Sample records for applied approaches modelisation

  1. Comparison of ensemble post-processing approaches, based on empirical and dynamical error modelisation of rainfall-runoff model forecasts (United States)

    Chardon, J.; Mathevet, T.; Le Lay, M.; Gailhard, J.


    In the context of a national energy company (EDF : Electricité de France), hydro-meteorological forecasts are necessary to ensure safety and security of installations, meet environmental standards and improve water ressources management and decision making. Hydrological ensemble forecasts allow a better representation of meteorological and hydrological forecasts uncertainties and improve human expertise of hydrological forecasts, which is essential to synthesize available informations, coming from different meteorological and hydrological models and human experience. An operational hydrological ensemble forecasting chain has been developed at EDF since 2008 and is being used since 2010 on more than 30 watersheds in France. This ensemble forecasting chain is characterized ensemble pre-processing (rainfall and temperature) and post-processing (streamflow), where a large human expertise is solicited. The aim of this paper is to compare 2 hydrological ensemble post-processing methods developed at EDF in order improve ensemble forecasts reliability (similar to Monatanari &Brath, 2004; Schaefli et al., 2007). The aim of the post-processing methods is to dress hydrological ensemble forecasts with hydrological model uncertainties, based on perfect forecasts. The first method (called empirical approach) is based on a statistical modelisation of empirical error of perfect forecasts, by streamflow sub-samples of quantile class and lead-time. The second method (called dynamical approach) is based on streamflow sub-samples of quantile class and streamflow variation, and lead-time. On a set of 20 watersheds used for operational forecasts, results show that both approaches are necessary to ensure a good post-processing of hydrological ensemble, allowing a good improvement of reliability, skill and sharpness of ensemble forecasts. The comparison of the empirical and dynamical approaches shows the limits of the empirical approach which is not able to take into account hydrological

  2. Modelisation of the SECMin molten salts environment (United States)

    Lucas, M.; Slim, C.; Delpech, S.; di Caprio, D.; Stafiej, J.


    We develop a cellular automata modelisation of SECM experiments to study corrosion in molten salt media for generation IV nuclear reactors. The electrodes used in these experiments are cylindrical glass tips with a coaxial metal wire inside. As the result of simulations we obtain the current approach curves of the electrodes with geometries characterized by several values of the ratios of glass to metal area at the tip. We compare these results with predictions of the known analytic expressions, solutions of partial differential equations for flat uniform geometry of the substrate. We present the results for other, more complicated substrate surface geometries e. g. regular saw modulated surface, surface obtained by Eden model process, ...

  3. Apply the Communicative Approach in Listening Class

    Institute of Scientific and Technical Information of China (English)

    Wang; changxue; Su; na


    Speaking and listening are the two obstacles in the process of our learning and they are also the most important abilities that we should possess. Communicative approach aims to the ability of learners’ communicative competence, thus apply the communicative approach in listening class is an effective way in English teaching procedure.

  4. Apply the Communicative Approach in Listening Class

    Institute of Scientific and Technical Information of China (English)

    Wang changxue; Su na


    Speaking and listening are the two obstacles in the process of our learning and they are also the most important abilities that we should possess. Communicative approach aims to the ability of learners’communicative competence, thus apply the communicative approach in listening class is an effective way in English teaching procedure.

  5. Reflector modelization in neutronic and optimization methods applied to fuel loading pattern; Modelisation du reflecteur en neutronique et methodes d`optimisation appliquees aux plans de rechargement

    Energy Technology Data Exchange (ETDEWEB)

    Argaud, J.P.


    I Physical description of P.W.R nuclear core can be handled by multigroup neutronic diffusion model. We are interested in two problems, using the same approach for the optimization aspect. To deal with some differences between calculations and measurements, the question of their reduction is then introduced. A reflector parameters identification from core measurements is then purposed, the reflector being at the present time the less known part of core diffusion model. This approach conducts to study the reflector model, in particular by an analysis of its transport origin. It leads finally to a new model of reflector described by boundary operators using an integral formulation on the core/reflector interface. That is on this new model that a parameter identification formulation of calculations-measurements differences reduction is given, using an adjoint state formulation to minimize errors by a gradient method. Furthermore, nuclear fuel reload of P.W.R core needs an optimal distribution of fuel assemblies, namely a loading pattern. This combinatorial optimization problem is then expressed as a cost function minimization, the cost function describing the power spatial distribution. Various methods (linear programming, simulated annealing,...), used to solve this problem, are detailed, given in particular a practical search example. A new approach is then proposed, using the gradient of the cost function to direct the search in the patterns discrete space. Final results of complete patterns search trials are presented, and compared to those obtained by other methods. In particular the results are obtained very quickly. (author). 81 refs., 55 figs., 5 appends.

  6. Applying SF-Based Genre Approaches to English Writing Class (United States)

    Wu, Yan; Dong, Hailin


    By exploring genre approaches in systemic functional linguistics and examining the analytic tools that can be applied to the process of English learning and teaching, this paper seeks to find a way of applying genre approaches to English writing class.

  7. Applying a managerial approach to day surgery. (United States)

    Onetti, Alberto


    The present article explores the day surgery topic assuming a managerial perspective. If we assume such a perspective, day surgery can be considered as a business model decision care and not just a surgical procedure alternative to the traditional ones requiring patient hospitalization. In this article we highlight the main steps required to develop a strategic approach [Cotta Ramusino E, Onetti A. Strategia d'Impresa. Milano; Il Sole 24 Ore; Second Edition, 2007] at hospital level (Onetti A, Greulich A. Strategic management in hospitals: the balanced scorecard approach. Milano: Giuffé; 2003) and to make day surgery part of it. It means understanding: - how and when day surgery can improve the health care providers' overall performance both in terms of clinical effectiveness and financial results, and, - how to organize and integrate it with the other hospital activities in order to make it work. Approaching day surgery as a business model decision requires to address in advance a list of potential issues and necessitates of continued audit to verify the results. If it does happen, day surgery can be both safe and cost effective and impact positively on surgical patient satisfaction. We propose a sort of "check-up list" useful to hospital managers and doctors that are evaluating the option of introducing day surgery or are trying to optimize it.

  8. Applying a gaming approach to IP strategy. (United States)

    Gasnier, Arnaud; Vandamme, Luc


    Adopting an appropriate IP strategy is an important but complex area, particularly in the pharmaceutical and biotechnology sectors, in which aspects such as regulatory submissions, high competitive activity, and public health and safety information requirements limit the amount of information that can be protected effectively through secrecy. As a result, and considering the existing time limits for patent protection, decisions on how to approach IP in these sectors must be made with knowledge of the options and consequences of IP positioning. Because of the specialized nature of IP, it is necessary to impart knowledge regarding the options and impact of IP to decision-makers, whether at the level of inventors, marketers or strategic business managers. This feature review provides some insight on IP strategy, with a focus on the use of a new 'gaming' approach for transferring the skills and understanding needed to make informed IP-related decisions; the game Patentopolis is discussed as an example of such an approach. Patentopolis involves interactive activities with IP-related business decisions, including the exploitation and enforcement of IP rights, and can be used to gain knowledge on the impact of adopting different IP strategies.

  9. Applied Regression Modeling A Business Approach

    CERN Document Server

    Pardoe, Iain


    An applied and concise treatment of statistical regression techniques for business students and professionals who have little or no background in calculusRegression analysis is an invaluable statistical methodology in business settings and is vital to model the relationship between a response variable and one or more predictor variables, as well as the prediction of a response value given values of the predictors. In view of the inherent uncertainty of business processes, such as the volatility of consumer spending and the presence of market uncertainty, business professionals use regression a

  10. Experimental approach and micro-mechanical modeling of the mechanical behavior of irradiated zirconium alloys; Approche experimentale et modelisation micromecanique du comportement des alliages de zirconium irradies

    Energy Technology Data Exchange (ETDEWEB)

    Onimus, F


    Zirconium alloys cladding tubes containing nuclear fuel of the Pressurized Water Reactors constitute the first safety barrier against the dissemination of radioactive elements. Thus, it is essential to predict the mechanical behavior of the material in-reactor conditions. This study aims, on the one hand, to identify and characterize the mechanisms of the plastic deformation of irradiated zirconium alloys and, on the other hand, to propose a micro-mechanical modeling based on these mechanisms. The experimental analysis shows that, for the irradiated material, the plastic deformation occurs by dislocation channeling. For transverse tensile test and internal pressure test this channeling occurs in the basal planes. However, for axial tensile test, the study revealed that the plastic deformation also occurs by channeling but in the prismatic and pyramidal planes. In addition, the study of the macroscopic mechanical behavior, compared to the deformation mechanisms observed by TEM, suggested that the internal stress is higher in the case of irradiated material than in the case of non-irradiated material, because of the very heterogeneous character of the plastic deformation. This analysis led to a coherent interpretation of the mechanical behavior of irradiated materials, in terms of deformation mechanisms. The mechanical behavior of irradiated materials was finally modeled by applying homogenization methods for heterogeneous materials. This model is able to reproduce adequately the mechanical behavior of the irradiated material, in agreement with the TEM observations. (author)

  11. Critical Applied Linguistics: An Evaluative Interdisciplinary Approach in Criticism and Evaluation of Applied Linguistics’ Disciplines

    Directory of Open Access Journals (Sweden)

    H. Davari


    Full Text Available The emergence of some significant critical approaches and directions in the field of applied linguistics from the mid-1980s onwards has met with various positive and opposite reactions. On the basis of their strength and significance, such approaches and directions have challenged some of the mainstream approaches’ claims, principles and assumptions. Among them, critical applied linguistics can be highlighted as a new approach, developed by the Australian applied linguist, Alastair Pennycook. The aspects, domains and concerns of this new approach were introduced in his book in 2001. Due to the undeniable importance of this approach, as well as partial negligence regarding it in Iranian academic setting, this paper first intends to introduce this approach, as an approach that evaluates various disciplines of applied linguistics through its own specific principles and interests. Then, in order to show its step-by-step application in the evaluation of different disciplines of applied linguistics, with a glance at its significance and appropriateness in Iranian society, two domains, namely English language education and language policy and planning, are introduced and evaluated in order to provide readers with a visible and practical picture of its interdisciplinary nature and evaluative functions. The findings indicate the efficacy of applying this interdisciplinary framework in any language-in-education policy and planning in accordance with the political, social and cultural context of the target society.

  12. Focus Groups: A Practical and Applied Research Approach for Counselors (United States)

    Kress, Victoria E.; Shoffner, Marie F.


    Focus groups are becoming a popular research approach that counselors can use as an efficient, practical, and applied method of gathering information to better serve clients. In this article, the authors describe focus groups and their potential usefulness to professional counselors and researchers. Practical implications related to the use of…

  13. Classical mechanics approach applied to analysis of genetic oscillators. (United States)

    Vasylchenkova, Anastasiia; Mraz, Miha; Zimic, Nikolaj; Moskon, Miha


    Biological oscillators present a fundamental part of several regulatory mechanisms that control the response of various biological systems. Several analytical approaches for their analysis have been reported recently. They are, however, limited to only specific oscillator topologies and/or to giving only qualitative answers, i.e., is the dynamics of an oscillator given the parameter space oscillatory or not. Here we present a general analytical approach that can be applied to the analysis of biological oscillators. It relies on the projection of biological systems to classical mechanics systems. The approach is able to provide us with relatively accurate results in the meaning of type of behaviour system reflects (i.e. oscillatory or not) and periods of potential oscillations without the necessity to conduct expensive numerical simulations. We demonstrate and verify the proposed approach on three different implementations of amplified negative feedback oscillator.

  14. Applying a weed risk assessment approach to GM crops. (United States)

    Keese, Paul K; Robold, Andrea V; Myers, Ruth C; Weisman, Sarah; Smith, Joe


    Current approaches to environmental risk assessment of genetically modified (GM) plants are modelled on chemical risk assessment methods, which have a strong focus on toxicity. There are additional types of harms posed by plants that have been extensively studied by weed scientists and incorporated into weed risk assessment methods. Weed risk assessment uses robust, validated methods that are widely applied to regulatory decision-making about potentially problematic plants. They are designed to encompass a broad variety of plant forms and traits in different environments, and can provide reliable conclusions even with limited data. The knowledge and experience that underpin weed risk assessment can be harnessed for environmental risk assessment of GM plants. A case study illustrates the application of the Australian post-border weed risk assessment approach to a representative GM plant. This approach is a valuable tool to identify potential risks from GM plants.

  15. Modelisation of leukocyte adhesion on a fibrinogen coated surface in static conditions. (United States)

    Labrador, V; Legrand, S; Muller, S; Carl, P; Senger, B; Voegel, J C; Latger-Cannard, V; Stoltz, J F


    The adhesion of polymorphonuclear leukocytes (PMNs) on the vascular endothelium is a complex process that occurs during biological and pathological events and involves a large family of molecules. This phenomenom could be approached by a modelisation study of the adhesion of PMNs on a biological substrate, fibrinogen. Two different physiological conditions were tested such as the activated state of PMNs with a synthetic pro-inflammatory activator (N-Formyl-Methionyl-Leucyl-Phenylalanine, FMLP). The activated state of PMNs was both quantified by flow cytometry and controlled by fluorescence microscopy. The results suggest that quiescent PMNs deposit in accordance with the ballistic deposition model. The preliminary results obtained with FMLP-stimulated PMNs show a different deposit process compared to quiescent PMNs but do not allow to determine exactly a deposition model.

  16. Image-Based Learning Approach Applied to Time Series Forecasting

    Directory of Open Access Journals (Sweden)

    J. C. Chimal-Eguía


    Full Text Available In this paper, a new learning approach based on time-series image information is presented. In order to implementthis new learning technique, a novel time-series input data representation is also defined. This input datarepresentation is based on information obtained by image axis division into boxes. The difference between this newinput data representation and the classical is that this technique is not time-dependent. This new information isimplemented in the new Image-Based Learning Approach (IBLA and by means of a probabilistic mechanism thislearning technique is applied to the interesting problem of time series forecasting. The experimental results indicatethat by using the methodology proposed in this article, it is possible to obtain better results than with the classicaltechniques such as artificial neuronal networks and support vector machines.

  17. Guiding Mobile Robot by Applying Fuzzy Approach on Sonar Sensors

    Directory of Open Access Journals (Sweden)

    Ahmed Rahman Jasim


    Full Text Available This study describes how fuzzy logic control FLC can be applied to sonars of mobile robot. The fuzzy logic approach has effects on the navigation of mobile robots in a partially known environment that are used in different industrial and society applications. The fuzzy logic provides a mechanism for combining sensor data from all sonar sensors which present different information. The FLC approach is achieved by means of Fuzzy Decision Making method type of fuzzy logic controller. The proposed controller is responsible for the obstacle avoidance of the mobile robot while traveling through a map from a home point to a goal point. The FLC is built as a subprogram based on the intelligent architecture (IA. The software program uses the Advanced Robotics Interface for Applications (ARIA, it is programmed with C++ package ( Visual C++.Net , and Networking software is used for setup Wireless TCP/IP Ethernet-to-Serial connection between robot and PC. The results show that the developed mobile robot travels successfully from one location to another and reaches its goal after avoiding all obstacles that are located in its way. The platform mobile robot is a Pioneer 3 DX that is equipped with Sonar sensors.

  18. Practical approach to apply range image sensors in machine automation (United States)

    Moring, Ilkka; Paakkari, Jussi


    In this paper we propose a practical approach to apply range imaging technology in machine automation. The applications we are especially interested in are industrial heavy-duty machines like paper roll manipulators in harbor terminals, harvesters in forests and drilling machines in mines. Characteristic of these applications is that the sensing system has to be fast, mid-ranging, compact, robust, and relatively cheap. On the other hand the sensing system is not required to be generic with respect to the complexity of scenes and objects or number of object classes. The key in our approach is that just a limited range data set or as we call it, a sparse range image is acquired and analyzed. This makes both the range image sensor and the range image analysis process more feasible and attractive. We believe that this is the way in which range imaging technology will enter the large industrial machine automation market. In the paper we analyze as a case example one of the applications mentioned and, based on that, we try to roughly specify the requirements for a range imaging based sensing system. The possibilities to implement the specified system are analyzed based on our own work on range image acquisition and interpretation.

  19. Modelling and numerical simulation of two-phase flows using the two-fluid two-pressure approach; Modelisation et simulation numerique des ecoulements diphasiques par une approche bifluide a deux pressions

    Energy Technology Data Exchange (ETDEWEB)

    Guillemaud, V


    This thesis is devoted to the modelling and numerical simulation of liquid-vapor flows. In order to describe these phase transition flows, a two-fluid two-pressure approach is considered. This description of the liquid-vapor mixing is associated to the seven-equation model introduced by Baer and Nunziato. This work investigates the properties of this model in order to simulate the phase transition flows occurring in nuclear engineering. First, a theoretical thermodynamic framework is constructed to describe the liquid-vapor mixing. Provided with this framework, various modelling choices are suggested for the interaction terms between the phases. These closure laws comply with an entropy inequality. The mathematical properties of this model are thereafter examined. The convective part is associated to a nonconservative hyperbolic system. First, we focus on the definition of its weak solutions. Several flow regimes for the two-phase mixing derive from this analysis. Such regimes for the two-phase flows are analogous to the torrential and fluvial regimes for the shallow-water equations. Furthermore, we establish the linear and nonlinear stabilities of the liquid-vapor equilibrium. Finally, the implementation of a turbulence model and the introduction of a reconstruction process for the interfacial area are investigated in order to refine the description of the interfacial transfers. Using a fractional step approach, a Finite Volume method is at last constructed to simulate this model. First, various nonconservative adaptations of standard Riemann solvers are developed to approach the convective part. Unlike the classic nonconservative framework, these schemes converge towards the same solution. Furthermore, a new relaxation scheme is proposed to approach the interfacial transfers. Provided with these schemes, the whole numerical method preserves the liquid-vapor equilibria. Using this numerical method, a careful comparison between the one- and two-pressure two

  20. Experimental approach and micro-mechanical modeling of the creep behavior of irradiated zirconium alloys; Approche experimentale et modelisation micromecanique du comportement en fluage des alliages de zircomium irradies

    Energy Technology Data Exchange (ETDEWEB)

    Ribis, J


    The fuel rod cladding, strongly affected by microstructural changes due to irradiation such as high density of dislocation loops, is strained by the end-of-life fuel rod internal pressure and the potential release of fission gases and helium during dry storage. Within the temperature range that is expected during dry interim storage, cladding undergoes long term creep under over-pressure. So, in order to have a predictive approach of the behavior of zirconium alloys cladding in dry storage conditions it is essential to take into account: initial dislocation loops, thermal annealing of loops and creep straining due to over pressure. Specific experiments and modelling for irradiated samples have been developed to improve our knowledge in that field. A Zr-1%Nb-O alloy was studied using fine microstructural investigations and mechanical testing. The observations conducted by transmission electron microscopy show that the high density of loops disappears during a heat treatment. The loop size becomes higher and higher while their density falls. The microhardness tests reveal that the fall of loop density leads to the softening of the irradiated material. During a creep test, both temperature and applied stress are responsible of the disappearance of loops. The loops could be swept by the activation of the basal slip system while the prism slip system is inhibited. Once deprived of loops, the creep properties of the irradiated materials are closed to the non irradiated state, a result whose consequence is a sudden acceleration of the creep rate. Finally, a micro-mechanical modeling based on microscopic deformation mechanisms taking into account experimental dislocation loop analyses and creep test, was used for a predictive approach by constructing a deformation mechanism map of the creep behavior of the irradiated material. (author)

  1. The resilience approach to climate adaptation applied for flood risk

    NARCIS (Netherlands)

    Gersonius, B.


    This dissertation presents a potential way forward for adaptation to climate change, termed the resilience approach. This approach takes a dynamic perspective on adaptive processes and the effects of these processes at/across different spatio-temporal scales. Experience is provided with four methods

  2. Continuous Molecular Fields Approach Applied to Structure-Activity Modeling

    CERN Document Server

    Baskin, Igor I


    The Method of Continuous Molecular Fields is a universal approach to predict various properties of chemical compounds, in which molecules are represented by means of continuous fields (such as electrostatic, steric, electron density functions, etc). The essence of the proposed approach consists in performing statistical analysis of functional molecular data by means of joint application of kernel machine learning methods and special kernels which compare molecules by computing overlap integrals of their molecular fields. This approach is an alternative to traditional methods of building 3D structure-activity and structure-property models based on the use of fixed sets of molecular descriptors. The methodology of the approach is described in this chapter, followed by its application to building regression 3D-QSAR models and conducting virtual screening based on one-class classification models. The main directions of the further development of this approach are outlined at the end of the chapter.

  3. Mechanical disequilibria in two-phase flow models: approaches by relaxation and by a reduced model; Modelisation des desequilibres mecaniques dans les ecoulements diphasiques: approches par relaxation et par modele reduit

    Energy Technology Data Exchange (ETDEWEB)

    Labois, M


    This thesis deals with hyperbolic models for the simulation of compressible two-phase flows, to find alternatives to the classical bi-fluid model. We first establish a hierarchy of two-phase flow models, obtained according to equilibrium hypothesis between the physical variables of each phase. The use of Chapman-Enskog expansions enables us to link the different existing models to each other. Moreover, models that take into account small physical unbalances are obtained by means of expansion to the order one. The second part of this thesis focuses on the simulation of flows featuring velocity unbalances and pressure balances, in two different ways. First, a two-velocity two-pressure model is used, where non-instantaneous velocity and pressure relaxations are applied so that a balancing of these variables is obtained. A new one-velocity one-pressure dissipative model is then proposed, where the arising of second-order terms enables us to take into account unbalances between the phase velocities. We develop a numerical method based on a fractional step approach for this model. (author)

  4. Beds Simulator 1.0: a software for the modelisation of the number of beds required for a hospital department. (United States)

    Nguyen, Jean-Michel; Six, Patrick; Antonioli, Daniel; Lombrail, Pierre; Le Beux, Pierre


    The determination of the number of beds needed for a hospital department is a complex problem that try to take into account efficiency, forecasting of needs, appropriateness of stays. Health authority used methods based on ratios that do not take into account local specificities and use rather to support an economic decision. On the other side, the models developed are too specific to be applied to all type of hospital department. Moreover, all the solutions depend on the LoS (Length of Stay). We have developed a non parametric method to solve this problem. This modelisation was successfully tested in teaching and non teaching hospitals, for an Intensive Care Unit, two Internal Medicine and a surgical departments. A software easy to use was developed, working on Windows available on our website

  5. Applying Digital Sensor Technology: A Problem-Solving Approach (United States)

    Seedhouse, Paul; Knight, Dawn


    There is currently an explosion in the number and range of new devices coming onto the technology market that use digital sensor technology to track aspects of human behaviour. In this article, we present and exemplify a three-stage model for the application of digital sensor technology in applied linguistics that we have developed, namely,…

  6. Laser therapy applying the differential approaches and biophotometrical elements (United States)

    Mamedova, F. M.; Akbarova, Ju. A.; Umarova, D. A.; Yudin, G. A.


    The aim of the present paper is the presentation of biophotometrical data obtained from various anatomic-topographical mouth areas to be used for the development of differential approaches to laser therapy in dentistry. Biophotometrical measurements were carried out using a portative biophotometer, as a portion of a multifunctional equipping system of laser therapy, acupuncture and biophotometry referred to as 'Aura-laser'. The results of biophotometrical measurements allow the implementation of differential approaches to laser therapy of parodontitis and mucous mouth tissue taking their clinic form and rate of disease into account.

  7. Dialogical Approach Applied in Group Counselling: Case Study (United States)

    Koivuluhta, Merja; Puhakka, Helena


    This study utilizes structured group counselling and a dialogical approach to develop a group counselling intervention for students beginning a computer science education. The study assesses the outcomes of group counselling from the standpoint of the development of the students' self-observation. The research indicates that group counselling…

  8. Conflicts, development and natural resources : An applied game theoretic approach

    NARCIS (Netherlands)

    Wick, A.K.


    This thesis also provides a critical view on a part of preceding resource curse results, namely the negative association between resources and economic performance. Arguing that the empirical literature on the topic up until now has ignored serious econometric concerns, a different approach is offer

  9. Applied Approaches of Rough Set Theory to Web Mining

    Institute of Scientific and Technical Information of China (English)

    SUN Tie-li; JIAO Wei-wei


    Rough set theory is a new soft computing tool, and has received much attention of researchers around the world. It can deal with incomplete and uncertain information. Now,it has been applied in many areas successfully. This paper introduces the basic concepts of rough set and discusses its applications in Web mining. In particular, some applications of rough set theory to intelligent information processing are emphasized.

  10. A Multi-Agent System Approach Applied to Light Raycasting

    Directory of Open Access Journals (Sweden)

    H. Andrade


    Full Text Available Light and shadows caused by the interaction with objects are important features in computer graphics which areusually taken into account to achieve realistic images. In order to simulate them, some attempts have been carried outwhich are based on direct illumination classical approaches as shadow mapping and shadow volumes. However,classical approaches in their beginnings could not support semi-transparent objects, soft-shadows, light interactionsinside objects and the possibility to update a scene based on previous information.In this paper a novel shadow casting approach is proposed to solve the previously mentioned problem using aninteractive cooperative multi agent system to provide a better understanding and easy customization of the renderedscenes; for instance, the scenes are represented with object agents that propagate rectilinear photon informationthrough them causing several changes on photon properties such as wavelength, intensity, among others. Thissystem uses a two-dimensional space represented by pixels.Our multi-agent system (MAS uses a blackboard architecture for storing and sharing data and the implicit invocationdesign pattern. The system was developed to calculate direct illumination in a two-dimensional space. In addition, theproposed system supports point light agents, opaque agents, semi-opaque agents and empty agents.A comparison is presented between the classic approaches and the proposed one presented in this work in scenescomposed of opaque and semi-opaque objects. The proposed approach, as opposed to the classical ones, allows theshadows to be casted by the light that passes through semi-opaque objects. The light is casted by one or many lightagents producing hard and soft shadows.

  11. Modular Modelling and Simulation Approach - Applied to Refrigeration Systems

    DEFF Research Database (Denmark)

    Sørensen, Kresten Kjær; Stoustrup, Jakob


    This paper presents an approach to modelling and simulation of the thermal dynamics of a refrigeration system, specifically a reefer container. A modular approach is used and the objective is to increase the speed and flexibility of the developed simulation environment. The refrigeration system...... is divided into components where the inputs and outputs are described by a set of XML files that can be combined into a composite system model that may be loaded into MATLABtrade. A set of tools that allows the user to easily load the model and run a simulation are provided. The results show a simulation...... speed-up of more than a factor of three by partitioning the model into smaller parts, and thereby isolating fast and slow dynamics. As a cost there is a reduction in accuracy which in the example considered is less than one percent....

  12. Applying a User-Centered Approach to Interactive Visualisation Design (United States)

    Wassink, Ingo; Kulyk, Olga; van Dijk, Betsy; van der Veer, Gerrit; van der Vet, Paul

    Analysing users in their context of work and finding out how and why they use different information resources is essential to provide interactive visualisation systems that match their goals and needs. Designers should actively involve the intended users throughout the whole process. This chapter presents a user-centered approach for the design of interactive visualisation systems. We describe three phases of the iterative visualisation design process: the early envisioning phase, the global specification phase, and the detailed specification phase. The whole design cycle is repeated until some criterion of success is reached. We discuss different techniques for the analysis of users, their tasks and domain. Subsequently, the design of prototypes and evaluation methods in visualisation practice are presented. Finally, we discuss the practical challenges in design and evaluation of collaborative visualisation environments. Our own case studies and those of others are used throughout the whole chapter to illustrate various approaches.

  13. A new kinetic biphasic approach applied to biodiesel process intensification

    Energy Technology Data Exchange (ETDEWEB)

    Russo, V.; Tesser, R.; Di Serio, M.; Santacesaria, E. [Naples Univ. (Italy). Dept. of Chemistry


    Many different papers have been published on the kinetics of the transesterification of vegetable oil with methanol, in the presence of alkaline catalysts to produce biodiesel. All the proposed approaches are based on the assumption of a pseudo-monophasic system. The consequence of these approaches is that some experimental aspects cannot be described. For the reaction performed in batch conditions, for example, the monophasic approach is not able to reproduce the different plateau obtained by using different amount of catalyst or the induction time observed at low stirring rates. Moreover, it has been observed by operating in continuous reactors that micromixing has a dramatic effect on the reaction rate. At this purpose, we have recently observed that is possible to obtain a complete conversion to biodiesel in less than 10 seconds of reaction time. This observation is confirmed also by other authors using different types of reactors like: static mixers, micro-reactors, oscillatory flow reactors, cavitational reactors, microwave reactors or centrifugal contactors. In this work we will show that a recently proposed biphasic kinetic approach is able to describe all the aspects before mentioned that cannot be described by the monophasic kinetic model. In particular, we will show that the biphasic kinetic model can describe both the induction time observed in the batch reactors, at low stirring rate, and the very high conversions obtainable in a micro-channel reactor. The adopted biphasic kinetic model is based on a reliable reaction mechanism that will be validated by the experimental evidences reported in this work. (orig.)

  14. Hamiltonian and Lagrangian Dynamical Matrix Approaches Applied to Magnetic Nanostructures

    Directory of Open Access Journals (Sweden)

    Roberto Zivieri


    Full Text Available Two micromagnetic tools to study the spin dynamics are reviewed. Both approaches are based upon the so-called dynamical matrix method, a hybrid micromagnetic framework used to investigate the spin-wave normal modes of confined magnetic systems. The approach which was formulated first is the Hamiltonian-based dynamical matrix method. This method, used to investigate dynamic magnetic properties of conservative systems, was originally developed for studying spin excitations in isolated magnetic nanoparticles and it has been recently generalized to study the dynamics of periodic magnetic nanoparticles. The other one, the Lagrangian-based dynamical matrix method, was formulated as an extension of the previous one in order to include also dissipative effects. Such dissipative phenomena are associated not only to intrinsic but also to extrinsic damping caused by injection of a spin current in the form of spin-transfer torque. This method is very accurate in identifying spin modes that become unstable under the action of a spin current. The analytical development of the system of the linearized equations of motion leads to a complex generalized Hermitian eigenvalue problem in the Hamiltonian dynamical matrix method and to a non-Hermitian one in the Lagrangian approach. In both cases, such systems have to be solved numerically.

  15. Applied Ethnobotany: Participatory Approach for Community Development and Conservation

    Institute of Scientific and Technical Information of China (English)


    Applied ethnobotany is a nev subject in ethnobiological sciences referring to the transferring, reviving and cultivating ethnobotanical knowledge among different social groups within intra-and-inter-communities. Much research related to biodiversity in many countries is largely devoted to the gathering of more academic information, rather than to more incise studies focusing on finding answers to pressing challenges related to the use of plants by communities. China is a country possessing rich biodiversity and cultural diversity. The long history of Chinese traditional medicine, diversity of cultivated crops and utilization of wild plant species are great cultural traditions to the country. Today, many societies of the country are still intricately linked to the natural environment economically as well as societies and groups within China. However, China is facing major changes in modernization of the country's economy, and globalization to form part of the world exchange system. Increasingly high levels of consumptions of natural plants, as well as national and international trades on plant products have resulted, space in over-harvesting of wild resources and accelerated environmental degradation. Local social structures and cultural traditions have also changed in order to cope with policy changes. In this background, over the last decade, applied ethnobotany for rural community development and conservation has been employed in different field projects and ethnic minority communities in Yunnan province of China. The applied ethnobotany has focused on work at community level to achieve sustainable use of natural resources and conservation. This presentation discusses findings and lessons learned from the projects on alternatives and innovations to shifting cultivation in Xishuangbanna, southwestern China.

  16. Benefits Approach to Leisure Applied to Sustainable Tourism Development

    Institute of Scientific and Technical Information of China (English)


    The Benefits Approach to Leisure (BAL), recognized as a major and badly needed "paradigm shift" in the way we conceive of and manage recreation resources, is believed to play a big role in achieving the sustainable development of tourism industry. BAL has been proved to be effective and efficient in the field of leisure and tourism in terms of its three types of benefits and two stages of production. This paper, using Aqua Zoo in Friesland, the Netherlands as a case, investigates the significance of BAL to ...

  17. Validation of models with constant bias: an applied approach

    Directory of Open Access Journals (Sweden)

    Salvador Medina-Peralta


    Full Text Available Objective. This paper presents extensions to the statistical validation method based on the procedure of Freese when a model shows constant bias (CB in its predictions and illustrate the method with data from a new mechanistic model that predict weight gain in cattle. Materials and methods. The extensions were the hypothesis tests and maximum anticipated error for the alternative approach, and the confidence interval for a quantile of the distribution of errors. Results. The model evaluated showed CB, once the CB is removed and with a confidence level of 95%, the magnitude of the error does not exceed 0.575 kg. Therefore, the validated model can be used to predict the daily weight gain of cattle, although it will require an adjustment in its structure based on the presence of CB to increase the accuracy of its forecasts. Conclusions. The confidence interval for the 1-α quantile of the distribution of errors after correcting the constant bias, allows determining the top limit for the magnitude of the error of prediction and use it to evaluate the evolution of the model in the forecasting of the system. The confidence interval approach to validate a model is more informative than the hypothesis tests for the same purpose.

  18. A Model-Based Prognostics Approach Applied to Pneumatic Valves (United States)

    Daigle, Matthew J.; Goebel, Kai


    Within the area of systems health management, the task of prognostics centers on predicting when components will fail. Model-based prognostics exploits domain knowledge of the system, its components, and how they fail by casting the underlying physical phenomena in a physics-based model that is derived from first principles. Uncertainty cannot be avoided in prediction, therefore, algorithms are employed that help in managing these uncertainties. The particle filtering algorithm has become a popular choice for model-based prognostics due to its wide applicability, ease of implementation, and support for uncertainty management. We develop a general model-based prognostics methodology within a robust probabilistic framework using particle filters. As a case study, we consider a pneumatic valve from the Space Shuttle cryogenic refueling system. We develop a detailed physics-based model of the pneumatic valve, and perform comprehensive simulation experiments to illustrate our prognostics approach and evaluate its effectiveness and robustness. The approach is demonstrated using historical pneumatic valve data from the refueling system.

  19. A Model-based Prognostics Approach Applied to Pneumatic Valves

    Directory of Open Access Journals (Sweden)

    Matthew J. Daigle


    Full Text Available Within the area of systems health management, the task of prognostics centers on predicting when components will fail. Model-based prognostics exploits domain knowledge of the system, its components, and how they fail by casting the underlying physical phenomena in a physics-based model that is derived from first principles. Uncertainty cannot be avoided in prediction, therefore, algorithms are employed that help in managing these uncertainties. The particle filtering algorithm has become a popular choice for model-based prognostics due to its wide applicability, ease of implementation, and support for uncertainty management. We develop a general model-based prognostics methodology within a robust probabilistic framework using particle filters. As a case study, we consider a pneumatic valve from the Space Shuttle cryogenic refueling system. We develop a detailed physics-based model of the pneumatic valve, and perform comprehensive simulation experiments to illustrate our prognostics approach and evaluate its effectiveness and robustness. The approach is demonstrated using historical pneumatic valve data from the refueling system.

  20. Modeling in applied sciences a kinetic theory approach

    CERN Document Server

    Pulvirenti, Mario


    Modeling complex biological, chemical, and physical systems, in the context of spatially heterogeneous mediums, is a challenging task for scientists and engineers using traditional methods of analysis Modeling in Applied Sciences is a comprehensive survey of modeling large systems using kinetic equations, and in particular the Boltzmann equation and its generalizations An interdisciplinary group of leading authorities carefully develop the foundations of kinetic models and discuss the connections and interactions between model theories, qualitative and computational analysis and real-world applications This book provides a thoroughly accessible and lucid overview of the different aspects, models, computations, and methodology for the kinetic-theory modeling process Topics and Features * Integrated modeling perspective utilized in all chapters * Fluid dynamics of reacting gases * Self-contained introduction to kinetic models * Becker–Doring equations * Nonlinear kinetic models with chemical reactions * Kinet...

  1. Fault Tolerant Robust Control Applied for Induction Motor (LMI approach

    Directory of Open Access Journals (Sweden)

    Hamouda KHECHINI


    Full Text Available This paper foregrounds fault tolerant robust control of uncertain dynamic linear systems in the state space representation. In fact, the industrial systems are more and more complex and the diagnosis process becomes indispensable to guarantee their surety of functioning and availability, that’s why a fault tolerant control law is imperative to achieve the diagnosis. In this paper, we address the problem of state feedback H2 /H∞ mixed with regional pole placement for linear continuous uncertain system. Sufficient conditions for feasibility are derived for a general class of convex regions of the complex plan. The conditions are presented as a collection of linear matrix inequalities (LMI 's. The efficiency and performance of this approach are then tested taking into consideration the robust control of a three- phase induction motor drive with the fluctuation of its parameters during the functioning.

  2. Applying artificial intelligence to clinical guidelines: the GLARE approach. (United States)

    Terenziani, Paolo; Montani, Stefania; Bottrighi, Alessio; Molino, Gianpaolo; Torchio, Mauro


    We present GLARE, a domain-independent system for acquiring, representing and executing clinical guidelines (GL). GLARE is characterized by the adoption of Artificial Intelligence (AI) techniques in the definition and implementation of the system. First of all, a high-level and user-friendly knowledge representation language has been designed. Second, a user-friendly acquisition tool, which provides expert physicians with various forms of help, has been implemented. Third, a tool for executing GL on a specific patient has been made available. At all the levels above, advanced AI techniques have been exploited, in order to enhance flexibility and user-friendliness and to provide decision support. Specifically, this chapter focuses on the methods we have developed in order to cope with (i) automatic resource-based adaptation of GL, (ii) representation and reasoning about temporal constraints in GL, (iii) decision making support, and (iv) model-based verification. We stress that, although we have devised such techniques within the GLARE project, they are mostly system-independent, so that they might be applied to other guideline management systems.

  3. Applying a cloud computing approach to storage architectures for spacecraft (United States)

    Baldor, Sue A.; Quiroz, Carlos; Wood, Paul

    As sensor technologies, processor speeds, and memory densities increase, spacecraft command, control, processing, and data storage systems have grown in complexity to take advantage of these improvements and expand the possible missions of spacecraft. Spacecraft systems engineers are increasingly looking for novel ways to address this growth in complexity and mitigate associated risks. Looking to conventional computing, many solutions have been executed to solve both the problem of complexity and heterogeneity in systems. In particular, the cloud-based paradigm provides a solution for distributing applications and storage capabilities across multiple platforms. In this paper, we propose utilizing a cloud-like architecture to provide a scalable mechanism for providing mass storage in spacecraft networks that can be reused on multiple spacecraft systems. By presenting a consistent interface to applications and devices that request data to be stored, complex systems designed by multiple organizations may be more readily integrated. Behind the abstraction, the cloud storage capability would manage wear-leveling, power consumption, and other attributes related to the physical memory devices, critical components in any mass storage solution for spacecraft. Our approach employs SpaceWire networks and SpaceWire-capable devices, although the concept could easily be extended to non-heterogeneous networks consisting of multiple spacecraft and potentially the ground segment.

  4. Introduction to semiconductor lasers for optical communications an applied approach

    CERN Document Server

    Klotzkin, David J


    This textbook provides a thorough and accessible treatment of semiconductor lasers from a design and engineering perspective. It includes both the physics of devices as well as the engineering, designing, and testing of practical lasers. The material is presented clearly with many examples provided. Readers of the book will come to understand the finer aspects of the theory, design, fabrication, and test of these devices and have an excellent background for further study of optoelectronics. This book also: ·         Provides a multi-faceted approach to explaining the theories behind semiconductor lasers, utilizing mathematical examples, illustrations, and written theoretical presentations ·         Offers a balance of relevant optoelectronic topics, with specific attention given to distributed feedback lasers, growth techniques, and waveguide cavity design ·         Provides a summary of every chapter, worked examples, and problems for readers to solve ·         Empasizes...

  5. Applying the community partnership approach to human biology research. (United States)

    Ravenscroft, Julia; Schell, Lawrence M; Cole, Tewentahawih'tha'


    Contemporary human biology research employs a unique skillset for biocultural analysis. This skillset is highly appropriate for the study of health disparities because disparities result from the interaction of social and biological factors over one or more generations. Health disparities research almost always involves disadvantaged communities owing to the relationship between social position and health in stratified societies. Successful research with disadvantaged communities involves a specific approach, the community partnership model, which creates a relationship beneficial for researcher and community. Paramount is the need for trust between partners. With trust established, partners share research goals, agree on research methods and produce results of interest and importance to all partners. Results are shared with the community as they are developed; community partners also provide input on analyses and interpretation of findings. This article describes a partnership-based, 20 year relationship between community members of the Akwesasne Mohawk Nation and researchers at the University at Albany. As with many communities facing health disparity issues, research with Native Americans and indigenous peoples generally is inherently politicized. For Akwesasne, the contamination of their lands and waters is an environmental justice issue in which the community has faced unequal exposure to, and harm by environmental toxicants. As human biologists engage in more partnership-type research, it is important to understand the long term goals of the community and what is at stake so the research circle can be closed and 'helicopter' style research avoided.

  6. Modelisation of Nitrification under Inhibited Environment by Moving Bed Bio-Film Reactor Technique

    Directory of Open Access Journals (Sweden)

    Pham T.H. Duc


    Full Text Available Problem statement: Nitrification by Moving Bed Biofilm Reactor (MBBR involves physical, chemical and biological processes to remove toxic ammonia for aquaculture that are governed by a variety of parameters, like substrate and dissolved oxygen concentrations, organic matters, temperature, pH, alkalinity and turbulence level, which impact negatively or positively on nitrification kinetics. Approach: The situation becomes more serious as the reaction rate is inhibited by low ammonium concentration and high salinity. That problems usually occur in treatment systems of aquatic breeding hatcheries. Results: In this study, experiments have been conducted to evaluate the impact of salinity on nitrification rate through kinetic constant (k and reaction order (n based on general equation v = kCn. Moving bed biofilm reactor was operated continuously at same initial amounts of nitrogen and Phosphorus very low (oligotrophic conditions. Firstly, over view the impact of salinity on kinetic rate to modeling that effect k and n to modelisation that affects and obtained the impact of salinity content in the reaction medium (X and the acclimatization phase (Y on the kinetic constant (k = 0.097 e (-0.0003Yƒ{0.0346X and on the kinetic order (n = (0.0002Y-0.0195 X-0.009Y + 1.2382. Conclusion/Recommendations: Results from kinetic analysis allowed the prediction of the reaction rate and reaction yield with rather high accuracy, helping the design and operation of a biofilter under practical conditions.

  7. Delayed Monocular SLAM Approach Applied to Unmanned Aerial Vehicles. (United States)

    Munguia, Rodrigo; Urzua, Sarquis; Grau, Antoni


    In recent years, many researchers have addressed the issue of making Unmanned Aerial Vehicles (UAVs) more and more autonomous. In this context, the state estimation of the vehicle position is a fundamental necessity for any application involving autonomy. However, the problem of position estimation could not be solved in some scenarios, even when a GPS signal is available, for instance, an application requiring performing precision manoeuvres in a complex environment. Therefore, some additional sensory information should be integrated into the system in order to improve accuracy and robustness. In this work, a novel vision-based simultaneous localization and mapping (SLAM) method with application to unmanned aerial vehicles is proposed. One of the contributions of this work is to design and develop a novel technique for estimating features depth which is based on a stochastic technique of triangulation. In the proposed method the camera is mounted over a servo-controlled gimbal that counteracts the changes in attitude of the quadcopter. Due to the above assumption, the overall problem is simplified and it is focused on the position estimation of the aerial vehicle. Also, the tracking process of visual features is made easier due to the stabilized video. Another contribution of this work is to demonstrate that the integration of very noisy GPS measurements into the system for an initial short period of time is enough to initialize the metric scale. The performance of this proposed method is validated by means of experiments with real data carried out in unstructured outdoor environments. A comparative study shows that, when compared with related methods, the proposed approach performs better in terms of accuracy and computational time.

  8. Numerical modelling in building thermo-aeraulics: from CFD modelling to an hybrid finite volume / zonal approach; Modelisation numerique de la thermoaeraulique du batiment: des modeles CFD a une approche hybride volumes finis / zonale

    Energy Technology Data Exchange (ETDEWEB)

    Bellivier, A.


    For 3D modelling of thermo-aeraulics in building using field codes, it is necessary to reduce the computing time in order to model increasingly larger volumes. The solution suggested in this study is to couple two modelling: a zonal approach and a CFD approach. The first part of the work that was carried out is the setting of a simplified CFD modelling. We propose rules for use of coarse grids, a constant effective viscosity law and adapted coefficients for heat exchange in the framework of building thermo-aeraulics. The second part of this work concerns the creation of fluid Macro-Elements and their coupling with a calculation of CFD finite volume type. Depending on the boundary conditions of the problem, a local description of the driving flow is proposed via the installation and use of semi-empirical evolution laws. The Macro-Elements is then inserted in CFD computation: the values of velocity calculated by the evolution laws are imposed on the CFD cells corresponding to the Macro-Element. We use these two approaches on five cases representative of thermo-aeraulics in buildings. The results are compared with experimental data and with traditional RANS simulations. We highlight the significant gain of time that our approach allows while preserving a good quality of numerical results. (author)

  9. Numerical modeling of the thermomechanical behavior of networks of underground galleries for the storage of the radioactive waste: approach by homogenization; Modelisation numerique du comportement thermomecanique de reseaux de galeries souterraines pour le stockage des dechets radioactifs: Approche par homogeneisation

    Energy Technology Data Exchange (ETDEWEB)

    Zokimila, P


    Deep geological disposal is one of the privileged options for the storage of High Level radioactive waste. A good knowledge of the behavior and properties of the potential geological formations as well as theirs evolution in time under the effect of the stress change induced by a possible installation of storage is required. The geological formation host will be subjected to mechanical and thermal solicitations due respectively to the excavation of the disposal tunnels and the release of heat of the canisters of radioactive waste. These thermomechanical solicitations will generate a stress relief in the host layer and disposal tunnels deformations as well as the extension of the damaged zones (EDZ) could cause local and global instabilities. This work aims to develop calculation methods to optimize numerical modeling of the thermoelastic behavior of the disposal at a large scale and to evaluate thermomechanical disturbance induced by storage on the geological formation host. Accordingly, after a presentation of the state of knowledge on the thermomechanical aspects of the rocks related to deep storage, of numerical modeling 2D and 3D of the thermoelastic behavior of individual disposal tunnel and a network of tunnels were carried out by a discrete approach. However, this classical approach is penalizing to study the global behavior of disposal storage. To mitigate that, an approach of numerical modeling, based on homogenization of periodic structures, was proposed. Formulations as numerical procedures were worked out to calculate the effective thermoelastic behavior of an equivalent heterogeneous structure. The model, obtained by this method, was validated with existing methods of homogenization such as the self-consistent model, as well as the Hashin-Shtrikman bounds. The comparison between the effective thermoelastic behavior and current thermoelastic behavior of reference showed a good coherence of the results. For an application to deep geological storage, the

  10. Quantitative characterization of initiation and propagation in stress corrosion cracking. An approach of a phenomenological model; Caracterisation quantitative de l`amorcage et de la propagation en corrosion sous contrainte. Approche d`une modelisation phenomenologique

    Energy Technology Data Exchange (ETDEWEB)

    Raquet, O.


    A purely phenomenological study of stress corrosion cracking was performed using the couple Z2CN 18.10 (304L) austenitic stainless steel/boiling MgCl{sub 2} aqueous solution. The exploitation of the morphological information (shape of the cracks and size distribution) available after constant elongation rate tests led to the proposal of an analytical expression of the crack initiation and growth rates. This representation allowed to quantitatively characterize the influence of the applied strain rate as well as the effect of corrosion inhibitors on the crack initiation and propagation phases. It can be used in the search for the stress corrosion cracking mechanisms as a `riddle` for the determination of the rate controlling steps. As a matter of fact, no mechanistic hypothesis has been used for its development. (author).

  11. Analysis of the institutional evaluation approach applied to the educational management of Costa Rica Christian School


    Campos Campos, Ana Jenssie


    The following article corresponds to the synthesis of a research work about the analysis of the Institutional Evaluation Approach applied to the educational management of a private school in the San José Norte Educational Region. The objectives of the analysis lied in identifying theinstitutional evaluation approach from the characteristics of the three approaches proposed, as well as on determining the dimensions of the approach used, and a third objective was determining the staff perceptio...

  12. A new multi criteria classification approach in a multi agent system applied to SEEG analysis. (United States)

    Kinié, A; Ndiaye, M; Montois, J J; Jacquelet, Y


    This work is focused on the study of the organization of the SEEG signals during epileptic seizures with multi-agent system approach. This approach is based on cooperative mechanisms of auto-organization at the micro level and of emergence of a global function at the macro level. In order to evaluate this approach we propose a distributed collaborative approach for the classification of the interesting signals. This new multi-criteria classification method is able to provide a relevant brain area structures organisation and to bring out epileptogenic networks elements. The method is compared to another classification approach a fuzzy classification and gives better results when applied to SEEG signals.

  13. Modelisation de l'historique d'operation de groupes turbine-alternateur (United States)

    Szczota, Mickael

    Because of their ageing fleet, the utility managers are increasingly in needs of tools that can help them to plan efficiently maintenance operations. Hydro-Quebec started a project that aim to foresee the degradation of their hydroelectric runner, and use that information to classify the generating unit. That classification will help to know which generating unit is more at risk to undergo a major failure. Cracks linked to the fatigue phenomenon are a predominant degradation mode and the loading sequences applied to the runner is a parameter impacting the crack growth. So, the aim of this memoir is to create a generator able to generate synthetic loading sequences that are statistically equivalent to the observed history. Those simulated sequences will be used as input in a life assessment model. At first, we describe how the generating units are operated by Hydro-Quebec and analyse the available data, the analysis shows that the data are non-stationnary. Then, we review modelisation and validation methods. In the following chapter a particular attention is given to a precise description of the validation and comparison procedure. Then, we present the comparison of three kind of model : Discrete Time Markov Chains, Discrete Time Semi-Markov Chains and the Moving Block Bootstrap. For the first two models, we describe how to take account for the non-stationnarity. Finally, we show that the Markov Chain is not adapted for our case, and that the Semi-Markov chains are better when they include the non-stationnarity. The final choice between Semi-Markov Chains and the Moving Block Bootstrap depends of the user. But, with a long term vision we recommend the use of Semi-Markov chains for their flexibility. Keywords: Stochastic models, Models validation, Reliability, Semi-Markov Chains, Markov Chains, Bootstrap

  14. Chemical, spectroscopic, and ab initio modelling approach to interfacial reactivity applied to anion retention by siderite; Approche couplee chimique, spectroscopique et de modelisation ab initio a la reactivite de surface: application a la retention des anions par la siderite

    Energy Technology Data Exchange (ETDEWEB)

    Badaut, V.


    Among the many radionuclides contained in high-level nuclear waste, {sup 79}Se was identified as a potential threat to the safety of long term underground storage. However, siderite (FeCO{sub 3}) is known to form upon corrosion of the waste container, and the impact of this mineral on the fate of selenium was not accounted for. In this work, the interactions between selenium oxyanions - selenate and selenite - and siderite were investigated. To this end, both experimental characterizations (solution chemistry, X-ray Absorption Spectroscopy - XAS) and theoretical studies (ab initio modelling using Density Functional Theory - DFT) were performed. Selenite and selenate ({<=} 10{sup 3} M) retention experiments by siderite suspensions (75 g/L) at neutral pH in reducing glovebox (5 % H{sub 2}) showed that selenite is quantitatively immobilized by siderite after 48 h of reaction time, when selenate is only partly immobilized after 10 days. In the selenite case, XAS showed that immobilized selenium is initially present as Se(IV) probably sorbed on siderite surface. After 10 days of reaction, selenite ions are quantitatively reduced and form poorly crystalline elementary selenium. Selenite retention and reduction kinetics are therefore distinct. On the other hand, the fraction of immobilized selenate retained in the solid fraction does not appear to be significantly reduced over the probed timescale (10 days). For a better understanding of the reduction mechanism of selenite ions by siderite, the properties of bulk and perfect surfaces of siderite were modelled using DFT. We suggest that the properties of the valence electrons can be correctly described only if the symmetry of the fundamental state electronic density is lower than the experimental crystallographic symmetry. We then show that the retention of simple molecules as O{sub 2} or H{sub 2}O on siderite and magnesite (10{sup -14}) perfect surfaces (perfect cleavage plane, whose surface energy is the lowest according to DFT) can be modelled with good agreement with the literature. Finally, the modelling of selenite surface complexes on magnesite is performed with and without hydration. These results confirm that selenite should be quantitatively reduced as elementary selenium in presence of siderite, and therefore should not contribute to the overall radiotoxicity of the storage. On the contrary, selenate is seems not to be significantly immobilized nor reduced in presence of siderite. (author)

  15. Seismic rupture modelling, strong motion prediction and seismic hazard assessment: fundamental and applied approaches; Modelisation de la rupture sismique, prediction du mouvement fort, et evaluation de l'alea sismique: approches fondamentale et appliquee

    Energy Technology Data Exchange (ETDEWEB)

    Berge-Thierry, C


    The defence to obtain the 'Habilitation a Diriger des Recherches' is a synthesis of the research work performed since the end of my Ph D. thesis in 1997. This synthesis covers the two years as post doctoral researcher at the Bureau d'Evaluation des Risques Sismiques at the Institut de Protection (BERSSIN), and the seven consecutive years as seismologist and head of the BERSSIN team. This work and the research project are presented in the framework of the seismic risk topic, and particularly with respect to the seismic hazard assessment. Seismic risk combines seismic hazard and vulnerability. Vulnerability combines the strength of building structures and the human and economical consequences in case of structural failure. Seismic hazard is usually defined in terms of plausible seismic motion (soil acceleration or velocity) in a site for a given time period. Either for the regulatory context or the structural specificity (conventional structure or high risk construction), seismic hazard assessment needs: to identify and locate the seismic sources (zones or faults), to characterize their activity, to evaluate the seismic motion to which the structure has to resist (including the site effects). I specialized in the field of numerical strong-motion prediction using high frequency seismic sources modelling and forming part of the IRSN allowed me to rapidly working on the different tasks of seismic hazard assessment. Thanks to the expertise practice and the participation to the regulation evolution (nuclear power plants, conventional and chemical structures), I have been able to work on empirical strong-motion prediction, including site effects. Specific questions related to the interface between seismologists and structural engineers are also presented, especially the quantification of uncertainties. This is part of the research work initiated to improve the selection of the input ground motion in designing or verifying the stability of structures. (author)

  16. Metrology Influence on the Cutting Modelisation

    CERN Document Server

    Cahuc, Olivier


    High speed machining has been improved thanks to considerable advancement on the tools (optimum geometry, harder materials), on machined materials (increased workability and machining capacity for harder workpieces) and finally on the machines (higher accuracy and power at the high speeds, performances of the numerical control system). However at such loading velocities, the cutting process generates high strain and high-speed strain which cause complex, various and irreversible phenomena in plasticity. These phenomena are comprehended through the complete measurement of the mechanical actions using a six-component dynamometer and flux and temperatures measurements at the tip of the cutting tool. Balanced energy assessments are the starting points of our reflection on the machining modelling. The modelling of these phenomena and the material behaviour under this type of loading requires a suitable theoretical approach. The main points of the strain gradient theory are developed. A theoretical behaviour law ad...

  17. A Geometric Approach to Diagnosis Applied to A Ship Propulsion Problem

    DEFF Research Database (Denmark)

    Lootsma, T.F.; Izadi-Zamanabadi, Roozbeh; Nijmeijer, H.

    A geometric approach to FDI diagnosis for input-affine nonlinear systems is briefly described and applied to a ship propulsion benchmark. The analysis method is used to examine the possibility of detecting and isolating predefined faults in the system. The considered faults cover sensor, actuator...

  18. Geothermal potential assessment for a low carbon strategy : A new systematic approach applied in southern Italy

    NARCIS (Netherlands)

    Trumpy, E.; Botteghi, S.; Caiozzi, F.; Donato, A.; Gola, G.; Montanari, D.; Pluymaekers, M. P D; Santilano, A.; van Wees, J. D.; Manzella, A.


    In this study a new approach to geothermal potential assessment was set up and applied in four regions in southern Italy. Our procedure, VIGORThermoGIS, relies on the volume method of assessment and uses a 3D model of the subsurface to integrate thermal, geological and petro-physical data. The metho

  19. Uncharted territory: A complex systems approach as an emerging paradigm in applied linguistics

    Directory of Open Access Journals (Sweden)

    Albert J Weideman


    Full Text Available Developing a theory of applied linguistics is a top priority for the discipline today. The emergence of a new paradigm - a complex systems approach - in applied linguistics presents us with a unique opportunity to give prominence to the development of a foundational framework for this design discipline. Far from being a mere philosophical exercise, such a framework will find application in the training and induction of new entrants into the discipline within the developing context of South Africa, as well as internationally.

  20. A generalised chemical precipitation modelling approach in wastewater treatment applied to calcite

    DEFF Research Database (Denmark)

    Mbamba, Christian Kazadi; Batstone, Damien J.; Flores Alsina, Xavier


    , the present study aims to identify a broadly applicable precipitation modelling approach. The study uses two experimental platforms applied to calcite precipitating from synthetic aqueous solutions to identify and validate the model approach. Firstly, dynamic pH titration tests are performed to define...... of the mineral particulate state (Xcryst) and, for calcite, have a 2nd order dependency (exponent n ¼ 2.05 ± 0.29) on thermodynamic supersaturation (s). Parameter analysis indicated that the model was more tolerant to a fast kinetic coefficient (kcryst) and so, in general, it is recommended that a large kcryst...

  1. Challenges and Limitations of Applying an Emotion-driven Design Approach on Elderly Users

    DEFF Research Database (Denmark)

    Andersen, Casper L.; Gudmundsson, Hjalte P.; Achiche, Sofiane


    a competitive advantage for companies. In this paper, challenges of applying an emotion-driven design approach applied on elderly people, in order to identify their user needs towards walking frames, are discussed. The discussion will be based on the experiences and results obtained from the case study....... To measure the emotional responses of the elderly, a questionnaire was designed and adapted from P.M.A. Desmet’s product-emotion measurement instrument: PrEmo. During the case study it was observed that there were several challenges when carrying out the user survey, and that those challenges particularly...... related to the participants’ age and cognitive abilities. The challenges encountered are discussed and guidelines on what should be taken into account to facilitate an emotion-driven design approach for elderly people are proposed....

  2. Social media marketing analytics : a multicultural approach applied to the beauty \\& cosmetic sector


    Kefi, Hajer; Indra, Sitesh; Abdessalem, Talel


    We present in this paper a multicultural approach to social media marketing analytics, applied in two Facebook brand pages: French (individualistic culture, the country home of the brand) versus Saudi Arabian (collectivistic culture, one of its country hosts), which are published by an internationalbeauty \\& cosmetics firm. Using social network analysis and content analysis, we identify the most popular posts and the most influential users within these two brand pages and highlight the differ...

  3. Assessing switchability for biosimilar products: modelling approaches applied to children's growth. (United States)

    Belleli, Rossella; Fisch, Roland; Renard, Didier; Woehling, Heike; Gsteiger, Sandro


    The present paper describes two statistical modelling approaches that have been developed to demonstrate switchability from the original recombinant human growth hormone (rhGH) formulation (Genotropin(®) ) to a biosimilar product (Omnitrope(®) ) in children suffering from growth hormone deficiency. Demonstrating switchability between rhGH products is challenging because the process of growth varies with the age of the child and across children. The first modelling approach aims at predicting individual height measured at several time-points after switching to the biosimilar. The second modelling approach provides an estimate of the deviation from the overall growth rate after switching to the biosimilar, which can be regarded as an estimate of switchability. The results after applying these approaches to data from a randomized clinical trial are presented. The accuracy and precision of the predictions made using the first approach and the small deviation from switchability estimated with the second approach provide sufficient evidence to conclude that switching from Genotropin(®) to Omnitrope(®) has a very small effect on growth, which is neither statistically significant nor clinically relevant.

  4. An approach of optimal sensitivity applied in the tertiary loop of the automatic generation control

    Energy Technology Data Exchange (ETDEWEB)

    Belati, Edmarcio A. [CIMATEC - SENAI, Salvador, BA (Brazil); Alves, Dilson A. [Electrical Engineering Department, FEIS, UNESP - Sao Paulo State University (Brazil); da Costa, Geraldo R.M. [Electrical Engineering Department, EESC, USP - Sao Paulo University (Brazil)


    This paper proposes an approach of optimal sensitivity applied in the tertiary loop of the automatic generation control. The approach is based on the theorem of non-linear perturbation. From an optimal operation point obtained by an optimal power flow a new optimal operation point is directly determined after a perturbation, i.e., without the necessity of an iterative process. This new optimal operation point satisfies the constraints of the problem for small perturbation in the loads. The participation factors and the voltage set point of the automatic voltage regulators (AVR) of the generators are determined by the technique of optimal sensitivity, considering the effects of the active power losses minimization and the network constraints. The participation factors and voltage set point of the generators are supplied directly to a computational program of dynamic simulation of the automatic generation control, named by power sensitivity mode. Test results are presented to show the good performance of this approach. (author)

  5. Responses of mink to auditory stimuli: Prerequisites for applying the ‘cognitive bias’ approach

    DEFF Research Database (Denmark)

    Svendsen, Pernille Maj; Malmkvist, Jens; Halekoh, Ulrich


    The aim of the study was to determine and validate prerequisites for applying a cognitive (judgement) bias approach to assessing welfare in farmed mink (Neovison vison). We investigated discrimination ability and associative learning ability using auditory cues. The mink (n = 15 females) were...... mink only showed habituation in experiment 2. Regardless of the frequency used (2 and 18 kHz), cues predicting the danger situation initially elicited slower responses compared to those predicting the safe situation but quickly became faster. Using auditory cues as discrimination stimuli for female...... farmed mink in a judgement bias approach would thus appear to be feasible. However several specific issues are to be considered in order to successfully adapt a cognitive bias approach to mink, and these are discussed....

  6. Addressing dependability by applying an approach for model-based risk assessment

    Energy Technology Data Exchange (ETDEWEB)

    Gran, Bjorn Axel [Institutt for energiteknikk, OECD Halden Reactor Project, NO-1751 Halden (Norway)]. E-mail:; Fredriksen, Rune [Institutt for energiteknikk, OECD Halden Reactor Project, NO-1751 Halden (Norway)]. E-mail:; Thunem, Atoosa P.-J. [Institutt for energiteknikk, OECD Halden Reactor Project, NO-1751 Halden (Norway)]. E-mail:


    This paper describes how an approach for model-based risk assessment (MBRA) can be applied for addressing different dependability factors in a critical application. Dependability factors, such as availability, reliability, safety and security, are important when assessing the dependability degree of total systems involving digital instrumentation and control (I and C) sub-systems. In order to identify risk sources their roles with regard to intentional system aspects such as system functions, component behaviours and intercommunications must be clarified. Traditional risk assessment is based on fault or risk models of the system. In contrast to this, MBRA utilizes success-oriented models describing all intended system aspects, including functional, operational and organizational aspects of the target. The EU-funded CORAS project developed a tool-supported methodology for the application of MBRA in security-critical systems. The methodology has been tried out within the telemedicine and e-commerce areas, and provided through a series of seven trials a sound basis for risk assessments. In this paper the results from the CORAS project are presented, and it is discussed how the approach for applying MBRA meets the needs of a risk-informed Man-Technology-Organization (MTO) model, and how methodology can be applied as a part of a trust case development.

  7. Solution of the neutron point kinetics equations with temperature feedback effects applying the polynomial approach method

    Energy Technology Data Exchange (ETDEWEB)

    Tumelero, Fernanda, E-mail: [Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS (Brazil). Programa de Pos-Graduacao em Engenharia Mecanica; Petersen, Claudio Z.; Goncalves, Glenio A.; Lazzari, Luana, E-mail:, E-mail:, E-mail: [Universidade Federal de Pelotas (DME/UFPEL), Capao do Leao, RS (Brazil). Instituto de Fisica e Matematica


    In this work, we present a solution of the Neutron Point Kinetics Equations with temperature feedback effects applying the Polynomial Approach Method. For the solution, we consider one and six groups of delayed neutrons precursors with temperature feedback effects and constant reactivity. The main idea is to expand the neutron density, delayed neutron precursors and temperature as a power series considering the reactivity as an arbitrary function of the time in a relatively short time interval around an ordinary point. In the first interval one applies the initial conditions of the problem and the analytical continuation is used to determine the solutions of the next intervals. With the application of the Polynomial Approximation Method it is possible to overcome the stiffness problem of the equations. In such a way, one varies the time step size of the Polynomial Approach Method and performs an analysis about the precision and computational time. Moreover, we compare the method with different types of approaches (linear, quadratic and cubic) of the power series. The answer of neutron density and temperature obtained by numerical simulations with linear approximation are compared with results in the literature. (author)

  8. Modeling of acoustic wave propagation and scattering for telemetry of complex structures; Modelisation de la propagation et de l'interaction d'une onde acoustique pour la telemetrie de structures complexes

    Energy Technology Data Exchange (ETDEWEB)

    LU, B.


    This study takes place in the framework of tools development for the telemetry simulation. Telemetry is a possible technology applied to monitoring the sodium-cooled fast reactors (SFR) and consists in positioning in the reactor core a transducer to generate an ultrasonic beam. This beam propagates through an inhomogeneous random medium since temperature fluctuations occur in the liquid sodium and consequently the sound velocity fluctuates as well, which modifies the bream propagation. Then the beam interacts with a reactor structure immersed in sodium. By measuring the time of flight of the backscattered echo received by the same transducer, one can determine the precise location of the structure. The telemetry simulation therefore requires modeling of both the acoustic wave propagation in an inhomogeneous random medium and the interaction of this wave with structures of various shapes; this is the objective of this work. A stochastic model based on a Monte Carlo algorithm is developed in order to take into account the random fluctuations of the acoustic field. The acoustic field through an inhomogeneous random medium is finally modeled from the field calculated in a mean homogeneous medium by modifying the travel times of rays in the homogeneous medium, using a correction provided by the stochastic model. This stochastic propagation model has been validated by comparison with a deterministic model and is much simpler to integrate in the CIVA software platform for non destructive evaluation simulation and less time consuming than the deterministic model. In order to model the interaction between the acoustic wave and the immersed structures, classical diffraction models have been evaluated for rigid structures, including the geometrical theory of diffraction (GTD) and the Kirchhoff approximation (KA). These two approaches appear to be complementary. Combining them so as to retain only their advantages, we have developed a hybrid model (the so-called refined KA

  9. Learning About Dying and Living: An Applied Approach to End-of-Life Communication. (United States)

    Pagano, Michael P


    The purpose of this article is to expand on prior research in end-of-life communication and death and dying communication apprehension, by developing a unique course that utilizes a hospice setting and an applied, service-learning approach. Therefore, this essay describes and discusses both students' and my experiences over a 7-year period from 2008 through 2014. The courses taught during this time frame provided an opportunity to analyze students' responses, experiences, and discoveries across semesters/years and cocultures. This unique, 3-credit, 14-week, service-learning, end-of-life communication course was developed to provide an opportunity for students to learn the theories related to this field of study and to apply that knowledge through volunteer experiences via interactions with dying patients and their families. The 7 years of author's notes, plus the 91 students' electronically submitted three reflection essays each (273 total documents) across four courses/years, served as the data for this study. According to the students, verbally in class discussions and in numerous writing assignments, this course helped lower their death and dying communication apprehension and increased their willingness to interact with hospice patients and their families. Furthermore, the students' final research papers clearly demonstrated how utilizing a service-learning approach allowed them to apply classroom learnings and interactions with dying patients and their families at the hospice, to their analyses of end-of-life communication theories and behaviors. The results of these classes suggest that other, difficult topic courses (e.g., domestic violence, addiction, etc.) might benefit from a similar pedagogical approach.

  10. Applying the health action process approach (HAPA) to the choice of health products: An exploratory study

    DEFF Research Database (Denmark)

    Krutulyte, Rasa; Grunert, Klaus G.; Scholderer, Joachim;

    on the role of the behavioural intention predictors such as risk perception, outcome expectations and self-efficacy. The model has been proved to be a useful framework for understanding consumer choosing health food and is substantial in the further application of dietary choice issues.......This paper presents the results of a qualitative pilot study that aimed to uncovering Danish consumers' motives for choosing health food. Schwarzer's (1992) health action process approach (HAPA) was applied to understand the process by which people chose health products. The research focused...

  11. Applying a learning design methodology in the flipped classroom approach – empowering teachers to reflect

    DEFF Research Database (Denmark)

    Triantafyllou, Evangelia; Kofoed, Lise; Purwins, Hendrik


    , while class time is devoted to clarifications and application of this knowledge. The hypothesis is that there could be deep and creative discussions when teacher and students physically meet. This paper discusses how the learning design methodology can be applied to represent, share and guide educators......One of the recent developments in teaching that heavily relies on current technology is the “flipped classroom” approach. In a flipped classroom the traditional lecture and homework sessions are inverted. Students are provided with online material in order to gain necessary knowledge before class...... through flipped classroom designs. In order to discuss the opportunities arising by this approach, the different components of the Learning Design – Conceptual Map (LD-CM) are presented and examined in the context of the flipped classroom. It is shown that viewing the flipped classroom through the lens...

  12. Finite strain response of crimped fibers under uniaxial traction: An analytical approach applied to collagen (United States)

    Marino, Michele; Wriggers, Peter


    Composite materials reinforced by crimped fibers intervene in a number of advanced structural applications. Accordingly, constitutive equations describing their anisotropic behavior and explicitly accounting for fiber properties are needed for modeling and design purposes. To this aim, the finite strain response of crimped beams under uniaxial traction is herein addressed by obtaining analytical relationships based on the Principle of Virtual Works. The model is applied to collagen fibers in soft biological tissues, coupling geometric nonlinearities related to fiber crimp with material nonlinearities due to nanoscale mechanisms. Several numerical applications are presented, addressing the influence of geometric and material features. Available experimental data for tendons are reproduced, integrating the proposed approach within an optimization procedure for data fitting. The obtained results highlight the effectiveness of the proposed approach in correlating fibers structure with composite material mechanics.

  13. Pilot-testing an applied competency-based approach to health human resources planning. (United States)

    Tomblin Murphy, Gail; MacKenzie, Adrian; Alder, Rob; Langley, Joanne; Hickey, Marjorie; Cook, Amanda


    A competency-based approach to health human resources (HHR) planning is one that explicitly considers the spectrum of knowledge, skills and judgement (competencies) required for the health workforce based on the health needs of the relevant population in some specific circumstances. Such an approach is of particular benefit to planners challenged to make optimal use of limited HHR as it allows them to move beyond simply estimating numbers of certain professionals required and plan instead according to the unique mix of competencies available from the existing health workforce. This kind of flexibility is particularly valuable in contexts where healthcare providers are in short supply generally (e.g. in many developing countries) or temporarily due to a surge in need (e.g. a pandemic or other disease outbreak). A pilot application of this approach using the context of an influenza pandemic in one health district of Nova Scotia, Canada, is described, and key competency gaps identified. The approach is also being applied using other conditions in other Canadian jurisdictions and in Zambia.

  14. New aspects of developing a dry powder inhalation formulation applying the quality-by-design approach. (United States)

    Pallagi, Edina; Karimi, Keyhaneh; Ambrus, Rita; Szabó-Révész, Piroska; Csóka, Ildikó


    The current work outlines the application of an up-to-date and regulatory-based pharmaceutical quality management method, applied as a new development concept in the process of formulating dry powder inhalation systems (DPIs). According to the Quality by Design (QbD) methodology and Risk Assessment (RA) thinking, a mannitol based co-spray dried formula was produced as a model dosage form with meloxicam as the model active agent. The concept and the elements of the QbD approach (regarding its systemic, scientific, risk-based, holistic, and proactive nature with defined steps for pharmaceutical development), as well as the experimental drug formulation (including the technological parameters assessed and the methods and processes applied) are described in the current paper. Findings of the QbD based theoretical prediction and the results of the experimental development are compared and presented. Characteristics of the developed end-product were in correlation with the predictions, and all data were confirmed by the relevant results of the in vitro investigations. These results support the importance of using the QbD approach in new drug formulation, and prove its good usability in the early development process of DPIs. This innovative formulation technology and product appear to have a great potential in pulmonary drug delivery.

  15. A novel optical calorimetry dosimetry approach applied to an HDR Brachytherapy source (United States)

    Cavan, A.; Meyer, J.


    The technique of Digital Holographic Interferometry (DHI) is applied to the measurement of radiation absorbed dose distribution in water. An optical interferometer has been developed that captures the small variations in the refractive index of water due to the radiation induced temperature increase ΔT. The absorbed dose D is then determined with high temporal and spatial resolution using the calorimetric relation D=cΔT (where c is the specific heat capacity of water). The method is capable of time resolving 3D spatial calorimetry. As a proof-of-principle of the approach, a prototype DHI dosimeter was applied to the measurement of absorbed dose from a High Dose Rate (HDR) Brachytherapy source. Initial results are in agreement with modelled doses from the Brachyvision treatment planning system, demonstrating the viability of the system for high dose rate applications. Future work will focus on applying corrections for heat diffusion and geometric effects. The method has potential to contribute to the dosimetry of diverse high dose rate applications which require high spatial resolution such as microbeam radiotherapy (MRT) or small field proton beam dosimetry but may potentially also be useful for interface dosimetry.

  16. The active analog approach applied to the pharmacophore identification of benzodiazepine receptor ligands (United States)

    Tebib, Souhail; Bourguignon, Jean-Jacques; Wermuth, Camille-Georges


    Applied to seven potent benzodiazepine-receptor ligands belonging to chemically different classes, the active analog approach allowed the stepwise identification of the pharmacophoric pattern associated with the recognition by the benzodiazepine receptor. A unique pharmacophore model was derived which involves six critical zones: (a) a π-electron rich aromatic (PAR) zone; (b) two electron-rich zones δ1 and δ2 placed at 5.0 and 4.5 Å respectively from the reference centroid in the PAR zone; (c) a freely rotating aromatic ring (FRA) region; (d) an out-of-plane region (OPR), strongly associated with agonist properties; and (e) an additional hydrophobic region (AHR). The model accommodates all presently known ligands of the benzodiazepine receptor, identifies sensitivity to steric hindrance close to the δ1 zone, accounts for R and S differential affinities and distinguishes requirements for agonist versus non-agonist activity profiles.

  17. An extended master-equation approach applied to aggregation in freeway traffic

    Institute of Scientific and Technical Information of China (English)

    Li Jun-Wei; Lin Bo-Liang; Huang Yong-Chang


    We restudy the master-equation approach applied to aggregation in a one-dimensional freeway,where the decay transition probabilities for the jump processes are reconstructed based on a car-following model. According to the reconstructed transition probabilities,the clustering behaviours and the stochastic properties of the master equation in a one-lane freeway traffic model are investigated in detail.The numerical results show that the size of the clusters initially below the critical size of the unstable cluster and initially above that of the unstable cluster all enter the same stable state,which also accords with the nucleation theory and is known from the result in earlier work.Moreover,we have obtained more reasonable parameters of the master equation based on some results of cellular automata models.

  18. Software engineering techniques applied to agricultural systems an object-oriented and UML approach

    CERN Document Server

    Papajorgji, Petraq J


    Software Engineering Techniques Applied to Agricultural Systems presents cutting-edge software engineering techniques for designing and implementing better agricultural software systems based on the object-oriented paradigm and the Unified Modeling Language (UML). The focus is on the presentation of  rigorous step-by-step approaches for modeling flexible agricultural and environmental systems, starting with a conceptual diagram representing elements of the system and their relationships. Furthermore, diagrams such as sequential and collaboration diagrams are used to explain the dynamic and static aspects of the software system.    This second edition includes: a new chapter on Object Constraint Language (OCL), a new section dedicated to the Model-VIEW-Controller (MVC) design pattern, new chapters presenting details of two MDA-based tools – the Virtual Enterprise and Olivia Nova, and a new chapter with exercises on conceptual modeling.  It may be highly useful to undergraduate and graduate students as t...

  19. Positive Mathematical Programming Approaches – Recent Developments in Literature and Applied Modelling

    Directory of Open Access Journals (Sweden)

    Thomas Heckelei


    Full Text Available This paper reviews and discusses the more recent literature and application of Positive Mathematical Programming in the context of agricultural supply models. Specifically, advances in the empirical foundation of parameter specifications as well as the economic rationalisation of PMP models – both criticized in earlier reviews – are investigated. Moreover, the paper provides an overview on a larger set of models with regular/repeated policy application that apply variants of PMP. Results show that most applications today avoid arbitrary parameter specifications and rely on exogenous information on supply responses to calibrate model parameters. However, only few approaches use multiple observations to estimate parameters, which is likely due to the still considerable technical challenges associated with it. Equally, we found only limited reflection on the behavioral or technological assumptions that could rationalise the PMP model structure while still keeping the model’s advantages.

  20. Operative terminology and post-operative management approaches applied to hepatic surgery: Trainee perspectives. (United States)

    Farid, Shahid G; Prasad, K Rajendra; Morris-Stiff, Gareth


    Outcomes in hepatic resectional surgery (HRS) have improved as a result of advances in the understanding of hepatic anatomy, improved surgical techniques, and enhanced peri-operative management. Patients are generally cared for in specialist higher-level ward settings with multidisciplinary input during the initial post-operative period, however, greater acceptance and understanding of HRS has meant that care is transferred, usually after 24-48 h, to a standard ward environment. Surgical trainees will be presented with such patients either electively as part of a hepatobiliary firm or whilst covering the service on-call, and it is therefore important to acknowledge the key points in managing HRS patients. Understanding the applied anatomy of the liver is the key to determining the extent of resection to be undertaken. Increasingly, enhanced patient pathways exist in the post-operative setting requiring focus on the delivery of high quality analgesia, careful fluid balance, nutrition and thromboprophlaxis. Complications can occur including liver, renal and respiratory failure, hemorrhage, and sepsis, all of which require prompt recognition and management. We provide an overview of the relevant terminology applied to hepatic surgery, an approach to the post-operative management, and an aid to developing an awareness of complications so as to facilitate better confidence in this complex subgroup of general surgical patients.

  1. Mathematic simulation of soil-vegetation condition and land use structure applying basin approach (United States)

    Mishchenko, Natalia; Shirkin, Leonid; Krasnoshchekov, Alexey


    Ecosystems anthropogenic transformation is basically connected to the changes of land use structure and human impact on soil fertility. The Research objective is to simulate the stationary state of river basins ecosystems. Materials and Methods. Basin approach has been applied in the research. Small rivers basins of the Klyazma river have been chosen as our research objects. They are situated in the central part of the Russian plain. The analysis is carried out applying integrated characteristics of ecosystems functioning and mathematic simulation methods. To design mathematic simulator functional simulation methods and principles on the basis of regression, correlation and factor analysis have been applied in the research. Results. Mathematic simulation resulted in defining possible permanent conditions of "phytocenosis-soil" system in coordinates of phytomass, phytoproductivity, humus percentage in soil. Ecosystem productivity is determined not only by vegetation photosynthesis activity but also by the area ratio of forest and meadow phytocenosis. Local maximums attached to certain phytomass areas and humus content in soil have been defined on the basin phytoproductivity distribution diagram. We explain the local maximum by synergetic effect. It appears with the definite ratio of forest and meadow phytocenosis. In this case, utmost values of phytomass for the whole area are higher than just a sum of utmost values of phytomass for the forest and meadow phytocenosis. Efficient correlation of natural forest and meadow phytocenosis has been defined for the Klyazma river. Conclusion. Mathematic simulation methods assist in forecasting the ecosystem conditions under various changes of land use structure. Nowadays overgrowing of the abandoned agricultural lands is very actual for the Russian Federation. Simulation results demonstrate that natural ratio of forest and meadow phytocenosis for the area will restore during agricultural overgrowing.

  2. Distribution function approach to redshift space distortions. Part IV: perturbation theory applied to dark matter

    CERN Document Server

    Vlah, Zvonimir; McDonald, Patrick; Okumura, Teppei; Baldauf, Tobias


    We develop a perturbative approach to redshift space distortions (RSD) using the phase space distribution function approach and apply it to the dark matter redshift space power spectrum and its moments. RSD can be written as a sum over density weighted velocity moments correlators, with the lowest order being density, momentum density and stress energy density. We use standard and extended perturbation theory (PT) to determine their auto and cross correlators, comparing them to N-body simulations. We show which of the terms can be modeled well with the standard PT and which need additional terms that include higher order corrections which cannot be modeled in PT. Most of these additional terms are related to the small scale velocity dispersion effects, the so called finger of god (FoG) effects, which affect some, but not all, of the terms in this expansion, and which can be approximately modeled using a simple physically motivated ansatz such as the halo model. We point out that there are several velocity dis...

  3. A multi-label, semi-supervised classification approach applied to personality prediction in social media. (United States)

    Lima, Ana Carolina E S; de Castro, Leandro Nunes


    Social media allow web users to create and share content pertaining to different subjects, exposing their activities, opinions, feelings and thoughts. In this context, online social media has attracted the interest of data scientists seeking to understand behaviours and trends, whilst collecting statistics for social sites. One potential application for these data is personality prediction, which aims to understand a user's behaviour within social media. Traditional personality prediction relies on users' profiles, their status updates, the messages they post, etc. Here, a personality prediction system for social media data is introduced that differs from most approaches in the literature, in that it works with groups of texts, instead of single texts, and does not take users' profiles into account. Also, the proposed approach extracts meta-attributes from texts and does not work directly with the content of the messages. The set of possible personality traits is taken from the Big Five model and allows the problem to be characterised as a multi-label classification task. The problem is then transformed into a set of five binary classification problems and solved by means of a semi-supervised learning approach, due to the difficulty in annotating the massive amounts of data generated in social media. In our implementation, the proposed system was trained with three well-known machine-learning algorithms, namely a Naïve Bayes classifier, a Support Vector Machine, and a Multilayer Perceptron neural network. The system was applied to predict the personality of Tweets taken from three datasets available in the literature, and resulted in an approximately 83% accurate prediction, with some of the personality traits presenting better individual classification rates than others.

  4. Solid phase characterization and gas transfers through unsaturated porous media: experimental study and modeling applied diffusion of hydrogen through cement-based materials; Caracterisation de la phase solide et transferts de gaz dans les milieux poreux insatures: etude experimentale et modelisation appliquees a la diffusion de l'hydrogene dans les materiaux cimentaires

    Energy Technology Data Exchange (ETDEWEB)

    Vu, T.H.


    This thesis documents the relationship between the porous microstructure of cement based materials and theirs gaseous diffusivity properties relative to the aqueous phase location and the global saturation level of the material. The materials studied are cement pastes and mortars. To meet the thesis objective, the materials are characterized in detail by means of several experimental methods: mercury intrusion porosimetry, water porosimetry, thermo-poro-metry, nitrogen sorption and water desorption. In addition, diffusion tests realized on materials maintained in controlled humidity chambers allow obtaining the effective hydrogen diffusivity as function of the microstructure and the saturation state of material with a gas chromatography. The experimental results are then used as a data base that is compared to a modeling approach. The model developed consists of a combination of ordinary diffusion (Fick regime) and Knudsen diffusion of hydrogen. The model also accounts for the effects of the liquid curtains, the impact of tortuosity on gas diffusion, and the saturation level of the porous system. (author)

  5. Applying a Bayesian Approach to Identification of Orthotropic Elastic Constants from Full Field Displacement Measurements

    Directory of Open Access Journals (Sweden)

    Le Riche R.


    Full Text Available A major challenge in the identification of material properties is handling different sources of uncertainty in the experiment and the modelling of the experiment for estimating the resulting uncertainty in the identified properties. Numerous improvements in identification methods have provided increasingly accurate estimates of various material properties. However, characterizing the uncertainty in the identified properties is still relatively crude. Different material properties obtained from a single test are not obtained with the same confidence. Typically the highest uncertainty is associated with respect to properties to which the experiment is the most insensitive. In addition, the uncertainty in different properties can be strongly correlated, so that obtaining only variance estimates may be misleading. A possible approach for handling the different sources of uncertainty and estimating the uncertainty in the identified properties is the Bayesian method. This method was introduced in the late 1970s in the context of identification [1] and has been applied since to different problems, notably identification of elastic constants from plate vibration experiments [2]-[4]. The applications of the method to these classical pointwise tests involved only a small number of measurements (typically ten natural frequencies in the previously cited vibration test which facilitated the application of the Bayesian approach. For identifying elastic constants, full field strain or displacement measurements provide a high number of measured quantities (one measurement per image pixel and hence a promise of smaller uncertainties in the properties. However, the high number of measurements represents also a major computational challenge in applying the Bayesian approach to full field measurements. To address this challenge we propose an approach based on the proper orthogonal decomposition (POD of the full fields in order to drastically reduce their

  6. Applying a Bayesian Approach to Identification of Orthotropic Elastic Constants from Full Field Displacement Measurements (United States)

    Gogu, C.; Yin, W.; Haftka, R.; Ifju, P.; Molimard, J.; Le Riche, R.; Vautrin, A.


    A major challenge in the identification of material properties is handling different sources of uncertainty in the experiment and the modelling of the experiment for estimating the resulting uncertainty in the identified properties. Numerous improvements in identification methods have provided increasingly accurate estimates of various material properties. However, characterizing the uncertainty in the identified properties is still relatively crude. Different material properties obtained from a single test are not obtained with the same confidence. Typically the highest uncertainty is associated with respect to properties to which the experiment is the most insensitive. In addition, the uncertainty in different properties can be strongly correlated, so that obtaining only variance estimates may be misleading. A possible approach for handling the different sources of uncertainty and estimating the uncertainty in the identified properties is the Bayesian method. This method was introduced in the late 1970s in the context of identification [1] and has been applied since to different problems, notably identification of elastic constants from plate vibration experiments [2]-[4]. The applications of the method to these classical pointwise tests involved only a small number of measurements (typically ten natural frequencies in the previously cited vibration test) which facilitated the application of the Bayesian approach. For identifying elastic constants, full field strain or displacement measurements provide a high number of measured quantities (one measurement per image pixel) and hence a promise of smaller uncertainties in the properties. However, the high number of measurements represents also a major computational challenge in applying the Bayesian approach to full field measurements. To address this challenge we propose an approach based on the proper orthogonal decomposition (POD) of the full fields in order to drastically reduce their dimensionality. POD is

  7. A Monte Carlo approach applied to ultrasonic non-destructive testing (United States)

    Mosca, I.; Bilgili, F.; Meier, T.; Sigloch, K.


    Non-destructive testing based on ultrasound allows us to detect, characterize and size discrete flaws in geotechnical and architectural structures and materials. This information is needed to determine whether such flaws can be tolerated in future service. In typical ultrasonic experiments, only the first-arriving P-wave is interpreted, and the remainder of the recorded waveform is neglected. Our work aims at understanding surface waves, which are strong signals in the later wave train, with the ultimate goal of full waveform tomography. At present, even the structural estimation of layered media is still challenging because material properties of the samples can vary widely, and good initial models for inversion do not often exist. The aim of the present study is to combine non-destructive testing with a theoretical data analysis and hence to contribute to conservation strategies of archaeological and architectural structures. We analyze ultrasonic waveforms measured at the surface of a variety of samples, and define the behaviour of surface waves in structures of increasing complexity. The tremendous potential of ultrasonic surface waves becomes an advantage only if numerical forward modelling tools are available to describe the waveforms accurately. We compute synthetic full seismograms as well as group and phase velocities for the data. We invert them for the elastic properties of the sample via a global search of the parameter space, using the Neighbourhood Algorithm. Such a Monte Carlo approach allows us to perform a complete uncertainty and resolution analysis, but the computational cost is high and increases quickly with the number of model parameters. Therefore it is practical only for defining the seismic properties of media with a limited number of degrees of freedom, such as layered structures. We have applied this approach to both synthetic layered structures and real samples. The former contributed to benchmark the propagation of ultrasonic surface

  8. Applying clustering approach in predictive uncertainty estimation: a case study with the UNEEC method (United States)

    Dogulu, Nilay; Solomatine, Dimitri; Lal Shrestha, Durga


    Within the context of flood forecasting, assessment of predictive uncertainty has become a necessity for most of the modelling studies in operational hydrology. There are several uncertainty analysis and/or prediction methods available in the literature; however, most of them rely on normality and homoscedasticity assumptions for model residuals occurring in reproducing the observed data. This study focuses on a statistical method analyzing model residuals without having any assumptions and based on a clustering approach: Uncertainty Estimation based on local Errors and Clustering (UNEEC). The aim of this work is to provide a comprehensive evaluation of the UNEEC method's performance in view of clustering approach employed within its methodology. This is done by analyzing normality of model residuals and comparing uncertainty analysis results (for 50% and 90% confidence level) with those obtained from uniform interval and quantile regression methods. An important part of the basis by which the methods are compared is analysis of data clusters representing different hydrometeorological conditions. The validation measures used are PICP, MPI, ARIL and NUE where necessary. A new validation measure linking prediction interval to the (hydrological) model quality - weighted mean prediction interval (WMPI) - is also proposed for comparing the methods more effectively. The case study is Brue catchment, located in the South West of England. A different parametrization of the method than its previous application in Shrestha and Solomatine (2008) is used, i.e. past error values in addition to discharge and effective rainfall is considered. The results show that UNEEC's notable characteristic in its methodology, i.e. applying clustering to data of predictors upon which catchment behaviour information is encapsulated, contributes increased accuracy of the method's results for varying flow conditions. Besides, classifying data so that extreme flow events are individually

  9. Structured assessment approach: Version I. Applied demonstration of output results. Volume 3

    Energy Technology Data Exchange (ETDEWEB)

    Parziale, A.A.; Sacks, 1.J.


    A methodology, the Structured Assessment Approach, has been developed for the assessment of the effectiveness of material control and accounting (MC and A) safeguards systems at nuclear fuel cycle facilities. This methodology has been refined into a computational tool, the SAA Version 1 computational package, that was used first to analyze a hypothetical fuel cycle facility (HFCF) and used more recently to assess operational nuclear plants. The Version 1 analysis package is designed to analyze safeguards systems that prevent the diversion of special nuclear material (SNM) from nuclear fuel cycle facilities and to provide assurance that diversion has not occurred. This report is the third volume, Applied Demonstration of Output Results, of a four-volume document. It presents the outputs for each of the four levels of the SAA Version 1 computational package. Two types of outputs are discussed: detailed output findings and summary output tables. The summary output tables are used to aggregate the detailed output findings in a condensed form for NRC analyst consumption. Specific output results are presented for an HFCF, which is described in Volume II.

  10. An interdisciplinary and experimental approach applied to an analysis of the communication of influence

    Directory of Open Access Journals (Sweden)

    Brigitte JUANALS


    Full Text Available This paper describes the added value of an interdisciplinary and experimental approach applied to an analysis of the inter-organizational communication of influence. The field analyzed is the international industrial standardization of societal security. A communicational problem has been investigated with an experimental method based on natural language processing and knowledge management tools. The purpose of the methodological framework is to clarify the way international standards are designed and the policies that are supported by these standards. Furthermore, strategies of influence of public and private stakeholders involved in the NGOs which produce these texts have also been studied. The means of inter-organizational communication between organizations (companies or governmental authorities and NGOs can be compared to the lobbying developed in the context of the construction of Europe and globalization. Understanding the prescriptive process has become a crucial issue for States, organizations and citizens. This research contributes to the critical assessment of the new industrial policies currently being developed from the point of view of their characteristics and the way they have been designed.

  11. Applying patient centered approach in management of pulmonary tuberculosis: A case report from Malaysia. (United States)

    Atif, M; Sulaiman, Sas; Shafi, Aa; Muttalif, Ar; Ali, I; Saleem, F


    A 24 year university student with history of productive cough was registered as sputum smear confirmed case of pulmonary tuberculosis. During treatment, patient suffered from itchiness associated with anti tuberculosis drugs and was treated with chlorpheniramine (4mg) tablet. Patient missed twenty eight doses of anti tuberculosis drugs in continuation phase claiming that he was very busy in his studies and assignments. Upon questioning he further explained that he was quite healthy after five months and unable to concentrate on his studies after taking prescribed medicines. His treatment was stopped based on clinical improvement, although he did not complete six months therapy. Two major reasons; false perception of being completely cured and side effects associated with anti TB drugs might be responsible for non adherence. Non sedative anti histamines like fexofenadine, citrizine or loratidine should be preferred over first generation anti histamines (chlorpheniramine) in patients with such lifestyle. Patient had not completed full course of chemotherapy, which is preliminary requirement for a case to be classified as "cure" and "treatment completed". Moreover, patient had not defaulted for two consecutive months. Therefore, according to WHO treatment outcome categories, this patient can neither be classified as "cure" or "treatment completed" nor as "defaulter". Further elaboration of WHO treatment outcome categories is required for adequate classification of patients with similar characteristics. Likelihood of non adherence can be significantly reduced by applying the WHO recommended "Patient Centered Approach" strategy. Close friend, class mate or family member can be selected as treatment supporter to ensure adherence to treatment.

  12. Extraction of thermal Green's function using diffuse fields: a passive approach applied to thermography (United States)

    Capriotti, Margherita; Sternini, Simone; Lanza di Scalea, Francesco; Mariani, Stefano


    In the field of non-destructive evaluation, defect detection and visualization can be performed exploiting different techniques relying either on an active or a passive approach. In the following paper the passive technique is investigated due to its numerous advantages and its application to thermography is explored. In previous works, it has been shown that it is possible to reconstruct the Green's function between any pair of points of a sensing grid by using noise originated from diffuse fields in acoustic environments. The extraction of the Green's function can be achieved by cross-correlating these random recorded waves. Averaging, filtering and length of the measured signals play an important role in this process. This concept is here applied in an NDE perspective utilizing thermal fluctuations present on structural materials. Temperature variations interacting with thermal properties of the specimen allow for the characterization of the material and its health condition. The exploitation of the thermographic image resolution as a dense grid of sensors constitutes the basic idea underlying passive thermography. Particular attention will be placed on the creation of a proper diffuse thermal field, studying the number, placement and excitation signal of heat sources. Results from numerical simulations will be presented to assess the capabilities and performances of the passive thermal technique devoted to defect detection and imaging of structural components.

  13. Old concepts, new molecules and current approaches applied to the bacterial nucleotide signalling field (United States)


    Signalling nucleotides are key molecules that help bacteria to rapidly coordinate cellular pathways and adapt to changes in their environment. During the past 10 years, the nucleotide signalling field has seen much excitement, as several new signalling nucleotides have been discovered in both eukaryotic and bacterial cells. The fields have since advanced quickly, aided by the development of important tools such as the synthesis of modified nucleotides, which, combined with sensitive mass spectrometry methods, allowed for the rapid identification of specific receptor proteins along with other novel genome-wide screening methods. In this review, we describe the principle concepts of nucleotide signalling networks and summarize the recent work that led to the discovery of the novel signalling nucleotides. We also highlight current approaches applied to the research in the field as well as resources and methodological advances aiding in a rapid identification of nucleotide-specific receptor proteins. This article is part of the themed issue ‘The new bacteriology’. PMID:27672152

  14. Distribution function approach to redshift space distortions. Part V: perturbation theory applied to dark matter halos

    CERN Document Server

    Vlah, Zvonimir; Okumura, Teppei; Desjacques, Vincent


    Numerical simulations show that redshift space distortions (RSD) introduce strong scale dependence in the power spectra of halos, with ten percent deviations relative to linear theory predictions even on relatively large scales (k<0.1h/Mpc) and even in the absence of satellites (which induce Fingers-of-God, FoG, effects). If unmodeled these effects prevent one from extracting cosmological information from RSD surveys. In this paper we use perturbation theory (PT) and halo biasing model and apply it to the distribution function approach to RSD, in which RSD is decomposed into several correlators of density weighted velocity moments. We model each of these correlators using PT and compare the results to simulations over a wide range of halo masses and redshifts. We find that with an introduction of a physically motivated halo biasing, and using dark matter power spectra from simulations, we can reproduce the simulation results at a percent level on scales up to k~0.15h/Mpc at z=0, without the need to have fr...

  15. Applied tagmemics: A heuristic approach to the use of graphic aids in technical writing (United States)

    Brownlee, P. P.; Kirtz, M. K.


    In technical report writing, two needs which must be met if reports are to be useable by an audience are the language needs and the technical needs of that particular audience. A heuristic analysis helps to decide the most suitable format for information; that is, whether the information should be presented verbally or visually. The report writing process should be seen as an organic whole which can be divided and subdivided according to the writer's purpose, but which always functions as a totality. The tagmemic heuristic, because it itself follows a process of deconstructing and reconstructing information, lends itself to being a useful approach to the teaching of technical writing. By applying the abstract questions this heuristic asks to specific parts of the report. The language and technical needs of the audience are analyzed by examining the viability of the solution within the givens of the corporate structure, and by deciding which graphic or verbal format will best suit the writer's purpose. By following such a method, answers which are both specific and thorough in their range of application are found.

  16. Multiple steady state current-voltage characteristics in drift-diffusion modelisation of N type and semi-insulating GaAs Gunn structures (United States)

    Manifacier, J. C.


    Theoretical and numerical investigations of carriers transport in N-Semi-Insulating (SI)-N and P-SI-P diodes is extended to the case of extrinsic (N type) or SI samples with Gunn like electric field dependent mobilities. The results obtained in a preceding publication [1] are valid as long as the bulk electric field does not increase above a threshold field E th associated with the beginning of negative electron differential mobility values: μ n,diff = ( dv n/ dE) diodes. SI(N -) characterizes a SI layer which keeps, under applied bias, a free electron concentration close to its thermal equilibrium value up to the beginning of electron space charge injection. A systematic study has been made by varying the contact boundary properties: flat band, metallic, N + or P +; the length of the sample and the electric parameters of the deep compensating trap of the SI layers. We show that these steady state numerical instabilities are related to the existence of multiple current-voltage solutions when numerical modelisation is made using the drift-diffusion model.

  17. An approach for evaluating the integrity of fuel applied in Innovative Nuclear Energy Systems

    Energy Technology Data Exchange (ETDEWEB)

    Nakae, Nobuo, E-mail: [Center for Research into Innovative Nuclear Energy System, Tokyo Institute of Technology, 2-12-1-N1-19, Ookayama, Meguro-ku, Tokyo 152-8550 (Japan); Ozawa, Takayuki [Advanced Nuclear System Research and Development Directorate, Japan Atomic Energy Agency, 4-33, Muramatsu, Tokai-mura, Ibaraki-ken 319-1194 (Japan); Ohta, Hirokazu; Ogata, Takanari [Nuclear Technology Research Laboratory, Central Research Institute of Electric Power Industry, 2-11-1, Iwado Kita, Komae-shi, Tokyo 201-8511 (Japan); Sekimoto, Hiroshi [Center for Research into Innovative Nuclear Energy System, Tokyo Institute of Technology, 2-12-1-N1-19, Ookayama, Meguro-ku, Tokyo 152-8550 (Japan)


    One of the important issues in the study of Innovative Nuclear Energy Systems is evaluating the integrity of fuel applied in Innovative Nuclear Energy Systems. An approach for evaluating the integrity of the fuel is discussed here based on the procedure currently used in the integrity evaluation of fast reactor fuel. The fuel failure modes determining fuel life time were reviewed and fuel integrity was analyzed and compared with the failure criteria. Metal and nitride fuels with austenitic and ferritic stainless steel (SS) cladding tubes were examined in this study. For the purpose of representative irradiation behavior analyses of the fuel for Innovative Nuclear Energy Systems, the correlations of the cladding characteristics were modeled based on well-known characteristics of austenitic modified 316 SS (PNC316), ferritic–martensitic steel (PNC–FMS) and oxide dispersion strengthened steel (PNC–ODS). The analysis showed that the fuel lifetime is limited by channel fracture which is a nonductile type (brittle) failure associated with a high level of irradiation-induced swelling in the case of austenitic steel cladding. In case of ferritic steel, on the other hand, the fuel lifetime is controlled by cladding creep rupture. The lifetime evaluated here is limited to 200 GW d/t, which is lower than the target burnup value of 500 GW d/t. One of the possible measures to extend the lifetime may be reducing the fuel smeared density and ventilating fission gas in the plenum for metal fuel and by reducing the maximum cladding temperature from 650 to 600 °C for both metal and nitride fuel.

  18. Heart Rate assessment by means of a novel approach applied to signals of different nature (United States)

    Cosoli, G.; Casacanditella, L.; Tomasini, EP; Scalise, L.


    Electrocardiographic (ECG) signal presents many clinically relevant features (e.g. QT-interval, that is the duration of the ventricular depolarization). A novel processing technique has been demonstrated to be capable to measure some important characteristics according to the morphology of the waveform. Basing on that, the aim of this work is to propose an improved algorithm and to prove its efficacy in the assessment of the subject’s Heart Rate (HR) in comparison to standard algorithms (i.e. Pan & Tompkins). Results obtained in experimentally collected ECG signals for the identification of the main feature (R-peak) are comparable to those obtained with the traditional approach (sensitivity of 99.55% and 99.95%, respectively). Moreover, the use of this algorithm has been broaden to signals coming from different biomedical sensors (based on optical, acoustical and mechanical principles), all related to blood flow, for the computation of HR. In particular, it has been employed to PCG (Phonocardiography), PPG (Photoplethysmography) and VCG (Vibrocardiography), where standard algorithms could not be widely applied. HR results from a measurement campaign on 8 healthy subjects have shown, with respect to ECG, deviations (calculated as 2σ) of ±3.3 bpm, ±2.3 bpm and ±1.5 bpm for PCG, PPG and VCG, respectively. In conclusion, it is possible to state that the adopted algorithm is able to measure HR accurately from different biosignals. Future work will involve the extraction of additional morphological features in order to characterise the waveforms more deeply and to better describe the subject’s health status.

  19. Features of applying systems approach for evaluating the reliability of cryogenic systems for special purposes

    Directory of Open Access Journals (Sweden)

    E. D. Chertov


    Full Text Available Summary. The analysis of cryogenic installations confirms objective regularity of increase in amount of the tasks solved by systems of a special purpose. One of the most important directions of development of a cryogenics is creation of installations for air separation product receipt, namely oxygen and nitrogen. Modern aviation complexes require use of these gases in large numbers as in gaseous, and in the liquid state. The onboard gas systems applied in aircraft of the Russian Federation are subdivided on: oxygen system; air (nitric system; system of neutral gas; fire-proof system. Technological schemes ADI are in many respects determined by pressure of compressed air or, in a general sense, a refrigerating cycle. For the majority ADI a working body of a refrigerating cycle the divided air is, that is technological and refrigerating cycles in installation are integrated. By this principle differentiate installations: low pressure; average and high pressure; with detander; with preliminary chilling. There is also insignificant number of the ADI types in which refrigerating and technological cycles are separated. These are installations with external chilling. For the solution of tasks of control of technical condition of the BRV hardware in real time and estimates of indicators of reliability it is offered to use multi-agent technologies. Multi-agent approach is the most acceptable for creation of SPPR for reliability assessment as allows: to redistribute processing of information on elements of system that leads to increase in overall performance; to solve a problem of accumulating, storage and recycling of knowledge that will allow to increase significantly efficiency of the solution of tasks of an assessment of reliability; to considerably reduce intervention of the person in process of functioning of system that will save time of the person of the making decision (PMD and will not demand from it special skills of work with it.

  20. Considerations in applying the general equilibrium approach to environmental health assessment. (United States)

    Wan, Yue; Yang, Hong-Wei; Masui, Toshihiko


    There are currently two commonly used approaches to assessing economic impacts of health damage resulting from environmental pollution: human capital approach (HCA) and willingness-to-pay (WTP). WTP can be further divided into averted expenditure approach (AEA), hedonic wage approach (HWA), contingent valuation approach (CVA) and hedonic price approach (HPA). A general review of the principles behind these approaches by the authors indicates that these methods are incapable of unveiling the mechanism of health impact from the point of view of national economy. On a basis of economic system, the shocks brought about by health effects of environmental pollution change the labor supply and medical expenditure, which in turn affects the level of production activity in each sector and the total final consumption pattern of the society. The general equilibrium approach within the framework of macroeconomic theory is able to estimate the health impact on national economy comprehensively and objectively. Its mechanism and applicability are discussed in detail by the authors.

  1. Considerations in Applying the General Equilibrium Approach to Environmental Health Assessment

    Institute of Scientific and Technical Information of China (English)



    There are currently two commonly used approaches to assessing economic impacts of health damage resulting from environmental pollution: human capital approach (HCA) and willingness-to-pay (WTP). WTP can be further divided into averted expenditure approach (AEA), hedonic wage approach (HWA), contingent valuation approach (CVA) and hedonic price approach (HPA). A general review of the principles behind these approaches by the authors indicates that these methods are incapable of unveiling the mechanism of health impact from the point of view of national economy. On a basis of economic system, the shocks brought about by health effects of environmental pollution change the labor supply and medical expenditure, which in turn affects the level of production activity in each sector and the total final consumption pattern of the society. The general equilibrium approach within the framework of macroeconomic theory is able to estimate the health impact on national economy comprehensively and objectively. Its mechanism and applicability are discussed in detail by the authors.

  2. Method developments approaches in supercritical fluid chromatography applied to the analysis of cosmetics. (United States)

    Lesellier, E; Mith, D; Dubrulle, I


    Analyses of complex samples of cosmetics, such as creams or lotions, are generally achieved by HPLC. These analyses are often multistep gradients, due to the presence of compounds with a large range of polarity. For instance, the bioactive compounds may be polar, while the matrix contains lipid components that are rather non-polar, thus cosmetic formulations are usually oil-water emulsions. Supercritical fluid chromatography (SFC) uses mobile phases composed of carbon dioxide and organic co-solvents, allowing for good solubility of both the active compounds and the matrix excipients. Moreover, the classical and well-known properties of these mobile phases yield fast analyses and ensure rapid method development. However, due to the large number of stationary phases available for SFC and to the varied additional parameters acting both on retention and separation factors (co-solvent nature and percentage, temperature, backpressure, flow rate, column dimensions and particle size), a simplified approach can be followed to ensure a fast method development. First, suited stationary phases should be carefully selected for an initial screening, and then the other operating parameters can be limited to the co-solvent nature and percentage, maintaining the oven temperature and back-pressure constant. To describe simple method development guidelines in SFC, three sample applications are discussed in this paper: UV-filters (sunscreens) in sunscreen cream, glyceryl caprylate in eye liner and caffeine in eye serum. Firstly, five stationary phases (ACQUITY UPC(2)) are screened with isocratic elution conditions (10% methanol in carbon dioxide). Complementary of the stationary phases is assessed based on our spider diagram classification which compares a large number of stationary phases based on five molecular interactions. Secondly, the one or two best stationary phases are retained for further optimization of mobile phase composition, with isocratic elution conditions or, when

  3. A multidating approach applied to historical slackwater flood deposits of the Gardon River, SE France (United States)

    Dezileau, L.; Terrier, B.; Berger, J. F.; Blanchemanche, P.; Latapie, A.; Freydier, R.; Bremond, L.; Paquier, A.; Lang, M.; Delgado, J. L.


    A multidating approach was carried out on slackwater flood deposits, preserved in valley side rock cave and terrace, of the Gardon River in Languedoc, southeast France. Lead-210, caesium-137, and geochemical analysis of mining-contaminated slackwater flood sediments have been used to reconstruct the history of these flood deposits. These age controls were combined with the continuous record of Gardon flow since 1890, and the combined records were then used to assign ages to slackwater deposits. The stratigraphic records of terrace GE and cave GG were excellent examples to illustrate the effects of erosion/preservation in a context of a progressively self-censoring, vertically accreting sequence. The sedimentary flood record of the terrace GE located at 10 m above the channel bed is complete for years post-1958 but incomplete before. During the 78-year period 1880-1958, 25 floods of a sufficient magnitude (> 1450 m3/s) have covered the terrace. Since 1958, however, the frequency of inundation of the deposits has been lower: only 5 or 6 floods in 52 years have been large enough to exceed the necessary threshold discharge (> 1700 m3/s). The progressive increase of the threshold discharge and the reduced frequency of inundation at the terrace could allow stabilization of the vegetation cover and improve protection against erosion from subsequent large magnitude flood events. The sedimentary flood record seems complete for cave GG located at 15 m above the channel bed. Here, the low frequency of events would have enabled a high degree of stabilization of the sedimentary flood record, rendering the deposits less susceptible to erosion. Radiocarbon dating is used in this study and compared to the other dating techniques. Eighty percent of radiocarbon dates on charcoals were considerably older than those obtained by the other techniques in the terrace. On the other hand, radiocarbon dating on seeds provided better results. This discrepancy between radiocarbon dates on

  4. A Computer-Assisted Approach for Conducting Information Technology Applied Instructions (United States)

    Chu, Hui-Chun; Hwang, Gwo-Jen; Tsai, Pei Jin; Yang, Tzu-Chi


    The growing popularity of computer and network technologies has attracted researchers to investigate the strategies and the effects of information technology applied instructions. Previous research has not only demonstrated the benefits of applying information technologies to the learning process, but has also revealed the difficulty of applying…

  5. Text Classification: A Sequential Reading Approach

    CERN Document Server

    Dulac-Arnold, Gabriel; Gallinari, Patrick


    We propose to model the text classification process as a sequential decision process. In this process, an agent learns to classify documents into topics while reading the document sentences sequentially and learns to stop as soon as enough information was read for deciding. The proposed algorithm is based on a modelisation of Text Classification as a Markov Decision Process and learns by using Reinforcement Learning. Experiments on four different classical mono-label corpora show that the proposed approach performs comparably to classical SVM approaches for large training sets, and better for small training sets. In addition, the model automatically adapts its reading process to the quantity of training information provided.

  6. Developing and Applying Green Building Technology in an Indigenous Community: An Engaged Approach to Sustainability Education (United States)

    Riley, David R.; Thatcher, Corinne E.; Workman, Elizabeth A.


    Purpose: This paper aims to disseminate an innovative approach to sustainability education in construction-related fields in which teaching, research, and service are integrated to provide a unique learning experience for undergraduate students, faculty members, and community partners. Design/methodology/approach: The paper identifies the need for…

  7. Fuel moisture content estimation: a land-surface modelling approach applied to African savannas (United States)

    Ghent, D.; Spessa, A.; Kaduk, J.; Balzter, H.


    Despite the importance of fire to the global climate system, in terms of emissions from biomass burning, ecosystem structure and function, and changes to surface albedo, current land-surface models do not adequately estimate key variables affecting fire ignition and propagation. Fuel moisture content (FMC) is considered one of the most important of these variables (Chuvieco et al., 2004). Biophysical models, with appropriate plant functional type parameterisations, are the most viable option to adequately predict FMC over continental scales at high temporal resolution. However, the complexity of plant-water interactions, and the variability associated with short-term climate changes, means it is one of the most difficult fire variables to quantify and predict. Our work attempts to resolve this issue using a combination of satellite data and biophysical modelling applied to Africa. The approach we take is to represent live FMC as a surface dryness index; expressed as the ratio between the Normalised Difference Vegetation Index (NDVI) and land-surface temperature (LST). It has been argued in previous studies (Sandholt et al., 2002; Snyder et al., 2006), that this ratio displays a statistically stronger correlation to FMC than either of the variables, considered separately. In this study, simulated FMC is constrained through the assimilation of remotely sensed LST and NDVI data into the land-surface model JULES (Joint-UK Land Environment Simulator). Previous modelling studies of fire activity in Africa savannas, such as Lehsten et al. (2008), have reported significant levels of uncertainty associated with the simulations. This uncertainty is important because African savannas are among some of the most frequently burnt ecosystems and are a major source of greenhouse trace gases and aerosol emissions (Scholes et al., 1996). Furthermore, regional climate model studies indicate that many parts of the African savannas will experience drier and warmer conditions in future

  8. Benefits of collaborative learning for environmental management: applying the integrated systems for knowledge management approach to support animal pest control. (United States)

    Allen, W; Bosch, O; Kilvington, M; Oliver, J; Gilbert, M


    Resource management issues continually change over time in response to coevolving social, economic, and ecological systems. Under these conditions adaptive management, or "learning by doing," offers an opportunity for more proactive and collaborative approaches to resolving environmental problems. In turn, this will require the implementation of learning-based extension approaches alongside more traditional linear technology transfer approaches within the area of environmental extension. In this paper the Integrated Systems for Knowledge Management (ISKM) approach is presented to illustrate how such learning-based approaches can be used to help communities develop, apply, and refine technical information within a larger context of shared understanding. To outline how this works in practice, we use a case study involving pest management. Particular attention is paid to the issues that emerge as a result of multiple stakeholder involvement within environmental problem situations. Finally, the potential role of the Internet in supporting and disseminating the experience gained through ongoing adaptive management processes is examined.

  9. Applying Agile Requirements Engineering Approach for Re-engineering & Changes in existing Brownfield Adaptive Systems


    Masood, Abdullah; Ali, M. Asim


    Requirements Engineering (RE) is a key activity in the development of software systems and is concerned with the identification of the goals of stakeholders and their elaboration into precise statements of desired services and behavior. The research describes an Agile Requirements Engineering approach for re-engineering & changes in existing Brownfield adaptive system. The approach has few modifications that can be used as a part of SCRUM development process for re-engineering & changes. The ...

  10. Private pediatric neuropsychology practice multimodal treatment of ADHD: an applied approach. (United States)

    Beljan, Paul; Bree, Kathleen D; Reuter, Alison E F; Reuter, Scott D; Wingers, Laura


    As neuropsychologists and psychologists specializing in the assessment and treatment of pediatric mental health concerns, one of the most prominent diagnoses we encounter is attention-deficit hyperactivity disorder (ADHD). Following a pediatric neuropsychological evaluation, parents often request recommendations for treatment. This article addresses our approach to the treatment of ADHD from the private practice perspective. We will review our primary treatment methodology as well as integrative and alternative treatment approaches.

  11. An Optimisation Approach Applied to Design the Hydraulic Power Supply for a Forklift Truck

    DEFF Research Database (Denmark)

    Pedersen, Henrik Clemmensen; Andersen, Torben Ole; Hansen, Michael Rygaard


    -level optimisation approach, and is in the current paper exemplified through the design of the hydraulic power supply for a forklift truck. The paper first describes the prerequisites for the method and then explains the different steps in the approach to design the hydraulic system. Finally the results...... of the optimisation example for the forklift truck are presented along with a discussion of the method....

  12. Applying a Contest to Improve Learning in the Information Systems Development - An Interdisciplinary and Extracurricular Approach

    Directory of Open Access Journals (Sweden)

    Marcelo FANTINATO


    Full Text Available Contests are usually applied in the academic environment to simulate real professional situations that require from the participants a more pro-active attitude than the one shown in conventional coursework. Although they are commonly applied in the scope of a unique course, the contest described here was an extracurricular experience applied in an Information System undergraduate program. The evaluation of the contest is also presented; the objective was to assess the role of the contest as a tool to bring together interdisciplinary subjects, complementary to the traditional disciplinary structure of the program curriculum. The results indicate that a significant portion of the participants noticed increase in their knowledge after the contest, which is verified by statistical tests. However, students from the first stages received more benefits, probably because such students were more motivated and had more available time to be involved in the contest activities.

  13. Applying Research to Teacher Education: The University of Utah's Collaborative Approach. First Year Preliminary Report. (United States)

    Driscoll, Amy

    In 1983, the National Institute of Education funded the Far West Laboratory for Educational Research and Development to conduct a study, Applying Research to Teacher Education (ARTE) Research Utilization in Elementary Teacher Education (RUETE). The ARTE:RUETE study's purpose is to develop preservice instruction incorporating current research…

  14. A Transfer Learning Approach for Applying Matrix Factorization to Small ITS Datasets (United States)

    Voß, Lydia; Schatten, Carlotta; Mazziotti, Claudia; Schmidt-Thieme, Lars


    Machine Learning methods for Performance Prediction in Intelligent Tutoring Systems (ITS) have proven their efficacy; specific methods, e.g. Matrix Factorization (MF), however suffer from the lack of available information about new tasks or new students. In this paper we show how this problem could be solved by applying Transfer Learning (TL),…

  15. Applying Rawlsian Approaches to Resolve Ethical Issues: Inventory and Setting of a Research Agenda

    NARCIS (Netherlands)

    Doorn, N.


    Insights from social science are increasingly used in the field of applied ethics. However, recent insights have shown that the empirical branch of business ethics lacks thorough theoretical grounding. This article discusses the use of the Rawlsian methods of wide reflective equilibrium and overlapp

  16. Understanding the Conceptual Development Phase of Applied Theory-Building Research: A Grounded Approach (United States)

    Storberg-Walker, Julia


    This article presents a provisional grounded theory of conceptual development for applied theory-building research. The theory described here extends the understanding of the components of conceptual development and provides generalized relations among the components. The conceptual development phase of theory-building research has been widely…

  17. Regulation of the inter-provincial establishment of companies: applying the private interest approach to China

    NARCIS (Netherlands)

    Shen, Guang; Philipsen, N.J.; Philipsen, N.J.; Weishaar, S.E.; Xu, G.


    Existing empirical evidence shows that Chinese companies sometimes face difficulties when they try to establish themselves across provinces in China. A significant cause of this problem is the way in which local authorities apply the existing rules on inter-provincial establishment of companies. Mor

  18. Nonlinear approaches in engineering applications applied mechanics, vibration control, and numerical analysis

    CERN Document Server

    Jazar, Reza


    This book focuses on the latest applications of nonlinear approaches in different disciplines of engineering. For each selected topic, detailed concept development, derivations, and relevant knowledge are provided for the convenience of the readers. The topics range from dynamic systems and control to optimal approaches in nonlinear dynamics. The volume includes invited chapters from world class experts in the field. The selected topics are of great interest in the fields of engineering and physics and this book is ideal for engineers and researchers working in a broad range of practical topics and approaches. This book also: ·         Explores the most up-to-date applications and underlying principles of nonlinear approaches to problems in engineering and physics, including sections on analytic nonlinearity and practical nonlinearity ·         Enlightens readers to the conceptual significance of nonlinear approaches with examples of applications in scientific and engineering problems from v...

  19. Approach to hp10nm resolution by applying Dry Development Rinse Process (DDRP) and Materials (DDRM) (United States)

    Shibayama, Wataru; Shigaki, Shuhei; Takeda, Satoshi; Onishi, Ryuji; Nakajima, Makoto; Sakamoto, Rikimaru


    EUV lithography has been desired as the leading technology for single nm half-pitch patterning. However, the source power, masks and resist materials still have critical issues for mass production. Especially in resist materials, RLS trade-off is the key issue. To overcome this issue, we are suggesting Dry Development Rinse Process (DDRP) and Materials (DDRM) as the pattern collapse mitigation approach. This DDRM can perform not only as pattern collapse free materials for fine pitch, but also as the etching hard mask against bottom layer (spin on carbon : SOC). In this paper, we especially propose new approaches to achieve high resolution around hp10nm. The key points of our concepts are 1) control PR profiles, 2) new solvent system to avoid chemical mixture, 3) high etching selective DDR materilas and 4) high planar DDR materials. This new DDRM technology can be the promising approach for hp10nm level patterning in N7/N5 and beyond.

  20. Characterization of remarkable floods in France, a transdisciplinary approach applied on generalized floods of January 1910 (United States)

    Boudou, Martin; Lang, Michel; Vinet, Freddy; Coeur, Denis


    emphasize one flood typology or one flood dynamic (for example flash floods are often over-represented than slow dynamic floods in existing databases). Thus, the selected criteria have to introduce a general overview of flooding risk in France by integrating all typologies: storm surges, torrential floods, rising groundwater level and resulting to flood, etc. The methodology developed for the evaluation grid is inspired by several scientific works related to historical hydrology (Bradzil, 2006; Benito et al., 2004) or extreme floods classification (Kundzewics et al. 2013; Garnier E., 2005). The referenced information are mainly issued from investigations realized for the PFRA (archives, local data),from internet databases on flooding disasters, and from a complementary bibliography (some scientists such as Maurice Pardé a geographer who largely documented French floods during the 20th century). The proposed classification relies on three main axes. Each axis is associated to a set of criteria, each one related to a score (from 0.5 to 4 points), and pointing out a final remarkability score. • The flood intensity characterizing the flood's hazard level. It is composed of the submersion duration, important to valorize floods with slow dynamics as flooding from groundwater, the event peak discharge's return period, and the presence of factors increasing significantly the hazard level (dykes breaks, log jam, sediment transport…) • The flood severity focuses on economic damages, social and political repercussions, media coverage of the event, fatalities number or eventual flood warning failures. Analyzing the flood consequences is essential in order to evaluate the vulnerability of society at disaster date. • The spatial extension of the flood, which contributes complementary information to the two first axes. The evaluation grid was tested and applied on the sample of 176 remarkable events. Around twenty events (from 1856 to 2010) come out with a high remarkability rate

  1. Approach of Separately Applying Unit Testing to AspectJ Program

    Institute of Scientific and Technical Information of China (English)

    GU Hai-bo; LU Yan-sheng


    A unit testing approach for AspectJ programs is proposed to separately test aspect units which have their own states. In the approach, aspects under test are converted to classes before execution of unit testing. In the conversion process, the context information passed through pointcut is transformed into advices, then the advices are converted to class member methods, and conflicts in the conversion result, if any, are resolved finally. The unit testing process consists of generating test cases, executing test cases and checking results.

  2. Formation Feedback Applied to Behavior-Based Approach to Formation Keeping

    Institute of Scientific and Technical Information of China (English)

    苏治宝; 陆际联


    Approaches to the study of formation keeping for multiple mobile robots are analyzed and a behavior-based robot model is built in this paper. And, a kind of coordination architecture is presented, which is similar to the infantry squad organization and is used to realize multiple mobile robots to keep formations. Simulations verify the validity of the approach to keep formation, which combines the behavior-based method and formation feedback. The effects of formation feedback on the performance of the system are analyzed.

  3. Creating patient value in glaucoma care : applying quality costing and care delivery value chain approaches

    NARCIS (Netherlands)

    D.F. de Korne (Dirk); J.C.A. Sol (Kees); T. Custers (Thomas); E. van Sprundel (Esther); B.M. van Ineveld (Martin); H.G. Lemij (Hans); N.S. Klazinga (Niek)


    textabstractPurpose: The purpose of this paper is to explore in a specific hospital care process the applicability in practice of the theories of quality costing and value chains. Design/methodology/approach: In a retrospective case study an in-depth evaluation of the use of a quality cost model (QC

  4. What Are the Learning Approaches Applied by Undergraduate Students in English Process Writing Based on Gender? (United States)

    Veloo, Arsaythamby; Krishnasamy, Hariharan N.; Harun, Hana Mulyani


    The purpose of this study is to determine gender differences and type of learning approaches among Universiti Utara Malaysia (UUM) undergraduate students in English writing performance. The study involved 241 (32.8% male & 67.2% female) undergraduate students of UUM who were taking the Process Writing course. This study uses a Two-Factor Study…

  5. Investigation of Fire Growth and Spread in a Model-Scale Railcar Using an Applied Approach

    Directory of Open Access Journals (Sweden)

    Ali Kazemipour


    Full Text Available Fire is a potential hazard in public transportation facilities such as subways or road tunnels due to its contribution to high number of deaths. To provide an insight into fire development behavior in tunnels which can serve as the basis for emergency ventilation design, model-scale railcar fire is explored numerically in this research. Fire growth and its spread are investigated by analyzing the HRR curve as the representative of fire behavior in different stages. Fire development has been predicted through a new approach using an Arrhenius-based pyrolysis model, established to predict the decomposition behavior of solid flammable materials exposed to heat flux. Using this approach, model-scale railcar fire curve is obtained and compared with experimental data. Reasonable agreement is achieved in two important stages of flashover and fully developed fire, confirming the accuracy of the presented approach. Moreover, effects of railcar material type, amount of available air, and surrounding are also discussed. Detailed illustrations of physical phenomena and flow structures have been provided and justified with experimental findings for better description of railcar fire behavior. The presented approach can be further used in other applications such as investigation of fire spread in a compartment, studying fire spread from a burning vehicle to another and reconstruction of fire incidents.

  6. Applying a Competency- and Problem-Based Approach for Learning Compiler Design (United States)

    Khoumsi, Ahmed; Gonzalez-Rubio, Ruben


    Our department has redesigned its electrical engineering and computer engineering programs completely by adopting a learning methodology based on competence development, problem solving, and the realization of design projects. In this article, we show how this pedagogical approach has been successfully used for learning compiler design.

  7. Applying Self-Efficacy Theory to Counselor Training and Supervision: A Comparison of Two Approaches (United States)

    Barnes, Kristin L.


    Counseling self-efficacy, an individual's perception of his or her competence to conduct counseling, is an important component of understanding how counselor trainees subjectively construct their counseling and training experiences and subsequently develop into competent counseling professionals. The author describes 2 approaches to using…

  8. Applying the Recovery Approach to the Interface between Mental Health and Child Protection Services (United States)

    Duffy, Joe; Davidson, Gavin; Kavanagh, Damien


    There is a range of theoretical approaches which may inform the interface between child protection and adult mental health services. These theoretical perspectives tend to be focused on either child protection or mental health with no agreed integrating framework. The interface continues to be identified, in research, case management reviews and…

  9. Should Humanism Approach Be Applied in English as a Second Language (ESL) Classrooms? (United States)

    Ling, Lee Yi; Jin, Ng Yu; Tong, Chong Seng; Tarmizi, Mohd. Ariff


    In the process of learning, many elements fall into place wholly in order to enhance effectiveness. These elements include not only environmental factors but also learners' mentality which involves their feelings, needs and interests. Humanism approach is one which caters these elements required by learners' learning process through emphasis on…

  10. Applying Hybrid Heuristic Approach to Identify Contaminant Source Information in Transient Groundwater Flow Systems

    Directory of Open Access Journals (Sweden)

    Hund-Der Yeh


    Full Text Available Simultaneous identification of the source location and release history in aquifers is complicated and time-consuming if the release of groundwater contaminant source varies in time. This paper presents an approach called SATSO-GWT to solve complicated source release problems which contain the unknowns of three location coordinates and several irregular release periods and concentrations. The SATSO-GWT combines with ordinal optimization algorithm (OOA, roulette wheel approach, and a source identification algorithm called SATS-GWT. The SATS-GWT was developed based on simulated annealing, tabu search, and three-dimensional groundwater flow and solute transport model MD2K-GWT. The OOA and roulette wheel method are utilized mainly to reduce the size of feasible solution domain and accelerate the identification of the source information. A hypothetic site with one contaminant source location and two release periods is designed to assess the applicability of the present approach. The results indicate that the performance of SATSO-GWT is superior to that of SATS-GWT. In addition, the present approach works very effectively in dealing with the cases which have different initial guesses of source location and measurement errors in the monitoring points as well as problems with large suspicious areas and several source release periods and concentrations.

  11. A Controllability Approach for Resonant Compliant Systems: Applied to a Flapping Wing Micro Air Vehicle

    NARCIS (Netherlands)

    Peters, H.J.


    This thesis studies a controllability approach for general resonant compliant systems. These systems exploit resonance to obtain a specific dynamic response at relatively low actuation power. This type of systems is often lightweight, is scalable and minimizes frictional losses through the use of co

  12. Improving the efficiency of a chemotherapy day unit: Applying a business approach to oncology

    NARCIS (Netherlands)

    Lent, van Wineke A.M.; Goedbloed, N.; Harten, van W.H.


    Aim: To improve the efficiency of a hospital-based chemotherapy day unit (CDU). - Methods: The CDU was benchmarked with two other CDUs to identify their attainable performance levels for efficiency, and causes for differences. Furthermore, an in-depth analysis using a business approach, called lean

  13. Applying Data Mining Techniques to Improve Information Security in the Cloud: A Single Cache System Approach

    Directory of Open Access Journals (Sweden)

    Amany AlShawi


    Full Text Available Presently, the popularity of cloud computing is gradually increasing day by day. The purpose of this research was to enhance the security of the cloud using techniques such as data mining with specific reference to the single cache system. From the findings of the research, it was observed that the security in the cloud could be enhanced with the single cache system. For future purposes, an Apriori algorithm can be applied to the single cache system. This can be applied by all cloud providers, vendors, data distributors, and others. Further, data objects entered into the single cache system can be extended into 12 components. Database and SPSS modelers can be used to implement the same.

  14. Evaluation of Jumping and Creeping Regularization Approaches Applied to 3D Seismic Tomography (United States)

    Liu, M.; Ramachandran, K.


    Regularization deals with the ill-posedness of the inverse problem. The under-determined part of the problem is controlled by providing a priori knowledge on the physical solution in the form of additional constraints that the solution must satisfy. The final model is constrained to fit the data and also to satisfy some additional property. In seismic tomography, this property is selected such that the final model is as smooth as possible. This concept is physically meaningful as smooth models are sought that include only structure that is required to fit the data according to its uncertainty. The motivation for seeking a smooth model is that features present in the model should be essential to match the observations. Such a class of models is referred to as minimum structure models. The amount of structure in the estimated model parameters is measured in terms of roughness. In seismic tomography, second spatial derivatives are generally employed to quantify the model roughness. In this kind of regularized inversion, an objective function is minimized which includes norms that measure model roughness and data misfit. A tradeoff parameter is selected that provides the model with the least structure for a given level of data misfit. The regularized inverse problem that solves for model perturbation and also constrains perturbation flatness or smoothness during the inversion is known as creeping approach. The disadvantage of the creeping approach is that the final model will have no special properties and will be just a sum of smooth deviations added to the starting model. The regularized inverse problem that solves for model perturbation and also constrains model properties during the inversion is known as creeping approach. In the jumping approach, the final model can be constructed to have properties such as flatness or smoothness, since the regularization implements smoothing constraints on the model and not on the perturbation. The jumping and creeping approaches

  15. A systematic approach for fine-tuning of fuzzy controllers applied to WWTPs

    DEFF Research Database (Denmark)

    Ruano, M.V.; Ribes, J.; Sin, Gürkan;


    A systematic approach for fine-tuning fuzzy controllers has been developed and evaluated for an aeration control system implemented in a WWTR The challenge with the application of fuzzy controllers to WWTPs is simply that they contain many parameters, which need to be adjusted for different WWTP...... applications. To this end, a methodology based on model simulations is used that employs three statistical methods: (i) Monte-Carlo procedure: to find proper initial conditions, (ii) Identifiability analysis: to find an identifiable parameter subset of the fuzzy controller and (iii) minimization algorithm......: to fine-tune the identifiable parameter subset of the controller. Indeed, the initial location found by Monte-Carlo simulations provided better results than using trial and error approach when identifying parameters of the fuzzy controller. The identifiable subset was reduced to 4 parameters from a total...


    Institute of Scientific and Technical Information of China (English)

    Xu Hongji; Liu Ju; Gu Bo


    An approach combining optimal antenna subset selection with blind detection scheme for Orthogonal Space-Time Block Coding (OSTBC) is proposed in this paper. The optimal antenna subset selection is taken into account at transmitter and/or receiver sides, which chooses the optimal antennas to increase the diversity order of OSTBC and improve further its performance. In order to enhance the robustness of the detection used in the conventional OSTBC scheme, a blind detection scheme based on Independent Component Analysis (ICA) is exploited which can directly extract transmitted signals without channel estimation. Performance analysis shows that the proposed approach can achieve the full diversity and the flexibility of system design by using the antenna selection and the ICA based blind detection schemes.


    DEFF Research Database (Denmark)

    Jørgensen, Kirsten


    Function failures, defects, mistakes and poor communication are major problems for the construction sector. A Danish research project focusing on failures and defects in building processes has been carried out over the last 2 years. As the empirical element in the research, a large construction...... site was observed from the very start to the very end and all failures and defects of a certain size were recorded and analysed. The methodological approach used in this analysis was the bow-tie model from the area of safety research. It combines critical-event analysis for both causes and effects...... with event-tree analysis. The paper describes this analytical approach as an introduction to a new concept for understanding failures and defects in construction. Analysing the many critical events in the building process with the bow-tie model visualises the complexity of causes. This visualisation offers...

  18. Applying sequential Monte Carlo methods into a distributed hydrologic model: lagged particle filtering approach with regularization

    Directory of Open Access Journals (Sweden)

    S. J. Noh


    Full Text Available Applications of data assimilation techniques have been widely used to improve hydrologic prediction. Among various data assimilation techniques, sequential Monte Carlo (SMC methods, known as "particle filters", provide the capability to handle non-linear and non-Gaussian state-space models. In this paper, we propose an improved particle filtering approach to consider different response time of internal state variables in a hydrologic model. The proposed method adopts a lagged filtering approach to aggregate model response until uncertainty of each hydrologic process is propagated. The regularization with an additional move step based on Markov chain Monte Carlo (MCMC is also implemented to preserve sample diversity under the lagged filtering approach. A distributed hydrologic model, WEP is implemented for the sequential data assimilation through the updating of state variables. Particle filtering is parallelized and implemented in the multi-core computing environment via open message passing interface (MPI. We compare performance results of particle filters in terms of model efficiency, predictive QQ plots and particle diversity. The improvement of model efficiency and the preservation of particle diversity are found in the lagged regularized particle filter.

  19. Applying sequential Monte Carlo methods into a distributed hydrologic model: lagged particle filtering approach with regularization

    Directory of Open Access Journals (Sweden)

    S. J. Noh


    Full Text Available Data assimilation techniques have received growing attention due to their capability to improve prediction. Among various data assimilation techniques, sequential Monte Carlo (SMC methods, known as "particle filters", are a Bayesian learning process that has the capability to handle non-linear and non-Gaussian state-space models. In this paper, we propose an improved particle filtering approach to consider different response times of internal state variables in a hydrologic model. The proposed method adopts a lagged filtering approach to aggregate model response until the uncertainty of each hydrologic process is propagated. The regularization with an additional move step based on the Markov chain Monte Carlo (MCMC methods is also implemented to preserve sample diversity under the lagged filtering approach. A distributed hydrologic model, water and energy transfer processes (WEP, is implemented for the sequential data assimilation through the updating of state variables. The lagged regularized particle filter (LRPF and the sequential importance resampling (SIR particle filter are implemented for hindcasting of streamflow at the Katsura catchment, Japan. Control state variables for filtering are soil moisture content and overland flow. Streamflow measurements are used for data assimilation. LRPF shows consistent forecasts regardless of the process noise assumption, while SIR has different values of optimal process noise and shows sensitive variation of confidential intervals, depending on the process noise. Improvement of LRPF forecasts compared to SIR is particularly found for rapidly varied high flows due to preservation of sample diversity from the kernel, even if particle impoverishment takes place.

  20. Applying the problem-based learning approach in teaching digital integrated circuit design


    Lei, CU


    The problem-based learning (PBL) method has been applied to curriculum development in some areas of electrical engineering. The overall result has been a positive learning experience for students. However, PBL has not, as yet, been used in the area of digital integrated circuit (IC) design. IC design is in a revolutionary phase at present. It could even be said that IC design is at the beginning of a new epoch. Design is moving toward nano-size. Thus, design techniques are advancing so rap...

  1. Optical waveguiding and applied photonics technological aspects, experimental issue approaches and measurements

    CERN Document Server

    Massaro, Alessandro


    Optoelectronics--technology based on applications light such as micro/nano quantum electronics, photonic devices, laser for measurements and detection--has become an important field of research. Many applications and physical problems concerning optoelectronics are analyzed in Optical Waveguiding and Applied Photonics.The book is organized in order to explain how to implement innovative sensors starting from basic physical principles. Applications such as cavity resonance, filtering, tactile sensors, robotic sensor, oil spill detection, small antennas and experimental setups using lasers are a

  2. A new applied approach for executing computations with infinite and infinitesimal quantities

    CERN Document Server

    Sergeyev, Yaroslav D


    A new computational methodology for executing calculations with infinite and infinitesimal quantities is described in this paper. It is based on the principle `The part is less than the whole' introduced by Ancient Greeks and applied to all numbers (finite, infinite, and infinitesimal) and to all sets and processes (finite and infinite). It is shown that it becomes possible to write down finite, infinite, and infinitesimal numbers by a finite number of symbols as particular cases of a unique framework. The new methodology has allowed us to introduce the Infinity Computer working with such numbers (its simulator has already been realized). Examples dealing with divergent series, infinite sets, and limits are given.

  3. The GRADE approach for assessing new technologies as applied to apheresis devices in ulcerative colitis

    Directory of Open Access Journals (Sweden)

    Cabriada-Nuño Jose


    Full Text Available Abstract Background In the last few years, a new non-pharmacological treatment, termed apheresis, has been developed to lessen the burden of ulcerative colitis (UC. Several methods can be used to establish treatment recommendations, but over the last decade an informal collaboration group of guideline developers, methodologists, and clinicians has developed a more sensible and transparent approach known as the Grading of Recommendations, Assessment, Development and Evaluation (GRADE. GRADE has mainly been used in clinical practice guidelines and systematic reviews. The aim of the present study is to describe the use of this approach in the development of recommendations for a new health technology, and to analyse the strengths, weaknesses, opportunities, and threats found when doing so. Methods A systematic review of the use of apheresis for UC treatment was performed in June 2004 and updated in May 2008. Two related clinical questions were selected, the outcomes of interest defined, and the quality of the evidence assessed. Finally, the overall quality of each question was taken into account to formulate recommendations following the GRADE approach. To evaluate this experience, a SWOT (strengths, weaknesses, opportunities and threats analysis was performed to enable a comparison with our previous experience with the SIGN (Scottish Intercollegiate Guidelines Network method. Results Application of the GRADE approach allowed recommendations to be formulated and the method to be clarified and made more explicit and transparent. Two weak recommendations were proposed to answer to the formulated questions. Some challenges, such as the limited number of studies found for the new technology and the difficulties encountered when searching for the results for the selected outcomes, none of which are specific to GRADE, were identified. GRADE was considered to be a more time-consuming method, although it has the advantage of taking into account patient

  4. The GRADE approach for assessing new technologies as applied to apheresis devices in ulcerative colitis (United States)


    Background In the last few years, a new non-pharmacological treatment, termed apheresis, has been developed to lessen the burden of ulcerative colitis (UC). Several methods can be used to establish treatment recommendations, but over the last decade an informal collaboration group of guideline developers, methodologists, and clinicians has developed a more sensible and transparent approach known as the Grading of Recommendations, Assessment, Development and Evaluation (GRADE). GRADE has mainly been used in clinical practice guidelines and systematic reviews. The aim of the present study is to describe the use of this approach in the development of recommendations for a new health technology, and to analyse the strengths, weaknesses, opportunities, and threats found when doing so. Methods A systematic review of the use of apheresis for UC treatment was performed in June 2004 and updated in May 2008. Two related clinical questions were selected, the outcomes of interest defined, and the quality of the evidence assessed. Finally, the overall quality of each question was taken into account to formulate recommendations following the GRADE approach. To evaluate this experience, a SWOT (strengths, weaknesses, opportunities and threats) analysis was performed to enable a comparison with our previous experience with the SIGN (Scottish Intercollegiate Guidelines Network) method. Results Application of the GRADE approach allowed recommendations to be formulated and the method to be clarified and made more explicit and transparent. Two weak recommendations were proposed to answer to the formulated questions. Some challenges, such as the limited number of studies found for the new technology and the difficulties encountered when searching for the results for the selected outcomes, none of which are specific to GRADE, were identified. GRADE was considered to be a more time-consuming method, although it has the advantage of taking into account patient values when defining and

  5. The Process of Laying Concrete and Analysis of Operations Applying the Lean Approach

    Directory of Open Access Journals (Sweden)

    Vidmantas Gramauskas


    Full Text Available The paper considers Lean philosophy ‘Just in Time’, a value stream map and total quality management principles applying them to the construction. In order to follow these principles, a case study was performed, thus observing and recording the process of laying concrete in three houses where a lower ground floor was casted employing fiber concrete. The collected data were required to fragment the process of laying concrete into smaller operations and examine each operation independently. The examination of operations was introduced in certain units of measurement – time, the number of workers, cubic meters of concrete used, space area, etc. This information helped with distinguishing useful operations from useless actions bringing no value to the product. The previously mentioned methods can be applied to useless operations to reduce their duration or even eliminate them. The main problem is the process of laying concrete splitting it into smaller operations, operation analysis and adaptation of Lean principles. The implementation of Lean system can reduce waste and increase the value of the final product.

  6. Applying a radiomics approach to predict prognosis of lung cancer patients (United States)

    Emaminejad, Nastaran; Yan, Shiju; Wang, Yunzhi; Qian, Wei; Guan, Yubao; Zheng, Bin


    Radiomics is an emerging technology to decode tumor phenotype based on quantitative analysis of image features computed from radiographic images. In this study, we applied Radiomics concept to investigate the association among the CT image features of lung tumors, which are either quantitatively computed or subjectively rated by radiologists, and two genomic biomarkers namely, protein expression of the excision repair cross-complementing 1 (ERCC1) genes and a regulatory subunit of ribonucleotide reductase (RRM1), in predicting disease-free survival (DFS) of lung cancer patients after surgery. An image dataset involving 94 patients was used. Among them, 20 had cancer recurrence within 3 years, while 74 patients remained DFS. After tumor segmentation, 35 image features were computed from CT images. Using the Weka data mining software package, we selected 10 non-redundant image features. Applying a SMOTE algorithm to generate synthetic data to balance case numbers in two DFS ("yes" and "no") groups and a leave-one-case-out training/testing method, we optimized and compared a number of machine learning classifiers using (1) quantitative image (QI) features, (2) subjective rated (SR) features, and (3) genomic biomarkers (GB). Data analyses showed relatively lower correlation among the QI, SR and GB prediction results (with Pearson correlation coefficients 0.5). Among them, using QI yielded the highest performance.

  7. Uncertainty Reduced Novelty Detection Approach Applied to Rotating Machinery for Condition Monitoring

    Directory of Open Access Journals (Sweden)

    S. Ma


    Full Text Available Novelty detection has been developed into a state-of-the-art technique to detect abnormal behavior and trigger alarm for in-field machine maintenance. With built-up models of normality, it has been widely applied to several situations with normal supervising dataset such as shaft rotating speed and component temperature available meanwhile in the absence of fault information. However, the research about vibration transmission based novelty detection remains unnoticed until recently. In this paper, vibration transmission measurement on rotor is performed; based on extreme value distributions, thresholds for novelty detection are calculated. In order to further decrease the false alarm rate, both measurement and segmentation uncertainty are considered, as they may affect threshold value and detection correctness heavily. Feasible reduction strategies are proposed and discussed. It is found that the associated multifractal coefficient and Kullback-Leibler Divergence operate well in the uncertainty reduction process. As shown by in situ applications to abnormal rotor with pedestal looseness, it is demonstrated that the abnormal states are detected. The higher specificity value proves the effectiveness of proposed uncertainty reduction method. This paper shows novel achievements of uncertainty reduced novelty detection applied to vibration signal in dynamical system and also sheds lights on its utilization in the field of health monitoring of rotating machinery.

  8. Skill-Based Approach Applied to Gifted Students, its Potential in Latin America

    Directory of Open Access Journals (Sweden)

    Andrew Alexi Almazán-Anaya


    Full Text Available This paper presents, as a reflective essay, the current educational situation of gifted students (with more intelligence than the average in Latin America and the possibility of using skill-based education within differentiated programs (intended for gifted individuals, a sector where scarce scientific studies have been done and a consensus of an ideal educative model has not been reached yet. Currently these students, in general, lack of specialized educational assistance intended to identify and develop their cognitive abilities, so it is estimated that a high percentage (95% of such population is not detected in the traditional education system. Although there are differentiated education models, they are rarely applied. A student-centered education program is a solution proposed to apply this pedagogical model and cover such population. The characteristics of this program that do support differentiated instruction for gifted individuals compatible with experiences in the US, Europe and Latin America are analyzed. Finally, this paper concludes with an analysis of possible research areas that, if explored in the future, would help us to find answers about the feasibility and relation between skill-based programs and differentiated education for gifted students.

  9. Applying adaptive management in resource use in South African National Parks: A case study approach

    Directory of Open Access Journals (Sweden)

    Kelly Scheepers


    Full Text Available South African National Parks (SANParks has a history of formal and informal natural resource use that is characterised by polarised views on national conservation interests and benefits to communities. Current efforts aim to determine the sustainability of existing resource use in parks and to formalise these activities through the development of resource use protocols. The resource use policy of SANParks outlines principles for sustainable resource use, including greater involvement of local communities in management of protected areas and an adaptive management approach to determining sustainable use levels. This paper examines three case studies on plant use in national parks with regard to the development of criteria and indicators for monitoring resource use, and the role of thresholds of potential concern in measuring effectiveness of managing for sustainable use levels. Opportunities and challenges for resource use management are identified. Findings show that platforms for discussion and knowledge sharing, including research committees and community associations, are critical to building relationships, trust and a shared vision of sustainable resource use between stakeholders. However, additional capacity building is needed to enable local community structures to manage internal social conflicts and jealousy, and to participate fully in monitoring efforts. Long-term monitoring is essential for developing flexible harvest prescriptions for plant use, but this is a time-consuming and resource-intensive exercise. Flexible management strategies are difficult to implement and sometimes command-and-control measures are necessary to protect rare or endangered species. A holistic approach that considers resource use in national parks as a complement to broader community development initiatives offers a way forward.Conservation implications: There is no blueprint for the development of sustainable resource use systems and resource use is often

  10. Analysis of the distributed computing approach applied to the folding of a small beta peptide. (United States)

    Paci, Emanuele; Cavalli, Andrea; Vendruscolo, Michele; Caflisch, Amedeo


    In the recently proposed distributed computing approach to protein folding a very large number of short independent simulations is performed. Using this method, folding events on a time scale orders of magnitude shorter than the experimental one have been reported. However, it has also been observed that the folding process is not an elementary kinetic step and that the presence of initial lag phases can bias short simulations toward atypical pathways. We study here a 20-residue three-stranded antiparallel beta-sheet peptide whose equilibrium properties can be characterized by atomistic molecular dynamics simulations. We found that the folding rate of this peptide is estimated correctly by the distributed computing approach when trajectories > approximately 1/100 of the equilibrium folding time are considered. We also found that the fastest folding events occur through high-energy pathways, which are unlikely under equilibrium conditions. These very fast folding pathways do not relax within the equilibrium denatured state that is stabilized by the transient presence of both native and non-native interactions, and they are characterized by the nearly simultaneous formation of the two beta-hairpins and a very small number of non-native contacts.

  11. Nonsingular terminal sliding mode approach applied to synchronize chaotic systems with unknown parameters and nonlinear inputs

    Institute of Scientific and Technical Information of China (English)

    Mohammad Pourmahmood Aghababa; Hassan Feizi


    This paper deals with the design of a novel nonsingular terminal sliding mode controller for finite-time synchronization of two different chaotic systems with fully unknown parameters and nonlinear inputs.We propose a novel nonsingular terminal sliding surface and prove its finite-time convergence to zero.We assume that both the master's and the slave's system parameters are unknown in advance.Proper adaptation laws are derived to tackle the unknown parameters.An adaptive sliding mode control law is designed to ensure the existence of the sliding mode in finite time.We prove that both reaching and sliding mode phases are stable in finite time.An estimation of convergence time is given.Two illustrative examples show the effectiveness and usefulness of the proposed technique.It is worthwhile noticing that the introduced nonsingular terminal sliding mode can be applied to a wide variety of nonlinear control problems.

  12. Method to integrate clinical guidelines into the electronic health record (EHR) by applying the archetypes approach. (United States)

    Garcia, Diego; Moro, Claudia Maria Cabral; Cicogna, Paulo Eduardo; Carvalho, Deborah Ribeiro


    Clinical guidelines are documents that assist healthcare professionals, facilitating and standardizing diagnosis, management, and treatment in specific areas. Computerized guidelines as decision support systems (DSS) attempt to increase the performance of tasks and facilitate the use of guidelines. Most DSS are not integrated into the electronic health record (EHR), ordering some degree of rework especially related to data collection. This study's objective was to present a method for integrating clinical guidelines into the EHR. The study developed first a way to identify data and rules contained in the guidelines, and then incorporate rules into an archetype-based EHR. The proposed method tested was anemia treatment in the Chronic Kidney Disease Guideline. The phases of the method are: data and rules identification; archetypes elaboration; rules definition and inclusion in inference engine; and DSS-EHR integration and validation. The main feature of the proposed method is that it is generic and can be applied toany type of guideline.


    Directory of Open Access Journals (Sweden)

    Sadia Aslam


    Full Text Available This paper presents a data hiding application for document images providing security. Document images should be in bitmap format as well as grayscale in nature otherwise the developed system will automatically change it to grayscale. The system accepts any grayscale document image as an input and applies the developed technique on it. Developed technique is based on Entropy Based that selects the suitable areas in an image for that data insertion purpose. Output produced by the system is the processed document that is data embedded. Processed document should not look different from the original image means its visual quality should be high. The system is successfully tested for the test cases generated to check the effectiveness, quality and validation of the system. The system is developed using Matlab 7.7.0 (R2008b for the development of front end as well as the back end.

  14. The possibilities of applying a risk-oriented approach to the NPP reliability and safety enhancement problem (United States)

    Komarov, Yu. A.


    An analysis and some generalizations of approaches to risk assessments are presented. Interconnection between different interpretations of the "risk" notion is shown, and the possibility of applying the fuzzy set theory to risk assessments is demonstrated. A generalized formulation of the risk assessment notion is proposed in applying risk-oriented approaches to the problem of enhancing reliability and safety in nuclear power engineering. The solution of problems using the developed risk-oriented approaches aimed at achieving more reliable and safe operation of NPPs is described. The results of studies aimed at determining the need (advisability) to modernize/replace NPP elements and systems are presented together with the results obtained from elaborating the methodical principles of introducing the repair concept based on the equipment technical state. The possibility of reducing the scope of tests and altering the NPP systems maintenance strategy is substantiated using the risk-oriented approach. A probabilistic model for estimating the validity of boric acid concentration measurements is developed.

  15. Developing scenarios to assess future landslide risks: a model-based approach applied to mountainous regions (United States)

    Vacquie, Laure; Houet, Thomas


    In the last century, European mountain landscapes have experienced significant transformations. Natural and anthropogenic changes, climate changes, touristic and industrial development, socio-economic interactions, and their implications in terms of LUCC (land use and land cover changes) have directly influenced the spatial organization and vulnerability of mountain landscapes. This study is conducted as part of the SAMCO project founded by the French National Science Agency (ANR). It aims at developing a methodological approach, combining various tools, modelling platforms and methods, to identify vulnerable regions to landslide hazards accounting for futures LUCC. It presents an integrated approach combining participative scenarios and a LULC changes simulation models to assess the combined effects of LUCC and climate change on landslide risks in the Cauterets valley (French Pyrenees Mountains) up to 2100. Through vulnerability and risk mapping, the objective is to gather information to support landscape planning and implement land use strategies with local stakeholders for risk management. Four contrasting scenarios are developed and exhibit contrasting trajectories of socio-economic development. Prospective scenarios are based on national and international socio-economic contexts relying on existing assessment reports. The methodological approach integrates knowledge from local stakeholders to refine each scenario during their construction and to reinforce their plausibility and relevance by accounting for local specificities, e.g. logging and pastoral activities, touristic development, urban planning, etc. A process-based model, the Forecasting Scenarios for Mountains (ForeSceM) model, developed on the Dinamica Ego modelling platform is used to spatially allocate futures LUCC for each prospective scenario. Concurrently, a spatial decision support tool, i.e. the SYLVACCESS model, is used to identify accessible areas for forestry in scenario projecting logging

  16. Applying Business Process Oriented Learning in Industry: The PROLIX Solution Approach Based on a Case Study

    Directory of Open Access Journals (Sweden)

    Dimitra Pappa


    Full Text Available With human capital being critical to corporate success, aligning individual training with business priorities, emerges as a key challenge. Business process oriented learning unites corporate training and business process management. This entails integrating learning into daily working tasks and putting in place mechanisms for the effective management of business processes, organisational roles, competencies and learning processes, to reduce the time to fill competency gaps and to build proficiency according to evolving business needs. In this paper we outline the main characteristics of the PROLIX approach for business-driven training and provide a practical example of how this concept can help a typical vehicle manufacturer effectively resolve competency related business problems stemming from changes in supply chain management.

  17. The integrative taxonomic approach applied to porifera: a case study of the homoscleromorpha. (United States)

    Boury-Esnault, Nicole; Lavrov, Dennis V; Ruiz, César A; Pérez, Thierry


    The two main scientific tasks of taxonomy are species' delineation and classification. These two tasks are often treated differently, with classification accomplished by newly-developed phylogenetic methods, often based on molecular sequences, while delimitation of species is conducted by what is often considered to be an "old-fashioned" typological approach based on morphological description. A new "integrative taxonomy" has been proposed which maintains that species delimitation should be a multidisciplinary undertaking combining several independent datasets. Here we argue that the same principle is relevant to the classification of species. In the past 20 years, we assembled various datasets based on the external morphology, anatomy, cytology, spicule shapes, geography, reproduction, genetic sequences, and metabolomics of homoscleromorph sponges. We show how we used these datasets to describe new species of homoscleromorph sponges and to elucidate their phylogenetic relationships and their phylogenetic position within the phylum Porifera.

  18. Multidisciplinary approach of early breast cancer: The biology applied to radiation oncology

    Directory of Open Access Journals (Sweden)

    Azria David


    Full Text Available Abstract Early breast cancer treatment is based on a multimodality approach with the application of clinical and histological prognostic factors to determine locoregional and systemic treatments. The entire scientific community is strongly involved in the management of this disease: radiologists for screening and early diagnosis, gynecologists, surgical oncologists and radiation oncologists for locoregional treatment, pathologists and biologists for personalized characterization, genetic counselors for BRCA mutation history and medical oncologists for systemic therapies. Recently, new biological tools have established various prognostic subsets of breast cancer and developed predictive markers for miscellaneous treatments. The aim of this article is to highlight the contribution of biological tools in the locoregional management of early breast cancer.

  19. Development of theoretical approach for describing electronic properties of hetero-interface systems under applied bias voltage (United States)

    Iida, Kenji; Noda, Masashi; Nobusada, Katsuyuki


    We have developed a theoretical approach for describing the electronic properties of hetero-interface systems under an applied electrode bias. The finite-temperature density functional theory is employed for controlling the chemical potential in their interfacial region, and thereby the electronic charge of the system is obtained. The electric field generated by the electronic charging is described as a saw-tooth-like electrostatic potential. Because of the continuum approximation of dielectrics sandwiched between electrodes, we treat dielectrics with thicknesses in a wide range from a few nanometers to more than several meters. Furthermore, the approach is implemented in our original computational program named grid-based coupled electron and electromagnetic field dynamics (GCEED), facilitating its application to nanostructures. Thus, the approach is capable of comprehensively revealing electronic structure changes in hetero-interface systems with an applied bias that are practically useful for experimental studies. We calculate the electronic structure of a SiO2-graphene-boron nitride (BN) system in which an electrode bias is applied between the graphene layer and an electrode attached on the SiO2 film. The electronic energy barrier between graphene and BN is varied with an applied bias, and the energy variation depends on the thickness of the BN film. This is because the density of states of graphene is so low that the graphene layer cannot fully screen the electric field generated by the electrodes. We have demonstrated that the electronic properties of hetero-interface systems are well controlled by the combination of the electronic charging and the generated electric field.

  20. The Langmuir isotherm: a commonly applied but misleading approach for the analysis of protein adsorption behavior. (United States)

    Latour, Robert A


    The Langmuir adsorption isotherm provides one of the simplest and most direct methods to quantify an adsorption process. Because isotherm data from protein adsorption studies often appear to be fit well by the Langmuir isotherm model, estimates of protein binding affinity have often been made from its use despite that fact that none of the conditions required for a Langmuir adsorption process may be satisfied for this type of application. The physical events that cause protein adsorption isotherms to often provide a Langmuir-shaped isotherm can be explained as being due to changes in adsorption-induced spreading, reorientation, clustering, and aggregation of the protein on a surface as a function of solution concentration in contrast to being due to a dynamic equilibrium adsorption process, which is required for Langmuir adsorption. Unless the requirements of the Langmuir adsorption process can be confirmed, fitting of the Langmuir model to protein adsorption isotherm data to obtain thermodynamic properties, such as the equilibrium constant for adsorption and adsorption free energy, may provide erroneous values that have little to do with the actual protein adsorption process, and should be avoided. In this article, a detailed analysis of the Langmuir isotherm model is presented along with a quantitative analysis of the level of error that can arise in derived parameters when the Langmuir isotherm is inappropriately applied to characterize a protein adsorption process.

  1. Kinetics-based phase change approach for VOF method applied to boiling flow (United States)

    Cifani, Paolo; Geurts, Bernard; Kuerten, Hans


    Direct numerical simulations of boiling flows are performed to better understand the interaction of boiling phenomena with turbulence. The multiphase flow is simulated by solving a single set of equations for the whole flow field according to the one-fluid formulation, using a VOF interface capturing method. Interface terms, related to surface tension, interphase mass transfer and latent heat, are added at the phase boundary. The mass transfer rate across the interface is derived from kinetic theory and subsequently coupled with the continuum representation of the flow field. The numerical model was implemented in OpenFOAM and validated against 3 cases: evaporation of a spherical uniformly heated droplet, growth of a spherical bubble in a superheated liquid and two dimensional film boiling. The computational model will be used to investigate the change in turbulence intensity in a fully developed channel flow due to interaction with boiling heat and mass transfer. In particular, we will focus on the influence of the vapor bubble volume fraction on enhancing heat and mass transfer. Furthermore, we will investigate kinetic energy spectra in order to identify the dynamics associated with the wakes of vapor bubbles. Department of Applied Mathematics, 7500 AE Enschede, NL.

  2. The ABC's of Suicide Risk Assessment: Applying a Tripartite Approach to Individual Evaluations.

    Directory of Open Access Journals (Sweden)

    Keith M Harris

    Full Text Available There is considerable need for accurate suicide risk assessment for clinical, screening, and research purposes. This study applied the tripartite affect-behavior-cognition theory, the suicidal barometer model, classical test theory, and item response theory (IRT, to develop a brief self-report measure of suicide risk that is theoretically-grounded, reliable and valid. An initial survey (n = 359 employed an iterative process to an item pool, resulting in the six-item Suicidal Affect-Behavior-Cognition Scale (SABCS. Three additional studies tested the SABCS and a highly endorsed comparison measure. Studies included two online surveys (Ns = 1007, and 713, and one prospective clinical survey (n = 72; Time 2, n = 54. Factor analyses demonstrated SABCS construct validity through unidimensionality. Internal reliability was high (α = .86-.93, split-half = .90-.94. The scale was predictive of future suicidal behaviors and suicidality (r = .68, .73, respectively, showed convergent validity, and the SABCS-4 demonstrated clinically relevant sensitivity to change. IRT analyses revealed the SABCS captured more information than the comparison measure, and better defined participants at low, moderate, and high risk. The SABCS is the first suicide risk measure to demonstrate no differential item functioning by sex, age, or ethnicity. In all comparisons, the SABCS showed incremental improvements over a highly endorsed scale through stronger predictive ability, reliability, and other properties. The SABCS is in the public domain, with this publication, and is suitable for clinical evaluations, public screening, and research.

  3. [Aquatic ecosystem modelling approach: temperature and water quality models applied to Oualidia and Nador lagoons]. (United States)

    Idrissi, J Lakhdar; Orbi, A; Hilmi, K; Zidane, F; Moncef, M


    The objective of this work is to develop an aquatic ecosystem and apply it on Moroccan lagoon systems. This model will keep us abreast of the yearly development of the main parameters that characterize these ecosystems while integrating all the data that have so far been acquired. Within this framework, a simulation model of the thermal system and a model of the water quality have been elaborated. These models, which have been simulated on the lagoon of Oualidia (North of Morocco) and validated on the lagoon of Nador (North West Mediterranean), permit to foresee the cycles of temperature of the surface and the parameters of the water quality (dissolved oxygen and biomass phytoplankton) by using meteorological information, specific features and in situ measurements in the studied sites. The elaborated model, called Zero-Dimensional, simulates the average conduct of the site during the time of variable states that are representatives of the studied ecosystem. This model will provide answers for the studied phenomena and is a work tool adequate for numerical simplicity.

  4. New approach for the study of paleofloras using geographical information systems applied to Glossopteris Flora

    Directory of Open Access Journals (Sweden)

    Isabel Cortez Christiano-de-Souza

    Full Text Available This paper introduces a methodology which makes possible the visualization of the spatial distribution of plant fossils and applies it to the occurrences of the Gondwana Floristic Province present on the eastern border of the Brazilian portion of the Paraná Basin during the Neopaleozoic. This province was chosen due to the existence of a large number of publications referring to their occurrence, so that a meta-analysis of their distribution could be based on ample information. The first step was the construction of a composite database including geographical location, geology, and the botanical systematics of each relevant fossil. The geographical locations were then georeferenced for translation into various maps showing various aspects of the distribution of the fossils. The spatial distribution of the fossil-housing outcrops shows that these are distributed along the area of deposition studied. Although some genera persisted for long periods of time, others lasted for only short intervals. As time passed, the fossil composition underwent a gradual change from the Late Carboniferous (Itararé Group to the Late Permian (Rio do Rasto Formation, with the number of genera represented decreasing from 45 in the Itararé Group to 11 in the Rio do Rasto Formation.

  5. A NURBS-based finite element model applied to geometrically nonlinear elastodynamics using a corotational approach

    KAUST Repository

    Espath, L. F R


    A numerical model to deal with nonlinear elastodynamics involving large rotations within the framework of the finite element based on NURBS (Non-Uniform Rational B-Spline) basis is presented. A comprehensive kinematical description using a corotational approach and an orthogonal tensor given by the exact polar decomposition is adopted. The state equation is written in terms of corotational variables according to the hypoelastic theory, relating the Jaumann derivative of the Cauchy stress to the Eulerian strain rate.The generalized-α method (Gα) method and Generalized Energy-Momentum Method with an additional parameter (GEMM+ξ) are employed in order to obtain a stable and controllable dissipative time-stepping scheme with algorithmic conservative properties for nonlinear dynamic analyses.The main contribution is to show that the energy-momentum conservation properties and numerical stability may be improved once a NURBS-based FEM in the spatial discretization is used. Also it is shown that high continuity can postpone the numerical instability when GEMM+ξ with consistent mass is employed; likewise, increasing the continuity class yields a decrease in the numerical dissipation. A parametric study is carried out in order to show the stability and energy budget in terms of several properties such as continuity class, spectral radius and lumped as well as consistent mass matrices.

  6. Alcohol consumption among university students: applying a social ecological approach for multi-level preventions. (United States)

    Vantamay, Somphol


    This study investigates factors affecting alcohol consumption among university students through a social ecological approach as a theoretical framework. A multistage sampling technique was used to select 1,200 university students in Bangkok, Thailand. Data were collected by a self-administered questionnaire. Descriptive statistics and multiple regression analysis at the 0.05 level of statistical significance were used to analyze the data. The results showed that all 22 independent variables can copredict alcohol consumption among university students at 41.2% (Adjusted = 40.1%). However, there were only 13 variables that affected alcohol consumption significantly: gender, age, monthly income, living arrangement, attitude toward alcohol use, perceived susceptibility of alcohol use, perceived self-efficacy, peer drinking, relatives drinking, accessibility of alcohol around university, accessibility of alcohol around community, exposure to anti-alcohol campaign, and exposure to alcohol advertising. The findings suggested that alcohol consumption was not only affected by the individual-level factor, but it was also affected by multi-level environmental factors, including interpersonal-level, institutional-level, community-level, and societal-level factors. Consequently, multi-level preventions should be urgently considered to prevent alcohol use among university students in Thailand.

  7. Applying a solution-focused approach to support a worker who is under stress. (United States)

    Mishima, Norio; Kubota, Shinya; Nagata, Shoji


    The solution-focused approach (SFA) developed by Insoo Kim Berg and Steve de Shazer at the Brief Family Therapy Center, Milwaukee, USA is classified as brief psychotherapy. We believe that SFA can give an occupational healthcare staff useful tools that will positively influence their relationships with workers, because it focuses on workers' strengths rather than their weaknesses when the staff interviews them using SFA. In this report, we explain the case of a worker who was under stress and was interviewed using SFA. Although the worker came to the interview because of his physical symptoms, he disclosed that he was under considerable stress at work and that his main concern was his relationship with his superior. One of the authors interviewed him using SFA. In the interview the worker discovered his own resources and strengths, and finally defined his goal. In the end, he discovered solutions by himself, and has been doing well in follow-up. We describe this process in detail, and discuss potential applications of SFA in occupational medicine.

  8. Personalized Medicine applied to Forensic Sciences: new advances and perspectives for a tailored forensic approach. (United States)

    Santurro, Alessandro; Vullo, Anna Maria; Borro, Marina; Gentile, Giovanna; Russa, Raffaele La; Simmaco, Maurizio; Frati, Paola; Fineschi, Vittorio


    Personalized medicine (PM), included in P5 medicine (Personalized, Predictive, Preventive, Participative and Precision medicine) is an innovative approach to the patient, emerging from the need to tailor and to fit the profile of each individual. PM promises to dramatically impact also on forensic sciences and justice system in ways we are only beginning to understand. The application of omics (genomic, transcriptomics, epigenetics/imprintomics, proteomic and metabolomics) is ever more fundamental in the so called "molecular autopsy". Emerging fields of interest in forensic pathology are represented by diagnosis and detection of predisposing conditions to fatal thromboembolic and hypertensive events, determination of genetic variants related to sudden death, such as congenital long QT syndromes, demonstration of lesions vitality, identification of biological matrices and species diagnosis of a forensic trace on crime scenes without destruction of the DNA. The aim of this paper is to describe the state-of-art in the application of personalized medicine in forensic sciences, to understand the possibilities of integration in routine investigation of these procedures with classical post-mortem studies and to underline the importance of these new updates in medical examiners' armamentarium in determining cause of death or contributing factors to death.

  9. Applying a participatory approach to the promotion of a culture of respect during childbirth. (United States)

    Ratcliffe, Hannah L; Sando, David; Mwanyika-Sando, Mary; Chalamilla, Guerino; Langer, Ana; McDonald, Kathleen P


    Disrespect and abuse (D&A) during facility-based childbirth is a topic of growing concern and attention globally. Several recent studies have sought to quantify the prevalence of D&A, however little evidence exists about effective interventions to mitigate disrespect and abuse, and promote respectful maternity care. In an accompanying article, we describe the process of selecting, implementing, and evaluating a package of interventions designed to prevent and reduce disrespect and abuse in a large urban hospital in Tanzania. Though that study was not powered to detect a definitive impact on reducing D&A, the results showed important changes in intermediate outcomes associated with this goal. In this commentary, we describe the factors that enabled this effect, especially the participatory approach we adopted to engage key stakeholders throughout the planning and implementation of the program. Based on our experience and findings, we conclude that a visible, sustained, and participatory intervention process; committed facility leadership; management support; and staff engagement throughout the project contributed to a marked change in the culture of the hospital to one that values and promotes respectful maternity care. For these changes to translate into dignified care during childbirth for all women in a sustainable fashion, institutional commitment to providing the necessary resources and staff will be needed.

  10. New modelling method for fast reactor neutronic behaviours analysis; Nouvelles methodes de modelisation neutronique des reacteurs rapides de quatrieme Generation

    Energy Technology Data Exchange (ETDEWEB)

    Jacquet, P.


    Due to safety rules running on fourth generation reactors' core development, neutronics simulation tools have to be as accurate as never before. First part of this report enumerates every step of fast reactor's neutronics simulation implemented in current reference code: ECCO. Considering the field of fast reactors that meet criteria of fourth generation, ability of models to describe self-shielding phenomenon, to simulate neutrons leakage in a lattice of fuel assemblies and to produce representative macroscopic sections is evaluated. The second part of this thesis is dedicated to the simulation of fast reactors' core with steel reflector. These require the development of advanced methods of condensation and homogenization. Several methods are proposed and compared on a typical case: the ZONA2B core of MASURCA reactor. (author) [French] Les criteres de surete qui regissent le developpement de coeurs de reacteurs de quatrieme generation implique l'usage d'outils de calcul neutronique performants. Une premiere partie de la these reprend toutes les etapes de modelisation neutronique des reacteurs rapides actuellement d'usage dans le code de reference ECCO. La capacite des modeles a decrire le phenomene d'autoprotection, a representer les fuites neutroniques au niveau d'un reseau d'assemblages combustibles et a generer des sections macroscopiques representatives est appreciee sur le domaine des reacteurs rapides innovants respectant les criteres de quatrieme generation. La deuxieme partie de ce memoire se consacre a la modelisation des coeurs rapides avec reflecteur acier. Ces derniers necessitent le developpement de methodes avancees de condensation et d'homogenisation. Plusieurs methodes sont proposees et confrontees sur un probleme de modelisation typique: le coeur ZONA2B du reacteur maquette MASURCA

  11. Bioremediation Approaches in a Laboratory Activity for the Industrial Biotechnology and Applied Microbiology (IBAM Course

    Directory of Open Access Journals (Sweden)

    L. Raiger Iustman


    Full Text Available Industrial Biotechnology and Applied Microbiology is an optional 128h-course for Chemistry and Biology students at the Faculty of Sciences, University of Buenos Aires, Argentina. This course is usually attended by 25 students, working in teams of two. The curriculum, with 8 lab exercises, includes an oil bioremediation practice covering an insight of bioremediation processes: the influence of pollutants on autochthonous microbiota, biodegrader isolation and biosurfactant production for bioavailability understanding. The experimental steps are: (A evaluation of microbial tolerance to pollutants by constructing pristine soil microcosms contaminated with diesel or xylene and (B isolation of degraders and biosurfactant production analysis. To check microbial tolerance, microcosms are incubated during one week at 25-28ºC. Samples are collected at 0, 4 and every 48 h for CFU/g soil testing. An initial decrease of total CFU/g related to toxicity is noticed. At the end of the experiment, a recovery of the CFU number is observed, evidencing enrichment in biodegraders. Some colonies from the CFU counting plates are streaked in M9-agar with diesel as sole carbon source. After a week, isolates are inoculated on M9-Broth supplemented with diesel to induce biosurfactant production. Surface tension and Emulsification Index are measured in culture supernatants to visualize tensioactive effect of bacterial products. Besides the improvement in the good microbiological practices, the students show enthusiasm in different aspects, depending on their own interests. While biology students explore and learn new concepts on solubility, emulsions and bioavailability, chemistry students show curiosity in bacterial behavior and manipulation of microorganisms for environmental benefits.

  12. Developing and applying a GIS-assisted approach to locating wind farms in the UK

    Energy Technology Data Exchange (ETDEWEB)

    Baban, Serwan M.J. [West Indies Univ., Dept. of Surveying and Land Information, St Augustine, Trinidad (Trinidad and Tobago); Parry, Tim [Coventry Univ., School of Natural and Environmental Sciences, Coventry (United Kingdom)


    An increase in public awareness regarding the negative impact of traditional power-generating methods, especially coal and oil-fired power stations, on the environment has created a demand for developing and using environmentally friendly renewable energy. Wind power is a popular and safe form of renewable energy. It can be economically viable, does not produce any physical pollution and can contribute radically to the reduction in air pollution. In the UK, the demand for wind energy is mounting. However, achieving the goal set by the EU will require a substantial expansion. Planning and environmental restrictions and conflicts would inevitably accompany this growth. A questionnaire targeting relevant public and private sectors in the UK has revealed the lack of coherent national criteria for locating wind farms. Using information from the questionnaire and the available published literature, simple Geographical Information System (GIS)-assisted wind farm location criteria were developed for the UK. A GIS (IDRISI) was employed to apply these criteria using two different methods to combine information layers for a site in Lancashire. The first considered all the layers as being equally important and gave them equal weight. The second grouped the layers and graded them according to perceived importance. The outputs were composed of classes from 0 to 10, where 0 represents ideal locations and 10 represents unsuitable locations. Using the second method has resulted in a slight increase in the geographical extent for the most suitable sites. These maps can be used to assist in the decision-making process when locating wind farm sites. (Author)

  13. Moderate Growth Time Series for Dynamic Combinatorics Modelisation

    CERN Document Server

    Jaff, Luaï; Kacem, Hatem Hadj; Bertelle, Cyrille


    Here, we present a family of time series with a simple growth constraint. This family can be the basis of a model to apply to emerging computation in business and micro-economy where global functions can be expressed from local rules. We explicit a double statistics on these series which allows to establish a one-to-one correspondence between three other ballot-like strunctures.

  14. Qualified Presumption of Safety (QPS) is a generic risk assessment approach applied by the European Food Safety Authority (EFSA)

    DEFF Research Database (Denmark)

    Leuschner, R. G. K.; Robinson, T. P.; Hugas, M.;


    Qualified Presumption of Safety (QPS) is a generic risk assessment approach applied by the European Food Safety Authority (EFSA) to notified biological agents aiming at simplifying risk assessments across different scientific Panels and Units. The aim of this review is to outline the implementation...... and value of the QPS assessment for EFSA and to explain its principles such as the unambiguous identity of a taxonomic unit, the body of knowledge including potential safety concerns and how these considerations lead to a list of biological agents recommended for QPS which EFSA keeps updated through...

  15. Applying the institutional review board data repository approach to manage ethical considerations in evaluating and studying medical education

    Directory of Open Access Journals (Sweden)

    Erin K. Thayer


    Full Text Available Issue: Medical educators and educational researchers continue to improve their processes for managing medical student and program evaluation data using sound ethical principles. This is becoming even more important as curricular innovations are occurring across undergraduate and graduate medical education. Dissemination of findings from this work is critical, and peer-reviewed journals often require an institutional review board (IRB determination. Approach: IRB data repositories, originally designed for the longitudinal study of biological specimens, can be applied to medical education research. The benefits of such an approach include obtaining expedited review for multiple related studies within a single IRB application and allowing for more flexibility when conducting complex longitudinal studies involving large datasets from multiple data sources and/or institutions. In this paper, we inform educators and educational researchers on our analysis of the use of the IRB data repository approach to manage ethical considerations as part of best practices for amassing, pooling, and sharing data for educational research, evaluation, and improvement purposes. Implications: Fostering multi-institutional studies while following sound ethical principles in the study of medical education is needed, and the IRB data repository approach has many benefits, especially for longitudinal assessment of complex multi-site data.

  16. Augmented design and analysis of computer experiments: a novel tolerance embedded global optimization approach applied to SWIR hyperspectral illumination design. (United States)

    Keresztes, Janos C; John Koshel, R; D'huys, Karlien; De Ketelaere, Bart; Audenaert, Jan; Goos, Peter; Saeys, Wouter


    A novel meta-heuristic approach for minimizing nonlinear constrained problems is proposed, which offers tolerance information during the search for the global optimum. The method is based on the concept of design and analysis of computer experiments combined with a novel two phase design augmentation (DACEDA), which models the entire merit space using a Gaussian process, with iteratively increased resolution around the optimum. The algorithm is introduced through a series of cases studies with increasing complexity for optimizing uniformity of a short-wave infrared (SWIR) hyperspectral imaging (HSI) illumination system (IS). The method is first demonstrated for a two-dimensional problem consisting of the positioning of analytical isotropic point sources. The method is further applied to two-dimensional (2D) and five-dimensional (5D) SWIR HSI IS versions using close- and far-field measured source models applied within the non-sequential ray-tracing software FRED, including inherent stochastic noise. The proposed method is compared to other heuristic approaches such as simplex and simulated annealing (SA). It is shown that DACEDA converges towards a minimum with 1 % improvement compared to simplex and SA, and more importantly requiring only half the number of simulations. Finally, a concurrent tolerance analysis is done within DACEDA for to the five-dimensional case such that further simulations are not required.

  17. Automatic spline-smoothing approach applied to denoise Moroccan resistivity data phosphate deposit “disturbances” map

    Directory of Open Access Journals (Sweden)

    Saad Bakkali


    Full Text Available This paper focuses on presenting a method which is able to filter out noise and suppress outliers of sampled real functions under fairly general conditions. The automatic optimal spline-smoothing approach automatically determi-nes how a cubic spline should be adjusted in a least-squares optimal sense from an a priori selection of the number of points defining an adjusting spline, but not their location on that curve. The method is fast and easily allowed for selecting several knots, thereby adding desirable flexibility to the procedure. As an illustration, we apply the AOSSA method to Moroccan resistivity data phosphate deposit “disturbances” map. The AOSSA smoothing method is an e-fficient tool in interpreting geophysical potential field data which is particularly suitable in denoising, filtering and a-nalysing resistivity data singularities. The AOSSA smoothing and filtering approach was found to be consistently use-ful when applied to modeling surface phosphate “disturbances.”.

  18. Making good theory practical: five lessons for an Applied Social Identity Approach to challenges of organizational, health, and clinical psychology. (United States)

    Haslam, S Alexander


    Social identity research was pioneered as a distinctive theoretical approach to the analysis of intergroup relations but over the last two decades it has increasingly been used to shed light on applied issues. One early application of insights from social identity and self-categorization theories was to the organizational domain (with a particular focus on leadership), but more recently there has been a surge of interest in applications to the realm of health and clinical topics. This article charts the development of this Applied Social Identity Approach, and abstracts five core lessons from the research that has taken this forward. (1) Groups and social identities matter because they have a critical role to play in organizational and health outcomes. (2) Self-categorizations matter because it is people's self-understandings in a given context that shape their psychology and behaviour. (3) The power of groups is unlocked by working with social identities not across or against them. (4) Social identities need to be made to matter in deed not just in word. (5) Psychological intervention is always political because it always involves some form of social identity management. Programmes that seek to incorporate these principles are reviewed and important challenges and opportunities for the future are identified.

  19. Biological Rhythms Modelisation of Vigilance and Sleep in Microgravity State with COSINOR and Volterra's Kernels Methods (United States)

    Gaudeua de Gerlicz, C.; Golding, J. G.; Bobola, Ph.; Moutarde, C.; Naji, S.


    The spaceflight under microgravity cause basically biological and physiological imbalance in human being. Lot of study has been yet release on this topic especially about sleep disturbances and on the circadian rhythms (alternation vigilance-sleep, body, temperature...). Factors like space motion sickness, noise, or excitement can cause severe sleep disturbances. For a stay of longer than four months in space, gradual increases in the planned duration of sleep were reported. [1] The average sleep in orbit was more than 1.5 hours shorter than the during control periods on earth, where sleep averaged 7.9 hours. [2] Alertness and calmness were unregistered yield clear circadian pattern of 24h but with a phase delay of 4h.The calmness showed a biphasic component (12h) mean sleep duration was 6.4 structured by 3-5 non REM/REM cycles. Modelisations of neurophysiologic mechanisms of stress and interactions between various physiological and psychological variables of rhythms have can be yet release with the COSINOR method. [3

  20. Modelisation of strains measured by X-ray diffraction in composites with spherical particles

    Energy Technology Data Exchange (ETDEWEB)

    Durand, L.; Lavelle, B.; Drira-Halouani, R.; Altibelli, A. [CNRS, Toulouse (France). CEMES


    In a particle composite, elaboration residual stresses have two main origins : differences between thermal expansion coefficients of particles and matrix on the one hand, and volume changes induced by reactions at particles / matrix interface on the other hand. We have compared calculated thermal stresses, and experimental measures on two composites, one presenting an interface reactivity and the other none. The two composites with a nickel matrix and spherical particles either of silica or of alumina have been sintered at 1400 C and analyzed between room temperature and 240 C by X-ray diffraction (Cu K{alpha} radiation). In the semi-infinite composite model, spherical particles have been distributed at the points of a simple cubic lattice. Modelised thickness is larger in comparison of the thickness analyzed by X-ray diffraction. Calculations are based on elastic theory and the difference of coefficients of thermal expansion between the matrix and the particles. Materials are supposed isotropic. At a given temperature, the strain to be observed by X-ray diffraction in a given directions calculated from the distribution of strains in matrix; absorption phenomena are taken into account. Effects of the free surface and of interfacial reactivity are thus shown off. (orig.)

  1. Integrated Case-Based Applied Pathology (ICAP): a diagnostic-approach model for the learning and teaching of veterinary pathology. (United States)

    Krockenberger, Mark B; Bosward, Katrina L; Canfield, Paul J


    Integrative Case-Based Applied Pathology (ICAP) cases form one component of learning and understanding the role of pathology in the veterinary diagnostic process at the Faculty of Veterinary Science, University of Sydney. It is a strategy that focuses on student-centered learning in a problem-solving context in the year 3 curriculum. Learning exercises use real case material and are primarily delivered online, providing flexibility for students with differing learning needs, who are supported by online, peer, and tutor support. The strategy relies heavily on the integration of pre-clinical and para-clinical information with the introduction of clinical material for the purposes of a logical three-level, problem-oriented approach to the diagnosis of disease. The focus is on logical diagnostic problem solving, primarily using gross pathology and histopathological material, with the inclusion of microbiological, parasitological, and clinical pathological data. The ICAP approach is linked to and congruent with the problem-oriented approach adopted in veterinary medicine and the case-based format used by one of the authors (PJC) for the teaching and learning of veterinary clinical pathology in year 4. Additionally, final-year students have the opportunity, during a diagnostic pathology rotation, to assist in the development and refinement of further ICAPs, which reinforces the importance of pathology in the veterinary diagnostic process. Evidence of the impact of the ICAP approach, based primarily on student surveys and staff peer feedback collected over five years, shows that discipline-specific learning, vertical and horizontal integration, alignment of learning outcomes and assessment, and both veterinary and generic graduate attributes were enhanced. Areas for improvement were identified in the approach, most specifically related to assistance in the development of generic teamwork skills.

  2. Applying the Ecosystem Approach to Select Priority Areas for Forest Landscape Restoration in the Yungas, Northwestern Argentina (United States)

    Ianni, Elena; Geneletti, Davide


    This paper proposes a method to select forest restoration priority areas consistently with the key principles of the Ecosystem Approach (EA) and the Forest Landscape Restoration (FLR) framework. The methodology is based on the principles shared by the two approaches: acting at ecosystem scale, involving stakeholders, and evaluating alternatives. It proposes the involvement of social actors which have a stake in forest management through multicriteria analysis sessions aimed at identifying the most suitable forest restoration intervention. The method was applied to a study area in the native forests of Northern Argentina (the Yungas). Stakeholders were asked to identify alternative restoration actions, i.e. potential areas implementing FLR. Ten alternative fincas—estates derived from the Spanish land tenure system—differing in relation to ownership, management, land use, land tenure, and size were evaluated. Twenty criteria were selected and classified into four groups: biophysical, social, economic and political. Finca Ledesma was the closest to the economic, social, environmental and political goals, according to the values and views of the actors involved in the decision. This study represented the first attempt to apply EA principles to forest restoration at landscape scale in the Yungas region. The benefits obtained by the application of the method were twofold: on one hand, researchers and local actors were forced to conceive the Yungas as a complex net of rights rather than as a sum of personal interests. On the other hand, the participatory multicriteria approach provided a structured process for collective decision-making in an area where it has never been implemented.

  3. Exploring Flexible and Multidisciplinary Approaches to Applied Science Research Project Assessments: Case Studies from the NASA DEVELOP National Program (United States)

    Crepps, G.; Childs-Gleason, L. M.; Favors, J. E.; Ross, K. W.; Rogers, L.; Allsbrook, K. N.; Ruiz, M. L.


    Within the NASA DEVELOP National Program, teams conduct rapid prototype and feasibility projects, applying NASA Earth Observations to a broad range of problems in diverse focus areas, including water resources, agriculture, disaster management, and ecological forecasting, with the goal of assisting partner organizations in their decision making processes. Projects vary in scope, design, and satellite data utilized. As a result, there is no "fixed" set of indicators that encompasses all relevant impacts of all projects. Rather, a flexible toolkit of both shared indicators and individualized approaches is needed to capture the diverse outcomes of these projects, while still allowing for comparability of the projects. This has been done through the creation of pre- and post-project partner assessments that capture partner needs, capabilities, and expectations. This provides both baseline data and an overview of project impacts on partners. Selected projects are then individually assessed in greater detail through partner follow-ups and research into the quantification of project impacts utilizing interdisciplinary approaches to fit each project. This process is discussed through three examples of project impact assessments that draw from varied discipline approaches including cost benefit analysis and ecosystem services.

  4. Applying a developmental approach to quality of life assessment in children and adolescents with psychological disorders: challenges and guidelines. (United States)

    Carona, Carlos; Silva, Neuza; Moreira, Helena


    Research on the quality of life (QL) of children/adolescents with psychological disorders has flourished over the last few decades. Given the developmental challenges of QL measurements in pediatric populations, the aim of this study was to ascertain the extent to which a developmental approach to QL assessment has been applied to pedopsychiatric QL research. A systematic literature search was conducted in three electronic databases (PubMed, PsycINFO, SocINDEX) from 1994 to May 2014. Quantitative studies were included if they assessed the self- or proxy-reported QL of children/adolescents with a psychological disorder. Data were extracted for study design, participants, QL instruments and informants, and statistical approach to age-related specificities. The systematic review revealed widespread utilization of developmentally appropriate QL instruments but less frequent use of both self and proxy reports and an inconsistent approach to age group specificities. Methodological guidelines are discussed to improve the developmental validity of QL research for children/adolescents with mental disorders.

  5. An up-close look at Urban Regeneration. Cultural approaches and applied strategies for the rebirth of cities

    Directory of Open Access Journals (Sweden)

    Eliana Cangelli


    Full Text Available The term Regeneration defines new approaches to the transformation of cities, designed in such a way to move beyond traditional urban-restoration efforts centred around large-scale plans by proposing minimal, non-invasive initiatives that stress listening to the citizenry while bringing to bear creative capabilities and a knowledge of the new-generation technology that has taken on strategic importance when it comes to the development of urban areas. Emphasising an ethical awareness that the city constitutes a shared resource, and that any transformations it undergoes must meet the needs of the public as a whole, endowing the local territory with a strong core structure but a light architecture, is one promising approach to actual renewal efforts. In examining the characteristics of Italian cities, the author focuses on the potential for establishing an environmental balance of the urban metabolism through work on outlying areas, describing the technical and scientific contribution made to date by Technological and Environmental Planning and Design while identifying project design and planning as the path to be taken to arrive at applied assessment and confirmation of the hypothetical approaches explored.

  6. Numerical modelling of Charpy-V notch test by local approach to fracture. Application to an A508 steel in the ductile-brittle transition range; Modelisation de l'essai Charpy par l'approche locale de la rupture. Application au cas de l'acier 16MND5 dans le domaine de transition

    Energy Technology Data Exchange (ETDEWEB)

    Tanguy, B


    Ferritic steels present a transition of the rupture mode which goes progressively of a brittle rupture (cleavage) to a ductile rupture when the temperature increases. The following of the difference of the transition temperature of the PWR vessel steel by the establishment of toughness curves makes of the Charpy test an integrating part of the monitoring of the French PWR reactors. In spite of the advantages which are adapted to it in particular its cost, the Charpy test does not allow to obtain directly a variable which characterizes a crack propagation resistance as for instance the toughness used for qualifying the mechanical integrity of a structure. This work deals with the establishment of the through impact strength-toughness in the transition range of the vessel steel: 16MND5 from a non-empirical approach based on the local approach of the rupture. The brittle rupture is described by the Beremin model (1983), which allows to describe the dispersion inherent in this rupture mode. The description of the brittle fissure is carried out by the GTN model (1984) and by the Rousselier model (1986). This last model has been modified in order to obtain a realistic description of the brittle damage in the case of fast solicitations and of local heating. The method proposed to determine the parameters of the damage models depends only of tests on notched specimens and of the inclusion data of the material. The behaviour is described by an original formulation parametrized in temperature which allows to describe all the tests carried out in this study. Before using this methodology, an experimental study of the behaviour and of the rupture modes of the steel 16MND5 has been carried out. From the toughness tests carried out in quasi-static and dynamical conditions, it has been revealed that this steel does not present important unwedging of its toughness curve due to the velocity effect. In the transition range, local heating of about 150 C have been measured in the root

  7. Modeling temperature and moisture fields in conditioned spaces using zonal approach, including sorption phenomena in buildings materials; Modelisation thermo-hydro-aeraulique des locaux climatises selon l'approche zonale (prise en compte des phenomenes de sorption d'humidite)

    Energy Technology Data Exchange (ETDEWEB)

    Cordeiro Mendoca, K.


    Building simulation models represent in our days an important tool for building conception and performance analysis. Although moisture interacts in many ways with the whole building affecting therefore its behavior, frequently these models neglects the interactions between them. In addition, in most of them, indoor air conditions are considered uniform, which is a non-realistic assumption in conditioned spaces. In this work, a model to predict temperature and moisture fields in conditioned spaces, using zonal approach, is proposed. This method is based in dividing spatially a room in a relative small number of zones, typically on the order of tens to hundreds, where the state variables of air are considered uniform, with the exception of pressure that varies hydrostatically. While not as fine-grained as CFD simulation, zonal models do give useful information about temperature and moisture distributions that is important in comfort analysis. The proposed model was structured in three groups of sub-models representing the three building domains: indoor air, envelope and HVAC system. The indoor air sub-model is related to the indoor air space, where airflow speed can be considered weak. The envelope sub-model is related to the radiation exchanges between envelope and its neighborhood, and to the simultaneous heat and mass transfers across the envelope material. This latest can be represented by four sub-models of different complexity levels, with two of them taking into account moisture adsorption and desorption by building materials. Concerning to the HVAC system model, it refers to the whole system that means equipment, control and specific airflow from equipment. All sub-models were coupled into a modular simulation environment, SPARK, well-adapted to compare different models. The applicability of the proposed model is shown by two examples. The first one shows the importance of considering moisture sorption phenomena in the prediction of indoor air conditions

  8. Workspace design for crane cabins applying a combined traditional approach and the Taguchi method for design of experiments. (United States)

    Spasojević Brkić, Vesna K; Veljković, Zorica A; Golubović, Tamara; Brkić, Aleksandar Dj; Kosić Šotić, Ivana


    Procedures in the development process of crane cabins are arbitrary and subjective. Since approximately 42% of incidents in the construction industry are linked to them, there is a need to collect fresh anthropometric data and provide additional recommendations for design. In this paper, dimensioning of the crane cabin interior space was carried out using a sample of 64 crane operators' anthropometric measurements, in the Republic of Serbia, by measuring workspace with 10 parameters using nine measured anthropometric data from each crane operator. This paper applies experiments run via full factorial designs using a combined traditional and Taguchi approach. The experiments indicated which design parameters are influenced by which anthropometric measurements and to what degree. The results are expected to be of use for crane cabin designers and should assist them to design a cabin that may lead to less strenuous sitting postures and fatigue for operators, thus improving safety and accident prevention.

  9. Methodology to characterize a residential building stock using a bottom-up approach: a case study applied to Belgium

    Directory of Open Access Journals (Sweden)

    Samuel Gendebien


    Full Text Available In the last ten years, the development and implementation of measures to mitigate climate change have become of major importance. In Europe, the residential sector accounts for 27% of the final energy consumption [1], and therefore contributes significantly to CO2 emissions. Roadmaps towards energy-efficient buildings have been proposed [2]. In such a context, the detailed characterization of residential building stocks in terms of age, type of construction, insulation level, energy vector, and of evolution prospects appears to be a useful contribution to the assessment of the impact of implementation of energy policies. In this work, a methodology to develop a tree-structure characterizing a residential building stock is presented in the frame of a bottom-up approach that aims to model and simulate domestic energy use. The methodology is applied to the Belgian case for the current situation and up to 2030 horizon. The potential applications of the developed tool are outlined.

  10. On finding the C in CBT: the challenges of applying gambling-related cognitive approaches to video-gaming. (United States)

    Delfabbro, Paul; King, Daniel


    Many similarities have been drawn between the activities of gambling and video-gaming. Both are repetitive activities with intermittent reinforcement, decision-making opportunities, and elements of risk-taking. As a result, it might be tempting to believe that cognitive strategies that are used to treat problem gambling might also be applied to problematic video gaming. In this paper, we argue that many cognitive approaches to gambling that typically involve a focus on erroneous beliefs about probabilities and randomness are not readily applicable to video gaming. Instead, we encourage a focus on other clusters of cognitions that relate to: (a) the salience and over-valuing of gaming rewards, experiences, and identities, (b) maladaptive and inflexible rules about behaviour, (c) the use of video-gaming to maintain self-esteem, and (d) video-gaming for social status and recognition. This theoretical discussion is advanced as a starting point for the development of more refined cognitive treatment approaches for problematic video gaming.

  11. Applying a learning design methodology in the flipped classroom approach – empowering teachers to reflect and design for learning

    Directory of Open Access Journals (Sweden)

    Evangelia Triantafyllou


    Full Text Available One of the recent developments in teaching that heavily relies on current technology is the “flipped classroom” approach. In a flipped classroom the traditional lecture and homework sessions are inverted. Students are provided with online material in order to gain necessary knowledge before class, while class time is devoted to clarifications and application of this knowledge. The hypothesis is that there could be deep and creative discussions when teacher and students physically meet. This paper discusses how the learning design methodology can be applied to represent, share and guide educators through flipped classroom designs. In order to discuss the opportunities arising by this approach, the different components of the Learning Design – Conceptual Map (LD-CM are presented and examined in the context of the flipped classroom. It is shown that viewing the flipped classroom through the lens of learning design can promote the use of theories and methods to evaluate its effect on the achievement of learning objectives, and that it may draw attention to the employment of methods to gather learner responses. Moreover, a learning design approach can enforce the detailed description of activities, tools and resources used in specific flipped classroom models, and it can make educators more aware of the decisions that have to be taken and people who have to be involved when designing a flipped classroom. By using the LD-CM, this paper also draws attention to the importance of characteristics and values of different stakeholders (i.e. institutions, educators, learners, and external agents, which influence the design and success of flipped classrooms. Moreover, it looks at the teaching cycle from a flipped instruction model perspective and adjusts it to cater for the reflection loops educators are involved when designing, implementing and re-designing a flipped classroom. Finally, it highlights the effect of learning design on the guidance

  12. A comparison of a modified sequential oral sensory approach to an applied behavior-analytic approach in the treatment of food selectivity in children with autism spectrum disorder. (United States)

    Peterson, Kathryn M; Piazza, Cathleen C; Volkert, Valerie M


    Treatments of pediatric feeding disorders based on applied behavior analysis (ABA) have the most empirical support in the research literature (Volkert & Piazza, 2012); however, professionals often recommend, and caregivers often use, treatments that have limited empirical support. In the current investigation, we compared a modified sequential oral sensory approach (M-SOS; Benson, Parke, Gannon, & Muñoz, 2013) to an ABA approach for the treatment of the food selectivity of 6 children with autism. We randomly assigned 3 children to ABA and 3 children to M-SOS and compared the effects of treatment in a multiple baseline design across novel, healthy target foods. We used a multielement design to assess treatment generalization. Consumption of target foods increased for children who received ABA, but not for children who received M-SOS. We subsequently implemented ABA with the children for whom M-SOS was not effective and observed a potential treatment generalization effect during ABA when M-SOS preceded ABA.

  13. An analysis-synthesis approach for neurosphere modelisation under phase-contrast microscopy. (United States)

    Rigaud, Stéphane; Huang, Chao-Hui; Ahmed, Sohail; Lim, Joo-Hwee; Racoceanu, Daniel


    The study of stem cells is one of the most important biomedical research. Understanding their development could allow multiple applications in regenerative medicine. For this purpose, automated solutions for the observation of stem cell development process are needed. This study introduces an on-line analysis method for the modelling of neurosphere evolution during the early time of their development under phase contrast microscopy. From the corresponding phase contrast time-lapse sequences, we extract information from the neurosphere using a combination of phase contrast physics deconvolution and curve detection for locate the cells inside the neurosphere. Then, based on prior biological knowledge, we generate possible and optimal 3-dimensional configuration using 2D to 3D registration methods and evolutionary optimisation algorithm.

  14. Applying Cognitive Interviewing to Inform Measurement of Partnership Readiness: A New Approach to Strengthening Community-Academic Research (United States)

    Teal, Randall; Enga, Zoe; Diehl, Sandra J.; Rohweder, Catherine L.; Kim, Mimi; Dave, Gaurav; Durr, April; Wynn, Mysha; Isler, Malika Roman; Corbie-Smith, Giselle; Weiner, Bryan J.


    Background Partnerships between academic and community-based organizations can richly inform the research process and speed translation of findings. While immense potential exists to co-conduct research, a better understanding of how to create and sustain equitable relationships between entities with different organizational goals, structures, resources, and expectations is needed. Objective To engage community leaders in the development of an instrument to assess community-based organizations' interest and capacity to engage with academia in translational research partnerships. Methods Leaders from community-based organizations partnered with our research team in the design of a 50-item instrument to assess organizational experience with applying for federal funding and conducting research studies. Respondents completed a self-administered, paper/pencil survey and a follow-up structured cognitive interview (n=11). A community advisory board (n=8) provided further feedback on the survey through guided discussion. Thematic analysis of the cognitive interviews and a summary of the community advisory board discussion informed survey revisions. Results Cognitive interviews and discussion with community leaders identified language and measurement issues for revision. Importantly, they also revealed an unconscious bias on the part of researchers and offered an opportunity, at an early research stage, to address imbalances in the survey perspective and to develop a more collaborative, equitable approach. Conclusions Engaging community leaders enhanced face and content validity and served as a means to form relationships with potential community co-investigators in the future. Cognitive interviewing can enable a bi-directional approach to partnerships, starting with instrument development. PMID:26639377

  15. The magnitude of events following a strong earthquake: and a pattern recognition approach applied to Italian seismicity (United States)

    Gentili, Stefania; Di Giovambattista, Rita


    In this study, we propose an analysis of the earthquake clusters occurred in Italy from 1980 to 2015. In particular, given a strong earthquake, we are interested to identify statistical clues to forecast whether a subsequent strong earthquake will follow. We apply a pattern recognition approach to verify the possible precursors of a following strong earthquake. Part of the analysis is based on the observation of the cluster during the first hours/days after the first large event. The features adopted are, among the others, the number of earthquakes, the radiated energy and the equivalent source area. The other part of the analysis is based on the characteristics of the first strong earthquake, like its magnitude, depth, focal mechanism, the tectonic position of the source zone. The location of the cluster inside the Italia territory is of particular interest. In order to characterize the precursors depending on the cluster type, we used decision trees as classifiers on single precursor separately. The performances of the classification are tested by leave-one-out method. The analysis is done using different time-spans after the first strong earthquake, in order to simulate the increase of information available as time passes during the seismic clusters. The performances are assessed in terms of precision, recall and goodness of the single classifiers and the ROC graph is shown.

  16. Applying a Markov approach as a Lean Thinking analysis of waste elimination in a Rice Production Process

    Directory of Open Access Journals (Sweden)

    Eldon Glen Caldwell Marin


    Full Text Available The Markov Chains Model was proposed to analyze stochastic events when recursive cycles occur; for example, when rework in a continuous flow production affects the overall performance. Typically, the analysis of rework and scrap is done through a wasted material cost perspective and not from the perspective of waste capacity that reduces throughput and economic value added (EVA. Also, we can not find many cases of this application in agro-industrial production in Latin America, given the complexity of the calculations and the need for robust applications. This scientific work presents the results of a quasi-experimental research approach in order to explain how to apply DOE methods and Markov analysis in a rice production process located in Central America, evaluating the global effects of a single reduction in rework and scrap in a part of the whole line. The results show that in this case it is possible to evaluate benefits from Global Throughput and EVA perspective and not only from the saving costs perspective, finding a relationship between operational indicators and corporate performance. However, it was found that it is necessary to analyze the markov chains configuration with many rework points, also it is still relevant to take into account the effects on takt time and not only scrap´s costs.

  17. The effects of music therapy incorporated with applied behavior analysis verbal behavior approach for children with autism spectrum disorders. (United States)

    Lim, Hayoung A; Draper, Ellary


    This study compared a common form of Applied Behavior Analysis Verbal Behavior (ABA VB) approach and music incorporated with ABA VB method as part of developmental speech-language training in the speech production of children with Autism Spectrum Disorders (ASD). This study explored how the perception of musical patterns incorporated in ABA VB operants impacted the production of speech in children with ASD. Participants were 22 children with ASD, age range 3 to 5 years, who were verbal or pre verbal with presence of immediate echolalia. They were randomly assigned a set of target words for each of the 3 training conditions: (a) music incorporated ABA VB, (b) speech (ABA VB) and (c) no-training. Results showed both music and speech trainings were effective for production of the four ABA verbal operants; however, the difference between music and speech training was not statistically different. Results also indicated that music incorporated ABA VB training was most effective in echoic production, and speech training was most effective in tact production. Music can be incorporated into the ABA VB training method, and musical stimuli can be used as successfully as ABA VB speech training to enhance the functional verbal production in children with ASD.

  18. An Overview of Modeling Approaches Applied to Aggregation-Based Fleet Management and Integration of Plug-in Electric Vehicles †

    DEFF Research Database (Denmark)

    You, Shi; Hu, Junjie; Ziras, Charalampos


    and systems are seen as useful tools to support the related studies for different stakeholders in a tangible way. This paper presents an overview of modeling approaches applied to support aggregation-based management and integration of PEVs from the perspective of fleet operators and grid operators......, respectively. We start by explaining a structured modeling approach, i.e., a flexible combination of process models and system models, applied to different management and integration studies. A state-of-the-art overview of modeling approaches applied to represent several key processes, such as charging...... management, and key systems, such as the PEV fleet, is then presented, along with a detailed description of different approaches. Finally, we discuss several considerations that need to be well understood during the modeling process in order to assist modelers and model users in the appropriate decisions...

  19. Modelisation of the contribution of the Na/Ca exchanger to cell membrane potential and intracellular ion concentrations. (United States)

    Bahlouli, S; Hamdache, F; Riane, H


    Modelisation plays a significant role in the study of ion transfer through the cell membrane and in the comprehension of cellular excitability. We were interested in the selective ion transfers through the K(Ca), Na(v), Ca(v) channels and the Na/Ca exchanger (NCX). The membrane behaves like an electric circuit because of the existence of ion gradients maintained by the cell. The non-linearity of this circuit gives rise to complex oscillations of the membrane potential. By application of the finite difference method (FDM) and the concept of percolation we studied the role of the NCX in the regulation of the intracellular Ca(2+) concentration and the oscillations of the membrane potential. The fractal representation of the distribution of active channels allows us to follow the diffusion of intracellular Ca(2+) ions. These calculations show that the hyperpolarization and the change in the burst duration of the membrane potential are primarily due to the NCX.


    Directory of Open Access Journals (Sweden)

    J. K.S. NASCIMENTO et al


    Full Text Available Teaching biochemistry in higher education is increasingly becoming a challenge. It is notoriously difficult for students to assimilate the topic; in addition there are many complaints about the complexity of subjects and a lack of integration with the day-to-day. A recurrent problem in undergraduate courses is the absence of teaching practice in specific disciplines. This work aimed to stimulate students in the biological sciences course who were enrolled in the discipline of MOLECULAR DIVERSITY (MD, to create hypothetical classes focused on basic education highlighting the proteins topic. The methodology was applied in a class that contained 35 students. Seven groups were formed, and each group chose a protein to be used as a source of study for elementary school classes. A lesson plan was created focusing on the methodology that the group would use to manage a class. The class was to be presented orally. Students were induced to be creative and incorporate a teacher figure, and to propose teaching methodologies for research using the CTS approach (Science, Technology and Society. Each group presented a three-dimensional structure of the protein they had chosen, explained their structural features and functions and how they would develop the theme for a class of basic education, and what kind of methodology they would use for this purpose. At the end of the presentations, a questionnaire was given to students in order to evaluate the effectiveness of the methodology in the teaching-learning process. The activity improved the teacher’s training and developed skills and abilities, such as creativity, didactical planning, teaching ability, development of educational models and the use of new technologies. The methodology used in this work was extremely important to the training of future teachers, who were able to better understand the content covered in the discipline and relate it to day-to-day life.

  1. Modelisation de la synthese reactive de poudres ultrafines dans un reacteur a plasma thermique (United States)

    Desilets, Martin

    La presente these s'inscrit dans le cadre de la modelisation mathematique des ecoulements a plasmas thermiques inertes et reactifs. Elle vise plus precisement a combler les lacunes des modeles existants en portant une attention particuliere aux phenomenes de transport multicomposant et a la prediction des transformations chimiques. Pour repondre a ces attentes et ainsi poursuivre le developpement dans ce domaine, un modele global a ete developpe. Il combine la resolution d'equations conservatives pour la masse, l'energie et le momentum. La generation d'un plasma inductif (h.f ) y est traitee au moyen d'equations representant les champs electromagnetiques. La nucleation et la croissance de poudres ultrafines sont incluses dans le modele via l'analyse des principaux moments de la distribution des tailles de particules. Enfin, tous les phenomenes physico-chimiques d'importance dans un milieu comme les plasmas thermiques, de meme que lem interactions, sont consideres. Le modele est applique ici a l'analyse de trois problematiques differentes et complementaires. La premiere concerne l'etude du melange gazeux d'un jet froid (He, N 2 ou O2), injecte au coeur d'une decharge d'argon/hydrogene ou d'argon/oxygene. La comparaison des predictions du modele avec des mesures experimentales obtenues par une sonde enthalpique permet une validation partielle de ce dernier. La deuxieme problematique a trait a l'etude numerique de la pyrolyse du methane en reacteur a plasma h.f. Elle met en evidence les difficultes de convergence de la methode numerique lorsque appliquee a la resolution d'ecoulements reactifs a haute temperature. Finalement, le dernier sujet aborde dans cette these, soit l'analyse systematique des principales conditions d'operation d'un reacteur h.f utilise pour la synthese reactive de poudres ultrafines de silicium, engage tous les elements theoriques du modele. Il implique en effet la decomposition thermique d'un precurseur gazeux, le tetrachlorure de silicium, la

  2. Adsorption de gaz sur les materiaux microporeux modelisation, thermodynamique et applications (United States)

    Richard, Marc-Andre


    Nos travaux sur l'adsorption de gaz dans les materiaux microporeux s'inscrivent dans le cadre des recherches visant a augmenter l'efficacite du stockage de l'hydrogene a bord des vehicules. Notre objectif etait d'etudier la possibilite d'utiliser l'adsorption afin d'ameliorer l'efficacite de la liquefaction de l'hydrogene des systemes a petite echelle. Nous avons egalement evalue les performances d'un systeme de stockage cryogenique de l'hydrogene base sur la physisorption. Comme nous avons affaire a des plages de temperatures particulierement etendues et a de hautes pressions dans la region supercritique du gaz, nous avons du commencer par travailler sur la modelisation et la thermodynamique de l'adsorption. La representation de la quantite de gaz adsorbee en fonction de la temperature et de la pression par un modele semi-empirique est un outil utile pour determiner la masse de gaz adsorbee dans un systeme mais egalement pour calculer les effets thermiques lies a l'adsorption. Nous avons adapte le modele Dubinin-Astakhov (D-A) pour modeliser des isothermes d'adsorption d'hydrogene, d'azote et de methane sur du charbon actif a haute pression et sur une grande plage de temperatures supercritiques en considerant un volume d'adsorption invariant. Avec cinq parametres de regression (incluant le volume d'adsorption Va), le modele que nous avons developpe permet de tres bien representer des isothermes experimentales d'adsorption d'hydrogene (de 30 a 293 K, jusqu'a 6 MPa), d'azote (de 93 a 298 K, jusqu'a 6 MPa) et de methane (de 243 a 333 K, jusqu'a 9 MPa) sur le charbon actif. Nous avons calcule l'energie interne de la phase adsorbee a partir du modele en nous servant de la thermodynamique des solutions sans negliger le volume d'adsorption. Par la suite, nous avons presente les equations de conservation de la niasse et de l'energie pour un systeme d'adsorption et valide notre demarche en comparant des simulations et des tests d'adsorption et de desorption. En plus de l

  3. Ericksonian Approach to Experiential Education, Part 1: Developing the Stance of the Practitioner; Part 2: Tailoring Interventions; Part 3: Applying Specific Ericksonian Techniques. (United States)

    Itin, Christian

    This three-part workshop presentation explores the ideas of Milton Erickson on the therapeutic relationship and the therapeutic use of metaphor, and applies these ideas to experiential education and adventure therapy. Part 1 introduces the practitioner to the core philosophy within an Ericksonian approach: "utilization" of a client's…

  4. Towards a Capability Approach to Careers: Applying Amartya Sen's Thinking to Career Guidance and Development (United States)

    Robertson, Peter J.


    Amartya Sen's capability approach characterizes an individual's well-being in terms of what they are able to be, and what they are able to do. This framework for thinking has many commonalities with the core ideas in career guidance. Sen's approach is abstract and not in itself a complete or explanatory theory, but a case can be…

  5. Mytho-poetical thought as described by Ernst Cassirer and Lucian Blaga: a comparative approach applied to works of poetry

    Directory of Open Access Journals (Sweden)

    Emilia Ivancu


    Full Text Available In the present paper we would like to investigate the concept of mythothought as defined by two philosophers, Ernst Cassirer and Lucian Blaga, and the way in which the term may be applied to a chosen corpus of poetry from Romania, Wales and Ireland.

  6. Service Quality Measurement Using SERVQUAL. An Applied Comparative Study on Customer Perceptions and Expectations under an International Approach

    Directory of Open Access Journals (Sweden)

    Jorge MONGAY


    Full Text Available This research uses the methodology Servqual in order to measure the quality of service given by a public university in Barcelona (Spain to its study abroad students. The analysis explores the results not only from traditional approach based in a expectations versus perceptions point of view but from a more specific approach offering profiles of study abroad students from 5 different nationalities. The research collects information from 622 questionnaires and it provides useful insights related to future strategies for improving satisfaction and service at the host institution.

  7. An Overview of Modeling Approaches Applied to Aggregation-Based Fleet Management and Integration of Plug-in Electric Vehicles †

    Directory of Open Access Journals (Sweden)

    Shi You


    Full Text Available The design and implementation of management policies for plug-in electric vehicles (PEVs need to be supported by a holistic understanding of the functional processes, their complex interactions, and their response to various changes. Models developed to represent different functional processes and systems are seen as useful tools to support the related studies for different stakeholders in a tangible way. This paper presents an overview of modeling approaches applied to support aggregation-based management and integration of PEVs from the perspective of fleet operators and grid operators, respectively. We start by explaining a structured modeling approach, i.e., a flexible combination of process models and system models, applied to different management and integration studies. A state-of-the-art overview of modeling approaches applied to represent several key processes, such as charging management, and key systems, such as the PEV fleet, is then presented, along with a detailed description of different approaches. Finally, we discuss several considerations that need to be well understood during the modeling process in order to assist modelers and model users in the appropriate decisions of using existing, or developing their own, solutions for further applications.

  8. Applying Rock Engineering Systems (RES approach to Evaluate and Classify the Coal Spontaneous Combustion Potential in Eastern Alborz Coal Mines

    Directory of Open Access Journals (Sweden)

    Amir Saffari


    Full Text Available Subject analysis of the potential of spontaneous combustion in coal layers with analytical and numerical methods has been always considered as a difficult task because of the complexity of the coal behavior and the number of factors influencing it. Empirical methods, due to accounting for certain and specific factors, have not accuracy and efficiency for all positions. The Rock Engineering Systems (RES approach as a systematic method for analyzing and classifying is proposed in engineering projects. The present study is concerned with employing the RES approach to categorize coal spontaneous combustion in coal regions. Using this approach, the interaction of parameters affecting each other in an equal scale on the coal spontaneous combustion was evaluated. The Intrinsic, geological and mining characteristics of coal seams were studied in order to identifying important parameters. Then, the main stages of implementation of the RES method i.e. interaction matrix formation, coding matrix and forming a list category were performed. Later, an index of Coal Spontaneous Combustion Potential (CSCPi was determined to format the mathematical equation. Then, the obtained data related to the intrinsic, geological and mining, and special index were calculated for each layer in the case study (Pashkalat coal region, Iran. So, the study offers a perfect and comprehensive classification of the layers. Finally, by using the event of spontaneous combustion occurred in Pashkalat coal region, an initial validation for this systematic approach in the study area was conducted, which suggested relatively good concordance in Pashkalat coal region.

  9. Experiences with IR Top N optimization in a main memory DBMS: applying `the database approach' in new domains

    NARCIS (Netherlands)

    Blok, H.E.; Vries, A.P. de; Blanken, H.M.; Apers, P.M.G.


    Data abstraction and query processing techniques are usually studied in the domain of administrative applications. We present a case-study in the non-standard domain of (multimedia) information retrieval, mainly intended as a feasibility study in favor of the `database approach' to data management.

  10. Group Oral Review in the Reading Lab: A Means of Synthesizing Individualized Approaches Applied to One Body of Written Material. (United States)

    Tomlinson, Louise M.

    Theorists and researchers have indicated that the Group Oral Review (GOR) provides valuable classroom interaction. Some objectives of the GOR approach to reading (for developmental studies reading students) are as follows: to reinforce the process used in a reading assignment, to aid development of metacognitive awareness, to emphasize the idea…

  11. Modelisation de la diffusion sur les surfaces metalliques: De l'adatome aux processus de croissance (United States)

    Boisvert, Ghyslain

    Cette these est consacree a l'etude des processus de diffusion en surface dans le but ultime de comprendre, et de modeliser, la croissance d'une couche mince. L'importance de bien mai triser la croissance est primordiale compte tenu de son role dans la miniaturisation des circuits electroniques. Nous etudions ici les surface des metaux nobles et de ceux de la fin de la serie de transition. Dans un premier temps, nous nous interessons a la diffusion d'un simple adatome sur une surface metallique. Nous avons, entre autres, mis en evidence l'apparition d'une correlation entre evenements successifs lorsque la temperature est comparable a la barriere de diffusion, i.e., la diffusion ne peut pas etre associee a une marche aleatoire. Nous proposons un modele phenomenologique simple qui reproduit bien les resultats des simulations. Ces calculs nous ont aussi permis de montrer que la diffusion obeit a la loi de Meyer-Neldel. Cette loi stipule que, pour un processus active, le prefacteur augmente exponentiellement avec la barriere. En plus, ce travail permet de clarifier l'origine physique de cette loi. En comparant les resultats dynamiques aux resultats statiques, on se rend compte que la barriere extraite des calculs dynamiques est essentiellement la meme que celle obtenue par une approche statique, beaucoup plus simple. On peut donc obtenir cette barriere a l'aide de methodes plus precises, i.e., ab initio, comme la theorie de la fonctionnelle de la densite, qui sont aussi malheureusement beaucoup plus lourdes. C'est ce que nous avons fait pour plusieurs systemes metalliques. Nos resultats avec cette derniere approche se comparent tres bien aux resultats experimentaux. Nous nous sommes attardes plus longuement a la surface (111) du platine. Cette surface regorge de particularites interessantes, comme la forme d'equilibre non-hexagonale des i lots et deux sites d'adsorption differents pour l'adatome. De plus, des calculs ab initio precedents n'ont pas reussi a confirmer la

  12. Modeling and numerical study of two phase flow; Modelisation et etude numerique d'ecoulements diphasiques: 1- Modelisation d'un ecoulement homogene equilibre 2- Modelisation des collisions entre gouttelettes a l'aide d'un modele simplifie de type BGK

    Energy Technology Data Exchange (ETDEWEB)

    Champmartin, A.


    This thesis describes the modelization and the simulation of two-phase systems composed of droplets moving in a gas. The two phases interact with each other and the type of model to consider directly depends on the type of simulations targeted. In the first part, the two phases are considered as fluid and are described using a mixture model with a drift relation (to be able to follow the relative velocity between the two phases and take into account two velocities), the two-phase flows are assumed at the equilibrium in temperature and pressure. This part of the manuscript consists of the derivation of the equations, writing a numerical scheme associated with this set of equations, a study of this scheme and simulations. A mathematical study of this model (hyperbolicity in a simplified framework, linear stability analysis of the system around a steady state) was conducted in a frame where the gas is assumed baro-tropic. The second part is devoted to the modelization of the effect of inelastic collisions on the particles when the time of the simulation is shorter and the droplets can no longer be seen as a fluid. We introduce a model of inelastic collisions for droplets in a spray, leading to a specific Boltzmann kernel. Then, we build caricatures of this kernel of BGK type, in which the behavior of the first moments of the solution of the Boltzmann equation (that is mass, momentum, directional temperatures, variance of the internal energy) are mimicked. The quality of these caricatures is tested numerically at the end. (author) [French] Cette these decrit la modelisation et la simulation de systemes a deux phases composees de particules evoluant dans un gaz. Les deux phases interagissent entre elles et le type de modele a considerer depend directement du type de simulations envisagees. Dans une premiere partie, les deux phases sont considerees comme des fluides, elles sont decrites a l'aide d'un modele de melange avec une relation de derive (permettant de

  13. The Best of All Possible Worlds: Applying the Model Driven Architecture Approach to a JC3IEDM OWL Ontology Modeled in UML (United States)


    1 19th ICCRTS  The Best of All Possible Worlds:  Applying the Model Driven Architecture  Approach to a JC3IEDM  OWL  Ontology  Modeled in UML  Topic...utilization of the Ontology Definition Metamodel (ODM), a UML profile for expressing OWL constructs in that language, one can combine the power of semantic...modeling done in OWL with the substantive advantages associated with the Model Driven Architecture (MDA) software design approach, namely, the

  14. An approach to computing discrete adjoints for MPI-parallelized models applied to Ice Sheet System Model 4.11 (United States)

    Larour, Eric; Utke, Jean; Bovin, Anton; Morlighem, Mathieu; Perez, Gilberto


    Within the framework of sea-level rise projections, there is a strong need for hindcast validation of the evolution of polar ice sheets in a way that tightly matches observational records (from radar, gravity, and altimetry observations mainly). However, the computational requirements for making hindcast reconstructions possible are severe and rely mainly on the evaluation of the adjoint state of transient ice-flow models. Here, we look at the computation of adjoints in the context of the NASA/JPL/UCI Ice Sheet System Model (ISSM), written in C++ and designed for parallel execution with MPI. We present the adaptations required in the way the software is designed and written, but also generic adaptations in the tools facilitating the adjoint computations. We concentrate on the use of operator overloading coupled with the AdjoinableMPI library to achieve the adjoint computation of the ISSM. We present a comprehensive approach to (1) carry out type changing through the ISSM, hence facilitating operator overloading, (2) bind to external solvers such as MUMPS and GSL-LU, and (3) handle MPI-based parallelism to scale the capability. We demonstrate the success of the approach by computing sensitivities of hindcast metrics such as the misfit to observed records of surface altimetry on the northeastern Greenland Ice Stream, or the misfit to observed records of surface velocities on Upernavik Glacier, central West Greenland. We also provide metrics for the scalability of the approach, and the expected performance. This approach has the potential to enable a new generation of hindcast-validated projections that make full use of the wealth of datasets currently being collected, or already collected, in Greenland and Antarctica.



    Gheorghe Săvoiu; Constantin Manea


    The main aim of this paper is to attempt a theoretical delineation of a new econoscience now known as financial econometrics, which is as a result of a dual approach, one originally from economics to econometrics, followed by another one, articulate, from financial economics to financial econometrics, both purely theoretical, simultaneously stressing the importance of economic and financial modelling, historically detailing the emergence and development of this new econoscience, outlining its...

  16. Principles for identification of High Potency Category Chemicals for which the Dermal Sensitisation Threshold (DST) approach should not be applied. (United States)

    Roberts, David W; Api, Anne Marie; Safford, Robert J; Lalko, Jon F


    An essential step in ensuring the toxicological safety of chemicals used in consumer products is the evaluation of their skin sensitising potential. The sensitising potency, coupled with information on exposure levels, can be used in a Quantitative Risk Assessment (QRA) to determine an acceptable level of a given chemical in a given product. Where consumer skin exposure is low, a risk assessment can be conducted using the Dermal Sensitisation Threshold (DST) approach, avoiding the need to determine potency experimentally. Since skin sensitisation involves chemical reaction with skin proteins, the first step in the DST approach is to assess, on the basis of the chemical structure, whether the chemical is expected to be reactive or not. Our accompanying publication describes the probabilistic derivation of a DST of 64 μg/cm(2) for chemicals assessed as reactive. This would protect against 95% of chemicals assessed as reactive, but the remaining 5% would include chemicals with very high potency. Here we discuss the chemical properties and structural features of high potency sensitisers, and derive an approach whereby they can be identified and consequently excluded from application of the DST.

  17. Topology, divergence dates, and macroevolutionary inferences vary between different tip-dating approaches applied to fossil theropods (Dinosauria). (United States)

    Bapst, D W; Wright, A M; Matzke, N J; Lloyd, G T


    Dated phylogenies of fossil taxa allow palaeobiologists to estimate the timing of major divergences and placement of extinct lineages, and to test macroevolutionary hypotheses. Recently developed Bayesian 'tip-dating' methods simultaneously infer and date the branching relationships among fossil taxa, and infer putative ancestral relationships. Using a previously published dataset for extinct theropod dinosaurs, we contrast the dated relationships inferred by several tip-dating approaches and evaluate potential downstream effects on phylogenetic comparative methods. We also compare tip-dating analyses to maximum-parsimony trees time-scaled via alternative a posteriori approaches including via the probabilistic cal3 method. Among tip-dating analyses, we find opposing but strongly supported relationships, despite similarity in inferred ancestors. Overall, tip-dating methods infer divergence dates often millions (or tens of millions) of years older than the earliest stratigraphic appearance of that clade. Model-comparison analyses of the pattern of body-size evolution found that the support for evolutionary mode can vary across and between tree samples from cal3 and tip-dating approaches. These differences suggest that model and software choice in dating analyses can have a substantial impact on the dated phylogenies obtained and broader evolutionary inferences.

  18. Applying the Lessons of SARS to Pandemic Influenza: An Evidence-based Approach to Mitigating the Stress Experienced by Healthcare Workers


    Maunder, Robert G.; Peladeau, Nathalie; Leszcz, Molyn; Romano, Donna; Savage, Diane; Rose, Marci; Adam, Mary Anne; Schulman, Rabbi Bernard


    We describe an evidence-based approach to enhancing the resilience of healthcare workers in preparation for an influenza pandemic, based on evidence about the stress associated with working in healthcare during the SARS outbreak. SARS was associated with significant long-term stress in healthcare workers, but not with increased mental illness. Reducing pandemic-related stress may best be accomplished through interventions designed to enhance resilience in psychologically healthy people. Appli...

  19. Putting Business Students in the Shoes of an Executive: An Applied Learning Approach to Developing Decision Making Skills

    Directory of Open Access Journals (Sweden)

    Jeanny Liu, PhD


    Full Text Available Students often struggle with how to translate textbook concepts into real-world applications that allow them to personally experience the importance of these concepts. This is an ongoing challenge within all disciplines in higher education. To address this, faculty design their courses using methods beyond traditional classroom lectures to facilitate and reinforce student learning. The authors believe that students who are given hands-on problem-solving opportunities are more likely to retain such knowledge and apply it outside the classroom, in the workplace, volunteer activities, and other personal pursuits. In an attempt to engage students and provide them with meaningful opportunities to apply course concepts, the authors have initiated a number of experiential learning methods in the classroom. Since fall of 2008, elements of problem-based learning were integrated in the authors’ business courses. Specifically, real-world consulting projects were introduced into their classrooms. This paper focuses on the authors’ experiences implementing problem-based learning processes and practical project assignments that actively engage students in the learning process. The experiences and the feedback gathered from students and executives who participated in the “realworld” project are reported in this paper.

  20. A Novel Approach Utilizing pnetCDF applying to the WRF-CMAQ two-way coupled model (United States)

    Wong, David; Yang, Cheng-en; Mathur, Rohit; Pleim, Jonathan; Fu, Joshua; Wong, Kwai; Gao, Yang


    I/O is part of a scientific model and it takes up a significant portion of the simulation. There is no exception for the newly developed WRF-CMAQ two-way coupled model at US EPA. This two-way coupled meteorology and air quality model is composed of the Weather Research and Forecasting (WRF) model and the Community Multiscale Air Quality (CMAQ) model. We are using this two-way model to evaluate how accurate it simulates the effects of aerosol loading on radiative forcing between 1990 and 2010 when there were substantial aerosol emissions such as SO2 and NOx, reduction in North America and Europe. The I/O scheme in the current model does not make use of any parallel file system or parallel I/O approach. In addition the I/O takes about 15% - 28% of the entire simulation. Our novel approach not only utilizes pnetCDF parallel I/O technique but goes one step further to aggregate the data locally, i.e. along column dimension or row dimension in the spatial domain. This approach not only reduces the I/O traffic contention but also aggregated data enhances the I/O efficiency. In terms of I/O time, we have shown this method is about 6 to 10 times faster than the current existing I/O scheme in the model and about 20% - 3 times faster than strict application of pnetCDF. We are currently running the model on a Cray XE6 machine and finding ways to reduce the overall simulation time is crucial to the success to achieve our objective.

  1. Microbial communities analysis assessed by pyrosequencing--a new approach applied to conservation state studies of mural paintings. (United States)

    Rosado, T; Mirão, J; Candeias, A; Caldeira, A T


    The knowledge about the microbial communities present in mural paintings is of utmost importance to develop effective conservation and mitigation strategies. The present paper describes a methodological approach for the detailed characterisation of microorganisms thriving in mural paintings by combining culture-dependent methods that allow the identification of microorganisms capable of growing in the laboratory conditions and to obtain high cell densities for further studies, and culture independent methods, such as denaturing gradient gel electrophoresis (DGGE) and pyrosequencing. The coupled use of culture-dependent methods and DGGE does not give enough information to investigate the diversity and abundance of microorganisms present in wall paintings. Pyrosequencing, a novel molecular technique, used here for the first time in this area of research, allowed the identification of a large number of microorganisms, confirming some already identified by the cultivation-dependent methods such as fungi of the genera Penicillium and Cladosporium, but also providing a great contribution in the identification of several genera and species, not previously identified in these artworks, giving also a detailed overview of contaminants which was not possible with the other approaches. The results obtained on several mural painting samples show a strong relationship between the most deteriorated areas of the paintings and higher microbial contamination.

  2. Applying machine learning approaches to improving the accuracy of breast-tumour diagnosis via fine needle aspiration

    Institute of Scientific and Technical Information of China (English)

    YUAN Qian-fei; CAI Cong-zhong; XIAO Han-guang; LIU Xing-hua


    Diagnosis and treatment of breast cancer have been improved during the last decade; however, breast cancer is still a leading cause of death among women in the whole world. Early detection and accurate diagnosis of this disease has been demonstrated an approach to long survival of the patients. As an attempt to develop a reliable diagnosing method for breast cancer, we integrated support vector machine (SVM), k-nearest neighbor and probabilistic neural network into a complex machine learning approach to detect malignant breast tumour through a set of indicators consisting of age and ten cellular features of fine-needle aspiration of breast which were ranked according to signal-to-noise ratio to identify determinants distinguishing benign breast tumours from malignant ones. The method turned out to significantly improve the diagnosis, with a sensitivity of 94.04%, a specificity of 97.37%, and an overall accuracy up to 96.24% when SVM was adopted with the sigmoid kernel function under 5-fold cross validation. The results suggest that SVM is a promising methodology to be further developed into a practical adjunct implement to help discerning benign and malignant breast tumours and thus reduce the incidence of misdiagnosis.

  3. Optimal control of open quantum systems: a combined surrogate hamiltonian optimal control theory approach applied to photochemistry on surfaces. (United States)

    Asplund, Erik; Klüner, Thorsten


    In this paper, control of open quantum systems with emphasis on the control of surface photochemical reactions is presented. A quantum system in a condensed phase undergoes strong dissipative processes. From a theoretical viewpoint, it is important to model such processes in a rigorous way. In this work, the description of open quantum systems is realized within the surrogate hamiltonian approach [R. Baer and R. Kosloff, J. Chem. Phys. 106, 8862 (1997)]. An efficient and accurate method to find control fields is optimal control theory (OCT) [W. Zhu, J. Botina, and H. Rabitz, J. Chem. Phys. 108, 1953 (1998); Y. Ohtsuki, G. Turinici, and H. Rabitz, J. Chem. Phys. 120, 5509 (2004)]. To gain control of open quantum systems, the surrogate hamiltonian approach and OCT, with time-dependent targets, are combined. Three open quantum systems are investigated by the combined method, a harmonic oscillator immersed in an ohmic bath, CO adsorbed on a platinum surface, and NO adsorbed on a nickel oxide surface. Throughout this paper, atomic units, i.e., ℏ = m(e) = e = a(0) = 1, have been used unless otherwise stated.

  4. Utility of the pooling approach as applied to whole genome association scans with high-density Affymetrix microarrays

    Directory of Open Access Journals (Sweden)

    Gray Joanna


    Full Text Available Abstract Background We report an attempt to extend the previously successful approach of combining SNP (single nucleotide polymorphism microarrays and DNA pooling (SNP-MaP employing high-density microarrays. Whereas earlier studies employed a range of Affymetrix SNP microarrays comprising from 10 K to 500 K SNPs, this most recent investigation used the 6.0 chip which displays 906,600 SNP probes and 946,000 probes for the interrogation of CNVs (copy number variations. The genotyping assay using the Affymetrix SNP 6.0 array is highly demanding on sample quality due to the small feature size, low redundancy, and lack of mismatch probes. Findings In the first study published so far using this microarray on pooled DNA, we found that pooled cheek swab DNA could not accurately predict real allele frequencies of the samples that comprised the pools. In contrast, the allele frequency estimates using blood DNA pools were reasonable, although inferior compared to those obtained with previously employed Affymetrix microarrays. However, it might be possible to improve performance by developing improved analysis methods. Conclusions Despite the decreasing costs of genome-wide individual genotyping, the pooling approach may have applications in very large-scale case-control association studies. In such cases, our study suggests that high-quality DNA preparations and lower density platforms should be preferred.

  5. First and second law analysis applied to building envelope: A theoretical approach on the potentiality of Bejan’s theory

    Directory of Open Access Journals (Sweden)

    Cesare Biserni


    Full Text Available Especially in the last decade, efforts have been made in developing the sustainable building assessment tools, which are usually performed based on fundamentals of the First Law of Thermodynamics. However, this approach does not provide a faithful thermodynamic evaluation of the overall energy conversion processes that occur in buildings, and a more robust approach should be followed. The relevance of Second Law analysis has been here highlighted: in addition to the calculation of energy balances, the concept of exergy is used to evaluate the quality of energy sources, resulting in a higher flexibility of strategies to optimize a building design. Reviews of the progress being made with the constructal law show that diverse phenomena can be considered manifestations of the tendency towards optimization captured by the constructal law. The studies based on First and Second Principle of Thermodynamics results to be affected by the extreme generality of the two laws, which is consequent of the fact that in thermodynamics the “any system” is a black box with no information about design, organization and evolution. In this context, an exploratory analysis on the potentiality of constructal theory, that can be considered a law of thermodynamics, has been finally outlined in order to assess the energy performance in building design.

  6. Properties of an almost localized Fermi liquid in an applied magnetic field revisited: a statistically consistent Gutzwiller approach. (United States)

    Wysokiński, Marcin M; Spałek, Jozef


    We discuss the Hubbard model in an applied magnetic field and analyze the properties of neutral spin-[Formula: see text] fermions within the so-called statistically consistent Gutzwiller approximation. The magnetization curve reproduces in a semiquantitative manner the experimental data for liquid (3)He in the regime of moderate correlations and in the presence of a small number of vacant cells, modeled by a non-half-filled band situation, when a small number of vacancies (∼5%) is introduced in the virtual fcc lattice. We also present the results for the magnetic susceptibility and the specific heat, in which a metamagnetic-like behavior is also singled out in a non-half-filled band case.

  7. Modelisation and Simulation of Heat and Mass Transfers during Solar Drying of Sewage Sludge with Introduction of Real Climatic Conditions

    Directory of Open Access Journals (Sweden)

    N. Ben Hassine


    Full Text Available Sewage sludge presents a real problem with the urban and industrial expanding. So, the drying technique is indispensable in the sludge treatment process to minimize its volume and its revalorization. For cost and environmental reasons, the solar drying is becoming increasingly attractive for small and medium wastewater treatment plants. Therefore, the aim of this work is the modelisation of solar dryer of residual sludge. The model studied is a rectangular agricultural greenhouse. In the lower part, the sludge (assimilated to a porous medium, acts as an absorber. It is subjected to a forced laminar flow. The transfers in the greenhouse and the porous medium are described respectively by the classical equations of forced convection and the Darcy-Brinkman-Forchheimer model. The implicit finite difference method is used to discretize the governing differential equation. The algebraic systems obtained are solved using the Gauss, Thomas and Gauss-Seidel algorithms. In order to complete the model and to determine the drying rate we associate a model of the sewage sludge drying kinetics. This work is realized with the meteorological data of the Tataouine region in the south of Tunisia. This data have undergone statistical treatment using the Liu and Jordan method. In order to show the advantages of solar drying, we especially studied the various transfer modes, the drying kinetics and the dryer performance.

  8. A simplified approach to estimating the distribution of occasionally-consumed dietary components, applied to alcohol intake

    Directory of Open Access Journals (Sweden)

    Julia Chernova


    Full Text Available Abstract Background Within-person variation in dietary records can lead to biased estimates of the distribution of food intake. Quantile estimation is especially relevant in the case of skewed distributions and in the estimation of under- or over-consumption. The analysis of the intake distributions of occasionally-consumed foods presents further challenges due to the high frequency of zero records. Two-part mixed-effects models account for excess-zeros, daily variation and correlation arising from repeated individual dietary records. In practice, the application of the two-part model with random effects involves Monte Carlo (MC simulations. However, these can be time-consuming and the precision of MC estimates depends on the size of the simulated data which can hinder reproducibility of results. Methods We propose a new approach based on numerical integration as an alternative to MC simulations to estimate the distribution of occasionally-consumed foods in sub-populations. The proposed approach and MC methods are compared by analysing the alcohol intake distribution in a sub-population of individuals at risk of developing metabolic syndrome. Results The rate of convergence of the results of MC simulations to the results of our proposed method is model-specific, depends on the number of draws from the target distribution, and is relatively slower at the tails of the distribution. Our data analyses also show that model misspecification can lead to incorrect model parameter estimates. For example, under the wrong model assumption of zero correlation between the components, one of the predictors turned out as non-significant at 5 % significance level (p-value 0.062 but it was estimated as significant in the correctly specified model (p-value 0.016. Conclusions The proposed approach for the analysis of the intake distributions of occasionally-consumed foods provides a quicker and more precise alternative to MC simulation methods, particularly in the

  9. A non-statistical regularization approach and a tensor product decomposition method applied to complex flow data (United States)

    von Larcher, Thomas; Blome, Therese; Klein, Rupert; Schneider, Reinhold; Wolf, Sebastian; Huber, Benjamin


    Handling high-dimensional data sets like they occur e.g. in turbulent flows or in multiscale behaviour of certain types in Geosciences are one of the big challenges in numerical analysis and scientific computing. A suitable solution is to represent those large data sets in an appropriate compact form. In this context, tensor product decomposition methods currently emerge as an important tool. One reason is that these methods often enable one to attack high-dimensional problems successfully, another that they allow for very compact representations of large data sets. We follow the novel Tensor-Train (TT) decomposition method to support the development of improved understanding of the multiscale behavior and the development of compact storage schemes for solutions of such problems. One long-term goal of the project is the construction of a self-consistent closure for Large Eddy Simulations (LES) of turbulent flows that explicitly exploits the tensor product approach's capability of capturing self-similar structures. Secondly, we focus on a mixed deterministic-stochastic subgrid scale modelling strategy currently under development for application in Finite Volume Large Eddy Simulation (LES) codes. Advanced methods of time series analysis for the databased construction of stochastic models with inherently non-stationary statistical properties and concepts of information theory based on a modified Akaike information criterion and on the Bayesian information criterion for the model discrimination are used to construct surrogate models for the non-resolved flux fluctuations. Vector-valued auto-regressive models with external influences form the basis for the modelling approach [1], [2], [4]. Here, we present the reconstruction capabilities of the two modeling approaches tested against 3D turbulent channel flow data computed by direct numerical simulation (DNS) for an incompressible, isothermal fluid at Reynolds number Reτ = 590 (computed by [3]). References [1] I

  10. Gradient-Driven Molecule Construction: An Inverse Approach Applied to the Design of Small-Molecule Fixating Catalysts

    CERN Document Server

    Weymuth, Thomas


    Rational design of molecules and materials usually requires extensive screening of molecular structures for the desired property. The inverse approach to deduce a structure for a predefined property would be highly desirable, but is, unfortunately, not well-defined. However, feasible strategies for such an inverse design process may be successfully developed for specific purposes. We discuss options for calculating 'jacket' potentials that fulfill a predefined target requirement - a concept that we recently introduced [T. Weymuth, M. Reiher, MRS Proceediungs, 2013, 1524, DOI:10.1557/opl.2012.1764]. We consider the case of small-molecule activating transition metal catalysts. As a target requirement we choose the vanishing geometry gradients on all atoms of a subsystem consisting of a metal center binding the small molecule to be activated. The jacket potential can be represented within a full quantum model or by a sequence of approximations of which a field of electrostatic point charges is the simplest. In a...

  11. Ethics of clear health communication: applying the CLEAN Look approach to communicate biobanking information for cancer research. (United States)

    Koskan, Alexis; Arevalo, Mariana; Gwede, Clement K; Quinn, Gwendolyn P; Noel-Thomas, Shalewa A; Luque, John S; Wells, Kristen J; Meade, Cathy D


    Cancer innovations, such as biobanking technologies, are continuously evolving to improve our understanding and knowledge about cancer prevention and treatment modalities. However, the public receives little communication about biobanking and is often unaware about this innovation until asked to donate biospecimens. It is the researchers' ethical duty to provide clear communications about biobanking and biospecimen research. Such information allows the public to understand biobanking processes and facilitates informed decision making about biospecimen donation. The aims of this paper are 1) to examine the importance of clear communication as an ethical imperative when conveying information about cancer innovations and 2) to illustrate the use of an organizing framework, the CLEAN ( C ulture, L iteracy, E ducation, A ssessment, and N etworking) Look approach for creating educational priming materials about the topic of biobanking.

  12. Applied Laplace transforms and z-transforms for scientists and engineers a computational approach using a Mathematica package

    CERN Document Server

    Graf, Urs


    The theory of Laplace transformation is an important part of the mathematical background required for engineers, physicists and mathematicians. Laplace transformation methods provide easy and effective techniques for solving many problems arising in various fields of science and engineering, especially for solving differential equations. What the Laplace transformation does in the field of differential equations, the z-transformation achieves for difference equations. The two theories are parallel and have many analogies. Laplace and z­ transformations are also referred to as operational calculus, but this notion is also used in a more restricted sense to denote the operational calculus of Mikusinski. This book does not use the operational calculus of Mikusinski, whose approach is based on abstract algebra and is not readily accessible to engineers and scientists. The symbolic computation capability of Mathematica can now be used in favor of the Laplace and z-transformations. The first version of the Mathema...

  13. A Continuing Approach, from Financial Economics to Financial Econometrics or the Econometric Thinking Applied to Financial Economics

    Directory of Open Access Journals (Sweden)

    Gheorghe Săvoiu


    Full Text Available The main aim of this paper is to attempt a theoretical delineation of a new econoscience now known as financial econometrics, which is as a result of a dual approach, one originally from economics to econometrics, followed by another one, articulate, from financial economics to financial econometrics, both purely theoretical, simultaneously stressing the importance of economic and financial modelling, historically detailing the emergence and development of this new econoscience, outlining its subject and objectives, and describing some of the most commonly used methods and models, while noting the presence of increasingly sharp competition of econophysics, sociophysics and economy quantum, in the universe of modelling the processes and phenomena in classical economics and financial economics.

  14. Applying participatory approaches in the evaluation of surveillance systems: A pilot study on African swine fever surveillance in Corsica. (United States)

    Calba, Clémentine; Antoine-Moussiaux, Nicolas; Charrier, François; Hendrikx, Pascal; Saegerman, Claude; Peyre, Marisa; Goutard, Flavie L


    The implementation of regular and relevant evaluations of surveillance systems is critical in improving their effectiveness and their relevance whilst limiting their cost. The complex nature of these systems and the variable contexts in which they are implemented call for the development of flexible evaluation tools. Within this scope, participatory tools have been developed and implemented for the African swine fever (ASF) surveillance system in Corsica (France). The objectives of this pilot study were, firstly, to assess the applicability of participatory approaches within a developed environment involving various stakeholders and, secondly, to define and test methods developed to assess evaluation attributes. Two evaluation attributes were targeted: the acceptability of the surveillance system and its the non-monetary benefits. Individual semi-structured interviews and focus groups were implemented with representatives from every level of the system. Diagramming and scoring tools were used to assess the different elements that compose the definition of acceptability. A contingent valuation method, associated with proportional piling, was used to assess the non-monetary benefits, i.e., the value of sanitary information. Sixteen stakeholders were involved in the process, through 3 focus groups and 8 individual semi-structured interviews. Stakeholders were selected according to their role in the system and to their availability. Results highlighted a moderate acceptability of the system for farmers and hunters and a high acceptability for other representatives (e.g., private veterinarians, local laboratories). Out of the 5 farmers involved in assessing the non-monetary benefits, 3 were interested in sanitary information on ASF. The data collected via participatory approaches enable relevant recommendations to be made, based on the Corsican context, to improve the current surveillance system.

  15. Introduction of culturally sensitive HIV prevention in the context of female initiation rites: an applied anthropological approach in Mozambique. (United States)

    Kotanyi, Sophie; Krings-Ney, Brigitte


    In Mozambique, initiation rites represent the most appropriate socio-cultural context for dealing with sexuality for a large part of the population. As the group most vulnerable to HIV exposure, HIV-prevention counselling could be ideally introduced to young women during initiation rites. This article demonstrates how interventions can take advantage of the positive aspects of this tradition. We discuss local notions of social 'contamination' versus biological 'contamination,' and we present a culturally sensitive communication strategy to bridge the divergent paradigms around AIDS-similar symptoms. Because of the emotional importance of the initiation rites, the suggested approach goes far beyond cognitive knowledge. After training, the godmothers in initiation rites became highly motivated to teach novice girls about HIV prevention and they trained other elderly women as well. Thus, the initiation rites turned into a process of empowerment for women in their own communities. A central agenda of the female initiation rites in Mozambique is to inculcate respect towards ancestors, elders, authorities and others; however, this respectful attitude between genders and between generations is disappearing due to factors like warfare and the cash economy. HIV-prevention counselling may be successfully introduced into initiation rites because of the unconscious, emotional impact of the process on the initiates' behaviour. Other studies have shown that cognitive knowledge is not enough to lead to behavioural changes. Without changing the traditional initiation rites for females, which in Mozambique includes no genital cutting, a complementary approach introduces HIV-prevention counselling during ritual counselling moments, thereby motivating godmothers and novice girls and young women to be more aware and take precautions to prevent HIV infection.

  16. Pitfalls of the Geographic Population Structure (GPS) Approach Applied to Human Genetic History: A Case Study of Ashkenazi Jews. (United States)

    Flegontov, Pavel; Kassian, Alexei; Thomas, Mark G; Fedchenko, Valentina; Changmai, Piya; Starostin, George


    In a recent interdisciplinary study, Das et al. have attempted to trace the homeland of Ashkenazi Jews and of their historical language, Yiddish (Das et al. 2016 Localizing Ashkenazic Jews to Primeval Villages in the Ancient Iranian Lands of Ashkenaz. Genome Biol Evol. 8:1132-1149). Das et al. applied the geographic population structure (GPS) method to autosomal genotyping data and inferred geographic coordinates of populations supposedly ancestral to Ashkenazi Jews, placing them in Eastern Turkey. They argued that this unexpected genetic result goes against the widely accepted notion of Ashkenazi origin in the Levant, and speculated that Yiddish was originally a Slavic language strongly influenced by Iranian and Turkic languages, and later remodeled completely under Germanic influence. In our view, there are major conceptual problems with both the genetic and linguistic parts of the work. We argue that GPS is a provenancing tool suited to inferring the geographic region where a modern and recently unadmixed genome is most likely to arise, but is hardly suitable for admixed populations and for tracing ancestry up to 1,000 years before present, as its authors have previously claimed. Moreover, all methods of historical linguistics concur that Yiddish is a Germanic language, with no reliable evidence for Slavic, Iranian, or Turkic substrata.

  17. Applying System Dynamics Approach to the Fast Fashion Supply Chain: Case Study of an SME in Indonesia

    Directory of Open Access Journals (Sweden)

    Mariany W Lidia


    Full Text Available The fashion industry is the biggest contributor among the 14 creative industries in Indonesia. Nowadays many apparel companies are shifting toward the vertical integration. Since speed is everything to be successful in the apparel industry, fast fashion retailers must quickly respond to the market demand. This papers aims to develop a model of the supply chain of a small and medium scale enterprise (SME of an apparel company in Indonesia and to propose a decision support system using System Dynamics (SD and helps the management to identify the best business strategy. Simulated scenarios can help the management to identify the most appropriate policy to be applied in the future. Case study method was used in this research where data were collected from a typical fast fashion firm in Indonesia that produces its own wares ranging from raw materials to be ready-to-wear clothes, has three stores, a warehouse and is running online sales system. We analyses the result of many simulations in a fashion company from an operational point of view and from them we derive suggestions about the future business strategy in a small and medium fashion company in Indonesia. Keywords: system dynamics, fast fashion, supply chain management, SME, Indonesia

  18. Extraction of human gait signatures: an inverse kinematic approach using Groebner basis theory applied to gait cycle analysis (United States)

    Barki, Anum; Kendricks, Kimberly; Tuttle, Ronald F.; Bunker, David J.; Borel, Christoph C.


    This research highlights the results obtained from applying the method of inverse kinematics, using Groebner basis theory, to the human gait cycle to extract and identify lower extremity gait signatures. The increased threat from suicide bombers and the force protection issues of today have motivated a team at Air Force Institute of Technology (AFIT) to research pattern recognition in the human gait cycle. The purpose of this research is to identify gait signatures of human subjects and distinguish between subjects carrying a load to those subjects without a load. These signatures were investigated via a model of the lower extremities based on motion capture observations, in particular, foot placement and the joint angles for subjects affected by carrying extra load on the body. The human gait cycle was captured and analyzed using a developed toolkit consisting of an inverse kinematic motion model of the lower extremity and a graphical user interface. Hip, knee, and ankle angles were analyzed to identify gait angle variance and range of motion. Female subjects exhibited the most knee angle variance and produced a proportional correlation between knee flexion and load carriage.

  19. Applying a System Dynamics Approach for Modeling Groundwater Dynamics to Depletion under Different Economical and Climate Change Scenarios

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    Hamid Balali


    Full Text Available In the recent decades, due to many different factors, including climate change effects towards be warming and lower precipitation, as well as some structural policies such as more intensive harvesting of groundwater and low price of irrigation water, the level of groundwater has decreased in most plains of Iran. The objective of this study is to model groundwater dynamics to depletion under different economic policies and climate change by using a system dynamics approach. For this purpose a dynamic hydro-economic model which simultaneously simulates the farmer’s economic behavior, groundwater aquifer dynamics, studied area climatology factors and government economical policies related to groundwater, is developed using STELLA 10.0.6. The vulnerability of groundwater balance is forecasted under three scenarios of climate including the Dry, Nor and Wet and also, different scenarios of irrigation water and energy pricing policies. Results show that implementation of some economic policies on irrigation water and energy pricing can significantly affect on groundwater exploitation and its volume balance. By increasing of irrigation water price along with energy price, exploitation of groundwater will improve, in so far as in scenarios S15 and S16, studied area’s aquifer groundwater balance is positive at the end of planning horizon, even in Dry condition of precipitation. Also, results indicate that climate change can affect groundwater recharge. It can generally be expected that increases in precipitation would produce greater aquifer recharge rates.

  20. A generic sample preparation approach for LC–MS/MS bioanalysis of therapeutic monoclonal antibodies in serum applied to Infliximab

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    Anne J. Kleinnijenhuis


    Full Text Available In this study, we developed a generic bioanalytical workflow providing sensitive, specific, and accurate absolute quantification of therapeutic monoclonal antibodies in serum. The workflow involves magnetic beads coated with protein A to pull-down therapeutic monoclonal antibodies with affinity for protein A from the biological matrix, followed by tryptic digestion and LC-MS/MS quantification of a unique signature peptide, considering of course the matrix of interest and other present mAbs, if applicable. The feasibility of this approach was demonstrated for Infliximab (trade name Remicade in rat serum. The assigned signature peptide was monitored in the selected reaction monitoring (SRM mode. Assay variability was determined to be below 20%, except at the QC low level, which was provided through optimization of the sample preparation and monitoring of the LC-MS/MS using a stable isotope labeled signature peptide as internal standard. The 100 ng/ml lower limit of quantification using only 25 μl sample volume, is generally considered as sufficient for pharmaceutical development purposes for monoclonal antibodies.

  1. Space base laser torque applied on LEO satellites of various geometries at satellite’s closest approach

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    N.S. Khalifa


    Full Text Available In light of using laser power in space applications, the motivation of this paper is to use a space based solar pumped laser to produce a torque on LEO satellites of various shapes. It is assumed that there is a space station that fires laser beam toward the satellite so the beam spreading due to diffraction is considered to be the dominant effect on the laser beam propagation. The laser torque is calculated at the point of closest approach between the space station and some sun synchronous low Earth orbit cubesats. The numerical application shows that space based laser torque has a significant contribution on the LEO cubesats. It has a maximum value in the order of 10−8 Nm which is comparable with the residual magnetic moment. However, it has a minimum value in the order 10−11 Nm which is comparable with the aerodynamic and gravity gradient torque. Consequently, space based laser torque can be used as an active attitude control system.

  2. Environmental and traffic-related parameters affecting road dust composition: A multi-technique approach applied to Venice area (Italy) (United States)

    Valotto, Gabrio; Rampazzo, Giancarlo; Visin, Flavia; Gonella, Francesco; Cattaruzza, Elti; Glisenti, Antonella; Formenton, Gianni; Tieppo, Paulo


    Road dust is a non-exhaust source of atmospheric particulate by re-suspension. It is composed of particles originating from natural sources as well as other non-exhaust source such as tire, brake and asphalt wear. The discrimination between atmospheric particles directly emitted from abrasion process and those related to re-suspension is therefore an open issue, as far as the percentage contribution of non-exhaust emissions is becoming more considerable due also to the recent policy actions and the technological upgrades in the automotive field, focused on the reduction of exhaust emissions. In this paper, road dust collected along the bridge that connects Venice (Italy) to the mainland is characterized with a multi-technique approach in order to determine its composition depending on environmental as well as traffic-related conditions. Six pollutant sources of road dust particles were identified by cluster analysis: brake, railway, tire, asphalt, soil + marine, and mixed combustions. Considering the lack of information on this matrix in this area, this study is intended to provide useful information for future identification of road dust re-suspension source in atmospheric particulate.

  3. Applying the collective impact approach to address non-native species: A case study of the Great Lakes Phragmites Collaborative (United States)

    Braun, H. B.; Kowalski, Kurt P.; Hollins, K.


    To address the invasion of non-native Phragmites in the Great Lakes, researchers at the U.S. Geological Survey—Great Lakes Science Center partnered with the Great Lakes Commission in 2012 to establish the Great Lakes Phragmites Collaborative (GLPC). The GLPC is a regional-scale partnership established to improve collaboration among stakeholders and increase the effectiveness of non-native Phragmites management and research. Rather than forming a traditional partnership with a narrowly defined goal, the GLPC follows the principles of collective impact to engage stakeholders, guide progress, and align resources to address this complex, regional challenge. In this paper, the concept and tenets of collective impact are described, the GLPC is offered as a model for other natural resource-focused collective impact efforts, and steps for establishing collaboratives are presented. Capitalizing on the interactive collective impact approach, the GLPC is moving toward a broadly accepted common agenda around which agencies and individuals will be able to better align their actions and generate measureable progress in the regional campaign to protect healthy, diverse ecosystems from damage caused by non-native Phragmites.

  4. A multibody approach applied to the study of driver injuries due to a narrow-track wheeled tractor rollover

    Directory of Open Access Journals (Sweden)

    Simone Pascuzzi


    Full Text Available This paper proposes the use of the multibody approach to evaluate the severity of the injuries to the driver associated with rollover of an agricultural tractor. A simple rollover accident of a narrow-track wheeled tractor was simulated in the multibody-FEM Madymo environment and the biomechanical damage to the operator with and without 2-point pelvic restraint was analysed. The structure of the tractor was considered to be unbendable, whereas i infinitely rigid, ii clay-based and iii sand-based soils have been studied. The obtained results highlight the important role played by the seat belt in confining the farm operator within the safety volume maintained by the rollover protective structure (ROPS of the tractor so that the injuries are reduced. The deformation of the soil produces lower acceleration and velocity values than those obtained with a rigid soil. On the other hand, as soil plastic deformations increase, the penetration of ROPS into the soil also increases, thus reducing the safety volume of the tractor and increasing the probability of interactions between the operator and the soil.

  5. The novel approach to enhance seed security: dual anti-counterfeiting methods applied on tobacco pelleted seeds.

    Directory of Open Access Journals (Sweden)

    Yajing Guan

    Full Text Available Seed security is of prime importance for agriculture. To protect true seeds from being faked, more secure dual anti-counterfeiting technologies for tobacco (Nicotiana tabacum L. pelleted seed were developed in this paper. Fluorescein (FR, rhodamine B (RB, and magnetic powder (MP were used as anti-counterfeiting labels. According to their different properties and the special seed pelleting process, four dual-labeling treatments were conducted for two tobacco varieties, MS Yunyan85 (MSYY85 and Honghua Dajinyuan (HHDJY. Then the seed germination and seedling growth status were investigated, and the fluorescence in cracked pellets and developing seedlings was observed under different excitation lights. The results showed that FR, RB, and MP had no negative effects on the germination, seedling growth, and MDA content of the pelleted seeds, and even some treatments significantly enhanced seedling dry weight, vigor index, and shoot height in MS YY85, and increased SOD activity and chlorophyll content in HHDJY as compared to the control. In addition, the cotyledon tip of seedlings treated with FR and MP together represented bright green fluorescence under illumination of blue light (478 nm. And the seedling cotyledon vein treated with RB and MP together showed red fluorescence under green light (546 nm. All seeds pelleted with magnetic powder of proper concentration could be attracted by a magnet. Thus, it indicated that those new dual-labeling methods that fluorescent compound and magnetic powder simultaneously applied in the same seed pellets definitely improved anti-counterfeiting technology and enhanced the seed security. This technology will ensure that high quality seed will be used in the crop production.

  6. The novel approach to enhance seed security: dual anti-counterfeiting methods applied on tobacco pelleted seeds. (United States)

    Guan, Yajing; Wang, Jianchen; Tian, Yixin; Hu, Weimin; Zhu, Liwei; Zhu, Shuijin; Hu, Jin


    Seed security is of prime importance for agriculture. To protect true seeds from being faked, more secure dual anti-counterfeiting technologies for tobacco (Nicotiana tabacum L.) pelleted seed were developed in this paper. Fluorescein (FR), rhodamine B (RB), and magnetic powder (MP) were used as anti-counterfeiting labels. According to their different properties and the special seed pelleting process, four dual-labeling treatments were conducted for two tobacco varieties, MS Yunyan85 (MSYY85) and Honghua Dajinyuan (HHDJY). Then the seed germination and seedling growth status were investigated, and the fluorescence in cracked pellets and developing seedlings was observed under different excitation lights. The results showed that FR, RB, and MP had no negative effects on the germination, seedling growth, and MDA content of the pelleted seeds, and even some treatments significantly enhanced seedling dry weight, vigor index, and shoot height in MS YY85, and increased SOD activity and chlorophyll content in HHDJY as compared to the control. In addition, the cotyledon tip of seedlings treated with FR and MP together represented bright green fluorescence under illumination of blue light (478 nm). And the seedling cotyledon vein treated with RB and MP together showed red fluorescence under green light (546 nm). All seeds pelleted with magnetic powder of proper concentration could be attracted by a magnet. Thus, it indicated that those new dual-labeling methods that fluorescent compound and magnetic powder simultaneously applied in the same seed pellets definitely improved anti-counterfeiting technology and enhanced the seed security. This technology will ensure that high quality seed will be used in the crop production.

  7. Quantifying aquifer properties and freshwater resource in coastal barriers: a hydrogeophysical approach applied at Sasihithlu (Karnataka state, India

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    J.-M. Vouillamoz


    Full Text Available Many human communities living in coastal areas in Africa and Asia rely on thin freshwater lenses for their domestic supply. Population growth together with change in rainfall patterns and sea level will probably impact these vulnerable groundwater resources. Spatial knowledge of the aquifer properties and creation of a groundwater model are required for achieving a sustainable management of the resource. This paper presents a ready-to-use methodology for estimating the key aquifer properties and the freshwater resource based on the joint use of two non-invasive geophysical tools together with common hydrological measurements.

    We applied the proposed methodology in an unconfined aquifer of a coastal sandy barrier in South-Western India. We jointly used magnetic resonance and transient electromagnetic soundings and we monitored rainfall, groundwater level and groundwater electrical conductivity. The combined interpretation of geophysical and hydrological results allowed estimating the aquifer properties and mapping the freshwater lens. Depending on the location and season, we estimate the freshwater reserve to range between 400 and 700 L m−2 of surface area (± 50%. We also estimate the recharge using time lapse geophysical measurements with hydrological monitoring. After a rainy event close to 100% of the rain is reaching the water table, but the net recharge at the end of the monsoon is less than 10% of the rain. Thus, we conclude that a change in rainfall patterns will probably not impact the groundwater resource since most of the rain water recharging the aquifer is flowing towards the sea and the river. However, a change in sea level will impact both the groundwater reserve and net recharge.

  8. Applying an ecosystem service approach to unravel links between ecosystems and society in the coast of central Chile. (United States)

    de Juan, Silvia; Gelcich, Stefan; Ospina-Alvarez, Andres; Perez-Matus, Alejandro; Fernandez, Miriam


    Ecosystem-based management implies understanding feedbacks between ecosystems and society. Such understanding can be approached with the Drivers-Pressures-State change-Impacts-Response framework (DPSIR), incorporating stakeholders' preferences for ecosystem services to assess impacts on society. This framework was adapted to six locations in the central coast of Chile, where artisanal fisheries coexist with an increasing influx of tourists, and a set of fisheries management areas alternate with open access areas and a no-take Marine Protected Area (MPA). The ecosystem services in the study area were quantified using biomass and species richness in intertidal and subtidal areas as biological indicators. The demand for ecosystem services was elicited by interviews to the principal groups of users. Our results evidenced decreasing landings and a negative perception of fishermen on temporal trends of catches. The occurrence of recreational fishing was negligible, although the consumption of seafood by tourists was relatively high. Nevertheless, the consumption of organisms associated to the study system was low, which could be linked, amongst other factors, to decreasing catches. The comparison of biological indicators between management regimens provided variable results, but a positive effect of management areas and the MPA on some of the metrics was observed. The prioritising of ecosystem attributes by tourists was highly homogenous across the six locations, with "scenic beauty" consistently selected as the preferred attribute, followed by "diversity". The DPSIR framework illustrated the complex interactions existing in these locations, with weak linkages between society's priorities, existing management objectives and the state of biological communities. Overall, this work improved our knowledge on relations between components of coastal areas in central Chile, of paramount importance to advance towards an ecosystem-based management in the area.

  9. Applying the system engineering approach to devise a master’s degree program in space technology in developing countries (United States)

    Jazebizadeh, Hooman; Tabeshian, Maryam; Taheran Vernoosfaderani, Mahsa


    Although more than half a century is passed since space technology was first developed, developing countries are just beginning to enter the arena, focusing mainly on educating professionals. Space technology by itself is an interdisciplinary science, is costly, and developing at a fast pace. Moreover, a fruitful education system needs to remain dynamic if the quality of education is the main concern, making it a complicated system. This paper makes use of the System Engineering Approach and the experiences of developed countries in this area while incorporating the needs of the developing countries to devise a comprehensive program in space engineering at the Master's level. The needs of the developing countries as regards space technology education may broadly be put into two categories: to raise their knowledge of space technology which requires hard work and teamwork skills, and to transfer and domesticate space technology while minimizing the costs and maximizing its effectiveness. The requirements of such space education system, which include research facilities, courses, and student projects are then defined using a model drawn from the space education systems in universities in North America and Europe that has been modified to include the above-mentioned needs. Three design concepts have been considered and synthesized through functional analysis. The first one is Modular and Detail Study which helps students specialize in a particular area in space technology. Second is referred to as Integrated and Interdisciplinary Study which focuses on understanding and development of space systems. Finally, the third concept which has been chosen for the purpose of this study, is a combination of the other two, categorizing the required curriculum into seven modules, setting aside space applications. This helps students to not only specialize in one of these modules but also to get hands-on experience in a real space project through participation in summer group

  10. Applying an Inverse Model to Estimate Ammonia Emissions at Cattle Feedlots Using Three Different Observation-Based Approaches (United States)

    Shonkwiler, K. B.; Ham, J. M.; Nash, C.


    from the inverse model (FIDES) using all three datasets will be compared to emissions from the bLS model (WindTrax) using only high speed data (laser; CRDS). Results may lend further validity to the conditional sampler approach for more easily and accurately monitoring NH3 fluxes from CAFOs and other strong areal sources.

  11. A study on the Abruzzo 6 April 2009 earthquake by applying the RST approach to 15 years of AVHRR TIR observations

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    M. Lisi


    Full Text Available A self adaptive approach (RST, Robust Satellite Technique has been proposed as a suitable tool for satellite TIR surveys in seismically active regions devoted to detect and monitor thermal anomalies possibly related to earthquake occurrence. In this work, RST approach has been applied to 15 years of AVHRR (Advanced Very High Resolution Radiometer thermal infrared observations in order to study the 6 April 2009 Abruzzo earthquake. Preliminary results show clear differences in TIR anomalies occurrence during the periods used for validation (15 March–15 April 2009 and the one (15 March–15 April 2008 without earthquakes with ML≥4.5, used for confutation purposes. Quite clear TIR anomalies appears also to mark main tectonic lineaments during the preparatory phases of others, low magnitude(3.9<ML<4.6 earthquakes, occurred in the area in the same period.

  12. User-centered Development of Video telephony for Servicing Mainly Older Users: Review and Evaluation of an Approach Applied for 10 Years

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    Seppo Väyrynen


    Full Text Available A research and development (R&D approach has been applied to video telephony (VT in northern Finland since 1994 by broad consortia. The focus has been on the considerable involvement of ergonomics within the engineering and implementation of VT. This multidisciplinary participatory ergonomic R&D approach (PERDA is described briefly, in general and through two cases. The user-centeredness should be discernible in this sociotechnical systemic entity. A consortium—comprising mainly manufacturers, individual and organizational users of technological products, and R&D organizations—serves as a natural context for product development. VT has been considered to have much potential for enhancing (multimedia interaction and effective multimodal communication, thereby facilitating many activities of everyday life and work. An assessment of the VT system, called HomeHelper, involved older citizens, as clients or customers, and the staff of social, health, and other services.

  13. Applying Aspects of the Expert Performance Approach to Better Understand the Structure of Skill and Mechanisms of Skill Acquisition in Video Games. (United States)

    Boot, Walter R; Sumner, Anna; Towne, Tyler J; Rodriguez, Paola; Anders Ericsson, K


    Video games are ideal platforms for the study of skill acquisition for a variety of reasons. However, our understanding of the development of skill and the cognitive representations that support skilled performance can be limited by a focus on game scores. We present an alternative approach to the study of skill acquisition in video games based on the tools of the Expert Performance Approach. Our investigation was motivated by a detailed analysis of the behaviors responsible for the superior performance of one of the highest scoring players of the video game Space Fortress (Towne, Boot, & Ericsson, ). This analysis revealed how certain behaviors contributed to his exceptional performance. In this study, we recruited a participant for a similar training regimen, but we collected concurrent and retrospective verbal protocol data throughout training. Protocol analysis revealed insights into strategies, errors, mental representations, and shifting game priorities. We argue that these insights into the developing representations that guided skilled performance could only easily have been derived from the tools of the Expert Performance Approach. We propose that the described approach could be applied to understand performance and skill acquisition in many different video games (and other short- to medium-term skill acquisition paradigms) and help reveal mechanisms of transfer from gameplay to other measures of laboratory and real-world performance.

  14. Computational approach to estimating the effects of blood properties on changes in intra-stent flow. (United States)

    Benard, Nicolas; Perrault, Robert; Coisne, Damien


    In this study various blood rheological assumptions are numerically investigated for the hemodynamic properties of intra-stent flow. Non-newtonian blood properties have never been implemented in blood coronary stented flow investigation, although its effects appear essential for a correct estimation and distribution of wall shear stress (WSS) exerted by the fluid on the internal vessel surface. Our numerical model is based on a full 3D stent mesh. Rigid wall and stationary inflow conditions are applied. Newtonian behavior, non-newtonian model based on Carreau-Yasuda relation and a characteristic newtonian value defined with flow representative parameters are introduced in this research. Non-newtonian flow generates an alteration of near wall viscosity norms compared to newtonian. Maximal WSS values are located in the center part of stent pattern structure and minimal values are focused on the proximal stent wire surface. A flow rate increase emphasizes fluid perturbations, and generates a WSS rise except for interstrut area. Nevertheless, a local quantitative analysis discloses an underestimation of WSS for modelisation using a newtonian blood flow, with clinical consequence of overestimate restenosis risk area. Characteristic viscosity introduction appears to present a useful option compared to rheological modelisation based on experimental data, with computer time gain and relevant results for quantitative and qualitative WSS determination.

  15. Modelisation de photodetecteurs a base de matrices de diodes avalanche monophotoniques pour tomographie d'emission par positrons (United States)

    Corbeil Therrien, Audrey

    La tomographie d'emission par positrons (TEP) est un outil precieux en recherche preclinique et pour le diagnostic medical. Cette technique permet d'obtenir une image quantitative de fonctions metaboliques specifiques par la detection de photons d'annihilation. La detection des ces photons se fait a l'aide de deux composantes. D'abord, un scintillateur convertit l'energie du photon 511 keV en photons du spectre visible. Ensuite, un photodetecteur convertit l'energie lumineuse en signal electrique. Recemment, les photodiodes avalanche monophotoniques (PAMP) disposees en matrice suscitent beaucoup d'interet pour la TEP. Ces matrices forment des detecteurs sensibles, robustes, compacts et avec une resolution en temps hors pair. Ces qualites en font un photodetecteur prometteur pour la TEP, mais il faut optimiser les parametres de la matrice et de l'electronique de lecture afin d'atteindre les performances optimales pour la TEP. L'optimisation de la matrice devient rapidement une operation difficile, car les differents parametres interagissent de maniere complexe avec les processus d'avalanche et de generation de bruit. Enfin, l'electronique de lecture pour les matrices de PAMP demeure encore rudimentaire et il serait profitable d'analyser differentes strategies de lecture. Pour repondre a cette question, la solution la plus economique est d'utiliser un simulateur pour converger vers la configuration donnant les meilleures performances. Les travaux de ce memoire presentent le developpement d'un tel simulateur. Celui-ci modelise le comportement d'une matrice de PAMP en se basant sur les equations de physique des semiconducteurs et des modeles probabilistes. Il inclut les trois principales sources de bruit, soit le bruit thermique, les declenchements intempestifs correles et la diaphonie optique. Le simulateur permet aussi de tester et de comparer de nouvelles approches pour l'electronique de lecture plus adaptees a ce type de detecteur. Au final, le simulateur vise a

  16. A practical and applied approach to assessing the cross cutting nature of child injury prevention as a basis for policy making at the local level

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    Beatrice Scholtes


    Full Text Available Aim: Risk factors for child injury are multi-faceted. Social, environmental and economic factors place responsibility for prevention upon many stakeholders across traditional sectors such as health, justice, environment and education. Multi-sectoral collaboration for injury prevention is thus essential. In addition, co-benefits due to injury prevention initiatives exist. However, multi-sectoral collaboration is often difficult to establish and maintain. We present an applied approach for practitioners and policy makers at the local level to use to explore and address the multi-sectoral nature of child injury. Methods: We combined elements of the Haddon Matrix and the Lens and Telescope model, to develop a new approach for practitioners and policy makers at the local level. Results: The approach offers the opportunity for diverse sectors at the local level to work together to identify their role in child injury prevention. Based on ecological injury prevention and life-course epidemiology it encourages multi-disciplinary team building from the outset. The process has three phases: first, visualising the multi-sectoral responsibilities for child injury prevention in the local area; second,  demonstrating the need for multi-sectoral collaboration and helping plan prevention activities together; and third, visualising potential co-benefits to other sectors and age groups that may arise from child injury prevention initiatives. Conclusion: The approach and process encourages inter-sectoral collaboration for child injury prevention at the local level. It is a useful addition for child injury  prevention at the local level, however testing the practicality of the approach in a real-world setting, and refinement of the process would improve it further.

  17. Security planning an applied approach

    CERN Document Server

    Lincke, Susan


    This book guides readers through building an IT security plan. Offering a template, it helps readers to prioritize risks, conform to regulation, plan their defense and secure proprietary/confidential information. The process is documented in the supplemental online security workbook. Security Planning is designed for the busy IT practitioner, who does not have time to become a security expert, but needs a security plan now. It also serves to educate the reader of a broader set of concepts related to the security environment through the Introductory Concepts and Advanced sections. The book serv

  18. Research Approaches in Applied Linguistics

    Institute of Scientific and Technical Information of China (English)




  19. A Hybrid Approach Using an Artificial Bee Algorithm with Mixed Integer Programming Applied to a Large-Scale Capacitated Facility Location Problem

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    Guillermo Cabrera G.


    Full Text Available We present a hybridization of two different approaches applied to the well-known Capacitated Facility Location Problem (CFLP. The Artificial Bee algorithm (BA is used to select a promising subset of locations (warehouses which are solely included in the Mixed Integer Programming (MIP model. Next, the algorithm solves the subproblem by considering the entire set of customers. The hybrid implementation allows us to bypass certain inherited weaknesses of each algorithm, which means that we are able to find an optimal solution in an acceptable computational time. In this paper we demonstrate that BA can be significantly improved by use of the MIP algorithm. At the same time, our hybrid implementation allows the MIP algorithm to reach the optimal solution in a considerably shorter time than is needed to solve the model using the entire dataset directly within the model. Our hybrid approach outperforms the results obtained by each technique separately. It is able to find the optimal solution in a shorter time than each technique on its own, and the results are highly competitive with the state-of-the-art in large-scale optimization. Furthermore, according to our results, combining the BA with a mathematical programming approach appears to be an interesting research area in combinatorial optimization.

  20. Conceptual Modeling (CM) for Military Modeling and Simulation (M&S) (Modelisation conceptuelle (MC) pour la modelisation et la simulation (M&S) militaires) (United States)


    The total spectrum of R&T activities is covered by the following 7 bodies: • AVT Applied Vehicle Technology Panel • HFM Human Factors and Medicine ...Amherst, NY, USA: Prometheus Books. ANNEX K – BIBLIOGRAPHY K - 12 RTO-TR-MSG-058 [179] Lozano, M.G., V. Mojtahed and B. Andersson. 2003. “Using a

  1. Performance of the 'material Failure Forecast Method' in real-time situations: A Bayesian approach applied on effusive and explosive eruptions (United States)

    Boué, A.; Lesage, P.; Cortés, G.; Valette, B.; Reyes-Dávila, G.; Arámbula-Mendoza, R.; Budi-Santoso, A.


    Most attempts of deterministic eruption forecasting are based on the material Failure Forecast Method (FFM). This method assumes that a precursory observable, such as the rate of seismic activity, can be described by a simple power law which presents a singularity at a time close to the eruption onset. Until now, this method has been applied only in a small number of cases, generally for forecasts in hindsight. In this paper, a rigorous Bayesian approach of the FFM designed for real-time applications is applied. Using an automatic recognition system, seismo-volcanic events are detected and classified according to their physical mechanism and time series of probability distributions of the rates of events are calculated. At each time of observation, a Bayesian inversion provides estimations of the exponent of the power law and of the time of eruption, together with their probability density functions. Two criteria are defined in order to evaluate the quality and reliability of the forecasts. Our automated procedure has allowed the analysis of long, continuous seismic time series: 13 years from Volcán de Colima, Mexico, 10 years from Piton de la Fournaise, Reunion Island, France, and several months from Merapi volcano, Java, Indonesia. The new forecasting approach has been applied to 64 pre-eruptive sequences which present various types of dominant seismic activity (volcano-tectonic or long-period events) and patterns of seismicity with different level of complexity. This has allowed us to test the FFM assumptions, to determine in which conditions the method can be applied, and to quantify the success rate of the forecasts. 62% of the precursory sequences analysed are suitable for the application of FFM and half of the total number of eruptions are successfully forecast in hindsight. In real-time, the method allows for the successful forecast of 36% of all the eruptions considered. Nevertheless, real-time forecasts are successful for 83% of the cases that fulfil the

  2. Quantitative versus qualitative approaches: a comparison of two research methods applied to identification of key health issues for working horses in Lesotho. (United States)

    Upjohn, M M; Attwood, G A; Lerotholi, T; Pfeiffer, D U; Verheyen, K L P


    The relative merits and potential complementarity of participatory methods and classical epidemiological techniques in veterinary-related research is a current topic of discussion. Few reported studies have applied both methodologies within the same research framework to enable direct comparison. The aim of this study was to compare issues identified by a classical epidemiological study of horses and their owners with those identified by owner communities using participatory approaches. In 2009, a cross-sectional survey was undertaken as part of an impact assessment study of farrier and saddler training programmes, and a small-scale nutrition trial, implemented in Lesotho by a UK-based equine charity. In total, 245 horses and their 237 owners participated in the survey which comprised a face-to-face structured questionnaire covering knowledge and practices relating to equine husbandry and primary healthcare, clinical examination and sampling of horses, and examination of tack used on those horses. In early 2010, 56 owners in three survey regions, some of whom participated in the survey, attended a participatory workshop. Each workshop group created a local resource map whilst discussing and identifying key issues associated with horse ownership and what might have an adverse impact on horse health and work. Following map completion, each group began by prioritising the identified issues, and then ranked them using a pairwise/ranking matrix to reflect how important issues were in relation to each other. Overall priority issues were: mouth problems, hunger and nutrition, diseases (including infectious diseases, parasites and colic), husbandry (including wound management), and feet and limb problems. Major health issues identified by cross-sectional study included sharp enamel points on teeth, endo- and ectoparasite infestation, suboptimal nutrition, tack-associated wounds, overgrown and poorly balanced feet and poor owner husbandry knowledge and practices. Whilst

  3. ChIP-enriched in silico targets (ChEST), a ChIP-on-chip approach applied to analyzing skeletal muscle genes. (United States)

    Junion, Guillaume; Jagla, Krzysztof


    Mapping the cis-regulatory modules (CRMs) to which bind myogenic transcription factors is an -obligatory step towards understanding gene regulatory networks governing muscle development and function. This can be achieved in silico or by chromatin immunoprecipitation (ChIP) approaches. We have developed a ChIP-enriched in silico targets (ChEST) strategy designed for mapping the CRMs by combining in silico and ChIP methods. ChEST involves a software-assisted prediction of transcription factor (TF) - specific CRMs, which are spotted to produce a computed genomic CRM microarray. In parallel, the in vivo pool of targets of a given TF is isolated by ChIP and used as a probe for hybridization with the array generated. Here we describe ChEST strategy applied to identify direct targets of Myogenic Enhancer Factor, Dmef2 in Drosophila embryos.

  4. Pro/E课程的教学改革研究%The Application of Case Teaching Approach in Pro/E Applied Technology Teaching

    Institute of Scientific and Technical Information of China (English)

    王蕊; 雷康


    The application of case teaching approach in Pro/E applied technology teaching can help students actively participate in the teaching activity, which shows the leading position of the students in the classroom. The discussion of modeling approach of the actual spare part can reinforce students' autonomous study and improve their ability to combine theory with practice. What's more, it can promote the teaching effect of Pro/E software so as to realize the goal of putting what is learnt into practice.%在Pro/E软件教学中,力争在机房授课的同时改变传统的教学方法与考核方式,运用案例教学法,使学生积极参与教学活动,激发学生学习兴趣,培养学生学习的主动性.通过对实体零件建模方法的分析讨论,培养学生自主学习、理论联系实际的能力,并达到提高Pro/E软件的教学质量和教学效果的目的,真正做到学以致用.

  5. From basic physics to mechanisms of toxicity: the "liquid drop" approach applied to develop predictive classification models for toxicity of metal oxide nanoparticles. (United States)

    Sizochenko, Natalia; Rasulev, Bakhtiyor; Gajewicz, Agnieszka; Kuz'min, Victor; Puzyn, Tomasz; Leszczynski, Jerzy


    Many metal oxide nanoparticles are able to cause persistent stress to live organisms, including humans, when discharged to the environment. To understand the mechanism of metal oxide nanoparticles' toxicity and reduce the number of experiments, the development of predictive toxicity models is important. In this study, performed on a series of nanoparticles, the comparative quantitative-structure activity relationship (nano-QSAR) analyses of their toxicity towards E. coli and HaCaT cells were established. A new approach for representation of nanoparticles' structure is presented. For description of the supramolecular structure of nanoparticles the "liquid drop" model was applied. It is expected that a novel, proposed approach could be of general use for predictions related to nanomaterials. In addition, in our study fragmental simplex descriptors and several ligand-metal binding characteristics were calculated. The developed nano-QSAR models were validated and reliably predict the toxicity of all studied metal oxide nanoparticles. Based on the comparative analysis of contributed properties in both models the LDM-based descriptors were revealed to have an almost similar level of contribution to toxicity in both cases, while other parameters (van der Waals interactions, electronegativity and metal-ligand binding characteristics) have unequal contribution levels. In addition, the models developed here suggest different mechanisms of nanotoxicity for these two types of cells.

  6. Ground observations and remote sensing data for integrated modelisation of water budget in the Merguellil catchment, Tunisia (United States)

    Mougenot, Bernard


    The Mediterranean region is affected by water scarcity. Some countries as Tunisia reached the limit of 550 m3/year/capita due overexploitation of low water resources for irrigation, domestic uses and industry. A lot of programs aim to evaluate strategies to improve water consumption at regional level. In central Tunisia, on the Merguellil catchment, we develop integrated water resources modelisations based on social investigations, ground observations and remote sensing data. The main objective is to close the water budget at regional level and to estimate irrigation and water pumping to test scenarios with endusers. Our works benefit from French, bilateral and European projects (ANR, MISTRALS/SICMed, FP6, FP7…), GMES/GEOLAND-ESA) and also network projects as JECAM and AERONET, where the Merguellil site is a reference. This site has specific characteristics associating irrigated and rainfed crops mixing cereals, market gardening and orchards and will be proposed as a new environmental observing system connected to the OMERE, TENSIFT and OSR systems respectively in Tunisia, Morocco and France. We show here an original and large set of ground and remote sensing data mainly acquired from 2008 to present to be used for calibration/validation of water budget processes and integrated models for present and scenarios: - Ground data: meteorological stations, water budget at local scale: fluxes tower, soil fluxes, soil and surface temperature, soil moisture, drainage, flow, water level in lakes, aquifer, vegetation parameters on selected fieds/month (LAI, height, biomass, yield), land cover: 3 times/year, bare soil roughness, irrigation and pumping estimations, soil texture. - Remote sensing data: remote sensing products from multi-platform (MODIS, SPOT, LANDSAT, ASTER, PLEIADES, ASAR, COSMO-SkyMed, TerraSAR X…), multi-wavelength (solar, micro-wave and thermal) and multi-resolution (0.5 meters to 1 km). Ground observations are used (1) to calibrate soil

  7. From basic physics to mechanisms of toxicity: the ``liquid drop'' approach applied to develop predictive classification models for toxicity of metal oxide nanoparticles (United States)

    Sizochenko, Natalia; Rasulev, Bakhtiyor; Gajewicz, Agnieszka; Kuz'min, Victor; Puzyn, Tomasz; Leszczynski, Jerzy


    Many metal oxide nanoparticles are able to cause persistent stress to live organisms, including humans, when discharged to the environment. To understand the mechanism of metal oxide nanoparticles' toxicity and reduce the number of experiments, the development of predictive toxicity models is important. In this study, performed on a series of nanoparticles, the comparative quantitative-structure activity relationship (nano-QSAR) analyses of their toxicity towards E. coli and HaCaT cells were established. A new approach for representation of nanoparticles' structure is presented. For description of the supramolecular structure of nanoparticles the ``liquid drop'' model was applied. It is expected that a novel, proposed approach could be of general use for predictions related to nanomaterials. In addition, in our study fragmental simplex descriptors and several ligand-metal binding characteristics were calculated. The developed nano-QSAR models were validated and reliably predict the toxicity of all studied metal oxide nanoparticles. Based on the comparative analysis of contributed properties in both models the LDM-based descriptors were revealed to have an almost similar level of contribution to toxicity in both cases, while other parameters (van der Waals interactions, electronegativity and metal-ligand binding characteristics) have unequal contribution levels. In addition, the models developed here suggest different mechanisms of nanotoxicity for these two types of cells.Many metal oxide nanoparticles are able to cause persistent stress to live organisms, including humans, when discharged to the environment. To understand the mechanism of metal oxide nanoparticles' toxicity and reduce the number of experiments, the development of predictive toxicity models is important. In this study, performed on a series of nanoparticles, the comparative quantitative-structure activity relationship (nano-QSAR) analyses of their toxicity towards E. coli and HaCaT cells were

  8. How to Apply Critical Thinking Approach in Accounting Teaching%批判思考教学法在会计教学中的应用

    Institute of Scientific and Technical Information of China (English)



    Traditional accounting teaching lays less emphasis on improving students’ critical thinking skill. In order to cultivate students’ critical thinking skill, it is necessary to combine theory and practice and apply critical thinking in accounting teaching. Critical thinking approach is not new. It is just the adjustment of teaching attitude, emphasizing on students’ orientation. It is based on asking and answering, as well as discussing. It can be achieved if teachers’ worries and doubt are reduced.%以往的会计教学忽视提高学生的思辨、批判思考能力。将批判思考教学应用于会计教学,必须理论与实际相结合。批判思考教学法并非新的教学方法,而是在现有的教学法基础上,强调以学生为主的教学方式。以常见的问答法、讨论法为教学主轴,降低一般教师对批判思考教学法的疑虑,这样培养学生的批判思考能力才不会论为批判思考教学法空谈。

  9. Evaluating tidal marsh sustainability in the face of sea-level rise: a hybrid modeling approach applied to San Francisco Bay.

    Directory of Open Access Journals (Sweden)

    Diana Stralberg

    Full Text Available BACKGROUND: Tidal marshes will be threatened by increasing rates of sea-level rise (SLR over the next century. Managers seek guidance on whether existing and restored marshes will be resilient under a range of potential future conditions, and on prioritizing marsh restoration and conservation activities. METHODOLOGY: Building upon established models, we developed a hybrid approach that involves a mechanistic treatment of marsh accretion dynamics and incorporates spatial variation at a scale relevant for conservation and restoration decision-making. We applied this model to San Francisco Bay, using best-available elevation data and estimates of sediment supply and organic matter accumulation developed for 15 Bay subregions. Accretion models were run over 100 years for 70 combinations of starting elevation, mineral sediment, organic matter, and SLR assumptions. Results were applied spatially to evaluate eight Bay-wide climate change scenarios. PRINCIPAL FINDINGS: Model results indicated that under a high rate of SLR (1.65 m/century, short-term restoration of diked subtidal baylands to mid marsh elevations (-0.2 m MHHW could be achieved over the next century with sediment concentrations greater than 200 mg/L. However, suspended sediment concentrations greater than 300 mg/L would be required for 100-year mid marsh sustainability (i.e., no elevation loss. Organic matter accumulation had minimal impacts on this threshold. Bay-wide projections of marsh habitat area varied substantially, depending primarily on SLR and sediment assumptions. Across all scenarios, however, the model projected a shift in the mix of intertidal habitats, with a loss of high marsh and gains in low marsh and mudflats. CONCLUSIONS/SIGNIFICANCE: Results suggest a bleak prognosis for long-term natural tidal marsh sustainability under a high-SLR scenario. To minimize marsh loss, we recommend conserving adjacent uplands for marsh migration, redistributing dredged sediment to raise

  10. Optical excitation and electron relaxation dynamics at semiconductor surfaces: a combined approach of density functional and density matrix theory applied to the silicon (001) surface

    Energy Technology Data Exchange (ETDEWEB)

    Buecking, N.


    In this work a new theoretical formalism is introduced in order to simulate the phononinduced relaxation of a non-equilibrium distribution to equilibrium at a semiconductor surface numerically. The non-equilibrium distribution is effected by an optical excitation. The approach in this thesis is to link two conventional, but approved methods to a new, more global description: while semiconductor surfaces can be investigated accurately by density-functional theory, the dynamical processes in semiconductor heterostructures are successfully described by density matrix theory. In this work, the parameters for density-matrix theory are determined from the results of density-functional calculations. This work is organized in two parts. In Part I, the general fundamentals of the theory are elaborated, covering the fundamentals of canonical quantizations as well as the theory of density-functional and density-matrix theory in 2{sup nd} order Born approximation. While the formalism of density functional theory for structure investigation has been established for a long time and many different codes exist, the requirements for density matrix formalism concerning the geometry and the number of implemented bands exceed the usual possibilities of the existing code in this field. A special attention is therefore attributed to the development of extensions to existing formulations of this theory, where geometrical and fundamental symmetries of the structure and the equations are used. In Part II, the newly developed formalism is applied to a silicon (001)surface in a 2 x 1 reconstruction. As first step, density-functional calculations using the LDA functional are completed, from which the Kohn-Sham-wave functions and eigenvalues are used to calculate interaction matrix elements for the electron-phonon-coupling an the optical excitation. These matrix elements are determined for the optical transitions from valence to conduction bands and for electron-phonon processes inside the

  11. A new approach to the assessment of flooding and dampness hazards in cultural heritage, applied to the historic centre of Seville (Spain). (United States)

    Ortiz, Rocío; Ortiz, Pilar; Martín, José María; Vázquez, María Auxiliadora


    Flooding and dampness have caused considerable damage to historic towns and cities and have become more frequent in recent years. The aim of this paper is to analyse the hazards of flooding and dampness in historic cities to establish a methodology that prioritises preventive conservation actions and restorations. The case study concerns the historic centre of Seville (Spain) and parish churches built between the 13th and 18th centuries. Geographic information system (GIS) software has been used to assess hazards caused by flooding and dampness along with a Delphi consultation process surveying a multidisciplinary group of seven experts-archaeologists, geologists, chemists, architects, engineers and environmentalists-to gain a general overview of the hazards affecting each area of the city. Currently, the historic centre of Seville is at a very low risk of flooding due to the engineering works being undertaken to divert the river course. For flooding to occur, water levels would need to rise over 6 to 12m along the different sections of the defensive walls; as a result, the historic centre has not been flooded since 1961, when these defences broke. However, there is a continual presence of dampness due to the proximity of the river, the presence of underground water and the permeability of the subsoil, resulting in continual damage to the lower sections of the monuments studied. Hence, hazard maps of flooding and dampness need to be dovetailed. This new approach provides tools for decision-makers in the current crisis, allowing them to prioritise strategies that will minimise damage in a town, as the urban unit where territorial policies could be applied.

  12. Evaluating the suitability of Hydrobia ulvae as a test species for sediment metal toxicity testing applying a tissue residue approach to metal mixtures in laboratory and field exposures. (United States)

    Campana, Olivia; Rodríguez, Antonio; Blasco, Julián


    A major weakness in evaluating the suitability of a biomonitor organism is the poor ability to predict the variability of the bioavailability of metals from measured environmental concentrations. In this study, the intertidal gastropod Hydrobia ulvae was used to evaluate its suitability as a test organism for assessing sediment metal toxicity. Toxicity tests were run with sediments spiked with copper, cadmium and zinc applied both as single metal and as a mixture to investigate toxicological interactions evaluating different lethal and sublethal effects. Dose-response relationships were constructed based both on tissue residue approach and particulate metal concentrations. Because metal-spiked sediments used in routine toxicity tests often do not exhibit the same adsorption/desorption kinetics as the natural sediments, the laboratory results were compared to 10-d bioassays conducted with natural field sediments collected from the Guadalete estuary (SW Spain). Highly significant correlations between tissue residue concentrations and particulate metal concentrations were found for all metal-spiked or field-collected and demonstrated that: (i) H. ulvae readily accumulated copper and cadmium in response to contamination and (ii) dietary uptake was determined to be the most significant route of metal exposure. The comparison of the modeled tissue residue-response curve developed from the mixture tests was in good agreement with the results from the bioassay conducted with field sediments and strongly demonstrated that H. ulvae is also a suitable test organism for assessing copper sediment toxicity. In contrast, the dose-response curve expressed as a function of total particulate metal concentrations would fail in predicting effect, erroneously assessing higher metal toxicity.

  13. 现代产品设计中竹材的应用方法初探%The Approaches to Apply Bamboo in Modern Product Design

    Institute of Scientific and Technical Information of China (English)



    In this study, a site survey was conducted to investigate on the bamboo product market, the traditional and modern bamboo processing technology. Some excellent modern bamboo product designs were reorganized and sorted. From the point view of material selection,the relationship between bamboo individual difference and utilization rate in modern product design was analyzed. It was suggested that bamboo should be mixed with other materials to overcome the insufficiencies in structure, function and aesthetics. The approaches to apply various bamboo materials were discussed from the perspectives of point, line, surface and volume. Finally, the process to design modern bamboo products was demonstrated by a set of tables and chairs made of bamboo-board.%通过对竹制品市场状况、传统和现代的竹材加工工艺进行了现场调研,并将收集到的现代优秀竹材产品设计资料进行了分类整理;从材料选择角度分析了现代产品设计中竹材个体差异与使用率的关系,提出竹材需要与其他材料进行合理搭配以解决结构、功能和审美问题,并从点、线、面、体这4大造型元素角度分析、归纳了各类竹材的运用方式;最后通过竹板材餐桌椅的设计实践展示了现代竹材产品的设计过程.

  14. Ageing of palladium tritide: mechanical characterization, helium state and modelling; Vieillissement du tritiure de palladium: caracterisation mecanique, etat de l'helium et modelisation

    Energy Technology Data Exchange (ETDEWEB)

    Segard, M.


    Palladium is commonly used for the storage of tritium (the hydrogen radioactive isotope), since it forms a low-equilibrium-pressure and reversible tritide. Tritium decay into helium-3 is responsible for the ageing of the tritide, leading to the apparition of helium-3 bubbles for instance. Both experimental and theoretical aspects of this phenomenon are studied here.Previous works on ageing modelling led to two main models, dealing with:- Helium-3 bubbles nucleation (using a cellular automaton), - Bubbles growth (using continuum mechanics).These models were quite efficient, but their use was limited by the lack of input data and fitting experimental parameters.To get through these limitations, this work has consisted in studying the most relevant experimental data to improve the modelling of the palladium tritide ageing.The first part of this work was focused on the assessment of the mechanical properties of the palladium tritide (yield strength, ultimate strength, mechanical behaviour). They were deduced from the in situ tensile tests performed on palladium hydride and deuteride. In the second part, ageing characterization was undertaken, mainly focusing on: - Bubbles observations in palladium tritide using transmission electron microscopy, - Internal bubble pressure measurements using nuclear magnetic resonance, - Macroscopic swelling measurements using pycno-metry.The present work has led to significant progress in ageing understanding and has brought very valuable improvements to the modelling of such a phenomenon. (author) [French] Le palladium est couramment utilise pour le stockage du tritium, isotope radioactif de l'hydrogEne, car il forme un tritiure reversible, A basse pression d'equilibre. La decroissance du tritium en helium-3 provoque un vieillissement du tritiure, caracterise notamment par l'apparition de bulles d'helium-3, qui est etudie ici. De precedents travaux de modelisation du vieillissement avaient abouti a la creation de

  15. Etude de la transmission sonore a travers un protecteur de type "coquilles" : modelisation numerique et validation experimentale (United States)

    Boyer, Sylvain

    methode des seuils auditifs REAT (Real Ear Attenuation Threshold) aussi vu comme un "golden standard" est utilise pour quantifier la reduction du bruit mais surestime generalement la performance des protecteurs. Les techniques de mesure terrains, telles que la F-MIRE (Field Measurement in Real Ear) peuvent etre a l'avenir de meilleurs outils pour evaluer l'attenuation individuelle. Si ces techniques existent pour des bouchons d'oreilles, elles doivent etre adaptees et ameliorees pour le cas des coquilles, en determinant l'emplacement optimal des capteurs acoustiques et les facteurs de compensation individuels qui lient la mesure microphonique a la mesure qui aurait ete prise au tympan. La troisieme problematique specifique est l'optimisation de l'attenuation des coquilles pour les adapter a l'individu et a son environnement de travail. En effet, le design des coquilles est generalement base sur des concepts empiriques et des methodes essais/erreurs sur des prototypes. La piste des outils predictifs a ete tres peu etudiee jusqu'a present et meriterait d'etre approfondie. L'utilisation du prototypage virtuel, permettrait a la fois d'optimiser le design avant production, d'accelerer la phase de developpement produit et d'en reduire les couts. L'objectif general de cette these est de repondre a ces differentes problematiques par le developpement d'un modele de l'attenuation sonore d'un protecteur auditif de type coquille. A cause de la complexite de la geometrie de ces protecteurs, la methode principale de modelisation retenue a priori est la methode des elements finis (FEM). Pour atteindre cet objectif general, trois objectifs specifiques ont ete etablis et sont presentes dans les trois paragraphes suivants. (Abstract shortened by ProQuest.).

  16. Conception, instrumentation, modelisation et analyse d'un element de stockage d'energie par chaleur latente (United States)

    Millette, Jocelyn

    . Cette validation de la methode NTU-epsilon n'avait d'ailleurs jamais ete realisee et constituait, selon la litterature, un obstacle majeur a l'utilisation de cette methode dans un but de conception. L'element a une capacite d'environ 5 kWh. La paraffine P116, avant un point de fusion d'environ 47°C est utilisee comme MCP. Des mesures de temperature de l'air et du MCP a l'interieur de l'ESECL sont presentees afin de tracer un portrait global de l'ESECL lors du stockage et du destockage. La mesure de la puissance thermique lors du destockage est effectuee a l'aide d'un calorimetre construit selon la norme ANSI-ASHRAE 94.2. Des ameliorations et des commentaires sont appliques a cette norme. D'autres mesures auxiliaires sont aussi realisees. Une evolution typique de la temperature peut etre etablie. Les predictions du modele sont en bon accord avec les mesures experimentales. Ce modele est utilise afin de predire le comportement d'un ESECS typique. Ces predictions sont en bon accord avec les donnees experimentales tirees d'une autre etude. Cette modelisation d'un ESECS permet de comparer un ESECS et un ESECL de meme capacite et un ESECS et un ESECL de meme encombrement. Ces comparaisons permettent de suggerer un element de stockage hybride ou le stockage s'effectue a plus haute temperature (130°C), le MCP demeure solide et la capacite est d'environ 18 kWh. Les performances de cet element, tel que predites par le modele sont presentees.

  17. Materials and electromagnetism. The modeling of composite materials; Materiaux en electromagnetisme. Modelisation des materiaux composites

    Energy Technology Data Exchange (ETDEWEB)

    Priou, A. [Institut Universitaire de Technologie, 92 - Ville-d' Avray (France)


    Maxwell laws are briefly described and the different types of electromagnetic materials are presented. Composite materials are made up of at least 2 phases: a host phase and an inclusion. The inclusion is a discontinuous phase coming from a conducting material (metal, carbon based material, semi-conductor, solid electrolytes or conducting polymers) and is spread within the host phase either in an aleatory or organized way. The modeling of such media can be made by 3 different approaches. In the multi-diffusion approach, the size of the particles enclosed in the host material and their mutual interactions are taken into account. The quasi-static approach allows the definition of an equivalent medium in order to describe percolation phenomena. The approach based on cluster theory gives a complete mathematical description of composite materials. The modeling of dielectric-conducting multilayer is also presented. The last part of the article is dedicated to the characteristics and applications of chiral media and of last generation electromagnetic materials. (A.C.)

  18. Metaphor in applied linguistics: four cognitive approaches A metáfora na lingüística aplicada: quatro abordagens cognitivas

    Directory of Open Access Journals (Sweden)

    Gerard Steen


    Full Text Available This article presents some considerations into metaphor in language and thought- 'the topic and title of the first conference of its kind in Brazil'. The paper focuses on the discussions presented in the round table, which were mostly directed to the empirical research on metaphor in Applied Linguistics. This integrative and retrospective reflection on the papers presented will be conducted from the perspective of the debate into the relationship between metaphor in language and in thought. This central issue is at the core of my proposal for four different approaches to metaphor, based on the interdependence between language and thought as system and as use:1 metaphor in language as system; 2 metaphor in thought as system; 3 metaphor in language as use and 4 metaphor in thought as use. It is within the framework of these categories that metaphors should be studied, with a certain degree of autonomy, so that their interdependence can be better understood.Este artigo apresenta algumas considerações sobre a metáfora na língua e no pensamento - "o tópico e título da primeira conferência desse tipo no Brasil". Focaliza as discussões apresentadas nas falas da plenária, que são principalmente direcionadas para a pesquisa empírica sobre metáfora na Lingüística Aplicada. Esta reflexão retrospectiva que integra os trabalhos apresentados é conduzida a partir da perspectiva do debate sobre a relação entre metáfora na língua e no pensamento. Esta questão é central na minha proposta de quatro diferentes abordagens da metáfora, com base na interdependência entre língua e pensamento como sistema e como uso: 1 metáfora na língua como sistema; 2 metáfora no pensamento como sistema; 3 metáfora na língua em uso; 4 metáfora no pensamento em uso. A metáfora deveria ser estudada a partir dessas categorias, com um certo grau de autonomia, de modo que as sua interdependência possa ser melhor entendida.

  19. Applied superconductivity

    CERN Document Server

    Newhouse, Vernon L


    Applied Superconductivity, Volume II, is part of a two-volume series on applied superconductivity. The first volume dealt with electronic applications and radiation detection, and contains a chapter on liquid helium refrigeration. The present volume discusses magnets, electromechanical applications, accelerators, and microwave and rf devices. The book opens with a chapter on high-field superconducting magnets, covering applications and magnet design. Subsequent chapters discuss superconductive machinery such as superconductive bearings and motors; rf superconducting devices; and future prospec

  20. Modelisation Numerique De L'Interaction Sol-Structure Lors Du Phenomene De Fontis

    CERN Document Server

    Caudron, Matthieu; Heib, Marwan Al


    This article focuses on the simulation of soil-structure interaction during a sinkhole development by the use of a coupling numerical modelling approach. The 2D model uses a Finite Difference computer code associated with a Distinct Elements code to optimize the performances of both softwares. This allows an important decrease of computation time and the results computed are close of the experimental observations made before.

  1. Short term forecasting of petroleum product demand in France; Modelisation a court terme des consommations de produits petroliers en France

    Energy Technology Data Exchange (ETDEWEB)

    Cadren, M


    The analysis of petroleum product demand became a privileged thrust of research following the modifications in terms of structure and level of the petroleum markets since eighties. The greatest importance to econometrics models of Energy demand, joint works about nonstationary data, explained the development of error-correction models and the co-integration. In this context, the short term econometrics modelling of petroleum product demand does not only focus on forecasts but also on the measure of the gain acquired from using error-correction techniques and co-integration. It`s filling to take the influence of technical improvement and environment pressures into account in econometrics modelling of petroleum products demand. The first part presents the evolution of Energy Demand in France and more particularly the petroleum product demand since 1986. The objective is to determine the main characteristics of each product, which will help us to analyse and validate the econometrics models. The second part focus on the recent developments in times series modelling. We study the problem of nonstationary data and expose different unit root tests. We examine the main approaches to univariate and multivariate modelling with nonstationary data and distinguish the forecasts of the latter`s. The third part is intended to applications; its objective is to illustrate the theoretic developments of the second part with a comparison between the performances of different approaches (approach Box and Jenkins, Johansen approach`s and structural approach). The models will be applied to the main French petroleum market. The observed asymmetrical demand behaviour is also considered. (author) 153 refs.

  2. Mod\\'elisation multidomaine du comportement magn\\'eto-m\\'ecanique des aciers dual-phases

    CERN Document Server

    Mballa, Frederick Mballa; Lazreg, Said; Meilland, Philip


    The microstructure and mechanical behavior of dual-phase steels are highly sensitive to the variation of the process (heat treatments). Online control by magnetic method is relevant. A measurement under applied stress must be considered. The dual-phase is a two-phase medium (ferrite / martensite). Each phase can be considered as a sphere embedded in a homogeneous equivalent medium. The model used for each phase is based on a magneto-mechanical coupled model. This is an explicit single crystalline model representative of the behavior of the corresponding phase. Localization rules allow the simulation of the two-phases medium. Experiments and modeling are compared.

  3. Preventing Undesirable Effects of Mutual Trust and the Development of Skepticism in Virtual Groups by Applying the Knowledge and Information Awareness Approach (United States)

    Engelmann, Tanja; Kolodziej, Richard; Hesse, Friedrich W.


    Empirical studies have proven the effectiveness of the knowledge and information awareness approach of Engelmann and colleagues for improving collaboration and collaborative problem-solving performance of spatially distributed group members. This approach informs group members about both their collaborators' knowledge structures and their…

  4. North American paleoclimate reconstructions for the Last Glacial Maximum using an inverse modeling through iterative forward modeling approach applied to pollen data (United States)

    Izumi, Kenji; Bartlein, Patrick J.


    The inverse modeling through iterative forward modeling (IMIFM) approach was used to reconstruct Last Glacial Maximum (LGM) climates from North American fossil pollen data. The approach was validated using modern pollen data and observed climate data. While the large-scale LGM temperature IMIFM reconstructions are similar to those calculated using conventional statistical approaches, the reconstructions of moisture variables differ between the two approaches. We used two vegetation models, BIOME4 and BIOME5-beta, with the IMIFM approach to evaluate the effects on the LGM climate reconstruction of differences in water use efficiency, carbon use efficiency, and atmospheric CO2 concentrations. Although lower atmospheric CO2 concentrations influence pollen-based LGM moisture reconstructions, they do not significantly affect temperature reconstructions over most of North America. This study implies that the LGM climate was very cold but not very much drier than present over North America, which is inconsistent with previous studies.

  5. Motor fuel demand analysis - applied modelling in the European union; Modelisation de la demande de carburant appliquee a l`europe

    Energy Technology Data Exchange (ETDEWEB)

    Chorazewiez, S


    Motor fuel demand in Europe amounts to almost half of petroleum products consumption and to thirty percent of total final energy consumption. This study considers, Firstly, the energy policies of different European countries and the ways in which the consumption of motor gasoline and automotive gas oil has developed. Secondly it provides an abstract of demand models in the energy sector, illustrating their specific characteristics. Then it proposes an economic model of automotive fuel consumption, showing motor gasoline and automotive gas oil separately over a period of thirty years (1960-1993) for five main countries in the European Union. Finally, forecasts of consumption of gasoline and diesel up to the year 2020 are given for different scenarios. (author) 330 refs.

  6. Thermal modeling. Application to lithium batteries; Modelisation thermique. Application aux accumulateurs lithium

    Energy Technology Data Exchange (ETDEWEB)

    Alexandre, A. [Ecole Nationale Superieure de Mecanique et d`Aerotechnique (ENSMA), 86 - Poitiers (France); Flament, P. [SAFT, 33 - Bordeaux (France); Marolleau, T. [SAFT, Advanced and Industrial Battery Group, 86 - Poitiers (France); Guiot, T.; Lefriec, C. [TSR Futuropolis, 86 - Chasseneuil du Poitou (France)


    The thermal modeling of electrochemical batteries is today an integral part of the design and validation operations of new products. The Li-ion pair allows to increase the power density of batteries but leads to higher heat fluxes during charging-output cycles. Thus, the thermal control has become more crucial and requires the use of modeling. SAFT and TSR companies are involved in this approach and use the ESACAP software. This paper presents this software which uses a nodal method for the modeling of the coupled thermal and electrical processes that take place inside elementary cells and batteries. (J.S.)

  7. Mod\\'elisation et extraction de donn\\'ees pour un entrep\\^ot objet

    CERN Document Server

    Ravat, Franck; Gilles, Zurfluh


    This paper describes an object-oriented model for designing complex and time-variant data warehouse data. The main contribution is the warehouse class concept, which extends the class concept by temporal and archive filters as well as a mapping function. Filters allow the keeping of relevant data changes whereas the mapping function defines the warehouse class schema from a global data source schema. The approach take into account static properties as well as dynamic properties. The behaviour extraction is based on the use-matrix concept.

  8. Applied mathematics

    CERN Document Server

    Logan, J David


    Praise for the Third Edition"Future mathematicians, scientists, and engineers should find the book to be an excellent introductory text for coursework or self-study as well as worth its shelf space for reference." -MAA Reviews Applied Mathematics, Fourth Edition is a thoroughly updated and revised edition on the applications of modeling and analyzing natural, social, and technological processes. The book covers a wide range of key topics in mathematical methods and modeling and highlights the connections between mathematics and the applied and nat

  9. Modelisation et commande des redresseurs triphases fonctionnant a haut rendement et a faible taux de distorsion harmonique: Application au redresseur triphase de vienne (United States)

    Belhadj Youssef, Nesrine

    Les problemes de la qualite de l'onde electrique constituent l'une des preoccupations majeures des fournisseurs de l'energie et des organismes specialises en qualite d'energie. Ce sujet a gagne davantage d'ampleur avec l'utilisation ascendante des convertisseurs de l'energie electrique dans la majorite des applications industrielles et domestiques. Dans le cadre de cette these, on s'interesse plus particulierement au type des convertisseurs alternatif/continu, dont le fonctionnement adequat implique la parfaite regulation du bus DC de tension, l'attenuation des harmoniques de courants, la compensation de l'energie reactive et la maximisation du rendement energetique. Ces differents criteres doivent etre maintenus pour diverses conditions de fonctionnement, c'est-a-dire independamment des variations parametriques auxquelles le systeme peut etre sujet. Il s'avere donc indispensable d'adopter des techniques de commande efficaces, ce qui passe par une modelisation correcte du convertisseur. L'optimisation du nombre de capteurs dans le circuit est egalement un facteur cle a prendre en consideration.

  10. Time dependent modelisation of TeV blazars by a stratified jet model

    CERN Document Server

    Boutelier, Timothé; Petrucci, Pierre-Olivier


    We present a new time-dependent inhomogeneous jet model of non-thermal blazar emission. Ultra-relativistic leptons are injected at the base of a jet and propagate along it. We assume continuous reacceleration and cooling, producing a relativistic quasi-maxwellian (or "pile-up") particle energy distribution. The synchrotron and Synchrotron-Self Compton jet emissivity are computed at each altitude. Klein-Nishina effects as well as intrinsic gamma-gamma absorption are included in the computation. Due to the pair production optical depth, considerable particle density enhancement can occur, particularly during flaring states.Time-dependent jet emission can be computed by varying the particle injection, but due to the sensitivity of pair production process, only small variations of the injected density are required during the flares. The stratification of the jet emission, together with a pile-up distribution, allows significantly lower bulk Lorentz factors, compared to one-zone models. Applying this model to the ...

  11. Applied Enzymology. (United States)

    Manoharan, Asha; Dreisbach, Joseph H.


    Describes some examples of chemical and industrial applications of enzymes. Includes a background, a discussion of structure and reactivity, enzymes as therapeutic agents, enzyme replacement, enzymes used in diagnosis, industrial applications of enzymes, and immobilizing enzymes. Concludes that applied enzymology is an important factor in…

  12. Modelling and control of an electric vehicle; Modelisation et controle d`un vehicule electrique

    Energy Technology Data Exchange (ETDEWEB)

    Kwartnik, J.


    The work described in this report provides to engineers or researchers a tool for electric vehicle simulation. The different components included in the system are described with in particular the choppers, the pedal accelerator and the vehicle dynamic represented by the different constraints applied to the vehicle (efforts of drag, of lift, of rolling and slope resistance). This study has been realized by considering nonlinear phenomenons such as the armature magnetic reaction or the resistance change due to temperature increasing. The complexity of the system leads to use several of control. The theory of linear systems made possible the synthesis of PID controllers after few hypothesis. An on line adaptation technique completed this synthesis by considering nonlinear effects. For the cruise control we have used a control based on fuzzy set theory. We showed through two examples, the cruise control and the motor control using a strategy which minimize the Joule effect looses, the interest and the possibilities of the model evolution. (author) 21 refs.

  13. Modelisation geometrique par NURBS pour le design aerodynamique des ailes d'avion (United States)

    Bentamy, Anas

    The constant evolution of the computer science gives rise to many research areas especially in computer aided design. This study is part, of the advancement of the numerical methods in engineering computer aided design, specifically in aerospace science. The geometric modeling based on NURBS has been applied successfully to generate a parametric wing surface for aerodynamic design while satisfying manufacturing constraints. The goal of providing a smooth geometry described with few parameters has been achieved. In that case, a wing design including ruled surfaces at the leading edge slat and at the flap, and, curved central surfaces with intrinsic geometric property coming from conic curves, necessitates 130 control points and 15 geometric design variables. The 3D character of the wing need to be analyzed by techniques of investigation of surfaces in order to judge conveniently the visual aspect and detect any sign inversion in both directions of parametrization u and nu. Color mapping of the Gaussian curvature appears to be a very effective tools in visualization. The automation of the construction has been attained using an heuristic optimization algorithm, simulated annealing. The relative high speed of convergence to the solutions confirms its practical interest in engineering problems nowadays. The robustness of the geometric model has been tested successfully with an academic inverse design problem. The results obtained allow to foresee multiple possible applications from an extension to a complete geometric description of an airplane to the interaction with others disciplines belonging to a preliminary aeronautical design process.

  14. Applied dynamics

    CERN Document Server

    Schiehlen, Werner


    Applied Dynamics is an important branch of engineering mechanics widely applied to mechanical and automotive engineering, aerospace and biomechanics as well as control engineering and mechatronics. The computational methods presented are based on common fundamentals. For this purpose analytical mechanics turns out to be very useful where D’Alembert’s principle in the Lagrangian formulation proves to be most efficient. The method of multibody systems, finite element systems and continuous systems are treated consistently. Thus, students get a much better understanding of dynamical phenomena, and engineers in design and development departments using computer codes may check the results more easily by choosing models of different complexity for vibration and stress analysis.

  15. Participatory tools working with crops, varieties and seeds. A guide for professionals applying participatory approaches in agrobiodiversity management, crop improvement and seed sector development

    NARCIS (Netherlands)

    Boef, de W.S.; Thijssen, M.H.


    Outline to the guide Within our training programmes on local management of agrobiodiversity, participatory crop improvement and the support of local seed supply participatory tools get ample attention. Tools are dealt with theoretically, are practised in class situations, but are also applied in fie

  16. Consideraciones sobre la investigacion hermeneutica en la educacion en lenguas y culturas extranjeras (Aspects of Applying a Hermeneutic Approach to Foreign Language and Culture Education). (United States)

    Zoreda, Margaret Lee

    Drawing on writings by recent post-modernist thinkers and semioticians, this paper focuses on a combination of hermeneutic and semiotic viewpoints and applies them to defining the nature of interpretation in an educational setting (e.g., text interpretation), the interpreter, and the essence of the act of comprehension and interpretation. The main…

  17. Modelling aerosol transfer in a ventilated room; Modelisation du transfert des aerosols dans un local ventile

    Energy Technology Data Exchange (ETDEWEB)

    Nerisson, Ph.


    When particulate radioactive contamination is likely to become airborne in a ventilated room, assessment of aerosol concentration in every point of this room is important, in order to ensure protection of operators and supervision of workspaces. Thus, a model of aerosol transport and deposition has been developed as part of a project started with IRSN, EDF and IMFT. A simplified Eulerian model, called 'diffusion-inertia model' is used for particle transport. It contains a single transport equation of aerosol concentration. The specific study of deposition on walls has permitted to develop a boundary condition approach, which determines precisely the particle flux towards the wall in the boundary layer, for any deposition regime and surface orientation.The final transport and deposition models retained have been implemented in a CFD code called Code-Saturne. These models have been validated according to literature data in simple geometries and tracing experiments in ventilated rooms, which have been carried out in 30 m{sup 3} and 1500 m{sup 3} laboratory rooms. (author)

  18. European oil product supply modelling; Modelisation de l`offre de produits petroliers en Europe

    Energy Technology Data Exchange (ETDEWEB)

    Saint-Antonin, V


    Over the last few years, trends in European oil product consumption (in terms of level as structure and quality) has important implications of the refining industry. In this context, the purpose of this thesis consists in building a mathematical programming model applied to the European refineries in order to determine oil product supply prices, European refining industry investments and oil product exchanges of the European Union. The first part presents the reason for our choice for a long-term aggregate multi-refineries linear programming model, based on European refineries characteristics and the objectives of our model. Its dual properties are studied in detail and we focus particularly on the European exchange modelling. In the second part, an analysis of the European refining trends leads us to identify parameters and variables of the model that are essential to the aggregate representation of the European oil product supply. The third part is devoted to the use of this model, regarding two scenarios of increasingly stringent specifications for gasoline and diesel oil. Our interest for these products is due to their important share of the European oil product consumption and the not insignificant responsibility of the transport sector for atmospheric pollution. Finally, in order to have the use of an overall picture of the European refining industry, we build a regression model summarizing, though a few equations, the main relations between the major endogenous and exogenous variables o the LP model. Based on pseudo-data, this kind of model provides a simple and robust representation of the oil product supply. But a more specialized analysis of the refining industry operations, turning on a technical assessment of processing units, is reliant on the use of an optimization model such as the model we have built. (author) 102 refs.

  19. Physical modelling of interactions between interfaces and turbulence; Modelisation physique des interactions entre interfaces et turbulence

    Energy Technology Data Exchange (ETDEWEB)

    Toutant, A


    The complex interactions between interfaces and turbulence strongly impact the flow properties. Unfortunately, Direct Numerical Simulations (DNS) have to entail a number of degrees of freedom proportional to the third power of the Reynolds number to correctly describe the flow behaviour. This extremely hard constraint makes it impossible to use DNS for industrial applications. Our strategy consists in using and improving DNS method in order to develop the Interfaces and Sub-grid Scales concept. ISS is a two-phase equivalent to the single-phase Large Eddy Simulation (LES) concept. The challenge of ISS is to integrate the two-way coupling phenomenon into sub-grid models. Applying a space filter, we have exhibited correlations or sub-grid terms that require closures. We have shown that, in two-phase flows, the presence of a discontinuity leads to specific sub-grid terms. Comparing the maximum of the norm of the sub-grid terms with the maximum of the norm of the advection tensor, we have found that sub-grid terms related to interfacial forces and viscous effect are negligible. Consequently, in the momentum balance, only the sub-grid terms related to inertia have to be closed. Thanks to a priori tests performed on several DNS data, we demonstrate that the scale similarity hypothesis, reinterpreted near discontinuity, provides sub-grid models that take into account the two-way coupling phenomenon. These models correspond to the first step of our work. Indeed, in this step, interfaces are smooth and, interactions between interfaces and turbulence occur in a transition zone where each physical variable varies sharply but continuously. The next challenge has been to determine the jump conditions across the sharp equivalent interface corresponding to the sub-grid models of the transition zone. We have used the matched asymptotic expansion method to obtain the jump conditions. The first tests on the velocity of the sharp equivalent interface are very promising (author)

  20. Jesus, psychological type and conflict: A study in biblical hermeneutics applying the reader perspective and SIFT approach to Mark 11:11–21

    Directory of Open Access Journals (Sweden)

    Leslie J. Francis


    Full Text Available The Marcan account of Jesus riding into Jerusalem on a donkey, cursing the fig tree and overturning the tables of the money changers in the temple provides a classic scriptural reference point for a Christian discussion of conflict. Drawing on psychological type theory and on the reader perspective proposed by the SIFT (sensing, intuition, feeling and thinking approach to biblical hermeneutics and liturgical preaching, this study tests the theory that different psychological types will interpret this classic passage differently. Data collected in two residential programmes concerned with Christianity and conflict from type-aware participants confirmed characteristic differences between the approaches of sensing types and intuitive types and between the approaches of thinking types and feeling types.

  1. Frequency and damping ratio assessment of high-rise buildings using an Automatic Model-Based Approach applied to real-world ambient vibration recordings (United States)

    Nasser, Fatima; Li, Zhongyang; Gueguen, Philippe; Martin, Nadine


    This paper deals with the application of the Automatic Model-Based Approach (AMBA) over actual buildings subjected to real-world ambient vibrations. In a previous paper, AMBA was developed with the aim of automating the estimation process of the modal parameters and minimizing the estimation error, especially that of the damping ratio. It is applicable over a single-channel record, has no parameters to be set, and no manual initialization phase. The results presented in this paper should be regarded as further documentation of the approach over real-world ambient vibration signals.

  2. Modelisation of the contribution of sediments in the treatment process case of aerated lagoons. (United States)

    Jupsin, H; Vasel, J L


    In aerated lagoons and even more in stabilization ponds the specific power (W/m3) is not high enough to maintain all the suspended solids in suspension. Some part of the suspended solids (including biomass) settles directly into the reactor and not in the final settling pond. The gradual accumulation of those sediments on the pond bottom affects performance by reducing the pond volume and shortening the Hydraulic Residence Time. However, the role played by these deposits is not restricted to such a physical effect. Far from being inert sediments they are also an important oxygen sink that must be taken into account when designing aerator power and oxygen supply, for example. On the other hand, under aerobic conditions, the upper layer of sediments may contribute to the treatment as a biofilm compartment in the reactor. In aerated lagoon systems another process contributes to the interaction of deposits and the liquid phase: the operating (often sequencing) of aerators may induce a drastic resuspension of deposits. In a 3,000 m3 aerated lagoon we evaluated that 3 tons of deposits were resuspended when aerators were started. Due to those processes we consider that a mathematical model of an aerated lagoon or of a stabilization pond has to take into account the contribution (positive and negative aspects) of deposits in the process. In this paper we propose a model for sediments including production but also biological processes. Simulations of the aerated lagoon with or without the "sediment compartment" demonstrate the effect and the importance of this compartment on the process. Of course a similar approach could be used for facultative or even maturation ponds. The next step would be to include anaerobic activities in the bottom layer.

  3. Our System IDCBR-MAS: from the Modelisation by AUML to the Implementation under JADE Platform

    Directory of Open Access Journals (Sweden)

    Abdelhamid Zouhair


    Full Text Available This paper presents our work in the field of Intelligent Tutoring System (ITS, in fact there is still the problem of knowing how to ensure an individualized and continuous learners follow-up during learning process, indeed among the numerous methods proposed, very few systems concentrate on a real time learners follow-up. Our work in this field develops the design and implementation of a Multi-Agents System Based on Dynamic Case Based Reasoning which can initiate learning and provide an individualized follow-up of learner. This approach involves 1 the use of Dynamic Case Based Reasoning to retrieve the past experiences that are similar to the learner’s traces (traces in progress, and 2 the use of Multi-Agents System. Our Work focuses on the use of the learner traces. When interacting with the platform, every learner leaves his/her traces on the machine. The traces are stored in database, this operation enriches collective past experiences. The traces left by the learner during the learning session evolve dynamically over time; the case-based reasoning must take into account this evolution in an incremental way. In other words, we do not consider each evolution of the traces as a new target, so the use of classical cycle Case Based reasoning in this case is insufficient and inadequate. In order to solve this problem, we propose a dynamic retrieving method based on a complementary similarity measure, named Inverse Longest Common Sub-Sequence (ILCSS. Through monitoring, comparing and analyzing these traces, the system keeps a constant intelligent watch on the platform, and therefore it detects the difficulties hindering progress, and it avoids possible dropping out. The system can support any learning subject. To help and guide the learner, the system is equipped with combined virtual and human tutors.

  4. A Study With Special Emphasis On Applying Motivational Interviewing As a Clinical Approach to Change Addictive Behavior of Drug Abusers in Iran

    Directory of Open Access Journals (Sweden)

    Majid Ghorbani


    The goals of present article are three – fold: In the first step, it introduces a brief form of motivational Interviewing for addictive behaviors. Its primary basis is the idea that most substance abusers seek medical treatment without being ready to change addictive behaviors. As a result, attempts the addicts to change often lead to their resistance. Therefore, the use of motivational interviewing (MI in which clients are directed towards realizing their own reasons and arguments for changing their behavior, seems to be most oppropriate to motivate and prepare them for change. In the second step, the article tries to discuss advantages of motivational interviewing approach to often opproaches (e.g, skills training approach, Indirect approach and confrontational – denial approach and suggests that (MI is the most appropriate strategy for the substance abusers, according to their degree of readiness for change. Finally in the third step, the article attempts to indicate the current dominant strategies of addiction treatment in Iran and concludes that due to dominance and commonality of medicine – based treatment strategies of addictive behaviors, (MI could be introduced as an alternative and appropriate treatment strategy for drug addicts in Iran.

  5. Toward an understanding of biogenic-silica dissolution in seawater – An initial rate approach applied between 40 and 90°C

    NARCIS (Netherlands)

    Greenwood, J.E.; Truesdale, V.W.; Rendell, A.R.


    The kinetics of phytoplankton frustule dissolution has generally been studied as the appearance of silicic acid in a batch reactor. Unfortunately, this approach, though often illuminating, has not so far been successful because of the difficulty of parameterising the full reaction curve. This curren

  6. The hydro-mechanical modeling of the fractured media; Modelisation hydromecanique des milieux fractures

    Energy Technology Data Exchange (ETDEWEB)

    Kadiri, I


    The hydro-mechanical modeling of the fractured media is quite complex. Simplifications are necessary for the modeling of such media, but, not always justified, Only permeable fractures are often considered. The rest of the network is approximated by an equivalent continuous medium. Even if we suppose that this approach is validated, the hydraulic and mechanical properties of the fractures and of the continuous medium are seldom known. Calibrations are necessary for the determination of these properties. Until now, one does not know very well the nature of measurements which must be carried out in order to carry on a modeling in discontinuous medium, nor elements of enough robust validation for this kind of modeling. For a better understanding of the hydro-mechanical phenomena in fractured media, two different sites have been selected for the work. The first is the site of Grimsel in Switzerland in which an underground laboratory is located at approximately 400 m of depth. The FEBEX experiment aims at the in-situ study of the consecutive phenomena due to the installation of a heat source representative of radioactive waste in the last 17 meters of the FEBEX tunnel in the laboratory of Grimsel. Only, the modeling of the hydro-mechanical of the excavation was model. The modeling of the Febex enabled us to establish a methodology of calibration of the hydraulic properties in the discontinuous media. However, this kind of study on such complex sites does not make possible to answer all the questions which arise on the hydro-mechanical behavior of the fractured media. We thus carried out modeling on an other site, smaller than the fist one and more accessible. The experimental site of Coaraze, in the Maritime Alps, is mainly constituted of limestone and fractures. Then the variation of water pressure along fractures is governed by the opening/closure sequence of a water gate. Normal displacement as well as the pore pressure along these fractures are recorded, and then

  7. In silico optimization of pharmacokinetic properties and receptor binding affinity simultaneously: a 'parallel progression approach to drug design' applied to β-blockers. (United States)

    Advani, Poonam; Joseph, Blessy; Ambre, Premlata; Pissurlenkar, Raghuvir; Khedkar, Vijay; Iyer, Krishna; Gabhe, Satish; Iyer, Radhakrishnan P; Coutinho, Evans


    The present work exploits the potential of in silico approaches for minimizing attrition of leads in the later stages of drug development. We propose a theoretical approach, wherein 'parallel' information is generated to simultaneously optimize the pharmacokinetics (PK) and pharmacodynamics (PD) of lead candidates. β-blockers, though in use for many years, have suboptimal PKs; hence are an ideal test series for the 'parallel progression approach'. This approach utilizes molecular modeling tools viz. hologram quantitative structure activity relationships, homology modeling, docking, predictive metabolism, and toxicity models. Validated models have been developed for PK parameters such as volume of distribution (log Vd) and clearance (log Cl), which together influence the half-life (t1/2) of a drug. Simultaneously, models for PD in terms of inhibition constant pKi have been developed. Thus, PK and PD properties of β-blockers were concurrently analyzed and after iterative cycling, modifications were proposed that lead to compounds with optimized PK and PD. We report some of the resultant re-engineered β-blockers with improved half-lives and pKi values comparable with marketed β-blockers. These were further analyzed by the docking studies to evaluate their binding poses. Finally, metabolic and toxicological assessment of these molecules was done through in silico methods. The strategy proposed herein has potential universal applicability, and can be used in any drug discovery scenario; provided that the data used is consistent in terms of experimental conditions, endpoints, and methods employed. Thus the 'parallel progression approach' helps to simultaneously fine-tune various properties of the drug and would be an invaluable tool during the drug development process.

  8. Modelisation et simulation de pyrolyse de pneus usages dans des reacteurs de laboratoire et industriel (United States)

    Lanteigne, Jean-Remi

    The present thesis covers an applied study on tire pyrolysis. The main objective is to develop tools to allow predicting the production and the quality of oil from tire pyrolysis. The first research objective consisted in modelling the kinetics of tires pyrolysis in a reactor, namely an industrial rotary drum operating in batch mode. A literature review performed later demonstrated that almost all kinetics models developed to represent tire pyrolysis could not represent the actual industrial process with enough accuracy. Among the families of kinetics models for pyrolysis, three have been identified: models with one single global reaction, models with multiple combined parallel reactions, and models with multiple parallel and series reactions. It was observed that these models show limitations. In the models with one single global reaction and with multiple parallels reactions, the production of each individual pyrolytic product cannot be predicted, but only for combined volatiles. Morevoer, the mass term in the kinetics refers to the final char weight (Winfinity) that varies with pyrolysis conditions, which yields less robust models. Also, despite the fact that models with multiple parallels and series reactions can predict the rate of production for each pyrolysis product, the selectivities are determined for operating temperatures instead of real mass temperatures, giving models for which parameters tuning is not adequate when used at the industrial scale. A new kinetics model has been developed, allowing predicting the rate of production of noncondensable gas, oil, and char from tire pyrolysis. The novelty of this model is the consideration of intrinsic selectivities for each product as a function of temperature. This hypothesis has been assumed valid considering that in the industrial pyrolysis process, pyrolysis kinetics is limiting. The developed model considers individual kinetics for each of the three pyrolytic products proportional to the global

  9. Modelisation de materiaux composites adaptatifs munis d'actionneurs en alliage a memoire de forme (United States)

    Simoneau, Charles

    Technological development of structures having the capabilities to adapt themselves to different operating conditions is increasing in many areas of research such as aerospace. In fact, numerous works are now oriented toward the design of adaptive aircraft wings where the goal is to enhance the aerodynamic properties of the wing. Following this approach, the work realised in the framework of this master thesis presents the steps leading to the creation of a numerical model that can be used to predict the behavior of an adaptive panel, and therefore, eventually of an adaptive aircraft wing. Foremost, the adaptive panel of this project has been designed from a carbon-epoxy composite, acting as host structure, where shape memory alloy (SMA) wires, acting as actuators, have been inserted in it. SMA actuators have also been embedded asymmetrically along the direction of the panel thickness in order to generate a bending moment when the SMA wires are activated. To achieve the modeling of such structure it has been firstly shown that a numerical model composed of only solid finite elements could be used to represent the panel. However, a second numerical model composed of shell, beam and link finite elements showed that identical results can be obtained with much less nodes (the first model was composed of more than 300 000 nodes compared with 1 000 nodes for the second). The combination of shell-beam-link elements has then been chosen. Secondly, a constitutive relation had to be used for modeling the particular behavior of SMA. For the present work, a uniaxial version of the Likhachev's model is used. Due to its fairly straightforward mathematical formulation, this material law is able to model the main functional properties of SMA including the two-way shape memory effect (TWSME) at zero stress obtained after a thermomechanical education treatment. The last step was to compare the results of the numerical simulations with those obtained with a prototype where 19

  10. 各种骨瓣眶颧入路的应用解剖进展%Applied anatomy progress on various pieces of orbitozygomatic approach

    Institute of Scientific and Technical Information of China (English)

    冯学泉; 佟小光


    目的:总结各种骨瓣眶颧入路的应用解剖进展。方法在万方、CNKI及Pubmed等数据库查阅国内外各种不同骨瓣成形方式的眶颧手术入路的相关文献资料,并进行汇总分析。结果眶颧入路可分为单骨瓣眶颧入路、双骨瓣眶颧入路和三骨瓣眶颧入路,目前常用的为三骨瓣眶颧入路,该方法操作简便,在保障暴露效果的前提下,增加了术式的灵活性。结论眶颧入路的演变过程充分体现出随着相关应用解剖研究的进展,颅底外科从过分追求颅骨、病变切除的传统理念到兼顾患者安全、美观与生活质量的微创理念的变化。%Objective To summarize the research progress on orbitozygomatic approach of different bone pieces. Methods To consult and analyze recent studies of orbitozygomatic approach from Wanfang, CNKI, Pubmed and other databases. Results Orbitozygomatic approach can be divided into one-piece, two-piece and three-piece orbitozygomatic approach, and three-piece orbitozygomatic approach has been widely used at present, which is easy to operate, under the premise of providing effective exposure, and increases the surgical flexibility. Conclusions The evolution of orbitozygomatic approach fully reflects the progress of related applications with the anatomy of the skull base surgery, from the traditional concept of pursuit excessive removal of the skull and lesion to balance security, changes in appearance and quality of life in patients with minimally invasive concept.

  11. Thermodynamical modeling of nuclear glasses: coexistence of amorphous phases; Modelisation thermodynamique des verres nucleaires: coexistence entre phases amorphes

    Energy Technology Data Exchange (ETDEWEB)

    Adjanor, G


    Investigating the stability of borosilicate glasses used in the nuclear industry with respect to phase separation requires to estimate the Gibbs free energies of the various phases appearing in the material. In simulation, using current computational resources, a direct state-sampling of a glassy system with respect to its ensemble statistics is not ergodic and the estimated ensemble averages are not reliable. Our approach consists in generating, at a given cooling rate, a series of quenches, or paths connecting states of the liquid to states of the glass, and then in taking into account the probability to generate the paths leading to the different glassy states in ensembles averages. In this way, we introduce a path ensemble formalism and calculate a Landau free energy associated to a glassy meta-basin. This method was validated by accurately mapping the free energy landscape of a 38-atom glassy cluster. We then applied this approach to the calculation of the Gibbs free energies of binary amorphous Lennard-Jones alloys, and checked the correlation between the observed tendencies to order or to phase separate and the computed Gibbs free energies. We finally computed the driving force to phase separation in a simplified three-oxide nuclear glass modeled by a Born-Mayer-Huggins potential that includes a three-body term, and we compared the estimated quantities to the available experimental data. (author)

  12. Applied Statistics with SPSS (United States)

    Huizingh, Eelko K. R. E.


    Accessibly written and easy to use, "Applied Statistics Using SPSS" is an all-in-one self-study guide to SPSS and do-it-yourself guide to statistics. What is unique about Eelko Huizingh's approach is that this book is based around the needs of undergraduate students embarking on their own research project, and its self-help style is designed to…

  13. Development of the Applied Baccalaureate (United States)

    Townsend, Barbara K.; Bragg, Debra D.; Ruud, Collin M.


    Increasing demands for economic competitiveness and educational effectiveness have led states and institutions to implement new approaches to facilitating baccalaureate completion. This study examined one of these approaches, the applied baccalaureate degree, which is designed to incorporate applied associate course work and degrees once…

  14. An adaptive Lagrangian boundary element approach for three-dimensional transient free-surface Stokes flow as applied to extrusion, thermoforming, and rheometry (United States)

    Khayat, Roger E.; Genouvrier, Delphine


    An adaptive (Lagrangian) boundary element approach is proposed for the general three-dimensional simulation of confined free-surface Stokes flow. The method is stable as it includes remeshing capabilities of the deforming free surface and thus can handle large deformations. A simple algorithm is developed for mesh refinement of the deforming free-surface mesh. Smooth transition between large and small elements is achieved without significant degradation of the aspect ratio of the elements in the mesh. Several flow problems are presented to illustrate the utility of the approach, particularly as encountered in polymer processing and rheology. These problems illustrate the transient nature of the flow during the processes of extrusion and thermoforming, the elongation of a fluid sample in an extensional rheometer, and the coating of a sphere. Surface tension effects are also explored. Copyright

  15. Comparative review of three cost-effectiveness models for rotavirus vaccines in national immunization programs; a generic approach applied to various regions in the world

    Directory of Open Access Journals (Sweden)

    Tu Hong-Anh


    Full Text Available Abstract Background This study aims to critically review available cost-effectiveness models for rotavirus vaccination, compare their designs using a standardized approach and compare similarities and differences in cost-effectiveness outcomes using a uniform set of input parameters. Methods We identified various models used to estimate the cost-effectiveness of rotavirus vaccination. From these, results using a standardized dataset for four regions in the world could be obtained for three specific applications. Results Despite differences in the approaches and individual constituting elements including costs, QALYs Quality Adjusted Life Years and deaths, cost-effectiveness results of the models were quite similar. Differences between the models on the individual components of cost-effectiveness could be related to some specific features of the respective models. Sensitivity analysis revealed that cost-effectiveness of rotavirus vaccination is highly sensitive to vaccine prices, rotavirus-associated mortality and discount rates, in particular that for QALYs. Conclusions The comparative approach followed here is helpful in understanding the various models selected and will thus benefit (low-income countries in designing their own cost-effectiveness analyses using new or adapted existing models. Potential users of the models in low and middle income countries need to consider results from existing studies and reviews. There will be a need for contextualization including the use of country specific data inputs. However, given that the underlying biological and epidemiological mechanisms do not change between countries, users are likely to be able to adapt existing model designs rather than developing completely new approaches. Also, the communication established between the individual researchers involved in the three models is helpful in the further development of these individual models. Therefore, we recommend that this kind of comparative study

  16. Abordagem adaptativa aplicada ao planejamento agregado da produção sob incertezas Adaptive approach applied to aggregate production planning under uncertainties

    Directory of Open Access Journals (Sweden)

    Oscar Salviano Silva Filho


    Full Text Available Um problema de planejamento agregado da produção, com incertezas sobre a flutuação da demanda, é formulado através de um modelo de otimização estocástica, com critério quadrático e restrições lineares. Dificuldades para encontrar uma solução ótima global para o problema levam à proposição de uma abordagem adaptativa de fácil implementação computacional que é baseada na formulação de um problema determinístico equivalente e que tem sua solução periodicamente revisada por meio de um procedimento clássico da literatura. Um exemplo, em que o sistema de balanço de estoque está sujeito à forte e fraca variabilidade da demanda real, é empregado para analisar o comportamento da abordagem proposta. Por fim, os resultados obtidos são comparados com outra abordagem subótima, cuja principal característica é não permitir revisões periódicas.A problem of aggregate production planning, with uncertainty about the fluctuation in demand, is formulated by a stochastic optimization model, with quadratic criterion and linear constraints. Difficulties in finding a global optimum solution to the problem lead to the proposal of an adaptive approach which is easy to implement computationally and which is based on the formulation of a deterministic equivalent problem, the solution for which is periodically reviewed through a classical procedure of literature. An example, where the inventory balance system is subject to weak and strong variability in actual demand, is employed to analyze the behavior of the proposed approach. Finally, the results provided by the proposed approach are compared with another suboptimal approach, the main characteristic of which is not allowing periodic reviews.

  17. A comparative study of first and all-author co-citation counting, and two different matrix generation approaches applied for author co-citation analyses

    DEFF Research Database (Denmark)

    Schneider, Jesper Wiborg; Larsen, Birger; Ingwersen, Peter


    XML documents extracted from the IEEE collection. These data allow the construction of ad-hoc citation indexes, which enables us to carry out the hitherto largest all-author co-citation study. Four ACA are made, combining the different units of analyses with the different matrix generation approaches...... into groupings. Finally, the study also demonstrates the importance of sparse matrices and their potential problems in connection with factor analysis. Conclusion: We can confirm that inclusive all-ACA produce more coherent groupings of authors, whereas the present study cannot clearly confirm previous findings...

  18. Applied combustion

    Energy Technology Data Exchange (ETDEWEB)



    From the title, the reader is led to expect a broad practical treatise on combustion and combustion devices. Remarkably, for a book of modest dimension, the author is able to deliver. The text is organized into 12 Chapters, broadly treating three major areas: combustion fundamentals -- introduction (Ch. 1), thermodynamics (Ch. 2), fluid mechanics (Ch. 7), and kinetics (Ch. 8); fuels -- coal, municipal solid waste, and other solid fuels (Ch. 4), liquid (Ch. 5) and gaseous (Ch. 6) fuels; and combustion devices -- fuel cells (Ch. 3), boilers (Ch. 4), Otto (Ch. 10), diesel (Ch. 11), and Wankel (Ch. 10) engines and gas turbines (Ch. 12). Although each topic could warrant a complete text on its own, the author addresses each of these major themes with reasonable thoroughness. Also, the book is well documented with a bibliography, references, a good index, and many helpful tables and appendices. In short, Applied Combustion does admirably fulfill the author`s goal for a wide engineering science introduction to the general subject of combustion.

  19. Integrated risk assessment for WFD ecological status classification applied to Llobregat river basin (Spain). Part I-Fuzzy approach to aggregate biological indicators. (United States)

    Gottardo, S; Semenzin, E; Giove, S; Zabeo, A; Critto, A; de Zwart, D; Ginebreda, A; Marcomini, A


    Water Framework Directive (WFD) requirements and recommendations for Ecological Status (ES) classification of surface water bodies do not address all issues that Member States have to face in the implementation process, such as selection of appropriate stressor-specific environmental indicators, definition of class boundaries, aggregation of heterogeneous data and information and uncertainty evaluation. In this context the "One-Out, All-Out" (OOAO) principle is the suggested approach to lead the entire classification procedure and ensure conservative results. In order to support water managers in achieving a more comprehensive and realistic evaluation of ES, an Integrated Risk Assessment (IRA) methodology was developed. It is based on the Weight of Evidence approach and implements a Fuzzy Inference System in order to hierarchically aggregate a set of environmental indicators, which are grouped into five Lines of Evidence (i.e. Biology, Chemistry, Ecotoxicology, Physico-chemistry and Hydromorphology). The whole IRA methodology has been implemented as an individual module into a freeware GIS (Geographic Information System)-based Decision Support System (DSS), named MODELKEY DSS. The paper focuses on the conceptual and mathematical procedure underlying the evaluation of the most complex Line of Evidence, i.e. Biology, which identifies the biological communities that are potentially at risk and the stressors that are most likely responsible for the observed alterations. The results obtained from testing the procedure through application of the MODELKEY DSS to the Llobregat case study are reported and discussed.

  20. Fuzzy sets, rough sets, and modeling evidence: Theory and Application. A Dempster-Shafer based approach to compromise decision making with multiattributes applied to product selection (United States)

    Dekorvin, Andre


    The Dempster-Shafer theory of evidence is applied to a multiattribute decision making problem whereby the decision maker (DM) must compromise with available alternatives, none of which exactly satisfies his ideal. The decision mechanism is constrained by the uncertainty inherent in the determination of the relative importance of each attribute element and the classification of existing alternatives. The classification of alternatives is addressed through expert evaluation of the degree to which each element is contained in each available alternative. The relative importance of each attribute element is determined through pairwise comparisons of the elements by the decision maker and implementation of a ratio scale quantification method. Then the 'belief' and 'plausibility' that an alternative will satisfy the decision maker's ideal are calculated and combined to rank order the available alternatives. Application to the problem of selecting computer software is given.

  1. Collaborative Approaches to Increase the Utility of Spatial Data for the Wildfire Management Community Through NASA's Applied Remote Sensing Training Program (United States)

    McCullum, A. J. K.; Schmidt, C.; Blevins, B.; Weber, K.; Schnase, J. L.; Carroll, M.; Prados, A. I.


    The utility of spatial data products and tools to assess risk and effectively manage wildfires has increased, highlighting the need for communicating information about these new capabilities to decision makers, resource managers, and community leaders. NASA's Applied Remote Sensing Training (ARSET) program works directly with agencies and policy makers to develop in-person and online training courses that teach end users how to access, visualize, and apply NASA Earth Science data in their profession. The expansion of ARSET into wildfire applications began in 2015 with a webinar and subsequent in-person training hosted in collaboration with Idaho State University's (ISU) GIS Training and Research Center (TReC). These trainings featured presentations from the USDA Forest Service's Remote Sensing Training and Applications Center, the Land Processes DAAC, Northwest Nazarene University, NASA Goddard Space Flight Center, and ISU's GIS TReC. The webinar focused on providing land managers, non-governmental organizations, and international management agencies with an overview of 1) remote sensing platforms for wildfire applications, 2) products for pre- and post-fire planning and assessment, 3) the use of terrain data, 4) new techniques and technologies such as Unmanned Aircraft Systems and the Soil Moisture Active Passive Mission (SMAP), and 5) the RECOVER Decision Support System. This training highlighted online tools that engage the wildfire community through collaborative monitoring and assessment efforts. Webinar attendance included 278 participants from 178 organizations in 42 countries and 33 US states. The majority of respondents (93%) from a post-webinar survey indicated they displayed improvement in their understanding of specific remote-sensing data products appropriate for their work needs. With collaborative efforts between federal, state, and local agencies and academic institutions, increased use of NASA Earth Observations may lead to improved near real

  2. A novel approach for modeling malaria incidence using complex categorical household data: The minimum message length (MML method applied to Indonesian data

    Directory of Open Access Journals (Sweden)

    Gerhard Visser


    Full Text Available We investigated the application of a Minimum Message Length (MML modeling approach to identify the simplest model that would explain two target malaria incidence variables: incidence in the short term and on the average longer term, in two areas in Indonesia, based on a range of ecological variables including environmental and socio-economic ones. The approach is suitable for dealing with a variety of problems such as complexity and where there are missing values in the data. It can detect weak relations, is resistant to overfittingand can show the way in which many variables, working together, contribute to explaining malaria incidence. This last point is a major strength of the method as it allows many variables to be analysed. Data were obtained at household level by questionnaire for villages in West Timor and Central Java. Data were collected on 26 variables in nine categories: stratum (a village-level variable based on the API/AMI categories, ecology, occupation, preventative measures taken, health care facilities, the immediate environment, household characteristics, socio-economic status and perception of malaria cause. Several models were used and the simplest (best model, that is the one with the minimum message length was selected for each area. The results showed that consistent predictors of malaria included combinations of ecology (coastal, preventative (clean backyard and environment (mosquito breeding place, garden and rice cultivation. The models also showed that most of the other variables were not good predictors and this is discussed in the paper. We conclude that the method has potential for identifying simple predictors of malaria and that it could be used to focus malaria management on combinations of variables rather than relying on single ones that may not be consistently reliable.

  3. Dual-domain mass-transfer parameters from electrical hysteresis: theory and analytical approach applied to laboratory, synthetic streambed, and groundwater experiments (United States)

    Briggs, Martin; Day-Lewis, Frederick D.; Ong, John B.; Harvey, Judson W.; Lane, Jr., John W.


    Models of dual-domain mass transfer (DDMT) are used to explain anomalous aquifer transport behavior such as the slow release of contamination and solute tracer tailing. Traditional tracer experiments to characterize DDMT are performed at the flow path scale (meters), which inherently incorporates heterogeneous exchange processes; hence, estimated “effective” parameters are sensitive to experimental design (i.e., duration and injection velocity). Recently, electrical geophysical methods have been used to aid in the inference of DDMT parameters because, unlike traditional fluid sampling, electrical methods can directly sense less-mobile solute dynamics and can target specific points along subsurface flow paths. Here we propose an analytical framework for graphical parameter inference based on a simple petrophysical model explaining the hysteretic relation between measurements of bulk and fluid conductivity arising in the presence of DDMT at the local scale. Analysis is graphical and involves visual inspection of hysteresis patterns to (1) determine the size of paired mobile and less-mobile porosities and (2) identify the exchange rate coefficient through simple curve fitting. We demonstrate the approach using laboratory column experimental data, synthetic streambed experimental data, and field tracer-test data. Results from the analytical approach compare favorably with results from calibration of numerical models and also independent measurements of mobile and less-mobile porosity. We show that localized electrical hysteresis patterns resulting from diffusive exchange are independent of injection velocity, indicating that repeatable parameters can be extracted under varied experimental designs, and these parameters represent the true intrinsic properties of specific volumes of porous media of aquifers and hyporheic zones.

  4. Theophylline: a haemoperfusion modelisation. (United States)

    Laurent, D; Guenzet, J; Bourin, M


    A dynamic study of the kinetics of theophylline adsorption in aqueous medium by two adsorbent resins is proposed. The adsorption process involves Van der Walls pattern physical bonds. An in vitro haemoperfusion apparatus was schematized and data describing the adsorption-desorption process was obtained. A mathematical treatment led to the conclusion that first-order adsorption and desorption rates are involved, results which led to the consideration of a model of in vivo haemoperfusion in the case of first-order adsorption and desorption, with first-order corporeal elimination. The results indicate that one of the resins used, Amberlite XAD4, already known as a haemocompatible resin, is useful in eliminating theophylline.


    Directory of Open Access Journals (Sweden)

    Viorica Lefter


    Full Text Available Objectives. The objective of the present study is to relieve the necessity and the efficiency of the kinetic recovery of theoperated hip, and to increase the orthopedist’s trust in the kinetic act as a medical act executed in a responsible and understanding fashion by the qualified staff. Arthroplasty refers to the replacement of a joint deteriorated by a certain pathological process (degenerative arthritis, infection, or tumor with an artificial one, named endoprosthesis, a joint which must remain perfectly functional. The material and the method. The participants were 76 (63% mail patients and 45 (37% female patients, 44 (37% of which with ages between 40 and 60 years, 54 (45% between 60 and 70, and 21 (18% exceeded 70 years of ageInclusion criteria for the study werethe display of the following symptoms: chronic pain, acute pain andmobility reduction. Thus, 52 (42% patients featured acute pain, 42 (33% chronic pain and 35 (27% mobility disorders accompanied by walk disorders, that is, tilting pelvis 67 (55% and limping 54 (45% (Fig. 3, (Fig. 4 with hip prostheses of different types and at various intervals from the intervention. Subjects were clinically, functionally, radiologically and MRI investigated, preoperatively, postoperatively, after 3 months and after 1 year. A recovery program featuring educational, hygienic, diet, medication and physical-kinetic aspects was applied daily for a 14 to 15-day period, followed by kinesiotherapy and massage 2 to 3 times a week, by reevaluation and by a complete treatment at 3 months and at 1 year, respectively. Monitoring was made by the VAS scale for pain, Womac Lequesne for the functional status and Tinetii for the walk. Results. All patients have been evaluated initially, after 10 days and at the completion of the treatment, after 3 months and after 1 year. The recovery of hip arthroplasty must be carried out in time and maintained for the entire life.Conclusions.. Hips with applied endo

  6. Applied Ethics in Nowadays Society


    Tomita CIULEI


    This special issue is dedicated to Nowadays Applied Ethics in Society, and falls in the field of social sciences and humanities, being hosted both theoretical approaches and empirical research in various areas of applied ethics. Applied ethics analyzes of a series of morally concrete situations of social or professional practice in order to make / adopt decisions. In the field of applied ethics are integrated medical ethics, legal ethics, media ethics, professional ethics, environmental ethic...

  7. Relationships between vegetation indices and different burn and vegetation ratios: a multi-scale approach applied in a fire affected area (United States)

    Pleniou, M.; Koutsias, N.


    Vegetation indices have been widely used in remote sensing literature for burned land mapping and monitoring. In the present study we used satellite data (IKONOS, LANDSAT, ASTER, MODIS) of multiple spectral (visible, near, shortwave infrared) and spatial (1-500 meters) resolutions, acquired shortly after a very destructive fire occurred in the mountain of Parnitha in Attica, Greece the summer of 2007. The aim of our study is to examine and evaluate the performance of some vegetation indices for burned land mapping and also to characterize the relationships between vegetation indices and the percent of fire-scorched (burned) and non fire-scorched (vegetated) areas. The available satellite images were processed geometrically, radiometrically and atmospherically. The very high resolution IKONOS imagery was served as a base to estimate the percent of cover of burned areas, bare soil and vegetation by applying the maximum likelihood classification algorithm. The percent of cover for each type was then correlated to vegetation indices for all the satellite images, and regression models were fit to characterize those relationships. In total 57 versions of some classical vegetation indices were computed using LANDSAT, ASTER and MODIS data. Most of them were modified by replacing Red with SWIR channel, as the latter has been proved sensitive to burned area discrimination. IPVI and NDVI showed a better performance among the indices tested to estimate the percent of vegetation, while most of the modified versions of the indices showed highest performance to estimate the percent of burned areas.


    Institute of Scientific and Technical Information of China (English)

    张龙; 冯继; 刘银凤; 杨大伟; 李玉斌; 王永恒


    目的:对肌骨瓣眶颧入路进行解剖学研究,减少因传统眶颧入路造成的面神经颞支损伤及术后颞肌萎缩、颞窝塌陷的发生。方法:20侧尸头模拟肌骨瓣眶颧手术入路,观察术区面神经颞支和颞浅动脉额颞支的位置关系并测量二者之间的最短距离,测量MacCarty孔中心至额蝶缝的垂线距离和垂直点距额蝶缝末端的距离。结果:术区中面神经颞支均在颞浅动脉额颞支前下方走行,二者之间的最短距离为(4.80±2.40)mm, MacCarty孔位于额蝶缝上方,MacCarty孔中心距额蝶缝的垂直距离为(6.10±2.32)mm,垂直点至额蝶缝末端的距离为(22.42±4.12)mm。结论:颞浅动脉额颞支可做为筋膜间入路的解剖学标志;肌骨瓣血管神经保持完整降低了颞肌和骨萎缩的风险。%Objective:To reduce the incidence of temporal branch of facial nerve injury, temporal muscle atrophy and temporal fossa collapse induced by traditional orbitozygomatic approach.Methods:The muscle bone flap of orbitozygomatic approach was simulated in 20 sides cadaver heads.The relationship between temporal branch of facial nerve and frontotemporal branch of superficial temporal artery was observed and the shortest distance between them was measured. The vertical distance from the center of MacCarty keyhole to spheno-frontal suture, and the distance between the vertical point and the end of spheno-frontal suture were measured. Results:In surgical site, all the temporal branch of facial nerve ran anteroinferior to the frontotemporal branch of superficial temporal artery, and the shortest distance between them was (4.80±2.40)mm. The MacCarty keyhole was superior to the spheno-frontal suture, the vertical distance between the center of MacCarty keyhole and the spheno-frontal suture was (6.10±2.32)mm, the distance between the vertical point and the end of spheno-frontal suture was (22.42±4.12)mm.Conclusions:Frontotemporal branch of

  9. Introduction to applied thermodynamics

    CERN Document Server

    Helsdon, R M; Walker, G E


    Introduction to Applied Thermodynamics is an introductory text on applied thermodynamics and covers topics ranging from energy and temperature to reversibility and entropy, the first and second laws of thermodynamics, and the properties of ideal gases. Standard air cycles and the thermodynamic properties of pure substances are also discussed, together with gas compressors, combustion, and psychrometry. This volume is comprised of 16 chapters and begins with an overview of the concept of energy as well as the macroscopic and molecular approaches to thermodynamics. The following chapters focus o

  10. Trends in the theoretical and research methodological approaches applied in doctoral studies in information and knowledge management: an exploration of ten years of research in South Africa

    Directory of Open Access Journals (Sweden)

    M. A. Mearns


    Full Text Available The past ten years have seen the field of information and knowledge management develop and implement new and improved technologies. Because of the ease with which information is exchanged the contribution to information overload has increased exponentially and the need for information and knowledge management is more real than ever before. Research in itself is a science of knowledge creation that continuously evolves in line with newly developed theories and research methodologies. An investigation of the theories and research methodologies that doctoral theses, completed in South Africa, ascribed to over the past ten years were conducted. Search strings containing 'information management', 'knowledge management' and 'information and knowledge management' were searched within citation, abstract and subject fields. A sample of 30 theses from a possible 47 in the relevant population was identified. Qualitative and mixed methods research design was favoured, making use of case studies and surveys, but paying little attention to theoretical approaches or paradigms. The boundaries between disciplines are continuously re-defined, new disciplines evolve and traditional disciplines suffer under the pressures of changing problems of the world. The importance of research in the field of information and knowledge management being grounded in the most recent scientific thought is emphasized.

  11. Applying the WHO recommendations on health-sector response to violence against women to assess the Spanish health system. A mixed methods approach. (United States)

    Goicolea, Isabel; Vives-Cases, Carmen; Minvielle, Fauhn; Briones-Vozmediano, Erica; Ohman, Ann


    This methodological note describes the development and application of a mixed-methods protocol to assess the responsiveness of Spanish health systems to violence against women in Spain, based on the World Health Organization (WHO) recommendations. Five areas for exploration were identified based on the WHO recommendations: policy environment, protocols, training, accountability/monitoring, and prevention/promotion. Two data collection instruments were developed to assess the situation of 17 Spanish regional health systems (RHS) with respect to these areas: 1) a set of indicators to guide a systematic review of secondary sources, and 2) an interview guide to be used with 26 key informants at the regional and national levels. We found differences between RHSs in the five areas assessed. The progress of RHSs on the WHO recommendations was notable at the level of policies, moderate in terms of health service delivery, and very limited in terms of preventive actions. Using a mixed-methods approach was useful for triangulation and complementarity during instrument design, data collection and interpretation.

  12. Tracking the genealogy of CO{sub 2} emissions in the electricity sector: An intersectoral approach applied to the Spanish case

    Energy Technology Data Exchange (ETDEWEB)

    Tarancon Moran, Miguel Angel; Albinana, Fernando Callejas [Faculty of Law and Business, Universidad de Castilla - La Mancha, Ronda de Toledo s/n, 13071 Ciudad Real (Spain); Del Rio, Pablo [Facultad of Social Sciences and Law, Universidad de Castilla-La Mancha, C/Cobertizo de S. Pedro Martir s/n, Toledo 45071 (Spain)


    This paper analyses the factors leading to CO{sub 2} emissions in the Spanish electricity generation sector in order to propose effective mitigation policies aimed at tackling those emissions. Traditionally, two broad categories of those factors have been considered in the literature: those related to the supply of electricity (technological features of the sector) and those related to the level of economic activity (demand factors). This paper focuses on an additional element, which has usually been neglected, the structural factor, which refers to the set of intersectoral transactions (related to the technologies used in other productive sectors) which connect, in either a direct or an indirect way, the general economic activity with the supply of electricity and, thus, with the emissions of the electricity generation sector. This analysis allows us to identify the so-called 'sectors structurally responsible for emissions' (SSER), whose production functions involve transactions which connect the demand for goods and services with the emissions of the electricity generation sector. The methodology is based on an input-output approach and a sensitivity analysis. The paper shows that there are structural rigidities, deeply ingrained within the economic system, which lead to emissions from the electricity generation sector for which this sector cannot be held responsible. These rigidities limit the effectiveness of policies aimed at emissions mitigation in this sector. (author)

  13. Disclosing the Radio Loudness Distribution Dichotomy in Quasars: An Unbiased Monte Carlo Approach Applied to the SDSS-FIRST Quasar Sample

    CERN Document Server

    Balokovic, Mislav; Ivezic, Zeljko; Zamorani, Gianni; Schinnerer, Eva; Kelly, Brandon C


    We investigate the dichotomy in the radio loudness distribution of quasars by modelling their radio emission and various selection effects using a Monte Carlo approach. The existence of two physically distinct quasar populations, the radio-loud and radio-quiet quasars, is controversial and over the last decade a bimodal distribution of radio loudness of quasars has been both affirmed and disputed. We model the quasar radio luminosity distribution with simple unimodal and bimodal distribution functions. The resulting simulated samples are compared to a fiducial sample of 8,300 quasars drawn from the SDSS DR7 Quasar Catalog and combined with radio observations from the FIRST survey. Our results indicate that the SDSS-FIRST sample is best described by a radio loudness distribution which consists of two components, with 12+/-1 % of sources in the radio-loud component. On the other hand, the evidence for a local minimum in the loudness distribution (bimodality) is not strong and we find that previous claims for it...

  14. An Effective Hamiltonian Molecular Orbital-Valence Bond (MOVB) Approach for Chemical Reactions Applied to the Nucleophilic Substitution Reaction of Hydrosulfide Ion and Chloromethane. (United States)

    Song, Lingchun; Mo, Yirong; Gao, Jiali


    An effective Hamiltonian mixed molecular orbital and valence bond (EH-MOVB) method is described to obtain an accurate potential energy surface for chemical reactions. Building upon previous results on the construction of diabatic and adiabatic potential surfaces using ab initio MOVB theory, we introduce a diabatic-coupling scaling factor to uniformly scale the ab initio off-diagonal matrix element H(12) such that the computed energy of reaction from the EH-MOVB method is in agreement with the target value. The scaling factor is very close to unity, resulting in minimal alteration of the potential energy surface of the original MOVB model. Furthermore, the relative energy between the reactant and product diabatic states in the EH-MOVB method can be improved to match the experimental energy of reaction. A key ingredient in the EH-MOVB theory is that the off-diagonal matrix elements are functions of all degrees of freedom of the system and the overlap matrix is explicitly evaluated. The EH-MOVB method has been applied to the nucleophilic substitution reaction between hydrosulfide and chloromethane to illustrate the methodology and the results were matched to reproduce the results from ab initio valence bond self-consistent valence bond (VBSCF) calculations. The diabatic coupling (the off-diagonal matrix element in the generalized secular equation) has small variations along the minimum energy reaction path in the EH-MOVB model, whereas it shows a maximum value at the transition state and has nearly zero values in the regions of the ion-dipole complexes from VBSCF calculations. The difference in the diabatic coupling stabilization is attributed to the large overlap integral in the computationally efficient MOVB method.

  15. Modeling of columnar and equiaxed solidification of binary mixtures; Modelisation de la solidification colonnaire et equiaxe de melanges binaires

    Energy Technology Data Exchange (ETDEWEB)

    Roux, P


    This work deals with the modelling of dendritic solidification in binary mixtures. Large scale phenomena are represented by volume averaging of the local conservation equations. This method allows to rigorously derive the partial differential equations of averaged fields and the closure problems associated to the deviations. Such problems can be resolved numerically on periodic cells, representative of dendritic structures, in order to give a precise evaluation of macroscopic transfer coefficients (Drag coefficients, exchange coefficients, diffusion-dispersion tensors...). The method had already been applied for a model of columnar dendritic mushy zone and it is extended to the case of equiaxed dendritic solidification, where solid grains can move. The two-phase flow is modelled with an Eulerian-Eulerian approach and the novelty is to account for the dispersion of solid velocity through the kinetic agitation of the particles. A coupling of the two models is proposed thanks to an original adaptation of the columnar model, allowing for undercooling calculation: a solid-liquid interfacial area density is introduced and calculated. At last, direct numerical simulations of crystal growth are proposed with a diffuse interface method for a representation of local phenomena. (author)

  16. SIFT applied to CBIR

    Directory of Open Access Journals (Sweden)



    Full Text Available Content-Based Image Retrieval (CBIR is a challenging task. Common approaches use only low-level features. Notwithstanding, such CBIR solutions fail on capturing some local features representing the details and nuances of scenes. Many techniques in image processing and computer vision can capture these scene semantics. Among them, the Scale Invariant Features Transform~(SIFT has been widely used in a lot of applications. This approach relies on the choice of several parameters which directly impact its effectiveness when applied to retrieve images. In this paper, we discuss the results obtained in several experiments proposed to evaluate the application of the SIFT in CBIR tasks.

  17. Minimum critical thickness of dike for ore-bearing fluid injection: A new approach applied to the Shihu gold deposit, Hebei Province, North China

    Directory of Open Access Journals (Sweden)

    Dedong Li


    Full Text Available According to the metallogenic theory by transmagmatic fluid (TMF, one magmatic intrusion is a channel of ore-bearing fluids, but not their source. Therefore, it is possible to use TMF’s ability for injection into and for escaping from the magmatic intrusion to evaluate its ore-forming potential. As the ore-bearing fluids cannot effectively inject into the magmatic intrusion when the magma fully crystallized, the cooling time and rates viscosity varied can be used to estimate the minimum critical thickness of the intrusion. One dimensional heat transfer model is used to determine the cooling time for three representative dikes of different composition (granite porphyry, quartz diorite and diabase in the Shihu gold deposit. It also estimated the rates viscosity varied in these time interval. We took the thickness of dike at the intersection of the cooling time – thickness curve and the rates viscosity varied versus thickness curve as the minimum critical thickness. For the ore-bearing fluids effectively injecting into the magma, the minimum critical thicknesses for the three representative dikes are 33.45 m for granite porphyry, 8.22 m for quartz diorite and 1.02 m for diabase, indicating that ore-bearing dikes must be thicker than each value. These results are consistent with the occurrence of ore bodies, and thus they could be applied in practice. Based on the statistical relationship between the length and the width of dikes, these critical thicknesses are used to compute critical areas: 0.0003–0.0016 km2 for diabase, 0.014–0.068 km2 for quartz diorite and 0.011–0.034 km2 for granite porphyry. This implies that ore-bearing minor intrusions have varied areas corresponding to their composition. The numerical simulation has provided the theoretical threshold of exposed thickness and area of the ore-bearing intrusion. These values can be used to determine the ore-forming potentials of dikes.

  18. Applied anatomy of cervicothoracic spine anterior approach operation%颈胸段脊柱前方入路手术的应用解剖

    Institute of Scientific and Technical Information of China (English)



    Objective To explore the anatomical basis of cervicothoracic spine anterior operation.Methods A total of 39 bodies were selected.Through simulating the steps of exposure of the vertebral body by sternal and clavicular resection of cervicothoracic spine anterior surgery,rehional anatomy method was used to observe the C5-T3 vertebral body must be retracted and important structures of several protection in anterior approach from outside to inside,from the shallower to the deeper,then some important parameters were measured.Results The left brachiocephalic vein length was (67.8±11.2) mm,the vertical distance and brachiocephalic trunk node from the suprasternal notch was (52.6±21.3) mm,the horizontal distance of left venous angle and anterior midline was (43.3±8.8) mm.Vertical distance from the peak of pleura to 1/3 superior border of left clavicle was (8.1±2.2) mm,while,(13.1±2.9) mm on the right,the distance between left and right had significant difference (P < 0.05).The vertical distance and the horizontal dis tance from the peak of arch of thoracic duct to cricoid cartilage level and anterior midline were (19.2±4.3) mm and (34.1±2.1) mm.6 cases of right recurrent laryngeal nerve penetrated the visceral fascia located in G7-T1 intervertebral level,accounting for 15.38%,33 cases located in the upper T1 vertebral level,accounting for 84.62%.The crossing points of right recurrent laryngeal nerve and medial border of carotid artery located in T1 upper level were 9 cases,located in T1 lower level were 30 cases,accounting for 23.08% and 76.92% respectively.Conclusion Application of sternal and clavicular resection in the cervicothoracic spine anterior approach operation can make the C5-T3 fully exposed,only familiar with local anatomy can make the anterior operation normally developed,in order to decrease the incidence of iatrogenic complications.%目的 探讨颈胸段脊柱前路手术的解剖学依据.方法 选取39具尸体,通过模拟胸骨柄和

  19. Applied anatomy of presacral approach for axial lumbar interbody fusion%轴向腰椎椎间融合术入路的应用解剖

    Institute of Scientific and Technical Information of China (English)

    李向明; 张玉松; 侯致典; 吴涛; 丁自海


    Objective The aim of this study was to evaluate the safety of the presacral approach for axial lumbar interbody fusion.Methods (1) The pelvic region of 12 adult cadavers was dissected and analyzed.All specimens were divided in the median sagittal plane.The main goal of these dissection was to understand the fascial structures of the presacral space and measure some data correlated with the rectosacral fascia and pelvic splanchnic nerves.(2) The blunt guide pin was inserted using the technique described by Marotta into 24 pelvic-halves, the distance from the trocar to important structures in the presacral space was measured.Results (1) The fascial structures of the presacral space was multilaminar, it could be divided into five levels.(2) The rectosacral fascia was found in 11 out of 12 specimens (91.7%),it originated from the parietal presacral fascia at the level of S2 in 16.7% ,S3 in 41.7% and S4 in 33.3%.The presacral space was divided into superior and inferior portions by the rectosacral fascia.(3) Pelvic splanchnic nerves confined the dissection of the lower rectum, its length which could be used as a measure of the'sagittal safe zone' for presacral space was (22.9±3.2)mm.(4) In this study, the shortest distance from the guide pin to pelvic splanchnic nerves was (7.8 ±l.9)mm, the vertical distance to the S3/4 junction was (15.0 ±3.6)mm.Conclusion It is risky to perform the presacral approach for axial lumbar interbody fusion because of the presence of the rectosacral fascia, presacral venous plexus and the vascular variations.%目的 探讨经骶前间隙轴向腰椎椎间融合术入路的安全性.方法 (1) 12具(24侧)防腐固定成人骨盆段标本,解剖骶前间隙,观察骶前的筋膜层次,骶直肠筋膜,盆内脏神经等,测量骶直肠筋膜和盆内脏神经的相关解剖数据.(2)参照Marotta方法,模拟手术置入导针,测量导针在骶前间隙中的相关解剖学数据.结果 (1)骶前的筋膜可分为5层;(2)

  20. 浅析情景教学法在Access数据库课程教学过程中的应用%On the situational approach applied in Access database Teaching Process

    Institute of Scientific and Technical Information of China (English)

    李艳红; 苏有邦


    本文针对学生当前学习Access数据库中存在的学时少,实践性、操作性强及理论知识抽象难懂等问题,提出将情景教学法应用于Access数据库的日常实际教学中,阐述了情景教学法在Access数据库的理论和实践教学中的具体应用和优势。%In this paper,students Access database exists in the current hours less practical,operational and theoretical knowledge is abstract and difficult issues such as situational approach applied to the proposed Access database everyday practical teaching,elaborated situational approach in theory and practice of teaching Access database specific applications and advantages.

  1. La modelisation mathematique dans l'enseignement de la chimie des gaz a des eleves de la cinquieme annee du secondaire (United States)

    Gauthier, Diane

    Les problemes d'enseignement de la chimie des gaz parfaits sont donc importants. Si plusieurs etudes ont ete realisees dans le but d'identifier et d'interpreter ces problemes, aucune recherche, a notre connaissance, n'a ete realisee sur l'enseignement des lois sur les gaz parfaits. Notre recherche sur l'enseignement est donc pionniere. Elle a pour objectif general de construire et d'analyser une sequence d'enseignement de la chimie des gaz comportant diverses situations de modelisation mathematique des conduites des gaz. Les principaux objectifs specifiques sont les suivants: (1) identifier et caracteriser les situations qui provoquent une evolution des conceptions naives des eleves, evolution vers des connaissances plus adequate sur les gaz; (2) identifier et caractEriser les situations qui provoquent une evolution des connaissances mathematiques des eleves leur permettant d'interpreter convenablement les resultats des experiences, d'eprouver leurs conceptions, de donner un sens aux notions et aux relations impliquees dans les lois des gaz parfaits, lois de Boyle-Mariotte et Gay-Lussac. Une sequence d'enseignement comportant huit situations est d'eleves de secondaire V. La construction de ces situations est orientee par les recherches sur les conceptions naives des eleves, par les etudes sur l'evolution historique des conceptions sur les gaz et des pratiques scientifiques, ainsi que par les etudes theoriques et empiriques realisees en didactique des sciences et des mathematiques. La methodologie de l'ingenierie didactique (Artigue, 1998) qui constitue une application de la theorie des situations didactiques (Brousseau, 1986) est utilisee dans la construction et l'analyse des situations d'enseignement. Une analyse a priori de chacune des situations d'enseignement est effectuee; elle a pour but dexpliquer les choix des taches qui font partie des situations et de preciser la gestion didactique des situations. Diverses situations d'enseignement de la chimie ont ainsi


    This dataset will be used to illustrate various data mining techniques to biologically profile the chemical space. This dataset will be used to illustrate various data mining techniques to biologically profile the chemical space.

  3. Applying the Cultural Approach to Cognitive Development (United States)

    Gauvain, Mary; Beebe, Heidi; Zhao, Shuheng


    Cognitive development is a cultural process. More experienced cultural members and the practices, institutions, and artifacts of the culture provide support and guidance for children as they develop knowledge and thinking skills. In this article, the authors describe the value that is added to our understanding of cognitive development when…

  4. SEM in applied marketing research

    DEFF Research Database (Denmark)

    Sørensen, Bjarne Taulo; Tudoran, Ana Alina

    In this paper we discuss two SEM approaches: an exploratory structural equation modelling based on a more liberalised and inductive philosophy versus the classical SEM based on the traditional hypothetical-deductive approach. We apply these two modelling techniques to data from a consumer survey ...

  5. Applied Control Systems Design

    CERN Document Server

    Mahmoud, Magdi S


    Applied Control System Design examines several methods for building up systems models based on real experimental data from typical industrial processes and incorporating system identification techniques. The text takes a comparative approach to the models derived in this way judging their suitability for use in different systems and under different operational circumstances. A broad spectrum of control methods including various forms of filtering, feedback and feedforward control is applied to the models and the guidelines derived from the closed-loop responses are then composed into a concrete self-tested recipe to serve as a check-list for industrial engineers or control designers. System identification and control design are given equal weight in model derivation and testing to reflect their equality of importance in the proper design and optimization of high-performance control systems. Readers’ assimilation of the material discussed is assisted by the provision of problems and examples. Most of these e...

  6. Applied Ethics in Nowadays Society

    Directory of Open Access Journals (Sweden)

    Tomita CIULEI


    Full Text Available This special issue is dedicated to Nowadays Applied Ethics in Society, and falls in the field of social sciences and humanities, being hosted both theoretical approaches and empirical research in various areas of applied ethics. Applied ethics analyzes of a series of morally concrete situations of social or professional practice in order to make / adopt decisions. In the field of applied ethics are integrated medical ethics, legal ethics, media ethics, professional ethics, environmental ethics, business ethics etc. Classification-JEL: A23

  7. Analytical approaches to image orientation and stereo digitization applied in the Budnlab software. (Polish Title: Rozwiazania analityczne zwiazane z obsluga procesu orientacji zdjec oraz wykonywaniem opracowan wektorowych w programie Bundlab) (United States)

    Kolecki, J.


    The Bundlab software has been developed mainly for academic and research application. This work can be treated as a kind of a report describing the current state of the development of this computer program, focusing especially on the analytical solutions. Firstly, the overall characteristics of the software are provided. Then the description of the image orientation procedure starting from the relative orientation is addressed. The applied solution is based on the coplanarity equation parametrized with the essential matrix. The problem is reformulated in order to solve it using methods of algebraic geometry. The solution is followed by the optimization involving the least square criterion. The formation of the image block from the oriented models as well as the absolute orientation procedure were implemented using the Horn approach as a base algorithm. The second part of the paper is devoted to the tools and methods applied in the stereo digitization module. The solutions that support the user and improve the accuracy are given. Within the paper a few exemplary applications and products are mentioned. The work finishes with the concepts of development and improvements of existing functions.

  8. Studying uranium migration in natural environment: experimental approach and geochemical modeling; Etude de la migration de l'uranium en milieu naturel: approche experimentale et modelisation geochimique

    Energy Technology Data Exchange (ETDEWEB)

    Phrommavanh, V.


    The present study deals with characterizing uranium migration in a limited zone of Le Bouchet site, a former uranium ore treatment facility, which is dismantled and the rehabilitation of which is under process. Some wastes are packed in a rehabilitated disposal nearby, called the Itteville site. In the framework of the monitoring of the deposit environment (air, water, sediment) set by prefectorial decrees, a piezometer (PZPK) located downstream to the latter, has shown total dissolved uranium peaks each winter since the 1990's. PZPK collects both the interstitial water of a calcareous peat formation, between the surface and 3 m, and an alluvial aquifer near 6 m of depth. Firstly, a hydrogeochemical characterization of the site has evidenced the uranium source term, which is present in the peat soil near 0.8 m, hence excluding any leaching from the waste disposal. Actually, a few microparticles of uranium oxide and mixed uranium-thorium oxide have been detected, but they do not represent the major part of the source term. Secondly, water chemistry of the peat soil water and PZPK has been monitored every two months from 2004 to 2007 in order to understand the reasons of the seasonal fluctuations of [U]tot.diss.. Completed with geochemical modeling and a bacterial identification by 16S rDNA sequence analysis, water chemistry data showed an important sulfate-reducing bacterial activity in summertime, leading to reducing conditions and therefore, a total dissolved uranium content limited by the low solubility of uraninite U{sup IV}O{sub 2}(s). In wintertime, the latter bacterial activity being minimal and the effective pluviometry more important, conditions are more oxidant, which favors U(VI), more soluble, notably as the Ca{sub 2}UO{sub 2}(CO{sub 3}){sub 3}(aq) complex, evidenced by TRLFS. Finally, bacterial activity has been reproduced in laboratory in order to better characterize its impact on uranium solubility in the peat soil. Various parameters were tested (C sources, temperature, nutrients) to recreate conditions close and also different to those in situ. 16S rDNA sequence bacterial identifications, throughout the incubation time, have confirmed an increase of sulfate-reducing bacteria proportion. At the same time, water chemistry, as well as geochemical calculations and SEM observations and XANES analyses, have evidenced an decrease of [U]tot.diss., owing to its reduction as UO{sub 2}(s) (certainly as nano-particles). Even though the reaction mechanism could not be determined, that is to say biotic (direct uranium reduction by bacteria) or abiotic (indirect reduction), these experiments have showed that sulfate-reducing bacteria can prevail among a varied indigenous population in conditions close to those in situ. Moreover, the studied calcareous peat contains a significant amount of weddellite (CaC{sub 2}O{sub 4}.2H{sub 2}O(s)), accounting for a permanent input of oxalate ions C{sub 2}O{sub 4}{sup 2-} which can be used as C source in the course of sulfate and/or uranium reduction in the summer. (author)

  9. Thermo-mechanical behaviour modelling of particle fuels using a multi-scale approach; Modelisation du comportement thermomecanique des combustibles a particules par une approche multi-echelle

    Energy Technology Data Exchange (ETDEWEB)

    Blanc, V.


    Particle fuels are made of a few thousand spheres, one millimeter diameter large, compound of uranium oxide coated by confinement layers which are embedded in a graphite matrix to form the fuel element. The aim of this study is to develop a new simulation tool for thermo-mechanical behaviour of those fuels under radiations which is able to predict finely local loadings on the particles. We choose to use the square finite element method, in which two different discretization scales are used: a macroscopic homogeneous structure whose properties in each integration point are computed on a second heterogeneous microstructure, the Representative Volume Element (RVE). First part of this works is concerned by the definition of this RVE. A morphological indicator based in the minimal distance between spheres centers permit to select random sets of microstructures. The elastic macroscopic response of RVE, computed by finite element has been compared to an analytical model. Thermal and mechanical representativeness indicators of local loadings has been built from the particle failure modes. A statistical study of those criteria on a hundred of RVE showed the significance of choose a representative microstructure. In this perspective, a empirical model binding morphological indicator to mechanical indicator has been developed. Second part of the work deals with the two transition scale method which are based on the periodic homogenization. Considering a linear thermal problem with heat source in permanent condition, one showed that the heterogeneity of the heat source involve to use a second order method to localized finely the thermal field. The mechanical non-linear problem has been treats by using the iterative Cast3M algorithm, substituting to integration of the behavior law a finite element computation on the RVE. This algorithm has been validated, and coupled with thermal resolution in order to compute a radiation loading. A computation on a complete fuel element reflect a strong interaction between the two scales, that confirm the interest of a such model to compute the behaviour of those fuels. (author)

  10. Vygotsky in applied neuropsychology

    Directory of Open Access Journals (Sweden)

    Glozman J. M.


    Full Text Available The aims of this paper are: 1 to show the role of clinical experience for the theoretical contributions of L.S. Vygotsky, and 2 to analyze the development of these theories in contemporary applied neuropsychology. An analysis of disturbances of mental functioning is impossible without a systemic approach to the evidence observed. Therefore, medical psychology is fundamental for forming a systemic approach to psychology. The assessment of neurological patients at the neurological hospital of Moscow University permitted L.S. Vygotsky to create, in collaboration with A.R. Luria, the theory of systemic dynamic localization of higher mental functions and their relationship to cultural conditions. In his studies of patients with Parkinson’s disease, Vygotsky also set out 3 steps of systemic development: interpsychological, then extrapsychological, then intrapsychological. L.S. Vygotsky and A.R. Luria in the late 1920s created a program to compensate for the motor subcortical disturbances in Parkinson’s disease (PD through a cortical (visual mediation of movements. We propose to distinguish the objective mediating factors — like teaching techniques and modalities — from subjective mediating factors, like the individual’s internal representation of his/her own disease. The cultural-historical approach in contemporary neuropsychology forces neuropsychologists to re-analyze and re-interpret the classic neuropsychological syndromes; to develop new assessment procedures more in accordance with the patient’s conditions of life; and to reconsider the concept of the social brain as a social and cultural determinant and regulator of brain functioning. L.S. Vygotsky and A.R. Luria proved that a defect interferes with a child’s appropriation of his/her culture, but cultural means can help the child overcome the defect. In this way, the cultural-historical approach became, and still is, a methodological basis for remedial education.

  11. Modelisation de l'erosion et des sources de pollution dans le bassin versant Iroquois/Blanchette dans un contexte de changements climatiques (United States)

    Coulibaly, Issa

    Principale source d'approvisionnement en eau potable de la municipalite d'Edmundston, le bassin versant Iroquois/Blanchette est un enjeu capital pour cette derniere, d'ou les efforts constants deployes pour assurer la preservation de la qualite de son eau. A cet effet, plusieurs etudes y ont ete menees. Les plus recentes ont identifie des menaces de pollution de diverses origines dont celles associees aux changements climatiques (e.g. Maaref 2012). Au regard des impacts des modifications climatiques annonces a l'echelle du Nouveau-Brunswick, le bassin versant Iroquois/Blanchette pourrait etre fortement affecte, et cela de diverses facons. Plusieurs scenarios d'impacts sont envisageables, notamment les risques d'inondation, d'erosion et de pollution a travers une augmentation des precipitations et du ruissellement. Face a toutes ces menaces eventuelles, l'objectif de cette etude est d'evaluer les impacts potentiels des changements climatiques sur les risques d'erosion et de pollution a l'echelle du bassin versant Iroquois/Blanchette. Pour ce faire, la version canadienne de l'equation universelle revisee des pertes en sol RUSLE-CAN et le modele hydrologique SWAT ( Soil and Water Assessment Tool) ont ete utilises pour modeliser les risques d'erosion et de pollution au niveau dans la zone d'etude. Les donnees utilisees pour realiser ce travail proviennent de sources diverses et variees (teledetections, pedologiques, topographiques, meteorologiques, etc.). Les simulations ont ete realisees en deux etapes distinctes, d'abord dans les conditions actuelles ou l'annee 2013 a ete choisie comme annee de reference, ensuite en 2025 et 2050. Les resultats obtenus montrent une tendance a la hausse de la production de sediments dans les prochaines annees. La production maximale annuelle augmente de 8,34 % et 8,08 % respectivement en 2025 et 2050 selon notre scenario le plus optimiste, et de 29,99 % en 2025 et 29,72 % en 2050 selon le scenario le plus pessimiste par rapport a celle

  12. Applied statistical thermodynamics

    CERN Document Server

    Lucas, Klaus


    The book guides the reader from the foundations of statisti- cal thermodynamics including the theory of intermolecular forces to modern computer-aided applications in chemical en- gineering and physical chemistry. The approach is new. The foundations of quantum and statistical mechanics are presen- ted in a simple way and their applications to the prediction of fluid phase behavior of real systems are demonstrated. A particular effort is made to introduce the reader to expli- cit formulations of intermolecular interaction models and to show how these models influence the properties of fluid sy- stems. The established methods of statistical mechanics - computer simulation, perturbation theory, and numerical in- tegration - are discussed in a style appropriate for newcom- ers and are extensively applied. Numerous worked examples illustrate how practical calculations should be carried out.

  13. Modelling and inversion of 3D complex kinematic data; Modelisation et inversion de donnees cinematiques complexes en 3D

    Energy Technology Data Exchange (ETDEWEB)

    Clarke, R.


    Reflection tomography can determine velocity models containing lateral velocity variations and reflectors of arbitrary shapes; in order to access the kinematic data, a 3D zero offset approach to the SMART (Sequential Migration Aided Reflection Tomography) method, an original method of migration velocity analysis, is adopted. The approach involves interpreting kinematic data in the post-stack depth migrated cube and then de-migrating the horizons by two-point ray-tracing. A fast and robust two-point ray-tracer is developed, which can recover multi-valued kinematic data from complex geological structures. An original formulation for 3D reflection tomography is proposed, which can reliably take into account multivalued travel times

  14. Modelling of fractured reservoirs. Case of multi-scale media; Modelisation des reservoirs fractures. Cas des milieux multi-echelles

    Energy Technology Data Exchange (ETDEWEB)

    Henn, N.


    Some of the most productive oil and gas reservoirs are found in formations crossed by multi-scale fractures/faults. Among them, conductive faults may closely control reservoir performance. However, their modelling encounters numerical and physical difficulties linked with (a) the necessity to keep an explicit representation of faults through small-size grid blocks, (b) the modelling of multiphase flow exchanges between the fault and the neighbouring medium. In this thesis, we propose a physically-representative and numerically efficient modelling approach in order to incorporate sub-vertical conductive faults in single and dual-porosity simulators. To validate our approach and demonstrate its efficiency, simulation results of multiphase displacements in representative field sector models are presented. (author)

  15. Two-phase pulsatile flows through porous conical tubes of small diameters. Modelisation of the blood microcirculation. (United States)

    Zeggwagh, G; Bellet, D


    A theoretical study concerning two-component fluid pulsating flow through porous conical ducts is presented. The model corresponds to blood flows through small diameter porous conical vessels. This approach is based on a finite difference method. The physical hypothesis used were based on findings from simultaneous visualization methods. The influence of geometrical, hydrodynamical and structural parameters is systematically examined and related to velocity profiles, hydrostatic pressure.

  16. El hipertexto en la Enseñanza Media en Chile: ¿Es pertinente aplicar los enfoques textuales tradicionales? Hypertext in Secondary School in Chile: ¿It is pertinent apply traditional textual approaches?

    Directory of Open Access Journals (Sweden)

    Teresa Ayala Pérez


    Full Text Available Los textos digitales constituyen parte importante de la comunicación en la sociedad de la información y recientemente han sido incluidos en los programas de Lenguaje y Comunicación de E.M. en Chile. Ante esta situación, cabe preguntarse si los tradicionales enfoques textuales, elaborados a partir del texto impreso en los años 70 y 80 y utilizados actualmente en Enseñanza Media, resultan aplicables al hipertexto. En este trabajo se describen algunos rasgos de este tipo de texto y se reflexiona sobre la posibilidad de aplicar al hipertexto los conceptos de criterios de textualidad, competencia textual y tipología textual en el ámbito escolar.Digital texts are an important part of communication in the information society and they have been recently included as Language and Communication contents in Chile. In this situation, it is possible to wonder if traditional textual approaches made from the printed text at 70's and 80's and used now in secondary school, are pertinent in the case of hypertext. This paper describes some text features and attempt to raise the possibility of applying hypertext concepts like textuality, textual competence and text typology in secondary education.

  17. Modelling of the hydrodynamic behaviour of a decontamination foam; Modelisation du comportement hydrodynamique d'une mousse de decontamination

    Energy Technology Data Exchange (ETDEWEB)

    Faury, M.; Fournel, B. [CEA Cadarache, Dept. d' Entreposage et de Stockage des Dechets, 13 - Saint-Paul-lez-Durance (France)


    Decontamination of large components of nuclear power plants (refrigerants, vapor generators, effluents storage tanks...) produces an important volume of secondary effluents. The use of decontamination foams is an alternative allowing a significant diminution of this volume (about of a factor ten). The aim of this work is to propose models which could be applied by an industrialist in order to anticipate the behaviour of a foam flowing out in a component of any geometry and simplifying then the pre-study steps. (O.M.)

  18. Toward an Applied Administrative Science. (United States)

    Dunbar, Roger L. M.


    A study of 65 articles from the 1981 volumes of "Administrative Science Quarterly" and "Harvard Business Review," using smallest space analysis, found that the few studies adopting subjective (instead of objective) approaches to analyzing organizational change were most likely to provide a basis for an applied administrative…

  19. Modeling and numerical study of transfers in fissured environments; Modelisation et etude numerique des transferts en milieux fissures

    Energy Technology Data Exchange (ETDEWEB)

    Granet, S.


    Oil recovery from fractured reservoirs plays a very important role in the petroleum industry. Some of the world most productive oil fields are located in naturally fractured reservoirs. Modelling flow in such a fracture network is a very complex problem. This is conventionally done using a specific idealized model. This model is based on the Warren and Root representation and on a dual porosity, dual permeability approach. A simplified formulation of matrix-fracture fluid transfers uses a pseudo-steady-state transfer equation involving a constant exchange coefficient. Such a choice is one of the main difficulties of this approach. To get a better understanding of the simplifications involved in the dual porosity approach a reference model must be available. To obtain such a fine description, we have developed a new methodology. This technique called 'the fissure element methodology' is based on a specific gridding of the fractured medium. The fissure network is gridded with linear elements coupled with an unstructured triangular grid of matrix. An appropriate finite volume scheme has been developed to provide a good description of the flow. The numerical development of is precisely described. A simulator has been developed using this method. Several simulations have been realised. Comparisons have been done with different dual-porosity dual-permeability models. A reflexion concerning the choice of the exchange coefficient used in the dual porosity model is then proposed. This new tool has permit to have a better understanding of the production mechanisms of a complex fractured reservoir. (author)

  20. Numerical modeling of transferred arc melting bath heating; Modelisation numerique du chauffage de bains par arc transfere

    Energy Technology Data Exchange (ETDEWEB)

    Bouvier, A. [Electricite de France, 77 - Moret sur Loing (France). Direction des Etudes et Recherches; Trenty, L.; Guillot, J.B. [Ecole Centrale de Paris, Laboratoire EM2C. CNRS, 92 - Chatenay-Malabry (France); Delalondre, C. [Electricite de France (EDF), 78 - Chatou (France). Direction des Etudes et Recherches


    This paper presents the modeling of a transferred electric arc inside a bath of melted metal. After a recall of the context of the study, the problem of the modeling, which involves magnetohydrodynamic coupling inside the arc and the bath, is described. The equations that govern the phenomena inside the arc and the bath are recalled and the approach used for the modeling of the anode region of the arc is explained using a 1-D sub-model. The conditions of connection between arc and bath calculations are explained and calculation results obtained with a 200 kW laboratory furnace geometry are presented. (J.S.) 8 refs.

  1. Modelling of the generation phase of an absorption cooling cycle operating intermittently; Modelisation de la phase generation d'un cycle de refrigeration par absorption solaire a fonctionnement intermittent

    Energy Technology Data Exchange (ETDEWEB)

    Boukhchana, Yasmina; Fellah, Ali; Ben Brahim, Ammar [Unite de Recherche, Thermodynamique Appliquee (99/UR/11-21), Universite de Gabes, Ecole Nationale d' ingenieurs, 6072 Gabes (Tunisia)


    No abstract prepared. [French] La modelisation en regime dynamique de la phase generation d'une installation frigorifique a absorption solaire a fonctionnement intermittent utilisant le couple ammoniac/eau a ete elaboree. L'etude basee sur l'intermittence du fonctionnement a permis d'elaborer, a travers les bilans matieres et thermiques, un modele thermodynamique reliant les temperatures, les debits et les fractions massiques dans les differents compartiments. Des journees ensoleillees representatives des quatre saisons de l'annee ont ete considerees. Les variations du taux d'ensoleillement, des temperatures et des concentrations ont ete explorees. Les resultats ont montre, moyennant les hypotheses adoptees en particulier a pression de fonctionnement constante, que la demarche proposee a permis d'avoir une temperature de generation autour de 135 C et une temperature de condensation de 60 C. Ces temperatures sont atteinte par l'adaptation de la convection naturelle a l'air pour le fonctionnement du condenseur. (orig.)

  2. Modelling of GMA welding in short-arc mode; Modelisation du soudage MIG/MAG en mode short-arc

    Energy Technology Data Exchange (ETDEWEB)

    Planckaert, J.P


    Nowadays there is a lot of welding processes giving an answer to the great diversity of joints to realize and to the characteristics of the metals employed. The first chapter describes the different power sources used in welding. After that, a more detailed explanation of arc welding is given. Finally we present the design of a welding test bed. One can, of course, use an empirical approach to optimize a process. Nevertheless there are advantages in choosing an analytical approach since we can expect significant progress in the understanding of the dynamical interactions in the arc. That's why we present in the second chapter the theoretical knowledge concerning the behaviour of the molten metal transferred during Gas Metal Arc Welding. This work involves as well an experimental aspect required for the elaboration of the databases used to build the model. The recordings were made at CTAS on a test bed equipped with an acquisition system for measuring voltage, current, wire feed speed and high speed videos. The third chapter presents our research of a segmentation method to measure some relevant quantities. We propose a software sensor based on the active contour theory and we show good results on experimental movies. An adjustment step of the model is needed and described in the fourth chapter. The created simulator allows us to interpret some important phenomena in welding, to make a sensitive study 'without risk' and to give theoretical defect signatures. (author)

  3. 从应用语言学角度探讨英语折中主义教学法%English Eclectic Teaching Approach to Study from the Angle of Applied Linguistics

    Institute of Scientific and Technical Information of China (English)

    王媛媛; 段胜峰


    Advantages of eclectic teaching approach is to learn widely from others'strong points, trying to swallow anything and everything, from a variety of teaching methods in the teaching of drawing, DOM, is a product of deduction and induction, ratio-nal and empirical combination. Its shortcoming is that does not provide any reference standard, to decide which kind of teaching theory and teaching skills, reasonable absorption and rejection and no corresponding provisions given theory. College English is an important language teaching, is the focus of Applied Linguistics, but for now, College English very difficult for English practi-cal application needs. Application of the eclectic approach in College English teaching, help to make certain to improve the effec-tiveness of teaching, development also can promote the eclectic teaching method.%折中教学法的优点是博采众长,兼收并蓄,试图从各种教学方法中吸取教学所长,避其所短,是一种演绎与归纳、理性与实证相结合的产物。其不足之处在于并没有提供任何参考标准,使其断定哪种教学理论或教学技巧好,同时也没有给出相应规定的合理吸收及排斥的理论。高校英语作为一门重要的外语教学,是应用语言学研究的重点,但是就目前来说,高校英语非常难以对英语的实际应用需求进行满足。其中折中主义教学法在高校英语教学中的应用,有助于对其教学有效性进行一定的提高,同时还可以促进折中主义教学法的发展。

  4. Analysis and modelling of the fuels european market; Analyse et modelisation des prix des produits petroliers combustibles en europe

    Energy Technology Data Exchange (ETDEWEB)

    Simon, V


    The research focus on the European fuel market prices referring to the Rotterdam and Genoa spot markets as well the German, Italian and French domestic markets. The thesis try to explain the impact of the London IPE future market on spot prices too. The mainstream research has demonstrated that co-integration seems to be the best theoretical approach to investigate the long run equilibrium relations. A particular attention will be devoted to the structural change in the econometric modelling on these equilibriums. A deep analysis of the main European petroleum products markets permit a better model specification concerning each of these markets. Further, we will test if any evidence of relations between spot and domestic prices could be confirmed. Finally, alternative scenarios will be depicted to forecast prices in the petroleum products markets. The objective is to observe the model reaction to changes crude oil prices. (author)

  5. Modeling of pollution aerosols in Ile-de-France; Modelisation des aerosols de pollution en Ile-de-France

    Energy Technology Data Exchange (ETDEWEB)

    Hodzic, A


    The modeling of aerosols is a major stake in the understanding of the emission processes and evolution of particulates in the atmosphere. However, the parameterizations used in today's aerosol models still comprise many uncertainties. This work has been motivated by the need of better identifying the weaknesses of aerosols modeling tools and by the necessity of having new validation methods for a 3D evaluation of models. The studies have been carried out using the CHIMERE chemistry-transport model, which allows to simulate the concentrations and physico-chemical characteristics of pollution aerosols at the European scale and in Ile-de-France region. The validation approach used is based on the complementarity of the measurements performed on the ground by monitoring networks with those acquired during the ESQUIF campaign (study and simulation of air quality in Ile-de-France), with lidar and photometric measurements and with satellite observations. The comparison between the observations and the simulations has permitted to identify and reduce the modeling errors, and to characterize the aerosol properties in the vicinity of an urban area. (J.S.)

  6. In-situ Modelisation of a Greenhouse Climate Including Sensible Heat, Water Vapour and CO2 Balances

    Directory of Open Access Journals (Sweden)

    Bibi-Triki N.


    Full Text Available While thermal structures such as greenhouses are complex to model under transient conditions because of coupled heat and mass (H2O and CO2 exchanges between their different parts, systems theory allows a simple analysis of the input/output behaviour of the model. In particular, parameters of the reduced dynamic models can be derived from in-situ measurements on these systems. This paper describes an application of the systems approach to a greenhouse climate model which incorporates CO2 balance, crop transpiration and photosynthesis and the effects of heating, CO2 enrichment, natural ventilation and evaporative cooling. In a first stage, system parameters such as the equivalent thermal mass, the wind dependent coefficient of natural ventilation and the various heat exchange coefficients were identified in situ from sequences of input-output data concerning the heat and water vapour balance, recorded over the crop production period from December to July. Good agreement between measured and computed values of air temperature, air humidity was observed. In a second stage, we have considered simultaneously the sensible heat, water vapour and CO2 exchanges and tested the model against experimental data measured using a commercial greenhouse climate control computer. The identified values of the physical and physiological parameters are close the theoretical values and the accuracy of temperature, humidity and CO2 content is rather good.

  7. Civil engineering: EDF needs for concrete modelling; Genie civile: analyse des besoins EDF en modelisation du comportement des betons

    Energy Technology Data Exchange (ETDEWEB)

    Didry, O.; Gerard, B.; Bui, D. [Electricite de France (EDF), Direction des Etudes et Recherches, 92 - Clamart (France)


    Concrete structures which are encountered at EDF, like all civil engineering structures, age. In order to adapt the maintenance conditions of these structures, particularly to extend their service life, and also to prepare constructions of future structures, tools for predicting the behaviour of these structures in their environment should be available. For EDF the technical risks are high and consequently very appropriate R and D actions are required. In this context the Direction des Etudes et Recherches (DER) has developed a methodology for analysing concrete structure behaviour modelling. This approach has several aims: - making a distinction between the problems which refer to the existing models and those which require R and D; - displaying disciplinary links between different problems encountered on EDF structures (non-linear mechanical, chemical - hydraulic - mechanical coupling, etc); - listing of the existing tools and positioning the DER `Aster` finite element code among them. This document is a state of the art of scientific knowledge intended to shed light on the fields in which one should be involved when there is, on one part a strong requirement on the side of structure operators, and on the other one, the present tools do not allow this requirement to be satisfactorily met. The analysis has been done on 12 scientific subjects: 1) Hydration of concrete at early ages: exothermicity, hardening, autogenous shrinkage; 2) Drying and drying shrinkage; 3) Alkali-silica reaction and bulky stage formation; 4) Long term deterioration by leaching; 5) Ionic diffusion and associated attacks: the chlorides case; 6) Permeability / tightness of concrete; 7) Concretes -nonlinear behaviour and cracking (I): contribution of the plasticity models; 8) Concretes - nonlinear behaviour and cracking (II): contribution of the damage models; 9) Concretes - nonlinear behaviour and cracking (III): the contribution of the probabilistic analysis model; 10) Delayed behaviour of

  8. Modeling of urban atmospheric pollution and impact on health; Modelisation de la pollution atmospherique urbaine et impact sur la sante

    Energy Technology Data Exchange (ETDEWEB)

    Myrto, Valari


    The goal of this dissertation, is to develop a methodology that provides an improved knowledge of the associations between atmospheric contaminant concentrations and health impact. The propagation of uncertainties from input data to the output concentrations through a Chemistry Transport Model was first studied. The influence of the resolutions of meteorological parameters and emissions data were studied separately, and their relative role was compared. It was found that model results do not improve linearly with the resolution of emission input. A critical resolution was found, beyond which model error becomes higher and the model breaks down. Based on this first investigation concerning the direct down scaling, further research focused on sub grid scale modeling. Thus, a statistical down scaling approach was adopted for the modeling of sub grid-scale concentration variability due to heterogeneous surface emissions. Emission fractions released from different types of sources (industry, roads, residential, natural etc.) were calculated from a high-resolution emission inventory. Then emission fluxes were mapped on surfaces emitting source-specific species. Simulations were run independently over the defined micro-environments allowing the modeling of sub grid-scale concentration variability. Sub grid scale concentrations were therefore combined with demographic and human activity data to provide exposure estimates. The spatial distribution of human exposure was parameterized through a Monte-Carlo model. The new information concerning exposure variability was added to an existing epidemiological model to study relative health risks. A log-linear Poisson regression model was used for this purpose. The principal outcome of the investigation was that a new functionality was added to the regression model which allows the dissociation of the health risk associated with each pollutant (e.g. NO{sub 2} and PM{sub 2.5}). (author)

  9. Immiscible displacements in vuggy carbonates: experiments and simulation; Deplacements immiscibles dans des carbonates vacuolaires: experimentation et modelisation

    Energy Technology Data Exchange (ETDEWEB)

    Moctezuma Berthier, A.E.


    for the vuggy field even if it is not connected. On the core scale, we applied the reconstruction method to generate porosity fields by using the experimental charts obtained by X-Ray CT scanner. This method was satisfactory for an isotropic rock. Macroscopic conductivity is only slightly influenced by the porosity distribution; the empirical model on the pore scale is consistent with experimental measurements, and calculations on the reconstructed porosity field also lead to a very good agreement. (author)

  10. Applying evolutionary anthropology. (United States)

    Gibson, Mhairi A; Lawson, David W


    Evolutionary anthropology provides a powerful theoretical framework for understanding how both current environments and legacies of past selection shape human behavioral diversity. This integrative and pluralistic field, combining ethnographic, demographic, and sociological methods, has provided new insights into the ultimate forces and proximate pathways that guide human adaptation and variation. Here, we present the argument that evolutionary anthropological studies of human behavior also hold great, largely untapped, potential to guide the design, implementation, and evaluation of social and public health policy. Focusing on the key anthropological themes of reproduction, production, and distribution we highlight classic and recent research demonstrating the value of an evolutionary perspective to improving human well-being. The challenge now comes in transforming relevance into action and, for that, evolutionary behavioral anthropologists will need to forge deeper connections with other applied social scientists and policy-makers. We are hopeful that these developments are underway and that, with the current tide of enthusiasm for evidence-based approaches to policy, evolutionary anthropology is well positioned to make a strong contribution.

  11. Soil-fluid interaction modeling in cross-well seismic experience; Modelisation du couplage sol-fluide pour la sismique entre puits

    Energy Technology Data Exchange (ETDEWEB)

    Baroni, A.


    Simulation of a cross-well experience is difficult, due to the generation of guided waves in the source containing well and in the receiver containing well. A hybrid sub-structural technique is proposed for the experience modelling, where the two holes are independently considered, using analytical and numerical approaches. The unknown quantity of the global problem, describing the global interaction between all the domains, is the stress vector applied on all the interfaces; this problem requires the solution of local problems describing local equilibrium in each domain. The boundary integral equation method in elastic domains, and a variational formulation in fluid domains, are used, assuming the existence of the zeroth guided mode, known as tube wave, at the fluid-solid interface

  12. Modern applied U-statistics

    CERN Document Server

    Kowalski, Jeanne


    A timely and applied approach to the newly discovered methods and applications of U-statisticsBuilt on years of collaborative research and academic experience, Modern Applied U-Statistics successfully presents a thorough introduction to the theory of U-statistics using in-depth examples and applications that address contemporary areas of study including biomedical and psychosocial research. Utilizing a "learn by example" approach, this book provides an accessible, yet in-depth, treatment of U-statistics, as well as addresses key concepts in asymptotic theory by integrating translational and cross-disciplinary research.The authors begin with an introduction of the essential and theoretical foundations of U-statistics such as the notion of convergence in probability and distribution, basic convergence results, stochastic Os, inference theory, generalized estimating equations, as well as the definition and asymptotic properties of U-statistics. With an emphasis on nonparametric applications when and where applic...

  13. Modelisation de l'instabilite fluidelastique d'un faisceau de tubes soumis a un ecoulement diphasique transverse (United States)

    Sawadogo, Teguewinde

    . Stability tests were conducted in the second stage of the project to validate the theoretical model. The two phase damping, the added mass and the critical velocity for fluidelastic instability were measured in two-phase flow. A viscoelastic damper was designed to vary the damping of the flexible tube and thus measure the critical velocity for a certain range of the mass-damping parameter. A new formulation of the added mass as a function of the void fraction was proposed. This formulation has a better agreement with the experimental results because it takes into account the reduction of the void fraction in the vicinity of the tubes in a rotated triangular tube array. The experimental data were used to validate the theoretical results of the quasi-steady model. The validity of the quasi-steady model for two-phase flow was confirmed by the good agreement between its results and the experimental data. The time delay parameter determined in the first stage of the project has improved significantly the theoretical results, especially for high void fractions (90%). However, the model could not be verified for void fractions lower or equal to 50% because of the limitation of the water pump capability. Further studies are consequently required to clarify this point. However, this model can be used to simulate the flow induced vibrations in steam generators' tube bundles as their most critical parts operate at high void fractions (≥ 60%). Having verified the quasi-steady model for high void fractions in two-phase flow, the third and final stage of the project was devoted to the development of a computer code for simulating flow induced vibrations of a steam generator tube subjected to fluidelastic and turbulence forces. This code was based on the ABAQUS finite elements code for solving the equation of motion of the fluid-structure system, and a development of a subroutine in which the fluid forces are calculated and applied to the tube. (Abstract shortened by UMI.)

  14. Modeling of ultrasonic propagation in a diffusing metallurgical structure, application to NDC; Modelisation de la propagation ultrasonore dans une structure metallurgique diffusante, application au CND

    Energy Technology Data Exchange (ETDEWEB)

    Dorval, V.


    Scattering phenomena can interfere with the ultrasonic non destructive testing of certain materials. It occurs for example in the testing of certain types of steels used in nuclear power plants, or of titanium alloys used in aeronautics. The scattering of ultrasonic waves by the microstructure of those materials induces structural noise and attenuation, which can have a significant impact on detection performances. This thesis deals with the modeling and computing of those phenomena. A model is used to determine the scattering properties of a metal, based on its microstructure. This model was adapted to different categories of metals. A method to compute structural noise based on this model was developed. It relies on the pencil method to perform semi-analytical computations of tridimensional ultrasonic fields. An original approach is used to limit the time necessary to compute noise signal. The computation is based on outputs of the model. This approach is based on the single scattering approximation. Noise signals computed using this method were compared to experimental results. Those comparisons confirm the relevance of the method. They also illustrate the importance of interference phenomena in structural noise. A second computation method that takes into account multiple scattering has been studied. It is based on a Monte-Carlo method applied to the radiative transfer theory. (author)

  15. Modelisation de l'interaction entre une impulsion laser ultrabreve et une nanostructure plasmonique en milieu aqueux (United States)

    Boulais, Etienne

    There is still a limited understanding of the basic mechanisms and processes triggered by laser irradiation that lead to the damaging of the surrounding structures. In particular, there exists for the moment no complete modelling of the process that includes all potential sources of cellular damage, including temperature rise, plasma generation, pressure wave emission and vapor bubble formation. This thesis presents such a modelling, with the cell environment emulated by a much simpler aqueous medium. Water is used as its optical, mechanical and thermal characteristic are similar enough to the cell environment to enable the transposition of the results and tendencies observed in water to this medium. Modelling consists in a continuous medium based approach that uses coupled partial differential equations to simulate the nanostructure-water system's response to an ultrafast laser pulse. The time-dependant field distribution in the system is simulated using classical electromagnetic theory, while the temperature in the nanostructure is calculated using a two-temperature model. Generation and heating of a plasma in the nanostructure's vicinity from photoionization and impact ionization in the near-field, as well as from photothermal emission from the nanostructure at the metal interface are also included. This plasma locally modifies the refractive index, which alters the simulated optical response of the system. Energy relaxation from this plasma as well as heat conduction from the nanostructure's lattice transfer energy to the water, which dynamics and thermodynamics evolutions are simulated from hydrodynamic and energy conservation equations. Modelling is used for analyzing the interaction of a near-infrared ultrafast laser pulse (45 fs, 800 nm, 200 mJ/cm2) with two distinct systems : a 100nm gold nanoparticle and a 10x41 nm2 gold nanorod. The gold nanoparticle shows a plasmon resonance at a ˜550 nm wavelength, and is thus slightly off-resonance at the 800 nm

  16. First principles simulation of the electrochemical behaviour of lithium battery materials; Modelisation du comportement electrochimique de materiaux pour batteries au lithium a partir de calculs de premiers principes

    Energy Technology Data Exchange (ETDEWEB)

    Rocquefelte, X.


    The functioning of a positive electrode in a lithium battery is based on the reversible intercalation of lithium. In some cases, such a reaction can lead to important structural modifications and therefore to an amorphization of the material. A theoretical approach is presented here that leads to structural predictions and simulations of electrochemical behaviour of positive electrode materials. In the first part, DFT (Density Functional Theory) formalisms and the respective advantages of FLAPW (Full potential Linearized Augmented Plane Waves) and PP/PW (Pseudopotential / Plane Waves) methods are discussed. In the second part are given some fundamental electrochemistry considerations related to the intercalation process, thermodynamics aspects and relationships with electronic structure. Then, an approach combining experimental data and geometry optimisation of structural hypotheses is given. This approach was first applied to a model compound LiMoS{sub 2}, and has been then generalised to systems of industrial interest such as Li{sub x}V{sub 2}O{sub 5} (0 {<=} x {<=} 3). The simulated X-ray diagrams of the optimised structures for LiMoS{sub 2} and {omega} - Li{sub 3}V{sub 2}O{sub 5} are in good agreement with experimental data. In the case of Li{sub x}V{sub 2}O{sub 5}, the first discharge curves starting from {alpha} - V{sub 2}O{sub 5} and {gamma}' - V{sub 2}O{sub 5} were then successfully simulated. A chemical bond analysis was carried out to help understand the origin of the distortion in LiMoS{sub 2} and the voltage variations in the electrochemical curves of Li{sub x}V{sub 2}O{sub 5}. This study clearly demonstrates that an approach combining first-principle calculations and available experimental data is invaluable in the structure determination of poorly crystallized compounds. Such a procedure contributes to the understanding of the phase transitions induced by the lithium intercalation in vanadium oxide compounds and can really be used in the research

  17. Sectional and applied anatomy of pterygopalatine fossa far operative approach%翼腭窝手术入路的断层与应用解剖学研究

    Institute of Scientific and Technical Information of China (English)

    郑海宁; 吴樾; 吕杨波; 于涌; 刘庚辰; 王平; 李云生; 翟丽东


    Objective: To supply the evidence of applied anatomy of new operative route of pterygopalatine fossa with improved ceUoidin embedding techniques. Methods: Take the anterior bases of 30 specimens of dead adult heads first. Then,after series of processes like decalcification and dehydration we make three-dimensional continued thin sections of 0.25 mm. At the same time we measure 80 sides of cardaveric heads. Results: The appearance of pterygopalatine fossa is multiplex,except for triangle,there are arc-shape、transverse"S"-shape,chock-shape ,"L"shape,dumbbell-shape,cosh-shapc,assurgent narrow strip shape. The thickness of medial wall ofpterygopalatiue fessa in middle nasal meatus is (1.95±0.66) mm (left),(1.97±0.74) mm(right).The distance from posterior edge of the aperture of maxillary sinus to pterygopalatine fossa is (11.25±1.95) mm(left) (11.22±1.96) mm (right). Conchision: The now approach of the operation doesn't pass maxillary sinus,the instruments can be used to go in the middle nasal meatus until the medial wall of pterygopalatine fossa,then open the thin piece ofboue,enter the pterygopalatine fossa directly.%目的:用改进火棉胶包埋技术,为翼腭窝新型手术入路提供应用解剖学依据.方法:固定成人尸头标本30例,取其前颅底.标本经脱钙、脱水等系列处理,分别行三维连续薄切片,厚度0.25 mm.同时对80侧干燥骨进行测量.结果:翼腭窝形态多样,除有三角形外,还有弧形、横置"S"形、楔形、"L"形、哑铃形、短棒状或斜向外上的窄长条形.翼腭窝在中鼻道处内侧壁厚度为(1.95±0.66)mmm(左),(1.97±0.74)mm(右).在中鼻道处上颌窦口后缘至翼腭窝距离(11.25±1.95)mm(左),(11.22±1.96)mm(右).结论:新型手术入路不经过上颌窦,运用器械从中鼻道深入至翼腭窝的内侧壁深度,打开薄骨板,直接进入翼腭窝,由此处入路手术创伤小、出血少、安全、术后并发症少.

  18. Perspectives on Applied Ethics



    Applied ethics is a growing, interdisciplinary field dealing with ethical problems in different areas of society. It includes for instance social and political ethics, computer ethics, medical ethics, bioethics, envi-ronmental ethics, business ethics, and it also relates to different forms of professional ethics. From the perspective of ethics, applied ethics is a specialisation in one area of ethics. From the perspective of social practice applying eth-ics is to focus on ethical aspects and ...

  19. Advances in Applied Mechanics



    Advances in Applied Mechanics draws together recent significant advances in various topics in applied mechanics. Published since 1948, Advances in Applied Mechanics aims to provide authoritative review articles on topics in the mechanical sciences, primarily of interest to scientists and engineers working in the various branches of mechanics, but also of interest to the many who use the results of investigations in mechanics in various application areas, such as aerospace, chemical, civil, en...

  20. Applied Neuroscience Laboratory Complex (United States)

    Federal Laboratory Consortium — Located at WPAFB, Ohio, the Applied Neuroscience lab researches and develops technologies to optimize Airmen individual and team performance across all AF domains....

  1. Contribution to the modeling and the identification of haptic interfaces; Contribution a la modelisation et a l'identification des interfaces haptiques

    Energy Technology Data Exchange (ETDEWEB)

    Janot, A


    This thesis focuses on the modeling and the identification of haptic interfaces using cable drive. An haptic interface is a force feedback device, which enables its user to interact with a virtual world or a remote environment explored by a slave system. It aims at the matching between the forces and displacements given by the user and those applied to virtual world. Usually, haptic interfaces make use of a mechanical actuated structure whose distal link is equipped with a handle. When manipulating this handle to interact with explored world, the user feels the apparent mass, compliance and friction of the interface. This distortion introduced between the operator and the virtual world must be modeled and identified to enhance the design of the interface and develop appropriate control laws. The first approach has been to adapt the modeling and identification methods of rigid and localized flexibilities robots to haptic interfaces. The identification technique makes use of the inverse dynamic model and the linear least squares with the measurements of joint torques and positions. This approach is validated on a single degree of freedom and a three degree of freedom haptic devices. A new identification method needing only torque data is proposed. It is based on a closed loop simulation using the direct dynamic model. The optimal parameters minimize the 2 norms of the error between the actual torque and the simulated torque assuming the same control law and the same tracking trajectory. This non linear least squares problem dramatically is simplified using the inverse model to calculate the simulated torque. This method is validated on the single degree of freedom haptic device and the SCARA robot. (author)

  2. Depth Averaged Equations Applied To Study of Defense Structures Effects On Dense Avalanche Flows (United States)

    Naaim, M.; Bouvet-Naaim, F.; Faug, T.; Lachamp, P.

    Avalanche zoning and protection devices are the complementary tools used to assess avalanche risk and protect persons and human activities in mountainous areas. Despite the intensive use of defense structures as protection against avalanches, their hydraulic and structural effects are not well known. Many structures were designed empirically using expert knowledge or knowledge developed in other domain such as hydraulic. Defence structures effects in terms of energy dissipation, deviation and snow retention are difficult to study in situ. The cost and difficulties of experiments, the danger and the weak annual number of avalanches in a given site, are the reasons why scientists oriented their research towards the use of numerical or laboratory physical models. This paper presents and discuss the possibilities to use depth averaged equations to study dense avalanche flows around defence structures. The used numerical resolu- tion method is based on an upwind numerical scheme. Equations are integrated on each cell of the mesh and the numerical fluxes are calculated thanks to a simplified Riemann solver where the retained solution is obtained as a combination of shock and rarefaction founctions. This allows taking into account the topography variation and jets and surges presence. These two characteristics are needed because both exper- imental and in situ observations showed a significant topography modifications and jets and surges formations during interaction between avalanche flows and structures. The case of vertical surfaces such as those made of concrete destined to deviate flows are treated by appropriated boundary condition functions. A discussion about the best way to integrate defence structures in such model is presented and discussed. This modelisation has, in a first time, been tested on analytical solutions and on experimen- tal laboratory scale model results. These tests have shown the capacity of this model, despite the strong hypothesis, to

  3. Thermal design of horizontal tube boilers. Numerical and experimental investigation; Modelisation thermique de bouilleurs a tubes horizontaux. Etude numerique et validation experimentale

    Energy Technology Data Exchange (ETDEWEB)

    Roser, R.


    This work concerns the thermal design of kettle reboilers. Current methods are highly inaccurate, regarded to the correlations for external heat transfer coefficient at one tube scale, as well as to two-phase flow modelling at boiler scale. The aim of this work is to improve these thermal design methods. It contains an experimental investigation with typical operating conditions of such equipment: an hydrocarbon (n-pentane) with low mass flux. This investigation has lead to characterize the local flow pattern through void fraction measurements and, from this, to develop correlations for void fraction, pressure drop and heat transfer coefficient. The approach is original, since the developed correlations are based on the liquid velocity at minimum cross section area between tubes, as variable characterizing the hydrodynamic effects on pressure drop and heat transfer coefficient. These correlations are shown to give much better results than those suggested up to now in the literature, which are empirical transpositions from methods developed for inside tube flows. Furthermore, the numerical code MC3D has been applied using the correlations developed in this work, leading to a modeling of the two-phase flow in the boiler, which is a significant progress compared to current simplified methods. (author)

  4. Material characterization and non destructive testing by ultrasounds; modelling, simulation and experimental validation; Caracterisation des materiaux et controle non destructif par ultrasons; modelisation, simulation et validation experimentale

    Energy Technology Data Exchange (ETDEWEB)

    Noroy-Nadal, M.H


    This memory presents the research concerning the characterization of materials and the Non Destructive Testing (N.D.T) by ultrasonics. The different topics include three steps: modeling, computations and experimental validation. The studied materials concern mainly metals. The memory is divided in four parts. The first one concerns the characterization of materials versus temperature. The determination of the shear modulus G(T) is especially studied for a large temperature range, and around the melting point. The second part is devoted to studies by photothermal devices essentially focused on the modeling of the mechanical displacement and the stress field in coated materials. In this particular field of interest, applications concern either the mechanical characterization of the coating, the defect detection in the structure and finally the evaluation of the coating adhesion. The third section is dedicated to microstructural characterization using acoustic microscopy. The evaluation of crystallographic texture is especially approached, for metallic objects obtained by forming. Before concluding and pointing out some perspectives to this work, the last section concerns the introduction of optimization techniques, applied to the material characterization by acoustic microscopy. (author)

  5. What are applied ethics? (United States)

    Allhoff, Fritz


    This paper explores the relationships that various applied ethics bear to each other, both in particular disciplines and more generally. The introductory section lays out the challenge of coming up with such an account and, drawing a parallel with the philosophy of science, offers that applied ethics may either be unified or disunified. The second section develops one simple account through which applied ethics are unified, vis-à-vis ethical theory. However, this is not taken to be a satisfying answer, for reasons explained. In the third section, specific applied ethics are explored: biomedical ethics; business ethics; environmental ethics; and neuroethics. These are chosen not to be comprehensive, but rather for their traditions or other illustrative purposes. The final section draws together the results of the preceding analysis and defends a disunity conception of applied ethics.

  6. Bologna Process: Apply or Not Apply

    Directory of Open Access Journals (Sweden)

    Muzaffer ELMAS


    Full Text Available There are lots of studies carried on education and training all over the world. U.S., Japan, Australia, East Asia and Europe continue this work in diff erent ways, but the main idea is the same. Here, the main idea is designing and sustaining educational systems based on learning outcomes, student centered approaches, system evaluation and quality cycles rather than inputs. Studies carried out in parallel with developments in the world are made under European Higher Education Area/Bologna Process. Th e aim here is to have graduates who are world citizens open to change. In recent years, in parallel with the changes in the world, especially based on Bologna Process reforms, comprehensive studies such as National Qualifications Framework, ECTS credits, student exchange programs and quality assurance systems are carried out in Turkey. Challenges, problems and bureaucracy make diff icult to sustain these important studies. Create a cycle in order to ensure the sustainability of the quality of this work is the most important step. A university management and evaluation scheme is consisting of corporate figures such as student, academic staff , physical infrastructure and financial parameters, and process qualities for student achievement, scientific research and community share, and their results shaped by managerial and behavioral capability of the system. Goals, objectives and performance in activities of individuals, departments and faculty of the universities are gett ing more important to identify and evaluate in certain periods. Th is challenging work having high bureaucracy strains university management and other stakeholders, and increases resistance to the quality processes. Establishing systems to ensure the sustainable quality gains importance as understanding and implementing the change in the world. Operating these quality processes with a systematic approach based on web technologies will result in reduced work load, increased

  7. Approaching the Students to Achieve Creative Teaching —— A primary Research on Applied Writing%贴近学生 创新教学——应用写作课教学初探

    Institute of Scientific and Technical Information of China (English)

    钮中跃; 于梦


    Foreign languages, computer skills and applied writing abilities are regarded as the three basic skills in starting career. With the development of globalization, infomationization, urbanization, marketization and ecologicalization,there is more demand for the teaching of Applied Writing. This paper aims to help improve teaching concept and innovate teaching techniques of Applied Writing by discussing the following aspects: setting writing situation ,building a writing platform and motivating students' writing interest.%有人把"外语、电脑、应用写作"视为当代青年立身创业的"三大基本功"。伴随全球化、信息化、城镇化、市场化、生态化的进程,对应用写作的要求越来越高。本文从设置写作情境、搭建写作平台、激发写作兴趣着眼,就改进和创新应用写作课程教学理念与方法做了相应的尝试。

  8. Mesothelioma Applied Research Foundation (United States)

    ... Percentage Donations Tribute Wall Other Giving/Fundraising Opportunities Bitcoin Donation Form FAQs Speak with Mary Hesdorffer, Nurse ... Percentage Donations Tribute Wall Other Giving/Fundraising Opportunities Bitcoin Donation Form FAQs © 2017 Mesothelioma Applied Research Foundation, ...

  9. Applied eye tracking research

    NARCIS (Netherlands)

    Jarodzka, Halszka


    Jarodzka, H. (2010, 12 November). Applied eye tracking research. Presentation and Labtour for Vereniging Gewone Leden in oprichting (VGL i.o.), Heerlen, The Netherlands: Open University of the Netherlands.

  10. Computer and Applied Ethics


    越智, 貢


    With this essay I treat some problems raised by the new developments in science and technology, that is, those about Computer Ethics to show how and how far Applied Ethics differs from traditional ethics. I take up backgrounds on which Computer Ethics rests, particularly historical conditions of morality. Differences of conditions in time and space explain how Computer Ethics and Applied Ethics are not any traditional ethics in concrete cases. But I also investigate the normative rea...

  11. Approaching transdisciplinarity: some historical lines, foundations and applied principles to team work / Aproximações sobre a transdisciplinaridade: algumas linhas históricas, fundamentos e princípios aplicados ao trabalho de equipe

    Directory of Open Access Journals (Sweden)

    Isac Nikos Iribarry


    Full Text Available This article aims at presenting some conceptual and practical approaches on transdisciplinarity. At first, all the made approaches will be presented in an alterned way with the theorical presentation of themes related to transdisciplinarity. Some practical illustrations of those concepts will be presented as well. The concept of disciplinarity and its derivations – multidisciplinarity, pluridisciplinarity and transdisciplinarity – are examined in their differences, as well as in their consequences for establishing a relationship between different areas. Following that, some historical origins and foundations of transdisciplinarity will be presented. In the last part of this paper, the practical principles of team work in a case of transdisciplinarity will be discussed. Those principles are organized from the work carried out by the team work, the generation of new devices to foster familiarising of professionals from different areas, the readability and sharing of discourses, as well as horizontal decision making.

  12. A Regional Guidebook for Applying the Hydrogeomorphic Approach to Assessing Functions of Forested Wetlands in the Delta Region of Arkansas, Lower Mississippi River Alluvial Valley, Version 2.0 (United States)


    floodplain and the stream channel also are important determinants of flood flow interactions. The morphology of the stream channel and its floodplain...wetlands along environmental gradients. Wetlands 13: 65-74. __________. 1995. The hydrogeomorphic approach explained. National Wetlands Newsletter ... Newsletter , January/February, Environmental Law Institute, Washington, DC. ERDC/EL TR-11-12 155 Brinson, M. M., H. D. Bradshaw, and E. S. Kane. 1984

  13. Computing broadband accelerograms using kinematic rupture modeling; Generation d'accelerogrammes synthetiques large-bande par modelisation cinematique de la rupture sismique

    Energy Technology Data Exchange (ETDEWEB)

    Ruiz Paredes, J.A


    In order to make the broadband kinematic rupture modeling more realistic with respect to dynamic modeling, physical constraints are added to the rupture parameters. To improve the slip velocity function (SVF) modeling, an evolution of the k{sup -2} source model is proposed, which consists to decompose the slip as a sum of sub-events by band of k. This model yields to SVF close to the solution proposed by Kostrov for a crack, while preserving the spectral characteristics of the radiated wave field, i.e. a w{sup 2} model with spectral amplitudes at high frequency scaled to the coefficient of directivity C{sub d}. To better control the directivity effects, a composite source description is combined with a scaling law defining the extent of the nucleation area for each sub-event. The resulting model allows to reduce the apparent coefficient of directivity to a fraction of C{sub d}, as well as to reproduce the standard deviation of the new empirical attenuation relationships proposed for Japan. To make source models more realistic, a variable rupture velocity in agreement with the physics of the rupture must be considered. The followed approach that is based on an analytical relation between the fracture energy, the slip and the rupture velocity, leads to higher values of the peak ground acceleration in the vicinity of the fault. Finally, to better account for the interaction of the wave field with the geological medium, a semi-empirical methodology is developed combining a composite source model with empirical Green functions, and is applied to the Yamaguchi, M{sub w} 5.9 earthquake. The modeled synthetics reproduce satisfactorily well the observed main characteristics of ground motions. (author)

  14. Modeling and numerical analysis of non-equilibrium two-phase flows; Modelisation et analyse numerique des ecoulements diphasiques en desequilibre

    Energy Technology Data Exchange (ETDEWEB)

    Rascle, P.; El Amine, K. [Electricite de France (EDF), Direction des Etudes et Recherches, 92 - Clamart (France)


    We are interested in the numerical approximation of two-fluid models of nonequilibrium two-phase flows described by six balance equations. We introduce an original splitting technique of the system of equations. This technique is derived in a way such that single phase Riemann solvers may be used: moreover, it allows a straightforward extension to various and detailed exchange source terms. The properties of the fluids are first approached by state equations of ideal gas type and then extended to real fluids. For the construction of numerical schemes , the hyperbolicity of the full system is not necessary. When based on suitable kinetic unwind schemes, the algorithm can compute flow regimes evolving from mixture to single phase flows and vice versa. The whole scheme preserves the physical features of all the variables which remain in the set of physical states. Several stiff numerical tests, such as phase separation and phase transition are displayed in order to highlight the efficiency of the proposed method. The document is a PhD thesis divided in 6 chapters and two annexes. They are entitled: 1. - Introduction (in French), 2. - Two-phase flow, modelling and hyperbolicity (in French), 3. - A numerical method using upwind schemes for the resolution of two-phase flows without exchange terms (in English), 4. - A numerical scheme for one-phase flow of real fluids (in English), 5. - An upwind numerical for non-equilibrium two-phase flows (in English), 6. - The treatment of boundary conditions (in English), A.1. The Perthame scheme (in English) and A.2. The Roe scheme (in English). 136 refs. This document represents a PhD thesis in the speciality Applied Mathematics presented par Khalid El Amine to the Universite Paris 6.

  15. Marine and fluvial facies modelling at petroleum reservoir scale; Modelisation des heterogeneites lithologiques a l'echelle du reservoir petrolier en milieu marin et fluviatile

    Energy Technology Data Exchange (ETDEWEB)

    Leflon, B.


    When modelling a petroleum reservoir, well data are very useful to model properties at a sub-seismic scale. Petrophysical properties like porosity or permeability are linked to the rock-type. Two methods based on well data have been developed to model facies. The first one is used to model marine carbonates deposits. The geometry of sedimentary layers is modelled through a special parameterization of the reservoir similar to Wheeler space. The time parameter is defined along the well paths thanks to correlations. The layer thickness is then extrapolated between wells. A given relationship between facies and bathymetry of sedimentation makes it possible to compute bathymetry along the well paths. Bathymetry is then extrapolated from wells and a reference map using the concept of accommodation. The model created this way is stratigraphically consistent. Facies simulation can then be constrained by the computed bathymetry. The second method describes a novel approach to fluvial reservoirs modelling. The core of the method lies in the association of a fairway with the channels to be simulated. Fairways are positioned so that all data are taken in account; they can be stochastic if unknown or explicitly entered if identified on seismic data. A potential field is defined within the fairway. Specifying a transfer function to map this potential field to thickness results in generating a channel inside the fairway. A residual component is stochastically simulated and added to the potential field creating realistic channel geometries. Conditioning to well data is obtained by applying the inverse transfer function at the data location to derive thickness values that will constrain the simulation of residuals. (author)

  16. Applied anatomy of modified anterolateral approach for type C fractures of the distal femur%改良股前外侧入路治疗股骨远端C型骨折的应用解剖

    Institute of Scientific and Technical Information of China (English)

    骆松; 戴闽; 张斌; 戴江华; 聂涛; 邱平


    Objective To provide anatomic basis for treating type C fractures of the distal femur by the modified anterolateral approach of the thigh.Methods Main anterolateral muscles,ligaments were observed on 12 lower limbs of adult cadavers; the modified anterolateral approach was used,and the vessels and nerves related to the posterolateral approach were measured.Results The modified anterolateral approach could fully expose the distal femur without risk of injuring the important nerves and vessels.What's more,it did not affectthe iliotibial band and could attenuate the damage to the quadriceps femoris,which could cffectivelyprotectthe extensor mechanism of the knee joint.Conclusions The treatment of the fracture of the distal femur by the modified anterolateral approach is safe,less traumatic and and greater in is worth of further promotion.%目的 为改良股前外侧入路治疗股骨远端C型骨折提供解剖学基础.方法 福尔马林防腐成人下肢标本12例,解剖观察大腿下段前外侧的主要肌肉、韧带的分布;采用改良前外侧手术入路,测量该入路相关的神经、血管走行特点.结果 改良股前外侧入路可充分显露股骨远端,不损伤重要神经血管,不损伤髂胫束并减少了对股四头肌的损伤,有效地保护了伸膝装置.结论 改良股前外侧入路治疗股骨远端C型骨折具有安全,损伤较小,暴露充分等优点,有一定的推广价值.

  17. Applied chemical engineering thermodynamics

    CERN Document Server

    Tassios, Dimitrios P


    Applied Chemical Engineering Thermodynamics provides the undergraduate and graduate student of chemical engineering with the basic knowledge, the methodology and the references he needs to apply it in industrial practice. Thus, in addition to the classical topics of the laws of thermodynamics,pure component and mixture thermodynamic properties as well as phase and chemical equilibria the reader will find: - history of thermodynamics - energy conservation - internmolecular forces and molecular thermodynamics - cubic equations of state - statistical mechanics. A great number of calculated problems with solutions and an appendix with numerous tables of numbers of practical importance are extremely helpful for applied calculations. The computer programs on the included disk help the student to become familiar with the typical methods used in industry for volumetric and vapor-liquid equilibria calculations.


    Richmond, Stephen H


    The question of how to place psychoanalysis in relation to science has been debated since the beginning of psychoanalysis and continues to this day. The author argues that psychoanalysis is best viewed as a form of applied art (also termed applied aesthetics) in parallel to medicine as applied science. This postulate draws on a functional definition of modernity as involving the differentiation of the value spheres of science, art, and religion. The validity criteria for each of the value spheres are discussed. Freud is examined, drawing on Habermas, and seen to have erred by claiming that the psychoanalytic method is a form of science. Implications for clinical and metapsychological issues in psychoanalysis are discussed.

  19. Applied Literature for Healing,

    Directory of Open Access Journals (Sweden)

    Susanna Marie Anderson


    Full Text Available In this qualitative research study interviews conducted with elite participants serve to reveal the underlying elements that unite the richly diverse emerging field of Applied Literature. The basic interpretative qualitative method included a thematic analysis of data from the interviews yielding numerous common elements that were then distilled into key themes that elucidated the beneficial effects of engaging consciously with literature. These themes included developing a stronger sense of self in balance with an increasing connection with community; providing a safe container to engage challenging and potentially overwhelming issues from a stance of empowered action; and fostering a healing space for creativity. The findings provide grounds for uniting the work being done in a range of helping professions into a cohesive field of Applied Literature, which offers effective tools for healing, transformation and empowerment. Keywords: Applied Literature, Bibliotherapy, Poetry Therapy, Arts in Corrections, Arts in Medicine

  20. Applied mathematics made simple

    CERN Document Server

    Murphy, Patrick


    Applied Mathematics: Made Simple provides an elementary study of the three main branches of classical applied mathematics: statics, hydrostatics, and dynamics. The book begins with discussion of the concepts of mechanics, parallel forces and rigid bodies, kinematics, motion with uniform acceleration in a straight line, and Newton's law of motion. Separate chapters cover vector algebra and coplanar motion, relative motion, projectiles, friction, and rigid bodies in equilibrium under the action of coplanar forces. The final chapters deal with machines and hydrostatics. The standard and conte

  1. Retransmission Steganography Applied

    CERN Document Server

    Mazurczyk, Wojciech; Szczypiorski, Krzysztof


    This paper presents experimental results of the implementation of network steganography method called RSTEG (Retransmission Steganography). The main idea of RSTEG is to not acknowledge a successfully received packet to intentionally invoke retransmission. The retransmitted packet carries a steganogram instead of user data in the payload field. RSTEG can be applied to many network protocols that utilize retransmissions. We present experimental results for RSTEG applied to TCP (Transmission Control Protocol) as TCP is the most popular network protocol which ensures reliable data transfer. The main aim of the performed experiments was to estimate RSTEG steganographic bandwidth and detectability by observing its influence on the network retransmission level.

  2. On applying cognitive psychology. (United States)

    Baddeley, Alan


    Recent attempts to assess the practical impact of scientific research prompted my own reflections on over 40 years worth of combining basic and applied cognitive psychology. Examples are drawn principally from the study of memory disorders, but also include applications to the assessment of attention, reading, and intelligence. The most striking conclusion concerns the many years it typically takes to go from an initial study, to the final practical outcome. Although the complexity and sheer timescale involved make external evaluation problematic, the combination of practical satisfaction and theoretical stimulation make the attempt to combine basic and applied research very rewarding.

  3. Applied Electromagnetism and Materials

    CERN Document Server

    Moliton, André


    Applied Electromagnetism and Materials picks up where the author's Basic Electromagnetism and Materials left off by presenting practical and relevant technological information about electromagnetic material properties and their applications. This book is aimed at senior undergraduate and graduate students as well as researchers in materials science and is the product of many years of teaching basic and applied electromagnetism. Topics range from the spectroscopy and characterization of dielectrics and semiconductors, to non-linear effects and electromagnetic cavities, to ion-beam applications in materials science.

  4. Applied Astronomy: Asteroid Prospecting (United States)

    Elvis, M.


    In the age of asteroid mining the ability to find promising ore-bearing bodies will be valuable. This will give rise to a new discipline- "Applied Astronomy". Just as most geologists work in industry, not in academia, the same will be true of astronomers. Just how rare or common ore-rich asteroids are likely to be, and the skills needed to assay their value, are discussed here, with an emphasis on remote - telescopic - methods. Also considered are the resources needed to conduct extensive surveys of asteroids for prospecting purposes, and the cost and timescale involved. The longer-term need for applied astronomers is also covered.

  5. Discussion on Feasibility of Applying Market Approach to Enterprise Value Evaluation%我国企业价值评估中应用市场法的可行性探讨

    Institute of Scientific and Technical Information of China (English)



    With the rise of the knowledge economy and the development of economic globalization, the business valuation case in economic market is also growing. This paper analyzes the problems when business valuation being in line with international market, proposes to use market approach to assess value at present, further analyzes the feasibility of using financial markets to evaluate enterprise value by market, and thinks that China's market conditions have realized the condition that using market approach to assess the enterprise value.%随着知识经济的兴起和经济全球化的发展,经济市场中的企业价值评估案例也日益增加.本文分析了企业价值评估的业务在与国际市场接轨时遇到的问题提出了目前应该更多地运用市场法来评估企业价值,并进一步分析了现在的金融市场对市场法评估企业价值的可行性,认为我国的市场条件具备了应用市场法评估企业价值的条件.

  6. 项目教学法在机械装配与维修专业中应用的研究%Applied Investigation of Project Teaching Approach in Speciality of Mechanical Assembly and Maintenance

    Institute of Scientific and Technical Information of China (English)



    项目教学法是以建构主义理论为基础,通过选取"项目"来创设"情景",通过"协作学习"的方式开展学习,通过完成"项目"来达到"意义建构",是一种比较有效的教学方法.本文对在机械装配与维修专业中实施项目教学法进行了研究,并对整个教学方案进行了设计,为下一步实施项目教学奠定了理论基础.%Project teaching approach which is based on the theory of constructivism is a highly effective teaching method. The scenes created by choosing some projects, the learning through collaborative learning and the meaning constructions are achieved by accomplishing the projects. The study about project approach in speciality of mechanical assembly and maintenance was conducted, the teaching programs were designed for further implementation project teaching too.

  7. Africa and Applied Linguistics. (United States)

    Makoni, Sinfree, Ed.; Meinhof, Ulrike H., Ed.


    This collection of articles includes: "Introducing Applied Linguistics in Africa" (Sinfree Makoni and Ulrike H. Meinhof); "Language Ideology and Politics: A Critical Appraisal of French as Second Official Language in Nigeria" (Tope Omoniyi); "The Democratisation of Indigenous Languages: The Case of Malawi" (Themba…

  8. Applying Literature to ELT

    Institute of Scientific and Technical Information of China (English)



    Literature is no longer a frightening word to English language learner. Interactive teaching methods and attractive activities can help motivating Chinese university English learners. This essay will first elaborate the reasons to use literature in ELT ( English Language Teaching) class and how to apply literature to ELT class.

  9. Essays on Applied Microeconomics (United States)

    Mejia Mantilla, Carolina


    Each chapter of this dissertation studies a different question within the field of Applied Microeconomics. The first chapter examines the mid- and long-term effects of the 1998 Asian Crisis on the educational attainment of Indonesian children ages 6 to 18, at the time of the crisis. The effects are identified as deviations from a linear trend for…

  10. Applying Mixed Methods Research at the Synthesis Level: An Overview (United States)

    Heyvaert, Mieke; Maes, Bea; Onghena, Patrick


    Historically, qualitative and quantitative approaches have been applied relatively separately in synthesizing qualitative and quantitative evidence, respectively, in several research domains. However, mixed methods approaches are becoming increasingly popular nowadays, and practices of combining qualitative and quantitative research components at…

  11. Applied Anatomy of A New Approach of Endoscopic Technique in Thyroid Gland Surgery%甲状腺手术内镜新入路的应用解剖学基础

    Institute of Scientific and Technical Information of China (English)

    刘鸿; 谢拥军; 徐义全; 李超; 刘兴国


    目的 通过对气道联合舌下的解剖通路、层次及毗邻结构的实验研究,为经此入路完全内镜下行甲状腺切除术的安全可行性提供解剖学依据.方法 在5例(成都医学院人体解剖实验室受捐)结构完整经防腐固定的头颈部成年标本上参照气道联合舌下入路行口腔底、咽部及颈前部解剖,确定经此人路的解剖路径及层次.15例结构完整未经防腐固定的新鲜头颈部成年标本,运用丙烯腈-丁二烯-苯乙烯共聚物丁酮溶液行左右颈总动脉预灌注,分别作血管铸型、计算机断层扫描技术及薄层冰冻铣切等方法,对甲状腺及毗邻术区的解剖结构作定性和定量研究,并运用Autodesk3ds Max 2010(32位)对喉部动脉进行三维重建.在5例结构完整未经防腐固定的新鲜头颈部成年标本上模拟经气道联合舌下解剖路径完全内镜下甲状腺切除术.结果 经舌下的内镜通道为自舌下正中区,依次穿行颏舌骨肌、下颌舌骨缝、颏下三角区至颈阔肌深面,经封套筋膜、舌骨体前缘、舌骨下肌群至甲状腺术区.经气道的操作通道为自固有口腔,依次经咽峡、会厌下缘、喉咽、喉中间腔,移行至气管颈部,在气管软骨环前壁作矢状切口至甲状腺术区.结论 完全内镜气道联合舌下入路行甲状腺切除术在解剖上有其安全操作层次和范围可循,在临床上对甲状腺外科领域具有参考价值.%Objective To explore the feasibility and safety of transtracheal assisted sublingual approach to totally endoscopic thyroidectomy by studying the anatomical approach and adjacent structures. Methods A total of 5 embalmed adult cadavers from Chengdu Medical College were dissected layer by layer in the cervical region, pharyngeal region, and mandible region, according to transtracheal assisted sublingual approach that was verified from the anatomical approach and planes. A total of 15 embalmed adult cadavers were dissected

  12. 13th European Conference on Applied Superconductivity

    CERN Document Server


    EUCAS is a worldwide forum for scientists and engineers, and provides an ideal platform to share knowledge and the most recent advances in all areas of applied superconductivity: from large-scale applications to miniature electronics devices, with a traditional focus on advanced materials and conductors. The broad scope is at the same time a challenge and an opportunity to foster novel, inter-disciplinary approaches and promote cross-fertilization among the various fields of applied superconductivity.

  13. Establishing ecological reference conditions and tracking post-application effectiveness of lanthanum-saturated bentonite clay (Phoslock®) for reducing phosphorus in aquatic systems: an applied paleolimnological approach. (United States)

    Moos, M T; Taffs, K H; Longstaff, B J; Ginn, B K


    Innovative management strategies for nutrient enrichment of freshwater are important in the face of this increasing global problem, however many strategies are not assessed over long enough time periods to establish effectiveness. Paleolimnological techniques using diatoms as biological indicators were utilized to establish ecological reference conditions, environmental variation, and the effectiveness of lanthanum-saturated bentonite clay (brand name: Phoslock(®)) applied to reduce water column phosphorus (P) concentrations in four waterbodies in Ontario, Canada, and eastern Australia. In sediment cores from the two Canadian sites, there were short-lived changes to diatom assemblages, relative to inferred background conditions, and a temporary reduction in both measured and diatom-inferred total phosphorus (TP) before returning to pre-application conditions (particularly in the urban stormwater management pond which has a high flushing rate and responds rapidly to precipitation and surface run-off). The two Australian sites (a sewage treatment pond and a shallow recreational lake), recorded no reduction in diatom-inferred TP. Based on our pre-application environmental reconstruction, changes to the diatom assemblages and diatom-inferred TP appeared to be driven by larger, climatic factors. While laboratory tests involving this product showed sharp reductions in water column TP, management strategies require detailed information on pre-application environmental conditions and variations in order to accurately assess the effectiveness of new technologies for lake management.

  14. The applied anatomy and clinical application of the transoral approach with mandibulotomy and mandibuloglossotomy%经口咽下颌骨劈开扩大入路的应用解剖及临床应用

    Institute of Scientific and Technical Information of China (English)

    何玥; 尹庆水; 夏虹; 艾福志; 王智运


    目的 为经口咽下颌骨劈开扩大入路提供解剖学依据.方法 6例新鲜成人头颈部标本,以模拟手术方式,依次行经口下颌骨劈开(保留舌体)和经口下颌骨、舌体劈开扩大入路解剖至颈髓,依次测量并记录两种入路的显露范围,探查性操作范围及重建性操作范同,测量双侧椎动脉相关解剖数据.结果 两种扩大入路的显露角度分别为(63.67±3.50)°和(74.14± 1.47)°.最大探查性操作范围分别为斜坡下1/3→C5上终板和斜坡下1/3→C6上终板,最大重建性操作范围分别为C2下1/2→C5上终板和C2下1/2→C6上终板.椎动脉距中线C2/3为(16.88±0.75)mm;C3/4为(16.48± 1.47)mm,C4/5为(16.30± 1.09)mm;距门齿垂直深度C2/3为(96.44±3.59)mm;C3/4为(97.94±4.51)mm,C4/5为(99.83±4.77)mm. 结论 经口咽下颌骨劈开扩大入路是处理张口受限和颈脊髓腹侧长节段病变的安全、有效的入路,需据手术范围确定是否劈开舌体.%Objective This study was designed to investigate the anatomic foundation for the transoral approach with mandibulutomy and mandibuloglossotomy. Methods Transoral approach with mandubulutomy and mandibuloglossotomy were simulated in 6 fresh cadavers to cervical spinal cord; the cephalic and caudal limits of exposure and the distances between the vertebral artery (VA) of each side to the midline and the vertical depth between the VA of each side to the fore-teeth of the two approaches were measured. Furthermore, the exploratory operational range and reconstructive operational range were described. Results The exposure angle of mandibulotomy and mandibuloglossotomy were 63.67° ±3.50° and 74.14°± 1.47°, respectively.The widest EOR of mandibulotomy and mandibuloglossotomy were the lower third of the clivus to the upper edge of C5 and the lower third of the clivus to the upper edge of C6, respectively.The widest ROR of mandibulotomy and mandibuloglossotomy were the lower half of axis to the upper edge of

  15. 喉返神经在颈椎前入路手术中的应用解剖学研究%Applied Anatomy Research of Recurrent Laryngeal Nerve in Anterior Cervical Approach Operation

    Institute of Scientific and Technical Information of China (English)

    骆明炎; 范伟杰; 谢兴国; 吴亚琼; 唐芳; 周可为


    Objective To provide anatomical basis for anterior approach to cervical spine surgery protecting the re-current laryngeal nerve. Methods Forty formalin-fixed adult cadavers (23 male/ 17female) were dissected bilaterally to expose the path of the recurrent laryngeal nerve ( RLN) . The starting point,the first branch and the entering tracheoesopha-geal groove point were observed corresponding with vertebral body level. Results The right RLN looped around the sub-clavian artery at the level of T2. It crossed the prevertebral fascia from the carotid sheath medial border at T1 level,entered the tracheoesophageal groove at C7-T1 level and entered the larynx at C6. The left RLN looped around the aortic arch at T4 level,entered the tracheoesophageal groove at T2 level and entered the larynx at C6 level. The RLN traveled superiorly, slightly anterior to the tracheoesophageal groove and its diameter tapered. The first branch diameter minimum value is 0. 02mm. The starting point of RLN diameter maximum value is 4. 76mm. Conclusions The left RLN anatomical structure is relatively more constant than the right side. The left or right anterior approach to cervical spine surgery at or superior to C7 level is safe,but inferior to C7 level the left anterior approach is better. Mastering the anatomical characteristics of RLN is important to reduce the iatrogenic injury.%目的:为临床颈椎前入路手术保护喉返神经提供解剖学依据。方法取成人尸体标本40具(男23,女17),共80侧。在颈动脉鞘与气管食管间的颈根部找到喉返神经,测量各侧喉返神经起点、入气管食管沟点和入喉第一分支点各部横径及其与颈椎对应的位置关系。结果右侧喉返神经在T2椎体水平绕右锁骨下动脉上行,T1椎体水平自颈动脉鞘内侧缘穿出椎前筋膜,C7T1椎体水平向内、上、前进入气管食管沟;左侧喉返神经在T4椎体水平绕主动脉弓上行,在T2椎体水平进入气管食管沟,在沟内行

  16. Applied anatomy of the posterior wall of sphenoid sinus during endoscopic extended transsphenoidal approach%内镜下扩大经蝶术中蝶窦后壁的应用解剖

    Institute of Scientific and Technical Information of China (English)

    刘环海; 廖建春; 范静平; 吴建; 赵舒薇; 党瑞山; 胡国汉; 王君玉; 彭浒


    Objective To provide anatomic data for accurately locating the important structures of sellar area and preventing injury during endoscopic extended transsphenoidal approach to the sellar area. Methods The extended transsphenoidal approach was employed in twenty cadavers via endoscope, and the posterior wall of sphenoid sinus was divided into different parts for localizing sella turcica, carotid protuberance and optic canal. Important structures were observed and measured under microscope. Results The posterior wall of sphenoid sinus was divided into five parts according to the four lines along the two sides of the two carotid protuberances. The depths of the sella turcica in the tuberculum sellae, anterior wall of sella turcica and sellar floor were (2. 20±0. 19 [0. 63-6.90]) mm, (0. 71±0.06 [0.36-2. 78]) mm, and (0. 94±0. 18 [0. 23-2.81]) mm, respectively. The transverse diameter, sagittal diameter and coronal diameter of pituitary gland were (14.72±1.07 [10. 92-18. 38]) mm, (10. 13±0. 92[9.37-12. 51]) mm and (5.13±0.74 (2.37-7.91]) mm, respectively. Conclusion The five parts of the posterior wall of sphenoid sinus in this study can facilitate the localization of important structures in the sellar area during the extended transsphenoidal approach to sellar area via endoscope, so as to prevent iatrogenic injury of vital structures in the sellar area.%目的 为鼻内镜下扩大经蝶蝶鞍区手术中准确定位及避免损伤鞍区重要解剖结构提供解剖学参数.方法 在鼻内镜下对20例头颅标本解剖,并对蝶窦后壁进行分区,准确定位蝶鞍、颈内动脉隆凸、视神经管.显微镜下观察、测量相关解剖结构.结果 沿颈内动脉隆凸两侧缘分别画2条直线,4条直线将蝶窦后壁分成5个区域.测量了蝶鞍不同部位的厚度:鞍结节[2.20±0.19(0.63~6.90)] mm,鞍前壁[0.71±0.06 (0.36~2.78)] mm;鞍底[0.94±0.18 (0.23~2.81)] mm.垂体的横径为[14.72±1.07(10.92~18.38)] mm

  17. Applied longitudinal analysis

    CERN Document Server

    Fitzmaurice, Garrett M; Ware, James H


    Praise for the First Edition "". . . [this book] should be on the shelf of everyone interested in . . . longitudinal data analysis.""-Journal of the American Statistical Association   Features newly developed topics and applications of the analysis of longitudinal data Applied Longitudinal Analysis, Second Edition presents modern methods for analyzing data from longitudinal studies and now features the latest state-of-the-art techniques. The book emphasizes practical, rather than theoretical, aspects of methods for the analysis of diverse types of lo

  18. Applied statistics for economists

    CERN Document Server

    Lewis, Margaret


    This book is an undergraduate text that introduces students to commonly-used statistical methods in economics. Using examples based on contemporary economic issues and readily-available data, it not only explains the mechanics of the various methods, it also guides students to connect statistical results to detailed economic interpretations. Because the goal is for students to be able to apply the statistical methods presented, online sources for economic data and directions for performing each task in Excel are also included.

  19. Applied Economics in Teaching

    Institute of Scientific and Technical Information of China (English)



    This paper explains some plain phenomena in teaching and class management with an economic view. Some basic economic principles mentioned therein are: everything has its opportunity cost; the marginal utility of consumption of any kind is diminishing; Game theory is everywhere. By applying the economic theories to teaching, it is of great help for teachers to understand the students' behavior and thus improve the teaching effectiveness and efficiency.

  20. Methods of applied mathematics

    CERN Document Server

    Hildebrand, Francis B


    This invaluable book offers engineers and physicists working knowledge of a number of mathematical facts and techniques not commonly treated in courses in advanced calculus, but nevertheless extremely useful when applied to typical problems in many different fields. It deals principally with linear algebraic equations, quadratic and Hermitian forms, operations with vectors and matrices, the calculus of variations, and the formulations and theory of linear integral equations. Annotated problems and exercises accompany each chapter.

  1. Aproximações sobre a transdisciplinaridade: algumas linhas históricas, fundamentos e princípios aplicados ao trabalho de equipe Approaching transdisciplinarity: some historical lines, foundations and applied principles to team work

    Directory of Open Access Journals (Sweden)

    Isac Nikos Iribarry


    Full Text Available O objetivo deste artigo é o de apresentar algumas aproximações conceituais e práticas sobre o tema da transdisciplinaridade. Em um primeiro momento, as aproximações realizadas serão alternadas pela exposição teórica dos temas relacionados à transdisciplinaridade e por algumas ilustrações práticas dos conceitos. O conceito de disciplina e suas derivações - multidisciplinaridade, pluridisciplinaridade, interdisciplinaridade e transdisciplinaridade - serão examinados em suas diferenças e conseqüências para o estabelecimento de relações entre diferentes disciplinas. Em seguida, serão apresentadas algumas origens históricas e alguns fundamentos da transdisciplinaridade. Na etapa final do trabalho, serão examinados os princípios práticos do trabalho de equipe em uma situação de transdisciplinaridade. Tais princípios estão organizados a partir do trabalho em equipe, da geração de novos dispositivos, da familiarização dos profissionais com cada área diferente da sua, da legibilidade e compartilhamento dos discursos e da tomada de decisão horizontal.This article aims at presenting some conceptual and practical approaches on transdisciplinarity. At first, all the made approaches will be presented in an alterned way with the theorical presentation of themes related to transdisciplinarity. Some practical illustrations of those concepts will be presented as well. The concept of disciplinarity and its derivations - multidisciplinarity, pluridisciplinarity and transdisciplinarity - are examined in their differences, as well as in their consequences for establishing a relationship between different areas. Following that, some historical origins and foundations of transdisciplinarity will be presented. In the last part of this paper, the practical principles of team work in a case of transdisciplinarity will be discussed. Those principles are organized from the work carried out by the team work, the generation of new devices

  2. Modeling of turbulent flows in porous media and at the interface with a free fluid medium; Modelisation des ecoulements turbulents dans les milieux poreux et a l'interface avec un milieu libre

    Energy Technology Data Exchange (ETDEWEB)

    Chandesris, M


    This work deals with the numerical simulation of turbulent flows in the whole nuclear reactor core, using multi-scale approaches. First, a macroscopic turbulence model is built, based on a porous media approach, to describe the flow in the fuel assemblies part of the nuclear core. Then, we study the jump conditions that have to be applied at a free fluid/porous interface. A thorough analytical study is carried out for laminar flows. This study allows to answer some fundamental questions about the physical meaning of the jump conditions, the values of the jump parameters and the location of the interface. Using these results, jump conditions for turbulent flows are proposed. The model is then applied to the simulation of a turbulent flow in a simplified model of a reactor core. (author)

  3. Analyzing the proximity to cover in a landscape of fear: a new approach applied to fine-scale habitat use by rabbits facing feral cat predation on Kerguelen archipelago

    Directory of Open Access Journals (Sweden)

    Pierrick Blanchard


    Full Text Available Although proximity to cover has been routinely considered as an explanatory variable in studies investigating prey behavioral adjustments to predation pressure, the way it shapes risk perception still remains equivocal. This paradox arises from both the ambivalent nature of cover as potentially both obstructive and protective, making its impact on risk perception complex and context-dependent, and from the choice of the proxy used to measure proximity to cover in the field, which leads to an incomplete picture of the landscape of fear experienced by the prey. Here, we study a simple predator-prey-habitat system, i.e., rabbits Oryctolagus cuniculus facing feral cat Felis catus predation on Kerguelen archipelago. We assess how cover shapes risk perception in prey and develop an easily implementable field method to improve the estimation of proximity to cover. In contrast to protocols considering the “distance to nearest cover”, we focus on the overall “area to cover”. We show that fine-scale habitat use by rabbits is clearly related to our measure, in accordance with our hypothesis of higher risk in patches with smaller area to cover in this predator-prey-habitat system. In contrast, classical measures of proximity to cover are not retained in the best predictive models of habitat use. The use of this new approach, together with a more in-depth consideration of contrasting properties of cover, could help to better understand the role of this complex yet decisive parameter for predator-prey ecology.

  4. An Investigation of the Communicative Approach Teaching in Primary English Textbooks in Hong Kong and Malaysia: A Search into Communicative Language Teaching (CLT Textbooks, And How CLT is Applied in Textbooks

    Directory of Open Access Journals (Sweden)

    Charles Ko


    Full Text Available In the present research, it will be shown how grammar activities in textbooks still retain the structural method of teaching grammar. The results found by previous scholars’ research will be covered, and illustrated by excerpts of textbooks, including comparison of Hong Kong and Malaysian textbooks. Communicative Language Teaching (CLT materialized in the West in the 1960s, and has extended to the Eastern countries over the last 20 years (Chung, 2005: 33. Since the introduction of CLT, many English textbooks have been published to incorporate communicative activities, authentic material and personalized contexts, however, most of the learning and teaching of grammar in textbooks do not fully reflect CLT principles (ibid.. The paper is written to show concerns over textbook designing issues and hence provide recommendations in changing the design of the modern English language textbooks. In the end of the paper, this research will suggest methods of designing more communicative grammar activities in English language textbooks for future textbook designers having guidelines in compiling the CLT English language textbooks. Besides, some approaches of communicative teaching with the CLT textbooks will be recommended to the pre- and in-service English language teachers in order to lead them to the current trend of CLT.

  5. Software Engineering applied to Manufacturing Problems

    Directory of Open Access Journals (Sweden)

    Jorge A. Ruiz-Vanoye


    Full Text Available Optimization approaches have traditionally been viewed as tools for solving manufacturing problems, the optimization approach is not suitable for many problems arising in modern manufacturing systems due to their complexity and involvement of qualitative factors. In this paper we use a tool of software engineering applied to manufacturing problems. We use the Heuristics Lab software to determine and analyze the solution obtained for Manufacturing Problems.

  6. Emotional Value of Applied Textiles

    DEFF Research Database (Denmark)

    Bang, Anne Louise


    The present PhD thesis is conducted as an Industrial PhD project in collaboration with the Danish company Gabriel A/S (Gabriel), which designs and produces furniture textiles and ‘related products’ for manufacturers of furniture. A ‘related textile product’ is e.g. processing of piece goods...... at Gabriel face while trying to implement an innovative and process-oriented business strategy. The focal point has been the section of the strategy which aims at developing Blue Ocean products, which have a functional and an emotional value for the user. The thesis examines and explores emotional value...... (procedures of user and stakeholder involvement). In the course of the thesis I explain and elaborate on four themes each of which contributes to the outcome of the project. 1) Creating a frame of reference for the textile design process and a systematic approach to applied textiles. In chapter three I...

  7. Effect analysis of applying solution-focused approach in health education for IVF-ET patients%聚焦解决模式在IVF-ET患者健康教育中应用的效果评价

    Institute of Scientific and Technical Information of China (English)



    目的:探讨聚焦解决模式的健康教育改善体外受精-胚胎移植术(IVF-ET)患者焦虑抑郁状况和社会支持水平的效果。方法120例IVF-ET患者分为实验组和对照组,每组60例。实验组患者采用聚焦解决模式5个步骤进行健康教育,对照组患者采用常规的健康教育指导。对两组患者分别在患者降调前、移植术后采用汗密尔顿焦虑量表(HAMA)、汗密尔顿抑郁量表(HAMD)和社会支持评定量表(SSRS)进行焦虑、抑郁状况及社会支持利用度的评价。结果移植术后两组患者的HAMA、HAMD和SSRS均较自身降调前有明显改善,但实验组改善程度更加显著,移植术后实验组的HAMA、HAMD和SSRS评分水平显著优于同期对照组水平(P<0.05)。结论聚焦解决模式的健康教育指导对IVF-ET患者焦虑抑郁症状及社会支持利用度有明显的改善效果,显著减轻了患者的焦虑、抑郁症状,提高了社会支持利用度,能够满足患者的健康教育需求,激发患者主动配合治疗的积极性,增加患者治疗的信心,改善患者的情绪,提高患者的应对能力和生活质量。%Objective To explore the effect of the health education through solution-focused approach in improving anxiety and depression states and social support level of in vitro fertilization and embryo transplantation (IVF-ET) patients. Methods A total of 120 IVF-ET patients were divided into experimental group and control group, with 60 cases in each group. The experimental group was given health education through solution-focused approach in 5 steps, while the control group received guidance of conventional health education. Hamilton anxiety scale (HAMA), Hamilton depression scale (HAMD) and social support rating scale (SSRS) were respectively used to evaluate the patients’anxiety and depression states and the utilization degree of social support in the two groups before down-regulation and after transplantation

  8. Applied data mining

    CERN Document Server

    Xu, Guandong


    Data mining has witnessed substantial advances in recent decades. New research questions and practical challenges have arisen from emerging areas and applications within the various fields closely related to human daily life, e.g. social media and social networking. This book aims to bridge the gap between traditional data mining and the latest advances in newly emerging information services. It explores the extension of well-studied algorithms and approaches into these new research arenas.

  9. Applied ALARA techniques

    Energy Technology Data Exchange (ETDEWEB)

    Waggoner, L.O.


    The presentation focuses on some of the time-proven and new technologies being used to accomplish radiological work. These techniques can be applied at nuclear facilities to reduce radiation doses and protect the environment. The last reactor plants and processing facilities were shutdown and Hanford was given a new mission to put the facilities in a safe condition, decontaminate, and prepare them for decommissioning. The skills that were necessary to operate these facilities were different than the skills needed today to clean up Hanford. Workers were not familiar with many of the tools, equipment, and materials needed to accomplish:the new mission, which includes clean up of contaminated areas in and around all the facilities, recovery of reactor fuel from spent fuel pools, and the removal of millions of gallons of highly radioactive waste from 177 underground tanks. In addition, this work has to be done with a reduced number of workers and a smaller budget. At Hanford, facilities contain a myriad of radioactive isotopes that are 2048 located inside plant systems, underground tanks, and the soil. As cleanup work at Hanford began, it became obvious early that in order to get workers to apply ALARA and use hew tools and equipment to accomplish the radiological work it was necessary to plan the work in advance and get radiological control and/or ALARA committee personnel involved early in the planning process. Emphasis was placed on applying,ALARA techniques to reduce dose, limit contamination spread and minimize the amount of radioactive waste generated. Progress on the cleanup has,b6en steady and Hanford workers have learned to use different types of engineered controls and ALARA techniques to perform radiological work. The purpose of this presentation is to share the lessons learned on how Hanford is accomplishing radiological work.

  10. Applied linear regression

    CERN Document Server

    Weisberg, Sanford


    Master linear regression techniques with a new edition of a classic text Reviews of the Second Edition: ""I found it enjoyable reading and so full of interesting material that even the well-informed reader will probably find something new . . . a necessity for all of those who do linear regression."" -Technometrics, February 1987 ""Overall, I feel that the book is a valuable addition to the now considerable list of texts on applied linear regression. It should be a strong contender as the leading text for a first serious course in regression analysis."" -American Scientist, May-June 1987

  11. Applying Popper's Probability

    CERN Document Server

    Whiting, Alan B


    Professor Sir Karl Popper (1902-1994) was one of the most influential philosophers of science of the twentieth century, best known for his doctrine of falsifiability. His axiomatic formulation of probability, however, is unknown to current scientists, though it is championed by several current philosophers of science as superior to the familiar version. Applying his system to problems identified by himself and his supporters, it is shown that it does not have some features he intended and does not solve the problems they have identified.

  12. Applied energy an introduction

    CERN Document Server

    Abdullah, Mohammad Omar


    Introduction to Applied EnergyGeneral IntroductionEnergy and Power BasicsEnergy EquationEnergy Generation SystemsEnergy Storage and MethodsEnergy Efficiencies and LossesEnergy industry and Energy Applications in Small -Medium Enterprises (SME) industriesEnergy IndustryEnergy-Intensive industryEnergy Applications in SME Energy industriesEnergy Sources and SupplyEnergy SourcesEnergy Supply and Energy DemandEnergy Flow Visualization and Sankey DiagramEnergy Management and AnalysisEnergy AuditsEnergy Use and Fuel Consumption StudyEnergy Life-Cycle AnalysisEnergy and EnvironmentEnergy Pollutants, S

  13. Applied linear regression

    CERN Document Server

    Weisberg, Sanford


    Praise for the Third Edition ""...this is an excellent book which could easily be used as a course text...""-International Statistical Institute The Fourth Edition of Applied Linear Regression provides a thorough update of the basic theory and methodology of linear regression modeling. Demonstrating the practical applications of linear regression analysis techniques, the Fourth Edition uses interesting, real-world exercises and examples. Stressing central concepts such as model building, understanding parameters, assessing fit and reliability, and drawing conclusions, the new edition illus

  14. Applied impulsive mathematical models

    CERN Document Server

    Stamova, Ivanka


    Using the theory of impulsive differential equations, this book focuses on mathematical models which reflect current research in biology, population dynamics, neural networks and economics. The authors provide the basic background from the fundamental theory and give a systematic exposition of recent results related to the qualitative analysis of impulsive mathematical models. Consisting of six chapters, the book presents many applicable techniques, making them available in a single source easily accessible to researchers interested in mathematical models and their applications. Serving as a valuable reference, this text is addressed to a wide audience of professionals, including mathematicians, applied researchers and practitioners.

  15. Applied Semantic Web Technologies

    CERN Document Server

    Sugumaran, Vijayan


    The rapid advancement of semantic web technologies, along with the fact that they are at various levels of maturity, has left many practitioners confused about the current state of these technologies. Focusing on the most mature technologies, Applied Semantic Web Technologies integrates theory with case studies to illustrate the history, current state, and future direction of the semantic web. It maintains an emphasis on real-world applications and examines the technical and practical issues related to the use of semantic technologies in intelligent information management. The book starts with

  16. Applied Chaos Control (United States)

    Spano, Mark


    The publication by Ott, Grebogi and Yorke(E. Ott, C. Grebogi and J. A. Yorke, Phys. Rev. Lett. 64, 1196 (1990).) of their theory of chaos control in 1990 led to an explosion of experimental work applying their theory to mechanical systems and electronic circuits, lasers and chemical reactors, and heart and brain tissue, to name only a few. In this talk the basics of chaos control as implemented in a simple mechanical system will be described, as well as extensions of the method to biological applications. Finally, current advances in the field, including the maintenance of chaos and the control of high dimensional chaos, will be discussed.

  17. Applied complex variables

    CERN Document Server

    Dettman, John W


    Analytic function theory is a traditional subject going back to Cauchy and Riemann in the 19th century. Once the exclusive province of advanced mathematics students, its applications have proven vital to today's physicists and engineers. In this highly regarded work, Professor John W. Dettman offers a clear, well-organized overview of the subject and various applications - making the often-perplexing study of analytic functions of complex variables more accessible to a wider audience. The first half of Applied Complex Variables, designed for sequential study, is a step-by-step treatment of fun

  18. Applied logistic regression

    CERN Document Server

    Hosmer, David W; Sturdivant, Rodney X


     A new edition of the definitive guide to logistic regression modeling for health science and other applications This thoroughly expanded Third Edition provides an easily accessible introduction to the logistic regression (LR) model and highlights the power of this model by examining the relationship between a dichotomous outcome and a set of covariables. Applied Logistic Regression, Third Edition emphasizes applications in the health sciences and handpicks topics that best suit the use of modern statistical software. The book provides readers with state-of-

  19. Workshop applied antineutrino physics 2007

    Energy Technology Data Exchange (ETDEWEB)

    Akiri, T.; Andrieu, B.; Anjos, J.; Argyriades, J.; Barouch, G.; Bernstein, A.; Bersillon, O.; Besida, O.; Bowden, N.; Cabrera, A.; Calmet, D.; Collar, J.; Cribier, M.; Kerret, H. de; Meijer, R. de; Dudziak, F.; Enomoto, S.; Fallot, M.; Fioni, G.; Fiorentini, G.; Gale, Ph.; Georgadze, A.; Giot, L.; Gonin, M.; Guillon, B.; Henson, C.; Jonkmans, G.; Kanamaru, S.; Kawasaki, T.; Kornoukhov, V.; Lasserre, Th.; Learned, J.G.; Lefebvre, J.; Letourneau, A.; Lhillier, D.; Lindner, M.; Lund, J.; Mantovani, F.; Mcdonough, B.; Mention, G.; Monteith, A.; Motta, D.; Mueller, Th.; Oberauer, L.; Obolensky, M.; Odrzywolek, A.; Petcov, S.; Porta, A.; Queval, R.; Reinhold, B.; Reyna, D.; Ridikas, D.; Sadler, L.; Schoenert, St.; Sida, J.L.; Sinev, V.; Suekane, F.; Suvorov, Y.; Svoboda, R.; Tang, A.; Tolich, N.; Tolich, K.; Vanka, S.; Vignaud, D.; Volpe, Ch.; Wong, H


    The 'Applied Antineutrino Physics 2007' workshop is the fourth international meeting devoted to the opening of the neutrino physics to more applied fields, such as geophysics and geochemistry, nuclear industry, as well as the nonproliferation. This meeting highlights the world efforts already engaged to exploit the single characteristics of the neutrinos for the control of the production of plutonium in the civil nuclear power reactor. The potential industrial application of the measurement of the thermal power of the nuclear plants by the neutrinos is also approached. earth neutrinos were for the first time highlighted in 2002 by the KamLAND experiment. Several international efforts are currently underway to use earth neutrinos to reveal the interior of the Earth. This meeting is an opportunity to adapt the efforts of detection to the real needs of geophysicists and geochemists (sources of radiogenic heat, potassium in the court, feathers.) Finally more futuristic topics such as the detection of nuclear explosions, of low powers, are also discussed. This document gathers only the slides of the presentations.

  20. On the role of the J-E constitutive relationship in applied geoelectromagnetism

    Directory of Open Access Journals (Sweden)

    D. Patella


    Full Text Available In current applications of the Induced Polarization (IP method, the Debye and Cole-Cole models are used to study relaxation and dispersion properties of rocks, though it is believed that this type of modelisation is confused and vague, because of the lack of a background physical description. In this paper, we show that the Debye model can physically be deduced as a consequence of the electrodynamic behaviour of a mixture of bound and unbound charged particles immersed in an external electric field. We also clarify that the Cole-Cole model is a synthetic model, which can physically be explained as a continuous distribution of Debye terms.

  1. Analisando a implementação de uma abordagem CTS na sala de aula de química Analysing a teaching sequence with STS approach applied in the chemistry classroom

    Directory of Open Access Journals (Sweden)

    Ruth do Nascimento Firme


    Full Text Available Neste artigo, analisamos como dois professores de química desenvolveram, em sala de aula, uma intervenção didática previamente planejada com enfoque CTS, buscando identificar obstáculos e dificuldades para o estabelecimento de uma prática docente pautada nessa perspectiva de ensino. As aulas foram filmadas, transcritas e os dados analisados a partir da dinâmica discursiva estabelecida entre professores e alunos. A análise apontou que dificuldades no desenvolvimento das atividades podem estar associadas não somente à prática docente, mas também a fatores tais como: ausência de informações técnicas e científicas sobre o tema; velocidade da inovação tecnológica; complexidade cientifica na abordagem de alguns temas; dificuldade em articular adequadamente conceitos científicos com questões tecnológicas, associadas a um tema social relevante; e dificuldade de material didático que suporte as discussões de temas específicos na sala de aula.In this work, we have analyzed how two Chemistry's teachers developed a planned teaching sequence starting from a STS perspective in their classrooms, trying to identify obstacles and difficulties in engaging this pedagogical practice and taking into account this perspective for science teaching. Lessons were video recorded, transcribed and data were analyzed considering the discursive dynamic established between the teacher and the students. Data analysis showed that possible obstacles to developing didactic activities cannot be associated only with the teacher's practice and experience, but also can be related to aspects, such as: the lack of technical information about the theme studied; continuous improvement related to the technological artifacts; themes requiring a more complex scientific understanding; difficulties in properly putting together scientific concepts and technology implicated with relevant social problems; and difficulty with appropriate didactical sources to approach

  2. High Throughput Approach Applied to VOC Oxidation at Low Temperature Approche haut débit appliquée à l’oxydation basse température des COV

    Directory of Open Access Journals (Sweden)

    Jolly J.


    Full Text Available A High Throughput (HT approach is used to prepare and characterize the catalytic activity of materials for the destruction of Volatile Organic Compounds (VOC at low temperature. The interest of the Designs of Experiments (DoE in the primary screening is demonstrated through modeling catalysts composition according to the light-off temperature detected by infrared thermography. The combination of the mass spectrometry and the infrared thermography appears very useful to confirm and increase information about catalytic properties of the catalysts extracted to the primary screening stage. Finally, in situ Raman spectroscopy with infrared thermography allows to better understand the origin of the catalytic properties in the case ofAu/CeO2 catalysts. A strong interaction between gold and Ce-O bonds leading to an improvement of the cerium oxide reducibility could explain its high reactivity for 2-propanol oxidation at lower temperature. Une approche haut debit (HD est utilisée de la préparation jusqu’à la caractérisation de l’activité catalytique des matériaux pour l’élimination des Composés Organiques Volatils (COV à basse température. L’intérêt des plans d’expériences (DoE, en anglais Designs of Experiments dans le screening primaire est démontré grâce à l’identification d’une composition optimale de catalyseur prédite à l’aide des différentes températures d’ignition des catalyseurs obtenues par thermographie infrarouge. La combinaison in situ de la spectrométrie de masse et de la thermographie infrarouge s’est avérée d’une grande utilité pour confirmer et augmenter le niveau d’information concernant les propriétés catalytiques des catalyseurs provenant du screening primaire. Enfin, la spectroscopie Raman in situ couplée à la thermographie infrarouge permet de mieux comprendre l’origine des propriétés catalytiques dans le cas du catalyseur Au/CeO2. Une forte interaction entre les particules d

  3. Applied Impact Physics Research (United States)

    Wickert, Matthias


    Applied impact physics research is based on the capability to examine impact processes for a wide range of impact conditions with respect to velocity as well as mass and shape of the projectile. For this reason, Fraunhofer EMI operates a large variety of launchers that address velocities up to ordnance velocities as single stage powder gun but which can also be operated as two-stage light gas guns achieving the regime of low earth orbital velocity. Thereby for projectile masses of up to 100 g hypervelocity impact phenomena up to 7.8 km/s can be addressed. Advanced optical diagnostic techniques like microsecond video are used as commercial systems but - since impact phenomena are mostly related with debris or dust - specialized diagnostics are developed in-house like x-ray cinematography and x-ray tomography. Selected topics of the field of applied impact physics will be presented like the interesting behavior of long rods penetrating low-density materials or experimental findings at hypervelocity for this class of materials as well as new x-ray diagnositic techniques.

  4. Applying lean thinking in construction

    Directory of Open Access Journals (Sweden)

    Remon Fayek Aziz


    Full Text Available The productivity of the construction industry worldwide has been declining over the past 40 years. One approach for improving the situation is using lean construction. Lean construction results from the application of a new form of production management to construction. Essential features of lean construction include a clear set of objectives for the delivery process, aimed at maximizing performance for the customer at the project level, concurrent design, construction, and the application of project control throughout the life cycle of the project from design to delivery. An increasing number of construction academics and professionals have been storming the ramparts of conventional construction management in an effort to deliver better value to owners while making real profits. As a result, lean-based tools have emerged and have been successfully applied to simple and complex construction projects. In general, lean construction projects are easier to manage, safer, completed sooner, and cost less and are of better quality. Significant research remains to complete the translation to construction of lean thinking in Egypt. This research will discuss principles, methods, and implementation phases of lean construction showing the waste in construction and how it could be minimized. The Last Planner System technique, which is an important application of the lean construction concepts and methodologies and is more prevalent, proved that it could enhance the construction management practices in various aspects. Also, it is intended to develop methodology for process evaluation and define areas for improvement based on lean approach principles.

  5. Informatics applied to cytology

    Directory of Open Access Journals (Sweden)

    Pantanowitz Liron


    Full Text Available Automation and emerging information technologies are being adopted by cytology laboratories to augment Pap test screening and improve diagnostic accuracy. As a result, informatics, the application of computers and information systems to information management, has become essential for the successful operation of the cytopathology laboratory. This review describes how laboratory information management systems can be used to achieve an automated and seamless workflow process. The utilization of software, electronic databases and spreadsheets to perform necessary quality control measures are discussed, as well as a Lean production system and Six Sigma approach, to reduce errors in the cytopathology laboratory.

  6. Applied Bayesian modelling

    CERN Document Server

    Congdon, Peter


    This book provides an accessible approach to Bayesian computing and data analysis, with an emphasis on the interpretation of real data sets. Following in the tradition of the successful first edition, this book aims to make a wide range of statistical modeling applications accessible using tested code that can be readily adapted to the reader's own applications. The second edition has been thoroughly reworked and updated to take account of advances in the field. A new set of worked examples is included. The novel aspect of the first edition was the coverage of statistical modeling using WinBU

  7. Applied systems theory

    CERN Document Server

    Dekkers, Rob


    Offering an up-to-date account of systems theories and its applications, this book provides a different way of resolving problems and addressing challenges in a swift and practical way, without losing overview and not having a grip on the details. From this perspective, it offers a different way of thinking in order to incorporate different perspectives and to consider multiple aspects of any given problem. Drawing examples from a wide range of disciplines, it also presents worked cases to illustrate the principles. The multidisciplinary perspective and the formal approach to modelling of syst

  8. Positive Behavior Support and Applied Behavior Analysis (United States)

    Johnston, J. M.; Foxx, R. M.; Jacobson, J. W.; Green, G.; Mulick, J. A.


    This article reviews the origins and characteristics of the positive behavior support (PBS) movement and examines those features in the context of the field of applied behavior analysis (ABA). We raise a number of concerns about PBS as an approach to delivery of behavioral services and its impact on how ABA is viewed by those in human services. We…

  9. Traditional and Applied Graduate Education: Special Challenges. (United States)

    Powers, William G.; Love, Don E.


    Addresses the differences in philosophy and instruction methods while offering a means of complementary support. Discusses the traditional and applied communication graduate education models. Concludes that educators must establish and focus upon mutual respect for the commonalities held by the two approaches to graduate education and the support…

  10. Applied Biomechanics in an Instructional Setting (United States)

    Hudson, Jackie L.


    Biomechanics is the science of how people move better, meaning more skillfully and more safely. This article places more emphasis on skill rather than safety, though there are many parallels between them. It shares a few features of the author's paradigm of applied biomechanics and discusses an integrated approach toward a middle school football…

  11. Applied partial differential equations

    CERN Document Server

    Logan, J David


    This text presents the standard material usually covered in a one-semester, undergraduate course on boundary value problems and PDEs.  Emphasis is placed on motivation, concepts, methods, and interpretation, rather than on formal theory. The concise treatment of the subject is maintained in this third edition covering all the major ideas: the wave equation, the diffusion equation, the Laplace equation, and the advection equation on bounded and unbounded domains. Methods include eigenfunction expansions, integral transforms, and characteristics. In this third edition, text remains intimately tied to applications in heat transfer, wave motion, biological systems, and a variety other topics in pure and applied science. The text offers flexibility to instructors who, for example, may wish to insert topics from biology or numerical methods at any time in the course. The exposition is presented in a friendly, easy-to-read, style, with mathematical ideas motivated from physical problems. Many exercises and worked e...

  12. Applied number theory

    CERN Document Server

    Niederreiter, Harald


    This textbook effectively builds a bridge from basic number theory to recent advances in applied number theory. It presents the first unified account of the four major areas of application where number theory plays a fundamental role, namely cryptography, coding theory, quasi-Monte Carlo methods, and pseudorandom number generation, allowing the authors to delineate the manifold links and interrelations between these areas.  Number theory, which Carl-Friedrich Gauss famously dubbed the queen of mathematics, has always been considered a very beautiful field of mathematics, producing lovely results and elegant proofs. While only very few real-life applications were known in the past, today number theory can be found in everyday life: in supermarket bar code scanners, in our cars’ GPS systems, in online banking, etc.  Starting with a brief introductory course on number theory in Chapter 1, which makes the book more accessible for undergraduates, the authors describe the four main application areas in Chapters...

  13. Applied mechanics of solids

    CERN Document Server

    Bower, Allan F


    Modern computer simulations make stress analysis easy. As they continue to replace classical mathematical methods of analysis, these software programs require users to have a solid understanding of the fundamental principles on which they are based. Develop Intuitive Ability to Identify and Avoid Physically Meaningless Predictions Applied Mechanics of Solids is a powerful tool for understanding how to take advantage of these revolutionary computer advances in the field of solid mechanics. Beginning with a description of the physical and mathematical laws that govern deformation in solids, the text presents modern constitutive equations, as well as analytical and computational methods of stress analysis and fracture mechanics. It also addresses the nonlinear theory of deformable rods, membranes, plates, and shells, and solutions to important boundary and initial value problems in solid mechanics. The author uses the step-by-step manner of a blackboard lecture to explain problem solving methods, often providing...

  14. Applied multivariate statistical analysis

    CERN Document Server

    Härdle, Wolfgang Karl


    Focusing on high-dimensional applications, this 4th edition presents the tools and concepts used in multivariate data analysis in a style that is also accessible for non-mathematicians and practitioners.  It surveys the basic principles and emphasizes both exploratory and inferential statistics; a new chapter on Variable Selection (Lasso, SCAD and Elastic Net) has also been added.  All chapters include practical exercises that highlight applications in different multivariate data analysis fields: in quantitative financial studies, where the joint dynamics of assets are observed; in medicine, where recorded observations of subjects in different locations form the basis for reliable diagnoses and medication; and in quantitative marketing, where consumers’ preferences are collected in order to construct models of consumer behavior.  All of these examples involve high to ultra-high dimensions and represent a number of major fields in big data analysis. The fourth edition of this book on Applied Multivariate ...

  15. Micromechanical modelling of heterogeneous materials in transient conditions: contributions for the study of the ageing of structural components under service; Modelisation micromecanique des materiaux heterogenes en regimes transitoires: contributions en vue de l'etude du vieillissement des structures en service

    Energy Technology Data Exchange (ETDEWEB)

    Masson, R.


    considering the particular situation where regions of the representative volume element have ill-defined mechanical properties. In the linear elastic case, new bounds for the effective behaviour are derived by marrying the structural analysis and a variational approach. This last work opens on important prospects for further works: more tightened bounds, nonlinear behaviours,... Considering homogenisation methods, further works are precisely defined, in particular for polycrystalline materials. In that situation, the field of investigation widens clearly (Fatigue, Large strains,...) thanks to the internal variables formulation proposed. Lastly, the simulation of irradiation effects constitutes the third topic of interest for the years to come, the general objective being to better predict the effects of the swelling strains induced by irradiation on the behaviour of structural components under service. (author) [French] La modelisation du comportement mecanique des materiaux de structure se nourrit de plus en plus de parametres microstructuraux. Dans ce cadre, les methodes d'homogeneisation presentent l'avantage de fournir des methodes deductives qui, a partir des proprietes et de la repartition spatiale des heterogeneites, deduisent les proprietes effectives du materiau considere. Neanmoins de nombreuses applications soulevent encore des difficultes. C'est en particulier le cas des materiaux de structure presentant un comportement elasto-viscoplastique et soumis a un trajet de chargement non monotone et non isotherme. Progresser sur le traitement par homogeneisation de ces situations concretes constitue precisement le fil conducteur des differentes contributions presentees dans ce memoire d'HDR. Dans le cas elastique lineaire, de nouvelles expressions pour le calcul du tenseur d'Eshelby sont tout d'abord etablies afin d'ameliorer l'efficacite des methodes d'homogeneisation habituellement proposees. Toujours pour des comportements

  16. Applied cost allocation

    DEFF Research Database (Denmark)

    Bogetoft, Peter; Hougaard, Jens Leth; Smilgins, Aleksandrs


    This paper deals with empirical computation of Aumann–Shapley cost shares for joint production. We show that if one uses a mathematical programing approach with its non-parametric estimation of the cost function there may be observations in the data set for which we have multiple Aumann......–Shapley prices. We suggest to overcome such problems by using lexicographic goal programing techniques. Moreover, cost allocation based on the cost function is unable to account for differences between efficient and actual cost. We suggest to employ the notion of rational inefficiency in order to supply a set...... of assumptions concerning firm behavior. These assumptions enable us to connect inefficient with efficient production and thereby provide consistent ways of allocating the costs arising from inefficiency....

  17. Applied Linguistics and the "Annual Review of Applied Linguistics." (United States)

    Kaplan, Robert B.; Grabe, William


    Examines the complexities and differences involved in granting disciplinary status to the role of applied linguistics, discusses the role of the "Annual Review of Applied Linguistics" as a contributor to the development of applied linguistics, and highlights a set of publications for the future of applied linguistics. (Author/VWL)

  18. Bootstrapping in Applied Linguistics: Assessing Its Potential Using Shared Data (United States)

    Plonsky, Luke; Egbert, Jesse; Laflair, Geoffrey T.


    Parametric analyses such as t tests and ANOVAs are the norm--if not the default--statistical tests found in quantitative applied linguistics research (Gass 2009). Applied statisticians and one applied linguist (Larson-Hall 2010, 2012; Larson-Hall and Herrington 2010), however, have argued that this approach may not be appropriate for small samples…

  19. Quantification of the emissions of the ozone preceding by inverse modelization. Final report; Quantification des emissions des precurseurs de l'ozone par modelisation inverse. Rapport final

    Energy Technology Data Exchange (ETDEWEB)

    Granier, C.; Petron, G. [Institut Pierre Simon Laplace (IPSL), Service d' Aeronomie, 75 - Paris (France); Ciais, Ph.; Bousquet, Ph. [Institut Pierre Simon Laplace (IPSL), Lab. des Sciences du Climat et de l' Environnement, 75 - Paris (France)


    In the framework of this work, inverse methods have been developed and applied for two types of applications: climatological observations to optimize the monthly average of the observed compounds; the distribution of the carbon monoxide. The report presents the experimental methodologies, the used simulation and the results. (A.L.B.)

  20. Applied hydraulic transients

    CERN Document Server

    Chaudhry, M Hanif


    This book covers hydraulic transients in a comprehensive and systematic manner from introduction to advanced level and presents various methods of analysis for computer solution. The field of application of the book is very broad and diverse and covers areas such as hydroelectric projects, pumped storage schemes, water-supply systems, cooling-water systems, oil pipelines and industrial piping systems. Strong emphasis is given to practical applications, including several case studies, problems of applied nature, and design criteria. This will help design engineers and introduce students to real-life projects. This book also: ·         Presents modern methods of analysis suitable for computer analysis, such as the method of characteristics, explicit and implicit finite-difference methods and matrix methods ·         Includes case studies of actual projects ·         Provides extensive and complete treatment of governed hydraulic turbines ·         Presents design charts, desi...

  1. Academic training: Applied superconductivity

    CERN Multimedia


    LECTURE SERIES 17, 18, 19 January from 11.00 to 12.00 hrs Council Room, Bldg 503 Applied Superconductivity : Theory, superconducting Materials and applications E. PALMIERI/INFN, Padova, Italy When hearing about persistent currents recirculating for several years in a superconducting loop without any appreciable decay, one realizes that we are dealing with a phenomenon which in nature is the closest known to the perpetual motion. Zero resistivity and perfect diamagnetism in Mercury at 4.2 K, the breakthrough during 75 years of several hundreds of superconducting materials, the revolution of the "liquid Nitrogen superconductivity"; the discovery of still a binary compound becoming superconducting at 40 K and the subsequent re-exploration of the already known superconducting materials: Nature discloses drop by drop its intimate secrets and nobody can exclude that the last final surprise must still come. After an overview of phenomenology and basic theory of superconductivity, the lectures for this a...

  2. Applied Historical Astronomy (United States)

    Stephenson, F. Richard


    F. Richard Stephenson has spent most of his research career -- spanning more than 45 years -- studying various aspects of Applied Historical Astronomy. The aim of this interdisciplinary subject is the application of historical astronomical records to the investigation of problems in modern astronomy and geophysics. Stephenson has almost exclusively concentrated on pre-telescopic records, especially those preserved from ancient and medieval times -- the earliest reliable observations dating from around 700 BC. The records which have mainly interested him are of eclipses (both solar and lunar), supernovae, sunspots and aurorae, and Halley's Comet. The main sources of early astronomical data are fourfold: records from ancient and medieval East Asia (China, together with Korea and Japan); ancient Babylon; ancient and medieval Europe; and the medieval Arab world. A feature of Stephenson's research is the direct consultation of early astronomical texts in their original language -- either working unaided or with the help of colleagues. He has also developed a variety of techniques to help interpret the various observations. Most pre-telescopic observations are very crude by present-day standards. In addition, early motives for skywatching were more often astrological rather than scientific. Despite these drawbacks, ancient and medieval astronomical records have two remarkable advantages over modern data. Firstly, they can enable the investigation of long-term trends (e.g. in the terrestrial rate of rotation), which in the relatively short period covered by telescopic observations are obscured by short-term fluctuations. Secondly, over the lengthy time-scale which they cover, significant numbers of very rare events (such as Galactic supernovae) were reported, which have few -- if any-- counterparts in the telescopic record. In his various researches, Stephenson has mainly focused his attention on two specific topics. These are: (i) long-term changes in the Earth's rate of

  3. Essays in applied microeconomics (United States)

    Wang, Xiaoting

    In this dissertation I use Microeconomic theory to study firms' behavior. Chapter One introduces the motivations and main findings of this dissertation. Chapter Two studies the issue of information provision through advertisement when markets are segmented and consumers' price information is incomplete. Firms compete in prices and advertising strategies for consumers with transportation costs. High advertising costs contribute to market segmentation. Low advertising costs promote price competition among firms and improves consumer welfare. Chapter Three also investigates market power as a result of consumers' switching costs. A potential entrant can offer a new product bundled with an existing product to compensate consumers for their switching cost. If the primary market is competitive, bundling simply plays the role of price discrimination, and it does not dominate unbundled sales in the process of entry. If the entrant has market power in the primary market, then bundling also plays the role of leveraging market power and it dominates unbundled sales. The market for electric power generation has been opened to competition in recent years. Chapter Four looks at issues involved in the deregulated electricity market. By comparing the performance of the competitive market with the social optimum, we identify the conditions under which market equilibrium generates socially efficient levels of electric power. Chapter Two to Four investigate the strategic behavior among firms. Chapter Five studies the interaction between firms and unemployed workers in a frictional labor market. We set up an asymmetric job auction model, where two types of workers apply for two types of job openings by bidding in auctions and firms hire the applicant offering them the most profits. The job auction model internalizes the determination of the share of surplus from a match, therefore endogenously generates incentives for an efficient division of the matching surplus. Microeconomic

  4. Applied large eddy simulation. (United States)

    Tucker, Paul G; Lardeau, Sylvain


    Large eddy simulation (LES) is now seen more and more as a viable alternative to current industrial practice, usually based on problem-specific Reynolds-averaged Navier-Stokes (RANS) methods. Access to detailed flow physics is attractive to industry, especially in an environment in which computer modelling is bound to play an ever increasing role. However, the improvement in accuracy and flow detail has substantial cost. This has so far prevented wider industrial use of LES. The purpose of the applied LES discussion meeting was to address questions regarding what is achievable and what is not, given the current technology and knowledge, for an industrial practitioner who is interested in using LES. The use of LES was explored in an application-centred context between diverse fields. The general flow-governing equation form was explored along with various LES models. The errors occurring in LES were analysed. Also, the hybridization of RANS and LES was considered. The importance of modelling relative to boundary conditions, problem definition and other more mundane aspects were examined. It was to an extent concluded that for LES to make most rapid industrial impact, pragmatic hybrid use of LES, implicit LES and RANS elements will probably be needed. Added to this further, highly industrial sector model parametrizations will be required with clear thought on the key target design parameter(s). The combination of good numerical modelling expertise, a sound understanding of turbulence, along with artistry, pragmatism and the use of recent developments in computer science should dramatically add impetus to the industrial uptake of LES. In the light of the numerous technical challenges that remain it appears that for some time to come LES will have echoes of the high levels of technical knowledge required for safe use of RANS but with much greater fidelity.

  5. A damage model of Zr {alpha} under cyclic loading at 200 degree Celsius; Modelisation de l`endommagement du Zr {alpha} sous chargement cyclique a 200 deg C

    Energy Technology Data Exchange (ETDEWEB)

    Vogel, C.; Drubay, B. [CEA Centre d`Etudes de Saclay, 91 - Gif-sur-Yvette (France). Dept. de Mecanique et de Technologie; Cailletaud, G. [Ecole Nationale Superieure des Mines, 75 - Paris (France); Mottot, M. [CEA Centre d`Etudes de Saclay, 91 - Gif-sur-Yvette (France). Direction des Technologies Avancees


    A damage model for anticipating zirconium {alpha} test-piece rupture under cyclic solicitations at 200 degree Celsius is presented. The article is divided into three parts : an experimental approach, the damage model presentation and the application of this model. (O.L.). 10 refs., 7 figs., 4 tabs.

  6. Process Approach to Teaching Writing Applied in Different Teaching Models (United States)

    Sun, Chunling; Feng, Guoping


    English writing, as a basic language skill for second language learners, is being paid close attention to. How to achieve better results in English teaching and how to develop students' writing competence remain an arduous task for English teachers. Based on the review of the concerning literature from other researchers as well as a summery of the…

  7. Applying generalized non deducibility on compositions (GNDC) approach in dependability

    NARCIS (Netherlands)

    Gnesi, Stefania; Lenzini, Gabriele; Martinelli, Fabio


    This paper presents a framework where dependable systems can be uniformly modeled and dependable properties analyzed within the Generalized Non Deducibility on Compositions (GNDC), a scheme that has been profitably used in definition and analysis of security properties. Precisely, our framework requ

  8. Applying Resilience Concepts in Forest Management: A Retrospective Simulation Approach

    Directory of Open Access Journals (Sweden)

    Caren C. Dymond


    Full Text Available Increasing the resilience of ecological and sociological systems has been proposed as an option to adapt to changing future climatic conditions. However, few studies test the applicability of those strategies to forest management. This paper uses a real forest health incident to assess the ability of forest management strategies to affect ecological and economic resilience of the forest. Two landscape scale strategies are compared to business as usual management for their ability to increase resilience to a climate-change induced mountain pine beetle outbreak in the Kamloops Timber Supply Area, British Columbia, Canada for the period 1980 to 2060. Proactive management to reduce high risk species while maintaining or increasing diversity through reforestation was found to be more resilient in terms of the metrics: post-disturbance growing stock, improved volume and stability of timber flow, and net revenue. However, landscape-scale indicators of diversity were little affected by management. Our results were robust to uncertainty in tree growth rates and timber value and show that adapting to climate change through improving the resilience of forested landscapes is an economically viable option.

  9. Semantic Approaches Applied to Scientific Ocean Drilling Data (United States)

    Fils, D.; Jenkins, C. J.; Arko, R. A.


    The application of Linked Open Data methods to 40 years of data from scientific ocean drilling is providing users with several new methods for rich-content data search and discovery. Data from the Deep Sea Drilling Project (DSDP), Ocean Drilling Program (ODP) and Integrated Ocean Drilling Program (IODP) have been translated and placed in RDF triple stores to provide access via SPARQL, linked open data patterns, and by embedded structured data through / RDFa. Existing search services have been re-encoded in this environment which allows the new and established architectures to be contrasted. Vocabularies including computed semantic relations between concepts, allow separate but related data sets to be connected on their concepts and resources even when they are expressed somewhat differently. Scientific ocean drilling produces a wide range of data types and data sets: borehole logging file-based data, images, measurements, visual observations and the physical sample data. The steps involved in connecting these data to concepts using vocabularies will be presented, including the connection of data sets through Vocabulary of Interlinked Datasets (VoID) and open entity collections such as Freebase and dbPedia. Demonstrated examples will include: (i) using RDF Schema for inferencing and in federated searches across NGDC and IODP data, (ii) using structured data in the web site, (iii) association through semantic methods of age models and depth recorded data to facilitate age based searches for data recorded by depth only.

  10. An Analytical Model for Learning: An Applied Approach. (United States)

    Kassebaum, Peter Arthur

    A mediated-learning package, geared toward non-traditional students, was developed for use in the College of Marin's cultural anthropology courses. An analytical model for learning was used in the development of the package, utilizing concepts related to learning objectives, programmed instruction, Gestalt psychology, cognitive psychology, and…

  11. The Case Study Approach: Some Theoretical, Methodological and Applied Considerations (United States)


    study research design by drawing linkages between ontology (nature or essence of particular social phenomena), epistemology (the theory gathered during a site visit, and can include various physical or cultural artefacts such as tools, instruments, art works, and computer output...organisations in New Zealand. A wide range of New Zealand organisations were included covering food processing; whiteware manufacture, computer consultancy

  12. A Multiobjective Approach Applied to the Protein Structure Prediction Problem (United States)


    in that space. F.1.4 Crossover. Meiosis and Mitosis both can perform the function of cell division. Cells spend most of their life in this life...function, also know as Interphase. Meiosis is the formation of gametes in sexual reproduction always yielding a doubling of the chromosome number. There is...chromosomes in the gamete-forming cells to be halved. This is normally accom- plished during the process of meiosis and results in the production of

  13. A Model-based Prognostics Approach Applied to Pneumatic Valves (United States)

    National Aeronautics and Space Administration — Within the area of systems health management, the task of prognostics centers on predicting when components will fail. Model-based prognostics exploits domain...

  14. A Model-Based Prognostics Approach Applied to Pneumatic Valves (United States)

    National Aeronautics and Space Administration — Within the area of systems health management, the task of prognostics centers on predicting when components will fail. Model-based prognostics exploits domain...

  15. Sinking in Quicksand: An Applied Approach to the Archimedes Principle (United States)

    Evans, G. M.; Evans, S. C.; Moreno-Atanasio, R.


    The objective of this paper is to present a laboratory experiment that explains the phenomenon of sinking in quicksand simulated as a fluidized bed. The paper demonstrates experimentally and theoretically that the proportion of a body that sinks in quicksand depends on the volume fraction of solids and the density of the body relative to the…

  16. Applying Newton's Apple to Elementary Physical Education: An Interdisciplinary Approach (United States)

    Gagen, Linda; Getchell, Nancy


    The NASPE standards for physical education programs stress that students should not only achieve competence in physical skills but also acquire and integrate the underlying concepts that can lead to effective movement. Physical educators can successfully embed these underlying concepts into the daily skill instruction and guided practice in their…

  17. Computational challenges of structure-based approaches applied to HIV. (United States)

    Forli, Stefano; Olson, Arthur J


    Here, we review some of the opportunities and challenges that we face in computational modeling of HIV therapeutic targets and structural biology, both in terms of methodology development and structure-based drug design (SBDD). Computational methods have provided fundamental support to HIV research since the initial structural studies, helping to unravel details of HIV biology. Computational models have proved to be a powerful tool to analyze and understand the impact of mutations and to overcome their structural and functional influence in drug resistance. With the availability of structural data, in silico experiments have been instrumental in exploiting and improving interactions between drugs and viral targets, such as HIV protease, reverse transcriptase, and integrase. Issues such as viral target dynamics and mutational variability, as well as the role of water and estimates of binding free energy in characterizing ligand interactions, are areas of active computational research. Ever-increasing computational resources and theoretical and algorithmic advances have played a significant role in progress to date, and we envision a continually expanding role for computational methods in our understanding of HIV biology and SBDD in the future.

  18. Applying a Common-Sense Approach to Fighting Obesity

    Directory of Open Access Journals (Sweden)

    Jessica Y. Breland


    Full Text Available The obesity epidemic is a threat to the health of millions and to the economic viability of healthcare systems, governments, businesses, and nations. A range of answers come to mind if and when we ask, “What can we, health professionals (physicians, nurses, nutritionists, behavioral psychologists, do about this epidemic?” In this paper, we describe the Common-Sense Model of Self-Regulation as a framework for organizing existent tools and creating new tools to improve control of the obesity epidemic. Further, we explain how the Common-Sense Model can augment existing behavior-change models, with particular attention to the strength of the Common-Sense Model in addressing assessment and weight maintenance beyond initial weight loss.

  19. Applying a Common-Sense Approach to Fighting Obesity (United States)

    Breland, Jessica Y.; Fox, Ashley M.; Horowitz, Carol R.; Leventhal, Howard


    The obesity epidemic is a threat to the health of millions and to the economic viability of healthcare systems, governments, businesses, and nations. A range of answers come to mind if and when we ask, “What can we, health professionals (physicians, nurses, nutritionists, behavioral psychologists), do about this epidemic?” In this paper, we describe the Common-Sense Model of Self-Regulation as a framework for organizing existent tools and creating new tools to improve control of the obesity epidemic. Further, we explain how the Common-Sense Model can augment existing behavior-change models, with particular attention to the strength of the Common-Sense Model in addressing assessment and weight maintenance beyond initial weight loss. PMID:22811889

  20. Applying Sustainable Systems Development Approach to Educational Technology Systems (United States)

    Huang, Albert


    Information technology (IT) is an essential part of modern education. The roles and contributions of technology to education have been thoroughly documented in academic and professional literature. Despite the benefits, the use of educational technology systems (ETS) also creates a significant impact on the environment, primarily due to energy…

  1. Person-job fit applied to teamwork - A multilevel approach

    NARCIS (Netherlands)

    Molleman, E; Nauta, A; Jehn, KA


    This study examined the moderating role of team task autonomy on the relationship between the mean level of three personality traits in a team-conscientiousness, emotional stability, and openness to experience-and two individual outcomes-job satisfaction and learning. Questionnaire data were collect

  2. Applying open source innovation approaches in developing business innovation

    DEFF Research Database (Denmark)

    Aagaard, Annabeth; Lindgren, Peter


    More and more companies are pursuing continuous innovation through different types of open source innovation and across different partners. The growing interest in open innovation (OI) originates both from the academic community as well as amongst practitioners motivating further investigation...... of effective OI and its different applications. One of the OI applications receiving growing attention is the use of innovation contests in developing business model innovations. However little theoretical knowledge exists and limited empirical research has been performed on OI and how this is facilitated...... and managed effectively in developing business model innovation. The aim of this paper is therefore to close this research gap and to provide new knowledge within the research field of OI and OI applications. Thus, in the present study we explore the facilitation and management of open source innovation...

  3. Essays in Applied Microeconomics (United States)

    Ge, Qi

    This dissertation consists of three self-contained applied microeconomics essays on topics related to behavioral economics and industrial organization. Chapter 1 studies how sentiment as a result of sports event outcomes affects consumers' tipping behavior in the presence of social norms. I formulate a model of tipping behavior that captures consumer sentiment following a reference-dependent preference framework and empirically test its relevance using the game outcomes of the NBA and the trip and tipping data on New York City taxicabs. While I find that consumers' tipping behavior responds to unexpected wins and losses of their home team, particularly in close game outcomes, I do not find evidence for loss aversion. Coupled with the findings on default tipping, my empirical results on the asymmetric tipping responses suggest that while social norms may dominate loss aversion, affect and surprises can result in freedom on the upside of tipping. Chapter 2 utilizes a novel data source of airline entry and exit announcements and examines how the incumbent airlines adjust quality provisions as a response to their competitors' announcements and the role of timing in such responses. I find no evidence that the incumbents engage in preemptive actions when facing probable entry and exit threats as signaled by the competitors' announcements in either short term or long term. There is, however, evidence supporting their responses to the competitors' realized entry or exit. My empirical findings underscore the role of timing in determining preemptive actions and suggest that previous studies may have overestimated how the incumbent airlines respond to entry threats. Chapter 3, which is collaborated with Benjamin Ho, investigates the habit formation of consumers' thermostat setting behavior, an often implicitly made decision and yet a key determinant of home energy consumption and expenditures. We utilize a high frequency dataset on household thermostat usage and find that

  4. Morphometrics applied to medical entomology. (United States)

    Dujardin, Jean-Pierre


    Morphometrics underwent a revolution more than one decade ago. In the modern morphometrics, the estimate of size is now contained in a single variable reflecting variation in many directions, as many as there are landmarks under study, and shape is defined as their relative positions after correcting for size, position and orientation. With these informative data, and the corresponding software freely available to conduct complex analyses, significant biological and epidemiological features can be quantified more accurately. We discuss the evolutionary significance of the environmental impact on metric variability, mentioning the importance of concepts like genetic assimilation, genetic accommodation, and epigenetics. We provide examples of measuring the effect of selection on metric variation by comparing (unpublished) Qst values with corresponding (published) Fst. The primary needs of medical entomologists are to distinguish species, especially cryptic species, and to detect them where they are not expected. We explain how geometric morphometrics could apply to these questions, and where there are deficiencies preventing the approach from being utilized at its maximum potential. Medical entomologists in connection with control programs aim to identify isolated populations where the risk of reinfestation after treatment would be low ("biogeographical islands"). Identifying them can be obtained from estimating the number of migrants per generation. Direct assessment of movement remains the most valid approach, but it scores active movement only. Genetic methods estimating gene flow levels among interbreeding populations are commonly used, but gene flow does not necessarily mean the current flow of migrants. Methods using the morphometric variation are neither suited to evaluate gene flow, nor are they adapted to estimate the flow of migrants. They may provide, however, the information needed to create a preliminary map pointing to relevant areas where one could

  5. Computer simulations applied in materials

    Energy Technology Data Exchange (ETDEWEB)



    This workshop takes stock of the simulation methods applied to nuclear materials and discusses the conditions in which these methods can predict physical results when no experimental data are available. The main topic concerns the radiation effects in oxides and includes also the behaviour of fission products in ceramics, the diffusion and segregation phenomena and the thermodynamical properties under irradiation. This document brings together a report of the previous 2002 workshop and the transparencies of 12 presentations among the 15 given at the workshop: accommodation of uranium and plutonium in pyrochlores; radiation effects in La{sub 2}Zr{sub 2}O{sub 7} pyrochlores; first principle calculations of defects formation energies in the Y{sub 2}(Ti,Sn,Zr){sub 2}O{sub 7} pyrochlore system; an approximate approach to predicting radiation tolerant materials; molecular dynamics study of the structural effects of displacement cascades in UO{sub 2}; composition defect maps for A{sup 3+}B{sup 3+}O{sub 3} perovskites; NMR characterization of radiation damaged materials: using simulation to interpret the data; local structure in damaged zircon: a first principle study; simulation studies on SiC; insertion and diffusion of He in 3C-SiC; a review of helium in silica; self-trapped holes in amorphous silicon dioxide: their short-range structure revealed from electron spin resonance and optical measurements and opportunities for inferring intermediate range structure by theoretical modelling. (J.S.)

  6. SPSS for applied sciences basic statistical testing

    CERN Document Server

    Davis, Cole


    This book offers a quick and basic guide to using SPSS and provides a general approach to solving problems using statistical tests. It is both comprehensive in terms of the tests covered and the applied settings it refers to, and yet is short and easy to understand. Whether you are a beginner or an intermediate level test user, this book will help you to analyse different types of data in applied settings. It will also give you the confidence to use other statistical software and to extend your expertise to more specific scientific settings as required.The author does not use mathematical form

  7. Nonlinear phenomena in wave-body interaction: description and theoretical modeling; Les effets non-lineaires en interaction houle-structure et leur modelisation

    Energy Technology Data Exchange (ETDEWEB)

    Molin, B. [Ecole Generaliste d' Ingenieurs de Marseille, 13 (France)


    At first approximation, the study of wave interaction with fixed or floating bodies is carried out within a linear frame. However nonlinear effects are numerous and they have diverse origins: mechanical nonlinearities, variation in time of the wetted part of the hull, viscous phenomena (flow separation), nonlinear free surface equations. We focus here on the latter type of nonlinearities. Two different approaches are described, both being based on potential flow theory. Practical applications are given for two basic geometries: a vertical cylinder and a vertical plate, perpendicular to the wave direction. In the first approach, one proceeds through successive approximations, based on a perturbation series development. The first-order of approximation coincides with the linear theory. The main interest of the second-order of approximation, well mastered nowadays, is that it yields excitation loads in an enlarged frequency domain, encompassing most of the natural frequencies of the system considered. At third-order the complexity of the equations becomes dissuasive and few researchers have ventured there. We suggest that third-order (or tertiary) interactions, between incoming waves and reflected waves by the structure, can play a very important role, overlooked so far, in phenomena such as run-up or green water. In the second approach one integrates in time and space the nonlinear equations of the initial boundary value problem, with the free surface equations being exactly satisfied. In this way one obtains numerical equivalents of the physical wave-tanks. They are briefly described and some illustrative results are given. (authors)

  8. Essays in Applied Microeconomics (United States)

    Severnini, Edson Roberto

    , I find relatively small costs of environmental regulations associated with hydroelectric licensing rules. In Chapter 2, I study the joint choice of spouse and location made by individuals at the start of their adult lives. I assume that potential spouses meet in a marriage market and decide who to marry and where they will live, taking account of varying economic opportunities in different locations and inherent preferences for living near the families of both spouses. I develop a theoretical framework that incorporates a collective model of household allocation, conditional on the choice of spouse and location, with a forward-looking model of the marriage market that allows for the potential inability of spouses to commit to a particular intra-household sharing rule. I address the issue of unobserved heterogeneity in the tastes of husbands and wives using a control-function approach that assumes there is a one-to-one mapping between unobserved preferences of the two spouses and their labor supply choices. Estimation results for young dual-career households in the 2000 Census lead to three main findings. First, I find excess sensitivity of the sharing rule that governs the allocation of resources among couples to the conditions in the location they actually choose, implying that spouses cannot fully commit to a sharing rule. Second, I show that the lack of commitment has a relatively larger effect on the share of family resources received by women. Third, I find that the failure of full commitment can explain nearly all of the gap in the interstate migration rates of single and married people in the U.S. Finally, in Chapter 3, I examine unintended consequences of environmental regulations affecting the location of power plants. I present evidence that while hydroelectric licensing rules do conserve the wilderness and the wildlife by restricting the development of hydro projects in some counties, they lead to more greenhouse gas emissions in those same locations

  9. On the numerical simulation of uncertain parameters in a radionuclide transport model; Modelisation numerique de parametres incertains associes a un modele de transport de radionucleides

    Energy Technology Data Exchange (ETDEWEB)

    Diaz Moreno, J.M.; Ortegon Gallego, F. [Universidad de Cadiz, Dept. de Matematicas, CASEM (Spain); Lazaar, S. [Universite AbdelMalek Essaadi, Ecole Nationale des Sciences Appliquees, Dept. de Mathematiques et Informatique, Tanger Principale (Morocco)


    We study a fast algorithm to generate random fields which represent the uncertain parameters in a transport model of radionuclides in the geosphere. This algorithm has been introduced by Mikhailov and is based on a procedure known as Palm process. It can then be applied in a Monte Carlo method in the probabilistic risk assessment of high-level radioactive waste disposal in deep formation. We use this algorithm in order to compute the retardation factor appearing in the radionuclide migration model and we compare the CPU time corresponding to this procedure versus a classical spectral method. (authors)

  10. Two-dimensional modeling of sediments deposits in dam reservoirs in Algeria; Modelisation bidimensionnelle du depot de sediments dans un barrage en Algerie

    Energy Technology Data Exchange (ETDEWEB)

    Bessenasse, M. [Universite SAAD Dahleb (Blida), Lab. de Recherche des Sciences de l' Eau LRS EAU ENP, Alger (Algeria); Kettab, A. [Ecole Nationale Polytechnique, LRS-EAU, Alger (Algeria); Paquier, A. [Cemagref de Lyon, Unite de Recherche Hydrologie-Hydraulique, 69 (France)


    The method to build a numerical model intended to predict the formation and the change of sediment deposits upstream from a dam is presented. From information about the inputs of water and sediments coming from the catchment supported by a QdF type hydrological analysis, a horizontal 2-D hydraulic model which couples shallow water equations and one equation for advection and diffusion of sediment concentration is used. Applying this model to Zardezas reservoir in Skikda (Algeria) region shows, on the one hand, the practical difficulties met on such case and, on the other hand, the potentialities of such a method for the management of Algerian reservoirs. (authors)

  11. Kinetics of catalytic reforming with Pt-Sn catalyst; Modelisation cinetique du reformage catalytique sur catalyseur Pt-Sn/Al{sub 2}O{sub 3}

    Energy Technology Data Exchange (ETDEWEB)

    Cochegrue, H.


    Catalytic Reforming is one of the key processes for petrol refining as it produces gasoline with a high octane number and it is a main source of hydrogen. Refiners are asking for more accurate models in order to optimise their plants. An innovative methodology called 'Single Events' is very different from the classical empirical models because it takes into account the various reaction intermediates and reaction pathways. Some hypotheses based on the relative stability of the carbo-cations allow to get a small number of parameters, which are independent of the composition of the feedstock used. The main target of this work was to apply this methodology to the Catalytic Reforming. The single event network had to be first reduced to a late lumped reaction scheme, which incorporates the detailed knowledge of the elementary network while the intermediates and the reaction pathways are reduced: it can be applied now to naphtha feedstock, although the detailed composition is not yet well known. A pilot unit of Catalytic Reforming, which is representative of the industrial processes, was first designed for the kinetic experiments. Experiments with technical heptane were conducted with a fresh catalyst, which was cocked first, and with a used catalyst from a refinery plant. This latter was difficult to use because of its fast deactivation. However, the results obtained allowed to study the influence of the experimental parameters and of the poisoning by iron, and to estimate some of the main kinetic parameters of the model. (author)

  12. Applying System Engineering to Pharmaceutical Safety

    Directory of Open Access Journals (Sweden)

    Nancy Leveson


    Full Text Available While engineering techniques are used in the development of medical devices and have been applied to individual healthcare processes, such as the use of checklists in surgery and ICUs, the application of system engineering techniques to larger healthcare systems is less common. System safety is the part of system engineering that uses modeling and analysis to identify hazards and to design the system to eliminate or control them. In this paper, we demonstrate how to apply a new, safety engineering static and dynamic modeling and analysis approach to healthcare systems. Pharmaceutical safety is used as the example in the paper, but the same approach is potentially applicable to other complex healthcare systems. System engineering techniques can be used in re-engineering the system as a whole to achieve the system goals, including both enhancing the safety of current drugs while, at the same time, encouraging the development of new drugs.

  13. Modeling of a tram power network: from the component to the system; Modelisation d'un reseau electrique de tramway: du composant au systeme

    Energy Technology Data Exchange (ETDEWEB)

    Morin, E.


    The study and the modeling of tram power networks require a system analysis. The use of several power-electronic converters in these networks significantly modifies both their topology and their function. Therefore, modeling methods developed in this thesis differ from traditional approaches, since a global analysis of a system should be linked with the study of its components.To satisfy the demands of the tram domain, this thesis develops modeling methods for transmission lines and transformers. Two levels of analysis are considered. Firstly, the tram power network is evaluated in relation to time. Secondly, an Iterative Harmonic Analysis (IHA) program is developed to compute the spectra of the system accurately. (author)

  14. The Routledge Applied Linguistics Reader (United States)

    Wei, Li, Ed.


    "The Routledge Applied Linguistics Reader" is an essential collection of readings for students of Applied Linguistics. Divided into five sections: Language Teaching and Learning, Second Language Acquisition, Applied Linguistics, Identity and Power and Language Use in Professional Contexts, the "Reader" takes a broad…

  15. The Routledge Applied Linguistics Reader (United States)

    Wei, Li, Ed.


    "The Routledge Applied Linguistics Reader" is an essential collection of readings for students of Applied Linguistics. Divided into five sections: Language Teaching and Learning, Second Language Acquisition, Applied Linguistics, Identity and Power and Language Use in Professional Contexts, the "Reader" takes a broad interpretation of the subject…

  16. Modelling and numerical simulation of liquid-vapor phase transitions; Modelisation et simulation numerique des transitions de phase liquide-vapeur

    Energy Technology Data Exchange (ETDEWEB)

    Caro, F


    This work deals with the modelling and numerical simulation of liquid-vapor phase transition phenomena. The study is divided into two part: first we investigate phase transition phenomena with a Van Der Waals equation of state (non monotonic equation of state), then we adopt an alternative approach with two equations of state. In the first part, we study the classical viscous criteria for selecting weak solutions of the system used when the equation of state is non monotonic. Those criteria do not select physical solutions and therefore we focus a more recent criterion: the visco-capillary criterion. We use this criterion to exactly solve the Riemann problem (which imposes solving an algebraic scalar non linear equation). Unfortunately, this step is quite costly in term of CPU which prevent from using this method as a ground for building Godunov solvers. That is why we propose an alternative approach two equations of state. Using the least action principle, we propose a phase changing two-phase flow model which is based on the second thermodynamic principle. We shall then describe two equilibrium submodels issued from the relaxations processes when instantaneous equilibrium is assumed. Despite the weak hyperbolicity of the last sub-model, we propose stable numerical schemes based on a two-step strategy involving a convective step followed by a relaxation step. We show the ability of the system to simulate vapor bubbles nucleation. (author)

  17. Hybrid meshes and domain decomposition for the modeling of oil reservoirs; Maillages hybrides et decomposition de domaine pour la modelisation des reservoirs petroliers

    Energy Technology Data Exchange (ETDEWEB)

    Gaiffe, St.


    In this thesis, we are interested in the modeling of fluid flow through porous media with 2-D and 3-D unstructured meshes, and in the use of domain decomposition methods. The behavior of flow through porous media is strongly influenced by heterogeneities: either large-scale lithological discontinuities or quite localized phenomena such as fluid flow in the neighbourhood of wells. In these two typical cases, an accurate consideration of the singularities requires the use of adapted meshes. After having shown the limits of classic meshes we present the future prospects offered by hybrid and flexible meshes. Next, we consider the generalization possibilities of the numerical schemes traditionally used in reservoir simulation and we draw two available approaches: mixed finite elements and U-finite volumes. The investigated phenomena being also characterized by different time-scales, special treatments in terms of time discretization on various parts of the domain are required. We think that the combination of domain decomposition methods with operator splitting techniques may provide a promising approach to obtain high flexibility for a local tune-steps management. Consequently, we develop a new numerical scheme for linear parabolic equations which allows to get a higher flexibility in the local space and time steps management. To conclude, a priori estimates and error estimates on the two variables of interest, namely the pressure and the velocity are proposed. (author)

  18. Adsorption of trace elements on a bentonite sample: experimental study and modelling; Retention d'elements trace sur une bentonite: etude experimentale et modelisation

    Energy Technology Data Exchange (ETDEWEB)

    Hurel, Ch


    Radioactive waste storage in deep underground is studied in France. The alteration of the radioactive waste can mobilize the elements that can migrate to the geosphere. Clays (bentonite) are investigated as major materials constituting the barriers because of their low permeability and high retention capacity. A thermodynamic surface complexation model, based on the component additivity principle was investigated, in order to predict the adsorption behaviour of pollutants in contact with clay. This principle allows an independent determination of each parameter of the model, limiting the fitting procedure of correlated data, and it allows the use of an adsorption thermodynamic database for a solid. The predictions obtained were in good accordance with experimental data. The model could then be applied successfully in performance assessment. (author)

  19. Developpement energetique par modelisation et intelligence territoriale: Un outil de prise de decision participative pour le developpement durable des projets eoliens (United States)

    Vazquez Rascon, Maria de Lourdes

    This thesis focuses on the implementation of a participatory and transparent decision making tool about the wind farm projects. This tool is based on an (argumentative) framework that reflects the stakeholder's values systems involved in these projects and it employs two multicriteria methods: the multicriteria decision aide and the participatory geographical information systems, making it possible to represent this value systems by criteria and indicators to be evaluated. The stakeholder's values systems will allow the inclusion of environmental, economic and social-cultural aspects of wind energy projects and, thus, a sustainable development wind projects vision. This vision will be analyzed using the 16 sustainable principles included in the Quebec's Sustainable Development Act. Four specific objectives have been instrumented to favor a logical completion work, and to ensure the development of a successfultool : designing a methodology to couple the MCDA and participatory GIS, testing the developed methodology by a case study, making a robustness analysis to address strategic issues and analyzing the strengths, weaknesses, opportunities and threads of the developed methodology. Achieving the first goal allowed us to obtain a decision-making tool called Territorial Intelligence Modeling for Energy Development (TIMED approach). The TIMED approach is visually represented by a figure expressing the idea of a co-construction decision and where ail stakeholders are the focus of this methodology. TIMED is composed of four modules: Multi-Criteria decision analysis, participatory geographic Information systems, active involvement of the stakeholders and scientific knowledge/local knowledge. The integration of these four modules allows for the analysis of different implementation scenarios of wind turbines in order to choose the best one based on a participatory and transparent decision-making process that takes into account stakeholders' concerns. The second objective

  20. Thermal stability of the French nuclear waste glass - long term behavior modeling; Etude de la stabilite thermique du verre nucleaire. Modelisation de son evolution a long terme

    Energy Technology Data Exchange (ETDEWEB)

    Orlhac, X


    The thermal stability of the French nuclear waste glass was investigated experimentally and by modeling to predict its long-term evolution at low temperature. The crystallization mechanisms were analyzed by studying devitrification in the supercooled liquid. Three main crystalline phases were characterized (CaMoO{sub 4}, CeCO{sub 2}, ZnCr{sub 2}O{sub 4}). Their crystallisation was TO 4.24 wt%, due to the low concentration of the constituent elements. The nucleation and growth curves showed that platinoid elements catalysed nucleation but did not affect growth, which was governed by volume diffusion. The criteria of classic nucleation theory were applied to determine the thermodynamic and diffusional activation energies. Viscosity measurements illustrate the analogy between the activation energy of viscous flow and diffusion, indicating control of crystallization by viscous flow phenomena. The combined action of nucleation and growth was assessed by TTT plots, revealing a crystallization equilibrium line that enables the crystallized fractions to be predicted over the long term. The authors show that hetero-genetics catalyze the transformation without modifying the maximum crystallized fraction. A kinetic model was developed to describe devitrification in the glass based on the nucleation and growth curves alone. The authors show that the low-temperature growth exhibits scale behavior (between time and temperature) similar to thermo-rheological simplicity. The analogy between the resulting activation energy and that of the viscosity was used to model growth on the basis of viscosity. After validation with a simplified (BaO{sub 2}SiO{sub 2}) glass, the model was applied to the containment glass. The result indicated that the glass remained completely vitreous after a cooling scenario with the one measured at the glass core. Under isothermal conditions, several million years would be required to reach the maximum theoretical crystallization fraction. (author)