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Sample records for application possibilities novye

  1. Enzymes: The possibility of production and applications

    Directory of Open Access Journals (Sweden)

    Petronijević Živomir B.

    2003-01-01

    Full Text Available Enzymes are biological catalysts with increasing application in the food pharmaceutical, cosmetic, textile and chemical industry. They are also important as reagents in chemical analysis, leather fabrications and as targets for the design of new drugs. Keeping in mind the growing need to replace classical chemical processes by alternative ones, because of ever growing environmental pollution, it is important that enzyme and other biotechnological processes are economical. Therefore, price decrease and stability and enzyme preparation efficiency increase are required more and more. This paper presents a short review of methods for yield increase and the improvement of the quality of enzyme products as commercial products, as well as a review of the possibilities of their application.

  2. POSSIBLE RECESSION CURVE APPLICATIONS FOR RETENTION EVALUATION

    Directory of Open Access Journals (Sweden)

    Daniel Liberacki

    2015-11-01

    Full Text Available The objective of the article was to present possible applications of recession flow curve in a small lowland watershed retention discharge size evaluation. The examined woodland micro catchment area of 0.52 sq km is located in Puszcza Zielonka in central Wielkopolska. The Hutka catchment is typically woody with high retention abilities. The catchment of the Hutka watercourse is forested in 89%, the other 11% is covered by swamps and wasteland. The predominant sites are fresh mixed coniferous forest (BMśw, fresh coniferous forest (Bśw and alder carr forest (Ol. Landscape in catchment is characterized by a large number of interior depressions, filled partly with rainwater or peatbogs, with poorly developed natural drainage. The watercourses do not exceed 1 km in length, the mean width is approx. 0.5 m, while mean depth ranges from 0.2 to 0.3 m. During hydrological research conducted in 1997/1998–1999/2000, 35 major (characteristic raised water stages were observed in Hutka after substantial precipitation. The recession curve dating from 18–24 September 2000 has the α and n rates nearest to average. Comparing the model curve and the curve created by observing watercourse flow, one can notice their resemblance and that they have similar ordinate values as well as shape. In the case of other recession curves, the maximum differences of ordinate values are also about 0.1–0.2 l/s/km2. The measuured α and n rates do not reveal any regularities. There are no significant statistical Horton model parameter (for recession flow curves dependencies between α and n and e.g. initial flows (Qo or the whole period of high water waves (Qp. Consequently, calculated relation between these parameters is only an approximation for the general evaluation of the retention discharge in the catchment area towards retention with flow function.

  3. Ceramics in Environmental Catalysis:Applications and Possibilities%Ceramics in Environmental Catalysis: Applications and Possibilities

    Institute of Scientific and Technical Information of China (English)

    Nitin LABHSETWAR; P.DOGGALI; S.RAYALU; R.YADAV; T.MISTUHASHI; H.HANEDA

    2012-01-01

    Environmental catalysis has been steadily growing because of the advances in its scientific and engineering aspects,as well as due to the new environmental challenges in the industrial era.The development of new catalysts and materials is essential for new technologies for various environmental applications.Ceramics play important roles in various environmental applications including the identification,monitoring,and quantification of pollutants and their control.Ceramics have important applications as sensors and photocatalysts,and they are extensively used as catalyst carriers and supports.Many ceramics are being explored as catalysts for pollution control applications.Their low cost,thermal and chemical stability,and capability of being tailored make them especially attractive for pollution control applications.Although a wide variety of materials have been developed as catalyst supports,this area is still of interest with new or modified catalyst supports being frequently reported.It is of equal importance to develop new or modified processes for the loading of catalysts on specific supports.Applications like chemical looping combustion (CLC) and other catalytic combustion processes are raising the demands to a new scale.We have been working on the development of both new and modified support materials,including mesoporous materials without structural order for possible applications in CLC and other catalytic reactions.Successful attempts have been made in the modification of conventional γ-Al2O3 and improved synthesis processes for supporting perovskite type catalysts.Our research on environmental catalysis applications of ceramic materials and processes are also briefly discussed.

  4. Electrical conduction in solid materials physicochemical bases and possible applications

    CERN Document Server

    Suchet, J P

    2013-01-01

    Electrical Conduction in Solid Materials (Physicochemical Bases and Possible Applications) investigates the physicochemical bases and possible applications of electrical conduction in solid materials, with emphasis on conductors, semiconductors, and insulators. Topics range from the interatomic bonds of conductors to the effective atomic charge in conventional semiconductors and magnetic transitions in switching semiconductors. Comprised of 10 chapters, this volume begins with a description of electrical conduction in conductors and semiconductors, metals and alloys, as well as interatomic bon

  5. Coherent X-ray mirage: discovery and possible applications

    Institute of Scientific and Technical Information of China (English)

    Tatiana; Pikuz; Anatoly; Faenov; Sergey; Magnitskiy; Nikolay; Nagorskiy; Momoko; Tanaka; Masahiko; Ishino; Masaharu; Nishikino; Yuji; Fukuda; Masaki; Kando; Yoshiaki; Kato; Tetsuya; Kawachi

    2014-01-01

    In the far field of the intensity distribution of the beam delivered by a two-stage transient–collisional excitation X-ray laser(XRL), a non-expected interference pattern that is stable from shot to shot has been discovered. It is demonstrated that the interference is caused by the emergence of an imaginary source in the amplifying plasma, which is phase matched to the radiation of the generator. The observed phenomenon is called an X-ray coherent mirage. To explain the obtained results, a new theoretical approach is developed. The basic essential conditions for formation of the X-ray mirage are formulated, and possible applications are discussed. This paper details the experiments, including the formulation of the necessary and sufficient conditions for formation of the X-ray mirage, and possible applications are discussed.

  6. Social Constructionist Psychology and its Application. Possibilities for a Reorientation

    Directory of Open Access Journals (Sweden)

    Johannes von Tiling

    2008-01-01

    Full Text Available Social constructionism currently is understood as a metatheoretical alternative to positivism. It serves many social and cultural scientists as a point of reference. The possibilities to understand it as a psychological program of research that leaves space for agency and subjectivity usually are neglected. Promoting a dialogue with mainstream psychology constitutes one way of fostering social constructionist psychology. In addition, a theoretically productive conception of social constructionist psychology cannot do without reference to cultural psychology. An important advantage of such a conception lies in the increased number of possibilities for practical applications in hospitals, schools and factories. Whereas present applications of social constructionism tend to promote the postmodernization and individualization of the client, applied social constructionist psychology avoids these concomitant effects. URN: urn:nbn:de:0114-fqs0801446

  7. [Application possibilities of chemical imaging in pharmaceutical technology].

    Science.gov (United States)

    Vajna, Balázs; Nagy, Zsombor; Patyi, Gergo; Zsigmond, Zsolt; Antal, István; Marosi, György

    2009-01-01

    Chemical imaging is a novel analytical method that simultaneously delivers spatial, chemical, structural, and functional information on the dosage forms. Both infrared and Raman spectroscopic imaging may serve as useful nondestructive analytical techniques in the pharmaceutical product development and quality control. Most important application possibilities are reviewed and some studies demonstrate the advantages of the structure exploration. Raman imaging is suitable to understand and control the quality attributes of different dosage forms.

  8. Present and possible future applications of superhard nanocomposite coatings

    Energy Technology Data Exchange (ETDEWEB)

    Holubar, P.; Jilek, M.; Sima, M. [SHM, Ltd., Sumperk (Czech Republic)

    2000-11-01

    Recent investigations into the multicomponent (TiAlSi)N and TiBN superhard coatings revealed that the nanostructure, properties and deposition conditions needed for their preparation are in agreement with the known generic concept for the design of novel superhard nanocomposites due to thermodynamically driven phase segregation. All coatings to be reported here were developed on a production scale plasma PVD and CVD equipment consisting of vacuum arc evaporation from a central cathode for the metals in combination with PCVD of non-metals, such as boron, from gaseous reactant. Depending on the composition and deposition conditions the hardness of the coatings is controlled in the range between 35 and 45 GPa or higher. However, for the majority of applications the highest hardness is not the primary goal. More important is the appropriate combination of high hardness with other properties, such as fracture toughness, oxidation resistance, adhesion, etc. The effect of these properties on the resulting utility value of the coated tools will be discussed with respect to the available cutting tools made of cemented carbide and coated with the nanocomposites. Presently, dry milling, drilling and possibly turning are the most important applications of such coated tools. In view of the fairly fast transition from the initial development of these coatings towards their industrial production many further applications are expected. Therefore, future possibilities will be discussed as well. (orig.)

  9. Possible application of brewer’s spent grain in biotechnology

    Directory of Open Access Journals (Sweden)

    Pejin Jelena D.

    2013-01-01

    Full Text Available Brewer’s spent grain is the major by-product in beer production. It is produced in large quantities (20 kg per 100 liters of produced beer throughout the year at a low cost or no cost, and due to its high protein and carbohydrates content it can be used as a raw material in biotechnology. Biotechnological processes based on renewable agro-industrial by-products have ecological (zero CO2 emission, eco-friendly by-products and economical (cheap raw materials and reduction of storage costs advantages. The use of brewer’s spent grain is still limited, being basically used as animal feed. Researchers are trying to improve the application of brewer’s spent grain by finding alternative uses apart from the current general use as an animal feed. Its possible applications are in human nutrition, as a raw material in biotechnology, energy production, charcoal production, paper manufacture, as a brick component, and adsorbent. In biotechnology brewer’s spent grain could be used as a substrate for cultivation of microorganisms and enzyme production, additive of yeast carrier in beer fermentation, raw material in production of lactic acid, bioethanol, biogas, phenolic acids, xylitol, and pullulan. Some possible applications for brewer’s spent grain are described in this article including pre-treatment conditions (different procedures for polysaccharides, hemicelluloses, and cellulose hydrolysis, working microorganisms, fermentation parameters and obtained yields. The chemical composition of brewer’s spent grain varies according to barley variety, harvesting time, malting and mashing conditions, and a quality and type of unmalted raw material used in beer production. Brewer’s spent grain is lignocellulosic material rich in protein and fibre, which account for approximately 20 and 70% of its composition, respectively.

  10. Possible applications of clinoptilolites for natural water purification

    Directory of Open Access Journals (Sweden)

    N.I. Vatin

    2013-03-01

    Full Text Available Possible applications of clinoptilolites (CP in natural water purification processes from various contaminants are evaluated. Sorption properties of CP in various deposits of Russia are studied in relation to heavy metal ions. It was found that the studied specimens have a considerable sorption exchange capacity not only for ions of toxic (Hg2+, Cd2+, Pb2', but also other heavy metals (Cu2+, Co2+, Ni2+, Zn2+, Ba2+ , Sr2+. It is shown that CP sorption capacity is more efficient when a Mn2+ ion is removed from natural water compared to synthetic ion-exchange resins and activated coals. The dynamic sorption capacities for a Mn2+ ion up to a breakthrough 0.01 mg/1 and 0.1 mg/1 is determined. The CP sorption capacity is insignificant for various halide ions except a fluoride ion the removal of which from natural underground waters is possible with the help of sorption on CP. It was proposed to use CP for removing natural radionuclides (radium 226 and potassium 40 from deep wellbore waters. The purification efficiency with the initial radium 226 concentration at the level 3,0 Bq/I (30 MPC was not below 96%. The efficiency of removing potassium 40 natural isotope depends on the CP form and is maximal for Na form. Post treatment of natural waters after their coagulation treatment with the use of CP has been studied. It is shown that sorption filters with CP allow not only post-treatment of waters from excessive aluminum and zinc, but also additional reduction of odor, color, and ammonium ion content.

  11. Possibilities of contactless control of web map applications by sight

    Directory of Open Access Journals (Sweden)

    Rostislav Netek

    2012-03-01

    Full Text Available This paper assesses possibilities of a new approach of control map applications on the screen without locomotive system. There is a project about usability of Eye Tracking System in Geoinformatic and Cartographic fields at Department of Geoinformatics at Palacky University. The eye tracking system is a device for measuring eye/gaze positions and eye/gaze movement ("where we are looking". There is a number of methods and outputs, but the most common are "heat-maps" of intensity and/or time. Just this method was used in the first part, where was analyzed the number of common web map portals, especially distribution of their tools and functions on the screen. The aim of research is to localize by heat-maps the best distribution of control tools for movement with map (function "pan". It can analyze how sensitive are people on perception of control tools in different web pages and platforms. It is a great experience to compare accurate survey data with personal interpretation and knowledge. Based on these results is the next step – design of "control tools" which is command by eye-tracking device. There has been elected rectangle areas located on the edge of map (AOI – areas of interest, with special function which have defined some time delay. When user localizes one of these areas the map automatically moves to the way on which edge is localized on, and time delay prevents accidental movement. The technology for recording the eye movements on the screen offers this option because if you properly define the layout and function controls of the map, you need only connect these two systems. At this moment, there is a technical constrain. The solution of movement control is based on data transmission between eye-tracking-device-output and converter in real-time. Just real-time transfer is not supported in every case of SMI (SensoMotoric Instruments company devices. More precisely it is the problem of money, because eye-tracking device and every

  12. Review on thin-film transistor technology, its applications, and possible new applications to biological cells

    Science.gov (United States)

    Tixier-Mita, Agnès; Ihida, Satoshi; Ségard, Bertrand-David; Cathcart, Grant A.; Takahashi, Takuya; Fujita, Hiroyuki; Toshiyoshi, Hiroshi

    2016-04-01

    This paper presents a review on state-of-the-art of thin-film transistor (TFT) technology and its wide range of applications, not only in liquid crystal displays (TFT-LCDs), but also in sensing devices. The history of the evolution of the technology is first given. Then the standard applications of TFT-LCDs, and X-ray detectors, followed by state-of-the-art applications in the field of chemical and biochemical sensing are presented. TFT technology allows the fabrication of dense arrays of independent and transparent microelectrodes on large glass substrates. The potential of these devices as electrical substrates for biological cell applications is then described. The possibility of using TFT array substrates as new tools for electrical experiments on biological cells has been investigated for the first time by our group. Dielectrophoresis experiments and impedance measurements on yeast cells are presented here. Their promising results open the door towards new applications of TFT technology.

  13. Stable atomic hydrogen possible application in intense polarized sources

    CERN Document Server

    Niinikoski, T O; Rieubland, Jean Michel

    1982-01-01

    The authors briefly review the status of spin-polarized atomic hydrogen and discuss a possible way of extending the present limit of density. Pulse extraction of stabilized atoms by millimetre wave is proposed as a means of producing polarized atomic beams of uniform velocity and low divergence. It is speculated that these atoms could be used either as jet targets of a conventional type, or as a stored atomic beam target by injecting them into a storage ring intersecting with an accelerator beam. When used in a polarized ion source, the high density of the atomic beam could possibly also improve the ionizer efficiency.

  14. Synthesis and biomedical applications of aerogels: Possibilities and challenges.

    Science.gov (United States)

    Maleki, Hajar; Durães, Luisa; García-González, Carlos A; Del Gaudio, Pasquale; Portugal, António; Mahmoudi, Morteza

    2016-10-01

    Aerogels are an exceptional group of nanoporous materials with outstanding physicochemical properties. Due to their unique physical, chemical, and mechanical properties, aerogels are recognized as promising candidates for diverse applications including, thermal insulation, catalysis, environmental cleaning up, chemical sensors, acoustic transducers, energy storage devices, metal casting molds and water repellant coatings. Here, we have provided a comprehensive overview on the synthesis, processing and drying methods of the mostly investigated types of aerogels used in the biological and biomedical contexts, including silica aerogels, silica-polymer composites, polymeric and biopolymer aerogels. In addition, the very recent challenges on these aerogels with regard to their applicability in biomedical field as well as for personalized medicine applications are considered and explained in detail.

  15. Log-periodicity: Sources, characterization, identification, and possible applications

    Science.gov (United States)

    Huang, Yueqiang

    1999-11-01

    We investigate theoretically the log-periodic oscillations that have recently been observed in several rupture processes ranging from earthquakes to financial crashes. A possible source of log-periodic oscillations is an underlying discrete scale invariance (DSI). The first chapter of this dissertation is devoted to understanding how DSI could appear spontaneously in a physical system. We consider the example of crack arrays, and argue that the short-wavelength Mullins-Sekerka instability, together with strong screening effects, could indeed generate DSI. This is backed by extensive numerical simulations, as well as some experimental observations. In the second chapter of this dissertation, we study in more details how DSI at the geometrical level can give rise to log-periodic oscillations in a rupture process: to do so, we explore in details a simple cellular automaton model of earthquakes on a fractal lattice and show how the divergence of the correlation length, combined with the fractal geometrical structure, determines the log-periodic oscillations. Despite its simplicity, we demonstrate that our model reproduces remarkably well the statistical aspects of earthquakes, in contrast with original, erroneous conclusions of early works on the matter. The key issue here is the interplay of self-organized criticality, finite size effects, and dissipation. Besides DSI, we point out that there are other possible sources of log-periodicity arising from data analysis. We discuss in considerable details the effects of noise integration in power laws. We point out that this mechanism calls for a re-examination of the interpretation of many previously observed log-periodic oscillations. We re-visit two early observations, the Loma Prieta case and the Kobe case, and unfortunately find that the observed log-periodic oscillations are not as significant as originally claimed. Finally, this dissertation also contains an important observational part in which we analyze in details

  16. Physiology, biochemistry and possible applications of microbial caffeine degradation.

    Science.gov (United States)

    Gummadi, Sathyanarayana N; Bhavya, B; Ashok, Nandhini

    2012-01-01

    Caffeine, a purine alkaloid is a constituent of widely consumed beverages. The scientific evidence which has proved the harm of this alkaloid has paved the way for innumerable research in the area of caffeine degradation. In addition to this, the fact that the by-products of the coffee and tea industry pollute the environment has called for the need of decaffeinating coffee and tea industry's by-products. Though physical and chemical methods for decaffeination are available, the lack of specificity for removal of caffeine in these techniques and their non-eco-friendly nature has opened the area of microbial and enzymatic degradation of caffeine. Another important application of microbial caffeine degradation apart from its advantages like specificity, eco-friendliness and cost-effectiveness is the fact that this process will enable the production of industrially and medically useful components of the caffeine degradation pathway like theobromine and theophylline. This is a comprehensive review which mainly focuses on caffeine degradation, large-scale degradation of the same and its applications in the industrial world.

  17. A possible application of magnetic resonance imaging for pharmaceutical research.

    Science.gov (United States)

    Kowalczuk, Joanna; Tritt-Goc, Jadwiga

    2011-03-18

    Magnetic resonance imaging (MRI) is a non-destructive and non-invasive method, the experiment can be conducted in situ and allows the studying of the sample and the different processes in vitro or in vivo. 1D, 2D or 3D imaging can be undertaken. MRI is nowadays most widely used in medicine as a clinical diagnostic tool, but has still seen limited application in the food and pharmaceutical sciences. The different imaging pulse sequences of MRI allow to image the processes that take place in a wide scale range from ms (dissolution of compact tablets) to hours (hydration of drug delivery systems) for mobile as well as for rigid spins, usually protons. The paper gives examples of MRI application of in vitro imaging of pharmaceutical dosage based on hydroxypropyl methylcellulose which have focused on water-penetration, diffusion, polymer swelling, and drug release, characterized with respect to other physical parameters such as pH and the molecular weight of polymer. Tetracycline hydrochloride was used as a model drug. NMR imaging of density distributions and fast kinetics of the dissolution behavior of compact tablets is presented for paracetamol tablets.

  18. Possibilities of thermovision application in sport and sport rehabilitation

    Directory of Open Access Journals (Sweden)

    Badža Vukašin

    2012-01-01

    Full Text Available Introduction. Infrared thermography or thermovision is increasingly applicable in sport and sport rehabilitation. Thermic forms, thermic imprints, temperature and isotherm distribution, temperature gradient change are the terms that are more and more often met in sport medicine and medicine, in general. Case report. We presented two examples of thermovision application: in detection of muscle injury and changes of the feet exposed to low temperature. In the first example the thermovision method was used for analyzing heat distribution in an athlete with back muscles injury. With a special original method of local cooling the place and degree of injury was precisely localized and determined, respectively, regardless high environmental temperature. In the second case the thermovision method was for the first time applied in a runner whose feet was exposed to low temperature. Significant hypothermia of the feet was detected by the method and appropriate treatment was performed. Thanks to this the athlete had no harmful consequences. Conclusion. Thermovision is fast and efficient in detecting different kind of injuries, so its increased use in the future can be expected.

  19. Possibilities of computer application in modern geography teaching process

    Directory of Open Access Journals (Sweden)

    Ivkov-Džigurski Anđelija

    2009-01-01

    Full Text Available Geography is a science that follows modern trends in the development of contemporary science. One of the crucial things that gives teaching process a high quality in the application of modern techniques and methods. Modern organization of the teaching process in primary and secondary schools is unimaginable without innovations. This would mean changes and new elements in all segments of the teaching process. Good organization, innovation and new tendencies in the development of the science can raise the quality of the teaching process, thus enabling the student to study fully and rationally. Innovations should help students develop a dialectic way of thinking when explaining objects, phenomena and processes in nature and society, as well as enable them to notice cause and effect relationships. The application of new methods should provide maximum activity of the students in terms of their research and independent work. Computers are used in many different ways therefore they can be used very rationally in different segments of the teaching process.

  20. The possibilities of application of GIS in landscape planning

    Directory of Open Access Journals (Sweden)

    Janez Marušič

    1992-12-01

    Full Text Available The application of GIS technologg in Slovenian landscape planning practice goes back to the beginning of the 70-ties when earlg types of GIS programs have been introduced to the countrg. They have been used within the environmental impact studies and land use planning projects and graduallg adapted to the particularities of Slovenian planning practice. The paper represents some types of data processing that have been applied in various planning projects. The type of data processing uiithin the GIS technology is defined by a model that should be based on generalized expert knowledge. There are several types of models for data processing within the landscape planning process: (1 representation models, (2 models for analysis or research models, (3 simulation models, (4 evaluation models, (5 models for synthesis, and (5 decision models.

  1. Models to Study NK Cell Biology and Possible Clinical Application.

    Science.gov (United States)

    Zamora, Anthony E; Grossenbacher, Steven K; Aguilar, Ethan G; Murphy, William J

    2015-08-03

    Natural killer (NK) cells are large granular lymphocytes of the innate immune system, responsible for direct targeting and killing of both virally infected and transformed cells. NK cells rapidly recognize and respond to abnormal cells in the absence of prior sensitization due to their wide array of germline-encoded inhibitory and activating receptors, which differs from the receptor diversity found in B and T lymphocytes that is due to the use of recombination-activation gene (RAG) enzymes. Although NK cells have traditionally been described as natural killers that provide a first line of defense prior to the induction of adaptive immunity, a more complex view of NK cells is beginning to emerge, indicating they may also function in various immunoregulatory roles and have the capacity to shape adaptive immune responses. With the growing appreciation for the diverse functions of NK cells, and recent technological advancements that allow for a more in-depth understanding of NK cell biology, we can now begin to explore new ways to manipulate NK cells to increase their clinical utility. In this overview unit, we introduce the reader to various aspects of NK cell biology by reviewing topics ranging from NK cell diversity and function, mouse models, and the roles of NK cells in health and disease, to potential clinical applications. © 2015 by John Wiley & Sons, Inc.

  2. "Smart" polymeric nanospheres as new materials for possible biomedical applications.

    Science.gov (United States)

    Szczubiałka, Krzysztof; Jankowska, Monika; Nowakowska, Maria

    2003-08-01

    Novel random terpolymers of N-isopropylacrylamide (NIPAM), sodium 2-acrylamido-2-methyl-1-propanesulfonate (AMPS), and cinnamoyloxyethylmethacrylate (CEMA) were synthesized by free radical copolymerization using AIBN as an initiator. Five terpolymers were obtained by copolymerization of the monomer mixtures containing a fixed amount of 10 mol % of AMPS while the content of CEMA ranged from 5 to 25 mol % and was changed in 5 mol % increments. The terpolymers obtained are water-soluble. Because of their amphiphilic nature they undergo self-organization in the aqueous solution with the formation of micelles capable of solubilizing sparingly water soluble organic compounds, such as drugs. The terpolymers are susceptible to three external stimuli, i.e. temperature, ionic strength and UV light. Due to the presence of NIPAM in the terpolymers they display the lower critical solution temperature (LCST), the presence of AMPS makes them sensitive to the ionic strength of the solution, while the light-responsiveness of the terpolymers is due to the presence of cinnamoyl chromophores, which undergo photodimerization when irradiated with UV light at about 280 nm. Application of any of these stimuli alone or in combination with other stimuli allows changing the copolymer properties in a controlled way.

  3. Advanced multiresponsive comploids: from design to possible applications

    Science.gov (United States)

    Crassous, Jérôme J.; Mihut, Adriana M.; Dietsch, Hervé; Pravaz, Olivier; Ackermann-Hirschi, Liliane; Hirt, Ann M.; Schurtenberger, Peter

    2014-07-01

    We extend the commonly used synthesis strategies for responsive microgels to the design of novel multiresponsive and multifunctional nanoparticles that combine inorganic magnetic, metallic/catalytic and thermoresponsive organic moieties. Magnetic responsiveness is implemented through the integration of silica-coated maghemite nanoparticles into fluorescently labeled crosslinked poly(N-isopropylmethacrylamide) microgels. These particles are then employed as templates for the in situ reduction of catalytically active gold nanoparticles. In order to tune the reactivity of the catalyst through a thermally controlled barrier, an additional layer of crosslinked poly(N-isopropylacrylamide) is added in the final step. We subsequently demonstrate that these particles can be employed as smart catalysts. We show that the thermoresponsive nature of the outer particle shell not only provides control over the catalytic activity, but when combined with a magnetic core allows for very efficient removal of the catalytic system through temperature-controlled reversible coagulation and subsequent magnetophoresis in an applied magnetic field gradient. We finally discuss the use of this design principle for the synthesis of complex hybrid particles for various applications that would all profit from their multiresponsive and multifunctional nature.We extend the commonly used synthesis strategies for responsive microgels to the design of novel multiresponsive and multifunctional nanoparticles that combine inorganic magnetic, metallic/catalytic and thermoresponsive organic moieties. Magnetic responsiveness is implemented through the integration of silica-coated maghemite nanoparticles into fluorescently labeled crosslinked poly(N-isopropylmethacrylamide) microgels. These particles are then employed as templates for the in situ reduction of catalytically active gold nanoparticles. In order to tune the reactivity of the catalyst through a thermally controlled barrier, an additional layer

  4. The analysis of the possibility of the application of the casting waxes in the process RP

    OpenAIRE

    G. Budzik

    2009-01-01

    The article presents analysis of possibility of application of casting waxes in process of rapid prototyping of casting models in silicone the matrices. The researches were made on casting waxes applied to the manufacturing of precise casting models and also the model system. Testing waxes are intended nominally to the processing in process of the injection. The determining of possibility processing of waxes in silicone forms was purpose of researches. Researches concerned of whole manufactur...

  5. A Review on Current and Emerging Application Possibilities for Unmanned Aerial Vehicles

    OpenAIRE

    Beloev Ivan H.

    2016-01-01

    This paper presents a review on current and emerging application possibilities for unmanned aerial vehicles (UAVs). The introduction section of the paper briefly describes some of the application areas in which drones are currently being used. The next chapters of the paper describe more detailly the use of UAVs for aerial photography, filming, security and logistics, GIS, land and water surveys. The main focus of the last chapters is on the advantages and the disadvantages of the drones usag...

  6. Novye ateisticheskie podkhody v kognitivnoi nauke o religii

    DEFF Research Database (Denmark)

    Geertz, Armin W.

    2013-01-01

    En russisk oversættelse af et kapitel i bogen Contemporary Theories of Religion: A Critical Companion, red. af Michael Stausberg (Abingdon: Routledge, 2009) på engelsk. Det russiske tidsskrift har titlen State, Religion and Church in Russia and Worldwide....

  7. Basic Structure of Some Classes of Neutrosophic Crisp Nearly Open Sets & Possible Application to GIS Topology

    Directory of Open Access Journals (Sweden)

    A. A. Salama

    2015-01-01

    Full Text Available Since the world is full of indeterminacy, the neutrosophics found their place into contemporary research. The fundamental concepts of neutrosophic set, introduced by Smarandache and Salama et al. In Geographical information systems (GIS there is a need to model spatial regions with indeterminate boundary and under indeterminacy. In this paper the structure of some classes of neutrosophic crisp nearly open sets are investigated and some applications are given. Finally we generalize the crisp topological and intuitioistic studies to the notion of neutrosophic crisp set. Possible applications to GIS topological rules are touched upon.

  8. A survey of possible passive antenna applications of high-temperature superconductors

    Science.gov (United States)

    Dinger, Robert J.; Bowling, Donald R.; Martin, Anna M.

    1991-09-01

    A survey of possible applications of high-temperature superconductors (HTSs) to antennas and antenna feed networks is presented. The frequency range considered is 1 MHz to 100 GHz. Three antenna application areas seem appropriate for HTS material: electrically small antennas and their matching networks; feed and matching networks for compact arrays with enhanced directive gain (superdirective arrays); and feed networks for millimeter-wave arrays. Preliminary experimental results are presented on YBaCuO and TBaCaCuO 500 MHz half-loop antennas that show an increase in radiation efficiency (compared with a copper antenna at the same temperature) by a factor of 5 for the HTS antennas.

  9. Possible applications of powerful pulsed CO{sub 2}-lasers in tokamak reactors

    Energy Technology Data Exchange (ETDEWEB)

    Nastoyashchii, A.F.; Morozov, I.N. [Troitsk Inst. for Innovation and Fusion Research, Moscow (Russian Federation); Hassanein, A. [Argonne National Lab., IL (United States)

    1998-08-01

    Applications of powerful pulsed CO{sub 2}-lasers for injection of fuel tablets or creation of a protective screen from the vapor of light elements to protect against the destruction of plasma-facing components are discussed, and the corresponding laser parameters are determined. The possibility of using CO{sub 2}-lasers in modeling the phenomena of powerful and energetic plasma fluxes interaction with a wall, as in the case of a plasma disruption, is considered.

  10. Sapropel as a Binder: Properties and Application Possibilities for Composite Materials

    Science.gov (United States)

    Obuka, V.; Šinka, M.; Kļaviņš, M.; Stankeviča, K.; Korjakins, A.

    2015-11-01

    Recent development trends largely look for possibilities of a wider use of natural materials and local resources. In this perspective, the use of organic rich lake sediment - sapropel - as a binding material in line with other environmentally friendly filling materials can be considered as a challenge. Sapropel itself is a valuable resource with multiple areas of application, for example, medicine, veterinary, agriculture, livestock farming, balneology, cosmetic applications, construction, and its application options have been widely studied in the 20th century in the Baltic countries, Ukraine and Russia. Birch wood fibre and sanding dust, hemp shives, ‘Aerosil’ are used as a filler and three types of sapropel are used as a binder in making composites. After material preparation and curing, physical and mechanical properties - density, thermal conductivity, compressive and flexural strength, were determined and compared to the data in the literature, and the opportunities to use them in the ecological construction were considered. The obtained results give insight into possibilities to use sapropel as a raw material, which can be considered as prospective material for construction materials and design products.

  11. A simple blackbody simulator with several possibilities and applications on thermography

    Science.gov (United States)

    dos Santos, Laerte; Lemos, Alisson Maria; Abi-Ramia, Marco Antônio

    2016-05-01

    Originally designed to make the practical examination on thermography certification1 possible, the device presented in this paper has demonstrated to be a very useful and versatile didactic tool for training centers and educational institutions, it can also be used as a low cost blackbody simulator to verify calibration of radiometers. It is a simple device with several functionalities for studying and for applications on heat transfer and radiometry, among them the interesting ability to thermally simulate the surface of real objects. On that functionality, if the device is seen by a thermographic camera, it reproduces the surface apparent temperatures of the object that it is simulating, at the same time, if it is seen by a naked eye it shows a visible image of that same surface. This functionality makes the practical study in the classroom possible, from different areas such as electrical, mechanical, medical, building, veterinary, etc.

  12. Harvesting Low-Frequency (Energy: A Possible Killer Application of Triboelectric Nanogenerator.

    Science.gov (United States)

    Zi, Yunlong; Guo, Hengyu; Wen, Zhen; Yeh, Min-Hsin; Hu, Chenguo; Wang, Zhong Lin

    2016-04-26

    Electromagnetic generators (EMGs) and triboelectric nanogenerators (TENGs) are the two most powerful approaches for harvesting ambient mechanical energy, but the effectiveness of each depends on the triggering frequency. Here, after systematically comparing the performances of EMGs and TENGs under low-frequency motion (harvested energy is wasted. In contrast, a TENG has an output voltage that is usually high enough (>10-100 V) and independent of frequency so that most of the generated power can be effectively used to power the devices. Furthermore, a TENG also has advantages of light weight, low cost, and easy scale up through advanced structure designs. All these merits verify the possible killer application of a TENG for harvesting energy at low frequency from motions such as human motions for powering small electronics and possibly ocean waves for large-scale blue energy.

  13. Gaseous Radiochemical Method for Registration of Ionizing Radiation and Its Possible Applications in Science and Industry

    CERN Document Server

    Lebedev, S G

    2005-01-01

    This work presents a new possibility of registration of ionizing radiation by the flowing gaseous radiochemical method (FGRM). The specified method uses the property of some solid crystalline lattice materials for a free emission of radioactive isotopes of inert gas atoms formed as a result of nuclear reactions. Generated in an ampoule of the detector, the radioactive inert gases are transported by a gas-carrier into the proportional gas counter of the flowing type, where the decay rate of the radioactive gas species is measured. This quantity is unequivocally related to the flux of particles (neutrons, protons, light and heavy ions) at the location of the ampoule. The method was used to monitor the neutron flux of the pulsed neutron target "RADEX" driven by the linear proton accelerator of INR RAS. Further progress of the FGRM may give rise to possible applications in nuclear physics, astrophysics and medicine, in the nondestructive control of fissionable materials, diagnostics of thermonuclear plasma, monit...

  14. Fourth-generation X-ray sources: some possible applications to biology.

    Science.gov (United States)

    Doniach, S

    2000-05-01

    The term 'fourth generation X-ray sources' has come to mean X-ray free-electron lasers which use multi-GeV electron beams from linear accelerators to generate X-rays by self-amplified stimulated emission when fired into long undulators. Properties of the radiation expected from such sources are reviewed briefly and two possible applications of the resulting pulsed highly collimated X-radiation to problems in biology are discussed: use of X-ray photon correlation spectroscopy to measure time correlations of atoms in protein crystals, and use of Mössbauer radiation extracted from the photon beams by resonant Bragg diffraction from (57)Fe-containing crystals, for MAD phasing of very large unit-cell biomolecular crystals and possibly for photon echo measurements.

  15. POSSIBILITIES OF APPLICATION OF INFORMATION TECHNOLOGIES IN EDUCATIONAL PRACTICE ON THE GENERAL PHYSICAL GEOGRAPHY

    Directory of Open Access Journals (Sweden)

    Mykola А. Fedoniuk

    2013-03-01

    Full Text Available The importance of use of information technologies during the training practices of geographical disciplines is shown. Some features of work with Google Earth and Stellarium software products are described. Examples of practical tasks for the students are given. In particular, such topics are considered: orienteering, determination of coordinates, of azimuths, work with photomap images, determining of the position and the apparent motion of celestial bodies, etc. Possible algorithms of work with services of archives of weather data are described. Prospects of further improvement of the organization of the educational practice of natural-study disciplines with application of information technologies are estimated.

  16. Possibilities of joining techniques application at railway lines joining and maintenance

    Directory of Open Access Journals (Sweden)

    I. Samardžić

    2011-10-01

    Full Text Available This paper presents most important techniques which is possible to apply at joining of railway lines as well as maintenance procedure. Beside thermit welding as a older joint process for that job (since 1895. it is mentioned flash welding as a modern joining technique interesting from the point of cost efficiency. In a case of maintance tasks it is necessary to caunt arc welding processes and thermit welding, too. Authors gave some experimental date collected during investigation on railway lines joining techniques application.

  17. NEURAL NETWORKS, FUZZY LOGIC AND GENETIC ALGORITHMS: APPLICATIONS AND POSSIBILITIES IN FINANCE AND ACCOUNTING

    Directory of Open Access Journals (Sweden)

    José Alonso Borba

    2010-04-01

    Full Text Available There are problems in Finance and Accounting that can not be easily solved by means of traditional techniques (e.g. bankruptcy prediction and strategies for investing in common stock. In these situations, it is possible to use methods of Artificial Intelligence. This paper analyzes empirical works published in international journals between 2000 and 2007 that present studies about the application of Neural Networks, Fuzzy Logic and Genetic Algorithms to problems in Finance and Accounting. The objective is to identify and quantify the relationships established between the available techniques and the problems studied by the researchers. Analyzing 258 papers, it was noticed that the most used technique is the Artificial Neural Network. The most researched applications are from the field of Finance, especially those related to stock exchanges (forecasting of common stock and indices prices.

  18. A Review on Current and Emerging Application Possibilities for Unmanned Aerial Vehicles

    Directory of Open Access Journals (Sweden)

    Beloev Ivan H.

    2016-09-01

    Full Text Available This paper presents a review on current and emerging application possibilities for unmanned aerial vehicles (UAVs. The introduction section of the paper briefly describes some of the application areas in which drones are currently being used. The next chapters of the paper describe more detailly the use of UAVs for aerial photography, filming, security and logistics, GIS, land and water surveys. The main focus of the last chapters is on the advantages and the disadvantages of the drones usage in precision agriculture, wildlife and nature observations and archaeology. The last chapters also provide information on how the advanced information technology solutions can be implemented in order to provide means for fighting invasive species, to increase the yield of certain crops, to monitor and predict flooding, wildfires and other disasters, etc. This paper provides only overview of the most interesting and widely available applications of the UAVs, but there are also many other more specific and dedicated solutions for implementation of the drones for different purposes.

  19. Preparation methodology and possible treatments for improved ceramics for high voltage vacuum applications

    CERN Document Server

    Tan, J

    1998-01-01

    The flashover characteristics of an insulator bridged high voltage vacuum gap can play an important role in the overall performance of a high voltage device, for example in the extreme environments of high energy particle accelerators. The detailed preparation of the insulators is, at present, governed by the commercial production methods and by standard bulk cleaning processes, which for a particular application may be far from optimum. The influence of the mechanical preparation, thermal history and particular cleaning technique have been investigated for commercially available alumina samples, with measurement of surface characteristics by scanning electron microscopy and laser diffraction, measurement of the secondary electron emission curve and analysis of the high voltage performance with the possibility of applied fields up to 200kV/cm. The results of the different measurements are discussed in the overall context of the problems encountered in the full sized high voltage devices, and suggestions are m...

  20. The focus group method and possibilities of its application in kinantropological research

    Directory of Open Access Journals (Sweden)

    Luděk Šebek

    2010-03-01

    Full Text Available In our article we deal with the problematics of focus groups and their implementation in kinantropological research. The primary target of an analysis of electronic information resources of the Palacky University was to look up research projects built upon the of focus group metodology. The analysis of accessible articles put forward that particularly in the field of kinantropological research, the method is used scarcely. The main objective of our article was to introduce the focus group as a valuable research method and outline the potential applications in kinantropology. On the basis of the summarized information on focus groups research we concluded that the focus groups may represent an effective tool for capturing such phenomenons as the affect of social environment, subcultural aspects, or self efficacy on development of attitudes to lifelong learning in the context of motor activity. The confirmation of the outlined possibilities will be the subject of our further research.

  1. Magnetic nanoparticles: an update of application for drug delivery and possible toxic effects.

    Science.gov (United States)

    Kim, Ji-Eun; Shin, Ji-Young; Cho, Myung-Haing

    2012-05-01

    Magnetic nanoparticles (MNPs) represent a subclass within the overall category of nanomaterials and are widely used in many applications, particularly in the biomedical sciences such as targeted delivery of drugs or genes, in magnetic resonance imaging, and in hyperthermia (treating tumors with heat). Although the potential benefits of MNPs are considerable, there is a distinct need to identify any potential toxicity associated with these MNPs. The potential of MNPs in drug delivery stems from the intrinsic properties of the magnetic core combined with their drug loading capability and the biomedical properties of MNPs generated by different surface coatings. These surface modifications alter the particokinetics and toxicity of MNPs by changing protein-MNP or cell-MNP interactions. This review contains current advances in MNPs for drug delivery and their possible organ toxicities associated with disturbance in body iron homeostasis. The importance of protein-MNP interactions and various safety considerations relating to MNP exposure are also addressed.

  2. Nonlinear Dynamics of Infectious Diseases Transfer with Possible Applications for Tubercular Infection

    CERN Document Server

    Krevchik, V D; Dahnovsky, Yu I; Semenov, M B; Shcherbakova, E V; Yamamoto, Kenji

    2007-01-01

    In this paper, we model a nonlinear dynamics of infectious diseases transfer. Particularly, we study possible applications to tubercular infection in models with different profiles (peak values) of the population density dependence on spatial coordinates. Our approach is based on the well known method of instantons which has been used by the authors to describe kinetics of adiabatic chemical reactions as a function of the heat-bath temperature and other system parameters. In our approach, we use "social temperature" T as one of the controlling parameters. Increase of T leads to acceleration of the infectious diseases transfer. The "blockage" effect for the infectious diseases transfer has been demonstrated in the case when peak values (in the population density) are equal to one and under condition that the "social temperature" is low. Existence of such effect essentially depends from environment "activity" (social and prophylactic). Results of our modeling qualitatively meet the tuberculosis dynamic spread d...

  3. The analysis of the possibility of the application of the casting waxes in the process RP

    Directory of Open Access Journals (Sweden)

    G. Budzik

    2009-04-01

    Full Text Available The article presents analysis of possibility of application of casting waxes in process of rapid prototyping of casting models in silicone the matrices. The researches were made on casting waxes applied to the manufacturing of precise casting models and also the model system. Testing waxes are intended nominally to the processing in process of the injection. The determining of possibility processing of waxes in silicone forms was purpose of researches. Researches concerned of whole manufacturing process i.e. the preparation of the form and wax, the filling of form and also the deforming. As a result of made researches the temperature of filling of matrix was determined. The main part of research process concerned determining of temperature of deforming for every with kinds of waxes. This is especially important in case of manufacturing of casting models of precise elements, which can be destroyed easily. In this purpose researches of the bending of waxen forms were made in the range of temperature 20-37ºC. The processing parameters of casting waxes were determined as a result of made researches.

  4. Possible applications of Neuromuscular Taping in pain reduction in Multiple Sclerosis subject: a preliminary report

    Directory of Open Access Journals (Sweden)

    Carmine Berlingieri

    2016-12-01

    Full Text Available Pain is a common disabling symptom in patients with Multiple Sclerosis (MS. It has been indicated that pain prevalence in MS patients is between 29–86 %. It is evident that most MS patients requiring treatment will be also searching pain related treatments to assist in day to day activities. Neuropathic pain is a difficult symptom and is generally inadequately relieved even though different rehabilitative approaches may be used. Neuromuscular Taping inducing micro-movements by stimulating receptors in the skin has been described in literature as a possible intervention in neurological and orthopedic rehabilitation improving mobility and in pain reduction. The aim of this preliminary report was to analyze the effect and to evaluate the possible applications of Neuromuscular Taping (NMT in patients with MS in order to reduce pain in comparison to the Transcutaneous Electrical Nerve Stimulation (TENS and to physical rehabilitation treatment alone. We observed that NMT together with standard physical rehabilitation was able to reduce neuropathic pain to greater lengths, with statistically significant differences between pre and post treatment, compared to the other treatments evaluated. This study showed increased efficacy in pain reduction when NMT was applied to standard physical treatment in long standing pain conditions. Neuromuscular Taping may constitute a low cost treatment strategy for neuropathic pain conditions in MS.

  5. The application of GIS for searching possible sources of pollution on the karst

    Directory of Open Access Journals (Sweden)

    Marko Krevs

    1992-12-01

    The waters on the karst normallg flow underground, except for some rare superficial waterflows on the fluviokarst. This is the reason to treat in a special way the presence of karst in the hinterland of a superficial waterflow. In such a čase GIS is a support to the deductive approach in solving the problem. Application of "karstic assumptions" about possible underground waterflow connections can substantiallg enlarge the area of possible locations of pollution sources beuond the borders of hgpsographic (superficial river basin. Three categories of areas endangering the water quality of the Otavščica brook have been derived from the data lagers, assumptions, and their interaction. They can serve us as a basis for the planning and execution of further actions to solve the problem. The appllcation is running on a portable PC. This enables its use in field work, including the search and registration of actual sources of pollution. In our study an area of 255 square kilometers (wider surroundings of Borovniški Pekel, southwest of Ljubljana has been taken into consideration.

  6. BUSINESS INTELLIGENCE APPLICATIONSPOSSIBLE INSTRUMENTS FOR ECONOMIC INTEGRATION WITHIN THE EASTERN PARTNERSHIP

    Directory of Open Access Journals (Sweden)

    Dragos Ovidiu TOFAN

    2016-10-01

    Full Text Available Eastern Partnership includes, in addition to bilateral components (Association Agreements, Deep and Comprehensive Free Trade Areas/DCFTA, also a multilateral dimension as "economic integration and convergence with EU policies". This stated purpose of the partnership involves the need for adaptability to regional conditions and a differentiated approach to economies in the region in order to establish common objectives. Partner countries have aspirations that vary by geographic location, state of relations with the European Union and Russia, foreign policy objectives in medium and long term, real prospects of joining the European Union, or internal stability in economic and social aspects. Macroeconomic indicators specific to each country must undergo a dynamic analysis aimed on current situations and also on evolution of economic life. Thus, it requires processing a huge volume of historical data, creating possible scenarios based on policies implemented or being implemented to reach comprehensive information to provide a realistic picture of the economic growth at the macro level. Successfully implemented in enterprises, Business Intelligence (BI applications can be used to analyze large volume of data required to be processed to reach full and useful reports for the process of negotiation between the partners involved in the agreements referred and, very importantly, to establish a common language for all bodies and institutions co-opted into negotiations. Differences between the EU and other Eastern Partnership countries are obvious but economic common terms and methods or techniques of similar work can help plan positive developments in the negotiations and the desired convergence of economic policies. Business Intelligence tools simplify the presentation of needed information for discussions and provide a foundation in starting up joint analysis of economic dynamics in the area to reach complete and actual lines of future possible

  7. Infrared thermography: possibilities and application to the study of material surfaces

    Directory of Open Access Journals (Sweden)

    Gayo, E.

    1992-09-01

    Full Text Available Non-destructive measurement techniques are revealing themselves as a very important tool in the different fields or research due to their very own nature. The Materials team of ICCET is developing, since some time ago, the application of one of these techniques —specifically speaking, infrarred thermography— to the follow-up and quantification of the moisture present in the buildings of the Architectural Heritage. At all events, that technique can be applied to any physical phenomenon involving a variation of temperature or emissivity. This paper shows different possible applications of infrared thermography.

    Las técnicas de medida no destructivas se están perfilando como un elemento muy importante en los distintos campos de investigación por su propio carácter. El equipo de Materiales del ICCET está desarrollando, desde hace algún tiempo, la aplicación de una de estas técnicas; concretamente la termografía infrarroja al seguimiento y cuantificación de humedades presentes en edificios del Patrimonio Arquitectónico. De cualquier manera, dicha técnica puede ser aplicable a cualquier fenómeno físico que conlleve una variación de temperatura o emisividad. En el presente trabajo se muestran distintas posibilidades de aplicación de la Termografía Infrarroja.

  8. New information and communication technologies in agriculture - factors, drivers and application possibilities

    Directory of Open Access Journals (Sweden)

    Róbert Szilágyi

    2012-06-01

    Full Text Available The new ICT technologies are not only fast developed but, in addition, are giving birth to newer systems and tools. The Internet network have become essential communication tools in business processes recently. Using the Internet by means of mobile appliances increases the possibilities. The agriculture has some speciality in information technology. The ICT adoption in the agriculture and main drivers has been examined. For the successful application the key lessons have to understand. To get a draft overview of Hungarian position there is part about it. In this part there are data about household communication devices the individuals ICT usage by age. The region differences in information technologies can be seen also. The final part of the paper there are some technology and application examples. The new devices like tablets and new services like Cloud Computing have great potential in agriculture. Cloud Computing provides better resource management and effective cost control. However, the business assessment of these technologies must not be done only on the basis of the technology and taken out of its environment randomly since the whole area is very complex.

  9. Genetic use restriction technologies and possible applications in the integrated pest management

    Directory of Open Access Journals (Sweden)

    Giliardi Dalazen

    Full Text Available ABSTRACT: Genetic use restriction technologies (GURTs were developed to preserve the intellectual property of genetically modified crops (GM and ensure the return of investments made by industry to obtain technology delivered through seeds. The aims of this review are to discuss the GURTs and analyze their possible applications in integrated management of agricultural pests. There are two classes of GURTs: T-GURTs (trait-based GURTs, wherein the generated seed are viable, but the next generation does not express the trait of agronomic interest, and V-GURT (variety-based GURTs, in which plants produce non viable seeds. However, beyond the seed protection purpose, the GURTs could have also other application to solve agronomic problems. One of the most important is the use of GURTs as a tool to restrict gene flow of GM traits to relative weeds. In addition, it is proposed the use of this technology in integrated weed management by preventing the GMs seed germination, which produces volunteer plants that compete with the crop of interest. Also, these volunteer plants may serve as alternative hosts for insects and pathogens in between crop seasons. The GURTs could contribute to the control of undesirable agents in agricultural systems, reducing the use of pesticides and increasing crop yields.

  10. Hydrothermal Detoxization of Slate Containing Asbestos and the Possibility of Application for Fertilizer of its Products

    Science.gov (United States)

    Myojin, Sachi; Kuroki, Toshihiro; Manabe, Wataru; Yamasaki, Chizuko; Yamasaki, Nakamichi

    2010-11-01

    Hydrothermal decomposition of slate (building materials) containing asbestos has been attempted by using a NH4H2PO4 solution. Firstly, the alteration of chrysotile as a starting material was investigated under hydrothermal conditions of 200° C, 12 hrs of reaction time and with a phosphate solution. It was confirmed that the original fibrous form of chrysotile had been perfectly collapsed by the SEM observation. The chrysotile (asbestos) disappeared to form Mg-Ca-Silicate (Ca7Mg2P6O24) estimated by XRD. The composition and chemical form of reaction products (Mg-Ca-Silicate) was predicted to application as a fertilizer. Fertilizer effect of these resulted product on cultivations of Japanese radish (leaves), soybeans and tomatoes, was examined by using a special medium of mixed soil with a low content of N, P, K and a thermal-treated zeolite one. The fertilizer effects of the product were compared to commercial fertilizers such as N, N-K-P and P types. In order to estimate the fertilizer effect, the size of crops, number of fruits and number of leaves were measured everyday. As a result, these hydrothermal products of slate containing asbestos were as good as commercial fertilizers on the market. Fruits groups especially had a good crop using the hydrothermal slate product. These results show that the main components of hydrothermal treatments slate are calcium silicate and magnesium phosphate. Its decomposition reaction products may have the possibility of application for fertilization of crops which require nucleic acid—phosphorus.

  11. The applications possibilities of the gamma-ray compton backscattering technique

    Energy Technology Data Exchange (ETDEWEB)

    Flechas, David; Gonzalez, Natalia; Sarmiento, Luis G.; Fajardo, Eduardo; Garzon, Claudia; Munoz, Juansebastian; Cristancho, Fernando [Universidad Nacional de Colombia, Bogota (Colombia). Dept. de Fisica

    2012-07-01

    Full text: X-rays have been for already longer than a century the instrument of choice when producing images of opaque objects. One important characteristic of the use of X-rays as an imaging tool is the geometrical arrangement in which the object under study is placed between the photons source and the imaging material (film or electronic device). This set-up cannot be realized in a multitude of situations of industrial interest. In those cases the source and the imaging device are limited to be at the same side of the object rendering impossible the use of present day's possibilities of X-ray imaging. It is in these cases where the technique discussed exhibits most of its power and advantages. By using the back-to-back emitted gamma-rays of the positron-decay of {sup 22}Na, the Gamma-Ray Compton Backscattering (GRCB) technique is able of building images of an object placed in front of the gamma-rays source. The set-up includes two detectors connected in time coincidence, one of them, a pixelated position- detector in charge of building the image and the other just providing the gating condition. The talk explains the working principle, shows some first images of hidden objects in soil, and discusses some of the prospective areas of application like oil industry and explosive landmines localization. (author)

  12. An analysis of the possibility of Macro Fiber Composite transducers application in modernized freight wagon

    Science.gov (United States)

    Płaczek, M.; Wróbel, A.; Buchacz, A.

    2016-08-01

    Paper presents an analysis of the possibility of application of piezoelectric foils - Macro Fiber Composite (MFC) in modernized freight wagons. It was verified if they can be successfully applied as sensors in developed system for structural health monitoring and in energy harvesting system. It is a part of a research project that aim is to develop a technology of freight wagons modernization. The goal of the project is to elongate the period between periodic repairs (by better corrosion protection) and improve conditions of exploitation of modernized wagons (easier unloading during winter conditions - no freezes of the charge to the freight wagon body shell). The additional aim is to develop system for structural health monitoring of the modernized body of the freight wagon as well as the system supporting management of a fleet of wagons using GPS system with power supply based on the energy recovered by MFC's from the wagon's vibrations during its exploitation. Results of laboratory tests as well as results of measurements on the real freight wagon during observed driving of the wagon are presented. At the same time measurements of the electric voltage generated by the MFC transducers excited by low frequencies harmonic excitation were verified.

  13. Factoring and Forfeiting in Slovakia and Possibilities of its Application in Wood-Working Industry

    Directory of Open Access Journals (Sweden)

    Mariana Sedliačiková

    2014-04-01

    Full Text Available Factoring is the contract negotiated continuous purchase of short-term debts, incurred by supplier due to the provision of unsecured credit supply. Factoring is a method of financing that can offer a lot to businesses, especially with its added value. This method mainly includes protection before customers’ insolvency, management of receivables, as well as the opportunity to dispose with the funds before the end of the maturity of receivables. Forfeiting is the purchase of export receivables on credit at the time of delivery. It is related to receivables with the future maturity denominated in freely convertible currency, and secured with a bank aval bill, letter of credit with deferred payment or a bank guarantee. The conditions, under which each company provides forfeiting, depend essentially on the creditworthiness of the applicant and customer, as well as creditworthiness of the bank that issued the payment instrument. The aim of the present paper is to analyze the factoring and forfeiting market in Slovakia and based on the analysis of this issue to propose and verify theoretical and practical possibilities of factoring and forfeiting financing in the selected wood-working company with the estimation of costs associated with their use.

  14. Estimation of effective temperatures in quantum annealers for sampling applications: A case study with possible applications in deep learning

    Science.gov (United States)

    Benedetti, Marcello; Realpe-Gómez, John; Biswas, Rupak; Perdomo-Ortiz, Alejandro

    2016-08-01

    An increase in the efficiency of sampling from Boltzmann distributions would have a significant impact on deep learning and other machine-learning applications. Recently, quantum annealers have been proposed as a potential candidate to speed up this task, but several limitations still bar these state-of-the-art technologies from being used effectively. One of the main limitations is that, while the device may indeed sample from a Boltzmann-like distribution, quantum dynamical arguments suggest it will do so with an instance-dependent effective temperature, different from its physical temperature. Unless this unknown temperature can be unveiled, it might not be possible to effectively use a quantum annealer for Boltzmann sampling. In this work, we propose a strategy to overcome this challenge with a simple effective-temperature estimation algorithm. We provide a systematic study assessing the impact of the effective temperatures in the learning of a special class of a restricted Boltzmann machine embedded on quantum hardware, which can serve as a building block for deep-learning architectures. We also provide a comparison to k -step contrastive divergence (CD-k ) with k up to 100. Although assuming a suitable fixed effective temperature also allows us to outperform one-step contrastive divergence (CD-1), only when using an instance-dependent effective temperature do we find a performance close to that of CD-100 for the case studied here.

  15. [Possibilities and limits of application of fluoride-containing varnish in caries prevention, for example, "Fluor-Protector" (2)].

    Science.gov (United States)

    Della Volpe, M

    1990-09-01

    Using selected literature, the author provides an overview of the possibilities and limits of fluoride varnish application in caries prophylaxis based on the example of Fluor-Protector. He concludes, as did de Bruyn and Arends (1987), that Fluor-Protector is a safe and effective agent that can prevent caries very effectively and is also promising for use as a desensitising substance.

  16. POSSIBILITY FOR APPLICATION OF LIQUEFIED GASES FOR PURIFICATION OF BARBERRY ALKALOIDS

    Directory of Open Access Journals (Sweden)

    Demyanenko D.V.

    2016-06-01

    Full Text Available Introduction. Biologically active substances (BAS of barberry roots represented by alkaloids of isoquinoline group are perspective substances for development of preparations with multiple pharmacological activities. However, now manufacture of them in Ukraine is stopped. One of the reasons of this is out-of-date production technologies of alkaloids involving use of toxic and/or flammable solvents. In the article possibility for application of liquefied gases in technology of obtaining of alkaloids from barberry roots has been studied. Materials and methods. Initial raw herb drug were barberry (Berberis vulgaris roots harvested in spring on the territory of Southern Ukraine. Their moisture content was 11%, comminuting degree was 0,5-1,4 mm. At the first stage purification of raw herb drug from lipophilic impurities (defatting was made with use of some liquefied gases: tetrafluoroethane, isobutane, difluorochloromethane and difluoromethane. Extraction of the alkaloid sum was made with difluoromethane mixed with various quantities of liquid ammonia or diethylamine as alkaline agent. Crude extracts were exposed to two-level liquefied-gas purification. At first the alkaloid bases were transformed into saline forms with aqueous solutions of acids and purified from ballast impurities with liquefied freon-22. Then alkaloid salts were reextracted from aqueous phase in the base form with liquefied mixture of difluoromethane and ammonia. Mixing of liquid phases was provided by creation of alternate gradients of temperatures and, as consequence, pressures between separators feeding alternately cool water into jacket of one of them, and warm water – into jacket of another one. Quantity of lipophilic ballast impurities and also weight of extractives were determined gravimetrically. Quantitative analysis of the alkaloid sum was made by titrimetric method after sedimentation of alkaloids with volumetric solution of phosphomolybdic acid. Results and discussion

  17. Application of Knowledge in Advergaming as a Possible Source of Competitive Advantage

    Directory of Open Access Journals (Sweden)

    Mráček Pavel

    2011-09-01

    Full Text Available The article focuses on the question of the utilization of knowledge in advergaming (an original tool of the marketing communication as a possible source of competitive advantage. Related terms are briefly described and the research was conducted within a group of young people in the Czech Republic. The research confirms that, just advergaming might have the potential for acquiring “consumers of the advertising message” and, consequently, the possible broadening of the knowledge of the company. The output then becomes the scheme for displaying the links and the utilization of the knowledge in the advergame itself.

  18. Environmental Risk Limits for several phosphate esters, with possible application as flame retardant

    NARCIS (Netherlands)

    Verbruggen EMJ; Rila JP; Traas TP; Posthuma-Doodeman CJAM; Posthumus R; SEC

    2006-01-01

    Maximum Permissible Concentrations (MPC), Negligible Concentrations (NC) and Serious Risk Concentrations (SRCeco) are derived for a number of phosphate esters that are possibly used as flame retardant. These environmental risk limits were derived for the compartments water, soil, and sediment on bas

  19. Study on the possibilities of dedicated CAD applications development for the furniture industry

    Directory of Open Access Journals (Sweden)

    Ioan Mocian

    2009-12-01

    Full Text Available This paper presents the results of a research for finding the best solutions to design and develop the CAD applications for the furniture industry. The solutions considered exclude the use of complementary software such as AutoCAD, Inventor or SolidWorks, the main target being stand-alone, cheap and easy to use solutions. The paper presents concepts of components typing in the furniture industry and thepossibilities to construct complex combinations of furniture using these typed components. A dedicated application for designing certain types of bookshelves is also presented. The application is stand-alone and it was written in the object oriented programming language VB.NET. The study has been carried out with partners from the furniture industry, whose opinions and views on this matter were of great help.

  20. Langevin equation with stochastic damping - Possible application to critical binary fluid

    Science.gov (United States)

    Jasnow, D.; Gerjuoy, E.

    1975-01-01

    We solve the familiar Langevin equation with stochastic damping to represent the motion of a Brownian particle in a fluctuating medium. A connection between the damping and the random driving forces is proposed which preserves quite generally the Einstein relation between the diffusion and mobility coefficients. We present an application to the case of a Brownian particle in a critical binary mixture.

  1. Possible application of the Environmental Relative Moldiness Index in France: A pilot study in Brittany

    Science.gov (United States)

    Our goal was to determine if the US Environmental Relative Moldiness Index (ERMI) scale might have application in France. Twenty homes in Brittany, north western region of France were classified by inspection as “Moldy” or “Non-Moldy”. Dust and air samples were collected (MiTest ...

  2. An analysis of possible applications of fuzzy set theory to the actuarial credibility theory

    Science.gov (United States)

    Ostaszewski, Krzysztof; Karwowski, Waldemar

    1992-01-01

    In this work, we review the basic concepts of actuarial credibility theory from the point of view of introducing applications of the fuzzy set-theoretic method. We show how the concept of actuarial credibility can be modeled through the fuzzy set membership functions and how fuzzy set methods, especially fuzzy pattern recognition, can provide an alternative tool for estimating credibility.

  3. Gold(I) N-heterocyclic carbene complexes with an "activable" ester moiety : Possible biological applications

    NARCIS (Netherlands)

    Bertrand, Benoit; Bodio, Ewen; Richard, Philippe; Picquet, Michel; Le Gendre, Pierre; Casini, Angela

    2015-01-01

    While N-heterocyclic carbenes (NHC) are ubiquitous ligands in catalysts for organic or industrial synthesis, their potential to form transition metal complexes for medicinal applications has still to be exploited. Within this frame, new Au(I)-NHC compounds have been synthesized and structurally char

  4. A summary of meteorological requirements for water vapor data and possible space shuttle applications

    Science.gov (United States)

    1976-01-01

    The accuracy of water vapor measurement required by modelers and forecasters at a number of scales of motion is discussed. Direct and indirect methods for operational use in obtaining atmospheric water vapor data are reviewed along with meteorological applications of water vapor data obtained by a space shuttle laboratory lidar system.

  5. The non-antibacterial effects and possible clinical applications of macrolide antibiotics

    Institute of Scientific and Technical Information of China (English)

    TONG Shi-liang; WANG Yuan-liang; GAO Wen-juan

    2006-01-01

    As one group of the most widely used oral antibacterial drugs, macrolides have been clinically applied for more than 50 years because of their safety and efficacy. Recently, the non-antibacterial applications of macrolides are frequently reported, such as the therapy of malignant tumor, exudative pleurisy, pulmonary fibrosis, rheumatoid arthritis, bronchiectasis, asthma, gastrointestinal peristalsis disorders, and so on with new pharmacological effects, including reverse of tumor resistance, anti-chemical adherence, anti-fibrosis, and modulations of gastrointestinal motility as well as immune activity. The in-depth research of marcolides' non-antibiotic actions can not only extend the application fields of macrolides, but provide a new way to treat some refractory diseases.

  6. ZnO - Wide Bandgap Semiconductor and Possibilities of Its Application in Optical Waveguide Structures

    OpenAIRE

    Struk Przemysław; Pustelny Tadeusz; Gołaszewska Krystyna; A. Borysiewicz Michał; Kamińska Eliana; Wojciechowski Tomasz; Piotrowska Anna

    2014-01-01

    The paper presents the results of investigations concerning the application of zinc oxide - a wideband gap semiconductor in optical planar waveguide structures. ZnO is a promising semiconducting material thanks to its attractive optical properties. The investigations were focused on the determination of the technology of depositions and the annealing of ZnO layers concerning their optical properties. Special attention was paid to the determination of characteristics of the refractive index of...

  7. Possibility Study of Scale Invariant Feature Transform (SIFT) Algorithm Application to Spine Magnetic Resonance Imaging.

    Science.gov (United States)

    Lee, Dong-Hoon; Lee, Do-Wan; Han, Bong-Soo

    2016-01-01

    The purpose of this study is an application of scale invariant feature transform (SIFT) algorithm to stitch the cervical-thoracic-lumbar (C-T-L) spine magnetic resonance (MR) images to provide a view of the entire spine in a single image. All MR images were acquired with fast spin echo (FSE) pulse sequence using two MR scanners (1.5 T and 3.0 T). The stitching procedures for each part of spine MR image were performed and implemented on a graphic user interface (GUI) configuration. Moreover, the stitching process is performed in two categories; manual point-to-point (mPTP) selection that performed by user specified corresponding matching points, and automated point-to-point (aPTP) selection that performed by SIFT algorithm. The stitched images using SIFT algorithm showed fine registered results and quantitatively acquired values also indicated little errors compared with commercially mounted stitching algorithm in MRI systems. Our study presented a preliminary validation of the SIFT algorithm application to MRI spine images, and the results indicated that the proposed approach can be performed well for the improvement of diagnosis. We believe that our approach can be helpful for the clinical application and extension of other medical imaging modalities for image stitching.

  8. Influence of functionalized nanoparticles on conformational stability of type I collagen for possible biomedical applications.

    Science.gov (United States)

    Kandamchira, Aswathy; Selvam, Sangeetha; Marimuthu, Nidhin; Janardhanan, Sreeram Kalarical; Fathima, Nishter Nishad

    2013-12-01

    Collagen-nanoparticle interactions are vital for many biomedical applications including drug delivery and tissue engineering applications. Iron oxide nanoparticles synthesized using starch template according to our earlier reported procedures were functionalized by treating them with Gum Arabic (GA), a biocompatible polysaccharide, so as to enhance the interaction between nanoparticle surfaces and collagen. Viscosity, circular dichroism (CD) and Fourier transform infrared spectroscopy (FTIR) techniques have been used to study the collagen-nanoparticle interactions. The relative viscosity for collagen-nanoparticle conjugate was found to increase with increase in concentration of the nanoparticle within the concentration range investigated, which is due to the aggregation of protein onto the surface of nanoparticle. The CD spectra for the collagen-nanoparticle at different concentration ratios do not have much variation in the Rpn values (ratio of positive peak intensity over negative peak intensity) after functionalization with GA. The variation of molar ellipticity values for collagen-nanoparticle is due to the glycoprotein present in GA. The collagen triple helical structure is maintained after interaction with nanoparticles. The FTIR spectra of native collagen, Coll-Fs (nanoparticle without functionalization) and Coll-FsG (nanoparticle functionalized with GA) show clearly the amide I, II, III bands, with respect to collagen. The ability of polysaccharide stabilized/functionalized nanoparticles to maintain the collagen properties would help in its biomedical applications.

  9. Visualization of CDA laboratory reports and long term trends as a possible EHR application for patients and physicians.

    Science.gov (United States)

    Obenaus, Manuel; Burgsteiner, Harald

    2014-01-01

    To increase the patient's acceptance of electronic health records and understanding for their laboratory findings a web application was developed which presents all parameters and possible deviations of standard values in a clear way and visualizes the time based trend of all recorded parameters graphically. Documents corresponding to the Clinical document architecture (CDA) R2 laboratory reports standard and a rapid prototyping framework called Groovy on Grails were used. This work shows, that it is possible to create a useful, standards based tool for patients and physicians with comparatively few resources - an application that could be in similar form a part of an electronic Health Record (EHR) system like the Austrian electronic Health Record (ELGA).

  10. THE REMOTE AND MOBILE AIR TRAFFIC CONTROL TOWER AND ITS POSSIBLE APPLICATION TO THE OPERATIONAL AREA

    Directory of Open Access Journals (Sweden)

    Tímea VAS

    2014-10-01

    Full Text Available The concept of remote and mobile Air Traffic Control Tower (ATC TWR and its development has started in Europe, Australia and also in the USA, in order to improve the efficiency of Air Traffic Management (ATM systems in terms of air transportation safety. These new technologies are applicable in many countries in peace time, but on mobility reasons these are promoted to achieve commitments in the operational area. This article describes the devices and range of equipment of mobile and remote tower, and their specifications, which can even serve a medium sized airport, furthermore examines, whether how can those provide the air traffic services at an operational airfield.

  11. Characterization and Possible Applications of Some Novel Cellulose Derivatives and Composites

    Institute of Scientific and Technical Information of China (English)

    P. Zugenmaier

    2005-01-01

    @@ 1Introduction Cellulose is a naturally occurring linear chain of 1-4 linked β-D-glucopyranose and exhibits great chemical variability and potentials in applications. The cell walls of all plants contain fibers of cellulose. It has long been harvested as commercial fibers from cotton, flax, hemp, sisal, jute and ramie or as wood, which is a common building material or used as a source for purified cellulose. Wood represents a composite material with cellulose as major part combined in excellent form with lignin and hemicelluloses creating a unique high strength and durable material and recently came again into focus as renewable energy resource.

  12. Studies on the potentiometric thallium(III)-selective carbon paste electrode and its possible applications

    Energy Technology Data Exchange (ETDEWEB)

    Vytras, K.; Khaled, E.; Jezkova, J. [Dept. of Analytical Chemistry, University of Pardubice (Czech Republic); Hassan, H.N.A. [Microanalytical Lab., National Research Centre, Dokki, Cairo (Egypt); Barsoum, B.N. [Dept. of Chemistry, Faculty of Science, Cairo University, Giza (Egypt)

    2000-05-01

    Construction, performance characteristics and applications of a carbon paste thallium(III) ion-selective electrode are described. The electrode, which is based on ion-associate compounds formed between cetylpyridinium and chlorothallate(III) complexes dissolved in tricresyl phosphate as pasting liquid, showed near-Nernstian response over the concentration range of 5.8 x 10{sup -6}-2.9 x 10{sup -3}mol/L. Potentiometric titrations of thallium(III) with cetylpyridinium chloride were affected by higher concentrations of excess halides, probably due to the formation of higher halogenothallates. (orig.)

  13. Integrated application of health improving methods of Pilates and Bodyflex for improving psychophysiological possibilities of students

    Directory of Open Access Journals (Sweden)

    Kozina Zh.L.

    2014-02-01

    Full Text Available Purpose: to determine the effect of complex application procedures Bodyflex and Pilates using information and communication technology on the level of psycho-physiological capabilities of students. Material: the study involved 46 university students. Research methods - physiological (speed detection of simple and complex reactions in different modes of testing, the level of functional mobility and strength of the nervous system, pedagogical experiment, methods of mathematical statistics. Results: the positive effect on the level of the developed technique psychophysiological capacities of students. The application of the developed technique in the experimental group showed a significant decrease in the latency time of a simple visual-motor reaction time latent complex visual-motor reaction time test run "level of functional mobility of nervous processes" in feedback mode. Found that the use of Bodyflex and Pilates promotes strength of nervous processes. Conclusions: the recommended use in the learning process of students of complex techniques of Pilates Bodyflex using information and communication technologies, increased levels of psychophysiological features, mobility and strength of the nervous processes.

  14. Possible molecular targets for therapeutic applications of caffeic acid phenethyl ester in inflammation and cancer

    Directory of Open Access Journals (Sweden)

    Ghulam Murtaza

    2015-03-01

    Full Text Available Of the various derivatives of caffeic acid, caffeic acid phenethyl ester (CAPE is a hydrophobic, bioactive polyphenolic ester obtained from propolis extract. The objective in writing this review article was to summarize all published studies on therapeutics of CAPE in inflammation and cancer to extract direction for future research. The possible molecular targets for the action of CAPE, include various transcription factors such as nuclear factor-κB, tissue necrosis factor-α, interleukin-6, cyclooxygenase-2, Nrf2, inducible nitric oxide synthase, nuclear factor of activated T cells, hypoxia-inducible factor-1α, and signal transducers and activators of transcription. Based on the valuable data on its therapeutics in inflammation and cancer, clinical studies of CAPE should also be conducted to explore its toxicities, if any.

  15. Influence of naturally occurring antioxidants on magnetic nanoparticles: risks, benefits, and possible therapeutic applications.

    Science.gov (United States)

    Durdík, Stefan; Vrbovská, Hanka; Olas, Adam; Babincová, Melánia

    2013-06-01

    We have studied interaction of well known antioxidant L-ascorbic acid with magnetic nanoparticles containing insoluble Fe(III) in their core. In analogy with ferritin, mobilization of iron in the form of water soluble Fe(II) was observed, especially pronounced at higher temperatures. In the presence of hydrogen peroxide cytotoxic hydroxyl radicals are produced. These results suggest possible harmful effects of widely used magnetic nanoparticles as a MRI contrast agents in combination with overload of organism with ascorbic acid in some specific conditions, like fever of patient. On the other hand combination of magnetic nanoparticles and ascorbic acid may be used for a cancer therapy using alternating magnetic field for the release of Fe(II) via Néel relaxation of magnetic moment of used nanoparticles. We have further found that lipoic acid is an efficient antioxidant scavenging hydroxyl radicals produced by Fenton reaction from Fe(II).

  16. Chemical modification of cobalt ferrite nanoparticles with possible application as asphaltene flocculant agent

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, G.E.; Clarindo, J.E.S.; Santo, K.S.E., E-mail: geiza.oliveira@ufes.br [Universidade Federal do Espirito Santo (CCE/DQUI/UFES), Vitoria, ES (Brazil). Centro de Ciencias Exatas. Dept. de Quimica; Souza Junior, F.G. [Universidade Federal do Rio de Janeiro (IMA/UFRJ), Rio de Janeiro, RJ (Brazil). Instituto de Macromoleculas

    2013-11-01

    Asphaltenes can cause enormous losses in the oil industry, because they are soluble only in aromatic solvents. Therefore, they must be removed from the petroleum before it is refined, using flocculant agents. Aiming to find new materials that can work as flocculant agents to asphaltenes, cobalt ferrite nanoparticles were chemically modified through acid-base reactions using dodecylbenzene sulfonic acid (DBSA) to increase their lipophilicity. Nanoparticle synthesis was performed using the co-precipitation method followed by annealing of these nanoparticles, aiming to change the structural phase. Modified and unmodified nanoparticles were tested by FTIR-ATR, XRD and TGA/DTA. In addition, precipitation onset of the asphaltenes was performed using modified and unmodified nanoparticles. These tests showed that modified nanoparticles have a potential application as flocculant agents used to remove asphaltenes before oil refining, since the presence of nanoparticles promotes the asphaltene precipitation onset with the addition of a small amount of non-solvent (author)

  17. Chemical modification of cobalt ferrite nanoparticles with possible application as asphaltene flocculant agent

    Directory of Open Access Journals (Sweden)

    G. E. Oliveira

    2013-06-01

    Full Text Available Asphaltenes can cause enormous losses in the oil industry, because they are soluble only in aromatic solvents. Therefore, they must be removed from the petroleum before it is refined, using flocculant agents. Aiming to find new materials that can work as flocculant agents to asphaltenes, cobalt ferrite nanoparticles were chemically modified through acid-base reactions using dodecylbenzene sulfonic acid (DBSA to increase their lipophilicity. Nanoparticle synthesis was performed using the co-precipitation method followed by annealing of these nanoparticles, aiming to change the structural phase. Modified and unmodified nanoparticles were tested by FTIR-ATR, XRD and TGA/DTA. In addition, precipitation onset of the asphaltenes was performed using modified and unmodified nanoparticles. These tests showed that modified nanoparticles have a potential application as flocculant agents used to remove asphaltenes before oil refining, since the presence of nanoparticles promotes the asphaltene precipitation onset with the addition of a small amount of non-solvent.

  18. Tissue engineering technology and its possible applications in oral and maxillofacial surgery.

    Science.gov (United States)

    Payne, Karl F B; Balasundaram, Indran; Deb, Sanjukta; Di Silvio, Lucy; Fan, Kathleen F M

    2014-01-01

    Tissue engineering is a rapidly advancing discipline that combines the attributes of biochemical and biomaterial engineering with cell transplantation to create bio-artificial tissues and organs. For the oral and maxillofacial surgeon, the reconstruction of maxillofacial defects in hard and soft tissues is an ongoing challenge. While autologous grafts and vascularised free flaps are the current gold standard, they are not without complications at both the donor and reconstructed sites. Tissue engineering, which aims to create tissue-matched, prefabricated, prevascularised bony or soft tissue composite grafts, or both, therefore has the potential to revolutionise practice in maxillofacial surgery. We review the technology of tissue engineering and its current and future applications within the specialty, and discuss contemporary obstacles yet to be overcome.

  19. [POSSIBILITIES OF VACUUM THERAPY APPLICATION IN DISORDERS OF VENOUS OUTFLOW IN ISLET GRAFTS].

    Science.gov (United States)

    Badyul, P O; Samoylenko, G E; Nor, N M; Slesarenko, K S

    2015-07-01

    The experience of "distressed" (problematic) flaps application in 33 patients with soft tissue defects over 2010-2014 years were analysed. It was proposed to use the local negative pressure for the prevention and treatment of complications associated with venous insufficiency or trombosis in using of plastics with vascularised complexes of tissues. Vacuum-therapy was conducted with the help of negative pressure apparatus "AGATE-Dnepr" (Ukraine) by attaching silver-containing polyurethane sponge on the operating zone, covering the flap with the surrounding skin netting band "Grassolind". The recommended standard of negative pressure of 75-125 mm Hg, both in impulse and in continuous mode was used. The high efficiency of vacuum-therapy for survival of grafts has been demonstrated. Thus, it might be considered as an effective element of prevention and treatment of complications associated with venous insufficiency or trombosis using of vascularised tissue complex plastics of defects.

  20. The scalable coherent interface, IEEE P1596, status and possible applications to data acquisition and physics

    Energy Technology Data Exchange (ETDEWEB)

    Gustavson, D.B.

    1990-01-01

    IEEE P1596, the Scalable Coherent Interface (formerly known as SuperBus) is based on experience gained while developing Fastbus (ANSI/IEEE 960-1986, IEC 935), Futurebus (IEEE P896.x) and other modern 32-bit buses. SCI goals include a minimum bandwidth of 1 GByte/sec per processor in multiprocessor systems with thousands of processors; efficient support of a coherent distributed-cache image of distributed shared memory; support for repeaters which interface to existing or future buses; and support for inexpensive small rings as well as for general switched interconnections like Banyan, Omega, or crossbar networks. This paper presents a summary of current directions, reports the status of the work in progress, and suggests some applications in data acquisition and physics. 7 refs.

  1. Magnetocaloric cycle with six stages: Possible application of graphene at low temperature

    Energy Technology Data Exchange (ETDEWEB)

    Reis, M. S., E-mail: marior@if.uff.br [Instituto de Física, Universidade Federal Fluminense, Av. Gal. Milton Tavares de Souza s/n, 24210-346 Niterói, RJ (Brazil)

    2015-09-07

    The present work proposes a thermodynamic hexacycle based on the magnetocaloric oscillations of graphene, which has either a positive or negative adiabatic temperature change depending on the final value of the magnetic field change. For instance, for graphenes at 25 K, an applied field of 2.06 T/1.87 T promotes a temperature change of ca. −25 K/+3 K. The hexacycle is based on the Brayton cycle and instead of the usual four steps, it has six stages, taking advantage of the extra cooling provided by the inverse adiabatic temperature change. This proposal opens doors for magnetic cooling applications at low temperatures.

  2. Molecular epidemiology, and possible real-world applications in breast cancer.

    Science.gov (United States)

    Ito, Hidemi; Matsuo, Keitaro

    2016-01-01

    Gene-environment interaction, a key idea in molecular epidemiology, has enabled the development of personalized medicine. This concept includes personalized prevention. While genome-wide association studies have identified a number of genetic susceptibility loci in breast cancer risk, however, the application of this knowledge to practical prevention is still underway. Here, we briefly review the history of molecular epidemiology and its progress in breast cancer epidemiology. We then introduce our experience with the trial combination of GWAS-identified loci and well-established lifestyle and reproductive risk factors in the risk prediction of breast cancer. Finally, we report our exploration of the cumulative risk of breast cancer based on this risk prediction model as a potential tool for individual risk communication, including genetic risk factors and gene-environment interaction with obesity.

  3. The Low Temperature CFB Gasifier - Further Test Results and Possible Applications

    DEFF Research Database (Denmark)

    Stoholm, P.; Nielsen, Rasmus Glar; Sarbæk, L.

    2002-01-01

    /agglomeration and corrosion when using difficult fuels such as agricultural biomass and many waste materials. This is achieved by pyrolysing the fuel at around 650°C in a circulating fluidised bed (CFB) chamber and subsequently gasifying the char down to only around 730°C in a slowly fluidised bubbling bed (BFB) chamber...... has mainly been Danish wheat straw containing 1,8 % potassium and 0,8 % chlorine (dry basis) and the bed material has been ordinary silica sand with no additives.The test results have showed a high retention of potassium (73-98%) and chlorine (23-75%) in the ash. At the same time the char loss...... was approx. 3,5 mass% of supplied amount of fuel, and the content of PAH in the ash was only around 2 mg/kg. The most recent test results and anticipated applications are described in this paper. Keywords: gasification, biomass conversion, circulating fluidised bed (CFB)...

  4. Development of a stacked detector system for the x-ray range and its possible applications

    Science.gov (United States)

    Maier, Daniel; Limousin, Olivier; Meuris, Aline; Pürckhauer, Sabina; Santangelo, Andrea; Schanz, Thomas; Tenzer, Christoph

    2014-07-01

    We have constructed a stacked detector system operating in the X-ray range from 0.5 keV to 250 keV that consists of a Si-based 64×64 DePFET-Matrix in front of a CdTe hybrid detector called Caliste-64. The setup is operated under laboratory conditions that approximate the expected environment of a space-borne observatory. The DePFET detector is an active pixel matrix that provides high count-rate capabilities with a near Fanolimited spectral resolution at energies up to 15 keV. The Caliste-64 hard X-ray camera consists of a 1mm thick CdTe crystal combined with very compact integrated readout electronics, constituting a high performance spectro-imager with event-triggered time-tagging capability in the energy range between 2 keV and 200 keV. In this combined geometry the DePFET detector works as the Low Energy Detector (LED) while the Caliste-64 - as the High Energy Detector (HED) - detects predominantly the high energetic photons that have passed the LED. In addition to the individual optimization of both detectors, we use the setup to test and optimize the performance of the combined detector system. Side-effects like X-ray fluorescence photons, electrical crosstalk, and mutual heating have negative impacts on the data quality and will be investigated. Besides the primary application as a combined imaging detector system with high sensitivity across a broad energy range, additional applications become feasible. Via the analysis of coincident events in both detectors we can estimate the capabilities of the setup to be used as a Compton camera and as an X-ray polarimeter - both desirable functionalities for use in the lab as well as for future X-ray missions.

  5. Possible applications of melatonin in the treatment of patients with surgical diseases

    Directory of Open Access Journals (Sweden)

    V. M. Sedov

    2015-01-01

    Full Text Available Since the widespread introduction of minimally invasive laparoscopic techniques in abdominal surgery there was a question - what are their physiological differences from operations withapproach by laparotomy. The study of these differences, mechanisms and their correction allows you to bring the results of operations with open approach to the laparoscopic. However, the possibility of an effective systemic exposure, allowing adapting body reaction to surgical procedures remains unresolved. To date, the use of melatonin in surgical practice is based on its functions as a neurotransmitter that can potentiate some natural protective reaction of the body. The paper analyzes the effects of melatonin, you can use as a biological adaptogenic control which generally acts as a trigger to launch a diver-seprocesses, including reparative ones in the body. The use of adaptive mechanisms initiated by melatonin in response to surgical trauma and tumor processes can be successfully applied to improve the results of surgical treatment of patients with surgical diseases operated as open and laparoscopic access.

  6. Exploring the possibilities of cryogenic cooling in liquid chromatography for biological applications: a proof of principle.

    Science.gov (United States)

    Eghbali, Hamed; Sandra, Koen; Tienpont, Bart; Eeltink, Sebastiaan; Sandra, Pat; Desmet, Gert

    2012-02-21

    The possibilities to use cryogenic cooling to trap components in liquid chromatography was investigated. In a first step, van 't Hoff plots were measured with a reversed-phase column using the temperature control unit of a conventional high performance liquid chromatography (HPLC) system to gain insight in the retention behavior of proteins at low temperatures. It was estimated that retention factors in the range of k = 10(4) could be achieved at T = -20 °C for lysozyme, indicating that temperature is a usable parameter to trap components in LC. In a next step, trapping experiments were carried out on a nano-LC system, equipped with a UV-detector, using a commercial reversed-phase column. An in-house built setup, allowing cooling of a segment of the column down to temperatures below T = -20 °C, was used to trap components. Experiments were conducted under isocratic and gradient conditions with methanol as organic solvent. It is demonstrated that, by thermally trapping and elution of components, an enhanced S/N ratio and decreased peak widths can be obtained. At the same time, a significant increase in pressure drop occurs during the cooling process. Limitations and benefits of the technique are further discussed.

  7. Virtual positron emission tomography/computed tomography-bronchoscopy: possibilities, advantages and limitations of clinical application

    Energy Technology Data Exchange (ETDEWEB)

    Seemann, Marcus D. [University of Magdeburg, Department of Radiology and Nuclear Medicine, Magdeburg (Germany); Schaefer, Juergen F. [Eberhard-Karls University, Department of Diagnostic Radiology, Tuebingen (Germany); Englmeier, Karl-Hans [Institute of Medical Informatics, GSF-National Research Center for Environment and Health, Neuherberg (Germany)

    2007-03-15

    The aim of this study was to demonstrate the possibilities, advantages and limitations of virtual bronchoscopy using data sets from positron emission tomography (PET) and computed tomography (CT). Twelve consecutive patients with lung cancer underwent PET/CT. PET was performed with F-18-labelled 2-[fluorine-18]-fluoro-2-deoxy-D-glucose ({sup 18}F-FDG). The tracheobronchial system was segmented with a volume-growing algorithm, using the CT data sets, and visualized with a shaded-surface rendering method. The primary tumours and the lymph node metastases were segmented for virtual CT-bronchoscopy using the CT data set and for virtual PET/CT-bronchoscopy using the PET/CT data set. Virtual CT-bronchoscopy using the low-dose or diagnostic CT facilitates the detection of anatomical/morphological structure changes of the tracheobronchial system. Virtual PET/CT-bronchoscopy was superior to virtual CT-bronchoscopy in the detection of lymph node metastases (P=0.001), because it uses the CT information and the molecular/metabolic information from PET. Virtual PET/CT-bronchoscopy with a transparent colour-coded shaded-surface rendering model is expected to improve the diagnostic accuracy of identification and characterization of malignancies, assessment of tumour staging, differentiation of viable tumour tissue from atelectases and scars, verification of infections, evaluation of therapeutic response and detection of an early stage of recurrence that is not detectable or is misjudged in comparison with virtual CT-bronchoscopy. (orig.)

  8. Carbon nanotube-based electrochemical biosensing platforms: fundamentals, applications, and future possibilities.

    Science.gov (United States)

    Luong, John H T; Male, Keith B; Hrapovic, Sabahudin

    2007-01-01

    Biosensors can be considered as a most plausible and exciting application area for nanobiotechnology. The recent bloom of nanofabrication technology and biofunctionalization methods of carbon nanotubes (CNTs) has stimulated significant research interest to develop CNT-based biosensors for monitoring biorecognition events and biocatalytic processes. The unique properties of CNTs, rolled-up sheets of carbon atoms with a diameter less than 1 nm, offer excellent prospects for interfacing biological recognition events with electronic signal transduction. CNT-based biosensors could be developed to sense only a few or even a single molecule of a chemical or biological agent. Both hydrogen peroxide and NADH, two by-products of over 300 oxidoreductases, are efficiently oxidized by CNT-modified electrodes at significantly lower potentials with minimal surface fouling. This appealing feature enables the development of useful biosensors for diversified applications. Aligned CNT "forests" can act as molecular wires to allow efficient electron transfer between the detecting electrode and the redox centers of enzymes to fabricate reagentless biosensors. Electrochemical sensing for DNA can greatly benefit from the use of CNT based platforms since guanine, one of the four bases, can be detected with significantly enhanced sensitivity. CNTs fluoresce, or emit light after absorbing light, in the near infrared region and retain their ability to fluoresce over time. This feature will allow CNT-based sensors to transmit information from inside the body. The combination of micro/nanofabrication and chemical functionalization, particularly nanoelectrode assembly interfaced with biomolecules, is expected to pave the way to fabricate improved biosensors for proteins, chemicals, and pathogens. However, several technical challenges need to be overcome to tightly integrate CNT-based platforms with sampling, fluidic handling, separation, and other detection principles. The biosensing platform

  9. Exploration mission enhancements possible with power beaming. [Space Applications Power Beaming

    Energy Technology Data Exchange (ETDEWEB)

    Bamberger, J.A.; Coomes, E.P. (Pacific Northwest Lab., Richland, WA (USA)); Segna, D.R. (USDOE Richland Operations Office, WA (USA))

    1990-10-01

    A key factor in the exploration and development of the space frontier is the availability of energy where and when it is needed. Currently all space satellites and platforms include self-contained power systems that supply the energy necessary to accomplish mission objectives. An alternative approach is to couple advanced high power system with energy beam transmitters and energy receivers to form an infrastructure of a space power utility where a central power system provides power to multiple users. Major space activities, such as low Earth orbit space commercialization and the colonization of the Moon or Mars, would benefit significantly from a central power generation and transmission system. This paper describes the power-beaming concept and system components as applied to space power generation and distribution in support of the Space Exploration Initiative. Beam-power scenarios are discussed including commonality of systems and hardware with cargo transport vehicles, power beaming from orbit to stationary and mobile users on the Lunar and Mars surfaces, and other surface applications. 6 refs.

  10. Optical and electrical properties of NiO for possible dielectric applications

    Directory of Open Access Journals (Sweden)

    Johannes R. Botha

    2011-01-01

    Full Text Available Nickel oxide (NiO is a versatile wide band gap semiconductor material. At present, transparent conducting oxide films find application as transparent electrodes and window coatings for opto-electronic devices but most are n-type. However p-type conducting films, of which NiO is one, are required as optical windows for devices where minority carrier injection is required. In this study, nickel (Ni was resistively deposited on glass substrates and oxidised (isochronally in oxygen at temperatures ranging from 300 ˚C to 600 ˚C. The oxidised Ni layers were subsequently characterised using scanning electron microscopy (SEM, X-ray diffraction (XRD and UV-visible photospectrometry in the range 200 nm – 1000 nm. The four point probe method (van der Pauw geometry was used to determine the sheet resistances of the oxidised films. SEM results of the surface revealed a strong dependence of the surface texture and particle size on the oxidation temperature and time. XRD performed on the oxidised Ni indicated progressive transformation from nanograined polycrystalline Ni to NiO at elevated temperatures. Film thicknesses, particle sizes, energy band gap and wavelength-dependent refractive indices were determined from transmission and absorbance data.

  11. Ion acceleration from intense laser-generated plasma: methods, diagnostics and possible applications

    Directory of Open Access Journals (Sweden)

    Torrisi Lorenzo

    2015-06-01

    Full Text Available Many parameters of non-equilibrium plasma generated by high intensity and fast lasers depend on the pulse intensity and the laser wavelength. In conditions favourable for the target normal sheath acceleration (TNSA regime the ion acceleration from the rear side of the target can be enhanced by increasing the thin foil absorbance through the use of nanoparticles and nanostructures promoting the surface plasmon resonance effect. In conditions favourable for the backward plasma acceleration (BPA regime, when thick targets are used, a special role is played by the laser focal position with respect to the target surface, a proper choice of which may result in induced self-focusing effects and non-linear acceleration enhancement. SiC detectors employed in the time-of-flight (TOF configuration and a Thomson parabola spectrometer permit on-line diagnostics of the ion streams emitted at high kinetic energies. The target composition and geometry, apart from the laser parameters and to the irradiation conditions, allow further control of the plasma characteristics and can be varied by using advanced targets to reach the maximum ion acceleration. Measurements using advanced targets with enhanced the laser absorption effect in thin films are presented. Applications of accelerated ions in the field of ion source, hadrontherapy and nuclear physics are discussed.

  12. Non-thermal atmospheric-pressure plasma possible application in wound healing.

    Science.gov (United States)

    Haertel, Beate; von Woedtke, Thomas; Weltmann, Klaus-Dieter; Lindequist, Ulrike

    2014-11-01

    Non-thermal atmospheric-pressure plasma, also named cold plasma, is defined as a partly ionized gas. Therefore, it cannot be equated with plasma from blood; it is not biological in nature. Non-thermal atmospheric-pressure plasma is a new innovative approach in medicine not only for the treatment of wounds, but with a wide-range of other applications, as e.g. topical treatment of other skin diseases with microbial involvement or treatment of cancer diseases. This review emphasizes plasma effects on wound healing. Non-thermal atmospheric-pressure plasma can support wound healing by its antiseptic effects, by stimulation of proliferation and migration of wound relating skin cells, by activation or inhibition of integrin receptors on the cell surface or by its pro-angiogenic effect. We summarize the effects of plasma on eukaryotic cells, especially on keratinocytes in terms of viability, proliferation, DNA, adhesion molecules and angiogenesis together with the role of reactive oxygen species and other components of plasma. The outcome of first clinical trials regarding wound healing is pointed out.

  13. Novel fluorescent CdTe quantum dot-thymine conjugate—synthesis, properties and possible application

    Science.gov (United States)

    Rodzik, Łucja; Lewandowska-Łańcucka, Joanna; Szuwarzyński, Michał; Szczubiałka, Krzysztof; Nowakowska, Maria

    2017-01-01

    Novel, highly fluorescent cadmium telluride quantum dots conjugated with thymine and stabilized with thioglycolic acid were obtained and characterized. Successful formation of the conjugate was confirmed by elemental analysis, and UV-vis, fluorescence and Fourier transform infrared spectroscopies. Crystal structure and composition of the conjugates were characterized with xray diffraction and x-ray photoelectron spectroscopy. The size of the conjugates was 4-6 nm as demonstrated using atomic force microscopy and high resolution transmission electron microscopy imaging. The plasmon resonance fluorescence band at 540 nm on excitation at 351 nm was observed for these nanoparticles. The intensity of this band increased with the increase in the amount of conjugated thymine with no shift in its position. Based on the fluorescence measurements it was found that the CdTe-thymine conjugate interacted efficiently and selectively not only with adenine, a nucleobase complementary to thymine, but also with adenine-containing modified nucleosides, i.e., 5‧-deoxy-5‧-(methylthio)adenosine and 2‧-O-methyladenosine, the urinary tumor markers which allow monitoring of the disease progression. To the best of our knowledge, as yet, there have been no studies presented in literature on that type of the interaction with CdTe-thymine conjugates. Therefore, the system presented can be considered as a working component of a selective adenine/adenosine biosensor with potential application in cancer diagnosis.

  14. Nitroxides as antioxidants – possibilities of their application in chemoprevention and radioprotection

    Directory of Open Access Journals (Sweden)

    Sabina Tabaczar

    2011-01-01

    Full Text Available Nitroxides as stabile organic radicals were used initially as spin labels in spectroscopy of electron paramagnetic resonance (EPR with respect to parameters such as pH of an intercellular environment, oxygenation of cells and tissues, fluidity of biological membranes, conformational state and topography of proteins. Nitroxides have also been used in biology and medicine as contrast agents in magnetic resonance imaging (MRI. When their antioxidant activities were discovered, an era of research on the potential utility of these agents began. Nitroxides can modulate the redox state of the cell by participation in oxidation/reduction reactions. Therefore, they are extensively examined in various models of oxidative stress. The antioxidant effect of nitroxides is a result of their ability to catalyze dismutation of superoxide radical (superoxide dismutase-like activity, inhibit lipid peroxidation, prevent Fenton and Haber-Weiss reactions by oxidation of transition metal ions to a higher oxidative state, and confer catalase-like activity on heme proteins. In the present paper the antioxidative mechanisms of nitroxides are presented. The relation between structure, function and the rate of nitroxide reduction inside cells and tissues is also presented. The application of nitroxides in chemoprevention and radioprotection is discussed.

  15. The Cyclic Antibacterial Peptide Enterocin AS-48: Isolation, Mode of Action, and Possible Food Applications

    Directory of Open Access Journals (Sweden)

    María José Grande Burgos

    2014-12-01

    Full Text Available Enterocin AS-48 is a circular bacteriocin produced by Enterococcus. It contains a 70 amino acid-residue chain circularized by a head-to-tail peptide bond. The conformation of enterocin AS-48 is arranged into five alpha-helices with a compact globular structure. Enterocin AS-48 has a wide inhibitory spectrum on Gram-positive bacteria. Sensitivity of Gram-negative bacteria increases in combination with outer-membrane permeabilizing treatments. Eukaryotic cells are bacteriocin-resistant. This cationic peptide inserts into bacterial membranes and causes membrane permeabilization, leading ultimately to cell death. Microarray analysis revealed sets of up-regulated and down-regulated genes in Bacillus cereus cells treated with sublethal bacteriocin concentration. Enterocin AS-48 can be purified in two steps or prepared as lyophilized powder from cultures in whey-based substrates. The potential applications of enterocin AS-48 as a food biopreservative have been corroborated against foodborne pathogens and/or toxigenic bacteria (Listeria monocytogenes, Bacillus cereus, Staphylococcus aureus, Escherichia coli, Salmonella enterica and spoilage bacteria (Alicyclobacillus acidoterrestris, Bacillus spp., Paenibacillus spp., Geobacillus stearothermophilus, Brochothrix thermosphacta, Staphylococcus carnosus, Lactobacillus sakei and other spoilage lactic acid bacteria. The efficacy of enterocin AS-48 in food systems increases greatly in combination with chemical preservatives, essential oils, phenolic compounds, and physico-chemical treatments such as sublethal heat, high-intensity pulsed-electric fields or high hydrostatic pressure.

  16. The Cyclic Antibacterial Peptide Enterocin AS-48: Isolation, Mode of Action, and Possible Food Applications

    Science.gov (United States)

    Grande Burgos, María José; Pérez Pulido, Rubén; López Aguayo, María del Carmen; Gálvez, Antonio; Lucas, Rosario

    2014-01-01

    Enterocin AS-48 is a circular bacteriocin produced by Enterococcus. It contains a 70 amino acid-residue chain circularized by a head-to-tail peptide bond. The conformation of enterocin AS-48 is arranged into five alpha-helices with a compact globular structure. Enterocin AS-48 has a wide inhibitory spectrum on Gram-positive bacteria. Sensitivity of Gram-negative bacteria increases in combination with outer-membrane permeabilizing treatments. Eukaryotic cells are bacteriocin-resistant. This cationic peptide inserts into bacterial membranes and causes membrane permeabilization, leading ultimately to cell death. Microarray analysis revealed sets of up-regulated and down-regulated genes in Bacillus cereus cells treated with sublethal bacteriocin concentration. Enterocin AS-48 can be purified in two steps or prepared as lyophilized powder from cultures in whey-based substrates. The potential applications of enterocin AS-48 as a food biopreservative have been corroborated against foodborne pathogens and/or toxigenic bacteria (Listeria monocytogenes, Bacillus cereus, Staphylococcus aureus, Escherichia coli, Salmonella enterica) and spoilage bacteria (Alicyclobacillus acidoterrestris, Bacillus spp., Paenibacillus spp., Geobacillus stearothermophilus, Brochothrix thermosphacta, Staphylococcus carnosus, Lactobacillus sakei and other spoilage lactic acid bacteria). The efficacy of enterocin AS-48 in food systems increases greatly in combination with chemical preservatives, essential oils, phenolic compounds, and physico-chemical treatments such as sublethal heat, high-intensity pulsed-electric fields or high hydrostatic pressure. PMID:25493478

  17. A bacteria-based bead for possible self-healing marine concrete applications

    Science.gov (United States)

    Palin, D.; Wiktor, V.; Jonkers, H. M.

    2016-08-01

    This work presents a bacteria-based bead for potential self-healing concrete applications in low-temperature marine environments. The bead consisting of calcium alginate encapsulated bacterial spores and mineral precursor compounds was assessed for: oxygen consumption, swelling, and its ability to form a biocomposite in a simulative marine concrete crack solution (SMCCS) at 8 °C. After six days immersion in the SMCCS the bacteria-based beads formed a calcite crust on their surface and calcite inclusions in their network, resulting in a calcite-alginate biocomposite. Beads swelled by 300% to a maximum diameter of 3 mm, while theoretical calculations estimate that 0.112 g of the beads were able to produce ˜1 mm3 of calcite after 14 days immersion; providing the bead with considerable crack healing potential. The bacteria-based bead shows great potential for the development of self-healing concrete in low-temperature marine environments, while the formation of a biocomposite healing material represents an exciting avenue for self-healing concrete research.

  18. Investigation of the possibilities of phosphogypsum application for building partitioning Walls - elements of a prefabricated house

    Directory of Open Access Journals (Sweden)

    Rajković Miloš B.

    2002-01-01

    Full Text Available Phosphogypsum is a waste product in the manufacture of phosphoric acid from phosphorite and sulphuric acid by so-called "wet process" and represents a refuse that is as such simply thrown away. Phosphogypsum which is produced by "dihydrating procedure" contains not only various impurties but also radionuclides, which limits its construction use. Performed testings point to the complexity of phosphogypsum structure and composition while the electron microscope's pictures showed its different crystal composition compared to the natural gypsum. The calcined and refined phosphogypsum can be used for partition walls manufacture. To avoid the danger of the possible presence of radionuclides it is better to use the mixture of natural gypsum and phosphogypsum for this purpose. Substantial saving of materials and economic effect can be achieved in this way. The analyse performed in this work have shown significant presence of radionuclides in phosphogypsum. Gammaspectrometric measurements of radioactivity have determined substantial radioactivity of phosphogypsum. Using the maximum tolerated level values that are legally accepted, as well as equations to calculate indexes of tolerated radionuclide presence, an index of 2.23 has been determined for interiors and 1.13 for exteriors, i.e. 0.64 in case of roads. On the basis of the maximum tolerated level of radioactive building materials contamination (< 1, forbiden is the use of phosphogypsum in interiors, allowed (≈ 1 in exteriors and roads. The tests of heavy metal components in phosphogypsum have proved their presence in the amounts potentially producing consequences if present in closed spaces. That is conditioned by the phosphogypsum quantity, as well as by the area of space partitioned.

  19. Topographic site effects: numerical studies and a possible application to the regional Newmark approach

    Science.gov (United States)

    Torgoev, Almaz; Havenith, Hans-Balder

    2015-04-01

    2D elasto-dynamic modelling of the seismic response was performed with the UDEC software (ver. 4.01, ITASCA). The numerical studies have been performed for six models constructed from real topographic settings of the landslide-prone slopes situated in the Mailuu-Suu River Valley, Southern Kyrgyzstan. The main focus of our studies was the development of proxies for a regional mapping of topographic site effects. The main parameter we studied was the Arias Intensity (Ia). This parameter is applied to the GIS-based Newmark method, which regionally maps the seismically-induced landslide susceptibility. This method performs a mapping of the Ia values via empirical attenuation laws, which mainly account for the regional geometric spreading. An input of site effects is generally not included in these laws. While total site effects normally integrate both geologic and topographic inputs, our paper focuses only on the pure topographic effects. The numerical studies showed that the amplification of the Arias Intensity depends on two main factors: the frequency content of the input signal and the site settings. The first parameter can be predicted for wide areas through attenuation laws. With respect to the impact of site settings on Ia amplification, our studies show that convex surface morphologies with a longer baseline induce amplification in the low frequency domain, while those with a shorter baseline amplify the seismic shaking in the higher frequency domain. The link between topographic site amplification and the size of a surface morphology is identified. Those developed proxies are adapted for application in conventional GIS software platforms.

  20. ZnO - Wide Bandgap Semiconductor and Possibilities of Its Application in Optical Waveguide Structures

    Directory of Open Access Journals (Sweden)

    Struk Przemysław

    2014-08-01

    Full Text Available The paper presents the results of investigations concerning the application of zinc oxide - a wideband gap semiconductor in optical planar waveguide structures. ZnO is a promising semiconducting material thanks to its attractive optical properties. The investigations were focused on the determination of the technology of depositions and the annealing of ZnO layers concerning their optical properties. Special attention was paid to the determination of characteristics of the refractive index of ZnO layers and their coefficients of spectral transmission within the UV-VIS-NIR range. Besides that, also the mode characteristics and the attenuation coefficients of light in the obtained waveguide structures have been investigated. In the case of planar waveguides, in which the ZnO layers have not been annealed after their deposition, the values of the attenuation coefficient of light modes amount to a~ 30 dB/cm. The ZnO layers deposited on the heated substrate and annealed by rapid thermal annealing in an N2 and O2 atmosphere, are characterized by much lower values of the attenuation coefficients: a~ 3 dB/cm (TE0 and TM0 modes. The ZnO optical waveguides obtained according to our technology are characterized by the lowest values of the attenuation coefficients a encountered in world literature concerning the problem of optical waveguides based on ZnO. Studies have shown that ZnO layers elaborated by us can be used in integrated optic systems, waveguides, optical modulators and light sources.

  1. Possible applications of instruments of measurement of the customer value in the operations of logistics companies

    Directory of Open Access Journals (Sweden)

    2011-12-01

    Full Text Available Background: The growing popularity in recent years of marketing concepts of putting clients in the centre of the interest of companies as well as easy access to data related to customers' behaviors led to the increase of the importance of such concepts as the profitability and the value of the customer. But the customer value in not an unequivocal concept. It can be defined and measured individually depending on the needs of a company, an industry character, objectives or a time horizon. Methods: The following, most often used, methods for measuring customer value were selected, described and analyzed from the point of view of their usefulness: different types of the portfolio method (e.g. two-steps and three-steps one, nine-field matrix, etc, multidimensional analysis of customers, analysis of the rentability of customers, model PCV, ABC method, RFM method and CLV indicator. Results: The advantages and disadvantages of each of analyzed methods were presented and evaluated. The possible use of each of the methods was presented and discussed. In the sector of logistics companies, the measurement of the customer value can be an effective tool in managing the customer relationships and in increasing their profitability. Since there is no only one universal way of measuring the customer value, which is appropriate for every selected industry branch, the choice of a particular method depends on many factors, such as a business profile or number of clients served by a company. Conclusions: The aim of the identification of key customers is to facilitate the optimal allocation of resources of the company. Not all customers are equally important for the company, and the company is not able and should not try to acquire and satisfy needs of each customer. It should be remembered, that the evaluation of the customer value in logistics companies should not be restricted to only one of discussed methods. The analysis presented in this paper indicates, that

  2. Handheld multi-channel LAPS device as a transducer platform for possible biological and chemical multi-sensor applications

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, Torsten [Aachen University of Applied Sciences, Juelich Campus, Institute of Nano- and Biotechnologies, Ginsterweg 1, 52428 Juelich (Germany); Institute of Bio- and Nanosystems (IBN-2), Research Centre Juelich GmbH, 52425 Juelich (Germany); Molina, Roberto [Aachen University of Applied Sciences, Juelich Campus, Institute of Nano- and Biotechnologies, Ginsterweg 1, 52428 Juelich (Germany); Yoshinobu, Tatsuo [Tohoku University, Department of Electronic Engineering, 6-6-05 Aramaki Aza Aoba, Aoba-ku, Sendai, Miyagi 980-8579 (Japan); Kloock, Joachim P. [Aachen University of Applied Sciences, Juelich Campus, Institute of Nano- and Biotechnologies, Ginsterweg 1, 52428 Juelich (Germany); Institute of Bio- and Nanosystems (IBN-2), Research Centre Juelich GmbH, 52425 Juelich (Germany); Biselli, Manfred; Canzoneri, Michelangelo; Schnitzler, Thomas [Aachen University of Applied Sciences, Juelich Campus, Institute of Nano- and Biotechnologies, Ginsterweg 1, 52428 Juelich (Germany); Schoening, Michael J. [Aachen University of Applied Sciences, Juelich Campus, Institute of Nano- and Biotechnologies, Ginsterweg 1, 52428 Juelich (Germany); Institute of Bio- and Nanosystems (IBN-2), Research Centre Juelich GmbH, 52425 Juelich (Germany)], E-mail: m.j.schoening@fz-juelich.de

    2007-12-01

    The light-addressable potentiometric sensor is a promising technology platform for multi-sensor applications and lab-on-chip devices. However, many prior LAPS developments suffer from their lack in terms of non-portability, insufficient robustness, complicate handling, etc. Hence, portable and robust LAPS-based measurement devices have been investigated by the authors recently. In this work, a 'chip card'-based light-addressable potentiometric sensor system is presented. The utilisation of ordinary 'chip cards' allows an easy handling of different sensor chips for a wide range of possible applications. The integration of the electronic and the mechanical set-up into a single reader unit results in a compact design with the benefits of portability and low required space. In addition, the presented work includes a new multi-frequency measurement procedure, based on an FFT algorithm, which enables the simultaneous real-time measurement of up to 16 sensor spots. The comparison between the former batch-LAPS and the new FFT-based LAPS set-up will be presented. The immobilisation of biological cells (CHO: Chinese hamster ovary) demonstrates the possibility to record their metabolic activity with 16 measurement spots on the same chip. Furthermore, a Cd{sup 2+}-selective chalcogenide-glass layer together with a pH-sensitive Ta{sub 2}O{sub 5} layer validates the use of the LAPS for chemical multi-sensor applications.

  3. Possible applications of the LEAP motion controller for more interactive simulated experiments in augmented or virtual reality

    Science.gov (United States)

    Wozniak, Peter; Vauderwange, Oliver; Mandal, Avikarsha; Javahiraly, Nicolas; Curticapean, Dan

    2016-09-01

    Practical exercises are a crucial part of many curricula. Even simple exercises can improve the understanding of the underlying subject. Most experimental setups require special hardware. To carry out e. g. a lens experiments the students need access to an optical bench, various lenses, light sources, apertures and a screen. In our previous publication we demonstrated the use of augmented reality visualization techniques in order to let the students prepare with a simulated experimental setup. Within the context of our intended blended learning concept we want to utilize augmented or virtual reality techniques for stationary laboratory exercises. Unlike applications running on mobile devices, stationary setups can be extended more easily with additional interfaces and thus allow for more complex interactions and simulations in virtual reality (VR) and augmented reality (AR). The most significant difference is the possibility to allow interactions beyond touching a screen. The LEAP Motion controller is a small inexpensive device that allows for the tracking of the user's hands and fingers in three dimensions. It is conceivable to allow the user to interact with the simulation's virtual elements by the user's very hand position, movement and gesture. In this paper we evaluate possible applications of the LEAP Motion controller for simulated experiments in augmented and virtual reality. We pay particular attention to the devices strengths and weaknesses and want to point out useful and less useful application scenarios.

  4. Analysis of Possible Application of High-Temperature Nuclear Reactors to Contemporary Large-Output Steam Power Plants on Ships

    Directory of Open Access Journals (Sweden)

    Kowalczyk T.

    2016-04-01

    Full Text Available This paper is aimed at analysis of possible application of helium to cooling high-temperature nuclear reactor to be used for generating steam in contemporary ship steam-turbine power plants of a large output with taking into account in particular variable operational parameters. In the first part of the paper types of contemporary ship power plants are presented. Features of today applied PWR reactors and proposed HTR reactors are discussed. Next, issues of load variability of the ship nuclear power plants, features of the proposed thermal cycles and results of their thermodynamic calculations in variable operational conditions, are presented.

  5. GLYCERINE: FROM A INCONVINIENT BIODIESEL BY-PRODUCT TO A POSSIBLE APPLICATION AS A FLOCCULANT IN WATER TREATMENT

    Directory of Open Access Journals (Sweden)

    GAUTO, Marcelo Antunes

    2010-01-01

    Full Text Available Glycerin is a by-product obtained during the biodiesel manufacture, through the transesterification reaction of vegetal oils. The prevision of excedent glycerine in the next few years, due to the increasing of the biodiesel production in Brazil, has been generating a discussion about new applications to this by-product. This article presents a theoretical study about the possible synthesis of a new flocculant agent, from semi-refined glycerine and p-nitrobenzoic acid to produce a quaternary ammonium salt, to be used in water treatment. The reactions which would occur during the synthesis of the flocculant agent and the necessary tests to the product validation are presented.

  6. Utilization possibilities of hydrocarbon fractions obtained by waste plastic pyrolysis: energetic utilization and applications in polymer composites

    Energy Technology Data Exchange (ETDEWEB)

    Miskolczi, Norbert; Borsodi, Nikolett; Angyal, Andras [University of Pannonia, MOL Department of Hydrocarbon and Coal Processing (Hungary)], email: mnorbert@almos.uni-pannon.hu, email: borsodinikolett@almos.uni-pannon.hu, email: angyala@almos.uni-pannon.hu

    2011-07-01

    With the energy crisis and the rising concerns about the environment, energy-saving measures are urgently needed. Each year about 300M tons of plastic wastes are produced world-wide and governments are now focusing on recycling and reusing these products to save significant amounts of energy. The aim of this paper was to analyze the products which can be obtained from waste plastic and determine their possible uses. Pyrolysis of commercial waste plastics was done in a reactor at 500-600 degree celsius and the products were then analyzed using several methods. Results showed that the pyrolysis produces gases, naphtha, middle distillates and heavy oils. The properties of these products were also determined and it was found that they have the potential to be used in fuel-like and additive producing applications. This study highlighted that pyrolysis of waste polymers can yield useful products.

  7. Neutral Metal 1,2-Dithiolenes: Preparations, Properties and Possible Applications of Unsymmetrical in Comparison to the Symmetrical

    Directory of Open Access Journals (Sweden)

    George A. Mousdis

    2012-06-01

    Full Text Available This paper is an overview concerning the preparations and properties as well as possible applications of neutral (one component metal 1,2-dithiolenes (and selenium analogues. The structural, chemical, electrochemical, optical and electrical behavior of these complexes depend strongly on the nature of ligand and/or the metal. The results of unsymmetrical in comparison to those of symmetrical complexes related to the properties of materials in the solid state are primarily discussed. The optical absorption spectra exhibit strong bands in the near IR spectral region ca. 700 to ca. 1950 nm. X-ray crystal structure solutions show that the complexes usually have square-planar geometry with S–S and/or M–S contacts. Some of them behave as semiconductors or conductors (metals and are stable in air. The cyclic voltammograms at negative potentials are different from the corresponding potentials of tetrathiafulvalenes (TTFs. As a consequence, the LUMO bands occur at much lower levels than those of TTFs. Consequently, electrical measurements under conditions of field effect transistors exhibit n-type or ambipolar behavior. Illumination of materials with high power lasers exhibits non-linear optical behavior. These properties enable metal 1,2-dithiolene complexes to be classified as promising candidates for optical and electronic applications, (e.g., saturable absorbers, ambipolar inverters.

  8. Radiation applications in art and archaeometry X-ray fluorescence applications to archaeometry. Possibility of obtaining non-destructive quantitative analyses

    Energy Technology Data Exchange (ETDEWEB)

    Milazzo, Mario E-mail: mario.milazzo@unimi.it

    2004-01-01

    The possibility of obtaining quantitative XRF analysis in archaeometric applications is considered in the following cases: - Examinations of metallic objects with irregular surface: coins, for instance. - Metallic objects with a natural or artificial patina on the surface. - Glass or ceramic samples for which the problems for quantitative analysis rise from the non-detectability of matrix low Z elements. The fundamental parameter method for quantitative XRF analysis is based on a numerical procedure involving he relative values of XRF lines intensity. As a consequence it can be applied also to the experimental XRF spectra obtained for metallic objects if the correction for the irregular shape consists only in introducing a constant factor which does not affect the XRF intensity relative value. This is in fact possible in non-very-restrictive conditions for the experimental set up. The finenesses of coins with a superficial patina can be evaluated by resorting to the measurements of Rayleigh to Compton scattering intensity ratio at an incident energy higher than the one of characteristic X-ray. For glasses and ceramics the measurements of the Compton scattered intensity of the exciting radiation and the use of a proper scaling law make possible to evaluate the matrix absorption coefficients for all characteristic X-ray line energies.

  9. A possible cosmological application of some thermodynamic properties of the black body radiation in $n-$dimensional Euclidean spaces

    CERN Document Server

    Gonzalez-Ayala, Julian; Cordero, Rubén; Angulo-Brown, F

    2015-01-01

    In this work we present the generalization of some thermodynamic properties of the black body radiation (BBR) towards an $n-$dimensional Euclidean space. For this case the Planck function and the Stefan-Boltzmann law have already been given by Landsberg and de Vos and some adjustments by Menon and Agrawal. However, since then no much more has been done on this subject and we believe there are some relevant aspects yet to explore. In addition to the results previously found we calculate the thermodynamic potentials, the efficiency of the Carnot engine, the law for adiabatic processes and the heat capacity at constant volume. There is a region at which an interesting behavior of the thermodynamic potentials arise, maxima and minima appear for the $n-d$ BBR system at very high temperatures and low dimensionality, suggesting a possible application to cosmology. Finally we propose that an optimality criterion in a thermodynamic framework could have to do with the $3-d$ nature of the universe.

  10. A Possible Cosmological Application of Some Thermodynamic Properties of the Black Body Radiation in n-Dimensional Euclidean Spaces

    Directory of Open Access Journals (Sweden)

    Julian Gonzalez-Ayala

    2015-06-01

    Full Text Available In this work, we present the generalization of some thermodynamic properties of the black body radiation (BBR towards an n-dimensional Euclidean space. For this case, the Planck function and the Stefan–Boltzmann law have already been given by Landsberg and de Vos and some adjustments by Menon and Agrawal. However, since then, not much more has been done on this subject, and we believe there are some relevant aspects yet to explore. In addition to the results previously found, we calculate the thermodynamic potentials, the efficiency of the Carnot engine, the law for adiabatic processes and the heat capacity at constant volume. There is a region at which an interesting behavior of the thermodynamic potentials arises: maxima and minima appear for the n—dimensional BBR system at very high temperatures and low dimensionality, suggesting a possible application to cosmology. Finally, we propose that an optimality criterion in a thermodynamic framework could be related to the 3—dimensional nature of the universe.

  11. Studies on the possibility of more effective use of water glass thanks to application of selected methods of hardening

    Directory of Open Access Journals (Sweden)

    M. Stachowicz

    2010-04-01

    Full Text Available In this work, we undertook an attempt at determination of the possibility of efficiency increase of application of hydrated sodium silicate hardened with selected methods. The results of the influence of dielectric drying method (in the process of innovative microwave heating as well as classical drying on tensile strength of molding sands have been presented. The effectiveness of both hardening methods has been evaluated through comparison of the obtained tensile strength values to the amount of water glass used for preparation of molding sand. Five kinds of hydrated sodium silicate have been used in these studies. It has been found that microwave heating process positively influences tensile strength of molding sands prepared with addition of all the available on the market binding agents (including those, most frequently used in foundry kinds of 145, 149 and 150. It has been demonstrated that the innovative microwave heating, while compared to convection drying process, guarantees better strength characteristics, significantly exceeding them, especially in case of very small contents of binding agent of 1.5% and 2.5%. Decrease of drying processes effectiveness, in case of convection method as well as dielectric one, has been observed with increase of binding agent content in molding sand to over 3.5%.

  12. Possible Applications of Hardening Slurries with Fly Ash from Thermal Treatment of Municipal Sewage Sludge in Environmental Protection Structures

    Science.gov (United States)

    Falacinski, Paweł; Szarek, Łukasz

    2016-06-01

    In Poland, in recent years, there has been a rapid accumulation of sewage sludge - a by-product in the treatment of urban wastewater. This has come about as a result of infrastructure renewal, specifically, the construction of modern sewage treatment plants. The more stringent regulations and strategic goals adopted for modern sewage management have necessitated the application of modern engineering methodology for the disposal of sewage sludge. One approach is incineration. As a consequence, the amount of fly ash resulting from the thermal treatment of municipal sewage sludge has grown significantly. Hence, intensive work is in progress for environmentally safe management of this type of waste. The aim of the experiment was to evaluate the possibility of using the fly ash that results from municipal sewage sludge thermal treatment (SSTT) as an additive to hardening slurries. This type of hardening slurry with various types of additives, e.g. coal combustion products, is used in the construction of cut-off walls in hydraulic structures. The article presents the technological and functional parameters of hardening slurries with an addition of fly ash obtained by SSTT. Moreover, the usefulness of these slurries is analysed on the basis of their basic properties, i.e. density, contractual viscosity, water separation, structural strength, volumetric density, hydraulic conductivity, compressive and tensile strength. The mandated requirements for slurries employed in the construction of cut-off walls in flood embankments are listed as a usefulness criteria. The article presents the potential uses of fly ash from SSTT in hardening slurry technology. It also suggests directions for further research to fully identify other potential uses of this by-product in this field.

  13. Possible application of scintillation detectors with semiconductor PMT for cosmic-neutron and gamma-ray detection

    Science.gov (United States)

    Mokrousov, M. I.; Vostrukhin, A. A.; Karpushkina, N. E.; Malakhov, A. V.

    2016-09-01

    Solar system planets exploration and cosmic neutrons and gamma-ray flux research have been dynamically evolving for several decades. Different scintillation crystals are used for this purpose along with photo signal receivers, such as vacuum photomultiplier tubes (PMT). Many studies are being performed in order to provide alternative devices for photon signal capture: PIN-diodes,avalanche photodiodes, semiconductor silicon photomultipliers. We study the applicability of a silicon PMT in employing highresolution crystals in space applications.

  14. Discovery of possible gene relationships through the application of self-organizing maps to DNA microarray databases.

    Directory of Open Access Journals (Sweden)

    Rocio Chavez-Alvarez

    Full Text Available DNA microarrays and cell cycle synchronization experiments have made possible the study of the mechanisms of cell cycle regulation of Saccharomyces cerevisiae by simultaneously monitoring the expression levels of thousands of genes at specific time points. On the other hand, pattern recognition techniques can contribute to the analysis of such massive measurements, providing a model of gene expression level evolution through the cell cycle process. In this paper, we propose the use of one of such techniques--an unsupervised artificial neural network called a Self-Organizing Map (SOM-which has been successfully applied to processes involving very noisy signals, classifying and organizing them, and assisting in the discovery of behavior patterns without requiring prior knowledge about the process under analysis. As a test bed for the use of SOMs in finding possible relationships among genes and their possible contribution in some biological processes, we selected 282 S. cerevisiae genes that have been shown through biological experiments to have an activity during the cell cycle. The expression level of these genes was analyzed in five of the most cited time series DNA microarray databases used in the study of the cell cycle of this organism. With the use of SOM, it was possible to find clusters of genes with similar behavior in the five databases along two cell cycles. This result suggested that some of these genes might be biologically related or might have a regulatory relationship, as was corroborated by comparing some of the clusters obtained with SOMs against a previously reported regulatory network that was generated using biological knowledge, such as protein-protein interactions, gene expression levels, metabolism dynamics, promoter binding, and modification, regulation and transport of proteins. The methodology described in this paper could be applied to the study of gene relationships of other biological processes in different organisms.

  15. POSSIBILITIES OF APPLICATION OF THE HACCP SYSTEM RULES IN THE PROCESS OF IMPROVING THE QUALITY OF EDUCATION IN AGRICULTURAL SECONDARY SCHOOLS

    Directory of Open Access Journals (Sweden)

    Maria Kaczmarek

    2014-09-01

    Full Text Available The paper presents theoretical issues concerning the possibilities of application of the HACCP system rules in the process of improving the quality of education in secondary schools. The carried out analysis show that it is possible to apply the HACCP system rules in secondary schools. Implementation of the HACCP system rules in schools can be beneficial in four areas: economically-financial, organisational, educational and social. Moreover, the education security would increase, the intellectual loss and failure of students would be diminished and on the educational market an increase of competitiveness and trust to school and its graduates would be observed.

  16. A Study of the dimensional accuracy obtained by low cost 3D printing for possible application in medicine

    Science.gov (United States)

    Kitsakis, K.; Alabey, P.; Kechagias, J.; Vaxevanidis, N.

    2016-11-01

    Low cost 3D printing' is a terminology that referred to the fused filament fabrication (FFF) technique, which constructs physical prototypes, by depositing material layer by layer using a thermal nozzle head. Nowadays, 3D printing is widely used in medical applications such as tissue engineering as well as supporting tool in diagnosis and treatment in Neurosurgery, Orthopedic and Dental-Cranio-Maxillo-Facial surgery. 3D CAD medical models are usually obtained by MRI or CT scans and then are sent to a 3D printer for physical model creation. The present paper is focused on a brief overview of benefits and limitations of 3D printing applications in the field of medicine as well as on a dimensional accuracy study of low-cost 3D printing technique.

  17. Are spontaneous fractures possible? An example of clinical application for personalised, multiscale neuro-musculo-skeletal modelling.

    Science.gov (United States)

    Viceconti, Marco; Taddei, Fulvia; Cristofolini, Luca; Martelli, Saulo; Falcinelli, Cristina; Schileo, Enrico

    2012-02-02

    Elderly frequently present variable degrees of osteopenia, sarcopenia, and neuromotor control degradation. Severely osteoporotic patients sometime fracture their femoral neck when falling. Is it possible that such fractures might occur without any fall, but rather spontaneously while the patient is performing normal movements such as level walking? The aim of this study was to verify if such spontaneous fractures are biomechanically possible, and in such case, which conditions of osteoporosis, sarcopenia, and neuromotor degradation could produce them. To the purpose, a probabilistic multiscale body-organ model validated against controlled experiments was used to predict the risk of spontaneous fractures in a population of 80-years old women, with normal weight and musculoskeletal anatomy, and variable degree of osteopenia, sarcopenia, and neuromotor control degradation. A multi-body inverse dynamics sub-model, coupled to a probabilistic neuromuscular sub-model, and to a femur finite element sub-model, formed the multiscale model, which was run within a Monte Carlo stochastic scheme, where the various parameters were varied randomly according to well defined distributions. The model predicted that neither extreme osteoporosis, nor extreme neuromotor degradation alone are sufficient to predict spontaneous fractures. However, when the two factors are combined an incidence of 0.4% of spontaneous fractures is predicted for the simulated population, which is consistent with clinical reports. When the model represented only severely osteoporotic patients, the incidence of spontaneous fractures increased to 29%. Thus, is biomechanically possible that spontaneous femoral neck fractures occur during level walking, due to a combination of severe osteoporosis and severe neuromotor degradation.

  18. Application of technical devices with the elements of sport for development of level of physical preparedness and psychophysiological possibilities of children 1-5 years

    Directory of Open Access Journals (Sweden)

    Lakhno E.G.

    2010-10-01

    Full Text Available The necessity of application of technical devices is grounded for development of level of physical preparedness and психофизиологических possibilities of children. Technical devices are developed with the elements of basket-ball, sporting tourism and by the analogues of the system of M.Montessori. In research 52 children of age-dependent group of 1-2 years, 56 children of 3-4 years, 56 children of 4-5 years took part. It is set that application of methods with the use of technical devices with the elements of sport is instrumental there are 1-5 years in the increase of indexes of physical preparedness and psychophysiological possibilities of children.

  19. Development of an eco-protocol for seaweed chlorophylls extraction and possible applications in dye sensitized solar cells

    Science.gov (United States)

    Armeli Minicante, S.; Ambrosi, E.; Back, M.; Barichello, J.; Cattaruzza, E.; Gonella, F.; Scantamburlo, E.; Trave, E.

    2016-07-01

    Seaweeds are a reserve of natural dyes (chlorophylls a, b and c), characterized by low cost and easy supply, without potential environmental load in terms of land subtraction, and also complying with the requirements of an efficient waste management policy. In particular, the brown seaweed Undaria pinnatifida is a species largely present in the Venice Lagoon area, and for it a removal strategy is actually mandatory. In this paper, we set-up an eco-protocol for the best extraction and preparation procedures of the pigment, with the aim of finding an easy and affordable method for chlorophyll c extraction, exploring at the same time the possibility of using these algae within local sustainable management integrated strategies, among which the possible use of chlorophylls as a dye source in dye sensitized solar cells (DSSCs) is investigated. Experimental results suggest that the developed protocols are useful to optimize the chlorophyll c extraction, as shown by optical absorption spectroscopy measurements. The DSSCs built with the chlorophyll extracted by the proposed eco-protocol exhibit solar energy conversion efficiencies are similar to those obtained following extraction protocols with larger environmental impacts.

  20. Preparation of Composited Graphene/PEDOT:PSS Film for Its Possible Application in Graphene-based Organic Solar Cells

    Institute of Scientific and Technical Information of China (English)

    YU Yue; LI Meicheng; CHU Lihua; YU Hakki; Wodtke A M; ZHAO Yan; ZHANG Zhongmo

    2015-01-01

    The interface between graphene and organic layers is a key factor responsible for the performance of gra-phene-based organic solar cells (OSCs). In this paper, we focus on coating PEDOT:PSS onto the surface of graphene. We demonstrate two approaches, applying UV/Ozone treatment on graphene and modifying PEDOT:PSS with Zonyl, to get a PEDOT:PSS well-coated graphene film . Our results prove that both methods can be effective to solve the interface issue between graphene and PEDOT: PSS. Thereby it shows a positive application of the composited gra-phene/PEDOT:PSS film on graphene-based OSCs.

  1. Preparation of Composited Graphene/PEDOT:PSS Film for Its Possible Application in Graphene-based Organic Solar Cells

    Institute of Scientific and Technical Information of China (English)

    YU; Yue; LI; Meicheng; CHU; Lihua; YU; Hakki; Wodtke; A.M.; ZHAO; Yan; ZHANG; Zhongmo

    2015-01-01

    The interface between graphene and organic layers is a key factor responsible for the performance of graphene-based organic solar cells(OSCs). In this paper, we focus on coating PEDOT:PSS onto the surface of graphene. We demonstrate two approaches, applying UV/Ozone treatment on graphene and modifying PEDOT:PSS with Zonyl, to get a PEDOT:PSS well-coated graphene film. Our results prove that both methods can be effective to solve the interface issue between graphene and PEDOT: PSS. Thereby it shows a positive application of the composited graphene/PEDOT:PSS film on graphene-based OSCs.

  2. Conceivability & Possibility

    DEFF Research Database (Denmark)

    2009-01-01

    Conceivability & Possibility – The Prospects of a Reductive Account of Modality er et speciale skrevet af Asger Steffensen, Århus Universitet, 2009. Specialet handler om tænkelighed og mulighed og om udsigterne for en reduktiv teori om modalitet. Med andre ord er specialet et forsøg på at vise, a...

  3. VibroCV: a computer vision-based vibroarthrography platform with possible application to Juvenile Idiopathic Arthritis.

    Science.gov (United States)

    Wiens, Andrew D; Prahalad, Sampath; Inan, Omer T

    2016-08-01

    Vibroarthrography, a method for interpreting the sounds emitted by a knee during movement, has been studied for several joint disorders since 1902. However, to our knowledge, the usefulness of this method for management of Juvenile Idiopathic Arthritis (JIA) has not been investigated. To study joint sounds as a possible new biomarker for pediatric cases of JIA we designed and built VibroCV, a platform to capture vibroarthrograms from four accelerometers; electromyograms (EMG) and inertial measurements from four wireless EMG modules; and joint angles from two Sony Eye cameras and six light-emitting diodes with commercially-available off-the-shelf parts and computer vision via OpenCV. This article explains the design of this turn-key platform in detail, and provides a sample recording captured from a pediatric subject.

  4. Theory of a continuous stripe melting transition in a two-dimensional metal: a possible application to cuprate superconductors.

    Science.gov (United States)

    Mross, David F; Senthil, T

    2012-06-29

    We construct a theory of continuous stripe melting quantum phase transitions in two-dimensional metals and the associated Fermi surface reconstruction. Such phase transitions are strongly coupled but yet theoretically tractable in situations where the stripe ordering is destroyed by proliferating doubled dislocations of the charge stripe order. The resulting non-Landau quantum critical point has strong stripe fluctuations which we show decouple dynamically from the Fermi surface even though static stripe ordering reconstructs the Fermi surface. We discuss connections to various stripe phenomena in the cuprates. We point out several puzzling aspects of old experimental results [G. Aeppli et al., Science 278, 1432 (1997)] on singular stripe fluctuations in the cuprates, and provide a possible explanation within our theory. These results may thus have been the first observation of non-Landau quantum criticality in an experiment.

  5. Central Nervous System-Peripheral Immune System Dialogue in Neurological Disorders: Possible Application of Neuroimmunology in Urology.

    Science.gov (United States)

    Park, Hyun-Sun; Park, Min-Jung; Kwon, Min-Soo

    2016-05-01

    Previous concepts of immune-privileged sites obscured the role of peripheral immune cells in neurological disorders and excluded the consideration of the potential benefits of immunotherapy. Recently, however, numerous studies have demonstrated that the blood-brain barrier in the central nervous system is an educational barrier rather than an absolute barrier to peripheral immune cells. Emerging knowledge of immune-privileged sites suggests that peripheral immune cells can infiltrate these sites via educative gates and that crosstalk can occur between infiltrating immune cells and the central nervous system parenchyma. This concept can be expanded to the testis, which has long been considered an immune-privileged site, and to neurogenic bladder dysfunction. Thus, we propose that the relationship between peripheral immune cells, the brain, and the urologic system should be considered as an additional possible mechanism in urologic diseases, and that immunotherapy might be an alternative therapeutic strategy in treating neurogenic bladder dysfunction.

  6. Studies of Reduced Graphene Oxide and Graphite Oxide in the Aspect of Their Possible Application in Gas Sensors.

    Science.gov (United States)

    Drewniak, Sabina; Muzyka, Roksana; Stolarczyk, Agnieszka; Pustelny, Tadeusz; Kotyczka-Morańska, Michalina; Setkiewicz, Maciej

    2016-01-15

    The paper presents the results of investigations on resistance structures based on graphite oxide (GRO) and graphene oxide (rGO). The subject matter of the investigations was thaw the sensitivity of the tested structures was affected by hydrogen, nitrogen dioxide and carbon dioxide. The experiments were performed at a temperature range from 30 °C to 150 °C in two carrier gases: nitrogen and synthetic air. The measurements were also aimed at characterization of the graphite oxide and graphene oxide. In our measurements we used (among others) techniques such as: Atomic Force Microscopy (AFM); Scanning Electron Microscopy (SEM); Raman Spectroscopy (RS); Fourier Transform Infrared Spectroscopy (FT-IR) and X-ray Photoelectron Microscopy (XPS). The data resulting from the characterizations of graphite oxide and graphene oxide have made it possible to interpret the obtained results from the point of view of physicochemical changes occurring in these structures.

  7. Discovery of underground argon with low level of radioactive 39Ar and possible applications to WIMP dark matter detectors

    CERN Document Server

    Galbiati, C

    2007-01-01

    We report on the first measurement of 39Ar in argon from underground natural gas reservoirs. The gas stored in the US National Helium Reserve was found to contain a low level of 39Ar. The ratio of 39Ar to stable argon was found to be <=4x10-17 (84% C.L.), less than 5% the value in atmospheric argon (39Ar/Ar=8x10-16). The total quantity of argon currently stored in the National Helium Reserve is estimated at 1000 tons. 39Ar represents one of the most important backgrounds in argon detectors for WIMP dark matter searches. The findings reported demonstrate the possibility of constructing large multi-ton argon detectors with low radioactivity suitable for WIMP dark matter searches.

  8. The possibilities of atmospheric plasma-spraying application to obtain hydroxyapatite coatings on the stainless steel samples

    Directory of Open Access Journals (Sweden)

    Mihailović Marija D.

    2013-01-01

    Full Text Available For decades, the standard metallic materials for hip implants, besides the 316LVM stainless steel, were titanium- and cobalt/chromium-based alloys. Although bioinert, due to their corrosion resistance, they are not biocompatible. Contemporary surgical implants are not made just of bioinert metal anymore, but with deposited bioactive hydroxyapatite (HAp coating. Hydroxyapatite is chemically identical with the mineral constituent of bones and teeth, what besides its biocompatibility provides bioactivity as well. The HAp limitations are, however, weak tensile strength and low fatigue resistance for long term loadings, if used alone. This is the reason for HAp to be deposited onto the surgical implant, and to enable its bioactivity, what means intergrowth with bones, and therefore the long-lasting and mechanical stable non-cemented prosthesis. This is important predominantly because the need for such prostheses for younger population, and a better life quality. There are several contemporary techniques that have been used for deposition of these coatings onto the metal implant. The possibilities of atmospheric plasma-spraying for obtaining the stable HAp coatings on the 316LVM stainless steel, ordinary used as a standard material for hip implants production are presented in this paper. The coatings of a commercially available hydroxyapatite powder were plasma-sprayed onto the specimens of medical grade 316LVM stainless steel under various operating conditions. The optical microscopy was used for microstructure and porosity characterization, while coating morphology and Ca/P ratio were analyzed using SEM equipped with EDX. Coating microstructure varied from a porous to a glassy structure, depending on operating conditions applied and coating thickness. Coating porosity was determined to be at the lower required limit requested for the bone-coating intergrowth possibility, but nevertheless adhesion measurements showed good results. The Ca/P ratio was

  9. The possibilities of the application of some species of sage (Salvia L. as auxiliaries in the treatment of some diseases

    Directory of Open Access Journals (Sweden)

    NATASA D. MITIC

    2003-06-01

    Full Text Available The chemical composition of four essential oils of four species of sage (Salvia officinalis L., Salvia pratensis L., Salvia glutinosa L. and Salvia aethiopis L. are examined by GC-FID and GC-MS analysis. The presence of some components in the essential oil (mono- and sesquiterpene determines the pharmacological effects and therapeutical application of a plant species. Salvia officinalis L. gives the highest yield of oil (1.1 %, while the lowest is in Salvia pratensis L. (0.1 %. The investigations included the determination of the antimicrobic activities of the essential oils by the diffusion method and the oil of Salvia pratensis L. proved to have the highest activity.

  10. Development and Application of a Moveability Index to Quantify Possibilities for Physical Activity in the Built Environment of Children

    DEFF Research Database (Denmark)

    Buck, Christoph; Pohlabeln, Hermann; Huybrechts, Inge;

    2011-01-01

    Several studies show that urban forms are environmental correlates of physical activity. Most of these studies used data based on questionnaires while only a few used geographic information systems (GIS) to objectively assess urban forms. Based on GIS data, we applied a kernel density method to m...... survey of the IDEFICS study. Regression analyses revealed a modest but significant impact of the built environment on the physical activity of 596 school children in the study region, supporting the potential application of the moveability index.......Several studies show that urban forms are environmental correlates of physical activity. Most of these studies used data based on questionnaires while only a few used geographic information systems (GIS) to objectively assess urban forms. Based on GIS data, we applied a kernel density method...

  11. The application of the International Classification of Functioning, Disability, and Health in psychiatry: possible reasons for the lack of implementation.

    Science.gov (United States)

    Álvarezz, Ana Sabela

    2012-02-01

    The purpose of this article was to examine the application of the International Classification of Functioning, Disability, and Health (ICF) in the field of psychiatry in the last 10 yrs since the ICF was launched. The hypothesis is that the application of the ICF in the field of psychiatry has not been yet much explored. Therefore, the objective of this article was to provide reasons to explain the difficult implementation of the ICF in this field, which in turn, might account for the lack of studies. A literature search was conducted using the terms ICF AND mental illness OR mental disorders OR psychiatry in titles, abstracts, and key words of articles collected in the databases ISI Web of Knowledge, ScienceDirect and Medline from 2001 to 2010. A total of 64 full-length articles were retrieved and reviewed, and among them, 13 were eventually included in this review because they were related to the ICF in psychiatry. Of the 13 studies identified concerning the ICF and mental disorders, 7 focus on the implementation of the ICF in the clinical practice, and 6 are theoretical papers discussing the potential benefits of the ICF for the field of psychiatry. A number of reasons can be suggested to explain the paucity of studies on the use of the ICF in psychiatry in the last 10 yrs: (1) the novelty of the ICF and the dominance of the medical model, (2) the belief that disability is just about physical conditions, (3) the influence of medication on capacity and performance, (4) the complex structure of the ICF, (5) the intrinsic limitations of the ICF, and (6) limitations in the accessibility of the ICF to some medical professionals.

  12. Possible Greenland

    DEFF Research Database (Denmark)

    2012-01-01

    Organizing in Greenland is a complex matter. We have been on an arctic odyssey exploring the different aspects of the Greenlandic reality and have created a publication in which a wide range of Greenlandic and international profiles and stakeholders give their opinion and visions for the future...... development in Greenland. By creating a platform for a wide range of ideas about the Possible Greenland to be discussed now and in the future, we give Greenlanders and Greenlandic decision makers access to the greatest amount of possible solutions to the challenges they are facing. We look more closely...... at Greenland's structure, and ask some threshold questions. Which aspects of society are rooted in our human hardware? And, if we had the rare opportunity to build a new nation, what would we choose for ourselves? We hope this will inspire an open, imaginative and thoroughly human discussion about how...

  13. Thermal hygienization of excess anaerobic sludge: a possible self-sustained application of biogas produced in UASB reactors.

    Science.gov (United States)

    Borges, E S M; Godinho, V M; Chernicharo, C A L

    2005-01-01

    The main current trends in final disposal of sludge from Wastewater Treatment Plants (WTP) include: safe use of nutrients and organic matter in agriculture, sludge disinfection and restricted use in landfill. As to sludge hygienization, helminth eggs have been used as a major parameter to determine the effectiveness of such process, and its inactivation can be reached by means of thermal treatment, under varying temperature and other conditions. In such context, the objective of this research was to determine how effectively biogas produced in UASB reactors could be used as a source of calorific energy for the thermal hygienization of excess anaerobic sludge, with Ascaris lumbricoides eggs being used as indicator microorganisms, and whether the system can operate on a self-sustained basis. The experiments were conducted in a pilot-scale plant comprising one UASB reactor, two biogas holders and one thermal reactor. The investigation proved to be of extreme importance to developing countries, since it leads to a simplified and fully self-sustainable solution for sludge hygienization, while making it possible to reuse such material for agricultural purposes. It should be also noted that using biogas from UASB reactors is more than sufficient to accomplish the thermal hygienization of all excess sludge produced by this system, when used for treating domestic sewage.

  14. Dynamically forced cantilever system: A piezo-polymer characterization tool with possible application for micromechanical HF resonator devices

    Science.gov (United States)

    Schwödiauer, Reinhard

    2005-04-01

    A cantilever system, driven to a dynamically forced oscillation by a small piezoelectric specimen is presented as a simple and accurate tool to determine the converse dynamic piezocoefficient up to several kHz. The piezoelectric sample is mounted on top of a reflective cantilever where it is free to oscillate without any mechanical constraint. A Nomarsky-interferometer detects the induced cantilever displacement. The presented technique is especially suited for a precise characterization of small and soft piezoelectric polymer-samples with rough surfaces. The capability of the dynamically forced cantilever principle is demonstrated with a LiNbO3 crystal and with a porous ferroelectretic polypropylene foam. Results from measurements between 400 Hz and 5 kHz were found to be in excellent agreement with published values. Additionally, the dynamically forced cantilever principle may possibly improve the sensitivity of some micromechanical cantilever-sensors and it could also be interesting for the design of enhanced micromechanical high frequency mixer filters. Some ideas about are briefly presented.

  15. Application Possibilities and Consequences of Biological Assets and Agricultural Produce Reporting in Accordance with IFRS Principles in the Czech Republic

    Directory of Open Access Journals (Sweden)

    J. Hinke

    2013-12-01

    Full Text Available The Czech national law regulating accounting is not harmonized with International Financial Reporting Standards (IFRS. Because of this, all financial statements compiled according to Czech regulations are not comparable with IFRS statements. International users of accounting information, e.g. potential investors, therefore have problems to find valid information. This article analyzes the evaluation, accounting recording, and reporting of biological assets and agricultural produce in both accounting systems. It illustrates the principal differences, and explains their impact on financial statements information. Based on a case study, the paper recommends how to implement IFRS principles to the accounting system in Czech agriculture enterprises. The authors recommend using income statements with expenses by function, which is not commonly used by Czech entities. The research findings indicate possible changes in the Czech accounting and tax laws, which may lead to a “more true and fair view” of provided accounting information. The proposals should cause that accounting information provided by financial statements compiled according to Czech law would be identical with accounting information in compliance with IFRS principals. A questionnaire survey revealed scepticism of economists agricultural companies to use fair value as the measurement basis for biological assets and agricultural produce.

  16. Molecular evolution of the exon 2 of CHS genes and the possibility of its application to plant phylogenetic analysis

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    The exon 2 of chalcone synthase (CHS) gene is relatively conserved during evolution.In this study,three exon 2 fragments from two species in gymnosperm (Cycas panzhihuaensis,Ginkgo biloba) and seven from four species in angiosperm (Magnolia denudata,Salix babylonica,Nymphaea tetragona,Camellia japonica) have been amplified by PCR from genomic DNA and sequenced.Together with other 73 sequences of CHS collected from EMBL database and literature,these sequences,which embrace 19 families of gymnosperm and angiosperm,have been analyzed for their phylogenetic relations by parsimony method.The result indicated that sequences from the same systematic family usually grouped together except those from Theaceae,Magnoliaceae and Nymphaeaceae.The relative rate test revealed the rate heterogeneity of CHS genes among the families.For the nucleotide substitution the sequences from Asteraceae and Solanaceae evolve faster than those from the other families analyzed while the sequences from Poaceae,Asteraceae and Solanaceae evolve faster for the nonsynonymous substitution.These results suggest that the duplication and extinction events of CHS genes are different among systematic families,therefore it seems impractical to look for orthologous sequences from CHS genes to study plant phylogeny at the family level and/or above.However,it is possible to do so below the family level.

  17. Applicability of the Fermi golden rule and the possibility of low-field runaway transport in nitrides

    Energy Technology Data Exchange (ETDEWEB)

    Komirenko, S.M.; Kim, K.W. [Department of Electrical and Computer Engineering, North Carolina State University, Raleigh, NC (United States); Stroscio, M.A.; Dutta, M. [US Army Research Office, Research Triangle Park, NC (United States)

    2001-07-16

    We investigated electron transport characteristics of wide-band polar semi-conductors with intermediate strength of the electron-phonon interaction. Electron energy loss to the lattice was calculated as a function of electron velocity for various materials in the frameworks of (a) a perturbative approach based on the calculation of scattering rates from Fermi's golden rule and (b) a non-perturbative approach based on the path-integral formalism of Thornber and Feynman. Our results suggest that the standard perturbative treatment can be applied to GaN and AlN despite the relatively strong electron-phonon coupling in this material system, with intercollision times of the order of the period of the phonon oscillation. Our findings also indicate the possibility for unique long-distance runaway transport in nitrides which may occur at the pre-threshold electric fields. The polaron ground-state energy and effective masses are calculated for GaN and AlN as well as for GaAs and Al{sub 2}O{sub 3}. An expression for the Froehlich coupling constant for wurtzites is derived. (author)

  18. The effect of viscosity on impact cratering and possible application to the icy satellites of Saturn and Jupiter

    Science.gov (United States)

    Fink, J.; Gault, D.; Greeley, R.

    1984-01-01

    Impact experiments in Newtonian fluids with a range of viscosities of 0.001 to 60 Pa s demonstrate that transient crater volume and shape depend on target viscosity as well as on gravity. Volume is reduced, and depth-to-diameter ratio is increased for cratering events in which viscosity plays a dominant role. In addition to being affected by target kinematic viscosity, viscous scaling is most strongly influenced by projectile diameter, less strongly by projectile velocity, and least strongly by gravity. In a planetary context, viscous effects can occur for craters formed by small or slow moving impacting bodies, low planetary surface densities, high surface viscosities, and low gravity values; conditions all likely for certain impacts into the icy satellites of Saturn and Jupiter, especially if liquid mantles were still present beneath solid crusts. Age dating based on crater counts and size-frequency distributions for these icy bodies may have to be modified to account for the possibility that viscosity-dominated craters were initially smaller and deeper than their gravity-controlled counterparts.

  19. Use of the asymmetric planar hall resistance of an Fe film for possible multi-value memory device applications.

    Science.gov (United States)

    Yoo, Taehee; Khym, S; Lee, Hakjoon; Lee, Sangyeop; Kim, Shinhee; Shin, Jinsik; Lee, Sanghoon; Liu, X; Furdyna, J K

    2011-07-01

    Systematic planar Hall measurements have been performed on a ferromagnetic Fe film grown on a standard (001) GaAs substrate at room temperature. The angular dependence of the planar Hall effect revealed the presence of both four-fold (cubic) and two-fold (uniaxial) anisotropies in the 7 nm thick Fe film. The dominance of the four-fold symmetric anisotropy, however, provided four magnetic easy axes near the (100) direction, which results in a two step switching phenomenon in the magnetization reversal process. An interesting asymmetric hysteresis loop was observed in the planar Hall resistance (PHR) when the turning point of the field scan is set at the value in the region of the second transition. The intermediate resistance states appearing in the asymmetric PHR loop were understood in terms of mutli-domain structures formed during the second switching of magnetization. Such multi-domain structure of the Fe film showing robust time stability provided additional Hall resistance states, which can be used for multi-valued memory device applications.

  20. The possibility of the application of the zeolyte powders for the construction of the membranes for the carbon dioxide separation

    Directory of Open Access Journals (Sweden)

    Nedeljković Dragutin M.

    2015-01-01

    Full Text Available The task of this work was to construct the mixed matrix membrane based on polymer that could be used for the treatment of the waste gases. Therefore, high permeability for the carbon dioxide and low permeability for other gases commonly present in the industrial combustion waste gases (nitrogen, oxygen, hydrogen, methane are essential. Those membranes belong to the group of dense composite membranes, and mechanism for separation is based on the solution-diffusion mechanism. In this paper, feasibility of the application of poly(ethyleneoxid-copoly(phtalamide was tested. In order to enchase the permeability of carbon dioxide, three different zeolites were incorporated, and in order to improve compatibility between the inorganic particles and polymer chains, n-tetradecyldimethylamonium bromide (NTAB.was added. Three zeolites were with the 2-dimensional pores (IHW, NSI and TER. The best results in carbon dioxide/hydrogen selectivity were obtained with the membrane constructed with PEBAX 1657 and surface treated zeolites, while the better results concerning selectivity were gained with membranes based on the Polyactive. [Projekat Ministarstva nauke Republike Srbnije, br. TR 34011 i br. III 45019

  1. Enhancement of X-ray-induced breaks in DNA bound to molecules containing platinum: a possible application to hadrontherapy.

    Science.gov (United States)

    Kobayashi, K; Frohlich, H; Usami, N; Takakura, K; Le Sech, C

    2002-01-01

    Complexes made of DNA and chloroterpyridine platinum (PtTC) bound to plasmid DNA were placed in aqueous solution and irradiated with monochromatic X rays tuned to the resonant photoabsorption energy of the L(III) shell of the platinum atom. The number of single- and double-strand breaks (SSBs and DSBs) induced by irradiation on a supercoiled DNA plasmid was measured by the production of the circular-nicked and linear forms. To distinguish the contribution of the direct effects of ionization from the indirect effects due to a free radical attack, experiments were also performed in the presence of a hydroxyl free radical scavenger, dimethyl sulfoxide (DMSO). An enhancement of the number of SSBs and DSBs was observed when the plasmids contained the platinum intercalating molecules. A quantitative analysis was made to evaluate the respective contributions of the direct effects (Auger effect) and the indirect effects (free radical attack) to the number of DNA strand breaks. Even when off-resonant X rays were used, the strand break efficiency remained higher than expected based upon the absorption cross section, suggesting that the platinum bound to DNA might be increasing the yield of strand breaks. A mechanism is suggested that involves photoelectrons generated from the ionization of water which efficiently ionize platinum atoms. If this mechanism is correct, then heavy atoms, with a large cross section for ionization by electrons that are bound to the DNA, should behave as a radiosensitizer. This observation may provide insight into understanding the effects of new radiotherapy protocols, related chemotherapeutic agents such as cisplatin, and conventional radiotherapy for the treatment of tumors. A possible way to deliver the dose selectively in a well-defined volume, which uses the properties of the linear energy transfer of atomic ions interacting with matter, is suggested.

  2. New method for surname studies of ancient patrilineal population structures, and possible application to improvement of Y-chromosome sampling.

    Science.gov (United States)

    Manni, Franz; Toupance, Bruno; Sabbagh, Audrey; Heyer, Evelyne

    2005-02-01

    Several studies showed that surnames are good markers to infer patrilineal genetic structures of populations, both on regional and microregional scales. As a case study, the spatial patterns of the 9,929 most common surnames of the Netherlands were analyzed by a clustering method called self-organizing maps (SOMs). The resulting clusters grouped surnames with a similar geographic distribution and origin. The analysis was shown to be in agreement with already known features of Dutch surnames, such as 1) the geographic distribution of some well-known locative suffixes, 2) historical census data, 3) the distribution of foreign surnames, and 4) polyphyletic surnames. Thus, these results validate the SOM clustering of surnames, and allow for the generalization of the technique. This method can be applied as a new strategy for a better Y-chromosome sampling design in retrospective population genetics studies, since the idenfication of surnames with a defined geographic origin enables the selection of the living descendants of those families settled, centuries ago, in a given area. In other words, it becomes possible to virtually sample the population as it was when surnames started to be in use. We show that, in a given location, the descendants of those individuals who inhabited the area at the time of origin of surnames can be as low as approximately 20%. This finding suggests 1) the major role played by recent migrations that are likely to have distorted or even defaced ancient genetic patterns, and 2) that standard-designed samplings can hardly portray a reliable picture of the ancient Y-chromosome variability of European populations.

  3. Observations of Earthquake-Generated T-Waves in the South China Sea: Possible Applications for Regional Seismic Monitoring

    Directory of Open Access Journals (Sweden)

    Bor-Shouh Huang

    2013-01-01

    Full Text Available We present a detailed study of T-waves originating from earthquakes in the South China Sea region, near the Indochina Peninsula and Luzon islands which were recorded by a broadband seismic station at Nansha Island. Most of these T-waves appear to have been the source originating from earthquakes with epicentral distances greater than 600 km from this station. The T-waves in this region were identified via their apparent stable measured velocities of about 1.45 km s-1, and represent the first reported T-waves and the first T-waves observed from an island station in the South China Sea. However, during the period of analysis (November 2004 to December 2005 additional earthquakes also occurred beyond the South China Sea region, but in these instances, any associated T-waves were not picked up by the station at Nansha Island. An analysis of T-wave travel times reveals the possible locations of the P-wave to T-wave transitions at the ocean to crust interface were presumably situated near the earthquake source side. Our results indicate that the Sound Fixing and Ranging (SOFAR channel is well developed in the South China Sea region. Ultimately, developing a solid understanding of the effective transmission of T-waves through the ocean may provide new opportunities for detecting and locating small earthquakes which would be useful for both seismic monitoring and in helping to predict and reduce the damaging effects of earthquakes and tsunamis in the SouthChina Sea region.

  4. Observations of Earthquake-Generated T-Waves in the South China Sea: Possible Applications for Regional Seismic Monitoring

    Directory of Open Access Journals (Sweden)

    Bor-Shouh Huang

    2013-01-01

    Full Text Available We present a detailed study of T-waves originating from earthquakes in the South China Sea region, near the Indochina Peninsula and Luzon islands which were recorded by a broadband seismic station at Nansha Island. Most of these T-waves appear to have been the source originating from earthquakes with epicentral distances greater than 600 km from this station. The T-waves in this region were identified via their apparent stable measured velocities of about 1.45 km s-1, and represent the first reported T-waves and the first T-waves observed from an island station in the South China Sea. However, during the period of analysis (November 2004 to December 2005 additional earthquakes also occurred beyond the South China Sea region, but in these instances, any associated T-waves were not picked up by the station at Nansha Island. An analysis of T-wave travel times reveals the possible locations of the P-wave to T-wave transitions at the ocean to crust interface were presumably situated near the earthquake source side. Our results indicate that the Sound Fixing and Ranging (SOFAR channel is well developed in the South China Sea region. Ultimately, developing a solid understanding of the effective transmission of T-waves through the ocean may provide new opportunities for detecting and locating small earthquakes which would be useful for both seismic monitoring and in helping to predict and reduce the damaging effects of earthquakes and tsunamis in the South China Sea region.

  5. Novel bispidine ligands with a possible application in nuclear medicine; Neue Bispidin-Liganden mit potenzieller Anwendung in der Nuklearmedizin

    Energy Technology Data Exchange (ETDEWEB)

    Rudolf, Henning

    2013-10-24

    Due to our current way of life and the environmental influences we are exposed in the industrial nations, cancer diseases turn out to be a more and more serious threat to our civilization. The ongoing research during the last decades leads to a better insight in cancer diseases and enables an earlier recognition of developing carcinoma. The detection of pathological tissue changes at an early stage increases the patients' chances of cure. Magnetic resonance tomography (MRT) and computed tomography (CT) as well as radiopharmaceutically assisted imaging techniques, like positron emission tomography (PET) and scintigraphy are an indispensable clinical tool in the oncological early diagnosis. By the development of multimodality imaging agents that combine the benefits of several imaging techniques, the early recognition of tumors can be more efficient and in consequence a matching therapy can be applied. This thesis deals with the synthesis of novel bispidine based ligands and their transition metal complexes as potential mono- and bimodal imaging agents for a {sup 64}Cu-assisted radiopharmaceutical application in positron emission tomography (PET) and optical imaging (OI). The synthesized ligands L and L{sup OH} are offering the opportunity to build up a ruthenium(II) polypyridine complex by one of the ligand's donor sets, to act as a fluorescence dye for optical imaging (OI), and to coordinate {sup 64}Cu{sup II} by the ligand's vacant cavity for positron emission tomography (PET). The Ru{sup II} complex exhibits two different fluorescence activities with two different lifetimes and only one of the two fluorescences is quenched by subsequent complexation of Cu{sup II}. The calculated Cu{sup II} stability constant of L and L{sup OH} is similar to that of the isomeric ligand N{sub 2}py{sub 2} which has been already evaluated as a {sup 64}Cu-radiotracer. Further transition metal complexes of Fe{sup II}, Fe{sup III} and Mn{sup II} are dealing with

  6. {alpha}-{alpha} interaction reexamined in the context of the Sao Paulo potential: possible applications in astrophysics?

    Energy Technology Data Exchange (ETDEWEB)

    Gasques, L.R.; Chamon, L.C.; Botero, D.F.M. [Universidade de Sao Paulo (DFN/USP), SP (Brazil). Dept. de Fisica Nuclear; Alves, L.F.M. [Instituto Federal de Educacao, Ciencia e Tecnologia (Brazil); Carlson, B.V. [Instituto Tecnologico de Aeronautica (CTA/ITA), Sao Jose dos Campos, SP (Brazil). Dept. de Fisica Nuclear; Rossi Junior, E.S. [Centro Universitario FIEO(UNIFIEO), SP (Brazil)

    2012-07-01

    Full text: We have analyzed a large set of {alpha}-{alpha} elastic scattering data for bombarding energies ranging from 0.6 to 29.5 MeV. The complete lack of open reaction channels at these somehow low energies results in a vanishing imaginary part for the optical interaction. This characteristic makes the {alpha}-{alpha} reaction particularly interesting as the corresponding elastic scattering cross sections and phase shifts become very sensitive to the real part of the interaction. The data were analyzed within the context of the velocity-dependent Sao Paulo potential, which is a successful theoretical model for the description of heavy-ion reactions from sub-barrier to intermediate energies. We have shown that, even in this low energy region, the velocity dependence of the Sao Paulo potential model is a necessary ingredient for describing the data. Despite the reasonable description obtained with the Sao Paulo potential, the analyses indicate the necessity of an additional weak dependence of the interaction on the angular momentum. These important characteristics open the possibility for studying reactions with astrophysical interested. In particular, predictions of the astrophysical S-factor for the {sup 12}C({alpha},{gamma}) reaction will be presented. The understanding of the reaction rate for the {alpha}-capture process by a {sup 12}C nucleus is a crucial ingredient for predicting the stellar helium burning and the subsequent fate of stars as this reaction determines the ratio of carbon to oxygen towards the end of the Red Giants phase. It is well known that low mass stars evolve to White Dwarfs and this ratio determines the final abundance composition in White Dwarf matter and sets the trigger conditions for type Ia supernova explosions. The carbon-oxygen ratio also dictates the subsequent sequence of burning processes during the final stages of stellar evolution for massive stars. Thus, it has a key role in the determination of the abundance composition in

  7. Remote possibilities

    Energy Technology Data Exchange (ETDEWEB)

    Butler, M. [Inmarsat (United Kingdom)

    2004-08-01

    The paper examines how a new generation of small mobile satellite data services are delivering possibilities for competitive advantage in the coal industry. Inmarsat has developed a range of products that bring access to high-speed, secure IP data from locations not supported by terrestrial/cellular networks or fixed satellite services. It launched its regional broadband global area network BGAN service in late 2002. The sizing of a small notebook PC and light-weight, the new device brings secure access to corporate networks and databases, email and the internet at speeds of up to 144 Kbit/s. The next generation of Inmarsat satellites will enable the BGAN service to provide communications at speeds up to 432 Kbit/s.

  8. Possibility Intuitionistic Fuzzy Soft Set

    Directory of Open Access Journals (Sweden)

    Maruah Bashir

    2012-01-01

    Full Text Available Possibility intuitionistic fuzzy soft set and its operations are introduced, and a few of their properties are studied. An application of possibility intuitionistic fuzzy soft sets in decision making is investigated. A similarity measure of two possibility intuitionistic fuzzy soft sets has been discussed. An application of this similarity measure in medical diagnosis has been shown.

  9. Perspectives and possible applications of the rubber hand and virtual hand illusion in non-invasive rehabilitation: technological improvements and their consequences.

    Science.gov (United States)

    Christ, Oliver; Reiner, Miriam

    2014-07-01

    This review introduces theoretical aspects of the rubber hand illusion (RHI) and virtual hand illusion (VHI), and discusses their possible clinical applications. It also presents technical improvements regarding the realization of the RHI and VHI and their relation to rehabilitation issues. There is presently little evidence describing the value of the RHI and VHI as indices in the diagnosis or treatment of different pathologies, likely because of a lack of standardization in reporting the results of RHI and VHI studies. In contrast, a new emerging "out-of-body illusion" appears to be an interesting new approach; however, as in RHI and VHI, there are additional consequences regarding its application in clinical settings because of its technological demands. This review considers the acceptance of technology and the realization of immersion/presence in the context of virtual rehabilitation.

  10. Windpower utilization possibilities

    Science.gov (United States)

    Hoetzel, C.

    1982-01-01

    The possibilities of windpower utilization for mechanical pumps, electric generators, mechanical water vortex pumps, and heat pumps are reviewed. Application possibilities can be realized by windpower systems of different size. It must however be determined for which purpose and for which power range they are used. The site and the concomitant wind potential is of utmost importance. Small units in the 10 kW power range are very interesting for autonomous or semiautonomous energy supply.

  11. [The currently available possibilities for the application of photogrammetry in the forensic medical expertise of the blood stains at the scene of the crime].

    Science.gov (United States)

    Fetisov, V A; Makarov, I Yu; Gusarov, A A; Lorents, A S; Smirenin, S A; Stragis, V B

    2017-01-01

    The study of blood stains retained at the scene of the crime is of crucial importance for the preliminary inquiry. The present article is focused on the analysis of the possibilities and prospects for the use of photogrammetry (PM) as exemplified by the foreign expert practice of the blood stains examination at the site of the event. It is shown that the results of the application of digital photogrammetry in addition to the traditional methods of morphological investigations enables the forensic medical experts to reconstruct a number of unique features and circumstances that accompanied the commission of a crime at the site of the event. Such PM techniques supplemented by the ballistic analysis of the blood splatter and droplet trajectories provides additional evidence that allows the forensic medical experts to reconstruct the scene of the crime including the pose and position of the victim at the moment of causing injury. Moreover, these data make it possible to determine the maximum number and the sequence of injurious impacts (blows). The authors discuss the advantages and relative disadvantages of the application of the photogrammetric technique in the routine practical expert work. It is emphasized that the published decision making algorithms provide the specialists in various disciplines and professional experts with the ready-made technological tools for obtaining the additional criteria for the objective improvement of the quality of the studies they carry out and for the enhancement of the value of expert conclusions. It is concluded that the application of the modern photogrammetric technologies can be recommended for the solution of the applied forensic medical problems and conducting the relevant expert research.

  12. Improved methods for the generation of 24.5 keV neutron beams with possible application to boron neutron capture therapy

    Science.gov (United States)

    Constantine, G.; Baker, L. J.; Taylor, N. P.

    1986-09-01

    The production of epithermal neutron beams, filtered to provide a spectrum in which a small energy range predominates, is of importance for radiobiological research and in the development and calibration of instruments for monitoring intermediate energy neutrons. The penetration characteristics of intermediate energy neutrons in tissue lead to the possibility of application in the field of neutron capture therapy if beams of sufficient intensity and adequate spectral properties can be generated. In this paper methods of utilising the 24.5 keV antiresonance in the iron neutron cross section are described, and the DENIS (depth enhanced neutron intense source) principle by which beam intensities may be optimised is explained. Calculations and experimental measurements in an in-core facility in the DIDO reactor at Harwell have indicated that a DENIS scatterer can achieve a 6-fold improvement in 24.5 keV beam intensity compared with a conventional titanium disc scatterer.

  13. Color-coded multilayer photopatterned microstructures using lanthanide (III) ion co-doped NaYF{sub 4} nanoparticles with upconversion luminescence for possible applications in security

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Won Jin; Nyk, Marcin; Prasad, Paras N [Department of Chemistry, Institute for Lasers, Photonics and Biophotonics, University at Buffalo, State University of New York, Buffalo, NY 14260 (United States)], E-mail: pnprasad@buffalo.edu

    2009-05-06

    We report a method for fabricating predefined photopatterns of upconversion nanophosphors using a chemical amplification reaction for direct writing of films with multilayer color-coded patterning for security applications. To photopattern the nanocrystal film we have synthesized rare-earth ion (Er{sup 3+}/Yb{sup 3+} or Tm{sup 3+}/Yb{sup 3+}) co-doped sodium yttrium fluoride ({alpha}-NaYF{sub 4}) nanophosphors and functionalized the nanocrystal surfaces by incorporation of a photopatternable ligand such as t-butoxycarbonyl (t-BOC). The surface modification allows photopatterning of the nanophosphor solid state film. Furthermore, upconversion nanophosphors show a nearly quadratic dependence of the upconversion photoluminescence (PL) intensity on the excitation light power, and tailoring of the PL wavelength is possible by changing the lanthanide ions. We have demonstrated the capability of anchoring nanophosphors at desirable locations by a photolithography technique. The photopatterned films exhibit fixed nanophosphor structures clearly identifiable by strong upconversion photoluminescence under IR illumination which is useful for a number of applications in security.

  14. Possible Application of Raman Microspectroscopy to Verify the Interstitial Cystitis Diagnosis after Potassium Sensitivity Test: Phenylalanine or Tryptophan as a Biomarker

    Directory of Open Access Journals (Sweden)

    Tzu-Feng Hsieh

    2007-01-01

    Full Text Available There is lack of a worldwide standard technique for clinical diagnosis of interstitial cystitis (IC. Raman spectroscopy with higher specificity and sensitivity has been extensively used to act as a non-destructive analytical technique without special sample preparation. In this preliminary study, possible use of Raman microspectroscopy as an IC diagnostic tool was attempted. Twenty-two participants were screened by clinical features, history, urodynamic evaluations and potassium sensitivity test (PST. The freeze-dried water samples voided from all the participants after PST were directly determined by using a confocal Raman microspectroscopy to search the biomarker. Participants with or without IC symptom were separated into control and clinical groups, according to the above screening. The participants in the clinical group were further divided into mild and severe subgroups by PST. The symptom of urinary pain and urgency was significant difference between the mild and severe subgroups (p < 0.05. A significant increase in urinary frequency but a marked reduction in bladder capacity, maximum cystometric capacity and maximum voiding flow rate were obtained for clinical group of IC participants, as compared with the result of control group (p < 0.05. By using Raman microspectroscopic determination, the band near 1003 or 1005 cm−1 assigned to phenylalanine was respectively detected from the freeze-dried water sample of control group or mild subgroup, but the band at 1010 cm−1 due to tryptophan was found in the freeze-dried water sample of severe subgroup. The result of this preliminary study first suggests a possible application of Raman microspectroscopy to strongly certify the results of PST for IC diagnosis. Phenylalanine or tryptophan might be acted as a biomarker to assist the diagnosis of IC after PST. Particularly, the appearance of tryptophan might be used to discriminate the severity of IC symptom.

  15. Current use and possible future applications of the magnetization transfer technique in neuroradiology; Aktuelle Anwendungen und moegliche zukuenftige Applikationen der Magnetisierungstransfer-Technik in der Neuroradiologie

    Energy Technology Data Exchange (ETDEWEB)

    Haehnel, S.; Jost, G.; Sartor, K. [Abt. Neuroradiologie, Neurologische Klinik, Universitaetsklinikum Heidelberg (Germany); Knauth, M. [Abt. Neuroradiologie, Universitaetsklinikum Goettingen (Germany)

    2004-02-01

    Magnetization transfer (MT) imaging is a special MR technique used for selective suppression of the MR signal of protons bound on macromolecules. The most important applications in neuroradiology are (1) detection of subtle changes in otherwise normal-appearing cerebral white matter, for instance in multiple sclerosis (MS), Wallerian degeneration, and hydrocephalus, (2) differentiation of white matter lesions with high signal on T{sub 2}-weighted MR-images, like MS plaques, brain infarctions, and brain edema, (3) follow-up of cerebral white matter diseases using volumetric MT techniques, and (4) improvement in delineating of contrast enhancing brain lesions, such as cerebral metastases. We describe the physical rationale of the MT technique and present the most important current and possible future applications of MT imaging to answer clinical and scientific questions in neuroradiology. (orig.) [German] Die Magnetisierungstransfer-(MT)-Technik ist ein spezielles MRT-Verfahren, mit dem selektiv das MR-Signal der an Makromolekuele gebundenen Protonen unterdrueckt werden kann. Die wichtigsten Anwendungen dieser Technik in der Neuroradiologie sind der Nachweis von subtilen Veraenderungen in ansonsten normal erscheinender weisser Hirnsubstanz, wie z.B. bei Multipler Sklerose (MS), Waller'scher Degeneration und Hydrozephalus, die Differenzierung von Laesionen der weissen Substanz, die durchgaengig hohes Signal auf T{sub 2}-gewichteten MRT-Aufnahmen zeigen, wie z.B. MS-Plaques, Hirninfarkte oder Hirnoedem, die Verlaufskontrolle von Erkrankungen der weissen Substanz mit der volumetrischen MT-Technik, und die Verbesserung der Abgrenzbarkeit kontrasmittelaufnehmender Hirnlaesionen wie Hirnmetastasen. Wir beschreiben die MR-physikalischen Grundlagen der MT-Technik und stellen die wesentlichen aktuellen und moeglichen zukuenftigen Anwendungen zur Beantwortung klinischer und wissenschaftlicher Fragestellungen in der Neuroradiologie vor. (orig.)

  16. Application of passive sampling devices based on multi-walled carbon nanotubes for the isolation of selected pharmaceuticals and phenolic compounds in water samples - possibilities and limitations.

    Science.gov (United States)

    Jakubus, Aleksandra; Tyma, Magdalena; Stepnowski, Piotr; Paszkiewicz, Monika

    2017-03-01

    Nowadays, carbon nanotubes, as commercially available materials, have attracted great attention because of their unique physicochemical properties, especially their strong adsorption abilities. This paper deals with the possibilities and limitations of the application of multi-walled carbon nanotubes as an alternative sorbent in passive sampling devices for the isolation of selected pharmaceuticals and phenolic compounds directly in water samples. Compounds with different properties, including sulfapyridine, sulfamethoxazole, carbamazepine, p-nitrophenol, 17-β-estradiol, 3,5-dichlorophenol and diclofenac were selected as model compounds. Firstly, the influence of several parameters on the extraction efficiency was defined, then the matrix effect and standard validation parameters were established. Under optimized conditions, the proposed analytical methods exhibited good validation parameters, including excellent linearity with R(2) >0.999, the LODs were found to be between 0.01-0.5μgL(-1) and the LOQ ranged from 0.05 to 1.5μgL(-1). Recovery values obtained for model compounds were 79,8±0.2% for sulfapyridine, 41,5±0.1% for sulfamethoxazole, 96,6±1,5% for carbamazepine, 70,5±0.1% for p-nitrophenol, 77,1±0.5% for 17-β-estradiol, 103,1±1.8% for 3,5-dichlorophenol and 76,3±1.4% for diclofenac. This study provides useful data regarding the sorption process on MWCNTs and definitely evaluates the application potential of these types of sorbents in passive sampling devices.

  17. The CMT-process and its possible applications, especially joining of steel with aluminium; Der CMT - Prozess und seine Moeglichkeiten, im speziellen das Fuegen von Stahl mit Aluminium

    Energy Technology Data Exchange (ETDEWEB)

    Bruckner, J.; Himmelbauer, K.; Hackl, H. [Fronius International GmbH, Wels (Austria)

    2004-07-01

    Knowing how to weld dissimilar metals is becoming more and more important. One reason is that it's often impossible for one material to provide the optimum chemical, physical, and mechanical characteristics needed for an application. For this reason, as well as cost efficiency, technology specialists are experimenting with different joining processes to weld bimetal joints optimally. A reliable method of joining the two most commonly used metals, steel and aluminum, would make it possible to make these joints in several applications. On one hand, aluminum is becoming increasingly more important in the automotive industry because of its good processing and performance characteristics and because it's lightweight, which results in lower fuel consumption. Given today's heightened need to decrease energy consumption, aluminum is a major player in modern-day mechanical engineering. On the other hand, steel continues to dominate many fields of engineering, a fact underlined by the development of high-strength and superhigh-strength steels. When different metals are joined, each metal's features should be considered. It's important to pay attention to the chemical and physical properties-such as the corrosion behavior and thermal expansion coefficient-and to atomic properties, such as the lattice constant and type of crystalline lattice. Processes typically used to join dissimilar metals are bonding, riveting, or clinching, which essentially have no influence on the metals' atomic properties. Another method, thermal joining, can shorten joining time, produce tight seams, and provide high strength. (orig.)

  18. A multidisciplinary approach for the study of the effects of active tectonics along the North Anatolian fault zone: possibilities for the application of the electrical self potential method

    Directory of Open Access Journals (Sweden)

    W. Balderer

    1994-06-01

    Full Text Available The aims of this joint interdisciplinary project “Marmara” of ETH Zurich and the Istanbul Technical University (ITO are to study the effects of active tectonics as evidenced by geology, geodesy and seismology on hydrogeology and geothermics in selected areas along the North Anatolian fault zone. Within the framework of this project thermal water systems in seven different areas have been investigated or are under investigation up to now (SchindIer et al., 1993. For three study areas along the North Anatolian fault zone (from east to west of Kuzuluk/Adapazari, Bursa and of Canakkale the investigations with respect to the geological and hydrogeological features are complete. The now possible hydrogeological characterisation shows encouraging possibilities for the application of new methods like the electrical self potential method for the following reasons: 1 a fully interdisciplinary approach, including seismic survey with especially conceived network, geodetic survey to investigate tectonic movements by the GPS method, geothermic survey combined with geological mapping and hydrogeological investigations of normal mineral and thermal waters; 2 groundwaters of very different chemical and isotopical composition e.g.: Ca-HCO3-type thermal waters of up to 82 °C temperature and total mineralisation of 500 mg/I to 1500 mg/I in the Bursa area, Na-HCO3-type cold mineral waters of up to 2500 mg/I to thermal waters of same mineralisation of up to 80 °C temperature, containing large amounts of CO2 of up to 1 l per 1 kg of water (at surface conditions in the Kuzuluk area and Na-Cl-type waters presenting real thermal brines of up to 65 000 mg/I of total mineralisation and temperatures of up to 100 °C in the Canakkale area; 3 distinct types of hydrodynamic flow regime in areas of different geological and tectonic structure. Based on the results of the investigations within these areas the possibilities of further studies including self potential methods

  19. Effects of clove oil-phospholipid mixtures on rheology of gum tragacanth - possible application for surfactant action on mucus gel simulants.

    Science.gov (United States)

    Banerjee, R; Puniyani, R R

    2000-01-01

    The present study evaluates the effectiveness of specialised biomaterials consisting of clove oil- phospholipid mixtures as possible substitute surfactants in diseases of altered mucus viscosity by studying their effect on the viscosity of mucus gel simulants in vitro. Test surfactants consisting of phospholipid-clove oil mixtures in the ratio of 1 part of oil to 9 parts of phospholipid were prepared. The phospholipids used were dipalmitoyl phosphatidylcholine (PC), phosphatidylethanolamine (PE) and phosphatidylglycerol (PG) and binary mixtures of PC: PE and PC: PG in the ratio of 2 parts of PC to 3 parts of PE or PG. The effects of the phospholipid-clove oil mixtures on the viscosity of mucus gel simulant (MGS: a polymeric gel consisting predominantly of gum tragacanth and simulating respiratory mucus), was studied by application of steady shear rates ranging from 0.512 to 51.2/s in a concentric cylinder viscometer at 37 degrees C. The change in MGS viscosity, after incubation with surfactants, was found to have a non-Newtonian character and to follow the power law model with R2 values >0.8. The addition of clove oil-phospholipid mixtures caused a decrease in the MGS viscosity when compared with the effect of the phospholipid alone at low shear rates in case of PC, PG and PCPG. The combination of PC : PG with clove oil caused ratios of change in MGS viscosity rheology.

  20. A PCR-based sex determination method for possible application in caprine gender selection by simultaneous amplification of the Sry and Aml-X genes.

    Science.gov (United States)

    Phua, Alice Choon Yen; Abdullah, Ramli Bin; Mohamed, Zulqarnain

    2003-08-01

    Sex determination of livestock is performed to achieve the objectives of livestock breeding programmes. Techniques for sex determination have evolved from karyotyping to detecting Y-specific antigens and recently to the polymerase chain reaction (PCR), which appears to be the most sensitive, accurate, rapid and reliable method to date. In this study, a PCR-based sex determination method for potential application in goat breeding programmes was developed. Primers were designed to amplify a portion of the X amelogenin gene (Aml-X) on the X chromosome to give a 300 bp product and Sry gene on the Y chromosome to give a 116 bp product. PCR optimization was performed using DNA template extracted from a whole blood sample of Jermasia goats (German Fawn x Katjang) of both sexes. It was possible to identify the sex chromosomes by amplifying both male- and female-specific genes simultaneously in a duplex reaction with males yielding two bands and females yielding one band. The Aml-X primer set, which served as an internal control primer, did not interfere with amplification of the Y-specific sequence even when a low amount of DNA (1 ng) was used. The duplex reaction subjected to a blind test showed 100% (14/14) concordance, proving its accuracy and reliability. The primer sets used were found to be highly specific and were suitable for gender selection of goats.

  1. Quantum chemical calculations and spectroscopic measurements of spectroscopic and thermodynamic properties of given uranyl complexes in aqueous solutions with possible environmental and industrial applications

    Directory of Open Access Journals (Sweden)

    Višňak Jakub

    2016-01-01

    Full Text Available A brief introduction into computational methodology and preliminary results for spectroscopic (excitation energies, vibrational frequencies in ground and excited electronic states and thermodynamic (stability constants, standard enthalpies and entropies of complexation reactions properties of some 1:1, 1:2 and 1:3 uranyl sulphato- and selenato- complexes in aqueos solutions will be given. The relativistic effects are included via Effective Core Potential (ECP, electron correlation via (TDDFT/B3LYP (dispersion interaction corrected and solvation is described via explicit inclusion of one hydration sphere beyond the coordinated water molecules. We acknowledge limits of this approximate description – more accurate calculations (ranging from semi-phenomenological two-component spin-orbit coupling up to four-component Dirac-Coulomb-Breit hamiltonian and Molecular Dynamics simulations are in preparation. The computational results are compared with the experimental results from Time-resolved Laser-induced Fluorescence Spectroscopy (TRLFS and UV-VIS spectroscopic studies (including our original experimental research on this topic. In case of the TRLFS and UV-VIS speciation studies, the problem of complex solution spectra decomposition into individual components is ill-conditioned and hints from theoretical chemistry could be very important. Qualitative agreement between our quantum chemical calculations of the spectroscopic properties and experimental data was achieved. Possible applications for geochemical modelling (e.g. safety studies of nuclear waste repositories, modelling of a future mining site and analytical chemical studies (including natural samples are discussed.

  2. Quantum chemical calculations and spectroscopic measurements of spectroscopic and thermodynamic properties of given uranyl complexes in aqueous solutions with possible environmental and industrial applications

    Science.gov (United States)

    Višňak, Jakub; Sobek, Lukáš

    2016-11-01

    A brief introduction into computational methodology and preliminary results for spectroscopic (excitation energies, vibrational frequencies in ground and excited electronic states) and thermodynamic (stability constants, standard enthalpies and entropies of complexation reactions) properties of some 1:1, 1:2 and 1:3 uranyl sulphato- and selenato- complexes in aqueos solutions will be given. The relativistic effects are included via Effective Core Potential (ECP), electron correlation via (TD)DFT/B3LYP (dispersion interaction corrected) and solvation is described via explicit inclusion of one hydration sphere beyond the coordinated water molecules. We acknowledge limits of this approximate description - more accurate calculations (ranging from semi-phenomenological two-component spin-orbit coupling up to four-component Dirac-Coulomb-Breit hamiltonian) and Molecular Dynamics simulations are in preparation. The computational results are compared with the experimental results from Time-resolved Laser-induced Fluorescence Spectroscopy (TRLFS) and UV-VIS spectroscopic studies (including our original experimental research on this topic). In case of the TRLFS and UV-VIS speciation studies, the problem of complex solution spectra decomposition into individual components is ill-conditioned and hints from theoretical chemistry could be very important. Qualitative agreement between our quantum chemical calculations of the spectroscopic properties and experimental data was achieved. Possible applications for geochemical modelling (e.g. safety studies of nuclear waste repositories, modelling of a future mining site) and analytical chemical studies (including natural samples) are discussed.

  3. Meningococcal Antigen Typing System Development and Application to the Evaluation of Effectiveness of Meningococcal B Vaccine and Possible Use for Other Purposes

    Directory of Open Access Journals (Sweden)

    Alexander Domnich

    2015-01-01

    Full Text Available Development of the 4-component meningococcal serogroup B vaccine (4CMenB has required new assays for the reliable evaluation of the expression and cross-reactivity of those specific antigen variants that are predicted to be targeted by bactericidal antibodies elicited by the vaccine in different isolates. Existing laboratory techniques, such as multilocus sequence typing, are poorly suited to this purpose, since they do not provide information on the contribution of single vaccine components and therefore cannot be applied to estimate the potential coverage of the multicomponent vaccine. The hSBA, the only correlate of protection against invasive meningococcal disease accepted thus far, cannot conveniently be used to test large number of strains. To overcome these issues, the meningococcal antigen typing system (MATS has been specifically developed in order to predict 4CMenB coverage of individual meningococcus serogroup B strains. To date, MATS has proved advantageous for several reasons, including its ability to assess both qualitative and quantitative aspects of surface antigens of single strains in a highly reproducible, rapid, and resource-saving manner, while its shortcomings include a possible underestimation of 4CMenB coverage and the use of pooled sera to calculate the positive bactericidal threshold. This paper provides an overview of MATS development and its field application.

  4. Meningococcal Antigen Typing System Development and Application to the Evaluation of Effectiveness of Meningococcal B Vaccine and Possible Use for Other Purposes.

    Science.gov (United States)

    Domnich, Alexander; Gasparini, Roberto; Amicizia, Daniela; Boccadifuoco, Giuseppe; Giuliani, Marzia Monica; Panatto, Donatella

    2015-01-01

    Development of the 4-component meningococcal serogroup B vaccine (4CMenB) has required new assays for the reliable evaluation of the expression and cross-reactivity of those specific antigen variants that are predicted to be targeted by bactericidal antibodies elicited by the vaccine in different isolates. Existing laboratory techniques, such as multilocus sequence typing, are poorly suited to this purpose, since they do not provide information on the contribution of single vaccine components and therefore cannot be applied to estimate the potential coverage of the multicomponent vaccine. The hSBA, the only correlate of protection against invasive meningococcal disease accepted thus far, cannot conveniently be used to test large number of strains. To overcome these issues, the meningococcal antigen typing system (MATS) has been specifically developed in order to predict 4CMenB coverage of individual meningococcus serogroup B strains. To date, MATS has proved advantageous for several reasons, including its ability to assess both qualitative and quantitative aspects of surface antigens of single strains in a highly reproducible, rapid, and resource-saving manner, while its shortcomings include a possible underestimation of 4CMenB coverage and the use of pooled sera to calculate the positive bactericidal threshold. This paper provides an overview of MATS development and its field application.

  5. Estimation of PSD Shifts for High-Resolution Metrology of Thickness Micro-Changes with Possible Applications in Vessel Walls and Biological Membrane Characterization

    Science.gov (United States)

    Ramos, Antonio; Bazán, Ivonne; Negreira, Carlos; Brum, Javier; Gómez, Tomás; Calás, Héctor; Ruiz, Abelardo; de la Rosa, José Manuel

    2012-01-01

    Achieving accurate measurements of inflammation levels in tissues or thickness changes in biological membranes (e.g., amniotic sac, parietal pleura) and thin biological walls (e.g., blood vessels) from outside the human body, is a promising research line in the medical area. It would provide a technical basis to study the options for early diagnosis of some serious diseases such as hypertension, atherosclerosis or tuberculosis. Nevertheless, achieving the aim of non-invasive measurement of those scarcely-accessible parameters on patient internal tissues, currently presents many difficulties. The use of high-frequency ultrasonic transducer systems appears to offer a possible solution. Previous studies using conventional ultrasonic imaging have shown this, but the spatial resolution was not sufficient so as to permit a thickness evaluation with clinical significance, which requires an accuracy of a few microns. In this paper a broadband ultrasonic technique, that was recently developed by the authors to address other non-invasive medical detection problems (by integrating a piezoelectric transducer into a spectral measuring system), is extended to our new objective; the aim is its application to the thickness measurement of sub-millimeter membranes or layers made of materials similar to some biological tissues (phantoms). The modeling and design rules of such a transducer system are described, and various methods of estimating overtones location in the power spectral density (PSD) are quantitatively assessed with transducer signals acquired using piezoelectric systems and also generated from a multi-echo model. Their effects on the potential resolution of the proposed thickness measuring tool, and their capability to provide accuracies around the micron are studied in detail. Comparisons are made with typical tools for extracting spatial parameters in laminar samples from echo-waveforms acquired with ultrasonic transducers. Results of this advanced measurement

  6. Estimation of PSD Shifts for High-Resolution Metrology of Thickness Micro-Changes with Possible Applications in Vessel Walls and Biological Membrane Characterization

    Directory of Open Access Journals (Sweden)

    Abelardo Ruiz

    2012-11-01

    Full Text Available Achieving accurate measurements of inflammation levels in tissues or thickness changes in biological membranes (e.g., amniotic sac, parietal pleura and thin biological walls (e.g., blood vessels from outside the human body, is a promising research line in the medical area. It would provide a technical basis to study the options for early diagnosis of some serious diseases such as hypertension, atherosclerosis or tuberculosis. Nevertheless, achieving the aim of non-invasive measurement of those scarcely-accessible parameters on patient internal tissues, currently presents many difficulties. The use of high-frequency ultrasonic transducer systems appears to offer a possible solution. Previous studies using conventional ultrasonic imaging have shown this, but the spatial resolution was not sufficient so as to permit a thickness evaluation with clinical significance, which requires an accuracy of a few microns. In this paper a broadband ultrasonic technique, that was recently developed by the authors to address other non-invasive medical detection problems (by integrating a piezoelectric transducer into a spectral measuring system, is extended to our new objective; the aim is its application to the thickness measurement of sub-millimeter membranes or layers made of materials similar to some biological tissues (phantoms. The modeling and design rules of such a transducer system are described, and various methods of estimating overtones location in the power spectral density (PSD are quantitatively assessed with transducer signals acquired using piezoelectric systems and also generated from a multi-echo model. Their effects on the potential resolution of the proposed thickness measuring tool, and their capability to provide accuracies around the micron are studied in detail. Comparisons are made with typical tools for extracting spatial parameters in laminar samples from echo-waveforms acquired with ultrasonic transducers. Results of this advanced

  7. Study of the Ni-NiAl{sub 2}O{sub 4}-YSZ cermet for its possible application as an anode in solid oxide fuel cells

    Energy Technology Data Exchange (ETDEWEB)

    Reyes-Rojas, A [Centro de Investigacion en Materiales Avanzados SC, Miguel de Cervantes 120, Complejo Industrial Chihuahua, Chihuahua (Mexico); Universidad Autonoma del Estado de Mexico, Facultad de Quimica, Toluca (Mexico); Esparza-Ponce, H E [Centro de Investigacion en Materiales Avanzados SC, Miguel de Cervantes 120, Complejo Industrial Chihuahua, Chihuahua (Mexico); Reyes-Gasga, J [Universidad Nacional Autonoma de Mexico, Instituto de Fisica, Mexico DF (Mexico)

    2006-05-17

    Nanocrystalline Ni-NiAl{sub 2}O{sub 4}-YSZ cermet with a possible application as anode in solid oxide fuel cells (SOFCs) has been developed. The powders were prepared by using an alternative solid-state method that includes the use of nickel acetylacetonate as an inorganic precursor to obtain a highly porous material after sintering at 1400 {sup o}C and oxide reduction (NiO -Al{sub 2}O{sub 3}-YSZ {yields} Ni-NiAl{sub 2}O{sub 4}-YSZ) at 800 {sup o}C for 8 h in a tubular reactor furnace using 10% H{sub 2}/N{sub 2}. Eight samples with 45% Ni and 55% Al{sub 2}O{sub 3}-YSZ in concentrations of Al{sub 2}O{sub 3} oxides from 10 to 80 wt% of were mixed to obtain the cermets. The obtained material was compressed using unidirectional axial pressing and calcinations from room temperature to 800 {sup o}C. Good results were registered using a heating rate of 1 {sup o}C min{sup -1} and a special ramp to avoid anode cracking. Thermal expansion, electrical conductivity, and structural characterization by thermo-mechanical analyser (TMA) techniques/methods, the four-point probe method for conductivity, scanning electron microscopy (SEM), x-ray energy dispersive spectroscopy (EDS), x-ray diffraction (XRD), and the Rietveld method were carried out. Cermets in the range 5.5 to 11% Al{sub 2}O{sub 3} present a crystal size around 200 nm. An inversion degree (I) in the NiAl{sub 2}O{sub 4} spinel structure of the cermets Ni-NiAl{sub 2}O{sub 4}-YSZ was found after the sintering and reduction processes. Good electrical conductivity and thermal expansion coefficient were obtained for the cermet with 12 wt% of spinel structure formation.

  8. Possible future HERA analyses

    CERN Document Server

    Geiser, Achim

    2015-01-01

    A variety of possible future analyses of HERA data in the context of the HERA data preservation programme is collected, motivated, and commented. The focus is placed on possible future analyses of the existing $ep$ collider data and their physics scope. Comparisons to the original scope of the HERA programme are made, and cross references to topics also covered by other participants of the workshop are given. This includes topics on QCD, proton structure, diffraction, jets, hadronic final states, heavy flavours, electroweak physics, and the application of related theory and phenomenology topics like NNLO QCD calculations, low-x related models, nonperturbative QCD aspects, and electroweak radiative corrections. Synergies with other collider programmes are also addressed. In summary, the range of physics topics which can still be uniquely covered using the existing data is very broad and of considerable physics interest, often matching the interest of results from colliders currently in operation. Due to well-e...

  9. Possibilities with OHWC. Development and application of ECP-simulation in Swedish BWRs; Moejligheter med OHWC. Utveckling och tillaempning av ECP-simulering i svenska BWR

    Energy Technology Data Exchange (ETDEWEB)

    Lundgren, K. [ALARA Engineering, Skultuna (Sweden); Wikmark, G. [Advanced Nuclear Technology, Uppsala (Sweden)

    2000-02-01

    not possible to perform in all locations in the primary circuit. The combination well bench-marked measurements and computer model is therefore a prerequisite for optimisation of the HWC operation in a plant. In the text, the impact of Optimised HWC on cracking of austenitic materials is discussed. It is estimated that even lowering the potential by only 100 mV will reduce the crack growth rate by almost three times. A reduction by 200 mV could reduce the crack growth rate by eight times and 300 mV more than 20 times. The estimations are preliminary but indicate the potential efficiency of OHWC application. The calculations also show that both 'full' HWC operation and OHWC operation will lead to very different levels of the reducing conditions for various parts of the BWR systems. A more uniform, but high, level will be obtained by normal water chemistry. Finally, a number of areas where the current model can be applied or improved are presented.(abstract truncated)

  10. Application of the MST clustering to the high energy gamma-ray sky. IV - Blazar candidates found as possible counterparts of photon clusters

    CERN Document Server

    Campana, R; Bernieri, E

    2016-01-01

    We present the results of a cluster search in the Fermi-LAT Pass 8 gamma-ray sky by means of the Minimum Spanning Tree algorithm, at energies higher than 10 GeV and at Galactic latitudes higher than 25 degrees. The selected clusters have a minimum number of photons higher than or equal to 5, a high degree of concentration, and are without a clear corresponding counterpart in blazar catalogues. A sample of 30 possible gamma-ray sources was obtained. These objects were verified by applying the standard Maximum Likelihood analysis on the Fermi-LAT data. A search for possible radio counterparts in a circle having a radius of 6 arcmin was performed, finding several interesting objects, the majority of them without optical spectroscopical data. These can be considered as new blazar candidates. Some of them were already noticed as possible blazars or Active Galactic Nuclei in previous surveys, but never associated with high energy emission. These possible counterparts are reported and their properties are discussed.

  11. Possible future HERA analyses

    Energy Technology Data Exchange (ETDEWEB)

    Geiser, Achim

    2015-12-15

    A variety of possible future analyses of HERA data in the context of the HERA data preservation programme is collected, motivated, and commented. The focus is placed on possible future analyses of the existing ep collider data and their physics scope. Comparisons to the original scope of the HERA pro- gramme are made, and cross references to topics also covered by other participants of the workshop are given. This includes topics on QCD, proton structure, diffraction, jets, hadronic final states, heavy flavours, electroweak physics, and the application of related theory and phenomenology topics like NNLO QCD calculations, low-x related models, nonperturbative QCD aspects, and electroweak radiative corrections. Synergies with other collider programmes are also addressed. In summary, the range of physics topics which can still be uniquely covered using the existing data is very broad and of considerable physics interest, often matching the interest of results from colliders currently in operation. Due to well-established data and MC sets, calibrations, and analysis procedures the manpower and expertise needed for a particular analysis is often very much smaller than that needed for an ongoing experiment. Since centrally funded manpower to carry out such analyses is not available any longer, this contribution not only targets experienced self-funded experimentalists, but also theorists and master-level students who might wish to carry out such an analysis.

  12. The Department of Defense Superconductivity Research and Development (DSRD) Options. A Study of Possible Directions for Exploitation of Superconductivity in Military Applications.

    Science.gov (United States)

    1987-07-01

    refrigeration systems. In one very elegant example, DoD funded development of a miniature refrigerator, for which the heat exchanger, expansion orifice...specific heat and magnetization, both as functions of temperature and magnetic field. Such investigations provide measures of superconducting state...small-scale (sensors and electronics) applications. 29 13 Thermnal and magnetocaloric effects. All sources of thermal input to both small-scale and large

  13. Les réacteurs à membranes : possibilités d'application dans l'industrie pétrolière et pétrochimique Membrane Reactors: Possibilities of Application in the Petroleum and Petrochemical Industry

    Directory of Open Access Journals (Sweden)

    Guy C.

    2006-11-01

    Full Text Available Cet article fait le point sur l'état de la recherche dans le domaine des réacteurs chimiques avec séparation par membrane intégrée et de leur applications dans le domaine du raffinage et de la pétrochimie. Trois applications potentiellement intéressantes sont identifiées et, pour chacune, les avantages de l'utilisation d'un réacteur à membrane sont discutés. Ce sont : la déshydrogénation du propane en propylène, la déshydrogénation d'un naphtène cyclohexanique et le vaporéformage du gaz naturel. Pour ces réactions, les membranes à base de palladium apparaissent les plus performantes compte tenu de leur tenue en température, de leur sélectivité et de leur perméabilité à l'hydrogène. Quelques éléments relatifs à leur développement sont présentés en conclusion. Recently, the use of membrane in reaction engineering has been more and more advocated. The selective separation of the products from the reaction mixture allows to achieve higher conversion or better selectivity or to operate under less severe conditions or with smaller units. This paper presents an update on the recent advances in the field of chemical membrane reactors and on their applications in refining and petrochemistry. Previous work. Most of the possible applications of membrane reactors in petroleum and petrochemical industry concern gaseous catalytic reactions. For this reason, gas permeation membranes are the primary component of membrane reactors. Gas permeation membranes present different types of physical structure : dense, microporous or asymmetric which is a combination of the two. Separating properties of dense membranes are function of the solubility and diffusivity of each gaseous component in the membrane material. For microporous membranes, they follow four mechanisms : Knudsen diffusion, surface diffusion, capillary condensation or molecular sieving. Although organic polymers are the common constituent of gas permeation membrane, their

  14. Possibility of Application of RFID in the Express Delivery Company%试论 RFID 在快递公司应用的可能性

    Institute of Scientific and Technical Information of China (English)

    梁雁

    2015-01-01

    探讨电子商务环境下快递业的发展及瓶颈,提出基于 RFID 技术的解决方案,论述其运用的可能性、问题与对策,可供相关物流企业参考。%To explore the development and bottleneck of express industry under the environment of e -commerce,puts forward a solution based on RFID technology,discusses the problems and countermeasures,the possibility of using,which can be a reference for the related logistics enterprise.

  15. Application of electrolysis for inactivation of an antiviral drug that is one of possible selection pressure to drug-resistant influenza viruses.

    Science.gov (United States)

    Kobayashi, Toyohide; Hirose, Jun; Wu, Hong; Sano, Kouichi; Katsumata, Takahiro; Tsujibo, Hiroshi; Nakano, Takashi

    2013-12-01

    The recent development of antiviral drugs has led to concern that the release of the chemicals in surface water due to expanded medical use could induce drug-resistant mutant viruses in zoonosis. Many researchers have noted that the appearance of an oseltamivir (Tamiflu(®))-resistant avian influenza mutant virus, which may spread to humans, could be induced by oseltamivir contamination of surface water. Although past studies have reported electrolysis as a possible method for degradation of antineoplastics and antibacterials in water, the validity of the method for treatment of antiviral drugs is unknown. In this study, electrolysis was used to degrade an antiviral prodrug, oseltamivir, and a stable active form, oseltamivir carboxylate, and the degradation process was monitored with HPLC-UV and the neuraminidase inhibitory assay. HPLC-UV-detectable oseltamivir and oseltamivir carboxylate were decomposed by electrolysis within 60 min, and inhibitory activity of neuraminidase decreased below the detection limit of the assay used. Cytotoxic and genotoxic activity were not detected in electrolyzed fluid. These results indicate that electrolysis is a possible treatment for inactivation of the antiviral drug oseltamivir.

  16. Biological activities of ribosome-inactivating proteins and their possible applications as antimicrobial, anticancer, and anti-pest agents and in neuroscience research.

    Science.gov (United States)

    Akkouh, Ouafae; Ng, Tzi Bun; Cheung, Randy Chi Fai; Wong, Jack Ho; Pan, Wenliang; Ng, Charlene Cheuk Wing; Sha, Ou; Shaw, Pang Chui; Chan, Wai Yee

    2015-12-01

    Ribosome-inactivating proteins (RIPs) are enzymes which depurinate ribosomal RNA (rRNA), thus impeding the process of translation resulting in inhibition of protein synthesis. They are produced by various organisms including plants, fungi and bacteria. RIPs from plants are linked to plant defense due to their antiviral, antifungal, antibacterial, and insecticidal activities in which they can be applied in agriculture to combat microbial pathogens and pests. Their anticancer, antiviral, embryotoxic, and abortifacient properties may find medicinal applications. Besides, conjugation of RIPs with antibodies or other carriers to form immunotoxins has been found useful to research in neuroscience and anticancer therapy.

  17. Possible biomedical applications and limitations of a variable-force centrifuge on the lunar surface: A research tool and an enabling resource

    Science.gov (United States)

    Cowing, Keith L.

    1992-01-01

    Centrifuges will continue to serve as a valuable research tool in gaining an understanding of the biological significance of the inertial acceleration due to gravity. Space- and possibly lunar-based centrifuges will play a significant and enabling role with regard to the human component of future lunar and martian exploration, both as a means of accessing potential health and performance risks and as a means of alleviating these risks. Lunar-based centrifuges could be particularly useful as part of a program of physiologic countermeasures designed to alleviate the physical deconditioning that may result from prolonged exposure to a 1/6-g environment. Centrifuges on the lunar surface could also be used as part of a high-fidelity simulation of a trip to Mars. Other uses could include crew readaptation to 1 g, waste separation, materials processing, optical mirror production in situ on the Moon, and laboratory specimen separation.

  18. On the possibility to discriminate the mass of the primary cosmic ray using the muon arrival times from extensive air showers: Application for Pierre Auger Observatory

    Energy Technology Data Exchange (ETDEWEB)

    Arsene, N.; Rebel, H.; Sima, O. [Institute of Space Science (ISS), Bucharest-Magurele, P.O. Box MG-23 (Romania) and Physics Department, University of Bucharest, Bucharest-Magurele (Romania); Karlsruhe Institute of Technology, Karlsruhe (Germany); Physics Department, University of Bucharest, Bucharest-Magurele (Romania)

    2012-11-20

    In this paper we study the possibility to discriminate the mass of the primary cosmic ray by observing the muon arrival times in ground detectors. We analyzed extensive air showers (EAS) induced by proton and iron nuclei with the same energy 8 Multiplication-Sign 10{sup 17} eV simulated with CORSIKA, and analyzed the muon arrival times at ground measured by the infill array detectors of the Pierre Auger Observatory (PAO). From the arrival times of the core and of the muons the atmospheric depth of muon generation locus is evaluated. The results suggest a potential mass discrimination on the basis of muon arrival times and of the reconstructed atmospheric depth of muon production. An analysis of a larger set of CORSIKA simulations carried out for primary energies above 10{sup 18} eV is in progress.

  19. A structural approach to control of transitional waves of nonlinear diffusion-reaction systems: Theory and possible applications to bio-medicine

    Directory of Open Access Journals (Sweden)

    Victor Kardashov

    2002-01-01

    Full Text Available This paper has considered a novel approach to structural recognition and control of nonlinear reaction-diffusion systems (systems with density dependent diffusion. The main consistence of the approach is interactive variation of the nonlinear diffusion and sources structural parameters that allows to implement a qualitative control and recognition of transitional system conditions (transients. The method of inverse solutions construction allows formulating the new analytic conditions of compactness and periodicity of the transients that is also available for nonintegrated systems. On the other hand, using of energy conservations laws, allows transfer to nonlinear dynamics models that gives the possiblity to apply the modern deterministic chaos theory (particularly the Feigenboum's universal constants and scenario of chaotic transitions.

  20. Cue-induced Behavioral and Neural Changes among Excessive Internet Gamers and Possible Application of Cue Exposure Therapy to Internet Gaming Disorder

    Science.gov (United States)

    Zhang, Yongjun; Ndasauka, Yamikani; Hou, Juan; Chen, Jiawen; Yang, Li zhuang; Wang, Ying; Han, Long; Bu, Junjie; Zhang, Peng; Zhou, Yifeng; Zhang, Xiaochu

    2016-01-01

    Internet gaming disorder (IGD) may lead to many negative consequences in everyday life, yet there is currently no effective treatment for IGD. Cue-reactivity paradigm is commonly used to evaluate craving for substance, food, and gambling; cue exposure therapy (CET) is applied to treating substance use disorders (SUDs) and some other psychological disorders such as pathological gambling (PG). However, no study has explored CET’s application to the treatment of IGD except two articles having implied that cues’ exposure may have therapeutic effect on IGD. This paper reviews studies on cue-induced behavioral and neural changes in excessive Internet gamers, indicating that behavioral and neural mechanisms of IGD mostly overlap with those of SUD. The CET’s effects in the treatment of SUDs and PG are also reviewed. We finally propose an optimized CET paradigm, which future studies should consider and investigate as a probable treatment of IGD. PMID:27242589

  1. Laser Nanosoldering of Golden and Magnetite Particles and its Possible Application in 3D Printing Devices and Four-Valued Non-Volatile Memories

    Directory of Open Access Journals (Sweden)

    Jaworski Jacek

    2015-12-01

    Full Text Available In recent years the 3D printing methods have been developing rapidly. This article presents researches about a new composite consisted of golden and magnetite nanoparticles which could be used for this technique. Preparation of golden nanoparticles by laser ablation and their soldering by laser green light irradiation proceeded in water environment. Magnetite was obtained on chemical way. During experiments it was tested a change of a size of nanoparticles during laser irradiation, surface plasmon resonance, zeta potential. The obtained golden - magnetite composite material was magnetic after laser irradiation. On the end there was considered the application it for 3D printing devices, water filters and four-valued non-volatile memories.

  2. Characterization of the axial plasma shock in a table top plasma focus after the pinch and its possible application to testing materials for fusion reactors

    Energy Technology Data Exchange (ETDEWEB)

    Soto, Leopoldo, E-mail: lsoto@cchen.cl; Pavez, Cristian; Moreno, José [Comisión Chilena de Energía Nuclear, Casilla 188-D, Santiago (Chile); Centro de Investigación y Aplicaciones en Física de Plasmas y Potencia Pulsada, P" 4, Santiago-Talca (Chile); Departamento de Ciencias Físicas, Facultad de Ciencias Exactas, Universidad Andrés Bello, República 220, Santiago (Chile); Inestrosa-Izurieta, María José [Comisión Chilena de Energía Nuclear, Casilla 188-D, Santiago (Chile); Centro de Investigación y Aplicaciones en Física de Plasmas y Potencia Pulsada, P" 4, Santiago-Talca (Chile); Veloso, Felipe [Instituto de Física, Pontificia Universidad Católica de Chile, Santiago (Chile); Gutiérrez, Gonzalo [Departamento de Física, Facultad de Ciencias, Universidad de Chile, Santiago (Chile); Vergara, Julio [Facultad de Ingeniería, Pontificia Universidad Católica de Chile, Santiago (Chile); Clausse, Alejandro [CNEA-CONICET and Universidad Nacional del Centro, 7000 Tandil (Argentina); Bruzzone, Horacio [CONICET and Universidad de Mar del Plata, Mar del Plata (Argentina); Castillo, Fermín [Instituto de Ciencias Físicas, Universidad Nacional Autónoma de México, Cuernavaca, Morelos (Mexico); and others

    2014-12-15

    The characterization of plasma bursts produced after the pinch phase in a plasma focus of hundreds of joules, using pulsed optical refractive techniques, is presented. A pulsed Nd-YAG laser at 532 nm and 8 ns FWHM pulse duration was used to obtain Schlieren images at different times of the plasma dynamics. The energy, interaction time with a target, and power flux of the plasma burst were assessed, providing useful information for the application of plasma focus devices for studying the effects of fusion-relevant pulses on material targets. In particular, it was found that damage factors on targets of the order of 10{sup 4} (W/cm{sup 2})s{sup 1/2} can be obtained with a small plasma focus operating at hundred joules.

  3. Cue-induced Behavioral and Neural Changes among Excessive Internet Gamers and Possible Application of Cue Exposure Therapy to Internet Gaming Disorder

    Directory of Open Access Journals (Sweden)

    Yongjun eZhang

    2016-05-01

    Full Text Available Internet gaming disorder (IGD may lead to many negative consequences in everyday life, yet there is currently no effective treatment for IGD. Cue-reactivity paradigm is commonly used to evaluate craving for substance, food, and gambling; cue exposure therapy (CET is applied to treating substance use disorders (SUDs and some other psychological disorders such as pathological gambling (PG. However, no study has explored CET’s application to the treatment of IGD except two articles having implied that cues’ exposure may have therapeutic effect on IGD. This paper reviews studies on cue-induced behavioral and neural changes in excessive Internet gamers, indicating that behavioral and neural mechanisms of IGD mostly overlap with those of SUD. The CET’s effects in the treatment of SUDs and PG are also reviewed. We finally propose an optimized CET paradigm, which future studies should consider and investigate as a probable treatment of IGD.

  4. Cue-induced Behavioral and Neural Changes among Excessive Internet Gamers and Possible Application of Cue Exposure Therapy to Internet Gaming Disorder.

    Science.gov (United States)

    Zhang, Yongjun; Ndasauka, Yamikani; Hou, Juan; Chen, Jiawen; Yang, Li Zhuang; Wang, Ying; Han, Long; Bu, Junjie; Zhang, Peng; Zhou, Yifeng; Zhang, Xiaochu

    2016-01-01

    Internet gaming disorder (IGD) may lead to many negative consequences in everyday life, yet there is currently no effective treatment for IGD. Cue-reactivity paradigm is commonly used to evaluate craving for substance, food, and gambling; cue exposure therapy (CET) is applied to treating substance use disorders (SUDs) and some other psychological disorders such as pathological gambling (PG). However, no study has explored CET's application to the treatment of IGD except two articles having implied that cues' exposure may have therapeutic effect on IGD. This paper reviews studies on cue-induced behavioral and neural changes in excessive Internet gamers, indicating that behavioral and neural mechanisms of IGD mostly overlap with those of SUD. The CET's effects in the treatment of SUDs and PG are also reviewed. We finally propose an optimized CET paradigm, which future studies should consider and investigate as a probable treatment of IGD.

  5. Novel lead-graphene and lead-graphite metallic composite materials for possible applications as positive electrode grid in lead-acid battery

    Science.gov (United States)

    Yolshina, L. A.; Yolshina, V. A.; Yolshin, A. N.; Plaksin, S. V.

    2015-03-01

    Novel lead-graphene and lead-graphite metallic composites which melt at temperature of the melting point of lead were investigated as possible positive current collectors for lead acid batteries in sulfuric acid solution. Scanning electron microscopy, Raman spectroscopy, difference scanning calorimetry, cyclic voltammetry and prolonged corrosion tests were employed to characterize the effect of the newly proposed lead-carbon metallic composites on the structure and electrochemical properties of positive grid material. Both lead-graphene and lead-graphite metallic composite materials show the similar electrochemical characteristics to metallic lead in the voltage range where the positive electrodes of lead acid batteries operate. It has been shown that carbon both as graphene and graphite does not participate in the electrochemical process but improve corrosion and electrochemical characteristics of both metallic composite materials. No products of interaction of lead with sulfuric acid were formed on the surface of graphene and graphite so as it was not found additional peaks of carbon discharge on voltammograms which could be attributed to the carbon. Graphene inclusions in lead prevent formation of leady oxide nanocrystals which deteriorate discharge characteristics of positive electrode of LAB. Both lead-graphene alloy and lead-graphite metallic composite proved excellent electrochemical and corrosion behavior and can be used as positive grids in lead acid batteries of new generation.

  6. Warm gas phase chemistry as possible origin of high HDO/H2O ratios in hot and dense gases: application to inner protoplanetary discs

    CERN Document Server

    Thi, Wing-Fai; Kamp, Inga

    2009-01-01

    The origin of Earth oceans is controversial. Earth could have acquired its water either from hydrated silicates (wet Earth scenario) or from comets (dry Earth scenario). [HDO]/[H2O] ratios are used to discriminate between the scenarios. High [HDO]/[H2O] ratios are found in Earth oceans. These high ratios are often attributed to the release of deuterium enriched cometary water ice, which was formed at low gas and dust temperatures. Observations do not show high [HDO]/[H2O] in interstellar ices. We investigate the possible formation of high [HDO]/[H2O] ratios in dense (nH> 1E6 cm^{-3}) and warm gas (T=100-1000 K) by gas-phase photochemistry in the absence of grain surface chemistry. We derive analytical solutions, taking into account the major neutral-neutral reactions for gases at T>100 K. The chemical network is dominated by photodissociation and neutral-neutral reactions. Despite the high gas temperature, deuterium fractionation occurs because of the difference in activation energy between deuteration enrich...

  7. Investigation of Laser Induced Breakdown Spectroscopy (LIBS) for the Differentiation of Nerve and Gland Tissue—A Possible Application for a Laser Surgery Feedback Control Mechanism

    Science.gov (United States)

    Mehari, F.; Rohde, M.; Knipfer, C.; Kanawade, R.; Klämpfl, F.; W., Adler; Oetter, N.; Stelzle, F.; Schmidt, M.

    2016-06-01

    Laser surgery provides clean, fast and accurate modeling of tissue. However, the inability to determine what kind of tissue is being ablated at the bottom of the cut may lead to the iatrogenic damage of structures that were meant to be preserved. In this context, nerve preservation is one of the key challenges in any surgical procedure. One example is the treatment of parotid gland pathologies, where the facial nerve (N. VII) and its main branches run through and fan out inside the glands parenchyma. A feedback system that automatically stops the ablation to prevent nerve-tissue damage could greatly increase the applicability and safety of surgical laser systems. In the present study, Laser Induced Breakdown Spectroscopy (LIBS) is used to differentiate between nerve and gland tissue of an ex-vivo pig animal model. The LIBS results obtained in this preliminary experiment suggest that the measured spectra, containing atomic and molecular emissions, can be used to differentiate between the two tissue types. The measurements and differentiation were performed in open air and under normal stray light conditions.

  8. Determination of application possibilities of microwave heating in the curing process of water glass molding sands with fluid esters. Part 1

    Directory of Open Access Journals (Sweden)

    K. Granat

    2009-01-01

    Full Text Available This article presents results of the experimental trial of combination of the chemical method of water glass molding sands’ curing, used in foundry industry, with an innovative microwave heating. The research objective was to indicate at new areas of microwave energy application. The sands prepared, according to recommendations for curing technology, with the use of ethylene glycol diacetate, have been subject to microwave influence. The attempt at determination of microwave influence on qualitative changes of the binding bridges created during the curing process concerned such parameters as: bending and tensile strength, permeability as well as wear resistance. Moreover,we also determined the influence of microwave curing on the phenomena accompanying the process as well as bond stability (storage time of the prepared molding and core sands. It has been found, basing on the result analysis, that the innovative microwave heating might constitute a very good supplementation of the ester curing method. The advantages of the combined chemical and microwave gelation process include, among others, improvement of the described resistance and technological parameters as well as significant decrease of preparation time of foundry moulds and cores. The subject discussed in this article will be continued in its second part.

  9. The Pelletron Accelerator of IFUNAM and its possible applications to the dosimetry; El Acelerador Pelletron del IFUNAM y sus posibles aplicaciones a la dosimetria

    Energy Technology Data Exchange (ETDEWEB)

    Rickards, J. [Instituto de Fisica, UNAM, Circuito Exterior, C.U. 04510 Mexico D.F. (Mexico)

    1999-07-01

    The Pelletron Accelerator of positive ions 3 MV in the Institute of Physics of UNAM has characteristics that make it useful for the application to the radiations dosimetry. It is ideal for studying the detailed mechanisms of the radiation interaction with matter, therefore it can be applied to know the performance of dosemeters. With this device can be accelerated almost any type of ion, including He, but excepting the others noble gases. The energies of the disposable ions are in the interval 1 MeV until several MeV, depending of the state of charge selected, the energy can be varied continuously with accuracy of some KeV. It can be achieved streams from 10{sup 4} until 10{sup 6} ions/cm{sup 2}, allowing studies of individual events (tracks) or of collective processes. the beam size can be varying from a diameter 1 mm until 5 cm. It is also took in account with detectors and other techniques associated that can be combined for supporting studies, as surface barrier detectors and of other types, as well as the RBS, PIXE, RN techniques and channeling. (Author)

  10. Application of MODIS Products to Infer Possible Relationships Between Basin Land Cover and Coastal Waters Turbidity Using the Magdalena River, Colombia, as a Case Study

    Science.gov (United States)

    Madrinan, Max Jacobo Moreno; Cordova, Africa Flores; Olivares, Francisco Delgado; Irwin, Dan

    2012-01-01

    Basin development and consequent change in basin land cover have been often associated with an increased turbidity in coastal waters because of sediment yield and nutrients loading. The later leads to phytoplankton abundance further exacerbating water turbidity. This subsequently affects biological and physical processes in coastal estuaries by interfering with sun light penetration to coral reefs and sea grass, and even affecting public health. Therefore, consistent estimation of land cover changes and turbidity trend lines is crucial to design environmental and restoration management plans, to predict fate of possible pollutants, and to estimate sedimentary fluxes into the ocean. Ground solely methods to estimate land cover change would be unpractical and traditional methods of monitoring in situ water turbidity can be very expensive and time consuming. Accurate monitoring on the status and trends of basin land cover as well as the water quality of the receiving water bodies are required for analysis of relationships between the two variables. Use of remote sensing (RS) technology provides a great benefit for both fields of study, facilitating monitoring of changes in a timely and cost effective manner and covering wide areas with long term measurements. In this study, the Magdalena River basin and fixed geographical locations in the estuarine waters of its delta are used as a case to study the temporal trend lines of both, land cover change and the reflectance of the water turbidity using satellite technology. Land cover data from a combined product between sensors Terra and Aqua (MCD12Q1) from MODIS will be adapted to the conditions in the Magdalena basin to estimate changes in land cover since year 2000 to 2009. Surface reflectance data from a MODIS, Terra (MOD09GQ), band 1, will be used in lieu of in situ water turbidity for the time period between 2000 and present. Results will be compared with available existing data.

  11. Persistent Possible Science Selves

    Science.gov (United States)

    Mills, Leila A.; Lin, Lin

    2014-01-01

    This paper examines literature on the development of self-knowledge for possible selves--how an individual thinks about oneself and one's potential future selves (Markus & Nurius, 1986). Future science selves research, a recent offshoot of possible selves theories, centers on the development and loss of future possible scientific selves and…

  12. Sulfated polysaccharide, curdlan sulfate, efficiently prevents entry/fusion and restricts antibody-dependent enhancement of dengue virus infection in vitro: a possible candidate for clinical application.

    Science.gov (United States)

    Ichiyama, Koji; Gopala Reddy, Sindhoora Bhargavi; Zhang, Li Feng; Chin, Wei Xin; Muschin, Tegshi; Heinig, Lars; Suzuki, Youichi; Nanjundappa, Haraprasad; Yoshinaka, Yoshiyuki; Ryo, Akihide; Nomura, Nobuo; Ooi, Eng Eong; Vasudevan, Subhash G; Yoshida, Takashi; Yamamoto, Naoki

    2013-01-01

    Curdlan sulfate (CRDS), a sulfated 1→3-β-D glucan, previously shown to be a potent HIV entry inhibitor, is characterized in this study as a potent inhibitor of the Dengue virus (DENV). CRDS was identified by in silico blind docking studies to exhibit binding potential to the envelope (E) protein of the DENV. CRDS was shown to inhibit the DENV replication very efficiently in different cells in vitro. Minimal effective concentration of CRDS was as low as 0.1 µg/mL in LLC-MK2 cells, and toxicity was observed only at concentrations over 10 mg/mL. CRDS can also inhibit DENV-1, 3, and 4 efficiently. CRDS did not inhibit the replication of DENV subgenomic replicon. Time of addition experiments demonstrated that the compound not only inhibited viral infection at the host cell binding step, but also at an early post-attachment step of entry (membrane fusion). The direct binding of CRDS to DENV was suggested by an evident reduction in the viral titers after interaction of the virus with CRDS following an ultrafiltration device separation, as well as after virus adsorption to an alkyl CRDS-coated membrane filter. The electron microscopic features also showed that CRDS interacted directly with the viral envelope, and caused changes to the viral surface. CRDS also potently inhibited DENV infection in DC-SIGN expressing cells as well as the antibody-dependent enhancement of DENV-2 infection. Based on these data, a probable binding model of CRDS to DENV E protein was constructed by a flexible receptor and ligand docking study. The binding site of CRDS was predicted to be at the interface between domains II and III of E protein dimer, which is unique to this compound, and is apparently different from the β-OG binding site. Since CRDS has already been tested in humans without serious side effects, its clinical application can be considered.

  13. Sulfated polysaccharide, curdlan sulfate, efficiently prevents entry/fusion and restricts antibody-dependent enhancement of dengue virus infection in vitro: a possible candidate for clinical application.

    Directory of Open Access Journals (Sweden)

    Koji Ichiyama

    Full Text Available Curdlan sulfate (CRDS, a sulfated 1→3-β-D glucan, previously shown to be a potent HIV entry inhibitor, is characterized in this study as a potent inhibitor of the Dengue virus (DENV. CRDS was identified by in silico blind docking studies to exhibit binding potential to the envelope (E protein of the DENV. CRDS was shown to inhibit the DENV replication very efficiently in different cells in vitro. Minimal effective concentration of CRDS was as low as 0.1 µg/mL in LLC-MK2 cells, and toxicity was observed only at concentrations over 10 mg/mL. CRDS can also inhibit DENV-1, 3, and 4 efficiently. CRDS did not inhibit the replication of DENV subgenomic replicon. Time of addition experiments demonstrated that the compound not only inhibited viral infection at the host cell binding step, but also at an early post-attachment step of entry (membrane fusion. The direct binding of CRDS to DENV was suggested by an evident reduction in the viral titers after interaction of the virus with CRDS following an ultrafiltration device separation, as well as after virus adsorption to an alkyl CRDS-coated membrane filter. The electron microscopic features also showed that CRDS interacted directly with the viral envelope, and caused changes to the viral surface. CRDS also potently inhibited DENV infection in DC-SIGN expressing cells as well as the antibody-dependent enhancement of DENV-2 infection. Based on these data, a probable binding model of CRDS to DENV E protein was constructed by a flexible receptor and ligand docking study. The binding site of CRDS was predicted to be at the interface between domains II and III of E protein dimer, which is unique to this compound, and is apparently different from the β-OG binding site. Since CRDS has already been tested in humans without serious side effects, its clinical application can be considered.

  14. [Amaranth flour: characteristics, comparative analysis, application possibilities].

    Science.gov (United States)

    Zharkov, I M; Miroshnichenko, L A; Zviagin, A A; Bavykina, I A

    2014-01-01

    Amaranth flour--a product of amaranth seeds processing--is a valuable industrial raw material that has an unique chemical composition and may be used for nutrition of people suffering from intolerance to traditional cereals protein, including celiac disease patients. The research aim was to study the composition of amaranth flour of two types compared with semolina which is traditionally used for nutrition by Russian population, as well as to compare the composition of milk amaranth flour porridge with milk semolina porridge. The composition of amaranth whole-ground flour and amaranth flour of premium grade processed from amaranth seeds grown in Voronezh region has been researched. It is to be noted that protein content in amaranth flour was 10.8-24.3% higher than in semolina, and its biological value and NPU-coefficient were higher by 22.65 and 46.51% respectively; lysine score in amaranth flour protein of premium grade came up to 107.54%, and in semolina protein only 40.95%. The level of digestible carbohydrates, including starch, was lower in amaranth flour than in semolina by 2.79-12.85 and 4.76-15.85% respectively, while fiber content was 15.5-30 fold higher. Fat content in amaranth flour of premium grade was 2,4 fold lower than in whole-ground amaranth flour but it was 45% higher than in semolina. The main advantage of amaranth flour protein compared to wheat protein is the predominance of albumins and globulins and a minimal content of prolamines and alpha-gliadin complete absence. The specifics of chemical composition allow the amaranth flour to be recommended for being included into nutrition of both healthy children and adults and also celiac disease patients.

  15. Activity based costing for regulated services. Experiences, fundamental guidance and possible application to network activity in the electric power sector; Aktivitetsbasert kalkulasjon for regulerte tjenester. Erfaringer, prinsipielle retningslinjer og mulig anvendelse for nettvirksomhet i kraftsektoren

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerndal, Mette; Bjoernenak, Trond; Johnsen, Thore

    2003-07-01

    This report discusses the application of norm cost models to income regulation of distribution networks in the electric power sector. It deals in particular with the possibility of using activity based costing (ABC), but also discusses more general use of structural cost models in income regulation. The report presents experiences with the ABC method in various regulated service industries. For income regulation in the network activities, the relevance of ABC based systems is primarily related to activities conducted by the number of customers. Analyses of costs in the sector show large variations in these costs, which may indicate a potential for this type of regulation model. Finally the report discusses the handling of capital costs in the regulation model, which is important for any regulation regime.

  16. 浅述气压盘式制动器在城市客车上应用的可能性与可行性%Possibility and feasibility of air pressure disc brake applicated in city bus

    Institute of Scientific and Technical Information of China (English)

    孙吉宝; 温述波

    2012-01-01

    Analyse the possiblity and feasibility of air pressure disc brake applicated in city bus,focus on discussing the development of 5.5t disc brake front axle,and calculate the brake moment of disc brake front axle and drum brake front axle.%分析了气压盘式制动器在城市客车上应用的可能性与可行性,重点论述了5.5T盘式制动器前桥的开发,并对盘式制动器前桥与鼓式制动器前桥的制动力矩进行对比计算。

  17. [The diagnostic possibilities of saliva].

    Science.gov (United States)

    Kochurova, E V; Kozlov, S V

    2014-01-01

    Saliva is a clinically informative biological fluid which contains multitude of bio-markers. This characteristic makes it possible to carry out numerous analyzes for developing mode to test patient in situ, express-tests included. The diagnostic by saliva is a new area of more simple application both markers and analyzers that can be useful in diagnostic of diseases of oral cavity, oncological diseases included. The using of saliva expands perspectives for making clinical diagnosis and establishment of dynamics and monitoring of disease.

  18. Another Theory is Possible

    DEFF Research Database (Denmark)

    Manners, Ian James

    2016-01-01

    that seek to actively challenge the mainstream of the study of Europe. The article briefly examines the discipline of mainstreaming, then surveys the extent of polyphonic engagement in EU studies, before setting out how the special issue contributors move beyond the mainstream. The article will argue...... theory, is possible – indeed, probable....

  19. IS DISCONTINUOUS BERGSONISM POSSIBLE?

    Directory of Open Access Journals (Sweden)

    TERESA CASTELÃO-LAWLESS

    2010-11-01

    Full Text Available Gaston Bachelard’s position toward the philosophy of Henri Bergson is most interesting. In La Dialectique de la durée (1936, Bachelard claims that “of Bergsonism we accept everything but continuity” and that the rest of his book will be an attempt to show the possibility of a “discontinuous Bergsonism”. In this paper, I focus on the reaction of Bachelard to works of Bergson such as the Essai sur les données immédiates de la conscience (1889, L’Evolution créatrice (1907, and Durée et simultanéité: à propos de la théorie d’Einstein (1922 and demonstrate that even though the conditions necessary for the possibility of a discontinuous Bergsonism are not the same ones which Bachelard had in mind when he accepted most of Bergsonism, their phenomenologies of the scientific spirit were analogous.

  20. Possible number systems.

    Science.gov (United States)

    Rips, Lance J; Thompson, Samantha

    2014-03-01

    Number systems-such as the natural numbers, integers, rationals, reals, or complex numbers-play a foundational role in mathematics, but these systems can present difficulties for students. In the studies reported here, we probed the boundaries of people's concept of a number system by asking them whether "number lines" of varying shapes qualify as possible number systems. In Experiment 1, participants rated each of a set of number lines as a possible number system, where the number lines differed in their structures (a single straight line, a step-shaped line, a double line, or two branching structures) and in their boundedness (unbounded, bounded below, bounded above, bounded above and below, or circular). Participants also rated each of a group of mathematical properties (e.g., associativity) for its importance to number systems. Relational properties, such as associativity, predicted whether participants believed that particular forms were number systems, as did the forms' ability to support arithmetic operations, such as addition. In Experiment 2, we asked participants to produce properties that were important for number systems. Relational, operation, and use-based properties from this set again predicted ratings of whether the number lines were possible number systems. In Experiment 3, we found similar results when the number lines indicated the positions of the individual numbers. The results suggest that people believe that number systems should be well-behaved with respect to basic arithmetic operations, and that they reject systems for which these operations produce ambiguous answers. People care much less about whether the systems have particular numbers (e.g., 0) or sets of numbers (e.g., the positives).

  1. A Garden of Possibilities

    CERN Multimedia

    Carolyn Lee

    2010-01-01

    Renowned landscape architect and designer Charles Jencks recently visited CERN along with the architect of the Globe, Hervé Dessimoz, to investigate the possibility of creating a cosmic-inspired garden at the entrance to the Laboratory.   Left to right: Charles Jencks, Peter Higgs, Rolf Heuer in the garden of cosmic speculation. Photo credit: University of Edinburgh/Maverick photo agency Charles Jencks is a master at designing whimsical, intriguing outdoor spaces that hold a much deeper meaning than just an interesting view. His Garden of Cosmic Speculation at his home in Scotland uses designs recalling cosmic forces, DNA, organic cells, spirals of time, black holes and the Universe, made with landform, plants, sculpture and water to re-shape the natural landscape. One of the possible symbols for CERN that came to his mind was the cosmic uroborus, an ancient Egyptian symbol of a snake eating its own tail dating back to 1600 BC. “Many scientists have discussed this as a poss...

  2. High-dose-rate brachytherapy with local injection of bleomycin for N0 oral tongue cancer. Possibilities of the control of tumor implant by inserting applicators and the decrease in tumor dose

    Energy Technology Data Exchange (ETDEWEB)

    Ohga, Saiji; Uehara, Satoru [National Kyushu Medical Center Hospital, Fukuoka (Japan); Miyoshi, Makoto [Kitakyushu Municipal Medical Center Hospital, Fukuoka (Japan); Jingu, Kenichi [Fukuoka Univ. (Japan). School of Medicine

    2003-01-01

    Twenty-eight patients with N0 oral tongue cancer were treated with high-dose-rate (HDR) interstitial brachytherapy combined with local injection of bleomycin between December 1997 and June 2001 at the Department of Radiology, National Kyushu Medical Center Hospital. A median dose of 5 mg of bleomycin was injected locally, and 16-20 Gy was delivered to the area surrounding applicators for control of the tumor implant during the initial two days. The two-year local recurrence-free survival rate was 96% [T1, 2: 100% (8/8, 15/15), T3: 80% (4/5)]. The two-year secondary neck node metastasis rate was 7.1% [T1: 12.5% (1/8), T2: 6.7% (1/15), T3: 0% (0/5)]. There were no tumor implants in any patients. We tried to decrease the minimal tumor dose step by step. The groups with median minimal tumor doses of 60 Gy, 50 Gy, and 40 Gy had local recurrence rates of 12.5% (1/8), 0% (0/14), and 0% (0/6), respectively. Local recurrence rates were not increased by decreasing the minimal tumor dose. Two patients (7%) had secondary neck node metastasis. Late adverse effects were tongue ulcer: 11% (3/28), oral floor ulcer: 4% (1/28), and osteonecrosis: 4% (1/28). These results suggest that control of the tumor implant and the decrease in minimal tumor dose below 60 Gy may be possible with the local injection of bleomycin and delivery of doses to the area surrounding the applicators when N0 tongue cancer is treated using {sup 192}Ir-HDR brachytherapy. (author)

  3. Increasing Possibilities of Nanosuspension

    Directory of Open Access Journals (Sweden)

    Kumar Bishwajit Sutradhar

    2013-01-01

    Full Text Available Nowadays, a very large proportion of new drug candidates emerging from drug discovery programmes are water insoluble and thus poorly bioavailable. To avoid this problem, nanotechnology for drug delivery has gained much interest as a way to improve the solubility problems. Nano refers to particles size range of 1–1000 nm. The reduction of drug particles into the submicron range leads to a significant increase in the dissolution rate and therefore enhances bioavailability. Nanosuspensions are part of nanotechnology. This interacts with the body at subcellular (i.e., molecular scales with a high degree of specificity and can be potentially translated into targeted cellular and tissue-specific clinical applications designed to achieve maximal therapeutic efficacy with minimal side effects. Production of drugs as nanosuspensions can be developed for drug delivery systems as an oral formulation and nonoral administration. Here, this review describes the methods of pharmaceutical nanosuspension production including advantages and disadvantages, potential benefits, characterization tests, and pharmaceutical applications in drug delivery.

  4. From Necessity to Possibility

    Directory of Open Access Journals (Sweden)

    Charles Cullum

    2015-12-01

    Full Text Available This article applies theories of fragmented postmodern identity and Heidegger’s modes of existence and concept of historicality to the issue of passing and traces the treatment of that motif across six African American novels that move from the largely realistic perspective of the 19th century to the subjectivist perspective of the early 20th century. These novels thus foreshadow the postmodernist questioning of the basis of discrete personal identity. The article claims that, across these novels, the act of passing and its relationship to human identity through time and historical circumstance becomes problematized from a necessary tool for escaping slavery, and so sustaining identity in its most basic form as life itself, to a potential existential dilemma of identity as a matter of authenticity and possibility. The article further discusses whether the individual is constrained by his or her background, especially, by race itself, or is a totally free, ungrounded agent.

  5. Synthesis and characterization of thin films of Pd/TiO{sub 2} with possible applications in photo catalysis; Sintesis y caracterizacion de peliculas delgadas de Pd/TiO{sub 2} con posibles aplicaciones en fotocatalisis

    Energy Technology Data Exchange (ETDEWEB)

    Tirado G, S. [IPN, Escuela Superior de Fisica y Matematicas, U. P. Adolfo Lopez Mateos Edif. 9, San Pedro Zacatenco, 07738 Mexico D. F. (Mexico); Valenzuela Z, M. A., E-mail: tirado@esfm.ipn.mx [IPN, Escuela Superior de Ingenieria Quimica e Industrias Extractivas, Laboratorio de Catalisis y Materiales, U. P. Adolfo Lopez Mateos Edif. 8, San Pedro Zacatenco, 07738 Mexico D. F. (Mexico)

    2015-10-15

    In this paper the synthesis and study of thin films of titanium oxide is reported, as well as those that were surface modified with palladium nanoparticles Pd/TiO{sub 2}. First, the TiO{sub 2} films are grown on substrates of soda-lime glass using chemical sol-gel route and the repeated immersion procedure. The salt precursor titanium oxy-acetylacetonate to 0.2 M, in the solvent 2-methoxyethanol and monoethanolamine was used as stabilizer. The number of used immersions gave an average thickness estimate for these films of 172.8 nm. Second, the series of Pd/TiO{sub 2} films surface modified were obtained from a solution of palladium nitrate dehydrate at low concentration, with the same procedure. The films grown TiO{sub 2} and those surface-modified films were characterized in its structure by X-ray diffraction, morphology by scanning electron microscopy, the topography with atomic force microscopy, optical properties by UV-Vis, among others. Photoluminescence properties and/or possible applications in photo catalysis are reported in this paper. (Author)

  6. Future possibilities in migraine genetics

    DEFF Research Database (Denmark)

    Rudkjøbing, Laura Aviaja; Esserlind, Ann-Louise; Olesen, Jes

    2012-01-01

    Migraine with and without aura (MA and MO, respectively) have a strong genetic basis. Different approaches using linkage-, candidate gene- and genome-wide association studies have been explored, yielding limited results. This may indicate that the genetic component in migraine is due to rare......, the technology will follow, rendering these approaches more applicable in the search for causative migraine genes in MO and MA. To date, no studies using NGS in migraine genetics have been published. In order to gain insight into the future possibilities of migraine genetics, we have looked at NGS studies...... and whole genome sequencing gradually become more affordable, these approaches will be used on a larger scale. This may reveal new risk variants in migraine which may offer previously unsuspected biological insights....

  7. Dental caries: Therapeutic possibilities

    Directory of Open Access Journals (Sweden)

    Perić Tamara

    2008-01-01

    Full Text Available Contemporary tendencies in dentistry are based on the concept of maximal protection of healthy tooth tissues. Caries removal has been done traditionally with mechanical rotary instruments that are fast and precise. However, conventional cavity preparation has potential adverse effects to the pulp due to heat, pressure and vibrations. Moreover, drilling often causes pain and requires local anaesthesia, and these procedures are frequently perceived as unpleasant. Etiology, development and prevention of dental caries are better understood today and new restorative materials that bond micromechanically and/or chemically to dental tissues have been introduced. Thus, development of a new, less destructive caries removal technique is allowed. In the last decades, many alternative methods have been introduced in an attempt to replace rotary instruments. These are claimed to be efficient and selective for diseased tissues and to offer comfortable treatment to the patients. New methods include air abrasion, air polishing, ultrasonic, polymer burs, enzymes, systems for chemo-mechanical caries removal, and lasers. The aim of this paper was to discuss various caries removal techniques and possibilities of their use in clinical practice. Based on the literature review it can be concluded that none of the new caries removal methods can completely replace conventional rotary instruments.

  8. Of possible cheminformatics futures

    Science.gov (United States)

    Oprea, Tudor I.; Taboureau, Olivier; Bologa, Cristian G.

    2012-01-01

    For over a decade, cheminformatics has contributed to a wide array of scientific tasks from analytical chemistry and biochemistry to pharmacology and drug discovery; and although its contributions to decision making are recognized, the challenge is how it would contribute to faster development of novel, better products. Here we address the future of cheminformatics with primary focus on innovation. Cheminformatics developers often need to choose between "mainstream" (i.e., accepted, expected) and novel, leading-edge tools, with an increasing trend for open science. Possible futures for cheminformatics include the worst case scenario (lack of funding, no creative usage), as well as the best case scenario (complete integration, from systems biology to virtual physiology). As "-omics" technologies advance, and computer hardware improves, compounds will no longer be profiled at the molecular level, but also in terms of genetic and clinical effects. Among potentially novel tools, we anticipate machine learning models based on free text processing, an increased performance in environmental cheminformatics, significant decision-making support, as well as the emergence of robot scientists conducting automated drug discovery research. Furthermore, cheminformatics is anticipated to expand the frontiers of knowledge and evolve in an open-ended, extensible manner, allowing us to explore multiple research scenarios in order to avoid epistemological "local information minimum trap".

  9. Mammalian cloning: possibilities and threats.

    Science.gov (United States)

    Mitalipov, S M; Wolf, D P

    2000-10-01

    The cloning of mammals originated with the production of limited numbers of genetically identical offspring by blastomere separation or embryo splitting. In the past few years, remarkable progress has been reported in cloning by nuclear transfer (NT) with donor nuclei recovered from embryonic, fetal or adult cells. Factors that contribute to the successful reprogramming of the transferred nucleus and the normal term development of the newly reconstructed embryo include the cell cycle stage of both the donor nucleus and recipient cytoplast, the timing of fusion and cytoplast activation, and the source of donor nuclei. The possibility of producing live offspring by somatic cell NT carries potential applications in animal husbandry, biotechnology, transgenic and pharmaceutical production, biomedical research, and the preservation of endangered species. However, the low efficiencies of cloning by NT coupled with high embryonic, fetal and neonatal losses may restrict immediate commercial applications in agriculture. These limitations notwithstanding, the greatest benefits and practical implications of this new technology could be in transplantation medicine and therapeutic cloning.

  10. Design and experimental application of a novel non-degenerate universal primer set that amplifies prokaryotic 16S rRNA genes with a low possibility to amplify eukaryotic rRNA genes.

    Science.gov (United States)

    Mori, Hiroshi; Maruyama, Fumito; Kato, Hiromi; Toyoda, Atsushi; Dozono, Ayumi; Ohtsubo, Yoshiyuki; Nagata, Yuji; Fujiyama, Asao; Tsuda, Masataka; Kurokawa, Ken

    2014-01-01

    The deep sequencing of 16S rRNA genes amplified by universal primers has revolutionized our understanding of microbial communities by allowing the characterization of the diversity of the uncultured majority. However, some universal primers also amplify eukaryotic rRNA genes, leading to a decrease in the efficiency of sequencing of prokaryotic 16S rRNA genes with possible mischaracterization of the diversity in the microbial community. In this study, we compared 16S rRNA gene sequences from genome-sequenced strains and identified candidates for non-degenerate universal primers that could be used for the amplification of prokaryotic 16S rRNA genes. The 50 identified candidates were investigated to calculate their coverage for prokaryotic and eukaryotic rRNA genes, including those from uncultured taxa and eukaryotic organelles, and a novel universal primer set, 342F-806R, covering many prokaryotic, but not eukaryotic, rRNA genes was identified. This primer set was validated by the amplification of 16S rRNA genes from a soil metagenomic sample and subsequent pyrosequencing using the Roche 454 platform. The same sample was also used for pyrosequencing of the amplicons by employing a commonly used primer set, 338F-533R, and for shotgun metagenomic sequencing using the Illumina platform. Our comparison of the taxonomic compositions inferred by the three sequencing experiments indicated that the non-degenerate 342F-806R primer set can characterize the taxonomic composition of the microbial community without substantial bias, and is highly expected to be applicable to the analysis of a wide variety of microbial communities.

  11. 抗LINGO-1干预促髓鞘重塑在认知损伤中的应用可能%The possible application of anti-LINGO-1 intervention for remyelination in the treatment of cognitive impairment

    Institute of Scientific and Technical Information of China (English)

    吴迪; 汤香; 张志珺(综述)

    2015-01-01

    LINGO-1选择性表达于中枢神经系统(central nervous system,CNS)的少突胶质细胞、少突胶质细胞前体细胞和神经元,在髓鞘损伤性疾病和动物模型中表达升高,通过活化RhoA和抑制Akt磷酸化负性调节少突胶质细胞分化和髓鞘化、神经元存活和轴突再生。抑制LINGO-1功能可有效改善脱髓鞘损伤,维持神经元成活。髓鞘与认知功能关系密切,大量证据表明其损伤可能引起认知功能异常,本综述拟总结抗LINGO-1促髓鞘重塑研究进展并探讨其在认知损伤中应用的可能。%LINGO-1 selectively expressed in the central nervous system (CNS) on oligodendrocytes, oligodendrocyte precursor cells and neurons. Its expression increased in diverse diseases and animal models with myelin injury. LINGO-1 regulates negatively differentiation and myelination of oligodendrocyte, neuronal survive and axonal regeneration with ras homolog gene family member A (RhoA) activating and protein kinase B (Akt) phosphorylation signaling pathways inhibiting. Inhibiting LINGO-1 function could be an effective method for demyelination and impairments of axon with diverse pathogenesis. Myelin is closely associated with cognitive function, and there are many evidences that the myelin breakdown could cause cognitive impairments. The advances of remyelination with anti-LINGO-1 intervention will be summarized, the possible application in cognitive impairments will be discussed in the review.

  12. Meta-avaliação: das abordagens às possibilidades de aplicação Metaevaluación: de los abordajes a las posibilidades de aplicación Metaevaluation: from approaches to possibilities of application

    Directory of Open Access Journals (Sweden)

    Ligia Gomes Elliot

    2011-12-01

    have been accompanied by evaluations that seek to reveal whether the scope of the desired quality was reached. However, the proper conduct of these assessments can be put in check, that is verified by metaevaluations. Metaevaluation was defined as the evaluation of an evaluation. Thus, this paper presents some approaches that represent a variety of contributing authors to conduct metaevaluation. Approaches are applicable to summative and formative metaevaluations. Some examples of metaevaluations already developed are part of the article, which highlights the possibilities of using the last version of international standards of evaluation published by the Joint Committee on Standards for Evaluations.

  13. Possibility expectation and its decision making algorithm

    Science.gov (United States)

    Keller, James M.; Yan, Bolin

    1992-01-01

    The fuzzy integral has been shown to be an effective tool for the aggregation of evidence in decision making. Of primary importance in the development of a fuzzy integral pattern recognition algorithm is the choice (construction) of the measure which embodies the importance of subsets of sources of evidence. Sugeno fuzzy measures have received the most attention due to the recursive nature of the fabrication of the measure on nested sequences of subsets. Possibility measures exhibit an even simpler generation capability, but usually require that one of the sources of information possess complete credibility. In real applications, such normalization may not be possible, or even desirable. In this report, both the theory and a decision making algorithm for a variation of the fuzzy integral are presented. This integral is based on a possibility measure where it is not required that the measure of the universe be unity. A training algorithm for the possibility densities in a pattern recognition application is also presented with the results demonstrated on the shuttle-earth-space training and testing images.

  14. Integrated Seismicity Model to Detect Pairs of Possible Interdependent Earthquakes and Its Application to Aftershocks of the 2011 Tohoku-Oki Earthquake and Sequence of the 2014 Kermadec and Rat Islands Earthquakes

    Science.gov (United States)

    Miyazawa, M.; Tamura, R.

    2015-12-01

    We introduce an integrated seismicity model to stochastically evaluate the time intervals of consecutive earthquakes at global scales, making it possible to detect a pair of earthquakes that are remotely located and possibly related to each other. The model includes seismicity in non-overlapping areas and comprehensively explains the seismicity on the basis of point process models, which include the stationary Poisson model, the aftershock decay model following Omori-Utsu's law, and/or the epidemic-type aftershock sequence (ETAS) model. By use of this model, we examine the possibility of remote triggering of the 2011 M6.4 eastern Shizuoka earthquake in the vicinity of Mt. Fuji that occurred 4 days after the Mw9.0 Tohoku-Oki earthquake and 4 minutes after the M6.2 off-Fukushima earthquake that located about 400 km away, and that of the 2014 Mw7.9 Rat Islands earthquake that occurred within one hour after the Mw6.7 Kermadec earthquake that located about 9,000 km away and followed two large (Mw6.9, 6.5) earthquakes in the region. Both target earthquakes occurred during the passage of surface waves propagating from the previous large events. We estimated probability that the time interval is shorter than that between consecutive events and obtained dynamic stress changes on the faults. The results indicate that the M6.4 eastern Shizuoka event may be rather triggered by the static stress changes from the Tohoku-Oki earthquake and that the Mw7.9 Rat Islands event may have been remotely triggered by the Kermadec events possibly via cyclic fatigue.

  15. Belief Contexts and Epistemic Possibility

    Directory of Open Access Journals (Sweden)

    Hylarie Kochiras

    2006-06-01

    Full Text Available Although epistemic possibility figures in several debates, those debates have had relatively little contact with one another. G. E. Moore focused squarely upon analyzing epistemic uses of the phrase, ‘It’s possible that p’, and in doing so he made two fundamental assumptions. First, he assumed that epistemic possibility statements always express the epistemic position of a community, as opposed to that of an individual speaker. Second, he assumed that all epistemic uses of ‘It’s possible that p’ are analyzable in terms of knowledge, not belief. A number of later theorists, including Keith DeRose, provide alternative accounts of epistemic possibility, while retaining Moore’s two assumptions. Neither assumption has been explicitly challenged, but Jaakko Hintikka’s analysis provides a basis for doing so. Drawing upon Hintikka’s analysis, I argue that some epistemic possibility statements express only the speaker’s individual epistemic state, and that contra DeRose, they are not degenerate community statements but a class in their own right. I further argue that some linguistic contexts are belief- rather than knowledge-based, and in such contexts, what is possible for a speaker depends not upon what she knows, but upon what she believes.

  16. Possibilities to achieve better performance at the Pulp and Paper Industry bark boilers by optimised combustion control. Part 2 General possibilities and applications for four chosen plants; Moejligheter till foerbaettrad drift av skogsindustrins barkpannor genom optimerad foerbraenningsteknisk styrning. Etapp 2 Redovisning av generella moejligheter och tillaempning paa fyra utvalda anlaeggningar

    Energy Technology Data Exchange (ETDEWEB)

    Schuster, Robert; Lundborg, Rickard [AaF-Energi och Miljoe AB, Stockhom (Sweden)

    2000-10-01

    This report presents the result of phase 2 of 'Possibilities to achieve better performance at the Pulp and Paper Industry bark boilers by optimised combustion control'. The project was initiated to generate know-how for coping with the special demands that exist for the bark boilers, with rapid changes of loads and fuel quality. The fuel comprises of different types of wood chips, bark and residue fibres with a wide range of moisture contents. In the future it is expected that these boilers, working under difficult conditions, will have the same environmental requirements as district heating boilers. Phase 1 of the project 'Diagnosis and analysis of existing boilers' was published as SVF report 660. The report contains an analysis of 21 Swedish bark boilers. Phase 3 which has already been started and includes the demonstration and evaluation of modified bark boilers. The report describes and explains different types of suitable boiler modifications, based on four selected typical boilers. The work has included measurements in- and outside the furnace, tests and mathematical simulation in two steps. The first basic simulations was made to get a good picture of the present situation and the later modification simulations to test the practical effects of different combustion solutions. The presentation in the report has been aimed at describing concrete solutions, but most of all to give a better understanding of the hows and whys and the general ways of solving existing problems. The opinions of how to modify a boiler to get the best performance will vary, but the basic chemical-physical laws will remain unchanged. The hope of the authors is that this report will serve as a basis for choosing between proposed different solutions and to inspire engineers and owners to modify bark boilers using the technology of tomorrow.

  17. Unconventional pairing in doped band insulators on a honeycomb lattice: the role of the disconnected Fermi surface and a possible application to superconducting β-MNCl (M=Hf, Zr

    Directory of Open Access Journals (Sweden)

    Kazuhiko Kuroki

    2008-01-01

    Full Text Available We investigate the possibility of realizing unconventional superconductivity in doped band insulators on the square and honeycomb lattices. The latter lattice is found to be a good candidate due to the disconnectivity of the Fermi surface. We propose applying the theory to the superconductivity in doped layered nitride β-MNCl (M= Hf, Zr. Finally, we compare two groups of superconductors with disconnected Fermi surface, β-MNCl and the iron pnictides, which have high critical temperature Tc, despite some faults against superconductivity are present.

  18. Unconventional pairing in doped band insulators on a honeycomb lattice: the role of the disconnected Fermi surface and a possible application to superconducting β-MNCl (M=Hf, Zr).

    Science.gov (United States)

    Kuroki, Kazuhiko

    2008-12-01

    We investigate the possibility of realizing unconventional superconductivity in doped band insulators on the square and honeycomb lattices. The latter lattice is found to be a good candidate due to the disconnectivity of the Fermi surface. We propose applying the theory to the superconductivity in doped layered nitride β-MNCl (M= Hf, Zr). Finally, we compare two groups of superconductors with disconnected Fermi surface, β-MNCl and the iron pnictides, which have high critical temperature Tc, despite some faults against superconductivity are present.

  19. Estimating Terrorist Risk with Possibility Theory

    Energy Technology Data Exchange (ETDEWEB)

    J.L. Darby

    2004-11-30

    This report summarizes techniques that use possibility theory to estimate the risk of terrorist acts. These techniques were developed under the sponsorship of the Department of Homeland Security (DHS) as part of the National Infrastructure Simulation Analysis Center (NISAC) project. The techniques have been used to estimate the risk of various terrorist scenarios to support NISAC analyses during 2004. The techniques are based on the Logic Evolved Decision (LED) methodology developed over the past few years by Terry Bott and Steve Eisenhawer at LANL. [LED] The LED methodology involves the use of fuzzy sets, possibility theory, and approximate reasoning. LED captures the uncertainty due to vagueness and imprecision that is inherent in the fidelity of the information available for terrorist acts; probability theory cannot capture these uncertainties. This report does not address the philosophy supporting the development of nonprobabilistic approaches, and it does not discuss possibility theory in detail. The references provide a detailed discussion of these subjects. [Shafer] [Klir and Yuan] [Dubois and Prade] Suffice to say that these approaches were developed to address types of uncertainty that cannot be addressed by a probability measure. An earlier report discussed in detail the problems with using a probability measure to evaluate terrorist risk. [Darby Methodology]. Two related techniques are discussed in this report: (1) a numerical technique, and (2) a linguistic technique. The numerical technique uses traditional possibility theory applied to crisp sets, while the linguistic technique applies possibility theory to fuzzy sets. Both of these techniques as applied to terrorist risk for NISAC applications are implemented in software called PossibleRisk. The techniques implemented in PossibleRisk were developed specifically for use in estimating terrorist risk for the NISAC program. The LEDTools code can be used to perform the same linguistic evaluation as

  20. Degradation of the remanent ferromagnetic state under the action of ferroelectric relaxation processes in Co/(1-x)PMN-xPT/Co hybrids: Possible implications on cryogenic and room-temperature applications

    Science.gov (United States)

    Stamopoulos, D.; Zeibekis, M.; Vertsioti, G.; Zhang, S. J.

    2014-08-01

    Low-dimensional hybrid structures of heterogeneous constituents usually exhibit abnormal properties, a fact that makes such hybrids attractive for various cryogenic and room-temperature applications. Here, we studied Co/(1 - x)Pb(Mg1/3Nb2/3)O3-xPbTiO3/Co (Co/PMN-xPT/Co) with x = 0.29 and 0.30, specifically focusing on the evolution of the remanent ferromagnetic state, mrem of the Co outer layers in the whole temperature range from 300 K down to 10 K, upon application of an external electric field, Eex. We observed that mrem was vulnerable to degradation through the occurrence of electric field-induced magnetic instabilities (EMIs) that appeared only when Eex ≠ 0 kV/cm and were facilitated as Eex increases. However, EMIs completely ceased below a characteristic temperature Tces = 170 K even for the maximum |Eex| = 5 kV/cm applied in this work. A direct comparison of the magnetization data of the Co/PMN-xPT/Co hybrids reported here with the electromechanical properties of the parent PMN-xPT crystals plausibly indicates that EMIs are motivated by the coupling of the ferromagnetic domains of the Co outer layers with the ferroelectric domains of the PMN-xPT crystal. These results highlight the drawback of EMIs in relevant hybrids and delimit the temperature regime for the reliable operation of the Co/PMN-xPT/Co ones studied here.

  1. Improving tomato seed quality- challenges and possibilities

    DEFF Research Database (Denmark)

    Shrestha, Santosh

    2017-01-01

    The thesis investigates the possibility of using single seed near-infrared (NIR) spectroscopy, multispectral imaging (MSI) and NIR hyperspectral imaging (NIR-HSI) in combination with chemometrics for rapid determination of the tomato seed quality. The results of the PhD study are compiled in four...... manuscripts (MS). These non-destructive methods show the potential of sorting tomato seeds as per their viability and varietal identity. The results are discussed in the context of possible contribution from these methods in the improvement of the seed quality in Nepal. In MS I, potential application of NIR...... spectroscopy in combination with chemometrics for prediction of tomato seed viability is demonstrated. The work in MS I also emphasises on identifying the important NIR spectral regions for the chemometric model that are relevant to the separation of viable and non-viable seeds. The NIR-HIS method was also...

  2. Regulation possibilities of biomass combustion

    Science.gov (United States)

    Suzdalenko, Vera; Gedrovics, Martins; Zake, Maija; Barmina, Inesa

    2012-11-01

    The focus of the recent experimental research is to analyze the regulation possibilities of biomass combustion. Three possibilities were chosen as part of this research: a) biomass cofiring with propane, b) swirling flow with re-circulation zone, and c) use of a permanent magnet. The aim of the research is to provide stable, controllable and effective biomass combustion with minimum emissions. The special pilot device was created where biomass can be combusted separately and co-fired with propane. Wood pellets were used during the experiments.

  3. Propagation des ondes élastiques dans les matériaux non linéaires Aperçu des résultats de laboratoire obtenus sur les roches et des applications possibles en géophysique Propagation of Elastic Waves in Nonlinear Materials Survey of Laboratory Results on Rock and Geophysical Applications

    Directory of Open Access Journals (Sweden)

    Rasolofosaon P.

    2006-12-01

    non-linéarité sous fort confinement, et qui pourraient engendrer un signal résultant d'une interaction onde-onde . Tempérant ce pessimisme, il faut noter qu'un éventuel signal d'interaction non linéaire présenterait l'avantage, quant à sa détection, d'être dans une bande de fréquence différente de celle des ondes utilisées pour l'engendrer. Bien que nous n'ayons pas connaissance d'essais d'application actuels, les perspectives paraissent plus encourageantes dans le domaine du génie civil ou minier. C'est dans le domaine diagraphique, où des distances de propagation sont très faibles, que des applications semblent possibles à moyen terme. Si l'on en juge par le dépôt très récent de plusieurs brevets, les compagnies de logging poursuivraient des recherches dans cette voie. A general and important characteristic of rocks is their elastically nonlinear behavior resulting in significant effects on wave propagation. The nonlinear response of rock is a direct consequence of the compliant nature of rock : the macro-and micro-structure of the material (microcracks, grain-to-grain contacts, etc. . As a result, the material modulus varies as a function of the applied pressure. Interest has grown significantly in the last several years, as illustrated by the increasing number of publications regarding this topic. Here we present a summary of the fundamentals of theory and of experimental observations characteristic of rock, and we address possible applications in geophysics. Two disciplines regarding the nonlinear elasticity of rock have been developed over recent years in tandem :- Acoustoelasticity where wave propagation in statically, prestressed materials is studied. Here one relates the variation in applied pressure to the elastic wavespeed in order to extract the nonlinear coefficients. This area of study includes the topic of stress-induced anisotropy. - Acoustic nonlinearity where we are interested in the temporary and local variation in the elastic

  4. Pharmacogenomics and migraine: possible implications

    DEFF Research Database (Denmark)

    Tfelt-Hansen, P.; Brosen, K.

    2008-01-01

    cases pharmacodynamic variability we mention possible implications for the acute and preventive treatment of migraine. Pharmacogenomics will most likely in the future be one part of our therapeutic armamentarium and will provide a stronger scientific basis for optimizing drug therapy on the basis...

  5. A glorious, yet almost forgotten, mathematical theory, and some possibly new applications of it to physics; Una gloriosa ma quasi dimenticata teoria matematica e certe sue inedite applicazioni alla fisica

    Energy Technology Data Exchange (ETDEWEB)

    Lo Surdo, C. [ENEA, Divisione Fusione Centro Ricerche Frascati, Rome (Italy)

    2001-07-01

    Hardly the role and the importance of Classical-Invariant Theory is the history of mathematics (say, between - 1850 and - 1920) can be fully appreciated by a nonspecialist. In this study, it was firstly purposed to provide a compact sketch of its foundations starting from (and keeping the framework of) some very basic ideas in the equation theory; and then, after reviewing a couple of classical examples, to illustrate a number of (presumably new) applications to physics, with special reference to constitutive relations in continuous material media. As a significant example of the latter type (amongst other ones), it shall be completely worked out the problem of the a priori structure of linear viscous-stress tensor in a magnetoplasma. [Italian] Non e' facile, da parte del non-specialista, apprezzare pienamente il ruolo e l'importanza della Teoria degli Invarianti Classici nella storia della matematica (diciamo all'incirca tra il 1850 e il 1920). In questo studio, il lettore trova anzitutto una rassegna, succinta ma largamente improntata alla generalita', dei suoi fondamenti a partire da poche idee di base della teoria delle equazioni, oltre ad un breve inquadramento storico e alla illustrazione di un paio di esempi classici. Seguono poi alcune applicazion - presuntivamente nuove - alla fisica matematica, con particolare riferimento alle relazioni costitutive in mezzi materiali continui. Come significativo esempio di applicazione di quest'ultimo tipo, e' infine completamente sviluppato il calcolo della struttura a priori del tensore di viscosita' lineare in un magnetoplasma.

  6. Determination of GHB in human hair by HPLC-MS/MS: Development and validation of a method and application to a study group and three possible single exposure cases.

    Science.gov (United States)

    Bertol, Elisabetta; Mari, Francesco; Vaiano, Fabio; Romano, Guido; Zaami, Simona; Baglìo, Giovanni; Busardò, Francesco Paolo

    2015-05-01

    Gamma-hydroxybutyrate (GHB) over the last two decades has generated increased notoriety as a euphoric and disinhibiting drug of abuse in cases of drug-related sexual assault and for this reason it is considered a 'date rape' drug. The first aim of this paper was to develop and fully validate a method for the detection of GHB in human hair by high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) after liquid-liquid extraction (LLE). The second aim was the application of the method to hair samples of 30 GHB-free users in order to determine the basal level. The results obtained showed no significant differences in endogenous concentrations (p = 0.556) between hair samples of the three groups (black, blonde, and dyed hair) and the age and sex of the subjects did not affect the endogenous levels. Another 12 healthy volunteers, with no previous history of GHB use, were selected and a single dose (25 mg/Kg) was orally administered to all of them and hair samples were collected before the administration of the single dose and other two samples were collected one month and two months later, respectively. The segmental analysis of the latter two samples allowed us to calculate two ratios: 4.45:1 (95% C.I. 3.52-5.63) and 3.35:1 (95% C.I. 2.14-5.18), respectively, which can be recommended as reasonable values for a positive identification of GHB intake. Finally the method was applied to three real cases where a GHB single exposure probably occurred.

  7. Sign reversal of junction magnetoresistance in p-La0.7Ca0.3MnO3/SiO2/n-Si heterostructure: a possibility in spintronics application.

    Science.gov (United States)

    Giri, S K; Nath, T K

    2012-10-01

    We have fabricated a p-La0.7Ca0.3MnO3/SiO2/n-Si heterostructure, consisting of a p-type manganite (La0.7Ca0.3MnO3) and n-type Si with a interfacial layer of SiO2 with typical thickness of about 9 nm using pulsed laser deposition technique. The junction exhibits rectifying behavior over the temperature range of 10-300 K with rectification factor 52 at room temperature. Investigation on the electrical properties of p-La0.7Ca0.3MnO3/SiO2/n-Si heterostructure exhibits nonlinear J-V characteristics in a wide temperature range. A crossover from negative to positive junction magnetoresistance (JMR) is observed in p-La0.7Ca0.3MnO3/SiO2/n-Si heterostructure in current perpendicular to film plane (CPP) geometry. The temperature dependent sign of junction magnetoresistance of the heterojunction has been investigated carefully in details. It is found that the junction exhibits the positive junction magnetoresistance when the temperature is greater than the ferromagnetic to paramagnetic transition temperature (Tc) of the top highly spin-polarized half-metallic ferromagnetic La0.7Ca0.3MnO3 manganite film layer. The relation between junction magnetoresistance and external magnetic field is found to be of (delta rho/rho approximately equal alphaHbeta) type having both alpha and beta temperature dependent. We attribute the emergence of negative JMR at lower temperature ( Tc) to the quantum mechanical tunneling transport mechanism across the heterojunction. Our results might be very useful to fabricate artificial devices using the manganite-based heterojunction grown on single crystalline n-Si (100) in spintronics device applications.

  8. MOBILE LEARING - possibilities and perspectives

    DEFF Research Database (Denmark)

    Larsen, Lasse Juel

    2009-01-01

    This paper proposes that SMS (Short Message Service) or text-messaging on mobile devices can serve as an extension or possible create another way of learning traditional scholastic content normally associated with the school system. The potential of the SMS is still very much untapped and largely...... unexplored as a pedagogical tool within teaching and learning domains. This paper is inspired by locative arts and ongoing experiments regarding not only SMS based pervasive systems, but also the more complex usage of mobile devices in investigating urban living conditions and experiences both existentially...... and as an exploring mechanism of the cityscape. This paper aims at discussing the potentials and outlining the possibilities for mobile learning in the traditional school setting. The complexity of these issues derives not only from the traditions of the school system, but also from diverging perspectives...

  9. Possible climates on terrestrial exoplanets

    CERN Document Server

    Forget, Francois

    2013-01-01

    What kind of environment may exist on terrestrial planets around other stars? In spite of the lack of direct observations, it may not be premature to speculate on exoplanetary climates, for instance to optimize future telescopic observations, or to assess the probability of habitable worlds. To first order, climate primarily depends on 1) The atmospheric composition and the volatile inventory; 2) The incident stellar flux; 3) The tidal evolution of the planetary spin, which can notably lock a planet with a permanent night side. The atmospheric composition and mass depends on complex processes which are difficult to model: origins of volatile, atmospheric escape, geochemistry, photochemistry. We discuss physical constraints which can help us to speculate on the possible type of atmosphere, depending on the planet size, its final distance for its star and the star type. Assuming that the atmosphere is known, the possible climates can be explored using Global Climate Models analogous to the ones developed to sim...

  10. Clifford Fibrations and Possible Kinematics

    Science.gov (United States)

    McRae, Alan S.

    2009-07-01

    Following Herranz and Santander [Herranz F.J., Santander M., Mem. Real Acad. Cienc. Exact. Fis. Natur. Madrid 32 (1998), 59-84, physics/9702030] we will construct homogeneous spaces based on possible kinematical algebras and groups [Bacry H., Levy-Leblond J.-M., J. Math. Phys. 9 (1967), 1605-1614] and their contractions for 2-dimensional spacetimes. Our construction is different in that it is based on a generalized Clifford fibration: Following Penrose [Penrose R., Alfred A. Knopf, Inc., New York, 2005] we will call our fibration a Clifford fibration and not a Hopf fibration, as our fibration is a geometrical construction. The simple algebraic properties of the fibration describe the geometrical properties of the kinematical algebras and groups as well as the spacetimes that are derived from them. We develop an algebraic framework that handles all possible kinematic algebras save one, the static algebra.

  11. Another possible energy landscape; Un autre paysage energetique possible

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-06-01

    This analysis presents the national energy balances from the national energy accounting. The first part presents the accounting analysis on the electric power consumption and production in France. The second part deals with the global energy accounting, for the energy sources and utilization, together. From these analysis the authors show how the global energy efficiency of production and utilization is possible. Solutions allowing the reduction of the non renewable energies consumption and solution for the nuclear power phaseout are also proposed. (A.L.B.)

  12. Investigating How an Artificial Neural Network Model Can Be Used to Detect Added Mass on a Non-Rotating Beam Using Its Natural Frequencies: A Possible Application for Wind Turbine Blade Ice Detection

    Directory of Open Access Journals (Sweden)

    Sudhakar Gantasala

    2017-02-01

    Full Text Available Structures vibrate with their natural frequencies when disturbed from their equilibrium position. These frequencies reduce when an additional mass accumulates on their structures, like ice accumulation on wind turbines installed in cold climate sites. The added mass has two features: the location and quantity of mass. Natural frequencies of the structure reduce differently depending on these two features of the added mass. In this work, a technique based on an artificial neural network (ANN model is proposed to identify added mass by training the neural network with a dataset of natural frequencies of the structure calculated using different quantities of the added mass at different locations on the structure. The proposed method is demonstrated on a non-rotating beam model fixed at one end. The length of the beam is divided into three zones in which different added masses are considered, and its natural frequencies are calculated using a finite element model of the beam. ANN is trained with this dataset of natural frequencies of the beam as an input and corresponding added masses used in the calculations as an output. ANN approximates the non-linear relationship between these inputs and outputs. An experimental setup of the cantilever beam is fabricated, and experimental modal analysis is carried out considering a few added masses on the beam. The frequencies estimated in the experiments are given as an input to the trained ANN model, and the identified masses are compared against the actual masses used in the experiments. These masses are identified with an error that varies with the location and the quantity of added mass. The reason for these errors can be attributed to the unaccounted stiffness variation in the beam model due to the added mass while generating the dataset for training the neural network. Therefore, the added masses are roughly estimated. At the end of the paper, an application of the current technique for detecting ice mass

  13. Possibility and safety of application of misoprostol in the induction of pregnant women with pre-eclampsia%米索前列醇用于先兆子痫引产的可行性及安全性研究

    Institute of Scientific and Technical Information of China (English)

    崔秀娟; 李金风

    2001-01-01

    目的:探讨米索前列醇用于先兆子痫终止妊娠的可行性及对母儿的安全性,同时观察产时使用硫酸镁对产程和产后出血的影响。方法:将62例先兆子痫有引产指征,单胎头位无宫缩的初产妇随机分为两组,研究组32例、对照组30例,分别用米索前列醇和催产素引产。两组产妇应用硫酸镁的情况无差异。结果:引产总有效率研究组为96.9%,对照组为73.3%,差异有显著性(P<0.01)。剖宫产率研究组为18.8%,对照组为46.7%,差异有显著性(P<0.01)。产时应用硫酸镁可引起潜伏期时间延长,而总产程时间无明显增加(P>0.05)。产后出血量无显著差异(P>0.05)。结论:米索前列醇阴道置药用于先兆子痫引产,疗效显著且安全、方便,有推广价值。%Objective: To investigate the possibility and safety of misoprostol to end gestation for pre-eclampsia and to observe the effect of magnesium sulphate (MgSO4) on the bleeding in and after dilivery. Methods: 62 primiparas with pre-eclampsia, singal pregnant, vertex present were selected. All cases had indications for labor induction. The 62 women were randomly divided into two groups.32 cases used misoprostol for induction was the study group. 30 cases used oxytocin served as the control group. The use of magnesium sulphate during birth timewas no difference between the two groups. Results: The total effectual rate of induced labor was 96.9% in study group, and 73.3% in control group,there was significant difference between them(P<0.01).The rate of cesarean section of the study group (18.8%) was significantly higher than that of the control group (46.7%) (P<0.01). Theincubation period of puerpera used magnesium sulphate was obviously longer thanthat of those who didn't take magnesium sulphate(P<0.05). But the total dilivery time didn't prolong (P>0.05). There was no difference in the volume of postpartum bleeding between two groups (P

  14. Código de barras del ADN y sus posibles aplicaciones en el campo de la Entomología DNA barcoding and its possible applications to the field of Entomology

    Directory of Open Access Journals (Sweden)

    Analía A. Lanteri

    2007-12-01

    Full Text Available En este artículo se abordan algunos aspectos de la controversia sobre la iniciativa «Código de barras del ADN», y se hace hincapié en sus potenciales aplicaciones en Entomología. Esta iniciativa propone emplear información dentro de una misma región génica (gen mitocondrial de la Citocromo c Oxidasa I = COI, en todas las especies vivientes y con condiciones de secuenciación universalmente aceptadas y estandarizadas. En la actualidad, no pretende sustituir la taxonomía alfa y la filogenia sino agilizar las tareas de identificación, especialmente en el campo de la Biomedicina (identificación de patógenos, parásitos y vectores, el control de plagas (intercepción de especies invasoras, cualquiera sea su estado de desarrollo ontogenético y los estudios sobre conservación de la biodiversidad. Para arribar a una correcta delimitación de las especies biológicas es preciso contar con las secuencias de COI de numerosos individuos a lo largo de todo su rango geográfico y además, secuencias de genes nucleares e información morfológica y biológica detallada. Las «Unidades Evolutivas Significativas», identificadas sobre la base del «código de barras», podrían corresponder tanto a morfoespecies como a especies crípticas y a subespecies o linajes con diferentes preferencias de huéspedes. La integración del «código de barras del ADN», el trabajo de campo, las colecciones de museos y la investigación científica resultan imprescindibles para que esta herramienta redunde en avances significativos en el campo de la Sistemática Entomológica.This article deals with some of the most controversial issues of the DNA barcode initiative, focusing on its potential applications to Entomology. The barcoding proposes using information within the same gene region (Cytocrome c Oxidase I= COI mitochondrial gene, in all living species and under standard conditions of sequencing. At present, it does not attempt to replace alpha taxonomy or

  15. On the Possibility of Supertasks

    Directory of Open Access Journals (Sweden)

    Ahmet Çevik

    2013-06-01

    Full Text Available Supertask, a notion in analytic philosophy, is the process of performing infinite number of operations in a finite amount of time. In this article, we argue about the logical possibility of performing a supertask with a focus on the analysis of S.C. Chihara’s discussion paper, and we try to find answers for his questions from a mathematical point of view. In the later sections of the paper, we give some known supertask models in philosophy and mathematics.

  16. Amazon: Is Profitability a Possibility?

    Directory of Open Access Journals (Sweden)

    Brett DENNIS

    2014-06-01

    Full Text Available In today’s society, companies seem to all be following the same trend; growth in profitability at all cost. Higher profits, for the most part, leads to more investors and more potential financing. Amazon.com appears to be breaking that trend, however. Their strategy seems to be growth, but not in profits. We would like to look into how and why Amazon is growing at such a fast pace, while their profits are staying steady at a very low level. Is profitability a possibility for Amazon? We believe that a marginal increase in price could accomplish just that, with a minimal impact to consumers.

  17. [Possibilities of psychoprophylaxis in epilepsy].

    Science.gov (United States)

    Bilikiewicz, A

    1976-01-01

    The psychiatrist should be given also their share in the prevetion of epilepsy by means of raising the psychiatric culture of the society and teaching the population the principles of mental hygiene and psychoprophylaxia. The possibilities of psychiatry in prophylactic management of patients with developed epilepsy include: 1. Energetic measures for controlling attacks which has many psychoprophylactic aspects. 2. Prevention of psychotraumatizing situations leading to secondary neurotic, psychotic and other reactions and behaviour disorders of the type of homilopathy and sociopathy, 3. Counteracting the development of mental and social disability in epileptics. Treatment of epilepsy should be conducted from its very beginning in cooperation with psychiatrists and therapeutic psychologists. The probems of prophylaxis cannot be separated from prophylactic treatment, psychotherapy sociotherapy and rehabilitation.

  18. Moving from objects to possibilities

    DEFF Research Database (Denmark)

    Donovan, Jared; Gunn, Wendy

    2012-01-01

    and controls that determine indoor climate. A central issue in relating perceptions and experiences of indoor climate to wider structures and systems is finding ways of supporting company, university partners and users to imagine possibilities instead of certainties in terms of innovation potential. Whereas......, researchers and industry partners working in the field of indoor climate emphasize identifiable, measurable, parameters of comfort and focus their efforts on engineering products and systems based upon behavioural models, as researchers interested in the notion of participatory innovation, we engage...... contexts of learning? What role do design materials play in helping researchers and users make sense of the intangible qualities of perceiving indoor climate? and How do partial understandings and sense making gained through material investigations build a relation between practices of designing and using?...

  19. Nano-photocatalytic materials: possibilities and challenges.

    Science.gov (United States)

    Tong, Hua; Ouyang, Shuxin; Bi, Yingpu; Umezawa, Naoto; Oshikiri, Mitsutake; Ye, Jinhua

    2012-01-10

    Semiconductor photocatalysis has received much attention as a potential solution to the worldwide energy shortage and for counteracting environmental degradation. This article reviews state-of-the-art research activities in the field, focusing on the scientific and technological possibilities offered by photocatalytic materials. We begin with a survey of efforts to explore suitable materials and to optimize their energy band configurations for specific applications. We then examine the design and fabrication of advanced photocatalytic materials in the framework of nanotechnology. Many of the most recent advances in photocatalysis have been realized by selective control of the morphology of nanomaterials or by utilizing the collective properties of nano-assembly systems. Finally, we discuss the current theoretical understanding of key aspects of photocatalytic materials. This review also highlights crucial issues that should be addressed in future research activities.

  20. Biophysical Study of Archaebacteria Biomembrane and Possible Application in Biomaterials.

    Science.gov (United States)

    1991-12-31

    arrangement of the protonated Schiff base , AsP-85, Asp-212 and Arg-82 in agreement with an electron diffraction derived model (3,9,20,27). The disruption of...this active site upon formation of the M intermediate due to protonation of Asp-85 from the Schiff base is believed to cause ejection of a proton...Asp- 96 to the Schiff base (20). 2. Development of new biophysical techniques to study Archaebacteria membrane proteins: An important aspect of the

  1. Application possibilities of plasmas generated by high power laser ablation

    OpenAIRE

    Torrisi, L.

    2009-01-01

    High-power pulsed lasers emitting IR and visible radiation with intensities ranging between 10^8 and 10^16 W/cm2, pulse duration from 0.4 to 9 ns and energy from 100 mJ up to 600 J, operating in single mode or in repetition rate, can be employed to produce non-equilibrium plasma in vacuum by irradiating solid targets. Such a laser-produced plasma generates highly charged and high-energy ions of various elements, as well as soft and hard X-ray radiations. Heavy ions with charge state up to 58+...

  2. Bamboo: An Underutilized Resource with Extensive Application Possibilities.

    Science.gov (United States)

    Bamboo is classified into Subtribe Bambusoideae of the Poaceae family which is comprised of over 1600 species of bamboo. Most species originated in Asia and Central and South America, although there are several species native to the United States. Often overlooked in the United States, bamboo is g...

  3. Possible application of brewer's spent grain in biotechnology

    OpenAIRE

    Pejin Jelena D.; Radosavljević Miloš S.; Grujić Olgica S.; Mojović Ljiljana V.; Kocić-Tanackov Sunčica D.; Nikolić Svetlana B.; Đukić-Vuković Aleksandra J.

    2013-01-01

    Brewer’s spent grain is the major by-product in beer production. It is produced in large quantities (20 kg per 100 liters of produced beer) throughout the year at a low cost or no cost, and due to its high protein and carbohydrates content it can be used as a raw material in biotechnology. Biotechnological processes based on renewable agro-industrial by-products have ecological (zero CO2 emission, eco-friendly by-products) and economical (cheap raw materials and reduction of storage cos...

  4. Whey proteins-Properties and Possibility of Application

    Directory of Open Access Journals (Sweden)

    Snežana Jovanović

    2005-07-01

    Full Text Available Proteini mliječnog seruma predstavljaju 18-20% ukupnih dušikovih tvari mlijeka. Dominantni serum protein je β-laktoglobulin, dok je α-laktalbumin zastupljen s oko 20%, odnosno 2-5% od ukupnih dušikovih tvari mlijeka. Serum proteini su osjetljivi na djelovanje topline; ireverzibilno denaturiraju i koaguliraju pri djelovanju visokih temperatura. Djelovanje visokih temperatura uzrokuje kemijske interakcije među proteinima mlijeka, a posebno između α-laktalbumina, β-laktoglobulina i κ-kazeina. Kompleksi koji se ostvaruju među njima poznati su pod nazivom koagregati proteina mlijeka. Od osamdesetih godina prošlog stoljeća, serum proteini značajni su i kao nutritivni i kao funkcionalni aditivi. Serum proteini imaju dobre funkcionalne osobine. Mogu se koristiti kao sredstva za želiranje, za vezivanje vode, emulgiranje i obrazovanje pjene. Zahvaljujući primjeni membranskih tehnika frakcioniranja, danas je moguće proizvesti različite aditive na bazi serum proteina. Najvažniji proizvodi na bazi proteina sirutke su: proteinski koncentrati, izolati i hidrolizati proteina sirutke. U ovom su radu prikaz ane osobine dominantnih proteina sirutke i njihova moguća primjena u industriji mlijeka.

  5. Selected Papers on Low-Energy Antiprotons and Possible Applications

    Energy Technology Data Exchange (ETDEWEB)

    Noble, Robert [Fermilab

    1998-09-19

    The only realistic means by which to create a facility at Fermilab to produce large amounts of low energy antiprotons is to use resources which already exist. There is simply too little money and manpower at this point in time to generate new accelerators on a time scale before the turn of the century. Therefore, innovation is required to modify existing equipment to provide the services required by experimenters.

  6. Possible Applications of 3D Printing Technology on Textile Substrates

    Science.gov (United States)

    Korger, M.; Bergschneider, J.; Lutz, M.; Mahltig, B.; Finsterbusch, K.; Rabe, M.

    2016-07-01

    3D printing is a rapidly emerging additive manufacturing technology which can offer cost efficiency and flexibility in product development and production. In textile production 3D printing can also serve as an add-on process to apply 3D structures on textiles. In this study the low-cost fused deposition modeling (FDM) technique was applied using different thermoplastic printing materials available on the market with focus on flexible filaments such as thermoplastic elastomers (TPE) or Soft PLA. Since a good adhesion and stability of the 3D printed structures on textiles are essential, separation force and abrasion resistance tests were conducted with different kinds of printed woven fabrics demonstrating that a sufficient adhesion can be achieved. The main influencing factor can be attributed to the topography of the textile surface affected by the weave, roughness and hairiness offering formlocking connections followed by the wettability of the textile surface by the molten polymer, which depends on the textile surface energy and can be specifically controlled by washing (desizing), finishing or plasma treatment of the textile before the print. These basic adhesion mechanisms can also be considered crucial for 3D printing on knitwear.

  7. BLENDED LEARNING: POSSIBILITIES APPLICATION IN THE TECHNOLOGICAL UNIVERSITY OF CANCUN

    OpenAIRE

    Pérez De la Cruz, Antonio; Universidad Tecnológica de Cancún

    2014-01-01

    At present the present time the skill related to the Technologies of Information and Communication (TIC´s) acquiere every day more importance in the contribution to business success, mainly in the area of formation of human capital, in which in-line education trends. For this reason, the universities must begin to implement education model in-line learning, combined with the actual clases, with the objective that the students acquire experience in the use of the TIC´s. In consecuence, the pre...

  8. Ethnography in Counseling Psychology Research: Possibilities for Application

    Science.gov (United States)

    Suzuki, Lisa A.; Ahluwalia, Muninder K.; Mattis, Jacqueline S.; Quizon, Cherubim A.

    2005-01-01

    The emphasis placed on prolonged engagement, fieldwork, and participant observation has prevented wide-scale use of ethnography in counseling psychology. This article provides a discussion of ethnography in terms of definition, process, and potential ethical dilemmas. The authors propose that ethnographically informed methods can enhance…

  9. Inelastic scattering of neutrons and possible biological applications.

    Science.gov (United States)

    Egelstaff, P A

    1976-05-01

    The field of neutron inelastic scattering has probably been developed to the stage where it can begin to help the biologist. Because essentially no experimental data have been obtained, it is difficult either to draw conclusions or to make forecasts except on the basis of general hypotheses. It seems likely, however, that the next stage is up to biologists. After reviewing those biological problems in which molecular dynamics might play an important role, they should suggest specimens of interest which can give inelastic peaks with existing spectrometers operating with 5 to 10-A neutrons at angles greater than 5degrees and with resolutions of approximately 50 mueV. These specimens may involve molecules slightly smaller and more mobile than some biologists would like, but a successful outcome might lead to the development of spectrometers capable of working in a more satisfactory range. In this event the return may well prove rewarding to the biologists.

  10. Chicken antimicrobial peptides: biological functions and possible applications

    NARCIS (Netherlands)

    Dijk, Albert van

    2007-01-01

    Farm animals often suffer from diseases of the gastro-intestinal tract. Modulation of natural defence mechanisms by dietary additives may be one way to improve intestinal health and food safety. In mammals, antimicrobial peptides (AMPs) play an important role in the host defence of skin and mucosal

  11. Uncertainty Relations and Possible Experience

    Directory of Open Access Journals (Sweden)

    Gregg Jaeger

    2016-06-01

    Full Text Available The uncertainty principle can be understood as a condition of joint indeterminacy of classes of properties in quantum theory. The mathematical expressions most closely associated with this principle have been the uncertainty relations, various inequalities exemplified by the well known expression regarding position and momentum introduced by Heisenberg. Here, recent work involving a new sort of “logical” indeterminacy principle and associated relations introduced by Pitowsky, expressable directly in terms of probabilities of outcomes of measurements of sharp quantum observables, is reviewed and its quantum nature is discussed. These novel relations are derivable from Boolean “conditions of possible experience” of the quantum realm and have been considered both as fundamentally logical and as fundamentally geometrical. This work focuses on the relationship of indeterminacy to the propositions regarding the values of discrete, sharp observables of quantum systems. Here, reasons for favoring each of these two positions are considered. Finally, with an eye toward future research related to indeterminacy relations, further novel approaches grounded in category theory and intended to capture and reconceptualize the complementarity characteristics of quantum propositions are discussed in relation to the former.

  12. Possibilities of Engineering Ethics Education

    Science.gov (United States)

    Matsuki, Junya

    This paper discusses the possibilities of teaching engineering ethics in universities. This is based on the teaching experience of a newly developed course that has been introduced to the Department of Electrical and Electronic Engineering at the University of Fukui, since April 2004. Entitled “ethics for engineers”, the course targeted senior-level students and makes use of a newly written textbook that emphasizes social aspects of science and technology. To encourage students to think and form their own opinions with regards to their role as engineers in a modern technological society, the book is complemented by other materials such as videos, newspaper articles and some other relevant books. Students are also encouraged to write reports that reflect their own opinion on subjects such as what kind of engineers they intend to be, or what do ethics mean to them? The paper will conclude by giving a course evaluation including students' response, highlighting valuable experiences and stating the importance of further developing this topic in engineering education.

  13. [Dental caries--therapeutic possibilities].

    Science.gov (United States)

    Perić, Tamara; Marković, Dejan; Zivković, Slavoljub

    2008-01-01

    Contemporary tendencies in dentistry are based on the concept of maximal protection of healthy tooth tissues. Caries removal has been done traditionally with mechanical rotary instruments that are fast and precise. However, conventional cavity preparation has potential adverse effects to the pulp due to heat, pressure and vibrations. Moreover, drilling often causes pain and requires local anaesthesia, and these procedures are frequently perceived as unpleasant. Etiology, development and prevention of dental caries are better understood today and new restorative materials that bond micromechanically and/or chemically to dental tissues have been introduced. Thus, development of a new, less destructive caries removal technique is allowed. In the last decades, many alternative methods have been introduced in an attempt to replace rotary instruments. These are claimed to be efficient and selective for diseased tissues and to offer comfortable treatment to the patients. New methods include air abrasion, air polishing, ultrasonic, polymer burs, enzymes, systems for chemo-mechanical caries removal, and lasers. The aim of this paper was to discuss various caries removal techniques and possibilities of their use in clinical practice. Based on the literature review it can be concluded that none of the new caries removal methods can completely replace conventional rotary instruments.

  14. Bioplastics: Development, Possibilities and Difficulties

    Directory of Open Access Journals (Sweden)

    Aistė Karpušenkaitė

    2014-07-01

    Full Text Available New possible ways of plastics manufacture and waste treatment are being searched when trying to tackle the problems related to the growth of waste quantities and decline in non-renewable resources. Presently, the most promising and effective way to solve the mentioned problems is production of bioplastics, but its way to recognition is very slow. One of the barriers is the absence of clear and united opinion throughout the EU Arising new discussions about biodegradable and biobased plastics will allow responsible authorities to update and adapt the legal law, which now almost does not include any reglement on bioplastics production and usage. The other issues of bioplastics are social aspects as this material can be made of primal food sources like crops, and the ecological ones because of their unknown effects on human health and the environment. Nevertheless, the main problem remains the same - the price of petro-plastics is still lower than that of bioplastics. Despite this, the biggest companies of the world are starting an initiative to manufacture this new kind of plastics and to widen the range of bioplastics usage in packaging. Considering today’s situation and tendencies, at the end of this paper the recommendations for the improvement and speeding up of the processes related to bioplastics manufacture, usage and its waste management in Europe and Lithuania are presented. DOI: http://dx.doi.org/10.5755/j01.erem.68.2.6777

  15. One Antimatter— Two Possible Thermodynamics

    Directory of Open Access Journals (Sweden)

    Alexander Y. Klimenko

    2014-02-01

    Full Text Available Conventional thermodynamics, which is formulated for our world populated by radiation and matter, can be extended to describe physical properties of antimatter in two mutually exclusive ways: CP-invariant or CPT-invariant. Here we refer to invariance of physical laws under charge (C, parity (P and time reversal (T transformations. While in quantum field theory CPT invariance is a theorem confirmed by experiments, the symmetry principles applied to macroscopic phenomena or to the whole of the Universe represent only hypotheses. Since both versions of thermodynamics are different only in their treatment of antimatter, but are the same in describing our world dominated by matter, making a clear experimentally justified choice between CP invariance and CPT invariance in context of thermodynamics is not possible at present. This work investigates the comparative properties of the CP- and CPT-invariant extensions of thermodynamics (focusing on the latter, which is less conventional than the former and examines conditions under which these extensions can be experimentally tested.

  16. Is JPC = 3-+ molecule possible?

    Science.gov (United States)

    Zhu, Wei; Liu, Yan-Rui; Yao, Tao

    2015-02-01

    The confirmation of charged charmonium-like states indicates that heavy quark molecules should exist. Here we discuss the possibility of a molecule state with JPC = 3-+. In a one-boson-exchange model investigation for the S wave C = + D*D¯2* states, one finds that the strongest attraction is in the case J = 3 and I = 0 for both π and σ exchanges. Numerical analysis indicates that this hadronic bound state might exist if a phenomenological cutoff parameter around 2.3 GeV (1.5 GeV) is reasonable with a dipole (monopole) type form factor in the one-pion-exchange model. The cutoff for binding solutions may be reduced to a smaller value once the σ exchange contribution is included. If a state around the D*D¯2* threshold (≈4472 MeV) in the channel J/ψω (P wave) is observed, the heavy quark spin symmetry implies that it is not a cc¯ meson and the JPC are likely to be 3-+. Supported by National Natural Science Foundation of China (11275115), Shandong Province Natural Science Foundation (ZR2010AM023), SRF for ROCS, SEM, and Independent Innovation Foundation of Shandong University

  17. Human resources and their possible forensic meanings.

    Science.gov (United States)

    Russo, Andrea; Urlić, Ivan; Kasum, Josip

    2015-09-01

    Forensics (forensic--before the Forum) means the application of knowledge from different scientific fields in order to define facts in judicial and/or administrative procedures. Nowadays forensics, besides this, finds its application even in different economic processes. For example, forensics enters the commercial areas of business intelligence and of different security areas. The European Commission recognized the importance of forensics, and underscored the importance of development of its scientific infrastructure in member States. We are witnessing the rise of various tragedies in economic and other kinds of processes. Undoubtedly, the world is increasingly exposed to various forms of threats whose occurrences regularly involve people. In this paper we are proposing the development of a new approach in the forensic assessment of the state of human resources. We are suggesting that in the focus should be the forensic approach in the psychological assessment of awareness of the individual and of the critical infrastructure sector operator (CISO) in determining the level of actual practical, rather than formal knowledge of an individual in a particular field of expertise, or in a specific scientific field, and possible forensic meanings.

  18. Pseudomonas biofilms: possibilities of their control.

    Science.gov (United States)

    Masák, Jan; Čejková, Alena; Schreiberová, Olga; Rezanka, Tomáš

    2014-07-01

    Genus Pseudomonas includes a large number of species that can be encountered in biotechnological processes as well as in the role of serious human or plant pathogens. Pseudomonads easily form biofilms on various types of surfaces. The biofilm phenotype is characterized by an increased resistance to environmental influences including resistance to antibiotics and other disinfectants, causing a number of problems in health care, food industry, and other areas. Considerable attention is therefore paid to the possibilities of eradication/destruction of pseudomonads biofilms both in terms of understanding the mechanisms of biofilm formation and at the level of finding suitable antibiofilm tools applicable in practice. The first part of this review is devoted to an overview of the regulatory mechanisms that are directly or indirectly involved in the formation of biofilm. The most effective approaches to suppressing the formation of biofilm that do not cause the development of resistance are based on the application of substances that interfere with the regulatory molecules or block the appropriate regulatory mechanisms involved in biofilm development by the cells. Pseudomonads biofilm formation is, similar to other microorganisms, a sophisticated process with many regulatory elements. The suppression of this process therefore also requires multiple antibiofilm tools.

  19. Lunar resources: possibilities for utilization

    Science.gov (United States)

    Shevchenko, Vladislav

    Introduction: With the current advanced orbiters sent to the Moon by the United States, Europe, Japan, China, and India, we are opening a new era of lunar studies. The International Academy of Aeronautics (IAA) has begun a study on opportunities and challenges of developing and using space mineral resources (SRM). This study will be the first international interdisciplinary assessment of the technology, economics and legal aspects of using space mineral resources for the benefit of humanity. The IAA has approved a broad outline of areas that the study will cover including type, location and extent of space mineral resources on the Moon, asteroids and others. It will be studied current technical state of the art in the identification, recovery and use of SRM in space and on the Earth that identifies all required technical processes and systems, and that makes recommendations for specific technology developments that should be addressed near term at the system and subsystem level to make possible prospecting, mineral extraction, beneficiation, transport, delivery and use of SMR. Particular attention will be dedicated to study the transportation and retrieval options available for SRM. Lunar polar volatile: ROSCOSMOS places a high priority on studying lunar polar volatiles, and has outlined a few goals related to the study of such volatiles. Over the course of several years, NASA’s Lunar Reconnaissance Orbiter scanned the Moon’s South Pole using its Lunar Exploration Neutron Detector (LEND - IKI Russia) to measure how much hydrogen is trapped within the lunar soil. Areas exhibiting suppressed neutron activity indicate where hydrogen atoms are concentrated most, strongly suggesting the presence of water molecules. Current survey of the Moon’s polar regions integrated geospatial data for topography, temperature, and hydrogen abundances from Lunar Reconnaissance Orbiter, Chandrayaan-1, and Lunar Prospector to identify several landing sites near both the North and

  20. Bioenergy possibilities in Northwest Russia

    Energy Technology Data Exchange (ETDEWEB)

    Rakitova, O. (The National Bioenergy Union, Saint Petersburg (Russian Federation)); Mutanen, K. (Joensuu Regional Development Company JOSEK Ltd, Joensuu (Finland))

    2007-07-01

    energy use. Biomass potential in N W Russia can be compared to present use and potential in Finland. Finland produces 7 times more energy from wood than N W Russia. Compared to Finland potential to increase wood energy is 10 20 times more compared to the present use in N W Russia. The potential to use wastes from agriculture, municipal waste and biogas is remarkable, also. In order to realize this potential Northwest Russia has set a goal to increase use of bioenergy up to 16 % of all energy in 2020. Growth in utilization of wood energy is strongly connected to new investments in mechanical and chemical forest industry. There are already over 30 pellet manufacturing plants in N W Russia that have total capacity to produce over 500000 tonnes pellets annually. Major part of the production is exported but local use is starting as well. Although the peat reserves of N W Russia are huge the possibilities to increase production for energy are limited due to poor infrastructure and lack of operators, skilled workforce and lack of local users. The region suffers still from ecological, social and economical problems. Large scale utilization of biomass for energy could offer a partial solution to these problems. Russia has signed the Kyoto Protocol, will very probably join WTO and has decided to set heavy customs on exported raw wood. These issues are important in promotion of new investments in the bioenergy sector as well. (orig.)

  1. ANALYSIS OF POSSIBLE BLOCK SCHEMATIC DIAGRAMS OF ELECTROMECHANICAL TRANSMISSIONS FOR WHEEL TRACTORS

    Directory of Open Access Journals (Sweden)

    A. Kliuchnikov

    2012-01-01

    Full Text Available The paper considers advantages of stepless electromechanical transmissions. Possible diagrams of their development for application at wheel tractors have been presented in the paper. schemes for wheel tractors applications Presented and analyzed. 

  2. [Possibility of using DST-30 thermoelastoplast in blood transfusion systems].

    Science.gov (United States)

    Il'iakov, E V; El'tsefon, B S; Polezhaev, V V; Zotkina, I V; Krivonosov, A I

    1979-01-01

    Investigating possible application of the DCT-30 thermoelastoplastic shows advantages of some physico-technical properties of this product based on natural caoutchouc and latex by comparison with base-rubber onene. It justifies recommending the former for making injection tubes in the blood transfusion systems.

  3. Some possible astrophysical aplications of diamond anvil cells

    CERN Document Server

    Celebonovic, V

    1993-01-01

    This is a short review of the methodology of static high pressure exeperiments in diamond anvil cells,and some of their possible applications an astrophysics.As the paper was originally published in 1993.,an addendum hints at some of the recent developements in the field.

  4. Possibility of turbulence from a post-Navier-Stokes equation

    Energy Technology Data Exchange (ETDEWEB)

    Getreuer, Pascal [Mathematics Department, University of California, Los Angeles, Los Angeles, CA 90095 (United States); Albano, A.M. [Department of Physics, Bryn Mawr College, Bryn Mawr, PA 19010 (United States)]. E-mail: aalbano@brynmawr.edu; Muriel, A. [Data Transport Systems, 347 East 62nd street, New York, NY 10021 (United States)

    2007-06-18

    We introduce corrections to the Navier-Stokes equation arising from the transitions between molecular states and the injection of external energy. In the simplest application of the proposed post-Navier-Stokes equation, we find a multi-valued velocity field and the immediate possibility of velocity reversal, both features of turbulence.

  5. Possibility of Turbulence from a Post-Navier-Stokes Equation

    CERN Document Server

    Getreuer, P; Muriel, A; Getreuer, Pascal

    2006-01-01

    We introduce corrections to the Navier-Stokes equation arising from the transitions between molecular states and the injection of external energy. In the simplest application of the proposed post Navier-Stokes equation, we find a multi-valued velocity field and the immediate possibility of velocity reversal, both features of turbulence.

  6. Estimations of expectedness and potential surprise in possibility theory

    Science.gov (United States)

    Prade, Henri; Yager, Ronald R.

    1992-01-01

    This note investigates how various ideas of 'expectedness' can be captured in the framework of possibility theory. Particularly, we are interested in trying to introduce estimates of the kind of lack of surprise expressed by people when saying 'I would not be surprised that...' before an event takes place, or by saying 'I knew it' after its realization. In possibility theory, a possibility distribution is supposed to model the relative levels of mutually exclusive alternatives in a set, or equivalently, the alternatives are assumed to be rank-ordered according to their level of possibility to take place. Four basic set-functions associated with a possibility distribution, including standard possibility and necessity measures, are discussed from the point of view of what they estimate when applied to potential events. Extensions of these estimates based on the notions of Q-projection or OWA operators are proposed when only significant parts of the possibility distribution are retained in the evaluation. The case of partially-known possibility distributions is also considered. Some potential applications are outlined.

  7. Transportation optimization with fuzzy trapezoidal numbers based on possibility theory.

    Science.gov (United States)

    He, Dayi; Li, Ran; Huang, Qi; Lei, Ping

    2014-01-01

    In this paper, a parametric method is introduced to solve fuzzy transportation problem. Considering that parameters of transportation problem have uncertainties, this paper develops a generalized fuzzy transportation problem with fuzzy supply, demand and cost. For simplicity, these parameters are assumed to be fuzzy trapezoidal numbers. Based on possibility theory and consistent with decision-makers' subjectiveness and practical requirements, the fuzzy transportation problem is transformed to a crisp linear transportation problem by defuzzifying fuzzy constraints and objectives with application of fractile and modality approach. Finally, a numerical example is provided to exemplify the application of fuzzy transportation programming and to verify the validity of the proposed methods.

  8. Possibilities for reuse of treated domestic wastewater in the Netherlands.

    Science.gov (United States)

    Rietveld, L C; Norton-Brandão, D; Shang, R; van Agtmaal, J; van Lier, J B

    2011-01-01

    The implementation of wastewater reuse is becoming an increasingly important means of supplementing water supply needs and/or reducing costs. The present paper provides examples of possible uses of treated domestic effluent for the three sectors, i.e. public water supply, industrial and agricultural uses with the aim to address the feasibility of these applications. It is concluded that, although The Netherlands as a whole is considered to be a low water stressed country, regional fresh water scarcity and costs can result in the need for applications of domestic wastewater reuse.

  9. Perspectives on clinical possibility: elements of analysis.

    Science.gov (United States)

    Chiffi, Daniele; Zanotti, Renzo

    2016-08-01

    Possibility is one of the most common modalities in reasoning and argumentation. Various kinds of modal concepts have been identified in philosophical and logical discussion of the metaphysics of modality. We focus here on the concept of clinical possibility. A critical analysis of what is intended as clinical possibility has not yet received sufficient examination, although the concept is extensively used in clinical reasoning. We present arguments to emphasize some desirable features associated with the concept of clinical possibility. We argue that almost all clinical possibilities are potentialities, that is, possibilities that may be actualized by effective, appropriate and feasible interventions. However, in some limited cases, even mere possibilities - which may or may not be actualized, since we do not have the required knowledge - may be involved in clinical reasoning, and we present some examples in this paper. We then introduce some basic views on the nature of possibility showing their validity and limitations when applied to the concept of clinical possibility. Lastly, we conjecture that clinical possibility is a normative modality that can be formalized in a multimodal system with epistemic and deontic logical operators.

  10. POSSIBILITIES FOR OPTIMIZATION OF CIRCUIT ACCELERATING OPERATION OF ELECTROMAGNETS

    Directory of Open Access Journals (Sweden)

    S. S. Stoyanova

    2005-01-01

    Full Text Available The paper reveals an accelerating circuit for electromagnet operation with the help of an additional resistor R that is shunted with a capacitor C. Resistor R is connected in series with the electromagnet winding. The possibility of the circuit optimization has been substantiated with the purpose to limit the final speed with which a movable part of the electromagnet reaches a limiter. Such circuit may find its application in relay protection.

  11. Possibilities of energy recovery and integrated energy supply for foundries

    Science.gov (United States)

    Pautz, J.

    1980-08-01

    The energy utilization of foundries equipped with electric melting and arc furnaces was investigated. Systems were studied which optimize heat economy. Studies of the energy balance of arc furnaces with conventional refractory linings and with water cooled linings clearly demonstrate recovery possibilities as a function of the temperature of the waste heat. Domestic water heating, central heating, scrap drying and steam generator plant applications are proposed for the recovered heat. A considerable overall improvement in efficiency can be achieved.

  12. STEREOLOGY FROM ONE OF ALL THE POSSIBLE ANGLES

    Directory of Open Access Journals (Sweden)

    Leszek Wojnar

    2011-05-01

    Full Text Available Relation between image analysis and stereology is discussed in terms of different fields of applications, especially materials science, biology and medicine. Some long-term tendencies observed as well as possible future trends are discussed. The need of a wider use of image analysis techniques including ma1hematical morphology in any field of science is demons1rated. Simultaneously, the significance of stereological background in automatic quantification of1he investigated structures is confirmed.

  13. Possibilities of Using Several Discrete Transforms for the Video Compression

    Directory of Open Access Journals (Sweden)

    I. Chromy

    2000-04-01

    Full Text Available This paper treats of compression of digital video signals and the mainaim is to probe the possibility of using several discrete transformsbesides well-known discrete cosine transform (DCT. Mathematicaldescription of these transforms is presented in the article. DCT andother orthogonal transforms are described here. Matrix notation ofcomputation of two-dimensional transform is also presented. Thecomparison of the results obtained by application of the transforms onpictures is introduced.

  14. Squalane as a possible carrier of bone morphogenetic protein.

    Science.gov (United States)

    Kawakami, T; Uji, H; Antoh, M; Hasegawa, H; Kise, T; Eda, S

    1993-07-01

    Gelatin capsules containing squalane partially purified bone morphogenetic protein (BMP) complex were placed on the perimuscular membrane of rats. Two kinds of control, gelatin capsules containing only BMP and those bearing squalane only, were used. The embedded areas were histopathologically examined at 3 and 6 wk after the operation. The observations revealed that the squalane/BMP complex elicited wide heterotopic bone formation with bone marrow tissue, suggesting that squalane is a possible carrier of BMP for clinical applications.

  15. POSSIBILITY AND EVIDENCE-BASED RELIABILITY ANALYSIS AND DESIGN OPTIMIZATION

    Directory of Open Access Journals (Sweden)

    Hong-Zhong Huang

    2013-01-01

    Full Text Available Engineering design under uncertainty has gained considerable attention in recent years. A great multitude of new design optimization methodologies and reliability analysis approaches are put forth with the aim of accommodating various uncertainties. Uncertainties in practical engineering applications are commonly classified into two categories, i.e., aleatory uncertainty and epistemic uncertainty. Aleatory uncertainty arises because of unpredictable variation in the performance and processes of systems, it is irreducible even adding more data or knowledge. On the other hand, epistemic uncertainty stems from lack of knowledge of the system due to limited data, measurement limitations, or simplified approximations in modeling system behavior and it can be reduced by obtaining more data or knowledge. More specifically, aleatory uncertainty is naturally represented by a statistical distribution and its associated parameters can be characterized by sufficient data. If, however, the data is limited and can be quantified in a statistical sense, epistemic uncertainty can be considered as an alternative tool in such a situation. Of the several optional treatments for epistemic uncertainty, possibility theory and evidence theory have proved to be the most computationally efficient and stable for reliability analysis and engineering design optimization. This study first attempts to provide a better understanding of uncertainty in engineering design by giving a comprehensive overview of its classifications, theories and design considerations. Then a review is conducted of general topics such as the foundations and applications of possibility theory and evidence theory. This overview includes the most recent results from theoretical research, computational developments and performance improvement of possibility theory and evidence theory with an emphasis on revealing the capability and characteristics of quantifying uncertainty from different perspectives

  16. Making Space Travel to Jupiter Possible

    Science.gov (United States)

    Barker, Samuel P.

    2004-01-01

    From man landing on the moon to a simple satellite being launched into orbit, many incredible space accomplishments have been witnessed by us all. However, what goes un-noticed to the common man is the extensive research and testing that lasts months, years, and even decades. Much of this required research just so happens to take place in the corridors of the Glen Research Center building number 49. In the Advanced Materials division of G.R.C., a number of researchers have the responsibility of discovering which metal, ceramic, or polymer is best for a specific application. Under the guidance of mentor extraordinaire Frank Ritzert, I am involved in many critical projects dealing with refractory metals, two of which I will mention in this report. The Jupiter Icy Moons Orbiter (JIMO) project actually was under full swing back in the 50's and early 60's. To enable the 14 year trek to the icy moons of Europa, Callisto, and Ganymede, nuclear propulsion methods were selected. Due to the extreme temperature of the reactor and the extended time period, a refractory metal would need to be implemented. After years of research and progress, the program was suddenly canceled. About a decade ago, the JIMO project was re-instated and now has a goal for departure around 2014. However, a few obstacles lie in our way concerning the use of refractory metals. In certain areas of the orbiter a joint is required between the refractories and other less dense metals. Two of these joints are with nickel based super alloys. Being an intern for Frank Ritzert, the refractory metals expert, I have the opportunity to develop the best method to braze refractory metals to Nickel 201. This involves the actual brazing, electron microscopy and reporting the results. My second project involves a certain part of the orbiter where Niobium 1Zirconium, a refractory metal, is joined with Hastelloy-X a Ni based metal. Small quantities of oxygen, helium and other impurities in the Ni alloy could diffuse

  17. Duloxetine and suicide attempts: a possible relation

    Directory of Open Access Journals (Sweden)

    Salem Bilal A

    2008-06-01

    Full Text Available Abstract The possible increase of suicidal ideation with some antidepressants is still a matter of debate. We are reporting two cases of suicidal attempt that occurred concomitantly with the use of Duloxetine. To our knowledge there is no prior publication about a possible Duloxetine related increase in the risk of suicidality.

  18. Possible pathogenetic types of sporadical ovarian cancer

    Directory of Open Access Journals (Sweden)

    L. A. Ashrafyan

    2012-01-01

    Full Text Available This article in question dwells on a possible pathogenetic model ovarian cancer, it’s histogenesis speciality, the role of ovulation, chronic in- flammation and stem cells. The scheme of two variant of avarian cancer progress and possible ways of prevention it are represented as well.

  19. Transcription of Byzantine Chant - Problems, Possibilities, Formats

    DEFF Research Database (Denmark)

    Troelsgård, Christian

    2007-01-01

    Discusses the problems and possibilities for transsription of Byzantine chant on the basis of medieval musical manuscripts. A relatively 'neutral' style of transcription is suggested for musicological purposes.......Discusses the problems and possibilities for transsription of Byzantine chant on the basis of medieval musical manuscripts. A relatively 'neutral' style of transcription is suggested for musicological purposes....

  20. Pitfalls and possibilities of radar compressive sensing.

    Science.gov (United States)

    Goodman, Nathan A; Potter, Lee C

    2015-03-10

    In this paper, we consider the application of compressive sensing (CS) to radar remote sensing applications. We survey a suite of practical system-level issues related to the compression of radar measurements, and we advocate the consideration of these issues by researchers exploring potential gains of CS in radar applications. We also give abbreviated examples of decades-old radio-frequency (RF) practices that already embody elements of CS for relevant applications. In addition to the cautionary implications of system-level issues and historical precedents, we identify several promising results that RF practitioners may gain from the recent explosion of CS literature.

  1. Bone Marrow Transplants: "Another Possibility at Life"

    Science.gov (United States)

    ... page please turn Javascript on. Feature: Bone Marrow Transplants “Another Possibility at Life” Past Issues / Summer 2011 ... for 16,000 of them, a bone marrow transplant is the best treatment option, notes Susan F. ...

  2. The CLO 3.0.9 an ETOM based in risk by unavailability of barriers and it possible application in the CNLV; La CLO 3.0.9 una ETOM basada en riesgo por indisponibilidad de barreras y su eventual aplicacion en la CNLV

    Energy Technology Data Exchange (ETDEWEB)

    Arredondo S, C. [ININ, 52750 Ocoyoacac, Estado de Mexico (Mexico)]. e-mail: cas@nuclear.inin.mx

    2007-07-01

    Presently work a Technical Specification of Improved Operation (ETOM) based on risk, proposal and already adopted by some nuclear power stations in the USA is analyzed. This ETOM is the CLO 3.0.9 Operation Limit Condition, concerning to unavailability of barriers, the corresponding analysis that includes deterministic and probabilistic considerations and it is superficially discussed their eventual application to the Laguna Verde Nucleo electric Central (CNLV). The impact in the risk of the proposed changes to the Operation Technical Specification (ETO) it was evaluated following a treatment of three roads recommended by the regulatory guide RG 1.177. It consisted of a simplified analysis of demarcation of the consequent risk with the lack of specific models of risk for this case on each power station, which don't include models of flaw of such passive structures as they are these barriers. Together with the results of the risk evaluation, it is also evaluated the impact on the defense in depth of adding the CLO 3.0.9 proposal to the ETO. With base in the integrated evaluation it was concluded that the change proposed to ETO carries insignificant increases of risk. Certainly, this conclusion is certain without considering any credit for the removal of undesirable potential consequences associated with the current conservative treatment of barriers. With the purpose of to identify and to justify the late times to enter to the actions corresponding to the supported equipment associated with the unavailable barriers, it was presented a change proposal with an analysis informed in risk using Probabilistic Risk Analysis methods (APR), combined with deterministic arguments and of defense in depth. The proposal of the licensees includes the NEI 04-08 guide providing detailed guide on the evaluation and handling of risk associated with the unavailability barriers, the above mentioned according to the 1.174 and 1.177 Regulatory guides. The evaluation procedure of the

  3. Possible mechanism of adhesion in a mica supported phospholipid bilayer

    Energy Technology Data Exchange (ETDEWEB)

    Pertsin, Alexander, E-mail: ig3@ix.urz.uni-heidelberg.de [Angewandte Physikalische Chemie, Universität Heidelberg, Im Neuenheimer Feld 253, 69120 Heidelberg (Germany); Institute of Organo-Element Compounds, Russian Academy of Sciences, Vavilov Str. 28, 117991 Moscow (Russian Federation); Grunze, Michael [Angewandte Physikalische Chemie, Universität Heidelberg, Im Neuenheimer Feld 253, 69120 Heidelberg (Germany); Institute for Functional Interfaces, Karlsruhe Institute of Technology, Hermann-von- Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen (Germany)

    2014-05-14

    Phospholipid bilayers supported on hydrophilic solids like silica and mica play a substantial role in fundamental studies and technological applications of phospholipid membranes. In both cases the molecular mechanism of adhesion between the bilayer and the support is of primary interest. Since the possibilities of experimental methods in this specific area are rather limited, the methods of computer simulation acquire great importance. In this paper we use the grand canonical Monte Carlo technique and an atomistic force field to simulate the behavior of a mica supported phospholipid bilayer in pure water as a function of the distance between the bilayer and the support. The simulation reveals a possible adhesion mechanism, where the adhesion is due to individual lipid molecules that protrude from the bilayer and form widely spaced links with the support. Simultaneously, the bilayer remains separated from the bilayer by a thin water interlayer which maintains the bilayer fluidity.

  4. Carbon nanoparticles as possible radioprotectors in biological systems

    Science.gov (United States)

    Krokosz, Anita; Lichota, Anna; Nowak, Katarzyna E.; Grebowski, Jacek

    2016-11-01

    Ionizing radiation causes radiolysis of water and the production of reactive oxygen species (ROS), which interact with biochemically important molecules in cells leading to cell death. In order to reduce the dangerous radiation effects on cells, tissues and organs, the search for radioprotectors is essential. ROS result in damage to biomolecules, e.g. proteins, lipids and DNA, and as a consequence, cause the loss of cell function. The chemical and biological properties of fullerenes and other carbon nanoparticles enable the possibility of generating either oxidative stress or its attenuation by both scavenging free radicals and modification/upregulation of endogenous antioxidative systems in cells. This study discusses the possible applications of carbon nanoparticles as radioprotective agents and/or free radical scavengers. Special attention is paid to water-soluble fullerenes as they are promising radioprotectors and exhibit low toxicity and cytotoxicity.

  5. Silkworm protein: its possibility as an actuator

    Science.gov (United States)

    Jin, Hyoung-Joon; Myung, Seung Jun; Kim, Heung Soo; Jung, Woochul; Kim, Jaehwan

    2006-03-01

    The possibility of silkworm (Bombyx mori) protein as a base material of biomimetic actuator was investigated in this paper. Silkworm films were prepared from high concentrations of regenerated fibroin in aqueous solution. Films with thickness of about 100 μm were prepared for coating electrodes. The cast silk films were coated by very thin gold electrode on both sides of the film. Tensile test of cast film showed bi-modal trend, which is typical stress-strain relation of polymeric film. As the test of a possible biomimetic actuator, silkworm film actuator provides bending deformations according to the magnitude and frequency of the applied electric filed. Although the present bending deformation of silkworm film actuator is smaller than that of Electro-Active Paper actuator, it provides the possibility of biomimetic actuator.

  6. Adenosine triphosphate (ATP) as a possible indicator of extraterrestrial biology

    Science.gov (United States)

    Chappelle, E. W.; Picciolo, G. L.

    1974-01-01

    The ubiquity of adenosine triphosphate (ATP) in terrestrial organisms provides the basis for proposing the assay of this vital metabolic intermediate for detecting extraterrestrial biological activity. If an organic carbon chemistry is present on the planets, the occurrence of ATP is possible either from biosynthetic or purely chemical reactions. However, ATP's relative complexity minimizes the probability of abiogenic synthesis. A sensitive technique for the quantitative detection of ATP was developed using the firefly bioluminescent reaction. The procedure was used successfully for the determination of the ATP content of soil and bacteria. This technique is also being investigated from the standpoint of its application in clinical medicine.

  7. [Meta-cognitive strategies: a possibility in nursing education].

    Science.gov (United States)

    Almeida, Miriam de Abreu

    2002-01-01

    This article is a theoretical reflection about the possibility of the application of metacognition strategies in nursing education. Metacognition is a reflective attitude of self-awareness and control of the mental processes. The metacognition area of cognitive psychology is analyzed, focusing on the problem solving process. The importance of metacognition in education is approached with emphasis on the teacher's role as a mediator in the student's learning process, in which "learning to learn" is emphasized. Some examples of its use in different situations of nursing education such as in text reading and nursing process, are reported.

  8. Megalithic Monument of Abuli, Georgia, and Possible Astronomical Signi cance

    Science.gov (United States)

    Jijelava, Badri; Simonia, Irakli

    2016-08-01

    Background/Objectives: In recent years, in purpose of investigation of the artefacts, the ancient culture and religion, based on the astronomy knowledge play significant role. The aim of this work is to identify the orientations of the religious megalithic complexes and their correlation to the celestial luminaries. Methods/Statistical Analysis: We harmonized the archeological data, ethnographical, historical information and restoration of ancient celestial sphere (using special astronomy application), which give us possibility to identify the correlations between the acronychal or helical rising/ set of luminaries and directions of megalithic objects. Very often such connections are stored in a current folklore too. Findings: This technique of investigations give us more clear understanding of ancient universe. Using this method, we can receive latent information about the ancient Gods - Luminaries, clarify current mythology, date of the megalithic complex. Application/Improvements: This method of investigation is an additional instrument for archeological investigations,

  9. Possible use of fuzzy logic in database

    Directory of Open Access Journals (Sweden)

    Vaclav Bezdek

    2011-04-01

    Full Text Available The article deals with fuzzy logic and its possible use in database systems. At first fuzzy thinking style is shown on a simple example. Next the advantages of the fuzzy approach to database searching are considered on the database of used cars in the Czech Republic.

  10. Energy source possibilities in underwater technics

    Science.gov (United States)

    Farin, Juho

    1991-04-01

    Underwater energy source possibilities are treated. The power demand of underwater vehicles is restricted to approximately 0.5 MW. Besides well known primary and secondary batteries as well as conventional diesel engines and closed cycle diesels, fuel cells, radio nuclear isotopes and small nuclear reactors have already been installed or tested in conditions representative of underwater.

  11. Other Possible Heart Disease Risk Factors

    Science.gov (United States)

    ... Heart Health and Stroke Other possible heart disease risk factors Related information Depression fact sheet Stress and your health fact sheet ... Research also suggests that depression itself is a risk factor for heart disease. Depression, stress, and other negative emotions may affect the ...

  12. Teachers Avoiding Learners' Avoidance: Is It Possible?

    Science.gov (United States)

    Tadayyon, Maedeh; Zarrinabadi, Nourollah; Ketabi, Saeed

    2016-01-01

    Dealing with learners who prefer to take the back seat and avoid classroom participation can be every teacher's nightmare. This lack of participation may cause teacher frustration, and possibly the only way to reduce this lack of participation is to access the concept of avoidance strategy. Avoidance strategy is the abandonment of a classroom task…

  13. The Possibilities of Postcolonial Praxis in Education

    Science.gov (United States)

    Subedi, Binaya; Daza, Stephanie Lynn

    2008-01-01

    This introduction to the special issue explores the possibilities of postcolonial praxis in the field of education. The local/global focus of postcolonial perspectives invites alternative ways of theorizing question of pedagogy, curriculum and research. Postcolonial praxis similarly highlights how questions of differences and identity need to be…

  14. Revisiting the Regenerative Possibilities of Ortiz

    Science.gov (United States)

    Duques, Matthew

    2004-01-01

    The author of this article revisits Simon Ortiz's poem, "From Sand Creek," in which the latter can in so few words convey both the horrific tragedy of conquest and colonization, while at the same time find a space for possibility, a means for recovery that is never about forgetting but always occurs as a kind of recuperative remembering. Ortiz…

  15. Our Visions of Possibility for Literacy

    Science.gov (United States)

    O'Keefe, Tim; Reinier, Rise; Gallagher, Kevin; Morgan, Bruce; Lopez-Robertson, Julia; Santman, Donna; Wong-Kam, JoAnn; Hill, Sharon; Christensen, Linda

    2006-01-01

    Tim O'Keefe, Rise Reinier and Kevin Gallagher, Bruce Morgan, Julia Lopez-Robertson, Donna Santman, JoAnn Wong-Kam, Sharon Hill, and Linda Christensen provide short essays describing their personal visions of possibility about literacy and how they maintain that passion and vision. Across a range of contexts, they reflect on the ways in which their…

  16. A possible link between food and mood

    DEFF Research Database (Denmark)

    Jørgensen, Bettina Merete Pyndt; Hansen, Julie Torpe; Krych, Lukasz;

    2014-01-01

    behavioral symptoms which can be interpreted as depression-like, and the possible influence of the gut microbiota (GM) in this. Fourty-two mice were randomly assigned to one of three experimental diets, a high-fat, a high-sucrose or a control diet for thirteen weeks. Mice on high-fat diet gained more weight...

  17. Autism Biomarkers: Challenges, Pitfalls and Possibilities

    Science.gov (United States)

    Anderson, George M.

    2015-01-01

    Network perspectives, in their emphasis on components and their interactions, might afford the best approach to the complexities of the ASD realm. Categorical approaches are unlikely to be fruitful as one should not expect to find a single or even predominant underlying cause of autism behavior across individuals. It is possible that the complex,…

  18. On Measuring Technological Possibilities by Hypervolumes

    DEFF Research Database (Denmark)

    Asmild, Mette; Hougaard, Jens Leth

    2016-01-01

    Measuring technological possibilities is a somewhat neglected topic in the productivity analysis literature. We discuss existing methods as well as an obvious alternative measure based on hypervolumes. We illustrate the use of a volume-based measure on an empirical case of demolition projects from...

  19. Imagination "First": Unleash the Power of Possibility

    Science.gov (United States)

    Handa, Manoj Chandra

    2015-01-01

    The creativity program, "imagination 'first': unleash the power of possibility," implemented in public primary and secondary schools in Northern Sydney, New South Wales, Australia, deals with the power of imagination in unleashing creativity among gifted students and teachers. Following an in-depth literature review on creativity for…

  20. Possibilities for focusing ultrasonic fields - A survey

    Science.gov (United States)

    Schlengermann, U.

    1986-05-01

    Focusing techniques for ultrasound devices used in NDE are examined in a review of recent experimental investigations and application reports. The advantages of focused sound fields are outlined (including increased sensitivity, lateral resolution, and S/N and improved reflector scanning); the characteristics of the focused field are reviewed; the fundamental principles of curved-crystal, lens, curved-reflector, zone-plate, and phase-plate focusing are explained; and their practical adaptation in NDE problems (by changing delay path, changing lenses, or switching annular arrays) is described. Consideration is given to geometric and technical limitations on focusing applicability and to the optimization of focusing. Diagrams and drawings are provided.

  1. AD/HD: POSSIBLE DIAGNOSIS AND TREATMENT

    Directory of Open Access Journals (Sweden)

    Karl REICHELT

    2008-12-01

    Full Text Available The purpose of this paper is to show that a more exact diagnosis and dietary intervention in AD/HD (Attention Deficit/Hyperactivity Di­sor­der is possible and probable. The clinical symptom based diagnosis we suggest may be supplemented with physiological tests. A ge­netic and environmental inter-action is clearly involved and explainable using phenyl­ke­tonuria as a model.Method: Examining peer reviewed published papers on gut to blood, blood to brain inter­action and effect of interventions in AD/HD and our own studies in the field. The various treatment options are discussed.Results: It can be shown that a gut to brain activity is possible and probable, and dietary intervention is useful and probably safer than drugs. Preliminary data on a small five year follow up of dietary intervention is shown.

  2. The simplest possible bouncing quantum cosmological model

    Science.gov (United States)

    Peter, Patrick; Vitenti, Sandro D. P.

    2016-06-01

    We present and expand the simplest possible quantum cosmological bouncing model already discussed in previous works: the trajectory formulation of quantum mechanics applied to cosmology (through the Wheeler-De Witt equation) in the Friedmann-Lemaître-Robertson-Walker (FLRW) minisuperspace without spatial curvature. The initial conditions that were previously assumed were such that the wave function would not change its functional form but instead provide a dynamics to its parameters. Here, we consider a more general situation, in practice consisting of modified Gaussian wave functions, aiming at obtaining a nonsingular bounce from a contracting phase. Whereas previous works consistently obtain very symmetric bounces, we find that it is possible to produce highly non-symmetric solutions, and even cases for which multiple bounces naturally occur. We also introduce a means of treating the shear in this category of models by quantizing in the Bianchi I minisuperspace.

  3. Possible alendronate-induced polyarticular synovitis.

    Science.gov (United States)

    Gökkus, K; Yazicioglu, G; Sagtas, E; Uyan, A; Aydin, A T

    2016-01-01

    We present a case of polyarticular synovitis following alendronate treatment for osteoporosis. The patient had no evidence of rheumatoid arthritis, pyrophosphate arthropathy, or seronegative/seropositive arthritis. Our main aim in this study is to highlight the potential adverse effects of alendronate and to warn orthopedic surgeons about the possibility of such a side effect that might lead orthopedic surgeons to administer wrong and unnecessary treatments like arthrocentesis. The withdrawal of alendronate is found to be the treatment of choice. Alendronate should be considered as a possible cause of synovitis or polyarthritis in patients treated with this agent in the absence of any other pathology. An association between alendronate and synovitis has rarely been described in the literature. We present a patient who developed polyarticular synovitis after treatment with alendronate and responded to its withdrawal.

  4. Possible alendronate-induced polyarticular synovitis

    Directory of Open Access Journals (Sweden)

    K Gökkus

    2016-01-01

    The patient had no evidence of rheumatoid arthritis, pyrophosphate arthropathy, or seronegative/seropositive arthritis. Our main aim in this study is to highlight the potential adverse effects of alendronate and to warn orthopedic surgeons about the possibility of such a side effect that might lead orthopedic surgeons to administer wrong and unnecessary treatments like arthrocentesis. The withdrawal of alendronate is found to be the treatment of choice. Alendronate should be considered as a possible cause of synovitis or polyarthritis in patients treated with this agent in the absence of any other pathology. An association between alendronate and synovitis has rarely been described in the literature. We present a patient who developed polyarticular synovitis after treatment with alendronate and responded to its withdrawal.

  5. Is a coherence theory of understanding possible?

    Directory of Open Access Journals (Sweden)

    Victor Gijsbers

    2015-03-01

    Full Text Available Coherence is a measure of how much our beliefs hang together. Understanding is achieved when we see that something is not just a brute, isolated fact. This suggests that it might be possible to develop a coherence theory of understanding, which is what we attempt to do in this article using several formal measures of coherence. However, it turns out that a coherence theory runs into trouble with the asymmetry of understanding. We identify four difficulties and give suggestions for how they could be solved. These solutions all point away from coherence and towards a rather different notion, unification, which casts some (though not conclusive doubt on the possibility of a coherence theory of understanding.

  6. How is an absolute democracy possible?

    Directory of Open Access Journals (Sweden)

    Joanna Bednarek

    2011-01-01

    Full Text Available In the last part of the Empire trilogy, Commonwealth, Negri and Hardt ask about the possibility of the self-governance of the multitude. When answering, they argue that absolute democracy, understood as the political articulation of the multitude that does not entail its unification (construction of the people is possible. As Negri states, this way of thinking about political articulation is rooted in the tradition of democratic materialism and constitutes the alternative to the dominant current of modern political philosophy that identifies political power with sovereignty. The multitude organizes itself politically by means of the constitutive power, identical with the ontological creativity or productivity of the multitude. To state the problem of political organization means to state the problem of class composition: political democracy is at the same time economic democracy.

  7. A Revisit to Probability - Possibility Consistency Principles

    Directory of Open Access Journals (Sweden)

    Mamoni Dhar

    2013-03-01

    Full Text Available In this article, our main intention is to highlight the fact that the probable links between probability and possibility which were established by different authors at different point of time on the basis of some well known consistency principles cannot provide the desired result. That is why the paper discussed some prominent works for transformations between probability and possibility and finally aimed to suggest a new principle because none of the existing principles because none of them found the unique transformation. The new consistency principle which is suggested hereby would in turn replace all others that exist in the literature references by providing a reliable estimate of consistency between the two.Furthermore some properties of entropy of fuzzy numbers are also presented in this article.

  8. The simplest possible bouncing quantum cosmological model

    CERN Document Server

    Peter, Patrick

    2016-01-01

    We present and expand the simplest possible quantum cosmological model already discussed in a previous work: the trajectory formulation of quantum mechanics applied to cosmology in the FLRW minisuperspace without spatial curvature. The initial conditions that were assumed there were such that the wave function would not change its functional form but instead provide a dynamics to its parameters. Here, we consider a more general situation, in practice consisting of modified Gaussian wave functions, aiming at obtaining a bounce from a contracting phase. Whereas previous works consistently obtain very symmetric bounces, we find that it is possible to produce highly non symmetric solutions, and even cases for which multiple bounces naturally occur. We also introduce a means of treating the shear in this category of models by quantizing in the Bianchi I minisuperpace.

  9. Active infrared systems: possible roles in ballistic missile defense?

    Science.gov (United States)

    Paleologue, A.

    2006-05-01

    Active Infra-Red (IR) systems developed in the past ten years are now available for missile defense applications. The main purpose of this paper is to describe the advantages an active IR system could offer to a ballistic missile defense (BMD). The active IR system considered in this paper is a LIDAR (LIght Detection And Ranging) system. Historically, the Lincoln Laboratory in the USA began using lasers in the early 1960's. The initial applications included the development of a LIDAR system enabling the measurement of the distance between the earth and the moon in 1962. Satellite tracking using LIDAR began early in 1973. Today, technological developments, with the miniaturization of systems and increased performance levels, have enabled new ambitious projects such as the Discrimination Interceptor Technology Program (DITP) program started in 1998 and the use of LIDAR to help in the discrimination of future exo-atmospheric interceptors within the framework of BMD. The first part of this paper presents the possible contribution of LIDAR to BMD: the main roles, objectives, and strategic advantages. The second part gives a brief overview of the technological features of a generic LIDAR instrument, rapidly addressing laser sources, detectors, optics and electronics. Finally, a modeling of an IR LIDAR system, limited solely to direct detection, and an estimation of performance levels will be presented. A list of possible IR active discriminators will be then presented on the basis of the previous analysis and proposed as new constraints in the design of discrete objects.

  10. UAV PHOTOGRAMMETRY IMPLEMENTATION TO ENHANCE LAND SURVEYING, COMPARISONS AND POSSIBILITIES

    Directory of Open Access Journals (Sweden)

    R. El Meouche

    2016-10-01

    Full Text Available The use of Unmanned Aerial Vehicles (UAVs for surveying is now widespread and operational for several applications – quarry monitoring, archeological site surveys, forest management and 3D modeling for buildings, for instance. UAV is increasingly used by land surveyors especially for those kinds of projects. It is still ambiguous whether UAV can be applicable for smaller sites and property division. Therefore, the objective of this research is to extract a vectorized plan utilizing a UAV for a small site and investigate the possibility of an official land surveyor exploiting and certificating it. To do that, two plans were created, one using a UAV and another utilizing classical land surveyor instruments (Total Station. A comparison was conducted between the two plans to evaluate the accuracy of the UAV technique compared to the classical one. Moreover, other parameters were also considered such as execution time and the surface covered. The main problems associated with using a UAV are the level of precision and the visualization of the whole area. The results indicated that the precision is quite satisfactory with a maximum error of 1.0 cm on ground control points, and 4 cm for the rest of the model. On the other hand, the results showed that it is not possible to represent the whole area of interest utilizing a UAV, due to vegetation.

  11. UAV Photogrammetry Implementation to Enhance Land Surveying, Comparisons and Possibilities

    Science.gov (United States)

    El Meouche, R.; Hijazi, I.; Poncet, P. A.; Abunemeh, M.; Rezoug, M.

    2016-10-01

    The use of Unmanned Aerial Vehicles (UAVs) for surveying is now widespread and operational for several applications - quarry monitoring, archeological site surveys, forest management and 3D modeling for buildings, for instance. UAV is increasingly used by land surveyors especially for those kinds of projects. It is still ambiguous whether UAV can be applicable for smaller sites and property division. Therefore, the objective of this research is to extract a vectorized plan utilizing a UAV for a small site and investigate the possibility of an official land surveyor exploiting and certificating it. To do that, two plans were created, one using a UAV and another utilizing classical land surveyor instruments (Total Station). A comparison was conducted between the two plans to evaluate the accuracy of the UAV technique compared to the classical one. Moreover, other parameters were also considered such as execution time and the surface covered. The main problems associated with using a UAV are the level of precision and the visualization of the whole area. The results indicated that the precision is quite satisfactory with a maximum error of 1.0 cm on ground control points, and 4 cm for the rest of the model. On the other hand, the results showed that it is not possible to represent the whole area of interest utilizing a UAV, due to vegetation.

  12. On the Possibility to Construct Gravitational Eye

    Institute of Scientific and Technical Information of China (English)

    CHEN Ying-Tian

    2007-01-01

    The possibility of modifying a conventional Cavendish torsion pendulum into a half-armed pendulum oscillator to measure the horizontal gravitational acceleration is discussed. A new kind of gravitational detector, gravieye,as we named, can be made by a proper combination of such oscillators to "see" remote objects and to be used, e.g. to detect the movement of huge mass at a long distance.

  13. What kinds of traffic forecasts are possible?

    DEFF Research Database (Denmark)

    Næss, Petter; Strand, Arvid

    2012-01-01

    Based on metatheoretical considerations, this paper discusses which kinds of traffic forecasts are possible and which kinds are impossible to make with any reasonable degree of accuracy. It will be argued on ontological and epistemological grounds that it is inherently impossible to make exact pr...... calculations at the tactical level; while more traditional micro-simulations should be applied only at a detailed operational level....

  14. Human reproduction: possibilities and ethical borders.

    Directory of Open Access Journals (Sweden)

    Pr RenĂŠ Frydman

    2010-01-01

    Full Text Available Reproductive medicine is a new important field in all the countries. The possibilities are tremendous, therefore we have to decide if limits are necessary or should we consider that everything that have been initiated (as clone, gene transfer... can be apply in humans. That will be the challenge of a global ethical approach in each country with their culture, morality, guidelines or laws.

  15. NEW POSSIBILITIES BROUGHT ABOUT BY HYPERTEXT

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    This paper explores the new possibilities of the novel in the context of technologies of computer hypertext. One of the central argmnents of the paper is that the operational logic of the novel can be made to approximate that of a web of hypertext links. The author also argues that the hope of the renaissance of the novel Iies in the technologically enhanced speed of the traffic in models between smooth space and striated space.

  16. Australia, Give You Endless Possibilities as Imagination…

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    @@ It's a place where the light changes everything. From the friendly attitude of its people, to the breathtaking blue of its skies and glistening gold of its sandy beaches. A place unlike any other, with animals and scenery you'll find nowhere else on earth and an unmatched diversity of fiavours, scents and sights. It is Australia, where the possibilities are only as endless as your imagination.

  17. Australia, Give You Endless Possibilities as Imagination…

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

      It's a place where the light changes everything. From the friendly attitude of its people, to the breathtaking blue of its skies and glistening gold of its sandy beaches. A place unlike any other, with animals and scenery you'll find nowhere else on earth and an unmatched diversity of fiavours, scents and sights. It is Australia, where the possibilities are only as endless as your imagination.……

  18. A Possible Origin of Dark Energy

    Institute of Scientific and Technical Information of China (English)

    T. D. Lee

    2004-01-01

    @@ We discuss the possibility that the existence of dark energy may be due to the presence ofa spin zero field φ(x), either elementary or composite. In the presence of other matter field, the transformation φ(x) → φ(x) + constant can generate a negative pressure, like the cosmological constant. In this picture, our universe can be thought as a very large bag, similar to the much smaller MIT bag model for a single nucleon.

  19. POSSIBILITIES OF UAS FOR MARITIME MONITORING

    Directory of Open Access Journals (Sweden)

    A. Klimkowska

    2016-06-01

    Full Text Available In the last few years, Unmanned Aircraft Systems (UAS have become more important and its use for different application is appreciated. At the beginning UAS were used for military purposes. These successful applications initiated interest among researchers to find uses of UAS for civilian purposes, as they are alternative to both manned and satellite systems in acquiring high-resolution remote sensing data at lower cost while long flight duration. As UAS are built from many components such as unmanned aerial vehicle (UAV, sensing payloads, communication systems, ground control stations, recovery and launch equipment, and supporting equipment, knowledge about its functionality and characteristics is crucial for missions. Therefore, finding appropriate configuration of all elements to fulfill requirements of the mission is a very difficult, yet important task. UAS may be used in various maritime applications such as ship detection, red tide detection and monitoring, border patrol, tracking of pollution at sea and hurricane monitoring just to mention few. One of the greatest advantages of UAV is their ability to fly over dangerous and hazardous areas, where sending manned aircraft could be risky for a crew. In this article brief description of aerial unmanned system components is introduced. Firstly characteristics of unmanned aerial vehicles are presented, it continues with introducing inertial navigation system, communication systems, sensing payloads, ground control stations, and ground and recovery equipment. Next part introduces some examples of UAS for maritime applications. This is followed by suggestions of key indicators which should be taken into consideration while choosing UAS. Last part talks about configuration schemes of UAVs and sensor payloads suggested for some maritime applications.

  20. Possibilities of Uas for Maritime Monitoring

    Science.gov (United States)

    Klimkowska, A.; Lee, I.; Choi, K.

    2016-06-01

    In the last few years, Unmanned Aircraft Systems (UAS) have become more important and its use for different application is appreciated. At the beginning UAS were used for military purposes. These successful applications initiated interest among researchers to find uses of UAS for civilian purposes, as they are alternative to both manned and satellite systems in acquiring high-resolution remote sensing data at lower cost while long flight duration. As UAS are built from many components such as unmanned aerial vehicle (UAV), sensing payloads, communication systems, ground control stations, recovery and launch equipment, and supporting equipment, knowledge about its functionality and characteristics is crucial for missions. Therefore, finding appropriate configuration of all elements to fulfill requirements of the mission is a very difficult, yet important task. UAS may be used in various maritime applications such as ship detection, red tide detection and monitoring, border patrol, tracking of pollution at sea and hurricane monitoring just to mention few. One of the greatest advantages of UAV is their ability to fly over dangerous and hazardous areas, where sending manned aircraft could be risky for a crew. In this article brief description of aerial unmanned system components is introduced. Firstly characteristics of unmanned aerial vehicles are presented, it continues with introducing inertial navigation system, communication systems, sensing payloads, ground control stations, and ground and recovery equipment. Next part introduces some examples of UAS for maritime applications. This is followed by suggestions of key indicators which should be taken into consideration while choosing UAS. Last part talks about configuration schemes of UAVs and sensor payloads suggested for some maritime applications.

  1. Investigation of Energy Saving Possibilities in Buildings

    Directory of Open Access Journals (Sweden)

    Edita Milutienė

    2010-04-01

    Full Text Available Normal 0 false false false MicrosoftInternetExplorer4 st1\\:*{behavior:url(#ieooui } /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-fareast-font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} Buildings sector is the largest single energy end-user in the EU. There are numerous possibilities to save energy in buildings. This research deals with the analysis of the possibilities to save energy in buildings of northern latitudes by applying a passive solar energy technique. The article presents results of solar radiation monitoring in Vilnius for a 12 years period and assessment of the possibilities to save heat energy. Data could be used in designing solar houses, calculating passive solar energy gains and evaluating CO2 emissions reduction.

  2. Cognitive hearing aids? Insights and possibilities

    Science.gov (United States)

    Petersen, Eline Borch; Lunner, Thomas

    2015-12-01

    The working memory plays an important role in successfully overcoming adverse listening conditions and should consequently be considered when designing and testing hearing aids. A number of studies have established the relationship between hearing in noise and working memory involvement, but with the Sentence-final Word Identification and Recall (SWIRL) test, it is possible to show that working memory is also involved in listening under favorable conditions and that noise reduction has a positive influence in situation with very little noise. Although the capacity of the working memory is a finite individual size, its involvement can differ with fatigue and other factors and individualization of hearing aids should take this into account to obtain the best performance. A way of individually adapting hearing aids is based on changes in the electrical activity of the brain (EEG). Here we present the possibilities that arise from using EEG and show that ear-mounted electrodes is able to record useful EEG that can be explored for individualization of hearing aids. Such an adaptation could be done based on changes in the electrical activity of the brain (EEG). Here we present the possibilities that arise from using EEG and show that ear-mounted electrodes is able to record useful EEG that can be explored for individualization of hearing aids.

  3. Factors enhancing learning possibilities in digital workshops

    Directory of Open Access Journals (Sweden)

    Christian Kobbernagel

    2014-05-01

    Full Text Available This article presents a study of processes supporting student learning possibilities in digital workshops planned and held at art museums in Denmark. The investigation aims to provide insights into factors enhancing learning possibilities, including the educator’s dialogic performance, experiences of art, and perceived qualities of digital content creation processes in art museum education workshops. To address the research question of what conditional and processual factors can be said to support learning possibilities, a model was developed on the basis of fieldwork and theories of media education, art pedagogy and motivation. The model was then analyzed using structural equation modelling (SEM on data collected (N= 502 after workshops in two museums. The results suggest that the dialogic performance of museum educators, a positive art experience and positive perceptions of working with digital media are factors that strongly support student participation and reflection – although to various degrees. The findings also show that, in cases in which students are disinterested and see little value in participating during the workshop, this amotivation is likely to be lower when their art experiences and their perceptions of the media production process are positive. 

  4. Kauffman's adjacent possible in word order evolution

    CERN Document Server

    Ferrer-i-Cancho, Ramon

    2015-01-01

    Word order evolution has been hypothesized to be constrained by a word order permutation ring: transitions involving orders that are closer in the permutation ring are more likely. The hypothesis can be seen as a particular case of Kauffman's adjacent possible in word order evolution. Here we consider the problem of the association of the six possible orders of S, V and O to yield a couple of primary alternating orders as a window to word order evolution. We evaluate the suitability of various competing hypotheses to predict one member of the couple from the other with the help of information theoretic model selection. Our ensemble of models includes a six-way model that is based on the word order permutation ring (Kauffman's adjacent possible) and another model based on the dual two-way of standard typology, that reduces word order to basic orders preferences (e.g., a preference for SV over VS and another for SO over OS). Our analysis indicates that the permutation ring yields the best model when favoring pa...

  5. Tetany: Possible adverse effect of bevacizumab

    Directory of Open Access Journals (Sweden)

    S R Anwikar

    2011-01-01

    Full Text Available Background: Bevacizumab a recombinant humanized monoclonal antibody was approved in 2004 by US FDA for metastatic colorectal cancer. It is reported to cause potentially serious toxicities including severe hypertension, proteinuria, and congestive heart failure. Aim: To correlate adverse event tetany with the use of bevacizumab. Materials and Methods : World Health Organization′s Uppsala Monitoring Centre, Sweden, for reporting of adverse drug reactions from all over the world, identified 7 cases with tetany-related symptoms to bevacizumab from four different countries. These 7 patients reported to UMC database developed adverse events described as musculoskeletal stiffness (1, muscle spasm (1, muscle cramps (1, lock jaw or jaw stiffness (4, and hypertonia (1, with hypocalcaemia. Results: After detailed study of the possible mechanism of actions of bevacizumab and factors causing tetany, it is proposed that there is a possibility of tetany by bevacizumab, which may occur by interfering with calcium metabolism. Resorption of bone through osteoclasts by affecting VEGF may interfere with calcium metabolism. Another possibility of tetany may be due to associated hypomagnesaemia, hypokalemia, or hyponatremia. Conclusions: Tetany should be considered as a one of the signs. Patient on bevacizumab should carefully watch for tetany-related symptoms and calcium and magnesium levels for their safety.

  6. Possibilities and challenges for biosurfactants use in petroleum industry.

    Science.gov (United States)

    Perfumo, Amedea; Rancich, Ivo; Banat, Ibrahim M

    2010-01-01

    Biosurfactants are a group of microbial molecules identified by their unique capabilities to interact with hydrocarbons. Emulsification and de-emulsification, dispersion, foaming, wetting and coating are some of the numerous surface activities that biosurfactants can achieve when applied within systems such as immiscible liquid/liquid (e.g., oil/water), solid/ liquid (e.g., rock/oil and rock/water) and gas/liquid. Therefore, the possibilities of exploiting these bioproducts in oil-related sciences are vast and made petroleum industry their largest possible market at present. The role of biosurfactants in enhancing oil recovery from reservoirs is certainly the best known; however they can be effectively applied in many other fields from transportation of crude oil in pipeline to the clean-up of oil storage tanks and even manufacturing of fine petrochemicals. When properly used, biosurfactants are comparable to traditional chemical analogues in terms of performances and offer advantages with regard to environment protection/conservation. This chapter aims at providing an up-to-date overview of biosurfactant roles, applications and possible future uses related to petroleum industry.

  7. 第4代Murex HCV Ag/Ab联合检测试剂在血液筛查中的应用价值%Study on the possibility of the application of Murex HCV Ag/Ab combination (version 4.0) assay in blood

    Institute of Scientific and Technical Information of China (English)

    冷婵; 邱艳; 修冰水; 龚晓燕; 郑静; 查祎; 王全立

    2012-01-01

    Objective To investigate the application of the Murex HCV Ag/Ab combination (version 4.0) assay for blood screening. Methods 987 HCV-Ab reactive and gray zone samples were collected from routine blood screening and detected by both the Murex HCV Ag/Ab combination assay and Murex HCV Ab reagent. And verification test were carried out by RIBA and HCV NAT test. Results The positive rate of Murex HCV Ag/Ab combination assay and the Murex HCV Ab assay was 73.3% and 75.4% respectively, the negative rate was 95.8% and 90.8% and the final total positive rate was 85.8% and 84.0% respectively. The positive compliance rate between Murex HCV Ag/Ab combination and Murex HCV Ab assay was 76.7%, the negative compliance rate was is 94.5% and the total compliance rate was 87.6%. Among 123 inconsistent samples, 5 were RIBA negative /RNA positive,Murex HCV Ag/Ab positive for 4 samples (including confirmed window period sample); Murex HCV Ab was positive in only one sample; for 15 RIBA positive and RNA negative samples, 5 samples were positive by Murex HCV Ag/Ab and 10 samples were positive by Murex HCV Ab. Conclusions The RIBA negative and RNA positive samples could be efficiently detected out by Murex HCV Ag/Ab combination assay. Because the low compliance rate between Murex HCV Ag/Ab combination and Murex HCV Ab assay and the low detection rate of both system, we recommend the conjunction application of Murex HCV Ag/Ab combination and the Murex HCV Ab assay for blood screening. The double -check for HCV EIA blood screening strategy can help to reduce the possibility of transfusion transmitted infectious diseases.%目的 探讨第4代Murex HCV Ag/Ab联合检测试剂在血液筛查中的应用价值.方法 应用Murex HCV Ag/Ab联合检测试剂与Murex HCV Ab检测试剂,对987份血液筛查中HCV抗体初筛阳性和灰区标本及1份确认窗口期标本进行比较检测,应用RIBA、病毒核酸检测试剂进行补充验证实验,并对结

  8. Possibilities of Laser Processing of Paper Materials

    Science.gov (United States)

    Stepanov, Alexander; Saukkonen, Esa; Piili, Heidi

    Nowadays, lasers are applied in many industrial processes: the most developed technologies include such processes as laser welding, hybrid welding, laser cutting of steel, etc. In addition to laser processing of metallic materials, there are also many industrial applications of laser processing of non-metallic materials, like laser welding of polymers, laser marking of glass and laser cutting of wood-based materials. It is commonly known that laser beam is suitable for cutting of paper materials as well as all natural wood-fiber based materials. This study reveals the potential and gives overview of laser application in processing of paper materials. In 1990's laser technology increased its volume in papermaking industry; lasers at paper industry gained acceptance for different perforating and scoring applications. Nowadays, with reduction in the cost of equipment and development of laser technology (especially development of CO2 technology), laser processing of paper material has started to become more widely used and more efficient. However, there exists quite little published research results and reviews about laser processing of paper materials. In addition, forest industry products with pulp and paper products in particular are among major contributors for the Finnish economy with 20% share of total exports in the year 2013. This has been the standpoint of view and motivation for writing this literature review article: when there exists more published research work, knowledge of laser technology can be increased to apply it for processing of paper materials.

  9. Toward a possible next geomagnetic critical transition?

    Science.gov (United States)

    Qamili, Enkelejda; De Santis, Angelo; Wu, Lixin

    2014-05-01

    The geomagnetic field is subject to possible reversals or excursions of polarity during its temporal evolution. Considering the characteristics of the recent geomagnetic field, a possible imminent geomagnetic reversal or excursion would not be completely unexpected. In that case, such a phenomenon would represent one of the very few natural hazards that are really global. The South Atlantic Anomaly (SAA) is a great depression of the geomagnetic field strength at the Earth's surface, caused by a reverse magnetic flux in the terrestrial outer core. In analogy with critical point phenomena characterized by some cumulative quantity, we fit the surface extent of this anomaly over the last 400 yr with power law or logarithmic functions in reverse time, also decorated by log-periodic oscillations, whose final singularity (a critical point tc) reveals a great change in the near future (2034±3 yr), when the SAA area reaches almost a hemisphere. An interesting aspect that has recently been found is the possible direct connection between the SAA and the global mean sea level (GSL). That the GSL is somehow connected with SAA is also confirmed by the similar result when an analogous critical-like fit is performed over GSL: the corresponding critical point (2033±11 yr) agrees, within the estimated errors, with the value found for the SAA. From this result, we point out the intriguing conjecture that tc would be the time of no return, after which the geomagnetic field could fall into an irreversible process of a global geomagnetic transition that could be a reversal or excursion of polarity.

  10. Toward a possible next geomagnetic transition?

    Science.gov (United States)

    De Santis, A.; Qamili, E.; Wu, L.

    2013-12-01

    The geomagnetic field is subject to possible reversals or excursions of polarity during its temporal evolution. Considering that: (a) in the last 83 million yr the typical average time between one reversal and the next (the so-called chron) is around 400 000 yr, (b) the last reversal occurred around 780 000 yr ago, (c) more excursions (rapid changes in polarity) can occur within the same chron and (d) the geomagnetic field dipole is currently decreasing, a possible imminent geomagnetic reversal or excursion would not be completely unexpected. In that case, such a phenomenon would represent one of the very few natural hazards that are really global. The South Atlantic Anomaly (SAA) is a great depression of the geomagnetic field strength at the Earth's surface, caused by a reverse magnetic flux in the terrestrial outer core. In analogy with critical point phenomena characterized by some cumulative quantity, we fit the surface extent of this anomaly over the last 400 yr with power law or logarithmic functions in reverse time, also decorated by log-periodic oscillations, whose final singularity (a critical point tc) reveals a great change in the near future (2034 ± 3 yr), when the SAA area reaches almost a hemisphere. An interesting aspect that has recently been found is the possible direct connection between the SAA and the global mean sea level (GSL). That the GSL is somehow connected with SAA is also confirmed by the similar result when an analogous critical-like fit is performed over GSL: the corresponding critical point (2033 ± 11 yr) agrees, within the estimated errors, with the value found for the SAA. From this result, we point out the intriguing conjecture that tc would be the time of no return, after which the geomagnetic field could fall into an irreversible process of a global geomagnetic transition that could be a reversal or excursion of polarity.

  11. Toward a possible next geomagnetic transition?

    Directory of Open Access Journals (Sweden)

    A. De Santis

    2013-09-01

    Full Text Available The geomagnetic field is subject to possible reversals or excursions of polarity during its temporal evolution. Considering that: (a the typical average time between one reversal and the next (the so-called chron is around 300 000 yr, (b the last reversal occurred around 780 000 yr ago, (c more excursions (rapid changes of polarity can occur within the same chron and (d the geomagnetic field dipole is currently decreasing, a possible imminent geomagnetic reversal or excursion would not be completely unexpected. In that case, such a phenomenon would represent one of the very few natural hazards which are really global. The South Atlantic Anomaly (SAA is a great depression of the geomagnetic field at the Earth's surface, caused by a reverse magnetic flux in the terrestrial outer core. In analogy with critical point phenomena characterised by some cumulative quantity, we fit the surface extent of this anomaly over the last 400 yr with power or logarithmic functions in reverse time, also decorated by log-periodic oscillations, whose final singularity (a critical point tc reveals a great change in the near future (2034 ± 3 yr, when the SAA area reaches almost a hemisphere. An interesting aspect that has been recently found is the possible direct connection between the SAA and the global mean sea level (GSL. That the GSL is somehow connected with SAA is also confirmed from the similar result when an analogous critical-like fit is performed over GSL: the corresponding critical point (2033 ± 11 yr agrees, within the estimated errors, with the value found for SAA. From this result, we point out the intriguing conjecture that tc would be the time of no return, after which the geomagnetic field could fall into an irreversible process of a global geomagnetic transition that could be a reversal or excursion of polarity.

  12. Possibility for use essential oils in veterinary medicine and animal husbandry with special emphasis on oregano oil

    OpenAIRE

    Vučinić Marijana; Nedeljković-Trailović Jelena; Trailović Saša; Ivanović Saša; Milovanović Mirjana; Krnjaić Dejan

    2012-01-01

    The paper reviews the latest studies on possible applications of oregano essential oil in veterinary medicine and animal livestock production. The first part of the paper deals with the definition of essential oils, possibilities for their extraction from plants, possibilities for their application in human and veterinary medicine, the interest of a science in essential oils, and, essential oils classification based on their use in human and veterinary medi...

  13. Possible observations of the epoch of reionization

    Science.gov (United States)

    Doroshkevich, A. G.; Pilipenko, S. V.

    2011-07-01

    We consider possibilities for presently operating and planned infrared, submillimeter, and millimeter telescopes for observations of the epoch of reionization in the Universe, i.e., of the sources of ultraviolet radiation that have caused the reionization (galaxies, quasars, etc.) and the ionized intergalactic medium. Along with direct observations of such sources in the optical and infrared, we analyze the feasibility of observations of the intergalactic gas, as well as fluctuations of the temperature and polarization of the cosmic microwave background due to inhomogeneities in the reionization process.

  14. A patient with back pain: therapy possibilities

    Directory of Open Access Journals (Sweden)

    P. R. Kamchatnov

    2013-01-01

    Full Text Available Low back pain (LBP is one of the most common clinical syndromes associated with the high rate of temporary disability and sizable material costs. The choice of adequate therapy for LBP requires that primary diseases that can be responsible for the occurrence of pain should be excluded. While choosing an analgesic, there must be a balance between its efficacy and the possible risk for undesirable side effects. One of the drugs that have proven effective in treating patients with LBP is ketoprofen (ketonal, the diversity of whose formulations allows maximally individualized therapy.

  15. How is a philosophy of photography possible?

    Directory of Open Access Journals (Sweden)

    Savchuk Valery

    2015-01-01

    Full Text Available This paper focuses on the following question: how is philosophy of anything possible? Where lies the boundary of specialisation area beyond which the term “philosophy” loses not only its strength, but also its meaning? When we talk about specific genre, for example, graphic art or sculpture we use the term “philosophy” in a broader, metaphorical sense. Why then should philosophy of photography be any different? All of the abovementioned questions are discussed in the present article. Philosophy of photography is, indeed, a legitimate discipline, just as philosophy of language, philosophy of science and technology and philosophy of politics are.

  16. On the possibility of electronic DNA nanobiochips

    CERN Document Server

    Lakhno, V D; 10.1021/ct6003438

    2013-01-01

    We have considered as a theoretical possibility for the development of a nanobiochip the operation principle of which is based on measuring conductance in single-stranded and double-stranded DNA. Calculations have demonstrated that in the majority of cases the conductance of double-stranded nucleotides considerably exceeds that of single-stranded ones. The results obtained are in agreement with recent experiments on measuring the oligonucleotide conductance. It has been shown that an electronic biochip containing 11 nucleotide pairs will recognize approximately 97% sequences. It has also been demonstrated that the percentage of identifiable sequences will grow with the sequence length.

  17. Is an ethical status confessionis possible?

    Directory of Open Access Journals (Sweden)

    Alfred Rauhaus

    2009-11-01

    Full Text Available This article argues that it is possible to declare a status confessionis on account of ethical issues. Discussions of the last 50 years confirm this. The article clarifies under what circumstances a status confessionis may be declared. It is always necessary to indicate clearly that the confession of the church is affected by the ethical situation in question. It is not suffi cient to give a general reference to the gospel or to the teaching of Christ as the reason for declaring a status confessionis.

  18. On the Possibility of Electronic DNA Nanobiochips.

    Science.gov (United States)

    Lakhno, V D; Sultanov, V B

    2007-05-01

    We have considered as a theoretical possibility for the development of a nanobiochip the operation principle of which is based on measuring conductance in single-stranded and double-stranded DNA. Calculations have demonstrated that in the majority of cases the conductance of double-stranded nucleotides considerably exceeds that of single-stranded ones. The results obtained are in agreement with recent experiments on measuring the oligonucleotide conductance. It has been shown that an electronic biochip containing 11 nucleotide pairs will recognize ≈97% sequences. It has also been demonstrated that the percentage of identifiable sequences will grow with the sequence length.

  19. Investigation of possible sun-weather relationships

    Energy Technology Data Exchange (ETDEWEB)

    Businger, S

    1978-01-01

    Statistical correlations between anomalous solar activity (as denoted by large solar flares, active plages, and interplanetary magnetic sector boundaries) and the circulation of the troposphere are reviewed. Two indices (measuring atmospheric vorticity and mean zonal geostrophic flow in the northern hemisphere) are analyzed in an effort to reveal possible sun-weather relationships. The result of this analysis provides no additional statistical evidence for a connection between solar activity and the weather. Finally, physical mechanisms that have been suggested to explain the claimed correlations are discussed.

  20. MOMO syndrome: a possible third case.

    Science.gov (United States)

    Zannolli, R; Mostardini, R; Hadjistilianou, T; Rosi, A; Berardi, R; Morgese, G

    2000-10-01

    This report describes a 5-year-old girl, mildly mentally retarded, with the following characteristics: macrocephaly; severe obesity; ocular abnormalities (right optic disk coloboma and left choroidal coloboma); short stature; and recurvation of the femur. The case is sporadic with no consanguinity between the parents. The condition was diagnosed tentatively as MOMO syndrome (Macrosomia, Obesity, Macrocephaly, and Ocular Abnormalities) (MIM, 157980), because of the presence of short stature, in contrast with the large stature of the only two previously described cases. It is the third possible example of this rare syndrome to be described in the literature, with some new clinical findings presented.

  1. A possible link between food and mood

    DEFF Research Database (Denmark)

    Jørgensen, Bettina Merete Pyndt; Hansen, Julie Torpe; Krych, Lukasz

    2014-01-01

    Major depressive disorder is a debilitating disease in the Western World. A western diet high in saturated fat and refined sugar seems to play an important part in disease development. Therefore, this study is aimed at investigating whether saturated fat or sucrose predisposes mice to develop...... behavioral symptoms which can be interpreted as depression-like, and the possible influence of the gut microbiota (GM) in this. Fourty-two mice were randomly assigned to one of three experimental diets, a high-fat, a high-sucrose or a control diet for thirteen weeks. Mice on high-fat diet gained more weight...

  2. Thermal desalination in GCC and possible development

    KAUST Repository

    Darwish, Mohamed Ali

    2013-06-28

    The Water Desalination and Reuse Center in King Abdulla University of Science and Technology, in Saudi Arabia, held a workshop on thermal desalination on the 11th and 12th of March, 2013. This paper was presented as part of a lecture at the workshop. It presents the status and possible developments of the two main thermal desalination systems processing large quantities of seawater in the Gulf Cooperation Council, multi-stage flash, and thermal vapor compression systems. Developments of these systems were presented to show how these systems are competing with the more energy-efficient seawater reverse osmosis desalting. © 2013 © 2013 Balaban Desalination Publications. All rights reserved.

  3. Elimination of onchocerciasis from Africa: possible?

    Science.gov (United States)

    Mackenzie, Charles D; Homeida, Mamoun M; Hopkins, Adrian D; Lawrence, Joni C

    2012-01-01

    Human onchocerciasis, a parasitic disease found in 28 African countries, six Latin American countries and Yemen, causes blindness and severe dermatological problems. In 1987, efforts to control this infection shifted from vector approaches to include the mass distribution of ivermectin - a drug donated by Merck & Co. for disease control in Africa and for disease elimination in the Americas. Currently, almost 25 years later, with the Americas being highly successful and now approaching elimination, new evidence points towards the possibility of successful elimination in Africa. We suggest several major changes in the programmatic approach that through focused goal-directed effort could achieve global elimination of onchocerciasis by 2025.

  4. The possiblity of the impossible family?

    DEFF Research Database (Denmark)

    Nissen, Maria Appel

    of social problems in the context of the Danish Welfarestate, the analysis shows that it is possible that social systems reproduce and eventually produce new social problems, and that this take place along the production of riskcommunications concerning the child at risk and the childs's need for love......This paper presents preliminary results of a ph.d. thesis based on a comparative qualitative research in two 24-hour institutions performing family treatment and observation as well as evaluation of parental skills. On the basis of some theoretical and empircal reflections on the observation...

  5. New possibilities for weed control in conventional soybeans

    Directory of Open Access Journals (Sweden)

    Petersen, Jan

    2014-02-01

    Full Text Available In field trials in was investigated, if the use of the in Germany new active ingredient imazamox enlarge the possibilities of post emergence weed control in soybeans. Furthermore new herbicide strategies were tested on efficacy and selectivity in soybeans. The use of imazamox was very selective and showed a relative broad spectrum of controlled weed species. However, efficacy of imazamox must be supported by a pre-emergence treatment and in most cases by a tank mix partner. For example cleavers (Galium aparine can not be controlled by imazamox. Tankmixtures of imazamox and bentazon indicated an antagonism. Efficacy to some weed species was reduced compared to solo application. The low dose concept – three applications of low doses at cotyledon stage of weeds led to some success. However, these strategies must be further investigated, before they can be recommended to commercial farming practice. All herbicide strategies tested showed some surviving weed species. This indicates that choice of herbicides, dose rates and application strategies must be done very careful and site specific.

  6. The antimicrobial possibilities of green tea

    Directory of Open Access Journals (Sweden)

    Wanda C Reygaert

    2014-08-01

    Full Text Available Green tea is a popular drink, especially in Asian countries, although its popularity continues to spread across the globe. The health benefits of green tea, derived from the leaves of the Camellia sinensis plant, have been studied for many years. Fairly recently, researchers have begun to look at the possibility of using green tea in antimicrobial therapy, and the potential prevention of infections. The particular properties of catechins found in the tea have shown promise for having antimicrobial effects. There are four main catechins (polyphenols found in green tea: (--epicatechin (EC, (--epicatechin-3-gallate (ECG, (--epigallocatechin (EGC, and (--epigallocatechin-3-gallate (EGCG. Three of these, ECG, EGC, and EGCG have been shown to have antimicrobial effects against a variety of organisms. These catechins have exhibited a variety of antimicrobial mechanisms. The results of studies on the antimicrobial effects of green tea have shown that the potential for preventive and therapeutic purposes is present. Further data collection on studies performed with human consumption during the course of infections, and studies on the occurrence of infections in populations that consume regular amounts of green tea will be necessary to complete the picture of its antimicrobial possibilities.

  7. Food, Tourism and Health: a Possible Sinergy?

    Directory of Open Access Journals (Sweden)

    Silvana Hrelia

    2015-06-01

    Full Text Available Food is a significant aspect of the tourist’s experience of a destination. While the term “wine and food tourism ” is too often addressed only to the taste of the product, the more aseptic definition of “food tourism” wants to focus the attention also on the health properties of local products. Healthy eating is not about strict nutrition philosophies, staying unrealistically thin, or depriving ourselves of the foods we love. Rather, it is about feeling great, having more energy, stabilizing our mood, and keeping ourselves as healthy as possible, all of which can be achieved by learning some nutrition basics and using them in a way that works for us. We can expand our range of healthy food choices and learn how to plan ahead to create and maintain a tasty, healthy diet. Not only the psychological, but also the physical benefits of tourism appear to have gained increasing importance and healthy nutrition represents one of the most important determinants. Food tourism can be considered a potential benefit for human health.Understanding tourists’ needs and wants in terms of healthy food consumption is of paramount importance to hospitality businesses. Food, tourism and health could really be a possible synergy.

  8. Ground as a possible heat pump source

    Energy Technology Data Exchange (ETDEWEB)

    Lazzarin, R. [Padova Univ. (Germany). Dipt. di Tecnica e Gestione die Istemi Industriali

    2001-06-01

    Heat pumps are devices that can increase the thermal level of heat taken from an available source. Their performances are usually very sensible to the temperatures. This is the reason why sources different from the outside air are welcome, since that source is thermally unfavourable. The ground is a possible very favourable source: temperature variations are damped in the ground so much the more deeper one descends. The variations are also delayed, so that in the coldest period one can find equality very good thermal levels. The two main used systems are: horizontal tubes at a depth between 0.8 and 1.5m and vertical tubes. This last technology has gained an increasing popularity with depths which are sometimes deeper than 100m. It interests a large volume of ground with a comparatively small surface area. It is a technology already widespread in Switzerland (where more than 15.000 ground heat pumps were installed in these years), Germany and Austria. It could be a very favourable technology also in Italy and other mediterranean countries both for the presence of good thermal levels underground with excellent characteristics of heat exchange and for the possible use of the ground as a suitable summer thermal sink. (orig.)

  9. Possible ways of future social development

    Directory of Open Access Journals (Sweden)

    Zak L.

    2016-01-01

    Full Text Available The authors deal with a question, which is hard to answer considering the context of the future of the social evolution. The authors suppose that one should ask rather about overcoming the current wave of individualism than about overcoming the current form of capitalism. Individualism dismantles any society and it is necessary to react by building stable dual relationships. It highlights the key role of a family. Collectivism, as well as individualism, are not able to create any kind of social structure and lead the society into the liquid of chaos or into the motionless totality. It states that the economic security of various societies is to certain extent affected by all possible production factors and that the reason of the success of their functioning is a balance between power, wealth and public support. It points out that it is necessary to keep a couple and its relationship as a basic element in theory as well as in practice. In legitimate cases of a production practise, it is possible to consider the human individual as the element. It condemns inhumane artificial terms such as “homo economicus”, human resources or human capital. In the conclusions, the authors appeal to restore humanity in society by the contribution of each individual and his interpersonal relationships.

  10. The Possibilities of Slovakian Pyrethrum Production

    Directory of Open Access Journals (Sweden)

    Štefan Tóth

    2012-01-01

    Full Text Available This paper discusses possibilities for pyrethrum Chrysanthemum cinerariaefolium(Trevir. Vis. production in southern regions of Slovakia, with an emphasis on target marketing,management constraints and further research. Pyrethrum is not a traditionalcrop in Slovakia but prospects have opened up for its cultivation. The high yields andquality of some suitable pyrethrum ecotypes provide the grounds for effective field productionunder favorable conditions. Pyrethrum yielding 1.275 t of dried flowers per hectareand having at least 1.5% pyrethrum content can be a profitable and highly lucrativecrop with an economic result ranging from 413 to 1071 € per ha. A SWOT analysisrevealed that pyrethrum production in Slovakia could take a course of an offensivestrategy. However, intensive production of this commodity needs further development.Prospects for this non-traditional crop in Slovakia are also promising in terms of developmentof farming systems in which plant protection products of botanical origin wouldbe welcome. Improved processing and stabilization of extract would further increasethe possibilities.

  11. From Tragical to the Possible Clinical

    Directory of Open Access Journals (Sweden)

    Loiva Maria De Boni Santos

    2015-11-01

    Full Text Available The article describes an intervention research conducted in a city of southern Brazil with users of alcohol and other drugs considered "nonadherent" to the treatment offered in psychosocial care network in the region. Sustaining an inclusive approach and anti-prohibitionist, the study identify the paths taken by drug users in the territory in order to identify "nodes" of the network (rituals, strategies, services, affections. This can indicate a possible Care Clinic based on affection and bond. It is discussed the polarization of the political debate about drugs. It was made a bet on Harm Reduction as a guideline care from the perspective of overcoming the resentment commonly impregnated in the practices and discourses from the area. Among the results was possible to identify the collective production of a rap music in the middle of the investigative process, this "gives another tone" to the experiences and positions of the patients, pointing to the creation of new existential territories as an alternative to public policies committed with health promotion.

  12. Sequence of tenses: playing with possibilities

    Directory of Open Access Journals (Sweden)

    Bohdan Ulašin

    2012-12-01

    Full Text Available The aim of this article is to analyse the sequence of tenses in Spanish, a phenomenon typical of the Romance languages. Our purpose is to systematize and formulate the rules of use by means of examples with graphical representations. We focus on such cases of use of the sequence of tenses where it is possible to apply a “double-access interpretation”, i. e. which allows the possibility of choosing between reference points: with the actual time (the moment of speech or with the main clause. This double interpretation is to be found in all three types of time relationships: simultaneousness, priority and posteriority. Some pairs differ semantically; others are used according to the preferences of the speaker with no change of meaning. Most examples are subordinate noun clauses, nonetheless we included examples of other types of clauses as well (e.g. relative, reason clauses. We also analyze the problem of the sequence of tenses where the main verb is in the conditional tense.

  13. Cognitive sciences and psychoanalysis: a possible convergence.

    Science.gov (United States)

    Imbasciati, Antonio

    2003-01-01

    This paper compares the psychoanalytic description of inner experience with that of the cognitive sciences, which see it in terms of information processing. The two observational standpoints relate to the same mental events. The author considers the possibility of bringing the two descriptions into line with each other and of their mutual translation. The "information" processed in the deep, unconscious, affective, internal experience of a relational context must be identified. This may be possible if a general theory of mental functioning that allows for the data of psychoanalytic observation in terms of semantics, memory, and communication can be formulated. The author examines the theoretical tradition of psychoanalysis, and draws attention to the uncertainties to which Freud's metapsychology gives rise. The energy/drive theory was not only descriptive and clinical in nature, but also had explanatory value, which put psychoanalysis in contact with the other mental sciences of the time. This explanatory value is no longer valid today, and psychoanalytic theories since Freud seem to have disregarded the aspect of "explanation," leaving a theoretical void that has isolated psychoanalysis from the other sciences of the mind. The author contends that object theories may be an appropriate starting point for the exploration of experience in terms of learning processes and of memory traces, and suggests a psychoanalytic cognitivism, coupled with a personal theory to explain the development of the mind.

  14. Simposium 19: Teaching Offers Many Possibilities

    Directory of Open Access Journals (Sweden)

    Denise Vaz Macedo

    2014-08-01

    Full Text Available K-Education(PortugueseChair: V. TrindadeBayardo Torres; Clovis Wannmacher; Denise Macedo  Teaching Offers Many Possibilities Denise Vaz Macedo Biochemistry Department, Biology Institute, Unicamp, Campinas, Brazil.   In the last years my research lines are maintained exclusively through my biochemistry teaching activities at graduation and specialization course (360h. The teaching methodology used was developed over these 20 years into the classroom research. It is based on five practical activities carried out at the initial moment by the students themselves, who monitor the effects of different physical activity situations through the measurement of some plasma metabolites on point of care devices. After instructions the students perform the exercises collects and tabulate the data generated and document all the doubts arising. The educational goal right now is to show that the theory related to muscle contraction, the ATP-producing metabolic pathways is linked to their profession. At adequate moments each group presents to the whole class the practical activity carried out, the data and the doubts produced. After a fully discussion the students are able to relate the data to the studied theory. Also the initial doubts are clarified. A questionnaire applied before and after the discipline indicates the learning effectiveness of this method. Some other results: the students who have demonstrated special interest in the classroom normally join into de lab. Simultaneously they are also prepared for the teaching activity. The demand of specialization course is greater than the supply. The financial resources generated are expressive and administered by the University Foundation. They are fully applied to purchase permanent and consumption materials and for the payment of eventual scholarships for lab researchers. The publication in indexed journals has been constant and regular, and the obtained experimental results always return to the

  15. The possibility of life proliferation from Enceladus

    Science.gov (United States)

    Czechowski, Leszek

    2016-07-01

    Enceladus is a medium sized icy satellite (MIS) of Saturn. MIS are built of mixtures of rocks and ices. According to [1]: "For life to have emerged […] on the early Earth, a sustained source of chemically transducible energy was essential. The serpentinization process is emerging as an increasingly likely source of that energy" (see also [2]). We consider here conditions for origin of life in the early Enceladus and later proliferation of the life. Mass of serpentinite: The serpentinization on the Earth is often considered with hydrothermal activity in neovolcanic zones along mid-oceanic spreading centers. However, only in small part the hydrothermal activity really occurs. A simple calculations (e.g. [3]) indicate that mass fraction of silicates in Enceladus is ~0.646, hence the total mass of its silicate is ~6.97 10^1^9 kg. [4] considered the process of differentiation and core forming in Enceladus. He found that the result of differentiation is a relatively cold core of loosely packed grains with water between them. The entire core of Enceladus was probably permeable. This could lead to formation of extensive hydrothermal convective systems. It indicates that total mass of serpententinized silicate in Enceladus could be larger than on the Earth. The evolution of temperature in the Enceladus interior for the first a few hundreds Myr is given in [4]. He found that the temperature allows for existing the life even in the center of the satellite. It is possible that for hundreds of Myr the conditions in Enceladus were more favorable for origin of life than on the Earth. Proliferation of life: The low gravity of the Enceladus and its volcanic activity make transport possible. Note that the low temperature of plumes from active region of Enceladus does not kill the organisms. The primitive bacteria could leave the Enceladus with volcanic jets in the same way as particles of the E ring. Other mechanisms could transport particles to terrestrial planets. Therefore it

  16. Finitary and Infinitary Mathematics, the Possibility of Possibilities and the Definition of Probabilities

    CERN Document Server

    Donald, M J

    2003-01-01

    Some relations between physics and finitary and infinitary mathematics are explored in the context of a many-minds interpretation of quantum theory. The analogy between mathematical ``existence'' and physical ``existence'' is considered from the point of view of philosophical idealism. Some of the ways in which infinitary mathematics arises in modern mathematical physics are discussed. Empirical science has led to the mathematics of quantum theory. This in turn can be taken to suggest a picture of reality involving possible minds and the physical laws which determine their probabilities. In this picture, finitary and infinitary mathematics play separate roles. It is argued that mind, language, and finitary mathematics have similar prerequisites, in that each depends on the possibility of possibilities. The infinite, on the other hand, can be described but never experienced, and yet it seems that sets of possibilities and the physical laws which define their probabilities can be described most simply in terms ...

  17. Developing the smallest possible medical cyclotron

    CERN Multimedia

    Katarina Anthony

    2011-01-01

    Imagine a portable medical cyclotron operated in a conventional radioactive facility at a hospital. Imagine a nurse or technician switching it on and producing isotopes at the patient’s bedside. Sounds like science fiction? Think again.   CERN has teamed up with Spain’s national scientific research centre (CIEMAT) to develop an avant-garde cyclotron to be used for Positron Emission Tomography (PET). “We plan to make a cyclotron that doesn't need an insulated building or ‘vault’: a cyclotron small enough to fit inside a hospital lift,” explains Jose Manuel Perez, who is leading the CIEMAT/CERN collaboration. “It will be the smallest possible medical cyclotron for single patient dose production and will dramatically reduce costs for hospitals.” While PET technology has transformed imaging techniques, many of its medical benefits have remained confined to highly specialised hospitals. “Studies have foun...

  18. The possible order L'ordine possibile

    Directory of Open Access Journals (Sweden)

    Francesco Saverio Chesi

    2011-10-01

    Full Text Available

    La questione dell’ordine sembra porsi in termini ineludibili per una riflessione che, muovendo dalla kantiana logica della relazione, sappia cogliere - nel gioco tra Analitica e Dialettica - la portata metafisica del metodo analogico. Nondimeno, la tensione dell’intero arco categoriale verso la modalità porta poi a rifocalizzare la questione stessa come domanda sul nesso tempo, spazio, possibilità.

    The question of order inevitably proposes a reflection aiming at comprehending, from the play between Analytic and Dialectic, the metaphysical significance of the analogical method, the start point being Kant’s logic of relationship. Nevertheless, the tension of the entire categorical arc toward modality leads to refocus the question on the connection among time, space, and possibility.

  19. Possible interrelations among chemical freezeout conditions

    CERN Document Server

    Tawfik, A; Habashy, D M; Mohamed, M T; Abbas, E

    2016-01-01

    At thermal equilibrium, different chemical freezeout conditions have been proposed so far. They have an ultimate aim of proposing a universal description for the chemical freezeout parameters ($T_{ch}$ and $\\mu_b$), which are to be extracted from the statistical fitting of different particle ratios measured at various collision energies with calculations from thermal models. A systematic comparison between these conditions is presented. The physical meaning of each of them and their sensitivity to the hadron mass cuts are discussed. Based on availability, some of them are compared with recent lattice calculations. We found that most of these conditions are thermodynamically equivalent, especially at small baryon chemical potential. We propose that further crucial consistency tests should be performed at low energies. The fireball thermodynamics is another way of guessing conditions describing the chemical freezeout parameters extracted from high-energy experiments. We endorse the possibility that the various ...

  20. Resonant diffraction of synchrotron radiation: New possibilities

    Science.gov (United States)

    Ovchinnikova, E. N.; Mukhamedzhanov, E. Kh.

    2016-09-01

    Resonant diffraction of synchrotron radiation (SR) is a modern method of studying the structure and properties of condensed matter that can be implemented on third-generation synchrotrons. This method allows one to investigate local properties of media (including magnetic and electronic ones) and observe thermal vibrations, defects, and orbital and charge orderings. A brief review of the advance provided by SR resonant diffraction is presented, and the capabilities of this method for analyzing phase transitions are considered in more detail by the example of potassium dihydrogen phosphate and rubidium dihydrogen phosphate crystals. It is shown that the investigation of the temperature dependence of forbidden reflections not only makes it possible to observe the transition from para- to ferroelectric phase, but also gives information about the proton distribution at hydrogen bonds.

  1. Digital Learning Environments: New possibilities and opportunities

    Directory of Open Access Journals (Sweden)

    Otto Peters

    2000-06-01

    Full Text Available This paper deals with the general problem whether and, if so, how far the impact of the digitised learning environment on our traditional distance education will change the way in which teachers teach and learners learn. Are the dramatic innovations a menace to established ways of learning and teaching or are they the panacea to overcome some of the difficulties of our system of higher learning and to solve some of our educational problems caused by the big and far-reaching educational paradigm shift? This paper will not deal with technical or technological achievements in the field of information and communication which are, of course, revolutionary and to be acknowledged and admired. Rather, the digital learning environment will be analysed from a pedagogical point of view in order to find out what exactly are the didactic possibilities and opportunities and what are its foreseeable disadvantages.

  2. Considering a possible future for Digital Journalism

    Directory of Open Access Journals (Sweden)

    Mark DEUZE

    2017-01-01

    Full Text Available Developments shaping digital journalism seem to speeding up at the start of the 21st century. Social media enable radical new ways to gather and verify sources and information. Hardware and software power innovative storytelling formats, combining platforms and channels, adding interactivity to the news experience. And the global news industry is quickly becoming a networked industry, with startups and other forms of entrepreneurial journalism springing up all over the world. In this essay, I consider a possible future for digital journalism by briefly reviewing first findings from a series of case studies of 21 new small-sized journalism enterprises operating in 11 countries (spread across 5 continents. The overarching research question: seen through their eyes, what does the future of (digital journalism look like? The answers are hopeful.

  3. Quantitative Information Flow - Verification Hardness and Possibilities

    CERN Document Server

    Yasuoka, Hirotoshi

    2010-01-01

    Researchers have proposed formal definitions of quantitative information flow based on information theoretic notions such as the Shannon entropy, the min entropy, the guessing entropy, and channel capacity. This paper investigates the hardness and possibilities of precisely checking and inferring quantitative information flow according to such definitions. We prove that, even for just comparing two programs on which has the larger flow, none of the definitions is a k-safety property for any k, and therefore is not amenable to the self-composition technique that has been successfully applied to precisely checking non-interference. We also show a complexity theoretic gap with non-interference by proving that, for loop-free boolean programs whose non-interference is coNP-complete, the comparison problem is #P-hard for all of the definitions. For positive results, we show that universally quantifying the distribution in the comparison problem, that is, comparing two programs according to the entropy based definit...

  4. X-ray diffraction comparator - new possibilities.

    Science.gov (United States)

    Brytov, I A; Dmitriev, G D; Ivanov, V N; Klevtsov, S A

    1997-01-01

    We have studied the possibilities to determine precisely the lattice constants of quartz using an X-ray diffractometer-comparator. This device has double-crystal optical scheme, continuously swinging crystal-monochromator and an original angular reference system. The measurement strategy uses the difference in angular positions of two different Bragg planes relative the third one. On assumption that the wavelength of the used radiation is known with accuracy of ± 1.2,ppm, the accuracy of determined lattice constants is estimated in ± 5×10-5Å. The described measurement strategy proves to be efficient in measuring the changes of the lattice constants with temperature and in precision testing of a quartz single-crystal homogeneity. We discuss also the features of other instruments for the automatic sorting of quartz blanks in groups by the cut angle, which use the same monochromator pendulum system.

  5. Possibility of Large EW Penguin contribution

    CERN Document Server

    Mishima, S; Mishima, Satoshi; Yoshikawa, Tadashi

    2005-01-01

    We discuss a possibility of large electroweak(EW) penguin contribution in B-->K pi and pi pi. The recent experimental data may be still suggesting that there are some discrepancies between the data and theoretical estimations. In B --> K pi decays, to explain several theoretical relations among the branching ratios, a slightly large electroweak penguin contribution and large strong phase differences or quite large color suppressed tree contribution seem to be needed. The contributions should appear also in B --> pi pi. We show, as an example, a solution to solve the discrepancies in both B --> K pi and B --> pi pi. It may be suggesting to need the large electroweak penguin contribution with new weak phases and some SU(3) breaking effects by new physics in both QCD and electroweak penguin type processes.

  6. The generation of possible space layouts

    DEFF Research Database (Denmark)

    Christensen, Jesper Thøger

    2014-01-01

    The general scope of this paper is to present the development of an approach for the generation of possible space layouts in the early stages of design. The approach sets out to bridge the gap between the free form brainstorming of the sketching designer and the deterministic parametric model......, through springs that connects everything to everything and allows topology to change, opposed to the strict hierarchy and constraints of traditional parametric design. Thus instead of the topology being determined by initial constraints, the layout will be generated by probabilities of spaces to connect...... of the computational designer. A new responsive design tool is developed; applying physical based modelling techniques to a computational environment. Springs and particles automates the initial placement and sizing of the spaces, and allows continuous user and software interaction. Keeping the design process alive...

  7. Egon Schiele as trickster: possible approaches

    Directory of Open Access Journals (Sweden)

    Daniel Franco de Oliveira

    2012-12-01

    Full Text Available Egon Schiele, in his self-portraits, investigates, with a careful and extremely critical view, the psychological and emotional and produces an extense work in 10 years. The ambiguities and the many transformations in which he submits himself allow him to trace parallels between his work and the trickster, a mythic figure who transits between borderlines, crossing its boundaries, trick-player/deceiver, the cheater, an entity of multiple forms. This article aims to study the nude self-portrait of Schiele from 1910, analyze it e clarify possible similarities found from the comparison between him and the six characteristics from the multicultural and multiformal Trickster created by William Hynes and presented in the chapter Mapping Trickster Characteristics from the book Mythical Trickster Figures.

  8. Is It Possible to Predict Strong Earthquakes?

    CERN Document Server

    Polyakov, Yuriy S; Solovyeva, Anna B; Timashev, Serge F

    2015-01-01

    The possibility of earthquake prediction is one of the key open questions in modern geophysics. We propose an approach based on the analysis of common short-term candidate precursors (2 weeks to 3 months prior to strong earthquake) with the subsequent processing of brain activity signals generated in specific types of rats (kept in laboratory settings) who reportedly sense an impending earthquake few days prior to the event. We illustrate the identification of short-term precursors using the groundwater sodium-ion concentration data in the time frame from 2010 to 2014 (a major earthquake occurred on February 28, 2013), recorded at two different sites in the south-eastern part of the Kamchatka peninsula, Russia. The candidate precursors are observed as synchronized peaks in the nonstationarity factors, introduced within the flicker-noise spectroscopy framework for signal processing, for the high-frequency component of both time series. These peaks correspond to the local reorganizations of the underlying geoph...

  9. Some Standard model problems and possible solutions

    Science.gov (United States)

    Barranco, J.

    2016-10-01

    Three problems of the standard model of elementary particles are studied from a phenomenological approach. (i) It is shown that the Dirac or the Majorana nature of the neutrino can be studied by looking for differences in the v-electron scattering if the polarization of the neutrino is considered. (ii) The absolute scale of the neutrino mass can be set if a four zero mass matrix texture is considered for the leptons. It is found that m ν3 ∼⃒ 0.05 eV. (iii) It is shown that it is possible -within a certain class of two Higgs model extensions of the standard model- to have a cancelation of the quadratic divergences to the mass of physical Higgs boson.

  10. Is “Islamic Fundamentalism” Possible?

    Directory of Open Access Journals (Sweden)

    Neşet TOKU

    2015-12-01

    Full Text Available Fundamentalism is the religious Protestant movement that developed upon the spreading of the “millennium” belief, which belongs to the Christian theo-logy, in the USA towards the end of 19th century. Nowadays the word “funda-mentalism” is used, sometimes explicitly and sometimes implicitly, to refer to Islam as an equivalent of intolerance, pro-violence and fanaticism. This propa-ganda is so great that recognition of Islam by a Muslim raises the risk for him to be qualified as fundamentalist. In this essay, we will interrogate whether it is possible or not to establish a relation between fundamentalism, which is a wes-tern phenomenon, and Islam by examining historical and cultural background of the both.

  11. Integrated care across borders: possibilities and complexities

    Directory of Open Access Journals (Sweden)

    Silvia Evers

    2001-09-01

    Full Text Available The main purpose of this practice paper is to describe and analyse the possibilities and complexities of integrated health care across borders. First, we portray an ideal scenario for this type of care with a case of patients suffering from rheumatoid arthritis and living in the Dutch-Belgian frontier area. It shows how cross border care enhances continuity of care/tailor-made care and the other way around. Secondly, based on different literature sources, we describe actual regulations on health care across borders. We show that these regulations can be a major hindrance to integrated care. This raises questions on the scope and content of policies directed at both cross border and integrated care.

  12. Possible segregation caused by centrifugal titanium casting.

    Science.gov (United States)

    Watanabe, K; Okawa, S; Kanatani, M; Nakano, S; Miyakawa, O; Kobayashi, M

    1996-12-01

    The possibility of the segregation under solidification process using a centrifugal casting machine was investigated using an electron probe microanalyzer with elemental distribution map, line analysis and quantitative analysis. When a very small quantity of platinum was added to local molten titanium during the casting process, macroscopic segregation was observed under conditions of density difference of 0.1 g/cm3 at the most, confirming that the centrifugal force of the casting machine is extremely strong. When a Ti-6Al-4V alloy was cast, however, no macroscopic segregation was observed. The centrifugal force of the casting machine examined in the present study hardly results in the body-force segregation in this titanium alloy.

  13. Ethnic marketing possibilities and its ethics issues

    Directory of Open Access Journals (Sweden)

    Agota Kozma

    2009-12-01

    Full Text Available This paper focuses on the possibilities of ethnic marketing and its ethic connections. The differences found in our face-to-face interviews and analysing questionnaire data will provide opportunities for Hungarian small enterprises. Targeting ethnic groups for marketing purposes results in ethical difficulties. In Hungary, ethnic marketing is yet an inexperienced concept. Based on these ideas the authors examine the ins and outs of using ethnic marketing in case of Germans in Hungary. Consumers with German ethnic attitude really want German products and brands. At the same time, enterprises have to emphasise the products’ “Germanness” and character in a better/stronger way because this can help for better consumer decision making.

  14. Positive Psychology: possible future and clinical derivations

    Directory of Open Access Journals (Sweden)

    Mariana Gancedo

    2015-09-01

    Full Text Available A possible future for the Positive Psychology movement could be to merge it into a new enunciative subsystem of psychology, which is named here as psychoeulogy. Psychoeulogy is defined as: the psychology subsystem that studies psychological well-being, and its conditions, characteristics and promotion. It could be understood as the conceptual reversal of psychopathology. Together, psychoeulogy and psychopathology, can complete the spectre of knowledge about the psyche. The target of this article is to introduce an epistemological model for this future psychoeulogy, and, at the same time, display its derivations on a clinical psychoeulogical model that can integrate the contributions of positive psychology and those of others psychological movements. 

  15. The Multimodal Possibilities of Online Instructions

    DEFF Research Database (Denmark)

    Kampf, Constance

    2006-01-01

    The WWW simplifies the process of delivering online instructions through multimodal channels because of the ease of use for voice, video, pictures, and text modes of communication built into it.  Given that instructions are being produced in multimodal format for the WWW, how do multi......-modal analysis tools help us understand the impact of multimodal channels used in instructions?  This paper looks at Kress and VanLeewan's questions of "how narrative is shaped in a specific mode and how it is reshaped when it appears in different modes?" (2001:128)  In addition, the intersection of linguistics...... and rhetoric is explored as a means of understanding the multimodal possibilities for technical communication genres such as instructions....

  16. Religion and cancer: examining the possible connections.

    Science.gov (United States)

    Crane, Jacquelyn N

    2009-01-01

    Numerous sound scientific studies (cross-sectional and longitudinal) have found a positive correlation between religion and physical and mental health. In particular, there is evidence that demonstrates that religion helps cancer patients better adjust to and cope with their disease, at least psychologically. However, some research suggests that mediating factors associated with religion may explain the positive effects of religion on health. This article argues that even if this is the case, there is still intrinsic value to religion in that the mediators themselves are strongly connected to religion, and therefore religion is important to the patient in terms of coping, support, hope, and meaning. This has possible important implications for clinical practice.

  17. Superbradyons and some possible dark matter signatures

    CERN Document Server

    Gonzalez-Mestres, Luis

    2009-01-01

    Superluminal preons (superbradyons) with a critical speed in vacuum much larger than the speed of light would, if they exist, play a fundamental role as constituents of the physical vacuum. If they are present as free particles in our Universe, they would spontaneously decay by emitting standard particles until they reach a speed equal or close to that of light. They would then form a cosmological sea where the relation between inertial and gravitational masses would differ from conventional Physics. Superbradyons may be at the origin of cosmological and astrophysical phenomena usually associated to dark matter and dark energy. Then, superbradyon spontaneous decays and similar interactions would be candidates to explain data on electron and positron abundances (PAMELA, ATIC, Fermi LAT, HESS, PPB-BETS) considered as possible dark matter signatures.

  18. Microflares as Possible Sources for Coronal Heating

    Indian Academy of Sciences (India)

    Meera Gupta; Rajmal Jain; Jayshree Trivedi; A. P. Mishra

    2008-03-01

    We present a preliminary study of 27 microflares observed by Solar X-ray Spectrometer (SOXS) mission during July 2003 to August 2006. We found that all 27 microflares show the Fe-line feature peaking around 6.7 keV, which is an indicator of the presence of coronal plasma temperature ≥ 9 MK. On the other hand, the spectra of microflares showhybrid model of thermal and non-thermal emission, which further supports them as possible sources of coronal heating. Our results based on the analysis show that the energy relapsed by the microflares is good enough for heating of the active corona. We discuss our results in the light of the hybrid model of microflares production.

  19. Compulsive gambling possibly associated with antiepileptic medication

    Directory of Open Access Journals (Sweden)

    Susanne Storrier

    2014-01-01

    Full Text Available Compulsive gambling is recognized with Parkinson's disease treatment with dopamine agonists but has not been reported with antiepileptic medications (AEMs in epilepsy. This is the first report regarding possible compulsive gambling, provoked by AEMs in a patient with idiopathic generalized epilepsy, who presented with nonconvulsive status epilepticus, having previously not achieved seizure control with carbamazepine, valproate, (VPA, topiramate, gabapentin (GPT, lamotrigine (LTG, and clobazam. Levetiracetam (LEV was added to VPA and GPT, which the patient was already taking and LTG subsequently retrialed. Following the reintroduction of LTG, she lost $4000–5000, which she concealed. With better seizure control, VPA and GPT were withdrawn, leaving her on LEV and LTG. With increased LTG dosage, she lost $50,000, prompting discovery of her gambling.

  20. Computing possibilities in the mid 1990s

    Energy Technology Data Exchange (ETDEWEB)

    Nash, T.

    1988-09-01

    This paper describes the kind of computing resources it may be possible to make available for experiments in high energy physics in the mid and late 1990s. We outline some of the work going on today, particularly at Fermilab's Advanced Computer Program, that projects to the future. We attempt to define areas in which coordinated R and D efforts should prove fruitful to provide for on and off-line computing in the SSC era. Because of extraordinary components anticipated from industry, we can be optimistic even to the level of predicting million VAX equivalent on-line multiprocessor/data acquisition systems for SSC detectors. Managing this scale of computing will require a new approach to large hardware and software systems. 15 refs., 6 figs.

  1. Current possibilities in occlusal caries management

    Directory of Open Access Journals (Sweden)

    Hrvoje Jurić

    2013-11-01

    Full Text Available Dental caries is a multifactorial disease that affects most populations throughout the world and it is still the primary cause of oral pain and tooth loss. The occlusal surfaces of posterior teeth are the most vulnerable sites for dental caries due to their anatomy. Therefore, the aim of the following article is to summarize current knowledge on occlusal caries development and the possibilities of its prevention. Although the overall caries rate today has fallen for populations in industrialized countries, the rate of occlusal surface caries has not decreased. This may be explained with fact that topically applied fluorides and their mode of action prevent caries better on smooth than on occlusal surfaces. As we know, tooth decay of first permanent molars causes a great deal of different short and long term difficulties for patients. Therefore, there is a continuous need for implementation of programs for caries prevention in permanent teeth. Nowadays, we like to treat our patients by minimally invasive methods. A very important step in our effective preventive treatment is sealing pits and fissures as a cornerstone of occlusal caries management. Reliable assessment of caries activity is also very important for defining treatment needs and plans. A very important decision, which should be made during occlusal caries management, is the selection of restorative material according to the treatment plan. Conclusion. Current possibilities in occlusal caries prevention and management are very effective. Therefore, dentists today do not have any excuse for avoiding the philosophy of Minimally Invasive Dentistry, especially when we talk about caries management of occlusal surfaces in permanent molars.

  2. Oxidative Damage and Its Possible Mechanism

    Directory of Open Access Journals (Sweden)

    Tingting Wang

    2016-06-01

    Full Text Available Purpose: The paper tries to assess the protective effect of fisetin against •OH-induced DNAdamage, then to investigate the possible mechanism.Methods: The protective effect was evaluated based on the content of malondialdehyde(MDA. The possible mechanism was analyzed using various antioxidant methods in vitro,including •OH scavenging (deoxyribose degradation, •O2- scavenging (pyrogallolautoxidation, DPPH• scavenging, ABTS•+ scavenging, and Cu2+-reducing power assays.Results: Fisetin increased dose-dependently its protective percentages against •OH-inducedDNA damage (IC50 value =1535.00±29.60 μM. It also increased its radical-scavengingpercentages in a dose-dependent manner in various antioxidants assays. Its IC50 values in•OH scavenging, •O2- scavenging, DPPH• scavenging, ABTS•+ scavenging, and Cu2+-reducing power assays, were 47.41±4.50 μM, 34.05±0.87 μM, 9.69±0.53 μM, 2.43±0.14μM, and 1.49±0.16 μM, respectively.Conclusion: Fisetin can effectively protect DNA against •OH-induced oxidative damagepossibly via reactive oxygen species (ROS scavenging approach, which is assumed to behydrogen atom (H• and/or single electron (e donation (HAT/SET pathways. In the HATpathway, the 3’,4’-dihydroxyl moiety in B ring of fisetin is thought to play an importantrole, because it can be ultimately oxidized to a stable ortho-benzoquinone form.

  3. Possible values of UV index in Serbia

    Directory of Open Access Journals (Sweden)

    Letić Milorad

    2008-01-01

    Full Text Available INTRODUCTION UV Index is an indicator of human exposure to solar ultraviolet (UV rays. The numerical values of the UV Index range from 1-11 and above. There are three levels of protection against UV radiation; low values of the UV Index - protection is not required, medium values of the UV Index - protection is recommended and high values of the UV Index - protection is obligatory. The value of the UV Index primarily depends on the elevation of the sun and total ozone column. OBJECTIVE The aim of the study is to determine the intervals of possible maximal annual values of the UV Index in Serbia in order to determine the necessary level of protection in a simple manner. METHOD For maximal and minimal expected values of total column ozone and for maximal elevation of the sun, the value of the UV Index was determined for each month in the Northern and Southern parts of Serbia. These values were compared with the forecast of the UV Index. RESULTS Maximal clear sky values of the UV Index in Serbia for altitudes up to 500m in May, June, July and August can be 9 or even 10, and not less than 5 or 6. During November, December, January and February the UV Index can be 4 at most. During March, April, September and October the expected values of the UV Index are maximally 7 and not less than 3. The forecast of the UV Index is within these limits in 98% of comparisons. CONCLUSION The described method of determination of possible UV Index values showed a high agreement with forecasts. The obtained results can be used for general recommendations in the protection against UV radiation.

  4. CAD Integration : new optical design possibilities

    Science.gov (United States)

    Haumonte, Jean-Baptiste; Venturino, Jean-Claude

    2005-09-01

    The development of optical design and analysis tools in a CAD software can help to optimise the design, size and performance of tomorrow's consumer products. While optics was still held back by software limitations, CAD programs were moving forward in leaps and bounds, improving manufacturing technologies and making it possible to design and produce highly innovative and sophisticated products. The problem was that in the past, 'traditional' optical design programs were only able to simulate spherical and aspherical lenses, meaning that the optical designers were limited to designing systems which were a series of imperfect lenses, each one correcting the last. That is why OPTIS has created the first optical design program to be fully integrated into a CAD program. The technology is available from OPTIS in an integrated SOLIDWORKS or CATIA V5 version. Users of this software can reduce the number of lenses needed in a system. Designers will now have access to complex surfaces such as NURBS meaning they will now be able to define free shape progressive lenses and even improve on optical performances using fewer lenses. This revolutionary technology will allow mechanical designers to work on optical systems and to share information with optical designers for the first time. Previously not possible in a CAD program you may now determine all the optical performances of any optical system, providing first order and third order performances, sequential and non-sequential ray-tracing, wavefront surfaces, point spread function, MTF, spot-diagram, using real optical surfaces and guaranteeing the mechanical precision necessary for an optical system.

  5. Possible hepatotoxicity of chronic marijuana usage

    Directory of Open Access Journals (Sweden)

    Paulo Borini

    Full Text Available CONTEXT: Hepatotoxicity is a potential complication from the usage of various illicit drugs, possibly consequent to their liver metabolism, but information on this is scarce in the medical literature. OBJECTIVE: To study the occurrence of clinical and laboratory hepatic alterations in chronic marijuana users, from the use of marijuana on its own or in association with other legal or illicit drugs. TYPE OF STUDY: transversal study SETTING: Hospital Espírita de Marília, Marília, São Paulo, Brazil PARTICIPANTS: The study was made among 123 patients interned in the Hospital Espírita de Marília from October 1996 to December 1998, divided into 3 groups: 26 (21% using only marijuana, 83 (67.5% using marijuana and crack, and 14 (11.4% consuming marijuana and alcohol. PROCEDURES AND MAIN MEASUREMENTS: Patients were examined clinically with special emphasis on types of drugs used, drug intake route, age when consumption began, length and pattern of usage, presence of tattooing, jaundice, hepatomegaly and splenomegaly. Serum determinations of total proteins, albumin, globulin, total and fractions of bilirubin, aspartate (AST and alanine (ALT aminotransferases, alkaline phosphatase (AP, gamma-glutamyltransferase and prothrombin activity were performed. RESULTS: Among users of only marijuana, hepatomegaly was observed in 57.7% and splenomegaly in 73.1%, and slightly elevated AST (42.3%, ALT (34.6% and AP (53.8%. The three groups did not differ significantly in the prevalence of hepatomegaly, splenomegaly and hepatosplenomegaly. The group using both marijuana and alcohol showed the highest prevalence of alterations and highest levels of aminotransferases. Mean AP levels were above normal in all groups. CONCLUSIONS: Chronic marijuana usage, on its own or in association with other drugs, was associated with hepatic morphologic and enzymatic alterations. This indicates that cannabinoids are possible hepatotoxic substances.

  6. EDUCATION FOR PEACE IN HIGH SCHOOL, IS THAT POSSIBLE?

    Directory of Open Access Journals (Sweden)

    Alma Delia Hernández Román

    2015-01-01

    Full Text Available In this trial it is discuss with particular attention the troubles surrounding the teachers and the Education for peace. Currently the teachers in high school education find themselves in an unprecedented situation due to the recent obligatory nature of this education level, the equally recent education reforms and the application of the competency education approach. Formed in many cases for teachers with no pedagogical formation or experience, the staff of high school education faces the institutional requirements with very few elements to be able to satisficed. In this context it began to be introduced the alternative of the Education for peace, but it is necessary to reflect upon the real possibilities of the schools, their authorities, their teachers and their students to accomplish it.

  7. Distribution of possible sunshine durations over rugged terrains of China

    Institute of Scientific and Technical Information of China (English)

    ZENG Yan; QIU Xinfa; MIAO Qilong; LIU Changming

    2003-01-01

    Based on the digital elevation model (DEM), a new model for calculating possible sunshine duration (PSD) is completely described. Using this model, monthly PSD with resolution of 1 km×1 km for the rugged topography of China is calculated. Results suggest that terrain has robust effect on PSD, particularly in winter when a lower sun elevation angle exists. Besides, the proposed model taking the DEM data as the input has an ability to process mass of data and is applicable to satellite image processing platforms or Geographic Information System (GIS). The PSD (in hours) is provided in the same way as other kinds of spatial information and can be employed as basic geographic data for relevant studies as well.

  8. Possible domestication of uranium oxides using biological assistance reduction

    Directory of Open Access Journals (Sweden)

    Slah Hidouri

    2017-01-01

    Full Text Available Uranium has been defined in material research engineering field as one of the most energetic radioactive elements in the entire Mendeleev periodic table. The manipulation of uranium needs higher theories and sophisticated apparatus even in nuclear energy extraction or in many other chemical applications. Above the nuclear exploitation level, the chemical conventional approaches used, require a higher temperature and pressure to control the destination of ionic form. However, it has been discovered later that at biological scale, the manipulation of this actinide is possible under friendly conditions. The review summarizes the relevant properties of uranium element and a brief characterization of nanoparticles, based on some structural techniques. These techniques reveal the common link between chemical approaches and biological assistance in nanoparticles. Also, those biological entities have been able to get it after reduction. Uranium is known for its ability to destroy ductile materials. So, if biological cell can really reduce uranium, then how does it work?

  9. Relational frame theory and Skinner's Verbal Behavior: A possible synthesis.

    Science.gov (United States)

    Barnes-Holmes, D; Barnes-Holmes, Y; Cullinan, V

    2000-01-01

    The current article suggests a possible synthesis of Skinner's (1957) treatment of verbal behavior with the more recent behavioral interpretation of language known as relational frame theory. The rationale for attempting to combine these two approaches is first outlined. Subsequently, each of the verbal operants described by Skinner is examined and subjected to a relational frame analysis. In each case, two types of operants are identified; one based on direct contingencies of reinforcement and the other based on arbitrarily applicable relational responding. The latter operants are labeled verbal because they can be distinguished from other forms of social behavior, and they appear to possess the symbolic or referential qualities often ascribed to human language. By applying relational frame theory to Skinner's verbal operants, we aim to contribute towards the development of a modern behavior-analytic research agenda in human language and cognition.

  10. Smooth Rotation Enhanced As-Rigid-As-Possible Mesh Animation.

    Science.gov (United States)

    Levi, Zohar; Gotsman, Craig

    2015-02-01

    In recent years, the As-Rigid-As-Possible (ARAP) shape deformation and shape interpolation techniques gained popularity, and the ARAP energy was successfully used in other applications as well. We improve the ARAP animation technique in two aspects. First, we introduce a new ARAP-type energy, named SR-ARAP, which has a consistent discretization for surfaces (triangle meshes). The quality of our new surface deformation scheme competes with the quality of the volumetric ARAP deformation (for tetrahedral meshes). Second, we propose a new ARAP shape interpolation method that is superior to prior art also based on the ARAP energy. This method is compatible with our new SR-ARAP energy, as well as with the ARAP volume energy.

  11. Reinventing the Possibilities: Academic Literacy and New Media

    Directory of Open Access Journals (Sweden)

    Ryan 'rylish' Moeller

    2007-01-01

    Full Text Available This webtext demonstrates the possibilities of using new media to teach students critical literacy skills applicable to the 21st century. It is a manifesto for what the authors think writing scholars should be teaching in general-education "writing" classes like first-year composition. In order to answer the question of what we should teach, we have to ask what kinds of academic literacy, if any, we value. The authors argue here that rhetorical theory is a productive way to theorize how meaning is made among new media texts, their designers, and their readers. They use the Ancient Greek concepts of topoi and commonplace to explain how designers and readers enter into a space of negotiated meaning-making when converging upon new media texts. That negotiated space offers a new-media space for learning critical literacies by means other than research papers. As examples, they discuss two student texts and the literacies they demonstrate.

  12. Cyanoacrylate for Intraoral Wound Closure: A Possibility?

    Directory of Open Access Journals (Sweden)

    Parimala Sagar

    2015-01-01

    Full Text Available Wound closure is a part of any surgical procedure and the objective of laceration repair or incision closure is to approximate the edges of a wound so that natural healing process may occur. Over the years new biomaterials have been discovered as an alternate to conventional suture materials. Cyanoacrylate bioadhesives are one among them. They carry the advantages of rapid application, patient comfort, resistance to infection, hemostatic properties, and no suture removal anxiety. Hence this study was undertaken to study the effect of long chain cyanoacrylate as an adhesive for intraoral wound closure and also to explore its hemostatic and antibacterial effects. Isoamyl-2-cyanoacrylate (AMCRYLATE was used as the adhesive in the study. In conclusion isoamyl cyanoacrylate can be used for intraoral wound closure, as an alternative to sutures for gluing the mucoperiosteum to bone, for example, after impaction removal, periapical surgeries, and cleft repair. Its hemostatic and antibacterial activity has to be further evaluated.

  13. Automated weed detection in the field - possibilities and limits

    Directory of Open Access Journals (Sweden)

    Pflanz, Michael

    2016-02-01

    Full Text Available Unmanned Aerial Vehicles (UAV have become omnipresent and adequate tools to generate high-resolution spatial data of agricultural cropland. Their implementation into remote sensing approaches of weeds provides suitable applications for a site-specific herbicide management. In general, an increasingly use of innovative technologies gradually leads from agricultural research into the practical application. This requires an evaluation of possibilities and limits of UAV-based remote sensing procedures. While spectrals from UAVs are being used already for mapping needs of nutrient or water, the image supported weed detection is much more complex and at the moment not relevant in practice. In this regard, there is a lack of weed and crop differentiation through spectral analyses and object-based approaches separate different plants not species-specific or are not adapted to morphologic changes of the growth. Moreover, there is a need for alternative positioning techniques without GPS, as it is required for a precise optical imaging analysis at low altitudes. To evaluate the possibilities and limitations of automated weed identification regarding the optical and sampling requirements, flights were carried out with a hexacopter at an altitude of 5 m over agricultural crop land with variable weed patches. The altitude was controlled by the GPS-autopilot. Images were captured at geo-referenced points and the number of different weed species was simultaneously determined by manually counting. The required optical resolution on the ground was estimated by comparing the number of weeds between image analysis on the PC and with the field rating data.

  14. UV Habitable Zones Further Constrain Possible Life

    Science.gov (United States)

    Kohler, Susanna

    2017-02-01

    Where should we search for life in the universe? Habitable zones are traditionallydetermined based on the possibility of liquid water existing on a planet but ultraviolet (UV) radiation also plays a key role.The UV Habitable ZoneSchematic showing how the traditional habitable zones location and width changes around different types of stars. The UV habitable zone also hasdifferent locations and widths depending on the mass and metallicity of the star. [NASA/Kepler Mission/Dana Berry]Besides the presence of liquid water, there are other things life may need to persist. For life as we know it, one important elementis moderate UV radiation: if a planet receives too little UV flux, many biological compounds cant be synthesized. If it receives too much, however, then terrestrial biological systems (e.g. DNA) can be damaged.To determinethe most likely place to findpersistent life, we should therefore look for the region where a stars traditional habitable zone, within which liquid water is possible, overlaps with its UV habitable zone, within which the UV flux is at the right level to support life.Relationship between the stellar mass and location of the boundaries of the traditional and UV habitable zones for a solar-metallicity star. din and dout denote inner and outer boundaries, respectively. ZAMS and TMS denote when the star joins and leaves the main sequence, respectively. The traditional and UV habitable zones overlap only for stars of 11.5 solar masses. [Adapted from Oishi and Kamaya 2016]Looking for OverlapIn a recent study, two scientists from the National Defense Academy of Japan, Midori Oishi and Hideyuki Kamaya, explored howthe location of this UV habitable zone and that of its overlap with the traditional habitable zone might be affected by a stars mass and metallicity.Oishi and Kamaya developed a simple evolutional model of the UV habitable zone in stars in the mass range of 0.084 solar masses with metallicities of roughly solar metallicity (Z=0.02), a

  15. [An expert system neurology--possibilities and limitations].

    Science.gov (United States)

    Bickel, A; Grunewald, M

    2006-12-01

    We present an expert system Neurology, which was developed completely on basis of the commercial available data base program Filemaker-7.0. At present it covers approximately 400 diagnoses of neurological and psychiatric diseases. After the input of cardinal symptoms, course and localisation of the disease the program calculates a first set of possible differential diagnoses and asks for additional symptoms or the performance of apparative diagnostics to investigate the final diagnose. At first, the performance of the expert system was tested with 15 predetermined neurological case reports. Users with different previous knowledge of Neurology performed the input. In this test the program was able to identify the correct diagnose in nearly all cases and the diagnostic proposals were superior to those of the users with minor neurological training. In a second test with real patient data, the rate of correct diagnoses was approximately 80%. In summary, the used computer algorithms proved as appropriate for the aim of giving Neurological diagnoses. Possible additional applications could be student training or the use as interdisciplinary reference work.

  16. Probability as Possibility Spaces: Communicating Uncertainty to Policymakers

    Science.gov (United States)

    Stiso, C.

    2015-12-01

    One problem facing the sciences is communicating results and recommendations to policymakers. This is perhaps particularly difficult in the geosciences where results are often based on probabilistic models, as probability is often and unduly equated with a specific kind of uncertainty or unreliability in the results. This leads to a great deal of miscommunication and misguided policy decisions. It is, then, valid to ask how scientists should talk about probability, uncertainty, and models in a way that correctly conveys what the users of these models intend. What I propose is a new way to think and, importantly, talk about probability which will hopefully make this much more transparent to both users and policy makers. Rather than using a frequentist (prior percentages) or Bayesian (observer uncertainty) framework, we should talk about probability as a tool for defining a possibility space for measurements. This model is conceptually simple and makes probability a tool of refinement rather than a source of inaccuracy. A similar possibility-space model has proven useful in the climate sciences and there is good reason to believe it will have similar applications in hydrology.

  17. Problems and possibilities of using telephone technology in education

    Directory of Open Access Journals (Sweden)

    Danilović Mirčeta S.

    2002-01-01

    Full Text Available The paper explores the possibilities of using telephone technology in educational process. It is emphasized how valuable audio-teleconference and tutorial teaching are by means of telephone technology but skepticism is also expressed concerning the possibilities of using this type of technology in our educational system. The causes for such skepticism are mostly to be found in our economic conditions, inadequacy of material sources and technical problems i.e. underdeveloped telephone networks. Telephone technology is not suitable for work with a whole class. It is primarily intended for one-to-one teaching, in the USA most often called 'tutorship'. Accordingly, 'telephone tutorship' is the most widespread form of telephone application in the teaching process. When it is being accomplished, a student (user has only to have a telephone at home or that public phone network is operating and he/she can communicate with his/her 'tutor', (teacher. 'A tutor' can be at home and communicate with his/her students or at a local learning center wherefrom he/she can communicate with a student. Students can also be at their local learning center or at home.

  18. Uncertainity in risk assessment: Combining probabilities and possibilities

    Energy Technology Data Exchange (ETDEWEB)

    Guyonnet, D.; Bourgine, B. [BRGM, Orleans (France); Dubois, D. [Univeriste Paul Sabatier, Toulouse (France); Come, B. [ANTEA, Orleans (France); Chiles, J.-P. [Ecole des Mines de Paris (France). Centre de Geostatistique

    2003-07-01

    Uncertainty is an unavoidable component of the estimation of the risk of exposure to soil pollutants. Information regarding parameters that influence the risk of exposure are generally fraught with uncertainty. This uncertainty may have essentially two origins: randomness (due in particular to variability phenomena) and incompleteness (i.e., when information regarding parameter values is simply lacking). The ideal way to address uncertainty due to randomness is to collect data, perform a statistical analysis and identify a probability distribution which accounts for the randomness. When information is incomplete, or statistical data are not available, human experts can supply information on parameter values. Such subjective information can be tainted with various defects (ambiguity, vagueness, imprecision, etc.) and can be represented in various fashions (probability density functions, possibility distributions, uncertainty intervals, etc.). While different types of uncertainty may warrant different models of uncertainty representation, the question arises as to how several modes of representation can be accommodated in the same estimation of risk? This paper provides some clear insight into the fundamental differences between probabilities and possibilities, and the consequences of assuming one or the other when representing uncertainty. This paper presents the so-called 'hybrid' approach (Guyonnet et al., 2003) which combines probability distribution functions (PDF's) and possibility distributions (fuzzy numbers) in the same computation of risk. Because it allows one to take advantage of the 'rich' information provided by the PDF's, while retaining the conservative character of fuzzy calculus to account for those parameters for which a representation by unique PDF's is not justified by the available data, the hybrid method is believed to hold value in terms of consistency with a 'reasonable' application of the

  19. POSSIBLE CHROMOSPHERIC ACTIVITY CYCLES IN AD LEO

    Energy Technology Data Exchange (ETDEWEB)

    Buccino, Andrea P.; Petrucci, Romina; Mauas, Pablo J. D. [Instituto de Astronomía y Física del Espacio (CONICET-UBA), C.C. 67 Sucursal 28, C1428EHA-Buenos Aires (Argentina); Jofré, Emiliano [Observatorio Astronómico de Córdoba, Córdoba (Argentina)

    2014-01-20

    AD Leo (GJ 388) is an active dM3 flare star that has been extensively observed both in the quiescent and flaring states. Since this active star is near the fully convective boundary, studying its long-term chromospheric activity in detail could be an appreciable contribution to dynamo theory. Here, using the Lomb-Scargle periodogram, we analyze the Ca II K line-core fluxes derived from CASLEO spectra obtained between 2001 and 2013 and the V magnitude from the ASAS database between 2004 and 2010. From both of these totally independent time series, we obtain a possible activity cycle with a period of approximately seven years and a less significant shorter cycle of approximately two years. A tentative interpretation is that a dynamo operating near the surface could be generating the longer cycle, while a second dynamo operating in the deep convection zone could be responsible for the shorter one. Based on the long duration of our observing program at CASLEO and the fact that we observe different spectral features simultaneously, we also analyze the relation between simultaneous measurements of the Na I index (R{sub D}{sup ′}), Hα, and Ca II K fluxes at different activity levels of AD Leo, including flares.

  20. Possible chromospheric activity cycles in AD Leo

    CERN Document Server

    Buccino, Andrea P; Jofré, Emiliano; Mauas, Pablo J D

    2013-01-01

    AD Leo (GJ 388) is an active dM3 flare star extensively observed both in the quiescent and flaring states. Since this active star is near the fully-convective boundary, to study in detail its long-term chromospheric activity could be an appreciable contribution for the dynamo theory. Here, we analyze with the Lomb-Scargle periodogram the Ca II K line-core fluxes derived from CASLEO spectra obtained between 2001 and 2013 and the V magnitude from the ASAS database between 2004 and 2010. From both totally independent time-series, we obtain a possible activity cycle of period $\\sim7$ years and a less-significant shorter one of $\\sim2$ years. A tentative interpretation is that a dynamo operating near the surface could be generating the longer cycle, while a second dynamo operating in the deep convection zone could be responsible for the shorter one. Based on the long duration of our observing program at CASLEO and the fact that we observe simultaneously different spectral features, we also analyze the relation bet...

  1. Possible surface nematic order in iron pnictides

    Science.gov (United States)

    Song, Kok Wee; Koshelev, Alexei

    Nematic fluctuations play important role in the physics of the iron-based superconductors. Indications for weak precursor nematic transition has been found in the compound BaAs2-xPxFe2 [1 ]. However, high-resolution specific-heat measurements did not reveal any bulk transition [2 ]. To resolve this controversy, we consider the possibility of the surface nematic transition preceding the bulk transition. We consider the simplest model of two interacting quasi-two-dimensional electronic bands and explore the free-surface effects on the nematic order. We found that three-dimensional effects suppress the bulk nematic order and therefore this order is enhanced near the surface. [1 ]Kasahara, S., et al. ''Electronic nematicity above the structural and superconducting transition in Ba(As1-xPxFe)2.'' Nature 486.7403 (2012): 382-385. [2 ]Luo, X., et al. ''Antiferromagnetic and nematic phase transitions in Ba(As1-xPxFe)2 studied by ac microcalorimetry and SQUID magnetometry.'' Physical Review B 91.9 (2015): 094512. This work was supported by the Center for Emergent Superconductivity, an Energy FrontierResearch Center funded by the US DOE, Office of Science, under Award No. DEAC0298CH1088.

  2. Possible Lingering Effects of Multiple Past Concussions

    Directory of Open Access Journals (Sweden)

    Grant L. Iverson

    2012-01-01

    Full Text Available Background. The literature on lingering or “cumulative” effects of multiple concussions is mixed. The purpose of this study was to examine whether athletes with a history of three or more concussions perform more poorly on neuropsychological testing or report more subjective symptoms during a baseline, preseason evaluation. Hypothesis. Athletes reporting three or more past concussions would perform more poorly on preseason neurocognitive testing. Study Design. Case-control study. Methods. An archival database including 786 male athletes who underwent preseason testing with a computerized battery (ImPACT was used to select the participants. Twenty-six athletes, between the ages of 17 and 22 with a history of three or more concussions, were identified. Athletes with no history of concussion were matched, in a case-control fashion, on age, education, self-reported ADHD, school, sport, and, when possible, playing position and self-reported academic problems. Results. The two groups were compared on the four neuropsychological composite scores from ImPACT using multivariate analysis of variance followed by univariate ANOVAs. MANOVA revealed no overall significant effect. Exploratory ANOVAs were conducted using Verbal Memory, Visual Memory, Reaction Time, Processing Speed, and Postconcussion Scale composite scores as dependent variables. There was a significant effect for only the Verbal Memory composite. Conclusions. Although inconclusive, the results suggest that some athletes with multiple concussions could have lingering memory deficits.

  3. Dense matter at RAON: Challenges and possibilities

    Science.gov (United States)

    Lee, Yujeong; Lee, Chang-Hwan; Gaitanos, T.; Kim, Youngman

    2016-11-01

    Dense nuclear matter is ubiquitous in modern nuclear physics because it is related to many interesting microscopic and macroscopic phenomena such as heavy ion collisions, nuclear structure, and neutron stars. The on-going rare isotope science project in Korea will build up a rare isotope accelerator complex called RAON. One of the main goals of RAON is to investigate rare isotope physics including dense nuclear matter. Using the relativistic Boltzmann-Uehling-Uhlenbeck (RBUU) transport code, we estimate the properties of nuclear matter that can be created from low-energy heavyion collisions at RAON.We give predictions for the maximum baryon density, the isospin asymmetry and the temperature of nuclear matter that would be formed during 197Au+197Au and 132Sn+64Ni reactions. With a large isospin asymmetry, various theoretical studies indicate that the critical densities or temperatures of phase transitions to exotic states decrease. Because a large isospin asymmetry is expected in the dense matter created at RAON, we discuss possibilities of observing exotic states of dense nuclear matter at RAON for large isospin asymmetry.

  4. Telocytes in liver regeneration: possible roles.

    Science.gov (United States)

    Wang, Fei; Song, Yang; Bei, Yihua; Zhao, Yingying; Xiao, Junjie; Yang, Changqing

    2014-09-01

    Telocytes (TCs) are a novel type of interstitial cells which are potentially involved in tissue regeneration and repair (www.telocytes.com). Previously, we documented the presence of TCs in liver. However, the possible roles of TCs in liver regeneration remain unknown. In this study, a murine model of partial hepatectomy (PH) was used to induce liver regeneration. The number of TCs detected by double labelling immunofluorescence methods (CD34/PDGFR-α, CD34/PDGFR-ß and CD34/Vimentin) was significantly increased when a high level of hepatic cell proliferation rate (almost doubled) as shown by 5-ethynyl-2'-deoxyuridine (EdU) immunostaining and Western Blot of Proliferating cell nuclear antigen (PCNA) was found at 48 and 72 hrs post-PH. Meanwhile, the number of CK-19 positive-hepatic stem cells peaked at 72 hrs post-PH, co-ordinating with the same time-point, when the number of TCs was most significantly increased. Taken together, the results indicate a close relationship between TCs and the cells essentially involved in liver regeneration: hepatocytes and stem cells. It remains to be determined how TCs affect hepatocytes proliferation and/or hepatic stem cell differentiation in liver regeneration. Besides intercellular junctions, we may speculate a paracrine effect via ectovesicles.

  5. [Histamine intolerance--possible dermatologic sequences].

    Science.gov (United States)

    Lugović-Mihić, Liborija; Seserko, Ana; Duvancić, Tomislav; Situm, Mirna; Mihić, Josip

    2012-12-01

    Although histamine intolerance (HIT) is not very frequently encountered, it can have serious consequences. Food intolerance is a non allergic hypersensitivity to food that does not include the immune system even though the symptoms are similar to those of IgE-mediated allergic reactions. HIT apparently develops as a result of an impaired diamine oxidase (DAO) activity due to gastrointestinal disease or through DAO inhibition, as well as through a genetic predisposition which was proven in a number of patients. The intake of histamine-rich foods as well as alcohol or drugs which cause either the release of histamine or the blocking of DAO can lead to various disorders in many organs (gastrointestinal system, skin, lungs, cardiovascular system and brain), depending on the expression of histamine receptors. Dermatologic sequels can be rashes, itch, urticaria, angioedema, dermatitis, eczema and even acne, rosacea, psoriasis, and other. Recognizing the symptoms due to HIT is especially important in treating such patients. The significance of HIT in patients with atopic dermatitis in whom the benefit of a low histamine diet has been proven is becoming increasingly understood recently. Because of the possibility of symptoms affecting numerous organs, a detailed history of symptoms following the intake of histamine-rich foods or drugs that interfere with histamine metabolism is essential for making the diagnosis of HIT. Considering that such symptoms can be the result of multiple factors, the existence of HIT is usually underestimated, but considerable expectations are being made from future studies.

  6. A possible link between food and mood

    DEFF Research Database (Denmark)

    Pyndt Jørgensen, Bettina; Hansen, Julie Torpe; Krych, Lukasz;

    2014-01-01

    Major depressive disorder is a debilitating disease in the Western World. A western diet high in saturated fat and refined sugar seems to play an important part in disease development. Therefore, this study is aimed at investigating whether saturated fat or sucrose predisposes mice to develop...... behavioral symptoms which can be interpreted as depression-like, and the possible influence of the gut microbiota (GM) in this. Fourty-two mice were randomly assigned to one of three experimental diets, a high-fat, a high-sucrose or a control diet for thirteen weeks. Mice on high-fat diet gained more weight...... of immobility in the forced swim test when compared to control mice (p = 0.039) and high-fat fed mice (p = 0.013), and displayed less anxiety than mice on high-fat diet in the triple test (p = 0.009). Behavioral changes were accompanied by a significant change in GM composition of mice fed a high-fat diet...

  7. Quantum Computing: Theoretical versus Practical Possibility

    CERN Document Server

    Paraoanu, G S

    2011-01-01

    An intense effort is being made today to build a quantum computer. Instead of presenting what has been achieved, I invoke here analogies from the history of science in an attempt to glimpse what the future might hold. Quantum computing is possible in principle - there are no known laws of Nature that prevent it - yet scaling up the few qubits demonstrated so far has proven to be exceedingly difficult. While this could be regarded merely as a technological or practical impediment, I argue that this difficulty might be a symptom of new laws of physics waiting to be discovered. I also introduce a distinction between "strong" and "weak" emergentist positions. The former assumes that a critical value of a parameter exists (one that is most likely related to the complexity of the states involved) at which the quantum-mechanical description breaks down, in other words, that quantum mechanics will turn out to be an incomplete description of reality. The latter assumes that quantum mechanics will remain as a universal...

  8. The possibility of life proliferation from Enceladus

    Science.gov (United States)

    Czechowski, Leszek

    2016-04-01

    Introduction: Enceladus is a medium-sized icy satellite (MIS) of Saturn. MIS are built of mixtures of rocks and ices. Enceladus with its radius of 250 km is one of the smallest of MIS, however, it is geologically active. According to [1]: "For life to have emerged […] on the early Earth, a sustained source of chemically transducible energy was essential. The serpentinization process is emerging as an increasingly likely source of that energy. Serpentinization of ultramafic crust would have continuously supplied hydrogen, methane, […] to off-ridge alkaline hydrothermal springs that interfaced with the metal-rich carbonic Hadean Ocean" (see also [2]). We consider here conditions for origin of life in early Enceladus and possible proliferation of the life from this satellite to the rest of Solar System. Mass of serpentinite: The serpentinization on the Earth is found in neovolcanic zones along mid-oceanic spreading centers. However, only in small part of them the hydrothermal activity really occurs. After [3] we consider the following reaction: Mg2SiO4 + MgSiO3 + 2H2O -> Mg3Si2O5(OH)4 . This reaction releases 241 000 J per kg of serpentine produced. Simple calculations (e.g. [4]) indicate that mass fraction of silicatesfmas in Enceladus is ˜0.646, hence the total mass of its silicate is ˜6.97 1019 kg. [4] found that the early core in Enceladus was a relatively cold structure built from loosely packed grains with water between them. At that time, there was not mechanism of removing the water. Since rocks are permeable up to the pressure of ˜300 MPa then the entire core of Enceladus was probably permeable for liquids. This could lead to formation of extensive hydrothermal convective systems. T-p conditions in Enceladus: The pressure in the center of Enceladus is ˜2.3 107 Pa that corresponds to pressure on the depth 2300 m in a terrestrial ocean. The evolution of temperature in the Enceladus interior for the first a few hundreds Myr is considered by [4]. If

  9. Information Support of Regions and Possibilities of Its Further Development

    Directory of Open Access Journals (Sweden)

    J. Vaněk, M. Stočes, P. Šimek, I. Hrbek

    2012-09-01

    Full Text Available The paper presents the results of information and communication technologies (ICT research support in the Czech Republic regions, focused mainly on the problems of mapping cultural heritage together with activities in the area of tourism and business activities connected with it (accommodation, food etc. One possible approach is demonstrated on the example of web portal “Get to know Posumavi – a tourist guide to Posumavi”. This approach integrates the advantages of standard information sources with the Internet application. Moreover, this application provides a clear topographical output. The project is being prepared in co-operation with a chosen local partner, in our case the Posumavi local action group. The under-mentioned solution can be further extended if need be, but we can also understand it as a general-purpose solution which means it can be widely used in other areas of the information support of regions.The knowledge and data presented in the paper were obtained as a result of the Research Program titled “Economy of the Czech Agriculture Resources and Their Efficient Use within the Framework of the Multifunctional Agri-food Systems” of the Czech Ministry of Education, Youth and Sports number VZ MSM 6046070906.

  10. X-optogenetics and U-optogenetics: Feasibility and Possibilities

    CERN Document Server

    Berry, Rachel; Gjesteby, Lars; Wang, Ge

    2014-01-01

    To address these limitations of optogenetics, here we propose two new methods for optogenetic stimulation. The first is x-optogenetics, which uses visible light-emitting nanophosphors stimulated by focused x-rays. This idea is not new but the application to optogenetics is novel. X-rays can penetrate much more deeply than infrared light and could allow for nerve cell stimulation in any part of the brain. In this paper, we discuss the feasibility and possibilities of such a method by describing the advances in nanomaterials, x-ray focusing, and x-ray sources. Also, we discuss concerns when dealing with x-rays such as radiation dosage. Through the use of quantities and assumptions backed by recent literature, manufacturer specifications, and personal correspondence, a full feasibility analysis of x-optogenetics is completed. The second proposed method we explore is u-optogenetics, which is the application of sonoluminescence to optogenetics. Such a technique uses ultrasound waves instead of x-rays to induce lig...

  11. Neutrinos herald possible new physics in Japan

    CERN Multimedia

    2011-01-01

    There’s an embarrassment of choice for my message this week. Firstly, it was great to see a press release from the Japanese T2K (Tokai to Kamioka) experiment on 15 June, signalling not only potentially great physics, but also that the Japanese physics community is getting back on its feet after the earthquake and tsunami. Back home, the LHC is running beautifully...    Crossing the inverse femtobarn threshold so early into this years run is wonderful achievement, and augurs well for the summer conferences. We’ve now reached the stage where a single LHC fill is delivering as much data as the entire 2010 run. And finally, when Council met this week, I was pleased to announce that CERN has received formal confirmation from all five applicants for membership, opening the way to CERN welcoming new members soon. A busy two weeks, then, but what I’d like to focus on is the new result from Japan.   Simply stated, the T2K result shows the first indication of...

  12. Lyellian curves in paleontology: Possibilities and limitations

    Science.gov (United States)

    Stanley, Steven M.; Addicott, Warren O.; Chinzei, Kiyotaka

    1980-09-01

    Since the birth of modern geology, Cenozoic deposits have commonly been dated according to Lyellian percentages (proportions of living species within fossil faunas), but this approach has never been tested. To remedy this situation, we have calculated Lyellian percentages for gastropod and bivalve faunas of Japan and western North America. When plotted against geologic age (determined by independent methods), the percentages for each class form a narrow band that reveals similar patterns of extinction for the two regions and an absence of major pulses of extinction. The plots thus seem to represent useful “standard” curves but display enough spread of data to cast doubt on the value of Lyellian percentages to chronostratigraphy. Our plots do have many other useful applications: (1) They reveal differences in regional patterns of extinction; in particular, they document a Pleistocene mass extinction of Mollusca in the confined seas of the tropical Americas and an unusually low rate of extinction in the enormous tropical Indo-Pacific region. (2) They indicate that gastropods are characterized by higher rates of extinction than bivalves. (3) They provide a mechanism for evaluating differences in rates of extinction between discrete subgroups of taxa, such as tropical species and temperate species, or species with planktic larvae and species with nonplanktic larvae.

  13. Economic aspects of possible residential heating conservation

    Energy Technology Data Exchange (ETDEWEB)

    Hopkowicz, M.; Szul, A. [Technical Univ., Cracow (Poland)

    1995-12-31

    The paper presents methods of evaluation of energy and economy related effects of different actions aimed at conservation in residential buildings. It identifies also the method of selecting the most effective way of distribution funds assigned to weatherization as well as necessary improvements to be implemented within the heating node and the internal heating system of the building. The analysis of data gathered for four 11-stories high residential buildings of {open_quotes}Zeran{close_quotes} type being subject of the Conservation Demonstrative Project, included a differentiated scope of weatherization efforts and various actions aimed at system upgrading. Basing upon the discussion of the split of heat losses in a building as well as the established energy savings for numerous options of upgrading works, the main problem has been defined. It consists in optimal distribution of financial means for the discussed measures if the total amount of funds assigned for modifications is defined. The method based upon the principle of relative increments has been suggested. The economical and energy specifications of the building and its components, required for this method have also been elaborated. The application of this method allowed to define the suggested optimal scope of actions within the entire fund assigned for the comprehensive weatherization.

  14. DEVELOPMENT POSSIBILITIES OF THE HUNGARIAN-UKRAINIAN

    Directory of Open Access Journals (Sweden)

    Pasztor Szabolcs

    2012-12-01

    questionnaire-based survey. With 432 cases collected from 6 micro regions from the Ukrainian side I can measure the possible cross-border dynamics of the borderless situation. With this method I follow the empirical approach of other regionalists who have come to the conclusion that the opening-up of borders can lead to different dynamism. In this way I try to shed new light on the development possibilities and more increased economic interactions the Hungarian-Ukrainian borderland. The most important conclusion of this paper is the fact that with more intensive cross-border interactions not the neighbouring borderaland benefits but centrally located or larger towns in Hungary. In this way I can point to the fact that borderland dynamics could be quite limited in the research area. With this paper I could confirm previous studies and point to the fact that empirical analysis is needed to understand the local dynamism of a borderless space.

  15. Vitiligo: a possible model of degenerative diseases.

    Science.gov (United States)

    Bellei, Barbara; Pitisci, Angela; Ottaviani, Monica; Ludovici, Matteo; Cota, Carlo; Luzi, Fabiola; Dell'Anna, Maria Lucia; Picardo, Mauro

    2013-01-01

    Vitiligo is characterized by the progressive disappearance of pigment cells from skin and hair follicle. Several in vitro and in vivo studies show evidence of an altered redox status, suggesting that loss of cellular redox equilibrium might be the pathogenic mechanism in vitiligo. However, despite the numerous data supporting a pathogenic role of oxidative stress, there is still no consensus explanation underlying the oxidative stress-driven disappear of melanocytes from the epidermis. In this study, in vitro characterization of melanocytes cultures from non-lesional vitiligo skin revealed at the cellular level aberrant function of signal transduction pathways common with neurodegenerative diseases including modification of lipid metabolism, hyperactivation of mitogen-activated protein kinase (MAPK) and cAMP response element-binding protein (CREB), constitutive p53-dependent stress signal transduction cascades, and enhanced sensibility to pro-apoptotic stimuli. Notably, these long-term effects of subcytotoxic oxidative stress are also biomarkers of pre-senescent cellular phenotype. Consistent with this, vitiligo cells showed a significant increase in p16 that did not correlate with the chronological age of the donor. Moreover, vitiligo melanocytes produced many biologically active proteins among the senescence-associated secretory phenotype (SAPS), such as interleukin-6 (IL-6), matrix metallo proteinase-3 (MMP3), cyclooxygenase-2 (Cox-2), insulin-like growth factor-binding protein-3 and 7 (IGFBP3, IGFBP7). Together, these data argue for a complicated pathophysiologic puzzle underlying melanocytes degeneration resembling, from the biological point of view, neurodegenerative diseases. Our results suggest new possible targets for intervention that in combination with current therapies could correct melanocytes intrinsic defects.

  16. Arctic Warming as News - Perils and Possibilities

    Science.gov (United States)

    Revkin, A. C.

    2015-12-01

    A science journalist in his 30th year covering human-driven climate change, including on three Arctic reporting trips, reflects on successes and setbacks as news media, environmentalists and Arctic communities have tried to convey the significance of polar change to a public for which the ends of the Earth will always largely be a place of the imagination.Novel challenges are arising in the 24/7 online media environment, as when a paper by a veteran climate scientist proposing a mechanism for abrupt sea-level rise became a big news story before it was accepted by the open-review journal to which it had been submitted. New science is digging in on possible connections between changing Arctic sea ice and snow conditions and disruptive winter weather in more temperate northern latitudes, offering a potential link between this distant region and the lives of ordinary citizens. As cutting-edge research, such work gets substantial media attention. But, as with all new areas of inquiry, uncertainty dominates - creating the potential for distracting the public and policymakers from the many aspects of anthropogenic climate change that are firmly established - but, in a way, boring because of that.With the challenges, there are unprecedented opportunities for conveying Arctic science. In some cases, researchers on expeditions are partnering with media, offering both scientists and news outlets fresh ways to convey the story of Arctic change in an era of resource constraints.Innovative uses of crittercams, webcams, and satellite observations offer educators and interested citizens a way to track and appreciate Arctic change. But more can be done to engage the public directly without the news media as an intermediary, particularly if polar scientists or their institutions test some of the established practices honed by more experienced communicators at NASA.

  17. Vitiligo: A Possible Model of Degenerative Diseases

    Science.gov (United States)

    Bellei, Barbara; Pitisci, Angela; Ottaviani, Monica; Ludovici, Matteo; Cota, Carlo; Luzi, Fabiola; Dell'Anna, Maria Lucia; Picardo, Mauro

    2013-01-01

    Vitiligo is characterized by the progressive disappearance of pigment cells from skin and hair follicle. Several in vitro and in vivo studies show evidence of an altered redox status, suggesting that loss of cellular redox equilibrium might be the pathogenic mechanism in vitiligo. However, despite the numerous data supporting a pathogenic role of oxidative stress, there is still no consensus explanation underlying the oxidative stress-driven disappear of melanocytes from the epidermis. In this study, in vitro characterization of melanocytes cultures from non-lesional vitiligo skin revealed at the cellular level aberrant function of signal transduction pathways common with neurodegenerative diseases including modification of lipid metabolism, hyperactivation of mitogen-activated protein kinase (MAPK) and cAMP response element-binding protein (CREB), constitutive p53-dependent stress signal transduction cascades, and enhanced sensibility to pro-apoptotic stimuli. Notably, these long-term effects of subcytotoxic oxidative stress are also biomarkers of pre-senescent cellular phenotype. Consistent with this, vitiligo cells showed a significant increase in p16 that did not correlate with the chronological age of the donor. Moreover, vitiligo melanocytes produced many biologically active proteins among the senescence-associated secretory phenotype (SAPS), such as interleukin-6 (IL-6), matrix metallo proteinase-3 (MMP3), cyclooxygenase-2 (Cox-2), insulin-like growth factor-binding protein-3 and 7 (IGFBP3, IGFBP7). Together, these data argue for a complicated pathophysiologic puzzle underlying melanocytes degeneration resembling, from the biological point of view, neurodegenerative diseases. Our results suggest new possible targets for intervention that in combination with current therapies could correct melanocytes intrinsic defects. PMID:23555779

  18. Matching point clouds: limits and possibilities.

    Science.gov (United States)

    Rudolph, H; Quaas, S; Luthardt, R G

    2002-01-01

    In computer-aided production of fixed dental restorations, the process chain always starts with digitizing, independent of the type of further (data) processing, the material used, and the kind of restoration to be produced. The quality of the digitized data, followed by the influences of further data processing and the production parameters, decisively influence the fitting accuracy of the dental restoration to be fabricated. The accuracy with which individually measured 3D data sets in the form of point clouds can be matched for further processing in one common system of coordinates was the object of the present study. Casts of the maxilla and mandible were digitized in several partial measurements comprising two to three teeth in each case, using an optical three-coordinate measuring system. The individual segments were sequentially aligned to surfaces that were created on the basis of partial point clouds. The mean deviation between surfaces and point clouds was between 1.90 microns and 18.24 microns. The accuracy of the alignment was determined by the RMS (root mean square) error, and was on average 14.2 microns (SD 7 microns) for the maxilla and 17.2 microns (SD 9.4 microns) for the mandible. Combining a larger number of smaller segments did not improve the result, since the errors of the individual registrations are summed in sequential matching. In this study, the errors arising in matching are not negligible and can possibly negatively influence the quality (fitting accuracy) of the restoration produced on the basis of the matched data records.

  19. A Possibly Universal Red Chromophore for Jupiter

    Science.gov (United States)

    Sromovsky, Lawrence A.; Baines, Kevin; Fry, Patrick M.

    2016-10-01

    A new laboratory-generated chemical compound made from photodissociated ammonia (NH3) molecules reacting with acetylene (C2H2) was suggested as a possible coloring agent for Jupiter's Great Red Spot (GRS) by Carlson et al. (2016, Icarus 274, 106-115). Baines et al. (2016, AAS/DPS Meeting abstract) showed that the GRS spectrum measured by the visual channels of the Cassini VIMS instrument in 2000 could be accurately fit by a cloud model in which the chromophore appeared as small particles in a physically thin layer immediately above the main cloud layer of the GRS. Here we show that the same chromophore and similar layer structure can also provide close matches to the 0.4-1 micron spectra of many other cloud features on Jupiter, suggesting that this material may be a nearly universal chromophore responsible for the various degrees of red coloration on Jupiter. This is a robust conclusion, even for 12 percent changes in VIMS calibration and large uncertainties in the refractive index of the main cloud layer due to uncertain fractions of NH4SH and NH3 in its cloud particles. The chromophore layer can account for color variations among north and south equatorial belts, equatorial zone, and the Great Red Spot, by varying particle size from 0.12 to 0.29 micron and optical depth from 0.06 to 0.76. The total mass of the chromophore layer is much less variable than its optical depth, staying mainly within 6-10 micrograms/cm2 range, but is only about half that amount in the equatorial zone. We also found a depression of the ammonia volume mixing ratio in the two belt regions, which averaged 0.4-0.5 × 10-4 immediately below the ammonia condensation level, while the other regions averaged twice that value.LAS and PMF acknowledge support from NASA Grant NNX14AH40G.

  20. Is It Possible to Predict Strong Earthquakes?

    Science.gov (United States)

    Polyakov, Y. S.; Ryabinin, G. V.; Solovyeva, A. B.; Timashev, S. F.

    2015-07-01

    The possibility of earthquake prediction is one of the key open questions in modern geophysics. We propose an approach based on the analysis of common short-term candidate precursors (2 weeks to 3 months prior to strong earthquake) with the subsequent processing of brain activity signals generated in specific types of rats (kept in laboratory settings) who reportedly sense an impending earthquake a few days prior to the event. We illustrate the identification of short-term precursors using the groundwater sodium-ion concentration data in the time frame from 2010 to 2014 (a major earthquake occurred on 28 February 2013) recorded at two different sites in the southeastern part of the Kamchatka Peninsula, Russia. The candidate precursors are observed as synchronized peaks in the nonstationarity factors, introduced within the flicker-noise spectroscopy framework for signal processing, for the high-frequency component of both time series. These peaks correspond to the local reorganizations of the underlying geophysical system that are believed to precede strong earthquakes. The rodent brain activity signals are selected as potential "immediate" (up to 2 weeks) deterministic precursors because of the recent scientific reports confirming that rodents sense imminent earthquakes and the population-genetic model of K irshvink (Soc Am 90, 312-323, 2000) showing how a reliable genetic seismic escape response system may have developed over the period of several hundred million years in certain animals. The use of brain activity signals, such as electroencephalograms, in contrast to conventional abnormal animal behavior observations, enables one to apply the standard "input-sensor-response" approach to determine what input signals trigger specific seismic escape brain activity responses.

  1. Possible mechanisms of anosognosia of hemiplegia.

    Science.gov (United States)

    Heilman, Kenneth M

    2014-12-01

    Unawareness of hemiplegia was first called anosognosia by Babinski one century ago. This paper reviews some of the major theories that may account for this disorder. Weinstein and Kahn posited that anosognosia was a psychological defense mechanism; however, clinical as well as studies using transient hemispheric anesthesia reveal anosognosia for hemiplegia is more commonly associated with right than left hemisphere dysfunction, which is not entirely compatible with this denial hypothesis. Discovery is dependent on sensory feedback. Some patients with anosognosia will recognize their hemiparesis when their paretic hand is placed into ipsilesional hemispace suggesting that de-afferentation and inattention-neglect may be important mechanisms. Some patients with anosognosia have asomatognosia and hence being unaware that their paretic arm belongs to them they do not recognize that they have a deficit. Some patients have phantom movements and some may confabulate because they have a hemispheric disconnection. The feed-forward hypothesis posits that without an attempt to move, there is no expectation of movement and in the absence of arm movement there will be no discord that leads to discovery. Thus, motor neglect may be another cause of anosognosia. A defect in a theoretical comparator where expectations are compared to feedback may also be a cause of anosognosia, but further evidence is needed to support this postulate. Based on the studies of anosognosia for hemiplegia we have reviewed it appears that normal self-awareness depends on several modular systems. Further research of these possible mechanisms is needed to discern their relative importance and treatment. If these mechanisms do not fully account for anosognosia, investigators will need to develop and test new hypotheses.

  2. Sonification as a possible stroke rehabilitation strategy.

    Science.gov (United States)

    Scholz, Daniel S; Wu, Liming; Pirzer, Jonas; Schneider, Johann; Rollnik, Jens D; Großbach, Michael; Altenmüller, Eckart O

    2014-01-01

    Despite cerebral stroke being one of the main causes of acquired impairments of motor skills worldwide, well-established therapies to improve motor functions are sparse. Recently, attempts have been made to improve gross motor rehabilitation by mapping patient movements to sound, termed sonification. Sonification provides additional sensory input, supplementing impaired proprioception. However, to date no established sonification-supported rehabilitation protocol strategy exists. In order to examine and validate the effectiveness of sonification in stroke rehabilitation, we developed a computer program, termed "SonicPointer": Participants' computer mouse movements were sonified in real-time with complex tones. Tone characteristics were derived from an invisible parameter mapping, overlaid on the computer screen. The parameters were: tone pitch and tone brightness. One parameter varied along the x, the other along the y axis. The order of parameter assignment to axes was balanced in two blocks between subjects so that each participant performed under both conditions. Subjects were naive to the overlaid parameter mappings and its change between blocks. In each trial a target tone was presented and subjects were instructed to indicate its origin with respect to the overlaid parameter mappings on the screen as quickly and accurately as possible with a mouse click. Twenty-six elderly healthy participants were tested. Required time and two-dimensional accuracy were recorded. Trial duration times and learning curves were derived. We hypothesized that subjects performed in one of the two parameter-to-axis-mappings better, indicating the most natural sonification. Generally, subjects' localizing performance was better on the pitch axis as compared to the brightness axis. Furthermore, the learning curves were steepest when pitch was mapped onto the vertical and brightness onto the horizontal axis. This seems to be the optimal constellation for this two

  3. [Mobile IT: Possibilities and barriers of mHealth].

    Science.gov (United States)

    Böckmann, B

    2016-04-01

    The increasing availability of mobile devices and corresponding applications, both for providers and patients, often leads to speculation that mHealth, as the combination of mobile devices and health services is often called, would revolutionize the use of information technology (IT) in healthcare. On the other hand users, providers and operators providing such solutions are often confronted with completely new challenges. This article assesses the options and potential of mHealth and also takes a critical look at potential obstacles. As this field is very broad this critical analysis is illustrated by means of three exemplary application areas: mHealth in radiology, the influence of mHealth on research and mHealth as an enabler of new services, always with examples from other countries.The use of mHealth in radiology currently often develops empirically from existing applications in a relatively unstructured way and benefiting from the dynamic development of mobile technology. The possibilities range from viewing images at the bedside via mobile accessibility of radiologists up to teleradiology. In research there is a huge potential in solutions that actively involve patients with their own mobile devices but the field of data protection is still perceived in Germany as problematic so that only a few research institutions are actively addressing these options. The concept of mHealth allows physicians, hospitals and other service providers to invent entirely new services and a start-up scene is beginning to be established with business models becoming successful particularly with exchanges at the interface with established suppliers.

  4. A possible molecular metric for biological evolvability

    Indian Academy of Sciences (India)

    Aditya Mittal; B Jayaram

    2012-07-01

    Proteins manifest themselves as phenotypic traits, retained or lost in living systems via evolutionary pressures. Simply put, survival is essentially the ability of a living system to synthesize a functional protein that allows for a response to environmental perturbations (adaptation). Loss of functional proteins leads to extinction. Currently there are no universally applicable quantitative metrics at the molecular level for either measuring ‘evolvability’ of life or for assessing the conditions under which a living system would go extinct and why. In this work, we show emergence of the first such metric by utilizing the recently discovered stoichiometric margin of life for all known naturally occurring (and functional) proteins. The constraint of having well-defined stoichiometries of the 20 amino acids in naturally occurring protein sequences requires utilization of the full scope of degeneracy in the genetic code, i.e. usage of all codons coding for an amino acid, by only 11 of the 20 amino acids. This shows that the non-availability of individual codons for these 11 amino acids would disturb the fine stoichiometric balance resulting in non-functional proteins and hence extinction. Remarkably, these amino acids are found in close proximity of any given amino acid in the backbones of thousands of known crystal structures of folded proteins. On the other hand, stoichiometry of the remaining 9 amino acids, found to be farther/distal from any given amino acid in backbones of folded proteins, is maintained independent of the number of codons available to synthesize them, thereby providing some robustness and hence survivability.

  5. Pacifist empowerment for other possible worlds

    Directory of Open Access Journals (Sweden)

    Eduardo Sandoval Forero

    2015-12-01

    Full Text Available This article of analytical content, aims to interpret some significant elements considered for the analysis of pacifist empowerment. Starting from the theoretical and practical background that on empowerment generally presented in Latin America and in Mexico from the ideas of Paulo Freire, as well as the understandings of the concept have been exposed from the philosophical, participatory, gender, social, and development approaches. According to the purpose and object of research, the article falls within the qualitative methodology of hermeneutic type that allows us to identify, describe, analyze, and reflect on the pacifist empowerment, based on textual sources and Peace research categories, considering particular bibliography on the subject. The qualitative research approach was supplemented with the technique of observation and dialogue on the subject taught by Francisco Muñoz in his last journey to Mexico. In the first part the results of the development and empowerment of the term approaches and their application is described in general terms. The conventional concept is discussed to understand the similarities and differences with the pacifist empowerment. In the second part the approach of pacifist empowerment having as theoretical support for Peace studies and particularly Muñoz and his coauthors addressed approaches is discussed. Some understandings about the issue are outlined and the article concludes that the concept of pacifist empowerment is in theoretical construction from the perspective of peace studies, and his statement is proposed as a know-how transformer of the subject and collective action to decide and to influence structural, cultural, gender or any violence condition as a strategy of nonviolent social change to build more peaceful worlds.

  6. RESSOURCES ALLOCATION POSSIBILITIES WITHIN HEALTH SERVICES

    Directory of Open Access Journals (Sweden)

    Manea Liliana

    2011-12-01

    Full Text Available The state policy in the health care area must take into account the complexity and specificity of the domain. Health means not only “to treat”, but also “to prevent” and “to recover and rehabilitate the individual physically”. Regardless of the adopted health insurance system, the health system is facing a big problem and this is the insufficient funds necessary to function properly. The underfunding may have various causes, from a wrong health policy, based on “treating” instead of “preventing”, by the misuse of funds. This papers intended to formulate assumptions that underpin the research I am conducting within the Doctoral Research Program held at the Valahia University of Targoviste, which aims at using the management control in increasing the health services performance. The application of the accounting and management control methods in determining health costs can be a beginning to streamline the system. This is also a result of the fact that health care is a public service with specific characteristics: it can not be subject only to market requirements but at the same time he must undergo an administrative savings, representing a typical case of market failure. The increased cost of treatment, as well as the decline in their quality can be determined by the discrepancy between the funding and payment mechanisms. Different payment systems currently available do nothing but perpetuate the shortcomings in the system. Switching to the introduction of cost and budgets by cost centers or object (if solved can be a step forward for a better management of resources. In this context, we consider as a necessity to be imposed the cost analysis on responsibility centers, the definition of the cost object and cost center identification and determination of direct costs and those indirect services to choose the basis for the allocation of cost centers and the determination of each actual cost per diagnosis.

  7. Possible ways of space weather prediction improvement

    Science.gov (United States)

    Khabarova, O. V.

    2012-04-01

    Most popular short-term space weather prognoses are based on CME-like solar wind conditions' analysis. Short-term forecasts of severe magnetic storms using such a prognostic scheme are rather accurate, but sometimes are not actual due to too short alert time. Moreover, the number of severe storms is 10 times less than the weak magnetic storms' number. At the same time, the quality of weak and moderate magnetic storms forecast is poor for both short-term and medium-term prognoses, especially at a solar minimum. It is found that physical origin of weak and moderate magnetic storms is much closer to substorms' than to severe magnetic storms' nature; that is why CME-condition- based prognoses fail very often for mild geomagnetic storms [1]. Case studies and statistical analysis show that a mechanism of weak and moderate magnetic storms' development could be explained by excitation and compression of the magnetosphere by the SW density sharp increase in a combination with the southward-directed IMF. Sometimes there is a time delay up to several hours between the geoeffective density increase and the negative Bz IMF component's observation [1, 2]. The role of the solar wind velocity in the stimulation of the reconnection in the magnetotail is found out to be negligible for weak or moderate magnetic storms and essential for intensive and severe geomagnetic storms. So, a consideration of high-speed SW streams and the southward IMF direction as a main cause of a geomagnetic storm is correct for storms with Dstprediction. 1. Khabarova O.V., Current Problems of Magnetic Storm Prediction and Possible Ways of Their Solving. Sun and Geosphere, http://sg.shao.az/v2n1/SG_v2_No1_2007-pp-33-38.pdf , 2(1), pp. 33-38, 2007 2. Khabarova O., Pilipenko V., Engebretson M.J., and Rudenchik E., Solar wind and interplanetary magnetic field features before magnetic storm onset. ICS-8, University of Calgary Press, Canada, 127-132, 2006, http://ics8.ca/proc_files/khabarova.pdf .

  8. Energy possibilities from forest residues in the region of Castilla y Leon in Spain

    Energy Technology Data Exchange (ETDEWEB)

    Delgado, J.U. [Consejeria del Medio Ambiente y Ordenacion del Territorio, Valladolid (Spain). Direccion General del Medio Natural; Giraldo, G.A. [Valladolid Univ. (Spain). Dept. de Ingenieria Quimica

    1995-07-01

    This paper analyses the potential forest biomass existing in the autonomous region of Castilla y Leon in Spain. The presentation shows some possible applications for the use of forest biomass as fuel in previously adapted classic ovens. This study analyses the economic result of the application of forest biomass for fuel. A comparative economic study of the use of forest biomass and other traditional fuels demonstrates the profitability of such biomass as a source of complementary energy. (author)

  9. Metodología para elaborar leyes de posibilidad de retirada del cliente: una aplicación al sector del vestido // A Methodology to Elaborate Laws of Possibilities in the Retreat of a Client: An Application to the Dress Sector

    Directory of Open Access Journals (Sweden)

    Mauricio Ortigosa Hernández

    2016-12-01

    Full Text Available El presente documento pone a prueba en el sector del vestido en el centro del país, una metodología basada en la teoría de la incertidumbre y los subconjuntos borrosos para construir leyes de posibilidad de retirada del cliente con la empresa, con tan sólo la opinión subjetiva de expertos. La aportación del presente trabajo permite obtener un camino alternativo cuando no es posible contar con la información requerida por los modelos identificados en la literatura basados en principios derivados de las leyes del azar, incluso métodos heurísticos. Los resultados muestran la utilidad de los conceptos borrosos en un problema donde la incertidumbre en relación a la permanencia del cliente se hace evidente, permitiendo obtener un elemento necesario (tiempo, cuando se requiera medir el valor económico del cliente (Customer Lifetime Value: CLV en el campo de la incertidumbre. ------------------------------------ The current work tests, in the dress sector in the center of the country, a methodology based in the theory of uncertainty and the fuzzy subsets, in order to build laws of possibilities for the retreat of clients only with the subjective opinion given by experts. The contribution of the present work allows to obtain an alternative path when it is not possible to get the required information by the models identified in the literature based in principles derived of the random laws even from heuristic methods. The results show the utility of fuzzy concepts in a problem where the uncertainty in relation to the permanence of the client is evident and allows to obtain a valuable element (time, when the Customer Lifetime Value (CLV is required to be measured in the field of uncertainty.

  10. Microcomputer interfacing and applications

    CERN Document Server

    Mustafa, M A

    1990-01-01

    This is the applications guide to interfacing microcomputers. It offers practical non-mathematical solutions to interfacing problems in many applications including data acquisition and control. Emphasis is given to the definition of the objectives of the interface, then comparing possible solutions and producing the best interface for every situation. Dr Mustafa A Mustafa is a senior designer of control equipment and has written many technical articles and papers on the subject of computers and their application to control engineering.

  11. Fast-cycling superconducting synchrotrons and possible path to the future of US experimental high-energy particle physics

    Energy Technology Data Exchange (ETDEWEB)

    Piekarz, Henryk; /Fermilab

    2008-02-01

    The authors outline primary physics motivation, present proposed new arrangement for Fermilab accelerator complex, and then discuss possible long-range application of fast-cycling superconducting synchrotrons at Fermilab.

  12. Qualitative case study in pedagogical research: Cognitive possibilities and limitations

    Directory of Open Access Journals (Sweden)

    Ševkušić Slavica

    2008-01-01

    Full Text Available This paper discusses the cognitive possibilities and limitations of case study, as a qualitative research approach, and the fields of its application in studying pedagogical problems. Special attention is paid to different ways of defining and usual criticism pointed at this strategy in methodological literature of recent date: (1 general, theoretical (context independent knowledge is much more valuable from actual, practical (context dependent knowledge; (2 one cannot perform generalizations based on an individual case and therefore case study cannot contribute to the development of science; (3 case study is the most useful in generating hypotheses, that is, for the first phase of research process, while other methods are more suitable for testing hypotheses and building a theory; (4 case study tends to be partial towards verification, that is, the tendency of a researcher to confirm his/her previously established concepts; (5 it is often very difficult to present in brief the specific case study, and especially difficult to deduce general suggestions and theories on the basis of a specific case study. The objections, therefore, regard the possibility of theory development, reliability and validity of the approach, or doubt in its scientific status. The author of this paper discusses the justifiability of these objections and points out to different methodological procedures of arranging and analyzing the data collected for studying the case, which contribute to the reliability of this research approach. As a general conclusion, it is stated that the case method contains all the features relevant for studying pedagogical phenomena: preservation of the integrality of the phenomenon, appreciation of its context, developmental dimension and complementariness of different data sources.

  13. The intense pulsed light systems : new treatment possibilities for vascular, pigmented lesions and hair removal

    NARCIS (Netherlands)

    C.A. Schroeter (Careen)

    2004-01-01

    textabstractGiven all of the differences in between laser and IPLS devices and the need for additional information in IPLS treatment applications, the aim of this study was to evaluate new treatment possibilities using Intense Pulsed Light Sources and to address the following questions: 1. What are

  14. [Possibilities and results of "immunotherapy" in children with acute leucosis (author's transl)].

    Science.gov (United States)

    Blau, H J; Schulz, M

    1980-01-01

    In the introduction we are giving an overview about the possibilities of treatment of acute leucemias in childhood with an adjuvant immunotherapeutic component. Our own ten-years-experiences from 25 a. 1.1. children with BCG-application are useful for testing this kind of adjuvant therapy under clinical conditions in future, too.

  15. Strategic content in third sector organizations: possibilities and implications of social research in the field

    Directory of Open Access Journals (Sweden)

    Augusto Cesar Marins Machado

    2010-01-01

    Full Text Available The reflection on themes related to strategy, either in theoretical or empirical, has strong relationship with its applicability. However, this condition applied to Third Sector organizations emphasizes his preference for studies that avoid the application techniques and approaches developed on organizational studies. Thus, this paper seeks to promote the research possibilities and study of strategic content implications on third sector organizations such as reflection and contribution to the paradox presented above, with the following empirical possibilities: i. The possibilities present on interorganizational relations at strategic content framework and organizational outcomes; ii. The observation of strategic practices of organizations in this sector and their social network constitutions; and iii. The consequences of decisions at the strategic content to legitimize the actors social practices.

  16. Melatonin, a possible promising panacea for premature ovarian failure

    Directory of Open Access Journals (Sweden)

    Ting Guo

    2011-04-01

    Full Text Available Premature ovarian failure (POF is characterized by impairment of ovarian function unrelated to elevatedfollicle-stimulating hormone (FSH before the age of 40. The consequence of POF is severe and distinctive, presentingfrom infertility to symptoms caused by hormone deprivation. The mechanism of POF remains unclearand current treatments are therefore ineffective. Melatonin (N-acetyl-5-methoxytryptamine is a neuroendocrinalhormone chiefly secreted by the pineal body. Melatonin exerts extensive physiological and pharmacologicaleffects on the biological rhythm, oxidative stress, reproduction, autoimmune and tumourigenesis. However,current researches have not yet brought melatonin into the study of POF. In the present review, we have involvedstate-of-the-art research progress of melatonin in ovary with regard to oxidation, follicle formation and function,and ovarian autoimmune disorders since these aspects mainly dispose to POF development. The features thatmelatonin scavenges reactive oxygen species (ROS, directly and indirectly induces follicle maturation, ovulationand inhibits apoptosis, and modulates autoimmune derangements in the ovaries are highly indicative that melatonincan effect in combating POF. Also, in this respect we have discussed the possibility of applying melatoninin the treatment of POF and have listed evidence of studies in vitro and in vivo. Vacant research directions aresubsequently suggested and the future application of melatonin in POF treatment is prospected.

  17. Possible atomoxetine-induced vitiligo: a case report.

    Science.gov (United States)

    Bilgiç, Özlem; Bilgiç, Ayhan

    2015-09-01

    Vitiligo is a chronic skin disease characterized by the appearance of white depigmented lesion due to a loss of melanocytes. The etiopathogenesis of vitiligo is not clear, but according to the neural theory of vitiligo, the direct and indirect effects of monoamine neurotransmitters cause melanocyte destruction and various studies have supported this theory. Many drugs have been related to the development of vitiligo, and the melanocytotoxic effects of the some of these drugs are thought to be related due to their effects on the monoaminergic system. Furthermore, a recent article reported the development of a localized loss of pigmentation after the application of a methylphenidate patch in a patient with attention-deficit/hyperactivity disorder (ADHD). Atomoxetine is an inhibitor of norepinephrine reuptake sites and is a drug that has been used for the treatment of ADHD. Here, we present a school-aged child with ADHD who displayed a vitiligo lesion following the initiation of atomoxetine. We further discuss the possible impact of the ADHD drugs on the development of vitiligo.

  18. Is non-directive communication in genetic counseling possible?

    Science.gov (United States)

    Pennacchini, M; Pensieri, C

    2011-01-01

    In 2007, over 560,000 genetic tests were performed in Italy. However, only 70,154 genetic counseling sessions were conducted. Some say that non-directive counseling is necessary so that the patient understands the test results and the different options available and that the physician should not influence the patient's free choice. We need to clarify the meaning of non-directive consultation and if it is in fact possible. Each doctor has his own values and, in order to achieve the intended purpose, he will give information that, with his verbal, para-verbal and body language will guide the patient to one decision or another. Taking into account the axiom of effective communication "You can't NOT communicate", non-directive counseling is very difficult or even impossible. In genetic counseling, the knowledge that the patient receives of the correct diagnosis and related medical facts and of the applicable genetic considerations is basic to the entire process. Nonetheless, such knowledge in itself is not sufficient if it cannot be appropriately imparted to the interested person or persons. We think "persuasion" is not the right method, but instead "convince" meaning "co-win", "win together" may be the best approach to a problem of such great importance. The counselor will have achieved the desired goal with his patient if he is able to channel the emotion towards a mutually beneficial objective. The primary goal is not to persuade but to win-together (convince) with the patient and the unborn child.

  19. The SMILE fluxgate sensor: performance and possibilities of improvement.

    Science.gov (United States)

    Belyayev, S.; Ivchenko, N.; Korepanov, V.; Marusenkov, A.

    2009-04-01

    to the sensor core dimensions. Another advantage of the proposed technique is rather simple construction of coil windings. The experimental test bench and the results, which prove the effectiveness of the proposed solution, will be described too. Secondly, the analysis of the consumed power of the magnetometer components will be made. Basing on the improved design of the super low power analogue magnetometer LEMI-031 recently developed in LC ISR, the applicability of the novel engineering solutions for decreasing power consumption of both the sensor and some electronic blocks of the SMILE instrument will be considered. And finally the possibilities of the noise level decreasing of the sensor will be studied. The last issue is very important for successful using of the modified version of the SMILE instrument in the Global Electromagnetic Moon Surveyor (GEMS) payload for the Indian spacecraft Chandrayaan-II. Reference: 1. I. Arriaga, N. Ivchenko, G. Olsson, M. Alaniz, S. Belyayev, A. Marusenkov, SMILE - a miniaturized fluxgate magnetometer, Proc. 18th ESA Symposium on ‘Europian Rocket and Balloon Programmes and Related research', Visby, Sweden, 3-7 June 2007 (ESA SP-647, November 2007). 2. A. Forslund, S. Belyayev, N. Ivchenko, G. Olsson, T. Edberg, A. Marusenkov, Miniaturized digital fluxgate magnetometer for small spacecraft applications, Meas. Sci. Technol. 19 (2008) 015202 (10pp) 3. I. Arriaga, Numerical Modeling and Evaluation of the Small Magnetometer in Low-Mass Experiment (SMILE), Space and Plasma Physics Royal Institute of Technology, TRITA-EE 2007:048.

  20. Model investigations on the possibilities of restoring the ozon layer. Final report; Modelluntersuchungen zur Moeglichkeit der Restauration der Ozonschicht. Schlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Roeth, E.P.; Reinhardt, H.; Zellner, R.

    2001-02-01

    Proposals from the literature how to restore the stratospheric ozone layer had been investigated in respect to the possibility of application. All investigated proposals are not applicable. (orig.) [German] Vorschlaege zur Restauration der stratosphaerischen Ozonschicht in der Literatur wurden auf ihre Anwendungsmoeglichkeiten hin untersucht. Alle Vorschlaege, die untersucht wurden, sind nicht durchfuehrbar. (orig.)

  1. Possible future lakes in the Andes of Peru

    Science.gov (United States)

    Colonia, Daniel; Haeberli, Wilfried; Torres, Judith; Giraldez, Claudia; Schauwecker, Simone; Santiago, Alexzander; Cochachin, Alejo; Huggel, Christian

    2015-04-01

    Climate change has caused large losses of glacier mass in the Andes of Peru. Also, given the projected changes in climate, based on different IPCC scenarios for 2050 and 2080, simulations with a tropical glacier-climate model indicate that glaciers will continue to retreat. According to the national Peruvian glacier inventories 43% of glacier area has disappeared between 1970 and 2003-2010 in the 19 snowy mountain ranges and a total of 8 355 new lakes have formed in deglaciating terrain. With glacier retreat new lakes form in parts of the glacier tongue where there is an overdeepening, and these lakes can be a source of natural hazards to downstrean populations. Therefore, the identification of possible future lakes is important to plan for preventive measures concerning possible lake outbursts as well as to understand changes in freshwater storage in the corresponding source areas. Modeling of glacier-bed overdeepenings and possible future lakes forming in such topographic depressions when becoming ice-free was done using the SRTM DEM from the year 2000 with a 90 m resolution and the 2003-2010 glacier outlines from the recently published national glacier inventory of Perú. The GIS-based analysis followed three main steps: (1) identification of flat glacier areas with less than 10° surface slope as a first-order spatial approximation to possible occurrences of glacier-bed overdeepenings; (2) application, using Google Earth, of three morphological indications of glacier-bed overdeepenings following Frey et al. (2010): steepening surface slope, onset of crevasse formation, lateral flow-narrowing; and (3) verification of the results from steps (1) and (2) by comparison with GlabTop modeling of bed topographies following Linsbauer et al. (2012) using the SRTM DEM, contour lines and constructed branch lines for all glaciers. A pilot study has already been carried out for the Cordillera Blanca. The results show that 31 major new lakes may form in the future. The total

  2. Physics possibilities at India-based Neutrino Observatory

    Indian Academy of Sciences (India)

    S Uma Sankar; INO Collaboration

    2006-10-01

    In this talk I review the physics possible at India-based Neutrino Observatory (INO). I discuss the improvement in the precision of currently known quantities and the possibility measuring the presently unknown quantities.

  3. Worlds of Possibilities in Response to Literature, Film, and Life.

    Science.gov (United States)

    Cox, Carole; Many, Joyce E.

    1989-01-01

    Examines the interrelationships between cinematic and literary works in terms of possible responses, or the possible worlds created when children encounter and create literary discourse. Notes that these responses reflect previous encounters with literature, film, and life. (MM)

  4. Possibilities for a valorisation of geomorphologic research deliverables

    Science.gov (United States)

    Geilhausen, M.; Götz, J.; Otto, J.-C.; Schrott, L.

    2009-04-01

    Many geomorphological studies focus on fundamental research questions in large parts, although there are lots of applied fields like landslide hazard assessment or water framework directive. As fundamental research is a common property, their outcomes should be more "open" and accessible to the public. This means that scientists have to find new ways presenting their results and outcomes besides publishing in scientific journals. This paper shows possibilities for a valorisation of geomorphologic research deliverables using print as well as digital media. Geotrails explain remarkable and exciting landscape features using information boards and become more and more popular and important for tourism in many parts of the world. With the growing interest in environmental change and outdoor activities, print media like field guides reach an increasing number of people. Field guides and Geotrails can be coupled in order to arise awareness about geomorphological landforms and to deliver more specific information on the site beyond the information given on the boards in the field. As field guides are designed for the general public they can be used for educational purposes as well. Today, this information can also be found in the internet offering virtual trips through landscapes using dynamic maps. Here, server side GIS technologies (WebGIS) using standardised interfaces provide new possibilities to show geomorphic data to the public and to share them with the scientific community. Furthermore, data formats like XML or KML are powerful tools for data exchange and can be used in interactive data viewers like Google Earth. We will present the Geotrail "Geomorphologischer Lehrpfad am Fuße der Zugspitze. Das Reintal - Eine Wanderung durch Raum und Zeit" (Bavarian Alps, Germany). Additionally, three geomorphologic WebGIS applications (Geomorphologic map Turtmanntal, Permafrostmap of Austria, Geomorphologic maps of Germany) will exemplify how geomorphologic information and

  5. Generalization of the possible algebraic basis of q-triplets

    Science.gov (United States)

    Tsallis, Constantino

    2017-02-01

    The so called q-triplets were conjectured in 2004 [C. Tsallis, Physica A 340, 1 (2004)] and then found in nature in 2005 [L.F. Burlaga, A.F. Vinas, Physica A 356, 375 (2005)]. A relevant further step was achieved in 2005 [C. Tsallis, M. Gell-Mann, Y. Sato, PNAS 102, 15377 (2005)] when the possibility was advanced that they could reflect an entire infinite algebra based on combinations of the self-dual relations q → 2 - q (additive duality) and q → 1/q (multiplicative duality). The entire algebra collapses into the single fixed point q = 1, corresponding to the Boltzmann-Gibbs entropy and statistical mechanics. For q ≠ 1, an infinite set of indices q appears, corresponding in principle to an infinite number of physical properties of a given complex system describable in terms of the so called q-statistics. The basic idea that is put forward is that, for a given universality class of systems, a small number (typically one or two) of independent q indices exist, the infinite others being obtained from these few ones by simply using the relations of the algebra. The q-triplets appear to constitute a few central elements of the algebra. During the last decade, an impressive amount of q-triplets have been exhibited in analytical, computational, experimental and observational results in natural, artificial and social systems. Some of them do satisfy the available algebra constructed solely with the additive and multiplicative dualities, but some others seem to violate it. In the present work we generalize those two dualities with the hope that a wider set of systems can be handled within. The basis of the generalization is given by the selfdual relation q → qa(q) ≡ ((a+2)-aq) / (a-(a-2)q) (a ∈ R). We verify that qa(1) = 1, and that q2(q) = 2 - q and q0(q) = 1/q. To physically motivate this generalization, we briefly review illustrative applications of q-statistics, in order to exhibit possible candidates where the present generalized algebras could be useful.

  6. Possibilities of Preoperative Medical Models Made by 3D Printing or Additive Manufacturing.

    Science.gov (United States)

    Salmi, Mika

    2016-01-01

    Most of the 3D printing applications of preoperative models have been focused on dental and craniomaxillofacial area. The purpose of this paper is to demonstrate the possibilities in other application areas and give examples of the current possibilities. The approach was to communicate with the surgeons with different fields about their needs related preoperative models and try to produce preoperative models that satisfy those needs. Ten different kinds of examples of possibilities were selected to be shown in this paper and aspects related imaging, 3D model reconstruction, 3D modeling, and 3D printing were presented. Examples were heart, ankle, backbone, knee, and pelvis with different processes and materials. Software types required were Osirix, 3Data Expert, and Rhinoceros. Different 3D printing processes were binder jetting and material extrusion. This paper presents a wide range of possibilities related to 3D printing of preoperative models. Surgeons should be aware of the new possibilities and in most cases help from mechanical engineering side is needed.

  7. Possibilities of Preoperative Medical Models Made by 3D Printing or Additive Manufacturing

    Science.gov (United States)

    2016-01-01

    Most of the 3D printing applications of preoperative models have been focused on dental and craniomaxillofacial area. The purpose of this paper is to demonstrate the possibilities in other application areas and give examples of the current possibilities. The approach was to communicate with the surgeons with different fields about their needs related preoperative models and try to produce preoperative models that satisfy those needs. Ten different kinds of examples of possibilities were selected to be shown in this paper and aspects related imaging, 3D model reconstruction, 3D modeling, and 3D printing were presented. Examples were heart, ankle, backbone, knee, and pelvis with different processes and materials. Software types required were Osirix, 3Data Expert, and Rhinoceros. Different 3D printing processes were binder jetting and material extrusion. This paper presents a wide range of possibilities related to 3D printing of preoperative models. Surgeons should be aware of the new possibilities and in most cases help from mechanical engineering side is needed. PMID:27433470

  8. The possibilities of applying infrared lasers in otolaryngology

    Science.gov (United States)

    Kukwa, Andrzej; Tulibacki, Marek P.; Wojtowicz, Piotr; Oledzka, Iwona; Obarska, Agnieszka

    2003-10-01

    The authors present their many years of experience in the area of laryngological surgery with various types of solid lasers. In our clinical practice we use Nd-YAG, Ho-YAG and Er-YAG surgical lasers. There are many reasons for applying lasers, depending on medical conditions. One of the most frequent cases are the nasal polyps, where surgical treatment is aimed at curing the results. For this type the procedures there was applied Nd-YAG laser, which has shortened the period of treatment and extended the remission. We also use this laser for mucal tissue corrections of the nasal conchs through deep coagulation effect. The above mentioned laser is also useful for the preventative treatment of granulation stenosis by removal of granulation tissue from different sections of the upper way; from the nose to the trachea.Other laser procedures in the nasal area include coagulation of Kisselbach locus, bleeding in Rendu-Osler disease, separating adhesions of the nasal concha from the nasal septum, coagulation of septal bleeding polyps, angiomas of different location, small papillomae of throat and nose, and reduction of hypertrophy nasopharyngeal mucoosa in OSAS patients, and uvolo-palato-pharyngoplasty (UPPP). Neodymium laser is also used for the management of neoplastic diseases in palliative and radical (CA. basocellulare) treatment for the resection of the premalignant changes (papilloma, leukoplakia) and early neoplastic changes of throat and larynx. Keloplasty in the area of larynx and trachea is performed with the use of Ho-YAG laser, with shallow effect, regardless of the density of tissue, enabling coagulation of vascular vessels. It enables non-traumatic resections of bone structures, such as the wall of maxillary sinus, nasal spine, or conchoplasty; the mucal tissue and the frame. Recent clinical tests are examining the possibilities of Er-YAG laser application for crushing calculus in the salivary ducts. Using lasers in laryngology enables their extensive

  9. Possible States Theory and Human Destiny in the Cosmos

    Science.gov (United States)

    Thomson, Shelley; Brandenburg, John

    Possible States Theory posits a universe of unique objects and unique collections of interactions between them. The interactions are designated the possible states. The states include past, future and possible interactions. The theory concerns the propagation of change in the collections of possible states. Using a few simple assumptions, it becomes possible to generalize about the occurrence of change. The theory is consistent with quantum electrodynamics in a finite and discrete environment; however, in the possible states universe, an interaction does not cause alternative possibilities to disappear. The picture of the universe yielded by the theory differs from the conventional viewpoint in important ways. Past, future and possible states may interact with one another; interactions occur without reference to location in space-time. Given that all possibilities are present, the possible states universe is complete. Per Gšdel's incompleteness theorems, the universe cannot be unambiguously described as information. Many truths, some contradicting each other, can simultaneously exist. The human future already participates in the present, opening possibilities never previously envisaged. To imagine the future, therefore, is to quantum mechanically assemble it. Accordingly, humanity prepares its path to the stars by dreaming of it.

  10. Development status und future possibilities for martensitic creep resistant steels

    Energy Technology Data Exchange (ETDEWEB)

    Hald, J. [Technical Univ. Denmark, Lyngby (Denmark). Dept. of Mechanical Engineering

    2010-07-01

    In the last four decades new stronger modified 9%Cr martensitic creep resistant steels have been introduced in power plants, which has enabled increases in maximum achievable steam conditions from the previous 250 bar and 540-560 C up to the values of 300 bar and 600-620 C currently being introduced all over the world. In order to further increase the steam parameters of steel based power plants up to a target value of 650 C/325 bar it is necessary to double the creep strength of the martensitic steels. At the same time the resistance against steam oxidation must be improved by an increase of the chromium content in the steels from 9% to 12%. However, so far all attempts to make stronger 12%Cr steels have led to breakdowns in long-term creep strength. Significant progress has been achieved in the understanding of microstructure stability of the martensitic 9-12%Cr steels: Observed microstructure instabilities in 11-12%Cr steels are explained by Z-phase precipitation, which dissolves fine MN nitrides. Improved understanding of effects of B and N on long-term creep properties has formed the basis of a series of new stronger 9%Cr test alloys with improved creep strength. In parallel 9%Cr test steels with low C content show very promising behavior in long-term tests. However, the 9%Cr steels must be surface coated to protect against steam oxidation at high temperature applications above 620%C. A possibility to use fine Z-phases for strengthening of the martensitic steels has been identified, and this opens a new pathway for development of stable strong 12%Cr steels. There are still good prospects for the realization of a 325 bar / 650 C steam power plant all based on steel. (orig.)

  11. Portfolios: possibilities for addressing emergency medicine resident competencies.

    Science.gov (United States)

    O'Sullivan, Patricia; Greene, Constance

    2002-11-01

    Portfolios are an innovative approach to evaluate the competency of emergency medicine residents. Three key characteristics add to their attractiveness. First, portfolios draw from the resident's actual work. Second, they require self-reflection on the part of the resident. Third, they are inherently practice-based learning since residents must review and consider their practice in order to begin the portfolio. This paper illustrates five different applications of portfolios. First, portfolios are applied to evaluating specific competencies as part of the training of emergency physicians. While evaluating specific competencies, the portfolio captures aspects of the general competencies. Second, the article illustrates using portfolios as a way to address a specific residency review committee (RRC) requirement such as follow-ups. Third is a description of how portfolios can be used to evaluate resident conferences capturing the competency of practice-based learning and possibly other competencies such as medical knowledge and patient care. Fourth, the authors of the article designed a portfolio as a way to demonstrate clinical competence. Fifth, they elaborate as to how a continuous quality improvement project could be cast within the portfolio framework. They provide some guidance concerning issues to address when designing the portfolios. Portfolios are carefully structured and not haphazard collections of materials. Following criteria is important in maintaining the validity of the portfolio as well as contributing to reliability. The portfolios can enhance the relationship between faculty and residents since faculty will suggest cases, discuss anomalies, and interact with the residents around the portfolio. The authors believe that in general portfolios can cover many of the general competencies specified by the ACGME while still focusing on issues important to emergency medicine. The authors believe that portfolios provide an approach to evaluation commensurate

  12. Digital image watermarking: its formal model, fundamental properties and possible attacks

    Science.gov (United States)

    Nyeem, Hussain; Boles, Wageeh; Boyd, Colin

    2014-12-01

    While formal definitions and security proofs are well established in some fields like cryptography and steganography, they are not as evident in digital watermarking research. A systematic development of watermarking schemes is desirable, but at present, their development is usually informal, ad hoc, and omits the complete realization of application scenarios. This practice not only hinders the choice and use of a suitable scheme for a watermarking application, but also leads to debate about the state-of-the-art for different watermarking applications. With a view to the systematic development of watermarking schemes, we present a formal generic model for digital image watermarking. Considering possible inputs, outputs, and component functions, the initial construction of a basic watermarking model is developed further to incorporate the use of keys. On the basis of our proposed model, fundamental watermarking properties are defined and their importance exemplified for different image applications. We also define a set of possible attacks using our model showing different winning scenarios depending on the adversary capabilities. It is envisaged that with a proper consideration of watermarking properties and adversary actions in different image applications, use of the proposed model would allow a unified treatment of all practically meaningful variants of watermarking schemes.

  13. Application of ion beams in electronics

    Energy Technology Data Exchange (ETDEWEB)

    Rosinski, W.

    1981-01-01

    Application of ion beams to change surface layer properties of solids has been discussed. Examples and application possibilities in the range of semiconducting materials, magnetic and ceramic materials as well as in metalurgy have been described.

  14. PRACTICAL APPLICATION OF QUALITY TOOLS

    Directory of Open Access Journals (Sweden)

    Duško Pavletić

    2008-09-01

    Full Text Available The paper is dealing with one segment of broader research of universality an systematicness in application of seven basic quality tools (7QC tools, which is possible to use in different areas: power plant, process industry, government, health and tourism services. The aim of the paper was to show on practical examples that there is real possibility of application of 7QC tools. Furthermore, the research has to show to what extent are selected tools in usage and what reasons of avoiding their broader application are. The simple example of successful application of the quality tools are shown on selected company in process industry.

  15. Quantitative non-monotonic modeling of economic uncertainty by probability and possibility distributions

    DEFF Research Database (Denmark)

    Schjær-Jacobsen, Hans

    2012-01-01

    to the understanding of similarities and differences of the two approaches as well as practical applications. The probability approach offers a good framework for representation of randomness and variability. Once the probability distributions of uncertain parameters and their correlations are known the resulting...... uncertainty can be calculated. The possibility approach is particular well suited for representation of uncertainty of a non-statistical nature due to lack of knowledge and requires less information than the probability approach. Based on the kind of uncertainty and knowledge present, these aspects...... by probability distributions is readily done by means of Monte Carlo simulation. Calculation of non-monotonic functions of possibility distributions is done within the theoretical framework of fuzzy intervals, but straight forward application of fuzzy arithmetic in general results in overestimation of interval...

  16. Possibilities and limitations of rod-beam theories. [nonlinear distortion tensor and nonlinear stress tensors

    Science.gov (United States)

    Peterson, D.

    1979-01-01

    Rod-beam theories are founded on hypotheses such as Bernouilli's suggesting flat cross-sections under deformation. These assumptions, which make rod-beam theories possible, also limit the accuracy of their analysis. It is shown that from a certain order upward terms of geometrically nonlinear deformations contradict the rod-beam hypotheses. Consistent application of differential geometry calculus also reveals differences from existing rod theories of higher order. These differences are explained by simple examples.

  17. The "Internal Leak" as a possible cause in the pathogenesis of peptic ulcer.

    Science.gov (United States)

    Demling, L; Riemann, J F; Schmidt, H; Richter, K

    1981-06-01

    In cat gastric mucosa stimulated with histamine and damaged by direct application of acetylsalicylic acid, the fluorescent dye acridine orange may be found outside the parietal cell. Normally it is distributed throughout, or bound to the limiting membrane of, the vesicles in the parietal cell. The special properties of this cationic dye in an acid environment, support the hypothesis that a so-called "internal leak" may possibly play an important role in the pathogenesis of peptic ulcer.

  18. The possibilities of using essential oils as an active ingredients or preservatives in cosmetic products

    OpenAIRE

    2011-01-01

    An important trend in the development of the cosmetics industry is searching for new biologically active, natural compounds and preservative systems, which will find application in the natural cosmetics production. Natural cosmetics are of considerable interest nowadays and essential oils could be employed in theirs production. The huge potential of essential oils indicates the possibility of applying them in practice because of theirs antibacterial, antiseptic, antifungal, and antioxidant...

  19. Bibliometric Application of Markov Chains.

    Science.gov (United States)

    Pao, Miranda Lee; McCreery, Laurie

    1986-01-01

    A rudimentary description of Markov Chains is presented in order to introduce its use to describe and to predict authors' movements among subareas of the discipline of ethnomusicology. Other possible applications are suggested. (Author)

  20. A Possible 456-Day Optical Period of OQ 530

    Institute of Scientific and Technical Information of China (English)

    Yi Liu; Juan Li; Jun-Hui Fan

    2007-01-01

    The post-1994 observations of the blazar OQ 530 in optical BV RI bands,and radio observations at 22 GHz and 37 GHz were collected.The date compensated discrete Fourier transform (DCDFT) and CLEANest methods were used to search for possible periodicities.Two possible periods of 456±100 days and 258±29 days were found in the optical bands.The existence of possible correlations between the optical and radio emissions was investigated by means of discrete correlation function (DCF) analysis,and no significant correlation was found.Some possible mechanisms for the periodic variability are discussed.

  1. Possibility of Strategic Alliance from Competition:A Game Analysis

    Institute of Scientific and Technical Information of China (English)

    张树义; 陈彦茹

    2004-01-01

    The possibility for two competitive firms to form a strategic alliance was quantitatively analyzed with the game theory. The strategic alliance could be formed in an infinitely repeated game with complete information or a finitely repeated game with incomplete information. In the former situation, the discount ratio is important. If the discount ratio is large enough, alliance would be a possible solution. In the latter situation, the bigger the possibility of the rationality is, the more possible is for both firms to make strategic alliance.

  2. Thin phosphatidylcholine films as background surfaces with further possibilities of functionalization for biomedical applications

    NARCIS (Netherlands)

    Tauk, Lara; Thami, Thierry; Ferez, Lynda; Kocer, Armagan; Janot, Jean-Marc; Dejardin, Philippe

    2013-01-01

    Non-specific adsorption is a crucial problem in the biomedical field. To produce surfaces avoiding this phenomenon, we functionalized thin (7-180 nm) poly(methylhydrosiloxane) (PMHS) network films at room temperature (approximate to 20 degrees C) with phospholipids(PL)bearing a phosphorylcholine hea

  3. On the issue of the possible application of the mediation institution in tax disputes

    Directory of Open Access Journals (Sweden)

    Olga A. Abakumova

    2015-12-01

    Full Text Available Objective to justify the necessity to use mediation in tax disputes. Methods the research is based on the dialectic method of cognition of mediation institution as a sociolegal phenomenon in development. The methodology of the research is general scientific methods induction and deduction hypothesis generalization abstraction formalization analogy historical approach system approach system analysis modeling logicallinguistic method etc.. Results the benefits of mediation in tax disputes for both parties the state and the taxpayer were determined it is concluded that the use of mediation in tax disputes settlement is an effective means to prevent the increase of the number of court cases and as a consequence contributes to the quality of justice. For greater efficiency of settling cases arising from tax legal relations specific recommendations are proposed for the introduction of mediation the necessity is grounded to prepare its due normativelegal regulation. Scientific novelty the article considers the features of mediation institution functioning in the Russian Federation and new trends in the development of this institution. Practical significance the main provisions and conclusions of the article can be used in research and teaching in addressing issues of mediation. nbsp

  4. Estimation of quality of labour life of personnel: method and possibilities of its application

    OpenAIRE

    Kompaniets, V.

    2009-01-01

    An author offers of principle a new method of estimation of level of quality of labour life of personnel, which takes into account sotsiokulturniy approach. It is based on vision of necessities of man and realization of them in labour from point of christianity, on the basis of which mentality was formed of our peoples, its economic culture.

  5. Thin phosphatidylcholine films as background surfaces with further possibilities of functionalization for biomedical applications.

    Science.gov (United States)

    Tauk, Lara; Thami, Thierry; Ferez, Lynda; Kocer, Armagan; Janot, Jean-Marc; Déjardin, Philippe

    2013-01-01

    Non-specific adsorption is a crucial problem in the biomedical field. To produce surfaces avoiding this phenomenon, we functionalized thin (7-180 nm) poly(methylhydrosiloxane) (PMHS) network films at room temperature (≈20°C) with phospholipids (PL) bearing a phosphorylcholine head. Regardless of their mode of preparation (casting or immersion), all surfaces appeared to be very hydrophilic with a captive air-bubble contact angle stabilized around 40°. The thin films were protein-repellent in phosphate saline buffer pH 7.4 according to analysis by normal scanning confocal fluorescence. Neither was any adsorption or spreading of l-α-phosphatidylcholine liposomes on such films observed. In addition, amino functional groups could be easily attached to the surface remaining available for further functionalization.

  6. Prussian Blue-coated interdigitated array electrodes for possible analytical application

    NARCIS (Netherlands)

    Hartmann, M.; Grabner, E.W.; Bergveld, P.

    1991-01-01

    Thin films of iron(III) hexacyanoferrate(II) (Prussian Blue) were electrochemically deposited on interdigitated array (IDA) electrodes, yielding systems which can be considered as chemiresistors in sensing alkali metal ion concentrations in an adjacent electrolyte. This is due to the fact that the c

  7. Bypassing P-Glycoprotein Drug Efflux Mechanisms: Possible Applications in Pharmacoresistant Schizophrenia Therapy

    Directory of Open Access Journals (Sweden)

    Famida G. Hoosain

    2015-01-01

    Full Text Available The efficient noninvasive treatment of neurodegenerative disorders is often constrained by reduced permeation of therapeutic agents into the central nervous system (CNS. A vast majority of bioactive agents do not readily permeate into the brain tissue due to the existence of the blood-brain barrier (BBB and the associated P-glycoprotein efflux transporter. The overexpression of the MDR1 P-glycoprotein has been related to the occurrence of multidrug resistance in CNS diseases. Various research outputs have focused on overcoming the P-glycoprotein drug efflux transporter, which mainly involve its inhibition or bypassing mechanisms. Studies into neurodegenerative disorders have shown that the P-glycoprotein efflux transporter plays a vital role in the progression of schizophrenia, with a noted increase in P-glycoprotein function among schizophrenic patients, thereby reducing therapeutic outcomes. In this review, we address the hypothesis that methods employed in overcoming P-glycoprotein in cancer and other disease states at the level of the BBB and intestine may be applied to schizophrenia drug delivery system design to improve clinical efficiency of drug therapies. In addition, the current review explores polymers and drug delivery systems capable of P-gp inhibition and modulation.

  8. Environmental Risk Limits for several phosphate esters, with possible application as flame retardant

    NARCIS (Netherlands)

    Verbruggen EMJ; Rila JP; Traas TP; Posthuma-Doodeman CJAM; Posthumus R; SEC

    2006-01-01

    Voor een aantal fosfaatesters, die mogelijk als vlamvertrager gebruikt worden, zijn Maximaal Toelaatbaar Risiconiveaus (MTR), Verwaarloosbaar Risiconiveaus (VR) en Ernstig Risiconiveaus (EReco, Engelse afkorting SRCeco) afgeleid. Deze milieurisicogrenzen zijn afgeleid voor de compartimenten water,

  9. The possibility of distance methods application for snow dump sites monitoring

    Directory of Open Access Journals (Sweden)

    Pasko Olga

    2016-01-01

    Full Text Available In this article the results of remote sensing of the Earth for monitoring of four snow dump sites in Tomsk are described. Their compliance with permitted type of the territory use was evaluated. Earlier unknown time of the operation start was identified. The spatial-temporal variability of areas was defined. The temperature profiles of snow dump and background sites were analyzed. Use of remote sensing data allowed easy identification of snow dump sites creation time. The fact that the sites are located out of zones of permitted type of the territory use was revealed, that is violation of the law. For the first time the cartographic material was collected and showed that in the recent years their areas increased in average in 18%. The fore-cast for the nearest years was made. The article contains satellite images indicting the degradation of soil-vegetative cover of snow dumps. The reasons are contamination and overcooling of the soil in the beginning of vegetation period. The research results became the initial material for perfection of snow dumps territories management and will be applied in the work of environmental protecting service. Approaches proposed by authors may be used in solving similar problems in any region.

  10. Radiant Cooling for Closed-Loop Water Containment: Exploration of Possible Application in Dry Docks

    Science.gov (United States)

    2015-08-20

    TYPE 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER 6. AUTHOR(S) 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 9. SPONSORING/ MONITORING AGENCY...lengths from 300 to 3000 with diameters ranging from 10 to 24 all cooled a design load of 8 ° = 4. 44̅̅̅̅ above ambient ...water contains a higher concentration of copper and other metals and is at a higher temperature compared to ambient conditions; this is not a concern

  11. Non-ulcer dyspepsia associated with NSAID intake: possibility of antacid drugs application

    Directory of Open Access Journals (Sweden)

    A. E. Karateev

    2003-01-01

    Full Text Available Objective. To investigate the comparative efficacy of Magalphil 800 in NSAID-associated dyspepsia. Patients and methods. 30 pts with rheumatic diseases (RD receiving NSAIDs and having dyspeptic symptoms were included. Pts were divided into 2 groups: group 1 (n=20, 2 males, 18 females, mean age 51,7+12,3 yTs, 7 pts had single erosion of stomach, 1 - multiple erosions, 1 - ulcer of stomach; group 2 (n=10, 1 male. 9 females, mean age 46,2±14,6 yrs, 2 pts had single erosion of stomach. Concomitant therapies (corticosteroids, cytotoxics were approximately the same in both groups. Pts in Group 1 received one tablet of Magalphil 800 four times a day; pts in Group 2 were treated by ranitidine 150 mg bid. Therapy of RD was not changed during the study. Subjective complains were controlled after 2 weeks. Results. Complains related to dyspepsia disappeared in all pts of Group 1 and in 8 pts of Group 2 after 5,2±2,4 and 7,3±3,8 days of treatment respectively (p>0,05. Healing of ulcer in 1 and healing of erosions in 5 pnts was observed in Group 1. Conclusions. Magalphil 800 is effective in NSAID-associated dyspepsia and can be used for treatment of NSAID-induced gastropathy.

  12. Space-based Solar Power: Possible Defense Applications and Opportunities for NRL Contributions

    Science.gov (United States)

    2009-10-23

    converter, solid state driver, and TWT power amplifier). Widely deployed in military systems and space qualified . • GaN HEMT: 80 W, 60% efficiency...240-m rims rotate about this axis to track the Sun. The Mantech SRS reflectors are of space - qualified polyimide with 94% reflectivity and an NRL...0.1-0.3 65 - 75 Space qualified , relatively compact, moderately expensive Magnetron 0.5-5 75 - 85 Inexpensive, compact, phase controllable GaN SSPA

  13. HREM analysis of graphite-encapsulated metallic nanoparticles for possible medical applications

    Energy Technology Data Exchange (ETDEWEB)

    Sinclair, Robert, E-mail: bobsinc@stanford.edu [Department of Materials Science and Engineering, Stanford University, Stanford, CA 94305-4034 (United States); Li, He [Department of Materials Science and Engineering, Stanford University, Stanford, CA 94305-4034 (United States); Department of Chemistry, Stanford University, Stanford, CA 94305-4401 (United States); Madsen, Steven [Department of Materials Science and Engineering, Stanford University, Stanford, CA 94305-4034 (United States); Dai, Hongjie [Department of Chemistry, Stanford University, Stanford, CA 94305-4401 (United States)

    2013-11-15

    High resolution electron microscopy has been applied to study the structure of metallic nanoparticles. These have sparked considerable interest as contrast agents in the field of biological imaging, including in magnetic resonance imaging (MRI) and computed tomography (CT). Here, we describe a method of synthesizing sub-10 nm superparamagnetic metal and alloy nanoparticles by reduction of metallic salts. Annealing at 900° C in a methane/hydrogen environment forms a thin graphitic-carbon shell which is expected to improve stability, biocompatibility, and functionalization. Subsequent high resolution electron microscopy verifies graphitization and allows for crystallographic analysis. Most particles consist of single crystals in the phase predicted for the bulk material at the annealing temperature. Electron energy loss spectroscopy, energy dispersive X-ray spectroscopy and lattice constant measurements show large variation in composition for alloy nanoparticles from a single synthesis. The magnetization relaxation time (T{sub 2}) measurements demonstrate that Fe and AuFe nanoparticles compete with commercially available iron oxide MRI contrast agents. X-ray attenuation measurements of an AuFe alloy nanoparticle solution gave a relative radiodensity of 280 Hounsfield Units, demonstrating promise as a dual-purpose contrast agent in CT and MRI. Long term stability in an atmospheric environment was also tested, with no signs of corrosion or oxidation after several years of storage. - Highlights: • Fe, Co, Fe–Co and Au–Fe nanoparticles were made by annealing their salts in CH{sub 4}/H{sub 2}. • High resolution TEM has determined crystal structures and graphite layer thickness. • Particles can be superior to iron oxide particles currently in use for MRI contrast. • Particles can provide similar CT numbers to clinically used barium contrast agents. • The graphite encapsulated particles show no oxidation or corrosion in atmosphere.

  14. Possible Application of Biotechnology to the Development of Biological Agents by Potential Enemies

    Science.gov (United States)

    1987-06-01

    production stage. In the past, fermentation was restricted to the food industry (e.g., wine, beer, cheese ) or the pharmaceutical manufacturers for...release of dopamine [99], GAB A [100], arachidonate, and prolactin [101]. In cell culture with myocardial cells, 0.1-10 ng/ml maitotoxin caused an...Neuropcptide Y Oxytocin Pancreatic polypeptides Physalaemin Neurotension Pituitary peptides Proctolin Prolactin Secretin Somatomedin

  15. Generation of ROS mediated by mechanical waves (ultrasound) and its possible applications.

    Science.gov (United States)

    Duco, Walter; Grosso, Viviana; Zaccari, Daniel; Soltermann, Arnaldo T

    2016-10-15

    The thermal decomposition of 9,10 diphenylanthracene peroxide (DPAO2) generates DPA and a mix of triplet and singlet molecular oxygen. For DPAO2 the efficiency to produce singlet molecular oxygen is 0.35. On the other hand, it has shown that many thermal reactions can be carried out through the interaction of molecules with ultrasound. Ultrasound irradiation can create hydrodynamic stress (sonomechanical process), inertial cavitation (pyrolitic process) and long range effects mediated by radicals or ROS. Sonochemical reactions can be originated by pyrolytic like process, shock mechanical waves, thermal reactions and radical and ROS mediated reactions. Sonolysis of pure water can yield hydrogen or hydroxyl radicals and hydrogen peroxide (ROS). When DPAO2 in 1,4 dioxane solution is treated with 20 or 24kHz and different power intensity the production of molecular singlet oxygen is observed. Specific scavengers like tetracyclone (TC) are used to demonstrate it. The efficiency now is 0.85 showing that the sonochemical process is much more efficient that the thermal one. Another endoperoxide, artemisinin was also studied. Unlike the concept of photosensitizer of photodynamic therapy, in spite of large amount of reported results in literature, the term sonosensitizer and the sonosensitization process are not well defined. We define sonosensitized reaction as one in which a chemical species decompose as consequence of cavitation phenomena producing ROS or other radicals and some other target species does undergo a chemical reaction. The concept could be reach rapidly other peroxides which are now under experimental studies. For artemisinin, an important antimalarian and anticancer drug, was established that ultrasound irradiation increases the effectiveness of the treatment but without any explanation. We show that artemisinin is an endoperoxide and behaves as a sonosensitizer in the sense of our definition.

  16. Bayes estimates of Markov trends in possibly cointegrated series: an application to US consumption and income

    NARCIS (Netherlands)

    R. Paap (Richard); H.K. van Dijk (Herman)

    2002-01-01

    textabstractStylized facts show that average growth rates of US per capita consumption and income differ in recession and expansion periods. Since a linear combination of such series does not have to be a constant mean process, standard cointegration analysis between the variables to examine the per

  17. Possibilities and Determinants of Using Low-Cost Devices in Virtual Education Applications

    Science.gov (United States)

    Bun, Pawel Kazimierz; Wichniarek, Radoslaw; Górski, Filip; Grajewski, Damian; Zawadzki, Przemyslaw; Hamrol, Adam

    2017-01-01

    Virtual reality (VR) may be used as an innovative educational tool. However, in order to fully exploit its potential, it is essential to achieve the effect of immersion. To more completely submerge the user in a virtual environment, it is necessary to ensure that the user's actions are directly translated into the image generated by the…

  18. Possible application of urinary analysis to estimate dissolution of some man-made vitreous fibers.

    Science.gov (United States)

    Wastiaux, A; Blanchard, O; Honnons, S

    1994-10-01

    A preliminary study at the institut National de l'Environnement Industriel et des Risques (INERIS) examined the dissolution of three man-made vitreous fiber samples (glasswool, rockwool, glass microfibers: JM 100) after intraperitoneal injections in male Wistar rats. The chemical composition of the original fibers was determined by inductively coupled plasma spectrometry (ICP). The urine of the rats was collected at fixed times between day 1 and day 204, and the ICP was used to look for elements known to be present in the original fibers. At day 204, a piece of omentum was removed at autopsy, ashed and analyzed by energy dispersive X-ray analysis (EDXA) to identify the elements remaining in the fibers. Silicon and aluminium were retained in the fibers from all samples at day 204. Losses in calcium, sodium, magnesium, and sulfur were observed, but these elements were not studied in the urine samples because they are naturally present in relatively high concentrations in rat cells and biological fluids. Although there was a loss of zinc from the glass microfibers, no corresponding difference was observed between the zinc levels excreted by the treated animals and by the controls. Similarly, despite the loss of manganese from the rockwool fibers at day 204, none was detectable in the urine samples. Titanium, present at the 0.3% level in rockwool, was not detectable by EDXA at day 204, but small quantities were detected in the first 2 weeks in the urine samples of rats treated with rockwool.(ABSTRACT TRUNCATED AT 250 WORDS)

  19. [Service robots in elderly care. Possible application areas and current state of developments].

    Science.gov (United States)

    Graf, B; Heyer, T; Klein, B; Wallhoff, F

    2013-08-01

    The term "Service robotics" describes semi- or fully autonomous technical systems able to perform services useful to the well-being of humans. Service robots have the potential to support and disburden both persons in need of care as well as nursing care staff. In addition, they can be used in prevention and rehabilitation in order to reduce or avoid the need for help. Products currently available to support people in domestic environments are mainly cleaning or remote-controlled communication robots. Examples of current research activities are the (further) development of mobile robots as advanced communication assistants or the development of (semi) autonomous manipulation aids and multifunctional household assistants. Transport robots are commonly used in many hospitals. In nursing care facilities, the first evaluations have already been made. So-called emotional robots are now sold as products and can be used for therapeutic, occupational, or entertainment activities.

  20. Arsenic accumulating bacteria isolated from soil for possible application in bioremediation.

    Science.gov (United States)

    Majumder, Aparajita; Ghosh, Sagarmoy; Saha, Niharendu; Kole, S C; Sarkar, Supradip

    2013-09-01

    Twenty six arsenic (As) resistant bacterial strains were isolated from As contaminated paddy soil of West Bengal, India. Among them, 10 isolates exhibited higher As resistance capacity and could grow in concentration of 12000 mg I-1 of arsenate (AsV) and 2000 mg l-1 of arsenite (Aslll) in growing medium. Maximum growth was observed at 1000 mg I-1and 100 mg I-1 in case of AsV and Asll respectively. Results of incubation study carried out in basal salt minimal media (BSMY) containing 25 mg l-1 of AsV and Aslll separately showed that the isolates could accumulate 1.03 - 6.41 mg I-1 of AsV and 2.0 - 7.6 mg l-1 of Aslll from the media. The bacterial isolate AGH-21 showed highest As accumulating capacity both for AsV (25.64%) and Aslll (30.4%) under laboratory conditions. The isolates AGH-21 (NCBI accession no: HQ834295) showed highest sequence similarity (98%) with Bacillus sp. and could be used as a potential bioremediator in future to combat with arsenic toxicity.

  1. Application possibilities of several modern methods of microscopy and microanalysis in forensic science field

    Science.gov (United States)

    Kotrly, Marek; Turkova, Ivana

    2011-06-01

    The methods of optical and electron microscopy and microanalysis are the linchpin of forensic inorganic analysis. However, their capacity is limited as for the exact identification of pigments and colour layers, and therefore it is essential that they be complemented by other methods of phase microanalysis - powder X-ray microdiffraction (micro pXRD) and FTIR in transmission mode. The classic way of sample division for different methods is not suitable with regard to the inhomogeneity of the sequence of strata. That is why a method was tested that would allow performance of optical microscopy, SEM/EDS(WDS), micro pXRD and FTIR in a nondestructive manner, from an identical spot of a single fragment. The solution can be polished sections - embedded samples and microtome sections. Conductive zerobackground single-crystal silicon plates were developed and tested for sample fixation in SEM, micro pXRD and transmission FTIR. Methods using a focused ion beam - FIB have recently gained importance in the field of electron microscopy. In the forensic sphere they can be employed in examinations of metal materials, technical analyses of documents, post-blast and gunshot residues.

  2. Possibilities of the application of the inquiry-based science education at a country school

    OpenAIRE

    DAŇOVÁ, Dagmar

    2014-01-01

    This master thesis presents the results of the inquiry-based science education at a country school. It compares the current coverage teaching with inquiry-based teaching in theory and describes the process, levels, benefits and limitations of this pedagogical approach.

  3. Application of capillary hysteresis phenomenon for evaluation of recycling possibility of selected MMC

    Directory of Open Access Journals (Sweden)

    D. Nagolska

    2011-07-01

    Full Text Available Properties of composites made through saturation of ceramic reinforcement preforms with liquid metal are the cause of growing use of these materials. Taking increasing requirements regarding environment protection into consideration, already during design of such materials one should think of a way of their recycling at the end of life. The recycling of these materials is conducted by separation of components. Determining optimal superficial conditions of a recycling system: liquid metal matrix – reinforcement preform – medium enables automatic course of the recycling process, but does not guarantee high yield of metal. With identical superficial conditions of the recycling system and different structure of reinforcement preforms significant differences in metal yield can be obtained. Identification of a type of a capillary present in reinforcement preforms may allow to determine, already during stage of material design, which types of composites will undergo the recycling process better and for which types one has to accept decreased yield of matrix metal. This identification can be done on the basis of an analysis of results obtained during examination conducted with mercury porosimetry, comparing acquired hysteresis graphs with model graphs proposed by de Boer for adsorbent analysis. Considering the analysis of image of structure of examined reinforcement preforms makes the identification process easier and faster.

  4. Possibilities and Limitations of the Application of Academic Tutoring in Poland

    Science.gov (United States)

    Krajewska, Anna; Kowalczuk-Waledziak, Marta

    2014-01-01

    In the face of mass education, the need to seek individualized methods of students' teaching-learning is increasing. That causes academic tutoring to become more and more popular in higher education all over the world. The article presents the theoretical background of tutoring, the results of research in that regard and the benefits of its…

  5. Spectroscopic Interpretation of PAH-Spectra in Minerals and Its Possible Application to Soil Monitoring

    Directory of Open Access Journals (Sweden)

    Eun-Joung Ko

    2010-04-01

    Full Text Available In order to properly assess the feasibility of using Laser-Induced Fluorescence (LIF spectroscopy for soil monitoring, the variation of fluorescence intensity due to the heterogeneity and complexity of soil media was investigated. Different soil minerals showed fluorescence spectral structures distinguishable from the contaminants, implying dissimilar interactions or the binding of contaminants on mineral surfaces. More interestingly, solvent and water addition showed different responses in the fluorescence spectral structure showing their effect on the interactions between contaminants and minerals. These results support the claim that the spectral structure contains information on contaminant-mineral interactions; therefore contaminants can be used as a fluorescence probe for these interactions.

  6. On possibilities of application of Miller formula for determination of parameters of Micropixel Avalanche Photodiodes

    CERN Document Server

    Sadygov, Z; Akhmedov, G; Akhmedov, F; Mukhtarov, R; Sadygov, A; Titov, A; Zhezher, V

    2014-01-01

    Miller formula modified to take into account voltage drop on serial resistor of an avalanche photodiode is considered. It is proven by experimental data that modified Miller formula can describe operation of both regular and micropixel avalanche photodiodes with good enough precision. It is shown that operation parameters of the devices can be determined using a linear extrapolation of the voltage-current curve for both regular avalanche photodiode and the one operating in Geiger mode.

  7. Possible Nuclear Safeguards Applications: Workshop on Next-Generation Laser Compton Gamma Source

    Energy Technology Data Exchange (ETDEWEB)

    Durham, J. Matthew [Los Alamos National Lab. (LANL), Los Alamos, NM (United States). Physics Division

    2016-11-17

    These are a set of slides for the development of a next-generation photon source white paper. The following topics are covered in these slides: Nuclear Safeguards; The Nuclear Fuel Cycle; Precise isotopic determination via NRF; UF6 Enrichment Assay; and Non-Destructive Assay of Spent Nuclear Fuel. In summary: A way to non-destructively measure precise isotopics of ~kg and larger samples has multiple uses in nuclear safeguards; Ideally this is a compact, fieldable device that can be used by international inspectors. Must be rugged and reliable; A next-generation source can be used as a testing ground for these techniques as technology develops.

  8. The Seasonal KPSS Test: Examining Possible Applications with Monthly Data and Additional Deterministic Terms

    Directory of Open Access Journals (Sweden)

    Ghassen El Montasser

    2015-05-01

    Full Text Available The literature has been notably less definitive in distinguishing between finite sample studies of seasonal stationarity than in seasonal unit root tests. Although the use of seasonal stationarity and unit root tests is advised to determine correctly the most appropriate form of the trend in a seasonal time series, such a use is rarely noted in the relevant studies on this topic. Recently, the seasonal KPSS test, with a null hypothesis of no seasonal unit roots, and based on quarterly data, has been introduced in the literature. The asymptotic theory of the seasonal KPSS test depends on whether data have been filtered by a preliminary regression. More specifically, one may proceed to extracting deterministic components, such as the mean and trend, from the data before testing. In this paper, we examine the effects of de-trending on the properties of the seasonal KPSS test in finite samples. A sketch of the test’s limit theory is subsequently provided. Moreover, a Monte Carlo study is conducted to analyze the behavior of the test for a monthly time series. The focus on this time-frequency is significant because, as we mentioned above, it was introduced for quarterly data. Overall, the results indicated that the seasonal KPSS test preserved its good size and power properties. Furthermore, our results corroborate those reported elsewhere in the literature for conventional stationarity tests. These subsequent results assumed that the nonparametric corrections of residual variances may lead to better in-sample properties of the seasonal KPSS test. Next, the seasonal KPSS test is applied to a monthly series of the United States (US consumer price index. We were able to identify a number of seasonal unit roots in this time series. [1] [1]    Table 1 in this paper is copyrighted and initially published by JMASM in 2012, Volume 11, Issue 1, pp. 69–77, ISSN: 1538–9472, JMASM Inc., PO Box 48023, Oak Park, MI 48237, USA, ea@jmasm.com.

  9. Possible Economic Impacts of a Shutdown of the Thermohaline Circulation: an Application of FUND

    OpenAIRE

    P. Michael Link; Tol, Richard S J

    2004-01-01

    Climate change can lead to a substantial reduction of the strength of the thermohaline circulation in the world oceans. This is often thought to have severe consequences particularly on the North Atlantic region and Northern and Western Europe. The integrated assessment model FUND is used to estimate the extent of these impacts. The results indicate that, owing to a slower warming (rather than cooling) of the regions most affected by a thermohaline circulation collapse, climate change induced...

  10. Advances in the diagnosis of Ascaris suum infections in pigs and their possible applications in humans.

    Science.gov (United States)

    Vlaminck, Johnny; Levecke, Bruno; Vercruysse, Jozef; Geldhof, Peter

    2014-12-01

    Ascariasis is one of the most common parasitic diseases in both humans and pigs. It has been shown to cause growth deficits in both species and to impair cognitive development in children. Notwithstanding its substantial impact on pig economy and public health, diagnosis of ascariasis has mostly relied on the detection of eggs in stool and further development of novel, more sensitive methods has been limited or non-existent. Here, we discuss the currently available techniques for the diagnosis of ascariasis in pigs, their caveats, and the implications of a new serological detection technique for the evaluation of both pig and human ascariasis.

  11. Possible applications of RIA of LH and FSH in diagnosis of Stein-Leventhal syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Zenisek, L.; Talas, M.; Stehlikova, J.; Fingerova, H.; Duskova, M.

    1981-01-01

    LH determination in the serum significantly assists in diagnosing polycystic ovaries. Values exceeding 22 mIU/ml serum are indicative of a typical picture of polycystic ovaries similar to those found in the Stein-Leventhal syndrome. Lower levels indicate an atypical picture of polycystic ovaries or low-cyst ovary degeneration. FSH level cannot be used for this diagnosis.

  12. Electro-optical properties of dislocations in silicon and their possible application for light emitters

    Energy Technology Data Exchange (ETDEWEB)

    Arguirov, Tzanimir Vladimirov

    2007-10-14

    This thesis addresses the electro-optical properties of silicon, containing dislocations. The work demonstrates that dislocation specific radiation may provide a means for optical diagnostics of solar cell grade silicon. It provides insight into the mechanisms governing the dislocation recombination activity, their radiation, and how are they influenced by other defects present in silicon. We demonstrate that photoluminescence mapping is useful for monitoring the recombination activity in solar cell grade silicon and can be applied for identification of contaminants, based on their photoluminescence signatures. It is shown that the recombination at dislocations is strongly influenced by the presence of metals at the dislocation sites. The dislocation radiation activity correlates with their electrical activity. It is shown that the dislocation and band-to-band luminescence are essentially anti-correlated. {beta}FeSi{sub 2} precipitates, with a luminescence at 0.8 eV, were detected within the grains of block cast materials. They exhibit a characteristic feature of quantum dots, namely blinking. The second aspect of the thesis concerns the topic of silicon based light emitters for on-chip optical interconnects. The goal is an enhancement of sub-band-gap or band-to-band radiation by controlled formation of dislocation-rich areas in microelectronics-grade silicon as well as understanding of the processes governing such enhancement. For light emitters based on band-to-band emission it is shown, that internal quantum efficiency of nearly 2 % can be achieved, but the emission is essentially generated in the bulk of the wafer. On the other hand, light emitters utilizing the emission from dislocation-rich areas of a well localized wafer depth were explored. Three different methods for reproducible formation of a dislocation-rich region beneath the wafer surface were investigated and evaluated in view of their room temperature sub-band-gap radiation: (1) silicon implantation and annealing, (2) epitaxially grown SiGe buffer, and (3) direct wafer bonding. The most promising dislocation-based emitter appears the utilization of a dislocation network produced by wafer bonding. It is shown, that monochromatic D1 radiation (wavelength 1.5 {mu}m) can be generated in a well localised depth of the wafer. (orig.)

  13. Possible applications for fascial anatomy and fasciaology in traditional Chinese medicine.

    Science.gov (United States)

    Bai, Yu; Yuan, Lin; Soh, Kwang-Sup; Lee, Byung-Cheon; Huang, Yong; Wang, Chun-Lei; Wang, Jun; Wu, Jin-Peng; Dai, Jing-Xing; Palhalmi, Janos; Sha, Ou; Yew, David Tai Wai

    2010-06-01

    Research using medical imaging instruments such as computed tomography and magnetic resonance imaging has led to the proposal that the fascial network distributed over the human body is the anatomical basis for the acupoints and meridians of traditional Chinese medicine. Therefore, we put forward a new theory of anatomy called fascial anatomy. In fascial anatomy, a human body is divided into two major systems. One is the supporting-storing system of unspecialized connective tissues. The other is a functional system. An undifferentiated non-specific connective tissue network, with the participation of the nervous and the immune systems, constitutes the supporting-storing system of the human body. The various differentiated functional cells in the body that are supported and surrounded by the supporting-storing system constitute the functional system. The discipline that studies the supporting-storing system and the mutual relationship between this system and the functional system in a living human body is called fasciaology. The establishment of fascial anatomy and fasciaology opens a new research field in anatomy; consequently, fasciaology will play a significant role in biological medicine and traditional Chinese medical research, as well as future clinical practice.

  14. Application Possibilities of Social Marketing Technologies for Publicity of Electronic Government Services

    Directory of Open Access Journals (Sweden)

    Tadas Limba

    2013-08-01

    Full Text Available Nowadays e-government projects and projects in the public sector are changing the consistency and reality of our daily life and will need to be managed by project managers, who uge modern marketing tools and technologies. Social marketing is one of the modern marketing tools and, probably, it is the best tool to provide marketing in public sector project management, It has been changing in different ways since the founding of social marketing: the aim of social marketing, the technologies for using i ; but nowadays it’s hard to imagine public sector projects and, especially, egovernment projects, without using social marketing technologies. The usage of social marketing technologies can improve public sector project management and make the project more attractive to society or some part of it. This scientific paper represents social marketing transformation, the way in which social marketing needs to be used in the public sector project management process and analyses the phases of social marketing. It also gives some practical advics for public sector organizations o, how to implement social marketing in the e-government project deployment process.

  15. Possible Correlations of Multinational Military Operations and State Stability, and Application to State Building in Iraq

    Science.gov (United States)

    2009-03-01

    Egypt, 1882. U.S. Government Printing Office, Washington: 1883. Grey, Edward. “Sykes-Picot Agreement.” 1916. Hobbes , Thomas . Leviathan ...Thesis Advisors: Thomas Johnson Abbas Kadhim THIS PAGE INTENTIONALLY LEFT BLANK i REPORT...SUB-SAHARAN AFRICA) from the NAVAL POSTGRADUATE SCHOOL MARCH 2009 Author: Nicholas J. Buls Approved by: Professor Thomas

  16. Measuring of foot plantar pressure—possible applications in quantitative analysis of human body mobility

    Science.gov (United States)

    Klimiec, E.; Jasiewicz, B.; Piekarski, J.; Zaraska, K.; Guzdek, P.; Kołaszczyński, G.

    2017-04-01

    The paper presents an evaluation of human mobility by gait analysis, carried out in natural conditions (outside of the laboratory). Foot plantar pressure is measured using a shoe insole with 8 sensors placed in different anatomical zones of the foot, and placed inside a sports shoe. Polarized polyvinylidene fluoride (PVDF) foil is used as a sensor material. A wireless transmission system is used to transmit voltage values to the computer. Miniaturization was the priority during the design of the system. Due to the linear relationship between force and transducer voltage, energy and power released during walking in arbitrary units can be calculated as an integral of the square of the transducer voltage over time. Gait measurements were carried out over several days on healthy persons during normal walking and slow walking. The performed measurements allowed for the determination of walking speed (number of steps per second), gait rhythm and manner of walking (applying force to inside versus outside part of the sole). It was found that switching from normal to slow walk increases gait energy by 25% while the pressure distribution across the anatomical regions of the foot remains unchanged. The results will be used to develop a programme for the evaluation of patients with orthopedic diseases or even with cardiac failures, for an estimation of the results of health recovery and training efficiency in many sports activities.

  17. X-ray dark field imaging of human articular cartilage: Possible clinical application to orthopedic surgery

    Energy Technology Data Exchange (ETDEWEB)

    Kunisada, Toshiyuki [Department of Medical Materials for Musculoskeletal Reconstruction, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558 (Japan); Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558 (Japan)], E-mail: toshi-kunisada@umin.ac.jp; Shimao, Daisuke [Department of Radiological Sciences, Ibaraki Prefectural University of Health Sciences, Ibaraki 300-2394 (Japan); Sugiyama, Hiroshi [Photon Factory, Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Ibaraki 305-0801 (Japan); Takeda, Ken; Ozaki, Toshifumi [Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558 (Japan); Ando, Masami [Research Institute for Science and Technology, Tokyo University of Science, Chiba 278-8510 (Japan)

    2008-12-15

    Despite its convenience and non-invasiveness on daily clinical use, standard X-ray radiography cannot show articular cartilage. We developed a novel type of X-ray dark field imaging (DFI), which forms images only by a refracted beam with very low background illumination. We examined a disarticulated distal femur and a shoulder joint with surrounding soft tissue and skin, both excised from a human cadaver at the BL20B2 synchrotron beamline at SPring-8. The field was 90 mm wide and 90 mm high. Articular cartilage of the disarticulated distal femur was obvious on DFI, but not on standard X-ray images. Furthermore, DFI allowed visualization in situ of articular cartilage of the shoulder while covered with soft tissue and skin. The gross appearance of the articular cartilage on the dissected section of the proximal humerus was identical to the cartilage shown on the DFI image. These results suggested that DFI could provide a clinically accurate method of assessing articular cartilage. Hence, DFI would be a useful imaging tool for diagnosing joint disease such as osteoarthritis.

  18. Aβ-binding molecules: Possible application as imaging probes and as anti-aggregation agents

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    As amyloid β (Aβ) is at the centre of pathogenesis of Alzheimer’s disease (AD), Aβ aggregate-specific probes for in vivo studies of Aβ are potentially important for the early diagnosis and the assessment of new treatment strategies in the AD brain by noninvasive imaging. Several series of compounds derived from Congo red (CR) and Thioflavin T (ThT) have been evaluated as potential probes for the Aβ imaging. They include a diversity of core structures contributing to their affinities to Aβ. Small-molecule inhibi- tors were known to inhibit the formation of Aβ oligomers and fibrils. This inhibition has to be performed in such a way that these inhibitors bind to Aβ in the binding channel where Aβ-binding probes should sit. Therefore, several of them were used as novel core structures to develop Aβ probes, with their de- rivatives exhibiting good Aβ affinities. This approach will facilitate the design of a variety of candidates for Aβ probe molecules and anti-aggregation-therapeutic drugs. Moreover, the finding of Aβ probes with diverse core structures recognized by binding sites on Aβs will likely provide a promising per- spective for the design of 99mTc-labeled probe-derived molecules.

  19. Screening and identification of polyhydroxyalkanoates producing bacteria and biochemical characterization of their possible application.

    Science.gov (United States)

    Sangkharak, Kanokphorn; Prasertsan, Poonsuk

    2012-01-01

    Polyhydroxyalkanoates (PHAs) accumulating bacteria were isolated under various selective conditions such as pH, salt concentrations and types of heavy metal. Fifty strains of bacterial isolates were found to belong to Bacillus, Proteus, Pseudomonas, Aeromonas, Alcaligenes and Chromobacterium, based on phenotypical features and genotypic investigation. Only twenty five bacterial isolates were selected and observed for the production of PHAs. Interestingly, bacteria belonging to Firmucutes Bacillus sp. produced a high amount of PHAs. The maximum PHAs were accumulated by B. licheniformis PHA 007 at 68.80% of dry cell weight (DCW). Pseudomonas sp., Aeromonas sp., Alcaligenes sp. and Chromobacterium sp. were recorded to produce a moderate amount of PHAs, varying from 10.00-44.32% of DCW. The enzymatic activity was preliminarily analyzed by the ratio of the clear zone diameter to colony diameter. Bacillus gave the highest ratio of hydrolysis zone which corresponds to the highest hydrolytic enzyme activities. Bacillus licheniformis PHA 007 had the highest lipase and protease activity at 2.1 and 5.1, respectively. However, the highest amylase activity was observed in Bacillus sp. PHA 023 at 1.4. Determination of metabolic characteristics was also investigated to check for their ability to consume a wide range of substrates. Bacillus, Aeromonas sp. and Alcaligenes sp. had great ability to utilize a variety of substrates. To decrease high PHA cost, different sources of cheap substrates were tested for the production of PHAs. Bacillus cereus PHA 008 gave the maximal yield of PHA production (64.09% of DCW) when cultivated in anaerobically treated POME. In addition, the accumulation of PHA copolymers such as 3-hydroxyvalerate and 3-hydroxyhexanoate was also observed in Bacillus and Pseudomomas sp. strain 012 and 045, respectively. Eight of the nine isolates accumulated a significant amount of PHAs when inexpensive carbon sources were used as substrates. Here it varied from 1.69% of DCW by B. licheniformis PHA 007 to 64.09% of DCW by B. cereus PHA 008.

  20. Detecting nuisance species using NGST: Methodology shortcomings and possible application in ballast water monitoring.

    Science.gov (United States)

    Zaiko, Anastasija; Martinez, Jose L; Ardura, Alba; Clusa, Laura; Borrell, Yaisel J; Samuiloviene, Aurelija; Roca, Agustín; Garcia-Vazquez, Eva

    2015-12-01

    Detecting the presence of potential invasive species in ballast water is a priority for preventing their spread into new environments. Next generation sequencing technologies are being increasingly used for exploring and assessing biodiversity from environmental samples. Here we apply high throughput sequencing from DNA extracted from ballast water (BW) samples employing two different platforms, Ion Torrent and 454, and compare the putative species catalogues from the resulting Operational Taxonomic Units (OTU). Water samples were taken from the RV Polastern ballast tank in five different days between the second and the twentieth navigation day. Pronounced decrease of oxygen concentration and increase of temperature occurred in the BW during this time, coincident with a progressively higher proportion of unassigned OTU and short reads indicating DNA degradation. Discrepancy between platforms for species catalogues was consistent with previously published bias in AT-rich sequences for Ion Torrent platform. Some putative species detected from the two platforms increased in frequency during the Polarstern travel, which suggests they were alive and therefore tolerant to adverse conditions. OTU assigned to the highly invasive red alga Polysiphonia have been detected at low but increasing frequency from the two platforms. Although in this moment NGST could not replace current methods of sampling, sorting and individual taxonomic identification of BW biota, it has potential as an exploratory methodology especially for detecting scarce species.