WorldWideScience

Sample records for applying design principles

  1. Universal Design for Online Courses: Applying Principles to Pedagogy

    Science.gov (United States)

    Rao, Kavita; Edelen-Smith, Patricia; Wailehua, Cat-Uyen

    2015-01-01

    Universal design (UD) educational frameworks provide useful guidelines for designing accessible learning environments with the intention of supporting students with and without disabilities. This article describes how one university instructor defined and applied the principles of Universal Instructional Design (UID) to pedagogy, while designing…

  2. Accessible by Design: Applying UDL Principles in a First Year Undergraduate Course

    Science.gov (United States)

    Kumar, Kari Lynne; Wideman, Maureen

    2014-01-01

    This article presents a case study of a technology-enhanced face-to-face health sciences course in which the principles of Universal Design for Learning (UDL) were applied. Students were offered a variety of means of representation, engagement, and expression throughout the course, and were surveyed and interviewed at the end of the term to…

  3. Applying design principles to fusion reactor configurations for propulsion in space

    Science.gov (United States)

    Carpenter, Scott A.; Deveny, Marc E.; Schulze, Norman R.

    1993-01-01

    We applied three design principles (DPs) to adapt and optimize three candidate-terrestrial-fusion-reactor configurations for propulsion in space. The three design principles are: (1) provide maximum direct access to space for waste radiation, (2) operate components as passive radiators to minimize cooling-system mass, and (3) optimize the plasma fuel, fuel mix, and temperature for best specific Jet power. The three candidate-terrestrial-fusion-reactor configurations are: (1) the thermal-barrier-tandem-mirror (TBTM), (2) field-reversed-mirror (FRM), and (3) levitated-dipole-field (LDF). The resulting three candidate-space-fusion-propulsion systems have their initial-mass-to-LEO minimized and their specific jet power and reusability maximized. We performed a preliminary rating of these configurations and concluded that the leading engineering-design solution to space fusion propulsion is a modified TBTM that we call the Mirror Fusion Propulsion System.

  4. 41 CFR 102-76.55 - What sustainable development principles must Federal agencies apply to the siting, design, and...

    Science.gov (United States)

    2010-07-01

    ... and Construction Sustainable Development § 102-76.55 What sustainable development principles must... Acquisition,” Federal agencies must apply sustainable development principles to the siting, design, and... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What...

  5. Workspace Design: A case study applying participatory design principles of healthy workplaces in an industrial setting

    DEFF Research Database (Denmark)

    Broberg, Ole

    2010-01-01

    case involving the design and implementation of a new mixing technology in an industrial plant. The case showed how the WSD concept can contribute to an engineering design process. The WSD team took the role as workspace designer and by the participatory workshops achieved an impact on the technology...... project. In the role as workspace designer it was important for the WSD team to make sure that the achievements in the workshops were “transmitted” to and sustained in the ordinary engineering design process. In this case, it turned out that the artefacts such as a layout game board and documents with...

  6. Workspace Design: A case study applying participatory design principles of healthy workplaces in an industrial setting

    DEFF Research Database (Denmark)

    Broberg, Ole

    2010-01-01

    The Danish Workspace Design (WSD) research program is aimed to develop and trial a potential new concept for ergonomists and other workplace consultants who are to engage in socio-technical design processes. The objective of this paper is to report on the trial of the workspace design concept in a...... project. In the role as workspace designer it was important for the WSD team to make sure that the achievements in the workshops were “transmitted” to and sustained in the ordinary engineering design process. In this case, it turned out that the artefacts such as a layout game board and documents with...... compilations of ideas and requirements from use scenarios served as appropriate transmitter devices or inscriptions....

  7. HIGH QUALITY ENVIRONMENTAL PRINCIPLES APPLIED TO THE ARCHITECTONIC DESIGN SELECTION PROCEDURE: THE NUTRE LAB CASE

    Directory of Open Access Journals (Sweden)

    Claudia Barroso Krause

    2012-06-01

    Full Text Available The need to produce more sustainable buildings has been influencing the design decisions all over the world. That’s why it is imperative, in Brazil, the development of strategies and method to aid the decision making during the design process, focused on high quality environmental. This paper presents a decision support tool based on the principles of sustainable construction developed by the Project, Architecture and Sustainability Research Group (GPAS of Federal University of Rio de Janeiro – Brazil. The methodology has been developed for the selection of a preliminary design of a laboratory to be built at Rio Technology Park at the University campus. The support provided by GPAS occurred in three stages: the elaboration of the Reference Guide for the competitors, the development of a methodology to evaluate the proposed solutions (based on environmental performance criteria and the assistance of the members of jury in the trial phase. The theoretical framework was based upon the concepts of the bioclimatic architecture, the procedures specified by the certification HQE® (Haute Qualité Environnementale and the method suggested by the ADDENDA® architecture office. The success of this experience points out the possibility to future application in similar cases.

  8. Applying the Principles of Project Management to a Collegiate Automotive Engineering Design Project

    OpenAIRE

    Dvorkin, William Nathan

    2016-01-01

    The Hybrid Electric Vehicle Team of Virginia Tech is a collegiate automotive engineering design team that reengineers production vehicles to reduce environmental impact while maintaining vehicle marketability. The team Project Manager is responsible for coordinating high-level management and planning activities with the goal of better aligning the team with business and automotive industry practices. Project management responsibilities within the Hybrid Electric Vehicle Team are divided into ...

  9. RFID design principles

    CERN Document Server

    Lehpamer, Harvey

    2012-01-01

    This revised edition of the Artech House bestseller, RFID Design Principles, serves as an up-to-date and comprehensive introduction to the subject. The second edition features numerous updates and brand new and expanded material on emerging topics such as the medical applications of RFID and new ethical challenges in the field. This practical book offers you a detailed understanding of RFID design essentials, key applications, and important management issues. The book explores the role of RFID technology in supply chain management, intelligent building design, transportation systems, military

  10. Applying quantum principles to psychology

    International Nuclear Information System (INIS)

    This article starts out with a detailed example illustrating the utility of applying quantum probability to psychology. Then it describes several alternative mathematical methods for mapping fundamental quantum concepts (such as state preparation, measurement, state evolution) to fundamental psychological concepts (such as stimulus, response, information processing). For state preparation, we consider both pure states and densities with mixtures. For measurement, we consider projective measurements and positive operator valued measurements. The advantages and disadvantages of each method with respect to applications in psychology are discussed. (paper)

  11. Universal Instructional Design Principles for Mobile Learning

    Science.gov (United States)

    Elias, Tanya

    2011-01-01

    The report extends a previous analysis of universal instructional design principles in distance education by applying them to the design of mobile learning. Eight principles with particular relevance for distance education are selected, and their recommendations are discussed in relation to the design of educational materials for a range of mobile…

  12. Fundamental Principles of Alarm Design

    DEFF Research Database (Denmark)

    Us, Tolga; Jensen, Niels; Lind, Morten;

    2011-01-01

    Traditionally alarms are designed on the basis of empirical guidelines rather than on a sound scientific framework rooted in a theoretical foundation for process and control system design. This paper proposes scientific principles and a methodology for design of alarms based on a functional...... modeling technique (MFM) which represents a process in terms of its goals, functions and operating requirements. The reasoning capabilities of MFM enable identification of operational situations which threaten to generate an alarm and derivation of potential response scenarios. The design methodology can...... be applied to any engineering system which can be modeled by MFM. The methodology provides a set of alarms which can facilitate event interpretation and operator support for abnormal situation management. The proposed design methodology provides the information content of the alarms, but does not...

  13. Deriving and applying generally applicable safety principles

    Energy Technology Data Exchange (ETDEWEB)

    Spray, S.D.

    1998-08-01

    The nuclear detonation safety of modern nuclear weapons depends on a coordinated safety theme incorporating three general safety principles: isolation, inoperability, and incompatibility. The success of this approach has encouraged them to study whether these and/or other principles might be useful in other applications. Not surprisingly, no additional first-principles (based on physical laws) have been identified. However, a more widely applicable definition and application of the principle-based approach has been developed, resulting in a selection of strategies that are basically subsets and varied combinations of the more general principles above. However, identification of principles to be relied on is only one step in providing a safe design. As one other important example, coordinating overall architecture and strategy is essential: the authors term this a safety theme.

  14. What Metadata Principles Apply to Scientific Data?

    Science.gov (United States)

    Mayernik, M. S.

    2014-12-01

    Information researchers and professionals based in the library and information science fields often approach their work through developing and applying defined sets of principles. For example, for over 100 years, the evolution of library cataloging practice has largely been driven by debates (which are still ongoing) about the fundamental principles of cataloging and how those principles should manifest in rules for cataloging. Similarly, the development of archival research and practices over the past century has proceeded hand-in-hand with the emergence of principles of archival arrangement and description, such as maintaining the original order of records and documenting provenance. This project examines principles related to the creation of metadata for scientific data. The presentation will outline: 1) how understandings and implementations of metadata can range broadly depending on the institutional context, and 2) how metadata principles developed by the library and information science community might apply to metadata developments for scientific data. The development and formalization of such principles would contribute to the development of metadata practices and standards in a wide range of institutions, including data repositories, libraries, and research centers. Shared metadata principles would potentially be useful in streamlining data discovery and integration, and would also benefit the growing efforts to formalize data curation education.

  15. Simplified energy design economics: principles of economics applied to energy conservation and solar energy investments in buildings

    Energy Technology Data Exchange (ETDEWEB)

    Marshall, H.E.; Ruegg, R.T.

    1980-01-01

    A guide to basic economic concepts and tools for solving simple economic problems in energy conservation and for understanding complex problems is provided. The concepts of economic efficiency are discussed, followed by a discussion of the basic principles of economics required to comprehend the economic evaluations of alternative investment decisions. Step-by-step procedures for evaluating the economic desirability of alternative investments are presented to illustrate and reinforce an understanding of the principles. Five tools of economic analysis discussed are: life-cycle cost, net benefits or savings, savings-to-investment ratio, internal rate of return, and discounted payback. A solar energy system with a conventional backup system is evaluated for cost effectiveness against a conventional energy system used alone using the five tools. Factors affecting benefits and costs discussed are: discount rate, incentives, inflation, salvage value, taxes, time horizon, and uncertainty. A glossary, discount formulas and factors, and uniform present worth factors modified for energy price escalation are covered in appendices. (MCW)

  16. Universal Instructional Design Principles for Mobile Learning

    OpenAIRE

    Tanya Elias

    2011-01-01

    The report extends a previous analysis of universal instructional design principles in distance education by applying them to the design of mobile learning. Eight principles with particular relevance for distance education are selected, and their recommendations are discussed in relation to the design of educational materials for a range of mobile devices. The problems and opportunities of mobile learning are discussed as is the need for educators to focus on content design issues rather th...

  17. Applying Software Engineering Principles to Process Modeling

    OpenAIRE

    Henry, Joel

    1992-01-01

    Process models are constructed using specific modeling methods or techniques. These techniques impart certain characteristics to the models they produce. Application of the software engineering principles of information hiding, top-down functional decomposition and stepwise refinement to process modeling imparts many desirable characteristics to the process models produced. This paper describes an approach to process modeling which applies these software engineering principles to control flow...

  18. Education and training for advanced practice: Principles of course design and assessment applied to a 'stereotactic needle core biopsy of the breast' module

    International Nuclear Information System (INIS)

    In order to realise the promise of the NHS Plan, radiographers are extending their practice to encompass tasks previously undertaken by radiologists and advancing their practice by taking responsibility for clinical decision-making and autonomous membership of multidisciplinary healthcare teams. In partnership with clinical service providers Higher Education Institutes are devising programmes of study to support such professional development. This article reviews the design of a 20 credit post-graduate (M level) module in stereotactic needle core biopsy of the breast. Particular consideration is given to underpinning educational principles of course design and assessment and how these are applied in order that teaching, learning and assessment have academic rigour and clinical competence of successful students is assured

  19. Education and training for advanced practice: Principles of course design and assessment applied to a 'stereotactic needle core biopsy of the breast' module

    Energy Technology Data Exchange (ETDEWEB)

    Dixon, Anne-Marie [Division of Radiography, University of Bradford, Bradford BD5 0BB (United Kingdom)]. E-mail: a.m.dixon@bradford.ac.uk

    2006-05-15

    In order to realise the promise of the NHS Plan, radiographers are extending their practice to encompass tasks previously undertaken by radiologists and advancing their practice by taking responsibility for clinical decision-making and autonomous membership of multidisciplinary healthcare teams. In partnership with clinical service providers Higher Education Institutes are devising programmes of study to support such professional development. This article reviews the design of a 20 credit post-graduate (M level) module in stereotactic needle core biopsy of the breast. Particular consideration is given to underpinning educational principles of course design and assessment and how these are applied in order that teaching, learning and assessment have academic rigour and clinical competence of successful students is assured.

  20. Simplified energy design economics: principles of economics applied to energy conservation and solar energy investments in buildings. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Marshall, H.E.; Ruegg, R.T.; Wilson, F.

    1980-01-01

    This handbook introduces the architect and engineer to economic analysis techniques for evaluating alternative energy conservation investments in buildings. Life-cycle cost, benefit-cost, savings-to-investment, payback, and rate-of-return analyses are explained and illustrated. The procedure for discounting is described for a heat pump investment. Formulas, tables of discount factors, and detailed instructions are provided to give the reader all information required to make economic evaluations of energy conserving building designs.

  1. Simplified energy design economics: Principles of economics applied to energy conservation and solar energy investments in buildings

    Science.gov (United States)

    Marshall, H. E.; Ruegg, R. T.; Wilson, F.

    1980-01-01

    Economic analysis techniques for evaluating alternative energy conservation investments in buildings are presented. Life cycle cost, benefit cost, savings to investment, payback, and rate of return analyses are explained and illustrated. The procedure for discounting is described for a heat pump investment. Formulas, tables of discount factors, and detailed instructions are provided to give all information required to make economic evaluations of energy conserving building designs.

  2. Applying Connectivist Principles and the Task-Based Approach to the Design of a Multimodal Didactic Unit

    Directory of Open Access Journals (Sweden)

    Yeraldine Aldana Gutiérrez

    2012-12-01

    Full Text Available This article describes the pedagogical intervention developed in a public school as part of the research “Exploring Communications Practices through Facebook as a Mediatic Device”, framed within the computer mediated communications field. Twelve ninth graders’ communications practices were explored and addressed by means of multimodal technological resources and tasks based on the connectivist learning view. As a result, a didactic unit was designed in the form of the digital book Diverface. This one in turn displayed information through different media channels and semiotic elements to support its multimodal features. Teachers and students might thus need to reconstruct an alternative multimodal literacy so that they can produce and interpret texts of the same nature in online environments.

  3. Fundamental principles of alarm design

    International Nuclear Information System (INIS)

    Traditionally alarms are designed on the basis of empirical guidelines rather than on a sound scientific framework rooted in a theoretical foundation for process and control system design. This paper proposes scientific principles and a methodology for design of alarms based on a functional modeling technique (MFM) which represents a process in terms of its goals, functions and operating requirements. The reasoning capabilities of MFM enable identification of operational situations which threaten to generate an alarm and derivation of potential response scenarios. The design methodology can be applied to any engineering system which can be modeled by MFM. The methodology provides a set of alarms which can facilitate event interpretation and operator support for abnormal situation management. The proposed design methodology provides the information content of the alarms, but does not deal with alarm presentation or display design issues. A hydraulically powered grinding process is employed as an industrially relevant system to show the applicability of the proposed design methodology with promising results. (author)

  4. Principles and Criteria for Design

    DEFF Research Database (Denmark)

    Beghin, D.; Cervetto, D.; Hansen, Peter Friis

    1997-01-01

    The mandate of ISSC Committee IV.1 on principles and Criteria for Design is to report on the following:The ongoing concern for quantification of general economic and safety criteria for marine structures and for the development of appropriate principles for rational life cycle design using such...

  5. Applying bioethical principles to human biomonitoring

    Directory of Open Access Journals (Sweden)

    Harrison Myron

    2008-06-01

    Full Text Available Abstract Bioethical principles are widely used as a normative framework in areas of human research and medical care. In recent years there has been increasing formalization of their use in public health decisions. The "traditional bioethical principles" are applied in this discussion to the important issue human biomonitoring for environmental exposures. They are: (1 Autonomy – Also known as the "respect for humans" principle, people understand their own best interests; (2 Beneficence – "do good" for people; (3 Nonmaleficence – "do no harm"; (4 Justice – fair distribution of benefits and costs (including risks to health across stakeholders. Some of the points made are: (1 There is not a single generic bioethical analysis applicable to the use of human biomonitoring data, each specific use requires a separate deliberation; (2 Using unidentified, population-based biomonitoring information for risk assessment or population surveillance raises fewer bioethical concerns than personally identified biomonitoring information such as employed in health screening; (3 Companies should proactively apply normative bioethical principles when considering the disposition of products and by-products in the environment and humans; (4 There is a need for more engagement by scholars on the bioethical issues raised by the use of biomarkers of exposure; (5 Though our scientific knowledge of biology will continue to increase, there will always be a role for methods or frameworks to resolve substantive disagreements in the meaning of this data that are matters of belief rather than knowledge.

  6. Logical database design principles

    CERN Document Server

    Garmany, John; Clark, Terry

    2005-01-01

    INTRODUCTION TO LOGICAL DATABASE DESIGNUnderstanding a Database Database Architectures Relational Databases Creating the Database System Development Life Cycle (SDLC)Systems Planning: Assessment and Feasibility System Analysis: RequirementsSystem Analysis: Requirements Checklist Models Tracking and Schedules Design Modeling Functional Decomposition DiagramData Flow Diagrams Data Dictionary Logical Structures and Decision Trees System Design: LogicalSYSTEM DESIGN AND IMPLEMENTATION The ER ApproachEntities and Entity Types Attribute Domains AttributesSet-Valued AttributesWeak Entities Constraint

  7. Initial Design principles

    OpenAIRE

    Jensen, Thomas; Vatrapu, Ravi

    2015-01-01

    This paper presents a design science approach to solving persistent problems in the international shipping eco system by creating the missing common information infrastructures. Specifically, this paper reports on an ongoing dialogue between stakeholders in the shipping industry and information systems researchers engaged in the design and development of a prototype for an innovative IT-artifact called Shipping Information Pipeline which is a kind of “an internet” for shipping information. Th...

  8. Design Principles for Responsive Web

    OpenAIRE

    Aryal, Chandra Shekhar

    2014-01-01

    The purpose of this bachelor’s thesis project was to study the responsive design paradigms and development approaches for creating web pages that are optimised for adaptive web design. The additional goals were to analyse the design principles and implement prototype to find out whether it is feasible to achieve responsive design for various screen resolution of devices. The theoretical part of the thesis work explains more details of primary development approaches and design consideratio...

  9. Principles of VCSEL designing

    Science.gov (United States)

    Nakwaski, W.

    2008-03-01

    Comprehensive computer simulations are currently the most efficient and cheap methods in designing and optimisation of semiconductor device structures. Seemingly they should be as exact as possible, but in practice it is well known that the most exact approaches are also the most involved and the most time-consuming ones and need powerful computers. In some cases, cheaper somewhat simplified modelling simulations are sufficiently accurate. Therefore, an appropriate modelling approach should be chosen taking into account a compromise between our needs and our possibilities. Modelling of operation and designing of structures of vertical-cavity surface-emitting diode lasers (VCSELs) requires appropriate mathematical description of physical processes crucial for devices operation, i.e., various optical, electrical, thermal, recombination and sometimes also mechanical phenomena taking place within their volumes. Equally important are mutual interactions between above individual processes, usually strongly non-linear and creating a real network of various inter-relations. Chain is as strong as its weakest link. Analogously, model is as exact as its less exact part. Therefore it is useless to improve exactness of its more accurate parts and not to care about less exact ones. All model parts should exhibit similar accuracy. In any individual case, a reasonable compromise should be reached between high modelling fidelity and its practical convenience depending on a main modelling goal, importance and urgency of expected results, available equipment and also financial possibilities. In the present paper, some simplifications used in VCSEL modelling are discussed and their impact on exactness of VCSEL designing is analysed.

  10. Universal Instructional Design Principles for Mobile Learning

    Directory of Open Access Journals (Sweden)

    Tanya Elias

    2011-02-01

    Full Text Available The report extends a previous analysis of universal instructional design principles in distance education by applying them to the design of mobile learning. Eight principles with particular relevance for distance education are selected, and their recommendations are discussed in relation to the design of educational materials for a range of mobile devices. The problems and opportunities of mobile learning are discussed as is the need for educators to focus on content design issues rather than on searching for the next new technology.

  11. Applied Control Systems Design

    CERN Document Server

    Mahmoud, Magdi S

    2012-01-01

    Applied Control System Design examines several methods for building up systems models based on real experimental data from typical industrial processes and incorporating system identification techniques. The text takes a comparative approach to the models derived in this way judging their suitability for use in different systems and under different operational circumstances. A broad spectrum of control methods including various forms of filtering, feedback and feedforward control is applied to the models and the guidelines derived from the closed-loop responses are then composed into a concrete self-tested recipe to serve as a check-list for industrial engineers or control designers. System identification and control design are given equal weight in model derivation and testing to reflect their equality of importance in the proper design and optimization of high-performance control systems. Readers’ assimilation of the material discussed is assisted by the provision of problems and examples. Most of these e...

  12. The principles of garden design

    OpenAIRE

    Turner, Tom

    2008-01-01

    This ebook explains the 3 classic design principles: gardens should be useful, gardens should be well-made and gardens should be beautiful. They derive from Vitruvius and have influenced the design of gardens since ancient times and are as important today as they have always been.

  13. Structuring Principles for the Designer

    DEFF Research Database (Denmark)

    Miller, Thomas Dedenroth; Pedersen, Per Erik Elgård

    1998-01-01

    This paper suggests a list of structuring principles that support the designer in making alternative concepts for product architectures. Different architectures may support different points of diversification in the product life-cycle. The aim is to balance reuse of resources and reduction of...

  14. Design Principles for Hybrid Ventilation

    DEFF Research Database (Denmark)

    Heiselberg, Per

    For many years mechanical and natural ventilation systems have developed separately. Naturally, the next step in this development is the development of ventilation concepts that utilize and combine the best features from each system to create a new type of ventilation system -Hybrid Ventilation....... The hybrid ventilation concepts, design challenges and - principles are discussed and illustrated by four building examples....

  15. Principles of modern digital design

    CERN Document Server

    Lala, Parag K

    2007-01-01

    A major objective of this book is to fill the gap between traditional logic design principles and logic design/optimization techniques used in practice. Over the last two decades several techniques for computer-aided design and optimization of logic circuits have been developed. However, underlying theories of these techniques are inadequately covered or not covered at all in undergraduate text books. This book covers not only the ""classical"" material found in current text books but also selected materials that modern logic designers need to be familiar with.

  16. Teaching Spreadsheets: Curriculum Design Principles

    CERN Document Server

    Tort, Francoise

    2010-01-01

    EuSpRIG concerns direct researchers to revisit spreadsheet education, taking into account error auditing tools, checklists, and good practices. This paper aims at elaborating principles to design a spreadsheet curriculum. It mainly focuses on two important issues. Firstly, it is necessary to establish the spreadsheet invariants to be taught, especially those concerning errors and good practices. Secondly, it is important to take into account the learners' ICT experience, and to encourage them to attitudes that foster self-learning. We suggest key principles for spreadsheet teaching, and we illustrate them with teaching guidelines.

  17. Industrial instrumentation principles and design

    CERN Document Server

    Padmanabhan, Tattamangalam R

    2000-01-01

    Pneumatic, hydraulic and allied instrumentation schemes have given way to electronic schemes in recent years thanks to the rapid strides in electronics and allied areas. Principles, design and applications of such state-of-the-art instrumentation schemes form the subject matter of this book. Through representative examples, the basic building blocks of instrumentation schemes are identified and each of these building blocks discussed in terms of its design and interface characteristics. The common generic schemes synthesized with such building blocks are dealt with subsequently. This forms the scope of Part I. The focus in Part II is on application. Displacement and allied instrumentation, force and allied instrumentation and process instrumentation in terms of temperature, flow, pressure level and other common process variables are dealt with separately and exhaustively. Despite the diversity in the sensor principles and characteristics and the variety in the applications and their environments, it is possib...

  18. Design principles underlying circadian clocks.

    OpenAIRE

    Rand, D.A.; Shulgin, B. V.; D. Salazar; Millar, A. J.

    2004-01-01

    A fundamental problem for regulatory networks is to understand the relation between form and function: to uncover the underlying design principles of the network. Circadian clocks present a particularly interesting instance, as recent work has shown that they have complex structures involving multiple interconnected feedback loops with both positive and negative feedback. While several authors have speculated on the reasons for this, a convincing explanation is still lacking.We analyse both t...

  19. Applying Pedagogical Principles to CALL Courseware Development.

    Science.gov (United States)

    Wyatt, David H.

    This paper on the application of principles to computer-assisted language learning (CALL) first clarifies the the relationships between the capabilities of the computer (and computer-controlled technology) and the main approaches to second language learning. Fourteen common types of CALL programs are briefly reviewed. A "relational" classification…

  20. Design principles for precision mechanisms

    CERN Document Server

    Soemers, Herman

    2011-01-01

    The successful design of mechanisms for products, tools and equipment relies on excellent concepts and properly designed details. Both are covered in this book. Many of the examples presented have been realised in practice and properly evaluated, giving the reader/designer a high level of confidence. Every example comes with the considerations underlying the application and the limitations of the particular idea. This book is based on the work started in the 1960s by W. van der Hoek at Philips in Eindhoven, the Netherlands, and subsequently continued by M.P. Koster, culminating in the Dutch-language book “Constructieprincipes” [Design principles for accurate movement and positioning]. The core of their design approach has been preserved, while theory and examples were updated and the English language was adopted to reach a broad audience within the Netherlands as well as abroad. Herman (H.M.J.R.) Soemers is associated with the University of Twente, Enschede, the Netherlands. He also works as a technolog...

  1. Macro-environmental policy: Principles and design

    International Nuclear Information System (INIS)

    The central theme of this book is how macro-environmental policy can be developed, which does not prescribe or suggest specific technologies and products bu realizes the environmental quality desired by changing the general context. The publication is composed of four main parts. The framework for analysis and the normative principles for policy design and evaluation, the first two parts, form the analytic core. The framework for analysis gives a classification of instruments in terms of permutations of a limited number of defining elements. The normative principles guide choices in instrument design and, as the flexible response strategy, guide their application in specific policies. Detailing two main new instruments (the standard method for life cycle analysis and the substance deposit, and applying the instrument strategy as developed to the cases make up the next two parts

  2. Basic principles of applied nuclear techniques

    International Nuclear Information System (INIS)

    The technological applications of radioactive isotopes and radiation in South Africa have grown steadily since the first consignment of man-made radioisotopes reached this country in 1948. By the end of 1975 there were 412 authorised non-medical organisations (327 industries) using hundreds of sealed sources as well as their fair share of the thousands of radioisotope consignments, annually either imported or produced locally (mainly for medical purposes). Consequently, it is necessary for South African technologists to understand the principles of radioactivity in order to appreciate the industrial applications of nuclear techniques

  3. Cryostat design case studies, principles and engineering

    CERN Document Server

    2016-01-01

    This book enables the reader to learn the fundamental and applied aspects of practical cryostat design by examining previous design choices and resulting cryostat performance. Through a series of extended case studies the book presents an overview of existing cryostat design covering a wide range of cryostat types and applications, including the magnet cryostats that comprise the majority of the Large Hadron Collider at CERN, space-borne cryostats containing sensors operating below 1 K, and large cryogenic liquid storage vessels. It starts with an introductory section on the principles of cryostat design including practical data and equations. This section is followed by a series of case studies on existing cryostats, describing the specific requirements of the cryostat, the challenges involved and the design choices made along with the resulting performance of the cryostat. The cryostat examples used in the studies are chosen to cover a broad range of cryostat applications and the authors of each case are ...

  4. Redis applied design patterns

    CERN Document Server

    Chinnachamy, Arun

    2014-01-01

    This book is for developers who are already proficient in programming and capable of designing systems using traditional databases, but are new to Redis. It is assumed that you understand the basics of Redis and are familiar with the various data structures. You are also expected to be proficient in one or more programming languages through which you want to use Redis.

  5. Design principles for high current beam injection lines

    International Nuclear Information System (INIS)

    We discuss the design principles for high current injection beam lines having a high degree of beam quality preservation. These principles are applied to designing a high current e-beam injection line delivering 10 MeV e-beams from the injector to an accelerator driving LTV FELs, as proposed at CEBAF

  6. Visual Design Principles: An Empirical Study of Design Lore

    Science.gov (United States)

    Kimball, Miles A.

    2013-01-01

    Many books, designers, and design educators talk about visual design principles such as balance, contrast, and alignment, but with little consistency. This study uses empirical methods to explore the lore surrounding design principles. The study took the form of two stages: a quantitative literature review to determine what design principles are…

  7. Design principles for riboswitch function.

    Directory of Open Access Journals (Sweden)

    Chase L Beisel

    2009-04-01

    Full Text Available Scientific and technological advances that enable the tuning of integrated regulatory components to match network and system requirements are critical to reliably control the function of biological systems. RNA provides a promising building block for the construction of tunable regulatory components based on its rich regulatory capacity and our current understanding of the sequence-function relationship. One prominent example of RNA-based regulatory components is riboswitches, genetic elements that mediate ligand control of gene expression through diverse regulatory mechanisms. While characterization of natural and synthetic riboswitches has revealed that riboswitch function can be modulated through sequence alteration, no quantitative frameworks exist to investigate or guide riboswitch tuning. Here, we combined mathematical modeling and experimental approaches to investigate the relationship between riboswitch function and performance. Model results demonstrated that the competition between reversible and irreversible rate constants dictates performance for different regulatory mechanisms. We also found that practical system restrictions, such as an upper limit on ligand concentration, can significantly alter the requirements for riboswitch performance, necessitating alternative tuning strategies. Previous experimental data for natural and synthetic riboswitches as well as experiments conducted in this work support model predictions. From our results, we developed a set of general design principles for synthetic riboswitches. Our results also provide a foundation from which to investigate how natural riboswitches are tuned to meet systems-level regulatory demands.

  8. Design Principles of Open Innovation Concept – Universal Design Viewpoint

    OpenAIRE

    Mustaquim, Moyen; Nyström, Tobias

    2013-01-01

    The concept of open innovation is becoming an increasingly popular topic of interest and seems to promise a lot in organizational development. However, to date there are no certain design principles that can be followed by organizations on how to use open innovation successfully. In this paper seven design principles of open innovation concept have been proposed. The derived principles are the outcome which is based on the principles of universal design. The open innovation design, based on t...

  9. Utilizing 3D-visualization to apply compulsory ALARA principles in nuclear power plant design and day-to-day operation

    International Nuclear Information System (INIS)

    The development of an advanced visualization and simulation tool to support both design as well as day-to-day operation is presented. This tool exploits cutting edge computer graphics, physics-based effects modeling, virtual reality, and gaming technologies to establish a system that can eventually be used for the administrative planning and training of plant operators and design engineers. (authors)

  10. Game Design Principles based on Human Error

    Directory of Open Access Journals (Sweden)

    Guilherme Zaffari

    2016-03-01

    Full Text Available This paper displays the result of the authors’ research regarding to the incorporation of Human Error, through design principles, to video game design. In a general way, designers must consider Human Error factors throughout video game interface development; however, when related to its core design, adaptations are in need, since challenge is an important factor for fun and under the perspective of Human Error, challenge can be considered as a flaw in the system. The research utilized Human Error classifications, data triangulation via predictive human error analysis, and the expanded flow theory to allow the design of a set of principles in order to match the design of playful challenges with the principles of Human Error. From the results, it was possible to conclude that the application of Human Error in game design has a positive effect on player experience, allowing it to interact only with errors associated with the intended aesthetics of the game.

  11. An Analysis of the Economy Principle Applied in Cyber Language

    Institute of Scientific and Technical Information of China (English)

    肖钰敏

    2015-01-01

    With the development of network technology,cyber language,a new social dialect,is widely used in our life.The author analyzes how the economy principle is applied in cyber language from three aspects—word-formation,syntax and non-linguistic symbol.And the author collects,summarizes and analyzes the relevant language materials to prove the economy principle’s real existence in chat room and the reason why the economy principle is applied widely in cyber space.

  12. Applying the principles of augmented learning to photonics laboratory work

    Science.gov (United States)

    Fischer, U. H. P.; Haupt, Matthias; Reinboth, Christian; Just, Jens-Uwe

    2007-06-01

    Most modern communication systems are based on opto-electrical methods, wavelength division multiplex (WDM) being the most widespread. Likewise, the use of polymeric fibres (POF) as an optical transmission medium is expanding rapidly. Therefore, enabling students to understand how WDM and/or POF systems are designed and maintained is an important task of universities and vocational schools that offer education in photonics. In the current academic setting, theory is mostly being taught in the classroom, while students gain practical knowledge by performing lab experiments utilizing specialized teaching systems. In an ideal setting, students should perform such experiments with a high degree of autonomy. By applying the principles of augmented learning to photonics training, contemporary lab work can be brought closer to these ideal conditions. This paper introduces "OPTOTEACH", a new teaching system for photonics lab work, designed by Harz University and successfully released on the German market by HarzOptics. OPTOTEACH is the first POF-WDM teaching system, specifically designed to cover a multitude of lab experiments in the field of optical communication technology. It is illustrated, how this lab system is supplemented by a newly developed optical teaching software - "OPTOSOFT" - and how the combination of system and software creates a unique augmented learning environment. The paper details, how the didactic concept for the software was conceptualised and introduces the latest beta version. OPTOSOFT is specifically designed not only as an attachment to OPTOTEACH, it also allows students to rehearse various aspects of theoretical optics and experience a fully interactive and feature-rich self-learning environment. The paper further details the first experiences educators at Harz University have made working with the lab system as well as the teaching software. So far, the augmented learning concept was received mostly positive, although there is some potential

  13. Team learning center design principles

    Energy Technology Data Exchange (ETDEWEB)

    Daily, B.; Loveland, J.; Whatley, A. [New Mexico State Univ., Las Cruces, NM (United States)] [and others

    1995-06-01

    This is a preliminary report of a multi-year collaboration of the authors addressing the subject: Can a facility be designed for team learning and would it improve the efficiency and effectiveness of team interactions? Team learning in this context is a broad definition that covers all activities where small to large groups of people come together to work, to learn, and to share through team activities. Multimedia, networking, such as World Wide Web and other tools, are greatly enhancing the capability of individual learning. This paper addresses the application of technology and design to facilitate group or team learning. Many organizational meetings need tens of people to come together to do work as a large group and then divide into smaller subgroups of five to ten to work and then to return and report and interact with the larger group. Current facilities were not, in general, designed for this type of meeting. Problems with current facilities are defined and a preliminary design solution to many of the identified problems is presented.

  14. Principles for Effective Hypermedia Design.

    Science.gov (United States)

    Brooks, Randy M.

    1993-01-01

    Argues that effective hypermedia designs should meet four goals: (1) minimize clutter so that the document looks and feels simple to use; (2) create an image appropriate to the corporate sponsor and to the users' expectations; (3) provide ready access to stored information; (4) minimize the effort, technology, and resources needed. (SR)

  15. Game Design Principles based on Human Error

    OpenAIRE

    Guilherme Zaffari; André Luiz Battaiola

    2016-01-01

    This paper displays the result of the authors’ research regarding to the incorporation of Human Error, through design principles, to video game design. In a general way, designers must consider Human Error factors throughout video game interface development; however, when related to its core design, adaptations are in need, since challenge is an important factor for fun and under the perspective of Human Error, challenge can be considered as a flaw in the system. The research u...

  16. Design Principles for Augmented Reality Learning

    Science.gov (United States)

    Dunleavy, Matt

    2014-01-01

    Augmented reality is an emerging technology that utilizes mobile, context-aware devices (e.g., smartphones, tablets) that enable participants to interact with digital information embedded within the physical environment. This overview of design principles focuses on specific strategies that instructional designers can use to develop AR learning…

  17. Design Communication: Transfer of Design Principles & Practice

    OpenAIRE

    Guille, Jackie

    2011-01-01

    The report documents a consultancy undertaken for Traidcraft, UK focused on one of their long-standing suppliers St. Mary's Mahila Shikshan Kendra (SMSK), Ahmedabad in the provision of training in design innovation, to both consolidate and sustain their existing creative practice in embroidered products and to support and facilitate the progressive development of design expertise at SMSK. Traidcraft is the UK’s leading Fairtrade organisation and has had a valued relationship with SMSK that st...

  18. Principles of study design in environmental epidemiology.

    OpenAIRE

    Morgenstern, H; Thomas, D.

    1993-01-01

    This paper discusses the principles of study design and related methodologic issues in environmental epidemiology. Emphasis is given to studies aimed at evaluating causal hypotheses regarding exposures to suspected health hazards. Following background sections on the quantitative objectives and methods of population-based research, we present the major types of observational designs used in environmental epidemiology: first, the three basic designs involving the individual as the unit of anal...

  19. Design Principles for Synthesizable Processor Cores

    DEFF Research Database (Denmark)

    Schleuniger, Pascal; McKee, Sally A.; Karlsson, Sven

    2012-01-01

    As FPGAs get more competitive, synthesizable processor cores become an attractive choice for embedded computing. Currently popular commercial processor cores do not fully exploit current FPGA architectures. In this paper, we propose general design principles to increase instruction throughput on...... FPGA-based processor cores: first, superpipelining enables higher-frequency system clocks, and second, predicated instructions circumvent costly pipeline stalls due to branches. To evaluate their effects, we develop Tinuso, a processor architecture optimized for FPGA implementation. We demonstrate...... through the use of micro-benchmarks that our principles guide the design of a processor core that improves performance by an average of 38% over a similar Xilinx MicroBlaze configuration....

  20. Applying Critical Scandinavian ISD research principles in an African Context

    DEFF Research Database (Denmark)

    Mengiste, Shegaw Anagaw; Tjørnehøj, Gitte

    2013-01-01

    IT-driven organizational changes through information systems development and implementation (ISD&I) is highly challenging because of high complexity and many stakeholders and even more so in developing countries, where the failure rates are higher than elsewhere. Unfortunately, since...... these countries have a vast need for the technology to develop their economies and living standards. We investigate opportunities of applying Scandinavian principles for ISD&I in the context of Africa, through analyzing and comparing two action research projects that have applied two classic approaches; The Trade...

  1. Design Principles for Natural and Hybrid Ventilation

    DEFF Research Database (Denmark)

    Heiselberg, Per

    For many years mechanical and natural ventilation systems have developed separately. Naturally, the next step in this development is the development of ventilation concepts that utilize and combine the best features from each system to create a new type of ventilation system- Hybrid Ventilation....... The hybrid ventilation concepts, design challenges and principles are discussed and illustrated by four building examples....

  2. Teaching geometrical principles to design students

    Directory of Open Access Journals (Sweden)

    Christoph Bartneck

    2009-12-01

    Full Text Available We propose a new method of teaching the principles of geometry to design students. The students focus on a field of design in which geometry is the design: tessellation. We review different approaches to geometry and the field of tessellation before we discuss the setup of the course. Instead of employing 2D drawing tools, such as Adobe Illustrator, the students define their tessellation in mathematical formulas, using the Mathematica software. This procedure enables them to understand the mathematical principles on which graphical tools, such as Illustrator are built upon. But we do not stop at a digital representation of their tessellation design we continue to cut their tessellations in Perspex. It moves the abstract concepts of math into the real world, so that the students can experience them directly, which provides a tremendous reward to the students.

  3. System analysis, design, and development concepts, principles, and practices

    CERN Document Server

    Wasson, Charles S

    2006-01-01

    Written in a practical, easy to understand style, this text provides a step-by-step guide to System Analysis and Engineering by introducing concepts, principles, and practices via a progression of topical, lesson oriented chapters.Each chapter focuses on specific aspects of system analysis, design, and development, and includes definitions of key terms, examples, author''s notes, key principles, and challenging exercises that teach readers to apply their knowledge to real world systems.Concepts and methodologies presented can be applied by organizations in business sectors such as transportati

  4. A Protocol for Evaluating Contextual Design Principles

    Directory of Open Access Journals (Sweden)

    Arthur Stamps

    2014-11-01

    Full Text Available This paper explains how scientific data can be incorporated into urban design decisions, such as evaluating contextual design principles. The recommended protocols are based on the Cochrane Reviews that have been widely used in medical research. The major concepts of a Cochrane Review are explained, as well as the underlying mathematics. The underlying math is meta-analysis. Data are reported for three applications and seven contextual design policies. It is suggested that use of the Cochrane protocols will be of great assistance to planners by providing scientific data that can be used to evaluate the efficacies of contextual design policies prior to implementing those policies.

  5. Designing for Success: Developing Engineers Who Consider Universal Design Principles

    Science.gov (United States)

    Bigelow, Kimberly Edginton

    2012-01-01

    Engineers must design for a diverse group of potential users of their products; however, engineering curricula rarely include an emphasis on universal design principles. This research article details the effectiveness of a design project implemented in a first-year engineering course in an effort to raise awareness of the need for engineers to be…

  6. Principles and techniques for designing precision machines

    Energy Technology Data Exchange (ETDEWEB)

    Hale, L C

    1999-02-01

    This thesis is written to advance the reader's knowledge of precision-engineering principles and their application to designing machines that achieve both sufficient precision and minimum cost. It provides the concepts and tools necessary for the engineer to create new precision machine designs. Four case studies demonstrate the principles and showcase approaches and solutions to specific problems that generally have wider applications. These come from projects at the Lawrence Livermore National Laboratory in which the author participated: the Large Optics Diamond Turning Machine, Accuracy Enhancement of High- Productivity Machine Tools, the National Ignition Facility, and Extreme Ultraviolet Lithography. Although broad in scope, the topics go into sufficient depth to be useful to practicing precision engineers and often fulfill more academic ambitions. The thesis begins with a chapter that presents significant principles and fundamental knowledge from the Precision Engineering literature. Following this is a chapter that presents engineering design techniques that are general and not specific to precision machines. All subsequent chapters cover specific aspects of precision machine design. The first of these is Structural Design, guidelines and analysis techniques for achieving independently stiff machine structures. The next chapter addresses dynamic stiffness by presenting several techniques for Deterministic Damping, damping designs that can be analyzed and optimized with predictive results. Several chapters present a main thrust of the thesis, Exact-Constraint Design. A main contribution is a generalized modeling approach developed through the course of creating several unique designs. The final chapter is the primary case study of the thesis, the Conceptual Design of a Horizontal Machining Center.

  7. Intelligent computer systems in engineering design principles and applications

    CERN Document Server

    Sunnersjo, Staffan

    2016-01-01

    This introductory book discusses how to plan and build useful, reliable, maintainable and cost efficient computer systems for automated engineering design. The book takes a user perspective and seeks to bridge the gap between texts on principles of computer science and the user manuals for commercial design automation software. The approach taken is top-down, following the path from definition of the design task and clarification of the relevant design knowledge to the development of an operational system well adapted for its purpose. This introductory text for the practicing engineer working in industry covers most vital aspects of planning such a system. Experiences from applications of automated design systems in practice are reviewed based on a large number of real, industrial cases. The principles behind the most popular methods in design automation are presented with sufficient rigour to give the user confidence in applying them on real industrial problems. This book is also suited for a half semester c...

  8. Principles of study design in environmental epidemiology.

    Science.gov (United States)

    Morgenstern, H; Thomas, D

    1993-01-01

    This paper discusses the principles of study design and related methodologic issues in environmental epidemiology. Emphasis is given to studies aimed at evaluating causal hypotheses regarding exposures to suspected health hazards. Following background sections on the quantitative objectives and methods of population-based research, we present the major types of observational designs used in environmental epidemiology: first, the three basic designs involving the individual as the unit of analysis (i.e., cohort, cross-sectional, and case-control studies) and a brief discussion of genetic studies for assessing gene-environment interactions; second, various ecologic designs involving the group or region as the unit of analysis. Ecologic designs are given special emphasis in this paper because of our lack of resources or inability to accurately measure environmental exposures in large numbers of individuals. The paper concludes with a section highlighting current design issues in environmental epidemiology and several recommendations for future work. PMID:8206038

  9. Universal Instructional Design Principles for Moodle

    Directory of Open Access Journals (Sweden)

    Tanya Elias

    2010-05-01

    Full Text Available The paper identifies a set of universal instructional design (UID principles appropriate to distance education (DE and tailored to the needs of instructional designers and instructors teaching online. These principles are then used to assess the accessibility level of a sample online course and the availability of options in its LMS platform (Moodle to increase course accessibility. Numerous accessibility-sensitive plug-in modules are found to be available to Moodle users, though relatively few features were included in the sample course analysed. This may be because they have not been made available to instructors at the institutional level. The paper offers a series of recommendations to improve the accessibility of online DE to learners with diverse abilities, disabilities, and needs.

  10. Implantable biomedical microsystems design principles and applications

    CERN Document Server

    Bhunia, Swarup; Sawan, Mohamad

    2015-01-01

    Research and innovation in areas such as circuits, microsystems, packaging, biocompatibility, miniaturization, power supplies, remote control, reliability, and lifespan are leading to a rapid increase in the range of devices and corresponding applications in the field of wearable and implantable biomedical microsystems, which are used for monitoring, diagnosing, and controlling the health conditions of the human body. This book provides comprehensive coverage of the fundamental design principles and validation for implantable microsystems, as well as several major application areas. Each co

  11. Y-12 Sustainable Design Principles for Building Design and Construction

    Energy Technology Data Exchange (ETDEWEB)

    Jackson, J. G.

    2008-11-01

    B&W Y-12 is committed to modernizing the Y-12 complex to meet future needs with a sustainable and responsive infrastructure and to integrating sustainability principles and practices into Y-12 work (Y72-001, B&W Y-12 Environmental, Safety and Health Policy). This commitment to sustainability and specifically sustainable design of buildings is also incorporated into Presidential Executive Orders (EO), DOE Orders (DOE O), and goals. Sustainable building design is an approach to design, construct, and operate facilities in an efficient and environmentally sound manner that will produce a healthful, resource-efficient and productive working environment that is inherently protective of the environment. The DOE has established the following 5 Guiding Principles for High Performance Sustainable Building (HPSB), and has issued directives that require Y-12 to incorporate the principles and a number of supporting specific practices and techniques into building design, construction and renovation projects: (1) Employ Integrated Design Principles; (2) Optimize Energy Performance; (3) Protect and Conserve Water; (4) Enhance Indoor Environmental Quality; and (5) Reduce Environmental Impact of Materials. The purpose of this document is to present the required sustainable building principles, practices and techniques, summarize the key drivers for incorporating them into Y-12 projects, and present additional recommendations and resources that can be used to support sustainable buildings to enhance the environmental and economic performance of the Y-12 Complex.

  12. Apply Design Patterns to Refactor Software Design

    Science.gov (United States)

    Baggs, Rhoda; Shaykhian, Gholam Ali

    2007-01-01

    Refactoring software design is a method of changing software design while explicitly preserving its unique design functionalities. Presented approach is to utilize design patterns as the basis for refactoring software design. Comparison of a design solution will be made through C++ programming language examples to exploit this approach. Developing reusable component will be discussed, the paper presents that the construction of such components can diminish the added burden of both refactoring and the use of design patterns.

  13. Do flow principles of operations management apply to computing centres?

    CERN Document Server

    Abaunza, Felipe; Hameri, Ari-Pekka; Niemi, Tapio

    2014-01-01

    By analysing large data-sets on jobs processed in major computing centres, we study how operations management principles apply to these modern day processing plants. We show that Little’s Law on long-term performance averages holds to computing centres, i.e. work-in-progress equals throughput rate multiplied by process lead time. Contrary to traditional manufacturing principles, the law of variation does not hold to computing centres, as the more variation in job lead times the better the throughput and utilisation of the system. We also show that as the utilisation of the system increases lead times and work-in-progress increase, which complies with traditional manufacturing. In comparison with current computing centre operations these results imply that better allocation of jobs could increase throughput and utilisation, while less computing resources are needed, thus increasing the overall efficiency of the centre. From a theoretical point of view, in a system with close to zero set-up times, as in the c...

  14. Design principles for therapeutic angiogenic materials

    Science.gov (United States)

    Briquez, Priscilla S.; Clegg, Lindsay E.; Martino, Mikaël M.; Gabhann, Feilim Mac; Hubbell, Jeffrey A.

    2016-01-01

    Despite extensive research, pro-angiogenic drugs have failed to translate clinically, and therapeutic angiogenesis, which has potential in the treatment of various cardiovascular diseases, remains a major challenge. Physiologically, angiogenesis — the process of blood-vessel growth from existing vasculature — is regulated by a complex interplay of biophysical and biochemical cues from the extracellular matrix (ECM), angiogenic factors and multiple cell types. The ECM can be regarded as the natural 3D material that regulates angiogenesis. Here, we leverage knowledge of ECM properties to derive design rules for engineering pro-angiogenic materials. We propose that pro-angiogenic materials should be biomimetic, incorporate angiogenic factors and mimic cooperative interactions between growth factors and the ECM. We highlight examples of material designs that demonstrate these principles and considerations for designing better angiogenic materials.

  15. Design principle of the peripheral vision display system

    Science.gov (United States)

    Guo, Xiaowei; Wang, Yuefeng; Niu, Yanxiong; Yu, Lishen; Liu, Shen H.

    1996-09-01

    The peripheral vision display system (PVDS) presents the pilot with a gyro stabilized artificial horizon projected onto the instrument panel by means of a red laser light source. The pilot can detect changes to aircraft attitude without continuously referring back to his flight instruments. The PVDS effectively applies the peripheral vision of the pilot to overcome disorientation. This paper gives the principles of the PVDS, according to which, we have designed the PVDS and used it for aviation medicine.

  16. Existential Design Applied in Universal Design Settings.

    Science.gov (United States)

    Torkildsby, Anne Britt

    2016-01-01

    The critical design method aims to discuss ways of opening up the (design) brief when planning, designing, building, operating and maintaining the future of the built environment - public as well as private, indoor as well as outdoor. Focusing on "designials" (fundamental forms of design being), the methodology intends to illustrate the fact that objects; including buildings, parks, transportation systems, etc. may directly encroach upon certain "existentials" (fundamental forms of human being) - thus shed light on how a design process is normally conducted, and furthermore, how that affects people's existential well-being. PMID:27534284

  17. Applying Software Design Methodology to Instructional Design

    Science.gov (United States)

    East, J. Philip

    2004-01-01

    The premise of this paper is that computer science has much to offer the endeavor of instructional improvement. Software design processes employed in computer science for developing software can be used for planning instruction and should improve instruction in much the same manner that design processes appear to have improved software. Techniques…

  18. Applied optics and optical design

    CERN Document Server

    Conrady, A E

    2011-01-01

    ""For the optical engineer it is an indispensable work."" - Journal, Optical Society of America""As a practical guide this book has no rival."" - Transactions, Optical Society""A noteworthy contribution,"" - Nature (London)Part I covers all ordinary ray-tracing methods, together with the complete theory of primary aberrations and as much of higher aberration as is needed for the design of telescopes, low-power microscopes and simple optical systems. Chapters: Fundamental Equations, Spherical Aberration, Physical Aspect of Optical Images, Chromatic Aberration, Design of Achromatic Object-Glass

  19. Applying persuasive design in a diabetes mellitus application

    OpenAIRE

    Smink, Sjoerd

    2012-01-01

    This paper describes persuasive design methods and compares this to an application currently under development for diabetes mellitus patients. Various elements of persuasion and a categorization of persuasion types are mentioned. Also discussed are principles of how successful persuasion should be designed, as well as the practical applications and ethics of persuasive design. This paper is not striving for completeness of theories on the topic, but uses the theories to compare it to an appli...

  20. Applying Craniofacial Principles to Neurosurgical Exposures in Cerebrovascular Aneurysm Repair.

    Science.gov (United States)

    Alperovich, Michael; Frey, Jordan D; Potts, Matthew B; Riina, Howard A; Staffenberg, David A

    2016-06-01

    The subspecialty of craniofacial surgery emphasizes skeletal exposure, preservation of critical structures, and provision of a superior cosmetic result. In recent decades, an emphasis on minimally invasive neurosurgical exposure has paved the way for increased collaboration between neurosurgeons and craniofacial surgeons.The 1990s saw the growing popularity of an eyebrow incision for orbital roof craniotomies in neurosurgery to address lesions in the anterior skull base. Disadvantages of this approach included conspicuous scarring above the brow skin, risk of injury to the frontal branch of the facial nerve, and numbness from supraorbital or supratrochlear nerve transection.A transpalpebral approach was first described in 2008 in the neurosurgical literature. An approach familiar to the craniofacial surgeon, transpalpebral exposure is used for zygomaticomaxillary complex fractures as well as aesthetic brow and periorbital surgery.In conjunction with neurosurgery, the authors have applied craniofacial principles to address the major pitfalls of the transpalpebral craniotomy. The authors present their patient series experience. Hopefully, in the future, other institutions will have increased collaboration between craniofacial surgeons and neurosurgeons. PMID:27192638

  1. Design principles of shift current photovoltaics

    Science.gov (United States)

    Cook, Ashley; Fregoso, Benjamin; de Juan, Fernando; Moore, Joel

    While the basic principles and limitations of conventional solar cells are well understood, relatively little attention has gone toward evaluating and maximizing the potential efficiency of photovoltaic devices based on shift currents. In this work, a sum rule approach is introduced and used to outline design principles for optimizing shift currents for photon energies near the band gap, which depend on wavefunctions via Berry connections as well as standard band structure. Using these we identify two new classes of shift current photovoltaics, ferroelectric polymer films and orthorhombic monochalcogenides, both of which exhibit peak photoresponsivities larger than predictions for previously-known photovoltaics of this type. Using physically-motivated tight-binding models, the full frequency dependent response of these materials is obtained. Exploring the phase space of these models, we find photoresponsivities that can exceed 100 mA/W. These results show that considering the microscopic origin of shift current via effective models allows one to improve the possible efficiency of devices using this mechanism and better grasp their potential to compete with conventional solar cells. This work was completed with the support of an NSERC Michael Smith Foreign Study Supplement.

  2. The Extent of Jordanian Banks Commitment in Applying the Principles of Corporate Governance

    OpenAIRE

    Eman Al hanini

    2014-01-01

    This study aimed to reveal the extent of Jordanian banks? commitment to apply the principles of corporate governance. And to achieve this objective , a questionnaire was designed and distributed to a sample consisted of 120 respondents of the general managers? assistants, managers of the administrations , managers of the branches, the assistants of the managers of the branches and the employees of the audit departments in the Jordanian banks. After data was analyzed using SPSS, the study conc...

  3. Applying the Legal Security Principle in Administrative Law

    Directory of Open Access Journals (Sweden)

    Vasilica NEGRUŢ

    2015-08-01

    Full Text Available The objective of the paper is founded on a very current topic and of real interest. Using content analysis, through a descriptive study research, this study aims at identifying the content of the legal security principle and the way in which the courts in Romania, the public authorities achieve a proper application of this European principle. For this purpose, it was achieved an analysis of specific objectives aiming at, in particular, the requirements of legal security principle and the way in which they manifest in the national law. We appreciate that, although it does not beneficiate of an express assignment in the Romanian legislation, being a creation of jurisprudence, the legal security principle is in the current context, a fundamental principle of state law, which should give every citizen the opportunity to evolve into a secured, predictable legal environment.

  4. Representing Clarity: Using Universal Design Principles to Create Effective Hybrid Course Learning Materials

    Science.gov (United States)

    Spiegel, Cheri Lemieux

    2012-01-01

    This article describes how the author applied principles of universal design to hybrid course materials to increase student understanding and, ultimately, success. Pulling the three principles of universal design--consistency, color, and icon representation--into the author's Blackboard course allowed her to change the types of reading skills…

  5. 12 CFR 223.21 - What valuation and timing principles apply to credit transactions?

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false What valuation and timing principles apply to...) Valuation and Timing Principles Under Section 23A § 223.21 What valuation and timing principles apply to credit transactions? (a) Valuation—(1) Initial valuation. Except as provided in paragraph (a)(2) or...

  6. 12 CFR 223.22 - What valuation and timing principles apply to asset purchases?

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false What valuation and timing principles apply to...) Valuation and Timing Principles Under Section 23A § 223.22 What valuation and timing principles apply to asset purchases? (a) Valuation—(1) In general. Except as provided in paragraph (a)(2) of this section,...

  7. Four Principles Fundamental to Design Practice for Human Centred Systems

    OpenAIRE

    Hinze-Hoare, Vita

    2004-01-01

    A Survey of the principal literature on Human Centred Design reveals the four most referenced principles. These are discussed with reference to the application of a particular website, and a user survey is constructed based upon the four principles.

  8. Fuel cells principles, design, and analysis

    CERN Document Server

    Revankar, Shripad T

    2014-01-01

    ""This book covers all essential themes of fuel cells ranging from fundamentals to applications. It includes key advanced topics important for understanding correctly the underlying multi-science phenomena of fuel cell processes. The book does not only cope with traditional fuel cells but also discusses the future concepts of fuel cells. The book is rich on examples and solutions important for applying the theory into practical use.""-Peter Lund, Aalto University, Helsinki""A good introduction to the range of disciplines needed to design, build and test fuel cells.""-Nigel Brandon, Imperial Co

  9. USE OF MORPHOLOGICAL TRANSFORMATION PRINCIPLES IN THE DESIGN OF GARMENTS BY CONFORMANCE TYPES

    OpenAIRE

    Irina Tutunaru; Marcela Irovan; Stela Balan; Natalia Leșan

    2013-01-01

    The work considers the problem of personalized design of garments for various groups of wearers and presents the results of theoretical and experimental research of garments for women elaborated in correlation with the particularities of conformance types by applying the principles of designing products with flexible structure.The analysis of concept of design of products with flexible structure and the determination of design principles contributed to the grounded selection of model system p...

  10. Toward instructional design principles: Inducing Faraday's law with contrasting cases

    Science.gov (United States)

    Kuo, Eric; Wieman, Carl E.

    2016-06-01

    Although physics education research (PER) has improved instructional practices, there are not agreed upon principles for designing effective instructional materials. Here, we illustrate how close comparison of instructional materials could support the development of such principles. Specifically, in discussion sections of a large, introductory physics course, a pair of studies compare two instructional strategies for teaching a physics concept: having students (i) explain a set of contrasting cases or (ii) apply and build on previously learned concepts. We compare these strategies for the teaching of Faraday's law, showing that explaining a set of related contrasting cases not only improves student performance on Faraday's law questions over building on a previously learned concept (i.e., Lorentz force), but also prepares students to better learn subsequent topics, such as Lenz's law. These differences persist to the final exam. We argue that early exposure to contrasting cases better focuses student attention on a key feature related to both concepts: change in magnetic flux. Importantly, the benefits of contrasting cases for both learning and enjoyment are enhanced for students who did not first attend a Faraday's law lecture, consistent with previous research suggesting that being told a solution can circumvent the benefits of its discovery. These studies illustrate an experimental approach for understanding how the structure of activities affects learning and performance outcomes, a first step toward design principles for effective instructional materials.

  11. Principles of human joint replacement design and clinical application

    CERN Document Server

    Buechel, Frederick F

    2015-01-01

    This book is written for the users and designers of joint replacements. In its second extended edition it conveys to the reader the knowledge accumulated by the authors during their forty year effort on the development of replacement devices for the lower limb for the purpose of aiding the reader in their design and evaluation of joint replacement devices. The early chapters describe the engineering, scientific and medical principles needed for replacement joint evaluation. One must understand the nature and performance of the materials involved and their characteristics in vivo, i.e. the response of the body to implant materials. It is also essential to understand the response of the implants to applied loading and motion, particularly in the hostile physiological environment. A chapter describes the design methodology now required for joint replacement in the USA and EU countries. The remaining chapters provide a history of joint replacement, an evaluation of earlier and current devices and sample case hist...

  12. Principles of Human Joint Replacement Design and Clinical Application

    CERN Document Server

    Buechel, Frederick F

    2012-01-01

    Drs. Buechel, an orthopaedic surgeon, and Pappas, a professor of Mechanical Engineering, are the designers of several successful joint replacement systems. The most well-known of these is the pioneering LCS knee replacement. They have written this book for the users and designers of joint replacements. It is an attempt to convey to the reader the knowledge accumulated by the authors during their thirty five year effort on the development of replacement devices for the lower limb for the purpose of aiding the reader in their design and evaluation of joint replacement devices. The early chapters describe the engineering, scientific and medical principles needed for replacement joint evaluation. One must understand the nature and performance of the materials involved and their characteristics in vivo, i.e. the response of the body to implant materials. It is also essential to understand the response of the implants to applied loading and motion, particularly in the hostile physiological environment. A chapter de...

  13. An Approach to Representation for Principle Scheme Design

    Institute of Scientific and Technical Information of China (English)

    ZhangJianming; WeiXiaoPeng; 等

    2002-01-01

    One of the open issues in principle scheme design of mechanical systems is principle representation,which not only outlies the physical principles,but also facilitates the design synthesis.An energy-based approach to represent principle scheme design is proposed.Firstly,an energy interaction model of mechanical systems is established and an intermediate model is derived,in which principle scheme design is transformed into solving the energy functions of system.Then the energy functions are modeled with the language of bond graphs,and principle representation for componenyts is presented.Finally,characteristics of the developed representation approach are analyzed and a design example of gate drive system is given to demonstrate this approach.

  14. Lean principles applied to software development – avoiding waste

    Directory of Open Access Journals (Sweden)

    Ionel NAFTANAILA

    2009-12-01

    Full Text Available Under the current economic conditions many organizations strive to continue the trend towards adopting better software development processes, in order to take advantage of the numerous benefits that these can offer. Those benefits include quicker return on investment, better software quality, and higher customer satisfaction. To date, however, there is little body of research that can guide organizations in adopting modern software development practices, especially when it comes to Lean thinking and principles. To address this situation, the current paper identifies and structures the main wastes (or muda in Lean terms in software development as described by Lean principles, in an attempt to bring into researchers’ and practitioners’ attention Lean Software Development, a modern development methodology based on well-established practices such as Lean Manufacturing or Toyota Production System.

  15. General design safety principles for nuclear power plants

    International Nuclear Information System (INIS)

    This Safety Guide provides the safety principles and the approach that have been used to implement the Code in the Safety Guides. These safety principles and the approach are tied closely to the safety analyses needed to assist the design process, and are used to verify the adequacy of nuclear power plant designs. This Guide also provides a framework for the use of other design Safety Guides. However, although it explains the principles on which the other Safety Guides are based, the requirements for specific applications of these principles are mostly found in the other Guides

  16. The Cheshire Cat principle applied to hybrid bag models

    International Nuclear Information System (INIS)

    Here is argued for the Cheshire Cat point of view according to which the bag (itself) has only notational, but no physical significance. It is explained in a 1+1 dimensional exact Cheshire Cat model how a fermion can escape from the bag by means of an anomaly. We also suggest that suitably constructed hybrid bag models may be used to fix such parameters of effective Lagrangians that can otherwise be obtained from experiments only. This idea is illustrated in a calculation of the mass of the pseudoscalar η' meson in 1+1 dimension. Thus there is hope to find a construction principle for a phenomenologically sensible model. (orig.)

  17. Transformer design principles with applications to core-form power transformers

    CERN Document Server

    Del Vecchio, Robert M

    2010-01-01

    Updating and reorganizing the valuable information in the first edition to enhance logical development, Transformer Design Principles: With Applications to Core-Form Power Transformers, Second Edition remains focused on the basic physical concepts behind transformer design and operation. Starting with first principles, this book develops the reader's understanding of the rationale behind design practices by illustrating how basic formulae and modeling procedures are derived and used. Simplifies presentation and emphasizes fundamentals, making it easy to apply presented results to your own desi

  18. Human Systems Interface Design Methods Using Ecological Interface Design Principles

    International Nuclear Information System (INIS)

    The results of this study categorized into two parts. The first part is the guidelines for EID designs. The procedure to observe for EID design is composed of 6 steps; 1) to define a target system, 2) to make an abstraction hierarchy model, 3) to check the link structure among each components included in the layers of abstraction hierarchy model, 4) to transform information requirements to variables, 5) to make the graphs related to each variables, 6) to check the graphs by visual display design principles and heuristic rules. The second part is an EID design alternative for nuclear power plant. The EID for high level function represents the energy balance and energy flow in each loop of nuclear power plant. The EID for middle level function represents the performance indicators of each equipment involved in the all processes of changing from coolants to steam. The EID for low level function represents the values measured in each equipment such as temperature, pressure, water level and so on

  19. Principles of Micellar Electrokinetic Capillary Chromatography Applied in Pharmaceutical Analysis

    Directory of Open Access Journals (Sweden)

    Árpád Gyéresi

    2013-02-01

    Full Text Available Since its introduction capillary electrophoresis has shown great potential in areas where electrophoretic techniques have rarely been used before, including here the analysis of pharmaceutical substances. The large majority of pharmaceutical substances are neutral from electrophoretic point of view, consequently separations by the classic capillary zone electrophoresis; where separation is based on the differences between the own electrophoretic mobilities of the analytes; are hard to achieve. Micellar electrokinetic capillary chromatography, a hybrid method that combines chromatographic and electrophoretic separation principles, extends the applicability of capillary electrophoretic methods to neutral analytes. In micellar electrokinetic capillary chromatography, surfactants are added to the buffer solution in concentration above their critical micellar concentrations, consequently micelles are formed; micelles that undergo electrophoretic migration like any other charged particle. The separation is based on the differential partitioning of an analyte between the two-phase system: the mobile aqueous phase and micellar pseudostationary phase. The present paper aims to summarize the basic aspects regarding separation principles and practical applications of micellar electrokinetic capillary chromatography, with particular attention to those relevant in pharmaceutical analysis.

  20. Safety principles and design management of Chashma Nuclear Power Plant

    International Nuclear Information System (INIS)

    The basic safety consideration and detailed design principles in the design of Chashma Nuclear Power Plant is elaborated. The management within the frame setting up by 'safety culture' and 'quality culture'

  1. Design Principles for Improving the Process of Publishing Open data

    OpenAIRE

    Zuiderwijk, A.M.G.; Janssen, M.F.W.H.A.; Choenni, R.; Meijer, R.F.

    2014-01-01

    · Purpose: Governments create large amounts of data. However, the publication of open data is often cumbersome and there are no standard procedures and processes for opening data. This blocks the easy publication of government data. The purpose of this paper is to derive design principles for improving the open data publishing process of public organizations. · Design/methodology/approach: Action Design Research (ADR) was employed to derive design principles. The literature was used as a foun...

  2. Applying the Principles of Homicide by Heart Attack.

    Science.gov (United States)

    Hlavaty, Leigh; Sung, LokMan

    2016-06-01

    Homicide by heart attack is a well-established model in forensic pathology that describes death elicited during or immediately after a criminal act where a threat or fear of physical injury is present. After its introduction nearly 4 decades ago, the principle has undergone a handful of modifications but still maintains its core concepts. All cases of this nature during a 20-year period at the Wayne County Medical Examiner's Office were compared and contrasted for demographics, circumstances and scene investigation, and autopsy and toxicology findings. Of the cases fulfilling the previously established criteria for homicide by heart attack, more than 80% displayed significant changes because of hypertension. This finding coincides with the high prevalence of hypertension in our urban population and highlights the significance of this disease. Also present were minor external and internal injuries in select cases, which reinforce the understanding that physical contact between the decedent and assailant does not preclude this diagnosis. PMID:27049661

  3. Principles of formation project creative thinking future designers during training

    OpenAIRE

    Derevyanko, N. V.; Classic Private University, Zaporozhe, Ukraine

    2012-01-01

    Article based on the basic provisions of the features thatcharacterize adult thinking and taking into account the specific design activity and design education, design principles of formation are determined and imaginative thinking in the future designers as professional thinking designers in the process of training in higher education institution.

  4. Universal Design: Process, Principles, and Applications

    Science.gov (United States)

    Burgstahler, Sheryl

    2009-01-01

    Designing any product or environment involves the consideration of many factors, including aesthetics, engineering options, environmental issues, safety concerns, industry standards, and cost. Typically, designers focus their attention on the average user. In contrast, universal design (UD), according to the Center for Universal Design," is the…

  5. Universal Design in Education: Principles and Applications

    Science.gov (United States)

    Burgstahler, Sheryl

    2009-01-01

    While courses, technology, and student services are typically designed for the narrow range of characteristics of the average student, the practice of universal design in education (UDE) considers people with a broad range of characteristics in the design of all educational products and environments. "UDE" goes beyond accessible design for people…

  6. Application of Lean Principles to Design Processes in Construction Consultancy Firms

    Directory of Open Access Journals (Sweden)

    Marzouk, Mohamed

    2011-12-01

    Full Text Available Simulation modelling and Lean principles have both been applied in the construction industry to improve work processes. The outcomes from their implementation are outstanding and have motivated construction researchers to seek means by which other aspects of construction production could benefit from this development. Therefore the aim of this research is to use computer simulation as a tool for assessing the impact of applying Lean principles to design processes in construction consultancy firms to aid in decision making at early stages of construction projects. A comprehensive model for the design process was built before the principles of Lean construction were depicted in the model. Through a detailed case study, it was concluded that applying Lean construction principles to the design process significantly helped to improve process efficiency, in terms of reduced process durations and increased resource utilisation.

  7. Applying the Principles of Augmented Learning to Photonics Laboratory Work

    CERN Document Server

    Fischer, Ulrich H P; Just, Jens-Uwe; Haupt, Matthias

    2007-01-01

    This paper introduces "OPTOTEACH", a new teaching system for photonics lab work, designed by Harz University and successfully released on the German market by HarzOptics. OPTOTEACH is the first POF-WDM teaching system, specifically designed to cover a multitude of lab experiments in the field of optical communication technology. It is illustrated, how this lab system is supplemented by a newly developed optical teaching software - "OPTOSOFT" - and how the combination of system and software creates a unique augmented learning environment. The paper details, how the didactic concept for the software was conceptualised and introduces the latest beta version. OPTOSOFT is specifically designed not only as an attachment to OPTOTEACH, it also allows students to rehearse various aspects of theoretical optics and experience a fully interactive and feature-rich self-learning environment. The paper further details the first experiences educators at Harz University have made working with the lab system as well as the tea...

  8. Applied ethics and eHealth: principles, identity, and RFID.

    OpenAIRE

    Duquenoy, Penny; Whitehouse, Diane

    2008-01-01

    The social and ethical implications of contemporary technologies are becoming an issue of steadily growing importance. This paper offers an overview in terms of identity and the field of ethics, and explores how these apply to eHealth in both theory and practice. The paper selects a specific circumstance in which these ethical issues can be explored. It focuses particularly on radio-frequency identifiers (RFID). It ends by discussing ethical issues more generally, and the practice of et...

  9. Welding As Science: Applying Basic Engineering Principles to the Discipline

    Science.gov (United States)

    Nunes, A. C., Jr.

    2010-01-01

    This Technical Memorandum provides sample problems illustrating ways in which basic engineering science has been applied to the discipline of welding. Perhaps inferences may be drawn regarding optimal approaches to particular welding problems, as well as for the optimal education for welding engineers. Perhaps also some readers may be attracted to the science(s) of welding and may make worthwhile contributions to the discipline.

  10. Human factor engineering applied to nuclear power plant design

    Energy Technology Data Exchange (ETDEWEB)

    Manrique, A. [TECNATOM SA, BWR General Electric Business Manager, Madrid (Spain); Valdivia, J.C. [TECNATOM SA, Operation Engineering Project Manager, Madrid (Spain); Jimenez, A. [TECNATOM SA, Operation Engineering Div. Manager, Madrid (Spain)

    2001-07-01

    For the design and construction of new nuclear power plants as well as for maintenance and operation of the existing ones new man-machine interface designs and modifications are been produced. For these new designs Human Factor Engineering must be applied the same as for any other traditional engineering discipline. Advantages of implementing adequate Human Factor Engineering techniques in the design of nuclear reactors have become not only a fact recognized by the majority of engineers and operators but also an explicit requirement regulated and mandatory for the new designs of the so called advanced reactors. Additionally, the big saving achieved by a nuclear power plant having an operating methodology which significantly decreases the risk of operating errors makes it necessary and almost vital its implementation. The first step for this is preparing a plan to incorporate all the Human Factor Engineering principles and developing an integral design of the Instrumentation and Control and Man-machine interface systems. (author)

  11. Human factor engineering applied to nuclear power plant design

    International Nuclear Information System (INIS)

    For the design and construction of new nuclear power plants as well as for maintenance and operation of the existing ones new man-machine interface designs and modifications are been produced. For these new designs Human Factor Engineering must be applied the same as for any other traditional engineering discipline. Advantages of implementing adequate Human Factor Engineering techniques in the design of nuclear reactors have become not only a fact recognized by the majority of engineers and operators but also an explicit requirement regulated and mandatory for the new designs of the so called advanced reactors. Additionally, the big saving achieved by a nuclear power plant having an operating methodology which significantly decreases the risk of operating errors makes it necessary and almost vital its implementation. The first step for this is preparing a plan to incorporate all the Human Factor Engineering principles and developing an integral design of the Instrumentation and Control and Man-machine interface systems. (author)

  12. Architectural design of heterogeneous metallic nanocrystals--principles and processes.

    Science.gov (United States)

    Yu, Yue; Zhang, Qingbo; Yao, Qiaofeng; Xie, Jianping; Lee, Jim Yang

    2014-12-16

    CONSPECTUS: Heterogeneous metal nanocrystals (HMNCs) are a natural extension of simple metal nanocrystals (NCs), but as a research topic, they have been much less explored until recently. HMNCs are formed by integrating metal NCs of different compositions into a common entity, similar to the way atoms are bonded to form molecules. HMNCs can be built to exhibit an unprecedented architectural diversity and complexity by programming the arrangement of the NC building blocks ("unit NCs"). The architectural engineering of HMNCs involves the design and fabrication of the architecture-determining elements (ADEs), i.e., unit NCs with precise control of shape and size, and their relative positions in the design. Similar to molecular engineering, where structural diversity is used to create more property variations for application explorations, the architectural engineering of HMNCs can similarly increase the utility of metal NCs by offering a suite of properties to support multifunctionality in applications. The architectural engineering of HMNCs calls for processes and operations that can execute the design. Some enabling technologies already exist in the form of classical micro- and macroscale fabrication techniques, such as masking and etching. These processes, when used singly or in combination, are fully capable of fabricating nanoscopic objects. What is needed is a detailed understanding of the engineering control of ADEs and the translation of these principles into actual processes. For simplicity of execution, these processes should be integrated into a common reaction system and yet retain independence of control. The key to architectural diversity is therefore the independent controllability of each ADE in the design blueprint. The right chemical tools must be applied under the right circumstances in order to achieve the desired outcome. In this Account, after a short illustration of the infinite possibility of combining different ADEs to create HMNC design

  13. Educational software design: applying models of learning

    OpenAIRE

    Richards, Stephen

    2011-01-01

    The model of learning adopted within this paper is the 'spreading ripples' (SR) model proposed by Race (1994). This model was chosen for two important reasons. First, it makes use of accessible ideas and language, .and is therefore simple. Second, .Race suggests that the model can be used in the design, of educational and training programmes (and can thereby be applied to the design of computer-based learning materials).DOI:10.1080/0968776960040303

  14. Applied game theory and optimal mechanism design

    OpenAIRE

    Zhang, Qi

    2014-01-01

    This thesis applies game theory to study optimal toehold bidding strategies during takeover competition, the problem of optimal design of voting rules and the design of package bidding mechanism to implement the core allocations. It documents three different research questions that are all related to auction theory. Chapter 2 develops a two-stage takeover game to explain toehold puzzle in the context of takeover. Potential bidders are allowed to acquire target shares in the open market, subje...

  15. Principle design and data of graphite components

    International Nuclear Information System (INIS)

    The High Temperature Engineering Test Reactor (HTTR) constructed by Japan Atomic Energy Research Institute (JAERI) is a graphite-moderated and helium-gas-cooled reactor with prismatic fuel elements of hexagonal blocks. The reactor internal structures of the HTTR are mainly made up of graphite components. As well known, the graphite is a brittle material and there were no available design criteria for brittle materials. Therefore, JAERI had to develop the design criteria taking account of the brittle fracture behavior. In this paper, concept and key specification of the developed graphite design criteria is described, and also an outline of the quality control specified in the design criteria is mentioned

  16. Toward Instructional Design Principles: Inducing Faraday's Law with Contrasting Cases

    Science.gov (United States)

    Kuo, Eric; Wieman, Carl E.

    2016-01-01

    Although physics education research (PER) has improved instructional practices, there are not agreed upon principles for designing effective instructional materials. Here, we illustrate how close comparison of instructional materials could support the development of such principles. Specifically, in discussion sections of a large, introductory…

  17. Robust design principles for reducing variation in functional performance

    DEFF Research Database (Denmark)

    Christensen, Martin Ebro; Howard, Thomas J.

    perceived quality of a product and efforts should be made to minimise it. The design principles are identified by a systematic decomposition of the Taguchi Transfer Function in combination with the use of existing literature and the authors’ experience. The paper presents 15 principles and describes their...

  18. Applying principles of health system strengthening to eye care

    Directory of Open Access Journals (Sweden)

    Karl Blanchet

    2012-01-01

    Full Text Available Understanding Health systems have now become the priority focus of researchers and policy makers, who have progressively moved away from a project-centred perspectives. The new tendency is to facilitate a convergence between health system developers and disease-specific programme managers in terms of both thinking and action, and to reconcile both approaches: one focusing on integrated health systems and improving the health status of the population and the other aiming at improving access to health care. Eye care interventions particularly in developing countries have generally been vertically implemented (e.g. trachoma, cataract surgeries often with parallel organizational structures or specialised disease specific services. With the emergence of health system strengthening in health strategies and in the service delivery of interventions there is a need to clarify and examine inputs in terms governance, financing and management. This present paper aims to clarify key concepts in health system strengthening and describe the various components of the framework as applied in eye care interventions.

  19. Applying Evidence-based Medicine Principles to Fracture Management

    Directory of Open Access Journals (Sweden)

    Joseph eBernstein

    2014-10-01

    Full Text Available Bone has the capacity to regenerate and not scar after injury—-sometimes leaving behind no evidence at all of a prior fracture. As surgeons capable of facilitating such healing, it becomes our responsibility to help choose a treatment that minimizes functional deficits and residual symptoms. And in the case of the geriatric hip fracture, we have seen the accumulation of a vast amount of evidence to help guide us.The best method we currently have for selecting treatment plans is by the practice of evidence-based medicine. According to the now accepted hierarchy, the best is called Level I evidence (eg, well performed randomized controlled trials—but this evidence is best only if it is available and appropriate. Lower forms of accepted evidence include cohort studies, case control studies, case series and case reports, and last, expert opinion--all of which can be potentially instructive. The hallmark of evidence-based treatment is not so much the reliance on evidence in general, but to use the best available evidence relative to the particular patient, the clinical setting and surgeon experience. Correctly applied, varying forms of evidence each have a role in aiding surgeons offer appropriate care for their patients--to help them best fix the fracture.

  20. Applying principles of health system strengthening to eye care

    Science.gov (United States)

    Blanchet, Karl; Patel, Daksha

    2012-01-01

    Understanding Health systems have now become the priority focus of researchers and policy makers, who have progressively moved away from a project-centred perspectives. The new tendency is to facilitate a convergence between health system developers and disease-specific programme managers in terms of both thinking and action, and to reconcile both approaches: one focusing on integrated health systems and improving the health status of the population and the other aiming at improving access to health care. Eye care interventions particularly in developing countries have generally been vertically implemented (e.g. trachoma, cataract surgeries) often with parallel organizational structures or specialised disease specific services. With the emergence of health system strengthening in health strategies and in the service delivery of interventions there is a need to clarify and examine inputs in terms governance, financing and management. This present paper aims to clarify key concepts in health system strengthening and describe the various components of the framework as applied in eye care interventions. PMID:22944762

  1. Publish Subscribe Systems Design and Principles

    CERN Document Server

    Tarkoma, Sasu

    2012-01-01

    This book offers an unified treatment of the problems solved by publish/subscribe, how to design and implement the solutions In this book, the author provides an insight into the publish/subscribe technology including the design, implementation, and evaluation of new systems based on the technology.  The book also addresses the basic design patterns and solutions, and discusses their application in practical application scenarios. Furthermore, the author examines current standards and industry best practices as well as recent research proposals in the area. Finally, necessary content ma

  2. The justification principle applied to Computed tomography exams

    International Nuclear Information System (INIS)

    The increasing use of imaging technologies and the installation of more sophisticated equipment in radiology services, such as multi-slice CT scanners have consequently increased the number of treated patients, as well as the collective doses to population. Radiation doses received from CT exams are higher than those received in conventional radiology. The optimal use of CT equipment, considering optimized techniques, and the justification of examinations, are imperative in order to minimize the undesirable effects of radiation. In this paper we do set out to the assessment of justification criteria applied for CT exams in a Cuban Hospital. The justification of prescribed tests by physicians was analyzed, assessing its incidence depending on the kind of studies and percentage (%) of positive and negative cases. The study was carried out in a Clinical Surgical Hospital in Havana City. This hospital has installed a Shimadzu SCT-7800TC helical single-slice device. The sample is made up of 81 patients, between 24 and 80 years old, both men and women. For all of them the pathology that causes the order of the exam as well as the existence of other previous tests, were considered. As a result of the assessment, the 56.8% of all cases turned out to be positives; the 55.5% only confirmed the pathologies and the 1.23% produced new evidences. On the other hand, the remaining 43.2% were negatives noting that the 65.3% of the patients there were not previous imaging tests. Skull exam was the most incidences compiling the 67.7% of cases, and it was the headache the most frequent clinical problem to perform the 41.1%. In terms of justification, the evaluation of prescriptions evidenced that CT exams were not justified in 43.2% of cases. As part of this last group, it was also found that 46.9% of clinical studies were negative. (author)

  3. The justification principle applied to computed tomography exams

    International Nuclear Information System (INIS)

    The increasing use of imaging technologies and the installation of more sophisticated equipment in radiology services, such as multi-slice CT scanners have consequently increased the number of treated patients, as well as the collective doses to population. Radiation doses received from CT exams are higher than those received in conventional radiology. The optimal use of CT equipment, considering optimized techniques, and the justification of examinations, are imperative in order to minimize the undesirable effects of radiation. In this paper we do set out to the assessment of justification criteria applied for CT exams in a Cuban Hospital. The justification of prescribed tests by physicians was analyzed, assessing its incidence depending on the kind of studies and percentage (%) of positive and negative cases. The study was carried out in a Clinical Surgical Hospital in Havana City. This hospital has installed a Shimadzu SCT-7800TC helical single-slice device. The sample is made up of 81 patients, between 24 and 80 years old, both men and women. For all of them the pathology that causes the order of the exam as well as the existence of other previous tests, were considered. As a result of the assessment, the 56.8% of all cases turned out to be positives; the 55.5% only confirmed the pathologies and the 1.23% produced new evidences. On the other hand, the remaining 43.2% were negatives noting that the 65.3% of the patients there were not previous imaging tests. Skull exam was the most incidences compiling the 67.7% of cases, and it was the headache the most frequent clinical problem to perform the 41.1%. In terms of justification, the evaluation of prescriptions evidenced that CT exams were not justified in 43.2% of cases. As part of this last group, it was also found that 46.9% of clinical studies were negative. (author)

  4. Scientific Collaborations: principles of WikiBridge Design

    CERN Document Server

    Leclercq, Eric

    2010-01-01

    Semantic wikis, wikis enhanced with Semantic Web technologies, are appropriate systems for community-authored knowledge models. They are particularly suitable for scientific collaboration. This paper details the design principles ofWikiBridge, a semantic wiki.

  5. Effective motion design applied to energy-efficient handling processes

    Energy Technology Data Exchange (ETDEWEB)

    Brett, Tobias

    2013-10-01

    Industrial robots are available in a large variety of mechanical alternatives regarding size, motor power, link length ratio or payload. The four major types of serial kinematics dominating the market are complemented by various parallel kinematics for special purpose. In contrast, few other path planning alternatives are applied in industrial robotics which are based on similar analytic solution principles. The objective of this thesis is to develop a systematic design method for artifacts in motion, to integrate motion design and mechanical design to enable new processes for production. For each design, a theoretical benchmark is developed, which cannot be attained by conventional robots in principle. A key performance indicator enables to measure the degree of goal achievement towards the benchmark during all design phases. Motion behaviors are identified on a local level by dynamic systems modeling and are integrated into new global behavior featuring a new quality, suitable for exceeding the design benchmark in industrial processes. Two exemplary handling robot designs are presented. The first concept enables motion behavior to consume less electrical power than kinetic energy transferred to and from its payload during motion. The second concept enables motion with four degrees of freedom by single motor stimulation, reducing idle power consumption on factor 4 towards conventional robots.

  6. Design principles for radiological protection instrumentation systems

    International Nuclear Information System (INIS)

    This Code of Practice takes the form of recommendations intended for designers and installers of Radiological Protection Instrumentation, and should also be of value to the newcomer to the R.P.I. field. Topics are discussed under the following headings: outline of R.P.I. requirements, specifying the requirement, satisfying the requirements, (overall design, availability and reliability, information display, human factors, power supplies, manufacture, quality assurance, testing, and cost analysis), supply, location and operation of the equipment, importance of documentation. (U.K.)

  7. Principles of waveform diversity and design

    CERN Document Server

    Wicks, Michael

    2011-01-01

    This is the first book to discuss current and future applications of waveform diversity and design in subjects such as radar and sonar, communications systems, passive sensing, and many other technologies. Waveform diversity allows researchers and system designers to optimize electromagnetic and acoustic systems for sensing, communications, electronic warfare or combinations thereof. This book enables solutions to problems, explaining how each system performs its own particular function, as well as how it is affected by other systems and how those other systems may likewise be affected. It is

  8. Models and design principles for teacher research

    NARCIS (Netherlands)

    Admiraal, Wilfried; Smit, Ben; Zwart, Rosanne

    2014-01-01

    Teacher research is a way to bridge the gap between theory and teaching practice. Various types of teacher research can be distinguished, including most commonly: action research, selfstudy, lesson study, design-based research, and scholarship of teaching and learning. All types of teacher research

  9. Principles of Designing Interpretable Optogenetic Behavior Experiments

    Science.gov (United States)

    Allen, Brian D.; Singer, Annabelle C.; Boyden, Edward S.

    2015-01-01

    Over the last decade, there has been much excitement about the use of optogenetic tools to test whether specific cells, regions, and projection pathways are necessary or sufficient for initiating, sustaining, or altering behavior. However, the use of such tools can result in side effects that can complicate experimental design or interpretation.…

  10. Wireless sensor networks principles, design and applications

    CERN Document Server

    Yang, Shuang-Hua

    2014-01-01

    Wireless Sensor Networks presents the latest practical solutions to the design issues presented in wireless-sensor-network-based systems. Novel features of the text, distributed throughout, include workable solutions, demonstration systems and case studies of the design and application of wireless sensor networks (WSNs) based on the first-hand research and development experience of the author, and the chapters on real applications: building fire safety protection; smart home automation; and logistics resource management. Case studies and applications illustrate the practical perspectives of: ·         sensor node design; ·         embedded software design; ·         routing algorithms; ·         sink node positioning; ·         co-existence with other wireless systems; ·         data fusion; ·         security; ·         indoor location tracking; ·         integrating with radio-frequency identification; and ·         In...

  11. Principles and Design Rationale of Composition Filters

    NARCIS (Netherlands)

    Bergmans, Lodewijk; Aksit, Mehmet; Filman, Robert E.; Elrad, Tzilla; Clarke, Siobhán; Akşit, Mehmet

    2004-01-01

    A wide range of aspect-oriented programming languages has appeared in the past years [7]. Current research on future generation AOP languages is addressing issues like flexibility, expressive power and safety. We think that it is important to understand the motivations and design decisions of the fi

  12. Applied statistical designs for the researcher

    CERN Document Server

    Paulson, Daryl S

    2003-01-01

    Showcasing a discussion of the experimental process and a review of basic statistics, this volume provides methodologies to identify general data distribution, skewness, and outliers. It features a unique classification of the nonparametric analogs of their parametric counterparts according to the strength of the collected data. Applied Statistical Designs for the Researcher discusses three varieties of the Student t test, including a comparison of two different groups with different variances; two groups with the same variance; and a matched, paired group. It introduces the analysis of variance and Latin Square designs and presents screening approaches to comparing two factors and their interactions.

  13. Design principles of metal-cutting machine tools

    CERN Document Server

    Koenigsberger, F

    1964-01-01

    Design Principles of Metal-Cutting Machine Tools discusses the fundamentals aspects of machine tool design. The book covers the design consideration of metal-cutting machine, such as static and dynamic stiffness, operational speeds, gearboxes, manual, and automatic control. The text first details the data calculation and the general requirements of the machine tool. Next, the book discusses the design principles, which include stiffness and rigidity of the separate constructional elements and their combined behavior under load, as well as electrical, mechanical, and hydraulic drives for the op

  14. Design principles for efficient, repeated jumpgliding

    International Nuclear Information System (INIS)

    Combined jumping and gliding locomotion, or ‘jumpgliding’, can be an efficient way for small robots or animals to travel over cluttered terrain. This paper presents functional requirements and models for a simple jumpglider which formalize the benefits and limitations of using aerodynamic surfaces to augment jumping ability. Analysis of the model gives insight into design choices and control strategies for higher performance and to accommodate special conditions such as a slippery launching surface. The model informs the design of a robotic platform that can perform repeated jumps using a carbon fiber spring and a pivoting wing. Experiments with two different versions of the platform agree with predictions from the model and demonstrate a significantly greater range, and lower cost-of-transport, than a comparable ballistic jumper. (papers)

  15. Design principles and typologies of zoos

    OpenAIRE

    Yılmaz, Serap; Özbilen, Ali

    2011-01-01

    The consumption of natural areas for the sake of urbanization results in extinction of various species. Therefore, introduction and education become important in order to protect natural environment and natural life system. Research in this area revealed that the zoos designed like natural life areas have great importance and that they contribute to the introduction of natural life and help people become conscious about natural life. This study aims to reveal the development of zoos in histor...

  16. First-principles design of nanomachines

    OpenAIRE

    Banavar, Jayanth R.; Cieplak, Marek; Hoang, Trinh Xuan; Maritan, Amos

    2009-01-01

    Learning from nature's amazing molecular machines, globular proteins, we present a framework for the predictive design of nano-machines. We show that the crucial ingredients for a chain molecule to behave as a machine are its inherent anisotropy and the coupling between the local Frenet coordinate reference frames of nearby monomers. We demonstrate that, even in the absence of heterogeneity, protein-like behavior is obtained for a simple chain molecule made up of just thirty hard spheres. Thi...

  17. Applying lean management principles to the creation of a postpartum hemorrhage care bundle.

    Science.gov (United States)

    Faulkner, Beth

    2013-10-01

    A lean management process is a set of interventions, each of which creates value for the customer. Lean management is not a new concept, but is relatively new to health care. Postpartum hemorrhage (PPH) is the most common cause of maternal death worldwide in both developing and developed countries. We applied lean management principles as an innovative approach to improving outcomes in patients with PPH. Initial results using principles of lean management indicated significant improvements in response time and family-centered care. When applied rigorously and throughout the organization, lean principles can have a dramatic effect on productivity, cost and quality. PMID:24138659

  18. Principle of equipartition of entransy dissipation for heat exchanger design

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    In the present work,a principle of equipartition of entransy dissipation(EoED) for heat exchanger design is established,which says that for a heat exchanger design with given heat duty and heat transfer area,the total entransy dissipation rate reaches the minimum when the local entransy dissipation rate is uniformly distributed along the heat exchanger.When the heat transfer coefficient is unfixed,the total entransy dissipation obtained by the EoED principle is less than that obtained by the principle of equipartition of temperature difference(EoTD).Furthermore,the exchanger effectiveness obtained by the EoED principle is larger than that obtained by the EoTD principle.When the heat transfer coefficient is fixed,the EoED principle is equivalent to the EoTD principle.We show that the equipartition of entropy production(EoEP) and EoED principles give rise to difference in entropy generation and entransy dissipation for a heat exchanger optimization design.The discrepancies are caused by distinct features of entropy production minimization and entransy dissipation minimization principles,the former is to optimize the design of heat exchanger by making the lost available work minimum,while the latter is not involved with heat-work conversion.It is found that the entropy generation number is not suitable for evaluating heat exchanger performance,since it directly depends on the inlet and outlet temperatures of working fluids.On the contrary,the entransy dissipation number is not directly related to the inlet and outlet temperatures of working fluids.Therefore,the entransy dissipation number is more suitable for serving as a criterion to evaluate heat exchanger performance.

  19. Wind turbine technology principles and design

    CERN Document Server

    Adaramola, Muyiwa

    2014-01-01

    IntroductionPart I: AerodynamicsWind Turbine Blade Design; Peter J. Schubel and Richard J. CrossleyA Shrouded Wind Turbine Generating High Output Power with Wind-Lens Technology; Yuji Ohya and Takashi KarasudaniEcomoulding of Composite Wind Turbine Blades Using Green Manufacturing RTM Process; Brahim AttafAerodynamic Shape Optimization of a Vertical-Axis Wind Turbine Using Differential Evolution; Travis J. Carrigan, Brian H. Dennis, Zhen X. Han, and Bo P. WangPart II: Generators and Gear Systems

  20. First-principles design of nanomachines.

    Science.gov (United States)

    Banavar, Jayanth R; Cieplak, Marek; Hoang, Trinh Xuan; Maritan, Amos

    2009-04-28

    Learning from nature's amazing molecular machines, globular proteins, we present a framework for the predictive design of nanomachines. We show that the crucial ingredients for a chain molecule to behave as a machine are its inherent anisotropy and the coupling between the local Frenet coordinate reference frames of nearby monomers. We demonstrate that, even in the absence of heterogeneity, protein-like behavior is obtained for a simple chain molecule made up of just 30 hard spheres. This chain spontaneously switches between 2 distinct geometries, a single helix and a dual helix, merely because of thermal fluctuations. PMID:19359489

  1. Preserving SSC Design Function Using RCM Principles

    International Nuclear Information System (INIS)

    Reliability-Centered Maintenance (RCM) can be defined as an approach that employs preventive, predictive, proactive, and reactive maintenance practices and strategies in an integrated manner to increase the probability that a Structure, System, or Component (SSC) will function as designed over its life cycle with optimum maintenance. The goal of RCM is to preserve the SSC intended design function at the lowest cost by developing a maintenance strategy that is supported by sound technical and economic justification. RCM has been used extensively by the aircraft, space, defense, power generation, and manufacturing industries where functional failures of SSCs can have the potential to compromise worker or public safety, cause adverse environmental impact, cause loss of production, and/or result in excessive damage to critical SSCs. This paper provides a framework for performing an RCM analysis in support of DOE Order 430.1A (Life Cycle Asset Management) and DOE Order 420.1B (Facility Safety). The influence of RCM on the various aspects of the maintenance program including the work control process is also discussed

  2. PRINCIPLE OF POST-PRODUCTION DESIGN OF HYDRAULIC ACTUATORS

    OpenAIRE

    A. V. Puzanov

    2015-01-01

    In work the problem of design-technology preparation of production of hydraulic actuators is staticized. The structure and business processes of design and production are analysed. Methods and means of reorganization of project works for the purpose of cutting-down of time of preparation of production are offered. The directions of reorganization of process of design are formulated. The principle of carrying out procedures of design-technology preparation of production of hydraulic actuators ...

  3. Applying the Principles of Systems Engineering and Project Management to Optimize Scientific Research

    Science.gov (United States)

    Peterkin, Adria J.

    2016-01-01

    Systems Engineering is an interdisciplinary practice that analyzes different facets of a suggested area to properly develop and design an efficient system guided by the principles and restrictions of the science community. When entering an institution with quantitative and analytical scientific theory it is important to make sure that all parts of a system correlates in a structured and systematic manner so that all areas of intricacy will be prevented or quickly deduced. My research focused on interpreting and implementing Systems Engineering techniques in the construction, integration and operation of a NASA Radio Jove Kit to Observe Jupiter radio emissions. Jupiter emissions read at very low frequencies so when building the telescope it had to be able to read less than 39.5 MHz. The projected outcome was to receive long L-bursts and short S-burts signals; however, during the time of observation Jupiter was in conjunction with the Sun. We then decided to use the receiver built from the NASA Radio Jove Kit to hook it up to the Karl Jansky telescope to make an effort to listen to solar flares as well, nonetheless, we were unable to identify these signals and further realized they were noise. The overall project was a success in that we were able to apply and comprehend, the principles of Systems Engineering to facilitate the build.

  4. Zero Energy Buildings – Design Principles and Built Examples

    DEFF Research Database (Denmark)

    for the development of zero energy houses. These strategies and technologies are illustrated through simple design principles and built examples • identify technical and architectural potentials and challenges related to design strategies of crucial importance to the development of zero energy houses...

  5. Basic principles governing the design of magnetic switches

    International Nuclear Information System (INIS)

    The idea of using saturable reactors as the basis of high power pulse generators is not a new concept, but there have been few recent applications of this technology. Here the principle of magnetic pulse generation is briefly described and some of the basic guidelines used to design these circuits are discussed. A demonstration of the principles by a small scale pulse amplifier is presented, and finally there is an extrapolation to a large scale system

  6. Authentic tasks in higher education: Studying design principles for assessment

    OpenAIRE

    Keulen, H. van; Van den Berg, I.; Ramaekers, S.

    2006-01-01

    Students may benefit significantly from learning through authentic tasks. But how do we assess their learning outcomes, taking into account the specific characteristics of authentic tasks? In the second presentation of this symposium on design principles for authentic tasks we present and discuss principles for assessment procedures in authentic tasks from three different domains: clinical reasoning in Veterinary Science; internships in Medicine; and essay writing in History, all at Utrecht U...

  7. Applying vision feedback to crane controller design

    Science.gov (United States)

    Lee, Lun-Hui; Huang, Pei-Hsiang; Pan, Shing-Tai; Wijaya Lie, Handra; Chiang, Tung-Chien; Chang, Cheng-Yuan

    2015-01-01

    Encoders are generally used to track the motion of industrial mechanisms. However, the information obtained by encoders may have errors due to encoder aging or mechanism-design problem. Therefore, information by visual feedback is a better way to track the movement of industrial mechanisms. However, image information costs lots of computing effort so it is not easy to be used in real-time control applications. This manuscript derives a simple but effective visual feedback method to follow the target and the image information is obtained only by a general handy camcorder. Besides, the proposed method can track multi-locations in a meantime. Fast image pattern recognition and localisation of the colour histogram by using a moving tracking block is applied to increase the calculation speed. Finally, the obtained locations information by the proposed visual feedback method is applied in an industrial crane control system to verify the effectiveness.

  8. Instructional Audio Guidelines: Four Design Principles to Consider for Every Instructional Audio Design Effort

    Science.gov (United States)

    Carter, Curtis W.

    2012-01-01

    This article contends that instructional designers and developers should attend to four particular design principles when creating instructional audio. Support for this view is presented by referencing the limited research that has been done in this area, and by indicating how and why each of the four principles is important to the design process.…

  9. Patterns, principles, and practices of domain-driven design

    CERN Document Server

    Millett, Scott

    2015-01-01

    Methods for managing complex software construction following the practices, principles and patterns of Domain-Driven Design with code examples in C# This book presents the philosophy of Domain-Driven Design (DDD) in a down-to-earth and practical manner for experienced developers building applications for complex domains. A focus is placed on the principles and practices of decomposing a complex problem space as well as the implementation patterns and best practices for shaping a maintainable solution space. You will learn how to build effective domain models through the use of tactical pat

  10. Principle and Method for Structural Design of Digital Woven Fabric

    Institute of Scientific and Technical Information of China (English)

    ZHOU Jiu; NG Frankie

    2006-01-01

    Digital woven textiles are one of the latest research areas of digital textiles. The key of research on design of digital woven fabrics lies in structural design. Nowadays, the application of digital design technology has fundamentally changed the concept of structural design of woven fabric,giving rise to design methods and effects that were deemed impossible before. A study has been carried out to analyze the nature of woven structures and the methods of structural design. This paper proposes an innovative principle and method of structural design under digital design concept, on which the design of digital gamut weaves and establishment of weave-database were presented to meet the requirement of balanced interlacement. It is envisaged that the results of this study will enhance future research in creation of digital woven fabrics, with particular emphasis on digital jacquard fabrics. Meanwhile, this study is also laid the foundation for the intelligent design of woven textile.

  11. Student design projects in applied acoustics.

    Science.gov (United States)

    Bös, Joachim; Moritz, Karsten; Skowronek, Adam; Thyes, Christian; Tschesche, Johannes; Hanselka, Holger

    2012-03-01

    This paper describes a series of student projects which are intended to complement theoretical education in acoustics and engineering noise control with practical experience. The projects are also intended to enhance the students' ability to work in a team, to manage a project, and to present their results. The projects are carried out in close cooperation with industrial partners so that the students can get a taste of the professional life of noise control engineers. The organization of such a project, its execution, and some of the results from the most recent student project are presented as a demonstrative example. This latest project involved the creation of noise maps of a production hall, the acoustic analysis of a packaging machine, and the acoustic analysis of a spiral vibratory conveyor. Upon completion of the analysis, students then designed, applied, and verified some simple preliminary noise reduction measures to demonstrate the potential of these techniques. PMID:22423803

  12. DATA CRYSTALLIZATION APPLIED FOR DESIGNING NEW PRODUCTS

    Institute of Scientific and Technical Information of China (English)

    Kenichi HORIE; Yoshiharu MAENO; Yukio OHSAWA

    2007-01-01

    It is only the observable part of the real world that can be stored in data.For such incomplete and ill-structured data,data crystallizing aims at presenting the hidden structure among events including unobservable events.This is realized by data crystallization,where dummy items,corresponding to potential existence ofunobservable events,are inserted to the given data.These dummy items and their relations with observable events are visualized by applying KeyGraph to the data with dummy items,like the crystallization of snow where dusts are involved in the formation of crystallization of water molecules.For tuning the granularity level of structure to be visualized,the tool of data crystallization is integrated with human's process of understanding significant scenarios in the real world.This basic method is expected to be applicable for various real world domains where previous methods of chance-discovery lead human to successful decision making.In this paper,we apply the data crystallization with human-interactive annealing (DCHA) to the design of products in a real company.The results show its effect to industrial decision making.

  13. Modern and traditional urban design concepts and principles in Iran

    OpenAIRE

    Ferdowsian, Fereshteh

    2002-01-01

    The expected result of this work is a survey on timeless design principles with traditional origion that can create new towns and conserve historic cities, that respect the Iranian traditional way of life and cultural identity in their modern living environment.

  14. Virtual Worlds; Real Learning: Design Principles for Engaging Immersive Environments

    Science.gov (United States)

    Wu (u. Sjarpm)

    2012-01-01

    The EMDT master's program at Full Sail University embarked on a small project to use a virtual environment to teach graduate students. The property used for this project has evolved our several iterations and has yielded some basic design principles and pedagogy for virtual spaces. As a result, students are emerging from the program with a better grasp of future possibilities.

  15. Design Principles for Improving the Process of Publishing Open data

    NARCIS (Netherlands)

    Zuiderwijk, A.M.G.; Janssen, M.F.W.H.A.; Choenni, R. .; Meijer, R.F.

    2014-01-01

    · Purpose: Governments create large amounts of data. However, the publication of open data is often cumbersome and there are no standard procedures and processes for opening data. This blocks the easy publication of government data. The purpose of this paper is to derive design principles for improv

  16. Design Principles for Cell Phone Learning in EFL

    Science.gov (United States)

    Wang, Feihong

    2010-01-01

    Cell phone learning (C-learning), as an instructional approach, has been gaining more and more attention in the field of teaching English as a foreign language (EFL) in the last 10 years. While studies have proved C-learning an effective instructional approach in research settings, a review of literature indicates the lack of design principles to…

  17. Computers as components principles of embedded computing system design

    CERN Document Server

    Wolf, Marilyn

    2012-01-01

    Computers as Components: Principles of Embedded Computing System Design, 3e, presents essential knowledge on embedded systems technology and techniques. Updated for today's embedded systems design methods, this edition features new examples including digital signal processing, multimedia, and cyber-physical systems. Author Marilyn Wolf covers the latest processors from Texas Instruments, ARM, and Microchip Technology plus software, operating systems, networks, consumer devices, and more. Like the previous editions, this textbook: Uses real processors to demonstrate both technology and tec

  18. Design for social innovation: emerging principles and approaches

    OpenAIRE

    Chick, Anne

    2012-01-01

    Anne Chick’s essay ‘Design for social innovation: emerging principles and approaches’, rounds off this collection by addressing key challenges that we all face as designers in embedding social- and bio-sustainability in our practices. She asks us to consider the complex social issues in this emerging new research landscape and what strategies, tools, methods and collaborations are needed to be effective participants in providing solutions and meaningful policy changes.

  19. Applying Software Design Patterns on iOS Application : A Case Study: Finnkino

    OpenAIRE

    Atik, Mohammad Abdullah

    2014-01-01

    Software developers practice software design patterns and principles to solve commonly occurring problems while ensuring extensible robust and maintainable system. The thesis aimed to study a subset of software patterns and principles. The practical goal of the thesis was to develop an iOS application with proper patterns applied. The main focus was to recognize which pattern would suit for an application’s various design challenges and what benefits would be harnessed by it. The study ai...

  20. 39 CFR 3050.10 - Analytical principles to be applied in the Postal Service's annual periodic reports to the...

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Analytical principles to be applied in the Postal... REGULATORY COMMISSION PERSONNEL PERIODIC REPORTING § 3050.10 Analytical principles to be applied in the... Commission, the Postal Service shall use only accepted analytical principles. With respect to its...

  1. 12 CFR 223.24 - What valuation principles apply to extensions of credit secured by affiliate securities?

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false What valuation principles apply to extensions... THEIR AFFILIATES (REGULATION W) Valuation and Timing Principles Under Section 23A § 223.24 What valuation principles apply to extensions of credit secured by affiliate securities? (a) Valuation...

  2. Applying principles of Design For Assembly to ITER maintenance operations

    NARCIS (Netherlands)

    Heemskerk, C.; de M. Baar,; Elzendoorn, B.; Koning, J.; Verhoeven, T.; de Vreede, F.

    2009-01-01

    In ITER, maintenance operations in the vessel and in the Hot Cell will be largely done by Remote Handling (RH). Remotely performed maintenance actions tend to be more time-costly than actions performed by direct human access. With a human operator in the control loop and adequate situational feedbac

  3. Applying Operating System Principles to SDN Controller Design

    OpenAIRE

    Monaco, Matthew; Michel, Oliver; Keller, Eric

    2015-01-01

    Rather than creating yet another network controller which provides a framework in a specific (potentially new) programming language and runs as a monolithic application, in this paper we extend an existing operating system and leverage its software ecosystem in order to serve as a practical SDN controller. This paper introduces yanc, a controller platform for software-defined networks which exposes the network configuration and state as a file system, enabling user and system applications to ...

  4. 41 CFR 102-3.95 - What principles apply to the management of advisory committees?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What principles apply to the management of advisory committees? 102-3.95 Section 102-3.95 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION GENERAL...

  5. Innovative Principle and Method for Digital Jacquard Fabric Designing

    Institute of Scientific and Technical Information of China (English)

    ZHOU Jiu; NG Fran-kie; SZETO Y C; HUI C L

    2007-01-01

    Digital jacquard fabric has its design concept and method directly borrowed from computer images and color modes, which enabled creation of jacquard fabric design that is far beyond what freehand patterns can express. In this paper, the principles of digital jacquard fabric design were classified into two parts: colorless mode and colorful mode, and an innovative layered combination design method has been suggested contenting with this new design concept, by which digital jacquard fabric can be designed from colorless single-layer structure to colorful compound structure. As a result, designed colorless and colorful jacquard fabrics are capable of expressing picturesque and photo-realistic effects with a mega level color number on face of fabric. It is envisaged that the results of the study are of tremendous benefit to the creation of new jacquard fabric ith an inimitable digital effect and this creation pose no problem in mass production.

  6. Design Principles for Effective Knowledge Discovery from Big Data

    Energy Technology Data Exchange (ETDEWEB)

    Begoli, Edmon [ORNL; Horey, James L [ORNL

    2012-01-01

    Big data phenomenon refers to the practice of collection and processing of very large data sets and associated systems and algorithms used to analyze these massive datasets. Architectures for big data usually range across multiple machines and clusters, and they commonly consist of multiple special purpose sub-systems. Coupled with the knowledge discovery process, big data movement offers many unique opportunities for organizations to benefit (with respect to new insights, business optimizations, etc.). However, due to the difficulty of analyzing such large datasets, big data presents unique systems engineering and architectural challenges. In this paper, we present three sys- tem design principles that can inform organizations on effective analytic and data collection processes, system organization, and data dissemination practices. The principles presented derive from our own research and development experiences with big data problems from various federal agencies, and we illustrate each principle with our own experiences and recommendations.

  7. Zero Energy Buildings – Design Principles and Built Examples

    DEFF Research Database (Denmark)

    Bejder, Anne Kirkegaard; Knudstrup, Mary-Ann; Jensen, Rasmus Lund;

    . The purpose of this booklet is to support the integrated design process and co-operation between different professions. The subject areas are therefore described at a general level, to provide the engineer with an insight into the techniques used by the architect, and vice versa. Additionally...... for the development of zero energy houses. These strategies and technologies are illustrated through simple design principles and built examples • identify technical and architectural potentials and challenges related to design strategies of crucial importance to the development of zero energy houses...

  8. Digital sonar design in underwater acoustics principles and applications

    CERN Document Server

    Li, Qihu

    2012-01-01

    "Digital Sonar Design in Underwater Acoustics Principles and Applications" provides comprehensive and up-to-date coverage of research on sonar design, including the basic theory and techniques of digital signal processing, basic concept of information theory, ocean acoustics, underwater acoustic signal propagation theory, and underwater signal processing theory. This book discusses the general design procedure and approaches to implementation, the design method, system simulation theory and techniques, sonar tests in the laboratory, lake and sea, and practical validation criteria and methods for digital sonar design. It is intended for researchers in the fields of underwater signal processing and sonar design, and also for navy officers and ocean explorers. Qihu Li is a professor at the Institute of Acoustics, Chinese Academy of Sciences, and an academician of the Chinese Academy of Sciences.

  9. Design principles of a web interface for monitoring tools

    Energy Technology Data Exchange (ETDEWEB)

    Aiftimiei, C; Pra, S D; Fantinel, S [INFN-Padova, Padova (Italy); Andreozzi, S; Fattibene, E; Misurelli, G [INFN-CNAF, Bologna (Italy); Cuscela, G; Donvito, G; Dudhalkar, V; Maggi, G; Pierro, A [INFN-Bari, Bari (Italy)], E-mail: giuseppe.misurelli@cnaf.infn.it, E-mail: enrico.fattibene@cnaf.infn.it

    2008-07-15

    A monitoring tool of a complex Grid system can gather a huge amount of information that have to be presented to the users in the most comprehensive way. Moreover different types of consumers could be interested in inspecting and analyzing different subsets of data. The main goal in designing a Web interface for the presentation of monitoring information is to organize the huge amount of data in a simple, user-friendly and usable structure. One more problem is to consider different approaches, skills and interests that all the possible categories of users have in looking for the desired information. Starting from the Information Architecture guidelines for the Web, it is possible to design Web interfaces towards a closer user experience and to deal with an advanced user interaction through the implementation of many Web standard technologies. In this paper, we will present a number of principles for the design of Web interface for monitoring tools that provide a wider, richer range of possibilities for what concerns the user interaction. These principles are based on an extensive review of the current literature in Web design and on the experience with the development of the GridICE monitoring tool. The described principles can drive the evolution of the Web interface of Grid monitoring tools.

  10. Design principles of a web interface for monitoring tools

    International Nuclear Information System (INIS)

    A monitoring tool of a complex Grid system can gather a huge amount of information that have to be presented to the users in the most comprehensive way. Moreover different types of consumers could be interested in inspecting and analyzing different subsets of data. The main goal in designing a Web interface for the presentation of monitoring information is to organize the huge amount of data in a simple, user-friendly and usable structure. One more problem is to consider different approaches, skills and interests that all the possible categories of users have in looking for the desired information. Starting from the Information Architecture guidelines for the Web, it is possible to design Web interfaces towards a closer user experience and to deal with an advanced user interaction through the implementation of many Web standard technologies. In this paper, we will present a number of principles for the design of Web interface for monitoring tools that provide a wider, richer range of possibilities for what concerns the user interaction. These principles are based on an extensive review of the current literature in Web design and on the experience with the development of the GridICE monitoring tool. The described principles can drive the evolution of the Web interface of Grid monitoring tools

  11. Applying the V Model and Axiomatic Design in the Domain of IT Architecture Practice

    NARCIS (Netherlands)

    Tarenskeen, Debbie; Bakker, René; Joosten, Stef

    2015-01-01

    This paper applies and discusses the principles of Axiomatic Design for changing IT architecture in health care. It presents three case studies positioned in the field of Enterprise architecture that explore how IT architects, as professionals, manage change and re-design the structure of the IT sys

  12. Client Mobile Software Design Principles for Mobile Learning Systems

    Directory of Open Access Journals (Sweden)

    Qing Tan

    2009-01-01

    Full Text Available In a client-server mobile learning system, client mobile software must run on the mobile phone to acquire, package, and send student’s interaction data via the mobile communications network to the connected mobile application server. The server will receive and process the client data in order to offer appropriate content and learning activities. To develop the mobile learning systems there are a number of very important issues that must be addressed. Mobile phones have scarce computing resources. They consist of heterogeneous devices and use various mobile operating systems, they have limitations with their user/device interaction capabilities, high data communications cost, and must provide for device mobility and portability. In this paper we propose five principles for designing Client mobile learning software. A location-based adaptive mobile learning system is presented as a proof of concept to demonstrate the applicability of these design principles.

  13. Using Persuasive Design Principles in Motivational Feeling towards Children Dental Anxiety (CDA)

    Science.gov (United States)

    Salam, Sobihatun Nur-Abdul; Yahaya, Wan Ahmad Jaafar-Wan; Ali, Azillah-Mohd

    This paper is focusing the potential use of persuasive design principles in motivating children's dental anxiety. The main intention of the paper is to emphasize an attempt of how persuasive design principle can be designed into educational material using CD ROM based multimedia learning environment to overcome the CDA. Firstly, we describe a problem domain which discuss about the universal feeling of CDA and secondly the current practices in handling those negative feelings. Thirdly, the conceptual background of PMLE and how the principle has been applied in designing the information interfaces and presentation of a persuasive multimedia learning environment (PMLE) are described. Fourthly, an experimental design was used to validate the effects of prototype which assessed children dental anxiety level before and after the demonstration and utilization of a PMLE. Primary school children age between seven and nine years old are selected as respondents. Fifthly, the result of the study has revealed the feedback from children regarding baseline test and children dental anxiety test. It shows how by using persuasive design principles as an overall strategy in designing PMLE was able to motivate children feelings towards dental anxiety and could let the children behave in a good manner for dental visit in the future.

  14. The prescriptive quality of 11 design principles for knowledge productivity

    OpenAIRE

    Verdonschot, Suzanne G.M.; Kessels, Joseph W.M.

    2008-01-01

    This study explores the learning processes that contribute to knowledge productivity: gradual improvement and radical innovation of an organisation’s operating procedures, products, and services, based on the development and application of new knowledge. The research is based on the assumption that innovation is the result of a series of powerful social learning processes. Previous research revealed a set of eleven design principles that reflect factors that really matter in an innovation pro...

  15. Instructional design principles for cooperative learning in Asia

    OpenAIRE

    Nguyen, Phuong-Mai; Terlouw, C.; Pilot, A.

    2006-01-01

    Social sciences possess a plethora of studies about cooperative learning. However, most of these researches have been conducted mainly by and on Westerners with fundamental assumptions based on Western values. Many recent intercultural studies proved that people cooperate with each other differently across cultures. This suggests a need of different model and different design principles for Cooperative Learning(CL) in non-Western cultures. Particular focus of this paper is on Confucian Herita...

  16. Greenhouse design applying CFD for Indonesian conditions

    NARCIS (Netherlands)

    Campen, J.B.

    2005-01-01

    In the design phase of a test site in Indonesia computational fluid dynamics has been used to design the construction of the plastic greenhouse. Greenhouses in Indonesia are built to protect the crop from heavy rain and insects. The climate in four different greenhouse designs is calculated without

  17. Seeing is believing: good graphic design principles for medical research.

    Science.gov (United States)

    Duke, Susan P; Bancken, Fabrice; Crowe, Brenda; Soukup, Mat; Botsis, Taxiarchis; Forshee, Richard

    2015-09-30

    Have you noticed when you browse a book, journal, study report, or product label how your eye is drawn to figures more than to words and tables? Statistical graphs are powerful ways to transparently and succinctly communicate the key points of medical research. Furthermore, the graphic design itself adds to the clarity of the messages in the data. The goal of this paper is to provide a mechanism for selecting the appropriate graph to thoughtfully construct quality deliverables using good graphic design principles. Examples are motivated by the efforts of a Safety Graphics Working Group that consisted of scientists from the pharmaceutical industry, Food and Drug Administration, and academic institutions. PMID:26112209

  18. Industrial and process furnaces principles, design and operation

    CERN Document Server

    Jenkins, Barrie

    2014-01-01

    Furnaces sit at the core of all branches of manufacture and industry, so it is vital that these are designed and operated safely and effi-ciently. This reference provides all of the furnace theory needed to ensure that this can be executed successfully on an industrial scale. Industrial and Process Furnaces: Principles, 2nd Edition provides comprehensive coverage of all aspects of furnace operation and design, including topics essential for process engineers and operators to better understand furnaces. This includes: the combustion process and its control, furnace fuels, efficiency,

  19. The Logistic Principles for Fast Flexible Strategy Design of the Company in Crisis Time

    Directory of Open Access Journals (Sweden)

    Dušan Malindžák

    2011-06-01

    Full Text Available The article deals with design of the logistic principles enabling an enterpriseto create a strategy flexible in terms of business and marketingand stable and steady in terms of manufacturing. In order to create astrategy model the following principles can be applied: shortening theperiod of capacity planning combined with flexible planning, syncro– MRP (Material Required Planning principle, the application of forecastingin capacity planning, creation with partners of one of the cooperationforms such as supply chain, demand chain, lean supply chain,agile supply chain, leagile supply chain, and using the dbr (Drum BufferRope, APS(Advanced Planning System and SCP (Supply ChainPlanning systems. The article describes application of this principlefor model design of the flexible strategy for Chemosvit fólie a. s. company,and the results of this application in the crisis time 2009–2011.

  20. Semiconductor-inspired design principles for superconducting quantum computing.

    Science.gov (United States)

    Shim, Yun-Pil; Tahan, Charles

    2016-01-01

    Superconducting circuits offer tremendous design flexibility in the quantum regime culminating most recently in the demonstration of few qubit systems supposedly approaching the threshold for fault-tolerant quantum information processing. Competition in the solid-state comes from semiconductor qubits, where nature has bestowed some very useful properties which can be utilized for spin qubit-based quantum computing. Here we begin to explore how selective design principles deduced from spin-based systems could be used to advance superconducting qubit science. We take an initial step along this path proposing an encoded qubit approach realizable with state-of-the-art tunable Josephson junction qubits. Our results show that this design philosophy holds promise, enables microwave-free control, and offers a pathway to future qubit designs with new capabilities such as with higher fidelity or, perhaps, operation at higher temperature. The approach is also especially suited to qubits on the basis of variable super-semi junctions. PMID:26983379

  1. Semiconductor-inspired design principles for superconducting quantum computing

    Science.gov (United States)

    Shim, Yun-Pil; Tahan, Charles

    2016-01-01

    Superconducting circuits offer tremendous design flexibility in the quantum regime culminating most recently in the demonstration of few qubit systems supposedly approaching the threshold for fault-tolerant quantum information processing. Competition in the solid-state comes from semiconductor qubits, where nature has bestowed some very useful properties which can be utilized for spin qubit-based quantum computing. Here we begin to explore how selective design principles deduced from spin-based systems could be used to advance superconducting qubit science. We take an initial step along this path proposing an encoded qubit approach realizable with state-of-the-art tunable Josephson junction qubits. Our results show that this design philosophy holds promise, enables microwave-free control, and offers a pathway to future qubit designs with new capabilities such as with higher fidelity or, perhaps, operation at higher temperature. The approach is also especially suited to qubits on the basis of variable super-semi junctions. PMID:26983379

  2. Semiconductor-inspired design principles for superconducting quantum computing

    Science.gov (United States)

    Shim, Yun-Pil; Tahan, Charles

    2016-03-01

    Superconducting circuits offer tremendous design flexibility in the quantum regime culminating most recently in the demonstration of few qubit systems supposedly approaching the threshold for fault-tolerant quantum information processing. Competition in the solid-state comes from semiconductor qubits, where nature has bestowed some very useful properties which can be utilized for spin qubit-based quantum computing. Here we begin to explore how selective design principles deduced from spin-based systems could be used to advance superconducting qubit science. We take an initial step along this path proposing an encoded qubit approach realizable with state-of-the-art tunable Josephson junction qubits. Our results show that this design philosophy holds promise, enables microwave-free control, and offers a pathway to future qubit designs with new capabilities such as with higher fidelity or, perhaps, operation at higher temperature. The approach is also especially suited to qubits on the basis of variable super-semi junctions.

  3. Design principles for rapid folding of knotted DNA nanostructures.

    Science.gov (United States)

    Kočar, Vid; Schreck, John S; Čeru, Slavko; Gradišar, Helena; Bašić, Nino; Pisanski, Tomaž; Doye, Jonathan P K; Jerala, Roman

    2016-01-01

    Knots are some of the most remarkable topological features in nature. Self-assembly of knotted polymers without breaking or forming covalent bonds is challenging, as the chain needs to be threaded through previously formed loops in an exactly defined order. Here we describe principles to guide the folding of highly knotted single-chain DNA nanostructures as demonstrated on a nano-sized square pyramid. Folding of knots is encoded by the arrangement of modules of different stability based on derived topological and kinetic rules. Among DNA designs composed of the same modules and encoding the same topology, only the one with the folding pathway designed according to the 'free-end' rule folds efficiently into the target structure. Besides high folding yield on slow annealing, this design also folds rapidly on temperature quenching and dilution from chemical denaturant. This strategy could be used to design folding of other knotted programmable polymers such as RNA or proteins. PMID:26887681

  4. A Framework for Understanding and Applying Ethical Principles in Network and Security Research

    Science.gov (United States)

    Kenneally, Erin; Bailey, Michael; Maughan, Douglas

    Current information and communications technology poses a variety of ethical challenges for researchers. In this paper, we present an intellectual framework for understanding and applying ethical principles in networking and security research rooted in the guidance suggested by an ongoing Department of Homeland Security working group on ethics. By providing this prototype ethical impact assessment, we seek to encourage community feedback on the working group's nascent efforts and spur researchers to concretely evaluate the ethical impact of their work.

  5. Iterative approach to the Schwinger variational principle applied to electron—molecular-ion collisions

    OpenAIRE

    Lucchese, Robert R.; McKoy, Vincent

    1981-01-01

    We present a study of electron—molecular-ion collisions. The scattering equations are solved using an iterative approach to the Schwinger variational principle. These equations are formulated using the Coulomb Green's function to properly treat the long-range Coulomb tail of the molecular-ion potential. We apply this approach to electron—hydrogen-molecular-ion collisions in the static-exchange approximation. We obtain elastic differential cross sections, and also use the continuum states from...

  6. Principle of bio-inspired insect wing rotational hinge design

    Science.gov (United States)

    Fei, Fan

    A principle for designing and fabricating bio-inspired miniature artificial insect flapping wing using flexure rotational hinge design is presented. A systematic approach of selecting rotational hinge stiffness value is proposed. Based on the understanding of flapping wing aerodynamics, a dynamic simulation is constructed using the established quasi-steady model and the wing design. Simulations were performed to gain insight on how different parameters affect the wing rotational response. Based on system resonance a model to predict the optimal rotational hinge stiffness based on given wing parameter and flapping wing kinematic is proposed. By varying different wing parameters, the proposed method is shown to be applicable to a wide range of wing designs with different sizes and shapes. With the selected hinge stiffness value, aspects of the rotational joint design is discussed and an integrated wing-hinge structure design using laminated carbon fiber and polymer film is presented. Manufacturing process of such composite structure is developed to achieve high accuracy and repeatability. The yielded hinge stiffness is verified by measurements. To validate the proposed model, flapping wing experiments were conducted. A flapping actuation set up is built using DC motor and a controller is implemented on a microcontroller to track desired wing stroke kinematic. Wing stroke and rotation kinematic were extracted using a high speed camera and the lift generation is evaluated. A total of 49 flapping experiments were presented, experimental data shows good correlation with the model's prediction. With the wing rotational hinge stiffness designed so that the rotational resonant frequency is twice as the stroke frequency, the resulting wing rotation generates near optimal lift. With further simulation, the proposed model shows low sensitivity to wing parameter variation. As a result, giving a design parameter of a flapping wing robot platform, the proposed principle can

  7. Microelectronics from fundamentals to applied design

    CERN Document Server

    Di Paolo Emilio, Maurizio

    2016-01-01

    This book serves as a practical guide for practicing engineers who need to design analog circuits for microelectronics.  Readers will develop a comprehensive understanding of the basic techniques of analog modern electronic circuit design, discrete and integrated, application as sensors and control and data acquisition systems,and techniques of PCB design.  ·         Describes fundamentals of microelectronics design in an accessible manner; ·         Takes a problem-solving approach to the topic, offering a hands-on guide for practicing engineers; ·         Provides realistic examples to inspire a thorough understanding of system-level issues, before going into the detail of components and devices; ·         Uses a new approach and provides several skills that help engineers and designers retain key and advanced concepts.

  8. Designing for Open Learning: Design Principles and Scalability Affordances in Practice

    OpenAIRE

    Firssova, Olga; Brouns, Francis; Kalz, Marco

    2016-01-01

    This work-in-progress paper elaborates on a gradually evolving approach to design of open learning and the design principles used by the Open University of the Netherlands in short open courses - online masterclasses and in Massive Open Online Courses – delivered in the learning environment of the Open University and in the experimental multilingual MOOC aggregator EMMA as part of a European project. As the paper will demonstrate, these principles can be seen as building blocks of open scalab...

  9. In search of design principles for developing digital learning & performance support for a student design task

    NARCIS (Netherlands)

    Bollen, Lars; Van der Meij, Hans; Leemkuil, Henny; McKenney, Susan

    2016-01-01

    A digital learning and performance support environment for university student design tasks was developed. This paper describes on the design rationale, process, and the usage results to arrive at a core set of design principles for the construction of such an environment. We present a collection of

  10. In search of design principles for developing digital learning & performance support for a student design task

    NARCIS (Netherlands)

    Bollen, Lars; Meij, van der Hans; Leemkuil, Henny; McKenney, Susan

    2015-01-01

    A digital learning and performance support environment for university student design tasks was developed. This paper describes on the design rationale, process, and the usage results to arrive at a core set of design principles for the construction of such an environment. We present a collection of

  11. Design Principles for Serious Video Games in Mathematics Education: From Theory to Practice

    Directory of Open Access Journals (Sweden)

    Konstantinos Chorianopoulos

    2014-09-01

    Full Text Available There is growing interest in the employment of serious video games in science education, but there are no clear design principles. After surveying previous work in serious video game design, we highlighted the following design principles: 1 engage the students with narrative (hero, story, 2 employ familiar gameplay mechanics from popular video games, 3 engage students into constructive trial and error game-play and 4 situate collaborative learning. As illustrated examples we designed two math video games targeted to primary education students. The gameplay of the math video games embeds addition operations in a seamless way, which has been inspired by that of classic platform games. In this way, the students are adding numbers as part of popular gameplay mechanics and as a means to reach the video game objective, rather than as an end in itself. The employment of well-defined principles in the design of math video games should facilitate the evaluation of learning effectiveness by researchers. Moreover, educators can deploy alternative versions of the games in order to engage students with diverse learning styles. For example, some students might be motived and benefited by narrative, while others by collaboration, because it is unlikely that one type of serious video game might fit all learning styles. The proposed principles are not meant to be an exhaustive list, but a starting point for extending the list and applying them in other cases of serious video games beyond mathematics and learning.

  12. Applying AHP to Web Navigation Design

    OpenAIRE

    Su-Hua Wang; Che-Hung Lin

    2008-01-01

    Due to increasing popularity of the World Wide Web, web-based systems are widely used. Most corporate web sites try to enhance their usability by providing artistic web presentations. However, the design of web sites is not judged solely on an artistic basis. Two of the most important design criteria for web sites are access to web content and navigation architecture. This research proposes a platform for automatically evaluating the quality of web navigation architecture. Because of the hier...

  13. Bayesian Design Space applied to Pharmaceutical Development

    OpenAIRE

    Lebrun, Pierre

    2012-01-01

    Given the guidelines such as the Q8 document published by the International Conference on Harmonization (ICH), that describe the “Quality by Design” paradigm for the Pharmaceutical Development, the aim of this work is to provide a complete methodology addressing this problematic. As a result, various Design Spaces were obtained for different analytical methods and a manufacturing process. In Q8, Design Space has been defined as the “the multidimensional combination and interaction of input...

  14. Engineering emergence: applied theory for game design

    OpenAIRE

    Dormans, J.

    2012-01-01

    Dit proefschrift presenteert twee theoretische kaders voor het ontwerpen van games en beschrijft hoe game designers deze kunnen inzetten om het game ontwerpproces te stroomlijnen. Er bestaan op dit moment meerdere ontwerptheorie¨en voor games, maar geen enkele kan rekenen op een breed draagvlak binnen de game industrie. Vooral academische ontwerptheorie¨en hebben regelmatig een slechte reputatie. Het eerste kader dat game designers inzicht biedt in spelregels en hun werking heet Machinations ...

  15. Integrating rock mechanics issues with repository design through design process principles and methodology

    Energy Technology Data Exchange (ETDEWEB)

    Bieniawski, Z.T. [Pennsylvania State Univ., University Park, PA (United States)

    1996-04-01

    A good designer needs not only knowledge for designing (technical know-how that is used to generate alternative design solutions) but also must have knowledge about designing (appropriate principles and systematic methodology to follow). Concepts such as {open_quotes}design for manufacture{close_quotes} or {open_quotes}concurrent engineering{close_quotes} are widely used in the industry. In the field of rock engineering, only limited attention has been paid to the design process because design of structures in rock masses presents unique challenges to the designers as a result of the uncertainties inherent in characterization of geologic media. However, a stage has now been reached where we are be able to sufficiently characterize rock masses for engineering purposes and identify the rock mechanics issues involved but are still lacking engineering design principles and methodology to maximize our design performance. This paper discusses the principles and methodology of the engineering design process directed to integrating site characterization activities with design, construction and performance of an underground repository. Using the latest information from the Yucca Mountain Project on geology, rock mechanics and starter tunnel design, the current lack of integration is pointed out and it is shown how rock mechanics issues can be effectively interwoven with repository design through a systematic design process methodology leading to improved repository performance. In essence, the design process is seen as the use of design principles within an integrating design methodology, leading to innovative problem solving. In particular, a new concept of {open_quotes}Design for Constructibility and Performance{close_quotes} is introduced. This is discussed with respect to ten rock mechanics issues identified for repository design and performance.

  16. Integrating rock mechanics issues with repository design through design process principles and methodology

    International Nuclear Information System (INIS)

    A good designer needs not only knowledge for designing (technical know-how that is used to generate alternative design solutions) but also must have knowledge about designing (appropriate principles and systematic methodology to follow). Concepts such as open-quotes design for manufactureclose quotes or open-quotes concurrent engineeringclose quotes are widely used in the industry. In the field of rock engineering, only limited attention has been paid to the design process because design of structures in rock masses presents unique challenges to the designers as a result of the uncertainties inherent in characterization of geologic media. However, a stage has now been reached where we are be able to sufficiently characterize rock masses for engineering purposes and identify the rock mechanics issues involved but are still lacking engineering design principles and methodology to maximize our design performance. This paper discusses the principles and methodology of the engineering design process directed to integrating site characterization activities with design, construction and performance of an underground repository. Using the latest information from the Yucca Mountain Project on geology, rock mechanics and starter tunnel design, the current lack of integration is pointed out and it is shown how rock mechanics issues can be effectively interwoven with repository design through a systematic design process methodology leading to improved repository performance. In essence, the design process is seen as the use of design principles within an integrating design methodology, leading to innovative problem solving. In particular, a new concept of open-quotes Design for Constructibility and Performanceclose quotes is introduced. This is discussed with respect to ten rock mechanics issues identified for repository design and performance

  17. Proof of principle for epitope-focused vaccine design

    Science.gov (United States)

    Correia, Bruno E.; Bates, John T.; Loomis, Rebecca J.; Baneyx, Gretchen; Carrico, Chris; Jardine, Joseph G.; Rupert, Peter; Correnti, Colin; Kalyuzhniy, Oleksandr; Vittal, Vinayak; Connell, Mary J.; Stevens, Eric; Schroeter, Alexandria; Chen, Man; MacPherson, Skye; Serra, Andreia M.; Adachi, Yumiko; Holmes, Margaret A.; Li, Yuxing; Klevit, Rachel E.; Graham, Barney S.; Wyatt, Richard T.; Baker, David; Strong, Roland K.; Crowe, James E.; Johnson, Philip R.; Schief, William R.

    2014-03-01

    Vaccines prevent infectious disease largely by inducing protective neutralizing antibodies against vulnerable epitopes. Several major pathogens have resisted traditional vaccine development, although vulnerable epitopes targeted by neutralizing antibodies have been identified for several such cases. Hence, new vaccine design methods to induce epitope-specific neutralizing antibodies are needed. Here we show, with a neutralization epitope from respiratory syncytial virus, that computational protein design can generate small, thermally and conformationally stable protein scaffolds that accurately mimic the viral epitope structure and induce potent neutralizing antibodies. These scaffolds represent promising leads for the research and development of a human respiratory syncytial virus vaccine needed to protect infants, young children and the elderly. More generally, the results provide proof of principle for epitope-focused and scaffold-based vaccine design, and encourage the evaluation and further development of these strategies for a variety of other vaccine targets, including antigenically highly variable pathogens such as human immunodeficiency virus and influenza.

  18. Application of Instructional Design Principles in Developing an Online Information Literacy Curriculum.

    Science.gov (United States)

    Mi, Misa

    2016-01-01

    An online information literacy curriculum was developed as an intervention to engage students in independent study and self-assessment of their learning needs and learning outcomes, develop proficiency in information skills, and foster lifelong learning. This column demonstrates how instructional design principles were applied to create the learning experiences integrated into various courses of the medical curriculum to promote active learning of information skills and maximize self-directed learning outcomes for lifelong learning. PMID:26794201

  19. SYSTEMATIC PRINCIPLES AND METHODS OF SYMBOLIC APPROACHES IN URBAN DESIGN

    Directory of Open Access Journals (Sweden)

    BULAKH I. V

    2015-12-01

    Full Text Available Formulation of the problem. The low level of expression and personalization of mass architecture of the second half of the twentieth century connected with the spread of industrial technology and even to a greater extent with mechanistic traditionally functional relation to the average person as, abstract consumer architecture. The condition out of the critical situation is focusing on matters aesthetic, artistic understanding and harmonious image creation environment. The problem of increasing architectural and artistic level of architectural and urban planning solutions to overcome the monotony of planning and development, creating aesthetically expressive urban environment does not lose relevance over the past decades. Understanding and acceptance of enigma and dynamic development of cities encourage architects to find new design techniques that are able to provide in the future a reasonable possibility of forming artistic and aesthetic image of the modern city. Purpose. Define and systematize the principles of symbolization architectural and planning images; propose methods symbolism in the architectural planning of image of the urban environment. Conclusion based on analysis of the enhanced concept symbolizing the image of Architecture and Planning, the place, role and symbolization trends at all levels of the urban environment - planning, three-dimensional and improvement of urban areas; first identified the main stages and levels of symbolization (analohyzatsyya, schematization and alehoryzatsiya, their features and characteristics, formulated the basic principles of symbolization architectural and planning of image, namely the principles of communication between figurative analogies, transformation of subsequent circuits, switching allegorical groupings and metamorfizm ultimate goal – symbol birth .

  20. Implementation of the non-flutter design principle

    DEFF Research Database (Denmark)

    Andersen, Michael Styrk; Sahin, Emrah; Laustsen, Benjamin;

    2014-01-01

    The non-flutter design principle is introduced. Aerodynamically stable section model tests performed by three different research groups indicate, that flutter might be avoided if the torsional-to-vertical frequency ratio is kept below 1. A case study of a suspension bridge spanning 3:7 km with a...... torsional-to-vertical frequency ratio = 0.89 is presented. Using a multimodal flutter approach and bridge deck flutter derivatives equal to those of a thin airfoil, classical flutter was shown not to occur....

  1. Design principles and algorithms for automated air traffic management

    Science.gov (United States)

    Erzberger, Heinz

    1995-01-01

    This paper presents design principles and algorithm for building a real time scheduler. The primary objective of the scheduler is to assign arrival aircraft to a favorable landing runway and schedule them to land at times that minimize delays. A further objective of the scheduler is to allocate delays between high altitude airspace far from the airport and low altitude airspace near the airport. A method of delay allocation is described that minimizes the average operating cost in the presence of errors in controlling aircraft to a specified landing time.

  2. Applying Universal Design for Learning to Instructional Lesson Planning

    Science.gov (United States)

    McGhie-Richmond, Donna; Sung, Andrew N.

    2013-01-01

    Universal Design for Learning is a framework for developing inclusive instructional lesson plans. The effects of introducing Universal Design for Learning Principles and Guidelines in a university teacher education program with pre-service and practicing teachers were explored in a mixed methods approach. The results indicate that the study…

  3. Radiation chemistry applied to drug design

    International Nuclear Information System (INIS)

    Radiation chemistry can contribute to drug design by quantifying redox properties of drugs and where free radicals are suspected intermediates in drug action, radiation can be used to generate these putative species and help characterise relevant reactions. Steady radiolysis produces radicals at a readily-varied but quantified rate; pulse radiolysis with fast spectrophotometric and/or conductimetric detection enables the kinetic properties of radicals to be monitored directly. Using these methods, radical intermediates from drugs with specific cytotoxicity towards hypoxic cells have been shown to react rapidly with oxygen. Radical oxidants from activated neutrophils include superoxide and hydroxyl radicals, and radiation-chemical methods have an important role to play in rational drug design to exploit such oxidative chemistry. Antioxidants can also be evaluated quantitatively by radiolysis methods; the conjugation reactions of thiyl radicals with thiolate and oxygen are now recognised to be major contributions of pulse radiolysis to thiol biochemistry. (author)

  4. Radiation chemistry applied to drug design

    Energy Technology Data Exchange (ETDEWEB)

    Wardman, P.; Candeias, L.P.; Everett, S.A. (Mount Vernon Hospital, Northwood (United Kingdom). Cancer Research Campaign Gray Lab.); Tracy, M. (SRI International, Menlo Park, CA (United States))

    1994-01-01

    Radiation chemistry can contribute to drug design by quantifying redox properties of drugs and where free radicals are suspected intermediates in drug action, radiation can be used to generate these putative species and help characterise relevant reactions. Steady radiolysis produces radicals at a readily-varied but quantified rate; pulse radiolysis with fast spectrophotometric and/or conductimetric detection enables the kinetic properties of radicals to be monitored directly. Using these methods, radical intermediates from drugs with specific cytotoxicity towards hypoxic cells have been shown to react rapidly with oxygen. Radical oxidants from activated neutrophils include superoxide and hydroxyl radicals, and radiation-chemical methods have an important role to play in rational drug design to exploit such oxidative chemistry. Antioxidants can also be evaluated quantitatively by radiolysis methods; the conjugation reactions of thiyl radicals with thiolate and oxygen are now recognised to be major contributions of pulse radiolysis to thiol biochemistry. (author).

  5. Using a holistic life cycle perspective to apply the precautionary principle

    Energy Technology Data Exchange (ETDEWEB)

    Garner, D.; Shiels, S. [British Nuclear Fuels Ltd., Sellafield (United Kingdom)

    2001-07-01

    The precautionary principle places the burden of proof, or justification, on the proponent of an activity. Industry is therefore required to assess and present all scientific information relevant to an activity. This is best achieved when a completely holistic approach is applied to determine the overall environmental impacts associated with an activity. One methodology that can be adopted for this purpose, encompassing all environmental impacts over the complete life cycle acknowledging the principles of BAT, BPEO, ALARP and BPM, is Life Cycle Assessment (LCA). This paper presents a summary of two LCA studies to illustrate the concept of an''environmental optimum'' to assist in the decision making process and to promote sustainable environmental management. (author)

  6. Using a holistic life cycle perspective to apply the precautionary principle

    International Nuclear Information System (INIS)

    The precautionary principle places the burden of proof, or justification, on the proponent of an activity. Industry is therefore required to assess and present all scientific information relevant to an activity. This is best achieved when a completely holistic approach is applied to determine the overall environmental impacts associated with an activity. One methodology that can be adopted for this purpose, encompassing all environmental impacts over the complete life cycle acknowledging the principles of BAT, BPEO, ALARP and BPM, is Life Cycle Assessment (LCA). This paper presents a summary of two LCA studies to illustrate the concept of an''environmental optimum'' to assist in the decision making process and to promote sustainable environmental management. (author)

  7. Engineering emergence: applied theory for game design

    OpenAIRE

    Scha, R.J.H.; Brunekreef, J.J.; Dormans, J.

    2012-01-01

    Joris Dormans ontwikkelde softwaretools om het ontwerpen van games te ondersteunen en naar een hoger plan te tillen. Toegepaste theorie voor game design, zoals Dormans die voorstelt, is er op gericht om creativiteit te ondersteunen, het ontwerpproces te versnellen, en de kwaliteit van games te verhogen. Hierbij spelen twee theoretische kaders een rol. Het eerste kader beschrijft games als systemen van spelregels, waarbij de onderlinge structuur van doorslaggevend belang is in het onvoorspelba...

  8. The Art of Software Design, a Video Game for Learning Software Design Principles

    OpenAIRE

    Stikkolorum, Dave R.; Chaudron, Michel R. V.; de Bruin, Oswald

    2014-01-01

    This paper introduces our gamification of a part of our software design curriculum. Based on typical design principles a motivating learning game is developed to train students in software design. We use Bloom's taxonomy to determine learning objectives. We keep the player engaged with direct feedback in a challenging level based game with increasing complexity. Players can evaluate their design actions with the help of the visualisation of control and data flows. The main learning objective:...

  9. IFE Power Plant design principles. Drivers. Solid state laser drivers

    International Nuclear Information System (INIS)

    The present status of solid state laser drivers for an inertial confinement thermonuclear fusion power plant is discussed. In particular, the feasibility of laser diode pumped solid state laser drivers from both the technical and economic points of view is briefly reviewed. Conceptual design studies showed that they can, in principle, satisfy the design requirements. However, development of new solid state materials with long fluorescence lifetimes and good thermal characteristics is a key issue for laser diode pumped solid state lasers. With the advent of laser diode pumping many materials which were abandoned in the past can presently be reconsidered as viable candidates. It is also concluded that it is important to examine the technical requirements for solid state lasers in relation to target performance criteria. The progress of laser diode pumped lasers in industrial applications should also be closely watched to provide additional information on the economic feasibility of this type of driver. 15 refs, 9 figs, 2 tabs

  10. Five Principles for MOOC Design: With a Case Study

    Directory of Open Access Journals (Sweden)

    John R. Drake

    2015-05-01

    Full Text Available New web technologies have enabled online education to take on a massive scale, prompting many universities to create massively open online courses (MOOCs that take advantage of these technologies in a seemingly effortless manner. Designing a MOOC, however, is anything but trivial. It involves developing content, learning activities, and assessments to accommodate both the massiveness and openness of the course. To design an effective MOOC, instructors need to integrate both pedagogical and information systems theory. In this paper, we present a case study of a MOOC grant and a series of decisions made in its development. These decisions, when paired with the theoretical framework, suggest five principles – meaningful, engaging, measurable, accessible, and scalable – may be applicable to future MOOC development projects.

  11. General principles and stages of optimal AFCS design

    Science.gov (United States)

    Platonov, A.; Zaitsev, Ie.

    2014-11-01

    The goal of the paper is a discussion of general principle and stages of the optimal analog feedback communication systems (AFCS) design. Previous research devoted to the analysis of particularities of AFCS functioning gave necessary analytical basis for transition to practical design of optimal AFCS. This is new class of communication systems (CS) transmitting the signals, under given bit error rate (BER), with bit rate equal to the capacity of the forward channel and power-bandwidth efficiency attaining the theoretical limit. In the paper, we describe the ordered sequence of the stages of transition from the abstract results to designing of the pre-commercial versions of optimal AFCS considering them as the basic communication link "sensor node (SN)" - "base station" (BS) of the wireless sensor network (WSN). We also show that verified theoretical results enable analytically argued decision making at different stages of designing of the high quality and energy efficient WSN communication links. This facilitates optimisation of the project works schedule, distribution of the tasks and resources for their realization, reduce the time and cost of design.

  12. Applying Point Elasticity of Demand Principles to Optimal Pricing in Management Accounting

    Directory of Open Access Journals (Sweden)

    Gareth Wyn Owen

    2012-01-01

    Full Text Available This study applies first principles in micro economics relating to price elasticity of demand to explore a new concept called the price elasticity of contribution to help businesses adopt pricing strategies for the maximisation of contribution. The study derives a new proof for the maximisation of revenue and profit, using the point elasticity of demand equation to simplify the traditional management accounting methodology for algebraically calculating the price at which business revenue and profit are maximised. The study uses one example throughout to demonstrate the proof and to illustrate the concepts introduced.

  13. The ICRP principles applied to radiation protection of the patient in diagnostic radiology

    International Nuclear Information System (INIS)

    The International Commission on Radiation Protection (ICRP) has published new recommendations in Publication 60. These take account of the new biological information and trends in the setting of radiation protection standards since 1977. The main principle for radiation protection of the patient is that the exposure should be justified not only at a broad level but also with respect to the individual patient. Protection arrangements should be optimised using reference dose levels as an upper bound of the optimisation process. The reference levels should be applied with flexibility and based on sound clinical judgement. (authors)

  14. Design Principles for Oxygen Reduction and Evolution on Oxide Catalysts

    Science.gov (United States)

    Shao-Horn, Yang

    2012-02-01

    Driven by growing concerns about global warming and the depletion of petroleum resources, developing renewable energy production and storage technologies represent one of the major scientific challenges of the 21^st century. A critical element in pursuit of this quest is the discovery of efficient and cost-effective catalysts used in solar fuel production via electrochemical energy conversion processes such as oxygen evolution reaction (OER) and oxygen reduction reaction (ORR), both of which are central to the efficiencies of direct-solar and electrolytic water-splitting devices, fuel cells, and metal-air batteries. Although the Sabatier's principle provides a qualitative argument in tuning catalytic activity by varying the bond strength between catalyst surface and reactant/product (neither too strong nor too weak leading to the maximum activity at moderate bond strength), it has no predictive power to find catalysts with enhanced activity. Identifying a ``design principle'' that links catalyst properties to the catalytic activity is critical to accelerate the search for highly active catalysts based on abundant elements, and minimize the use of precious metals. Here we establish a molecular principle that governs the activities of oxygen evolution reaction (OER) and oxygen reduction reaction (ORR) for oxide catalysts, where the activities primarily correlate to the σ* orbital (``eg'') occupation of surface transition-metal cations established by systematic examination of more than ten to fifteen transition-metal oxides. The intrinsic ORR and OER activities exhibit a volcano-shaped dependence on the eg occupancy and the activities peak at an eg occupancy close to unity. Our findings reflect the critical influence of the σ* orbital on the energetics of surface reaction intermediates on surface transition metal ions such as the O2^2-/OH^- displacement and the OH^- regeneration, and thus highlight the importance of surface oxide electronic structure in controlling

  15. Synthetic RNAs for gene regulation: design principles and computational tools

    Directory of Open Access Journals (Sweden)

    Alessandro Laganà

    2014-12-01

    Full Text Available The use of synthetic non-coding RNAs for post-transcriptional regulation of gene expression has not only become a standard laboratory tool for gene functional studies, but it has also opened up new perspectives in the design of new and potentially promising therapeutic strategies. Bioinformatics has provided researchers with a variety of tools for the design, the analysis and the evaluation of RNAi agents such as small-interfering RNA (siRNA, short-hairpin RNA (shRNA, artificial microRNA (a-miR and microRNA sponges. More recently, a new system for genome engineering based on the bacterial CRISPR-Cas9 system (Clustered Regularly Interspaced Short Palindromic Repeats, was shown to have the potential to also regulate gene expression at both transcriptional and post-transcriptional level in a more specific way. In this mini review, we present RNAi and CRISPRi design principles and discuss the advantages and limitations of the current design approaches.

  16. Synthetic RNAs for Gene Regulation: Design Principles and Computational Tools.

    Science.gov (United States)

    Laganà, Alessandro; Shasha, Dennis; Croce, Carlo Maria

    2014-01-01

    The use of synthetic non-coding RNAs for post-transcriptional regulation of gene expression has not only become a standard laboratory tool for gene functional studies but it has also opened up new perspectives in the design of new and potentially promising therapeutic strategies. Bioinformatics has provided researchers with a variety of tools for the design, the analysis, and the evaluation of RNAi agents such as small-interfering RNA (siRNA), short-hairpin RNA (shRNA), artificial microRNA (a-miR), and microRNA sponges. More recently, a new system for genome engineering based on the bacterial CRISPR-Cas9 system (Clustered Regularly Interspaced Short Palindromic Repeats), was shown to have the potential to also regulate gene expression at both transcriptional and post-transcriptional level in a more specific way. In this mini review, we present RNAi and CRISPRi design principles and discuss the advantages and limitations of the current design approaches. PMID:25566532

  17. A cost benefit review of applying quality assurance principles to project management of environmental cleanup programs

    International Nuclear Information System (INIS)

    This paper shows the cost/benefit mechanism used for applying the theory and practical aspects of QA principles as a management tool to project management of environmental cleanup projects. This includes reviewing and guidelines and requirements to determine the practical aspects of applying these requirements to environmental project management. Thus, there is a feedback loop for comparison of the cost/benefits of application of each stage of the project. The project's major stages include planning, environmental sampling, analysis of data samples, data/information management to include reporting, and follow- up, post-cleanup sampling with continued data management. A comparison is also made of the theory with the practical aspects of each of these stages

  18. Parallel power electronics filters in three-phase four-wire systems principle, control and design

    CERN Document Server

    Wong, Man-Chung; Lam, Chi-Seng

    2016-01-01

    This book describes parallel power electronic filters for 3-phase 4-wire systems, focusing on the control, design and system operation. It presents the basics of power-electronics techniques applied in power systems as well as the advanced techniques in controlling, implementing and designing parallel power electronics converters. The power-quality compensation has been achieved using active filters and hybrid filters, and circuit models, control principles and operational practice problems have been verified by principle study, simulation and experimental results. The state-of-the-art research findings were mainly developed by a team at the University of Macau. Offering background information and related novel techniques, this book is a valuable resource for electrical engineers and researchers wanting to work on energy saving using power-quality compensators or renewable energy power electronics systems. .

  19. Design (and) principles of nuclear dynamics in Stockholm.

    Science.gov (United States)

    Shav-Tal, Yaron; Lammerding, Jan

    2015-11-01

    The structural organization of the nucleus and its content has drawn increasing interest in recent years, as it is has become evident that the spatial and temporal arrangement of the genome and associated structures plays a crucial role in transcriptional regulation and numerous other functions. Shining light on the dynamic nature of this organization, along with the processes controlling it, were the topics of the Wenner-Gren Foundations international symposium "Nuclear Dynamics: Design (and) Principles." The meeting, organized by Piorgiogio Percipalle, Maria Vartiainen, Neus Visa, and Ann-Kristin Östlund-Farrants, brought over 60 participants, including 20 international speakers, to Stockholm, Sweden from August 19-22, 2015 to share the latest developments in the field. Given the unpublished nature of many of the talks, we have focused on covering the discussed topics and highlighting the latest trends in this exciting and rapidly evolving field. PMID:26730816

  20. Using the principles of circadian physiology enhances shift schedule design

    International Nuclear Information System (INIS)

    Nuclear power plants must operate 24 h, 7 days a week. For the most part, shift schedules currently in use at nuclear power plants have been designed to meet operational needs without considering the biological clocks of the human operators. The development of schedules that also take circadian principles into account is a positive step that can be taken to improve plant safety by optimizing operator alertness. These schedules reduce the probability of human errors especially during backshifts. In addition, training programs that teach round-the-clock workers how to deal with the problems of shiftwork can help to optimize performance and alertness. These programs teach shiftworkers the underlying causes of the sleep problems associated with shiftwork and also provide coping strategies for improving sleep and dealing with the transition between shifts. When these training programs are coupled with an improved schedule, the problems associated with working round-the-clock can be significantly reduced

  1. Usability principles to design mobile workplace learning content

    Directory of Open Access Journals (Sweden)

    Alessia Messuti

    2015-04-01

    Full Text Available The article describes the design of a mobile workplace learning tool for trainers of the International Training Centre of the International Labour Organization. The motivation behind is to provide trainers with a practical tool that will enable them to recall information at the moment of need and continue to learn in context. On this purpose a set of visual augmented reality cards was created, taking into consideration the fundamental mobile learning and usability principles. The nature of the article is empirical as it reports an experiment carried out with trainers which aimed at testing cards usability and learnability. Results show that the integration of both online and offline strategies was perceived as an added value as trainers could choose to retrieve information as they mostly like; finally, it also resulted in high usability scores, an aspect that contributes to their effectiveness at the workplace.

  2. Using the principles of circadian physiology enhances shift schedule design

    Energy Technology Data Exchange (ETDEWEB)

    Connolly, J.J.; Moore-Ede, M.C.

    1987-01-01

    Nuclear power plants must operate 24 h, 7 days a week. For the most part, shift schedules currently in use at nuclear power plants have been designed to meet operational needs without considering the biological clocks of the human operators. The development of schedules that also take circadian principles into account is a positive step that can be taken to improve plant safety by optimizing operator alertness. These schedules reduce the probability of human errors especially during backshifts. In addition, training programs that teach round-the-clock workers how to deal with the problems of shiftwork can help to optimize performance and alertness. These programs teach shiftworkers the underlying causes of the sleep problems associated with shiftwork and also provide coping strategies for improving sleep and dealing with the transition between shifts. When these training programs are coupled with an improved schedule, the problems associated with working round-the-clock can be significantly reduced.

  3. Carbon-rich icosahedral boron carbide designed from first principles

    Energy Technology Data Exchange (ETDEWEB)

    Jay, Antoine; Vast, Nathalie; Sjakste, Jelena; Duparc, Olivier Hardouin [Ecole Polytechnique, Laboratoire des Solides Irradiés, CEA-DSM-IRAMIS, CNRS UMR 7642, F-91120 Palaiseau (France)

    2014-07-21

    The carbon-rich boron-carbide (B{sub 11}C)C-C has been designed from first principles within the density functional theory. With respect to the most common boron carbide at 20% carbon concentration B{sub 4}C, the structural modification consists in removing boron atoms from the chains linking (B{sub 11}C) icosahedra. With C-C instead of C-B-C chains, the formation of vacancies is shown to be hindered, leading to enhanced mechanical strength with respect to B{sub 4}C. The phonon frequencies and elastic constants turn out to prove the stability of the carbon-rich phase, and important fingerprints for its characterization have been identified.

  4. Temporal Evolution of Design Principles in Engineering Systems: Analogies with Human Evolution

    DEFF Research Database (Denmark)

    Deb, Kalyanmoy; Bandaru, Sunith; Tutum, Cem Celal

    2012-01-01

    constructed later during optimization. Interestingly, there exists a simile between evolution of design principles with that of human evolution. Such information about the hierarchy of key design principles should enable designers to have a deeper understanding of their problems....... among near-Paretooptimal solutions, the main crux of this paper lies in a demonstration of temporal evolution of these principles during the course of optimization. The results reveal that certain important design principles start to evolve early on, whereas some detailed design principles get...

  5. Applying persuasive design in a diabetes mellitus application

    NARCIS (Netherlands)

    Smink, Sjoerd

    2012-01-01

    This paper describes persuasive design methods and compares this to an application currently under development for diabetes mellitus patients. Various elements of persuasion and a categorization of persuasion types are mentioned. Also discussed are principles of how successful persuasion should be d

  6. Coalescence vs. concatenation: Sophisticated analyses vs. first principles applied to rooting the angiosperms.

    Science.gov (United States)

    Simmons, Mark P; Gatesy, John

    2015-10-01

    It has recently been concluded that phylogenomic data from 310 nuclear genes support the clade of (Amborellales, Nymphaeales) as sister to the remaining angiosperms and that shortcut coalescent phylogenetic methods outperformed concatenation for these data. We falsify both of those conclusions here by demonstrating that discrepant results between the coalescent and concatenation analyses are primarily caused by the coalescent methods applied (MP-EST and STAR) not being robust to the highly divergent and often mis-rooted gene trees that were used. This result reinforces the expectation that low amounts of phylogenetic signal and methodological artifacts in gene-tree reconstruction can be more problematic for shortcut coalescent methods than is the assumption of a single hierarchy for all genes by concatenation methods when these approaches are applied to ancient divergences in empirical studies. We also demonstrate that a third coalescent method, ASTRAL, is more robust to mis-rooted gene trees than MP-EST or STAR, and that both Observed Variability (OV) and Tree Independent Generation of Evolutionary Rates (TIGER), which are two character subsampling procedures, are biased in favor of characters with highly asymmetrical distributions of character states when applied to this dataset. We conclude that enthusiastic application of novel tools is not a substitute for rigorous application of first principles, and that trending methods (e.g., shortcut coalescent methods applied to ancient divergences, tree-independent character subsampling), may be novel sources of previously under-appreciated, systematic errors. PMID:26002829

  7. Silver Nanoclusters: From Design Principles to Practical Applications

    KAUST Repository

    Abdulhalim, Lina G.

    2015-12-08

    A strategy based on reticulating metal ions and organic ligands into atomically precise gold and silver nanoclusters (NCs) with high monodispersity has been advanced to a point that allows the design of NCs with strict stoichiometries, functionalities and valence. Of the Ag NCs discovered, Ag44 is the most studied, not only due to its high absorption that transcends the visible spectrum suitable for photovoltaics but also because of its long excited state lifetime, as revealed by nanosecond transient absorption spectroscopy. A major principle discovered in this dissertation is the ability to produce Ag44 in scalable amounts and with high stability in addition to modulation of the functional groups of the organic ligands via a fast and complete ligand exchange process. This new discovery has led to the development of synthetic designs in which new sizes were obtained by varying the reaction parameters (e.g., ligands functionality, reaction temperature and time), namely, Ag29 using dithiols and phosphines. The synthesized NCs possess tetravalent functionalities that facilitate their crystallization and characterization. Furthermore, Ag29 glows red and is therefore a possible candidate for sensing and imaging applications.

  8. Conceptual design principles for the MHD-induction generator

    International Nuclear Information System (INIS)

    Conceptual design of the MHD-Induction generator using the exhaust plasma from the fusion reactor divertor as the working fluid and the principles of induction by transformer action is considered in this work. Exciting magnetic field is provided by a set of multi-conductors sheet carrying time varying sinusoidal current. Spacing of line conductors is discrete and arranged such that alternation of boundary layer separation will occur at the generator channel wall, provided the magnetic Reynolds number will exceed 10% as had been already established in published carried out by the 2nd, author. An output three phase conventional winding will carry the induced output voltage by transformer action. Solutions of the induced field identified as odd triangular time varying waves are expanded through Fourier Theorm into its fundamental and a large set of odd harmonics. For the ultimate aim of securing pure sinusoidal output, detailed conceptual design for the conventional winding is carried out, especially for an optimum winding pitch factor. Selection of winding pitch factor of 83.5% resulted in significant reduction in the 5th, the 7th and the eleventh harmonics by 1%, 0.5% and 0.04% of the fundamental strength. Solutions are obtained up to the 65th harmonic to ensure reliable information regarding minimization of their strength

  9. Design principles for engaging and retaining virtual citizen scientists.

    Science.gov (United States)

    Wald, Dara M; Longo, Justin; Dobell, A R

    2016-06-01

    Citizen science initiatives encourage volunteer participants to collect and interpret data and contribute to formal scientific projects. The growth of virtual citizen science (VCS), facilitated through websites and mobile applications since the mid-2000s, has been driven by a combination of software innovations and mobile technologies, growing scientific data flows without commensurate increases in resources to handle them, and the desire of internet-connected participants to contribute to collective outputs. However, the increasing availability of internet-based activities requires individual VCS projects to compete for the attention of volunteers and promote their long-term retention. We examined program and platform design principles that might allow VCS initiatives to compete more effectively for volunteers, increase productivity of project participants, and retain contributors over time. We surveyed key personnel engaged in managing a sample of VCS projects to identify the principles and practices they pursued for these purposes and led a team in a heuristic evaluation of volunteer engagement, website or application usability, and participant retention. We received 40 completed survey responses (33% response rate) and completed a heuristic evaluation of 20 VCS program sites. The majority of the VCS programs focused on scientific outcomes, whereas the educational and social benefits of program participation, variables that are consistently ranked as important for volunteer engagement and retention, were incidental. Evaluators indicated usability, across most of the VCS program sites, was higher and less variable than the ratings for participant engagement and retention. In the context of growing competition for the attention of internet volunteers, increased attention to the motivations of virtual citizen scientists may help VCS programs sustain the necessary engagement and retention of their volunteers. PMID:26365126

  10. Does the principle of minimum work apply at the carotid bifurcation: a retrospective cohort study

    International Nuclear Information System (INIS)

    There is recent interest in the role of carotid bifurcation anatomy, geometry and hemodynamic factors in the pathogenesis of carotid artery atherosclerosis. Certain anatomical and geometric configurations at the carotid bifurcation have been linked to disturbed flow. It has been proposed that vascular dimensions are selected to minimize energy required to maintain blood flow, and that this occurs when an exponent of 3 relates the radii of parent and daughter arteries. We evaluate whether the dimensions of bifurcation of the extracranial carotid artery follow this principle of minimum work. This study involved subjects who had computed tomographic angiography (CTA) at our institution between 2006 and 2007. Radii of the common, internal and external carotid arteries were determined. The exponent was determined for individual bifurcations using numerical methods and for the sample using nonlinear regression. Mean age for 45 participants was 56.9 ± 16.5 years with 26 males. Prevalence of vascular risk factors was: hypertension-48%, smoking-23%, diabetes-16.7%, hyperlipidemia-51%, ischemic heart disease-18.7%. The value of the exponent ranged from 1.3 to 1.6, depending on estimation methodology. The principle of minimum work (defined by an exponent of 3) may not apply at the carotid bifurcation. Additional factors may play a role in the relationship between the radii of the parent and daughter vessels

  11. A practical guide to applying lean tools and management principles to health care improvement projects.

    Science.gov (United States)

    Simon, Ross W; Canacari, Elena G

    2012-01-01

    Manufacturing organizations have used Lean management principles for years to help eliminate waste, streamline processes, and cut costs. This pragmatic approach to structured problem solving can be applied to health care process improvement projects. Health care leaders can use a step-by-step approach to document processes and then identify problems and opportunities for improvement using a value stream process map. Leaders can help a team identify problems and root causes and consider additional problems associated with methods, materials, manpower, machinery, and the environment by using a cause-and-effect diagram. The team then can organize the problems identified into logical groups and prioritize the groups by impact and difficulty. Leaders must manage action items carefully to instill a sense of accountability in those tasked to complete the work. Finally, the team leaders must ensure that a plan is in place to hold the gains. PMID:22201573

  12. Applying object technology principles to business reengineering in the oil, gas, and petrochemical industries

    International Nuclear Information System (INIS)

    The oil, gas, and petrochemical industries face a dilemma, to be financially competitive while complying with strict and expanding environmental, safety, and health regulation. Companies need new tools and techniques, indeed a completely new paradigm for organizing and performing work. They must build efficient and flexible business processes, ones that rely on advanced information systems for improved decision making and productivity. And they must adopt a culture of change and improvement to permit the business to change as the business climate changes. Fortunately, two industry developments are changing the traditional business paradigm in a dramatic way; business reengineering and object technology. Applying principles of object technology in the performance of business reengineering makes available a new form of business modeling that transforms the technique of modeling a business while directly supported the development of its enabling information systems. This modeling technique is called Object Modeling and is becoming an important force in improving business competitiveness

  13. Development and characterization of a cell culture manufacturing process using quality by design (QbD) principles.

    Science.gov (United States)

    Marasco, Daniel M; Gao, Jinxin; Griffiths, Kristi; Froggatt, Christopher; Wang, Tongtong; Wei, Gan

    2014-01-01

    The principles of quality by design (QbD) have been applied in cell culture manufacturing process development and characterization in the biotech industry. Here we share our approach and practice in developing and characterizing a cell culture manufacturing process using QbD principles for establishing a process control strategy. Process development and characterization start with critical quality attribute identification, followed by process parameter and incoming raw material risk assessment, design of experiment, and process parameter classification, and conclude with a design space construction. Finally, a rational process control strategy is established and documented. PMID:23828505

  14. Effective Principles In Designing E-Course In Light Of Learning Theories

    OpenAIRE

    AFIFI, Muhammad K.; Saad S. ALAMRI

    2014-01-01

    The researchers conducted an exploratory study to determine the design quality of some E-courses delivered via the web to a number of colleagues at the university. Results revealed a number of shortcomings in the design of these courses, mostly due to the absence of effective principles in the design of these E-courses, especially principles of pedagogy in relation to learning theories. So, this study seeks to identify effective principles in the design of courses for internet-based learn...

  15. Human Factors Principles in Design of Computer-Mediated Visualization for Robot Missions

    Energy Technology Data Exchange (ETDEWEB)

    David I Gertman; David J Bruemmer

    2008-12-01

    With increased use of robots as a resource in missions supporting countermine, improvised explosive devices (IEDs), and chemical, biological, radiological nuclear and conventional explosives (CBRNE), fully understanding the best means by which to complement the human operator’s underlying perceptual and cognitive processes could not be more important. Consistent with control and display integration practices in many other high technology computer-supported applications, current robotic design practices rely highly upon static guidelines and design heuristics that reflect the expertise and experience of the individual designer. In order to use what we know about human factors (HF) to drive human robot interaction (HRI) design, this paper reviews underlying human perception and cognition principles and shows how they were applied to a threat detection domain.

  16. Designing nanomaterials to maximize performance and minimize undesirable implications guided by the Principles of Green Chemistry.

    Science.gov (United States)

    Gilbertson, Leanne M; Zimmerman, Julie B; Plata, Desiree L; Hutchison, James E; Anastas, Paul T

    2015-08-21

    The Twelve Principles of Green Chemistry were first published in 1998 and provide a framework that has been adopted not only by chemists, but also by design practitioners and decision-makers (e.g., materials scientists and regulators). The development of the Principles was initially motivated by the need to address decades of unintended environmental pollution and human health impacts from the production and use of hazardous chemicals. Yet, for over a decade now, the Principles have been applied to the synthesis and production of engineered nanomaterials (ENMs) and the products they enable. While the combined efforts of the global scientific community have led to promising advances in the field of nanotechnology, there remain significant research gaps and the opportunity to leverage the potential global economic, societal and environmental benefits of ENMs safely and sustainably. As such, this tutorial review benchmarks the successes to date and identifies critical research gaps to be considered as future opportunities for the community to address. A sustainable material design framework is proposed that emphasizes the importance of establishing structure-property-function (SPF) and structure-property-hazard (SPH) relationships to guide the rational design of ENMs. The goal is to achieve or exceed the functional performance of current materials and the technologies they enable, while minimizing inherent hazard to avoid risk to human health and the environment at all stages of the life cycle. PMID:25955514

  17. Featuring dental education research: applying the principles of action research to improve teaching of dental prosthetics.

    Science.gov (United States)

    Khan, S B

    2009-11-01

    This article focuses on educational research conducted at the newly merged UWC faculty of dentistry. The research emphasises the change in teaching methods employed to address the concerns experienced in teaching the new large classes as observed in the prosthetic techniques module. These educational interventions were conducted over 5 years and the study design included the principles of action research. Students were assisted in learning the theory of the practical procedures and the subsequent completion of these procedures with the accurate application of the theoretical concepts. Changes in the teaching methods enhanced students learning and successful translation of the theory into practical work. The active learning exercises incorporated into the teaching further motivated and assisted students with deep learning. The debates indicated that students know and accept the value of the module as part of their training. PMID:20306872

  18. Design Principles and Algorithms for Air Traffic Arrival Scheduling

    Science.gov (United States)

    Erzberger, Heinz; Itoh, Eri

    2014-01-01

    This report presents design principles and algorithms for building a real-time scheduler of arrival aircraft based on a first-come-first-served (FCFS) scheduling protocol. The algorithms provide the conceptual and computational foundation for the Traffic Management Advisor (TMA) of the Center/terminal radar approach control facilities (TRACON) automation system, which comprises a set of decision support tools for managing arrival traffic at major airports in the United States. The primary objective of the scheduler is to assign arrival aircraft to a favorable landing runway and schedule them to land at times that minimize delays. A further objective of the scheduler is to allocate delays between high-altitude airspace far away from the airport and low-altitude airspace near the airport. A method of delay allocation is described that minimizes the average operating cost in the presence of errors in controlling aircraft to a specified landing time. This report is a revision of an earlier paper first presented as part of an Advisory Group for Aerospace Research and Development (AGARD) lecture series in September 1995. The authors, during vigorous discussions over the details of this paper, felt it was important to the air-trafficmanagement (ATM) community to revise and extend the original 1995 paper, providing more detail and clarity and thereby allowing future researchers to understand this foundational work as the basis for the TMA's scheduling algorithms.

  19. Embodied Language Learning and Cognitive Bootstrapping: Methods and Design Principles

    Directory of Open Access Journals (Sweden)

    Caroline Lyon

    2016-05-01

    Full Text Available Co-development of action, conceptualization and social interaction mutually scaffold and support each other within a virtuous feedback cycle in the development of human language in children. Within this framework, the purpose of this article is to bring together diverse but complementary accounts of research methods that jointly contribute to our understanding of cognitive development and in particular, language acquisition in robots. Thus, we include research pertaining to developmental robotics, cognitive science, psychology, linguistics and neuroscience, as well as practical computer science and engineering. The different studies are not at this stage all connected into a cohesive whole; rather, they are presented to illuminate the need for multiple different approaches that complement each other in the pursuit of understanding cognitive development in robots. Extensive experiments involving the humanoid robot iCub are reported, while human learning relevant to developmental robotics has also contributed useful results. Disparate approaches are brought together via common underlying design principles. Without claiming to model human language acquisition directly, we are nonetheless inspired by analogous development in humans and consequently, our investigations include the parallel co-development of action, conceptualization and social interaction. Though these different approaches need to ultimately be integrated into a coherent, unified body of knowledge, progress is currently also being made by pursuing individual methods.

  20. Design principles of liquid nebulization devices currently in use.

    Science.gov (United States)

    Rau, Joseph L

    2002-11-01

    Liquid nebulization is a common method of medical aerosol generation. Nebulizers are of 2 types: jet (or pneumatic) small-volume nebulizer, and ultrasonic nebulizer. Jet nebulizers are based on the venturi principle, whereas ultrasonic nebulizers use the converse piezoelectric effect to convert alternating current to high-frequency acoustic energy. Important variables for both types of nebulizer are treatment time required, particle size produced, and aerosol drug output. There are several advantages to jet nebulization, including that effective use requires only simple, tidal breathing, and that dose modification and dose compounding are possible. Disadvantages include the length of treatment time and equipment size. Design modifications to the constant-output nebulizer have resulted in breath-enhanced, open-vent nebulizers such as the Pari LC Plus and the dosimetric AeroEclipse. Ultrasonic nebulizers generally have a higher output rate than jet nebulizers, but a larger average particle size. Ultrasonic nebulizers can also substantially increase reservoir solution temperature, the opposite of jet nebulizer cooling. Drug concentration in the reservoir does not increase with ultrasonic nebulization, as it does with jet nebulization. Ultrasonic nebulizers have the same advantages as jet nebulizers. Ultrasonic nebulizers are more expensive and fragile than jet nebulizers, may cause drug degradation, and do not nebulize suspensions well. Neither type of nebulizer meets the criteria for an ideal inhaler: efficient and quick dose delivery with reproducibility, cost-effectiveness, and no ambient contamination by lost aerosol. PMID:12425742

  1. Laser beam riding guided system principle and design research

    Science.gov (United States)

    Qu, Zhou; Jin, Yi; Xu, Zhou; Xing, Hao

    2016-01-01

    With the development of science and technology, precision-strike weapons has been considered to be important for winning victory in military field. Laser guidance is a major method to execute precision-strike in modern warfare. At present, the problems of primary stage of Laser guidance has been solved with endeavors of countries. Several technical aspects of laser-beam riding guided system have been mature, such as atmosphere penetration of laser beam, clutter inhibition on ground, laser irradiator, encoding and decoding of laser beam. Further, laser beam quality, equal output power and atmospheric transmission properties are qualified for warfare situation. Riding guidance instrument is a crucial element of Laser-beam riding guided system, and is also a vital element of airborne, vehicle-mounted and individual weapon. The optical system mainly consist of sighting module and laser-beam guided module. Photoelectric detector is the most important sensing device of seeker, and also the key to acquire the coordinate information of target space. Currently, in consideration of the 1.06 u m of wavelength applied in all the semi-active laser guided weapons systems, lithium drifting silicon photodiode which is sensitive to 1.06 u m of wavelength is used in photoelectric detector. Compared to Solid and gas laser, diode laser has many merits such as small volume, simple construction, light weight, long life, low lost and easy modulation. This article introduced the composition and operating principle of Laser-beam riding guided system based on 980 nm diode laser, and made a analysis of key technology; for instance, laser irradiator, modulating disk of component, laser zooming system. Through the use of laser diode, Laser-beam riding guided system is likely to have smaller shape and very light.

  2. Transformer design principles with applications to core-form power transformers

    CERN Document Server

    Del Vecchio, Robert M; Feeney, Mary-Ellen F

    2001-01-01

    Transformer Design Principles presents the theory of transformer operation and the methods and techniques of designing them. It emphasizes the physical principles and mathematical tools for simulating transformer behavior, including modern computer techniques. The scope of the book includes types of construction, circuit analysis, mechanical aspects of design, high voltage insulation requirements, and cooling design. The authors also address test procedures and reliability methods to assure successful design and discuss the economic analysis of designs. Summarizing material currently scattered

  3. HEURISTIC OPTIMIZATION AND ALGORITHM TUNING APPLIED TO SORPTIVE BARRIER DESIGN

    Science.gov (United States)

    While heuristic optimization is applied in environmental applications, ad-hoc algorithm configuration is typical. We use a multi-layer sorptive barrier design problem as a benchmark for an algorithm-tuning procedure, as applied to three heuristics (genetic algorithms, simulated ...

  4. Effective Principles in Designing E-Course in Light of Learning Theories

    Science.gov (United States)

    Afifi, Muhammad K.; Alamri, Saad S.

    2014-01-01

    The researchers conducted an exploratory study to determine the design quality of some E-courses delivered via the web to a number of colleagues at the university. Results revealed a number of shortcomings in the design of these courses, mostly due to the absence of effective principles in the design of these E-courses, especially principles of…

  5. Applications of Context-Aware Computing in Hospital Work - Examples and Design Principles

    DEFF Research Database (Denmark)

    Bardram, Jacob Eyvind

    -aware computing. We present the design of a context-aware pill container and a context-aware hospital bed, both of which reacts and adapts according to what is happening in their context. The applications have been evaluated in a number of workshop with clinicians and patients. Based on this empirical work of......Context-awareness is a key concept in ubiquitous computing, which sometimes seems to be a technology looking for a purpose. In this paper we report on the application of context-aware computing for medical work in hospitals, which has appeared to be a strong case for applying context...... designing, developing, and evaluating context-aware clinical applications, the paper outlines some key design principles for a context-awareness framework, supporting the development and deployment of context-aware clinical computer applications....

  6. Applying Delphi method for strategic design of social entrepreneurship

    OpenAIRE

    Κάβουρα, Ανδρονίκη; Andersson, Tuula; Kavoura, Androniki

    2016-01-01

    This paper aims to examine the strategic design for entrepreneurial activity. This study examines and evaluates a qualitative Delphi methodology used in a research for the strategy development needs of entrepreneurship counselling and education. The strategic design presented may well apply to non-profit organisations due to the fact that limited resources in funding of non-profit organisations exist. Design/methodology/approach – This paper introduces methodological considerations of applyin...

  7. Oscillating system design applying universal formula for control

    OpenAIRE

    Efimov, Denis; Perruquetti, Wilfrid

    2011-01-01

    The problem of oscillating system design applying the homogeneity approach is studied. The Anti-control Lyapunov Function (ALF) is introduced as a counterpart of Control Lyapunov Function (CLF) for the control design that destabilizes a nonlinear system. A universal anti-control formula is proposed. Next, the universal control formulas based on ALF and CLF are used to design an oscillating system. Efficiency of the proposed approach is demonstrated on example.

  8. Engineering Design of an Adaptive Leg Prosthesis Using Biological Principles

    DEFF Research Database (Denmark)

    Lenau, Torben Anker; Dentel, Andy; Invarsdottir, Thorunn;

    2010-01-01

    The biomimetic design process is explored through a design case: An adaptive leg prosthesis. The aim is to investigate if the biomimetic design process can be carried out with a minimum of biological knowledge and without using advanced design methods. In the design case biomimetic design was...

  9. Seismic design and performance of nuclear safety related RC structures based on new seismic design principle

    International Nuclear Information System (INIS)

    Full text: Seismic design of safety related Reinforced Concrete (RC) structures of Nuclear power plants (NPP) in India as per the present AERB codal procedures tries to ensure predominantly elastic behaviour under OBE so that the features of Nuclear Power Plant (NPP) necessary for continued safe operation are designed to remain functional and prevent accident (collapse) of NPP under SSE for which certain Structures, Systems and Components (SSCs) those are necessary to ensure the capability to shut down the reactor safely, are designed to remain functional. While the seismic design principles of non safety related structures as per Indian code (IS 1893-2002) are ensuring elastic behaviour under DBE and inelastic behaviour under MCE by utilizing ductility and energy dissipation capacity of the structure effectively. The design principle of AERB code is ensuring elastic behaviour under OBE and is not enlightening much inference about the overall structural behaviour under SSE (only ensuring the capability of certain SSCs required for safe shutdown of reactor). Various buildings and structures of Indian Nuclear power plant are classified from the basis of associated safety functions in a descending order in according with their roles in preventions and mitigation of an accident or support functions for prevention. This paper covers a comprehensive seismic analysis and design methodology based on the AERB codal provisions followed for safety related RC structure taking Diesel Generator Building of PFBR as a case study and study and investigates its performance under OBE and SSE by carrying out Non-linear static Pushover analysis. Based on the analysis, observed variations, recommendations are given for getting the desired performance level so as to implement performance based design in the future NPP design

  10. Principles and Practices for Teaching English as an International Language. ESL & Applied Linguistics Professional Series

    Science.gov (United States)

    Allsagoff, Lubna, Ed.; McKay, Sandra Lee, Ed.; Hu, Guangwei, Ed.; Renandya, Willy A., Ed.

    2012-01-01

    What general principles should inform a socioculturally sensitive pedagogy for teaching English as an International Language and what practices would be consistent with these principles? This text explores the pedagogical implications of the continuing spread of English and its role as an international language, highlighting the importance of…

  11. Applying axiomatic design methodology in developing modified libertation products

    Directory of Open Access Journals (Sweden)

    Bibiana Margarita Vallejo Díaz

    2010-04-01

    Full Text Available Some conceptual elements regarding the axiomatic design method were applied to a specific case-study regarding developing modified liberation compressed product (CLM-UN, for use in the agricultural sector as pH regulating agent in solil. The study was orientated towards defining functional requeriments, design parameters and process variables for manufacturing the product. Independence and information were evaluated, supporting axiomatic design as an alternative for integral product and process design (as a rational and systemic exercise, facilitating producing products having the quality which future users expect from them.

  12. A game plan: Gamification design principles in mHealth applications for chronic disease management.

    Science.gov (United States)

    Miller, Aaron S; Cafazzo, Joseph A; Seto, Emily

    2016-06-01

    Effective chronic disease management is essential to improve positive health outcomes, and incentive strategies are useful in promoting self-care with longevity. Gamification, applied with mHealth (mobile health) applications, has the potential to better facilitate patient self-management. This review article addresses a knowledge gap around the effective use of gamification design principles, or mechanics, in developing mHealth applications. Badges, leaderboards, points and levels, challenges and quests, social engagement loops, and onboarding are mechanics that comprise gamification. These mechanics are defined and explained from a design and development perspective. Health and fitness applications with gamification mechanics include: bant which uses points, levels, and social engagement, mySugr which uses challenges and quests, RunKeeper which uses leaderboards as well as social engagement loops and onboarding, Fitocracy which uses badges, and Mango Health, which uses points and levels. Specific design considerations are explored, an example of the efficacy of a gamified mHealth implementation in facilitating improved self-management is provided, limitations to this work are discussed, a link between the principles of gaming and gamification in health and wellness technologies is provided, and suggestions for future work are made. We conclude that gamification could be leveraged in developing applications with the potential to better facilitate self-management in persons with chronic conditions. PMID:24986104

  13. 10 CFR 433.6 - Sustainable principles for siting, design and construction. [Reserved

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Sustainable principles for siting, design and construction. 433.6 Section 433.6 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY STANDARDS FOR THE DESIGN AND CONSTRUCTION OF NEW FEDERAL COMMERCIAL AND MULTI-FAMILY HIGH-RISE RESIDENTIAL BUILDINGS § 433.6 Sustainable principles for...

  14. Integrating Quality Matters into Hybrid Course Design: A Principles of Marketing Case Study

    Science.gov (United States)

    Young, Mark R.

    2014-01-01

    Previous research supports the idea that the success of hybrid or online delivery modes is more a function of course design than delivery media. This article describes a case study of a hybrid Principles of Marketing course that implemented a comprehensive redesign based on design principles espoused by the Quality Matters Program, a center for…

  15. Design Principles for Serious Video Games in Mathematics Education: From Theory to Practice

    OpenAIRE

    Konstantinos Chorianopoulos; Michail Giannakos

    2014-01-01

    There is growing interest in the employment of serious video games in science education, but there are no clear design principles. After surveying previous work in serious video game design, we highlighted the following design principles: 1) engage the students with narrative (hero, story), 2) employ familiar gameplay mechanics from popular video games, 3) engage students into constructive trial and error game-play and 4) situate collaborative learning. As illustrated examples we designed two...

  16. Universal Design in Postsecondary Education: Process, Principles, and Applications

    Science.gov (United States)

    Burgstahler, Sheryl

    2009-01-01

    Designing any product or environment involves the consideration of many factors, including aesthetics, engineering options, environmental issues, safety concerns, industry standards, and cost. Typically, designers focus their attention on the average user. In contrast, universal design (UD), according to the Center for Universal Design, "is the…

  17. Content Analysis and Readibility Formulas as Applied To The Accounting Principles Board "Opinions"

    Science.gov (United States)

    Stead, Bette Ann

    1977-01-01

    Discusses a study analyzing twenty-four of the Accounting Principles Board "Opinions" (APB Opinions) and concludes that the APB context is very difficult to read and understand for both accounting and nonaccounting majors. (MH)

  18. Culture change in infection control: applying psychological principles to improve hand hygiene.

    Science.gov (United States)

    Cumbler, Ethan; Castillo, Leilani; Satorie, Laura; Ford, Deborah; Hagman, Jan; Hodge, Therese; Price, Lisa; Wald, Heidi

    2013-01-01

    Hand hygiene occurs at the intersection of habit and culture. Psychological and social principles, including operant conditioning and peer pressure of conforming social norms, facilitate behavior change. Participatory leadership and level hierarchies are needed for sustainable patient safety culture. Application of these principles progressively and significantly improved hand hygiene compared with the hospital aggregate control. Changes to hand hygiene auditing and response processes demonstrate ability to improve and sustain adherence rates within a clinical microsystem. PMID:23669615

  19. Agile Principles Applied to a Complex Long Term Research Activity - The PERIMETER Approach

    OpenAIRE

    Dillon, Eileen; Sivrikaya, Fikret; Haemmerle, Christian; Salgarelli, Luca

    2009-01-01

    Agile software development is a group of software development methodologies that are based on similar principles, as defined in the Agile Manifesto. Agile software projects are characterized by iterative and incremental development, accommodation of changes and active customer participation. The popularity of agile principles is steadily increasing. Their adopters report that this development process leads to higher software quality and customer satisfaction ratings when compared to using ...

  20. How the Principle of Risk Management Can Be Applied to Different Types of Projects?

    OpenAIRE

    Yuanyuan Zhang

    2009-01-01

    Project risk management is a process which combines the analysis and management of the risks with a project and the principles of risk management include two key points which are risk analysis and risk control and arrangement. The case studies clarify the principles of project risk management can be used in different types of projects, and also when doing risk management it should be followed by right steps, choosing the right analysis methods, quantifying the risks precisely and formulating ...

  1. Natural Stone Waste Powders Applied to SCC Mix Design

    NARCIS (Netherlands)

    Hunger, M.; Brouwers, H.J.H.

    2008-01-01

    In order to comply with current trends concerning sustainability, saving of primary materials and energy savings, this paper addresses Eco-concrete. The major focus thereby is on the increased efficiency of cement use. Applying a new mix design method for concrete, cement contents can be decreased a

  2. Bionic Concept Applied to Flow Slab Design of PEMFC

    Science.gov (United States)

    Wang, C. T.; Chang, C. P.

    A character of fuel cell with high potency and low pollution was known well and considered as a new generation of power technology. In this study a novel design of flow slab addressed and originated from bionic concept will be applied to improve the performance of PEMFC. Simulation results executed at Re = 100 show that the bionic flow type will possess a better uniformity of velocity and lower pressure drop. Besides, the integral performance concerned at SDR and PDR will also show the bionic flow type to be an outstanding design. Hence, this novel flow design addressed will be useful to promotion of PEMFC.

  3. Design principles for rapid folding of knotted DNA nanostructures

    OpenAIRE

    Kočar, Vid; Schreck, John S.; Čeru, Slavko; Gradišar, Helena; Bašić, Nino; Pisanski, Tomaž; Doye, Jonathan P. K.; Jerala, Roman

    2016-01-01

    Knots are some of the most remarkable topological features in nature. Self-assembly of knotted polymers without breaking or forming covalent bonds is challenging, as the chain needs to be threaded through previously formed loops in an exactly defined order. Here we describe principles to guide the folding of highly knotted single-chain DNA nanostructures as demonstrated on a nano-sized square pyramid. Folding of knots is encoded by the arrangement of modules of different stability based on de...

  4. Design principles for rapid folding of knotted DNA nanostructures.

    OpenAIRE

    Kočar, V; Schreck, JS; Čeru, S; Gradišar, H; Bašić, N; Pisanski, T; Doye, JP; Jerala, R. (Roman)

    2016-01-01

    Knots are some of the most remarkable topological features in nature. Self-assembly of knotted polymers without breaking or forming covalent bonds is challenging, as the chain needs to be threaded through previously formed loops in an exactly defined order. Here we describe principles to guide the folding of highly knotted single-chain DNA nanostructures as demonstrated on a nano-sized square pyramid. Folding of knots is encoded by the arrangement of modules of different stability based on de...

  5. Comparison of optimization techniques applied to nuclear fuel reload design

    International Nuclear Information System (INIS)

    In this work a comparison of three techniques of optimization is presented applied to the design of the recharge of fuel in reactors of water in boil. In short, the techniques were applied to the design of a recharge of a cycle of balance of 18 months of the Laguna Verde Nucleo electric Central. The used techniques were Genetic Algorithms, Taboo Search and Neural Nets. The conditions to apply the different techniques were the same ones. The comparison of the results quality and the computational resources required to obtain them, it indicates that with the Taboo Search better results are achieved but the computational cost is very big. On the other hand the neural net with low computational cost obtains acceptable results. Additionally to this comparison, in this work a summary of the works that have been carried out for the fuel recharges optimization from the years 60 until the present time is presented. (Author)

  6. Design Principle of A Small Angle Neutron Scattering Spectrometer. Vol. 2

    International Nuclear Information System (INIS)

    The design principle of a small angle neutron scattering (SANS) spectrometer is based on producing monochromatic neutron bursts using two phased rotors. The rotors have a number of slots to achieve the highly available intensity of monoenergetic neutrons at the required resolution. The design principle was applied to improve the performance of the pulsed monochromatic double rotor system at ET-RR-1 to operate as SANS spectrometer. It is shown that for rotors having 19 slots each with radius of curvature 96.8 cm, the intensity gain factor is 13. The proposed SANS spectrometer could cover the neutron wavelength range from 2 Aο up to 6 Aο through small angles of scattering from 5 x 10-3 rad. to 0.1 rad. i.e, the scattering wavevector transfer between 0.6 Aο-1 and 0.01 Aο-1. The maximum neutron flux density on the specimen is 5 x 105 n cm-2 s-1. 8 figs

  7. Graphical symbols -- Safety colours and safety signs -- Part 1: Design principles for safety signs in workplaces and public areas

    CERN Document Server

    International Organization for Standardization. Geneva

    2002-01-01

    This International Standard establishes the safety identification colours and design principles for safety signs to be used in workplaces and in public areas for the purpose of accident prevention, fire protection, health hazard information and emergency evacuation. It also establishes the basic principles to be applied when developing standards containing safety signs. This part of ISO 3864 is applicable to workplaces and all locations and all sectors where safety-related questions may be posed. However, it is not applicable to the signalling used for guiding rail, road, river, maritime and air traffic and, generally speaking, to those sectors subject to a regulation which may differ.

  8. Probabilistic Methods for Uncertainty Propagation Applied to Aircraft Design

    Science.gov (United States)

    Green, Lawrence L.; Lin, Hong-Zong; Khalessi, Mohammad R.

    2002-01-01

    Three methods of probabilistic uncertainty propagation and quantification (the method of moments, Monte Carlo simulation, and a nongradient simulation search method) are applied to an aircraft analysis and conceptual design program to demonstrate design under uncertainty. The chosen example problems appear to have discontinuous design spaces and thus these examples pose difficulties for many popular methods of uncertainty propagation and quantification. However, specific implementation features of the first and third methods chosen for use in this study enable successful propagation of small uncertainties through the program. Input uncertainties in two configuration design variables are considered. Uncertainties in aircraft weight are computed. The effects of specifying required levels of constraint satisfaction with specified levels of input uncertainty are also demonstrated. The results show, as expected, that the designs under uncertainty are typically heavier and more conservative than those in which no input uncertainties exist.

  9. Applying riding-posture optimization on bicycle frame design.

    Science.gov (United States)

    Hsiao, Shih-Wen; Chen, Rong-Qi; Leng, Wan-Lee

    2015-11-01

    Customization design is a trend for developing a bicycle in recent years. Thus, the comfort of riding a bike is an important factor that should be paid much attention to while developing a bicycle. From the viewpoint of ergonomics, the concept of "fitting object to the human body" is designed into the bicycle frame in this study. Firstly, the important feature points of riding posture were automatically detected by the image processing method. In the measurement process, the best riding posture was identified experimentally, thus the positions of feature points and joint angles of human body were obtained. Afterwards, according to the measurement data, three key points: the handlebar, the saddle and the crank center, were identified and applied to the frame design of various bicycle types. Lastly, this study further proposed a frame size table for common bicycle types, which is helpful for the designer to design a bicycle. PMID:26154206

  10. Applying Adaptive Agricultural Management & Industrial Ecology Principles to Produce Lower- Carbon Ethanol from California Energy Beets

    Science.gov (United States)

    Alexiades, Anthy Maria

    The life cycle assessment of a proposed beet-to-ethanol pathway demonstrates how agricultural management and industrial ecology principles can be applied to reduce greenhouse gas emissions, minimize agrochemical inputs and waste, provide ecosystem services and yield a lower-carbon fuel from a highly land-use efficient, first-generation feedstock cultivated in California. Beets grown in California have unique potential as a biofuel feedstock. A mature agricultural product with well-developed supply chains, beet-sugar production in California has contracted over recent decades, leaving idle production capacity and forcing growers to seek other crops for use in rotation or find a new market for beets. California's Low Carbon Fuel Standard (LCFS) faces risk of steeply-rising compliance costs, as greenhouse gas reduction targets in the transportation sector were established assuming commercial volumes of lower-carbon fuels from second-generation feedstocks -- such as residues, waste, algae and cellulosic crops -- would be available by 2020. The expected shortfall of cellulosic ethanol has created an immediate need to develop lower-carbon fuels from readily available feedstocks using conventional conversion technologies. The life cycle carbon intensity of this ethanol pathway is less than 28 gCO2e/MJEthanol: a 72% reduction compared to gasoline and 19% lower than the most efficient corn ethanol pathway (34 gCO2e/MJ not including indirect land use change) approved under LCFS. The system relies primarily on waste-to-energy resources; nearly 18 gCO2e/MJ are avoided by using renewable heat and power generated from anaerobic digestion of fermentation stillage and gasification of orchard residues to meet 88% of the facility's steam demand. Co-products displace 2 gCO2e/MJ. Beet cultivation is the largest source of emissions, contributing 15 gCO 2e/MJ. The goal of the study is to explore opportunities to minimize carbon intensity of beet-ethanol and investigate the potential

  11. The Impact of People-Oriented Principle on Package Design

    Institute of Scientific and Technical Information of China (English)

    侯咏雪

    2014-01-01

    In modern design, it’s frequently advocated to adopt the recyclable and sustainable design as well as to use green and sustainable materials, which is a manifestation of the harmony between man and the nature.

  12. Teaching principles of qualitative analysis to industrial design engineers

    NARCIS (Netherlands)

    Stappers, P.J.

    2012-01-01

    Doing qualitative field research has become a standard part of academic human-centered design education. Part of the challenge is to bring design students a thorough understanding of research methods, and practical skills in performing small scale user research as part of design projects. This invo

  13. Magnetoelectic multiferroic superlattices and interfaces: Designing spintronic materials from first principles

    Science.gov (United States)

    Zanolli, Zeila

    2015-03-01

    The research challenges of the near and far future in electronics focus on the quest for new materials and novel device concepts to achieve low energy consumption, increased reliability and high device density. These can be obtained by designing active elements and interconnects whose operating principle is not (only) based on the electron charge but on the spin degree of freedom of the electron. The nanoscopic size of the materials calls for atomistic and parameter free (ab initio) simulations, which have proven to be crucial in achieving the necessary accuracy and predictive power. Materials which present a coupling between ferroelectricity and magnetism, i.e. magnetoelectric (ME) multiferroics, have been proposed as fundamental building blocks for spintronic devices. However ferroelectricity and magnetism are often exclusive or weakly coupled in bulk. In this talk, we will discuss how superlattices of perovskites can be designed from first principles to achieve strongly coupled ME and, hence, achieve control the weak magnetization via an electric field. Most important, advanced epitaxial techniques allow one to actually grow such magnetoelectric superlattices. Another route to optimize spintronic devices is to exploit the unique electronic and transport properties of Carbon-based nanomaterials. The latter present spin diffusion lengths up to 100 μm and high electron velocity. However, a large spin diffusion length comes at the price of small Spin Orbit coupling, which limits the possibility of manipulating electrons via an external applied field. Further, to achieve graphene-based devices one also needs to open its vanishing electronic gap. We use first principle techniques to show that placing graphene on a ME substrate can overcome these limitations by inducing magnetism and opening an electronic band-gap in the hybrid organic-multiferroic material. Z.Z. acknowledges EC support under the Marie-Curie IEF (PIEF-Ga-2011-300036), computational resources from the

  14. Applying the maximum information principle to cell transmission model of tra-ffic flow

    Institute of Scientific and Technical Information of China (English)

    刘喜敏; 卢守峰

    2013-01-01

    This paper integrates the maximum information principle with the Cell Transmission Model (CTM) to formulate the velo-city distribution evolution of vehicle traffic flow. The proposed discrete traffic kinetic model uses the cell transmission model to cal-culate the macroscopic variables of the vehicle transmission, and the maximum information principle to examine the velocity distri-bution in each cell. The velocity distribution based on maximum information principle is solved by the Lagrange multiplier method. The advantage of the proposed model is that it can simultaneously calculate the hydrodynamic variables and velocity distribution at the cell level. An example shows how the proposed model works. The proposed model is a hybrid traffic simulation model, which can be used to understand the self-organization phenomena in traffic flows and predict the traffic evolution.

  15. Using a problem-solving strategy to train students to apply general principles and to improve students' epistemology

    Science.gov (United States)

    McCoy, B.

    2011-12-01

    General studies science classes at many universities, such as physical science, Earth science, or astronomy, stress memorization and repetition of concepts. This approach leaves students with little appreciation for how science is used to explain phenomena from general principles. We present a novel instructional technique for an Earth science class in which the students are instructed in the use of a general problem solving strategy, adapted from a quantitative problem solving strategy developed by physics education research, in order to train the students in how to apply general principles. Using the Epistemological Beliefs Assessment for Physical Science, we have found that explicit training in problem solving significantly improves students' epistemology.

  16. Applied predictive analytics principles and techniques for the professional data analyst

    CERN Document Server

    Abbott, Dean

    2014-01-01

    Learn the art and science of predictive analytics - techniques that get results Predictive analytics is what translates big data into meaningful, usable business information. Written by a leading expert in the field, this guide examines the science of the underlying algorithms as well as the principles and best practices that govern the art of predictive analytics. It clearly explains the theory behind predictive analytics, teaches the methods, principles, and techniques for conducting predictive analytics projects, and offers tips and tricks that are essential for successful predictive mode

  17. Friction reduction using discrete surface textures: principle and design

    International Nuclear Information System (INIS)

    There have been many reports on the use of dimples, grooves, and other surface textures to control friction in sliding interfaces. The effectiveness of surface textures in friction reduction has been demonstrated in conformal contacts under high speed low load applications such as mechanical seals and automotive water pump seals, etc., resulting in reduced friction and longer durability. For sliding components with higher contact pressures or lower speeds, conflicting results were reported. Reasons for the inconsistency may be due to the differences in texture fabrication techniques, lack of dimple size and shape uniformity, and different tester used. This paper examines the basic principles on which surface textural patterns influence friction under the three principle lubrication regimes: hydrodynamic, elastohydrodynamic, and boundary lubrication regimes. Our findings suggest that each regime requires specific dimple size, shape, depth, and areal density to achieve friction reduction. Control experiments were also conducted to explore mechanisms of friction reduction. The dimple geometric shape and the dimple's orientation with respect to the sliding direction influence friction significantly. The underlying mechanisms for friction control via textures are discussed. (paper)

  18. Teaching the Principles of Effective Online Course Design: What Works?

    OpenAIRE

    Clare Gormley

    2014-01-01

    While much has been written about the pedagogy and challenges of online learning, there is comparatively little research that advises how online course design competencies can be achieved. Certainly a growing range of course design resources is being created and made openly available, but there is a need to evaluate their actual impact on practice. This predominantly qualitative study describes the impact of two learning interventions – open online tutorials and a design and development works...

  19. Design Challenges Today: An Overview of Its Sustainable Principles

    OpenAIRE

    Puyuelo Cazorla, Marina; Merino Sanjuan, Lola; Fernández Villalobos, Nieves

    2011-01-01

    Some approaches in the discipline¿s short history have marked the direction and type of commitments assumed by design and above all have offered a glimpse of where these challenges are pointing towards now. In fact, we find that design is not an independent activity but is always linked to a system which marks certain priorities according to the context. In order to reposition design objectives towards improving people's living conditions, modern society must deal with the serious...

  20. Experimental designs for autoregressive models applied to industrial maintenance

    International Nuclear Information System (INIS)

    Some time series applications require data which are either expensive or technically difficult to obtain. In such cases scheduling the points in time at which the information should be collected is of paramount importance in order to optimize the resources available. In this paper time series models are studied from a new perspective, consisting in the use of Optimal Experimental Design setup to obtain the best times to take measurements, with the principal aim of saving costs or discarding useless information. The model and the covariance function are expressed in an explicit form to apply the usual techniques of Optimal Experimental Design. Optimal designs for various approaches are computed and their efficiencies are compared. The methods working in an application of industrial maintenance of a critical piece of equipment at a petrochemical plant are shown. This simple model allows explicit calculations in order to show openly the procedure to find the correlation structure, needed for computing the optimal experimental design. In this sense the techniques used in this paper to compute optimal designs may be transferred to other situations following the ideas of the paper, but taking into account the increasing difficulty of the procedure for more complex models. - Highlights: • Optimal experimental design theory is applied to AR models to reduce costs. • The first observation has an important impact on any optimal design. • Either the lack of precision or small starting observations claim for large times. • Reasonable optimal times were obtained relaxing slightly the efficiency. • Optimal designs were computed in a predictive maintenance context

  1. A Learning and Interaction design framework, from a study on formulating principles for the design of engaging music learning games

    DEFF Research Database (Denmark)

    Weitze, Charlotte Lærke; Ørngreen, Rikke

    2012-01-01

    Based on a preliminary action research study investigating the design of digital music games and years of experiences from interaction design processes of learning resources, this extended abstract presents a framework that mixes designs for learning principles and game design with a process view...... using a simple interaction design lifecycle. Though the first outset was to design engaging music games, the resulting framework has a more generic character....

  2. Module Cluster: TTP-005.00 (GSC). Applied Behavior Analysis Principles.

    Science.gov (United States)

    Brent, George; And Others

    This module cluster enables (a) students to operationally define various classroom behaviors; (b) define and utilize behavioral principles; and (c) correctly employ measurement methods which facilitate information gathering, monitoring, and management of academic and/or "problem" classroom behaviors. It contains modules in the following ten areas:…

  3. Signaled Stopping and Cognitive, Language Principles Applied to Public Relations Writing.

    Science.gov (United States)

    Ramsey, Shirley A.

    To investigate the hypothesis that cognitive rules govern writing behavior, Carter's signaled stopping technique was used to study language and cognitive effects in public relations messages. Principles from Grunig, et al (1985) Axiomatic Theory of Cognition and Writing, which proposed premises, axioms and definitions about writing, were applied…

  4. Applying the Principle of Dynamic Equivalence in the Translation of the Heading of News Report

    Institute of Scientific and Technical Information of China (English)

    赵宁

    2008-01-01

    Nida's famous notion of Dynamic Equivalence in translation process is characterized by three stages - analysis,transfer and restructuring,which age explained in detail.The application of these principles are illustrated by providing step-by-step explanation on the translation process of headings of two news reports,which age selected from Far Eastern Economic Review.

  5. The immunoassay: Principles, development and potential applications in the applied plant sciences

    International Nuclear Information System (INIS)

    The article briefly discusses the general principles of, and the methods involved in, immunoassay, and their development. Emplasis is placed on radioimmunoassay (RIA) and to a lesser extent, enzyme-linked immunosorbent assay (ELISA). The practical applications, with special reference to the citrus and subtropical fruit industries are discussed

  6. Resisting Technological Gravity: Using Guiding Principles for Instructional Design

    Science.gov (United States)

    McDonald, Jason K.

    2010-01-01

    Instructional designers face tremendous pressure to abandon the essential characteristics of educational approaches, and settle instead for routine practices that do not preserve the level of quality those approaches originally expressed. Because this pressure can be strong enough to affect designers almost as gravity affects objects in the…

  7. Principles and Concepts for Information and Communication Technology Design.

    Science.gov (United States)

    Adams, Ray; Langdon, Patrick

    2003-01-01

    This article presents a theory for evaluating information and communication technology design for individuals with disabilities. Simplex 1 evaluates designs in five zones: sensory and input zone; output zone; abstract working memory; long-term memory; and central executive functioning. Simplex 2 evaluates feedback, emotional responses, cognitive…

  8. Inclusivity, Gestalt Principles, and Plain Language in Document Design

    Directory of Open Access Journals (Sweden)

    Jennifer Turner

    2016-06-01

    Full Text Available In Brief: Good design makes documents easier to use, helps documents stand out from other pieces of information, and lends credibility to document creators. Librarians across library types and departments provide instruction and training materials to co-workers and library users. For these materials to be readable and accessible, they must follow guidelines for usable document design. […

  9. Theory-generating practice. Proposing a principle for learning design

    DEFF Research Database (Denmark)

    Buhl, Mie

    2016-01-01

    building, and takes tacit knowledge into account. The article introduces TGP, contextualizes it to a Danish tradition of didactics, and discusses it in relation to contemporary conceptual currents of didactic design and learning design. This is followed by a theoretical framing of TGP. Finally, three...

  10. Adaptive Robotic Systems Design in University of Applied Sciences

    OpenAIRE

    Gunsing Jos; Gijselhart Fons; Hagemans Nyke; Jonkers Hans; Kivits Eric; Klijn Peter; Kapteijns Bart; Kroeske Diederich; Langen Hans; Oerlemans Bart; Oostindie Jan; van Stuijvenberg Joost

    2016-01-01

    In the industry for highly specialized machine building (small series with high variety and high complexity) and in healthcare a demand for adaptive robotics is rapidly coming up. Technically skilled people are not always available in sufficient numbers. A lot of know how with respect to the required technologies is available but successful adaptive robotic system designs are still rare. In our research at the university of applied sciences we incorporate new available technologies in our edu...

  11. Semantic Differential applied to the evaluation of machine tool design

    OpenAIRE

    Mondragón Donés, Salvador; Company, Pedro; Vergara Monedero, Margarita

    2005-01-01

    In this article, a study is presented showing that Product Semantics (PS) can be used to study the design of machine tools. Nowadays, different approaches to PS (Semantic Differential, Kansei Engineering, etc.) are being applied to consumer products with successful results, but commercial products have generally received less attention and machine tools in particular have not yet been studied. Our second objective is to measure the different sensitivities that the different groups of the popu...

  12. Some Ontological Principles for Designing Upper Level Lexical Resources

    CERN Document Server

    Guarino, N

    1998-01-01

    The purpose of this paper is to explore some semantic problems related to the use of linguistic ontologies in information systems, and to suggest some organizing principles aimed to solve such problems. The taxonomic structure of current ontologies is unfortunately quite complicated and hard to understand, especially for what concerns the upper levels. I will focus here on the problem of ISA overloading, which I believe is the main responsible of these difficulties. To this purpose, I will carefully analyze the ontological nature of the categories used in current upper-level structures, considering the necessity of splitting them according to more subtle distinctions or the opportunity of excluding them because of their limited organizational role.

  13. Constructal Law and the Unifying Principle of Design

    CERN Document Server

    Lorente, Sylvie; Bejan, Adrian

    2013-01-01

    Design happens everywhere, whether in animate objects (e.g., dendritic lung structures, bacterial colonies, and corals), inanimate patterns (river basins, beach slope, and dendritic crystals), social dynamics (pedestrian traffic flows), or engineered systems (heat dissipation in electronic circuitry). This “design in nature” often takes on remarkably similar patterns, which can be explained under one unifying Constructal Law. This book explores the unifying power of the Constructal Law and its applications in all domains of design generation and evolution, ranging from biology and geophysics to globalization, energy, sustainability, and security.  The Constructal Law accounts for the universal tendency of flow systems to morph into evolving configurations that provide greater and easier access over time. The Constructal Law resolves the many and contradictory ad hoc statements of “optimality”, end design, and destiny in nature, such as minimum and maximum entropy production and minimum and maximum fl...

  14. SOA and Web services interface design principles, techniques, and standards

    CERN Document Server

    Bean, James

    2009-01-01

    SOA offers solutions to the most intractable business problems faced by every enterprise, but getting the SOA service interface right requires the practical design knowledge this book uniquely delivers

  15. Kinematic couplings: A review of design principles and applications

    OpenAIRE

    Slocum, Alexander H.

    2009-01-01

    From the humble three-legged milking stool to a SEMI standard wafer pod location to numerous sub-micron fixturing applications in instruments and machines, exactly constrained mechanisms provide precision, robustness, and certainty of location and design. Kinematic couplings exactly constrain six degrees of freedom between two parts and hence closed-form equations can be written to describe the structural performance of the coupling. Hertz contact theory can also be used to design the contact...

  16. Ultra-thin oxide films for band engineering: design principles and numerical experiments

    International Nuclear Information System (INIS)

    The alignment of band energies between conductive oxides and semiconductors is crucial for the further development of oxide contacting layers in electronic devices. The growth of ultra thin films on the surface of an oxide material can be used to introduce a dipole moment at that surface due to charge differences. The dipole, in turn, alters the electrostatic potential — and hence the band energies — in the substrate oxide. We demonstrate the fundamental limits for the application of thin-films in this context, applying analytical and numerical simulations, that bridge continuum and atomistic. The simulations highlight the different parameters that can affect the band energy shifting potential of a given thin-film layer, taking the examples of MgO and SnO2. In particular we assess the effect of formal charge, layer orientation, layer thickness and surface coverage, with respect to their effect on the electrostatic potential. The results establish some design principles, important for further development and application of thin-films for band energy engineering in transparent conductive oxide materials. - Highlights: • Bridging continuum electrostatics and numerical point charge simulations. • Principles for engineering of band energies through application of ultra-thin films. • Effects of thin-film orientation on band energy levels • Effects of film-coverage and thickness on band energy levels

  17. Function and principle innovative design of mechanical products based on TRIZ/FA

    Institute of Scientific and Technical Information of China (English)

    YUAN Feng; WANG Tai-yong; NIE Hui-juan

    2006-01-01

    Function and principle innovation is the ultimate innovation of a product.To achieve Function and principle innovation design of mechanical products,a new process model of function and principle solving is proposed,based on TRIZ and FA.In this model,abstraction of general function,confirmation of principle solution to general function,and functional decomposition were included in FA.Confirmation of principle solution to general function was the premise of functional decomposition.To provide a dependable pattern for functional decomposition,a new functional analysis method was put forward based on the generalized process function along with the introduction of the input constraint function;and its five-decomposition-steps were also presented.To provide powerful support for innovation design tools in principle solution,some TRIZ tools in the model were imbedded,such as SU-field Analysis,Scientific Effects,and Contradiction Solving Principles so as to boost up the innovation of principle solution.As a case study,an innovative design of paint-bottling machine has been achieved with application of the proposed model.

  18. User Centered Design as a Framework for Applying Conversation Analysis in Hearing Aid Consultations

    DEFF Research Database (Denmark)

    Egbert, Maria; Matthews, Ben

    2011-01-01

    Recurrent issues in applying CA results to change in institutional practices concern the degree to which the CA researcher is involved and what aspects of the change process CA researchers is involved in. This paper presents a methodology from innovation studies called User Centered Design (Buur...... for innovation. Although this methodological convergence of disciplines is rooted in different traditions, it augurs well for successful cooperation. This paper reports on such a collaboration carried out within a federally funded research center for innovation. We present principles of the...

  19. In Search of Design Principles for Developing Digital Learning and Performance Support for a Student Design Task

    Science.gov (United States)

    Bollen, Lars; van der Meij, Hans; Leemkuil, Henny; McKenney, Susan

    2015-01-01

    A digital learning and performance support environment for university student design tasks was developed. This paper describes on the design rationale, process, and the usage results to arrive at a core set of design principles for the construction of such an environment. We present a collection of organizational, technical, and course-related…

  20. Relevant cost and financial ratio principles applied in a small business / G.P. Simpson.

    OpenAIRE

    Simpson, Gabriël Pieter

    2012-01-01

    Cost-Volume-Profit (CVP) analysis and financial ratios are all managerial accounting and financial accounting tools that can help managers to make informative business decisions within their organisations. In addition, certain strategic tools such as Porters five forces, SWOT analysis, identifying of core principles, the compilation of the vision and mission statement will empower the small to medium business to be successful as an entrepreneurial venture. The problem arises in many small ...

  1. Maximum Principle for Linear-Convex Boundary Control Problems applied to Optimal Investment with Vintage Capital

    OpenAIRE

    Faggian, Silvia

    2007-01-01

    The paper concerns the study of the Pontryagin Maximum Principle for an infinite dimensional and infinite horizon boundary control problem for linear partial differential equations. The optimal control model has already been studied both in finite and infinite horizon with Dynamic Programming methods in a series of papers by the same author, or by Faggian and Gozzi. Necessary and sufficient optimality conditions for open loop controls are established. Moreover the co-state variable is shown t...

  2. Applying Lean principles and Kaizen rapid improvement events in public health practice.

    Science.gov (United States)

    Smith, Gene; Poteat-Godwin, Annah; Harrison, Lisa Macon; Randolph, Greg D

    2012-01-01

    This case study describes a local home health and hospice agency's effort to implement Lean principles and Kaizen methodology as a rapid improvement approach to quality improvement. The agency created a cross-functional team, followed Lean Kaizen methodology, and made significant improvements in scheduling time for home health nurses that resulted in reduced operational costs, improved working conditions, and multiple organizational efficiencies. PMID:22139310

  3. Enterprise mashups: Design principles towards the long tail of user needs

    OpenAIRE

    Hoyer V.; Stanoesvka-Slabeva K.; Janner T.; Schroth C.

    2008-01-01

    A new type of Web-based applications, known as Enterprise Mashups, has been gaining momentum in the last years. Novel design principles are currently about to emerge allowing to cover the long tail of user needs and to provide individual and heterogeneous enterprise applications in a shorter time. In this paper, we introduce the main components of this new paradigm, and discuss the design principles of the architecture (Enterprise Mashup Stack), upcoming intermediaries and mass collaboration,...

  4. Exploring design principles for self service technologies: The case of a ticket vending machine

    OpenAIRE

    Seim, Marius

    2014-01-01

    The principal goal of this thesis was to research self service technologies used in public spaces, and how they can be improved upon. The main research question posed for this thesis was: "How well do the existing design principles support the ongoing development of self-service systems and are they su?cient?". There were also two sub-questions posed to further explore the topic: "How can novel design principles be used to improve the usability of self-service...

  5. Do Chickering and Gamson's Seven Principles Also Apply to Online MBAs?

    Directory of Open Access Journals (Sweden)

    J. B. (Ben Arbaugh

    2006-07-01

    Full Text Available Given a relative lack of empirical testing of conceptual frameworks of web-based course effectiveness, empirical testing of such frameworks is important because it can help determine similarities and/or differences in web-based and classroom-based courses. Such frameworks help determine whether and/or to what extent the training of faculty must be modified to prepare them adequately for online teaching. To assess whether conventional teaching wisdom needs to be modified for the online learning environment, we tested the applicability of a commonly-used framework, Chickering and Gamson’s (1987 Seven Principles of Good Practice in Education using a sample of twenty-four online MBA courses conducted at two Midwestern U. S. schools. The results support the extension of five from the seven principles of good practice in classroom-based undergraduate education to web-based graduate education. These findings suggest that principles of effective classroom teaching may be used as a starting point for developing and teaching web-based courses.

  6. Designing substrates for silicene and germanene: First-principles calculations

    Science.gov (United States)

    Chen, M. X.; Zhong, Z.; Weinert, M.

    2016-08-01

    We propose a guideline for exploring substrates that stabilize the monolayer honeycomb structure of silicene and germanene while simultaneously preserving the Dirac states: in addition to having a strong binding energy to the monolayer, a suitable substrate should be a large-gap semiconductor with a proper work function such that the Dirac point lies in the gap and far from the substrate states when their bands align. We illustrate our idea by performing first-principles calculations for silicene and germanene on the Al-terminated (0001) surface of Al2O3 . The overlaid monolayers on Al-terminated Al2O3 (0001) retain the main structural profile of the low-buckled honeycomb structure via a binding energy comparable to the one between silicene and Ag(111). An unfolded band structure derived from the k -projection method reveals that a gapped Dirac cone is formed at the K point due to the structural distortion and the interaction with the substrate. The gaps of 0.4 and 0.3 eV, respectively, for the supported silicene and germanene suggest that they may have potential applications in nanoelectronics.

  7. Issues in Applying Bio-Inspiration, Cognitive Critical Mass and Developmental-Inspired Principles to Advanced Intelligent Systems

    Science.gov (United States)

    Berg-Cross, Gary; Samsonovich, Alexei V.

    This Chapter summarizes ideas presented at the special PerMIS 2008 session on Biological Inspiration for Intelligent Systems. Bio-inspired principles of development and evolution are a special part of the bio-models and principles that can be used to improve intelligent systems and related artifacts. Such principles are not always explicit. They represent an alternative to incremental engineering expansion using new technology to replicate human intelligent capabilities. They are more evident in efforts to replicate and produce a “critical mass” of higher cognitive functions of the human mind or their emergence through cognitive developmental robotics (DR) and self-regulated learning (SRL). DR approaches takes inspiration from natural processes, so that intelligently engineered systems may create solutions to problems in ways similar to what we hypothesize is occurring with biologics in their natural environment. This Chapter discusses how an SRL-based approach to bootstrap a “critical mass” can be assessed by a set of cognitive tests. It also uses a three-level bio-inspired framework to illustrate methodological issues in DR research. The approach stresses the importance of using bio-realistic developmental principles to guide and constrain research. Of particular importance is keeping models and implementation separate to avoid the possible of falling into a Ptolemaic paradigm that may lead to endless tweaking of models. Several of Lungarella's design principles [36] for developmental robotics are discussed as constraints on intelligence as it emerges from an ecologically balanced, three-way interaction between an agents' control systems, physical embodiment, and the external environment. The direction proposed herein is to explore such principles to avoid slavish following of superficial bio-inspiration. Rather we should proceed with a mature and informed developmental approach using developmental principles based on our incremental understanding of how

  8. Computers as Components Principles of Embedded Computing System Design

    CERN Document Server

    Wolf, Wayne

    2008-01-01

    This book was the first to bring essential knowledge on embedded systems technology and techniques under a single cover. This second edition has been updated to the state-of-the-art by reworking and expanding performance analysis with more examples and exercises, and coverage of electronic systems now focuses on the latest applications. Researchers, students, and savvy professionals schooled in hardware or software design, will value Wayne Wolf's integrated engineering design approach.The second edition gives a more comprehensive view of multiprocessors including VLIW and superscalar archite

  9. The design principles of edutainment system for autistic children with communication difficulties

    Science.gov (United States)

    Hussain, Azham; Abdullah, Adil; Husni, Husniza

    2016-08-01

    Approximately 50% of all individuals with Autism have difficulties in developing functional language owing to communication deterioration. Mobile devices with installed educational games help these individuals feel more comfortable and relaxed doing such activities. Although numerous mobile applications are available for individuals with Autism, they are difficult to use; particularly in terms of user-interface design. From the analysis of existing apps for autistic children, an app design principles are proposed based on interaction design (IxD), that would fulfil the users' requirements in a better manner. Five applications were involved in this analysis. The analysis identified fifteen suggestions for the design principles. These recommendations are offered by this paper towards designing and developing a prototype app for autistic children. This paper introduces an edutainment-system design principle formulated to help develop the communication skills of children with Autism-spectrum disorders.

  10. Adaptive Robotic Systems Design in University of Applied Sciences

    Directory of Open Access Journals (Sweden)

    Gunsing Jos

    2016-01-01

    Full Text Available In the industry for highly specialized machine building (small series with high variety and high complexity and in healthcare a demand for adaptive robotics is rapidly coming up. Technically skilled people are not always available in sufficient numbers. A lot of know how with respect to the required technologies is available but successful adaptive robotic system designs are still rare. In our research at the university of applied sciences we incorporate new available technologies in our education courses by way of research projects; in these projects students will investigate the application possibilities of new technologies together with companies and teachers. Thus we are able to transfer knowledge to the students including an innovation oriented attitude and skills. Last years we developed several industrial binpicking applications for logistics and machining-factories with different types of 3D vision. Also force feedback gripping has been developed including slip sensing. Especially for healthcare robotics we developed a so-called twisted wire actuator, which is very compact in combination with an underactuated gripper, manufactured in one piece in polyurethane. We work both on modeling and testing the functions of these designs but we work also on complete demonstrator systems. Since the amount of disciplines involved in complex product and machine design increases rapidly we pay a lot of attention with respect to systems engineering methods. Apart from the classical engineering disciplines like mechanical, electrical, software and mechatronics engineering, especially for adaptive robotics more and more disciplines like industrial product design, communication … multimedia design and of course physics and even art are to be involved depending on the specific application to be designed. Design tools like V-model, agile/scrum and design-approaches to obtain the best set of requirements are being implemented in the engineering studies from

  11. Serious game design principles: The impact of game design on learning outcomes

    Science.gov (United States)

    Martin, Michael W.

    This dissertation examines the research question "How do video game design principles affect learning outcomes in serious games?" This research first develops a theoretical foundation concerning the meaning of the terms "game" and "serious game". This conceptual clarification is broken down into analytic propositions, which state that games have participants, rules, goals and challenges, and synthetic propositions, which state that the games should be intrinsically compelling, provide meaningful choices, and be self encapsulated. Based on these synthetic propositions, three hypotheses were developed. The hypotheses are that games with an enhanced aesthetic presentation, more meaningful choices, or provide player competition will elicit higher learning outcomes than identical games without these factors. These hypotheses were tested via a quantitative experiment involving 172 undergraduate students in the Old Dominion University Chemistry Department. The students were asked to play a chemistry-oriented serious game entitled Element Solitaire©, which was created by the research author. The students were randomly given different treatments of the Element Solitaire© game to play, and the difference between their learning outcomes were compared. The experimental results demonstrated that the aesthetic presentation of a game can have a significant impact upon the learning outcome. The experiment was not able to discern significant effects from the choice or competition conditions, but further examination of the experimental data did reveal some insight into these aspects of serious game design. Choices need to provide the player with options that have a sufficient value that they will be considered and the application of competition within games needs to be judiciously implemented to promote a positive affect for all players. The results of the theoretical foundations and empirical evidence were then combined with additional theoretical research to develop a set of

  12. Brownian molecular rotors: Theoretical design principles and predicted realizations

    OpenAIRE

    Schönborn, Jan Boyke; Herges, Rainer; Hartke, Bernd

    2009-01-01

    We propose simple design concepts for molecular rotors driven by Brownian motion and external photochemical switching. Unidirectionality and efficiency of the motion is measured by explicit simulations. Two different molecular scaffolds are shown to yield viable molecular rotors when decorated with suitable substituents.

  13. Three Principles for the Design of Energy Feedback Visualizations

    DEFF Research Database (Denmark)

    Brewer, Robert S.; Xu, Yongwen; Lee, George E.;

    2013-01-01

    To achieve the full benefits of the Smart Grid, end users must become active participants in the energy ecosystem. This paper presents the Kukui Cup challenge, a multifaceted serious game designed around the topic of energy conservation that incorporates a variety of energy feedback visualizations...

  14. Mammalian designer cells: Engineering principles and biomedical applications.

    Science.gov (United States)

    Xie, Mingqi; Fussenegger, Martin

    2015-07-01

    Biotechnology is a widely interdisciplinary field focusing on the use of living cells or organisms to solve established problems in medicine, food production and agriculture. Synthetic biology, the science of engineering complex biological systems that do not exist in nature, continues to provide the biotechnology industry with tools, technologies and intellectual property leading to improved cellular performance. One key aspect of synthetic biology is the engineering of deliberately reprogrammed designer cells whose behavior can be controlled over time and space. This review discusses the most commonly used techniques to engineer mammalian designer cells; while control elements acting on the transcriptional and translational levels of target gene expression determine the kinetic and dynamic profiles, coupling them to a variety of extracellular stimuli permits their remote control with user-defined trigger signals. Designer mammalian cells with novel or improved biological functions not only directly improve the production efficiency during biopharmaceutical manufacturing but also open the door for cell-based treatment strategies in molecular and translational medicine. In the future, the rational combination of multiple sets of designer cells could permit the construction and regulation of higher-order systems with increased complexity, thereby enabling the molecular reprogramming of tissues, organisms or even populations with highest precision. PMID:26010998

  15. Five Principles for MOOC Design: With a Case Study

    Science.gov (United States)

    Drake, John R.; O'Hara, Margaret; Seeman, Elaine

    2015-01-01

    New web technologies have enabled online education to take on a massive scale, prompting many universities to create massively open online courses (MOOCs) that take advantage of these technologies in a seemingly effortless manner. Designing a MOOC, however, is anything but trivial. It involves developing content, learning activities, and…

  16. Theory and principled methods for the design of metaheuristics

    CERN Document Server

    Borenstein, Yossi

    2013-01-01

    Metaheuristics, and evolutionary algorithms in particular, are known to provide efficient, adaptable solutions for many real-world problems, but the often informal way in which they are defined and applied has led to misconceptions, and even successful applications are sometimes the outcome of trial and error. Ideally, theoretical studies should explain when and why metaheuristics work, but the challenge is huge: mathematical analysis requires significant effort even for simple scenarios and real-life problems are usually quite complex.  In this book the editors establish a bridge between theo

  17. Oscillators as Systems and Synchrony as a Design Principle

    OpenAIRE

    Sepulchre, Rodolphe

    2005-01-01

    The chapter presents an expository survey of ongoing research by the author on a system theory for oscillators. Oscillators are regarded as open systems that can be interconnected to robustly stabilize ensemble phenomena characterized by a certain level of synchrony. The first part of the chapter provides examples of design (stabilization) problems in which synchrony plays an important role. The second part of the chapter shows that dissipativity theory provides an interconnect...

  18. Principle of Maximum Fisher Information from Hardy's Axioms Applied to Statistical Systems

    CERN Document Server

    Frieden, B R

    2014-01-01

    Consider a finite-sized, multidimensional system in parameter state a. The system is either at statistical equilibrium or general non-equilibrium, and may obey either classical or quantum physics. L. Hardy's mathematical axioms provide a basis for the physics obeyed by any such system. One axiom is that the number N of distinguishable states a in the system obeys N=max. This assumes that N is known as deterministic prior knowledge. However, most observed systems suffer statistical fluctuations, for which N is therefore only known approximately. Then what happens if the scope of the axiom N=max is extended to include such observed systems? It is found that the state a of the system must obey a principle of maximum Fisher information, I=I_{max}. This is important because many physical laws have been derived, assuming as a working hypothesis that I=I_{max}. These derivations include uses of the principle of Extreme physical information (EPI). Examples of such derivations were of the De Broglie wave hypothesis, q...

  19. POOLkits: Applying Object Oriented Principles from Software Engineering to Physics Object Oriented Learning -- Preliminary Concepts

    Science.gov (United States)

    Kassebaum, Thomas; Aubrecht, Gordon

    2012-04-01

    Object-oriented development depends upon the creation of generic pieces that can be built into more complex parts. In physics, we begin teaching basic principles and then develop more complex systems, a fertile environment to develop learning objects. Each learning object consists of observable quantities, such as the physical properties of a block of wood, and operators that act on the object, such as force. Additionally, each object can also include an assessment operator that evaluates the impact of the learning object on student comprehension. The physics object-oriented learning kits (POOLkits) will be developed to enhance student understanding of physics concepts, as well as, build a framework for developing a software object based on the physics concept. A POOLkit can be extended, similar to the concept of extending classes in object-oriented programming, as physics knowledge expands. The expectation for these POOLkits would be to provide physics students with a solid foundation in the first principles to be able to derive more complex formulae and have the understanding of the process with a secondary benefit of enhancing the object-oriented programming capabilities of physics students.

  20. Application of Systems Engineering Principles for Concept Design of New Products

    Science.gov (United States)

    Kumar, Karunakaran Nair Ajith; Jagathy Raj, Vettuvila Purushothaman

    2016-06-01

    A successful engineering design is one that meets the user requirements completely. Design essentially starts with concept design followed by detailed design. The importance of concept design is brought out in this paper. Systems engineering principles and practices are used to build the concept design starting from user requirements and user specified reference scenarios. Systems engineering methodology helps in proper understanding of the user requirements, identifying multiple solutions, short listing the candidate solutions and finally selecting one or two feasible designs. A case study analysis is presented to demonstrate the systems engineering practices followed for concept abstraction and preliminary design of a typical engineering system.

  1. Virtual Screening and Structure Generation Applied to Drug Design

    Institute of Scientific and Technical Information of China (English)

    FAN B.T.; CHEN H. F.; XIE L.; YUAN S. G.; A. PANAYE; J-P. DOUCET

    2004-01-01

    The methods of computer-aided drug design can be divided into two categories according to whether or not the structures of receptors are known1, corresponding to two principal strategies:(1) searching the bio-active ligands against virtual combinatorial libraries and calculating the affinity energy between ligand and receptor by docking ; (2) QSAR and 3D-structure data-mining.3D-QSAR method is now applied widely to drug discovery, but this method is generally limited to refine the structures of known bio-active compounds. During the process of drug design, we have usually the prejudice that certain groups or structural fragments will play or not important roles on the activity. This will sometimes be misleading, and prevent us from obtaining expected results.The method of generating firstly diverse structures, then screening out the promising structures by means of a computational method or QSAR model, is an efficient way for drug discovery. We developed an efficient virtual and rational drag design method. It combines virtual bioactive compound generation using genetic algorithms with 3D-QSAR model and docking. Using this method can generate a lot of highly diverse molecules and find virtual active lead compounds. The method was validated by the study on a set of anti-tumor drugs, colchicine analogs2. With the constraints of pharmacophore obtained determined by DISCO, 97 virtual bioactive compounds were generated,and their anti-tumor activities were predicted by CoMFA. 8 structures with high activity were selected and screened by 3D-QSAR model. The most active generated structure was further investigated by modifying its structure in order to increase the activity (see fig.1). This drug design method could also avoid the conflict between the insufficiency of active structures and the great quantity of compounds needed for high-throughput screening. This method has been also applied to anti-HIV drug design.We have developed equally another approach of virtual

  2. Design Principles for Achieving Integrated Healthcare Information Systems

    DEFF Research Database (Denmark)

    Jensen, Tina Blegind

    2013-01-01

    Achieving integrated healthcare information systems has become a common goal for many countries in their pursuit of obtaining coordinated and comprehensive healthcare services. This article focuses on how a small local project termed ‘Standardized pull of patient data’ expanded and is now used on a...... large scale providing a majority of hospitals, general practitioners and citizens across Denmark with the possibility of accessing healthcare data from different electronic patient record systems and other systems. I build on design theory for information infrastructures, as presented by Hanseth and...

  3. Design and Characterization of Photoelectrodes from First Principles

    Energy Technology Data Exchange (ETDEWEB)

    Ogitsu, T; Wood, B; Choi, W; Huda, M; Wei, S

    2012-05-11

    Although significant performance improvements have been realized since the first demonstration of sunlight-driven water splitting in 1972, mainstream adoption of photoelectrochemical (PEC) cells remains limited by an absence of cost-effective electrodes that show simultaneously high conversion efficiency and good durability. Here we outline current and future efforts to use advanced theoretical techniques to guide the development of a durable, high-performance PEC electrode material. Working in close collaboration with experimental synthesis and characterization teams, we use a twofold approach focusing on: (1) rational design of novel high-performance electrode materials; and (2) characterization and optimization of the electrode-electrolyte interface.

  4. Real-time embedded systems design principles and engineering practices

    CERN Document Server

    Fan, Xiaocong

    2015-01-01

    This book integrates new ideas and topics from real time systems, embedded systems, and software engineering to give a complete picture of the whole process of developing software for real-time embedded applications. You will not only gain a thorough understanding of concepts related to microprocessors, interrupts, and system boot process, appreciating the importance of real-time modeling and scheduling, but you will also learn software engineering practices such as model documentation, model analysis, design patterns, and standard conformance. This book is split into four parts to help you

  5. Designing Embedded Systems with PIC Microcontrollers Principles and Applications

    CERN Document Server

    Wilmshurst, Tim

    2009-01-01

    PIC microcontrollers are used worldwide in commercial and industrial devices. The 8-bit PIC which this book focuses on is a versatile work horse that completes many designs. An engineer working with applications that include a microcontroller will no doubt come across the PIC sooner rather than later. It is a must to have a working knowledge of this 8-bit technology. This book takes the novice from introduction of embedded systems through to advanced development techniques for utilizing and optimizing the PIC family of microcontrollers in your device. To truly understand the PIC, assembly and

  6. Genetic algorithms applied to nuclear reactor design optimization

    International Nuclear Information System (INIS)

    A genetic algorithm is a powerful search technique that simulates natural evolution in order to fit a population of computational structures to the solution of an optimization problem. This technique presents several advantages over classical ones such as linear programming based techniques, often used in nuclear engineering optimization problems. However, genetic algorithms demand some extra computational cost. Nowadays, due to the fast computers available, the use of genetic algorithms has increased and its practical application has become a reality. In nuclear engineering there are many difficult optimization problems related to nuclear reactor design. Genetic algorithm is a suitable technique to face such kind of problems. This chapter presents applications of genetic algorithms for nuclear reactor core design optimization. A genetic algorithm has been designed to optimize the nuclear reactor cell parameters, such as array pitch, isotopic enrichment, dimensions and cells materials. Some advantages of this genetic algorithm implementation over a classical method based on linear programming are revealed through the application of both techniques to a simple optimization problem. In order to emphasize the suitability of genetic algorithms for design optimization, the technique was successfully applied to a more complex problem, where the classical method is not suitable. Results and comments about the applications are also presented. (orig.)

  7. Building with Nature (Ecological Principles in Building Design

    Directory of Open Access Journals (Sweden)

    Akubue Jideofor Anselm

    2006-01-01

    Full Text Available The main objective here is to confer ideas aimed at creating environmentally friendly, energy efficient buildings, developed by effectively managing natural resources. This entails passively and actively harnessing solar energy and using materials which, in their manufacture, application and disposal, do the least possible damage to nature`s `free resources`; water, ground and air. This study provides ideas on the effective management of nature in building design and the process of integration with nature. Such ideas as ecological replacement scheme or ecology integration using traditional concepts of natural landform integration, natural orientation and effective methods of harnessing the climatic resources like the sun and winds and a breakdown on the modes of building material selection and application to suit geographical and climatic conditions are among the issues discussed in this study. The major emphasis here is to utilize these natural resources integrated effectively in design and building in order to achieve sustainability, energy efficiency and most importantly an ecological and healthy living environment devoid of waste and with minimized environmental pollution.

  8. Design principles of the yeast G1/S switch.

    Directory of Open Access Journals (Sweden)

    Xiaojing Yang

    2013-10-01

    Full Text Available A hallmark of the G1/S transition in budding yeast cell cycle is the proteolytic degradation of the B-type cyclin-Cdk stoichiometric inhibitor Sic1. Deleting SIC1 or altering Sic1 degradation dynamics increases genomic instability. Certain key facts about the parts of the G1/S circuitry are established: phosphorylation of Sic1 on multiple sites is necessary for its destruction, and both the upstream kinase Cln1/2-Cdk1 and the downstream kinase Clb5/6-Cdk1 can phosphorylate Sic1 in vitro with varied specificity, cooperativity, and processivity. However, how the system works as a whole is still controversial due to discrepancies between in vitro, in vivo, and theoretical studies. Here, by monitoring Sic1 destruction in real time in individual cells under various perturbations to the system, we provide a clear picture of how the circuitry functions as a switch in vivo. We show that Cln1/2-Cdk1 sets the proper timing of Sic1 destruction, but does not contribute to its destruction speed; thus, it acts only as a trigger. Sic1's inhibition target Clb5/6-Cdk1 controls the speed of Sic1 destruction through a double-negative feedback loop, ensuring a robust all-or-none transition for Clb5/6-Cdk1 activity. Furthermore, we demonstrate that the degradation of a single-phosphosite mutant of Sic1 is rapid and switch-like, just as the wild-type form. Our mathematical model confirms our understanding of the circuit and demonstrates that the substrate sharing between the two kinases is not a redundancy but a part of the design to overcome the trade-off between the timing and sharpness of Sic1 degradation. Our study provides direct mechanistic insight into the design features underlying the yeast G1/S switch.

  9. On the importance of agile communication skills in BPM education: Design principles for international seminars

    Directory of Open Access Journals (Sweden)

    Jan vom Brocke

    2012-12-01

    Full Text Available Business Process Management (BPM has evolved as an integrated management discipline that aims to enable organizations to continuously innovate and improve their operations. BPM experts are exposed to communication processes involving people from various backgrounds (e.g., various business areas, fields of expertise, and cultures. Research in applied linguistics has shown that it is difficult to plan for constellations of such communication processes; thus, agile communication skills are vital for successful business communication. Teaching programs for BPM, however, do not account for these skills. Rather, they mainly address methods for the analysis, implementation, and management of business processes. As a result, graduates—though they may be technically and methodologically apt—face unexpected challenges due to communication deficiencies in BPM projects. BPM research has shown that deficiencies in communication are in fact among the most frequent reasons for project failure. In this paper, we present a course setting to teach agile communication skills in BPM education. The approach is informed by literature on BPM education as well as theories from virtual collaboration education. We have evaluated it in an international virtual seminar involving seven European universities. We argue for the importance of agile communication skills in BPM education. In addition, we present design principles for courses to teach agile communication skills that can be applied by fellow academics.

  10. Future Research in Agile Systems Development: Applying Open Innovation Principles Within the Agile Organisation

    Science.gov (United States)

    Conboy, Kieran; Morgan, Lorraine

    A particular strength of agile approaches is that they move away from ‘introverted' development and intimately involve the customer in all areas of development, supposedly leading to the development of a more innovative and hence more valuable information system. However, we argue that a single customer representative is too narrow a focus to adopt and that involvement of stakeholders beyond the software development itself is still often quite weak and in some cases non-existent. In response, we argue that current thinking regarding innovation in agile development needs to be extended to include multiple stakeholders outside the business unit. This paper explores the intra-organisational applicability and implications of open innovation in agile systems development. Additionally, it argues for a different perspective of project management that includes collaboration and knowledge-sharing with other business units, customers, partners, and other relevant stakeholders pertinent to the business success of an organisation, thus embracing open innovation principles.

  11. Strengthening the effectiveness of patient education: applying principles of adult education.

    Science.gov (United States)

    Padberg, R M; Padberg, L F

    1990-01-01

    In spite of the recognized significance of patient education, many factors contribute to difficulties in providing effective patient teaching: diminished time from reduced hospital stays, the shortage of nursing personnel, and often, the patient's compromised physical and emotional status. With these constraints, teaching must be effective and efficient. In reviewing the literature, primary emphasis was found on providing sound clinical information with little attention to the techniques of effective methods for teaching adults. This article draws upon the principles of andragogy--the methods of teaching adults delineated by Malcolm Knowles--to provide a conceptual framework for developing effective patient education practice. Examples of both effective and ineffective practice are provided from the nursing literature. The information provided should assist nurses in understanding how adults learn and provide them with a structure to use in tailoring their teaching to meet the individual needs of their patients. PMID:2300506

  12. Software engineering principles applied to large healthcare information systems--a case report.

    Science.gov (United States)

    Nardon, Fabiane Bizinella; de A Moura, Lincoln

    2007-01-01

    São Paulo is the largest city in Brazil and one of the largest cities in the world. In 2004, São Paulo City Department of Health decided to implement a Healthcare Information System to support managing healthcare services and provide an ambulatory health record. The resulting information system is one of the largest public healthcare information systems ever built, with more than 2 million lines of code. Although statistics shows that most software projects fail, and the risks for the São Paulo initiative were enormous, the information system was completed on-time and on-budget. In this paper, we discuss the software engineering principles adopted that allowed to accomplish that project's goals, hoping that sharing the experience of this project will help other healthcare information systems initiatives to succeed. PMID:17911673

  13. Making Blended Instruction Better: Integrating the Principles of Universal Design for Instruction into Course Design and Delivery

    Science.gov (United States)

    Dukes, Lyman L., III; Koorland, Mark A.; Scott, Sally S.

    2009-01-01

    Online instruction in general and blended instruction in particular have gained a sizable and permanent foothold in postsecondary educational environments. In addition, student diversity has become the norm. Universal design for instruction is a framework that consists of nine principles for instructional design and delivery; it proposes that…

  14. 49 CFR 236.5 - Design of control circuits on closed circuit principle.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Design of control circuits on closed circuit..., AND APPLIANCES Rules and Instructions: All Systems General § 236.5 Design of control circuits on closed circuit principle. All control circuits the functioning of which affects safety of train...

  15. Researching Principles of Lesson Design to Realize the Pedagogical Opportunities of Mathematics Analysis Software

    Science.gov (United States)

    Pierce, Robyn; Stacey, Kaye

    2009-01-01

    Taking advantage of pedagogical opportunities afforded by new technology requires appropriately designed lessons. This article reports on the use of "lesson study" to research principles for the design of a lesson aiming to take advantage of multiple representations. The lesson, for year 10 students who had personal access to TI-Nspire, focused on…

  16. Sociosexuality Education for Persons with Autism Spectrum Disorders Using Principles of Applied Behavior Analysis

    Science.gov (United States)

    Wolfe, Pamela S.; Condo, Bethany; Hardaway, Emily

    2009-01-01

    Applied behavior analysis (ABA) has emerged as one of the most effective empirically based strategies for instructing individuals with autism spectrum disorders (ASD). Four ABA-based strategies that have been found effective are video modeling, visual strategies, social script fading, and task analysis. Individuals with ASD often struggle with…

  17. Students as Employees: Applying Performance Management Principles in the Management Classroom

    Science.gov (United States)

    Gillespie, Treena L.; Parry, Richard O.

    2009-01-01

    The student-as-employee metaphor emphasizes student accountability and participation in learning and provides instructors with work-oriented methods for creating a productive class environment. The authors propose that the tenets of performance management in work organizations can be applied to the classroom. In particular, they focus on three…

  18. A Self-Administered Parent Training Program Based upon the Principles of Applied Behavior Analysis

    Science.gov (United States)

    Maguire, Heather M.

    2012-01-01

    Parents often respond to challenging behavior exhibited by their children in such a way that unintentionally strengthens it. Applied behavior analysis (ABA) is a research-based science that has been proven effective in remediating challenging behavior in children. Although many parents could benefit from using strategies from the field of ABA with…

  19. Designing Crop Simulation Web Service with Service Oriented Architecture Principle

    Science.gov (United States)

    Chinnachodteeranun, R.; Hung, N. D.; Honda, K.

    2015-12-01

    Crop simulation models are efficient tools for simulating crop growth processes and yield. Running crop models requires data from various sources as well as time-consuming data processing, such as data quality checking and data formatting, before those data can be inputted to the model. It makes the use of crop modeling limited only to crop modelers. We aim to make running crop models convenient for various users so that the utilization of crop models will be expanded, which will directly improve agricultural applications. As the first step, we had developed a prototype that runs DSSAT on Web called as Tomorrow's Rice (v. 1). It predicts rice yields based on a planting date, rice's variety and soil characteristics using DSSAT crop model. A user only needs to select a planting location on the Web GUI then the system queried historical weather data from available sources and expected yield is returned. Currently, we are working on weather data connection via Sensor Observation Service (SOS) interface defined by Open Geospatial Consortium (OGC). Weather data can be automatically connected to a weather generator for generating weather scenarios for running the crop model. In order to expand these services further, we are designing a web service framework consisting of layers of web services to support compositions and executions for running crop simulations. This framework allows a third party application to call and cascade each service as it needs for data preparation and running DSSAT model using a dynamic web service mechanism. The framework has a module to manage data format conversion, which means users do not need to spend their time curating the data inputs. Dynamic linking of data sources and services are implemented using the Service Component Architecture (SCA). This agriculture web service platform demonstrates interoperability of weather data using SOS interface, convenient connections between weather data sources and weather generator, and connecting

  20. Principles of Designing and Implementing Agricultural Extension Programs for Reducing Post-harvest Loss

    OpenAIRE

    Paul E. McNamara; Joyous S. Tata

    2015-01-01

    Post-harvest losses represent a significant threat to food security and farmer incomes worldwide. It is an inefficiency in the global food production system that is avoidable. In deducing principles of designing and implementing agricultural extension programs to reduce post-harvest losses, valuable lessons can be gleaned from the handful of previous extension projects and programs addressing post-harvest loss. Abstracting principles from previous experiences and using this to inform future p...

  1. Making Design Decisions Visible: Applying the Case-Based Method in Designing Online Instruction

    Directory of Open Access Journals (Sweden)

    Heng Luo,

    2011-01-01

    Full Text Available The instructional intervention in this design case is a self-directed online tutorial that applies the case-based method to teach educators how to design and conduct entrepreneurship programs for elementary school students. In this article, the authors describe the major decisions made in each phase of the design and development process, explicate the rationales behind them, and demonstrate their effect on the production of the tutorial. Based on such analysis, the guidelines for designing case-based online instruction are summarized for the design case.

  2. Optimisation of a pillow production line applying Lean principles 

    OpenAIRE

    Fookes, William

    2010-01-01

    Manufacturing companies throughout the world are interested in reducing the time between a customer placing an order and them receiving the payment for that order. This premise is something that is a central characteristic for the Lean philosophy, and is one of the reasons to apply it. Today manufacturers around the world are embracing Lean techniques in order to reduce waste and increase productivity, and also increase the inventory turns, which reflects in an improvement of cash flow for th...

  3. Review: Janice M. Morse & Linda Niehaus (2009). Mixed Method Design: Principles and Procedures

    OpenAIRE

    Öhlen, Joakim

    2010-01-01

    Mixed method design related to the use of a combination of methods, usually quantitative and qualitative, is increasingly used for the investigation of complex phenomena. This review discusses the book, "Mixed Method Design: Principles and Procedures," by Janice M. MORSE and Linda NIEHAUS. A distinctive feature of their approach is the consideration of mixed methods design out of a core and a supplemental component. In order to define these components they emphasize the overall conceptual dir...

  4. Review: Janice M. Morse & Linda Niehaus (2009). Mixed method design: principles and procedures

    OpenAIRE

    Öhlen, Joakim

    2010-01-01

    Mixed-Method-Designs, in denen quantitative und qualitative Methoden Verwendung finden, erfreuen sich zunehmender Beliebtheit für die Untersuchung komplexer Phänomene. Die vorliegende Besprechung beschäftigt sich in diesem Zusammenhang mit dem Buch "Mixed Method Design: Principles and Procedures" von Janice M. MORSE und Linda NIEHAUS, die für solche Designs Kern- und Ergänzungskomponenten zu identifizieren versuchen. Hierzu differenzieren sie zwischen Projekten, die einer eher deduktiven oder...

  5. Recycling industrial architecture : the redefinition of the recycling principles in the context of sustainable architectural design

    OpenAIRE

    Šijaković, Milan

    2015-01-01

    The aim of this thesis is the elucidation of the concept of architectural recycling as an environmentally sustainable alternative to demolition and preservation. More precisely, the research aim relates to the redefinition of recycling design principles in the context of the sustainable architectural design. The process of architectural recycling was placed in the context of a sustainable architectural design, as the global concept of sustainable development is imposed as a general context fo...

  6. Pacific Canada's Rockfish Conservation Areas: using Ostrom's design principles to assess management effectiveness

    Directory of Open Access Journals (Sweden)

    Darienne Lancaster

    2015-09-01

    Full Text Available International declines in marine biodiversity have lead to the creation of marine protected areas and fishery reserve systems. In Canada, 164 Rockfish Conservation Areas (RCAs were implemented between 2003 and 2007 and now cover 4847.2 km² of ocean. These reserves were created in response to widespread concern from fishers and nongovernmental organizations about inshore rockfish (genus Sebastes population declines. We used the design principles for effective common-pool resource management systems, originally developed by Elinor Ostrom, to assess the social and ecological effectiveness of these conservation areas more than 10 years after their initial implementation. We assessed the relative presence or absence of each design principle within current RCA management. We found that 2 of the 11 design principles were moderately present in the recreational fishery. All other design principles were lacking for the recreational sector. We found that 2 design principles were fully present and 5 were moderately present in the commercial sector. Four design principles were lacking in the commercial sector. Based on this analysis, we highlight 4 main areas for management improvement: (1 create an education and outreach campaign to explain RCA rules, regulations, boundaries, and the need for marine conservation; (2 increase monitoring of users and resources to discourage noncompliance and gather the necessary data to create social buy-in for marine conservation; (3 encourage informal nested governance through stakeholder organizations for education and self-regulation (e.g. fisher to fisher; and (4 most importantly, create a formal, decadal RCA review process to gather stakeholder input and make amendments to regulations and RCA boundaries. This information can be used to inform spatial management systems both in Canada and internationally. This analysis also contributes to a growing literature on effectively scaling up small-scale management techniques

  7. The roles and uses of design principles for developing the trialogical approach on learning

    Directory of Open Access Journals (Sweden)

    Kari Kosonen

    2011-12-01

    Full Text Available In the present paper, the development and use of a specific set of pedagogical design principles in a large research and development project are analysed. The project (the Knowledge Practices Laboratory developed technology and a pedagogical approach to support certain kinds of collaborative knowledge creation practices related to the ‘trialogical' approach on learning. The design principles for trialogical learning are examined from three main developmental perspectives that were emphasised in the project: theory, pedagogy, and technology. As expected, the design principles had many different roles but not as straightforward or overarching as was planned. In their outer form they were more resistant to big changes than was expected but they were elaborated and specified during the process. How theories change in design-based research is discussed on the basis of the analysis. Design principles are usually seen as providing a bridge between theory and practice, but the present case showed that also complementary, more concrete frameworks are needed for bridging theory to practical pedagogical or technical design solutions.

  8. Null testing of nonrotational symmetry transmission optical freeform: design, modeling, and inspection on the basis of Fermat principles

    Science.gov (United States)

    Qiu, Gufeng; Cui, Xudong

    2015-11-01

    We present a general design method for a type of transmission freeforms without rotational symmetry and achieve the null testing by putting a well-designed Fermat reflector on the transmitting optical path. The design principle of the reflector is given, and an eccentric spherical surface with 1-mm deviation is used as an example of testing freeform. We fabricated the reflector and the freeform with the single-point diamond turning machine. Both conventional interference inspection and our approach give consistent results. The design error is less than 106 mm, and the measurement accuracy is nearly completely determined by the fabrication precision. This approach can also be applied to the inspections of reflecting freeforms with low costs.

  9. E-learning Materials Development: Applying and Implementing Software Reuse Principles and Granularity Levels in the Small

    Directory of Open Access Journals (Sweden)

    Nabil Arman

    2010-06-01

    Full Text Available E-learning materials development is typically acknowledged as an expensive, complicated, and lengthy process, often producing materials that are of low quality and difficult to adaptand maintain. It has always been a challenge to identify proper e-learning materials that can be reused at a reasonable cost and effort. In this paper, software engineering reuse principlesare applied to e-learning materials development process. These principles are then applied and implemented in a prototype that is integrated with an open-source course management systems. The reuse of existing e-learning materials is beneficial in improving developers of elearning materials productivity. E-learning material reuse is performed, in this research, based on construct’s granularity rather than on unified constructs of one size.

  10. Raising Children in an Evangelical Family Environment: Biblical Principles Applied to the Family

    OpenAIRE

    Ljubinka Jambrek

    2009-01-01

    As Creator, God designed the family and determined the standards and rules for living and functioning in the family. As a basic unit of society, the family is to reflect God’s glory. God’s plan for marriage and the family has not changed, only the human approach to this institution has changed. Therefore, it is vital to re-emphasize how important it is that the family functions according to biblical standards. This article deals with raising children in an evangelical environment which assume...

  11. Physical chemistry research for engineering and applied sciences, v.1 principles and technological implications

    CERN Document Server

    Pearce, Eli M; Pethrick, Richard A

    2015-01-01

    PrefaceBacterial Poly(3-Hydroxybutyrate) as a Biodegradable Polymer for Biomedicine; A. L. Iordanskii, G. A. Bonartseva, T. A. Makhina, E. D. Sklyanchuk, and G. E. ZaikovThe Effect of Antioxidant Drug Mexidol on Bioenergetic Processes and Nitric Oxide Formation in the Animal Tissues; Z. V. Kuropteva, O. L. Belaya, L. M. Baider, and T. N. BogatyrenkoCalcium Soap Lubricants; Alazizer, Tugce Nefise Kahyaoglu, and Devrim BalköseRadical Scavenging Capacity of N-(2-Mercapto-2-Methylpropionyl)-L-Cysteine: Design and Synthesis of Its Derivative with

  12. Raising Children in an Evangelical Family Environment: Biblical Principles Applied to the Family

    Directory of Open Access Journals (Sweden)

    Ljubinka Jambrek

    2009-10-01

    Full Text Available As Creator, God designed the family and determined the standards and rules for living and functioning in the family. As a basic unit of society, the family is to reflect God’s glory. God’s plan for marriage and the family has not changed, only the human approach to this institution has changed. Therefore, it is vital to re-emphasize how important it is that the family functions according to biblical standards. This article deals with raising children in an evangelical environment which assumes God’s presence, the reading and keeping of God’s Word, love between the parents, prayer, and worship of God. Clear goals for raising children are presented. This work offers valuable and lived examples of biblical discipline. It discusses the topic of discipline from childhood to the teen ages, trust, responsibility, communication and relationship with God. Finally, the article points out the importance of times of family worship.

  13. Principles underlying the design of "The Number Race", an adaptive computer game for remediation of dyscalculia

    Directory of Open Access Journals (Sweden)

    Cohen Laurent

    2006-05-01

    Full Text Available Abstract Background Adaptive game software has been successful in remediation of dyslexia. Here we describe the cognitive and algorithmic principles underlying the development of similar software for dyscalculia. Our software is based on current understanding of the cerebral representation of number and the hypotheses that dyscalculia is due to a "core deficit" in number sense or in the link between number sense and symbolic number representations. Methods "The Number Race" software trains children on an entertaining numerical comparison task, by presenting problems adapted to the performance level of the individual child. We report full mathematical specifications of the algorithm used, which relies on an internal model of the child's knowledge in a multidimensional "learning space" consisting of three difficulty dimensions: numerical distance, response deadline, and conceptual complexity (from non-symbolic numerosity processing to increasingly complex symbolic operations. Results The performance of the software was evaluated both by mathematical simulations and by five weeks of use by nine children with mathematical learning difficulties. The results indicate that the software adapts well to varying levels of initial knowledge and learning speeds. Feedback from children, parents and teachers was positive. A companion article 1 describes the evolution of number sense and arithmetic scores before and after training. Conclusion The software, open-source and freely available online, is designed for learning disabled children aged 5–8, and may also be useful for general instruction of normal preschool children. The learning algorithm reported is highly general, and may be applied in other domains.

  14. The Principles of Conservation and Development: Do They Apply in Malinau?

    Directory of Open Access Journals (Sweden)

    Patrice Levang

    2007-12-01

    Full Text Available Attempts to reconcile economic development with environmental conservation in a forest area in East Kalimantan, Indonesia, are reviewed for the district of Malinau, East Kalimantan, Indonesia, an area of 42,000 km2 that is still largely covered in rainforest. The history of the region is described and the conservation and development impacts of external drivers of change are assessed. Both government and conservation organizations have subscribed to the rhetoric of pursuing development pathways that would be sustainable and would conserve the rich biodiversity of the area. Three distinct approaches to conservation have been attempted. First spatial planning has been used to attribute land to different uses and particularly to identify and designate protected areas. Second, measures have been taken to lessen the negative environmental impact of industrial logging and to promote the preservation of biodiversity in logged forests. Last, decentralized and community-based management has been promoted on the assumption that this would yield better environmental and social outcomes than large-scale industrial development. These conservation measures have been pursued during a period when the governance of the region has been weak. Corruption, political collusion, and nepotism have been major factors in decision making about natural resources. We argue that a sustainable future for the district of Malinau must lie in finding an appropriate balance between protected areas, forests managed at both industrial and community scales, and land conversion. However, there is little empirical evidence that allows the outcomes of these approaches to be measured. The problem of knowing how conservation investments can be made in ways that optimize sustainable benefits to local livelihoods remains largely unresolved. A number of possible conservation and development pathways for the district are discussed.

  15. 10 CFR 435.6 - Sustainable principles for siting, design and construction. [Reserved

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Sustainable principles for siting, design and construction. 435.6 Section 435.6 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY STANDARDS FOR NEW FEDERAL LOW-RISE RESIDENTIAL BUILDINGS Mandatory Energy Efficiency Standards for Federal Low-Rise Residential Buildings. § 435.6...

  16. PBMR phase 1 study: Seismic and structural design consideration - An overview of principles

    International Nuclear Information System (INIS)

    This paper briefly reviews the principles involved in the planning and design of the proposed facility to cater for seismic and structural loads. The conceptual layout is discussed, as well as the different load characteristics and scenarios. An outline is given of model used to estimate the seismic loads, whereafter the different analytical models are discussed. (author)

  17. To Design and Evaluate a 12th Grade Course in the Principles of Economics; Final Report.

    Science.gov (United States)

    Wiggins, Suzanne E.; Sperling, John G.

    Reported is the design, development, and evaluation of a one-semester course on the principles of economics for twelfth grade students. The course is intended to develop students' capacity for economic reasoning through economic theory and empirical research. To do this, teaching materials and innovative techniques for teacher training were…

  18. Some handbook references and a summary for ''EMP engineering and design principles''

    International Nuclear Information System (INIS)

    The material in this note contains a number of handbook-oriented references and also constitutes a brief review and summary for the copyrighted publication ''EMP Engineering and Design Principles,'' a book by the Electrical Protection Department, Loop Transmission Division, Bell Telephone Laboratories, Incorporated, Whippany, New Jersey; copyrighted 1975. (WHK)

  19. Principles of Neural Network Artificial Immune System Design to Detect Attacks on Computers

    OpenAIRE

    Golovko, Vladimir; Myroslav, Komar; Sachenko, Anatoly

    2010-01-01

    It’s proposed to use artificial immune systems and neural networks to detect attacks on computer systems. The principles of attack detection system design based on artificial immune network are described, and the architecture of attack detection system is presented.

  20. First principles design of a core bioenergetic transmembrane electron-transfer protein.

    Science.gov (United States)

    Goparaju, Geetha; Fry, Bryan A; Chobot, Sarah E; Wiedman, Gregory; Moser, Christopher C; Dutton, P Leslie; Discher, Bohdana M

    2016-05-01

    Here we describe the design, Escherichia coli expression and characterization of a simplified, adaptable and functionally transparent single chain 4-α-helix transmembrane protein frame that binds multiple heme and light activatable porphyrins. Such man-made cofactor-binding oxidoreductases, designed from first principles with minimal reference to natural protein sequences, are known as maquettes. This design is an adaptable frame aiming to uncover core engineering principles governing bioenergetic transmembrane electron-transfer function and recapitulate protein archetypes proposed to represent the origins of photosynthesis. This article is part of a Special Issue entitled Biodesign for Bioenergetics--the design and engineering of electronic transfer cofactors, proteins and protein networks, edited by Ronald L. Koder and J.L. Ross Anderson. PMID:26672896

  1. Above the cloud computing: applying cloud computing principles to create an orbital services model

    Science.gov (United States)

    Straub, Jeremy; Mohammad, Atif; Berk, Josh; Nervold, Anders K.

    2013-05-01

    Large satellites and exquisite planetary missions are generally self-contained. They have, onboard, all of the computational, communications and other capabilities required to perform their designated functions. Because of this, the satellite or spacecraft carries hardware that may be utilized only a fraction of the time; however, the full cost of development and launch are still bone by the program. Small satellites do not have this luxury. Due to mass and volume constraints, they cannot afford to carry numerous pieces of barely utilized equipment or large antennas. This paper proposes a cloud-computing model for exposing satellite services in an orbital environment. Under this approach, each satellite with available capabilities broadcasts a service description for each service that it can provide (e.g., general computing capacity, DSP capabilities, specialized sensing capabilities, transmission capabilities, etc.) and its orbital elements. Consumer spacecraft retain a cache of service providers and select one utilizing decision making heuristics (e.g., suitability of performance, opportunity to transmit instructions and receive results - based on the orbits of the two craft). The two craft negotiate service provisioning (e.g., when the service can be available and for how long) based on the operating rules prioritizing use of (and allowing access to) the service on the service provider craft, based on the credentials of the consumer. Service description, negotiation and sample service performance protocols are presented. The required components of each consumer or provider spacecraft are reviewed. These include fully autonomous control capabilities (for provider craft), a lightweight orbit determination routine (to determine when consumer and provider craft can see each other and, possibly, pointing requirements for craft with directional antennas) and an authentication and resource utilization priority-based access decision making subsystem (for provider craft

  2. Design principles for high-pressure force fields: Aqueous TMAO solutions from ambient to kilobar pressures

    Science.gov (United States)

    Hölzl, Christoph; Kibies, Patrick; Imoto, Sho; Frach, Roland; Suladze, Saba; Winter, Roland; Marx, Dominik; Horinek, Dominik; Kast, Stefan M.

    2016-04-01

    Accurate force fields are one of the major pillars on which successful molecular dynamics simulations of complex biomolecular processes rest. They have been optimized for ambient conditions, whereas high-pressure simulations become increasingly important in pressure perturbation studies, using pressure as an independent thermodynamic variable. Here, we explore the design of non-polarizable force fields tailored to work well in the realm of kilobar pressures - while avoiding complete reparameterization. Our key is to first compute the pressure-induced electronic and structural response of a solute by combining an integral equation approach to include pressure effects on solvent structure with a quantum-chemical treatment of the solute within the embedded cluster reference interaction site model (EC-RISM) framework. Next, the solute's response to compression is taken into account by introducing pressure-dependence into selected parameters of a well-established force field. In our proof-of-principle study, the full machinery is applied to N,N,N-trimethylamine-N-oxide (TMAO) in water being a potent osmolyte that counteracts pressure denaturation. EC-RISM theory is shown to describe well the charge redistribution upon compression of TMAO(aq) to 10 kbar, which is then embodied in force field molecular dynamics by pressure-dependent partial charges. The performance of the high pressure force field is assessed by comparing to experimental and ab initio molecular dynamics data. Beyond its broad usefulness for designing non-polarizable force fields for extreme thermodynamic conditions, a good description of the pressure-response of solutions is highly recommended when constructing and validating polarizable force fields.

  3. The concept and principles of sustainable architectural design for national parks in Serbia

    OpenAIRE

    Milošević Predrag

    2004-01-01

    The paper elaborates the concept of sustainable architectural design that has come to the forefront in the last 20 years, and in the light of the National Park. This concept recognizes that human civilization is an integral part of the natural world and that nature must be preserved and perpetuated if the human community itself is to survive. Sustainable design articulates this idea through developments that exemplify the principles of conservation and encourage the application of those princ...

  4. The principles of designing of algorithm for speech synthesis from texts written in Albanian language

    OpenAIRE

    Agni Dika; Adnan Maxhuni; Avni Rexhepi

    2012-01-01

    The speech synthesis is artificial generation of human speech from written texts. For this purpose, adequate algorithms are designed, which then through relevant programs make it possible to synthesize texts to speech. The process of converting text into speech is also known as Text-To-Speech (TTS) system [5]. In this paper are given basic principles to be used when designing a system to synthesize speech in Albanian language from written texts. Currently there are solutions that enable natur...

  5. Human-on-a-chip design strategies and principles for physiologically based pharmocokinetics/pharmacodynamics modeling

    OpenAIRE

    Abaci, Hasan Erbil; Shuler, Michael L.

    2015-01-01

    Advances in maintaining multiple human tissues on microfluidic platforms has led to a growing interest in developing microphysiological systems for drug development studies. Determining the proper design principles and scaling rules for body-on-a-chip systems is critical for their strategic incorporation into physiologically based pharmacokinetic (PBPK)/pharmacodynamic model (PD) -aided drug development. While the need for a functional design considering organ-organ interactions has been cons...

  6. Applying Learner-Centered Principles to Teaching Human Behavior in the Social Environment in a Baccalaureate Program

    Science.gov (United States)

    Karolich, Robert; Ford, Janet

    2013-01-01

    Changes in the demographics of American undergraduate students must be addressed by changes in delivery of the curriculum. The learner-centered approach to education helps to recognize and integrate student diversity with class exercises and assignments designed to help students meet course learning outcomes. This article applies the American…

  7. High-throughput spectrometer designs in a compact form-factor: principles and applications

    Science.gov (United States)

    Norton, S. M.

    2013-05-01

    Many compact, portable Raman spectrometers have entered the market in the past few years with applications in narcotics and hazardous material identification, as well as verification applications in pharmaceuticals and security screening. Often, the required compact form-factor has forced designers to sacrifice throughput and sensitivity for portability and low-cost. We will show that a volume phase holographic (VPH)-based spectrometer design can achieve superior throughput and thus sensitivity over conventional Czerny-Turner reflective designs. We will look in depth at the factors influencing throughput and sensitivity and illustrate specific VPH-based spectrometer examples that highlight these design principles.

  8. Optimal Input Design for Aircraft Parameter Estimation using Dynamic Programming Principles

    Science.gov (United States)

    Morelli, Eugene A.; Klein, Vladislav

    1990-01-01

    A new technique was developed for designing optimal flight test inputs for aircraft parameter estimation experiments. The principles of dynamic programming were used for the design in the time domain. This approach made it possible to include realistic practical constraints on the input and output variables. A description of the new approach is presented, followed by an example for a multiple input linear model describing the lateral dynamics of a fighter aircraft. The optimal input designs produced by the new technique demonstrated improved quality and expanded capability relative to the conventional multiple input design method.

  9. Designing Social Interfaces Principles, Patterns, and Practices for Improving the User Experience

    CERN Document Server

    Crumlish, Christian

    2009-01-01

    From the creators of Yahoo!'s Design Pattern Library, Designing Social Interfaces provides you with more than 100 patterns, principles, and best practices, along with salient advice for many of the common challenges you'll face when starting a social website. Designing sites that foster user interaction and community-building is a valuable skill for web developers and designers today, but it's not that easy to understand the nuances of the social web. Now you have help. Christian Crumlish and Erin Malone share hard-won insights into what works, what doesn't, and why. You'll learn how to bala

  10. Four Principles for User Interface Design of Computerised Clinical Decision Support Systems

    DEFF Research Database (Denmark)

    Kanstrup, Anne Marie; Christiansen, Marion Berg; Nøhr, Christian

    2011-01-01

    Abstract.  The paper presents results from design of a user interface for a Computerised Clinical Decision Support System (CSSS). The ambition has been to design Human-Computer Interaction that can minimise medication errors. Through an iterative design process a digital prototype for prescriptio...... four interaction principles are integrated in the design of user interfaces for CDSS, i.e. the model is an integrated model which we suggest as a guide for interaction design when working with preventing medication errors....... of medicine has been developed. This paper presents results from the formative evaluation of the prototype conducted in a simulation laboratory with ten participating physicians. Data from the simulation is analysed by use of theory on how users perceive information. The conclusion is a model, which...... emphasises a focus on how users interact with the system, a focus on how information is provided by the system, and four principles of interaction. The four principles for design of user interfaces for CDSS are summarised as four A’s: All in one, At a glance, At hand and Attention. It is recommended that all...

  11. Applying Universal Design for Learning in Online Courses: Pedagogical and Practical Considerations

    Science.gov (United States)

    Dell, Cindy Ann; Dell, Thomas F.; Blackwell, Terry L.

    2015-01-01

    Inclusion of the universal design for learning (UDL) model as a guiding set of principles for online curriculum development in higher education is discussed. Fundamentally, UDL provides the student with multiple means of accessing the course based on three overarching principles: presentation; action and expression; and engagement and interaction.…

  12. Seismic design principles for the German fast breeder reactor SNR2

    International Nuclear Information System (INIS)

    The leading aim of a seismic design is, besides protection against seismic impacts, not to enhance the overall risk in the absence of seismic vibrations and, secondly, to avoid competition between operational needs and a seismic structural design. This approach is supported by avoiding overconservatism in the assumption of seismic loads and in the calculation of the structural response. Accordingly the seismic principles are stated as follows: restriction to German or equivalent low seismicity sites with intensities (SSE) lower VIII at frequency lower than 10-4/year; best estimate of seismic input-data without further conservatism; no consideration of OBE. The structural design principles are: 1. The secondary character of the seismic excitation is explicitly accounted for; 2. Energy absorption is allowed for by ductility of materials and construction. Accordingly strain criteria are used for failure predictions instead of stress criteria. (author). 1 fig

  13. Zebrafish housing systems: a review of basic operating principles and considerations for design and functionality.

    Science.gov (United States)

    Lawrence, Christian; Mason, Timothy

    2012-01-01

    The strategies for housing zebrafish used in biomedical research have evolved considerably over the past three decades. To keep pace with the rapid expansion and development of the zebrafish model system, the field has generally moved from keeping fish at the level of aquarium hobbyist to that of industrialized, recirculating aquaculture. Numerous commercial system vendors now offer increasingly sophisticated housing systems based on design principles that maximize the number of animals that can be housed in a given space footprint, and they are thus able to support large and diverse research programs. This review is designed to provide managers, lab animal veterinarians, investigators, and other parties responsible for care and use of these animals with a comprehensive overview of the basic operating and design principles of zebrafish housing systems. This information can be used to help plan the construction of new facilities and/or the upgrade and maintenance of existing operations. PMID:23382349

  14. Sensitivity Analysis Applied in Design of Low Energy Office Building

    DEFF Research Database (Denmark)

    Heiselberg, Per; Brohus, Henrik

    2008-01-01

    Building performance can be expressed by different indicators as primary energy use, environmental load and/or the indoor environmental quality and a building performance simulation can provide the decision maker with a quantitative measure of the extent to which an integrated design solution...... satisfies the design requirements and objectives. In the design of sustainable Buildings it is beneficial to identify the most important design parameters in order to develop more efficiently alternative design solutions or reach optimized design solutions. A sensitivity analysis makes it possible to...... identify the most important parameters in relation to building performance and to focus design and optimization of sustainable buildings on these fewer, but most important parameters. The sensitivity analyses will typically be performed at a reasonably early stage of the building design process, where it...

  15. [(18)F]-Organotrifluoroborates as Radioprosthetic Groups for PET Imaging: From Design Principles to Preclinical Applications.

    Science.gov (United States)

    Perrin, David M

    2016-07-19

    Positron emission tomography (PET) is revolutionizing our ability to visualize in vivo targets for target validation and personalized medicine. Of several classes of imaging agents, peptides afford high affinity and high specificity to distinguish pathologically distinct cell types by the presence of specific molecular targets. Of various available PET isotopes, [(18)F]-fluoride ion is preferred because of its excellent nuclear properties and on-demand production in hospitals at Curie levels. However, the short half-life of (18)F and its lack of reactivity in water continue to challenge peptide labeling. Hence, peptides are often conjugated to a metal chelator for late-stage, one-step labeling. Yet radiometals, while effective, are neither as desirable nor as available as [(18)F]-fluoride ion. Despite considerable past success in identifying semifeasible radiosyntheses, significant challenges continue to confound tracer development. These interrelated challenges relate to (1) isotope/prosthetic choice; (2) bioconjugation for high affinity; (3) high radiochemical yields, (4) specific activities of >1 Ci/μmol to meet FDA microdose requirements; and (5) rapid clearance and in vivo stability. These enduring challenges have been extensively highlighted, while a single-step, operationally simple, and generally applicable means of labeling a peptide with [(18)F]-fluoride ion in good yield and high specific activity has eluded radiochemists and nuclear medicine practitioners for decades. Radiosynthetic ease is of primordial importance since multistep labeling reactions challenge clinical tracer production. In the past decade, as we sought to meet this challenge, appreciation of reactions with aqueous fluoride led us to consider organotrifluoroborate (RBF3(-)) synthesis as a means of rapid aqueous peptide labeling. We have applied principles of mechanistic chemistry, knowledge of chemical reactivity, and synthetic chemistry to design stable RBF3(-)s. Over the past 10 years

  16. VHDL basics applied design by SIPAC qualification system

    International Nuclear Information System (INIS)

    This book has six chapters, which are about Flowrian of SIPAC qualification system including internet CAD system and remote server service, logic circuit on design and qualification of device such as gate circuit, multiplex and decoder, order logic circuit with D type flip-flop design and qualification and Rom and RAM's design and qualification, finite state machine such as odd checker, sequence detector, test clock generator and traffic light controller, design and qualification about data path, design of application circuit. It has two appendixes on install and the way to use SIPAC qualification system and remote service for SIPAC qualification system.

  17. The principle of complementarity in the design of reserve networks to conserve biodiversity: a preliminary history

    Indian Academy of Sciences (India)

    James Justus; Sahotra Sarkar

    2002-07-01

    Explicit, quantitative procedures for identifying biodiversity priority areas are replacing the often ad hoc procedures used in the past to design networks of reserves to conserve biodiversity. This change facilitates more informed choices by policy makers, and thereby makes possible greater satisfaction of conservation goals with increased efficiency. A key feature of these procedures is the use of the principle of complementarity, which ensures that areas chosen for inclusion in a reserve network complement those already selected. This paper sketches the historical development of the principle of complementarity and its applications in practical policy decisions. In the first section a brief account is given of the circumstances out of which concerns for more explicit systematic methods for the assessment of the conservation value of different areas arose. The second section details the emergence of the principle of complementarity in four independent contexts. The third section consists of case studies of the use of the principle of complementarity to make practical policy decisions in Australasia, Africa, and America. In the last section, an assessment is made of the extent to which the principle of complementarity transformed the practice of conservation biology by introducing new standards of rigor and explicitness.

  18. The Principles and Process of Materials Design:A case study

    Institute of Scientific and Technical Information of China (English)

    苏艺

    2004-01-01

    Designing materials for one's own class is part of most EFL teachers' experience and some even have the opportunity to prepare materials for a wider readership but how many of these writers have studied the principles and process of material design? In the following account a teacher from Guangdong Province, China reports on her preparation of an English language course before she had read anything on the topic. She interweaves this account with reflections following her later study of materials design during postgraduate studies in New Zealand. She makes comparisons and contrasts between what she did in practice and the theories she later read about.

  19. Applying operating experience to design the CANDU 3 process

    International Nuclear Information System (INIS)

    The CANDU 3 is an advanced, smaller (450 MWe), standardized version of the CANDU now being designed for service later in the decade and beyond. The design of this evolutionary nuclear power plant has been carefully planned and organized to gain maximum benefits from new technologies and from world experience to date in designing, building, commissioning and operating nuclear power stations. The good performance record of existing CANDU reactors makes consideration of operating experience from these plants a particularly vital component of the design process. Since the completion of the first four CANDU 6 stations in the early 1980s, and with the continuing evolution of the multi-unit CANDU station designs since then, AECL CANDU has devised several processes to ensure that such feedback is made available to designers. An important step was made in 1986 when a task force was set up to review and process ideas arising from the commissioning and early operation of the CANDU 6 reactors which were, by that time, operating successfully in Argentina and Korea, as well as the Canadian provinces of Quebec and New Brunswick. The task force issued a comprehensive report which, although aimed at the design of an improved CANDU 6 station, was made available to the CANDU 3 team. By that time also, the Institute of Power Operations (INPO) in the U.S., of which AECL is a Supplier Participant member, was starting to publish Good Practices and Guidelines related to the review and the use of operating experiences. In addition, details of significant events were being made available via the INPO SEE-IN (Significant Event Evaluation and Information Network) Program, and subsequently the CANNET network of the CANDU Owners' Group (COG). Systematic review was thus possible by designers of operations reports, significant event reports, and related documents in a continuing program of design improvement. Another method of incorporating operations feedback is to involve experienced utility

  20. Modeling Organizational Design - Applying A Formalism Model From Theoretical Physics

    OpenAIRE

    Robert Fabac; Josip Stepanić

    2008-01-01

    Modern organizations are exposed to diverse external environment influences. Currently accepted concepts of organizational design take into account structure, its interaction with strategy, processes, people, etc. Organization design and planning aims to align this key organizational design variables. At the higher conceptual level, however, completely satisfactory formulation for this alignment doesn’t exist. We develop an approach originating from the application of concepts of theoretical ...

  1. Human-on-a-chip design strategies and principles for physiologically based pharmacokinetics/pharmacodynamics modeling.

    Science.gov (United States)

    Abaci, Hasan Erbil; Shuler, Michael L

    2015-04-01

    Advances in maintaining multiple human tissues on microfluidic platforms has led to a growing interest in the development of microphysiological systems for drug development studies. Determination of the proper design principles and scaling rules for body-on-a-chip systems is critical for their strategic incorporation into physiologically based pharmacokinetic (PBPK)/pharmacodynamic (PD) model-aided drug development. While the need for a functional design considering organ-organ interactions has been considered, robust design criteria and steps to build such systems have not yet been defined mathematically. In this paper, we first discuss strategies for incorporating body-on-a-chip technology into the current PBPK modeling-based drug discovery to provide a conceptual model. We propose two types of platforms that can be involved in the different stages of PBPK modeling and drug development; these are μOrgans-on-a-chip and μHuman-on-a-chip. Then we establish the design principles for both types of systems and develop parametric design equations that can be used to determine dimensions and operating conditions. In addition, we discuss the availability of the critical parameters required to satisfy the design criteria, consider possible limitations for estimating such parameter values and propose strategies to address such limitations. This paper is intended to be a useful guide to the researchers focused on the design of microphysiological platforms for PBPK/PD based drug discovery. PMID:25739725

  2. Designing Sustainable IT System – From the Perspective of Universal Design Principles

    OpenAIRE

    Mustaquim, Moyen; Nyström, Tobias

    2013-01-01

    Since the concept of universal design is already extending the boundary of disabilities, it is significant to include different aspects of information technology where universal design enabled efforts can contribute towards better designed systems, products and services. Sustainability is an important and growing public concern in today’s world. Nevertheless, attempts of designing IT system that can be called sustainable in nature are not so evident at present. In this paper we propose a fram...

  3. Modeling Organizational Design - Applying A Formalism Model From Theoretical Physics

    Directory of Open Access Journals (Sweden)

    Robert Fabac

    2008-06-01

    Full Text Available Modern organizations are exposed to diverse external environment influences. Currently accepted concepts of organizational design take into account structure, its interaction with strategy, processes, people, etc. Organization design and planning aims to align this key organizational design variables. At the higher conceptual level, however, completely satisfactory formulation for this alignment doesn’t exist. We develop an approach originating from the application of concepts of theoretical physics to social systems. Under this approach, the allocation of organizational resources is analyzed in terms of social entropy, social free energy and social temperature. This allows us to formalize the dynamic relationship between organizational design variables. In this paper we relate this model to Galbraith's Star Model and we also suggest improvements in the procedure of the complex analytical method in organizational design.

  4. Applying learning theories and instructional design models for effective instruction.

    Science.gov (United States)

    Khalil, Mohammed K; Elkhider, Ihsan A

    2016-06-01

    Faculty members in higher education are involved in many instructional design activities without formal training in learning theories and the science of instruction. Learning theories provide the foundation for the selection of instructional strategies and allow for reliable prediction of their effectiveness. To achieve effective learning outcomes, the science of instruction and instructional design models are used to guide the development of instructional design strategies that elicit appropriate cognitive processes. Here, the major learning theories are discussed and selected examples of instructional design models are explained. The main objective of this article is to present the science of learning and instruction as theoretical evidence for the design and delivery of instructional materials. In addition, this article provides a practical framework for implementing those theories in the classroom and laboratory. PMID:27068989

  5. Self-Adaptive Stepsize Search Applied to Optimal Structural Design

    Science.gov (United States)

    Nolle, L.; Bland, J. A.

    Structural engineering often involves the design of space frames that are required to resist predefined external forces without exhibiting plastic deformation. The weight of the structure and hence the weight of its constituent members has to be as low as possible for economical reasons without violating any of the load constraints. Design spaces are usually vast and the computational costs for analyzing a single design are usually high. Therefore, not every possible design can be evaluated for real-world problems. In this work, a standard structural design problem, the 25-bar problem, has been solved using self-adaptive stepsize search (SASS), a relatively new search heuristic. This algorithm has only one control parameter and therefore overcomes the drawback of modern search heuristics, i.e. the need to first find a set of optimum control parameter settings for the problem at hand. In this work, SASS outperforms simulated-annealing, genetic algorithms, tabu search and ant colony optimization.

  6. Study on sodium viewing technique applying sodium gamma-rays emission tomography. Verification of basic principle by analytical investigation

    International Nuclear Information System (INIS)

    To confirm structural integrity of a primary cooling system and in-vessel components in a sodium-cooled fast breeder reactor, monitoring and inspection technique applying Gamma-rays emitted from sodium are proposed. The basic principle is as follows. As radioisotope 24Na decays, photons are emitted and a fraction of these photons penetrate materials. If the number of these photons is counted by radiation detectors, an image of gamma-rays source is reconstructed by a computed tomography technique. In this report, Applicability and problems concerned with the technique are investigated. Main results are as follows: (1) To verify applicability, the technique was analytically investigated based on gamma-rays emitted from sodium coolant in a typical pipe of a primary cooling system. As a result, it was confirmed that the image of gamma-rays source could be reconstructed. (2) A required time to measure in a spatial resolution of about 1mm was investigated in the detection efficiency of 20%. The time was about 4 minutes per section by a thousand detectors in the typical pipe of a primary cooling system. And in a typical steam generator, the time was about 2 days per section by ten thousand detectors. (3) To realize a fluoroscopic inspection system, it is necessary that the principle should be verified by experimental researches. Main equipments of the system are a collimator, radiation detector, scanner, signal processing device and image processing device. As a spatial resolution is decide by the collimator, the shape must be evaluated by experimental researches and analytical investigation. (author)

  7. Using of object-oriented design principles in electric machines development

    OpenAIRE

    N.N. ZABLODSKII; V.E. Pliugin; A.N. Petrenko

    2016-01-01

    Purpose. To develop the theoretical basis of electrical machines object-oriented design, mathematical models and software to improve their design synthesis, analysis and optimization. Methodology. We have applied object-oriented design theory in electric machines optimal design and mathematical modelling of electromagnetic transients and electromagnetic field distribution. We have correlated the simulated results with the experimental data obtained by means of the double-stator screw dryer wi...

  8. On extracting design principles from biology: I. Method-General answers to high-level design questions for bioinspired robots.

    Science.gov (United States)

    Haberland, M; Kim, S

    2015-01-01

    When millions of years of evolution suggest a particular design solution, we may be tempted to abandon traditional design methods and copy the biological example. However, biological solutions do not often translate directly into the engineering domain, and even when they do, copying eliminates the opportunity to improve. A better approach is to extract design principles relevant to the task of interest, incorporate them in engineering designs, and vet these candidates against others. This paper presents the first general framework for determining whether biologically inspired relationships between design input variables and output objectives and constraints are applicable to a variety of engineering systems. Using optimization and statistics to generalize the results beyond a particular system, the framework overcomes shortcomings observed of ad hoc methods, particularly those used in the challenging study of legged locomotion. The utility of the framework is demonstrated in a case study of the relative running efficiency of rotary-kneed and telescoping-legged robots. PMID:25643176

  9. On extracting design principles from biology: I. Method–General answers to high-level design questions for bioinspired robots

    International Nuclear Information System (INIS)

    When millions of years of evolution suggest a particular design solution, we may be tempted to abandon traditional design methods and copy the biological example. However, biological solutions do not often translate directly into the engineering domain, and even when they do, copying eliminates the opportunity to improve. A better approach is to extract design principles relevant to the task of interest, incorporate them in engineering designs, and vet these candidates against others. This paper presents the first general framework for determining whether biologically inspired relationships between design input variables and output objectives and constraints are applicable to a variety of engineering systems. Using optimization and statistics to generalize the results beyond a particular system, the framework overcomes shortcomings observed of ad hoc methods, particularly those used in the challenging study of legged locomotion. The utility of the framework is demonstrated in a case study of the relative running efficiency of rotary-kneed and telescoping-legged robots. (paper)

  10. Basic Principles of Industrial Electric Power Network Computer Aided Design and Engineering

    Directory of Open Access Journals (Sweden)

    M. Fursanov

    2012-01-01

    Full Text Available A conceptual model for a computer aided design and engineering system has been developed in the paper. The paper presents basic automation process principles including a graphical representation   network and calculation results, convenient user interface, automatic mode calculation, selection of transformer rated power and cross-section area of wires. The developed algorithm and program make it possible to save time and improve quality of project implementation.

  11. Designing Landscapes for Performance Based on Emerging Principles in Landscape Ecology

    OpenAIRE

    Douglas M. Johnston; Sarah Taylor Lovell

    2009-01-01

    We have proposed a framework for transforming landscapes to improve performance by integrating ecological principles into landscape design. This effort would focus on the development of multifunctional landscapes, guided by the rapidly growing knowledge base of ecosystem services provided by landscape features. Although the conventional approach to landscape ecology is based on a model that assumes poor ecological quality in the human-dominated matrix, a review of recent literature reveals im...

  12. Design principle for increasing charge mobility of π-conjugated polymers using regularly localized molecular orbitals

    OpenAIRE

    Terao, Jun; Wadahama, Akihisa; Matono, Akitoshi; Tada, Tomofumi; Watanabe, Satoshi; Seki, Shu; Fujihara, Tetsuaki; Tsuji, Yasushi

    2013-01-01

    The feasibility of using π-conjugated polymers as next-generation electronic materials is extensively studied; however, their charge mobilities are lower than those of inorganic materials. Here we demonstrate a new design principle for increasing the intramolecular charge mobility of π-conjugated polymers by covering the π-conjugated chain with macrocycles and regularly localizing π-molecular orbitals to realize an ideal orbital alignment for charge hopping. Based on theoretical predictions, ...

  13. Jūrmala City Public Transport Compliance with the Universal Design Principles

    OpenAIRE

    Vīksniņa, Ina; Vītoliņa, Kristīne; Priede, Līga; Ozola, Ina; Erkena, Dace

    2015-01-01

    Integration of humans into society as the full members of it is to take active part in social activities, but not for all people it is possible due to physical barriers that limit integration. People, who are facing different environment related obstacles - integration problems, are people with disabilities, elderly, mothers with small children and prams. Successful integration is based on adapted environment that is based on principles of the universal design. Public transport is an importan...

  14. Supply Chain Design and Control Principles in Local Food Production: A Norwegian Case Study

    OpenAIRE

    Dreyer, Heidi C.; Strandhagen, Jan Ola; Thomassen, Maria K.; Romsdal, Anita; Gran, Erik

    2014-01-01

    Based on an analysis of four local food producers this paper explores the relation between the supply chain design and control principles, and the strategic fit. Local food has arisen as a popular supplement to the traditional supermarket product range offered by retailers and restaurants. However it has been shown that local food struggles with the market access, and that the supply chain is one of the obstacles preventing local food producers to gain a solid market position. We analyse how ...

  15. Designing for the Internet of Things : models and principles for application-augmented products.

    OpenAIRE

    Thebault, Pierrick

    2013-01-01

    The Internet of Things, whose underlying vision and technologies aim at bridging the physical and digital worlds together, lead to the creation of new types of applications coupling Web services with everyday products. Such product-oriented applications, which enable the functional exposition, control or enhancement of artifacts that embed information processing capabilities, question the established design principles and conventions. They open up the possibility for Internet-enabled products...

  16. Zebrafish Housing Systems: A Review of Basic Operating Principles and Considerations for Design and Functionality

    OpenAIRE

    Lawrence, Christian; Mason, Timothy

    2012-01-01

    The strategies for housing zebrafish used in biomedical research have evolved considerably over the past three decades. To keep pace with the rapid expansion and development of the zebrafish model system, the field has generally moved from keeping fish at the level of aquarium hobbyist to that of industrialized, recirculating aquaculture. Numerous commercial system vendors now offer increasingly sophisticated housing systems based on design principles that maximize the number of animals that ...

  17. THE PRINCIPLE OF REASONED SHAPE FORMING AS A BASIS FOR PLASTIC ADEQUACY OF DESIGN OBJECTS

    Directory of Open Access Journals (Sweden)

    Vitaly Vasilyevich Miroshnikov

    2015-08-01

    Full Text Available The article highlights the basic approaches to configuring the form in design. The authors analyze the main strategies of shape formation in modern design practices. The novelty of the subject is that the analysis is carried out in the context of the adequacy of the design of plastic objects. The essence of the problems outlined by the authors is inconsistency between the object’s semantics and its external form resulted from incorrect practices of shape formation. Consideration of strategies and tactics of configuration of forms is based on comparison of two principles of shape formation - intuitive and discursive. The aim of the authors is to identify the reasons and structural specificity of intuitive and discursive practices of shape formation in design and to show the priority of the discursive approach. Attention of the authors is focused on the differences of search algorithms and results of shaping which are characteristic for the principles under consideration. The arguments cited in the article determine the discursive strategy of form configuration as the most correct and efficient in terms of design engineering. In the process of analyzing the basic algorithms of shape formation, of topical importance is the concept of legitimacy of form as a definition of the most appropriate process and a results of the project research. The article gives the interpretation of legitimacy in terms of the project practices and design - education.

  18. Development of safety principles for the design of future nuclear power plants

    International Nuclear Information System (INIS)

    The main purpose of this TECDOC is to propose updates to existing safety principles which could be used as a basis for developing safety principles for the design of future NPPs. Accordingly, this document is intended to be useful to reactor designers, owners, operators, researchers and regulators. It is also expected that this document can contribute to international harmonization of safety approaches, and that it will help ensure that future reactors will be designed worldwide to a high standard of safety. As such, these proposed updates are intended to provide general guidance which, if carefully and properly implemented, will result in reactor designs with enhanced safety characteristics beyond those currently in operation. This enhancement results from the fact that the proposals are derived from the lessons learned from more recent operational experience, R and D, design, testing, and analysis developed over the past decade or so, as well as from attempts to reflect the current trends in reactor design, such as the introduction of new technologies. 8 refs, 3 figs

  19. Structural principles for computational and de novo design of 4Fe-4S metalloproteins.

    Science.gov (United States)

    Nanda, Vikas; Senn, Stefan; Pike, Douglas H; Rodriguez-Granillo, Agustina; Hansen, Will A; Khare, Sagar D; Noy, Dror

    2016-05-01

    Iron-sulfur centers in metalloproteins can access multiple oxidation states over a broad range of potentials, allowing them to participate in a variety of electron transfer reactions and serving as catalysts for high-energy redox processes. The nitrogenase FeMoCO cluster converts di-nitrogen to ammonia in an eight-electron transfer step. The 2(Fe4S4) containing bacterial ferredoxin is an evolutionarily ancient metalloprotein fold and is thought to be a primordial progenitor of extant oxidoreductases. Controlling chemical transformations mediated by iron-sulfur centers such as nitrogen fixation, hydrogen production as well as electron transfer reactions involved in photosynthesis are of tremendous importance for sustainable chemistry and energy production initiatives. As such, there is significant interest in the design of iron-sulfur proteins as minimal models to gain fundamental understanding of complex natural systems and as lead-molecules for industrial and energy applications. Herein, we discuss salient structural characteristics of natural iron-sulfur proteins and how they guide principles for design. Model structures of past designs are analyzed in the context of these principles and potential directions for enhanced designs are presented, and new areas of iron-sulfur protein design are proposed. This article is part of a Special issue entitled Biodesign for Bioenergetics - the design and engineering of electronic transfer cofactors, protein networks, edited by Ronald L. Koder and J.L Ross Anderson. PMID:26449207

  20. Using articulation and inscription as catalysts for reflection: Design principles for reflective inquiry

    Science.gov (United States)

    Loh, Ben Tun-Bin

    2003-07-01

    The demand for students to engage in complex student-driven and information-rich inquiry investigations poses challenges to existing learning environments. Students are not familiar with this style of work, and lack the skills, tools, and expectations it demands, often forging blindly forward in the investigation. If students are to be successful, they need to learn to be reflective inquirers, periodically stepping back from an investigation to evaluate their work. The fundamental goal of my dissertation is to understand how to design learning environments to promote and support reflective inquiry. I have three basic research questions: how to define this mode of work, how to help students learn it, and understanding how it facilitates reflection when enacted in a classroom. I take an exploratory approach in which, through iterative cycles of design, development, and reflection, I develop principles of design for reflective inquiry, instantiate those principles in the design of a software environment, and test that software in the context of classroom work. My work contributes to the understanding of reflective inquiry in three ways: First, I define a task model that describes the kinds of operations (cognitive tasks) that students should engage in as reflective inquirers. These operations are defined in terms of two basic tasks: articulation and inscription, which serve as catalysts for externalizing student thinking as objects of and triggers for reflection. Second, I instantiate the task model in the design of software tools (the Progress Portfolio). And, through proof of concept pilot studies, I examine how the task model and tools helped students with their investigative classroom work. Finally, I take a step back from these implementations and articulate general design principles for reflective inquiry with the goal of informing the design of other reflective inquiry learning environments. There are three design principles: (1) Provide a designated work space

  1. Applying and incorporating user driven innovation when designing concepts

    DEFF Research Database (Denmark)

    Thorp Hansen, Claus; Brønnum, Louise

    . This paper is based on practical experience working with theoretical concept frameworks, which have induced new perspectives in a reframing. We will account for the concept design process and why a reframing is called for when working with user research, leading to a proposal for new dimensions to the......This paper addresses the difficulties seen when working within the user driven innovation [UDI] paradigm. We examine some of the circumstances that often make it difficult to work with user insights in concept design. UDI has become a recognized design approach, but has not yet accommodated a...... design practice explicitly considering the type of user insights this approach implies. For that reason UDI has yet to prove itself and its potential effect; a study of Danish initiative “program for user driven innovation” has shown little effect in this regard. However it has shown that radical new...

  2. Designing IS Curricula for Practical Relevance: Applying Baseball's "Moneyball" Theory

    Science.gov (United States)

    Surendra, Nanda C.; Denton, James W.

    2009-01-01

    Baseball's "Moneyball" theory states that the baseball market undervalues some attributes (and players with these attributes) that are key contributors to wins while overvaluing other attributes. Teams who correctly evaluate attributes that contribute to wins have higher winning percentages with relatively low payrolls. We applied the Moneyball…

  3. Applying axiomatic design to a medication distribution system

    Science.gov (United States)

    Raguini, Pepito B.

    As the need to minimize medication errors drives many medical facilities to come up with robust solutions to the most common error that affects patient's safety, these hospitals would be wise to put a concerted effort into finding methodologies that can facilitate an optimized medical distribution system. If the hospitals' upper management is looking for an optimization method that is an ideal fit, it is just as important that the right tool be selected for the application at hand. In the present work, we propose the application of Axiomatic Design (AD), which is a process that focuses on the generation and selection of functional requirements to meet the customer needs for product and/or process design. The appeal of the axiomatic approach is to provide both a formal design process and a set of technical coefficients for meeting the customer's needs. Thus, AD offers a strategy for the effective integration of people, design methods, design tools and design data. Therefore, we propose the AD methodology to medical applications with the main objective of allowing nurses the opportunity to provide cost effective delivery of medications to inpatients, thereby improving quality patient care. The AD methodology will be implemented through the use of focused stores, where medications can be readily stored and can be conveniently located near patients, as well as a mobile apparatus that can also store medications and is commonly used by hospitals, the medication cart. Moreover, a robust methodology called the focused store methodology will be introduced and developed for both the uncapacitated and capacitated case studies, which will set up an appropriate AD framework and design problem for a medication distribution case study.

  4. Code of practice and design principles for portable and transportable radiological protection systems

    International Nuclear Information System (INIS)

    The Code of Practice and design principles for portable and transportable radiological protection systems are presented in three parts. Part 1 specifies the requirement for Radiological Protection Instrumentation (RPI) including operational characteristics and the effects of both a radiation and non-radiation environment. Part 2 satisfies the requirement for RPI equipment as regards the overall design, the availability, the reliability, the information display, the human factors, the power supplies, the manufacture and quality assurance, the testing and the cost. Part 3 deals with the supply, location and operation of the RPI equipment. (U.K.)

  5. New class of planar ferroelectric Mott insulators via first-principles design

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Chanul; Park, Hyowon; Marianetti, Chris A.

    2015-12-11

    which is not common in known materials. Here we use first-principles calculations to design layered double perovskite oxides AABBO6 which achieve the aforementioned properties in the context of Mott insulators. In our design rules, the gap is dictated by B/B electronegativity difference in a Mott state, while the polarization is obtained via nominal d0 filling on the B-site, A-type cations bearing lone-pair electrons, and A = A size mismatch. Successful execution is demonstrated in BaBiCuVO6, BaBiNiVO6, BaLaCuVO6, and PbLaCuVO6.

  6. Commutation possibilities of reverse-connected dynistors and principles of RCD-circuit design (review)

    International Nuclear Information System (INIS)

    One generalized the results of investigation into the reverse-connected dynistors (RCD) designed for pulsed and conversion equipment high-power facilities. Paper describes the basic design principles for high-power RCD-switches and the base circuits of pulsed and high-frequency facilities based on RCD. Paper contains the results of tests of high-voltage microsecond and submicrosecond RCD-generators with 108-1010 W pulse intensity and of high-frequency RCD-inverters with 104-105 W average intensity

  7. Control room philosophy: Principles of control room design and control room work

    International Nuclear Information System (INIS)

    In order to provide insights for improvement of work in control rooms several factors have to be considered. Knowledge of principles including control room philosophies will guide the recommended improvements. In addition to knowledge about specific principles an advantage for an organization can be an understanding of similarities and policies used in other high risk industry. The report has been developed on the basis of a document analysis of international standards and other guiding documents. (NUREG 0711, ISO 11064, ISO 6385, IEC 60964). In addition to the document analysis which has strived to compare the documents to see similarities in important principals, experience from working with control room design, modifications and evaluations in other high risk industries has pervaded the report. Important principles have been identified which are recommended to be included in a control room philosophy. Many of these are similar to the principles identified in the international standards. An additional principal which is regarded as important is the utilization of Key Performance Indicators (KPI) which can be used as a measure to target preventative means. Further more it is critical that the control room philosophy is easy to access and comprehend for all users. One of the challenges that remain after having developed a control room philosophy is how to utilize it in the daily work situation. It is vital that the document remains as a living document, guiding the continual improvement of the control room in the various life cycle stages

  8. APPLIED KNOWLEDGE MANAGEMENT IN SMALL DESIGN FIRMS: CASE STUDY

    Directory of Open Access Journals (Sweden)

    Christian Donin

    2016-09-01

    Full Text Available Knowledge is the new strategic imperative of organizations. The ability to manage knowledge is a crucial part of any organizations operational processes. The creation and diffusion of knowledge have become ever more important factors in competitiveness. This paper investigates the Knowledge Management and flow information and in small design firms. It is divided into three main parts. The first part of this paper describes the importance of Knowledge Management for organizations are described together with responsibilities needed to ensure successful Knowledge Management implementations and the Spiral of Organizational Knowledge Creation conception. The second part approaches literature available about process and organizational structure and information flow related to Brazilian design firms. Finally, this paper presents a case study of small design office of Civil Engineering identifying organizational process, verifying the types of communication practices and identifying the types of dynamic process of The Spiral of Organizational Knowledge Creation, KM strategy and dynamic through Knowledge Transfer.

  9. Applying design of experiments to a compression refrigeration cycle

    Directory of Open Access Journals (Sweden)

    Nuno Ricardo Costa

    2015-12-01

    Full Text Available Refrigeration cycles are used in a large diversity of industrial and domestic (residential and non-residential equipment and their efficiency depend on several variables. To better understanding of how controllable variables impact on a compression refrigeration cycle efficiency, statistically designed experiments were conducted and data were analyzed. A quadratic polynomial model was fitted to Coefficient of Performance and variable settings to maximize cycle efficiency identified. Results give confidence to use the illustrated approach for refrigeration cycle design and operation improvement purposes.

  10. Designing health care environments: Part I. Basic concepts, principles, and issues related to evidence-based design.

    Science.gov (United States)

    Cesario, Sandra K

    2009-06-01

    A 2001 Institute of Medicine report captured the nation's attention regarding the dangers that can result from the health care environment. This report, fueled by the need for new facilities to be constructed, led to an explosion of research that now links the physical structure and design of health care facilities to the health and well-being of patients, nurses, other health care workers, and visitors. Continuing nursing education that highlights the importance of evidence-based design has been associated with measurable improvement in health care facilities' clinical outcomes, economic performance, employee productivity, customer satisfaction, and cultural congruency. Three major categories of outcomes can be impacted by evidence-based design: stress reduction, safety, and overall health care quality and ecology. In this article, Part I of a two-part series, the basic concepts, principles, and issues related to evidence-based design are introduced. Part II will describe continuing education programs available for nurses. PMID:19639918

  11. A Probabilistic Design Method Applied to Smart Composite Structures

    Science.gov (United States)

    Shiao, Michael C.; Chamis, Christos C.

    1995-01-01

    A probabilistic design method is described and demonstrated using a smart composite wing. Probabilistic structural design incorporates naturally occurring uncertainties including those in constituent (fiber/matrix) material properties, fabrication variables, structure geometry and control-related parameters. Probabilistic sensitivity factors are computed to identify those parameters that have a great influence on a specific structural reliability. Two performance criteria are used to demonstrate this design methodology. The first criterion requires that the actuated angle at the wing tip be bounded by upper and lower limits at a specified reliability. The second criterion requires that the probability of ply damage due to random impact load be smaller than an assigned value. When the relationship between reliability improvement and the sensitivity factors is assessed, the results show that a reduction in the scatter of the random variable with the largest sensitivity factor (absolute value) provides the lowest failure probability. An increase in the mean of the random variable with a negative sensitivity factor will reduce the failure probability. Therefore, the design can be improved by controlling or selecting distribution parameters associated with random variables. This can be implemented during the manufacturing process to obtain maximum benefit with minimum alterations.

  12. Applying Learning Theories and Instructional Design Models for Effective Instruction

    Science.gov (United States)

    Khalil, Mohammed K.; Elkhider, Ihsan A.

    2016-01-01

    Faculty members in higher education are involved in many instructional design activities without formal training in learning theories and the science of instruction. Learning theories provide the foundation for the selection of instructional strategies and allow for reliable prediction of their effectiveness. To achieve effective learning…

  13. Preliminary design enhancement by incorporating set- based design principles and a navigator

    OpenAIRE

    Dobrovolskyte, Nora

    2015-01-01

    The need for improvement of Product Development (PD) processes has been demonstrated by a high demand for the aerospace products to be developed quicker and cheaper. Set-Based Design (SBD) can improve the ability to respond faster to customers’ requirements by developing a set of design solutions for possible future product orders in parallel. In SBD participants practise SBCE (Set-Based Concurrent Engineering) by reasoning, developing and communicating about sets of solutions ...

  14. Designing an Educational Game:Design Principles from a Holistic Perspective

    OpenAIRE

    Bjørner, Thomas; Hansen, Charina Benedikte Søgaard

    2010-01-01

    When designing games with learning purposes used in a classroom, there often occur problems about the lack of learning content or the lack of game contents. Other disadvantages of existing educational games are the difficulty to provide a continual balance between the challenge and the pupils’ skill to control and solve the given task. In this paper we suggest three different perspectives that need to be communicated across in order to design a useful educational game: teachers, pupils and ga...

  15. Applying the Five-Factor Model to Game Design

    OpenAIRE

    Bildtgård, Marcus

    2014-01-01

    What makes us like or dislike certain games? Is there relation between our tastes in games and our personalities and can it be measured? This dissertation examines gamer personalities and game attributes with the help of the Five-Factor Model, also called The Big Five. It treats an experiment on how to apply the Five-Factor Model to games and their players and what it may be used for. By interviewing gamers, recording their favored and unfavored games, letting the gamers take a Big Five perso...

  16. Applying design of experiments to a compression refrigeration cycle

    OpenAIRE

    Nuno Ricardo Costa; João Garcia

    2015-01-01

    Refrigeration cycles are used in a large diversity of industrial and domestic (residential and non-residential) equipment and their efficiency depend on several variables. To better understanding of how controllable variables impact on a compression refrigeration cycle efficiency, statistically designed experiments were conducted and data were analyzed. A quadratic polynomial model was fitted to Coefficient of Performance and variable settings to maximize cycle efficiency identified. Results ...

  17. A GOMS model applied to a simplified control panel design

    International Nuclear Information System (INIS)

    The design of the user interface for a new system requires many decisions to be considered. To develop sensitivity to user needs requires understanding user behavior. The how-to-do-it knowledge is a mixture of task-related and interface-related components. A conscientious analysis of these components, allows the designer to construct a model in terms of goals, operators, methods, and selection (GOMS model) rules that can be advantageously used in the design process and evaluation of a user interface. The emphasis of the present work is on describing the importance and use of a GOMS model as a formal user interface analysis tool in the development of a simplified panel for the control of a nuclear power plant. At Pennsylvania State University, a highly automated control system with a greatly simplified human interface has been proposed to improve power plant safety. Supervisory control is to be conducted with a simplified control panel with the following functions: startup, shutdown, increase power, decrease power, reset, and scram. Initial programming of the operator interface has been initiated within the framework of a U.S. Department of Energy funded university project for intelligent distributed control. A hypothesis to be tested is that this scheme can be also used to estimate mental work load content and predict human performance

  18. [Information and communication technologies in teaching applied and experimental designs].

    Science.gov (United States)

    Bono, Roser; Arnau, Jaume; Blanca, María J

    2006-08-01

    In this work, an innovative teaching model applied to methodological contents in psychology is presented. The proposed didactic model includes Information and Communication Technologies (ICT), such as CD-ROMs, web sites and Internet. These resources complement class attendance. In the classes the students are informed, guided and oriented so that they are able to obtain information and reorganize it in a coherent way. The aim of this article is to find out the students' learning preferences and estimate the incorporation of ICT, by means of the ETIM (Evaluation of Teaching Innovation Model) questionnaire. The results show that the students are aware of the need to consult other materials and that ICT helps students to understand the subject from various perspectives. In this way, the students become more autonomous in acquiring learning results. PMID:17296099

  19. Designing Crane Controls with applied Mechanical and Electrical Safety Features

    Science.gov (United States)

    Lytle, Bradford P.; Walczak, Thomas A.; Delgado, H. (Technical Monitor)

    2002-01-01

    The use of overhead traveling bridge cranes in many varied applications is common practice. In particular, the use of cranes in the nuclear, military, commercial, aerospace, and other industries can involve safety critical situations. Considerations for Human Injury or Casualty, Loss of Assets, Endangering the Environment, or Economic Reduction must be addressed. Traditionally, in order to achieve additional safety in these applications, mechanical systems have been augmented with a variety of devices. These devices assure that a mechanical component failure shall reduce the risk of a catastrophic loss of the correct and/or safe load carrying capability. ASME NOG-1-1998, (Rules for Construction of Overhead and Gantry Cranes, Top Running Bridge, and Multiple Girder), provides design standards for cranes in safety critical areas. Over and above the minimum safety requirements of todays design standards, users struggle with obtaining a higher degree of reliability through more precise functional specifications while attempting to provide "smart" safety systems. Electrical control systems also may be equipped with protective devices similar to the mechanical design features. Demands for improvement of the cranes "control system" is often recognized, but difficult to quantify for this traditionally "mechanically" oriented market. Finite details for each operation must be examined and understood. As an example, load drift (or small motions) at close tolerances can be unacceptable (and considered critical). To meet these high functional demands encoders and other devices are independently added to control systems to provide motion and velocity feedback to the control drive. This paper will examine the implementation of Programmable Electronic Systems (PES). PES is a term this paper will use to describe any control system utilizing any programmable electronic device such as Programmable Logic Controllers (PLC), or an Adjustable Frequency Drive (AID) 'smart' programmable

  20. Applying UML and MDA to Real Systems Design

    CERN Document Server

    Oliver, Ian

    2011-01-01

    Traditionally system design has been made from a black box/functionality only perspective which forces the developer to concentrate on how the functionality can be decomposed and recomposed into so called components. While this technique is well established and well known it does suffer fromsome drawbacks; namely that the systems produced can often be forced into certain, incompatible architectures, difficult to maintain or reuse and the code itself difficult to debug. Now that ideas such as the OMG's Model Based Architecture (MDA) or Model Based Engineering (MBE) and the ubiquitous modelling language UML are being used (allegedly) and desired we face a number of challenges to existing techniques.

  1. Geo-environmental mapping tool applied to pipeline design

    Energy Technology Data Exchange (ETDEWEB)

    Andrade, Karina de S.; Calle, Jose A.; Gil, Euzebio J. [Geomecanica S/A Tecnologia de Solo Rochas e Materiais, Rio de Janeiro, RJ (Brazil); Sare, Alexandre R. [Geomechanics International Inc., Houston, TX (United States); Soares, Ana Cecilia [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil)

    2009-07-01

    The Geo-Environmental Mapping is an improvement of the Geological-Geotechnical Mapping used for basic pipeline designs. The main purpose is to assembly the environmental, geotechnical and geological concepts in a methodological tool capable to predict constrains and reduce the pipeline impact to the environment. The Geo-Environmental mapping was built to stress the influence of soil/structure interaction, related to the physical effect that comes from the contact between structures and soil or rock. A Geological-Geotechnical-Environmental strip (chart) was presented to emphasize the pipeline operational constrains and its influence to the environment. The mapping was developed to clearly show the occurrence and properties of geological materials divided into geotechnical domain units (zones). The strips present construction natural properties, such as: excavability, stability of the excavation and soil re-use capability. Also, the environmental constrains were added to the geological-geotechnical mapping. The Geo-Environmental Mapping model helps the planning of the geotechnical and environmental inquiries to be carried out during executive design, the discussion on the types of equipment to be employed during construction and the analysis of the geological risks and environmental impacts to be faced during the built of the pipeline. (author)

  2. Message Design for Mobile Learning: Learning Theories, Human Cognition and Design Principles

    Science.gov (United States)

    Wang, Minjuan; Shen, Ruimin

    2012-01-01

    The demands of an increasingly knowledge-based society and the dramatic advances in mobile phone technology are combining to spur the growth of mobile learning (mLearning). However, for mLearning to attain its full potential, it is essential to develop pedagogy and instructional design tailored to the needs of this new learning environment. At…

  3. Principles of loads and failure mechanisms applications in maintenance, reliability and design

    CERN Document Server

    Tinga, T

    2013-01-01

    Failure of components or systems must be prevented by both designers and operators of systems, but knowledge of the underlying mechanisms is often lacking. Since the relation between the expected usage of a system and its failure behavior is unknown, unexpected failures often occur, with possibly serious financial and safety consequences. Principles of Loads and Failure Mechanisms.  Applications in Maintenance, Reliability and Design provides a complete overview of all relevant failure mechanisms, ranging from mechanical failures like fatigue and creep to corrosion and electric failures. Both qualitative and quantitative descriptions of the mechanisms and their governing loads enable a solid assessment of a system’s reliability in a given or assumed operational context. Moreover, a unique range of applications of this knowledge in the fields of maintenance, reliability and design are presented. The benefits of understanding the physics of failure are demonstrated for subjects like condition monitoring, pre...

  4. Design principles and fundamental trade-offs in biomimetic light harvesting

    CERN Document Server

    Sarovar, Mohan

    2012-01-01

    Recent developments in synthetic and supramolecular chemistry have created opportunities to design organic systems with tailored nanoscale structure for various technological applications. A key application area is the capture of light energy and its conversion into electrochemical or chemical forms for photovoltaic or sensing applications. In this work we consider cylindrical assemblies of chromophores that model structures produced by several supramolecular techniques. Our study is especially guided by the versatile structures produced by virus-templated assembly. We use a multi-objective optimization framework to determine design principles and limitations in light harvesting performance for such assemblies, both in the presence and absence of disorder. We identify a fundamental trade-off in cylindrical assemblies that is encountered when attempting to maximize both efficiency of energy transfer and absorption bandwidth. We also rationalize the optimal design strategies and provide explanations for why var...

  5. Applying conceptual design to B2B sales negotiations

    DEFF Research Database (Denmark)

    Illi, Mikko; Ylirisku, Salu

    This paper addresses the challenge of perceiving B2B sales negotiation in a manner that would open up new possibilities for the improvement of the practice. B2B sales agents work under high pressure in developing relevant and appealing proposals when negotiating for a deal with a customer. The key...... problem that will be addressed is the building of understanding of a customer’s current needs and requirements, and then trying to devise an appropriate proposal to match these. The work of the sales agents in B2B sales negotiations is highly complex, as they need to understand both the modular machinery...... the ways in which design sense making artefacts may drive also B2B sales agents’ work....

  6. Applying Quality by Design Concepts to Pharmacy Compounding.

    Science.gov (United States)

    Timko, Robert J

    2015-01-01

    Compounding of medications is an important part of the practice of the pharmacy profession. Because compounded medications do not have U.S. Food and Drug Administration approval, a pharmacist has the responsibility to ensure that compounded medications are of suitable quality, safety, and efficacy. The Federal Government and numerous states have updated their laws and regulations regarding pharmacy compounding as a result of recent quality issues. Compounding pharmacists are expected to follow good preparation prodecures in their compounding practices in much the same way pharmaceutical manufacturers are required to follow Current Good Manufacturing Procedures as detailed in the United States Code of Federal Regulations. Application of Quality by Design concepts to the preparation process for a compounded medication can help in understanding the potential pitfalls and the means to mitigate their impact. The goal is to build quality into the compounding process to ensure that the resultant compounded prescription meets the human or animal patients' requirements. PMID:26891559

  7. DiCoT: A methodology for applying Distributed Cognition to the design of teamworking systems

    OpenAIRE

    Blandford, A.; Furniss, D.

    2006-01-01

    Distributed Cognition is growing in popularity as a way of reasoning about group working and the design of artefacts within work systems. DiCoT (Distributed Cognition for Teamwork) is a methodology and representational system we are developing to support distributed cognition analysis of small team working. It draws on ideas from Contextual Design, but re-orients them towards the principles that are central to Distributed Cognition. When used to reason about possible changes to the design of ...

  8. PRINCIPLES OF DESIGNING THE CENTER FOR ADMINISTRATIVE SERVICES IN DNIPROPETROVS’K

    Directory of Open Access Journals (Sweden)

    PODOLYNNY S. I.

    2016-01-01

    Full Text Available Problem. Nowadays providing administrative services of good quality is considered to be one of the most important conditions for establishing firm and democratic relations between local authorities and population The work for creating municipal institutions using the principle of a "single window" is being fulfilled in Dnipropetrovs’k. Two pilot projects have been done at the Department of Architectural Engineering and Design (Prydniprovs’ka State Academy of Construction and Architecture. Objective. To demonstrate peculiarities of two project proposals for CAS comparing them with the recommendations of State Administration and basic principles formed while designing similar objects in foreign practice. Main part. Basic principles for creating the Center for Administrative Services (CAS were formulated regarding foreign experience and recommendations of State Administration. These principles are organized as three conceptual blocks: city-planning relevancy, functional arrangement, form making and artistic image peculiarities. CAS on the left bank of the river is situated on the territory that is being reconstructed at the moment. It is a functional and compositional landmark of social and administrative subcentre of the left bank. The Centre is designed in a 16-storey building with a build-in and build-on 2-floor block of the front-office. The front-office is designed for 121 working places and the back-office – for 440 ones. The general area of the front-office is 605 sq. m., the area of the back-office is 2130 sq. m. Artistic characteristics are designed according to traditional office planning schemes. CAS of the right bank is planned on a vacant site on Zaporiz’ke highway. Spacious parking lots are also provided on the territory. The building is positioned sideways on to the highway with its long axis. It can serve as a peculiar sign at the entrance to the city. The front-office is situated in a two-floor stylobate of the Center

  9. Integration of Instructional Design Principles to Online Courses and Faculty Training in Three Puerto Rican Institutions of Higher Education

    Science.gov (United States)

    Perez, Wanda W.

    2011-01-01

    Research on how the principles of instructional design are taught in faculty training courses for online teaching and how faculty members incorporate these principles into their online courses is limited. This gap in the research literature is especially pronounced when considering the relatively new online learning context of Puerto Rico's higher…

  10. Innovative Design of a Rigid Package Container Applied in Ultra High Pressure Food Processing Based on TRIZ

    Directory of Open Access Journals (Sweden)

    Rong-Li Li

    2013-07-01

    Full Text Available An innovative structure of Rigid Package Container (RPC was designed based on TRIZ for improving productivity. The technical contradiction of RPC was solved by TRIZ contradiction analysis methodologies and obtained solution principles. Then mechanical analysis on sealing process of o-rings and structural optimization on its key components of RPC were completed. Ultimately, optimized structures of RPC had been achieved. Experiments on the sealing properties had stated that this structure was reasonable and reliable in sealing, easy to assembly and disassembly, compact structure and light weight. Thus, this innovative RPC could be applied in many ultra high pressure vessels in food industry.

  11. The hybrid K-edge/K-XRF densitometer: Principles - design - performance

    International Nuclear Information System (INIS)

    The Euratom Safeguards Directorate (ESD) has recently installed a hybrid K-edge/K-XRF densitometer in a commerical reprocessing plant for the safeguarding of nuclear materials. This instrument, developed at KfK Karlsruhe, offers for the first time analytical measurement capabilities for timely on-site input accountancy verification. Lectures providing informations on measurement principles, instrument design features and performance data have been given to inspectors of ESD to make them familiar with the new instrument. This report summarizes the essential materials presented during these courses. (orig.)

  12. AmI in good care? Developing design principles for ambient intelligent domotics for elderly.

    Science.gov (United States)

    Meulendijk, Michiel; Van De Wijngaert, Lidwien; Brinkkemper, Sjaak; Leenstra, Herbert

    2011-03-01

    The combination of ambient intelligence (AmI) and domotics has the potential to respond to elderly people's desire to live independent from extensive forms of care. Their slow adoption of technological aids shows reluctance, though. This article investigates their motivations to adopt ambient intelligent domotics, and proposes design principles specifically based on their preferences and experiences. Respondents appeared to be more acceptive of tangible problems they expected with AmI domotics than intangible ones. In addition, their opinions seemed to be profoundly influenced by the way they perceived their psychological quality of life, while their physical conditions did not seem to have noticeable impacts. PMID:21291298

  13. From First Principles Design to Realization of Bimetallic Catalysts for Enhanced Selectivity

    Energy Technology Data Exchange (ETDEWEB)

    Lobo, Raul F.; Crooks, Richard M.; Mavrikakis, Manos

    2014-04-08

    “Catalysis by design” has been a dream for decades. To specify the composition and structure of matter to effect a desired catalytic transformation with desired and predicted rate and selectivity remains a monumental challenge, especially in heterogeneous catalysis. Our research thrusts have been chosen not only for their practical and scientific relevance, e.g. for more efficient and sustainable chemicals and fuels production, but also because they provide a foundation for developing and exploring broadly applicable principles and strategies for catalyst design.

  14. The PBIL algorithm applied to a nuclear reactor design optimization

    International Nuclear Information System (INIS)

    The Population-Based Incremental Learning (PBIL) algorithm is a method that combines the mechanism of genetic algorithm with the simple competitive learning, creating an important tool to be used in the optimization of numeric functions and combinatory problems. PBIL works with a set of solutions to the problems, called population, whose objective is create a probability vector, containing real values in each position, that when used in a decoding procedure gives subjects that present the best solutions for the function to be optimized. In this work a new form of learning for algorithm PBIL is developed, having aimed at to reduce the necessary time for the optimization process. This new algorithm will be used in the nuclear reactor design optimization. The optimization problem consists in adjusting several reactor cell parameters, such as dimensions, enrichment and materials, in order to minimize the average peak-factor in a 3-enrichment zone reactor, considering some restrictions. In this optimization is used the computational code HAMMER, and the results compared with other methods of optimization by artificial intelligence. (author)

  15. Applied design methodology for lunar rover elastic wheel

    Science.gov (United States)

    Cardile, Diego; Viola, Nicole; Chiesa, Sergio; Rougier, Alessandro

    2012-12-01

    In recent years an increasing interest in the Moon surface operations has been experienced. In the future robotic and manned missions of Moon surface exploration will be fundamental in order to lay the groundwork for more ambitious space exploration programs. Surface mobility systems will be the key elements to ensure an efficient and safe Moon exploration. Future lunar rovers are likely to be heavier and able to travel longer distances than the previously developed Moon rover systems. The Lunar Roving Vehicle (LRV) is the only manned rover, which has so far been launched and used on the Moon surface. Its mobility system included flexible wheels that cannot be scaled to the heavier and longer range vehicles. Thus the previously developed wheels are likely not to be suitable for the new larger vehicles. Taking all these considerations into account, on the basis of the system requirements and assumptions, several wheel concepts have been discussed and evaluated through a trade-off analysis. Semi-empirical equations have been utilized to predict the wheel geometrical characteristics, as well as to estimate the motion resistances and the ability of the system to generate thrust. A numerical model has also been implemented, in order to define more into the details the whole wheel design, in terms of wheel geometry and physical properties. As a result of the trade-off analysis, the ellipse wheel concept has shown the best behavior in terms of stiffness, mass budget and dynamic performance. The results presented in the paper have been obtained in cooperation with Thales Alenia Space-Italy and Sicme motori, in the framework of a regional program called STEPS . STEPS-Sistemi e Tecnologie per l'EsPlorazione Spaziale is a research project co-financed by Piedmont Region and firms and universities of the Piedmont Aerospace District in the ambit of the P.O.R-F.E.S.R. 2007-2013 program.

  16. Chemical Frustration. A Design Principle for the Discovery of New Complex Alloy and Intermetallic Phases, Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Fredrickson, Daniel C [Univ. of Wisconsin, Madison, WI (United States)

    2015-06-23

    Final technical report for "Chemical Frustration: A Design Principle for the Discovery of New Complex Alloy and Intermetallic Phases" funded by the Office of Science through the Materials Chemistry Program of the Office of Basic Energy Sciences.

  17. Environmental risk and the precautionary principle. “Late lessons from early warnings” applied to genetically modified plants

    OpenAIRE

    Aslaksen, Iulie; Natvig, Bent; Nordal, Inger

    2004-01-01

    Abstract: The environmental risk associated with genetically modified organisms (GMO) implies that new approaches to risk assessment, risk management and risk communication are needed. In this paper we discuss the role of the precautionary principle in policy responses to GMO risk. We first discuss application of the criteria in the European Environment Agency report “Late lessons from early warnings: The precautionary principle 1896-2000” to environmental GMO risk, with focus ...

  18. Applications of electromagnetic principles in the design and development of proximity wireless sensors

    Science.gov (United States)

    Alam, Md Nazmul

    Sensors and sensing system are playing dominant roles in monitoring the health of infrastructure, such as bridges, power lines, gas pipelines, rail roads etc. Sensing modalities employing Surface Acoustic Waves (SAW), Electromagnetic (EM) and optical have been investigated and reported. Sensors that utilize the perturbation of EM fields as function of the change in the physical structural or material phenomenon are of particular interest because of their inherent synergy with electronic system and diagnostic techniques, e.g. Time Domain Reflectometry (TDR), Joint-Time-Frequency-Domain-Reflectometry (JTFDR). The focus of this work is to study and develop new sensing and monitoring concepts that are based on EM principles. First, the analyses, design and development of a static electric field type sensor are presented for application in embedded concrete moisture content measurement. The analytical formulation and results based on conformal mapping method for an interdigitated sensor clearly show the dependency of the field penetration depth and the inter-electrode capacitance on the electrode sizes and their spacings. It is observed that larger electrode size and small separation are needed in order to achieve substantially higher capacitance or large field penetration depth. A meander and a circular sensor are fabricated and tested to demonstrate concrete moisture content measurements that show that moisture content is a linear function of sensor interelectrode capacitance. Second, sub-wavelength dimension non-intrusive wave launchers are designed and tested that can launch TDR or JTFDR type broadband surface wave waveforms in the VHF-UHF bands in order to detect cable faults. Greater than 3:1 transmission bandwidth (100-300 MHz) is obtained with a cylindrical launcher on square orthogonal ground plane while with a CSW launcher more than an octave (100-240 MHz) bandwidth is achieved. Open circuit faults are detected using surface waves and TDR on two XLPE cables

  19. Design principles for high efficiency small-grain polysilicon solar cells, with supporting experimental studies

    Science.gov (United States)

    Lindholm, F. A.; Neugroschel, A.; Sah, C. T.

    1982-01-01

    Design principles suggested here aim toward high conversion efficiency (greater than 15 percent) in polysilicon cells. The principles seek to decrease the liabilities of both intragranular and grain-boundary-surface defects. The advantages of a phosphorus atom concentration gradient in a thin (less than 50 microns) base of a p(+)/n(x)/n(+) drift-field solar cell, which produces favorable gradients in chemical potential, minority-carrier mobility and diffusivity, and recombination lifetime (via phosphorus gettering) are suggested. The degrading effects of grain boundaries are reduced by these three gradients and by substituting atoms (P, H, F or Li) for vacancies on the grain-boundary surface. From recent experiments comes support for the benefits of P diffusion down grain boundaries and, for quasi-grain-boundary-free and related structures. New analytic solutions for the n(x)-base include the effect of a power-law dependence between P concentration and lifetime. These provide an upper-bound estimate on the open circuit voltage. Finite-difference numerical solutions of the six Shockley equations furnish complete information about all solar-cell parameters and add insight concerning design.

  20. Design principle for absorption enhancement with nanoparticles in thin-film silicon solar cells

    International Nuclear Information System (INIS)

    The use of nanoparticles in solar cells has created many controversies. In this paper, different mechanisms of nanoparticles with different materials with diameters varying from 50 to 200 nm, surface coverage at 5, 20, and 60 %, and different locations are analyzed systematically for efficient light trapping in a thin-film c-Si solar cell. Mie theory and the finite difference time domain method are used for analysis to give a design principle with nanoparticles for the solar cell application. Metals exhibit plasmonic resonances and angular scattering, while dielectrics show anti-reflection and scattering in the incident direction. A table is given to summarize the advantages and disadvantages in different conditions. The silicon absorption enhancement with nanoparticles on top is mainly in the shorter wavelengths below 700 nm, and both Al and SiO2 nanoparticles with diameter around 100 nm show the most significant enhancement. The silicon absorption enhancement with embedded nanoparticles takes place in the longer wavelengths over 700 nm, and Ag and SiO2 nanoparticles with larger diameter around 200 nm perform better. However, the light absorbed by Ag nanoparticles will be converted to heat and will lead to decrease in cell efficiency; hence, the choice of metallic nanoparticles in applications to solar cells should be carefully considered. The design principle proposed in this work gives a guideline by choosing reasonable parameters for the different requirements in the application of thin-film solar cells

  1. A biosensor based on graphene nanoribbon with nanopores: a first-principles devices-design

    Institute of Scientific and Technical Information of China (English)

    Ouyang Fang-Ping; Peng Sheng-Lin; Zhang Hua; Weng Li-Bo; Xu Hui

    2011-01-01

    A biosensor device, built from graphene nanoribbons (GNRs) with nanopores, was designed and studied by firstprinciples quantum transport simulation. We have demonstrated the intrinsic transport properties of the device and the effect of different nucleobases on device properties when they are located in the nanopores of GNRs. It was found that the device's current changes remarkably with the species of nucleobases, which originates from their different chemical compositions and coupling strengths with GNRs. In addition, our first-principles results clearly reveal that the distinguished ability of a device's current depends on the position of the pore to some extent. These results may present a new way to read off the nucleobases sequence of a single-stranded DNA (ssDNA) molecule by such GNRs-based device with designed nanopores

  2. The risk-escalation model: a principled design strategy for early-phase trials.

    Science.gov (United States)

    Hey, Spencer Phillips; Kimmelman, Jonathan

    2014-06-01

    Should first-in-human trials be designed to maximize the prospect of therapeutic benefit for volunteers, prioritize avoidance of unintended harms, or aim for some happy medium between the two? Perennial controversies surrounding initiation and design of early-phase trials hinge on how this question is resolved. In this paper, we build on the premise that the task of early-phase testing is to optimize various components of a potential therapy so that later, confirmatory trials have the maximal probability of informing drug development and clinical care. We then explore three strategies that investigators might use to manage trial risks while optimizing a therapy, using cell therapy for Amyotrophic Lateral Sclerosis (ALS) as an example. We argue that an iterative application of maximin strategies over successive cohorts and trials, which we call the "risk-escalation model," establishes a moral principle that should guide decision-making in early-phase trials. PMID:25109092

  3. Design principles for CANDU control centres in response to evolving utility business needs

    International Nuclear Information System (INIS)

    Nuclear generation operators are facing a challenging business environment at the beginning of the new millennium. Evolving changes in business context, competitive commercial pressures, and changes in technology have dictated recurring evaluation of operational practices and the adequacy of supporting tools, and the pursuit of opportunities for operational improvement. A key area of utility operations that has been impacted by these changes is the nuclear plant control centre. Changes to workspace layout, equipment provisions, staffing, and work organization are examples of some of the adjustments being introduced to improve operational and safety effectiveness. This paper discusses some of the key factors influencing these changes and identifies additional design principles for CANDU control centres that will enable new control centre designs and retrofits of existing control centres to remain relevant and responsive to utility needs. (author)

  4. Applying Software Engineering Methodology for Designing Biomedical Software Devoted To Electronic Instrumentation

    Directory of Open Access Journals (Sweden)

    Alderico Rodrigues de Paula Junior

    2012-01-01

    Full Text Available Problem statement: Significant effort goes into the development of biomedical software, which is integrated with computers/processors, sensors and electronic instrumentation devoted to a specific application. However, the scientific work on electronic instrumentation controlled by biomedical software has not emphasized software development, instead focusing mainly on electronics engineering. The development team is rarely composed of Software Engineering (SE experts. Usually, a commercial automated tools environment is not used due to its high cost and complexity for researchers from other areas to understand. Approach: This present study reports how the SE approach was applied to design and develop biomedical software, which is part of a Computerized Electronic Instrumentation (CEI. This CEI comprises software and an electronic instrumentation based on a force sensor and electrogoniometer to monitor the hand exertion of computer user during typing task. The aim is to serve as a guideline for academic researchers who are not expert in software engineering methodology but usually develop their own software to run with their CEI. The specification of the requirements, presented as use case, includes the context diagram, the data flow diagram, the entity relationship diagram and test procedure. The Unified Modelling Language from the Enterprise Architect tool was used. The developed software and the electronic instrumentation were tested together. Results: A sample of the interface screen shows how the outcomes could be plotted in an integrated manner. By comparing the values with other values obtained by manual calculations and with those provided by sensor manufacturer, the repeatability of test procedure validated the results. Reliable electronic instrumentation when working with unreliable software can become unreliable. Conclusion: Applying software engineering methodology principles provided a simple and clear documentation that was helpful

  5. Applying Universal Instructional Design to Course Websites by Using Course Evaluations

    Science.gov (United States)

    Carter, Irene; Leslie, Donald; Kwan, Denise

    2012-01-01

    The authors explore their use of learner-centred teaching strategies and Universal Instructional Design (UID) on course websites. UID is based on universal design, the design of products and environments intended to be usable by all people to the greatest extent possible (Burgstahler & Cory, 2008). UID applies universal design to instructional…

  6. Design principles and fundamental trade-offs in biomimetic light harvesting

    International Nuclear Information System (INIS)

    Recent developments in synthetic and supramolecular chemistry have created opportunities to design organic systems with tailored nanoscale structure for various technological applications. A key application area is the capture of light energy and its conversion into electrochemical or chemical forms for photovoltaic or sensing applications. In this work we consider cylindrical assemblies of chromophores that model structures produced by several supramolecular techniques. Our study is especially guided by the versatile structures produced by virus-templated assembly. We use a multi-objective optimization framework to determine design principles and limitations in light harvesting performance for such assemblies, both in the presence and absence of disorder. We identify a fundamental trade-off in cylindrical assemblies that is encountered when attempting to maximize both efficiency of energy transfer and absorption bandwidth. We also rationalize the optimal design strategies and provide explanations for why various structures provide optimal performance. Most importantly, we find that the optimal design strategies depend on the amount of energetic and structural disorder in the system. The aim of these studies is to develop a program of quantum-informed rational design for construction of organic assemblies that have the same degree of tailored nanoscale structure as biological photosynthetic light harvesting complexes, and consequently have the potential to reproduce their remarkable light harvesting performance. (paper)

  7. Biomaterial based modulation of macrophage polarization: a review and suggested design principles

    Directory of Open Access Journals (Sweden)

    Rukmani Sridharan

    2015-07-01

    Full Text Available Macrophages have long been known for their phagocytic capabilities and immune defence; however, their role in healing is being increasingly recognized in recent years due to their ability to polarize into pro-inflammatory and anti-inflammatory phenotypes. Historically, biomaterials were designed to be inert to minimize the host response. More recently, the emergence of tissue engineering and regenerative medicine has led to the design of biomaterials that interact with the host through tailored mechanical, chemical and temporal characteristics. Due to such advances in biomaterial functionality and an improved understanding of macrophage responses to implanted materials, it is now possible to identify biomaterial design characteristics that dictate the host response and contribute to successful tissue integration. Herein, we begin by briefly reviewing macrophage cell origin and the key cytokine/chemokine markers of macrophage polarization and then describe which responses are favorable for both replacement and regenerative biomaterials. The body of the review focuses on macrophage polarization in response to inherent cues directly provided by biomaterials and the consequent cues that result from events related to biomaterial implantation. To conclude, a section on potential design principles for both replacement and regenerative biomaterials is presented. An in depth understanding of biomaterial cues to selectively polarize macrophages may prove beneficial in the design of a new generation of ‘immuno-informed’ biomaterials that can positively interact with the immune system to dictate a favorable macrophage response following implantation.

  8. Impact of first-principles properties of deuterium–tritium on inertial confinement fusion target designs

    International Nuclear Information System (INIS)

    A comprehensive knowledge of the properties of high-energy-density plasmas is crucial to understanding and designing low-adiabat, inertial confinement fusion (ICF) implosions through hydrodynamic simulations. Warm-dense-matter (WDM) conditions are routinely accessed by low-adiabat ICF implosions, in which strong coupling and electron degeneracy often play an important role in determining the properties of warm dense plasmas. The WDM properties of deuterium–tritium (DT) mixtures and ablator materials, such as the equation of state, thermal conductivity, opacity, and stopping power, were usually estimated by models in hydro-codes used for ICF simulations. In these models, many-body and quantum effects were only approximately taken into account in the WMD regime. Moreover, the self-consistency among these models was often missing. To examine the accuracy of these models, we have systematically calculated the static, transport, and optical properties of warm dense DT plasmas, using first-principles (FP) methods over a wide range of densities and temperatures that cover the ICF “path” to ignition. These FP methods include the path-integral Monte Carlo (PIMC) and quantum-molecular dynamics (QMD) simulations, which treat electrons with many-body quantum theory. The first-principles equation-of-state table, thermal conductivities (κQMD), and first principles opacity table of DT have been self-consistently derived from the combined PIMC and QMD calculations. They have been compared with the typical models, and their effects to ICF simulations have been separately examined in previous publications. In this paper, we focus on their combined effects to ICF implosions through hydro-simulations using these FP-based properties of DT in comparison with the usual model simulations. We found that the predictions of ICF neutron yield could change by up to a factor of ∼2.5; the lower the adiabat of DT capsules, the more variations in hydro-simulations. The FP-based properties

  9. Impact of first-principles properties of deuterium–tritium on inertial confinement fusion target designs

    Energy Technology Data Exchange (ETDEWEB)

    Hu, S. X., E-mail: shu@lle.rochester.edu; Goncharov, V. N.; Boehly, T. R.; McCrory, R. L.; Skupsky, S. [Laboratory for Laser Energetics, University of Rochester, 250 East River Road, Rochester, New York 14623-1299 (United States); Collins, L. A.; Kress, J. D. [Theoretical Division, Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States); Militzer, B. [Department of Earth and Planetary Science and Department of Astronomy, University of California, Berkeley, California 94720 (United States)

    2015-05-15

    A comprehensive knowledge of the properties of high-energy-density plasmas is crucial to understanding and designing low-adiabat, inertial confinement fusion (ICF) implosions through hydrodynamic simulations. Warm-dense-matter (WDM) conditions are routinely accessed by low-adiabat ICF implosions, in which strong coupling and electron degeneracy often play an important role in determining the properties of warm dense plasmas. The WDM properties of deuterium–tritium (DT) mixtures and ablator materials, such as the equation of state, thermal conductivity, opacity, and stopping power, were usually estimated by models in hydro-codes used for ICF simulations. In these models, many-body and quantum effects were only approximately taken into account in the WMD regime. Moreover, the self-consistency among these models was often missing. To examine the accuracy of these models, we have systematically calculated the static, transport, and optical properties of warm dense DT plasmas, using first-principles (FP) methods over a wide range of densities and temperatures that cover the ICF “path” to ignition. These FP methods include the path-integral Monte Carlo (PIMC) and quantum-molecular dynamics (QMD) simulations, which treat electrons with many-body quantum theory. The first-principles equation-of-state table, thermal conductivities (κ{sub QMD}), and first principles opacity table of DT have been self-consistently derived from the combined PIMC and QMD calculations. They have been compared with the typical models, and their effects to ICF simulations have been separately examined in previous publications. In this paper, we focus on their combined effects to ICF implosions through hydro-simulations using these FP-based properties of DT in comparison with the usual model simulations. We found that the predictions of ICF neutron yield could change by up to a factor of ∼2.5; the lower the adiabat of DT capsules, the more variations in hydro-simulations. The FP

  10. The Spatial Vision Tree: A Generic Pattern Recognition Engine- Scientific Foundations, Design Principles, and Preliminary Tree Design

    Science.gov (United States)

    Rahman, Zia-ur; Jobson, Daniel J.; Woodell, Glenn A.

    2010-01-01

    New foundational ideas are used to define a novel approach to generic visual pattern recognition. These ideas proceed from the starting point of the intrinsic equivalence of noise reduction and pattern recognition when noise reduction is taken to its theoretical limit of explicit matched filtering. This led us to think of the logical extension of sparse coding using basis function transforms for both de-noising and pattern recognition to the full pattern specificity of a lexicon of matched filter pattern templates. A key hypothesis is that such a lexicon can be constructed and is, in fact, a generic visual alphabet of spatial vision. Hence it provides a tractable solution for the design of a generic pattern recognition engine. Here we present the key scientific ideas, the basic design principles which emerge from these ideas, and a preliminary design of the Spatial Vision Tree (SVT). The latter is based upon a cryptographic approach whereby we measure a large aggregate estimate of the frequency of occurrence (FOO) for each pattern. These distributions are employed together with Hamming distance criteria to design a two-tier tree. Then using information theory, these same FOO distributions are used to define a precise method for pattern representation. Finally the experimental performance of the preliminary SVT on computer generated test images and complex natural images is assessed.

  11. The spatial vision tree: a generic pattern recognition engine: scientific foundations, design principles, and preliminary tree design

    Science.gov (United States)

    Rahman, Zia-ur; Jobson, Daniel J.; Woodell, Glenn A.

    2010-04-01

    New foundational ideas are used to define a novel approach to generic visual pattern recognition. These ideas proceed from the starting point of the intrinsic equivalence of noise reduction and pattern recognition when noise reduction is taken to its theoretical limit of explicit matched filtering. This led us to think of the logical extension of sparse coding using basis function transforms for both de-noising and pattern recognition to the full pattern specificity of a lexicon of matched filter pattern templates. A key hypothesis is that such a lexicon can be constructed and is, in fact, a generic visual alphabet of spatial vision. Hence it provides a tractable solution for the design of a generic pattern recognition engine. Here we present the key scientific ideas, the basic design principles which emerge from these ideas, and a preliminary design of the Spatial Vision Tree (SVT). The latter is based upon a cryptographic approach whereby we measure a large aggregate estimate of the frequency of occurrence (FOO) for each pattern. These distributions are employed together with Hamming distance criteria to design a two-tier tree. Then using information theory, these same FOO distributions are used to define a precise method for pattern representation. Finally the experimental performance of the preliminary SVT on computer generated test images and complex natural images is assessed.

  12. A New Approach in Design and Operating Principle of Silicone Tactile Sensor

    Directory of Open Access Journals (Sweden)

    Bakri Ali

    2010-01-01

    Full Text Available Problem statement: Research and development in tactile sensor are escalating due to the fact that advanced robot needs to interact with surrounding environments which is very complex, dynamic, uncontrolled and difficult to perceive reliably. Recent research has been focusing in development of new tactile sensor that takes advantage of advances in materials, Micro-Electromechanical Systems (MEMS and semiconductor technology. To date, several basic sensing principles are commonly used in tactile sensor such as capacitive sensor, piezoelectric sensor, inductive sensor, opto-electrical and piezo-resistive sensor. However they are still lack of sensitivity and low dynamic range in sensing the changes of forces in 3 axes and not durable enough to perform in various working environments. Approach: Three different designs of optical tactile sensor was proposed and analyzed. The overall design of the test-rig of the system was presented. The working principle was based on the deformation of the silicone tactile sensor. The deformation image will be transferred through high quality medical fiberscope and will be recorded using a CCD camera. The image will be stored in a computer for further analysis to relate the image with the given forces. These data can be used to control a robotic gripper so that it can perform gently and precisely like human tactile sensing capability but with greater strength and durability in various working environments. Results: The sensor had been designed and an experimental test rig was developed. Initial experiment was carried out to check the potential of this technique. Based on results, there is almost a linear relationship between the forces and the deformation of the tactile sensor. The amount of deformation is calculated based on the analyzed image data. Conclusion: The results of the experiment gave a convincing idea and provide a ground for further research to enhance this system to be an alternative tactile sensor in

  13. USING OF OBJECT-ORIENTED DESIGN PRINCIPLES IN ELECTRIC MACHINES DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    N.N. Zablodskii

    2016-03-01

    Full Text Available Purpose. To develop the theoretical basis of electrical machines object-oriented design, mathematical models and software to improve their design synthesis, analysis and optimization. Methodology. We have applied object-oriented design theory in electric machines optimal design and mathematical modelling of electromagnetic transients and electromagnetic field distribution. We have correlated the simulated results with the experimental data obtained by means of the double-stator screw dryer with an external solid rotor, brushless turbo-generator exciter and induction motor with squirrel cage rotor. Results. We have developed object-oriented design methodology, transient mathematical modelling and electromagnetic field equations templates for cylindrical electrical machines, improved and remade Cartesian product and genetic optimization algorithms. This allows to develop electrical machines classifications models, included not only structure development but also parallel synthesis of mathematical models and design software, to improve electric machines efficiency and technical performance. Originality. For the first time, we have applied a new way of design and modelling of electrical machines, which is based on the basic concepts of the object-oriented analysis. For the first time is suggested to use a single class template for structural and system organization of electrical machines, invariant to their specific variety. Practical value. We have manufactured screw dryer for coil dust drying and mixing based on the performed object-oriented theory. We have developed object-oriented software for design and optimization of induction motor with squirrel cage rotor of AIR series and brushless turbo-generator exciter. The experimental studies have confirmed the adequacy of the developed object-oriented design methodology.

  14. The principles and guidelines for designing long-term agronomic experiments

    Institute of Scientific and Technical Information of China (English)

    Mark; Conyers

    2009-01-01

    Many of the important questions facing farming systems in the world today require long-term studies to provide meaningful information and answers. A long-term agronomic experiment (LTAE) should (1) have long-term objectives; (2) study important soil processes or ecological processes; and (3) be related to the productivity and sustainability of systems. A well established LTAE can provide both insights into how the system operates and foresight into where the system goes. The prerequisites for setting up a LTAE are the secured land, continuous funding and dedicated scientists. A number of principles must be considered carefully when establishing a LTAE, (1) the site must be representative of large areas; (2) the treatments should be simple, but focusing on the big questions; (3) the plots should be large enough to allow subsequent modification of the experiment if this becomes necessary; (4) crop rotations should minimise, wherever possible, the risk of build-up of pests and diseases, and rotational phase should be considered in a rotational experiment; (5) a clearly defined experimental protocol should be developed to ensure data collected is scientifically valid and statistically analysable, but with flexibility to allow essential changes; (6) soil samples, possibly plant samples, should be achieved to provide better answer to the original questions when new, perhaps more accurate analytical techniques are developed, or answer new research questions that were not considered in the original design. The MASTER experiment in Australia was used as a case study to demonstrate how these principles are implemented in practice.

  15. Design principle of TVO's final repository and preliminary adaptation to site specific conditions

    International Nuclear Information System (INIS)

    Teollisuuden Voima Oy (TVO) is responsible for the management of spent fuel produced by the Olkiluoto power plant. TVO's current programme of spent fuel management is based on the guidelines and time schedule set by the Finnish Government. TVO has studied a final disposal concept in which the spent fuel bundles are encapsulated in copper canisters and emplaced in Finnish bedrock. According to the plan the final repository for spent fuel will be in operation by 2020. TVO's updated technical plans for the disposal of spent fuel together with a performance analysis (TVO-92) were submitted to the authorities in 1992. The paper describes the design principle of TVO's final repository and preliminary adaptation of the repository to site specific conditions. (author). 10 refs., 5 figs

  16. Rational design of Nb-based alloys for hydrogen separation: A first principles study

    Directory of Open Access Journals (Sweden)

    Byungki Ryu

    2013-02-01

    Full Text Available We have investigated the effect of alloying metal elements on hydrogen solubility and mechanical integrity of Nb-based alloys, Nb15M1 (where M = Ca–Zn, Ge, using first principles-based calculations. In general, the chemical interaction between the interstitial H and metal is weakened as the alloying element is changed from an early to a late transition metal, leading to lower H solubility and higher resistance to H embrittlement. This effect becomes more pronounced when a smaller alloying element is used due to stronger elastic interaction between interstitial H and metal atoms. These finding may provide scientific basis for rational design of Nb-based hydrogen separation membranes with tailored H solubility to effectively suppress H embrittlement while maintaining excellent hydrogen permeation rate.

  17. Novel Geometrical Concept of a High Performance Brain PET Scanner Principle, Design and Performance Estimates

    CERN Document Server

    Séguinot, Jacques; Chesi, Enrico Guido; Joram, C; Mathot, S; Weilhammer, P; Chamizo-Llatas, M; Correia, J G; Ribeiro da Silva, M; Garibaldi, F; De Leo, R; Nappi, E; Corsi, F; Dragone, A; Schoenahl, F; Zaidi, H

    2006-01-01

    We present the principle, a possible implementation and performance estimates of a novel geometrical concept for a high resolution positron emission tomograph. The concept, which can for example be implemented in a brain PET device, promisses to lead to an essentially parallax free 3D image reconstruction with excellent spatial resolution and constrast, uniform over the complete field of view. The key components are matrices of long axially oriented scintillator crystals which are read out at both extremities by segmented Hybrid Photon Detectors. We discuss the relevant design considerations for a 3D axial PET camera module, motivate parameter and material choices, and estimate its performance in terms of spatial and energy resolution. We support these estimates by Monte Carlo simulations and in some cases by first experimental results. From the performance of a camera module, we extrapolate to the reconstruction resolution of a 3D axial PET scanner in a semi-analytical way and compare it to an existing state...

  18. Design of a speed meter interferometer proof-of-principle experiment

    Science.gov (United States)

    Gräf, C.; Barr, B. W.; Bell, A. S.; Campbell, F.; Cumming, A. V.; Danilishin, S. L.; Gordon, N. A.; Hammond, G. D.; Hennig, J.; Houston, E. A.; Huttner, S. H.; Jones, R. A.; Leavey, S. S.; Lück, H.; Macarthur, J.; Marwick, M.; Rigby, S.; Schilling, R.; Sorazu, B.; Spencer, A.; Steinlechner, S.; Strain, K. A.; Hild, S.

    2014-11-01

    The second generation of large scale interferometric gravitational wave (GW) detectors will be limited by quantum noise over a wide frequency range in their detection band. Further sensitivity improvements for future upgrades or new detectors beyond the second generation motivate the development of measurement schemes to mitigate the impact of quantum noise in these instruments. Two strands of development are being pursued to reach this goal, focusing both on modifications of the well-established Michelson detector configuration and development of different detector topologies. In this paper, we present the design of the world's first Sagnac speed meter (SSM) interferometer, which is currently being constructed at the University of Glasgow. With this proof-of-principle experiment we aim to demonstrate the theoretically predicted lower quantum noise in a Sagnac interferometer compared to an equivalent Michelson interferometer, to qualify SSM for further research towards an implementation in a future generation large scale GW detector, such as the planned Einstein telescope observatory.

  19. Design of a speed meter interferometer proof-of-principle experiment

    CERN Document Server

    Gräf, C; Bell, A S; Campbell, F; Cumming, A V; Danilishin, S L; Gordon, N A; Hammond, G D; Hennig, J; Houston, E A; Huttner, S H; Jones, R A; Leavey, S S; Lück, H; Macarthur, J; Marwick, M; Rigby, S; Schilling, R; Sorazu, B; Spencer, A; Steinlechner, S; Strain, K A; Hild, S

    2014-01-01

    The second generation of large scale interferometric gravitational wave detectors will be limited by quantum noise over a wide frequency range in their detection band. Further sensitivity improvements for future upgrades or new detectors beyond the second generation motivate the development of measurement schemes to mitigate the impact of quantum noise in these instruments. Two strands of development are being pursued to reach this goal, focusing both on modifications of the well-established Michelson detector configuration and development of different detector topologies. In this paper, we present the design of the world's first Sagnac speed meter interferometer which is currently being constructed at the University of Glasgow. With this proof-of-principle experiment we aim to demonstrate the theoretically predicted lower quantum noise in a Sagnac interferometer compared to an equivalent Michelson interferometer, to qualify Sagnac speed meters for further research towards an implementation in a future genera...

  20. Hardware principles for the design of a stereo-matching state machine

    Directory of Open Access Journals (Sweden)

    J. A. Kalomiros

    2008-01-01

    Full Text Available This paper presents basic design principles for hardware implementation of a two-pass stereo-matching algorithm based on dynamic programming. For the first-pass a state-machine is proposed for the recursive calculation of the cost-function. The state-machine works along the diagonal of a 2-D disparity space for each epipolar pair of image scan-lines. On-chip local RAM stores tags that denote the minimum transition cost to every point in the disparity space among possible costs from all three neighboring points. All calculations are within a pre-determined useful disparity range. For the second pass, hardware rules are presented that produce the correct disparity per pixel, by backtracking stored cost values. Hard-ware stages are structured along a fully parallel pipeline, that outputs disparities in step with the input serial pixel stream at clock rate.

  1. Applying Semiotic Theories to Graphic Design Education: An Empirical Study on Poster Design Teaching

    Science.gov (United States)

    Yang, Chao-Ming; Hsu, Tzu-Fan

    2015-01-01

    The rationales behind design are dissimilar to those behind art. Establishing an adequate theoretical foundation for conducting design education can facilitate scientising design methods. Thus, from the perspectives of the semiotic theories proposed by Saussure and Peirce, we investigated graphic design curricula by performing teaching…

  2. Extending the generality of leaf economic design principles in the cycads, an ancient lineage.

    Science.gov (United States)

    Zhang, Yong-Jiang; Cao, Kun-Fang; Sack, Lawren; Li, Nan; Wei, Xue-Mei; Goldstein, Guillermo

    2015-04-01

    Cycads are the most ancient lineage of living seed plants, but the design of their leaves has received little study. We tested whether cycad leaves are governed by the same fundamental design principles previously established for ferns, conifers and angiosperms, and characterized the uniqueness of this relict lineage in foliar trait relationships. Leaf structure, photosynthesis, hydraulics and nutrient composition were studied in 33 cycad species from nine genera and three families growing in two botanical gardens. Cycads varied greatly in leaf structure and physiology. Similarly to other lineages, light-saturated photosynthetic rate per mass (Am ) was related negatively to leaf mass per area and positively to foliar concentrations of chlorophyll, nitrogen (N), phosphorus and iron, but unlike angiosperms, leaf photosynthetic rate was not associated with leaf hydraulic conductance. Cycads had lower photosynthetic N use efficiency and higher photosynthetic performance relative to hydraulic capacity compared with other lineages. These findings extend the relationships shown for foliar traits in angiosperms to the cycads. This functional convergence supports the modern synthetic understanding of leaf design, with common constraints operating across lineages, even as they highlight exceptional aspects of the biology of this key relict lineage. PMID:25622799

  3. Design concepts and principle of operation of the HeartWare ventricular assist system.

    Science.gov (United States)

    Larose, Jeffrey A; Tamez, Daniel; Ashenuga, Michael; Reyes, Carlos

    2010-01-01

    Implantable left ventricular assist devices provide circulatory support for patients at risk of death from refractory, end-stage heart failure. Rotary blood pumps have been designed for increased reliability and smaller size for use in a broader population of patients than the first-generation pulsatile devices. The design concepts and principle of operation of the HeartWare System are discussed. The HeartWare Ventricular Assist System (HVAD) is a small centrifugal flow pump with a displacement volume of 50 ml and an output capacity of 10 L/min. A unique wide-blade impeller is suspended by hybrid passive magnets and hydrodynamic forces. An integrated inflow cannula is inserted into the left ventricle and is held in position by an adjustable sewing ring; the pump is positioned in the pericardial space. The 10-mm outflow graft is anastomosed to the ascending aorta. External system components include the microprocessor-based controller, a monitor, lithium-ion battery packs, alternating current and direct current power adapters, and a battery charger. Physiologic control algorithms are incorporated for safe operation. Preclinical life cycle tests have shown the HVAD to be highly reliable. This system design offers reliability, portability, and ease of use for ambulatory patients. PMID:20559135

  4. Towards quantitative accuracy in first-principles transport calculations: The GW method applied to alkane/gold junctions

    DEFF Research Database (Denmark)

    Strange, Mikkel; Thygesen, Kristian Sommer

    2011-01-01

    The calculation of the electronic conductance of nanoscale junctions from first principles is a long-standing problem in the field of charge transport. Here we demonstrate excellent agreement with experiments for the transport properties of the gold/alkanediamine benchmark system when electron...... qualitatively different ways when the molecule is inserted in the junction. Consequently, the GW transport results cannot be mimicked by DFT calculations employing a simple scissors operator. © 2011 Strange and Thygesen; licensee Beilstein-Institut....

  5. Core Principles for Talent Management System and its Impact on Competitive Advantage "Applied Study Cellular Communications Companies in Jordan"

    OpenAIRE

    Mohammad Fathi Almaaitah; Yoshifumi Harada; Mohd Foad Bin Sakdan

    2015-01-01

    The aim of this study is to measure the core principles of talent management system and its impact on competitive advantage in Cellular communications companies in Jordan, The population of the study consisted of Three cellular telecom companies operating in the Jordanian market, the study sample was selected a random sample of employees in administrative levels: top management and middle management and supervisors in cellular communications companies operating in Jordan, and around include (...

  6. Applying Statistical Design to Control the Risk of Over-Design with Stochastic Simulation

    OpenAIRE

    Wu, Yi; Zhou, Peng; Lin, Jian; Qiu, Wanhua

    2010-01-01

    By comparing a hard real-time system and a soft real-time system, this article elicits the risk of over-design in soft real-time system designing. To deal with this risk, a novel concept of statistical design is proposed. The statistical design is the process accurately accounting for and mitigating the effects of variation in part geometry and other environmental conditions, while at the same time optimizing a target performance factor. However, statistical design can be a very difficult and...

  7. Design Principles of the Non-smooth Surface of Bionic Plow Moldboard

    Institute of Scientific and Technical Information of China (English)

    Luquan Ren; Shiqiao Deng; Jingchun Wang; Zhiwu Han

    2004-01-01

    The diverse non-smooth body surfaces to reduce soil adhesion are the evolutional results for the soil animals to fit the adhesive and wet environment and can be used as a biological basis for the design of bionic plow moldboard. The model surfaces for bionic simulation should be taken from soil animal digging organs, on which the soil motion is similar to what is on the surface of moldboard. By analyzing the distribution of non-smooth units on the body surface of the ground beetle jaw and the soil moving stresses, the design principles of the bionic moldboard for the local and the whole moldboard were presented respectively. As well, the effect of soil moving speed on reducing adhesion, the dimensions relationship between soil particles and non-smooth convexes, the relationship between the enveloping surface of non-smooth convexes and the initial smooth surface of the plow body, and the convex types of the sphere coronal and the pangolin scales, etc. were discussed.

  8. Design principles and field performance of a solar spectral irradiance meter

    Energy Technology Data Exchange (ETDEWEB)

    Tatsiankou, V.; Hinzer, K.; Haysom, J.; Schriemer, H.; Emery, K.; Beal, R.

    2016-08-01

    A solar spectral irradiance meter (SSIM), designed for measuring the direct normal irradiance (DNI) in six wavelength bands, has been combined with models to determine key atmospheric transmittances and the resulting spectral irradiance distribution of DNI under all sky conditions. The design principles of the SSIM, implementation of a parameterized transmittance model, and field performance comparisons of modeled solar spectra with reference radiometer measurements are presented. Two SSIMs were tested and calibrated at the National Renewable Energy Laboratory (NREL) against four spectroradiometers and an absolute cavity radiometer. The SSIMs' DNI was on average within 1% of the DNI values reported by one of NREL's primary absolute cavity radiometers. An additional SSIM was installed at the SUNLAB Outdoor Test Facility in September 2014, with ongoing collection of environmental and spectral data. The SSIM's performance in Ottawa was compared against a commercial pyrheliometer and a spectroradiometer over an eight month study. The difference in integrated daily spectral irradiance between the SSIM and the ASD spectroradiometer was found to be less than 1%. The cumulative energy density collected by the SSIM over this duration agreed with that measured by an Eppley model NIP pyrheliometer to within 0.5%. No degradation was observed.

  9. Ultra-high resolution flat-panel volume CT: fundamental principles, design architecture, and system characterization

    International Nuclear Information System (INIS)

    Digital flat-panel-based volume CT (VCT) represents a unique design capable of ultra-high spatial resolution, direct volumetric imaging, and dynamic CT scanning. This innovation, when fully developed, has the promise of opening a unique window on human anatomy and physiology. For example, the volumetric coverage offered by this technology enables us to observe the perfusion of an entire organ, such as the brain, liver, or kidney, tomographically (e.g., after a transplant or ischemic event). By virtue of its higher resolution, one can directly visualize the trabecular structure of bone. This paper describes the basic design architecture of VCT. Three key technical challenges, viz., scatter correction, dynamic range extension, and temporal resolution improvement, must be addressed for successful implementation of a VCT scanner. How these issues are solved in a VCT prototype and the modifications necessary to enable ultra-high resolution volumetric scanning are described. The fundamental principles of scatter correction and dose reduction are illustrated with the help of an actual prototype. The image quality metrics of this prototype are characterized and compared with a multi-detector CT (MDCT). (orig.)

  10. The Principle of the Micro-Electronic Neural Bridge and a Prototype System Design.

    Science.gov (United States)

    Huang, Zong-Hao; Wang, Zhi-Gong; Lu, Xiao-Ying; Li, Wen-Yuan; Zhou, Yu-Xuan; Shen, Xiao-Yan; Zhao, Xin-Tai

    2016-01-01

    The micro-electronic neural bridge (MENB) aims to rebuild lost motor function of paralyzed humans by routing movement-related signals from the brain, around the damage part in the spinal cord, to the external effectors. This study focused on the prototype system design of the MENB, including the principle of the MENB, the neural signal detecting circuit and the functional electrical stimulation (FES) circuit design, and the spike detecting and sorting algorithm. In this study, we developed a novel improved amplitude threshold spike detecting method based on variable forward difference threshold for both training and bridging phase. The discrete wavelet transform (DWT), a new level feature coefficient selection method based on Lilliefors test, and the k-means clustering method based on Mahalanobis distance were used for spike sorting. A real-time online spike detecting and sorting algorithm based on DWT and Euclidean distance was also implemented for the bridging phase. Tested by the data sets available at Caltech, in the training phase, the average sensitivity, specificity, and clustering accuracies are 99.43%, 97.83%, and 95.45%, respectively. Validated by the three-fold cross-validation method, the average sensitivity, specificity, and classification accuracy are 99.43%, 97.70%, and 96.46%, respectively. PMID:26276996

  11. Ultra-high resolution flat-panel volume CT: fundamental principles, design architecture, and system characterization

    Energy Technology Data Exchange (ETDEWEB)

    Gupta, Rajiv; Brady, Tom [Massachusetts General Hospital, Department of Radiology, Founders House, FND-2-216, Boston, MA (United States); Grasruck, Michael; Suess, Christoph; Schmidt, Bernhard; Stierstorfer, Karl; Popescu, Stefan; Flohr, Thomas [Siemens Medical Solutions, Forchheim (Germany); Bartling, Soenke H. [Hannover Medical School, Department of Neuroradiology, Hannover (Germany)

    2006-06-15

    Digital flat-panel-based volume CT (VCT) represents a unique design capable of ultra-high spatial resolution, direct volumetric imaging, and dynamic CT scanning. This innovation, when fully developed, has the promise of opening a unique window on human anatomy and physiology. For example, the volumetric coverage offered by this technology enables us to observe the perfusion of an entire organ, such as the brain, liver, or kidney, tomographically (e.g., after a transplant or ischemic event). By virtue of its higher resolution, one can directly visualize the trabecular structure of bone. This paper describes the basic design architecture of VCT. Three key technical challenges, viz., scatter correction, dynamic range extension, and temporal resolution improvement, must be addressed for successful implementation of a VCT scanner. How these issues are solved in a VCT prototype and the modifications necessary to enable ultra-high resolution volumetric scanning are described. The fundamental principles of scatter correction and dose reduction are illustrated with the help of an actual prototype. The image quality metrics of this prototype are characterized and compared with a multi-detector CT (MDCT). (orig.)

  12. Structural design principles for delivery of bioactive components in nutraceuticals and functional foods.

    Science.gov (United States)

    McClements, David Julian; Decker, Eric Andrew; Park, Yeonhwa; Weiss, Jochen

    2009-06-01

    There have been major advances in the design and fabrication of structured delivery systems for the encapsulation of nutraceutical and functional food components. A wide variety of delivery systems is now available, each with its own advantages and disadvantages for particular applications. This review begins by discussing some of the major nutraceutical and functional food components that need to be delivered and highlights the main limitations to their current utilization within the food industry. It then discusses the principles underpinning the rational design of structured delivery systems: the structural characteristics of the building blocks; the nature of the forces holding these building blocks together; and, the different ways of assembling these building blocks into structured delivery systems. Finally, we review the major types of structured delivery systems that are currently available to food scientists: lipid-based (simple, multiple, multilayer, and solid lipid particle emulsions); surfactant-based (simple micelles, mixed micelles, vesicles, and microemulsions) and biopolymer-based (soluble complexes, coacervates, hydrogel droplets, and particles). For each type of delivery system we describe its preparation, properties, advantages, and limitations. PMID:19484636

  13. Water, Resilience and the Law: From General Concepts and Governance Design Principles to Actionable Mechanisms

    Science.gov (United States)

    Hill Clarvis, M.; Allan, A.; Hannah, D. M.

    2013-12-01

    least data infrastructure. The article aims to contribute to both theory and practice, enabling policy makers to translate resilience based terminology and adaptive governance principles into clear instructions for incorporating uncertainty into legislation and policy design.

  14. How to Present Evidence-Based Usability Design Principles Dedicated to Medication-Related Alerting Systems to Designers and Evaluators? Results from a Workshop.

    Science.gov (United States)

    Marcilly, Romaric; Monkman, Helen; Villumsen, Sidsel; Kaufman, David; Beuscart-Zephir, Marie-Catherine

    2016-01-01

    Medication alerting system use errors and lack of adoption are often attributed to usability issues. Previous work has used evidence from the literature to reveal usability principles specific to medication alerting systems and identify potential consequences of violating these principles. The current study sought to explore how best to convey these principles to designers and evaluators of these systems to facilitate their work. To this aim, a workshop with 19 participants was used to generate ideas and opinions on how to deliver these topic-specific design principles in a way that would be most helpful for them. Participants generated ideas for how (e.g., a collaborative, continuously updated forum) and what (e.g., illustrations, checklists, evidence sources and strength, consequences of violations) information is most useful to disseminate usability principles for medication alerting systems. Participants, especially designers, expressed desire to use these principles in practice and avoid previously documented mistakes and therefore make design and evaluation of these systems more effective and efficient. Those insights are discussed in terms of feasibility and logistical challenges to developing the proposed documentation). To move this work forward, a more collaborative approach of Human Factors specialists in medical informatics is necessary. PMID:27577456

  15. Radiation physics and shielding codes and analyses applied to design-assist and safety analyses of CANDUR and ACRTM reactors

    International Nuclear Information System (INIS)

    This paper discusses the radiation physics and shielding codes and analyses applied in the design of CANDU and ACR reactors. The focus is on the types of analyses undertaken rather than the inputs supplied to the engineering disciplines. Nevertheless, the discussion does show how these analyses contribute to the engineering design. Analyses in radiation physics and shielding can be categorized as either design-assist or safety and licensing (accident) analyses. Many of the analyses undertaken are designated 'design-assist' where the analyses are used to generate recommendations that directly influence plant design. These recommendations are directed at mitigating or reducing the radiation hazard of the nuclear power plant with engineered systems and components. Thus the analyses serve a primary safety function by ensuring the plant can be operated with acceptable radiation hazards to the workers and public. In addition to this role of design assist, radiation physics and shielding codes are also deployed in safety and licensing assessments of the consequences of radioactive releases of gaseous and liquid effluents during normal operation and gaseous effluents following accidents. In the latter category, the final consequences of accident sequences, expressed in terms of radiation dose to members of the public, and inputs to accident analysis, e.g., decay heat in fuel following a loss-of-coolant accident, are also calculated. Another role of the analyses is to demonstrate that the design of the plant satisfies the principle of ALARA (as low as reasonably achievable) radiation doses. This principle is applied throughout the design process to minimize worker and public doses. The principle of ALARA is an inherent part of all design-assist recommendations and safety and licensing assessments. The main focus of an ALARA exercise at the design stage is to minimize the radiation hazards at the source. This exploits material selection and impurity specifications and relies

  16. Applying the proto-theory of design to explain and modify the parameter analysis method of conceptual design

    OpenAIRE

    Kroll, Ehud; Koskela, Lauri

    2016-01-01

    This article reports on the outcomes of applying the notions provided by the reconstructed proto-theory of design, based on Aristotle’s remarks, to the parameter analysis (PA) method of conceptual design. Two research questions are addressed: (1) What further clarification and explanation to the approach of PA is provided by the proto-theory? (2) Which conclusions can be drawn from the study of an empirically derived design approach through the proto-theory regarding usefulness, validity a...

  17. Development of next generation digital flat panel catheterization system: design principles and validation methodology

    Science.gov (United States)

    Belanger, B.; Betraoui, F.; Dhawale, P.; Gopinath, P.; Tegzes, Pal; Vagvolgyi, B.

    2006-03-01

    The design principles that drove the development of a new cardiovascular x-ray digital flat panel (DFP) detector system are presented, followed by assessments of imaging and dose performance achieved relative to other state of the art FPD systems. The new system (GE Innova 2100 IQ TM) incorporates a new detector with substantially improved DQE at fluoroscopic (73%@1μR) and record (79%@114uR) doses, an x-ray tube with higher continuous fluoro power (3.2kW), a collimator with a wide range of copper spectral filtration (up to 0.9mm), and an improved automatic x-ray exposure management system. The performance of this new system was compared to that of the previous generation GE product (Innova 2000) and to state-of-the art cardiac digital x-ray flat panel systems from two other major manufacturers. Performance was assessed with the industry standard Cardiac X-ray NEMA/SCA and I phantom, and a new moving coronary artery stent (MCAS) phantom, designed to simulate cardiac clinical imaging conditions, composed of an anthropomorphic chest section with stents moving in a manner simulating normal coronary arteries. The NEMA/SCA&I phantom results showed the Innova 2100 IQ to exceed or equal the Innova 2000 in all of the performance categories, while operating at 28% lower dose on average, and to exceed the other DFP systems in most of the performance categories. The MCAS phantom tests showed the Innova 2100 IQ to be significantly better (p << 0.05) than the Innova 2000, and significantly better than the other DFP systems in most cases at comparable or lower doses, thereby verifying excellent performance against design goals.

  18. First-principles material design and perspective on semiconductor spintronics materials

    International Nuclear Information System (INIS)

    We investigate the electronic structure and magnetic properties of III-V compound semiconductor based dilute magnetic semiconductors (DMS) from first-principles. The electronic structure of DMS is calculated by using the Korringa-Kohn-Rostoker coherent potential approximation (KKR-CPA) method in connection with the local density approximation (LDA). Describing the magnetic properties by a classical Heisenberg model, effective exchange interactions are calculated by applying magnetic force theorem for two impurities embedded in the CPA medium. With the calculated exchange interactions, TC is estimated by using the mean field approximation, the random phase approximation and the Monte Carlo simulation. In the above compounds, the magnetic interactions are well described from double exchange picture. Due to the short-range interactions, high-TC is difficult to achieve in the presently investigated materials. Based on the present results, two strategies towards high-TC are proposed to realize useful DMS materials. One uses spinodal decomposition to realize high blocking temperature in super-paramagnetic blocking phenomena and the other uses co-doping method to realize high concentration doping of magnetic impurities for high-TC.

  19. Applying Universal Design to Disability Service Provision: Outcome Analysis of a Universal Design (UD) Audit

    Science.gov (United States)

    Beck, Tanja; Diaz del Castillo, Patricia; Fovet, Frederic; Mole, Heather; Noga, Brodie

    2014-01-01

    This article presents out an outcome analysis of a Universal Design (UD) audit to the various professional facets of a disability service (DS) provider's office on a large North American campus. The context of the audit is a broad campus-wide drive to implement Universal Design for Learning (UDL) in teaching practices. In an effort for…

  20. Canadian nuclear power principles for beyond design basis events - supporting rationale

    International Nuclear Information System (INIS)

    The development of the following principles and their rationale began during a special Chief Nuclear Engineers forum held on March 25th, 2013 in Toronto. These principles are intended to provide guidance to the Canadian Nuclear Power Industry in developing responses to the lessons learned from the Fukushima event of March 2011. These principles were accepted and signed off by the Chief Nuclear Officers of each of the three utilities in August 2013 and were presented to the CNSC at a public hearing on August 21, 2013. This document provides the underlying rationale for the principles. (author)

  1. EFSA Panel on Dietetic Products, Nutrition, and Allergies (NDA); Scientific Opinion on principles for deriving and applying Dietary Reference Values

    DEFF Research Database (Denmark)

    Tetens, Inge

    This Opinion of the EFSA Panel on Dietetic products, Nutrition, and Allergies (NDA) deals with the general principles for development and application of Dietary Reference Values (DRVs). These quantitative reference values for nutrient intakes for healthy individuals and populations are based on...... health criteria. Derived from DRVs, nutrients goals and recommendations take into account other criteria such as food composition or dietary habits, and may be used for assessment and planning of diets. It is proposed to derive the following DRVs: 1) Population Reference Intakes (PRI), 2) Average...... Requirement (AR), 3) Lower Threshold Intake (LTI), 4) Adequate Intake (AI), 5) Reference Intake ranges for macronutrients (RI). Nutrient requirements differ with age, sex and physiological condition. The Panel proposes to define the age ranges used for each nutrient on a case-by-case basis depending on the...

  2. Design principles for maximizing photovoltage in metal-oxide-protected water-splitting photoanodes

    Science.gov (United States)

    Scheuermann, Andrew G.; Lawrence, John P.; Kemp, Kyle W.; Ito, T.; Walsh, Adrian; Chidsey, Christopher E. D.; Hurley, Paul K.; McIntyre, Paul C.

    2016-01-01

    Metal oxide protection layers for photoanodes may enable the development of large-scale solar fuel and solar chemical synthesis, but the poor photovoltages often reported so far will severely limit their performance. Here we report a novel observation of photovoltage loss associated with a charge extraction barrier imposed by the protection layer, and, by eliminating it, achieve photovoltages as high as 630 mV, the maximum reported so far for water-splitting silicon photoanodes. The loss mechanism is systematically probed in metal-insulator-semiconductor Schottky junction cells compared to buried junction p+n cells, revealing the need to maintain a characteristic hole density at the semiconductor/insulator interface. A leaky-capacitor model related to the dielectric properties of the protective oxide explains this loss, achieving excellent agreement with the data. From these findings, we formulate design principles for simultaneous optimization of built-in field, interface quality, and hole extraction to maximize the photovoltage of oxide-protected water-splitting anodes.

  3. Structural design principles of complex bird songs: a network-based approach.

    Directory of Open Access Journals (Sweden)

    Kazutoshi Sasahara

    Full Text Available Bird songs are acoustic communication signals primarily used in male-male aggression and in male-female attraction. These are often monotonous patterns composed of a few phrases, yet some birds have extremely complex songs with a large phrase repertoire, organized in non-random fashion with discernible patterns. Since structure is typically associated with function, the structures of complex bird songs provide important clues to the evolution of animal communication systems. Here we propose an efficient network-based approach to explore structural design principles of complex bird songs, in which the song networks--transition relationships among different phrases and the related structural measures--are employed. We demonstrate how this approach works with an example using California Thrasher songs, which are sequences of highly varied phrases delivered in succession over several minutes. These songs display two distinct features: a large phrase repertoire with a 'small-world' architecture, in which subsets of phrases are highly grouped and linked with a short average path length; and a balanced transition diversity amongst phrases, in which deterministic and non-deterministic transition patterns are moderately mixed. We explore the robustness of this approach with variations in sample size and the amount of noise. Our approach enables a more quantitative study of global and local structural properties of complex bird songs than has been possible to date.

  4. Design of a speed meter interferometer proof-of-principle experiment

    International Nuclear Information System (INIS)

    The second generation of large scale interferometric gravitational wave (GW) detectors will be limited by quantum noise over a wide frequency range in their detection band. Further sensitivity improvements for future upgrades or new detectors beyond the second generation motivate the development of measurement schemes to mitigate the impact of quantum noise in these instruments. Two strands of development are being pursued to reach this goal, focusing both on modifications of the well-established Michelson detector configuration and development of different detector topologies. In this paper, we present the design of the world's first Sagnac speed meter (SSM) interferometer, which is currently being constructed at the University of Glasgow. With this proof-of-principle experiment we aim to demonstrate the theoretically predicted lower quantum noise in a Sagnac interferometer compared to an equivalent Michelson interferometer, to qualify SSM for further research towards an implementation in a future generation large scale GW detector, such as the planned Einstein telescope observatory. (paper)

  5. Applying Design Research Artifacts for Building Design Research Artifacts: A Process Model for Enterprise Architecture Planning

    OpenAIRE

    Aier, Stephan; Gleichauf, Bettina

    2010-01-01

    Enterprise architecture (EA) describes the fundamental structure of an organization from business to IT. EA as a practice as well as a research topic has been around for several years. However, existing methods largely neglect the existence of time which is essential in order to systematically approach EA planning. The article at hand builds a process model for EA planning as a de-sign research artifact. We therefore use another more general design research artifact a method for process engi...

  6. The principles of designing of algorithm for speech synthesis from texts written in Albanian language

    Directory of Open Access Journals (Sweden)

    Agni Dika

    2012-05-01

    Full Text Available The speech synthesis is artificial generation of human speech from written texts. For this purpose, adequate algorithms are designed, which then through relevant programs make it possible to synthesize texts to speech. The process of converting text into speech is also known as Text-To-Speech (TTS system [5]. In this paper are given basic principles to be used when designing a system to synthesize speech in Albanian language from written texts. Currently there are solutions that enable natural speech generation for various world languages. However, unfortunately these are not universal solutions to be used for other languages too, because the volume generated for other languages is incomprehensible and unnatural. For this reason, for every language one should seek solutions that address the specifics of it, always with the aim of generating voice to suit the nature of language. Generating systems that are currently used mainly rely on the use of the concatenation method [6], during which acoustic segments of text files are joined, which are previously digitized and stored as such in a database. For Albanian language, we consider that on the textual part of the database, as basic segments to be used are: the most frequent words, two-letters and letters [4]. However, in a particular part of the database are included various abbreviations, i.e. textual equivalents and their acoustics files, to be used also during the generation of appropriate speech. Whereas, with the aim of synthesizing the various numerical values written in the decimal system, in database were added values, respectively their corresponding sound files, whereby speech is generated for different numbers. The first part of the paper is a brief presentation of the Albanian language [1], respectively of the alphabet used in writing the language and its most frequent words.

  7. PRINCIPLES AND PARAMETER DESIGN FOR AC-DC THREE-DEGREE FREEDOM HYBRID MAGNETIC BEARINGS

    Institute of Scientific and Technical Information of China (English)

    ZHU Huangqiu; XIE Zhiyi; ZHU Dehong

    2006-01-01

    To simplify the mechanical structure, decrease the overall system size of the 3-degree freedom axial-radial magnetic bearings and reduce the manufacturing costs as well as operating costs,an innovated AC-DC 3-degree freedom hybrid magnetic bearing is proposed, which is driven by a DC amplifier in axial direction and a 3-phase power converter in radial directions respectively, and the axial and radial bias magnetic fluxes are provided with a common radial polarized permanent magnet ring. The principle producing magnetic suspension forces is introduced. By using equivalent magnetic circuit method, the calculation formulas of magnetic suspension forces and the mathematics models of the system are deduced. Nonlinearities of suspension forces and cross coupling between different degree freedoms are studied further by calculating the suspension forces at different displacements and control currents to validate the feasibility of the mathematics model. Then based on the mathematics models of the bearing, a control method of this novel bearing is designed. Lastly, the methods on parameter design and calculations of the bearing are presented, and an applicable prototype is simulated to analyze the magnetic path by using finite element analysis. The theory analysis and simulation results have shown that this magnetic bearing incorporates the merits of 3-phase AC drive, permanent magnet flux biased and axial-radial combined control, and reduces overall system size and has higher efficiency and lower cost. This innovated magnetic bearing has a wide application in super-speed and super-precision numerical control machine tools, bearingless motors, high-speed flywheels, satellites, etc.

  8. Design, implementation, and evaluation of principles of writing biomedical research paper course

    Directory of Open Access Journals (Sweden)

    ALI AKBAR NEKOOEIAN

    2013-10-01

    Full Text Available Introduction: Graduate (PhD students in medical sciences, who will form future faculties and investigators in Iran’s Universities of Medical Sciences, are not trained on scientific writing during their training. The present study describes the design, implementation, and evaluation of Principles of Writing Biomedical Research Paper course. Methods: The course, prepared based on an extensive search of the literature and books on writing biomedical research papers, was offered as an elective course to PhD students at Shiraz University of Medical Sciences in the second semester of 2011-2012 academic year. The structure and function of various sections of a paper and publication ethics were discussed in lecture and practical sessions over a period of 12 weeks. The course was then evaluated using a self-designed questionnaire. Results: The majority of students gave the highest score (20 to the content and implementation of all sessions of the course. Moreover, most of them believed that the allotted time to the course was not enough, and suggested that it should be increased to 32 hours (equal to two credits. Also, almost all the participants believed that overall the materials lectured were comprehensive, the practical sessions were important in learning the lectured materials, and the course was useful in advancing their abilities and skills to write papers. Conclusion: The evaluation of the present course showed that it was able to increase the participants’ knowledge of the structure of scientific papers, and enhanced their abilities and skills to write papers. The evaluation was used as a basis to modify the course.

  9. Principles for Designing an AI Competition, or Why the Turing Test Fails as an Inducement Prize

    OpenAIRE

    Shieber, Stuart M.; AAAI

    2016-01-01

    If the artificial intelligence research community is to have a challenge problem as an incentive for research, as many have called for, it behooves us to learn the principles of past successful inducement prize competitions. Those principles argue against the Turing test proper as an appropriate task, despite its appropriateness as a criterion (perhaps the only one) for attributing intelligence to a machine.

  10. What Can Librarians Learn from Elmo, Sid, and Dora? Applying the Principles of Educational Television to Storytime

    Science.gov (United States)

    Cahill, Maria; Bigheart, Jennifer

    2016-01-01

    Parents and caregivers can maximize children's engagement with educational television programming by co-viewing and discussing concepts and issues during and following episodes, and parents and caregivers can poach ideas and processes from these programs and apply them to their own interactions with children. School librarians might also consider…

  11. Employing the Principles of Universal Design for Learning to Deconstruct the Greek-Cypriot New National Curriculum

    Science.gov (United States)

    Mavrou, Katerina; Symeonidou, Simoni

    2014-01-01

    The present paper discusses issues related to inclusive education and curricula development based on the principles of universal design for learning (UDL), and it reports on the results of a qualitative content analysis of the new national curriculum (NNC) developed for the public Greek-Cypriot schools in Cyprus. According to the findings, the NNC…

  12. The Influence of the Instruction of Visual Design Principles on Improving Pre-Service Teachers' Visual Literacy

    Science.gov (United States)

    Yeh, Hsin-Te; Cheng, Yi-Chia

    2010-01-01

    This study investigated whether the instruction of visual design principles had an influence on pre-service teachers' perception and analysis (interpretation) of visual materials. In addition, the relationships between pre-service teachers' visual intelligence and their perception and analysis (interpretation) of visual materials were also…

  13. Critical Curriculum Design for Blended Learning in Higher Education: The Strategies, Principles and Challenges of Interactive Classroom Management

    Science.gov (United States)

    Kurubacak, Gulsun

    2006-01-01

    The main purpose of this article is to introduce a critical curriculum design approach for bringing curriculum change for Blended Learning in higher education. Furthermore, the strategies, principles and challenges of this approach are also presented. This paper provides a perspective on such serious concerns as whether curriculum change should…

  14. Principles of Course Design for Language Teaching and Its Implications to TEFL Reform in Higher Vocational Colleges

    Institute of Scientific and Technical Information of China (English)

    刘彦臻

    2013-01-01

      Principles of Course Design for Language Teaching by Janice Yalden is a linguistics book for the ESL/EFL teachers and researchers. By briefing and analyzing the contents , some guidelines and methods are found practical and enlightening for the teachers in higher vocational college to develop EFL courses.

  15. CALL Design: Principles and Practice. Proceedings of the 2014 EUROCALL Conference (Groningen, The Netherlands, August 20-23, 2014)

    Science.gov (United States)

    Jager, Sake, Ed.; Bradley, Linda, Ed.; Meima, Estelle J., Ed.; Thouësny, Sylvie, Ed.

    2014-01-01

    The theme of EUROCALL 2014 was "CALL Design: Principles and Practice," which attracted approximately 280 practitioners, researchers and students from computer-assisted language learning (CALL) and related disciplines of more than 40 different nationalities. Over 170 presentations were delivered on topics related to this overarching…

  16. Shark, new motor design concept for energy saving applied to switched reluctance motor

    Energy Technology Data Exchange (ETDEWEB)

    Tataru Kjaer, A.M.

    2005-07-01

    The aim of this thesis is to document and promote a relatively new concept of designing electrical machine with improved efficiency, without using more or better material. The concept, called Shark, consists in replacing the cylindrical air gap by a non-linear shape obtained by translating specific geometrical pattern on the longitudinal axis of the electrical machine. This shape modification increases the air gap area and thus the energy conversion, taking place in the machine. Whilst other methods of improving the efficiency consider the use of more and/or better magnetic material and/or optimisation of the magnetic circuit of the radial cross-section of the machine, the proposed method makes use of the longitudinal cross-section of the machine. In spite of a few reports claiming the improvement of the efficiency by applying the optimisation of the longitudinal cross-section, none analysis of various air gap shapes and of their influence on the magnetic performance has been reported. Due to a simple geometry, the Switched Reluctance Machine has been selected for demonstration of the Shark principle. Initially, linear and finite element analyses are considered. They provide the basic knowledge of the manner in which various Shark air gap, having different dimensions, influence the energy conversion in the machine. The saturation mechanisms, specific to each Shark profile are analysed and optimum Shark profile and its dimensions are selected for implementation in a demonstration machine. Due to the lack of quick analysis tools, an analytical model of the Shark Switched Reluctance Machine is also proposed in this thesis. This model is conceived by modifying one of the existing models of cylindrical air gap Switched Reluctance Machines, such as to account for the presence of the Shark profiles in the air gap. The calculations are verified by measurement on two demonstration machines, having cylindrical and Shark air gaps. The measurement proved the theory right and

  17. Elution by Le Chatelier's principle for maximum recyclability of adsorbents: applied to polyacrylamidoxime adsorbents for extraction of uranium from seawater.

    Science.gov (United States)

    Oyola, Yatsandra; Vukovic, Sinisa; Dai, Sheng

    2016-05-28

    Amidoxime-based polymer adsorbents have attracted interest within the last decade due to their high adsorption capacities for uranium and other rare earth metals from seawater. The ocean contains an approximated 4-5 billion tons of uranium and even though amidoxime-based adsorbents have demonstrated the highest uranium adsorption capacities to date, they are still economically impractical because of their limited recyclability. Typically, the adsorbed metals are eluted with a dilute acid solution that not only damages the amidoxime groups (metal adsorption sites), but is also not strong enough to remove the strongly bound vanadium, which decreases the adsorption capacity with each cycle. We resolved this challenge by incorporating Le Chatelier's principle to recycle adsorbents indefinitely. We used a solution with a high concentration of amidoxime-like chelating agents, such as hydroxylamine, to desorb nearly a 100% of adsorbed metals, including vanadium, without damaging the metal adsorption sites and preserving the high adsorption capacity. The method takes advantage of knowing the binding mode between the amidoxime ligand and the metal and mimics it with chelating agents that then in a Le Chatelier's manner removes metals by shifting to a new chemical equilibrium. For this reason the method is applicable to any ligand-metal adsorbent and it will make an impact on other extraction technologies. PMID:27117598

  18. Applying Instructional Design Theories to Bioinformatics Education in Microarray Analysis and Primer Design Workshops

    Science.gov (United States)

    Shachak, Aviv; Ophir, Ron; Rubin, Eitan

    2005-01-01

    The need to support bioinformatics training has been widely recognized by scientists, industry, and government institutions. However, the discussion of instructional methods for teaching bioinformatics is only beginning. Here we report on a systematic attempt to design two bioinformatics workshops for graduate biology students on the basis of…

  19. Design Principles and Case Study Analysis for Low Impact Development Practices - Green Roofs, Rainwater Harvesting and Vegetated Swales

    OpenAIRE

    Ramesh, Shalini

    2011-01-01

    This thesis on Low Impact Development (LID) Practices provides design guidelines and principles for three important LID practices: green roofs, rainwater harvesting and bioswales. The most important component of the thesis is the qualitative analysis of various case studies based on the LID objectives drawn from the literature review for each LID practice. Through the course of my research, I found that there was no one single source which provided information on the design guidelines acc...

  20. A REVIEW ON USER INTERFACE DESIGN PRINCIPLES TO INCREASE SOFTWARE USABILITY FOR USERS WITH LESS COMPUTER LITERACY

    OpenAIRE

    Ali Darejeh; Dalbir Singh

    2013-01-01

    This article presents a review on how software usability could be increased for users with less computer literacy. The literature was reviewed to extract user interface design principles by identifying the similar problems of this group of users. There are different groups of users with less computer literacy. However, based on the literature three groups of them need special attention from software designers. The first group is elderly users, as users with lack of computer background. The se...