-Fauvel, E.

    2011-01-01

    / La valorisation du biogaz est une technologie en développement et qui présente un fort potentiel en France. Ce biogaz peut avoir diverses origines telles que la méthanisation des boues issues du traitement des eaux usées. Cependant, en France, ces installations sont peu nombreuses (seulement 68 stations de plus de 30 000EH). Ces technologies de méthanisation sont la plupart du temps identiques : un grand réacteur dans lequel des boues chauffées à 37°C sont introduites et sont brassées...

  8. Preliminary Analysis of Ex-Vessel Steam Explosion using TEXAS-V code for APR1400

    International Nuclear Information System (INIS)

    The purpose of this study is to explore input development and the audit calculation using TEXAS-V code for ex-vessel steam explosion for a flooded reactor cavity of APR1400. TEXAS computational models are one of the simplified tools for simulations of fuel-coolant interaction during mixing, triggering and explosion phase. The models of TEXAS code were validated by performing the fundamental experimental investigation in the KROTOS facility at JRC, Ispra. The experiments such as KROTOS and FARO experiment are aimed at providing benchmark data to examine the effect of fuel-coolant initial conditions and mixing on explosion energetics with alumina and prototypical core material. TEXAS-V code used in this study was to analyze and predict the ex-vessel steam explosion for a reactor scale. The input deck to simulate the flooded reactor cavity of APR1400 is developed and base case calculation is performed. This study will provide a base for further study. The code will be of use for the evaluation and sensitivity study of ex-vessel steam explosion for ERVC strategy in the future studies. Analysis result of this study is similar to the result of other study. Through this study, it is found that TEXAS-V could be the used as a tool for predicting the steam explosion load on a reactor scale, as fast running computer code. In addition, TEXAS-V code could be to evaluate the impact of various uncertainties, which are not clearly understood yet, to provide a conservative envelope for the steam explosion

  9. Quantification de la Charge Virale et tests de résistance du VIH-1 aux ARV à partir d’échantillons DBS (Dried Blood Spots chez des patients Guinéens sous traitement antirétroviral

    Directory of Open Access Journals (Sweden)

    Nestor Bangoura

    2015-05-01

    Full Text Available Problématique: Comme dans plusieurs pays du Sud, le suivi virologique des patients sous traitement antirétroviral (TARV en Guinée est timide voire inexistant dans certaines localités. Le but de cette étude était d’évaluer la faisabilité technique et logistique de l’utilisation des DBS dans les tests de charge virale (CV et de génotypage.Méthode: De septembre à octobre 2010, les DBS ont été préparés à partir de prélèvements sanguins de patients adultes sous TARV. Le délai d’envoi des échantillons au laboratoire de référence était de 30 jours maximum après le prélèvement et se faisait à température ambiante. La CV a été quantifiée et les échantillons de patients en échec virologique (CV ≥ 3 log10 copies/mL ont été génotypés selon le protocole de l’ANRS. L’algorithme de Stanford version 6.0.8 a été utilisé pour l’analyse et l’interprétation des mutations de résistance.Résultats: Parmi les 136 patients inclus, 129 et 7 étaient respectivement sous première et deuxième ligne de traitement avec une médiane de suivi de 35 mois [IQR: 6-108]. L’échec virologique a été noté chez 33 patients. Parmi eux, 84.8% (n = 28/33 ont bénéficié d’ungénotypage. Le taux de résistance global était de 14% (n = 19/136. Le CRF02_AG était le sous type viral le plus prévalent (82%; n = 23.Conclusion: En plus de montrer la faisabilité technique et logistique des tests de CV et de génotypage à partir des DBS, ces résultats montrent l’intérêt de leurs utilisations dans le suivi virologique des patients sous TARV. Cette étude a permis également de documenter l’échec virologique, la résistance aux ARV et la diversité génétique du VIH-1 en Guinée.Mots clés: VIH-1, Résistance aux ARV, DBS (Dried Blood Spots, Guinée Conakry, Génotypage,Charge Virale. Quantification of Viral load and resistance tests of HIV-1 to ARVs from dried blood spotssamples in Guinean patients undergoing

  10. Separate and integral effect tests for validation of cooling and operational performance of the APR+ passive auxiliary feedwater system

    International Nuclear Information System (INIS)

    The passive auxiliary feedwater system (PAFS) is one of the advanced safety features adopted in the APR+, which is intended to completely replace the conventional active auxiliary feedwater system. With an aim of validating the cooling and operational performance of PAFS, an experimental program is in progress at KAERI, which is composed of two kinds of tests; the separate effect test and the integral effect test. The separate effect test, PASCAL (PAFS Condensing Heat Removal Assessment Loop), is being performed to experimentally investigate the condensation heat transfer and natural convection phenomena in PAFS. A single, nearly-horizontal U-tube, whose dimensions are the same as the prototypic U-tube of the APR+ PAFS, is simulated in the PASCAL test. The PASCAL experimental result showed that the present design of PAFS satisfied the heat removal requirement for cooling down the reactor core during the anticipated accident transients. The integral effect test is in progress to confirm the operational performance of PAFS, coupled with the reactor coolant systems using the ATLAS facility. As the first integral effect test, an FLB (feedwater line break) accident was simulated for the APR+. From the integral effect test result, it could be concluded that the APR+ has the capability of coping with the hypothetical FLB accident by adopting PAFS and proper set-points of its operation.

  11. Validating the AP[R] German Language Exam through a Curricular Survey of Third-Year College Language Courses

    Science.gov (United States)

    Bischof, Deborah Lokai

    2005-01-01

    Curriculum surveys are used periodically to validate the use of Advanced Place Program[R] (AP[R]) Exams as assessments of skills required for advanced college-level study. In the case of AP German Language, the target level is third-year college language study. This article presents results from a 2003 curriculum survey completed by third-year…

  12. Development of the Phenomena Identification Ranking Table (PIRT) for the Passive Auxiliary Feedwater System (PAFS) of the APR+

    International Nuclear Information System (INIS)

    The APR+ (Advanced Power Reactor plus) is a Gen- III+ pressurized water reactor (PWR) of which the standard design is currently being developed in Korea. This reactor adopts new design features which are believed to contribute not only to enhancement in nuclear safety but also to improvement in economic competitiveness. While the conventional nuclear power plants have utilized the active cooling systems, the APR+ adopts two types of passive safety features; an advanced fluidic device (FD+) and a passive auxiliary feedwater system (PAFS). The PAFS is one of the passive cooling systems of the APR+ which can replace an active system for auxiliary feedwater injection to a steam generator. A schematic diagram of the PAFS is shown in Fig. 1. It cools down the secondary system by heat transfer at horizontal heat exchangers in a PCCT (Passive Condensation Cooling Tank). High pressure steam flow from the steam generator is condensed in the horizontal heat exchanger, and the water in the PCCT pool is evaporated by a boiling heat transfer at the outside wall of the heat exchanger. With an aim of validating the cooling and operational performance of the PAFS, a separate effect test, PASCAL (PAFS Condensing heat removal Assessment Loop) is being performed at KAERI (Korea Atomic Energy Research Institute). In this study, Phenomena Identification and Ranking Table (PIRT) has been developed for identifying the major parameters affecting the thermal-hydraulic phenomena which originate from the adoption of the PAFS in the APR+. The PIRT process can be widely used to improve a safety analysis code for a new application and to establish experimental programs and to support the resolution of the licensing issues. The PIRT process used in this study follows the methodology previously applied in the APR1400 (Advanced Power Reactor 1400 MWe) PIRTs for large break loss of coolant accident (LBLOCA) and direct vessel injection (DVI) line break events

  13. Development of the Phenomena Identification Ranking Table (PIRT) for the Passive Auxiliary Feedwater System (PAFS) of the APR+

    Energy Technology Data Exchange (ETDEWEB)

    Song, Chul Hwa; Chung, Bub Dong; Kang, Kyoung Ho; Kang, Han Ok [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Yun, Byong Jo [Pusan National University, Busan (Korea, Republic of); Bang, Young Suk [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of); Seong, Ho Je [KEPCO E and C, Yongin (Korea, Republic of); Hong, Soon Joon [FNC Technology Co. Ltd., Seoul (Korea, Republic of); Sim, Suk Ku [EN2t Inc., Daejeon (Korea, Republic of)

    2012-05-15

    The APR+ (Advanced Power Reactor plus) is a Gen- III+ pressurized water reactor (PWR) of which the standard design is currently being developed in Korea. This reactor adopts new design features which are believed to contribute not only to enhancement in nuclear safety but also to improvement in economic competitiveness. While the conventional nuclear power plants have utilized the active cooling systems, the APR+ adopts two types of passive safety features; an advanced fluidic device (FD+) and a passive auxiliary feedwater system (PAFS). The PAFS is one of the passive cooling systems of the APR+ which can replace an active system for auxiliary feedwater injection to a steam generator. A schematic diagram of the PAFS is shown in Fig. 1. It cools down the secondary system by heat transfer at horizontal heat exchangers in a PCCT (Passive Condensation Cooling Tank). High pressure steam flow from the steam generator is condensed in the horizontal heat exchanger, and the water in the PCCT pool is evaporated by a boiling heat transfer at the outside wall of the heat exchanger. With an aim of validating the cooling and operational performance of the PAFS, a separate effect test, PASCAL (PAFS Condensing heat removal Assessment Loop) is being performed at KAERI (Korea Atomic Energy Research Institute). In this study, Phenomena Identification and Ranking Table (PIRT) has been developed for identifying the major parameters affecting the thermal-hydraulic phenomena which originate from the adoption of the PAFS in the APR+. The PIRT process can be widely used to improve a safety analysis code for a new application and to establish experimental programs and to support the resolution of the licensing issues. The PIRT process used in this study follows the methodology previously applied in the APR1400 (Advanced Power Reactor 1400 MWe) PIRTs for large break loss of coolant accident (LBLOCA) and direct vessel injection (DVI) line break events

  14. Analysis of steam condensation in APR1400 IRWST for loss of coolant accident

    International Nuclear Information System (INIS)

    The In-Containment Refueling Water Storage Tank (IRWST) of APR1400 is installed at the bottom of containment building to promote the plant safety functions during an accident. This design feature brings about uncertainty factors which may necessitate conventional prediction of temperature and pressure of containment building improved or revised when an accident occurs. The hot steam which is released from RCS break enters the IRWST through four Pressure Relief Dampers (PRDs). It is expected to be condensed with water stored in IRWST, in which water is colder than incoming steam. The purpose of this study is to investigate the influence of IRWST and pressure relief damper on back pressure and temperature in APR1400 containment codes such as CONTEMPT-LT and GOTHIC. The comparison of codes showed that GOTHIC code be more appropriate for the prediction of containment pressure and temperature under the condition of steam condensation occurring in confined water pool. Especially, the GOTHIC has superior capability to treat multi-compartmentalized geometry This study developed one-compartment (single) model, two-compartment (separated) model, and three-dimension (3-D) model, respectively. Two compartment model separates the IRWST from the other containment compartments. In 3-D model, only the IRWST is nodalized with Cartesian modeling. The single model is developed for comparison with two-compartment model which can analyze PRD's influence. The separated model for predicting PRD's influence divides the space between containment and IRWST. 3-D model for IRWST was generated because it is not symmetric considering location of sparger, pump, and suction sump. Therefore, IRWST is simulated with not only detailed three-dimensional behavior but also independent flow paths for four PRDs. Many experimental studies for the direct-contact heat transfer in stratified steam water flows, cocurrent or countercurrent, have been performed (Segev et al., 1981; Lim et al., 1981; Kim and

  15. Apreçamento de opções de IDI usando o modelo CIR

    Directory of Open Access Journals (Sweden)

    José Santiago Fajardo Barbachan

    2003-06-01

    Full Text Available A opção de IDI da BM&F possui características peculiares que torna o seu apreçamento diferente das opções de taxa de juros mais comuns, como as de títulos de renda fixa. Este artigo desenvolve uma fórmula para apreçamento dessas opções de IDI, utilizando a precificação livre de arbitragem. O modelo utilizado considera apenas um fator estocástico: a taxa de juros livre de risco de curto prazo. A equação diferencial usada para modelar o comportamento da taxa de juros é a do modelo CIR (COX INGERSOLL & ROSS, 1985, que possui reversão à média e não permite a existência de taxas de juros nominais negativas. Também é feita uma estimação dos parâmetros do modelo proposto baseando-se em dados históricos, para então comparar o preço teórico da opção baseado nestes parâmetros com os preços de mercado e com o preço teórico considerando a modelagem de Vasicek (1977.The IDI option from the BM&F (Commodities and Futures Exchange has unusual characteristics, that make its pricing different from common interest rate options. This paper develops a closed form formula for the pricing of these IDI options, using an arbitrage-free pricing approach. The model used considers only one stochastic factor: the short-term risk-free interest rate. The differential equation used to model the behavior of the interest rate comes from the CIR (COX INGERSOLL & ROSS, 1985 model, which has mean reversion property and does not allow negative nominal interest rates. It is also done a parameter estimation of the proposed model based on historic data, and then compares the theoretical price of the option based on these parameters with the market price and with the theoretical price considering the Vasicek (1977 model.

  16. Numerical Analysis of Molten Corium Dispersion during Hypothetical High-Pressure Accidents in APR1400 Nuclear Power Plant

    International Nuclear Information System (INIS)

    During a hypothetical high-pressure accident in a nuclear power plant (NPP), molten corium can be ejected through a breach of a reactor pressure vessel (RPV) and dispersed by the following jet of a high pressure steam in the RPV. The dispersed corium is fragmented into smaller droplets in a reactor cavity of the NPP by the steam jet with very high velocity and is released into the upper compartment of the NPP by an overpressure in the cavity. The heat-carrying fragments of the corium transfer the thermal energy to the ambient air in the containment and react chemically with steam and generate hydrogen which may be burnt in the containment. The thermal loads from the ejected molten corium on the containment which is called direct containment heating (DCH) can threaten the integrity of the containment. New generation NPPs such as APR1400 and EPR have been designed in consideration of reducing the possibility of the containment failure from the DCH. In order for that, APR1400 has a convolute-type corium chamber connected to the reactor cavity. In the case of EPR, severe-accident dedicated depressurization valves are installed to preclude a high pressure melt ejection (HPME). DCH in a NPP containment is related to many physical phenomena such as multi-phase hydrodynamics, thermodynamics and chemical reaction. In the evaluation of the DCH load, the melt dispersion rates depending on the RPV pressure are the most important parameter. Mostly, DCH was evaluated by using lumped-analysis codes with some correlations obtained from experiments for the dispersion rates. The corium dispersion rates for many types of the NPP containments had been obtained by experiments in 90s. And some correlations from the experimental data were developed. As mentioned above, APR1400 has a corium chamber to reduce the corium dispersion rate. But there is no experimental data for the dispersion rate specific to the APR1400 cavity geometry. So its performance for capturing of the dispersed corium

  17. Facteurs prédictifs de la réponse à la CERA chez les hémodialysés chroniques naïfs de traitement par agent stimulant l’érythropoïèse

    Science.gov (United States)

    Ezziani, Mariam; Najdi, Adil; Mikou, Souad; Hanin, Hakim; Arrayhani, Mohammed; Houssaini, Tarik Sqalli

    2015-01-01

    La correction et la stabilité du taux d'hémoglobine est un objectif majeur du traitement de l'anémie chez les hémodialysés chroniques. Toutefois, la cible d'hémoglobine > 11g/dl fixée par les recommandations demeure difficile à atteindre dans notre contexte. Le but de cette étude est d’évaluer la réponse au traitement par CERA (continuous erythropoietin receptor activator) chez une population d'hémodialysés chroniques naïfs de tout traitement par agent stimulant de l’érythropoïèse et étudier les différents facteurs associés à une mauvaise réponse au traitement. Il s'agit une étude prospective mono centrique faite au sein d'une population d’ hémodialysés chroniques. Ont été inclus les patients en hémodialyse depuis plus de 12 mois, naïfs de tout traitement par agent stimulant de l’érythropoïèse (ASE) et ayant un taux d'hémoglobine(Hb) 11g/dl. Sur 87 patients en hémodialyse périodique, 22 (25,3%) sont naïfs de tout traitement par ASE. Il s'agit de 13 hommes et 9 femmes avec un âge moyen de 46 ± 19 ans et une ancienneté en hémodialyse de 67 ± 59 mois. Le taux initial d'hémoglobine est de 7,8 ± 1,3 g/dl. Au bout de 4 mois de traitement régulier par la CERA, le taux final d'Hb est de 10,9 ± 2,1g/dl et 63,6% des patients ont atteint la cible d'Hb > 11g/dl. La dose moyenne de CERA à la fin de l’étude est de 0,89 ± 0,35 µg/kg/15j. L'analyse des facteurs prédictifs montre que la réponse finale dépend du taux d'Hb initial (p = 0,002). En effet, quand le taux d'Hb initial est > 8 g/dl, le taux de réponse est de 88% vs 46% lorsque le taux d'Hb 11 g/dl sans dépasser 13 g/dl [9, 10]. Cependant, le maintien d'un taux d'hémoglobine stable nécessite du temps, des ressources humaines et financières et exige des adaptations thérapeutiques fréquentes [11]. Le méthoxy polyéthylène glycol-époétine bêta, activateur continu du récepteur de l’érythropoïétine (C.E.R.A), est un nouvel ASE qui permet la

  18. Numerical Analysis of Overpressure Transient during Cold Shutdown Operation for APR1400 Nuclear Power Plant

    International Nuclear Information System (INIS)

    ASME code describes specified requirements as allowable pressure for materials of RCPB for low temperature condition. RCPB should be protected during the condition as well because, if it fails, radioactive material can be released. ASME section III appendix G stipulates that maximum allowable pressure of reactor coolant system is 20% of hydrostatic test pressure which means the maximum allowable pressure below lowest service temperature. Generally we determine most severe mass-addition or energy-addition transients arisen by operator errors, malfunction of components or other causes for initiating events of LTOP (low temperature overpressure protection) analysis. According to safety analysis report for APR1400, most severe transient for mass addition begins from startup of one charging pump and four high pressure safety injection (HPSI) pumps at the same time and, on the other hand, most severe transient for energy addition begins from startup of one reactor coolant pump and, as a results of it, heat transfer from secondary side of SG filled with higher temperature water to primary side of SG. If RCS pressure increases and reaches a set pressure of LTOP relief valves, installed on suction pipe of shutdown cooling system (SCS), the valves perform the function of RCPB protection during cold shutdown status. PR1400 for overpressure transient under cold shutdown status. From the results of analysis of mass addition and energy addition, maximum RCS pressure is maintained lower than maximum allowable pressure for LTOP required in ASME code

  19. Numerical study on thermal stratification phenomenon in SCS branch pipe for APR1400

    International Nuclear Information System (INIS)

    The thermal stratification in the unisolable branch pipe for the Shutdown Cooling System (SCS) suction line for APR1400 has been studied. The vertical-horizontal branch pipe with an isolation valve at the end, and under Reactor System (RCS) operating condition is susceptible to the thermal stratification due to the stagnation flow around the isolation valve. The formation of the thermal stratification at the horizontal part of the branch line should be evaluated to determine the design consideration of thermal fatigue. Three dimensional transient analysis for the thermal stratification in a branch pipe is performed using the computational fluid dynamics code, FLUENT, to evaluate the velocity and temperature distribution. Parametric studies have been carried out to investigate the effect of the design and operating conditions. Parameters like the hot leg flow velocity, the outleakage through the isolation valve and the thermal insulation on piping wall are taken account. The analyses show that the temperature difference caused by the thermal stratification at the horizontal part of the unisolable branch pipe is not remarkable under normal operating conditions since the turbulent penetration length is developed deeply in the branch pipe due to the high velocity flow in the RCS hot leg. (author)

  20. A study on the mitigating capability of an auxiliary feedwater system during SBO for APR1400

    International Nuclear Information System (INIS)

    The objective of this paper is to establish an auxiliary feedwater (AFW) operational technical bases for the Korean Next Generation Reactor (APR1400) by modeling the plant, and by analyzing station blackout (SBO) using the MELCOR code. For the integrity of the reactor vessel and containment safety against severe accidents, it is essential to understand the severe accident sequences and to assess accident progression accurately using computer codes. Furthermore, it is important to attain the capability to analyze the advanced nuclear reactor design for the severe accident prevention and mitigation. Accident analyses are also undertaken to find out how effective AFW is mitigating in severe accident progresses. A nominal base case for SBO without AFW, time interval between feedwater stop and reactor vessel failure is 12,740 seconds. When AFW operates to mitigate the SBO accident progression 2, 4 and 8 hours after SBO starts, the reactor vessel failure is delayed for 20,415 seconds, 22,633 seconds and 26,508 seconds, respectively thus the operator has more time available for AC recovery and accident mitigation to prevent reactor vessel failure. (author)

  1. Numerical Analysis of Overpressure Transient during Cold Shutdown Operation for APR1400 Nuclear Power Plant

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Byung Soo; Kim, Yun Il; Jung, Ae Ju; Min, Bok Ki [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2015-05-15

    ASME code describes specified requirements as allowable pressure for materials of RCPB for low temperature condition. RCPB should be protected during the condition as well because, if it fails, radioactive material can be released. ASME section III appendix G stipulates that maximum allowable pressure of reactor coolant system is 20% of hydrostatic test pressure which means the maximum allowable pressure below lowest service temperature. Generally we determine most severe mass-addition or energy-addition transients arisen by operator errors, malfunction of components or other causes for initiating events of LTOP (low temperature overpressure protection) analysis. According to safety analysis report for APR1400, most severe transient for mass addition begins from startup of one charging pump and four high pressure safety injection (HPSI) pumps at the same time and, on the other hand, most severe transient for energy addition begins from startup of one reactor coolant pump and, as a results of it, heat transfer from secondary side of SG filled with higher temperature water to primary side of SG. If RCS pressure increases and reaches a set pressure of LTOP relief valves, installed on suction pipe of shutdown cooling system (SCS), the valves perform the function of RCPB protection during cold shutdown status. PR1400 for overpressure transient under cold shutdown status. From the results of analysis of mass addition and energy addition, maximum RCS pressure is maintained lower than maximum allowable pressure for LTOP required in ASME code.

  2. General relativistic magnetohydrodynamic simulations of binary neutron star mergers with the APR4 equation of state

    Science.gov (United States)

    Endrizzi, A.; Ciolfi, R.; Giacomazzo, B.; Kastaun, W.; Kawamura, T.

    2016-08-01

    We present new results of fully general relativistic magnetohydrodynamic simulations of binary neutron star (BNS) mergers performed with the Whisky code. All the models use a piecewise polytropic approximation of the APR4 equation of state for cold matter, together with a ‘hybrid’ part to incorporate thermal effects during the evolution. We consider both equal and unequal-mass models, with total masses such that either a supramassive NS or a black hole is formed after merger. Each model is evolved with and without a magnetic field initially confined to the stellar interior. We present the different gravitational wave (GW) signals as well as a detailed description of the matter dynamics (magnetic field evolution, ejected mass, post-merger remnant/disk properties). Our simulations provide new insights into BNS mergers, the associated GW emission and the possible connection with the engine of short gamma-ray bursts (both in the ‘standard’ and in the ‘time-reversal’ scenarios) and other electromagnetic counterparts.

  3. General Relativistic Magnetohydrodynamic Simulations of Binary Neutron Star Mergers with the APR4 Equation of State

    CERN Document Server

    Endrizzi, Andrea; Giacomazzo, Bruno; Kastaun, Wolfgang; Kawamura, Takumu

    2016-01-01

    We present new results of fully general relativistic magnetohydrodynamic (GRMHD) simulations of binary neutron star (BNS) mergers performed with the Whisky code. All the models use a piecewise polytropic approximation of the APR4 equation of state (EOS) for cold matter, together with a "hybrid" part to incorporate thermal effects during the evolution. We consider both equal and unequal-mass models, with total masses such that either a supramassive NS or a black hole (BH) is formed after merger. Each model is evolved with and without a magnetic field initially confined to the stellar interior. We present the different gravitational wave (GW) signals as well as a detailed description of the matter dynamics (magnetic field evolution, ejected mass, post-merger remnant/disk properties). Our simulations provide new insights into BNS mergers, the associated GW emission and the possible connection with the engine of short gamma-ray bursts (both in the "standard" and in the "time-reversal" scenarios) and other electro...

  4. Thermal-hydraulic evaluation of passive containment cooling system of improved APR+ during LOCAs

    Energy Technology Data Exchange (ETDEWEB)

    Jeon, Byong Guk; No, Hee Cheon [Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of)

    2014-05-15

    In performance of Passive Containment Cooling System (PCCS), sound operation of PCCS heat exchanger (HX) tubes is vital. To clarify their heat transfer function, various experiments are in progress, involving our group. Furthermore, in case of externally condensed HXs, careful evaluation of flow instability inside HX tubes are of prime importance. In PANDA integral tests targeting HXs of KERENA, a huge oscillation of flow inside tubes is observed. Flow instability is attributed to various reasons and classified into two types: static instability (ex. Ledinegg instability) and dynamic instability (ex. density wave oscillation). The former one is related to multiple stable flow rates at a given pressure drop under equilibrium condition while the latter one involves propagation time and feedback phenomena in transient condition. PCCS tubes correspond to the second type, dynamic instability. The detailed explanations are well documented. Our group suggested a PCCS design featuring an air holdup tank (AHT) for removing air near heat exchangers. Based on the design, the thermal hydraulic characteristics of PCCS are explored in this paper. Thermal hydraulic assessment of proposed PCCS is performed using a system code, MARS. Based on APR+, the required number of PCCS HX tubes are calculated with respect to AHT volume. We confirmed that larger AHT is preferred. Flow instability inside PCCS HX tubes are observed. Through sensitivity study, larger inlet orifice plate, return nozzle height, and tube angle are found to be most effective in stabilizing the flow.

  5. Numerical study of fluidic device in APR1400 using free surface model

    International Nuclear Information System (INIS)

    A fluidic device (FD) has been adopted in the safety injection tanks (SITs) of APR1400. A flow control mechanism of the FD was used to vary the flow regime in the vortex chamber corresponding to the SITs water level. The flow regime in the vortex chamber has a different pressure loss from low to high in accordance with the SITs water level. Nitrogen at the top of the SIT could be released owing to inertia of discharge flow when changing from a high flow rate to a low flow rate. This phenomenon is important to design improvement perspective because it can affect the performance of the FD. This paper shows a result of a preliminary numerical study to obtain the transient data related to air release in the flow turn down period using a two fluid free surface model provided from ANSYS CFX 13.0. In conclusion, there is no significant effect on the performance of the FD, though a small quantity of air is released during the flow turn down period

  6. Ārsta un farmaceita sadarbība pacientu aprūpē

    OpenAIRE

    Tione, Zane

    2016-01-01

    Sakārtota un pieejama veselības aprūpes sistēma valstī, var ievērojami uzlabot dzīves kvalitāti un nodrošināt valsts izaugsmi un konkurētspēju. Tomēr, kā zināms, svarīgs nosacījums šajā procesā ir arī pašu sistēmas dalībnieku iniciatīvai, viņu izrādītā vēlme uz sadarbību, vienotu mērķu sasniegšanai. Aktuāli ir noskaidrot kāda ir šī brīža situācija valstī, vai ārstiem un farmaceitiem ir vēlme šo komunikāciju uzlabot. Bakalaura darba mērķis ir noskaidrot vai pastāv ārstu un farmaceitu sadarbīb...

  7. Development of combined modularization technology for APR+ (Advanced Power Reactor) in Korea

    International Nuclear Information System (INIS)

    Full text: KHNP is currently operating 20 nuclear power plants and constructing 8 units in Korea. With the accumulated experience of operation and construction of NPPs over the past 50 years, KHNP tries to develop the original nuclear power reactor (APR+). The R and D project for 'combined modularization', which is a part of APR+ common core technology development, is being carried out and will be implemented by July 2010. This R and D project was initiated from the feasibility study on the modularization of structure and system facility for NPPs (2002). On the basis of the feasibility study result, The SC (Steel plate Concrete) structure technology development had been performed from 2005 to 2008, and the SC structure technology is under audit by the regulatory institution prior to the application for nuclear construction project. The research of combined modularization is an extension from the SC structure technology development. The research is divided into three phases. During first phase, by July 2010, the applicability of SC structure enlargement will be reviewed and conceptual design of combined/equipment modularization will be performed. In second phase, the basic design and construction feasibility evaluation of the screened combined/equipment modularization will be completed within July 2013. Afterward, in the final phase, optimized modularization technique will be realized through technical supplementation by Dec. 2015. Two main objectives will be achieved in the first phase study. The first one is to obtain design reliabilities for the SC structure by evaluating its applicability in auxiliary/compound building. The other one is to establish modularization requirements for design, procurement, manufacture and installation. To ensure these objectives, the flow sheet of technology development is greatly divided into 5 steps as follows. First step is to establish the screen criteria for adopting modularization. It's possible to catch the attitude of impact

  8. Sub compartment pressurization analysis for auxiliary building of APR1400DC

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Moon Oh; Lee, Hee Do [Atomic Creative Technology, Daejeon (Korea, Republic of)

    2012-10-15

    Generally, the sub compartment of PWR means a fully or partially enclosed volume that could house high-energy piping systems or restrict the flow of fluid in the event of a postulated pipe rupture. To meet the requirements of General Design Criteria (GDC) 4 and 50, Standard Review Plan (SRP) 6.2.1.2 states that the sub compartments shall be designed with sufficient margin to prevent the fracture of structure due to pressure differential across the walls of the sub- compartment and specifies the criteria related to the design and functional sub compartment nodalization schemes, vent flow path and vent flow behavior. Therefore the sub compartments structures within the containment and auxiliary building are designed to withstand the transient differential pressures loads, jet impingement forces, and pipe whip forces occurring due to a postulated pipe break. In this paper, the analyses of pressure transients after a postulated pipe rupture in sub compartments of APR1400DC auxiliary building is performed and the calculated peak differential pressures during the piping break transients for each sub compartment are less than structural design differential pressures.

  9. Evaluation on thermal-hydraulic characteristics for passive safety device of APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Yoo, Seong Yeon; Lee, S. H.; Son, M. K. [Korea Association for Nuclear Technology, Taejon (Korea, Republic of); Jee, M. S.; Chung, M. H. [Chungnam National Univ., Taejon (Korea, Republic of)

    2001-07-15

    To establish evaluation and verification guideline for the APR1400, thermal-hydraulic characteristics for fuel rod bundle, reactor vessel and fluidic device is analyzed using FLUENT. Scope and major results of research are as follows : Thermal-hydraulic characteristics for nuclear fuel rod bundle: design data for nuclear fuel rod bundle and structure are surveyed, and 3 x 3 sub-channel model is adopted to investigate the fluid flow and heat transfer characteristics in fuel rod bundle. Computational results are compared with the heat transfer data measured by naphthalene sublimation method, and numerical analysis and evaluation are performed at various design conditions and flow conditions. Thermal-hydraulic characteristics for reactor vessel: reactor vessel design data are surveyed to develop numerical model. Porous media model is applied for fuel rod bundle, and full-scale, three dimensional simulation is performed at actual operating conditions. Distributions of velocity, pressure and temperature are discussed. Flow characteristics for fluidic device: three dimensional numerical model for fluidic device is developed, and numerical results are compared with experimental data obtained at KAERI in order to verify numerical simulation. In addition, variation of flow rate is investigated at various elapsed times after valve operating, and flow characteristics is analyzed at low and high flow rate conditions, respectively.

  10. Analysis of Condensation Phenomena in PAFS (Passive Auxiliary Feedwater System) Horizontal Heat Exchanger of APR+

    International Nuclear Information System (INIS)

    APR+ (Advanced Power Reactor Plus) is the next generation nuclear power plant in Korea. It adopts PAFS (Passive Auxiliary Feedwater System) on the secondary system. It can replace the conventional active system for auxiliary feedwater injection to the steam generator, and it enable to supply the coolant by a passive system. It cools down the secondary system by heat transfer at a horizontal U-tube in PCCT (Passive Condensate Cooling Tank). High pressure steam flow from the steam generator is condensed in the horizontal heat exchanger. The water in PCCT is maintained at an atmospheric pressure, so that boiling heat transfer at the outside wall of heat exchanger and natural convection occur in PCCT pool. The heat exchanger and PCCT is higher than steam generator, so condensate can be drained and injected to feedwater system without any active system. This study aims at design of the horizontal heat exchanger in PAFS. It should remove the heat generated in the steam generator. To satisfy this requirement, a system code analysis is conducted. The amount of condensation heat transfer is investigated by MARS (Multi-dimensional Analysis for Reactor Safety) code analysis

  11. Experimental program for validation of cooling and operational performance of the APR+ Passive auxiliary feedwater system

    International Nuclear Information System (INIS)

    PAFS (Passive Auxiliary Feedwater System) is one of the advanced passive safety systems adopted in the APR+ (Advanced Power Reactor plus), which is intended to completely replace the conventional active auxiliary feedwater system. PAFS cools down the steam generator's secondary side, and eventually removes the decay heat from the reactor core by introducing a natural driving force mechanism; i.e., condensing steam in nearly horizontal U-tubes submerged inside the passive condensation cooling tank (PCCT). With an aim of validating the cooling and operational performance of the PAFS, an experimental program is in progress at KAERI (Korea Atomic Energy Research Institute), which is composed of two kinds of tests; the separate effect test and the integral effect test. The separate effect test, PASCAL (PAFS Condensing Heat Removal Assessment Loop), is in progress to experimentally investigate the condensation heat transfer and natural convection phenomena in PAFS. The integral effect test is being performed to confirm the operational performance of the PAFS coupled with the other reactor coolant systems (RCS) using the thermal hydraulic integral effect test facility, ATLAS (Advanced Thermal hydraulic test Loop for Accident Simulation). This paper summarizes the up to date experimental results of the separate effect test and the integral effect test for PAFS from a cooling and operational performance point of view

  12. Preliminary Performance Analysis on APR+ PAFS Using RELAP5 and MARS Codes

    International Nuclear Information System (INIS)

    International nuclear industry has been adopting a passive safety system to enhance safety and reliability of nuclear power plant with advanced technology. Domestic industry has been also developing a specific advanced reactor, so-called advanced power reactor plus (APR+), with passive auxiliary feedwater system (PAFS). The PAFS was introduced to replace an active auxiliary feedwater system (AFWS) completely. The system function is to remove the residual heat in the primary system like the AFWS does when the main feedwater system is unavailable. PAFS consists of a passive condensate cooling tank (PCCT), a heat exchanger, valves, and pipes as shown in Fig. 1. When PAFS works, steam from steam generator is supplied and condensed into water in the heat exchange. And the water falls down by gravity and returns to the steam generator. This progress goes on repeatedly and it makes natural circulation possible in the system. The circulating flow removes continuously the primary residual heat without any active components. The performance of PAFS depends on various thermo-hydraulic (TH) phenomena occurred in the system. So understanding these phenomena is required to analyze its performance with TH code such as RELAP5 or MARS which is a regulatory audit code. Licensee in the domestic industry has been conducting the performance analysis of the PAFS with RELAP5. So the analysis of MARS model with the same input was carried out and difference between two codes was compared in this study

  13. A Framework to Measure Operator's Workload in Main Control Room of APR1400

    International Nuclear Information System (INIS)

    Though the work of operators has been changed a great deal, due to a lack of appropriate guidelines on the role allocation or communication method of operators, the problem of a lopsided workload for each operator has been raised. Thus, it is necessary to enhance the operation capability by developing the guidelines on the role definition and communication of operators in the advanced MCR of NPPs. To resolve this problem, however, a method of measuring the workload according to work execution of operators is necessary, but the applicable method is not available at this time. The objective of this research is to develop an analytical framework to evaluate the workload according to the work execution of power plant operators. A framework to measure the workload of crews in an advanced main control room has been suggested. In this research, we proposed a framework to measure and evaluate the workload of operators in an advanced MCR and the workload was measured through the simulator training experiment of the MCR of an APR1400. On the basis of these observations, it is necessary to reestablish the role and communication method of MCR operators suitable to the new operational environment and changed work and develops the appropriate operating guidelines

  14. Sensitivity Analysis of Ex-Vessel Steam Explosion usion TEXAS-V code for APR1400

    International Nuclear Information System (INIS)

    This study conducted the influence of melt velocity and melt diameter on the steam explosion calculation. There was strong influence of the jet diameter and velocity on the explosion. If there is the maximum pressure at the walls, the steam explosion loads can be too high to resist on the cavity wall. In the future study, TEXAS-V code will be used to evaluate the impact of various uncertainties to provide a conservative envelope for the steam explosion. In severe accidents, the corium can come into contact with coolant either when it flows to the bottom of the reactor vessel and encounters the reactor coolant, or when it breaches the reactor vessel and flows into the reactor containment. A steam explosion could then weaken the containment structures, such as the reactor vessel or the concrete walls of the containment building. The purpose of this study is to calculate using TEXAS-V code for ex-vessel steam explosion for a flooded reactor cavity of APR1400. TEXAS-V code to analyze and predict the ex-vessel steam explosion for a reactor scale is used

  15. Preliminary Performance Analysis on APR+ PAFS Using RELAP5 and MARS Codes

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Kyung Jin; Hong, Soon Joon [FNC Tech., SNU, Seoul (Korea, Republic of); Park, Ju Yeop; Seul, Kwang Won [KINS, Daejeon (Korea, Republic of)

    2010-10-15

    International nuclear industry has been adopting a passive safety system to enhance safety and reliability of nuclear power plant with advanced technology. Domestic industry has been also developing a specific advanced reactor, so-called advanced power reactor plus (APR+), with passive auxiliary feedwater system (PAFS). The PAFS was introduced to replace an active auxiliary feedwater system (AFWS) completely. The system function is to remove the residual heat in the primary system like the AFWS does when the main feedwater system is unavailable. PAFS consists of a passive condensate cooling tank (PCCT), a heat exchanger, valves, and pipes as shown in Fig. 1. When PAFS works, steam from steam generator is supplied and condensed into water in the heat exchange. And the water falls down by gravity and returns to the steam generator. This progress goes on repeatedly and it makes natural circulation possible in the system. The circulating flow removes continuously the primary residual heat without any active components. The performance of PAFS depends on various thermo-hydraulic (TH) phenomena occurred in the system. So understanding these phenomena is required to analyze its performance with TH code such as RELAP5 or MARS which is a regulatory audit code. Licensee in the domestic industry has been conducting the performance analysis of the PAFS with RELAP5. So the analysis of MARS model with the same input was carried out and difference between two codes was compared in this study

  16. Analysis of Condensation Phenomena in PAFS (Passive Auxiliary Feedwater System) Horizontal Heat Exchanger of APR+

    Energy Technology Data Exchange (ETDEWEB)

    Bae, Byoung Uhn; Yun, Byong Jo; Bae, Sung Won; Choi, Ki Yong; Song, Chul Hwa [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Cheon, Jong [Korea Hydro and Nuclear Power Co., Daejeon (Korea, Republic of)

    2009-10-15

    APR+ (Advanced Power Reactor Plus) is the next generation nuclear power plant in Korea. It adopts PAFS (Passive Auxiliary Feedwater System) on the secondary system. It can replace the conventional active system for auxiliary feedwater injection to the steam generator, and it enable to supply the coolant by a passive system. It cools down the secondary system by heat transfer at a horizontal U-tube in PCCT (Passive Condensate Cooling Tank). High pressure steam flow from the steam generator is condensed in the horizontal heat exchanger. The water in PCCT is maintained at an atmospheric pressure, so that boiling heat transfer at the outside wall of heat exchanger and natural convection occur in PCCT pool. The heat exchanger and PCCT is higher than steam generator, so condensate can be drained and injected to feedwater system without any active system. This study aims at design of the horizontal heat exchanger in PAFS. It should remove the heat generated in the steam generator. To satisfy this requirement, a system code analysis is conducted. The amount of condensation heat transfer is investigated by MARS (Multi-dimensional Analysis for Reactor Safety) code analysis.

  17. Traitement des diagraphies acoustiques. Deuxième partie : séparation des ondes en diagraphie acoustique Full-Waveform Acoustic Data Processing. Second Part: Wave Separation in Acoustic Well Logging

    Directory of Open Access Journals (Sweden)

    Gavin P.

    2006-11-01

    Full Text Available L'utilisation d'outils acoustiques à émetteurs-récepteurs multiples et enregistrement numérique permet de faire une microsismique de puits en utilisant des techniques de traitement dérivées du traitement sismique. Comme les enregistrements acoustiques sont composés de différents types d'ondes (ondes de volume réfractées ou réfléchies et ondes d'interface, une étape importante du traitement acoustique est la séparation des ondes. Cet article montre que la séparation des ondes peut être optimisée en fonction du choix du type de collection des enregistrements acoustiques et de la performance des algorithmes utilisés, dépendante du nombre de traces par collection. Les différents types de collection sont la collection émetteur ou récepteur commun et la collection à déport constant. Trois exemples de traitement de diagraphie acoustique sont présentés. Le premier exemple montre que les interférences des ondes qui conduisent à des anomalies sur l'estimation des logs acoustiques tels que le log de lenteur (Delta t sont réduites après une bonne séparation des ondes. Le deuxième exemple est un exemple d'imagerie en puits vertical. Le traitement par filtrage de Wiener sur une section à déport constant permet de différencier les modes réfractés et d'interface des diffractions profondes (environ 4 m créées par la présence d'intercalations dolomitiques en milieu argileux. Le troisième exemple est un exemple d'imagerie en puits horizontal. Le traitement est réalisé sur une collection point de tir commun. La combinaison de filtrage en vitesse apparente pour extraire les différents types d'ondes et de filtrage matriciel pour améliorer le rapport signal sur bruit a permis d'extraire un jeu de réflexions. La connaissance a priori de la zone réservoir a permis d'identifier les événements réfléchis en-dessous et en-dessus du drain. Cet exemple montre la nécessité d'utiliser des techniques spécifiques pour lever l

  18. Organizacijos aprūpinimo darbuotojais veiklų gerinimas gamybinės įmonės pavyzdžiu

    OpenAIRE

    Varnaitė, Evelina

    2008-01-01

    Darbas sudarytas iš trijų dalių. Pirmoje dalyje analizuojama Lietuvos ir užsienio mokslininkų suformuluota organizacijos aprūpinimo darbuotojais veiklų samprata, turinys, metodai, subjektai bei veiksniai, įtakojantys šias veiklas. Antrojoje dalyje pateikiami ir analizuojami tyrimo metu surinkti duomenys apie gamybinėje įmonėje atliekamas aprūpinimo darbuotojais veiklas. Analizė leido padaryti išvadą, kad įmonėje atliekamos aprūpinimo darbuotojais veiklos turi trūkumų. Todėl trečioje dalyje yr...

  19. Organizacijos aprūpinimu personalu veiklų tobulinimas ŽŪB „Nematekas“ pavyzdžiu

    OpenAIRE

    Matelytė, Giedrė

    2013-01-01

    Baigiamojo darbo tikslas – atlikti ŽŪB „Nematekas“ aprūpinimo personalu veiklų analizę ir pateikti projektinius sprendimus darbuotojų planavimo, verbavimo, atrankos ir adaptavimo procesams. Baigiamajame darbe atlikta personalo veiklų sampratos teorinė analizė. Atliekama personalo valdymo informacinio aprūpinimo veiklų, organizacijos aprūpinimo darbuotojais ir darbuotojų efektyvaus panaudojimo ir išlaikymo veiklų analizė. Analitinė darbo dalyje naudojami keturi tyrimo metodai: mokslinės litera...

  20. Single port-assisted fully laparoscopic abdominoperineal resection (APR) with immediate V-RAM flap reconstruction of the perineal defect.

    LENUS (Irish Health Repository)

    Ali, Sayid

    2012-09-01

    Abdominoperineal resection (APR) of anorectal cancers after neoadjuvant chemoradiotherapy may incur significant perineal morbidity. While vertical rectus abdominis muscle (V-RAM) flaps can fill the pelvic resection space with health tissue, their use has previously been described predominantly in association with laparotomy. Here, we describe a means of combination laparoscopic APR with V-RAM flap reconstruction that allows structural preservation of the entire abdominal wall throughout the oncological resection and of the deep parietal layers after V-RAM donation. Furthermore, a single port access device used at the end colostomy site allows a second senior surgeon assist with an additional two working instruments for the purpose of improved pelvic tissue retraction, especially useful in obese patients.

  1. Pharmacokinetic and pharmaco-technological approaches of actinides decorporation by an in vivo sequestering agent. Application to the development of new treatments; Approches pharmacocinetique et pharmacotechnique de la decorporation d'actinides par un agent complexant in vivo. Application a la mise au point de nouveaux traitements

    Energy Technology Data Exchange (ETDEWEB)

    Phan, G.

    2005-05-24

    modulate the pharmacokinetic parameters by prolonging their circulation time. Stealth liposomes of diameters reduced to around 100 nm (SL-100 nm) displayed a more convenient distribution which may improve the pharmacological effect of DTPA. Indeed, the administration of a single dose of approximately 3 {mu}mol.kg{sup -1} of DTPA encapsulated in SL-100 nm induced an excretion of more than 90% of the Pu injected activity after 16 days while one free DTPA dose of 30 {mu}mol.kg{sup -1} induced only less than 50% of excretion of Pu under the same conditions. Moreover, one weekly administration of the SL-100 nm makes it possible to reduce significantly the retention of plutonium in the liver to less than 2% of Pu injected activity and that in the skeleton to less than 0.2%, only 30 days after Pu contamination. All these improvements may be attributed to the increase in the aria under the curve of the DTPA concentrations (AUC) and to an increased distribution of DTPA to the liver and the skeleton by the SL-100 nm. Contrary to the injection of free DTPA, SL-100 nm liposomes seem to be able to interact with the macrophages and the hepatocytes in the liver, then to intercept plutonium and to prevent the deposition of the actinide in the skeleton in the rats. Liposomal formulations of DTPA and their pharmacokinetic studies thus make it possible to optimize the treatment of decorporation of Pu. (author) [French] Apres contamination interne par les actinides transuraniens, l'acide diethylene-triamine-pentaacetique (DTPA) est le seul traitement disponible pour accelerer la decorporation c'est-a-dire l'excretion hors de l'organisme de ces radiocontaminants par les voies naturelles (urinaire et fecale). Cependant, l'efficacite du DTPA est variable et semble limitee pour mobiliser les toxiques a partir de leurs sites de dEpot et de retention qui sont principalement le foie et le squelette. La molecule presente en effet une pharmacocinetique defavorable (faible

  2. Scoping Test on the Effects of Boron and Buffer in the Mockup PLUS7 Fuel Assembly of the APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Suh, Jeong Kwan; Kwon, Sun Guk; Kim, Jae Won; Lee, Jae Yong [KHNP Central Research Institute, Daejeon (Korea, Republic of)

    2013-10-15

    Test results of the repeatability and the boron/buffer effects are presented, and compared with the acceptance basis for the LTCC of the APR1400. To address GSI-191 of the APR1400, we have performed a series of FA tests using a mockup PLUS7. The test results of repeatability performed at limiting conditions meet the acceptance basis compared with the reference results (SK34-61∼64) within 7% difference. Boron and buffer in the fluid lowered pressure drop across the entire FA compared with the condition without them. The test results of boron and buffer effects meet the acceptance head loss (91.8 kPa) of the APR1400 with a sufficient margin. To address U. S. Nuclear Regulatory Commission (NRC) Generic Safety Issue (GSI)-191, we have performed a series of fuel assembly (FA) head loss tests. The goal of this test is to confirm that there is sufficient available head when the debris reaches the core inlets of the APR1400 during a loss-of-coolant accident (LOCA), and that the long-term core cooling (LTCC) is not impeded. To move forward with the resolution of GSI-191 in-vessel effects, we have performed a scoping test on the effects of boron and buffer at ambient temperature. In test SK34-205, repeatability of the tests was confirmed at the limiting conditions. In a scoping test SK34-245, boron and Tri-Sodium Phosphate (TSP) buffer were added prior to the debris addition.

  3. Developing Optimal Procedure of Emergency Outside Cooling Water Injection for APR1400 Extended SBO Scenario Using MARS Code

    International Nuclear Information System (INIS)

    In this study, we examined optimum operator actions to mitigate extended SBO using MARS code. Particularly, this paper focuses on analyzing outside core cooling water injection scenario, and aimed to develop optimal extended SBO procedure. Supplying outside emergency cooling water is the key feature of flexible strategy in extended SBO situation. An optimum strategy to maintain core cooling is developed for typical extended SBO. MARS APR1400 best estimate model was used to find optimal procedure. Also RCP seal leakage effect was considered importantly. Recent Fukushima accident shows the importance of mitigation capability against extended SBO scenarios. In Korea, all nuclear power plants incorporated various measures against Fukushima-like events. For APR1400 NPP, outside connectors are installed to inject cooling water using fire trucks or portable pumps. Using these connectors, outside cooling water can be provided to reactor, steam generators (SG), containment spray system, and spent fuel pool. In U. S., similar approach is chosen to provide a diverse and flexible means to prevent fuel damage (core and SFP) in external event conditions resulting in extended loss of AC power and loss of ultimate heat sink. Hence, hardware necessary to cope with extended SBO is already available for APR1400. However, considering the complex and stressful condition encountered by operators during extended SBO, it is important to develop guidelines/procedures to best cope with the event

  4. Evaluation of the APR+ Passive Auxiliary Feedwater System Performance during Main Feedwater Line Break Accident using MARS-KS

    International Nuclear Information System (INIS)

    Ever since the Nuclear Power Plant (NPP) started commercial operation, advanced NPPs have been developed to enhance performance and safety as well as the economics of the plant. As a part of a regulatory safety research of the advanced nuclear reactors, MARS-KS regulatory safety analysis code has been selected to evaluate the performance of the Passive Auxiliary Feedwater System (PAFS) during Main Feedwater Line Break (MFLB) accident of the APR+ (Advanced Power Reactor+) which is under development by Korea Hydro and Nuclear Power (KHNP). The results of the APR+ MFLB analysis and the performance of the PAFS are presented herein. MATS-KS MFLB analysis shows that the MARS-KS code well simulates dynamic thermal hydraulic behavior of the MFLB and maximum RCS pressure satisfies the acceptance criteria of 120% design RCS pressure for the MFLB accident. APR+ PAFS effectively removes the core decay heat by the natural circulation during the MFLB accidents, however, comprehensive performance of the PAFS should be evaluated against the design basis of 8 hours core heat removal until the conditions for the initiation of the Shutdown Cooling System (350 .deg. F and 400 psia) are met

  5. Evaluation of the APR+ Passive Auxiliary Feedwater System Performance during Main Feedwater Line Break Accident using MARS-KS

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, Minjeong; Ralph, Marigomena; Sim, S. K. [Environment and Energy Technology, Inc., Daejeon (Korea, Republic of); Bang, Youngseok [KINS, Daejeon (Korea, Republic of)

    2013-05-15

    Ever since the Nuclear Power Plant (NPP) started commercial operation, advanced NPPs have been developed to enhance performance and safety as well as the economics of the plant. As a part of a regulatory safety research of the advanced nuclear reactors, MARS-KS regulatory safety analysis code has been selected to evaluate the performance of the Passive Auxiliary Feedwater System (PAFS) during Main Feedwater Line Break (MFLB) accident of the APR+ (Advanced Power Reactor+) which is under development by Korea Hydro and Nuclear Power (KHNP). The results of the APR+ MFLB analysis and the performance of the PAFS are presented herein. MATS-KS MFLB analysis shows that the MARS-KS code well simulates dynamic thermal hydraulic behavior of the MFLB and maximum RCS pressure satisfies the acceptance criteria of 120% design RCS pressure for the MFLB accident. APR+ PAFS effectively removes the core decay heat by the natural circulation during the MFLB accidents, however, comprehensive performance of the PAFS should be evaluated against the design basis of 8 hours core heat removal until the conditions for the initiation of the Shutdown Cooling System (350 .deg. F and 400 psia) are met.

  6. Solvent purification using a current of water vapour. A continuous process applicable to chemical plants treating irradiated fuels; Purification des solvants par entrainement a la vapeur d'eau. Procede continu applicable aux usines chimiques de traitement des combustibles irradies

    Energy Technology Data Exchange (ETDEWEB)

    Auchapt, P.R.; Sautray, R.R.; Girard, B.R. [Commissariat a l' Energie Atomique, Centre de Production de Plutonium, Marcoule (France). Centre d' Etudes Nucleaires

    1964-07-01

    sur la decontamination. L'activite en zirconium-niobium apres traitement est indecelable et il est facile d'obtenir des facteurs de decontamination de 300 sur le ruthenium. La presence d'uranium favorise la decontamination. Pour terminer, le lecteur trouvera des considerations extra-techniques et en particulier l'ordre de grandeur des prix de revient du litre de solvant traite. (auteurs)

  7. Drop size measurements and entrainment in APR1400 during LBLOCA reflood phase

    International Nuclear Information System (INIS)

    A study has been performed to investigate droplet size in the nuclear reactor of APR1400 during LBLOCA reflood phase and to develop droplet entrainment and deposition models for SPACE (Safety and Performance CodE) which is a safety analysis tool for PWR being developed in Korea. A freezing technique for measuring the size of droplets was developed to obtain the droplet size distribution in horizontal annular flow in a pipe with a 37.1 mm diameter. Droplets are frozen by using an extremely low temperature nitrogen gas with liquid film extraction. They are then photographed with a microscope and a CCD camera and measured by means of an image process. The results are compared with various experimental data. The droplet sizes measured by the freezing technique are comparable with those measured by other methods at a high superficial air velocity (of 50 m/s). However, because of the film extraction problem, the droplet sizes measured at a low superficial air velocity of less than 40 m/s are higher than those measured by other methods. A present method suggested for predicting the Sauter mean diameter is based on the maximum droplet size correlation for the experimental data, with and without liquid film extraction. The average droplet size is remarkably smaller downstream of the liquid film extractor because large droplets from the liquid film are excluded. In order to understand and to predict a heat transfer between superheated steam and droplets properly during reflood phase of LBLOCA, it is very important to measure broken droplet sizes by spacer grids. A study, therefore, has been performed to investigate droplet size in rod bundles with spacer grids and to develop a spacer grid droplet breakup model for safety analysis codes. Experiments were conducted with liquid droplets (SMD of 300∼700 μm) and various spacer grids at superficial air velocity of 10 m/s and 20 m/s based on FLECHT SEASET. The test channel and the grids were heated to 150 .deg. C to prevent

  8. Review on the NEI Methodology of Debris Transport Analysis in Sump Blockage Issue for APR1400

    International Nuclear Information System (INIS)

    Since USNRC (United State Nuclear Regulatory Committee) initially addressed post-accident sump performance under Unresolved Safety Issue USI A-43, sump blockage issue has gone through GSI-191, Regulation Guide 1.82, Rev. 3 (RG. 1.82 Rev.3), and generic Letter 2004-02 for PWRs (Pressurized Water Reactors). As a response of these USNRC's activities, NEI 04-07 was issued in order to evaluate the post-accident performance of a plant's recirculation sump. The baseline methodology of NEI 04-07 is composed of break selection, debris generation, latent debris, debris transport, and head loss. In analytical refinement of NEI 04-07, computational fluid dynamic (CFD) is suggested for the evaluation of debris transport in emergency core cooling (ECC) recirculation mode as guided by RG. 1.82 Rev.3. In Korea nuclear industry also keeps step with international activities of this safety issue, with Kori 1 plant as a pioneering edge. Korean nuclear industry has been also pursuing development of an advanced PWR of APR1400, which incorporates several improved safety features. One of the key features, considering sump blockage issue, is the adoption of IRWST (In-containment Refueling Water Storage Tank). This device, as the acronym implies, changes the emergency core cooling water injection pattern. This fact makes us to review the applicability of NEI 04-07's methodology. In this paper we discuss the applicability of NEI 04- 07's methodology, and more over, new methodology is proposed. And finally the preliminary debris transport is analyzed

  9. Steady state flow evaluations for passive auxiliary feedwater system of APR

    International Nuclear Information System (INIS)

    This paper briefly introduces a methodology to evaluate steady state flow of APR+ Passive Auxiliary Feedwater System (PAFS). The PAFS is being developed as a safety grade passive system to completely replace the existing active Auxiliary Feedwater System (AFWS). Natural circulation cooling can be generally classified into the single-phase, two-phase, and boiling-condensation modes. The PAF is designed to be operated in a boiling-condensation natural circulation mode. The steady-state flow rate should be equal to the steady-state boiling/condensation rate determined by the steady-state energy and momentum balances in the PAFS. The determined steady-state flow rate can be used in the design optimization for the natural circulation loop of the PAFS through the steady-state momentum balance. Since the retarding force, which is to be balanced by the driving force in the natural circulation system design depends on the reliable evaluation of the success of a natural circulation system design depends on the reliable evaluation of the pressure loss coefficients. In PAFS, the core decay heat is released by natural circulation flow between the S G secondary side and the Passive Condensation Heat Exchanger (PCHX) that is immersed in the Passive Condensation Cooling Tank (PCCT). The PCCT is located on the top of Auxiliary building The driving force is determined by the difference between the S/G (heat Source) secondary water level and condensation liquid (heat sink) level. It will overcome retarding force at flowrate in the system, which is determined by vaporization and condensation of the steam which is generated at the S/G by the latent heat in system. In this study, the theoretical method to estimate the steady state flow rate in boiling-condensation natural circulation system is developed and compared with test results

  10. Integral experiment and RELAP5 analysis for DVI line break SBLOCA in APR1400

    International Nuclear Information System (INIS)

    The thermal-hydraulic phenomena of Direct Vessel Injection (DVI) line Small-Break Loss-of-Coolant Accident (SBLOCA) in the pressurized water reactor, APR1400, were investigated. To understand the thermal-hydraulic phenomena during the SBLOCA transient, the reduced-height and reduced-pressure integral test loop, SNUF (Seoul National University Facility), was constructed according to the energy scaling methodology. The methodology conserves the mass inventory and energy of the system in the same time scale as the prototype. From the RELAP5 analysis, the energy scaling methodology was confirmed to show the reasonable transient when ideally scaled-down SNUF model was compared to the prototype model. In order to overcome the limitation of power in actual SNUF, the modified-power curve was utilized without simulating the forced flow by pump, so that those corrections did not affect the major phenomena during transient. Geometric distortion of actual SNUF also did not strongly disturb the thermal-hydraulic behaviors, especially occurrence of the downcomer seal clearing. In the experiments according to the conditions determined by energy scaling methodology, the phenomenon of downcomer seal clearing had a dominant role in decrease of the system pressure and increase of the coolant level of core. It occurred when the steam injected from cold legs penetrated the coolant in upper downcomer toward the broken DVI line. The experimental results was used to validate the calculation capability of RELAP5, especially for the downcomer seal clearing phenomenon, and to estimate the scale-up capability of RELAP5 code according to the scaling methodology. (authors)

  11. Analysis of severe accident progression for in-vessel corium retention estimation in the APR 1400

    International Nuclear Information System (INIS)

    The scope and content of this technical report is to evaluate high-pressure transients of total Loss of Feed Water (LOFW) to the steam generators and Station Blackout (SBO), and low-pressure transients of Loss of Coolant Accident (LOCA) without Safety Injection (SI) using the SCDAP/RELAP5/MOD3.3 computer code from transient initiation to reactor vessel failure in the APR 1400. The SCDAP/RELAP5/MOD3.3 results have shown that the pressurizer surge line had failed before reactor vessel failure, which results in a rapid decrease of RCS pressure in the high-pressure sequences of the LOFW and the SBO transients. The LOFW with intentional RCS depressurization using the safety depressurization system prevents failure of the pressurizer surge line and results in actuation of the safety injection tanks. A large mass of the melted and relocated core material in the bottom of core region at approximately 6 hours was relocated to the lower plenum of the reactor vessel in the 2-inch and the 3-inch SBLOCAs, which results in the reactor vessel failure by creep. In the SBLOCA sequence without the safety injection, the actuation of the SITs can be possible for the operator to have time of 4-5 hours in the action of the severe accident mitigation strategy to prevent reactor vessel failure. In all sequences, approximately 50-90 % of the core material was melted and relocated to the lower plenum of the reactor vessel at the time of reactor vessel failure and approximately 30-60 % of the fuel rod cladding was oxidized

  12. Experiment and RELAP5 analysis for the downcomer boiling of APR1400 under LBLOCA

    International Nuclear Information System (INIS)

    Experiment has been carried out to investigate the boiling phenomena in the downcomer and RELAP5/MOD3.2 has been assessed with the present experimental data. The heated wall with a thickness of 8.2 cm and a height of 27 cm is used, which is made of the same material as the prototype (APR1400) with chrome coating against rusting. From the experiment, we visually observed strong liquid recirculation and vapor jetting near the heated wall due to the axial migration of voids only in the thin layer of the heated wall but little bubble migration to the bulk region. The size of the thin layer is about 4 cm, which is used for the determination of the radial nodal size in the radial double-node schemes. The RELAP5 calculations using three different nodal schemes are compared with experimental data in aspects of water level, void fraction, wall temperatures and phase velocities. The radial single-node scheme produces no liquid recirculation, resulting in the sudden level drop due to a sudden increase in void fraction. The double-nodal scheme with the top-bottom radial connections yields the strong circulation, eliminating the sudden level drop. As a result, the scheme produces better results than the radial single-nodal scheme and the double-nodal scheme with all radial connections. Based on the information from the measurement of local liquid velocity profile and visual observation, the drift velocity model is developed to apply into the downcomer with a large gap and a vertical heated wall. The proposed drift velocity model has been implemented into RELAP5 and verified with the experimental results. (author)

  13. Traitement du Cupus érythémateux systémique avec atteinte réivaCe et/ou neuropsychiatrique

    OpenAIRE

    Belgaid, Ahlam; Benasid, Imène; Benbachir, Khadidja

    2013-01-01

    Le lupus érythémateux systémique est l'archéytpe des maladies auto-immunes, d'étiopathogénie complexe, de symptomatologie variable, évoluant par poussées entrecoupées de phases de rémission et touchant avec prédilection la jeune population féminine. En raison de sa fréquence et de sa gravité, l'atteinte rénale est une des manifestations majeures de la maladie lupique dont le diagnostic et le traitement précoce conditionnent le pronostic. D'autre part l'atteinte neuropsychiat...

  14. Procédé intégré de traitement du gaz naturel Integrated Process for Natural Gas Treatment

    OpenAIRE

    Larue J.; Lebas E.

    2006-01-01

    L'Institut français du pétrole a développé une nouvelle technique de traitement du gaz naturel, le procédé intégré IFPEXOL, basé sur une nouvelle mise en oeuvre de méthanol à basse température, qui incorpore dans un procédé unique les trois fonctions de déshydratation, extraction des liquides de gaz naturel (LGN) et désacidification. Le procédé IFPEXOL se compose de deux sections successives : une première section IFPEX-1 de déshydratation et d'extraction des LGN, une deuxième section IFPEX-2...

  15. Le vécu émotionnel de l'infirmière face aux situations de limitations et d'arrêts de traitements

    OpenAIRE

    Tornay, Damien; Roh, Pierre-Yves

    2010-01-01

    Cette étude sʼinscrit dans une démarche dʼinitiation à la recherche infirmière. Le thème porte sur le rôle infirmier et le vécu émotionnel de lʼinfirmière face à une décision de limitations et dʼarrêts de traitements. Cette recherche est de type exploratoire. Elle a été menée par le biais dʼentretiens semi-directifs avec des infirmiers exerçant leur profession dans un service de soins palliatifs. De plus, elle a été réalisée en binôme avec ma collègue, qui explore la même thématique dans un c...

  16. Procédés hybrides à membranes pour le prétraitement d'eau de mer avant dessalement par osmose inverse

    OpenAIRE

    Tansakul, Chatkaew

    2009-01-01

    Ce travail s’inscrit dans une approche innovante d’intégration de différents procédés membranaires. L’objectif général est l’étude du prétraitement d’eau de mer avant dessalement par osmose inverse afin de réduire le potentiel de colmatage de l’eau vis-à-vis des membranes d’osmose. La démarche adoptée dans cette étude consiste à comparer différents procédés hybrides à membrane : la coagulation couplée à l’ultrafiltration (UF) d’une part et l’adsorption couplée à l’ultrafiltr...

  17. Développement d’un modèle dynamique sous matlab pour un processus anaérobie de traitement des eaux

    OpenAIRE

    ZEGNOUNI, Aymen

    2010-01-01

    Ce mémoire est une contribution à l’étude de la modélisation des bioprocédés pour le traitement des eaux usées par voie anaérobie. La matière organique est dégradée par quatre principales populations bactériologiques en produisant un biogaz composé essentiellement de méthane et de dioxyde de carbone. Des simulations numériques, basées sur les équations du modèle AM2 qui décrit le processus par deux réactions biologiques, ont été effectuées.

  18. Cold-Leg Small Break LOCA Analysis of APR1400 Plant Using a SPACE/sEM Code

    International Nuclear Information System (INIS)

    The Small Break Loss-of-Coolant Accident (SBLOCA) evaluation methodology (EM) for APR1400, called sEM, is now being developed using SPACE code. SPACE/sEM is to set up a conservative evaluation methodology in accordance with appendix K of 10 CFR 50. Major required and acceptable features of the evaluation models are described as below. - Fission product decay : 1.2 times of ANS97 decay curve - Critical flow model : Henry-Fauske Moody two phase critical flow model - Metal-Water reaction model : Baker-Just equation - Critical Heat Flux (CHF) : B and W, Barnett and Modified Barnett correlation - Post-CHF : Groeneveld 5.7 film boiling correlation A series of test matrix is established to validate SPACE/sEM code in terms of major SBLOCA phenomena, e.g. core level swelling and boiling, core heat transfer, critical flow, loop seal clearance and their integrated effects. The separated effect tests (SETs) and integrated effect tests (IETs) are successfully performed and these results shows that SPACE/sEM code has a conservatism comparing with experimental data. Finally, plant calculations of SBLOCA for APR1400 are conducted as described below. - Break location sensitivity : DVI line, hot-leg, cold-leg, pump suction leg. - Break size spectrum : 0.4ft2∼0.02ft2(DVI) 0.5ft2∼0.02ft2(hot-leg, cold-leg, pump suction leg) This paper deals with break size spectrum analysis of cold-leg break accidents. Based on the calculation results, emergency core cooling system (ECCS) performances of APR1400 and typical SBLOCA phenomena can be evaluated. Cold-leg SBLOCA analysis for APR1400 is performed using SPACE/sEM code under harsh environment condition. SPACE/sEM code shows the typical SBLOCA behaviors and it is reasonably predicted. Although SPACE/sEM code has conservative models and correlations based on appendix K of 10 CFR 50, PCT does not exceed the requirement (1477 K). It is concluded that ECCS in APR1400 has a sufficient performance in cold-leg SBLOCA

  19. Development of an amphibious robot for visual inspection of APR1400 Npp IRWST strainer

    International Nuclear Information System (INIS)

    An amphibious inspection robot system (hereafter AIROS) is being developed to visually inspect the in-containment refueling storage water tank (hereafter IRWST) strainer in APR1400 instead of a human diver. Four IRWST strainers are located in the IRWST, which is filled with boric acid water. Each strainer has 108 sub-assembly strainer fin modules that should be inspected with the VT-3 method according to Reg. guide 1.82 and the operation manual. AIROS has 6 thrusters for submarine voyage and 4 legs for walking on the top of the strainer. An inverse kinematic algorithm was implemented in the robot controller for exact walking on the top of the IRWST strainer. The IRWST strainer has several top cross braces that are extruded on the top of the strainer, which can be obstacles of walking on the strainer, to maintain the frame of the strainer. Therefore, a robot leg should arrive at the position beside the top cross brace. For this reason, we used an image processing technique to find the top cross brace in the sole camera image. The sole camera image is processed to find the existence of the top cross brace using the cross edge detection algorithm in real time. A 5-DOF robot arm that has multiple camera modules for simultaneous inspection of both sides can penetrate narrow gaps. For intuitive presentation of inspection results and for management of inspection data, inspection images are stored in the control PC with camera angles and positions to synthesize and merge the images. The synthesized images are then mapped in a 3D CAD model of the IRWST strainer with the location information. An IRWST strainer mock-up was fabricated to teach the robot arm scanning and gaiting. It is important to arrive at the designated position for inserting the robot arm into all of the gaps. Exact position control without anchor under the water is not easy. Therefore, we designed the multi leg robot for the role of anchoring and positioning. Quadruped robot design of installing sole

  20. Development of an amphibious robot for visual inspection of APR1400 Npp IRWST strainer

    Energy Technology Data Exchange (ETDEWEB)

    Jang, You Hyun; Kim, Jong Seog [Korea Hydro Nuclear Power Central Research Institute, Daejeon (Korea, Republic of)

    2014-06-15

    An amphibious inspection robot system (hereafter AIROS) is being developed to visually inspect the in-containment refueling storage water tank (hereafter IRWST) strainer in APR1400 instead of a human diver. Four IRWST strainers are located in the IRWST, which is filled with boric acid water. Each strainer has 108 sub-assembly strainer fin modules that should be inspected with the VT-3 method according to Reg. guide 1.82 and the operation manual. AIROS has 6 thrusters for submarine voyage and 4 legs for walking on the top of the strainer. An inverse kinematic algorithm was implemented in the robot controller for exact walking on the top of the IRWST strainer. The IRWST strainer has several top cross braces that are extruded on the top of the strainer, which can be obstacles of walking on the strainer, to maintain the frame of the strainer. Therefore, a robot leg should arrive at the position beside the top cross brace. For this reason, we used an image processing technique to find the top cross brace in the sole camera image. The sole camera image is processed to find the existence of the top cross brace using the cross edge detection algorithm in real time. A 5-DOF robot arm that has multiple camera modules for simultaneous inspection of both sides can penetrate narrow gaps. For intuitive presentation of inspection results and for management of inspection data, inspection images are stored in the control PC with camera angles and positions to synthesize and merge the images. The synthesized images are then mapped in a 3D CAD model of the IRWST strainer with the location information. An IRWST strainer mock-up was fabricated to teach the robot arm scanning and gaiting. It is important to arrive at the designated position for inserting the robot arm into all of the gaps. Exact position control without anchor under the water is not easy. Therefore, we designed the multi leg robot for the role of anchoring and positioning. Quadruped robot design of installing sole

  1. Conception et exploitation d'une base de métadonnées de traitements informatiques, représentation opérationnelle des connaissances d'expert -- Application au domaine géographique

    OpenAIRE

    Abd-El-Kader, Yann

    2006-01-01

    L'information géographique est construite, analysée et transformée par des traitements informatiques. À l'Institut Géographique National (IGN), les utilisateurs et les développeurs ont besoin d'aide pour rechercher, connaître et partager ces traitements.Le but de notre travail est de fournir cette aide. Les documentations existantes ne permettent pas toujours de répondre de façon satisfaisante aux besoins identifiés : elles sont éparses, aux formats hétérogènes et ne décrivent pas les données...

  2. Tentatives de prétraitement des granulats recyclés pour l’amélioration des bétons préfabriqués

    OpenAIRE

    Zhao, Zengfeng; Courard, Luc; Remond, Sébastien; Damidot, Denis; Fiandaca, Thomas

    2015-01-01

    De très grandes quantités de déchets de construction et de démolition sont produites chaque année. Jusqu'à présent, seule une petite fraction de ces déchets de béton est réutilisée sous forme de granulats pour la fabrication de béton. Afin de faire bon usage des granulats recyclés (GR) dans le béton, il est très important d’améliorer leurs propriétés. Dans cette étude, une méthode de traitement des GR au moyen d’une carbonatation accélérée en laboratoire et des méthodes de traitement par modi...

  3. Amélioration de la durée de vie d'essences de bois peu durables à l'aide d'un traitement combiné boates/huiles végétales

    OpenAIRE

    Lyon, Florent

    2007-01-01

    Le marché de la préservation du bois recherche des alternatives aux traitements anciens, efficaces mais généralement toxiques pour l'environnement comme pour l'Homme. L'étude propose d'évaluer l'amélioration de résistance biologique apportée par l'utilisation de borates combinés à des huiles végétales. Les borates reconnus pour leur efficacité biocide mais lessivés sont en partie retenus par l'ajout d'huile végétale, le tout forme un traitement efficace et à faible impact environnemental cont...

  4. Analysis of MSGTR events for APR1400 by means of best estimate thermal-hydraulic system code

    International Nuclear Information System (INIS)

    A multiple steam generator tube rupture (MSGTR) event has never occurred in the history of commercial nuclear reactor operation while single steam generator tube rupture (SGTR) event is reported to occur every two years. As there is no history of MSGTR event, the understandings of transients and consequences of this event are not so much. In this study, a postulated MSGTR event in advanced power reactor 1400 (APR1400) is analyzed using thermal-hydraulic system code. The APR 1400 is a two-loop, 1000 MWe, PWR supposed to be built in 2009. MARS1.4 is used in this study. The present study aims to understand the effects of rupture location in heat transfer tubes and selection of affected steam generator following a MSGTR event. The effects of five tube rupture locations are compared with each other. The comparison shows that the response of APR1400 is to allow shortest time for operator action following a tubes rupture in the vicinity of hot-leg side tube sheet and to allow longest time following a tube ruptures at the tube top. The MSSV lift time for rupture at tube-top is evaluated as 24.5% larger than that for rupture at hot-leg side tube sheet. Also, the MSSV lift time for four cases are compared in order to examine how long operator response time is allowed depending on which steam generator is affected. The comparison shows that the cases for both of two steam generators are affected allow longer time for operator action compared with the cases that a single steam generator is affected. Further more, the tube ruptures in the steam generator where a pressurizer is linked leads to the shortest operator response time

  5. Regulation of enterobactin iron transport in Escherichia coli: characterization of ent::Mu d(Apr lac) operon fusions.

    OpenAIRE

    Fleming, T P; Nahlik, M S; McIntosh, M A

    1983-01-01

    The vector Mu d(Apr lac) was utilized to construct operon fusions in the Escherichia coli enterobactin (ent) biosynthetic and transport genes. Enzyme assays indicated a 5- to 15-fold increase in the expression of beta-galactosidase when the fusion strains were grown under iron-deficient conditions. The polarity effects seen by Mu d insertions into entA, entC, and entE were consistent with a single operon, entA(CGB)E. The direction of transcription from iron-regulated promoters was determined ...

  6. Pastato aprūpinimas šiluma šilumos siurbliu su šiluminiu poliumi

    OpenAIRE

    Žostautas, Mauricijus

    2012-01-01

    Baigiamajame magistro darbe nagrinėjamas pastato, aprūpinimas šiluma šilumos siurbliu su šiluminiais poliais. Yra apžvelgtos esamos giliosios bei sekliosios geoterminės energijos panaudojimo panaudojimo galimybės Lietuvoje. Aprašytos prielaidos ir supaprastinimai šiluminių polių skaičiavimui, aprašytos skaičiavimo metodikos. Atlikti šiluminių polių skaičiavimai, naudojantis penkiomis metodikomis. Aprašytas pasirinktas pastatas, apskaičiuoti atitvarų šiluminiai rodikliai, nustatyta pastatui re...

  7. Kvartalo/objekto aprūpinimo šilumine energija variantų analizė

    OpenAIRE

    Pladas, Karolis

    2014-01-01

    Magistro baigiamajame darbe aptariamas Lietuvos ir Europos Sąjungos šalių energetikos sektorius. Apžvelgiamos direktyvos, strategijos, plėtros planai bei teisės aktai skirti energetikos plėtojimui šalyje. Tiriamuoju objektu pasirenkama Trakų Vokės katilinė, kuri aprūpina šiluma kvartalą degindama gamtines dujas vandens šildymo katiluose. Šiame darbe yra nagrinėjamos penkios alternatyvos: kogeneratorius ir dujiniai katilai, kogeneratorius su akumuliacine talpa ir dujiniais katilais, kogenerato...

  8. Multi-analytical characterisation of D’Aprés Cormon by José Veloso Salgado

    Energy Technology Data Exchange (ETDEWEB)

    Cardeira, A.M. [Faculdade de Belas-Artes da Universidade de Lisboa, Largo da Academia Nacional de Belas-Artes, 1249-058 Lisboa (Portugal); Centro de Física Atómica da Universidade de Lisboa, Av. Professor Gama Pinto 2, 1649-003 Lisboa (Portugal); Longelin, S. [Centro de Física Atómica da Universidade de Lisboa, Av. Professor Gama Pinto 2, 1649-003 Lisboa (Portugal); Costa, S.; Candeias, A. [Laboratório José de Figueiredo, Direcção Geral do Património Cultural, Rua das Janelas Verdes 37, 1249-018 Lisboa (Portugal); Laboratório HERCULES e Centro de Química de Évora, Universidade de Évora, Largo Marquês de Marialva 8, 7000 Évora (Portugal); Carvalho, M.L. [Centro de Física Atómica da Universidade de Lisboa, Av. Professor Gama Pinto 2, 1649-003 Lisboa (Portugal); Manso, M., E-mail: marta974@cii.fc.ul.pt [Centro de Física Atómica da Universidade de Lisboa, Av. Professor Gama Pinto 2, 1649-003 Lisboa (Portugal)

    2014-07-15

    This case study reveals the analytical characterisation carried out on ‘D’Aprés Cormon’ (1891) by Veloso Salgado, a copy of ‘Caïn’ (1880) by Fernando Cormon, belonging nowadays to Musée d’Orsay. Infrared Reflectography made in situ revealed underdrawing grid that was used to transpose the original painting to a smaller scale, pictorial style, execution method and retouched/restored areas. In situ EDXRF analysis together with Raman microscopy allowed the identification of gypsum, lead white, titanium white, yellow ochre, vermilion, ultramarine and lamp black. These results provide valuable information about the Salgado’s palette and his production technique.

  9. Multi-analytical characterisation of D’Aprés Cormon by José Veloso Salgado

    International Nuclear Information System (INIS)

    This case study reveals the analytical characterisation carried out on ‘D’Aprés Cormon’ (1891) by Veloso Salgado, a copy of ‘Caïn’ (1880) by Fernando Cormon, belonging nowadays to Musée d’Orsay. Infrared Reflectography made in situ revealed underdrawing grid that was used to transpose the original painting to a smaller scale, pictorial style, execution method and retouched/restored areas. In situ EDXRF analysis together with Raman microscopy allowed the identification of gypsum, lead white, titanium white, yellow ochre, vermilion, ultramarine and lamp black. These results provide valuable information about the Salgado’s palette and his production technique

  10. Thermal-Hydraulic Integral Effect Test Result on the Steam Generator Tube Rupture Accident in the APR1400

    International Nuclear Information System (INIS)

    A postulated SGTR (Steam Generator Tube Rupture) event of the APR1400 was experimentally investigated with the thermal-hydraulic integral effect test facility, ATLAS (Advanced Thermal-hydraulic Test Loop for Accident Simulation). It is generally known that the leak flow rate from the primary to the secondary side is the most important factor affecting the overall thermalhydraulic behaviors such as the depressurization rate of the RCS system, the water level increase and pressurization rate of the secondary system, and the consequent MSSV opening time, etc. As one of the most limiting SGTR accidents, a leak flow equivalent to a double-ended rupture of single and five U-tubes was simulated in this study. The main objectives of these tests were not only to provide physical insight into the system response of the APR1400 reactor during a transient situation of the SGTR but also to present integral effect test data for the validation of the SPACE (Safety and Performance Analysis Computer Code), which is now under development by the Korean nuclear industry

  11. A Bayesian inversion for slip distribution of 1 Apr 2007 Mw8.1 Solomon Islands Earthquake

    Science.gov (United States)

    Chen, T.; Luo, H.

    2013-12-01

    On 1 Apr 2007 the megathrust Mw8.1 Solomon Islands earthquake occurred in the southeast pacific along the New Britain subduction zone. 102 vertical displacement measurements over the southeastern end of the rupture zone from two field surveys after this event provide a unique constraint for slip distribution inversion. In conventional inversion method (such as bounded variable least squares) the smoothing parameter that determines the relative weight placed on fitting the data versus smoothing the slip distribution is often subjectively selected at the bend of the trade-off curve. Here a fully probabilistic inversion method[Fukuda,2008] is applied to estimate distributed slip and smoothing parameter objectively. The joint posterior probability density function of distributed slip and the smoothing parameter is formulated under a Bayesian framework and sampled with Markov chain Monte Carlo method. We estimate the spatial distribution of dip slip associated with the 1 Apr 2007 Solomon Islands earthquake with this method. Early results show a shallower dip angle than previous study and highly variable dip slip both along-strike and down-dip.

  12. Feed and Bleed Operation Analysis during Total Loss of Feedwater Accident for Supporting the PSA of APR+

    International Nuclear Information System (INIS)

    For estimating the safety of APR+ design, the probabilistic safety assessment (PSA) is performed. This paper discusses the minimum success criteria for successful feed and bleed procedure verified and decided when the secondary cooling is failed during Total loss of feedwater (TLOFW) accident. For verifying whether the equipment conditions proposed is enough to manage the transient event without core damage, the analysis is performed by RELAP5/MOD 3.3 code. During TLOFW event, the operator's action time is allowed for 80 minutes and the uncovered core could maintain the stable state for a long time, about a half or one hour by the positive effects given by the fast coolant circulation by RCP pump operation. In simulations considering test scenarios, the minimum required equipment for successful F and B managing during TLOFW without LOOP is verified that it is that F and B procedure could be performed successfully as if the operator would open at least one out of four POSRV within 80 minutes after secondary cooling failure for the RCS depressurization. These analysis results can be used for contribute more realistic and accurate performance of a APR+ PSA

  13. Evaluation of Steam and Gas-flow for APR1400 IRWST using GOTHIC 6.1b

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Mun Soo; Lee, Suk Ho; Kim, Han Gon [Korea Hydro and Nuclear Power Co., Daejeon (Korea, Republic of)

    2009-05-15

    The In-Containment Refueling Water Storage Tank (IRWST) of APR1400 is installed at the bottom of the containment building to promote the plant safety functions during an accident. This design feature brings about uncertainty factors that may necessitate improvement or revision of the conventional prediction of temperature and pressure of the containment building in the event of an accident. The hot steam that is released from a RCS break enters the IRWST through four Pressure Relief Dampers (PRDs). The steam is expected to be condensed with water stored in the IRWST, in which water is colder than the incoming steam. The purpose of this study is to investigate the influence of IRWST and PRDs on back pressure and temperature in APR1400 containment by utilizing a containment code: GOTHIC 6.1b (Generation of Thermal-Hydraulic Information for Containments). For this purpose, a multi-compartment and detailed three-dimensional model was developed to predict the steam and gas flow-rate in IRWST.

  14. Unit Risk Quotient (RQ) and Relative Significance of Radionuclide on Flora and Fauna to the EU-APR Optimization

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Keunsung [KHNP-CRI, Daejeon (Korea, Republic of); Kim, Sukhoon [FNC Technology Co., Ltd., Yongin (Korea, Republic of); Lee, Chonghui [KEPCO E and C, Yongin (Korea, Republic of)

    2015-05-15

    As part of the project for acquiring the certification from EUR organization, in accordance with Articles 4.8 and 5.5 specified in Section 2.20 of EUR Volume 2, the effects of ionizing radiation from the standard design of EU-APR on biota and ecosystems during operation and decommissioning phases shall be assessed. This assessment must be carried out according to the ERICA (i.e. Environmental Risk from Ionizing Contaminants: Assessment and management) integrated approach. This paper describes the evaluation results for unit risk quotient and relative significance by radionuclide derived from performing Tier 1 assessment on flora and fauna for the EU-APR design using ERICA Tool. As specified previously, Pa-231 and Th-228 are the most significant for the terrestrial and for the marine/freshwater ecosystems, respectively. And, in terms of environmental risk, those radionuclides having the most impact on flora and fauna are relatively more significant than isotope having the least impact by about 7 to 10 orders of magnitude.

  15. Video-assisted right supradiaphragmatic thoracic duct ligation for non traumatic recurrent chylothorax

    OpenAIRE

    Christodoulou M.

    2006-01-01

    Introduction : Un chylothorax est une pathologie comprenant des manifestations respiratoires, nutritionnelles et immunologiques. La récidive du chylothorax ou l'échec du traitement conservateur imposent un traitement chirurgical. Ce travail rapporte notre expérience de ligature supra-diaphragmatique, vidéo-assistée du canal thoracique, pour chylothorax récurrent non traumatique. Patients et méthodes : Entre 1999 et 2004, nous avons recensé six observations (quatre du côté droit, un du côté ga...

  16. Fistule bilio-pleurale post traumatique: à propos d’un cas

    Directory of Open Access Journals (Sweden)

    Mohamed Smahi

    2010-03-01

    Full Text Available Les fistules bilio thoraciques post traumatiques sont extrêmement rares, leur traitement peut être conservateur mettant en œuvre des techniques de radiologie et d’endoscopie interventionnelle ou chirurgical si échec du premier. Nous rapportons une observation de fistule bilio pleurale post traumatique où l’indication du traitement chirurgical de première intention a été indiscutable vu le sepsis et l’instabilité hémodynamique.

  17. L’INFLUENCE DE L’HERBICIDE GRAMOXONE SUR L’ACTIVITÉ DE LA CATALASE DANS LES GRAINS DE BLÉ ET DE HARICOT AU COURS DE LA GERMINATION

    Directory of Open Access Journals (Sweden)

    Anca Huma

    2003-08-01

    s’accentue avec l’augmentation de sa concentration, et il est plus fort 20 heures après le traitement des caryopses de blé et 48 heures, mais surtout 72 heures après le traitement des grains d’haricot avec cet herbicide.

  18. [Preparation and Identification of High Immunogenic A/PR/8/34 Maternal Strain HA Protein for Influenza Virus Classical Reassortment].

    Science.gov (United States)

    Tang, Jing; Xin, Li; Guo, Junfeng; Zhu, Wenfei; Zhang, Heyuan; Lang, Shaohui; Wang, Dayan; Shu, Yuelong

    2016-03-01

    Preparation of maternal strain A/PR/8/34 HA antiserum for influenza virus classical reassortment. A/PR/8/34 virus was digested by bromelain after inactivation and purification. 5%-20% sucrose continuous density gradient centrifugation method was used to purify HA protein. SIRD method was used to select the target protein. SDS-PAGE method was used to identified HA protein. High Immunogenic A/PR/8/34 HA protein was successfully prepared and HI titer reached 10240. High purity HA antiserum was identified by SIRD method. The key reagent in the classical reassortment of influenza virus was prepared, and the complete set of technical methods were explored, which laid the foundation for the independent research and development of seasonal influenza vaccine strains of China. PMID:27396155

  19. Evaluation of Effect of N{sub 2} Gas on the Cooling Capability of Passive Auxiliary Feedwater System (PAFS) in APR+

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Yun Je; Kang, Kyong Ho; Yun, Byong Jo [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2012-05-15

    In Korea, Advanced Power Reactor Plus (APR+) has being developed by adding passive safety features to Advanced Power Reactor 1400MWe (APR1400). Passive Auxiliary Feedwater System (PAFS) is one of passive system adopted in the APR+ to replace the conventional active auxiliary feedwater system. Because PAFS removes decay heat from the reactor core, it is required to verify the performance of PAFS in postulated accidents cases. In addition, an effect of noncondensable gas on the heat removal capability of PAFS should be evaluated since the non-condensable gas may deteriorate a condensation heat transfer through the condensation heat exchanger in PAFS. In this study, the effect of N{sub 2} gas was evaluated using MARS

  20. Traitements didactiques preventifs d'un type de conceptions erronees en sciences physiques chez des eleves du secondaire

    Science.gov (United States)

    Blondin, Andre

    hypotheses avec la cohorte suivante d'eleves chez qui se repetaient les memes conditions d'apprentissage. Nous avons utilise le design de recherche "posttest only" de Campbell et Stanley. En mai, apres le moment prevu dans la planification du programme pour donner le probleme aux eleves, nous avons suggere deux facons differentes de reviser la solution de ce probleme. Les eleves du premier groupe experimental ont revise sans que soit activee la connaissance anterieure apprehendee de la rotation de la Terre. Les eleves du deuxieme groupe experimental ont ete confrontes, par des questions et une simulation, au fait que la rotation de la Terre n'est pas une connaissance pertinente pour resoudre le probleme. Les groupes temoins et les groupes experimentaux ont ete choisis au hasard dans le bassin des ecoles secondaires de la commission scolaire. (Abstract shortened by UMI.)

  1. Disjonction symphysaire après un accouchement par voie basse dystocique: à propos d'un cas

    Science.gov (United States)

    Laadioui, Meriem; Slimani, Wafae; Jayi, Sofia; Alaoui, Fatimazahra Fdili; Bouguern, Hakima; Chaara, Hikmat; Melhouf, Moulay Aabdelilah

    2014-01-01

    La disjonction symphysaire est une affection rare, qui se définie par un élargissement au niveau de l'articulation inter-symphysaire estimé supérieur à 10 mm. Cette affection nécessite une prise en charge spécialisée en cas de douleurs sévères et invalidantes. Nous rapportant le cas d'une patiente présentant des douleurs pelviennes intense avec impotence du MI gauche à J2 d'un accouchement dystocique, l'examen clinique a objectivé une douleur exquise à la palpation de la symphyse pubienne. Le diagnostic a été confirmé par une radiologie du bassin de face objectivant un élargissement de la symphyse pubienne de 15 mm, la prise en charge thérapeutique a consisté en une mise sous décharge et anti-coagulation préventive avec un traitement antalgique à base de paracétamol et AINS. L’évolution était favorable. A travers notre cas, nous insisterons sur les caractéristiques de cette pathologie notamment pronostic, ce qui permettra au praticien de comprendre l'intérêt du diagnostic et prise en charge précoce de cette entité qu'elle évoquer devant toute douleurs pelviennes survenant au cours de la grossesse ou en post partum. PMID:24932344

  2. The subtilisin-like protease AprV2 is required for virulence and uses a novel disulphide-tethered exosite to bind substrates.

    Directory of Open Access Journals (Sweden)

    Ruth M Kennan

    Full Text Available Many bacterial pathogens produce extracellular proteases that degrade the extracellular matrix of the host and therefore are involved in disease pathogenesis. Dichelobacter nodosus is the causative agent of ovine footrot, a highly contagious disease that is characterized by the separation of the hoof from the underlying tissue. D. nodosus secretes three subtilisin-like proteases whose analysis forms the basis of diagnostic tests that differentiate between virulent and benign strains and have been postulated to play a role in virulence. We have constructed protease mutants of D. nodosus; their analysis in a sheep virulence model revealed that one of these enzymes, AprV2, was required for virulence. These studies challenge the previous hypothesis that the elastase activity of AprV2 is important for disease progression, since aprV2 mutants were virulent when complemented with aprB2, which encodes a variant that has impaired elastase activity. We have determined the crystal structures of both AprV2 and AprB2 and characterized the biological activity of these enzymes. These data reveal that an unusual extended disulphide-tethered loop functions as an exosite, mediating effective enzyme-substrate interactions. The disulphide bond and Tyr92, which was located at the exposed end of the loop, were functionally important. Bioinformatic analyses suggested that other pathogenic bacteria may have proteases that utilize a similar mechanism. In conclusion, we have used an integrated multidisciplinary combination of bacterial genetics, whole animal virulence trials in the original host, biochemical studies, and comprehensive analysis of crystal structures to provide the first definitive evidence that the extracellular secreted proteases produced by D. nodosus are required for virulence and to elucidate the molecular mechanism by which these proteases bind to their natural substrates. We postulate that this exosite mechanism may be used by proteases produced by

  3. Monoclinically distorted perovskites, A2ZnTiO6 (A=Pr, Gd): Rietveld refinement, and dielectric studies

    International Nuclear Information System (INIS)

    Double perovskite related oxide A2ZnTiO6A=Pr, Gd were synthesized by the solid state reaction method at 1523 K. The structure and microstructure of the compounds were studied by X-ray, SAED and FESEM. Rietveld refinement of the powder X-ray analysis shows that the compounds crystallizes in monoclinic space group P21/n (a+b−b−) with unit cell parameter √2ap×√2ap×2ap (a=5.5026(1) Å, b=5.6305(1) Å, c=7.8149(1) Å, β=90.02(1)° for Pr2ZnTiO6 and a=5.3621(1) Å, b=5.6565(2) Å, c=7.6779(2) Å and β=90.264(2)° for Gd2ZnTiO6. Electron diffraction study confirms P21/n symmetry of the oxides. The monoclinic distortion is larger in Gd2ZnTiO6 than Pr2ZnTiO6 which is associated with the tolerance factor and the tilting angle of ZnO6 and TiO6 octahedra (ϕ=13.64° for Pr2ZnTiO6 and 16.51° for Gd2ZnTiO6). The compounds are highly ordered. The charge and size difference between B site cations are the driving force for the ordering of the B′O6 and B″O6 octahedra. Pr2ZnTiO6 shows a dielectric constant of 27 and dielectric loss of 0.003 while Gd2ZnTiO6 has a dielectric constant of 17 and dielectric loss of 0.005 measured at 1 MHz. - Graphical abstract: Synthesis of new double perovskite dielectric material with very low dielectric loss. - Highlights: • Synthesis of new monoclinically distorted double perovskite (Pr2ZnTiO6). • Synthesis of monoclinically distorted double perovskite (Gd2ZnTiO6). • Selected area electron diffraction study of A2ZnTiO6 (A=Pr, Gd). • Study of dielectric properties of A2ZnTiO6 (A=Pr, Gd)

  4. Strong synergy with APR-246 and DNA-damaging drugs in primary cancer cells from patients with TP53 mutant High-Grade Serous ovarian cancer

    OpenAIRE

    Fransson, Åsa; Glaessgen, Daria; Alfredsson, Jessica; Wiman, Klas G.; Bajalica-Lagercrantz, Svetlana; Mohell, Nina

    2016-01-01

    Background Mutation in the tumor suppressor gene TP53 is an early event in the development of high-grade serous (HGS) ovarian cancer and is identified in more than 96 % of HGS cancer patients. APR-246 (PRIMA-1MET) is the first clinical-stage compound that reactivates mutant p53 protein by refolding it to wild type conformation, thus inducing apoptosis. APR-246 has been tested as monotherapy in a Phase I/IIa clinical study in hematological malignancies and prostate cancer with promising result...

  5. Evolution a court terme des formes du phosphore d'un sol ferrallitique apres apports d'une boue urbaine

    OpenAIRE

    Brossard, M.; Mench, Michel; CLAIRON, Maurice; Laurent, J.Y.

    1991-01-01

    Une boue urbaine a été incorporée aux doses de 10 et 100 t (MS)●ha-1 dans l’horizon 0-20 cm d’un sol ferrallitique de Guadeloupe. L’expérimentation est conduite en microparcelles de plein champ pendant 500 j. Après prélèvement des échantillons de sol, les mottes de boue non fragmentées de taille supérieure à 5 mm sont triées manuellement. Les formes du phosphore du sol analysées sont les suivantes : phosphore total (Pt), organique (Po), minéral (Pm), extrait par un mélange bicarbonate-f...

  6. O après-coup e a reconsolidação da memória

    Directory of Open Access Journals (Sweden)

    Graziele Luiza Barizon Scopel Gerbasi

    2015-04-01

    Full Text Available Em diferentes áreas do conhecimento é reconhecido que a memória está sujeita a transformações ao longo do tempo. Partindo desse pressuposto, o objetivo do presente estudo é apresentar uma discussão compreendendo a ideia de que nossas recordações são suscetíveis a transformações e a concepção de après-coup. Há o delineamento de algumas ideias acerca da temporalidade em Psicanálise e do mecanismo de reconsolidação da memória segundo as Neurociências. Utilizando-se tais conceitos, evidenciou-se a viabilidade de se pensar uma interlocução entre a Psicanálise e as Neurociências.

  7. Fernand Braudel : Civilisation matérielle, Economie et Capitalisme trente ans après

    OpenAIRE

    Garner, Guillaume

    2013-01-01

    Trente ans après la publication par Fernand Braudel de sa trilogie Civilisation matérielle, Économie et Capitalisme XVe-XVIIIe siècle, l’IFHA (Guillaume Garner) et le Global and European Studies Institute de l’Université de Leipzig (Matthias Middell) se sont associés pour organiser une journée d’études franco-allemande, qui s’est tenue à Leipzig le 2 octobre 2009, dont le but était moins de discuter de la pertinence des conclusions formulées par F. Braudel que d’évaluer, sur le plan des probl...

  8. 返工设备——APR-5000-XLS阵列封装返工系统

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Metcal公司2001年推出阵列封装返工系统,确立了可重复性、精度和温度控制的新标准。该公司最近推出的APR-5000-XLS阵列封装返工系统,再次确立了精确、有成本效益的、最大范围元件类型的返工基准,可处理BGA,CSP,LGA(Land Grid Array),Micro SMD,MLF(Micro-Lead Frame),BCC(Bumped Chip Component)多种封装。

  9. 返工设备——APR-5000-XLS阵列封装返工系统

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    APR-5000-XLS阵列封装返工系统可处理BGA,CSP,LGA(Land Grid Array),Micro SMD,MLF(Micro—Lead Frame),BCC(Bumped Chip Component)多种封装。其可处理的板尺寸达610mm×610mm(24.5″×24.5″),厚度达6.35mm(0.25″)。双程、全空气底部预热,能处理大小不同规格的PCB板。采用5个热电偶输入和闭环RTD温度控制,

  10. O après-coup e a reconsolidação da memória

    OpenAIRE

    Graziele Luiza Barizon Scopel Gerbasi; Paulo José da Costa

    2015-01-01

    Em diferentes áreas do conhecimento é reconhecido que a memória está sujeita a transformações ao longo do tempo. Partindo desse pressuposto, o objetivo do presente estudo é apresentar uma discussão compreendendo a ideia de que nossas recordações são suscetíveis a transformações e a concepção de après-coup. Há o delineamento de algumas ideias acerca da temporalidade em Psicanálise e do mecanismo de reconsolidação da memória segundo as Neurociências. Utilizando-se tais conceitos, evidenciou-se ...

  11. Performance and scenario evaluation of PAFS through the LOFW accident in APR1400 by using MARS code

    International Nuclear Information System (INIS)

    In order to enhance the safety feature of the APR1400 through the passive ways, the passive auxiliary feedwater system(PAFS) is under preliminary consideration by KAERI. For the successful adaptation of PAFS, accident scenario evaluation of PWR plant that is assumed to have the PAFS system should be performed. Condensing heat exchanger assemblies are installed at the exterior boundary of the containment building per one steam generator. The performance of the heat exchanger is designed to remove the decay heat of the fuel completely. In normal operation condition, PAFS system is not connected with the steam and feed lines. A Total Loss of Feed Water(TLOFW) accident is selected for the performance and scenario evaluation after the severity check. The PAFS connection valves are open at the signal of 25% level trip of steam generator. With the single failure assumption of PAFS open valve, the scenario propagations are calculated by using MARS code

  12. Performance and scenario evaluation of PAFS through the LOFW accident in APR1400 by using MARS code

    Energy Technology Data Exchange (ETDEWEB)

    Bae, Sung Won; Bae, Byoung Uhn; Yun, Byong Jo [Korea Atomic Energy Institute, Daejeon (Korea, Republic of)

    2009-07-01

    In order to enhance the safety feature of the APR1400 through the passive ways, the passive auxiliary feedwater system(PAFS) is under preliminary consideration by KAERI. For the successful adaptation of PAFS, accident scenario evaluation of PWR plant that is assumed to have the PAFS system should be performed. Condensing heat exchanger assemblies are installed at the exterior boundary of the containment building per one steam generator. The performance of the heat exchanger is designed to remove the decay heat of the fuel completely. In normal operation condition, PAFS system is not connected with the steam and feed lines. A Total Loss of Feed Water(TLOFW) accident is selected for the performance and scenario evaluation after the severity check. The PAFS connection valves are open at the signal of 25% level trip of steam generator. With the single failure assumption of PAFS open valve, the scenario propagations are calculated by using MARS code.

  13. Conceptual design of passive containment cooling system with air holdup tanks in the concrete containment of improved APR+

    Energy Technology Data Exchange (ETDEWEB)

    Jeon, Byong Guk; NO, Hee Cheon, E-mail: hcno@kaist.ac.kr

    2014-02-15

    Highlights: • Conceptual design of passive containment cooling system (PCCS) based on APR+ is proposed. • Decay heat removal rate is to be maximized by introducing air holdup tanks (AHT). • Only air is transported into the AHT decreasing air mass fraction near HXs inside containment and increasing heat transfer rates. • Large AHT volume gives significantly higher heat removal rate. • External HXs have merits over in-tube HXs for long term cooling. - Abstract: The accident of the Fukushima nuclear power plant emphasized passive systems against prolonged station blackout. This paper aims at conceptual design of passive containment cooling system (PCCS) based on APR+, an advanced PWR developed in Korea with passive auxiliary feedwater system (PAFS). In the design, decay heat removal rate is to be maximized by introducing air holdup tanks (AHT). The AHT is an isolated space disposed above IRWST and is connected to the containment free space by vent lines through IRWST water and PAFS heat exchangers (HXs), where steam generated by decay heat is condensed. Since a lot of steam is condensed through in-tube HXs and IRWST water, air is mainly transported into the AHT decreasing air mass fraction near HXs inside containment and increasing heat transfer rates. Several design options (AHT volume, flow distribution in vent lines, HX types) are evaluated via scoping analysis. The scoping analysis had proved that AHT (>10% containment volume) decreased the required number of PCCS HXs to be installed less than a half, failure of valves caused marginal increase in HXs to be installed, and external HXs had merits over in-tube HXs for long term cooling.

  14. Design of condensation heat exchanger for the PAFS (Passive Auxiliary Feedwater System) of APR+ (Advanced Power Reactor Plus)

    International Nuclear Information System (INIS)

    Highlights: ► Condensation heat exchanger for the PAFS (Passive Auxiliary Feedwater System) was designed. ► The requirement of the heat removal rate and the prevention of water hammer phenomena were considered. ► The proposed design of the heat exchanger satisfied the requirement of the passive heat removal system. - Abstract: The APR+ (Advanced Power Reactor Plus), a next generation nuclear power plant in Korea, has adopted the PAFS (Passive Auxiliary Feedwater System) on the secondary system of the steam generator (SG) as an advanced safety feature. It is intended to replace the conventional auxiliary feedwater system, which consists of active components for the SG in a passive way. It removes decay heat from the reactor core by cooling down the secondary system of the SG using a condensation heat exchanger installed in the PCCT (Passive Condensation Cooling Tank). The objective of this study is to design a condensation heat exchanger for the PAFS and to evaluate the cooling performance for the proposed design using the thermal hydraulic system analysis code, MARS (Multi-dimensional Analysis for Reactor Safety). Requirements such as the heat removal capacity and the prevention of water hammer were preferentially considered to determine the design parameters of the heat exchanger tube. The MARS code analysis result showed that the proposed design of the PAFS heat exchanger is able to cool down the required amount of decay heat. The distribution of a liquid volume fraction and flow regime predicted by the MARS code shows that the proposed design of the heat exchanger excludes the water hammer inside the tube. Estimation of a two-phase flow pressure drop indicates that the pressure drop inside the tube is negligible compared to the total pressure drop in the PAFS. From the MARS code analysis, it is concluded that the proposed design of the condensation heat exchanger in the PAFS satisfies the overall criteria for the performance of the passive heat removal

  15. Hématome spontané du méso de l'angle colique droit et du colon transverse compliquant un traitement par anti vitamine K: à propos d'un cas et revue de la littérature

    Science.gov (United States)

    Traoré, Ibrahim Alain; Zaré, Cyprien; Barro, Sié Drissa; Guibla, Ismaël

    2016-01-01

    L'hématome spontané du méso de l'angle colique droit et du transverse est une complication rare du traitement anticoagulant par antivitamine K. Nous rapportons un cas d'hématome spontané du méso de l'angle colique droit et du transverse associé à un hémopéritoine de grande abondance chez un patient traité par antivitamine K pour embolie pulmonaire consécutive à une fracture des plateaux tibiaux droits. Le diagnostic doit être fait en urgence. L’échographie abdominale et la tomodensitométrie confirment le diagnostic. Le traitement non opératoire est la règle. Le traitement chirurgical est indiqué en cas de complications telles que la rupture de l'hématome. PMID:27217878

  16. APR-246 (PRIMA-1(MET)) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines.

    Science.gov (United States)

    Deben, Christophe; Lardon, Filip; Wouters, An; Op de Beeck, Ken; Van den Bossche, Jolien; Jacobs, Julie; Van Der Steen, Nele; Peeters, Marc; Rolfo, Christian; Deschoolmeester, Vanessa; Pauwels, Patrick

    2016-06-01

    APR-246 (PRIMA-1(Met)) is able to bind mutant p53 and restore its normal conformation and function. The compound has also been shown to increase intracellular ROS levels. Importantly, the poly-[ADP-ribose] polymerase-1 (PARP-1) enzyme plays an important role in the repair of ROS-induced DNA damage. We hypothesize that by blocking this repair with the PARP-inhibitor AZD2281 (olaparib), DNA damage would accumulate in the cell leading to massive apoptosis. We observed that APR-246 synergistically enhanced the cytotoxic response of olaparib in TP53 mutant non-small cell lung cancer cell lines, resulting in a strong apoptotic response. In the presence of wild type p53 a G2/M cell cycle block was predominantly observed. NOXA expression levels were significantly increased in a TP53 mutant background, and remained unchanged in the wild type cell line. The combined treatment of APR-246 and olaparib induced cell death that was associated with increased ROS production, accumulation of DNA damage and translocation of p53 to the mitochondria. Out data suggest a promising targeted combination strategy in which the response to olaparib is synergistically enhanced by the addition of APR-246, especially in a TP53 mutant background. PMID:26975633

  17. Apports et limites du traitement de texte dans une tâche de rédaction en L2 Benefits and limits of word processing in a writing task in L2

    Directory of Open Access Journals (Sweden)

    Michèle Catroux

    2012-03-01

    Full Text Available L’expérimentation décrite dans cet article a été conduite auprès de jeunes apprenants d’anglais afin de déterminer les effets de l’utilisation du traitement de texte sur la conduite d’une tâche collaborative de production écrite. L’objet de cette recherche était d’analyser les stades de planification, mise en mots et révision opérés par les élèves. Les verbalisations pendant le travail, les phases rédactionnelles et les performances du groupe travaillant avec le traitement de texte ont été comparées à celles du groupe travaillant sur support papier. L’analyse des variations a permis d’estimer le degré de la surcharge cognitive liée à la manipulation de l’ordinateur et les apports du traitement de texte.The experiment described in the article has been carried out with young learners of English so as to determine the effects of word processing on a collaborative writing task. The purpose of this research was to analyse the stages of planning, translating and reviewing implemented by the learners. The verbalizations during their work, the writing phases and the performance of the group working with a word-processor have been compared to those of the group working with pen and paper. The analysis of the variations made it possible to estimate the degree of cognitive overload in relation to the use of the computer and the benefits of word processing.

  18. La conception incrémentale de jeux sérieux musicaux pour la santé : théorie et application au traitement des troubles du comportement et de la maladie d'Alzheimer

    OpenAIRE

    Benveniste, Samuel

    2010-01-01

    Le jeu sérieux pour la santé (ludicament) est un domaine en pleine expansion dont les acteurs se proposent de rendre la prise en charge médicale plus motivante en y introduisant du "fun". De même, la musicothérapie encourage la recherche du "fun" musical et est de plus en plus plébiscitée par soignants et patients, notamment dans le cadre du traitement des troubles du comportement (Autisme, troubles limites...) et des maladies neuro-dégénératives (Alzheimer, Parkinson...). Pour profiter des s...

  19. Une démarche agronomique pour accompagner le changement technique. Cas de l'emploi du traitement herbicide dans les systèmes de culture à sorgho repiqué au Nord-Cameroun

    OpenAIRE

    Mathieu, Bertrand

    2005-01-01

    Le développement de la culture du sorgho de saison sèche, qui concerne l'ensemble du bassin du lac Tchad, constitue la dynamique agraire la plus visible de ces dernières décennies dans les plaines de l'Extrême-Nord Cameroun. La plante est repiquée dans des terres argileuses plus ou moins inondables, difficilement cultivables en saison des pluies, et accomplit son cycle à partir de la réserve en eau du sol. Le traitement herbicide, introduit récemment, est utilisé de façon croissante compte te...

  20. Développement d’un implant biodégradable à base de gentamicine et de monoléine destiné au traitement des ostéomyélites chroniques

    OpenAIRE

    Ouedraogo, Moustapha

    2008-01-01

    L’ostéomyélite chronique est une infection chronique du tissu osseux et de la moelle. C’est une infection grave du fait de sa localisation au sein d’un tissu profond, de la complexité de sa prise en charge thérapeutique et de la mise en jeu du pronostic fonctionnel. L’incidence de l’ostéomyélite chronique est accrue sur certains terrains (drépanocytose, diabète, et polyarthrite rhumatoïde entre autres). Son traitement classique repose sur un curettage chirurgical associé à une antibiothérapie...

  1. Technologies propres : Méthodes de minimisation des rejets et de choix des procédés de valorisation des effluents. Application aux ateliers de traitement de surface.

    OpenAIRE

    Laforest, Valérie

    1999-01-01

    Le traitement des eaux constitue actuellement la part essentielle des investissements industriels pour la protection de l'environnement. En France, les moyens consacrés à la dépollution des eaux sont de l'ordre de 20 milliards de Francs dont la plus grosse part est consacrée à l'activité industrielle. Les actions engagées se font par une gestion globale des effluents en privilégiant les actions de réduction à la source notamment par la mise en place de technologies propres (optimisation, chan...

  2. Bilans énergétiques et environnementaux des systèmes type dans les filières biogaz : Application au traitement des boues résiduaires en France

    OpenAIRE

    ALMANSOUR, Essam; BONNET, Jean-François

    2010-01-01

    Le biogaz constitue, dans l’optique des transports durables, une solution possible pour la production de carburant renouvelable. Les bilans énergétiques et environnementaux doivent être produits et comparés afin d’évaluer les alternatives en bilan global. Pour la France, une filière type décrivant le traitement par méthanisation des boues des stations d’épurations urbaines en France a été définie et étudiée par enquêtes techniques, sous la forme de systèmes type. Le bilan environnemental est ...

  3. Le traitement des déchets polymères : la valorisation énergétique ou chimique Treatment of Polymer Wastes: Chemical Or Energy Upgrading

    Directory of Open Access Journals (Sweden)

    Dawans F.

    2006-11-01

    Full Text Available Une protection accrue de l'environnement requiert la mise en place de nouvelles techniques fiables et économiques de traitement des déchets polymères. Parmi les diverses méthodes envisagées pour la réutilisation ou l'élimination des polymères usagés, les recyclages énergétiques et chimiques peuvent apporter des solutions satisfaisantes et complémentaires au recyclage de la matière. Cet article fait le point sur l'état d'avancement des techniques de valorisation énergétique et chimique des rejets de polymères et il propose une analyse critique des traitements actuels. Increased environmental protection requires the installation of new treatment techniques for polymer wastes. Competitive industrial facilities are not available from the economic standpoint for recycling spent plastic and rubber wastes in the form of materials, especially when mixtures are involved. It is only by using other treatment method for the chemical or energy upgrading of polymers, as a supplement to the recycling of materials, that it should be possible to make a significant reduction in the amount of spent polymers currently being scrapped. The energy upgrading of wastes by incineration with energy recovery or by pyrolysis with the formation of fuels in an interesting approach for a great many countries. When no reuse is possible, the energy content of the material is upgraded before the subsequent scrapping of an ultimate residue that is reduced to its incompressible minimum after having been inerted. There are currently several technical solutions for incineration furnaces and the treatment of the fumes produced, which meet the more and more severe requirements concerning environmental protection. Incineration systems with energy recovery can recover about 8000 thermies per ton of unsorted plastics. They already have an important position, albeit a varying one, from one European country to another (Table 6. They should develop considerably further in

  4. L’amitié dans la relation ethnographique. Traitement de l’individu et rapport à l’autre dans les groupes locaux de Hijra (Delhi, Inde

    Directory of Open Access Journals (Sweden)

    Emmanuelle Novello

    2009-03-01

    Full Text Available L’amitié dans la relation ethnographique. Traitement de l’individu et rapport à l’autre dans les groupes locaux de Hijra (Delhi, Inde. « Tu es mon amie. Tu es la seule qui me comprenne. » Ces mots, toujours les mêmes, sont revenus sans cesse lors de l’enquête ethnographique que j’ai menée auprès des Hijra de Delhi. Les Hijra forment une catégorie sociale panindienne. Elles sont nées biologiquement hommes ou hermaphrodites, s’habillent et se parent continuellement comme des femmes et, parfois, sont émasculées. Les ethnologues parlent parfois de leur relation avec leurs informateurs en terme d’amitié sans que cette relation soit exprimée et pensée comme telle par ces derniers. Qu’en est-il lorsque la société étudiée désigne l’ethnologue en tant qu’ami et lorsque cette désignation transforme la nature des rapports qu’elle entretenait auparavant avec lui ? L’étude de l’amitié que les Hijra me proposèrent fournira, en premier lieu, un exemple de la façon dont l’ethnologue peut se trouver engagé dans ce rapport affectif. Il s’agira de qualifier cette relation ethnographique par la description du processus d’évolution de mon rôle d’une part, et par l’examen des comportements et des pratiques qui la sanctionnent et qui y sont engagés d’autre part. Cette réflexion sur les représentations et les valeurs auxquelles mes interlocutrices faisaient référence en me conférant la place d’amie, informera en second lieu sur le traitement de l’individu et de l’altérité prévalant dans la catégorie sociale « Hijra ».Friendship in ethnographical relations. Treatment of the individual and relation to the other in local groups of Hijra (Delhi, India. “You are my friend. You are the only person who understands me.” These words, always the same, were endlessly repeated during my ethnographical survey of the Hijra of Delhi. The Hijra form a pan-Indian social category. Born

  5. Thermodynamic Aspects of Supercritical Fluids Processing: Applications of Polymers and Wastes Treatment Aspects thermodynamiques des procédés mettant en oeuvre des fluides supercritiques : applications aux traitements des polymères et des déchets

    Directory of Open Access Journals (Sweden)

    Beslin P.

    2006-11-01

    , fibres et substrats (produits pharmaceutiques, explosifs, revêtements, pour le séchage des matériaux (gels. Cet article présente les propriétés physicochimiques exceptionnelles des fluides supercritiques en rapport avec leurs applications en ingénierie. Après un bref rappel des concepts fondamentaux relatifs au comportement critique des fluides purs, nous développons d'une manière plus détaillée les propriétés physicochimiques ajustables des fluides dans le domaine supercritique. La deuxième partie de l'article décrit les applications en ingénierie des fluides supercritiques relatives aux réactions chimiques et au traitement des polymères. Chaque présentation d'application est divisée en deux parties : la première rappelle les concepts de base et le contexte général ainsi que les propriétés physicochimiques, la seconde développe les applications en ingénierie se rapportant au domaine concerné.

  6. Les politiques d’employabilité en Belgique : traitement clinique des chômeurs et traitement statistique du chômage The Politics of Employability in Belgium : Clinical Treatment of the Unemployed and Statistical Treatment of Unemployment

    Directory of Open Access Journals (Sweden)

    Jean-François Orianne

    2011-03-01

    Full Text Available Cet article interroge la mise en œuvre et le suivi des politiques européennes d’employabilité en Belgique à la lumière de la sociologie de Norbert Elias, en reliant les dimensions sociogénétiques et psychogénétiques de la construction européenne. Le traitement clinique des chômeurs, qui repose principalement sur la construction professionnelle de troubles de l’employabilité, contribue à l’intériorisation de normes à grande échelle, à la socialisation de la population active au marché du travail et renforce la concurrence entre les actifs occupés et les actifs inoccupés (principale condition de stabilité de la monnaie unique. Parallèlement, le traitement statistique du chômage, qui consiste en un jeu rationnel entre États (et Régions de maximisation des indicateurs de résultats, renforce la compétition territoriale pour attirer les investisseurs et encadre, légitime, dynamise ce mouvement incertain d’harmonisation ou d’intégration des systèmes de protection sociale en Europe.This article investigates the setting up and follow-up of European employment politics in Belgium, in light of the sociology of Norbert Elias, in blending the socio-genetic and psycho-genetic dimensions of European construction. The clinical treatment of the unemployed, principally based on the professional construction of employability troubles, contributes to the internalization of standards on a vast scale, to the socialization of the active population on the job market and reinforcing competition between occupied actives and unoccupied actives (a principal condition for the stability of a unique currency. At the same time, the statistical treatment of unemployment, consisting in a deliberate game between States (and Regions of maximization of result indicators, reinforces a territorial competition aimed at attracting investors as well as organizing, legitimating and dynamizing the unsteady movement toward harmonization or

  7. Première expérience de l'utilisation du Misoprostol comme soin après avortement (SAA) à Libreville, Gabon

    OpenAIRE

    Mayi-Tsonga, Sosthène; Minkobame, Ulysse; Mbila, Arielle; Assoumou, Pamphile; Diop, Ayisha; Winikoff, Beverly

    2014-01-01

    Introduction Une étude a été menée afin de déterminer le taux d'acceptabilité de 400µg de misoprostol par voie sublinguale comme traitement de première intention de l'avortement incomplet et de préciser le taux d'avortement complet ou vacuité utérine. Méthodes Les femmes éligibles avaient un diagnostic clinique d'avortement incomplet avec une taille utérine inférieure à celle d'un utérus de 12 semaines d'aménorrhées (SA). Chacune a reçu 400µg de misoprostol par voie sublinguale. Les femmes on...

  8. A systematic core design method for reduction of critical boron concentration in APR 1400 with gadolinia-bearing assembly

    International Nuclear Information System (INIS)

    Highlights: • A systematic core design method reduces CBC of APR 1400. • The core design method solves a non-linear programming problem. • The solution is a set of new Gd-bearing fuel assembly design. • LP loading new Gd-bearing fuel assembly designs achieves target CBCs. • Lower L/H ratio shows longer hold-down effect than higher L/H ratio. - Abstract: A systematic core design method is developed to design Gd-bearing fuel assembly having two types of Gd rods, low-wt%-Gd rod and high-wt%-Gd rod. The purpose of the method is to lower the critical boron concentration (CBC) of a preliminary core loading pattern, and consequently to achieve more negative or less positive moderator temperature coefficient (MTC). The proposed core design method is a process of solving a non-linear programming problem stated with a system of equations. In this method, both the ratio of the number of low-wt%-Gd rod to the number of high-wt%-Gd rod (r) and the assembly average Gd wt% (w) are the solution variables of the system of equations. The target function is the amount of soluble boron concentration reduction, ΔCBC, which is correlated with the reactivity change, ΔkFA, per Gd-bearing fuel assembly by a quadratic reactivity equation. The coefficients of the quadratic equations are calculated prior to the determination of Gd-bearing fuel assembly pattern, using the least square method. The constraints required to determine (r, w) are physically realizable Gd rods pattern, Δki close to ΔkFA derived from ΔCBC, etc. An objective function, min[f(∑i(ΔkFA-Δki))], enables a final loading pattern to reach a target CBC. This design methodology is applied to APR 1400. Total six cases with various target CBCs are investigated to validate the proposed method. CASMO-3/MASTER calculations with new design assemblies produce lower CBCs at BOC than target CBCs keeping maximum pin power below the safety limit, and thus show more negative MTC

  9. APR-246/PRIMA-1(MET) rescues epidermal differentiation in skin keratinocytes derived from EEC syndrome patients with p63 mutations.

    Science.gov (United States)

    Shen, Jinfeng; van den Bogaard, Ellen H; Kouwenhoven, Evelyn N; Bykov, Vladimir J N; Rinne, Tuula; Zhang, Qiang; Tjabringa, Geuranne S; Gilissen, Christian; van Heeringen, Simon J; Schalkwijk, Joost; van Bokhoven, Hans; Wiman, Klas G; Zhou, Huiqing

    2013-02-01

    p53 and p63 share extensive sequence and structure homology. p53 is frequently mutated in cancer, whereas mutations in p63 cause developmental disorders manifested in ectodermal dysplasia, limb defects, and orofacial clefting. We have established primary adult skin keratinocytes from ectrodactyly, ectodermal dysplasia, and cleft lip/palate (EEC) syndrome patients with p63 mutations as an in vitro human model to study the disease mechanism in the skin of EEC patients. We show that these patient keratinocytes cultured either in submerged 2D cultures or in 3D skin equivalents have impaired epidermal differentiation and stratification. Treatment of these patient keratinocytes with the mutant p53-targeting compound APR-246/PRIMA-1(MET) (p53 reactivation and induction of massive apoptosis) that has been successfully tested in a phase I/II clinical trial in cancer patients partially but consistently rescued morphological features and gene expression during epidermal stratification in both 2D and 3D models. This rescue coincides with restoration of p63 target-gene expression. Our data show that EEC patient keratinocytes with p63 mutations can be used for characterization of the abnormal molecular circuitry in patient skin and may open possibilities for the design of novel pharmacological treatment strategies for patients with mutant p63-associated developmental abnormalities. PMID:23355676

  10. A study on issues and solutions about logic functions applied to computerized procedure system in APR1400

    International Nuclear Information System (INIS)

    Plant procedures are instructions to guide operators in monitoring, decision making, and controlling nuclear power plants(NPPs). While plant procedures historically have been paper-based, computerized-based procedures are being developed to overcome the drawbacks of paper-based procedures. The CPS is used to integrate the operational instructions, plan process information and computerized operator support functions in advanced main control room (MCR) of APR1400. The logic functions applied to CPS are three categories: Procedure Entry Condition (PEC), Continuously Applied Step (CAS) re-execution condition, instruction evaluation. This automation using logic function can reduce operator 2019's burden about monitoring, decision making, controlling NPPs but this automation can also lower situation awareness and operator in the loop. These automation issues caused by logic function shall be closed to apply computerized procedure. This paper introduces issues drawn by system designer, plant operators, and human factors engineers. To close these introduced issues, this paper suggests solutions from system design, procedure writer's guideline, and operator training. This paper introduces issues drawn by system designer, plant operators, and human factors engineers. To close these introduced issues, this paper suggests solutions from system design, procedure writer's guideline, and operator training

  11. The fifteenth period report on the cooperative utilization of the AVF cyclotron at Osaka University RCNP (Dec 1982 - Apr 1983)

    International Nuclear Information System (INIS)

    The AVF cyclotron at the RCNP (Research Center for Nuclear Physics) of Osaka University has been cooperatively used by various researchers of Japanese universities or colleges. This collective report covers papers concerning various studies performed at the AVF during Dec 1982 to Apr 1983. Some of the titles of these papers are as follows : Elastic scattering of 56 MeV polarized deuterons from 12C and 40Ca ; Pionic three-nucleon capture reactions ; Measurement on branching ratios of short-lived beta emitter 23Mg and its hyperfine interactions ; Half-life and branching ratios of short-lived beta emitter 13O ; 7Li excitation of the giant resonances in 208Pb ; Measurements of spin polarization of residual nuclei after light particle emission in heavy ion reactions ; Target dependence of the sequential alpha decay through the narrow resonances of 20Ne ; Analyzing power of neutron continuum spectra for the 93Nb (p,nx) reaction and a simple one step OWBA analysis ; Energy dependence of the reaction mechanism for the 3He and alpha induced reactions ; Medium energy gamma rays following radiative capture of polarized protons on light nuclei. (Aoki, K.)

  12. A condensation heat transfer model for nearly horizontal tubes of the Passive Auxiliary Feedwater System in APR+

    International Nuclear Information System (INIS)

    A new condensation heat transfer model based on the flow regime in the nearly horizontal tube has been developed for the Passive Auxiliary Feed-water System (PAFS) of Korean Advanced Power Reactor Plus (APR+). This study focused on the stratified flow in horizontal tubes in which two different heat transfer mechanisms are involved. The void fraction was determined from the 1-D separated flow model (SFM) which incorporates closure relations for shear stress defined by single-phase based expressions and geometric relations for a concave interface using the eccentric circles. The wetted angle proposed by Hart's correlation (1989) was used to classify flow regimes into annular, stratified-wavy and stratified-smooth flow. The new film condensation heat transfer correlation based on Nusselt's integral analysis (1916) was proposed to predict the heat transfer coefficient affected by the vapor flow on the upper portion of tube in the stratified flow. Furthermore, the convective heat transfer correlation for single-phase heat transfer was used to predict the heat transfer coefficient for condensate flowing on the entire perimeter of annular flow and the bottom of the stratified flow. Both heat transfer correlations use Reynolds number based on the phasic actual velocities and geometric variables obtained from SFM. Finally, the new condensation heat transfer model package was evaluated against available experimental data for water and it showed good results. (author)

  13. General arrangement design optimization of emergency response facility (TSC, OSC) in Korea next generation reactor (APR-1400)

    International Nuclear Information System (INIS)

    The accident at the Three Mile Island (TMI) led to install some data processing and display equipment to assist control room personnel in rapidly evaluating the safety status. And also to place in the plant for providing operators with technical support and an emergency response center for radiological environmental assessments and determination of recommended public protective action during emergency. In practice, most of the countries possessing nuclear power plants including USA have partially or wholly adopted US NRC regulations and guidelines for Emergency Response Facility(ERF). Also the Korea nuclear power plants are implementing or operating ERF and SPDS after analyzing US NRC regulations and guideline since TMI accident. So this paper first been reviewed Korea Regulations, US NRC published codes and standards related to ERF (TSC/OSC). Finally this paper is described the design optimization of general arrangement in emergency response facility to improve emergency response capability in Korea Next Generation Reactor(APR-1400), which are best suitable for our domestic situation and also enhance the emergency response capability of ERF

  14. Discussion on RELAP5 and RETRAN3D Modeling for Passive Condensate Cooling Tank of Passive Auxiliary Feedwater System in APR+

    International Nuclear Information System (INIS)

    Domestic nuclear industry has started the development of APR+ as a Korean specific reactor for the export strategy. In the development of APR+ a passive auxiliary feedwater system (PAFS) has been considered as a noticeable candidate of improved design. The outline of PAFS and passive condensate cooling tank (PCCT) containing horizontal heat exchanger is shown in Fig. 1. For the successful design of PAFS, performance analyses or safety analyses are prerequisite using best estimate thermal hydraulic codes such as RELAP5 or RETRAN3D. Because of the inherent features of RELAP5 or RETRAN3D, pool model and condensation in horizontal tube have not been well-setup nor widely studied. This paper discusses about the PCCT phenomena including steam condensation in horizontal tube and pool heat transfer, and RELAP5 and RETRAN3D modeling

  15. Facteurs influençant le retour au travail après transplantation chez 61 patients rénaux ou hépatiques

    OpenAIRE

    Praz-Christianaz S.-M.

    2014-01-01

    Enjeux La réussite d'une transplantation rénale ou hépatique intègre non seulement le succès de l'acte chirurgical et sa prise en charge médicale post-greffe, mais également pour le patient greffé l'assurance d'une nouvelle qualité de vie dont le retour au travail fait partie. Le retour au travail après greffe est cependant généralement peu étudié dans la littérature et peu discuté semble-t-il au niveau médical que ce soit avant ou après greffe, quand bien même d'un point de vue médico-socio-...

  16. Une première consultation après la crise de décembre 2007Les élections partielles du 11 juin 2008

    OpenAIRE

    Cussac, Anne

    2008-01-01

    Après les élections générales du 27 décembre 2007, les Kenyans, dans certaines circonscriptions électorales ont denouveau été appelés aux urnes le 11 juin 2008, pour élire cinq députés et une cinquantaine de représentantslocaux. Ces élections partielles, qui se déroulées dans les circonscriptions d’Ainamoi, Emuhaya, Embakasi1, Kilgoris etWajir North, ont constitué la toute première consultation après la formation du gouvernement de grande coalition entrele Party of National Unity (PNU) du Pré...

  17. Mu dX, a derivative of Mu d1 (lac Apr) which makes stable lacZ fusions at high temperature.

    OpenAIRE

    Baker, T A; Howe, M M; Gross, C A

    1983-01-01

    We describe defective Mu phage Mu dX (Mu d1 Bx::Tn9 [lac Apr Cmr]) which is useful for insertion mutagenesis and for construction of lac operon fusions in vivo. Mu dX retains the insertion properties of Mu d1 but produces temperature-resistant lysogens and transposes at a reduced frequency. A method is described to convert existing Mu d1 insertions to Mu dX.

  18. Antiviral activity of the plant extracts from Thuja orientalis, Aster spathulifolius, and Pinus thunbergii against influenza virus A/PR/8/34.

    Science.gov (United States)

    Won, Ji-Na; Lee, Seo-Yong; Song, Dae-sub; Poo, Haryoung

    2013-01-01

    Influenza viruses cause significant morbidity and mortality in humans through epidemics or pandemics. Currently, two classes of anti-influenza virus drugs, M2 ion-channel inhibitors (amantadin and rimantadine) and neuraminidase inhibitors (oseltamivir and zanamivir), have been used for the treatment of the influenza virus infection. Since the resistance to these drugs has been reported, the development of a new antiviral agent is necessary. In this study, we examined the antiviral efficacy of the plant extracts against the influenza A/PR/8/34 infection. In vitro, the antiviral activities of the plant extracts were investigated using the cell-based screening. Three plant extracts, Thuja orientalis, Aster spathulifolius, and Pinus thunbergii, were shown to induce a high cell viability rate after the infection with the influenza A/PR/8/34 virus. The antiviral activity of the plant extracts also increased as a function of the concentration of the extracts and these extracts significantly reduced the visible cytopathic effect caused by virus infections. Furthermore, the treatment with T. orientalis was shown to have a stronger inhibitory effect than that with A. spathulifolius or P. thunbergii. These results may suggest that T. orientalis has anti-influenza A/PR/8/34 activity. PMID:23314378

  19. Development of a Phenomena Identification Ranking Table (PIRT) for a Station Black Out (SBO) Accident of the APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Kyoung Ho; Yun, Byong Jo; Sim, Suk Ku and others

    2013-10-15

    SBO is one of the most important DEC in that without any proper operator actions, a total loss of heat sink leads to core uncover, to core damage, and ultimately a core melt-down scenario under high pressure. Due to this safety importance, SBO is considered to be a base test item of the OECD-ATLAS project. In this study, Phenomena Identification Ranking Table (PIRT) has been developed for identifying the major parameters affecting the thermal-hydraulic phenomena in SBO transients. Development of PIRT for SBO transient is expected to contribute to making strategy for performing a thermal-hydraulic integral effect test with ATLAS which includes determination of proper test conditions and improvement of measurements. The PIRT process used in this study follows the methodology previously applied in the Passive Auxiliary Feedwater System (PAFS) of the APR+ (Advanced Power Reactor Plus). The PIRT has been developed for identifying the major parameters affecting the thermal-hydraulic phenomena during a SBO transient. The PSC was determined to be the core mixture level from the expert panel discussion. As for the major components of the nuclear power plant, the rank of the importance and the knowledge level were summarized for each of the three temporal phases. Taking into account the important phenomena from the PIRT result, it can be confirmed that ATLAS has a capability of simulating the major thermal-hydraulic phenomena during a SBO transient as realistically as possible. The present PIRT is expected to contribute to making strategy for performing a thermal-hydraulic integral effect test with ATLAS in the framework of the OECD-ATLAS project.

  20. Bioréacteur à membranes immergées pour le traitement d’eaux usées domestiques. Influence des conditions de filtration et de l’hydrodynamique sur les performances du procédé.

    OpenAIRE

    Van Kaam, Romuald

    2005-01-01

    Le travail présenté dans ce mémoire est focalisé sur la compréhension de l’action des paramètres de filtration (temps de filtration, de non filtration, de rétrolavage, mode et débit d’aération) dans un BAMI pour le traitement d’eaux usées domestiques. La partie expérimentale a été conduite en deux temps. Tout d’abord sur effluent synthétique pour tester différentes conditions opératoires de filtration dans des conditions biologiques maîtrisées puis sur effluent domestique afin de valider les ...

  1. Binary analysis: 1. part: definitions and treatment of binary functions; 2. part: applications and functions of trans-coding; Analyse binaire: 1ere partie: definitions et traitements des fonctions binaires; 2eme partie: applications et fonctions de transcodage

    Energy Technology Data Exchange (ETDEWEB)

    Vallee, R.L. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1968-07-01

    The study of binary groups under their mathematical aspects constitutes the matter of binary analysis, the purpose of which consists in developing altogether simple, rigorous and practical methods needed by the technicians, the engineers and all those who may be mainly concerned by digital processing. This subject, fast extending if not determining, however tends actually to play a main part in nuclear electronics as well as in several other research areas. (authors) [French] L'analyse binaire a pour objet l'etude mathematique des proprietes d'ensembles binaires algebriques et pour but l'elaboration de methodes simples, rigoureuses et pratiques, destinees aux techniciens, aux ingenieurs et a tous ceux qu'interesse directement le traitement numerique de l'information, discipline en expansion rapide qui, deja, en electronique nucleaire comme dans de nombreux autres domaines de la recherche, tend a jouer un role essentiel sinon determinant. (auteurs)

  2. Contributions au traitement des incertitudes en modélisation numérique : propagation d'ondes en milieu aléatoire et analyse statistique d'expériences simulées

    OpenAIRE

    Iooss, Bertrand

    2009-01-01

    Le présent document constitue mon mémoire d'habilitation à diriger des recherches. Il retrace mon activité scientifique de ces douze dernières années, depuis ma thèse jusqu'aux travaux réalisés en tant qu'ingénieur-chercheur du CEA Cadarache. Les deux chapitres qui structurent ce document correspondent à deux domaines de recherche relativement différents mais se référant tous les deux au traitement des incertitudes dans des problèmes d'ingénierie. Le premier chapitre établit une synthèse de m...

  3. Comment trouver et mettre en pratique clinique les données actuelles de la science ? : application au traitement des infections urinaires et pulmonaires du patient âgé

    OpenAIRE

    Lutters, Monika

    2001-01-01

    Une évaluation critique des articles de revue sur les infections de la personne âgée a montré que ceux-ci sont de faible qualité méthodologique et difficilement applicables en pratique clinique. Une comparaison de quatre moteurs de recherche de la base de données MEDLINE a mis en évidence de grandes différences inexplicables du taux d'articles identifiés. Une revue systématique sur la durée de traitement dans les infections urinaires basses non compliquées de la femme âgée a révélé que l'on n...

  4. Comment trouver et mettre en pratique clinique les données actuelles de la science ?: application au traitement des infections urinaires et pulmonaires du patient âgé

    OpenAIRE

    Lutters, Monika; Dayer, Pierre; Vogt, Nicole

    2004-01-01

    Une évaluation critique des articles de revue sur les infections de la personne âgée a montré que ceux-ci sont de faible qualité méthodologique et difficilement applicables en pratique clinique. Une comparaison de quatre moteurs de recherche de la base de données MEDLINE a mis en évidence de grandes différences inexplicables du taux d'articles identifiés. Une revue systématique sur la durée de traitement dans les infections urinaires basses non compliquées de la femme âgée a révélé que l'on n...

  5. Traitement de données dans les groupes de Lie : une approche algébrique. Application au recalage non-linéaire et à l'imagerie du tenseur de diffusion

    OpenAIRE

    Arsigny, Vincent

    2006-01-01

    Ces dernières années, le besoin de cadres rigoureux pour traiter des données non-linéaires s'est développé considérablement en imagerie médicale. Ici, nous avons proposé plusieurs cadres généraux pour traiter certains de ces types de données, qui appartiennent à des groupes de Lie. Pour ce faire, nous nous sommes appuyés sur les propriétés algébriques de ces espaces. Ainsi, nous avons présenté un cadre de traitement général pour les matrices symétriques définies positives, appelé log-euclidie...

  6. Fabrication de transistors mono-electroniques en silicium pour le traitement classique et quantique de l'information: une approche nanodamascene

    Science.gov (United States)

    Harvey-Collard, Patrick

    Les transistors mono-electroniques (SETs) sont des dispositifs ayant un grand potentiel d'applications, comme la detection de charge ultra-sensible, la logique a basse consommation de puissance, la memoire ou la metrologie. De plus, la possibilite de pieger un seul electron et de manipuler son etat de spin pourrait permettre des applications en informatique quantique. Le silicium est un materiau interessant pour fabriquer l'ilot d'un SET. Son gap semi-conducteur permet le fonctionnement du dispositif dans le regime a un seul electron ou trou et pourrait permettre d'etendre la plage d'operation du SET en temperature en augmentant l'energie d'addition du diamant central de la valeur du gap. En outre, le silicium beneficie de plus de quarante annees d'expertise en microfabrication et d'une compatibilite avec la technologie metal--oxyde--semi-conducteur complementaire (CMOS). Cependant, la fabrication de ces dispositifs fait face a de serieuses limitations a cause de la taille nanometrique requise pour l'ilot. A ce jour, les procedes de fabrication proposes permettant l'operation a la temperature ambiante sont trop peu reproductibles pour permettre des applications a grande echelle. Dans ce memoire de maitrise, la fabrication de transistors mono-electroniques en silicium (Si-SETs) pour le traitement classique et quantique de l'information est realisee avec un procede nanodamascene. Le polissage chimico-mecanique (CMP) est introduit comme etape clef de la fabrication du transistor, permettant le controle au nanometre pres (nanodamascene) de l'epaisseur du transistor. Cet outil permet la fabrication de dispositifs ayant une geometrie auparavant impossible a realiser et ouvre la porte a l'innovation technologique. De plus, un procede de gravure du silicium par plasma a couplage inductif (ICP) est developpe pour permettre la fabrication de nanostructures de silicium sur une nanotopographie alliant le nano et le 3D. Les Si-SETs fabriques sont caracterises a basse

  7. La métaplasie osteoide de l'endomètre après une grossesse à terme: à propos d'un cas rare

    Science.gov (United States)

    Jayi, Sofia; Bouguern, Hakima; Fatemi, Hind; Chaara, Hikmat; Laamarti, Afaf; Melhouf, Aabdelilah

    2013-01-01

    La métaplasie ostéoïde de l'endomètre (MOE) est une entité rare correspondant à la présence de tissu osseux dans l'endomètre, elle est le plus souvent diagnostiquée dans un contexte d'infertilité secondaire faisant suite à une grossesse interrompue. Même si plusieurs facteurs de risque sont répertoriés, sa physiopathologie reste mal connue et sa traduction clinique est très variable. Nous rapportons un cas de MOE apparu suite à un curetage pour rétention placentaire en post-partum. Le diagnostic a été suspecté par l'hystéroscopie et confirmé par l’étude anatomopathologique. A notre connaissance c'est le premier cas décrit suite à un accouchement à terme. A travers notre cas et à la lumière d'une revue de la littérature nous insistons sur les caractéristiques épidémiologiques, physiopathologiques, cliniques et para cliniques de cette entité rare, dont la connaissance est primordiale pour un diagnostic sûr et par conséquent un traitement adapté permettant souvent de récupérer la fertilité de la patiente. PMID:23898363

  8. PRIMA-1Met/APR-246 induces apoptosis and tumor growth delay in small cell lung cancer expressing mutant p53

    DEFF Research Database (Denmark)

    Zandi, Roza; Selivanova, Galina; Christensen, Camilla Laulund;

    2011-01-01

    Small cell lung cancer (SCLC) is a highly malignant disease with poor prognosis, necessitating the need to develop new and efficient treatment modalities. PRIMA-1(Met) (p53-dependent reactivation of massive apoptosis), also known as APR-246, is a small molecule, which restores tumor suppressor...... function to mutant p53 and induces cancer cell death in various cancer types. Since p53 is mutated in more than 90% of SCLC, we investigated the ability of PRIMA-1(Met) to induce apoptosis and inhibit tumor growth in SCLC with different p53 mutations....

  9. Performances, modélisation et limites d'un procédé à lit fluidisé associant culture libre et fixée (IFAS) pour le traitement du carbone et de l'azote des eaux résiduaires

    OpenAIRE

    Moretti, Paul

    2015-01-01

    Motivées par des normes de rejets en azote toujours plus sévères et par les besoins d'extension de certaines stations d'épuration, les agglomérations sont à la recherche de nouvelles technologies de traitement plus compactes et plus performantes. Dans ce sens, le procédé hybride, à lit fluidisé placé dans un réacteur de type boues activées (IFAS), est une nouvelle technologie de traitement du carbone et de l'azote très attractive. L'objectif de cette thèse est d'optimiser le dimensionnement d...

  10. Contribution à la mise au point d'une démarche rationnelle de sélection des traitements de surface :illustration dans le cas des dispositifs de fonderie de l'aluminium. Contribution to a comprehensive selection of surface treatments: the case of aluminium foundry devices.

    OpenAIRE

    D'Ans, Pierre

    2009-01-01

    Sélectionner des traitements de surface pour l’industrie nécessite de prendre en compte :les propriétés à conférer au substrat, la nature et la géométrie de celui-ci et les caractéristiques du milieu extérieur. Certaines combinaisons de ces paramètres rendent difficile la sélection d’un traitement unique, d’où le recours à des multitraitements de surface. Dès lors, se posent les questions suivantes :- Utiliser des multitraitements de surface peut se faire en scindant les différentes requêtes ...

  11. Recovery and radio-resistance in mice after external irradiation; Restauration et radio-resistance chez la souris apres irradiation externe

    Energy Technology Data Exchange (ETDEWEB)

    Le Guillou, S. [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1965-07-01

    The author presents a literature study concerning recovery from external irradiation and an analysis of experimental data (which appear to suggest the idea of a radio-resistance in animals), as well as the hypotheses put forward for explaining this phenomenon. The author then describes an experiment carried out on mice whose LD 50/30 days increased from 1005 to 1380 rads and for which it was shown that an increase occurs in the number of certain anti-bodies circulating after a low dose of {gamma} irradiation. (author) [French] L'auteur presente une etude bibliographique de la restauration apres irradiation externe et une analyse des donnees experimentales qui paraissent suggerer la notion de radioresistance chez les animaux ainsi que les hypotheses cherchant a expliquer ce phenomene. Il relate ensuite une experience realisee sur des souris dont la DL 50/30 jours est passee de 1005 a 1380 rads et dans laquelle est montree l'augmentation de certains anticorps circulant apres une faible dose d'irradiation gamma. (auteur)

  12. Une installation expérimentale pour l'étude du traitement par combustion des fumées industrielles An Experimental Plant for Processing Industrial Fumes by Combustion

    Directory of Open Access Journals (Sweden)

    Morillon R.

    2006-11-01

    Full Text Available Le rejet à l'atmosphère d'effluents gazeux d'origine industrielle entraîne un accroissement sensible de la pollution atmosphérique ; en outre, il s'accompagne souvent d'une perte d'énergie lorsque l'élément polluant est un hydrocarbure. Dans ce cas, l'utilisation du gaz naturel pour le traitement par combustion des fumées industrielles apporte une solution élégante et souvent peu coûteuse grâce à la récupération d'énergie qu'il est possible de faire. La première partie de l'article rappelle les aspects théoriques de ce traitement ; en particulier, l'influence des divers éléments sur son efficacité y est discutée (composition de l'atmosphère polluée, température, temps de séjour, etc.. II apparaît ainsi que diverses conditions doivent être remplies simultanément pour obtenir une efficacité satisfaisante. Afin de disposer d'éléments d'ingénierie permettant de construire les unités de traitement les plus efficaces et les plus sûres possible, au coût le plus bas possible, la Direction des études et techniques nouvelles du Gaz de France a réalisé une installation expérimentale qui est présentée dans la deuxième partie de l'article. Enfin, quelques examples d'utilisation de cette installation expérimentale, qui constitue un nouvel outil de travail mis à la disposition des utisitateurs et des constructeurs, sont décrits dans la troisième partie de l'article. The discharge into the atmosphere of industrial waste gases causes substantially increased air pollution. Moreover, it is often accompanied by loss of energy when the polluting element is a hydrocarbon. In such cases, the use of natural gas for processing industrial fumes by combustion provides an elegant solution, which moy often prove economical too becouse of the recovery of energy it makes possible. The first part of this article reviews the theoretical aspects of such processing. The way in which its effectiveness is affected by various parameters

  13. Cinétique de la troponine Ic et valeurs seuils pour le diagnostic d'infarctus du myocarde après chirurgie cardiaque sous circulation extracorporelle

    Science.gov (United States)

    Kallel, Samy; Jarraya, Anwar; Ellouze, Maged; Frikha, Imed; Karoui, Abbdelhamid

    2012-01-01

    Introduction L'objectif de ce travail était d’étudier la cinétique de la Troponine Ic (TnIc) après chirurgie cardiaque sous circulation extracorporelle (CEC) et établir des valeurs seuils de TnIc pour le diagnostic d'infarctus du myocarde (IDM) post opératoire. Il s'agissait d'une étude prospective type cohorte observationnelle. Méthodes Nous avons inclus 37 patients âgés de plus de 18 ans proposés pour chirurgie valvulaire ou pontage aorto coronarien sous CEC. Nous avons suivi la cinétique de TnIc par des dosages immunoenzymatique sur mini-vidas® avant et après la CEC, à H4 et H12 postopératoire puis tous les jours les 4 premiers jours. Le cutoff pour le diagnostic d'IDM post opératoire a été défini comme la valeur moyenne de troponine + deux déviations standards des patients indemnes de complications cardiaques. Résultats Les valeurs de TnIc en préopératoire étaient toutes inférieures au seuil de détection de la méthode de dosage (<0,01µg/l). Les valeurs de TnIc augmentent en postopératoire immédiat pour atteindre un maximum à H4 puis diminuent progressivement pour se normaliser après 4 à 5 jours. Les valeurs seuils ont été déterminées pour H0, H4,H12, H24, H48, H72, H96 et ont été respectivement 1.36, 2.58, 3.1, 3.23, 2.13, 1.53, 1.17 pour la chirurgie coronaire et 3.75, 5.39, 4.22, 3.41, 1.65, 1.3 1.19 pour la chirurgie valvulaire. Conclusion La connaissance de la cinétique de TnIc lors de chirurgie cardiaque non compliquée et la fixation de valeur seuil ou Cutoff permet aux cliniciens de distinguer entre dommage myocardique secondaire à la chirurgie et IDM. PMID:23396754

  14. Prévalence, facteurs associés et prédisposant au syndrome métabolique chez les personnes vivants avec le VIH sous traitement antirétroviral à Porto-Novo en 2014

    Science.gov (United States)

    Adébayo, Alassani; Albert, Dovonou Comlan; Ericie, Sossou; Angelo, Attinsounon Cossi; Jules, Gninkoun; Armand, Wanvoegbe; Séraphin, Ahoui; Léopold, Codjo; Gabriel, Ade

    2015-01-01

    Introduction Le syndrome métabolique est associé aux maladies cardiovasculaires. L'infection au VIH est devenue aujourd'hui une maladie chronique. L'objectif de cette étude est de déterminer la prévalence, les facteurs associés et prédisposant au syndrome métabolique chez les patients infectés par le VIH sous traitement antirétroviral. Méthodes Il s'est agi d'une étude transversale, descriptive et analytique. La population d’étude est constituée des patients vivant avec le VIH sous antirétroviral suivis au Centre Hospitalier Universitaire de l'Ouémé-Plateau. Le syndrome métabolique a été défini selon les critères de la Fédération Internationale du Diabète. Résultats La population était constituée de 244 patients. La prévalence du syndrome métabolique était de 18,03% avec une prédominance féminine (74,6%). La moyenne d’âge était de 40,7 ± 9,71 ans. Les facteurs associés au syndrome métabolique étaient le sexe féminin, la sédentarité, l'antécédent d'HTA, le surpoids, l'apport énergétique élevé, l'apport lipidique élevé, la consommation d'alcool, la consommation de tabac et l'hypercholestérolémie. Les facteurs prédisposant au syndrome métabolique étaient la présence de l'HTA, le tour de taille élevé, l'hyperglycémie, l'hypocholestérolémie HDL et l'hypertriglycéridémie. Conclusion Le syndrome métabolique est fréquent chez les patients infectés par le VIH sous traitement antirétroviral. Une prévention prenant en compte les facteurs associés et prédisposant s'avère nécessaire. PMID:26966492

  15. Truman, "faith-based" diplomatie et ambigüités du Plan Marshall : cas de la France de l'après-guerre

    OpenAIRE

    Autran, Jean-Marie

    2015-01-01

    La "Faith-based" diplomatie américaine et les ambiguïtés du plan Marshall : le cas de la France dans l’après-guerre. Le Président Harry S. Truman (1945-1953) affirme dès 1946 que les E.U. doivent s’armer d'une « diplomatie fondée sur la foi » pour encourager la reconstruction spirituelle d'une Europe « déchristianisée » face au communisme. Pour faire barrage au marxisme de l’Union Soviétique, il fallait commencer par la France, vue comme la pierre de voûte spirituelle. Plus que toute autre na...

  16. Cinétique de la troponine Ic et valeurs seuils pour le diagnostic d'infarctus du myocarde après chirurgie cardiaque sous circulation extracorporelle

    OpenAIRE

    Kallel, Samy; Jarraya, Anwar; Ellouze, Maged; Frikha, Imed; Karoui, Abbdelhamid

    2012-01-01

    Introduction L'objectif de ce travail était d’étudier la cinétique de la Troponine Ic (TnIc) après chirurgie cardiaque sous circulation extracorporelle (CEC) et établir des valeurs seuils de TnIc pour le diagnostic d'infarctus du myocarde (IDM) post opératoire. Il s'agissait d'une étude prospective type cohorte observationnelle. Méthodes Nous avons inclus 37 patients âgés de plus de 18 ans proposés pour chirurgie valvulaire ou pontage aorto coronarien sous CEC. Nous avons suivi la cinétique d...

  17. Development of a Prototypical Condensation Model for the Nearly Horizontal Heat Exchanger Tube of the APR+ PAFS(Passive Auxiliary Feed-water System)

    Energy Technology Data Exchange (ETDEWEB)

    Ahn, Tae Hwan; Yun, Byong Jo; Jeong, Jae Jun [Pusan National Univ., Busan (Korea, Republic of)

    2013-10-15

    In this study, a new condensation heat transfer model was developed for the separated flow regime in the nearly horizontal tube. A new heat transfer model which takes into account of different heat transfer mechanisms occurred in the upper and lower regions of perimeters was developed in the nearly horizontal tube. The present model shows good prediction capability against experimental data. Passive Auxiliary Feed-water System(PAFS) which is adopted in the Korean advanced nuclear power plant, APR+, removes decay heat by condensing steam from the secondary side in the nearly horizontal tubes under the accident condition. The comparison of prediction against PASCAL(2011) experimental data obtained by KAERI indicated that the best estimated safety analysis code such as MARS tends to underestimate the condensation heat transfer coefficient.

  18. Development of a Prototypical Condensation Model for the Nearly Horizontal Heat Exchanger Tube of the APR+ PAFS(Passive Auxiliary Feed-water System)

    International Nuclear Information System (INIS)

    In this study, a new condensation heat transfer model was developed for the separated flow regime in the nearly horizontal tube. A new heat transfer model which takes into account of different heat transfer mechanisms occurred in the upper and lower regions of perimeters was developed in the nearly horizontal tube. The present model shows good prediction capability against experimental data. Passive Auxiliary Feed-water System(PAFS) which is adopted in the Korean advanced nuclear power plant, APR+, removes decay heat by condensing steam from the secondary side in the nearly horizontal tubes under the accident condition. The comparison of prediction against PASCAL(2011) experimental data obtained by KAERI indicated that the best estimated safety analysis code such as MARS tends to underestimate the condensation heat transfer coefficient

  19. La présence des Nabatéens en Italie (ier siècle av.-iie siècle apr. J.-C.)

    OpenAIRE

    Schwentzel, Christian-Georges

    2015-01-01

    La présence des Nabatéens en Italie est attestée par plusieurs documents épigraphiques ainsi que par quelques monuments découverts à Pouzzoles : des autels et des objets de culte, des sculptures. Cette présence s’est sans doute développée à la fin du iie s. av. J.-C., ou au début du ier siècle av. J.-C., avant de s’effacer, probablement au iie siècle apr. J.-C. En tout cas, les documents épigraphiques mentionnant la présence de Nabatéens en Italie sont datés des règnes de Malichos Ier (58-30 ...

  20. The LasB Elastase of Pseudomonas aeruginosa Acts in Concert with Alkaline Protease AprA To Prevent Flagellin-Mediated Immune Recognition.

    Science.gov (United States)

    Casilag, Fiordiligie; Lorenz, Anne; Krueger, Jonas; Klawonn, Frank; Weiss, Siegfried; Häussler, Susanne

    2016-01-01

    The opportunistic pathogen Pseudomonas aeruginosa is capable of establishing severe and persistent infections in various eukaryotic hosts. It encodes a wide array of virulence factors and employs several strategies to evade immune detection. In the present study, we screened the Harvard Medical School transposon mutant library of P. aeruginosa PA14 for bacterial factors that modulate interleukin-8 responses in A549 human airway epithelial cells. We found that in addition to the previously identified alkaline protease AprA, the elastase LasB is capable of degrading exogenous flagellin under calcium-replete conditions and prevents flagellin-mediated immune recognition. Our results indicate that the production of two proteases with anti-flagellin activity provides a failsafe mechanism for P. aeruginosa to ensure the maintenance of protease-dependent immune-modulating functions. PMID:26502908

  1. Modele de simulation de la duree d'humectation des feuilles au champ apres une pluie. Cas d'un couvert homogene

    OpenAIRE

    Huber, L.

    1988-01-01

    La présence d’eau libre à la surface des organes végétaux pendant un temps minimal est un facteur essentiel lors de la contamination de la plante-hôte par un champignon. Afin de prévoir l’occurrence de ce phénomène en terme de durée, un modèle multi-couches de transfert de masse et d’énergie est adapté au cas de la simulation de la durée d’humectation des feuilles après une pluie au sein d’un couvert végétal homogène. Le but est de spatialiser ce paramètre intéressant les phytopathologis...

  2. Facteurs prédictifs d'une intolérance au glucose après un diabète gestationnel

    OpenAIRE

    Guillermin-Spahr, Marie-Luce

    2004-01-01

    Les critères permettant de prédire la persistance d'une IG après un diabète gestationnel sont insuffisants. Nous avons analysé les caractéristiques ante- et post partum (PP) de 239 femmes avec diabète gestationnel. Les résultats de l'hyperglycémie provoquée (HGPO) 6 semaines post partum étaient: 51% normal; 15% IG; 11% diabète vrai; et 23% IG non diagnostique. Des 42 femmes diagnostiquées précocement (< 24ème semaine), 23% avaient un test normal, et 40% avaient un diabète persistant. Les fact...

  3. Facteurs prédictifs d'une intolérance au glucose après un diabète gestationnel

    OpenAIRE

    Guillermin-Spahr, Marie-Luce; Golay, Alain

    2005-01-01

    Les critères permettant de prédire la persistance d'une IG après un diabète gestationnel sont insuffisants. Nous avons analysé les caractéristiques ante- et post partum (PP) de 239 femmes avec diabète gestationnel. Les résultats de l'hyperglycémie provoquée (HGPO) 6 semaines post partum étaient: 51% normal; 15% IG; 11% diabète vrai; et 23% IG non diagnostique. Des 42 femmes diagnostiquées précocement (< 24ème semaine), 23% avaient un test normal, et 40% avaient un diabète persistant. Les fact...

  4. Best Estimate Thermal-Hydraulic System Analysis using the MARS Code for the Steam Generator Tube Rupture Accident in the APR1400

    International Nuclear Information System (INIS)

    A postulated SGTR (Steam Generator Tube Rupture) accident of the APR1400 was analysed using the best estimate safety analysis code, MARS (Multidimensional Analysis of Reactor Safety). The SGTR accident is one of the design basis accidents, which has a unique feature of the penetration of the barrier between the reactor coolant system (RCS) and the secondary system resulting from the failure of a steam generator U-tube. The SGTR has an importance in safety due to a concern of a containment bypass of radioactive inventory. In the course of the SGTR, the radioactivity leaking from a broken steam generator Utube mixes with the shell-side water in an affected steam generator. Leak flow from ruptured U-tubes can increase a water level and a pressure of the affected steam generator. Following a reactor trip and a turbine trip, the main steam safety valves (MSSVs) can be open to mitigate an increase in the secondary system pressure. Meanwhile, the SGTR can provide a direct flow path from the primary to the secondary system resulting in the release of fission products into the atmosphere. As one of the most limiting SGTR accidents, a leak flow equivalent to a double-ended rupture of five Utubes was analysed in this study. The main objective of this study is not only to provide physical insight into the system response of the APR1400 reactor during a SGTR but also to investigate the effect of reactor trip type of the HSGL (High Steam Generator Level) trip and the LPP (Low Pressurizer Pressure) trip on the thermal-hydraulic system response

  5. Les éducateurs de la Protection judiciaire de la jeunesse à l’épreuve de l’évolution du traitement pénal des jeunes délinquants

    Directory of Open Access Journals (Sweden)

    Nicolas Sallée

    2010-02-01

    Full Text Available Le présent article propose une généalogie de la profession d’éducateur de la Protection judiciaire de la jeunesse, qui interroge les transformations de ce groupe professionnel. À partir d’un questionnement sur la culture professionnelle des éducateurs, nous étudierons la manière dont la profession réagit aux évolutions récentes du traitement pénal des jeunes délinquants. Pour cela, nous considèrerons les cadres de l’action des éducateurs, à la jonction des constructions savantes de la délinquance juvénile, des débats sociaux sur les manières de la traiter et de l’état des structures institutionnelles destinées à l’endiguer.A genealogical approach is used to investigate the evolution of the profession of the Legal Youth Protection’s youth workers. By questioning the professional culture of youth workers, the aim of this article is to analyse the response of the profession to the evolution of penal juvenile justice. The frames of youth worker’s practices are tackled at the threefold intersection of the scientific constructions of juvenile delinquency, the social debates on the way to sort it out, and the state of the organisations that intend to contain this juvenile delinquency.

  6. Precificação de consultoria empresarial com a contribuição das estratégias de apreçamento = Entrepreneurial Counseling Pricing with Pricing Strategy Contribution

    Directory of Open Access Journals (Sweden)

    Nivaldo João dos Santos

    2008-11-01

    Full Text Available A precificação de serviços de consultoria também pode se beneficiar dos conceitos e idéias das estratégias de apreçamento de bens de consumo de massa, especificamente na área de consultoria de gestão empresarial. Apesar deste campo ser dominado por grandes corporações multinacionais, ainda existe espaço para empresas e profissionais nacionais. Por se tratar de mercado que envolve valores de grande magnitude, imaginasse que as instituições de sucesso adotem estratégia de apreçamento. Neste trabalho, estratégias de apreçamento foram selecionadas para exame e verificação de aplicabilidade quando do estabelecimento valor pelos serviços da consultoria de gestão empresarial. O apreçamento de desnatação, apreçamento de penetração, apreçamento neutro e apreçamento baseado em valor tiveram seus conceitos sintetizados para fins de verificação. O apreçamento baseado em valor se revelou o mais propício para este tipo de produto (consultoria e o processo de comunicação é o elemento crítico para evidenciar valor, benefícios e, finalmente, justificar o preço do serviço. A sugestão de roteiro para apreçamento de serviço de consultoria empresarial é apresentada ao final, como resultado da análise das diversas estratégias de apreçamento.The pricing of counseling services may also benefit from strategy concepts and ideas ofmass consumption goods pricing, specifically within the entrepreneurial managementcounseling area. Even though this field has been taken over by big multinationalcorporations, there is still some space for national enterprisings and professionals. As itis a market that involves values of great magnitude, it is thought that successfulinstitutions adopt this pricing strategy. In this study, pricing strategies were selectedfor analysis and applicability checking by the time the price for entrepreneurialmanagement counseling service was established. The skimming pricing, penetratingpricing, neutral

  7. Optimisation de la conservation des cosmétiques : impact de la formulation, recherche de nouveaux conservateurs naturels, encapsulation

    OpenAIRE

    Kerdudo, Audrey,

    2014-01-01

    Looking for innovation, cosmetic industry used even more new materials. Natural products are specially used. Our study evaluated the impact of cosmetic formulations on microbial developments. Then, a natural antimicrobial ingredient for cosmetics was developed. One vegetal extract was particulary studied. It was optimized for an easy introduction in cosmetic products. Antimicrobial activity of the natural extract was confirmed with challenge test. As some metabolites of the interesting extrac...

  8. A Study on Scenario Selection for Evaluation of Fission Product Behavior during a Severe Accident at APR 1400 Nuclear Power Plants

    International Nuclear Information System (INIS)

    As a part of an 'Evaluation of the State-of-the-Art on the Fission Product Behavior and Improvement of the Iodine Evaluation Model' Project, we at KINS plan to investigate source term behavior during a severe accident by MELCOR and to eventually compare it with results by RAIM which is an add-on code to MELCOR including iodine behavior model developed by KINS. Since species and amount of fission products in the containment depend on a specific accident, it is necessary to select accident scenarios for the study, especially taking account of its relative importance of occurrence or resultant effects for a specific plant. In this regard, we have reviewed U.S.NRC's Stateof- the-Art Reactor Consequence Analyses (SOARCA) and applied the SOARCA's method of scenario selection to Probabilistic Safety Assessment (PSA) for Shin-Kori 3·4 nuclear power plants which are APR1400 type reactors. Furthermore, we have selected scenarios from the PSA results with a new criterion in the light of risk, which consists of probability and consequence of accidents of interest. In this study, we have selected scenarios for evaluation of fission product behavior during a severe accident. Applying the U.S.NRC's SOARCA method to Shin-Kori 3·4 PSA revealed that it is practically useful to set a relative criterion for scenario studies since making a definite criterion as in SOARCA requires to consider many spatiotemporal factors such as regulation policies and safety technologies. With this in mind, the relative criterion of the scenario selection has been created using release frequency and release fraction of source term in the respect of risk from APR 1400 type Shin-Kori 3·4 Level 2 PSA. The selected representing scenarios are ISLOCA, SGTR, and SBO. A preliminary analysis has been tried for a SBO sequence with more severe and simple assumptions using MELCOR. The results show early release of volatile elements in the containment

  9. A Study on Scenario Selection for Evaluation of Fission Product Behavior during a Severe Accident at APR 1400 Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, E. S.; Kim, Han-Chul [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of); Cho, Song-Won [NSETec, Daejeon (Korea, Republic of)

    2015-05-15

    As a part of an 'Evaluation of the State-of-the-Art on the Fission Product Behavior and Improvement of the Iodine Evaluation Model' Project, we at KINS plan to investigate source term behavior during a severe accident by MELCOR and to eventually compare it with results by RAIM which is an add-on code to MELCOR including iodine behavior model developed by KINS. Since species and amount of fission products in the containment depend on a specific accident, it is necessary to select accident scenarios for the study, especially taking account of its relative importance of occurrence or resultant effects for a specific plant. In this regard, we have reviewed U.S.NRC's Stateof- the-Art Reactor Consequence Analyses (SOARCA) and applied the SOARCA's method of scenario selection to Probabilistic Safety Assessment (PSA) for Shin-Kori 3·4 nuclear power plants which are APR1400 type reactors. Furthermore, we have selected scenarios from the PSA results with a new criterion in the light of risk, which consists of probability and consequence of accidents of interest. In this study, we have selected scenarios for evaluation of fission product behavior during a severe accident. Applying the U.S.NRC's SOARCA method to Shin-Kori 3·4 PSA revealed that it is practically useful to set a relative criterion for scenario studies since making a definite criterion as in SOARCA requires to consider many spatiotemporal factors such as regulation policies and safety technologies. With this in mind, the relative criterion of the scenario selection has been created using release frequency and release fraction of source term in the respect of risk from APR 1400 type Shin-Kori 3·4 Level 2 PSA. The selected representing scenarios are ISLOCA, SGTR, and SBO. A preliminary analysis has been tried for a SBO sequence with more severe and simple assumptions using MELCOR. The results show early release of volatile elements in the containment.

  10. Analysis of PAFS (Passive Auxiliary Feedwater System) horizontal heat exchanger in APR+ and the scale-up capability of experimental loop

    International Nuclear Information System (INIS)

    APR+ (Advanced Power Reactor Plus) is the next generation nuclear power plant in Korea. It adopts PAFS (Passive Auxiliary Feedwater System) on the secondary system. It can replace the conventional active system for auxiliary feedwater injection to the steam generator, and it enables the coolant to be supplied by a passive system. It cools down the secondary system by heat transfer at a horizontal U-tube in PCCT (Passive Condensation Cooling Tank). High pressure steam flow from the steam generator is condensed in the horizontal heat exchanger. The water in PCCT is maintained at an atmospheric pressure, so that boiling heat transfer at the outside wall of heat exchanger and natural convection occur in PCCT pool. The heat exchanger and PCCT is higher than the steam generator, so condensate can be drained and injected to feedwater system without any active system. This study aims at analyzing the heat removal capacity for the design of the horizontal heat exchanger in PAFS. To design the condensation heat exchanger in PAFS, and the two-phase flow phenomena in horizontal U-tube and were investigated by MARS (Multi-dimensional Analysis for Reactor Safety, a thermal hydraulic system analysis code) calculation. By benchmarking with NOKO experimental result, MARS code showed a reasonable capability to quantitatively predict the condensation in horizontal tube heat exchanger. For the design of PAFS heat exchanger in APR+, the calculation results proved to sufficiently remove the decay heat of 138 MW in total by the condensation heat transfer without any active auxiliary feedwater system during TLOFW (Total Loss of Feed Water) accident. In the analysis, the distribution of thermal equilibrium quality and local liquid fraction in the horizontal U-tube was also investigated. In order to experimentally investigate the condensation phenomena and natural convection in PAFS, a test loop with a single horizontal U-tube and PCCT is under construction at KAERI (Korea Atomic Energy

  11. Dynamique des micropolluants organiques au cours du traitement biologique de résidus solides. : Lien entre caractérisation du résidu, localisation des micropolluants organiques au sein des compartiments du résidu et processus (sorption, biodégradation)

    OpenAIRE

    Aemig, Quentin

    2014-01-01

    41 % des boues produites en Europe sont utilisées en agriculture. Elles contiennent des micropolluants organiques (μPO), composés toxiques et persistants, retrouvés à de faibles concentrations dans les milieux aquatiques mais ayant un fort impact environnemental. Lors du traitement biologique des boues, les μPO sont éliminés par sorption ou biodégradation pouvant diminuer leur impact environnemental. Dans cette thèse, le devenir couplé de la matière organique et des μPO lors de la méthanisati...

  12. The Eddith Thermolysis Process: a Ground-Breaking Solution for Clean Treatment of Wastes Le procédé de thermolyse EDDITh : une solution innovante pour un traitement propre des déchets

    Directory of Open Access Journals (Sweden)

    Martin G. H.

    2006-12-01

    Full Text Available The current regulations concerning atmospheric pollutant discharge by incinerators, and the determination of public authorities to do away with waste dumps as of the beginning of the next decade are leading to a heavy demand for new installations. Areas which still use the dump method will have to equip themselves with purpose-built plants, and incinerators built more than twenty years ago will in many cases have to make way for more efficient units which meet the requirements of the legislators. In all, more than 200 new installations should be erected within the next ten years in France alone. The market prospects are even greater in Europe as a whole, since the problem of waste disposal exists under very much the same conditions in neighbouring countries. Les réglementations en vigueur relatives aux rejets atmosphériques des incinérateurs et la volonté des pouvoirs publics de supprimer les décharges dès le début de la prochaine décennie conduisent à une forte demande en installations neuves. Les régions qui pratiquent encore la mise en décharge devront s'équiper d'usines de traitement ad hoc et les incinérateurs construits il y a plus d'une vingtaine d'années devront souvent céder la place à des unités plus performantes répondant aux exigences du législateur. Au total, plus de 200 installations nouvelles devraient voir le jour d'ici dix ans rien qu'en France. Les perspectives de marché sont encore plus grandes en Europe, puisque le problème de l'élimination des déchets se pose sensiblement dans les mêmes termes dans les pays voisins.

  13. Les types d’arguments dans le traitement du débat sur la crise des banlieues par la télévision Types of Arguments Used on TV in the French Suburban Crisis Debate

    Directory of Open Access Journals (Sweden)

    Anne Kalinic

    2008-09-01

    Full Text Available Les émeutes de novembre 2005 survenues dans les banlieues françaises ont suscité un débat médiatisé à propos des causes de la crise et des modes d’intervention pour sa résolution. A travers son traitement discursif, le journal télévisé configure un cadrage du débat dans lequel les prises de position des différents acteurs interviewés viennent s’opposer. L’analyse des arguments des discours cités se décomposera sur les trois niveaux proposés par P. Charaudeau : problématisation, positionnement et probation, en tenant compte de leur valeur - par exemple, éthique, pragmatique ou émotionnelle - afin de dégager les différentes stratégies à visée persuasive.The October and November 2005 riots of the French suburbs, following the death of two teenagers chased by the police, have kindled a debate in the media on the causes of the crisis and the means used to resolve it. By its treatment of the question, TV discourse frames this debate, in which the stands of the various interviewed actors are in conflict. The analysis of the quoted arguments is performed on the three levels described by P. Charaudeau: “problematizing”, positioning, proving, while considering their value—for example, ethical, pragmatical or emotional—in order to find out the different strategies meant at persuading.

  14. Le traitement de l’erreur et la notion de progression dans l’enseignement/apprentissage des langues Error processing and the notion of progression in foreign language teaching and learning

    Directory of Open Access Journals (Sweden)

    Elkouria Chiahou

    2011-08-01

    Full Text Available Cet article traite de la question de l’erreur dans l’enseignement/apprentissage des langues. Il tente d’apporter un regard nouveau sur la correction, son but et ses modalités d’application. La démarche proposée est celle d’un retour vers les théories afin de mieux appréhender le mécanisme de l’erreur. Certains concepts relatifs au traitement de l’erreur ont été répertoriés dans des outils pédagogiques que nous avons élaborés dans le but de faciliter la mise en place d’une recherche-action. Si la forme de ces outils a pour objectif de favoriser la compréhension de concepts théoriques, il n’en demeure pas moins que le but ultime est de revenir à la pratique pour l’améliorer, c’est pourquoi nous proposons quelques exemples de reprises pertinentes.The present contribution is about how to deal with error in second language teaching and learning. We aim at bringing a new light to the issue of feedback on learners’ production, its relevance and practical applications. Our reflection will be based on theoretical references in the field to ensure that the concept of error is adequately understood. Ideas related to error processing have been listed and incorporated in the tools we have devised in order to implement an action-research. However, even if they were built originally to help us understand the theory better, the ultimate aim of those tools is to contribute to improving feedback provided in the classroom. To that purpose, the reader will find examples of effective versus ineffective correction.

  15. Impaired epithelial differentiation of induced pluripotent stem cells from ectodermal dysplasia-related patients is rescued by the small compound APR-246/PRIMA-1MET.

    Science.gov (United States)

    Shalom-Feuerstein, Ruby; Serror, Laura; Aberdam, Edith; Müller, Franz-Josef; van Bokhoven, Hans; Wiman, Klas G; Zhou, Huiqing; Aberdam, Daniel; Petit, Isabelle

    2013-02-01

    Ectodermal dysplasia is a group of congenital syndromes affecting a variety of ectodermal derivatives. Among them, ectrodactyly, ectodermal dysplasia, and cleft lip/palate (EEC) syndrome is caused by single point mutations in the p63 gene, which controls epidermal development and homeostasis. Phenotypic defects of the EEC syndrome include skin defects and limbal stem-cell deficiency. In this study, we designed a unique cellular model that recapitulated major embryonic defects related to EEC. Fibroblasts from healthy donors and EEC patients carrying two different point mutations in the DNA binding domain of p63 were reprogrammed into induced pluripotent stem cell (iPSC) lines. EEC-iPSC from both patients showed early ectodermal commitment into K18(+) cells but failed to further differentiate into K14(+) cells (epidermis/limbus) or K3/K12(+) cells (corneal epithelium). APR-246 (PRIMA-1(MET)), a small compound that restores functionality of mutant p53 in human tumor cells, could revert corneal epithelial lineage commitment and reinstate a normal p63-related signaling pathway. This study illustrates the relevance of iPSC for p63 related disorders and paves the way for future therapy of EEC. PMID:23355677

  16. Development of a New Condensation Heat Transfer Model for the Nearly Horizontal Tube of the APR+ PAFS (Passive Auxiliary Feed-water System)

    International Nuclear Information System (INIS)

    Korea Atomic Energy Research Institute (KAERI) has recently conducted PASCAL experiment to confirm the performance of PAFS. From the work, it is founded that the condensation heat transfer coefficient predicted by best estimated safety analysis code MARS (Multi-dimensional Analysis of Reactor Safety) was underestimated compared to the experimental data. Shah correlation embedded in MARS code is the typical model using the empirical two-phase multiplier to determine condensation heat transfer coefficient for annular flow in the condensing tube. On the other hand, the PASCAL experiment indicated that a stratified-wavy flow generally tends to occur in the downward inclined tube of the condensation heat exchanger. Therefore, in order to improve the prediction capability of safety analysis codes for PAFS, the present study has proposed a new condensation heat transfer model package for the nearly horizontal tube, which determines mechanistically the local heat transfer coefficient based on the flow regimes. To enhance prediction capability of one-dimensional best estimated code MARS for the PAFS of the Korean 3.5 generation nuclear power plant APR+, a new condensation heat transfer model package has been developed. The model package consists of the one-dimensional separated model for the void fraction, a flow regime model based on wetted angle, and the condensation heat transfer correlations. The model package considers the inclination angle of the condensing tube and various flow regimes that are expected in the tube during condensation process

  17. Coseismic Dip Slip Distribution of the 1 Apr 2007 Solomon Islands Mw8.1 Earthquake from a Fully Bayesian Inversion

    Science.gov (United States)

    Chen, T.

    2009-12-01

    102 uplift and subsidence measurements over the southeastern end of the rupture zone from two field surveys shortly after 1 Apr 2007 Solomon Islands Earthquake provide a unique geodetic constraint in the following inversion of distributed slip. In the conventional inversion of geodetic data for spatial distribution of fault slip the solution is maintained by minimizing the second-order spatial derivative of slip and the smoothing parameter is often selected subjectively at the bend of the trade-off curve of misfit as a function of slip roughness. A fully Bayesian slip inversion method[Fukuda et al.,2008] is used to overcome the deficiency of selecting the smoothing parameter subjectively. The smoothing parameter is estimated with the distributed slip at the same time under a unified theoretical Bayesian framework. The joint posterior probability density function of distributed slip and smoothing parameter is formulated using Bayes’ theorem and sampled with Markov chain Monte Carlo method. I will apply this method to coseismic slip distribution associated with the 2007 Mw8.1 Solomon Islands earthquake and compare the results of this method with conventional method and the coseismic finite fault model of Furlong et al.[2009].

  18. Numerical Analysis of In-Vessel Retention using MARS-Ga for APR1400 under the Ga-based External Reactor Vessel Cooling

    International Nuclear Information System (INIS)

    To stabilize and terminate the severe accident through enhancing the coolability of the degraded core, this paper introduces an approach to avoid heat removal limit by replacing flooding material from the borated water to the liquid metal, gallium. The attractive properties such as the low melting point, high boiling point, and no reaction with water ensure that gallium can play an important role in nuclear safety as an alternative coolant in the gap between the vessel and the vessel insulation. The properties of liquid gallium compared to other materials are indicated. For the investigation on the effect of gallium for IVR-ERVCS, numerical simulation for severe accident in APR 1400 using MARS-LMR was performed. In this study, the numerical analysis of gallium-based IVR-ERVCS using MARS-LMR was performed. The range of temperature distribution in this system was considered as an important factor and then the possibility of ERVC using liquid gallium was confirmed. In addition, It will perform the sensitivity studies for the heat transfer area between liquid gallium and borated water to design the optimum ERVC using liquid gallium

  19. Development of a New Condensation Heat Transfer Model for the Nearly Horizontal Tube of the APR+ PAFS (Passive Auxiliary Feed-water System)

    Energy Technology Data Exchange (ETDEWEB)

    Ahn, Taehwan; Jeong, Jaejun; Yun, Byongjo [Pusan National Univ., Busan (Korea, Republic of); Kang, Kyongho; Park, Yusun [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Cheon, Jong [KHNP Central Research Institute, Daejeon (Korea, Republic of)

    2014-05-15

    Korea Atomic Energy Research Institute (KAERI) has recently conducted PASCAL experiment to confirm the performance of PAFS. From the work, it is founded that the condensation heat transfer coefficient predicted by best estimated safety analysis code MARS (Multi-dimensional Analysis of Reactor Safety) was underestimated compared to the experimental data. Shah correlation embedded in MARS code is the typical model using the empirical two-phase multiplier to determine condensation heat transfer coefficient for annular flow in the condensing tube. On the other hand, the PASCAL experiment indicated that a stratified-wavy flow generally tends to occur in the downward inclined tube of the condensation heat exchanger. Therefore, in order to improve the prediction capability of safety analysis codes for PAFS, the present study has proposed a new condensation heat transfer model package for the nearly horizontal tube, which determines mechanistically the local heat transfer coefficient based on the flow regimes. To enhance prediction capability of one-dimensional best estimated code MARS for the PAFS of the Korean 3.5 generation nuclear power plant APR+, a new condensation heat transfer model package has been developed. The model package consists of the one-dimensional separated model for the void fraction, a flow regime model based on wetted angle, and the condensation heat transfer correlations. The model package considers the inclination angle of the condensing tube and various flow regimes that are expected in the tube during condensation process.

  20. Numerical Study on the Effect of Reactor Internal Structure Geometry Treatment Method on the Prediction Accuracy for Scale-down APR+ Flow Distribution

    International Nuclear Information System (INIS)

    Internal structures, especially those located in the upstream of a reactor core, may have a significant influence on the core inlet flow rate distribution depending on both their shapes and the relative distance between the internal structures and the core inlet. In this study, to examine the effect of the reactor internal structure geometry treatment method on the prediction accuracy for the scale-down APR+ flow distribution, simulations with real geometry modeling were conducted using ANSYS CFX R.14, a commercial computational fluid dynamics software, and the predicted results were compared with those of the porous medium assumption. It was concluded that the core inlet flow distribution could be predicted more accurately by considering the real geometry of the internal structures located in the upstream of the core inlet. Therefore, if sufficient computational resources are available, an exact representation of these internal structures, for example, lower support structure bottom plate and ICI nozzle support plate, is needed for the accurate simulation of the reactor internal flow

  1. Observations of TeV gamma-rays from Mrk 421 during Dec. 2005 to Apr. 2006 with the TACTIC telescope

    CERN Document Server

    Yadav, K K; Tickoo, A K; Rannot, R C; Godambe, S; Koul, M K; Dhar, V K; Thoudam, S; Bhatt, N; Bhattacharya, S; Chanchalani, K; Goyal, H C; Kaul, R K; Kothari, M; Kotwal, S; Koul, R; Sahayanathan, S; Sharma, M; Venugopal, K

    2007-01-01

    The TACTIC $\\gamma$-ray telescope has observed Mrk 421 on 66 clear nights from Dec. 07, 2005 to Apr. 30, 2006, totalling $\\sim$ 202 hours of on-source observations. Here, we report the detection of flaring activity from the source at $\\geq$ 1 TeV energy and the time-averaged differential $\\gamma$-ray spectrum in the energy range 1-11 TeV for the data taken between Dec. 27, 2005 to Feb. 07, 2006 when the source was in a relatively higher state as compared to the rest of the observation period. Analysis of this data spell, comprising about $\\sim$97h reveals the presence of a $\\sim 12.0 \\sigma$ $\\gamma$-ray signal with daily flux of $>$ 1 Crab unit on several days. A pure power law spectrum with exponent $-3.11\\pm0.11$ as well as a power law spectrum with an exponential cutoff $(\\Gamma = -2.51\\pm0.26$ and $E_0=(4.7\\pm2.1) TeV)$ are found to provide reasonable fits to the inferred differential spectrum within statistical uncertainties. We believe that the TeV light curve presented here, for nearly 5 months of ext...

  2. Les westerns de John Ford : Du libéralisme d’avant-guerre au conservatisme d’après-guerre

    Directory of Open Access Journals (Sweden)

    Jean-Pierre Esquenazi

    2012-05-01

    Full Text Available L’article propose un moyen de mesurer l’influence sur les cinéastes du milieu dans lequel ils vivent. Sont examinés trois ensembles de westerns de John Ford (réalisés avant guerre, dans l’immédiat après guerre et dans la décennie 1955-1965. Chaque groupe est lié à une situation particulière de l’institution hollywoodienne et de la communauté des cinéastes. L’étude de la mise en scène de scènes récurrentes dans tous ces films révèle des différences pertinentes. Celles-ci peuvent être comprises comme des réactions à l’actualité sociale et politique de Hollywood. The article proposes a way to measure the influence on filmmakers of the environment in which they live. Three wholes of westerns, produced during the pre-war, during the immediate post war and during the decade 1955-1965, are reviewed. Each group is linked to a particular situation of the Hollywood industry. The study of the mise en scene of recurrent scenes in these films reveals relevant differences. These can be understood as reactions to the social and political state of the Hollywood industry.

  3. A study on Requirements of Data Base Translator for APR1400 Computerized Procedure System at Shin-Hanul unit 1 and 2

    International Nuclear Information System (INIS)

    The CPS is one of the Man Machine Interface (MMI) resources and the CPS can directly display plant graphic objects which are in the Digital Control System (DCS). And the CPS can send a request to DCS to provide DCS screen which is called step support display through DCS link button on a computerized procedure. The procedure writers can insert DCS graphic information to computerized procedure through data base which is provided by CPS Editing System (CPSES). The data base which is provided by CPSES conforms to the naming rule of DCS graphic objects. The naming rule of DCS graphic objects is defined by vendor thus status of DCS graphic objects which are in computerized procedure at Shin-Kori plant cannot be displayed on CPS at Shin-Hanul plant. To use computerized procedure which is written by other plant procedure writer, DCS graphic objects shall be translated by its plant data base. This paper introduces requirements of data base translator to reduce translation and re-inserting graphic objects burden. This paper introduces the requirements of data base translator of CPSES for APR1400 CPS at Shin-Hanul unit 1 and 2. The translator algorithms shall be tested to update data base of CPSES effectively. The prototype of translator is implemented and is being tested using real plant DB. This translator can be applied to Shin- Hanul unit1 and 2 through software V and V

  4. Anti-leukaemic effects induced by APR-246 are dependent on induction of oxidative stress and the NFE2L2/HMOX1 axis that can be targeted by PI3K and mTOR inhibitors in acute myeloid leukaemia cells.

    Science.gov (United States)

    Ali, Dina; Mohammad, Dara K; Mujahed, Huthayfa; Jonson-Videsäter, Kerstin; Nore, Beston; Paul, Christer; Lehmann, Sören

    2016-07-01

    The small molecule APR-246 (PRIMA-1(MET) ) is a novel drug that restores the activity of mutated and unfolded TP53 protein. However, the mechanisms of action and potential off-target effects are not fully understood. Gene expression profiling in TP53 mutant KMB3 acute myeloid leukaemia (AML) cells showed that genes which protected cells from oxidative stress to be the most up-regulated. APR-246 exposure also induced reactive oxygen species (ROS) formation and depleted glutathione in AML cells. The genes most up-regulated by APR-246, confirmed by quantitative real time polymerase chain reaction, were heme oxygenase-1 (HMOX1, also termed HO-1), SLC7A11 and RIT1. Up-regulation of HMOX1, a key regulator of cellular response to ROS, was independent of TP53 mutational status. NFE2L2 (also termed Nrf2), a master regulator of HMOX1 expression, showed transcriptional up-regulation and nuclear translocation by APR-246. Down-regulation of NFE2L2 by siRNA in AML cells significantly increased the antitumoural effects of APR-246. The PI3K inhibitor wortmannin and the mTOR inhibitor rapamycin inhibited APR-246-induced nuclear translocation of NFE2L2 and counteracted the protective cellular responses to APR-246, resulting in synergistic cell killing together with APR-246. In conclusion, ROS induction is important for antileukaemic activities of APR-246 and inhibiting the protective response of the Nrf-2/HMOX1 axis using PI3K inhibitors, enhances the antileukaemic effects. PMID:26991755

  5. L'aprenentatge de l'anglès a través de l'educació física : el programa 'Mou-te i aprèn'. English language acdquisition through Physical Education: the 'Mou-te i aprèn' programme.

    OpenAIRE

    Coral, Josep

    2010-01-01

    L’objecte d’estudi d’aquest article és la relació entre l’educació física i l’aprenentatge de la llengua anglesa, per mitjà de l’enfocament educatiu AICLE (CLIL, en anglès), concretat en el programa Mou-te i aprèn. Pel que fa a l’educació física es fonamenta en la metodologia d’instrucció directa: global pura, anàlisi progressiu i anàlisi seqüencial, complementada amb estratègies d’aprenentatge cooperatiu. L’educació física és una forma diferent i excel·lent d’aprendre la llengua. La combinac...

  6. L'analyse automatique des clichés associés aux détecteurs visuels en physique des particules. Traitement d'une expérience à haute statistique $\\overline{p}d A 4,72 GeV/c$ et exploitation des données des expériences EHS à haute résolution

    CERN Document Server

    Lutz, Jean-Robert

    L'analyse automatique des clichés associés aux détecteurs visuels en physique des particules. Traitement d'une expérience à haute statistique $\\overline{p}d A 4,72 GeV/c$ et exploitation des données des expériences EHS à haute résolution

  7. Traitement des données de sismique de puits acquises en 2007 sur le site de Soultz-sous-Forêts pour la caractérisation de la fracturation du réservoir géothermique

    OpenAIRE

    Lubrano Lavadera, Paul

    2013-01-01

    Les données de VSP multi-source/multi-offset acquises en 2007 sur le site géothermique de Soultz-sous-Forêts sont traitées et analysées. Des géophones placés dans les puits GPK3 et GPK4 entre 3 et 5 km de profondeur ont enregistré les ondes sismiques émises par deux vibrateurs placés en 24 positions de tir réparties dans un rayon de 5 km autour des puits. Après corrélation des enregistrements avec la source associée à chaque vibrateur, les différentes composantes du champ d'onde sont séparées...

  8. Connaissances, attitudes et pratiques de la population de l'aire de santé SAMBWA en rapport avec le traitement de l'onchocercose à l'ivermectine sous directives communautaires

    OpenAIRE

    Philippe, Cilundika Mulenga; Bienvenu, Yogolelo Asani; Francoise, Malonga Kaj; Eric, Mukomena Sompwe; Abdon, Mukalay wa Mukalay; Luboya, Oscar Numbi

    2014-01-01

    Introduction L'onchocercose constitue un problème majeur de santé publique et l'on a noté environ 13 millions de personnes affectées et 26 millions exposées au cours de l'année 2012 en RDC. L'objectif de notre étude est fournir les données sur le niveau de connaissance, d'attitudes et des pratiques de la communauté huit ans après le lancement de la distribution de l'ivermectine sous directives communautaires. Méthodes Il s'agit d'une étude descriptive transversale dans la communauté de l'aire...

  9. L'Arabie du Sud et la mer du IIIème siècle av. au VIème siècle apr. J.‑C.

    OpenAIRE

    Schiettecatte, Jérémie

    2012-01-01

    Etude de l'évolution du commerce maritime en Arabie du Sud du 3e siècle avant au 6e siècle après et de l'évolution des ports et du tracé des voies de navigation en fonction du contexte politique plus large (évolution de l'empire romain, de la Perse sassanide).

  10. Phylogenetic Diversity and Spatial Distribution of the Microbial Community Associated with the Caribbean Deep-water Sponge Polymastia cf. corticata by 16S rRNA, aprA, and amoA Gene Analysis

    OpenAIRE

    Meyer, Birte; Kuever, Jan

    2008-01-01

    Denaturing gradient gel electrophoresis (DGGE)-based analyses of 16S rRNA, aprA, and amoA genes demonstrated that a phylogenetically diverse and complex microbial community was associated with the Caribbean deep-water sponge Polymastia cf. corticata Ridley and Dendy, 1887. From the 38 archaeal and bacterial 16S rRNA phylotypes identified, 53% branched into the sponge-specific, monophyletic sequence clusters determined by previous studies (considering predominantly shallow-water sponge species...

  11. "Mēness aptiekas" farmaceitiskās aprūpes pakalpojumu kvalitātes izvērtējums un pilnveides iespējas

    OpenAIRE

    Matute, Anete

    2016-01-01

    Maģistra darbā „Mēness aptiekas” farmaceitiskās aprūpes pakalpojumu kvalitātes izvērtējums un pilnveides iespējas” autore, balstoties uz pakalpojumu kvalitātes novērtēšanas teorētiskajiem modeļiem, izvērtējusi „Mēness aptiekas” tīkla Jūrmalas aptieku sniegto pakalpojumu kvalitātes dažādas dimensijas. Mūsdienu apstākļos farmaceitiskā aprūpe ir kļuvusi par būtisku primārās veselības aprūpes sastāvdaļu, tādēļ šo pakalpojumu pieejamībai un kvalitātei tiek pievērsta aizvien lielāka uzmanība gan ...

  12. Análise do efeito não linear do patrimônio líquido no apreçamento de fundos de investimento em ações

    Directory of Open Access Journals (Sweden)

    Paulo Rogério Faustino Matos

    2012-01-01

    Full Text Available Este artigo faz uso do Capital Asset Pricing Model (CAPM, em sua versão canônica e com extensões não lineares, visando a apreçar um painel de 75 fundos de investimento em ações no Brasil, ao longo dos últimos 11 anos. O resultado sugere que a versão linear desse arcabouço não seja capaz de apreçar ou de prever retornos reais de fundos que possuam elevados patrimônio líquido (PL e outperformance, em relação ao índice da Bolsa de Valores de São Paulo (Ibovespa, corroborando evidências anteriores. A versão não linear com thresholds baseados no PL parece lidar melhor com a questão de alfas de Jensen significativos, apesar de ser estatisticamente indicada apenas para poucos fundos com elevado PL, mas baixa outperformance. Essa é uma evidência de que, apesar de o tamanho influenciar na gestão e, possivelmente, na performance de um fundo, a modelagem de apreçamento desse efeito deve ser feita linearmente.

  13. Coadministration of Hedera helix L. Extract Enabled Mice to Overcome Insufficient Protection against Influenza A/PR/8 Virus Infection under Suboptimal Treatment with Oseltamivir.

    Science.gov (United States)

    Hong, Eun-Hye; Song, Jae-Hyoung; Shim, Aeri; Lee, Bo-Ra; Kwon, Bo-Eun; Song, Hyuk-Hwan; Kim, Yeon-Jeong; Chang, Sun-Young; Jeong, Hyeon Gun; Kim, Jong Geal; Seo, Sang-Uk; Kim, HyunPyo; Kwon, YongSoo; Ko, Hyun-Jeong

    2015-01-01

    Several anti-influenza drugs that reduce disease manifestation exist, and although these drugs provide clinical benefits in infected patients, their efficacy is limited by the emergence of drug-resistant influenza viruses. In the current study, we assessed the therapeutic strategy of enhancing the antiviral efficacy of an existing neuraminidase inhibitor, oseltamivir, by coadministering with the leaf extract from Hedera helix L, commonly known as ivy. Ivy extract has anti-inflammatory, antibacterial, antifungal, and antihelminthic properties. In the present study, we investigated its potential antiviral properties against influenza A/PR/8 (PR8) virus in a mouse model with suboptimal oseltamivir that mimics a poor clinical response to antiviral drug treatment. Suboptimal oseltamivir resulted in insufficient protection against PR8 infection. Oral administration of ivy extract with suboptimal oseltamivir increased the antiviral activity of oseltamivir. Ivy extract and its compounds, particularly hedrasaponin F, significantly reduced the cytopathic effect in PR8-infected A549 cells in the presence of oseltamivir. Compared with oseltamivir treatment alone, coadministration of the fraction of ivy extract that contained the highest proportion of hedrasaponin F with oseltamivir decreased pulmonary inflammation in PR8-infected mice. Inflammatory cytokines and chemokines, including tumor necrosis factor-alpha and chemokine (C-C motif) ligand 2, were reduced by treatment with oseltamivir and the fraction of ivy extract. Analysis of inflammatory cell infiltration in the bronchial alveolar of PR8-infected mice revealed that CD11b+Ly6G+ and CD11b+Ly6Cint cells were recruited after virus infection; coadministration of the ivy extract fraction with oseltamivir reduced infiltration of these inflammatory cells. In a model of suboptimal oseltamivir treatment, coadministration of ivy extract fraction that includes hedrasaponin F increased protection against PR8 infection that could be

  14. Coadministration of Hedera helix L. Extract Enabled Mice to Overcome Insufficient Protection against Influenza A/PR/8 Virus Infection under Suboptimal Treatment with Oseltamivir.

    Directory of Open Access Journals (Sweden)

    Eun-Hye Hong

    Full Text Available Several anti-influenza drugs that reduce disease manifestation exist, and although these drugs provide clinical benefits in infected patients, their efficacy is limited by the emergence of drug-resistant influenza viruses. In the current study, we assessed the therapeutic strategy of enhancing the antiviral efficacy of an existing neuraminidase inhibitor, oseltamivir, by coadministering with the leaf extract from Hedera helix L, commonly known as ivy. Ivy extract has anti-inflammatory, antibacterial, antifungal, and antihelminthic properties. In the present study, we investigated its potential antiviral properties against influenza A/PR/8 (PR8 virus in a mouse model with suboptimal oseltamivir that mimics a poor clinical response to antiviral drug treatment. Suboptimal oseltamivir resulted in insufficient protection against PR8 infection. Oral administration of ivy extract with suboptimal oseltamivir increased the antiviral activity of oseltamivir. Ivy extract and its compounds, particularly hedrasaponin F, significantly reduced the cytopathic effect in PR8-infected A549 cells in the presence of oseltamivir. Compared with oseltamivir treatment alone, coadministration of the fraction of ivy extract that contained the highest proportion of hedrasaponin F with oseltamivir decreased pulmonary inflammation in PR8-infected mice. Inflammatory cytokines and chemokines, including tumor necrosis factor-alpha and chemokine (C-C motif ligand 2, were reduced by treatment with oseltamivir and the fraction of ivy extract. Analysis of inflammatory cell infiltration in the bronchial alveolar of PR8-infected mice revealed that CD11b+Ly6G+ and CD11b+Ly6Cint cells were recruited after virus infection; coadministration of the ivy extract fraction with oseltamivir reduced infiltration of these inflammatory cells. In a model of suboptimal oseltamivir treatment, coadministration of ivy extract fraction that includes hedrasaponin F increased protection against PR8

  15. Inhibitory effect of cinnamaldehyde, derived from Cinnamomi cortex, on the growth of influenza A/PR/8 virus in vitro and in vivo.

    Science.gov (United States)

    Hayashi, K; Imanishi, N; Kashiwayama, Y; Kawano, A; Terasawa, K; Shimada, Y; Ochiai, H

    2007-04-01

    We have investigated the inhibitory effect of trans-cinnamaldehyde (CA), one of the principal constituents of essential oil derived from Cinnamomi cortex, on the growth of influenza A/PR/8 virus in vitro and in vivo. When 1-h drug treatment was initiated at various times post-infection (p.i.) in Madin-Darby canine kidney cells using a fixed dose of CA (40 microM), the maximum inhibitory effect (29.7% virus yield of control) was obtained when drug treatment was started at 3h p.i. Under the same treatment schedule, CA inhibited the virus growth in a dose-dependent manner (20-200 microM), and, at 200 microM, the virus yield was reduced to an undetectable level. RT-PCR and SDS-PAGE analyses showed that CA inhibited viral protein synthesis at the post-transcriptional level. In mice infected with the lung-adapted PR-8 virus, inhalation (50mg/cage/day) and nasal inoculation (250 microg/mouse/day) of CA significantly increased survival rates on the 8 days to 100% and 70%, respectively, in contrast to a survival rate of 20% in the untreated control group. Importantly, inhalation of CA caused virus yield reduction by 1 log in bronchoalveolar lavage fluid on day 6 after infection, compared with that of the untreated control group. These findings might provide further support to the empirical indication of Cinnamomi cortex-containing Kampo medicines for acute respiratory infectious diseases. PMID:17303260

  16. Le devenir des enfants vivant avec le VIH/sida sous traitement antirétroviral hautement actif, Cas de l’Hôpital Heal Africa de Goma, du 1e Janvier 2010 au 31 Décembre 2011.

    Directory of Open Access Journals (Sweden)

    Richard Bitwe Mihanda

    2013-09-01

    Full Text Available RÉSUMÉ Objectifs : Analyser les paramètres socio-démographiques de ces enfants, ainsi que ceux de leurs parents ; Evaluer le gain pondéral chez ces enfants à 6 mois, 12 mois, 18 mois et 24 mois ; Déterminer le profil évolutif des lymphocytes T CD4+ durant la période de traitement ; Déterminer le rôle des ARV dans l’amélioration de la qualité de vie des enfants vivant avec le VIH/SIDA (taux de décès, survenue des Infections opportunistes ; Déterminer le taux de survie des enfants vivant avec le VIH sous ARV en une année et deux ans ; Evaluer les effets secondaires chez ces enfants aux ARV. Méthode : étude rétrospective portant sur le devenir de 998 cas d’enfants vivant avec le VIH/SIDA sous traitement antirétroviral hautement actif à l’Hôpital Heal Africa dans le service CAP suivi en 2 ans (du 1e janvier 2010 au 31 décembre 2011. L’étude comportait une exploitation des registres de la consultation, des dossiers des enfants hospitalisées et des livrets ou fiches des malades suivis en ambulatoires quand cela était possible. La mesure statistique utilisée était le calcul de pourcentage.Résultats: 79, 15% des mères sont séropositives; la majorité des ces enfants soit 61,1% ont un âge compris entre 3-10 ans et 43,48% d’entre eux sont orphelins de père et de mère. Le sexe ratio est 1, 85 en faveur des filles. Ces enfants ont été contaminés par voie sexuelle dans 51,30% des cas ; à l’admission, seulement 9,32% des enfants avaient un bon état nutritionnel et à la fin de l’étude ce taux est augmenté de 64,60%. Le gain pondéral est de 46%. 42,6% des ces enfants avaient un déficit immunitaire léger à l’admission ; 80,4% n’ont pas présenté les infections opportunistes; la plupart des ces enfants était sous AZT+3TC+NVP dans 79,6% des cas ; 89,1% des ces enfants avaient une bonne observance thérapeutique et 80,3% des enfants sous ARV hautement actif avaient une bonne évolution clinique. Le

  17. Croire après la bombe : les interactions entre violence, religion et développement au Sri Lanka

    Directory of Open Access Journals (Sweden)

    Indika Bulankulame

    2013-03-01

    Full Text Available Pendant les trente ans qu’a duré la guerre civile au Sri Lanka, de nombreux citoyens ont été touchés par des attentats à la bombe destinés à perturber la vie quotidienne, non seulement dans les zones de guerre mais aussi dans les quartiers urbains, particulièrement à Colombo, la capitale. Si beaucoup ont perdu la vie, d’autres ont survécu, mais restent profondément meurtris, handicapés et traumatisés. Le présent article explore la signification de la « survie » telle que l’ont éprouvée les personnes dotées du nouveau statut de « victimes d’attentats à la bombe ». Son auteur s’interroge sur la capacité des survivants à assumer leur rôle de soutien de famille et/ou à faire face aux graves bouleversements économiques consécutifs aux profonds changements survenus dans leur vie. L’article constate de manière générale qu’en raison de la perte de revenus et de l’incapacité de participer pleinement à l’économie de marché, les survivants sont relégués à la marge des grands débats sur le développement et des possibilités qui en découleraient. La fin des hostilités a marqué un tournant clair en faveur du développement du Sri Lanka et, dans cette période cruciale d’après-guerre, il importe de se pencher sur les différentes façons dont la religion peut répondre aux besoins des survivants. C’est pourquoi l’interaction dynamique entre religion, violence politique et développement est mise en relief. Dans l’examen des mécanismes d’adaptation et de survie, il est question des réponses qu’offre la religion à la mondialisation (néolibérale tributaire du marché et à l’exposition à la terreur et à la violence, en atténuant l’expérience des traumatismes et en permettant aux survivants de se confronter à la réalité au quotidien.

  18. Régénération du pin d'Alep en Basse Provence. Impact des traitements du sol, de la végétation et des rémanents.

    OpenAIRE

    Prévosto, B.; Ripert, C.; Favand, G.; Lopez, J. M.; R. Esteve; W. Martin; N'Diaye, A.

    2009-01-01

    / Ce travail vise à étudier l'impact de différents types de travaux de la végétation et du sol ainsi que le rôle des rémanents sur la régénération du pin d'Alep. Après une coupe de régénération dans une pinède âgée, les travaux suivants ont été testés : broyage mécanique de la végétation, broyage suivi d'un crochetage simple ou double, brûlage contrôlé et témoin. L'effet des rémanents a été testé selon deux modalités : les branches issues de la coupe d'éclaircie du peuplement ont été soit éli...

  19. Effects of cell differentiation on replication of A/WS/33, WSN, and A/PR/8/34 influenza viruses in mouse brain cell cultures: biological and immunological characterization of products.

    OpenAIRE

    Bradshaw, G L; Schlesinger, R W; Schwartz, C D

    1989-01-01

    The responses of mouse embryo brain (MEB) cell cultures and of Madin-Darby canine kidney cells and chicken embryo fibroblasts to infection with A/PR/8/34 (PR8), A/WS/33 (WS), or the neurovirulent WSN variant were compared in terms of (i) single-cycle yields of hemagglutinating and associated neuraminidase (NA) activities and plaque-forming particles, the latter with or without trypsin activation [PFU(TR++) or PFU(TR--), respectively], and (ii) expression of nucleoprotein (NP), M1, and NS1 pro...

  20. 冷战后法国外交政策的调整%La rénovation de la politique diplomatique en France aprés la Guerre froide

    Institute of Scientific and Technical Information of China (English)

    汪波

    2002-01-01

    Le gouvemement francais a rénové sa politique diplomatique après la guerre froide. Cette rénovation consiste à coopérer avec les Etats-Unis au sein de LOTAN, à participer d′avantage au proeessus de paix au Moyen-Orient et à exercer plus dinfluence sur lesaffaires africaines. Basée sur une reconnaissance du changement de la situation internationale, cette rénovation a pour objectif de consolider la position de la France au sein de la communauté internationale.

  1. L’exclusion des scientifiques allemands et de la langue allemande des congrès scientifiques internationaux après la Première Guerre mondiale

    OpenAIRE

    Reinbothe, Roswitha

    2013-01-01

    Après la Première Guerre mondiale les académies des sciences des pays alliés décidèrent de boycotter les scientifiques allemands et la langue allemande et fondèrent en même temps de nouvelles organisations scientifiques internationales : le Conseil international de recherches pour les sciences, qui chapeautait des unions internationales dans les disciplines les plus importantes, et l’Union académique internationale pour les sciences de l’homme. Les langues principales de ces organisations éta...

  2. Effet du numéro d'oestrus et du nombre de jours après le vêlage sur la probabilité de conception chez les vaches laitières

    DEFF Research Database (Denmark)

    Friggens, Nic; Labouriau, Rodrigo

    été observés quotidiennement pour toutes les vaches, du vêlage jusqu'à la gestation confirmée ou jusqu'à deux cent quatre-vingt dix jours après le vêlage. Des inséminations ont été effectuées à chaque chaleur observée à partir du trente-cinquième jour post partum jusqu'à ce que la vache ait été jugée...

  3. Les incendies de forêt : une actualité brûlante à traitement médiatique à « show ». Analyse des reportages sur les incendies de forêt dans les journaux télévisés de TF1 de 2002 à 2004

    OpenAIRE

    Boutefeu, Benoit

    2008-01-01

    Les incendies de forêt constituent une actualité récurrente, comme en témoignent les nombreux reportages diffusés chaque année dans les journaux télévisés estivaux. Pour décrypter le traitement médiatique réservé à cet évènement somme toute habituel et banal mais néanmoins spectaculaire et fascinant, nous avons eu recours à des méthodologies qualitatives et quantitatives. Des corpus de reportages traitant de cette thématique et diffusés dans les journaux télévisés de TF1 entre 2002 et 2004 on...

  4. Procédé de fixation de CO2 et de traitement de déchets organiques par couplage d'un système de digestion anaérobie et d'un système de production de microorganismes phytoplanctoniques

    OpenAIRE

    Bernard, Olivier; Bougaran, Gaël; Cadoret, Jean-Paul; Kaas, Raymond; Latrille, Eric; Sialve, Bruno; Steyer, Jean-Philippe

    2010-01-01

    L'invention concerne un procédé de fixation de CO2 et de traitement de déchets organiques, dans lequel on traite des microorganismes (105) issus d'une culture phytoplanctonique et des déchets organiques (104) dans un réacteur d'hydrolyse (101); on traite au moins une partie d'un effluent liquide (109) sortant du réacteur d'hydrolyse dans un réacteur de méthanisation (102); on traite une phase liquide (127) et du biogaz à épurer (110) sortant de l'étape (a") dans une unité de culture de microo...

  5. Optimisation énergétique des procédés de séparation en raffinage et en traitement de gaz naturel Optimal Use of Energy in Separation Processes for Refining and Natural Gas Treatment

    Directory of Open Access Journals (Sweden)

    Rojey A.

    2006-11-01

    Full Text Available Cet article présente une méthode d'optimisation des procédés de séparation basée sur une analyse thermodynamique. Cette analyse s'appuie sur un bilan exergétique qui est établi dans le cas général d'un système quelconque opérant en régime permanent. Les facteurs qui conditionnent le rendement exergétique d'un procédé de séparation sont ensuite examinés. Il en résulte une méthode d'optimisation basée sur une réduction des irréversibilités thermodynamiques. Des exemples concrets d'application en raffinage et en traitement de gaz naturel sont présentés, et on montre comment cette analyse peut déboucher sur la conception de procédés innovants. The optimization of separation units in refining and natural-gas processing must take into consideration new needs and constraints that may seem incompatible. New installations must be designed not only on the basis of energy optimization but also by seeking to minimize investments and to respect new rules concerning environmental protection. The optimization described in this article is based on a thermodynamic analysis of different material and energy exchanges, The energybalance provides a suitable basis for making this analysis. It leads to the defining of an exergy efficiency that is all the higher as the thermodynamic irreversibilities are reduced, and that tends toward one for an ideal reversible system. For a separation process, a separation exergyterm is defined that correspond to the minimum separation work . Distillation is the basic separation operation. The exergy efficiency of this operation is low, and we show that, even in a relatively favorable cas, it is no greater than a value of about 6%. For an atmospheric distillation operation of crude oil, the exergy efficiency is about 4%. This overall exergy efficiency is the product of an external exergy efficiency and an internal exergy efficiency. The external exergy efficiency can be improved by better thermal

  6. Il trattamento dei detenuti sex offenders nel carcere di Castelvetrano (TP/Le traitement des délinquants sexuels dans la prison de Castelvetrano (TP, Italie/The treatment of sex offenders in Castelvetrano (TP prison

    Directory of Open Access Journals (Sweden)

    Angela Adragna

    2016-04-01

    Full Text Available L’articolo è incentrato sull’analisi del programma trattamentale offerto ai detenuti sex offenders nella Casa Circondariale di Castelvetrano (Trapani, nel periodo 2009-2012, attraverso il progetto “www…parliamonepure”. L’analisi ha consentito in particolare di evidenziare come i detenuti sex offenders, nonostante la loro “ricercata invisibilità” nel contesto penitenziario, abbisognino di interventi specifici, intramurari ed extramurari, volti ad evitare una futura recidiva. In tal senso si auspica che le attività trattamentali di tipo psico-sociale di gruppo nel contesto restrittivo possano essere svolte con logica di continuità, anche se in spazi e tempi diversi, affinché il detenuto possa essere adeguatamente supportato sia all’interno del carcere che all’esterno, con presa in carico da parte degli Uffici di Esecuzione Penale Esterna (U.E.P.E. nelle prime fasi del reingresso in ambiente libero tramite interventi di assistenza post-penitenziaria e di invio eventuale alle strutture sanitarie di riferimento. L’article est consacré à l’analyse du programme de traitement offert aux délinquants sexuels dans la prison de Castelvetrano, de 2009 à 2012, dans le cadre du projet « Venez nous en parler » (“www…parliamonepure”.L’analyse a montré que les délinquants sexuels, malgré leur « requête d’invisibilité » dans la prison, ont besoin de mesures spécifiques, en milieu carcéral et à l’extérieur, pour prévenir la récidive. Dans ce contexte, il faut espérer que les mesures de resocialisation psychosociales puissent être réalisées avec continuité en prison et hors de prison. À l’extérieur de la prison, le condamné sera pris en charge par le service de probation (UEPE – Ufficio per l’Esecuzione Penale Esterna au cours des premières phases de sa réinsertion et des soins médicaux lui seront offert, si besoin est. The article focuses on the analysis of a treatment program provided to

  7. Quel contexte pour le traitement du discours?

    OpenAIRE

    Vion, Monique

    1995-01-01

    This article deals with context effects in discourse processing. It presents some of the theoretical problems that have arisen over the past twenty years from the ongoing interchange of ideas among the various branches of the cognitive sciences (linguistics, psycholinguistics, and artificial intelligence). Following a review of the different understandings of the term " context ", particularly in linguistics and psycholinguistics, the article discusses some of the fundamental issues raised wh...

  8. The gemstones processing; Le traitement des gemmes

    Energy Technology Data Exchange (ETDEWEB)

    Fritsch, E. [Laboratoire de physique cristalline, Institut des materiaux de Nantes (IMN), 44 - Nantes (France); Shigley, J. [Institut Americain de gemmologie (GIA), Carlsbad, Californie (United States); Lasnier, B. [Universite de Nantes, 44 - Nantes (France)

    1998-03-01

    Among the treatments that gemstones can be received, there is irradiation; by displacing electrons, the valence of ions can be changed and than the colour can be changed too. The example of diamonds, sapphires, or topazes are explained. (N.C.)

  9. Māsas rīcība pēcoperācijas brūču aprūpē ķirurģijas nodaļā

    OpenAIRE

    Spruntule, Inga

    2016-01-01

    Bakalaura darba tēma „Māsas rīcība pēcoperācijas brūču aprūpē ķirurģijas nodaļā” . Tēmas aktualitāti nosaka tas, ka ik dienu slimnīcās veic neskaitāmas operācijas un infekcija ir viena no komplikācijām pēcoperācijas periodā. Inficēšanās iemesli ir dažādi. Roku nemazgāšana ir viens no galvenajiem veidiem, kā izplatās infekcija slimnīcās. Ir aktuāli noskaidrot māsas rīcību pēcoperācijas brūču aprūpē, jo aseptikas un antiseptikas, roku mazgāšana un dezinfekcija, kā arī cimdu lietošana var mazi...

  10. Māsu izpratnes pilnveide par pacientu izglītošanu primārajā un sekundārajā veselības aprūpē

    OpenAIRE

    Fridrihsone, Baiba

    2016-01-01

    Pacientu izglītošana ir māsas pienākums, tomēr, māszinības programmās, kā arī veselības aprūpes iestādēs, pacientu izglītošana tiek veikta nepilnīgi vai netiek veikta nemaz. Problēmas risināšanai tika izvirzīts mērķis: izzināt kā pilnveidot māsu izpratni par pacientu izglītošanu primārajā un sekundārajā veselības aprūpē. Pētāmā grupa bija Latvijas Universitātes, Medicīnas fakultātes, profesionālās bakalaura studiju programmas (PBSP) “Māszinības” 4.kursa studenti, kuri pārstāvēja sešas māsu ap...

  11. L’aprenentatge de l’anglès a través de l’educació física: el programa ‘Mou-te i aprèn’ English language acquisition through physical education: the ‘Mou-te i aprèn’ programme El aprendizaje del inglés a través de la educación física: el programa ‘Mou-te i aprèn’

    Directory of Open Access Journals (Sweden)

    Josep Coral i Mateu

    2011-09-01

    Full Text Available L’objecte d’estudi d’aquest article és la relació entre l’educació física i l’aprenentatge de la llengua anglesa, per mitjà de l’enfocament educatiu AICLE (CLIL, en anglès, concretat en el programa Mou-te i aprèn. Pel que fa a l’educació física es fonamenta en la metodologia d’instrucció directa: global pura, anàlisi progressiu i anàlisi seqüencial, complementada amb estratègies d’aprenentatge cooperatiu. L’educació física és una forma diferent i excel·lent d’aprendre la llengua. La combinació de les diferents metodologies i tècniques són molt efectives per millorar alhora el llenguatge, la motricitat i la salut. ______________________________________________ L’objet d’étude de cet article est la relation entre ’éducation physique et l’apprentissage de la langue anglaise, grâce à la perspective éducative Content and Language Integrated Learning (CLIL, concrétisée dans le programme Mou-te i aprèn. En ce qui concerne l’éducation physique, elle est fondée sur la méthodologie d’instruction directe, globale, pure, d’analyse progressive et d’analyse séquentielle, complétée par des stratégies d’apprentissage coopératif. L’éducation physique est une manière différente et excellente d’apprendre la langue. La combinaison des différentes méthodologies et techniques est tout à fait effective pour améliorer la langue, la motricité de même que la santéThe aim of this article is to explore the relationship between physical education and learning the English language through the CLIL (Content and Language Integrated Learning approach, implemented through the Mou-te i aprèn [‘Move yourself and learn’] programme. With regard to physical education it is based on the methodology of direct instruction: pure global, progressive analysis and sequential analysis, supplemented with cooperative learning strategies. Physical education is a different, effective way to learn the

  12. L’aprenentatge de l’anglès a través de l’educació física: el programa ‘Mou-te i aprèn’ English language acquisition through physical education: the ‘Mou-te i aprèn’ programme El aprendizaje del inglés a través de la educación física: el programa ‘Mou-te i aprèn’

    OpenAIRE

    Josep Coral i Mateu

    2011-01-01

    L’objecte d’estudi d’aquest article és la relació entre l’educació física i l’aprenentatge de la llengua anglesa, per mitjà de l’enfocament educatiu AICLE (CLIL, en anglès), concretat en el programa Mou-te i aprèn. Pel que fa a l’educació física es fonamenta en la metodologia d’instrucció directa: global pura, anàlisi progressiu i anàlisi seqüencial, complementada amb estratègies d’aprenentatge cooperatiu. L’educació física és una forma diferent i excel·lent d’aprendre la llengua. La combinac...

  13. Analyse du traitement et de la gestion durable des boues d’épuration en Corse. Proposition de solutions énergétiques alternatives, axées sur la méthanisation des boues avec production d’énergies, aux méthodes appliquées en Corse. Utilisation de l’outil d’aide multicritère à la décisiondans le cadre du surclassement de ces nouveaux procédés.

    OpenAIRE

    TRAMONI, Félicien

    2015-01-01

    La qualité des boues est directement liée à la qualité des étapes de traitement présentes au sein d’une station d’épuration. En termes de traitement et d’élimination des boues, nous observons de la part des acteurs locaux, une volonté d’abandon définitif et durable de la filière « dépôt en centre de stockage », étant donnée une règlementation et des plans régionaux (notamment le PREDIS de Corse), toujours plus exigeant en termes de valorisations des déchets industriels et spéciaux. Nous obser...

  14. L’abdication du Congrès après le 11 septembre : crise constitutionnelle ou politique ?

    Directory of Open Access Journals (Sweden)

    Maya KANDEL

    2011-09-01

    Full Text Available L’effondrement des tours jumelles de Manhattan le 11 septembre 2001 a renversé le rapport existant entre législatif et exécutif américains. Alors que certains avaient pu qualifier George W. Bush après son élection de « premier président post-impérial » face à un Congrès en pleine reconquête de ses prérogatives depuis la fin de la guerre froide, l’entrée des Etats-Unis dans la « guerre contre la terreur » a vu le retour d’une présidence impériale, et réduit les parlementaires à un rôle de quasi figuration. Historiquement, l’évolution semble attendue. Les phases d’extraversion de l’Amérique ont toujours correspondu à une affirmation de la prééminence présidentielle. Plus encore, en temps de crise et dès lors que la sécurité du peuple est en jeu, la prérogative constitutionnelle qui fait du président le commandant en chef des forces armées du pays lui donne une marge de manœuvre incomparable dans l’élaboration de la politique étrangère. Il était logique que le 11 septembre garantisse à Bush la victoire sur le Congrès dans la « compétition pour le privilège de conduire la politique étrangère du pays ». Les parlementaires se sont montrés particulièrement complaisants face à l’expansion des pouvoirs de l’exécutif, qu’ils ont souvent eux-mêmes autorisée – en particulier dans les mois qui ont suivi les attaques, puis par la suite, en raison de l’utilisation habile par Bush et le parti républicain d’une « politique de la peur » particulièrement efficace. Mais l’Administration Bush est allée beaucoup plus loin que cette simple logique. Par la pratique des signing statements, « déclarations de signature » ajoutées aux lois, le Président s’est accordé le droit d’interpréter, voire de choisir ou de corriger, certaines portions de la législation votée par le Congrès. Cette pratique n’a pas été inventée par Bush mais, qualitativement comme

  15. Confluences Méditerranée, n° 81, 2012/2, 236 p.Dossier : Algérie, 50 ans après

    OpenAIRE

    Mohammedi, Sidi Mohammed

    2015-01-01

    « L’Algérie fête cette année les 50 ans de son indépendance, une occasion pour revenir sur son parcours à la fois politique, économique et culturel. C’est l’objectif recherché par la revue Confluences Méditerranée à travers ce numéro consacré à « L’Algérie, 50 ans après » (p. 09). C’est ainsi qu’a ouvert Sid-Ahmed Souiah sa présentation en attirant l’attention que l’exhaustivité n’était pas recherchée pour choisir les thématiques retenues mais, plutôt, de présenter une variété de contribution...

  16. Aprèn història en anglès! Un projecte d’innovació de llengües estrangeres a l’Institut Julio Antonio de Móra d’Ebre

    OpenAIRE

    Loreto Meix-Boira

    2012-01-01

    Aprèn història en anglès! és un projecte d’innovació de llengües estrangeres creat per ensenyar història en anglès a estudiants de secundària la llengua materna dels quals no és l’anglès (CLIL, Content and Language Integrated Learning, també conegut com a AICLE, aprenentatge integrat de continguts i llengua estrangera ). El projecte consta de tres blocs que tracten aspectes polítics, socials, econòmics i culturals sobre el món antic, Egipte i Roma, i l’edat mitjana (Life in Ancient Egypt, Anc...

  17. La prévention du suicide chez l'adolescent hospitalisé après une tentative échouée: quel est le rôle infirmier ?

    OpenAIRE

    Chabanel, Fanny; Bagnoud, Perle; Roche-Meredith, Loriane; Dupuis, Patricia

    2012-01-01

    Plusieurs études menées dans des pays différents mettent en avant que le suicide des adolescents est un problème de santé publique de grande envergure. En effet, après plusieurs lectures d’articles de recherche, nous avons remarqué que dans la majorité des pays industrialisés le suicide des adolescents est une des trois premières causes de mortalité. Nous nous sommes donc questionnées à ce sujet et nous avons eu envie de connaître le rôle de l’infirmière quant à la prévention du suicide chez ...

  18. Apreçamento de opções sobre taxa de câmbio R$/US$ negociadas no Brasil: uma comparação entre os modelos Black e redes neurais artificiais

    Directory of Open Access Journals (Sweden)

    Leandro dos Santos Maciel

    2012-03-01

    Full Text Available No estudo aqui apresentado, aplicou-se um modelo de rede neural multicamadas para o apreçamento de calls sobre taxa de câmbio R$/US$, negociadas na Bolsa de Valores, Mercadorias & Futuros de São Paulo (BM&FBovespa, para o período de janeiro de 2004 a dezembro de 2007. A partir dos preços efetivamente praticados no mercado, comparou-se o desempenho entre essa técnica e o modelo de Black, utilizando-se métricas usuais de erro e testes estatísticos. Os resultados obtidos revelaram, em geral, a melhor adequação do modelo de inteligência artificial, em comparação ao modelo de Black, nos diferentes graus de moneyness.

  19. Professionnalisation à travers la socialisation internationale et les "usages de l'Europe". Le cas des organisations syndicales en Bulgarie, KNSB et KT Podkrepa, après 1989.

    OpenAIRE

    Spasova, Slavina

    2015-01-01

    Comment appréhender l’acteur syndical dans le changement des cycles historiques et « le passage, à la fin des années 80, d’une conjoncture économique à une autre, d’une forme syndicale à une autre ». (Mouriaux, René dans Launey, Michel 1990). En se passionnant par ce questionnement notre thèse de doctorat se penche sur l’étude de cas de la construction de l’acteur syndical et son rôle dans l’espace politique, économique et social en Bulgarie après 1989. Un pays qui à l’orée de l’instauration ...

  20. Caractéristiques spatiales de la couverture des buissons après différentes perturbations par le feu dans les Pyrénées

    OpenAIRE

    Montané, Francesc; Casals, Pere; Taull, Marc; Lambert, Bernard; Dale, Mark R.T.

    2009-01-01

    * Les empiètements boisés sur les prairies sont un phénomène mondial. Dans les Pyrénées, le feu a été utilisé comme un outil de gestion pour transformer une partie des empiètements boisés en prairies. * Cette étude vise à comparer les caractéristiques spatiales des couverts de buissons 4 ans après 4 différentes perturbations (feu prescrit, feu prescrit répété, feu spontané dans des buissons âgés de 20 ans et feu spontané dans buissons âgés de 5 ans), et aussi de comparer la couverture des bui...

  1. Magaly Del Vecchio-Drion, La Prise de Cordres et de Sebille, chanson de geste du xiiie siècle, édition d’après le ms. BN

    OpenAIRE

    Vecchio-Drion, Magaly Del

    2012-01-01

    La Prise de Cordres et de Sebille appartient au Cycle de Guillaume d’Orange, plus précisément, au Cycle des Narbonnais. Cet ensemble de chansons, qui se situe au moment des enfances de Guillaume, narre les exploits des frères du comte d’Orange après ce que l’on a coutume d’appeler le « département des fils Aymeri » et comprend les textes suivants : Aymeri de Narbonne, Narbonnais, Siège de Barbastre, Mort Aymeri de Narbonne. À ce noyau s’ajoutent Guibert d’Andrenas et La Prise de Cordres et de...

  2. Valutazione dell'appropriatezza dei ricoveri in un Policlinico Universitario: analisi mediante l'uso comparativo dei sistemi di classificazione isogravitá APR-DRG e Disease Staging e del PRUO

    Directory of Open Access Journals (Sweden)

    M. Volpe

    2003-05-01

    Full Text Available

    Obiettivi: valutare l’appropriatezza organizzativa dei ricoveri effettuati in un Policlinico Universitario attraverso la comparazione di due metodi, dei quali uno basato sui dati della scheda di dimissione ospedaliera ed utilizza, rispettivamente, i sistemi di classificazione iso-gravità APR-DRG e Disease Staging e l’altro sulla revisione delle cartelle cliniche mediante il PRUO.

    Metodi: oggetto di analisi sono i ricoveri ordinari effettuati nell’anno 2001 ed afferenti ai DRG inclusi nella delibera della Giunta Regionale del Lazio 864/2002 che recepisce il D.P.C.M. 29/11/2001 sui livelli essenziali di assistenza.

    Risultati: i risultati evidenziano che le due varianti del
    metodo basato sulla SDO (metodo APPRO mostrano quote di ricoveri inappropriati sovrapponibili rispetto al complesso dei ricoveri oggetto di analisi, ma con differenze anche rilevanti tra APR-DRG e Disease Staging in relazione ai singoli DRG considerati, riconducibili ai diversi algoritmi di attribuzione del livello di severità utilizzati dai due sistemi. L’analisi campionaria effettuata con il metodo PRUO su casi afferenti ai DRG della DGR 864/2002 caratterizzati da livelli di severità minimi evidenzia una proporzione di ricoveri inappropriati superiore a quella determinata tramite i metodi basati sulla SDO. Tale differenza è verosimilmente dovuta al ruolo del valore delle soglie percentuali di accettabilità individuate dalla Regione Lazio per ciascun DRG: le quote di ricoveri che eccedono tali soglie sono considerate inappropriate.

    Conclusioni: sulla base dei risultati ottenuti gli autori
    descrivono gli interventi organizzativi adottati per ottimizzare il contesto di erogazione delle prestazioni
    oggetto di analisi, discutono vantaggi e limiti dei metodi SDO-based e del metodo analitico PRUObased e ne propongono l

  3. Tarifa e Ocupação em Hotéis: provocando o modelo de apreçamento convencional

    Directory of Open Access Journals (Sweden)

    Eder Paschoal Pinto

    2010-07-01

    -style:italic; mso-bidi-font-style:normal;} p.Captulo, li.Captulo, div.Captulo {mso-style-name:Capítulo; mso-style-unhide:no; margin-top:12.0pt; margin-right:0cm; margin-bottom:12.0pt; margin-left:0cm; text-align:justify; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Times New Roman","serif"; mso-fareast-font-family:"Times New Roman"; font-weight:bold; mso-bidi-font-weight:normal;} .MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; font-size:10.0pt; mso-ansi-font-size:10.0pt; mso-bidi-font-size:10.0pt;} @page WordSection1 {size:612.0pt 792.0pt; margin:70.85pt 3.0cm 70.85pt 3.0cm; mso-header-margin:36.0pt; mso-footer-margin:36.0pt; mso-paper-source:0;} div.WordSection1 {page:WordSection1;} -->

    Resumo

    O objetivo central deste trabalho é discutir a relação entre tarifa e taxa de ocupação em hotéis. As teorias de segmentação de clientes, composto mercadológico e estratégia de apreçamento foram aplicadas ao estudo. Os hotéis de Santos classificados como Turístico e Luxo foram escolhidos intencionalmente. Oitenta e três por cento deles responderam ao

  4. Traitement stylistique et traitement idiolectal des singularités langagières

    OpenAIRE

    Philippe, Gilles

    2013-01-01

    Les notions de style et d’idiolecte semblent pouvoir être définies de la même façon : l’un et l’autre seraient constitués par la récurrence de traits langagiers particuliers permettant la construction d’une identité langagière. La stylistique aurait donc vocation à être, entre autres choses, une sorte de science des idiolectes littéraires. Si elle s’y refuse, c’est parce qu’alors le fait stylistique n’aurait plus aucun rendement interprétatif local. Une solution semble avoir été trouvée dans ...

  5. Anti-conservateur, anti-radical, pro-militant : Richard Rorty, ou la séparation de la philosophie et de l’Etat

    Directory of Open Access Journals (Sweden)

    David Barral

    2008-05-01

    Full Text Available Liste des abréviations pour les ouvrages de Richard Rorty :PSH : Philosophy and Social Hope (1999AOC : Achieving Our Country (1999ORT : Objectivity, Relativism, and Truth (1991Parmi les accueils les moins favorables réservés en France au pragmatisme du philosophe américain Richard Rorty, il en est un qui souligne parfaitement le problème qui va nous occuper ici, celui de la relation (ou de la non-relation entre philosophie et politique. Dans Recommencer la Philosophie : La philosophie amé...

  6. M.Buyle, Le mythe du retour à l’origine. Le conservateur face à l’authenticité et l’interprétation

    Directory of Open Access Journals (Sweden)

    2009-04-01

    Full Text Available Bel ouvrage que vient de publier l’Association professionnelle des Restaurateurs d’Oeuvres d’Art, APROA-BRK (ce second acronyme pour l’intitulé en langue flamande, soit Beroepsvereniging voor conservators-restaurateurs van kunstvoorwerpen: il s’agit en fait des postprints des quatrièmes journées d’étude qui se sont tenues à Bruxelles,  les 22 et 23 novembre 2007.Celles-ci ont rassemblé un public nombreux et attentif, à l’écoute des orateurs venus de France (Segolène Bergeon, Matei Lazarescu,...

  7. Aprèn història en anglès! Un projecte d’innovació de llengües estrangeres a l’Institut Julio Antonio de Móra d’Ebre

    Directory of Open Access Journals (Sweden)

    Loreto Meix-Boira

    2012-07-01

    Full Text Available Aprèn història en anglès! és un projecte d’innovació de llengües estrangeres creat per ensenyar història en anglès a estudiants de secundària la llengua materna dels quals no és l’anglès (CLIL, Content and Language Integrated Learning, també conegut com a AICLE, aprenentatge integrat de continguts i llengua estrangera . El projecte consta de tres blocs que tracten aspectes polítics, socials, econòmics i culturals sobre el món antic, Egipte i Roma, i l’edat mitjana (Life in Ancient Egypt, Ancient Rome i Middle Ages. Amb els materials creats per a aquest projecte, els estudiants tindran l’oportunitat de treballar amb textos atractius i amb una gran varietat d’activitats durant unes 140 hores. L’alumnat prendrà contacte amb les TIC (tecnologies de la informació i la comunicació, ja que part del material es troba a la xarxa i, a més, es tracta d’un projecte interdisciplinari, en el qual es treballen les ciències socials, l’anglès i les TIC. El material és adequat per utilitzar-lo amb alumnes de 12 a 15 anys.

  8. La chronologie du royaume de Qatabân du Ier siècle avant J.-C. au Ier siècle après J.-C.

    Directory of Open Access Journals (Sweden)

    Mounir Arbach

    2002-04-01

    Full Text Available Les nouvelles découvertes archéologiques et épigraphiques de ces dernières années, effectuées au cours des fouilles franco-italiennes à Tamna`, l'ancienne capitale du royaume de Qatabân, permettent d'établir une nouvelle chronologie des souverains de Qatabân entre le Ier siècle avant J.-C. et le Ier siècle après J.- C.The chronology of the kingdom of Qatabân, from the 1st century BC to the 1st century AD. Archaeological and epigraphical discoveries made in recent years by the Franco-Italian excavations at Tamna`, the ancient capital of the kingdom of Qatabân, allows us to establish a new chronology for the kings of Qatabân during the 1st century BC and the 1st century AD.

  9. Instruments used to measure or check {alpha}, {beta}, {gamma} activity and neutron emission in the course of processing ore or irradiated fuel; Appareils de mesure ou de controle {alpha}, {beta}, {gamma}, n, des circuits des usines de traitement du minerai ou du combustible irradie

    Energy Technology Data Exchange (ETDEWEB)

    Blanc, A.; Brunet, M.; Kermagoret, M.; Labeyrie, J.; Roux, G.; Vasseur, J.; Weil, J. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1959-07-01

    One of the methods checking ores in the course of treatment is the rapid quantitative determination of thorium. This measurement is carried out by means of a scintillation instrument which shows the {beta} and {alpha} coincidences of ThC and ThC'. The treatment of irradiated fuel is accompanied by a large number of radioactive checks relative to the performance of the fixation and elution operations of uranium in the ion exchangers, to the concentration of radioactivity of effluent sent from the plant into watercourses. The operations of fixation and elution of the uranium are checked automatically by an instrument which takes a sample of 5 cm{sup 3} of solution, evaporates it and measures its activity every 10 or 20 minutes. Plutonium concentrations are measured: - in the presence of strong {beta} {gamma} activities, by means of rotating cylinder detectors; - in the presence of weak {beta} {gamma} activities, by means of {alpha} detectors scanning a constant level liquid surface; - by means of fission chambers relatively insensitive to {gamma}. Fission product concentrations are measured by chambers, counters or scintillators, according to the amount of {gamma} activity present. Finally, the activity of effluent to be emptied into watercourses is checked by means of a scintillation instrument, which measures the {alpha} activity on the one hand, and on the other hand the {beta} {gamma} activity of residue from a 100 cm{sup 3} sample taken and evaporated in 20 minutes. (author) [French] Parmi les controles relatifs au minerai en cours de traitement, figure le dosage rapide de thorium. Cette mesure est realisee au moyen d'un appareillage a scintillation qui met en evidence la coincidence des emissions {beta} et {alpha} du ThC et du ThC'. Le traitement des combustibles irradies s'accompagne d'un grand nombre de controles radioactifs portant sur le fonctionnement des operations de fixation et d'elution de l'uranium dans les

  10. Les travaux de défense des châteaux delphinaux pendant la guerre de Cent Ans. Etude des réparations d'après les comptes de châtellenies au XIVe siècle

    OpenAIRE

    Nicolas, Nathalie

    2000-01-01

    International audience Cet article propose d'éclairer l'étude monumentale des châteaux delphinaux situés aujourd'hui dans le département des Hautes-Alpes d'après les réparations enregistrées par les châtelains du Dauphiné, dans leur comptabilité annuelle, en particulier au cours des années 1360 à 1400.

  11. La voie foncière et administrative en appui à la voie écologique et agricole pour une gestion décentralisée des ressources naturelles dans le programme Après-Barrages au Sénégal

    Directory of Open Access Journals (Sweden)

    Vincke, PP.

    1994-01-01

    Full Text Available Natural Resources Management, From The Ecological To The Land Tenure And Administrative Process : The "Apres-Barrages" Experience In Senegal. To get over the difficulty of convincing rural population to apply scientifical and technical recommandations related to nature conservation, an institutional process has been initiated in order to create a framework prompting local popular support and that could result in integrated rural space development supported by natural ressources management.

  12. Tēvu bērnības pieredze, depresijas un trauksmes simptomi perinatālajā periodā un to saistība ar viņu iesaistīšanos jaundzimušā aprūpē

    OpenAIRE

    Vedeņejeva, Veronika

    2016-01-01

    Maģistra darba pētījuma mērķis ir longitudināli izpētīt, kāda saistība pastāv starp vīrieša bērnības pieredzi un viņa iesaisti jaundzimušā bērna aprūpē, kā arī, vai topošo tēvu psiholoģiskais stāvoklis bērna perinatālajā periodā paredz viņa iesaistīšanos jaundzimušā aprūpē. Pie tam bija nozīmīgi izprast vīrieša psiholoģiskā stāvokļa dinamiku perinatālajā periodā, un vai izmaiņas psiholoģiskajā stāvoklī ir nozīmīgs faktors vīrieša iesaistei sava bērna aprūpē. Maģistra darba pētījums sastāvēja ...

  13. Emocionālās izdegšanas sindroms garīgās veselības aprūpē strādājošo māsu vidū

    OpenAIRE

    Cvetkovs, Andrejs

    2016-01-01

    Maģistra darba tēma – “Emocionālās izdegšanas sindroms garīgās veselības aprūpē strādājošo māsu vidū”. Pētījuma mērķis ir noskaidrot sakarības starp emocionālā intelekta līmeni un emocionālā izdegšanas sindroma attīstības pakāpi garīgās veselības aprūpē strādājošajām māsām. Saskaņā ar pētījuma tēmu tika izvirzīta hipotēze – pastāv sakarība starp garīgās veselības aprūpē strādājošo māsu emocionālā intelekta līmeni un emocionālās izdegšanas sindroma attīstības pakāpi. Lai sasniegtu pētījuma mē...

  14. Contribution to the study of physico-chemical properties of surfaces modified by laser treatment. Application to the enhancement of localized corrosion resistance of stainless steels; Contribution a l'etude des proprietes physico-chimiques des surfaces modifiees par traitement laser. Application a l'amelioration de la resistance a la corrosion localisee des aciers inoxydables

    Energy Technology Data Exchange (ETDEWEB)

    Pacquentin, W.

    2011-11-25

    integrite sur des periodes de plus en plus longues. L'objectif de ce travail de these est d'evaluer le potentiel d'un traitement de refusion laser pour ameliorer la resistance a la corrosion d'un acier inoxydable de type 304L; l'utilisation du laser dans le domaine des traitements de surface constituant un procede en pleine evolution a cause des changements recents dans la technologie des lasers. Dans le cadre de ce travail, le choix du laser s'est porte sur un laser nano-impulsionnel a fibre dopee ytterbium dont les caracteristiques permettent la fusion quasiinstantanee sur quelques microns de la surface traitee, immediatement suivie d'une solidification ultra-rapide avec des vitesses de refroidissement pouvant atteindre 1011 K/s. La combinaison de ces processus favorise l'elimination des defauts surfaciques, la formation de phases hors equilibre, la segregation d'elements chimiques et la formation d'une nouvelle couche d'oxyde dont les proprietes sont gouvernees par les parametres laser. Afin de les correler avec la reactivite electrochimique de la surface, l'influence de deux parametres laser sur les proprietes physicochimiques de la surface a ete etudiee: la puissance du laser et le taux de recouvrement des impacts laser. Pour clarifier ces relations, la resistance a la corrosion par piquration des surfaces traitees a ete determinee par des tests electrochimiques. Pour des parametres laser specifiques, le potentiel de piquration d'un acier inoxydable de type 304L augmente de plus de 500 mV traduisant ainsi une meilleure tenue a la corrosion localisee en milieu chlorure. L'interdependance des differents phenomenes resultant du traitement laser a rendu complexe la hierarchisation de leur effet sur la sensibilite de l'alliage teste. Cependant, il a ete montre que la nature de l'oxyde thermique forme au cours de la refusion laser et ses defauts sont du premier ordre pour l'amorcage des

  15. Correlation of serum vascular endothelial growth factor levels with plasma,serum and P-APR in breast cancer%乳腺癌患者血管内皮生长因子水平与外周血各成分的相关性

    Institute of Scientific and Technical Information of China (English)

    罗琼; 陶霖玉

    2009-01-01

    Objective To look for a better way to assay vascular endothelial growth factor(VEGF) and explore the correlation of serum VEGF levels with platelet and leucocyte count in breast cancer by comparison of peripheral blood plasma, serum and P-APR. Methods Blood samples were obtained from 42 patients with breast cancer and 20 healthy volunteers. Serum, plasma and P-APR samples were analyzed for VEGF using a commercially available sandwich ELISA, and assayed for semiquantitative measurement using microplatereader. At the same time, samples were analyzed by hematology analyzer. Results The level of VEGF in peripheral blood positively correlated to platelet (health control group: r=0.424, P=0.063) and leucocyte (health control group: r=0.443, P=0.050). The difference in VEGF values of P-APR between the localized breast cancer group and the health control group was statistically significant. Conclusion The level of VEGF in peripheral blood positively correlates to platelet and leucocyte. Platelet and leucocyte possibly secrete VEGF in vitro. Compared with serum and plasma, P-APR is the best section assaying VEGF in peripheral blood.%目的 寻求血管内皮生长因子(VEGF)的最佳检测方法并探讨VEGF水平与血小板、白细胞数量之间的关系.方法 采集42例乳腺癌患者(乳腺癌组)及20例健康志愿者(对照组)外周静脉血,用VEGF单克隆抗体ELISA法分别测定血清、血浆、P-APR VEGF水平,经酶标仪半定量,同时血细胞分析仪计数血小板、白细胞数量.结果 血清VEGF水平与血小板数量呈正相关(r=0.424,P=0.063),血清VEGF水平与白细胞数量呈正相关(r=0.443,P=0.050).P-APR中的VEGF含量在局限性乳腺癌组与对照组间的差异有统计学意义(P=0.007).结论 外周血VEGF水平与血小板、白细胞呈线性相关,血小板、白细胞在外周血中可分泌VEGF;相对血清、血浆,P-APR是外周血中VEGF检测的最佳成分.

  16. Monthly results of measurements: Apr 1997

    International Nuclear Information System (INIS)

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables

  17. Le CFEY et après…

    Directory of Open Access Journals (Sweden)

    François Burgat

    2000-09-01

    Full Text Available La livraison des Chroniques Yéménites 2000 s'inscrit dans le droit fil de l'initiative heureuse prise en 1993 par Frank Mermier, tout en prolongeant un effort entrepris dans la livraison précédente : allégées des comptes rendus de recherche cantonnés désormais au rapport scientifique du Centre et à son site Internet, les Chroniques entendent plus que jamais présenter un vaste panorama de la recherche sur le Yémen ou de la production intellectuelle de ce pays. La revue est désormais dotée d'un...

  18. PACITA: volta no. 06 (Apr. 2014)

    OpenAIRE

    PACITA Consortium (Hrsg.)

    2015-01-01

    volta – Science, Technology and Society in Europe; No. 06 – April 2014PACITA (Parliaments and civil society in Technology Assessment) has been a four-year EU financed project under FP7 aimed at increasing the capacity and enhancing the institutional foundation for knowledge-based policy-making on issues involving science, technology and innovation, mainly based upon the diversity of practices in Parliamentary Technology Assessment (PTA). The key practices in focus have been interactive in the...

  19. PACITA: volta no. 08 (Apr. 2015)

    OpenAIRE

    PACITA Consortium (Hrsg.)

    2015-01-01

    volta – Science, Technology and Society in Europe; No. 08 – April 2015PACITA (Parliaments and civil society in Technology Assessment) has been a four-year EU financed project under FP7 aimed at increasing the capacity and enhancing the institutional foundation for knowledge-based policy-making on issues involving science, technology and innovation, mainly based upon the diversity of practices in Parliamentary Technology Assessment (PTA). The key practices in focus have been interactive in the...

  20. PACITA: volta no. 04 (Apr. 2013)

    OpenAIRE

    PACITA Consortium (Hrsg.)

    2015-01-01

    volta – Science, Technology and Society in Europe; No. 04 – April 2013PACITA (Parliaments and civil society in Technology Assessment) has been a four-year EU financed project under FP7 aimed at increasing the capacity and enhancing the institutional foundation for knowledge-based policy-making on issues involving science, technology and innovation, mainly based upon the diversity of practices in Parliamentary Technology Assessment (PTA). The key practices in focus have been interactive in the...

  1. Võistlused : [kalasport, 28. apr. - 30. juun. 2012

    Index Scriptorium Estoniae

    2012-01-01

    Kevadkalake, Töörahva Kala, Kevadsärg, Vagula Röövik, Saadjärve Haug, EMV Õngitsemises (mehed), Linnakala, Suure-Jaani Spinning, Tuulekala Trolling, Rakvere Koger, Gorodenko Spinning, EMV Õngitsemises (naised ja noored)

  2. Monthly results of measurements: Apr 2001

    International Nuclear Information System (INIS)

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables

  3. Hard cheese structure after a high hydrostatic pressure treatment at 50 MPa for 72 h applied to cheese after brining

    OpenAIRE

    Saldo, Jordi; Sendra, Esther; Guamis, Buenaventura

    2001-01-01

    Structure d'un fromage à pâte dure après traitement par haute pression hydrostatique de 50 MPa durant 72 h appliquée après salage. L'application de la haute pression hydrostatique (50 MPa durant 72 h) sur les fromages, provoque des changements de la protéolyse primaire durant ce traitement. À partir de l'analyse des protéines solubilisées par des agents de rupture de liaisons, il a été conclu que l'incidence des liaisons hydrophobes et des ponts hydrogènes du fromage traité a été réduite aprè...

  4. Bitumen coating of the radio-active sludges from the effluent treatment plant at the Marcoule centre. Review of the progress reports 1, 2, 3 and 4 (1963); Enrobage par le bitume des boues radioactives de la station de traitement des effluents du centre de Marcoule. Mise au point des etats d'avancement 1, 2, 3 et 4. (1963)

    Energy Technology Data Exchange (ETDEWEB)

    Rodier, J.; Lefillatre, G.; Scheidhauer, J. [Commissariat a l' Energie Atomique, Centre de Production de Plutonium, Marcoule (France). Centre d' Etudes Nucleaires

    1963-07-01

    Besides the very high activity liquids containing fission products, the chemical treatment of irradiated fuels produces a large volume of aqueous effluents and solid waste of relatively low radioactivity. These weakly active products can be eliminated in the ground, in a hydrographic land system or in the sea. Techniques of evaporation, of resin concentration, and of coprecipitation give rise to inorganic sludges with a high water content. All these residues occupy a large volume and represent a far from negligible weight. In the case of the sludge, their relative fluidity necessitates a conditioning guaranteeing safe storage. The solution to the problem will consist in passing directly from a liquid or a suspension, to a solid whose structure is homogeneous and whose matter is inert with respect to the storage medium (soil, sea, etc. ). We have proposed to coat the radioactive products with bitumen. This article is designed to give a review of the studies undertaken on this method. It consists of a progress report rather than a final assessment. (authors) [French] En dehors des liquides de tres haute activite contenant des produits de fission, le traitement chimique des combustibles irradies produit un volume important d'effluents aqueux et de residus solides de radioactivite relativement faible. Ces produits, faiblement actifs, peuvent etre elimines dans le sol, dans un systeme hydrographique terrestre ou dans la mer. Les techniques d'evaporation, de concentration sur resine, de coprecipitation, permettent la decontamination prealable des liquides. La coprecipitation donne naissance a des boues minerales dont la teneur en eau est elevee. Tous ces residus occupent un volume important et representent un poids non negligeable. Dans le cas des boues, leur fluidite relative exige un conditionnement donnant toutes garanties de securite au stockage. La solution du probleme consistera a passer directement d'un liquide ou d'une suspension a un solide

  5. Rupture bilatérale des tendons rotuliens chez un sujet jeune sans notion de maladies systémiques ou de traitement par les corticostéroïdes: à propos d'un cas et revue de la literature

    Science.gov (United States)

    Chagou, Aniss; Rhanim, Abdelkarim; Berrady, Mohammed Ali; Lamrani, Moulay Omar; Oudghiri, Mohammed; Berrada, Mohammed Saleh; El Yaacoubi, Moradh

    2014-01-01

    Les lésions du tendon rotulien sont moins communes que celles du tendon quadricipital. Les lésions bilatérales sont encore plus rares et sont souvent associées à une notion de tendinopathie, d'injection de corticoïdes ou de maladies systémiques tels que le lupus érythémateux, l'ostéomalacie ou l'insuffisance rénale chronique. Nous rapportons le cas d'un patient de 26 ans victime d'une rupture bilatérale du tendon rotulien suite à une réception de saut. Le patient n'avait pas d'antécédents de tendinopathie ni de maladies systémiques. Le diagnostic a été suspecté devant une position anormalement haute des deux rotules avec une impossibilité d'extension active des deux jambes. L’échographie a confirmé le diagnostic. Le patient a été traité par la technique de laçage selon Judet protégée par un cadrage. La rupture bilatérale du tendon rotulien est rare. La plupart des patients rapportent une notion de maladie systémique ou un antécédents de chirurgie du genou. Nous rapportons le cas d'une lésion rare dans la littérature, une rupture bilatérale des tendons rotuliens sans notions de maladies auto-immunes ni de traitement avec des corticostéroïdes. Les lésions bilatérales présentent certaines particularités diagnostiques et thérapeutiques. En effet l'objectivation d'une rotule haute peut être rendu difficile par un aspect controlatéral semblable. Concernant le volet thérapeutique, deux difficultés sont à noter la première réside dans l'absence de référence comparative pour la hauteur patellaire. La deuxième difficulté est l'obligation de différer l'appui à 45 jours. Ce qui est contraignant pour le patient. La technique de laçage décrite par judet couplée à un cadrage provisoire protégeant la suture nous a donné des résultats satisfaisants. PMID:25667711

  6. Disposal of the radioactive effluents at the 'Commissariat a l'Energie Atomique'. Treatment leading to evacuation into a river; Probleme du rejet des residus radioactifs liquides au CEA. Traitements aboutissant a des rejets en riviere

    Energy Technology Data Exchange (ETDEWEB)

    Duhamel; Menoux; Candillon [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    to find out in loaded water, 10) Impot elements other than Sr{sup 90} are also studied. (author) [French] Le probleme du traitement des residus radioactifs liquides au CEA est envisage sous l'angle du rejet ultime en riviere dans des conditions optima permettant de satisfaire aux Normes de la protection. 2) A Saclay, ou l'on ne dispose que d'un etang ou l'eau ne se renouvelle pas, les liquides epures sont envoyes par camion citerne a Fontenay-aux-Roses, ou ils sont deverses provisoirement - dans les egouts - en attendant qu'un point de rejet en Seine ait ete determine. 3) Au Bouchet, les eaux residuaires de l'Usine de traitement de minerais d'urano-thorianite devront etre traitees en deux temps de facon a separer le radium dans une premiere phase, ce qui facilitera l'epuration au cours de la deuxieme phase. 4) En vue des futurs rejets a Marcoule, une etude a ete conduite a Saclay, sur des effluents synthetiques - type Marcoule - ayant pour but de mettre au point des procedes d'elimination selective du Sr d'une part, du Cs d'autre part, par coprecipitation. 5) Dans le cas general du rejet ultime en riviere, les problemes suivants sont successivement envisages: - predilution entre les bassins de stockage des eaux epurees et le fleuve; - mode d'injection dans le fleuve; - dilution dans le fleuve (etude prealable par traceurs); - evolution de l'activite dans les eaux du fleuve (adsorption par les organismes inertes ou vivants, contamination des berges); - incidence sur le choix d'un site; - dilution isotopique. 6) Ce dernier probleme est specialement detaille. 7) La teneur de l'eau en un element donne conditionne la dilution isotopique de son isotope radioactif. L'analyse decelant une carence, il est possible d'y suppleer par des rejets d'isotope stable. 8) Cette methode conduit en certains cas a des analyses delicates (en particulier dans le cas du {sup 90}Sr), la teneur en isotope

  7. From après-ski to après-tourism: the Alps in transition?

    Directory of Open Access Journals (Sweden)

    Philippe Bourdeau

    2009-12-01

    Full Text Available Winter sports occupy a prominent place in European tourism, not only because of their economic importance in mountainous areas but also due to their major symbolic significance in the "leisure civilisation". Yet the world of winter tourism is full of uncertainties connected with climate change and also with evolutions and structural breaks that call into question the development model on which it is based. This context of profound change gives us the opportunity to question the limits of the industrial model that has governed the development of the Alps for the practice of skiing and to examine alternative future scenarios to "all-out skiing" and even "all-out tourism".Les sports d’hiver occupent une place de premier plan dans le tourisme européen, non seulement du fait de leur poids économique dans les régions de montagne, mais aussi par leur forte dimension symbolique dans la « civilisation des loisirs ». Pourtant l’univers du tourisme hivernal est parcouru par de nombreuses incertitudes liées au changement climatique, mais aussi à des évolutions et des ruptures structurelles qui remettent en question le modèle de développement sur lequel il repose. Ce contexte de mutation permet d’interroger les limites du modèle industriel qui a présidé à l’aménagement des Alpes pour la pratique du ski et d’examiner des figures d’avenir alternatives au « tout ski » et même au « tout tourisme ».

  8. Traitement des diagraphies acoustiques. Première partie : application de techniques issues de l'intelligence artificielle au pointe des diagraphies acoustiques Full Waveform Acoustic Data Processing. Part One: an Artificial Intelligence Approach for the Picking of Waves on Full-Waveform Acoustic Data

    Directory of Open Access Journals (Sweden)

    Mari J. L.

    2006-11-01

    Full Text Available Les enregistrements des données acoustiques en champ total (fuit waveform ont conduit le géophysicien et le diagraphiste à utiliser des techniques de traitement du signal pour séparer les différentes ondes observées sur les enregistrements. L'une des tâches importantes du traitement des diagraphies acoustiques est le pointé des temps d'arrivée des différentes ondes enregistrées. Une démarche de type système expert a été utilisée pour mettre au point un algorithme multicanaux qui réalise le pointé des différentes ondes, à l'aide de règles faisant intervenir les caractéristiques ou attributs de chaque onde. Une onde est caractérisée par sa vitesse, sa fréquence, son amplitude et sa cohérence latérale. L'algorithme fournit un ensemble de logs accompagnés d'une estimation de la dispersion des mesures à chaque cote profondeur. Les logs fournis sont les logs de lenteur et les logs de fréquence. Les résultats obtenus sur un ensemble de diagraphies acoustiques enregistrées dans un puits vertical du Bassin parisien montrent que la dispersion des mesures reste faible en comparaison des pas d'échantillonnage en temps et profondeur. Les logs de dispersion peuvent aussi permettre de détecter des phénomènes physiques tels que caves, fractures, conversions d'ondes ou interférences, reliés à la lithologie. Dans une deuxième partie, nous montrerons différentes techniques de séparation d'ondes. La troisième partie illustrera, sur un cas particulier, l'utilisation des logs issus des diagraphies acoustiques pour caractériser les formations. The full waveforms recorded by an array of recievers in a borehole sonic tool contain a set of waves that can be fruitfully used to obtain detailed information about the nearborehole lithology and structure. The different waves that can be observed by full-waveform sonic data are described in this article. The main tools used in the recording of full-waveform data are then reviewed

  9. Plein feu sur l'irritation sensorielle et son traitement.

    OpenAIRE

    Pierard, Claudine; Pierard, Gérald

    2005-01-01

    Sensory irritation is directly bound to the concept of sensitive skin. A large proportion of the population, in particular young women, is affected. The reported symptoms are those of skin discomfort without any visible alteration of the skin. According to the subjects, the timing and the cutaneous sites, various perceptions occur, including pruritus, burning and stinging sensations. Sensory irritation is difficult to quantify because it remains subjective by essence. The condition is sometim...

  10. Environment. Biological processing of wastes; Environnement. Traitement biologique des dechets

    Energy Technology Data Exchange (ETDEWEB)

    Gourdon, R. [Institut National des Sciences Appliquees, INSA, Lab. d' Analyse Environnementale des Procedes et des Systemes Industriels, 69 - Villeurbanne (France)

    2001-01-01

    The main principle of the biological processing is the utilization of microbial activities by a control stimulation in order to decrease the wastes harmful effects, or by an energetic valorization. This paper deals with the solid wastes or the sludges. After a short presentation of the concerned wastes, their metabolism and their consequences, the author details two treatments: the composting (aerobic) and the methanization (anaerobic). The last part is devoted to the alcoholic fermentation and the industrial wastes (non agricultural) processing. (A.L.B.)

  11. Radioactive iodine ablation of Grave disease; Traitement ablatif par iode

    Energy Technology Data Exchange (ETDEWEB)

    Taieb, D.; Tessonnier, L.; Nwatsock, F.J.; Mundler, O. [Service central de biophysique et de medecine nucleaire, centre hospitalo-universitaire de la Timone, 264, rue Saint-Pierre, 13385 Marseille cedex 5, (France)

    2009-05-15

    The isotopic destruction by iodine of the thyroid body is an alternative to the surgery in the radical treatment of the Basedow disease, particularly for recurrent forms. Several strategies are possible in the use of iodine 131. between 2004 and 2008, 240 patients with a Basedow disease were treated in our service by an ablative activity of iodine 131 (555 MBq on average). the results are rather reproducible, that is to say a quasi constant hypothyroidism in the first three months. It appears important to underline that the ambulatory management of induced hypothyroidism is often unappropriated with too progressive introductions of LT4, leaving the patient in deep hypothyroidism during several weeks. The recurrences at short and middle term are very rare ( under 4%). A case of severe exophthalmos was observed. The other patients did not progressed with corticosteroids. The evolution of anti receptors autoantibodies of the TSH have been studying. to conclude, this kind of strategy is very efficient and reproducible, but needs an appropriate management of post therapy hypothyroidism, source of discomfort and potential morbidity. (N.C.)

  12. INHIBITION COGNITIVE, TRAITEMENT EMOTIONNEL IMPLICITE et TROUBLE DEPRESSIF MAJEUR

    OpenAIRE

    Gendry-Gohier, Bénédicte

    2011-01-01

    Major depressive disorder is characterized by impairments in memory, attention and executive functions, particularly the cognitive inhibition and in emotional regulation. The objective of this study was to evaluate the process of emotional processing in major depressive disorder byfocusing on cognitive inhibition and the implicit treatment of emotional information. In a first experiment, we evaluated the ability of cognitive inhibition in a population of twenty patients suffering from major d...

  13. Structures spatio-linguistiques du texte : traitements formels et cognitifs

    OpenAIRE

    Garcia-Debanc, Claudine

    2005-01-01

    Ce texte est un rapport de fin de recherche issu de l'ACI cognitique. Abstract The page, whether on screen or on paper, is a particularly appropriate object for the study of spatial cognition. It constitutes a well circumscribed space, constructed and regulated by a set of conventions. The term “Spatio-linguistic text structures” is used to refer to the processing instructions inscribed in the text in the form of lexical-syntactic items, typographic marks (dashes, bold, italics, different ...

  14. Automation on computer of the partial area method in the analysis of resonances induced by 'S' neutrons 2. with an interference term and extension of the method to the treatment of multi resonances (1963); Automatisation sur ordinateur de la methode des aires partielles dans l'analyse des resonances induites par les neutrons ''S''. 2, avec terme d'interference et extension de la methode au traitement des multiresonances (1963)

    Energy Technology Data Exchange (ETDEWEB)

    Bianchi, G.; Corge, C.R. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1963-07-01

    This report deals with the numerical analysis on an I.B.M. 7090 computer of transmission resonances induced by 's' wave neutrons in time of flight experiments. The analysis method used is the partial area one. In this second part the interference term is taken into account. Modifications have been made in the programs and subroutines described in the first part, to determine the resonant transmissions from experimental raw data, and the relating partial areas. Also programs and subroutines are thoroughly described, which estimate the resonance parameters. The field of the partial area method has been extended to cover the case where several resonances have to be treated simultaneously, provided they do not interfere. (authors) [French] Le pretent rapport a pour objet l'analyse numerique sur ordinateur I.B.M. 7090 des resonances dues aux neutrons ''s'' dans les experiences de transmission par temps de vol, la methode d'analyse utilisee etant la methode dea aires partielles. Dans cette deuxieme partie il a ete tenu compte du terme d'interference. On y trouvera une description des amenagements apportes aux programmes et sous-programmes decrits dans la premiere partie pour determiner les transmissions interfero-resonnantes a partir des donnees experimentales brutes et les aires partielles afferentes. Sont egalement decrits les programmes et sous-programmes necessaires au calcul des parametres caracteristiques des resonances. Le domaine d'application de la methode a ete etendu au traitement simultane de plusieurs resonances groupees n'interferant pas entre elles. (auteurs)

  15. Experimental Design: Application to the Development of a Treatment to Inhibit the Deposition of Barium Sulfate Liable to Be Formed in Enhanced Oil Recovery by Waterflooding Planification d'expériences : application à la mise au point d'un traitement inhibiteur du depôt de sulfate de baryum susceptible de se former en récupération assistée du pétrole par injection d'eau

    Directory of Open Access Journals (Sweden)

    Roque C.

    2006-11-01

    Full Text Available For technical and economic reasons, waterflooding is the most widely-used method in enhanced oil recovery [1]. In many situations, unfortunately, the formation water is incompatible with the injection water. The deposits and corrosion induced by the various reactions of this incompatibility cause irreversible damage, which is especially dangerous for the reservoir rock and the downhole and surface production facilities. This study is concerned exclusively with barium sulfate deposits liable to occur in surface production facilities by the mixing of injection water loaded with sulfate (1300 mg. 1 to the power of (-1 with a formation water with a high barium concentration (1200 mg. 1 to the power of (-1 [2]. Pour des raisons techniques et économiques, l'injection d'eau dans les réservoirs est la méthode la plus employée dans la récupération du pétrole. Malheureusement, dans bien des cas, l'eau en place dans le gisement est incompatible avec l'eau injectée. Les dépôts et les corrosions causés par les diverses réactions physico-chimiques de cette incompatibilité provoquent des dégradations irréversibles particulièrement dangereuses pour les installations de production de fond comme de surface et quelquefois pour la roche réservoir elle-même. Dans le cadre des travaux de recherche relatifs à l'inhibition des dépôts de sulfate sur le champ algérien de Tin Fouyé Tabankort, cette étude a eu pour objectif de sélectionner et d'adapter aux conditions spécifiques de la production un traitement de prévention des dépôts par injection d'un agent inhibiteur. Elle concerne exclusivement les dépôts de sulfate de baryum pouvant apparaître dans les installations de production par mélange d'eau d'injection très chargée en ion sulfate (1300 mg. 1 puissance(-1 avec une eau de gisement très concentrée en élément baryum (1200 mg. 1 puissance(-1. Une méthode expérimentale au laboratoire, faisant appel à des mesures de type

  16. Les réseaux sociaux et l’échange entre l’homme politique et les internautes : le cas de Facebook après les élections présidentielles en France Social Networks and the Exchange Between Politicians and Surfers: Facebook and the presidential post elections in France

    OpenAIRE

    Galia Yanoshevsky

    2010-01-01

    A travers l’analyse des interactions entre hommes politiques et internautes sur Facebook après les élections présidentielles de 2007 en France, cet article vise à montrer comment les réseaux sociaux sont exploités par les deux parties. Au départ un réseau décentralisé qui lie les gens sans intervention politico-hiérarchique, Facebook est mobilisé par les hommes politiques au service de leur besoins. Quelles en sont les conséquences pour la sphère publique : s’agit-il d’un outil qui permet à l...

  17. Le fluvalinate appliqué sur pommiers en pleine floraison : contamination des abeilles butineuses et des produits de la ruche

    OpenAIRE

    Haouar, M; De Cormis, L; Rey, J.

    1990-01-01

    Les auteurs se proposent d’étudier l’incidence, sur les abeilles butineuses et les produits de la ruche, d’un traitement au fluvalinate d’un verger de pommiers en pleine floraison. Aux doses recommandées pour un traitement insecticide à savoir 144 g/ha, on retrouvait 41,3 μg/g dans les fleurs de pommiers immédiatement après le traitement. Onze jours plus tard on en retrouvait encore 34,4 μg/g, soit plus de 83% du dépôt initial (tableau I). Dans les feuilles, le dépôt initial a été évalué ...

  18. Progrès et développement économique au Chili durant la République conservatrice (1830-1861) 

    OpenAIRE

    Louis, Jérôme

    2015-01-01

    Les conservateurs l’emportent sur les libéraux après la bataille de Lircay en 1830. La constitution portalienne et le triomphe du Chili contre la confédération péruano-bolivienne (1836-1839) permettent au pays de contrôler le Pacifique sud. Le port de Valparaiso se développe. Le Chili s’insère dans l’économie capitaliste mondiale par le biais de ses exportations minières et agricoles, mais le pays est endetté auprès de la Grande-Bretagne en raison d’un emprunt de 9 millions de pesos contracté...

  19. L’impossible musée ? 1989-2005, le musée national des Prisons

    Directory of Open Access Journals (Sweden)

    Catherine Prade

    2012-05-01

    Full Text Available En 1996, une jeune étudiante de l’université Paris VIII présentait à un groupe de conservateurs son mémoire de maîtrise scientifique et technique de médiation culturelle, mémoire qu’elle avait intitulé Le musée des prisons, l’impossible musée ? en claire référence à L’impossible prison, ouvrage publié en 1980 après le fameux débat organisé par Michelle Perrot entre Michel Foucault et Jacques Léonard, le philosophe et l’historien…Impossible musée… dont la genèse et l’accomplissement reposent s...

  20. Processing Pp and Ps Wave in Multicomponent Sea-Floor Data for Azimuthal Anisotropy : Theory and Overview Traitement des données multicomposantes en ondes PP et PS sur les fonds marins, en termes d'anisotropie azimutale : théorie et vue d'ensemble

    Directory of Open Access Journals (Sweden)

    Li X. Y.

    2006-12-01

    Full Text Available Assuming fracture-induced azimuthal anisotropy, we review the theory and develop processing methods for recovering the fracture orientation and density from multicomponent sea-floor data. The azimuthal variations in PP amplitude, normal move-out velocity, and interval move-out show elliptical variations in an azimuthally anisotropic medium. This can be used to determine the fracture strike of the medium and has been verified from real data. However, the P-wave effects only occur with multi-azimuths, and are often complicated by other factors. This limits the application of P-wave analysis to some extent. Analysis of PS waves may thus prove to be beneficial. For near vertical propagating PS waves, the polarization and time delay of the shear-waves provide a direct measurement of the fracture orientation and intensity. For a 2D acquisition where the survey line is along the receiver cable, an optimum method is proposed for determining the fracture strike from the polarization azimuth of the fast shear-wave. The method uses rotation analysis and assumes that the fast and slow shear-waves have similar waveforms. For a 3D cross geometry where the survey line is perpendicular to the receiver cable, two deterministic methods are proposed. The first one is based on the polarity change and amplitude dimming in the azimuthal gathers of the transverse-geophone component. The second one involves a rotation of orthogonal pairs of source-receiver azimuthal gathers. The determined polarization azimuth can then be used to separate the fast and slow shear waves in the inline-shooting gathers for time-delay estimation. Dans l'hypothèse d'une anisotropie azimutale induite par les fractures, nous révisons la théorie et développons des méthodes de traitement pour retrouver l'orientation et la densité de la fracture à partir de données sur les fonds sous-marins à composantes multiples. Les variations azimutales d'amplitude PP, la vitesse de move-out et le

  1. Effects of silviculture treatments on vegetation after fire in Pinus halepensis Mill. woodlands (SE Spain)

    OpenAIRE

    Jorge De Las Heras,; González-Ochoa, Ana; López-Serrano, Francisco; Simarro, María

    2004-01-01

    Effets des traitements sylvicoles sur la végétation après un feu dans des forêts de Pinus halepensis Mill. (sud-est de l'Espagne). En août 1994, deux grands feux se sont produits dans le sud-est de l'Espagne et ont brûlé 44000 ha de forêt de Pinus halepensis Mill. adultes. Après le feu, il y a eu une régénération intense de la forêt qui a formé des bosquets touffus de plantules. On a alors procédé à des études sur la régénération naturelle du pin en appliquant différents traitements sylvicole...

  2. Les réseaux sociaux et l’échange entre l’homme politique et les internautes : le cas de Facebook après les élections présidentielles en France Social Networks and the Exchange Between Politicians and Surfers: Facebook and the presidential post elections in France

    Directory of Open Access Journals (Sweden)

    Galia Yanoshevsky

    2010-10-01

    Full Text Available A travers l’analyse des interactions entre hommes politiques et internautes sur Facebook après les élections présidentielles de 2007 en France, cet article vise à montrer comment les réseaux sociaux sont exploités par les deux parties. Au départ un réseau décentralisé qui lie les gens sans intervention politico-hiérarchique, Facebook est mobilisé par les hommes politiques au service de leur besoins. Quelles en sont les conséquences pour la sphère publique : s’agit-il d’un outil qui permet à l’internaute de déjouer les usages de marketing politique qu’en fait l’homme politique ?The purpose of this article is to show how social networks, and more specifically Facebook, are used by politicians and their supporters. This is achieved through a detailed analysis of exchange of posts between politicians and surfers in the period following the presidential election campaigns in France of 2007. It is shown how politicians take advantage of Facebook, despite its initially being a decentralized social network, connecting people without a political or hierarchic purpose. The article attempts to show some of the consequences of such an exploitation of a public network for the public sphere and asks how much leverage there is for the surfers/citizens in moderating political marketing on Facebook.

  3. Conservation et disparition des repères de crue – Exemple des repères apposés après la crue de 1930 en Lot-et-Garonne et dans le sud du Tarn

    Directory of Open Access Journals (Sweden)

    François Gazelle

    2009-04-01

    Full Text Available Pour matérialiser les niveaux atteints par les crues importantes en des points significatifs, et pour en conserver la mémoire à toutes fins utiles, la loi BACHELOT de juillet 2003 fait obligation aux mairies ou services d'État de mettre en place des repères visibles, pratique qui n'est pas nouvelle mais qui tendait à s'estomper d'autant qu'elle n'était pas réglementaire. On peut s'interroger sur la conservation de ces repères au fil des décennies. À ce titre, les auteurs ont exploité les données archivistiques et effectué des enquêtes de terrain pour appréhender la présence ou l'absence de repères placés après la crue de 1930 en deux secteurs du Sud-Ouest de la France, et saisir les causes des disparitions recensées.In order to show the levels reached by major flood events at significant points, and in order to record the information for future reference, the law promoted by BACHELOT in July 2003 places an obligation on municipal councils and state-run bodies to put in place visible markers, a practice which is not new but which had tended to die out while it was not a statutory requirement. It is reasonable to raise the question of the conservation of these markers over the decades. With this in mind, the authors made use of archival data and carried out field investigations in order to determine the presence or absence of markers put in place after the flood of 1930 in two areas of south-western France, and to establish the causes of the disappearances that they found.

  4. Traitement des diagraphies acoustiques. Troisième partie : caractérisation d'un réservoir par diagraphies acoustiques obtenues avec un outil dipolaire Full-Waveform Acoustic Data Processing. Part Three: Reservoir Characterisation Using Acoustic Logs Obtained with the Dipole Sonic Imaging Tool

    Directory of Open Access Journals (Sweden)

    Wicquart E.

    2006-11-01

    Full Text Available En formation lente, l'utilisation d'un outil acoustique équipé d'émetteurs et de récepteurs dipolaires permet d'accéder à la lenteur S de la formation. Nous montrons comment un tel outil peut être utilisé pour caractériser un réservoir en formation lente. Le pointé des premières arrivées des différentes ondes composant un enregistrement acoustique en champ total permet d'accéder aux logs acoustiques classiques (lenteur, fréquence, atténuation ainsi qu'aux logs de dispersion de mesure qui leur sont associés. Ces logs conduisent à des logs de paramètres mécaniques notamment au coefficient de Poisson. Dans le cas du puits étudié traversant une formation argilo-gréseuse, le log du coefficient de Poisson et le log de fréquence des ondes de Stoneley sont utilisés comme indicateur lithologique d'argilosité et de présence d'hydrocarbures (gaz. Après correction d'argilosité, les logs de lenteur en onde compression et de cisaillement sont utilisés en combinaison avec un log densité de type Gardner pour estimer les paramètres pétrophysiques de la formation (indices de porosité et de saturation en gaz. Les résultats obtenus sont comparés à ceux fournis par l'analyse de logs classiques (neutron, densité. In slow formations, in which the velocity of the compression wave in mud is greater than the velocity of the shear wave in the formation, the slowness S of the formation can be determined only very indirectly (using Stoneley waves with a conventional monopole tool. For such formations, the use of a dipole tool makes it easier to gain access to this measurement and to obtain more complete information about the formation. This article shows how such a tool can be used for characterizing a slow-formation reservoir. The tool has a monopole transmitter capable of emitting low frequencies so as to favor interface modes and, at high frequencies, head waves (P refraction in the formation. The tool has two dipole transmitters

  5. Chernobyl, 16 years later; Tchernobyl, 16 ans apres

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-04-01

    This document on the Chernobyl site evolution is constituted around four main questions. What about the future of the Chernobyl site, the damaged reactor and the ''sarcophagus'' constructed around the reactor? What about the sanitary consequences of the accident on the liquidators asked to blot out the radiation and the around people exposed to radiation? What about the contaminated land around the power plant and their management? Concerning the France, what were the ''radioactive cloud'' sanitary consequences? (A.L.B.)

  6. Chernobyl, after the apocalypse; Tchernobyl, apres l'apocalypse

    Energy Technology Data Exchange (ETDEWEB)

    Coumarianos, Ph

    2000-07-01

    This document recalls the human aspects of the Tchernobyl reactor accident threw a series of testimonies, from the power plant head and engineers, to the firemen and people from the surrounding population. (J.S.)

  7. Acid Rain Data at Yokohama, Japan (Apr. 2003-Aug. 2004)

    OpenAIRE

    Murayama, Haruta

    2005-01-01

    Rain samples were collected adequately at the center of Yokohama city from April 2003 to August 2004. Total numbers of samples were 214. pH values and electric conductivity (E.G.) were measured immediately after catched samples and then chemical species were analyzed. This report is contained all observed data. Frequency of acid rain(pH

  8. L'OPTIQUE QUANTIQUE ATOMIQUE : APRES LES BOSONS, LES FERMIONS

    OpenAIRE

    Westbrook, Christoph I; Aspect, Alain; Boiron, Denis

    2007-01-01

    Les avancées de l'optique atomique permettent de plus en plus de rapprochements avec l'optique traditionnelle ; les expériences fondatrices de corrélation de photons en optique quantique ont trouvé leurs analogues atomiques. L'observation récente du groupement et dégroupement d'atomes ouvre des perspectives sur des observations de systèmes fortement corrélés d'un grand nombre de particules.

  9. Thyroid tumors after irradiation; Tumeurs de la thyroide apres irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Schlumberger, M. [Centre de Lutte Contre le Cancer Gustave-Roussy, 94 - Villejuif (France)

    1995-12-31

    Epidemiological studies have shown an increased incidence of thyroid tumors after external irradiation during childhood. These studies have shown a long latency and have pointed out risk factors, related either to the subject (young age, female sex) or to the radiation (dose, fractionation, protection). Irradiation by Iodine 131 in adulthood does not seen to increase the risk of thyroid tumor but in childhood data are too scarce to allow any conclusion. Similarly, the risks following low radiation doses and/or protected radiation exposure are still matter of debate. (author). 41 refs., 5 tabs., 1 fig.

  10. Chernobyl, 12 years later; Tchernobyl, douze ans apres

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-04-01

    This report draws an account of the consequences of Chernobyl accident 12 years after the disaster. It is made up of 7 chapters whose titles are: (1) Some figures about Chernobyl accident, (2) The Chernobyl nuclear power plant, (3) Sanitary consequences of Chernobyl accident, (4) The management of contaminated lands, (5) The impact in France of Chernobyl fallout, (6) The Franco-German cooperation, and (7) Glossary.

  11. Chernobyl, 14 years later; Tchernobyl, 14 ans apres

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report draws an account of the consequences of Chernobyl accident 14 years after the disaster. It is made up of 8 chapters whose titles are: (1) Some figures about Chernobyl accident, (2) Chernobyl nuclear power plant, (3)Sanitary consequences of Chernobyl accident, (4) The management of contaminated lands, (5) The impact in France of Chernobyl fallout, (6) International cooperation, (7) More information about Chernobyl and (8) Glossary.

  12. Chernobyl, 13 years after; Tchernobyl, 13 ans apres

    Energy Technology Data Exchange (ETDEWEB)

    Regniault-Lacharme, Mireille; Metivier, Henri [Inst. de Protection et de Surete Nucleaire, CEA Centre d' Etudes de Fontenay-aux-Roses, 92 (France)

    1999-04-01

    This is an annual report, regularly issued by IPSN, that presents the ecological and health consequences of the Chernobyl Nuclear Accident. The present status of the Chernobyl Nuclear Plant, which Ukraine engaged to stop definitively in year 2000, is summarized. The only reactor unit now in operation is Chernobylsk-3 Reactor which poses two safety questions: evolution of cracks in part of the tubing and behaviour of the pressure tubes. Although, some improvements in the RBMK reactor types were introduced, problems remain that make IPSN to stress the requirement of stopping this NPP completely. In the contaminated territories surrounding Chernobyl incidence rate of infant thyroid cancers continues to grow, reaching values 10 to 100 times higher than the natural rate. In France the IPSN analyzed 60,000 records carried out in 17 sites during May 1986 and April 1989. It was estimated that the individual dose received during 60 years (1986-2046) by the inhabitants of the most affected zone (eastern France) is lower than 1.5 mSv, a value lower than 1% of the natural cosmic and telluric radioactivity exposure for the same period. For the persons assumed to live in the most attacked forests (from eastern France) and nourishing daily with venison and mushrooms the highest estimate is 1 mSv a year. Concerning the 'hot spots', identified in mountains by IPSN and CRIIRAD, the doses received by excursionists are around 0.015 mSv. For an average inhabitant of the country the dose piled up in the thyroid due to iodine-131 fallout is estimated to 0.5-2 mSv for an adult and 6.5-16 mSv for an infant. These doses are 100 to 1000 times lower than the ones to which the infants living in the neighbourhood of Chernobyl are exposed to. The contents of the report is displayed in the following six chapters: 1. Chernobyl in some figures; 2. The 'sarcophagus' and the reactors of the Chernobyl NPP; 3. Health consequences of the Chernobyl accident;. 4. The impact of Chernobyl fallout in France; 5. Chernobyl's environment and the management of contaminated territories.; 6. The French-German initiative for Chernobyl.

  13. Extended Station Blackout Coping Capabilities of APR1400

    OpenAIRE

    Sang-Won Lee; Tae Hyub Hong; Mi-Ro Seo; Young-Seung Lee; Hyeong-Taek Kim

    2014-01-01

    The Fukushima Dai-ichi nuclear power plant accident shows that an extreme natural disaster can prevent the proper restoration of electric power for several days, so-called extended SBO. In Korea, the government and industry performed comprehensive special safety inspections on all domestic nuclear power plants against beyond design bases external events. One of the safety improvement action items related to the extended SBO is installation of external water injection provision and equipment t...

  14. Market Review RE Market Apr.10~20

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ RE carbonate in Baotou was in tight supply due to the strong demand.Prices of Nd and Pr products kept on rising recently.Affected by the price rising of SmEuGd concentrate in Baotou,price of europium went upward.

  15. Le facteur soudanais, avant et après

    OpenAIRE

    Marchal, Roland

    2002-01-01

    Le 11 septembre 2001 reposait la question de la nature du régime soudanais et des étranges amitiés qu’il a cultivées depuis son arrivée au pouvoir, le 30 juin 1989. En effet, les États occidentaux savaient que le chef d’Al- Qaida, Oussama Ben Laden, avait longtemps résidé au Soudan – de 1991 à 1996 – parmi bien d’autres militants fondamentalistes, et que les liens avec les courants les plus durs de l’islamisme s’étaient poursuivis. De nombreux observateurs auguraient alors une forte réacti...

  16. Zorn: Avant/Après/Passé

    Directory of Open Access Journals (Sweden)

    John Lowell Brackett

    2012-06-01

    Full Text Available Witold Wachowski’s brief exchange with John Zorn provides us with many valuable insights relating to the composer’s aesthetic. Zorn’s professed antipathy towards audiences, his faith in the creative instinct of the “artist,” and his belief in the transcendental nature of musical works (as a gateway into a world of “truth” and “beauty” are all refrains commonly encountered in many interviews with the composer. Given the fact that Zorn emphasizes these themes in his very short interview with Wachowski, we can assume that these ideas form the core of Zorn’s musical and artistic aesthetic. For any person with even a basic knowledge of Western aesthetic traditions, however, these same aesthetic features and positions characterize musical institutions common to the Western art tradition, particularly the “romantic” ideal of music and composers that developed in the nineteenth century. Philosophers (most notably Hegel and Kant along with music critics and composers (such as Friedrich Schiller, E.T.A. Hoffmann, Friedrich Schlegel, Robert Schumann, and Eduard Hanslick all contributed to the development of a romantic musical aesthetic in the nineteenth century that emphasized the role of the artist (as a “genius” or “god-like” who created “works” that – through purely musical relations that exist irregardless of the listener’s abilities – reveal hidden worlds of truth and beauty, worlds far-removed from the humdrum concerns of daily existence. Given the close (nearly one-to-one correspondences between Zorn and aestheticians/philosophers of the nineteenth century, one could make the argument that Zorn holds a “romantic” view of music and art.

  17. Chernobyl, fifteen years after; Tchernobyl, 15 ans apres

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-04-01

    This work has been constituted around four questions: the future of the Chernobyl site, the damaged reactor, and the sarcophagus around it; the health consequences of the accident on the persons that have worked on the damaged reactor and on the population in the countries the most exposed to fallout,; the situation of contaminated territories around the power plant and their management today; the last question concerns especially the France with the consequences of the radioactive cloud and what we know about the health risks induced by this event. (N.C.)

  18. ABSTRACTS( Vol. 26 No. 2 Apr. 2012)

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Fa Lin, Wang Lei, Zheng Yajuan, Zhang Qi and Zhang Xiaohu. The application of acoustics in oil logging and geophysical exploration. PI. 2012,26 (2): 1-6 By using the method of acoustic-electric analogue, this paper sets up the equivalent circuits of acoustic transducer, and gives the relationship between the acoustic-signal radiated by the source-transducer and the driving-voltage signal and that between the acoustic-signal and electric-signal converted from the receiver-transducer. This paper employs the convolution of the driving-voltage signal with the electric-acoustic impulse response of the source-transducer to replace some assumed acoustic-source functions adopted in previouly published literature on acoustic logging, such as Tsang wavelet and so on. In this paper the concept and theory of signal transmission is used to analyze the total acoustic- logging process, and the acoustic-logging transmission network model is set up. This model sets up the theoretical basis for accurate measurements of propagation speed, phase, amplitude and frequency information of acoustic-logging signal. The development of a new device, Kaiser in-situ stress system is introduced. This device is designed to measure in-situ stresses via detected acoustic emissions caused by the Kaiser effect in rocks. The system provides a technical means for both the economic and efficient evaluation of the three principal stresses in rocks. This is useful to assess the in-situ stress field in oil and gas reservoirs and to predict natural geology hazard. A new algorithm of inversion oil reservoir by using logging data and seismic exploration date is also described.

  19. Two years after the storms; 2 ans apres les tempetes

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-12-01

    This document takes stock on the power distribution repair, two years after the storms of december 1999 in France. It also presents the new organization (FIRE) developed to face such natural or accidental disasters. (A.L.B.)

  20. Modification des propriétés physico-chimiques de l'amidon par procédés hydrothermiques : Contribution à l'étude des transferts couplés chaleur-masse

    OpenAIRE

    Bahrani, Seyed Amir

    2012-01-01

    L'amidon, biopolymère de réserve, composant majeur des céréales et des plantes de grande culture, trouve de nombreuses applications industrielles après transformation hydrothermique. L'objectif de la thèse est d'étudier les modifications des propriétés structurales et fonctionnelles de l'amidon de maïs standard modifié par traitement physique, de type hydrothermique à l'aide de trois procédés. L'intensification des traitements, dans un contexte où le développement durable apparaît comme une p...

  1. Consequences immediates et differees de periodes de secheresse estivale sur le developpement de jeunes noyers (Juglans regia L., cv Pedro ): dynamique de croissance et dormance automno-hivernale des bourgeons

    OpenAIRE

    Dreyer, Erwin; MAUGET, Jean-Claude

    1986-01-01

    De jeunes noyers (Juglans regia L. cv « Pedro ») de 3 ans, cultivés dans des pots de 120 l en conditions naturelles, ont été soumis à des contraintes hydriques intenses mais de courte durée (2-3 semaines). Deux époques de traitement ont été retenues : au printemps, à la fin de la 1re vague d’allongement des pousses de l’année, et, à la fin de l’été, après l’arrêt de la 2e vague d’allongement. Ces traitements ont eu des effets : - immédiats (arrêt de croissance, réduction de surface foliai...

  2. Evaluation de l'imagerie par résonance magnétique nucléaire pour la caractérisation de la répartition spatiale de l'eau dans un milieu poreux

    OpenAIRE

    HAUTEFEUILLE, Laurent; AMINE NYEL, Mohamed; LABORATOIRE DES MATERIAUX ET DES STRUCTURES DU GENIE CIVIL - LMSGC; LABORATOIRE CENTRAL DES PONTS ET CHAUSSEES - LCPC

    2002-01-01

    Les objectifs du stage étaient, d'une part, de développer une boîte à outils de traitement informatique des images obtenues grâce à l'imageur par résonance magnétique, et, d'autre part, d'identifier le type d'informations que l'on peut tirer de ces images après traitement. Pour vérifier la validité de nos méthodes et de nos outils informatiques, nous avons simulé par voie numérique des images du même type que celles obtenues grâce à l'IRM pour des empilements modèles parfaitement caractérisés...

  3. La politique française à l’égard de l’émigration juive polonaise de l’immédiat après-guerre French policy towards the Exodus of Polish Jews in the Aftermath of World War II

    Directory of Open Access Journals (Sweden)

    Julia Maspero

    2012-03-01

    Full Text Available Cet article traite de la politique française à l’égard de l’émigration juive polonaise de l’immédiat après-guerre. Cette politique se définit en France et dans les zones françaises d’occupation en Allemagne et en Autriche. Comme le montre l’existence d’une catégorie « DP juifs » dans les recensements ainsi que la mise en place de camps DP juifs et de kibboutzim, les autorités françaises considéraient les réfugiés juifs de l’Est comme un groupe à part. Cet article montre le rôle important, pour atteindre la France et l’Italie puis la Palestine, joué par les zones françaises d’occupation de part leur position géographique cruciale (relations diplomatiques avec les Américains et Italiens, politique de refoulement…. La France a quant à elle été pour ces réfugiés bien plus un pays de transit vers les Amériques et la Palestine qu’un pays d’accueil, comme on peut le constater à travers les tentatives de contrôle des flux : mise en place d’un accord sur l’admission en transit de 8 000 réfugiés juifs de Pologne (conditions de l’accord, position des différents ministères français et des organisations juives en France… et refoulement vers l’Allemagne.This article is about the French policy towards Polish Jews emigration in the aftermath of WWII. This policy has been defined in France and in French zones of occupation in Germany and Austria. As shown by the existence of a “Jewish DPs” category in the census and the setting up of Jewish DP camps and kibbutzim, French authorities considered Jewish refugees from Eastern Europe as a separate group. This article shows the important role played by the French zones in the path followed by Jewish refugees in order to reach France and Italy and then Palestine (diplomatic relations with Americans and Italians, the policy of expulsion. It also shows that France has been for these refugees more a transit country to Americas and Palestine than

  4. Aspects architecturaux de la transformation de Hà Nội après le Đổi mới (1986 : contradictions, phantasmes, espoirs Architectural Aspects of Hà Nội’s Transformation after Đổi mới (1986: Contradictions, Fantasies, Hopes

    Directory of Open Access Journals (Sweden)

    Heinz Schütte

    2009-06-01

    Full Text Available Depuis le Đổi mới, c’est-à-dire depuis la progressive libéralisation de l’économie vietnamienne, Hà Nội a connu de profondes mutations. Après des décennies de guerres et l’échec de la mise en place d’un système économique socialiste, des changements radicaux se sont opérés dans le paysage urbain de Hà Nội. Ces modifications sont visibles dans le bâti urbain pour tout visiteur de la ville. Cet article tente de montrer que, contrairement aux apparences, ce processus de transformation n’est ni aléatoire ni chaotique, mais qu’il suit une logique historique et culturelle, et qu’il ne peut être réduit à un phénomène de globalisation. Les riches villas du Lac de l’Ouest sont représentatives des valeurs d’une nouvelle classe sociale qui a émergé suite au Đổi mới. Les mutations architecturales de la ville reflètent les changements sociaux : la ville tend à devenir un lieu de consommation alors que les riches villas se bâtissent à sa périphérie, bouleversant ainsi l’organisation de l’espace traditionnel.Ever since Đổi mới, the arrival of capitalist market forms, and the evolution of corresponding social relations, Hà Nội has undergone a dramatic upheaval. After revolutions, wars and the failure of centralized economy, we are currently witnessing a radical change from pre-modernity to the modernity of a globalized age. The consequences are perceptible when strolling through Hà Nội’s streets and talking to the capital’s inhabitants. This article attempts to demonstrate that the process of transformation is not as random or chaotic, as it may seem, but that it follows a logic that can be historically categorized. The posh new villas on West Lake and their upwardly mobile owners represent new, syncretic values; the origins of family businesses are carefully hidden; the individual activities in the 36 guild streets of the Old Quarter; these are all testaments to change that

  5. Epidemiological analysis on virus etiology of acute respiratory infection during Oct 2010 and Apr 2011 in Beijing%北京地区2010年10月至2011年4月急性呼吸道感染病毒流行特征分析

    Institute of Scientific and Technical Information of China (English)

    黄芳; 石伟先; 崔淑娟; 钱海坤; Yan Li; 邓瑛

    2011-01-01

    spectrum were influenza A virus, respiratory syncytial virus and adenovirus. The positive ratio for the virus detection was distributed timely. It was high from Oct to Apr of next year and it as maximum in Nov (93.75%) while it was dropped down from Mar. The dominated viruses were different in different months and in different age groups. For the 0 ~ 5 age groups, the respiratory syncytial virus was maximum and for 5 ~ 15 age group adenovirus was found largest while for all the other age groups more than 15 years old influenza A was the dominated virus. Conclusions Influenza virus, respiratory syncytial virus, adenovirus were the main pathogens leading to acute respiratory infection during winter and spring in Beijing and the pathogens have specific epidemiology according to the ages and months.

  6. Comportement du sol au labour : methode d'analyse et evaluation des consequences de l'etat initial du sol sur l'etat transforme par le labour

    OpenAIRE

    Coulomb, I.; Caneill, J; Manichon, H

    1993-01-01

    Nous étudions expérimentalement l’effet de l’état structural de la couche labourée avant labour sur son état après labour, en sol limono-argileux dans le domaine hydrique de comportement fragile du sol. Nous comparons deux traitements caractérisés par des états avant labour continus et compacts induits par compactage ou fragmentaires. On distingue deux types d’états compactés en fonction de la date de tassement (1 semaine avant labour, 1 mois avant labour). Trois classes de vitesses de labour...

  7. Thromboses veineuses profondes distales symptomatiques : un dilemme diagnostique et thérapeutique

    OpenAIRE

    Paris, Samuel

    2006-01-01

    La thrombose veineuse profonde (TVP) distale est une pathologie relativement fréquente. Sa prise en charge n'est pas uniforme (recherche par ultrasonographie veineuse par compression (CUS), traitement par anticoagulation). Après deux présentations de cas cliniques et un rappel anatomique, nous avons revu la littérature concernant son histoire naturelle, son épidémiologie et les approches diagnostiques et thérapeutiques existantes. En cas de suspicion clinique de TVP, plusieurs grandes études ...

  8. Thromboses veineuses profondes distales symptomatiques: un dilemme diagnostique et thérapeutique

    OpenAIRE

    Paris, Samuel; Bounameaux, Henri

    2006-01-01

    La prévalence de la thrombose veineuse profonde (TVP) distale varie de 2-9% dans une population symptomatique. Sa prise en charge n’est pas uniforme (recherche par ultrasonographie veineuse par compression (CUS), traitement par anticoagulation). Après deux présentations de cas cliniques et un rappel anatomique, nous avons revu la littérature concernant son histoire naturelle, son épidémiologie et les approches diagnostiques et thérapeutiques existantes. En cas de suspicion clinique de TVP, pl...

  9. Les séries figées dans Le traité de stylistique de Charles Bally (1865-1947)

    OpenAIRE

    Brigitte Lépinette

    2013-01-01

    Cet article contextualise dans Le traité de stylistique ([Heidelberg, 1909 et 1921] 1951) de Charles Bally le traitement des séries figées, question qui, en particulier, après les recherches sur la combinatoire sémantico-lexicale d’Igor Mel’čuk et les travaux syntaxico-sémantiques, de base distributionaliste, de Maurice Gross spécialement, a donné lieu, de nos jours, à une littérature linguistique aussi bien quantitativement que qualitativement importante. Avant ces derniers auteurs, Bally...

  10. la progesterone et la grossesse

    OpenAIRE

    HAMDANT, .DJ; DOUCH, .F; OUAKKA, .A; TABET DERREZ, .I; .BOUARICHA, .N

    2010-01-01

    Les progestatifs au cours de la grossesse restent largement indiquer pour prévenir ou traiter une menace d'avortement spontané soit la prévention et traitement des menaces d'accouchement prématuré. D'après les resultats de notre travail, on a constaté que les effets de la progestérone sont minimes sur la durée de grossesse et la modalité d'accouchement. La prescription de progestérone dans un but thérapeutique durant la grossesse garde sa place en montrant son effecaci...

  11. Multiplication de l'espèce : aspects fondamentaux et appliqués

    OpenAIRE

    Danthu, P.; Roussel, J; Neffati, M

    2013-01-01

    Le tégument des graines d'A. raddiana a une structure anatomique typique des légumineuses qui induit une forte inhibition de la germination. Cela implique qu'une scarification naturelle (chocs, feu) ou artificielle (traitement mécanique ou chimique) du tégument est nécessaire pour permettre l'imbibition et la germination des graines. Cette forte inhibition tégumentaire explique aussi que les graines restent intactes après passage dans le tractus digestif des animaux sauvages ou domestiques qu...

  12. Moteurs de recherche et restitution de l'information dans les grandes entreprises : l'exemple du portail Cyberthèque de la Direction des Systèmes d'Information de la Société Générale

    OpenAIRE

    Ivanciuc Deniau, Alina

    2003-01-01

    Après avoir replacé les moteurs de recherche dans le contexte de la recherche d'information et des langages documentaires (notamment le thésaurus), compte tenu des mutations de ces dernières années (taxonomies, ontologies, Topic Maps), la première partie du mémoire se propose de décrire le fonctionnement de ces outils issus de la recherche en traitement automatique du langage (TALN). La définition du TALN, en soulignant les apports de chaque discipline impliquée avec un éclairage particulier ...

  13. Les forêts tropicales en marge de la certification forestière

    OpenAIRE

    Tsayem Demaze, Moise

    2008-01-01

    La certification forestière a émergé au début des années 1990. Près de 20 ans après, cette activité, entre normalisation de la gestion forestière durable et marketing écologique, affiche une expansion continue en termes de surfaces forestières certifiées par deux des principaux organismes qui dominent le secteur : le Programme for Endorsement of Forest Certification schemes (PEFC) et le Forest Stewardship Council (FSC). Le traitement graphique et cartographique des données statistiques de ces...

  14. MASTURBATION ET THERAPEUTIQUE : L'EXEMPLE DU TRAITEMENT DES AUTEURS D'AGRESSIONS A CARACTERE SEXUEL

    OpenAIRE

    Le Bodic, Cédric

    2009-01-01

    Dans cet article, nous proposons de nous attarder sur le passage de la masturbation pathogène à la masturbation comme technique thérapeutique, dans le cadre particulier de l'agression sexuelle. Dans son cours consacré aux anormaux, Foucault renseigne sur la figure du masturbateur et propose, derrière une archéologie de l'anomalie, de concevoir que l'anormal tel qu'il se construit au XIXe siècle, naît de trois figures : le monstre, l'individu à corriger et le masturbateur ou l'enfant masturbat...

  15. Humaniser la peine? Ethnographie du traitement pénal en maison d'arrêt

    OpenAIRE

    Bouagga, Yasmine

    2013-01-01

    While French jails are facing the double-bind of an increasing number of prisoners to manage efficiently, and pressures to humanize their treatment, the development of judicial procedures and the role of legal professionals in the daily functioning of the prison changes practices of custody. Through the ethnographic survey of two jails (observations and interviews with prisoners, staff, parole judges, lawyers, etc.), the dissertation contributes to a sociology of institutions and of law in ac...

  16. Vision et langage: quelle importance du traitement en parallèle?

    OpenAIRE

    Clarke, Stephanie

    2010-01-01

    The visual system of man and of non-human primates is organised in a way which favours parallel processing. Different aspects of visual information, such as colour, shape or motion are processed independantly. Focal hemispheric lesions can thus cause very selective deficits. The parvo- and magnocellular pathways, specialised in the processing of psychophysically different visual stimuli, have separate representations at the cortical level. Two main pathways are involved in visual recognition ...

  17. Restauration des pistes sonores optiques cinématographiques : approche par traitement d'images

    OpenAIRE

    Hassaïne, Abdelâali

    2009-01-01

    La restauration des films anciens est un domaine de recherche qui a été largement étudié par la communauté scientifique. La restauration de la piste son optique, quant à elle, n'a été en pratique effectuée que dans le domaine audio, bien qu'elle constitue une image continue sur la pellicule photographique, située entre la succession des images et les perforations. Deux types de pistes son optiques existent : les pistes son à largeur variable qui contiennent une région transparente située entr...

  18. TECHNIQUES NUMERIQUES DE TRAITEMENT DU SIGNAL POUR LES FUTURS RESEAUX D’ACCES OPTIQUES

    OpenAIRE

    TRUONG, Tuan-Anh

    2014-01-01

    This thesis aims at improving the spectral efficiency of fiber-based optical transmissions in the context of access networks where an Intensity Modulated/Direct Detected (IMDD) technique is used. In such a context, an increase of fiber length or data rate might lead to significant inter symbol interference problem. For the reason of cost, instead of investing in expensive technologies, a telecom operator might prefer compensating transmission detriments by means of signal processing technique...

  19. Traitement du signal et images LC/MS pour la recherche de biomarqueurs

    OpenAIRE

    Li-Thiao-Té, Sébastien

    2009-01-01

    La spectrométrie de masse LC/MS est une technique de chimie analytique très prometteuse pour la recherche de biomarqueurs protéiques. Cette thèse aborde la correction de certaines distortions : l'alignement des images LC/MS et la normalisation des intensités. Nous étudions ensuite un détecteur de signaux a contrario et calculons la limite de détection.

  20. Assistance par ordinateur de gestes mini-invasifs de traitements de la tumeur de la prostate

    OpenAIRE

    Wu, Ke

    2014-01-01

    The work of this Thesis is focused on image guided focal therapy of prostate cancer by High Intensity Focused Ultrasound (HIFU). Currently MRI is the only imaging technique that can locate the tumor in prostate. In contrast, the tumor is not visible in the ultrasound image which is used to guide the HIFU planning and therapy. The aim of the Thesis is to provide registration techniques of T2 MRI to ultrasound. Two approaches were explored: 1) Region-based registration. More particularly, we st...