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Sample records for apres chirurgie bariatrique

  1. Pronostic visuel et évolution réfractive après chirurgie de la cataracte congénitale avec implantation primaire: étude d'une série de 108 cas

    Science.gov (United States)

    Hafidi, Zouheir; Ibrahimy, Wafaa; Ahid, Samir; Handor, Hanan; Ouafae Cherkaoui, Lalla; Bencherif, Zahid; Laghmari, Mina; Ouazzanni, Btissam; Boutimzine, Noureddine; Daoudi, Rajae

    2013-01-01

    La cataracte congénitale constitue la cause la plus fréquente de cécité évitable chez les enfants. Le but de cette étude est d’évaluer le pronostic réfractif et fonctionnel, des enfants opérés de cataracte congénitale avec implantation. Il s'agit d'une étude rétrospective de 108 enfants, dont 85 cataractes bilatérales, 23 unilatérales opérés entre 2007 et 2011. La réfraction a été mesurée à 1 mois, 3 mois, 6 mois, 1 an, 2 ans, 3 ans et/ou 4 ans en post-opératoire. La meilleure acuité visuelle corrigée, ainsi que l'incidence des complications post-opératoires ont été analysé. L’âge moyen de la chirurgie était de 25 mois avec une durée moyenne de suivi de 3,17 ans. Les complications retrouvées étaient l'inflammation, la prolifération secondaire, et le glaucome. L'acuité visuelle (AV) moyenne corrigée finale était de 5,75/10e pour les formes bilatérales, et de 4,16/10e pour les unilatérales (p = 0,001). Les facteurs de mauvais pronostic retrouvés étaient l’âge tardif de la chirurgie, la densité de la cataracte et la survenue de complications (p = 0,001). L'incidence des complications post-opératoires était significativement plus élevé chez les enfants opérés à un jeune âge (p = 0,001). Les facteurs de mauvais pronostic visuel chez les enfants opérés pour cataracte congénitale avec implantation, sont représentés par le caractère unilatéral de la cataracte, l’âge tardif de la chirurgie, la densité de la cataracte et la survenue de complications post opératoires. PMID:24672622

  2. Chirurgie in die Grieks-Romeinse era

    Directory of Open Access Journals (Sweden)

    François P. Retief

    2006-09-01

    Full Text Available In die Grieks-Romeinse era het mediese behandeling kenmerkend uit drie elemente bestaan, naamlik regimen (dieet en gesonde leefwyse, geneesmiddels en chirurgie – laasgenoemde alleen toegepas indien regimen en geneesmiddels onsuksesvol was. Bewyse van primitiewe chirurgie dateer terug na die Bronstydperk, en in Homerus se eposse is heelwat vermelding van die chirurgiese hantering van oorlogswonde, met tussenkoms van die gode. Met die koms van empiriese geneeskunde in die 5de eeu v.C. het chirurgie in die Hippokratiese Corpus prominent gefigureer met beduidende bydraes in veral die ortopediese veld en hoofbeserings. Uitbouing van anatomiese en fisiologiese kennis, gebaseer op disseksie van menslike kadawers in Alexandrië vanaf die laat 4de eeu v.C., het chirurgie ’n hupstoot gegee. Teen die Romeinse era vanaf die 2de eeu v.C. het snykundetegnieke (en -instrumente beduidend verbeter, maar is steeds oorwegend deur Griekse geneeshere beoefen. Van geneeshere is steeds verwag om al drie bovermelde terapeutiese modaliteite te bemeester, maar chirurgie het meer aansien verwerf en daar is al meer in onderafdelings van chirurgie soos oogheelkunde, vrouesiektes en verloskunde, blaaskwale en mond- en keelsnykunde gespesialiseer. Militêre geneeskunde was in die Romeinse Ryk ’n belangrike aktiwiteit, en het veral traumachirurgie uitgebou. Betreding van die buik- en toraksholtes was nie meer noodwendig fataal nie, en veeartsenykunde het tot stand gekom. Die eerste beduidende chirurgiehandboek ná die Hippokratiese Corpus is in die 1ste eeu n.C. deur Celsus opgestel. Vanaf die 3de eeu het die chirurgieberoep min vordering gemaak, die beroepstaal het mettertyd van Grieks na Latyn verander en kundigheid is later veral deur Islam-geneeshere na die Middeleeue en later oorgedra.

  3. La chirurgie du diaphragme sous aortique

    Science.gov (United States)

    Moutakiallah, Younes; Maaroufi, Ilham; Aithoussa, Mahdi; Bamous, Mehdi; Abdou, Abdessamad; Atmani, Noureddine; Hatim, Abdedaïm; Amahzoune, Brahim; Bekkali, Youssef El; Boulahya, Abdelatif

    2016-01-01

    Le diaphragme sous aortique se caractérise par une certaine latence clinique et une faible morbi-mortalité. La chirurgie reste le traitement de choix malgré un réel risque de récurrence à long terme. Nous rapportons 18 patients opérés entre Avril 1994 et Mars 2011 pour diaphragme sous aortique d’âge moyen de 18,1±9,7 ans avec 11 patients de sexe masculin. Le diaphragme était de nature fibreuse chez 13 patients et fibro-musculaire chez 5 patients. Tous les patients ont été opérés par résection de diaphragme associée à une myectomie, une plastie aortique, une fermeture de communication interventriculaire et une ligature de canal artériel perméable respectivement chez 3, 3, 2 et 2 patients. La Mortalité opératoire était nulle et sans aucun cas de trouble de conduction postopératoire. Le suivi a duré en moyenne 44,3±36,8 mois sans aucun décès tardif. Deux patients ont présenté une récidive de diaphragme qui a nécessité une réopération avec bonne évolution. La tendance actuelle dans la chirurgie du diaphragme se fait vers des interventions précoces et des résections plus extensives. Cependant, le risque de récidive impose une surveillance échographique systématique et rapprochée. PMID:27516830

  4. Stenosen bei Morbus Crohn: Endoskopie vs. Chirurgie

    Directory of Open Access Journals (Sweden)

    Bachleitner-Hofmann T

    2012-01-01

    Full Text Available Etwa 1/3 aller Patienten mit Morbus Crohn entwickelt im Krankheitsverlauf Fibrostenosen mit Symptomen der intestinalen Obstruktion. Gemäß dem Verteilungsmuster der Erkrankung kommen Fibrostenosen im gesamten Intestinaltrakt vor, wenngleich sie am häufigsten im terminalen Ileum, Kolon sowie im Bereich ileokolonischer Anastomosen auftreten. Als Behandlungsoptionen stehen die chirurgische Resektion, chirurgische Strikturplastik-Techniken sowie die endoskopische Ballondilatation zur Verfügung. Bei langen bzw. komplizierten Stenosen (mit Fistel- oder Abszessbildung ist die chirurgische Resektion Therapie der Wahl. Die Resektion sollte so sparsam wie möglich erfolgen, um den Verlust intestinaler Resorptionsfläche zu minimieren. Strikturplastik-Techniken ermöglichen den kompletten Verzicht auf eine Darmresektion, was insbesondere bei Patienten mit multiplen Stenosen von Vorteil ist. Bei kurzen, unkomplizierten und endoskopisch erreichbaren Stenosen ist die endoskopische Ballondilatation eine vielversprechende Alternative zur Chirurgie mit guten Langzeitergebnissen und niedriger Komplikationsrate. Eine adäquate präoperative/ präinterventionelle Diagnostik ist von zentraler Bedeutung, um die jeweiligen Verfahren bestmöglich einsetzen zu können.

  5. Intraoperativer Ultraschall zur Registrierung von Knochenstrukturen in der navigierten Chirurgie

    OpenAIRE

    Brendel, Bernhard

    2005-01-01

    Im Rahmen dieser Arbeit wird untersucht, in wie weit intraoperativer Ultraschall zu einer minimal-invasiven und präzisen Registrierung von Knochenstrukturen in der navigierten Chirurgie geeignet ist. Für die genaue Positionsbestimmung von Knochenstrukturen mit Ultraschall ist die exakte Kalibrierung des Ultraschallwandlers notwendig. Es wird ein Kalibrierverfahren vorgestellt, das einen einfachen Aufbau mit hoher Präzision verbindet. Weiterhin wird ein Registrierungsverfahren b...

  6. [Thoughts on the Revue de Chirurgie Plastique (1931-34) and the Revue de Chirurgie Structive (1935-38)].

    Science.gov (United States)

    Vrebos, J

    2007-08-01

    The history of modern plastic surgery starts when a young, restless ENT man, Dr M. Coelst, started a training in Plastic Surgery with Sebileau in Paris and Joseph in Berlin. This man of vision and far-sighted imagination realized that the separated efforts and publications of so many pioneers, scaterred all over the world, would be lost if not gathered in a scientific journal only devoted to plastic surgery for the benefit of all. This brought him to the idea of establishing, in 1931, at his own initiative, the first international Journal of Plastic Surgery ever published, the Revue de Chirurgie Plastique, fifteen years before the USA Journal Plastic and Reconstructive Surgery and sixteen years before the British Journal of Plastic Surgery. The name of the journal was changed in 1935 to the Revue de Chirurgie Structive. Coelst' Revue was promptly accepted as the leading Journal of Plastic Surgery and all the internationally known plastic Surgeons contributed to it by scientific papers of great value, even today.

  7. U.S. plastic surgeons who contributed to the Revue de Chirurgie Plastique and the Revue de Chirurgie Structive (1931-1938): "Giants" in our specialty.

    Science.gov (United States)

    Rogers, B O

    1999-01-01

    The Revue de Chirurgie Plastique and the Revue de Chirurgie Structive, Brussels (1931-1938), edited by Maurice Coelst, M.D. from Brussels, were the first, full-fledged medical publications specifically devoted to plastic, reconstructive, and aesthetic surgery. Publishing original articles by J.W. Maliniac, J. Eastman Sheehan, and brief summaries of papers read at plastic surgery societies by C.R. Straatsma, L.A. Peer, G. Aufricht, and other well-known American plastic surgeons, these Revues drew attention to surgeons, most of whom were responsible for organizing the American Society of Plastic and Reconstructive Surgeons in 1931, the same year in which the Revue de Chirurgie Plastique first appeared.

  8. British plastic surgeons who contributed to the Revue de Chirurgie Plastique and the Revue de Chirurgie Structive (1931-1938): "the Big Four" in their Speciality.

    Science.gov (United States)

    Rogers, B O

    2001-01-01

    The Revue de Chirurgie Plastique and the Revue de Chirurgie Structive, Brussels (1931-1938), edited by Maurice Coelst, M.D. from Brussels, were the first, full-fledged medical publications devoted specifically to plastic, reconstructive, and aesthetic surgery. Publishing original articles by H.D. Gillies, P.T. Kilner, A.H. McIndoe, and R. Mowlem--the "Big Four" as they were known to both English and American plastic surgeons--the Revues drew attention to these four surgeons who were mainly responsible for developing the prestige of English plastic surgery in the early 1930s.

  9. Scientific contributions of U.S. plastic surgeons to the Revue de Chirurgie Plastique and the Revue de Chirurgie Structive, Brussels (1931-1938).

    Science.gov (United States)

    Vrebos, J

    1999-01-01

    The author emphasizes the close cooperation between U.S. plastic surgeons and the first international journal entirely devoted to plastic surgery, the Revue de Chirurgie Plastique (1931-1934) later to become the Revue de Chirurgie Structive (1935-1938) published under the editorship of Maurice Coelst, M.D. from Brussels. By the accurate recording of original articles, book reviews, proceedings of their annual meetings and summaries in three different languages (English, French, German), the author stresses the intense scientific dynamism and the achievements made by the U.S. pioneers of this new speciality, which really started during World War I.

  10. Surgery of malignant pancreatic tumors; Chirurgie maligner Pankreastumoren

    Energy Technology Data Exchange (ETDEWEB)

    Loos, M.; Friess, H.; Kleeff, J. [Klinikum rechts der Isar, Technische Universitaet Muenchen (Germany). Chirurgische Klinik und Poliklinik

    2009-02-15

    Ductal adenocarcinoma is the most common malignant tumor of the pancreas. Despite great efforts in basic and clinical pancreatic cancer research, the prognosis remains poor with an overall 5-year survival rate of less than 5%. Complete surgical resection represents the only curative treatment option and 5-year survival rates of 20-25% can be achieved following curative resection and adjuvant chemotherapy. Although pancreatic surgery is considered one of the most technically demanding and challenging procedures, there has been constant progress in surgical techniques and advances in perioperative care with a modern interdisciplinary approach including anesthesiology, oncology, radiology and nursing. This has reduced morbidity and especially mortality rates in high-volume centers. Among extended resection procedures multivisceral and venous resections are technically feasible and should be considered if a complete tumor resection can be achieved. Multimodal regimens have shown promising results, however, only adjuvant chemotherapy is supported by solid evidence from randomized controlled trials. (orig.) [German] Das duktale Adenokarzinom ist der haeufigste maligne Pankreastumor. Trotz intensiver Anstrengungen auf dem Gebiet der Pankreasforschung konnte die Gesamtprognose in den vergangenen Jahren nicht entscheidend verbessert werden. Die einzige potenziell kurative Therapie ist die chirurgische Resektion. In Kombination mit einer adjuvanten Chemotherapie liegen die 5-Jahres-Ueberlebensraten aktuell bei 20-25%. Dank kontinuierlicher Weiterentwicklung der chirurgischen Operationstechnik und Verbesserungen der perioperativen Versorgung der Patienten mit einer engen interdisziplinaeren Zusammenarbeit (Chirurgie, Anaesthesie, Onkologie, Radiologie und Pflege) konnten die perioperative Morbiditaets- und Mortalitaetsraten in den vergangenen Jahren deutlich gesenkt werden. Unter den erweiterten Resektionsverfahren sind Venen- oder multiviszerale Resektionen technisch sicher

  11. The scientific contributions of British Plastic Surgeons to the Revue de Chirurgie Plastique and the Revue de Chirurgie Structive, Brussels (1931-1938).

    Science.gov (United States)

    Vrebos, J

    2001-01-01

    In 1931, Maurice Coelst, M.D. from Brussels started the publication of the first international journal of plastic surgery ever published: the Revue de Chirurgie Plastique (1931-1934), which eventually became the Revue de Chirurgie Structive (1935-1938). In 1936, he established the first European Society of Structive Surgery, which held its first congress in Brussels. Further congresses were held in London in 1937 and in Milan in 1938. It is the collaboration and the participation of British plastic surgeons in this Society, this journal, and these meetings that I want to stress, because I am firmly convinced that these documents fill a gap in the history of Plastic Surgery in Great Britain, since--as far as I know--no detailed information concerning this period was ever published in Plastic Surgery literature.

  12. Respirators: APR Issuer Self Study 33461

    Energy Technology Data Exchange (ETDEWEB)

    Chochoms, Michael [Los Alamos National Laboratory

    2016-07-13

    Respirators: APR Issuer Self-Study (course 33461) is designed to introduce and familiarize employees selected as air-purifying respirator (APR) issuers at Los Alamos National Laboratory (LANL) with the responsibilities, limitations, procedures, and resources for issuing APRs at LANL. The goal is to enable these issuers to consistently provide proper, functioning APRs to authorized users

  13. Respirators: APR Issuer Self Study 33461

    Energy Technology Data Exchange (ETDEWEB)

    Chochoms, Michael [Los Alamos National Laboratory

    2016-03-01

    Respirators: APR Issuer Self-Study (course 33461) is designed to introduce and familiarize employees selected as air-purifying respirator (APR) issuers at Los Alamos National Laboratory (LANL) with the responsibilities, limitations, procedures, and resources for issuing APRs at LANL. The goal is to enable these issuers to consistently provide proper, functioning APRs to authorized users

  14. Eine neuartige Roboterkinematik für die laparoskopische Single-Port Chirurgie

    OpenAIRE

    Sanagoo, Arash

    2015-01-01

    Minimal invasive Operationstechniken haben sich in den letzten Jahren sehr schnell weiterentwickelt. Unter anderem konnte sich die roboterassistierte Laparoskopie auf dem Markt etablieren. Solche Systeme können jedoch sehr eingeschränkt für die Single-Port Laparoskopie eingesetzt werden. Im Rahmen dieser Arbeit wurde basierend auf einer sphärischen Parallelkinematik ein kompakter Manipulator entwickelt. Dieser Manipulator wird in erster Linie für die laparoskopische Single-Port Chirurgie g...

  15. Diagnostic Strategy in APR1400

    International Nuclear Information System (INIS)

    These features may bring out changes in operator tasks, changing the characteristics of tasks, or creating new tasks. Diagnostic strategy for identifying anomaly may be different especially in APR1400 from that in the analog control room due to the change of human-system interface, i.e. alarm system and display system. Since the first plant of APR1400 is being built at this moment, it is not known what strategies the operators will adopt in diagnosis tasks in the new operating environment. In this light, this paper aims at investigating operator's diagnostic strategies which are appropriate for APR1400. In order to collect data, several different approaches which are complementary are used to identify diagnostic strategies in the digital control room: analysis on audio/video recording of operation, observation in the simulator, and interview with the operators. The result shows that the digital control room introduces new strategies in the diagnosis, compared with the analog control room, and also changed the characteristics of strategies, mostly, by getting more support from the computerized system. This paper investigated how the digitalized control room may influence operator's diagnostic strategies. Several different approaches, i. e., audio/video record, observation of training, and the interview with operators, were used to gather information about the operator's behaviors. As a conclusion, this paper figured out that the digital control room introduces new strategies in the diagnosis, compared with the analog control room, and also changed the characteristics of the strategies, mostly, by getting more support from the computerized system. The operators interviewed also commented that the diagnosis in the APR1400 is quicker, more correct, and easier, compared with the analog control room

  16. Chirurgie filtrante du glaucome: sécurité et efficacité

    OpenAIRE

    Varga, Zsolt

    2015-01-01

    Le Glaucome est l’une des causes principales de cécité dans le monde. Le nombre de personnes atteintes devrait presque doubler d’ici 25 ans en raison du vieillissement de la population. La chirurgie du glaucome est effectuée pour réduire la pression intraoculaire et arrêter ou ralentir la progression du glaucome avancé non-contrôlé, afin d’éviter la perte de vision et préserver la qualité de vie. De nouvelles interventions chirurgicales ont été développées avec pour objectif de réduire le tau...

  17. Pharmacologie de la morphine chez les sujets obèses avant et après chirurgie de l'obésité

    OpenAIRE

    Lloret Linares, Célia,

    2013-01-01

    In this thesis, we show that obesity is a factor of pharmacodynamic and pharmacokinetic morphine variability. In particular, absorption and exposure to oral morphine increases significantly after gastric bypass surgery . We demonstrate the role of enterocyte content of efflux transporter P-gp in determining the absorption and exposure to morphine.; Au cours de cette thèse, nous montrons que l’obésité est un facteur de variabilité pharmacodynamique et pharmacocinétique de la morphine. En parti...

  18. Les masques de la masculinité dans le recours à la chirurgie esthétique

    Directory of Open Access Journals (Sweden)

    Michael Atkinson

    2009-10-01

    Full Text Available Depuis la fin des années 1990, un nombre croissant de Canadiens ont recours à la chirurgie esthétique comme véritable projet corporel. Un problème sociologique central émerge de ce recours massif. Pourquoi une pratique traditionnellement féminine devient-elle une pratique hautement signifiante pour ces Canadiens? La chirurgie plastique comme pratique culturelle équivaut à une mesure physique de l’évolution des pouvoirs entre les genres dans des pays comme le Canada. En outre, elle sert d’indicateur corporel de la manière dont les hommes vivent la crise actuelle de la masculinité. A la suite de Douglas (1970 ou Sontag (1991, le bouleversement normatif des corps, leurs modifications et leurs représentations publiques sont, en effet, des mesures corporelles des changements des relations de pouvoir entre hommes et femmes. Ces évolutions au Canada déstabilisent réellement les modèles de masculinité hégémonique, et sont directement observables à travers les modifications à même la peau de ces hommes. Ces recours chirurgicaux permettent de révéler les doutes, l’anxiété et l’anomie qui parsèment les cultures contemporaines. Ils redéfinissent les formes de ce travail corporel traditionnellement féminin. Il s’agit donc d’analyser comment les corps masculins modifiés par la chirurgie constituent une mesure aiguë du genre et un révélateur d’identités dans les sociétés comme le Canada.

  19. Containment performance analysis for EU APR1400

    International Nuclear Information System (INIS)

    During a severe accident, as the last barrier of DID (Defense In Depth) strategy, the containment has an important role to limit the release of the radioactive material to environment. The containment should be able to maintain its structural integrity to prevent the release of the radioactive materials contained in it. In this paper, the behavior of pressure and temperature in the containment is evaluated for various accident conditions. EU APR1400 (European APR1400) is equipped with RDS (Rapid Depressurization System), HMS (Hydrogen Mitigation System), SACSS (Severe Accident Containment Spray System), and PECS (Passive Ex vessel Cooling System) to mitigate the severe accident consequences and eventually to keep the containment integrity. Depending on the availabilities of these mitigation systems, the containment undergoes different transients in pressure and temperature

  20. Apreçamento de derivativos bidimensionais

    Directory of Open Access Journals (Sweden)

    Hugo Daniel de Oliveira Azevedo

    2005-09-01

    Full Text Available Neste artigo analisamos o apreçamento de contratos que tenham seus resultados atrelados a mais de um ativo subjacente, em especial, opções bidimensionais. Para isto usamos a fórmula desenvolvida por Margrabe (1978 e o modelo de árvores de Rubinstein (1991a. Em seguida apresentamos exemplos práticos de opções bidimensionais e apreçamos estas opções. Além disto, sugerimos a incorporação de outros instrumentos, negociados no exterior, ao mercado de derivativos brasileiro.In this article we analyze the pricing of contracts that have their payoffs linked to more than one underlying asset, in special, bidimensional options. To achieve this purpose we use the formula developed by Margrabe (1978 and the tree model of Rubinstein (1991a. Next, we present practical examples of bidimensional options and price these options. Moreover we suggest the incorporation of two other instruments, negotiated abroad, to the Brazilian derivative markets

  1. Design Characteristics of the APR+ Containment Spray System

    International Nuclear Information System (INIS)

    We, KEPCO E and C, are implementing APR+ design development phase II project, which is owned by the KHNP. The APR+ Containment Spray (CS) System is developed as a four (4) 100%-capacity train system which shares the pumps, heat exchangers, valves, and piping with the Shutdown Cooling (SC) System, meeting the N+2 design concept (capable of satisfying the safety function with a single failure and a concurrent component unavailability due to maintenance) and still maintaining the number and capacity of the system components similar to the APR1400 CS System and SC System combined. The design concept and system configuration of the APR+ CS System are presented

  2. Design Characteristics of the APR+ Containment Spray System

    Energy Technology Data Exchange (ETDEWEB)

    Doh, Gyu Bong; Park, Jong Ha; Chang, Jae Wang [KEPCO Engineering and Construction Co., Yongin (Korea, Republic of)

    2012-05-15

    We, KEPCO E and C, are implementing APR+ design development phase II project, which is owned by the KHNP. The APR+ Containment Spray (CS) System is developed as a four (4) 100%-capacity train system which shares the pumps, heat exchangers, valves, and piping with the Shutdown Cooling (SC) System, meeting the N+2 design concept (capable of satisfying the safety function with a single failure and a concurrent component unavailability due to maintenance) and still maintaining the number and capacity of the system components similar to the APR1400 CS System and SC System combined. The design concept and system configuration of the APR+ CS System are presented

  3. Vingt ans après…

    Directory of Open Access Journals (Sweden)

    François Burgat

    2002-05-01

    Full Text Available Le dixième numéro des Chroniques Yéménites, publié vingt ans après la création du Centre Français d'Archéologie et de Sciences Sociales de Sanaa reflète des ambitions souvent exprimées: donner une chance aux jeunes chercheurs et couvrir un large éventail disciplinaire au service de l'affirmation de la vocation régionale du Centre. Depuis Sanaa ou Paris, chercheurs, doctorants ou stagiaires, de l'Ecole normale supérieure, de l'INALCO, de l'Université de Sanaa et de bon nombre d'institu...

  4. Untersuchung des Reinigungseffektes von Ultraschall auf Oberflächen von Chirurgie-Instrumenten und dessen prototypische Umsetzung in ein Dekontaminationsverfahren

    OpenAIRE

    Kahlen, Insa

    2012-01-01

    Viele Medizinprodukte aus der Chirurgie stellen besonders hohe Anforderungen an ihre Aufbereitung, da sie z.B. wie die so genannten „Langschaftinstrumente“ enge und sehr langgestreckte Lumen aufweisen, die zum Teil nicht einsehbar sind. Laut der Richtlinie „Anforderungen an die Hygiene bei der Aufbereitung von Medizinprodukten“ vom RKI und der BfArM soll die Aufbereitung von solchen Medizinprodukten durch Anwendung validierter Verfahren durchgeführt werden und der Erfolg stets nachvollziehbar...

  5. Involvement of Stringent Factor RelA in Expression of the Alkaline Protease Gene aprE in Bacillus subtilis

    OpenAIRE

    Hata, Michihiro; Ogura, Mitsuo; Tanaka, Teruo

    2001-01-01

    Expression of Bacillus subtilis aprE, encoding an extracellular alkaline protease, is positively regulated by phosphorylated DegU, the regulator of a two-component regulatory system, DegS-DegU. We found that the expression of an aprE′-′lacZ fusion was greatly reduced in a disruption mutant with a mutation of relA, which encodes the stringent factor RelA. The level of DegU in the relA mutant was similar to that in the wild-type cell. A relA degU double mutation did not result in a further decr...

  6. 15 CFR 781.3 - Scope of the APR.

    Science.gov (United States)

    2010-01-01

    ... Government locations (see definition in § 781.1 of the APR): (i) Department of Energy locations; (ii) Department of Defense locations; (iii) Central Intelligence Agency locations; and (iv) Department of...

  7. Development of Reference Source Terms for EU-APR1400

    International Nuclear Information System (INIS)

    These source terms are developed for the typical U. S. NPP and do not reflect the design characteristics of EU-APR1400 (1,400 MWe PWR) which will be applied for the EUR certification in European countries. The process of developing the RST for EU-APR1400 is to undergo a similar process that NUREG-1465 had gone through when it came out with its proposed source terms. The purpose of this study is to develop the EU-APR1400 design-specific RST complied with the EUR. The Large LOCA is the reference equence used in the NUREG-1465 evaluation, whereas the EUAPR1400 risk-significant sequences are dominated by small LOCA and non-LOCA sequences. Moreover, when considering the EU-APR1400 has many design features to mitigate the consequences of severe accident phenomena, it is not surprising that the aspects of both release fractions and durations are distinctly different from NUREG-1465. This RST will be continuously updated to reflect to the design features of EU-APR1400, and then, be used as the reference for design purposes such as criteria satisfaction of radioactivity releases, equipment survivability, control room habitability for severe accident, and so on

  8. Determination of PARs capacity for HMS in EU APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, Do Hyun [KHNP CRI, Daejeon (Korea, Republic of)

    2012-10-15

    The Hydrogen Mitigation System (HMS) is designed to control combustible gas, mainly hydrogen gas (H2) inside containment within the acceptable limits by the Passive Autocatalytic Recombiner (PAR) with consideration of hydrogen generation during severe accidents. In EU APR1400 (European APR1400), a passive hydrogen control system which is composed of a number of PARs, is adopted for the mitigation of the hydrogen induced risks. For the design of the HMS, the expected ranges for the global and local hydrogen concentrations in the containment and the increase rate of the concentrations should be examined to specify the required capacity and locations of the PARs. This paper describes the determination of PARs capacity for HMS in EU APR1400.

  9. Concurrent administration of adjuvant chemotherapy and radiotherapy after breast-conservative surgery enhances late toxicities; La chimiotherapie concomitante de la radiotherapie augmente la toxicite tardive apres chirurgie conservatrice du cancer du sein

    Energy Technology Data Exchange (ETDEWEB)

    Toledano, A. [Hopital Tenon, Service d' oncologie-radiotherapie 75 - Paris (France); Garaud, P.; Body, G.; Le Floch, O.; Calais, G. [Centre Hospitalier Universitaire Bretonneau, 37 - Tours (France); Serin, D. [Institut Sainte-Catherine, 84 - Avignon (France); Fourquet, A. [Institut Curie, 75 - Paris (France); Bosset, J.F.; Miny-Buffet, J. [Centre Hospitalier Universitaire Minjoz, 25 - Besancon (France); Favre, A. [Centre Hospitalier Universitaire La Source, 45 - Orleans (France); Azria, D. [Centre de Lutte Contre le Cancer Val d' Aurelle, 34 Montpellier (France)

    2006-06-15

    In 1996, a multicenter randomized study comparing after breast-conservative surgery. sequential vs concurrent adjuvant chemotherapy (CT) with radiation therapy (RT) was initiated (ARCOSEIN study). Seven hundred sixteen patients were included in this trial. After a median follow-up of 6.7 (4.3 -9) years, we decided to prospectively evaluate the late effects of these two strategies. Patients and methods - A total of 297 patients were asked to follow-up from the five larger including institutions. Seventy-two percent (214 patients) were eligible for late toxicity. After breast-conserving surgery with axillary dissection, patients were treated either with sequential treatment with CT first followed by RT (arm A) or CT administered concurrently with RT (arm B). In all patients, CT regimen combined mitoxantrone (12 mg/m{sup 2}). 5-FU (500 mg/m{sup 2}), and cyclophosphamide (500 mg/m{sup 2}), 6 cycles (day 1-day 21). In arm B, patients received concurrently the first 3 cycles of CT with RT. In arm A, RT started 3 to 5 weeks after the 6. cycle of CT. Conventional RT was delivered to the whole breast using a 2 Gy-fraction protocol to a total dose of 50 Gy ({+-} boost to the primary tumour bed). The assessment of toxicity was blinded to treatment and was graded by the radiation oncologist according to the LENT-SOMA scale. Skin pigmentation was also evaluated using a personal 5-points scoring system (excellent, good, moderate, poor, very poor). Results - Among the 214 evaluated patients, 107 were treated in each arm. The two populations were homogeneous for patients', tumors' and treatment characteristics. Subcutaneous fibrosis (SF), telangiectasia (T), skin pigmentation (SP), and breast atrophy (BA) were significantly increased in arm B. Twenty patients experienced grade superior or equal to 2 (SF) in arm B vs five in arm A (P 0.003). Twenty-five and seven patients showed grade superior or equal to 2 (T) in ann B and A, respectively (P = 0.001). Forty-four and twenty patients showed grade superior or equal to 2 (BA) in arm B and A, respectively (P 0.0006). Thirty patients experienced grade superior or equal to 3 (SP) in arm B vs fifteen in arm A (P= 0.02). No statistical difference was observed between the two arms concerning grade superior or equal to 2 pain, breast oedema and lymphedema. No deaths were caused by late toxicity. Conclusion - Following breast conserving surgery, the concurrent use of CT with RT is significantly associated with an increase incidence of grade 2 or greater late side effects. (author)

  10. Oesophageal squamous cell carcinoma Stade 3. State of surgery after radio chemotherapy (R.C.T.); Carcinomes malpighiens de l'oesophage de stade 3, place de la chirurgie apres chimioradiotherapie

    Energy Technology Data Exchange (ETDEWEB)

    Triboulet, J.P.; Mariette, C. [Hopital Claude-Huriez, Service de Chirurgie Digestive et Generale, 59 - Lille (France)

    2006-11-15

    Neo-adjuvant chemoradiotherapy is the gold standard of the treatment of advanced oesophageal squamous cell carcinoma. The role of surgery L. chemoradiotherapy is still debated. Feasibility of curative resection depends on dose of radiotherapy, morbi-mortality rates, and nutrition status at the end of the protocol especially for non-responders patients. Adding surgery to radio-chemotherapy improves local tumour control but does not increase overall survival of patients with advanced oesophageal squamous cell carcinoma. According to the two randomized trials published on the subject, surgery is not recommended after chemoradiotherapy for responders. Recommendations of French National Thesaurus are: exclusive chemoradiotherapy as reference, oesophagectomy for residual tumour as alternative for operable patients. Surgery may be proposed for selected non-responders patients and some complete pathology response in expert center. (author)

  11. System Response Analysis of LOCV for APR1400 Using KNAP

    International Nuclear Information System (INIS)

    Korea Electric Power Research Institute (KEPRI) of Korea Electric Power Corporation (KEPCO) has been developed the non-loss-of-coolant accident (non-LOCA) analysis methodology, called as the Korea Non-LOCA Analysis Package (KNAP), for the typical Optimized Power Reactor 1000 (OPR1000) plants. Considering current licensing methodology conducted by ABB-CE, however, the KNAP could be applied to Advanced Power Reactor 1400 (APR1400). In spite of some difference in components of two plant types, there is a close resemblance between their nuclear steam supply systems (NSSS). So, in this study, the loss of condenser vacuum (LOCV) event were analyzed using KNAP for APR1400 to estimate the feasibility of the application and the results were compared with those given in APR1400 Standard Safety Analysis Report (SSAR), which were calculated using the CESEC-III code of ABB-CE. Through the study, it was concluded that the KNAP could be applicable to APR1400 on the view point of LOCV event

  12. Preliminary Results Of LOCA Problem For APR1400 Reactor

    International Nuclear Information System (INIS)

    Several features of NPP with APR1400 nuclear reactor during a loss of coolant accident (LOCA) are investigated in this study. The report describes some main design characteristics of an engineering safety systems of APR1400 and the thermal hydraulic calculation results for steady-state using MARS and RELAP/SCDAPSIM codes. Large Break LOCA accident has been analyzed and evaluated based on acceptable criteria for ECCS given by US NRC. The results from cold leg break LOCA with broken area of 0.0465 m2 in case of high pressure safety injection system (HPSI) failed to operate or 2 and 4 HPSI pumps are activated. The preliminary results of this work is a part of collaboration between INST researchers and KAERI experts in using RELAP tool for safety analysis of NPPs. (author)

  13. Design features of Advanced Power Reactor (APR) 1400 steam generator

    International Nuclear Information System (INIS)

    Advanced Power Reactor 1400 (APR 1400) which is to achieve the improvement of the safety and economical efficiency has been developed by Korea Hydro and Nuclear Power Co., Ltd. (KHNP) with the support from industries and research institutes. The steam generator for APR 1400 is an evolutionary type from System 80+, which is the recirculating U-tube heat exchanger with integral economizer. Compared to the System 80+ steam generator, it is focused on the improved design features, operating and design conditions of APR 1400 steam generator. Especially, from the operation experience of Korean Standard Nuclear Power Plant (KSNP) steam generator, the lessons-learned measures are incorporated to prevent the tube wear caused by flow-induced vibration (FIV). The concepts for the preventive design features against FIV are categorized to two fields; flow distribution and dynamic response characteristics. From the standpoint of flow distribution characteristics, the egg-crate flow distribution plate (EFDP) is installed to prevent the local excessive flow loaded on the most susceptible tube to wear. The parametric study is performed to select the optimum design with the efficient mitigation of local excessive flow. ATHOS3 Mod-01 is used and partly modified to analyze the flow field of the APR 1400 steam generator. In addition, the upper tube bundle support is designed to eliminate the presence of tube with a low natural frequency. Based on the improved upper tube bundle support, the modal analysis is performed and compared with that of System 80+. Using the results of flow distribution and modal analysis, the two mechanisms of flow-induced vibration are investigated; fluid-elastic instability (FEI) and random turbulence excitation (RTE). (authors)

  14. Regulatory Approach for Oversight of APR1400 Constructions

    International Nuclear Information System (INIS)

    This presentation treats of the regulatory approach for the oversight of the APR 1400. It first introduces the licensing system in Korea and after that it describes the inspection program during the construction and commissioning, operation and finally decommissioning phase. Special emphasis is put on the installation inspection (52 items), cold functional inspections (77 items), hydrostatic and hot functional test inspection (23 items) and initial fuel loading and startup test inspections (33 items)

  15. LASER-CHIRURGIE

    OpenAIRE

    КУБЛАНОВА А.А.; САПАРГАЛИЕВА С.А.; ДЕНИСОВА О.С.

    2015-01-01

    Das Wort „Laser“ steht für „Light Amplification by Stimulated Emission of Radiation“. Laserstrahlen sind starke Lichtstrahlen, die durch elektrische Stimulation eines bestimmtes Stoffs (fest, flüssig oder gasförmig) erzeugt werden.Laser werden nach dem Stoff benannt, mit dem sie den Strahl erzeugen. Weitverbreitete Laser sind u. a. Kohlendioxidlaser und Argonlaser.Die Kombination aus der Stärke eines Lichtstrahls und der Fähigkeit, diesen auf eine kleine Fläche zu konzentrieren, verhilft Lase...

  16. Conception et réalisation d'une instrumentation terminale intégrée en chirurgie mini-invasive robotisée

    OpenAIRE

    Van Meer, Frédérick

    2005-01-01

    On assiste depuis quelques années à l'émergence d'une robotique médicale proposée pour accroître la précision des actes, améliorer les conditions de travail de l'équipe chirurgicale et le confort du patient. Nos recherches s'inscrivent dans le projet national EndoXiroB du RNTS dont l'objectif est la réalisation d'un ensemble robotisé de chirurgie mini-invasive. Elles sont dédiées à la conception et à la réalisation, en s'appuyant sur les technologies microsystèmes, d' une instrumentation chir...

  17. Pseudomonas syringae evades host Immunity by degrading flagellin monomers with alkaline protease AprA

    OpenAIRE

    Pel, M.J.C.; Van Dijken, A.J.H.; Bardoel, B.W.; Seidl, M. F.; Van der Ent, S.; van Strijp, J. A. G.

    2014-01-01

    Bacterial flagellin molecules are strong inducers of innate immune responses in both mammals and plants. The opportunistic pathogen Pseudomonas aeruginosa secretes an alkaline protease called AprA that degrades flagellin monomers. Here, we show that AprA is widespread among a wide variety of bacterial species. In addition, we investigated the role of AprA in virulence of the bacterial plant athogen P. syringae pv. tomato DC3000. The AprA-deficient DC3000 ΔaprA knockout mutant was significantl...

  18. Review of APR+ Level 2 PSA. Revision 2

    Energy Technology Data Exchange (ETDEWEB)

    Lehner, John R. [Brookhaven National Lab. (BNL), Upton, NY (United States); Mubayi, Vinod [Brookhaven National Lab. (BNL), Upton, NY (United States); Pratt, W. Trevor [Brookhaven National Lab. (BNL), Upton, NY (United States); Kim, Do Sam [Korea Institute of Nuclear Safety (KINS), Daejeon (Korea, Republic of); Cho, Yong Jin [Korea Institute of Nuclear Safety (KINS), Daejeon (Korea, Republic of); Cho, Sang Jin [Korea Institute of Nuclear Safety (KINS), Daejeon (Korea, Republic of); Kim, In Goo [Korea Institute of Nuclear Safety (KINS), Daejeon (Korea, Republic of)

    2012-02-17

    Brookhaven National Laboratory (BNL) assisted the Korea Institute of Nuclear Safety (KINS) in reviewing the Level 2 Probabilistic Safety Assessment (PSA) of the APR+ Advanced Pressurized Water Reactor (PWR) prepared by the Korea Hydro & Nuclear Power Co., Ltd (KHNP) and KEPCO Engineering & Construction Co., Inc. (KEPCO-E&C). The work described in this report involves a review of the APR+ Level 2 PSA submittal [Ref. 1]. The PSA and, therefore, the review is limited to consideration of accidents initiated by internal events. As part of the review process, the review team also developed three sets of Requests for Additional Information (RAIs). These RAIs were provided to KHNP and KEPCO-E&C for their evaluation and response. This final detailed report documents the review findings for each technical element of the PSA and includes consideration of all of the RAIs made by the reviewers as well as the associated responses. This final report was preceded by an interim report [Ref. 2] that focused on identifying important issues regarding the PSA. In addition, a final meeting on the project was held at BNL on November 21-22, 2011, where BNL and KINS reviewers discussed their preliminary review findings with KHNP and KEPCO-E&C staffs. Additional information obtained during this final meeting was also used to inform the review findings of this final report. The review focused not only on the robustness of the APR+ design to withstand severe accidents, but also on the capability and acceptability of the Level 2 PSA in terms of level of detail and completeness. The Korean nuclear regulatory authorities will decide whether the PSA is acceptable and the BNL review team is providing its comments for KINS consideration. Section 2.0 provides the basis for the BNL review. Section 3.0 presents the review of each technical element of the PSA. Conclusions and a summary are presented in Section 4.0. Section 5.0 contains the references.

  19. Severe Accident Management Strategy for EU-APR1400

    International Nuclear Information System (INIS)

    In EU-APR1400, the dedicated instrumentation and mitigation features for SAM are being developed to keep the integrity of containment and to prevent the uncontrolled release of fission products. In this paper, SAM strategy for EU-APR1400 was introduced in stages. It is still under development and finally the Severe Accident Management Guidance will be completed based on this SAM Strategy. Severe accidents in a nuclear power plant are defined as certain unlikely event sequences involving significant core damage with the potential to lead to significant releases according to EUR 2.1.4.4. Even though the probability of severe accidents is extremely low, the radiation release may cause serious effect on people as well as environment. Severe Accident Management (SAM) encompasses those actions which could be considered in recovering from a severe accident and preventing or mitigating the release of fission products to the environment. Whether those actions are successful or not, depending on a progression status of a severe accident to mitigate the consequences of severe accident phenomena to limit the release of radioactive materials keeping the leak tightness of the Primary Containment, and finally to restore transient severe accident progression into a controlled and safe states

  20. Pseudomonas syringae evades host immunity by degrading flagellin monomers with alkaline protease AprA.

    Science.gov (United States)

    Pel, Michiel J C; van Dijken, Anja J H; Bardoel, Bart W; Seidl, Michael F; van der Ent, Sjoerd; van Strijp, Jos A G; Pieterse, Corné M J

    2014-07-01

    Bacterial flagellin molecules are strong inducers of innate immune responses in both mammals and plants. The opportunistic pathogen Pseudomonas aeruginosa secretes an alkaline protease called AprA that degrades flagellin monomers. Here, we show that AprA is widespread among a wide variety of bacterial species. In addition, we investigated the role of AprA in virulence of the bacterial plant pathogen P. syringae pv. tomato DC3000. The AprA-deficient DC3000 ΔaprA knockout mutant was significantly less virulent on both tomato and Arabidopsis thaliana. Moreover, infiltration of A. thaliana Col-0 leaves with DC3000 ΔaprA evoked a significantly higher level of expression of the defense-related genes FRK1 and PR-1 than did wild-type DC3000. In the flagellin receptor mutant fls2, pathogen virulence and defense-related gene activation did not differ between DC3000 and DC3000 ΔaprA. Together, these results suggest that AprA of DC3000 is important for evasion of recognition by the FLS2 receptor, allowing wild-type DC3000 to be more virulent on its host plant than AprA-deficient DC3000 ΔaprA. To provide further evidence for the role of DC3000 AprA in host immune evasion, we overexpressed the AprA inhibitory peptide AprI of DC3000 in A. thaliana to counteract the immune evasive capacity of DC3000 AprA. Ectopic expression of aprI in A. thaliana resulted in an enhanced level of resistance against wild-type DC3000, while the already elevated level of resistance against DC3000 ΔaprA remained unchanged. Together, these results indicate that evasion of host immunity by the alkaline protease AprA is important for full virulence of strain DC3000 and likely acts by preventing flagellin monomers from being recognized by its cognate immune receptor. PMID:24654978

  1. Pseudomonas syringae evades host immunity by degrading flagellin monomers with alkaline protease AprA

    NARCIS (Netherlands)

    Pel, Michiel J C; van Dijken, Anja J H; Bardoel, Bart W; Seidl, Michael F; van der Ent, Sjoerd; van Strijp, Jos A G; Pieterse, Corné M J

    2014-01-01

    Bacterial flagellin molecules are strong inducers of innate immune responses in both mammals and plants. The opportunistic pathogen Pseudomonas aeruginosa secretes an alkaline protease called AprA that degrades flagellin monomers. Here, we show that AprA is widespread among a wide variety of bacteri

  2. Pseudomonas syringae evades host Immunity by degrading flagellin monomers with alkaline protease AprA

    NARCIS (Netherlands)

    Pel, M.J.C.; Van Dijken, A.J.H.; Bardoel, B.W.; Seidl, M.F; Van der Ent, S.; Van Strijp, J.A.G.

    2014-01-01

    Bacterial flagellin molecules are strong inducers of innate immune responses in both mammals and plants. The opportunistic pathogen Pseudomonas aeruginosa secretes an alkaline protease called AprA that degrades flagellin monomers. Here, we show that AprA is widespread among a wide variety of bacteri

  3. Thermal-hydraulic Analysis of SGTR for Supporting PSA in APR+

    International Nuclear Information System (INIS)

    The Advanced Power Reactor Plus (APR+) is being developed in Korea. To enhance the safety of the APR+, a passive auxiliary feedwater system (PAFS) has been adopted in the APR+. The PAFS completely replaces the conventional active auxiliary feedwater system (AFWS). It is operated by a natural driving force mechanism when demanding auxiliary feedwater. It could maintain the system function of cooling the primary side and remove the decay heat while operated PAFS. For estimating the safety of APR+ design, the probabilistic safety assessment (PSA) of APR+ is performed. As the PAFS replaces the conventional AFWS, it is required to verify the cooling capacity of PAFS for the accurate evaluation. For this reason, this paper discusses the cooling performance of the PAFS while transient accidents

  4. An ATWS Analysis for EU-APR1400 Following the European Utility Requirement

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Minshin; Lee, Cheolshin; Sohn, Jongjoo [KEPCO Engineering and Construction Company., Inc., Daejeon (Korea, Republic of)

    2013-05-15

    This paper presents the results of the evaluation of the ATWS events with respect to Reactor Coolant System (RCS) overpressure and re-criticality for the European APR1400 (EU-APR1400) according to European Utility Requirement (EUR). This paper evaluates the ATWS impact on the EU-APR1400 by applying EUR. Based on the results of safety analysis for ATWS events, all the acceptance criteria for EUR can be satisfied due to the proper functioning of ATWS mitigation systems. However the four events are investigated only in this paper, and hence the results of this paper can not be concluded that the EU-APR1400 design satisfy all requirements for the EUR. Therefore, a further study for all Design Basis Event Category 2 (DBC2) events with ATWS needs to be performed in order to assess the comprehensive impact of ATWS events for the EU-APR1400 design.

  5. Implementation of Low Boron Core for APR1400 Initial Cycle

    International Nuclear Information System (INIS)

    Low boron capability of a nuclear power plant is rather a qualitative specification requiring the nuclear power plant to be shut down by control rods alone at any time of a plant cycle according to EUR. The reduction of soluble boron is beneficial since it gives the reduction of the corrosive effects in the plant system and improves plant safety giving more negative MTC. Thus, it is necessary to reduce the amount of soluble boron for the criticality to achieve the low boron capability. However, the reduction of soluble boron has its own set of specific challenges that must be overcome. There are two methods to enable the reduction of soluble boron without modifying plant system significantly. The goal of this study is to investigate the loading pattern to achieve the soluble boron reduction for Shin-Kori Unit 5 APR1400 initial core using the low and high content gadolinia burnable absorbers with standard fuel rod enrichment and to verify the feasibility of low boron core with conventional gadolinia burnable absorbers only. For this study, KARMA has been employed to solve 2-D Transport equation, and ASTRA is used for full core analysis. It was possible to achieve the low boron core for APR1400 Cycle 1 using extended usage of two types of gadolinia burnable absorbers sacrificing fuel cycle economy a little bit while enhancing plant safety significantly. Gd rod patterns within an assembly were optimized through geometrical weighting and loading pattern was developed based on these patterns. The amount of soluble boron reduction achieved is 45.4%. The improvement in plant safety is significant resulting in the reduction of least negative best-estimate MTC by about 4 pcm. Also shutdown margin is increased slightly for low boron core. However, the behavior of axial power shape turns out to be undesirable showing a relatively large fluctuation caused by the more negative MTC. It was found that the low boron core might impose kind of operational difficulty. It is usually

  6. Development of Core Simulator (CoSi) for APR1400 And Analysis of LPPT Result using APR1400-CoSi

    Energy Technology Data Exchange (ETDEWEB)

    Moon, Sang-Rae; Kim, Yong-Bae; Lee, Eun-Ki [KHNP-CRI, Daejeon (Korea, Republic of)

    2014-10-15

    According to NRC guidelines, Low Power Physics Test (LPPT) is required to be performed in low temperature/low pressure (160 .deg. C/42.2 kg/cm{sup 2}) as well as NOT/NOP (291.3 .deg. C/158.2 kg/cm{sup 2}) because Shin-Kori Unit 3 is FOAK nuclear power plant. Low Power Physics Test (LPPT) is essential to verify the nuclear design and robustness of reactor safety. LPPT consists of initial criticality, Point of Adding Heat (POAH), All Rod Out (ARO) Boron Concentration, Isothermal Temperature Coefficient (ITC), Control Rod Worth measurements and so on. KHNP-CRI has developed the Core Simulator for APR1400 (APR1400-CoSi) in order to improve the ability performing the LPPT. Especially, APR1400-CoSi has enhanced capability to calculate the full Core neutronic parameters by revising RAST-K that is three dimensional real time core kinetic program. APR1400-CoSi has been developed for education-training of Low Power Physics Test(LPPT). Particularly, APR1400-CoSi has an enhanced capability to calculate the full core neutronic parameters by revising RAST-K which is a three dimensional real time core kinetics program. Low Power Physics Test (LPPT) was performed using APR1400-CoSi and the results showed very similar values with the predicted ones. In other words, the initial core model of Shin-Kori Unit 3 in APR1400-CoSi system has been verified to be appropriate enough. Also, it was confirmed that the test range of Low Power Physics Test (LPPT) reamains effective even though the largest incremental bank reactivity is inserted in core by analyzing the power change during the rod SWAP test.

  7. Development of Core Simulator (CoSi) for APR1400 And Analysis of LPPT Result using APR1400-CoSi

    International Nuclear Information System (INIS)

    According to NRC guidelines, Low Power Physics Test (LPPT) is required to be performed in low temperature/low pressure (160 .deg. C/42.2 kg/cm2) as well as NOT/NOP (291.3 .deg. C/158.2 kg/cm2) because Shin-Kori Unit 3 is FOAK nuclear power plant. Low Power Physics Test (LPPT) is essential to verify the nuclear design and robustness of reactor safety. LPPT consists of initial criticality, Point of Adding Heat (POAH), All Rod Out (ARO) Boron Concentration, Isothermal Temperature Coefficient (ITC), Control Rod Worth measurements and so on. KHNP-CRI has developed the Core Simulator for APR1400 (APR1400-CoSi) in order to improve the ability performing the LPPT. Especially, APR1400-CoSi has enhanced capability to calculate the full Core neutronic parameters by revising RAST-K that is three dimensional real time core kinetic program. APR1400-CoSi has been developed for education-training of Low Power Physics Test(LPPT). Particularly, APR1400-CoSi has an enhanced capability to calculate the full core neutronic parameters by revising RAST-K which is a three dimensional real time core kinetics program. Low Power Physics Test (LPPT) was performed using APR1400-CoSi and the results showed very similar values with the predicted ones. In other words, the initial core model of Shin-Kori Unit 3 in APR1400-CoSi system has been verified to be appropriate enough. Also, it was confirmed that the test range of Low Power Physics Test (LPPT) reamains effective even though the largest incremental bank reactivity is inserted in core by analyzing the power change during the rod SWAP test

  8. Verification of SAMG entry condition for APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Yun, Junghyun; Kim, Taewan; Kim, Jonghyun [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

    2013-10-15

    In the wake of the Fukushima accident, severe accident management has become important more than ever. While Emergency Operating Procedures (EOPs) focuses on cooling down the core during a design basis accident, the prime objective of severe accident management guideline (SAMG) is to prevent the release of radioactive material into the environment during a severe accident. Only one fixed value of core exit temperature (CET) has been applied for several decades to different types of nuclear power plants (NPPs) in Korea. Although the different types of NPPs have different cladding materials and system designs, the identical CET, i. e., 650 .deg. C, is applied as the entry condition to the SAMG of all the NPPs (except CANDU plants), i. e., Westinghouse type, OPR1000, and APR1400. In this paper, the transition point is re-evaluated for dominant severe accident sequences; station black-out (SBO), small break loss of coolant accident (SBLOCA), and me dium break loss of coolant accident (MBLOCA). In cases of SBO and SBLOCA, the current SAMG entry condition seems proper, while it needs to be reconsidered for MBLOCA case.

  9. Extended Station Blackout Coping Capabilities of APR1400

    Directory of Open Access Journals (Sweden)

    Sang-Won Lee

    2014-01-01

    Full Text Available The Fukushima Dai-ichi nuclear power plant accident shows that an extreme natural disaster can prevent the proper restoration of electric power for several days, so-called extended SBO. In Korea, the government and industry performed comprehensive special safety inspections on all domestic nuclear power plants against beyond design bases external events. One of the safety improvement action items related to the extended SBO is installation of external water injection provision and equipment to RCS and SG. In this paper, the extended SBO coping capability of APR1400 is examined using MAAP4 to assess the effectiveness of the external water injection strategy. Results show that an external injection into SG is applicable to mitigate an extended SBO scenario. However, an external injection into RCS is only effective when RCS depressurization capacity is sufficiently provided in case of high pressure scenarios. Based on the above results, the technical basis of external injection strategy will be reflected on development of revised severe accident management guideline.

  10. Modal analysis of an ECC duct for APR+ reactor barrel

    International Nuclear Information System (INIS)

    Advanced Power Reactor Plus (APR+) provides four Direct Vessel Injection (DVI) ducts on the reactor barrel to enhance the performance of Emergency Core Cooling System (ECCS). Several studies on safety analysis have verified the excellent performance of the DVI duct. In this study, from the viewpoint of mechanical integrity, modal analyses of two full-scaled DVI ducts have been presented; both numerical analysis and modal tests have been performed in air and water. It was found that the numerical simulation and modal test coincide with each other. The DVI duct is a thin shell of 5 mm thickness, so that harmonic responses to RCP blade passing frequencies should be checked. The dominant passing frequencies are known to be 20, 40, 60, 120 and 240 Hz. In addition, an interesting thing in this study is that added mass effect by coolant seems to be so significant that the natural frequency of the ducts under water could be considerably low as compared with those in air; the natural frequency under water is 60 % lower than that in air. (author)

  11. Study on Maintenance Personnel Development Plan For The Exported APR1400 Commissioning

    International Nuclear Information System (INIS)

    This paper indicates ways to develop maintenance personnel for the exported APR1400 commissioning. The exported APR1400 has not been experienced ay maintenance yet, and requirements for maintenance personnel have not been clarified yet. Based on sound maintenance experience, KEPCO Plant Service and Engineering Company (KEPCO KPS) has studied on maintenance training and career requirement to establish a development plan of the maintenance personnel for the exported nuclear power plant. By defining manpower and training requirement, and mobilization plan, we expect to secure reliability of the exported APR1400

  12. Fuel assembly design for APR1400 with low CBC

    Science.gov (United States)

    Hah, Chang Joo

    2015-04-01

    APR 1400 is a PWR (Pressurized Water Reactor) with rated power of 3983 MWth and 241 assemblies. Recently, demand for extremely longer cycle up to 24 months is increasing with challenge of higher critical boron concentration (CBC). In this paper, assembly design method of selecting Gd-rods is introduced to reduce CBC. The purpose of the method is to lower the critical boron concentration of the preliminary core loading pattern (PLP), and consequently to achieve more negative or less positive moderator temperature coefficient (MTC). In this method, both the ratio of the number of low-Gd rod to the number of high-Gd rod (r) and assembly average Gd wt% (w) are the decision variables. The target function is the amount of soluble boron concentration reduction, which can be converted to ΔkTARGET. A set of new designed fuel assembly satisfies an objective function, min [f =∑i (ΔkF A-Δki ) ] , and enables a final loading pattern to reach a target CBC. The constraints required to determine a set of Δk are physically realizable pair, (r,w), and the sum of Δk of new designed assemblies as close to ΔkTARGET as possible. New Gd-bearing assemblies selected based on valid pairs of (r,w) are replaced with existing assemblies in a PLP. This design methodology is applied to Shin-Kori Unit 3 Cycle 1 used as a reference model. CASMO-3/MASTER code is used for depletion calculation. CASMO-3/MASTER calculations with new designed assemblies produce lower CBC than the expected CBC, proving that the proposed method works successful.

  13. Fuel assembly design for APR1400 with low CBC

    Energy Technology Data Exchange (ETDEWEB)

    Hah, Chang Joo, E-mail: changhah@kings.ac.kr [Department of NPP Engineering, KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

    2015-04-29

    APR 1400 is a PWR (Pressurized Water Reactor) with rated power of 3983 MWth and 241 assemblies. Recently, demand for extremely longer cycle up to 24 months is increasing with challenge of higher critical boron concentration (CBC). In this paper, assembly design method of selecting Gd-rods is introduced to reduce CBC. The purpose of the method is to lower the critical boron concentration of the preliminary core loading pattern (PLP), and consequently to achieve more negative or less positive moderator temperature coefficient (MTC). In this method, both the ratio of the number of low-Gd rod to the number of high-Gd rod (r) and assembly average Gd wt% (w) are the decision variables. The target function is the amount of soluble boron concentration reduction, which can be converted to Δk{sub TARGET}. A set of new designed fuel assembly satisfies an objective function, min [f=∑{sub i}(Δk{sub FA}−Δk{sub i})], and enables a final loading pattern to reach a target CBC. The constraints required to determine a set of Δk are physically realizable pair, (r,w), and the sum of Δk of new designed assemblies as close to Δk{sub TARGET} as possible. New Gd-bearing assemblies selected based on valid pairs of (r,w) are replaced with existing assemblies in a PLP. This design methodology is applied to Shin-Kori Unit 3 Cycle 1 used as a reference model. CASMO-3/MASTER code is used for depletion calculation. CASMO-3/MASTER calculations with new designed assemblies produce lower CBC than the expected CBC, proving that the proposed method works successful.

  14. Uncertainty analysis of occupational radiation exposure dose for APR1400 design certification

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Kyo Min; Lee, Chong Hui; Lee, Dong Su; Kim, Byung Il; Kang, Sang Ho [Korea Electric Power Corporation (KEPCO) E and C Inc., Seoul (Korea, Republic of); Son, Jung Gwon [Korea Hydro and Nuclear Power (KHNP) Central Research Institue (CRI), Gyeongju (Korea, Republic of)

    2014-11-15

    While it is required to include the anticipated Occupational Radiation Exposure (ORE) in the DC application, the ORE data for APR1400 is not available, since the first APR1400 is under construction in Korea. Therefore, this study performs the uncertainty analysis to estimate the expected ORE dose for APR1400 DC using the experience data from the operating plant in Korea based on the methodology specified in NRC Regulatory Guide(RG) 8.19. According to the results, if the design improvements are taken into account, it is found that the median value of APR1400 ORE dose, even for the case of 95 percentile value is within the design target of 1 man-Sv.

  15. Development of human factors validation system for the advanced control room of APR1400

    International Nuclear Information System (INIS)

    A human factors validation system for the main control room (MCR) of Advanced Power Reactor 1400 MWe (APR1400) has been developed as it adopts digitalized human-system interfaces (HSIs). The integrated validation system is composed of process/plant models, HSIs, and the human performance evaluation support system (HUPESS). A real-time thermal-hydraulic code, RELAP5 R/T, was used and modified to simulate the dynamic characteristics of the APR1400, and simulation software, 3KeyMaster, was used to model the balance of plant systems. The HSIs developed in this study include all facilities in the APR1400 MCR, such as large display panels, 3 identified operator workstations, and a safety console. In addition, the remote shutdown workstation has been developed. The display systems in the HSIs have been developed using ProcSee, which is a software tool for developing and displaying dynamic graphical user interfaces. This paper describes the configurations of HSIs including display systems, the dynamic models of the APR1400 simulator, the instructor station, and the HUPESS. This paper also presents the results of plant simulation performance tests at transient compared with the results of RELAP5/MOD3.3 calculations. The human factors validation system for the advanced control room of APR1400 provides high degrees of physical, functional, and dynamic fidelities, and can be used in the validation process of the APR1400 HSI design. (author)

  16. COMENTARIU LA ARTICOLUL FISTULE CHOLÉCYSTO - DUODÉNALE E. Christide - Revista de Chirurgie 1938; 7 - 8/41: 579 - 585

    Directory of Open Access Journals (Sweden)

    Nicolae M. Constantinescu

    2012-11-01

    dispoziţie: avivareamarginilor cu sutură transversală în 2planuri, patch cu seroasă de jejun,anastomoză duodeno-jejunală latero-terminală pe ansă în Y Roux. În cazul unuiduoden II strâmtorat se poate executa ogastroentero-anastomoză.Articolul pe care îl comentez şidiscuţiile pe care le-a suscitat la Societateade Chirurgie din Bucureşti în urmă cu treisferturi de secol ne aduc în memorie 4 dinmarii chirurgi ai primei jumătăţi a sec XX.Astfel în spatele lui Christide îlvedem peingeniosul Ernest Juvara, chiar dacă la oraaceea nu mai era în viaţă, bolnavul prezentatde St.Jianu a fost rezolvat de IacobIacobovici, cazul prezentat de Blassian a fostoperat de Traian Nasta iar cel comentat deGh. Gatoschi a fost operat deVladimirBuţureanu la Iaşi.Observaţia clinică a lui Christide areca particularităţi istoricul care precizeazăeliminarea de calculi prin fecale, semn carenu este patognomonic pentru fistulă-şi apoimaniera în care a folosit perete din colecistpentru aacoperi defectul duodenal. Pentrupolul biliar nu a făcut nici o manevră deidentificare şi ligatură a canalului cistic,motiv care explică biliragia postoperatorie,care a durat cu intermitenţă patru luni şiAdresa de corespondenţă: Prof.Dr.N.M. ConstantinescuUniversitatea de Medicină şi Farmacie „Carol Davila” Bucureştie-mail: nae_constantinescu@yahoo.com412Jurnalulde Chirurgie (Iaşi, 2012, Vol. 8, Nr. 4jumătate. Actualmente cazul ar fi beneficiatmult mai devreme de o papilo-sfincterotomieendoscopică.În cazul prezentat de Ştefan Jianu eravorba de o fistulă ulceroasă colecisto-duodenală între fundul colecistului şigenunchiul superior duodenal, la caregastrectomia cu anastomoză gastro-jejunalăapus în repaus fistula de contactul cualimente, lucru pe care nu-l reuşise GEAefectuată anterior şi care se dovedisenefuncţională.Bolnavul prezentat de Blassian şi carea fost operat de Traian Nasta este un caztipic de fistulă colecisto-duodenală deorigine

  17. Economics enhancement of APR1400 through the application of new construction methods

    International Nuclear Information System (INIS)

    The development of APR1400 (formerly KNGR) project is one of Korea's national G-7 projects, sponsored by the government and KHNP (Korea Hydro and Nuclear Power Co., Ltd.). APR1400, an evolutionary standard reactor with a thermal output of 4000MWt, upgrades the safety and economic competitiveness of nuclear power, incorporating cutting-edge advanced technologies, while standing on the proven experience of Optimized Power Reactor 1000(OPR1000, formerly KSNP) design. APR1400 has been adopted as the design for Shin-Kori Units 3 and 4. APR1400 development project consisted of three phases in order to check and make only necessary adjustments at the end of each phase and the standard design certification (DC) was issued in May 2002. The project set up the top-tier requirements for the design's safety, economy, operability, maintainability, and construct ability in the earliest design stage. The requirements have been evaluated periodically during the design process, and the results of each evaluation were reflected in the final design. Shin-Kori Units 3 and 4 are the first APR1400 projects, and will be built near the Kori NPP site, where four units are currently in operation and two OPR1000 (Improved Korean Standard Nuclear Power Plant) units called Shin-Kori Units 1 and 2 are under construction. Shin-Kori Units 3 and 4 will be constructed based on APR1400 standardized design, while incorporating the site characteristics and construction and operation experiences of OPR1000. This paper describes new construction methods to improve economics and construct ability of APR1400 to meet the target schedule, which is set to 41.5 months from the first concrete pouring to the fuel loading for the Nth plant. The new construction methods consist of 'Open Top Method' for installation of major NSSS equipment, 'Large Modularization' for the Building Structures, Reactor Vessel Internals and Major Components and deck plate method, etc

  18. Experimental and MARS code simulation of DVI line 25% and 50% break LOCAs using SNUF for APR1400

    International Nuclear Information System (INIS)

    APR1400, is an evolutionary PWR (Pressurized Water Reactor) based on the well-proven OPR1000 design. The APR1400 has adopted DVI (Direct Vessel Injection) system instead of CLI (Cold Leg Injection) system as advanced safety features of ECCS (Emergency Core Cooling System). The configuration of the improved ECCS in the APR1400 is completely different from that in the OPR1000 in which pipes for the safety water injection are connected to the cold leg. In APR1400, the safety water injection pipes are directly connected to the RPV (Reactor Pressure Vessel). Thus, the safety water injection system in the APR1400 is called the DVI (Direct Vessel Injection) system. Moreover, safety water injections by the HPSI (High Pressure Safety Injection) pumps are mechanically separately in the APR1400.

  19. Assistant Personal Robot (APR): Conception and Application of a Tele-Operated Assisted Living Robot.

    Science.gov (United States)

    Clotet, Eduard; Martínez, Dani; Moreno, Javier; Tresanchez, Marcel; Palacín, Jordi

    2016-04-28

    This paper presents the technical description, mechanical design, electronic components, software implementation and possible applications of a tele-operated mobile robot designed as an assisted living tool. This robotic concept has been named Assistant Personal Robot (or APR for short) and has been designed as a remotely telecontrolled robotic platform built to provide social and assistive services to elderly people and those with impaired mobility. The APR features a fast high-mobility motion system adapted for tele-operation in plain indoor areas, which incorporates a high-priority collision avoidance procedure. This paper presents the mechanical architecture, electrical fundaments and software implementation required in order to develop the main functionalities of an assistive robot. The APR uses a tablet in order to implement the basic peer-to-peer videoconference and tele-operation control combined with a tactile graphic user interface. The paper also presents the development of some applications proposed in the framework of an assisted living robot.

  20. Cosmetische ingrepen tijdens orthognathische chirurgie

    NARCIS (Netherlands)

    Jansma, Johan; Schepers, R H; Vissink, A

    2016-01-01

    The goal of a combined orthodontic-surgical treatment is to correct the dysgnathia and malocclusion and thereby achieve an improvement of function. As a supplement to osteotomy, enhancement of facial aesthetics is increasingly being used to gain more harmony in the face and/or to achieve facial reju

  1. Evaluation of ex-vessel steam explosion load for APR1400 using IFCI

    International Nuclear Information System (INIS)

    The load of ex-vessel steam explosion for APR1400 is evaluated using the IFCI 6.0 code developed by US NRC. The IFCI code is applied to analyse the FCI experiments of FARO-28, KROTOS-44 and TROI-13 as a code V/V process. The load of ex-vessel steam explosion for APR1400 is calculated based on the conditions applied during the code V/V and the load was compared with the analysis result of licence. The IFCI analysis result shows that the integrity of cavity might not be guaranteed once a steam explosion occurs and the result is in contrast with that of licence

  2. Engineering and Directed Evolution of a Ca2+ Binding Site A-Deficient AprE Mutant Reveal an Essential Contribution of the Loop Leu75–Leu82 to Enzyme Activity

    Directory of Open Access Journals (Sweden)

    Eliel R. Romero-García

    2009-01-01

    G102D. These results support the proposal that in addition to function as a calcium binding site, the loop that connects β-sheet e3 with α-helix c plays a structural role on enzyme activity of AprE from B. subtilis 168.

  3. The Alberta Pregnancy Outcomes and Nutrition (APrON) cohort study : rationale and methods

    NARCIS (Netherlands)

    Kaplan, Bonnie J.; Giesbrecht, Gerald F.; Leung, Brenda M. Y.; Field, Catherine J.; Dewey, Deborah; Bell, Rhonda C.; Manca, Donna P.; O'Beirne, Maeve; Johnston, David W.; Pop, Victor J.; Singhal, Nalini; Gagnon, Lisa; Bernier, Francois P.; Eliasziw, Misha; McCargar, Linda J.; Kooistra, Libbe; Farmer, Anna; Cantell, Marja; Goonewardene, Laki; Casey, Linda M.; Letourneau, Nicole; Martin, Jonathan W.

    2014-01-01

    The Alberta Pregnancy Outcomes and Nutrition (APrON) study is an ongoing prospective cohort study that recruits pregnant women early in pregnancy and, as of 2012, is following up their infants to 3 years of age. It has currently enrolled approximately 5000 Canadians (2000 pregnant women, their offsp

  4. CFD Simulation of Acoustic-Induced Vibration in Main Steam Line of APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Lim, Sang Gyu; Kim, Tae Jun; Kim, Han Gon [Korea Hydro and Nuclear Power, Daejeon (Korea, Republic of)

    2012-05-15

    In recently, many boiling water reactors (BWRs) implement extended power uprate (EPU) to increase economic benefits. After EPU, Quad Cities power plant has been experienced damage of steam dryers due to acoustic-induced vibration. Acoustic resonance is produced by the interaction between the sound field and an unstable shear layer when the dry steam flows across the closed branch pipes such as safety relief valve(SRV). The unsteady vortices are separated at the leading edge of branch pipe and generated fluctuating pressure wave. After this experience, US-NRC issued that the licensee for new type of reactor should perform a vibration assessment program for an adverse flow effect in the main steam line in accordance with regulatory guideline 1.20 revision 3. In Korea, KHNP CRI implements comprehensive vibration program for steam generator of APR1400 and evaluates acoustic-induced vibration in main steam line using a commercial CFD code, ANSYS CFX 13.0. This paper deals with benchmark analysis to obtain applicability and reliability of commercial code for prediction of acoustic resonance phenomenon in case of single branch pipe test. Based on the benchmark analysis, analysis of main steam line in APR1400 plant is performed. In case of APR1400, five main steam safety valves are installed in the main steam line. Finally, this paper shows a prediction result of acoustic induced vibration characteristic in main steam system of APR1400

  5. An integral effect test on the feedwater line break of APR1400 with the ATLAS facility

    International Nuclear Information System (INIS)

    An integral effect test on the feedwater line break (FLB) was performed with the ATLAS facility for an APR1400 as a typical secondary system transient. The objectives of the present FLB tests are to understand the accident progression of the FLB scenario based on the APR1400 preliminary safety analysis report (PSAR) and to assess the prediction capability of system analysis codes such as the MARS, RELAP5, TRACE and SPACE. The main concern of the present FLB test is the peak RCS pressure and the major parameters affecting the peak RCS pressure are the break size, the break location, potential for reverse flow, initial pressurizer level and the initial SG level. The present test is performed for a break on the pipe connected to the economizer with a typical break size. The initial steady-state conditions and the sequence of event of FLB scenario for the APR1400 were successfully simulated with the ATLAS facility. In the present paper, major thermal-hydraulic phenomena such as the system pressures, the collapsed water levels, and the break flow rate are presented and discussed. It could be concluded that the APR1400 has the capability of coping with the hypothetical FLB scenario with an adequate set of controlling devices and proper setpoints. This integral effect test data could also be used to evaluate the prediction capability of existing safety analysis codes of MARS, RELAP5 and SPACE and to identify any code deficiency for an FLB simulation. (author)

  6. Greta Kaits 9. apr. 1928 - 29. aug. 1946 : [luuletused] / Mats Traat

    Index Scriptorium Estoniae

    Traat, Mats, 1936-

    2008-01-01

    Sisu : Greta Kaits 9. apr. 1928 - 29. aug. 1946 ; Villem Hänilane 1898 - 1952 ; Peeter Pedak 1897 - 1953 ; Max Äidse 1903 - 1959 ; Lavinia Laidam ; Buchard Pruus ; Sergei Krivokopõtov ; Allan Luht 5. VII 1962 - 17. V 2007 ; Karl Saarmets 9. III 1924 - 14. IX 1981 ; Raimo Ritsik

  7. Preliminary System Response Analysis of Rod Ejection Accident for APR1000

    International Nuclear Information System (INIS)

    Korea Electric Power Co. (KEPCO) has designed the Advanced Power Reactor 1000 (APR1000) plants implementing the advanced safety features to Optimized Power Reactor 1000 (OPR1000) plants. Prior to developing the detail design, the preliminary design project has been launched since the end of 2009 as a feasibility study. In spite of some difference in safety- related design concepts of two plant types, they could be treated as the same plants considering the main features or systems. In this study, the rod ejection accident (REA) event was analyzed using Korea Non-LOCA Analysis Package (KNAP) hot spot model (HSM) for APR1000 to examine the feasibility of the design concepts and the results were compared with those values calculated by the Safety Analysis Report (SAR) conditions of typical OPR1000 plants. Through the study, it was concluded that the design concepts and the analysis package could be applicable on the view point of REA

  8. External Reactor Vessel Cooling Strategy Application for APR1400 Station Blackout Scenarios

    Energy Technology Data Exchange (ETDEWEB)

    Tran, Quang Diep Khanh; Oh, Seung Jong [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of); Ro, Seo Mi [KHNP Central Research Institute, Daejeon (Korea, Republic of)

    2013-10-15

    In Korea, all NPPs implemented post-Fukushima measures. In U. S., the approach is to expand B5b strategy to build up FLEX strategies utilizing portable equipment. With portable pumps and connections, one can mitigate and respond to wide range of accidents. In this study, we examined the feasibility of cavity flooding using portable pumps for ERVC and its effectiveness in responding to extended SBO scenarios. The external reactor vessel cooling (ERVC) is one of important severe accident management (SAM) strategies adopted for APR1400. ERVC strategy is to remove decay heat from molten corium in lower plenum by submerging the vessel with water. The strategy requires water injection into cavity and APR1400 uses shutdown cooling pumps for this purpose, requiring electricity. Recent Fukushima accident shows the importance of mitigation capability against extended SBO scenarios.

  9. Conceptual Design of the Top Mounted In-core Instrumentation for APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Bae, Taehyun; Bae, Jaehyun; Kim, Jongmin; Maeng, Cheolsoo; Kim, Hyunmin; Lee, Daehee [KEPCO Engineering and Construction, Daejeon (Korea, Republic of)

    2015-10-15

    Safety issue for nuclear power plant is reviewed. One of the main issue is Top Mounted In-core Instrumentation (TM-ICI). TM-ICI has the advantage of the structural integrity on the reactor bottom head during severe accident. This research about adopting the TM-ICI for APR1400 has been performed to have this advantage. Designing the nuclear power plant, safety issue is very important, and TM-ICI is one of the main issue. For the research of the TM-ICI, APR1400 has been reviewed for possibility of the TM-ICI and the results are as follows: The ICI nozzle head penetration shall be located outside of the CEDM nozzles and Two types of CEAs shall be unified into one type.

  10. The Gravity Makeup on the LORHR Event during Mid-loop Operation for APR1400

    International Nuclear Information System (INIS)

    This paper is to investigate means of the available gravity makeup after the event to prevent or sustain the core uncovery and fuel failure for the typical advanced power reactor nuclear power plants (APR1400). Unlike the OPR1000 (optimized power reactor 1000 nuclear power plants), the refueling water storage tank of APR1400 cannot be used for gravity makeup since it is located on the bottom of the containment with a lower elevation than the reactor vessel. So, the other means of gravity makeup and their effect on the core uncovery are accounted. The use of the water used for the cask loading pit (CLP) during refueling or the safety injection line filling tank (SIFT), which are not designed for gravity makeup during the event, and safety injection tanks (SITs) are considered as the alternative source of makeup feed. The results show that gravity makeup of a SIT provides a sufficient operator action time for the LORHR with the station black out (SBO) during the mid-loop operation for the APR1400. From the LORHR event analysis, the effective means of gravity makeup for APR1400 to cope with this event concurrent loss of all AC power is determined as the gravity feed using SITs. Other means for gravity makeup using CLP or SIFT, which are not designed to mitigate the LORHR event, are evaluated as not effective to the event due to the large flow resistances and the low elevation head to overcome the system pressure increase during the LORHR. The use of one SIT and two SITs for the LORHR provides the core uncovery times as 3 hr 8 min and 4 hr 32 min extending 1 hr 15 min and 2 hr 38 min from the base case, respectively

  11. The Gravity Makeup on the LORHR Event during Mid-loop Operation for APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Cheol Woo; Lee, Yong Hee; Lee, Gyu Cheon; Kim, Shin Whan [KEPCO, Daejeon (Korea, Republic of)

    2015-05-15

    This paper is to investigate means of the available gravity makeup after the event to prevent or sustain the core uncovery and fuel failure for the typical advanced power reactor nuclear power plants (APR1400). Unlike the OPR1000 (optimized power reactor 1000 nuclear power plants), the refueling water storage tank of APR1400 cannot be used for gravity makeup since it is located on the bottom of the containment with a lower elevation than the reactor vessel. So, the other means of gravity makeup and their effect on the core uncovery are accounted. The use of the water used for the cask loading pit (CLP) during refueling or the safety injection line filling tank (SIFT), which are not designed for gravity makeup during the event, and safety injection tanks (SITs) are considered as the alternative source of makeup feed. The results show that gravity makeup of a SIT provides a sufficient operator action time for the LORHR with the station black out (SBO) during the mid-loop operation for the APR1400. From the LORHR event analysis, the effective means of gravity makeup for APR1400 to cope with this event concurrent loss of all AC power is determined as the gravity feed using SITs. Other means for gravity makeup using CLP or SIFT, which are not designed to mitigate the LORHR event, are evaluated as not effective to the event due to the large flow resistances and the low elevation head to overcome the system pressure increase during the LORHR. The use of one SIT and two SITs for the LORHR provides the core uncovery times as 3 hr 8 min and 4 hr 32 min extending 1 hr 15 min and 2 hr 38 min from the base case, respectively.

  12. An Experimental Investigation on APR1400 Penetration Weld Failure by Metallic Melt

    International Nuclear Information System (INIS)

    The penetrations are considered as the most vulnerable parts with respect to the reactor vessel failure when a core melt severe accident occurs and the corium reaches the lower head. Penetration tube failure modes can be divided into two categories; tube ejection out of the vessel lower head and rupture of the penetration tube outside the vessel. Tube ejection begins with degrading the penetration tube weld strength to zero as the weld is exposed to temperatures as high as the weld melting temperature, which is called weld failure, and then overcoming any binding force in the hole in the vessel wall that results from differential thermal expansion of the tube and vessel wall. Tube rupture assumes that the debris bed has melted the instrument tube inside the reactor and melt migrates down into the tube to a location outside the vessel wall where a pressure rupture can occur, thus breaching the pressure boundary. In the present paper, we have a focus on the tube ejection failure mode, specifically on the APR1400 weld failure by direct contact with a metallic melt. The objective is to investigate experimentally the ablation kinetics of an APR1400 penetration weld during the interactions with a metallic melt and to suggest the modification of the existing weld failure model. This paper involves the interaction experiments of two different metallic melts (metallic corium and stainless steel melts) with a weld specimen, and rough estimation of weld failure time. The interaction experiments between the metallic melts and an APR1400 penetration weld were performed to investigate the ablation kinetics of the penetration weld. Metallic corium and stainless steel melts were generated using an induction heating technique and interacted with a penetration weld specimen. The ablation rate of the weld specimen showed a range from 0.109 to 0..244 mm/s and thus the APR1400 penetration weld was estimated to be failed at hundreds of times after the interaction with the melt

  13. Critical heat flux for APR1400 lower head vessel during a severe accident

    International Nuclear Information System (INIS)

    Highlights: ► Studied boiling on downward-facing hemispherical vessel with asymmetric thermal insulator. ► Scaled the APR1400 lower head linearly down by 1/10 including ICI tubes and shear keys. ► Performed thermal analysis using ANSYS V11.0 to determine the internal temperature and heat flux. ► Performed tests to obtain the CHF with saturated demineralized water at atmospheric pressure. ► Measured CHF accounting for 3D random flow effect expected in the APR1400 application. -- Abstract: Corium Ablation Stopper Apparatus (CASA) has a downward-facing hemispherical vessel and geometrically asymmetric thermal insulator of the Advanced Power Reactor 1400 MWe (APR1400) scaled linearly down by 1/10, as well as sixty-one in-core instrumentation (ICI) tubes and four shear keys. The heated vessel plays a pivotal role in CASA depending on the configuration of the oxide pool and metal layer to bring about the focusing effect expected of a molten pool in the lower head during a severe accident. The heated vessel was designed through a trial-and-error method and thermal analysis. Thermal analysis was performed using ANSYS V11.0 to investigate the effect of the internal temperature and heat flux on the integral hemispherical copper vessel. The CASA tests were carried out to obtain the critical heat flux (CHF) with saturated and demineralized water at the atmospheric pressure (0.1 MPa). The CHF in the metal layer through the hemispherical channel was found to be lower than that in the ULPU-2400 configuration V data through the streamlined thermal insulator. The experimental CHF was measured and obtained through the CASA hemispherical heated surface accounting for the three-dimensional random flow effect expected in the APR1400 application

  14. APR-5000-XLS阵列封装返工系统

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    APR-5000-XLS阵列封装返工系统可处理BGA,CSP,LGA(Land Grid Army),Micro SMD,MLF(Micro Lead Frame),BCC(Bumped Chip Component)多种封装。其可处理的板尺寸达610mm×610mm(24.5”×24.5”),厚度达6.35mm(0.25”)。

  15. Development of the Diverse Means for Reactor Shutdown Function of EU-APR1400

    International Nuclear Information System (INIS)

    This paper provides general descriptions of the EBS focusing on basic design characteristics such as system function, configuration and operation, and presents results from the preliminary verification of system performance. The diverse means for the reactor shutdown function of EU-APR1400 have been developed to comply with the diversity principle of the European design requirements of a new nuclear power plant. The preliminary verification of the EBS performance was done by the ATWS analysis. The analysis results show that the EBS was designed properly. Diversity is the fundamental principle in safety system design of a new nuclear power plant, which uses different mitigation measures to provide diverse ways of responding to a significant event. Regarding the diversity principle, EU-APR1400 (European APR1400) safety system should be in accordance with European design requirements. EBS (Emergency Boration System) is designed to provide the diverse means to shut down the reactor against ATWS (Anticipated Transient Without Scram) and to mitigate the event consequences in the EUAPR1400

  16. Assistant Personal Robot (APR): Conception and Application of a Tele-Operated Assisted Living Robot.

    Science.gov (United States)

    Clotet, Eduard; Martínez, Dani; Moreno, Javier; Tresanchez, Marcel; Palacín, Jordi

    2016-01-01

    This paper presents the technical description, mechanical design, electronic components, software implementation and possible applications of a tele-operated mobile robot designed as an assisted living tool. This robotic concept has been named Assistant Personal Robot (or APR for short) and has been designed as a remotely telecontrolled robotic platform built to provide social and assistive services to elderly people and those with impaired mobility. The APR features a fast high-mobility motion system adapted for tele-operation in plain indoor areas, which incorporates a high-priority collision avoidance procedure. This paper presents the mechanical architecture, electrical fundaments and software implementation required in order to develop the main functionalities of an assistive robot. The APR uses a tablet in order to implement the basic peer-to-peer videoconference and tele-operation control combined with a tactile graphic user interface. The paper also presents the development of some applications proposed in the framework of an assisted living robot. PMID:27136552

  17. Assistant Personal Robot (APR: Conception and Application of a Tele-Operated Assisted Living Robot

    Directory of Open Access Journals (Sweden)

    Eduard Clotet

    2016-04-01

    Full Text Available This paper presents the technical description, mechanical design, electronic components, software implementation and possible applications of a tele-operated mobile robot designed as an assisted living tool. This robotic concept has been named Assistant Personal Robot (or APR for short and has been designed as a remotely telecontrolled robotic platform built to provide social and assistive services to elderly people and those with impaired mobility. The APR features a fast high-mobility motion system adapted for tele-operation in plain indoor areas, which incorporates a high-priority collision avoidance procedure. This paper presents the mechanical architecture, electrical fundaments and software implementation required in order to develop the main functionalities of an assistive robot. The APR uses a tablet in order to implement the basic peer-to-peer videoconference and tele-operation control combined with a tactile graphic user interface. The paper also presents the development of some applications proposed in the framework of an assisted living robot.

  18. Development of Environmentally-Assisted Fatigue Monitoring System for Advanced Power Reactors (APR1400)

    Energy Technology Data Exchange (ETDEWEB)

    Park, June Soo; Kim, Yeon Jeong; Kang, Sun Yeh; Yoon, Ki Seok; Choi, Taek Sang [KEPCO-E and C, Daejeon (Korea, Republic of)

    2013-10-15

    This paper introduces an EAF monitoring system developed for Shin-Kori Nuclear Power Plant (NPP), Units 3 and 4 which are the first two reactors of the APR1400 model. The EAF monitoring system has been developed for Shin-Kori NPP, Units 3 and 4, and is ready for an application for the plant lifetime. It is expected that the plant fatigue management can be effectively fulfilled, and the structural integrity of the critical components assured by an implementation of the fatigue monitoring system from the beginning of the lifetime. When fatigue analyses including the effects of the Light-Water Reactor (LWR) environment are applicable, plant designers address the environmentally-assisted fatigue (EAF) for Class 1 reactor pressure boundary components. The environment factor (F{sub en}) method has been endorsed by the U. S. Nuclear Regulatory Commission for evaluating fatigue analyses to address the environmental effects, and this method considers four major variables in addition to the traditional air-fatigue analyses: Material temperature, dissolved oxygen content of coolant, sulfur (S) content of material, and strain rate at the material points of interest. APR1400 nuclear power plants are designed to the requirements of the enhanced plant safety, availability and performance criteria for a 60 year design life. To better manage the material degradation and structural integrity of the pressure boundary components, a fatigue monitoring system has been developed for APR1400 NPPs, which is capable to monitor the EAF damage during the plant lifetime.

  19. The Alberta Pregnancy Outcomes and Nutrition (APrON) cohort study: rationale and methods.

    Science.gov (United States)

    Kaplan, Bonnie J; Giesbrecht, Gerald F; Leung, Brenda M Y; Field, Catherine J; Dewey, Deborah; Bell, Rhonda C; Manca, Donna P; O'Beirne, Maeve; Johnston, David W; Pop, Victor J; Singhal, Nalini; Gagnon, Lisa; Bernier, Francois P; Eliasziw, Misha; McCargar, Linda J; Kooistra, Libbe; Farmer, Anna; Cantell, Marja; Goonewardene, Laki; Casey, Linda M; Letourneau, Nicole; Martin, Jonathan W

    2014-01-01

    The Alberta Pregnancy Outcomes and Nutrition (APrON) study is an ongoing prospective cohort study that recruits pregnant women early in pregnancy and, as of 2012, is following up their infants to 3 years of age. It has currently enrolled approximately 5000 Canadians (2000 pregnant women, their offspring and many of their partners). The primary aims of the APrON study were to determine the relationships between maternal nutrient intake and status, before, during and after gestation, and (1) maternal mood; (2) birth and obstetric outcomes; and (3) infant neurodevelopment. We have collected comprehensive maternal nutrition, anthropometric, biological and mental health data at multiple points in the pregnancy and the post-partum period, as well as obstetrical, birth, health and neurodevelopmental outcomes of these pregnancies. The study continues to follow the infants through to 36 months of age. The current report describes the study design and methods, and findings of some pilot work. The APrON study is a significant resource with opportunities for collaboration.

  20. Single-tube condensation experiment in Passive Auxiliary Feedwater System of APR1400+

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Chang Wook; No, Hee Cheon; Yun, Bong Yo; Jeon, Byong Guk [Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of)

    2012-05-15

    Conventional Korean nuclear power plants, Advanced Power Reactors (APR), are characterized by an active cooling system. However, Active cooling system may not prevent significant damage without any AC power source available for its operation as vividly illustrated through the recent Fukushima incident. In the APR1400+ to be designed, an independent passive cooling system was added in order to overcome the aforementioned shortcomings. In the Passive Auxiliary Feedwater System (PAFS), gravity force and density difference between steam and water are used. The system comprises of 240 condensation tubes to efficiently remove decay heat. Before applying the PAFS to APR1400+, the system's safety and heat removal performance must be verified. The present study experimentally evaluates the heat removal performance of a single tube in the PAFS. The objectives of SCOP (Single-tube Condensation experiment facility of PAFS) are the evaluation of the heat removal performance in the tube of the PAFS and database construction under various tube designs and test conditions. Reaching these objectives, we developed advanced measurement techniques for the amount of moisture, heat flux, and water film thickness.

  1. Containment Performance Analysis with Large Break LOCA for EU-APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, Do Hyun; Lee, Keun Sung; Kim, Yong Soo [KHNP CRI, Daejeon (Korea, Republic of)

    2013-10-15

    In this paper for containment performance analysis, the containment pressurization analysis is performed and thermo-hydraulic response analysis of containment structure is carried out to provide basic understanding of containment transient states under a severe accident sequence. Especially, in EU-APR1400 design, to reduce containment pressure and temperature, Severe Accident Containment Spray System (SACSS) is designed to be actuated automatically when Core Exit Temperature (CET) reaches 922 K (649 .deg. C). The containment performance analysis was carried on LBLOCA sequence for EU-APR1400 with SACSS through MAAP code. If SACSS is actuated when CET reaches 922 K (649 .deg. C) , the containment pressure and temperature decrease to a sufficient low level. The predicted atmospheric pressure of containment will not exceed the ultimate pressure capacity (UPC) and have a sufficient margin to it even though the UPC of the reference plant (Shin-Kori Units 3 and 4) is used instead because the UPC calculation for EU-APR1400 has not been completed. The largest load on the containment by LBLOCA is estimated at 306.1 kPa. Thus the margin to UPC is estimated to be 330 % in comparison with 1.329 MPa as UPC for the reference plant.

  2. Analytical Assessment of Environmental Impact for APR1400DC UHS Cooling Tower

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jaiho [KHNP-Central Research Institute, Daejeon (Korea, Republic of)

    2015-05-15

    Hot process water is pumped from the plant process to the cooling towers. Heat is rejected through evaporation of the process water, interacting with ambient air blown upward by fans.. Plumes generated from exit ports of the cooling tower may have adverse effects on the environment, such as deposition of cooling tower drift release, fogging, icing, shadowing, and ground-level temperature and humidity increase. These kinds of environmental impact of the cooling tower are linked closely with the dispersion of the cooling tower plumes. In this respect, predicting the behavior of the plumes has become one of the most important issues in the environmental assessments of the cooling towers. The SACTI (seasonal/annual cooling tower impact) model is an analytical tool to predict the environmental effect of cooling tower, which was developed by Argonne National Laboratory and University of Illinois with support from EPRI (electric power research institute). The initial version of SACTI has been widely used to assess the environmental effect of cooling towers in many industrial fields such as steam power plants and NPPs. Guo et. al. investigated impact of heat rejection and cooling tower height on plume dispersion using the SACTI model, for the purpose of the future construction of inland NPPs. They found that increasing cooling tower height decreases the plume length and height frequencies. Their simulation results showed that the increase in heat rejection increases the plum radius frequency. The APR1400DC is an advanced light water reactor developed for the purpose of NRC-DC (design certification). The cooling towers for APR1400DC UHS consist of two linear mechanical draft cooling towers (LMDCTs). The LMDCT for APR1400DC UHS is conceptually designed because the plant site has not been decided yet. In the present study, the dependency of plume dispersion on the number of cooling towers is investigated using SACTI-2-beta, for predicting annual environmental effect of APR

  3. Consideration of MAAP 5.0.2 ESF Model Characteristics for APR1400 NPP

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Mi Ro; Kim, Hyeong Taek [KHNP-CRI, Daejeon (Korea, Republic of)

    2014-10-15

    After the Fukushima accident, EPRI has developed the MAAP (Modular Accident Analysis Program) version 5 that is expected to make up the limitation of MAAP4, that is to say, the appropriateness of the model for the severe accident phenomena and the applicability to the phenomena in the spent fuel pool and the halfloop operation. Up to now, the newest version of MAAP is 5.0.2 (Build 5020000) that was released officially in December, 2013. In addition to this, it is expected that MAAP 5.0.3 version will be published sooner or later. As a kind of post-Fukushima measures, KHNP is developing the probabilistic safety assessment (PSA) and severe accident management guideline (SAMG) for low power and shutdown (LPSD) mode and MAAP 5.0.2 should be used in these projects as a major analysis program. So, first of all, it is necessary that the parameter file for domestic NPP should be upgraded as current Ver. MAAP4 to Ver. MAAP 5.0.2. KHNP has developed the draft version of parameter file for APR1400 type NPP and is being upgraded continuously. The Engineering Safety Features (ESF) model is one of the unique features of MAAP. In this study, we try to share the general information of the MAAP ESF model and the specific characteristics of APR1400 ESF model based on the newly developed MAAP 5.0.2 parameter file. Currently, while developing the LPSD PSA and LPSD SAMG as a kind of post-Fukushima measures, KHNP have the plan in order to upgrade the old parameter file based on MAAP4 to that based on MAAP5.0.2 for all domestic nuclear power plants. And, as the first effort, we are developing the MAAP 5.0.2 parameter file for APR1400 type NPP. In this study, we tried to develop the more accurate and reasonable ESF model of APR1400. In this process, we can find the distinctions and characteristics of specific ESF model and generalized ESF model of MAAP5.0.2. Also, we can eliminate the confusing concepts existed in the two models. So, it is judged that the newly developed MAAP5

  4. Evaluation of the Main Steam Line Break Accident for the APR+ Standard Design using MARS-KS

    International Nuclear Information System (INIS)

    As a part of licensing evaluation of the APR+ (Advanced Power Reactor +) standard design, Korea Institute of Nuclear Safety(KINS) performed safety evaluation of the APR+ Standard Safety Analysis Report(SSAR). The results of the safety evaluation of the APR+ Main Steam Line Break(MSLB) accident is presented for the most limiting post-trip return-to-power case with the single failure assumption of the Loss Of Offsite Power(LOOP). MARS-KS regulatory safety analysis code has been used to evaluate safety as well as the system behavior during MSLB accident. The MARS-KS analysis results are compared with the results of the MSLB safety analysis presented in the SSAR of the APR+. Independent safety evaluation has been performed using MARS-KS regulatory safety analysis code for the APR+ MSLB accident inside containment for the limiting case of the full power post-trip return-to-power. The results of MARS-KS analysis were compared with the results of the MSLB safety analysis presented in the APR+ SSAR. Due to higher cooldown of the MARS-KS analysis, the MARS-KS analysis results in a higher positive reactivity insertion into the core by the negative moderator and fuel temperature reactivity coefficients than the APR+ SSAR analysis. Both results show no return-to-power during the limiting case of the MSLB inside containment. However, APR+ SSAR moderator temperature reactivity insertion should be evaluated against the MARS-KS moderator density reactivity insertion for is conservatism. This study also clearly shows asymmetric thermal hydraulic behavior during the MSLB accident at intact and affected sides of the downcomer and the core. These asymmetric phenomena should be further investigated for the effects on the system design

  5. Diverse Design Features of EU-APR1400 for Residual Heat Removal Function with Open RCS

    International Nuclear Information System (INIS)

    Diversity is the fundamental principle in safety system design of new nuclear power plants, which uses different mitigation measures to provide diverse ways of responding to a significant event. Regarding the diversity principle, EU-APR1400 (European APR1400) safety system should be in accordance with European design requirements. This paper provides how the core residual heat can be removed with open RCS (Reactor Coolant System) closure head condition using diverse cooling systems assuming a loss of SCS (Shutdown Cooling System). The loss of SCS results from a common cause failure of SCS or a loss of UHS (Ultimate Heat Sink). One of the postulated common cause failures which lead to the loss of SCS can be a manufacturing deficiency of shutdown cooling pumps, component cooling water pumps or essential service water pumps. The limiting event of the loss of SCS is the loss of UHS since the loss of UHS causes losses of safety systems including SCS, CCWS and ESWS. NO operator action inside the MCR (Main Control Room) during the first 30 minutes and outside the MCR during the first 60 minutes can be credited to recover the failed SCS. The diverse means of the EU-APR1400 for the residual heat removal function with RCS open condition have been developed to comply with the diversity principle of the European design requirements of new nuclear power plants. The results of the preliminary assessment show that the diverse design features are expected to satisfy the design criteria. In the future, more detailed design and assessment for this means will be performed considering interface requirements with completing the design of relevant systems and components

  6. Diverse Design Features of EU-APR1400 for Residual Heat Removal Function with Open RCS

    Energy Technology Data Exchange (ETDEWEB)

    Kweon, Hyeong Do; Lee, Keun Sung; Kim, Yong Soo; Kim, Sung Hwan [Korea Hydro and Nuclear Power Co., Ltd., Daejeon (Korea, Republic of)

    2014-05-15

    Diversity is the fundamental principle in safety system design of new nuclear power plants, which uses different mitigation measures to provide diverse ways of responding to a significant event. Regarding the diversity principle, EU-APR1400 (European APR1400) safety system should be in accordance with European design requirements. This paper provides how the core residual heat can be removed with open RCS (Reactor Coolant System) closure head condition using diverse cooling systems assuming a loss of SCS (Shutdown Cooling System). The loss of SCS results from a common cause failure of SCS or a loss of UHS (Ultimate Heat Sink). One of the postulated common cause failures which lead to the loss of SCS can be a manufacturing deficiency of shutdown cooling pumps, component cooling water pumps or essential service water pumps. The limiting event of the loss of SCS is the loss of UHS since the loss of UHS causes losses of safety systems including SCS, CCWS and ESWS. NO operator action inside the MCR (Main Control Room) during the first 30 minutes and outside the MCR during the first 60 minutes can be credited to recover the failed SCS. The diverse means of the EU-APR1400 for the residual heat removal function with RCS open condition have been developed to comply with the diversity principle of the European design requirements of new nuclear power plants. The results of the preliminary assessment show that the diverse design features are expected to satisfy the design criteria. In the future, more detailed design and assessment for this means will be performed considering interface requirements with completing the design of relevant systems and components.

  7. Application Results MAAP 5.0.2 to Domestic APR1400 Nuclear Power Plant

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Mi Ro; Kim, Hyeong Taek [KHNP-CRI, Daejeon (Korea, Republic of)

    2014-05-15

    There are so many changes in the models such as the Lower head plenum model, Debris Coolability model, Molten Core Concrete Interaction, and the analysis scope is enlarged to the phenomena in the spent fuel pool and the half-loop operation. As a kind of post-Fukushima measures, KHNP is developing the probabilistic safety assessment (PSA) and severe accident management guideline (SAMG) for low power and shutdown (LPSD) mode and MAAP 5.0.2 should be used in these projects as a major analysis program. So, first of all, it is necessary that the parameter file for domestic NPP should be upgraded as current Ver. MAAP4 to Ver. MAAP 5.0.2. KHNP developed the draft version of parameter file for APR1400 type NPP and is being tested for some basic severe accident sequence. In this study, we try to share the information for newly developed parameter and compare the analysis results using MAAP 5.0.2 with previous results using MAAP4. Currently, while developing the LPSD PSA and LPSD SAMG as a kind of post-Fukushima measures, KHNP have the plan in order to upgrade the old parameter file based on MAAP4 to that based on MAAP5.0.2 for all domestic nuclear power plants. As the first effort, we developed the MAAP 5.0.2 parameter file for APR1400 type NPP. In this study, we can find that the newly developed MAAP5.0.2 parameter file for domestic APR1400 type is appropriate for actual analysis. But, as a draft version, it is judged that it should be revised through the sensitivity studies, especially focused on the newly introduced models in MAAP 5.0.2.

  8. Analysis of a 12-Finger Rod Drop using RETRAN/MASTER Code System for APR1400

    International Nuclear Information System (INIS)

    The Optimized Power Reactor 1000 (OPR1000) has 4-finger and 12-finger Control Element Assemblies (CEAs). When the 12-finger CEA is dropped, Core Protection Calculator System (CPCS) shuts down the reactor to prevent fuel damage that could occur from the sudden reactor power peaking. By contrast, the improved CPCS of Advanced Power Reactor 1400 (APR1400), which has systems similar to those of the OPR1000, decreases reactor power rapidly using its Reactor Power Cutback System (RPCS) to avoid unwanted reactor trips caused by the CPCS during a 12- finger CEA drop event. RETRAN is a best-estimate code for transient analysis of Non-LOCA. The RETRAN control logic, which includes the function of reducing reactor power during a 12-Finger CEA drop, has been developed for the APR1400. A MATRAN program has also been developed. MATRAN is the interface program for realtime processing to connect RETRAN with MASTER code which is a nuclear analysis and design code. MATRAN supplies adequate feedback reactivities from the MASTER code to RETRAN code. The purpose of this study is to analyze the behavior of a nuclear reactor core and its primary system using conventional RETRAN analysis procedure and MATRAN program analysis procedure during a 12- finger CEA drop. In addition, the axial power distribution and Axial Shape Index (ASI) are produced by the MATRAN program and they are confirmed as within operation limits

  9. Preliminary Sensitivity Study of Upper Head Nodalization for LBLOCA in APR-1400

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Dong Gu; Yoo, Seung Hun; Cho, Dae-Hyung [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2015-10-15

    In this study, the key-way bypass was determined to be - 0.3 %. The steady state condition which is the initial condition for LBLOCA was obtained by MARS-KS calculation. Up to now, it was assumed that the temperature of the upper dome in APR-1400 was close to that of the cold leg. However, it was found that the temperature of the upper head/dome might be a little lower than or similar to that of the hot leg through the evaluation of the detailed design data. Since the higher upper head temperature affects blowdown quenching and peak cladding temperature in the reflood phase, the nodalization for upper head should be modified. In this study, the preliminary sensitivity study of original and modified nodalization for LBLOCA was performed, and the effect of upper head nodalization and temperature was evaluated qualitatively. In this study, the preliminary sensitivity study of original and modified nodalization for upper head in APR-1400 was performed, and the effect of upper head nodalization and temperature on LBLOCA PCT was evaluated qualitatively. Through the transient calculation, it was confirmed that the upper head temperature affects the water inventory in the upper head at the early stage of LBLOCA so it does the blowdown quenching and following reflood PCT significantly. The results in this study were caused by very conservative upper head temperature determination.

  10. Domestic activity for technical development of the APR1400's RCP performance test

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Seok; Kim, Seok; Bae, Byung-Uhn; Cho, Yun-Jae; Kim, Yeon-Sik; Jeon, Woo-Jin; Yun, Young-Jung [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    The thermal hydraulic and electric capability of the RCP test facility (RCPTF) covers up to 18.5 MPa, 343 .deg. C, 11.7 m{sup 3}/s, and 14.0 MW in the design pressure, temperature, flow rate, and the maximum electric power, respectively. In 2013, commissioning test had been performed to verify its designed capability, followed by several modifications in the RCPTF including signal processing and control logic to enhance verification and evaluation capability of the RCP performance. After finishing the commissioning and modification of the RCPTF, type test for the new-type RCP had been performed successfully. In this paper, several technical issues developed in the 2013 and the type test's method and results will be described. In the present paper, the technical activities for the development of the verification test of APR1400's RCP are described. KAERI has completed the full set of technology development, prerequisite for the RCP verification test, and now on the way to perform a test for the sealing capacity of the seal assembly during the Station Block Out (SBO) condition of APR1400.

  11. Advanced Design Features of APR1400 and Realization in Shin Kori Construction Project

    International Nuclear Information System (INIS)

    APR1400 adopted several advanced design features. To ensure their proper operation as a part of ShinKori 3,4 project, both experimental and analytical work are continuing. In this paper, work on the advanced design features related to enhanced safety is examined. APR1400 safety injection system consists of four independent trains which include four safety injection pump and tanks. A passive flow regulating device called fluidic device is installed in the safety injection tanks. Separate effect tests including a full scale fluidic device tests have been conducted. Integral system tests are in progress. Combination of these work with the analytical work using RELAP5/Mod3 would ensure the proper operation of the new safety injection systems. To mitigate severe accidents, hydrogen mitigation system using PARs and igniters is adopted. Also, active injection system and the streamlined insulation design are adopted to enhance the in-vessel retention capability with the external cooling of RPV strategy. Analytic work with supporting experiments is performed. We are certain that these preparatory work would help the successful adaptation of ADF in ShinKori project. (authors)

  12. Analysis of MSLB for APR1400 using SPACE Mass and Energy Release Methodology

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Seong Min; Ahn, Hyoung Kyoun; Park, Seok Jeong; Park, Chan Eok [KEPCO EnC, Daejeon (Korea, Republic of)

    2015-05-15

    Main Steam Line Break (MSLB) accident is most important Design Basis Accident for containment building functional design. Mass and Energy Release (MER) analysis methodology using Safety and Performance Analysis CodE (SPACE) has been developing. The SPACE which is best estimated code for safety analysis is used to analyze nuclear steam supply system with Containment Analysis Package (CAP). Mass and energy release is predicted for APR1400 during MSLB accident. The peak pressure and temperature are compared with previous MER analysis methodology, KEPCO EnC improved mass and energy release analysis (KIMERA). Various kinds of MSLB for APR1400 are analyzed with MSIV failure and LCC for 102%, 75%, 50%, 20% power. MSLB analysis is performed using linked calculation between SPACE and CAP. As a conclusion, the maximum peak pressure is less conservative than peak pressure by previous methodology. The maximum peak temperature is more conservative than peak temperature by previous methodology. Further work to compare with mass and energy release by previous methodology is needed to establish SPACE MER analysis methodology.

  13. Probability of Neutralization Estimation for APR1400 Physical Protection System Design Effectiveness Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Myungsu; Lim, Heoksoon; Na, Janghwan; Chi, Moongoo [Korea Hydro and Nuclear Power Co. Ltd. Central Research Institute, Daejeon (Korea, Republic of)

    2015-05-15

    It is focusing on development of a new designing process which can be compatible to international standards such as IAEA1 and NRC2 suggest. Evaluation for the design effectiveness was found as one of the areas to improve. If a design doesn't meet a certain level of effectiveness, it should be re-designed accordingly. The effectiveness can be calculated with combination of probability of Interruption and probability of neutralization. System Analysis of Vulnerability to Intrusion (SAVI) has been developed by Sandia National Laboratories for that purpose. With SNL's timely detection methodology, SAVI has been used by U.S. nuclear utilities to meet the NRC requirements for PPS design effectiveness evaluation. For the SAVI calculation, probability of neutralization is a vital input element that must be supplied. This paper describes the elements to consider for neutralization, probability estimation methodology, and the estimation for APR1400 PPS design effectiveness evaluation process. Markov chain and Monte Carlo simulation are often used for simple numerical calculation to estimate P{sub N}. The results from both methods are not always identical even for the same situation. P{sub N} values for APR1400 evaluation were calculated based on Markov chain method and modified to be applicable for guards/adversaries ratio based analysis.

  14. La structure de la population après son lieu de naissance

    Directory of Open Access Journals (Sweden)

    Maria-Magdalena LUPCHIAN

    2008-10-01

    Full Text Available La capacité de polarisation de la ville de Suceava a agrandi d`une manière significative pendant la deuxième moitie de la XXème siècle, grâce au développement de la fonction industrielle de la ville entre 1960 et 1970. L`analyse de la structure de la population après le lieu de naissance a été possible grâceaux données fournies par les recensements de la population de 1930, 1966, 1977, 1992 et 2002(pour toute la ville et grâce aux données fournies par l`enquête réalisée en 2005 sur enéchantillon qui a dépassé 3000 personnes (pour l`analyse au niveau intra urbaine.Dans une première étape, l`aire de provenance de la population de la ville dépassaitles limites du département de Suceava. La ville a consolide son pouvoir d`attraction au niveaudu département et au niveau du Plateau de Suceava après les années `70. Pendant ce période(1950 – 1990, des déplacements très stables se sont développé entre les départements deBotoşani et de Neamţ et le département de Suceava.L`analyse de l`aire de provenance de la population née dans le département deSuceava relève le fait que la ville a représenté et représente encore un pole d`attraction pour lamoitie de plateau du département de Suceava. La ville chef lieu de département est enconcurrence avec les villes plus petites mais viables (Rădăuţi, Fălticeni, situées en proximité.L`analyse de la structure de la population après son lieu de naissance au niveau intraurbaine démontre l`opposition qui existe entre les vieux quartiers d`habitat individuel (ou lapopulation née en ville est majoritaire et les nouveaux quartiers, d`habitat collectif, édifiésdans les années d`industrialisation de la ville – Burdujeni, George Enescu – où le pourcentagede ceux nes dans le milieu rural est maximal.On remarque aussi la position intermédiaire du quartier Centre et des quartierspéricentraux, mais aussi du nouveau quartier Obcine, avec des pourcentage sur la

  15. Après-Coup in French Psychoanalysis: The Long Afterlife of Nachträglichkeit: The First Hundred Years, 1893 to 1993.

    Science.gov (United States)

    House, Jonathan; Slotnick, Julie

    2015-10-01

    Après-coup finds its origins in Freud's earliest psychoanalytic writings, but it was only half a century ago that French psychoanalysts rediscovered, clarified, and developed the concept and so brought it recognition as an essential Freudian concept. Because the history of après-coup is embedded in the French reading of Freud, this article will give an account of that reading in relation to après-coup.

  16. Après-Coup in French Psychoanalysis: The Long Afterlife of Nachträglichkeit: The First Hundred Years, 1893 to 1993.

    Science.gov (United States)

    House, Jonathan; Slotnick, Julie

    2015-10-01

    Après-coup finds its origins in Freud's earliest psychoanalytic writings, but it was only half a century ago that French psychoanalysts rediscovered, clarified, and developed the concept and so brought it recognition as an essential Freudian concept. Because the history of après-coup is embedded in the French reading of Freud, this article will give an account of that reading in relation to après-coup. PMID:26485487

  17. Thermal-hydraulic evaluation of passive containment cooling system of improved APR+ during LOCAs

    Energy Technology Data Exchange (ETDEWEB)

    Jeon, Byong Guk; NO, Hee Cheon, E-mail: hcno@kaist.ac.kr

    2014-10-15

    Highlights: • Larger air holdup tanks are confirmed to be needed for PCCS through MARS simulation. • Condensation model in MARS gives lower heat transfer than Dehbi's correlation. • Heat transfer resistance of steam–air mixture is dominant for PCCS tubes. • Heat sink structures remove dominant amount of decay heat initially. • Flow instability is eased at higher tube inlet form loss, return level, and angle. - Abstract: Various reactor concepts and technologies have been devised and evaluated to ensure the integrity of the core and the containment under a prolonged station blackout. After the successful validation of the passive auxiliary feedwater system (PAFS) of Advanced Power Reactor Plus (APR+), Korea is considering an improved APR+ with a passive containment cooling system (PCCS). In a previous paper, we suggested a PCCS design based on APR+ and performed a scoping analysis. We performed a MARS simulation for the thermal hydraulic evaluation of the system behavior, including natural circulation through the Passive Condensation Cooling Tank (PCCT) water pool and inside PCCS tubes as well as steam–air mixture condensation inside the containment. Through a simulation using the MARS system code, we investigated the effect of air holdup tanks (AHTs) on reduction of the air fraction in the containment, the effects of several steam–air mixture condensation models, the role of heat structures, and the flow instability inside the PCCS tubes. We found that the presence of AHT reduced the number of required PCCS tubes by more than half and the heat resistance of the steam–air mixture side is dominant in terms of governing the overall performance of PCCS. The embedded MARS condensation model and Uchida's correlation gave lower heat transfer coefficients than Dehbi's correlation, and heat structures removed more decay heat than PCCS tubes. Finally, intense flow instability inside the PCCS tubes was observed and was mitigated by placing

  18. Le Chaebol après la crise financière de 1997

    Directory of Open Access Journals (Sweden)

    Chung-Yeol Park

    2008-11-01

    Full Text Available L’objet de cet article est de présenter les mutations subies par les Chaebols à la suite de la crise financière de 1997. La première section est consacrée à un bref rappel de la formation et du développement des Chaebols, ainsi qu’à une caractérisation des attributs de leur forme organisationnelle. Il s’agit ainsi d’indiquer la « forme  canonique » que revêtait le Chaebol avant la crise, afin de fixer des repères pour mesurer et évaluer l’ampleur et la nature des mutations intervenues après la crise de 1997. La deuxième et la troisième section proposent une analyse de la réforme financière et de la réforme du secteur des entreprises conduites en Corée après 1997 et largement influencées par le FMI. La quatrième section présente une analyse concrète des changements au sein de deux Chaebols majeurs (Hyundai et Samsung depuis la crise financière. A partir de ces études de cas et de données empiriques complémentaires sont mis en évidence tout à la fois les changements et la permanence dans la structure et le comportement des Chaebols, suite aux modifications institutionnelles introduites après la crise financière de 1997.The Chaebol after the 1997. Financial Crisis Changes and Continuity. The paper presents the changes undergone by the Korean Chaebols after the financial crisis of 1997. The first section shortly recalls the history of the birth and development of the Chaebols and presents their specific organizational traits.  The second and third sections are dedicated to the presentation of the financial reforms and of the reforms of the enterprises implemented in Korea after 1997. The fourth section presents two cases studies of the changes introduced after 1997 on two major chaebols : Hyundai Group and Samsung Group. These case studies and other more general empirical data are used to evaluate both the changes and the continuity in Chaebol’s organizational forms and behaviours after the 1997

  19. Signoles Aude, Le Hamas au pouvoir et après ?, Toulouse, Editions Milan, 2006.

    Directory of Open Access Journals (Sweden)

    Jean-François Legrain

    2007-11-01

    Full Text Available Dans les étroites limites imposées par la collection (absence totale de notes et de bibliographie, 112 p. en format réduit, le petit livre d’Aude Signoles, Le Hamas au pouvoir et après ?, commence à combler un vide de l’édition française. Le seul livre jusque là disponible en français et entièrement consacré à Hamas remonte à 7 années maintenant ; doté de nombreuses erreurs factuelles et faisant comme si Hamas était apparu avec l’autonomie des années 1990, il ignorait tout de son passé d’Ass...

  20. Reliability analysis of protection system of advanced pressurized water reactor - APR 1400

    International Nuclear Information System (INIS)

    Reliability analysis was carried out for the protection system of the Korean Advanced Pressurized Water Reactor - APR 1400. The main focus of this study was the reliability analysis of digital protection system, however, towards giving an integrated statement of complete protection reliability an attempt has been made to include the shutdown devices and other related aspects based on the information available to date. The sensitivity analysis has been carried out for the critical components / functions in the system. Other aspects like importance analysis and human error reliability for the critical human actions form part of this work. The framework provided by this study and the results obtained shows that this analysis has potential to be utilized as part of risk informed approach for future design / regulatory applications

  1. Development and Verification of MAAP5.0.3 Parameter file for APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Mi Ro; Kim, Hyeong Taek [KHNP-CRI, Daejeon (Korea, Republic of)

    2015-05-15

    After the Fukushima accident, EPRI has continuously upgrade the MAAP5 (Modular Accident Analysis Program version 5) that is expected to expand the limitation of MAAP4. As a result of those efforts, the MAAP5.0.2 (Build 5020000) was released officially in December, 2013. Also, in August, 2014, the newest version of MAAP5, MAAP 5.0.3 (Build 5030000), was officially released. The parameter file development is essential for severe accident analysis using MAAP code for specific plant. In 2014, KHNP developed the first draft version of MAAP 5.0.2 parameter file for APR1400 type NPP and had tested for some basic severe accident sequence. And, until now, KHNP has continuously complemented the first draft version of APR1400 type NPP parameter file for MAAP 5.0.2 and 5.0.3. In this study, we analysis the MCCI phenomena using MAAP 5.0.3 version with the 2''n''d draft version of APR1400 parameter file developed by KHNP. The purpose of this study is to compare the major difference in MAAP 5.0.2 and 5.0.3 MCCI model and to verify the appropriateness of the 2''n''d draft version of parameter file. The MCCI phenomena have been controversial issues in the severe accident progression, so there have been great efforts to solve them until now. As the part of these efforts, EPRI published MAAP 5.0.3 version which is known that the 'Lower head plenum model' and the 'MCCI model' was upgraded. KHNP have the plan in order to upgrade the old parameter file based on MAAP4 to that based on MAAP5.0.2 or higher version for all domestic nuclear power plants. So, we have continuously developed the MAAP 5.0.2 and 5.0.3 parameter file for APR1400 type NPP. In this study, we analyzed the MCCI phenomena using MAAP 5.0.3 and 2''n''d draft version parameter file. And we found some insight as belows; (1) The Melt Eruption Model can greatly affect the MCCI progression only in the case of limestone concrete in the wet cavity

  2. Preliminary Analysis of Ex-Vessel Steam Explosion using TEXAS-V code for APR1400

    International Nuclear Information System (INIS)

    The purpose of this study is to explore input development and the audit calculation using TEXAS-V code for ex-vessel steam explosion for a flooded reactor cavity of APR1400. TEXAS computational models are one of the simplified tools for simulations of fuel-coolant interaction during mixing, triggering and explosion phase. The models of TEXAS code were validated by performing the fundamental experimental investigation in the KROTOS facility at JRC, Ispra. The experiments such as KROTOS and FARO experiment are aimed at providing benchmark data to examine the effect of fuel-coolant initial conditions and mixing on explosion energetics with alumina and prototypical core material. TEXAS-V code used in this study was to analyze and predict the ex-vessel steam explosion for a reactor scale. The input deck to simulate the flooded reactor cavity of APR1400 is developed and base case calculation is performed. This study will provide a base for further study. The code will be of use for the evaluation and sensitivity study of ex-vessel steam explosion for ERVC strategy in the future studies. Analysis result of this study is similar to the result of other study. Through this study, it is found that TEXAS-V could be the used as a tool for predicting the steam explosion load on a reactor scale, as fast running computer code. In addition, TEXAS-V code could be to evaluate the impact of various uncertainties, which are not clearly understood yet, to provide a conservative envelope for the steam explosion

  3. Evaluation of the In-vessel Downstream Effects for the APR1400 Design and License

    Energy Technology Data Exchange (ETDEWEB)

    Suh, Jeong-kwan; Kim, Jae-won; Kwon, Sun-guk; Lee, Jae-yong [KHNP Central Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    These reports include the licensing issues as follows; the effect of a flow channel gap change, the effect of debris settling, the accuracy of the GF630 flow meter, the effect of bubbles impinging on the bottom nozzle, and the bypass fiber amount. In this paper, the valuation results of the in-vessel downstream effects for the APR1400 were described. In addition, the effect of a flow channel gap change and the bypass fiber amount were evaluated. In-vessel downstream effect tests with a mock-up PLUS7 fuel assembly were performed to confirm that the head losses caused by debris meet the available driving head following a LOCA. All the test results showed lower pressure drops than the available head limits. Therefore, a sufficient driving force is available to maintain an adequate flow rate, and the LTCC capability is adequately maintained in the APR1400. A sensitivity test was conducted to assess the effect of a change in the gap size between the mock-up fuel assembly and the test column. The maximum pressure drop recorded for the test was 19.73 kPa under the re-manufactured condition. This value is larger by 1.6% than the previous test result (19.4 kPa) under the same conditions. As such, changing the gap of the flow path between the mock-up fuel assembly and the test column from the previous manufactured conditions to the re-manufactured conditions is expected to result in a slight increase in the differential pressure. However, this is a negligible amount compared to the test uncertainty value of 25%.

  4. New tools for NTD vaccines: A case study of quality control assays for product development of the human hookworm vaccine Na-APR-1M74.

    Science.gov (United States)

    Pearson, Mark S; Jariwala, Amar R; Abbenante, Giovanni; Plieskatt, Jordan; Wilson, David; Bottazzi, Maria Elena; Hotez, Peter J; Keegan, Brian; Bethony, Jeffrey M; Loukas, Alex

    2015-01-01

    Na-APR-1(M74) is an aspartic protease that is rendered enzymatically inactive by site-directed mutagenesis and is a candidate antigen component in the Human Hookworm Vaccine. The mutant protease exerts vaccine efficacy by inducing antibodies that neutralize the enzymatic activity of wild type enzyme (Na-APR-1wt) in the gut of the hookworm, thereby depriving the worm of its ability to digest its blood meal. Previously, canines immunized with Na-APR-1(M74) and challenged with Ancylostoma caninum were partially protected against hookworm challenge infection, especially from the loss in hemoglobin observed in control canines and canine immunoglobulin (Ig) G raised against Na-APR-1 was shown to inhibit the enzymatic activity of Na-APR-1 wt in vitro, thereby providing proof of concept of Na-APR-1(M74) as a vaccine antigen. The mutated version, Na-APR-1(M74), was then expressed at the cGMP level using a Nicotiana benthamiana expression system (Fraunhofer, CMB, Delaware, MD), formulated with Alhydrogel®, and used to immunize mice in a dose-ranging study to explore the enzyme-neutralizing capacity of the resulting anti- Na-APR-1(M74) IgG. As little as 0.99 μg of recombinant Na-APR-1(M74) could induce anti Na-APR-1(M74) IgG in mice that were capable of inhibiting Na-APR-1w t-mediated digestion of a peptide substrate by 89%. In the absence of enzymatic activity of Na-APR-1(M74) as a surrogate marker of protein functionality, we developed an assay based on the binding of a quenched fluorescence-labeled inhibitor of aspartic proteases, BODIPY-FL pepstatin A (BDP). Binding of BDP in the active site of Na-APR-1 wt was demonstrated by inhibition of enzymatic activity, and competitive binding with unlabelled pepstatin A. BDP also bound to Na-APR-1(M74) which was assessed by fluorescence polarization, but with an ∼ 50-fold reduction in the dissociation constant. Taken together, these assays comprise a "toolbox" that could be useful for the analyses of Na-APR-1(M74) as it

  5. New tools for NTD vaccines: A case study of quality control assays for product development of the human hookworm vaccine Na-APR-1M74.

    Science.gov (United States)

    Pearson, Mark S; Jariwala, Amar R; Abbenante, Giovanni; Plieskatt, Jordan; Wilson, David; Bottazzi, Maria Elena; Hotez, Peter J; Keegan, Brian; Bethony, Jeffrey M; Loukas, Alex

    2015-01-01

    Na-APR-1(M74) is an aspartic protease that is rendered enzymatically inactive by site-directed mutagenesis and is a candidate antigen component in the Human Hookworm Vaccine. The mutant protease exerts vaccine efficacy by inducing antibodies that neutralize the enzymatic activity of wild type enzyme (Na-APR-1wt) in the gut of the hookworm, thereby depriving the worm of its ability to digest its blood meal. Previously, canines immunized with Na-APR-1(M74) and challenged with Ancylostoma caninum were partially protected against hookworm challenge infection, especially from the loss in hemoglobin observed in control canines and canine immunoglobulin (Ig) G raised against Na-APR-1 was shown to inhibit the enzymatic activity of Na-APR-1 wt in vitro, thereby providing proof of concept of Na-APR-1(M74) as a vaccine antigen. The mutated version, Na-APR-1(M74), was then expressed at the cGMP level using a Nicotiana benthamiana expression system (Fraunhofer, CMB, Delaware, MD), formulated with Alhydrogel®, and used to immunize mice in a dose-ranging study to explore the enzyme-neutralizing capacity of the resulting anti- Na-APR-1(M74) IgG. As little as 0.99 μg of recombinant Na-APR-1(M74) could induce anti Na-APR-1(M74) IgG in mice that were capable of inhibiting Na-APR-1w t-mediated digestion of a peptide substrate by 89%. In the absence of enzymatic activity of Na-APR-1(M74) as a surrogate marker of protein functionality, we developed an assay based on the binding of a quenched fluorescence-labeled inhibitor of aspartic proteases, BODIPY-FL pepstatin A (BDP). Binding of BDP in the active site of Na-APR-1 wt was demonstrated by inhibition of enzymatic activity, and competitive binding with unlabelled pepstatin A. BDP also bound to Na-APR-1(M74) which was assessed by fluorescence polarization, but with an ∼ 50-fold reduction in the dissociation constant. Taken together, these assays comprise a "toolbox" that could be useful for the analyses of Na-APR-1(M74) as it

  6. Homology modeling of dissimilatory APS reductases (AprBA of sulfur-oxidizing and sulfate-reducing prokaryotes.

    Directory of Open Access Journals (Sweden)

    Birte Meyer

    Full Text Available BACKGROUND: The dissimilatory adenosine-5'-phosphosulfate (APS reductase (cofactors flavin adenine dinucleotide, FAD, and two [4Fe-4S] centers catalyzes the transformation of APS to sulfite and AMP in sulfate-reducing prokaryotes (SRP; in sulfur-oxidizing bacteria (SOB it has been suggested to operate in the reverse direction. Recently, the three-dimensional structure of the Archaeoglobus fulgidus enzyme has been determined in different catalytically relevant states providing insights into its reaction cycle. METHODOLOGY/PRINCIPAL FINDINGS: Full-length AprBA sequences from 20 phylogenetically distinct SRP and SOB species were used for homology modeling. In general, the average accuracy of the calculated models was sufficiently good to allow a structural and functional comparison between the beta- and alpha-subunit structures (78.8-99.3% and 89.5-96.8% of the AprB and AprA main chain atoms, respectively, had root mean square deviations below 1 A with respect to the template structures. Besides their overall conformity, the SRP- and SOB-derived models revealed the existence of individual adaptations at the electron-transferring AprB protein surface presumably resulting from docking to different electron donor/acceptor proteins. These structural alterations correlated with the protein phylogeny (three major phylogenetic lineages: (1 SRP including LGT-affected Archaeoglobi and SOB of Apr lineage II, (2 crenarchaeal SRP Caldivirga and Pyrobaculum, and (3 SOB of the distinct Apr lineage I and the presence of potential APS reductase-interacting redox complexes. The almost identical protein matrices surrounding both [4Fe-4S] clusters, the FAD cofactor, the active site channel and center within the AprB/A models of SRP and SOB point to a highly similar catalytic process of APS reduction/sulfite oxidation independent of the metabolism type the APS reductase is involved in and the species it has been originated from. CONCLUSIONS: Based on the comparative

  7. Oximetry alone versus portable polygraphy for sleep apnea screening before bariatric surger

    OpenAIRE

    Malbois M.

    2010-01-01

    Rapport de SynthèseIntroductionLa recherche des apnées du sommeil est recommandée dans la prise en charge préopératoire des patients obèses chez qui une chirurgie bariatrique est envisagée. Toutefois le type d'examen nécessaire pour la détection des apnées dans cette population reste encore discuté. L'objectif de cette étude était de comparer la sensibilité de l'oxymétrie par rapport à la polygraphie lors du screening préopératoire de l'apnée obstructive du sommeil.MéthodeNous avons analysé r...

  8. Apreçamento de opções de IDI usando o modelo CIR

    Directory of Open Access Journals (Sweden)

    José Santiago Fajardo Barbachan

    2003-06-01

    Full Text Available A opção de IDI da BM&F possui características peculiares que torna o seu apreçamento diferente das opções de taxa de juros mais comuns, como as de títulos de renda fixa. Este artigo desenvolve uma fórmula para apreçamento dessas opções de IDI, utilizando a precificação livre de arbitragem. O modelo utilizado considera apenas um fator estocástico: a taxa de juros livre de risco de curto prazo. A equação diferencial usada para modelar o comportamento da taxa de juros é a do modelo CIR (COX INGERSOLL & ROSS, 1985, que possui reversão à média e não permite a existência de taxas de juros nominais negativas. Também é feita uma estimação dos parâmetros do modelo proposto baseando-se em dados históricos, para então comparar o preço teórico da opção baseado nestes parâmetros com os preços de mercado e com o preço teórico considerando a modelagem de Vasicek (1977.The IDI option from the BM&F (Commodities and Futures Exchange has unusual characteristics, that make its pricing different from common interest rate options. This paper develops a closed form formula for the pricing of these IDI options, using an arbitrage-free pricing approach. The model used considers only one stochastic factor: the short-term risk-free interest rate. The differential equation used to model the behavior of the interest rate comes from the CIR (COX INGERSOLL & ROSS, 1985 model, which has mean reversion property and does not allow negative nominal interest rates. It is also done a parameter estimation of the proposed model based on historic data, and then compares the theoretical price of the option based on these parameters with the market price and with the theoretical price considering the Vasicek (1977 model.

  9. Numerical Analysis of Overpressure Transient during Cold Shutdown Operation for APR1400 Nuclear Power Plant

    International Nuclear Information System (INIS)

    ASME code describes specified requirements as allowable pressure for materials of RCPB for low temperature condition. RCPB should be protected during the condition as well because, if it fails, radioactive material can be released. ASME section III appendix G stipulates that maximum allowable pressure of reactor coolant system is 20% of hydrostatic test pressure which means the maximum allowable pressure below lowest service temperature. Generally we determine most severe mass-addition or energy-addition transients arisen by operator errors, malfunction of components or other causes for initiating events of LTOP (low temperature overpressure protection) analysis. According to safety analysis report for APR1400, most severe transient for mass addition begins from startup of one charging pump and four high pressure safety injection (HPSI) pumps at the same time and, on the other hand, most severe transient for energy addition begins from startup of one reactor coolant pump and, as a results of it, heat transfer from secondary side of SG filled with higher temperature water to primary side of SG. If RCS pressure increases and reaches a set pressure of LTOP relief valves, installed on suction pipe of shutdown cooling system (SCS), the valves perform the function of RCPB protection during cold shutdown status. PR1400 for overpressure transient under cold shutdown status. From the results of analysis of mass addition and energy addition, maximum RCS pressure is maintained lower than maximum allowable pressure for LTOP required in ASME code

  10. Numerical study on thermal stratification phenomenon in SCS branch pipe for APR1400

    International Nuclear Information System (INIS)

    The thermal stratification in the unisolable branch pipe for the Shutdown Cooling System (SCS) suction line for APR1400 has been studied. The vertical-horizontal branch pipe with an isolation valve at the end, and under Reactor System (RCS) operating condition is susceptible to the thermal stratification due to the stagnation flow around the isolation valve. The formation of the thermal stratification at the horizontal part of the branch line should be evaluated to determine the design consideration of thermal fatigue. Three dimensional transient analysis for the thermal stratification in a branch pipe is performed using the computational fluid dynamics code, FLUENT, to evaluate the velocity and temperature distribution. Parametric studies have been carried out to investigate the effect of the design and operating conditions. Parameters like the hot leg flow velocity, the outleakage through the isolation valve and the thermal insulation on piping wall are taken account. The analyses show that the temperature difference caused by the thermal stratification at the horizontal part of the unisolable branch pipe is not remarkable under normal operating conditions since the turbulent penetration length is developed deeply in the branch pipe due to the high velocity flow in the RCS hot leg. (author)

  11. A study on the mitigating capability of an auxiliary feedwater system during SBO for APR1400

    International Nuclear Information System (INIS)

    The objective of this paper is to establish an auxiliary feedwater (AFW) operational technical bases for the Korean Next Generation Reactor (APR1400) by modeling the plant, and by analyzing station blackout (SBO) using the MELCOR code. For the integrity of the reactor vessel and containment safety against severe accidents, it is essential to understand the severe accident sequences and to assess accident progression accurately using computer codes. Furthermore, it is important to attain the capability to analyze the advanced nuclear reactor design for the severe accident prevention and mitigation. Accident analyses are also undertaken to find out how effective AFW is mitigating in severe accident progresses. A nominal base case for SBO without AFW, time interval between feedwater stop and reactor vessel failure is 12,740 seconds. When AFW operates to mitigate the SBO accident progression 2, 4 and 8 hours after SBO starts, the reactor vessel failure is delayed for 20,415 seconds, 22,633 seconds and 26,508 seconds, respectively thus the operator has more time available for AC recovery and accident mitigation to prevent reactor vessel failure. (author)

  12. Numerical Analysis of Overpressure Transient during Cold Shutdown Operation for APR1400 Nuclear Power Plant

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Byung Soo; Kim, Yun Il; Jung, Ae Ju; Min, Bok Ki [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2015-05-15

    ASME code describes specified requirements as allowable pressure for materials of RCPB for low temperature condition. RCPB should be protected during the condition as well because, if it fails, radioactive material can be released. ASME section III appendix G stipulates that maximum allowable pressure of reactor coolant system is 20% of hydrostatic test pressure which means the maximum allowable pressure below lowest service temperature. Generally we determine most severe mass-addition or energy-addition transients arisen by operator errors, malfunction of components or other causes for initiating events of LTOP (low temperature overpressure protection) analysis. According to safety analysis report for APR1400, most severe transient for mass addition begins from startup of one charging pump and four high pressure safety injection (HPSI) pumps at the same time and, on the other hand, most severe transient for energy addition begins from startup of one reactor coolant pump and, as a results of it, heat transfer from secondary side of SG filled with higher temperature water to primary side of SG. If RCS pressure increases and reaches a set pressure of LTOP relief valves, installed on suction pipe of shutdown cooling system (SCS), the valves perform the function of RCPB protection during cold shutdown status. PR1400 for overpressure transient under cold shutdown status. From the results of analysis of mass addition and energy addition, maximum RCS pressure is maintained lower than maximum allowable pressure for LTOP required in ASME code.

  13. General relativistic magnetohydrodynamic simulations of binary neutron star mergers with the APR4 equation of state

    Science.gov (United States)

    Endrizzi, A.; Ciolfi, R.; Giacomazzo, B.; Kastaun, W.; Kawamura, T.

    2016-08-01

    We present new results of fully general relativistic magnetohydrodynamic simulations of binary neutron star (BNS) mergers performed with the Whisky code. All the models use a piecewise polytropic approximation of the APR4 equation of state for cold matter, together with a ‘hybrid’ part to incorporate thermal effects during the evolution. We consider both equal and unequal-mass models, with total masses such that either a supramassive NS or a black hole is formed after merger. Each model is evolved with and without a magnetic field initially confined to the stellar interior. We present the different gravitational wave (GW) signals as well as a detailed description of the matter dynamics (magnetic field evolution, ejected mass, post-merger remnant/disk properties). Our simulations provide new insights into BNS mergers, the associated GW emission and the possible connection with the engine of short gamma-ray bursts (both in the ‘standard’ and in the ‘time-reversal’ scenarios) and other electromagnetic counterparts.

  14. General Relativistic Magnetohydrodynamic Simulations of Binary Neutron Star Mergers with the APR4 Equation of State

    CERN Document Server

    Endrizzi, Andrea; Giacomazzo, Bruno; Kastaun, Wolfgang; Kawamura, Takumu

    2016-01-01

    We present new results of fully general relativistic magnetohydrodynamic (GRMHD) simulations of binary neutron star (BNS) mergers performed with the Whisky code. All the models use a piecewise polytropic approximation of the APR4 equation of state (EOS) for cold matter, together with a "hybrid" part to incorporate thermal effects during the evolution. We consider both equal and unequal-mass models, with total masses such that either a supramassive NS or a black hole (BH) is formed after merger. Each model is evolved with and without a magnetic field initially confined to the stellar interior. We present the different gravitational wave (GW) signals as well as a detailed description of the matter dynamics (magnetic field evolution, ejected mass, post-merger remnant/disk properties). Our simulations provide new insights into BNS mergers, the associated GW emission and the possible connection with the engine of short gamma-ray bursts (both in the "standard" and in the "time-reversal" scenarios) and other electro...

  15. Preliminary COM3D Analysis for H{sub 2} Combustion in the APR1400 Containment

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Hyung Seok; Kim, Jongtae; Kim, Sang-Baik; Hong, Seong-Wan [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    In order to assure the containment integrity of APR1400, it is necessary to evaluate an overpressure buildup resulting from a propagation of hydrogen flame along the structure and wall in the containment during a severe accident using the COM3D. Korea Atomic Energy Research Institute (KAERI) established a numerical analysis system for evaluating an overpressure buildup owing to a hydrogen combustion in the containment of a nuclear power plant by importing COM3D from KIT in Germany. The COM3D has been currently used in the simulations of the combustions and explosions, together with the system of industrial risk mitigation of hydrogen and burnable gases in nuclear containment and auxiliary buildings. KAERI performed the hydrogen combustion analysis using the COM3D code with the initial hydrogen distribution calculated by the GASFLOW under assumption of 85% metal-water reaction in the reactor vessel. From the COM3D results, we can know that the pressure buildup was about 100 kPa because the flame speed was not increased above 1000 m/s and the pressure wave passed through the open spaces in the large containment.

  16. Sub compartment pressurization analysis for auxiliary building of APR1400DC

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Moon Oh; Lee, Hee Do [Atomic Creative Technology, Daejeon (Korea, Republic of)

    2012-10-15

    Generally, the sub compartment of PWR means a fully or partially enclosed volume that could house high-energy piping systems or restrict the flow of fluid in the event of a postulated pipe rupture. To meet the requirements of General Design Criteria (GDC) 4 and 50, Standard Review Plan (SRP) 6.2.1.2 states that the sub compartments shall be designed with sufficient margin to prevent the fracture of structure due to pressure differential across the walls of the sub- compartment and specifies the criteria related to the design and functional sub compartment nodalization schemes, vent flow path and vent flow behavior. Therefore the sub compartments structures within the containment and auxiliary building are designed to withstand the transient differential pressures loads, jet impingement forces, and pipe whip forces occurring due to a postulated pipe break. In this paper, the analyses of pressure transients after a postulated pipe rupture in sub compartments of APR1400DC auxiliary building is performed and the calculated peak differential pressures during the piping break transients for each sub compartment are less than structural design differential pressures.

  17. Numerical study of fluidic device in APR1400 using free surface model

    International Nuclear Information System (INIS)

    A fluidic device (FD) has been adopted in the safety injection tanks (SITs) of APR1400. A flow control mechanism of the FD was used to vary the flow regime in the vortex chamber corresponding to the SITs water level. The flow regime in the vortex chamber has a different pressure loss from low to high in accordance with the SITs water level. Nitrogen at the top of the SIT could be released owing to inertia of discharge flow when changing from a high flow rate to a low flow rate. This phenomenon is important to design improvement perspective because it can affect the performance of the FD. This paper shows a result of a preliminary numerical study to obtain the transient data related to air release in the flow turn down period using a two fluid free surface model provided from ANSYS CFX 13.0. In conclusion, there is no significant effect on the performance of the FD, though a small quantity of air is released during the flow turn down period

  18. Sensitivity Analysis of Ex-Vessel Steam Explosion usion TEXAS-V code for APR1400

    International Nuclear Information System (INIS)

    This study conducted the influence of melt velocity and melt diameter on the steam explosion calculation. There was strong influence of the jet diameter and velocity on the explosion. If there is the maximum pressure at the walls, the steam explosion loads can be too high to resist on the cavity wall. In the future study, TEXAS-V code will be used to evaluate the impact of various uncertainties to provide a conservative envelope for the steam explosion. In severe accidents, the corium can come into contact with coolant either when it flows to the bottom of the reactor vessel and encounters the reactor coolant, or when it breaches the reactor vessel and flows into the reactor containment. A steam explosion could then weaken the containment structures, such as the reactor vessel or the concrete walls of the containment building. The purpose of this study is to calculate using TEXAS-V code for ex-vessel steam explosion for a flooded reactor cavity of APR1400. TEXAS-V code to analyze and predict the ex-vessel steam explosion for a reactor scale is used

  19. Ārsta un farmaceita sadarbība pacientu aprūpē

    OpenAIRE

    Tione, Zane

    2016-01-01

    Sakārtota un pieejama veselības aprūpes sistēma valstī, var ievērojami uzlabot dzīves kvalitāti un nodrošināt valsts izaugsmi un konkurētspēju. Tomēr, kā zināms, svarīgs nosacījums šajā procesā ir arī pašu sistēmas dalībnieku iniciatīvai, viņu izrādītā vēlme uz sadarbību, vienotu mērķu sasniegšanai. Aktuāli ir noskaidrot kāda ir šī brīža situācija valstī, vai ārstiem un farmaceitiem ir vēlme šo komunikāciju uzlabot. Bakalaura darba mērķis ir noskaidrot vai pastāv ārstu un farmaceitu sadarbīb...

  20. Thermal-hydraulic evaluation of passive containment cooling system of improved APR+ during LOCAs

    Energy Technology Data Exchange (ETDEWEB)

    Jeon, Byong Guk; No, Hee Cheon [Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of)

    2014-05-15

    In performance of Passive Containment Cooling System (PCCS), sound operation of PCCS heat exchanger (HX) tubes is vital. To clarify their heat transfer function, various experiments are in progress, involving our group. Furthermore, in case of externally condensed HXs, careful evaluation of flow instability inside HX tubes are of prime importance. In PANDA integral tests targeting HXs of KERENA, a huge oscillation of flow inside tubes is observed. Flow instability is attributed to various reasons and classified into two types: static instability (ex. Ledinegg instability) and dynamic instability (ex. density wave oscillation). The former one is related to multiple stable flow rates at a given pressure drop under equilibrium condition while the latter one involves propagation time and feedback phenomena in transient condition. PCCS tubes correspond to the second type, dynamic instability. The detailed explanations are well documented. Our group suggested a PCCS design featuring an air holdup tank (AHT) for removing air near heat exchangers. Based on the design, the thermal hydraulic characteristics of PCCS are explored in this paper. Thermal hydraulic assessment of proposed PCCS is performed using a system code, MARS. Based on APR+, the required number of PCCS HX tubes are calculated with respect to AHT volume. We confirmed that larger AHT is preferred. Flow instability inside PCCS HX tubes are observed. Through sensitivity study, larger inlet orifice plate, return nozzle height, and tube angle are found to be most effective in stabilizing the flow.

  1. Martin Luther King, 40 ans après sa disparition

    Directory of Open Access Journals (Sweden)

    Hélène Harter

    2009-01-01

    Full Text Available Le 4 avril 1968 Martin Luther King est assassiné à Memphis. Moins de cinq ans après la mort du président Kennedy, les Etats-Unis sont à nouveau touchés par la violence politique. Cet article retrace le parcours qui a conduit le révérend King jusqu’à Memphis en cette année politiquement et socialement agitée. Comment sa mort est-elle vécue aux États-Unis ? Quelle mémoire conserve-t-on de lui aujourd’hui ?On April 4, 1968 Martin Luther King was assassinated in Memphis. Less than five years after the death of President Kennedy, the United States were affected again by political violence. This article explains why Rev. King went to Memphis during this politically and socially troubled year. How his death has been perceived in the United States? Does his legacy still live on forty years after his death?

  2. Single port-assisted fully laparoscopic abdominoperineal resection (APR) with immediate V-RAM flap reconstruction of the perineal defect.

    LENUS (Irish Health Repository)

    Ali, Sayid

    2012-09-01

    Abdominoperineal resection (APR) of anorectal cancers after neoadjuvant chemoradiotherapy may incur significant perineal morbidity. While vertical rectus abdominis muscle (V-RAM) flaps can fill the pelvic resection space with health tissue, their use has previously been described predominantly in association with laparotomy. Here, we describe a means of combination laparoscopic APR with V-RAM flap reconstruction that allows structural preservation of the entire abdominal wall throughout the oncological resection and of the deep parietal layers after V-RAM donation. Furthermore, a single port access device used at the end colostomy site allows a second senior surgeon assist with an additional two working instruments for the purpose of improved pelvic tissue retraction, especially useful in obese patients.

  3. Scoping Test on the Effects of Boron and Buffer in the Mockup PLUS7 Fuel Assembly of the APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Suh, Jeong Kwan; Kwon, Sun Guk; Kim, Jae Won; Lee, Jae Yong [KHNP Central Research Institute, Daejeon (Korea, Republic of)

    2013-10-15

    Test results of the repeatability and the boron/buffer effects are presented, and compared with the acceptance basis for the LTCC of the APR1400. To address GSI-191 of the APR1400, we have performed a series of FA tests using a mockup PLUS7. The test results of repeatability performed at limiting conditions meet the acceptance basis compared with the reference results (SK34-61∼64) within 7% difference. Boron and buffer in the fluid lowered pressure drop across the entire FA compared with the condition without them. The test results of boron and buffer effects meet the acceptance head loss (91.8 kPa) of the APR1400 with a sufficient margin. To address U. S. Nuclear Regulatory Commission (NRC) Generic Safety Issue (GSI)-191, we have performed a series of fuel assembly (FA) head loss tests. The goal of this test is to confirm that there is sufficient available head when the debris reaches the core inlets of the APR1400 during a loss-of-coolant accident (LOCA), and that the long-term core cooling (LTCC) is not impeded. To move forward with the resolution of GSI-191 in-vessel effects, we have performed a scoping test on the effects of boron and buffer at ambient temperature. In test SK34-205, repeatability of the tests was confirmed at the limiting conditions. In a scoping test SK34-245, boron and Tri-Sodium Phosphate (TSP) buffer were added prior to the debris addition.

  4. Analysis of Hydrogen Risk Mitigation System for Severe Accidents of EU-APR1400 Using MAAP4 code

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Mun Soo; Suh, Jung Soo; Bae, Byoung Hwan [KHNP Central Research Institute, Daejeon (Korea, Republic of)

    2011-10-15

    According to the EUR (European Utility Requirements for LWR Nuclear Power Plants), it is mandatory that the HMS (Hydrogen Mitigation System) of the Eu-APR1400 should be equipped with a passive or automatic hydrogen control system. Considering this requirement, a PAR (Passive Autocatalytic Recombiner) system was adopted for the HMS of the Eu-APR1400. This passive HMS should be evaluated carefully in order to ensure that the HMS has adequate capacity to control hydrogen concentrations during severe accident conditions and to show that the system can satisfy the design requirements of the EUR. In this paper, analyses were carried out to examine the effectiveness of the HMS incorporated into the Eu- APR1400 design. These analyses were performed using the MAAP (Modular Accident Analysis Program) 4 code. in order to identify whether the HMS could control the average hydrogen concentrations in the containment, such that the concentration would not exceed 10 percent by volume: the analyses also considered whether there was the possibility of inadvertent hydrogen combustion in such processes as FA (Flame Acceleration) and DDT (Deflagration to Detonation Transition)

  5. Moderne Chirurgie der Leisten- und Narbenhernie

    OpenAIRE

    Lauscher, Johannes Christian

    2014-01-01

    Inguinal and incisional hernias belong to the most frequent diseases in general surgery. Our studies show a relevant change of the surgical treatment of inguinal hernias in the last 15 years. Repair with mesh has become standard, the rate of outpatient surgery is rising and the length of hospital stay of the inpatients is decreasing. The recurrence rate could be reduced due to mesh repair but the rate of chronic groin pain and dysesthesia after inguinal hernia repair is relevant. Minimal i...

  6. Gadolinia-bearing Assembly Design for Reduction of Critical Boron Concentration in APR 1400

    Energy Technology Data Exchange (ETDEWEB)

    Wan, Shakirah; Wan, Abdul Kahar; Hah, Chang Joo [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of); Seong, Ki Bong; Chang, Do Ik [Korea Nuclear Fuel Company, Daejeon (Korea, Republic of)

    2013-10-15

    The objective of this study is to develop a systematic approach to further reduce CBC at BOC and ultimately making MTC more negative, while maintaining cycle length and keeping pin peaking factor below the 1.55 safety limit. The methodology uses fuel assembly (FA) designs that contain both low and high Gd w/o rods. The APR 1400 fuel assembly and core design for Shin-Kori Unit 3 Cycle 1 (SK3C1), which is of PWR type, is used as reference case. The Gd-bearing assembly types in SK3C1, namely B1, B2, B3, C1, C2, and C3, uses Gd rods with 8 w/o gadolinia (Gd{sub 2}O{sub 3}) admixed in UO{sub 2}, and 2 w/o U-235 enrichment. FA and core depletions are simulated using CASMO 3.0 and MASTER 3.0 design codes, respectively. The methodologies described in Section 2 are applied to assemblies B1, C1 and C3. Interpolation of these assemblies' quadratic model equations is performed using the 0.11 factor to obtain Δk{sub FA} tables for B2, B3 and C2 assemblies. Once the design of all Gd-bearing assemblies are determined, core depletion is simulated. The summary of core depletion results is shown in Table II. It is clear that CBC at BOC is successfully reduced in the optimized core case, as also evident in Fig. 3. The amount of CBC reduction is less than the predicted 300 ppm. This is attributed to neutron leakage in core depletion simulation. The actual Δk{sub FA} computed using results of the optimized core simulation is 0.078, which is well within the 1% error of the quadratic model solutions and close to the analytically calculated value. Thus, the assumption made in Eq. is validated.

  7. Review on the NEI Methodology of Debris Transport Analysis in Sump Blockage Issue for APR1400

    International Nuclear Information System (INIS)

    Since USNRC (United State Nuclear Regulatory Committee) initially addressed post-accident sump performance under Unresolved Safety Issue USI A-43, sump blockage issue has gone through GSI-191, Regulation Guide 1.82, Rev. 3 (RG. 1.82 Rev.3), and generic Letter 2004-02 for PWRs (Pressurized Water Reactors). As a response of these USNRC's activities, NEI 04-07 was issued in order to evaluate the post-accident performance of a plant's recirculation sump. The baseline methodology of NEI 04-07 is composed of break selection, debris generation, latent debris, debris transport, and head loss. In analytical refinement of NEI 04-07, computational fluid dynamic (CFD) is suggested for the evaluation of debris transport in emergency core cooling (ECC) recirculation mode as guided by RG. 1.82 Rev.3. In Korea nuclear industry also keeps step with international activities of this safety issue, with Kori 1 plant as a pioneering edge. Korean nuclear industry has been also pursuing development of an advanced PWR of APR1400, which incorporates several improved safety features. One of the key features, considering sump blockage issue, is the adoption of IRWST (In-containment Refueling Water Storage Tank). This device, as the acronym implies, changes the emergency core cooling water injection pattern. This fact makes us to review the applicability of NEI 04-07's methodology. In this paper we discuss the applicability of NEI 04- 07's methodology, and more over, new methodology is proposed. And finally the preliminary debris transport is analyzed

  8. Analysis of severe accident progression for in-vessel corium retention estimation in the APR 1400

    International Nuclear Information System (INIS)

    The scope and content of this technical report is to evaluate high-pressure transients of total Loss of Feed Water (LOFW) to the steam generators and Station Blackout (SBO), and low-pressure transients of Loss of Coolant Accident (LOCA) without Safety Injection (SI) using the SCDAP/RELAP5/MOD3.3 computer code from transient initiation to reactor vessel failure in the APR 1400. The SCDAP/RELAP5/MOD3.3 results have shown that the pressurizer surge line had failed before reactor vessel failure, which results in a rapid decrease of RCS pressure in the high-pressure sequences of the LOFW and the SBO transients. The LOFW with intentional RCS depressurization using the safety depressurization system prevents failure of the pressurizer surge line and results in actuation of the safety injection tanks. A large mass of the melted and relocated core material in the bottom of core region at approximately 6 hours was relocated to the lower plenum of the reactor vessel in the 2-inch and the 3-inch SBLOCAs, which results in the reactor vessel failure by creep. In the SBLOCA sequence without the safety injection, the actuation of the SITs can be possible for the operator to have time of 4-5 hours in the action of the severe accident mitigation strategy to prevent reactor vessel failure. In all sequences, approximately 50-90 % of the core material was melted and relocated to the lower plenum of the reactor vessel at the time of reactor vessel failure and approximately 30-60 % of the fuel rod cladding was oxidized

  9. Development of an amphibious robot for visual inspection of APR1400 Npp IRWST strainer

    International Nuclear Information System (INIS)

    An amphibious inspection robot system (hereafter AIROS) is being developed to visually inspect the in-containment refueling storage water tank (hereafter IRWST) strainer in APR1400 instead of a human diver. Four IRWST strainers are located in the IRWST, which is filled with boric acid water. Each strainer has 108 sub-assembly strainer fin modules that should be inspected with the VT-3 method according to Reg. guide 1.82 and the operation manual. AIROS has 6 thrusters for submarine voyage and 4 legs for walking on the top of the strainer. An inverse kinematic algorithm was implemented in the robot controller for exact walking on the top of the IRWST strainer. The IRWST strainer has several top cross braces that are extruded on the top of the strainer, which can be obstacles of walking on the strainer, to maintain the frame of the strainer. Therefore, a robot leg should arrive at the position beside the top cross brace. For this reason, we used an image processing technique to find the top cross brace in the sole camera image. The sole camera image is processed to find the existence of the top cross brace using the cross edge detection algorithm in real time. A 5-DOF robot arm that has multiple camera modules for simultaneous inspection of both sides can penetrate narrow gaps. For intuitive presentation of inspection results and for management of inspection data, inspection images are stored in the control PC with camera angles and positions to synthesize and merge the images. The synthesized images are then mapped in a 3D CAD model of the IRWST strainer with the location information. An IRWST strainer mock-up was fabricated to teach the robot arm scanning and gaiting. It is important to arrive at the designated position for inserting the robot arm into all of the gaps. Exact position control without anchor under the water is not easy. Therefore, we designed the multi leg robot for the role of anchoring and positioning. Quadruped robot design of installing sole

  10. Development of an amphibious robot for visual inspection of APR1400 Npp IRWST strainer

    Energy Technology Data Exchange (ETDEWEB)

    Jang, You Hyun; Kim, Jong Seog [Korea Hydro Nuclear Power Central Research Institute, Daejeon (Korea, Republic of)

    2014-06-15

    An amphibious inspection robot system (hereafter AIROS) is being developed to visually inspect the in-containment refueling storage water tank (hereafter IRWST) strainer in APR1400 instead of a human diver. Four IRWST strainers are located in the IRWST, which is filled with boric acid water. Each strainer has 108 sub-assembly strainer fin modules that should be inspected with the VT-3 method according to Reg. guide 1.82 and the operation manual. AIROS has 6 thrusters for submarine voyage and 4 legs for walking on the top of the strainer. An inverse kinematic algorithm was implemented in the robot controller for exact walking on the top of the IRWST strainer. The IRWST strainer has several top cross braces that are extruded on the top of the strainer, which can be obstacles of walking on the strainer, to maintain the frame of the strainer. Therefore, a robot leg should arrive at the position beside the top cross brace. For this reason, we used an image processing technique to find the top cross brace in the sole camera image. The sole camera image is processed to find the existence of the top cross brace using the cross edge detection algorithm in real time. A 5-DOF robot arm that has multiple camera modules for simultaneous inspection of both sides can penetrate narrow gaps. For intuitive presentation of inspection results and for management of inspection data, inspection images are stored in the control PC with camera angles and positions to synthesize and merge the images. The synthesized images are then mapped in a 3D CAD model of the IRWST strainer with the location information. An IRWST strainer mock-up was fabricated to teach the robot arm scanning and gaiting. It is important to arrive at the designated position for inserting the robot arm into all of the gaps. Exact position control without anchor under the water is not easy. Therefore, we designed the multi leg robot for the role of anchoring and positioning. Quadruped robot design of installing sole

  11. Analysis of MSGTR events for APR1400 by means of best estimate thermal-hydraulic system code

    International Nuclear Information System (INIS)

    A multiple steam generator tube rupture (MSGTR) event has never occurred in the history of commercial nuclear reactor operation while single steam generator tube rupture (SGTR) event is reported to occur every two years. As there is no history of MSGTR event, the understandings of transients and consequences of this event are not so much. In this study, a postulated MSGTR event in advanced power reactor 1400 (APR1400) is analyzed using thermal-hydraulic system code. The APR 1400 is a two-loop, 1000 MWe, PWR supposed to be built in 2009. MARS1.4 is used in this study. The present study aims to understand the effects of rupture location in heat transfer tubes and selection of affected steam generator following a MSGTR event. The effects of five tube rupture locations are compared with each other. The comparison shows that the response of APR1400 is to allow shortest time for operator action following a tubes rupture in the vicinity of hot-leg side tube sheet and to allow longest time following a tube ruptures at the tube top. The MSSV lift time for rupture at tube-top is evaluated as 24.5% larger than that for rupture at hot-leg side tube sheet. Also, the MSSV lift time for four cases are compared in order to examine how long operator response time is allowed depending on which steam generator is affected. The comparison shows that the cases for both of two steam generators are affected allow longer time for operator action compared with the cases that a single steam generator is affected. Further more, the tube ruptures in the steam generator where a pressurizer is linked leads to the shortest operator response time

  12. Multi-analytical characterisation of D’Aprés Cormon by José Veloso Salgado

    Energy Technology Data Exchange (ETDEWEB)

    Cardeira, A.M. [Faculdade de Belas-Artes da Universidade de Lisboa, Largo da Academia Nacional de Belas-Artes, 1249-058 Lisboa (Portugal); Centro de Física Atómica da Universidade de Lisboa, Av. Professor Gama Pinto 2, 1649-003 Lisboa (Portugal); Longelin, S. [Centro de Física Atómica da Universidade de Lisboa, Av. Professor Gama Pinto 2, 1649-003 Lisboa (Portugal); Costa, S.; Candeias, A. [Laboratório José de Figueiredo, Direcção Geral do Património Cultural, Rua das Janelas Verdes 37, 1249-018 Lisboa (Portugal); Laboratório HERCULES e Centro de Química de Évora, Universidade de Évora, Largo Marquês de Marialva 8, 7000 Évora (Portugal); Carvalho, M.L. [Centro de Física Atómica da Universidade de Lisboa, Av. Professor Gama Pinto 2, 1649-003 Lisboa (Portugal); Manso, M., E-mail: marta974@cii.fc.ul.pt [Centro de Física Atómica da Universidade de Lisboa, Av. Professor Gama Pinto 2, 1649-003 Lisboa (Portugal)

    2014-07-15

    This case study reveals the analytical characterisation carried out on ‘D’Aprés Cormon’ (1891) by Veloso Salgado, a copy of ‘Caïn’ (1880) by Fernando Cormon, belonging nowadays to Musée d’Orsay. Infrared Reflectography made in situ revealed underdrawing grid that was used to transpose the original painting to a smaller scale, pictorial style, execution method and retouched/restored areas. In situ EDXRF analysis together with Raman microscopy allowed the identification of gypsum, lead white, titanium white, yellow ochre, vermilion, ultramarine and lamp black. These results provide valuable information about the Salgado’s palette and his production technique.

  13. Preliminary design of S-CO{sub 2} Brayton cycle for APR-1400 with power generation and desalination process

    Energy Technology Data Exchange (ETDEWEB)

    Bae, Seong Jun; Lee, Won Woong; Jeong, Yong Hoon; Lee, Jeong Ik [KAIST, Daejeon (Korea, Republic of); Yoon, Ho Joon [KUSTAR, Abu Dhabi (United Arab Emirates)

    2015-10-15

    This study was conducted to explore the capabilities of the S-CO{sub 2} Brayton cycle for a cogeneration system for APR-1400 application. Three concepts of the S-CO{sub 2} simple recuperated co-generation cycle were designed. A supercritical CO{sub 2} (S-CO{sub 2}) Brayton cycle is recently receiving significant attention as a promising power conversion system in wide range of energy applications due to its high efficiency and compact footprint. The main reason why the S-CO{sub 2} Brayton cycle has these advantages is that the compressor operates near the critical point of CO{sub 2} (30.98 .deg. C, 7.38MPa) to reduce the compression work significantly compared to the other Brayton cycles. In this study, the concept of replacing the entire steam cycle of APR-1400 with the S-CO{sub 2} Brayton cycle is evaluated. The power generation purpose S-CO{sub 2} Brayton cycles are redesigned to generate power and provide heat to the desalination system at the same time. The performance of these newly suggested cycles are evaluated in this paper. The target was to deliver 147MW heat to the desalination process. The thermal efficiencies of the three concepts are not significantly different, but the 3{sup rd} concept is relatively simpler than other cycles because only an additional heat exchanger is required. Although the 2{sup nd} concept is relatively complicated in comparison to other concepts, the temperatures at the inlet and outlet of the DHX are higher than that of the others. As shown in the results, the S-CO{sub 2} Brayton cycles are not easy to outperform the steam cycle with very simple layout and general design points under APR-1400 operating condition. However, this study shows that the S-CO{sub 2} Brayton cycles can be designed as a co-generation cycle while producing the target desalination heat with a simple configuration. In addition, it was also found that the S-CO{sub 2} Brayton cycle can achieve higher cycle thermal efficiency than the steam power cycle under

  14. Ville nouvelle, quarante ans après : les pionniers vieillissants de Maurepas

    Directory of Open Access Journals (Sweden)

    Marie Peretti-Ndiaye

    2009-01-01

    Full Text Available Construites à partir des années 1960 sous l’impulsion du Schéma directeur d’Aménagement et d’Urbanisme de 1965, cinq villes nouvelles ont vu le jour en région parisienne. Leur aménagement laisse entrevoir une volonté de répondre à des besoins urbains identifiés, se conjuguant parfois avec l’offre d’espaces, de services ou d’équipements envisagés alors comme novateurs. Maurepas, rattachée jusqu’en 1984 à l’agglomération nouvelle de Saint-Quentin-en-Yvelines, a été façonnée en partie par ces aspirations. Elle constitue aujourd’hui une commune à la population vieillissante et à l’urbanisme marqué par des jeux d’échelle, des cloisonnements et par une relative uniformité. La configuration de la ville laisse entrevoir la volonté d’ébaucher « un nouveau genre de vie urbaine »(Pachaud, 2006 manifeste durant les années soixante et soixante-dix tandis que l’histoire de la commune permet d’envisager les difficultés inhérentes à l’intercommunalité. Au cœur de cette histoire se retrouvent des ménages de la classe moyenne, entrés dans le périurbain comme des pionniers. Portés par l’idéologie d’une ville-nouvelle où « tout est à construire » et qui leur ouvrait, parallèlement, des perspectives nouvelles en termes « d’espaces à soi », ces derniers sont aujourd’hui âgés de plus de soixante ans. Quarante ans après leur installation, leurs discours sur la ville révèlent l’existence de plusieurs ordres de tension : tension entre ruralité et urbanité, d’une part, tension entre adhésion, différenciation et réflexivité, de l’autre. Ces tensions peuvent être mises en parallèle avec les évolutions de la ville et la façon dont les formes urbaines sont mises en question dans l’espace des débats publics. Ces différents éléments nous conduiront à envisager les résistances et les projections à l’œuvre ainsi que les processus de subjectivation qu’elles r

  15. A Bayesian inversion for slip distribution of 1 Apr 2007 Mw8.1 Solomon Islands Earthquake

    Science.gov (United States)

    Chen, T.; Luo, H.

    2013-12-01

    On 1 Apr 2007 the megathrust Mw8.1 Solomon Islands earthquake occurred in the southeast pacific along the New Britain subduction zone. 102 vertical displacement measurements over the southeastern end of the rupture zone from two field surveys after this event provide a unique constraint for slip distribution inversion. In conventional inversion method (such as bounded variable least squares) the smoothing parameter that determines the relative weight placed on fitting the data versus smoothing the slip distribution is often subjectively selected at the bend of the trade-off curve. Here a fully probabilistic inversion method[Fukuda,2008] is applied to estimate distributed slip and smoothing parameter objectively. The joint posterior probability density function of distributed slip and the smoothing parameter is formulated under a Bayesian framework and sampled with Markov chain Monte Carlo method. We estimate the spatial distribution of dip slip associated with the 1 Apr 2007 Solomon Islands earthquake with this method. Early results show a shallower dip angle than previous study and highly variable dip slip both along-strike and down-dip.

  16. Feed and Bleed Operation Analysis during Total Loss of Feedwater Accident for Supporting the PSA of APR+

    International Nuclear Information System (INIS)

    For estimating the safety of APR+ design, the probabilistic safety assessment (PSA) is performed. This paper discusses the minimum success criteria for successful feed and bleed procedure verified and decided when the secondary cooling is failed during Total loss of feedwater (TLOFW) accident. For verifying whether the equipment conditions proposed is enough to manage the transient event without core damage, the analysis is performed by RELAP5/MOD 3.3 code. During TLOFW event, the operator's action time is allowed for 80 minutes and the uncovered core could maintain the stable state for a long time, about a half or one hour by the positive effects given by the fast coolant circulation by RCP pump operation. In simulations considering test scenarios, the minimum required equipment for successful F and B managing during TLOFW without LOOP is verified that it is that F and B procedure could be performed successfully as if the operator would open at least one out of four POSRV within 80 minutes after secondary cooling failure for the RCS depressurization. These analysis results can be used for contribute more realistic and accurate performance of a APR+ PSA

  17. Thermal-Hydraulic Integral Effect Test Result on the Steam Generator Tube Rupture Accident in the APR1400

    International Nuclear Information System (INIS)

    A postulated SGTR (Steam Generator Tube Rupture) event of the APR1400 was experimentally investigated with the thermal-hydraulic integral effect test facility, ATLAS (Advanced Thermal-hydraulic Test Loop for Accident Simulation). It is generally known that the leak flow rate from the primary to the secondary side is the most important factor affecting the overall thermalhydraulic behaviors such as the depressurization rate of the RCS system, the water level increase and pressurization rate of the secondary system, and the consequent MSSV opening time, etc. As one of the most limiting SGTR accidents, a leak flow equivalent to a double-ended rupture of single and five U-tubes was simulated in this study. The main objectives of these tests were not only to provide physical insight into the system response of the APR1400 reactor during a transient situation of the SGTR but also to present integral effect test data for the validation of the SPACE (Safety and Performance Analysis Computer Code), which is now under development by the Korean nuclear industry

  18. Unit Risk Quotient (RQ) and Relative Significance of Radionuclide on Flora and Fauna to the EU-APR Optimization

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Keunsung [KHNP-CRI, Daejeon (Korea, Republic of); Kim, Sukhoon [FNC Technology Co., Ltd., Yongin (Korea, Republic of); Lee, Chonghui [KEPCO E and C, Yongin (Korea, Republic of)

    2015-05-15

    As part of the project for acquiring the certification from EUR organization, in accordance with Articles 4.8 and 5.5 specified in Section 2.20 of EUR Volume 2, the effects of ionizing radiation from the standard design of EU-APR on biota and ecosystems during operation and decommissioning phases shall be assessed. This assessment must be carried out according to the ERICA (i.e. Environmental Risk from Ionizing Contaminants: Assessment and management) integrated approach. This paper describes the evaluation results for unit risk quotient and relative significance by radionuclide derived from performing Tier 1 assessment on flora and fauna for the EU-APR design using ERICA Tool. As specified previously, Pa-231 and Th-228 are the most significant for the terrestrial and for the marine/freshwater ecosystems, respectively. And, in terms of environmental risk, those radionuclides having the most impact on flora and fauna are relatively more significant than isotope having the least impact by about 7 to 10 orders of magnitude.

  19. [Preparation and Identification of High Immunogenic A/PR/8/34 Maternal Strain HA Protein for Influenza Virus Classical Reassortment].

    Science.gov (United States)

    Tang, Jing; Xin, Li; Guo, Junfeng; Zhu, Wenfei; Zhang, Heyuan; Lang, Shaohui; Wang, Dayan; Shu, Yuelong

    2016-03-01

    Preparation of maternal strain A/PR/8/34 HA antiserum for influenza virus classical reassortment. A/PR/8/34 virus was digested by bromelain after inactivation and purification. 5%-20% sucrose continuous density gradient centrifugation method was used to purify HA protein. SIRD method was used to select the target protein. SDS-PAGE method was used to identified HA protein. High Immunogenic A/PR/8/34 HA protein was successfully prepared and HI titer reached 10240. High purity HA antiserum was identified by SIRD method. The key reagent in the classical reassortment of influenza virus was prepared, and the complete set of technical methods were explored, which laid the foundation for the independent research and development of seasonal influenza vaccine strains of China. PMID:27396155

  20. Evaluation of Effect of N{sub 2} Gas on the Cooling Capability of Passive Auxiliary Feedwater System (PAFS) in APR+

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Yun Je; Kang, Kyong Ho; Yun, Byong Jo [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2012-05-15

    In Korea, Advanced Power Reactor Plus (APR+) has being developed by adding passive safety features to Advanced Power Reactor 1400MWe (APR1400). Passive Auxiliary Feedwater System (PAFS) is one of passive system adopted in the APR+ to replace the conventional active auxiliary feedwater system. Because PAFS removes decay heat from the reactor core, it is required to verify the performance of PAFS in postulated accidents cases. In addition, an effect of noncondensable gas on the heat removal capability of PAFS should be evaluated since the non-condensable gas may deteriorate a condensation heat transfer through the condensation heat exchanger in PAFS. In this study, the effect of N{sub 2} gas was evaluated using MARS

  1. Brūču aprūpes dokumentācijas izveidošana ambulatorajā praksē

    OpenAIRE

    Sokola, Baiba

    2016-01-01

    Bakalaura darba tēma- “ Brūču aprūpes dokumentācijas izveidošana ambulatorajā praksē. Tēma ir aktuāla, jo pašlaik, 2016.gadā, Latvijas medicīnisko dokumentu lietvedībā nav pieejamas brūču aprūpes protokols, kas ir paredzēts ambulatoriem pacientiem. Darba mērķis ir izveidot brūču aprūpes dokumentāciju ambulatorai praksei. Pētījuma uzdevumi tika izvirzīti, lai sasniegtu pētījuma mērķi. Bakalaura darbā tika izmantoti 36 literatūras avoti, no tiem 17 latviešu valodā, 18 angļu valodā, 1 krievu val...

  2. The subtilisin-like protease AprV2 is required for virulence and uses a novel disulphide-tethered exosite to bind substrates.

    Directory of Open Access Journals (Sweden)

    Ruth M Kennan

    Full Text Available Many bacterial pathogens produce extracellular proteases that degrade the extracellular matrix of the host and therefore are involved in disease pathogenesis. Dichelobacter nodosus is the causative agent of ovine footrot, a highly contagious disease that is characterized by the separation of the hoof from the underlying tissue. D. nodosus secretes three subtilisin-like proteases whose analysis forms the basis of diagnostic tests that differentiate between virulent and benign strains and have been postulated to play a role in virulence. We have constructed protease mutants of D. nodosus; their analysis in a sheep virulence model revealed that one of these enzymes, AprV2, was required for virulence. These studies challenge the previous hypothesis that the elastase activity of AprV2 is important for disease progression, since aprV2 mutants were virulent when complemented with aprB2, which encodes a variant that has impaired elastase activity. We have determined the crystal structures of both AprV2 and AprB2 and characterized the biological activity of these enzymes. These data reveal that an unusual extended disulphide-tethered loop functions as an exosite, mediating effective enzyme-substrate interactions. The disulphide bond and Tyr92, which was located at the exposed end of the loop, were functionally important. Bioinformatic analyses suggested that other pathogenic bacteria may have proteases that utilize a similar mechanism. In conclusion, we have used an integrated multidisciplinary combination of bacterial genetics, whole animal virulence trials in the original host, biochemical studies, and comprehensive analysis of crystal structures to provide the first definitive evidence that the extracellular secreted proteases produced by D. nodosus are required for virulence and to elucidate the molecular mechanism by which these proteases bind to their natural substrates. We postulate that this exosite mechanism may be used by proteases produced by

  3. Simplified study for the proposed APR1400 condenser performance based on EL-DABAA SITE, EGYPT, with respect to BNPP and SHIN KORI NPP

    Energy Technology Data Exchange (ETDEWEB)

    Abdoelatef, M. Gomaa; Rezk, Osama; Lee, YonKwan [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

    2015-10-15

    • Perception of nuclear power as a convenient, economically competitive and viable source of energy which, if introduced in the country, would not only complement the traditional energy sources, but would also promote technological development and serve as an incentive for social and economic progress. In this paper we will introduce APR-1400 as the most likely selected reactor type for 1st Egyptian Nuclear Power Plant. Then we will study the optimized APR-1400 condenser performance based on El-Dabaa site conditions. As the climate conditions, especially the seawater temperatures (intake for the cooling system) having a direct effects on the condenser performance and the overall NPP Efficiency, we studied the seawater temperature change based on EL-Dabaa site conditions and it's feedback on the proposed APR-1400 condenser performance and the NPP efficiency. All of the calculations and analysis had been executed by using KINGS NPA by applying EL-Dabaa seawater temperature variations for the 2 types of APR-1400 Condensers (Shinkori, south Korea and Barakah, UAE), and the main findings were as follow: For the APR-1400 condensers (Shinkori and Barakah) performance • The average difference all over the year for saturation temperature, cooling water outlet temperature, and condenser pressure are 0.135 .deg. C, .05785 .deg. C, and 0.3948 mHgA respectively. This shows that the Barakah condenser performance is not significantly better than the shinkori condenser performance based on EL-Dabaa Conditions, especially if we considered the cost difference between the two condensers designs. For APR-1400 NPPs (Shinkori and Barakah) net efficiency • The average difference all over the year for the power productions and net efficiency are 1.4791 MWe and .00037 %, respectively.

  4. Carcinoïde primitif du rein métastasant après 12 ans

    Science.gov (United States)

    Bacha, Dhouha; Lahmar, Ahlem; Gharbi, Lassad; Slama, Sana Ben; Bouraoui, Saadia; Chatti, Samia; Regaya, Sabeh Mzabi

    2016-01-01

    Les carcinoïdes primitifs du rein sont rares avec une centaine de cas rapportés dans la littérature. Sur le plan histologique, il s'agit d'une tumeur bien différenciée dont la morphologie rejoint souvent celle des carcinoïdes dans les autres localisations. Nous rapportons un cas de carcinoïde primitif du rein survenant chez un homme de 41 ans, découvert à la suite de métastases hépatiques. La tumeur était particulière par son architecture tubulo-papillaire, suggérant à tort le diagnostic de carcinome papillaire du rein. Ce diagnostic a été redressé 12 ans après, à la suite de l'apparition d'autres métastases hépatiques, osseuses et pulmonaires. PMID:27217899

  5. O après-coup e a reconsolidação da memória

    Directory of Open Access Journals (Sweden)

    Graziele Luiza Barizon Scopel Gerbasi

    2015-04-01

    Full Text Available Em diferentes áreas do conhecimento é reconhecido que a memória está sujeita a transformações ao longo do tempo. Partindo desse pressuposto, o objetivo do presente estudo é apresentar uma discussão compreendendo a ideia de que nossas recordações são suscetíveis a transformações e a concepção de après-coup. Há o delineamento de algumas ideias acerca da temporalidade em Psicanálise e do mecanismo de reconsolidação da memória segundo as Neurociências. Utilizando-se tais conceitos, evidenciou-se a viabilidade de se pensar uma interlocução entre a Psicanálise e as Neurociências.

  6. O après-coup e a reconsolidação da memória

    OpenAIRE

    Graziele Luiza Barizon Scopel Gerbasi; Paulo José da Costa

    2015-01-01

    Em diferentes áreas do conhecimento é reconhecido que a memória está sujeita a transformações ao longo do tempo. Partindo desse pressuposto, o objetivo do presente estudo é apresentar uma discussão compreendendo a ideia de que nossas recordações são suscetíveis a transformações e a concepção de après-coup. Há o delineamento de algumas ideias acerca da temporalidade em Psicanálise e do mecanismo de reconsolidação da memória segundo as Neurociências. Utilizando-se tais conceitos, evidenciou-se ...

  7. 返工设备——APR-5000-XLS阵列封装返工系统

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Metcal公司2001年推出阵列封装返工系统,确立了可重复性、精度和温度控制的新标准。该公司最近推出的APR-5000-XLS阵列封装返工系统,再次确立了精确、有成本效益的、最大范围元件类型的返工基准,可处理BGA,CSP,LGA(Land Grid Array),Micro SMD,MLF(Micro-Lead Frame),BCC(Bumped Chip Component)多种封装。

  8. 返工设备——APR-5000-XLS阵列封装返工系统

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    APR-5000-XLS阵列封装返工系统可处理BGA,CSP,LGA(Land Grid Array),Micro SMD,MLF(Micro—Lead Frame),BCC(Bumped Chip Component)多种封装。其可处理的板尺寸达610mm×610mm(24.5″×24.5″),厚度达6.35mm(0.25″)。双程、全空气底部预热,能处理大小不同规格的PCB板。采用5个热电偶输入和闭环RTD温度控制,

  9. Conceptual design of passive containment cooling system with air holdup tanks in the concrete containment of improved APR+

    Energy Technology Data Exchange (ETDEWEB)

    Jeon, Byong Guk; NO, Hee Cheon, E-mail: hcno@kaist.ac.kr

    2014-02-15

    Highlights: • Conceptual design of passive containment cooling system (PCCS) based on APR+ is proposed. • Decay heat removal rate is to be maximized by introducing air holdup tanks (AHT). • Only air is transported into the AHT decreasing air mass fraction near HXs inside containment and increasing heat transfer rates. • Large AHT volume gives significantly higher heat removal rate. • External HXs have merits over in-tube HXs for long term cooling. - Abstract: The accident of the Fukushima nuclear power plant emphasized passive systems against prolonged station blackout. This paper aims at conceptual design of passive containment cooling system (PCCS) based on APR+, an advanced PWR developed in Korea with passive auxiliary feedwater system (PAFS). In the design, decay heat removal rate is to be maximized by introducing air holdup tanks (AHT). The AHT is an isolated space disposed above IRWST and is connected to the containment free space by vent lines through IRWST water and PAFS heat exchangers (HXs), where steam generated by decay heat is condensed. Since a lot of steam is condensed through in-tube HXs and IRWST water, air is mainly transported into the AHT decreasing air mass fraction near HXs inside containment and increasing heat transfer rates. Several design options (AHT volume, flow distribution in vent lines, HX types) are evaluated via scoping analysis. The scoping analysis had proved that AHT (>10% containment volume) decreased the required number of PCCS HXs to be installed less than a half, failure of valves caused marginal increase in HXs to be installed, and external HXs had merits over in-tube HXs for long term cooling.

  10. A Quantitative Feasibility Study on Potential Safety Improvement Effects of Advanced Safety Features in APR-1400 when Applied to OPR-1000

    Energy Technology Data Exchange (ETDEWEB)

    Ualikhan Zhiyenbayev [KAIST, Daejeon (Korea, Republic of); Chung, Dae Wook [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2015-10-15

    This study aims to test the feasibility of the applications using Probabilistic Safety Assessment (PSA). Particularly, three of those advanced safety features are selected as follows: 1. Providing an additional Emergency Diesel Generator (EDG); 2. Increasing the capacity of Class 1E batteries; 3. Placing a Refueling Water Storage Tank (RWST) inside containment, i.e., change from RWST to IRWST. The Advanced Power Reactor 1400 (APR-1400) adopts several advanced safety features compared to its predecessor, the Optimized Power Reactor 1000 (OPR-1000), which includes an additional Emergency Diesel Generator, increase in battery capacity, in-containment refueling water storage tank (IRWST), and so on. Considering the remarkable advantages of these safety features in safety improvement and the design similarities between APR-1400 and OPR-1000, it is feasible to apply key advanced safety features of APR-1400 to OPR-1000 to enhance the safety. The selected safety features are incorporated into OPR-1000 PSA model using the Advanced Information Management System (AIMS) for PSA and CDFs are re-evaluated for each application and combination of three applications. Based on current results, it is concluded that three of key advanced safety features of APR-1400 can be effectively applied to OPR-1000, resulting in considerable safety improvement. In aggregate, three advanced safety features, which are an additional EDG, increased battery capacity and IRWST, can reduce the CDF of OPR-1000 by more than 15% when applied altogether.

  11. Synthesis of Key Points from the OSEP Early Childhood Transition FAQ (SPP/APR Indicators C-8, B-11 and B-12)

    Science.gov (United States)

    Diefendorf, M.; Henson, J.; Lucas, A.; Whaley, K.

    2010-01-01

    This document is a synthesis of the key points provided in the Office of Special Education Programs (OSEP) Early Childhood Transition FAQs: SPP/APR indicators C-8 and B-12 released on December 1, 2009. It was developed to assist states with the implementation of effective transition policies and practices. The following is included: (1) Transition…

  12. Le don après un décès d'origine cardiocirculatoire au Canada

    Science.gov (United States)

    Shemie, Sam D.; Baker, Andrew J.; Knoll, Greg; Wall, William; Rocker, Graeme; Howes, Daniel; Davidson, Janet; Pagliarello, Joe; Chambers-Evans, Jane; Cockfield, Sandra; Farrell, Catherine; Glannon, Walter; Gourlay, William; Grant, David; Langevin, Stéphan; Wheelock, Brian; Young, Kimberly; Dossetor, John

    2006-01-01

    Résumé Ces recommandations sont le fruit d'un processus multidisciplinaire national ayant duré un an et visant à déterminer si et comment l'on pourrait procéder au don d'organes après un décès d'origine cardiocirculatoire («don après le décès cardiocirculatoire», ou DDC) au Canada. Le forum national organisé en février 2005 a permis aux participants de discuter et d'élaborer des recommandations sur les principes, interventions et pratiques se rapportant au DDC. Les aspects éthiques et juridiques ont été abordés dans les discussions. À la fin du Forum, la majorité des participants ont été favorables à l'implantation de programmes de DDC au Canada. Les participants du Forum ont également convenu qu'il fallait formuler et prôner des valeurs fondamentales pour orienter l'élaboration de programmes et de protocoles basés sur le cadre médical, éthique et juridique établi lors de cette réunion. Même si la possibilité d'un don d'organes et de tissus doit faire partie intégrante des soins de fin de vie, il faut insister sur le fait que le devoir de diligence envers les patients mourants et leurs familles doit demeurer la priorité des équipes soignantes. La complexité et les répercussions profondes du décès sont reconnues et doivent être respectées, de même que les différences personnelles, ethnoculturelles et religieuses face à la mort et au don d'organes. Les décisions d'arrêter le traitement de maintien des fonctions vitales, la prise en charge des derniers moments de la vie et le diagnostic de décès selon des critères cardiocirculatoires doivent être distincts et indépendants des processus de don et transplantation. Ce rapport contient des recommandations destinées aux gestionnaires de program, aux autorités sanitaires régionales et aux instances appelés à élaborer les protocoles de DDC. Les programmes doivent être conçus en fonction des éléments suivants : direction et planification locales, éducation et

  13. A systematic core design method for reduction of critical boron concentration in APR 1400 with gadolinia-bearing assembly

    International Nuclear Information System (INIS)

    Highlights: • A systematic core design method reduces CBC of APR 1400. • The core design method solves a non-linear programming problem. • The solution is a set of new Gd-bearing fuel assembly design. • LP loading new Gd-bearing fuel assembly designs achieves target CBCs. • Lower L/H ratio shows longer hold-down effect than higher L/H ratio. - Abstract: A systematic core design method is developed to design Gd-bearing fuel assembly having two types of Gd rods, low-wt%-Gd rod and high-wt%-Gd rod. The purpose of the method is to lower the critical boron concentration (CBC) of a preliminary core loading pattern, and consequently to achieve more negative or less positive moderator temperature coefficient (MTC). The proposed core design method is a process of solving a non-linear programming problem stated with a system of equations. In this method, both the ratio of the number of low-wt%-Gd rod to the number of high-wt%-Gd rod (r) and the assembly average Gd wt% (w) are the solution variables of the system of equations. The target function is the amount of soluble boron concentration reduction, ΔCBC, which is correlated with the reactivity change, ΔkFA, per Gd-bearing fuel assembly by a quadratic reactivity equation. The coefficients of the quadratic equations are calculated prior to the determination of Gd-bearing fuel assembly pattern, using the least square method. The constraints required to determine (r, w) are physically realizable Gd rods pattern, Δki close to ΔkFA derived from ΔCBC, etc. An objective function, min[f(∑i(ΔkFA-Δki))], enables a final loading pattern to reach a target CBC. This design methodology is applied to APR 1400. Total six cases with various target CBCs are investigated to validate the proposed method. CASMO-3/MASTER calculations with new design assemblies produce lower CBCs at BOC than target CBCs keeping maximum pin power below the safety limit, and thus show more negative MTC

  14. APR-246/PRIMA-1(MET) rescues epidermal differentiation in skin keratinocytes derived from EEC syndrome patients with p63 mutations.

    Science.gov (United States)

    Shen, Jinfeng; van den Bogaard, Ellen H; Kouwenhoven, Evelyn N; Bykov, Vladimir J N; Rinne, Tuula; Zhang, Qiang; Tjabringa, Geuranne S; Gilissen, Christian; van Heeringen, Simon J; Schalkwijk, Joost; van Bokhoven, Hans; Wiman, Klas G; Zhou, Huiqing

    2013-02-01

    p53 and p63 share extensive sequence and structure homology. p53 is frequently mutated in cancer, whereas mutations in p63 cause developmental disorders manifested in ectodermal dysplasia, limb defects, and orofacial clefting. We have established primary adult skin keratinocytes from ectrodactyly, ectodermal dysplasia, and cleft lip/palate (EEC) syndrome patients with p63 mutations as an in vitro human model to study the disease mechanism in the skin of EEC patients. We show that these patient keratinocytes cultured either in submerged 2D cultures or in 3D skin equivalents have impaired epidermal differentiation and stratification. Treatment of these patient keratinocytes with the mutant p53-targeting compound APR-246/PRIMA-1(MET) (p53 reactivation and induction of massive apoptosis) that has been successfully tested in a phase I/II clinical trial in cancer patients partially but consistently rescued morphological features and gene expression during epidermal stratification in both 2D and 3D models. This rescue coincides with restoration of p63 target-gene expression. Our data show that EEC patient keratinocytes with p63 mutations can be used for characterization of the abnormal molecular circuitry in patient skin and may open possibilities for the design of novel pharmacological treatment strategies for patients with mutant p63-associated developmental abnormalities. PMID:23355676

  15. General arrangement design optimization of emergency response facility (TSC, OSC) in Korea next generation reactor (APR-1400)

    International Nuclear Information System (INIS)

    The accident at the Three Mile Island (TMI) led to install some data processing and display equipment to assist control room personnel in rapidly evaluating the safety status. And also to place in the plant for providing operators with technical support and an emergency response center for radiological environmental assessments and determination of recommended public protective action during emergency. In practice, most of the countries possessing nuclear power plants including USA have partially or wholly adopted US NRC regulations and guidelines for Emergency Response Facility(ERF). Also the Korea nuclear power plants are implementing or operating ERF and SPDS after analyzing US NRC regulations and guideline since TMI accident. So this paper first been reviewed Korea Regulations, US NRC published codes and standards related to ERF (TSC/OSC). Finally this paper is described the design optimization of general arrangement in emergency response facility to improve emergency response capability in Korea Next Generation Reactor(APR-1400), which are best suitable for our domestic situation and also enhance the emergency response capability of ERF

  16. Development of a Phenomena Identification Ranking Table (PIRT) for a Station Black Out (SBO) Accident of the APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Kyoung Ho; Yun, Byong Jo; Sim, Suk Ku and others

    2013-10-15

    SBO is one of the most important DEC in that without any proper operator actions, a total loss of heat sink leads to core uncover, to core damage, and ultimately a core melt-down scenario under high pressure. Due to this safety importance, SBO is considered to be a base test item of the OECD-ATLAS project. In this study, Phenomena Identification Ranking Table (PIRT) has been developed for identifying the major parameters affecting the thermal-hydraulic phenomena in SBO transients. Development of PIRT for SBO transient is expected to contribute to making strategy for performing a thermal-hydraulic integral effect test with ATLAS which includes determination of proper test conditions and improvement of measurements. The PIRT process used in this study follows the methodology previously applied in the Passive Auxiliary Feedwater System (PAFS) of the APR+ (Advanced Power Reactor Plus). The PIRT has been developed for identifying the major parameters affecting the thermal-hydraulic phenomena during a SBO transient. The PSC was determined to be the core mixture level from the expert panel discussion. As for the major components of the nuclear power plant, the rank of the importance and the knowledge level were summarized for each of the three temporal phases. Taking into account the important phenomena from the PIRT result, it can be confirmed that ATLAS has a capability of simulating the major thermal-hydraulic phenomena during a SBO transient as realistically as possible. The present PIRT is expected to contribute to making strategy for performing a thermal-hydraulic integral effect test with ATLAS in the framework of the OECD-ATLAS project.

  17. Analysis of Post-LOCA Core Inlet Blockage to Evaluate In-vessel Downstream Effect in APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Bang, Young Seok [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2015-10-15

    The method was developed to have a conservatism to cover the uncertainty of analysis and the acceptance is judged by the representative bounding estimation. However, the important safety parameters such as the available driving head need to be confirmed by the plant specific calculation. Also an interaction between the debris induced head loss and the core flow rate needs to be explained because the head loss induced by debris in actual condition may reduce the core inflow rate faster. To confirm the safety parameters, in this study, thermal-hydraulic response considering the core inlet blockage (CIB) by debris during LTCC process following a double-ended guillotine break of cold leg (CLB), one of hot leg (HLB) and one of intermediate leg (ILB) of the APR1400 were calculated, respectively. MARS-KS 1.3 code has been used. The CIB has been modeled by the closure of valves to the core in exponential manner with time to observe the behavior near the complete blockage. To understand the effect of core inlet blockage (CIB) during a long term core cooling (LTCC) phase following a loss-of-coolant accident (LOCA) in the light of in-vessel downstream effect (IDE) of Generic Safety Issue (GSI) 191, double-ended guillotine break of hot leg (HLB), one of cold leg (CLB) and one of intermediate leg (ILB) were calculated, respectively. And the important safety parameters such as the available driving head and the head loss due to debris were calculated using MARS-KS code and discussed in comparison with the WCAP method. As a result, a little delayed heatup behavior of the fuel cladding was found for all the cases, which due to the redistribution of flow within the core after blockage.

  18. PRIMA-1Met/APR-246 induces apoptosis and tumor growth delay in small cell lung cancer expressing mutant p53

    DEFF Research Database (Denmark)

    Zandi, Roza; Selivanova, Galina; Christensen, Camilla Laulund;

    2011-01-01

    Small cell lung cancer (SCLC) is a highly malignant disease with poor prognosis, necessitating the need to develop new and efficient treatment modalities. PRIMA-1(Met) (p53-dependent reactivation of massive apoptosis), also known as APR-246, is a small molecule, which restores tumor suppressor...... function to mutant p53 and induces cancer cell death in various cancer types. Since p53 is mutated in more than 90% of SCLC, we investigated the ability of PRIMA-1(Met) to induce apoptosis and inhibit tumor growth in SCLC with different p53 mutations....

  19. Daugiabučio namo aprūpinimo energija technologinių sprendinių daugiakriterė analizė

    OpenAIRE

    Matuzas, Martynas

    2013-01-01

    Baigiamajame magistro darbe nagrinėjamas tipinis daugiabutis pastatas ir jam pritaikytos energiją generuojančios sistemos. Darbo tikslas – daugiakriterio vertinimo metodu nustatyti optimalų energijos aprūpinimo technologinį sprendinį pagal energinį, ekologinį ir ekonominį kriterijus. Tyrime nagrinėjama centralizuoto šilumos tiekimo sistema, dujinis katilas, oras–vanduo ir gruntas–vanduo šilumos siurbliai, saulės kolektoriai, saulės elementų bei visų šių sistemų kombinacijos. Tyrimui naudojami...

  20. Recovery and radio-resistance in mice after external irradiation; Restauration et radio-resistance chez la souris apres irradiation externe

    Energy Technology Data Exchange (ETDEWEB)

    Le Guillou, S. [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1965-07-01

    The author presents a literature study concerning recovery from external irradiation and an analysis of experimental data (which appear to suggest the idea of a radio-resistance in animals), as well as the hypotheses put forward for explaining this phenomenon. The author then describes an experiment carried out on mice whose LD 50/30 days increased from 1005 to 1380 rads and for which it was shown that an increase occurs in the number of certain anti-bodies circulating after a low dose of {gamma} irradiation. (author) [French] L'auteur presente une etude bibliographique de la restauration apres irradiation externe et une analyse des donnees experimentales qui paraissent suggerer la notion de radioresistance chez les animaux ainsi que les hypotheses cherchant a expliquer ce phenomene. Il relate ensuite une experience realisee sur des souris dont la DL 50/30 jours est passee de 1005 a 1380 rads et dans laquelle est montree l'augmentation de certains anticorps circulant apres une faible dose d'irradiation gamma. (auteur)

  1. Photodiagnostic et chirurgie guidés par la fluorescence

    OpenAIRE

    Mordon, Serge; Bourg-Heckly, Geneviève

    2015-01-01

    Pour de nombreux cancers, plus le diagnostic est réalisé précocement, moins les traitements sont lourds et meilleures sont les chances de guérison. L'utilisation de méthodes optiques de diagnostic précoce, basées sur des mesures de fluorescence (photodiagnostic) repose soit sur une fluorescence naturelle, soit sur la répartition d'un marqueur fluorescent permettant de distinguer le tissu tumoral du tissu sain. En cancérologie, l'ablation chirurgicale complète de la tumeur est un des facteurs ...

  2. Bypassmaterialien in der Gefäßchirurgie

    OpenAIRE

    Eidt, D; Roll, S.; Kulp, W; Müller-Nordhorn, J.; Vauth, C; Greiner, W; Willich, SN; von der Schulenburg, JM

    2006-01-01

    Introduction Arteriosclerotic changes can lead to circulatory disturbances in various areas of the human vascular system. In addition to pharmacological therapy and the management of risk factors (e. g. hypertension, diabetes, lipid metabolism disorders, and lifestyle), surgical interventions also play an important role in the treatment of arteriosclerosis. Long-segment arterial occlusions, in particular, can be treated successfully with bypass sur-gery. A number of different materials are av...

  3. Plastische chirurgie bij patiënten met een aangezichtsverlamming

    NARCIS (Netherlands)

    Werker, P M N

    2007-01-01

    In short-term irreversible paralysis caused by facial nerve problems the aim is to re-innervate the paralysed facial musculature. Whenever a paralysis remains untreated for longer than 12-18 months successful re-innervation is unlikely. In longer-term paralysis the symmetry of the face at rest can b

  4. Chirurgie neuroendokriner Tumoren des Pankreas: Auch bei Vorliegen von Metastasen

    Directory of Open Access Journals (Sweden)

    Angst E

    2010-01-01

    Full Text Available Neuroendokrine Tumoren sind selten und können endokrin aktiv oder inaktiv sein. Moderne Methoden erlauben die genaue Charakterisierung und Verteilung von neuroendokrinen Tumoren. Neben der Bestimmung von Chromogranin A gehört eine Octreotid-Szintigraphie zur Diagnostik. Das Behandlungskonzept kann auf internationalen Richtlinien abgestützt werden und sollte interdisziplinär an großen Zentren erfolgen. Im Pankreas dürfen benigne Tumoren enukleiert werden, maligne Tumoren müssen onkologisch reseziert werden. Auch große Tumormassen oder Lebermetastasen müssen möglichst vollständig operativ entfernt werden, um das Ansprechen der adjuvanten Therapien und die Prognose zu verbessern. Insgesamt haben diese Tumoren auch bei Vorliegen von Metastasen eine gute Langzeitprognose.

  5. L'hypnose et son application en chirurgie.

    OpenAIRE

    Faymonville, Marie; Defechereux, Thierry; Joris, Jean; Adant, J. P.; Hamoir, Etienne; Meurisse, Michel

    1998-01-01

    Since 1992, we have used hypnosis routinely in more than 1400 patients undergoing surgery. We found that hypnosis used in patients as an adjunct to conscious sedation and local anesthesia was associated with improved intraoperative patient comfort, and with reduced anxiety, pain, intraoperative requirements for anxiolytic and analgesic drugs, optimal surgical conditions and a faster recovery of the patient. We reported our clinical experience and our fundamental research. Peer reviewed

  6. Kosteneffectiviteit van bariatrische chirurgie : Een review van economische evaluaties

    NARCIS (Netherlands)

    Suijkerbuijk, Anita; Van Gils, Paul; De Wit, Ardine; Feenstra, Talitha

    2013-01-01

    Synopsis Bariatric surgery appears to be a cost-effective intervention for moderately to severely obese people compared to single lifestyle interventions. This appears from a review of the literature on cost-effectiveness of bariatric surgery. Almost all studies included lifestyle advice before and

  7. Truman, "faith-based" diplomatie et ambigüités du Plan Marshall : cas de la France de l'après-guerre

    OpenAIRE

    Autran, Jean-Marie

    2015-01-01

    La "Faith-based" diplomatie américaine et les ambiguïtés du plan Marshall : le cas de la France dans l’après-guerre. Le Président Harry S. Truman (1945-1953) affirme dès 1946 que les E.U. doivent s’armer d'une « diplomatie fondée sur la foi » pour encourager la reconstruction spirituelle d'une Europe « déchristianisée » face au communisme. Pour faire barrage au marxisme de l’Union Soviétique, il fallait commencer par la France, vue comme la pierre de voûte spirituelle. Plus que toute autre na...

  8. Comprendre le passé : une condition essentille pour la reconstruction des villes de l’après-apartheid et la compensation des victimes

    Directory of Open Access Journals (Sweden)

    Susan Parnell

    1996-04-01

    Full Text Available Seule une approche pragmatique et systématisée du passé peut satisfaire l'opinion publique qui réclame réparation pour les victimes du système de l'apartheid et la construction de cités plus équitables dans l'Afrique du Sud de l'après apartheid. Nous estimons que les politiques raciales, appliquées dans les villes ne doivent pas être considérées isolément dans la mesure où l'apartheid a complètement dénaturé les modèles d'urbanisation. L'héritage des manipulations pratiquées dans les villes a...

  9. La présence des Nabatéens en Italie (ier siècle av.-iie siècle apr. J.-C.)

    OpenAIRE

    Schwentzel, Christian-Georges

    2015-01-01

    La présence des Nabatéens en Italie est attestée par plusieurs documents épigraphiques ainsi que par quelques monuments découverts à Pouzzoles : des autels et des objets de culte, des sculptures. Cette présence s’est sans doute développée à la fin du iie s. av. J.-C., ou au début du ier siècle av. J.-C., avant de s’effacer, probablement au iie siècle apr. J.-C. En tout cas, les documents épigraphiques mentionnant la présence de Nabatéens en Italie sont datés des règnes de Malichos Ier (58-30 ...

  10. The LasB Elastase of Pseudomonas aeruginosa Acts in Concert with Alkaline Protease AprA To Prevent Flagellin-Mediated Immune Recognition.

    Science.gov (United States)

    Casilag, Fiordiligie; Lorenz, Anne; Krueger, Jonas; Klawonn, Frank; Weiss, Siegfried; Häussler, Susanne

    2016-01-01

    The opportunistic pathogen Pseudomonas aeruginosa is capable of establishing severe and persistent infections in various eukaryotic hosts. It encodes a wide array of virulence factors and employs several strategies to evade immune detection. In the present study, we screened the Harvard Medical School transposon mutant library of P. aeruginosa PA14 for bacterial factors that modulate interleukin-8 responses in A549 human airway epithelial cells. We found that in addition to the previously identified alkaline protease AprA, the elastase LasB is capable of degrading exogenous flagellin under calcium-replete conditions and prevents flagellin-mediated immune recognition. Our results indicate that the production of two proteases with anti-flagellin activity provides a failsafe mechanism for P. aeruginosa to ensure the maintenance of protease-dependent immune-modulating functions. PMID:26502908

  11. Precificação de consultoria empresarial com a contribuição das estratégias de apreçamento = Entrepreneurial Counseling Pricing with Pricing Strategy Contribution

    Directory of Open Access Journals (Sweden)

    Nivaldo João dos Santos

    2008-11-01

    Full Text Available A precificação de serviços de consultoria também pode se beneficiar dos conceitos e idéias das estratégias de apreçamento de bens de consumo de massa, especificamente na área de consultoria de gestão empresarial. Apesar deste campo ser dominado por grandes corporações multinacionais, ainda existe espaço para empresas e profissionais nacionais. Por se tratar de mercado que envolve valores de grande magnitude, imaginasse que as instituições de sucesso adotem estratégia de apreçamento. Neste trabalho, estratégias de apreçamento foram selecionadas para exame e verificação de aplicabilidade quando do estabelecimento valor pelos serviços da consultoria de gestão empresarial. O apreçamento de desnatação, apreçamento de penetração, apreçamento neutro e apreçamento baseado em valor tiveram seus conceitos sintetizados para fins de verificação. O apreçamento baseado em valor se revelou o mais propício para este tipo de produto (consultoria e o processo de comunicação é o elemento crítico para evidenciar valor, benefícios e, finalmente, justificar o preço do serviço. A sugestão de roteiro para apreçamento de serviço de consultoria empresarial é apresentada ao final, como resultado da análise das diversas estratégias de apreçamento.The pricing of counseling services may also benefit from strategy concepts and ideas ofmass consumption goods pricing, specifically within the entrepreneurial managementcounseling area. Even though this field has been taken over by big multinationalcorporations, there is still some space for national enterprisings and professionals. As itis a market that involves values of great magnitude, it is thought that successfulinstitutions adopt this pricing strategy. In this study, pricing strategies were selectedfor analysis and applicability checking by the time the price for entrepreneurialmanagement counseling service was established. The skimming pricing, penetratingpricing, neutral

  12. A Study on Scenario Selection for Evaluation of Fission Product Behavior during a Severe Accident at APR 1400 Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, E. S.; Kim, Han-Chul [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of); Cho, Song-Won [NSETec, Daejeon (Korea, Republic of)

    2015-05-15

    As a part of an 'Evaluation of the State-of-the-Art on the Fission Product Behavior and Improvement of the Iodine Evaluation Model' Project, we at KINS plan to investigate source term behavior during a severe accident by MELCOR and to eventually compare it with results by RAIM which is an add-on code to MELCOR including iodine behavior model developed by KINS. Since species and amount of fission products in the containment depend on a specific accident, it is necessary to select accident scenarios for the study, especially taking account of its relative importance of occurrence or resultant effects for a specific plant. In this regard, we have reviewed U.S.NRC's Stateof- the-Art Reactor Consequence Analyses (SOARCA) and applied the SOARCA's method of scenario selection to Probabilistic Safety Assessment (PSA) for Shin-Kori 3·4 nuclear power plants which are APR1400 type reactors. Furthermore, we have selected scenarios from the PSA results with a new criterion in the light of risk, which consists of probability and consequence of accidents of interest. In this study, we have selected scenarios for evaluation of fission product behavior during a severe accident. Applying the U.S.NRC's SOARCA method to Shin-Kori 3·4 PSA revealed that it is practically useful to set a relative criterion for scenario studies since making a definite criterion as in SOARCA requires to consider many spatiotemporal factors such as regulation policies and safety technologies. With this in mind, the relative criterion of the scenario selection has been created using release frequency and release fraction of source term in the respect of risk from APR 1400 type Shin-Kori 3·4 Level 2 PSA. The selected representing scenarios are ISLOCA, SGTR, and SBO. A preliminary analysis has been tried for a SBO sequence with more severe and simple assumptions using MELCOR. The results show early release of volatile elements in the containment.

  13. Development of a New Condensation Heat Transfer Model for the Nearly Horizontal Tube of the APR+ PAFS (Passive Auxiliary Feed-water System)

    International Nuclear Information System (INIS)

    Korea Atomic Energy Research Institute (KAERI) has recently conducted PASCAL experiment to confirm the performance of PAFS. From the work, it is founded that the condensation heat transfer coefficient predicted by best estimated safety analysis code MARS (Multi-dimensional Analysis of Reactor Safety) was underestimated compared to the experimental data. Shah correlation embedded in MARS code is the typical model using the empirical two-phase multiplier to determine condensation heat transfer coefficient for annular flow in the condensing tube. On the other hand, the PASCAL experiment indicated that a stratified-wavy flow generally tends to occur in the downward inclined tube of the condensation heat exchanger. Therefore, in order to improve the prediction capability of safety analysis codes for PAFS, the present study has proposed a new condensation heat transfer model package for the nearly horizontal tube, which determines mechanistically the local heat transfer coefficient based on the flow regimes. To enhance prediction capability of one-dimensional best estimated code MARS for the PAFS of the Korean 3.5 generation nuclear power plant APR+, a new condensation heat transfer model package has been developed. The model package consists of the one-dimensional separated model for the void fraction, a flow regime model based on wetted angle, and the condensation heat transfer correlations. The model package considers the inclination angle of the condensing tube and various flow regimes that are expected in the tube during condensation process

  14. Coseismic Dip Slip Distribution of the 1 Apr 2007 Solomon Islands Mw8.1 Earthquake from a Fully Bayesian Inversion

    Science.gov (United States)

    Chen, T.

    2009-12-01

    102 uplift and subsidence measurements over the southeastern end of the rupture zone from two field surveys shortly after 1 Apr 2007 Solomon Islands Earthquake provide a unique geodetic constraint in the following inversion of distributed slip. In the conventional inversion of geodetic data for spatial distribution of fault slip the solution is maintained by minimizing the second-order spatial derivative of slip and the smoothing parameter is often selected subjectively at the bend of the trade-off curve of misfit as a function of slip roughness. A fully Bayesian slip inversion method[Fukuda et al.,2008] is used to overcome the deficiency of selecting the smoothing parameter subjectively. The smoothing parameter is estimated with the distributed slip at the same time under a unified theoretical Bayesian framework. The joint posterior probability density function of distributed slip and smoothing parameter is formulated using Bayes’ theorem and sampled with Markov chain Monte Carlo method. I will apply this method to coseismic slip distribution associated with the 2007 Mw8.1 Solomon Islands earthquake and compare the results of this method with conventional method and the coseismic finite fault model of Furlong et al.[2009].

  15. Les westerns de John Ford : Du libéralisme d’avant-guerre au conservatisme d’après-guerre

    Directory of Open Access Journals (Sweden)

    Jean-Pierre Esquenazi

    2012-05-01

    Full Text Available L’article propose un moyen de mesurer l’influence sur les cinéastes du milieu dans lequel ils vivent. Sont examinés trois ensembles de westerns de John Ford (réalisés avant guerre, dans l’immédiat après guerre et dans la décennie 1955-1965. Chaque groupe est lié à une situation particulière de l’institution hollywoodienne et de la communauté des cinéastes. L’étude de la mise en scène de scènes récurrentes dans tous ces films révèle des différences pertinentes. Celles-ci peuvent être comprises comme des réactions à l’actualité sociale et politique de Hollywood. The article proposes a way to measure the influence on filmmakers of the environment in which they live. Three wholes of westerns, produced during the pre-war, during the immediate post war and during the decade 1955-1965, are reviewed. Each group is linked to a particular situation of the Hollywood industry. The study of the mise en scene of recurrent scenes in these films reveals relevant differences. These can be understood as reactions to the social and political state of the Hollywood industry.

  16. Observations of TeV gamma-rays from Mrk 421 during Dec. 2005 to Apr. 2006 with the TACTIC telescope

    CERN Document Server

    Yadav, K K; Tickoo, A K; Rannot, R C; Godambe, S; Koul, M K; Dhar, V K; Thoudam, S; Bhatt, N; Bhattacharya, S; Chanchalani, K; Goyal, H C; Kaul, R K; Kothari, M; Kotwal, S; Koul, R; Sahayanathan, S; Sharma, M; Venugopal, K

    2007-01-01

    The TACTIC $\\gamma$-ray telescope has observed Mrk 421 on 66 clear nights from Dec. 07, 2005 to Apr. 30, 2006, totalling $\\sim$ 202 hours of on-source observations. Here, we report the detection of flaring activity from the source at $\\geq$ 1 TeV energy and the time-averaged differential $\\gamma$-ray spectrum in the energy range 1-11 TeV for the data taken between Dec. 27, 2005 to Feb. 07, 2006 when the source was in a relatively higher state as compared to the rest of the observation period. Analysis of this data spell, comprising about $\\sim$97h reveals the presence of a $\\sim 12.0 \\sigma$ $\\gamma$-ray signal with daily flux of $>$ 1 Crab unit on several days. A pure power law spectrum with exponent $-3.11\\pm0.11$ as well as a power law spectrum with an exponential cutoff $(\\Gamma = -2.51\\pm0.26$ and $E_0=(4.7\\pm2.1) TeV)$ are found to provide reasonable fits to the inferred differential spectrum within statistical uncertainties. We believe that the TeV light curve presented here, for nearly 5 months of ext...

  17. Extension of Surveillance Test Interval of Safety Injection Pump for APR-1400 Reactors to Improve Reliability and Availability of the Pump

    Energy Technology Data Exchange (ETDEWEB)

    Osama, A. Rezk; Jung, J. C.; Lee, Yong-Kwan [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

    2015-10-15

    The safety features function to localize, control, mitigate, and terminate such incidents and to hold exposure levels below applicable limits. The safety injection system is comprised of four independent mechanical trains without any tie line among the injection paths and two electrical divisions. Each train has one active Safety Injection Pump (SIP) and one passive Safety Injection Tank (SIT) equipped with a Fluidic Device (FD), each train provides 50% of the minimum injection flow rate for breaks larger than the size of a direct vessel injection line. For breaks equal to or smaller than the size of a direct vessel injection line, each train has 100% of the required capacity. The low pressure injection pumps with common header installed in the conventional design are eliminated, and the functions for safety injection and shutdown cooling are separated. The arrangement of safety injection system for APR-1400 as shown in figure (1). The results obtained in this work show that STI extensions for the SIS feasible without any unacceptable increase in the plant total risk, STI extensions are acceptable for safety injection system to provide plant operational flexibility in the performance of both corrective and preventive maintenance for the safety injection system.

  18. Folate, vitamin B12, and vitamin B6 status of a group of high socioeconomic status women in the Alberta Pregnancy Outcomes and Nutrition (APrON) cohort.

    Science.gov (United States)

    Fayyaz, Faiqa; Wang, Flora; Jacobs, René L; O'Connor, Deborah L; Bell, Rhonda C; Field, Catherine J

    2014-12-01

    Folic acid supplementation and food fortification policies have improved folate status in North American women of child bearing age. Recent studies have reported the possible inadequacy of vitamin B12 and B6 in the etiology of neural tube defects in folate-fortified populations. The aims of this study were to describe folate status and its relationship to supplementation and to assess vitamin B12 and B6 status in a cohort of pregnant women. Supplement intake data were collected in each trimester from the first cohort (n = 599) of the Alberta Pregnancy Outcomes and Nutrition (APrON) study. Red blood cell folate (RBCF) and plasma folate, holotranscobalamin, and pyridoxal 5-phosphate were measured. Overt folate deficiency was rare (3%) but 24% of women in their first trimester had suboptimal RBCF concentration (1360 nmol·L(-1)) was observed in approximately half of the women during each pregnancy trimester. Vitamin B12 and B6 deficiencies were rare (pregnancy and over half the women had abnormally high RBCF, suggesting that supplementation during pregnancy is not appropriate in a cohort of women considered to be healthy and a low risk for nutritional deficiencies.

  19. A study on Requirements of Data Base Translator for APR1400 Computerized Procedure System at Shin-Hanul unit 1 and 2

    Energy Technology Data Exchange (ETDEWEB)

    Seong, Nokyu; Lee, Sungjin [KHNP, Daejeon (Korea, Republic of)

    2015-05-15

    The CPS is one of the Man Machine Interface (MMI) resources and the CPS can directly display plant graphic objects which are in the Digital Control System (DCS). And the CPS can send a request to DCS to provide DCS screen which is called step support display through DCS link button on a computerized procedure. The procedure writers can insert DCS graphic information to computerized procedure through data base which is provided by CPS Editing System (CPSES). The data base which is provided by CPSES conforms to the naming rule of DCS graphic objects. The naming rule of DCS graphic objects is defined by vendor thus status of DCS graphic objects which are in computerized procedure at Shin-Kori plant cannot be displayed on CPS at Shin-Hanul plant. To use computerized procedure which is written by other plant procedure writer, DCS graphic objects shall be translated by its plant data base. This paper introduces requirements of data base translator to reduce translation and re-inserting graphic objects burden. This paper introduces the requirements of data base translator of CPSES for APR1400 CPS at Shin-Hanul unit 1 and 2. The translator algorithms shall be tested to update data base of CPSES effectively. The prototype of translator is implemented and is being tested using real plant DB. This translator can be applied to Shin- Hanul unit1 and 2 through software V and V.

  20. Impaired epithelial differentiation of induced pluripotent stem cells from ectodermal dysplasia-related patients is rescued by the small compound APR-246/PRIMA-1MET.

    Science.gov (United States)

    Shalom-Feuerstein, Ruby; Serror, Laura; Aberdam, Edith; Müller, Franz-Josef; van Bokhoven, Hans; Wiman, Klas G; Zhou, Huiqing; Aberdam, Daniel; Petit, Isabelle

    2013-02-01

    Ectodermal dysplasia is a group of congenital syndromes affecting a variety of ectodermal derivatives. Among them, ectrodactyly, ectodermal dysplasia, and cleft lip/palate (EEC) syndrome is caused by single point mutations in the p63 gene, which controls epidermal development and homeostasis. Phenotypic defects of the EEC syndrome include skin defects and limbal stem-cell deficiency. In this study, we designed a unique cellular model that recapitulated major embryonic defects related to EEC. Fibroblasts from healthy donors and EEC patients carrying two different point mutations in the DNA binding domain of p63 were reprogrammed into induced pluripotent stem cell (iPSC) lines. EEC-iPSC from both patients showed early ectodermal commitment into K18(+) cells but failed to further differentiate into K14(+) cells (epidermis/limbus) or K3/K12(+) cells (corneal epithelium). APR-246 (PRIMA-1(MET)), a small compound that restores functionality of mutant p53 in human tumor cells, could revert corneal epithelial lineage commitment and reinstate a normal p63-related signaling pathway. This study illustrates the relevance of iPSC for p63 related disorders and paves the way for future therapy of EEC. PMID:23355677

  1. Anti-leukaemic effects induced by APR-246 are dependent on induction of oxidative stress and the NFE2L2/HMOX1 axis that can be targeted by PI3K and mTOR inhibitors in acute myeloid leukaemia cells.

    Science.gov (United States)

    Ali, Dina; Mohammad, Dara K; Mujahed, Huthayfa; Jonson-Videsäter, Kerstin; Nore, Beston; Paul, Christer; Lehmann, Sören

    2016-07-01

    The small molecule APR-246 (PRIMA-1(MET) ) is a novel drug that restores the activity of mutated and unfolded TP53 protein. However, the mechanisms of action and potential off-target effects are not fully understood. Gene expression profiling in TP53 mutant KMB3 acute myeloid leukaemia (AML) cells showed that genes which protected cells from oxidative stress to be the most up-regulated. APR-246 exposure also induced reactive oxygen species (ROS) formation and depleted glutathione in AML cells. The genes most up-regulated by APR-246, confirmed by quantitative real time polymerase chain reaction, were heme oxygenase-1 (HMOX1, also termed HO-1), SLC7A11 and RIT1. Up-regulation of HMOX1, a key regulator of cellular response to ROS, was independent of TP53 mutational status. NFE2L2 (also termed Nrf2), a master regulator of HMOX1 expression, showed transcriptional up-regulation and nuclear translocation by APR-246. Down-regulation of NFE2L2 by siRNA in AML cells significantly increased the antitumoural effects of APR-246. The PI3K inhibitor wortmannin and the mTOR inhibitor rapamycin inhibited APR-246-induced nuclear translocation of NFE2L2 and counteracted the protective cellular responses to APR-246, resulting in synergistic cell killing together with APR-246. In conclusion, ROS induction is important for antileukaemic activities of APR-246 and inhibiting the protective response of the Nrf-2/HMOX1 axis using PI3K inhibitors, enhances the antileukaemic effects. PMID:26991755

  2. L’avenir de la PAC après 2013 : la réforme des mécanismes de régulation des marchés

    OpenAIRE

    Chatellier, Vincent

    2009-01-01

    Cette communication propose une analyse portant sur les instruments de la régulation des marchés agricoles au sein de l’Union européenne, dans la perspective des évolutions futures de la PAC pour l’après 2013. Après avoir rappelé l’importance des soutiens budgétaires déployés par la PAC en faveur de la régulation des marchés et discuter des justifications à une intervention publique, l’analyse aborde successivement les droits de douane, les aides à l’exportation, les filets de sécurité (prix ...

  3. L'Arabie du Sud et la mer du IIIème siècle av. au VIème siècle apr. J.‑C.

    OpenAIRE

    Schiettecatte, Jérémie

    2012-01-01

    Etude de l'évolution du commerce maritime en Arabie du Sud du 3e siècle avant au 6e siècle après et de l'évolution des ports et du tracé des voies de navigation en fonction du contexte politique plus large (évolution de l'empire romain, de la Perse sassanide).

  4. Phylogenetic Diversity and Spatial Distribution of the Microbial Community Associated with the Caribbean Deep-water Sponge Polymastia cf. corticata by 16S rRNA, aprA, and amoA Gene Analysis

    OpenAIRE

    Meyer, Birte; Kuever, Jan

    2008-01-01

    Denaturing gradient gel electrophoresis (DGGE)-based analyses of 16S rRNA, aprA, and amoA genes demonstrated that a phylogenetically diverse and complex microbial community was associated with the Caribbean deep-water sponge Polymastia cf. corticata Ridley and Dendy, 1887. From the 38 archaeal and bacterial 16S rRNA phylotypes identified, 53% branched into the sponge-specific, monophyletic sequence clusters determined by previous studies (considering predominantly shallow-water sponge species...

  5. Análise do efeito não linear do patrimônio líquido no apreçamento de fundos de investimento em ações

    Directory of Open Access Journals (Sweden)

    Paulo Rogério Faustino Matos

    2012-01-01

    Full Text Available Este artigo faz uso do Capital Asset Pricing Model (CAPM, em sua versão canônica e com extensões não lineares, visando a apreçar um painel de 75 fundos de investimento em ações no Brasil, ao longo dos últimos 11 anos. O resultado sugere que a versão linear desse arcabouço não seja capaz de apreçar ou de prever retornos reais de fundos que possuam elevados patrimônio líquido (PL e outperformance, em relação ao índice da Bolsa de Valores de São Paulo (Ibovespa, corroborando evidências anteriores. A versão não linear com thresholds baseados no PL parece lidar melhor com a questão de alfas de Jensen significativos, apesar de ser estatisticamente indicada apenas para poucos fundos com elevado PL, mas baixa outperformance. Essa é uma evidência de que, apesar de o tamanho influenciar na gestão e, possivelmente, na performance de um fundo, a modelagem de apreçamento desse efeito deve ser feita linearmente.

  6. "Mēness aptiekas" farmaceitiskās aprūpes pakalpojumu kvalitātes izvērtējums un pilnveides iespējas

    OpenAIRE

    Matute, Anete

    2016-01-01

    Maģistra darbā „Mēness aptiekas” farmaceitiskās aprūpes pakalpojumu kvalitātes izvērtējums un pilnveides iespējas” autore, balstoties uz pakalpojumu kvalitātes novērtēšanas teorētiskajiem modeļiem, izvērtējusi „Mēness aptiekas” tīkla Jūrmalas aptieku sniegto pakalpojumu kvalitātes dažādas dimensijas. Mūsdienu apstākļos farmaceitiskā aprūpe ir kļuvusi par būtisku primārās veselības aprūpes sastāvdaļu, tādēļ šo pakalpojumu pieejamībai un kvalitātei tiek pievērsta aizvien lielāka uzmanība gan ...

  7. A Study on Large Display Panel Design for the Countermeasures against Team Errors within the Main Control Room of APR-1400

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sa Kil; Lee, Yong Hee [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    The personal aspect of human errors has been mainly overcome by virtue of the education and training. However, in the system aspect, the education and training system needs to be reconsidered for more effective reduction of human errors affected from various systems hazards. Traditionally the education and training systems are mainly not focused on team skills such as communication, situational awareness, and coordination, etc. but individual knowledge, skill, and attitude. However, the team factor is one of the crucial issues to reduce the human errors in most industries. In this study, we identify the emerging types of team errors, especially, in digitalized control room of nuclear power plants such as the APR-1400 main control room. Most works in nuclear industry are to be performed by a team of more than two persons. Even though the individual errors can be detected and recovered by the qualified others and/or the well trained team, it is rather seldom that the errors by team could be easily detected and properly recovered by the team itself. Note that the team is defined as two or more people who are appropriately interacting with each other, and the team is a dependent aggregate, which accomplishes a valuable goal. Team error is one of the typical organizational errors that may occur during performing operations in nuclear power plants. The large display panel is a representative feature of digitalized control room. As a group-view display, the large display panel provides plant overview to the operators. However, in terms of team performance and team errors, the large display panel is on a discussion board still because the large display panel was designed just a concept of passive display. In this study, we will propose revised large display panel which is integrated with several alternative interfaces against feasible team errors.

  8. Coadministration of Hedera helix L. Extract Enabled Mice to Overcome Insufficient Protection against Influenza A/PR/8 Virus Infection under Suboptimal Treatment with Oseltamivir.

    Science.gov (United States)

    Hong, Eun-Hye; Song, Jae-Hyoung; Shim, Aeri; Lee, Bo-Ra; Kwon, Bo-Eun; Song, Hyuk-Hwan; Kim, Yeon-Jeong; Chang, Sun-Young; Jeong, Hyeon Gun; Kim, Jong Geal; Seo, Sang-Uk; Kim, HyunPyo; Kwon, YongSoo; Ko, Hyun-Jeong

    2015-01-01

    Several anti-influenza drugs that reduce disease manifestation exist, and although these drugs provide clinical benefits in infected patients, their efficacy is limited by the emergence of drug-resistant influenza viruses. In the current study, we assessed the therapeutic strategy of enhancing the antiviral efficacy of an existing neuraminidase inhibitor, oseltamivir, by coadministering with the leaf extract from Hedera helix L, commonly known as ivy. Ivy extract has anti-inflammatory, antibacterial, antifungal, and antihelminthic properties. In the present study, we investigated its potential antiviral properties against influenza A/PR/8 (PR8) virus in a mouse model with suboptimal oseltamivir that mimics a poor clinical response to antiviral drug treatment. Suboptimal oseltamivir resulted in insufficient protection against PR8 infection. Oral administration of ivy extract with suboptimal oseltamivir increased the antiviral activity of oseltamivir. Ivy extract and its compounds, particularly hedrasaponin F, significantly reduced the cytopathic effect in PR8-infected A549 cells in the presence of oseltamivir. Compared with oseltamivir treatment alone, coadministration of the fraction of ivy extract that contained the highest proportion of hedrasaponin F with oseltamivir decreased pulmonary inflammation in PR8-infected mice. Inflammatory cytokines and chemokines, including tumor necrosis factor-alpha and chemokine (C-C motif) ligand 2, were reduced by treatment with oseltamivir and the fraction of ivy extract. Analysis of inflammatory cell infiltration in the bronchial alveolar of PR8-infected mice revealed that CD11b+Ly6G+ and CD11b+Ly6Cint cells were recruited after virus infection; coadministration of the ivy extract fraction with oseltamivir reduced infiltration of these inflammatory cells. In a model of suboptimal oseltamivir treatment, coadministration of ivy extract fraction that includes hedrasaponin F increased protection against PR8 infection that could be

  9. Coadministration of Hedera helix L. Extract Enabled Mice to Overcome Insufficient Protection against Influenza A/PR/8 Virus Infection under Suboptimal Treatment with Oseltamivir.

    Directory of Open Access Journals (Sweden)

    Eun-Hye Hong

    Full Text Available Several anti-influenza drugs that reduce disease manifestation exist, and although these drugs provide clinical benefits in infected patients, their efficacy is limited by the emergence of drug-resistant influenza viruses. In the current study, we assessed the therapeutic strategy of enhancing the antiviral efficacy of an existing neuraminidase inhibitor, oseltamivir, by coadministering with the leaf extract from Hedera helix L, commonly known as ivy. Ivy extract has anti-inflammatory, antibacterial, antifungal, and antihelminthic properties. In the present study, we investigated its potential antiviral properties against influenza A/PR/8 (PR8 virus in a mouse model with suboptimal oseltamivir that mimics a poor clinical response to antiviral drug treatment. Suboptimal oseltamivir resulted in insufficient protection against PR8 infection. Oral administration of ivy extract with suboptimal oseltamivir increased the antiviral activity of oseltamivir. Ivy extract and its compounds, particularly hedrasaponin F, significantly reduced the cytopathic effect in PR8-infected A549 cells in the presence of oseltamivir. Compared with oseltamivir treatment alone, coadministration of the fraction of ivy extract that contained the highest proportion of hedrasaponin F with oseltamivir decreased pulmonary inflammation in PR8-infected mice. Inflammatory cytokines and chemokines, including tumor necrosis factor-alpha and chemokine (C-C motif ligand 2, were reduced by treatment with oseltamivir and the fraction of ivy extract. Analysis of inflammatory cell infiltration in the bronchial alveolar of PR8-infected mice revealed that CD11b+Ly6G+ and CD11b+Ly6Cint cells were recruited after virus infection; coadministration of the ivy extract fraction with oseltamivir reduced infiltration of these inflammatory cells. In a model of suboptimal oseltamivir treatment, coadministration of ivy extract fraction that includes hedrasaponin F increased protection against PR8

  10. Première expérience de l'utilisation du Misoprostol comme soin après avortement (SAA) à Libreville, Gabon

    Science.gov (United States)

    Mayi-Tsonga, Sosthène; Minkobame, Ulysse; Mbila, Arielle; Assoumou, Pamphile; Diop, Ayisha; Winikoff, Beverly

    2014-01-01

    Introduction Une étude a été menée afin de déterminer le taux d'acceptabilité de 400µg de misoprostol par voie sublinguale comme traitement de première intention de l'avortement incomplet et de préciser le taux d'avortement complet ou vacuité utérine. Méthodes Les femmes éligibles avaient un diagnostic clinique d'avortement incomplet avec une taille utérine inférieure à celle d'un utérus de 12 semaines d'aménorrhées (SA). Chacune a reçu 400µg de misoprostol par voie sublinguale. Les femmes ont été revues après une semaine. A J7, celles qui n'avaient pas complètement expulsé ont eu le choix entre une nouvelle consultation de suivi à J14 et la pratique d'une évacuation chirurgicale immédiate. Résultats 145 patientes ont été éligibles et ont toutes accepté la méthode (100%). L’âge moyen était de 25,9 ± 6 ans. A J7, 120 patientes étaient guéries (85,7%). A J14, le taux de réussitea été de 95,7% soit 134 patientes guéries. Les patientes guéries ont déclaré être très satisfaites (57,5%), satisfaites (41,8%) et insatisfaite (0,7%). Au total,128 femmes (95,5%) ont dit être prêtes à utiliser de nouveau le misoprostol comme méthode d’évacuation utérine en cas d'avortement incomplet. Conclusion L’étude démontre que le 400µg misoprostol par voie sublinguale nous permet de prendre en charge d'une manière adéquate l'avortement incomplet surtout dans les pays à faible ressource et notamment dans les structures sanitaires de première ligne ou éloignées. PMID:25469194

  11. 冷战后法国外交政策的调整%La rénovation de la politique diplomatique en France aprés la Guerre froide

    Institute of Scientific and Technical Information of China (English)

    汪波

    2002-01-01

    Le gouvemement francais a rénové sa politique diplomatique après la guerre froide. Cette rénovation consiste à coopérer avec les Etats-Unis au sein de LOTAN, à participer d′avantage au proeessus de paix au Moyen-Orient et à exercer plus dinfluence sur lesaffaires africaines. Basée sur une reconnaissance du changement de la situation internationale, cette rénovation a pour objectif de consolider la position de la France au sein de la communauté internationale.

  12. L’exclusion des scientifiques allemands et de la langue allemande des congrès scientifiques internationaux après la Première Guerre mondiale

    OpenAIRE

    Reinbothe, Roswitha

    2013-01-01

    Après la Première Guerre mondiale les académies des sciences des pays alliés décidèrent de boycotter les scientifiques allemands et la langue allemande et fondèrent en même temps de nouvelles organisations scientifiques internationales : le Conseil international de recherches pour les sciences, qui chapeautait des unions internationales dans les disciplines les plus importantes, et l’Union académique internationale pour les sciences de l’homme. Les langues principales de ces organisations éta...

  13. L’aprenentatge de l’anglès a través de l’educació física: el programa ‘Mou-te i aprèn’ English language acquisition through physical education: the ‘Mou-te i aprèn’ programme El aprendizaje del inglés a través de la educación física: el programa ‘Mou-te i aprèn’

    Directory of Open Access Journals (Sweden)

    Josep Coral i Mateu

    2011-09-01

    Full Text Available L’objecte d’estudi d’aquest article és la relació entre l’educació física i l’aprenentatge de la llengua anglesa, per mitjà de l’enfocament educatiu AICLE (CLIL, en anglès, concretat en el programa Mou-te i aprèn. Pel que fa a l’educació física es fonamenta en la metodologia d’instrucció directa: global pura, anàlisi progressiu i anàlisi seqüencial, complementada amb estratègies d’aprenentatge cooperatiu. L’educació física és una forma diferent i excel·lent d’aprendre la llengua. La combinació de les diferents metodologies i tècniques són molt efectives per millorar alhora el llenguatge, la motricitat i la salut. ______________________________________________ L’objet d’étude de cet article est la relation entre ’éducation physique et l’apprentissage de la langue anglaise, grâce à la perspective éducative Content and Language Integrated Learning (CLIL, concrétisée dans le programme Mou-te i aprèn. En ce qui concerne l’éducation physique, elle est fondée sur la méthodologie d’instruction directe, globale, pure, d’analyse progressive et d’analyse séquentielle, complétée par des stratégies d’apprentissage coopératif. L’éducation physique est une manière différente et excellente d’apprendre la langue. La combinaison des différentes méthodologies et techniques est tout à fait effective pour améliorer la langue, la motricité de même que la santéThe aim of this article is to explore the relationship between physical education and learning the English language through the CLIL (Content and Language Integrated Learning approach, implemented through the Mou-te i aprèn [‘Move yourself and learn’] programme. With regard to physical education it is based on the methodology of direct instruction: pure global, progressive analysis and sequential analysis, supplemented with cooperative learning strategies. Physical education is a different, effective way to learn the

  14. Māsas rīcība pēcoperācijas brūču aprūpē ķirurģijas nodaļā

    OpenAIRE

    Spruntule, Inga

    2016-01-01

    Bakalaura darba tēma „Māsas rīcība pēcoperācijas brūču aprūpē ķirurģijas nodaļā” . Tēmas aktualitāti nosaka tas, ka ik dienu slimnīcās veic neskaitāmas operācijas un infekcija ir viena no komplikācijām pēcoperācijas periodā. Inficēšanās iemesli ir dažādi. Roku nemazgāšana ir viens no galvenajiem veidiem, kā izplatās infekcija slimnīcās. Ir aktuāli noskaidrot māsas rīcību pēcoperācijas brūču aprūpē, jo aseptikas un antiseptikas, roku mazgāšana un dezinfekcija, kā arī cimdu lietošana var mazi...

  15. Māsu izpratnes pilnveide par pacientu izglītošanu primārajā un sekundārajā veselības aprūpē

    OpenAIRE

    Fridrihsone, Baiba

    2016-01-01

    Pacientu izglītošana ir māsas pienākums, tomēr, māszinības programmās, kā arī veselības aprūpes iestādēs, pacientu izglītošana tiek veikta nepilnīgi vai netiek veikta nemaz. Problēmas risināšanai tika izvirzīts mērķis: izzināt kā pilnveidot māsu izpratni par pacientu izglītošanu primārajā un sekundārajā veselības aprūpē. Pētāmā grupa bija Latvijas Universitātes, Medicīnas fakultātes, profesionālās bakalaura studiju programmas (PBSP) “Māszinības” 4.kursa studenti, kuri pārstāvēja sešas māsu ap...

  16. L’abdication du Congrès après le 11 septembre : crise constitutionnelle ou politique ?

    Directory of Open Access Journals (Sweden)

    Maya KANDEL

    2011-09-01

    Full Text Available L’effondrement des tours jumelles de Manhattan le 11 septembre 2001 a renversé le rapport existant entre législatif et exécutif américains. Alors que certains avaient pu qualifier George W. Bush après son élection de « premier président post-impérial » face à un Congrès en pleine reconquête de ses prérogatives depuis la fin de la guerre froide, l’entrée des Etats-Unis dans la « guerre contre la terreur » a vu le retour d’une présidence impériale, et réduit les parlementaires à un rôle de quasi figuration. Historiquement, l’évolution semble attendue. Les phases d’extraversion de l’Amérique ont toujours correspondu à une affirmation de la prééminence présidentielle. Plus encore, en temps de crise et dès lors que la sécurité du peuple est en jeu, la prérogative constitutionnelle qui fait du président le commandant en chef des forces armées du pays lui donne une marge de manœuvre incomparable dans l’élaboration de la politique étrangère. Il était logique que le 11 septembre garantisse à Bush la victoire sur le Congrès dans la « compétition pour le privilège de conduire la politique étrangère du pays ». Les parlementaires se sont montrés particulièrement complaisants face à l’expansion des pouvoirs de l’exécutif, qu’ils ont souvent eux-mêmes autorisée – en particulier dans les mois qui ont suivi les attaques, puis par la suite, en raison de l’utilisation habile par Bush et le parti républicain d’une « politique de la peur » particulièrement efficace. Mais l’Administration Bush est allée beaucoup plus loin que cette simple logique. Par la pratique des signing statements, « déclarations de signature » ajoutées aux lois, le Président s’est accordé le droit d’interpréter, voire de choisir ou de corriger, certaines portions de la législation votée par le Congrès. Cette pratique n’a pas été inventée par Bush mais, qualitativement comme

  17. Confluences Méditerranée, n° 81, 2012/2, 236 p.Dossier : Algérie, 50 ans après

    OpenAIRE

    Mohammedi, Sidi Mohammed

    2015-01-01

    « L’Algérie fête cette année les 50 ans de son indépendance, une occasion pour revenir sur son parcours à la fois politique, économique et culturel. C’est l’objectif recherché par la revue Confluences Méditerranée à travers ce numéro consacré à « L’Algérie, 50 ans après » (p. 09). C’est ainsi qu’a ouvert Sid-Ahmed Souiah sa présentation en attirant l’attention que l’exhaustivité n’était pas recherchée pour choisir les thématiques retenues mais, plutôt, de présenter une variété de contribution...

  18. Valutazione dell'appropriatezza dei ricoveri in un Policlinico Universitario: analisi mediante l'uso comparativo dei sistemi di classificazione isogravitá APR-DRG e Disease Staging e del PRUO

    Directory of Open Access Journals (Sweden)

    M. Volpe

    2003-05-01

    Full Text Available

    Obiettivi: valutare l’appropriatezza organizzativa dei ricoveri effettuati in un Policlinico Universitario attraverso la comparazione di due metodi, dei quali uno basato sui dati della scheda di dimissione ospedaliera ed utilizza, rispettivamente, i sistemi di classificazione iso-gravità APR-DRG e Disease Staging e l’altro sulla revisione delle cartelle cliniche mediante il PRUO.

    Metodi: oggetto di analisi sono i ricoveri ordinari effettuati nell’anno 2001 ed afferenti ai DRG inclusi nella delibera della Giunta Regionale del Lazio 864/2002 che recepisce il D.P.C.M. 29/11/2001 sui livelli essenziali di assistenza.

    Risultati: i risultati evidenziano che le due varianti del
    metodo basato sulla SDO (metodo APPRO mostrano quote di ricoveri inappropriati sovrapponibili rispetto al complesso dei ricoveri oggetto di analisi, ma con differenze anche rilevanti tra APR-DRG e Disease Staging in relazione ai singoli DRG considerati, riconducibili ai diversi algoritmi di attribuzione del livello di severità utilizzati dai due sistemi. L’analisi campionaria effettuata con il metodo PRUO su casi afferenti ai DRG della DGR 864/2002 caratterizzati da livelli di severità minimi evidenzia una proporzione di ricoveri inappropriati superiore a quella determinata tramite i metodi basati sulla SDO. Tale differenza è verosimilmente dovuta al ruolo del valore delle soglie percentuali di accettabilità individuate dalla Regione Lazio per ciascun DRG: le quote di ricoveri che eccedono tali soglie sono considerate inappropriate.

    Conclusioni: sulla base dei risultati ottenuti gli autori
    descrivono gli interventi organizzativi adottati per ottimizzare il contesto di erogazione delle prestazioni
    oggetto di analisi, discutono vantaggi e limiti dei metodi SDO-based e del metodo analitico PRUObased e ne propongono l

  19. Application De Methodes Nucleaires Et Physico-chimiques D'analyse A L'etude, Apres Implantation, D'un Depot De Bioverre Sur Un Alliage De Titane, En Vue D'une Optimisation De La Biocompatibilite Et De La Fonctionnalite A Long Terme

    CERN Document Server

    Brun, V

    1999-01-01

    Application De Methodes Nucleaires Et Physico-chimiques D'analyse A L'etude, Apres Implantation, D'un Depot De Bioverre Sur Un Alliage De Titane, En Vue D'une Optimisation De La Biocompatibilite Et De La Fonctionnalite A Long Terme

  20. Tarifa e Ocupação em Hotéis: provocando o modelo de apreçamento convencional

    Directory of Open Access Journals (Sweden)

    Eder Paschoal Pinto

    2010-07-01

    -style:italic; mso-bidi-font-style:normal;} p.Captulo, li.Captulo, div.Captulo {mso-style-name:Capítulo; mso-style-unhide:no; margin-top:12.0pt; margin-right:0cm; margin-bottom:12.0pt; margin-left:0cm; text-align:justify; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Times New Roman","serif"; mso-fareast-font-family:"Times New Roman"; font-weight:bold; mso-bidi-font-weight:normal;} .MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; font-size:10.0pt; mso-ansi-font-size:10.0pt; mso-bidi-font-size:10.0pt;} @page WordSection1 {size:612.0pt 792.0pt; margin:70.85pt 3.0cm 70.85pt 3.0cm; mso-header-margin:36.0pt; mso-footer-margin:36.0pt; mso-paper-source:0;} div.WordSection1 {page:WordSection1;} -->

    Resumo

    O objetivo central deste trabalho é discutir a relação entre tarifa e taxa de ocupação em hotéis. As teorias de segmentação de clientes, composto mercadológico e estratégia de apreçamento foram aplicadas ao estudo. Os hotéis de Santos classificados como Turístico e Luxo foram escolhidos intencionalmente. Oitenta e três por cento deles responderam ao

  1. La chronologie du royaume de Qatabân du Ier siècle avant J.-C. au Ier siècle après J.-C.

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    Mounir Arbach

    2002-04-01

    Full Text Available Les nouvelles découvertes archéologiques et épigraphiques de ces dernières années, effectuées au cours des fouilles franco-italiennes à Tamna`, l'ancienne capitale du royaume de Qatabân, permettent d'établir une nouvelle chronologie des souverains de Qatabân entre le Ier siècle avant J.-C. et le Ier siècle après J.- C.The chronology of the kingdom of Qatabân, from the 1st century BC to the 1st century AD. Archaeological and epigraphical discoveries made in recent years by the Franco-Italian excavations at Tamna`, the ancient capital of the kingdom of Qatabân, allows us to establish a new chronology for the kings of Qatabân during the 1st century BC and the 1st century AD.

  2. Electrical, magnetic and magnetocaloric properties of polycrystalline Pr0.63A0.07Sr0.3MnO3 (A=Pr, Sm and Bi)

    Science.gov (United States)

    Elghoul, A.; Krichene, A.; Boujelben, W.

    2016-11-01

    We studied the effects of the partial substitution (10%) of praseodymium by samarium and bismuth, on the structural, magnetic, magnetocaloric and electrical properties of the Pr0.63A0.07Sr0.3MnO3 (A=Pr, Sm and Bi) manganites prepared using the solid state reaction. Refinement of the X-ray diffraction patterns shows that all our samples are single phase and crystallize in the orthorhombic structure with Pnma space group. Magnetic studies indicate that all the samples exhibit a ferromagnetic-paramagnetic transition with increasing temperature. Curie temperature TC decreases by substitution. M(H) curves indicate the presence of some antiferromagnetic domains in the substituted samples testifying the phase-separated nature of these samples. The magnetic entropy curves -ΔS(T) show a maximum in vicinity of TC. Important values of maximum of -ΔS are recorded for our compounds. For the parent compound, we found 4.59 J/kg K for an applied magnetic field of 2 T at TC=266 K which raises the possibility of using this compound as a magnetic refrigerant. The temperature dependence of the electrical resistivity ρ(T) indicates that all compounds exhibit a metal-insulator transition with increasing temperature. Electrical study suggests the presence of a correlation between electrical and magnetic properties.

  3. Aprèn història en anglès! Un projecte d’innovació de llengües estrangeres a l’Institut Julio Antonio de Móra d’Ebre

    Directory of Open Access Journals (Sweden)

    Loreto Meix-Boira

    2012-07-01

    Full Text Available Aprèn història en anglès! és un projecte d’innovació de llengües estrangeres creat per ensenyar història en anglès a estudiants de secundària la llengua materna dels quals no és l’anglès (CLIL, Content and Language Integrated Learning, també conegut com a AICLE, aprenentatge integrat de continguts i llengua estrangera . El projecte consta de tres blocs que tracten aspectes polítics, socials, econòmics i culturals sobre el món antic, Egipte i Roma, i l’edat mitjana (Life in Ancient Egypt, Ancient Rome i Middle Ages. Amb els materials creats per a aquest projecte, els estudiants tindran l’oportunitat de treballar amb textos atractius i amb una gran varietat d’activitats durant unes 140 hores. L’alumnat prendrà contacte amb les TIC (tecnologies de la informació i la comunicació, ja que part del material es troba a la xarxa i, a més, es tracta d’un projecte interdisciplinari, en el qual es treballen les ciències socials, l’anglès i les TIC. El material és adequat per utilitzar-lo amb alumnes de 12 a 15 anys.

  4. Les travaux de défense des châteaux delphinaux pendant la guerre de Cent Ans. Etude des réparations d'après les comptes de châtellenies au XIVe siècle

    OpenAIRE

    Nicolas, Nathalie

    2000-01-01

    International audience Cet article propose d'éclairer l'étude monumentale des châteaux delphinaux situés aujourd'hui dans le département des Hautes-Alpes d'après les réparations enregistrées par les châtelains du Dauphiné, dans leur comptabilité annuelle, en particulier au cours des années 1360 à 1400.

  5. Tēvu bērnības pieredze, depresijas un trauksmes simptomi perinatālajā periodā un to saistība ar viņu iesaistīšanos jaundzimušā aprūpē

    OpenAIRE

    Vedeņejeva, Veronika

    2016-01-01

    Maģistra darba pētījuma mērķis ir longitudināli izpētīt, kāda saistība pastāv starp vīrieša bērnības pieredzi un viņa iesaisti jaundzimušā bērna aprūpē, kā arī, vai topošo tēvu psiholoģiskais stāvoklis bērna perinatālajā periodā paredz viņa iesaistīšanos jaundzimušā aprūpē. Pie tam bija nozīmīgi izprast vīrieša psiholoģiskā stāvokļa dinamiku perinatālajā periodā, un vai izmaiņas psiholoģiskajā stāvoklī ir nozīmīgs faktors vīrieša iesaistei sava bērna aprūpē. Maģistra darba pētījums sastāvēja ...

  6. Emocionālās izdegšanas sindroms garīgās veselības aprūpē strādājošo māsu vidū

    OpenAIRE

    Cvetkovs, Andrejs

    2016-01-01

    Maģistra darba tēma – “Emocionālās izdegšanas sindroms garīgās veselības aprūpē strādājošo māsu vidū”. Pētījuma mērķis ir noskaidrot sakarības starp emocionālā intelekta līmeni un emocionālā izdegšanas sindroma attīstības pakāpi garīgās veselības aprūpē strādājošajām māsām. Saskaņā ar pētījuma tēmu tika izvirzīta hipotēze – pastāv sakarība starp garīgās veselības aprūpē strādājošo māsu emocionālā intelekta līmeni un emocionālās izdegšanas sindroma attīstības pakāpi. Lai sasniegtu pētījuma mē...

  7. Status quo der plastisch-rekonstruktiven Chirurgie aus der Sicht der Mund-, Kiefer- und Gesichtschirurgie

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    Heiland, Max

    2012-12-01

    Full Text Available The prior aim of facial plastic-reconstructive surgery was and will be the adequate restitution of appearance and function so that patients with trauma- or tumorassociated defects as well as congenital malformations can be successfully rehabilitated. Nowadays, three major techniques are used to achieve this goal: local flaps, pedicled flaps and microsurgical flaps. This overview article describes in detail the three major techniques of facial plastic reconstructive surgery from past to present and gives an outlook on upcoming new techniques like the virtual planning of reconstructive measures.

  8. State of the Art der plastisch-rekonstruktiven Chirurgie aus Sicht der Gynäkologie

    OpenAIRE

    Nestle-Krämling, Carolin

    2012-01-01

    In Germany plastic-reconstructive techniques are used in gynecology for aesthetic reasons as well as for correction of congenital malformations, reconstructive surgery or defect coverage after tumour resection in the genital area, in the abdominal region and in breast surgery. The evolution of plastic and reconstructive surgery in gynecology comprises the hole spectrum of allogenic and autologous techniques in the field of aesthetic and reconstructive surgery.

  9. Status quo der plastisch-rekonstruktiven Chirurgie aus Sicht der Viszeralchirurgie

    Directory of Open Access Journals (Sweden)

    Kröpil, Feride

    2013-12-01

    Full Text Available The Art of Surgery has a very long tradition and is one of the earliest treatments for serious injuries of diverse causes. Due to achievements in anesthesia and intensive care medicine in the second half of the nineteenth century, postoperative morbidity and mortality have been appreciably reduced. Operative techniques could be expanded and new operative therapies could be introduced. Although the last two-hundred years have brought about increasing specialization in medicine and operative specialties have developed in multiple areas, the operative spectrum of the visceral surgeon has remained rather broad and diverse. Numerous operative procedures are carried out in the entire gastroi tract as well as the body surface. Many of these are to treat diseases, while others are of help in the plastic reconstruction of organs and the body surface. Thanks to specialization, among the positive developments are shortened operation time and length of hospital stay, as well as reduced postoperative morbidity and mortality. The advances in minimal-invasive surgery and the progress in surgical instruments and suturing techniques are some origins of these positive developments. This article cannot cover all possible resections and reconstructions of the visceral surgeon, but will instead concentrate on two major sites. The operative treatment of inguinal hernias is one of the oldest operations known to humanity. Because hernias are one of the most common operations of all visceral surgical procedures, their surgical therapy shall be particularly highlighted here. But the plastic and reconstructive possibilities of the visceral surgeon are by no means limited to hernia repair. So this manuscript will further provide insight into the resection and reconstruction possibilities of the esophagus, one of the most challenging procedures in this field.

  10. Aktueller Stand der plastisch-rekonstruktiven Chirurgie aus der Sicht der Thoraxchirurgie

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    Rupprecht, Holger

    2012-12-01

    Full Text Available Bronchoplastic techniques: Plastic-reconstructive techniques in thoracic surgery have led to significant reductions of morbidity and mortality. Particulary the so-called sleeve resections are now commonplace in non-small cell carcinoma in stage I–IIIA, with rather similar five-year survival as conventional resections. Even with infiltration of large vessels (T4-stage, this technique can be applied even in the curative approach, e.g., replacement of the pulmonary artery by a vascular prosthesis (“double sleeve resection”.Extended resection of the anterior and lateral chest wall: Malignant tumors of the chest wall are caused by infiltration of the so-called T3-carcinoma of the lung, by primary bone tumors (e.g., chondrosarcoma or by osseous metastases from extrathoracic malignancies (e.g., breast cancer. After “en bloc-resection” of the chest wall including the surrounding lung parenchyma, the large defect is covered by a muscle rotation flap (M. latissimus dorsi. Sometimes these muscle flaps can not be used, for example in cachexia. In these cases, the bony thoracic defect is reconstructed by a Goretex-patch (Goretex Dualmesh. Then the patient undergoes laparotomy or laparoscopy and dissection of the omentum of the great curvature of the stomach while preserving the right epiploic artery. Through a subcutaneous tunnel, the omentum is displaced to the thoracic wall to cover the Goretex-patch. To accelerate the wound healing, the omentum is covered with a polyurethane sponge, which is pressed with a suction of 125 mm Hg (vacuum therapy. At about 4 weeks, the healed omentum can be covered with a split skin graft.Intrathoracic infections: Severe thoracic infections (empyema, lung abscess are usually caused by a pneumonia (80% or are the consequence of operative complications (e.g., bronchial stump insufficiency.The infection is not curable with the conventional irrigation drains. Often the muscle rotation flaps fail, too. The combination of the transposed greater omentum and polyurethane sponges (VAC leads to a faster cleaning of the soiled thoracic cavity and accelerates the wound granulation. With this technique, even unfavourable cases could be rehabilitated.Sternal wound infections: The osteomyelitis of the sternum is a potentially life-threatening complication (mediastinitis, especially after cardiac surgery. In these cases, the vacuum therapy (VAC with polyurethane sponges have contributed to the improved prognosis. Firstly, a more rapid debridement is provoked, and second the chest wall will be stabilized more quickly, because the VAC reduces the shear forces in a dehiscence of the sternum. After reaching clean conditions, a muscle flap or the greater omentum are interposed for final wound closure.

  11. Standortbestimmung – Status quo der plastisch-rekonstruktiven Chirurgie aus der Sicht der Handchirurgie

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    Koulaxouzidis, Georgios

    2012-12-01

    Full Text Available Modern plastic-reconstructive surgery, much like hand surgery, repres a young and fast-developing surgical discipline. The principles of plastic surgery originate in the developmental stages of surgery and have considerable influence on hand surgery. Microsurgery, free or pedicled transfer of tissue, peripheral nerve surgery, plexus surgery, tendon transfers, arthroplasty, vascularized bone transfers, or toe to thumb transplants, are all performed while considering plastic surgical principles and represent just a part of plastic surgical techniques which are daily applied in hand-surgical routine. They emphasize the intimate relationship and the mutual influence between the two disciplines. The future of plastic surgery is likely to include composite tissue allotransplantation, flap prefabrication, virtual surgical planning, application of growth factors to influence bone growth, fracture healing, angiogenesis, tendon healing or wound healing. Furthermore, the field of tissue engineering is likely to introduce novel materials, such as nerve conduits. All of the above may have direct influence on hand surgery and, therefore, the future of plastic and hand surgery is at least as intricately intertwined as was their past. They will remain related through the characteristics that led to their development: innovation, creativity, diversity and the search for individualized solutions.

  12. State of the Art der plastisch-rekonstruktiven Chirurgie aus Sicht der Gynäkologie

    Directory of Open Access Journals (Sweden)

    Nestle-Krämling, Carolin

    2012-12-01

    Full Text Available In Germany plastic-reconstructive techniques are used in gynecology for aesthetic reasons as well as for correction of congenital malformations, reconstructive surgery or defect coverage after tumour resection in the genital area, in the abdominal region and in breast surgery. The evolution of plastic and reconstructive surgery in gynecology comprises the hole spectrum of allogenic and autologous techniques in the field of aesthetic and reconstructive surgery.

  13. Tomographie par coherence optique pour le guidage de chirurgies minimalement invasives du rachis

    Science.gov (United States)

    Beaudette, Kathy

    Adolescent idiopathic scoliosis is a complex 3D deformity of the spine which requires surgical intervention in severe cases of the condition. The existing corrective procedure of scoliosis is very invasive; it involves a long incision and a large instrumentation, in addition to the fusion of a section of the spine. To improve postoperative conditions and to preserve patients' spinal flexibility, novel fusionless surgical approaches involving growth modulation are under investigation. With this objective in mind, a multidisciplinary team from École Polytechnique of Montreal and Sainte-Justine University Hospital Research Center is developing a surgical technique based on the insertion of micro-staples between vertebral growth plates and corresponding intervertebral disks. Each micro-staple passively modulates the vertebral growth on the convex side of the scoliotic curvature. This modulation modifies vertebral geometry which, for scoliotic patients, presents a wedging deformity. The modulation induced by these devices could lead to the correction of the curvature of the spine. This innovative procedure would preserve the flexibility of the spine as well as the health of intervertebral disks, in addition to being compatible with minimally invasive approaches. However, to be efficient, the micro-staples must be placed at the junction between the growth plate and the disk with a sub-millimeter precision. An intraoperative guiding system is therefore required to ensure the success of the intervention. Optical coherence tomography (OCT) is a promising candidate for this application. OCT is based on low-coherence interferometry and provides cross-sectional images with a resolution about 10 μm for a depth of 2 to 3 mm. This technique allows for the real-time acquisition of images and is compatible with endoscopy, thereby showing a potential for the intraoperative guidance of minimally invasive surgeries (MIS) of the spine. The main objective of this master's project is therefore to evaluate the possibility of using OCT to localize as well as identify spinal structures (such as growth plates, osseous tissue, intervertebral disks and connective tissue) and to guide the insertion of micro-staples. To attain this objective, an OCT handheld probe was designed and developed according to the surgical constraints of MIS performed by thoracoscopy (through the thorax). This probe has an external diameter of 17 mm and is 30 cm long. Coupled with a fibered interferometer, the axial and lateral resolutions of the probe are of 16 and 27 μm respectively. The OCT probe was used in vivo during an open surgery on a porcine model. Different tissues within the operative window (lung, muscles, osseous tissues and intervertebral disk) were imaged during the procedure. These preliminary in vivo tests demonstrated that the probe is capable of identifying different types of tissue with a good sensitivity and an adequate penetration depth. These results also showed that a visual inspection of the in vivo OCT images alone is not sufficient to localize the growth plates on the vertebrae. An ex vivo study using porcine vertebrae was therefore performed to identify quantitative markers in order to facilitate the interpretation of in vivo OCT images. OCT images were initially compared to corresponding histological sections. The ensuing results showed that the connective tissue layer presents a band pattern due to the birefringence properties of the collagen-rich tissue. The intervertebral disk was also shown to have a characteristic lamellar structure on OCT images. Lastly, within growth plate and osseous tissue locations, the OCT signal decay is monotonic, but with different attenuation coefficients (different slopes). Relative attenuation coefficients were therefore measured for each tissue (growth plate, osseous tissue, connective tissue and intervertebral disk) on several specimens and were compared. These results showed that growth plates present an average relative attenuation coefficient statistically different from the other tissues. An automatic growth plate segmentation algorithm was then developed and tested. The algorithm was applied to images from an ex vivo specimen of a porcine vertebra and successfully identified most of the growth plate (> 75%) amidst the osseous tissue of the vertebral body and the intervertebral disk. This master's project shows that OCT presents contrast, resolution and penetration depth that are sufficient for the identification of musculoskeletal structures of the spine. It is thus reasonable to believe that, ultimately, OCT could be used for the intraoperative guiding of the insertion of micro-staples during corrective surgeries of scoliosis.

  14. Tomographie par cohérence optique pour la chirurgie laser du glaucome

    OpenAIRE

    Bayleyegn, Masreshaw-Demelash

    2012-01-01

    The ability of optical coherence tomography (OCT) to deliver tomographic images of biological tissues in vivo non-invasively and in real-time has been a growing interest in many biomedical applications, mainly in ophthalmology for imaging the retina and the anterior segment of the eye. However, developing high-resolution OCT for imaging strongly scattering biological tissues like sclera and edematous cornea has still been the main challenge. In this PhD work, an ultrahigh-resolution (< 4 µm) ...

  15. Le CFEY et après…

    Directory of Open Access Journals (Sweden)

    François Burgat

    2000-09-01

    Full Text Available La livraison des Chroniques Yéménites 2000 s'inscrit dans le droit fil de l'initiative heureuse prise en 1993 par Frank Mermier, tout en prolongeant un effort entrepris dans la livraison précédente : allégées des comptes rendus de recherche cantonnés désormais au rapport scientifique du Centre et à son site Internet, les Chroniques entendent plus que jamais présenter un vaste panorama de la recherche sur le Yémen ou de la production intellectuelle de ce pays. La revue est désormais dotée d'un...

  16. Võistlused : [kalasport, 28. apr. - 30. juun. 2012

    Index Scriptorium Estoniae

    2012-01-01

    Kevadkalake, Töörahva Kala, Kevadsärg, Vagula Röövik, Saadjärve Haug, EMV Õngitsemises (mehed), Linnakala, Suure-Jaani Spinning, Tuulekala Trolling, Rakvere Koger, Gorodenko Spinning, EMV Õngitsemises (naised ja noored)

  17. Correlation of serum vascular endothelial growth factor levels with plasma,serum and P-APR in breast cancer%乳腺癌患者血管内皮生长因子水平与外周血各成分的相关性

    Institute of Scientific and Technical Information of China (English)

    罗琼; 陶霖玉

    2009-01-01

    Objective To look for a better way to assay vascular endothelial growth factor(VEGF) and explore the correlation of serum VEGF levels with platelet and leucocyte count in breast cancer by comparison of peripheral blood plasma, serum and P-APR. Methods Blood samples were obtained from 42 patients with breast cancer and 20 healthy volunteers. Serum, plasma and P-APR samples were analyzed for VEGF using a commercially available sandwich ELISA, and assayed for semiquantitative measurement using microplatereader. At the same time, samples were analyzed by hematology analyzer. Results The level of VEGF in peripheral blood positively correlated to platelet (health control group: r=0.424, P=0.063) and leucocyte (health control group: r=0.443, P=0.050). The difference in VEGF values of P-APR between the localized breast cancer group and the health control group was statistically significant. Conclusion The level of VEGF in peripheral blood positively correlates to platelet and leucocyte. Platelet and leucocyte possibly secrete VEGF in vitro. Compared with serum and plasma, P-APR is the best section assaying VEGF in peripheral blood.%目的 寻求血管内皮生长因子(VEGF)的最佳检测方法并探讨VEGF水平与血小板、白细胞数量之间的关系.方法 采集42例乳腺癌患者(乳腺癌组)及20例健康志愿者(对照组)外周静脉血,用VEGF单克隆抗体ELISA法分别测定血清、血浆、P-APR VEGF水平,经酶标仪半定量,同时血细胞分析仪计数血小板、白细胞数量.结果 血清VEGF水平与血小板数量呈正相关(r=0.424,P=0.063),血清VEGF水平与白细胞数量呈正相关(r=0.443,P=0.050).P-APR中的VEGF含量在局限性乳腺癌组与对照组间的差异有统计学意义(P=0.007).结论 外周血VEGF水平与血小板、白细胞呈线性相关,血小板、白细胞在外周血中可分泌VEGF;相对血清、血浆,P-APR是外周血中VEGF检测的最佳成分.

  18. Application de la méthode de Laue refocalisée à haute énergie à l'étude des mécanismes de recristallisation après déformation à froid de métaux CFC

    Science.gov (United States)

    Chauveau, Th.; Gerber, Ph.; Bastie, P.; Hamelin, B.; Tarasiuk, J.; Bacroix, B.

    2002-07-01

    In order to determine the kinetics of recystallization process, the Laue diffraction method is apllied here on cold rolled and recrystallized copper materials. Firts, the results obtained from reflexion X-ray diffraction texture measurements are presented. It is shown that the both techniques are complementar, and that the transmission Laue method presents some advantadges. Some previous hypotheses are verified in this work. Especially, the Cube orientation \\{100\\} loses during recrystallization its advantadge of growth, which implies the development of a mixed “deformed-recrystallized” texture at the end of the process. The nucleation step determines the final recrystallized texture. La méthode de Laue haute énergie est appliquée ici dans le but de déterminer les cinétiques de recristallisation de matériaux cuivre après laminages à froid et recuits interrompus. Après présentation des résultats obtenus par mesures classiques en réflexion, une comparaison est effectuée entre les deux techniques permettant de rendre compte des avantages certains qu'offrent des mesures en transmission et de la complémentarité des deux techniques utilisées. Quelques hypothèses sur les mécanismes régissant le processus de recristallisation sont ainsi vérifiées. Au tout début du processus de recristallisation, il a clairement été mis en évidence une perte de l'avantage de croissance des germes d'orientation Cube \\{100\\} au profit des composantes constituant la texture de déformation. Dans ce type de processus, n'est préférentielle que l'étape de germination, dans le sens où elle détermine la texture finale après recristallisation.

  19. Potentialités écologiques des carrières de quartzite après exploitation : l'exemple de la carrière de Cheffois (Vendée, France

    Directory of Open Access Journals (Sweden)

    François Bétard

    2011-06-01

    Full Text Available Dans les carrières de roches massives abandonnées après l'exploitation, l'aridité du sol et le caractère oligotrophe du milieu, conjugués à la présence de parois rocheuses et de plans d'eau au niveau des excavations les plus profondes, sont des éléments favorables à l'expression d'une biodiversité renouvelée et originale. Un inventaire écologique mené sur la carrière de quartzite de Cheffois, située dans le sud du Massif Armoricain, a révélé la richesse biologique de ce type de milieu semi-naturel. Les résultats de l'inventaire ont conduit à distinguer six types d'habitats néoformés correspondant à d'anciens secteurs d'exploitation : (1 un plan d'eau de fosse, (2 une zone de carreau humide, (3 une zone de carreau sec, (4 des fronts de taille d'expositions variées, (5 des remblais boisés, et (6 une galerie souterraine. Ces six types de milieux sont eux-mêmes subdivisés en une mosaïque de petits habitats, favorisant au final une grande biodiversité avec le développement de nombreuses espèces végétales et animales, dont certaines à forte valeur patrimoniale. Replacé dans le contexte du Bas-Bocage vendéen, l'apport écologique de la carrière de quartzite est évalué et confronté aux pertes en biodiversité engendrées par l'ouverture de la carrière. Avec les autres carrières de quartzite situées sur les sites rocheux des environs, elles constituent, ensemble, un réseau de carrières partiellement inondées pouvant contribuer à la création d'un véritable corridor écologique, dans une matrice bocagère actuellement en perte de biodiversité.In abandoned quarries of massive rocks, the aridity and oligotrophic character of soils, combined with the presence of rock walls and water bodies in the deeper excavations, are favourable to the expression of a renewed, original biodiversity. An ecological survey carried out on the quartzite quarry of Cheffois, located in the southern Armorican Massif, revealed the

  20. From après-ski to après-tourism: the Alps in transition?

    Directory of Open Access Journals (Sweden)

    Philippe Bourdeau

    2009-12-01

    Full Text Available Winter sports occupy a prominent place in European tourism, not only because of their economic importance in mountainous areas but also due to their major symbolic significance in the "leisure civilisation". Yet the world of winter tourism is full of uncertainties connected with climate change and also with evolutions and structural breaks that call into question the development model on which it is based. This context of profound change gives us the opportunity to question the limits of the industrial model that has governed the development of the Alps for the practice of skiing and to examine alternative future scenarios to "all-out skiing" and even "all-out tourism".Les sports d’hiver occupent une place de premier plan dans le tourisme européen, non seulement du fait de leur poids économique dans les régions de montagne, mais aussi par leur forte dimension symbolique dans la « civilisation des loisirs ». Pourtant l’univers du tourisme hivernal est parcouru par de nombreuses incertitudes liées au changement climatique, mais aussi à des évolutions et des ruptures structurelles qui remettent en question le modèle de développement sur lequel il repose. Ce contexte de mutation permet d’interroger les limites du modèle industriel qui a présidé à l’aménagement des Alpes pour la pratique du ski et d’examiner des figures d’avenir alternatives au « tout ski » et même au « tout tourisme ».

  1. Les réseaux sociaux et l’échange entre l’homme politique et les internautes : le cas de Facebook après les élections présidentielles en France Social Networks and the Exchange Between Politicians and Surfers: Facebook and the presidential post elections in France

    OpenAIRE

    Galia Yanoshevsky

    2010-01-01

    A travers l’analyse des interactions entre hommes politiques et internautes sur Facebook après les élections présidentielles de 2007 en France, cet article vise à montrer comment les réseaux sociaux sont exploités par les deux parties. Au départ un réseau décentralisé qui lie les gens sans intervention politico-hiérarchique, Facebook est mobilisé par les hommes politiques au service de leur besoins. Quelles en sont les conséquences pour la sphère publique : s’agit-il d’un outil qui permet à l...

  2. reconstruction de formes pour la chirurgie assistée par ordinateur basée sur l'enregistrement

    OpenAIRE

    Fleute, Markus

    2001-01-01

    L'objectif de cette thèse est la reconstruction de surfaces anatomiques à partir d'un nombre restreint de radiographies et de points acquis en phase per-operatoire. L'approche proposée repose sur une mise en correspondance des données avec un modèle déformable statistique afin d'incorporer de la connaissance à priori sur la forme de l'objet à reconstruire. L'élaboration d'un tel modèle statistique nécessite l'analyse de forme dans une population donnée. Pour cette analyse un modèle générique ...

  3. Die Gefäßarchitektur der Bauchwand und ihre Stellung in der Plastischen Chirurgie : eine anatomische Untersuchung

    OpenAIRE

    Okafor, Chukwubikem Akabogu

    2008-01-01

    Background and Aim: Wound healing complications and / or necrosis of the umbilicus, due to decreased vascularisation as a result of plastic surgical interventions as in abdominoplasty or abdominal flap surgery e.g. TRAM-flaps, VRAM-flaps, DIEP-flaps and SIEA-flaps are frequent. Aim of this study is to define territories of the abdominal wall which run the risk of decreased vascularisation in order to optimise plastic surgical techniques.Methods: Twelve fresh and unfixed human corpes of either...

  4. Optimisation of radio-guided interventional procedures in vascular surgery; Optimisation des procedures interventionnelles radioguidees en chirurgie vasculaire

    Energy Technology Data Exchange (ETDEWEB)

    Sabatier, Jean [Service de chirurgie vasculaire, Clinique de l' Europe, 73 Boulevard de l' Europe, 76100 Rouen (France)

    2011-07-15

    Vascular surgery has evolved in the past twenty-five years, with the appearance of endovascular techniques which are assuming an increasingly important place in the therapeutic arsenal against peripheral vascular pathologies. These techniques require the use of an X-ray image intensifier (XRII) which exposes the medical personnel, ancillary staff and patient to ionising radiation. The most common arterial damage that can be treated by endovascular techniques concern the thoracic aorta, the abdominal aorta, the visceral arteries, the arteries to the brain, the arteries of the upper and lower limbs. These interventions take place in operating theaters in a surgical environment with the use of a mobile XRII ring and a radiation-transparent carbon surgical table. The radiation protection of the staff and the patient is in any case based, whenever possible, on the use of pulsed techniques, diaphragms, and the wearing of protective aprons and goggles. Depending on the part of the body and the damage being treated, the irradiation dose will be extremely variable. (author)

  5. Mise en place de sc\\'enarios pour la conception d'outils en Chirurgie Minimalement Invasive

    CERN Document Server

    Thomann, Guillaume; Verdier, Morgan; Meillon, Brigitte

    2007-01-01

    Nowadays, more and more surgical interventions are carried out in Minimally Invasive Surgery, to make the post-operative constraints less painful for the patient. Actually, new surgical tools or medical products are designed after informal discussions between surgeons and designers. The user requirements documents are the main document used by the mechanical designers to design and improve the product. Medical terms, often used by surgeons and employed to explain their needs, don't allow for an instantaneous understanding by designers. Unfortunately, this relation causes a dysfunction in the definition cycle of the product. Our aim is to work on the design process, its assistance thanks to methods and tools and on its organisation for better understandings and more complementarities between surgeons and designers. We propose on this article a design method already tested in the informatics domain: User Centred Design which takes the user into account more effectively in the process design. We already propose ...

  6. Registrierung von 3D-Ultraschall mit MRT- und CT-Daten für die navigierte Chirurgie

    OpenAIRE

    Dekomien, Claudia

    2013-01-01

    Das in dieser Arbeit vorgestellte ultraschallbasierte Navigationssystemen basiert auf der Registrierung von präoperativen MRT- oder CT-Volumendaten mit dem intraoperativen 3D-Ultraschall. Für die Registrierung des intraoperativen Ultraschall mit den präoperativen Bilddaten wird ein Oberflächen-Volumen-Algorithmus verwendet. Im Rahmen dieser Arbeit wurden die in Vorarbeiten entwickelte ultraschallbasierte Registrierung wie folgt erweitert: Erweiterung auf die Registrierung von MRT-...

  7. Lung cancer from the perspective of internal medicine and surgery; Lungenkrebs aus Sicht der Inneren Medizin und Chirurgie

    Energy Technology Data Exchange (ETDEWEB)

    Prasse, A.; Mueller-Quernheim, J. [Universitaetsklinikum Freiburg, Abteilung fuer Pneumologie, Medizinische Klinik, Freiburg (Germany); Waller, C. [Universitaetsklinikum Freiburg, Abteilung fuer Haematologie und Onkologie, Medizinische Klinik, Freiburg (Germany); Passlick, B. [Universitaetsklinikum Freiburg, Abteilung fuer Thoraxchirurgie, Chirurgische Klinik, Freiburg (Germany)

    2010-08-15

    In previous years numerous advances in diagnostics, staging and therapy of lung cancer have been achieved. Nevertheless, it remains the most frequent cause of death from cancerous diseases. Early diagnosis and exact staging enable multimodal therapy regimens adjusted to age and comorbidities, which result in complete remission in a few and in prolonged survival and good quality of life in most patients. Curative surgery is possible in stage I non-small cell lung cancer (NSCLC) and results in a 5-year survival rates of up to approximately 75%. Using multimodal therapy approaches long-term survival can even be achieved in 40-50% of patients with advanced T4 tumors. However, in NSCLC with distant metastases median survival time is only 8-12 months. In elderly patients with no surgical options low cytotoxic monotherapy can be employed with a palliative intent. In the limited disease stage of small cell lung cancer (SCLC) long lasting remission after polychemotherapy has been observed in a minority of patients. However, in the extensive disease stage polychemotherapy prolongs the survival time of SCLC patients from 1-2 months to approximately 12 months. (orig.) [German] In den zurueckliegenden Jahren hat es bzgl. Diagnostik, Stadieneinteilung und Therapie des Lungenkarzinoms einige Fortschritte gegeben. Dennoch ist es weiterhin die haeufigste Todesursache durch Krebserkrankungen. Eine zuegige Diagnostik, gefolgt von einer exakten Stadieneinteilung, erlauben multimodale Therapieansaetze, die an Lebensalter und Komorbiditaeten angepasst werden koennen. Kurative Operationen sind im Stadium I des nichtkleinzelligen Lungenkarzinoms (NSCLC) moeglich und fuehren zu einem 5-Jahres-Ueberleben von bis zu 75% aber auch bei fortgeschrittenen T4-Tumoren kann durch eine multimodale Therapie noch ein Langzeitueberleben von 40-50% erreicht werden. Beim nichtkleinzelligen Lungenkarzinom mit Fernmetastasen betraegt die mediane Ueberlebenszeit jedoch nur noch 8-12 Monate. Insgesamt fuehren die aktuell verfuegbaren multimodalen Therapien bei den meisten Patienten zu einer Lebensverlaengerung mit guter Lebensqualitaet. Zur Palliation kommen bei inoperablen Patienten in hohem Alter Monochemotherapien mit nur geringer Toxizitaet zum Einsatz. Beim kleinzelligem Lungenkarzinom im Stadium ''limited disease'' werden gelegentlich langfristige Remission nach Polychemotherapie beobachtet. Im Stadium ''extensive disease'' verlaengert diese die Lebenserwartung von 1-2 auf etwa 12 Monate. (orig.)

  8. Modifications de l'expression des gènes GST-μ et p53 dans des lignées tumorales cellulaires humaines O.R.L. après irradiation gamma : induction, études cellulaires et moléculaires

    Science.gov (United States)

    Dubessy, C.; Merlin, J. L.; Marchal, C.

    1998-04-01

    Cell sub-populations surviving to high radiation doses were selected. The KBm survival part was obtained by exposure to a mutagenic agent and irradiation, FaDum results of a progressive irradiation of FaDu. A semi-quantitative RT-PCR analysis revealed a significant overexpression of GST-μ and p53 genes for KBm and FaDum cell lines that remained stable for 18 months. The SF2, α, β, and MID parameters, determined by clonogenic assays, show no modifications of radiosensitivity. The variations of expression observed are not correlated to a radiosensitivity variation. The overexpression of GST-μ and p53 does not seem to be a radiosensitivity marker. Nous avons isolé des sous-populations de 2 lignées cellulaires humaines (KB et FaDu) de carcinomes des voies aéro-digestives supérieures survivant à de fortes doses d'irradiation. La fraction survivante KBm a été obtenu après exposition à un agent mutagène et à une irradiation, FaDum résulte de l'irradiation progressive de FaDu. Une analyse par RT-PCR semi-quantitative nous a permis de mettre en évidence une surexpression significative des gènes GST-μ et p53 pour les souches KBm et FaDum analysées après 18 mois de culture. Les paramètres, α, β, SF2, MID, déterminés par essais clonogéniques, n'indiquent pas de modification de la radiosensibilité. Les variations d'expression observées ne sont donc pas corrélées à une variation de radiosensibilité. La surexpression des gènes GST-μ et p53 ne semble pas constituer un marqueur de radiosensibilité.

  9. Les réseaux sociaux et l’échange entre l’homme politique et les internautes : le cas de Facebook après les élections présidentielles en France Social Networks and the Exchange Between Politicians and Surfers: Facebook and the presidential post elections in France

    Directory of Open Access Journals (Sweden)

    Galia Yanoshevsky

    2010-10-01

    Full Text Available A travers l’analyse des interactions entre hommes politiques et internautes sur Facebook après les élections présidentielles de 2007 en France, cet article vise à montrer comment les réseaux sociaux sont exploités par les deux parties. Au départ un réseau décentralisé qui lie les gens sans intervention politico-hiérarchique, Facebook est mobilisé par les hommes politiques au service de leur besoins. Quelles en sont les conséquences pour la sphère publique : s’agit-il d’un outil qui permet à l’internaute de déjouer les usages de marketing politique qu’en fait l’homme politique ?The purpose of this article is to show how social networks, and more specifically Facebook, are used by politicians and their supporters. This is achieved through a detailed analysis of exchange of posts between politicians and surfers in the period following the presidential election campaigns in France of 2007. It is shown how politicians take advantage of Facebook, despite its initially being a decentralized social network, connecting people without a political or hierarchic purpose. The article attempts to show some of the consequences of such an exploitation of a public network for the public sphere and asks how much leverage there is for the surfers/citizens in moderating political marketing on Facebook.

  10. 15 CFR 740.16 - Additional permissive reexports (APR).

    Science.gov (United States)

    2010-01-01

    ... among: Albania, Australia, Austria, Belgium, Bulgaria, Canada, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Japan, Latvia,...

  11. Chernobyl, after the apocalypse; Tchernobyl, apres l'apocalypse

    Energy Technology Data Exchange (ETDEWEB)

    Coumarianos, Ph

    2000-07-01

    This document recalls the human aspects of the Tchernobyl reactor accident threw a series of testimonies, from the power plant head and engineers, to the firemen and people from the surrounding population. (J.S.)

  12. Chernobyl, 13 years after; Tchernobyl, 13 ans apres

    Energy Technology Data Exchange (ETDEWEB)

    Regniault-Lacharme, Mireille; Metivier, Henri [Inst. de Protection et de Surete Nucleaire, CEA Centre d' Etudes de Fontenay-aux-Roses, 92 (France)

    1999-04-01

    This is an annual report, regularly issued by IPSN, that presents the ecological and health consequences of the Chernobyl Nuclear Accident. The present status of the Chernobyl Nuclear Plant, which Ukraine engaged to stop definitively in year 2000, is summarized. The only reactor unit now in operation is Chernobylsk-3 Reactor which poses two safety questions: evolution of cracks in part of the tubing and behaviour of the pressure tubes. Although, some improvements in the RBMK reactor types were introduced, problems remain that make IPSN to stress the requirement of stopping this NPP completely. In the contaminated territories surrounding Chernobyl incidence rate of infant thyroid cancers continues to grow, reaching values 10 to 100 times higher than the natural rate. In France the IPSN analyzed 60,000 records carried out in 17 sites during May 1986 and April 1989. It was estimated that the individual dose received during 60 years (1986-2046) by the inhabitants of the most affected zone (eastern France) is lower than 1.5 mSv, a value lower than 1% of the natural cosmic and telluric radioactivity exposure for the same period. For the persons assumed to live in the most attacked forests (from eastern France) and nourishing daily with venison and mushrooms the highest estimate is 1 mSv a year. Concerning the 'hot spots', identified in mountains by IPSN and CRIIRAD, the doses received by excursionists are around 0.015 mSv. For an average inhabitant of the country the dose piled up in the thyroid due to iodine-131 fallout is estimated to 0.5-2 mSv for an adult and 6.5-16 mSv for an infant. These doses are 100 to 1000 times lower than the ones to which the infants living in the neighbourhood of Chernobyl are exposed to. The contents of the report is displayed in the following six chapters: 1. Chernobyl in some figures; 2. The 'sarcophagus' and the reactors of the Chernobyl NPP; 3. Health consequences of the Chernobyl accident;. 4. The impact of Chernobyl fallout in France; 5. Chernobyl's environment and the management of contaminated territories.; 6. The French-German initiative for Chernobyl.

  13. Chernobyl, 14 years later; Tchernobyl, 14 ans apres

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report draws an account of the consequences of Chernobyl accident 14 years after the disaster. It is made up of 8 chapters whose titles are: (1) Some figures about Chernobyl accident, (2) Chernobyl nuclear power plant, (3)Sanitary consequences of Chernobyl accident, (4) The management of contaminated lands, (5) The impact in France of Chernobyl fallout, (6) International cooperation, (7) More information about Chernobyl and (8) Glossary.

  14. Chernobyl, 12 years later; Tchernobyl, douze ans apres

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-04-01

    This report draws an account of the consequences of Chernobyl accident 12 years after the disaster. It is made up of 7 chapters whose titles are: (1) Some figures about Chernobyl accident, (2) The Chernobyl nuclear power plant, (3) Sanitary consequences of Chernobyl accident, (4) The management of contaminated lands, (5) The impact in France of Chernobyl fallout, (6) The Franco-German cooperation, and (7) Glossary.

  15. Acid Rain Data at Yokohama, Japan (Apr. 2003-Aug. 2004)

    OpenAIRE

    Murayama, Haruta

    2005-01-01

    Rain samples were collected adequately at the center of Yokohama city from April 2003 to August 2004. Total numbers of samples were 214. pH values and electric conductivity (E.G.) were measured immediately after catched samples and then chemical species were analyzed. This report is contained all observed data. Frequency of acid rain(pH

  16. ABSTRACTS( Vol. 26 No. 2 Apr. 2012)

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Fa Lin, Wang Lei, Zheng Yajuan, Zhang Qi and Zhang Xiaohu. The application of acoustics in oil logging and geophysical exploration. PI. 2012,26 (2): 1-6 By using the method of acoustic-electric analogue, this paper sets up the equivalent circuits of acoustic transducer, and gives the relationship between the acoustic-signal radiated by the source-transducer and the driving-voltage signal and that between the acoustic-signal and electric-signal converted from the receiver-transducer. This paper employs the convolution of the driving-voltage signal with the electric-acoustic impulse response of the source-transducer to replace some assumed acoustic-source functions adopted in previouly published literature on acoustic logging, such as Tsang wavelet and so on. In this paper the concept and theory of signal transmission is used to analyze the total acoustic- logging process, and the acoustic-logging transmission network model is set up. This model sets up the theoretical basis for accurate measurements of propagation speed, phase, amplitude and frequency information of acoustic-logging signal. The development of a new device, Kaiser in-situ stress system is introduced. This device is designed to measure in-situ stresses via detected acoustic emissions caused by the Kaiser effect in rocks. The system provides a technical means for both the economic and efficient evaluation of the three principal stresses in rocks. This is useful to assess the in-situ stress field in oil and gas reservoirs and to predict natural geology hazard. A new algorithm of inversion oil reservoir by using logging data and seismic exploration date is also described.

  17. Zorn: Avant/Après/Passé

    Directory of Open Access Journals (Sweden)

    John Lowell Brackett

    2012-06-01

    Full Text Available Witold Wachowski’s brief exchange with John Zorn provides us with many valuable insights relating to the composer’s aesthetic. Zorn’s professed antipathy towards audiences, his faith in the creative instinct of the “artist,” and his belief in the transcendental nature of musical works (as a gateway into a world of “truth” and “beauty” are all refrains commonly encountered in many interviews with the composer. Given the fact that Zorn emphasizes these themes in his very short interview with Wachowski, we can assume that these ideas form the core of Zorn’s musical and artistic aesthetic. For any person with even a basic knowledge of Western aesthetic traditions, however, these same aesthetic features and positions characterize musical institutions common to the Western art tradition, particularly the “romantic” ideal of music and composers that developed in the nineteenth century. Philosophers (most notably Hegel and Kant along with music critics and composers (such as Friedrich Schiller, E.T.A. Hoffmann, Friedrich Schlegel, Robert Schumann, and Eduard Hanslick all contributed to the development of a romantic musical aesthetic in the nineteenth century that emphasized the role of the artist (as a “genius” or “god-like” who created “works” that – through purely musical relations that exist irregardless of the listener’s abilities – reveal hidden worlds of truth and beauty, worlds far-removed from the humdrum concerns of daily existence. Given the close (nearly one-to-one correspondences between Zorn and aestheticians/philosophers of the nineteenth century, one could make the argument that Zorn holds a “romantic” view of music and art.

  18. Two years after the storms; 2 ans apres les tempetes

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-12-01

    This document takes stock on the power distribution repair, two years after the storms of december 1999 in France. It also presents the new organization (FIRE) developed to face such natural or accidental disasters. (A.L.B.)

  19. To rehabilitate life after Tchernobyl..; Rehabiliter la vie apres Tchernobyl..

    Energy Technology Data Exchange (ETDEWEB)

    Paillard, B.; Pena-Vega, A. [Centre d' Etudes Transdisciplinaires, Sociologie, Anthropologie, Histoire, EHESS, 75 - Paris (France)

    2003-09-01

    This article is a survey of the difficult daily life of the people living in a small town 70 km away from Chernobyl. The local authorities have to cope with first, the global aging of the population due to the massive departure of young families in 1991 when the first cases of thyroid cancers broke out and secondly, the arrival of very poor people that settled in the abandoned accommodations. The preventive measures taken to limit the internal contamination of the inhabitants are difficult to implement and maintain because of the invisibility of radioactivity, the flourishing surrounding nature, time passing and the lack of danger awareness of the new inhabitants. The poor standard of population health is due to aging (cancers and cardiovascular diseases), to the impact of radioactive contamination (thyroid cancer among the young) but is aggravated by the very low standard of living (tuberculosis is spreading). The local economy collapsed when 50% of the land were banned from any farming activity because of the radioactive contamination, another important resource was the forest but today a large part of wood is unfit for being sold or used as firewood. On the other hand the management of contaminated areas has driven up the production costs. (A.C.)

  20. La sociologie des usages, et après ?

    OpenAIRE

    Proulx, Serge

    2015-01-01

    Les interrogations traversant cet article peuvent se formuler ainsi : comment les études d’usage ont-elles évolué depuis 1980 ? Peut-on y repérer des moments de rupture ? Et que nous apprennent les courants voisins – surtout anglo-saxons et restés largement méconnus pendant la première décennie de réalisation des recherches françaises – notamment en ergonomie, en interactions humains-machines et plus tard, en « collaboratique » de même qu’en ethnographie du travail humain, sur le rôle attribu...

  1. Market Review RE Market Apr.10~20

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ RE carbonate in Baotou was in tight supply due to the strong demand.Prices of Nd and Pr products kept on rising recently.Affected by the price rising of SmEuGd concentrate in Baotou,price of europium went upward.

  2. Extended Station Blackout Coping Capabilities of APR1400

    OpenAIRE

    Sang-Won Lee; Tae Hyub Hong; Mi-Ro Seo; Young-Seung Lee; Hyeong-Taek Kim

    2014-01-01

    The Fukushima Dai-ichi nuclear power plant accident shows that an extreme natural disaster can prevent the proper restoration of electric power for several days, so-called extended SBO. In Korea, the government and industry performed comprehensive special safety inspections on all domestic nuclear power plants against beyond design bases external events. One of the safety improvement action items related to the extended SBO is installation of external water injection provision and equipment t...

  3. Apres nous, le déluge / Toomas Hendrik Ilves

    Index Scriptorium Estoniae

    Ilves, Toomas Hendrik, 1953-

    2005-01-01

    Autor mõtiskleb Euroopa Parlamendi liikmena selle üle, mida Euroopa viimase kuu sündmused tähendavad ja endaga kaasa toovad. Põhiseadusliku leppe läbikukkumine, vanade liikmesriikide suhtumine uutesse, Venemaa mõju väikestele Ida-Euroopa riikidele, soovitused Eestile edasiseks käitumiseks

  4. Chernobyl, fifteen years after; Tchernobyl, 15 ans apres

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-04-01

    This work has been constituted around four questions: the future of the Chernobyl site, the damaged reactor, and the sarcophagus around it; the health consequences of the accident on the persons that have worked on the damaged reactor and on the population in the countries the most exposed to fallout,; the situation of contaminated territories around the power plant and their management today; the last question concerns especially the France with the consequences of the radioactive cloud and what we know about the health risks induced by this event. (N.C.)

  5. Chernobyl, 16 years later; Tchernobyl, 16 ans apres

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-04-01

    This document on the Chernobyl site evolution is constituted around four main questions. What about the future of the Chernobyl site, the damaged reactor and the ''sarcophagus'' constructed around the reactor? What about the sanitary consequences of the accident on the liquidators asked to blot out the radiation and the around people exposed to radiation? What about the contaminated land around the power plant and their management? Concerning the France, what were the ''radioactive cloud'' sanitary consequences? (A.L.B.)

  6. La politique française à l’égard de l’émigration juive polonaise de l’immédiat après-guerre French policy towards the Exodus of Polish Jews in the Aftermath of World War II

    Directory of Open Access Journals (Sweden)

    Julia Maspero

    2012-03-01

    Full Text Available Cet article traite de la politique française à l’égard de l’émigration juive polonaise de l’immédiat après-guerre. Cette politique se définit en France et dans les zones françaises d’occupation en Allemagne et en Autriche. Comme le montre l’existence d’une catégorie « DP juifs » dans les recensements ainsi que la mise en place de camps DP juifs et de kibboutzim, les autorités françaises considéraient les réfugiés juifs de l’Est comme un groupe à part. Cet article montre le rôle important, pour atteindre la France et l’Italie puis la Palestine, joué par les zones françaises d’occupation de part leur position géographique cruciale (relations diplomatiques avec les Américains et Italiens, politique de refoulement…. La France a quant à elle été pour ces réfugiés bien plus un pays de transit vers les Amériques et la Palestine qu’un pays d’accueil, comme on peut le constater à travers les tentatives de contrôle des flux : mise en place d’un accord sur l’admission en transit de 8 000 réfugiés juifs de Pologne (conditions de l’accord, position des différents ministères français et des organisations juives en France… et refoulement vers l’Allemagne.This article is about the French policy towards Polish Jews emigration in the aftermath of WWII. This policy has been defined in France and in French zones of occupation in Germany and Austria. As shown by the existence of a “Jewish DPs” category in the census and the setting up of Jewish DP camps and kibbutzim, French authorities considered Jewish refugees from Eastern Europe as a separate group. This article shows the important role played by the French zones in the path followed by Jewish refugees in order to reach France and Italy and then Palestine (diplomatic relations with Americans and Italians, the policy of expulsion. It also shows that France has been for these refugees more a transit country to Americas and Palestine than

  7. Epidemiological analysis on virus etiology of acute respiratory infection during Oct 2010 and Apr 2011 in Beijing%北京地区2010年10月至2011年4月急性呼吸道感染病毒流行特征分析

    Institute of Scientific and Technical Information of China (English)

    黄芳; 石伟先; 崔淑娟; 钱海坤; Yan Li; 邓瑛

    2011-01-01

    spectrum were influenza A virus, respiratory syncytial virus and adenovirus. The positive ratio for the virus detection was distributed timely. It was high from Oct to Apr of next year and it as maximum in Nov (93.75%) while it was dropped down from Mar. The dominated viruses were different in different months and in different age groups. For the 0 ~ 5 age groups, the respiratory syncytial virus was maximum and for 5 ~ 15 age group adenovirus was found largest while for all the other age groups more than 15 years old influenza A was the dominated virus. Conclusions Influenza virus, respiratory syncytial virus, adenovirus were the main pathogens leading to acute respiratory infection during winter and spring in Beijing and the pathogens have specific epidemiology according to the ages and months.

  8. Chirurgie virtuelle : modélisation temps réel des tissus mous, interactions et système haptique dédié

    OpenAIRE

    Chendeb, Safwan

    2007-01-01

    The medical field is emerging recently some pedagogic simulators like what it exists from several years in other field like flight simulator or car driving simulator. Indeed, the current training of surgeons is performed on corpses (difficult, expensive and not practical) and companionship (with experienced surgeons). These difficulties involve a growing demand for surgical pedagogic simulators, especially in the field of mini-invasive surgery, with a consideration of gestures and tactile sen...

  9. Korrelation der bioelektrischen Impedanz-Analyse (BIA) und Lebensqualität nach körperformenden Eingriffen in der Plastischen Chirurgie

    OpenAIRE

    Smeets, Ralf

    2003-01-01

    Introduction: In plastic surgery, body contouring becomes more popular. In this study, long-term effects of abdominoplasty and liposuction on fat-/BMI-values and changes in quality of life were analysed. Materials and methods: The study included two patient groups who underwent plastic surgery between October 1998 and November 2001. 57 patients (group A) underwent liposuction, 41 (group B) abdominoplasty. Fat and BMI-values were determined one hour before surgery, at the first postoperative d...

  10. Place of surgery in high-risk tumours of the prostate; Place de la chirurgie dans les tumeurs de la prostate a haut risque

    Energy Technology Data Exchange (ETDEWEB)

    Soulie, M. [Service d' urologie, d' andrologie et de transplantation renale, hopital de Rangueil, CHU de Toulouse, 31 - Toulouse (France); Universite Paul-Sabatier, 31 - Toulouse (France); Rozet, F. [Service d' urologie, institut Montsouris, 75 - Paris (France); Universite Descartes-Paris 5, 75 - Paris (France); Hennequin, C. [Service de radiotherapie, hopital Saint-Louis, 75 - Paris (France); Universite Paris-Diderot Paris-7, 75 - Paris (France); Salomon, L. [Service d' urologie, hopital Henri-Mondor, 94 - Creteil (France); Universite Paris-Est Creteil Val-de-Marne, 94 - Creteil (France)

    2010-10-15

    Among the different options recommended for high-risk prostate cancer, radical prostatectomy is admitted as radiotherapy, but its role is still controversial in mono-therapy and difficult to evaluate in combined treatments. The results of clinical trials combining an external radiotherapy to a long-term androgen deprivation in locally advanced tumours sustain the principle of a multidisciplinary management in high-risk prostate cancer. The impact of surgery on the risk of progression and local recurrence is important in selected patients with low grade and small tumoral volume. Clinical and histological data associated to the MRI assessment remain essential and enhance the preoperative multidisciplinary decision, especially regarding nodal and distant metastases. Radical prostatectomy with an extended pelvic lymphadenectomy can be considered as a viable alternative to radiotherapy and hormonal therapy in these patients with a long life expectancy but presenting a high risk of local progression and a low risk of metastatic disease. Morbidity of the procedure is similar to radical prostatectomy for organ-confined tumours despite more erectile dysfunction due to non-sparing radical prostatectomy in most of cases. Oncological results from recent compiled series show 10- and 15-year specific survival rates around 85 and 75%, respectively, including adjuvant or salvage treatments with radiotherapy, androgen deprivation or chemotherapy. (authors)

  11. COMENTARIU LA ARTICOLUL FISTULE CHOLÉCYSTO - DUODÉNALE E. Christide - Revista de Chirurgie 1938; 7 - 8/41: 579 - 585

    OpenAIRE

    Nicolae M. Constantinescu

    2012-01-01

    Prezenţa unei fistule colecisto-duodenale este încă şi astăzi de cele maimulte ori o descoperire intraoperatorie. Deşifrecvenţa acestei complicaţii a bolii litiaziceeste relativ redusă (în jur de 2% dupăGlenn[1]ea ar trebui să beneficieze de undiagnostic preoperator mai mare decât celactualcare nu depăşeşte 1/6 bolnavi [2], şiaceasta datorită mortalităţii postoperatorii de15-22%, mult superioară celei înregistrateînabsenţa acestei complicaţii [2]. Preoperatorindicii importante ne sunt date de...

  12. Apprentissage de la chirurgie orthopédique assisté par ordinateur : Le cas du Système Tutoriel Intelligent TELEOS

    OpenAIRE

    Toussaint, Ben-Manson; Luengo, Vanda; Vadcard, Lucile; Tonetti, Jérôme

    2014-01-01

    El objeto de la investigación presentada en este artículo es el diseño de Entorno Informático de Aprendizaje Humano. El caso estudiado es el Sistema Tutorial Inteligente TELEOS (Technology Enhanced Learning Environment for Orthopaedic Surgery) que apoya al aprendizaje de la cirugía ortopédica percutánea, más precisamente, vertebroplastia y atornillamiento sacroilíaco. El artículo resume el conjunto de los trabajos de investigación que forma la base del desarrollo de este sistema, sus funciona...

  13. La trochantérite tuberculeuse, un diagnostic souvent difficile

    Science.gov (United States)

    Mhammdi, Younes; Boufettal, Moncef; Kharmaz, Mohamed; Lahlou, Abdou; Mahfoud, Mustapha; EL Bardouni, Ahmed; Berrada, Mohamed Saleh

    2016-01-01

    La trochantérite tuberculeuse est une affection rare (<2% des tuberculoses ostéo-articulaires), même en pays à forte endémie, elle est caractérisée par une symptomatologie insidieuse rendant souvent son diagnostic tardif. Les auteurs rapportent une série de 9 cas, le diagnostic a été posé sur des études bactériologiques et histologiques après un bilan d'imagerie (échographie, IRM, TDM). Le traitement de cette affection est médical (antibiothérapie antituberculeuse), et la chirurgie ne trouve sa place qu'en cas de complications et permet d'améliorer l’évolution. PMID:27279938

  14. La trochantérite tuberculeuse, un diagnostic souvent difficile

    Science.gov (United States)

    Mhammdi, Younes; Boufettal, Moncef; Kharmaz, Mohamed; Lahlou, Abdou; Mahfoud, Mustapha; EL Bardouni, Ahmed; Berrada, Mohamed Saleh

    2016-01-01

    La trochantérite tuberculeuse est une affection rare (tuberculoses ostéo-articulaires), même en pays à forte endémie, elle est caractérisée par une symptomatologie insidieuse rendant souvent son diagnostic tardif. Les auteurs rapportent une série de 9 cas, le diagnostic a été posé sur des études bactériologiques et histologiques après un bilan d'imagerie (échographie, IRM, TDM). Le traitement de cette affection est médical (antibiothérapie antituberculeuse), et la chirurgie ne trouve sa place qu'en cas de complications et permet d'améliorer l’évolution. PMID:27279938

  15. Radio-chimiothérapie adjuvante des adénocarcinomes gastriques: à propos de 34 cas et d'une revue de la literature

    OpenAIRE

    James, Laurianne; Dossou, Sepos; Bellfiq, Sarah; Irigo, Joëlle; Ogandaga, Etienne; Mouden, Karima; Loughmari, Saïda; Filali, Dounia; El Majjaoui, Sanaa; Kebdani, Tayeb; Ahid, Samir; Benjafaar, Nourredine

    2014-01-01

    Notre étude consistera en l’évaluation du pronostic des patients porteurs d'un adénocarcinome gastrique opérés et traités par radio-chimiothérapie adjuvante en technique conformationnelle. Entre Janvier 2007 et Décembre 2011, 34 patients ont reçu après une chirurgie radicale (R0 ou R1), un à trois cycles de 5-Fluoro-uracile associé à de l'Elvorine en adjuvant, suivi d'une radio-chimiothérapie selon le même protocole à la dose de 45Gy, puis de deux cycles de chimiothérapie à un mois d'interval...

  16. De l’après-ski à l’après-tourisme, une figure de transition pour les Alpes ?

    Directory of Open Access Journals (Sweden)

    Philippe Bourdeau

    2009-12-01

    Full Text Available Les sports d’hiver occupent une place de premier plan dans le tourisme européen, non seulement du fait de leur poids économique dans les régions de montagne, mais aussi par leur forte dimension symbolique dans la « civilisation des loisirs ». Pourtant l’univers du tourisme hivernal est parcouru par de nombreuses incertitudes liées au changement climatique, mais aussi à des évolutions et des ruptures structurelles qui remettent en question le modèle de développement sur lequel il repose. Ce contexte de mutation permet d’interroger les limites du modèle industriel qui a présidé à l’aménagement des Alpes pour la pratique du ski et d’examiner des figures d’avenir alternatives au « tout ski » et même au « tout tourisme ».Winter sports occupy a prominent place in European tourism, not only because of their economic importance in mountainous areas but also due to their major symbolic significance in the "leisure civilisation". Yet the world of winter tourism is full of uncertainties connected with climate change and also with evolutions and structural breaks that call into question the development model on which it is based. This context of profound change gives us the opportunity to question the limits of the industrial model that has governed the development of the Alps for the practice of skiing and to examine alternative future scenarios to "all-out skiing" and even "all-out tourism".

  17. Long Lake Nat'l. Wildlife Narrative-Jan.-Feb.-Mar.-Apr. 1944

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for Long Lake NWR outlines Refuge accomplishments from January through April of 1944. The report begins by summarizing the weather conditions...

  18. IAEA Newsbriefs. V. 9, no. 2(64). Apr-May 1994

    International Nuclear Information System (INIS)

    This issue gives brief information on the following topics: IAEA Board of Governor's Meetings in Early June, Nuclear Safety Convention, Monitoring and Verification in Iraq, Nuclear Power Regulation in China, Scientific Award for Marine Environment Programme, Assessing Radioactivity Levels at Sea, Safety at Chernobyl, An 'Energy-Ecology Dilemma', Safeguards at Nuclear Fuel Plant, Uranium Resources, Production, and Demand, Radioactive Waste Management, Global Climate Change Studies, Isotopes in Hydrology, Conference on Nuclear Power Option, Nuclear Fusion Research, Nuclear Techniques in Soil/Plant Studies, International Conference on Radiation and Society: Comprehending Radiation Risk, Experimental Fusion Reactor, Middle East NWFZ Concept Discussed, Symbolic Sculpture from South Africa, Update on Nuclear Electricity, and other short information

  19. Structure de la croute terrestre en Algerie d'après les ondes sisiuiques

    Directory of Open Access Journals (Sweden)

    M. BOCKEL

    1972-06-01

    Full Text Available It has been tried to exploit in the best ways all data of
    the algerian shocks till 1969 using the various documents and publications
    found in the Seismological Center of Algiers. Various methods used for the
    near shocks ( < 700 km first and for the farther events later, show that:
    — The velocities are: Pg = 5,55 km/s, Sg = 3,22 km/s, Pn = 7,77 km/s,
    Sn = 4,32 km/s at least for the smaller distances; these velocities, relatively
    little, become greater for distances above 800 km, which means certainly
    a great increase of velocity in the upper mantle.
    — There is no significant variations of velocity between the regions
    of Algiers and Sótif.
    — The algerian shocks are shallow: most of them have a depth less
    than 15 km.

  20. Numerical analysis of APR1400 Steam Generator by CUPID/MARS heat structure coupling

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jae Ryong Lee; Lee, Seung Jun; Pakr, Ik Kyu; Yoon, Han Young [KAERI, Daejeon (Korea, Republic of); Cho, Hyoung Kyu [Seoul National University, Seoul (Korea, Republic of)

    2015-05-15

    To design and analyze steam generators, many computer codes have been developed and used around the world. In this study, the coupled CUPID and MARS code was used for the simulation of boiler side of the PWR steam generator. This paper presents the description of the coupling method, validation for porous media approach against the rod bundle experiment and the preliminary simulation results of PWR steam generator using the coupled code. In the present study, the multi-scale thermal-hydraulic analysis method using the coupled CUPID/MARS code was applied for the simulation of the steam generator. The primary side of the steam generator and other RCS was simulated by MARS and the secondary side was calculated by CUPID with porous media approach. For coupled simulation, the porous medium was applied in order to take into account the effect of the U-tube bundle and other supporting structure which play a role to be a flow resistance. More realistic physical model such as moisture separator slug behavior should be developed for the near future. The application of the coupled simulation should be extended to the accident scenario.

  1. Symposium on Electromagnetic Launcher Technology, 5th, Sandestin, FL, Apr. 3-5, 1990, Proceedings

    Science.gov (United States)

    Gooden, Clarence E.

    1991-01-01

    The present conference on electromagnetic accelerators (EMAs) and railguns (RGs) discusses active-current management for four-rail RGs, the design of a compulsator-drive 60-caliber RG, EMA studies with augmented rails, muzzle-shunt augmentation of conventional RGs, effect of in-bore gas on RG performance, the distributed-energy store RG, plasma diagnostics for high power ignitron development, a review of EMA armature research, RG hybrid armatures, a new solid-armature design concept, and the electrodynamics of RG plasma armatures. Also discussed is RG modeling at speed using three-dimensional finite elements, power supply technology for EMAs, rotating machine power supplies for next-generation EMAs, advanced EMA power supplies with magnetic-flux compression, metal-to-metal switches for large currents, lightweight high-effiency energy-storage transformers, hypervelocity projectile development for EMAs, structural design issues for EMA projectiles, stiff RGs, a reinforced Al conductor for cryogenic applications, mass-stabilized projectile designs for EMA launch, indictively-commutated coilguns, an actively switched pulsed induction accelerator, a plasma gun-augmented electrothermal accelerator, a symmetrical rail accelerator, and a travelling-wave synchronous coil gun.

  2. Underground coal gasification (citations from the Engineering Index Data Base). Report for 1970-Apr 80

    Energy Technology Data Exchange (ETDEWEB)

    Cavagnaro, D.M.

    1980-05-01

    The bibliography presents worldwide research pertaining to underground (in-situ) coal gasification. It includes environmental effects, the different processes and techniques that are used, gas removal, rock fracturing, costs, and economics. (This updated bibliography contains 269 abstracts, 106 of which are new entries to the previous edition.)

  3. Underground coal gasification (citations from the NTIS Data Base). Report for 1979-Apr 80

    Energy Technology Data Exchange (ETDEWEB)

    Cavagnaro, D.M.

    1980-05-01

    The bibliography of Federally-sponsored research cites many aspects of in-situ gasification techniques, including rock fracturing, combustion, gas removal, economics, costs, and environmental factors. (This updated bibliography contains 93 abstracts, 53 of which are new entries to the previous edition.)

  4. Chemical analysis of steel (citations from the NTIS Data Base). Report for 1964-Apr 80

    Energy Technology Data Exchange (ETDEWEB)

    Cavagnaro, D.M.

    1980-05-01

    Information is cited on chemical analysis of boron, nitrogen, hydrogen, sulfur, silicon, carbon, oxygen, aluminum, rare earths, and other trace elements in steel. In addition, research on the determination of major elements, including iron, is covered. New techniques and refinement of older techniques, including x-ray fluorescence, spectroscopy, chromatography, activation analysis, and wet chemical methods are also included. (This updated bibliography contains 240 abstracts, 14 of which are new entries to the previous edition.)

  5. Minimizing infarct size. Annual scientific report, 1 Jul 1975--15 Apr 1976

    Energy Technology Data Exchange (ETDEWEB)

    Braunwald, E.

    1976-04-15

    Several goals were achieved during this period of 9 months, both in the experimental laboratory and in patients with acute myocardial infarction. (1) A study of the effects of aprotinin administration on myocardial ischemic injury, subsequent necrosis and collateral blood flow following acute coronary artery occlusion was carried out to completion. (2) A study of the effect of cobra venom factor on myocardial necrosis was completed and the factors responsible for its action were examined. (3) A comparison was made of the effects of nitroglycerin and nitroprusside on ischemic injury and regional myocardial blood flow in patients with acute myocardial infarction and in dogs with coronary occlusions. (4) A method of direct measurement of infarct size in the rat was developed. It consists of occlusion of the main left coronary artery and the histologic quantification of the infarct at 48 hours and 3 weeks later by serial histologic sections or alternatively by measuring total left ventricular myocardial creative phosphokinase activity. (5) New electrocardiographic methods have been developed in order to evaluate atraumatically the extent of myocardial infarction in patients. (6) Intravenous injection of (113)mIn-ENTMP and (99m)TcENTMP in dogs following coronary artery occlusion permitted a sequential double labeling of the damaged myocardium. (7) Since hyaluronidase is a very effective drug in reducing myocardial damage both in the experimental animal and in patients with acute myocardial infarction, a study was carried out to ascertain its effects on collateral flow.

  6. Sexual dysfunctions after prostate cancer radiation therapy; Dysfonctions sexuelles apres irradiation pour cancer de la prostate

    Energy Technology Data Exchange (ETDEWEB)

    Droupy, S. [Service d' urologie-andrologie, CHU Caremeau, 30 - Nimes (France)

    2010-10-15

    Sexual dysfunctions are a quality of life main concern following prostate cancer treatment. After both radiotherapy and brachytherapy, sexual function declines progressively, the onset of occurrence of erectile dysfunction being 12-18 months after both treatments. The pathophysiological pathways by which radiotherapy and brachytherapy cause erectile dysfunction are multi-factorial, as patient co-morbidities, arterial damage, exposure of neurovascular bundle to high levels of radiation, and radiation dose received by the corpora cavernosa at the crurae of the penis may be important in the aetiology of erectile dysfunction. Diagnosis and treatment of postradiation sexual dysfunctions must integrate pre-therapeutic evaluation and information to provide to the patient and his partner a multidisciplinary sexual medicine management. (authors)

  7. Multiple assets position determination in a 3-dimensional environment using the APRS protocol

    OpenAIRE

    Foutzitzis, Evangelos K.

    2007-01-01

    Increased situational awareness in the battlefield is one of the main objectives in today?s operations and applies to all levels of commands. Several attempts have been made to use tracking devices for detecting and continuously updating the positional data of friendly assets on a map. Current applications like Falcon View fulfill their objective in presenting the location of targets of interest on a digital mapping environment. Falcon View is a geographic information system (GIS) used extens...

  8. Pas de roman avant le mariage, tous les romans après le mariage

    Directory of Open Access Journals (Sweden)

    Tone Smolej

    2002-11-01

    Full Text Available Dans cet article, l’auteur explore la bibliothèque imaginaire des personnages du cycle des Rougon-Macquart, d’Émile Zola. Il se penche plus particulièrement sur les livres lus par deux catégories de personnages : les révoltés à l’égard du système politique et les jeunes filles.

  9. State of the Art Report for Development of Control Element Drive Mechanism of the APR+ Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jae Seon; Choi, Suhn; Song, Chul Hwa

    2008-10-15

    Recently newly-developed nuclear reactors with increased safety and enhanced performance by developed countries in the nuclear area are competing in the global nuclear market. Several reactors, for example AP600 and AP1000 by Westinghouse Electric Co. in USA, EPR by Areva in Europe, APWR by Mitsubishi Heavy Industry in Japan in the pressurized power reactor, are competing to preoccupy the nuclear market during Nuclear Renaissance. Dedicated control element drive mechanism with enhanced performance and increased safety are developed for these new reactors. And load follow capability is required, and it is estimated that load follow requirement make design requirement of a control element drive mechanism harsh. It is necessary to review the current technical state of a control element drive mechanism. This work is aimed to review the design characteristics of a past and current control element drive mechanism for a nuclear reactor and to check the direction and goal of CEDM design development recently.

  10. La formule des traces tordue d'apr\\`es le Friday Morning Seminar

    CERN Document Server

    Labesse, Jean-Pierre

    2012-01-01

    Based on the notes of the Friday Morning Seminar held in the IAS in 1983-1984 (often quoted as Morning Seminar on the Trace Formula), we give a complete and detailed proof of the Twisted Trace Formula in its primitive form i.e. its noninvariant form. ----- Notre ambition est de donner, en nous basant pour l'essentiel sur les notes du Friday Morning Seminar de l'IAS en 1983-1984 (souvent cit\\'e sous le nom de Morning Seminar on the Trace Formula), une version compl\\`ete de la preuve de la formule des traces dans le cas tordu dans sa version primitive c'est-\\`a-dire non invariante.

  11. The Erika tanker shipwreck, one year later. synthesis; Naufrage du petrolier Erika, un an apres. synthese

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-12-01

    In december 1999 the Erika tanker shipwreck broke along the Brittany coast leading to the most important sea pollution by hydrocarbons, since the Amoco-Cadiz. One year after this accident the Ministry of the territory management and of the environment takes stock on the actions carried on after the shipwreck: the management of the POLMAR fund, the shoreline cleaning, the land and water ecosystems restoration, the wastes storage and processing, the ecological consequences. A special part is devoted to the maritime transport regulations and safety and to the victims compensation. (A.L.B.)

  12. Breast cancers and leukaemias after irradiation. Cancers du sein et leucemies apres irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Vathaire, F. de (Centre de Lutte Contre le Cancer Gustave-Roussy, 94 - Villejuif (France))

    1994-01-01

    The influence of new data or recent re-analysis concerning the risks of breast cancer and leukaemia after irradiation is summarized in this article. The risk of breast cancer, particularly after irradiation during childhood, seems to be more important than estimated previously. Because the pattern of risk after irradiation seems to be multiplicative and since breast cancer is very frequent among western populations, these new findings may have important consequences in public health. Despite leukaemias have been known for a long time to be a radioinduced tumour, very little information is available about the effects of age at irradiation and dose rate. (author). 9 refs., 2 tabs.

  13. Optical pattern recognition III; Proceedings of the Meeting, Orlando, FL, Apr. 21, 22, 1992

    Science.gov (United States)

    Casasent, David P. (Editor); Chao, Tien-Hsin (Editor)

    1992-01-01

    Consideration is given to transitioning of optical processing into systems (TOPS), optical correlator hardware, phase-only optical correlation filters, optical distortion-invariant correlation filters, and optical neural networks. Particular attention is given to a test target for optical correlators, a TOPS electronic warfare channelizer program, a portable video-rate optical correlator, a joint transform correlator employing electron trapping materials, a novelty filtered optical correlator using a photorefractive crystal, a comparison of correlation performance of smart ternary phase-amplitude filters with gray-scale and binary input scenes, real-time distortion-tolerant composite filters for automatic target identification, landscaping the correlation surface, fast designing of a circular harmonic filter using simulated annealing, feature-based correlation filters for distortion invariance, automatic target recognition using a feature-based optical neural network, and a holographic inner-product processor for pattern recognition.

  14. Autour d'un petit livre. Alfred Loisy cent ans après

    OpenAIRE

    Losito, Giacomo

    2010-01-01

    Ce volume recueille les actes d'un colloque dont il faut savoir gré à Emile Goichot, Claude Langlois et François Laplanche de l'avoir organisé en mettant à contribution les meilleurs spécialistes allemands, suisses et italiens de la crise moderniste, à côté des historiens français de longue date (Pierre Colin, Bernard Montagnes et le doyen des études de Modernistica, Emile Poulat), des spécialistes des sciences religieuses de l'École Pratique des Hautes Études, des théologiens du Centre Sèvre...

  15. People and things. CERN Courier, Apr 1991, v. 31(3)

    International Nuclear Information System (INIS)

    The article reports on achievements of various people, staff changes and position opportunities within the CERN organization and contains news updates on upcoming or past events: ; In 1992 the XVth International Conference on High Energy Accelerators will be held from 20-24 July at the Congress Centrum, Hamburg, Germany. ; The 100 or so places for the CERN Accelerator School's 'Radiofrequency Engineering for Particle Accelerators' course in Oxford from 3-10 April were sold out well in advance. ; A Symposium on Quantum Physics, in memory of John Stewart Bell who died on 1 October 1990 will be held at CERN on 2-3 May

  16. Thermionics. A bibliography with abstracts. Search period covered: 1970--Apr 1975. [190 references

    Energy Technology Data Exchange (ETDEWEB)

    Grooms, D.W.

    1975-04-01

    Research on thermionic power generation, power plant design, converter design, and basic research on thermionic materials are cited in the bibliography. Spacecraft applications are included. (Contains 190 abstracts).

  17. Construction of APR1000 nuclear power information management system based on international standards

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Seung Hwan [Korea Electric Power Research Institute, Daejeon (Korea, Republic of); Song, Deok Yong; Han, Byung Sub [Enesys Co., Daejeon (Korea, Republic of); An, Kyung Ik; Hwang, Jin Sang [PartDB Co., Daejeon (Korea, Republic of)

    2010-10-15

    In recent years, due to speedy rise of international oil prices, orders of nuclear power plant construction have been in progress by many countries to solve the stable supply of power. Our country has continued to perform nuclear power construction. As only a few developed countries like Japan and European countries have its own nuclear power construction technology, competition among them is keen. Our country has awarded the contract of UAE nuclear power plants based on the accumulated nuclear power plant construction technologies so far. In this regard, KEPCO has recognized the needs of information management system to manage nuclear power information and proceeded the implementation of nuclear power information management system for export-model

  18. Proliferation after the Iraq war; La proliferation apres la guerre d'Irak

    Energy Technology Data Exchange (ETDEWEB)

    Daguzan, J.F

    2004-09-15

    This article uses the Iraq war major event to analyze the approach used by the US to fight against proliferation. It questions the decision and analysis process which has led to the US-British intervention and analyzes the consequences of the war on the proliferation of other countries and on the expected perspectives. Finally, the future of proliferation itself is questioned: do we have to fear more threat or is the virtuous circle of non-proliferation well started? (J.S.)

  19. IAEA Newsbriefs. V. 11, no. 2(71). Apr-May 1996

    International Nuclear Information System (INIS)

    This issue gives brief information on the following topics: Chernobyl Conference sums up Scientific Understanding, International Forum on the Safety of RBMK Reactors, IAEA Board of Governors, Radiological Study of the Mururoa and Fangataufa Atolls, Safeguards Support, Workshop on Modelling Methods for Water Systems, Uranium Market Trends, Security Council Resolution on Iraq, South East Asian NWFZ, Radioactive Waste Management, Nuclear Seminar in Poland, and other short information

  20. Méningite après rachianesthésie

    Science.gov (United States)

    Mouchrif, Issam; Berdaii, Adnane; Labib, Ismail; Harrandou, Moustapha

    2016-01-01

    Les méningites sont des complications rares mais graves des anesthésies péridurales et des rachianesthésies. Les méningites bactériennes sont essentiellement dues à des cocci à Gram positif, ce qui sous-entend une contamination exogène pouvant être le témoin d'une faute d'asepsie. L’évolution est le plus souvent favorable sous traitement, mais au prix d'un accroissement des dépenses de santé et parfois d'importantes séquelles neurologiques. Nous présentons un cas de méningite bactérienne au décours d'une rachianesthésie effectué pour césarienne. PMID:27642477

  1. SOLUTIONS DE LAISSER FAIRE ET AVENIR DE LA PAC APRES 2013

    OpenAIRE

    Fachini, François; Garello, Pierre

    2014-01-01

    International audience Ce Chapitre d'ouvrage soutient que, si la nouvelle Politique Agricole Commune a raison de vouloir laisser les marchés agricoles coordonner l’offre et la demande, elle a tort de délaisser les solutions de laisser faire en matière de production de biens alimentaires sains et d’aménités rurales de qualité.Le développement de cet argument s’organise autour de trois sections : la première évalue les résultats de l’ancienne PAC à l’aune de ses propres objectifs, la seconde...

  2. 14 CFR Appendix H to Part 23 - Installation of An Automatic Power Reserve (APR) System

    Science.gov (United States)

    2010-01-01

    ... the takeoff roll may not be less than— (a) The power necessary to attain, at V1, 90 percent of the... designed to prevent inadvertent deactivation; and (5) Allow normal manual decrease or increase in power up... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Installation of An Automatic Power...

  3. IAEA Newsbriefs. V. 13, no. 2(79). Apr-May 1998

    International Nuclear Information System (INIS)

    This issue gives brief information on the following topics: IAEA Board Meetings Set in May and June, Database of the IAEA's International Nuclear Information Systems (INIS) is being made available over the Internet free of charge, Senior Expert Group Starts Review of IAEA Programmes, IAEA Reports to Security Council on Nuclear Inspections in Iraq, Parties Consider Extending Fusion Research through the ITER Project, Status of Joint Safety and Nuclear Liability Conventions, Proposed Global Convention Against Nuclear Terrorism, Upcoming Symposia and Conferences, New IAEA Books, Nuclear Data File, and other short information

  4. RV Knorr Cruise KN200-4, 13 Apr-03 May 2011. RAPID Mooring Cruise

    OpenAIRE

    Johns, W.; Frajka-Williams, E.; et al, .

    2011-01-01

    This report describes the mooring operations conducted during RV Knorr cruise KN200-4 between 13 April and 3 May 2011. These mooring operations were completed as part of the United Kingdom Natural Environment Research Council (NERC) funded RAPID-WATCH Programme to monitor the Atlantic Meridional Overturning Circulation (MOC) at 26.5°N. The primary purpose on this cruise for the UK team was to service the RAPID Western Boundary moorings while the US teams worked on the Western Boundary Tim...

  5. Quelques aspects des paysages ruraux kosovars d'après guerre

    OpenAIRE

    Barthes, Angela

    2005-01-01

    Les campagnes kosovares sont radicalement transformées depuis la perte du statut de région autonome (1989) et la survenue des conflits. Aujourd'hui, les coopératives agricoles et les industries agro-alimentaires d'état ont cessé de fonctionner. Aujourd'hui, les friches dominent, malgré la reprise micro-économique de structures d'exploitations familiales. En conséquence de la présence de multiples constructions anarchiques inachevées, le paysage ressemble à un vaste chantier désorganisé parsem...

  6. The Development of CPSES Plug-in(CPMP) for APR1400 Computerized Procedure Effective Maintenance

    International Nuclear Information System (INIS)

    The Computerized Procedure System (CPS) is one of the Man Machine Interface (MMI) resources of the Shin-Kori 3 and 4 nuclear power plants. The CPS is a computerized operator support system that enables operating crew to execute procedures in an accurate and fast manner. The Computerized Procedure (CP) is the XML data file in executable format that can be installed in the Procedure eXecution System (PXS) for execution. The CP contains specific information related to a particular procedure (i.e. LOCA). These computerized procedures such as Alarm Response Procedures (ARP) are separated into individual alarm procedure to maximize function interface between CPS and DCS. E.g. 'Procedure open by alarm list'. The procedure writer's burden to manage many procedures has been increased because of separated procedures. This paper introduces Computerized Procedure System Engineering System (CPSES) plug-in that is computerized procedure management program (CPMP) to reduce procedure writer's burden. This paper introduces the main features of CPMP. CPMP reduces procedure writer's or CPX maintainer's burden. This program is implemented and tested by program design requirement

  7. An IntervIew wIth Maria DiCenzo, London AprIl 2011

    OpenAIRE

    Skoog, Kristin

    2011-01-01

    Dr Maria DiCenzo is Associate Professor of English and Film Studies at Wilfrid Laurier University (Canada).1 Her research focuses on feminist media history, particularly late nineteenth- and early twentieth-century women’s print media and social movements, as well as twentieth-century British political theatre. DiCenzo has published widely on the late Victorian and Edwardian feminist periodical press, and she has also provided thoughtful and provocative commentary on the development of femini...

  8. L'avortement en France, vingt ans après la loi

    OpenAIRE

    Fougeyrollas, Béatrice; Zaidman, Claude

    2009-01-01

    Béatrice Fougeyrollas, médecin généraliste qui travaille dans un centre d'IVG depuis plus de 10 ans, nous livre ses réflexions (propos recueillis par Claude Zaidman) Je suis médecin généraliste et je travaille dans un centre d'IVG depuis plus de 10 ans. Dans cette structure, nous pratiquons des interruptions de grossesse mais nous avons aussi une très grosse activité de consultations de contraception et de consultations gynécologiques courantes, c'est-à-dire que les femmes nous demandent de l...

  9. Green fuels, growth engines after petroleum; Les carburants verts, moteurs de la croissance apres le petrole

    Energy Technology Data Exchange (ETDEWEB)

    Mili, Dino

    2010-09-15

    The contribution of the new fuels to a greener environment is important and immediate. Thanks to clean novel technologies and to commercial plant projects in development, companies like Enerkem contribute to satisfy increasing global demand for clean energy. They stimulate local economies by creating jobs in an industry that offers real growth potential. Green fuels will gradually allow us to let go of non sustainable energy sources like oil to adopt a way of life based on sustainable development. They will also allow a shift towards a green economy. [French] La contribution des nouveaux carburants a un environnement plus vert est importante et immediate. Grace a des technologies propres novatrices et a des projets d'sines commerciales en developpement, des entreprises comme Enerkem contribuent a satisfaire a la demande mondiale croissante en energie propre. Elles stimulent les economies locales par la creation d'emplois dans une industrie qui offre un veritable potentiel de croissance. Les carburants verts permettront graduellement de nous affranchir des sources d'energie non renouvelables comme le petrole pour adopter un mode de vie base sur le developpement durable. Ils permettront aussi un virage vers une economie verte.

  10. Musique et conflits armés après 1945

    OpenAIRE

    Anagnostou, Panagiota; Buch, Esteban; Castanet, Pierre Albert; Cusick, Suzanne G.; Fryberger, Annelies; Gómez Gálvez, Mauricio; Grant, Morag Josephine; Gribenski, Fanny; Hallam, Huw; Jardin, Étienne; Mayaud, Isabelle; Nuxoll, Cornelia; Pédelaborde, Cindy; Ramaut-Chevassus, Béatrice; Rogers, Jillian

    2014-01-01

    Dans son ouvrage De la guerre, paru pour la première fois en 1832, Carl von Clausewitz affirme que la guerre se situe à l’intérieur des rapports politiques : elle serait un véritable « instrument politique, une continuation des rapports politiques, la réalisation des rapports politiques par d’autres moyens ». Ainsi, l’un des apports les plus importants de la pensée de Clausewitz à la compréhension de la guerre, résultant de ce postulat, serait que celle-ci ne constitue pas la rupture d’un pro...

  11. Securite nutritionnelle a Haiti : situation avant et apres le seisme et recommandations pour l'avenir

    OpenAIRE

    Bassett, Lucy

    2010-01-01

    Children in Haiti are born into some of the harshest conditions on the planet, and are left at a disadvantage in terms of growth, development, and potential to thrive. Malnutrition rates in Haiti are among the worst in the Latin America and Caribbean Region. Nearly one-third of all children under-five suffer from stunted growth and three quarters of children 6-24 months are anemic. Malnutr...

  12. Post-mining in Walloon region; L'apres-mine en region wallonne

    Energy Technology Data Exchange (ETDEWEB)

    Arnould, R. [Liege Univ. (Belgium); Delbeuck, C.; Flamion, B. [Direction Generale des Ressources naturelles et de l' Environnement, Jambes (Belgium)

    2003-07-01

    several studies are presently undertaken in the Walloon Region so as to assess the long term environmental impact caused by the shutting down of coal mines and their pumping operations. In many locations, new problems are encountered, such as sudden underground water appearance at hill slopes, coal heaps instability or flooding of underground cellars. Slope instability increase risks. The main goals of the presented studies are to suppress or at least to limit those risks and inconveniences and propose solutions to be implemented in the framework of the existing dewatering facilities built by the Walloon Region and local authorities in mines induced subsidence areas. (authors)

  13. IAEA Newsbriefs. V. 14, no. 2(83). Apr-May 1999

    International Nuclear Information System (INIS)

    This issue gives brief information on the following topics: Nuclear Safety: States Taking 'Steps in Right Direction', Contracting Parties to Convention on Nuclear Safety, Nuclear Power Worldwide, Nuclear's Future: Director General Address in Japan, Year 2000 Programme and Budget Goes Before IAEA Board, The IAEA and Y2K Issues: Reports, Workshops, Internet Links, Strengthened Safeguards System: Status of Additional Protocols, States Join International Conventions in Nuclear Fields, IAEA International Scientific Symposia and Seminars in 1999, In Memoriam: Munir Ahmad Khan, and other short information

  14. Radioactivity survey of total diet for Saitama residents. Apr. 2011 - Mar. 2013

    International Nuclear Information System (INIS)

    In order to estimate the human intake and the committed effective dose of several radioactive materials, the duplicate diet samples sampled from Saitama residents were analyzed. The average daily intakes of 134Cs and 137Cs in 2011 were 0.43 and 0.48 Bq/person·day, and those in 2012 were 0.065 and 0.15 Bq/person·day. The committed effective doses in 2011 and 2012 are estimated to be 5.5 and 1.1 μSv, respectively. The estimated dose in 2011 is almost 80 times higher than that before the occurrence of Fukushima Daiichi Nuclear Power Plant accident. However, it is found that this dose is less than 1% of the annual effective dose limit for members of the public (1 mSv/year). (author)

  15. Acute exercise does not induce an acute phase response (APR) in Standardbred trotters

    DEFF Research Database (Denmark)

    Kristensen, Lena; Buhl, Rikke; Nostell, Katarina;

    2014-01-01

    ), and iron], muscle enzymes [creatinine kinase (CK) and aspartate transaminase (AST)], and hemoglobin were assessed in 58 Standardbred trotters before and after racing. Hemoglobin levels increased and iron levels decreased 12 to 14 h after racing and haptoglobin concentrations, white blood cell counts......, and iron levels were decreased 2 and/or 7 d after racing. Concentrations of CK, AST, SAA, and fibrinogen were unaltered in response to racing. Acute strenuous exercise did not elicit an acute phase reaction. The observed acute increase in hemoglobin levels and decreases in haptoglobin and iron levels may...

  16. LHC Beam Splash seen by the ATLAS detector, 7 Apr 2015 - Run 260466 - event 22425

    CERN Multimedia

    Adam Bourdarios, Claire

    2015-01-01

    Event display of one of the collimator "splash" event seen by the ATLAS experiment in LHC Run-2 , on Tuesday April the 7th : event 22425, run 260466. The collimator position is 140m in front of the ATLAS interaction point. The spray of particles enters ATLAS from the left hand side of the picture. The length of the yellow bars indicates the energy deposited in the ATLAS calorimeter.

  17. Salvage treatments for prostatic radiation failure; Traitements de rattrapage apres radiotherapie prostatique

    Energy Technology Data Exchange (ETDEWEB)

    Baumert, H. [Service d' urologie, groupe hospitalier Paris Saint-Joseph, 75 - Paris (France)

    2010-10-15

    Local recurrence after external radiotherapy or brachytherapy occurs in 30% of patients treated for prostate cancer. These recurrences can be localised to the prostate and controlled by salvage treatment. Salvage prostatectomy is the gold standard treatment, however, it is associated with a high morbidity rate. Minimally invasive treatments such as cryo-therapy and high intensity focused ultrasound (HIFU) can be proposed to treat local recurrences. Indications, complications and oncological results of these salvage treatments are discussed in this article. (author)

  18. Coal conversion control technology. Volume III. Economic analysis; appendix. Final report Apr 77-Nov 78

    Energy Technology Data Exchange (ETDEWEB)

    Bostwick, L.E.; Smith, M.R.; Moore, D.O.; Webber, D.K.

    1979-10-01

    This volume is the product of an information-gathering effort relating to coal conversion process streams. Available and developing control technology has been evaluated in view of the requirements of present and proposed federal, state, regional, and international environmental standards.

  19. Solar - there is a life after Photowatt; Solaire - Il y a une vie apres Photowatt

    Energy Technology Data Exchange (ETDEWEB)

    Charbonnier, V.

    2012-01-26

    This article evokes the activities of some innovative French companies involved in the solar sector: software development for the assessment of solar installations, silicon ingot fabrication (for the fabrication of wafers used in photovoltaic cells), electro-erosion machining. These companies are located in the Rhone-Alpes region and try to take advantage of their technological innovation potential. An article recalls the rise and fall of Photowatt, a company which used to be a world leader of the photovoltaic sector in the 1990's

  20. LHC Beam Splash seen by the ATLAS detector - 5 Apr 2015 - run 260272 - event 6539

    CERN Multimedia

    ATLAS Collaboration

    2015-01-01

    Event display of one of the collimator "splash" events seen by the ATLAS experiment in LHC Run-2, on Tuesday April the 5th : run 260272, event 6539 . The collimator position is 140m in front of the ATLAS interaction point.

  1. Aspekty managementu hudebního festivalu Apríles

    OpenAIRE

    Wildová, Veronika

    2012-01-01

    The work deals with the management of cultural events in the open air, and focuses on music festivals. It examines the development of the concept of popular music festivals since their beginning and maps festivals in the Czech Republic. It is based on the personal experience of the author with the organization of the festival, and describes various aspects of event management from concept to its realization. Points out the difficulties that occur in the organization, and proposes a solution o...

  2. Study on the VFD (Variable Frequency Drive) for RCP (Reactor Coolant Pump) Motors of APR1400

    International Nuclear Information System (INIS)

    Most industrial facilities are continually searching for ways to reduce energy costs while increasing or maintaining current production. In terms of electric motors, Variable Frequency Drive (VFD) units represent a critical opportunity for energy savings. Currently, VFDs are used on about ten (10) percent of industrial process motors, and this percentage is increasing every year. Properly applied VFDs have been documented to save as much as fifty percent of the energy consumed by certain industrial processes. Nuclear Power - Power plants in general and Nuclear Power Plants (NPPs) in particular are slow to adopt new technology. The nuclear power industry requires a nearly absolute demonstration through operating experience in other industries in which the new approach will result in a net improvement in plant reliability without any surprises. Only recently has the nuclear industry begun to adapt VFD units for large motors. Specifically, there are several examples in the Boiling Water Reactor (BWR) fleet of replacing Motor-Generator (M-G) sets with VFD units for Reactor Recirculation (RR) pump motor service. At one station, VFD units were introduced upstream of the Circulating Water (CWP) pump motors to address environmental issues. They units are taking advantage of VFD technology whose benefits include increased reliability, reduction in electrical house load, improved flow control, and reduced maintenance. RCP Application - In the case of new generation, it has been reported that the Westinghouse AP1000 will make use of VFD units for the Reactor Coolant Pump (RCP) motors

  3. Infrared optical materials VI; Proceedings of the Meeting, Orlando, FL, Apr. 4, 5, 1988

    Science.gov (United States)

    Musikant, Solomon

    1988-01-01

    Recent advances in IR optics are discussed in reviews and reports. Topics addressed include IR sensors and mirrors, IR-transmitting ceramics, IR waveguides, and IR glasses. Consideration is given to in situ visualization of the solid-liquid interface during crystal growth, (HgZn)Te IR photovoltaic detectors, lanthana-strengthened yttria IR-transmitting materials, high-temperature transmission measurements of IR window materials, fabrication of heavy-metal-fluoride glass fibers containing ultralow amounts of oxygen and water, and the material properties required for hollow fibers transmitting high-power IR radiation.

  4. Capital and operating costs for industrial boilers. Final report Apr-Jun 79

    Energy Technology Data Exchange (ETDEWEB)

    Gibbs, L.L.; AbrahaM, J.P.; Noe, N.D.; Forste, D.S.; Kimball, H.T.

    1979-06-01

    The report provides estimates of capital and operating costs for industrial boilers. Costs are related to the type of fuel fired, firing design and rated capacity. Both package and field-erected boilers are evaluated. Fuels considered include coal, residual oil, distillate oil and natural gas. Firing designs for coal include underfeed-stoker, spreader-stoker and pulverized. Rated capacities range from 15(10 to the 6th)Btu/hr for oil and gas to 700(10 to the 6th)Btu/hr for coal. Costs are developed on a study estimate basis. Individual boiler cost estimates were plotted and cost equations developed for total equipment, installation (direct and indirect) and operating costs (variable and fixed).

  5. APR-5000-XLS阵列封装返工系统

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    APR—5000-XLS阵列封装返工系统可处理BGA,CSP,LGA,Micro SMD,MLF(Micro—Lead Frame),BCC(Bumped Chip Copponent)多种封装。其可处理的板尺寸达610cm-610cm,厚度达6.35mm。双程、全空气底部预热,能处理大小不同规格的PCB板。采用5个热电偶输入和闭环RTD温度控制,可分析多点温度,精细控制返工区的温度。计算机监控时间、温度、加热气流量,保证进程控制和高重复性。

  6. Après nous, le déluge / Toomas Hendrik Ilves

    Index Scriptorium Estoniae

    Ilves, Toomas Hendrik, 1953-

    2006-01-01

    Euroopa Liidu põhiseadusliku leppe läbikukkumisest, vanade liikmesriikide suhtumisest uutesse, Venemaa lootusest Euroopa Liidu nõrgenemisele. Eesti peaks tihendama koostööd teiste uute liikmesriikidega oma ühishuvide kaitsel. Ilmunud ka: Sirp : Diplomaatia 8. juuli 2005 nr. 22/23, lk. 2-4

  7. LHC Beam Splash seen by the ATLAS detector - 7 Apr 2015 - Run 260466 - event 14046

    CERN Multimedia

    Adam Bourdarios, Claire

    2015-01-01

    Event display of one of the collimator "splash" event seen by the ATLAS experiment in LHC Run-2 , on Tuesday April the 7th 2015 : event 14046, run 260466. The collimator position is 140m in front of the ATLAS interaction point.

  8. Monthly results of measurements. Apr 1999; Tableaux mensuels des mesures. Avril 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  9. Monthly results of measurements: Apr 1997; Tableaux mensuels des mesures. Avril 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  10. Monthly results of measurements: Apr 2001; Tableaux mensuels des mesures. Avril 2001

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  11. The energy stakes - After Fukushima. 2. ed.; Les enjeux de l'energie - Apres Fukushima

    Energy Technology Data Exchange (ETDEWEB)

    Iacona, Estelle; Taine, Jean; Tamain, Bernard

    2012-01-11

    The energy question today is worldwide and depends on major geopolitical stakes (demography, development, water, health, environment, research, risks). The energy must be universally produced and distributed together with minimizing pollutions, nuclear risks and CO{sub 2} emissions. This new edition of 'the energy stakes' is fully updated and approaches some of the main questions that any responsible citizen should ask. It comprises 3 parts dealing with: a comprehensive review of the energy question in most of countries in the world, the constraints and challenges to take up to manage energy in an optimum way, and a prospective study about the control of energy consumption and about the existing technical solutions. (J.S)

  12. Zorn: Avant/Après/Passé [przekład

    Directory of Open Access Journals (Sweden)

    John Lowell Brackett

    2012-06-01

    Full Text Available Krótki wywiad Witolda Wachowskiego z Johnem Zornem zawiera wiele cennych spostrzeżeń związanych z estetyką tego kompozytora. Rzekoma niechęć Zorna do publiczności, jego wiara w kreatywny instynkt „artysty” oraz jego przekonanie o transcendentalnej naturze dzieł muzycznych (które są bramą do świata „prawdy” i „piękna” niczym refren powtarzają się w wielu wywiadach z muzykiem. Zorn w krótkim wywiadzie z Wachowskim podkreśla właśnie te przekonania, dlatego możemy przyjąć, że stanowią one fundament jego muzycznej i artystycznej estetyki. Dla każdego, kto posiadł choćby podstawową wiedzę o zachodniej tradycji estetycznej, jest jasne, że te same cechy i stanowiska estetyczne charakteryzują muzyczne instytucje wspólne dla zachodniej tradycji artystycznej, a w szczególności „romantyczny” ideał muzyki i kompozytora rozwinięty w XIX wieku. Filozofowie (głównie Hegel i Kant razem z krytykami muzycznymi i kompozytorami (Schiller, Hoffmann, Schlegel, Schuman, Hanslick przyczynili się do stworzenia romantycznej estetyki muzycznej w XIX wieku, akcentującej rolę artysty („geniusza” lub „boga”, który tworzy „dzieła” odsłaniające – poprzez czysto muzyczne związki istniejące niezależnie od wrażliwości słuchacza – ukryte światy prawdy i piękna, światy odległe od trosk życia codziennego. Zważywszy na bliskie związki Zorna z estetykami/filozofami XIX-wiecznymi, można powiedzieć, że wyznaje on „romantyczny” pogląd na muzykę i sztukę.

  13. Study on the VFD (Variable Frequency Drive) for RCP (Reactor Coolant Pump) Motors of APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jung Ha; Robert, M. Field; Kim, Tae Ryong [Department of NPP Engineering, KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

    2014-10-15

    Most industrial facilities are continually searching for ways to reduce energy costs while increasing or maintaining current production. In terms of electric motors, Variable Frequency Drive (VFD) units represent a critical opportunity for energy savings. Currently, VFDs are used on about ten (10) percent of industrial process motors, and this percentage is increasing every year. Properly applied VFDs have been documented to save as much as fifty percent of the energy consumed by certain industrial processes. Nuclear Power - Power plants in general and Nuclear Power Plants (NPPs) in particular are slow to adopt new technology. The nuclear power industry requires a nearly absolute demonstration through operating experience in other industries in which the new approach will result in a net improvement in plant reliability without any surprises. Only recently has the nuclear industry begun to adapt VFD units for large motors. Specifically, there are several examples in the Boiling Water Reactor (BWR) fleet of replacing Motor-Generator (M-G) sets with VFD units for Reactor Recirculation (RR) pump motor service. At one station, VFD units were introduced upstream of the Circulating Water (CWP) pump motors to address environmental issues. They units are taking advantage of VFD technology whose benefits include increased reliability, reduction in electrical house load, improved flow control, and reduced maintenance. RCP Application - In the case of new generation, it has been reported that the Westinghouse AP1000 will make use of VFD units for the Reactor Coolant Pump (RCP) motors.

  14. Oncoplastie avec conservation mammaire dans le traitement du cancer du sein: à propos de 16 cas

    Science.gov (United States)

    Bouzoubaa, Wail; Laadioui, Meryam; Jayi, Sofia; Alaoui, Fatime Zahra Fdili; Bouguern, Hakima; Chaara, Hikmat; Melhouf, Moulay Abdelilah

    2015-01-01

    Le cancer du sein est actuellement le cancer le plus fréquent chez la femme, et pose un véritable problème diagnostique et thérapeutique. Le dépistage des lésions à un stade de plus en plus précoce, a permis une extension des indications du traitement conservateur radiochirurgical, qui était initialement limitées aux tumeurs de moins de 3 cm, unifocales, non inflammatoires. Par ailleurs, l'utilisation de traitements préopératoires permet d’étendre les indications du traitement conservateur à des tumeurs plus volumineuses. Parallèlement à cette extension des indications de conservation mammaire, on a observé le développement de nouvelles approches thérapeutiques notamment la chirurgie oncoplastique, technique du ganglion sentinelle et chirurgie stéréotaxique, dont les résultats initiaux sont très encouragent. A travers cette étude réalisée dans le service de gynécologie et obstétrique II du CHU HASSAN II de FES au MAROC, après l'analyse rétrospective de 16 patientes traitées par traitement conservateur et oncoplastie, nous avons voulus montrer notre aptitude a réalisé ses techniques chirurgicales et a bien prendre en charge ces patientes, mais aussi évaluer ces techniques en termes de résultat carcinologique et de résultat esthétique, aussi en terme de survie globale, survie sans métastase et en termes de récidive locale entre les plasties mammaires et les traitements usuels: mastectomie et traitement conservateur classique. PMID:26430477

  15. La radiothérapie du cancer de l'endomètre: expérience de l'institut national d'oncologie à propos de 52 cas

    Science.gov (United States)

    Mezouri, Imane; Berhili, Soufiane; Mouhajir, Nawal; Bellefqih, Sara; Elkacemi, Hanan; Kebdani, Tayeb; Benjaafar, Noureddine

    2016-01-01

    Le cancer de l'endomètre est le cancer gynécologique le plus fréquent en occident. Il concerne principalement les femmes ménopausées. L'objectif de notre travail est de rapporter l'expérience du service de radiothérapie à l'Institut National d'Oncologie (INO) dans la prise en charge du cancer de l'endomètre. Nous avons analysé rétrospectivement 52 cas de cancer de l'endomètre traités dans le service de radiothérapie de l'INO entre 2007 à 2009. Les données collectées à partir des dossiers médicaux de nos patientes concernaient les aspects épidémiologiques, cliniques, thérapeutiques et évolutifs de ce cancer. La médiane d’âge des patientes était de 57 ans, 87% étaient ménopausées. Le délai moyen de consultation était de six mois. Le maitre symptôme était des métrorragies chez 51 patientes. Le diagnostic histologique a été porté sur un curetage biopsique de l'endomètre dans 51% des cas. L'examen anatomopathologique a montré un adénocarcinome endométrioïde dans 92% des cas. Après le bilan, 27% des patientes étaient stade I, 30% stade II, 20% stade III et 1% stade IVA selon la classification de la Fédération Internationale de Gynécologie Obstétrique (FIGO). Après la chirurgie, 51% des patientes ont reçu une radiothérapie externe. La dose délivrée était de 46 Gray (Gy). Une curiethérapie du fond vaginal a été délivrée chez toutes les patientes. Sur le plan évolutif, 83% des patientes étaient toujours suivies en situation de bon contrôle de leur maladie, 8% ont eu une récidive locorégionale et 4% avaient des métastases à distance. Ainsi, le cancer de l'endomètre est un cancer dont le traitement repose sur la chirurgie. La radiothérapie est le traitement adjuvant principal. PMID:27279969

  16. The place radiotherapy alone with respect to surgery and radiotherapy in locally advanced vulva cancers; Place de la radiotherapie seule par rapport a la chirurgie et la radiotherapie dans les cancers vulvaires localement evolues

    Energy Technology Data Exchange (ETDEWEB)

    Mansouri, S.; Naim, A.; Moukhlissi, M.; Tawfik, N.; Bouchbika, Z.; Benchekroun, N.; Jouhadi, H.; Sahraoui, S.; Benider, A. [Centre de radiotherapie-oncologie, centre hospitalier universitaire, Ibn-Rochd, Casablanca (Morocco)

    2011-10-15

    The author report a study which aimed at evaluating the place or radiotherapy associated with surgery and of radiotherapy without surgery when taking into care locally advanced vulva cancers. The study is based on 46 cases. After 24 months, different aspects, such as recurrence and survival, have been assessed. It appears that there is no survival difference without recurrences between both sets. Short communication

  17. Chemotherapy, brachytherapy and surgery of locally evolved uterine cervix carcinomas: prognosis factors of local control and global survival; Chimioradiotherapie, curietherapie et chirurgie des cancers du col uterin localement evolues: facteurs pronostiques de controle local et de survie globale

    Energy Technology Data Exchange (ETDEWEB)

    Laude, C.; Montella, A.; Montbarbon, X.; Malet, C.; Racadot, S.; Pommier, P. [Centre Leon-Berard, 69 - Lyon (France); Mathevet, P. [Hopital Femme-Mere-Enfant, Hospices Civils de Lyon, 69 - Lyon (France); Buenerd, A. [Centre de Pathologie Est, Hospices Civils de Lyon, 69 - Lyon (France)

    2009-10-15

    The protocol used allows an excellent local control of the uterine cervix carcinoma with an acceptable morbidity. To anticipate the presence of a tumor residue can be an evolution in the therapy management after external radiotherapy, particularly in optimized image-guided brachytherapy (MRI and PET)New utero vaginal applicators with parameters implantation allow to realise the dose complement at the distal parameters. These advances make consider an improvement of results in the management of locally evolved uterine cervix carcinomas. (N.C.)

  18. SPECT-CT and parathyroid scintigraphy: about an imaging case in surgery; TEMP-TDM et scintigraphie parathyroidienne: a propos d'un cas de l'imagerie a la chirurgie

    Energy Technology Data Exchange (ETDEWEB)

    Venel, Y.; Rouvre, M.; Baulieu, J.L. [CHRU Bretonneau, Service de medecine nucleaire et ultrasons, 37 - Tours (France); Lardy, H. [CHRU Clocheville, service de chirurgie viscerale et plastique, 37 - Tours (France); Nivet, H. [CHRU Bretonneau, Service de nephrologie, 37 - Tours (France); Sirinelli, D. [CHRU Clocheville, service de radiologie pediatrique, 37 - Tours (France)

    2010-07-01

    Purpose: With the introduction of hybrid cameras raises the question of adaptation protocols, including parathyroid scintigraphy where several types of acquisitions are possible. The case we are going to exhibit helped to adapt our protocol by anatomical verifying during surgery with isotopic detection. Conclusions: With this case, we decided to make in routine the protocol including a MIBI injection, a cervico-thoracic image at 10 minutes and at 1 hour and 15 minutes then a coupled SPECT at 1 hour and 30 minutes. The dual isotope scintigraphy is reserved for the failures of the previous method. (N.C.)

  19. Vliv médií na vnímání vlastního těla s důrazem na problematiku estetické chirurgie

    OpenAIRE

    Vančurová, Olga

    2010-01-01

    The bachelor thesis is related to the cosmetic surgery as a trend of the modern times. The thesis consists of theoretical and practical part. The theoretical part is divided into five chapters. The first, second and third chapter deal with the explanation of the terms plastic and cosmetic surgery, history of plastic and cosmetic surgery and the chosen procedures. The fourth chapter discusses the researches carried out in the field of cosmetic surgery, the medialized of cosmetic surgery and th...

  20. Surgery of congestive heart failure - the role of computed tomography in the pre- and postsurgical diagnostic evaluation; Chirurgie der Herzinsuffizienz - Stellenwert der Computertomographie in der prae- und postoperativen Diagnostik

    Energy Technology Data Exchange (ETDEWEB)

    Lembcke, A.; Kivelitz, D.E.; Rogalla, P.; Dewey, M.; Klessen, C.; Hamm, B.; Enzweiler, C.N.H. [Inst. fuer Radiologie, Charite - Universitaetsmedizin Berlin, Charite Campus Mitte, Berlin (Germany); Dohmen, P.M.; Konertz, W.F. [Klinik fuer Kardiovaskulaere Chirurgie, Charite - Universitaetsmedizin Berlin, Charite Campus Mitte, Berlin (Germany); Wiese, T.H. [Inst. fuer Radiologie, Augusta-Kranken-Anstalt, Bochum (Germany)

    2005-07-01

    The treatment of advanced, drug resistant congestive heart failure gains in importance in the field of cardiac surgery. Cardiac imaging for preoperative assessment and follow-up focuses on the determination of ventricular volumes and function as well as on the detection of postoperative complications. Computed tomography (CT) is highly accurate irrespective of the individual patient's anatomic situation, has a low examiner dependence and short examination time, does not require an arterial vascular access and can be performed in patients with metal implants. CT is the modality of choice in the follow-up of heart transplants to detect extracardiac and cardiac complications including coronary calcifications as an early sign of transplant vasculopathy. In addition, CT visualizes the elements of mechanical assist devices and can identify their possible local cardiac and mediastinal complications CT can detect fibrolipomatous involution of the mobilized muscle flap in dynamic cardiomyoplasty and can depict fibrous reactions along the epicardial mesh implant in passive cardiac containment. Further indications include assessment of typical local postoperative complications, such as intrathoracic infection and mediastinal bleeding, intracardiac thrombus formation or pericardial effusion. CT is routinely used for evaluating bypass patency but is limited in assessing associated valve defects since it does not visualize flow. (orig.)

  1. Concerts & Opera

    Index Scriptorium Estoniae

    2006-01-01

    Kammerorkestri Kremerata Baltica kontserdid: 19. apr. Londonis LSO St Lukesis, 21. apr. Oxfordis Sheldonian Theatre'is, 17. apr. Aldeburghis, 20. apr. Manchesteris Bridgewater Hallis, 23. apr. Wales Millennium Centre'is, 22. apr. Edinburghis Usher Hallis

  2. Measuring ocean waves from space; Proceedings of the Symposium, Johns Hopkins University, Laurel, MD, Apr. 15-17, 1986

    Science.gov (United States)

    Beal, Robert C. (Editor)

    1987-01-01

    Papers are presented on ocean-wave prediction; the quasi-universal form of the spectra of wind-generated gravity waves at different stages of their development; the limitations of the spectral measurements and observations of the group structure of surface waves; the effect of swell on the growth of wind wave; operational wave forecasting; ocean-wave models, and seakeeping using directional wave spectra. Consideration is given to microwave measurements of the ocean-wave directional spectra; SIR research; estimating wave energy spectra from SAR imagery, with the radar ocean-wave spectrometer, and SIR-B; the wave-measurement capabilities of the surface contour radar and the airborne oceanographic lidar; and SIR-B ocean-wave enhancement with fast-Fourier transform techniques. Topics discussed include wave-current interaction; the design and applicability of Spectrasat; the need for a global wave monitoring system; the age and source of ocean swell observed in Hurricane Josephine; and the use of satellite technology for insulin treatment.

  3. The supplication: Tchernobyl, chronicles of the world after the apocalypse; La supplication: Tchernobyl, chroniques du monde apres l`apocalypse

    Energy Technology Data Exchange (ETDEWEB)

    Alexievitch, S

    1998-12-31

    This book is the result of a three year inquiry in the region of Tchernobyl (Russia) after the reactor accident, during which the author has questioned the population and collected their statement in order to reconstruct their mental feeling after the catastrophe. (J.S.)

  4. Un nouveau Risorgimento du cinéma : Rossellini lecteur de Stendhal (cent cinquante ans après

    Directory of Open Access Journals (Sweden)

    Carlo Testa

    2012-07-01

    Full Text Available Cet article fait d'abord le tour des raisons qui rendaient le Risorgimento (parachevé par l'unification de 1861 un thème actuel pour le public italien de 1961, au moment du dit « miracolo economico ». C'est en profitant de cette actualité, au moment du premier centenaire de la nation italienne, que sortit le film Vanina Vanini, re-créé par Roberto Rossellini sur la base de la nouvelle homonyme de Stendhal. Pourtant, malgré le moment favorable, la re-création littérature-cinéma opérée par Rossellini ne s'avéra pas fructueuse, à cause de certains obstacles matériels et commerciaux qui firent entrave aux intentions artistiques du metteur en scène. L'article examine ces contraintes -- qui hantaient et hantent toujours l'industrie cinématographique de par sa structure même -- et souligne que Rossellini sut lui-même tirer des conclusions courageusement radicales à partir de l'échec artistique essuyé dans son entreprise stendhalienne. Le film Vanina Vanini constitua le tournant décisif dans l'évolution du film de fiction de Rossellini vers les films didactiques et pédagogiques qu'il tourna en Italie et en France pendant les 15 dernières années de sa carrière.

  5. Eastern Gulf of Mexico April 1997 Ocean Currents, Geographic NAD83, MMS (1999) [ocean_currents_egom_Apr_MMS_1997

    Data.gov (United States)

    Louisiana Geographic Information Center — This is one data set of a data package consisting of thirteen point data sets that have as attributes the direction and velocity of ocean currents in the 'eastern'...

  6. Western Gulf of Mexico April 1994 Ocean Currents, Geographic NAD83, MMS (1999) [ocean_currents_wgom_Apr_MMS_1994

    Data.gov (United States)

    Louisiana Geographic Information Center — This is one data set of a data package consisting of thirteen point data sets that have as attributes the direction and velocity of ocean currents in the western...

  7. RTE: a first assessment after one year of existence; RTE: un premier bilan apres une annee d'existence

    Energy Technology Data Exchange (ETDEWEB)

    Merlin, A. [Reseau de Transport et d' Electricite, RTE, 92 - Paris la Defense (France)

    2001-11-01

    Just over a year ago, on 1 July 2000, the manager of the French public Electricity Transport Network - RTE - entered the French electricity scene. Its creation is a result of the law of 10 February 2000 concerning the modernization and development of the electric utility, which transposes into French Law the European directive of December 1996. This law, which organizes the introduction in the market French electricity scene, foresees that the transport network manager is independent from EDF's other activities, for this network can now be used not solely by the famous operator. The entire equipment and most of the skills which contribute to the management of the public transport network were thus separated from EDF's other activities and merged into what has become RTE. This separation has been carefully prepared as soon as the principles of introduction of competition in the electricity market were established by the European directive. It was created in six month with the help of the regulatory and control authorities, the Secretary of State for Industry and the Electricity Regulation Committee (CRE). This anticipation has enabled a smooth transition and if RTE remains with EDF,it is today completely independent for managerial, accounting and financial aspects. (author)

  8. Quality of life after radiotherapy for prostate cancer; Qualite de vie apres radiotherapie pour un cancer localise de la prostate

    Energy Technology Data Exchange (ETDEWEB)

    Joly, F. [Service d' oncologie medicale, CLCC Francois-Baclesse, 14 - Caen (France); CHU Cote-de-Nacre, 14 - Caen (France); Degrendel, A.C. [Service de radiotherapie, CLCC Francois-Baclesse, 14 - Caen (France); Guizard, A.V. [Registre general des tumeurs du Calvados, CLCC Francois-Baclesse, 14 - Caen (France)

    2010-10-15

    The goal of localized prostate cancer radiotherapy is to cure patients. The decision-making must integrate the survival but also the quality of life of patients. Some French validated self-reported questionnaires are available to evaluate quality of life. Whatever the treatments (radical prostatectomy, brachytherapy, external beam radiation, with or without hormono-therapy), even if patients report more sequelae, their long-term quality of life is similar to that of the general population, except for patients treated with hormono-therapy who complain more decline of physical quality of life. In comparison with prostatectomy, patients treated with external beam radiation report less long-lasting urinary symptoms, but more bowel side effects, with no difference in global quality of life. Sexual disorders are initially less important with external beam radiation but increase over time. Brachytherapy shows no sexual function preservation benefit relative to radiation and may be less favourable with more urinary sequelae. The association of hormono-therapy and external beam radiation decreases the quality of life of the patients, with a negative impact on vitality, sexuality and increase urinary disorders. Intensity-modulated radiotherapy (IMRT) seems to better preserve the long-term digestive quality of life in comparison with conformal radiation therapy. Post-prostatectomy could induce more digestive toxicity, such as rectal irritation. The adjunction of hormono-therapy to radiation, the previous medical history of abdominal surgery, the field of radiation and the acute reactions to radiation are the main predictive factors to late toxicity and should be considered in the choice of initial treatment and for the follow-up. (authors)

  9. Symposium on Electromagnetic Launch Technology, 6th, Univ. of Texas, Austin, Apr. 28-30, 1992, Proceedings

    Science.gov (United States)

    Grosser, Julie K.

    1993-01-01

    The present conference discusses topics in the military and commercial applications of electrical launcher systems, electromagnetic and electrothermal 'railgun' launchers, 'coilguns', armature and launcher designs, power-conditioning and energy storage systems, and launcher materials and structures and their diagnostics. Attention is given to an earth-to-orbit railgun launcher, polyphase and multiphase railguns, hypervelocity projectile design, determining the Lorentz forces in plasma armatures, pulse power generators, advanced compulsator technology, airborne-platform electric launcher applications, magnetic design for structural stiffness, current multipliers, pulse-forming network design, and cannon-caliber electromagnetic launchers.

  10. Atmospheric particle detectors. 1964-April 1980 (citations from the NTIS Data Base). Report for 1964-Apr 80

    Energy Technology Data Exchange (ETDEWEB)

    Cavagnaro, D.M.

    1980-05-01

    The cited reports cover detectors that are used primarily in air pollution and mine emission applications. Citations include monitoring site selection, applicable instrumentation, and determination of particle concentration. Excluded are studies on the chemical analysis of particles. (This updated bibliography contains 225 abstracts, 12 of which are new entries to the previous edition.)

  11. Regulation mechanisms of the FLT3-ligand after irradiation; Mecanismes de regulation du FLT3-ligand apres irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Prat-Lepesant, M

    2005-06-15

    The hematopoietic compartment is one of the most severely damaged after chemotherapy, radiotherapy or accidental irradiations. Whatever its origin, the resulting damage to the bone marrow remains difficult to evaluate. Thus, it would be of great interest to get a biological indicator of residual hematopoiesis in order to adapt the treatment to each clinical situation. Recent results indicated that the plasma Flt3 ligand concentration was increased in patients suffering from either acquired or induced aplasia, suggesting that Flt3 ligand might be useful as a biological indicator of bone marrow status. We thus followed in a mouse model as well as in several clinical situations the variations in plasma Flt3 ligand concentration, after either homogeneous or heterogeneous irradiations. These variations were correlated to the number of hematopoietic progenitors and to other parameters such as duration and depth of pancytopenia. The results indicated that the concentration of Flt3 ligand in the blood reflects the bone marrow status, and that the follow-up of plasma Flt3 ligand concentration could give predictive information about the bone marrow function and the duration and severity of pancytopenia and thrombocytopenia. Nevertheless, the clinical use of Flt3 ligand as a biological indicator of bone marrow damage require the knowledge of the mechanisms regulating the variations in plasma Flt3 ligand concentration. We thus developed a study in the mouse model. The results indicated that the variations in plasma Flt3 ligand variations were not solely due to a balance between its production by lymphoid cells and its consumption by hematopoietic cells. Moreover, we showed that T lymphocytes are not the main regulator of plasma Flt3 ligand concentration as previously suggested, and that other cell types, possibly including bone marrow stromal cells, might be strongly implicated. These results also suggest that the Flt3 ligand is a main systemic regulator of hematopoiesis, especially during induced bone marrow aplasia. (author)

  12. Margin for In-Vessel Retention in the APR1400 - VESTA and SCDAP/RELAP5-3D Analyses

    Energy Technology Data Exchange (ETDEWEB)

    Joy Rempe; D. Knudson

    2004-12-01

    If cooling is inadequate during a reactor accident, a significant amount of core material could become molten and relocate to the lower head of the reactor vessel, as happened in the Three Mile Island Unit 2 (TMI-2) accident. If it is possible to ensure that the lower head remains intact so that relocated core materials are retained within the vessel, the enhanced safety associated with such plants can reduce concerns about containment failure and associated risk. For example, the enhanced safety of the Westinghouse Advanced 600 MWe pressurized water reactor (PWR) (AP600), which relied upon external reactor vessel cooling (ERVC) for in-vessel retention (IVR), resulted in the U.S. Nuclear Regulatory Commission (USNRC) approving the design without requiring certain conventional features common to existing light water reactors (LWRs). IVR of core melt is therefore a key severe accident management strategy adopted by some operating nuclear power plants and proposed for some advanced LWRs. However, it is not clear that currently proposed ERVC without additional enhancements could provide sufficient heat removal for higher-power reactors (up to 1500 MWe). Hence, a three-year, United States (U.S.) -Korean International Nuclear Energy Research Initiative (INERI) project was initiated in which the Idaho National Engineering and Environmental Laboratory (INEEL), Seoul National University (SNU), Pennsylvania State University (PSU), and the Korean Atomic Energy Research Institute (KAERI) explored options, such as enhanced ERVC performance and an enhanced in-vessel core catcher (IVCC), that have the potential to ensure that IVR is feasible for higher power reactors.

  13. Après le spectacle : les impacts psychosociaux de consommation de pornographie homosexuelle masculine chez les hommes gais

    Directory of Open Access Journals (Sweden)

    SIMON CORNEAU

    2010-01-01

    Full Text Available Cette recherche qualitative exploratoire vise à mettre à jour les impacts psychosociaux possibles de consommation de pornographie homosexuelle masculine à travers les discours de 20 usagers gais de Toronto (Canada. La consommation de pornographie semble plus acceptée et normalisée chez les hommes gais que chez les hommes hétérosexuels. Une telle consommation peut avoir une incidence sur certains aspects de la santé sexuelle et de la santé mentale. L'analyse thématique du corpus de nos données nous révèle que les impacts peuvent se faire sentir au niveau de l'apprentissage, de l'édification de la fantasmatique, de la validation de la sexualité entre hommes, de l'ingérence dans la vie sexuelle et enfin, sur l'habituation et sur l'image de soi/image corporelle. À l'aide de l’analyse critique de discours, nous avons pu documenter les discours sociaux plus larges en jeu dans les récits des usagers et voir de quelle façon ils se positionnent à l'intérieur de ces mêmes discours.

  14. Sensors and sensor systems for guidance and navigation II; Proceedings of the Meeting, Orlando, FL, Apr. 22, 23, 1992

    Science.gov (United States)

    Welch, Sharon S. (Editor)

    1992-01-01

    Topics discussed in this volume include aircraft guidance and navigation, optics for visual guidance of aircraft, spacecraft and missile guidance and navigation, lidar and ladar systems, microdevices, gyroscopes, cockpit displays, and automotive displays. Papers are presented on optical processing for range and attitude determination, aircraft collision avoidance using a statistical decision theory, a scanning laser aircraft surveillance system for carrier flight operations, star sensor simulation for astroinertial guidance and navigation, autonomous millimeter-wave radar guidance systems, and a 1.32-micron long-range solid state imaging ladar. Attention is also given to a microfabricated magnetometer using Young's modulus changes in magnetoelastic materials, an integrated microgyroscope, a pulsed diode ring laser gyroscope, self-scanned polysilicon active-matrix liquid-crystal displays, the history and development of coated contrast enhancement filters for cockpit displays, and the effect of the display configuration on the attentional sampling performance.

  15. Trente ans après l'arbre des causes : ergonomie et bien-être au travai

    OpenAIRE

    Grosjean, Vincent

    2009-01-01

    International audience Ergonomics in France has recently begun to focus on psychosocial risks. This disciple tends to favor angles of approach different from the approaches typically found in the literature. The safety practice could benefit from this renewed approach. As far as the prevention of occupational risks is concerned, another approach of French origin has had a strong impact. This is the fault tree analysis, popularized by the french Institute for Research and Safety (INRS) sinc...

  16. Digues et polders littoraux : réflexions après la tempête Xynthia

    Directory of Open Access Journals (Sweden)

    Fernand Verger

    2011-06-01

    Full Text Available Les digues de polders littoraux comprennent plusieurs catégories : digues de mer, digues de rebras, digues dormantes et digues ruinées. Dans le marais Poitevin, la tempête Xynthia, pendant laquelle la mer a atteint un niveau exceptionnel, a submergé l'ensemble du réseau des digues. Elle a permis de prendre conscience de l'état du réseau des digues et de l'absence d'une ligne continue de digues dormantes d'un niveau suffisant pour limiter l'extension de l'inondation.Des solutions adoptées ailleurs en Europe, comme la transformation des polders en polders d'été ou la dépoldérisation n'ont pas été envisagées. La réparation à l'identique, avec un renforcement a été adoptée. D'une façon plus générale, des indices sont proposés pour aider à la gestion des polders littoraux. Ces indices doivent tenir compte de la valeur écosystémique des schorres dont la biodiversité et la productivité sont exceptionnelles. La nécessité de quantifier les enjeux – ce qui est certes difficile – apparaît d'autant plus nécessaire que la montée du niveau de la mer risque de contraindre une politique de maintien rigide du trait de côte à des investissements disproportionnés à long terme.Polder dikes coasts include several categories: sea dikes, sleeper dikes and devastated levees. In Marais Poitevin, during the storm Xynthia, the entire network of dikes has been flooded due to the exceptional level of the sea at that time. This situation has raised awareness of the status network of the current network of levees and of the lack of a continuous line of sleeper levees at a sufficient level to limit the extent of the flooding.Solutions adopted elsewhere in Europe, such as processing of the polders in summer polders or depolderization have not been considered. The decision has been taken to repair at the same and to reinforce the previous defences. In a more general way, the elaboration of indexes has been done to improve the management of coastal polders. These indexes should reflect the ecosystem value of salt marshes whose biodiversity and productivity are outstanding. Although it may be difficult, the necessity to assess the different issues is necessary indeed because the rising of the sea level may force to maintain rigid coastline at a disproportionate investment in the long term.

  17. Design, Implementation and Validation of the Three-Wheel Holonomic Motion System of the Assistant Personal Robot (APR

    Directory of Open Access Journals (Sweden)

    Javier Moreno

    2016-10-01

    Full Text Available This paper presents the design, implementation and validation of the three-wheel holonomic motion system of a mobile robot designed to operate in homes. The holonomic motion system is described in terms of mechanical design and electronic control. The paper analyzes the kinematics of the motion system and validates the estimation of the trajectory comparing the displacement estimated with the internal odometry of the motors and the displacement estimated with a SLAM procedure based on LIDAR information. Results obtained in different experiments have shown a difference on less than 30 mm between the position estimated with the SLAM and odometry, and a difference in the angular orientation of the mobile robot lower than 5° in absolute displacements up to 1000 mm.

  18. Le deuil des conjoints après un cancer : entre évaluation et expérience subjective

    OpenAIRE

    Fasse, Léonor,

    2013-01-01

    In 2011, in France, more than 147 525 men and women died through cancer. This disease doesn’t affect only the oldest: 41 000 untimely deaths, before 65 years, are caused by cancer (FRANCIM, InVS, CIRC). All these persons were supposed to live with a partner. Faced with the patient’s death, more or less sustainable psychological, physical or social upheavals will affect the spouse.The cancer patient’s relatives and family constitute one of the patient’s main sources of support throughout the d...

  19. Après Nous le Déluge? Direct Democracy and Intergenerational Conflicts in Ageing Societies

    OpenAIRE

    Ahlfeldt, Gabriel; Maennig, Wolfgang; Steenbeck, Malte

    2016-01-01

    To assess the likely effects of population ageing on the outcomes of direct democracy, we analyze the effect of age on voting decisions in public referenda. To this end, we provide the first quantitative review of the literature and a case study of the Stuttgart 21 referendum on one of the largest infrastructure projects in Germany. The evi-dence suggests that intergenerational conflicts arising from population ageing will likely be limited to areas in which the net present value differs part...

  20. La reconstruction des édifices religieux en Basse-Normandie après la Seconde Guerre mondiale

    Directory of Open Access Journals (Sweden)

    Alain Nafilyan

    2012-04-01

    Full Text Available L’étude entreprise aux fins de protection au titre des monuments historiques a permis d’établir une synthèse globale relative à la reconstruction des édifices religieux en la replaçant dans son contexte local historique et économique. L’analyse typologique a mis en lumière un grand éclatement formel offrant diversité et tâtonnement architectural, très caractéristiques des hésitations stylistiques dans l’architecture des années 1950. L’art du vitrail trouva une place privilégiée au travers d’une recherche toujours plus plastique et subtile autour de la diffusion de la lumière. La conclusion tentera d’apporter sous forme de synthèse une contribution à une légitime interrogation : peut-on parler d’un « style » de la reconstruction ?The study begun for the purposes of legal protection in conformance with ancient memorials allowed to establish synthetic material global relative to the reconstruction of the religious buildings by replacing it in its historic and economic local context. The typological analysis revealed a big formal explosion offering very characteristic, architectural variety and experimentation of the stylistic hesitances in the architecture of the 1950s. The art of stained-glass window making found a privileged position through research always more plastic around the lighting of the church. The conclusion will try to bring in the form of synthesis a contribution to a legitimate interrogation: can we speak about a « style » of the reconstruction?

  1. Disjonction symphysaire après un accouchement par voie basse dystocique: à propos d'un cas

    Science.gov (United States)

    Laadioui, Meriem; Slimani, Wafae; Jayi, Sofia; Alaoui, Fatimazahra Fdili; Bouguern, Hakima; Chaara, Hikmat; Melhouf, Moulay Aabdelilah

    2014-01-01

    La disjonction symphysaire est une affection rare, qui se définie par un élargissement au niveau de l'articulation inter-symphysaire estimé supérieur à 10 mm. Cette affection nécessite une prise en charge spécialisée en cas de douleurs sévères et invalidantes. Nous rapportant le cas d'une patiente présentant des douleurs pelviennes intense avec impotence du MI gauche à J2 d'un accouchement dystocique, l'examen clinique a objectivé une douleur exquise à la palpation de la symphyse pubienne. Le diagnostic a été confirmé par une radiologie du bassin de face objectivant un élargissement de la symphyse pubienne de 15 mm, la prise en charge thérapeutique a consisté en une mise sous décharge et anti-coagulation préventive avec un traitement antalgique à base de paracétamol et AINS. L’évolution était favorable. A travers notre cas, nous insisterons sur les caractéristiques de cette pathologie notamment pronostic, ce qui permettra au praticien de comprendre l'intérêt du diagnostic et prise en charge précoce de cette entité qu'elle évoquer devant toute douleurs pelviennes survenant au cours de la grossesse ou en post partum. PMID:24932344

  2. Columbus VIII - Symposium on Space Station Utilization, 8th, Munich, Germany, Mar. 30-Apr. 4, 1992, Selected Papers

    Science.gov (United States)

    1993-03-01

    The symposium includes topics on the Columbus Programme and Precursor missions, the user support and ground infrastructure, the scientific requirements for the Columbus payloads, the payload operations, and the Mir missions. Papers are presented on Columbus Precursor Spacelab missions, the role of the APM Centre in the support of Columbus Precursor flights, the refined decentralized concept and development support, the Microgravity Advanced Research and Support (MARS) Center update, and the Columbus payload requirements in human physiology. Attention is also given to the fluid science users requirements, European space science and Space Station Freedom, payload operations for the Precursor Mission E1, and the strategic role of automation and robotics for Columbus utilization. Other papers are on a joint Austro-Soviet space project AUSTROMIR-91; a study of cognitive functions in microgravity, COGIMIR; the influence of microgravity on immune system and genetic information; and the Mir'92 project. (For individual items see A93-26552 to A93-26573)

  3. Infrared focal plane array producibility and related materials; Proceedings of the Meeting, Orlando, FL, Apr. 20, 21, 1992

    Science.gov (United States)

    Balcerak, Ray; Pellegrini, Paul W.; Scribner, Dean A.

    The present conference discusses the commercial diversification of the U.S. IR detector industry's commercial diversification, HgCdTe focal-plane array (FPAs) manufacture, LPE of (Hg,Cd)Te FPAs, uncooled IR FPA detector producibility, a high performance staring IR camera, and novel technologies for FPA dewars. Also discussed are hybridizing FPAs, cryoprober test development, HgCdTe on Si for monolithic focal plane arrays, popcorn noise in linear InGaAs detector arrays, and the use of narrowband laser speckle for MTF characterization of CCDs. (No individual items are abstracted in this volume)

  4. Infrared detectors and focal plane arrays II; Proceedings of the Meeting, Orlando, FL, Apr. 23, 24, 1992

    Science.gov (United States)

    Dereniak, Eustace L.; Sampson, Robert E.

    The present conference discusses Schottky-barrier IR image sensors, SWIR and MWIR Schottky-barrier imagers, a 640 x 640 PtSi, models of nonlinearities in focal plane arrays, retinal function relative to IRT focal plane arrays, a solid-state pyroelectric imager, and electrolyte electroreflectance spectroscopies for the ion-implanted HgCdTe with thermal annealing. Also discussed are HgCdTe hybrid focal plane arrays for thermoelectrically cooled applications, a novel IR detector plasma-edge detector, and IR detector circuits using monolithic CMOS amps with InSb detectors. (No individual items are abstracted in this volume)

  5. Chernobyl in the French mass media 14 years after the accident; Tchernobyl dans la presse francaise 14 ans apres

    Energy Technology Data Exchange (ETDEWEB)

    Anon

    2001-02-01

    The author presents how the mass media have dealt with the fourteenth anniversary of the Chernobyl accident. Nowadays Chernobyl epitomizes the hazards of nuclear energy. Public opinion has become extremely sensitive to topics concerning human health. This sensitivity is due to previous important affairs such as the scandal of the tainted blood, the mad cow disease or the syndrome of the Balkan war. Most media have broadened the debate to the sanitary impact of nuclear activities. The hyper-mediatization of the legal case of a man prosecuting the French state for no having taken adequate measures when the radioactive cloud spread over France, has given the feeling that French authorities have always wrongly minimized the consequences of the accident. (A.C.)

  6. Synthesis report about the after-mine mission; Rapport de synthese sur la mission apres-mine

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    The French ministry of economy finances and industry has assigned the mission of evaluating the after-mine management system to the general inspection of finances and the general council of mines. The after-mine management system encompasses all procedures of coal, iron and potash mines closing down, land reclamation and environmental remedial action and site rehabilitation. This document makes first a status of the problems generated by the stoppage of mining activities: technical aspects, costs, institutional, organisational and juridical aspects, conservation of competences, international benchmarking elements and good practices implemented in foreign countries. Then, in a second part, this report presents the recommendations of the after-mine mission about the mastery of after-mine costs in agreement with the respect of the technical and social goals, with the development of the after-mine institutional system with the scheduled disappearance of Charbonnages de France and Mines de Potasses d'Alsace companies, and with the conservation of competences in the framework of the post-mine operational structure proposed by the mission. (J.S.)

  7. Mettre en oeuvre une GMAO maintenance industrielle, service après-vente, maintenance immobilière

    CERN Document Server

    Frédéric, Marc

    2003-01-01

    Pour les entreprises, l'utilisation d'un progiciel de GMAO [Gestion de la Maintenance Assistée par Ordinateur] est devenue un outil incontournable de gestion technico-budgétaire des activités de maintenance. Cependant, sans une bonne prise en compte des besoins techniques, financiers et humains, l'implantation d'un logiciel de GMAO risque de conduire à des échecs coûteux et aux effets irréversibles. Cet ouvrage très pratique propose donc de passer en revue toutes les étapes de la mise en œuvre d'une GMAO, de l'analyse des besoins jusqu'aux impacts organisationnels, en donnant tous les éléments permettant la réussite d'un projet d'implantation de GMAO.

  8. Study on thermal-hydraulic phenomena in porous media. Summarized report from 1997 Apr. to 2000 Mar

    International Nuclear Information System (INIS)

    This study deals with thermal-hydraulic phenomena in a porous blockage of a Fast Breeder Reactor. When foreign substances flow into the fuel subassembly with wire spacer, they would choke up the sub-channel and form a porous blockage. The objective of this study is to clarify the thermal-hydraulic phenomena in porous media and to develop the analytical method to predict the thermal-hydraulic field, deciding the maximum temperature on the fuel pin surface. This study is performed in cooperation with University of Tsukuba and Japan Nuclear Cycle Development Institute (JNC) from November 1997 to March 2000. This report describes the results for three years from April 1997 to March 2000. The visualization method using NaI solution as working fluid and Pyrex grass as structure was applicable to the porous media flow. When the concentration of NaI is 56.9 [wt%] in the solution, the refraction-rate corresponds to that of the Pyrex grass. The experiments to measure the velocity field inside and outside the blockage with Particle Image Velocimetry (PIV) analysis and Laser Doppler Velocimetry (LDV) were conducted. Moreover, we tried to measure the fluid temperature inside the blockage in the NaI solution, using Laser Induced Fluorescence (LIF) method. We checked the relation between the brightness of the fluorescence and solution temperature. And then, we revealed that the LIF method could be used even in the NaI solution. We also conducted the numerical analysis for the experiments. We confirmed that the calculation using the porous boby model is applicable to the analysis of the flow behavior around the porous blockage. (author)

  9. LHC Beam Splash seen by the ATLAS detector - 5 Apr 2015 - Run 260272 - LB 240 - event 5879

    CERN Multimedia

    ATLAS EXPERIMENT

    2015-01-01

    Event display of first collimator "splash" event seen by the ATLAS experiment in LHC Run-2 , on Sunday April the 5th : event 5879, run 260272. The collimator position is 140m in front of the ATLAS interaction point. The spray of particles enters ATLAS from the right hand side of the picture.

  10. Représentation de l'espace gaulois d'après Grégoire de Tours

    Directory of Open Access Journals (Sweden)

    Xavier Rodier

    2004-12-01

    Full Text Available The systematic mapping of place names in Gaul from the collected works of Gregory of Tours (late 6th century stimulated some thoughts on the modern representation of space for this period. Different cartographic tools were employed to transform the distribution of location points into a spatial image. Lastly, the proposed virtual map provides the possibility to travel around this created space and explore it. While this virtual map generated new perspectives regarding the database of Gregory, it also showed the limited use one can make of this information regarding space.

  11. Liberalisation de la filiere coton en Côte d'Ivoire quinze ans apres : empreinte spatiale et organisationnelle

    Directory of Open Access Journals (Sweden)

    SIMPLICE YAO KOFFI

    2013-08-01

    Full Text Available The liberalization of the cotton sector in Ivory Coast after fifteen years: spatial and organizational marks. The liberalization of the cotton sector in Ivory Coast is inspired by industrialized countries. Its approaches are supported by the Breton Woods institutions and the French Cooperation. The aim of this study is to review spatial and organizational reforms in the cotton basin of Ivory Coast. The results of this research revealed that liberalization is the cause of the restructuring of the cotton area. On the other hand, it has resulted an organizational dynamic based on the activity of the cotton companies and producers. In addition, the areas defined by the liberalization are not respected by cotton agencies. This non-compliance is manifested by the incursion of cotton companies in areas outside their initial block. In this logic of incursion, the producers of public society (CIDT produce significantly more than those supervised by private cotton companies. This observation raises a debate regarding the continued liberalization of the cotton sector in Ivory Coast.

  12. LHC Beam Splash seen by the ATLAS detector - 7 Apr 2015 - Run 260466 - LB 731 - Event 16848

    CERN Multimedia

    ATLAS, EXPERIMENT

    2015-01-01

    Event display of a collimator "splash" event seen by the ATLAS experiment in LHC Run-2, on Tuesday April the 7th 2015: event 16848, run 260466. The collimator position is 140m in front of the ATLAS interaction point. The figure on the left shows an axial view of the various components of the ATLAS detector. The figure on the right shows the energy deposits in the cells of the ATLAS calorimeter.

  13. Gesellschaft fuer angewandte Mathematik und Mechanik, Scientific Annual Meeting, Technische Universitaet Wien, Vienna, Austria, Apr. 5-9, 1988, Reports

    Science.gov (United States)

    Various papers on applied mathematics and mechanics are presented. The general topics considered include: numerical treatment of implicit differential equations and differential algebraic systems; software for scientific calculation; structural analysis and simulation; stochastic methods; biomathematics; interpolation and approximation; quadrature; optimization; methods in operations research; enclosures for linear and nonlinear equations; enclosures for functional equations; ordinary differential equations and dynamical systems; ordinary differential and difference equations; and numerics of stiff differential equations. Also addressed are: waves, analysis, applications, and numerics in partial differential equations; large systems of linear equations; multigrid methods; iterative processes in applied function theory; discrete mathematics and informatics; fundamentals, special methods, and shells in FEM; beams and special applications; fundamentals, solid mechanics, and fluid mechanics in BEM.

  14. APR-246/PRIMA-1MET rescues epidermal differentiation in skin keratinocytes derived from EEC syndrome patients with p63 mutations

    OpenAIRE

    Shen, Jinfeng; van den Bogaard, Ellen H.; Kouwenhoven, Evelyn N.; Vladimir J.N. Bykov; Rinne, Tuula; Zhang, Qiang; Tjabringa, Geuranne S.; Gilissen, Christian; Van Heeringen, Simon J.; Schalkwijk, Joost; Van Bokhoven, Hans; Wiman, Klas G.; Zhou, Huiqing

    2013-01-01

    p53 and p63 share extensive sequence and structure homology. p53 is frequently mutated in cancer, whereas mutations in p63 cause developmental disorders manifested in ectodermal dysplasia, limb defects, and orofacial clefting. We have established primary adult skin keratinocytes from ectrodactyly, ectodermal dysplasia, and cleft lip/palate (EEC) syndrome patients with p63 mutations as an in vitro human model to study the disease mechanism in the skin of EEC patients. We show that these patien...

  15. The laser and its uses: 50 years after its invention; Le laser et ses applications: 50 ans apres son invention

    Energy Technology Data Exchange (ETDEWEB)

    Besnard, P. [FOTON/ENSSAT, CNRS, 22 - Lannion (France); Favennec, P.N. [APAST, 22 - Lannion (France)

    2011-07-01

    The laser, 50 years after its invention, has become a major player in modern technologies with its efficient partner the optical fiber. This book reviews the numerous applications of laser in diverse fields such as telecommunication, metrology, optical radar, surface treatment, medicine. The last chapter is dedicated to inertial fusion through the presentation of the Megajoule laser (LMJ) project

  16. Radionuclide lymphoscintigraphy in limb edemas; La lymphoscintigraphie dans la pathologie lymphatique des membres: reflexions apres 20 ans d`utilisation

    Energy Technology Data Exchange (ETDEWEB)

    Pecking, A.P. [Centre Rene Huguenin, 92 - Saint-Cloud (France); Cluzan, R.V. [Hopital Cognacq-Jay, 75 - Paris (France)

    1997-12-31

    Indirect radionuclide lymphoscintigraphy is a safe, non-invasive and physiological method for the assessment of the limb lymphatic system. Colloids as antimony or rhenium sulphide labeled with 99m technetium have been widely used for morphological studies. Quantitative studies involving a continuous count rate monitoring of the injection sites followed by a computer analysis of dynamic image sequences have been a new promising step for an objective measurement of the peripheral lymphatic function. The injection site is always bilateral on the first web space of either the hand or the foot using a small volume (<0.2 mL) of the radiocolloid. This method has been validated on 30 young healthy volunteers and normal values established from a group of 125 upper and 141 lower limbs (normal subjects). The normal results showed a slight but continuous decrease in lymphatic function depending on the age of the subject. In pathological situations, we observed dysfunction of the lymphatic system in pure lymphoedemas or so-called lympho-venous edemas as demonstrated on the 1,182 upper and 2,463 lower limbs tested. The radionuclide lymphoscintigraphy may be helpful in cases of unilateral swollen limbs demonstrating a lymphatic dysfunction on a clinically normal contralateral limb at the first stage of a distal edema which appears within a few weeks or days, in a transient edema phase when normal status and oedema alternate. The lymphoscintigraphy gives objective and reproducible parameters necessary to assess the lymphatic variation under therapy (decongestive physiotherapy, surgery, drugs) and may be useful in the selection of new lympho-tonic treatments. This method is only reflecting the lymphatic function and is unable to appreciate the total lymphatic flow of the limb. Its results only reflect what happens at the injection site and it may be necessary to add a second test using a proximal injection in order to assess the occurrence of lymph nodes not visualized by the general method. (authors). 18 refs.

  17. Le dermatofibrosarcome de Darier et Ferrand, une tumeur cutanée particulière: à propos de 32 cas et revue de la littérature

    Science.gov (United States)

    Elamrani, Driss; Droussi, Hatim; Boukind, Samira; Elatiqi, Keltoum; Dlimi, Meriem; Benchamkha, Yassine; Ettalbi, Saloua

    2014-01-01

    Le dermatofibrosarcome (DFS) est une tumeur fibreuse de la peau, de croissance lente, à très haut risque de récidive locale, mais à potentiel métastatique faible. A partir d'une étude rétrospective étalée sur une période de 5 ans (décembre 2008 - décembre 2013), nous avons analysé les caractéristiques épidémiologiques et cliniques, le délai de diagnostic, le type de thérapeutique et le devenir de 32 patients présentant des tumeurs de Darier et Ferrand histologiquement prouvées. Parmi les 32 patients, 10 se sont présentés initialement au service pour une récidive tumorale. Une discrète prédominance masculine a été notée. Les DFS touchent préférentiellement l'adulte jeune. Le délai diagnostique observé est en moyenne de 4 ans. Le tronc est la localisation préférentielle (60%), suivi par les extrémités proximales (30%). Les 32 patients ont été traités par exérèse chirurgicale avec une marge de 5cm en surface, emportant en profondeur une barrière anatomique saine. La couverture de la perte de substance (PDS) a été réalisée après confirmation anatomopathologique du caractère carcinologique de l'exérèse, et a fait appel à différents moyens allant de la greffe cutanée aux lambeaux musculo –cutanés libres. L’évolution a été marquée par la survenue d'une récidive tumorale chez 8 patients (3 cas parmi les tumeurs vues en première intention et 5 cas parmi les tumeurs vues en récidive) et les résultats ont été jugés satisfaisants sur le plan esthétique et fonctionnel. Le DFS de Darier et Ferrand est une tumeur dont le pronostic et le risque évolutif sont principalement liés au délai diagnostic et la qualité de la première exérèse. Le diagnostic tardif, rend difficile la chirurgie d'exérèse et de reconstruction Les possibilités de guérison en cas de chirurgie primaire bien conduite sont significativement supérieures à celles d'une chirurgie de rattrapage. L'amélioration du pronostic passe par

  18. Lõbusalt üllatav Trash.dk / Christel Karits

    Index Scriptorium Estoniae

    Karits, Christel, 1966-

    2008-01-01

    Taani löökpillimängijate shõugrupi esinemistest 22. apr. Viljandi Pärimusmuusika Aidas, 23. apr. Jõhvi kontserdimajas, 24. apr. Tallinnas Estonia kontserdisaalis, 25. apr. Pärnu kontserdimajas ja 26. apr. VAnemuise kontserdimajas

  19. Uus valitsus kordab eelkäija vigu / Ivari Padar

    Index Scriptorium Estoniae

    Padar, Ivari, 1965-

    2005-01-01

    Ilmunud ka Nädaline 14. apr., lk. 4, Järva Teataja 14. apr., lk. 2, Põhjarannik 14. apr., lk. 2, Severnoje Poberezhje 14. apr., lk. 2, Koit 14. apr., lk. 6, Virumaa Teataja 15. apr., lk. 7, Vali Uudised 15. apr., lk. 2, Hiiu Leht 15. apr., lk. 2, Kuuulutaja 15. apr., lk. 4, Virumaa Nädlalaht 15. apr. lk. 3, Võrumaa Teataja 16. apr. lk. 2, Sakala 19. apr. lk. 2, Videvik 21. apr. lk. 3, Pärnu Postimees 6. mai lk. 15. Sotsiaaldemokraatide arvamus uuest valitsuslepingust

  20. Elame üheskoos kaua ja tervelt / Maret Maripuu

    Index Scriptorium Estoniae

    Maripuu, Maret, 1974-

    2008-01-01

    Ilmunud ka: Den za Dnjom 11. apr. lk. 18-19, Virumaa Teataja 18. apr., lk. 11, Harju Ekspress 18.apr., lk. 6, Harju Elu 18. apr., lk. 2, Türi Rahvaleht 18. apr. lk. 4, Põhjarannik 19. apr., lk. 2, Severnoje Poberezhje 19. apr. lk. 2. Sotsiaalministeeriumis valminud rahvastiku tervise arengukavast

  1. Schwannome benin primitif retrovesical: une tumeur très rare à propos d'un cas

    Science.gov (United States)

    Beddouche, Ali; Fahsi, Othemane; Kallat, Adil; El Bote, Hicham; Ziani, Idriss; El Sayegh, Hachem; Iken, Ali; Benslimane, Lounis; Nouini, Yassine

    2016-01-01

    Le schwannome est une tumeur le plus souvent bénigne, d'origine nerveuse se développant à partir des cellules de la gaine de Schwann. C'est une tumeur très rare tant par sa fréquence que par sa localisation rétrovésicale. L'examen anatomopathologique et immunohistochimique confirme le type histologique ainsi que le caractère bénin ou malin du schwannome. En raison des récidives, et du risque de transformation maligne, l'exérèse doit être complète. Nous rapportons le cas d'un patient âgé de 39 ans, admis pour une douleur pelvienne chronique à type de pesanteur, des signes irritatifs du bas appareil urinaire, et des troubles de transit. L'imagerie (échographie, TDM, IRM) a révélé la présence d'une masse pelvienne rétrovésicale, à paroi fine, latéralisée à gauche, mesurant 68x70x70 mm, exerçant un effet de masse sur la vessie et le sigmoïde. L'intervention chirurgicale menée par une laparotomie médiane a permis l'exérèse d'une masse retrovésicale bien encapsulée. L'examen anatomopathologique et immunohistochimique ont conclu à un schwannome bénin. La récidive et la transformation maligne bien que rare après chirurgie impose une surveillance post opératoire clinique et tomodensitométrique annuelle. PMID:27217902

  2. L'endométriose de la paroi abdominale: à propos d'un cas rare

    Science.gov (United States)

    Jayi, Sofia; Laadioui, Meriem; Bouguern, Hakima; Chaara, Hikmat; Melhouf, Aabdelilah

    2013-01-01

    L'endométriose de la paroi est une entité clinique rare, dont la physiopathologie demeure imprécise. Elle survient le plus souvent après une intervention chirurgicale gynécologique ou obstétricale. Nous rapportons le cas d'une patiente présentant une douleur cyclique, au niveau de la cicatrice de césarienne. Avec à l'examen clinique une masse de 3 cm localisée au niveau de la fosse iliaque droite. L'échographie-doppler a objectivé une image d'allure tissulaire, polylobée, à vascularisation centrale, mesurant 32/16 mm, évoquent une masse endométriosique ou une tumeur des parties molles. D'où la décision d'excision de la lésion, au cours de laquelle on a découvert une masse dure de 3/2 cm, en sous aponévrotique accolée au muscle grand droit de l'abdomen. L'étude anatomopathologique a confirmé le diagnostic d'endométriose pariétale. Les suites postopératoires étaient simples avec un recul de 2 ans et demie sans récidive de la masse ni de la douleur. A travers notre cas, nous insisterons sur les caractéristiques de cette pathologie notamment pronostic, ce qui permettra au praticien de comprendre l'intérêt du diagnostic et prise en charge précoce de cette entité - pour laquelle on ne pense jamais assez devant une masse pariétale - et de sa prévention au cours de chaque chirurgie gynécologique ou obstétricale. PMID:24171068

  3. Evaluation of an indirect enzyme-linked immunosorbent assay (ELISA) for detection of antibodies to the Apx toxins of Actinobacillus pleuropneumoniae

    DEFF Research Database (Denmark)

    Nielsen, Ragnhild; van den Bosch, Johannes F.; Plambeck, Tamara;

    2000-01-01

    The reference strains of the 12 serotypes of Actinobacillus pleuropneumoniae express one or two of three different RTX exotoxins designated Apr I, Apr II and Apr III. The toxins are important virulence factors. In the present study, ELISAs with purified Apr I, Apr II and Apr III, respectively, as...... of exotoxin is not revealed serologically in the ELISA test.......The reference strains of the 12 serotypes of Actinobacillus pleuropneumoniae express one or two of three different RTX exotoxins designated Apr I, Apr II and Apr III. The toxins are important virulence factors. In the present study, ELISAs with purified Apr I, Apr II and Apr III, respectively...

  4. Pidamata jäänud kõne / Imre Sooäär

    Index Scriptorium Estoniae

    Sooäär, Imre, 1969-

    2007-01-01

    Ilmunud ka: Lääne Elu, 10. apr. 2007, lk. 2; Hiiu Leht, 10. apr. 2007, lk. 2; Põhjarannik, 10. apr. 2007, lk. 2; Severnoje Poberezhje, 10. apr. 2007, lk. 2; Harjumaa, 10. apr. 2007, lk. 2; Virumaa Teataja, 12. apr. 2007, lk. 11; Nädaline, 12. apr. 2007, lk. 2; Sakala, 13. apr. 2007, lk. 2; Harju Ekspress, 13. apr. 2007, lk. 6; Vali Uudised, 13. apr. 2007, lk. 2; Järva Teataja, 14. apr. 2007, lk. 2; Vooremaa, 14. apr. 2007, lk. 2. Parlamendiliige leiab, et Ene Ergma oli parim Riigikogu XI koosseisu kandidaat spiikri kohale

  5. Le mélanome malin: une tumeur rare des fosses nasales - à propos d'une série de 10 cas

    Science.gov (United States)

    Errachdi, Amal; Epala, Brice Nkoua; Asabbane, Amal; Kabbali, Naoual; Hemmich, Mariem; Kebdani, Tayeb; Benjaafar, Noureddine

    2014-01-01

    Le mélanome malin des fosses nasales est une tumeur rare mais très agressive, de traitement complexe et de pronostic défavorable. Son traitement relève en principe d'une prise en charge essentiellement chirurgicale complétée par une radiothérapie. L'objectif de ce travail est de rapporter les caractéristiques cliniques, thérapeutiques et évolutives des mélanomes des fosses nasales. Nous avons analysé rétrospectivement 10 cas de mélanomes des fosses nasales suivis à l'institut national d'oncologie de Rabat. La rhinoscopie avec biopsie a permis la confirmation histologique du diagnostic de mélanome. Le bilan d'extension comprenait une tomodensitométrie ou imagerie par résonnance magnétique du massif facial, une radiographie thoracique et une échographie abdominale. Dans notre série, l’âge médian était de 67.5 ans, avec une prédominance féminine (7femmes et 3hommes). Le délai médian de découverte était de 6 mois. Deux patients étaient métastatiques d'emblée, et toutes les tumeurs étaient localement avancées au moment du diagnostic. Sept patients ont été opérés avec des limites chirurgicales envahies dans 2 cas et 3 patients étaient inopérables. 2 patients ont été irradiés après la chirurgie et 2 patients ont reçu une chimiothérapie arrêtée au moment de la progression. Deux patients ont récidivé après traitement, et un patient était en mauvais état général et a bénéficié uniquement de soins palliatifs. Tous les patients sont décédés avec un délai médian de survie de 12 mois. Le mélanome malin muqueux des fosses nasales, bien que rare, demeure une pathologie de pronostic défavorable et pose des problèmes de prise en charge. PMID:25404963

  6. MFE和APR地层测试器应用技术探讨%Discuss for Applied Technology of MFE and APR Formation Tester

    Institute of Scientific and Technical Information of China (English)

    李加明

    2010-01-01

    通过对MFE、APR两种测试工具的结构、原理和工作特性的剖析,结合现场使用情况,对测试作业过程中遇到的封隔器失封、开关井不正常等问题进行了分析和探讨,运用力学原理分析了封隔器受力状态和测试操作力学.根据不同井况特点,有针对性地提出了应对措施和建议,为合理选用MFE、APR地层测试工具,组配合适的测试管柱结构提供了依据.

  7. L’histoire de l’architecture et du design au XIXe siècle : avant et après l’authenticité

    OpenAIRE

    Muthesius, Stefan

    2008-01-01

    Historians of architecture and the applied arts in the late nineteenth century developed a peculiar notion of a borderline around 1840: before that date, they maintained, designing and building was done largely unconsciously, entailing a ‘true’ ethnicity of design, especially of workmanship, and styles emerged somehow authentically from the broadest national or regional groups - whereas from 1840 onwards everything was done consciously and artificially. The article discusses the emergence of ...

  8. Numerical Analysis of In-vessel Retention using MARS-Ga for APR 1400 under the gallium-water External Reactor Vessel Cooling System

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Sarah; Park, Seong Dae; Kim, In Guk; Bang, In Cheol [Ulsan National Institute of Science and Technology, Ulsan (Korea, Republic of)

    2015-05-15

    The numerical analyses results show that the temperature range of the liquid gallium is much lower than its boiling point and the natural convection can be confirmed. Because liquid gallium does not have the phase change unlike water, the gallium-water IVR-ERVCS can provide the stable and reliable cooling capability. To solve the limitation of IVR-ERVCS on the critical heat flux and ensure the sufficient thermal margin, it is confirmed that the gallium-water IVR-ERVCS can be a successful severe accident mitigation strategy in nuclear power plants. The gallium-water IVR-ERVCS consists of the liquid metal and water in terms of coolants. The decay heat generated in corium is transferred to liquid metal, gallium through the reactor pressure vessel and then removed from the water pool as an ultimate heat sink. In this research, the configuration for numerical simulation is the side cooling concept that two fluids (liquid gallium and water) were separated by the block structure like so-called liquid metal catcher. Compared to the existing system, the block system was added instead of the cavity wall. To analyze the gallium-water IVR-ERVCS, the MARS-Ga code with the gallium properties is used.

  9. Le personnage du Christ dans les Mystères anglais : une analyse d'après les travaux de Victor Turner

    Directory of Open Access Journals (Sweden)

    Tatjana Silec

    2010-06-01

    Full Text Available Dans les Mystères de York ou de Towneley, le Christ tient à la fois du fou de cour et du fou sage, ce qui peut sembler paradoxal mais trouve son origine dans la place accordée au fou dans la société médiévale occidentale en général. Le fou dit « sage » était, en raison du mépris dans lequel il tenait sa propre personne physique et son statut social, couvert du même opprobre que son homonyme de cour: tous deux bénéficiaient d'une liberté singulière qu'ils payaient de l'abandon de toute dignité. Les brimades endurées par le Christ dans deux Mystères anglais, Christ Before Herod et The Buffeting1, qui visent, pour les bourreaux, à humilier leur victime en faisant d’elle un bouffon, ont pour objet véritable de rendre évidente la folie d'un tel geste aux yeux des spectateurs, ainsi que le courage du Christ dans une mise en scène qui met en avant les qualités liminales de cette période de la vie du fils de Dieu, lequel est amené à devenir roi au terme de celle-ci. Elles mettent également en évidence le statut véritablement abject du fou professionnel.In the mystery cycles of York and Towneley, Jesus Christ is compared to a jester or a (wise fool by his opponents, something which is not so surprising if one takes into account the place given to the fool in medieval society. Indeed, despite his “wisdom” and because of his traditional lack of regard for his own person or status, the wise fool was the regular target of the same sort of abuse that the professional jester incurred, for it was the price they both had to pay for the special type of freedom they were awarded. The humiliations that Christ is subjected to in Christ Before Herod and The Buffeting, which his tormentors use to ridicule him, are evidence of their own folly and a testament to their victim’s fortitude. They exhibit the liminal qualities described by Turner in his analysis of the ritual process. And they are also a reminder of the truly abject condition of the professional fool.Nei misteri di York et di Towneley, il Cristo è rappresentato contemporaneamente come un buffone di corte e come un folle sapiente, cosa che può apparire paradossale ma le cui origini sono da rinvenirsi nel ruolo accordato al folle nella società medievale più in generale. Il folle detto «sapiente» era, a causa del disprezzo causato dalla sua fisicità e dal suo statuto sociale, oggetto della stessa considerazione riservata al suo omologo cortigiano: entrambi beneficiavano di una straordinaria libertà, pagata al prezzo della rinuncia ad ogni dignità. Le umiliazioni di cui è oggetto il Cristo in Christ Before Herod e The Buffeting, che lo riducono al rango di buffone, hanno la funzione di rendere manifesta la pazzia di un tale gesto agli occhi degli spettatori, ed insieme il coraggio del Cristo in una messa in scena que sottolinea le qualità liminari di questa fase della vita del figlio di Dio, destinato a divenire re al termine di questo processo. Analogamente, manifestano l’abiezione dello statuto del folle di professione.

  10. Management of inflammatory breast cancer after neo-adjuvant chemotherapy; Traitement locoregional du cancer du sein inflammatoire apres chimiotherapie neo-adjuvante

    Energy Technology Data Exchange (ETDEWEB)

    Abrous-Anane, S.; Daveau, C.; Dendale, R.; Campana, F.; Kirova, Y.; Fourquet, A.; Bollet, M.A. [Service d' onco-radiotherapie, institut Curie, 26, rue d' Ulm, 75005 Paris cedex 05 (France); Savignoni, A.; Gautier, C. [Service de biostatistique, institut Curie, 26, rue d' Ulm, 75248 Paris cedex 05 (France); Pierga, J.Y. [Service d' oncologie medicale, institut Curie, 26, rue d' Ulm, 75248 Paris cedex 05 (France); Reyal, F. [Service de chirurgie, institut Curie, 26, rue d' Ulm, 75248 Paris cedex 05 (France)

    2011-12-15

    Purpose. - To assess the benefit of breast surgery for inflammatory breast cancer. Patients and methods. - This retrospective series was based on 232 patients treated for inflammatory breast cancer. All patients received primary chemotherapy followed by either exclusive radiotherapy (118 patients, 51%) or surgery with or without radiotherapy (114 patients, 49%). The median follow-up was 11 years. Results. - The two groups were comparable apart from fewer tumors smaller than 70 mm (43% vs 33%, P = 0.003), a higher rate of clinical stage N2 (15% vs 5%, P = 0.04) and fewer histopathological grade 3 tumors (46% vs 61%, P < 0.05) in the no-surgery group. The addition of surgery was associated with a significant improvement in locoregional disease control (P = 0.04) but with no significant difference in overall survival rates or disease-free intervals. Late toxicities were not significantly different between the two treatment groups except for a higher rate of fibrosis in the no-surgery group (P < 0.0001), and more lymphedema in the surgery group (P = 0.002). Conclusion. - Our data suggest an improvement in locoregional control in patients treated by surgery, in conjunction with chemotherapy and radiotherapy, for inflammatory breast cancer. (authors)

  11. Contrôle des circuits auxiliaires des P.F.W. (arret machine 2004/2006, après rénovation de 25 aimants)

    CERN Document Server

    Ottaviani, J

    2006-01-01

    Les PFW sont des nappes polaires installées sur les pôles des aimants du PS. Elles sont au nombre de 4 par unité d'aimant et constituées d'un circuit principal (dans lequel circule le courant désiré selon le cycle magnétique utilisé) et de circuits auxiliaires. Les circuits auxiliaires sont des enroulements de correction (boucles de tour et ?pick-up? brasés sur les enroulements principaux). Pendant la variation du champ magnétique de l'aimant PS, on utilise des tensions induites dans ces circuits auxiliaires pour corriger les erreurs de champ dues aux pertes par courants de Foucault dans la chambre à vide. Chaque année, pendant l'arrêt machine, on vérifie si les caractéristiques des circuits auxiliaires correspondent aux normes (mesures des résistances des boucles de tours, résistances entre ?pick-up? et isolation des circuits) afin de faire un suivi. Des mesures ont été faites au début du grand arrêt en décembre 2004 afin de définir quels aimants seraient à rénover (l'état des PFW e...

  12. L'impact des transformations de régime en Pologne après 1989 sur la définition du droit rural

    Directory of Open Access Journals (Sweden)

    Aleksander Lichorowicz

    2015-01-01

    Full Text Available Le débat sur la portée et les criteres de définition du droit rural continue, dans la doctrine polonaise, depuis les années cinquante. J'ai présenté son déroulement et ses résultats dans une vaste dissertation il y a plusieurs années (...

  13. Evaluation of immediate breast reconstruction and radiotherapy: Factors associated with complications; Reconstruction mammaire immediate apres mastectomie suivie de radiotherapie: facteurs de risque de complications

    Energy Technology Data Exchange (ETDEWEB)

    Gross, E.; Cowen, D. [Departement de radiotherapie, hopital de la Timone, 13 - Marseille (France); Hannoun-Levi, J.M. [Departement de radiotherapie, centre Antoine-Lacassagne, 06 - Nice (France); Rouanet, P. [Departement de chirurgie, centre Val-d' Aurelle-Paul-Lamarque, 34 - Montpellier (France); Houvenaeghel, G. [Departement de chirurgie, institut Paoli-Calmettes, 13 - Marseille (France); Teissier, E. [Centre azureen de cancerologie, 06 - Mougins (France); Ellis, S. [Centre catalan d' oncologie, 66 - Perpignan (France); Resbeut, M. [Centre de radiotherapie Saint-Louis, 83 - Toulon (France); Tallet, A. [Departement de radiotherapie, institut Paoli-Calmettes, 13 - Marseille (France); Vaini Cowen, V. [Departement de chirurgie gynecologique, polyclinique du Parc-Rambot, 13 - Aix-en-Provence (France); Azria, D. [Departement de radiotherapie, centre Val-d' Aurelle-Paul-Lamarque, 34 - Montpellier (France)

    2010-12-15

    Objectives: To determine prospectively the factors associated with reconstruction failure (i.e. requiring expander removal) and capsular contracture in patients undergoing mastectomy and immediate two-stage breast reconstruction with a tissue expander and implant, and radiotherapy for breast cancer. This is a multi-institutional prospective non-randomized trial. Patients and Methods: Between 2/1998 and 9/2006, we prospectively evaluated 141 consecutive patients who received 141 implants after mastectomy and underwent chest wall radiotherapy (46 to 50 Gy in 23 to 25 fractions). Patients were evaluated after 24 to 36 months by two senior physicians (radiation oncologist and surgeon). Results: Medical follow-up was 37 months. Baker 1 and 2 capsular contracture was observed in 67.5% of patients, Baker 3 and 4 in 32.5%. There were 32 reconstruction failures. In a univariate analysis, the following factors were associated with Baker 3 and 4 capsular contracture: surgeon, use of hormonotherapy and smoking, of which only one remained in the multivariate analysis: surgeon. In a univariate analysis, the following factors were associated with reconstruction failure: tumor size T3 or T4, smoking, pN+ axilla. Three factors remained associated with reconstruction failure in a multiple logistic regression: large tumors T3/T4, smoking and pN+ axilla. Conclusions: Mastectomy, radiotherapy and immediate breast reconstruction with a tissue expander and implant should be considered when breast conserving surgery has been denied. Adequate patients can be easily selected by using three factors of favourable outcome. (authors)

  14. Chernobylsk: twenty years later, the international system of nuclear civil liability; Tchernobyl: 20 ans apres, le systeme international de responsabilite civile nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Lahorgue, M.B. [Poitiers Univ., 86 (France)

    2006-06-15

    The International system of nuclear civil liability is based on two international treaties: the Paris convention (24.07.1960) and the Brussels convention (31.01.1963), with a time limit for ratification in each concerned country at 30.10.1968. The Paris convention treats compensation and transfrontier problems, the amount of compensation is limited, the Brussels convention specifies the financial system of compensation. The Vienna system under the IAEA auspices gives minimal norms of financial protection against damages and stood in may 1963 thirty three parties signed it. Hungary, Poland, Lithuania, Romania, Armenia, czech republic, Estonia, Bulgaria, Slovakia, Latvia, Ukraine, Belarus, Moldavia have joined the Vienna convention, then the Russian Federation that had signed the Convention in 1996 became member in august 2005. New elements appear such measures of remedial action or measures of prevention of reduction of nuclear damages are included, the new protocol increases the geographical area by taking into account the maritime areas because of the evolution of the international sea law. The transport needs specific contracts between parties, the only case of exoneration is the armed conflicts, civil war, insurrection. The time of loss of right comes from ten years to thirty years, for deaths and body damages, the others types of damages stay fixed at ten years. The most important revision is about the limit financial amount for the nuclear operator that is increased and the calculation of methods of funding for each contracting party is tackled. In fact it appears that more important funds will be available to make compensation for a more important number of victims. The revised system guarantees that the liability chain will never be broken. (N.C.)

  15. Caesium 137: Properties and biological effects resulting of an internal contamination;Cesium 137: proprietes et effets biologiques apres contamination interne

    Energy Technology Data Exchange (ETDEWEB)

    Lestaevel, P.; Racine, R.; Bensoussan, H.; Rouas, C.; Gueguen, Y.; Dublineau, I.; Bertho, J.M.; Gourmelon, P.; Jourdain, J.R.; Souidi, M. [Institut de Radioprotection et de Surete Nucleaire, IRSN, laboratoire de radiotoxicologie experimentale, direction de la radioprotection de l' homme, 92 - Fontenay-aux-Roses (France)

    2010-02-15

    Caesium-137 ({sup 137}Cs) is a radionuclide present in the environment mainly as the result of the atmospheric nuclear weapons testing and accidents arising in nuclear power plants like the Chernobyl accident in 1986. Nowadays, the health consequences resulting from a chronic exposure to this radionuclide remain unknown. After absorption, the caesium is distributed relatively homogeneously within the body, with a more important load in children than in adults. The toxicity of {sup 137}Cs is mainly due to its radiological properties. A high dose of {sup 137}Cs is responsible for a medullar dystrophy, disorders of the reproductive function, and effects on liver and renal functions. Disorders of bone mineralization and brain damages were also described in human beings. At lowest dose, {sup 137}Cs induces disturbances of wakefulness-sleep cycle, but not accompanied with behavioural disorders. The cardiovascular system was also perturbed. Biological effects of {sup 137}Cs on the metabolisms of the vitamin D, cholesterol and steroid hormones were described, but do not lead to clinical symptoms. In human beings, {sup 137}Cs leads to an immune deficiency, congenital and foetal deformations, an increased of thyroid cancer, as well as neurological disorders. It seems that children are more sensitive to the toxic effects of caesium than the adults. At present, the only effective treatment for the decorporation of the ingested {sup 137}Cs is the Prussian Blue (Radiogardase). The use of pectin to de-corporate the ingested {sup 137}Cs, in children notably, is sometimes proposed, but its administration still remains an open question. To conclude, the available scientific data suggest that {sup 137}Cs could affect a number of physiological and metabolic functions and consequently, could participate in the health risks associated to the presence of other contaminants in the environment. (authors)

  16. Geological, biological, and chemical data for Benthic Sediment Baseline Study of Mobile Bay from 3 Apr 1980 to 26 Aug 1981 (NODC Accession 0117430)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Abstract: Beginning in late 1979, the Alabama Coastal Area Board (CAB) funded a series of baseline surveys on the coastal resources of Alabama, from which they...

  17. French nuclear dissuasion after the cold war: continuity, ruptures, questions; La dissuasion nucleaire francaise apres la guerre froide: continuite, ruptures, interrogations

    Energy Technology Data Exchange (ETDEWEB)

    Tertrais, B

    2000-07-01

    Nuclear dissuasion is a slow and permanent process of adjustment to the strategic environment. French dissuasion adaptation to the new international environment covers a full decade, starting in the 1989-1992 era with a re-evaluation of defense programs. It has been followed by the 1994 defense white book which opens up the European perspective and reaches its peak in 1996 with a series of major decisions: renouncement of surface-to-surface missiles, launching of the M51 program, end of nuclear tests and shift towards simulation, dismantling of fissile materials production facilities etc. This process shows up two logics: the one of continuity with the confirmation of the bases of the French nuclear doctrine, and the one of discontinuity with significant changes in the general domain of the French nuclear policy. It also opens up questions about the field of application of dissuasion and the future of the nuclear consensus. (J.S.)

  18. After Chernobylsk, does an entitlement to environment mean?; Apres Tchernobyl, un droit a l'environnement a-t-il un sens?

    Energy Technology Data Exchange (ETDEWEB)

    Lemarchand, F. [UFR des Sciences Sociales de Caen, 14 (France)

    2008-07-15

    This article articulates in four points or perspectives: The first point is the question of the right of the peoples to have a livable world; The second point concerns the individual and collective responsibility in the consequences of our choices and our acts; The third point discusses the fact that the assurance does not cover any more an uncertain risk (cancers are predictable) but one time (when will appear these cancers). More, the radioinduced diseases are not repairable. The nuclear as the bio technologies are not insurable; The fourth point concerns the penal liability of the acts of the post accidental management, the nuclear lobby continues to preach the theory according to the fact that the Chernobylsk accident would not have almost any impact on health and on environment, considering that the closure of the nuclear power plant in 2000 has closed equally the file. Without epidemiological studies, made by national or international organizations, it stays difficult to devote the over mortality to Chernobylsk. (N.C.)

  19. About energy planning and wind energy after the Grenelle 2 Act; De la planification energetique et de l'energie eolienne apres la Loi Grenelle 2

    Energy Technology Data Exchange (ETDEWEB)

    Roche, C. [Faculte de Droit et des Sciences Sociales de Poitiers, 86 (France)

    2011-03-15

    With the Grenelle I and II Acts, the State has agreed to encourage the development of all renewable energy sources that can be economically viable, sustainable environmentally and to raise the share of sustainable energy to at least 23 % of final energy consumption by 2020, in accordance with its European commitments. Yet the Grenelle II Act, a 'legal monument', leaves one somewhat bemused on renewable energy matters. Far from simplifying applicable rules, it seems on the contrary to make procedures more complex by adding plans and guide-lines one on top of the other. Moreover, concerning 'facilities using the mechanical energy of wind', land sites seem to be paying the cost of stricter regulations with some facilities becoming Installations Classified for the Protection of the Environment (ICPE) and only the offshore wind energy industry seems to get real support by the Act. (author)

  20. Etude par microscopie electronique a balayage de l'endommagement par fatigue du cuivre apres implantation de divers elements (de He à Xe)

    Science.gov (United States)

    Mendez, J.; Violan, P.; Fayoux, C.

    1983-05-01

    The effect of ion implantation of the surface fatigue damage in polycrystalline copper has been studied. Several elements were employed, from He to Xe, which induce different defect structures. Implanted and non-implanted specimens were cycled up to rupture in tension-compression conditions under two cyclic stress levels. Fatigue tests were conducted at room temperature in laboratory air or in vacuum. Fatigue life is only modified on the He-implanted specimen cycled at the lower stress level; other implanted specimens do not show measurable changes in the fatigue lives. Scanning electron microscopy was used to characterize the effect of the implantations of the cyclic slip behaviour at the specimens surface. While Al or Cu implantations induce no changes and Xe implantation has a small effect, on the other hand, the implantation of He, B, C, N, O or Ar causes a strong inhibition of slip bands at the specimen surface. This inhibition is correlated with the nonsolubility of the elements in thermodynamic equilibrium conditions.

  1. Les mines de la péninsule Arabique d’après les auteurs arabes (VIIe - XIIe siècles

    Directory of Open Access Journals (Sweden)

    Audrey Peli

    2006-10-01

    Full Text Available A la période islamique, les principales ressources minières étaient situées en Iran oriental, en Afghanistan, en Espagne et au Maghreb. Cependant, la lecture des textes géographiques arabes et les recherches archéologiques prouvent que la péninsule Arabique n’en était pas dépourvue. Ainsi, le Hijâz, riche en gisements aurifères, a‑t‑il vraisemblablement contribué à la frappe de dînârs. En outre, le Yémen apparaît comme le plus diversement pourvu alors qu’en Oman était majoritairement exploité du cuivre. Par ailleurs, plusieurs étapes sur les principales routes sillonnant la péninsule ont été établies aux abords de sites miniers.During the Islamic period, the principal metal resources were situated in eastern Iran, in Afghanistan, in Spain and in the Maghreb. However, the Arabic geographical texts and the archaeological research show that the Arabian peninsula was also rich in mines. In this way, the rich gold‑mining Hijâz probably contributed to minting dînârs. Yemen was the richest region whereas, Oman exploited principally copper. Furthermore, a number of mining sites are known by the texts as stations on the principal roads of the Arabian peninsula.

  2. La place des chrétiens dans la Cordoue des Omeyyades, d’après leurs églises (VIIIe-Xe siècles

    Directory of Open Access Journals (Sweden)

    Molénat, Jean Pierre

    2012-06-01

    Full Text Available This article begins examining closely all written testimonies that allow to situate churches in Cordova and its surroundings during the eighth-tenth centuries, and concludes that if there were Christian worship places in the countryside and the mountains (the monasteries of the sierra, and the city suburbs (arrabales/arbād, none may be localised with certainty in the madīna, the old walled city. The second part is an attempt to explain such situation, with the help of legal texts of the time, particularly of a fatwā that took place at the beginning of the tenth century, claiming that church building or restoration was allowed only apart from the view of Muslims, and off their “sanctuary” (haram. The conclusion is that, if there were churches indeed, and Christians attending them, in Cordova, during the eighth to tenth centuries, they where located in the urban periphery, and their integration in the city resulted only from the growth of the agglomeration and the mass conversion movement, at the end of the eighth and during the tenth century, re-introducing the religious mix that Muslim authorities had tried to prevent.[fr] Cet article commence par examiner tous les témoignages textuels permettant de situer des églises dans la Cordoue des VIIIe-Xe siècles et ses environs. La conclusion est que si l’on rencontre bien des lieux de culte chrétiens dans la campagne et dans la montagne (notamment les monastères de la sierra, ainsi que dans les « faubourgs » (arrabales de la ville, il est impossible d’en situer avec certitude à l’intérieur de la madīna, la vieille ville entourée de murailles. La seconde partie du travail cherche à expliquer cette situation par l’examen des textes juridiques de l’époque, et notamment une fatwā de début du Xe siècle, qui déclare qu’on ne peut construire, ou restaurer, des églises, qu’hors de la vue des musulmans, et à l’écart de leur « sanctuaire » (haram. La conclusion est que s’il y avait bien des églises, et des chrétiens pour les fréquenter, dans la Cordoue des VIIIe-Xe siècles, elles étaient situées dans la périphérie urbaine, leur intégration dans la ville résultant seulement de la croissance de l’agglomération à la fin du IXe et au Xe siècle, en même temps que du mouvement de conversion massive, qui ont réintroduit une mixité religieuse que les autorités islamiques prétendaient éviter.

  3. Finite element analysis in fluids; Proceedings of the Seventh International Conference on Finite Element Methods in Flow Problems, University of Alabama, Huntsville, Apr. 3-7, 1989

    Science.gov (United States)

    Chung, T. J.; Karr, Gerald R.

    Recent advances in computational fluid dynamics are examined in reviews and reports, with an emphasis on finite-element methods. Sections are devoted to adaptive meshes, atmospheric dynamics, combustion, compressible flows, control-volume finite elements, crystal growth, domain decomposition, EM-field problems, FDM/FEM, and fluid-structure interactions. Consideration is given to free-boundary problems with heat transfer, free surface flow, geophysical flow problems, heat and mass transfer, high-speed flow, incompressible flow, inverse design methods, MHD problems, the mathematics of finite elements, and mesh generation. Also discussed are mixed finite elements, multigrid methods, non-Newtonian fluids, numerical dissipation, parallel vector processing, reservoir simulation, seepage, shallow-water problems, spectral methods, supercomputer architectures, three-dimensional problems, and turbulent flows.

  4. The Party's Over: Oil, War And The Fate Of Industrial Societies; Petrole la fete est finie. Avenir des societes industrielles apres le pic petrolier

    Energy Technology Data Exchange (ETDEWEB)

    Heinberg, R

    2008-07-01

    The world is about to run out of cheap oil and change dramatically. Within the next few years, global production will peak. Thereafter, even if industrial societies begin to switch to alternative energy sources, they will have less net energy each year to do all the work essential to the survival of complex societies. We are entering a new era, as different from the industrial era as the latter was from medieval times. In 'The Party's Over', Richard Heinberg places this momentous transition in historical context, showing how industrialism arose from the harnessing of fossil fuels, how competition to control access to oil shaped the geopolitics of the twentieth century and how contention for dwindling energy resources in the twenty-first century will lead to resource wars in the Middle East, Central Asia and South America. He describes the likely impacts of oil depletion and all of the energy alternatives. Predicting chaos unless the United States-the world's foremost oil consumer-is willing to join with other countries to implement a global program of resource conservation and sharing, he also recommends a 'managed collapse' that might make way for a slower-paced, low-energy, sustainable society in the future. More readable than other accounts of this issue, with fuller discussion of the context, social implications and recommendations for personal, community, national and global action, Heinberg's updated book is a riveting wake-up call for human-kind as the oil era winds down, and a critical tool for understanding and influencing current US foreign policy.

  5. Metallurgical coatings and thin films; Proceedings of the International Conference, 18th, San Diego, CA, Apr. 22-26, 1991. Vols. 1 & 2

    Science.gov (United States)

    Mcguire, Gary E. (Editor); Mcintyre, Dale C. (Editor); Hofmann, Siegfried (Editor)

    1991-01-01

    A conference on metallurgical coatings and thin films produced papers in the areas of coatings for use at high temperatures; hard coatings and deposition technologies; diamonds and related materials; tribological coatings/surface modifications; thin films for microelectronics and high temperature superconductors; optical coatings, film characterization, magneto-optics, and guided waves; and methods for characterizing films and modified surfaces.

  6. Relativit\\'e g\\'en\\'erale (d'apr\\`es M.Vaugon) et quelques probl\\`emes math\\'ematiques qui en sont issus

    CERN Document Server

    Humbert, Emmanuel

    2010-01-01

    This text aims to explain general relativity to geometers who have no knowledge about physics. Using handwritten notes by Michel Vaugon, we first construct the bases of the theory. Then, we describe the physical context of some mathematical problems coming from general relativity. ----- Ce texte s'adresse aux g\\'eom\\`etres, qui veulent comprendre la relativit\\'e g\\'en\\'erale mais qui n'ont aucune connaissance en physique. Nous expliquons d'abord les bases de la th\\'eorie en nous appuyant sur des notes manuscrites de Michel Vaugon et nous abordons ensuite quelques probl\\`emes math\\'ematiques issus de la relativit\\'e et que nous repla\\c{c}ons dans un contexte physique.

  7. Post-radiation mucocele in two patients treated for nasopharyngeal cancer; Mucocele apres radiotherapie chez deux patients traites pour cancer du nasopharynx

    Energy Technology Data Exchange (ETDEWEB)

    Mnejja, M.; Hammami, B.; Achour, I.; Chakroun, A.; Charfeddine, I.; Ghorbel, A. [Service ORL et chirurgie cervico-faciale, CHU Habib-Bourguiba, 3029 Sfax (Tunisia); Frikha, M. [Service de carcinologie, CHU Habib-Bourguiba, 3029 Sfax (Tunisia); Daoud, J. [Service de radiotherapie, CHU Habib-Bourguiba, 3029 Sfax (Tunisia)

    2011-06-15

    A 30-year-old woman, with a history of nasopharyngeal carcinoma, which was treated by radiotherapy nine years previously, presented with occasional diplopia and recent headaches. A nasopharyngeal biopsy showed no recurrence. The imaging revealed a sphenoidal sinus mucocele. Endoscopic marsupialization of the mucocele allowed clinical improvement. A 56-year-old woman presented, five years after radiotherapy for nasopharyngeal carcinoma, with a fronto-orbital mass. CT-scan revealed a fronto-ethmoidal mucocele. Nasopharyngeal biopsy showed tumour recurrence. Marsupialization of mucocele was performed. Recurrence of the carcinoma was treated by radiotherapy and chemotherapy. Sphenoidal sinus mucocele developing after radiotherapy for nasopharyngeal carcinoma has rarely been reported. CT scan and MRI are useful tools in making the diagnosis. Biopsy is required to diagnose recurrence or associated radio-induced tumor. Endoscopic approach gives good results. (authors)

  8. Analysis of the behaviour of embankment dams during and after impoundment; Analyse du comportement de barrages en remblai pendant et apres leur mise en eau

    Energy Technology Data Exchange (ETDEWEB)

    Massiera, M. [Moncton Univ., Moncton, NB (Canada). Dept. of Civil Engineering; Szostak-Chrzanowski, A; Bazanowski, M. [New Brunswick Univ., Fredericton, NB (Canada). Canadian Centre for Geodetic Engineering; Withaker, C. [Metropolitan Water District of Southern California MWD, Glendora, CA (United States)

    2009-07-01

    This paper analyzed the behaviour of 2 embankment dams during impoundment. The study compared the values of the observed and calculated displacements of the crest during the initial filling of the reservoirs at the zoned earth West Dam in California and the Tounustouc concrete face rockfill dam (CFRD) in Quebec. The calculations were performed using finite element analysis. Rock and earthfill dams constructed on moraine deposits are known to deform under the influence of water load as the reservoir is filled. Therefore, this study also analyzed the long term deformations of the West Dam during 4 subsequent years of operation of the reservoir. Modelling rock and earthfill dams takes into account the nonlinear behaviour of the construction materials; interaction between the structure and the underlying soil and rock strata; influence of water load on the structure and on the foundation bedrock; and the effects of water saturation. This paper showed that geotechnical and geodetic monitoring may provide a warning system in case of abnormal behaviour of the embankment dam. In tectonically active zones, monitoring surveys may also provide information on the effects of seismic disturbances. 18 refs., 11 figs.

  9. Étude des anomalies chromosomiques après radiothérapie chez des patients traités pour lymphome malin non-Hodgkinien

    Science.gov (United States)

    Mahe, M. A.; André, M. J.; Moyon, E.; Le Mevel, A.; Soubeyran, P.; Hamidou, M.; Milpied, N.; Bourdin, S.; Cuillière, J. C.; Chatal, J. F.

    1998-04-01

    Structural chromosome defects were evaluated in the lymphocytes of 30 patients (pts) who had undergone radiotherapy for non Hodgkin's lymphoma (NHL). Twelve had received 20 Grays (Gy) over the abdomen (group I), 12 whole body irradiation at 1.5 Gy (group II) and 6 whole body irradiation at 15 Gy (group III). A cohort of 468 unirradiated pts served as controls. For the irradiated group, 7% of cells had aberrations compared to 0.4% in controls {P statistically higher in group I (12%) than in group II (3.5%) and III (2.5%) . In group I, frequency of aberrations was statistically higher in pts who had additionnal extra-abdominal involved field irradiation, those with evolutive NHL and those receiving chemotherapy at the time of the cytogenetic analysis. Les aberrations chromosomiques ont ,été, mesurées sur les lymphocytes de 30 patients (pts) irradiés pour lymphome malin non-hodgkinien (LNH) selon 3 modalités : 20 Grays (Gy) sur l'abdomen (groupe I : 12 pts), Irradiation corporelle totale 1,5 Gy (groupe II : 12 pts), ou 15 Gy (groupe III : 6 pts). Une population non irradiée de 468 pts a servi de témoin. Dans le groupe irradié, 7 % des cellules présentaient des anomalies contre 0,4 % dans le groupe témoin {P <10-6}. Les aberrations ,étaient statistiquement plus nombreuses dans le groupe I (12 % des cellules) que dans les groupes II (3,5 %) et III (2,5 %). Dans le groupe I, les anomalies , étaient statistiquement plus fréquentes chez les pts ayant eu une irradiation localisée extra-abdominale en complément de celle de l'abdomen ainsi que chez ceux en rechute de leur LNH et ceux recevant une chimiothérapie lors de l',étude cytogénétique.

  10. Applications of artificial intelligence 1993: Knowledge-based systems in aerospace and industry; Proceedings of the Meeting, Orlando, FL, Apr. 13-15, 1993

    Science.gov (United States)

    Fayyad, Usama M. (Editor); Uthurusamy, Ramasamy (Editor)

    1993-01-01

    The present volume on applications of artificial intelligence with regard to knowledge-based systems in aerospace and industry discusses machine learning and clustering, expert systems and optimization techniques, monitoring and diagnosis, and automated design and expert systems. Attention is given to the integration of AI reasoning systems and hardware description languages, care-based reasoning, knowledge, retrieval, and training systems, and scheduling and planning. Topics addressed include the preprocessing of remotely sensed data for efficient analysis and classification, autonomous agents as air combat simulation adversaries, intelligent data presentation for real-time spacecraft monitoring, and an integrated reasoner for diagnosis in satellite control. Also discussed are a knowledge-based system for the design of heat exchangers, reuse of design information for model-based diagnosis, automatic compilation of expert systems, and a case-based approach to handling aircraft malfunctions.

  11. Après Einstein. Después de Einstein: la teoría de la relatividad y su difusión para la arquitectura

    OpenAIRE

    Gutiérrez Calderón, Pablo Jesús

    2012-01-01

    Influencia de la teoría de la relatividad en la teoría arquitectónica atendiendo a la ruptura de los conceptos newtonianos de espacio y tiempo, la identificación de materia y energía y aplicación de campos cuatridimensionales en arquitectura.

  12. Comparison of THALES and VIPRE-01 Subchannel Codes for Loss of Flow and Single Reactor Coolant Pump Rotor Seizure Accidents using Lumped Channel APR1400 Geometry

    International Nuclear Information System (INIS)

    Subchannel analysis plays important role to evaluate safety critical parameters like minimum departure from nucleate boiling ratio (MDNBR), peak clad temperature and fuel centerline temperature. In this study, two different subchannel codes, VIPRE-01 (Versatile Internals and Component Program for Reactors: EPRI) and THALES (Thermal Hydraulic AnaLyzer for Enhanced Simulation of core) are examined. In this study, two different transient cases for which MDNBR result play important role are selected to conduct analysis with THALES and VIPRE-01 subchannel codes. In order to get comparable results same core geometry, fuel parameters, correlations and models are selected for each code. MDNBR results from simulations by both code are agree with each other with negligible difference. Whereas, simulations conducted by enabling conduction model in VIPRE-01 shows significant difference from the results of THALES

  13. Symposium on Recent Developments in Large-Scale Computational Fluid Dynamics, University of Minnesota, Minneapolis, Apr. 23, 24, 1990, Technical Papers

    Science.gov (United States)

    Tezduyar, Tayfun E.; Hughes, Thomas J. R.

    1991-06-01

    Methodologies and applications in finite difference, finite element, and finite volume techniques, and spectral methods are considered. Topics discussed include a dual-porosity model for waterflooding in naturally fractured reservoirs, Navier-Stokes simulations of flow past 3D submarine models, current CFD issues relevant to the incompressible Navier-Stokes equations, efficient direct solvers for large-scale CFD problems, adaptive streamline diffusion methods for compressible flow using conservation variables, computational methods for shock waves in a 3D supersonic flow, the computation of 3D flows using unstructured grids, a large-scale method of lines solution of fluid dynamics equations on Japanese supercomputers, and time-accurate incompressible flow computations with quadrilateral velocity-pressure elements.

  14. Politique et stratégie énergétiques de l’Inde avant et après Copenhague 2009

    Directory of Open Access Journals (Sweden)

    Megha Shenoy

    2011-05-01

    Full Text Available L’Inde est un pays démocratique d’une extraordinaire diversité. Sa croissance économique est l’une des plus rapides au monde. C’est le sixième plus grand consommateur mondial d’énergie. Ses politiques et ses stratégies énergétiques suscitent un intérêt de plus en plus important en raison de leur impact considérable sur les relations géopolitiques, sur les prix mondiaux de l’énergie et sur les changements climatiques. Actuellement, sa consommation d’énergie per capita et ses valeurs d’émissions de gaz à effet de serre sont faibles. Cependant, elles sont vouées à augmenter si le pays emprunte la même trajectoire de développement que l’Occident. Pour que l’Inde saute par-dessus ces sentiers déjà souvent battus pour en atteindre un qui garantisse un développement durable, le pays doit impérativement redéfinir son paradigme de développement de sorte à assurer une croissance inclusive. Des subventions inviables, une mise en œuvre des réformes laissant à désirer, des prix énergétiques faussés et des investissements inadaptés dans des énergies renouvelables sont quelques-unes des principales entraves que le gouvernement indien doit réexaminer afin d’améliorer la sécurité énergétique et de fournir un cadre de transition vers une économie à faible intensité de carbone. Outre des politiques énergétiques innovatrices telles que la Mission solaire nationale (National Solar Mission, la Mission nationale pour l’amélioration de l’efficacité énergétique (National Mission on Enhanced Energy Efficiency et la Mission nationale pour l’habitat durable (National Mission on Sustainable Habitat, l’Inde a besoin d’adopter un cadre de croissance découplée, que nous considérons comme une amélioration de la qualité de vie des citoyens sans pour autant intensifier les dommages à l’environnement. Depuis 2008, l’Inde démontre qu’elle prend au sérieux le changement de son modèle de croissance et le passage à des énergies propres. Néanmoins, ces perspectives ne se réaliseront pas pleinement si l’hémisphère Nord n’apporte pas une aide technique et financière pour atténuer collectivement les effets nuisibles du réchauffement de la planète et des changements climatiques qu’il provoque.

  15. Analyse de la repartition géographique des Malphigiaceae d’apres les caractêres du pollen et de la pollinisation

    Directory of Open Access Journals (Sweden)

    D. Lobreau-Callen

    1983-12-01

    Full Text Available ANALYSIS OF THE GEOGRAPHICAL DISTRIBUTION OF MALPHIGIACEAE USING POLLEN ANDPOLLINATION CHARACTERS A comparative study o f pollen and pollination in the family Malphigiaceae shows that the genera o f the Old World are derived from those in South America. They have existed on the continents involved since the Cretaceous. In South America there is coadaptation oetween the pollen characters and the pollinating insects present only on this continent and subsequently diversified after the enlargement o f the Atlantic in the Tertiary. Pollen characters o f the Malphigiaceae show affinities with those o f other families o f the Polygalales. Palynologically, Malphigiaceae approaches Euphorbiaceae on the one hand, and Leguminosae and Rutales-Sapindales on the other.

  16. Radio Milano Libertà entre URSS et Italie, du début des années 1940 à l’après-guerre

    OpenAIRE

    Romitelli, Valerio

    2013-01-01

    Au début de l’été 1941 à Moscou, Togliatti est chargé de diriger de nouvelles radios qui sont créées et installées au siège du Kominterm. Le but est de diffuser les orientations du communisme mondial dans plusieurs pays occupés par les nazis et les fascistes. La singularité des émissions de Radio Milano Libertà et de la Voce della Verità, c’est qu’elles feignent d’émettre directement depuis l’Italie : le but étant de faire croire à l’existence dans ce pays à un dissentiment bien organisé cont...

  17. La métaplasie osteoide de l'endomètre après une grossesse à terme: à propos d'un cas rare

    Science.gov (United States)

    Jayi, Sofia; Bouguern, Hakima; Fatemi, Hind; Chaara, Hikmat; Laamarti, Afaf; Melhouf, Aabdelilah

    2013-01-01

    La métaplasie ostéoïde de l'endomètre (MOE) est une entité rare correspondant à la présence de tissu osseux dans l'endomètre, elle est le plus souvent diagnostiquée dans un contexte d'infertilité secondaire faisant suite à une grossesse interrompue. Même si plusieurs facteurs de risque sont répertoriés, sa physiopathologie reste mal connue et sa traduction clinique est très variable. Nous rapportons un cas de MOE apparu suite à un curetage pour rétention placentaire en post-partum. Le diagnostic a été suspecté par l'hystéroscopie et confirmé par l’étude anatomopathologique. A notre connaissance c'est le premier cas décrit suite à un accouchement à terme. A travers notre cas et à la lumière d'une revue de la littérature nous insistons sur les caractéristiques épidémiologiques, physiopathologiques, cliniques et para cliniques de cette entité rare, dont la connaissance est primordiale pour un diagnostic sûr et par conséquent un traitement adapté permettant souvent de récupérer la fertilité de la patiente. PMID:23898363

  18. La métaplasie osteoide de l'endomètre après une grossesse à terme: à propos d'un cas rare

    OpenAIRE

    Jayi, Sofia; Bouguern, Hakima; Fatemi, Hind; Chaara, Hikmat; Laamarti, Afaf; Melhouf, Aabdelilah

    2013-01-01

    La métaplasie ostéoïde de l'endomètre (MOE) est une entité rare correspondant à la présence de tissu osseux dans l'endomètre, elle est le plus souvent diagnostiquée dans un contexte d'infertilité secondaire faisant suite à une grossesse interrompue. Même si plusieurs facteurs de risque sont répertoriés, sa physiopathologie reste mal connue et sa traduction clinique est très variable. Nous rapportons un cas de MOE apparu suite à un curetage pour rétention placentaire en post-partum. Le diagnos...

  19. Coadministration of Hedera helix L. Extract Enabled Mice to Overcome Insufficient Protection against Influenza A/PR/8 Virus Infection under Suboptimal Treatment with Oseltamivir

    OpenAIRE

    Eun-Hye Hong; Jae-Hyoung Song; Aeri Shim; Bo-Ra Lee; Bo-Eun Kwon; Hyuk-Hwan Song; Yeon-Jeong Kim; Sun-Young Chang; Hyeon Gun Jeong; Jong Geal Kim; Sang-Uk Seo; HyunPyo Kim; YongSoo Kwon; Hyun-Jeong Ko

    2015-01-01

    Several anti-influenza drugs that reduce disease manifestation exist, and although these drugs provide clinical benefits in infected patients, their efficacy is limited by the emergence of drug-resistant influenza viruses. In the current study, we assessed the therapeutic strategy of enhancing the antiviral efficacy of an existing neuraminidase inhibitor, oseltamivir, by coadministering with the leaf extract from Hedera helix L, commonly known as ivy. Ivy extract has anti-inflammatory, antiba...

  20. A methodology for airplane parameter estimation and confidence interval determination in nonlinear estimation problems. Ph.D. Thesis - George Washington Univ., Apr. 1985

    Science.gov (United States)

    Murphy, P. C.

    1986-01-01

    An algorithm for maximum likelihood (ML) estimation is developed with an efficient method for approximating the sensitivities. The ML algorithm relies on a new optimization method referred to as a modified Newton-Raphson with estimated sensitivities (MNRES). MNRES determines sensitivities by using slope information from local surface approximations of each output variable in parameter space. With the fitted surface, sensitivity information can be updated at each iteration with less computational effort than that required by either a finite-difference method or integration of the analytically determined sensitivity equations. MNRES eliminates the need to derive sensitivity equations for each new model, and thus provides flexibility to use model equations in any convenient format. A random search technique for determining the confidence limits of ML parameter estimates is applied to nonlinear estimation problems for airplanes. The confidence intervals obtained by the search are compared with Cramer-Rao (CR) bounds at the same confidence level. The degree of nonlinearity in the estimation problem is an important factor in the relationship between CR bounds and the error bounds determined by the search technique. Beale's measure of nonlinearity is developed in this study for airplane identification problems; it is used to empirically correct confidence levels and to predict the degree of agreement between CR bounds and search estimates.

  1. What about sexual life after therapy for prostate cancer?; Y a t-il une vie sexuelle apres traitement d'un cancer prostatique?

    Energy Technology Data Exchange (ETDEWEB)

    Cosset, J.M. [Institut Curie, 75 - Paris (France)

    2002-05-01

    The precise assessment of sexual dysfunction after treatment of prostatic cancer cannot be avoided in 2002. These iatrogenic complications may significantly alter the quality of life of the patients. In addition, sexual toxicity is progressively becoming a cardinal parameter for the treatment choice, both for the patient and the physician. Significant efforts allowed to reduce sexual toxicity after therapy in the recent years. As an example, nerve-sparing surgical techniques have been proposed, whenever reasonable. However, in spite of these surgical advances, data suggest that overall, the new irradiation techniques (conformal radiotherapy and brachytherapy) are responsible for less alteration of sexual life than surgery. Another potential advantage is that sildenafil (Viagra) is able to restore potency in a majority of cases after radiotherapy, while it is usually poorly effective after surgery. (author)

  2. Facilities license application record data as of April 1, 1981. Tri-annual report 30 Nov 80-1 Apr 81

    International Nuclear Information System (INIS)

    The FLAR is divided into three parts as follows: Part I - The first part is a listing of all operating licenses, authorizations and construction permits in effect plus applications pending; Part II - The second part is a listing of applications that have been withdrawn or denied, and licenses and construction permits terminated or revoked; and Part III - The third part is a listing of research, test and power reactors for export

  3. La géopolitique interne de l’Equateur après la « révolution citoyenne »

    Directory of Open Access Journals (Sweden)

    Alexis Sierra

    2010-02-01

    Full Text Available En 2009, les élections générales en Equateur ont clôturé la première étape de rénovation politique initiée par le président Rafael Correa. Leur analyse montre l'existence de nouveaux équilibres politiques régionaux alors que le pays doit faire face à de nouveaux défis économiques et sociaux.The general elections in Ecuador in 2009 closed the first stage of political renovation started by president Rafael Correa. Their analysis show the existence of new political balance between regions while the country have to take up new social and economical challenge.

  4. Etude comparative sur la propagation de l'endommagement apres impact des composites carbone/epoxy renforces par piquage au fil Kevlar et titane-nickel

    Science.gov (United States)

    Vachon, Pierre-Luc

    Composite laminates have strong in-plane mechanical properties, but they are generally weaker through their thickness. This specificity makes the laminates prone to delamination, particularly under low-velocity impact loads. Consequently numerous research efforts have been dedicated to developing interlaminar reinforcing methods, such as transverse stitching. The present project proposes the use of the stitching technique combined with a special stitching thread made of superelastic TiNi alloy. This technology is intended to improve the delamination toughness in composite laminates loaded in bending. In the first part of this study a numerical model was developed for analyzing composite structures. The 3-D finite element model was built with the ANSYS commercial software using 20-node solid and 8-node shell elements. The progressive damage modeling technique was used, allowing the prediction of delamination propagation in a laminate submitted to various loading modes. The model was validated for a plate under quasi-static traction load, and it was then used to simulate three-point bending tests. Secondly, carbon/epoxy composite panels were fabricated, with each panel containing unstitched and stitched specimens. Two different materials were used for the stitching thread: superelastic TiNi wires and Kevlar threads as a reference. Some stitched specimens were cut in slices in order to make some observations of the internal stitch using an optical microscope. Standardized low-velocity impact tests and compression after impact tests were carried out on stitched and unstitched specimens (ASTM D7136 and D7137). The Kevlar reinforcements have shown great performance in reducing the delaminated zone after impact, as well as in improving the residual compression strength. The TiNi reinforcements provided encouraging results during the impact tests, though being less effective than the Kevlar threads. During the compression after impact tests, only a slight difference could be measured between the TiNi-stitched and the unstitched specimens. Then the bending performance of the specimens was quantified experimentally by calculating the energy required to create a unit volume of damaged material (Gv, J/mm3). This metric is similar to the Strain Energy Release Rate (SERR) commonly used in studies on delamination. According to the experimental results, the damage resistance in three-point bending was not improved by the Kevlar reinforcements, despite the reduced damaged zone after the impact test. Indeed, when the strain energy in bending is relativized to the induced damaged volume during propagation, it turns out that the TiNi reinforcements are more effective than the Kevlar's for improving the damage resistance. Finally, the numerical study on the behavior of both types of stitched reinforcements allowed identifying subtle differences between those. Indeed, both stitching threads (TiNi and Kevlar) promoted the interlaminar propagation of the delamination during simulation of the bending test, with this behavior being less pronounced for the TiNi-stitched plate. However the Kevlar threads seemed more effective for stopping this propagation in the zones between the stitches. Keywords: composite materials, stitching, numerical model, shape memory alloy, three-point bending, low-velocity impact, ultrasound imaging.

  5. Comparison of THALES and VIPRE-01 Subchannel Codes for Loss of Flow and Single Reactor Coolant Pump Rotor Seizure Accidents using Lumped Channel APR1400 Geometry

    Energy Technology Data Exchange (ETDEWEB)

    Oezdemir, Erdal; Moon, Kang Hoon; Oh, Seung Jong [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of); Kim, Yongdeog [KHNP-CRI, Daejeon (Korea, Republic of)

    2014-10-15

    Subchannel analysis plays important role to evaluate safety critical parameters like minimum departure from nucleate boiling ratio (MDNBR), peak clad temperature and fuel centerline temperature. In this study, two different subchannel codes, VIPRE-01 (Versatile Internals and Component Program for Reactors: EPRI) and THALES (Thermal Hydraulic AnaLyzer for Enhanced Simulation of core) are examined. In this study, two different transient cases for which MDNBR result play important role are selected to conduct analysis with THALES and VIPRE-01 subchannel codes. In order to get comparable results same core geometry, fuel parameters, correlations and models are selected for each code. MDNBR results from simulations by both code are agree with each other with negligible difference. Whereas, simulations conducted by enabling conduction model in VIPRE-01 shows significant difference from the results of THALES.

  6. Nation, religion et genre: se forger une nouvelle identité après la guerre en Bosnie-Herzégovine

    OpenAIRE

    Bretonnière, Sandrine

    2010-01-01

    In the context of post-war Bosnia, this article analyzes the processes by which Bosnian muslim women restructure their identities, combining different elements such as gender, religion and citizenship. Distancing themselves from prescribed social roles inherited from the Yugoslav era, they strive to forge individual subjectivities. This requires the recognition of a Bosnian national identity, which grounds their legitimity as citizens in public space. Our study then shows the different arrang...

  7. Treatment modalities of oral mucositis after radiation of head and neck cancers; Prise en charge des mucites apres radiotherapie des cancers des voies aerodigestives superieures

    Energy Technology Data Exchange (ETDEWEB)

    Lapeyre, M.; Charra-Brunaud, C.; Kaminsky, M.C.; Geoffrois, L.; Dolivet, G.; Pourel, N.; Marchal, C.; Bey, P.; Maire, F.; Simon, M. [Centre Alexis-Vautrin, 54 - Vandoeuvre-les-Nancy (France); Toussaint, B. [Hopital Central, Service de Chirurgie ORL, 54 - Nancy (France)

    2001-11-01

    Acute mucositis is common after radiotherapy for head and neck cancers. During the past 3 decades, there was a gradual evolution in the treatment modalities for locally advanced carcinomas (concomitant radio-chemotherapy, accelerated radiotherapy). These new strategies are accompanied by an increase in early mucosal reactions. At the present time, there is no widely accepted prophylaxis or effective treatment. Many traditional remedies or new agents seem ineffective (Sucralfate, Chlorhexidine, GM-CSF, Silver nitrate, Prostaglandin, anti-oxidants, Benzydamine hydrochloride), while others seem promising (Povidone-iodine, nonabsorbable antibiotic lozenges and anti-fungal, local GM-CSF, Glutamide, Low-energy laser, corticosteroids). Radioprotectors are controversial and should be only used in experimental protocols and not in routine practice. However, some recommendations can be proposed: general prevention and global care before cancer therapy should be systematic (oral hygiene, dental and periodontal treatment, advice to avoid the use of tobacco and alcohol); frequent oral rinsing with a bland mouthwash (Povidone-iodine or others) should be used at the start of treatment because there are significant modifications of the oral microflora increased by a disturbed salivary flow; these mouthwashes could be associated with nonabsorbable antibiotic lozenges or anti-fungal topical (bicarbonates, Amphotericine B); Systematic percutaneous fluoroscopic gastrostomy should be decided before any aggressive treatments (concomitant radio-chemotherapy, accelerated radiotherapy); pain should be controlled; finally, the radiation technique should be optimized (mucosal sparing block, conformal radiotherapy and intensity modulated radiation therapy). (authors)

  8. Mud and stud refurbishing workshop coordinated and run jointly with East Midlands Earth Structure Society [organisation, facilitation, research] Tumby, Lincolnshire, UK; 28 Apr 2012

    OpenAIRE

    Kolakowski, Marcin M.

    2012-01-01

    Students Workshop for ArchiLOVE - Students Research Group - coordinated by MM Kolakowski and EMESS (East Midlands Earth Structure Society: preparing wood and earth-straw mix for Mud and Stud construction, lime wash, constructing Lincolnshire Mud and Stud walls.

  9. Première expérience de l'utilisation du Misoprostol comme soin après avortement (SAA) à Libreville, Gabon

    OpenAIRE

    Mayi-Tsonga, Sosthène; Minkobame, Ulysse; Mbila, Arielle; Assoumou, Pamphile; Diop, Ayisha; Winikoff, Beverly

    2014-01-01

    Introduction Une étude a été menée afin de déterminer le taux d'acceptabilité de 400µg de misoprostol par voie sublinguale comme traitement de première intention de l'avortement incomplet et de préciser le taux d'avortement complet ou vacuité utérine. Méthodes Les femmes éligibles avaient un diagnostic clinique d'avortement incomplet avec une taille utérine inférieure à celle d'un utérus de 12 semaines d'aménorrhées (SA). Chacune a reçu 400µg de misoprostol par voie sublinguale. Les femmes on...

  10. Hilda Mundy : guerre, après-guerre et modernité : écriture d’avant-garde dans la Bolivie des années 30

    OpenAIRE

    Zavala Virreira, Rocio

    2013-01-01

    A Bolivian writer in the thirty's - forgotten until the 90's - Hilda Mundy became known especially at the end of the Chaco War (1932-1935) and in the immediate post-War period as a humouristic columnist in Oruro, the town where she was born. All her columns are instances of a literature of manners, on which she turns a critical and satirical eye. Her remarks on hypocritical and sanctimonious moral standards of her time are particularly scathing. Hilda Mundy's texts satirize the powerful and t...

  11. Apres les élections américaines, l’avenir incertain des projets de loi énergie-climat au Sénat

    OpenAIRE

    Méritet, Sophie

    2010-01-01

    The climate – energy project bill, voted in the House of Representatives in 2009, has undergone many changes since it is studied by the Senate. Discussions have been slowed by health reform in 2010 and then by the oil spill in the Gulf of Mexico. The midterm elections are perceived as a new obstacle in the further discussions and a possible vote on a bill in the coming months. Opponents highlight the economic constraints of such law while the United States is experiencing the most severe econ...

  12. Agnès Sinaï (dir.), Économie de l’après-croissance. Politiques de l’Anthropocène II

    OpenAIRE

    Chabert, Thomas

    2015-01-01

    Cet ouvrage constitue le deuxième volet de la série Politiques de l’Anthropocène, publiée sous la direction d’Agnès Sinaï. Les dix contributeurs étudient les théories économiques qui ont alimenté l’idée d’une croissance économique indéfinie ainsi que les nouvelles « utopies » que sont censées représenter la croissance verte ou l’économie circulaire. Tous nous mettent en garde face aux « mirages » de la théorie économique dominante et nous invitent à explorer les pistes d’une économie biophysi...

  13. Probing Dynamics of Electron Acceleration with Radio and X-ray Spectroscopy, Imaging, and Timing in the 2002 Apr 11 Solar Flare

    CERN Document Server

    Fleishman, Gregory D; Nita, Gelu M; Gary, Dale E

    2013-01-01

    Based on detailed analysis of radio and X-ray observations of a flare on 2002 April 11 augmented by realistic 3D modeling, we have identified a radio emission component produced directly at the flare acceleration region. This acceleration region radio component has distinctly different (i) spectrum, (ii) light curves, (iii) spatial location, and, thus, (iv) physical parameters from those of the separately identified, trapped or precipitating electron components. To derive evolution of physical parameters of the radio sources we apply forward fitting of the radio spectrum time sequence with the gyrosynchrotron source function with 5 to 6 free parameters. At the stage when the contribution from the acceleration region dominates the radio spectrum, the X-ray- and radio- derived electron energy spectral indices agree well with each other. During this time the maximum energy of the accelerated electron spectrum displays a monotonic increase with time from ~ 300 keV to ~ 2 MeV over roughly one minute duration indic...

  14. Terre-Neuve ou la carte éclatée d'après le «Grand Insulaire» d'André Thevet

    Directory of Open Access Journals (Sweden)

    Frank LESTRINGANT

    1987-09-01

    Full Text Available Les deux cartes relatives à Terre-Neuve, représentée comme un archipel, que l'on trouve dans le Grand Insulaire inachevé du cosmographe André Thevet (circa, 1586, sont un bon témoignage des errements en partie calculés auxquels se prêtait la cartographie à l'époque des Grandes Découvertes. Pour vaincre des contraintes techniques d'une part, telles que la nécessité du montage entre des données disparates, et pour affirmer d'autre part le dessein d'une entreprise de conquête, le cosmographe — ou géographe universel — est amené à truquer, selon les règles de l'art, un document composite, prélevé à l'origine sur le planisphère de Mercator et augmenté d'informations venues des routiers portulans. Une île inédite, qui porte le nom de Thevet, a pour fonction de signer le tout.

  15. Thermosense XII; Proceedings of the International Conference on Thermal Sensing and Imaging Diagnostic Applications, Orlando, FL, Apr. 18-20, 1990

    Science.gov (United States)

    Semanovich, Sharon A.

    Various papers on thermal sensing and imaging diagnostic applications are presented. Individual topics addressed include: material property measurements with postprocessed thermal image data, recent advances in digital thermography for NDE, numerical modeling of thermographic NDT for graphite epoxy laminates, transient thermographic NDE of turbine blades, fault location in printed wiring boards using thermal imaging, dynamic thermal tomography, influence of temperature gradients on the measurement accuracy of IR imaging systems. Also discussed are: Spacelab-qualified IR imager for microgravity science applications, theoretical and experimental analysis of the modulation response of a sample IR imaging system, IR-visualized air turbulence, noise and artifact reduction in IR thermography, noise suppression in IR thermal-wave video images by real-time processing in synchronism with active stimulation of the target, hydrogen fire-detection using thermal imaging and its application to space launch vehicles, automated IR-weld seam control.

  16. SOS-Racisme, histoire d'une mobilisation "apolitique". Contribution à une analyse des transformations des représentations politiques après 1981

    OpenAIRE

    Juhem, Philippe

    1998-01-01

    The emergence of militant organizations or new political movements always seems rather strange and accidental : why do a number of movements generate particularly strong commitments and find numerous relays, whereas others find it difficult to make themselves known and widen their audience beyond the initial circle of their founders ? This thesis about SOS-Racism – a French antiracist movement founded in 1984 – originated from a question about the conditions of success in politics. Why, at th...

  17. Les qualités royales des Ptolémées d’après leurs noms officiels grecs

    OpenAIRE

    Sales, José das Candeias

    2010-01-01

    Que représentent et que signifient, en termes de propagande royale, les prédicats et noms des Lagides? Quels «sentiments dynastiques» et quelles qualités de pouvoir sont-ils diffusés et invoqués par l’onomastique de culte hellénique de ces seigneurs de l’Egypte? À quel ensemble de notions et de conceptions renvoient-ils et quelles vertus communiquent-ils? Il s’agit de quelques-unes des questions auxquelles nous avons cherché à répondre dans ce texte. Si l’on se place sous le prisme de leu...

  18. L’exportation de bois précieux (Dalbergia et Diospyros « illégaux » de Madagascar : 2009 et après ?

    Directory of Open Access Journals (Sweden)

    Pascal Lopez

    2010-12-01

    Full Text Available Illegal rosewood logging has known a strong increase in 2009, following two inter-ministerial texts legalizing exports of precious wood. National parks are specifically affected by this exploitation. It is of course very difficult to know the real situation concerning exploitation but also exports. This paper presents and discusses information about “illegal” exports. Firstly, after a recall of the legal context, it underlines the difficulties in collecting information. Several reasons are underlined: the size of container, the density of wood, the diversity of material (log, board, etc, the place of shipment, the filling up of containers, and under-declaration for fiscal reasons. Nevertheless, even if exports estimations are probably far from the reality, the equivalent of around 1,202 containers, representing a value of more than US$ 220,000,000 are listed. Secondly, it analyzes also traffic regulation systems. More specifically, it proposes a parallel between the regulation of ivory traffic and the regulation of precious wood traffic in Madagascar. It concludes that the process of garnishment with resale by auction has very few chances to be efficient. The ivory case shows that reinforcing processes of garnishment do not succeed in stopping the traffic. It rather provokes reorganizations of the value chain. In the long term, the sole solution will be the development of a sustainable labeled chain for precious wood. European Union Due Diligence Regulation and Lacey Act in United States participate in the strengthening of control on precious wood.

  19. Impaired epithelial differentiation of induced pluripotent stem cells from ectodermal dysplasia-related patients is rescued by the small compound APR-246/PRIMA-1MET

    OpenAIRE

    Shalom-Feuerstein, Ruby; Serror, Laura; Aberdam, Edith; Müller, Franz-Josef; Van Bokhoven, Hans; Wiman, Klas G.; Zhou, Huiqing; Aberdam, Daniel; PETIT Isabelle

    2013-01-01

    Ectodermal dysplasia is a group of congenital syndromes affecting a variety of ectodermal derivatives. Among them, ectrodactyly, ectodermal dysplasia, and cleft lip/palate (EEC) syndrome is caused by single point mutations in the p63 gene, which controls epidermal development and homeostasis. Phenotypic defects of the EEC syndrome include skin defects and limbal stem-cell deficiency. In this study, we designed a unique cellular model that recapitulated major embryonic defects related to EEC. ...

  20. The radiance of France; nuclear power and national identity after world war 2; Le rayonnement de la France; energie nucleaire et edentite nationale apres la seconde guerre mondiale

    Energy Technology Data Exchange (ETDEWEB)

    Hecht, G. [Michigan Univ., Ann Arbor, MI (United States)

    2004-07-01

    This book discusses the early history of French nuclear power within its social and political context from the end of world war 2 to 1970. The author describes the creation of the nuclear reactors, the work at the reactor sites, and the impact of nuclear power on local communities. Information on the French atomic bomb program is also included. The conflicts and negotiations surrounding the nuclear programs are detailed, and the importance of the programs to French national identity is made clear. An excellent bibliography and extensive footnotes are provided.

  1. Retour sur la série type de Gomphotherium angustidens (Proboscidea, Mammalia: de Daubenton à Cuvier, et après

    Directory of Open Access Journals (Sweden)

    Göhlich, U. B.

    2011-12-01

    Full Text Available We analyze the specimens used by Cuvier to describe in 1806 his «mastodonte à dents étroites», named by him Mastodon angustidens later in 1817. Some of them – molars and partial molars from Simorre (Gers – were already mentioned by Réaumur and Daubenton during the 18th century. What is considered as the original type series of Gomphotherium angustidens (CUVIER, 1817 is presented and newly interpreted.[fr] Les spécimens qui ont permis à Cuvier de décrire le «mastodonte à dents étroites» en 1806, dénommé par lui Mastodon angustidens en 1817, sont révisés. Certains d’entre eux (molaires et fragments de molaires, provenant de Simorre (Gers, avaient déjà été mentionnés par Réaumur et par Daubenton au 18e siècle. La série type de Gomphotherium angustidens (CUVIER, 1817 est présentée, discutée et réinterprétée.

  2. Comment financer le développement après la crise économique et financière

    Directory of Open Access Journals (Sweden)

    Bruno Gurtner

    2011-05-01

    Full Text Available La crise a eu, sur les taux de croissance des pays en développement ou émergents, des effets plus dévastateurs que sur ceux des nations industrialisées. Alors que certains n’avaient pas les ressources nécessaires pour financer des mesures de relance assez vigoureuses, les grands pays émergents ont vite retrouvé le chemin de la reprise et sont actuellement les principaux moteurs de l’économie mondiale.L’effondrement des flux de capitaux privés a provoqué un déficit croissant dans le financement global du Sud. Et jusqu’à présent, pas plus l’augmentation des flux financiers publics que la lente reprise – depuis la fin 2009 – des apports de capitaux privés n’ont permis de compenser ces manques. L’ONU indique par ailleurs que le volume global des mouvements financiers des pays du Sud vers ceux du Nord dépasse celui des flux en sens contraire : le Sud continue de financer le Nord.Alors que l’on débat désormais d’une réforme de l’ordre économique et financier mondial, cela n’a pas encore été suivi d’effets suffisants pour les pays en développement. Les institutions financières internationales disposent bien de ressources accrues, mais les pays en développement y sont toujours sous-représentés. Le FMI et la Banque mondiale ont remis en question certains de leurs dogmes traditionnels, sans que l’on puisse parler à coup sûr de nouvelle politique.Il apparaît toujours plus évident que les impôts jouent un rôle central dans la mobilisation de ressources locales pour financer le développement et l’on reconnaît d’une manière générale qu’il faudra réformer dans ce sens la fiscalité des pays en développement. Cependant, l’aide technique des pays industrialisés en vue de réaliser ces réformes reste insuffisante. De même, il est de plus en plus admis que les impôts sont un instrument pour la construction de l’Etat (state-building, la démocratisation et la gouvernance. La lutte contre l’évasion fiscale à l’échelle internationale et les flux illicites de capitaux (illicit capital flows a gagné en vigueur et l’on voit s’améliorer les échanges d’informations en matière fiscale. Mais les instruments novateurs et plus efficaces d’une transparence accrue ont de la peine à s’imposer face aux intérêts occultes de certains centres financiers.

  3. The LasB Elastase of Pseudomonas aeruginosa Acts in Concert with Alkaline Protease AprA To Prevent Flagellin-Mediated Immune Recognition

    OpenAIRE

    Casilag, Fiordiligie; Lorenz, Anne; Krueger, Jonas; Klawonn, Frank; Weiss, Siegfried; Häussler, Susanne

    2015-01-01

    The opportunistic pathogen Pseudomonas aeruginosa is capable of establishing severe and persistent infections in various eukaryotic hosts. It encodes a wide array of virulence factors and employs several strategies to evade immune detection. In the present study, we screened the Harvard Medical School transposon mutant library of P. aeruginosa PA14 for bacterial factors that modulate interleukin-8 responses in A549 human airway epithelial cells. We found that in addition to the previously ide...

  4. Radiotherapy for PSA failure after prostatectomy: which volumes?; Radiotherapie pelvienne pour recidive biochimique isolee apres prostatectomie pour cancer de prostate: quels volumes?

    Energy Technology Data Exchange (ETDEWEB)

    Bosset, M.; Maingon, P. [Centre Georges-Francois-Leclerc, Service de Radiotherapie, 21 - Dijon (France); Bosset, J.F. [Centre Hospitalier Universitaire Jean Minjoz, Service de Radiotherapie, 25 - Besancon (France)

    2006-05-15

    After prostatectomy, radiotherapy is a potential curable treatment. From the surgery series, it is possible to identify all the localization at risk in case of biochemical relapse after prostatectomy. The target volume of irradiation has to be defined according to the pathological findings. The CTV is limited to the pelvic fascia laterally, to the anterior wall of the rectum behind. The inferior limit includes the anastomosis, and the superior is easier to define with the length of the prostatic gland. The inclusion of area of seminal vesicles and pelvic node areas should be discussed. The use of surgical clips on the anastomosis and image fusion techniques including the preoperative imaging would help physicians to define the CTV's limits. (authors)

  5. Sympathetic re-innervation of myocardium after liver transplant in the hereditary amyloid neuropathy; Reinnervation sympathique du myocarde apres transplantation hepatique dans la neuropathie amyloide hereditaire

    Energy Technology Data Exchange (ETDEWEB)

    Delahaye, N.; Le Guludec, D. [Medecine Nucleaire, Hopital Bichat, Paris (France); Slama, M. [Cardiologie, Hopital A.Beclere, Paris (France); Guyen, C.N. [SHFJ, DSV-CEA, Orsay (France); Dinanian, S. [Cardiologie, Hopital A.Beclere, Paris (France); Merlet, P. [SHFJ, DSV-CEA, Orsay (France)

    1997-12-31

    The hereditary amyloid neuropathy (HAN) is characterized by a progressive sensory-motor poly-neuropathy and a dysautonomia with myocardium sympathetic denervation. This is established by MIBL scintigraphy and may enhance the troubles of conduction and of cardiac rhythm. The amyloid deposits are constituted of anomalous pre-albumin fabricated by liver. The hepatic transplant (HT) is the only known treatment. Four patients (GI: 39 {+-} 5 years) have been studied by MIBG scintigraphy, 2.2 {+-} 0.7 years after HT, and compared with 12 patients (GII: 39 {+-} 12 years) studied before HT. The left ventricular function, the coronary arteries and the at-rest scintigraphy with thallium were normal for all of them. The cardiac capture of MIBG, evaluated by the cardio-mediastinal activity ratio (C/M), measured on an anterior thoracic planar acquisition performed 4 hours after the intravenous injection of 300 MBq, was higher for GI than for GII (1.49 {+-} 0.12 vs 1.29 {+-} 0.13, p 0.02). The washouts (4 h / 20 min) were not different. In tomography, the patients of GI presented focal anomalies with a more-or-less extended apical defect, a satisfying fixation of the basal half of the anterior wall, more-or-less overflowing the septal and lateral walls, and for 2 patients, a satisfying inferior fixation. On the contrary, 9/12 patients of GII have had a diffuse absence of fixation, the other three heaving a satisfying antero-basal fixation ({chi}{sup 2}, p = 0.05). The results are not explained by difference of severity or evolution duration of HAN. Thus, it appears that there exists a sympathetic re-innervation of myocardium after HT in the HAN, debuting by the heart base, similarly with the effect of anatomic interruption of innervation in cardiac transplants

  6. Geological and chemical data collected around Gaillard Island, Mobile Bay, Alabama from 11 Apr 1980 to 25 Aug 1982 (NODC Accession 0117688)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Sediment samples were collected from four sites around Gaillard Island, quarterly in 1980 and monthly in 1981-1982, and analyzed for particle size characteristics,...

  7. The use of confocal microscopy in lung anatomy-pathology after local irradiation; Apports de la microscopie confocale en anatomie-pathologique pulmonaire apres irradiation locale

    Energy Technology Data Exchange (ETDEWEB)

    Dudoignon, N.; L' Hullier, I.; Guillet, K.; Frot, C.; Poncy, J.L.; Fritsch, P. [CEA Centre d' Etudes de Bruyeres-le-Chatel, 91 (France)

    1998-04-01

    Methods have been developed to quantify fibrosis and proliferative lesions in the lungs They combine, on the same sample, confocal microscopy on thick sections and conventional microscopy on thin sections. (authors)

  8. 'Grenelle de l'environnement': climate and energy: a year later; Grenelle de l'environnement, climat et energie: un an apres

    Energy Technology Data Exchange (ETDEWEB)

    Grandjean, A. [Carbone 4, 75 - Paris (France); Criqui, P. [Centre National de la Recherche Scientifique (CNRS-LEPII), 38 - Grenoble (France)

    2008-05-15

    The Grenelle de l'environnement has marked an important date in the development of France's environmental policy. It showed in particular that different stakeholders, from NGOs to trade unions including companies, authorities and administrations, were capable of converging on specific objectives, at once ambitious and realistic. But whilst the dangers- relating to petroleum and climate - are made clearer, today it seems the process is hovering midstream. The signal for environmental taxation, which will enable the energy transition to be prompted has still not been given. The introduction of a climate/energy contribution continues to be the long-term solution. Adapted recycling methods would mean its impacts on purchasing power and company competitiveness could be controlled. (authors)

  9. SFEN Annual Convention 2012 - The nuclear energy one year after Fukushima. Proceedings; Convention SFEN 2012 - Le nucleaire un an apres Fukushima. Recueil des presentations

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-03-15

    This document brings together the available presentations given at the 2012 edition of the Annual Convention of the French society of nuclear energy (SFEN) on the topic of nuclear energy one year after Fukushima. Twenty four presentations (slides) are compiled in this document: 1 - Presentation and introduction of the Annual Convention (Luc Oursel - SFEN President); 2 - Status of onsite/offsite remedial actions, key lessons learned (Akira Omoto, Tokyo univ., Japan Atomic Energy Commission); 3 - Complementary Safety Assessments (CSA) of the French NPP fleet (Dominique Miniere, EDF); 4 - Speech of M. Francois Fillon - Prime Minister; 5 - CSA of the fuel cycle facilities (Philippe Knoche, Areva); 6 - CSA of the EPR (Bertrand de l'Epinois, Areva; Jean-Luc Foret, EDF CNEN); 7 - The collective responsibility of the operators: the action of WANO (Laurent Stricker, WANO); 8 - Conclusions of French Nuclear Safety Authority (ASN) - Safety measures to be strengthened; 9 - Opinion no. 2012-AV-013 from January 3, 2012 of the French Nuclear Safety Authority - ASN (Sophie Mourlon, ASN; Caroline Lavarenne, IRSN); 10 - Nuclear energy: an energy for the future (Bernard Bigot, CEA); 11 - The nuclear phaseout in Germany from the view of German industry (Eberhard von Rottenburg, BDI); 12 - Prospects in China (Wei Lu, CGNP Europe); 13 - Industry Current Status and its Prospects in the United States (J. Spina, CENG); 14 - Nuclear energy prospects in France: recommendations of the Commission 'Energy 2050' (Jacques Percebois, Creden); 15 - Electrical generation system efficiency and economy (Yves Giraud, EDF); 16 - Electrical generation systems and distribution networks (Herve Mignon, Rte); 17 - Prospects in the UK (Tim Stone, DECC/OND, Senior Adviser to the Secretary of State); 18 - Climatic changes and energy policy (Laura Cozzi, IEA); 19 - The young nuclear professionals network (Boris Supiot, SFEN Young Generation Group); 20 - Socio-economic impacts of the nuclear power industry in France (Philippe Girault, PricewaterhouseCoopers); 21 - Public acceptance, different sectors, identical behaviours (Claudia Gross, Resosens); 22 - Conclusion (Dominique Miniere, SFEN); Additional presentations: 23 - The Fukushima Daichi accident (Peter Volkholz, Areva NP GmbH); 24 - Impact on the public and on the environment (Philippe Renaud, IRSN)

  10. Désulfuration : avant, pendant ou après la combustion ? Synthèse bibliographique Desulfurization: Before, During Or After Combustion? Bibliographic Synthesis

    Directory of Open Access Journals (Sweden)

    Benchecroun N.

    2006-11-01

    Full Text Available Les perspectives d'applications de nouvelles normes aux émissions des grandes installations de combustion, tant aux Etats-Unis qu'en Europe de l'Ouest ont suscité de nombreuses recherches. Les diverses publications qui leur sont consacrées traitent le plus souvent de la combustion de charbons et, beaucoup plus rarement, de l'adaptabilité de ces procédés à des combustibles liquides ou de techniques spécifiques. Les principaux points technico-économiques qui se dégagent sur la désulfuration des combustibles liquides sont donnés dans cet article. Enfin, au-delà des aspects techniques, on notera que la désulfuration des combustibles liquides, et plus particulièrement du fuel lourd, est liée à deux aspects plus politiques : - l'application de normes sur les émissions des installations de combustion (ou les dérogations possibles qui concernent non seulement les oxydes de soufre mais aussi les oxydes d'azote et les particules contenues dans les fumées; - l'avenir des fuels lourds tant sur le plan quantitatif (marché que qualitatif (constitution du pool fuel et spécifîcations. The prospects that new emission standards will be applied to large combustion installations, both in the United States and Western Europe, have given rise to extensive research. The different publications devoted to this research usually deal with coal combustion and more rarely with the suitability of such processes for liquid fuels or specific techniques. The leading technico-economic points involved in the desulfurization of liquid fuels are given in this article. Likewise, over and beyond the technical aspects, it can be seen that the desulfurization of liquid fuels, and more particularly of heavy fuel oil, is linked to two more politicalaspects:(a the application of standards on emissions from combustion installations (or possible derogations concerning not only sulfur oxides but also nitrogen oxides and particles contained in fumes;(b the future of heavy fuel oils from the quantitative (market as well as qualitative (composition of the fuel-oil pool and specifications standpoints.

  11. [52th Commemoration of French Journal of Plastic Aesthetic Surgery (1956-2007). Fifty-four years of editorial; five Editors-in-chief].

    Science.gov (United States)

    Cariou, J-L

    2007-08-01

    The french Society of Plastic Reconstructive and Aesthetic Surgery (SOF.CPRE) is born December 3th 1952. Initially without "aesthetic", this "key-word" is agreed in 1983 and the symbols are advanced since: SFCPR, SFCPRE, SOF.CPRE. Its official organ, formerly included in Annales de chirurgie (1954-1955), become Annales de chirurgie plastique in 1956, Annales de chirurgie plastique et esthétique in 1983 and finally Annales de chirurgie plastique esthétique (ACPE) in 1992. Since the origin, five Editors-in-chief succeded: Claude Dufourmentel, Raymond Vilain, Jean-Pierre Lalardrie, Claude Lê-Quang, Jean-Luc Cariou. Four of them are alive, Raymond Vilain is dead. The author relate here the natural story of these five editors who had all a triple route: personnal, surgical and editorial.

  12. Brahmsi "Saksa reekviem" Eestis / Kersti Inno

    Index Scriptorium Estoniae

    Inno, Kersti, 1954-

    2007-01-01

    Eesti Filharmoonia Kammerkoori ja Eesti Riikliku Sümfooniaorkestri kontserdist 3. apr. Vanemuise kontserdimajas, 4. apr. Jõhvi kontserdimajas, 6. apr. Estonia kontserdisaalis ja 7. apr. Pärnu kontserdimajas

  13. Siim Nestor soovitab : David Morales. Reede ja laupäeva parimad palad / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-

    2004-01-01

    Popmuusikaüritustest: David Morales 15. apr. klubis Moskva, "Eklekter" 16. apr Von Krahlis (esinejaks rootsi diskor DJ Mad Mats), prantsuse diskor DJ Yellow 16. apr. klubis Hollywood, üritusest "Dependent" 17. apr. Tartus

  14. Ülestõusmispühad barokkmeistrite suurteostega / Kersti Inno

    Index Scriptorium Estoniae

    Inno, Kersti, 1954-

    2006-01-01

    G. F. Händeli "Ülestõusmisoratooriumi" ettekandest 16. apr. Estonia kontserdisaalis. J. S. Bachi "Missa h-moll" ettekandest 13. apr. Jõhvi kontserdimajas, 14. apr. Estonia kontserdisaalis, 15. apr. Pärnu kontserdimajas

  15. Siim Nestor soovitab : DJ Marky. Marco Passarani. Padded Cell / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-

    2006-01-01

    Drum'n'bassi peost "Jus'Fine" 20. apr. klubis Privé Tallinnas. Technomuusikapeost "Stereo88" 20. apr. Tartus klubis Illusion ja 21. apr. Tallinnas Von Krahlis. Üritusest "Mutant Disko" 21. apr. klubis Privé

  16. Seitse miljardit veemajandusele / Rein Randver

    Index Scriptorium Estoniae

    Randver, Rein, 1956-

    2007-01-01

    Ilmunud ka: Sakala, 3. apr. 2007, lk. 2; Võrumaa Teataja, 3. apr. 2007, lk. 2; Vooremaa, 3. apr. 2007, lk. 2; Vali Uudised, 4. apr. 2007, lk. 2; Meie Maa, 4. apr. 2007, lk. 2; Põhjarannik, 4. apr. 2007, lk. 2; Severnoje Poberezhje, 4. apr. 2007, lk. 2; Harju Ekspress, 5. apr. 2007, lk. 8; Harjumaa, 5. apr. 2007, lk. 4; Lääne Elu, 10. apr. 2007, lk. 2; Oma Saar, 13. apr. 2007, lk. 5. Ametist lahkuv keskkonnaminister peab kõige olulisemaks ja rahaliselt suuremahulisemaks tegevusvaldkonnaks veemajandust

  17. Einfluss des Pneumoperitoneums auf die Ultrastruktur des Peritoneums

    OpenAIRE

    Jakob, Jens

    2004-01-01

    Hintergrund: Der Einsatz minimal invasiver Techniken in der onkologischen Chirurgie wird wegen der Berichte über Trokarmetastasen kontrovers diskutiert. Die Pathogenese von Inzisionsmetastasen und intraperitonealem Tumorwachstum ist bisher nicht bekannt. Als mögliche Ursachen kommen bei Einsatz der laparoskopischen Chirurgie auch Einflüsse von Gas und Druck auf das Peritoneum in Betracht. Dabei könnte eine peritoneale Inflammation die Adhäsion und das Wachstum von Tumorzellen begünstigen. Wir...

  18. Valgevenelased väärivad demokraatiat / Marianne Mikko

    Index Scriptorium Estoniae

    Mikko, Marianne, 1961-

    2008-01-01

    Ilmunud ka: Vooremaa, 5. apr., lk. 2 Pärnu Postimees 5. apr., lk. 19, Järva Teataja 5. apr., lk. 2, Põhjarannik 5. apr., lk. 2, Severnoje Poberezhje 5. apr. lk. 2, Meie Maa 8. apr. lk. 2, Koit 8. apr. lk. 6, Sakala 15. apr. lk. 8. Europarlamendi saadik kirjutab oma tööst Poolast edastatava Valgevene telejaama Belsat toetamisel ning võitlusest Valgevenes valitseva diktatuuri vastu

  19. Metsandust räsivad karmid reformid / Karel Rüütli

    Index Scriptorium Estoniae

    Rüütli, Karel, 1978-

    2008-01-01

    Ilmunud ka: Nädaline 22. apr. lk. 4, Hiiu Leht 22. apr. lk. 2, Võrumaa Teataja 22. apr. lk. 2, Tartu Postimees 28. apr. lk. 2, Vooremaa 29. apr. lk. 2, Nädalaleht 30. apr. lk. 5. Parlamendiliikme sõnul on Rahvaliit RMK ennatlike reformide vastu, millega satub ohtu 50 elujõulist metsandusasulat üle Eesti

  20. Re-irradiation after salvage mastectomy for local recurrence after a conservative treatment: a retrospective analysis of twenty patients (Nancy: 1988-2001); Re-irradiation parietale apres mastectomie de rattrapage pour recidive d'un cancer du sein apres traitement conservateur: etude retrospective sur 20 patientes (Nancy: 1988-2001)

    Energy Technology Data Exchange (ETDEWEB)

    Racadot, S.; Marchal, C.; Charra-Brunaud, C.; Peiffert, D.; Bey, P. [Centre Alexis-Vautrin, Service de Radiotherapie, 54 - Vandoeuvre-les-Nancy (France); Verhaeghe, J.L. [Centre Alexis-Vautrin, Service de Chirurgie, 54 - Vandoeuvre-les-Nancy (France)

    2003-12-01

    Purpose. - To retrospectively assess the efficacy of post-mastectomy re-irradiation for local relapse of breast cancer. Patients and methods. - Twenty patients, initially treated by conservative surgery and radiotherapy (50 Gy in 25 fractions over 5 weeks) were treated from 1998 to 2001 for a local relapse by salvage mastectomy and re-irradiation (either electron or photon beams). Mean age was 53 years (31-71). Reasons for re-irradiation were that the local relapses were inflammatory (4 pts), multifocal (5 pts), cutaneous (5 pts), involved the nipple (3 pts) or because the surgical margins (either muscle or skin) were involved (3 pts). The median dose of re-irradiation was 45 Gy (33-65) in 15 fractions over 33 days. Mean follow-up was 48 months (5-97). Results. - Fifteen patients remained free of a second local recurrence and 10 were still alive, without metastasis. Neither the dose of re-irradiation nor the irradiated surfaces were prognostic factors of local control (P = 0.877 and P = 0.424). Five patients developed radiation-induced pneumonitis without functional respiratory impairment. The incidence of pneumonitis seemed to be related to the biological dose of re-irradiation (P = 0.037). Other late complications occurred such as pigmentation changes (12 pts), telangiectasia (8 pts), chondritis (2 pts), parietal fibrosis (7 pts), rib fractures (4 pts), severe pain (11 pts) and lymphedema (2 pts). The increase in biological equivalent dose was highly statistically linked with the occurrence of disabling pain (P = 0.0123). Conclusion. - Parietal re-irradiation achieves good and lasting local control with an acceptable rate of acute complications but with a risk of disabling late sequelae such as severe pain. (author)

  1. Assessment of risks associated to ionizing radiations: lung cancers after domestic radon exposure and thyroid cancers after accidental exposure to radioactive iodines; Evaluation des risques associes aux rayonnements ionisants: cancers du poumon apres exposition domestique au radon et cancers de la thyroide apres exposition accidentelle aux iodes radioactifs

    Energy Technology Data Exchange (ETDEWEB)

    Catelinois, O

    2004-09-15

    The aim of this work is to develop a critical analysis of quantitative risk assessment in the field of ionizing radiation and to provide new estimates of attributable risks for particular situations of environmental exposure to ionizing radiation. This work is based on knowledge about dose-response relationships and ionizing radiation exposure of the general population. The work focuses on two different situations that both present an important interest for public health: lung cancer associated with domestic radon exposures (natural situation) and thyroid cancer associated with the Chernobyl accident fallout (accidental situation). The assessment of lung cancer risk associated with domestic radon exposure considers 10 dose-response relationships resulting from miner cohorts and case-control studies in the general population. A critical review of available data on smoking habits has been performed and allowed to consider the interactions between radon and tobacco. The exposure data come from measurements campaigns carried out since the beginning of the 1980 by the Institute for Radiation protection and Nuclear Safety and the Health General Directory in France. The French lung cancer mortality data are provided by the I.N.S.E.R.M.. Estimates of the number of attributable cancers are carried out for the whole country, stratified by 8 large regions (Z.E.A.T.) and by 96 departments for the year 1999 allowing to perform a sensibility analysis according to the geographical level of calculation. Uncertainties associated to risk coefficients and exposures have been quantified and it's impact on risk estimates is calculated. The estimated number of deaths attributable to domestic radon exposure ranges from 543 (90% uncertainty interval (U.I.): 75-1,097) to 3,108 (90% U.I.: 2,996-3,221). The corresponding risk fractions range from 2.2% (90% U.I.: 0.3%-4.4%) to 12.4% (90% U.I.: 11.9%-12.8%). The assessment of thyroid cancer risk in the most exposed area of France due to the Chernobyl nuclear power plant accident fallout, is based on the excess relative risk model published by E. Ron et al. in 1995. The target population is composed of all children younger than 15 years and living in the eastern part of France at the time of the accident (26 April 1986). The incidence rates between 1978 and 1997 are analysed and forecasted up to 2007 using age-period-cohort models. Thyroid doses are estimated from all available data about the contamination in France from the Chernobyl fallout/ The risks characterization is carried out by considering various scenarios on the projection of spontaneous incidence rates, the effectiveness of internal exposures compared to external ones and the levels of radioactive deposits. Uncertainties to the risk coefficient, the expected spontaneous incidence rates and the thyroid dose are considered. The estimated number of thyroid cancer cases in excess between 1991 and 2007 for the target population ranges from 5 (90% U.I.: 1-15) to 63 (90% U.I. 12-180). In comparison, depending on the scenario of spontaneous rate projection, the number of spontaneous cancer cases should range from 894 (90% U.I.: 869-920) to 1,716 (90% U.I.:1,691-1,741) between 1991 and 2007. The results show that the thyroid cancer incident rate increase observed in France during last 20 years cannot be explained by the Chernobyl fallout. The work provides an adaptation of the classical risk assessment method integrating each of its step such as a discussion about the choice of the dose-response relationship. The data analysis considers the interaction between ionizing radiation and other risk factors, a spontaneous incidence rate projection and a quantification of uncertainties. This work provides new results showing the importance of the choice of the dose-response relationship, of the consideration of the spontaneous incidence trend and of the quantification of uncertainties in risk assessment. In conclusion, this work provides new knowledge for public health by the analysis of enlarged epidemiological data. (author)

  2. Public Forum Before the Committee on Urban Indians in L.A., Calif. (Dec. 16-17, 1968); Dallas, Tex. (Feb. 13-14, 1969); Minneapolis-St. Paul, Minn. (Mar. 18-19, 1969); San Francisco, Calif. (Apr. 11-12, 1968); Phoenix, Ariz. (Apr. 17-18, 1969).

    Science.gov (United States)

    National Council on Indian Opportunity, Washington, DC.

    The proceedings of public forums of the National Council of Indian Opportunity are recorded in these 5 documents. These forums were designed to gain information on the condition of urban American Indians living in Los Angeles, Minneapolis-St. Paul, San Francisco, Dallas, and Phoenix. Included in each of the documents are discussions on such…

  3. Lähme, naised / Tiina Kuuler

    Index Scriptorium Estoniae

    Kuuler, Tiina, 1969-

    2008-01-01

    Muusikasündmustest: Rebecca "Inglite pisarad" 10. apr. Tallinnas Toompeal Nelipühi kirikus, "Puhkpilliorkester Tartu 60" 6. apr. Vanemuise kontserdimajas, Singer-Vinger 4. apr. Tallinnas Rock Cafés, "Kolumbus Kris 21" 11. apr. Rock Cafés, "Rock & Roll City" 5. apr. Rock Cafés, Voiceboys 4. apr. Vanemuise kontserdimajas, 5. apr. Jõhvi kontserdimajas ja 6. apr. Estonia kontserdisaalis, "The Musigue Bazaar" 4. apr. Tartus baaris Tige Tikker, Clubarena sünnipäev 4. apr. Tallinnas Mustpeade majas (vt. www.clubarena.com)

  4. Tuumajaam Eestisse - otstarbekas ja paratamatu? / Harri Õunapuu

    Index Scriptorium Estoniae

    Õunapuu, Harri, 1947-

    2008-01-01

    Ilmunud ka: Hiiu Leht 11. apr., lk. 2, Harju Ekspress 11. apr., lk. 6, Sakala 11. apr., lk. 2, Kuulutaja 11. apr. lk. 4, Elva Postipoiss 12. apr., lk. 4, Koit 12. apr. lk. 6, Meie Maa 14. apr. lk. 2, Järva Teataja 15. apr. lk. 2, Põhjarannik 16. apr., lk. 2, Severnoje Poberezhje 16. apr. lk. 2, Vooremaa 19. apr. lk. 2, Lääne Elu 26. apr. lk. 2, Paremad Uudised apr. nr. 3 lk. 7, Virumaa Teataja 26. juuni lk. 11, Nädalaleht 11. apr. lk. 2. Riigikogu liikme hinnangul on tuumaenergia kui praktiliselt heitmevaba energialiik tõsiseltvõetav alternatiiv Eesti heitainemahuka elektritootmise nüüdisajastamisel. Riigikogu peaks vastu võtma põhimõttelise seisukoha tuumaenergeetika osas

  5. Viiuldaja avardab ruumi- ja ajamõõdet

    Index Scriptorium Estoniae

    2008-01-01

    Viiuldaja Tiit Kikas annab aprillis Eesti eri paigus üheksa kontserti (kõlavad ka albumi "String Theory" kompositsioonid, kontserdid toimuvad 18. apr. Tallinnas Von Krahli teatri saalis, 19. apr. Kuressaare Linnateatris, 23. apr. Viljandis Eesti pärimusmuusika keskuse väikeses saalis, 24. apr. Tartus Athena keskuses, 25. apr. Türi kultuurimajas, 26. apr. Rakvere teatri väikeses saalis ja 27. apr. Jõhvi kontserdimaja kammersaalis)

  6. Siim Nestor soovitab : Rulers of the Deep. Tartu Popi ja Roki Instituut. Väliskülalised / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-

    2006-01-01

    Duo Rulers of the Deep heliplaadi "Next Evolution" esitlustest 28. apr. Ranna klubis Sillamäel, 29. apr. klubis Hollywood Tallinnas, 30. apr. Rakvere teatrikohvikus, 5. mail klubis Privé Tallinnas, 6. mail klubis Illusion Tartus. Ansambli Tartu Popi ja Roki Instituut esikalbumi "Madise margikogu" esitlusest 29. apr. Sõbra Majas Tartus. James Mowbray 28. apr. klubis Privé Tallinnas ja 29. apr. klubis Illusioon, Maga Mo peol "Bassikultuur" 28. apr. Von Krahlis Tallinnas

  7. Lähme, naised / Tiina Kuuler

    Index Scriptorium Estoniae

    Kuuler, Tiina, 1969-

    2008-01-01

    Muusikasündmustest: "Levimuusikapäevad" 24.-27. apr. Tartus Genialistide klubis Lutsu teatrimajas, "Peda Folk" 22. apr. Tallinnas Kultuurikatlas (Põhja pst 27a), etnosari "Sotto Voce" 23. apr. Estonia Talveaias, kontsert "Sotspop 2008" 26. apr. Tallinna linnahallis, Jüripäeva kontsert 23. apr. Tallinna Jaani kirikus, Bonzo ja Tõun "Soojad laulud" 18. apr. Pirita Vaba Aja Keskuses, The Suni uue plaadi esitlus 19. apr. Tallinnas Rock Cafes

  8. Les fractures distales de la clavicule type II de Neer: plaque à crochet versus brochage transacromiale

    Science.gov (United States)

    Mechchat, Atif; Elidrissi, Mohammed; Shimi, Mohammed; Elibrahimi, Abdelhalim; Elmrini, Abdelmajid

    2015-01-01

    Cette étude a été menée afin de faire une comparaison entre deux techniques chirurgicales différentes: la plaque à crochet et l'embrochage dans les fractures instables du quart externe de la clavicule. Nous avons mené une étude prospective entre 2009 et 2013, incluant deux groupes de patients: un premier groupe de 14 patients traités par plaque à crochet par voie d'abord antéro-inférieure, un second de 12 patients traités par brochage. Tous les patients ont été hospitalisés 24 h après la chirurgie et ont été suivi pendant 1 an. Nous avons comparé les résultats des deux techniques en étudiant: le temps opératoire, le saignement, délai de consolidation, la douleur et la fonction selon le score de constant. L'analyse statistique des résultats fonctionnels et radiologiques a montré la supériorité d'une technique par rapport à l'autre; ainsi l’âge moyen global était de 32,6 ans (+/- 13,7), le sex-ratio (H/F) était de 1. Le temps opératoire moyen est de 35 min pour la plaque à crochet contre 45 minutes pour le brochage, le délai moyen de consolidation était de 6,1 (+/-0,7) semaines dans le groupe traité par plaque vissée, et de 6 (+/-0,7) semaines dans le groupe traité par embrochage (p = 0,5), le score de Constant absolu moyen était respectivement de 86 (+/-10,4) et de 90,92 (+/-2,5) (p = 0,04). L'analyse uni variée a montré une association statistiquement significative entre les paramètres d’évaluation et les deux techniques chirurgicales étudiées. Par conséquent, l’étude a noté la supériorité de la plaque à crochet contre l'embroche dans les fractures instables du quart externe de la clavicule. PMID:26090053

  9. Les séquelles de brûlures cervicales: aspects épidémiologique, clinique et thérapeutique au Maroc

    Science.gov (United States)

    Rafik, Amine; Chabak, Hakim; Diouri, Mounia; Bahechar, Naïma; Chlihi, Abdessamad

    2015-01-01

    Les séquelles de brûlures cervicales représentent une entité fréquente des séquelles de brûlure, elles affectent la fonction, l'esthétique et l’état psychologique des patients et peuvent être de traitement difficile. Il s'agit d'une étude rétrospective étalée sur 5 ans de Mars 2009 au Octobre2014, réalisée au centre national des brûlés et de chirurgie plastique au CHU Ibn Rochd Casablanca. Nous avons analysé les caractéristiques épidémiologiqueset cliniques ainsi que les indications et les résultats thérapeutiques chez 300 patients présentant des rétractions cervicales post-brûlure, suivis dans notre formation. Les jeunes femmes étaient le plus souvent touchées (56%). la brûlure thermique par flamme de butane dans le cadre d'accident domestique était l’étiologie la plus fréquente (91%).75% des patients ont été pris en charge dans un délai de 18 mois après avoir présenté une incapacité fonctionnelle. Les brides cervicales modérées et sévères sont les plus fréquentes et représentent respectivement 60% et 16% des cas. Le traitement chirurgical a fait appel aux greffes cutanées dans 67%des cas, aux plasties locales dans 24%des cas et aux lambeaux dans 24% des cas, les résultats sont jugés bons dans 75%des cas et moyens dans 18% des cas, tandis que les cas restants (7%) ont nécessité une reprise chirurgicale. Le traitement des brides cervicales doit être associé à un programme de rééducation adapté, afin d'assurer la pérennité des résultats fonctionnels et esthétiques. PMID:26301017

  10. Haldusreform - mis ja milleks / Kalle Jürgenson

    Index Scriptorium Estoniae

    Jürgenson, Kalle, 1960-

    2001-01-01

    Riigi haldamise kolme tasandit - riigi keskvõimu, maakonna ja kohalike omavalitsuste tasandit - on vaja ühes või teises osas reformida. Autor: Isamaaliit. Parlamendisaadik. Ilmunud ka: Võrumaa Teataja, 10. apr. 2001, lk. 2; Põhjarannik, 10. apr. 2001, lk. 2; Severnoje Poberezhje, 10. apr. 2001, lk. 2; Meie Maa, 10. apr. 2001, lk. 2; Lääne Elu, 10. apr. 2001, lk. 4; Vooremaa, 10. apr. 2001, lk. 2; Nädaline, 10. apr. 2001, lk. 5; Virumaa Teataja, 18. apr. 2001, lk. 7; Infoleht : Isamaaliit, apr., nr. 27, 2001, lk. 8

  11. Rehepapid ja peremehed / Hannes Astok

    Index Scriptorium Estoniae

    Astok, Hannes, 1964-

    2007-01-01

    Ilmunud ka: Järva Teataja, 26. apr. 2007, lk. 2; Võrumaa Teataja, 26. apr. 2007, lk. 2; Vooremaa, 26. apr. 2007, lk. 2; Põhjarannik, 26. apr. 2007, lk. 2; Severnoje Poberezhje, 26. apr. 2007, lk. 2; Lääne Elu, 26. apr. 2007, lk. 2; Pärnu Postimees, 27. apr. 2007, lk. 15; Hiiu Leht, 27. apr. 2007, lk. 2; Koit, 28. apr. 2007, lk. 6; Sakala, 8. mai 2007, lk. 2. Parlamendiliige mõtestab lahti intellektuaalse omandi päeva mõtte

  12. Ühistransport kui ühiskonna peegel / Rudolf Tigasing

    Index Scriptorium Estoniae

    Tigasing, Rudolf

    2007-01-01

    Ilmunud ka: Sakala, 10. apr. 2007, lk. 2; Nädaline, 10. apr. 2007, lk. 4; Meie Maa, 20. apr. 2007, lk. 2; Vooremaa, 10. apr. 2007, lk. 2; Põhjarannik, 11. apr. 2007, lk. 2; Severnoje Poberezhje, 11. apr. 2007, lk. 2; Koit, 12. apr. 2007, lk. 6; Lääne Elu, 14. apr. 2007, lk. 2; Tartu Postimees, 16. apr. 2007, lk. 2; Pärnu Postimees, 5. mai 2007, lk. 19; Järva Teataja, 21. juuli 2007, lk. 2. Transpordi Ametiühingu bussijuhtide sektsiooni asejuhataja Eesti bussijuhtide olukorrast

  13. Eakatele suurem kaal omavalitsustes / Tunne Kelam

    Index Scriptorium Estoniae

    Kelam, Tunne, 1936-

    2004-01-01

    Ilmunud ka: Virumaa Teataja, 16. apr. 2004, lk. 7; Põhjarannik, 16. apr. 2004, lk. 2; Severnoje Poberezhje, 16. apr. 2004, lk. 2; Hiiumaa, 17. apr. 2004, lk. 2; Koit, 20. apr. 2004, lk. 6; Pärnu Postimees, 21. apr. 2004, lk. 15; Vali Uudised, 21. apr. 2004, lk. 2; Meie Maa, 21. apr. 2004, lk. 2; Videvik, 22. apr. 2004, lk. 3; Sakala, 11. mai 2004, lk. 2. Autori arvates tuleks lõpetada vabatahtliku pensionikindlustuse rahastamine esimese samba arvelt, samuti tuleb enam kaasata eakaid inimesi otsuste tegemise protsessi ja tagada neile suuremad võimalused kohaliku elu mõjutamiseks

  14. Suhkrutrahvi maksku süüdlased / Eero Elenurm

    Index Scriptorium Estoniae

    Elenurm, Eero

    2005-01-01

    Ilmunud ka Pärnu Postimees 1. apr, lk. 15, Vali Uudised 1. apr. lk. 2, Põhjarannik 2. apr., lk. 2, Severnoje Poberezhje 2. apr., lk. 2, Valgamaalane 2. apr. lk. 2, Hiiu Leht, Võrumaa Teataja 5. apr., lk. 2, Koit 5. apr. lk. 2,6, Meie Maa 6. apr. lk. 2, Türi Rahvaleht 9. apr. lk. 4. Maksu- ja tolliameti tubli töö tulemusena ettevõtetest leitud deklareerimata suhkruvarud ei suurenda Eestile Euroopa Komisjonis määratud trahvisummat, vaid see võimaldab Eesti riigil osa trahvist sisse nõuda liigset suhkruvaru varjanud ettevõtetel

  15. Kak zamutit problemu pensii / Janno Reiljan

    Index Scriptorium Estoniae

    Reiljan, Janno, 1951-

    2001-01-01

    Vanaduspension peab olema tulu väljatöötatud aastate eest. Autor: ERL. Parlamendisaadik. Ilmunud ka: Põhjarannik, 12. apr. 2001, lk. 2; Severnoje Poberezhje, 12. apr. 2001, lk. 2; Koit, 12. apr. 2001, lk. 6; Meie Maa, 12. apr. 2001, lk. 2; Valgamaalane, 17. apr. 2001, lk. 2

  16. Kes peab meie eest unistama? / Ignar Fjuk

    Index Scriptorium Estoniae

    Fjuk, Ignar, 1953-

    2004-01-01

    Ilmunud ka: Vooremaa, 6. apr. 2004, lk. 2; Hiiumaa, 3. apr. 2004, lk. 2; Meie Maa, 7. apr. 2004, lk. 2; Pärnu Postimees, 13. apr. 2004, lk. 15; Valgamaalane, 15. apr. 2004, lk. 2. Mõtteid seoses Eesti EL-i ja NATO-ga liitumisega. Autor küsib, mis saab edasi, andes samas kaks nõuannet

  17. Vajame ümberkorraldusi / Kaia Iva

    Index Scriptorium Estoniae

    Iva, Kaia, 1964-

    2008-01-01

    Ilmunud ka: Harju Ekspress, Meie Maa 11. apr. lk. 6,2, Põhjarannik 15. apr., lk. 4, Severnoje Poberezhje 15. apr., lk. 4, Vooremaa 15. apr. lk. 2, Vali Uudised 16. apr. lk. 2. Parlamendiliige arutleb, kuidas muuta parlamendi töö senisest arusaadavamaks ja paindlikumaks

  18. Pahupidi presidendikampaania / Jaak Allik

    Index Scriptorium Estoniae

    Allik, Jaak, 1946-

    2006-01-01

    Autor leiab, et Tarvastu vallavolikogu koalitsiooni otsus presidendivalimistel Arnold Rüütlit mitte toetada on teatud erakondade negatiivne valimiskampaania. Ilmunud ka Põhjarannik, 2006/Apr/20, lk. 2 ; Meie Maa, 2006/Apr/20, lk. 2 ; Vooremaa, 2006/Apr/20, lk. 2 ; Sakala, 2006/Apr/18, lk. 2 ; Severnoje Poberezhje, 2006/Apr/20, lk. 2

  19. President Meri kutsub lapsi üles koguma mälestusi küüditamisest / Lennart Meri

    Index Scriptorium Estoniae

    Meri, Lennart, 1929-2006

    2001-01-01

    President Lennart Meri korraldab enne oma ametiaja lõppu suurejoonelise konkursi, millega kutsub 5.-11. klasside õpilasi koguma mitme põlvkonna mälestusi küüditamisest. Ilmunud ka: Postimees, 11. apr. 2001, lk. 17; Maaleht, 12. apr. 2001, lk. 8; Hiiumaa, 10. apr. 2001, lk. 1; Lääne Elu, 10. apr. 2001, lk. 5; Põhjarannik, 10. apr. 2001, lk. 7; Virumaa Teataja, 11. apr. 2001, lk. 7; Valgamaalane, 12. apr. 2001, lk. 5; Sakala, 11. apr. 2001, lk. 2; Koit, 12. apr. 2001, lk. 7; Nädaline, 12. apr. 2001, lk. 3; Meie Maa, 11. apr. 2001, lk. 2; Hiiu Leht, 12. apr. 2001, lk. 2; Eesti Kirik, 18. apr. 2001, lk. 1; Järva Teataja, 17. apr. 2001, lk. 2; Sirp, 20. apr. 2001, lk. 2; Sillamjaeskii Vestnik, 19. apr. 2001, lk. 1; Õpetajate Leht, 20. apr. 2001, lk. 10; Den za Dnjom, 20. apr. 2001, lk. 9; Narvskaja Gazeta, 26. apr. 2001, lk. 3.

  20. TBT recommends : Vera Bila. The No Smoking Orchestra. Robert Plant

    Index Scriptorium Estoniae

    2005-01-01

    Mustlasansambli Kale ja Vera Bila kontserdist 8. apr Tallinnas. Bosnia filmirežissööri Emir Kusturica ja tema ansambli No Smoking Orchestra kontserdist 12. apr. Riias. Inglise rocklaulja Robert Planti kontserdist 10. apr. Vilniuses

  1. "Kirikupühad Maarjamaal" / Kersti Inno

    Index Scriptorium Estoniae

    Inno, Kersti, 1954-

    2006-01-01

    Agentuuri Corelli Music uuest kontserdisarjast "Kirikupühad Maarjamaal". Vanamuusikaansambli Cantores Vagantes kontsertidest 13. apr. Pärnu Eliisabethi kirikus, 14. apr. Tartu Jaani kirikus ja 15. apr. Tallinna Rootsi-Mihkli kirikus

  2. Anneli Remme soovitab : Uus kontserdisari - "Kirikupühad Maarjamaal" / Anneli Remme

    Index Scriptorium Estoniae

    Remme, Anneli, 1968-

    2006-01-01

    Agentuuri Corelli Music uuest kontserdisarjast, vanamuusikaansambli Cantores Vagantes kontsertidest 13. apr. Pärnu Eliisabethi kirikus, 14. apr. Tartu Jaani kirikus ja 15. apr. Tallinna Rootsi-Mihkli kirikus

  3. Loodus ja inimesed on ühtemoodi olulised / Jaanus Tamkivi

    Index Scriptorium Estoniae

    Tamkivi, Jaanus, 1959-

    2007-01-01

    Ilmunud ka: Hiiu Leht (lüh.), 17. apr. 2007, lk. 2; Oma Saar, 17. apr. 2007, lk. 5; Harjumaa, 17. apr. 2007, lk. 2; Vooremaa, 17. apr. 2007, lk. 2; Sõnumitooja, 18. apr. 2007, lk. 2; Lääne Elu, 18. apr. 2007, lk. 2; Valgamaalane, 19. apr. 2007, lk. 2; Virumaa Teataja, 19. apr. 2007, lk. 11; Koit, 19. apr. 2007, lk. 6; Järva Teataja, 21. apr. 2007, lk. 2; Põhjarannik, 21. apr. 2007, lk. 2; Severnoje Poberezhje, 21. apr. 2007, lk. 2. Keskkonnaminister Jaanus Tamkivi sõnul hakkab PRIA, lisaks poollooduslike koosluste toetustele, uue maaelu arengukava raames maksma Natura 2000 toetust põllumajandusmaadele ning erametsaomanikud võivad taotlema hakata saamata jäänud tulu kompenseerimist

  4. Vaktsineerimine kui hoop Eesti maaelule / Ivari Padar

    Index Scriptorium Estoniae

    Padar, Ivari, 1965-

    2001-01-01

    Põllumajandusminister selgitab põllumajandusministeeriumi tegevust Eestit ähvardava suu- ja sõrataudi tõrjumisel. Autor: Rahvaerakond Mõõdukad. Ilmunud ka: Maaleht, 12. apr. 2001, lk. 15; Nädaline, 12. apr. 2001, lk. 4; Meie Maa, 12. apr. 2001, lk. 4; Virumaa Teataja, 11. apr. 2001, lk.7; Vooremaa, 17. apr. 2001, lk. 3; Järva Teataja, 20. apr. 2001, lk. 2

  5. Euroopa Liit ja rahvahääletus / Mart Nutt

    Index Scriptorium Estoniae

    Nutt, Mart, 1962-

    2001-01-01

    Eesti riigi tuleviku seisukohalt on EL-iga ühinemise küsimuses rahva arvamuse küsimine igati õige. Rahvahääletuse ettevalmistamisest. Autor: Isamaaliit. Parlamendisaadik. Ilmunud ka: Pärnu Postimees, 3. apr. 2001, lk. 2; Võrumaa Teataja, 3. apr. 2001, lk. 2; Vooremaa, 3. apr. 2001, lk. 2; Koit, 3. apr. 2001, lk. 6; Virumaa Teataja, 6. apr. 2001, lk. 7; Sakala, 10. apr. 2001, lk. 2

  6. Sotsiaalteadlaste avalik pöördumine

    Index Scriptorium Estoniae

    2001-01-01

    Eesti ühiskond on jõudnud poliitilisse, sotsiaalsesse ja eetilisse kriisi, leiavad oma ühises pöördumises 26 sotsiaalteadlast. Ilmunud ka: Molodjozh Estonii, 23. apr. 2001, lk. 3; Estonija, 24. apr. 2001, lk. 7; Maaleht, 26. apr. 2001, lk. 9; Hiiumaa, 24. apr. 2001, lk. 2; Meie Maa, 24. apr. 2001, lk. 2; Hiiu Leht, 27. apr. 2001, lk. 2

  7. Maaleht soovitab : Akordionistid laulupeomuuseumis. Taani sõugrupp mängib Pärnus. Rahvamuusikutega pidu hommikuni. "Rock ja raga" turgutab meeli

    Index Scriptorium Estoniae

    2008-01-01

    Tartu regiooni muusikakoolide akordionistide kontserdist 12. apr. Laulupeomuuseumis Tartus (Jaama 14). Taani lõõkpillimängijate sõugrupi Trash.dk esinemisest 25. apr. Pärnu kontserdimajas. Rahvamuusikaüritusest 12. apr. Tartus roomakatoliku kirikus (Veski 1) ja Veski villas (Veski 6). Kontserdist "Rock ja raga" 11. apr. Tartus Vanemuise kontserdimajas, 12. apr. Pärnu kontserdimajas ja 13. apr. Tallinnas Estonia kontserdisaalis

  8. Uudised : Baltimaade suurim, XII "Jazzkaar". VII rahvusvaheline koorifestival. Leipzigis improviseeriti edukalt

    Index Scriptorium Estoniae

    2001-01-01

    23.-29. apr. toimuvast festivalist "Jazzkaar 2001". VII rahvusvahelisest koorifestivalist "Tallinn "2001". 6. ja 7. apr. Leipzigis toimunud V rahvusvahelisest improvisatsioonikonkursist, kus osalesid ka eesti interpreedid

  9. Vanasti oli parem / Paul-Eerik Rummo

    Index Scriptorium Estoniae

    Rummo, Paul-Eerik, 1942-

    2002-01-01

    Ilmunud ka: Hiiumaa, Koit, Lääne-Harju Ekspress, Pärnu Postimees 5. apr. lk. 2;6;3;2, Hiiu Leht 5. apr. lk. 2, Põhjarannik, Severnoje Poberezhje 5. apr. lk. 2, Vooremaa 9. apr. lk. 2, Nädaline, Valgamaalane, Lääne Elu 9. apr. lk. 2;2;4, Meie Maa 10. apr. lk. 2, Sakala 18. apr. lk. 2, Järva Teataja 20. apr. lk. 2, Paremad Uudised aprill nr. 4 lk. 7. Eesti erakonnapoliitikast. Autor: Reformierakond. Parlamendisaadik

  10. Valitsemise ilu ja valu / Mait Klaassen

    Index Scriptorium Estoniae

    Klaassen, Mait, 1955-

    2005-01-01

    Ilmunud ka: Severnoje Poberezhje 26. apr., lk. 2, Lääne Elu 26. apr., lk. 2, Vali Uudised 27. apr., lk. 2, Meie Maa 27. apr. lk. 2, Nädaline, Koit 28. apr. lk. 4,6, Türi Rahvaleht 29. apr., lk. 4, Hiiu Leht 29. apr., lk. 2, Harjumaa 29. apr. lk. 2, Valgamaalane 3. mai lk. 2, Sakala 6. mai lk. 2, Pärnu Postimees 7. mai lk. 19, Paremad Uudised mai nr. 4 lk. 7. Uue valitsuse koalitsioonileppest

  11. Kontserdipeegel : "Rüütelkonna muusika" Toompeal. Encore! Encore? / Vahur Luhtsalu

    Index Scriptorium Estoniae

    Luhtsalu, Vahur

    2001-01-01

    Kontserdiagentuuri "Concerto Grosso" barokikontsertide sarjas "Rüütelkonna muusika" toimunud kontserdist 29. apr. krahv Stackelbergi majas. TKO kontserdist 29. apr., kavas Bachi, shostakovitshi ja Haydni looming

  12. MFE与APR测试工具在高温高压井的应用对比%Applied Comparison of MFE and APR Testing Tool in HP- HT Well

    Institute of Scientific and Technical Information of China (English)

    荀忠义; 张容; 刘宏; 吴国洲

    2005-01-01

    介绍了Johnston公司的MFE和Halliburton公司的APR两种测试工具在同一口高温高压井中的应用情况.MFE测试3次全部失败,测试阀以下管柱出现漏失现象;APR使用3次均获成功.对MFE测试失败原因进行分析认为,超高压地层应用APR测试工具更为可靠.

  13. A ética como criação de qualidade de vida : o apreço pela vida como pilar de sustentação da acção humana

    OpenAIRE

    Charrua, Maria Antonieta Paixão

    2011-01-01

    Relatório da Prática de Ensino Supervisionada, Mestrado em Ensino da Filosofia, Universidade de Lisboa, 2011 O estágio realizado na Escola Manuel Cargaleiro representou um desafio extremamente importante. Esta instituição escolar, apresenta boas infra-estruturas físicas, uma equipa de docentes organizada e coerente no esforço constante de responder às necessidades da sociedade. A turma do 10º ano de escolaridade é considerada boa, os resultados quantitativos foram satisfatórios...

  14. Rhétorique de la terreur après les attentats parisiens : réflexions sur l’émergence de quelques phrasèmes

    Directory of Open Access Journals (Sweden)

    Espinat, Marine

    2016-07-01

    Full Text Available While Paris plunged 2015 into shock and mourning after two waves of terrorist attacks, media discourse was alive and well, hammering the same news on the radio, in the papers, on the radio and television. In those moments of collective stupor, the media occupy the space of public speech more than any other time. New expressions emerge and are loop relayed before getting adopted, rejected, or forgotten. The aim of this article is to analyze some of those particular expressions, notable by their vivacity in the days and weeks following the attacks. These expressions are presented from two perspectives: the first express terror and the others can be seen as the expression of togetherness. They all reflect a period both of trauma and of semantic fumbling.

  15. The climate regime before and after Copenhagen: science, policy, and the two-degrees target; Le regime climatique avant et apres Copenhague: sciences, politiques et l'objectif des deux degres

    Energy Technology Data Exchange (ETDEWEB)

    Aykut, S.C. [EHESS, Centre Alexandre Koyre, Paris (France); Dahan, A. [CNRS, Centre Alexandre Koyre, Paris (France)

    2011-04-15

    The article discusses the political results of the Copenhagen Conference and evolutions in the international climate arena including geopolitical shifts, new issues on the agenda and a changing cartography of the main actors. As recent attacks on the climate regime concern both its political governance and the peculiar relationship between science and politics that developed through its main institutions (IPCC and the Conference of the Parties), we retrace in a first part the construction of the climate arena and in a second part the framing of the problem between climate science, expertise, and politics. Drawing on this historical sketch, we suggest the years 2000 were characterized by a convergence of top-down approaches in climate expertise and policies, structuring action and discourse around quantified reduction targets, temperature and concentration thresholds, and carbon budgets. The bottom-up character of the voluntary reduction commitments in the Copenhagen Accord is a serious setback to this approach. A central figure in this context is the threshold of 'dangerous warming' of two degrees. The Copenhagen Accord - endorsed in the Cancun compromise - elevates this figure to an official target of the U.N. negotiation process, thereby accentuating the tension between a newly assumed 'Real politic' and an alarming expertise. The article analyzes the construction of the two-degrees target and the role it plays in the climate regime. We conclude by discussing several contributions to the Post-Copenhagen debate. (authors)

  16. Measurement of specific parameters for dose calculation after inhalation of aerols containing transuranium elements; Mesure de parametres specifiques pour le calcul de dose apres inhalation d'aerosols renfermant des elements transuraniens

    Energy Technology Data Exchange (ETDEWEB)

    Ramounet-le Gall, B.; Fritsch, P.; Abram, M.C.; Rateau, G.; Grillon, G.; Guillet, K. [Lab. de Radiotoxicologie, CEA/DSV/DRR/SRCA, Bruyeres le Chatel (France); Baude, S. [Lab. de Mesures Specifiques Gaz, CEA/DAM/DASE/SRCE, Bruyeres le Chatel (France); Berard, P. [Cabinet du Conseiller medical du CEA, CEA/DEN/DPS/LABM Saclay, Gif sur Yvette (France); Ansoborlo, E. [CEA/DEN/DRCP/CETAMA, Bagnols sur Ceze (France); Delforge, J. [Lab. de Radiotoxicologie, CEA/DSV/DRR/SRCA, Bruyeres le Chatel (France)

    2002-07-01

    A review on specific parameter measurements to calculate doses per unit of incorporation according to recommendations of the International Commission of Radiological Protection has been performed for inhaled actinide oxides. Alpha activity distribution of the particles can be obtained by autoradiography analysis using aerosol sampling filters at the work places. This allows us to characterize granulometric parameters of 'pure' actinide oxides, but complementary analysis by scanning electron microscopy is needed for complex aerosols. Dissolution parameters with their standard deviation are obtained after rat inhalation exposure, taking into account both mechanical lung clearance and actinide transfer to the blood estimated from bone retention. In vitro experiments suggest that the slow dissolution rate might decrease as a function of time following exposure. Dose calculation software packages have been developed to take into account granulometry and dissolution parameters as well as specific physiological parameters of exposed individuals. In the case of poorly soluble actinide oxides, granulometry and physiology appear as the main parameters controlling dose value, whereas dissolution only alters dose distribution. Validation of these software packages are in progress. (author)

  17. Influence of dose distribution on risk of lung cancer occurrence after actinide oxide inhalation; Influence de la distribution de dose sur le risque d'apparition de cancers pulmonaires apres inhalation d'oxydes d'actinides

    Energy Technology Data Exchange (ETDEWEB)

    Fritsch, P.; Dudoignon, N.; Guillet, K.; Rateau, G.; Delforge, J. [Lab. de Radiotoxicologie, CEA/DSV/DRR/SRCA, Bruyeres le Chatel (France)

    2002-07-01

    The aim of this work was to estimate risk of lung tumour occurrence after inhalation of actinide oxides from published studies and rat studies in progress. For the same delivered dose, the risk increases when homogeneity of irradiation increases, i.e., the number of particles deposited after inhalation increases (small particles and (or) low specific alpha activity). The dose-effect relationships reported appear linear up to a few gray, depending on the aerosol considered, and then the slope decreases. This slope, which corresponds with the risk, can vary over one order of magnitude de ending on the aerosol used. An effective threshold at about 1 Gy was not observed for the most homogeneous dose distributions. A dosimetric and biological approach is proposed to provide a more realistic risk estimate. (author)

  18. Therapeutic approaches of hematopoietic syndrome after serious accidental global irradiation. Ex vivo expansion interest of hematopoietic cells; Approches therapeutiques du syndrome hematopoietique apres irradiation globale accidentelle grave. Interet de l`expansion ex vivo des cellules hematopoietiques

    Energy Technology Data Exchange (ETDEWEB)

    Thierry, D.

    1994-12-31

    Aplasia is one of the main syndrome, appearing after one global accidental irradiation by one ionizing radiation source. The hematopoietic syndrome is characterized by a peripheric blood cell number fall; the cell marrow is reduced too.

  19. Définir le peuple et sa musique : les débats sur le rebetiko dans la presse de gauche pendant et après la guerre civile grecque (1946-1961)

    OpenAIRE

    Anagnostou, Panagiota

    2014-01-01

    Cet article examine les débats sur la musique populaire grecque parus dans la presse de gauche de 1946 à 1961. Au moment du conflit interne et pendant la période qui l’a suivi, les intellectuels de gauche se penchent sur les expressions du peuple en essayant d’y trouver résistance et héroïsme, d’établir la persistance des luttes et de montrer la continuité de la répression. À plusieurs reprises, la musique populaire se trouve au centre des débats et divise l’opinion. À travers l’analyse des a...

  20. Safety report concerning Melusine (after power increase to 4 MW). Descriptive part. Volumes 1 and 2; Rapport de surete de ''melusine'' (apres augmentation de puissance a 4 MW). Partie descriptive. Tomes 1 et 2

    Energy Technology Data Exchange (ETDEWEB)

    Baas, C.; Delcroix, V.; Jacquemain, M.; Marouby, R.; Meunier, C.; De Robien, E.; Rossillon, F. [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1967-03-01

    Construction of Melusine was started in January 1957, It first diverged on July 1, 1958. It operated at: 1 MW from March 1959; 1.4 MW from April 1960; 2 MW from September 1961; 4 MW from December 1965. Various modifications have been made since the reactor was built. They concern: - the addition of a hot cell. - the effluents: 2 reservoirs of 15 m{sup 3} for liquid waste have been installed. The resin regeneration equipment has been completely modified. - the building: offices have been added - experimental zones have been set up in the hall - the electrical supply. - the cooling and purification circuits (installation of a second exchanger, replacement of the primary pumps, creation of a hot layer, etc... ). - the fuel elements (at the moment of the MTR type enriched to 90 per cent). - the swimming-pool (which has been partially equipped with a stainless steel coating). - the core (placing of 'stools', of a diving-board, etc...). - the ventilation: the hall has been de-pressurized during normal working in the event of an accident, the hall can be isolated and a safety circuit can be started up. A chimney has been installed. - the hall (which has been strengthened and sealed more effectively). - the control electronics (modification of the principle, and which are now entirely transistorized). So many changes have been made that the reactor now bears only a slight resemblance to the initial model. It has appeared necessary to make a brief review of these improvements in order to be able to judge more effectively the installations present safety characteristics; these latter are furthermore fairly well known as a result of the experiments carried out not only by the Thermal Transfer Service in Grenoble but also at Cadarache (Cabri) and Toulon (the work of Mr. PASCOUET). (authors) [French] MELUSINE a ete construite a partir de janvier 1957. Sa premiere divergence a eu lieu le 1er juillet 1958. Elle a fonctionne a: 1 MW a partir de mars 1959; 1,4 MW a partir d'avril 1960; 2 MW A partir de septembre 1961; 4 MW a partir de decembre 1965. Diverses modifications ont ete apportees depuis la construction. Elles concernent: - L'adjonction d'une cellule chaude. - Les effluents: 2 cuves de 15 m{sup 3} pour effluents liquides ont ete mises en place. L'installation de regeneration des resines a ete entierement modifiee. - Le batiment: des bureaux ont ete ajoutes - des aires experimentales ont ete construites dans le hall. - L'alimentation electrique. - Les circuits de refroidissement et d'epuration (mise en place d'un second echangeur, remplacement des pompes primaires, creation d'une couche chaude, etc... ). - Les elements combustibles (actuellement elements type MTR enrichis a 90 pour cent). - La piscine (qui a ete munie partiellement d'un revetement en acier inoxydable). - Le coeur (mise en place de 'tabourets', d'un plongeoir, etc...). - La ventilation: le hall a ete mis en depression en fonctionnement normal, en cas d'incident, le hall peut etre isole et un circuit de secours peut etre demarre. Une cheminee a ete installee. - Le hall (qui a ete renforce et dont l'etancheite a ete amelioree). - L'electronique de controle (modifiee dans son principe et maintenant entierement transistorisee). L'ensemble a si profondement evolue que le reacteur n'a plus que de lointains rapports avec la realisation initiale. Il a paru necessaire de faire une breve synthese de ces ameliorations afin de mieux permettre de juger des caracteristiques de surete actuelles de l'installation, caracteristiques du reste beaucoup mieux connues du fait des experiences realisees tant a GRENOBLE au Service des Transferts Thermiques qu'a CADARACHE (Cabri) et TOULON (travaux de M. PASCOUET). (auteurs)

  1. Early functional recovery for a graft after hepatic transplantation: interest of the aminopyrine-{sup 13}C breath test; Reprise precoce de fonction du greffon apres transplantation hepatique: interet du test respiratoire a l`aminopyrine-{sup 13}C

    Energy Technology Data Exchange (ETDEWEB)

    Mion, F.; Queneau, P.E.; Boillot, O.; Minaire, Y.; Delafosse, B. [Hopital Edouard-Herriot, 69 - Lyon (France); Rousseau, M. [Inbiomed, 69 - Lyon (France); Brazier, J.L. [LEACM, 69 - Lyon (France)

    1994-12-31

    {sup 13}C-aminopyrine breath tests were carried out on 8 patients, just after liver transplantation, in order to examine the recovery of the graft metabolic functions. Test results are compared to usual data from hepatic biology and histology. Quantitative measures on hepatic functional mass are obtained. The relative sensitivity of the test could allow for detection of moderate hepatic dysfunctions. 4 figs., 8 refs.

  2. L'évolution de l'armature urbaine en Arabie du Sud: la vallée du Jawf du VIIIe siècle av. au VIe siècle apr. J.-C.

    Directory of Open Access Journals (Sweden)

    Jérémie Schiettecatte

    2006-12-01

    Full Text Available L'approche archéogéographique du peuplement de la vallée du Jawf (Yémen met ici en évidence les dynamiques qui affectent le réseau urbain de cette région au cours du Ier mill. av. J.-C. et au début de l'ère chrétienne. Cette approche permet de relativiser les causes jusqu'ici avancées du déclin et de la disparition des villes tout en mettant en avant l'impact de probables modifications environnementales et les conséquences d'une action anthropique sur le paysage plus en amont.

  3. Juste vous dire quelque chose à propos de l’infinitif. Étude de l’infinitif performatif d’après une perspective pragmatico-textuelle

    Directory of Open Access Journals (Sweden)

    Quintero Ramírez Sara

    2014-07-01

    Full Text Available La présente communication a comme objectif de définir et de caractériser les infinitifs performatifs à partir des critères pragmatico-textuels en tenant compte d’un corpus de 500 textes de différents typologies et genres. L’infinitif performatif est une construction infinitive indépendante qui n’a été étudiée ni dans les grammaires du français ni dans les monographies consacrées à l’étude de l’infinitif. Cette construction infinitive a la particularité d’être utilisée par les usagers de la langue française sans un verbe fini qui figure comme pivot de ladite construction. Au moment d’énoncer cet infinitif, l’auteur du texte utilise toujours un verbe de communication qui a la fonction de faire référence à l’acte communicatif que l’auteur réalise dans la situation d’énonciation du je, ici et maintenant. Autrement dit, l’infinitif performatif correspond à la première personne du singulier du présent de l’indicatif (Hernanz, 1999: 2341 ; Kabatek, 2008: 204. Cette correspondance n’est pas d’ordre syntaxique, mais d’ordre pragmatique et textuel. En effet, cet infinitif a une valeur performative parce que l’infinitif des verbes de communication comme dire équivaut sémantiquement à je dis grâce au cotexte et au contexte où il apparaît: a un verbe de communication qui peut être précédé ou non d’un ou de plusieurs marqueurs discursifs, b avec une fonction clairement métacommunicative, c qui s’emploi dans des textes écrits ou oraux de type factuel, expositif-explicatifs, spontanés et normalement dirigés à un public massif, d plus spécifiquement dans des genres textuels comme des blogs, des forums, des courriers des lecteurs, des débats et des discours d’accueil ou de clôture, e enfin, l’infinitif performatif est utilisé soit pour changer d’un sujet à un autre dans le texte, soit pour changer le tour de parole entre les différents interlocuteurs qui participent dans le texte.

  4. Cancer du sein: intérêt du bilan d’extension par imagerie lors du diagnostic initial et du suivi les trois premières années après le diagnostic

    OpenAIRE

    Schroeder, Hélène; Hanocq, Florence; Collignon, Joëlle; Colin, Paul-Emile; Depuis, Zoé; Triffaux, François; Rorive, Andrée; Jerusalem, Guy

    2015-01-01

    In our region, repeated tumor staging by radiological procedures aiming to detect relapses and/or metastases from breast cancer is frequently performed. However, these procedures are not recommended by current international guidelines. We retrospectively analyzed the charts from 818 patients with a new diagnosis of breast cancer seen at CHU Liege between 2005 and 2009. We assessed the role of staging procedures at initial diagnosis and during follow-up the first 3 years after the diagnosis of...

  5. La réussite scolaire dans l'enseignement professionnel en Syrie et en France, en fonction de l'orientation scolaire après la classe de troisième

    OpenAIRE

    Maarrawi, Juliette

    2013-01-01

    The two selected countries differ with respect to their Options process, and report to the criterion that takes this approach.The Options process is a choice which is an indicator (a measure) of motivation which is a central element and determiner of success at school. We study the importance of choice in the Options process, and the types of student motivation, as well as the role of motivation in academic success. Then we study the effect of the Options process on academic success and the c...

  6. Influence of melanocytes in the ex-vivo reconstructed epidermal melanin unit following an acute UV irradiation; Role des melanocytes dans l'unite epidermique de melanisation reconstruite ex-vivo apres une irradiation UV aigue

    Energy Technology Data Exchange (ETDEWEB)

    Cario-Andre, M

    2000-11-15

    Influence of melanocytes in skin pigmentation is well documented, however its photo-protective role has given rise to controversy. The role of melanocytes have been investigated on reconstructed epidermis with 100 % of keratinocytes or 95 % of keratinocytes and 5 % of melanocytes. In a first time, the effect of an acute UVB dose has been studied on both reconstructed epidermis, next we have investigated UVA and UVA+B effects on these epidermis. Following irradiation, the presence of melanocytes in reconstructed epidermis protects against apoptosis without protecting significantly against DNA damage formation (CPD, 6-4PP) and protects against UV-induced unbalance of the SOD/catalase ratio (antioxidants enzymes). On the contrary, the presence of melanocytes in reconstructed epidermis amplifies lipids and proteins oxidations but seems to protect against DNA oxidations. Melanocytes differ from keratinocytes by their melanin content and their more important concentration in polyunsaturated fatty acids. To evaluate what is the part of melanin and the part of polyunsaturated fatty acids in epidermal UV responses, reconstructed epidermis with keratinocytes have been supplemented with polyunsaturated fatty acid. This study indicates that polyunsaturated fatty acids are responsible for lipids and proteins oxidations and that melanin protect against DNA oxidation induced by lipid peroxidation. All these studies demonstrate that, model of reconstructed epidermis and epidermis in-vivo have the same behaviour following UV irradiation. In the last part, sunscreens and antioxidants have been tested on reconstructed epidermis and have demonstrated that model of reconstructed epidermis is suitable for photo-protective molecules screening. (author)

  7. Intensity-modulated radiotherapy after prostatectomy: preliminary results of a pilot study; Radiotherapie avec modulation d'intensite apres prostatectomie: resultats preliminaires d'une etude pilote

    Energy Technology Data Exchange (ETDEWEB)

    Riou, O.; Fenoglietto, P.; Azria, D.; Moscardo, C.L.; Hay, M.H.; Ailleres, N.; Dubois, J.B. [CRLC Val d' Aurelle, 34 - Montpellier (France)

    2010-10-15

    The authors discuss the results obtained on 64 patients treated by image-guided and intensity-modulated conformational irradiation (IMRT) after prostatectomy. After a while, the conventional IMRT has been replaced by a dynamic volumetric arc therapy. The treatment appeared to be feasible and well tolerated without any grade-4 severe toxicity. A longer monitoring is still necessary as far as carcinologic results and late toxicity are concerned. Short communication

  8. Après la crise financière : « réguler » ou refondre ? After the financial crisis: regulation or radical overhaul ? The shortcomings of prudential policies

    Directory of Open Access Journals (Sweden)

    Frédéric Lordon

    2009-06-01

    Full Text Available L’ampleur de la crise financière pose directement la question de l’efficacité des stratégies de régulation prudentielle telles qu’elles sont vouées à rencontrer trois écueils difficilement surmontables : 1 la puissance des forces concurrentielles qui entraînent les agents quoi qu’ils en aient ; 2 l’impossibilité essentielle du contrôle des risques ex ante ; 3 les effets symboliques de la croyance « innovation » qui distord le régime collectif des anticipations et de l’appréciation du risque. Contre les stratégies de régulation qui seront trop vraisemblablement débordées à nouveau par une dynamique de bulle, il est permis de plaider pour une refonte beaucoup plus radicale des structures de la finance selon l’objectif d’une réduction drastique de ses niveaux de profit-risque et selon le principe d’une désophistication générale de ses activités. Le présent article énonce plusieurs propositions en ce sens jusqu’à l’idée d’une modification profonde des structures bancaires qu’il s’agirait de faire évoluer dans la direction d’un « système socialisé du crédit ».The magnitude of the crisis directly questions the effectiveness of prudential regulations as they are doomed to encounter three major obstacles: 1 the competition forces as they drive agents possibly against their will; 2 the essential impossibility of a proper risk control ex ante; 3 the symbolic effects of “innovation” as a social belief as it twists collective expectations and risk appraisal. Contrary to the prudential approaches, too likely to be overwhelmed by a new bubble dynamic, the present paper advocates for a radical overhaul of financial structures, according to the twoflold principle of a drastic decrease in the profit-risk profile of capital market activities and of their severe “desophistication” as well. Several propositions are made in this line including one aiming at a new brand of banking structures giving way to what could dubbed a “socialized credit system”.

  9. Iodine 125 seed migration after prostate brachytherapy: a study of 170 patients; Migration des grains d'iode 125 apres curietherapie prostatique: etude d'une serie de 170 patients

    Energy Technology Data Exchange (ETDEWEB)

    Chauveinc, L.; Osseili, A.; Rosenwald, J.C.; Cosset, J.M. [Institut Curie, Dept. d' Oncologie-Radiotherapie, 75 - Paris (France); Flam, T. [Hopital Cochin, Service d' Urologie, 75 - Paris (France); Thiounn, N. [Hopital Necker, Service d' Urologie, 75 - Paris (France); Savignoni, A. [Institut Curie, Service de Statistiques, 75 - Paris (France)

    2004-08-01

    Purpose. To study the number of migrating seeds, the anatomical site of migration and possible predictive parameters of migration, after prostate cancer brachytherapy using a loose-seed (I125) implantation technique. Patients and methods. The charts of the 170 patients consecutively treated by the Institut Curie/Hospital Cochin/Hospital Necker Group between September 1, 2001 and August 31, 2002, were analysed. All seeds having migrated to the lungs and seen on the chest X-ray systematically performed at 2 months, have been recorded, as well as the seeds lost by the urines (after sieving) or in the sperm (condom). Results. Among 12,179 implanted seeds, 44 were found to have migrated (0.36%). Most of the migrating seeds (32/44; 73%), were found in the lungs. Overall, one or several seed migrations were observed in 35 patients (21% of the total number of patients in this series). In the majority of cases (77

  10. Varroa destructor est le principal responsable de la mort et de la réduction des populations de colonies d'abeilles (Apis mellifera) après hivernation en Ontario, Canada

    OpenAIRE

    Guzmán-Novoa, Ernesto; Eccles, Leslie; Calvete, Yireli; Mcgowan, Janine; Kelly, Paul G.; Correa-Benítez, Adriana

    2010-01-01

    International audience The relative effect of parasite levels, bee population size, and food reserves on winter mortality and post winter populations of honey bee colonies was estimated. More than 400 colonies were monitored throughout three seasons in Ontario, Canada. Most of the colonies were infested with varroa mites during the fall (75.7%), but only 27.9% and 6.1% tested positive to nosema disease and tracheal mites, respectively. Winter colony mortality was 27.2%, and when examined a...

  11. Recovery of ovarian function after postradiation menopause. Do FSH levels have a definitive prognostic value?; Recuperation de fonctionnement ovarien apres menopause radio-induite. L`hormone folliculostimulante (FSH) a-t-elle une valeur pronostique definitive?

    Energy Technology Data Exchange (ETDEWEB)

    Letur-Konirsch, H. [Hopital Necker-Enfants-Malades, 75 - Paris (France); Guis, F. [Hopital Antoine-Beclere, Clamart (France)

    1996-08-01

    Menopause, conventionally defined as the permanent cessation as a result of loss of ovarian follicular activity, is biologically expressed by the collapse of plasma levels and increased plasma levels of the gonadotrophins FSH (follicle stimulating hormone) and LH (luteinizing hormone). At present, estimation of the ovarian follicle reserve is based on endocrine capacity tests of the ovaries, with increased FSH representing the first sign of exocrine ovarian failure. We report the case of one of our amenorrhoeic patients after chemotherapy, total body radiation and allogeneic bone marrow transplantation for acute immuno-blastic leukaemia. This patient was included in an in vitro fertilization with oocyte donation (IVF-OD) programme for iatrogenic premature ovarian failure with increased FSH levels. Instead of high levels of gonadotrophins, this young woman recovered spontaneous follicular developments, benefited from standard IVF with her own oocytes and brought a twin pregnancy to term. This observation shows that a high FSH level is not a definitive prediction of ovarian exocrine capacity. In young women of child-bearing age such as these wanting a child and showing signs of endogenous estrogen impregnation, evaluation of the existence and quality of follicular development is an important factor. (author). 13 refs.

  12. Secondary mandibular fibrosarcoma after chemoradiotherapy for undifferentiated nasopharyngeal carcinoma. Report of a case and literature review; Fibrosarcome secondaire de la mandibule apres chimioradiotherapie pour carcinome indifferencie du nasopharynx. A propos d'une observation et revue de la litterature

    Energy Technology Data Exchange (ETDEWEB)

    Kochbati, L.; Besbes, M.; Benna, F.; Maalej, M. [Institut Salah Azaiz, Service de Radiotherapie, Tunis (Tunisia); Boussen, H.; Ben Ayed, F. [Institut Salah Azaiz, Service de Medecine, Tunis (Tunisia); Gritli, S.; Ladgham, A. [Institut Salah Azaiz, Service de Chirurgie ORL, Tunis (Tunisia); Saadi, A. [Institut Salah Azaiz, Service de Radiodiagnostic, Tunis (Tunisia); El May, A. [Institut Salah Azaiz, Service d' Anatomopathologie, Tunis (Tunisia)

    2001-06-01

    Secondary mandibular fibrosarcoma after chemoradiotherapy for undifferentiated nasopharyngeal carcinoma. Report of a case and literature review. Secondary tumours to radio- and/or chemotherapy have rarely been reported after treatment for head and neck cancers. We report a case of mandibular fibrosarcoma observed 7 years after chemoradiotherapy for undifferentiated nasopharyngeal carcinoma in a patient treated when 20 years old. (authors)

  13. L’Université américaine dans le débat public après le 11 septembre American Universities and the Public Debate over 9/11

    Directory of Open Access Journals (Sweden)

    Pierre Guerlain

    2009-11-01

    Full Text Available The various reactions to 9/11 in the academic community and the attacks on U.S scholars and campuses are analyzed in this article. One particular text is chosen for close scrutiny: ACTA’s “Defending Civilization: How Our Universities Are Failing America And What Can Be Done About It” The view taken here is that the atrocities of 9/11 have been instrumentalized in order to further discredit the humanities and social science departments of American universities that have been under attack at least since the so-called “culture wars”. The so-called war on terrorism threatens the civil liberties that some academics wish to preserve.

  14. Les ensembles funéraires de la Haute-Cour à Esvres-sur-Indre (37) Ier s. av. notre ère - IIe s. après J.-C.

    OpenAIRE

    Chimier, Jean-Philippe

    2009-01-01

    http://www.afeaf.org/l-association/bulletin-afeaf-1-23.htm La nécropole de la Haute Cour à Esvres-sur-Indre, utilisée durant La Tène finale et le Haut-Empire, est connue depuis la fouille d'une première série de tombes publiée en 1909. En 2008 42 nouvelles sépultures et 4 enclos ont été fouillés dans le cadre d'opérations d'archéologie préventive.

  15. Migration intra-péritonéal d'un dispositif intra utérin diagnostiqué 20 ans après l'insertion: à propos d'un cas

    Science.gov (United States)

    Bouzouba, Wail; Alaoui, Fatime Zahra Fdili; Jayi, Sofia; Bouguern, Hakima; Melhouf, Moulay Abdelilah

    2014-01-01

    Le dispositif intra-utérin (DIU) est une des méthodes contraceptives les plus efficaces et les plus utilisé à travers le monde: environ 100 millions d'utilisatrices. La perforation reste exceptionnelle âpres la pose d'un DIU cependant c'est une des complications les plus graves. Nous rapportant le cas d'une patiente de 49 ans, notion de pose de stérilet il y a 20 ans, suivie en oncologie pour un carcinome canalaire infiltrant du sein ayant bénéficiée d'un patey puis chimiothérapie adjuvante actuellement sous hormonothérapie, qui dans le cadre du bilan d'extension, un scanner thoraco-abdomino-pelvienne a objectivé la présence d'un DIU en sous hépatique. Sous guidage coelioscopique, on a réussie à retirer le DIU qui était enchâssé dans l’épiploon au niveau de la gouttière pariéto-colique droite. Nous insistons à travers cette observation et sous la lumière de la revue de la littérature sur l'efficacité et l'innocuité du DIU lorsque la technique et les indications sont rigoureusement respectées, mais aussi sur une des complications rarissime de la pose du DIU, et à mettre en évidence le rôle diagnostic et thérapeutique de la cœlioscopie dans la prise en charge de ces migrations. PMID:25184024

  16. Nécrose pariétale utérine partielle après capitonnage hémostatique au cours d'une hémorragie de la délivrance

    Science.gov (United States)

    Alaoui, Fatima Zohra Fdili; Jayi, Sofia; Bouguern, Hakima; Melhouf, Moulayabdilah; Fatemi, Hinde El; Amarti, Afaf

    2013-01-01

    L'hémorragie de la délivrance reste la première cause de mortalité dans la majorité des pays y compris le Maroc. Sa prise en charge doit être multidisciplinaire, rapide, avec mise en ‘uvre de moyens médicaux et parfois chirurgicaux pour contrôler l'hémorragie. Les techniques de compression ou de cloisonnement utérins ont été peu évaluées mais diffusées rapidement dans le monde entier vu la facilité de leur réalisation; Néanmoins des complications secondaires ont été rapportées dans la littérature dont la nécrose utérine. Nous rapportons le cas d'une patiente de 33ans césarisée à 38 semaines d'aménorrhée pour utérus cicatriciel associé à une grossesse gémellaire avec inertie utérine. Un capitonnage hémostatique a été nécessaire pour contrôler l'hémorragie, l’évolution a été marquée par la survenue d'une nécrose partielle utérine confirmée histologiquement. Nous insistons à travers cette observation et sous la lumière de la revue de la littérature sur la nécessité d'un suivi post opératoire des patientes qui bénéficient de capitonnage hémostatique pour mieux documenter l'efficacité et les complications de cet acte chirurgical qui reste encore sous évalué. PMID:24009808

  17. Management of radioactivity risk in patient's death 12 hours after Quadramet injection; Gestion du risque radioactif associe au deces d'un patient 12 heures apres injection de Quadramet

    Energy Technology Data Exchange (ETDEWEB)

    Lortal, B.; Caron, J.; Dejean, C.; Bonichon, F.; Houede, N.; Buj, S.; Cazeau, A.L. [Institut Bergonie, 33 - Bordeaux (France)

    2009-12-15

    The Bergonie Institute had faced the death of a patient treated by Quadramet, one day before. This unusual case was not yet documented in France, that's why, it led to a multidisciplinary reflection on the management of body radiating. In collaboration with the Asn and I.r.s.n., recommendations were developed and put into practice. (authors)

  18. Rectum and vesicle toxicity risk factors after prostate conformal irradiation (of 70 or 80 Gy); Facteurs de risque de toxicite rectale et vesicale apres irradiation conformationelle prostatique (de 70 ou 80 Gy)

    Energy Technology Data Exchange (ETDEWEB)

    Chira, C.; Le Prise, E.; Lahbabi, K.; Lafond, C.; Manens, J.P.; Crevoisier, R. de [Centre Eugene-Marquis, 35 - Rennes (France); Bossi, A. [Institut Gustave-Roussy, 94 - Villejuif (France); Vincendeau, S. [CHU Pontchaillou, 35 - Rennes (France); Bayat, S.; Rossille, D. [Rennes-1 Univ., Inserm U936, 35 (France)

    2009-10-15

    Purpose: Identification of delayed rectal or vesical toxicity risk factors, linked to the patients or to irradiation, in case of exclusive prostate conformal radiotherapy. conclusion: the risk of toxicity is not only increased by the high doses of irradiation ( 70 to 80 Gy) but also by average doses (40 to 50 Gy) delivered in a broad volume of organ at risk. The predictive mathematic models for the toxicity (N.T.C.P. for normal tissue complication probability) are being validated. in this series (constants adjustment). (N.C.)

  19. Substances toxiques persistantes (PTS dans les corps gras : État des lieux d’après le rapport du programme des Nations-Unies pour l’environnement (PNUE

    Directory of Open Access Journals (Sweden)

    Narbonne Jean François

    2003-07-01

    Full Text Available Depuis plus de trente ans, une attention croissante a été portée sur les risques pour la santé humaine posés par la contamination de l’environnement par les substances toxiques persistantes (PTS. Ces composés persistent pendant de longues périodes dans les compartiments abiotiques et biotiques, sont transportés sur de longues distances depuis leurs points sources et s’accumulent chez l’homme et les organismes via les chaînes alimentaires. En 1997, le PNUE propose une liste initiale de 12 substances appelées polluants organiques persistants (POPs : aldrine, endrine, dieldrine, chordane, DDT, heptachlore, toxaphène, mirex, hexachlorobenzène, PCBs, dioxines (PCDDs, furanes (PCDFs. En 2001, de nouveaux composés sont ajoutés sur la liste des PTS en fonction de leurs caractéristiques comme la liposolubilité, leur résistance à la dégradation, leur forte toxicité ou la constance des apports : hexachlorohexane, PAHs, endosulfan, pentachlorophénol, formes organiques des métaux lourds : mercure, étain et plomb, phtalates, PBDEs\\\\PBBs, chlordécone, alkyl phénols, atrazine. Les sources de PTS sont diverses : (1 Utilisation de produits chimiques industriels comme les pesticides ou les emballages, (2 Réservoirs historiques déjà présents dans l’environnement essentiellement dans les sols et les sédiments ou sous forme de stocks périmés, (3 Sous-produits de process, en particulier comme contaminants indésirables de procédés industriels et de combustion. La France a été associée au rapport de la région IV méditerranéenne. Les niveaux dans les compartiments de l’environnement sont rapportés et l’exposition de l’homme via l’alimentation (vecteur essentiel est estimée en fonction des données collectées. Une évaluation des risques associés a été faite quand les données étaient suffisantes (PAHs, PCBs, PCDD\\\\F, Me Hg. Les lipides apparaissent comme vecteurs majeurs des PTS à travers la chaîne alimentaire. Toutefois, les données sur les niveaux de contamination et leur évolution dans le temps sont souvent absentes pour certains composés et\\\\ou certaines zones comme le Sud et le Sud-Est du bassin. Une évaluation scientifique des risques associant de façon cohérente la population, les activités, les émissions, les transports et les effets dans un réseau de coopération internationale est fortement souhaitable.

  20. Aden - Mascate - Zanzibar d'après la correspondance inédite d'Émile Kuhlmann, drogman-chancelier au consulat de France à Zanzibar (1849-1856)

    OpenAIRE

    Régis Hueber

    2007-01-01

    Avant-Propos La Bibliothèque municipale de Colmar conserve, en plusieurs boîtes d'archives, les "papiers personnels" de Jean Benjamin, dit Jean Baptiste Kuhlmann, père d'Émile Kuhlmann (cote Ms 633). En l'une d'elles se trouve une importante correspondance relative au voyage et au séjour d'Émile Kuhlmann à Zanzibar (voir infra Annexe I).Ces documents sont malheureusement restés jusqu'à ce jour inconnus et, pour la plupart, encore inédits. C'est que le nom d'Émile Kuhlmann s'est effacé de la m...