WorldWideScience

Sample records for application detecting point

  1. Applications of hand feature points detection and localization algorithms

    OpenAIRE

    Grzejszczak Tomasz; Niezabitowski Michał

    2016-01-01

    Growing interest in hand gesture recognition system, bring new possibilities in developing new ways of intuitive control. Controlling the everyday surrounding can be much easier with use of natural body language. This article presents the review of hand gestures systems basing on color images, focusing on hand feature points detection. Additionally, the ways of hand feature points control possibilities are discussed, along with possible examples of hand gestures control. Hand gestures are int...

  2. Point processes in forestry : an application to tree crown detection

    OpenAIRE

    Perrin, Guillaume; Descombes, Xavier; Zerubia, Josiane

    2006-01-01

    In this research report, we aim at extracting tree crowns from remotely sensed images using marked point processes of discs and ellipses. Our approach is indeed to consider that the data are some realizations of a marked point process. Once a geometrical object is defined, we sample a marked point process defined by a density with a Reversible Jump Markov Chain Monte Carlo dynamics and simulated annealing to get the maximum a posteriori estimator of the tree crown distribution on the image. I...

  3. Nearly Optimal Change-Point Detection with an Application to Cybersecurity

    CERN Document Server

    Polunchenko, Aleksey S; Mukhopadhyay, Nitis

    2012-01-01

    We address the sequential change-point detection problem for the Gaussian model where baseline distribution is Gaussian with variance \\sigma^2 and mean \\mu such that \\sigma^2=a\\mu, where a>0 is a known constant; the change is in \\mu from one known value to another. First, we carry out a comparative performance analysis of four detection procedures: the CUSUM procedure, the Shiryaev-Roberts (SR) procedure, and two its modifications - the Shiryaev-Roberts-Pollak and Shiryaev-Roberts-r procedures. The performance is benchmarked via Pollak's maximal average delay to detection and Shiryaev's stationary average delay to detection, each subject to a fixed average run length to false alarm. The analysis shows that in practically interesting cases the accuracy of asymptotic approximations is "reasonable" to "excellent". We also consider an application of change-point detection to cybersecurity - for rapid anomaly detection in computer networks. Using real network data we show that statistically traffic's intensity can...

  4. Detection of Geometric Keypoints and its Application to Point Cloud Coarse Registration

    Science.gov (United States)

    Bueno, M.; Martínez-Sánchez, J.; González-Jorge, H.; Lorenzo, H.

    2016-06-01

    Acquisition of large scale scenes, frequently, involves the storage of large amount of data, and also, the placement of several scan positions to obtain a complete object. This leads to a situation with a different coordinate system in each scan position. Thus, a preprocessing of it to obtain a common reference frame is usually needed before analysing it. Automatic point cloud registration without locating artificial markers is a challenging field of study. The registration of millions or billions of points is a demanding task. Subsampling the original data usually solves the situation, at the cost of reducing the precision of the final registration. In this work, a study of the subsampling via the detection of keypoints and its capability to apply in coarse alignment is performed. The keypoints obtained are based on geometric features of each individual point, and are extracted using the Difference of Gaussians approach over 3D data. The descriptors include features as eigenentropy, change of curvature and planarity. Experiments demonstrate that the coarse alignment, obtained through these keypoints outperforms the coarse registration root mean squared error of an operator by 3 - 5 cm. The applicability of these keypoints is tested and verified in five different case studies.

  5. 3D Interest Point Detection using Local Surface Characteristics with Application in Action Recognition

    DEFF Research Database (Denmark)

    Holte, Michael Boelstoft

    2014-01-01

    In this paper we address the problem of detecting 3D inter- est points (IPs) using local surface characteristics. We con- tribute to this field by introducing a novel approach for detec- tion of 3D IPs directly on a surface mesh without any require- ments of additional image/video information. The...... proposed Difference-of-Normals (DoN) 3D IP detector operates on the surface mesh, and evaluates the surface structure (curvature) locally (per vertex) in the mesh data. We present an exam- ple of application in action recognition from a sequence of 3-dimensional geometrical data, where local 3D motion de......- scriptors, Histogram of Optical 3D Flow (HOF3D), are ex- tracted from estimated 3D optical flow in the neighborhood of each IP and made view-invariant. Experiments on the pub- licly available i3DPost dataset show promising results....

  6. Reducing sojourn points from recurrence plots to improve transition detection: Application to fetal heart rate transitions.

    Science.gov (United States)

    Zaylaa, Amira; Charara, Jamal; Girault, Jean-Marc

    2015-08-01

    The analysis of biomedical signals demonstrating complexity through recurrence plots is challenging. Quantification of recurrences is often biased by sojourn points that hide dynamic transitions. To overcome this problem, time series have previously been embedded at high dimensions. However, no one has quantified the elimination of sojourn points and rate of detection, nor the enhancement of transition detection has been investigated. This paper reports our on-going efforts to improve the detection of dynamic transitions from logistic maps and fetal hearts by reducing sojourn points. Three signal-based recurrence plots were developed, i.e. embedded with specific settings, derivative-based and m-time pattern. Determinism, cross-determinism and percentage of reduced sojourn points were computed to detect transitions. For logistic maps, an increase of 50% and 34.3% in sensitivity of detection over alternatives was achieved by m-time pattern and embedded recurrence plots with specific settings, respectively, and with a 100% specificity. For fetal heart rates, embedded recurrence plots with specific settings provided the best performance, followed by derivative-based recurrence plot, then unembedded recurrence plot using the determinism parameter. The relative errors between healthy and distressed fetuses were 153%, 95% and 91%. More than 50% of sojourn points were eliminated, allowing better detection of heart transitions triggered by gaseous exchange factors. This could be significant in improving the diagnosis of fetal state. PMID:25308517

  7. Algorithms for Collision Detection Between a Point and a Moving Polygon, with Applications to Aircraft Weather Avoidance

    Science.gov (United States)

    Narkawicz, Anthony; Hagen, George

    2016-01-01

    This paper proposes mathematical definitions of functions that can be used to detect future collisions between a point and a moving polygon. The intended application is weather avoidance, where the given point represents an aircraft and bounding polygons are chosen to model regions with bad weather. Other applications could possibly include avoiding other moving obstacles. The motivation for the functions presented here is safety, and therefore they have been proved to be mathematically correct. The functions are being developed for inclusion in NASA's Stratway software tool, which allows low-fidelity air traffic management concepts to be easily prototyped and quickly tested.

  8. Detection of change points in underlying earthquake rates, with application to global mega-earthquakes

    Science.gov (United States)

    Touati, Sarah; Naylor, Mark; Main, Ian

    2016-02-01

    The recent spate of mega-earthquakes since 2004 has led to speculation of an underlying change in the global `background' rate of large events. At a regional scale, detecting changes in background rate is also an important practical problem for operational forecasting and risk calculation, for example due to volcanic processes, seismicity induced by fluid injection or withdrawal, or due to redistribution of Coulomb stress after natural large events. Here we examine the general problem of detecting changes in background rate in earthquake catalogues with and without correlated events, for the first time using the Bayes factor as a discriminant for models of varying complexity. First we use synthetic Poisson (purely random) and Epidemic-Type Aftershock Sequence (ETAS) models (which also allow for earthquake triggering) to test the effectiveness of many standard methods of addressing this question. These fall into two classes: those that evaluate the relative likelihood of different models, for example using Information Criteria or the Bayes Factor; and those that evaluate the probability of the observations (including extreme events or clusters of events) under a single null hypothesis, for example by applying the Kolmogorov-Smirnov and `runs' tests, and a variety of Z-score tests. The results demonstrate that the effectiveness among these tests varies widely. Information Criteria worked at least as well as the more computationally expensive Bayes factor method, and the Kolmogorov-Smirnov and runs tests proved to be the relatively ineffective in reliably detecting a change point. We then apply the methods tested to events at different thresholds above magnitude M ≥ 7 in the global earthquake catalogue since 1918, after first declustering the catalogue. This is most effectively done by removing likely correlated events using a much lower magnitude threshold (M ≥ 5), where triggering is much more obvious. We find no strong evidence that the background rate of large

  9. Detection of Change--Points in the Spectral Density. With Applications to ECG Data

    OpenAIRE

    Bertrand, Pierre; Teyssière, Gilles; Boudet, Gil; Chamoux, Alain

    2008-01-01

    proceeding of the workshop 'Fouille de données temporelles et analyse de flux de données' EGC'2009, january 27, Strasbourg, France We propose a new method for estimating the change-points of heart rate in the orthosympathetic and parasympathetic bands, based on the wavelet transform in the complex domain and the study of the change-points in the moments of the modulus of these wavelet transforms. We observe change-points in the distribution for both bands.

  10. Fingerprint Reference-Point Detection

    OpenAIRE

    Liu Manhua; Jiang Xudong; Kot Alex Chichung

    2005-01-01

    A robust fingerprint recognition algorithm should tolerate the rotation and translation of the fingerprint image. One popular solution is to consistently detect a unique reference point and compute a unique reference orientation for translational and rotational alignment. This paper develops an effective algorithm to locate a reference point and compute the corresponding reference orientation consistently and accurately for all types of fingerprints. To compute the reliable orientation field...

  11. Kernel change-point detection

    CERN Document Server

    Arlot, Sylvain; Harchaoui, Zaid

    2012-01-01

    We tackle the change-point problem with data belonging to a general set. We propose a penalty for choosing the number of change-points in the kernel-based method of Harchaoui and Capp\\'e (2007). This penalty generalizes the one proposed for one dimensional signals by Lebarbier (2005). We prove it satisfies a non-asymptotic oracle inequality by showing a new concentration result in Hilbert spaces. Experiments on synthetic and real data illustrate the accuracy of our method, showing it can detect changes in the whole distribution of data, even when the mean and variance are constant. Our algorithm can also deal with data of complex nature, such as the GIST descriptors which are commonly used for video temporal segmentation.

  12. Detecting corner points from digital curves

    International Nuclear Information System (INIS)

    Corners in digital images give important clues for shape representation, recognition, and analysis. Since dominant information regarding shape is usually available at the corners, they provide important features for various real life applications in the disciplines like computer vision, pattern recognition, computer graphics. Corners are the robust features in the sense that they provide important information regarding objects under translation, rotation and scale change. They are also important from the view point of understanding human perception of objects. They play crucial role in decomposing or describing the digital curves. They are also used in scale space theory, image representation, stereo vision, motion tracking, image matching, building mosaics and font designing systems. If the corner points are identified properly, a shape can be represented in an efficient and compact way with sufficient accuracy. Corner detection schemes, based on their applications, can be broadly divided into two categories: binary (suitable for binary images) and gray level (suitable for gray level images). Corner detection approaches for binary images usually involve segmenting the image into regions and extracting boundaries from those regions that contain them. The techniques for gray level images can be categorized into two classes: (a) Template based and (b) gradient based. The template based techniques utilize correlation between a sub-image and a template of a given angle. A corner point is selected by finding the maximum of the correlation output. Gradient based techniques require computing curvature of an edge that passes through a neighborhood in a gray level image. Many corner detection algorithms have been proposed in the literature which can be broadly divided into two parts. One is to detect corner points from grayscale images and other relates to boundary based corner detection. This contribution mainly deals with techniques adopted for later approach

  13. End-Point Detection With Laser Interferometry

    Science.gov (United States)

    Busta, Heinz H.

    1981-04-01

    A laser interferometric method was developed to detect end-of-etching of materials such as doped and undoped polysilicon, Si3N4, Si02 and metals used during different stages of IC and thin film device processing. For metal etching, a detector trace of constant magnitude is obtained until the underlying layers are exposed. At this point, a step change in re-flectivity occurs, signaling the end-point. For the other above mentioned films, a sinu-soidal waveform is obtained which changes its frequency once the film of interest is etched and the underlying layers become exposed. The method is applicable to all of the dry etch-ing processes and will be illustrated in some detail for polysilicon and silicon nitride etching applications using a barrel-type plasma reactor.

  14. The application of acoustic emission for detecting incipient cavitation and the best efficiency point of a 60 kW centrifugal pump: case study

    OpenAIRE

    Alfayez, L; Mba, David; Dyson, G.

    2005-01-01

    Pumps play a significant role in industrial plants and need continuous monitoring to minimise loss of production. To date, there is limited published information on the application of acoustic emission (AE) to incipient pump cavitation. This paper presents a case study where AE has been applied for detecting incipient cavitation and determining the best efficiency point (BEP) of a 60 kW centrifugal pump. Results presented are based on net positive suction head (NPSH) and per...

  15. Protein Adsorption and Reorganization on Nanoparticles Probed by the Coffee-Ring Effect: Application to Single Point Mutation Detection.

    Science.gov (United States)

    Devineau, Stéphanie; Anyfantakis, Manos; Marichal, Laurent; Kiger, Laurent; Morel, Mathieu; Rudiuk, Sergii; Baigl, Damien

    2016-09-14

    The coffee-ring effect denotes the accumulation of particles at the edge of an evaporating sessile drop pinned on a substrate. Because it can be detected by simple visual inspection, this ubiquitous phenomenon can be envisioned as a robust and cost-effective diagnostic tool. Toward this direction, here we systematically analyze the deposit morphology of drying drops containing polystyrene particles of different surface properties with various proteins (bovine serum albumin (BSA) and different forms of hemoglobin). We show that deposit patterns reveal information on both the adsorption of proteins onto particles and their reorganization following adsorption. By combining pattern analysis with adsorption isotherm and zeta potential measurements, we show that the suppression of the coffee-ring effect and the formation of a disk-shaped pattern is primarily associated with particle neutralization by protein adsorption. However, our findings also suggest that protein reorganization following adsorption can dramatically invert this tendency. Exposure of hydrophobic (respectively charged) residues can lead to disk (respectively ring) deposit morphologies independently of the global particle charge. Surface tension measurements and microscopic observations of the evaporating drops show that the determinant factor of the deposit morphology is the accumulation of particles at the liquid/gas interface during evaporation. This general behavior opens the possibility to probe protein adsorption and reorganization on particles by the analysis of the deposit patterns, the formation of a disk being the robust signature of particles rendered hydrophobic by protein adsorption. We show that this method is sensitive enough to detect a single point mutation in a protein, as demonstrated here by the distinct patterns formed by human native hemoglobin h-HbA and its mutant form h-HbS, which is responsible for sickle cell anemia. PMID:27562632

  16. Application of flat panel OLED display technology for the point-of-care detection of circulating cancer biomarkers

    OpenAIRE

    Katchman, Benjamin A; Smith, Joseph T.; Uwadiae Obahiagbon; Sailaja Kesiraju; Yong-Kyun Lee; Barry O’Brien; Korhan Kaftanoglu; Jennifer Blain Christen; Anderson, Karen S.

    2016-01-01

    Point-of-care molecular diagnostics can provide efficient and cost-effective medical care, and they have the potential to fundamentally change our approach to global health. However, most existing approaches are not scalable to include multiple biomarkers. As a solution, we have combined commercial flat panel OLED display technology with protein microarray technology to enable high-density fluorescent, programmable, multiplexed biorecognition in a compact and disposable configuration with cli...

  17. Infrared point sensors for homeland defense applications

    Science.gov (United States)

    Thomas, Ross C.; Carter, Michael T.; Homrighausen, Craig L.

    2004-03-01

    We report recent progress toward the development of infrared point sensors for the detection of chemical warfare agents and explosive related chemicals, which pose a significant threat to both health and environment. Technical objectives have focused on the development of polymer sorbents to enhance the infrared response of these hazardous organic compounds. For example, infrared point sensors which part-per-billion detection limits have been developed that rapidlypartition chemical warfare agents and explosive related chemicals into polymer thin films with desirable chemical and physical properties. These chemical sensors demonstrate novel routes to reversible sensing of hazardous organic compounds. The development of small, low-power, sensitive, and selective instruments employing these chemical sensors would enhance the capabilities of federal, state, and local emergency response to incidents involving chemical terrorism. Specific applications include chemical defense systems for military personnel and homeland defense, environmental monitors for remediation and demilitarization, and point source detectors for emergency and maintenance response teams.

  18. Detecting change-points in extremes

    KAUST Repository

    Dupuis, D. J.

    2015-01-01

    Even though most work on change-point estimation focuses on changes in the mean, changes in the variance or in the tail distribution can lead to more extreme events. In this paper, we develop a new method of detecting and estimating the change-points in the tail of multiple time series data. In addition, we adapt existing tail change-point detection methods to our specific problem and conduct a thorough comparison of different methods in terms of performance on the estimation of change-points and computational time. We also examine three locations on the U.S. northeast coast and demonstrate that the methods are useful for identifying changes in seasonally extreme warm temperatures.

  19. SINGULAR POINT DETECTION FOR EFFICIENT FINGERPRINT CLASSIFICATION

    OpenAIRE

    Ali Ismail Awad; Kensuke Baba

    2012-01-01

    A singular point or singularity on fingerprint is considered as a fingerprint landmark due its scale, shift, and rotation immutability. It is used for both fingerprint classification and alignment in automatic fingerprint identification systems. This paper presents a comparative study between two singular point detection methods available in the literature. The comparative study has been conducted on the Poincaré index and the complex filter methods, and it aims to catch the optimum singular...

  20. Detection of point landmarks in multidimensional tensor data☆

    OpenAIRE

    Ruiz-Alzola, J.; Kikinis, R.; Westin, C.-F.

    2001-01-01

    This paper describes a unified approach to the detection of point landmarks—whose neighborhoods convey discriminant information—including multidimensional scalar, vector, and higher-order tensor data. The method is based on the interpretation of generalized correlation matrices derived from the gradient of tensor functions, a probabilistic interpretation of point landmarks, and the application of tensor algebra. Results on both synthetic and real tensor data are presented.

  1. Clinical Application of Point Diji

    Institute of Scientific and Technical Information of China (English)

    栾继萍

    2004-01-01

    @@ Diji (SP 8) is a cleft point of the Spleen Channel of Foot-Taiyang. Its indications include abdominal pain, diarrhea, edema, dysmenorrhea and certain other symptoms caused by incoordination between the liver and the spleen. Either taking the point alone or together with some other adjunct points in clinical practice, the author has obtained satisfactory curative effects.

  2. Identifying image forgeries using change points detection

    Czech Academy of Sciences Publication Activity Database

    Mahdian, Babak; Saic, Stanislav

    Washington: SPIE, 2011, 788008-1-780808-2. ISBN 978-0-8194-8417-8. ISSN 0277-786X. [SPIE Electronic Imaging, Media Watermarking, Security, and Forensics III. San Francisco (US), 22.01.2011-23.01.2011] R&D Projects: GA ČR GA102/08/0470; GA MV VG20102013064 Institutional research plan: CEZ:AV0Z10750506 Keywords : image forgery Subject RIV: JC - Computer Hardware ; Software http://library.utia.cas.cz/separaty/2012/ZOI/mahdian-identifying image forgeries using change points detection.pdf

  3. Optimization of measurement points for damage detection

    OpenAIRE

    Cremona, Christian; ADELAIDE, Lucas

    2009-01-01

    Dynamical assessment is often employed to evaluate structures in civil engineering. This non-destructive surveillance technique became an attractive approach in order to show the existence of damages and to predict its location. The modal parameters of the structure are determined by modal identification methods without any prior knowledge of the nature of the excitation. The application of damage detection and localization techniques is performed by comparing the variation of the modal param...

  4. Dark Matter Detection in Focus Point Supersymmetry

    CERN Document Server

    Draper, Patrick; Kant, Philipp; Profumo, Stefano; Sanford, David

    2013-01-01

    We determine the prospects for direct and indirect detection of thermal relic neutralinos in supersymmetric theories with multi-TeV squarks and sleptons. We consider the concrete example of the focus point region of minimal supergravity, but our results are generically valid for all models with decoupled scalars and mixed Bino-Higgsino or Higgsino-like dark matter. We determine the parameter space consistent with a 125 GeV Higgs boson including 3-loop corrections in the calculation of the Higgs mass. These corrections increase $m_h$ by 1--3 GeV, lowering the preferred scalar mass scale and decreasing the fine-tuning measure in these scenarios. We then systematically examine prospects for dark matter direct and indirect detection. Direct detection constraints do not exclude these models, especially for $\\mu < 0$. At the same time, the scenario generically predicts spin-independent signals just beyond current bounds. We also consider indirect detection with neutrinos, gamma rays, anti-protons, and anti-deute...

  5. Developing SharePoint applications

    OpenAIRE

    Rupnik, Gašper

    2011-01-01

    The thesis includes a research on SharePoint 2010 programming capabilities and a display of products created by this knowledge. The introduction part includes background information on how the topic was chosen and how the thesis was developed. The second chapter presents the SharePoint platform, which includes a description of its structure, function and usability. The third chapter focuses solely on the programming of the platform. First, some of the most useful software tools for i...

  6. Gaussian processes for state space models and change point detection

    OpenAIRE

    Turner, Ryan Darby

    2012-01-01

    This thesis details several applications of Gaussian processes (GPs) for enhanced time series modeling. We first cover different approaches for using Gaussian processes in time series problems. These are extended to the state space approach to time series in two different problems. We also combine Gaussian processes and Bayesian online change point detection (BOCPD) to increase the generality of the Gaussian process time series methods. These methodologies are evaluated on predict...

  7. Clinical Application of the Point Yongquan

    Institute of Scientific and Technical Information of China (English)

    刘赞超; 刘宏; 张浩; 孙申田

    2002-01-01

    @@ Yongquan (KI 1) is a jing (well) point of the Kidney Meridian of Foot-Shaoyin. As this point is widely used for treatment of acute or chronic diseases, it has drawn attentions from physicians both in the ancient and in the present times. If this point is taken accurately and the differentiation of disease is made properly, both the needling and the external drug application can achieve satisfactory therapeutic results.

  8. Nearest Neighbour Corner Points Matching Detection Algorithm

    OpenAIRE

    Zhang Changlong; Wang Miaomiao; Li Yong; Yang Xuesong

    2015-01-01

    Accurate detection towards the corners plays an important part in camera calibration. To deal with the instability and inaccuracies of present corner detection algorithm, the nearest neighbour corners match-ing detection algorithms was brought forward. First, it dilates the binary image of the photographed pictures, searches and reserves quadrilateral outline of the image. Second, the blocks which accord with chess-board-corners are classified into a class. If too many blocks in class, it wil...

  9. DETECTION OF ROAD CURB FROM MOBILE TERRESTRIAL LASER SCANNER POINT CLOUD

    OpenAIRE

    El-Halawany, S.; Moussa, A.; D. D. Lichti; N. El-Sheimy

    2012-01-01

    The detection of different road furniture such as curb, street floor and sidewalk from point clouds is important in many applications such as road maintenance and city planning. In this paper a pipeline for point cloud processing to detect the road curb from unorganized point clouds captured from a mobile terrestrial laser scanner is proposed. The proposed pipeline utilizes a covariance- based procedure to perform a 3D segmentation of point clouds. Features such as the road curb can be extrac...

  10. Nearest Neighbour Corner Points Matching Detection Algorithm

    Directory of Open Access Journals (Sweden)

    Zhang Changlong

    2015-01-01

    Full Text Available Accurate detection towards the corners plays an important part in camera calibration. To deal with the instability and inaccuracies of present corner detection algorithm, the nearest neighbour corners match-ing detection algorithms was brought forward. First, it dilates the binary image of the photographed pictures, searches and reserves quadrilateral outline of the image. Second, the blocks which accord with chess-board-corners are classified into a class. If too many blocks in class, it will be deleted; if not, it will be added, and then let the midpoint of the two vertex coordinates be the rough position of corner. At last, it precisely locates the position of the corners. The Experimental results have shown that the algorithm has obvious advantages on accuracy and validity in corner detection, and it can give security for camera calibration in traffic accident measurement.

  11. Bisous model-Detecting filamentary patterns in point processes

    Science.gov (United States)

    Tempel, E.; Stoica, R. S.; Kipper, R.; Saar, E.

    2016-07-01

    The cosmic web is a highly complex geometrical pattern, with galaxy clusters at the intersection of filaments and filaments at the intersection of walls. Identifying and describing the filamentary network is not a trivial task due to the overwhelming complexity of the structure, its connectivity and the intrinsic hierarchical nature. To detect and quantify galactic filaments we use the Bisous model, which is a marked point process built to model multi-dimensional patterns. The Bisous filament finder works directly with the galaxy distribution data and the model intrinsically takes into account the connectivity of the filamentary network. The Bisous model generates the visit map (the probability to find a filament at a given point) together with the filament orientation field. Using these two fields, we can extract filament spines from the data. Together with this paper we publish the computer code for the Bisous model that is made available in GitHub. The Bisous filament finder has been successfully used in several cosmological applications and further development of the model will allow to detect the filamentary network also in photometric redshift surveys, using the full redshift posterior. We also want to encourage the astro-statistical community to use the model and to connect it with all other existing methods for filamentary pattern detection and characterisation.

  12. The computation of fixed points and applications

    CERN Document Server

    Todd, Michael J

    1976-01-01

    Fixed-point algorithms have diverse applications in economics, optimization, game theory and the numerical solution of boundary-value problems. Since Scarf's pioneering work [56,57] on obtaining approximate fixed points of continuous mappings, a great deal of research has been done in extending the applicability and improving the efficiency of fixed-point methods. Much of this work is available only in research papers, although Scarf's book [58] gives a remarkably clear exposition of the power of fixed-point methods. However, the algorithms described by Scarf have been super~eded by the more sophisticated restart and homotopy techniques of Merrill [~8,~9] and Eaves and Saigal [1~,16]. To understand the more efficient algorithms one must become familiar with the notions of triangulation and simplicial approxi- tion, whereas Scarf stresses the concept of primitive set. These notes are intended to introduce to a wider audience the most recent fixed-point methods and their applications. Our approach is therefore ...

  13. A New Fixed Point Theorem and Applications

    Directory of Open Access Journals (Sweden)

    Min Fang

    2013-01-01

    Full Text Available A new fixed point theorem is established under the setting of a generalized finitely continuous topological space (GFC-space without the convexity structure. As applications, a weak KKM theorem and a minimax inequalities of Ky Fan type are also obtained under suitable conditions. Our results are different from known results in the literature.

  14. Four-Point Wavelets and Their Applications

    Institute of Scientific and Technical Information of China (English)

    魏国富; 陈发来

    2002-01-01

    Multiresolution analysis (MRA) and wavelets provide useful and efficient tools for representing functions at multiple levels of details. Wavelet representations have been used in a broad range of applications, including image compression, physical simulation and numerical analysis. In this paper, the authors construct a new class of wavelets, called four-point wavelets,based on an interpolatory four-point subdivision scheme. They are of local support, symmetric and stable. The analysis and synthesis algorithms have linear time complexity. Depending on different weight parameters w, the scaling functions and wavelets generated by the four-point subdivision scheme are of different degrees of smoothness. Therefore the user can select better wavelets relevant to the practice among the classes of wavelets. The authors apply the fourpoint wavelets in signal compression. The results show that the four-point wavelets behave much better than B-spline wavelets in many situations.

  15. Research Update: Point defects in CdTexSe1−x crystals grown from a Te-rich solution for applications in detecting radiation

    Directory of Open Access Journals (Sweden)

    R. Gul

    2015-04-01

    Full Text Available We investigated cadmium telluride selenide (CdTeSe crystals, newly grown by the Traveling Heater Method (THM, for the presence and abundance of point defects. Current Deep Level Transient spectroscopy (I-DLTS was used to determine the energies of the traps, their capture cross sections, and densities. The bias across the detectors was varied from 1 to 30 V. Four types of point defects were identified, ranging from 10 meV to 0.35 eV. Two dominant traps at energies of 0.18 eV and 0.14 eV were studied in depth. Cd vacancies are found at lower concentrations than other point defects present in the material.

  16. Implementation of two high through-put techniques in a novel application: detecting point mutations in large EMS mutated plant populations

    Directory of Open Access Journals (Sweden)

    van Loo Eibertus N

    2009-10-01

    Full Text Available Abstract Background The establishment of mutant populations together with the strategies for targeted mutation detection has been applied successfully to a large number of organisms including many species in the plant kingdom. Considerable efforts have been invested into research on tomato as a model for berry-fruit plants. With the progress of the tomato sequencing project, reverse genetics becomes an obvious and achievable goal. Results Here we describe the treatment of Solanum lycopersicum seeds with 1% EMS and the development of a new mutated tomato population. To increase targeted mutant detection throughput an automated seed DNA extraction has been combined with novel mutation detection platforms for TILLING in plants. We have adapted two techniques used in human genetic diagnostics: Conformation Sensitive Capillary Electrophoresis (CSCE and High Resolution DNA Melting Analysis (HRM to mutation screening in DNA pools. Classical TILLING involves critical and time consuming steps such as endonuclease digestion reactions and gel electrophoresis runs. Using CSCE or HRM, the only step required is a simple PCR before either capillary electrophoresis or DNA melting curve analysis. Here we describe the development of a mutant tomato population, the setting up of two polymorphism detection platforms for plants and the results of the first screens as mutation density in the populations and estimation of the false-positives rate when using HRM to screen DNA pools. Conclusion These results demonstrate that CSCE and HRM are fast, affordable and sensitive techniques for mutation detection in DNA pools and therefore allow the rapid identification of new allelic variants in a mutant population. Results from the first screens indicate that the mutagen treatment has been effective with an average mutation detection rate per diploid genome of 1.36 mutation/kb/1000 lines.

  17. Fixed point theorems and their applications

    CERN Document Server

    Farmakis, Ioannis

    2013-01-01

    This is the only book that deals comprehensively with fixed point theorems overall of mathematics. Their importance is due, as the book demonstrates, to their wide applicability. Beyond the first chapter, each of the other seven can be read independently of the others so the reader has much flexibility to follow his/her own interests. The book is written for graduate students and professional mathematicians and could be of interest to physicists, economists and engineers.

  18. Implementation of two high through-put techniques in a novel application: detecting point mutations in large EMS mutated plant populations

    NARCIS (Netherlands)

    Gady, A.L.F.; Hermans, F.W.K.; Wal, van de M.H.B.J.; Loo, van E.N.; Visser, R.G.F.; Bachem, C.W.B.

    2009-01-01

    Background - The establishment of mutant populations together with the strategies for targeted mutation detection has been applied successfully to a large number of organisms including many species in the plant kingdom. Considerable efforts have been invested into research on tomato as a model for b

  19. Fast Change Point Detection for Electricity Market Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Berkeley, UC; Gu, William; Choi, Jaesik; Gu, Ming; Simon, Horst; Wu, Kesheng

    2013-08-25

    Electricity is a vital part of our daily life; therefore it is important to avoid irregularities such as the California Electricity Crisis of 2000 and 2001. In this work, we seek to predict anomalies using advanced machine learning algorithms. These algorithms are effective, but computationally expensive, especially if we plan to apply them on hourly electricity market data covering a number of years. To address this challenge, we significantly accelerate the computation of the Gaussian Process (GP) for time series data. In the context of a Change Point Detection (CPD) algorithm, we reduce its computational complexity from O($n^{5}$) to O($n^{2}$). Our efficient algorithm makes it possible to compute the Change Points using the hourly price data from the California Electricity Crisis. By comparing the detected Change Points with known events, we show that the Change Point Detection algorithm is indeed effective in detecting signals preceding major events.

  20. Change detection in polarimetric SAR data over several time points

    DEFF Research Database (Denmark)

    Conradsen, Knut; Nielsen, Allan Aasbjerg; Skriver, Henning

    2014-01-01

    A test statistic for the equality of several variance-covariance matrices following the complex Wishart distribution is introduced. The test statistic is applied successfully to detect change in C-band EMISAR polarimetric SAR data over four time points....

  1. Light Detection and Ranging Point Cloud Data: 2000 - Present

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — LIDAR (Light Detection and Ranging) discrete-return point cloud data are available in the American Society for Photogrammetry and Remote Sensing (ASPRS) LAS format....

  2. Features Extraction for Object Detection Based on Interest Point

    Directory of Open Access Journals (Sweden)

    Amin Mohamed Ahsan

    2013-05-01

    Full Text Available In computer vision, object detection is an essential process for further processes such as object tracking, analyzing and so on. In the same context, extraction features play important role to detect the object correctly. In this paper we present a method to extract local features based on interest point which is used to detect key-points within an image, then, compute histogram of gradient (HOG for the region surround that point. Proposed method used speed-up robust feature (SURF method as interest point detector and exclude the descriptor. The new descriptor is computed by using HOG method. The proposed method got advantages of both mentioned methods. To evaluate the proposed method, we used well-known dataset which is Caltech101. The initial result is encouraging in spite of using a small data for training.

  3. Feature Point Detection Utilizing the Empirical Mode Decomposition

    Directory of Open Access Journals (Sweden)

    Jesmin Farzana Khan

    2008-08-01

    Full Text Available This paper introduces a novel contour-based method for detecting largely affine invariant interest or feature points. In the first step, image edges are detected by morphological operators, followed by edge thinning. In the second step, corner or feature points are identified based on the local curvature of the edges. The main contribution of this work is the selection of good discriminative feature points from the thinned edges based on the 1D empirical mode decomposition (EMD. Simulation results compare the proposed method with five existing approaches that yield good results. The suggested contour-based technique detects almost all the true feature points of an image. Repeatability rate, which evaluates the geometric stability under different transformations, is employed as the performance evaluation criterion. The results show that the performance of the proposed method compares favorably against the existing well-known methods.

  4. Street environment change detection from mobile laser scanning point clouds

    Science.gov (United States)

    Xiao, Wen; Vallet, Bruno; Brédif, Mathieu; Paparoditis, Nicolas

    2015-09-01

    Mobile laser scanning (MLS) has become a popular technique for road inventory, building modelling, infrastructure management, mobility assessment, etc. Meanwhile, due to the high mobility of MLS systems, it is easy to revisit interested areas. However, change detection using MLS data of street environment has seldom been studied. In this paper, an approach that combines occupancy grids and a distance-based method for change detection from MLS point clouds is proposed. Unlike conventional occupancy grids, our occupancy-based method models space based on scanning rays and local point distributions in 3D without voxelization. A local cylindrical reference frame is presented for the interpolation of occupancy between rays according to the scanning geometry. The Dempster-Shafer theory (DST) is utilized for both intra-data evidence fusion and inter-data consistency assessment. Occupancy of reference point cloud is fused at the location of target points and then the consistency is evaluated directly on the points. A point-to-triangle (PTT) distance-based method is combined to improve the occupancy-based method. Because it is robust to penetrable objects, e.g. vegetation, which cause self-conflicts when modelling occupancy. The combined method tackles irregular point density and occlusion problems, also eliminates false detections on penetrable objects.

  5. Automatic Detection of Building Points from LIDAR and Dense Image Matching Point Clouds

    Science.gov (United States)

    Maltezos, E.; Ioannidis, C.

    2015-08-01

    This study aims to detect automatically building points: (a) from LIDAR point cloud using simple techniques of filtering that enhance the geometric properties of each point, and (b) from a point cloud which is extracted applying dense image matching at high resolution colour-infrared (CIR) digital aerial imagery using the stereo method semi-global matching (SGM). At first step, the removal of the vegetation is carried out. At the LIDAR point cloud, two different methods are implemented and evaluated using initially the normals and the roughness values afterwards: (1) the proposed scan line smooth filtering and a thresholding process, and (2) a bilateral filtering and a thresholding process. For the case of the CIR point cloud, a variation of the normalized differential vegetation index (NDVI) is computed for the same purpose. Afterwards, the bare-earth is extracted using a morphological operator and removed from the rest scene so as to maintain the buildings points. The results of the extracted buildings applying each approach at an urban area in northern Greece are evaluated using an existing orthoimage as reference; also, the results are compared with the corresponding classified buildings extracted from two commercial software. Finally, in order to verify the utility and functionality of the extracted buildings points that achieved the best accuracy, the 3D models in terms of Level of Detail 1 (LoD 1) and a 3D building change detection process are indicatively performed on a sub-region of the overall scene.

  6. Detection of ground water leak points and water sampling technique

    Energy Technology Data Exchange (ETDEWEB)

    Harada, Kazuyuki (Tokyo Gas Co., Ltd., Tokyo, (Japan))

    1989-09-10

    In order to realize effective survey for ground water leak points in city gas pipelines and to reduce the repairing period and its cost, development on the survey method and devices were carried out. Then the process to detect ground water leak points and water sampling technique were developed for mainly easily available device and jig. The object of the process is low pressure main and branch pipelines of 50-300mm in diameter, and the process detect ground water leak points without excavation, finds drainage and water sampling is done. It investigates the range of ground water leak points by gas moisture gaze, and specifies ground water leak points by television camera of fiberscope. Water in the pipeline is absorbed by electric motor driven water vacuum pump, applying the hoses provided with water sensor to detect water leak points. The device to be inserted into in-service pipelines was developed so as to safely and surely insert device into in-service pipeline by way of conventional drilling device and coupler. The effective survey for ground leak water is able to realized which was depended upon sixth sense and experience. 1 ref., 5 figs., 1 tab.

  7. Signal detection using change point analysis in postmarket surveillance†

    OpenAIRE

    Xu, Zhiheng; Kass-Hout, Taha; Anderson-Smits, Colin; Gray, Gerry

    2015-01-01

    Purpose Signal detection methods have been used extensively in postmarket surveillance to identify elevated risks of adverse events associated with medical products (drugs, vaccines, and devices). However, current popular disproportionality methods ignore useful information such as trends when the data are aggregated over time for signal detection. Methods In this paper, we applied change point analysis (CPA) to trend analysis of medical products in a spontaneous adverse event reporting syste...

  8. Point Mutation Identification Using On-Chip Ligase Detection Reaction

    Institute of Scientific and Technical Information of China (English)

    李艳; 曾令文; 程京

    2004-01-01

    An efficient method was developed to detect point mutations using oligonucleotide microarrays and the ligase detection reaction (LDR).Allele-specific LDR primers were immobilized on polylysine-coated glass slides to perform LDR on a chip.The spotting concentration and detection limit were analyzed using a synthesized oligonucleotide as a template.The optimal primer spotting concentration was 20 (mol/L and the lowest detectable template concentration was 0.33 nmol/L.The method was successfully employed to identify malignant mutations of hypertrophic cardiomyopathy.Asymmetric polymerase chain reaction was employed to prepare single stranded DNA as LDR templates from cloned plasmids.The discrimination ratios for AC,TC,GT,TT,GA,and AA mismatches are 32.82,44.24,17.75,18.34,11.66,and 8.91,respectively.This method may allow construction of multiple mutation detection systems.

  9. Comparison of methods for accurate end-point detection of potentiometric titrations

    Science.gov (United States)

    Villela, R. L. A.; Borges, P. P.; Vyskočil, L.

    2015-01-01

    Detection of the end point in potentiometric titrations has wide application on experiments that demand very low measurement uncertainties mainly for certifying reference materials. Simulations of experimental coulometric titration data and consequential error analysis of the end-point values were conducted using a programming code. These simulations revealed that the Levenberg-Marquardt method is in general more accurate than the traditional second derivative technique used currently as end-point detection for potentiometric titrations. Performance of the methods will be compared and presented in this paper.

  10. Vehicle Localization by LIDAR Point Correlation Improved by Change Detection

    Science.gov (United States)

    Schlichting, A.; Brenner, C.

    2016-06-01

    LiDAR sensors are proven sensors for accurate vehicle localization. Instead of detecting and matching features in the LiDAR data, we want to use the entire information provided by the scanners. As dynamic objects, like cars, pedestrians or even construction sites could lead to wrong localization results, we use a change detection algorithm to detect these objects in the reference data. If an object occurs in a certain number of measurements at the same position, we mark it and every containing point as static. In the next step, we merge the data of the single measurement epochs to one reference dataset, whereby we only use static points. Further, we also use a classification algorithm to detect trees. For the online localization of the vehicle, we use simulated data of a vertical aligned automotive LiDAR sensor. As we only want to use static objects in this case as well, we use a random forest classifier to detect dynamic scan points online. Since the automotive data is derived from the LiDAR Mobile Mapping System, we are able to use the labelled objects from the reference data generation step to create the training data and further to detect dynamic objects online. The localization then can be done by a point to image correlation method using only static objects. We achieved a localization standard deviation of about 5 cm (position) and 0.06° (heading), and were able to successfully localize the vehicle in about 93 % of the cases along a trajectory of 13 km in Hannover, Germany.

  11. A micro dew point sensor with a thermal detection principle

    Science.gov (United States)

    Kunze, M.; Merz, J.; Hummel, W.-J.; Glosch, H.; Messner, S.; Zengerle, R.

    2012-01-01

    We present a dew point temperature sensor with the thermal detection of condensed water on a thin membrane, fabricated by silicon micromachining. The membrane (600 × 600 × ~1 µm3) is part of a silicon chip and contains a heating element as well as a thermopile for temperature measurement. By dynamically heating the membrane and simultaneously analyzing the transient increase of its temperature it is detected whether condensed water is on the membrane or not. To cool the membrane down, a peltier cooler is used and electronically controlled in a way that the temperature of the membrane is constantly held at a value where condensation of water begins. This temperature is measured and output as dew point temperature. The sensor system works in a wide range of dew point temperatures between 1 K and down to 44 K below air temperature. In experimental investigations it could be proven that the deviation of the measured dew point temperatures compared to reference values is below ±0.2 K in an air temperature range of 22 to 70 °C. At low dew point temperatures of -20 °C (air temperature = 22 °C) the deviation increases to nearly -1 K.

  12. Fast and robust dominant point detection on digital curves

    OpenAIRE

    Nguyen, Thanh Phuong; Debled-Rennesson, Isabelle

    2009-01-01

    A new and fast method for dominant point detection and polygonal representation of a discrete curve is proposed. Starting from results of discrete geometry, the notion of maximal blurred segment of width v has been proposed, well adapted to possibly noisy and/or not connected curves. For a given width, the dominant points of a curve C are deduced from the sequence of maximal blurred segments of C in O(nlog^2n) time. Comparisons with other methods of the literature prove the efficiency of our ...

  13. MOTION DETECTION USING THE SPACE-TIME INTEREST POINTS

    Directory of Open Access Journals (Sweden)

    Insaf Bellamine

    2014-01-01

    Full Text Available Space-Time Interest Points (STIP are among all the interesting features which can be extracted from videos; they are simple, robust and they allow a good characterization of a set of regions of interest corresponding to moving objects in a three-dimensional observed scene. In this study, we show how the resulting features often reflect interesting events that can be used for a compact representation of video data as well as for tracking. For a good detection of moving objects, we propose to apply the algorithm of the detection of spatiotemporal interest points on both components of the decomposition which is based on a Partial Differential Equation (PDE: A geometric structure component and a texture component. Proposed results are obtained from very different types of videos, namely sport videos and animation movies.

  14. Sharpening of Video Frames for Improvement of Feature Points Detection

    OpenAIRE

    Sergey A. Turko; Ilia V. Safonov

    2016-01-01

    Some visual tracking tasks are unable to operate stable for video with blurred frames because feature points detection is degraded on blur images. In the paper we concentrate on blurriness due to refocusing of camera optical system of mobile devices. Our aim is evaluation of influence of blur and sharpening on Harris corner and FAST keypoints detectors. We propose a quality criterion in order to be able to make numerical assessment of the influence. For enhancement of blurred frames we invest...

  15. Sequential change-point detection based on nearest neighbors

    OpenAIRE

    Chen, Hao

    2016-01-01

    We propose a new framework for the detection of change points in online, sequential data analysis. The approach utilizes nearest neighbor information and can be applied to multivariate or object data sequences. Different stopping rules are explored, and one specific rule is recommended due to its desirable properties. An accurate analytic approximation of the average run length is derived for the recommended rule, making it an easy off-the-shelf approach for real multivariate/object sequentia...

  16. LIDAR, Point Clouds, and their Archaeological Applications

    Energy Technology Data Exchange (ETDEWEB)

    White, Devin A [ORNL

    2013-01-01

    It is common in contemporary archaeological literature, in papers at archaeological conferences, and in grant proposals to see heritage professionals use the term LIDAR to refer to high spatial resolution digital elevation models and the technology used to produce them. The goal of this chapter is to break that association and introduce archaeologists to the world of point clouds, in which LIDAR is only one member of a larger family of techniques to obtain, visualize, and analyze three-dimensional measurements of archaeological features. After describing how point clouds are constructed, there is a brief discussion on the currently available software and analytical techniques designed to make sense of them.

  17. Knowledge-Based Object Detection in Laser Scanning Point Clouds

    Science.gov (United States)

    Boochs, F.; Karmacharya, A.; Marbs, A.

    2012-07-01

    Object identification and object processing in 3D point clouds have always posed challenges in terms of effectiveness and efficiency. In practice, this process is highly dependent on human interpretation of the scene represented by the point cloud data, as well as the set of modeling tools available for use. Such modeling algorithms are data-driven and concentrate on specific features of the objects, being accessible to numerical models. We present an approach that brings the human expert knowledge about the scene, the objects inside, and their representation by the data and the behavior of algorithms to the machine. This "understanding" enables the machine to assist human interpretation of the scene inside the point cloud. Furthermore, it allows the machine to understand possibilities and limitations of algorithms and to take this into account within the processing chain. This not only assists the researchers in defining optimal processing steps, but also provides suggestions when certain changes or new details emerge from the point cloud. Our approach benefits from the advancement in knowledge technologies within the Semantic Web framework. This advancement has provided a strong base for applications based on knowledge management. In the article we will present and describe the knowledge technologies used for our approach such as Web Ontology Language (OWL), used for formulating the knowledge base and the Semantic Web Rule Language (SWRL) with 3D processing and topologic built-ins, aiming to combine geometrical analysis of 3D point clouds, and specialists' knowledge of the scene and algorithmic processing.

  18. Growth Curve Analysis and Change-Points Detection in Extremes

    KAUST Repository

    Meng, Rui

    2016-05-15

    The thesis consists of two coherent projects. The first project presents the results of evaluating salinity tolerance in barley using growth curve analysis where different growth trajectories are observed within barley families. The study of salinity tolerance in plants is crucial to understanding plant growth and productivity. Because fully-automated smarthouses with conveyor systems allow non-destructive and high-throughput phenotyping of large number of plants, it is now possible to apply advanced statistical tools to analyze daily measurements and to study salinity tolerance. To compare different growth patterns of barley variates, we use functional data analysis techniques to analyze the daily projected shoot areas. In particular, we apply the curve registration method to align all the curves from the same barley family in order to summarize the family-wise features. We also illustrate how to use statistical modeling to account for spatial variation in microclimate in smarthouses and for temporal variation across runs, which is crucial for identifying traits of the barley variates. In our analysis, we show that the concentrations of sodium and potassium in leaves are negatively correlated, and their interactions are associated with the degree of salinity tolerance. The second project studies change-points detection methods in extremes when multiple time series data are available. Motived by the scientific question of whether the chances to experience extreme weather are different in different seasons of a year, we develop a change-points detection model to study changes in extremes or in the tail of a distribution. Most of existing models identify seasons from multiple yearly time series assuming a season or a change-point location remains exactly the same across years. In this work, we propose a random effect model that allows the change-point to vary from year to year, following a given distribution. Both parametric and nonparametric methods are developed

  19. Studies for detection of weak points in the Brennelementwerk Hanau

    International Nuclear Information System (INIS)

    Within the framework of summary proceedings the Hessian Higher Administrative Court had to decide whether the Hessian Nuclear Supervisory Authority has the Competence to issue an order to Siemens AG - for immediate enforcement -, to allow two employees of the Oeko-Institut free access to the Siemens MOX fuel fabrication plant in order to perform studies for detection of weak points of the processing system, and to give them the necessary assistance for achievement of this task. The Siemens AG sought indicial remedy against this order in an action brought before the Higher Administrative Court, and the Court disallowed the claim in its decision of September 10, 1991. (orig.)

  20. Constructing an optimal decision tree for FAST corner point detection

    KAUST Repository

    Alkhalid, Abdulaziz

    2011-01-01

    In this paper, we consider a problem that is originated in computer vision: determining an optimal testing strategy for the corner point detection problem that is a part of FAST algorithm [11,12]. The problem can be formulated as building a decision tree with the minimum average depth for a decision table with all discrete attributes. We experimentally compare performance of an exact algorithm based on dynamic programming and several greedy algorithms that differ in the attribute selection criterion. © 2011 Springer-Verlag.

  1. Fast, sensitive point of care electrochemical molecular system for point mutation and select agent detection.

    Science.gov (United States)

    MacLeod, J A; Nemeth, A C; Dicke, W C; Wang, D; Manalili Wheeler, S; Hannis, J C; Collier, G B; Drader, J J

    2016-07-01

    Point of care molecular diagnostics benefits from a portable battery-operated device capable of performing a fast turnaround using reliable inexpensive cartridges. We describe a prototype device for performing a molecular diagnostics test for clinical and biodefense samples in 16 minutes using a prototype capable of an 8 minute PCR reaction, followed by hybridization and detection on an electrochemical microarray based on the i-STAT® system. We used human buccal swabs for hemochromatosis testing including in-device DNA extraction. Additional clinical and biodefense samples included influenza A and bacterial select agents Bacillus anthracis, Yersinia pestis and Francisella tularensis. PMID:27280174

  2. Regulatory point of view of SAT application

    International Nuclear Information System (INIS)

    I present the regulatory system for monitoring operator training and check competency of operator personnel in Hungary and the effects of SAT to the regulatory framework/practice related to recruitment, training and authorisation of operating personnel. Also I introduce an application to manage the initial and refreshing training to regulatory bodies. (author)

  3. Outlier Detection: Applications And Techniques

    Directory of Open Access Journals (Sweden)

    Karanjit Singh

    2012-01-01

    Full Text Available Outliers once upon a time regarded as noisy data in statistics, has turned out to be an important problem which is being researched in diverse fields of research and application domains. Many outlier detection techniques have been developed specific to certain application domains, while some techniques are more generic. Some application domains are being researched in strict confidentiality such as research on crime and terrorist activities. The techniques and results of such techniques are not readily forthcoming. A number of surveys, research and review articles and books cover outlier detection techniques in machine learning and statistical domains individually in great details. In this paper we make an attempt to bring together various outlier detection techniques, in a structured and generic description. With this exercise, we hope to attain a better understanding of the different directions of research on outlier analysis for ourselves as well as for beginners in this research field who could then pick up the links to different areas of applications in details.

  4. Fixed Point Theory in -Complete Metric Spaces with Applications

    OpenAIRE

    Hussain, N.; Kutbi, M. A.; P. Salimi

    2014-01-01

    The aim of this paper is to introduce new concepts of $\\alpha $ - $\\eta $ -complete metric space and $\\alpha $ - $\\eta $ -continuous function and establish fixed point results for modified $\\alpha $ - $\\eta $ - $\\psi $ -rational contraction mappings in $\\alpha $ - $\\eta $ -complete metric spaces. As an application, we derive some Suzuki type fixed point theorems and new fixed point theorems for $\\psi $ -graphic-rational contractions. Moreover, some examples and an application to integra...

  5. Point-point and point-line moving-window correlation spectroscopy and its applications

    Science.gov (United States)

    Zhou, Qun; Sun, Suqin; Zhan, Daqi; Yu, Zhiwu

    2008-07-01

    In this paper, we present a new extension of generalized two-dimensional (2D) correlation spectroscopy. Two new algorithms, namely point-point (P-P) correlation and point-line (P-L) correlation, have been introduced to do the moving-window 2D correlation (MW2D) analysis. The new method has been applied to a spectral model consisting of two different processes. The results indicate that P-P correlation spectroscopy can unveil the details and re-constitute the entire process, whilst the P-L can provide general feature of the concerned processes. Phase transition behavior of dimyristoylphosphotidylethanolamine (DMPE) has been studied using MW2D correlation spectroscopy. The newly proposed method verifies that the phase transition temperature is 56 °C, same as the result got from a differential scanning calorimeter. To illustrate the new method further, a lysine and lactose mixture has been studied under thermo perturbation. Using the P-P MW2D, the Maillard reaction of the mixture was clearly monitored, which has been very difficult using conventional display of FTIR spectra.

  6. Autonomous Onboard Point Source Detection by Small Exploration Spacecraft

    Science.gov (United States)

    Huffman, W.; Thompson, D. R.; Bue, B.; Castillo-Rogez, J.; Boland, J.

    2015-12-01

    Small spacecraft platforms are a promising low-cost approach to accelerate exploration of small bodies, addressing the space community's interest in origin science, planetary resources, and planetary defense. However, they can be challenging platforms for detecting and imaging low brightness targets. Difficulties include constrained bandwidth, which limits the volume of data that can be downlinked; attitude instability, which limits exposure time; small instrument apertures, which reduce sensitivity; and cosmic ray contamination, which creates illusory sources. Mission designers can address all these problems simultaneously by shifting image analysis across the communications gap. Spacecraft can use onboard data analysis to detect sources directly, or downlink parsimonious summary products for detection on the ground. One promising approach is to acquire stacks of short consecutive exposures, and then coregister and coadd them onboard. This work analyzes a coaddition algorithm that is designed to be robust against small spacecraft challenges. We evaluate factors affecting performance, such as attitude control and camera noise systematics, in regimes typical of small spacecraft missions. We motivate the algorithm design by considering its application to NEAScout, a mission representing a new generation of small (sub-50 kg) exploration spacecraft having very small instrument apertures and data rates below 1 kbyte s-1. Here, onboard analysis allows detection and rendezvous with far smaller and fainter objects, dramatically reducing the cost and complexity of primitive bodies exploration.

  7. Bisous model - detecting filamentary patterns in point processes

    CERN Document Server

    Tempel, E; Kipper, R; Saar, E

    2016-01-01

    The cosmic web is a highly complex geometrical pattern, with galaxy clusters at the intersection of filaments and filaments at the intersection of walls. Identifying and describing the filamentary network is not a trivial task due to the overwhelming complexity of the structure, its connectivity and the intrinsic hierarchical nature. To detect and quantify galactic filaments we use the Bisous model, which is a marked point process built to model multi-dimensional patterns. The Bisous filament finder works directly with the galaxy distribution data and the model intrinsically takes into account the connectivity of the filamentary network. The Bisous model generates the visit map (the probability to find a filament at a given point) together with the filament orientation field. Using these two fields, we can extract filament spines from the data. Together with this paper we publish the computer code for the Bisous model that is made available in GitHub. The Bisous filament finder has been successfully used in s...

  8. DETECTION OF ROAD CURB FROM MOBILE TERRESTRIAL LASER SCANNER POINT CLOUD

    Directory of Open Access Journals (Sweden)

    S. El-Halawany

    2012-09-01

    Full Text Available The detection of different road furniture such as curb, street floor and sidewalk from point clouds is important in many applications such as road maintenance and city planning. In this paper a pipeline for point cloud processing to detect the road curb from unorganized point clouds captured from a mobile terrestrial laser scanner is proposed. The proposed pipeline utilizes a covariance- based procedure to perform a 3D segmentation of point clouds. Features such as the road curb can be extracted by analyzing the local neighborhood of every point. This is done by computing the surface normal direction and the normalized eigenvalues. These parameters can be used to extract the ground objects, such as curb, street floor and sidewalk. The curb can be isolated from the rest of the ground objects based on the previous parameters in addition to elevation gradient within the local neighborhood. A 2D image processing scheme is also presented to find the curbs as edges in a generated 2D height image. The results show successful detection rates of 78% and 94% using 3D and 2D approaches respectively.

  9. History and Point in Time in Enterprise Applications

    Directory of Open Access Journals (Sweden)

    Constantin Gelu APOSTOL

    2006-01-01

    Full Text Available First part points out the main differences between temporal and non-temporal databases. In the second part, based on identification of the three main categories of time involved in database applications: user-defined time, valid time and transaction time, some relevant solutions for their implementation are discussed, mainly from the point of view of database organization and data access level of enterprise applications. The final part is dedicated to the influences of historical data in the business logic and presentation levels of enterprise applications and in application services, as security, workflow, reporting.

  10. Empirical Spectral Processes and Their Applications to Stationary Point Processes

    OpenAIRE

    Eichler, Michael

    1995-01-01

    We consider empirical spectral processes indexed by classes of functions for the case of stationary point processes. Conditions for the measurability and equicontinuity of these processes and a weak convergence result are established. The results can be applied to the spectral analysis of point processes. In particular, we discuss the application to parametric and nonparametric spectral density estimation.

  11. Multi-point cooperative communication systems theory and applications

    CERN Document Server

    Ding, Ming

    2013-01-01

    Multi-point Cooperative Communication Systems: Theory and Applications mainly discusses multi-point cooperative communication technologies which are used to overcome the long-standing problem of limited transmission rate caused by the inter-point interference. Instead of combating the interference, recent progress in both academia and industrial standardizations has evolved to adopt the philosophy of “exploiting” the interference to improve the transmission rate by cooperating among multiple points. This book addresses the multi-point cooperative communication system systematically giving  the readers a clear picture of the technology map and where the discussed schemes may fit. This book includes not only the theories of the paradigm-shifting multi-point cooperative communication, but also the designs of sub-optimal cooperative communication schemes for practical systems. Ming Ding is a senior researcher at Sharp Laboratories of China; Hanwen Luo is a professor at Shanghai Jiao Tong University.

  12. Nanoparticle Detection of Urinary Markers for Point-of-Care Diagnosis of Kidney Injury.

    Directory of Open Access Journals (Sweden)

    Hyun Jung Chung

    Full Text Available The high incidence of acute and chronic kidney injury due to various environmental factors such as heavy metals or chemicals has been a major problem in developing countries. However, the diagnosis of kidney injury in these areas can be more challenging due to the lack of highly sensitive and specific techniques that can be applied in point-of-care settings. To address this, we have developed a technique called 'micro-urine nanoparticle detection (μUNPD', that allows the detection of trace amounts of molecular markers in urine. Specifically, this technique utilizes an automated on-chip assay followed by detection with a hand-held device for the read-out. Using the μUNPD technology, the kidney injury markers KIM-1 and Cystatin C were detected down to concentrations of 0.1 ng/ml and 20 ng/ml respectively, which meets the cut-off range required to identify patients with acute or chronic kidney injury. Thus, we show that the μUNPD technology enables point of care and non-invasive detection of kidney injury, and has potential for applications in diagnosing kidney injury with high sensitivity in resource-limited settings.

  13. Implementation of the 7-point checklist for melanoma detection on smart handheld devices.

    Science.gov (United States)

    Wadhawan, Tarun; Situ, Ning; Rui, Hu; Lancaster, Keith; Yuan, Xiaojing; Zouridakis, George

    2011-01-01

    In this paper we implement the 7-point checklist, a set of dermoscopic criteria widely used by clinicians for melanoma detection, on smart handheld devices, such as the Apple iPhone and iPad. The application developed is using sophisticated image processing and pattern recognition algorithms, yet it is light enough to run on a handheld device with limited memory and computational speed. When combined with a commercially available handheld dermoscope that provides proper lesion illumination, this application provides a truly self-contained handheld system for melanoma detection. Such a device can be used in a clinical setting for routine skin screening, or as an assistive diagnostic device in underserved areas and in developing countries with limited healthcare infrastructure. PMID:22255015

  14. Nonparametric decomposition of quasi-periodic time series for change-point detection

    Science.gov (United States)

    Artemov, Alexey; Burnaev, Evgeny; Lokot, Andrey

    2015-12-01

    The paper is concerned with the sequential online change-point detection problem for a dynamical system driven by a quasiperiodic stochastic process. We propose a multicomponent time series model and an effective online decomposition algorithm to approximate the components of the models. Assuming the stationarity of the obtained components, we approach the change-point detection problem on a per-component basis and propose two online change-point detection schemes corresponding to two real-world scenarios. Experimental results for decomposition and detection algorithms for synthesized and real-world datasets are provided to demonstrate the efficiency of our change-point detection framework.

  15. Pedestrian detection for real-life applications

    OpenAIRE

    De Smedt, Floris

    2015-01-01

    The presence of cameras in our surroundings grows every day, allowing object detection, and more specifically pedestrian detection, to be used in a broad amount of applications. Possible applications include surveillance applications, traffic safety, blurring pedestrians for privacy issues and human-robot interaction. In the last decade, pedestrian detection received a lot of attention as a research topic, which resulted in a broad amount of available techniques. In this dissertation, we focu...

  16. KNOWLEDGE-BASED OBJECT DETECTION IN LASER SCANNING POINT CLOUDS

    OpenAIRE

    F. Boochs; Karmacharya, A.; Marbs, A.

    2012-01-01

    Object identification and object processing in 3D point clouds have always posed challenges in terms of effectiveness and efficiency. In practice, this process is highly dependent on human interpretation of the scene represented by the point cloud data, as well as the set of modeling tools available for use. Such modeling algorithms are data-driven and concentrate on specific features of the objects, being accessible to numerical models. We present an approach that brings the human e...

  17. Detection of point mutations by non-isotopic single strand conformation polymorphism

    Directory of Open Access Journals (Sweden)

    N.A. Pinheiro

    1999-01-01

    Full Text Available We have developed a procedure for nonradioactive single strand conformation polymorphism analysis and applied it to the detection of point mutations in the human tumor suppressor gene p53. The protocol does not require any particular facilities or equipment, such as radioactive handling, large gel units for sequencing, or a semiautomated electrophoresis system. This technique consists of amplification of DNA fragments by PCR with specific oligonucleotide primers, denaturation, and electrophoresis on small neutral polyacrylamide gels, followed by silver staining. The sensitivity of this procedure is comparable to other described techniques and the method is easy to perform and applicable to a variety of tissue specimens.

  18. TREES DETECTION FROM LASER POINT CLOUDS ACQUIRED IN DENSE URBAN AREAS BY A MOBILE MAPPING SYSTEM

    OpenAIRE

    Monnier, F.; Vallet, B; B. Soheilian

    2012-01-01

    3D reconstruction of trees is of great interest in large-scale 3D city modelling. Laser scanners provide geometrically accurate 3D point clouds that are very useful for object recognition in complex urban scenes. Trees often cause important occlusions on building façades. Their recognition can lead to occlusion maps that are useful for many façade oriented applications such as visual based localisation and automatic image tagging. This paper proposes a pipeline to detect trees in poi...

  19. A precision of the sequential change point detection

    OpenAIRE

    Ochman-Gozdek, A.; Sarnowski, W; Szajowski, K. J.

    2014-01-01

    A random sequence having two segments being the homogeneous Markov processes is registered. Each segment has his own transition probability law and the length of the segment is unknown and random. The transition probabilities of each process are known and a priori distribution of the disorder moment is given. The decision maker aim is to detect the moment of the transition probabilities change. The detection of the disorder rarely is precise. The decision maker accepts some deviation in estim...

  20. Single and Multiple Change Point Detection in Spike Trains: Comparison of Different CUSUM Methods

    Science.gov (United States)

    Koepcke, Lena; Ashida, Go; Kretzberg, Jutta

    2016-01-01

    In a natural environment, sensory systems are faced with ever-changing stimuli that can occur, disappear or change their properties at any time. For the animal to react adequately the sensory systems must be able to detect changes in external stimuli based on its neuronal responses. Since the nervous system has no prior knowledge of the stimulus timing, changes in stimulus need to be inferred from the changes in neuronal activity, in particular increase or decrease of the spike rate, its variability, and shifted response latencies. From a mathematical point of view, this problem can be rephrased as detecting changes of statistical properties in a time series. In neuroscience, the CUSUM (cumulative sum) method has been applied to recorded neuronal responses for detecting a single stimulus change. Here, we investigate the applicability of the CUSUM approach for detecting single as well as multiple stimulus changes that induce increases or decreases in neuronal activity. Like the nervous system, our algorithm relies exclusively on previous neuronal population activities, without using knowledge about the timing or number of external stimulus changes. We apply our change point detection methods to experimental data obtained by multi-electrode recordings from turtle retinal ganglion cells, which react to changes in light stimulation with a range of typical neuronal activity patterns. We systematically examine how variations of mathematical assumptions (Poisson, Gaussian, and Gamma distributions) used for the algorithms may affect the detection of an unknown number of stimulus changes in our data and compare these CUSUM methods with the standard Rate Change method. Our results suggest which versions of the CUSUM algorithm could be useful for different types of specific data sets. PMID:27445714

  1. NNP Operator's Standing Points Detection from Image Sequence

    International Nuclear Information System (INIS)

    We are carrying out a research to support operator skill evaluation in nuclear power plant BWR operator training facilities. In each training room of the facilities, the video of trainees who are NNP field operators and NPP events are recorded by a multi-media recording system. The video then is utilized for evaluating trainee's skills at training review meetings where the instructors and the trainees check such as whether every operator approaches to the target panel in appropriate timing corresponding to the plant event or alarm occurrence. However, the view from these cameras is not a so comfortable interface and it is difficult for them to estimate trainee's real world position from the video. Our approach is to automatically extract necessary trainee's information from the recorded video sequence for the instructors and trainees to check trainee's behaviors, such as their position and posture. By now, we have proposed a method for automatically extracting trainee's moving path from the video sequence. The moving path is a data sequence of trainee's location in the training room extracted from each video frame. And here we focus on the extraction of trainee's standing points from the extracted moving path data. A standing point is a special location on the moving path where the trainee stops moving for a short period of time. Standing points can give basic information for checking whether a trainee has reached necessary location points and checked the information on the control panel near that location. First of all, we devise the method for removing noise from the moving path data since it is extracted automatically by a tracking system. Kalman filter will be useful for this purpose. For extracting standing points from the smoothed moving path data, we devise the algorithm based on such as the number of frames in which the location of target trainee is not out of a limited area. This paper reports the experimental results such as the location accuracy of the

  2. Homogeneity and change-point detection tests for multivariate data using rank statistics

    CERN Document Server

    Lung-Yut-Fong, Alexandre; Cappé, Olivier

    2011-01-01

    Detecting and locating changes in highly multivariate data is a major concern in several current statistical applications. In this context, the first contribution of the paper is a novel non-parametric two-sample homogeneity test for multivariate data based on the well-known Wilcoxon rank statistic. The proposed two-sample homogeneity test statistic can be extended to deal with ordinal or censored data as well as to test for the homogeneity of more than two samples. The second contribution of the paper concerns the use of the proposed test statistic to perform retrospective change-point analysis. It is first shown that the approach is computationally feasible even when looking for a large number of change-points thanks to the use of dynamic programming. Computable asymptotic $p$-values for the test are then provided in the case where a single potential change-point is to be detected. Compared to available alternatives, the proposed approach appears to be very reliable and robust. This is particularly true in ...

  3. Experimental analysis of the auditory detection process on avian point counts

    Science.gov (United States)

    Simons, T.R.; Alldredge, M.W.; Pollock, K.H.; Wettroth, J.M.

    2007-01-01

    We have developed a system for simulating the conditions of avian surveys in which birds are identified by sound. The system uses a laptop computer to control a set of amplified MP3 players placed at known locations around a survey point. The system can realistically simulate a known population of songbirds under a range of factors that affect detection probabilities. The goals of our research are to describe the sources and range of variability affecting point-count estimates and to find applications of sampling theory and methodologies that produce practical improvements in the quality of bird-census data. Initial experiments in an open field showed that, on average, observers tend to undercount birds on unlimited-radius counts, though the proportion of birds counted by individual observers ranged from 81% to 132% of the actual total. In contrast to the unlimited-radius counts, when data were truncated at a 50-m radius around the point, observers overestimated the total population by 17% to 122%. Results also illustrate how detection distances decline and identification errors increase with increasing levels of ambient noise. Overall, the proportion of birds heard by observers decreased by 28 ?? 4.7% under breezy conditions, 41 ?? 5.2% with the presence of additional background birds, and 42 ?? 3.4% with the addition of 10 dB of white noise. These findings illustrate some of the inherent difficulties in interpreting avian abundance estimates based on auditory detections, and why estimates that do not account for variations in detection probability will not withstand critical scrutiny. ?? The American Ornithologists' Union, 2007.

  4. Feature points detection and tracking based on SIFT combining with KLT method

    Science.gov (United States)

    Wang, Hongbing; Peng, Zhenming; Liu, Jie; Zheng, Youwang; Liao, Baobing; Wang, Yue

    2009-11-01

    For feature point detection with variable scale, rotation, variable illumination and variable 3D view port, a feature point detection and tracking method combining scale invariant feature transform (SIFT) and KLT (Kanade-Lucas-Tomasi) is proposed in this paper. SIFT feature point detection method is improved and it is used to detect feature points of image, and then KLT method is used to track the feature points continuously. In order to verify the feasibility of the proposed method, simulation experiments are carried out in real scene image sequences with different complexity using this method, better results of detection and tracking are obtained and the obtained feature point is more stable than conventional method.

  5. Application of SharePoint Portal Technologies in Public Enterprises

    Directory of Open Access Journals (Sweden)

    Dragan Đokić

    2015-03-01

    Full Text Available Nowadays, systematic reforms are realized acrossmany countries. One of the characteristics of these reforms is necessity for rationalization of expenses in governmental and public enterprises. Rationalization of expenses can be achieved by more extensive application of information and communication technologies based on internet technologies and cloud computing. These systems include huge number of services, applications, resources, users and roles. At the same time, concepts of scalability, availability, ubiquity and pervasiveness need to be applied. This paper deals with application of portal technologies for enhanced content management, document management, and collaboration within public enterprises. The goal is to achieve efficient exchange of information on all hierarchical levels, as well as mechanisms of reporting and performance measurements, such as business intelligence and key performance indicators. The model is based on SharePoint portal technologies. A case study of application within the public enterprise Post of Serbia is described.

  6. Majorization fixed point principle and application to nonlinear integral equations

    CERN Document Server

    Korots, Y V

    2011-01-01

    The successive approximations method allows us to solve problems concerning existence and uniqueness of fixed points of wide classes of operators. The classical result in this field, such as Banach -- Caccioppoli principle together with some its modification and generalisations, is applicable to operators satisfying Lipschitz condition with a small coefficient or, in other words, to operators with the compression property. However, the successive approximations method works well for other classes of operators that are not compressions. In particular, the well known Kantorovich fixed point principle for differentiable operators deals with operators that, in general, are not compression; moreover, this principle covers some cases when Banach -- Caccioppoli principle is nonapplicable. In the article it is presented some modification of Kantorovich fixed point principle that covers nondifferentiable operators. We describe the exact (unimprovable) estimates of the internal and external radius of the domain of exis...

  7. Airborne forward pointing UV Rayleigh lidar for remote clear air turbulence (CAT) detection: system design and performance

    OpenAIRE

    Vrancken, Patrick; Wirth, Martin; Ehret, Gerhard; Barny, Hervé; Rondeau, Philippe; Veerman, Henk

    2016-01-01

    A high-performance airborne UV Rayleigh lidar system was developed within the European project DELICAT. With its forward-pointing architecture it aims at demonstrating a novel detection scheme for clear air turbulence (CAT) for an aeronautics safety application. Due to its occurrence in clear and clean air at high altitudes (aviation cruise flight level), this type of turbulence evades microwave radar techniques and in most cases coherent Doppler lidar techniques. The present lidar detection ...

  8. Tagless and universal biosensor for point detection of pathogens

    Science.gov (United States)

    Markelz, Andrea G.; Knab, Joseph R.; Chen, Jing-Yin; Cerne, John; Cox, William A.

    2004-09-01

    We demonstrate the use of terahertz time domain spectroscopy for determination of ligand binding for biomolecules. Vibrational modes associated with tertiary structure conformational motions lay in the THz frequency range. We examine the THz dielectric response for hen egg white lysozyme (HEWL): free and bound with tri-N-acetyl-D-glucosamine. Transmission measurements on thin films show that there is a small change in the real part of the refractive index as a function of binding and a sizable decrease in the absorbance. A phenomenological model is used to determine the source of the absorbance change. A change in the vibrational mode density of states and net dipole moment changes will necessarily happen for all biomolecule-ligand binding, thus THz dielectric measurements may provide an universally applicable method to determine probe-target binding for biosensor applications.

  9. Detection of Dew-Point by substantial Raman Band Frequency Jumps (A new Method)

    DEFF Research Database (Denmark)

    Hansen, Susanne Brunsgaard; Berg, Rolf W.; Stenby, Erling Halfdan

    Detection of Dew-Point by substantial Raman Band Frequency Jumps (A new Method). See poster at http://www.kemi.dtu.dk/~ajo/rolf/jumps.pdf......Detection of Dew-Point by substantial Raman Band Frequency Jumps (A new Method). See poster at http://www.kemi.dtu.dk/~ajo/rolf/jumps.pdf...

  10. Point pattern match-based change detection in a constellation of previously detected objects

    Energy Technology Data Exchange (ETDEWEB)

    Paglieroni, David W.

    2016-06-07

    A method and system is provided that applies attribute- and topology-based change detection to objects that were detected on previous scans of a medium. The attributes capture properties or characteristics of the previously detected objects, such as location, time of detection, detection strength, size, elongation, orientation, etc. The locations define a three-dimensional network topology forming a constellation of previously detected objects. The change detection system stores attributes of the previously detected objects in a constellation database. The change detection system detects changes by comparing the attributes and topological consistency of newly detected objects encountered during a new scan of the medium to previously detected objects in the constellation database. The change detection system may receive the attributes of the newly detected objects as the objects are detected by an object detection system in real time.

  11. Research Update: Point defects in CdTe{sub x}Se{sub 1−x} crystals grown from a Te-rich solution for applications in detecting radiation

    Energy Technology Data Exchange (ETDEWEB)

    Gul, R.; Roy, U. N.; Bolotnikov, A. E.; Camarda, G. S.; Cui, Y.; Hossain, A.; Yang, G.; James, R. B. [Brookhaven National Laboratory, Upton, New York 11973 (United States); Lee, W. [Korea University, Seoul 136-701 (Korea, Republic of); Cui, Y.; Burger, A. [Fisk University, Nashville, Tennessee 37208 (United States)

    2015-04-01

    We investigated cadmium telluride selenide (CdTeSe) crystals, newly grown by the Traveling Heater Method (THM), for the presence and abundance of point defects. Current Deep Level Transient spectroscopy (I-DLTS) was used to determine the energies of the traps, their capture cross sections, and densities. The bias across the detectors was varied from 1 to 30 V. Four types of point defects were identified, ranging from 10 meV to 0.35 eV. Two dominant traps at energies of 0.18 eV and 0.14 eV were studied in depth. Cd vacancies are found at lower concentrations than other point defects present in the material.

  12. Track before detect for point targets with particle filter in infrared image sequences

    Institute of Scientific and Technical Information of China (English)

    Hongtao Hu; Zhongliang Jing; Shiqiang Hu

    2005-01-01

    @@ The problem of detecting and tracking point targets in a sequence of infrared images with very low signalto-noise ratio (SNR) is investigated in this paper. A track before detect algorithm for infrared (IR) point target is developed based on particle filter. The particle filter is used to estimate the state of the target in track stage. The unnormalized weights of the output of the filter are used to approximately construct the likelihood ratio for hypothesis test in detection stage. Experiment results with the real image sequences that SNR is about 2.0 show that the proposed algorithm can successfully detect and track point target.

  13. Sensitive and reliable detection of Kit point mutation Asp 816 to Val in pathological material

    Directory of Open Access Journals (Sweden)

    Feller Alfred C

    2007-09-01

    Full Text Available Abstract Background Human mastocytosis is a heterogenous disorder which is linked to a gain-of-function mutation in the kinase domain of the receptor tyrosine kinase Kit. This D816V mutation leads to constitutive activation and phosphorylation of Kit with proliferative disorders of mast cells in the peripheral blood, skin, and spleen. Most PCR applications used so far are labour-intensive and are not adopted to daily routine in pathological laboratories. The method has to be robust and working on such different materials like archival formalin-fixed, paraffin-embedded tissue (FFPE and blood samples. Such a method is introduced in this publication. Methods The Kit point mutation Asp 816 to Val is heterozygous which means a problem in detection by PCR because the wild-type allele is also amplified and the number of cells which bear the point mutation is in most of the cases low. Most PCR protocols use probes to block the wild-type allele during amplification with more or less satisfying result. This is why point-mutated forward primers were designed and tested for efficiency in amplification of the mutated allele. Results One primer combination (A fits the most for the introduced PCR assay. It was able just to amplify the mutated allele with high specificity from different patient's materials (FFPE or blood of varying quality and quantity. Moreover, the sensitivity for this assay was convincing because 10 ng of DNA which bears the point mutation could be detected in a total volume of 200 ng of DNA. Conclusion The PCR assay is able to deal with different materials (blood and FFPE this means quality and quantity of DNA and can be used for high-througput screening because of its robustness. Moreover, the method is easy-to-use, not labour-intensive, and easy to realise in a standard laboratory.

  14. Autonomous detection of ISO fade point with color laser printers

    Science.gov (United States)

    Yan, Ni; Maggard, Eric; Fothergill, Roberta; Jessome, Renee J.; Allebach, Jan P.

    2015-01-01

    Image quality assessment is a very important field in image processing. Human observation is slow and subjective, it also requires strict environment setup for the psychological test 1. Thus developing algorithms to match desired human experiments is always in need. Many studies have focused on detecting the fading phenomenon after the materials are printed, that is to monitor the persistence of the color ink 2-4. However, fading is also a common artifact produced by printing systems when the cartridges run low. We want to develop an automatic system to monitor cartridge life and report fading defects when they appear. In this paper, we first describe a psychological experiment that studies the human perspective on printed fading pages. Then we propose an algorithm based on Color Space Projection and K-means clustering to predict the visibility of fading defects. At last, we integrate the psychological experiment result with our algorithm to give a machine learning tool that monitors cartridge life.

  15. Detection of Slope Movement by Comparing Point Clouds Created by SFM Software

    Science.gov (United States)

    Oda, Kazuo; Hattori, Satoko; Takayama, Toko

    2016-06-01

    This paper proposes movement detection method between point clouds created by SFM software, without setting any onsite georeferenced points. SfM software, like Smart3DCaputure, PhotoScan, and Pix4D, are convenient for non-professional operator of photogrammetry, because these systems require simply specification of sequence of photos and output point clouds with colour index which corresponds to the colour of original image pixel where the point is projected. SfM software can execute aerial triangulation and create dense point clouds fully automatically. This is useful when monitoring motion of unstable slopes, or loos rocks in slopes along roads or railroads. Most of existing method, however, uses mesh-based DSM for comparing point clouds before/after movement and it cannot be applied in such cases that part of slopes forms overhangs. And in some cases movement is smaller than precision of ground control points and registering two point clouds with GCP is not appropriate. Change detection method in this paper adopts CCICP (Classification and Combined ICP) algorithm for registering point clouds before / after movement. The CCICP algorithm is a type of ICP (Iterative Closest Points) which minimizes point-to-plane, and point-to-point distances, simultaneously, and also reject incorrect correspondences based on point classification by PCA (Principle Component Analysis). Precision test shows that CCICP method can register two point clouds up to the 1 pixel size order in original images. Ground control points set in site are useful for initial setting of two point clouds. If there are no GCPs in site of slopes, initial setting is achieved by measuring feature points as ground control points in the point clouds before movement, and creating point clouds after movement with these ground control points. When the motion is rigid transformation, in case that a loose Rock is moving in slope, motion including rotation can be analysed by executing CCICP for a loose rock and

  16. Infrared moving point target detection based on spatial-temporal local contrast filter

    Science.gov (United States)

    Deng, Lizhen; Zhu, Hu; Tao, Chao; Wei, Yantao

    2016-05-01

    Infrared moving point target detection is a challenging task. In this paper, we define a novel spatial local contrast (SLC) and a novel temporal local contrast (TLC) to enhance the target's contrast. Based on the defined spatial local contrast and temporal local contrast, we propose a simple but powerful spatial-temporal local contrast filter (STLCF) to detect moving point target from infrared image sequences. In order to verify the performance of spatial-temporal local contrast filter on detecting moving point target, different detection methods are used to detect the target from several infrared image sequences for comparison. The experimental results show that the proposed spatial-temporal local contrast filter has great superiority in moving point target detection.

  17. DETECTING THE GAZING ATTENTION POINTS OF YOUNG AND ELDERLY CYCLISTS.

    Science.gov (United States)

    Uetake, Teruo; Shimoda, Masahiro

    2014-06-01

    This study analyzed the perceived attention represented by "gazing" points of cyclists to expose a latent accidental factor hidden in cyclist behaviour. Eleven elderly people and 23 young people equipped with an eye camera participated in the study. From the camera images, the objects viewed by the cyclists were analyzed. A main road and a community road were used in the experiment. The objects viewed by the cyclists were categorized into nine items that would be indirectly related to the cause of bicycle traffic accidents: gates and porches, parking lots, signals, alleys, other bicycles on the road, pedestrians, signs and painted symbols on the road, schoolyards and houses, and other items. The results of the study indicated that many elderly cyclists always confirmed their safety at alley intersections along both main and community roads, whereas many young people were not so dutiful. The results for unsafe gazing behavior such as looking at a schoolyard or house while cycling were the same for the two groups in that most individuals did not look away from the road while cycling along the main and community roads. Dissimilar results, especially those for alley intersections, resulted from young people not paying due attention to objects, suggesting that such gazing behaviour could be strongly related to traffic accidents involving a bicycle. PMID:26182670

  18. Computer program for analysis of impedance cardiography signals enabling manual correction of points detected automatically

    Science.gov (United States)

    Oleksiak, Justyna; Cybulski, Gerard

    2014-11-01

    The aim of this work was to create a computer program, written in LabVIEW, which enables the visualization and analysis of hemodynamic parameters. It allows the user to import data collected using ReoMonitor, an ambulatory monitoring impedance cardiography (AICG) device. The data include one channel of the ECG and one channel of the first derivative of the impedance signal (dz/dt) sampled at 200Hz and the base impedance signal (Z0) sampled every 8s. The program consist of two parts: a bioscope allowing the presentation of traces (ECG, AICG, Z0) and an analytical portion enabling the detection of characteristic points on the signals and automatic calculation of hemodynamic parameters. The detection of characteristic points in both signals is done automatically, with the option to make manual corrections, which may be necessary to avoid "false positive" recognitions. This application is used to determine the values of basic hemodynamic variables: pre-ejection period (PEP), left ventricular ejection time (LVET), stroke volume (SV), cardiac output (CO), and heart rate (HR). It leaves room for further development of additional features, for both the analysis panel and the data acquisition function.

  19. Detection of trace gas emissions from point sources using shortwave infrared imaging spectrometry

    Science.gov (United States)

    Thorpe, A. K.; Roberts, D. A.; Dennison, P. E.; Bradley, E. S.; Funk, C. C.

    2011-12-01

    Existing spaceborne remote sensing provides an effective means of detecting continental-scale variation in trace gas concentrations, but does not permit mapping of local emissions from point sources. Point source emissions of methane (CH4), nitrous oxide (N2O) and particulates, often associated with combustion and carbon dioxide (CO2) emissions, have significant impacts on air quality. Using Airborne Visible InfraRed Imaging Spectrometer (AVIRIS) data and a cluster-tuned matched filter technique, we have mapped local CH4, N2O and CO2 emissions from terrestrial sources in the Los Angeles basin. CH4 anomalies were in close proximity to known and probable emission sources, including hydrocarbon storage tanks and gas flares. Multiple N2O and CH4 anomalies were detected at a wastewater treatment facility, while CH4 and CO2 anomalies were also identified at a large oil refinery. We discuss ongoing efforts to estimate CH4 concentrations using radiative transfer modeling and potential application of this technique to additional trace gasses with distinct absorption features. This method could be applied to data from existing airborne sensors and planned satellite missions like HyspIRI, thereby improving high resolution mapping of trace gasses and better constraining local sources.

  20. Indoor Navigation from Point Clouds: 3d Modelling and Obstacle Detection

    Science.gov (United States)

    Díaz-Vilariño, L.; Boguslawski, P.; Khoshelham, K.; Lorenzo, H.; Mahdjoubi, L.

    2016-06-01

    In the recent years, indoor modelling and navigation has become a research of interest because many stakeholders require navigation assistance in various application scenarios. The navigational assistance for blind or wheelchair people, building crisis management such as fire protection, augmented reality for gaming, tourism or training emergency assistance units are just some of the direct applications of indoor modelling and navigation. Navigational information is traditionally extracted from 2D drawings or layouts. Real state of indoors, including opening position and geometry for both windows and doors, and the presence of obstacles is commonly ignored. In this work, a real indoor-path planning methodology based on 3D point clouds is developed. The value and originality of the approach consist on considering point clouds not only for reconstructing semantically-rich 3D indoor models, but also for detecting potential obstacles in the route planning and using these for readapting the routes according to the real state of the indoor depictured by the laser scanner.

  1. INDOOR NAVIGATION FROM POINT CLOUDS: 3D MODELLING AND OBSTACLE DETECTION

    Directory of Open Access Journals (Sweden)

    L. Díaz-Vilariño

    2016-06-01

    Full Text Available In the recent years, indoor modelling and navigation has become a research of interest because many stakeholders require navigation assistance in various application scenarios. The navigational assistance for blind or wheelchair people, building crisis management such as fire protection, augmented reality for gaming, tourism or training emergency assistance units are just some of the direct applications of indoor modelling and navigation. Navigational information is traditionally extracted from 2D drawings or layouts. Real state of indoors, including opening position and geometry for both windows and doors, and the presence of obstacles is commonly ignored. In this work, a real indoor-path planning methodology based on 3D point clouds is developed. The value and originality of the approach consist on considering point clouds not only for reconstructing semantically-rich 3D indoor models, but also for detecting potential obstacles in the route planning and using these for readapting the routes according to the real state of the indoor depictured by the laser scanner.

  2. 32 CFR 634.45 - Point system application.

    Science.gov (United States)

    2010-07-01

    .... Violation: Improper overtaking. Points assessed: 3 X. Violation: Other moving violations (involving driver behavior only). Points assessed: 3 Y. Violation: Operating an unsafe vehicle. (See Note 2). Points...

  3. On Approximate Coincidence Point Properties and Their Applications to Fixed Point Theory

    OpenAIRE

    Wei-Shih Du

    2012-01-01

    We first establish some existence results concerning approximate coincidence point properties and approximate fixed point properties for various types of nonlinear contractive maps in the setting of cone metric spaces and general metric spaces. From these results, we present some new coincidence point and fixed point theorems which generalize Berinde-Berinde's fixed point theorem, Mizoguchi-Takahashi's fixed point theorem, and some well-known results in the literature.

  4. Photosensitive point defects in optical glasses: Science and applications

    International Nuclear Information System (INIS)

    The understanding and manipulation of the point defect structure in oxide glasses have been critical to the enhanced performance and reliability of optical-fiber-based, photosensitive photonic devices that currently find widespread application in telecommunications and remote sensing technologies. We provide a brief review of past research investigating photosensitive mechanisms in germanosilicate glasses, the primary material system used in telecommunications fibers. This discussion motivates an overview of ongoing work within our laboratories to migrate photosensitive glass technologies to a planar format for integrated photonic applications. Using reactive-atmosphere, RF-magnetron sputtering, we have demonstrated control of glass defect structure during synthesis, thereby controlling both the material photosensitivity (i.e., dispersion and magnitude of the refractive index change) and its environmental stability

  5. Analgorithmic Framework for Automatic Detection and Tracking Moving Point Targets in IR Image Sequences

    Directory of Open Access Journals (Sweden)

    R. Anand Raji

    2015-05-01

    Full Text Available Imaging sensors operating in infrared (IR region of electromagnetic spectrum are gaining importance in airborne automatic target recognition (ATR applications due to their passive nature of operation. IR imaging sensors exploit the unintended IR radiation emitted by the targets of interest for detection. The ATR systems based on the passive IR imaging sensors employ a set of signal processing algorithms for processing the image information in real-time. The real-time execution of signal processing algorithms provides the sufficient reaction time to the platform carrying ATR system to react upon the target of interest. These set of algorithms include detection, tracking, and classification of low-contrast, small sized-targets. Paper explained a signal processing framework developed to detect and track moving point targets from the acquired IR image sequences in real-time.Defence Science Journal, Vol. 65, No. 3, May 2015, pp.208-213, DOI: http://dx.doi.org/10.14429/dsj.65.8164

  6. On comparison of jump point detection for an exchange rate series

    Institute of Scientific and Technical Information of China (English)

    IP Wai-Cheung; WONG Heung; XIE Zhongjie; LUAN Yihui

    2004-01-01

    The main purpose of this paper is to investigate the detection of jump points of a discontinuous function in the presence of a noise by the wavelet approach. A computing algorithm of our method is proposed and then applied to the daily exchange rate of US Dollar against Deutsche Mark. All the points detected by our method reflect very strong economic and political impacts. Other statistical methods to detect jump points have also been applied to the same exchange rate data. Our proposed method has produced more convincing empirical results than others.

  7. Methodological demonstration of laser beam pointing control for space gravitational wave detection missions

    International Nuclear Information System (INIS)

    In space laser interferometer gravitational wave (G.W.) detection missions, the stability of the laser beam pointing direction has to be kept at 10 nrad/√Hz. Otherwise, the beam pointing jitter noise will dominate the noise budget and make the detection of G.W. impossible. Disturbed by the residue non-conservative forces, the fluctuation of the laser beam pointing direction could be a few μrad/√Hz at frequencies from 0.1 mHz to 10 Hz. Therefore, the laser beam pointing control system is an essential requirement for those space G.W. detection missions. An on-ground test of such beam pointing control system is performed, where the Differential Wave-front Sensing technique is used to sense the beams pointing jitter. An active controlled steering mirror is employed to adjust the beam pointing direction to compensate the jitter. The experimental result shows that the pointing control system can be used for very large dynamic range up to 5 μrad. At the interested frequencies of space G.W. detection missions, between 1 mHz and 1 Hz, beam pointing stability of 6 nrad/√Hz is achieved

  8. Detection of characteristic eye points in non-ideal light conditions

    Science.gov (United States)

    Wiśniewska, Joanna; Galiński, Grzegorz

    2015-09-01

    Detection of characteristic eye points under challenging light conditions is a non-trivial task. Difficulty of this task increase even more when low resolution images are used. This article introduces an adaptive solution for detection of characteristic eye points in mentioned conditions. First, light normalization algorithm is performed. Then, face and eye detection followed by determination of eye status (namely: open or closed) is done. Finally, an adaptive method for pupil and eye corners detection is developed by comparing some existing methods. Experimental results show the outperformance of the proposed method.

  9. Wireless Integrated Biosensors for Point-of-Care Diagnostic Applications

    Directory of Open Access Journals (Sweden)

    Ebrahim Ghafar-Zadeh

    2015-02-01

    Full Text Available Recent advances in integrated biosensors, wireless communication and power harvesting techniques are enticing researchers into spawning a new breed of point-of-care (POC diagnostic devices that have attracted significant interest from industry. Among these, it is the ones equipped with wireless capabilities that drew our attention in this review paper. Indeed, wireless POC devices offer a great advantage, that of the possibility of exerting continuous monitoring of biologically relevant parameters, metabolites and other bio-molecules, relevant to the management of various morbid diseases such as diabetes, brain cancer, ischemia, and Alzheimer’s. In this review paper, we examine three major categories of miniaturized integrated devices, namely; the implantable Wireless Bio-Sensors (WBSs, the wearable WBSs and the handheld WBSs. In practice, despite the aforesaid progress made in developing wireless platforms, early detection of health imbalances remains a grand challenge from both the technological and the medical points of view. This paper addresses such challenges and reports the state-of-the-art in this interdisciplinary field.

  10. Real time change-point detection in a nonlinear quantile model

    OpenAIRE

    Ciuperca, Gabriela

    2016-01-01

    Most studies in real time change-point detection either focus on the linear model or use the CUSUM method under classical assumptions on model errors. This paper considers the sequential change-point detection in a nonlinear quantile model. A test statistic based on the CUSUM of the quantile process subgradient is proposed and studied. Under null hypothesis that the model does not change, the asymptotic distribution of the test statistic is determined. Under alternative hypothesis that at som...

  11. Hierarchical Outlier Detection for Point Cloud Data Using a Density Analysis Method

    OpenAIRE

    Zhu, Junfeng; Hu, Xiangyun; Zhang, Zuxun; XIONG Xiaodong

    2015-01-01

    Laser scanning and image matching are both effective ways to get dense point cloud data, however, outliers obtained from both ways are still inevitable. A novel hierarchical outlier detection method is proposed for the automatic outlier detection of point cloud from image matching and airborne laser scanning. There are two main steps in this method. Firstly, the hierarchical density estimation is used to remove single and small cluster outliers. Then a progressive TIN method is used to find n...

  12. PECVD Chamber Cleaning End Point Detection (EPD) Using Optical Emission Spectroscopy Data

    OpenAIRE

    Sang Jeen Hong; Ho Jae Lee; Dongsun Seo; Gary S. May

    2013-01-01

    In-situ optical emission spectroscopy (OES) is employed for PECVD chamber monitoring. OES is used as an addonsensor to monitoring and cleaning end point detection (EPD). On monitoring plasma chemistry using OES, theprocess gas and by-product gas are simultaneously monitored. Principal component analysis (PCA) enhances thecapability of end point detection using OES data. Through chamber cleaning monitoring using OES, cleaning time isreduced by 53%, in general. Therefore, the gas usage of fluor...

  13. Point Cloud Based Change Detection - an Automated Approach for Cloud-based Services

    Science.gov (United States)

    Collins, Patrick; Bahr, Thomas

    2016-04-01

    The fusion of stereo photogrammetric point clouds with LiDAR data or terrain information derived from SAR interferometry has a significant potential for 3D topographic change detection. In the present case study latest point cloud generation and analysis capabilities are used to examine a landslide that occurred in the village of Malin in Maharashtra, India, on 30 July 2014, and affected an area of ca. 44.000 m2. It focuses on Pléiades high resolution satellite imagery and the Airbus DS WorldDEMTM as a product of the TanDEM-X mission. This case study was performed using the COTS software package ENVI 5.3. Integration of custom processes and automation is supported by IDL (Interactive Data Language). Thus, ENVI analytics is running via the object-oriented and IDL-based ENVITask API. The pre-event topography is represented by the WorldDEMTM product, delivered with a raster of 12 m x 12 m and based on the EGM2008 geoid (called pre-DEM). For the post-event situation a Pléiades 1B stereo image pair of the AOI affected was obtained. The ENVITask "GeneratePointCloudsByDenseImageMatching" was implemented to extract passive point clouds in LAS format from the panchromatic stereo datasets: • A dense image-matching algorithm is used to identify corresponding points in the two images. • A block adjustment is applied to refine the 3D coordinates that describe the scene geometry. • Additionally, the WorldDEMTM was input to constrain the range of heights in the matching area, and subsequently the length of the epipolar line. The "PointCloudFeatureExtraction" task was executed to generate the post-event digital surface model from the photogrammetric point clouds (called post-DEM). Post-processing consisted of the following steps: • Adding the geoid component (EGM 2008) to the post-DEM. • Pre-DEM reprojection to the UTM Zone 43N (WGS-84) coordinate system and resizing. • Subtraction of the pre-DEM from the post-DEM. • Filtering and threshold based classification of

  14. Interest Point Detection for Multispectral Remote Sensing Image Using Phase Congruency in Illumination Space

    Directory of Open Access Journals (Sweden)

    CHEN Min

    2016-02-01

    Full Text Available A robust interest point detection algorithm based on illumination space and phase congruency is proposed in this paper. Firstly, image illumination space is constructed by using a parameters adaptive method. Secondly, a phase congruency based interest point detection algorithm is adopted to compute candidate points in illumination space. Then, all interest point candidates are mapped back to the original image and a non-maximum suppression step is added to find final interest points. Finally, the feature scale values of all interest points are calculated based on the Laplacian function. The proposed algorithm combines the advantages of illumination space and phase congruency, which makes the proposed method robust to the radiation variation of multispectral images. The experimental results show that the proposed method performs better than other traditional methods in feature repeatability rate and repeated features number.

  15. Origin of electrical signals for plasma etching end point detection: Comparison of end point signals and electron density

    International Nuclear Information System (INIS)

    Electrical signals are used for end point detection in plasma etching, but the origin of the electrical changes observed at end point is not well understood. As an etch breaks through one layer and exposes an underlayer, the fluxes and densities of etch products and reactants in the gas phase will change. The resulting perturbation in gas composition may alter the plasma electron density, which in turn may affect the electrical signals. Alternatively, changes in substrate electrical properties or surface properties, such as work function or emitted electron yield, may be involved. To investigate these effects, experiments were performed in a radio-frequency (rf)-biased, inductively coupled reactor, during CF4/Ar plasma etching of silicon dioxide films on silicon substrates. A complete set of electrical parameters, for the bias as well as the inductive source, was measured and compared. The most useful end point signal was found to be the fundamental rf bias impedance, which decreases when the oxide is removed. A simultaneous increase in plasma electron density was measured by a wave cutoff probe. Analytical sheath models indicate that the measured change in electron density accounts for nearly all of the impedance decrease. The change in electron density can in turn be explained by the effects of etch products or reactants on gas composition. In contrast, electrons emitted from the wafer surface play at most a minor role in the changes in electron density and impedance observed at end point.

  16. Video motion detection for physical security applications

    International Nuclear Information System (INIS)

    Physical security specialists have been attracted to the concept of video motion detection for several years. Claimed potential advantages included additional benefit from existing video surveillance systems, automatic detection, improved performance compared to human observers, and cost-effectiveness. In recent years, significant advances in image-processing dedicated hardware and image analysis algorithms and software have accelerated the successful application of video motion detection systems to a variety of physical security applications. Early video motion detectors (VMDs) were useful for interior applications of volumetric sensing. Success depended on having a relatively well-controlled environment. Attempts to use these systems outdoors frequently resulted in an unacceptable number of nuisance alarms. Currently, Sandia National Laboratories (SNL) is developing several advanced systems that employ image-processing techniques for a broader set of safeguards and security applications. The Target Cueing and Tracking System (TCATS), the Video Imaging System for Detection, Tracking, and Assessment (VISDTA), the Linear Infrared Scanning Array (LISA); the Mobile Intrusion Detection and Assessment System (MIDAS), and the Visual Artificially Intelligent Surveillance (VAIS) systems are described briefly

  17. Clinical Observation on Senile Patients with Impaired Glucose Tolerance Treated by Point Application

    Institute of Scientific and Technical Information of China (English)

    Wu Yuquan; Fei Mingfeng; He Yongsheng; Zhang Cunhai; Zheng Wei; Wu Yajun; Li Weihong

    2006-01-01

    In order to observe and evaluate the therapeutic effects of point application on senile impaired glucose tolerance (IGT), 64 senile IGT patients were randomly divided into two groups with 32 cases in each group.The control group was treated with interference therapy of controlling diet, while the observation group was given point application at Yishu (胰俞 1.5 cun lateral to the Du Channel, at the level of the lower border of the spinous process of the eighth thoracic vertebra), Pishu (BL 20), Sanyinjiao (SP 6), Zusanli (ST 36) and other points in addition to interference therapy of controlling diet. After 2 courses of treatment, the postprandial blood sugar was detected. As a result, the postprandial blood sugar obviously reduced in both groups (P<0.05, P<0.01) with a lower level in the observation group than in the control group (P<0.05), indicating that point application in combination with interference therapy of controlling diet has a reliable therapeutic effect on senile IGT patients.

  18. Hierarchical Outlier Detection for Point Cloud Data Using a Density Analysis Method

    Directory of Open Access Journals (Sweden)

    ZHU Junfeng

    2015-03-01

    Full Text Available Laser scanning and image matching are both effective ways to get dense point cloud data, however, outliers obtained from both ways are still inevitable. A novel hierarchical outlier detection method is proposed for the automatic outlier detection of point cloud from image matching and airborne laser scanning. There are two main steps in this method. Firstly, the hierarchical density estimation is used to remove single and small cluster outliers. Then a progressive TIN method is used to find non-outliers removed in the previous steps. The experimental results indicate the effectiveness of this method in dealing with the two types of points cloud data. And this method can also handle low quality point cloud data from image matching. The quantitative analysis shows that the outlier detection rate is higher than 97%.

  19. Automated Detection of Geomorphic Features in LiDAR Point Clouds of Various Spatial Density

    Science.gov (United States)

    Dorninger, Peter; Székely, Balázs; Zámolyi, András.; Nothegger, Clemens

    2010-05-01

    extraction and modeling of buildings (Dorninger & Pfeifer, 2008) we expected that similar generalizations for geomorphic features can be achieved. Our aim is to recognize as many features as possible from the point cloud in the same processing loop, if they can be geometrically described with appropriate accuracy (e.g., as a plane). For this, we propose to apply a segmentation process allowing determining connected, planar structures within a surface represented by a point cloud. It is based on a robust determination of local tangential planes for all points acquired (Nothegger & Dorninger, 2009). It assumes that for points, belonging to a distinct planar structure, similar tangential planes can be determined. In passing, points acquired at continuous such as vegetation can be identified and eliminated. The plane parameters are used to define a four-dimensional feature space which is used to determine seed-clusters globally for the whole are of interest. Starting from these seeds, all points defining a connected, planar region are assigned to a segment. Due to the design of the algorithm, millions of input points can be processed with acceptable processing time on standard computer systems. This allows for processing geomorphically representative areas at once. For each segment, numerous parameter are derived which can be used for further exploitation. These are, for example, location, area, aspect, slope, and roughness. To prove the applicability of our method for automated geomorphic terrain analysis, we used terrestrial and airborne laser scanning data, acquired at two locations. The data of the Doren landslide located in Vorarlberg, Austria, was acquired by a terrestrial Riegl LS-321 laser scanner in 2008, by a terrestrial Riegl LMS-Z420i laser scanner in 2009, and additionally by three airborne LiDAR measurement campaigns, organized by the Landesvermessungsamt Vorarlberg, Feldkirch, in 2003, 2006, and 2007. The measurement distance of the terrestrial measurements was

  20. Feature Point Method of Chinese Character Recognition and Its Application

    Institute of Scientific and Technical Information of China (English)

    张Xin中; 闫昌德; 等

    1990-01-01

    A new method for recognizing Chinese characters is proposed.It is based on the so-called feature points of Chinese characters.The feature points we use include those on the stroke of a character.i.e.,end points.turning points,fork points and cross points.and the key points on the background of character.This method differs from the previous ones for it combines the feature points on stroke with those on background and it uses feature points to recognize Chinese characters directly.A Chinese character recognition system based to top-down dynamical matching of feature point is developed.The system can recognize not only 6763 printed sample Song font Chinese characters of size 5.6×5.6mm2 with high recognition rate,but also the general printed books,magazines and documents with a satisfactory recognition rate and speed.

  1. Airborne forward pointing UV Rayleigh lidar for remote clear air turbulence (CAT) detection: system design and performance

    CERN Document Server

    Vrancken, Patrick; Ehret, Gerhard; Barny, Hervé; Rondeau, Philippe; Veerman, Henk

    2016-01-01

    A high-performance airborne UV Rayleigh lidar system was developed within the European project DELICAT. With its forward-pointing architecture it aims at demonstrating a novel detection scheme for clear air turbulence (CAT) for an aeronautics safety application. Due to its occurrence in clear and clean air at high altitudes (aviation cruise flight level), this type of turbulence evades microwave radar techniques and in most cases coherent Doppler lidar techniques. The present lidar detection technique relies on air density fluctuations measurement and is thus independent of backscatter from hydrometeors and aerosol particles. The subtle air density fluctuations caused by the turbulent air flow demand exceptionally high stability of the setup and in particular of the detection system. This paper describes an airborne test system for the purpose of demonstrating this technology and turbulence detection method: a high-power UV Rayleigh lidar system is installed on a research aircraft in a forward-looking configu...

  2. Magnetic gradiometer for underwater detection applications

    Science.gov (United States)

    Kumar, S.; Skvoretz, D. C.; Moeller, C. R.; Ebbert, M. J.; Perry, A. R.; Ostrom, R. K.; Tzouris, A.; Bennett, S. L.; Czipott, P. V.; Sulzberger, G.; Allen, G. I.; Bono, J.; Clem, T. R.

    2006-05-01

    We have designed and constructed a magnetic gradiometer for underwater mine detection, location and tracking. The United States Naval Surface Warfare Center (NSWC PC) in Panama City, FL has conducted sea tests of the system using an unmanned underwater vehicle (UUV). The Real-Time Tracking Gradiometer (RTG) measures the magnetic field gradients caused by the presence of a mine in the Earth's magnetic field. These magnetic gradients can then be used to detect and locate a target with the UUV in motion. Such a platform can also be used for other applications, including the detection and tracking of vessels and divers for homeland (e.g., port) security and the detection of underwater pipelines. Data acquired by the RTG in sea tests is presented in this paper.

  3. Biomedical applications of single molecule detection

    Science.gov (United States)

    Kelso, D. M.

    1997-05-01

    The search for increased sensitivity of bio-analytical techniques has recently shifted from signal generation to detection. While enzyme amplifiers and chemiluminescent reporters developed by chemists over the last two decades gradually moved detection limits to the attomol level, it has taken engineers only a few years to reach single- molecule sensitivity with the development of new instrumentation. A number of different approaches have successfully achieved single-molecule fluorescence detection including confocal and near-field scanning optical microscopy, photon-counting cameras, fluorescence- correlation and time-gated spectroscopy. They detect labels immobilized on substrates, diffusing in solution and flowing in electro-osmotic and hydrodynamically focused streams. Biotechnology has created numerous application s for single- molecule detection. In research labs, it can dramatically increase the rate of DNA sequencing, screen libraries for products of directed evolution, and characterize compounds in drug discovery programs. In medical diagnostics, ultra- sensitive detection technologies can be used for genetic screening, detection of infectious diseases, or multi- analyte profiles. It can be applied to immunoassays as well as DNA or RNA hybridization assays.

  4. The future point-of-care detection of disease and its data capture and handling.

    Science.gov (United States)

    Lopez-Barbosa, Natalia; Gamarra, Jorge D; Osma, Johann F

    2016-04-01

    Point-of-care detection is a widely studied area that attracts effort and interest from a large number of fields and companies. However, there is also increased interest from the general public in this type of device, which has driven enormous changes in the design and conception of these developments and the way data is handled. Therefore, future point-of-care detection has to include communication with front-end technology, such as smartphones and networks, automation of manufacture, and the incorporation of concepts like the Internet of Things (IoT) and cloud computing. Three key examples, based on different sensing technology, are analyzed in detail on the basis of these items to highlight a route for the future design and development of point-of-care detection devices and their data capture and handling. PMID:26780711

  5. Decision tree learning for detecting turning points in business process orientation: a case of Croatian companies

    Directory of Open Access Journals (Sweden)

    Ljubica Milanović Glavan

    2015-03-01

    Full Text Available Companies worldwide are embracing Business Process Orientation (BPO in order to improve their overall performance. This paper presents research results on key turning points in BPO maturity implementation efforts. A key turning point is defined as a component of business process maturity that leads to the establishment and expansion of other factors that move the organization to the next maturity level. Over the past few years, different methodologies for analyzing maturity state of BPO have been developed. The purpose of this paper is to investigate the possibility of using data mining methods in detecting key turning points in BPO. Based on survey results obtained in 2013, the selected data mining technique of classification and regression trees (C&RT was used to detect key turning points in Croatian companies. These findings present invaluable guidelines for any business that strives to achieve more efficient business processes.

  6. Urban Road Detection in Airbone Laser Scanning Point Cloud Using Random Forest Algorithm

    Science.gov (United States)

    Kaczałek, B.; Borkowski, A.

    2016-06-01

    The objective of this research is to detect points that describe a road surface in an unclassified point cloud of the airborne laser scanning (ALS). For this purpose we use the Random Forest learning algorithm. The proposed methodology consists of two stages: preparation of features and supervised point cloud classification. In this approach we consider ALS points, representing only the last echo. For these points RGB, intensity, the normal vectors, their mean values and the standard deviations are provided. Moreover, local and global height variations are taken into account as components of a feature vector. The feature vectors are calculated on a basis of the 3D Delaunay triangulation. The proposed methodology was tested on point clouds with the average point density of 12 pts/m2 that represent large urban scene. The significance level of 15% was set up for a decision tree of the learning algorithm. As a result of the Random Forest classification we received two subsets of ALS points. One of those groups represents points belonging to the road network. After the classification evaluation we achieved from 90% of the overall classification accuracy. Finally, the ALS points representing roads were merged and simplified into road network polylines using morphological operations.

  7. A Software Application to Detect Dental Color

    Directory of Open Access Journals (Sweden)

    Dan SÎMPĂLEAN

    2015-09-01

    Full Text Available Choosing dental color for missing teeth or tooth reconstruction is an important step and it usually raises difficulties for dentists due to a significant amount of subjective factors that can influence the color selection. Dental reconstruction presumes the combination between dentistry and chromatics, thus implying important challenges. Purpose: The aim of this study was to develop and implement a software application for detecting dental color to come to the aid of dentists and largely to remove the inherent subjectiveness of the human vision. Basic Methods: The implemented application was named Color Detection and the application’s source code is written using the C++ language. During application development, for creating the GUI (graphical user interface the wxWidgets 2.8 library it was used. Results: The application displays the average color of the selected area of interest, the reference color from the key collection existent in the program and also the degree of similarity between the original (the selected area of interest and the nearest reference key. This degree of similarity is expressed as a percentage. Conclusions: The Color Detection Program, by eliminating the subjectivity inherent to human sight, can help the dentist to select an appropriate dental color with precision.

  8. Novel Spatiotemporal Filter for Dim Point Targets Detection in Infrared Image Sequences

    Directory of Open Access Journals (Sweden)

    Zhaohui Li

    2015-01-01

    Full Text Available Dim point target detection is of great importance in both civil and military fields. In this paper a novel spatiotemporal filter is proposed to incorporate both the spatial and temporal features of moving dim point targets. Since targets are expected to be detected as far as possible, in this situation, they have no texture features in spatial dimensions, appearing like isolated points. Based on the attributes, potential targets are extracted by searching the local maximum point in a sliding window. And the potential targets are then correlated based on target moving patterns. After combining local maximum points and target moving patterns, structure background in infrared scene is removed. Next, the temporal profiles of infrared sense are reviewed and examined. By a new max-median filter performing on temporal profiles, the intensity of target pulse signal is extracted. Finally, each temporal profile is divided into several pieces to estimate the variance of the temporal profiles, which leads to a new detection metric. The proposed approach is tested via several infrared image sequences. The results show that our proposed method can significantly reduce the complex background in aerial infrared image sequence and have a good detection performance.

  9. Detection of gaseous heavy water leakage points in CANDU 6 pressurized heavy water reactors

    International Nuclear Information System (INIS)

    During reactor operation, the heavy water filled primary coolant system in a CANDU 6 Pressurized Heavy Water (PHWR) may leak through routine operations of the plant via components, mechanical joints, and during inadvertent operations etc. Early detection of leak points is therefore important to maintain plant safety and economy. There are many independent systems to monitor and recover heavy water leakage in a CANDU 6 PHWR. Methodology for early detection based on operating experience from these systems, is investigated in this paper. In addition, the four symptoms of D2O leakage, the associated process for clarifying and verifying the leakage, and the probable points of leakage are discussed. (author)

  10. Change-Point Detection in Time-Series Data by Relative Density-Ratio Estimation

    CERN Document Server

    Liu, Song; Collier, Nigel; Sugiyama, Masashi

    2012-01-01

    The objective of change-point detection is to discover abrupt property changes lying behind time series data. In this paper, we present a novel statistical change-point detection algorithm that is based on non-parametric divergence estimation between two retrospective segments. Our method uses the relative Pearson divergence as a divergence measure, and it is accurately and efficiently estimated by a method of direct density-ratio estimation. Through experiments on artificial and real-world datasets including human-activity sensing, speeches, and Twitter archives, we demonstrate the usefulness of the proposed method.

  11. Traffic sign detection in MLS acquired point clouds for geometric and image-based semantic inventory

    Science.gov (United States)

    Soilán, Mario; Riveiro, Belén; Martínez-Sánchez, Joaquín; Arias, Pedro

    2016-04-01

    Nowadays, mobile laser scanning has become a valid technology for infrastructure inspection. This technology permits collecting accurate 3D point clouds of urban and road environments and the geometric and semantic analysis of data became an active research topic in the last years. This paper focuses on the detection of vertical traffic signs in 3D point clouds acquired by a LYNX Mobile Mapper system, comprised of laser scanning and RGB cameras. Each traffic sign is automatically detected in the LiDAR point cloud, and its main geometric parameters can be automatically extracted, therefore aiding the inventory process. Furthermore, the 3D position of traffic signs are reprojected on the 2D images, which are spatially and temporally synced with the point cloud. Image analysis allows for recognizing the traffic sign semantics using machine learning approaches. The presented method was tested in road and urban scenarios in Galicia (Spain). The recall results for traffic sign detection are close to 98%, and existing false positives can be easily filtered after point cloud projection. Finally, the lack of a large, publicly available Spanish traffic sign database is pointed out.

  12. Fault Detection and Diagnosis of Railway Point Machines by Sound Analysis.

    Science.gov (United States)

    Lee, Jonguk; Choi, Heesu; Park, Daihee; Chung, Yongwha; Kim, Hee-Young; Yoon, Sukhan

    2016-01-01

    Railway point devices act as actuators that provide different routes to trains by driving switchblades from the current position to the opposite one. Point failure can significantly affect railway operations, with potentially disastrous consequences. Therefore, early detection of anomalies is critical for monitoring and managing the condition of rail infrastructure. We present a data mining solution that utilizes audio data to efficiently detect and diagnose faults in railway condition monitoring systems. The system enables extracting mel-frequency cepstrum coefficients (MFCCs) from audio data with reduced feature dimensions using attribute subset selection, and employs support vector machines (SVMs) for early detection and classification of anomalies. Experimental results show that the system enables cost-effective detection and diagnosis of faults using a cheap microphone, with accuracy exceeding 94.1% whether used alone or in combination with other known methods. PMID:27092509

  13. Point source detection performance of Hard X-ray Modulation Telescope imaging observation

    CERN Document Server

    Huo, Zhuoxi; Li, Xiaobo; Zhou, Jianfeng

    2015-01-01

    The Hard X-ray Modulation Telescope (HXMT) will perform an all-sky survey in hard X-ray band as well as deep imaging of a series of small sky regions. We expect various compact objects to be detected in these imaging observations. Point source detection performance of HXMT imaging observation depends not only on the instrument but also on its data analysis since images are reconstructed from HXMT observed data with numeric methods. Denoising technique plays an import part in HXMT imaging data analysis pipeline alongside with demodulation and source detection. In this paper we have implemented several methods for denoising HXMT data and evaluated the point source detection performances in terms of sensitivities and location accuracies. The results show that direct demodulation with 1-fold cross correlation should be the default reconstruction and regularization methods, although both sensitivity and location accuracy could be further imporved by selecting and tuning numerical methods in data analysis of HXMT i...

  14. Fault Detection and Diagnosis of Railway Point Machines by Sound Analysis

    Directory of Open Access Journals (Sweden)

    Jonguk Lee

    2016-04-01

    Full Text Available Railway point devices act as actuators that provide different routes to trains by driving switchblades from the current position to the opposite one. Point failure can significantly affect railway operations, with potentially disastrous consequences. Therefore, early detection of anomalies is critical for monitoring and managing the condition of rail infrastructure. We present a data mining solution that utilizes audio data to efficiently detect and diagnose faults in railway condition monitoring systems. The system enables extracting mel-frequency cepstrum coefficients (MFCCs from audio data with reduced feature dimensions using attribute subset selection, and employs support vector machines (SVMs for early detection and classification of anomalies. Experimental results show that the system enables cost-effective detection and diagnosis of faults using a cheap microphone, with accuracy exceeding 94.1% whether used alone or in combination with other known methods.

  15. Fiducial points extraction and charactericwaves detection in ECG signal using a model-based bayesian framework

    OpenAIRE

    Akhbari, Mahsa; Shamsollahi, Mohammad,; Jutten, Christian

    2013-01-01

    International audience The automatic detection of Electrocardiogram (ECG) waves is important to cardiac disease diagnosis. A good perfor- mance of an automatic ECG analyzing system depends heavily upon the accurate and reliable detection of QRS complex, as well as P and T waves. In this paper, we propose an efficient method for extraction of characteristic points of ECG signal. The method is based on a nonlinear dynamic model, previously introduced for generation of synthetic ECG signals. ...

  16. The uniformly most powerful invariant test for two models of detection function in point transect sampling

    OpenAIRE

    Riccardo Borgoni; Piero Quatto

    2013-01-01

    Estimating population abundance is of primary interest in wildlife population studies. Point transect sampling is a well established methodology for this purpose. The usual approach for estimating the density or the size of the population of interest is to assume a particular model for the detection function (the conditional probability of detecting an animal given that it is at a certain distance from the observer). Two popular models for this function are the half-normal model and the negat...

  17. Zeolite fiber integrated microsensors for highly sensitive point detection of chemical agents

    Science.gov (United States)

    Liu, Ning; Hui, Juan; Dong, Junhang; Xiao, Hai

    2006-05-01

    A zeolite-fiber integrated chemical sensor was developed for in situ point detection of chemical warfare agents. The sensor was made by fine-polishing the MFI polycrystalline zeolite thin film synthesized on the endface of the single mode optical fiber. The sensor device operates by measuring the optical thickness changes of the zeolite thin film caused by the adsorption of analytes into the zeolite channels. The sensor was demonstrated for sensitive detection of toluene and dimethyl methylphosphonate (DMMP).

  18. Metal-oxide-metal point contact junction detectors. [detection mechanism and mechanical stability

    Science.gov (United States)

    Baird, J.; Havemann, R. H.; Fults, R. D.

    1973-01-01

    The detection mechanism(s) and design of a mechanically stable metal-oxide-metal point contact junction detector are considered. A prototype for a mechanically stable device has been constructed and tested. A technique has been developed which accurately predicts microwave video detector and heterodyne mixer SIM (semiconductor-insulator-metal) diode performance from low dc frequency volt-ampere curves. The difference in contact potential between the two metals and geometrically induced rectification constitute the detection mechanisms.

  19. Biomedical tritium applications with AMS detection

    International Nuclear Information System (INIS)

    There are numerous applications for tritium (3 H) as a tracer isotope in biomedicine commonly combined with liquid scintillation counting method. The use of accelerator mass spectrometry (AMS), a rather new detection method will, enlarge and open new possibilities for tritium applications in biomedicine, especially when sample volumes are small. The tritium in the samples has to be transformed to solid form, which yields a high output of negative hydrogen ion current. The sample preparation is done in two steps: firstly extracting water from the biological sample and secondly, extracting hydrogen/tritium from the water and forming a chemically suitable compound for the AMS ion source. In this paper a chemical for the sample preparation is described. The results of the first measurements of tritiated water with known activity using the AMS detection technique will also be presented.(authors)

  20. Iterative Schemes for Zero Points of Maximal Monotone Operators and Fixed Points of Nonexpansive Mappings and Their Applications

    Directory of Open Access Journals (Sweden)

    Yeol Je Cho

    2008-03-01

    Full Text Available Two iterative schemes for finding a common element of the set of zero points of maximal monotone operators and the set of fixed points of nonexpansive mappings in the sense of Lyapunov functional in a real uniformly smooth and uniformly convex Banach space are obtained. Two strong convergence theorems are obtained which extend some previous work. Moreover, the applications of the iterative schemes are demonstrated.

  1. Automatic refinement of parallel applications structure detection

    OpenAIRE

    González, Juan,; Huck, Kevin; Giménez Lucas, Judit; Labarta Mancho, Jesús José

    2012-01-01

    Analyzing parallel programs has become increasingly difficult due to the immense amount of information collected on large systems. In this scenario, cluster analysis has been proved to be a useful technique to reduce the amount of data to analyze. A good example is the use of the density-based cluster algorithm DBSCAN to identify similar single program multiple data (SPMD) computing phases in message-passing applications. This structure detection simplifies the analyst wo...

  2. Applications of electrochemiluminescence detection on microfabricated devices

    OpenAIRE

    Spehar-Délèze, Anna-Maria

    2006-01-01

    The aim of this thesis was to investigate bioanalytical applications of electrochemiluminescence (ECL), which refers to the generation of light at the surface of an electrode. Two types of ECL detection were studied: anodic ECL and cathodic hot electron-induced ECL (HECL). In anodic ECL light is generated at traditional electrode materials, such as noble metal or carbon, while in cathodic HECL thin insulating film-coated electrodes are used, and light generation is initiated by tunnel emissio...

  3. Clinical Experience in Application of the Point Wangu

    Institute of Scientific and Technical Information of China (English)

    杨西永

    2002-01-01

    Wangu (GB 12) is a point of the Gallbladder Channel of Foot Shaoyang, located in the depression posteroinferior to the temporal process. And it is a hui point of Foot Taiyang and Shaoyang Channels, with the effects of eliminating pathogenic wind and heat, and tranquilizing the mind. This point is located superior to the attachment point of the sternocleidomastoid muscle, in which there distribute the stem of the lesser occipital nerve, and branches of the posterior auricular artery and vein. It can be needled perpendicularly 0.5-1 cun deep. In clinical practice, the author has applied the point for treatment of various diseases, and obtained quite satisfactory therapeutic results. The following is a report of some illustrative cases.

  4. Sequential change-point detection when unknown parameters are present in the pre-change distribution

    OpenAIRE

    Mei, Yajun

    2006-01-01

    In the sequential change-point detection literature, most research specifies a required frequency of false alarms at a given pre-change distribution fθ and tries to minimize the detection delay for every possible post-change distribution gλ. In this paper, motivated by a number of practical examples, we first consider the reverse question by specifying a required detection delay at a given post-change distribution and trying to minimize the frequency of false alarms for every possible pre-cha...

  5. 16 CFR Figure 5 to Subpart A of... - Zero Reference Point Related to Detecting Plane

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Zero Reference Point Related to Detecting Plane 5 Figure 5 to Subpart A of Part 1209 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION... Plane EC03OC91.035...

  6. Detection potential to point-like neutrino sources with the NEMO-km3 telescope

    OpenAIRE

    Distefano, C.

    2006-01-01

    The NEMO Collaboration is conducting an R&D activity towards the construction of a Mediterranean km3 neutrino telescope. In this work, we present the results of Monte Carlo simulation studies on the capability of the proposed NEMO telescope to detect and identify point-like sources of high energy muon neutrinos.

  7. Point association analysis of vessel target detection with SAR, HFSWR and AIS

    Institute of Scientific and Technical Information of China (English)

    JI Yonggang; ZHANG Jie; MENG Junmin; WANG Yiming

    2014-01-01

    A space-borne synthetic aperture radar (SAR), a high frequency surface wave radar (HFSWR), and a ship automatic identification system (AIS) are the main remote sensors for vessel monitoring in a wide range. These three sensors have their own advantages and weaknesses, and they can complement each other in some situations. So it would improve the capability of vessel target detection to use multiple sensors in-cluding SAR, HFSWR, and AIS to identify non-cooperative vessel targets from the fusion results. During the fusion process of multiple sensors’ detection results, point association is one of the key steps, and it can affect the accuracy of the data fusion and the efficiency of a non-cooperative target’s recognition. This study investigated the point association analyses of vessel target detection under different conditions: space-borne SAR paired with AIS, as well as HFSWR, paired with AIS , and the characteristics of the SAR and the HFSWR and their capability of vessel target detection. Then a point association method of multiple sensors was proposed. Finally, the thresholds selection of key parameters in the points association (including range threshold, radial velocity threshold, and azimuth threshold) were investigated, and their influences on final association results were analyzed.

  8. CVD diamond for nuclear detection applications

    CERN Document Server

    Bergonzo, P; Tromson, D; Mer, C; Guizard, B; Marshall, R D; Foulon, F

    2002-01-01

    Chemically vapour deposited (CVD) diamond is a remarkable material for the fabrication of radiation detectors. In fact, there exist several applications where other standard semiconductor detectors do not fulfil the specific requirements imposed by corrosive, hot and/or high radiation dose environments. The improvement of the electronic properties of CVD diamond has been under intensive investigations and led to the development of a few applications that are addressing specific industrial needs. Here, we report on CVD diamond-based detector developments and we describe how this material, even though of a polycrystalline nature, is readily of great interest for applications in the nuclear industry as well as for physics experiments. Improvements in the material synthesis as well as on device fabrication especially concern the synthesis of films that do not exhibit space charge build up effects which are often encountered in CVD diamond materials and that are highly detrimental for detection devices. On a pre-i...

  9. Flexible low-cost cardiovascular risk marker biosensor for point-of-care applications

    KAUST Repository

    Sivashankar, S.

    2015-10-22

    The detection and quantification of protein on a laser written flexible substrate for point-of-care applications are described. A unique way of etching gold on polyethylene terephthalate (PET) substrate is demonstrated by reducing the damage that may be caused on PET sheets otherwise. On the basis of the quantity of the C-reactive protein (CRP) present in the sample, the risk of cardiac disease can be assessed. This hsCRP test is incorporated to detect the presence of CRP on a PET laser patterned biosensor. Concentrations of 1, 2, and 10 mg/l were chosen to assess the risk of cardiac diseases as per the limits set by the American Heart Association.

  10. SINGLE TREE DETECTION FROM AIRBORNE LASER SCANNING DATA USING A MARKED POINT PROCESS BASED METHOD

    Directory of Open Access Journals (Sweden)

    J. Zhang

    2013-05-01

    Full Text Available Tree detection and reconstruction is of great interest in large-scale city modelling. In this paper, we present a marked point process model to detect single trees from airborne laser scanning (ALS data. We consider single trees in ALS recovered canopy height model (CHM as a realization of point process of circles. Unlike traditional marked point process, we sample the model in a constraint configuration space by making use of image process techniques. A Gibbs energy is defined on the model, containing a data term which judge the fitness of the model with respect to the data, and prior term which incorporate the prior knowledge of object layouts. We search the optimal configuration through a steepest gradient descent algorithm. The presented hybrid framework was test on three forest plots and experiments show the effectiveness of the proposed method.

  11. Prospects for detecting supersymmetric dark matter at Post-LEP benchmark points

    International Nuclear Information System (INIS)

    A new set of supersymmetric benchmark scenarios has recently been proposed in the context of the constrained MSSM (CMSSM) with universal soft supersymmetry-breaking masses, taking into account the constraints from LEP, b→sγ and gμ-2. These points have previously been used to discuss the physics reaches of different accelerators. In this paper, we discuss the prospects for discovering supersymmetric dark matter in these scenarios. We consider direct detection through spin-independent and spin-dependent nuclear scattering, as well as indirect detection through relic annihilations to neutrinos, photons, and positrons. We find that several of the benchmark scenarios offer good prospects for direct detection via spin-independent nuclear scattering and indirect detection via muons produced by neutrinos from relic annihilations inside the Sun, and some models offer good prospects for detecting photons from relic annihilations in the galactic centre. (orig.)

  12. The combined FSS-SPRT method for detection and tracking of low SNR point targets

    Institute of Scientific and Technical Information of China (English)

    ZHANG Hai-Ying; ZHANG Tian-Wen

    2007-01-01

    For the detection and tracking of dim point targets with SNR <2 dB, the combined SPRT and FSS method is given to accomplish detection in which likelihood testing are carried out twice to prune constantly.Firstly, the SPRT is developed aiming at the heuristic segments formed by correlation analysis. In order to avoid missing detection the threshold is chosen much lower. Secondly, by adding samples and choosing the one most similar to the heuristic segment to make state estimation FSS is implemented. This time we choose a higher threshold. Moreover in preprocessing the compound kernel estimation is designed to depress varying background clutter. Multiple experimental sequences validate that the method is more suitable for the dim targets detection and tracking compared with the scheme choosing the higher intensity pixel in tracking. It not only has perfect detection performance but also can greatly enhance tracking performance.

  13. Road traffic sign detection and classification from mobile LiDAR point clouds

    Science.gov (United States)

    Weng, Shengxia; Li, Jonathan; Chen, Yiping; Wang, Cheng

    2016-03-01

    Traffic signs are important roadway assets that provide valuable information of the road for drivers to make safer and easier driving behaviors. Due to the development of mobile mapping systems that can efficiently acquire dense point clouds along the road, automated detection and recognition of road assets has been an important research issue. This paper deals with the detection and classification of traffic signs in outdoor environments using mobile light detection and ranging (Li- DAR) and inertial navigation technologies. The proposed method contains two main steps. It starts with an initial detection of traffic signs based on the intensity attributes of point clouds, as the traffic signs are always painted with highly reflective materials. Then, the classification of traffic signs is achieved based on the geometric shape and the pairwise 3D shape context. Some results and performance analyses are provided to show the effectiveness and limits of the proposed method. The experimental results demonstrate the feasibility and effectiveness of the proposed method in detecting and classifying traffic signs from mobile LiDAR point clouds.

  14. Point-of-care diagnostics for niche applications.

    Science.gov (United States)

    Cummins, Brian M; Ligler, Frances S; Walker, Glenn M

    2016-01-01

    Point-of-care or point-of-use diagnostics are analytical devices that provide clinically relevant information without the need for a core clinical laboratory. In this review we define point-of-care diagnostics as portable versions of assays performed in a traditional clinical chemistry laboratory. This review discusses five areas relevant to human and animal health where increased attention could produce significant impact: veterinary medicine, space travel, sports medicine, emergency medicine, and operating room efficiency. For each of these areas, clinical need, available commercial products, and ongoing research into new devices are highlighted. PMID:26837054

  15. Hacking point of sale payment application secrets, threats, and solutions

    CERN Document Server

    Gomzin, Slava

    2014-01-01

    Must-have guide for professionals responsible for securing credit and debit card transactions As recent breaches like Target and Neiman Marcus show, payment card information is involved in more security breaches than any other data type. In too many places, sensitive card data is simply not protected adequately. Hacking Point of Sale is a compelling book that tackles this enormous problem head-on. Exploring all aspects of the problem in detail - from how attacks are structured to the structure of magnetic strips to point-to-point encryption, and more - it's packed with practical recommendati

  16. Some Fixed Point Theorems on Ordered Metric Spaces and Application

    Directory of Open Access Journals (Sweden)

    Altun Ishak

    2010-01-01

    Full Text Available We present some fixed point results for nondecreasing and weakly increasing operators in a partially ordered metric space using implicit relations. Also we give an existence theorem for common solution of two integral equations.

  17. D Geological Outcrop Characterization: Automatic Detection of 3d Planes (azimuth and Dip) Using LiDAR Point Clouds

    Science.gov (United States)

    Anders, K.; Hämmerle, M.; Miernik, G.; Drews, T.; Escalona, A.; Townsend, C.; Höfle, B.

    2016-06-01

    Terrestrial laser scanning constitutes a powerful method in spatial information data acquisition and allows for geological outcrops to be captured with high resolution and accuracy. A crucial aspect for numerous geologic applications is the extraction of rock surface orientations from the data. This paper focuses on the detection of planes in rock surface data by applying a segmentation algorithm directly to a 3D point cloud. Its performance is assessed considering (1) reduced spatial resolution of data and (2) smoothing in the course of data pre-processing. The methodology is tested on simulations of progressively reduced spatial resolution defined by varying point cloud density. Smoothing of the point cloud data is implemented by modifying the neighborhood criteria during normals estima-tion. The considerable alteration of resulting planes emphasizes the influence of smoothing on the plane detection prior to the actual segmentation. Therefore, the parameter needs to be set in accordance with individual purposes and respective scales of studies. Fur-thermore, it is concluded that the quality of segmentation results does not decline even when the data volume is significantly reduced down to 10%. The azimuth and dip values of individual segments are determined for planes fit to the points belonging to one segment. Based on these results, azimuth and dip as well as strike character of the surface planes in the outcrop are assessed. Thereby, this paper contributes to a fully automatic and straightforward workflow for a comprehensive geometric description of outcrops in 3D.

  18. 3D change detection at street level using mobile laser scanning point clouds and terrestrial images

    Science.gov (United States)

    Qin, Rongjun; Gruen, Armin

    2014-04-01

    Automatic change detection and geo-database updating in the urban environment are difficult tasks. There has been much research on detecting changes with satellite and aerial images, but studies have rarely been performed at the street level, which is complex in its 3D geometry. Contemporary geo-databases include 3D street-level objects, which demand frequent data updating. Terrestrial images provides rich texture information for change detection, but the change detection with terrestrial images from different epochs sometimes faces problems with illumination changes, perspective distortions and unreliable 3D geometry caused by the lack of performance of automatic image matchers, while mobile laser scanning (MLS) data acquired from different epochs provides accurate 3D geometry for change detection, but is very expensive for periodical acquisition. This paper proposes a new method for change detection at street level by using combination of MLS point clouds and terrestrial images: the accurate but expensive MLS data acquired from an early epoch serves as the reference, and terrestrial images or photogrammetric images captured from an image-based mobile mapping system (MMS) at a later epoch are used to detect the geometrical changes between different epochs. The method will automatically mark the possible changes in each view, which provides a cost-efficient method for frequent data updating. The methodology is divided into several steps. In the first step, the point clouds are recorded by the MLS system and processed, with data cleaned and classified by semi-automatic means. In the second step, terrestrial images or mobile mapping images at a later epoch are taken and registered to the point cloud, and then point clouds are projected on each image by a weighted window based z-buffering method for view dependent 2D triangulation. In the next step, stereo pairs of the terrestrial images are rectified and re-projected between each other to check the geometrical

  19. A miniaturised image based fluorescence detection system for point-of-care-testing of cocaine abuse

    Science.gov (United States)

    Walczak, Rafał; Krüger, Jan; Moynihan, Shane

    2015-08-01

    In this paper, we describe a miniaturised image-based fluorescence detection system and demonstrate its viability as a highly sensitive tool for point-of-care-analysis of drugs of abuse in human sweat with a focus on monitor individuals for drugs of abuse. Investigations of miniaturised and low power optoelectronic configurations and methodologies for real-time image analysis were successfully carried out. The miniaturised fluorescence detection system was validated against a reference detection system under controlled laboratory conditions by analysing spiked sweat samples in dip stick and then strip with sample pad. As a result of the validation studies, a 1 ng mL-1 limit of detection of cocaine in sweat and full agreement of test results with the reference detection system can be reported. Results of the investigations open the way towards a detection system that integrates a hand-held fluorescence reader and a wearable skinpatch, and which can collect and in situ analyse sweat for the presence of cocaine at any point for up to tenths hours.

  20. Application of SQUID to magnetic contaminant detection

    International Nuclear Information System (INIS)

    We have developed a magnetic metallic contaminant detector using a high-temperature superconducting quantum interference device (HTS-SQUID) gradiometer for industrial products such as lithium ion batteries. Finding ultrasmall metallic contaminants is a critical issue for manufacturers producing commercial products such as lithium ion batteries. When contamination occurs, the manufacturer incurs a great loss in recalling the tainted products. We employed a permanent ring magnet for magnetizing the products in order to generate remnant fields only at the ends of the products, thereby reducing their impact in masking the field from a contaminant. For practical applications, the detection width of a sensor must be sufficiently large to identify an inclusion from above the product during inspection. Here, we made a large SQUID gradiometer 8 mm in width and compared its detection width with that of a conventional small sensor 3 mm wide. We found that the effective detection width of the 8 mm sensor was 11.6 mm. It was 1.8 times larger than that of the small sensor. Finally, a test of the system's performance revealed that iron particles as small as 50 μm x 50 μm on the electrode of a lithium ion battery could be detected clearly.

  1. Multispectral IR detection modules and applications

    Science.gov (United States)

    Münzberg, M.; Breiter, R.; Cabanski, W.; Lutz, H.; Wendler, J.; Ziegler, J.; Rehm, R.; Walther, M.

    2006-05-01

    This paper is intended to present firstly the current status at AIM on quantum well (QWIP) and antimonide superlattices (SL) detection modules for multi spectral ground and airborne applications in the high performance range i.e. for missile approach warning systems and secondly presents possibilities with long linear arrays i.e. 576x7 MCT to measure spectral selective in the 2 - 11μm wavelength range. QWIP and antimonide based superlattice (SL) modules are developed and produced in a work share between AIM and the Fraunhofer Institute for Applied Solid State Physics (IAF). The sensitive layers are manufactured by the IAF, hybridized and integrated to IDCA or camera level by AIM. In case of MCT based modules, all steps are done by AIM. QWIP dual band or dual color detectors provide good resolution as long as integration times in the order of 5-10ms can be tolerated. This is acceptable for all applications where no fast motions of the platform or the targets are to be expected. For spectral selective detection, a QWIP detector combining 3-5 μm (MWIR) and 8-10 μm (LWIR) detection in each pixel with coincident integration has been developed in a 384x288x2 format with 40 μm pitch. Excellent thermal resolution with NETD crosstalk in the array usually observed in QWIP arrays resulting in low MTF values was suppressed resulting in sharp image impression. For rapidly changing scenes - like e.g. in case of missile warning applications for airborne platforms - a material system with higher quantum efficiency is required to limit integration times to typically 1ms. AIM and IAF selected antimonide based type II superlattices (SL) for such kind of applications. The type II SL technology provides - similar to QWIPs - an accurate engineering of sensitive layers by MBE with very good homogeneity and potentially good yield and resistivity against high temperature application i.e. under processing or storage. While promising results on single SL pixels have been reported since

  2. Comparison of point counts and territory mapping for detecting effects of forest management on songbirds

    Science.gov (United States)

    Newell, Felicity L.; Sheehan, James; Wood, Petra Bohall; Rodewald, Amanda D.; Buehler, David A.; Keyser, Patrick D.; Larkin, Jeffrey L.; Beachy, Tiffany A.; Bakermans, Marja H.; Boves, Than J.; Evans, Andrea; George, Gregory A.; McDermott, Molly E.; Perkins, Kelly A.; White, Matthew; Wigley, T. Bently

    2013-01-01

    Point counts are commonly used to assess changes in bird abundance, including analytical approaches such as distance sampling that estimate density. Point-count methods have come under increasing scrutiny because effects of detection probability and field error are difficult to quantify. For seven forest songbirds, we compared fixed-radii counts (50 m and 100 m) and density estimates obtained from distance sampling to known numbers of birds determined by territory mapping. We applied point-count analytic approaches to a typical forest management question and compared results to those obtained by territory mapping. We used a before–after control impact (BACI) analysis with a data set collected across seven study areas in the central Appalachians from 2006 to 2010. Using a 50-m fixed radius, variance in error was at least 1.5 times that of the other methods, whereas a 100-m fixed radius underestimated actual density by >3 territories per 10 ha for the most abundant species. Distance sampling improved accuracy and precision compared to fixed-radius counts, although estimates were affected by birds counted outside 10-ha units. In the BACI analysis, territory mapping detected an overall treatment effect for five of the seven species, and effects were generally consistent each year. In contrast, all point-count methods failed to detect two treatment effects due to variance and error in annual estimates. Overall, our results highlight the need for adequate sample sizes to reduce variance, and skilled observers to reduce the level of error in point-count data. Ultimately, the advantages and disadvantages of different survey methods should be considered in the context of overall study design and objectives, allowing for trade-offs among effort, accuracy, and power to detect treatment effects.

  3. Detection of point sources on two-dimensional images based on peaks

    CERN Document Server

    Lopez-Caniego, M; Sanz, J L; Barreiro, R B

    2005-01-01

    This article considers the detection of point sources in two dimensional astronomical images. The detection scheme we propose is based on peak statistics. We discuss the example of the detection of far galaxies in Cosmic Microwave Background experiments throughout the paper, although the method we present is totally general and can be used in many other fields of data analysis. We assume sources with a Gaussian profile --that is a fair approximation of the profile of a point source convolved with the detector beam in microwave experiments-- on a background modeled by a homogeneous and isotropic Gaussian random field characterized by a scale-free power spectrum. Point sources are enhanced with respect to the background by means of linear filters. After filtering, we identify local maxima and apply our detection scheme, a Neyman-Pearson detector that defines our region of acceptance based on the a priori pdf of the sources and the ratio of number densities. We study the different performances of some linear fil...

  4. Application of Gist SVM in Cancer Detection

    CERN Document Server

    Aruna, S; Nandakishore, L V

    2012-01-01

    In this paper, we study the application of GIST SVM in disease prediction (detection of cancer). Pattern classification problems can be effectively solved by Support vector machines. Here we propose a classifier which can differentiate patients having benign and malignant cancer cells. To improve the accuracy of classification, we propose to determine the optimal size of the training set and perform feature selection. To find the optimal size of the training set, different sizes of training sets are experimented and the one with highest classification rate is selected. The optimal features are selected through their F-Scores.

  5. A proximal point algorithm for sequential feature extraction applications

    OpenAIRE

    Doan, Xuan Vinh; Toh, Kim-Chuan; Vavasis, Stephen

    2011-01-01

    We propose a proximal point algorithm to solve LAROS problem, that is the problem of finding a "large approximately rank-one submatrix". This LAROS problem is used to sequentially extract features in data. We also develop a new stopping criterion for the proximal point algorithm, which is based on the duality conditions of \\eps-optimal solutions of the LAROS problem, with a theoretical guarantee. We test our algorithm with two image databases and show that we can use the LAROS problem to extr...

  6. Radiation Detection for Homeland Security Applications

    Science.gov (United States)

    Ely, James

    2008-05-01

    In the past twenty years or so, there have been significant changes in the strategy and applications for homeland security. Recently there have been significant at deterring and interdicting terrorists and associated organizations. This is a shift in the normal paradigm of deterrence and surveillance of a nation and the `conventional' methods of warfare to the `unconventional' means that terrorist organizations resort to. With that shift comes the responsibility to monitor international borders for weapons of mass destruction, including radiological weapons. As a result, countries around the world are deploying radiation detection instrumentation to interdict the illegal shipment of radioactive material crossing international borders. These efforts include deployments at land, rail, air, and sea ports of entry in the US and in European and Asian countries. Radioactive signatures of concern include radiation dispersal devices (RDD), nuclear warheads, and special nuclear material (SNM). Radiation portal monitors (RPMs) are used as the main screening tool for vehicles and cargo at borders, supplemented by handheld detectors, personal radiation detectors, and x-ray imaging systems. This talk will present an overview of radiation detection equipment with emphasis on radiation portal monitors. In the US, the deployment of radiation detection equipment is being coordinated by the Domestic Nuclear Detection Office within the Department of Homeland Security, and a brief summary of the program will be covered. Challenges with current generation systems will be discussed as well as areas of investigation and opportunities for improvements. The next generation of radiation portal monitors is being produced under the Advanced Spectroscopic Portal program and will be available for deployment in the near future. Additional technologies, from commercially available to experimental, that provide additional information for radiation screening, such as density imaging equipment, will

  7. CVD diamond for nuclear detection applications

    International Nuclear Information System (INIS)

    Chemically vapour deposited (CVD) diamond is a remarkable material for the fabrication of radiation detectors. In fact, there exist several applications where other standard semiconductor detectors do not fulfil the specific requirements imposed by corrosive, hot and/or high radiation dose environments. The improvement of the electronic properties of CVD diamond has been under intensive investigations and led to the development of a few applications that are addressing specific industrial needs. Here, we report on CVD diamond-based detector developments and we describe how this material, even though of a polycrystalline nature, is readily of great interest for applications in the nuclear industry as well as for physics experiments. Improvements in the material synthesis as well as on device fabrication especially concern the synthesis of films that do not exhibit space charge build up effects which are often encountered in CVD diamond materials and that are highly detrimental for detection devices. On a pre-industrial basis, CVD diamond detectors have been fabricated for nuclear industry applications in hostile environments. Such devices can operate in harsh environments and overcome limitations encountered with the standard semiconductor materials. Of these, this paper presents devices for the monitoring of the alpha activity in corrosive nuclear waste solutions, such as those encountered in nuclear fuel assembly reprocessing facilities, as well as diamond-based thermal neutron detectors exhibiting a high neutron to gamma selectivity. All these demonstrate the effectiveness of a demanding industrial need that relies on the remarkable resilience of CVD diamond

  8. CVD diamond for nuclear detection applications

    Energy Technology Data Exchange (ETDEWEB)

    Bergonzo, P. E-mail: pbergonzo@cea.fr; Brambilla, A.; Tromson, D.; Mer, C.; Guizard, B.; Marshall, R.D.; Foulon, F

    2002-01-11

    Chemically vapour deposited (CVD) diamond is a remarkable material for the fabrication of radiation detectors. In fact, there exist several applications where other standard semiconductor detectors do not fulfil the specific requirements imposed by corrosive, hot and/or high radiation dose environments. The improvement of the electronic properties of CVD diamond has been under intensive investigations and led to the development of a few applications that are addressing specific industrial needs. Here, we report on CVD diamond-based detector developments and we describe how this material, even though of a polycrystalline nature, is readily of great interest for applications in the nuclear industry as well as for physics experiments. Improvements in the material synthesis as well as on device fabrication especially concern the synthesis of films that do not exhibit space charge build up effects which are often encountered in CVD diamond materials and that are highly detrimental for detection devices. On a pre-industrial basis, CVD diamond detectors have been fabricated for nuclear industry applications in hostile environments. Such devices can operate in harsh environments and overcome limitations encountered with the standard semiconductor materials. Of these, this paper presents devices for the monitoring of the alpha activity in corrosive nuclear waste solutions, such as those encountered in nuclear fuel assembly reprocessing facilities, as well as diamond-based thermal neutron detectors exhibiting a high neutron to gamma selectivity. All these demonstrate the effectiveness of a demanding industrial need that relies on the remarkable resilience of CVD diamond.

  9. Spatio-temporal point process filtering methods with an application

    Czech Academy of Sciences Publication Activity Database

    Frcalová, B.; Beneš, V.; Klement, Daniel

    2010-01-01

    Roč. 21, 3-4 (2010), s. 240-252. ISSN 1180-4009 R&D Projects: GA AV ČR(CZ) IAA101120604 Institutional research plan: CEZ:AV0Z50110509 Keywords : cox point process * filtering * spatio-temporal modelling * spike Subject RIV: BA - General Mathematics Impact factor: 0.750, year: 2010

  10. Unevenness Point Descriptor for Terrain Analysis in Mobile Robot Applications

    Directory of Open Access Journals (Sweden)

    Mauro Bellone

    2013-07-01

    The proposed algorithm is based on the analysis of the normal vector of a surface obtained through Principal Component Analysis and it leads to the definition of a novel, so defined, Unevenness Point Descriptor. Experimental results, obtained with vehicles operating in indoor and outdoor environments, are presented to validate this approach.

  11. Object Class Detection and Classification using Multi Scale Gradient and Corner Point based Shape Descriptors

    OpenAIRE

    Fernando, Basura; Karaoglu, Sezer; Saha, Sajib Kumar

    2015-01-01

    This paper presents a novel multi scale gradient and a corner point based shape descriptors. The novel multi scale gradient based shape descriptor is combined with generic Fourier descriptors to extract contour and region based shape information. Shape information based object class detection and classification technique with a random forest classifier has been optimized. Proposed integrated descriptor in this paper is robust to rotation, scale, translation, affine deformations, noisy contour...

  12. Detection of HIV cDNA Point Mutations with Rolling-Circle Amplification Arrays

    OpenAIRE

    Zhongwei Wu; Zuhong Lu; Quanjun Liu; Lingwei Wu

    2010-01-01

    In this paper we describe an isothermal rolling-circle amplification (RCA) protocol to detect gene point mutations on chips. The method is based on an allele-specific oligonucleotide circularization mediated by a special DNA ligase. The probe is circularized when perfect complementary sequences between the probe oligonucleotide and HIV cDNA gene. Mismatches around the ligation site can prevent probe circularization. The circularized probe (C-probe) can be amplified by rolling circle amplifica...

  13. 3D Sensor-Based Obstacle Detection Comparing Octrees and Point clouds Using CUDA

    OpenAIRE

    K.B. Kaldestad; G. Hovland; D.A. Anisi

    2012-01-01

    This paper presents adaptable methods for achieving fast collision detection using the GPU and Nvidia CUDA together with Octrees. Earlier related work have focused on serial methods, while this paper presents a parallel solution which shows that there is a great increase in time if the number of operations is large. Two different models of the environment and the industrial robot are presented, the first is Octrees at different resolutions, the second is a point cloud representation. The rela...

  14. Automatic Detection and Classi cation of Objects in Point Clouds using multi-stage Semantics

    OpenAIRE

    Truong, Hung; Hmida, Helmi Ben; Boochs, Frank; Habed, Adlane; Cruz, Christophe; Voisin, Yvon; Nicolle, Christophe

    2013-01-01

    International audience Due to the increasing availability of large unstructured point clouds from lasers scanning and photogrammetry, there is a growing demand for automatic evaluation methods. Given the complexity of the underlying problems, several new methods resort to using semantic knowledge in particular for object detection and classification support. In this paper, we present a novel approach, which makes use of advanced algorithms, and benefits from intelligent knowledge managemen...

  15. Incorporating Change-Point Detection Updates of Frequency-Magnitude Distributions Within the Taiwan Earthquake Catalog

    OpenAIRE

    Kuei-Pao Chen; Yi-Ben Tsai; Daniel Amorese; and Wen-Yen Chang

    2011-01-01

    Threshold magnitude (M0) is an important factor in determining the magnitude of completeness in calculating seismic b values. Seismic b values can assist in determining the likelihood of earthquake events; therefore, seismic b values should be re-determined repeatedly with ever increasing precision. In this study, we use a median-based analysis of the segment slope (MBASS) to detect change points in Gutenberg-Richter frequency-magnitude distributions (FMDs) to determine M0. Results give the b...

  16. Resolution of point sources of light as analyzed by quantum detection theory.

    Science.gov (United States)

    Helstrom, C. W.

    1973-01-01

    The resolvability of point sources of incoherent thermal light is analyzed by quantum detection theory in terms of two hypothesis-testing problems. In the first, the observer must decide whether there are two sources of equal radiant power at given locations, or whether there is only one source of twice the power located midway between them. In the second problem, either one, but not both, of two point sources is radiating, and the observer must decide which it is. The decisions are based on optimum processing of the electromagnetic field at the aperture of an optical instrument. In both problems the density operators of the field under the two hypotheses do not commute. The error probabilities, determined as functions of the separation of the points and the mean number of received photons, characterize the ultimate resolvability of the sources.

  17. The resolution of point sources of light as analyzed by quantum detection theory

    Science.gov (United States)

    Helstrom, C. W.

    1972-01-01

    The resolvability of point sources of incoherent light is analyzed by quantum detection theory in terms of two hypothesis-testing problems. In the first, the observer must decide whether there are two sources of equal radiant power at given locations, or whether there is only one source of twice the power located midway between them. In the second problem, either one, but not both, of two point sources is radiating, and the observer must decide which it is. The decisions are based on optimum processing of the electromagnetic field at the aperture of an optical instrument. In both problems the density operators of the field under the two hypotheses do not commute. The error probabilities, determined as functions of the separation of the points and the mean number of received photons, characterize the ultimate resolvability of the sources.

  18. Point processes with contagion and an application to credit risk

    OpenAIRE

    Dassios, Angelos; Zhao, Hongbiao

    2010-01-01

    We introduce a new point process, the dynamic contagion process, by generalising the self excited Hawkes process (with exponential decay) by Hawkes (1971) and the Cox process with shot noise intensity by Dassios and Jang (2003). Our process includes both self excited and externally excited jumps, which can be used to model the dynamic contagion impact from endogenous and exogenous factors of the underlying system. We have systematically analysed the theoretical properties of...

  19. Poisson point processes and their application to Markov processes

    CERN Document Server

    Itô, Kiyosi

    2015-01-01

    An extension problem (often called a boundary problem) of Markov processes has been studied, particularly in the case of one-dimensional diffusion processes, by W. Feller, K. Itô, and H. P. McKean, among others. In this book, Itô discussed a case of a general Markov process with state space S and a specified point a ∈ S called a boundary. The problem is to obtain all possible recurrent extensions of a given minimal process (i.e., the process on S \\ {a} which is absorbed on reaching the boundary a). The study in this lecture is restricted to a simpler case of the boundary a being a discontinuous entrance point, leaving a more general case of a continuous entrance point to future works. He established a one-to-one correspondence between a recurrent extension and a pair of a positive measure k(db) on S \\ {a} (called the jumping-in measure and a non-negative number m< (called the stagnancy rate). The necessary and sufficient conditions for a pair k, m was obtained so that the correspondence is precisely de...

  20. Contrast Invariant Interest Point Detection by Zero-Norm LoG Filter.

    Science.gov (United States)

    Zhenwei Miao; Xudong Jiang; Kim-Hui Yap

    2016-01-01

    The Laplacian of Gaussian (LoG) filter is widely used in interest point detection. However, low-contrast image structures, though stable and significant, are often submerged by the high-contrast ones in the response image of the LoG filter, and hence are difficult to be detected. To solve this problem, we derive a generalized LoG filter, and propose a zero-norm LoG filter. The response of the zero-norm LoG filter is proportional to the weighted number of bright/dark pixels in a local region, which makes this filter be invariant to the image contrast. Based on the zero-norm LoG filter, we develop an interest point detector to extract local structures from images. Compared with the contrast dependent detectors, such as the popular scale invariant feature transform detector, the proposed detector is robust to illumination changes and abrupt variations of images. Experiments on benchmark databases demonstrate the superior performance of the proposed zero-norm LoG detector in terms of the repeatability and matching score of the detected points as well as the image recognition rate under different conditions. PMID:26302514

  1. Detection of fault structures with airborne LiDAR point-cloud data

    Science.gov (United States)

    Chen, Jie; Du, Lei

    2015-08-01

    The airborne LiDAR (Light Detection And Ranging) technology is a new type of aerial earth observation method which can be used to produce high-precision DEM (Digital Elevation Model) quickly and reflect ground surface information directly. Fault structure is one of the key forms of crustal movement, and its quantitative description is the key to the research of crustal movement. The airborne LiDAR point-cloud data is used to detect and extract fault structures automatically based on linear extension, elevation mutation and slope abnormal characteristics. Firstly, the LiDAR point-cloud data is processed to filter out buildings, vegetation and other non-surface information with the TIN (Triangulated Irregular Network) filtering method and Burman model calibration method. TIN and DEM are made from the processed data sequentially. Secondly, linear fault structures are extracted based on dual-threshold method. Finally, high-precision DOM (Digital Orthophoto Map) and other geological knowledge are used to check the accuracy of fault structure extraction. An experiment is carried out in Beiya Village of Yunnan Province, China. With LiDAR technology, results reveal that: the airborne LiDAR point-cloud data can be utilized to extract linear fault structures accurately and automatically, measure information such as height, width and slope of fault structures with high precision, and detect faults in areas with vegetation coverage effectively.

  2. Fast and Robust Segmentation and Classification for Change Detection in Urban Point Clouds

    Science.gov (United States)

    Roynard, X.; Deschaud, J.-E.; Goulette, F.

    2016-06-01

    Change detection is an important issue in city monitoring to analyse street furniture, road works, car parking, etc. For example, parking surveys are needed but are currently a laborious task involving sending operators in the streets to identify the changes in car locations. In this paper, we propose a method that performs a fast and robust segmentation and classification of urban point clouds, that can be used for change detection. We apply this method to detect the cars, as a particular object class, in order to perform parking surveys automatically. A recently proposed method already addresses the need for fast segmentation and classification of urban point clouds, using elevation images. The interest to work on images is that processing is much faster, proven and robust. However there may be a loss of information in complex 3D cases: for example when objects are one above the other, typically a car under a tree or a pedestrian under a balcony. In this paper we propose a method that retain the three-dimensional information while preserving fast computation times and improving segmentation and classification accuracy. It is based on fast region-growing using an octree, for the segmentation, and specific descriptors with Random-Forest for the classification. Experiments have been performed on large urban point clouds acquired by Mobile Laser Scanning. They show that the method is as fast as the state of the art, and that it gives more robust results in the complex 3D cases.

  3. Comparative classification analysis of post-harvest growth detection from terrestrial LiDAR point clouds in precision agriculture

    Science.gov (United States)

    Koenig, Kristina; Höfle, Bernhard; Hämmerle, Martin; Jarmer, Thomas; Siegmann, Bastian; Lilienthal, Holger

    2015-06-01

    In precision agriculture, detailed geoinformation on plant and soil properties plays an important role, e.g., in crop protection or the application of fertilizers. This paper presents a comparative classification analysis for post-harvest growth detection using geometric and radiometric point cloud features of terrestrial laser scanning (TLS) data, considering the local neighborhood of each point. Radiometric correction of the TLS data was performed via an empirical range-correction function derived from a field experiment. Thereafter, the corrected amplitude and local elevation features were explored regarding their importance for classification. For the comparison, tree induction, Naive Bayes, and k-Means-derived classifiers were tested for different point densities to distinguish between ground and post-harvest growth. The classification performance was validated against highly detailed RGB reference images and the red edge normalized difference vegetation index (NDVI705), derived from a hyperspectral sensor. Using both geometric and radiometric features, we achieved a precision of 99% with the tree induction. Compared to the reference image classification, the calculated post-harvest growth coverage map reached an accuracy of 80%. RGB and LiDAR-derived coverage showed a polynomial correlation to NDVI705 of degree two with R2 of 0.8 and 0.7, respectively. Larger post-harvest growth patches (>10 × 10 cm) could already be detected by a point density of 2 pts./0.01 m2. The results indicate a high potential of radiometric and geometric LiDAR point cloud features for the identification of post-harvest growth using tree induction classification. The proposed technique can potentially be applied over larger areas using vehicle-mounted scanners.

  4. Scale-space point spread function based framework to boost infrared target detection algorithms

    Science.gov (United States)

    Moradi, Saed; Moallem, Payman; Sabahi, Mohamad Farzan

    2016-07-01

    Small target detection is one of the major concern in the development of infrared surveillance systems. Detection algorithms based on Gaussian target modeling have attracted most attention from researchers in this field. However, the lack of accurate target modeling limits the performance of this type of infrared small target detection algorithms. In this paper, signal to clutter ratio (SCR) improvement mechanism based on the matched filter is described in detail and effect of Point Spread Function (PSF) on the intensity and spatial distribution of the target pixels is clarified comprehensively. In the following, a new parametric model for small infrared targets is developed based on the PSF of imaging system which can be considered as a matched filter. Based on this model, a new framework to boost model-based infrared target detection algorithms is presented. In order to show the performance of this new framework, the proposed model is adopted in Laplacian scale-space algorithms which is a well-known algorithm in the small infrared target detection field. Simulation results show that the proposed framework has better detection performance in comparison with the Gaussian one and improves the overall performance of IRST system. By analyzing the performance of the proposed algorithm based on this new framework in a quantitative manner, this new framework shows at least 20% improvement in the output SCR values in comparison with Laplacian of Gaussian (LoG) algorithm.

  5. A remote technologies application program at Nine Mile Point

    International Nuclear Information System (INIS)

    Traditionally, the use of robotics and remote technologies within the nuclear industry has been limited to hot cell facilities for fuel processing and highly radioactive sample handling. However, now faced with increasing pressures to reduce occupational radiation exposures as low as reasonable achievable (ALARA), the nuclear utility industry is looking beyond the traditional exposure reduction methods and is slowly and carefully entering into robotic automation. The purpose of this presentation is to describe the efforts, achievements, and experiences of the personnel at the Niagara Mohawk Power Corporation (NMPC) Nine Miles Point Nuclear Stations to become involved in this emerging technology

  6. Multiple Monte Carlo Testing with Applications in Spatial Point Processes

    DEFF Research Database (Denmark)

    Mrkvička, Tomáš; Myllymäki, Mari; Hahn, Ute

    function(s) lead to the rejection at the prescribed significance level of the test. Examples of null hypothesis from point process and random set statistics are used to demonstrate the strength of the rank envelope test. The examples include goodness-of-fit test with several test functions, goodness...... with a function as the test statistic, 3) several Monte Carlo tests with functions as test statistics. The rank test has correct (global) type I error in each case and it is accompanied with a p-value and with a graphical interpretation which shows which subtest or which distances of the used test...

  7. Fixed point results for generalized alpha-psi-contractions in metric-like spaces and applications

    Directory of Open Access Journals (Sweden)

    Hassen Aydi

    2015-05-01

    Full Text Available In this article, we introduce the concept of generalized $\\alpha\\text{-}\\psi$-contraction in the context of metric-like spaces and establish some related fixed point theorems. As consequences, we obtain some known fixed point results in the literature. Some examples and an application on two-point boundary value problems for second order differential equation are also considered.

  8. Dynamic social community detection and its applications.

    Directory of Open Access Journals (Sweden)

    Nam P Nguyen

    Full Text Available Community structure is one of the most commonly observed features of Online Social Networks (OSNs in reality. The knowledge of this feature is of great advantage: it not only provides helpful insights into developing more efficient social-aware solutions but also promises a wide range of applications enabled by social and mobile networking, such as routing strategies in Mobile Ad Hoc Networks (MANETs and worm containment in OSNs. Unfortunately, understanding this structure is very challenging, especially in dynamic social networks where social interactions are evolving rapidly. Our work focuses on the following questions: How can we efficiently identify communities in dynamic social networks? How can we adaptively update the network community structure based on its history instead of recomputing from scratch? To this end, we present Quick Community Adaptation (QCA, an adaptive modularity-based framework for not only discovering but also tracing the evolution of network communities in dynamic OSNs. QCA is very fast and efficient in the sense that it adaptively updates and discovers the new community structure based on its history together with the network changes only. This flexible approach makes QCA an ideal framework applicable for analyzing large-scale dynamic social networks due to its lightweight computing-resource requirement. To illustrate the effectiveness of our framework, we extensively test QCA on both synthesized and real-world social networks including Enron, arXiv e-print citation, and Facebook networks. Finally, we demonstrate the applicability of QCA in real applications: (1 A social-aware message forwarding strategy in MANETs, and (2 worm propagation containment in OSNs. Competitive results in comparison with other methods reveal that social-based techniques employing QCA as a community detection core outperform current available methods.

  9. Dynamic social community detection and its applications.

    Science.gov (United States)

    Nguyen, Nam P; Dinh, Thang N; Shen, Yilin; Thai, My T

    2014-01-01

    Community structure is one of the most commonly observed features of Online Social Networks (OSNs) in reality. The knowledge of this feature is of great advantage: it not only provides helpful insights into developing more efficient social-aware solutions but also promises a wide range of applications enabled by social and mobile networking, such as routing strategies in Mobile Ad Hoc Networks (MANETs) and worm containment in OSNs. Unfortunately, understanding this structure is very challenging, especially in dynamic social networks where social interactions are evolving rapidly. Our work focuses on the following questions: How can we efficiently identify communities in dynamic social networks? How can we adaptively update the network community structure based on its history instead of recomputing from scratch? To this end, we present Quick Community Adaptation (QCA), an adaptive modularity-based framework for not only discovering but also tracing the evolution of network communities in dynamic OSNs. QCA is very fast and efficient in the sense that it adaptively updates and discovers the new community structure based on its history together with the network changes only. This flexible approach makes QCA an ideal framework applicable for analyzing large-scale dynamic social networks due to its lightweight computing-resource requirement. To illustrate the effectiveness of our framework, we extensively test QCA on both synthesized and real-world social networks including Enron, arXiv e-print citation, and Facebook networks. Finally, we demonstrate the applicability of QCA in real applications: (1) A social-aware message forwarding strategy in MANETs, and (2) worm propagation containment in OSNs. Competitive results in comparison with other methods reveal that social-based techniques employing QCA as a community detection core outperform current available methods. PMID:24722164

  10. High sensitive detection of presenilin-1 point mutation based on electrochemiluminescence

    Institute of Scientific and Technical Information of China (English)

    ZHU Debin; XING Da; SHEN Xingyan; YAN Guihong

    2003-01-01

    Electrochemiluminescence (ECL) is a high- sensitive detection method with broad biological applications. Ruthenium (Ⅱ) tris (bipyridyl) and tripropylamine (TPA) are most commomly used combination of the reactive species in ECL. The redox of with excess TPA at the surface of an electrode produces a highly efficient and stable light emission due to a rapid cycle of the reactions. This rapid, highly sensitive and accurate method has been applied to gene quantification. In this work, an ECL detection system is designed and applied in detection of presenilin-1 (PS-1) gene mutation. The results show that given the same polymerase chain reaction (PCR) cycle number, the ECL intensities from the digested and the undigested wild-type samples are nearly identical, but the difference in ECL intensities between the digested and the undigested mutant samples is distinctive. This detection technology connects PCR with ECL and allows a reliable discrimination between the wild-type and the mutant genes.

  11. A positive fixed point theorem with applications to systems of Hammerstein integral equations

    OpenAIRE

    Cabada, Alberto; Cid, José Ángel; Infante, Gennaro

    2014-01-01

    We present new criteria on the existence of fixed points that combine some monotonicity assumptions with the classical fixed point index theory. As an illustrative application, we use our theoretical results to prove the existence of positive solutions for systems of nonlinear Hammerstein integral equations. An example is also presented to show the applicability of our results.

  12. LC vision application to malignant tumor detection

    Science.gov (United States)

    Tomilin, Maxim G.; Kurmashev, A. F.; Povzun, Sergey A.

    2004-05-01

    The free thin nematic liquid crystal (NLC) layers applied on the surface and observed in polarizing microscope are being used in the science and high technologies for structural inhomogeneities detection on the surface of materials. Simplicity, efficiency and high sensitivity have given an opportunity of NLC application in cancer detection. There were three stages in our investigations. 1. It was discovered that on malignant tissues of animals and human beings NLC have homeotropic orientation while on benign tissues they have planar or tilted orientation. 2. The discovered phenomenon was explained by the surface tension value difference on malignant and benign tumors. 3. The difference in surface tension is based on the particularities of the different parts of the interface layer. The "water" on the boundary with malignant tissues has higher order parameter in comparison with benign tissue. The difference in order parameter was explained by higher concentration of the protein and less concentration of lipids in the "water" on malignant tissues. As the result the anchoring NLC energy on the surface of structural water is higher in comparison with benign tissue. In the first case the NLC have homeotropic orientation in the whole volume of NLC layer while in the second case the surface Fredericks transition is observed.

  13. Singing voice detection for karaoke application

    Science.gov (United States)

    Shenoy, Arun; Wu, Yuansheng; Wang, Ye

    2005-07-01

    We present a framework to detect the regions of singing voice in musical audio signals. This work is oriented towards the development of a robust transcriber of lyrics for karaoke applications. The technique leverages on a combination of low-level audio features and higher level musical knowledge of rhythm and tonality. Musical knowledge of the key is used to create a song-specific filterbank to attenuate the presence of the pitched musical instruments. This is followed by subband processing of the audio to detect the musical octaves in which the vocals are present. Text processing is employed to approximate the duration of the sung passages using freely available lyrics. This is used to obtain a dynamic threshold for vocal/ non-vocal segmentation. This pairing of audio and text processing helps create a more accurate system. Experimental evaluation on a small database of popular songs shows the validity of the proposed approach. Holistic and per-component evaluation of the system is conducted and various improvements are discussed.

  14. PRA [probabilistic risk assessment] application to Point Beach

    International Nuclear Information System (INIS)

    The results of a best-estimate probabilistic risk assessment (PRA) of the fire contribution to Decay Heat Removal (DHR) risk at the Point Beach nuclear power plant are presented. This analysis yields an approximately two-order-of-magnitude lower contribution to core damage frequency (CDF) than indicated by an earlier study conducted by Sandia National Laboratories (SNL). The principal reasons for the differing CDF estimates are explored by means of a comparative evaluation of the two studies. Chief among these differences is the estimate of Halon fire suppression reliability. The scaling approaches used to apportion generic fire frequency data to individual fire zones within the plant also contribute notably. The results of this analysis suggest that traditional fire analysis methods systematically overstate the risk due to fires at all nuclear power plants. 13 refs

  15. Application of Relevance Vector Machines in Real Time Intrusion Detection

    Directory of Open Access Journals (Sweden)

    Naveen N. C

    2012-09-01

    Full Text Available In the recent years, there has been a growing interest in the development of change detection techniques for the analysis of Intrusion Detection. This interest stems from the wide range of applications in which change detection methods can be used. Detecting the changes by observing data collected at different times is one of the most important applications of network security because they can provide analysis of short interval on global scale. Research in exploring change detection techniques for medium/high network data can be found for the new generation of very high resolution data. The advent of these technologies has greatly increased the ability to monitor and resolve the details of changes and makes it possible to analyze. At the same time, they present a new challenge over other technologies in that a relatively large amount of data must be analyzed and corrected for registration and classification errors to identify frequently changing trend. In this research paper an approach for Intrusion Detection System (IDS which embeds a Change Detection Algorithm with Relevance Vector Machine (RVM is proposed. IDS are considered as a complex task that handles a huge amount of network related data with different parameters. Current research work has proved that kernel learning based methods are very effective in addressing these problems. In contrast to Support Vector Machines (SVM, the RVM provides a probabilistic output while preserving the accuracy. The focus of this paper is to model RVM that can work with large network data set in a real environment and develop RVM classifier for IDS. The new model consists of Change Point (CP and RVM which is competitive in processing time and improve the classification performance compared to other known classification model like SVM. The goal is to make the system simple but efficient in detecting network intrusion in an actual real time environment. Results show that the model learns more effectively

  16. Application of detecting algorithm based on network

    Institute of Scientific and Technical Information of China (English)

    张凤斌; 杨永田; 江子扬; 孙冰心

    2004-01-01

    Because currently intrusion detection systems cannot detect undefined intrusion behavior effectively,according to the robustness and adaptability of the genetic algorithms, this paper integrates the genetic algorithms into an intrusion detection system, and a detection algorithm based on network traffic is proposed. This algorithm is a real-time and self-study algorithm and can detect undefined intrusion behaviors effectively.

  17. A mobile-health application to detect wandering patterns of elderly people in home environment.

    Science.gov (United States)

    Vuong, N K; Goh, S G A; Chan, S; Lau, C T

    2013-01-01

    Wandering is a common and risky behavior in people with dementia (PWD). In this paper, we present a mobile healthcare application to detect wandering patterns in indoor settings. The application harnesses consumer electronics devices including WiFi access points and mobile phones and has been tested successfully in a home environment. Experimental results show that the mobile-health application is able to detect wandering patterns including lapping, pacing and random in real-time. Once wandering is detected, an alert message is sent using SMS (Short Message Service) to attending caregivers or physicians for further examination and timely interventions. PMID:24111292

  18. Label-free detection of DNA hybridization and single point mutations in a nano-gap biosensor

    Science.gov (United States)

    Zaffino, R. L.; Mir, M.; Samitier, J.

    2014-03-01

    We describe a conductance-based biosensor that exploits DNA-mediated long-range electron transport for the label-free and direct electrical detection of DNA hybridization. This biosensor platform comprises an array of vertical nano-gap biosensors made of gold and fabricated through standard photolithography combined with focused ion beam lithography. The nano-gap walls are covalently modified with short, anti-symmetric thiolated DNA probes, which are terminated by 19 bases complementary to both the ends of a target DNA strand. The nano-gaps are separated by a distance of 50nm, which was adjusted to fit the length of the DNA target plus the DNA probes. The hybridization of the target DNA closes the gap circuit in a switch on/off fashion, in such a way that it is readily detected by an increase in the current after nano-gap closure. The nano-biosensor shows high specificity in the discrimination of base-pair mismatching and does not require signal indicators or enhancing molecules. The design of the biosensor platform is applicable for multiplexed detection in a straightforward manner. The platform is well-suited to mass production, point-of-care diagnostics, and wide-scale DNA analysis applications.

  19. Label-free detection of DNA hybridization and single point mutations in a nano-gap biosensor

    International Nuclear Information System (INIS)

    We describe a conductance-based biosensor that exploits DNA-mediated long-range electron transport for the label-free and direct electrical detection of DNA hybridization. This biosensor platform comprises an array of vertical nano-gap biosensors made of gold and fabricated through standard photolithography combined with focused ion beam lithography. The nano-gap walls are covalently modified with short, anti-symmetric thiolated DNA probes, which are terminated by 19 bases complementary to both the ends of a target DNA strand. The nano-gaps are separated by a distance of 50nm, which was adjusted to fit the length of the DNA target plus the DNA probes. The hybridization of the target DNA closes the gap circuit in a switch on/off fashion, in such a way that it is readily detected by an increase in the current after nano-gap closure. The nano-biosensor shows high specificity in the discrimination of base-pair mismatching and does not require signal indicators or enhancing molecules. The design of the biosensor platform is applicable for multiplexed detection in a straightforward manner. The platform is well-suited to mass production, point-of-care diagnostics, and wide-scale DNA analysis applications. (paper)

  20. Applications of pattern recognition techniques to online fault detection

    International Nuclear Information System (INIS)

    A common problem to operators of complex industrial systems is the early detection of incipient degradation of sensors and components in order to avoid unplanned outages, to orderly plan for anticipated maintenance activities and to assure continued safe operation. In such systems, there usually are a large number of sensors (upwards of several thousand is not uncommon) serving many functions, ranging from input to control systems, monitoring of safety parameters and component performance limits, system environmental conditions, etc. Although sensors deemed to measure important process conditions are generally alarmed, the alarm set points usually are just high-low limits and the operator's response to such alarms is based on written procedures and his or her experience and training. In many systems this approach has been successful, but in situations where the cost of a forced outage is high an improved method is needed. In such cases it is desirable, if not necessary, to detect disturbances in either sensors or the process prior to any actual failure that could either shut down the process or challenge any safety system that is present. Recent advances in various artificial intelligence techniques have provided the opportunity to perform such functions of early detection and diagnosis. In this paper, the experience gained through the application of several pattern-recognition techniques to the on-line monitoring and incipient disturbance detection of several coolant pumps and numerous sensors at the Experimental Breeder Reactor-II (EBR-II) which is located at the Idaho National Engineering Laboratory is presented

  1. Learning search-driven application development with SharePoint 2013

    CERN Document Server

    Tordgeman, Johnny

    2013-01-01

    A fast paced, practical guide, filled with code examples and demonstrations of enterprise search using SharePoint 2013.This book is written for SharePoint and JavaScript developers who want to get started with SharePoint search and create search-driven applications. The book assumes working knowledge with previous versions of SharePoint and some experience with JavaScript and client side development

  2. Point mutation in a family with hyperproinsulinemia detected by single stranded conformational polymorphism

    Energy Technology Data Exchange (ETDEWEB)

    Nakashima, Naoki; Sakamoto, Norihiro; Umeda, Fumio; Hashimoto, Toshihiko; Hisatomi, Akitaka; Umemura, Tsukuru; Sakaki, Yoshiyuki; Nawata, Hajime (Kyushu Univ., Fukuoka (Japan)); Aso, Nobunori (Kaho Hospital, Fukuoka (Japan))

    1993-03-01

    The authors previously described a case of familial hyperproinsulinemia, the fifth to be reported. In the present study they characterized the genetic defect carried by this family and demonstrated that it could be detected by polymerase chain reaction-single stranded conformational polymorphism. Since the serum proinsulin molecule from the propositus, a 63-yr-old Japanese man, was eluted on the same fraction of human proinsulin intermediate cleaved only at the B-C junction, the authors sequenced exon 3 of his insulin gene, including the C-A junction. A point mutation was discovered that changed codon 65 from arginine (CGT) to histidine (CAT) in one allele. This was the same point mutation as that described previously in three unrelated kindreds representing two races, consistent with the hypothesis that the dinucleotide sequence CpG may be a hot spot for mutations. Recently, developed polymerase chain reaction-single stranded conformational polymorphism proved useful in detecting this mutation in the family members. The daughter of the propositus and one of his two grandsons were also demonstrated to be heterozygous for this point mutation by this method. 25 refs., 2 figs.

  3. Instrument-Free Point-of-Care Molecular Detection of Zika Virus

    Science.gov (United States)

    2016-01-01

    The recent outbreak of Zika virus (ZIKV) infection in the Americas and its devastating impact on fetal development have prompted the World Health Organization (WHO) to declare the ZIKV pandemic as a Public Health Emergency of International Concern. Rapid and reliable diagnostics for ZIKV are vital because ZIKV-infected individuals display no symptoms or nonspecific symptoms similar to other viral infections. Because immunoassays lack adequate sensitivity and selectivity and are unable to identify active state of infection, molecular diagnostics are an effective means to detect ZIKV soon after infection and throughout pregnancy. We report on a highly sensitive reverse-transcription loop-mediated, isothermal amplification (RT-LAMP) assay for rapid detection of ZIKV and its implementation in a simple, easy-to-use, inexpensive, point-of-care (POC) disposable cassette that carries out all the unit operations from sample introduction to detection. For thermal control of the cassette, we use a chemically heated cup without a need for electrical power. Amplification products are detected with leuco crystal violet (LCV) dye by eye without a need for instrumentation. We demonstrated the utility of our POC diagnostic system by detecting ZIKV in oral samples with sensitivity of 5 plaque-forming units (PFU) in less than 40 min. Our system is particularly suitable for resource-poor settings, where centralized laboratory facilities, funds, and trained personnel are in short supply, and for use in doctors’ offices, clinics, and at home. PMID:27306491

  4. Instrument-Free Point-of-Care Molecular Detection of Zika Virus.

    Science.gov (United States)

    Song, Jinzhao; Mauk, Michael G; Hackett, Brent A; Cherry, Sara; Bau, Haim H; Liu, Changchun

    2016-07-19

    The recent outbreak of Zika virus (ZIKV) infection in the Americas and its devastating impact on fetal development have prompted the World Health Organization (WHO) to declare the ZIKV pandemic as a Public Health Emergency of International Concern. Rapid and reliable diagnostics for ZIKV are vital because ZIKV-infected individuals display no symptoms or nonspecific symptoms similar to other viral infections. Because immunoassays lack adequate sensitivity and selectivity and are unable to identify active state of infection, molecular diagnostics are an effective means to detect ZIKV soon after infection and throughout pregnancy. We report on a highly sensitive reverse-transcription loop-mediated, isothermal amplification (RT-LAMP) assay for rapid detection of ZIKV and its implementation in a simple, easy-to-use, inexpensive, point-of-care (POC) disposable cassette that carries out all the unit operations from sample introduction to detection. For thermal control of the cassette, we use a chemically heated cup without a need for electrical power. Amplification products are detected with leuco crystal violet (LCV) dye by eye without a need for instrumentation. We demonstrated the utility of our POC diagnostic system by detecting ZIKV in oral samples with sensitivity of 5 plaque-forming units (PFU) in less than 40 min. Our system is particularly suitable for resource-poor settings, where centralized laboratory facilities, funds, and trained personnel are in short supply, and for use in doctors' offices, clinics, and at home. PMID:27306491

  5. The uniformly most powerful invariant test for two models of detection function in point transect sampling

    Directory of Open Access Journals (Sweden)

    Riccardo Borgoni

    2013-05-01

    Full Text Available Estimating population abundance is of primary interest in wildlife population studies. Point transect sampling is a well established methodology for this purpose. The usual approach for estimating the density or the size of the population of interest is to assume a particular model for the detection function (the conditional probability of detecting an animal given that it is at a certain distance from the observer. Two popular models for this function are the half-normal model and the negative exponential model. However, it appears that the estimates are extremely sensitive to the shape of the detection function, particularly to the so-called shoulder condition, which ensures that an animal is nearly certain to be detected if it is at a small distance from the observer. The half-normal model satisfies this condition whereas the negative exponential does not. Testing whether such a hypothesis is consistent with the data at hand should be a primary concern. Given that the problem of testing the shoulder condition of a detection function is invariant under the group of scale transformations, in this paper we propose the uniformly most powerful.

  6. Detection of HIV cDNA Point Mutations with Rolling-Circle Amplification Arrays

    Directory of Open Access Journals (Sweden)

    Zhongwei Wu

    2010-01-01

    Full Text Available In this paper we describe an isothermal rolling-circle amplification (RCA protocol to detect gene point mutations on chips. The method is based on an allele-specific oligonucleotide circularization mediated by a special DNA ligase. The probe is circularized when perfect complementary sequences between the probe oligonucleotide and HIV cDNA gene. Mismatches around the ligation site can prevent probe circularization. The circularized probe (C-probe can be amplified by rolling circle amplification to generate multimeric singlestranded DNA (ssDNA under isothermal conditions. There are four sequence regions to bind respectively with fluorescent probe, RCA primer, solid probe and HIV cDNA template in the C-probe which we designed. These ssDNA products are hybridized with fluorescent probes and solid probes which are immobilized on a glass slide composing a regular microarray pattern. The fluorescence signals can be monitored by a scanner in the presence of HIV cDNA templates, whereas the probes cannot be circularized and signal of fluorescence cannot be found. The RCA array has capability of high-throughput detection of the point mutation and the single-nucleotide polymorphism (SNP.The development of C-probe-based technologies offers a promising prospect for situ detection, microarray, molecular diagnosis, single nucleotide polymorphism, and whole genome amplification.

  7. An Instantaneous Low-Cost Point-of-Care Anemia Detection Device

    Directory of Open Access Journals (Sweden)

    Jaime Punter-Villagrasa

    2015-02-01

    Full Text Available We present a small, compact and portable device for point-of-care instantaneous early detection of anemia. The method used is based on direct hematocrit measurement from whole blood samples by means of impedance analysis. This device consists of a custom electronic instrumentation and a plug-and-play disposable sensor. The designed electronics rely on straightforward standards for low power consumption, resulting in a robust and low consumption device making it completely mobile with a long battery life. Another approach could be powering the system based on other solutions like indoor solar cells, or applying energy-harvesting solutions in order to remove the batteries. The sensing system is based on a disposable low-cost label-free three gold electrode commercial sensor for 50 µL blood samples. The device capability for anemia detection has been validated through 24 blood samples, obtained from four hospitalized patients at Hospital Clínic. As a result, the response, effectiveness and robustness of the portable point-of-care device to detect anemia has been proved with an accuracy error of 2.83% and a mean coefficient of variation of 2.57% without any particular case above 5%.

  8. Candida vaccines development from point view of US patent application.

    Science.gov (United States)

    Wang, Shyh-Jen

    2011-11-01

    Candidiasis is the fourth most common bloodstream infection in hospitalized patients in the United States. Moreover, the mortality rate from Candida infections remains high, even after treatment with antifungal therapy. Vaccination would be a promising strategy for prevention of invasive fungal infections. In order to examine the main trends in anticandidal vaccine patenting activity, we conducted an analysis for anticandidal vaccine patents. We find 190 issued patent and 940 patent application documents containing the keywords Candida and vaccine within claims in the USA. Candida vaccines development, as evidenced by the numbers of issued patents, has decreased since the year 2002. Furthermore, the number of patent applications in Candida vaccines may indicate the strength of engaged resources were also in the status of stagnation during 2005-2007 and even a decline in 2008. Academic and nonprofit research institutions not only account for a large share of Candida vaccines patents but also apply for patents continually. Based on this analysis, the strength of Candida vaccines resources seems to remain stagnant in recent years due to patent prosecution or technical barrier in the filed of Candida vaccines. Therefore, we consider that Candida vaccines technology to still be under development and the researchers are still looking for scientific breakthrough in the filed. PMID:22048114

  9. The Development of an UAV Borne Direct Georeferenced Photogrammetric Platform for Ground Control Point Free Applications

    Directory of Open Access Journals (Sweden)

    Chien-Hsun Chu

    2012-07-01

    Full Text Available To facilitate applications such as environment detection or disaster monitoring, the development of rapid low cost systems for collecting near real time spatial information is very critical. Rapid spatial information collection has become an emerging trend for remote sensing and mapping applications. In this study, a fixed-wing Unmanned Aerial Vehicle (UAV-based spatial information acquisition platform that can operate in Ground Control Point (GCP free environments is developed and evaluated. The proposed UAV based photogrammetric platform has a Direct Georeferencing (DG module that includes a low cost Micro Electro Mechanical Systems (MEMS Inertial Navigation System (INS/ Global Positioning System (GPS integrated system. The DG module is able to provide GPS single frequency carrier phase measurements for differential processing to obtain sufficient positioning accuracy. All necessary calibration procedures are implemented. Ultimately, a flight test is performed to verify the positioning accuracy in DG mode without using GCPs. The preliminary results of positioning accuracy in DG mode illustrate that horizontal positioning accuracies in the x and y axes are around 5 m at 300 m flight height above the ground. The positioning accuracy of the z axis is below 10 m. Therefore, the proposed platform is relatively safe and inexpensive for collecting critical spatial information for urgent response such as disaster relief and assessment applications where GCPs are not available.

  10. People Detection Based on Spatial Mapping of Friendliness and Floor Boundary Points for a Mobile Navigation Robot

    Directory of Open Access Journals (Sweden)

    Tsuyoshi Tasaki

    2011-01-01

    Full Text Available Navigation robots must single out partners requiring navigation and move in the cluttered environment where people walk around. Developing such robots requires two different people detections: detecting partners and detecting all moving people around the robots. For detecting partners, we design divided spaces based on the spatial relationships and sensing ranges. Mapping the friendliness of each divided space based on the stimulus from the multiple sensors to detect people calling robots positively, robots detect partners on the highest friendliness space. For detecting moving people, we regard objects’ floor boundary points in an omnidirectional image as obstacles. We classify obstacles as moving people by comparing movement of each point with robot movement using odometry data, dynamically changing thresholds to detect. Our robot detected 95.0% of partners while it stands by and interacts with people and detected 85.0% of moving people while robot moves, which was four times higher than previous methods did.

  11. Intersection Detection Based on Qualitative Spatial Reasoning on Stopping Point Clusters

    Science.gov (United States)

    Zourlidou, S.; Sester, M.

    2016-06-01

    The purpose of this research is to propose and test a method for detecting intersections by analysing collectively acquired trajectories of moving vehicles. Instead of solely relying on the geometric features of the trajectories, such as heading changes, which may indicate turning points and consequently intersections, we extract semantic features of the trajectories in form of sequences of stops and moves. Under this spatiotemporal prism, the extracted semantic information which indicates where vehicles stop can reveal important locations, such as junctions. The advantage of the proposed approach in comparison with existing turning-points oriented approaches is that it can detect intersections even when not all the crossing road segments are sampled and therefore no turning points are observed in the trajectories. The challenge with this approach is that first of all, not all vehicles stop at the same location - thus, the stop-location is blurred along the direction of the road; this, secondly, leads to the effect that nearby junctions can induce similar stop-locations. As a first step, a density-based clustering is applied on the layer of stop observations and clusters of stop events are found. Representative points of the clusters are determined (one per cluster) and in a last step the existence of an intersection is clarified based on spatial relational cluster reasoning, with which less informative geospatial clusters, in terms of whether a junction exists and where its centre lies, are transformed in more informative ones. Relational reasoning criteria, based on the relative orientation of the clusters with their adjacent ones are discussed for making sense of the relation that connects them, and finally for forming groups of stop events that belong to the same junction.

  12. Spine Localization in X-ray Images Using Interest Point Detection

    OpenAIRE

    Benjelloun, Mohammed; Mahmoudi, Saïd

    2008-01-01

    This study was conducted to evaluate a new method used to calculate vertebra orientation in medical x-ray images. The goal of this work is to develop an x-ray image segmentation approach used to identify the location and the orientation of the cervical vertebrae in medical images. We propose a method for localization of vertebrae by extracting the anterior—left—faces of vertebra contours. This approach is based on automatic corner points of interest detection. For this task, we use the Harris...

  13. Potentiometric end point detection in the EDTA titrimetric determination of gallium

    International Nuclear Information System (INIS)

    Gallium is titrated in presence of known amount of Fe (III) with EDTA in HNO3 solution at pH 2 to 3. The end point is detected potentiometrically employing a bright platinum wire - saturated calomel (SCE) reference electrode system, the redox couple being Fe (III) / Fe (II). Since Fe (III) is also titrated by EDTA, it is, therefore, subtracted from titre value to get the EDTA equivalent to gallium only. Precision and accuracy 0.2 to 0.4% was obtained in the results of gallium in the range of 8 to 2 mg. (author)

  14. SMC-PHD based multi-target track-before-detect with nonstandard point observations model

    Institute of Scientific and Technical Information of China (English)

    占荣辉; 高彦钊; 胡杰民; 张军

    2015-01-01

    Detection and tracking of multi-target with unknown and varying number is a challenging issue, especially under the condition of low signal-to-noise ratio (SNR). A modified multi-target track-before-detect (TBD) method was proposed to tackle this issue using a nonstandard point observation model. The method was developed from sequential Monte Carlo (SMC)-based probability hypothesis density (PHD) filter, and it was implemented by modifying the original calculation in update weights of the particles and by adopting an adaptive particle sampling strategy. To efficiently execute the SMC-PHD based TBD method, a fast implementation approach was also presented by partitioning the particles into multiple subsets according to their position coordinates in 2D resolution cells of the sensor. Simulation results show the effectiveness of the proposed method for time-varying multi-target tracking using raw observation data.

  15. A catalog of 203 galaxy clusters serendipitously detected in the ROSAT PSPC pointed observations

    DEFF Research Database (Denmark)

    Vikhlinin, A.; McNamara, B.R.; Forman, W.;

    1998-01-01

    ), corresponding to very poor groups, to similar to 5 x 10(44) ergs s(-1), corresponding to rich clusters. The cluster redshifts range from z = 0.015 to z > 0.5. The catalog lists X-ray fluxes, core radii, and spectroscopic redshifts for 73 clusters and photometric redshifts for the remainder. Our detection method......We present a catalog of 203 clusters of galaxies serendipitously detected in 647 ROSAT PSPC high Galactic latitude pointings covering 158 deg(2). This is one of the largest X-ray-selected cluster samples, comparable in size only to the ROSAT All-Sky Survey sample of nearby clusters (Ebeling et al....... 1997). We detect clusters in the inner 17.'5 of the ROSAT PSPC field of view using the spatial extent of their X-ray emission. Fluxes of detected clusters range from 1.6 x 10(-14) to 8 x 10(-12) ergs s(-1) cm(-2) in the 0.5-2 keV energy band. X-ray luminosities range from 10(42) ergs s(-1...

  16. An integrated lateral flow assay for effective DNA amplification and detection at the point of care.

    Science.gov (United States)

    Choi, Jane Ru; Hu, Jie; Gong, Yan; Feng, Shangsheng; Wan Abas, Wan Abu Bakar; Pingguan-Murphy, Belinda; Xu, Feng

    2016-05-10

    Lateral flow assays (LFAs) have been extensively explored in nucleic acid testing (NAT) for medical diagnostics, food safety analysis and environmental monitoring. However, the amount of target nucleic acid in a raw sample is usually too low to be directly detected by LFAs, necessitating the process of amplification. Even though cost-effective paper-based amplification techniques have been introduced, they have always been separately performed from LFAs, hence increasing the risk of reagent loss and cross-contaminations. To date, integrating paper-based nucleic acid amplification into colorimetric LFA in a simple, portable and cost-effective manner has not been introduced. Herein, we developed an integrated LFA with the aid of a specially designed handheld battery-powered system for effective amplification and detection of targets in resource-poor settings. Interestingly, using the integrated paper-based loop-mediated isothermal amplification (LAMP)-LFA, we successfully performed highly sensitive and specific target detection, achieving a detection limit of as low as 3 × 10(3) copies of target DNA, which is comparable to the conventional tube-based LAMP-LFA in an unintegrated format. The device may serve in conjunction with a simple paper-based sample preparation to create a fully integrated paper-based sample-to-answer diagnostic device for point-of-care testing (POCT) in the near future. PMID:27010033

  17. Towards detection and diagnosis of Ebola virus disease at point-of-care.

    Science.gov (United States)

    Kaushik, Ajeet; Tiwari, Sneham; Dev Jayant, Rahul; Marty, Aileen; Nair, Madhavan

    2016-01-15

    Ebola outbreak-2014 (mainly Zaire strain related Ebola virus) has been declared most widely spread deadly persistent epidemic due to unavailability of rapid diagnostic, detection, and therapeutics. Ebola virus disease (EVD), a severe viral hemorrhagic fever syndrome caused by Ebola virus (EBOV) is transmitted by direct contact with the body fluids of infected person and objects contaminated with virus or infected animals. World Health Organization (WHO) has declared EVD epidemic as public health emergency of international concern with severe global economic burden. At fatal EBOV infection stage, patients usually die before the antibody response. Currently, rapid blood tests to diagnose EBOV infection include the antigen or antibodies capture using ELISA and RNA detection using RT/Q-PCR within 3-10 days after the onset of symptoms. Moreover, few nanotechnology-based colorimetric and paper-based immunoassay methods have been recently reported to detect Ebola virus. Unfortunately, these methods are limited to laboratory only. As state-of-the art (SoA) diagnostics time to confirm Ebola infection, varies from 6h to about 3 days, it causes delay in therapeutic approaches. Thus developing a cost-effective, rapid, sensitive, and selective sensor to detect EVD at point-of-care (POC) is certainly worth exploring to establish rapid diagnostics to decide therapeutics. This review highlights SoA of Ebola diagnostics and also a call to develop rapid, selective and sensitive POC detection of EBOV for global health care. We propose that adopting miniaturized electrochemical EBOV immunosensing can detect virus level at pM concentration within ∼40min compared to 3 days of ELISA test at nM levels. PMID:26319169

  18. Estimating the effects of detection heterogeneity and overdispersion on trends estimated from avian point counts.

    Science.gov (United States)

    Etterson, Matthew A; Niemi, Gerald J; Danz, Nicholas P

    2009-12-01

    Point counts are a common method for sampling avian distribution and abundance. Although methods for estimating detection probabilities are available, many analyses use raw counts and do not correct for detectability. We use a removal model of detection within an N-mixture approach to estimate abundance trends corrected for imperfect detection. We compare the corrected trend estimates to those estimated from raw counts for 16 species using 15 years of monitoring data on three national forests in the western Great Lakes, USA. We also tested the effects of overdispersion by modeling both counts and removal mixtures under three statistical distributions: Poisson, zero-inflated Poisson, and negative binomial. For most species, the removal model produced estimates of detection probability that conformed to expectations. For many species, but not all, estimates of trends were similar regardless of statistical distribution or method of analysis. Within a given combination of likelihood (counts vs. mixtures) and statistical distribution, trends usually differed by both stand type and national forest, with species showing declines in some stand types and increases in others. For three species, Brown Creeper, Yellow-rumped Warbler, and Black-throated Green Warbler, temporal patterns in detectability resulted in substantial differences in estimated trends under the removal mixtures compared to the analysis of raw counts. Overall, we found that the zero-inflated Poisson was the best distribution for our data, although the Poisson or negative binomial performed better for a few species. The similarity in estimated trends that we observed among counts and removal mixtures was probably a result of both experimental design and sampling effort. First, the study was originally designed to avoid confounding observer effects with habitats or time. Second, our time series is relatively long and our sample sizes within years are large. PMID:20014578

  19. A rich Internet application for automated detection of road blockage in post-disaster scenarios

    International Nuclear Information System (INIS)

    This paper presents the development of a rich Internet application for automated detection of road blockage in post-disaster scenarios using volunteered geographic information from OpenStreetMap street centerlines and airborne light detection and ranging (LiDAR) data. The architecture of the application on the client-side and server-side was described. The major functionality of the application includes shapefile uploading, Web editing for spatial features, road blockage detection, and blockage points downloading. An example from the 2010 Haiti earthquake was included to demonstrate the effectiveness of the application. The results suggest that the prototype application can effectively detect (1) road blockage caused by earthquakes, and (2) some human errors caused by contributors of volunteered geographic information

  20. A rich Internet application for automated detection of road blockage in post-disaster scenarios

    Science.gov (United States)

    Liu, W.; Dong, P.; Liu, S.; Liu, J.

    2014-02-01

    This paper presents the development of a rich Internet application for automated detection of road blockage in post-disaster scenarios using volunteered geographic information from OpenStreetMap street centerlines and airborne light detection and ranging (LiDAR) data. The architecture of the application on the client-side and server-side was described. The major functionality of the application includes shapefile uploading, Web editing for spatial features, road blockage detection, and blockage points downloading. An example from the 2010 Haiti earthquake was included to demonstrate the effectiveness of the application. The results suggest that the prototype application can effectively detect (1) road blockage caused by earthquakes, and (2) some human errors caused by contributors of volunteered geographic information.

  1. Synthesis and applications of magnetic nanoparticles for biorecognition and point of care medical diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Sandhu, Adarsh [Electronics-Inspired Interdisciplinary Research Institute (EIIRIS), Toyohashi University of Technology, 1-1 Hibarigaoka, Tempaku, Toyohashi 441-8580 (Japan); Handa, Hiroshi [Integrated Research Institute, Tokyo Institute of Technology, Yokohama 226-8503 (Japan); Abe, Masanori [Department of Electrical and Electronic Engineering, Tokyo Institute of Technology, 2-12-1 O-okayama, Meguro-ku, Tokyo 152-8552 (Japan)

    2010-11-05

    sized 'probe beads' by nanometer sized 'target beads', enabling the detection of small concentrations of beads as small as 8 nm in 'pumpless' microcapillary systems. Finally, we describe a 'label-less homogeneous' procedure referred to as 'magneto-optical transmission (MT) sensing', where the optical transmission of a solution containing rotating linear chains of magnetic nanobeads was used to detect biomolecules with pM-level sensitivity with a dynamic range of more than four orders of magnitude. Our research on the synthesis and applications of nanoparticles is particularly suitable for point of care diagnostics. (topical review)

  2. Synthesis and applications of magnetic nanoparticles for biorecognition and point of care medical diagnostics

    International Nuclear Information System (INIS)

    ' by nanometer sized 'target beads', enabling the detection of small concentrations of beads as small as 8 nm in 'pumpless' microcapillary systems. Finally, we describe a 'label-less homogeneous' procedure referred to as 'magneto-optical transmission (MT) sensing', where the optical transmission of a solution containing rotating linear chains of magnetic nanobeads was used to detect biomolecules with pM-level sensitivity with a dynamic range of more than four orders of magnitude. Our research on the synthesis and applications of nanoparticles is particularly suitable for point of care diagnostics. (topical review)

  3. The Italian Lightning Detection System of CESI and its applications

    International Nuclear Information System (INIS)

    Aim of the paper is to give a description of the CESI lightning detection system SIRF. The system allows the real time localization (latitude, longitude) of the striking point of a cloud-to-ground lightning flash. Electrical parameters of the impulsive currents related to the flash strokes are calculated as well. Based on sensors covering the whole Italian territory, SIRF configuration and of the basic calculation criteria for passing from the sensor raw data to the final flash data is given together with the evaluation of the system expected performance parameters (accuracy, detection efficiently, signal/noise ratio). Main uses of lightning data in several fields are then reported, with special reference to electrical applications. Mention is done about the different modalities adopted for data distribution, according to that either real time or passed time applications have to be carried out. In this latter case (e.g. statistics), a huge amount of data archived within the Lightning Data Base of SIRF is available

  4. Using opcode-sequences to detect malicious Android applications

    OpenAIRE

    Jerome, Quentin; Allix, Kevin; State, Radu; Engel, Thomas

    2014-01-01

    Recently, the Android platform has seen its number of malicious applications increased sharply. Motivated by the easy application submission process and the number of alternative market places for distributing Android applications, rogue authors are developing constantly new malicious programs. While current anti-virus software mainly relies on signature detection, the issue of alternative malware detection has to be addressed. In this paper, we present a feature based detection mechanism rel...

  5. ROM Plus®: accurate point-of-care detection of ruptured fetal membranes

    Directory of Open Access Journals (Sweden)

    McQuivey RW

    2016-05-01

    Full Text Available Ross W McQuivey,1 Jon E Block2 1Clinical Affairs, Clinical Innovations, Salt Lake City, UT, 2Independent Clinical Consultant, San Francisco, CA, USAAbstract: Accurate and timely diagnosis of rupture of fetal membranes is imperative to inform and guide gestational age-specific interventions to optimize perinatal outcomes and reduce the risk of serious complications, including preterm delivery and infections. The ROM Plus is a rapid, point-of-care, qualitative immunochromatographic diagnostic test that uses a unique monoclonal/polyclonal antibody approach to detect two different proteins found in amniotic fluid at high concentrations: alpha-fetoprotein and insulin-like growth factor binding protein-1. Clinical study results have uniformly demonstrated high diagnostic accuracy and performance characteristics with this point-of-care test that exceeds conventional clinical testing with external laboratory evaluation. The description, indications for use, procedural steps, and laboratory and clinical characterization of this assay are presented in this article.Keywords: ROM Plus®, premature rupture of membranes, point-of-care immunoassay, insulin-like growth factor binding protein-1, IGFBP-1, placental protein 12, PP12, alpha-fetoprotein, AFP

  6. Evolvable Smartphone-Based Platforms for Point-of-Care In-Vitro Diagnostics Applications

    Directory of Open Access Journals (Sweden)

    François Patou

    2016-09-01

    Full Text Available The association of smart mobile devices and lab-on-chip technologies offers unprecedented opportunities for the emergence of direct-to-consumer in vitro medical diagnostics applications. Despite their clear transformative potential, obstacles remain to the large-scale disruption and long-lasting success of these systems in the consumer market. For instance, the increasing level of complexity of instrumented lab-on-chip devices, coupled to the sporadic nature of point-of-care testing, threatens the viability of a business model mainly relying on disposable/consumable lab-on-chips. We argued recently that system evolvability, defined as the design characteristic that facilitates more manageable transitions between system generations via the modification of an inherited design, can help remedy these limitations. In this paper, we discuss how platform-based design can constitute a formal entry point to the design and implementation of evolvable smart device/lab-on-chip systems. We present both a hardware/software design framework and the implementation details of a platform prototype enabling at this stage the interfacing of several lab-on-chip variants relying on current- or impedance-based biosensors. Our findings suggest that several change-enabling mechanisms implemented in the higher abstraction software layers of the system can promote evolvability, together with the design of change-absorbing hardware/software interfaces. Our platform architecture is based on a mobile software application programming interface coupled to a modular hardware accessory. It allows the specification of lab-on-chip operation and post-analytic functions at the mobile software layer. We demonstrate its potential by operating a simple lab-on-chip to carry out the detection of dopamine using various electroanalytical methods.

  7. Evolvable Smartphone-Based Platforms for Point-of-Care In-Vitro Diagnostics Applications.

    Science.gov (United States)

    Patou, François; AlZahra'a Alatraktchi, Fatima; Kjægaard, Claus; Dimaki, Maria; Madsen, Jan; Svendsen, Winnie E

    2016-01-01

    The association of smart mobile devices and lab-on-chip technologies offers unprecedented opportunities for the emergence of direct-to-consumer in vitro medical diagnostics applications. Despite their clear transformative potential, obstacles remain to the large-scale disruption and long-lasting success of these systems in the consumer market. For instance, the increasing level of complexity of instrumented lab-on-chip devices, coupled to the sporadic nature of point-of-care testing, threatens the viability of a business model mainly relying on disposable/consumable lab-on-chips. We argued recently that system evolvability, defined as the design characteristic that facilitates more manageable transitions between system generations via the modification of an inherited design, can help remedy these limitations. In this paper, we discuss how platform-based design can constitute a formal entry point to the design and implementation of evolvable smart device/lab-on-chip systems. We present both a hardware/software design framework and the implementation details of a platform prototype enabling at this stage the interfacing of several lab-on-chip variants relying on current- or impedance-based biosensors. Our findings suggest that several change-enabling mechanisms implemented in the higher abstraction software layers of the system can promote evolvability, together with the design of change-absorbing hardware/software interfaces. Our platform architecture is based on a mobile software application programming interface coupled to a modular hardware accessory. It allows the specification of lab-on-chip operation and post-analytic functions at the mobile software layer. We demonstrate its potential by operating a simple lab-on-chip to carry out the detection of dopamine using various electroanalytical methods. PMID:27598208

  8. Geodetic Control Points, Wisconsin HARN, Published in 1993, Not Applicable scale, Dunn County, WI.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Geodetic Control Points dataset, published at Not Applicable scale, was produced all or in part from Field Survey/GPS information as of 1993. It is described...

  9. A catalog of 203 galaxy clusters serendipitously detected in the ROSAT PSPC pointed observations

    DEFF Research Database (Denmark)

    Vikhlinin, A.; McNamara, B.R.; Forman, W.; Jones, C.; Quintana, H.; Hornstrup, Allan

    1998-01-01

    We present a catalog of 203 clusters of galaxies serendipitously detected in 647 ROSAT PSPC high Galactic latitude pointings covering 158 deg(2). This is one of the largest X-ray-selected cluster samples, comparable in size only to the ROSAT All-Sky Survey sample of nearby clusters (Ebeling et al....... 1997). We detect clusters in the inner 17.'5 of the ROSAT PSPC field of view using the spatial extent of their X-ray emission. Fluxes of detected clusters range from 1.6 x 10(-14) to 8 x 10(-12) ergs s(-1) cm(-2) in the 0.5-2 keV energy band. X-ray luminosities range from 10(42) ergs s(-1......, optimized for finding extended sources in the presence of source confusion, is described in detail. Selection effects necessary for a statistical analysis of the cluster sample are comprehensively studied by Monte Carlo simulations. We have optically confirmed 203 of 223 X-ray sources as clusters of...

  10. [Detection of the point of communication by pneumoperitoneum at the surgery for pleuroperitoneal communication].

    Science.gov (United States)

    Okubo, T; Takahashi, H; Kaneko, Y; Kurokawa, T; Yokoyama, K; Motohara, T

    2010-05-01

    A 53-year-old male was admitted to our hospital because of dyspnea. Chest radiograph showed a massive right-sided hydrothorax. He was suffering from chronic renal failure and had undergone continuous ambulatory peritoneal dialysis (CAPD) for 8 months. The diagnosis of pleuroperitoneal communication (PPC) was made using injection of indigocarmine into the peritoneal cavity with subsequent pleural detection by thoracocentesis. Injection of contrast media into the peritoneal cavity showed a dome shaped radio-opaque shadow which is located on the diaphragmatic dome followed by the movement of contrast media into the thoracic cavity. Video-assisted thoracic surgery (VATS) was performed under general anesthesia. To identify the point of communication, the method of detecting air leakage was employed. A bleb like lesion on which the hole existed was observed at the center of the diaphragm, and air leakage was identified by filling the thoracic cavity with saline. The pressure in the peritoneal cavity was maintained at 10 mmHg by continuous CO2 inflation. Direct closure was performed to repair the PPC, which succesfully stopped the air leakage. CAPD could be restarted immediately after surgery. No recurrence of hydrothorax has been detected for more than 14 months after surgery. PMID:20446603

  11. Detection of Deviations in Mobile Applications Network Behavior

    OpenAIRE

    Chekina, L.; Mimran, D.; Rokach, L.; Elovici, Y.; Shapira, B.

    2012-01-01

    In this paper a novel system for detecting meaningful deviations in a mobile application's network behavior is proposed. The main goal of the proposed system is to protect mobile device users and cellular infrastructure companies from malicious applications. The new system is capable of: (1) identifying malicious attacks or masquerading applications installed on a mobile device, and (2) identifying republishing of popular applications injected with a malicious code. The detection is performed...

  12. a Robust Registration Algorithm for Point Clouds from Uav Images for Change Detection

    Science.gov (United States)

    Al-Rawabdeh, A.; Al-Gurrani, H.; Al-Durgham, K.; Detchev, I.; He, F.; El-Sheimy, N.; Habib, A.

    2016-06-01

    Landslides are among the major threats to urban landscape and manmade infrastructure. They often cause economic losses, property damages, and loss of lives. Temporal monitoring data of landslides from different epochs empowers the evaluation of landslide progression. Alignment of overlapping surfaces from two or more epochs is crucial for the proper analysis of landslide dynamics. The traditional methods for point-cloud-based landslide monitoring rely on using a variation of the Iterative Closest Point (ICP) registration procedure to align any reconstructed surfaces from different epochs to a common reference frame. However, sometimes the ICP-based registration can fail or may not provide sufficient accuracy. For example, point clouds from different epochs might fit to local minima due to lack of geometrical variability within the data. Also, manual interaction is required to exclude any non-stable areas from the registration process. In this paper, a robust image-based registration method is introduced for the simultaneous evaluation of all registration parameters. This includes the Interior Orientation Parameters (IOPs) of the camera and the Exterior Orientation Parameters (EOPs) of the involved images from all available observation epochs via a bundle block adjustment with self-calibration. Next, a semi-global dense matching technique is implemented to generate dense 3D point clouds for each epoch using the images captured in a particular epoch separately. The normal distances between any two consecutive point clouds can then be readily computed, because the point clouds are already effectively co-registered. A low-cost DJI Phantom II Unmanned Aerial Vehicle (UAV) was customised and used in this research for temporal data collection over an active soil creep area in Lethbridge, Alberta, Canada. The customisation included adding a GPS logger and a Large-Field-Of-View (LFOV) action camera which facilitated capturing high-resolution geo-tagged images in two epochs

  13. Applications of fixed point theorems in the theory of invariant subspaces

    OpenAIRE

    Espínola García, Rafael; Lacruz Martín, Miguel Benito

    2012-01-01

    We survey several applications of fixed point theorems in the theory of invariant subspaces. The general idea is that a fixed point theorem applied to a suitable map yields the existence of invariant subspaces for an operator on a Banach space.

  14. Non-uniqueness of the point of application of the buoyancy force

    Energy Technology Data Exchange (ETDEWEB)

    Kliava, Janis; Megel, Jacques, E-mail: janis.kliava@u-bordeaux1.f [CPMOH UMR 5798 Universite de Bordeaux1-CNRS, 351 cours de la Liberation, 33405 Talence cedex (France)

    2010-07-15

    Even though the buoyancy force (also known as the Archimedes force) has always been an important topic of academic studies in physics, its point of application has not been explicitly identified yet. We present a quantitative approach to this problem based on the concept of the hydrostatic energy, considered here for a general shape of the cross-section of a floating body and for an arbitrary angle of heel. We show that the location of the point of application of the buoyancy force essentially depends (i) on the type of motion experienced by the floating body and (ii) on the definition of this point. In a rolling/pitching motion, considerations involving the rotational moment lead to a particular dynamical point of application of the buoyancy force, and for some simple shapes of the floating body this point coincides with the well-known metacentre. On the other hand, from the work-energy relation it follows that in the rolling/pitching motion the energetical point of application of this force is rigidly connected to the centre of buoyancy; in contrast, in a vertical translation this point is rigidly connected to the centre of gravity of the body. Finally, we consider the location of the characteristic points of the floating bodies for some particular shapes of immersed cross-sections. The paper is intended for higher education level physics teachers and students.

  15. Non-uniqueness of the point of application of the buoyancy force

    International Nuclear Information System (INIS)

    Even though the buoyancy force (also known as the Archimedes force) has always been an important topic of academic studies in physics, its point of application has not been explicitly identified yet. We present a quantitative approach to this problem based on the concept of the hydrostatic energy, considered here for a general shape of the cross-section of a floating body and for an arbitrary angle of heel. We show that the location of the point of application of the buoyancy force essentially depends (i) on the type of motion experienced by the floating body and (ii) on the definition of this point. In a rolling/pitching motion, considerations involving the rotational moment lead to a particular dynamical point of application of the buoyancy force, and for some simple shapes of the floating body this point coincides with the well-known metacentre. On the other hand, from the work-energy relation it follows that in the rolling/pitching motion the energetical point of application of this force is rigidly connected to the centre of buoyancy; in contrast, in a vertical translation this point is rigidly connected to the centre of gravity of the body. Finally, we consider the location of the characteristic points of the floating bodies for some particular shapes of immersed cross-sections. The paper is intended for higher education level physics teachers and students.

  16. 75 FR 33657 - Submission for Review: Application for 10-Point Veteran Preference, 3206-0001

    Science.gov (United States)

    2010-06-14

    ... MANAGEMENT Submission for Review: Application for 10-Point Veteran Preference, 3206-0001 AGENCY: U.S. Office... for 10-Point Veteran Preference. DATES: Comments are encouraged and will be accepted until August 13... Preference, is used by OPM examining offices and agency appointing officials to adjudicate...

  17. 75 FR 53001 - Submission for Review: Application for 10-Point Veteran Preference, 3206-0001

    Science.gov (United States)

    2010-08-30

    ... was previously published in the Federal Register on June 14, 2010, at 75 FR 33657 allowing for a 60... MANAGEMENT Submission for Review: Application for 10-Point Veteran Preference, 3206-0001 AGENCY: U.S. Office... for 10-Point Veterans' Preference. As required by the Paperwork Reduction Act of 1995 (Pub. L....

  18. A Canonical Ensemble Approach to the Fermion/Boson Random Point Processes and Its Applications

    Science.gov (United States)

    Tamura, H.; Ito, K. R.

    2006-04-01

    We introduce the boson and the fermion point processes from the elementary quantum mechanical point of view. That is, we consider quantum statistical mechanics of the canonical ensemble for a fixed number of particles which obey Bose-Einstein, Fermi-Dirac statistics, respectively, in a finite volume. Focusing on the distribution of positions of the particles, we have point processes of the fixed number of points in a bounded domain. By taking the thermodynamic limit such that the particle density converges to a finite value, the boson/fermion processes are obtained. This argument is a realization of the equivalence of ensembles, since resulting processes are considered to describe a grand canonical ensemble of points. Random point processes corresponding to para-particles of order two are discussed as an application of the formulation. Statistics of a system of composite particles at zero temperature are also considered as a model of determinantal random point processes.

  19. Theoretical demonstration of the hybrid focusing points of sonic crystal flat lenses and possible applications

    International Nuclear Information System (INIS)

    We demonstrate the hybrid focusing points of sonic crystals for a multi-source array applied to flat sonic crystal lenses. The contributions of different point source couples form hybrid focusing points. Ray-trace analyses are conducted for acoustic flat lenses with multi-source configurations. The finite-difference time-domain (FDTD) simulation of flat lenses with multi-source configurations demonstrates the establishment of pure and hybrid focusing points in a pyramidal constellation. The number of focusing points in the pyramidal constellation depends on the number of point sources. We propose an acoustic device for fine-tuning the location of a far-field hybrid focusing point and discuss its benefits for acoustic energy focusing application

  20. Context-aware event detection smartphone application for first responders

    Science.gov (United States)

    Boddhu, Sanjay K.; Dave, Rakesh P.; McCartney, Matt; West, James A.; Williams, Robert L.

    2013-05-01

    The rise of social networking platforms like Twitter, Facebook, etc…, have provided seamless sharing of information (as chat, video and other media) among its user community on a global scale. Further, the proliferation of the smartphones and their connectivity networks has powered the ordinary individuals to share and acquire information regarding the events happening in his/her immediate vicinity in a real-time fashion. This human-centric sensed data being generated in "human-as-sensor" approach is tremendously valuable as it delivered mostly with apt annotations and ground truth that would be missing in traditional machine-centric sensors, besides high redundancy factor (same data thru multiple users). Further, when appropriately employed this real-time data can support in detecting localized events like fire, accidents, shooting, etc…, as they unfold and pin-point individuals being affected by those events. This spatiotemporal information, when made available for first responders in the event vicinity (or approaching it) can greatly assist them to make effective decisions to protect property and life in a timely fashion. In this vein, under SATE and YATE programs, the research team at AFRL Tec^Edge Discovery labs had demonstrated the feasibility of developing Smartphone applications, that can provide a augmented reality view of the appropriate detected events in a given geographical location (localized) and also provide an event search capability over a large geographic extent. In its current state, the application thru its backend connectivity utilizes a data (Text & Image) processing framework, which deals with data challenges like; identifying and aggregating important events, analyzing and correlating the events temporally and spatially and building a search enabled event database. Further, the smartphone application with its backend data processing workflow has been successfully field tested with live user generated feeds.

  1. Automatic Detection and Classification of Pole-Like Objects in Urban Point Cloud Data Using an Anomaly Detection Algorithm

    Directory of Open Access Journals (Sweden)

    Borja Rodríguez-Cuenca

    2015-09-01

    Full Text Available Detecting and modeling urban furniture are of particular interest for urban management and the development of autonomous driving systems. This paper presents a novel method for detecting and classifying vertical urban objects and trees from unstructured three-dimensional mobile laser scanner (MLS or terrestrial laser scanner (TLS point cloud data. The method includes an automatic initial segmentation to remove the parts of the original cloud that are not of interest for detecting vertical objects, by means of a geometric index based on features of the point cloud. Vertical object detection is carried out through the Reed and Xiaoli (RX anomaly detection algorithm applied to a pillar structure in which the point cloud was previously organized. A clustering algorithm is then used to classify the detected vertical elements as man-made poles or trees. The effectiveness of the proposed method was tested in two point clouds from heterogeneous street scenarios and measured by two different sensors. The results for the two test sites achieved detection rates higher than 96%; the classification accuracy was around 95%, and the completion quality of both procedures was 90%. Non-detected poles come from occlusions in the point cloud and low-height traffic signs; most misclassifications occurred in man-made poles adjacent to trees.

  2. 3D Sensor-Based Obstacle Detection Comparing Octrees and Point clouds Using CUDA

    Directory of Open Access Journals (Sweden)

    K.B. Kaldestad

    2012-10-01

    Full Text Available This paper presents adaptable methods for achieving fast collision detection using the GPU and Nvidia CUDA together with Octrees. Earlier related work have focused on serial methods, while this paper presents a parallel solution which shows that there is a great increase in time if the number of operations is large. Two different models of the environment and the industrial robot are presented, the first is Octrees at different resolutions, the second is a point cloud representation. The relative merits of the two different world model representations are shown. In particular, the experimental results show the potential of adapting the resolution of the robot and environment models to the task at hand.

  3. Artificial Vision in 3D Perspective. For Object Detection On Planes, Using Points Clouds.

    Directory of Open Access Journals (Sweden)

    Catalina Alejandra Vázquez Rodriguez

    2014-02-01

    Full Text Available In this paper, we talk about an algorithm of artificial vision for the robot Golem - II + with which to analyze the environment the robot, for the detection of planes and objects in the scene through point clouds, which were captured with kinect device, possible objects and quantity, distance and other characteristics. Subsequently the "clusters" are grouped to identify whether they are located on the same surface, in order to calculate the distance and the slope of the planes relative to the robot, and finally each object separately analyzed to see if it is possible to take them, if they are empty surfaces, may leave objects on them, long as feasible considering a distance, ignoring false positives as the walls and floor, which for these purposes are not of interest since it is not possible to place objects on the walls and floor are out of range of the robot's arms.

  4. Palm-Sized Device for Point-of-Care Ebola Detection.

    Science.gov (United States)

    Ahrberg, Christian D; Manz, Andreas; Neužil, Pavel

    2016-05-01

    We show the utilization of a recently developed cellphone-sized real-time polymerase chain reaction (PCR) device to detect Ebola virus RNA using single-step reverse transcription PCR (RT-PCR). The device was shown to concurrently perform four PCRs, each with a sample volume of 100 nL: one positive control with both Ebola and GAPDH RNA and one negative control. The last two positions were used to measure the GAPDH and the Ebola content of a sample. A comparison of threshold cycles (CT) from the two samples provided relative quantification. The entire process, which consisted of reverse transcription, PCR amplification, and melting curve analysis (MCA), was conducted in less than 37 min. The next step will be integration with a sample preparation unit to form an integrated sample-to-answer system for point-of-care infectious disease diagnostics. PMID:27064314

  5. Exploring Permission-Induced Risk in Android Applications for Malicious Application Detection

    KAUST Repository

    Wang, Wei

    2014-10-07

    Android has been a major target of malicious applications (malapps). How to detect and keep the malapps out of the app markets is an ongoing challenge. One of the central design points of Android security mechanism is permission control that restricts the access of apps to core facilities of devices. However, it imparts a significant responsibility to the app developers with regard to accurately specifying the requested permissions and to the users with regard to fully understanding the risk of granting certain combinations of permissions. Android permissions requested by an app depict the app\\'s behavioral patterns. In order to help understanding Android permissions, in this paper, we explore the permission-induced risk in Android apps on three levels in a systematic manner. First, we thoroughly analyze the risk of an individual permission and the risk of a group of collaborative permissions. We employ three feature ranking methods, namely, mutual information, correlation coefficient, and T-test to rank Android individual permissions with respect to their risk. We then use sequential forward selection as well as principal component analysis to identify risky permission subsets. Second, we evaluate the usefulness of risky permissions for malapp detection with support vector machine, decision trees, as well as random forest. Third, we in depth analyze the detection results and discuss the feasibility as well as the limitations of malapp detection based on permission requests. We evaluate our methods on a very large official app set consisting of 310 926 benign apps and 4868 real-world malapps and on a third-party app sets. The empirical results show that our malapp detectors built on risky permissions give satisfied performance (a detection rate as 94.62% with a false positive rate as 0.6%), catch the malapps\\' essential patterns on violating permission access regulations, and are universally applicable to unknown malapps (detection rate as 74.03%).

  6. Knowledge Base Approach for 3D Objects Detection in Point Clouds Using 3D Processing and Specialists Knowledge

    OpenAIRE

    Ben Hmida, Helmi; Cruz, Christophe; Boochs, Frank; Nicolle, Christophe

    2013-01-01

    International audience This paper presents a knowledge-based detection of objects approach using the OWL ontology language, the Semantic Web Rule Language, and 3D processing built-ins aiming at combining geometrical analysis of 3D point clouds and specialist's knowledge. Here, we share our experience regarding the creation of 3D semantic facility model out of unorganized 3D point clouds. Thus, a knowledge-based detection approach of objects using the OWL ontology language is presented. Thi...

  7. Rockfall detection from terrestrial LiDAR point clouds: A clustering approach using R

    Directory of Open Access Journals (Sweden)

    Marj Tonini

    2014-06-01

    Full Text Available In this study we analyzed a series of terrestrial LiDAR point clouds acquired over a cliff in Puigcercos (Catalonia, Spain. The objective was to detect and extract individual rockfall events that occurred during a time span of six months and to investigate their spatial distribution. To this end local and global cluster algorithms were applied. First we used the nearest neighbor clutter removal (NNCR method in combination with the expectation-maximization (EM algorithm to separate feature points from clutter; then a density based algorithm (DBSCAN allowed us to isolate the single cluster features which represented the rockfall events. Finally we estimated the Ripley's K-function to analyze the global spatial pattern of the identified rockfalls. The computations for the cluster analyses were carried out using R free software for statistical computing and graphics. The local cluster analysis allowed a proper identification and characterization of more than 600 rockfalls. The global spatial pattern analysis showed that these rockfalls were clustered and provided the range of distances at which these events tend to be aggregated.

  8. A comparative study of the various electrometric end point detections in oxidimetric estimations of uranium

    International Nuclear Information System (INIS)

    In view of the highly intense beta-gamma activity levels of solutions from different streams from reprocessing plants of Fast Reactor Fuels, a programme for remote adaptations of analytical techniques for estimations of uranium, plutonium, thorium and free acidity has been initiated at the Reactor Research Centre, Kalpakkam. As first part of this programme, various electrometric end point detections for oxidimetric determination of uranium are compared for their precisions with a well evaluated standard potentiometric technique. Those methods which are most suitable for remote manipulations are chosen for the development programme. Analytical procedures thus developed require only very little volume of reagents and generate low volumes of ''active wastes''. The modifications involve increasing the acidity of the diluting reagent to 4 and 8 N sulphuric acid, adding 10% vanadyl sulphate and allowing a standing time of 7 minutes after dilution. Improved precisions and easier identification of end points are observed as a result of these modifications. Also the increased acidity of the diluent prevents gelation and polymerisation of plutonium when present. Zero current potentiometry employing platinum indicator-tungsten reference electrodes is introduced for the first time in uranium estimation. This method, as well as two methods, voltametry and biamperometry using gold electrodes are found to show improved precisions than the said standard method. (A.K.)

  9. ASTRO-F\\/FIS Observing Simulation I. Detection Limits for Point Sources

    CERN Document Server

    Jeong, W S; Lee, H M; Nakagawa, T; Sohn, J; Ahn, I; Yamamura, I; Watanabe, M; Kawada, M K; Shibai, H; Jeong, Woong-Seob; Pak, Soojong; Lee, Hyung Mok; Nakagawa, Takao; Sohn, Jungjoo; Ahn, Insun; Yamamura, Issei; Watanabe, Masaru; Kawada, Mitsunobu; Shibai, Hiroshi

    2002-01-01

    We describe the observing simulation software FISVI (FIS Virtual Instrument), which was developed for the Far-Infrared Surveyor (FIS) that will be on the Japanese infrared astronomy mission ASTRO-F. The FISVI has two purposes: one is to check the specifications and performances of the ASTRO-F/FIS as a whole, and the other is to prepare input data sets for the data analysis softwares prior to launch. In the FISVI, a special care was taken by introducing the `Compiled PSF (Point Spread Function)' to optimise inevitable but time-consuming convolution processes. With the Compiled PSF, we reduce the computation time by an order of magnitude. The photon and readout noises are included in the simulations. We estimate the detection limits for point sources from the simulation of virtual patches of the sky mostly consisting of distant galaxies. We studied the importance of the source confusion for simple power-law models for N(>S), the number of sources brighter than S. We found that source confusion plays a dominant ...

  10. Automatic Detection and Segmentation of Columns in As-Built Buildings from Point Clouds

    Directory of Open Access Journals (Sweden)

    Lucía Díaz-Vilariño

    2015-11-01

    Full Text Available Over the past few years, there has been an increasing need for tools that automate the processing of as-built 3D laser scanner data. Given that a fast and active dimensional analysis of constructive components is essential for construction monitoring, this paper is particularly focused on the detection and segmentation of columns in building interiors from incomplete point clouds acquired with a Terrestrial Laser Scanner. The methodology addresses two types of columns: round cross-section and rectangular cross-section. Considering columns as vertical elements, the global strategy for segmentation involves the rasterization of a point cloud onto the XY plane and the implementation of a model-driven approach based on the Hough Transform. The methodology is tested in two real case studies, and experiments are carried out under different levels of data completeness. The results show the robustness of the methodology to the presence of clutter and partial occlusion, typical in building indoors, even though false positives can be obtained if other elements with the same shape and size as columns are present in the raster.

  11. Event Detection at Vehicle Location Points using Spatial Time Invariant Model

    Directory of Open Access Journals (Sweden)

    R.C.Karpagalakshmi

    2014-05-01

    Full Text Available The localization and recognition of moving objects from single monocular intensity images has been a popular issue in image analysis and computer vision over many years. It is also one of the fundamental crisis in model based vehicle localization and recognition. The recently used scheme is model based on simple object recognition and localization of road vehicles using the position and orientation of vehicle image data. But the drawback of the approach is that the shape of the vehicle and its pose varies in multiple junction coordination, the model based recognition is an inefficient one. To overcome the issues, our first work implemented a surveillance image object recognition and localization using improved local gradient model. The vehicle-object shape recognition and pose recovery in the traffic junction is carried out for varied traffic densities. But the drawback of the approach is that it considers only the vehicle shape and pose variations in the road network and does not discuss about the occurrences of event at the vehicle junction points. Now we have to focus on the process of occurrences of event like accident met at traffic junctions. For this, in this work, spatial time invariant model is introduced to measure the event occurrences of the vehicle traffic location points. The event which has been takes place is recorded as the reference context for standardization of the traffic modality. With the reference context, the detector can easily find out the reason of the event takes place. An experimental evaluation is carried out to estimate the performance of the proposed event detection at vehicle location points using spatial time invariant model (EDSTIM in terms of spatial events, multiple time scales, traffic controlling time and compared with an existing model based on simple object recognition and localization and the previous work Surveillance of Vehicle Object Recognition and Localization.

  12. A novel method for fast Change-Point detection on simulated time series and electrocardiogram data.

    Directory of Open Access Journals (Sweden)

    Jin-Peng Qi

    Full Text Available Although Kolmogorov-Smirnov (KS statistic is a widely used method, some weaknesses exist in investigating abrupt Change Point (CP problems, e.g. it is time-consuming and invalid sometimes. To detect abrupt change from time series fast, a novel method is proposed based on Haar Wavelet (HW and KS statistic (HWKS. First, the two Binary Search Trees (BSTs, termed TcA and TcD, are constructed by multi-level HW from a diagnosed time series; the framework of HWKS method is implemented by introducing a modified KS statistic and two search rules based on the two BSTs; and then fast CP detection is implemented by two HWKS-based algorithms. Second, the performance of HWKS is evaluated by simulated time series dataset. The simulations show that HWKS is faster, more sensitive and efficient than KS, HW, and T methods. Last, HWKS is applied to analyze the electrocardiogram (ECG time series, the experiment results show that the proposed method can find abrupt change from ECG segment with maximal data fluctuation more quickly and efficiently, and it is very helpful to inspect and diagnose the different state of health from a patient's ECG signal.

  13. Immunosensor for the ultrasensitive and quantitative detection of bladder cancer in point of care testing.

    Science.gov (United States)

    Chuang, Cheng-Hsin; Du, Yi-Chun; Wu, Ting-Feng; Chen, Cheng-Ho; Lee, Da-Huei; Chen, Shih-Min; Huang, Ting-Chi; Wu, Hsun-Pei; Shaikh, Muhammad Omar

    2016-10-15

    An ultrasensitive and real-time impedance based immunosensor has been fabricated for the quantitative detection of Galectin-1 (Gal-1) protein, a biomarker for the onset of multiple oncological conditions, especially bladder cancer. The chip consists of a gold annular interdigitated microelectrode array (3×3 format with a sensing area of 200µm) patterned using standard microfabrication processes, with the ability to electrically address each electrode individually. To improve sensitivity and immobilization efficiency, we have utilized nanoprobes (Gal-1 antibodies conjugated to alumina nanoparticles through silane modification) that are trapped on the microelectrode surface using programmable dielectrophoretic manipulations. The limit of detection of the immunosensor for Gal-1 protein is 0.0078mg/ml of T24 (Grade III) cell lysate in phosphate buffered saline, artificial urine and human urine samples. The normalized impedance variations show a linear dependence on the concentration of cell lysate present while specificity is demonstrated by comparing the immunosensor response for two different grades of bladder cancer cell lysates. We have also designed a portable impedance analyzing device to connect the immunosensor for regular checkup in point of care testing with the ability to transfer data over the internet using a personal computer. We believe that this diagnostic system would allow for improved public health monitoring and aid in early cancer diagnosis. PMID:26777732

  14. Sensitive ergotamine determination in pharmaceuticals and biological samples using cloud point preconcentration and spectrofluorimetric detection.

    Science.gov (United States)

    Wang, Chien C; Fernández, Liliana P; Gómez, María Roxana

    2013-03-20

    A new cloud point extraction (CPE) method for ergotamine analysis using fluorimetric detection is described. Ergotamine from an aqueous solution was preconcentrated into a smaller surfactant-rich phase using nonionic surfactant polyoxyethylene(7.5)nonylphenylether (PONPE 7.5). Differently from the conventional CPE procedure in which the resulting surfactant-rich phase is diluted by a fluidificant before its analysis, in this method the fluorescence measurements were carried out directly onto the undiluted surfactant-rich phase. The high viscosity provided by the undiluted surfactant rich phase greatly improved the fluorescence emission of ergotamine, leading to a total enhancement factor of 1325. This spectral advantage plus the preconcentration factor achieved, contributed to the method sensitivity allowing the ergotamine determination at trace level concentration. Under optimal experimental conditions, a linear calibration curve was obtained from 3.81×10(-7) to 1.10μgmL(-1), with detection and quantification limits of 0.11 and 0.38pgmL(-1), respectively. The accuracy and versatility of the present methodology were proved by analyzing ergotamine in real samples of different natures such as pharmaceuticals, urine and saliva. PMID:23473254

  15. THE CLINICAL APPLICATIONS FOR AUTOMATIC DETECTION OF EXUDATES

    OpenAIRE

    K. Wisaeng; N. Hiransakolwong; E. Pothiruk

    2014-01-01

    Nowadays, the retinal imaging technology has been widely used for segmenting and detecting the exudates in diabetic retinopathy patients. Unfortunately, the retinal images in Thailand are poor-quality images. Therefore, detecting of exudates in a large number by screening programs, are very expensive in professional time and may cause human error. In this study, the clinical applications for detection of exudates from the poor quality retinal image are presented. An application incorporating ...

  16. A Multiplexed Diagnostic Platform for Point-of-Care Pathogen Detection

    Energy Technology Data Exchange (ETDEWEB)

    Regan, J F; Letant, S E; Adams, K L; Mahnke, R C; Nguyen, N T; Dzenitis, J M; Hindson, B J; Hadley, D R; Makarewicz, T J; Henderer, B D; Breneman, J W; Tammero, L F; Ortiz, J I; Derlet, R W; Cohen, S; Colston, W W; McBride, M T; Birch, J M

    2008-02-04

    We developed an automated point-of-care diagnostic instrument that is capable of analyzing nasal swab samples for the presence of respiratory diseases. This robust instrument, called FluIDx, performs autonomous multiplexed RT-PCR reactions that are analyzed by microsphere xMAP technology. We evaluated the performance of FluIDx, in comparison rapid tests specific for influenza and respiratory syncytial virus, in a clinical study performed at the UC Davis Medical Center. The clinical study included samples positive for RSV (n = 71), influenza A (n = 16), influenza B (n = 4), adenovirus (n = 5), parainfluenza virus (n = 2), and 44 negative samples, according to a composite reference method. FluIDx and the rapid tests detected 85.9% and 62.0% of the RSV positive samples, respectively. Similar sensitivities were recorded for the influenza B samples; whereas the influenza A samples were poorly detected, likely due to the utilization of an influenza A signature that did not accurately match currently circulating influenza A strains. Data for all pathogens were compiled and indicate that FluIDx is more sensitive than the rapid tests, detecting 74.2% (95% C.I. of 64.7-81.9%) of the positive samples in comparison to 53.6% (95% C.I. of 43.7-63.2%) for the rapid tests. The higher sensitivity of FluIDx was partially offset by a lower specificity, 77.3% versus 100.0%. Overall, these data suggest automated flow-through PCR-based instruments that perform multiplexed assays can successfully screen clinical samples for infectious diseases.

  17. Orthogonal projection of points in CAD/CAM applications: an overview

    Directory of Open Access Journals (Sweden)

    Kwanghee Ko

    2014-04-01

    Full Text Available This paper aims to review methods for computing orthogonal projection of points onto curves and surfaces, which are given in implicit or parametric form or as point clouds. Special emphasis is place on orthogonal projection onto conics along with reviews on orthogonal projection of points onto curves and surfaces in implicit and parametric form. Except for conics, computation methods are classified into two groups based on the core approaches: iterative and subdivision based. An extension of orthogonal projection of points to orthogonal projection of curves onto surfaces is briefly explored. Next, the discussion continues toward orthogonal projection of points onto point clouds, which spawns a different branch of algorithms in the context of orthogonal projection. The paper concludes with comments on guidance for an appropriate choice of methods for various applications.

  18. An angle-based subspace anomaly detection approach to high-dimensional data: With an application to industrial fault detection

    International Nuclear Information System (INIS)

    The accuracy of traditional anomaly detection techniques implemented on full-dimensional spaces degrades significantly as dimensionality increases, thereby hampering many real-world applications. This work proposes an approach to selecting meaningful feature subspace and conducting anomaly detection in the corresponding subspace projection. The aim is to maintain the detection accuracy in high-dimensional circumstances. The suggested approach assesses the angle between all pairs of two lines for one specific anomaly candidate: the first line is connected by the relevant data point and the center of its adjacent points; the other line is one of the axis-parallel lines. Those dimensions which have a relatively small angle with the first line are then chosen to constitute the axis-parallel subspace for the candidate. Next, a normalized Mahalanobis distance is introduced to measure the local outlier-ness of an object in the subspace projection. To comprehensively compare the proposed algorithm with several existing anomaly detection techniques, we constructed artificial datasets with various high-dimensional settings and found the algorithm displayed superior accuracy. A further experiment on an industrial dataset demonstrated the applicability of the proposed algorithm in fault detection tasks and highlighted another of its merits, namely, to provide preliminary interpretation of abnormality through feature ordering in relevant subspaces. - Highlights: • An anomaly detection approach for high-dimensional reliability data is proposed. • The approach selects relevant subspaces by assessing vectorial angles. • The novel ABSAD approach displays superior accuracy over other alternatives. • Numerical illustration approves its efficacy in fault detection applications

  19. Automatic Detection and Classification of Pole-Like Objects in Urban Point Cloud Data Using an Anomaly Detection Algorithm

    OpenAIRE

    Borja Rodríguez-Cuenca; Silverio García-Cortés; Celestino Ordóñez; Maria C. Alonso

    2015-01-01

    Detecting and modeling urban furniture are of particular interest for urban management and the development of autonomous driving systems. This paper presents a novel method for detecting and classifying vertical urban objects and trees from unstructured three-dimensional mobile laser scanner (MLS) or terrestrial laser scanner (TLS) point cloud data. The method includes an automatic initial segmentation to remove the parts of the original cloud that are not of interest for detecting vertical o...

  20. Explosives detection with applications to landmines

    International Nuclear Information System (INIS)

    Modern mines have been made difficult to detect by conventional means such as magnetic detection. The problem is not only that there is often only a small amount of metal in the mine but that the war zone may contain an enormous amount of metal pieces from other weapons. Thus the problem is not just one of detection, but of developing methods to discriminate between many kinds of background and clutter that are present. One of techniques is the use of fast neutrons to probe material with subsequent spectrometry of gamma rays produced by inelastic neutron interactions. Another approach is the use of an infrared camera to detect mines after heating soil with a large heater. Certain advantages has Nuclear Quadrupole Resonance to detect nitrogen in compounds such as TNT. Use of remote controlled mechanical devices to detonate mines can also be considered. It is important to note that no single device will solve the problem and therefore it will be more effective to build devices specific to problem

  1. Detection of oscillatory components in noise signals and its application to fast detection of sodium boiling in LMFBR's

    International Nuclear Information System (INIS)

    In general, the surveillance of technical plants is performed by observating the mean value of measured signals. In this method not all information included in these signals is used. On the other hand - for example in a reactor - disturbances are possible which generate small oscillatory components in the measured signals. In general, these oscillatory components do not influence the mean value of the signals and consequently do not activate the conventional control system; however they can be found by analysis of the signal's noise component. For the detection of these oscillatory signals the observation of the frequency spectra of the noise signals is particularly advantageous because they produce peaks at the oscillation frequencies. In this paper a new detection system for the fast detection of suddenly appearing peaks in the frequency spectra of noise signals is presented. The prototype of a compact detection unit was developed which continuously computes the power spectral density (PSD) of noise signals and simultaneously supervises the PSD for peaks in the relevant frequency range. The detection method is not affected by the frequency dependance of the PSD and is applicable to any noise signal. General criteria were developed to enable the determination of the optimal detection system and its sensitivity. The upper limits of false alarm rate and detection time were taken into account. The detection criteria are applicable to all noise signals with approximately normally distributed amplitudes. Theoretical results were confirmed in a number of experiments; special experimental and theoretical parameter studies were done for the optimal detection of sodium boiling in LMFBR's. Computations based on these results showed that local and integral sodium boiling can be detected in a wide core range of SNR 300 by observing fluctuations of the neutron flux. In this connection it is important to point out that no additional core instrumentation is necessary because the

  2. Solar thermal power systems point-focusing thermal and electric applications projects. Volume 1: Executive summary

    Science.gov (United States)

    Marriott, A.

    1980-01-01

    The activities of the Point-Focusing Thermal and Electric Applications (PETEA) project for the fiscal year 1979 are summarized. The main thrust of the PFTEA Project, the small community solar thermal power experiment, was completed. Concept definition studies included a small central receiver approach, a point-focusing distributed receiver system with central power generation, and a point-focusing distributed receiver concept with distributed power generation. The first experiment in the Isolated Application Series was initiated. Planning for the third engineering experiment series, which addresses the industrial market sector, was also initiated. In addition to the experiment-related activities, several contracts to industry were let and studies were conducted to explore the market potential for point-focusing distributed receiver (PFDR) systems. System analysis studies were completed that looked at PFDR technology relative to other small power system technology candidates for the utility market sector.

  3. Detecting Non-Dominated Extreme Points for Multiple Objective Linear Programming

    Directory of Open Access Journals (Sweden)

    S. F. Tantawy

    2007-01-01

    Full Text Available Efficient extreme points in decision space of multiple objective linear programming (MOLP may not map to non dominated extreme points in objective space under the linear mapping, condition that efficient extreme points have a non dominated extreme is given, the important of this study is that the decision-Maker may depends on extreme points of the set of the objective space than that of the decision space since they have fewer extreme points.

  4. An Application of Fixed Point Theory to a Nonlinear Differential Equation

    OpenAIRE

    Farajzadeh, A. P.; A. Kaewcharoen; Plubtieng, S.

    2014-01-01

    We introduce a new family of mappings on $[\\mathrm{0},+\\infty )$ by relaxing the nondecreasing condition on the mappings and by using the properties of this new family we present some fixed point theorems for $\\alpha $ - $\\psi $ -contractive-type mappings in the setting of complete metric spaces. By applying our obtained results, we also assure the fixed point theorems in partially ordered complete metric spaces and as an application of the main results we provide an existence theorem for a n...

  5. Mobile platform for acoustic mine detection applications

    Science.gov (United States)

    Libbey, Brad; Fenneman, Douglas; Burns, Brian

    2005-06-01

    Researchers in academia have successfully demonstrated acoustic landmine detection techniques. These typically employ acoustic or seismic sources to induce vibration in the mine/soil system, and use vibration sensors such as laser vibrometers or geophones to measure the resultant surface motion. These techniques exploit the unique mechanical properties of landmines to discriminate the vibration response of a buried mine from an off-target measurement. The Army requires the ability to rapidly and reliably scan an area for landmines and is developing a mobile platform at NVESD to meet this requirement. The platform represents an initial step toward the implementation of acoustic mine detection technology on a representative field vehicle. The effort relies heavily on the acoustic mine detection cart system developed by researchers at the University of Mississippi and Planning Systems, Inc. The NVESD platform consists of a John Deere E-gator configured with a robotic control system to accurately position the vehicle. In its present design, the E-gator has been outfitted with an array of laser vibrometers and a bank of loudspeakers. Care has been taken to ensure that the vehicle"s mounting hardware and data acquisition algorithms are sufficiently robust to accommodate the implementation of other sensor modalities. A thorough discussion of the mobile platform from its inception to its present configuration will be provided. Specific topics to be addressed include the vehicle"s control and data acquisition systems. Preliminary results from acoustic mine detection experiments will also be presented.

  6. Explosive Detection in Aviation Applications Using CT

    Energy Technology Data Exchange (ETDEWEB)

    Martz, H E; Crawford, C R

    2011-02-15

    CT scanners are deployed world-wide to detect explosives in checked and carry-on baggage. Though very similar to single- and dual-energy multi-slice CT scanners used today in medical imaging, some recently developed explosives detection scanners employ multiple sources and detector arrays to eliminate mechanical rotation of a gantry, photon counting detectors for spectral imaging, and limited number of views to reduce cost. For each bag scanned, the resulting reconstructed images are first processed by automated threat recognition algorithms to screen for explosives and other threats. Human operators review the images only when these automated algorithms report the presence of possible threats. The US Department of Homeland Security (DHS) has requirements for future scanners that include dealing with a larger number of threats, higher probability of detection, lower false alarm rates and lower operating costs. One tactic that DHS is pursuing to achieve these requirements is to augment the capabilities of the established security vendors with third-party algorithm developers. A third-party in this context refers to academics and companies other than the established vendors. DHS is particularly interested in exploring the model that has been used very successfully by the medical imaging industry, in which university researchers develop algorithms that are eventually deployed in commercial medical imaging equipment. The purpose of this paper is to discuss opportunities for third-parties to develop advanced reconstruction and threat detection algorithms.

  7. Explosive Detection in Aviation Applications Using CT

    International Nuclear Information System (INIS)

    CT scanners are deployed world-wide to detect explosives in checked and carry-on baggage. Though very similar to single- and dual-energy multi-slice CT scanners used today in medical imaging, some recently developed explosives detection scanners employ multiple sources and detector arrays to eliminate mechanical rotation of a gantry, photon counting detectors for spectral imaging, and limited number of views to reduce cost. For each bag scanned, the resulting reconstructed images are first processed by automated threat recognition algorithms to screen for explosives and other threats. Human operators review the images only when these automated algorithms report the presence of possible threats. The US Department of Homeland Security (DHS) has requirements for future scanners that include dealing with a larger number of threats, higher probability of detection, lower false alarm rates and lower operating costs. One tactic that DHS is pursuing to achieve these requirements is to augment the capabilities of the established security vendors with third-party algorithm developers. A third-party in this context refers to academics and companies other than the established vendors. DHS is particularly interested in exploring the model that has been used very successfully by the medical imaging industry, in which university researchers develop algorithms that are eventually deployed in commercial medical imaging equipment. The purpose of this paper is to discuss opportunities for third-parties to develop advanced reconstruction and threat detection algorithms.

  8. Change-point detection in the historical hurricane number time-series: why can't we detect change-points at US landfall?

    CERN Document Server

    Nzerem, K; Laepple, T; Nzerem, Kechi; Jewson, Stephen; Laepple, Thomas

    2006-01-01

    The time series of the number of hurricanes per year in the Atlantic basin shows a clear change of level between 1994 and 1995. The time series of the number of hurricanes that make landfall in the US, however, does not show the same obvious change of level. Prima-facie this seems rather surprising, given that the landfalling hurricanes are a subset of the basin hurricanes. We investigate whether it really should be considered surprising or whether there is a simple statistical explanation for the disappearance of this change-point at landfall.

  9. Improved Genetic Algorithm Application in Textile Defect Detection

    Institute of Scientific and Technical Information of China (English)

    GENG Zhao-feng; Li Bei-bei; ZHAO Zhi-hong

    2007-01-01

    Based on an efficient improved genetic algorithm,a pattern recognition approach is represented for textile defects inspection. An image process is developed to automatically detect the drawbacks on textile caused by three circumstances: break, dual, and jump of yams. By statistic method, some texture feature values of the image with defects points can be achieved. Therefore, the textile defects are classified properly. The advanced process of the defect image is done. Image segmentation is realized by an improved genetic algorithm to detect the defects. This method can be used to automatically classify and detect textile defects. According to different users' requirements, ifferent types of textile material can be detected.

  10. Detection of cut-off point for rapid automized naming test in good readers and dyslexics

    Directory of Open Access Journals (Sweden)

    Zahra Soleymani

    2014-01-01

    Full Text Available Background and Aim: Rapid automized naming test is an appropriate tool to diagnose learning disability even before teaching reading. This study aimed to detect the cut-off point of this test for good readers and dyslexics.Methods: The test has 4 parts including: objects, colors, numbers and letters. 5 items are repeated on cards randomly for 10 times. Children were asked to name items rapidly. We studied 18 dyslexic students and 18 age-matched good readers between 7 and 8 years of age at second and third grades of elementary school; they were recruited by non-randomize sampling into 2 groups: children with developmental dyslexia from learning disabilities centers with mean age of 100 months, and normal children with mean age of 107 months from general schools in Tehran. Good readers selected from the same class of dyslexics.Results: The area under the receiver operating characteristic curve was 0.849 for letter naming, 0.892 for color naming, 0.971 for number naming, 0.887 for picture naming, and 0.965 totally. The overall sensitivity and specificity was 1 and was 0.79, respectively. The highest sensitivity and specificity were related to number naming (1 and 0.90, respectively.Conclusion: Findings showed that the rapid automized naming test could diagnose good readers from dyslexics appropriately.

  11. Bioaerosol standoff detection and correlation assessment with concentration and viability point sensors

    Science.gov (United States)

    Buteau, Sylvie; Simard, Jean-Robert; Rowsell, Susan; Roy, Gilles

    2010-10-01

    A standoff bioaerosol sensor based on intensified range-gated spectrometric detection of Laser Induced Fluorescence was used to spectrally characterize bioaerosol simulants during in-chamber and open-air releases at Suffield, Canada, in August 2008 from a standoff position. In total, 42 in-chamber Bacillus atrophaeus (formerly Bacillus subtilis var globigii; BG) cloud and 27 open-air releases of either BG, Pantoea agglomerans (formerly Erwinia herbicola; EH), MS2 and ovalbumin (OV) were generated. The clouds were refereed by different point sensors including Aerodynamic Particle Sizer (APS) and slit or impingers samplers. The APS monitored the particle size distribution and concentration and the samplers characterized the viable portion of the cloud. The extracted spectral signatures show robustness to different degree. The correlation assessment showed good results in most cases where the LIF signal to noise ratio was significant. The sensor 4σ sensitivity was evaluated to 1 300, 600, 100 and 30 ppl for BG, OV, MS2 and EH respectively. Correlation results are presented by plotting the SINBAHD metric versus the corresponding particle concentration, in which case, the obtained slope is proportional to the material fluorescence cross-section. The different acquired signal is hence compared in terms of their fluorescence cross-section additionally to their spectral characteristics.

  12. Isoelectric point determination of live polioviruses by capillary isoelectric focusing with whole column imaging detection.

    Science.gov (United States)

    Thomassen, Yvonne E; van Eikenhorst, Gerco; van der Pol, Leo A; Bakker, Wilfried A M

    2013-06-18

    Using a capillary isoelectric focusing-whole column imaging detection (CIEF-WCID) method, the isoelectric points (pI) of complete intact polioviruses were determined. The polioviruses that were analyzed are the commonly used viruses for the production of inactivated polio vaccines (IPV)-Mahoney (type 1), MEF (type 2), and Saukett (type 3)-as well as for attenuated oral polio vaccines (OPV) and Sabin types 1, 2, and 3. A method for analyzing biological hazardous components (biological safety level 2) was set up for the CIEF-WCID analyzer used. This method is based on closed circuits. The determined pI's were 6.2 for Mahoney, 6.7 for MEF-1, and 5.8 for Saukett. The pI's of Sabin types 1, 2, and 3 viruses were 7.4, 7.2, and 6.3, respectively. Resolution of the virus peaks was shown to be reproducible. Using this adjusted CIEF-WCID technique, the pI of biologically hazardous components like toxins or viruses can be determined, which is beneficial for the development of vaccine production methods among others. PMID:23672432

  13. Application of point system in the project control of Ling'ao Nuclear Power Station

    International Nuclear Information System (INIS)

    Schedule control and cost control are very complicated issues even we set up the detail schedules and engineering measurements requirements for erection of a nuclear power project. In order to solve these problems, a Point System is used in Ling Ao (LA) Nuclear Power Project. This paper introduces the method. The Point System is a measurement system of workload. The measurement unit of any erection works is a Point only. A Point of workload is defined as the equivalent measurement quantities, which could be completed by a relevant skill worker within an hour. A set of procedure manuals for different installations has been set up. The calculation models of equipment installation, piping, cabling are addressed for example in the paper. The application of the Point System in the schedule control is shown in the paper. The following issues are highlighted: to define the duration of a piping activity in the Project Level 2 Schedule, to draught the curves of Point Schedules for different erection fields, to analyze the productive efficiency, to define erection quota of each month for different erection teams, to follow up the erection progress on site. The application of the Point System in the payment of erection contract is outlined. The calculation formula of a monthly payment is given. The advantage of the payment calculation method is discussed, for example, more accurate, very easy and clearly to check the measurement quantities completed on site, to control lump-sum cost. (authors)

  14. Modeling of delamination in carbon/epoxy composite laminates under four point bending for damage detection and sensor placement optimization

    Science.gov (United States)

    Adu, Stephen Aboagye

    Laminated carbon fiber-reinforced polymer composites (CFRPs) possess very high specific strength and stiffness and this has accounted for their wide use in structural applications, most especially in the aerospace industry, where the trade-off between weight and strength is critical. Even though they possess much larger strength ratio as compared to metals like aluminum and lithium, damage in the metals mentioned is rather localized. However, CFRPs generate complex damage zones at stress concentration, with damage progression in the form of matrix cracking, delamination and fiber fracture or fiber/matrix de-bonding. This thesis is aimed at performing; stiffness degradation analysis on composite coupons, containing embedded delamination using the Four-Point Bend Test. The Lamb wave-based approach as a structural health monitoring (SHM) technique is used for damage detection in the composite coupons. Tests were carried-out on unidirectional composite coupons, obtained from panels manufactured with pre-existing defect in the form of embedded delamination in a laminate of stacking sequence [06/904/0 6]T. Composite coupons were obtained from panels, fabricated using vacuum assisted resin transfer molding (VARTM), a liquid composite molding (LCM) process. The discontinuity in the laminate structure due to the de-bonding of the middle plies caused by the insertion of a 0.3 mm thick wax, in-between the middle four (4) ninety degree (90°) plies, is detected using lamb waves generated by surface mounted piezoelectric (PZT) actuators. From the surface mounted piezoelectric sensors, response for both undamaged (coupon with no defect) and damaged (delaminated coupon) is obtained. A numerical study of the embedded crack propagation in the composite coupon under four-point and three-point bending was carried out using FEM. Model validation was then carried out comparing the numerical results with the experimental. Here, surface-to-surface contact property was used to model the

  15. A hierarchical model combining distance sampling and time removal to estimate detection probability during avian point counts

    Science.gov (United States)

    Amundson, Courtney L.; Royle, J. Andrew; Handel, Colleen M.

    2014-01-01

    Imperfect detection during animal surveys biases estimates of abundance and can lead to improper conclusions regarding distribution and population trends. Farnsworth et al. (2005) developed a combined distance-sampling and time-removal model for point-transect surveys that addresses both availability (the probability that an animal is available for detection; e.g., that a bird sings) and perceptibility (the probability that an observer detects an animal, given that it is available for detection). We developed a hierarchical extension of the combined model that provides an integrated analysis framework for a collection of survey points at which both distance from the observer and time of initial detection are recorded. Implemented in a Bayesian framework, this extension facilitates evaluating covariates on abundance and detection probability, incorporating excess zero counts (i.e. zero-inflation), accounting for spatial autocorrelation, and estimating population density. Species-specific characteristics, such as behavioral displays and territorial dispersion, may lead to different patterns of availability and perceptibility, which may, in turn, influence the performance of such hierarchical models. Therefore, we first test our proposed model using simulated data under different scenarios of availability and perceptibility. We then illustrate its performance with empirical point-transect data for a songbird that consistently produces loud, frequent, primarily auditory signals, the Golden-crowned Sparrow (Zonotrichia atricapilla); and for 2 ptarmigan species (Lagopus spp.) that produce more intermittent, subtle, and primarily visual cues. Data were collected by multiple observers along point transects across a broad landscape in southwest Alaska, so we evaluated point-level covariates on perceptibility (observer and habitat), availability (date within season and time of day), and abundance (habitat, elevation, and slope), and included a nested point

  16. Research on infrared dim-point target detection and tracking under sea-sky-line complex background

    Science.gov (United States)

    Dong, Yu-xing; Li, Yan; Zhang, Hai-bo

    2011-08-01

    Target detection and tracking technology in infrared image is an important part of modern military defense system. Infrared dim-point targets detection and recognition under complex background is a difficulty and important strategic value and challenging research topic. The main objects that carrier-borne infrared vigilance system detected are sea-skimming aircrafts and missiles. Due to the characteristics of wide field of view of vigilance system, the target is usually under the sea clutter. Detection and recognition of the target will be taken great difficulties .There are some traditional point target detection algorithms, such as adaptive background prediction detecting method. When background has dispersion-decreasing structure, the traditional target detection algorithms would be more useful. But when the background has large gray gradient, such as sea-sky-line, sea waves etc .The bigger false-alarm rate will be taken in these local area .It could not obtain satisfactory results. Because dim-point target itself does not have obvious geometry or texture feature ,in our opinion , from the perspective of mathematics, the detection of dim-point targets in image is about singular function analysis .And from the perspective image processing analysis , the judgment of isolated singularity in the image is key problem. The foregoing points for dim-point targets detection, its essence is a separation of target and background of different singularity characteristics .The image from infrared sensor usually accompanied by different kinds of noise. These external noises could be caused by the complicated background or from the sensor itself. The noise might affect target detection and tracking. Therefore, the purpose of the image preprocessing is to reduce the effects from noise, also to raise the SNR of image, and to increase the contrast of target and background. According to the low sea-skimming infrared flying small target characteristics , the median filter is used to

  17. Detection of Cast Shadows in Surveillance Applications

    DEFF Research Database (Denmark)

    Erbou, Søren G.; Sørensen, Helge Bjarne Dissing; Stage, Bjarne

    2005-01-01

    Cast shadows from moving objects reduce the general ability of robust classification and tracking of these objects, in outdoor surveillance applications. A method for segmentation of cast shadows is proposed, combining statistical features with a new similarity feature, derived from a physics...

  18. Field application of pathogen detection technologies

    Energy Technology Data Exchange (ETDEWEB)

    Straub, Tim M.; Call, Douglas R.; Bruckner-Lea, Cindy J.; Colburn, Heather A.; Baird, Cheryl L.; Bartholomew, Rachel A.; Ozanich, Richard M.; Jarman, Kristin H.

    2016-06-29

    Over the last 10 years there has been a significant increase in commercial products designed for field-based detection of microbial pathogens. This is due, in part, to the anthrax attacks in the United States in 2001, and the need for first responders to quickly identify the composition of suspected white powders and other potential biothreats. Demand for rapid detection is also driven by the need to ensure safe food, water, and environmental systems. From a technology perspective, rapid identification methods have largely capitalized on PCR and other molecular recognition techniques that can be deployed as robust field instrumentation. Examples of the relevant needs include the ability to: 1) declare a water distribution system free of microbial pathogens after a pipe/main break repair; 2) assess risks of contamination such as when produce production and processing plants are located near concentrated animal feeing operations; 3) evaluate the safety of ready-to-eat products; 4) determine the extent of potential serious disease outbreaks in remote and/or disaster stricken areas where access to clinical laboratories is not an immediate option; and 5) quickly assess credible biological terrorism events. Many of the principles underlying rapid detection methods are derived from methods for environmental microbiology, but there is a dearth of literature describing and evaluating field-based detection systems. Thus, the aims of this chapter are to: 1) summarize the different kinds of commercially available sampling kits and field-based biological detectors; 2) highlight some of the continued challenges of sample preparation to stimulate new research towards minimizing the impact of inhibitors on PCR-based detection systems; 3) describe our general rationale and statistically-based approach for instrument evaluation; 4) provide statistical and spatial guidelines for developing valid sampling plans; and 5) summarize some current needs and emerging technologies. This

  19. Adaptive error detection for HDR/PDR brachytherapy: Guidance for decision making during real-time in vivo point dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Kertzscher, Gustavo, E-mail: guke@dtu.dk; Andersen, Claus E., E-mail: clan@dtu.dk [Centre for Nuclear Technologies, Technical University of Denmark, DTU Nutech, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Tanderup, Kari, E-mail: karitand@rm.dk [Department of Oncology, Aarhus University Hospital and Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus (Denmark)

    2014-05-15

    Purpose: This study presents an adaptive error detection algorithm (AEDA) for real-timein vivo point dosimetry during high dose rate (HDR) or pulsed dose rate (PDR) brachytherapy (BT) where the error identification, in contrast to existing approaches, does not depend on an a priori reconstruction of the dosimeter position. Instead, the treatment is judged based on dose rate comparisons between measurements and calculations of the most viable dosimeter position provided by the AEDA in a data driven approach. As a result, the AEDA compensates for false error cases related to systematic effects of the dosimeter position reconstruction. Given its nearly exclusive dependence on stable dosimeter positioning, the AEDA allows for a substantially simplified and time efficient real-time in vivo BT dosimetry implementation. Methods: In the event of a measured potential treatment error, the AEDA proposes the most viable dosimeter position out of alternatives to the original reconstruction by means of a data driven matching procedure between dose rate distributions. If measured dose rates do not differ significantly from the most viable alternative, the initial error indication may be attributed to a mispositioned or misreconstructed dosimeter (false error). However, if the error declaration persists, no viable dosimeter position can be found to explain the error, hence the discrepancy is more likely to originate from a misplaced or misreconstructed source applicator or from erroneously connected source guide tubes (true error). Results: The AEDA applied on twoin vivo dosimetry implementations for pulsed dose rate BT demonstrated that the AEDA correctly described effects responsible for initial error indications. The AEDA was able to correctly identify the major part of all permutations of simulated guide tube swap errors and simulated shifts of individual needles from the original reconstruction. Unidentified errors corresponded to scenarios where the dosimeter position was

  20. Adaptive error detection for HDR/PDR brachytherapy: Guidance for decision making during real-time in vivo point dosimetry

    International Nuclear Information System (INIS)

    Purpose: This study presents an adaptive error detection algorithm (AEDA) for real-timein vivo point dosimetry during high dose rate (HDR) or pulsed dose rate (PDR) brachytherapy (BT) where the error identification, in contrast to existing approaches, does not depend on an a priori reconstruction of the dosimeter position. Instead, the treatment is judged based on dose rate comparisons between measurements and calculations of the most viable dosimeter position provided by the AEDA in a data driven approach. As a result, the AEDA compensates for false error cases related to systematic effects of the dosimeter position reconstruction. Given its nearly exclusive dependence on stable dosimeter positioning, the AEDA allows for a substantially simplified and time efficient real-time in vivo BT dosimetry implementation. Methods: In the event of a measured potential treatment error, the AEDA proposes the most viable dosimeter position out of alternatives to the original reconstruction by means of a data driven matching procedure between dose rate distributions. If measured dose rates do not differ significantly from the most viable alternative, the initial error indication may be attributed to a mispositioned or misreconstructed dosimeter (false error). However, if the error declaration persists, no viable dosimeter position can be found to explain the error, hence the discrepancy is more likely to originate from a misplaced or misreconstructed source applicator or from erroneously connected source guide tubes (true error). Results: The AEDA applied on twoin vivo dosimetry implementations for pulsed dose rate BT demonstrated that the AEDA correctly described effects responsible for initial error indications. The AEDA was able to correctly identify the major part of all permutations of simulated guide tube swap errors and simulated shifts of individual needles from the original reconstruction. Unidentified errors corresponded to scenarios where the dosimeter position was

  1. Effective Generation and Update of a Building Map Database Through Automatic Building Change Detection from LiDAR Point Cloud Data

    Directory of Open Access Journals (Sweden)

    Mohammad Awrangjeb

    2015-10-01

    Full Text Available Periodic building change detection is important for many applications, including disaster management. Building map databases need to be updated based on detected changes so as to ensure their currency and usefulness. This paper first presents a graphical user interface (GUI developed to support the creation of a building database from building footprints automatically extracted from LiDAR (light detection and ranging point cloud data. An automatic building change detection technique by which buildings are automatically extracted from newly-available LiDAR point cloud data and compared to those within an existing building database is then presented. Buildings identified as totally new or demolished are directly added to the change detection output. However, for part-building demolition or extension, a connected component analysis algorithm is applied, and for each connected building component, the area, width and height are estimated in order to ascertain if it can be considered as a demolished or new building-part. Using the developed GUI, a user can quickly examine each suggested change and indicate his/her decision to update the database, with a minimum number of mouse clicks. In experimental tests, the proposed change detection technique was found to produce almost no omission errors, and when compared to the number of reference building corners, it reduced the human interaction to 14% for initial building map generation and to 3% for map updating. Thus, the proposed approach can be exploited for enhanced automated building information updating within a topographic database.

  2. Detection of flow separation and stagnation points using artificial hair sensors

    Science.gov (United States)

    Phillips, D. M.; Ray, C. W.; Hagen, B. J.; Su, W.; Baur, J. W.; Reich, G. W.

    2015-11-01

    Recent interest in fly-by-feel approaches for aircraft control has motivated the development of novel sensors for use in aerial systems. Artificial hair sensors (AHSs) are one type of device that promise to fill a unique niche in the sensory suite for aerial systems. In this work, we investigate the capability of an AHS based on structural glass fibers to directly identify flow stagnation and separation points on a cylindrical domain in a steady flow. The glass fibers are functionalized with a radially aligned carbon nanotube (CNT) forest and elicit a piezoresistive response as the CNT forest impinges on electrodes in a micropore when the hair is deflected due to viscous drag forces. Particle image velocimetry is used to measure the flow field allowing for the resulting moment and force acting on the hair to be correlated with the electrical response. It is demonstrated that the AHS provides estimates for the locations of both the stagnation and separation in steady flow. From this, a simulation of a heading estimation is presented to demonstrate a potential application for hair sensors. These results motivate the construction of large arrays of hair sensors for imaging and resolving flow structures in real time.

  3. Application of analytical detection concepts to immunogenicity testing.

    Science.gov (United States)

    Klakamp, Scott L; Lu, Hong; Tabrizi, Mohammad; Funelas, Cherryl; Roskos, Lorin K; Coleman, David

    2007-11-01

    The cut point and detection limit of any immunogenicity assay are two of the most important quantities that define the adequacy of an assay for detecting anti-drug antibodies against therapeutic proteins. To date in the immunogenicity testing literature, only the type I (alpha) error (i.e., the false positive) rate of the assay has been considered for establishing cut points. The "sensitivity" of an immunogenicity assay is usually reported as the concentration of a monoclonal or polyclonal anti-drug antibody standard corresponding to the signal at the cut point. We propose that a more traditional and rigorous analytical chemistry definition of the detection capability be utilized wherein both type I and type II (beta, false negative) error rates are considered. Specifically, the Hubaux-Vos technique of calculating cut points and limits of detection from predication intervals on calibration curves is recommended as a statistically rigorous approach. The utility of using receiver-operator characteristic curves for managing the type I and II error rates of an immunogenicity assay is also presented. In addition, we illustrate how a soluble receptor, sMUC18, for the therapeutic mAb ABX-MA1 can result in false positives by Biacore methodology. This result suggests that immunogenicity confirmatory experiments must be carefully designed, preferably with a smaller type I and II error rate than in the primary screening if an acceptable limit of detection can be maintained. PMID:17922557

  4. Cosmic Muon Detection for Geophysical Applications

    Directory of Open Access Journals (Sweden)

    László Oláh

    2013-01-01

    Full Text Available A portable cosmic muon detector has been developed for environmental, geophysical, or industrial applications. The device is a tracking detector based on the Close Cathode Chamber, an MWPC-like technology, allowing operation in natural underground caves or artificial tunnels, far from laboratory conditions. The compact, low power consumption system with sensitive surface of 0.1 m2 measures the angular distribution of cosmic muons with a resolution of 10 mrad, allowing for a detailed mapping of the rock thickness above the muon detector. Demonstration of applicability of the muon telescope (REGARD Muontomograph for civil engineering and measurements in artificial underground tunnels or caverns are presented.

  5. Dynamic Social Community Detection and Its Applications

    OpenAIRE

    Nguyen, Nam P; Dinh, Thang N.; Shen, Yilin; Thai, My T.

    2014-01-01

    Community structure is one of the most commonly observed features of Online Social Networks (OSNs) in reality. The knowledge of this feature is of great advantage: it not only provides helpful insights into developing more efficient social-aware solutions but also promises a wide range of applications enabled by social and mobile networking, such as routing strategies in Mobile Ad Hoc Networks (MANETs) and worm containment in OSNs. Unfortunately, understanding this structure is very challengi...

  6. Optical methods for ultrasensitive detection and analysis: Techniques and applications

    International Nuclear Information System (INIS)

    This conference is organized under the following sessions: Surface sensitive/ionization techniques; Advanced concepts in laser applications; Subwavelength spatial resolution spectroscopy; High-sensitivity spectroscopies using photothermal and polarization effects; Sensitive biomolecular detection; Novel optical spectroscopies and methods in condensed phase detection; Ultrasensitive detector methods

  7. Astronomers Detect Powerful Bursting Radio Source Discovery Points to New Class of Astronomical Objects

    Science.gov (United States)

    2005-03-01

    Astronomers at Sweet Briar College and the Naval Research Laboratory (NRL) have detected a powerful new bursting radio source whose unique properties suggest the discovery of a new class of astronomical objects. The researchers have monitored the center of the Milky Way Galaxy for several years and reveal their findings in the March 3, 2005 edition of the journal, “Nature”. This radio image of the central region of the Milky Way Galaxy holds a new radio source, GCRT J1745-3009. The arrow points to an expanding ring of debris expelled by a supernova. CREDIT: N.E. Kassim et al., Naval Research Laboratory, NRAO/AUI/NSF Principal investigator, Dr. Scott Hyman, professor of physics at Sweet Briar College, said the discovery came after analyzing some additional observations from 2002 provided by researchers at Northwestern University. “"We hit the jackpot!” Hyman said referring to the observations. “An image of the Galactic center, made by collecting radio waves of about 1-meter in wavelength, revealed multiple bursts from the source during a seven-hour period from Sept. 30 to Oct. 1, 2002 — five bursts in fact, and repeating at remarkably constant intervals.” Hyman, four Sweet Briar students, and his NRL collaborators, Drs. Namir Kassim and Joseph Lazio, happened upon transient emission from two radio sources while studying the Galactic center in 1998. This prompted the team to propose an ongoing monitoring program using the National Science Foundation’s Very Large Array (VLA) radio telescope in New Mexico. The National Radio Astronomy Observatory, which operates the VLA, approved the program. The data collected, laid the groundwork for the detection of the new radio source. “Amazingly, even though the sky is known to be full of transient objects emitting at X- and gamma-ray wavelengths,” NRL astronomer Dr. Joseph Lazio pointed out, “very little has been done to look for radio bursts, which are often easier for astronomical objects to produce

  8. A Fixed Point Theorem for Set-Valued Mapping in Abstract Convex Space with Application

    Institute of Scientific and Technical Information of China (English)

    FAN Xiao Dong; XIANG Shu Wen

    2009-01-01

    A new fixed point theorem and the selection property for upper semi-continuous setvalued mappings in abstract convexity space are established. As their applications the existence of Nash equilibrium for n-person non-cooperative generalized games is proved.

  9. 78 FR 65010 - Submission for Review: SF-15 Application for 10-Point Veteran Preference

    Science.gov (United States)

    2013-10-30

    ... MANAGEMENT Submission for Review: SF-15 Application for 10-Point Veteran Preference AGENCY: Office of... Preference. The SF-15 is used by agencies, OPM examining offices, and agency appointing officials to adjudicate individuals' claims for veterans' preference in accordance with the Veterans' Preference Act...

  10. Focal Image Plane Detection Based on Central Coordinate Point Spectral Value in Off-Axis Digital Particle Holography

    Science.gov (United States)

    Qiu, Peizhen; Deng, Lijun; Lu, Wenhui

    2015-12-01

    A method to detect the focal image plane from a single off-axis digital particle hologram is proposed. This method utilizes the central coordinate point spectral value of the reconstructed particle image as focusing criterion to detect the focal image plane. It is found that the central coordinate point spectral values come into maximum when the reconstruction distance is equal to the actual distance that was used in experiment of hologram acquisition. Numerical simulations are given to validate the feasibility and effectiveness of the proposed method. The proposed method is a potential and better option for studying three dimensional particles by using digital holography.

  11. Detection and quantification of the age-related point mutation A189G in the human mitochondrial DNA.

    OpenAIRE

    Thèves, Catherine; Keyser-Tracqui, Christine; Crubézy, Eric; Pierre Salles, Jean; Ludes, Bertrand; Telmon, Norbert

    2006-01-01

    Mutation analysis in the mitochondrial DNA (mtDNA) control region is widely used in population genetic studies as well as in forensic medicine. Among the difficulties linked to the mtDNA analysis, one can find the detection of heteroplasmy, which can be inherited or somatic. Recently, age-related point mutation A189G was described in mtDNA and shown to accumulate with age in muscles. We carried out the detection of this 189 heteroplasmic point mutation using three technologies: automated DNA ...

  12. Strong terahertz field generation, detection, and application

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ki-Yong [Univ. of Maryland, College Park, MD (United States)

    2016-05-22

    This report describes the generation and detection of high-power, broadband terahertz (THz) radiation with using femtosecond terawatt (TW) laser systems. In particular, this focuses on two-color laser mixing in gases as a scalable THz source, addressing both microscopic and macroscopic effects governing its output THz yield and radiation profile. This also includes the characterization of extremely broad THz spectra extending from microwaves to infrared frequencies. Experimentally, my group has generated high-energy (tens of microjoule), intense (>8 MV/cm), and broadband (0.01~60 THz) THz radiation in two-color laser mixing in air. Such an intense THz field can be utilized to study THz-driven extremely nonlinear phenomena in a university laboratory.

  13. Models for assessing the spatial distribution of geodetic point patterns: application to geoid prediction quality

    Science.gov (United States)

    Hassouna, Raaed Mohamed Kamel

    2013-05-01

    In this study, some stochastic and deterministic models have been proposed for the assessment of the regularity and isotropy of geodetic point patterns. These models utilized realized point configurations within a rectangular window, leaning on stochastic geometry. As an illustrative example, the geographical extent of the Egyptian Territory was selected as a test window. The proposed models have agreed with the visual and qualitative characteristics of the investigated patterns. Also, it has been found that the stochastic and deterministic models for regularity and isotropy have very strong mutual correlation coefficients. Furthermore, the proposed models were applied to some geoid interpolation algorithms. In particular, the relationships among the data/check point distributions and the geoid interpolation accuracies, were investigated. Finally, a closed expression was proposed, which efficiently describes the relations among such features. So, it is recommended to use such approach for the pre-analysis and planning of the geographic distributions of point patterns in similar and other geodetic applications.

  14. Fixed Point Results for α-ψ-Contractive Mappings Including Almost Contractions and Applications

    Directory of Open Access Journals (Sweden)

    Gonca Durmaz

    2014-01-01

    Full Text Available In the recent paper (B. Samet, C. Vetro, and P. Vetro, Fixed point theorems for α-ψ-contractive type mappings, Nonlinear Analysis. Theory, Methods and Applications, 75 (2012, 2154-2165., the authors introduced the concept of α-admissible maps on metric spaces. Using this new concept, they presented some nice fixed point results. Also, they gave an existence theorem for integral equation to show the usability of their result. Then, many authors focused on this new concept and obtained a lot of fixed point results, which are used for existence theorems. In this paper, we not only extend some of the recent results about this direction but also generalize them. Then, we give some examples to show our results are proper extensions. Furthermore, we use our results to obtain the existence and uniqueness result for a solution of fourth order two-point boundary value problem.

  15. Fixed point theorems for mappings satisfying contractive conditions of integral type and applications

    Directory of Open Access Journals (Sweden)

    Kang Shin

    2011-01-01

    Full Text Available Abstract In this paper, the existence, uniqueness and iterative approximations of fixed points for contractive mappings of integral type in complete metric spaces are established. As applications, the existence, uniqueness and iterative approximations of solutions for a class of functional equations arising in dynamic programming are discussed. The results presented in this paper extend and improve essentially the results of Branciari (A fixed point theorem for mappings satisfying a general contractive condition of integral type. Int. J. Math. Math. Sci. 29, 531-536, 2002, Kannan (Some results on fixed points. Bull. Calcutta Math. Soc. 60, 71-76, 1968 and several known results. Four concrete examples involving the contractive mappings of integral type with uncountably many points are constructed. 2010 Mathematics Subject Classfication: 54H25, 47H10, 49L20, 49L99, 90C39

  16. DELPHI - fast and adaptive computational laser point detection and visual footprint quantification for arbitrary underwater image collections

    Directory of Open Access Journals (Sweden)

    Timm eSchoening

    2015-04-01

    Full Text Available Marine researchers continue to create large quantities of benthic images e.g. using AUVs (Autonomous Underwater Vehicles. In order to quantify the size of sessile objects in the images, a pixel-to-centimetre ratio is required for each image, often indirectly provided through a geometric laser point (LP pattern, projected onto the seafloor. Manual annotation of these LPs in all images is too time-consuming and thus infeasible for nowadays data volumes. Because of the technical evolution of camera rigs, the LP's geometrical layout and colour features vary for different expeditions and projects. This makes the application of one algorithm, tuned to a strictly defined LP pattern, also ineffective.Here we present the web-tool DELPHI, that efficiently learns the LP layout for one image transect / collection from just a small number of hand labelled LPs and applies this layout model to the rest of the data. The efficiency in adapting to new data allows to compute the LPs and the pixel-to-centimetre ratio fully automatic and with high accuracy. DELPHI is applied to two real-world examples and shows clear improvements regarding reduction of tuning effort for new LP patterns as well as increasing detection performance.

  17. DROIDSWAN: DETECTING MALICIOUS ANDROID APPLICATIONS BASED ON STATIC FEATURE ANALYSIS

    Directory of Open Access Journals (Sweden)

    Babu Rajesh V

    2015-07-01

    Full Text Available Android being a widely used mobile platform has witnessed an increase in the number of malicious samples on its market place. The availability of multiple sources for downloading applications has also contributed to users falling prey to malicious applications. Classification of an Android application as malicious or benign remains a challenge as malicious applications maneuver to pose themselves as benign. This paper presents an approach which extracts various features from Android Application Package file (APK using static analysis and subsequently classifies using machine learning techniques. The contribution of this work includes deriving, extracting and analyzing crucial features of Android applications that aid in efficient classification. The analysis is carried out using various machine learning algorithms with both weighted and non-weighted approaches. It was observed that weighted approach depicts higher detection rates using fewer features. Random Forest algorithm exhibited high detection rate and shows the least false positive rate.

  18. Analysis and application of the methods of halogen-containing substance detection in leak detection technique

    International Nuclear Information System (INIS)

    Gasoanalytical methods of halogen-containing substance detection, which are used or can be used for tightness control, are considered. Methods realized in modern leak detectors are mentioned, their specific features, drawbacks are pointed out. The importance of the tightness control automation is emphasized. The conclusion is made that the principle of halogen-containing substance detection, based on the effect of thermoionic emission current increase, is the most perspective

  19. Blind spot detection using vision for automotive applications

    Institute of Scientific and Technical Information of China (English)

    Miguel (A)ngel SOTELO; José BARRIGA

    2008-01-01

    This paper describes a vision-based system for blind spot detection (BSD) in intelligent vehicle applications. A camera is mounted in the lateral mirror of a car with the intention of visually detecting cars that are located in the so-called blind spot and cannot be perceived by the vehicle driver. The detection of cars in the blind spot is carried out using computer vision techniques,based on optical flow and a double-stage data clustering technique for robust vehicle detection.

  20. Two-Dimensional Change Detection Methods Remote Sensing Applications

    CERN Document Server

    Ilsever, Murat

    2012-01-01

    Change detection using remotely sensed images has many applications, such as urban monitoring, land-cover change analysis, and disaster management. This work investigates two-dimensional change detection methods. The existing methods in the literature are grouped into four categories: pixel-based, transformation-based, texture analysis-based, and structure-based. In addition to testing existing methods, four new change detection methods are introduced: fuzzy logic-based, shadow detection-based, local feature-based, and bipartite graph matching-based. The latter two methods form the basis for a

  1. Membrane-based, sedimentation-assisted plasma separator for point-of-care applications

    OpenAIRE

    Liu, Changchun; Mauk, Michael; Gross, Robert; Bushman, Frederic D.; Edelstein, Paul H.; Collman, Ronald G.; Bau, Haim H

    2013-01-01

    Often, high sensitivity, point of care, clinical tests, such as HIV viral load, require large volumes of plasma. Although centrifuges are ubiquitously used in clinical laboratories to separate plasma from whole blood, centrifugation is generally inappropriate for on-site testing. Suitable alternatives are not readily available to separate the relatively large volumes of plasma from milliliters of blood that may be needed to meet stringent limit-of-detection specifications for low abundance ta...

  2. Building Point Detection from Vehicle-Borne LiDAR Data Based on Voxel Group and Horizontal Hollow Analysis

    OpenAIRE

    Yu Wang; Liang Cheng; Yanming Chen; Yang Wu; Manchun Li

    2016-01-01

    Information extraction and three-dimensional (3D) reconstruction of buildings using the vehicle-borne laser scanning (VLS) system is significant for many applications. Extracting LiDAR points, from VLS, belonging to various types of building in large-scale complex urban environments still retains some problems. In this paper, a new technical framework for automatic and efficient building point extraction is proposed, including three main steps: (1) voxel group-based shape recognition; (2) cat...

  3. Applicability of a desiccant dew-point cooling system independent of external water sources

    DEFF Research Database (Denmark)

    Bellemo, Lorenzo; Elmegaard, Brian; Kærn, Martin;

    2015-01-01

    The applicability of a technical solution for making desiccant cooling systems independent of external water sources is investigated. Water is produced by condensing the desorbed water vapour in a closed regeneration circuit. Desorbed water recovery is applied to a desiccant dew-point cooling...... system, which includes a desiccant wheel and a dew point cooler. The system is simulated during the summer period in the Mediterranean climate of Rome and it results completely independent of external water sources. The seasonal thermal COP drops 8% in comparison to the open regeneration circuit solution...

  4. Toward the Optimal Configuration of Dynamic Voltage Scaling Points in Real-Time Applications

    Institute of Scientific and Technical Information of China (English)

    Hui-Zhan Yi; Xue-Jun Yang

    2006-01-01

    In real-time applications, compiler-directed dynamic voltage scaling (DVS) could reduce energy consumption efficiently, where compiler put voltage scaling points in the proper places, and the supply voltage and clock frequency were adjusted to the relationship between the reduced time and the reduced workload. This paper presents the optimal configuration of dynamic voltage scaling points without voltage scaling overhead, which minimizes energy consumption. The conclusion is proved theoretically. Finally, it is confirmed by simulations with equally-spaced voltage scaling configuration.

  5. The Homogeneous Interior-Point Algorithm: Nonsymmetric Cones, Warmstarting, and Applications

    DEFF Research Database (Denmark)

    Skajaa, Anders

    The overall topic of this thesis is convex conic optimization, a sub-field of mathematical optimization that attacks optimization problem with a certain geometric structure. These problems allow for modelling of an extremely wide range of real-world problems, but the availability of solution algo...... benchmarking problem test sets as well as an application from smart energy systems....... algorithms for these problems is still limited. The goal of this thesis is to investigate and shed light on two computational aspects of homogeneous interior-point algorithms for convex conic optimization: The first part studies the possibility of devising a homogeneous interior-point method aimed at solving...

  6. Point application with Angong Niuhuang sticker protects hippocampal and cortical neurons in rats with cerebral ischemia

    Directory of Open Access Journals (Sweden)

    Dong-shu Zhang

    2015-01-01

    Full Text Available Angong Niuhuang pill, a Chinese materia medica preparation, can improve neurological functions after acute ischemic stroke. Because of its inconvenient application and toxic components (Cinnabaris and Realgar, we used transdermal enhancers to deliver Angong Niuhuang pill by modern technology, which expanded the safe dose range and clinical indications. In this study, Angong Niuhuang stickers administered at different point application doses (1.35, 2.7, and 5.4 g/kg were administered to the Dazhui (DU14, Qihai (RN6 and Mingmen (DU4 of rats with chronic cerebral ischemia, for 4 weeks. The Morris water maze was used to determine the learning and memory ability of rats. Hematoxylin-eosin staining and Nissl staining were used to observe neuronal damage of the cortex and hippocampal CA1 region in rats with chronic cerebral ischemia. The middle- and high-dose point application of Angong Niuhuang stickers attenuated neuronal damage in the cortex and hippocampal CA1 region, and improved the memory of rats with chronic cerebral ischemia with an efficacy similar to interventions by electroacupuncture at Dazhui (DU14, Qihai (RN6 and Mingmen (DU4. Our experimental findings indicate that point application with Angong Niuhuang stickers can improve cognitive function after chronic cerebral ischemia in rats and is neuroprotective with an equivalent efficacy to acupuncture.

  7. Applicability of bacterial cellulose as an alternative to paper points in endodontic treatment.

    Science.gov (United States)

    Yoshino, Aya; Tabuchi, Mari; Uo, Motohiro; Tatsumi, Hiroto; Hideshima, Katsumi; Kondo, Seiji; Sekine, Joji

    2013-04-01

    Dental root canal treatment is required when dental caries progress to infection of the dental pulp. A major goal of this treatment is to provide complete decontamination of the dental root canal system. However, the morphology of dental root canal systems is complex, and many human dental roots have inaccessible areas. In addition, dental reinfection is fairly common. In conventional treatment, a cotton pellet and paper point made from plant cellulose is used to dry and sterilize the dental root canal. Such sterilization requires a treatment material with high absorbency to remove any residue, the ability to improve the efficacy of intracanal medication and high biocompatibility. Bacterial cellulose (BC) is produced by certain strains of bacteria. In this study, we developed BC in a pointed form and evaluated its applicability as a novel material for dental canal treatment with regard to solution absorption, expansion, tensile strength, drug release and biocompatibility. We found that BC has excellent material and biological characteristics compared with conventional materials, such as paper points (plant cellulose). BC showed noticeably higher absorption and expansion than paper points, and maintained a high tensile strength even when wet. The cumulative release of a model drug was significantly greater from BC than from paper points, and BC showed greater compatibility than paper points. Taken together, BC has great potential for use in dental root canal treatment. PMID:23268234

  8. Anomaly Detection Based on Sensor Data in Petroleum Industry Applications

    Directory of Open Access Journals (Sweden)

    Luis Martí

    2015-01-01

    Full Text Available Anomaly detection is the problem of finding patterns in data that do not conform to an a priori expected behavior. This is related to the problem in which some samples are distant, in terms of a given metric, from the rest of the dataset, where these anomalous samples are indicated as outliers. Anomaly detection has recently attracted the attention of the research community, because of its relevance in real-world applications, like intrusion detection, fraud detection, fault detection and system health monitoring, among many others. Anomalies themselves can have a positive or negative nature, depending on their context and interpretation. However, in either case, it is important for decision makers to be able to detect them in order to take appropriate actions. The petroleum industry is one of the application contexts where these problems are present. The correct detection of such types of unusual information empowers the decision maker with the capacity to act on the system in order to correctly avoid, correct or react to the situations associated with them. In that application context, heavy extraction machines for pumping and generation operations, like turbomachines, are intensively monitored by hundreds of sensors each that send measurements with a high frequency for damage prevention. In this paper, we propose a combination of yet another segmentation algorithm (YASA, a novel fast and high quality segmentation algorithm, with a one-class support vector machine approach for efficient anomaly detection in turbomachines. The proposal is meant for dealing with the aforementioned task and to cope with the lack of labeled training data. As a result, we perform a series of empirical studies comparing our approach to other methods applied to benchmark problems and a real-life application related to oil platform turbomachinery anomaly detection.

  9. Adaptive error detection for HDR/PDR brachytherapy: Guidance for decision making during real-time in vivo point dosimetry

    DEFF Research Database (Denmark)

    Kertzscher Schwencke, Gustavo Adolfo Vladimir; Andersen, Claus E.; Tanderup, Kari

    2014-01-01

    Purpose:This study presents an adaptive error detection algorithm (AEDA) for real-timein vivo point dosimetry during high dose rate (HDR) or pulsed dose rate (PDR) brachytherapy (BT) where the error identification, in contrast to existing approaches, does not depend on an a priori reconstruction of...... identify all false errors represented by mispositioned dosimeters contrary to an error detection algorithm relying on the original reconstruction. Conclusions:The study demonstrates that the AEDA error identification during HDR/PDR BT relies on a stable dosimeter position rather than on an accurate...... dosimeter reconstruction, and the AEDA’s capacity to distinguish between true and false error scenarios. The study further shows that the AEDA can offer guidance in decision making in the event of potential errors detected with real-time in vivo point dosimetry....

  10. Advanced Yellow Fever Virus Genome Detection in Point-of-Care Facilities and Reference Laboratories

    OpenAIRE

    Domingo, Cristina; Patel, Pranav; Yillah, Jasmin; Weidmann, Manfred; Méndez, Jairo A.; Nakouné, Emmanuel Rivalyn; Niedrig, Matthias

    2012-01-01

    Reported methods for the detection of the yellow fever viral genome are beset by limitations in sensitivity, specificity, strain detection spectra, and suitability to laboratories with simple infrastructure in areas of endemicity. We describe the development of two different approaches affording sensitive and specific detection of the yellow fever genome: a real-time reverse transcription-quantitative PCR (RT-qPCR) and an isothermal protocol employing the same primer-probe set but based on he...

  11. Full distributed fiber optical sensor for intrusion detection in application to buried pipelines

    Institute of Scientific and Technical Information of China (English)

    Jianzhong Gao; Zhuangde Jiang; Yulong Zhao; Li Zhu; Guoxian Zhao

    2005-01-01

    Based on the microbend effect of optical fiber, a distributed sensor for real-time continuous monitoring of intrusion in application to buried pipelines is proposed. The sensing element is a long cable with a special structure made up of an elastic polymer wire, an optical fiber, and a metal wire. The damage point is located with an embedded optical time domain reflectometry (OTDR) instrument. The intrusion types can be indicated by the amplitude of output voltage. Experimental results show that the detection system can alarm adequately under abnormal load and can locate the intrusion point within 22.4 m for distance of 3.023 km.

  12. Point Application of Medicated Cakes for Treatment of Asthma in Children—— A Report of 60 Cases

    Institute of Scientific and Technical Information of China (English)

    Lu Lisheng; Wang Mingming; Chen Huili

    2006-01-01

    Objective:To evaluate the therapeutic effects of point application of medicated cakes for prevention and treatment of recurrent asthma in children.Methods:Point application of medicated cakes was performed in 60 asthmatic children at the remission stage,with its effect compared with that of ketotifen used in the control group of 30 cases.Results:With a total effective rate of 85%,the point application of medicated cakes was found to be superior to that of the control group(P<0.05).Conclusion:Point application of medicated cakes is a simple,effective and safe therapy for asthmatic children.

  13. Interior Point Methods on GPU with application to Model Predictive Control

    DEFF Research Database (Denmark)

    Gade-Nielsen, Nicolai Fog

    The goal of this thesis is to investigate the application of interior point methods to solve dynamical optimization problems, using a graphical processing unit (GPU) with a focus on problems arising in Model Predictice Control (MPC). Multi-core processors have been available for over ten years now......, and demonstrate that our implementation can reduce the solution time substantially. There are multiple software packages available for solving optimization problems with interior point methods, such as GLPK, IPOPT, MOSEK and many more. However, none of these support the GPU yet. With this thesis, we include a new...... software package called GPUOPT, available under the non-restrictive MIT license. GPUOPT includes includes a primal-dual interior-point method, which supports both the CPU and the GPU. It is implemented as multiple components, where the matrix operations and solver for the Newton directions is separated...

  14. HESSIAN MATRIX BASED SADDLE POINT DETECTION FOR GRANULES SEGMENTALTION IN 2D IMAGE

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Segmenting the touching objects in an image has been remaining as a hot subject due to the problematic complexities,and a vast number of algorithms designed to tackle this issue have come into being since a decade ago.In this paper,a new granule segmentation algorithm is developed using saddle point as the cutting point.The image is binarized and then sequentially eroded to form a gray-scale topographic counterpart,followed by using Hessian matrix computation to search for the saddle point. The segmentation is performed by cutting through the saddle point and along the maximal gradient path on the topographic surface.The results of the algorithm test on the given real images indicate certain superiorities in both the segmenting robustness and execution time to the referenced methods.

  15. Target Detection: Remote Sensing Techniques for Defence Applications

    Directory of Open Access Journals (Sweden)

    B. B. Chaudhuri

    1995-10-01

    Full Text Available The tremendous development in remote sensing technology in the recent past has opened up new challenges in defence applications. On important area of such applications is in target detection. This paper describes both classical and newly developed approaches to detect the targets by using remotely-sensed digital images. The classical approach includes statistical classification methods and image processing techniques. The new approach deals with a relatively new sensor technology, namely, synthetic aperture radar (SAR systems and fast developing tools, like neural networks and multisource data integration for analysis and interpretation. With SAR images, it is possible to detect targets or features of a target that is otherwise not possible. Neural networks and multisource data integration tools also have a great potential in analysing and interpreting remote sensing data for target detection.

  16. Tree Species Detection Accuracies Using Discrete Point Lidar and Airborne Waveform Lidar

    OpenAIRE

    Turnblom, Eric C.; L. Monika Moskal; Vaughn, Nicholas R.

    2012-01-01

    Species information is a key component of any forest inventory. However, when performing forest inventory from aerial scanning Lidar data, species classification can be very difficult. We investigated changes in classification accuracy while identifying five individual tree species (Douglas-fir, western redcedar, bigleaf maple, red alder, and black cottonwood) in the Pacific Northwest United States using two data sets: discrete point Lidar data alone and discrete point data in combination wit...

  17. Building Point Detection from Vehicle-Borne LiDAR Data Based on Voxel Group and Horizontal Hollow Analysis

    Directory of Open Access Journals (Sweden)

    Yu Wang

    2016-05-01

    Full Text Available Information extraction and three-dimensional (3D reconstruction of buildings using the vehicle-borne laser scanning (VLS system is significant for many applications. Extracting LiDAR points, from VLS, belonging to various types of building in large-scale complex urban environments still retains some problems. In this paper, a new technical framework for automatic and efficient building point extraction is proposed, including three main steps: (1 voxel group-based shape recognition; (2 category-oriented merging; and (3 building point identification by horizontal hollow ratio analysis. This article proposes a concept of “voxel group” based on the voxelization of VLS points: each voxel group is composed of several voxels that belong to one single real-world object. Then the shapes of point clouds in each voxel group are recognized and this shape information is utilized to merge voxel group. This article puts forward a characteristic nature of vehicle-borne LiDAR building points, called “horizontal hollow ratio”, for efficient extraction. Experiments are analyzed from two aspects: (1 building-based evaluation for overall experimental area; and (2 point-based evaluation for individual building using the completeness and correctness. The experimental results indicate that the proposed framework is effective for the extraction of LiDAR points belonging to various types of buildings in large-scale complex urban environments.

  18. Individual tree detection based on densities of high points of high resolution airborne lidar

    NARCIS (Netherlands)

    Abd Rahman, M.Z.; Gorte, B.G.H.

    2008-01-01

    The retrieval of individual tree location from Airborne LiDAR has focused largely on utilizing canopy height. However, high resolution Airborne LiDAR offers another source of information for tree detection. This paper presents a new method for tree detection based on high points’ densities from a hi

  19. Submodule Integrated Distributed Maximum Power Point Tracking for Solar Photovoltaic Applications

    OpenAIRE

    Pilawa-Podgurski, Robert C. N.; Perreault, David J.

    2012-01-01

    This paper explores the benefits of distributed power electronics in solar photovoltaic applications through the use of submodule integrated maximum power point trackers (MPPT). We propose a system architecture that provides a substantial increase in captured energy during partial shading conditions, while at the same time enabling significant overall cost reductions. This is achieved through direct integration of miniature MPPT power converters into existing junction boxes. We describe the d...

  20. ELXED POINT THEOREM OF COMPOSITION g-CONTRACTION MAPPING AND ITS APPLICATIONS

    Institute of Scientific and Technical Information of China (English)

    云天铨

    2001-01-01

    Any composition sequential mapping, periodic composition mapping of a complete non-empty metric space M into M with geometric mean contraction ratio less than 1 ( simplifying as "g-contraction mapping" ) has a unique fixed point in M . Applications of the theorem to the proof of existence and uniqueness of the solutions of a set of non-linear differential equations and a coupled integral equations of symmetric bending of shallow shell of revolution are given.

  1. Fixed point theorems for M-contraction type maps in partially ordered metric spaces and applications

    OpenAIRE

    Sachin V. Bedre; S.M. Khairnar; Desale, B. S.

    2014-01-01

    This paper presents hybrid fixed point theorems of Krasnosel’skii type and some nonlinear alternatives of Leray-Schauder type involving sums of two operators in a partially ordered normed linear spaces. The results are applied to functional integral equations that have been considered in Ntouyas and Tsamatos[21] for proving the existence of solutions under certain monotonic conditions blending with the existence of upper or lower solution. Applications are alsogiven to some nonlinear function...

  2. Web Application Security by SQL Injection DetectionTools

    OpenAIRE

    Atefeh Tajpour; Suhaimi Ibrahim; Mohammad Sharifi

    2012-01-01

    SQL injection is a type of attack which the attacker adds Structured Query Language code to a web form input box to gain access or make changes to data. SQL injection vulnerability allows an attacker to flow commands directly to a web application underlying database and destroy functionality or confidentiality. Researchers have proposed different tools to detect and prevent this vulnerability. In this paper we present all SQL injection attack types and also current tools which can detect or p...

  3. A 3D clustering approach for point clouds to detect and quantify changes at a rock glacier front

    Science.gov (United States)

    Micheletti, Natan; Tonini, Marj; Lane, Stuart N.

    2016-04-01

    Terrestrial Laser Scanners (TLS) are extensively used in geomorphology to remotely-sense landforms and surfaces of any type and to derive digital elevation models (DEMs). Modern devices are able to collect many millions of points, so that working on the resulting dataset is often troublesome in terms of computational efforts. Indeed, it is not unusual that raw point clouds are filtered prior to DEM creation, so that only a subset of points is retained and the interpolation process becomes less of a burden. Whilst this procedure is in many cases necessary, it implicates a considerable loss of valuable information. First, and even without eliminating points, the common interpolation of points to a regular grid causes a loss of potentially useful detail. Second, it inevitably causes the transition from 3D information to only 2.5D data where each (x,y) pair must have a unique z-value. Vector-based DEMs (e.g. triangulated irregular networks) partially mitigate these issues, but still require a set of parameters to be set and a considerable burden in terms of calculation and storage. Because of the reasons above, being able to perform geomorphological research directly on point clouds would be profitable. Here, we propose an approach to identify erosion and deposition patterns on a very active rock glacier front in the Swiss Alps to monitor sediment dynamics. The general aim is to set up a semiautomatic method to isolate mass movements using 3D-feature identification directly from LiDAR data. An ultra-long range LiDAR RIEGL VZ-6000 scanner was employed to acquire point clouds during three consecutive summers. In order to isolate single clusters of erosion and deposition we applied the Density-Based Scan Algorithm with Noise (DBSCAN), previously successfully employed by Tonini and Abellan (2014) in a similar case for rockfall detection. DBSCAN requires two input parameters, strongly influencing the number, shape and size of the detected clusters: the minimum number of

  4. Solid state nuclear track detection principles, methods and applications

    CERN Document Server

    Durrani, S A; ter Haar, D

    1987-01-01

    Solid State Nuclear Track Detection: Principles, Methods and Applications is the second book written by the authors after Nuclear Tracks in Solids: Principles and Applications. The book is meant as an introduction to the subject solid state of nuclear track detection. The text covers the interactions of charged particles with matter; the nature of the charged-particle track; the methodology and geometry of track etching; thermal fading of latent damage trails on tracks; the use of dielectric track recorders in particle identification; radiation dossimetry; and solid state nuclear track detecti

  5. 77 FR 16278 - License Renewal Application for Indian Point Nuclear Generating Units 2 and 3; Entergy Nuclear...

    Science.gov (United States)

    2012-03-20

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION License Renewal Application for Indian Point Nuclear Generating Units 2 and 3; Entergy Nuclear Operations, Inc. AGENCY: Nuclear Regulatory Commission. ACTION: License renewal application; intent...

  6. Road Signs Detection and Recognition Utilizing Images and 3d Point Cloud Acquired by Mobile Mapping System

    Science.gov (United States)

    Li, Y. H.; Shinohara, T.; Satoh, T.; Tachibana, K.

    2016-06-01

    High-definition and highly accurate road maps are necessary for the realization of automated driving, and road signs are among the most important element in the road map. Therefore, a technique is necessary which can acquire information about all kinds of road signs automatically and efficiently. Due to the continuous technical advancement of Mobile Mapping System (MMS), it has become possible to acquire large number of images and 3d point cloud efficiently with highly precise position information. In this paper, we present an automatic road sign detection and recognition approach utilizing both images and 3D point cloud acquired by MMS. The proposed approach consists of three stages: 1) detection of road signs from images based on their color and shape features using object based image analysis method, 2) filtering out of over detected candidates utilizing size and position information estimated from 3D point cloud, region of candidates and camera information, and 3) road sign recognition using template matching method after shape normalization. The effectiveness of proposed approach was evaluated by testing dataset, acquired from more than 180 km of different types of roads in Japan. The results show a very high success in detection and recognition of road signs, even under the challenging conditions such as discoloration, deformation and in spite of partial occlusions.

  7. Trend analysis and change point detection of annual and seasonal precipitation and temperature series over southwest Iran

    Indian Academy of Sciences (India)

    Mohammad Zarenistanak; Amit G Dhorde; R H Kripalani

    2014-03-01

    This paper presents results of trend analysis and change point detection of annual and seasonal precipitation, and mean temperature (TM), maximum temperature (TMAX) and minimum temperature (TMIN) time series of the period 1950–2007. Investigations were carried out for 50 precipitation stations and 39 temperature stations located in southwest Iran. Three statistical tests including Pettitt’s test, Sequential Mann–Kendall test (SQ-MK test) and Mann–Kendall rank test (MK-test) were used for the analysis. The results obtained for precipitation series indicated that most stations showed insignificant trends in annual and seasonal series. Out of the stations which showed significant trends, highest numbers were observed during winter season while no significant trends were detected in summer precipitation. Moreover, no decreasing significant trends were detected by statistical tests in annual and seasonal precipitation series. The analysis of temperature trends revealed a significant increase during summer and spring seasons. TMAX was more stable than TMIN and TM, and winter was stable compared to summer, spring and autumn seasons. The results of change point detection indicated that most of the positive significant mutation points in TM, TMAX and TMIN began in the 1990s.

  8. Detection of K-ras point mutation and telomerase activity during endoscopic retrograde cholangiopancreatography in diagnosis of pancreatic cancer

    Institute of Scientific and Technical Information of China (English)

    Guo-Xiong Zhou; Jie-Fei Huang; Zhao-Shen Li; Guo-Ming Xu; Feng Liu; Hong Zhang

    2004-01-01

    AIM: To study the value of monitoring K-ras point mutation at codon 12 and telomerase activity in exfoliated cells obtained from pancreatic duct brushings during endoscopic retrograde cholangiopancreatography (ERCP) in the diagnosis of pancreatic cancer.METHODS: Exfoliated cells obtained from pancreatic duct brushings during ERCP were examined in 27 patients: 23with pancreatic cancers, 4 with chronic pancreatitis. K-fas point mutation was detected with the polymerase chain reaction and restriction fragment-length polymorphism (PCR-RFLP). Telomerase activity was detected by PCR and telomeric repeat amplification protocol assay (PCR-TRAPELISA).RESULTS: The telomerase activities in 27 patients were measured in 21 exfoliated cell samples obtained from pancreatic duct brushings. D450 value of telomerase activities in pancreatic cancer and chronic pancreatitis were 0.446±0.27and 0.041±0.0111, respectively. Seventy-seven point eight percent (14/18) of patients with pancreatic cancer and none of the patients with chronic pancreatitis showed telomerase activity in cells collected from pancreatic duct brushings when cutoff value of telomerase activity was set at 2.0. The K-ras gene mutation rate (72.2%) in pancreatic cancer was higher than that in chronic pancreatitis (33.3%)(P<0.05). In considering of both telomerase activities and K-ras point mutation, the total positive rate was 83.3%(15/18), and the specificity was 100%.CONCLUSION: Changes of telomerase activities and K-ras point mutation at codon 12 may be an early event of malignant progression in pancreatic cancer. Detection of telomerase activity and K-ras point mutation at codon 12may be complementary to each other, and is useful in diagnosis of pancreatic cancer.

  9. Archival Legacy Investigations of Circumstellar Environments (ALICE): Statistical assessment of point source detections

    Science.gov (United States)

    Choquet, Élodie; Pueyo, Laurent; Soummer, Rémi; Perrin, Marshall D.; Hagan, J. Brendan; Gofas-Salas, Elena; Rajan, Abhijith; Aguilar, Jonathan

    2015-09-01

    The ALICE program, for Archival Legacy Investigation of Circumstellar Environment, is currently conducting a virtual survey of about 400 stars, by re-analyzing the HST-NICMOS coronagraphic archive with advanced post-processing techniques. We present here the strategy that we adopted to identify detections and potential candidates for follow-up observations, and we give a preliminary overview of our detections. We present a statistical analysis conducted to evaluate the confidence level on these detection and the completeness of our candidate search.

  10. Archival Legacy Investigations of Circumstellar Environments (ALICE): Statistical assessment of point source detections

    CERN Document Server

    Choquet, É; Soummer, R; Perrin, M D; Hagan, J B; Gofas-Salas, E; Rajan, A; Aguilar, J

    2015-01-01

    The ALICE program, for Archival Legacy Investigation of Circumstellar Environment, is currently conducting a virtual survey of about 400 stars, by re-analyzing the HST-NICMOS coronagraphic archive with advanced post-processing techniques. We present here the strategy that we adopted to identify detections and potential candidates for follow-up observations, and we give a preliminary overview of our detections. We present a statistical analysis conducted to evaluate the confidence level on these detection and the completeness of our candidate search.

  11. Improving Web Application Firewalls to detect advanced SQL injection attacks

    OpenAIRE

    Makiou, Abdelhamid; Begriche, Youcef; Serhrouchni, Ahmed

    2014-01-01

    Injections flaws which include SQL injection are the most prevalent security threats affecting Web applications[1]. To mitigate these attacks, Web Application Firewalls (WAFs) apply security rules in order to both inspect HTTP data streams and detect malicious HTTP transactions. Nevertheless, attackers can bypass WAF's rules by using sophisticated SQL injection techniques. In this paper, we introduce a novel approach to dissect the HTTP traffic and inspect complex SQL injection attacks. Our m...

  12. P-Wave Onset Point Detection for Seismic Signal Using Bhattacharyya Distance

    OpenAIRE

    Bikash Chandra sahana

    2015-01-01

    In seismology Primary p-wave arrival identification is a fundamental problem for the geologist worldwide. Several numbers of algorithms that deal with p-wave onset detection and identification have already been proposed. Accurate p- wave picking is required for earthquake early warning system and determination of epicenter location etc. In this paper we have proposed a novel algorithm for p-wave detection using Bhattacharyya distance for seismic signals. In our study we have taken 50 numbers ...

  13. Smoothed extreme value estimators of non-uniform point processes boundaries with application to star-shaped supports estimation

    OpenAIRE

    Girard, Stéphane; Menneteau, Ludovic

    2011-01-01

    We address the problem of estimating the edge of a bounded set in R^d given a random set of points drawn from the interior. Our method is based on a transformation of estimators dedicated to uniform point processes and obtained by smoothing some of its bias corrected extreme points. An application to the estimation of star-shaped supports is presented.

  14. Bayesian multivariate linear regression with application to change point models in hydrometeorological variables

    Science.gov (United States)

    Seidou, O.; Asselin, J. J.; Ouarda, T. B. M. J.

    2007-08-01

    Multivariate linear regression is one of the most popular modeling tools in hydrology and climate sciences for explaining the link between key variables. Piecewise linear regression is not always appropriate since the relationship may experiment sudden changes due to climatic, environmental, or anthropogenic perturbations. To address this issue, a practical and general approach to the Bayesian analysis of the multivariate regression model is presented. The approach allows simultaneous single change point detection in a multivariate sample and can account for missing data in the response variables and/or in the explicative variables. It also improves on recently published change point detection methodologies by allowing a more flexible and thus more realistic prior specification for the existence of a change and the date of change as well as for the regression parameters. The estimation of all unknown parameters is achieved by Monte Carlo Markov chain simulations. It is shown that the developed approach is able to reproduce the results of Rasmussen (2001) as well as those of Perreault et al. (2000a, 2000b). Furthermore, two of the examples provided in the paper show that the proposed methodology can readily be applied to some problems that cannot be addressed by any of the above-mentioned approaches because of limiting model structure and/or restrictive prior assumptions. The first of these examples deals with single change point detection in the multivariate linear relationship between mean basin-scale precipitation at different periods of the year and the summer-autumn flood peaks of the Broadback River located in northern Quebec, Canada. The second one addresses the problem of missing data estimation with uncertainty assessment in multisite streamflow records with a possible simultaneous shift in mean streamflow values that occurred at an unknown date.

  15. Coherent demodulation of microwave signals by using optical heterodyne technique with applications to point to point indoor wireless communications systems

    Energy Technology Data Exchange (ETDEWEB)

    Garcia-Juarez, A; Gomez-Colin, M R; Rojas-Hernandez, A G [Universidad de Sonora (Mexico); Zaldivar-Huerta, I E; Aguayo-Rodriguez, G [Instituto Nacional de Astrofisica, Optica y Electronica (Mexico); Rodriguez-Asomoza, J, E-mail: agarcia@cifus.uson.mx [Universidad de las Americas-Puebla (Mexico)

    2011-01-01

    An optical communications system using a couple microstrip antennas for distributing point to point analog TV with coherent demodulation based on optical heterodyne in close vicinity is reported in this paper. In the proposed experimental setup, two optical waves at different wavelengths are mixed and applied to a photodetector. Then a beat signal with a frequency equivalent to the spacing of the two wavelengths is obtained at the output of the photodetector. This signal corresponds to a microwave signal located at 1.25 GHz, which it is used as a microwave carrier in the transmitter and as a local oscillator in the receiver of our optical communication system. The feasibility of this technique is demonstrated transmitting a TV signal of 66-72 MHz.

  16. Coherent demodulation of microwave signals by using optical heterodyne technique with applications to point to point indoor wireless communications systems

    International Nuclear Information System (INIS)

    An optical communications system using a couple microstrip antennas for distributing point to point analog TV with coherent demodulation based on optical heterodyne in close vicinity is reported in this paper. In the proposed experimental setup, two optical waves at different wavelengths are mixed and applied to a photodetector. Then a beat signal with a frequency equivalent to the spacing of the two wavelengths is obtained at the output of the photodetector. This signal corresponds to a microwave signal located at 1.25 GHz, which it is used as a microwave carrier in the transmitter and as a local oscillator in the receiver of our optical communication system. The feasibility of this technique is demonstrated transmitting a TV signal of 66-72 MHz.

  17. THE CLINICAL APPLICATIONS FOR AUTOMATIC DETECTION OF EXUDATES

    Directory of Open Access Journals (Sweden)

    K. Wisaeng

    2014-01-01

    Full Text Available Nowadays, the retinal imaging technology has been widely used for segmenting and detecting the exudates in diabetic retinopathy patients. Unfortunately, the retinal images in Thailand are poor-quality images. Therefore, detecting of exudates in a large number by screening programs, are very expensive in professional time and may cause human error. In this study, the clinical applications for detection of exudates from the poor quality retinal image are presented. An application incorporating function, including retinal color normalization, contrast enhancement, noise removal, color space selection and removal of the optic disc, was also designed to standardize the workflow of retinal analysis. Afterward, detection of exudate based on optimal global thresholding and improved adaptive Otsu’s algorithm was applied. Two experiments were conducted to validate the detection performance with local databases and a publicly available DIARETDB1 database. The first experiment showed the average sensitivity, specificity and accuracy of 93.8, 95.3 and 94.9%, respectively. The cross validation results of the second experiment, 60% (53 of the retinal images were used for training and 40% (36 for testing, the sensitivity, specificity and accuracy are 84.2, 85.9 and 85.2%, respectively. This result indicates the proposed clinical application provides an effective tool in the screening of exudates.

  18. Note on Studying Change Point of LRD Traffic Based on Li's Detection of DDoS Flood Attacking

    Directory of Open Access Journals (Sweden)

    Zhengmin Xia

    2010-01-01

    Full Text Available Distributed denial-of-service (DDoS flood attacks remain great threats to the Internet. To ensure network usability and reliability, accurate detection of these attacks is critical. Based on Li's work on DDoS flood attack detection, we propose a DDoS detection method by monitoring the Hurst variation of long-range dependant traffic. Specifically, we use an autoregressive system to estimate the Hurst parameter of normal traffic. If the actual Hurst parameter varies significantly from the estimation, we assume that DDoS attack happens. Meanwhile, we propose two methods to determine the change point of Hurst parameter that indicates the occurrence of DDoS attacks. The detection rate associated with one method and false alarm rate for the other method are also derived. The test results on DARPA intrusion detection evaluation data show that the proposed approaches can achieve better detection performance than some well-known self-similarity-based detection methods.

  19. LWIR hyperspectral imaging application and detection of chemical precursors

    Science.gov (United States)

    Lavoie, Hugo; Thériault, Jean-Marc; Bouffard, François; Puckrin, Eldon; Dubé, Denis

    2012-10-01

    Detection and identification of Toxic industrial chemicals (TICs) represent a major challenge to protect and sustain first responder and public security. In this context, passive Hyperspectral Imaging (HSI) is a promising technology for the standoff detection and identification of chemical vapors emanating from a distant location. To investigate this method, the Department of National Defense and Public Safety Canada have mandated Defense Research and Development Canada (DRDC) - Valcartier to develop and test Very Long Wave Infrared (VLWIR) HSI sensors for standoff detection. The initial effort was focused to address the standoff detection and identification of toxic industrial chemicals (TICs), surrogates and precursors. Sensors such as the Improved Compact ATmospheric Sounding Interferometer (iCATSI) and the Multi-option Differential Detection and Imaging Fourier Spectrometer (MoDDIFS) were developed for this application. This paper presents the sensor developments and preliminary results of standoff detection and identification of TICs and precursors. The iCATSI and MoDDIFS sensors are based on the optical differential Fourier-transform infrared (FTIR) radiometric technology and are able to detect, spectrally resolve and identify small leak at ranges in excess of 1 km. Results from a series of trials in asymmetric threat type scenarios are reported. These results serve to establish the potential of passive standoff HSI detection of TICs, precursors and surrogates.

  20. Probabilistic pipe fracture evaluations for leak-rate-detection applications

    International Nuclear Information System (INIS)

    Regulatory Guide 1.45, open-quotes Reactor Coolant Pressure Boundary Leakage Detection Systems,close quotes was published by the U.S. Nuclear Regulatory Commission (NRC) in May 1973, and provides guidance on leak detection methods and system requirements for Light Water Reactors. Additionally, leak detection limits are specified in plant Technical Specifications and are different for Boiling Water Reactors (BWRs) and Pressurized Water Reactors (PWRs). These leak detection limits are also used in leak-before-break evaluations performed in accordance with Draft Standard Review Plan, Section 3.6.3, open-quotes Leak Before Break Evaluation Proceduresclose quotes where a margin of 10 on the leak detection limit is used in determining the crack size considered in subsequent fracture analyses. This study was requested by the NRC to: (1) evaluate the conditional failure probability for BWR and PWR piping for pipes that were leaking at the allowable leak detection limit, and (2) evaluate the margin of 10 to determine if it was unnecessarily large. A probabilistic approach was undertaken to conduct fracture evaluations of circumferentially cracked pipes for leak-rate-detection applications. Sixteen nuclear piping systems in BWR and PWR plants were analyzed to evaluate conditional failure probability and effects of crack-morphology variability on the current margins used in leak rate detection for leak-before-break

  1. Probabilistic pipe fracture evaluations for leak-rate-detection applications

    Energy Technology Data Exchange (ETDEWEB)

    Rahman, S.; Ghadiali, N.; Paul, D.; Wilkowski, G. [Battelle, Columbus, OH (United States)

    1995-04-01

    Regulatory Guide 1.45, {open_quotes}Reactor Coolant Pressure Boundary Leakage Detection Systems,{close_quotes} was published by the U.S. Nuclear Regulatory Commission (NRC) in May 1973, and provides guidance on leak detection methods and system requirements for Light Water Reactors. Additionally, leak detection limits are specified in plant Technical Specifications and are different for Boiling Water Reactors (BWRs) and Pressurized Water Reactors (PWRs). These leak detection limits are also used in leak-before-break evaluations performed in accordance with Draft Standard Review Plan, Section 3.6.3, {open_quotes}Leak Before Break Evaluation Procedures{close_quotes} where a margin of 10 on the leak detection limit is used in determining the crack size considered in subsequent fracture analyses. This study was requested by the NRC to: (1) evaluate the conditional failure probability for BWR and PWR piping for pipes that were leaking at the allowable leak detection limit, and (2) evaluate the margin of 10 to determine if it was unnecessarily large. A probabilistic approach was undertaken to conduct fracture evaluations of circumferentially cracked pipes for leak-rate-detection applications. Sixteen nuclear piping systems in BWR and PWR plants were analyzed to evaluate conditional failure probability and effects of crack-morphology variability on the current margins used in leak rate detection for leak-before-break.

  2. Osmotic actuation for microfluidic components in point-of-care applications

    KAUST Repository

    Chen, Yu-Chih

    2013-01-01

    We present a novel design of micropumps and valves driven by osmotic force for point-of-care applications. Although there have been significant progresses in microfluidic components and control devices such as fluidic diodes, switches, resonators and digital-to-analog converters, the ultimate power source still depends on bulky off-chip components, which are expensive and cannot be easily miniaturized. For point-of-care applications, it is critical to integrate all the components in a compact size at low cost. In this work, we report two key active components actuated by osmotic mechanism for total integrated microfluidic system. For the proof of concept, we have demonstrated valve actuation, which can maintain stable ON/OFF switching operations under 125 kPa back pressure. We have also implemented an osmotic pump, which can pump a high flow rate over 30 μL/min for longer than 30 minutes. The experimental data demonstrates the possibility and potential of applying osmotic actuation in point-of-care disposable microfluidics. © 2013 IEEE.

  3. Accurate Point-of-Care Detection of Ruptured Fetal Membranes: Improved Diagnostic Performance Characteristics with a Monoclonal/Polyclonal Immunoassay

    OpenAIRE

    Rogers, Linda C.; Scott, Laurie; Block, Jon E

    2016-01-01

    OBJECTIVE Accurate and timely diagnosis of rupture of membranes (ROM) is imperative to allow for gestational age-specific interventions. This study compared the diagnostic performance characteristics between two methods used for the detection of ROM as measured in the same patient. METHODS Vaginal secretions were evaluated using the conventional fern test as well as a point-of-care monoclonal/polyclonal immunoassay test (ROM Plus®) in 75 pregnant patients who presented to labor and delivery w...

  4. Visual and colorimetric detection of Hg(2+) by cloud point extraction with functionalized gold nanoparticles as a probe.

    Science.gov (United States)

    Tan, Zhi-qiang; Liu, Jing-fu; Liu, Rui; Yin, Yong-guang; Jiang, Gui-bin

    2009-12-01

    Association with Hg(2+) enhances the hydrophobicity and triggers the cloud point extraction of approximately 4 nm-diameter gold nanoparticle probes functionalized with mercaptopropionic acid and homocystine, which results in the color change of the TX-114-rich phase from colorless to red, and therefore provides a novel approach for visual and colorimetric detection of Hg(2+) with ultrahigh sensitivity and selectivity. PMID:19904384

  5. Detecting groundwater discharge dynamics from point to catchment scale in a lowland stream: combining hydraulic and tracer methods

    OpenAIRE

    Poulsen, J B; Sebok, E.; Duque, C; Tetzlaff, D.; P. K. Engesgaard

    2014-01-01

    Detecting, quantifying, and understanding groundwater discharge to streams are crucial for the assessment of water, nutrient and contaminant exchange at the surface water–groundwater interface. In lowland agricultural catchments with significant groundwater discharge this is of particular importance because of the risk of excess leaching of nutrients to streams. Here we aim to combine hydraulic and tracer methods from point to catchment scale to assess the ...

  6. Detecting groundwater discharge dynamics from point-to-catchment scale in a lowland stream: combining hydraulic and tracer methods

    OpenAIRE

    Poulsen, J. R.; Sebok, E.; Duque, C; Tetzlaff, D.; P. K. Engesgaard

    2015-01-01

    Detecting, quantifying and understanding groundwater discharge to streams are crucial for the assessment of water, nutrient and contaminant exchange at the groundwater–surface water interface. In lowland agricultural catchments with significant groundwater discharge this is of particular importance because of the risk of excess leaching of nutrients to streams. Here we aim to combine hydraulic and tracer methods from point-to-catchment scale to assess the temporal and spatia...

  7. Application of biomarkers in cancer risk management: evaluation from stochastic clonal evolutionary and dynamic system optimization points of view.

    Directory of Open Access Journals (Sweden)

    Xiaohong Li

    2011-02-01

    Full Text Available Aside from primary prevention, early detection remains the most effective way to decrease mortality associated with the majority of solid cancers. Previous cancer screening models are largely based on classification of at-risk populations into three conceptually defined groups (normal, cancer without symptoms, and cancer with symptoms. Unfortunately, this approach has achieved limited successes in reducing cancer mortality. With advances in molecular biology and genomic technologies, many candidate somatic genetic and epigenetic "biomarkers" have been identified as potential predictors of cancer risk. However, none have yet been validated as robust predictors of progression to cancer or shown to reduce cancer mortality. In this Perspective, we first define the necessary and sufficient conditions for precise prediction of future cancer development and early cancer detection within a simple physical model framework. We then evaluate cancer risk prediction and early detection from a dynamic clonal evolution point of view, examining the implications of dynamic clonal evolution of biomarkers and the application of clonal evolution for cancer risk management in clinical practice. Finally, we propose a framework to guide future collaborative research between mathematical modelers and biomarker researchers to design studies to investigate and model dynamic clonal evolution. This approach will allow optimization of available resources for cancer control and intervention timing based on molecular biomarkers in predicting cancer among various risk subsets that dynamically evolve over time.

  8. Detection of Aberrant Data Points for an effective Effort Estimation using an Enhanced Algorithm with Adaptive Features

    Directory of Open Access Journals (Sweden)

    S. Sridhar

    2012-01-01

    Full Text Available Problem statement: The spiraling growth of IT industry has witnessed an unprecedented change in the software development paradigm, from algorithmic models to machine learning techniques. At present, there are no standard methods to predict the accuracy of software cost estimation, which is an important goal of the software community. Approach: This study proposes a simple and systematic algorithmic procedure for analogy based software cost prediction to detect the aberrant data points. The algorithm is analyzed and correlated with the Desharnais and NASA datasets containing all adaptive features with numerical and categorical variables. Results: The interpreted curves using the above datasets depict a discernible anomaly for the dataset having more categorical variables, thereby indicating the erroneous data points. Conclusion: The elimination of aberrant data points using the new algorithmic method improves the accuracy of software cost estimation using historical data sets.

  9. Electronic aroma detection technology for forensic and law enforcement applications

    Energy Technology Data Exchange (ETDEWEB)

    Barshick, S.-A.; Griest, W.H.; Vass, A.A.

    1996-12-31

    A major problem hindering criminal investigations is the lack of appropriate tools for proper crime scene investigations. Often locating important pieces of evidence means relying on the ability of trained detection canines. Development of analytical technology to uncover and analyze evidence, potentially at the scene, could serve to expedite criminal investigations, searches, and court proceedings. To address this problem, a new technology based on gas sensor arrays was investigated for its applicability to forensic and law enforcement problems. The technology employs an array of sensors that respond to volatile chemical components yielding a characteristic `fingerprint` pattern representative of the vapor- phase composition of a sample. Sample aromas can be analyzed and identified using artificial neural networks that are trained on known aroma patterns. Several candidate applications based on known technological needs of the forensic and law enforcement communities have been investigated. These applications have included the detection of aromas emanating from cadavers to aid in determining time since death, drug detection for deterring the manufacture, sale, and use of drugs of abuse, and the analysis of fire debris for accelerant identification. The results to date for these applications have been extremely promising and demonstrate the potential applicability of this technology for forensic use.

  10. Nanomaterials application in electrochemical detection of heavy metals

    International Nuclear Information System (INIS)

    Highlights: ► We review the recent trends in the application of nanomaterials for electrochemical detection of heavy metals. ► Different types of nanomaterials including metal nanoparticles, different carbon nanomaterials or nanochannels have been applied on the electrochemical analysis of heavy metals in various sensing formats/configurations. ► The great properties of nanomaterials allow the new devices to show advantages in terms of sensing performance (i.e. increase the sensitivity, decrease the detection limits and improve the stability). ► Between the various electrochemical techniques, voltammetric and potentiometric based ones are particularly taking interesting advantages by the incorporation of new nanomaterials due to the improved electrocatalytic properties beside the increase of the sensor's transducing area. - Abstract: Recent trends in the application of nanomaterials for electrochemical detection of heavy metals are shown. Various nanomaterials such as nanoparticles, nanowires, nanotubes, nanochannels, graphene, etc. have been explored either as modifiers of electrodes or as new electrode materials with interest to be applied in electrochemical stripping analysis, ion-selective detection, field-effect transistors or other indirect heavy metals (bio)detection alternatives. The developed devices have shown increased sensitivity and decreased detection limits between other improvements of analytical performance data. The phenomena behind nanomaterials responses are also discussed and some typical responses data of the developed systems either in standard solutions or in real samples are given. The developed nanomaterials based electrochemical systems are giving new inputs to the existing devices or leading to the development of novel heavy metal detection tools with interest for applications in field such as diagnostics, environmental and safety and security controls or other industries.

  11. Detecting long-term changes in point-source fossil CO2 emissions with tree ring archives

    Science.gov (United States)

    Keller, Elizabeth D.; Turnbull, Jocelyn C.; Norris, Margaret W.

    2016-05-01

    We examine the utility of tree ring 14C archives for detecting long-term changes in fossil CO2 emissions from a point source. Trees assimilate carbon from the atmosphere during photosynthesis, in the process faithfully recording the average atmospheric 14C content in each new annual tree ring. Using 14C as a proxy for fossil CO2, we examine interannual variability over six years of fossil CO2 observations between 2004-2005 and 2011-2012 from two trees growing near the Kapuni Gas Treatment Plant in rural Taranaki, New Zealand. We quantify the amount of variability that can be attributed to transport and meteorology by simulating constant point-source fossil CO2 emissions over the observation period with the atmospheric transport model WindTrax. We compare model simulation results to observations and calculate the amount of change in emissions that we can detect with new observations over annual or multi-year time periods, given both the measurement uncertainty of 1ppm and the modelled variation in transport. In particular, we ask, what is the minimum amount of change in emissions that we can detect using this method, given a reference period of six years? We find that changes of 42 % or more could be detected in a new sample from one year at the same observation location or 22 % in the case of four years of new samples. This threshold is reduced and the method becomes more practical the more the size of the signal increases. For point sources 10 times larger than the Kapuni plant (a more typical size for power plants worldwide), it would be possible to detect sustained emissions changes on the order of 10 %, given suitable meteorology and observations.

  12. Automated Rock Detection and Shape Analysis from Mars Rover Imagery and 3D Point Cloud Data

    Institute of Scientific and Technical Information of China (English)

    Kaichang Di; Zongyu Yue; Zhaoqin Liu; Shuliang Wang

    2013-01-01

    A new object-oriented method has been developed for the extraction of Mars rocks from Mars rover data.It is based on a combination of Mars rover imagery and 3D point cloud data.First,Navcam or Pancam images taken by the Mars rovers are segmented into homogeneous objects with a mean-shift algorithm.Then,the objects in the segmented images are classified into small rock candidates,rock shadows,and large objects.Rock shadows and large objects are considered as the regions within which large rocks may exist.In these regions,large rock candidates are extracted through ground-plane fitting with the 3D point cloud data.Small and large rock candidates are combined and postprocessed to obtain the final rock extraction results.The shape properties of the rocks (angularity,circularity,width,height,and width-height ratio) have been calculated for subsequent geological studies.

  13. Bayesian approach to change point detection of unemployment rate via MCMC methods

    Czech Academy of Sciences Publication Activity Database

    Reisnerová, Soňa

    Plzeň : University of West Bohemia in Pilsen, 2006 - (Lukáš, L.), s. 447-452 ISBN 978-80-7043-480-2. [Mathematical Methods in Economics 2006. Plzeň (CZ), 13.09.2006-15.09.2006] R&D Projects: GA AV ČR IAA101120604 Institutional research plan: CEZ:AV0Z10750506 Keywords : Change point * unemployment rate * MCMC * poisson model Subject RIV: BB - Applied Statistics, Operational Research

  14. Point Source Detection with Wavelets applied on Cosmic Microwave Radiation Maps

    OpenAIRE

    2008-01-01

    In between the Cosmic Microwave Background (CMB) and the instrument there are other sources of radiation, called foregrounds. The foregrounds radiate in the same frequency bands as the background, and cause contamination in the signal of the CMB. To ensure no wrong estimations of the power spectrum, these contaminants must be removed. There are several classes of contaminants, and this thesis has investigated techniques of removing the point sources (class of extragalactic sources), which occ...

  15. ROM Plus®: accurate point-of-care detection of ruptured fetal membranes

    OpenAIRE

    McQuivey RW; Block JE

    2016-01-01

    Ross W McQuivey,1 Jon E Block2 1Clinical Affairs, Clinical Innovations, Salt Lake City, UT, 2Independent Clinical Consultant, San Francisco, CA, USAAbstract: Accurate and timely diagnosis of rupture of fetal membranes is imperative to inform and guide gestational age-specific interventions to optimize perinatal outcomes and reduce the risk of serious complications, including preterm delivery and infections. The ROM Plus is a rapid, point-of-care, qualitative immunochromatographic diagnostic t...

  16. Detection of dim point targets in cluttered maritime backgrounds through multisensor image fusion

    NARCIS (Netherlands)

    Toet, A.

    2002-01-01

    Multispectral IR imaging techniques are frequently deployed in maritime operations, for instance to detect floating mines or to find small dinghies and swimmers during search and rescue operations. However, maritime backgrounds usually contain a large amount of clutter that severely hampers the dete

  17. Apparatus for point-of-care detection of nucleic acid in a sample

    Energy Technology Data Exchange (ETDEWEB)

    Bearinger, Jane P.; Dugan, Lawrence C.

    2016-04-19

    Provided herein are methods and apparatus for detecting a target nucleic acid in a sample and related methods and apparatus for diagnosing a condition in an individual. The condition is associated with presence of nucleic acid produced by certain pathogens in the individual.

  18. Designing efficient surveys: spatial arrangement of sample points for detection of invasive species

    Czech Academy of Sciences Publication Activity Database

    Berec, Luděk; Kean, J. M.; Epanchin-Niell, R.; Liebhold, A. M.; Haight, R. G.

    2015-01-01

    Roč. 17, č. 1 (2015), s. 445-459. ISSN 1387-3547 Grant ostatní: National Science Foundation(US) DEB-0553768 Institutional support: RVO:60077344 Keywords : biosecurity * early pest detection * eradication Subject RIV: EH - Ecology, Behaviour Impact factor: 2.586, year: 2014 http://link.springer.com/article/10.1007%2Fs10530-014-0742-x

  19. Implementation of a protein reduced point charge model toward molecular dynamics applications.

    Science.gov (United States)

    Leherte, Laurence; Vercauteren, Daniel P

    2011-11-17

    A reduced point charge model was developed in a previous work from the study of extrema in smoothed charge density distribution functions generated from the Amber99 molecular electrostatic potential. In the present work, such a point charge distribution is coupled with the Amber99 force field and implemented in the program TINKER to allow molecular dynamics (MD) simulations of proteins. First applications to two polypeptides that involve α-helix and β-sheet motifs are analyzed and compared to all-atom MD simulations. Two types of coarse-grained (CG)-based trajectories are generated using, on one hand, harmonic bond stretching terms and, on the other hand, distance restraints. Results show that the use of the unrestrained CG conditions are sufficient to preserve most of the secondary structure characteristics but restraints lead to a better agreement between CG and all-atom simulation results such as rmsd, dipole moment, and time-dependent mean square deviation functions. PMID:21800922

  20. Vein visualization using a smart phone with multispectral Wiener estimation for point-of-care applications.

    Science.gov (United States)

    Song, Jae Hee; Kim, Choye; Yoo, Yangmo

    2015-03-01

    Effective vein visualization is clinically important for various point-of-care applications, such as needle insertion. It can be achieved by utilizing ultrasound imaging or by applying infrared laser excitation and monitoring its absorption. However, while these approaches can be used for vein visualization, they are not suitable for point-of-care applications because of their cost, time, and accessibility. In this paper, a new vein visualization method based on multispectral Wiener estimation is proposed and its real-time implementation on a smart phone is presented. In the proposed method, a conventional RGB camera on a commercial smart phone (i.e., Galaxy Note 2, Samsung Electronics Inc., Suwon, Korea) is used to acquire reflectance information from veins. Wiener estimation is then applied to extract the multispectral information from the veins. To evaluate the performance of the proposed method, an experiment was conducted using a color calibration chart (ColorChecker Classic, X-rite, Grand Rapids, MI, USA) and an average root-mean-square error of 12.0% was obtained. In addition, an in vivo subcutaneous vein imaging experiment was performed to explore the clinical performance of the smart phone-based Wiener estimation. From the in vivo experiment, the veins at various sites were successfully localized using the reconstructed multispectral images and these results were confirmed by ultrasound B-mode and color Doppler images. These results indicate that the presented multispectral Wiener estimation method can be used for visualizing veins using a commercial smart phone for point-of-care applications (e.g., vein puncture guidance). PMID:24691170

  1. Application of hazard analysis and critical control point system in the dairy industry.

    Science.gov (United States)

    Kassem, M; Salem, E; Ahwal, A M; Saddik, M; Gomaa, N F

    2002-01-01

    This study aimed to assess the hygiene quality of some packaged milk (pasteurized or sterilized) and dairy products before and after application of a hazard analysis and critical control point (HACCP) system at a milk and dairy products company in Cairo, Egypt. The steps taken to put HACCP in place are described and the process was monitored to assess its impact. Assessment of the hygiene quality of the milk and dairy products before and after HACCP showed an improvement in quality and an overall improvement in the conditions at the company. PMID:15330567

  2. Fixed point theorems for M-contraction type maps in partially ordered metric spaces and applications

    Directory of Open Access Journals (Sweden)

    Sachin V. Bedre

    2014-09-01

    Full Text Available This paper presents hybrid fixed point theorems of Krasnosel’skii type and some nonlinear alternatives of Leray-Schauder type involving sums of two operators in a partially ordered normed linear spaces. The results are applied to functional integral equations that have been considered in Ntouyas and Tsamatos[21] for proving the existence of solutions under certain monotonic conditions blending with the existence of upper or lower solution. Applications are alsogiven to some nonlinear functional initial and boundary value problems ofordinary differential equations for proving the existence results.

  3. Applicability of point-dipoles approximation to all-dielectric metamaterials

    DEFF Research Database (Denmark)

    Kuznetsova, S. M.; Andryieuski, Andrei; Lavrinenko, Andrei

    2015-01-01

    All-dielectric metamaterials consisting of high-dielectric inclusions in a low-dielectric matrix are considered as a low-loss alternative to resonant metal-based metamaterials. In this paper we investigate the applicability of the point electric and magnetic dipoles approximation to dielectric meta......-atoms on the example of a dielectric ring metamaterial. Despite the large electrical size of high-dielectric meta-atoms, the dipole approximation allows for accurate prediction of the metamaterials properties for the rings with diameters up to approximate to 0.8 of the lattice constant. The results provide...

  4. Empirical likelihood based detection procedure for change point in mean residual life functions under random censorship.

    Science.gov (United States)

    Chen, Ying-Ju; Ning, Wei; Gupta, Arjun K

    2016-05-01

    The mean residual life (MRL) function is one of the basic parameters of interest in survival analysis that describes the expected remaining time of an individual after a certain age. The study of changes in the MRL function is practical and interesting because it may help us to identify some factors such as age and gender that may influence the remaining lifetimes of patients after receiving a certain surgery. In this paper, we propose a detection procedure based on the empirical likelihood for the changes in MRL functions with right censored data. Two real examples are also given: Veterans' administration lung cancer study and Stanford heart transplant to illustrate the detecting procedure. Copyright © 2016 John Wiley & Sons, Ltd. PMID:26936529

  5. Gravimetric Radar: Gravity-Based Detection of a Point-Mass Moving in a Static Background

    CERN Document Server

    Tannenbaum, Emmanuel David

    2012-01-01

    This paper discusses a novel approach for detecting moving massive objects based on the time variation that these objects produce in the local gravitational field measured by several detectors. Such an approach may provide a viable method for detecting stealth aircraft, UAVs, cruise, and ballistic missiles. By inverting a set of nonlinear algebraic equations, it is possible to use the time variation in the gravitational fields to compute the mass, position, and velocity of one or more moving objects. The approach is essentially a gravity-based form of triangulation. Based on order-of-magnitude calculations, we estimate that under realistic scenarios, this approach will be feasible if it is possible to design gravimetric devices that are four to five order of magnitude more sensitive than current devices. To achieve such a level of sensitivity, we suggest designing detectors that exploit a quantum-mechanical effect known as gravity-induced quantum interference. Furthermore, even if we have a perfect detector, ...

  6. POF hydrogen detection sensor systems for launch vehicles applications

    Science.gov (United States)

    Kazemi, Alex A.; Larson, David B.; Wuestling, Mark D.

    2011-06-01

    This paper describes the first successful Plastic Optical Fiber (POF) cable and glass fiber hydrogen detection sensor systems developed for Delta IV Launch Vehicle. Hydrogen detection in space application is very challenging; the hydrogen detection is priority for rocket industry and every transport device or any application where hydrogen is involved. H2 sensors are necessary to monitor the detection possible leak to avoid explosion, which can be highly dangerous. The hydrogen sensors had to perform in temperatures between -18° C to 60° C (0° F to 140° F). The response of the sensor in this temperature regime was characterized to ensure proper response of the sensors to fugitive hydrogen leakage during vehicle ground operations. We developed the first 75 m combination of POF and glass fiber H2 sensors. Performed detail investigation of POF-glass cables for attenuation loss, thermal, humidity, temperature, shock, accelerate testing for life expectancy. Also evaluated absorption, operating and high/low temperatures, and harsh environmental for glass-POF cables connectors. The same test procedures were performed for glass multi mode fiber part of the H2 and O2 sensors. A new optical waveguides was designed and developed to decrease the impact of both noise and long term drift of sensor. A field testing of sensors was performed at NASA Stennis on the Aerospike X-33 to quantify the element of the sensor package that was responsible for hydrogen detection and temperature.

  7. Automatic 3D Building Detection and Modeling from Airborne LiDAR Point Clouds

    Science.gov (United States)

    Sun, Shaohui

    2013-01-01

    Urban reconstruction, with an emphasis on man-made structure modeling, is an active research area with broad impact on several potential applications. Urban reconstruction combines photogrammetry, remote sensing, computer vision, and computer graphics. Even though there is a huge volume of work that has been done, many problems still remain…

  8. Ground penetrating radar applications for hazardous waste detection

    Science.gov (United States)

    Bashforth, Michael B.; Koppenjan, Steven

    1993-11-01

    The United States Department of Energy's Special Technologies Laboratory (STL) staff has been actively involved with ground penetrating radar technology since 1968. STL has developed a stepped FM-CW Ground Penetrating Radar (GPR). The initial application of this unit was the detection and imaging of unexploded ordnance. Since this time the target types have been expanded to subsurface storage containers, pipes and utility cables. Additionally, some field tests have been conducted where nonmetallic targets were of interest. Four case studies on the detection of buried ordnance and hazardous waste storage containers are discussed in this paper. A brief description of the STL GPR unit is presented.

  9. Web Application Security by SQL Injection DetectionTools

    Directory of Open Access Journals (Sweden)

    Atefeh Tajpour

    2012-03-01

    Full Text Available SQL injection is a type of attack which the attacker adds Structured Query Language code to a web form input box to gain access or make changes to data. SQL injection vulnerability allows an attacker to flow commands directly to a web application underlying database and destroy functionality or confidentiality. Researchers have proposed different tools to detect and prevent this vulnerability. In this paper we present all SQL injection attack types and also current tools which can detect or prevent these attacks. Finally we evaluate these tools.

  10. Application of atomic magnetometry in magnetic particle detection

    CERN Document Server

    Xu, S; Donaldson, M H; Pines, A; Rochester, S M; Yashchuk, V V

    2006-01-01

    We demonstrate the detection of magnetic particles carried by water in a continuous flow using an atomic magnetic gradiometer. Studies on three types of magnetic particles are presented: a single cobalt particle (diameter ~150 um, multi-domain), a suspension of superparamagnetic magnetite particles (diameter \\~1 um), and ferromagnetic cobalt nanoparticles (diameter ~10 nm, 120 kA/m magnetization). Estimated detection limits are 20 um diameter for a single cobalt particle at a water flow rate 30 ml/min, 5x10^3 magnetite particles at 160 ml/min, and 50 pl for the specific ferromagnetic fluid at 130 ml/min. Possible applications of our method are discussed.

  11. Airborne Light Detection and Ranging (lidar) Derived Deformation from the MW 6.0 24 August, 2014 South Napa Earthquake Estimated by Two and Three Dimensional Point Cloud Change Detection Techniques

    Science.gov (United States)

    Lyda, A. W.; Zhang, X.; Glennie, C. L.; Hudnut, K.; Brooks, B. A.

    2016-06-01

    Remote sensing via LiDAR (Light Detection And Ranging) has proven extremely useful in both Earth science and hazard related studies. Surveys taken before and after an earthquake for example, can provide decimeter-level, 3D near-field estimates of land deformation that offer better spatial coverage of the near field rupture zone than other geodetic methods (e.g., InSAR, GNSS, or alignment array). In this study, we compare and contrast estimates of deformation obtained from different pre and post-event airborne laser scanning (ALS) data sets of the 2014 South Napa Earthquake using two change detection algorithms, Iterative Control Point (ICP) and Particle Image Velocimetry (PIV). The ICP algorithm is a closest point based registration algorithm that can iteratively acquire three dimensional deformations from airborne LiDAR data sets. By employing a newly proposed partition scheme, "moving window," to handle the large spatial scale point cloud over the earthquake rupture area, the ICP process applies a rigid registration of data sets within an overlapped window to enhance the change detection results of the local, spatially varying surface deformation near-fault. The other algorithm, PIV, is a well-established, two dimensional image co-registration and correlation technique developed in fluid mechanics research and later applied to geotechnical studies. Adapted here for an earthquake with little vertical movement, the 3D point cloud is interpolated into a 2D DTM image and horizontal deformation is determined by assessing the cross-correlation of interrogation areas within the images to find the most likely deformation between two areas. Both the PIV process and the ICP algorithm are further benefited by a presented, novel use of urban geodetic markers. Analogous to the persistent scatterer technique employed with differential radar observations, this new LiDAR application exploits a classified point cloud dataset to assist the change detection algorithms. Ground

  12. THE FUSION OF INDIVIDUAL TREE DETECTION AND VISUAL INTERPRETATION IN ASSESSMENT OF FOREST VARIABLES FROM LASER POINT CLOUDS

    Directory of Open Access Journals (Sweden)

    V. Kankare

    2012-09-01

    Full Text Available In this study we searched the obtainable accuracy of forest inventory based on the individual tree detection (ITD by using fusion of automatic ITD (ITDauto and visual interpretation of laser point clouds. Current ITD algorithms, mostly based on segmentation of canopy height models (CHMs, are not able to utilize the whole information included in three-dimensional point clouds. We hypothesized that visual interpretation of the point cloud could provide so-called "best case" tree detection that could be achievable automatically. We refer to this method consisting of ITDauto and visual interpretation as ITDvisual. We assessed the plot level accuracies of the ITDauto and ITDvisual in boreal managed forest conditions using 322 plots. Based on the results the accuracy of ITD can be improved with visual interpretation. Omission trees are mainly missing from both ITD-methods. ITDvisual produced more accurate estimates for all forest variables compared to ITDauto, e.g. RMSE% in volume decreased from 33.3% to 27.8% and bias% in volume from 4.1% to 2.3%. Area-based approach (ABA is becoming more general for operational forest inventories with sparser laser data. ITDvisual would be justified if it could replace expensive field work in plot-wise measurements needed for ABA. Further research is needed in the use of ITD results as a reference for ABA.

  13. Fault Tolerance Approach in Mobile Agents for Information Retrieval Applications Using Check Points

    Directory of Open Access Journals (Sweden)

    Rahul Hans

    2012-06-01

    Full Text Available Mobile agents have emerged as major programming paradigm for distributed applications. Mobile agents are the intelligent programs that act autonomously on behalf of a user and can migrate from one host to another host in a network in order to satisfy the requests made by their clients. A prerequisite for their use, however, is that they should be executed reliably independent of failures. Improving the survivability of mobile agents in presence of agent server failures is an important issue in order to guarantee continuous execution of mobile agents. Thus it is very important to make mobile agents fault tolerant. In this paper, we propose fault tolerance mechanism for the scenarios where the agent stops its execution due to fault on any server in the itinerary. Our approach makes use of check pointing, partial results or data retrieved and the address of last host visited is saved prior before the agent visits the next host in the itinerary .The proposed mechanism has been implemented on the Aglets mobile agent system and evaluated in terms of parameters such as round trip time, Reliable migration time, Check point time. The results show the improvement in reliability and performance, especially for mobile agents in Internet application.

  14. Application of hazard analysis critical control points (HACCP) to organic chemical contaminants in food.

    Science.gov (United States)

    Ropkins, K; Beck, A J

    2002-03-01

    Hazard Analysis Critical Control Points (HACCP) is a systematic approach to the identification, assessment, and control of hazards that was developed as an effective alternative to conventional end-point analysis to control food safety. It has been described as the most effective means of controlling foodborne diseases, and its application to the control of microbiological hazards has been accepted internationally. By contrast, relatively little has been reported relating to the potential use of HACCP, or HACCP-like procedures, to control chemical contaminants of food. This article presents an overview of the implementation of HACCP and discusses its application to the control of organic chemical contaminants in the food chain. Although this is likely to result in many of the advantages previously identified for microbiological HACCP, that is, more effective, efficient, and economical hazard management, a number of areas are identified that require further research and development. These include: (1) a need to refine the methods of chemical contaminant identification and risk assessment employed, (2) develop more cost-effective monitoring and control methods for routine chemical contaminant surveillance of food, and (3) improve the effectiveness of process optimization for the control of chemical contaminants in food. PMID:11934130

  15. DETECT: a MATLAB toolbox for event detection and identification in time series, with applications to artifact detection in EEG signals.

    Directory of Open Access Journals (Sweden)

    Vernon Lawhern

    Full Text Available Recent advances in sensor and recording technology have allowed scientists to acquire very large time-series datasets. Researchers often analyze these datasets in the context of events, which are intervals of time where the properties of the signal change relative to a baseline signal. We have developed DETECT, a MATLAB toolbox for detecting event time intervals in long, multi-channel time series. Our primary goal is to produce a toolbox that is simple for researchers to use, allowing them to quickly train a model on multiple classes of events, assess the accuracy of the model, and determine how closely the results agree with their own manual identification of events without requiring extensive programming knowledge or machine learning experience. As an illustration, we discuss application of the DETECT toolbox for detecting signal artifacts found in continuous multi-channel EEG recordings and show the functionality of the tools found in the toolbox. We also discuss the application of DETECT for identifying irregular heartbeat waveforms found in electrocardiogram (ECG data as an additional illustration.

  16. Edge detection and its application to recognition of arc weld image

    Institute of Scientific and Technical Information of China (English)

    Chen Xizhang; Lin Tao; Lang Yuyou; Chen Shanben

    2007-01-01

    Image sensor has been one of the key technologies in intellectualized robotics welding. Edge detection plays an important role when the vision technology is applied in intellectualized welding robotics technologies. There are all kinds of noises in welding environment. The algorithms in common use cannot be applied to the recognition of welding environment directly. The edge of images can be fell into four types. The weld images are classified by the characteristic of welding environment in this paper. This paper analyzes some algorithms of edge detection according to the character of welding image, some relative advantages and disadvantages are pointed out when these algorithms are used in this field, and some suggestions are given. The feature extraction of weld seam and weld pool are two typical problems in the realization of intellectualized welding. Their edge features are extracted and the results show the applicability of different edge detectors. The tradeoff between precision and calculated time is also considered for different application.

  17. Multi-point accelerometric detection and principal component analysis of heart sounds

    International Nuclear Information System (INIS)

    Heart sounds are a fundamental physiological variable that provide a unique insight into cardiac semiotics. However a deterministic and unambiguous association between noises in cardiac dynamics is far from being accomplished yet due to many and different overlapping events which contribute to the acoustic emission. The current computer-based capacities in terms of signal detection and processing allow one to move from the standard cardiac auscultation, even in its improved forms like electronic stethoscopes or hi-tech phonocardiography, to the extraction of information on the cardiac activity previously unexplored. In this report, we present a new equipment for the detection of heart sounds, based on a set of accelerometric sensors placed in contact with the chest skin on the precordial area, and are able to measure simultaneously the vibration induced on the chest surface by the heart's mechanical activity. By utilizing advanced algorithms for the data treatment, such as wavelet decomposition and principal component analysis, we are able to condense the spatially extended acoustic information and to provide a synthetical representation of the heart activity. We applied our approach to 30 adults, mixed per gender, age and healthiness, and correlated our results with standard echocardiographic examinations. We obtained a 93% concordance rate with echocardiography between healthy and unhealthy hearts, including minor abnormalities such as mitral valve prolapse. (fast track communication)

  18. Effect of time-of-flight and point spread function modeling on detectability of myocardial defects in PET

    International Nuclear Information System (INIS)

    Purpose: A study was designed to investigate the impact of time-of-flight (TOF) and point spread function (PSF) modeling on the detectability of myocardial defects. Methods: Clinical FDG-PET data were used to generate populations of defect-present and defect-absent images. Defects were incorporated at three contrast levels, and images were reconstructed by ordered subset expectation maximization (OSEM) iterative methods including ordinary Poisson, alone and with PSF, TOF, and PSF+TOF. Channelized Hotelling observer signal-to-noise ratio (SNR) was the surrogate for human observer performance. Results: For three iterations, 12 subsets, and no postreconstruction smoothing, TOF improved overall defect detection SNR by 8.6% as compared to its non-TOF counterpart for all the defect contrasts. Due to the slow convergence of PSF reconstruction, PSF yielded 4.4% less SNR than non-PSF. For reconstruction parameters (iteration number and postreconstruction smoothing kernel size) optimizing observer SNR, PSF showed larger improvement for faint defects. The combination of TOF and PSF improved mean detection SNR as compared to non-TOF and non-PSF counterparts by 3.0% and 3.2%, respectively. Conclusions: For typical reconstruction protocol used in clinical practice, i.e., less than five iterations, TOF improved defect detectability. In contrast, PSF generally yielded less detectability. For large number of iterations, TOF+PSF yields the best observer performance

  19. Effect of time-of-flight and point spread function modeling on detectability of myocardial defects in PET

    Energy Technology Data Exchange (ETDEWEB)

    Schaefferkoetter, Joshua, E-mail: dnrjds@nus.edu.sg [A-STAR-NUS Clinical Imaging and Research Centre (CIRC), Singapore 117599 (Singapore); Ouyang, Jinsong; Rakvongthai, Yothin; El Fakhri, Georges [Center for Advanced Medical Imaging Sciences, Division of Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital, Boston, Massachusetts 02114 and Radiology Department, Harvard Medical School, Boston, Massachusetts 02115 (United States); Nappi, Carmela [Radiology Department, Harvard Medical School, Boston, Massachusetts 02115 Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples 80131 (Italy); SDN Foundation, Institute of Diagnostic and Nuclear Development, Naples 80142 (Italy)

    2014-06-15

    Purpose: A study was designed to investigate the impact of time-of-flight (TOF) and point spread function (PSF) modeling on the detectability of myocardial defects. Methods: Clinical FDG-PET data were used to generate populations of defect-present and defect-absent images. Defects were incorporated at three contrast levels, and images were reconstructed by ordered subset expectation maximization (OSEM) iterative methods including ordinary Poisson, alone and with PSF, TOF, and PSF+TOF. Channelized Hotelling observer signal-to-noise ratio (SNR) was the surrogate for human observer performance. Results: For three iterations, 12 subsets, and no postreconstruction smoothing, TOF improved overall defect detection SNR by 8.6% as compared to its non-TOF counterpart for all the defect contrasts. Due to the slow convergence of PSF reconstruction, PSF yielded 4.4% less SNR than non-PSF. For reconstruction parameters (iteration number and postreconstruction smoothing kernel size) optimizing observer SNR, PSF showed larger improvement for faint defects. The combination of TOF and PSF improved mean detection SNR as compared to non-TOF and non-PSF counterparts by 3.0% and 3.2%, respectively. Conclusions: For typical reconstruction protocol used in clinical practice, i.e., less than five iterations, TOF improved defect detectability. In contrast, PSF generally yielded less detectability. For large number of iterations, TOF+PSF yields the best observer performance.

  20. Terahertz and Mid Infrared Radiation Generation, Detection and Applications

    CERN Document Server

    Pereira, Mauro F

    2011-01-01

    Terahertz (THz) and Mid-Infrared (MIR) radiation  (TERA-MIR) can be transmitted through nearly any material without causing biological harm. Novel and rapid methods of detection can be created with devices operation in these spectral ranges allowing scanning for weapons, detecting hidden explosives (including plastic landmines), controlling the quality of food and a host of other exciting applications.  This book focuses on mathematical and physical aspects of the field, on unifying these two spectral domains (THz and MIR) with regard to common sources, detectors, materials and applications, and on key interdisciplinary topics. The main THz and MIR source is the quantum cascade laser (QCL). Thus significant attention is paid to the challenge of turning this advanced technology into affordable commercial devices so as to exploit its enormous potential. However other alternatives to THz QCLs are also presented, e.g.  sub-terahertz imaging from avalanching GaAs bipolar transistors, Josephson junctions as THz ...

  1. Preliminary studies on DNA retardation by MutS applied to the detection of point mutations in clinical samples

    International Nuclear Information System (INIS)

    MutS ability to bind DNA mismatches was applied to the detection of point mutations in PCR products. MutS recognized mismatches from single up to five nucleotides and retarded the electrophoretic migration of mismatched DNA. The electrophoretic detection of insertions/deletions above three nucleotides is also possible without MutS, thanks to the DNA mobility shift caused by the presence of large insertion/deletion loops in the heteroduplex DNA. Thus, the method enables the search for a broad range of mutations: from single up to several nucleotides. The mobility shift assays were carried out in polyacrylamide gels stained with SYBR-Gold. One assay required 50-200 ng of PCR product and 1-3 μg of Thermus thermophilus his6-MutS protein. The advantages of this approach are: the small amounts of DNA required for the examination, simple and fast staining, no demand for PCR product purification, no labelling and radioisotopes required. The method was tested in the detection of cancer predisposing mutations in RET, hMSH2, hMLH1, BRCA1, BRCA2 and NBS1 genes. The approach appears to be promising in screening for unknown point mutations

  2. A Colorimetric Enzyme-Linked Immunosorbent Assay (ELISA Detection Platform for a Point-of-Care Dengue Detection System on a Lab-on-Compact-Disc

    Directory of Open Access Journals (Sweden)

    Aung Thiha

    2015-05-01

    Full Text Available The enzyme-linked Immunosorbent Assay (ELISA is the gold standard clinical diagnostic tool for the detection and quantification of protein biomarkers. However, conventional ELISA tests have drawbacks in their requirement of time, expensive equipment and expertise for operation. Hence, for the purpose of rapid, high throughput screening and point-of-care diagnosis, researchers are miniaturizing sandwich ELISA procedures on Lab-on-a-Chip and Lab-on-Compact Disc (LOCD platforms. This paper presents a novel integrated device to detect and interpret the ELISA test results on a LOCD platform. The system applies absorption spectrophotometry to measure the absorbance (optical density of the sample using a monochromatic light source and optical sensor. The device performs automated analysis of the results and presents absorbance values and diagnostic test results via a graphical display or via Bluetooth to a smartphone platform which also acts as controller of the device. The efficacy of the device was evaluated by performing dengue antibody IgG ELISA on 64 hospitalized patients suspected of dengue. The results demonstrate high accuracy of the device, with 95% sensitivity and 100% specificity in detection when compared with gold standard commercial ELISA microplate readers. This sensor platform represents a significant step towards establishing ELISA as a rapid, inexpensive and automatic testing method for the purpose of point-of-care-testing (POCT in resource-limited settings.

  3. Decision Cost Feature Weighting and Its Application in Intrusion Detection

    Institute of Scientific and Technical Information of China (English)

    QIAN Quan; GENG Huan-tong; WANG Xu-fa

    2004-01-01

    This paper introduces the cost-sensitive feature weighting strategy and its application in intrusion detection.Cost factors and cost matrix are proposed to demonstrate the misclassification cost for IDS.How to get the whole minimal risk, is mainly discussed in this paper in detail.From experiments, it shows that although decision cost based weight learning exists somewhat attack misclassification, it can achieve relatively low misclassification costs on the basis of keeping relatively high rate of recognition precision.

  4. Point-of-care detection and real-time monitoring of intravenously delivered drugs via tubing with an integrated SERS sensor

    Science.gov (United States)

    Wu, Hsin-Yu; Cunningham, Brian T.

    2014-04-01

    We demonstrate an approach for detection, identification, and kinetic monitoring of drugs flowing within tubing, through the use of a plasmonic nanodome array (PNA) surface. The PNA structures are fabricated using a low-cost nanoreplica molding process upon a flexible plastic substrate that is subsequently integrated with a flow cell that connects in series with ordinary intravenous (IV) drug delivery tubing. To investigate the potential clinical applications for point-of-care detection and real-time monitoring, we perform SERS detection of ten pharmaceutical compounds (hydrocodone, levorphanol, morphine, oxycodone, methadone, phenobarbital, dopamine, diltiazem, promethazine, and mitoxantrone). We demonstrate dose-dependent SERS signal magnitude, resulting in detection limits (ng ml-1) well below typical administered dosages (mg ml-1). Further, we show that the detected drugs are not permanently attached to the PNA surface, and thus our approach is capable of performing continuous monitoring of drug delivery as materials flow through IV tubing that is connected in series with the sensor. Finally, we demonstrate the potential co-detection of multiple drugs when they are mixed together, and show excellent reproducibility and stability of SERS measurements for periods extending at least five days. The capabilities reported here demonstrate the potential to use PNA SERS surfaces for enhancing the safety of IV drug delivery.We demonstrate an approach for detection, identification, and kinetic monitoring of drugs flowing within tubing, through the use of a plasmonic nanodome array (PNA) surface. The PNA structures are fabricated using a low-cost nanoreplica molding process upon a flexible plastic substrate that is subsequently integrated with a flow cell that connects in series with ordinary intravenous (IV) drug delivery tubing. To investigate the potential clinical applications for point-of-care detection and real-time monitoring, we perform SERS detection of ten

  5. Laser desorption mass spectrometry for biomolecule detection and its applications

    International Nuclear Information System (INIS)

    During the past few years, we developed and used laser desorption mass spectrometry for biomolecule detections. Matrix-assisted laser desorption/ionization (MALDI) was successfully used to detect DNA fragments with the size larger than 3000 base pairs. It was also successfully used to sequence DNA with both enzymatic and chemical degradation methods to produce DNA ladders. We also developed MALDI with fragmentation for direct DNA sequencing for short DNA probes. Since laser desorption mass spectrometry for DNA detection has the advantages of fast speed and no need of labeling, it has a great potential for molecular diagnosis for disease and person identification by DNA fingerprinting. We applied laser desorption mass spectrometry to succeed in the diagnosis of cystic fibrosis and several other nerve degenerative diseases such as Huntington's disease. We also succeeded in demonstrating DNA typing for forensic applications

  6. Aerial Neutron Detection: Neutron Signatures for Nonproliferation and Emergency Response Applications

    Energy Technology Data Exchange (ETDEWEB)

    Maurer, Richard J.; Stampahar, Thomas G.; Smith, Ethan X.; Mukhopadhyay, Sanjoy; Wolff, Ronald S.; Rourke, Timothy J.; LeDonne, Jeffrey P.; Avaro, Emanuele; Butler, D. Andre; Borders, Kevin L.; Stampahar, Jezabel; Schuck, William H.; Selfridge, Thomas L.; McKissack, Thomas M.; Duncan, William W.; Hendricks, Thane J.

    2012-10-17

    From 2007 to the present, the Remote Sensing Laboratory has been conducting a series of studies designed to expand our fundamental understanding of aerial neutron detection with the goal of designing an enhanced sensitivity detection system for long range neutron detection. Over 35 hours of aerial measurements in a helicopter were conducted for a variety of neutron emitters such as neutron point sources, a commercial nuclear power reactor, nuclear reactor spent fuel in dry cask storage, depleted uranium hexafluoride and depleted uranium metal. The goals of the project were to increase the detection sensitivity of our instruments such that a 5.4 × 104 neutron/second source could be detected at 100 feet above ground level at a speed of 70 knots and to enhance the long-range detection sensitivity for larger neutron sources, i.e., detection ranges above 1000 feet. In order to increase the sensitivity of aerial neutron detection instruments, it is important to understand the dynamics of the neutron background as a function of altitude. For aerial neutron detection, studies have shown that the neutron background primarily originates from above the aircraft, being produced in the upper atmosphere by galactic cosmic-ray interactions with air molecules. These interactions produce energetic neutrons and charged particles that cascade to the earth’s surface, producing additional neutrons in secondary collisions. Hence, the neutron background increases as a function of altitude which is an impediment to long-range neutron detection. In order to increase the sensitivity for long range detection, it is necessary to maintain a low neutron background as a function of altitude. Initial investigations show the variation in the neutron background can be decreased with the application of a cosmic-ray shield. The results of the studies along with a representative data set are presented.

  7. Rapid detection of Avian Influenza Virus - Towards point of care diagnosis

    DEFF Research Database (Denmark)

    Dhumpa, Raghuram

    Ab) conjugated magnetic beads where RNA extraction step is not required. The developed bead-based system was able to capture, concentrate and purify all of the 16 H subtypes of AIV from the AIV spiked faecal samples, demonstrating the efficiency of the mAb conjugated beads and the developed method. Subsequently......, the newly developed beadiv based method was used in a microfluidic magnetic microsystem for the automation of sample preparation. Using LOC system with a Cyclic-Olefin-Copolymer (COC) polymer chip, the RTPCR was miniaturized and the entire process was detected in less than 2 h. This integrated LOC...... virus subtypes of H5 and H7. This solid-phase RT-PCR method combines a reverse-transcription amplification of RNA extract in the liquid-phase with sequence-specific nested PCR on the solid phase. The examination of 33 avian faecal and tracheal swab specimens was completed in less than 2 h with 94...

  8. Derivation of Pal-Bell equations for two-point reactors, and its application to correlation measurements at KUCA

    International Nuclear Information System (INIS)

    A probability is defined for an event in which m neutrons exist at time t sub(f) in core I of a coupled-core system, originating from a neutron injected into the core I at an earlier time t; we call it P sub(I,I,m)(t sub(f)/t). Similarly, P sub(I,II,m)(t sub(f)/t) is defined as the probability for m neutrons to exist in core II of the system at time t sub(f), originating from a neutron injected into the core I at time t. Then a system of coupled equations are derived for the generating functions G sub(Ij)(z, t sub(f)/t) = μP sub(Ijm)(t sub(f)/t).z sup(m), where j = I, II. By similar procedures equations are derived for the generating functions associated with joint probability of the following events: a given combination of numbers of neutrons are detected during given series of detection time intervals by a detector inserted in one of the cores. The above two kinds of systems of equations can be regarded as a two-point version of Pal-Bell's equations. As the application of these formulations, analyzing formula for correlation measurements, namely (1) Feynman-alpha experiment and (2) Rossi-alpha experiment of Orndoff-type, are derived, and their feasibility is verified by experiments carried out at KUCA. (author)

  9. Radioisotope tracer instrument and its application to the detection of the groundwater parameters

    International Nuclear Information System (INIS)

    The application of radioisotope tracer technique and probe can result in the detection of groundwater flow direction, flow velocity and vertical currents in one single well. The tracer probe consists of the source injector and the components related with direction detection, location and velocity measurement. The nuclear detector employs a thermoluminescence detector (TLD) and a direct reading ionization chamber (IC) for the detection of flow direction and also employs a new method of photofluorography location for the determination of the probe's northern or southern position in the well, thereby greatly simplifying the design of the direction-detecting probe. The velocity measuring section includes ground receiving instruments and meters for conducting point or whole-borehole measurement. It is also possible to carry out interconnection tests and dispersion tests. With the applications to the ascertaining of the groundwater distribution in the karst region as well as the execution of the dispersion tests related with environmental protection and so on, it has been confirmed that the radioisotope tracer instrument has a broad scope of application and practicability. (author). 5 refs, 6 figs

  10. Analysis of In-Situ Vibration Monitoring for End-Point Detection of CMP Planarization Processes

    Energy Technology Data Exchange (ETDEWEB)

    Hetherington, Dale L.; Lauffer, James P.; Shingledecker, David M.; Stein, David J.; Wyckoff, Edward E.

    1999-05-14

    This paper details the analysis of vibration monitoring for end-point control in oxide CMP processes. Two piezoelectric accelerometers were integrated onto the backside of a stainless steel polishing head of an IPEC 472 polisher. One sensor was placed perpendicular to the carrier plate (vertical) and the other parallel to the plate (horizontal). Wafers patterned with metal and coated with oxide material were polished at different speeds and pressures. Our results show that it is possible to sense a change in the vibration signal over time during planarization of oxide material on patterned wafers. The horizontal accelerometer showed more sensitivity to change in vibration amplitude compared to the vertical accelerometer for a given polish condition. At low carrier and platen rotation rates, the change in vibration signal over time at fixed frequencies decreased approximately ½ - 1 order of magnitude (over the 2 to 10 psi polish pressure ranges). At high rotation speeds, the vibration signal remained essentially constant indicating that other factors dominated the vibration signaL These results show that while it is possible to sense changes in acceleration during polishing, more robust hardware and signal processing algorithms are required to ensure its use over a wide range of process conditions.

  11. Investigation of Point Doppler Velocimetry (PDV) for Transition Detection in Boundary Layers

    Science.gov (United States)

    Kuhlman, John M.

    1999-01-01

    A two component Point Doppler Velocimetry (PDV) system has been developed and tested. Improvements were made to an earlier PDV system, in terms of experimental techniques, as well as the data acquisition and reduction software. Measurements of the streamwise and spanwise mean and fluctuating velocities for flows from a rectangular channel and over an NACA 0012 airfoil were made, and the data were compared against hot wire data. The closest to the airfoil surface that PDV measurements could be made was on the order of 0.005 m(0.2", z/c = 0.0169). When the PDV and hot wire data were compared, the time traces for each appeared similar. The mean velocities agreed to within plus or minus 2 m/sec, while the RMS velocities agreed to plus or minus 0.4 m/sec. While the PDV time autocorrelations agreed with those of the hot wire data, the PDV power spectral densities were noisier above 750 Hz. A major source of error in these experiments was determined to be the drifting of the iodine cell stem temperatures. While the stem temperatures were controlled to within plus or minus 0.1 C, this could lead to a frequency shift of as much as 6 MHz, which translates into an error of 1.6 m/sec for the back scatter channel, and up to 6.9 m/sec for the forward scatter channel. These error estimates are consistent with the observed error magnitudes.

  12. Modified titrimetric determination of plutonium using photometric end-point detection

    International Nuclear Information System (INIS)

    A method used at LASL for the accurate and precise assay of plutonium metal was modified for the measurement of plutonium in plutonium oxides, nitrate solutions, and in other samples containing large quantities of plutonium in oxidized states higher than +3. In this modified method, the plutonium oxide or other sample is dissolved using the sealed-reflux dissolution method or other appropriate methods. Weighed aliquots, containing approximately 100 mg of plutonium, of the dissolved sample or plutonium nitrate solution are fumed to dryness with an HC1O4-H2SO4 mixture. The dried residue is dissolved in dilute H2SO4, and the plutonium is reduced to plutonium (III) with zinc metal. The excess zinc metal is dissolved with HCl, and the solution is passed through a lead reductor column to ensure complete reduction of the plutonium to plutonium (III). The solution, with added ferroin indicator, is then titrated immediately with standardized ceric solution to a photometric end point. For the analysis of plutonium metal solutions, plutonium oxides, and nitrate solutions, the relative standard deviation are 0.06, 0.08, and 0.14%, respectively. Of the elements most likely to be found with the plutonium, only iron, neptunium, and uranium interfere. Small amounts of uranium and iron, which titrate quantitatively in the method, are determined by separate analytical methods, and suitable corrections are applied to the plutonium value. 4 tables, 4 figures

  13. Point Defects in Two-Dimensional Layered Semiconductors: Physics and Its Applications

    Science.gov (United States)

    Suh, Joonki

    Recent advances in material science and semiconductor processing have been achieved largely based on in-depth understanding, efficient management and advanced application of point defects in host semiconductors, thus finding the relevant techniques such as doping and defect engineering as a traditional scientific and technological solution. Meanwhile, two- dimensional (2D) layered semiconductors currently draw tremendous attentions due to industrial needs and their rich physics at the nanoscale; as we approach the end of critical device dimensions in silicon-based technology, ultra-thin semiconductors have the potential as next- generation channel materials, and new physics also emerges at such reduced dimensions where confinement of electrons, phonons, and other quasi-particles is significant. It is therefore rewarding and interesting to understand and redefine the impact of lattice defects by investigating their interactions with energy/charge carriers of the host matter. Potentially, the established understanding will provide unprecedented opportunities for realizing new functionalities and enhancing the performance of energy harvesting and optoelectronic devices. In this thesis, multiple novel 2D layered semiconductors, such as bismuth and transition- metal chalcogenides, are explored. Following an introduction of conventional effects induced by point defects in semiconductors, the related physics of electronically active amphoteric defects is revisited in greater details. This can elucidate the complication of a two-dimensional electron gas coexisting with the topological states on the surface of bismuth chalcogenides, recently suggested as topological insulators. Therefore, native point defects are still one of the keys to understand and exploit topological insulators. In addition to from a fundamental science point of view, the effects of point defects on the integrated thermal-electrical transport, as well as the entropy-transporting process in

  14. Method to detect the end-point for PCR DNA amplification using an ionically labeled probe and measuring impedance change

    Science.gov (United States)

    Miles, Robin R.; Belgrader, Phillip; Fuller, Christopher D.

    2007-01-02

    Impedance measurements are used to detect the end-point for PCR DNA amplification. A pair of spaced electrodes are located on a surface of a microfluidic channel and an AC or DC voltage is applied across the electrodes to produce an electric field. An ionically labeled probe will attach to a complementary DNA segment, and a polymerase enzyme will release the ionic label. This causes the conductivity of the solution in the area of the electrode to change. This change in conductivity is measured as a change in the impedance been the two electrodes.

  15. DETECTION OF PLANAR POINTS FOR BUILDING EXTRACTION FROM LIDAR DATA BASED ON DIFFERENTIAL MORPHOLOGICAL AND ATTRIBUTE PROFILES

    OpenAIRE

    Mongus, D.; Lukač, N.; Obrul, D.; Žalik, B.

    2013-01-01

    This paper considers a new method for building-extraction from LiDAR data. This method uses multi-scale levelling schema or MSLS-segmentation based on differential morphological profiles for removing non-building points from LiDAR data during the data denoising step. A new morphological algorithm is proposed for the detection of flat regions and obtaining a set of building-candidates. This binarisation step is made by using differential attribute profiles based on the sum of the seco...

  16. Novel Point-of-Care Test for Simultaneous Detection of Nontreponemal and Treponemal Antibodies in Patients with Syphilis ▿

    OpenAIRE

    Castro, Arnold R.; Esfandiari, Javan; Kumar, Shailendra; Ashton, Matthew (British painter, active from 1728); Kikkert, Susan E.; Park, Mahin M.; Ballard, Ronald C.

    2010-01-01

    We describe a point-of-care immunochromatographic test for the simultaneous detection of both nontreponemal and treponemal antibodies in the sera of patients with syphilis that acts as both a screening and a confirmatory test. A total of 1,601 banked serum samples were examined by the dual test, and the results were compared to those obtained using a quantitative rapid plasma reagin (RPR) test and the Treponema pallidum passive particle agglutination (TP-PA) assay. Compared to the RPR test, t...

  17. On the adaptive partition approach to the detection of multiple change-points.

    Directory of Open Access Journals (Sweden)

    Yinglei Lai

    Full Text Available With an adaptive partition procedure, we can partition a "time course" into consecutive non-overlapped intervals such that the population means/proportions of the observations in two adjacent intervals are significantly different at a given level . However, the widely used recursive combination or partition procedures do not guarantee a global optimization. We propose a modified dynamic programming algorithm to achieve a global optimization. Our method can provide consistent estimation results. In a comprehensive simulation study, our method shows an improved performance when it is compared to the recursive combination/partition procedures. In practice, can be determined based on a cross-validation procedure. As an application, we consider the well-known Pima Indian Diabetes data. We explore the relationship among the diabetes risk and several important variables including the plasma glucose concentration, body mass index and age.

  18. Clinical impact of time-of-flight and point response modeling in PET reconstructions: a lesion detection study

    International Nuclear Information System (INIS)

    Time-of-flight (TOF) and point spread function (PSF) modeling have been shown to improve PET reconstructions, but the impact on physicians in the clinical setting has not been thoroughly investigated. A lesion detection and localization study was performed using simulated lesions in real patient images. Four reconstruction schemes were considered: ordinary Poisson OSEM (OP) alone and combined with TOF, PSF, and TOF + PSF. The images were presented to physicians experienced in reading PET images, and the performance of each was quantified using localization receiver operating characteristic. Numerical observers (non-prewhitening and Hotelling) were used to identify optimal reconstruction parameters, and observer SNR was compared to the performance of the physicians. The numerical models showed good agreement with human performance, and best performance was achieved by both when using TOF + PSF. These findings suggest a large potential benefit of TOF + PSF for oncology PET studies, especially in the detection of small, low-intensity, focal disease in larger patients. (paper)

  19. Detection of the end point temperature of thermal denatured protein in fish and chicken meat through SDS-PAGE electrophoresis

    Science.gov (United States)

    Gao, Hongwei; Mao, Mao; Liang, Chengzhu; Lin, Chao; Xiang, Jianhai

    2009-03-01

    Sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) was applied in the detection of the end point temperature (EPT) of thermal denatured protein in fish and meat in this study. It was also used in studying the thermal denatured temperature range of proteins in salmon and chicken meat. The results show that the temperature ranges of denatured proteins were from 65°C to 75°C, and these temperature ranges were influenced by the processing methods. Through SDS-PAGE, the features of repeated heating thermal denatured proteins under the same temperature and processing time were studied. The electrophoresis patterns of thermal denatured proteins determined through repeated heating at the same temperature did not exhibit any change. For the detection of cooked fish and meat samples, they were subjected to applying the SDS-PAGE method, which revealed an EPT ranging from 60°C to 80°C.

  20. False-alarm characterization in hyperspectral gas-detection applications

    Science.gov (United States)

    DiPietro, Robert S.; Truslow, Eric; Manolakis, Dimitris G.; Golowich, Steven E.; Lockwood, Ronald B.

    2012-09-01

    Chemical cloud detection using long-wave infrared (LWIR) hyperspectral-imaging sensors has many civilian and military applications, including chemical warfare threat mitigation, environmental monitoring, and emergency response. Current capabilities are limited by variation in background clutter as opposed to the physics of photon detection, and this makes the statistical characterization of clutter and clutter-induced false alarms essential to the design of practical systems. In this exploratory work, we use hyperspectral data collected both on the ground and in the air to spectrally and spatially characterize false alarms. Focusing on two widely-used detectors, the matched filter (MF) and the adaptive cosine estimator (ACE), we compare empirical false-alarm rates to their theoretical counterparts - detector output under Gaussian, t and t-mixture distributed data - and show that these models often underestimate false-alarm rates. Next, we threshold real detection maps and show that true detections and false alarms often exhibit very different spatial behavior. To exploit this difference and understand how spatial processing affects performance, the spatial behavior of false alarms must be understood. We take a first step in this direction by showing that, although the behavior may `look' quite random, it is not well captured by the complete-spatial-randomness model. Finally, we describe how our findings impact the design of real detection systems.

  1. Microfabricated Chemical Sensors for Aerospace Fire Detection Applications

    Science.gov (United States)

    Hunter, Gary W.; Neudeck, Philip G.; Fralick, Gustave; Thomas, Valarie; Makel, D.; Liu, C. C.; Ward, B.; Wu, Q. H.

    2001-01-01

    The detection of fires on-board commercial aircraft is extremely important for safety reasons. Although dependable fire detection equipment presently exists within the cabin, detection of fire within the cargo hold has been less reliable and susceptible to false alarms. A second, independent method of fire detection to complement the conventional smoke detection techniques, such as the measurement of chemical species indicative of a fire, will help reduce false alarms and improve aircraft safety. Although many chemical species are indicative of a fire, two species of particular interest are CO and CO2. This paper discusses microfabricated chemical sensor development tailored to meet the needs of fire safety applications. This development is based on progress in three types of technology: 1) Micromachining and microfabrication (Microsystem) technology to fabricate miniaturized sensors. 2) The use of nanocrystalline materials to develop sensors with improved stability combined with higher sensitivity. 3) The development of high temperature semiconductors, especially silicon carbide. The individual sensor being developed and their level of maturity will be presented.

  2. Minimizing antibody cross-reactivity in multiplex detection of biomarkers in paper-based point-of-care assays

    Science.gov (United States)

    Dias, J. T.; Lama, L.; Gantelius, J.; Andersson-Svahn, H.

    2016-04-01

    Highly multiplexed immunoassays could allow convenient screening of hundreds or thousands of protein biomarkers simultaneously in a clinical sample such as serum or plasma, potentially allowing improved diagnostic accuracy and clinical management of many conditions such as autoimmune disorders, infections, and several cancers. Currently, antibody microarray-based tests are limited in part due to cross reactivity from detection antibody reagents. Here we present a strategy that reduces the cross-reactivity between nanoparticle-bound reporter antibodies through the application of ultrasound energy. By this concept, it was possible to achieve a sensitivity 103-fold (5 pg mL-1) lower than when no ultrasound was applied (50 ng mL-1) for the simultaneous detection of three different antigens. The detection limits and variability achieved with this technique rival those obtained with other types of multiplex sandwich assays.Highly multiplexed immunoassays could allow convenient screening of hundreds or thousands of protein biomarkers simultaneously in a clinical sample such as serum or plasma, potentially allowing improved diagnostic accuracy and clinical management of many conditions such as autoimmune disorders, infections, and several cancers. Currently, antibody microarray-based tests are limited in part due to cross reactivity from detection antibody reagents. Here we present a strategy that reduces the cross-reactivity between nanoparticle-bound reporter antibodies through the application of ultrasound energy. By this concept, it was possible to achieve a sensitivity 103-fold (5 pg mL-1) lower than when no ultrasound was applied (50 ng mL-1) for the simultaneous detection of three different antigens. The detection limits and variability achieved with this technique rival those obtained with other types of multiplex sandwich assays. Electronic supplementary information (ESI) available. See DOI: 10.1039/c5nr09207h

  3. Performance metrics for point target detection in consecutive frame IR imagery

    Science.gov (United States)

    Silverman, Jerry; Caefer, Charlene E.; Mooney, Jonathan M.

    1995-09-01

    In the companion paper, two algorithms for tracking point targets in consecutive frame staring IR imagery with evolving cloud clutter are described and compared by using representative example scenes. Here, our total data base of local airborne scenes with targets of opportunity are used for a more quantitative and comprehensive comparison. The use of real world data as well as our focus on temporal filtering over large number of consecutive frames triggered a search for more relevant metrics than those available. We present two new metrics which have most of the attributes sought. In each metric, gain is taken as a ratio of output to input signal to clutter. Maximum values rather than statistical measures are used for clutter. In the variation metric (VM), a temporal standard deviation for each pixel over 95 consecutive frames is computed and the maximum non-target result is taken as the input clutter. The input signal, a real target moving with sub-pixel velocity through sampled imagery, is estimated by a reference mean technique. Output signal and clutter are taken as maximum target and clutter affected pixels in algorithm filtered outputs. In the second metric, the use of an anti-median filter (AM) provides symmetric treatment of input and output as well as signal and clutter. The maximum target and non-target response to the AM filter on input frames and output frames defines the signal and clutter measures. Our set of real-world data is plotted as output versus input signal to clutter for each metric and each algorithm and the pros and cons of each metric is discussed. With either metric, the signal to clutter gain ratios are approximately 5 - 6 dB greater with the temporal filter algorithm than with the velocity filter algorithm.

  4. Detection of the Deformation of an Intelligent Textile in a Specific Point

    Science.gov (United States)

    Alsina, Maria; Escudero, Francesc; Margalef, Jordi; Cambra, Vicente; Gisbert, José

    2007-01-01

    An intelligent textile is a textile structure that measures and reacts in front of external agents or stimulus with or without integrated electronic equipment. The finality of the present textile is to take one more step towards intelligent textile, considering the integration of electronics and textile needs, to be industrially viable and to keep up the necessary competitiveness, raising the final price as little as possible. The finality of these experiments is to develop a textile that varies in conductivity and resistance in relation to the elongation of the textile, detecting changes caused by the alteration of a piece of clothing, from the pressure of a finger on the material, for example. One of the most important characteristics of textile is the capacity of reproducing measures, of varying the response in different tests. Two lines of research were opened: the study of the most adequate structure to achieve a response that can be reproduced and the study of the best way of taking measures without altering the behavior of the textile.

  5. Detection of the Deformation of an Intelligent Textile in a Specific Point

    Directory of Open Access Journals (Sweden)

    José Gisbert

    2007-06-01

    Full Text Available An intelligent textile is a textile structure that measures and reacts in front of external agents or stimulus with or without integrated electronic equipment. . The finality of the present textile is to take one more step towards intelligent textile, considering the integration of electronics and textile needs, to be industrially viable and to keep up the necessary competitiveness, raising the final price as little as possible. The finality of these experiments is to develop a textile that varies in conductivity and resistance in relation to the elongation of the textile, detecting changes caused by the alteration of a piece of clothing, from the pressure of a finger on the material, for example. One of the most important characteristics of textile is the capacity of reproducing measures, of varying the response in different tests. Two lines of research were opened: the study of the most adequate structure to achieve a response that can be reproduced and the study of the best way of taking measures without altering the behavior of the textile.

  6. Singularity detection by wavelet approach: application to electrocardiogram signal

    Science.gov (United States)

    Jalil, Bushra; Beya, Ouadi; Fauvet, Eric; Laligant, Olivier

    2010-01-01

    In signal processing, the region of abrupt changes contains the most of the useful information about the nature of the signal. The region or the points where these changes occurred are often termed as singular point or singular region. The singularity is considered to be an important character of the signal, as it refers to the discontinuity and interruption present in the signal and the main purpose of the detection of such singular point is to identify the existence, location and size of those singularities. Electrocardiogram (ECG) signal is used to analyze the cardiovascular activity in the human body. However the presence of noise due to several reasons limits the doctor's decision and prevents accurate identification of different pathologies. In this work we attempt to analyze the ECG signal with energy based approach and some heuristic methods to segment and identify different signatures inside the signal. ECG signal has been initially denoised by empirical wavelet shrinkage approach based on Steins Unbiased Risk Estimate (SURE). At the second stage, the ECG signal has been analyzed by Mallat approach based on modulus maximas and Lipschitz exponent computation. The results from both approaches has been discussed and important aspects has been highlighted. In order to evaluate the algorithm, the analysis has been done on MIT-BIH Arrhythmia database; a set of ECG data records sampled at a rate of 360 Hz with 11 bit resolution over a 10mv range. The results have been examined and approved by medical doctors.

  7. Microfluidic Surface Plasmon Resonance Sensors: From Principles to Point-of-Care Applications.

    Science.gov (United States)

    Wang, Da-Shin; Fan, Shih-Kang

    2016-01-01

    Surface plasmon resonance (SPR) is a label-free, highly-sensitive, and real-time sensing technique. Conventional SPR sensors, which involve a planar thin gold film, have been widely exploited in biosensing; various miniaturized formats have been devised for portability purposes. Another type of SPR sensor which utilizes localized SPR (LSPR), is based on metal nanostructures with surface plasmon modes at the structural interface. The resonance condition is sensitive to the refractive index change of the local medium. The principles of these two types of SPR sensors are reviewed and their integration with microfluidic platforms is described. Further applications of microfluidic SPR sensors to point-of-care (POC) diagnostics are discussed. PMID:27472340

  8. Maximum Power Point Tracking of Photovoltaic System for Traffic Light Application

    Directory of Open Access Journals (Sweden)

    Riza Muhida

    2013-07-01

    Full Text Available Photovoltaic traffic light system is a significant application of renewable energy source. The development of the system is an alternative effort of local authority to reduce expenditure for paying fees to power supplier which the power comes from conventional energy source. Since photovoltaic (PV modules still have relatively low conversion efficiency, an alternative control of maximum power point tracking (MPPT method is applied to the traffic light system. MPPT is intended to catch up the maximum power at daytime in order to charge the battery at the maximum rate in which the power from the battery is intended to be used at night time or cloudy day. MPPT is actually a DC-DC converter that can step up or down voltage in order to achieve the maximum power using Pulse Width Modulation (PWM control. From experiment, we obtained the voltage of operation using MPPT is at 16.454 V, this value has error of 2.6%, if we compared with maximum power point voltage of PV module that is 16.9 V. Based on this result it can be said that this MPPT control works successfully to deliver the power from PV module to battery maximally.

  9. Optimal Spectral Regions For Laser Excited Fluorescence Diagnostics For Point Of Care Application

    Science.gov (United States)

    Vaitkuviene, A.; Gėgžna, V.; Varanius, D.; Vaitkus, J.

    2011-09-01

    The tissue fluorescence gives the response of light emitting molecule signature, and characterizes the cell composition and peculiarities of metabolism. Both are useful for the biomedical diagnostics, as reported in previous our and others works. The present work demonstrates the results of application of laser excited autofluorescence for diagnostics of pathology in genital tissues, and the feasibility for the bedside at "point of care—off lab" application. A portable device using the USB spectrophotometer, micro laser (355 nm Nd:YAG, 0,5 ns pulse, repetition rate 10 kHz, output power 15 mW), three channel optical fiber and computer with diagnostic program was designed and ready for clinical trial to be used for cytology and biopsy specimen on site diagnostics, and for the endoscopy/puncture procedures. The biopsy and cytology samples, as well as intervertebral disc specimen were evaluated by pathology experts and the fluorescence spectra were investigated in the fresh and preserved specimens. The spectra were recorded in the spectral range 350-900 nm. At the initial stage the Gaussian components of spectra were found and the Mann-Whitney test was used for the groups' differentiation and the spectral regions for optimal diagnostics purpose were found. Then a formal dividing of spectra in the components or the definite width bands, where the main difference of the different group spectra was observed, was used to compare these groups. The ROC analysis based diagnostic algorithms were created for medical prognosis. The positive prognostic values and negative prediction values were determined for cervical Liquid PAP smear supernatant sediment diagnosis of being Cervicitis and Norma versus CIN2+. In a case of intervertebral disc the analysis allows to get the additional information about the disc degeneration status. All these results demonstrated an efficiency of the proposed procedure and the designed device could be tested at the point-of-care site or for

  10. Ground Control Point - Wireless System Network for UAV-based environmental monitoring applications

    Science.gov (United States)

    Mejia-Aguilar, Abraham

    2016-04-01

    In recent years, Unmanned Aerial Vehicles (UAV) have seen widespread civil applications including usage for survey and monitoring services in areas such as agriculture, construction and civil engineering, private surveillance and reconnaissance services and cultural heritage management. Most aerial monitoring services require the integration of information acquired during the flight (such as imagery) with ground-based information (such as GPS information or others) for improved ground truth validation. For example, to obtain an accurate 3D and Digital Elevation Model based on aerial imagery, it is necessary to include ground-based information of coordinate points, which are normally acquired with surveying methods based on Global Position Systems (GPS). However, GPS surveys are very time consuming and especially for longer time series of monitoring data repeated GPS surveys are necessary. In order to improve speed of data collection and integration, this work presents an autonomous system based on Waspmote technologies build on single nodes interlinked in a Wireless Sensor Network (WSN) star-topology for ground based information collection and later integration with surveying data obtained by UAV. Nodes are designed to be visible from the air, to resist extreme weather conditions with low-power consumption. Besides, nodes are equipped with GPS as well as Inertial Measurement Unit (IMU), accelerometer, temperature and soil moisture sensors and thus provide significant advantages in a broad range of applications for environmental monitoring. For our purpose, the WSN transmits the environmental data with 3G/GPRS to a database on a regular time basis. This project provides a detailed case study and implementation of a Ground Control Point System Network for UAV-based vegetation monitoring of dry mountain grassland in the Matsch valley, Italy.

  11. Detection of thin current sheets and associated reconnection in the Earth's turbulent magnetosheath using cluster multi-point measurements

    Science.gov (United States)

    Chasapis, Alexandros; Retino, Alessandro; Sahraoui, Fouad; Greco, Antonella; Vaivads, Andris; Sundkvist, David; Canu, Patrick

    2013-04-01

    Magnetic reconnection occurs in turbulent plasma within a large number of volume-filling thin current sheets and is one major candidate for energy dissipation of turbulent plasma. Such dissipation results in particle heating and non-thermal particle acceleration. In situ observations are needed to study the detailed properties of thin current sheets and associated reconnection, in order to determine its importance as a dissipation mechanism at small scales. In particular, multi-point measurements are crucial to unambiguously identify spatial scales (e.g current sheet thickness) and estimate key quantities such as E*J. Here we present a study of the properties of thin current sheets detected in the Earths magnetosheath downstream of the quasi-parallel shock by using Cluster spacecraft data. The current sheets were detected by the rotation of the magnetic field as computed by four-point measurements. We study the distribution of current sheets as a function of the magnetic shear angle θ, their duration and the waiting time between consecutive current sheets. We found that high shear (θ > 90 degrees) current sheets show different properties with respect to low shear current sheets (θ PVI) and we discuss the results of such comparison.

  12. Development of Outlier detection Algorithm Applicable to a Korean Surge-Gauge

    Science.gov (United States)

    Lee, Jun-Whan; Park, Sun-Cheon; Lee, Won-Jin; Lee, Duk Kee

    2016-04-01

    The Korea Meteorological Administration (KMA) is operating a surge-gauge (aerial ultrasonic type) at Ulleung-do to monitor tsunamis. And the National Institute of Meteorological Sciences (NIMS), KMA is developing a tsunami detection and observation system using this surge-gauge. Outliers resulting from a problem with the transmission and extreme events, which change the water level temporarily, are one of the most common discouraging problems in tsunami detection. Unlike a spike, multipoint outliers are difficult to detect clearly. Most of the previous studies used statistic values or signal processing methods such as wavelet transform and filter to detect the multipoint outliers, and used a continuous dataset. However, as the focus moved to a near real-time operation with a dataset that contains gaps, these methods are no longer tenable. In this study, we developed an outlier detection algorithm applicable to the Ulleung-do surge gauge where both multipoint outliers and missing data exist. Although only 9-point data and two arithmetic operations (plus and minus) are used, because of the newly developed keeping method, the algorithm is not only simple and fast but also effective in a non-continuous dataset. We calibrated 17 thresholds and conducted performance tests using the three month data from the Ulleung-do surge gauge. The results show that the newly developed despiking algorithm performs reliably in alleviating the outlier detecting problem.

  13. Bio-Aerosol Detection Using Mass Spectrometry: Public Health Applications

    Energy Technology Data Exchange (ETDEWEB)

    Ludvigson, L D

    2004-03-05

    I recently spent a summer as an intern at the Lawrence Livermore National Laboratory. I worked on a project involving the real-time, reagentless, single cell detection of aerosolized pathogens using a novel mass spectrometry approach called Bio-Aerosol Mass Spectrometry (BAMS). Based upon preliminary results showing the differentiation capabilities of BAMS, I would like to explore the development and use of this novel detection system in the context of both environmental and clinical sample pathogen detection. I would also like to explore the broader public health applications that a system such as BAMS might have in terms of infectious disease prevention and control. In order to appreciate the potential of this instrument, I will demonstrate the need for better pathogen detection methods, and outline the instrumentation, data analysis and preliminary results that lead me toward a desire to explore this technology further. I will also discuss potential experiments for the future along with possible problems that may be encountered along the way.

  14. High mobility ZnO nanowires for terahertz detection applications

    Science.gov (United States)

    Liu, Huiqiang; Peng, Rufang; Chu, Sheng; Chu, Shijin

    2014-07-01

    An oxide nanowire material was utilized for terahertz detection purpose. High quality ZnO nanowires were synthesized and field-effect transistors were fabricated. Electrical transport measurements demonstrated the nanowire with good transfer characteristics and fairly high electron mobility. It is shown that ZnO nanowires can be used as building blocks for the realization of terahertz detectors based on a one-dimensional plasmon detection configuration. Clear terahertz wave (˜0.3 THz) induced photovoltages were obtained at room temperature with varying incidence intensities. Further analysis showed that the terahertz photoresponse is closely related to the high electron mobility of the ZnO nanowire sample, which suggests that oxide nanoelectronics may find useful terahertz applications.

  15. High mobility ZnO nanowires for terahertz detection applications

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Huiqiang [State Key Laboratory of Optoelectronic Materials and Technology, Sun Yat-Sen University, Guangdong, Guangzhou 510275 (China); State Key Laboratory Cultivation Base for Nonmetal Composites and Functional Materials, Southwest University of Science and Technology, Sichuan, Mianyang 621010 (China); Peng, Rufang, E-mail: pengrufang@swust.edu.cn, E-mail: chusheng@mail.sysu.edu.cn; Chu, Shijin [State Key Laboratory Cultivation Base for Nonmetal Composites and Functional Materials, Southwest University of Science and Technology, Sichuan, Mianyang 621010 (China); Chu, Sheng, E-mail: pengrufang@swust.edu.cn, E-mail: chusheng@mail.sysu.edu.cn [State Key Laboratory of Optoelectronic Materials and Technology, Sun Yat-Sen University, Guangdong, Guangzhou 510275 (China)

    2014-07-28

    An oxide nanowire material was utilized for terahertz detection purpose. High quality ZnO nanowires were synthesized and field-effect transistors were fabricated. Electrical transport measurements demonstrated the nanowire with good transfer characteristics and fairly high electron mobility. It is shown that ZnO nanowires can be used as building blocks for the realization of terahertz detectors based on a one-dimensional plasmon detection configuration. Clear terahertz wave (∼0.3 THz) induced photovoltages were obtained at room temperature with varying incidence intensities. Further analysis showed that the terahertz photoresponse is closely related to the high electron mobility of the ZnO nanowire sample, which suggests that oxide nanoelectronics may find useful terahertz applications.

  16. An application of decentralized estimation in a fault detection problem

    Directory of Open Access Journals (Sweden)

    Tadić Predrag R.

    2009-01-01

    Full Text Available This paper presents a design of a decentralized fault detection and isolation (FDI filter by means of an overlapping decentralized estimation algorithm based on a consensus strategy. An efficient solution to the FDI problem can be obtained by an adequate system decomposition into overlapping subsystems and the construction of local FDI estimators aimed at achieving the desired performance. The general aspects and properties of a consensus based estimator are described in the first part of the paper. An applicability of such an estimator to an FDI problem in a large scale system is discussed next. Namely, a case study related to the detection of fire dissymmetry in a thermal power plant boiler is presented, including the process description and identification procedure, comparison between the results obtained by local and decentralized estimators and conclusions concerning their validity.

  17. Generation and Detection of Infrared Single Photons and their Applications

    Institute of Scientific and Technical Information of China (English)

    ZENG He-ping; WU Guang; WU E; PAN Hai-feng; ZHOU Chun-yuan; WU E.,F.Treussart; J.-F.Roch

    2006-01-01

    Unbreakable secret communication has been a dream from ancient time.It is quantum physics that gives us hope to turn this wizardly dream into reality.The rapid development of quantum cryptography may put an end to the history of eavesdropping.This will be largely due to the advanced techniques related to single quanta,especially infrared single photons.In this paper,we report on our research works on single-photon control for quantum cryptography,ranging from single-photon generation to single-photon detection and their applications.

  18. Solid state nuclear track detection : theory and applications

    International Nuclear Information System (INIS)

    Solid state nuclear track detection (SSNTD) technique is simple and inexpensive in nature. The two main steps involved in SSNTD are the formation of latent tracks and their subsequent development (visualisation) by chemical or other means. These are discussed in detail. Applications of SSNTD in the fields of nuclear physics, dosimetry, biology and for determination of contents of an element and its spatial distribution are described. The monograph is intended to serve both beginners and specialists. It also gives a list of simple experiments that can be conveniently introduced at the undergraduate/postgraduate level. (M.G.B.). 20 refs., 8 figs., 3 tabs

  19. Detection of the Security Vulnerabilities in Web Applications

    Directory of Open Access Journals (Sweden)

    2009-01-01

    Full Text Available The contemporary organizations develop business processes in a very complex environment. The IT&C technologies are used by organizations to improve their competitive advantages. But, the IT&C technologies are not perfect. They are developed in an iterative process and their quality is the result of the lifecycle activities. The audit and evaluation processes are required by the increased complexity of the business processes supported by IT&C technologies. In order to organize and develop a high-quality audit process, the evaluation team must analyze the risks, threats and vulnerabilities of the information system. The paper highlights the security vulnerabilities in web applications and the processes of their detection. The web applications are used as IT&C tools to support the distributed information processes. They are a major component of the distributed information systems. The audit and evaluation processes are carried out in accordance with the international standards developed for information system security assurance.

  20. APPLICATION OF A MODEL OF ASSESSMENT FOR DETECTION OF FOOD WASTE IN SCHOOL CANTEENS: AN OPPORTUNITY TO MONITOR SEVERAL FOOD RISK FACTORS

    OpenAIRE

    S Saccares; V. Morena; R. Condoleo; S. Marozzi; A. Ermenegildi; Se Saccares; Scognamiglio, U.

    2012-01-01

    Application of a model for detection of food waste, applied within a school canteen, allows to make different assessments on critical points encountered in the service. The detection system can complete the HACCP path and provide useful guidance for official control Services, involved in food safety.

  1. Processing 3D flash LADAR point-clouds in real-time for flight applications

    Science.gov (United States)

    Craig, R.; Gravseth, I.; Earhart, R. P.; Bladt, J.; Barnhill, S.; Ruppert, L.; Centamore, C.

    2007-04-01

    Ball Aerospace & Technologies Corp. has demonstrated real-time processing of 3D imaging LADAR point-cloud data to produce the industry's first time-of-flight (TOF) 3D video capability. This capability is uniquely suited to the rigorous demands of space and airborne flight applications and holds great promise in the area of autonomous navigation. It will provide long-range, three dimensional video information to autonomous flight software or pilots for immediate use in rendezvous and docking, proximity operations, landing, surface vision systems, and automatic target recognition and tracking. This is enabled by our new generation of FPGA based "pixel-tube" processors, coprocessors and their associated algorithms which have led to a number of advancements in high-speed wavefront processing along with additional advances in dynamic camera control, and space laser designs based on Ball's CALIPSO LIDAR. This evolution in LADAR is made possible by moving the mechanical complexity required for a scanning system into the electronics, where production, integration, testing and life-cycle costs can be significantly reduced. This technique requires a state of the art TOF read-out integrated circuit (ROIC) attached to a sensor array to collect high resolution temporal data, which is then processed through FPGAs. The number of calculations required to process the data is greatly reduced thanks to the fact that all points are captured at the same time and thus correlated. This correlation allows extremely efficient FPGA processing. This capability has been demonstrated in prototype form at both Marshal Space Flight Center and Langley Research Center on targets that represent docking and landing scenarios. This report outlines many aspects of this work as well as aspects of our recent testing at Marshall's Flight Robotics Laboratory.

  2. Application of covert illumination to intrusion surveillance, assessment, and detection

    Science.gov (United States)

    Maki, Melvin C.; Scherbarth, Stefan

    1995-05-01

    Covert illumination is an important element in providing surveillance, detection, and assessment for security applications. IR illumination is increasingly providing this function; however, conventional filament-based illuminators have limited performance and life. A new variety of light emitting diode (LED) illuminators is described that provides long life at low power. A further advance is to use a planar array of LED's with lenses to optimize the uniformity of scene illumination and maximize the illumination range. Modern CCD cameras have an inherently high IR sensitivity so are well matched to work with this illumination. Further enhancements are to integrate the combination of low-light camera and LED illuminator in a discrete column type package to make the overall illumination and assessment system unobtrusive. Finally, these components can be further combined with automated assessment aids to turn the surveillance device into a true detection sensor that can operate stand-alone without active personnel monitoring. A review of the major IR design considerations is included, along with several examples of systems to illustrate potential applications.

  3. Detecting groundwater discharge dynamics from point to catchment scale in a lowland stream: combining hydraulic and tracer methods

    Directory of Open Access Journals (Sweden)

    J. B. Poulsen

    2014-12-01

    Full Text Available Detecting, quantifying, and understanding groundwater discharge to streams are crucial for the assessment of water, nutrient and contaminant exchange at the surface water–groundwater interface. In lowland agricultural catchments with significant groundwater discharge this is of particular importance because of the risk of excess leaching of nutrients to streams. Here we aim to combine hydraulic and tracer methods from point to catchment scale to assess the temporal and spatial variability of groundwater discharge in a lowland, groundwater gaining stream in Denmark. At the point scale groundwater fluxes to the stream were quantified based on Vertical streambed Temperature Profiles (VTP. At the reach scale (0.15–2 km the spatial distribution of zones of focused groundwater discharge was investigated by the use of Distributed Temperature Sensing (DTS. Groundwater discharge to the stream was quantified using differential gauging with an Acoustic Doppler Current Profiler (ADCP. At the catchment scale (26–114 km2 runoff sources during main rain events were investigated by hydrograph separations based on Electrical Conductivity (EC and stable isotopes 2H / 1H. Clear differences in runoff sources between catchments were detected, ranging from approximately 65% event water for the most responsive sub-catchment and less than 10% event water for the least responsive sub-catchment. This shows a large variability in groundwater discharge to the stream, despite the similar lowland characteristics of sub-catchments, indicating the usefulness of environmental tracers for obtaining information about integrated catchment functioning during events. There were also clear spatial patterns of focused groundwater discharge detected by the DTS and ADCP measurements at the reach scale suggesting high spatial variability, where a significant part of groundwater discharge was concentrated in few zones indicating the possibility of concentrated nutrient or pollutant

  4. A Review of Lawsuits Related to Point-of-Care Emergency Ultrasound Applications

    Directory of Open Access Journals (Sweden)

    Stolz, Lori

    2014-12-01

    Full Text Available Introduction: New medical technology brings the potential of lawsuits related to the usage of that new technology. In recent years the use of point-of-care (POC ultrasound has increased rapidly in the emergency department (ED. POC ultrasound creates potential legal risk to an emergency physician (EP either using or not using this tool. The aim of this study was to quantify and characterize reported decisions in lawsuits related to EPs performing POC ultrasound. Methods: We conducted a retrospective review of all United States reported state and federal cases in the Westlaw database. We assessed the full text of reported cases between January 2008 and December 2012. EPs with emergency ultrasound fellowship training reviewed the full text of each case. Cases were included if an EP was named, the patient encounter was in the emergency department, the interpretation or failure to perform an ultrasound was a central issue and the application was within the American College of Emergency Physician (ACEP ultrasound core applications. In order to assess deferred risk, cases that involved ultrasound examinations that could have been performed by an EP but were deferred to radiology were included. Results: We identified five cases. All reported decisions alleged a failure to perform an ultrasound study or a failure to perform it in a timely manner. All studies were within the scope of emergency medicine and were ACEP emergency ultrasound core applications. A majority of cases (n=4 resulted in a patient death. There were no reported cases of failure to interpret or misdiagnoses. Conclusion: In a five-year period from January 2008 through December 2012, five malpractice cases involving EPs and ultrasound examinations that are ACEP core emergency ultrasound applications were documented in the Westlaw database. All cases were related to failure to perform an ultrasound study or failure to perform a study in a timely manner and none involved failure to

  5. Quantum cascade laser: Applications in chemical detection and environmental monitoring

    Directory of Open Access Journals (Sweden)

    Radovanović Jelena

    2009-01-01

    Full Text Available In this paper we consider the structural parameter optimization of the active region of a GaAs-based quantum cascade laser in order to maximize the optical gain of the laser at the characteristic wavelengths, which are best suited for detection of pollutant gasses, such as SO2, HNO3, CH4, and NH3, in the ambient air by means of direct absorption. The procedure relies on applying elaborate tools for global optimization, such as the genetic algorithm. One of the important goals is to extend the applicability of a single active region design to the detection of several compounds absorbing at close wave-lengths, and this is achieved by introducing a strong external magnetic field perpendicularly to the epitaxial layers. The field causes two-dimensional continuous energy subbands to split into the series of discrete Landau levels. Since the arrangement of Landau levels depends strongly on the magnitude of the magnetic field, this enables one to control the population inversion in the active region, and hence the optical gain. Furthermore, strong effects of band non-parabolicity result in subtle changes of the lasing wavelength at magnetic fields which maximize the gain, thus providing a path for fine-tuning of the output radiation properties and changing the target compound for detection. The numerical results are presented for quantum cascade laser structures designed to emit at specified wavelengths in the mid-infrared part of the spectrum.

  6. Quantum cascade laser: applications in chemical detection and environmental monitoring

    International Nuclear Information System (INIS)

    In this paper we consider the structural parameter optimization of the active region of a GaAs-based quantum cascade laser in order to maximize the optical gain of the laser at the characteristic wavelengths, which are best suited for detection of pollutant gasses, such as SO2, HNO3, CH4, and NH3, in the ambient air by means of direct absorption. The procedure relies on applying elaborate tools for global optimization, such as the genetic algorithm. One of the important goals is to extend the applicability of a single active region design to the detection of several compounds absorbing at close wavelengths, and this is achieved by introducing a strong external magnetic field perpendicularly to the epitaxial layers. The field causes two-dimensional continuous energy subbands to split into the series of discrete Landau levels. Since the arrangement of Landau levels depends strongly on the magnitude of the magnetic field, this enables one to control the population inversion in the active region, and hence the optical gain. Furthermore, strong effects of band non-parabolicity result in subtle changes of the lasing wavelength at magnetic fields which maximize the gain, thus providing a path for fine-tuning of the output radiation properties and changing the target compound for detection. The numerical results are presented for quantum cascade laser structures designed to emit at specified wavelengths in the mid-infrared part of the spectrum. (author)

  7. Detection and extraction of signals from the epoch of reionization using higher order one-point statistics

    CERN Document Server

    Harker, Geraint J A; Thomas, Rajat M; Jelic, Vibor; Labropoulos, Panagiotis; Mellema, Garrelt; Iliev, Ilian T; Bernardi, Gianni; Brentjens, Michiel A; De Bruyn, A G; Ciardi, Benedetta; Koopmans, Leon V E; Pandey, V N; Pawlik, Andreas H; Schaye, Joop; Yatawatta, Sarod

    2008-01-01

    Detecting redshifted 21cm emission from neutral hydrogen in the early Universe promises to give direct constraints on the epoch of reionization (EoR). It will, though, be very challenging to extract the cosmological signal from foregrounds and noise which are orders of magnitude larger. Fortunately, the signal has some characteristics which differentiate it from the foregrounds and noise, and we suggest that using the correct statistics may tease out signatures of reionization. We generate mock datacubes simulating the output of the LOFAR EoR experiment. These cubes combine realistic models for Galactic and extragalactic foregrounds and the noise with three different simulations of the cosmological signal. We fit out the foregrounds, which are smooth in the frequency direction, to produce residual images in each frequency band. We denoise these images and study the skewness of the one-point distribution in the images as a function of frequency. We find that, under sufficiently optimistic assumptions, we can r...

  8. Evaluation of Optical Detection Platforms for Multiplexed Detection of Proteins and the Need for Point-of-Care Biosensors for Clinical Use

    Directory of Open Access Journals (Sweden)

    Samantha Spindel

    2014-11-01

    Full Text Available This review investigates optical sensor platforms for protein multiplexing, the ability to analyze multiple analytes simultaneously. Multiplexing is becoming increasingly important for clinical needs because disease and therapeutic response often involve the interplay between a variety of complex biological networks encompassing multiple, rather than single, proteins. Multiplexing is generally achieved through one of two routes, either through spatial separation on a surface (different wells or spots or with the use of unique identifiers/labels (such as spectral separation—different colored dyes, or unique beads—size or color. The strengths and weaknesses of conventional platforms such as immunoassays and new platforms involving protein arrays and lab-on-a-chip technology, including commercially-available devices, are discussed. Three major public health concerns are identified whereby detecting medically-relevant markers using Point-of-Care (POC multiplex assays could potentially allow for a more efficient diagnosis and treatment of diseases.

  9. Free Shape Context Descriptors Optimized with Genetic Algorithm for the Detection of Dead Tree Trunks in ALS Point Clouds

    Science.gov (United States)

    Polewski, P.; Yao, W.; Heurich, M.; Krzystek, P.; Stilla, U.

    2015-08-01

    In this paper, a new family of shape descriptors called Free Shape Contexts (FSC) is introduced to generalize the existing 3D Shape Contexts. The FSC introduces more degrees of freedom than its predecessor by allowing the level of complexity to vary between its parts. Also, each part of the FSC has an associated activity state which controls whether the part can contribute a feature value. We describe a method of evolving the FSC parameters for the purpose of creating highly discriminative features suitable for detecting specific objects in sparse point clouds. The evolutionary process is built on a genetic algorithm (GA) which optimizes the parameters with respect to cross-validated overall classification accuracy. The GA manipulates both the structure of the FSC and the activity flags, allowing it to perform an implicit feature selection alongside the structure optimization by turning off segments which do not augment the discriminative capabilities. We apply the proposed descriptor to the problem of detecting single standing dead tree trunks from ALS point clouds. The experiment, carried out on a set of 285 objects, reveals that an FSC optimized through a GA with manually tuned recombination parameters is able to attain a classification accuracy of 84.2%, yielding an increase of 4.2 pp compared to features derived from eigenvalues of the 3D covariance matrix. Also, we address the issue of automatically tuning the GA recombination metaparameters. For this purpose, a fuzzy logic controller (FLC) which dynamically adjusts the magnitude of the recombination effects is co-evolved with the FSC parameters in a two-tier evolution scheme. We find that it is possible to obtain an FLC which retains the classification accuracy of the manually tuned variant, thereby limiting the need for guessing the appropriate meta-parameter values.

  10. Application of Data Cubes for Improving Detection of Water Cycle Extreme Events

    Science.gov (United States)

    Albayrak, Arif; Teng, William

    2015-01-01

    As part of an ongoing NASA-funded project to remove a longstanding barrier to accessing NASA data (i.e., accessing archived time-step array data as point-time series), for the hydrology and other point-time series-oriented communities, "data cubes" are created from which time series files (aka "data rods") are generated on-the-fly and made available as Web services from the Goddard Earth Sciences Data and Information Services Center (GES DISC). Data cubes are data as archived rearranged into spatio-temporal matrices, which allow for easy access to the data, both spatially and temporally. A data cube is a specific case of the general optimal strategy of reorganizing data to match the desired means of access. The gain from such reorganization is greater the larger the data set. As a use case of our project, we are leveraging existing software to explore the application of the data cubes concept to machine learning, for the purpose of detecting water cycle extreme events, a specific case of anomaly detection, requiring time series data. We investigate the use of support vector machines (SVM) for anomaly classification. We show an example of detection of water cycle extreme events, using data from the Tropical Rainfall Measuring Mission (TRMM).

  11. Application of TruScreen in detecting ASCUS patients

    Institute of Scientific and Technical Information of China (English)

    Weihong Li; Yu Guo; Haiyan Niu; Song Jin; Li Wang

    2011-01-01

    Objective:To explore the application of cervical cancer screening system, TruScreen in detecting atypical squamous cell of undetermined significance(ASCUS) patients.Methods: A total of42 cases were selected, who were diagnosed asASCUSby thinprep cytologic test(TCT). Area from site15 to20, site21 to32 were detected by TruScreen. And the result was compared with those of cases which had positive pathological result of cervical biopsy.Results:There were 16 cases with abnormal pathological result inASCUS cases, including 6 cases with cervical intraepithelial neoplasia(CIN) Ⅰ,6 cases withCINⅡ,3 cases withCINⅢ and 1 case with infiltrating carcinoma. The consistency betweenTCT and pathological test was38.10% (16/42). The positive rate of TruScreen at site15-20 was 61.91% (26/42). There was significant difference in consistency with pathological test betweenTCT and TruScreen (x2=4.762,P=0.029). The positive rate of TruScreen at site21-32 was66.67% (28/42)(Kappa=0.181,P=0.016). There was significant difference in consistency with pathological test betweenTCT and TruScreen(x2=9.4919,P=0.002).And no case was missed when site 21-32 of patients withCIN栻 and above were detected by TruScreen. Conclusions:TruScreen is effective in detectingASCUS patients.

  12. A Canonical Ensemble Approach to the Fermion/Boson Random Point Processes and its Applications

    OpenAIRE

    Tamura, H.; Ito, K. R.

    2005-01-01

    We introduce the boson and the fermion point processes from the elementary quantum mechanical point of view. That is, we consider quantum statistical mechanics of canonical ensemble for a fixed number of particles which obey Bose-Einstein, Fermi-Dirac statistics, respectively, in a finite volume. Focusing on the distribution of positions of the particles, we have point processes of the fixed number of points in a bounded domain. By taking the thermodynamic limit such that the particle density...

  13. A Canonical Ensemble Approach to the Fermion/Boson Random Point Processes and Its Applications

    OpenAIRE

    Tamura, Hiroshi; Ito, Keiichi R.

    2006-01-01

    We introduce the boson and the fermion point processes from the elementary quantum mechanical point of view. That is, we consider quantum statistical mechanics of the canonical ensemble for a fixed number of particles which obey Bose-Einstein, Fermi-Dirac statistics, respectively, in a finite volume. Focusing on the distribution of positions of the particles, we have point processes of the fixed number of points in a bounded domain. By taking the thermodynamic limit such that the particle den...

  14. Multi-point flicker recognition apparatus and its application for video display terminal work.

    Directory of Open Access Journals (Sweden)

    Yunoki,Emiko

    1987-02-01

    Full Text Available The apparatus to measure multi-point critical flicker fusion frequency (MCFF was devised for more precise determination of the critical flicker fusion frequency (CFF. Using this apparatus, the variations in flicker value after the work load of the television (TV game, the Kraepelin using the video display terminal (VDT-Kraepelin and the paper-Kraepelin were examined in order to test its practical applicability. The following results were obtained. The degree of decrease in the CFF values of some peripheral eye fields was larger than that on the central field of both eyes (ordinary CFF after work load. The variation rates of the central and the peripheral flicker values were measured before and after loading in each work, and the correlations of variation rates between two CFF values among them were calculated. The numbers of peripheral eye fields showing significant correlation of variation rates between two eye fields in the TV game and the VDT-Kraepelin, were greater than those in the paper-Kraepelin.

  15. Application of fuzzy logic to optimize placement of an acquisition, tracking, and pointing experiment

    Science.gov (United States)

    Bukley, Jerry

    The experiment is comprised of a 115,000 cubic meter helium balloon which lifts a 2,900 kg Acquisition, Tracking and Pointing (ATP) experiment package to an altitude of 26 km. The Phillips Laboratory High Altitude Balloon Experiment (HABE) has been developed as a cost-effective means of testing satellite ATP technologies in an environment similar to space. A major advantage of the concept is the flexibility in placement and timing afforded a balloon over a satellite. This flexibility allows HABE to engage targets-of-opportunity launched from the domestic ranges without requiring a dedicated or closely coordinated launch time. The placement of HABE is optimized to maximize active track time. A routine was developed to raster scan the mathematical model of a flight corridor while accumulating the intervals of continuous engagement that satisfy a list of ten rules. Although successful, this method is unable to place priorities or make trades based on the relative importance of the rules. The use of fuzzy logic in the form of approximate reasoning to evaluate the rules, while also considering goals, enables key qualitative considerations to be factored into the overall evaluation. This paper describes the application of fuzzy logic to data analysis and compares the results to conventional Boolean techniques.

  16. Clinical Impact of Time-of-Flight and Point Response Modeling in PET Reconstructions: A Lesion Detection Study

    Science.gov (United States)

    Schaefferkoetter, Joshua; Casey, Michael; Townsend, David; Fakhri, Georges El

    2013-01-01

    Time-of-flight (TOF) and point spread function (PSF) modeling have been shown to improve PET reconstructions, but the impact on physicians in the clinical setting has not been thoroughly investigated. A lesion detection and localization study was performed using simulated lesions in real patient images. Four reconstruction schemes were considered: ordinary Poisson OSEM (OP) alone and combined with TOF, PSF, and TOF+PSF. The images were presented to physicians experienced in reading PET images, and the performance of each was quantified using localization receiver operating characteristic (LROC). Numerical observers (non-prewhitening and Hotelling) were used to identify optimal reconstruction parameters, and observer SNR was compared to the performance of the physicians. The numerical models showed good agreement with human performance, and best performance was achieved by both when using TOF+PSF. These findings suggest a large potential benefit of TOF+PSF for oncology PET studies, especially in the detection of small, low-intensity, focal disease in larger patients. PMID:23403399

  17. Context-dependent detection of non-linearly distributed points for vegetation classification in airborne LiDAR

    Science.gov (United States)

    Horvat, Denis; Žalik, Borut; Mongus, Domen

    2016-06-01

    This paper proposes a new method for the detection of vegetation in LiDAR data. As vegetation points are characterised by non-linear distributions, they are efficiently recognised based-on large errors obtained when applying the local fitting of planar surfaces. In addition, three contextual filters are introduced capable of dealing with those exceptions that do not conform with previous interpretations. Namely, they are designed for detecting overgrowing vegetation, small objects attached to the planar surfaces (such as balconies, chimneys, and noise within the buildings) and small objects that do not belong to vegetation (vehicles, statues, fences). During the validation, the proposed method achieved over 97% correctness as well as completeness of vegetation recognition in rural areas while its average accuracy in urban settings was 90.7% in terms of F 1 -scores. The method uses only three input parameters and allows for efficient compensation between completeness and correctness, without significantly affecting the F 1 -score. Sensitivity analysis of the method also confirmed the robustness against a sub-optimal definition of the input parameters.

  18. Application of flaw detection methods for detection of fatigue processes in low-alloyed steel

    Directory of Open Access Journals (Sweden)

    Zbigniew H. śUREK

    2007-01-01

    Full Text Available The paper presents the investigations conducted in the Fraunhofer Institute (IZFP Saarbrücken by use of a BEMI microscope (BEMI= Barkhausenrausch- und Wirbelstrom-Mikroskopie or Barkhausen Noise and Eddy Current Microscopy. The ability to detect cyclic and contact fatigue load influences has been investigated. The measurement amplitudes obtained with Barkhausen Noise and Eddy Current probes havebeen analysed. Correlation of measurement results and material’s condition has been observed in case of the eddy current mode method for frequencies above 2 MHz (for contact-loaded material samples. Detection of material’s fatigue process (at 80 % fatiguelife in the sample subjected to series of high-cyclic loads has been proven to be practically impossible. Application of flaw detection methods in material fatigue tests requires modification of test methods and use of investigation methods relevant to physical parameters of the investigated material. The magnetic leakage field method, which has been abandoned by many researchers, may be of significant use in the material fatigue assessment and may provide new research prospects.

  19. Membrane-based, sedimentation-assisted plasma separator for point-of-care applications.

    Science.gov (United States)

    Liu, Changchun; Mauk, Michael; Gross, Robert; Bushman, Frederic D; Edelstein, Paul H; Collman, Ronald G; Bau, Haim H

    2013-11-01

    Often, high-sensitivity, point-of-care (POC) clinical tests, such as HIV viral load, require large volumes of plasma. Although centrifuges are ubiquitously used in clinical laboratories to separate plasma from whole blood, centrifugation is generally inappropriate for on-site testing. Suitable alternatives are not readily available to separate the relatively large volumes of plasma from milliliters of blood that may be needed to meet stringent limit-of-detection specifications for low-abundance target molecules. We report on a simple-to-use, low-cost, pump-free, membrane-based, sedimentation-assisted plasma separator capable of separating a relatively large volume of plasma from undiluted whole blood within minutes. This plasma separator consists of an asymmetric, porous, polysulfone membrane housed in a disposable chamber. The separation process takes advantage of both gravitational sedimentation of blood cells and size exclusion-based filtration. The plasma separator demonstrated a "blood in-plasma out" capability, consistently extracting 275 ± 33.5 μL of plasma from 1.8 mL of undiluted whole blood within less than 7 min. The device was used to separate plasma laden with HIV viruses from HIV virus-spiked whole blood with recovery efficiencies of 95.5% ± 3.5%, 88.0% ± 9.5%, and 81.5% ± 12.1% for viral loads of 35,000, 3500, and 350 copies/mL, respectively. The separation process is self-terminating to prevent excessive hemolysis. The HIV-laden plasma was then injected into our custom-made microfluidic chip for nucleic acid testing and was successfully subjected to reverse-transcriptase loop-mediated isothermal amplification (RT-LAMP), demonstrating that the plasma is sufficiently pure to support high-efficiency nucleic acid amplification. PMID:24099566

  20. Application of fluorescent tracer agent technology to point-of-care gastrointestinal permeability measurement

    Science.gov (United States)

    Dorshow, Richard B.; Shieh, Jeng-Jong; Rogers, Thomas E.; Hall-Moore, Carla; Shaikh, Nurmohammad; Talcott, Michael; Tarr, Phillip I.

    2016-03-01

    Gut dysfunction, often accompanied by increased mucosal permeability to gut contents, frequently accompanies a variety of human intestinal inflammatory conditions. These disorders include inflammatory bowel diseases (e.g., Crohn's Disease) and environmental enteropathy and enteric dysfunction, a condition strongly associated with childhood malnutrition and stunting in resource poor areas of the world. The most widely used diagnostic assay for gastrointestinal permeability is the lactulose to mannitol ratio (L:M) measurement. These sugars are administered orally, differentially absorbed by the gut, and then cleared from the body by glomerular filtration in the kidney. The amount of each sugar excreted in the urine is measured. The larger sugar, lactulose, is minimally absorbed through a healthy gut. The smaller sugar, mannitol, in contrast, is readily absorbed through both a healthy and injured gut. Thus a higher ratio of lactulose to mannitol reflects increased intestinal permeability. However, several issues prevent widespread use of the L:M ratio in clinical practice. Urine needs to be collected over time intervals of several hours, the specimen then needs to be transported to an analytical laboratory, and sophisticated equipment is required to measure the concentration of each sugar in the urine. In this presentation we show that fluorescent tracer agents with molecular weights similar to those of the sugars, selected from our portfolio of biocompatible renally cleared fluorophores, mimic the L:M ratio test for gut permeability. This fluorescent tracer agent detection technology can be used to overcome the limitations of the L:M assay, and is amenable to point-of-care clinical use.

  1. Mapping ground surface deformation using temporarily coherent point SAR interferometry: Application to Los Angeles Basin

    Science.gov (United States)

    Zhang, L.; Lu, Zhiming; Ding, X.; Jung, H.-S.; Feng, G.; Lee, C.-W.

    2012-01-01

    Multi-temporal interferometric synthetic aperture radar (InSAR) is an effective tool to detect long-term seismotectonic motions by reducing the atmospheric artifacts, thereby providing more precise deformation signal. The commonly used approaches such as persistent scatterer InSAR (PSInSAR) and small baseline subset (SBAS) algorithms need to resolve the phase ambiguities in interferogram stacks either by searching a predefined solution space or by sparse phase unwrapping methods; however the efficiency and the success of phase unwrapping cannot be guaranteed. We present here an alternative approach - temporarily coherent point (TCP) InSAR (TCPInSAR) - to estimate the long term deformation rate without the need of phase unwrapping. The proposed approach has a series of innovations including TCP identification, TCP network and TCP least squares estimator. We apply the proposed method to the Los Angeles Basin in southern California where structurally active faults are believed capable of generating damaging earthquakes. The analysis is based on 55 interferograms from 32 ERS-1/2 images acquired during Oct. 1995 and Dec. 2000. To evaluate the performance of TCPInSAR on a small set of observations, a test with half of interferometric pairs is also performed. The retrieved TCPInSAR measurements have been validated by a comparison with GPS observations from Southern California Integrated GPS Network. Our result presents a similar deformation pattern as shown in past InSAR studies but with a smaller average standard deviation (4.6. mm) compared with GPS observations, indicating that TCPInSAR is a promising alternative for efficiently mapping ground deformation even from a relatively smaller set of interferograms. ?? 2011.

  2. Application of clan member signal method in structural damage detection

    Institute of Scientific and Technical Information of China (English)

    Guo Xun; B.F. Spencer; Lu Shunan

    2007-01-01

    It is well known that in most cases, a reference is necessary for structural health diagnosis, and it is very difficult to obtain such a reference for a given structure. In this paper, a clan member signal method (CMSM) is proposed for use in structures consisting of groups (or clans) that have the same geometry, i.e., the same cross section and length, and identical boundary conditions. It is expected that signals measured on any undamaged member in a clan after an event could be used as a reference for any other members in the clan. To verify the applicability of the proposed method, a steel truss model is tested and the results show that the CMSM is very effective in detecting local damage in structures composed of identical slender members.

  3. Clinical applications of gamma-detection probes - radioguided surgery

    Energy Technology Data Exchange (ETDEWEB)

    Schneebaum, S. [Tel Aviv Univ. (Israel). Sackler School of Medicine]|[Tel-Aviv Sourasky Medical Center (Israel). Dept. of Surgery; Even-Sapir, E.; Shacham-Lehrman, H.; Livshitz, G. [Tel-Aviv Sourasky Medical Center (Israel). Dept. of Nuclear Medicine; Cohen, M. [Tel-Aviv Sourasky Medical Center (Israel). Dept. of Plastic Surgery; Gat, A.; Brazovsky, E. [Department of Pathology, Tel-Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv (Israel); Stadler, J. [Tel-Aviv Sourasky Medical Center (Israel). Dept. of Surgery]|[Breast Health Center, Tel-Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv (Israel); Skornick, Y. [Tel-Aviv Sourasky Medical Center (Israel). Dept. of Surgery

    1999-04-01

    Radioguided surgery (RGS) is a surgical technique that enables the surgeon to identify tissue ``marked`` by a radionuclide before surgery, based on the tissue characteristics, the radioactive tracer and its carrying molecule, or the affinity of both. Thus, yet another tool has been added to the inspection and palpation traditionally used by the surgeon. Current clinical applications of radioguided surgery are: radioimmunoguided surgery (RIGS) for colon cancer, sentinel-node mapping for malignant melanoma (which has become state-of-the-art), sentinel-node mapping for breast, vulvar and penile cancer, and detection of parathyroid adenoma and bone tumour (such as osteid osteoma). Although the same gamma-detecting probe (GDP) may be used for all these applications, the carrier substance and the radionuclide differ. MoAb and peptides are used for RIGS, sulphur colloid for sentinel-node mapping, iodine-125 for RIGS, technetium-99m for sentinel node, parathyroid and bone. The mode of injection also differs, but there are some common principles of gamma-guided surgery. RIGS enables the surgeon to corroborate tumour existence, find occult metastases, and assess the margins of resection; this may result in a change on the surgical plan. Sentinel lymph-node (SLN) scintigraphy for melanoma guides the surgeon to find the involved lymph nodes for lymph-node dissection. SLN for breast cancer is being investigated with promising results. This procedure has also changed the outlook of lymph-node pathology by giving the pathologist designated tissue samples for more comprehensive examination. Gamma-guided surgery will result in more accurate and less unnecessary surgery, better pathology and, hopefully, in better patient survival. (orig.) With 10 figs., 3 tabs., 68 refs.

  4. Clinical applications of gamma-detection probes - radioguided surgery

    International Nuclear Information System (INIS)

    Radioguided surgery (RGS) is a surgical technique that enables the surgeon to identify tissue ''marked'' by a radionuclide before surgery, based on the tissue characteristics, the radioactive tracer and its carrying molecule, or the affinity of both. Thus, yet another tool has been added to the inspection and palpation traditionally used by the surgeon. Current clinical applications of radioguided surgery are: radioimmunoguided surgery (RIGS) for colon cancer, sentinel-node mapping for malignant melanoma (which has become state-of-the-art), sentinel-node mapping for breast, vulvar and penile cancer, and detection of parathyroid adenoma and bone tumour (such as osteid osteoma). Although the same gamma-detecting probe (GDP) may be used for all these applications, the carrier substance and the radionuclide differ. MoAb and peptides are used for RIGS, sulphur colloid for sentinel-node mapping, iodine-125 for RIGS, technetium-99m for sentinel node, parathyroid and bone. The mode of injection also differs, but there are some common principles of gamma-guided surgery. RIGS enables the surgeon to corroborate tumour existence, find occult metastases, and assess the margins of resection; this may result in a change on the surgical plan. Sentinel lymph-node (SLN) scintigraphy for melanoma guides the surgeon to find the involved lymph nodes for lymph-node dissection. SLN for breast cancer is being investigated with promising results. This procedure has also changed the outlook of lymph-node pathology by giving the pathologist designated tissue samples for more comprehensive examination. Gamma-guided surgery will result in more accurate and less unnecessary surgery, better pathology and, hopefully, in better patient survival. (orig.)

  5. Error Analysis in a Stereo Vision-Based Pedestrian Detection Sensor for Collision Avoidance Applications

    Directory of Open Access Journals (Sweden)

    David F. Llorca

    2010-04-01

    Full Text Available This paper presents an analytical study of the depth estimation error of a stereo vision-based pedestrian detection sensor for automotive applications such as pedestrian collision avoidance and/or mitigation. The sensor comprises two synchronized and calibrated low-cost cameras. Pedestrians are detected by combining a 3D clustering method with Support Vector Machine-based (SVM classification. The influence of the sensor parameters in the stereo quantization errors is analyzed in detail providing a point of reference for choosing the sensor setup according to the application requirements. The sensor is then validated in real experiments. Collision avoidance maneuvers by steering are carried out by manual driving. A real time kinematic differential global positioning system (RTK-DGPS is used to provide ground truth data corresponding to both the pedestrian and the host vehicle locations. The performed field test provided encouraging results and proved the validity of the proposed sensor for being used in the automotive sector towards applications such as autonomous pedestrian collision avoidance.

  6. Arrival-Time Detection and Ultrasonic Flow-Meter Applications

    Science.gov (United States)

    Willatzen, Morten; Søndergaard, Peter; Latino, Carl; Voss, Frands; Lervad Andersen, Niels; Brokate, Martin; Bounaim, Aicha

    2006-11-01

    The Danfoss problem on ultrasonic flow measurement has been separated into three parts each handled by a subgroup of the authors listed above. The first subgroup deals with a presentation of modelling equations describing the physics of ultrasonic flow meters employing reciprocal ultrasonic transducer systems. The mathematical model presented allows the electrical output signal to be determined corresponding to any time-dependent electrical input signal. The transducers modelled consist of a piezoceramic material layer and a passive acoustic matching layer. The second subgroup analyzes the possibility of coding the input signal so as to simplify arrival-time detection by re.nding the coded input sequence in the received signal. The narrow-band nature of the transducers makes this problem non-trivial but suggestions for improvement are proposed. The analysis given is based on traditional autoand cross-correlation techniques. The third subgroup attempts to improve existing correlation methods in determining arrival-time detection of signals. A mathematical formulation of the problem is given and the application to a set of real signals provided by Danfoss A/S is performed with good results.

  7. Impedimetric DNA detection--steps forward to sensorial application.

    Science.gov (United States)

    Riedel, Marc; Kartchemnik, Julia; Schöning, Michael J; Lisdat, Fred

    2014-08-01

    This study describes a label-free impedimetric sensor based on short ssDNA recognition elements for the detection of hybridization events. We concentrate on the elucidation of the influence of target length and recognition sequence position on the sensorial performance. The impedimetric measurements are performed in the presence of the redox system ferri-/ferrocyanide and show an increase in charge transfer resistance upon hybridization of ssDNA to the sensor surface. Investigations on the impedimetric signal stability demonstrate a clear influence of the buffers used during the sensor preparation and the choice of the passivating mercaptoalcanol compound. A stable sensor system has been developed, enabling a reproducible detection of 25mer target DNA in the low nanomolar range. After hybridization, a sensor regeneration can be reached with deionized water by adjustment of effective convection conditions, ensuring a sensor reusability. By investigations of longer targets with overhangs exposed to the solution, we can demonstrate applicability of the impedimetric detection for longer ssDNA. However, a decreasing charge transfer resistance change (ΔR(ct)) is found by extending the overhang. As a strategy to increase the impedance change for longer target strands, the position of the recognition sequence can be designed in a way that a small overhang is exposed to the electrode surface. This is found to result in an increase in the relative R(ct) change. These results suggest that DNA and consequently negative charge near the electrode possess a larger impact on the impedimetric signal than DNA further away. PMID:24999077

  8. Leakage point detection system for buried gas pipe of dwelling building; Systeme de localisation de fuite concernant les canalisations de gaz souterraines alimentant les batiments residentiels

    Energy Technology Data Exchange (ETDEWEB)

    Mitsunori, Komori [Tokyo Gas Co., Ltd (Japan)

    2000-07-01

    Buried old gas pipes that supply for dwelling buildings are arranged in complicated piping pattern. In case of a gas leakage emergency, it is difficult to locate the leakage point using conventional methods, and it often takes a long time and much effort before repair work can begin. To solve these problems, Tokyo Gas has developed three new types of system: (1)in-pipe stopper system, (2)multi-point leak detection system, and (3)acoustic leakage point detection system. Using these systems, leakage points of buried gas pipes can be located quickly, accurately and cheaply. The three systems are now in use, increasingly the safety and efficiency while reducing the cost of leakage detection work. (authors)

  9. Mobile SIF-application : Cross-platform development of a Xamarin application utilizing data from a SharePoint intranet solution

    OpenAIRE

    Berglind, Raymond; Larsson, Louise

    2016-01-01

    Xamarin, a cross-platform development framework, was used in this project for the development of a proof-of-concept mobile client application for an existing intranet solution. The intranet consists of Microsoft SharePoint components and is a pre-assembled product produced by the requestor of this project; Sogeti. To fetch the intranet’s data, a web API was implemented as an intermediary between the mobile application and the intranet. The Xamarin application targets three different mobile pl...

  10. A multi-analyte biosensor for the simultaneous label-free detection of pathogens and biomarkers in point-of-need animal testing.

    Science.gov (United States)

    Ewald, Melanie; Fechner, Peter; Gauglitz, Günter

    2015-05-01

    For the first time, a multi-analyte biosensor platform has been developed using the label-free 1-lambda-reflectometry technique. This platform is the first, which does not use imaging techniques, but is able to perform multi-analyte measurements. It is designed to be portable and cost-effective and therefore allows for point-of-need testing or on-site field-testing with possible applications in diagnostics. This work highlights the application possibilities of this platform in the field of animal testing, but is also relevant and transferable to human diagnostics. The performance of the platform has been evaluated using relevant reference systems like biomarker (C-reactive protein) and serology (anti-Salmonella antibodies) as well as a panel of real samples (animal sera). The comparison of the working range and limit of detection shows no loss of performance transferring the separate assays to the multi-analyte setup. Moreover, the new multi-analyte platform allows for discrimination between sera of animals infected with different Salmonella subtypes. PMID:25772557

  11. The applicability of research on moving cut data-approximate entropy on abrupt climate change detection

    Science.gov (United States)

    Jin, Hongmei; He, Wenping; Liu, Qunqun; Wang, Jinsong; Feng, Guolin

    2016-04-01

    In this study, the performance of moving cut data-approximate entropy (MC-ApEn) to detect abrupt dynamic changes was investigated. Numerical tests in a time series model indicate that the MC-ApEn method is suitable for the detection of abrupt dynamic changes for three types of meteorological data: daily maximum temperature, daily minimum temperature, and daily precipitation. Additionally, the MC-ApEn method was used to detect abrupt climate changes in daily precipitation data from Northwest China and the Pacific Decadal Oscillation (PDO) index. The results show an abrupt dynamic change in precipitation in 1980 and in the PDO index in 1976. The times indicated for the abrupt changes are identical to those from previous results. Application of the analysis to observational data further confirmed the performance of the MC-ApEn method. Moreover, MC-ApEn outperformed the moving t test (MTT) and the moving detrended fluctuation analysis (MDFA) methods for the detection of abrupt dynamic changes in a simulated 1000-point daily precipitation dataset.

  12. The application of statistical pattern recognition methods for damage detection to field data

    International Nuclear Information System (INIS)

    Recent studies in structural health monitoring have shown that damage detection algorithms based on statistical pattern recognition techniques for ambient vibrations can be used to successfully detect damage in simulated models. However, these algorithms have not been tested on full-scale civil structures, because such data are not readily available. A unique opportunity for examining the effectiveness of these algorithms was presented when data were systematically collected from a progressive damage field test on the Z24 bridge in Switzerland. This paper presents the analysis of these data using an autoregressive algorithm for damage detection, localization, and quantification. Although analyses of previously obtained experimental or numerically simulated data have provided consistently positive diagnosis results, field data from the Z24 bridge show that damage is consistently detected, however not well localized or quantified, with the current diagnostic methods. Difficulties with data collection in the field are also revealed, pointing to the need for careful signal conditioning prior to algorithm application. Furthermore, interpretation of the final results is made difficult due to the lack of detailed documentation on the testing procedure

  13. Precise Point Positioning with Ionosphere Estimation and application of Regional Ionospheric Maps

    Science.gov (United States)

    Galera Monico, J. F.; Marques, H. A.; Rocha, G. D. D. C.

    2015-12-01

    The ionosphere is one of most difficult source of errors to be modelled in the GPS positioning, mainly when applying data collected by single frequency receivers. Considering Precise Point Positioning (PPP) with single frequency data the options available include, for example, the use of Klobuchar model or applying Global Ionosphere Maps (GIM). The GIM contains Vertical Electron Content (VTEC) values that are commonly estimated considering a global network with poor covering in certain regions. For this reason Regional Ionosphere Maps (RIM) have been developed considering local GNSS network, for instance, the La Plata Ionospheric Model (LPIM) developed inside the context of SIRGAS (Geocentric Reference System for Americas). The South American RIM are produced with data from nearly 50 GPS ground receivers and considering these maps are generated for each hour with spatial resolution of one degree it is expected to provide better accuracy in GPS positioning for such region. Another possibility to correct for ionosphere effects in the PPP is to apply the ionosphere estimation technique based on Kalman filter. In this case, the ionosphere can be treated as a stochastic process and a good initial guess is necessary what can be obtained from an ionospheric map. In this paper we present the methodology involved with ionosphere estimation by using Kalman filter and also the application of global and regional ionospheric maps in the PPP as first guess. The ionosphere estimation strategy was implemented in the house software called RT_PPP that is capable of accomplishing PPP either for single or dual frequency data. GPS data from Brazilian station near equatorial region were processed and results with regional maps were compared with those by using global maps. Improvements of the order 15% were observed. In case of ionosphere estimation, the estimated coordinates were compared with ionosphere free solution and after PPP convergence the results reached centimeter accuracy.

  14. Orthogonal projection of points in CAD/CAM applications: an overview

    OpenAIRE

    Kwanghee Ko; Takis Sakkalis

    2014-01-01

    This paper aims to review methods for computing orthogonal projection of points onto curves and surfaces, which are given in implicit or parametric form or as point clouds. Special emphasis is place on orthogonal projection onto conics along with reviews on orthogonal projection of points onto curves and surfaces in implicit and parametric form. Except for conics, computation methods are classified into two groups based on the core approaches: iterative and subdivision based. An extension of ...

  15. A Computer Application for Visualization of the Gas Concentration Patterns from Instant Point Source in Fluid Static and Anisotropy Medium

    International Nuclear Information System (INIS)

    The computer application for visualization of the gas concentration patterns the effect from gas leakage for example the pipe leakage of the fuel gas drilling, has been done. The application developed to assist one of the components in environmental control system in industrial area or mining area, I.e. in order to forecasting of an area contaminated the effect from pipe leakage available. The model used of unsteady state diffusion model from instant point source in fluid static and diffusion model from instant point source in anisotropy medium. The gas concentration illustrate to come from pipe leakage source is a Gauss distribution curve. The model of this computer application is simulation model with data input facilities and the simulation result is three and two dimension graph. For developed of the computer program used Matlab 6.1. By varying in inputs, the computer application produces numerous concentration gas predictions as 2-dimension, 3-dimension and contour patterns. (author)

  16. Non-contact measurement of carotid arterial stiffness by two-point heart-pulse laser detection

    Science.gov (United States)

    Benedetti, M.; Favalli, V.; Mariano, A.; Rebrova, N.; Consoli, A.; Ayadi, J.; Gilardi, L.; Perna, M.; Minzioni, P.; Arbustini, E.; Giuliani, G.

    2016-02-01

    Arterial stiffness (AS) is a recognized predictor of cardiovascular risk and mortality, and a potential marker for monitoring the beneficial effects of medical treatments for arterial diseases. AS is typically evaluated indirectly, by assessing the so called pulse wave velocity (PWV), i.e. the speed at which the pressure wave created by the heart contraction travels along the aorta and other arteries. PWV is generally measured using piezoelectric transducers, or via a complex ultrasound technique, but in both cases it requires a direct contact with the patient, which could also modify the measured parameters. In the EU project "NISTAS" (Non-invasive screening of the status of the vascular system) [1], we develop a contactless system allowing to measure the PWV thanks to a technology derived from laser triangulation devices. The measurement principle consists in the detection of the small (around 100μm) displacement of the neck skin, induced by the transit of the pressure wave in the carotid. By simultaneously measuring the displacement caused by the pulse wave in two distinct points along the carotid, the time required by the pressure wave to travel a certain distance can be measured, and the PWV can then be easily calculated. The chosen technique for the skin displacement measurement is laser triangulation in its 2D variant (i.e. "laser profilometry"), which is robust to slight movements of the target, it does not suffer from speckle-pattern signal fading, and it can be conveniently implemented using low-cost optical components. Two light lines, emitted by two blue LEDs are projected on the target (the patient's neck skin), and the skin displacement versus time is measured using a high-frame-rate CMOS camera. In this manuscript we present the results obtained by measuring the PWV of 10 volunteers. It is foreseen that this technique can become a simple and widespread point-of-care method for large-scale cardiovascular system screening over large populations.

  17. Automated shock detection and analysis algorithm for space weather application

    Science.gov (United States)

    Vorotnikov, Vasiliy S.; Smith, Charles W.; Hu, Qiang; Szabo, Adam; Skoug, Ruth M.; Cohen, Christina M. S.

    2008-03-01

    Space weather applications have grown steadily as real-time data have become increasingly available. Numerous industrial applications have arisen with safeguarding of the power distribution grids being a particular interest. NASA uses short-term and long-term space weather predictions in its launch facilities. Researchers studying ionospheric, auroral, and magnetospheric disturbances use real-time space weather services to determine launch times. Commercial airlines, communication companies, and the military use space weather measurements to manage their resources and activities. As the effects of solar transients upon the Earth's environment and society grow with the increasing complexity of technology, better tools are needed to monitor and evaluate the characteristics of the incoming disturbances. A need is for automated shock detection and analysis methods that are applicable to in situ measurements upstream of the Earth. Such tools can provide advance warning of approaching disturbances that have significant space weather impacts. Knowledge of the shock strength and speed can also provide insight into the nature of the approaching solar transient prior to arrival at the magnetopause. We report on efforts to develop a tool that can find and analyze shocks in interplanetary plasma data without operator intervention. This method will run with sufficient speed to be a practical space weather tool providing useful shock information within 1 min of having the necessary data to ground. The ability to run without human intervention frees space weather operators to perform other vital services. We describe ways of handling upstream data that minimize the frequency of false positive alerts while providing the most complete description of approaching disturbances that is reasonably possible.

  18. Plain to point network reduced graphene oxide - activated carbon composites decorated with platinum nanoparticles for urine glucose detection

    Science.gov (United States)

    Hossain, Mohammad Faruk; Park, Jae Y.

    2016-02-01

    In this study, a hydrothermal technique was applied to synthesize glucose-treated reduced graphene oxide-activated carbon (GRGO/AC) composites. Platinum nanoparticles (PtNP) were electrochemically deposited on the modified GRGO/AC surface, and chitosan-glucose oxidase (Chit-GOx) composites and nafion were integrated onto the modified surface of the working electrode to prepare a highly sensitive glucose sensor. The fabricated biosensor exhibited a good amperometric response to glucose in the detection range from 0.002 mM to 10 mM, with a sensitivity of 61.06 μA/mMcm2, a short response time (4 s) and a low detection limit of 2 μM (signal to noise ratio is 3). The glucose sensor exhibited a negligible response to interference and good stability. In addition, the glucose levels in human urine were tested in order to conduct a practical assessment of the proposed sensor, and the results indicate that the sensor had superior urine glucose recognition. These results thus demonstrate that the noble nano-structured electrode with a high surface area and electrocatalytic activity offers great promise for use in urine glucose sensing applications.

  19. Approximate Fixed Point Theorems in Banach Spaces with Applications in Game Theory

    OpenAIRE

    2002-01-01

    In this paper some new approximate fixed point theorems for multifunctions in Banach spaces are presented and a method is developed indicating how to use approximate fixed point theorems in proving the existence of approximate Nash equilibria for non-cooperative games.

  20. OPTIMAL MANAGEMENT OF NON-POINT SOURCE POLLUTION FROM AGRICULTURE: AN APPLICATION OF DYNAMIC PROGRAMMING

    Science.gov (United States)

    Agricultural non-point source pollution is a major source of water quality impairment. When considering responses to non-point source pollution, several policy options have been considered historically, including reducing inputs (e.g. fertilizers) altering technologies on the landscape (e.g. conserv...

  1. Two Propositions on the Application of Point Elasticities to Finite Price Changes.

    Science.gov (United States)

    Daskin, Alan J.

    1992-01-01

    Considers counterintuitive propositions about using point elasticities to estimate quantity changes in response to price changes. Suggests that elasticity increases with price along a linear demand curve, but falling quantity demand offsets it. Argues that point elasticity with finite percentage change in price only approximates percentage change…

  2. Krasnosel’skii Type Hybrid Fixed Point Theorems and Their Applications to Fractional Integral Equations

    Directory of Open Access Journals (Sweden)

    H. M. Srivastava

    2014-01-01

    Full Text Available Some hybrid fixed point theorems of Krasnosel’skii type, which involve product of two operators, are proved in partially ordered normed linear spaces. These hybrid fixed point theorems are then applied to fractional integral equations for proving the existence of solutions under certain monotonicity conditions blending with the existence of the upper or lower solution.

  3. Krasnosel’skii Type Hybrid Fixed Point Theorems and Their Applications to Fractional Integral Equations

    OpenAIRE

    Srivastava, H. M.; Sachin V. Bedre; S.M. Khairnar; Desale, B. S.

    2014-01-01

    Some hybrid fixed point theorems of Krasnosel’skii type, which involve product of two operators, are proved in partially ordered normed linear spaces. These hybrid fixed point theorems are then applied to fractional integral equations for proving the existence of solutions under certain monotonicity conditions blending with the existence of the upper or lower solution.

  4. Singularities and scaling invariants of susceptibility in biasing field near critical point: application to uniaxial ferroelectrics

    International Nuclear Information System (INIS)

    The general shape of the temperature dependence of the static susceptibility in a biasing field conjugated to the order parameter is analysed with the use of the simplest equation of state compatible with the Widom and Griffiths scaling hypothesis. The corresponding curves are demonstrated to show from two to four inflection points, from which a discontinuous inflection point is found to occur exactly at the critical point whenever the critical exponent of susceptibility differs from one: γ≠. The unique inflection point occurring below the temperature of the maximum of the susceptibility in the case of the classical critical exponents, i.e. in the mean field theory, is also shown to be strictly independent of the biasing field. New scaling invariants related to the inflection points are found and their analytical expressions are given for the considered equation of state. The usefulness of the theoretical results to the analysis of experimental data is discussed

  5. Application of a practical method for the isocenter point in vivo dosimetry by a transit signal

    Science.gov (United States)

    Piermattei, Angelo; Fidanzio, Andrea; Azario, Luigi; Grimaldi, Luca; D'Onofrio, Guido; Cilla, Savino; Stimato, Gerardina; Gaudino, Diego; Ramella, Sara; D'Angelillo, Rolando; Cellini, Francesco; Trodella, Lucio; Russo, Aniello; Iadanza, Luciano; Zucca, Sergio; Fusco, Vincenzo; Di Napoli, Nicola; Gambacorta, Maria Antonietta; Balducci, Mario; Cellini, Numa; Deodato, Francesco; Macchia, Gabriella; Morganti, Alessio G.

    2007-08-01

    This work reports the results of the application of a practical method to determine the in vivo dose at the isocenter point, Diso, of brain thorax and pelvic treatments using a transit signal St. The use of a stable detector for the measurement of the signal St (obtained by the x-ray beam transmitted through the patient) reduces many of the disadvantages associated with the use of solid-state detectors positioned on the patient as their periodic recalibration, and their positioning is time consuming. The method makes use of a set of correlation functions, obtained by the ratio between St and the mid-plane dose value, Dm, in standard water-equivalent phantoms, both determined along the beam central axis. The in vivo measurement of Diso required the determination of the water-equivalent thickness of the patient along the beam central axis by the treatment planning system that uses the electron densities supplied by calibrated Hounsfield numbers of the computed tomography scanner. This way it is, therefore, possible to compare Diso with the stated doses, Diso,TPS, generally used by the treatment planning system for the determination of the monitor units. The method was applied in five Italian centers that used beams of 6 MV, 10 MV, 15 MV x-rays and 60Co γ-rays. In particular, in four centers small ion-chambers were positioned below the patient and used for the St measurement. In only one center, the St signals were obtained directly by the central pixels of an EPID (electronic portal imaging device) equipped with commercial software that enabled its use as a stable detector. In the four centers where an ion-chamber was positioned on the EPID, 60 pelvic treatments were followed for two fields, an anterior-posterior or a posterior-anterior irradiation and a lateral-lateral irradiation. Moreover, ten brain tumors were checked for a lateral-lateral irradiation, and five lung tumors carried out with three irradiations with different gantry angles were followed. One center

  6. Application of fixed point theory to chaotic attractors of forced oscillators

    International Nuclear Information System (INIS)

    A review of the structure of chaotic attractors of periodically forced second order nonlinear oscillators suggests that the theory of fixed points of transformations gives information about the fundamental topological structure of attractors. First a simple extension of the Levinson index formula is proved. Then numerical evidence is used to formulate plausible conjectures about absorbing regions containing chaotic attractors in forced oscillators. Applying the Levinson formula suggests a fundamental relation between the number of fixed points or periodic points in a section of the chaotic attractor on the one hand, and a topological invariant of an absorbing region on the other hand. (author)

  7. The application of the pilot points in groundwater numerical inversion model

    Science.gov (United States)

    Hu, Bin; Teng, Yanguo; Cheng, Lirong

    2015-04-01

    Numerical inversion simulation of groundwater has been widely applied in groundwater. Compared to traditional forward modeling, inversion model has more space to study. Zones and inversing modeling cell by cell are conventional methods. Pilot points is a method between them. The traditional inverse modeling method often uses software dividing the model into several zones with a few parameters needed to be inversed. However, distribution is usually too simple for modeler and result of simulation deviation. Inverse cell by cell will get the most actual parameter distribution in theory, but it need computational complexity greatly and quantity of survey data for geological statistical simulation areas. Compared to those methods, pilot points distribute a set of points throughout the different model domains for parameter estimation. Property values are assigned to model cells by Kriging to ensure geological units within the parameters of heterogeneity. It will reduce requirements of simulation area geological statistics and offset the gap between above methods. Pilot points can not only save calculation time, increase fitting degree, but also reduce instability of numerical model caused by numbers of parameters and other advantages. In this paper, we use pilot point in a field which structure formation heterogeneity and hydraulics parameter was unknown. We compare inversion modeling results of zones and pilot point methods. With the method of comparative analysis, we explore the characteristic of pilot point in groundwater inversion model. First, modeler generates an initial spatially correlated field given a geostatistical model by the description of the case site with the software named Groundwater Vistas 6. Defining Kriging to obtain the value of the field functions over the model domain on the basis of their values at measurement and pilot point locations (hydraulic conductivity), then we assign pilot points to the interpolated field which have been divided into 4

  8. Pt@AuNPs integrated quantitative capillary-based biosensors for point-of-care testing application.

    Science.gov (United States)

    Wu, Ze; Fu, Qiangqiang; Yu, Shiting; Sheng, Liangrong; Xu, Meng; Yao, Cuize; Xiao, Wei; Li, Xiuqing; Tang, Yong

    2016-11-15

    Current diagnostic technologies primarily rely on bulky and costly analytical instruments. Therefore, cost-effective and portable diagnosis tools that can be used for point-of-care tests (POCT) are highly desirable. In this study, we report a cost-effective, portable capillary-based biosensor for quantitative detection of biomarkers by the naked eye. This capillary-based biosensor was tested by measuring the distance of blue ink movement, which was directly correlated with the oxygen (O2) produced by efficient core-shell Pt@Au nanoparticles (Pt@AuNPs) catalysts decomposed hydrogen peroxide (H2O2). By linking the Pt@AuNPs with antibodies, capillary-based biosensor sandwich immunoassays were constructed. The concentrations of the target proteins were positively correlated with the distances of ink movement. To demonstrate their performance, the biosensors were used to detect the cancer biomarker sprostate-specific antigen (PSA) and carcinoembryonic antigen (CEA). The linear detection range (LDR) of the capillary-based biosensor for detecting PSA was from 0.02 to 2.5ng/mL, and the limit of detection (LOD) was 0.017ng/mL. LDR of the biosensor for detecting CEA was from 0.063 to 16ng/mL, and the LOD was 0.044ng/mL. For detection of PSA and CEA in clinical serum samples, the detection results of the capillary-based biosensor were well correlate with the results from of chemiluminescence immunoassays (CLIAs). Thus, the capillary-based biosensor may potentially be a useful strategy for point-of-care testing, in addition to being portable and cost effective. PMID:27240013

  9. Fixed points for alpha-psi contractive mappings with an application to quadratic integral equations

    Directory of Open Access Journals (Sweden)

    Bessem Samet

    2014-06-01

    Full Text Available Recently, Samet et al [24] introduced the concept of alpha-psi contractive mappings and studied the existence of fixed points for such mappings. In this article, we prove three fixed point theorems for this class of operators in complete metric spaces. Our results extend the results in [24] and well known fixed point theorems due to Banach, Kannan, Chatterjea, Zamfirescu, Berinde, Suzuki, Ciric, Nieto, Lopez, and many others. We prove that alpha-psi contractions unify large classes of contractive type operators, whose fixed points can be obtained by means of the Picard iteration. Finally, we utilize our results to discuss the existence and uniqueness of solutions to a class of quadratic integral equations.

  10. A random version of Schaefer's fixed point theorem with applications to functional random integral equations

    Directory of Open Access Journals (Sweden)

    B. C. Dhage

    2004-09-01

    Full Text Available In this paper a random version of a fixed-point theorem of Schaefer is obtained and it is further applied to a certain nonlinear functional random integral equation for proving the existence result under Caratheodory conditions.

  11. A Study of Impulsive Multiterm Fractional Differential Equations with Single and Multiple Base Points and Applications

    Directory of Open Access Journals (Sweden)

    Yuji Liu

    2014-01-01

    Full Text Available We discuss the existence and uniqueness of solutions for initial value problems of nonlinear singular multiterm impulsive Caputo type fractional differential equations on the half line. Our study includes the cases for a single base point fractional differential equation as well as multiple base points fractional differential equation. The asymptotic behavior of solutions for the problems is also investigated. We demonstrate the utility of our work by applying the main results to fractional-order logistic models.

  12. Functionalized nanoparticles for biological imaging and detection applications

    Science.gov (United States)

    Mei, Bing C.

    were functionalized using a series of bifunctional ligands that contain a dithiol group (DHLA) for surface binding, a PEG segment to instill water-solubility and a terminal functional group for easy bioconjugation (i.e. NH2, COOH, or biotin). Finally, a sensing application was demonstrated to detect the presence of microbial DNA (unmethlylated CpG) by using Toll-like receptor 9 proteins as the recognition components and the QDs as the transduction elements via Forster Resonance Energy Transfer.

  13. An ethernet/IP security review with intrusion detection applications

    International Nuclear Information System (INIS)

    Supervisory Control and Data Acquisition (SCADA) and automation networks, used throughout utility and manufacturing applications, have their own specific set of operational and security requirements when compared to corporate networks. The modern climate of heightened national security and awareness of terrorist threats has made the security of these systems of prime concern. There is a need to understand the vulnerabilities of these systems and how to monitor and protect them. Ethernet/IP is a member of a family of protocols based on the Control and Information Protocol (CIP). Ethernet/IP allows automation systems to be utilized on and integrated with traditional TCP/IP networks, facilitating integration of these networks with corporate systems and even the Internet. A review of the CIP protocol and the additions Ethernet/IP makes to it has been done to reveal the kind of attacks made possible through the protocol. A set of rules for the SNORT Intrusion Detection software is developed based on the results of the security review. These can be used to monitor, and possibly actively protect, a SCADA or automation network that utilizes Ethernet/IP in its infrastructure. (authors)

  14. Application of Stable Isotope in Detection of Veterinary Drug Residues

    International Nuclear Information System (INIS)

    In recent years, there has happened a series of significant food safety events worldwide, which lower down consumers' confidence in food safety, and they are taking increasing care about the sources of their foods. The safety problem of animal-origin foods has become a global topic for discussion. Therefore, it is a pressing task to establish a precise, sensitive and reliable method for analyzing veterinary drug residue. An introduction of the present status regarding veterinary drug residue analysis was made in the paper, and it briefly summarized the limit of detection (LOD) and quantification (LOQ) which could be reached in veterinary drug residue analysis by isotopic internal standard method domestically and abroad. The paper also made a review of the progress in applied research of stable isotope labeled compound in veterinary drug residue analysis of, such as, antibiotic medicines, furans and sulfonamides. The paper elucidated the great importance of the application of stable isotopes in the sane development of China's food safety system. (authors)

  15. Singularities, swallowtails and Dirac points. An analysis for families of Hamiltonians and applications to wire networks, especially the Gyroid

    Energy Technology Data Exchange (ETDEWEB)

    Kaufmann, Ralph M.; Khlebnikov, Sergei; Wehefritz-Kaufmann, Birgit

    2012-08-15

    Motivated by the Double Gyroid nanowire network we develop methods to detect Dirac points and classify level crossings, aka. singularities in the spectrum of a family of Hamiltonians. The approach we use is singularity theory. Using this language, we obtain a characterization of Dirac points and also show that the branching behavior of the level crossings is given by an unfolding of A{sub n} type singularities. Which type of singularity occurs can be read off a characteristic region inside the miniversal unfolding of an A{sub k} singularity. We then apply these methods in the setting of families of graph Hamiltonians, such as those for wire networks. In the particular case of the Double Gyroid we analytically classify its singularities and show that it has Dirac points. This indicates that nanowire systems of this type should have very special physical properties.

  16. Some Good Reasons to Use Matched Filters for the Detection of Point Sources in CMB Maps (comments on astro-ph/0302245 by Barreiro et al.)

    CERN Document Server

    Vio, R; Wamsteker, W; Vio, Roberto; Andreani, Paola; Wamsteker, Willelm

    2004-01-01

    In this draft we comment on the results concerning the performances of matched filters, scale adaptive filters and Mexican hat wavelet that recently appeared in literature in the context of point source detection in Cosmic Microwave Background maps. In particular, we show that, contrary to what has been claimed, the use of the matched filters still appear to be the most reliable and efficient method to disantangle point sources from the backgrounds, even when using detection criterion that, differently from the classic $n\\sigma$ thresholding rule, takes into account not only the height of the peaks in the signal corresponding to the candidate sources but also their curvature.

  17. Blister pouches for effective reagent storage and release for low cost point-of-care diagnostic applications

    Science.gov (United States)

    Smith, Suzanne; Sewart, Rene; Land, Kevin; Roux, Pieter; Gärtner, Claudia; Becker, Holger

    2016-03-01

    Lab-on-a-chip devices are often applied to point-of-care diagnostic solutions as they are low-cost, compact, disposable, and require only small sample volumes. For such devices, various reagents are required for sample preparation and analysis and, for an integrated solution to be realized, on-chip reagent storage and automated introduction are required. This work describes the implementation and characterization of effective liquid reagent storage and release mechanisms utilizing blister pouches applied to various point-of-care diagnostic device applications. The manufacturing aspects as well as performance parameters are evaluated.

  18. Model Based Fault Detection in a Centrifugal Pump Application

    DEFF Research Database (Denmark)

    Kallesøe, Carsten; Cocquempot, Vincent; Izadi-Zamanabadi, Roozbeh

    2006-01-01

    A model based approach for fault detection in a centrifugal pump, driven by an induction motor, is proposed in this paper. The fault detection algorithm is derived using a combination of structural analysis, observer design and Analytical Redundancy Relation (ARR) design. Structural considerations...... the algorithm is capable of detecting four different faults in the mechanical and hydraulic parts of the pump....

  19. A comparative study of novel spectrophotometric methods based on isosbestic points; application on a pharmaceutical ternary mixture.

    Science.gov (United States)

    Lotfy, Hayam M; Saleh, Sarah S; Hassan, Nagiba Y; Salem, Hesham

    2014-05-21

    This work represents the application of the isosbestic points present in different absorption spectra. Three novel spectrophotometric methods were developed, the first method is the absorption subtraction method (AS) utilizing the isosbestic point in zero-order absorption spectra; the second method is the amplitude modulation method (AM) utilizing the isosbestic point in ratio spectra; and third method is the amplitude summation method (A-Sum) utilizing the isosbestic point in derivative spectra. The three methods were applied for the analysis of the ternary mixture of chloramphenicol (CHL), dexamethasone sodium phosphate (DXM) and tetryzoline hydrochloride (TZH) in eye drops in the presence of benzalkonium chloride as a preservative. The components at the isosbestic point were determined using the corresponding unified regression equation at this point with no need for a complementary method. The obtained results were statistically compared to each other and to that of the developed PLS model. The specificity of the developed methods was investigated by analyzing laboratory prepared mixtures and the combined dosage form. The methods were validated as per ICH guidelines where accuracy, repeatability, inter-day precision and robustness were found to be within the acceptable limits. The results obtained from the proposed methods were statistically compared with official ones where no significant difference was observed. PMID:24589996

  20. Laser-excited fluorescence in fingerprint detection and other criminalistic applications

    Science.gov (United States)

    Menzel, E. R.

    1996-03-01

    An overview of the current and anticipated applications of optical techniques to the detection of latent fingerprints is presented. The focus is on time-resolved approaches. Other criminalistic applications that involve optical technology are taken up briefly.

  1. Topological fixed point theory for singlevalued and multivalued mappings and applications

    CERN Document Server

    Ben Amar, Afif

    2016-01-01

    This is a monograph covering topological fixed point theory for several classes of single and multivalued maps. The authors begin by presenting basic notions in locally convex topological vector spaces. Special attention is then devoted to weak compactness, in particular to the theorems of Eberlein–Šmulian, Grothendick and Dunford–Pettis. Leray–Schauder alternatives and eigenvalue problems for decomposable single-valued nonlinear weakly compact operators in Dunford–Pettis spaces are considered, in addition to some variants of Schauder, Krasnoselskii, Sadovskii, and Leray–Schauder type fixed point theorems for different classes of weakly sequentially continuous operators on general Banach spaces. The authors then proceed with an examination of Sadovskii, Furi–Pera, and Krasnoselskii fixed point theorems and nonlinear Leray–Schauder alternatives in the framework of weak topologies and involving multivalued mappings with weakly sequentially closed graph. These results are formulated in terms of ax...

  2. Modeling and measurement of boiling point elevation during water vaporization from aqueous urea for SCR applications

    Energy Technology Data Exchange (ETDEWEB)

    Dan, Ho Jin; Lee, Joon Sik [Seoul National University, Seoul (Korea, Republic of)

    2016-03-15

    Understanding of water vaporization is the first step to anticipate the conversion process of urea into ammonia in the exhaust stream. As aqueous urea is a mixture and the urea in the mixture acts as a non-volatile solute, its colligative properties should be considered during water vaporization. The elevation of boiling point for urea water solution is measured with respect to urea mole fraction. With the boiling-point elevation relation, a model for water vaporization is proposed underlining the correction of the heat of vaporization of water in the urea water mixture due to the enthalpy of urea dissolution in water. The model is verified by the experiments of water vaporization as well. Finally, the water vaporization model is applied to the water vaporization of aqueous urea droplets. It is shown that urea decomposition can begin before water evaporation finishes due to the boiling-point elevation.

  3. Clinical Application of Shenque (CV 8) plus Eight Battle Points for Obesity

    Institute of Scientific and Technical Information of China (English)

    LIU Xiao-hui; HANG Guo-qi

    2007-01-01

    In order to observe the therapeutic effect of Eight Battle Points for simple obesity.Methods:In the treatment of 98 cases of the patients with obesity by the oblique puncture of long needles into Eight Battle Points,the body weight,body weight index (BWI),waist circumference,buttock circumference and fat distribution rate of the patients were measured and assessed respectively before and after the treatments.And the changes of complications of obesity were observed before and after the treatments.Results:There were significant differences (P<0.05) in various indexes of obesity before and after acupuncture treatment.Conclusion:Acupuncture by puncturing Shenque(CV 8) plus Eight Battle Points is positive in the treatment of obesity and has a better therapeutic effect for complications of obesity.

  4. Real-time attitude commanding to detect coverage gaps and generate high resolution point clouds for RSO shape characterization with a laser rangefinder

    Science.gov (United States)

    Nayak, M.; Beck, J.; Udrea, B.

    This paper expands on previous studies by the authors into 3D imaging with a single-beam laser rangefinder (LRF) by implementing real-time attitude maneuvers of a chaser satellite flying in relative orbit around a resident space object (RSO). Point clouds generated with an LRF are much sparser than those generated with an imaging LIDAR, making it difficult to autonomously distinguish between gaps in coverage and truly empty space. Furthermore, if both the attitude and the shape of the target RSO are unknown, it is particularly difficult to register a collection of LRF strike points together and detect gaps in strike point coverage in realtime. This paper presents the incorporation of a narrow field of-view (NFOV) camera that detects the strike point on the RSO and supplements LRF distance measurements with image data. This data is used to generate attitude command profiles that efficiently fill LRF coverage gaps and generate high density point clouds, thus maximizing coverage of an unknown RSO. Results obtained so far point the way to a real-time implementation of the algorithm. A method to detect and close gaps in LRF strike point coverage is presented first. Coverage gap detection is achieved using Voronoi diagrams, where Voronoi cells are centered at the LRF strike points. A three-part algorithm is used that 1) creates a 3D panoramic map from “ stitched” NFOV camera images; 2) correlates the areas of sparse LRF coverage to the map; and 3) generates attitude commands to close the coverage gaps. The map provides a consistent and reliable method to register positions of strike points relative to each other and to the NFOV image of the RSO without a priori knowledge of the RSO attitude. Using this algorithm, gaps and sparse areas in LRF coverage are covered with strike points, allowing for the generation of a higher-resolution point cloud than that obtained with preprogrammed attitude profiles. Attitude maneuvers can now be designed on-line in real-ti- e such

  5. Combining Areal and Point Data in Geostatistical Interpolation: Applications to Soil Science and Medical Geography.

    Science.gov (United States)

    Goovaerts, Pierre

    2010-07-01

    A common issue in spatial interpolation is the combination of data measured over different spatial supports. For example, information available for mapping disease risk typically includes point data (e.g. patients' and controls' residence) and aggregated data (e.g. socio-demographic and economic attributes recorded at the census track level). Similarly, soil measurements at discrete locations in the field are often supplemented with choropleth maps (e.g. soil or geological maps) that model the spatial distribution of soil attributes as the juxtaposition of polygons (areas) with constant values. This paper presents a general formulation of kriging that allows the combination of both point and areal data through the use of area-to-area, area-to-point, and point-to-point covariances in the kriging system. The procedure is illustrated using two data sets: (1) geological map and heavy metal concentrations recorded in the topsoil of the Swiss Jura, and (2) incidence rates of late-stage breast cancer diagnosis per census tract and location of patient residences for three counties in Michigan. In the second case, the kriging system includes an error variance term derived according to the binomial distribution to account for varying degree of reliability of incidence rates depending on the total number of cases recorded in those tracts. Except under the binomial kriging framework, area-and-point (AAP) kriging ensures the coherence of the prediction so that the average of interpolated values within each mapping unit is equal to the original areal datum. The relationships between binomial kriging, Poisson kriging, and indicator kriging are discussed under different scenarios for the population size and spatial support. Sensitivity analysis demonstrates the smaller smoothing and greater prediction accuracy of the new procedure over ordinary and traditional residual kriging based on the assumption that the local mean is constant within each mapping unit. PMID:21132098

  6. An Analysis of Air Force EOQ Data with an Application to Reorder Point Calculation

    OpenAIRE

    C. R. Mitchell; R. A. Rappold; W. B. Faulkner

    1983-01-01

    One of the important uses of an EOQ item's distribution of lead time demand is to set its reorder point. This paper shows that a realistic model of observed demand patterns can be chosen from the compound Poisson family of distributions. Actual historical data from several U.S. Air Force bases are analyzed using the geometric-Poisson and constant-Poisson distributions. The control discipline is order quantity, reorder point with continuous review. The service level is based on percent of dema...

  7. Some application of the model of partition points on a one-dimensional lattice

    International Nuclear Information System (INIS)

    We have shown that by using a model of the gas of partition points on one-dimensional lattice, we can find some results about the enzyme kinetics or the average domain-size, which we have obtained before by using a correlated Walks' theory or a probabilistic (combinatoric) way. We have discussed also the problem related with the spread of an infection of disease and the stochastic model of partition points. We think that this model, as a very simple model and mathematically transparent, can be advantageous for other theoretical investigations in chemistry or modern biology. (author). 14 refs, 6 figs, 1 tab

  8. Hopfield neural network and its applications on image edge detection

    Institute of Scientific and Technical Information of China (English)

    Yonghong Zhang(张永宏); Dejin Hu(胡德金); Kai Zhang(张凯); Junjie Xu(徐俊杰)

    2004-01-01

    A method of image edge detection using the Hopfield neural network (HNN) is proposed in this paper.The image edge parameters are introduced in detail, and the energy function of HNN is given based on the edge parameters. Tests on the image edge detection show that images detected by the proposed method have good edge closeness and true edge, at the same time it has good anti-noise performance. The image edge detection using HNN is better than that obtained by some other edge detection operators.

  9. A Field Evaluation of the Time-of-Detection Method to Estimate Population Size and Density for Aural Avian Point Counts

    Directory of Open Access Journals (Sweden)

    Mathew W. Alldredge

    2007-12-01

    Full Text Available The time-of-detection method for aural avian point counts is a new method of estimating abundance, allowing for uncertain probability of detection. The method has been specifically designed to allow for variation in singing rates of birds. It involves dividing the time interval of the point count into several subintervals and recording the detection history of the subintervals when each bird sings. The method can be viewed as generating data equivalent to closed capture–recapture information. The method is different from the distance and multiple-observer methods in that it is not required that all the birds sing during the point count. As this method is new and there is some concern as to how well individual birds can be followed, we carried out a field test of the method using simulated known populations of singing birds, using a laptop computer to send signals to audio stations distributed around a point. The system mimics actual aural avian point counts, but also allows us to know the size and spatial distribution of the populations we are sampling. Fifty 8-min point counts (broken into four 2-min intervals using eight species of birds were simulated. Singing rate of an individual bird of a species was simulated following a Markovian process (singing bouts followed by periods of silence, which we felt was more realistic than a truly random process. The main emphasis of our paper is to compare results from species singing at (high and low homogenous rates per interval with those singing at (high and low heterogeneous rates. Population size was estimated accurately for the species simulated, with a high homogeneous probability of singing. Populations of simulated species with lower but homogeneous singing probabilities were somewhat underestimated. Populations of species simulated with heterogeneous singing probabilities were substantially underestimated. Underestimation was caused by both the very low detection probabilities of all distant

  10. Singularities, swallowtails and Dirac points. An analysis for families of Hamiltonians and applications to wire networks, especially the Gyroid

    International Nuclear Information System (INIS)

    Motivated by the Double Gyroid nanowire network we develop methods to detect Dirac points and classify level crossings, aka. singularities in the spectrum of a family of Hamiltonians. The approach we use is singularity theory. Using this language, we obtain a characterization of Dirac points and also show that the branching behavior of the level crossings is given by an unfolding of An type singularities. Which type of singularity occurs can be read off a characteristic region inside the miniversal unfolding of an Ak singularity. We then apply these methods in the setting of families of graph Hamiltonians, such as those for wire networks. In the particular case of the Double Gyroid we analytically classify its singularities and show that it has Dirac points. This indicates that nanowire systems of this type should have very special physical properties. - Highlights: ► New method for analytically finding Dirac points. ► Novel relation of level crossings to singularity theory. ► More precise version of the von-Neumann–Wigner theorem for arbitrary smooth families of Hamiltonians of fixed size. ► Analytical proof of the existence of Dirac points for the Gyroid wire network.

  11. An application of interacting shear flows theory: exact solution for unsteady oblique stagnation point flow

    Institute of Scientific and Technical Information of China (English)

    Guibo Li; Minguo Dai; Zhi Gao

    2006-01-01

    An analytical solution of the governing equations of the interacting shear flows for unsteady oblique stagnation point flow is obtained. It has the same form as that of the exact solution obtained from the complete NS equations and physical analysis and relevant discussions are then presented.

  12. Applications of point vortex equilibria: blocking events and the stability of the polar vortex

    Directory of Open Access Journals (Sweden)

    Annette Müller

    2015-12-01

    Full Text Available The present study investigates non-linear dynamics of atmospheric flow phenomena on different scales as interactions of vortices. Thereby, we apply the idealised, two-dimensional concept of point vortices considering two important issues in atmospheric dynamics. First, we propose this not widely spread concept in meteorology to explain blocked weather situations using a three-point vortex equilibrium. Here, a steady state is given if the zonal mean flow is identical to the opposed translational velocity of the vortex system. We apply this concept exemplarily to two major blocked events establishing a new pattern recognition technique based on the kinematic vorticity number to determine the circulations and positions of the interacting vortices. By using reanalysis data, we demonstrate that the velocity of the tripole in a westward direction is almost equal to the westerly flow explaining the steady state of blocked events. Second, we introduce a novel idea to transfer a stability analysis of a vortex equilibrium to the stability of the polar vortex concerning its interaction with the quasi-biennial oscillation (QBO. Here, the point vortex system is built as a polygon ring of vortices around a central vortex. On this way we confirm observations that perturbations of the polar vortex during the QBO east phase lead to instability, whereas the polar vortex remains stable in QBO west phases. Thus, by applying point vortex theory to challenging problems in atmospheric dynamics we show an alternative, discrete view of synoptic and planetary scale motion.

  13. The opinions of pregnant women about labor and acupressure application who received acupressure on their SP6 points

    OpenAIRE

    Yeşilçiçek Çalık, Kıymet; KÖMÜRCÜ, Nuran

    2014-01-01

    Objective: The research was a randomized controlled study aimed to determine the views regarding acupressure application and labor of the pregnant women who received acupressure on their SP6 acupuncture points during labor. Method: 100 pregnant women, 50 in the experimental group and 50 in the control group, meeting the inclusion criteria were included in the research between July 2009 and April 2010 at Trabzon Maternal Hospital. Pregnancy Identification Forms were administered to the pregnan...

  14. Address Points, Point locations for address sites, including residential, commercial, all units and suites, using Esri's Local Government Information Model schema., Published in 12/1/2014, Not Applicable scale, Gwinnett County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Address Points dataset, published at Not Applicable scale, was produced all or in part from Field Survey/GPS information as of 12/1/2014. It is described as...

  15. Biosignal data preprocessing: a voice pathology detection application

    Directory of Open Access Journals (Sweden)

    Genaro Daza Santacoloma

    2010-05-01

    Full Text Available A methodology for biosignal data preprocessing is presented. Experiments were mainly carried out with voice signals for automa- tically detecting pathologies. The proposed methodology was structured on 3 elements: outlier detection, normality verification and distribution transformation. It improved classification performance if basic assumptions about data structure were met. This entailed a more accurate detection of voice pathologies and it reduced the computational complexity of classification algorithms. Classification performance improved by 15%.

  16. Fiber optic sensor employing successively destroyed coupled points or reflectors for detecting shock wave speed and damage location

    Science.gov (United States)

    Weiss, Jonathan D.

    1995-01-01

    A shock velocity and damage location sensor providing a means of measuring shock speed and damage location. The sensor consists of a long series of time-of-arrival "points" constructed with fiber optics. The fiber optic sensor apparatus measures shock velocity as the fiber sensor is progressively crushed as a shock wave proceeds in a direction along the fiber. The light received by a receiving means changes as time-of-arrival points are destroyed as the sensor is disturbed by the shock. The sensor may comprise a transmitting fiber bent into a series of loops and fused to a receiving fiber at various places, time-of-arrival points, along the receiving fibers length. At the "points" of contact, where a portion of the light leaves the transmitting fiber and enters the receiving fiber, the loops would be required to allow the light to travel backwards through the receiving fiber toward a receiving means. The sensor may also comprise a single optical fiber wherein the time-of-arrival points are comprised of reflection planes distributed along the fibers length. In this configuration, as the shock front proceeds along the fiber it destroys one reflector after another. The output received by a receiving means from this sensor may be a series of downward steps produced as the shock wave destroys one time-of-arrival point after another, or a nonsequential pattern of steps in the event time-of-arrival points are destroyed at any point along the sensor.

  17. Air Conditioning Compressor Air Leak Detection by Image Processing Techniques for Industrial Applications

    Directory of Open Access Journals (Sweden)

    Pookongchai Kritsada

    2015-01-01

    Full Text Available This paper presents method to detect air leakage of an air conditioning compressor using image processing techniques. Quality of air conditioning compressor should not have air leakage. To test an air conditioning compressor leak, air is pumped into a compressor and then submerged into the water tank. If air bubble occurs at surface of the air conditioning compressor, that leakage compressor must be returned for maintenance. In this work a new method to detect leakage and search leakage point with high accuracy, fast, and precise processes was proposed. In a preprocessing procedure to detect the air bubbles, threshold and median filter techniques have been used. Connected component labeling technique is used to detect the air bubbles while blob analysis is searching technique to analyze group of the air bubbles in sequential images. The experiments are tested with proposed algorithm to determine the leakage point of an air conditioning compressor. The location of the leakage point was presented as coordinated point. The results demonstrated that leakage point during process could be accurately detected. The estimation point had error less than 5% compared to the real leakage point.

  18. Non-power application as an entry point to nuclear power program

    International Nuclear Information System (INIS)

    Nuclear power is usually viewed as the flagship of nuclear technology. A nuclear power plant complex, visible and prominence, is iconic of the technology. That image makes its presence common knowledge to the extent that nuclear technology is equated almost totally with nuclear power by the general public. The downside of this visibility is that it becomes easy target in public misinformation programs. The non-power applications however are not visible, and devoid of icon. The non-power applications, therefore, can grow quite smoothly, attracting only little attention in the negative and in the positive senses. According to a study conducted in the USA in 2000 and in Japan in 2002, the socio-economic impact of non-power and power applications of nuclear technology are comparable. Involvement in non-power applications can be a good grounding for moving into power applications. This paper discusses the non-power nuclear technology applications and in what manner it can serve to prepare the introduction of nuclear power program. (Author)

  19. An algorithm for detecting percolating structures in periodic systems - Application to polymer networks

    NARCIS (Netherlands)

    E.A. Koopman; C.P. Lowe

    2014-01-01

    We consider the problem of detecting a percolating structure in an off-lattice model polymer system when periodic boundary conditions are used. Physically, with increasing polymer density, the point at which this first occurs is the gel point. A connected structure spans all space and the system bec

  20. Application of SVM on satellite images to detect hotspots in Jharia coal field region of India

    Energy Technology Data Exchange (ETDEWEB)

    Gautam, R.S.; Singh, D.; Mittal, A.; Sajin, P. [Indian Institute for Technology, Roorkee (India)

    2008-07-01

    The present paper deals with the application of Support Vector Machine (SVM) and image analysis techniques on NOAA/AVHRR satellite image to detect hotspots on the Jharia coal field region of India. One of the major advantages of using these satellite data is that the data are free with very good temporal resolution; while, one drawback is that these have low spatial resolution (i.e., approximately 1.1 km at nadir). Therefore, it is important to do research by applying some efficient optimization techniques along with the image analysis techniques to rectify these drawbacks and use satellite images for efficient hotspot detection and monitoring. For this purpose, SVM and multi-threshold techniques are explored for hotspot detection. The multi-threshold algorithm is developed to remove the cloud coverage from the land coverage. This algorithm also highlights the hotspots or fire spots in the suspected regions. SVM has the advantage over multi-thresholding technique that it can learn patterns from the examples and therefore is used to optimize the performance by removing the false points which are highlighted in the threshold technique. Both approaches can be used separately or in combination depending on the size of the image. The RBF (Radial Basis Function) kernel is used in training of three sets of inputs: brightness temperature of channel 3, Normalized Difference Vegetation Index (NDVI) and Global Environment Monitoring Index (GEMI), respectively. This makes a classified image in the output that highlights the hotspot and non-hotspot pixels. The performance of the SVM is also compared with the performance obtained from the neural networks and SVM appears to detect hotspots more accurately (greater than 91% classification accuracy) with lesser false alarm rate. The results obtained are found to be in good agreement with the ground based observations of the hotspots.