WorldWideScience

Sample records for apparent life-threatening events

  1. Apparent life-threatening event in infancy

    Science.gov (United States)

    Choi, Hee Joung

    2016-01-01

    An apparent life-threatening event (ALTE) is defined as the combination of clinical presentations such as apnea, marked change in skin and muscle tone, gagging, or choking. It is a frightening event, and it predominantly occurs during infancy at a mean age of 1–3 months. The causes of ALTE are categorized into problems that are: gastrointestinal (50%), neurological (30%), respiratory (20%), cardiovascular (5%), metabolic and endocrine (2%–5%), or others such as child abuse. Up to 50% of ALTEs are idiopathic, where the cause cannot be diagnosed. Infants with an ALTE are often asymptomatic at hospital and there is no standard workup protocol for ALTE. Therefore, a detailed initial history and physical examination are important to determine the extent of the medical evaluation and treatment. Regardless of the cause of an ALTE, all infants with an ALTE should require hospitalization and continuous cardiorespiratory monitoring and evaluation for at least 24 hours. The natural course of ALTEs has seemed benign, and the outcome is generally associated with the affected infants' underlying disease. In conclusion, systemic diagnostic evaluation and adequate treatment increases the survival and quality of life for most affected infants.

  2. Infantile Apparent Life-Threatening Events, an Educational Review

    Directory of Open Access Journals (Sweden)

    Hamed Aminiahidashti

    2015-01-01

    Full Text Available Many physicians have received a frantic call from anxious parents stating that their child had stopped breathing, become limp, or turned blue but then had recovered quickly. An apparent life-threatening event (ALTE is defined as “an episode that is frightening to the observer, and is characterized by some combination of apnea, color change, marked change in muscle tone, choking, gagging, or coughing”. The incidence of ALTE is reported to be 0.05% to 6%. The knowledge about the most common causes and factors associated with higher risk of ALTE could be resulted in a more purposeful approach, improving the decision making process, and benefiting both children and parents. The aim of this review article was to report the epidemiology, etiology, evaluation, management, and disposition of ALTE. Infants with an ALTE might present no signs of acute illness and are commonly managed in the emergency settings that often require significant medical attention; hence, the emergency medicine personnel should be aware of the its clinical importance. There is no specific treatment for ALTE; therefore, the clinical evaluations should be focused on the detection of the underlying causes, which will define the outcomes and prognosis. ALTE is a confusing entity, representing a constellation of descriptive symptoms and signs; in other words, it is not a diagnosis. There are multiple possible etiologies and difficulties in evaluating and managing infants with these events, which are challenges to primary care physicians, emergency medicine specialists, and subspecialty pediatricians. The evaluation of these events in infants includes a detailed history, appropriate physical examination, diagnostic tests guided by obtained clues from the history and physical examination, and observation in the emergency department.

  3. [How I EXPLORE ... AN APPARENT LIFE THREATENING EVENT OF THE INFANT].

    Science.gov (United States)

    Zambelli, L; Battisti, O

    2016-04-01

    The ALTE (Apparent Life Threatening Event) of the infant is a frequent presenting complaint. The clinical presentation is varied, ranging from an innocuous event (as a change in skin color) to something as tragic as a sudden infant death. In all circumstances, it is always a very worrying event for the parents and the family circle. Many etiologies can explain the ALTE, and their investigation can be complicated. In this paper, the etiologies and diagnostic tests will be briefly introduced, with a reminder of the sudden infant death syndrome.

  4. OBSERVATION OF MOVEMENTS DURING SLEEP IN ALTE (APPARENT LIFE-THREATENING EVENT) AND APNEIC INFANTS - A PILOT-STUDY

    NARCIS (Netherlands)

    EINSPIELER, C; PRECHTL, HFR; VANEYKERN, L; DEROOS, B

    1994-01-01

    Fourteen infants of 2 months or 6 months of age were video-recorded during polysomnography. Four were normal infants, five had a history of ALTE (apparent life threatening event) and five had repeated and prolonged apnoea during sleep. Two ALTE infants have been recorded at 2 months as well as at 6

  5. Evento com aparente risco de morte: uma revisão Evento con aparente riesgo de muerte (alte: una revisión Apparent life-threatening event: a review

    Directory of Open Access Journals (Sweden)

    Mariana Tresoldi das N. Romaneli

    2012-12-01

    Full Text Available OBJETIVO: Realizar uma revisão crítica reunindo informações disponíveis a respeito dos eventos com aparente risco de morte. FONTES DE DADOS: Revisão bibliográfica dos artigos (em português, inglês e espanhol obtidos dos bancos de dados eletrônicos Medline, Lilacs e SciELO, utilizando as palavras-chave: eventos com aparente risco de morte, evento com aparente risco de vida infantil, lactente, apneia, monitorização e cianose. SÍNTESE DOS DADOS: Os eventos com aparente risco de mortesão súbitos e caracterizados por uma combinação de apneia, alteração na coloração da pele e tônus muscular, com inúmeras causas subjacentes. Sua incidência verdadeira é desconhecida e a faixa etária mais acometida é de 11 a 12 semanas. Não há correlação entre o evento com aparente risco de morte e a síndrome da morte súbita do lactente, embora já tenham sido consideradas manifestações da mesma doença. Muitas vezes, o lactente tem aparência saudável ao ser avaliado pelo pediatra após apresentar eventos com aparente risco de morte, porém, isso não afasta a possibilidade de existir uma doença grave associada ao evento, que deve ser investigada e tratada. Quando não são encontradas as causas, o evento é idiopático, geralmente com boa evolução. CONCLUSÕES: É necessário investigar os lactentes levados ao pronto-socorro após apresentarem eventos com aparente risco de morte, devido ao risco de sequelas e mortalidade. Não há uma padronização das condutas a serem realizadas diante de um lactente com aparência saudável que tenha evento com aparente risco de morte, mas recomenda-se que o paciente seja internado e a causa do evento, investigada. A observação e o monitoramento em ambiente hospitalar devem ocorrer no mínimo 24 horas após o evento.OBJETIVO: Realizar una revisión crítica, reuniendo las informaciones disponibles respecto a los Eventos con Aparente Riesgo de Muerte (ALTE - Apparent life-threatening event

  6. Evento com aparente risco de morte recorrente como manifestação inicial de síndrome miastênica congênita Evento con aparente riesgo de muerte recurrente como manifestación inicial de síndrome miasténico congénito Recurrent apparent life-threatening event as the first manifestation of congenital myasthenia

    Directory of Open Access Journals (Sweden)

    Mariana Tresoldi das N. Romaneli

    2013-03-01

    miastenia congénita. Después de la confirmación del diagnóstico, se mantuvo el tratamiento ambulatorial con piridostigmina, con recuperación nutricional y neurológica, sin nuevos eventos con aparente riesgo de muerte en los tres años siguientes. COMENTARIOS: La investigación minuciosa de las causas de eventos con aparente riesgo de muerte puede llevar a diagnósticos menos frecuentes que exigen tratamiento específico, como la miastenia congénita.OBJECTIVE: To alert pediatricians about the importance of a careful investigation on recurrent apparent life-threatening events. Reports of the association of these events with congenital myasthenic syndromes were not found. CASE DESCRIPTION: A seven-month-old infant with recurrent apparent life-threatening events was admitted for investigation. During hospital stay, she presented cyanosis and respiratory failure, requiring mechanical ventilation for three days. After clinical improvement, hypotheses of gastroesophageal reflux and pulmonary aspiration were ruled out. The presence of eyelid ptosis, general hypotonia and weak crying led to the suspicion of congenital myasthenia, which was confirmed. Treatment with oral piridostigmine led to neurological and nutritional normalization, without any other apparent life-threatening event during the next three years. COMMENTS: The careful etiological investigation of apparent life-threatening events may lead to rare diagnosis that requires specific treatments, such as congenital myasthenia.

  7. Clinical Characteristics and Mortality of Life-Threatening Events Requiring Cardiopulmonary Resuscitation in Gastrointestinal Endoscopy Units.

    Science.gov (United States)

    Park, Hye Min; Kim, Eun Soo; Lee, Sang Min; Lee, Yoo Jin; Park, Kyung Sik; Cho, Kwang Bum; Kim, Eun Young; Jung, Jin Tae; Kim, Kyeong Ok; Jang, Byung Ik; Jung, Yun Jin; Yang, Chang Hun; Lee, Hyun Seok; Jeon, Seong Woo

    2015-10-01

    Little is known about life-threatening events during gastrointestinal endoscopy (GIE). This study aimed to evaluate the clinical characteristics of emergency conditions requiring cardiopulmonary resuscitation (CPR) in GIE units and to assess the risk factors for mortality in these cases.We retrospectively collected life-threatening cases that occurred in the GIE units of 6 tertiary hospitals from January 2012 to June 2014. Cases were defined as alert calls for resuscitation teams in emergency situations of respiratory failure or cardiac arrest. Demographic data, clinical features, and probable causes were assessed. Factors associated with mortality were elucidated using logistic regression analysis.Among 263,426 endoscopies, 40 cases of CPR (0.015%) occurred during the period (male 67.5%, median age 62 yr). Gastrointestinal bleeding (GIB), such as hematemesis or melena, was the most common indication for endoscopy (55%). The types of clinical situations encountered were as follows: respiratory insufficiency (47.5%), decreased blood pressure (25%), and cardiac arrhythmia (25%). Although most of these conditions were detected during endoscopy (67.5%), one-third of cases (32.5%) were found before or after procedures. The most frequent probable cause of cases was aggravation of underlying diseases (57.5%), such as uncontrolled bleeding or exacerbation of lung disease. Despite efforts to resuscitate, 18 patients (45%) died. GIB was the single independent risk factor for mortality (odds ratio 28.45, 95% confidence interval 1.55-523.33, P = 0.024).Life-threatening situations requiring CPR can occur during endoscopy, even before or after the procedure. Greater attention should be paid while endoscopy is performed for GIB. PMID:26512621

  8. Near-death experiences in non-life-threatening events and coma of different etiologies

    Directory of Open Access Journals (Sweden)

    Vanessa eCharland-Verville

    2014-05-01

    Full Text Available Background: Near death experiences (NDEs are increasingly being reported as a clearly identifiable physiological and psychological reality of clinical significance. However, the definition and causes of the phenomenon as well as the identification of NDE experiencers is still a matter of debate. To date, the most widely used standardized tool to identify and characterize NDEs in research is the Greyson NDE Scale. Using this scale, retrospective and prospective studies have been trying to estimate their incidence in various populations but few studies have tackled to associate the experiences’ intensity and content related to etiology. Methods: This retrospective investigation assessed the most frequently recounted features of self-reported NDEs after a non-life-threatening event (i.e., NDE-like experience or after a pathological coma (i.e., classical NDEs and according to the etiology of the acute brain insult. We also compared our retrospectively acquired data in anoxic coma with historical data from the published literature on prospective post-anoxic studies using the Greyson NDE Scale. Results: From our 190 reports who met the criteria for NDE (i.e., NDE scale total score Conclusions: It appears that real NDEs after coma of different etiologies are similar to NDE-like experiences occurring after non-life threatening events. Subjects reporting NDEs retrospectively tend to have experienced a different content compared to the prospective experiencers

  9. Life-Threatening Adverse Events Following Therapeutic Opioid Administration in Adults: Is Pharmacogenetic Analysis Useful?

    Directory of Open Access Journals (Sweden)

    Parvaz Madadi

    2013-01-01

    Full Text Available BACKGROUND: Systemic approaches are needed to understand how variations in the genes associated with opioid pharmacokinetics and response can be used to predict patient outcome. The application of pharmacogenetic analysis to two cases of life-threatening opioid-induced respiratory depression is presented. The usefulness of genotyping in the context of these cases is discussed.

  10. Evaluation and risk stratification of patients with chest pain in the emergency department. Predictors of life-threatening events.

    Science.gov (United States)

    Zalenski, R J; Shamsa, F; Pede, K J

    1998-08-01

    While assessing chest pain in the emergency department, physicians must first estimate the probability of acute ischemic states in the patient. This first estimate is based on the patient's history, physical examination, and electrocardiogram. Patients who meet the threshold for acute cardiac ischemia are further evaluated to confirm or exclude this diagnosis, while other life-threatening factors are excluded. PMID:9739772

  11. Incidence of death and potentially life-threatening near-miss events in living donor hepatic lobectomy: a world-wide survey.

    Science.gov (United States)

    Cheah, Yee Lee; Simpson, Mary Ann; Pomposelli, James J; Pomfret, Elizabeth A

    2013-05-01

    The incidence of morbidity and mortality after living donor liver transplantation (LDLT) is not well understood because reporting is not standardized and relies on single-center reports. Aborted hepatectomies (AHs) and potentially life-threatening near-miss events (during which a donor's life may be in danger but after which there are no long-term sequelae) are rarely reported. We conducted a worldwide survey of programs performing LDLT to determine the incidence of these events. A survey instrument was sent to 148 programs performing LDLT. The programs were asked to provide donor demographics, case volumes, and information about graft types, operative morbidity and mortality, near-miss events, and AHs. Seventy-one programs (48%), which performed donor hepatectomy 11,553 times and represented 21 countries, completed the survey. The average donor morbidity rate was 24%, with 5 donors (0.04%) requiring transplantation. The donor mortality rate was 0.2% (23/11,553), with the majority of deaths occurring within 60 days, and all but 4 deaths were related to the donation surgery. The incidences of near-miss events and AH were 1.1% and 1.2%, respectively. Program experience did not affect the incidence of donor morbidity or mortality, but near-miss events and AH were more likely in low-volume programs (≤50 LDLT procedures). In conclusion, it appears that independently of program experience, there is a consistent donor mortality rate of 0.2% associated with LDLT donor procedures, yet increased experience is associated with lower rates of AH and near-miss events. Potentially life-threatening near-miss events and AH are underappreciated complications that must be discussed as part of the informed consent process with any potential living liver donor.

  12. Cisplatin chemotherapy (without erythropoietin) and risk of life-threatening thromboembolic events in carcinoma of the uterine cervix: the tip of the iceberg? A review of the literature

    International Nuclear Information System (INIS)

    The risk of severe cardiovascular toxicity, specifically thromboembolic events (TE), in patients with cervical cancer receiving concurrent irradiation and cisplatin chemotherapy is reported to be less than 1% in several large prospective trials. However, the anecdotal risk appears to be far higher. A review of several prospective trials demonstrates no treatment related grade 4 cardiovascular toxicities and only two grade 5 toxicities in 1424 (0.1%) collective patients. A recent publication and our own unpublished experience finds 6 of 128 (4.7%) patients developed grade 4 to 5 cardiovascular (thrombosis/embolism) toxicity. The differenc in incidence of severe or life threatening cardiovascular toxicity of 0.1 versus 4.7% is highly statistically significant (p < 0.00001.) This dramatic difference in incidence of cardiovascular toxicity raises the possibility that cardiovascular toxicities were inadequately reported on the listed prospective trials. For those patients enrolled in prospective trials, we suggest that thromboses should be diligently documented and reported. Only after the true incidence of thromboses is established can we implement appropriate levels of early screening and intervention that may prevent life threatening complications

  13. Mutations in cytoplasmic loops of the KCNQ1 channel and the risk of life-threatening events

    DEFF Research Database (Denmark)

    Barsheshet, Alon; Goldenberg, Ilan; O-Uchi, Jin;

    2012-01-01

    β-Adrenergic stimulation is the main trigger for cardiac events in type 1 long-QT syndrome (LQT1). We evaluated a possible association between ion channel response to β-adrenergic stimulation and clinical response to β-blocker therapy according to mutation location.......β-Adrenergic stimulation is the main trigger for cardiac events in type 1 long-QT syndrome (LQT1). We evaluated a possible association between ion channel response to β-adrenergic stimulation and clinical response to β-blocker therapy according to mutation location....

  14. Engaging Active Bystanders in Mass Casualty Events and Other Life-Threatening Emergencies: A Pilot Training Course Demonstration.

    Science.gov (United States)

    Smith, Tracey O; Baker, Susan D; Roberts, Kathryn; Payne, Skip A

    2016-04-01

    Emerging research indicates the critical role members of the public can play in saving lives and reducing morbidity at the scene in the immediate aftermath of a disaster. It is anticipated that with training, more members of the public will be ready and able to assist should they be present at mass casualty events or other circumstances in which there are serious injuries or potential loss of life. This article describes a training course developed by multiple federal and nonfederal partners aimed at preparing the public to become "active bystanders" followed by a pilot demonstration project conducted by Medical Reserve Corps Units. The outcomes of the project indicated that the training was comprehensive and appropriate for members of the public with little or no first aid knowledge. National availability of the "Becoming an Active Bystander" training course is currently being planned. PMID:26841861

  15. Faces in the face of death: effects of exposure to life-threatening events and mortality salience on facial expression recognition in combat and noncombat military veterans.

    Science.gov (United States)

    Anaki, David; Brezniak, Tamar; Shalom, Liron

    2012-08-01

    Soldiers in war zones often experience life-threatening events that put their lives at stake. The present study examined how these exposures shape soldiers' social behavior, manifested by recognition of facial expressions. In addition, we investigated how explicit awareness of one's eventual death affects sensitivity to facial expressions. Veterans of elite military combat units were exposed to conditions of mortality or pain salience and later requested to label the emotions depicted in threatening and nonthreatening faces. Combat veterans were more accurate than noncombat veterans in identifying threatening expressions, both in mortality or pain salience induction (experiment 1) or under no induction at all (experiment 2). In addition, noncombat veterans primed with mortality salience identified fear expressions more accurately than those primed with pain salience. Finally, mortality salience improved accuracy for nonthreatening expressions for all veterans. The present results demonstrate that fear of death, resulting from exposure to concrete life-endangering perils or from thoughts on human's inevitable death, influences perception of facial expressions, which is critical for successful interpersonal communication. PMID:22866887

  16. Mesenteric vascular occlusion: Comparison of ancillary CT findings between arterial and venous occlusions and independent CT findings suggesting life-threatening events

    International Nuclear Information System (INIS)

    To compare the ancillary CT findings between superior mesenteric artery thromboembolism (SMAT) and superior mesenteric vein thrombosis (SMVT), and to determine the independent CT findings of life-threatening mesenteric occlusion. Our study was approved by the institution review board. We included 43 patients (21 SMAT and 22 SMVT between 1999 and 2008) of their median age of 60.0 years, and retrospectively analyzed their CT scans. Medical records were reviewed for demographics, management, surgical pathology diagnosis, and outcome. We compared CT findings between SMAT and SMVT groups. Multivariate analysis was conducted to determine the independent CT findings of life-threatening mesenteric occlusion. Of 43 patients, 24 had life-threatening mesenteric occlusion. Death related to mesenteric occlusion was 32.6%. A thick bowel wall (p < 0.001), mesenteric edema (p < 0.001), and ascites (p = 0.009) were more frequently associated with SMVT, whereas diminished bowel enhancement (p = 0.003) and paralytic ileus (p = 0.039) were more frequent in SMAT. Diminished bowel enhancement (OR = 20; p = 0.007) and paralytic ileus (OR = 16; p = 0.033) were independent findings suggesting life-threatening mesenteric occlusion. The ancillary CT findings occur with different frequencies in SMAT and SMVT. However, the independent findings indicating life-threatening mesenteric occlusion are diminished bowel wall enhancement and paralytic ileus.

  17. Transgender Youth and Life-Threatening Behaviors

    Science.gov (United States)

    Grossman, Arnold H.; D'Augelli, Anthony R.

    2007-01-01

    Sexual minority status is a key risk factor for suicide among lesbian, gay, and bisexual youth; however, it has not been studied among transgender youth. Fifty-five transgender youth reported on their life-threatening behaviors. Nearly half of the sample reported having seriously thought about taking their lives and one quarter reported suicide…

  18. Life-threatening intrathyroidal parathyroid adenoma

    OpenAIRE

    Dogan, Ugur; Koc, Umit; Mayir, Burhan; Habibi, Mani; Dogan, Berna; Gomceli, Ismail; BULBULLER, Nurullah

    2015-01-01

    Acute primary hyperparathyroidism and parathyroid crisis are characterized by life-threatening hypercalcemia, a rare disorder. A 69-year-old female patient presented at our hospital’s neurology clinic with weakness, nausea, vomiting, depression, and hypercalcemia. Treatment of hypercalcemia resulted in no improvement in neurological symptoms, indicating resistance to treatment. Thyroid ultrasonography and parathyroid scintigraphy revealed hypoechoic nodules in the right lobe, pieces of nodule...

  19. Life threatening illness and hospice care.

    Science.gov (United States)

    Stein, A; Forrest, G C; Woolley, H; Baum, J D

    1989-01-01

    A retrospective study was undertaken of 25 families and their 26 ill children attending the first children's hospice in the United Kingdom. The study examined the family's perceptions of the care offered and the impact of chronic and life threatening illness. Eighteen (72%) of the families felt they had been well supported by the hospice and valued the family like atmosphere, perceiving the staff to be friendly, approachable, and helpful. The actual nature of hospice care, in an environment with other terminally ill children, was, however, considered a drawback for a few families. A number of families still had unmet needs, notably appropriate child minding when away from the hospice. The impact of chronic life threatening illness on the families was substantial. The parents (particularly the mothers), the index children, and their siblings all experienced much higher levels of psychological symptomatology than would have been expected from normal samples. While families felt greatly helped over symptom control, a proportion remained very worried about certain symptoms, particularly breathlessness, seizures, and pain. A high proportion of families were experiencing financial and employment difficulties as a result of their children's illnesses. PMID:2730123

  20. Life-threatening necrotizing myometritis, due to Group A streptococcus - still a life-threatening condition

    DEFF Research Database (Denmark)

    Boie, Sidsel; Krog, Jan; Bor, Isil Pinar

    2015-01-01

    Puerperal infection with Group A streptococcus (GAS) can present with few symptoms and rapidly progress to a life-threatening condition. Often, the infection can be treated with antibiotics. Delay in diagnosis increases risk of sepsis, multiorgan failure, and death. GAS infection is a differential...

  1. Narrative review: Electrocution and life-threatening electrical injuries.

    Science.gov (United States)

    Spies, Christian; Trohman, Richard G

    2006-10-01

    The authors reviewed the mechanisms and pathophysiology of typically encountered electrical injuries by searching English-language publications listed in MEDLINE and reference lists from identified articles. They included relevant retrospective studies, case reports, and review articles published between 1966 and 2005. The authors also searched the Internet for information related to electrocution and life-threatening electrical injuries. They found that familiarity with basic principles of physics elucidates the typical injuries sustained by patients who experience electrical shock. Death due to electrocution occurs frequently. However, patients successfully resuscitated after cardiopulmonary arrest often have a favorable prognosis. Approximately 3000 patients who survive electrical shock are admitted to specialized burn units annually. Patients with serious electrical burns admitted to the intensive care unit are trauma patients and should be treated accordingly. Initial prediction of outcome for patients who have experienced electrical shock is difficult, as the full degree of injury is often not apparent. PMID:17015871

  2. Life-threatening hypernatraemic dehydration in breastfed babies.

    Science.gov (United States)

    Shroff, R; Hignett, R; Pierce, C; Marks, S; van't Hoff, W

    2006-12-01

    We describe five babies, who were exclusively breast fed, with life-threatening complications of hypernatraemic dehydration secondary to inadequate breast feeding. An increased awareness among health professionals is required so that this potentially devastating condition can be prevented.

  3. Happy ending of life-threatening upper GI bleeding

    Science.gov (United States)

    Islam, Quazi Tarikul; Siddiqui, Mahmudur Rahman; Rahman, Md Anisur; Ahmed, Syed Salahuddin

    2011-01-01

    Strongyloides stercoralis is an intestinal nematode in humans, and estimated about tens of millions of people are infected worldwide. This parasite is endemic in tropical or temperate and subtropical climates like Bangladesh. The authors report a 33-year-old man who presented with recurrent life-threatening upper gastrointestinal bleeding from gastric infection by S stercoralis. PMID:22673715

  4. Life-threatening colonic hemorrhage in Crohn's disease: angiographic appearance

    International Nuclear Information System (INIS)

    Life-threatening colonic hemorrhage is a very rare condition in Crohn's disease. Lower gastroinstestinal hemorrhage in Crohn's disease occurs in 0.6-2.5% of cases. In a patient presenting with severe gastrointestinal bleeding after ileocolectomy, mesenteric angiography provided precise localisation of the bleeding site in the area of the splenic flexure. (orig.)

  5. Siblings of the Child with a Life-Threatening Illness.

    Science.gov (United States)

    Sourkes, Barbara M.

    1987-01-01

    The experience of siblings of a child with a life-threatening illness may be seen at the juncture of the following perspectives: (1) the family system; (2) a focus on living rather than on dying; and (3) a view toward positive adaptation rather than toward psychopathology. The most critical focus is on the sibling-patient relationship itself. (BJV)

  6. Tension pneumothorax, is it a really life-threatening condition?

    OpenAIRE

    Yoon, Jeong Seob; Choi, Si Young; Suh, Jong Hui; Jeong, Jin Yong; Lee, Bae Young; Park, Yong Gue; Kim, Chi Kyung; Park, Chan Beom

    2013-01-01

    Background Tension pneumothorax is a life-threatening occurrence that is infrequently the consequence of spontaneous pneumothorax. The aim of this study was to identify the risk factors for the development of tension pneumothorax and its effect on clinical outcomes. Methods We reviewed patients who were admitted with spontaneous pneumothorax between August 1, 2003 and December 31, 2011. Electronic medical records and the radiological findings were reviewed with chest x-ray and high-resolution...

  7. Ectopic pregnancy: a life-threatening gynecological emergency

    OpenAIRE

    Lawani OL; Anozie OB; Ezeonu PO

    2013-01-01

    Osaheni L Lawani, Okechukwu B Anozie, Paul O Ezeonu Department of Obstetrics and Gynecology, Federal Teaching Hospital, Abakaliki, Nigeria Background: Ectopic pregnancy is a life-threatening gynecological emergency, and a significant cause of maternal morbidity and mortality in Nigeria. Objective: The aim of this work was to determine and evaluate the incidence, clinical presentation, risk factors, and management outcomes of ectopic pregnancies at Ebonyi State University Teaching Hospital (E...

  8. Life-threatening ventricular arrhythmia recognition by nonlinear descriptor

    OpenAIRE

    Krishnan Shankar; Chan Kap; Sun Yan

    2005-01-01

    Abstract Background Ventricular tachycardia (VT) and ventricular fibrillation (VF) are ventricular cardiac arrhythmia that could be catastrophic and life threatening. Correct and timely detection of VT or VF can save lives. Methods In this paper, a multiscale-based non-linear descriptor, the Hurst index, is proposed to characterize the ECG episode, so that VT and VF can be recognized as different from normal sinus rhythm (NSR) in the descriptor domain. Results This newly proposed technique wa...

  9. Life-Threatening Hypokalemic Paralysis in a Young Bodybuilder

    OpenAIRE

    Cheung, Kitty K. T.; Wing-Yee So; Kong, Alice P S; Ma, Ronald C.W.; Chow, Francis C. C.

    2014-01-01

    We report a case of life-threatening hypokalemia in a 28-year-old bodybuilder who presented with sudden onset bilateral lower limbs paralysis few days after his bodybuilding competition. His electrocardiogram (ECG) showed typical u-waves due to severe hypokalemia (serum potassium 1.6 mmol/L, reference range (RR) 3.5–5.0 mmol/L). He was admitted to the intensive care unit (ICU) and was treated with potassium replacement. The patient later admitted that he had exposed himself to weight loss age...

  10. Discussion on Teacher’s Role under Life Threatening Circumstances

    Institute of Scientific and Technical Information of China (English)

    彭璐

    2014-01-01

    This paper first reviewed a controversial case in which a teacher ran away from his students in a earthquake. Several ed-ucational ethnic questions were aroused from the case: Is protecting students part of teacher ’s job? To what extent should it be applied? etc. Then the author aims to answer these questions based on a real case study from philosophical perspective, that is, ana-lyzing teacher’s role (i) as a human being; (ii) as a educator; (iii) as a educatee. Finally the paper concludes that teachers should protect their students even under life threatening circumstances.

  11. ACUTE LIFE-THREATENING ASTHMA IN ASIR CENTRAL HOSPITAL

    OpenAIRE

    Al-Ghamdi, Badr R.; Taklu, Bayu G.

    1997-01-01

    Aim: This study was conducted to analyze the severe acute asthma admissions in Asir Central Hospital (ACH) in Abha, Saudi Arabia. In particular, it aimed to identify risk factors and final outcome of acute life-threatening asthma. Method: All patients admitted to the Intensive Care Unit (ICU) with acute bronchial asthma from June 1989 to May 1995 were analyzed. Total admis-sions to the ICU were obtained to determine the prevalence of asthma admission to the ICU. Results: There were 13 admissi...

  12. Life-threatening asthma attack during prolonged fingolimod treatment: case report

    Directory of Open Access Journals (Sweden)

    Zecca C

    2014-07-01

    Full Text Available Chiara Zecca,1,* Matteo Caporro,1,* Sandor Györik,2 Claudio Gobbi11Neurocenter of Southern Switzerland, Department of Neurology, Ospedale Regionale di Lugano, Lugano, Switzerland; 2Department of Internal Medicine, Ospedale Regionale di Bellinzona, Bellinzona, Switzerland*These authors contributed equally to this workBackground: Fingolimod (FTY mediates bronchoconstriction by interacting with sphingosine-1-phosphate receptors. The majority of the reported adverse respiratory events occur during the first weeks of treatment.Case presentation: A 49-year-old woman developed a life-threatening asthma attack after 6 months of continuous FTY treatment. The adverse event required prolonged hospitalization, and the patient recovered without sequelae after FTY interruption. A history of previous airway hyperreactivity and a concurrent viral respiratory infection possibly acted as predisposing factors.Conclusion: This first description of a severe, life-threatening asthma attack during prolonged FTY treatment suggests the need for long-term clinical surveillance, especially in patients with known predisposing factors.Keywords: multiple sclerosis, bronchial hyper-reactivity

  13. Tracheal intubation in the ICU: Life saving or life threatening?

    Directory of Open Access Journals (Sweden)

    Jigeeshu V Divatia

    2011-01-01

    Full Text Available Tracheal intubation (TI is a routine procedure in the intensive care unit (ICU, and is often life saving. However, life-threatening complications occur in a significant proportion of procedures, making TI perhaps one the most common but underappreciated airway emergencies in the ICU. In contrast to the controlled conditions in the operating room (OR, the unstable physiologic state of critically ill patients along with underevaluation of the airways and suboptimal response to pre-oxygenation are the major factors for the high incidence of life-threatening complications like severe hypoxaemia and cardiovascular collapse in the ICU. Studies have shown that strategies planned for TI in the OR can be adapted and extrapolated for use in the ICU. Non-invasive positive-pressure ventilation for pre-oxygenation provides adequate oxygen stores during TI for patients with precarious respiratory pathology. The intubation procedure should include not only airway management but also haemodynamic, gas exchange and neurologic care, which are often crucial in critically ill patients. Hence, there is a necessity for the implementation of an Intubation Bundle during routine airway management in the ICU. Adherence to a plan for difficult airway management incorporating the use of intubation aids and airway rescue devices and strategies is useful.

  14. Warfarin-induced sublingual hematoma mimicking Ludwig angina: Conservative management of a potentially life-threatening condition.

    LENUS (Irish Health Repository)

    Cashman, Emma

    2012-02-01

    Sublingual hematoma secondary to excessive anticoagulation is a rare, life-threatening condition. Reports in the literature have emphasized the importance of a prompt reversal of the causative coagulopathy by intravenous administration of vitamin K and fresh frozen plasma. In the event of an unstable airway, surgical intervention via tracheostomy or cricothyroidectomy is advocated. We report a case of sublingual hematoma that was treated conservatively, and we discuss the presentation and management of this entity.

  15. Warfarin-induced sublingual hematoma mimicking Ludwig angina: Conservative management of a potentially life-threatening condition.

    LENUS (Irish Health Repository)

    Cashman, Emma

    2011-02-01

    Sublingual hematoma secondary to excessive anticoagulation is a rare, life-threatening condition. Reports in the literature have emphasized the importance of a prompt reversal of the causative coagulopathy by intravenous administration of vitamin K and fresh frozen plasma. In the event of an unstable airway, surgical intervention via tracheostomy or cricothyroidectomy is advocated. We report a case of sublingual hematoma that was treated conservatively, and we discuss the presentation and management of this entity.

  16. [Life-threatening adverse effects of pharmacologic antihyperuricemic therapy].

    Science.gov (United States)

    Russmann, St; Lauterburg, B

    2004-09-01

    Minor hypersensitivity reactions to allopurinol presenting as skin rash occur in approximately 2% of patients. A more severe, albeit rare, hypersensitivity reaction with fever, eosinophilia, dermatitis, renal failure, vasculitis and hepatic dysfunction carries a mortality of up to 20%. The incidence of this severe reaction can probably be reduced by adjusting the dose of allopurinol in patients with impaired renal function. Azathioprine and mercaptopurine are metabolised by xanthine oxidase, the enzyme that is inhibited by allopurinol. Concomitant administration can result in life-threatening neutropenia unless the dose of allopurinol is reduced by approximately 75%. The uricosuric agent benzbromarone has recently been withdrawn from the market because of several cases of fulminant hepatic failure with subsequent death of the patient or liver transplantation. PMID:15493119

  17. Life-Threatening Lactation or "Bovine" Ketoacidosis: A Case Report.

    Science.gov (United States)

    Greaney, David J; Benson, Pat

    2016-08-15

    Lactation or "bovine" ketoacidosis is a rare cause of raised anion gap metabolic acidosis whereby a perfect storm of negative calorie balance (starvation/glucose preferentially used for milk production) and insulin resistance (counter regulatory stress hormone release/infection) leads to a dysregulated ketogenic state. We present a case of life-threatening lactation-related ketoacidosis in a patient 9 weeks postpartum, who presented to the emergency department with an arterial pH of 6.88, HCO3 of 5.8 mmol/L and blood ketone level of 5.8 mmol/L. Treatment consists of aggressive glucose loading, triggering supraphysiologic endogenous insulin release, and subsequent inhibition of ketone body formation. PMID:27310899

  18. Life-threatening complications of deep neck space infections.

    Science.gov (United States)

    Dalla Torre, Daniel; Brunold, Silvia; Kisielewsky, Irene; Kloss, Frank R; Burtscher, Doris

    2013-11-01

    Odontogenic infections represented a challenge for every craniomaxillofacial surgeon in the pre-antibiotic era, not least due to the frequent association with septic complications and lethal consequences. Nowadays, the incidences of serious infection-related complications are less frequent thanks to the medical progress. Nevertheless, the development of severe infections is still hard to foresee. The following analysis provides an overview of four patients with severe, life-threatening odontogenic deep neck space infections treated at the University Clinic for Oral and Maxillofacial Surgery in Innsbruck and describes the etiology, therapy, and outcome for each patient while analyzing differences between the single cases. Crucial aspects in origin, progression, and treatment of DNIs are highlighted, comparing the results with the international literature.

  19. The generalized second law of gravitational thermodynamics on the apparent and event horizons in FRW cosmology

    Energy Technology Data Exchange (ETDEWEB)

    Karami, K; Ghaffari, S; Soltanzadeh, M M, E-mail: KKarami@uok.ac.i [Department of Physics, University of Kurdistan, Pasdaran St, Sanandaj (Iran, Islamic Republic of)

    2010-10-21

    We investigate the validity of the generalized second law (GSL) of gravitational thermodynamics on the apparent and event horizons in a non-flat Friedmann-Robertson-Walker (FRW) universe containing dark energy interacting with dark matter. We show that for the dynamical apparent horizon, the GSL is always satisfied throughout the history of the universe for any spatial curvature and it is independent of the equation of state parameter of the interacting dark energy model. On the other hand, for the cosmological event horizon, the validity of the GSL depends on the equation of state parameter of the model.

  20. Event and Apparent Horizon Finders for 3+1 Numerical Relativity

    Directory of Open Access Journals (Sweden)

    Thornburg Jonathan

    2007-06-01

    Full Text Available Event and apparent horizons are key diagnostics for the presence and properties of black holes. In this article I review numerical algorithms and codes for finding event and apparent horizons in numerically-computed spacetimes, focusing on calculations done using the 3+1 ADM formalism. The event horizon of an asymptotically-flat spacetime is the boundary between those events from which a future-pointing null geodesic can reach future null infinity and those events from which no such geodesic exists. The event horizon is a (continuous null surface in spacetime. The event horizon is defined nonlocally in time: it is a global property of the entire spacetime and must be found in a separate post-processing phase after all (or at least the nonstationary part of spacetime has been numerically computed.There are three basic algorithms for finding event horizons, based on integrating null geodesics forwards in time, integrating null geodesics backwards in time, and integrating null surfaces backwards in time. The last of these is generally the most efficient and accurate.In contrast to an event horizon, an apparent horizon is defined locally in time in a spacelike slice and depends only on data in that slice, so it can be (and usually is found during the numerical computation of a spacetime. A marginally outer trapped surface (MOTS in a slice is a smooth closed 2-surface whose future-pointing outgoing null geodesics have zero expansion Theta. An apparent horizon is then defined as a MOTS not contained in any other MOTS. The MOTS condition is a nonlinear elliptic partial differential equation (PDE for the surface shape, containing the ADM 3-metric, its spatial derivatives, and the extrinsic curvature as coefficients. Most “apparent horizon” finders actually find MOTSs.There are a large number of apparent horizon finding algorithms, with differing trade-offs between speed, robustness, accuracy, and ease of programming. In axisymmetry, shooting

  1. Ectopic pregnancy: a life-threatening gynecological emergency

    Directory of Open Access Journals (Sweden)

    Lawani OL

    2013-08-01

    Full Text Available Osaheni L Lawani, Okechukwu B Anozie, Paul O Ezeonu Department of Obstetrics and Gynecology, Federal Teaching Hospital, Abakaliki, Nigeria Background: Ectopic pregnancy is a life-threatening gynecological emergency, and a significant cause of maternal morbidity and mortality in Nigeria. Objective: The aim of this work was to determine and evaluate the incidence, clinical presentation, risk factors, and management outcomes of ectopic pregnancies at Ebonyi State University Teaching Hospital (EBSUTH in Abakaliki. Methods: This was a retrospective, descriptive study of ectopic pregnancies managed in EBSUTH during the study period (June 1, 2002 to May 31, 2012. The medical records of the patients managed for ectopic pregnancy as well as the total birth record and gynecological admission records during the period under review were retrieved, and data were collected with the aid of data-entry forms designed for this purpose. There were 4,610 gynecological admissions and 9,828 deliveries, with 215 cases of ectopic pregnancies. A total of 205 cases were suitable for analysis after excluding cases with incomplete records. The relevant data collected were analyzed with SPSS version 15.0 for Windows. Results: Ectopic pregnancy constituted 4.5% of all gynecological admissions, and its incidence was 2.1%. The mean age of the patients was 27 ± 2 years, 196 of 205 (95.6% had ruptured ectopic pregnancies, and the remaining nine (4.4% were unruptured. The commonest (166 of 205, 80.0% clinical presentation was abdominal pain, and the commonest (105 of 205, 51.2% identified risk factor was a previous history of induced abortion. Three deaths were recorded, giving a case-fatality rate of 1.4% (three of 205. Conclusion: Ectopic pregnancy is a recognized cause of maternal morbidity and mortality and has remained a reproductive health challenge to Nigerian women, as well as a threat to efforts in achieving the UN's Millennium Development Goal 5 in sub-Saharan Africa

  2. Life-Threatening Hypokalemic Paralysis in a Young Bodybuilder

    Directory of Open Access Journals (Sweden)

    Kitty K. T. Cheung

    2014-01-01

    Full Text Available We report a case of life-threatening hypokalemia in a 28-year-old bodybuilder who presented with sudden onset bilateral lower limbs paralysis few days after his bodybuilding competition. His electrocardiogram (ECG showed typical u-waves due to severe hypokalemia (serum potassium 1.6 mmol/L, reference range (RR 3.5–5.0 mmol/L. He was admitted to the intensive care unit (ICU and was treated with potassium replacement. The patient later admitted that he had exposed himself to weight loss agents of unknown nature, purchased online, and large carbohydrate loads in preparation for the competition. He made a full recovery after a few days and discharged himself from the hospital against medical advice. The severe hypokalemia was thought to be caused by several mechanisms to be discussed in this report. With the ever rising number of new fitness centers recently, the ease of online purchasing of almost any drug, and the increasing numbers of youngsters getting into the bodybuilding arena, clinicians should be able to recognize the possible causes of sudden severe hypokalemia in these patients in order to revert the pathophysiology.

  3. Life-threatening hypokalemic paralysis in a young bodybuilder.

    Science.gov (United States)

    Cheung, Kitty K T; So, Wing-Yee; Kong, Alice P S; Ma, Ronald C W; Chow, Francis C C

    2014-01-01

    We report a case of life-threatening hypokalemia in a 28-year-old bodybuilder who presented with sudden onset bilateral lower limbs paralysis few days after his bodybuilding competition. His electrocardiogram (ECG) showed typical u-waves due to severe hypokalemia (serum potassium 1.6 mmol/L, reference range (RR) 3.5-5.0 mmol/L). He was admitted to the intensive care unit (ICU) and was treated with potassium replacement. The patient later admitted that he had exposed himself to weight loss agents of unknown nature, purchased online, and large carbohydrate loads in preparation for the competition. He made a full recovery after a few days and discharged himself from the hospital against medical advice. The severe hypokalemia was thought to be caused by several mechanisms to be discussed in this report. With the ever rising number of new fitness centers recently, the ease of online purchasing of almost any drug, and the increasing numbers of youngsters getting into the bodybuilding arena, clinicians should be able to recognize the possible causes of sudden severe hypokalemia in these patients in order to revert the pathophysiology.

  4. Life-threatening hypokalemic paralysis in a young bodybuilder.

    Science.gov (United States)

    Cheung, Kitty K T; So, Wing-Yee; Kong, Alice P S; Ma, Ronald C W; Chow, Francis C C

    2014-01-01

    We report a case of life-threatening hypokalemia in a 28-year-old bodybuilder who presented with sudden onset bilateral lower limbs paralysis few days after his bodybuilding competition. His electrocardiogram (ECG) showed typical u-waves due to severe hypokalemia (serum potassium 1.6 mmol/L, reference range (RR) 3.5-5.0 mmol/L). He was admitted to the intensive care unit (ICU) and was treated with potassium replacement. The patient later admitted that he had exposed himself to weight loss agents of unknown nature, purchased online, and large carbohydrate loads in preparation for the competition. He made a full recovery after a few days and discharged himself from the hospital against medical advice. The severe hypokalemia was thought to be caused by several mechanisms to be discussed in this report. With the ever rising number of new fitness centers recently, the ease of online purchasing of almost any drug, and the increasing numbers of youngsters getting into the bodybuilding arena, clinicians should be able to recognize the possible causes of sudden severe hypokalemia in these patients in order to revert the pathophysiology. PMID:24660073

  5. Life-threatening ventricular arrhythmia recognition by nonlinear descriptor

    Directory of Open Access Journals (Sweden)

    Krishnan Shankar

    2005-01-01

    Full Text Available Abstract Background Ventricular tachycardia (VT and ventricular fibrillation (VF are ventricular cardiac arrhythmia that could be catastrophic and life threatening. Correct and timely detection of VT or VF can save lives. Methods In this paper, a multiscale-based non-linear descriptor, the Hurst index, is proposed to characterize the ECG episode, so that VT and VF can be recognized as different from normal sinus rhythm (NSR in the descriptor domain. Results This newly proposed technique was tested using MIT-BIH malignant ventricular arrhythmia database. The relationship between the ECG episode length and the corresponding recognition performance was studied. The experiments demonstrated good performance of the proposed descriptor. An accuracy rate as high as 100% was obtained for VT/VF to be recognized from NSR; for VT and VF to be recognized from each other, the recognition accuracy varies from 84.24% to 100%. In addition, the results were compared favorably against those obtained using Complexity measure. Conclusions There is strong potential for using the Hurst index for malignant ventricular arrhythmia recognition in clinical applications.

  6. Life-threatening upper gastrointestinal bleeding due to gastric Dieulafoy's lesion: Successful minimally-invasive management.

    Science.gov (United States)

    Bondade, Nikhil; Bhandari, Suryaprakash; Rao, Prashant; Shah, Rahul; Bothara, Vishal; Maydeo, Amit

    2016-01-01

    Dieulafoy's lesion (DL) is a relatively rare, but potentially life-threatening condition. It accounts for 1-2% of acute gastrointestinal bleedings. Its serious nature makes it necessary for early diagnosis and treatment. This is a case report of a patient who presented with life-threatening haematemesis due to gastric Dieulafoy's that was successfully treated laparoscopically after failed endotherapy. PMID:27251825

  7. Suppurative meningitis: A life-threatening complication in male macroprolactinomas

    Directory of Open Access Journals (Sweden)

    Farida Chentli

    2013-01-01

    Full Text Available Background: Suppurative meningitis (SM or bacterial meningitis is a life-threatening condition, which is exceptionally due to pituitary tumors (PT. Our aim was to analyze its frequency among male macroprolactinomas (MPRL deemed to be aggressive, to report the cases we observed in our practice and describe the circumstances under which SM appeared. Materials and Methods: We retrospectively analyzed 82 male MPRL in order to look for a history of well proved SM and the circumstances under which SM appeared. We also took into account the possibility of SM relapsing. Results: Four out of 82 male MPRL had SM = 4.87%. Three consulted for SM symptoms. SM was confirmed in Infectious Diseases department, but only one had rhinorrhea. Hormonal assessment and cerebral magnetic resonance imaging pleaded for aggressive prolactinomas. After antibiotics, SM was sterilized. Then, MPRL were treated with bromocriptine, which normalized prolactin and reduced PT. SM never relapsed. The 4 th case was hospitalized for a large multidirectional prolactinoma invading and/or arising from the skull base. He was operated on 3 times and then he was given Bromocriptine. After 3 months, he had rhinorrhea and then SM which was successfully treated by antibiotics. SM never relapsed after tumor reduction. Conclusion: SM was demonstrated in 4.87%. SM has revealed MPRL in 3 cases and appeared after bromocriptine intake in the 4 th one. Endocrinologists should be aware of this severe condition, which can be avoided by repairing as soon as possible the bony defect secondary to aggressive tumors, unless it is clogged by fibrosis: What probably happened in our cases.

  8. Life-threatening Cerebral Edema Caused by Acute Occlusion of a Superior Vena Cava Stent

    Energy Technology Data Exchange (ETDEWEB)

    Sofue, Keitaro, E-mail: keitarosofue@yahoo.co.jp; Takeuchi, Yoshito, E-mail: yotake62@qg8.so-net.ne.jp; Arai, Yasuaki, E-mail: arai-y3111@mvh.biglobe.ne.jp [National Cancer Center Hospital, Department of Diagnostic Radiology (Japan); Sugimura, Kazuro, E-mail: sugimura@med.kobe-u.ac.jp [Kobe University, Department of Radiology, Graduate School of Medicine (Japan)

    2013-02-15

    A71-year-old man with advanced lung cancer developed a life-threatening cerebral edema caused by the acute occlusion of a superior vena cava (SVC) stent and was successfully treated by an additional stent placement. Although stent occlusion is a common early complication, no life-threatening situations have been reported until now. Our experience highlights the fact that acute stent occlusion can potentially lead to the complete venous shutdown of the SVC, resulting in life-threatening cerebral edema, after SVC stent placement. Immediate diagnosis and countermeasures are required.

  9. A life-threatening flecainide overdose treated with intravenous fat emulsion.

    Science.gov (United States)

    Ellsworth, Heather; Stellpflug, Samuel J; Cole, Jon B; Dolan, Joseph A; Harris, Carson R

    2013-03-01

    Flecainide is a Vaughan Williams Class Ic antidysrhythmic associated with PR, QRS, and QTc prolongation on the electrocardiogram and development of life-threatening cardiac toxicity in overdose. The cornerstone of treatment is fluid resuscitation and the administration of magnesium and sodium bicarbonate. We report a case of flecainide overdose associated with life-threatening hemodynamic compromise successfully treated with intravenous fat emulsion (IFE) therapy. IFE should be considered as a novel adjunctive therapy in patients with life-threatening toxicity following flecainide overdose.

  10. A Life-Threatening Multilocalized Hidradenitis Suppurativa Case

    Science.gov (United States)

    Buyukasik, Oktay; Osmanoglu, C. Gokhan; Polat, Yilmaz; Kargici, Hulagu; Kaya, Gulay

    2005-01-01

    Abstract and Introduction Abstract The patient was a 38-year-old man. He had been suffering from hidradenitis suppurativa (HS) for approximately 20 years. He had active lesions at both axillas, hip, scrotum, and perineum, and inactive lesions located behind the ears, lower abdomen, and posterior neck. He was monitored and treated at different branches; he continuously used antibiotics and was given steroids at times. Antibiotic resistance developed subsequently. His general situation was bad; vital signs were poor; and he was in a state of sepsis and preshock, so this case was regarded as life-threatening. Total excision was performed first on the lesion at the right axilla, then on the lesion at the left axilla, and the parascapular fasciocutaneous flap was reversed. A skin graft was applied to the triangular defect on the scapula. No relapse occurred. Then the lesions at the hip were managed. Broad excision was used twice with the patient under general anesthesia; because the lesions spread to the retrococcygeal and gluteal muscles, coccyx resection and partial gluteal muscle resection were implemented. The defect was eliminated with a progressive flap. At the intergluteal sulcus, small lesions emerging at the median line were debrided with the patient under local anesthesia, and together with secondary recovery, the disease was completely managed. Lesions at the perineum and scrotum and at both inguinal areas were broadly excised and grafted. No lesion has relapsed so far. One year later, Hodgkin's lymphoma was diagnosed, and the patient was treated with chemoradiotherapy easily, because there was no infective focus. The disease is in remission now. The patient weighs 110 kg, is healthy, and is working again. Introduction HS is a disease that is characterized by intensive development of sclerosis due to abscess, sinus and fistula formation, and fibrosis as a result of a chronic infection of the apocrine sweat glands. The disease can be seen at the scrotum

  11. Successfull Management of a Life Threatening Cerebellar Haemorrhage Following Spine Surgery - A Case Report -

    OpenAIRE

    Pallud, Johan; Belaïd, Hayat; Aldea, Sorin

    2009-01-01

    Cerebellar haemorrhages are rare life-threatening complications following spine surgery that present challenges for their diagnostic and their therapeutic management. Their patho-physiology remains unclear. We report a case of a life-threatening cerebellar haemorrhage secondary to an occult dural tear following a planned L5-S1 laminectomy. The patient was treated with emergent external ventriculostomy following by a posterior fossa decompressive craniectomy. Cerebellar haemorrhages have to be...

  12. Brazilian network for the surveillance of maternal potentially life threatening morbidity and maternal near-miss and a multidimensional evaluation of their long term consequences

    OpenAIRE

    Surita Fernanda G; Pinto e Silva João L; Passini Renato; Costa Maria L; Zanardi Dulce T; Silveira Carla; Pacagnella Rodolfo C; Camargo Rodrigo S; Haddad Samira M; Parpinelli Mary A; Souza João P; Cecatti Jose G; Sousa Maria H; Calderon Iracema MP; Say Lale

    2009-01-01

    Abstract Background It has been suggested that the study of women who survive life-threatening complications related to pregnancy (maternal near-miss cases) may represent a practical alternative to surveillance of maternal morbidity/mortality since the number of cases is higher and the woman herself is able to provide information on the difficulties she faced and the long-term repercussions of the event. These repercussions, which may include sexual dysfunction, postpartum depression and post...

  13. Enteral voriconazole induced hypoglycemia: A potentially life threatening complication

    Directory of Open Access Journals (Sweden)

    Tanmoy Ghatak

    2012-01-01

    Full Text Available Voriconazole is a newer effective antifungal agent currently available for the treatment of invasive aspergillosis. The case we present describes an episode of serious persistent hypoglycemia after voriconazole therapy and we believe that this strongly contributed to this event. It is a warning to all that voriconazole has a propensity to alter glucose homeostasis in the presence of kidney disturbance.

  14. Odontogenic deep neck space infection as life-threatening condition in pregnancy.

    Science.gov (United States)

    Dalla Torre, D; Burtscher, D; Höfer, D; Kloss, F R

    2014-09-01

    Odontogenic deep neck space infections represent a severe disease with possible life-threatening complications. Despite knowledge of these infectious diseases, treatment remains a challenge for every maxillofacial surgeon. Therapy of severe neck infections is even more crucial during pregnancy because of the possible life-threatening situation for both the mother and the foetus. The possible compromise of oral health during pregnancy is well known, however severe odontogenic infections are rarely considered in the literature. The following case report describes the dramatic course of a deep neck space infection in a pregnant patient, commencing with typical symptoms of localized odontogenic infection and ending in a critical, life-threatening condition for the patient and a lethal condition for the foetus. The case represents the first description of intrauterine, foetal death caused by a deep neck space infection. Implications for dental and medical treatment during pregnancy, especially regarding odontogenic infections, are presented and discussed with findings in the international literature.

  15. Self-reported recognition of undiagnosed life threatening conditions in chiropractic practice: a random survey

    Directory of Open Access Journals (Sweden)

    Daniel Dwain M

    2012-07-01

    Full Text Available Abstract Background The purpose of this study was to identify the type and frequency of previously undiagnosed life threatening conditions (LTC, based on self-reports of chiropractic physicians, which were first recognized by the chiropractic physician. Additionally this information may have a preliminary role in determining whether chiropractic education provides the knowledge necessary to recognize these events. Methods The study design was a postal, cross-sectional, epidemiological self-administered survey. Two thousand Doctors of Chiropractic in the US were randomly selected from a list of 57878. The survey asked respondents to state the number of cases from the list where they were the first physician to recognize the condition over the course of their practice careers. Space was provided for unlisted conditions. Results The response rate was 29.9%. Respondents represented 11442 years in practice and included 3861 patients with a reported undiagnosed LTC. The most commonly presenting conditions were in rank order: carcinoma, abdominal aneurysm, deep vein thrombosis, stroke, myocardial infarction, subdural hematoma and a large group of other diagnoses. The occurrence of a previously undiagnosed LTC can be expected to present to the chiropractic physician every 2.5 years based on the responding doctors reports. Conclusion Based on this survey chiropractic physicians report encountering undiagnosed LTC’s in the normal course of practice. The findings of this study are of importance to the chiropractic profession and chiropractic education. Increased awareness and emphasis on recognition of LTC is a critical part of the education process and practice life.

  16. Life Threatening Idiopathic Recurrent Angioedema Responding to Cannabis

    Directory of Open Access Journals (Sweden)

    Amit Frenkel

    2015-01-01

    Full Text Available We present a case of a 27-year-old man with recurrent episodes of angioedema since he was 19, who responded well to treatment with medical grade cannabis. Initially, he responded to steroids and antihistamines, but several attempts to withdraw treatment resulted in recurrence. In the last few months before prescribing cannabis, the frequency and severity of the attacks worsened and included several presyncope events, associated with scrotal and neck swelling. No predisposing factors were identified, and extensive workup was negative. The patient reported that he was periodically using cannabis socially and that during these periods he was free of attacks. Recent data suggest that cannabis derivatives are involved in the control of mast cell activation. Consequently, we decided to try a course of inhaled cannabis as modulators of immune cell functions. The use of inhaled cannabis resulted in a complete response, and he has been free of symptoms for 2 years. An attempt to withhold the inhaled cannabis led to a recurrent attack within a week, and resuming cannabis maintained the remission, suggesting a cause and effect relationship.

  17. Knee Pain in Children, Part II: Limb- and Life-threatening Conditions, Hip Pathology, and Effusion.

    Science.gov (United States)

    Wolf, Michael

    2016-02-01

    On the basis of primarily consensus due to lack of relevant clinical studies, the most important evaluative step for knee pain is to identify any emergent conditions, including limb- and life-threatening disorders (septic arthritis, osteomyelitis, and malignancy), hip pathology, or conditions associated with effusions. (2)(3)(6)(8)(11)(13)(14) PMID:26834226

  18. An extended family suddenly confronted with a life-threatening hereditary arrhythmia

    NARCIS (Netherlands)

    Hendriks, K.S.W.H.; Van Langen, I.M.; Van Tintelen, J.P.; Grosfeld, F.J.M.; Wilde, A.A.M.; Ten Kroode, H.F.J.

    2005-01-01

    Objective. This exploratory study serves to illustrate the psychological impact on an extended family in the process of genetic counselling and testing for a potentially life-threatening arrhythmia, the long-QT syndrome (LQTS). Method. All members of the third generation and their partners (n=11) we

  19. Life-threatening Pneumocystis jiroveci pneumonia following treatment of severe Cushing's syndrome

    NARCIS (Netherlands)

    Oosterhuis, J. K.; van den Berg, G.; Monteban-Kooistra, W. E.; Ligtenberg, J. J. M.; Tulleken, J. E.; Zijlstra, J. G.; Meertens, John

    2007-01-01

    We describe two patients with a severe Cushing's syndrome due to ectopic production of ACTH. Both patients developed a life-threatening Pneumocystis jiroveci pneumonia (PCP) shortly after treatment of the hypercortisolism was started by means of inhibition of production of glucocorticoids and glucoc

  20. Candida albicans-associated necrotizing vasculitis producing life-threatening gastrointestinal hemorrhage.

    LENUS (Irish Health Repository)

    Sargent, Jeremy

    2012-02-01

    Patients undergoing treatment of acute lymphoblastic leukemia are at risk for fungal infections including disseminated candidiasis. We describe a case of systemic Candida albicans infection associated with life-threatening gastrointestinal hemorrhage due to unusual necrotizing vasculitis involving the gastrointestinal tract. We explore the association between Candida and such vasculopathy.

  1. Preparing School Personnel to Assist Students with Life-Threatening Food Allergies.

    Science.gov (United States)

    Hay, Genevieve H.; And Others

    1994-01-01

    Knowledge of and preparation for life-threatening food allergies will enable school personnel to better respond to students who have severe allergic reactions. Given the high incidence of food-related anaphylaxis in public places, teachers and school personnel should be aware of and prepared to handle severe food allergy reactions. (SM)

  2. Can we identify patients at risk of life-threatening allergic reactions to food?

    Science.gov (United States)

    Turner, P J; Baumert, J L; Beyer, K; Boyle, R J; Chan, C-H; Clark, A T; Crevel, R W R; DunnGalvin, A; Fernández-Rivas, M; Gowland, M H; Grabenhenrich, L; Hardy, S; Houben, G F; O'B Hourihane, J; Muraro, A; Poulsen, L K; Pyrz, K; Remington, B C; Schnadt, S; van Ree, R; Venter, C; Worm, M; Mills, E N C; Roberts, G; Ballmer-Weber, B K

    2016-09-01

    Anaphylaxis has been defined as a 'severe, life-threatening generalized or systemic hypersensitivity reaction'. However, data indicate that the vast majority of food-triggered anaphylactic reactions are not life-threatening. Nonetheless, severe life-threatening reactions do occur and are unpredictable. We discuss the concepts surrounding perceptions of severe, life-threatening allergic reactions to food by different stakeholders, with particular reference to the inclusion of clinical severity as a factor in allergy and allergen risk management. We review the evidence regarding factors that might be used to identify those at most risk of severe allergic reactions to food, and the consequences of misinformation in this regard. For example, a significant proportion of food-allergic children also have asthma, yet almost none will experience a fatal food-allergic reaction; asthma is not, in itself, a strong predictor for fatal anaphylaxis. The relationship between dose of allergen exposure and symptom severity is unclear. While dose appears to be a risk factor in at least a subgroup of patients, studies report that individuals with prior anaphylaxis do not have a lower eliciting dose than those reporting previous mild reactions. It is therefore important to consider severity and sensitivity as separate factors, as a highly sensitive individual will not necessarily experience severe symptoms during an allergic reaction. We identify the knowledge gaps that need to be addressed to improve our ability to better identify those most at risk of severe food-induced allergic reactions. PMID:27138061

  3. Guidelines for Managing Life-Threatening Food Allergies in Massachusetts Schools

    Science.gov (United States)

    Sheetz, Anne H.; Goldman, Patricia G.; Millett, Kathleen; Franks, Jane C.; McIntyre, C. Lynne; Carroll, Constance R.; Gorak, Diane; Harrison, Christanne Smith; Carrick, Michele Abu

    2004-01-01

    During the past decade, prevalence of food allergies among children increased. Caring for children with life-threatening food allergies has become a major challenge for school personnel Prior to 2002, Massachusetts did not provide clear guidelines to assist schools in providing a safe environment for these children and preparing for an emergency…

  4. Fever-Induced Life-Threatening Arrhythmias in Children Harboring an SCN5A Mutation

    NARCIS (Netherlands)

    P. Chockalingam; L.A. Rammeloo; P.G. Postema; J. Hruda; S.A.B. Clur; N.A. Blom; A.A. Wilde

    2011-01-01

    Cardiac channelopathies caused by SCN5A mutation are well tolerated by most patients. However, the dramatic presentation of a previously healthy 4-month-old girl with life-threatening arrhythmias and the subsequent findings in the child and her family provide evidence that loss-of-function sodium ch

  5. Early onset life-threatening myelosuppression after low dose of intravesical thiotepa

    OpenAIRE

    Agnelli, Giancarlo; Gresele, Paolo; de Cunto, Maria; del Favero, Albano

    1982-01-01

    Intravesical instillation of thiotepa is a popular treatment for localized bladder carcinoma. The drug can enter the systemic circulation, and such absorption may be enhanced by extensive tumour infiltration or by a recent tumour resection. A case is reported of early onset life-threatening pancytopenia following an unusually low dose of the drug in a patient who had undergone a recent tumour resection.

  6. Participation of Life-Threatened Children and Their Parents in Therapeutic Decision Making

    Science.gov (United States)

    Bishop, Agnes Joyce

    1978-01-01

    Describes a model of therapeutic decision-making for life-threatened children, i.e., the balancing of benefits versus risks of the disease and treatment for the child. Impact of therapy on the child and his parents and the time frame for the decision-making are outlined. (Author)

  7. A life-threatening case of disseminated nocardiosis due to Nocardia brasiliensis

    Directory of Open Access Journals (Sweden)

    Elisabeth Paramythiotou

    2012-01-01

    Full Text Available Nocardiosis is a rare disease caused by infection with Nocardia species, aerobic actinomycetes with a worldwide distribution. A rare life-threatening disseminated Nocardia brasiliensis infection is described in an elderly, immunocompromised patient. Microorganism was recovered from bronchial secretions and dermal lesions, and was identified using molecular assays. Prompt, timely diagnosis and appropriate treatment ensured a favorable outcome.

  8. A life-threatening respiratory complication of gastro-oesophageal reflux in a patient with tetraplegia.

    OpenAIRE

    Donald, I P; Gear, M. W.; Wilkinson, S P

    1987-01-01

    Recurrent attacks of life-threatening dyspnoea and choking occurred in a patient with tetraplegia. Conventional investigations for gastro-oesophageal reflux were normal, but 24-hour oesophageal pH recording revealed gross reflux in association with an attack of dyspnoea. Surgical correction of the reflux abolished the attacks. The possibility of autonomic dysreflexia as the mechanism linking reflux and respiratory symptoms in this patient is discussed.

  9. Drug-Related Hyponatremic Encephalopathy: Rapid Clinical Response Averts Life-Threatening Acute Cerebral Edema

    Science.gov (United States)

    Siegel, Arthur J.; Forte, Sophie S.; Bhatti, Nasir A.; Gelda, Steven E.

    2016-01-01

    Patient: Female, 63 Final Diagnosis: Drug-induced hyponatremic encephalopathy Symptoms: Seizures • coma Medication: Hypertonic 3% saline infusion Clinical Procedure: — Specialty: Internal Medicine Objective: Unusual clinical course Background: Drug-induced hyponatremia characteristically presents with subtle psychomotor symptoms due to its slow onset, which permits compensatory volume adjustment to hypo-osmolality in the central nervous system. Due mainly to the syndrome of inappropriate antidiuretic hormone secretion (SIADH), this condition readily resolves following discontinuation of the responsible pharmacological agent. Here, we present an unusual case of life-threatening encephalopathy due to adverse drug-related effects, in which a rapid clinical response facilitated emergent treatment to avert life-threatening acute cerebral edema. Case Report: A 63-year-old woman with refractory depression was admitted for inpatient psychiatric care with a normal physical examination and laboratory values, including a serum sodium [Na+] of 144 mEq/L. She had a grand mal seizure and became unresponsive on the fourth day of treatment with the dual serotonin and norepinephrine reuptake inhibitor [SNRI] duloxetine while being continued on a thiazide-containing diuretic for a hypertensive disorder. Emergent infusion of intravenous hypertonic (3%) saline was initiated after determination of a serum sodium [Na+] of 103 mEq/L with a urine osmolality of 314 mOsm/kg H20 and urine [Na+] of 12 mEq/L. Correction of hyposmolality in accordance with current guidelines resulted in progressive improvement over several days, and she returned to her baseline mental status. Conclusions: Seizures with life-threatening hyponatremic encephalopathy in this case likely resulted from co-occurring SIADH and sodium depletion due to duloxetine and hydrochlorothiazide, respectively. A rapid clinical response expedited diagnosis and emergent treatment to reverse life-threatening acute cerebral edema

  10. High frequency oscillatory ventilation as the most appropriate treatment for life threatening thoracic trauma

    OpenAIRE

    2012-01-01

    Acute respiratory failure is common in trauma patients and can be a threat to life in severe thoracic injury. We represent a case of severe respiratory failure after blunt thoracic injury with uncontrollable bleeding and massive air leak which was successfully managed with high frequency oscillatory ventilation. In our opinion high frequency oscillatory ventilation represent a safe and effective treatment of life threatening acute respiratory failure in trauma patients.

  11. Endoclipping treatment of life-threatening rectal bleeding after prostate biopsy

    OpenAIRE

    Katsinelos, Panagiotis; Kountouras, Jannis; Dimitriadis, Georgios; Chatzimavroudis, Grigoris; Zavos, Christos; Pilpilidis, Ioannis; Paroutoglou, George; Germanidis, George; Mimidis, Kostas

    2009-01-01

    Rectal bleeding is frequently seen in patients undergoing transrectal ultrasound (TRUS)-guided multiple biopsy of the prostate, but is usually mild and stops spontaneously. We report what is believed to be the first case of life-threatening rectal bleeding following this procedure, which was successfully treated by endoscopic intervention through placement of three clips on the sites of bleeding. This case emphasizes endoscopic intervention associated with endoclipping as a safe and effective...

  12. Early onset life-threatening myelosuppression after low dose of intravesical thiotepa

    Science.gov (United States)

    Agnelli, Giancarlo; Gresele, Paolo; de Cunto, Maria; del Favero, Albano

    1982-01-01

    Intravesical instillation of thiotepa is a popular treatment for localized bladder carcinoma. The drug can enter the systemic circulation, and such absorption may be enhanced by extensive tumour infiltration or by a recent tumour resection. A case is reported of early onset life-threatening pancytopenia following an unusually low dose of the drug in a patient who had undergone a recent tumour resection. PMID:6812036

  13. Life-threatening acute pneumonitis in mixed connective tissue disease: a case report and literature review.

    Science.gov (United States)

    Rath, Eva; Zandieh, Shahin; Löckinger, Alexander; Hirschl, Mirko; Klaushofer, Klaus; Zwerina, Jochen

    2015-10-01

    Mixed connective tissue disease (MCTD) is a rare connective tissue disease frequently involving the lungs. The main characteristic is a systemic sclerosis-like picture of slowly progressing interstitial lung disease consistent with lung fibrosis, while pulmonary arterial hypertension is rare. Herein, we present a case of a newly diagnosed MCTD patient developing life-threatening acute pneumonitis similar to lupus pneumonitis. Previous literature on this exceptionally rare complication of MCTD is reviewed and differential diagnosis and management discussed. PMID:26142172

  14. Maternal morbidity in Uganda : Studies on life-threatening pregnancy complcations in low-income settings

    OpenAIRE

    Okong, Pius

    2004-01-01

    Introduction: Life-threatening complications in pregnancy rarely achieves public health prominence in the same way as maternal mortality partly because they represent a wide spectrum of conditions. The improved level of care in many high-income countries has significantly reduced morbidity and risk of death from these conditions. However in low-income countries, such as Uganda, weak and poorly resourced health systems, socio -cultural factors and the threat by HIV/AIDS combi...

  15. A UK-Wide Survey of Life-Threatening Thyroidectomy Complications

    Directory of Open Access Journals (Sweden)

    Z. K. Hassan-Smith

    2011-01-01

    Full Text Available Background and Aims. Complications following thyroidectomy can prolong hospital stay and cause significant morbidity particularly for patients treated for benign thyroid conditions. Our aim was to administer a UK-wide survey of thyroid surgery units on frequency and timing of the onset of life-threatening airway complications & correlate to factors that might be associated with them. Methods. A questionnaire including the number of and timing of the onset of life-threatening airway complications, number of thyroidectomy procedures performed per year, surgeon years of experience, the use of difficult airway management protocol, post-operative patient destination, and patient deaths, was sent to 80 UK surgical units. Results. 23/41 hospitals responded reported no postthyroidectomy airway complications. Life-threatening airways complications all occurred within the first 12 hours postoperatively, with 9 cases occurring in the recovery room and in less than 2 hours, 3 cases occurring 2–6 hours, and 3 cases occurring 6 to 12 hours after surgery. Conclusion. The results may support recent publications that advocate thyroidectomy as a less-than-24-hour surgery procedure in selected patients. Further a larger study and standardised protocol are required to establish patients' selection criteria to determine who are likely to develop serious postoperative complication and may require HDU bed.

  16. A UK-Wide Survey of Life-Threatening Thyroidectomy Complications.

    Science.gov (United States)

    Hassan-Smith, Z K; Gopinath, P; Mihaimeed, F

    2011-01-01

    Background and Aims. Complications following thyroidectomy can prolong hospital stay and cause significant morbidity particularly for patients treated for benign thyroid conditions. Our aim was to administer a UK-wide survey of thyroid surgery units on frequency and timing of the onset of life-threatening airway complications & correlate to factors that might be associated with them. Methods. A questionnaire including the number of and timing of the onset of life-threatening airway complications, number of thyroidectomy procedures performed per year, surgeon years of experience, the use of difficult airway management protocol, post-operative patient destination, and patient deaths, was sent to 80 UK surgical units. Results. 23/41 hospitals responded reported no postthyroidectomy airway complications. Life-threatening airways complications all occurred within the first 12 hours postoperatively, with 9 cases occurring in the recovery room and in less than 2 hours, 3 cases occurring 2-6 hours, and 3 cases occurring 6 to 12 hours after surgery. Conclusion. The results may support recent publications that advocate thyroidectomy as a less-than-24-hour surgery procedure in selected patients. Further a larger study and standardised protocol are required to establish patients' selection criteria to determine who are likely to develop serious postoperative complication and may require HDU bed. PMID:21331334

  17. Chalearn looking at people 2015: Apparent age and cultural event recognition datasets and results

    DEFF Research Database (Denmark)

    Escalera, Sergio; Fabian, Junior; Baro, Xavier;

    2015-01-01

    Following previous series on Looking at People (LAP) competitions [14, 13, 11, 12, 2], in 2015 ChaLearn ran two new competitions within the field of Looking at People: (1) age estimation, and (2) cultural event recognition, both in still images. We developed a crowd-sourcing application to collec...

  18. Life-threatening false alarm rejection in ICU: using the rule-based and multi-channel information fusion method.

    Science.gov (United States)

    Liu, Chengyu; Zhao, Lina; Tang, Hong; Li, Qiao; Wei, Shoushui; Li, Jianqing

    2016-08-01

    False alarm (FA) rates as high as 86% have been reported in intensive care unit monitors. High FA rates decrease quality of care by slowing staff response times while increasing patient burdens and stresses. In this study, we proposed a rule-based and multi-channel information fusion method for accurately classifying the true or false alarms for five life-threatening arrhythmias: asystole (ASY), extreme bradycardia (EBR), extreme tachycardia (ETC), ventricular tachycardia (VTA) and ventricular flutter/fibrillation (VFB). The proposed method consisted of five steps: (1) signal pre-processing, (2) feature detection and validation, (3) true/false alarm determination for each channel, (4) 'real-time' true/false alarm determination and (5) 'retrospective' true/false alarm determination (if needed). Up to four signal channels, that is, two electrocardiogram signals, one arterial blood pressure and/or one photoplethysmogram signal were included in the analysis. Two events were set for the method validation: event 1 for 'real-time' and event 2 for 'retrospective' alarm classification. The results showed that 100% true positive ratio (i.e. sensitivity) on the training set were obtained for ASY, EBR, ETC and VFB types, and 94% for VTA type, accompanied by the corresponding true negative ratio (i.e. specificity) results of 93%, 81%, 78%, 85% and 50% respectively, resulting in the score values of 96.50, 90.70, 88.89, 92.31 and 64.90, as well as with a final score of 80.57 for event 1 and 79.12 for event 2. For the test set, the proposed method obtained the score of 88.73 for ASY, 77.78 for EBR, 89.92 for ETC, 67.74 for VFB and 61.04 for VTA types, with the final score of 71.68 for event 1 and 75.91 for event 2. PMID:27454710

  19. Life-threatening ACE inhibitor-induced angio-oedema successfully treated with icatibant

    DEFF Research Database (Denmark)

    Ostenfeld, Sarah; Bygum, Anette; Rasmussen, Eva Rye

    2015-01-01

    We present a case of a 75-year-old woman treated with an ACE inhibitor, who presented with angio-oedema of the tongue and had difficulty speaking. No symptoms of anaphylaxis or urticaria were present. The patient was treated intravenously with antihistamine and glucocorticoid in combination....... Although the angio-oedema was potentially life threatening, the patient avoided intubation and mechanical ventilation. ACE inhibitor-induced angio-oedema is most likely caused by an accumulation of bradykinin and substance P. Consequently, a bradykinin receptor antagonist is the rational treatment...

  20. A pediatric case of life-threatening airway obstruction caused by a cervicomediastinal thymic cyst

    Energy Technology Data Exchange (ETDEWEB)

    Komura, Makoto; Kanamori, Yutaka; Sugiyama, Masahiko; Iwanaka, Tadashi [University of Tokyo Hospital, Department of Pediatric Surgery, Tokyo (Japan); Fukushima, Noriyoshi [University of Tokyo Hospital, Department of Pathology, Tokyo (Japan)

    2010-09-15

    Most patients with thymic cysts complain of a slowly enlarging, asymptomatic cervical mass. Only 6-10% suffer dysphagia, dyspnoea, stridor, cervical pain or vocal paralysis. In some rare cases sudden onset of severe dyspnoea or asphyxia is the first symptom, especially in neonates and small infants. We report a unique case of a 20-month-old child, who required emergency tracheal intubation due to asphyxia. Cervicomediastinal thymic cyst might need to be included in causes of life-threatening airway obstruction in young children. (orig.)

  1. Life Threatening, Allopurinol-related Dress Syndrome as a Rare Cause of Fever of Unknown Origin.

    Science.gov (United States)

    Civardi, Giuseppe; Zanlari, Luca; Bassi, Emanuele; Zangrandi, Adriano; Maria Cesinaro, Anna; Nosseir, Sofia; De Maria, Nicola

    2015-01-01

    Drug reaction eosinophilia with systemic symptoms (DRESS) syndrome is a potentially life threatening condition secondary to the usage of a wide type of drugs. A 38-year-old woman under allopurinol therapy for hyperuricemia was admitted in our department with fever and a diffuse cutaneous erythematous eruption. A few days after admission she developed rapidly progressive signs of acute liver and kidney failure. Subsequently, her clinical conditions shortly improved. The histologic findings obtained from skin and liver biopsies were consistent with a toxic drug reaction. The patient completely recovered and has been healthy for five years.

  2. Life-threatening Anemia with Hemolysis, Thrombocytopenia and Brain Atrophy due to Vitamin B12 Deficiency

    Directory of Open Access Journals (Sweden)

    Ebru Yilmaz Keskin

    2014-08-01

    Full Text Available Megaloblastic anemia due to vitamin B12 deficiency is rare in infancy. It usually occurs in exclusively breast-fed infants born to vitamin B12-deficient mothers. We report a one-year-old female infant with initial diagnosis of leukemia who was found severely vitamin B12-deficient secondary to maternal deficiency. She had marked neurodevelopmental retardation, and presented with life-threatening anemia, findings of hemolysis, thrombocytopenia and cerebral atrophy on magnetic resonance imaging. [Cukurova Med J 2014; 39(4.000: 900-904

  3. The Event Detection and the Apparent Velocity Estimation Based on Computer Vision

    Science.gov (United States)

    Shimojo, M.

    2012-08-01

    The high spatial and time resolution data obtained by the telescopes aboard Hinode revealed the new interesting dynamics in solar atmosphere. In order to detect such events and estimate the velocity of dynamics automatically, we examined the estimation methods of the optical flow based on the OpenCV that is the computer vision library. We applied the methods to the prominence eruption observed by NoRH, and the polar X-ray jet observed by XRT. As a result, it is clear that the methods work well for solar images if the images are optimized for the methods. It indicates that the optical flow estimation methods in the OpenCV library are very useful to analyze the solar phenomena.

  4. Threatened fertility and gonadal function after a polytraumatic, life-threatening injury

    Directory of Open Access Journals (Sweden)

    Ward Michael

    2010-01-01

    Full Text Available Trauma literature regarding management of genitalia trauma affecting future fertility and gonadal function in the face of coexisting life-threatening injuries is underdeveloped. We present a unique case that necessitated integrative management of a 24-year-old male who became entangled within the blades of a manure spreader and presented with life-threatening trauma in addition to severe genital trauma, including penile degloving, bilateral testicular avulsion and bilateral spermatic cord laceration. During the initial stabilization and surgical management, urology and plastic surgery were consulted to assess the urogenital injuries. Together, the surgical team orchestrated potentially life-saving interventions while successfully performing both a testicular sperm extraction and a testicular revascularization. Viable sperm was collected on the day of surgery and initial follow-up showed preserved sexual function and adequate perfusion to the testicle. This report presents a case and provides a review discussing the management of traumatic genital injuries and the importance of early involvement of surgical specialties in genitalia trauma to optimize future fertility and gonadal function. The literature search was performed in August 2008 using Medline for articles only in English, including any of the following terms: polytrauma, trauma, penis, testicle, degloving, avulsion, spermatic cord, laceration, fertility, reproduction or revascularization.

  5. Embolization of Life-Threatening Arterial Rupture in Patients with Vascular Ehlers–Danlos Syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Okada, Takuya, E-mail: okabone@gmail.com [Assistance Publique des Hôpitaux de Paris, Georges Pompidou European Hospital, Interventional Radiology Department (France); Frank, Michael, E-mail: michael.frank@egp.aphp.fr [Assistance Publique des Hôpitaux de Paris, Georges Pompidou European Hospital, Rare Vascular Diseases Reference Center (France); Pellerin, Olivier, E-mail: olivier@pellerin.as; Primio, Massimiliano Di, E-mail: massimiliano.di.primio@gmail.com; Angelopoulos, Georgios, E-mail: giorginos78@msn.com [Assistance Publique des Hôpitaux de Paris, Georges Pompidou European Hospital, Interventional Radiology Department (France); Boughenou, Marie-Fazia, E-mail: marie-fazia.boughenou@egp.aphp.fr [Assistance Publique des Hôpitaux de Paris, Georges Pompidou European Hospital, Anesthesia and Surgical Intensive Care Unit (France); Pagny, Jean-Yves, E-mail: jean-yves.pagny@egp.aphp.fr [Assistance Publique des Hôpitaux de Paris, Georges Pompidou European Hospital, Interventional Radiology Department (France); Messas, Emmanuel, E-mail: emmanuel.messas@egp.aphp.fr [Assistance Publique des Hôpitaux de Paris, Georges Pompidou European Hospital, Rare Vascular Diseases Reference Center (France); Sapoval, Marc, E-mail: marc.sapoval2@egp.aphp.fr [Assistance Publique des Hôpitaux de Paris, Georges Pompidou European Hospital, Interventional Radiology Department (France)

    2013-05-09

    PurposeTo evaluate the safety and efficacy of transarterial embolization of life-threatening arterial rupture in patients with vascular Ehlers–Danlos syndrome (vEDS) in a single tertiary referral center.MethodsWe retrospectively analyzed transarterial embolization for vEDS performed at our institution from 2000 to 2012. The indication of embolization was spontaneous arterial rupture or pseudoaneurysm with acute bleeding. All interventions used a percutaneous approach through a 5F or less introducer sheath. Embolic agents were microcoils and glue in 3 procedures, glue alone in 2, and microcoils alone in 2.ResultsFive consecutive vEDS patients were treated by 7 embolization procedures (4 women, mean age 29.8 years). All procedures were successfully performed. Two patients required a second procedure for newly arterial lesions at a different site from the first procedure. Four of the five patients were still alive after a mean follow-up of 19.4 (range 1–74.7) months. One patient died of multiple organ failure 2 days after procedure. Minor procedural complications were observed in 3 procedures (43 %), all directly managed during the same session. Remote arterial lesions occurred after 3 procedures (43 %); one underwent a second embolization, and the other 2 were observed conservatively. Puncture site complication was observed in only one procedure (14 %).ConclusionEmbolization for vEDS is a safe and effective method to manage life-threatening arterial rupture.

  6. Evento com aparente risco de morte recorrente como manifestação inicial de síndrome miastênica congênita Evento con aparente riesgo de muerte recurrente como manifestación inicial de síndrome miasténico congénito Recurrent apparent life-threatening event as the first manifestation of congenital myasthenia

    OpenAIRE

    Mariana Tresoldi das N. Romaneli; Carla Cristina T. de S. Castro; Fraga, Andrea de Melo A.; Elizete Aparecida Lomazi; Anamarli Nucci; Antonia Teresinha Tresoldi

    2013-01-01

    OBJETIVO: Alertar os pediatras sobre a necessidade de investigar criteriosamente a etiologia de eventos com aparente risco de morte recorrente. Não foram encontrados relatos associando tais eventos à miastenia congênita. DESCRIÇÃO DO CASO: Lactente de sete meses apresentando história de eventos com aparente risco de morte recorrente foi internado para investigação. Durante a internação, apresentou cianose e dispneia progressiva, com necessidade de ventilação mecânica por três dias. Após a mel...

  7. Diffuse Alveolar Hemorrhage: A Rare Life-Threatening Condition in Systemic Lupus Erythematosus

    Directory of Open Access Journals (Sweden)

    Ravi Paul Singh Virdi

    2012-01-01

    Full Text Available Diffuse alveolar hemorrhage (DAH is a rare life-threatening complication in systemic lupus erythematosus (SLE associated with high mortality rates. DAH is more common in women, and mean age of onset is around 30 years. It mostly occurs in patients with established diagnosis of SLE but can be the initial presentation of lupus in approximately 20%. DAH should be suspected in lupus patient presenting with new pulmonary infiltrates, decline in hemoglobin, hemoptysis, dyspnea, hypoxemia, and increase in carbon monoxide diffusion capacity. Radiographic evidence of bilateral pulmonary alveolar infiltrates that are usually perihilar or basilar with sparing of apices is seen. DAH can often mimic clinically and radiologically severe pneumonia or ARDS. Treatment includes high-dose corticosteroids, cyclophosphamide, and plasmapheresis. We report a case of diffuse alveolar hemorrhage complicating SLE flare-up in a male patient.

  8. Premenstrual Exacerbation of Life-Threatening Asthma: Effect of Gonadotrophin Releasing Hormone Analogue Therapy

    Directory of Open Access Journals (Sweden)

    Alun L Edwards

    1996-01-01

    Full Text Available Variability in the severity of asthma during various phases of the menstrual cycle has been frequently suspected. However, the hormonal changes that might affect mediators of bronchospasm have yet to be elucidated. The case of a 41-year-old woman suffering from longstanding asthma with life-threatening exacerbations is reported. The patient was treated with buserelin, a gonadotropin releasing hormone (GnRH analogue, which created a temporary chemical menopause and thus permitted diagnosis of a premenstrual exacerbation of asthma and offered insight into potential therapy. GnRH analogues may therefore be of value in assessing women with severe asthma suspected to vary with the menstrual cycle. The addition of estrogens and progestins at the same time as treatment with GnRH analogue may be of value in determining the role of these hormones in the pathogenesis of menstrually related exacerbations of asthma.

  9. Penile calciphylaxis: a life-threatening condition successfully treated with sodium thiosulfate.

    Science.gov (United States)

    Sandhu, Gagangeet; Gini, Marcelo Barrios; Ranade, Aditi; Djebali, David; Smith, Steven

    2012-01-01

    Calciphylaxis or calcific uremic arteriolopathy is a life-threatening condition that predominantly affects patients with end-stage renal disease on hemodialysis. A prevalence of up to 4% and a 6-month mortality rate of up to 80% have been reported in those with proximal disease (thighs, abdomen wall, and buttocks). Penile calciphylaxis is very rare but has a mortality rate of 69% within 6 months. Its treatment is controversial. For small lesions, conservative treatment with local wound care and debridement may suffice. Partial or complete penectomy may be needed for more extensive lesions, and especially those associated with signs of local infection. In addition to surgical intervention, as with any other case of calcific uremic arteriolopathy, the cornerstones of therapy should be to keep serum phosphorus sodium thiosulfate was used in addition to the standard medical and surgical therapy. Two months after surgery, the patient's wound completely healed and he has experienced no new lesions over the past 11 months.

  10. Endoclipping treatment of life-threatening rectal bleeding after prostate biopsy

    Institute of Scientific and Technical Information of China (English)

    Panagiotis Katsinelos,; Jannis Kountouras,; Georgios Dimitriadis,; Grigoris Chatzimavroudis,; Christos Zavos,; Ioannis Pilpilidis,; George Paroutoglou,; George Germanidis,; Kostas Mimidis

    2009-01-01

    Rectal bleeding is frequently seen in patients undergoing transrectal ultrasound (TRUS)-guided multiple biopsy of the prostate, but is usually mild and stops spontaneously. We report what is believed to be the first case of life-threatening rectal bleeding following this procedure, which was successfully treated by endoscopic intervention through placement of three clips on the sites of bleeding. This case emphasizes endoscopic intervention associated with endoclipping as a safe and effective method to achieve hemostasis in massive rectal bleeding after prostate biopsy. Additionally, current data on the complications of the TRUS-guided multiple biopsy of the prostate and the options for treating fulminant rectal bleeding, a consequence of this procedure, are described.

  11. Life threatening biphasic adverse reactions to desmopressin: case report and review of the literature.

    Science.gov (United States)

    Wang, Lijun; Chen, Ruijun; Tian, Fang; Wang, Wei; Wang, Li; Yu, Baojun; Huang, Xianwen; Zhang, Yuehui; Su, Shengyuan; Ma, Guangnian; Wang, Kaichen

    2016-08-01

    Treatment with desmopressin diacetate arginine vasopressin (DDAVP) and its withdrawal are associated with side effects. We present a rare case of severe biphasic adverse reactions induced by DDAVP and its withdrawal in a 63-year-old female patient. A lump in the left axillary region was biopsied, and she received DDAVP after surgery. The following day, she lost consciousness, with foaming at the mouth and seizures. Hypotonic encephalopathy was considered. DDAVP was ceased, and she received electrolytes. On day 1, she displayed low blood pressure and increased urine output. She received DDAVP and dopamine as well as electrolytes. The patient was ambulatory on day 7 and was discharged without brain abnormalities on MRI. In conclusion, severe hyponatremia induced by DDAVP and massive polyuria and hypovolemic shock induced by DDAVP withdrawal are life-threatening conditions. This case underlines the need to be vigilant when administering DDAVP and to monitor for any side effects. PMID:27142268

  12. Severe Sepsis Associated with Lemierre’s Syndrome: A Rare but Life-Threatening Disease

    Directory of Open Access Journals (Sweden)

    Audrey Tawa

    2016-01-01

    Full Text Available Background. The incidence of Lemierre’s syndrome has increased in the past decade. This posttonsillitis complication may be life threatening. Case Presentation. A 19-year-old patient was admitted to Surgical Intensive Care Unit of a French University Hospital for high fever, low blood pressure, and haemoptysis following a sore throat episode. Blood analysis revealed a thrombopenia, an acute renal failure, and an elevated lactate serum. Fusobacterium necrophorum was found in blood cultures. Computed tomography of the neck and lungs confirmed the diagnosis of Lemierre’s syndrome: pleural effusions, bilateral lung infiltrates, and an internal jugular vein thrombosis. Fluid administration and antibiotic treatment were quickly initiated. Patient left the unit four days after his admission without any organ dysfunction. Conclusion. Lemierre’s syndrome may lead to multiorgan dysfunction and should be rapidly identified.

  13. Life-threatening intoxication with methylene bis(thiocyanate: clinical picture and pitfalls. A case report

    Directory of Open Access Journals (Sweden)

    Schnuelle Peter

    2006-04-01

    Full Text Available Abstract Background Methylene bis(thiocyanate (MBT is a microbiocidal agent mainly used in industrial water cooling systems and paper mills as an inhibitor of algae, fungi, and bacteria. Case presentation We describe the first case of severe intoxication following inhalation of powder in an industrial worker. Profound cyanosis and respiratory failure caused by severe methemoglobinemia developed within several minutes. Despite immediate admission to the intensive care unit, where mechanical ventilation and hemodialysis for toxin elimination were initiated, multi-organ failure involving liver, kidneys, and lungs developed. While liver failure was leading, the patient was successfully treated with the MARS (molecular adsorbent recirculating system procedure. Conclusion Intoxication with MBT is a potentially life-threatening intoxication causing severe methemoglobinemia and multi-organ failure. Extracorporeal liver albumin dialysis (MARS appears to be an effective treatment to allow recovery of hepatic function.

  14. Renal parenchymal histopathology predicts life-threatening chronic kidney disease as a result of radical nephrectomy.

    Science.gov (United States)

    Sejima, Takehiro; Honda, Masashi; Takenaka, Atsushi

    2015-01-01

    The preoperative prediction of post-radical nephrectomy renal insufficiency plays an important role in the decision-making process regarding renal surgery options. Furthermore, the prediction of both postoperative renal insufficiency and postoperative cardiovascular disease occurrence, which is suggested to be an adverse consequence caused by renal insufficiency, contributes to the preoperative policy decision as well as the precise informed consent for a renal cell carcinoma patient. Preoperative nomograms for the prediction of post-radical nephrectomy renal insufficiency, calculated using patient backgrounds, are advocated. The use of these nomograms together with other types of nomograms predicting oncological outcome is beneficial. Post-radical nephrectomy attending physicians can predict renal insufficiency based on the normal renal parenchymal pathology in addition to preoperative patient characteristics. It is suggested that a high level of global glomerulosclerosis in nephrectomized normal renal parenchyma is closely associated with severe renal insufficiency. Some studies showed that post-radical nephrectomy severe renal insufficiency might have an association with increased mortality as a result of cardiovascular disease. Therefore, such pathophysiology should be recognized as life-threatening, surgically-related chronic kidney disease. On the contrary, the investigation of the prediction of mild post-radical nephrectomy renal insufficiency, which is not related to adverse consequences in the postoperative long-term period, is also promising because the prediction of mild renal insufficiency might be the basis for the substitution of radical nephrectomy for nephron-sparing surgery in technically difficult or compromised cases. The deterioration of quality of life caused by post-radical nephrectomy renal insufficiency should be investigated in conjunction with life-threatening matters.

  15. Genome-wide association of implantable cardioverter-defibrillator activation with life-threatening arrhythmias.

    Directory of Open Access Journals (Sweden)

    Sarah S Murray

    Full Text Available OBJECTIVES: To identify genetic factors that would be predictive of individuals who require an implantable cardioverter-defibrillator (ICD, we conducted a genome-wide association study among individuals with an ICD who experienced a life-threatening arrhythmia (LTA; cases vs. those who did not over at least a 3-year period (controls. BACKGROUND: Most individuals that receive implantable cardioverter-defibrillators never experience a life-threatening arrhythmia. Genetic factors may help identify who is most at risk. METHODS: Patients with an ICD and extended follow-up were recruited from 34 clinical sites with the goal of oversampling those who had experienced LTA, with a cumulative 607 cases and 297 controls included in the analysis. A total of 1,006 Caucasian patients were enrolled during a time period of 13 months. Arrhythmia status of 904 patients could be confirmed and their genomic data were included in the analysis. In this cohort, there were 704 males, 200 females, and the average age was 73.3 years. We genotyped DNA samples using the Illumina Human660 W Genotyping BeadChip and tested for association between genotype at common variants and the phenotype of having an LTA. RESULTS AND CONCLUSIONS: We did not find any associations reaching genome-wide significance, with the strongest association at chromosome 13, rs11856574 at P = 5×10⁻⁶. Loci previously implicated in phenotypes such as QT interval (measure of the time between the start of the Q wave and the end of the T wave as measured by electrocardiogram were not found to be significantly associated with having an LTA. Although powered to detect such associations, we did not find common genetic variants of large effect associated with having a LTA in those of European descent. This indicates that common gene variants cannot be used at this time to guide ICD risk-stratification. TRIAL REGISTRATION: ClinicalTrials.gov NCT00664807.

  16. The emergency department ECG and immediately life-threatening complications in initially uncomplicated suspected myocardial ischemia.

    Science.gov (United States)

    Zalenski, R J; Sloan, E P; Chen, E H; Hayden, R F; Gold, I W; Cooke, D

    1988-03-01

    The emergency physician's disposition of patients with suspected myocardial ischemia is currently debated; some physicians believe that a subgroup of patients can be managed safely outside the coronary care unit. Clinical predictors are needed in assessing the patient with suspected myocardial ischemia to help identify this subgroup. Through a retrospective cohort study, we investigated the value of the initial emergency department ECG in discriminating between chest pain patients with low and high risk for immediately life-threatening complications. Two hundred eleven initially uncomplicated consecutive coronary care unit admissions with suspected unstable angina or myocardial infarction were studied. Patient outcome, including the incidence of myocardial infarction, complications, and mechanical and pharmacologic interventions, was reviewed. Immediately life-threatening complications included ventricular fibrillation, ventricular tachycardia, shock, 2 degrees and 3 degrees block, and death. Mechanical interventions included electrocardioversion or defibrillation, endotracheal intubation, intra-aortic balloon pump, Swan-Ganz catheter, or pacemaker insertion. Pressors, antiarrhythmics, and vasodilators were the reviewed pharmacologic interventions. A positive ECG was defined by the presence of ST elevation or depression, T wave inversion, left ventricular hypertrophy, left bundle branch block, paced rhythm, or new Q waves. All other ECG interpretations were considered negative. Patients were divided into two groups based on this initial emergency physician ECG interpretation and their complication incidences compared. Of the 211 patients, 96 had a positive ECG; 115 had negative ECGs. Patients with positive ECGs were older, had a greater history and concurrent incidence of myocardial infarction, and more complications and intensive interventions.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:3345014

  17. No apparent superluminal motion in the first-known jetted tidal disruption event Swift J1644+5734

    CERN Document Server

    Yang, J; Gurvits, L I; Campbell, R M; Giannios, D; An, T; Komossa, S

    2016-01-01

    The first-known tidal disruption event (TDE) with strong evidence for a relativistic jet -- based on extensive multi-wavelength campaigns -- is Swift J1644+5734. In order to directly measure the apparent speed of the radio jet, we performed very long baseline interferometry (VLBI) observations with the European VLBI network (EVN) at 5 GHz. Our observing strategy was to identify a very nearby and compact radio source with the real-time e-EVN, and then utilise this source as a stationary astrometry reference point in the later five deep EVN observations. With respect to the in-beam source FIRST J1644+5736, we have achieved a statistical astrometric precision about 12 micro-arcsecond (68 % confidence level) per epoch. This is one of the best phase-referencing measurements available to date. No proper motion has been detected in the Swift J1644+5734 radio ejecta. We conclude that the apparent average ejection speed between 2012.2 and 2015.2 was less than 0.3c with a confidence level of 99 %. This tight limit is d...

  18. No apparent superluminal motion in the first-known jetted tidal disruption event Swift J1644+5734

    Science.gov (United States)

    Yang, J.; Paragi, Z.; van der Horst, A. J.; Gurvits, L. I.; Campbell, R. M.; Giannios, D.; An, T.; Komossa, S.

    2016-10-01

    The first-known tidal disruption event (TDE) with strong evidence for a relativistic jet - based on extensive multiwavelength campaigns - is Swift J1644+5734. In order to directly measure the apparent speed of the radio jet, we performed very long baseline interferometry (VLBI) observations with the European VLBI network (EVN) at 5 GHz. Our observing strategy was to identify a very nearby and compact radio source with the real-time e-EVN, and then utilize this source as a stationary astrometry reference point in the later five deep EVN observations. With respect to the in-beam source FIRST J1644+5736, we have achieved a statistical astrometric precision about 12 μas (68 per cent confidence level) per epoch. This is one of the best phase-referencing measurements available to date. No proper motion has been detected in the Swift J1644+5734 radio ejecta. We conclude that the apparent average ejection speed between 2012.2 and 2015.2 was less than 0.3c with a confidence level of 99 per cent. This tight limit is direct observational evidence for either a very small viewing angle or a strong jet deceleration due to interactions with a dense circum-nuclear medium, in agreement with some recent theoretical studies.

  19. Citric acid as the last therapeutic approach in an acute life-threatening metabolic decompensation of propionic acidaemia.

    Science.gov (United States)

    Siekmeyer, Manuela; Petzold-Quinque, Stefanie; Terpe, Friederike; Beblo, Skadi; Gebhardt, Rolf; Schlensog-Schuster, Franziska; Kiess, Wieland; Siekmeyer, Werner

    2013-01-01

    The tricarboxylic acid (TCA) cycle represents the key enzymatic steps in cellular energy metabolism. Once the TCA cycle is impaired in case of inherited metabolic disorders, life-threatening episodes of metabolic decompensation and severe organ failure can arise. We present the case of a 6 ½-year-old girl with propionic acidaemia during an episode of acute life-threatening metabolic decompensation and severe lactic acidosis. Citric acid given as an oral formulation showed the potential to sustain the TCA cycle flux. This therapeutic approach may become a treatment option in a situation of acute metabolic crisis, possibly preventing severe disturbance of energy metabolism.

  20. Brazilian network for the surveillance of maternal potentially life threatening morbidity and maternal near-miss and a multidimensional evaluation of their long term consequences

    Directory of Open Access Journals (Sweden)

    Surita Fernanda G

    2009-09-01

    Full Text Available Abstract Background It has been suggested that the study of women who survive life-threatening complications related to pregnancy (maternal near-miss cases may represent a practical alternative to surveillance of maternal morbidity/mortality since the number of cases is higher and the woman herself is able to provide information on the difficulties she faced and the long-term repercussions of the event. These repercussions, which may include sexual dysfunction, postpartum depression and posttraumatic stress disorder, may persist for prolonged periods of time, affecting women's quality of life and resulting in adverse effects to them and their babies. Objective The aims of the present study are to create a nationwide network of scientific cooperation to carry out surveillance and estimate the frequency of maternal near-miss cases, to perform a multicenter investigation into the quality of care for women with severe complications of pregnancy, and to carry out a multidimensional evaluation of these women up to six months. Methods/Design This project has two components: a multicenter, cross-sectional study to be implemented in 27 referral obstetric units in different geographical regions of Brazil, and a concurrent cohort study of multidimensional analysis. Over 12 months, investigators will perform prospective surveillance to identify all maternal complications. The population of the cross-sectional component will consist of all women surviving potentially life-threatening conditions (severe maternal complications or life-threatening conditions (the maternal near miss criteria and maternal deaths according to the new WHO definition and criteria. Data analysis will be performed in case subgroups according to the moment of occurrence and determining cause. Frequencies of near-miss and other severe maternal morbidity and the association between organ dysfunction and maternal death will be estimated. A proportion of cases identified in the cross

  1. Life-threatening angio-oedema after the first dose of an ACE inhibitor-not an anaphylactic reaction

    DEFF Research Database (Denmark)

    Krogh Nielsen, Troels; Bygum, Anette; Rye Rasmussen, Eva

    2016-01-01

    We present a case of a 60-year-old Caucasian woman, with no prior history of swellings, who was admitted to a hospital due to life-threatening angio-oedema. She had, the previous day, been prescribed an ACE inhibitor for her essential hypertension. She had taken one tablet at night-time, and awoke...

  2. Trends in a Life Threatening Condition: Morbid Obesity in Dutch, Turkish and Moroccan Children in The Netherlands

    NARCIS (Netherlands)

    Dommelen, P. van; Schönbeck, Y.; Buuren, S. van; Hirasing, R.

    2014-01-01

    Background: Morbid obesity can be a life threatening condition. The aim of our study is to assess the trend in morbid obesity in The Netherlands among children of Dutch origin since 1980, and among children of Turkish and Moroccan origin since 1997. Methods and Findings: Cross-sectional height and w

  3. Trends in a life threatening condition : Morbid obesity in Dutch, Turkish and Moroccan children in the Netherlands

    NARCIS (Netherlands)

    Van Dommelen, Paula; Schönbeck, Yvonne; Van Buuren, Stef; HiraSing, Remy A.

    2014-01-01

    Background: Morbid obesity can be a life threatening condition. The aim of our study is to assess the trend in morbid obesity in The Netherlands among children of Dutch origin since 1980, and among children of Turkish and Moroccan origin since 1997. Methods and Findings: Cross-sectional height and w

  4. Awareness about a Life-Threatening Condition: Ectopic Pregnancy in a Network for Surveillance of Severe Maternal Morbidity in Brazil

    OpenAIRE

    Edilberto Alves Rocha Filho; Danielly Scaranello Santana; Jose Guilherme Cecatti; Maria Laura Costa; Samira Maerrawe Haddad; Mary Angela Parpinelli; Maria Helena de Sousa; Rodrigo Soares Camargo; Rodolfo de Carvalho Pacagnella; Fernanda Garanhani Surita; Joao Luiz Pinto e Silva

    2014-01-01

    Objective. To assess occurrence of severe maternal complications associated with ectopic pregnancy (EP). Method. A multicenter cross-sectional study was conducted, with prospective surveillance of potentially life-threatening conditions (PLTC), maternal near miss (MNM), and maternal death (MD). EP complications, patient sociodemographic/obstetric characteristics, and conditions of severity management were assessed, estimating prevalence ratios with respective 95% CI. Factors independently ass...

  5. [A Case of Life-Threatening Angioedema Occurred During Prolonged Angiotensin-Converting Enzyme Inhibitor Treatment].

    Science.gov (United States)

    Nakamura, Rintaro; Nihei, Shun-Ichi; Arai, Hideaki; Nagata, Keiji; Isa, Yasuki; Harayama, Nobuya; Aibara, Keiji; Kamochi, Msayuki

    2016-03-01

    Although angiotensin-converting enzyme (ACE) inhibitors are widely used as the first choice drug for treating hypertension, we have only a superficial understanding of their relationship to angioedema. We report a case of life-threatening angioedema. The case was a 60-year-old man who had been taking an ACE inhibitor for hypertension for 11 years. He visited his home doctor for dyspnea, and tongue and neck swelling. He was transported to our hospital because of the possibility of airway obstruction. On admission, his tongue and neck swelling became more severe. We performed an intubation using an endoscope and started airway management. We also stopped his ACE inhibitor. The severe tongue and neck swelling improved gradually and he was extubated on day 3. On the fifth day he was discharged. We diagnosed angioedema caused by an ACE inhibitor. Although the risk of airway obstruction with ACE inhibitors is acknowledged, we have only a superficial understanding of how prolonged ACE inhibitor treatment induces angioedema. So we should consider angioedema in cases of taking ACE inhibitors, especially in cases of prolonged treatment. PMID:26972946

  6. [Life-threatening injuries of the subcutaneous ventral abdominal veins in dairy cows].

    Science.gov (United States)

    Schmid, B; Muggli, E; Schmid, T; Nuss, K

    2011-05-01

    Injuries of the superficial veins on the ventral abdomen of dairy cows can result in life-threatening haemorrhage. Treatment of these injuries can be difficult because of the characteristics of the veins. Five cows aged 6.5 to 12 years were referred to the Animal Hospitale Zurich, because of intermittent haemorrhage from a ventral abdominal vein. Four of the cows were near term and one had calved two weeks before referral. Intermittent bleeding was seen from the highly convoluted and dilated subcutaneous tributaries to the cranial superficial epigastric vein (milk vein). The haematocrit of 2 cows was markedly lower than normal. Emergency slaughter of one of the cows was carried out because of advanced age. The other 4 cows were sedated and after application of local anaesthetic, the wounds were debrided and sutured. Two of the cows required a blood transfusion before being operated. There were no postoperative complications. This type of injury seems to occur predominantly in pluriparous dairy cows close to term, in which the tributaries to the milk vein have undergone varicose changes. Treatment should consist of surgical resection of the injured tissue and suturing of the venous wall, subcutaneous tissues and skin.

  7. An Interesting Case of Life-Threatening Hypercalcemia Secondary to Atypical Parathyroid Adenoma versus Parathyroid Carcinoma

    Directory of Open Access Journals (Sweden)

    Ankur Mishra

    2014-01-01

    Full Text Available Context. Severe hypercalcemia is a life-threatening condition. Atypical parathyroid adenoma and parathyroid carcinomas are uncommon causes which can be difficult to differentiate. Objective. We report a case of a 36-year-old male with very high serum calcium due to a possible atypical parathyroid adenoma versus parathyroid carcinoma. Case Illustration. A serum calcium level of 23.2 mg/dl was noted on admission. He was initially treated with IV hydration, pamidronate, and salmon calcitonin to lower his calcium levels. He also underwent a surgical en bloc resection of parathyroid mass. Pathology showed a mixed picture consistent with possible atypical adenoma versus parathyroid carcinoma. However, due to the possible involvement of the recurrent laryngeal nerve, parathyroid carcinoma was more likely. Also after operation the patient developed hungry bones syndrome and his calcium was replaced vigorously. He continues to be on calcium, vitamin D, and calcitriol supplementation. Results. A review of the literature was conducted to identify previous studies pertaining to parathyroid adenomas and parathyroid cancer. Conclusion. We thereby conclude that hypercalcemia requires very careful monitoring especially after operation. Also it can be very difficult to distinguish between atypical parathyroid adenomas and parathyroid carcinomas as in our case and no clear cut guidelines yet exist to differentiate the two based on histology.

  8. Treatment of life-threatening hypercapnia with isoflurane in an infant with status asthmaticus.

    Science.gov (United States)

    Masuda, Yoshiki; Tatsumi, Hiroomi; Goto, Kyoko; Imaizumi, Hitoshi; Yoshida, Shin-ichiro; Kimijima, Tomohiko; Yamakage, Michiaki

    2014-08-01

    We encountered a 2-year-old child with life-threatening hypercapnia, with a PaCO(2) of 238 mm Hg and severe respiratory and metabolic acidosis, due to status asthmaticus that was refractory to steroid and bronchodilator therapy. Suspecting ventilatory failure and excessive ventilation-induced obstructive shock, we started respiratory physiotherapy in synchrony with her respiration, to facilitate exhalation from her over-inflated lungs. Isoflurane inhalation was commenced in preparation for extracorporeal circulation, to reduce the hypercapnia. The combination of respiratory physiotherapy and isoflurane inhalation resulted in a rapid decrease in ventilatory resistance and PaCO(2) levels within a few minutes, with recovery of consciousness within 60 min. Isoflurane inhalation was gradually discontinued and steroid and aminophylline therapy were commenced. The patient recovered completely without any recurrence of her bronchospasm and without any residual neurological deficits. In our patient with a severe asthmatic attack, decreased exhalation secondary to asthma and overventilation during artificial ventilation resulted in overinflation of the lungs, which in turn led to cerebral edema and obstructive cardiac failure. The favorable outcome in this case was due to the short duration of hypercapnia. Hence, we conclude that the duration of hypercapnia is an important determinant of the morbidity and mortality of status asthmaticus-induced severe hypercapnia. PMID:24310852

  9. Pulmonary hemorrhage complicating radiofrequency ablation, from mild hemoptysis to life-threatening pattern

    Energy Technology Data Exchange (ETDEWEB)

    Nour-Eldin, Nour-Eldin A.; Naguib, Nagy N.N.; Mack, Martin; Abskharon, John E.; Vogl, Thomas J. [Johann Wolfgang Goethe-University Hospital, Institute for Diagnostic and Interventional Radiology, Frankfurt am Main (Germany)

    2011-01-15

    To assess risk factors and the extent of pulmonary hemorrhage complicating radiofrequency ablation (RFA) of pulmonary neoplasms. This retrospective study involved 248 ablation sessions for lung tumors (20 primary lesions and 228 metastatic lesions) in 164 patients (mean age 59.7 years, SD: 10.2). Both unipolar and bipolar radiofrequency systems were used under CT fluoroscopic guidance. Extent and underlying factors associated with development of pulmonary hemorrhage were analyzed. Incidence of intra-parenchymal pulmonary hemorrhage, pleural effusion, and hemoptysis were 17.7% (44/248 sessions), 4% (8/248 sessions), and 16.1% (40/248 sessions), respectively. Death because of massive bleeding occurred in one session (0.4%). Significant risk factors associated with intra-parenchymal hemorrhage included: lesions of <1.5 cm diameter (P = 0.007); basal and middle lung zone lesions (P = 0.026); increased needle track distance traversing the lung parenchyma >2.5 cm (P = 0.0017); traversing pulmonary vessels in the track of ablation (P < 0.001); and the use of multi-tined electrodes (P = 0.004). Concomitant incidence of pulmonary hemorrhage and pneumothorax was 29.2% (14/48 sessions). While typically safe, RFA of pulmonary neoplasms can result in pulmonary hemorrhage ranging from mild to life-threatening. Management of this complication is mainly preventive through adequate patient selection for ablation therapy and exclusion of technically avoidable risk factors. (orig.)

  10. A glucagon analog chemically stabilized for immediate treatment of life-threatening hypoglycemia.

    Science.gov (United States)

    Chabenne, Joseph; Chabenne, Maria Dimarchi; Zhao, Yan; Levy, Jay; Smiley, David; Gelfanov, Vasily; Dimarchi, Richard

    2014-06-01

    For more than half a century glucagon has been used as a critical care medicine in the treatment of life-threatening hypoglycemia. It is commercially supplied as a lyophilized powder intended to be solubilized in dilute aqueous hydrochloric acid immediately prior to administration. We have envisioned a "ready-to-use" glucagon as a drug of more immediate and likely use. Through a series of iterative changes in the native sequence we have identified glucagon analogs of appreciably enhanced aqueous solubility at physiological pH, and of chemical stability suitable for routine medicinal use. The superior biophysical properties were achieved in part through adjustment of the isoelectric point by use of a C-terminal Asp-Glu dipeptide. The native glutamines at positions 3, 20 and 24 as well as the methionine at 27 were substituted with amino acids of enhanced chemical stability, as directed by a full alanine scan of the native hormone. Of utmost additional importance was the dramatically enhanced stability of the peptide when Ser16 was substituted with alpha,aminoisobutyric acid (Aib), a substitution that stabilizes peptide secondary structure. The collective set of changes yield glucagon analogs of comparable in vitro and in vivo biological character to native hormone but with biophysical properties much more suitable for clinical use. PMID:24749059

  11. Novel biomarkers for risk stratification and identification of life-threatening cardiovascular disease: troponin and beyond.

    Science.gov (United States)

    Razzouk, Louai; Fusaro, Mario; Esquitin, Ricardo

    2012-05-01

    Chest pain and other symptoms that may represent acute coronary syndromes (ACS) are common reasons for emergency department (ED) presentations, accounting for over six million visits annually in the United States [1]. Chest pain is the second most common ED presentation in the United States. Delays in diagnosis and inaccurate risk stratification of chest pain can result in serious morbidity and mortality from ACS, pulmonary embolism (PE), aortic dissection and other serious pathology. Because of the high morbidity, mortality, and liability issues associated with both recognized and unrecognized cardiovascular pathology, an aggressive approach to the evaluation of this patient group has become the standard of care. Clinical history, physical examination and electrocardiography have a limited diagnostic and prognostic role in the evaluation of possible ACS, PE, and aortic dissection, so clinicians continue to seek more accurate means of risk stratification. Recent advances in diagnostic imaging techniques particularly computed-tomography of the coronary arteries and aorta, have significantly improved our ability to diagnose life-threatening cardiovascular disease. In an era where health care utilization and cost are major considerations in how disease is managed, it is crucial to risk-stratify patients quickly and efficiently. Historically, biomarkers have played a significant role in the diagnosis and risk stratification of several cardiovascular disease states including myocardial infarction, congestive heart failure, and pulmonary embolus. Multiple biomarkers have shown early promise in answering questions of risk stratification and early diagnosis of cardiovascular pathology however many do not yet have wide clinical availability. The goal of this review will be to discuss these novel biomarkers and describe their potential role in direct patient care. PMID:22708908

  12. Life-threatening hyperkalemia following zoledronic acid infusion for Paget's disease: a case report

    Directory of Open Access Journals (Sweden)

    Naysmith Morag

    2011-08-01

    Full Text Available Abstract Introduction Zoledronic acid is a highly effective treatment in Paget's disease for persistent bone pain and prevention of further progression of the disease. The commonest electrolyte abnormality is hypocalcemia. To the best of our knowledge this is the first case of hyperkalemia secondary to zoledronic acid to be published in the world literature. The commonest arrhythmia related to zoledronic acid is atrial fibrillation. Case presentation We describe the case of an 80-year-old Caucasian man, with a history of ischemic heart disease, who had an in-hospital cardiac arrest related to hyperkalemia. Increasing potassium levels were noted following his first zoledronic acid infusion for symptomatic control of bone pain secondary to Paget's disease. Our patient suffered a cardiac arrest 10 days following the zoledronic acid infusion. Our patient's biochemistry and electrocardiogram output were monitored until his death 26 days after his cardiac arrest. Our patient developed paroxysmal atrial fibrillation in the post-resuscitation period and there was persistent hyperkalemia that required prolonged treatment with calcium resonium. All other possible causes of hyperkalemia were excluded. Conclusion In our patient's case persistent hyperkalemia and life-threatening arrhythmias were associated with use of zoledronic acid. These side effects have not been reported before and the causative mechanism is far from clear as there are no obvious systemic effects of zoledronic acid. The combination of zoledronic acid with predisposing factors such as structural heart disease might account for the clinical picture we witnessed. As a result, electrolyte monitoring should be adopted early in zoledronic acid use. Further studies are required to elucidate the underlying mechanism of hyperkalemia and identify the target group of patients where zoledronic acid can be safely administered. Great caution is advised in patients with underlying heart conditions.

  13. Near-death-like experiences without life-threatening conditions or brain disorders: a hypothesis from a case report

    Directory of Open Access Journals (Sweden)

    Enrico eFacco

    2012-11-01

    Full Text Available Near-death experiences (NDEs are profound psychic experiences commonly occurring in life-threatening conditions. They include feeling a sense of peace, of seeing a bright light, encountering deceased relatives or religious figures, and of transcending space and time. To explain them, it has been suggested that they stem from brain disorders and/or psychological reactions to approaching death, a sort of wishful thinking in response to the perceived threat.This is a report on a case with most of the features typical of NDEs except that it occurred entirely without any life-threatening conditions. This evidence is theoretically incompatible with either of the above hypotheses, suggesting that a broader interpretation of the phenomenon is needed.

  14. [Structural requirements for the management of patients with highly contagious life-threatening infectious diseases: update 2015].

    Science.gov (United States)

    Grünewald, Thomas

    2015-07-01

    The care of highly contagious life-threatening infectious diseases (HLID) requires specialized treatment facilities that are capable of strict isolation measures and appropriate medical treatment. The German approach to the management of these diseases, which is maintained by the Permanent Working Group of Medical Competence and Treatment Centers for Highly Contagious and Life-Threatening Diseases (STAKOB) is adjusted in the present publication with regards to recent experiences and upcoming needs. Clear synergies in using infrastructures and bundling of resources have led to similar efforts at the European level. The German concept, therefore, has a pioneering role. This update is intended to improve professional patient care and also minimize the risk of disease spread and transmission.

  15. Life threatening intracerebral haemorrhage following saw- scaled viper (Echis carinatus) envenoming-authenticated case report from Sri Lanka

    OpenAIRE

    Fonseka, Chathuranga Lakmal; jeevagan, Vijayabala; Gnanathasan, Christeine Ariaranee

    2013-01-01

    Background Echis carinatus (Saw scaled viper {SSV}) is a venomous snake found in the parts of Middle East and Central Asia. SSV envenoming is characterized by local swelling and coagulopathy. Various bleeding manifestations are commonly seen with SSV envenoming. In contrast to other part of Asia, saw scale viper envenoming has not been reported to cause life threatening haemorrhagic manifestations in Sri Lanka. Case presentation We report a 19 years old healthy boy who developed massive left ...

  16. Barriers to emergency obstetric care services: accounts of survivors of life threatening obstetric complications in Malindi District, Kenya

    OpenAIRE

    Echoka, Elizabeth; Makokha, Anselimo; Dubourg, Dominique; Kombe, Yeri; Nyandieka, Lillian; Byskov, Jens

    2014-01-01

    Introduction Pregnancy-related mortality and morbidity in most low and middle income countries can be reduced through early recognition of complications, prompt access to care and appropriate medical interventions following obstetric emergencies. We used the three delays framework to explore barriers to emergency obstetric care (EmOC) services by women who experienced life threatening obstetric complications in Malindi District, Kenya. Methods A facility-based qualitative study was conducted ...

  17. Non-invasive tools for the diagnosis of potentially life-threatening gynaecological emergencies : a systematic review

    OpenAIRE

    Viola Polena; Cyrille Huchon; Catalina Varas Ramos; Roman Rouzier; Alexandre Dumont; Arnaud Fauconnier

    2015-01-01

    Objective To identify non- invasive tools for diagnosis of the major potentially life-threatening gynaecological emergencies (G-PLEs) reported in previous studies, and to assess their diagnostic accuracy. Methods MEDLINE; EMBASE; Cochrane Central Register of Controlled Trials (CENTRAL; The Cochrane Library) were searched to identify all eligible studies published in English or French between January 1990 and December 2012. Studies were considered eligible if they were primary diagnostic studi...

  18. Flow Cytometry as a Diagnostic Tool in the Early Diagnosis of Aggressive Lymphomas Mimicking Life-Threatening Infection

    Directory of Open Access Journals (Sweden)

    Nikolaos J. Tsagarakis

    2011-01-01

    Full Text Available Aggressive lymphomas can present with symptoms mimicking life-threatening infection. Flow cytometry (FC is usually recommended for the classification and staging of lymphomas in patients with organomegaly and atypical cells in effusions and blood, after the exclusion of other possible diagnoses. FC may also have a place in the initial diagnostic investigation of aggressive lymphoma. Three cases are presented here of highly aggressive lymphomas in young adults, which presented with the clinical picture of fever of unknown origin (FUO in patients severely ill. All followed a life-threatening clinical course, and two developed the hemophagocytic syndrome (HPS, but microbiological, immunological, and morphological evaluation and immunohistochemistry (IHC failed to substantiate an early diagnosis. FC was the technique that provided conclusive diagnostic evidence of lymphoma, subsequently verified by IHC. Our experience with these three cases highlights the potential role of FC as an adjunct methodology in the initial assessment of possible highly aggressive lymphoma presenting with the signs and symptoms of life-threatening infection, although the definitive diagnosis should be established by biopsy. In such cases, FC can contribute to the diagnosis of lymphoma, independently of the presence of HPS.

  19. Transarterial microcatheter glue embolization of the bronchial artery for life-threatening hemoptysis: Technical and clinical results

    Energy Technology Data Exchange (ETDEWEB)

    Baltacioglu, Feyyaz [Marmara University School of Medicine, Department of Radiology, Istanbul (Turkey)], E-mail: fbaltaci@yahoo.com; Cimsit, Nuri Cagatay [Marmara University School of Medicine, Department of Radiology, Istanbul (Turkey)], E-mail: cagataycimsit@gmail.com; Bostanci, Korkut [Marmara University School of Medicine, Department of Thoracic Surgery, Istanbul (Turkey)], E-mail: kbostanci@marmara.edu.tr; Yueksel, Mustafa [Marmara University School of Medicine, Department of Thoracic Surgery, Istanbul (Turkey)], E-mail: myuksel@marmara.edu.tr; Kodalli, Nihat [Marmara University School of Medicine, Department of Radiology, Istanbul (Turkey)], E-mail: nihatkodalli@yahoo.com

    2010-02-15

    Objectives: To report our experience with transarterial glue embolization of the bronchial artery for life-threatening hemoptysis. Materials and methods: Twenty-five patients underwent bronchial artery embolization, using coaxial microcatheter technique, with a liquid agent, n-butyl-2-cyanoacrylate (NBCA), named glue, for life-threatening hemoptysis. The technical and clinical outcomes were followed in terms of immediate control of bleeding, recurrence of hemoptysis and complications of the procedure. Results: Four patients had acute hemoptysis when they were evaluated. The average number of arteries embolized per patient was 2.9. BAEs were successful in controlling hemoptysis immediately in all 25 patients (100%) and in 24 patients (96%) at 1 month follow-ups. One patient had recurrent hemoptysis on the tenth day after embolization. The follow-up time ranged from 2 to 63 months (mean 14 months). Six patients (25%) died all as a result of their disease process. Bleeding recurred in 3 patients after 30 days (7th, 11th, 12th months). One patient had vomitting attacks with dysphagia after the procedure that lasted 24 h. Three patients had transient thoracic pain lasting 3-5 days. There were no procedure related spinal or vascular complications. Conclusions: Glue embolization with microcatheter technique is a safe and effective treatment in cases of life-threatening hemoptysis with a very high rate of success and low rate of complications.

  20. Deficient supplies of drugs for life threatening diseases in an African community

    Directory of Open Access Journals (Sweden)

    Andrew Marit

    2007-06-01

    Full Text Available Abstract Background In Malawi essential drugs are provided free of charge to patients at all public health facilities in order to ensure equitable access to health care. The country thereby spends about 30% of the national health budget on drugs. In order to investigate the level of drug shortages and eventually find the reasons for the drugs shortages in Malawi, we studied the management of the drug supplies for common and life threatening diseases such as pneumonia and malaria in a random selection of health centres. Methods In July and August 2005 we visited eight out of a total of 37 health centres chosen at random in the Lilongwe District, Malawi. We recorded the logistics of eight essential and widely used drugs which according to the treatment guidelines should be available at all health centres. Five drugs are used regularly to treat pneumonia and three others to treat acute malaria. Out-of-stock situations in the course of one year were recorded retrospectively. We compared the quantity of each drug recorded on the Stock Cards with the actual stock of the drug on the shelves at the time of audit. We reviewed 8,968 Patient Records containing information on type and amount of drugs prescribed during one month. Results On average, drugs for treating pneumonia were out of stock for six months during one year of observation (median value 167 days; anti-malarial drugs were lacking for periods ranging from 42 to138 days. The cross-sectional audit was even more negative, but here too the situation was more positive for anti-malarial drugs. The main reason for the shortage of drugs was insufficient deliveries from the Regional Medical Store. Benzyl penicillin was in shortest supply (4% received. The median value for non-availability was 240 days in the course of a year. The supply was better for anti-malarial drugs, except for quinine injections (9 %. Only 66 % of Stock Card records of quantities received were reflected in Patient Records

  1. Bio-psychosocial determinants of time lost from work following non life threatening acute orthopaedic trauma

    Directory of Open Access Journals (Sweden)

    Ozanne-Smith Joan

    2010-01-01

    Full Text Available Abstract Background To determine factors predicting the duration of time away from work following acute orthopaedic non life threatening trauma Methods Prospective cohort study conducted at four hospitals in Victoria, Australia. The cohort comprised 168 patients aged 18-64 years who were working prior to the injury and sustained a range of acute unintentional orthopaedic injuries resulting in hospitalization. Baseline data was obtained by survey and medical record review. Multivariate Cox proportional hazards regression analysis was used to examine the association between potential predictors and the duration of time away from work during the six month study. The study achieved 89% follow-up. Results Of the 168 participants recruited to the study, 68% returned to work during the six month study. Multivariate Cox proportional hazards regression analysis identified that blue collar work, negative pain attitudes with respect to work, high initial pain intensity, injury severity, older age, initial need for surgery, the presence of co-morbid health conditions at study entry and an orthopaedic injury to more than one region were associated with extended duration away from work following the injury. Participants in receipt of compensation who reported high social functioning at two weeks were 2.58 times more likely to have returned to work than similar participants reporting low social functioning. When only those who had returned to work were considered, the participant reported reason for return to work " to fill the day" was a significant predictor of earlier RTW [RR 2.41 (95% C.I 1.35-4.30] whereas "financial security" and "because they felt able to" did not achieve significance. Conclusions Many injury-related and psycho social factors affect the duration of time away from work following orthopaedic injury. Some of these are potentially modifiable and may be amenable to intervention. Further consideration of the reasons provided by participants

  2. Clinical risk factors for life-threatening lower respiratory tract infections in children: a retrospective study in an urban city in Malaysia.

    Directory of Open Access Journals (Sweden)

    Anna Marie Nathan

    Full Text Available AIM: Lower respiratory tract infections (LRTIs are an important cause of morbidity and mortality, especially in low income countries. The aim of this study was to determine risk factors of life-threatening LRTIs in hospitalised children in Malaysia. METHODS: This retrospective study included children aged less than 18 years admitted for LRTIs over 13 months in a tertiary referral centre in Kuala Lumpur, Malaysia. Neonates, children with asthma and those with either no or a normal chest radiograph were excluded. Life-threatening infection was defined as that needing non-invasive ventilation or admission to the paediatric intensive care unit. Routine blood investigations and nasopharyngeal secretion results (bacterial and viral were obtained. Chest radiographs were reviewed by a designated radiologist. Environmental data (rainfall, particulate matter ≤ 10 µm [PM10] and air pollution index [API] was obtained from the respective government departments. RESULTS: Three hundred and ninety-one episodes of LRTIs were included. Viruses were implicated in 48.5% of LRTIs, with respiratory syncytial virus (RSV being detected in 44% of viral LRTIs. Forty-six (11.8% children had life-threatening disease and the overall mortality rate was 1.3% (5 children. RSV was detected in 26% of children with life-threatening LRTIs. In multivariate logistic regression, chronic lung disease, presenting history of apnoea and signs of hypoxia, was associated with life threatening LRTIs. Increased LRTI admissions were associated with low rainfall but not PM10 nor API. Of those on follow-up, 39% had persistent respiratory symptoms. CONCLUSION: One in nine children admitted with LRTI had a life-threatening LRTI. The aetiology was viral in almost half of admitted children. RSV was detected in a quarter of children with life-threatening LRTIs. Children who present with LRTIs and either have chronic lung disease, presenting history of apnoea or signs of hypoxia, should be

  3. Life-threatening rupture of a renal angiomyolipoma in a patient taking over-the-counter horse chestnut seed extract.

    LENUS (Irish Health Repository)

    Snow, Aisling

    2011-02-09

    BACKGROUND: Alternative medical therapies are increasingly being prescribed due to their good safety profile and perceived limited side effects. They are often unregulated and prescribed over the counter. One such medication is horse chestnut seed extract (HCSE), which is used for the treatment of chronic venous insufficiency and is known to affect blood coagulation. Angiomyolipoma (AML) is a benign fat-containing mesenchymal tumor of the kidney. It is often found incidentally and in most cases can be managed conservatively. Rupture of the kidney with hemorrhage is a well-known complication that may be serious and life-threatening. Known risk factors for hemorrhage include anticoagulation as well as pregnancy, increased size of the lesion, high lesion vascularity, and aneurysm formation within the tumor. OBJECTIVES: The aim is to raise awareness of potential HCSE-induced anticoagulation, including, as in the case presented, acute renal AML hemorrhage. CASE REPORT: The case of a patient taking HCSE for venous insufficiency is presented. The patient suffered a life-threatening rupture of the kidney in the presence of known renal AML. She underwent emergency embolization with a successful outcome. Because HCSE-containing products are thought to be generally safe in the treatment of chronic venous insufficiency, it is important to be mindful of their potential anticoagulant properties and, therefore, their relative contraindication both in patients taking other anticoagulants and those with known renal AML. CONCLUSION: We demonstrate a potentially life-threatening association between HSCE-containing products and renal AML, highlighting the risk associated with HSCE-induced anticoagulation.

  4. A case of life-threatening obstetrical hemorrhage secondary to placental abruption at 17 weeks of gestation

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    Toshihiko Kinoshita

    2014-03-01

    Full Text Available A 40-year old woman, gravida 4, para 4, presented with sudden lower abdominal pain and severe vaginal bleeding at 17 weeks of gestation. Clinical symptoms and ultrasonographic finding revealed placental abruption. The volume of bleeding was heavy and led to disseminated intravascular coagulation and hypovolemic shock. We performed blood transfusion and therapy to treat the critical condition. However, the mother’s condition continued to worsen. Therefore, we performed a hysterotomy and aborted the pregnancy to save the mother. Since heavy bleeding caused by placental abruption leading to a life-threatening condition for a mother before the 20 weeks of gestation is very rare, the present case is an important case study.

  5. Crouzon’s Syndrome with Life-Threatening Ear Bleed: Ruptured Jugular Vein Diverticulum Treated by Endovascular Embolization

    Energy Technology Data Exchange (ETDEWEB)

    Mondel, Prabath Kumar, E-mail: prabathmondel@gmail.com; Anand, Sunanda, E-mail: sunandaanand@gmail.com; Limaye, Uday S., E-mail: uslkem@gmail.com [Lilavati Hospital and Research Centre, Department of Interventional Neuroradiology (India)

    2015-08-15

    Crouzon’s syndrome is the commonest variety of syndromic craniosynostosis. Life-threatening ear bleed due to ruptured jugular venous diverticulum in Crouzon’s syndrome has not been described previously. In patients with syndromic craniosynostosis, definitive repair of jugular diverticulum by open surgery is fraught with high risk of bleeding, poor functional outcomes, and even death. A 24-year-old woman with Crouzon’s syndrome presented with conductive hearing loss and recurrent episodes of torrential bleeding from her left ear. On computed tomography, a defect in the roof of jugular fossa containing jugular venous diverticulum immediately inferior to the bony external auditory canal was seen. The clinical presentation, imaging features, and endovascular management of Crouzon’s syndrome due to a ruptured jugular venous diverticulum is described.

  6. Life-threatening colonic hemorrhage in Crohn`s disease: angiographic appearance; Angiographische Diagnostik einer lebensbedrohlichen Kolonblutung bei Morbus Crohn

    Energy Technology Data Exchange (ETDEWEB)

    Muhr, T.; Lenglinger, F.X.; Froehler, W.; Meindl, S.; Spoettl, A. [Allgemeines oeffentliches Krankenhaus der Barmherzigen Schwestern vom Heiligen Kreuz, Wels (Austria). Inst. Radiologie I; Allinger, S. [Allgemeines oeffentliches Krankenhaus der Barmherzigen Schwestern vom Heiligen Kreuz, Wels (Austria). Abt. Interne I; Balon, R. [Allgemeines oeffentliches Krankenhaus der Barmherzigen Schwestern vom Heiligen Kreuz, Wels (Austria). Inst. Pathologie I

    1997-09-01

    Life-threatening colonic hemorrhage is a very rare condition in Crohn`s disease. Lower gastroinstestinal hemorrhage in Crohn`s disease occurs in 0.6-2.5% of cases. In a patient presenting with severe gastrointestinal bleeding after ileocolectomy, mesenteric angiography provided precise localisation of the bleeding site in the area of the splenic flexure. (orig.) [Deutsch] Lebensbedrohliche durch einen Morbus Crohn hervorgerufene Blutungen im Dickdarmbereich sind mit einer Inzidenz von 0,6-2,5% eine Raritaet. Wir berichten ueber einen an Morbus Crohn erkrankten Patienten, bei dem nach einer Ileozoekalresektion eine massive Blutung des unteren Gastrointestinaltraktes aufgetreten war. Angiographisch gelang eine exakte Lokalisation der Blutungsquelle im Bereich der linken Kolonflexur. (orig.)

  7. Hypertension and Life-Threatening Bleeding in Children with Relapsed Acute Myeloblastic Leukemia Treated with FLT3 Inhibitors.

    Science.gov (United States)

    Yılmaz Karapınar, Deniz; Karadaş, Nihal; Önder Siviş, Zühal; Balkan, Can; Kavaklı, Kaan; Aydınok, Yeşim

    2015-09-01

    Experiences with new multikinase inhibitors are limited, especially in children. In this report we summarize our experience with 2 patients with relapsed acute myeloblastic leukemia (AML), one with FMS-like tyrosine kinase-3-internal tandem duplication mutation and the other with a single base mutation (D835Y). Both patients received sorafenib, one for 19 days and the other for 42 days, with clofarabine-including chemotherapy. One additionally received sunitinib for a total of 20 days. Both patients developed severe pancytopenia, hypertension, life-threatening bleedings from the gastrointestinal system, and, finally, intrapulmonary hemorrhage. Although both reached severe aplasia of the bone marrow without blastic infiltration, death occurred with neutropenic sepsis. PMID:25912283

  8. Hypertension and Life-Threatening Bleeding in Children with Relapsed Acute Myeloblastic Leukemia Treated with FLT3 Inhibitors

    Directory of Open Access Journals (Sweden)

    Deniz Yılmaz Karapınar

    2015-09-01

    Full Text Available Experiences with new multikinase inhibitors are limited, especially in children. In this report we summarize our experience with 2 patients with relapsed acute myeloblastic leukemia (AML, one with FMS-like tyrosine kinase-3-internal tandem duplication mutation and the other with a single base mutation (D835Y. Both patients received sorafenib, one for 19 days and the other for 42 days, with clofarabine-including chemotherapy. One additionally received sunitinib for a total of 20 days. Both patients developed severe pancytopenia, hypertension, life-threatening bleedings from the gastrointestinal system, and, finally, intrapulmonary hemorrhage. Although both reached severe aplasia of the bone marrow without blastic infiltration, death occurred with neutropenic sepsis.

  9. Mind's response to the body's betrayal: Gestalt/Existential therapy for clients with chronic or life-threatening illnesses.

    Science.gov (United States)

    Imes, Suzanne A; Clance, Pauline Rose; Gailis, Andra T; Atkeson, Ellen

    2002-11-01

    In the literature on chronic or life-threatening illness, there is an overriding emphasis on clients' psychological coping styles and how they relate to psychological functioning. By contrast, in our approach, we look at the subjective mind/body experiences that clients have of their illness and how their lives are impacted by their illness. As psychotherapists, we address their existential distress, pain, body experience, thoughts, and feelings, as well as their efforts to cope or find meaning in their illness. We summarize Gestalt/Existential therapy for chronic illness, illustrate the approach with three case-vignettes, and stress the importance of attending to each client's unique responses to illness. PMID:12412147

  10. Life-threatening hypersplenism due to idiopathic portal hypertension in early childhood: case report and review of the literature

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    Duck Christina

    2010-10-01

    Full Text Available Abstract Background Idiopathic portal hypertension (IPH is a disorder of unknown etiology and is characterized clinically by portal hypertension, splenomegaly, and hypersplenism accompanied by pancytopenia. This study evaluates the pathogenic concept of the disease by a systematic review of the literature and illustrates novel pathologic and laboratory findings. Case Presentation We report the first case of uncontrolled splenic hyperperfusion and enlargement with subsequent hypersplenism leading to life-threatening complications of IPH in infancy and emergent splenectomy. Conclusions Our results suggest that splenic NO and VCAM-1, rather than ET-1, have a significant impact on the development of IPH, even at a very early stage of disease. The success of surgical interventions targeting the splenic hyperperfusion suggests that the primary defect in the regulation of splenic blood flow seems to be crucial for the development of IPH. Thus, beside other treatment options splenectomy needs to be considered as a prime therapeutic option for IPH.

  11. Life-Threatening Contraceptive-Related Pulmonary Embolism in a 14-Year-Old Girl with Hereditary Thrombophilia

    DEFF Research Database (Denmark)

    Hellfritzsch, Maja; Grove, Erik Lerkevang

    2015-01-01

    BACKGROUND: The prothrombotic effect of combined oral contraceptives (COCs) is well-established, with a 3-6-fold increased risk of VTE compared to non-users. When initiation of COCs is considered, it is therefore of paramount importance to carefully evaluate all other potential risk factors for VTE....... Based on a case of life-threatening COC-associated pulmonary embolism in a girl heterozygous for the prothrombin G20210A mutation and with a family history of thrombotic disease, we discuss the importance of assessing not just the genotype but also the phenotype when considering initiation of COCs in...... total occlusion of the right pulmonary artery, and several minor peripheral embolisms bilaterally. She was successfully treated with thrombolysis (alteplase) followed by aPTT-adjusted heparin infusion until adequate anticoagulation with warfarin was achieved. Two years earlier, the patient had been...

  12. Life-threatening arrhythmia verification in ICU patients using the joint cardiovascular dynamical model and a Bayesian filter.

    Science.gov (United States)

    Sayadi, Omid; Shamsollahi, Mohammad B

    2011-10-01

    In this paper, a novel nonlinear joint dynamical model is presented, which is based on a set of coupled ordinary differential equations of motion and a Gaussian mixture model representation of pulsatile cardiovascular (CV) signals. In the proposed framework, the joint interdependences of CV signals are incorporated by assuming a unique angular frequency that controls the limit cycle of the heart rate. Moreover, the time consequence of CV signals is controlled by the same phase parameter that results in the space dimensionality reduction. These joint equations together with linear assignments to observation are further used in the Kalman filter structure for estimation and tracking. Moreover, we propose a measure of signal fidelity by monitoring the covariance matrix of the innovation signals throughout the filtering procedure. Five categories of life-threatening arrhythmias were verified by simultaneously tracking the signal fidelity and the polar representation of the CV signal estimations. We analyzed data from Physiobank multiparameter databases (MIMIC I and II). Performance evaluation results demonstrated that the sensitivity of the detection ranges over 93.50% and 100.00%. In particular, the addition of more CV signals improved the positive predictivity of the proposed method to 99.27% for the total arrhythmic types. The method was also used for false arrhythmia suppression issued by ICU monitors, with an overall false suppression rate reduced from 42.3% to 9.9%. In addition, false critical ECG arrhythmia alarm rates were found to be, on average, 42.3%, with individual rates varying between 16.7% and 86.5%. The results illustrate that the method can contribute to, and enhance the performance of clinical life-threatening arrhythmia detection. PMID:21324772

  13. Sodium hypochlorite accident resulting in life-threatening airway obstruction during root canal treatment: a case report

    Directory of Open Access Journals (Sweden)

    Al-Sebaei MO

    2015-03-01

    Full Text Available Maisa O Al-Sebaei,1 Omar A Halabi,2 Ibrahim E El-Hakim3 1Department of Oral and Maxillofacial Surgery, King Abdulaziz University – Faculty of Dentistry, Jeddah, Kingdom of Saudi Arabia; 2Saudi Board of Oral and Maxillofacial Surgery, Al-Noor Specialist Hospital, Makkah, Kingdom of Saudi Arabia; 3Department of Oral and Maxillofacial Surgery, Riyadh Colleges of Dentistry and Pharmacy, Riyadh, Kingdom of Saudi Arabia Aim: This case report describes a serious and life-threatening complication of the use of sodium hypochlorite as an irrigation solution in root canal therapy. Summary: This case report describes a hypochlorite accident that occurred in a healthy 42-year-old female who was undergoing routine root canal therapy for the lower right central incisor (tooth #41. After approximately 1 hour of irrigation with 3% sodium hypochlorite (for a total of 12 cc, the patient complained of severe pain and burning in the lip. The swelling progressed over the next 8 hours to involve the sublingual and submental fascial spaces with elevation of the tongue and resultant upper airway obstruction. The patient was intubated and remained on mechanical ventilation for 3 days. She recovered without any skin necrosis or nerve deficits. Key learning points: This case report highlights the importance of carefully performing root canal irrigation with sodium hypochlorite to avoid complications. Careful injection without pressure, the use of proper rubber dam isolation, and the use of the endodontic needle are necessary to avoid this type of complication. Although it is a safe root canal irrigation solution, its use may lead to life-threatening complications. Early recognition and management of the untoward effects of sodium hypochlorite are vital for the patient's safety. Keywords: complications of root canal, facial edema, root canal irrigation, root canal therapy, sodium hypochlorite, upper airway obstruction

  14. Acquired hemophilia as the cause of life-threatening hemorrhage in a 94-year-old man: a case report

    Directory of Open Access Journals (Sweden)

    Blanchard Elizabeth

    2010-07-01

    Full Text Available Abstract Introduction Acquired factor VIII deficiency is a rare entity that can lead to severe and life-threatening bleeding. We describe a case of severe bleeding from the tongue secondary to acquired hemophilia and discuss treatment options, including aminocaproic acid and recombinant factor VIII, which have not been widely reported in the literature for the management of such patients. Case presentation A 94-year-old Caucasian man presented to our institution with diffuse bruising and extensive bleeding from the tongue secondary to mechanical trauma. He had no prior history of bleeding and his medical history was unremarkable except for dementia and hypertension. Coagulation studies revealed a prolonged activated partial thromboplastin time and a mixing study was consistent with the presence of an inhibitor. Quantitative assays revealed a reduced level of factor VIII activity (1% and the presence of a factor VIII inhibitor, measured at seven Bethesda units, in the serum. Oral prednisone therapy (60mg/day was given. He also received intravenous aminocaproic acid and human concentrate of factor VIII (Humate-P and topical anti-thrombolytic agents (100 units of topical thrombin cream. His hospital course was prolonged because of persistent bleeding and the development of profuse melena. He required eight units of packed red blood cells for transfusion. Hospitalization was also complicated by bradycardia of unclear etiology, which started after infusion of aminocaproic acid. His activated partial thromboplastin time gradually normalized. He was discharged to a rehabilitation facility three weeks later with improving symptoms, stable hematocrit and resolving bruises. Conclusions Clinicians should suspect a diagnosis of acquired hemophilia in older patients with unexplained persistent and profound bleeding from uncommon soft tissues, including the tongue. Use of factor VIII (Humate-P and aminocaproic acid can be useful in this coagulopathy but

  15. [Life threatening salicylate poisoning caused by percutaneous absorption in severe ichthyosis vulgaris].

    Science.gov (United States)

    Germann, R; Schindera, I; Kuch, M; Seitz, U; Altmeyer, S; Schindera, F

    1996-08-01

    In a 7-year-old boy, ichthyosis vulgaris was treated with a 10% ointment for application over a large area of the body surface. In this way, the child received 400 g salicylic acid (0.6 g/kg body weight per day) percutaneously over a period of 4 weeks. The patient was referred to hospital by the family doctor: he was in a deep somnolent state, apparently caused by hyperventilation following wheezing, vomiting, tinnitus and vertigo. Salicylate intoxication was suspected because of metabolic acidosis, an anion gap and respiratory overcompensation. The diagnosis was confirmed by a serum salicylate level of 985 micrograms/ml (therapeutic level 150-300 micrograms/ml). Following forced diuresis and alkalization with sodium bicarbonate, haemodialysis was unnecessary. As the salicylate level declined to values within the therapeutic range, the patient started to recover consciousness, waking on the 4th day. By day 6 there were still obvious neurological deficiencies. Fecal incontinence, bilateral ptosis and intermittent diverging strabismus on the right persisted for some weeks. It was 6 months before complete neurological resolution was achieved. The pathogenesis of salicylate toxicity and the need for safer therapies for ichthyosis vulgaris are discussed.

  16. Focused sonography of the heart, lungs, and deep veins identifies missed life-threatening conditions in admitted patients with acute respiratory symptoms

    DEFF Research Database (Denmark)

    Laursen, Christian B; Sloth, Erik; Lambrechtsen, Jess;

    2013-01-01

    Patients with acute respiratory symptoms still remain a diagnostic challenge. The aim of the study was to evaluate whether focused sonography could potentially diagnose life-threatening conditions missed at the primary assessment in a patient population consisting of admitted patients with acute ...

  17. The Importance of Awareness and Communication for the Inclusion of Young People with Life-Limiting and Life-Threatening Conditions in Mainstream Schools and Colleges

    Science.gov (United States)

    Asprey, Anthea; Nash, Tricia

    2006-01-01

    Anthea Asprey and Tricia Nash both belong to the Children's Hospice South West Research Group, based at the University of Exeter. In this article, they report one aspect of a research project designed to determine the adequacy of support for young people with life-limiting and life-threatening conditions in the education system. They describe here…

  18. Life-threatening allergic vasculitis after clipping an unruptured aneurysm: Case report, weighing the risk of nickel allergy

    Directory of Open Access Journals (Sweden)

    Andrew Grande

    2014-01-01

    Full Text Available Background: This case report represents one of the estimated 17,000 aneurysms clipped annually in the United States, often with nickel-containing clips. The authors highlight the development of life-threatening allergic vasculitis in a 33-year-old woman after aneurysm clipping. Case Description: After suffering subarachnoid hemorrhage, the patient had coil embolization at another facility for rupture of a right internal carotid artery (ICA aneurysm. An incidental finding, an unruptured left posterior communicating artery aneurysm unamenable to coiling, was then successfully clipped via a left pterional craniotomy. Arriving in our emergency department 11 days later, she progressively declined during the next weeks, facing deteriorating clinical status (i.e. seizures and additional infarctions in the left frontal lobe, midline shift, and new infarctions in the bilateral frontal lobe, right sylvian, right insular regions, and posterior cerebral artery distribution. During decompressive surgery, biopsy findings raised the possibility of lymphocytic vasculitis; consultations with rheumatology, allergy, and immunology specialists identified that our patient had a nickel allergy. After reoperation to replace the nickel-containing clip with one of a titanium alloy, the patient had an uncomplicated postoperative course and was discharged 6 days later to a rehabilitation facility. Conclusions: Nickel-related allergies are more common than appreciated, affecting up to 10% of patients. Fortunately, severe reactions are rare; nevertheless, vascular neurosurgeons should be aware of this potential complication when using cobalt alloy aneurysms clips. The use of titanium alloy clips eliminates this risk.

  19. Awareness about a Life-Threatening Condition: Ectopic Pregnancy in a Network for Surveillance of Severe Maternal Morbidity in Brazil

    Directory of Open Access Journals (Sweden)

    Edilberto Alves Rocha Filho

    2014-01-01

    Full Text Available Objective. To assess occurrence of severe maternal complications associated with ectopic pregnancy (EP. Method. A multicenter cross-sectional study was conducted, with prospective surveillance of potentially life-threatening conditions (PLTC, maternal near miss (MNM, and maternal death (MD. EP complications, patient sociodemographic/obstetric characteristics, and conditions of severity management were assessed, estimating prevalence ratios with respective 95% CI. Factors independently associated with greater severity were identified using multiple regression analysis. Results. Of the 9.555 severe maternal morbidity patients, 312 women (3.3% had complications after EP: 286 (91.7% PLTC, 25 (8.0% MNM, and 1 (0.3% MD. Severe maternal outcome ratio (SMOR was 0.3/1000 LB among EP cases and 10.8/1000 LB among other causes. Complicated EP patients faced a higher risk of blood transfusion, laparotomy, and lower risk of ICU admission and prolonged hospitalization than women developing complications resulting from other causes. Substandard care was the most common in more severe maternal morbidity and EP cases (22.7% MNM and MD versus 15% PLTC, although not significant. Conclusion. Increased maternal morbidity due to EP raised awareness about the condition and its impact on female reproductive life. No important risk factors for greater severity were identified. Care providers should develop specific guidelines and interventions to prevent severe maternal morbidity.

  20. Efficacy of selective arterial embolisation for the treatment of life-threatening post-partum haemorrhage in a large population.

    Directory of Open Access Journals (Sweden)

    Cyril Touboul

    Full Text Available BACKGROUND: The objective of this study was to assess efficacy and determine the optimal indication of selective arterial embolisation (SAE in patients with life-threatening post-partum haemorrhage (PPH. METHODOLOGY/PRINCIPAL FINDINGS: One hundred and two patients with PPH underwent SAE and were included from January 1998 to January 2002 in our university care center. Embolisation was considered effective when no other surgical procedure was required. Univariate and multivariate statistical analysis were performed. SAE was effective for 73 patients (71.5%, while 29 required surgical procedures. SAE was effective in 88.6% of women with uterine atony that was associated with positive outcome (OR 4.13, 1.35-12.60, whereas caesarean deliveries (OR 0.16, 0.04-0.5 and haemodynamic shock (OR 0.21, 0.07-0.60 were associated with high failure rates, 47.6% and 39.1%, respectively. CONCLUSIONS/SIGNIFICANCE: Success rate for SAE observed in a large population is lower than previously reported. It is most likely to succeed for uterine atony but not recommended in case of haemodynamic shock or after caesarean section.

  1. Laryngomalacia and complicated, life-threatening mTOR-positive Kaposiform hemangioendothelioma cured by Supraglottoplasty and sirolimus.

    Science.gov (United States)

    Schroeder, U; Lauten, M; Stichtenoth, G; Gebhard, M P E; Buchholz, M; Kaiser, M M

    2014-11-01

    The therapy of complicated Kaposiform hemangioendothelioma (KHE) is still difficult. We present the first case of laryngomalacia with simultaneous mammalian target of Rapamycin (mTOR)-positive KHE of the neck and thoracic inlet and concurrent Kasabach-Meritt Phenomenon (KMP) in an 11-month-old boy suffering life-threatening progress despite intravenous vincristine, corticosteroids, propranolol and local interstitial laser-application. The laryngomalacia restored after laser-supraglottoplasty. Successfully treatment of the prior fatal course of the KHE with KMP was initiated not till adding the mTOR inhibitor sirolimus to therapy. After 16 months single therapy of KHE with oral sirolimus the boy presented free of symptoms with minimal residual disease and excellent functional long-term results. Thus we stopped sirolimus therapy. The results are stable for 9 months without therapy. The special features including full report of histopathologic findings of this utmost complicated case are demonstrated in detail underlining the effectiveness of sirolimus for KHE. PMID:24810750

  2. Life-threatening hyperkalaemia developing following excessive ingestion of orange juice in a patient with baseline normal renal function.

    Science.gov (United States)

    Javed, R A; Marrero, K; Rafique, M; Khan, M U; Jamarai, D; Vieira, J

    2007-11-01

    Hyperkalaemia is a less-recognised life-threatening cause of paralysis. We describe a 51-year-old African-American man, who suffered from muscle weakness progressing to ascending symmetric paralysis, and inability to masticate. Physical examination revealed flaccid paralysis with areflexia of the four limbs. Computed tomography of the brain and cervical spine did not demonstrate any organic lesions. Laboratory investigations revealed serum potassium 9.0 mEq/L (not haemolysed), blood urea nitrogen 34 mg/dL, and serum creatinine 2.0 mg/dL. Electrocardiography showed typical features of hyperkalaemia. After emergent treatment for hyperkalaemia was initiated, serum potassium was rapidly-normalised to 5 mEq/L and all neuromuscular symptoms reversed within one hour. Upon reviewing his food and medication history, he admitted drinking 2.5 litres of orange juice (which contains about 450 mg of potassium in 1,000 ml) per day for the past three weeks to quench his thirst. Hyperkalaemia should be borne in mind in the differential diagnosis of acute paralysis. Hidden sources of potassium intake, such as orange juice, should not be overlooked, even in patients with baseline normal renal function. PMID:17975680

  3. Non-invasive tools for the diagnosis of potentially life-threatening gynaecological emergencies: a systematic review.

    Directory of Open Access Journals (Sweden)

    Viola Polena

    Full Text Available To identify non-invasive tools for diagnosis of the major potentially life-threatening gynaecological emergencies (G-PLEs reported in previous studies, and to assess their diagnostic accuracy.MEDLINE; EMBASE; Cochrane Central Register of Controlled Trials (CENTRAL; The Cochrane Library were searched to identify all eligible studies published in English or French between January 1990 and December 2012. Studies were considered eligible if they were primary diagnostic studies of any designs, with a gold standard and with sufficient information for construction of a 2 × 2 contingency table, concerning at least one of the following G-PLEs: complicated ectopic pregnancy, complicated pelvic inflammatory disease, adnexal torsion and haemoperitoneum of any gynaecological origin. Extraction of data and assessment of study quality were conducted by two independent reviewers. We set the thresholds for the diagnostic value of signs retrieved at Sensibility ≥ 95% and LR-≤ 0.25, or Specificity ≥ 90% and LR+ ≥ 4.We identified 8288 reports of diagnostic studies for the selected G-PLEs, 45 of which met the inclusion criteria. The methodological quality of the included studies was generally low. The most common diagnostic tools evaluated were transvaginal ultrasound (20/45, followed by medical history (18/45, clinical examination (15/45 and laboratory tests (14/45. Standardised questioning about symptoms, systolic blood pressure0.85, identification of a mass by abdominal palpation or vaginal examination, haemoglobin concentration <10 g/dl and six ultrasound and Doppler signs presented high performances for the diagnosis of G-PLEs. Transvaginal ultrasound was the diagnostic tool with the best individual performance for the diagnosis of all G-PLEs.This systematic review suggests that blood pressure measurement, haemoglobin tests and transvaginal ultrasound are cornerstone examinations for the diagnosis of G-PLEs that should be available in all

  4. Should a patient with a life threatening illness be informed of the diagnosis? A survey of physicians and medical students in Calicut

    Directory of Open Access Journals (Sweden)

    Purakkal Divya

    2004-01-01

    Full Text Available AIM: To ascertain how doctors and under graduate medical students in a teaching hospital felt about revealing and knowing the diagnosis of a life threatening illness. MATERIALS AND METHODS: 850 respondents (200 pre clinical students, 300 clinical students, 100 interns, 150 postgraduate registrars and 100 faculty were interviewed with the help of a set questionnaire. RESULTS: 70% of pre clinical students, 85% of clinical students and 89% of doctors stated that the diagnosis should be revealed. Women preclinical students, (60%, were significantly less in favour of the diagnosis being revealed than other groups. 81% of pre - clinical students, 89% of clinical students, 94% of postgraduates and 95% of faculty would want to know the diagnosis if they themselves were to develop a life threatening illness.

  5. Traumatic bilateral carotid artery dissection following severe blunt trauma: a case report on the difficulties in diagnosis and therapy of an often overlooked life-threatening injury

    OpenAIRE

    Crönlein, Moritz; Sandmann, Gunther H.; Beirer, Marc; Wunderlich, Silke; Biberthaler, Peter; Huber-Wagner, Stefan

    2015-01-01

    Background Traumatic carotid artery dissections are very rare, often overlooked and life-threatening injuries. Diagnosis and treatment are difficult especially in multiple injured patients. Case presentation We report on a 28-year-old female major trauma patient (injury severity score, ISS 50) who was involved in a motor vehicle accident. She was primarily transferred to a level II trauma center. After initial assessment and operative management, an anisocoria was diagnosed on the intensive c...

  6. Life-threatening ventricular arrhythmia due to silent coronary artery spasm: usefulness of I-123 metaiodobenzylguanidine scintigraphy for detecting coronary artery spasm in the era of automated external defibrillators: a case report

    OpenAIRE

    Kaku, Bunji; Katsuda, Shoji; Taguchi, Tomio

    2015-01-01

    Introduction Cardiac arrhythmia is sometimes life-threatening, and automated external defibrillators are presently used in some countries. Coronary artery spasm is one of the primary causes of life-threatening arrhythmia. In general, chest symptoms are key indicators of possible coronary artery spasm; however, if chest symptoms are not present, clinicians may not suspect this disease. We encountered a patient who had recovered from ventricular fibrillation treated by using an automated extern...

  7. Delayed, life-threatening lower gastrointestinal hemorrhage in an infant after serial transverse enteroplasty: treatment with transcatheter n-butyl-2-cyanoacrylate embolization

    Energy Technology Data Exchange (ETDEWEB)

    Bogue, Conor O.; Alzahrani, Amin I.; John, Philip R.; Amaral, Joao G. [Hospital for Sick Children, Division of Image Guided Therapy, Department of Diagnostic Imaging, Toronto (Canada); Wales, Paul W. [Hospital for Sick Children, Department of Surgery and the Group for Improvement of Intestinal Function and Treatment (GIFT), Toronto (Canada)

    2009-10-15

    We report a case of n-butyl-2-cyanoacrylate glue embolization of life-threatening lower gastrointestinal (LGI) hemorrhage in a 10-month-old boy. The child had a history of gastroschisis and short-bowel syndrome. Six months prior to the LGI bleed, he had undergone a serial transverse enteroplasty (STEP) to lengthen his intestine. To the best of our knowledge this is both the first report of successful glue embolization for LGI bleeding in a child and also the first report of severe hemorrhage after the STEP procedure. (orig.)

  8. Delayed, life-threatening lower gastrointestinal hemorrhage in an infant after serial transverse enteroplasty: treatment with transcatheter n-butyl-2-cyanoacrylate embolization

    International Nuclear Information System (INIS)

    We report a case of n-butyl-2-cyanoacrylate glue embolization of life-threatening lower gastrointestinal (LGI) hemorrhage in a 10-month-old boy. The child had a history of gastroschisis and short-bowel syndrome. Six months prior to the LGI bleed, he had undergone a serial transverse enteroplasty (STEP) to lengthen his intestine. To the best of our knowledge this is both the first report of successful glue embolization for LGI bleeding in a child and also the first report of severe hemorrhage after the STEP procedure. (orig.)

  9. Liraglutide Treatment Is Associated with a Low Frequency and Magnitude of Antibody Formation with No Apparent Impact on Glycemic Response or Increased Frequency of Adverse Events

    DEFF Research Database (Denmark)

    Buse, John B; Garber, Alan; Rosenstock, Julio;

    2011-01-01

    Context: Therapeutic proteins/peptides can produce immunogenic responses that may increase the risk of adverse events or reduce efficacy. Objective: The objectives were to measure and characterize antibody formation to liraglutide, a glucagon-like peptide-1 receptor agonist, to investigate the im...

  10. Typhoid ulcer causing life-threatening bleeding from Dieulafoy's lesion of the ileum in a seven-year-old child: a case report

    Directory of Open Access Journals (Sweden)

    Rashid Abbas

    2010-06-01

    Full Text Available Abstract Introduction We describe a case of rare complication of typhoid fever in a seven-year-old child and review the literature with regard to other rare causes of bleeding per rectum. Dieulafoy's lesion is an uncommon but important cause of recurrent gastrointestinal bleeding. Dieulafoy's lesion located extragastrically is rare. We report a case of typhoid ulcer with Dieulafoy's lesion of the ileum causing severe life-threatening bleeding and discuss the management of this extremely uncommon entity. Case presentation As a complication of typhoid fever, a seven-year-old Kurdish girl from Northern Iraq developed massive fresh bleeding per rectum. During colonoscopy and laparotomy, she was discovered to have multiple bleeding ulcers within the Dieulafoy's lesion in the terminal ileum and ileocecal region. Conclusion Although there is no practical way of predicting the occurrence of such rare complications, we emphasize in this case report the wide array of pathologies that can result from typhoid fever.

  11. Perspectives of Simplified Graphical Domain-Specific Languages as Communication Tools in Developing Mobile Systems for Reporting Life-Threatening Situations

    Directory of Open Access Journals (Sweden)

    Żyła Kamil

    2015-12-01

    Full Text Available Reporting systems, based on mobile technologies and feedback from regular citizens, are constantly gaining popularity, especially when it comes to environmental and cultural heritage protection. Reporting life-threatening situations, such as sudden natural disasters or traffic accidents, constitutes the same class of problems and could be aided by IT systems of similar architecture. Emergency services also could benefit from such kinds of solutions, e.g., by getting an accurate location of the place where help is needed as well as fast exchange of information. Designing and developing systems for reporting life-threatening situations is not a trivial task, requiring tight cooperation among software developers and experts of different domains, who most likely would have trouble with industrially recognized languages and notations. Thus, the question is whether using simplified graphical domain-specific languages (SGDSLs could help in creating a common communication platform. In order to answer that question, short workshops were conducted at the University of Economics in Prague, Czech Republic and in Lublin, Poland. They involved people trained during their studies to work in administration and emergency services, among others, as policy makers, medicine specialists, environmentalists, or managers. All participants received brief training in graphical modeling languages in the context of modeling mobile applications and were asked to voluntarily fill in an anonymous survey in order to check their knowledge about and attitude toward the presented technologies. Most respondents claimed that SGDSLs oriented on defining a flow of actions might be valuable as tools for creating a common communication platform.

  12. Life-Threatening Contraceptive-Related Pulmonary Embolism in a 14-Year-Old Girl with Hereditary Thrombophilia

    OpenAIRE

    Hellfritzsch, Maja; Grove, Erik Lerkevang

    2015-01-01

    Patient: Female, 14 Final Diagnosis: Pulmonary embolism Symptoms: Chest pain • dyspnea • syncope Medication: Combined oral contraceptives Clinical Procedure: — Specialty: Internal Medicine Objective: Adverse events of drug therapy Background: The prothrombotic effect of combined oral contraceptives (COCs) is well-established, with a 3–6-fold increased risk of VTE compared to non-users. When initiation of COCs is considered, it is therefore of paramount importance to carefully evaluate all oth...

  13. Recognizing Life-threatening Features of Dengue in Children and Health Seeking Behavior in Dengue Emergency Amongst Parents and Carers: A Cross-sectional study in Gombak District, Malaysia.

    Science.gov (United States)

    Ariffin, F; Ramli, A S; Naim, N; Selamat, M I; Syed-Jamal, S J

    2014-10-01

    Dengue is life-threatening and the paediatric population is highly susceptible to complications. Deterioration can occur rapidly and ability to recognise early warning signs is crucial. This study aims to determine the knowledge and awareness of parents and carers and to predict their ability in recognising life-threatening symptoms and signs of dengue in children and to assess their health-seeking behaviour in dengue emergency. Methods This is a crosssectional study involving parents and carers of children ≤ 12 years old in schools and kindergartens in the Gombak district. Demographic details, knowledge on life-threatening symptoms and signs of dengue and health-seeking behaviour were collected using a self-administered questionnaire and knowledge scoring was done. The questionnaire was pilot tested with a Cronbach alpha of 0.82. The results were analysed using SPSS version 20.0. Results Total respondents were 866 with 44.8% men and 55.2% women. The mean age was 40.3 years (SD ± 5.7). Knowledge score of dengue life threatening features among respondents were good (30.0%) to average (56.8%). Respondents were able to recognise fever (98.5%), petechial rash (97.1%) and bleeding (65.2%) but were less able to recognise abdominal pain (22.3%) and passing less urine (28.2%) as life threatening dengue features. However, the ability to recognise fever is a poor predictor in recognising life threatening dengue in children compared to all other symptoms which were good predictors. A respondent that recognise stomach pain or neck stiffness were five times more likely to recognise life-threatening dengue. Respondents preferred to bring their children to the clinic (50.8%) or hospital (37.8%) themselves Instead of calling for ambulance. Worryingly, some would give antipyretics (3.6%) or wait for improvements (7.8%). Conclusion Concerted efforts by the schools, healthcare professionals and health authorities are required to educate parents and carers to identify life-threatening

  14. Treatment of life-threatening wounds with a combination of allogenic platelet-rich plasma, fibrin glue and collagen matrix, and a literature review.

    Science.gov (United States)

    Asadi, Mehdi; Alamdari, Daryoush Hamidi; Rahimi, Hamid Reza; Aliakbarian, Mohsen; Jangjoo, Ali; Abdollahi, Abbas; Bahar, Mostafa Mehrabi; Azadmand, Ali; Forghani, Naser; Sadegh, Mohammad Nori; Khayamy, Mohammad Esmail; Seifalian, Alexander

    2014-08-01

    Currently there is no ideal procedure for the treatment of recalcitrant ulcers that are unresponsive to the majority of common treatments. However, several novel approaches have been proposed, including bone marrow stem cells, platelets, fibrin glue and collagen matrix. For the first approach treatment of a chronic wound, a non-invasive method is highly desirable. The present study was undertaken with the aim of evaluating the effect of a combination of platelets, fibrin glue and collagen matrix (PFC) in one treatment. A total of ten patients with aggressive, refractory, life-threatening wounds were recruited for the study and their treatment effects were evaluated. Initially, the ulcers were extensively debrided, measured and photographed at weekly intervals. The PFC combination was applied topically to the wound every two days. Following treatment, the wound was completely closed in nine patients and was markedly reduced in the other patient. The mean 100% healing time for the nine patients was 11.3±5.22 weeks. There was no evidence of local or systemic complications or any abnormal tissue formation, keloid or hypertrophic scarring. Therefore, the results of the present study indicate that in the first approach, the combination of PFC components may be used safely in order to synergize the effect of chronic wound healing.

  15. A Review of and Recommendations for the Management of Patients With Life-Threatening Dabigatran-Associated Hemorrhage: A Single-Center University Hospital Experience.

    Science.gov (United States)

    Kumar, Rohit; Smith, Roy E; Henry, Brian L

    2015-12-01

    Dabigatran is an oral direct thrombin inhibitor that is approved for the prevention of stroke and systemic embolism in nonvalvular atrial fibrillation. Dabigatran has several advantages over warfarin including predictable pharmacokinetics and pharmacodynamics which eliminates the need for routine laboratory monitoring, superiority over warfarin in preventing stroke, or systemic embolism without having an increased risk of bleeding. However, as with any anticoagulant, there remains a real chance of bleeding, including major or life-threatening hemorrhage. Many physicians feel comfortable managing bleeding complications on older anticoagulants like warfarin and heparin, due to extensive experience with the medications along with antidotes to reverse their effects as well as established protocols for treating anticoagulant-associated hemorrhage. However, most physicians have limited clinical experience with dabigatran, there is no specific antidote for dabigatran reversal and there is a paucity of protocols, guidelines, and recommendations for how to manage dabigatran-associated hemorrhage. In this review, we present a case series of patients admitted to our institution for management of bleeding while receiving dabigatran. We retrospectively reviewed these cases to evaluate the efficacy and rationale of the various anticoagulation reversal strategies employed in the context of the existing evidence found in the literature. Specific focus is placed on the therapies utilized and the coagulation studies used to manage these patients. PMID:24668159

  16. Impact of sympathetic innervation on recurrent life-threatening arrhythmias in the follow-up of patients with idiopathic ventricular fibrillation

    Energy Technology Data Exchange (ETDEWEB)

    Paul, Matthias; Acil, Tayfun; Breithardt, Guenter; Wichter, Thomas [Hospital of the University of Muenster, Department of Cardiology and Angiology, Muenster (Germany); Schaefers, Michael; Kies, Peter; Schaefers, Klaus; Schober, Otmar [Hospital of the University of Muenster, Department of Nuclear Medicine, Muenster (Germany)

    2006-08-15

    Idiopathic ventricular fibrillation (IVF) is defined as VF in the absence of any identifiable structural or functional cardiac disease. The underlying pathophysiological mechanisms are unknown. This study was performed to investigate the potential impact of sympathetic dysfunction, assessed by {sup 123}I-meta-iodo-benzylguanidine scintigraphy ({sup 123}I-MIBG SPECT), on the long-term prognosis of patients with IVF. {sup 123}I-MIBG SPECT was performed in 20 patients (mean age 37{+-}13 years) with IVF. Mean follow-up of patients after study entry was 7.2{+-}1.5 years (range 4.9-10.5 years). Ten patients (five men, five women; mean age 43{+-}12 years; p=NS versus study group) with medullary carcinoma of the thyroid gland served as an age-matched control group. Abnormal {sup 123}I-MIBG uptake was observed in 13 patients (65%). During follow-up, 18 episodes of VF/fast polymorphic ventricular tachycardias occurred in four IVF patients with abnormal {sup 123}I-MIBG uptake whereas only two episodes of monomorphic ventricular tachycardia (and no VF) occurred in a single IVF patient with normal {sup 123}I-MIBG uptake. Impairment of sympathetic innervation may indicate a higher risk of future recurrent episodes of life-threatening ventricular tachyarrhythmias in patients with IVF. Studies in larger cohorts are required to validate the significance of {sup 123}I-MIBG SPECT during the long-term follow-up of these patients. (orig.)

  17. A Review of and Recommendations for the Management of Patients With Life-Threatening Dabigatran-Associated Hemorrhage: A Single-Center University Hospital Experience.

    Science.gov (United States)

    Kumar, Rohit; Smith, Roy E; Henry, Brian L

    2015-12-01

    Dabigatran is an oral direct thrombin inhibitor that is approved for the prevention of stroke and systemic embolism in nonvalvular atrial fibrillation. Dabigatran has several advantages over warfarin including predictable pharmacokinetics and pharmacodynamics which eliminates the need for routine laboratory monitoring, superiority over warfarin in preventing stroke, or systemic embolism without having an increased risk of bleeding. However, as with any anticoagulant, there remains a real chance of bleeding, including major or life-threatening hemorrhage. Many physicians feel comfortable managing bleeding complications on older anticoagulants like warfarin and heparin, due to extensive experience with the medications along with antidotes to reverse their effects as well as established protocols for treating anticoagulant-associated hemorrhage. However, most physicians have limited clinical experience with dabigatran, there is no specific antidote for dabigatran reversal and there is a paucity of protocols, guidelines, and recommendations for how to manage dabigatran-associated hemorrhage. In this review, we present a case series of patients admitted to our institution for management of bleeding while receiving dabigatran. We retrospectively reviewed these cases to evaluate the efficacy and rationale of the various anticoagulation reversal strategies employed in the context of the existing evidence found in the literature. Specific focus is placed on the therapies utilized and the coagulation studies used to manage these patients.

  18. Apparent Clustering and Apparent Background Earthquakes Biased by Undetected Seismicity

    CERN Document Server

    Sornette, D

    2005-01-01

    In models of triggered seismicity and in their inversion with empirical data, the detection threshold m_d is commonly equated to the magnitude m_0 of the smallest triggering earthquake. This unjustified assumption neglects the possibility of shocks below the detection threshold triggering observable events. We introduce a formalism that distinguishes between the detection threshold m_d and the minimum triggering earthquake m_0 < m_d. By considering the branching structure of one complete cascade of triggered events, we derive the apparent branching ratio n_a (which is the apparent fraction of aftershocks in a given catalog) and the apparent background source S_a that are observed when only the structure above the detection threshold m_d is known due to the presence of smaller undetected events that are capable of triggering larger events. If earthquake triggering is controlled in large part by the smallest magnitudes as several recent analyses have shown, this implies that previous estimates of the cluster...

  19. Events

    Directory of Open Access Journals (Sweden)

    Igor V. Karyakin

    2016-02-01

    Full Text Available The 9th ARRCN Symposium 2015 was held during 21st–25th October 2015 at the Novotel Hotel, Chumphon, Thailand, one of the most favored travel destinations in Asia. The 10th ARRCN Symposium 2017 will be held during October 2017 in the Davao, Philippines. International Symposium on the Montagu's Harrier (Circus pygargus «The Montagu's Harrier in Europe. Status. Threats. Protection», organized by the environmental organization «Landesbund für Vogelschutz in Bayern e.V.» (LBV was held on November 20-22, 2015 in Germany. The location of this event was the city of Wurzburg in Bavaria.

  20. 危及生命的重症颈部外伤的诊治体会%The management of life-threatening neck trauma

    Institute of Scientific and Technical Information of China (English)

    吴静; 刘业海; 吴开乐; 赵益; 童步升; 高潮兵; 李亦凡; 王杨

    2014-01-01

    目的:探讨危及生命的重症颈部外伤有效的诊治方法。方法回顾性分析我科2005年1月~2010年1月间收住入院的各种颈部外伤病例资料,对危及生命的重症颈部外伤的18例诊治过程及预后情况进行回顾性分析。此类病例,首先根据具体病情进行急救,再根据颈部外伤的具体情况进行不同的处理,急救方法主要包括紧急止血、抗休克治疗、气管切开术、重要脏器合并伤的处理。结果18例颈部外伤中入院前伴有出血性休克症状者7例,同时伴有出血性休克症状和喉梗阻者或开放性喉气管贯通损伤者6例,伴有喉梗阻者3例,伴有气胸或血气胸者2例。本组病例皆急救成功,其中9例行气管切开术,随诊6个月~5年,3例拔管困难,其中1例气管套管上方肉芽组织增生,肉芽切除术后2周拔管;1例胸段气管轻度狭窄,随访半年无堵管后无呼吸困难后予以拔管;1例声门下狭窄,保留气管套管。2例声音嘶哑好转不明显,其中1例喉返神经损伤行修复后声带运动部分恢复,1例因杓区损伤未完全康复。所有患者均无气管食管瘘、咽瘘。结论迅速而准确判断颈部外伤的临床特点,及时采取不同的急救措施和具体有效的颈部探查修复术是治疗重症颈部外伤、防止术后并发症的安全有效方法。%Objective To investigate the effective management of life-threatening neck trauma. Methods We retrospectively analyzed on 18 cases of life-threatening neck trauma inpatients of our hospital from 2005 to 2010. To severe cases, took first-aid firstly according to the specific condition, then adopted approriate treatments to individual condition. Emergency methods mainly include these aspects, firstly, treating for shock to patients who accompanied by shock symptoms. Secondly, stopping bleeding to massive active bleeding. At the same time ,the airway must be secured immediately

  1. Remembering apparent behavior

    DEFF Research Database (Denmark)

    Wagoner, Brady

    2011-01-01

    The present experiment systematically investigates the role of narrative templates (Wertsch, 2002) in remembering. To stimulate the construction of a diversity of narratives I used Heider and Simmel’s (1944) celebrated “apparent behavior” film, in which geometric shapes moving around a screen are...

  2. Apparent Superluminal Behavior

    CERN Document Server

    Jackson, A D; Lautrup, B

    2000-01-01

    The apparent superluminal propagation of electromagnetic signals seen in recent experiments is shown to be the result of simple and robust properties of relativistic field equations. Although the wave front of a signal passing through a classically forbidden region can never move faster than light, an attenuated replica of the signal is reproduced ``instantaneously'' on the other side of the barrier. The reconstructed signal, causally connected to the forerunner rather than the bulk of the input signal, appears to move through the barrier faster than light.

  3. Severe cytomegalovirus infection in apparently immunocompetent patients: a systematic review

    Directory of Open Access Journals (Sweden)

    Varbobitis Ioannis C

    2008-03-01

    Full Text Available Abstract Background The morbidity and mortality associated with cytomegalovirus (CMV infection in immunocompromised patients (especially in HIV-infected patients and transplant recipients, as well as with congenital CMV infection are well known. In contrast, relatively little attention has been paid to the morbidity and mortality that CMV infection may cause in immunocompetent patients. Methods We reviewed the evidence associated with severe manifestations of CMV infection in apparently immunocompetent patients and the potential role of antiviral treatment for these infections. We searched in PubMed, Scopus, and the Cochrane Library for the period of 1950–2007 to identify relevant articles. Results We retrieved 89 articles reporting on severe CMV infection in 290 immunocompetent adults. Among these reports, the gastrointestinal tract (colitis and the central nervous system (meningitis, encephalitis, transverse myelitis were the most frequent sites of severe CMV infection. Manifestations from other organ-systems included haematological disorders (haemolytic anaemia, thrombocytopenia, thrombosis of the venous or arterial vascular system, ocular involvement (uveitis, and lung disease (pneumonitis. The clinical practice reported in the literature has been to prescribe antiviral treatment for the most severe manifestations of monophasic meningoencephalitis (seizures and coma, ocular involvement, and lung involvement due to CMV. Conclusion Severe life-threatening complications of CMV infection in immunocompetent patients may not be as rare as previously thought.

  4. The apparent Universe

    Science.gov (United States)

    Binétruy, P.; Helou, A.

    2015-10-01

    We exploit the parallel between dynamical black holes and cosmological spacetimes to describe the evolution of Friedmann-Lemaître-Robertson-Walker universes from the point of view of an observer in terms of the dynamics of the apparent horizon. Using the Hayward-Kodama formalism of dynamical black holes, we clarify the role of the Clausius relation to derive the Friedmann equations for a Universe, in the spirit of Jacobson’s work on the thermodynamics of spacetime. We also show how dynamics at the horizon naturally leads to the quantum-mechanical process of Hawking radiation. We comment on the connection of this work with recent ideas to consider our observable Universe as a Bose-Einstein condensate and on the corresponding role of vacuum energy.

  5. Rationale for a long-term evaluation of the consequences of potentially life-threatening maternal conditions and maternal "near-miss" incidents using a multidimensional approach.

    Science.gov (United States)

    Pacagnella, Rodolfo C; Cecatti, Jose G; Camargo, Rodrigo P; Silveira, Carla; Zanardi, Dulce T; Souza, Joao P; Parpinelli, Mary A; Haddad, Samira M

    2010-08-01

    Recent advances in health care mean that women survive severe conditions and events related to pregnancy that would previously have resulted in death. Therefore, a greater number of women will experience significant maternal morbidity with significant consequences. Little is known, however, about these long-term consequences. Some investigators have evaluated the repercussions of severe biological or traumatic events, and have reported that survivors are at an increased risk of death in the five years after the event. In addition, they continue to experience both organic and emotional problems such as clinical, cardiac, respiratory, and neurological complications, as well as anxiety and depression, following discharge from hospital. Following a maternal "near-miss" incident, various life domains may be affected (organic, mental, cognitive, and social function), and these must be evaluated in addition to the related economic issues and quality of life. However, because of the diversity of methods and instruments used to evaluate possible repercussions, comparisons between the few studies available on the subject are difficult. An in-depth debate should be initiated to discuss the methodological aspects of such investigation. We propose a conceptual and methodological discussion on the long-term repercussions of severe maternal morbidity based on the evaluation of the following variables: reproductive health, quality of life, posttraumatic stress syndrome, sexual function, postpartum depression, daily functioning, and the physical, neurological, and psychomotor development of the children born after a complicated pregnancy. PMID:21050503

  6. Use of the non-pneumatic anti-shock garment (NASG for life-threatening obstetric hemorrhage: a cost-effectiveness analysis in Egypt and Nigeria.

    Directory of Open Access Journals (Sweden)

    Tori Sutherland

    Full Text Available OBJECTIVE: To assess the cost-effectiveness of a non-pneumatic anti-shock garment (NASG for obstetric hemorrhage in tertiary hospitals in Egypt and Nigeria. METHODS: We combined published data from pre-intervention/NASG-intervention clinical trials with costs from study sites. For each country, we used observed proportions of initial shock level (mild: mean arterial pressure [MAP] >60 mmHg; severe: MAP ≤60 mmHg to define a standard population of 1,000 women presenting in shock. We examined three intervention scenarios: no women in shock receive the NASG, only women in severe shock receive the NASG, and all women in shock receive the NASG. Clinical data included frequencies of adverse health outcomes (mortality, severe morbidity, severe anemia, and interventions to manage bleeding (uterotonics, blood transfusions, hysterectomies. Costs (in 2010 international dollars included the NASG, training, and clinical interventions. We compared costs and disability-adjusted life years (DALYs across the intervention scenarios. RESULTS: For 1000 women presenting in shock, providing the NASG to those in severe shock results in decreased mortality and morbidity, which averts 357 DALYs in Egypt and 2,063 DALYs in Nigeria. Differences in use of interventions result in net savings of $9,489 in Egypt (primarily due to reduced transfusions and net costs of $6,460 in Nigeria, with a cost per DALY averted of $3.13. Results of providing the NASG for women in mild shock has smaller and uncertain effects due to few clinical events in this data set. CONCLUSION: Using the NASG for women in severe shock resulted in markedly improved health outcomes (2-2.9 DALYs averted per woman, primarily due to reduced mortality, with net savings or extremely low cost per DALY averted. This suggests that in resource-limited settings, the NASG is a very cost-effective intervention for women in severe hypovolemic shock. The effects of the NASG for mild shock are less certain.

  7. Loperamide Induced Life Threatening Ventricular Arrhythmia

    Science.gov (United States)

    Bodar, Vijaykumar; Singh, Sharanjit; Frumkin, William; Mangla, Aditya; Doshi, Kaushik

    2016-01-01

    Loperamide is over-the-counter antidiarrheal agent acting on peripherally located μ opioid receptors. It is gaining popularity among drug abusers as opioid substitute. We report a case of a 46-year-old male that was presented after cardiac arrest. After ruling out ischemia, cardiomyopathy, pulmonary embolism, central nervous system pathology, sepsis, and other drug toxicity, we found out that patient was using around 100 mg of Loperamide to control his chronic diarrhea presumably because of irritable bowel syndrome for last five years and consumed up to 200 mg of Loperamide daily for last two days before the cardiac arrest. We hypothesize that the patient's QTc prolongation and subsequent cardiac arrest are due to Loperamide toxicity. Patient experienced gradual resolution of tachyarrhythmia and gradual decrease in QTc interval during hospitalization which supports the evidence of causal relationship between Loperamide overdose and potentially fatal arrhythmias. It also provided the clue that patient may have congenital long QT syndrome which was unmasked by Loperamide causing ventricular arrhythmias. This case adds one more pearl in the literature to support that Loperamide overdose related cardiac toxicity does exist and it raises concerns over Loperamide abuse in the community.

  8. Life-Threatening Sochi Virus Infections, Russia.

    Science.gov (United States)

    Kruger, Detlev H; Tkachenko, Evgeniy A; Morozov, Vyacheslav G; Yunicheva, Yulia V; Pilikova, Olga M; Malkin, Gennadiy; Ishmukhametov, Aydar A; Heinemann, Patrick; Witkowski, Peter T; Klempa, Boris; Dzagurova, Tamara K

    2015-12-01

    Sochi virus was recently identified as a new hantavirus genotype carried by the Black Sea field mouse, Apodemus ponticus. We evaluated 62 patients in Russia with Sochi virus infection. Most clinical cases were severe, and the case-fatality rate was as high as 14.5%.

  9. A life threatening intracerebral hemorrhage during pregnancy

    OpenAIRE

    Kamala Verma; Sudesh Agrawal

    2015-01-01

    Intracerebral hemorrhage (ICH) during antenatal period is an infrequent but serious complication. This is a case of elderly woman with pregnancy induced hypertension who developed spontaneous ICH during the thirty five week of pregnancy. She presented to our emergency department with altered sensorium, aphasia and hemiparesis. Intracerebral hemorrhage was diagnosed by MRI. Magnetic resonance angiography failed to identify an aneurysm or arteriovenous malformation. She underwent successful em...

  10. Life-Threatening Cardiac Manifestations of Pheochromocytoma

    Directory of Open Access Journals (Sweden)

    Luiz R. Leite

    2010-01-01

    Full Text Available Pheochromocytoma is a catecholamine-secreting tumor of the adrenal glands, usually with benign manifestations, whose typical clinical presentation includes the triad of headache, palpitations and diaphoresis. However, a wide range of signs and symptoms may be present. In the cardiovascular system, the most common signs are labile hypertension and sinus tachycardia. Systolic heart failure and ST-segment deviations mimicking myocardial infarction have also been reported, as well as QT interval prolongation and, rarely, ventricular tachycardia. We describe a challenging diagnosis of pheochromocytoma with many cardiovascular manifestations, which could have been missed due to the absence of typical symptoms.

  11. Loperamide Induced Life Threatening Ventricular Arrhythmia.

    Science.gov (United States)

    Upadhyay, Ankit; Bodar, Vijaykumar; Malekzadegan, Mohammad; Singh, Sharanjit; Frumkin, William; Mangla, Aditya; Doshi, Kaushik

    2016-01-01

    Loperamide is over-the-counter antidiarrheal agent acting on peripherally located μ opioid receptors. It is gaining popularity among drug abusers as opioid substitute. We report a case of a 46-year-old male that was presented after cardiac arrest. After ruling out ischemia, cardiomyopathy, pulmonary embolism, central nervous system pathology, sepsis, and other drug toxicity, we found out that patient was using around 100 mg of Loperamide to control his chronic diarrhea presumably because of irritable bowel syndrome for last five years and consumed up to 200 mg of Loperamide daily for last two days before the cardiac arrest. We hypothesize that the patient's QTc prolongation and subsequent cardiac arrest are due to Loperamide toxicity. Patient experienced gradual resolution of tachyarrhythmia and gradual decrease in QTc interval during hospitalization which supports the evidence of causal relationship between Loperamide overdose and potentially fatal arrhythmias. It also provided the clue that patient may have congenital long QT syndrome which was unmasked by Loperamide causing ventricular arrhythmias. This case adds one more pearl in the literature to support that Loperamide overdose related cardiac toxicity does exist and it raises concerns over Loperamide abuse in the community. PMID:27547470

  12. Cardiovascular Response to Manual Acupuncture Needle Stimulation among Apparently Healthy Nigerian Adults.

    Science.gov (United States)

    Sokunbi, Ganiyu; Maduagwu, Stanley; Jaiyeola, Olabode; Gambo, Hassan; Blasu, Cephas

    2016-06-01

    This study investigated experience with acupuncture needle stimulation of apparently healthy adult Nigerians and the responses of the systolic blood pressure (SBP), diastolic blood pressure, heart rate (HR), and rate pressure products (RPP) to acupuncture at both real acupuncture points relevant to the treatment of cardiovascular disorder and sham acupuncture points not relevant to the treatment of cardiovascular disorder. Seventy-eight participants were randomly placed into three groups: the real acupuncture group (RAG); the sham acupuncture group (SAG); and the control group, with 26 participants per group. Data were collected preintervention, 15 minutes into acupuncture stimulation, postintervention, and 15 minutes after intervention. Changes (postintervention - preintervention scores) in the SBP, HR, and RPP were statistically lower in the RAG than in the SAG. Changes in the DBP showed a significant difference between the SAG and the RAG (p > 0.05). Findings from this study showed that among apparently healthy Nigerian adults, acupuncture needle stimulation at acupoints relevant to cardiovascular disorders was more effective than sham intervention in reducing the SBP, HR, and RPP. Participants reported heaviness, numbness, and increasing pain, but no dizziness, fainting and/or life-threatening side effects, during and after the acupuncture needle stimulation. PMID:27342888

  13. Apparent Solar Tornado - Like Prominences

    CERN Document Server

    Panasenco, Olga; Velli, Marco

    2013-01-01

    Recent high-resolution observations from the Solar Dynamics Observatory (SDO) have reawakened interest in the old and fascinating phenomenon of solar tornado-like prominences. This class of prominences was first introduced by Pettit (1932), who studied them over many years. Observations of tornado prominences similar to the ones seen by SDO had already been documented by Secchi (1877) in his famous "Le Soleil". High resolution and high cadence multiwavelength data obtained by SDO reveal that the tornado-like appearance of these prominences is mainly an illusion due to projection effects. We discuss two different cases where prominences on the limb might appear to have a tornado-like behavior. One case of apparent vortical motions in prominence spines and barbs arises from the (mostly) 2D counterstreaming plasma motion along the prominence spine and barbs together with oscillations along individual threads. The other case of apparent rotational motion is observed in prominence cavities and results from the 3D ...

  14. Development of a drug safety ePlatform for physicians, pharmacists, and consumers based on post-marketing adverse events

    OpenAIRE

    Keith B. Hoffman; Brian M. Overstreet; Murali Doraiswamy, P.

    2013-01-01

    Rigorous clinical trials under the watchful eye of regulators remain the cornerstone of drug safety. However, the emergence of serious and life-threatening Adverse Events (AEs) across best-selling drug classes [sometimes many years after winning Food and Drug Administration (FDA) approval] underscores the limitations of current clinical trial processes and reinforces the need for careful post-approval pharmacovigilance. The FDA’s sizeable repository of patient case reports linking AEs to appr...

  15. Wormhole Thermodynamics at Apparent Horizons

    OpenAIRE

    Jamil, Mubasher; Akbar, M

    2009-01-01

    In this paper, we discuss the thermodynamic properties of the evolving Lorentzian wormhole. For the shape function $b(r) = r_{0}^2/r$, it is shown that the wormhole spacetime admits two apparent horizons, the inner and the outer one. The inner horizon expands while the outer contracts with the passage of time. Corresponding to these horizons, we have three types of wormholes, regular, extreme and the naked wormholes. Moreover, it is shown that the Einstein field equations can be rewritten as ...

  16. Cosmological and black hole apparent horizons

    CERN Document Server

    Faraoni, Valerio

    2015-01-01

    This book overviews the extensive literature on apparent cosmological and black hole horizons. In theoretical gravity, dynamical situations such as gravitational collapse, black hole evaporation, and black holes interacting with non-trivial environments, as well as the attempts to model gravitational waves occurring in highly dynamical astrophysical processes, require that the concept of event horizon be generalized. Inequivalent notions of horizon abound in the technical literature and are discussed in this manuscript. The book begins with a quick review of basic material in the first one and a half chapters, establishing a unified notation. Chapter 2 reminds the reader of the basic tools used in the analysis of horizons and reviews the various definitions of horizons appearing in the literature. Cosmological horizons are the playground in which one should take baby steps in understanding horizon physics. Chapter 3 analyzes cosmological horizons, their proposed thermodynamics, and several coordinate systems....

  17. Precursory specialties of apparent stresses in Yunnan earthquake series

    Institute of Scientific and Technical Information of China (English)

    LIU Hong-gui; LIU Jie; DING Ye-ling; SUN Ye-jun; YU Xin

    2006-01-01

    On the basis of the assumption that ω2 model accords with source displacement spectra, we have obtained the mathematical expressions for calculating apparent stresses of moderate-small shocks from low-frequency flat level and comer frequency. By using digital seismic records, apparent stress values are calculated for 823 moderate-small shocks of 4 earthquake series in Yunnan area following corrections for instrument response, propagation influence and site effect. The results show that for the 4 earthquake series in Yunnan area, apparent stress hints precursory information, which means that if a moderate-small shock occurs with apparent stress larger than 1 MPa in an earthquake series, a moderate-strong earthquake will occur afterwards; and if there is not moderate-small shock with apparent stress larger than 1 MPa after a moderate-strong event in an earthquake series, strong aftershock will not occur. The research also indicates that the average apparent stress value is 0.8 MPa in Yunnan area, therefore, apparent stress is not obviously related to seismic magnitude.

  18. Partner experiences of "near-miss" events in pregnancy and childbirth in the UK: a qualitative study.

    Directory of Open Access Journals (Sweden)

    Lisa Hinton

    Full Text Available OBJECTIVE: Severe life-threatening complications in pregnancy that require urgent medical intervention are commonly known as "near-miss" events. Although these complications are rare (1 in 100 births, there are potentially 8,000 women and their families in the UK each year who live through a life-threatening emergency and its aftermath. Near-miss obstetric emergencies can be traumatic and frightening for women, and their impact can last for years. There is little research that has explored how these events impact on partners. The objective of this interview study was to explore the impact of a near-miss obstetric emergency, focusing particularly on partners. DESIGN: Qualitative study based on narrative interviews, video and audio recorded and transcribed for analysis. A qualitative interpretative approach was taken, combining thematic analysis with constant comparison. The analysis presented here focuses on the experiences of partners. PARTICIPANTS: Maximum variation sample included 35 women, 10 male partners, and one lesbian partner who had experienced a life-threatening obstetric emergency. SETTING: Interviews were conducted in participants' own homes. RESULTS: In the hospital, partner experiences were characterized by powerlessness and exclusion. Partners often found witnessing the emergency shocking and distressing. Support (from family or staff was very important, and clear, honest communication from medical staff highly valued. The long-term emotional effects for some were profound; some experienced depression, flashbacks and post-traumatic stress disorder months and years after the emergency. These, in turn, affected the whole family. Little support was felt to be available, nor acknowledgement of their ongoing distress. CONCLUSION: Partners, as well as women giving birth, can be shocked to experience a life-threatening illness in childbirth. While medical staff may view a near-miss as a positive outcome for a woman and her baby, there

  19. Defining the problem, main objective, and strategies of medical management in mass-casualty incidents caused by terrorist events.

    Science.gov (United States)

    Ashkenazi, Itamar; Kessel, Boris; Olsha, Oded; Khashan, Tawfik; Oren, Meir; Haspel, Jacob; Alfici, Ricardo

    2008-01-01

    Based on the experience of managing > 20 such events during the last decade, the authors' understanding of a mass-casualty incident is that it is an event in which there may be many victims, but only a few that actually suffer from life-threatening injuries. To make an impact on survival, one must identify those who are severely wounded as quickly as possible and offer those patients optimal care. Experienced trauma physicians are the most important resource available to achieve this objective, and they should be allocated to the treatment of seriously injured victims instead of more traditional management roles such as triage and incident manager. PMID:18491667

  20. Distribution of apparent stress in western China

    Institute of Scientific and Technical Information of China (English)

    吴忠良; 黄静; 林碧苍

    2002-01-01

    Distribution of apparent stress in Chinese mainland and its surrounding regions was presented using the NEIC broadband radiated energy catalogue and the Harvard CMT catalogue from January 1987 to December 1998. Due to the limitation on the number of samples, reliable results are only for the western China. It is observed that the average apparent stress in Chinese mainland is 0.8 MPa; The maximum apparent stress to the east of the Tibetan plateau is 2.6 MPa; And the average apparent stress in the north-south seismic belt is more than one time higher than its adjacent regions. Distribution pattern of apparent stress seems to have a large-scale correlation with the cumulative energy release level in the 20th century.

  1. Prevention of Medical Events During Air Travel: A Narrative Review.

    Science.gov (United States)

    Naouri, Diane; Lapostolle, Frederic; Rondet, Claire; Ganansia, Olivier; Pateron, Dominique; Yordanov, Youri

    2016-09-01

    Prior to traveling, and when seeking medical pretravel advice, patients consult their personal physicians. Inflight medical issues are estimated to occur up to 350 times per day worldwide (1/14,000-40,000 passengers). Specific characteristics of the air cabin environment are associated with hypoxia and the expansion of trapped gases into body cavities, which can lead to harm. The most frequent medical events during air travel include abdominal pain; ear, nose, and throat pathologies; psychiatric disorders; and life-threatening events such as acute respiratory failure or cardiac arrest. Physicians need to be aware of the management of these conditions in this unusual setting. Chronic respiratory and cardiovascular diseases are common and are at increased risk of acute exacerbation. Physicians must be trained in these conditions and inform their patients about their prevention. PMID:27267286

  2. Life-threatening angioedema of the tongue: the detection of the RNA of B henselae in the saliva of a male patient and his dog as well as of the DNA of three Bartonella species in the blood of the patient.

    Science.gov (United States)

    Lösch, Barbara; Wank, Rudolf

    2014-01-01

    Non-hereditary angioedema is a common disease with a prevalence between 5% and 19% and approximately half of the patients experience a swelling of the tongue. We report a case of a 49-year-old Caucasian man with a gross life-threatening angioedema of the tongue, whose attacks occurred every 4 weeks. The most frequent causes of angioedema were excluded. We detected DNA and RNA from Bartonella henselae in the blood and saliva of the patient and in the saliva of the patient's hunting dog. Treatment with azithromycin plus minocycline cleared the blood and saliva of RNA and DNA of Bartonella species, and the patient has been free from angioedema for 1 year. None of the therapy modalities used to treat the hereditary form or ACE or allergy-induced angioedema affect the detrimental course caused by Bartonella species. We therefore suggest that a molecular Bartonella test be included in the analysis of angioedema. PMID:24654245

  3. Uncovering undetected hypoglycemic events

    Directory of Open Access Journals (Sweden)

    Unger J

    2012-03-01

    Full Text Available Jeff UngerCatalina Research Institute, Chino, CA, USAAbstract: Hypoglycemia is the rate-limiting factor that often prevents patients with diabetes from safely and effectively achieving their glycemic goals. Recent studies have reported that severe hypoglycemia is associated with a significant increase in the adjusted risks of major macrovascular events, major microvascular events, and mortality. Minor hypoglycemic episodes can also have serious implications for patient health, psychological well being, and adherence to treatment regimens. Hypoglycemic events can impact the health economics of the patient, their employer, and third-party payers. Insulin treatment is a key predictor of hypoglycemia, with one large population-based study reporting an overall prevalence of 7.1% (type 1 diabetes mellitus and 7.3% (type 2 diabetes mellitus in insulin-treated patients, compared with 0.8% in patients with type 2 diabetes treated with an oral sulfonylurea. Patients with type 1 diabetes typically experience symptomatic hypoglycemia on average twice weekly and severe hypoglycemia once annually. The progressive loss of islet cell function in patients with type 2 diabetes results in a higher risk of both symptomatic and unrecognized hypoglycemia over time. Patients with diabetes who become hypoglycemic are also more susceptible to developing defective counter-regulation, also known as hypoglycemia awareness autonomic failure, which is life-threatening and must be aggressively addressed. In patients unable to recognize hypoglycemia symptoms, frequent home monitoring or use of continuous glucose sensors are critical. Primary care physicians play a key role in the prevention and management of hypoglycemia in patients with diabetes, particularly in those requiring intensive insulin therapy, yet physicians are often unaware of the multitude of consequences of hypoglycemia or how to deal with them. Careful monitoring, adherence to guidelines, and use of optimal

  4. Wilcox Group Apparent Thickness, Gulf Coast (wlcxthkg)

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The Apparent Wilcox Group thickness maps are contoured from location and top information derived from the Petroleum Information (PI) Wells database. The Wilcox...

  5. The epidemiology of traumatic event exposure worldwide: results from the World Mental Health Survey Consortium

    Science.gov (United States)

    Benjet, C.; Bromet, E.; Karam, E. G.; Kessler, R. C.; McLaughlin, K. A.; Ruscio, A. M.; Shahly, V.; Stein, D. J.; Petukhova, M.; Hill, E.; Alonso, J.; Atwoli, L.; Bunting, B.; Bruffaerts, R.; Caldas-de-Almeida, J. M.; de Girolamo, G.; Florescu, S.; Gureje, O.; Huang, Y.; Lepine, J. P.; Kawakami, N.; Kovess-Masfety, Viviane; Medina-Mora, M. E.; Navarro-Mateu, F.; Piazza, M.; Posada-Villa, J.; Scott, K. M.; Shalev, A.; Slade, T.; ten Have, M.; Torres, Y.; Viana, M. C.; Zarkov, Z.; Koenen, K. C.

    2016-01-01

    Background Considerable research has documented that exposure to traumatic events has negative effects on physical and mental health. Much less research has examined the predictors of traumatic event exposure. Increased understanding of risk factors for exposure to traumatic events could be of considerable value in targeting preventive interventions and anticipating service needs. Method General population surveys in 24 countries with a combined sample of 68 894 adult respondents across six continents assessed exposure to 29 traumatic event types. Differences in prevalence were examined with cross-tabulations. Exploratory factor analysis was conducted to determine whether traumatic event types clustered into interpretable factors. Survival analysis was carried out to examine associations of sociodemographic characteristics and prior traumatic events with subsequent exposure. Results Over 70% of respondents reported a traumatic event; 30.5% were exposed to four or more. Five types – witnessing death or serious injury, the unexpected death of a loved one, being mugged, being in a life-threatening automobile accident, and experiencing a life-threatening illness or injury – accounted for over half of all exposures. Exposure varied by country, sociodemographics and history of prior traumatic events. Being married was the most consistent protective factor. Exposure to interpersonal violence had the strongest associations with subsequent traumatic events. Conclusions Given the near ubiquity of exposure, limited resources may best be dedicated to those that are more likely to be further exposed such as victims of interpersonal violence. Identifying mechanisms that account for the associations of prior interpersonal violence with subsequent trauma is critical to develop interventions to prevent revictimization. PMID:26511595

  6. Viscous Cosmology and Thermodynamics of Apparent Horizon

    Institute of Scientific and Technical Information of China (English)

    M. Akbar

    2008-01-01

    @@ It is shown that the differential form of Friedmann equations of Friedman-Robertson-Walker (FRW) universe can be recast as a similar form of the first law ThdSh=dE + W dV of thermodynamics at the apparent horizon of FRW universe filled with the viscous fluid.It is also shown that by employing the general expression of temperature Th=|k|/2π=1/2π(r)A(1-(r)A/2H(r)A) associated with the apparent horizon of an FRW universe and assumed that the temperature Tm of the energy inside the apparent horizon is proportional to the horizon temperature Tm = bTh,we are able to show that the generalized second law of thermodynamics holds in the Einstein gravity provided Th-Tm/(r)A≤(p+(P)).

  7. Serious Asthma Events with Fluticasone plus Salmeterol versus Fluticasone Alone

    DEFF Research Database (Denmark)

    Stempel, David A; Raphiou, Ibrahim H; Kral, Kenneth M;

    2016-01-01

    alone for 26 weeks. All the patients had a history of a severe asthma exacerbation in the year before randomization but not during the previous month. Patients were excluded from the trial if they had a history of life-threatening or unstable asthma. The primary safety end point was the first serious......BACKGROUND: The safe and appropriate use of long-acting beta-agonists (LABAs) for the treatment of asthma has been widely debated. In two large clinical trials, investigators found a potential risk of serious asthma-related events associated with LABAs. This study was designed to evaluate the risk...... of administering the LABA salmeterol in combination with an inhaled glucocorticoid, fluticasone propionate. METHODS: In this multicenter, randomized, double-blind trial, adolescent and adult patients (age, ≥12 years) with persistent asthma were assigned to receive either fluticasone with salmeterol or fluticasone...

  8. Mass screenings at mass participation events: MedFest at Special Olympics.

    Science.gov (United States)

    Seidenberg, Peter H; Eggers, Jason L

    2015-01-01

    MedFest events offer preparticipation physical evaluations to Special Olympics athletes. This free service can occur as free-standing events or can take place during Special Olympics Games. The goals of MedFest are to screen for conditions that are potentially life threatening or disabling or may predispose the athlete to injury or illness. The medication, cardiac, and neurologic histories are essential components of the evaluation. The majority of athletes screened during a MedFest event will be cleared for sports participation, but many will require some type of referral for further care. It is important for the organizers of the MedFest to have prearranged protocols to ensure that the athletes efficiently receive the required evaluations.

  9. Rubber friction on (apparently) smooth lubricated surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Mofidi, M; Prakash, B [Division of Machine Elements, Luleaa University of Technology, Luleaa SE-97187 (Sweden); Persson, B N J [IFF, FZ-Juelich, 52425 Juelich (Germany); Albohr, O [Pirelli Deutschland AG, 64733 Hoechst/Odenwald, Postfach 1120 (Germany)

    2008-02-27

    We study rubber sliding friction on hard lubricated surfaces. We show that even if the hard surface appears smooth to the naked eye, it may exhibit short-wavelength roughness, which may make the dominant contribution to rubber friction. That is, the observed sliding friction is mainly due to the viscoelastic deformations of the rubber by the counterface surface asperities. The results presented are of great importance for rubber sealing and other rubber applications involving (apparently) smooth surfaces.

  10. Apparent Directional Scanning for DNA Repair

    OpenAIRE

    Zhao, Tong; Dinner, Aaron R.

    2007-01-01

    Recently it was observed that the DNA repair protein human O6-alkylguanine-DNA alkyltransferase repairs lesions at the 5′ ends of 70-nucleotide single-stranded DNA roughly threefold more frequently than lesions at the 3′ ends. Here, we introduce a coarse-grained model to show how a local asymmetry in binding kinetics (rather than thermodynamics) together with irreversible alkyl transfer can give rise to this apparent bias in sequence scanning. Exploration of the parameter space provides quant...

  11. Life-threatening hyperkalemia: a potentially lethal drug combination.

    Science.gov (United States)

    Juvet, Tristan; Gourineni, Venkata C; Ravi, Sandeep; Zarich, Stuart W

    2013-09-01

    Hyperkalemia is commonly seen in the elderly and is occasionally fatal. Inadvertently combining potassium sparing medications can result in profound hyperkalemia which may result in cardiac dysrhythmias, especially in the setting of chronic kidney disease. An 85 year-old woman on a drug regimen of sotalol, valsartan, spironolactone, and trimethoprim-sulfamethoxazole presented to the emergency department with hypotension and bradycardia. Presumptive treatment for hyperkalemia was started based on her initial electrocardiogram. This diagnosis was later confirmed with a serum potassium value of 10.1 mmol/L. Following pharmacologic treatment, emergency hemodialysis was performed and the patient subsequently recovered. It is known that several drug classes can cause hyperkalemia, with elderly patients at a higher risk of developing this side effect. It is believed that this was a major contributor to the degree of hyperkalemia seen in this patient.

  12. Life-threatening meningitis resulting from transrectal prostate biopsy

    Institute of Scientific and Technical Information of China (English)

    Zhou-Jun Shen; Shan-Wen Chen; Hua Wang; Xie-Lai Zhou; Ju-Ping Zhao

    2005-01-01

    After antibiotic prophylaxis with metronidazole and levofloxacin, a transrectal sextant biopsy was performed under the guide of transrectal ultrasonography (TRUS) for a 75-year-old suspicious patient with prostate adenocarcinoma.Although antibiotics were also given after this procedure, the patient still developed fever, anxious, agrypnia and headache. Blood cultures remained negative. Lumbar puncture was performed and was consistent with Escherichia coli bacterial meningitis.

  13. Subcutaneous mucor zygomycosis with potential life-threatening visceral complication

    Directory of Open Access Journals (Sweden)

    Angeline

    2013-01-01

    Full Text Available A mass in right supraclavicular fossa in a diabetic patient mimicking tuberculosis (TB adenitis that ultimately proved to be subcutaneous zygomycosis. A high degree of clinical suspicion is needed for diagnosis especially when these lesions occur at typical sites for the more common indolent infections like TB. This case is being presented not only because of its rarity, but to emphasize the role of early diagnosis and appropriate treatment to prevent serious complications due to proximity to major structures. Fluconazole was used despite not being the ideal drug, solely due to cost constraints. Our patient responded well. However, we do emphasize that response to fluconazole is the exception rather than the rule.

  14. A life-threatening association of coronary anomalies

    Directory of Open Access Journals (Sweden)

    Devasia T

    2016-10-01

    Full Text Available Anomalous origin of the left coronary artery from the right sinus of Valsalva, even though rare, has been documented well in literature. However the association of this anomaly with coronary fistulae has been rarely reported so far. We report the case of a 76-year-old female who presented to us with exertional dyspnoea. General physical and cardiovascular examination revealed no significant abnormalities. All laboratory investigations were normal. Chest radiograph was normal. Electrocardiogram showed left bundle branch block. Echocardiogram revealed a globally hypokinetic left ventricle with reduced ejection fraction. Coronary angiogram showed anomalous origin of left coronary artery from right coronary sinus along with a small coronary-cameral fistula connecting obtuse marginal artery to left ventricle, there was no significant stenosis of epicardial coronaries. This case report, documents the rare association of an anomalous coronary origin of left coronary artery with coronary fistula.

  15. Life-threatening overdose with lamotrigine, citalopram, and chlorpheniramine

    Directory of Open Access Journals (Sweden)

    Venkatraman N

    2008-01-01

    Full Text Available Lamotrigine is a commonly used agent for seizure control in epilepsy. There are limited data on the adverse effects of lamotrigine in overdose. We report a number of serious side-effects associated with a large overdose of lamotrigine. A 23-year-old female presented to the emergency department after taking an intentional overdose of 9.2 g of lamotrigine, 56 mg of chlorpheniramine, and 220 mg of citalopram. On admission, she had a reduced level of consciousness and electrocardiographic abnormalities; a widened QRS and a prolonged corrected QT (QTc interval. Prompt treatment with early intubation, along with the use of magnesium for cardioprotection and administration of sodium bicarbonate may have aided in a quick recovery with a short intensive care stay and good outcome.

  16. Strongyloides hyper-infection causing life-threatening gastrointestinal bleeding

    Institute of Scientific and Technical Information of China (English)

    Lajos Csermely; Hassan Jaafar; Jorgen Kristensen; Antonio Castella; Waldemar Gorka; Ahmed Ali Chebli; Fawaz Trab; Hussain Alizadeh; Béla Hunyady

    2006-01-01

    A 55-year old male patient was diagnosed with strongyloides hyper-infection with stool analysis and intestinal biopsy shortly after his chemotherapy for myeloma.He was commenced on albendazole anthelmintic therapy. After initiation of the treatment he suffered lifethreatening gastrointestinal (GI) bleeding. Repeated endoscopies showed diffuse multi-focal intestinal bleeding. The patient required huge amounts of red blood cells and plasma transfusions and correction of haemostasis with recombinant activated factor Ⅶ.Abdominal aorto-angiography showed numerous microinferior mesenteric arteries' territories. While the biopsy taken prior to the treatment with albendazole did not show evidence of vasculitis, the biopsy taken after initiation of therapy revealed leukoclastic aggregations around the vessels. These findings suggest that, in addition to direct destruction of the mucosa, vasculitis could be an important additive factor causing the massive GI bleeding during the anthelmintic treatment.This might result from substances released by the worms that have been killed with anthelmintic therapy.Current guidelines advise steroids to be tapered and stopped in case of systematic parasitic infections as they might reduce immunity and precipitate parasitic hyper-infection. In our opinion, steroid therapy might be of value in the management of strongyloides hyperinfection related vasculitis, in addition to the anthelmintic treatment. Indeed, steroid therapy of vasculitis with other means of supportive care resulted in cessation of the bleeding and recovery of the patient.

  17. Life-threatening vascular complications after central venous catheter placement

    Energy Technology Data Exchange (ETDEWEB)

    Wicky, S.; Meuwly, J.-Y.; Doenz, F.; Uske, A.; Schnyder, P.; Denys, A. [Department of Radiology, University Hospital, Lausanne (Switzerland)

    2002-04-01

    The purpose of this retrospective study was to report 11 cases of severe vascular complications after central venous catheter misplacement. For each patient, data collection included body mass index, the diagnosis at admission, the site of the procedure, the type of catheter, coagulation parameters, the imaging modalities performed and the applied treatment. Eight patients had a lesion of the subclavian artery. Brachiocephalic vein perforations were assessed in three more patients. All patients had a chest roentgenogram after the procedure, six a CT examination, and four an angiographic procedure. Seven patients had a body mass index above 30, and 5 patients had coagulation disorders prior to the procedure. Seven patients were conservatively managed, 2 patients died despite resuscitation, 1 patient was treated with a stent graft, and one by superselective embolization. Subclavian or jugular vein temporary catheter positioning is a practical approach. Identification of any iatrogenic perforation of the subclavian artery or central veins urges obtainment a chest roentgenogram and, when required, a chest CT, selective angiograms or venograms. Body mass index superior to 30, previous unsuccessful catheterization attempts, and coagulation factor depletion seemed to account for risk factors. Recognition of clinical and radiological complications is mandatory. (orig.)

  18. Apparent resistivity of azimuthal anisotropy layered media

    Institute of Scientific and Technical Information of China (English)

    阮爱国; 毛桐恩; 李清河; 葛双成

    2002-01-01

    The electric field, equations of boundary conditions and calculation formula of apparent resistivity are derived for azimuthal anisotropy layered media with DC method based on anisotropic Ohm(s law. Taking Schlumberger symmetric system as an example and using recurrence formula of nuclear function, the paper theoretically simulates a model of four layers with the same anisotropy coefficient for each layer. The deep sounding curves of resistivity and the pattern of contours are obtained for the model. The results shows the theoretical formula of this paper is correct, the deep sounding curves not only exhibit the difference of resistivity among layers but also indicate the anisotropy characteristics of layers.

  19. On the frequency-apparent magnitude relations

    Energy Technology Data Exchange (ETDEWEB)

    Tinti, S.; Rimondi, R.; Mulargia, F.

    1987-08-01

    The ''apparent magnitude'' of an earthquake is the observed magnitude value and differs from the true magnitude in virtue of the experimental error. If the error is assumed to be normally distributed with standard deviation sigma, the probability distributions of the two magnitudes may be proven to be in a rather simple relationship, at least for the cases of seismological interest. In fact, there is a significant interval of magnitudes where the suggested approximation in the text holds. The main consequence is that, independently of the assumed basic distribution of the true magnitude, the exceedence frequencies appearing from the observed data are larger than the true ones and therefore their values should be corrected by an appropriate reducing factor.

  20. Distribution of apparent magnetization for Asia

    Institute of Scientific and Technical Information of China (English)

    徐元芳; 安振昌; 黄宝春; V.P.Golovkov; N.M.Rotanova; A.L.Kharitonov

    2000-01-01

    Magsat total field anomalies over Asia were used to construct an equivalent magnetization model, which represents the apparent magnetization distribution within an equivalent layer 40 km thick and correlates well with large-scale tectonics, for example, the Kazakhstan, Tarim, Yangtze, India, Sino-Korea and Indochina blocks. The basin, plain, sea basin, and islands are delineated by magnetization lows whereas the plateau and marine ridge correspond to magnetization highs. The boundary between Tibetan Plateau and India marked by a strong gradient along its length coincides with the Yarlung Zangbo River fault roughly. The Tanlu fault belt is the boundary between positive and negative anomalies. This boundary stretches in southwest direction and joins Sanjiang fault belt. The boundary between the Southeast China block and the Yangtze block is also clearly delineated by the magnetization anomalies. Generally, the magnetization boundaries are consistent with the collisional suture of blocks.

  1. Field signature for apparently superluminal particle motion

    CERN Document Server

    Land, Martin

    2016-01-01

    In the context of Stueckelberg's covariant symplectic mechanics, Horwitz and Aharonovich have proposed a simple mechanism by which a particle traveling below light speed almost everywhere may exhibit a transit time that suggests superluminal motion. This mechanism, which requires precise measurement of the particle velocity, involves a subtle perturbation affecting the particle's recorded time coordinate caused by virtual pair processes. The Stueckelberg framework is particularly well suited to such problems, because it permits pair creation/annihilation at the classical level. In this paper, we study a trajectory of the type proposed by Horwitz and Aharonovich, and derive the Maxwell 4-vector potential associated with the motion. We show that the resulting fields carry a signature associated with the apparent superluminal motion, providing an independent test for the mechanism that does not require direct observation of the trajectory, except at the detector.

  2. Event management

    OpenAIRE

    Urban, Zdeněk

    2013-01-01

    The thesis deals with event management and is formally divided into three sections. The first section provides the theoretical basis for the practical part. It primarily defines the terms event, event management and event marketing. The theoretical part proceeds from the general introduction to more detailed examination of the issue, which includes the classification of event marketing within the marketing and communication mix of the company, the typology of events and explanation of various...

  3. Event management

    OpenAIRE

    Jandová, Dita

    2011-01-01

    The thesis deal with event management. For better insight into this field event management is described on case of management of conference. The thesis has three main parts. In the theoretical part there are definitions of terms like event management, conference and other related terms. Further chapters are concerned with the position of event management in the communication mix, typologies of events and mostly with the crucial aspects of event management. In the second part of the thesis the...

  4. Event management

    OpenAIRE

    Šubrtová, Veronika

    2013-01-01

    This bachelor thesis on the topic event management develops this concept, focuses mainly on the creation of the event and its application in practice. Management, event and event management are described in the theoretical section. The importace of event management in the marketing communications mix is shown subsequently and especially the creation of the event is more detailed described. This is then reflected in the practical part of the thesis, in which the awards gala is planed and orga...

  5. Event management

    OpenAIRE

    Grebíková, Kristýna

    2014-01-01

    The thesis in theoretical part focuses on the concepts of event management and their interaction. The theoretical part focuses on the creation of event planning and marketing strategies, typology of events, and provides a situational analysis, objectives events, defines the target group, plan the resources, establish a budget and will focus on event controlling. The practical part carries theory into practice and deals with the organization of the event in the company TON in Chile. Based on a...

  6. Event marketing

    OpenAIRE

    Pham, Quynh Trang

    2008-01-01

    This study aims to analyze event-marketing activities of the small firm and propose new events. At first the theoretical part describes marketing and communication mix and then especially planning and development of event marketing campaign. Research data were collected by the method of survey to propose the new events. Randomly selected customers were asked to fill the questionnaire. Its results were integrated into the proposal of the new events. The interview was realized with the owner of...

  7. Event management

    OpenAIRE

    Pavléková, Markéta

    2013-01-01

    The main theme of the work is event management, which deals with the social events of various types. Event as a mean of communication is a common part of business strategy today and the organization became a separate industry. Procedures how to implement successful event are the essential part of the work. Organizationally demanding activity of event managers, which includes planning, organizing, staffing, leadership and control is supported by marketing activities, which are described in the...

  8. Event management

    OpenAIRE

    Michňa, Michal

    2011-01-01

    The theoretical part of this thesis deals with event management in general. The stress of its theoretical part is put on relation between event management and the other communication channels usually used by marketing experts in a firm. There is also described a confrontation of event management with processes which are basically used in project management. The theoretical part is mainly concerned with event management and organisation of events. There is a deep description of its prepara...

  9. Event management

    OpenAIRE

    Vomáčková, Kateřina

    2013-01-01

    This thesis deals with event management from theory to practice. First part of the thesis consists of literature review of this topic – from definition of basic terms, through event management’s classification in marketing of a company, to description of different stages of event management process. The second part of the thesis is based on practice – an agency that organized for the third year an event focusing on children and sport, is presented here. Last year of this event including...

  10. Mechanics of Apparent Horizon in Two Dimensional Dilaton Gravity

    CERN Document Server

    Cai, Rong-Gen

    2016-01-01

    In this article, we give a definition of apparent horizon in a two dimensional general dilaton gravity theory. With this definition, we construct the mechanics of the apparent horizon by introducing a quasi-local energy of the theory. Our discussion generalizes the apparent horizons mechanics in general spherically symmetric spactimes in four or higher dimensions to the two dimensional dilaton gravity case.

  11. Event management

    OpenAIRE

    Palkosková, Barbora

    2011-01-01

    The diploma thesis deals with a term of event management and its connection to the event marketing. First part of the work focuses on terms that are superior to event management and those are marketing and marketing mix of 4P´s. Communication mix is than separated into smaller parts, defining the position of event marketing and management among them. Accent is put on the current possibilities of typology and separation of event and its practical use. Issue of events is connected to the...

  12. Pluto-charon mutual events

    International Nuclear Information System (INIS)

    Since 1985, planetary astronomers have been working to take advantage of a once-per-century apparent alignment between Pluto and its satellite, Charon, which has allowed mutual occultation and transit events to be observed. There events, which will cease in 1990, have permitted the first precise determinations of their individual radii, densities, and surface compositions. In addition, information on their surface albedo distributions can be obtained

  13. Event management

    OpenAIRE

    Štefl, Petr

    2011-01-01

    This bachelor thesis on the topic of event management deals with planning, organizing, managing, monitoring and implementation of special social events, termed event. It explains what they mean by this term we can imagine and as you can in terms of typology to distinguish events. Literature review consists of the acquired theoretical knowledge in management, project management and marketing. It describes the principles and procedure in place, we should keep the successful organization of ...

  14. Event management

    OpenAIRE

    Strýhalová, Veronika

    2013-01-01

    The Diploma thesis is focused on the Event management company, which organizes a big family minded sport day and describes its activity plan. The thesis consists three main parts, the first – the teoretic part specifices proffesional terms about an event management. This part also describes different event forms which are focused on the right selection and final strategy, the following control of financial situation and event overall what is in general a part of marketing mixture. The second ...

  15. Event management

    OpenAIRE

    Stružková, Tereza

    2014-01-01

    The main objective of this thesis is based on theoretical knowledge and analysis of the actual implementation event action in congress centre of 4*hotel. Asesment of importance, correctnesand effectivess of the vatious procedures of organizin events and create new complete schematic principle of organizin events Implementation actions will be considered from two sides – from side of the company organizer and from the side of event managment coordinator. All the outputs of these two aspect ...

  16. Quasar Apparent Proper Motion Observed by Geodetic VLBI Networks

    OpenAIRE

    D. S. MacMillan

    2003-01-01

    In our standard geodetic VLBI solutions, we estimate the positions of quasars assuming that their positions do not vary in time. However, in solutions estimating proper motion, a significant number of quasars show apparent proper motion greater than 50 uas/yr. For individual quasars, there are source structure effects that cause apparent proper motion. To examine how coherent the pattern of apparent proper motion is over the sky, we have estimated the vector spherical harmonic components of t...

  17. Event Modeling

    DEFF Research Database (Denmark)

    Bækgaard, Lars

    2001-01-01

    The purpose of this chapter is to discuss conceptual event modeling within a context of information modeling. Traditionally, information modeling has been concerned with the modeling of a universe of discourse in terms of information structures. However, most interesting universes of discourse...... are dynamic and we present a modeling approach that can be used to model such dynamics. We characterize events as both information objects and change agents (Bækgaard 1997). When viewed as information objects events are phenomena that can be observed and described. For example, borrow events in a library can...

  18. Event Modeling

    DEFF Research Database (Denmark)

    Bækgaard, Lars

    2001-01-01

    The purpose of this chapter is to discuss conceptual event modeling within a context of information modeling. Traditionally, information modeling has been concerned with the modeling of a universe of discourse in terms of information structures. However, most interesting universes of discourse...... are dynamic and we present a modeling approach that can be used to model such dynamics.We characterize events as both information objects and change agents (Bækgaard 1997). When viewed as information objects events are phenomena that can be observed and described. For example, borrow events in a library can...

  19. Mutual influences of intermodal visual/tactile apparent motion and auditory motion with uncrossed and crossed arms.

    Science.gov (United States)

    Jiang, Yushi; Chen, Lihan

    2013-01-01

    Intra-modal apparent motion has been shown to be affected or 'captured' by information from another, task-irrelevant modality, as shown in cross-modal dynamic capture effect. Here we created inter-modal apparent motion between visual and tactile stimuli and investigated whether there are mutual influences between auditory apparent motion and inter-modal visual/tactile apparent motion. Moreover, we examined whether and how the spatial remapping between somatotopic and external reference frames of tactile events affect the cross-modal capture between auditory apparent motion and inter-modal visual/tactile apparent motion, by introducing two arm postures: arms-uncrossed and arms-crossed. In Experiment 1, we used auditory stimuli (auditory apparent motion) as distractors and inter-modal visual/tactile stimuli (inter-modal apparent motion) as targets while in Experiment 2 we reversed the distractors and targets. In Experiment 1, we found a general detrimental influence of arms-crossed posture in the task of discrimination of direction in visual/tactile stream, but in Experiment 2, the influence of arms-uncrossed posture played a significant role in modulating the inter-modal visual/tactile stimuli capturing over auditory apparent motion. In both Experiments, the synchronously presented motion streams led to noticeable directional congruency effect in judging the target motion. Among the different modality combinations, tactile to tactile apparent motion (TT) and visual to visual apparent motion (VV) are two signatures revealing the asymmetric congruency effects. When the auditory stimuli were targets, the congruency effect was largest with VV distractors, lowest with TT distractors; the pattern was reversed when the auditory stimuli were distractors. In addition, across both experiments the congruency effect in visual to tactile (VT) and tactile to visual (TV) apparent motion was intermediate between the effect-sizes in VV and TT. We replicated the above findings with a

  20. Improvement of the Earthquake Early Warning System with Wavefield Extrapolation with Apparent Velocity and Direction

    Science.gov (United States)

    Sato, A.; Yomogida, K.

    2014-12-01

    The early warning system operated by Japan Meteorological Agency (JMA) has been available in public since October 2007.The present system is still not effective in cases, that we cannot assume a nearly circular wavefront expansion from a source. We propose a new approach based on the extrapolation of the early observed wavefield alone without estimating its epicenter. The idea is similar to the migration method in exploration seismology, but we use not only the information of wave field at an early stage (i.e., at time T2 in Figure, but also its normal derivatives the difference between T1 and T2), that is, we utilize the apparent velocity and direction of early-stage wave propagation to predict the wavefield later (at T3 in Fig.). For the extrapolation of wavefield, we need a reliable Green's function from the observed point to a target point at which the wave arrives later. Since the complete 3-D wave propagation is extremely complex, particularly in and around Japan of highly heterogeneous structures, we shall consider a phenomenological 2-D Green's function, that is, a wavefront propagates on the surface with a certain apparent velocity and direction of P wave. This apparent velocity and direction may vary significantly depending on, for example, event depth and an area of propagation, so we examined those of P wave propagating in Japan in various situations. For example, the velocity of shallow events in Hokkaido is 7.1km/s while that in Nagano prefecture is about 5.5km/s. In addition, the apparent velocity depends on event depth, 7.1km/s for the depth of 10km and 8.9km/s for 100km in Hokkaido. We also conducted f-k array analyses of adjacent five or six stations where we can accurately estimate the apparent velocity and direction of P wave. For deep events with relatively simple waveforms, they are easily obtained, but we may need site corrections to enhance correlations of waveforms among stations for shallow ones. In the above extrapolation scheme, we can

  1. Multiple weather factors affect apparent survival of European passerine birds.

    Directory of Open Access Journals (Sweden)

    Volker Salewski

    Full Text Available Weather affects the demography of animals and thus climate change will cause local changes in demographic rates. In birds numerous studies have correlated demographic factors with weather but few of those examined variation in the impacts of weather in different seasons and, in the case of migrants, in different regions. Using capture-recapture models we correlated weather with apparent survival of seven passerine bird species with different migration strategies to assess the importance of selected facets of weather throughout the year on apparent survival. Contrary to our expectations weather experienced during the breeding season did not affect apparent survival of the target species. However, measures for winter severity were associated with apparent survival of a resident species, two short-distance/partial migrants and a long-distance migrant. Apparent survival of two short distance migrants as well as two long-distance migrants was further correlated with conditions experienced during the non-breeding season in Spain. Conditions in Africa had statistically significant but relatively minor effects on the apparent survival of the two long-distance migrants but also of a presumably short-distance migrant and a short-distance/partial migrant. In general several weather effects independently explained similar amounts of variation in apparent survival for the majority of species and single factors explained only relatively low amounts of temporal variation of apparent survival. Although the directions of the effects on apparent survival mostly met our expectations and there are clear predictions for effects of future climate we caution against simple extrapolations of present conditions to predict future population dynamics. Not only did weather explains limited amounts of variation in apparent survival, but future demographics will likely be affected by changing interspecific interactions, opposing effects of weather in different seasons, and

  2. The effect of visual apparent motion on audiovisual simultaneity.

    Science.gov (United States)

    Kwon, Jinhwan; Ogawa, Ken-ichiro; Miyake, Yoshihiro

    2014-01-01

    Visual motion information from dynamic environments is important in multisensory temporal perception. However, it is unclear how visual motion information influences the integration of multisensory temporal perceptions. We investigated whether visual apparent motion affects audiovisual temporal perception. Visual apparent motion is a phenomenon in which two flashes presented in sequence in different positions are perceived as continuous motion. Across three experiments, participants performed temporal order judgment (TOJ) tasks. Experiment 1 was a TOJ task conducted in order to assess audiovisual simultaneity during perception of apparent motion. The results showed that the point of subjective simultaneity (PSS) was shifted toward a sound-lead stimulus, and the just noticeable difference (JND) was reduced compared with a normal TOJ task with a single flash. This indicates that visual apparent motion affects audiovisual simultaneity and improves temporal discrimination in audiovisual processing. Experiment 2 was a TOJ task conducted in order to remove the influence of the amount of flash stimulation from Experiment 1. The PSS and JND during perception of apparent motion were almost identical to those in Experiment 1, but differed from those for successive perception when long temporal intervals were included between two flashes without motion. This showed that the result obtained under the apparent motion condition was unaffected by the amount of flash stimulation. Because apparent motion was produced by a constant interval between two flashes, the results may be accounted for by specific prediction. In Experiment 3, we eliminated the influence of prediction by randomizing the intervals between the two flashes. However, the PSS and JND did not differ from those in Experiment 1. It became clear that the results obtained for the perception of visual apparent motion were not attributable to prediction. Our findings suggest that visual apparent motion changes temporal

  3. Event management

    OpenAIRE

    Plechatý, Josef

    2012-01-01

    This theses focused on Event management is divided into two parts. First part includes theoretical knowledge while the second part is strictly practical. The first part is focused on marketing, its importance and basic terms. The chapter about marketing is followed by marketing mix, which is shortly characterized and divided into advertisement, sales promotion, public relations and other elements of the communication mix. The last part is a detailed study of Event marketing which includes th...

  4. Anisotropy of the apparent resistivity variation rate near the epicentral region for strong earthquakes

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The apparent resistivity data of 11 stations observed in or near the epicentral regions for 6 strong earthquakes are processed by the normalized monthly rate method. The result show that in the medium-short and short-imminent terms of earthquake preparation the variation rate of apparent resistivity perpendicular (or near perpendicular) to the direction of maximum principal stress is greater than that parallel (or near parallel) to the direction. Such an-isotropic phenomenon is interpreted as follow: the predominant alignment of cracks containing conductive fluid in the maximum principal stress direction caused the anisotropy of the fluid migration during the dilatancy process in the late period of earthquake preparation and resulted in the anisotropy of true resistivity variation rate for rock (or solid) medium which induced the variation rate anisotropy of apparent resistivity on the ground. The study of this paper provides some seismic examples to show the apparent resistivity anisotropy which may be helpful to study the stress status in or near the source zone in the late period of earthquake preparation of strong events.

  5. Apparent Ionic Charge in Electrolyte and Polyelectrolyte Solutions

    Science.gov (United States)

    Magdelenat, H.; And Others

    1978-01-01

    Compares average displacements of charged particles under thermal motion alone with those obtained by the action of an external electric field to develop a concept of "apparent charge" to approximate actual structural charge in an electrolyte solution. (SL)

  6. Detection of Flux Emergence, Splitting, Merging, and Cancellation of Network Fields. II Apparent Unipolar Flux Change and Cancellation

    CERN Document Server

    Iida, Y; Yokoyama, T

    2015-01-01

    In this second paper in the series, we investigate occurrence frequencies of apparent unipolar processes, cancellation, and emergence of patch structures in quiet regions. Apparent unipolar events are considerably more frequent than cancellation and emergence as per our definition, which is consistent with Lamb et al. (2013). Furthermore, we investigate the frequency distributions of changes in flux during apparent unipolar processes are and found that they concentrate around the detection limit of the analysis. Combining these findings with the results of our previous paper, Iida et al. (2012), that merging and splitting are more dominant than emergence and cancellation, these results support the understanding that apparent unipolar processes are actually interactions with and among patches below the detection limit and that there still are numerous flux interactions between the flux range in this analysis and below the detection limit. We also investigate occurrence frequency distributions of flux decrease ...

  7. Finding Apparent Horizons in Dynamic 3D Numerical Spacetimes

    OpenAIRE

    Anninos, P.; Camarda, K.; Libson, J.; Masso, J.; Seidel, E; Suen, W.

    1996-01-01

    We have developed a general method for finding apparent horizons in 3D numerical relativity. Instead of solving for the partial differential equation describing the location of the apparent horizons, we expand the closed 2D surfaces in terms of symmetric trace--free tensors and solve for the expansion coefficients using a minimization procedure. Our method is applied to a number of different spacetimes, including numerically constructed spacetimes containing highly distorted axisymmetric blac...

  8. Analysis of Apparent Elasticity Constants of Woven Fabrics

    Institute of Scientific and Technical Information of China (English)

    董侠; 张建春; 张燕

    2001-01-01

    The woven fabric can be defined as orthogonal elastomer if the extension force that puts on the fabric is very small. Based on the precondition, the apparent elasticity constants of a woven fabric were analyzed theoretically in the paper. The bias angle (which is between weft yarns and extension direction ) affects apparent elasticity modulus and elasticity coefficient of the fabric in the extension direction. And the experiment describes fluxes of elasticity constants going with the bias angle of the fabric.

  9. Event management

    OpenAIRE

    Myslivcová, Hana Bc.

    2007-01-01

    V práci je popsán teoretický postup při pořádání eventů, který vychází ze zásad projektového řízení. Tyto postupy jsou také aplikovány v praktické realizaci eventu. Následuje výzkum aktuálních trendů v event managementu a výzkum cílových skupin s pomocí dat MML/TGI.

  10. The Relationship Between Religion, Illness and Death in Life Histories of Family Members of Children With Life-Threatening Diseases Historias de vida de familiares de niños con enfermedades graves: relación entre religión, enfermedad y muerte Histórias de vida de familiares de crianças com doenças graves: relação entre religião, doença e morte

    Directory of Open Access Journals (Sweden)

    Regina Szylit Bousso

    2010-04-01

    Full Text Available This qualitative study aimed to get to know the relationship between the experiences of families of children with a life-threatening disease and their religion, illness and life histories. The methodological framework was based on Oral History. The data were collected through interviews and the participants were nine families from six different religions who had lived the experience of having a child with a life-threatening disease. The interviews, held with one or two family members, were transcribed, textualized and, through their analysis, the Vital Tone was elaborated, representing the moral synthesis of each narrative. Three dimensions of spirituality were related to illness and death in their life histories: a Higher Being with a healing power; Development and Maintenance of a Connection with God and Faith Encouraging Optimism. The narratives demonstrated the family's search to attribute meanings to their experiences, based on their religious beliefs.Se trata de una investigación cualitativa con el objetivo de conocer la relación entre las experiencias de familias, con niños que tenían una enfermedad grave, con religión, enfermedad, e historias de sus vidas. El marco metodológico usado fue la Historia Oral. Participaron de este estudio nueve familias practicantes de seis religiones diferentes, las cuales pasaron por la experiencia de tener un niño gravemente enfermo. Las entrevistas, realizadas con uno o dos miembros de la familia del niño, fueron transcritas, textualizadas y, a partir de su análisis, fue elaborado el Tono Vital que representa la síntesis moral de la narración. Tres dimensiones de la religiosidad/espiritualidad fueron relacionadas a la enfermedad y muerte en sus historias de vida: un Ser Superior con Poder de Cura; el Desarrollo y Manutención de una Conexión con Dios y la Fe Incentivando el Optimismo. Las narraciones evidenciaron la búsqueda de la familia, partiendo de sus creencias religiosas, por

  11. Climate control of decadal-scale increases in apparent ages of eogenetic karst spring water

    Science.gov (United States)

    Martin, Jonathan B.; Kurz, Marie J.; Khadka, Mitra B.

    2016-09-01

    Water quantity and quality in karst aquifers may depend on decadal-scale variations in recharge or withdrawal, which we hypothesize could be assessed through time-series measurements of apparent ages of spring water. We tested this hypothesis with analyses of various age tracers (3H/3He, SF6, CFC-11, CFC-12, CFC-113) and selected solute concentrations [dissolved oxygen (DO), NO3, Mg, and SO4] from 6 springs in a single spring complex (Ichetucknee springs) in northern Florida over a 16-yr period. These springs fall into two groups that reflect shallow short (Group 1) and deep long (Group 2) flow paths. Some tracer concentrations are altered, with CFC-12 and CFC-113 concentrations yielding the most robust apparent ages. These tracers show a 10-20-yr monotonic increase in apparent age from 1997 to 2013, including the flood recession that followed Tropical Storm Debby in mid-2012. This increase in age indicates most water discharged during the study period recharged the aquifer within a few years of 1973 for Group 2 springs and 1980 for Group 1 springs. Inverse correlations between apparent age and DO and NO3 concentrations reflect reduced redox state in older water. Positive correlations between apparent age and Mg and SO4 concentrations reflect increased water-rock reactions. Concentrated recharge in the decade around 1975 resulted from nearly 2 m of rain in excess of the monthly average that fell between 1960 and 2014, followed by a nearly 4 m deficit to 2014. This excess rain coincided with two major El Niño events during the maximum cool phase in the Atlantic Multidecadal Oscillation. Although regional water withdrawal increased nearly 5-fold between 1980 and 2005, withdrawals represent only 2-5% of Ichetucknee River flow and are less important than decadal-long variations in precipitation. These results suggest that groundwater management should consider climate cycles as predictive tools for future water resources.

  12. Topography's event

    DEFF Research Database (Denmark)

    Munck Petersen, Rikke

    The aim of the paper is first to discuss how horizon and scale can be understood, secondly how they differ and what they might have in common? If topography can be seen as a way of working with these relations experiences, creations and latencies? Thirdly if diagrams and diagrammatology can bring...... space formation - to stimulate and elaborate the event of conception and topological thinking....

  13. Tortoise Coordinate Transformation on Apparent Horizon of a Dynamical Black Hole

    Science.gov (United States)

    Liu, Xianming; Zhao, Zheng; Liu, Wenbiao

    Thinking of Hawking radiation calculation from a Schwarzschild black hole using Damour-Ruffini method, some key requirements of the tortoise coordinate transformation are pointed out. Extending these requirements to a dynamical black hole, a dynamical tortoise coordinate transformation is proposed. Under this new dynamical tortoise coordinate transformation, Hawking radiation from a Vaidya black hole can be got successfully using Damour-Ruffini method. Moreover, we also find that the radiation should be regarded as originating from the apparent horizon rather than the event horizon at least from the viewpoint of the first law of thermodynamics.

  14. Shape reconstruction from apparent contours theory and algorithms

    CERN Document Server

    Bellettini, Giovanni; Paolini, Maurizio

    2015-01-01

    Motivated by a variational model concerning the depth of the objects in a picture and the problem of hidden and illusory contours, this book investigates one of the central problems of computer vision: the topological and algorithmic reconstruction of a smooth three dimensional scene starting from the visible part of an apparent contour. The authors focus their attention on the manipulation of apparent contours using a finite set of elementary moves, which correspond to diffeomorphic deformations of three dimensional scenes. A large part of the book is devoted to the algorithmic part, with implementations, experiments, and computed examples. The book is intended also as a user's guide to the software code appcontour, written for the manipulation of apparent contours and their invariants. This book is addressed to theoretical and applied scientists working in the field of mathematical models of image segmentation.

  15. Foliation dependence of black hole apparent horizons in spherical symmetry

    CERN Document Server

    Faraoni, Valerio; Firouzjaee, Javad T; Helou, Alexis; Musco, Ilia

    2016-01-01

    Numerical studies of gravitational collapse to black holes make use of apparent horizons, which are intrinsically foliation-dependent. We expose the problem and discuss possible solutions using the Hawking quasilocal mass. In spherical symmetry, we present a physically sensible approach to the problem by restricting to spherically symmetric spacetime slicings. In spherical symmetry the apparent horizons are gauge-independent in any spherically symmetric foliation but physical quantities associated with them, such as surface gravity and temperature, are not. The widely used comoving and Kodama foliations, which are of particular interest, are discussed in detail.

  16. Enhancement of apparent resistance to ethanol in Lactobacillus hilgardii

    OpenAIRE

    Couto, José António; Pina, Cristina; Hogg, Tim

    1997-01-01

    The survival of Lactobacillus hilgardii, a highly ethanol-tolerant organism, after an ethanol challenge at 25% (v/v) for 10 min, increased by several log cycles when cells, grown in the absence of ethanol, were pre-treated with 10% (v/v) ethanol, 15% (v/v) methanol or 2% (v/v) butanol for 4 h. A temperature upshift (25 to 40°C) before ethanol challenge demonstrated a similar enhancement of apparent resistance to ethanol. Ethanol shock enhanced apparent resistance to methanol, butanol and heat...

  17. No apparent lock-in depth of the Laschamp geomagnetic excursion: Evidence from the Malan loess

    Institute of Scientific and Technical Information of China (English)

    ZHU Rixiang; LIU Qingsong; PAN Yongxin; DENG Chenglong; ZHANG Rui; WANG Xianfeng

    2006-01-01

    The first-order chronological framework of the long-term Chinese loess/paleosol sequences was based mainly on magnetostratigraphy. However, there remain arguments on the lock-in ages of the major geomagnetic reversals. This study systematically compared the stratigraphic locations of the Laschamp excursion and Henrich events (H4 at~39 ka and H5 at~48 ka) recorded by the Luochuan loess profile in the central Chinese Loess Plateau. Results show that the Lascchamp excursion is bracketed well by these two cold events, and the corresponding estimated age is between about 41.7-43.7 ka, which is close to the widely accepted age of ~40-41 ka for the excursion.Therefore, our new results do not suggest apparent lock-in effects in the last glacial Malan loess.

  18. Children with fever without apparent source: diagnosis and dilemmas

    NARCIS (Netherlands)

    S.E. Bleeker (Sacha)

    2002-01-01

    textabstractTills thesis describes the results of diagnostic research in young children presenting with fever without apparent source at the emergency department. The study was conducted at the Sophia Children's University Hospital in Rotterdam and the Juliana Children's Hospital in The Hague, both

  19. Studying the cosmological apparent horizon with quasistatic coordinates

    Indian Academy of Sciences (India)

    Rui-Yan Yu; Towe Wang

    2013-02-01

    This article aims at a natural generalization of the static coordinates to the ( + 1)-dimensional Friedmann–Lemaître–Robertson–Walker (FLRW) Universe. After demonstrating a no-go theorem, we put forward the quasistatic coordinates for the FLRW Universe. Then, the quasistatic coordinates are utilized to study the unified first law and the scalar-type perturbations on the cosmological apparent horizon.

  20. A New Theory of Leadership: "Realwert" Versus Apparent Good.

    Science.gov (United States)

    Lang, Donald

    1999-01-01

    "Realwert" ("real good") stems from an understanding of humanity's "raison d'etre"--treating others with respect and dignity. It can be contrasted with "apparent good," a condition wherein one mistakenly thinks real good is being pursued. Drawing on Aquinas and Hodginson, this paper argues for a "realwert" conception of educational leadership. (63…

  1. An Apparent Paradox: Catt's Anomaly

    Science.gov (United States)

    Pieraccini, M.; Selleri, S.

    2013-01-01

    Catt's anomaly is a sort of "thought experiment" (a "gedankenexperiment") where electrons seem to travel at the speed of light. Although its author argued with conviction for many years, it has a clear and satisfactory solution and it can be considered indubitably just an apparent paradox. Nevertheless, it is curious and…

  2. On the apparent horizon in fluid-gravity duality

    NARCIS (Netherlands)

    I. Booth; M.P. Heller; G. Plewa; M. Spalinski

    2011-01-01

    This article develops a computational framework for determining the location of boundary-covariant apparent horizons in the geometry of conformal fluid-gravity duality in arbitrary dimensions. In particular, it is shown up to second order and conjectured to hold to all orders in the gradient expansi

  3. Apparent mineralocorticoid excess: time of manifestation and complications despite treatment

    NARCIS (Netherlands)

    Knops, N.B.; Monnens, L.A.H.; Lenders, J.W.M.; Levtchenko, E.N.

    2011-01-01

    Here we describe the case of a patient followed from birth because of a positive family history for apparent mineralocorticoid excess (AME) in an older brother. The patient, a girl, had normal serum electrolyte and blood pressure measurements in the first months after birth. Not until the age of 11

  4. Apparent Barrier Height in Scanning Tunneling Microscopy Revisited

    DEFF Research Database (Denmark)

    Olesen, L.; Brandbyge, Mads; Sørensen, Mads Reinholdt;

    1996-01-01

    The apparent barrier height phi(ap), that is, the rate of change of the logarithm of the conductance with tip-sample separation in a scanning tunneling microscope (STM), has been measured for Ni, Pt, and Au single crystal surfaces. The results show that phi(ap) is constant until point contact...

  5. Discovery of an Apparent Nova in M81

    Science.gov (United States)

    Hornoch, K.; Alfaro, M. Diaz; Ordonez-Etxeberria, I.; Vaduvescu, O.

    2015-01-01

    We report the discovery of an apparent nova in M81 on a co-added 1600-s narrow-band H-alpha CCD image taken with the 2.5-m Isaac Newton Telescope (INT) + WFC at La Palma under ~2.4" seeing on 2015 Jan. 15.126 UT.

  6. Visual Benefits in Apparent Motion Displays: Automatically Driven Spatial and Temporal Anticipation Are Partially Dissociated.

    Directory of Open Access Journals (Sweden)

    Merle-Marie Ahrens

    Full Text Available Many behaviourally relevant sensory events such as motion stimuli and speech have an intrinsic spatio-temporal structure. This will engage intentional and most likely unintentional (automatic prediction mechanisms enhancing the perception of upcoming stimuli in the event stream. Here we sought to probe the anticipatory processes that are automatically driven by rhythmic input streams in terms of their spatial and temporal components. To this end, we employed an apparent visual motion paradigm testing the effects of pre-target motion on lateralized visual target discrimination. The motion stimuli either moved towards or away from peripheral target positions (valid vs. invalid spatial motion cueing at a rhythmic or arrhythmic pace (valid vs. invalid temporal motion cueing. Crucially, we emphasized automatic motion-induced anticipatory processes by rendering the motion stimuli non-predictive of upcoming target position (by design and task-irrelevant (by instruction, and by creating instead endogenous (orthogonal expectations using symbolic cueing. Our data revealed that the apparent motion cues automatically engaged both spatial and temporal anticipatory processes, but that these processes were dissociated. We further found evidence for lateralisation of anticipatory temporal but not spatial processes. This indicates that distinct mechanisms may drive automatic spatial and temporal extrapolation of upcoming events from rhythmic event streams. This contrasts with previous findings that instead suggest an interaction between spatial and temporal attention processes when endogenously driven. Our results further highlight the need for isolating intentional from unintentional processes for better understanding the various anticipatory mechanisms engaged in processing behaviourally relevant stimuli with predictable spatio-temporal structure such as motion and speech.

  7. Mediating effect of mental disorders in the pathway between life events and mental health services use: results from the Baltimore Epidemiologic Catchment Area study.

    Science.gov (United States)

    Maulik, Pallab K; Eaton, William W; Bradshaw, Catherine P

    2010-03-01

    This study assessed the role of some common mental health conditions as mediators in the pathway between suffering life events and using mental health services. The participants were from the Baltimore Epidemiologic Catchment Area cohort, interviewed in 1993 to 1996 and 2004 to 2005. Longitudinal data analysis was used to identify models with significant mediation. Only alcohol abuse/dependence disorder was a significant mediator in the pathway between suffering a life-threatening illness and using mental health services in a general medical setup. Female gender, being more than 65 years old, prior use of services and availability of health insurance were some of the factors that significantly predicted service use in that model. Some of other factors like social networks and social support, attitudes towards services, and stigma, may play a role in determining service use. Future research should investigate the role of such factors as mediators for mental health service use. PMID:20215995

  8. Event Index - a LHCb Event Search System

    CERN Document Server

    Ustyuzhanin, Andrey; Kazeev, Nikita; Redkin, Artem

    2015-01-01

    LHC experiments generate up to $10^{12}$ events per year. This paper describes Event Index - an event search system. Event Index's primary function is quickly selecting subsets of events from a combination of conditions, such as the estimated decay channel or stripping lines output. Event Index is essentially Apache Lucene optimized for read-only indexes distributed over independent shards on independent nodes.

  9. Fatal thyrocardiac event

    Directory of Open Access Journals (Sweden)

    Samit Kumar Khutia

    2010-01-01

    Full Text Available Atrial fibrillation occurs frequently (2-20% in chronic hyperthyroidism patients. Poorly treated thyrotoxic patients may present with a life-threatening cerebrovascular accident giving little scope to revert the situation. At times, it is difficult to make a patient euthyroid with conventional management. The definitive treatment of choice is 131 I, radioiodine. An adjusted dose of an oral anticoagulant is highly efficacious for the prevention of all types of strokes. Timely intervention by a skilled airway manager with right instruments is the key to success in airway management. A 50-year-old thyrotoxic, semiconscious male presented with a sudden onset of haemiplegia. He had chronic AF, a huge thyroid swelling with gross tracheal deviation and dilated cardiomyopathy. A CT scan showed infarction in the left middle cerebral artery territory. After initial improvement with conservative management, patient′s condition deteriorated in the next 48 h. Repeat CT scan showed increase in the infarct size with haemorrhage and midline shift. Finally, he died despite all resuscitative measures.

  10. Serious Asthma Events with Budesonide plus Formoterol vs. Budesonide Alone.

    Science.gov (United States)

    Peters, Stephen P; Bleecker, Eugene R; Canonica, Giorgio W; Park, Yong B; Ramirez, Ricardo; Hollis, Sally; Fjallbrant, Harald; Jorup, Carin; Martin, Ubaldo J

    2016-09-01

    Background Concerns remain about the safety of adding long-acting β2-agonists to inhaled glucocorticoids for the treatment of asthma. In a postmarketing safety study mandated by the Food and Drug Administration, we evaluated whether the addition of formoterol to budesonide maintenance therapy increased the risk of serious asthma-related events in patients with asthma. Methods In this multicenter, double-blind, 26-week study, we randomly assigned patients, 12 years of age or older, who had persistent asthma, were receiving daily asthma medication, and had had one to four asthma exacerbations in the previous year to receive budesonide-formoterol or budesonide alone. Patients with a history of life-threatening asthma were excluded. The primary end point was the first serious asthma-related event (a composite of adjudicated death, intubation, and hospitalization), as assessed in a time-to-event analysis. The noninferiority of budesonide-formoterol to budesonide was defined as an upper limit of the 95% confidence interval for the risk of the primary safety end point of less than 2.0. The primary efficacy end point was the first asthma exacerbation, as assessed in a time-to-event analysis. Results A total of 11,693 patients underwent randomization, of whom 5846 were assigned to receive budesonide-formoterol and 5847 to receive budesonide. A serious asthma-related event occurred in 43 patients who were receiving budesonide-formoterol and in 40 patients who were receiving budesonide (hazard ratio, 1.07; 95% confidence interval [CI], 0.70 to 1.65]); budesonide-formoterol was shown to be noninferior to budesonide alone. There were two asthma-related deaths, both in the budesonide-formoterol group; one of these patients had undergone an asthma-related intubation. The risk of an asthma exacerbation was 16.5% lower with budesonide-formoterol than with budesonide (hazard ratio, 0.84; 95% CI, 0.74 to 0.94; P=0.002). Conclusions Among adolescents and adults with predominantly

  11. Apparent Dissolution Kinetics of Diatomite in Alkaline Solution

    Institute of Scientific and Technical Information of China (English)

    DU Gaoxiang; L(U) Guocheng; HE Xuwen

    2013-01-01

    The dissolution kinetics of diatomite in alkaline solution is the theoretical basis for the process optimization of alkali-diatomite reaction and its applications.In this study,the dissolution kinetics of diatomite in NaOH solution is investigated.The results indicate that the dissolution reaction fits well the unreacted shrinking core model for solid-liquid heterogeneous reactions.The apparent reaction order for NaOH is 2 and the apparent activation energy for the reaction (Ea) is 28.06 kJ.mol-1.The intra-particle diffusion through the sodium silicate layer is the rate-controlling step.When the dissolution reaction occurs at the interface of unreacted diatomite solid core,the diffusion in the trans-layer (the liquid film around the wetted particle) reduces the rate of whole dissolution process.

  12. Crystalloids in apparent autophagic plastids: remnants of plastids or peroxisomes?

    Science.gov (United States)

    Papini, Alessio; van Doorn, Wouter G

    2015-02-01

    Plant macroautophagy is carried out by autophagosome-type organelles. Recent evidence suggests that plastids also can carry out macroautophagy. The double membrane at the surface of plastids apparently invaginates, forming an intraplastidial space. This space contains a portion of cytoplasm that apparently becomes degraded. Here we report, in Tillandsia sp. and Aechmaea sp., the presence of almost square or diamond-shaped crystalloids inside what seems the intraplastidial space of autophagous plastids. The same type of crystalloids were observed in chloroplasts and other plastids, but were not found in the cytoplasm or the vacuole. Peroxisomes contained smaller and more irregularly shaped crystalloids compared to the ones observed in 'autophagous' plastids. It is hypothesized that plastids are able to sequester chloroplasts and other plastids. PMID:25462964

  13. True arterial system compliance estimated from apparent arterial compliance.

    Science.gov (United States)

    Quick, C M; Berger, D S; Hettrick, D A; Noordergraaf, A

    2000-03-01

    A new method has been developed to estimate total arterial compliance from measured input pressure and flow. In contrast to other methods, this method does not rely on fitting the elements of a lumped model to measured data. Instead, it relies on measured input impedance and peripheral resistance to calculate the relationship of arterial blood volume to input pressure. Generally, this transfer function is a complex function of frequency and is called the apparent arterial compliance. At very low frequencies, the confounding effect of pulse wave reflection disappears, and apparent compliance becomes total arterial compliance. This study reveals that frequency components of pressure and flow below heart rate are generally necessary to obtain a valid estimate of compliance. Thus, the ubiquitous practice of estimating total arterial compliance from a single cardiac cycle is suspect under most circumstances, since a single cardiac cycle does not contain these frequencies. PMID:10784093

  14. The Apparent and Intrinsic Shape of the APM Galaxy Clusters

    CERN Document Server

    Basilakos, S; Manolis, P; Basilakos, Spyros; Maddox, Steve; Plionis, Manolis

    2000-01-01

    We estimate the distribution of intrinsic shapes of APM galaxy clusters fromthe distribution of their apparent shapes. We measure the projected clusterellipticities using two alternative methods. The first method is based onmoments of the discrete galaxy distribution while the second is based onmoments of the smoothed galaxy distribution. We study the performance of bothmethods using Monte Carlo cluster simulations covering the range of APM clusterdistances and including a random distribution of background galaxies. We findthat the first method suffers from severe systematic biases, whereas the secondis more reliable. After excluding clusters dominated by substructure andquantifying the systematic biases in our estimated shape parameters, we recovera corrected distribution of projected ellipticities. We use the non-parametrickernel method to estimate the smooth apparent ellipticity distribution, andnumerically invert a set of integral equations to recover the correspondingdistribution of intrinsic ellipticiti...

  15. Simulating events

    Energy Technology Data Exchange (ETDEWEB)

    Ferretti, C.; Bruzzone, L. [Techint Italimpianti, Milan (Italy)

    2000-06-01

    The Petacalco Marine terminal on the Pacific coast in the harbour of Lazaro Carclenas (Michoacan) in Mexico, provides coal to the thermoelectric power plant at Pdte Plutarco Elias Calles in the port area. The plant is being converted from oil to burn coal to generate 2100 MW of power. The article describes the layout of the terminal and equipment employed in the unloading, coal stacking, coal handling areas and the receiving area at the power plant. The contractor Techint Italimpianti has developed a software system, MHATIS, for marine terminal management which is nearly complete. The discrete event simulator with its graphic interface provides a real-type decision support system for simulating changes to the terminal operations and evaluating impacts. The article describes how MHATIS is used. 7 figs.

  16. Apparent Viscosity of Active Nematics in Poiseuille Flow

    Science.gov (United States)

    Cui, Zhenlu; Su, Jianbing; Zeng, Xiaoming

    2015-09-01

    A Leslie-Erickson continuum hydrodynamic for flowing active nematics has been used to characterize active particle systems such as bacterial suspensions. The behavior of such a system under a plane pressure-driven Poiseuille flow is analyzed. When plate anchoring is tangential and normal, we find the apparent viscosity formula indicating a significant difference between tangential anchoring and normal anchoring conditions for both active rodlike and discoid nematics.

  17. Definition of apparent activation energy on DTG curves

    Directory of Open Access Journals (Sweden)

    A. K. Serikbayeva

    2016-07-01

    Full Text Available The article gives the results of sulphidation oxidized copper ores and tailings with sulfur. Defined by the apparent activation energy in the conditions of heating the mixture of substances interacting with a constant speed by differential thermogravimetry (DTG. It was established that the sulfiding may occur in a kinetic mode , since the interaction is charged, in the presence of liquid and gaseous sulfur , i.e. transport of sulfur to the surface of the mineral is not a limiting process.

  18. Definition of apparent activation energy on DTG curves

    OpenAIRE

    Serikbayeva, A. K.; Zhumashev, K.; N. Sh. Janaliyeva; M. Rakhimberdina

    2016-01-01

    The article gives the results of sulphidation oxidized copper ores and tailings with sulfur. Defined by the apparent activation energy in the conditions of heating the mixture of substances interacting with a constant speed by differential thermogravimetry (DTG). It was established that the sulfiding may occur in a kinetic mode , since the interaction is charged, in the presence of liquid and gaseous sulfur , i.e. transport of sulfur to the surface of the mineral is not a limiting process.

  19. Apparent disapperance of hypernatraemic dehydration from infant deaths in Sheffield.

    Science.gov (United States)

    Sunderland, R; Emery, J L

    1979-09-01

    The death certificates and necropsy reports of the 1115 Sheffield infants who died under 2 years of age in 1969-78 were examined. This study showed the apparent disappearance of deaths with hypernatraemia and in particular deaths presenting as cot deaths. The fall in incidence may be as much the result of an intensive local campaign on child care and infant feeding as of the change in the composition of dried milk for baby feeding.

  20. Information Limits on Identification of Natural Surfaces by Apparent Colour

    OpenAIRE

    Foster, David H.; Nascimento, Sérgio M. C.; Amano, Kinjiro

    2005-01-01

    By adaptational and other mechanisms, the visual system can compensate for moderate changes in the colour of the illumination on a scene. Although the colours of most surfaces are perceived to be constant (“colour constancy”), some are not. The effect of these residual colour changes on the ability of observers to identify surfaces by their apparent colour was determined theoretically from high-resolution hyperspectral images of natural scenes under different daylights with correlated colour ...

  1. Lead-Free Metamaterials with Enormous Apparent Piezoelectric Response.

    Science.gov (United States)

    Zhou, Wanfeng; Chen, Pan; Pan, Qi; Zhang, Xiaotong; Chu, Baojin

    2015-11-01

    Lead-free flexoelectric piezoelectric metamaterials are created by applying an asymmetric chemical reduction to Na1/2 Bi1/2 TiO3 -BaTiO3 ceramics. The reduction induces two gradient-generating mechanisms, curvature structure and chemical inhomogeneity, and enhances the flexoelectric effect. The ceramics behave like piezoelectric materials, exhibiting an enormous and high-temperature stable apparent piezoelectric response, outperforming existing lead-oxide-based piezoelectrics.

  2. Infants' perception of subjective contours from apparent motion.

    Science.gov (United States)

    Yamaguchi, Masami K; Kanazawa, So; Okamura, Hiromi

    2008-01-01

    We examined infants' perception of subjective contours in Subjective-Contour-from-Apparent-Motion (SCAM) stimuli [e.g., Cicerone, C. M., Hoffman, D. D., Gowdy, P. D., & Kim, J. S. (1995). The perception of color from motion. Perception & Psychophysics, 57, 761-777] using the preferential looking technique. The SCAM stimulus is composed of random dots which are assigned two different colors. Circular region assigned one color moved apparently, keeping all dots' location unchanged. In the SCAM stimulus, adults can perceive subjective color spreading and subjective contours in apparent motion (http://c-faculty.chuo-u.ac.jp/ approximately ymasa/okamura/ibd_demo.html). In the present study, we conducted two experiments by using this type of SCAM stimulus. A total of thirty-six 3-8-month-olds participated. In experiment 1, we presented two stimuli to the infants side by side: a SCAM stimulus consisting of different luminance, and a non-SCAM stimulus consisting of isoluminance dots. The results indicated that the 5-8-month-olds showed preference for the SCAM stimuli. In experiments 2 and 3, we confirmed that the infants' preference for the SCAM stimulus was not generated by the local difference and local change made by luminance of dots but by the subjective contours. These results suggest that 5-8-month-olds were able to perceive subjective contours in the SCAM stimuli. PMID:17727955

  3. The apparent state of droplets on a rough surface

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    The factors influencing the state and wetting transition of droplets on a rough surface are both complex and obscure. The change in wetting is directly reflected by changes under the contact condition of the droplets with the surface. The recent study about the wettability of the superhydrophobic surface under the condensing condition arouses the new understanding about the apparent state of droplets on a rough surface. In this work, to validate the existence of droplets in an intermediate state, a microscale pillar topological polydimethylsiloxane (PDMS) surface was manufactured and its wettability under various conditions was studied. According to the experimental data, it is proposed that the wetting state of a rough surface may be embodied using the contact area ratio of a solid/liquid/gas droplet with the projective plane. A general calculation model for the apparent contact angle of droplets is given and expressed diagrammatically. It is found that the measured apparent contact angles of droplets at dif- ferent states on the surface falls within the range predicted by our proposed equation.

  4. Apparent directional spectral emissivity determination of semitransparent materials

    Science.gov (United States)

    Chun-Yang, Niu; Hong, Qi; Ya-Tao, Ren; Li-Ming, Ruan

    2016-04-01

    An inverse estimation method and corresponding measurement system are developed to measure the apparent spectral directional emissivities of semitransparent materials. The normal spectral emissivity and transmissivity serve as input for the inverse analysis. Consequently, the refractive index and absorption coefficient of the semitransparent material could be retrieved by using the pseudo source adding method as the forward method and the stochastic particle swarm optimization algorithm as the inverse method. Finally, the arbitrary apparent spectral directional emissivity of semitransparent material is estimated by using the pseudo source adding method given the retrieval refractive index and absorption coefficient. The present system has the advantage of a simple experimental structure, high accuracy, and excellent capability to measure the emissivity in an arbitrary direction. Furthermore, the apparent spectral directional emissivity of sapphire at 773 K is measured by using this system in a spectral range of 3 μm–12 μm and a viewing range of 0°–90°. The present method paves the way for a new directional spectral emissivity measurement strategy. Project supported by the National Natural Science Foundation of China (Grant Nos. 51476043 and 51576053) and the Foundation for Innovative Research Groups of the National Natural Science Foundation of China (Grant No. 51421063).

  5. Coherent and random apparent stresses in periodically unsteady flows

    Science.gov (United States)

    Kehoe, Anthony Byrd

    1990-08-01

    The transitional flow field downstream of a smooth, symmetrically constricted Sylgard pipe was measured with a two color, two component Laser Doppler Anemometer for both pulsatile and steady flows. Vibrations in the flow system were induced with an exciter/shaker and were monitored with an accelerator. The vibration has little effect on the value of the maximum axial and radial turbulence intensities. A frequency domain signal processing technique to separate the disturbance velocity into coherent and random components was modified to guarantee that the sum of the decomposed velocity components equaled the original disturbance velocity. Results of the velocity separation demonstrated that the velocity disturbances prior to turbulent transition consisted almost entirely of coherent velocity fluctuations. The maximum apparent shear stress was found to occur just after the turbulent transition and consisted almost entirely of the random component. The data suggest that if the absolute magnitude of the apparent stress is the determining factor in red blood cell destruction, then the coherent apparent stress is not a significant destruction mechanism. However, the exact mechanism in hemolysis are not identified.

  6. Low ADAMTS-13 activity during hemorrhagic events with disseminated intravascular coagulation.

    Science.gov (United States)

    Chinen, Yoshiaki; Kuroda, Junya; Ohshiro, Muneo; Shimura, Yuji; Mizutani, Shinsuke; Nagoshi, Hisao; Sasaki, Nana; Nakayama, Ryuko; Kiyota, Miki; Yamamoto-Sugitani, Mio; Kobayashi, Tsutomu; Matsumoto, Yosuke; Horiike, Shigeo; Taniwaki, Masafumi

    2013-04-01

    Disseminated intravascular coagulation (DIC) is a life-threatening complication, and its control is essential for therapeutic success. Recombinant human soluble thrombomodulin alfa (rTM) is a novel therapeutic agent for DIC. The efficacy of rTM in the treatment of DIC is reportedly superior to that of conventional anti-DIC treatments, such as unfractionated heparin or low molecular weight heparin, but hemorrhagic events occasionally interfere with the therapeutic benefits of rTM. We assessed the clinical features of 20 consecutive patients who were given rTM for DIC associated with various hematologic disorders. Eight patients achieved remission of both primary disease and DIC, eight died due to progression of the primary disease, and four died of various hemorrhagic complications. Assessment of 16 biomarkers for coagulation showed that the four patients who died of hemorrhagic complications despite remission of their primary disease showed lower ADAMTS-13 (a disintegrin and metalloproteinase with a thrombospondin Type 1 motif, member 13) plasma activity than other patients (P = 0.016). The optimal cut-off level of ADAMTS-13 for predicting risk of hemorrhagic complications was 42 % (P = 0.007). Plasma ADAMTS-13 activity determined at diagnosis of DIC may help predict the risk of hemorrhagic events during and/or following DIC treatment with hematologic disorders.

  7. Reconciling Horse Welfare, Worker Safety, and Public Expectations: Horse Event Incident Management Systems in Australia.

    Science.gov (United States)

    Fiedler, Julie M; McGreevy, Paul D

    2016-01-01

    Human-horse interactions have a rich tradition and can be highly rewarding, particularly within sport and recreation pursuits, but they can also be dangerous or even life-threatening. In parallel, sport and recreation pursuits involving animals, including horses, are facing an increased level of public scrutiny in relation to the use of animals for these purposes. However, the challenge lies with event organisers to reconcile the expectations of the public, the need to meet legal requirements to reduce or eliminate risks to paid and volunteer workers, and address horse welfare. In this article we explore incident management at horse events as an example of a situation where volunteers and horses can be placed at risk during a rescue. We introduce large animal rescue skills as a solution to improving worker safety and improving horse welfare outcomes. Whilst there are government and horse industry initiatives to improve safety and address animal welfare, there remains a pressing need to invest in a strong communication plan which will improve the safety of workplaces in which humans and horses interact. PMID:26927189

  8. Association of traumatic police event exposure with sleep quality and quantity in the BCOPS Study cohort.

    Science.gov (United States)

    Bond, Jonathan; Hartley, Tara A; Sarkisian, Khachatur; Andrew, Michael E; Charles, Luenda E; Violanti, John M; Burchfiel, Cecil M

    2013-01-01

    Police officers are exposed to traumatic and life-threatening events, which may lead to sleep problems. Prior studies of police officers have found them to have poor sleep quality and reduced sleep time. This study examined associations between traumatic events and sleep quality. Participants were 372 police officers from the Buffalo Cardio-metabolic Occupational Police Stress (BCOPS) Study. Police incidents were measured by the Police Incident Survey; sleep quality and quantity were derived from the Pittsburgh Sleep Quality Index (PSQI). Analysis of covariance (ANCOVA) was used to examine mean PSQI scores across categories of traumatic event frequency. Models were adjusted for age, education and ethnicity and stratified by sex and workload. In men, significant associations were found for the 'shooting of another officer' and sleep quality (p-value = 0.024) and sleep disturbances (p-value = 0.022). In women, seeing more 'abused children' was associated with poorer sleep quality (p-value = 0.050); increasing frequency of 'seeing victims of a serious traffic accident' was associated with shorter sleep duration (p-value = 0.032). Increased frequency of 'seeing dead bodies' was associated with poorer sleep quality (p-value = 0.040) and shorter sleep duration (p-value = 0.048). Among women with a high workload, a significant inverse association was found between 'seeing serious traffic accident victims' and global sleep quality (p-value = 0.031). In conclusion, a significant inverse association between frequency of select traumatic events and sleep quality was found in male and female police officers. The significant events differed by sex. Future research could examine longitudinal associations between career-long traumatic event exposures and sleep quality and how these associations differ by sex.

  9. Events diary

    Science.gov (United States)

    2000-01-01

    as Imperial College, the Royal Albert Hall, the Royal College of Art, the Natural History and Science Museums and the Royal Geographical Society. Under the heading `Shaping the future together' BA2000 will explore science, engineering and technology in their wider cultural context. Further information about this event on 6 - 12 September may be obtained from Sandra Koura, BA2000 Festival Manager, British Association for the Advancement of Science, 23 Savile Row, London W1X 2NB (tel: 0171 973 3075, e-mail: sandra.koura@britassoc.org.uk ). Details of the creating SPARKS events may be obtained from creating.sparks@britassoc.org.uk or from the website www.britassoc.org.uk . Other events 3 - 7 July, Porto Alegre, Brazil VII Interamerican conference on physics education: The preparation of physicists and physics teachers in contemporary society. Info: IACPE7@if.ufrgs.br or cabbat1.cnea.gov.ar/iacpe/iacpei.htm 27 August - 1 September, Barcelona, Spain GIREP conference: Physics teacher education beyond 2000. Info: www.blues.uab.es/phyteb/index.html

  10. Ventricular arrhythmias and risk of death and acute myocardial infarction in apparently healthy subjects of age >or=55 years

    DEFF Research Database (Denmark)

    Sajadieh, A; Nielsen, OW; Rasmussen, Verner;

    2006-01-01

    , and 48-hour ambulatory electrocardiographic monitoring. All patients were followed for up to 5 years. Combined events were defined as all-cause mortality or acute myocardial infarction. A cardiovascular event was defined as cardiovascular death or acute myocardial infarction. In total, 84% had 0 to 10...... arrhythmias were studied in a cohort of middle-aged and elderly subjects without apparent heart disease. Six hundred seventy-eight men and women aged 55 to 75 years without a history of heart disease or stroke were included. Baseline examinations included physical examinations, fasting laboratory testing...

  11. Ultrasonic backscatter from cancellous bone: the apparent backscatter transfer function.

    Science.gov (United States)

    Hoffmeister, Brent K; Mcpherson, Joseph A; Smathers, Morgan R; Spinolo, P Luke; Sellers, Mark E

    2015-12-01

    Ultrasonic backscatter techniques are being developed to detect changes in cancellous bone caused by osteoporosis. Many techniques are based on measurements of the apparent backscatter transfer function (ABTF), which represents the backscattered power from bone corrected for the frequency response of the measurement system. The ABTF is determined from a portion of the backscatter signal selected by an analysis gate of width τw delayed by an amount τd from the start of the signal. The goal of this study was to characterize the ABTF for a wide range of gate delays (1 μs ≤ τd ≤ 6 μs) and gate widths (1 μs ≤ τw ≤ 6 μs). Measurements were performed on 29 specimens of human cancellous bone in the frequency range 1.5 to 6.0 MHz using a broadband 5-MHz transducer. The ABTF was found to be an approximately linear function of frequency for most choices of τd and τw. Changes in τd and τw caused the frequency-averaged ABTF [quantified by apparent integrated backscatter (AIB)] and the frequency dependence of the ABTF [quantified by frequency slope of apparent backscatter (FSAB)] to change by as much as 24.6 dB and 6.7 dB/MHz, respectively. τd strongly influenced the measured values of AIB and FSAB and the correlation of AIB with bone density (-0.95 ≤ R ≤ +0.68). The correlation of FSAB with bone density was influenced less strongly by τd (-0.97 ≤ R ≤ -0.87). τw had a weaker influence than τd on the measured values of AIB and FSAB and the correlation of these parameters with bone density.

  12. Mechanical Components from Highly Recoverable, Low Apparent Modulus Materials

    Science.gov (United States)

    Padula, Santo, II (Inventor); Noebe, Ronald D. (Inventor); Stanford, Malcolm K. (Inventor); DellaCorte, Christopher (Inventor)

    2015-01-01

    A material for use as a mechanical component is formed of a superelastic intermetallic material having a low apparent modulus and a high hardness. The superelastic intermetallic material is conditioned to be dimensionally stable, devoid of any shape memory effect and have a stable superelastic response without irrecoverable deformation while exhibiting strains of at least 3%. The method of conditioning the superelastic intermetallic material is described. Another embodiment relates to lightweight materials known as ordered intermetallics that perform well in sliding wear applications using conventional liquid lubricants and are therefore suitable for resilient, high performance mechanical components such as gears and bearings.

  13. Discovery of an Apparent Nova in M81

    Science.gov (United States)

    Hornoch, K.; Vaduvescu, O.; Gonzalez, A.

    2013-04-01

    We report the discovery of an apparent nova in the M81 galaxy on a co-added 2000-s narrow-band H-alpha CCD image taken with the 2.5-m Isaac Newton Telescope (INT) + WFC at La Palma in ~1.4" seeing on Apr. 5.946 UT. The new object is visible on individual 400-s frames and well visible on the co-added image (see the finding chart linked below), but is not present on numerous narrow-band H-alpha archival images from the INT down to limiting magnitude as faint as H-alpha = 21.7.

  14. Downscaling Smooth Tomographic Models: Separating Intrinsic and Apparent Anisotropy

    Science.gov (United States)

    Bodin, Thomas; Capdeville, Yann; Romanowicz, Barbara

    2016-04-01

    In recent years, a number of tomographic models based on full waveform inversion have been published. Due to computational constraints, the fitted waveforms are low pass filtered, which results in an inability to map features smaller than half the shortest wavelength. However, these tomographic images are not a simple spatial average of the true model, but rather an effective, apparent, or equivalent model that provides a similar 'long-wave' data fit. For example, it can be shown that a series of horizontal isotropic layers will be seen by a 'long wave' as a smooth anisotropic medium. In this way, the observed anisotropy in tomographic models is a combination of intrinsic anisotropy produced by lattice-preferred orientation (LPO) of minerals, and apparent anisotropy resulting from the incapacity of mapping discontinuities. Interpretations of observed anisotropy (e.g. in terms of mantle flow) requires therefore the separation of its intrinsic and apparent components. The "up-scaling" relations that link elastic properties of a rapidly varying medium to elastic properties of the effective medium as seen by long waves are strongly non-linear and their inverse highly non-unique. That is, a smooth homogenized effective model is equivalent to a large number of models with discontinuities. In the 1D case, Capdeville et al (GJI, 2013) recently showed that a tomographic model which results from the inversion of low pass filtered waveforms is an homogenized model, i.e. the same as the model computed by upscaling the true model. Here we propose a stochastic method to sample the ensemble of layered models equivalent to a given tomographic profile. We use a transdimensional formulation where the number of layers is variable. Furthermore, each layer may be either isotropic (1 parameter) or intrinsically anisotropic (2 parameters). The parsimonious character of the Bayesian inversion gives preference to models with the least number of parameters (i.e. least number of layers, and

  15. Discovery of Two Apparent Novae in M81

    Science.gov (United States)

    Hornoch, K.; McCormac, J.; Vaduvescu, O.

    2013-06-01

    We report the discovery of two apparent novae in the M81 galaxy on a co-added 1600-s, narrow-band H-alpha CCD image taken with the 2.5-m Isaac Newton Telescope (INT) + WFC at La Palma in ~1.5" seeing on 2013 June 3.905 UT. The new objects are visible on individual 400-s frames and well visible on the co-added image (see the finding chart linked below), but are not present on numerous narrow-band H-alpha archival images from the INT down to a limiting magnitude as faint as H-alpha = 22.7.

  16. Discovery of Three Apparent Novae in M81

    Science.gov (United States)

    Hornoch, K.; Vaduvescu, O.; Oers, P. van

    2013-02-01

    We report the discovery of three apparent novae in the M81 galaxy on a co-added 3200-s narrow-band H-alpha CCD image taken with the 2.5-m Isaac Newton Telescope (INT) + WFC at La Palma in ~1.4" seeing on Feb. 25.132 UT. The new objects are visible on individual 400-s frames and well visible on the co-added image (see the finding chart linked below), but are not present on numerous narrow-band H-alpha archival images from the INT down to limiting magnitude as faint as H-alpha = 22.5.

  17. Apparent diffusion coefficient correlation with oesophageal tumour stroma and angiogenesis

    Energy Technology Data Exchange (ETDEWEB)

    Aoyagi, Tomoyoshi; Shuto, Kiyohiko; Okazumi, Shinichi; Hayano, Kohichi; Satoh, Asami; Saitoh, Hiroshige; Shimada, Hideaki; Nabeya, Yoshihiro; Matsubara, Hisahiro [Chiba University, Department of Frontier Surgery, Graduate School of Medicine, Chiba (Japan); Kazama, Toshiki [Chiba University, Department of Radiology, Graduate School of Medicine, Chiba (Japan)

    2012-06-15

    Because diffusion-weighted imaging (DWI) can predict the prognosis of patients with oesophageal squamous cell carcinoma (ESCC), we hypothesised that apparent diffusion coefficient (ADC) values might be correlated with the collagen content and tumour angiogenesis. The purpose of this study was to determine the correlation between ADC values of ESCC before treatment and oesophageal tumour stroma and angiogenesis. Seventeen patients with ESCC were enrolled. The ADC values were calculated from the DWI score. Seventeen patients who had undergone oesophagectomy were analysed for tumour stroma, vascular endothelial growth factor (VEGF) and CD34. Tissue collagen was stained with azocarmine and aniline blue to quantitatively analyse the extracellular matrix in cancer stroma. Tissues were stained with VEGF and CD34 to analyse the angiogenesis. The ADC values decreased with stromal collagen growth. We found a negative correlation between the tumour ADC and the amount of stromal collagen (r = -0.729, P = 0.001), i.e. the ADC values decreased with growth of VEGF. We also found a negative correlation between the ADC of the tumours and the amount of VEGF (r = 0.538, P = 0.026). Our results indicated that the ADC value may be a novel prognostic factor and contribute to the treatment of oesophageal cancer. circle Magnetic resonance apparent diffusion coefficient values inversely indicate tumour stromal collagen circle There is also negative correlation between ADCs and vascular endothelial growth factor circle ADC values may contribute to the treatment of oesophageal cancer. (orig.)

  18. The apparently normal galaxy hosts for two luminous quasars

    CERN Document Server

    Bahcall, J N; Bahcall, John N; Schneider, Donald P

    1995-01-01

    HST images (with WFPC2) of PHL~909\\ (z = 0.171) and PG~0052+251\\ (z = 0.155) show that these luminous radio-quiet quasars each occur in an apparently normal host galaxy. The host galaxy of PHL~909 is an elliptical galaxy (\\sim E4) and the host of PG~0052+251 is a spiral (\\sim~Sb). Both host galaxies are several tenths of a magnitude brighter than L^*, the characteristic Schechter luminosity of field galaxies. The images of PHL~909 and PG~0052+251, when compared with HST images of other objects in our sample of 20 luminous, small-redshift (z \\leq 0.30) quasars, show that luminous quasars occur in a variety of environments. The local environments of the luminous quasars range from luminous ellipticals, to apparently normal host galaxies, to complex systems of interacting components, to faint (and as yet undetected) hosts. The bright HII regions of the host galaxy of PG~0052+251 provide an opportunity to measure directly the metallicity of the host of a luminous quasar, to establish an upper limit to the mass of...

  19. Large apparent electric size of solid-state nanopores due to spatially extended surface conduction.

    Science.gov (United States)

    Lee, Choongyeop; Joly, Laurent; Siria, Alessandro; Biance, Anne-Laure; Fulcrand, Rémy; Bocquet, Lydéric

    2012-08-01

    Ion transport through nanopores drilled in thin membranes is central to numerous applications, including biosensing and ion selective membranes. This paper reports experiments, numerical calculations, and theoretical predictions demonstrating an unexpectedly large ionic conduction in solid-state nanopores, taking its origin in anomalous entrance effects. In contrast to naive expectations based on analogies with electric circuits, the surface conductance inside the nanopore is shown to perturb the three-dimensional electric current streamlines far outside the nanopore in order to meet charge conservation at the pore entrance. This unexpected contribution to the ionic conductance can be interpreted in terms of an apparent electric size of the solid-state nanopore, which is much larger than its geometric counterpart whenever the number of charges carried by the nanopore surface exceeds its bulk counterpart. This apparent electric size, which can reach hundreds of nanometers, can have a major impact on the electrical detection of translocation events through nanopores, as well as for ionic transport in biological nanopores.

  20. Why does the apparent mass of a coronal mass ejection increase?

    CERN Document Server

    Feng, Li; Shen, Fang; Shen, Chenglong; Inhester, Bernd; Lu, Lei; Gan, Weiqun

    2015-01-01

    Mass is one of the most fundamental parameters characterizing the dynamics of a coronal mass ejection (CME). It has been found that CME apparent mass measured from the brightness enhancement in coronagraph images shows an increasing trend during its evolution in the corona. However, the physics behind it is not clear. Does the apparent mass gain come from the mass outflow from the dimming regions in the low corona, or from the pileup of the solar wind plasma around the CME when it propagates outwards from the Sun? We analyzed the mass evolution of six CME events. Their mass can increase by a factor of 1.6 to 3.2 from 4 to 15 Rs in the field of view (FOV) of the coronagraph on board the Solar Terrestrial Relations Observatory (STEREO). Over the distance about 7 to 15 Rs, where the coronagraph occulting effect can be negligible, the mass can increase by a factor of 1.3 to 1.7. We adopted the `snow-plough' model to calculate the mass contribution of the piled-up solar wind in the height range from about 7 to 15 ...

  1. Development of a drug safety ePlatform for physicians, pharmacists, and consumers based on post-marketing adverse events

    Directory of Open Access Journals (Sweden)

    Keith B. Hoffman

    2013-07-01

    Full Text Available Rigorous clinical trials under the watchful eye of regulators remain the cornerstone of drug safety. However, the emergence of serious and life-threatening Adverse Events (AEs across best-selling drug classes [sometimes many years after winning Food and Drug Administration (FDA approval] underscores the limitations of current clinical trial processes and reinforces the need for careful post-approval pharmacovigilance. The FDA’s sizeable repository of patient case reports linking AEs to approved drugs is the Adverse Event Reporting System (FAERS. We believe that open and user-friendly access to the millions of case reports in FAERS would help advance the field of post-marketing pharmacovigilance. However, FAERS data are virtually inaccessible to most physicians, pharmacists, and consumers. Accordingly, we have recently launched a big data platform (www.AdverseEvents.com that, unlike previous efforts, provides on-demand, user-friendly, and high-impact access to FAERS data. Bringing the power of big data to regular users, such as clinicians, pharmacists, and patients, is the logical next step in the transformation of health care to a model of shared decision making between consumers and the system.

  2. The Risk Assessment of Adverse Events of Nursing Activities as the Element of Quality Management in Healhcare

    Directory of Open Access Journals (Sweden)

    Wiśniewska Malgorzata Z.

    2015-02-01

    Full Text Available The purpose of the paper is to present MedCARVER+Shock method and Pareto analysis and its usability for the risk assessment of adverse events of nursing activities. 888 activities carried out by all 190 nurses working at the District Hospital X located in Poland were taken into account. During the research the qualitative approach was used. As the result sixteen groups of nursing activities causing the highest risk of adverse events were selected. Special attention required in: admission of a patient to the ward, sterilization, verbal communication with the patient, using of intravenous cannulas, needles, syringes, devices for transfusion of infusion liquids, servicing of hospital rooms, first aid in life-threatening situations, using medical devices and equipment. Ten basic causes of the risk of adverse events were identified, among others: lack of trainings, of modern equipment, of staff, failure to comply with procedures, lack of staff supervision, poor quality of ancillary materials, lack of management commitment. Finally MedCARVER+Shock method and Pareto analysis usability has been confirmed but it appeared that it is time-consuming and requires support from skilled professionals. Several suggestions have been put forward to improve the utility of MedCARVER+Shock.

  3. Energy Dissipation and Apparent Viscosity of Semi-solid Metal during Rheological Processes Part Ⅱ: Apparent Viscosity

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    This study investigated the rheological properties of semi-solid metal. An analytical model of apparent viscosity was built up based on analysis of energy dissipation during rheological processes such as slurry preparing,delivering and model filling. The rheological properties of SSM (semi-solid metal) slurry was described by an analytical model in terms of microstructural parameters, which consist of effective solid fraction, particle size and shape, and flow parameters such as mean velocity, fluctuant velocity and relative velocity between liquid and solid phase. The model was verified in the experiment of A356 alloys with a coaxial double-bucket rheometer. And the maximum relative error between the theoretical value and measured one is less than 10%.The results of experiment and theoretical calculation also indicate that the microstructural parameters and flow parameters are two major factors that affect the apparent viscosity of semi-solid alloys, and fluctuant velocity and relative velocity between liquid and solid phase are the key factors to distinguish between steady and transient rheological properties.

  4. Event-by-event analysis of heavy ion collisions and thermodynamical fluctuations

    OpenAIRE

    Shuryak, E. V.

    1997-01-01

    The event-by-event analysis of heavy ions collisions is becoming possible with advent of large acceptance detectors: it can provide dynamical information which cannot be obtained from inclusive spectra. We identify some observables which can be related to standard thermodynamical fluctuations and therefore may provide information about properties of hadronic matter at the freeze-out stage. Among those are fluctuations of ``apparent temperature'' (the $p_t$ slope), as well as the population of...

  5. Pictet's experiment: The apparent radiation and reflection of cold

    Science.gov (United States)

    Evans, James; Popp, Brian

    1985-08-01

    Towards the end of the eighteenth century it was discovered by Marc-Auguste Pictet of Geneva that cold emanations from a flask of snow could be reflected and focused by mirrors in the same way as the emanations from a heated object. Pictet's discovery had an invigorating effect on research on radiant heat. We sketch the scientific milieu in which Pictet worked, describe the line of investigation that led him to his discovery, and summarize the theoretical explanations offered by Pictet and his contemporaries for this and related experiments. A simple qualitative explanation in modern terms is offered for the apparent radiation and reflection of cold. Finally, detailed directions are provided for replicating the experiment as a demonstration for the lecture hall.

  6. Gravitational energy as dark energy: Cosmic structure and apparent acceleration

    CERN Document Server

    Wiltshire, David L

    2011-01-01

    Below scales of about 100/h Mpc our universe displays a complex inhomogeneous structure dominated by voids, with clusters of galaxies in sheets and filaments. The coincidence that cosmic expansion appears to start accelerating at the epoch when such structures form has prompted a number of researchers to question whether dark energy is a signature of a failure of the standard cosmology to properly account, on average, for the distribution of matter we observe. Here I discuss the timescape scenario, in which cosmic acceleration is understood as an apparent effect, due to gravitational energy gradients that grow when spatial curvature gradients become significant with the nonlinear growth of cosmic structure. I discuss conceptual issues related to the averaging problem, and their impact on the calibration of local geometry to the solutions of the volume-average evolution equations corrected by backreaction, and the question of nonbaryonic dark matter in the timescape framework. I further discuss recent work on ...

  7. Considerations about the apparent superluminal expansions in astrophysics

    International Nuclear Information System (INIS)

    The ortodox models devised to explain the apparent ''superluminal expansions'' observed in astrophysics, and here briefly summarized and discussed together with th experimental data, do not seem to be to much successful. Especially when confronted with the most recent observations, suggesting complicated expansion patterns, even with possible accelerations. At this point it may be, therefore, of some interest to explore the possible alternative models in which actual superluminal motion take place. To prepare the ground one starts from a variational principle, introduces the elements of a tachyon mechanics within special relativity, and argues about the expected behaviour of tachyonic objects when interacting (gravitationally, for instance) among themselves or with ordinary matter. Then the simplest ''superluminal models'', paying particular attention to the observations which they would give rise to are revie wed and developed. It is concluded that some of them appear to be physically acceptable and are statistically favoured with respect to the ortodox ones

  8. When luminance increment thresholds depend on apparent lightness.

    Science.gov (United States)

    Maertens, Marianne; Wichmann, Felix A

    2013-05-31

    A fundamental question in visual perception research is whether the sensitivity to stimulus differences is limited by the sensory representation of the external stimulus, that is, the proximal stimulus, or by its perceptual representation, i.e., stimulus appearance. In the domain of lightness perception, the question translates into whether discrimination thresholds depend on the local luminance in the retinal image or on the apparent lightness of the corresponding image region. The majority of findings seem to indicate that sensitivity is limited by the sensory stimulus representation, which would imply different mechanisms for stimulus discrimination and appearance. We think this conclusion needs to be qualified. We report data suggesting that the relationship between discrimination and appearance judgments depends on how exactly they are being measured. We propose a theoretical account that provides a common mechanism for appearance and sensitivity. An interesting corollary of this model is that it also accounts for the perceptual phenomenon of assimilation.

  9. Apparent diffusion coefficient measurements in progressive supranuclear palsy

    International Nuclear Information System (INIS)

    We measured the apparent diffusion coefficient (ADC), using diffusion-weighted imaging (DWI) and signal intensity on T2-weighted MRI in the cerebral white matter of patients with progressive supranuclear palsy (PSP) and age-matched normal subjects. In PSP, ADC in the prefrontal and precentral white matter was significantly higher than in controls. There was no significant difference in signal intensity on T2-weighted images. The ADC did correlate with signal intensity. The distribution of the elevation of ADC may be the consequence of underlying pathological changes, such as neurofibrillary tangles or glial fibrillary tangles in the cortex. Our findings suggest that ADC measurement might be useful for demonstrating subtle neuropathological changes. (orig.)

  10. Apparent diffusion coefficient measurements in progressive supranuclear palsy

    Energy Technology Data Exchange (ETDEWEB)

    Ohshita, T.; Oka, M.; Imon, Y.; Yamaguchi, S.; Mimori, Y.; Nakamura, S. [Hiroshima Univ. (Japan). School of Medicine

    2000-09-01

    We measured the apparent diffusion coefficient (ADC), using diffusion-weighted imaging (DWI) and signal intensity on T2-weighted MRI in the cerebral white matter of patients with progressive supranuclear palsy (PSP) and age-matched normal subjects. In PSP, ADC in the prefrontal and precentral white matter was significantly higher than in controls. There was no significant difference in signal intensity on T2-weighted images. The ADC did correlate with signal intensity. The distribution of the elevation of ADC may be the consequence of underlying pathological changes, such as neurofibrillary tangles or glial fibrillary tangles in the cortex. Our findings suggest that ADC measurement might be useful for demonstrating subtle neuropathological changes. (orig.)

  11. Plant-mediated 'apparent effects' between mycorrhiza and insect herbivores.

    Science.gov (United States)

    Gilbert, Lucy; Johnson, David

    2015-08-01

    Plants mediate indirect 'apparent' effects between above-ground herbivores and below-ground mutualistic mycorrhizal fungi. The herbivore-plant-mycorrhiza continuum is further complicated because signals produced by plants in response to herbivores can be transmitted to other plants via shared fungal networks below ground. Insect herbivores, such as aphids, probably affect the functioning of mycorrhizal fungi by changing the supply of recent photosynthate from plants to mycorrhizas, whereas there is evidence that mycorrhizas affect aphid fitness by changing plant signalling pathways, rather than only through improved nutrition. New knowledge of the transfer of signals through fungal networks between plant species means we now need a better understanding of how this process occurs in relation to the feeding preferences of herbivores to shape plant community composition and herbivore behaviour in nature.

  12. Vitrectomy for bilateral macular schisis without apparent optic disc anomalies

    Science.gov (United States)

    Andonegui, José; Maya, José Ramón; Echeverría, Marta; Alcaine, Araceli

    2016-01-01

    A 78-year-old man complained of bilateral visual acuity loss. Optical coherence tomography examination showed bilateral macular schisis with fluid accumulation in the external retinal layers without vitreous traction. Fundus examination and fluorescein angiography were normal in both eyes. Both eyes were treated by phacoemulsification, intraocular lens implantation, and vitrectomy without laser, gas exchange, or retinal fenestration. Slow and progressive fluid resorption and improvement in VA were observed in both eyes. Macular schisis similar to the one associated with optic disc anomalies is a possibility in patients without apparent disc anomalies. Vitrectomy without laser, gas, or retinal fenestration may be a good therapeutic option even in patients with a PVD preoperatively. PMID:27703873

  13. Galvanic apparent internal impedance: an intrinsic tissue property.

    Science.gov (United States)

    Golberg, Alex; Rabinowitch, Haim D; Rubinsky, Boris

    2009-11-01

    Using basic galvanic cell principles, the ability of tissues to generate electrical current through electrolysis was characterized. Studying Zn/Cu electrolysis in animal organs revealed a fundamental and measurable tissue-specific property - the galvanic apparent internal impedance (GAII), that is most likely related to the salt bridge function of tissues delineated by electrodes. Further to the fundamental knowledge acquired, GAII enables a new diagnostic method to distinguish between tissue types and to determine their health status without a need for expensive calibration, as often required when external power source is used. We demonstrated the GAII sensitivity in detecting tissue ablation with microwave heating or irreversible electroporation. The results open the way for a novel, inexpensive self-powered tissue diagnostic system for a wide range of applications such as minimally invasive tissue health status, ischemia, hydration, real time intra-operative control of minimally invasive surgery, medical imaging, virtual biopsy and many others.

  14. Event Index - an LHCb Event Search System

    CERN Document Server

    Ustyuzhanin, Andrey

    2015-01-01

    During LHC Run 1, the LHCb experiment recorded around 1011 collision events. This paper describes Event Index | an event search system. Its primary function is to quickly select subsets of events from a combination of conditions, such as the estimated decay channel or number of hits in a subdetector. Event Index is essentially Apache Lucene [1] optimized for read-only indexes distributed over independent shards on independent nodes.

  15. Event Index - an LHCb Event Search System

    OpenAIRE

    Ustyuzhanin, Andrey; Artemov, Alexey; Kazeev, Nikita; Redkin, Artem

    2015-01-01

    During LHC Run 1, the LHCb experiment recorded around $10^{11}$ collision events. This paper describes Event Index - an event search system. Its primary function is to quickly select subsets of events from a combination of conditions, such as the estimated decay channel or number of hits in a subdetector. Event Index is essentially Apache Lucene optimized for read-only indexes distributed over independent shards on independent nodes.

  16. Extracting Event Dynamics from Event-by-Event Analysis

    OpenAIRE

    Fu, Jinghua; Liu, Lianshou

    2003-01-01

    The problem of eliminating the statistical fluctuations and extracting the event dynamics from event-by-event analysis is discussed. New moments $G_p$ (for continuous distribution), and $G_{q,p}$ (for anomalous distribution) are proposed, which are experimentally measurable and can eliminate the Poissonian type statistical fluctuations to recover the dynamical moments $C_p$ and $C_{q,p}$. In this way, the dynamical distribution of the event-averaged transverse momentum $\\bar{\\pt}$ can be extr...

  17. On the apparent CO2 absorption by alkaline soils

    Directory of Open Access Journals (Sweden)

    X. Chen

    2014-02-01

    Full Text Available Alkaline soils in the Gubantonggut Desert were recently demonstrated socking away large quantities of CO2 in an abiotic form. This demands a better understanding of abiotic CO2 exchange in alkaline sites. Reaction of CO2 with the moisture or dew in the soil was conjectured as a potential mechanism. The main goal of this study is to determine the extent to which the dew deposition modulates Land–Atmosphere CO2 exchange at highly alkaline sites (pH ~ 10. Experiments were conducted at the most barren sites (canopy coverage 2 fluxes were measured using a micro-lysimeters and an automated flux system (LI-COR, Lincoln, Nebraska, USA, respectively. There is an evident increase of dew deposition in nocturnal colder temperatures and decrease in diurnal warmer temperatures. Variations of soil CO2 flux are almost contrary, but the increase in diurnal warmer temperatures is obscure. It was shown that the accumulation and evaporation of dew in the soil motivates the apparent absorption and release of CO2. It was demonstrated that dew amounts in the soil has an exponential relation with the part in Fc beyond explanations of the worldwide utilized Q10 model. Therefore dew deposition in highly alkaline soils exerted a potential CO2 sink and can partly explain the apparent CO2 absorption. This implied a crucial component in the net ecosystem carbon balance (NECB at alkaline sites which occupies approximately 5% of the Earth's land surface (7 million km. Further explorations for its mechanisms and representativeness over other arid climate systems have comprehensive perspectives in the quaternary research.

  18. Gastrointestinal events with clopidogrel

    DEFF Research Database (Denmark)

    Grove, Erik Lerkevang; Würtz, Morten; Schwarz, Peter;

    2013-01-01

    Clopidogrel prevents cardiovascular events, but has been linked with adverse gastrointestinal (GI) complications, particularly bleeding events.......Clopidogrel prevents cardiovascular events, but has been linked with adverse gastrointestinal (GI) complications, particularly bleeding events....

  19. Creating Special Events

    Science.gov (United States)

    deLisle, Lee

    2009-01-01

    "Creating Special Events" is organized as a systematic approach to festivals and events for students who seek a career in event management. This book looks at the evolution and history of festivals and events and proceeds to the nuts and bolts of event management. The book presents event management as the means of planning, organizing, directing,…

  20. Refractory Pulmonary Edema Caused by Late Pulmonary Vein Thrombosis After Lung Transplantation: A Rare Adverse Event.

    Science.gov (United States)

    Denton, Eve J; Rischin, Adam; McGiffin, David; Williams, Trevor J; Paraskeva, Miranda A; Westall, Glen P; Snell, Greg

    2016-09-01

    After lung transplantation, pulmonary vein thrombosis is a rare, potentially life-threatening adverse event arising at the pulmonary venous anastomosis that typically occurs early and presents as graft failure and hemodynamic compromise with an associated mortality of up to 40%. The incidence, presentation, outcomes, and treatment of late pulmonary vein thrombosis remain poorly defined. Management options include anticoagulant agents for asymptomatic clots, and thrombolytic agents or surgical thrombectomy for hemodynamically significant clots. We present a rare case highlighting a delayed presentation of pulmonary vein thrombosis occurring longer than 2 weeks after lung transplantation and manifesting clinically as graft failure secondary to refractory pulmonary edema. The patient was treated successfully with surgical thrombectomy and remains well. We recommend a high index of suspicion of pulmonary vein thrombosis when graft failure after lung transplantation occurs and is not responsive to conventional therapy, and consideration of investigation with transesophageal echocardiography or computed tomography with venous phase contrast in such patients even more than 2 weeks after lung transplantation.

  1. Contribution of Chlorophyll Fluorescence to the Apparent Reflectance of Vegetation

    Science.gov (United States)

    Campbell, P. K. Entcheva; Middleton, E. M.; Kim, M. S.

    2007-01-01

    Current strategies for monitoring the physiologic status of terrestrial vegetation rely on remote sensing reflectance (R) measurements, whi ch provide estimates of relative vegetation vigor based primarily on chlorophyll content. Vegetation chlorophyll fluorescence (CF) offers a non-destructive alternative and a more direct approach for diagnosis of vegetation stress before a significant reduction in chlorophyll content has occurred. Thus, monitoring of vegetation vigor based on CF may allow earlier stress detection and more accurate carbon sequestra tion estimates, than is possible using R data alone. However, the observed apparent vegetation reflectance (Ra) in reality includes contrib utions from both the reflected and fluoresced radiation. The aim of t his study is to determine the relative R and CF fractions contributing to Ra from the vegetation in the red to near-infrared region of the spectrum. The practical objectives of the study are to: 1) evaluate t he relationship between CF and R at the foliar level for corn, soybean, maple; and 2) for corn, determine if the relationship established f or healthy (optimal N) vegetation changes under N defiiency. To obtai n generally applicable results, experimental measurements were conducted on unrelated crop and tree species (maple, soybean and corn), unde r controlled conditions and a gradient of inorganic N fertilization l evels. Optical R spectra and actively induced CF emissions were obtained on the same foliar samples, in conjunction with measurements of p hotosynthetic function, pigment levels, and C and N content. The comm on spectral trends or similarities were examined. On average, 10-20% of apparent R at 685 nm was actually due to CF. The spectral trends in steady and maximum F varied significantly, with Fs (especially red) showing higher ability for species and treatment separation. The relative contribution of ChF to R varied significantly among species, with maple emitting much higher F amounts, as

  2. Two Qatari siblings with cystic fibrosis and apparent mineralocorticoid excess

    Directory of Open Access Journals (Sweden)

    Khalid Zahraldin

    2015-01-01

    Full Text Available Cystic fibrosis (CF and apparent mineralocorticoid excess (AME syndrome are both autosomal recessive disorders that result from mutations of specific identified genes for each condition. CF is caused by defects in the Cystic fibrosis trans membrane conductance regulator (CFTR gene which encodes for a protein that functions as a chloride channel and regulates the flow of other ions across the apical surface of epithelial cells. AME is due to the deficiency of 11β-hydroxysteroid dehydrogenase type 2 enzyme (11βHSD2, which is responsible for the peripheral inactivation of cortisol to cortisone. Cortisol excess stimulates the mineralocoritoid receptors (MR resulting in intense sodium retention, hypokalemia and hypertension. We report on a consanguineous Arab family, in which two sibs inherited both CF and AME. Gene testing for AME revealed previously unreported mutation in the 11βHSD2 gene. This report draws attention to the importance of recognizing the possibility of two recessive disorders in the same child in complex consanguineous families. Moreover, it provides a unique opportunity to highlight the implications of the coexistence of two genetic disorders on patient care and genetic counseling of the family.

  3. Estimating phosphorus concentrations following alum treatment using apparent settling velocity

    Science.gov (United States)

    Panuska, John; Robertson, Dale M.

    2009-01-01

    he apparent settling velocity (Vs) is a term used in empirical, steady-state, mass-balance lake models to represent the net phosphorus flux from the water column. The Vollenweider (1969) mixed-reactor lake model was rearranged and used to calculate Vs values for total phosphorus (TP) for three lakes treated with alum to reduce the internal flux of P to the water column (Delavan Lake, Wisconsin; Lake Morey, Vermont; and West Twin Lake, Ohio). An analysis of Vs values was conducted using data from these three lakes for both the pre- and post-alum treated conditions. Analysis of Vs values for both the pre- and post-alum conditions in Lake Morey and West Twin Lake resulted in a post-treatment mean Vs value of 7 ± 2.0 m·yr−1. The effect of the alum treatment, although short-lived in Delavan Lake, resulted in a mean post-treatment Vs value of 3.4 ± 0.3 m·yr−1. The consistency in the post-treatment Vs values in Lake Morey and West Twin Lake is used to demonstrate a predictive analysis method for water column TP concentrations in lakes following a successful treatment of the anoxic sediment area with alum. Additional pre- and post-alum in-lake and watershed loading data are needed to advance this concept into a management model.

  4. Discrimination of paediatric brain tumours using apparent diffusion coefficient histograms

    Energy Technology Data Exchange (ETDEWEB)

    Bull, Jonathan G.; Clark, Christopher A. [UCL Institute of Child Health, Imaging and Biophysics Unit, London (United Kingdom); Saunders, Dawn E. [Great Ormond Street Hospital for Children NHS Trust, Department of Radiology, London (United Kingdom)

    2012-02-15

    To determine if histograms of apparent diffusion coefficients (ADC) can be used to differentiate paediatric brain tumours. Imaging of histologically confirmed tumours with pre-operative ADC maps were reviewed (54 cases, 32 male, mean age 6.1 years; range 0.1-15.8 years) comprising 6 groups. Whole tumour ADC histograms were calculated; normalised for volume. Stepwise logistic regression analysis was used to differentiate tumour types using histogram metrics, initially for all groups and then for specific subsets. All 6 groups (5 dysembryoplastic neuroectodermal tumours, 22 primitive neuroectodermal tumours (PNET), 5 ependymomas, 7 choroid plexus papillomas, 4 atypical teratoid rhabdoid tumours (ATRT) and 9 juvenile pilocytic astrocytomas (JPA)) were compared. 74% (40/54) were correctly classified using logistic regression of ADC histogram parameters. In the analysis of posterior fossa tumours, 80% of ependymomas, 100% of astrocytomas and 94% of PNET-medulloblastoma were classified correctly. All PNETs were discriminated from ATRTs (22 PNET and 4 supratentorial ATRTs) (100%). ADC histograms are useful in differentiating paediatric brain tumours, in particular, the common posterior fossa tumours of childhood. PNETs were differentiated from supratentorial ATRTs, in all cases, which has important implications in terms of clinical management. (orig.)

  5. Earth's Climate Sensitivity: Apparent Inconsistencies in Recent Assessments

    Science.gov (United States)

    Schwartz, Stephen E.; Charlson, Robert J.; Kahn, Ralph; Rodhe, Henning

    2014-12-01

    Earth's equilibrium climate sensitivity (ECS) and forcing of Earth's climate system over the industrial era have been re-examined in two new assessments: the Fifth Assessment Report (AR5) of the Intergovernmental Panel on Climate Change (IPCC), and a study by Otto et al. (2013). The ranges of these quantities given in these assessments and also in the Fourth (2007) IPCC Assessment are analyzed here within the framework of a planetary energy balance model, taking into account the observed increase in global mean surface temperature over the instrumental record together with best estimates of the rate of increase of planetary heat content. This analysis shows systematic differences among the several assessments and apparent inconsistencies within individual assessments. Importantly, the likely range of ECS to doubled CO2 given in AR5, 1.5-4.5 K/(3.7 W m-2) exceeds the range inferred from the assessed likely range of forcing, 1.2-2.9 K/(3.7 W m-2), where 3.7 W m-2 denotes the forcing for doubled CO2. Such differences underscore the need to identify their causes and reduce the underlying uncertainties. Explanations might involve underestimated negative aerosol forcing, overestimated total forcing, overestimated climate sensitivity, poorly constrained ocean heating, limitations of the energy balance model, or a combination of effects.

  6. Apparent Optical Properties in Waters Influenced by the Mississippi River

    Science.gov (United States)

    D'Sa, E.; Miller, R. L.; McKee, B. A.; Trzaska, R.

    2002-01-01

    In-water downwelling irradiance (E(sub d)) and upwelling radiance (L(sub u)) were measured in coastal waters influenced by the Mississippi River at wavelengths corresponding to SeaWiFS spectral bands in April of 2000. Results of derived apparent optical properties (AOP's) such as spectral diffise attenuation coefficient for downwelling irradiance (K(sub d)) suggest that they are mainly influenced by phytoplankton chlorophyll. Large variations in chlorophyll concentrations (0.2 to greater than 10 mg per cubic meters) correspond to variations in K(sub d) at 443 nm ranging from about 0.1 to greater than 1.5 per meter. Attenuation values at 443 nm generally peaked (or were minimal at 555 nm) at depths where chlorophyll concentrations were high. Above water remote sensing reflectance R(sub rs) (443) derived from E(sub d) and L(sub u) shows good agreement to surface chlorophyll. Ratios of remote sensing reflectance, R(sub rs)(443/R(sub rs)(555)versus chlorophyll suggests a potential for obtaining a suitable bio-optical algorithm for the region influenced by the Mississippi River.

  7. Knoop Hardness - Apparent Yield Stress Relationship in Ceramics

    Energy Technology Data Exchange (ETDEWEB)

    Swab, Jeffrey J [ORNL; LaSalvia, Jerry [U.S. Army research Laboratory, Adelphi, MD; Wereszczak, Andrew A [ORNL; Strong, Kevin T [ORNL; Danna, Dominic [U.S. Army research Laboratory, Adelphi, MD; Ragan, Meredith E [ORNL; Ritt, Patrick J [ORNL

    2012-01-01

    In Tabor's classical studies of the deformation of metals, the yield stress (Y) and hardness (H) were shown to be related according to H/Y {approx} 3 for complete or fully plastic deformation. Since then it has been anecdotally shown for ceramics that this ratio is <3. Interest exists to explore this further so Hertzian indentation was used to measure the apparent yield stress of numerous ceramics and metals and their results were compared with each material's load-dependent Knoop hardness. The evaluated ceramics included standard reference materials for hardness (silicon nitride and tungsten carbide), silicon carbide, alumina, and glass. Several steel compositions were also tested for comparison. Knoop hardness measurements at 19.6 N (i.e., toward 'complete or fully plastic deformation'), showed that 2 < H/Y < 3 for the metals and 0.8 < H/Y < 1.8 for the glasses and ceramics. Being that H/Y {ne} 3 for the ceramics indicates that Tabor's analysis is either not applicable to ceramics or that full plastic deformation is not achieved with a Knoop indentation or both.

  8. Mixed quotation: The grammar of apparently transparent opacity

    Directory of Open Access Journals (Sweden)

    Emar Maier

    2014-05-01

    Full Text Available The phenomenon of mixed quotation exhibits clear signs of both the apparent transparency of compositional language use and the opacity of pure quotation. I argue that the interpretation of a mixed quotation in- volves the resolution of a metalinguistic presupposition. The leading idea behind my proposal is that a mixed-quoted expression, say, “has an anomalous feature”, means what x referred to with the words ‘has an anomalous feature’. To understand how this solves the paradox, I set up a precise grammatical framework, explicitly connecting various levels of linguistic analysis: phonological forms, categorial syntax, and a dynamic picture of the semantics–pragmatics interface. In this framework I formalize and evaluate a presuppositional account of mixed quotation. Finally, I address the phenomenon of unquotation and argue that it is an essential ingredient for an elegant and empirically adequate analysis of mixed quotation in natural language. http://dx.doi.org/10.3765/sp.7.7 BibTeX info

  9. Microlensing optical depth as a function of source apparent magnitude

    CERN Document Server

    Wood, Alexander

    2007-01-01

    Measurements of the microlensing optical depth, tau, towards the Galactic bulge appear to depend on the method used to obtain them. Those values based on the lensing of red clump giants (RCGs) appear to be significantly lower than those based on the lensing of all stars along the line of sight. This discrepancy is still not understood. Through Monte Carlo simulations, it is found that the discrepancy cannot be explained by a dependance on the flux limits of the two methods. The optical depth is expected to be generally constant as a function of source apparent magnitude for I_0 >~ 13.0, except in the range 13.5 <~ I_0 <~ 15.5. Here many RCGs are detected, causing a significant oscillation in tau. The amplitude of this oscillation is a function of the inclination angle of the Galactic bar, theta_bar, which may thus be constrained. A further constraint comes from a similar dependance of tau with theta_bar: combining the predicted trends with the measured values provides 1-sigma upper limits, which exclude...

  10. Dig-event: let's socialize around events

    OpenAIRE

    Zhao, Zhenzhen; Liu, Ji; Crespi, Noel

    2012-01-01

    International audience Traditional social networks socialize around the contents that have uploaded to these sites and discover interesting contents uploaded by others. In this demo we aim to explore the idea of activity-oriented social networks. We design a novel social networking site called Dig-Event (Do-it-together Event), where people are able to share events through calendar, while discover interesting events shared by others. Our demo has been inspired by previous research on calend...

  11. Apparent Luminosity Function and Statistical Properties of Fast Radio Bursts

    CERN Document Server

    Li, LongBiao; Zhang, ZhiBin; Li, Di; Li, Bing

    2016-01-01

    Fast Radio Bursts (FRBs) are intense radio flashes from the sky that are astonishingly characterized by millisecond durations and Jansky-level flux densities. Only 16 FRBs have been reported in the literature till now. We carry out a statistical analysis on these events. Their mean dispersion measure, after subtracting the contribution from the interstellar medium of our Galaxy, is found to be $\\sim 655 \\; \\rm pc\\,cm^{-3}$, strongly supporting the idea that they are of cosmological origin. Their energy release in radio band spans about three orders of magnitude, with a mean value of $\\sim 6.42\\times10^{38}$ ergs. The radio energy is found to be positively correlated with the observed fluence and the dispersion measure excess, and the fluence also shows a clear positive correlation with the FRB duration. Among all these events, FRBs 010621 and 010724 seem to form a distinct group in a few plots, indicating that there may be at lease two classes of FRBs. More interestingly, although the FRB study is still in a ...

  12. The apparent charge of nanoparticles trapped at a water interface.

    Science.gov (United States)

    Bossa, Guilherme Volpe; Roth, Joseph; Bohinc, Klemen; May, Sylvio

    2016-05-14

    Charged spherical nanoparticles trapped at the interface between water and air or water and oil exhibit repulsive electrostatic forces that contain a long-ranged dipolar and a short-ranged exponentially decaying component. The former are induced by the unscreened electrostatic field through the non-polar low-permittivity medium, and the latter result from the overlap of the diffuse ion clouds that form in the aqueous phase close to the nanoparticles. The magnitude of the long-ranged dipolar interaction is largely determined by the residual charges that remain attached to the air- (or oil-) exposed region of the nanoparticle. In the present work we address the question to what extent the charges on the water-immersed part of the nanoparticle provide an additional contribution to the dipolar interaction. To this end, we model the electrostatic properties of a spherical particle - a nanoparticle or a colloid - that partitions equatorially to the air-water interface, thereby employing nonlinear Poisson-Boltzmann theory in the aqueous solution and accounting for the propagation of the electric field through the interior of the particle. We demonstrate that the apparent charge density on the air-exposed region of the particle, which determines the dipole potential, is influenced by the electrostatic properties in the aqueous solution. We also show that this electrostatic coupling through the particle can be reproduced qualitatively by a simple analytic planar capacitor model. Our results help to rationalize the experimentally observed weak but non-vanishing salt dependence of the forces that stabilize ordered two-dimensional arrays of interface-trapped nanoparticles or colloids. PMID:27049110

  13. Apparent rotation and jazzing in Leviant's Enigma illusion.

    Science.gov (United States)

    Hamburger, Kai

    2007-01-01

    In 1981 Leviant devised Enigma, a figure that elicits perceived rotary motion in the absence of real motion. However, despite its striking appearance there is no good explanation for this motion illusion to date. Gregory (1993 Proceedings of the Royal Society of London B 253 123) pointed out a similarity to MacKay's 'complementary' afterimage in his ray pattern and suggested accommodative fluctuations and small eye movements as a potential origin for these phenomena. Furthermore, Zeki et al (1993 Proceedings of the Royal Society of London B 252 215-222) found PET-activation in response to Enigma in visual area V5 and immediately surrounding areas (called V5 complex) suggesting that the illusory motion could be mediated by the same neurons as real motion. In the experiments reported here, I show that the rotary motion is perceived on coloured as well as achromatic annuli intercepting the radial lines. More importantly, the illusory streaming motion continues to be seen with a cycloplegic lens as well as through a pinhole (ie ruling out transient changes of accommodation), and in the positive after-image (ie in the absence of eye movements). Apparent rotation is strongest with radial inducers impinging at right angles onto the annuli, but persist, although to a lesser degree, when the inducing lines are tilted in opposite directions, non-collinear, or replaced by dotted lines or lines with rounded terminators. For an explanation, the Enigma illusion requires a neural mechanism that uses lines abutting an empty annulus to elicit orthogonal streaming motion in one or the other direction. PMID:17718359

  14. Estimating groundwater velocity using apparent resistivity tomography: A sandbox experiment

    Science.gov (United States)

    Chen, J. L.; Chen, C. H.; Kuo, C. L.; Fen, C. S.; Wu, C. C.

    2016-08-01

    The electrical resistivity tomography (ERT) technique can estimate groundwater velocity to within 5% of the pre-set groundwater velocity. The apparent conductivity obtained by the ERT technique is linearly related to the groundwater conductivity, as described by Archie's law. Gaussian-like profiles of the tracer concentration were demonstrated with the ERT technique, and the estimated dispersion coefficient was between 0.0015 and 0.0051 cm2/sec. In terms of monitoring changes in groundwater conductivity, the ERT technique has two major advantages over monitoring wells: (1) it measures a larger area and provides more representative results; and, (2) it does not withdraw groundwater samples, and therefore does not affect the groundwater flow. The objective of this research is to measure groundwater velocity with the ERT technique using only one well. The experiments in this research were divided into two parts. The first part evaluated the accuracy and repeatability of the ERT technique using a dipole-dipole array, and the second part estimated the groundwater velocity in a sandbox using the ERT technique. The length, width, and height of the sandbox, which was made of acrylic, were 1.5, 5, and 1.0 m, respectively. The ERT sandbox was sequentially filled with 5-cm layers of the silica sand to a total height of 70 cm. A total of 32 electrodes spaced every 5-cm were installed in the center of the sandbox. Three monitoring wells were installed along the line of the electrodes. Both no-flow and constant flow (NaCl solution with electrical conductivity and concentration of 5,000 μs/cm and 2.456 g/L, respectively) tracer experiments were conducted.

  15. Modifiable cardiovascular risk factors among apparently healthy adult Nigerian population - a cross sectional study

    Directory of Open Access Journals (Sweden)

    Gbadamosi Maruf

    2010-01-01

    Full Text Available Abstract Background Cardiovascular disease (CVD remains a major cause of morbidity and a leading contributor to mortality worldwide. Over the next 2 decades, it is projected that there will be a rise in CVD mortality rates in the developing countries, linked to demographic changes and progressive urbanization. Nigeria has witnessed tremendous socio-economic changes and rural-urban migration which have led to the emergence of non-communicable diseases. We set out to determine the prevalence of modifiable CVD risk factors among apparently healthy adult Nigerians. This is a descriptive cross-sectional study carried out at Katsina, northwestern Nigeria from March to May 2006. Subjects for the study were recruited consecutively from local residents, hospital staff and relations of in-patients of the Federal Medical Centre, Katsina using convenience sampling. Socio-demographic information, anthropometric measurements and blood pressure were obtained from the subjects in a standardized manner. Venous samples were collected for necessary investigations and analyzed at the hospital central laboratory. Findings Three hundred subjects (129 males and 171 females with a mean age of 37.6 ± 10.6 (range 18-75 years were studied. Prevalence of the modifiable cardiovascular risk factors screened for were as follows: generalized obesity 21.3% (males 10.9%, females 29.2%, p 0.05, type 2 diabetes mellitus 5.3% (males 5.4%, females 5.3%, p > 0.05, hypercholesterolaemia 28.3% (males 23.3%, females 32.2%, p 0.05, low HDL-cholesterol 59.3% (males 51.9%, females 65%, p 0.05 and metabolic syndrome 22% (males 10.9%, females 30.4%, p Conclusions We found high prevalence of CVD risk factors among apparently healthy adult Nigerians. In order to reduce this high prevalence and prevent subsequent cardiovascular events, encouragement of a healthy lifestyle is suggested.

  16. Reconciling Horse Welfare, Worker Safety, and Public Expectations: Horse Event Incident Management Systems in Australia

    Science.gov (United States)

    Fiedler, Julie M.; McGreevy, Paul D.

    2016-01-01

    Simple Summary Although often highly rewarding, human-horse interactions can also be dangerous. Using examples from equine and other contexts, this article acknowledges the growing public awareness of animal welfare, work underway towards safer equestrian workplaces, and the potential for adapting large animal rescue skills for the purposes of horse event incident management. Additionally, we identity the need for further research into communication strategies that address animal welfare and safety issues that arise when humans and horses interact in the workplace. Abstract Human-horse interactions have a rich tradition and can be highly rewarding, particularly within sport and recreation pursuits, but they can also be dangerous or even life-threatening. In parallel, sport and recreation pursuits involving animals, including horses, are facing an increased level of public scrutiny in relation to the use of animals for these purposes. However, the challenge lies with event organisers to reconcile the expectations of the public, the need to meet legal requirements to reduce or eliminate risks to paid and volunteer workers, and address horse welfare. In this article we explore incident management at horse events as an example of a situation where volunteers and horses can be placed at risk during a rescue. We introduce large animal rescue skills as a solution to improving worker safety and improving horse welfare outcomes. Whilst there are government and horse industry initiatives to improve safety and address animal welfare, there remains a pressing need to invest in a strong communication plan which will improve the safety of workplaces in which humans and horses interact. PMID:26927189

  17. Psychological impact of chronic hepatitis C: Comparison with other stressful life events and chronic diseases

    Institute of Scientific and Technical Information of China (English)

    Laurent Castera; Aymery Constant; Pierre-Henri Bernard; Victor de Ledinghen; Patrice Couzigou

    2006-01-01

    AIM: To examine the psychological impact of chronic hepatitis C (CHC) diagnosis in a large cohort of CHC patients as compared with other stressful life events and chronic diseases carrying a risk of life-threatening complications.METHODS: One hundred and eighty-five outpatients with compensated CHC were asked to self-grade, using a 100-mm visual analogue scale (VAS), the degree of stress caused by the learning of CHC diagnosis and the perceived severity of their disease. Diagnosis-related stress was compared to four other stressful life events and perceived CHC severity was compared to four other common chronic diseases.RESULTS: Learning of CHC diagnosis was considered a major stressful event (mean ± SD scores: 72±25),significantly less than death of a loved-one (89±13,P<0.0001) and divorce (78± 23, P<0.007), but more than job dismissal (68 ± 30, P<0.04) and home removal (26±24, P< 0.0001). CHC was considered a severe disease (74±19), after AIDS (94±08, P<0.001) and cancer (91±11, P<0.001), but before diabetes (66±23,P<0.001) and hypertension (62±20, P<0.001).Perceived CHC severity was not related to the actual severity of liver disease, assessed according to Metavir fibrosis score. In multivariate analysis, diagnosisrelated stress was related to perceived disease severity (P< 0.001), trait anxiety (P< 0.001) and infection through blood transfusion (P< 0.001).CONCLUSION: Our results show the considerable psychological and emotional burden that a diagnosis of CHC represents, even in the absence of significant liver disease. They should be taken into account when announcing a diagnosis of CHC in order to reduce its negative effects.

  18. Keterlibatan Event Stakeholders pada Keberhasilan Event PR

    Directory of Open Access Journals (Sweden)

    Lidya Wati Evelina

    2013-03-01

    Full Text Available The objective of this article is to determine how event organizers collaborate with stakeholders including the media, particular community, sponsors, participants, venue providers, accommodation providers, carteres, legal and finance personnel, production, local trade, transportation providers, government and associations for implementation Public Relations event. This paper discusses about the things that must be done for the cooperation and the benefits of cooperation undertaken. The method used in this paper is qualitative research method based on observations, literature and case studies. The results of this research note that the event organizers or companies can together with the stakeholders (the other party make an event as mutually beneficial Public Relations. This means that all parties can achieve through the event. At the conclusion of an event Public Relations, all stakeholders involved for their own purposes. Event organizer must ensure that all stakeholders work together effectively in accordance with the agreed schedule and budget. One important feature of the agreement is to maintain a good flow of communication according to the needs of its stakeholders. All information is documented to avoid misunderstandings. Collaboration between stakeholders continuously until the event is completed. Discussion of issues that arise during the event takes place between the committee with various stakeholders is an important thing for the evaluation and response to the events that occurred.

  19. The apparency hypothesis applied to a local pharmacopoeia in the Brazilian northeast

    OpenAIRE

    Lozano, Alejandro; de Araújo, Elcida Lima; Medeiros, Maria Franco Trindade; Albuquerque, Ulysses Paulino

    2014-01-01

    Background Data from an ethnobotanical study were analyzed to see if they were in agreement with the biochemical basis of the apparency hypothesis based on an analysis of a pharmacopeia in a rural community adjacent to the Araripe National Forest (Floresta Nacional do Araripe - FLONA) in northeastern Brazil. The apparency hypothesis considers two groups of plants, apparent and non-apparent, that are characterized by conspicuity for herbivores (humans) and their chemical defenses. Methods This...

  20. [Severe laryngitis associated to gastroesophageal reflux].

    Science.gov (United States)

    Botto, Hugo; Antonioli, Cintia; Nieto, Mary; Cocciaglia, Alejandro; Cuestas, Giselle; Roques Revol, Magdalena; López Marti, Jessica; Rodríguez, Hugo

    2014-02-01

    There is a strong association between gastroesophageal reflux and pharyngolaryngeal reflux as factors leading to respiratory disease, manifested as dysphonia, wheezing, coughing, recurrent laryngitis, bronchial obstruction, laryngospasm and apparent life-threatening events (ALTEs). These manifestations can be mild or severe and may sometimes put the patient's life at risk. We present two cases of patients with severe laryngitis who required endotracheal intubation, one of which underwent tracheostomy. The diagnostic methods and their limitations and the patients outcomes are described.

  1. The effect of reversing current deposition on the apparent density of electrolytic copper powder

    Directory of Open Access Journals (Sweden)

    M. G. PAVLOVIC

    2002-01-01

    Full Text Available The possibility of depositing copper powders with different apparent density by changing the shape of reversing current wave is shown. The morphology and crystallinity of powder particles can be varied considerably by changing shape of the reversing current wave and, hence, the apparent density of powders. The relation of apparent density with particle morphology and structure was illustrated.

  2. A comparison of urban heat islands mapped using skin temperature, air temperature, and apparent temperature (Humidex), for the greater Vancouver area.

    Science.gov (United States)

    Ho, Hung Chak; Knudby, Anders; Xu, Yongming; Hodul, Matus; Aminipouri, Mehdi

    2016-02-15

    Apparent temperature is more closely related to mortality during extreme heat events than other temperature variables, yet spatial epidemiology studies typically use skin temperature (also known as land surface temperature) to quantify heat exposure because it is relatively easy to map from satellite data. An empirical approach to map apparent temperature at the neighborhood scale, which relies on publicly available weather station observations and spatial data layers combined in a random forest regression model, was demonstrated for greater Vancouver, Canada. Model errors were acceptable (cross-validated RMSE=2.04 °C) and the resulting map of apparent temperature, calibrated for a typical hot summer day, corresponded well with past temperature research in the area. A comparison with field measurements as well as similar maps of skin temperature and air temperature revealed that skin temperature was poorly correlated with both air temperature (R(2)=0.38) and apparent temperature (R(2)=0.39). While the latter two were more similar (R(2)=0.87), apparent temperature was predicted to exceed air temperature by more than 5 °C in several urban areas as well as around the confluence of the Pitt and Fraser rivers. We conclude that skin temperature is not a suitable proxy for human heat exposure, and that spatial epidemiology studies could benefit from mapping apparent temperature, using an approach similar to the one reported here, to better quantify differences in heat exposure that exist across an urban landscape. PMID:26706765

  3. Just 6 Percent of Chest Pain Cases in ER Are Life-Threatening

    Science.gov (United States)

    ... department and director of medical education at Mount Carmel St. Ann's Hospital, in Westerville, Ohio. Weinstock's own ... chairman, Emergency Department, and director, medical education, Mount Carmel St. Ann's Hospital, Westerville, Ohio. June 13, 2016, ...

  4. Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases

    Science.gov (United States)

    2005-06-23

    Purpura, Schoenlein-Henoch; Graft Versus Host Disease; Anemia, Hemolytic, Autoimmune; Rheumatoid Arthritis; Churg-Strauss Syndrome; Hypersensitivity Vasculitis; Wegener's Granulomatosis; Systemic Lupus Erythematosus; Giant Cell Arteritis; Pure Red Cell Aplasia; Juvenile Rheumatoid Arthritis; Polyarteritis Nodosa; Autoimmune Thrombocytopenic Purpura; Takayasu Arteritis

  5. Gastro-tracheal fistula - unusual and life threatening complication after esophagectomy for cancer: a case report

    Directory of Open Access Journals (Sweden)

    Droissart Raphaël

    2009-11-01

    Full Text Available Abstract Background A gastro-tracheal fistula following esophagectomy for cancer is a rare but potentially lethal complication. We report the successful surgical closure after failed endoscopic treatment, of a gastro-tracheal fistula following esophago-gastrectomy for cancer after induction chemo-radiotherapy. Case presentation A 58 year-old male patient presented with a distal third uT3N1 carcinoma of the esophagus. After induction chemo-radiotherapy, he underwent an esophago-gastrectomy with radical lymphadenectomy and reconstruction by gastric pull-up. Immediate postoperative outcome was uneventful. On the 15th postoperative day however, our patient was readmitted in the Intensive Care Unit with severe bilateral basal pneumonia. Three days later a gastro-tracheal fistula was diagnosed upon gastroscopy and bronchoscopy. His good general condition allowed for an endoscopic primary approach which consisted in the insertion of a covered stent in the trachea along with clipping and glueing of the gastric fistular orifice. Two attempts proved unsuccessful. Conclusion After several weeks of conservative measures, surgical re-intervention through a right thoracotomy with transection of the fistula and closure by primary interrupted sutures of both fistular orifices along with intercostal muscle flap interposition led to excellent patient outcome. Oral feeding was started and our patient was discharged.

  6. Hyperferritinemia as the Diagnostic Clue in Life-Threatening Hemophagocytic Lymphohistiocytosis

    NARCIS (Netherlands)

    Kerzel, S.; Zemlin, M.; Koemhoff, M.; Klaus, G.; Maier, R. F.

    2009-01-01

    We report on a seventeen year old girl with persistent fever of unknown origin. An initial episode of abdominal pain led to laparotomy and appendectomy, which did not reveal any pathological findings. In the course of the next 3 weeks, the girl's general condition progressively deteriorated. Despite

  7. A Rare Cause of Chronic Life Threatening Bleeding in a Girl: The Ulcerated Blind Loops.

    Science.gov (United States)

    Sawant, Abhijeet D; Shah, Rasik; Shah, Nitin; Gupta, Tarun

    2016-01-01

    Ulceration in a blind loop can lead to massive gastrointestinal tract (GIT) bleeding. A 13-year old girl presented with symptomatic melena requiring repeated blood transfusion since childhood. She was an operated case of small bowel atresia in neonatal life. Her upper and lower gastrointestinal endoscopies were normal. Operation showed presence of multiple ulcers in two blind loops (parts of previous side to side anastomosis) and at the anastomotic site. She underwent resection and end-to-end anastomosis of the small bowel leading to complete resolution of melena and anemia. PMID:27170918

  8. Arterial embolization for iatrogenic life-threatening bleeding from subcutaneous hypervascular tumor in prone position

    Institute of Scientific and Technical Information of China (English)

    Seiji Morita; Tomoatsu Tsuji; Toru Sawamoto; Hiromichi Aoki; Naoya Miura; Hiroyuki Otsuka; Sadaki Inokuchi

    2010-01-01

    Performing angiography in the prone position is a difficult technique; however it is useful in some emergency situation. We experienced a 60 years old male who was performed lipoma excision on his back in his family doctor's clinic. Since massive arterial bleeding could not be controlled with manual astriction, he transferred to our hospital in prone position with hemodynamic instability. Operating field was not kept because of massive bleeding; there-fore surgical treatment was impossible. We planed emer-gency arterial embolization (AE) in prone position. Hence we chose the left radial artery for vascular access. The left subclavicle arteriography showed many major and minor feeding arteries from left subclavicular and axillary arteries and a massive extravasation of the contrast medium. Three major feeding arteries were performed AE with gelatin sponge and steel coils. After AE, massive bleeding was controlled.He could discharge from our hospital on the 5th hospital day without any complication. Arterial embolization for lifethreatening bleeding from subcutaneous hypervascular tumor in the prone position is first report to our knowledge,and it is extremely rare. However we thought that this tech-nique is useful for patients who could not turn in the supine position, e.g. massive bleeding during renal biopsy and penetrating trauma from back.

  9. Management of Varicella Gangrenosa: A Life-Threatening Condition from Chickenpox

    Directory of Open Access Journals (Sweden)

    Judith P. M. Schots

    2014-01-01

    Full Text Available Varicella gangrenosa, in which gangrenous ulceration of the skin and/or deeper tissues is seen, is a rare but alarming complication of Varicella infection. An early surgical intervention is generally advised, especially in case of sepsis and/or the presence of large necrotic lesions. We describe a case of a previously healthy 12-month-old boy presenting with sepsis due to Varicella gangrenosa. He presented with moderate lesions of moist gangrene. We treated our patient initially with antibiotics (ceftriaxone and metronidazole and later on flucloxacillin and antiviral therapy (acyclovir whereupon his condition rapidly improved and all skin lesions healed entirely. This report highlights the possibility of conservative treatment and emphasizes the significance of acyclovir in the management of chickenpox complicated by moist gangrene due to bacterial superinfection.

  10. Life-threatening autoimmune hemolytic anemia and idiopathic thrombocytopenic purpura: successful seletive splenic artery embolization

    Directory of Open Access Journals (Sweden)

    matteo molica

    2016-04-01

    Full Text Available Selective splenic artery embolization (SSAE is a nonsurgical intervention characterized by the transcatheter occlusion of the splenic artery and/or its branch vessels using metallic coils or other embolic devices. It has been applied for the management of splenic trauma, hypersplenism with portal hypertension, hereditary spherocytosis, thalassemia and splenic hemangioma. We hereby describe a case of a patient affected by idiopathic thrombocytopenic purpura (ITP and warm auto-immune hemolytic anemia (AIHA both resistant to immunosuppressive and biological therapies, not eligible for a surgical intervention because of her critical conditions. She underwent SSAE and achieved a hematologic complete response within a few days without complications. SSAE is a minimally invasive procedure to date not considered a standard option in the management of AIHA and ITP. However, following the progressive improvement of the techniques, its indications have been extended, with a reduction in morbidity and mortality compared to splenectomy in patients with critical clinical conditions. SSAE was a lifesaving therapeutic approach for our patient and it may represent a real alternative for the treatment of resistant AIHA and ITP patients not eligible for splenectomy.

  11. [The handling of acute life-threatening choking in geriatric and nursing home patients

    NARCIS (Netherlands)

    Poelgeest, A. van; Melis, R.J.F.; Ritmeijer, C.; Olde Rikkert, M.G.M.

    2006-01-01

    It is unknown how often choking occurs in geriatric wards and in nursing homes and what the treatment and outcomes are in regular practice. A questionnaire was sent to Dutch geriatricians (N = 130), nursing home physicians (N = 130), and trainees for these disciplines (N = 215), in order to gain inf

  12. Spontaneous rupture of incisional hernia: A rare life-threatening complication of incisional hernia

    OpenAIRE

    2013-01-01

    An incisional hernia develops in the scar of a surgical incision. Spontaneous rupture of an abdominal hernia is very rare and usually occurs in incisional or recurrent groin hernia. This is a report of 50-year-old female who presented with sudden spontaneous rupture of an incisional hernia. This hernia was repaired by mesh repair after repositioning the bowel into the peritoneal cavity and excising the excess atrophied skin. The patient recovered well and was discharge after the 4th day. Spon...

  13. A Rare Cause of Chronic Life Threatening Bleeding in a Girl: The Ulcerated Blind Loops

    Directory of Open Access Journals (Sweden)

    Abhijeet D Sawant

    2016-04-01

    Full Text Available Ulceration in a blind loop can lead to massive gastrointestinal tract (GIT bleeding. A 13-year old girl presented with symptomatic melena requiring repeated blood transfusion since childhood. She was an operated case of small bowel atresia in neonatal life. Her upper and lower gastrointestinal endoscopies were normal. Operation showed presence of multiple ulcers in two blind loops (parts of previous side to side anastomosis and at the anastomotic site. She underwent resection and end-to-end anastomosis of the small bowel leading to complete resolution of melena and anemia.

  14. Sotalol: A rescue drug in the face of life-threatening refractory ventricular tachycardia

    Directory of Open Access Journals (Sweden)

    Ashok Kandasamy

    2014-01-01

    Full Text Available We describe postoperative refractory ventricular tachycardia (VT in a patient following aortic and mitral valve replacement. Following an uneventful separation from cardiopulmonary bypass with dobutamine, the patient developed recurrent VT, 4 hours into the postoperative period. The VT did not respond to standard doses of xylocard, magnesium and amiodarone. Electrolyte and acid base parameters were normal. Multiple cardioversions failed to revert back to a stable rhythm. Intra-aortic balloon pumping was instituted and overdrive right ventricular pacing was unsuccessful. Following intravenous sotalol 80 mg, the VT came under control and reverted to a nodal rhythm, which required atrial pacing for the next 8 hours. Oral sotalol therapy was continued at 40 mg daily. The VT did not recur.

  15. Unusual case of life threatening subcutaneous hemorrhage in a blunt trauma patient

    Directory of Open Access Journals (Sweden)

    Ashraf F. Hefny

    2015-01-01

    Conclusion: Bleeding into the subcutaneous plane in closed degloving injury can cause severe hypovolemic shock. It is important for the clinicians managing trauma patients to be aware this serious injury.

  16. Autoethnography: reflective journaling and meditation to cope with life-threatening breast cancer.

    Science.gov (United States)

    Sealy, Patricia Ann

    2012-02-01

    Autoethnography is a qualitative research approach whereby the researcher shares personal stories that relate to the broader cultural context. Living through breast cancer showed me how reflective journaling and meditation can help one to cope with locally advanced breast cancer. The purpose of this autoethnography is to assist nurses in gaining a greater understanding of the primary cultural implications of (a) unresolved emotional issues from the past complicating current treatment and recovery for locally advanced breast cancer, and that (b) reflective journaling and meditation can provide an opportunity to "socially reconstruct" past psychological injury. In this example of autoethnography, I reconstructed the past by re-experiencing childhood wounds through meditation, accompanied by myself in the role of the nurturing mother providing comfort and support to the wounded inner child. That approach affirmed me in my current mothering role and provided imagery of the comfort that I was lacking in my childhood. Such duality empowered me toward self-acceptance and self-worth. Loss, grief, fear, and anxiety are considered universal states and emotions that interfere with quality of life. Finding meaning in suffering can heal pain and free energy for the pursuit of justice, peace, and joy. PMID:22297005

  17. Emphysematous pyelonephritis: A rare life-threatening complication after extracorporeal shock wave lithotripsy

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Su Ho; Chung, Dong Jin; Yeo, Dong Myung; Sonh, Dong Wan; Hahn, Sung Tae [Yeouido St. Mary' s Hospital, College of Medicine, The Catholic University of Korea, Seoul (Korea, Republic of)

    2015-09-15

    Emphysematous pyelonephritis (EPN), caused by extracorporeal shock wave lithotripsy (ESWL), has not been reported in the literature; and the mechanism of this disease is unknown. Although many studies have conjectured about the various causes of EPN, ESWL was not one of them. The patient in this report was a 65-year-old woman with a past medical history of diabetes; the patient underwent an ESWL that caused the EPN. To the best of our knowledge, this is the first report of an EPN case that was caused by ESWL.

  18. Life-Threatening Simultaneous Bilateral Spontaneous Tension Pneumothorax - A case report -

    OpenAIRE

    Rim, Taegeun; Bae, Joo Suck; Yuk, Yong Soo

    2011-01-01

    Spontaneous pneumothorax is a common clinical problem in emergency care. However, the overall incidences of primary spontaneous pneumothorax has been reported from as low as 1.4% to 7.6%. The clinical findings of simultaneous bilateral spontaneous pneumothorax can be variable. Clinical presentation is variable, ranging from mild dyspnea to tension pneumothorax. Bilateral tension pneumothorax can defined as cases where no tracheal deviation is detected in chest X-ray, and symptoms may be equal...

  19. Development of an Educational Packet for Persons with Life-Threatening Food Allergies

    Science.gov (United States)

    Olson, Bradley F.; Teuber, Suzanne; Bruhn, Christine M.

    2009-01-01

    Previous studies have shown that those with severe food allergies have significant gaps in knowledge about their disease and how to prevent recurrences. The purpose of this study was to address these deficiencies by creating and testing an educational packet, "Coping with Food Allergies." Participants included 46 of 58 adults with documented…

  20. Sotalol: a rescue drug in the face of life-threatening refractory ventricular tachycardia.

    Science.gov (United States)

    Kandasamy, Ashok; Arumugham, Sukumar; Krupanandha, Harshavardhan; Reddy, Bhaktavatsala

    2014-01-01

    We describe postoperative refractory ventricular tachycardia (VT) in a patient following aortic and mitral valve replacement. Following an uneventful separation from cardiopulmonary bypass with dobutamine, the patient developed recurrent VT, 4 hours into the postoperative period. The VT did not respond to standard doses of xylocard, magnesium and amiodarone. Electrolyte and acid base parameters were normal. Multiple cardioversions failed to revert back to a stable rhythm. Intra-aortic balloon pumping was instituted and overdrive right ventricular pacing was unsuccessful. Following intravenous sotalol 80 mg, the VT came under control and reverted to a nodal rhythm, which required atrial pacing for the next 8 hours. Oral sotalol therapy was continued at 40 mg daily. The VT did not recur. PMID:24732625

  1. Wing pathology of white-nose syndrome in bats suggests life-threatening disruption of physiology

    Science.gov (United States)

    Cryan, P.M.; Meteyer, C.U.; Boyles, J.G.; Blehert, D.S.

    2010-01-01

    White-nose syndrome (WNS) is causing unprecedented declines in several species of North American bats. The characteristic lesions of WNS are caused by the fungus Geomyces destructans, which erodes and replaces the living skin of bats while they hibernate. It is unknown how this infection kills the bats. We review here the unique physiological importance of wings to hibernating bats in relation to the damage caused by G. destructans and propose that mortality is caused by catastrophic disruption of wing-dependent physiological functions. Mechanisms of disease associated with G. destructans seem specific to hibernating bats and are most analogous to disease caused by chytrid fungus in amphibians. ?? 2010 Cryan et al; licensee BioMed Central Ltd.

  2. Life-threatening interaction between the root extract of Pueraria lobata and methotrexate in rats

    International Nuclear Information System (INIS)

    Isoflavone supplements are nowadays widely used as alternative for hormone replacement therapy. However, the safety remains unanswered. This study attempted to investigate the effect of Pueraria lobata root decoction (PLRD), an isoflavone-rich herb, on the pharmacokinetics of methotrexate (MTX), a bicarboxylate antimetabolite with narrow therapeutic window. Rats were orally and intravenously given methotrexate alone and coadministered with PLRD. Blood samples were withdrawn via cardiopuncture at specific time points after drug administration. Serum methotrexate concentrations were assayed by specific monoclonal fluorescence polarization immunoassay method. Pharmacokinetic parameters were calculated using noncompartment model of WINNONLIN for both oral and intravenous data of MTX. Our results showed that coadministration of 4.0 g/kg and 2.0 g/kg of PLRD significantly increased the AUC0-t by 207.8% and 127.9%, prolonged the mean residence time (MRT) by 237.8 and 155.2%, respectively, finally resulted in surprisingly high mortalities of 57.1% and 14.3% in rats. When MTX was given intravenously, the coadministration of PLRD at 4.0 g/kg significantly increased the half-life by 53.9% and decreased the clearance by 47.9%. In conclusion, the coadministration of PLRD significantly decreased the elimination and resulted in markedly increased exposure of MTX in rats

  3. Penetrated sigmoid colon by air gun pellet could be life threatening: A case report

    OpenAIRE

    Krasniqi, Avdyl S; Hamza, Astrit R; Valon A. Zejnullahu; Fatos E. Sada; Besnik X. Bicaj

    2014-01-01

    INTRODUCTION: Air and paintball guns have been in existence for over 400 year. Although serious injury or death can result from the use of such guns, previous literature has not mentioned the issue of the penetration of the sigmoid colon by an air gun pellet. PRESENTATION OF CASE: We report a rare case of a 44-year-old Caucasian woman referred to abdominal surgery after an accidental small wound had occurred in the lower left abdominal quadrant that was caused by an air gun pellet. The blo...

  4. Penetrated sigmoid colon by air gun pellet could be life threatening: A case report

    Science.gov (United States)

    Krasniqi, Avdyl S.; Hamza, Astrit R.; Zejnullahu, Valon A.; Sada, Fatos E.; Bicaj, Besnik X.

    2014-01-01

    INTRODUCTION Air and paintball guns have been in existence for over 400 year. Although serious injury or death can result from the use of such guns, previous literature has not mentioned the issue of the penetration of the sigmoid colon by an air gun pellet. PRESENTATION OF CASE We report a rare case of a 44-year-old Caucasian woman referred to abdominal surgery after an accidental small wound had occurred in the lower left abdominal quadrant that was caused by an air gun pellet. The blood and biochemical analyses were normal but the CT scan revealed the presence of a foreign body – an air gun pellet in the left iliac region of the abdomen. Clinically, during the initial 24 h significant changes were not noticed. After 42 h, however, pain and local tenderness in the lower left abdominal quadrant was expressed. A laparotomy revealed a retained pellet in the wall of the sigmoid colon and a small leak with colonic content with consecutive local peritonitis also occurred. The foreign body was removed and the opening edges in the colon were excised and closed with the primary suture. DISCUSSION The hollow organs of the digestive tract, albeit very rarely penetrated by an air gun pellet, do not typically show all signs of an acute abdomen in the early posttraumatic phase. Such injuries can lead to a pronounced infection, which may cause septic shock if not appropriately treated. CONCLUSION For correct diagnosis, a careful approach and several daily clinical observations are required. PMID:25437671

  5. Multimodality Evaluation of Intravenous Leiomyomatosis: A Rare, Benign but Potentially Life-Threatening Tumor

    Science.gov (United States)

    Fornaris, Reinaldo J.; Rivera, Melisa; Jiménez, Luis; Maldonado, José

    2015-01-01

    Patient: Female, 40 Final Diagnosis: Intravenous leiomyomatosis Symptoms: Chest pain • syncope Medication: — Clinical Procedure: Thoracotomy Specialty: Radiology • Cardiology Objective: Rare disease Background: Intravenous leiomyomatosis (IVL) is a rare tumor, which is usually of uterine origin, characterized by intravascular nodular masses of histologically benign smooth muscle that may extend variable distances, including into the inferior vena cava, right atrium and pulmonary arteries. Tumors may arise from uterine leiomyoma, walls of the uterine vessel, or myometrium. It usually occurs at between 20–70 years of age with a median age of 45 years. The most commonly affected women are pre-menopausal and multiparous. Intra-cardiac extension may represent a diagnostic challenge as it is usually misdiagnosed as a right atrial myxoma and may cause multiple symptoms, such as shortness of breath, tachycardia, chest pain, syncope, and even death. Case Report: We present the case of a 40-year-old female patient with past medical history of arterial hypertension, who was referred to a cardiovascular center due to an intra-cardiac mass found on 2D echocardiogram. The patient was given the rare diagnosis of intravenous leiomyomatosis of the uterus with extension into the gonadal veins, inferior vena cava, right atrium, right ventricle, and main pulmonary arteries. Imaging workup including trans-esophageal echocardiogram, cardiac catheterization, contrast-enhanced abdomen and pelvic CT scans, and cardiac MRI was performed for evaluation. Conclusions: Intravenous leiomyomatosis is a rare diagnosis that merits consideration in a young pre-menopausal female patient with cardiac symptoms associated with a right atrial mass. Radiologists play a vital role in the diagnosis and follow-up of patients with the diagnosis of intravenous leiomyomatosis. Differential diagnosis includes vascular thrombus as well as primary and metastatic tumors. Early detection is imperative for appropriate treatment and surgical planning. PMID:26546569

  6. Expanding Hematoma's Life-Threatening Neck and Face Emergency Management of Ballistic Injuries.

    Science.gov (United States)

    Shuker, Sabri T

    2016-07-01

    This article aims to bring attention to the morbidity and fatality of hemorrhage, how expanding hematoma and air compromise neck/face N/F injuries and present challenges. Large neck vessel ballistic injuries may lead to hemorrhage and expanding hematoma, resulting in airway compromise, due to injuries to the internal and/or external carotid arteries, internal jugular veins "internal carotid artery, external carotid artery, internal jugular vein," and the external carotid artery deep branches. This also leads to injuries to the cervical fascial layers (barriers of deep spaces) that facilitate pooling blood and hematoma into compartmental and large potential space which effects the pharynx, larynx, esophagus, and trachea.The expanding hematomas distort neck anatomical landmarks so "no neck zones" classifications are applicable. As the spectrum of injuries continues to evolve, the clinical characterization needs a new categorization based on compartmental hematoma and potential space anatomical location like retropharyngeal, parapharyngeal, sublingual, submandibular spaces, retrobulbar, and cheek compartment space hematomas.Presence of symptoms and location of the hematoma generally dictate what type of procedure is needed and how urgently it needs to be appropriately performed.Two unusual patients of pseudoaneurysms facial artery injuries with extravasation of blood producing a pulsating hematoma are referred to. Another patient considers large internal carotid artery injuries pseudoaneurysms revealed in angiography.The immediate management of life-saving patients requires aggressive airway maintenance at the scene, conscious victim will often obtain a posture that clears his airway and the semiconscious or unconscious put him in prone position. Air compromise may need emergency intubation, large bore cannula cricothyroidotomy, cricothyrotomy and at medical facilities tracheostomy. PMID:27315316

  7. Life-Threatening Cardiac Tamponade Secondary to Chylopericardium Following Orthotopic Heart Transplantation-A Case Report.

    Science.gov (United States)

    Wierzbicki, Karol; Mazur, Piotr; Węgrzyn, Piotr; Kapelak, Bogusław

    2016-08-23

    Chylopericardium is a rare complication in cardiac surgery, and an extremely rare occurrence in patients following orthotopic heart transplantation (OHT), which, however, can lead to cardiac tamponade. Here we present a case of a 59-year-old man who underwent OHT and suffered from chylopericardium resulting in cardiac tamponade late in the postoperative course, despite the initially uneventful early postoperative period (decreasing blood drainage was observed directly after the procedure, and the drains were safely removed). After the diagnosis of chylopericardium was made, the conservative treatment was initiated, which turned out to be insufficient, and eventually invasive approach for the recurrence of tamponade secondary to chylopericardium was required. We discuss the available therapeutic options for chylopericardium and demonstrate the successful invasive therapeutic approach with use of the absorbable fibrin sealant patch. PMID:26548537

  8. Autoethnography: reflective journaling and meditation to cope with life-threatening breast cancer.

    Science.gov (United States)

    Sealy, Patricia Ann

    2012-02-01

    Autoethnography is a qualitative research approach whereby the researcher shares personal stories that relate to the broader cultural context. Living through breast cancer showed me how reflective journaling and meditation can help one to cope with locally advanced breast cancer. The purpose of this autoethnography is to assist nurses in gaining a greater understanding of the primary cultural implications of (a) unresolved emotional issues from the past complicating current treatment and recovery for locally advanced breast cancer, and that (b) reflective journaling and meditation can provide an opportunity to "socially reconstruct" past psychological injury. In this example of autoethnography, I reconstructed the past by re-experiencing childhood wounds through meditation, accompanied by myself in the role of the nurturing mother providing comfort and support to the wounded inner child. That approach affirmed me in my current mothering role and provided imagery of the comfort that I was lacking in my childhood. Such duality empowered me toward self-acceptance and self-worth. Loss, grief, fear, and anxiety are considered universal states and emotions that interfere with quality of life. Finding meaning in suffering can heal pain and free energy for the pursuit of justice, peace, and joy.

  9. Ionic liquids as unforeseen assets to fight life-threatening mycotic diseases

    OpenAIRE

    Hartmann, Diego O; Marija ePetkovic; Cristina eSilva Pereira

    2016-01-01

    Ionic liquids discovery has celebrated 100 years. They consist solely of ions, one of which is typically organic and asymmetrical. Remarkable physical and chemical properties stirred their use as alternative solvents in many chemical processes. The recent demonstration of their occurrence in nature might boost their interest in biological sciences. In the search of mechanistic understandings of ionic liquids’ ecotoxicological impacts in fungi, we have analyzed the proteome, transcriptome and ...

  10. Intrathecal baclofen withdrawal syndrome- a life-threatening complication of baclofen pump: A case report

    OpenAIRE

    Mohammed, Imran; Hussain, Asif

    2004-01-01

    Background Intrathecal baclofen pump has been used effectively with increasing frequency in patients with severe spasticity, particularly for those patients who are unresponsive to conservative pharmacotherapy or develop intolerable side effects at therapeutic doses of oral baclofen. Drowsiness, nausea, headache, muscle weakness, light-headedness and return of pretreatment spasticity can be caused by intrathecal pump delivering an incorrect dose of baclofen. Intrathecal baclofen withdrawal sy...

  11. Life-threatening ketoacidosis in a pregnant woman with psychotic disorder.

    Science.gov (United States)

    Frise, Charlotte; Attwood, Ben; Watkinson, Peter; Mackillop, Lucy

    2016-03-01

    Pregnancy is an insulin resistant state. Hyperglycaemia and gestational diabetes mellitus are well-recognised complications even in women without existing metabolic syndrome or obesity. Pregnant women also appear to be more vulnerable to ketoacidosis, particularly after short periods of reduced oral intake in the third trimester, and may present with very severe starvation ketoacidosis, prompting emergent delivery. We present a case of a woman with a background of depression and psychotic episodes. Olanzapine had been commenced after a psychotic episode at 20 weeks' gestation. Gestational diabetes mellitus was diagnosed at 28 weeks, and she was then admitted at 31 weeks with severe euglycaemic ketoacidosis following a short period of vomiting. She underwent caesarean section when the metabolic disturbances did not resolve with medical treatment. We believe atypical antipsychotic therapy contributed to the profound insulin resistance seen here, and that obstetricians, physicians and psychiatrists must be aware of the risks conferred by these agents in pregnancy. PMID:27512491

  12. Non-Life Threatening Maternal Morbidity: Cross Sectional Surveys from Malawi and Pakistan.

    Directory of Open Access Journals (Sweden)

    Shamsa Zafar

    Full Text Available For more accurate estimation of the global burden of pregnancy associated disease, clarity is needed on definition and assessment of non-severe maternal morbidity. Our study aimed to define maternal morbidity with clear criteria for identification at primary care level and estimate the distribution of and evaluate associations between physical (infective and non-infective and psychological morbidities in two different low-income countries.Cross sectional study with assessment of morbidity in early pregnancy (34%, late pregnancy (35% and the postnatal period (31% among 3459 women from two rural communities in Pakistan (1727 and Malawi (1732. Trained health care providers at primary care level used semi-structured questionnaires documenting signs and symptoms, clinical examination and laboratory tests which were bundled to reflect infectious, non-infectious and psychological morbidity.One in 10 women in Malawi and 1 in 5 in Pakistan reported a previous pregnancy complication with 1 in 10 overall reporting a previous neonatal death or stillbirth. In the index pregnancy, 50.1% of women in Malawi and 53% in Pakistan were assessed to have at least one morbidity (infective or non-infective. Both infective (Pakistan and non-infective morbidity (Pakistan and Malawi was lower in the postnatal period than during pregnancy. Multiple morbidities were uncommon ( 9. Complications during a previous pregnancy, infective morbidity (p <0.001, intra or postpartum haemorrhage (p <0.02 were associated with psychological morbidity in both settings.Our findings highlight the need to strengthen the availability and quality of antenatal and postnatal care packages. We propose to adapt and improve the framework and criteria used in this study, ensuring a basic set of diagnostic tests is available, to ensure more robust assessment of non-severe maternal morbidity.

  13. Peritoneal adhesion: it can be life-threatening, and life-saving

    Directory of Open Access Journals (Sweden)

    Huang Jiun-Chi

    2012-09-01

    Full Text Available Abstract Background The inevitable post-inflammatory fibrosis and adhesion often compromises future treatment in peritoneal dialysis patients. Here, we describe a patient who experienced an unusual form of peritoneal adhesion that made her give up peritoneal dialysis. However, its unique pattern also saved her from infection caused by bowel perforation. Case presentation The female patient discontinued peritoneal dialysis due to gradual dialysis inadequacy. Two months after shifting to hemodialysis with generally improved sense of well-being and no sign of abdominal illness, she was admitted to remove the Tenckhoff catheter. The procedure was smooth, but fever and abdominal pain not at the site of operation developed the next day. Abdominal ultrasound showed the presence of ascites and aspiration revealed slimy, green-yellowish pus that gave a negative result on bacterial culture. Abdominal computed tomography (CT with oral contrast medium was performed, but failed to demonstrate the suspected bowel perforation. The examination, however, did show accumulation of pus inside the abdomen but outside the peritoneal cavity. We drained the pus with two 14-F Pig-tail catheters and the total amount of drainage approached 4000 ml. The second CT was performed with double dose of the contrast medium and found a leak of the contrast from the jejunum. She then received laparotomy and had the perforation site closed. Conclusions In summary, this uremic patient suffered from pus accumulation inside her abdomen without obvious systemic toxic effect. The bowel perforation and pus formation might be caused by repeated peritonitis, but the peritoneal adhesion itself might also isolate her peritoneal cavity from the anticipated toxic injuries of bowel perforation.

  14. Wing pathology of white-nose syndrome in bats suggests life-threatening disruption of physiology

    Science.gov (United States)

    Cryan, Paul M.; Meteyer, Carol U.; Boyles, Justin G.; Blehert, David S.

    2010-01-01

    White-nose syndrome (WNS) is causing unprecedented declines in several species of North American bats. The characteristic lesions of WNS are caused by the fungus Geomyces destructans, which erodes and replaces the living skin of bats while they hibernate. It is unknown how this infection kills the bats. We review here the unique physiological importance of wings to hibernating bats in relation to the damage caused by G. destructans and propose that mortality is caused by catastrophic disruption of wing-dependent physiological functions. Mechanisms of disease associated with G. destructans seem specific to hibernating bats and are most analogous to disease caused by chytrid fungus in amphibians.

  15. Late onset ipilimumab-induced pericarditis and pericardial effusion: a rare but life threatening complication.

    Science.gov (United States)

    Yun, Seongseok; Vincelette, Nicole D; Mansour, Iyad; Hariri, Dana; Motamed, Sara

    2015-01-01

    Metastatic cutaneous melanoma has poor prognosis with 2-year survival rate of 10-20%. Melanoma cells express various antigens including gp100, melanoma antigen recognized by T cells 1 (MART-1), and tyrosinase, which can induce immune-mediated anticancer response via T cell activation. Cytotoxic T-lymphocyte associated antigen-4 (CTLA-4) is an immune check point molecule that negatively regulates T cell activation and proliferation. Accordingly, recent phase III clinical trials demonstrated significant survival benefit with ipilimumab, a human monoclonal antibody (IgG1) that blocks the interaction of CTLA-4 with its ligands. Since the efficacy of ipilimumab depends on T cell activation, it is associated with substantial risk of immune mediated adverse reactions such as colitis, hepatitis, thyroiditis, and hypophysitis. We report the first case of late onset pericarditis and cardiac tamponade associated with ipilimumab treatment in patient with metastatic cutaneous melanoma. PMID:25918658

  16. Late Onset Ipilimumab-Induced Pericarditis and Pericardial Effusion: A Rare but Life Threatening Complication

    Directory of Open Access Journals (Sweden)

    Seongseok Yun

    2015-01-01

    Full Text Available Metastatic cutaneous melanoma has poor prognosis with 2-year survival rate of 10–20%. Melanoma cells express various antigens including gp100, melanoma antigen recognized by T cells 1 (MART-1, and tyrosinase, which can induce immune-mediated anticancer response via T cell activation. Cytotoxic T-lymphocyte associated antigen-4 (CTLA-4 is an immune check point molecule that negatively regulates T cell activation and proliferation. Accordingly, recent phase III clinical trials demonstrated significant survival benefit with ipilimumab, a human monoclonal antibody (IgG1 that blocks the interaction of CTLA-4 with its ligands. Since the efficacy of ipilimumab depends on T cell activation, it is associated with substantial risk of immune mediated adverse reactions such as colitis, hepatitis, thyroiditis, and hypophysitis. We report the first case of late onset pericarditis and cardiac tamponade associated with ipilimumab treatment in patient with metastatic cutaneous melanoma.

  17. Life-threatening hyperkalemia in a patient with normal renal function

    OpenAIRE

    Ayach, Taha; Nappo, Robert W.; Paugh-Miller, Jennifer L.; Ross, Edward A.

    2013-01-01

    With media focus on benefits from reducing sodium intake, there is increased popularity of salt substitutes, typically potassium chloride. While viewed by the public as a healthy alternative to standard table salt, less appreciated is the severe risk with certain comorbidities and medications. We report the case of an elderly female with chronically high salt substitute intake, normal renal function, diabetes, hypertension treated with angiotensin-converting enzyme inhibitor and beta blockade...

  18. Sexuality and Life-Threatening Illness: Implications for Social Work and Palliative Care

    Science.gov (United States)

    Cagle, John G.; Bolte, Sage

    2009-01-01

    Social workers in hospice and palliative care settings have been charged with the responsibility of addressing sexuality with their patients and families. However, little direction has been offered as to how to approach this difficult subject within the context of palliative care. This article provides a critical analysis of the previous…

  19. Ionic Liquids as Unforeseen Assets to Fight Life-Threatening Mycotic Diseases.

    Science.gov (United States)

    Hartmann, Diego O; Petkovic, Marija; Silva Pereira, Cristina

    2016-01-01

    Ionic liquids discovery has celebrated 100 years. They consist solely of ions, one of which is typically organic and asymmetrical. Remarkable physical and chemical properties stirred their use as alternative solvents in many chemical processes. The recent demonstration of their occurrence in nature might boost their interest in biological sciences. In the search of mechanistic understandings of ionic liquids' ecotoxicological impacts in fungi, we have analyzed the proteome, transcriptome, and metabolome responses to this chemical stress. Data illuminated new hypotheses that altered our research path - exploit ionic liquids as tools for the discovery of pathways and metabolites that may impact fungal development and pathogenicity. As we get closer to solve the primary effects of each ionic liquid family and their specific gene targets, the vision of developing antifungal ionic liquids and/or materials, by taking advantage of elegant progresses in this field, might become a reality. Task-designed formulations may improve the performance of conventional antifungal drugs, build functional coatings for reducing allergens production, or aid in the recovery of antifungal plant polymers. The frontier research in this cross-disciplinary field may provide us unforeseen means to address the global concern of mycotic diseases. Pathogenic and opportunistic fungi are responsible for numerous infections, killing annually nearly 1.5 million immunocompromised individuals worldwide, a similar rate to malaria or tuberculosis. This perspective will review our major findings and current hypotheses, contextualizing how they might bring us closer to efficient strategies to prevent and fight mycotic diseases.

  20. [Life threatening postpartal haemorrhage after rupture of the vagina, uterine cervix, caesarean section or hysterectomy].

    Science.gov (United States)

    Kozovski, I; Radoinova, D

    2010-01-01

    The authors discuss 10 cases--seven after vaginal and cervical rupture, 2 after Caesarean section and 1 after hysterectomy. Six of them died--5 after rupture of the vagina and cervix and one after Caesarean section. The lethal issue was avoidable in all cases because it was a result of untimely done or not done at all hysterectomy and other interventions, e.g., ligation of the hypogastric arteries, as well as of faulty surgical performance. Basic principles of surgical behavior in such cases are postulated.

  1. Life Threatening Severe QTc Prolongation in Patient with Systemic Lupus Erythematosus due to Hydroxychloroquine

    Directory of Open Access Journals (Sweden)

    John P. O’Laughlin

    2016-01-01

    Full Text Available We present a case of a syncopal episode resulting from significant QT interval prolongation in a patient on hydroxychloroquine for the treatment of systemic lupus erythematosus and end stage renal disease. The patient had been treated with hydroxychloroquine for two years prior to presentation. After thorough workup for secondary causes of QT interval prolongation hydroxychloroquine was discontinued and the patient’s QT interval shortened. The patient was treated with mexiletine to prevent sudden ventricular arrhythmias, which was unique compared to other documented cases in which lidocaine was used. The patient was noted to have mild prolongation of the QT interval on electrocardiogram prior to initiation of hydroxychloroquine therapy which was exacerbated by its use and may have been caused due to toxicity from underlying renal failure.

  2. Life Threatening Severe QTc Prolongation in Patient with Systemic Lupus Erythematosus due to Hydroxychloroquine.

    Science.gov (United States)

    O'Laughlin, John P; Mehta, Parag H; Wong, Brian C

    2016-01-01

    We present a case of a syncopal episode resulting from significant QT interval prolongation in a patient on hydroxychloroquine for the treatment of systemic lupus erythematosus and end stage renal disease. The patient had been treated with hydroxychloroquine for two years prior to presentation. After thorough workup for secondary causes of QT interval prolongation hydroxychloroquine was discontinued and the patient's QT interval shortened. The patient was treated with mexiletine to prevent sudden ventricular arrhythmias, which was unique compared to other documented cases in which lidocaine was used. The patient was noted to have mild prolongation of the QT interval on electrocardiogram prior to initiation of hydroxychloroquine therapy which was exacerbated by its use and may have been caused due to toxicity from underlying renal failure. PMID:27478650

  3. FAST: towards safe and effective subcutaneous immunotherapy of persistent life-threatening food allergies.

    Science.gov (United States)

    Zuidmeer-Jongejan, Laurian; Fernandez-Rivas, Montserrat; Poulsen, Lars K; Neubauer, Angela; Asturias, Juan; Blom, Lars; Boye, Joyce; Bindslev-Jensen, Carsten; Clausen, Michael; Ferrara, Rosa; Garosi, Paula; Huber, Hans; Jensen, Bettina M; Koppelman, Stef; Kowalski, Marek L; Lewandowska-Polak, Anna; Linhart, Birgit; Maillere, Bernard; Mari, Adriano; Martinez, Alberto; Mills, Clare En; Nicoletti, Claudio; Opstelten, Dirk-Jan; Papadopoulos, Nikos G; Portoles, Antonio; Rigby, Neil; Scala, Enrico; Schnoor, Heidi J; Sigurdardottir, Sigurveig T; Stavroulakis, George; Stolz, Frank; Swoboda, Ines; Valenta, Rudolf; van den Hout, Rob; Versteeg, Serge A; Witten, Marianne; van Ree, Ronald

    2012-03-09

    The FAST project (Food Allergy Specific Immunotherapy) aims at the development of safe and effective treatment of food allergies, targeting prevalent, persistent and severe allergy to fish and peach. Classical allergen-specific immunotherapy (SIT), using subcutaneous injections with aqueous food extracts may be effective but has proven to be accompanied by too many anaphylactic side-effects. FAST aims to develop a safe alternative by replacing food extracts with hypoallergenic recombinant major allergens as the active ingredients of SIT. Both severe fish and peach allergy are caused by a single major allergen, parvalbumin (Cyp c 1) and lipid transfer protein (Pru p 3), respectively. Two approaches are being evaluated for achieving hypoallergenicity, i.e. site-directed mutagenesis and chemical modification. The most promising hypoallergens will be produced under GMP conditions. After pre-clinical testing (toxicology testing and efficacy in mouse models), SCIT with alum-absorbed hypoallergens will be evaluated in phase I/IIa and IIb randomized double-blind placebo-controlled (DBPC) clinical trials, with the DBPC food challenge as primary read-out. To understand the underlying immune mechanisms in depth serological and cellular immune analyses will be performed, allowing identification of novel biomarkers for monitoring treatment efficacy. FAST aims at improving the quality of life of food allergic patients by providing a safe and effective treatment that will significantly lower their threshold for fish or peach intake, thereby decreasing their anxiety and dependence on rescue medication.

  4. FAST: towards safe and effective subcutaneous immunotherapy of persistent life-threatening food allergies

    Directory of Open Access Journals (Sweden)

    Zuidmeer-Jongejan Laurian

    2012-03-01

    Full Text Available Abstract The FAST project (Food Allergy Specific Immunotherapy aims at the development of safe and effective treatment of food allergies, targeting prevalent, persistent and severe allergy to fish and peach. Classical allergen-specific immunotherapy (SIT, using subcutaneous injections with aqueous food extracts may be effective but has proven to be accompanied by too many anaphylactic side-effects. FAST aims to develop a safe alternative by replacing food extracts with hypoallergenic recombinant major allergens as the active ingredients of SIT. Both severe fish and peach allergy are caused by a single major allergen, parvalbumin (Cyp c 1 and lipid transfer protein (Pru p 3, respectively. Two approaches are being evaluated for achieving hypoallergenicity, i.e. site-directed mutagenesis and chemical modification. The most promising hypoallergens will be produced under GMP conditions. After pre-clinical testing (toxicology testing and efficacy in mouse models, SCIT with alum-absorbed hypoallergens will be evaluated in phase I/IIa and IIb randomized double-blind placebo-controlled (DBPC clinical trials, with the DBPC food challenge as primary read-out. To understand the underlying immune mechanisms in depth serological and cellular immune analyses will be performed, allowing identification of novel biomarkers for monitoring treatment efficacy. FAST aims at improving the quality of life of food allergic patients by providing a safe and effective treatment that will significantly lower their threshold for fish or peach intake, thereby decreasing their anxiety and dependence on rescue medication.

  5. Common adder bite to the tongue causing life threatening toxicity from airway compromise

    DEFF Research Database (Denmark)

    Hoegberg, Lotte C G; Jessen, Casper L; Lambertsen, Karin;

    2010-01-01

    We illustrate the acute phase and development of symptoms in a 24-year-old man following a European Common Viper bite to the tongue.......We illustrate the acute phase and development of symptoms in a 24-year-old man following a European Common Viper bite to the tongue....

  6. Life-threatening posterior fossa cyst induced by pseudomeningocele after operation for acoustic neuroma

    Directory of Open Access Journals (Sweden)

    Jung-Ying Chiang

    2015-01-01

    Conclusion: We discuss the clinical features, possible pathophysiological mechanisms, and treatment options for pseudomeningocele. Although most cases of pseudomeningocele follow a benign course and need only conservative treatment, the potential attendant complications, such as an enlarged cyst, may still have fatal consequences. We believe that it is beneficial to take an aggressive attitude toward this condition and to consider the possibility of surgical interventions more seriously.

  7. Life-threatening hemorrhage from acquired hemophilia A as a presenting manifestation of prostate cancer

    Science.gov (United States)

    Sheth, Chirag; Gill, Amandeep; Sekhon, Sumeet

    2016-01-01

    Acquired factor VIII deficiency (acquired hemophilia A) is a rare condition characterized by the acquisition of autoantibodies that affect the clotting activity of factor VIII (fVIII). The most common manifestation in affected patients is a hemorrhagic diathesis. This disorder is associated with autoimmune diseases, pregnancy, postpartum period, drugs, and malignancy. Management of this condition begins with attempts to arrest an acute bleed based on the site and severity of bleeding and inhibitor titer. The next priority is eradication of the fVIII antibodies using immunosuppressive therapies. We report the case of a 66-year-old male who presented with spontaneous right thigh hematoma with prolonged activated partial prothrombin time and normal prothrombin time. Mixing studies confirmed the presence of an inhibitor. Further investigation for the underlying etiology of acquired hemophilia A leads to diagnosis of prostate cancer. Treatment consisted of bypassing agents including activated factor VII and activated prothrombin plasma concentrate to arrest the bleeding. Steroids and cyclophosphamide were added to suppress the fVIII inhibitors. Concomitant treatment of locally advanced prostate cancer with chemotherapy confirmed the eradication of the inhibitors. To our knowledge, this is the first reported case of prostate cancer diagnosed and treated simultaneously with acquired hemophilia A resulting in favorable patient outcome. PMID:27609734

  8. Life-threatening hemorrhage from acquired hemophilia A as a presenting manifestation of prostate cancer

    Directory of Open Access Journals (Sweden)

    Chirag Sheth

    2016-09-01

    Full Text Available Acquired factor VIII deficiency (acquired hemophilia A is a rare condition characterized by the acquisition of autoantibodies that affect the clotting activity of factor VIII (fVIII. The most common manifestation in affected patients is a hemorrhagic diathesis. This disorder is associated with autoimmune diseases, pregnancy, postpartum period, drugs, and malignancy. Management of this condition begins with attempts to arrest an acute bleed based on the site and severity of bleeding and inhibitor titer. The next priority is eradication of the fVIII antibodies using immunosuppressive therapies. We report the case of a 66-year-old male who presented with spontaneous right thigh hematoma with prolonged activated partial prothrombin time and normal prothrombin time. Mixing studies confirmed the presence of an inhibitor. Further investigation for the underlying etiology of acquired hemophilia A leads to diagnosis of prostate cancer. Treatment consisted of bypassing agents including activated factor VII and activated prothrombin plasma concentrate to arrest the bleeding. Steroids and cyclophosphamide were added to suppress the fVIII inhibitors. Concomitant treatment of locally advanced prostate cancer with chemotherapy confirmed the eradication of the inhibitors. To our knowledge, this is the first reported case of prostate cancer diagnosed and treated simultaneously with acquired hemophilia A resulting in favorable patient outcome.

  9. Successful reversal of life threatening cardiac effect following dosulepin overdose using intravenous lipid emulsion

    DEFF Research Database (Denmark)

    Boegevig, Soeren; Rothe, Anders; Tfelt-Hansen, Jacob;

    2011-01-01

    . On submission the QRS complex was 120 ms and the QT interval was 348 ms (BP 129/71 mmHg, HR 113 beats/min). Her level of consciousness deteriorated and the patient had episodes of seizures. The patient received bicarbonate, 200 mmol, and assisted ventilation. Ninety minutes following submission, the QRS complex...... was 158 ms and the QT interval was 422 ms (BP 118/55 mmHg, HR 91 beats/min), and to treat the intoxication intravenous lipid emulsion 20% was dosed as 1.5 ml/kg (100 ml) in 5 min followed by 400 ml in 20 min. Blood pressure was immediately stabilised and the monitored QRS complex narrowed and QT interval...... and supported ventilation. However, the effects of the treatment of the severe dosulepin intoxication support the theory of intravenous lipid emulsions creating an intravenous lipid sink for drugs with high lipid solubility....

  10. [Very rare and life-threatening complications of bocavirus bronchiolitis: pneumomediastinum and bilateral pneumothorax].

    Science.gov (United States)

    Yeşilbaş, Osman; Kıhtır, Hasan Serdar; Talip Petmezci, Mey; Balkaya, Seda; Hatipoğlu, Nevin; Meşe, Sevim; Şevketoğlu, Esra

    2016-01-01

    Human bocavirus (HBoV), that was first identified in 2005 and classified in Parvoviridae family, is a small, non-enveloped, single-stranded DNA virus, responsible for upper and lower respiratory tract infections, especially in young children. Although HBoV generally causes self-limited influenza-like illness, it may also lead to pneumonia, bronchiolitis, croup and asthma attacks. In this report, a case of acute bronchiolitis complicated with pneumomediastinum and bilateral pneumothorax caused by HBoV has been presented. A three-year-old boy was referred to our pediatric intensive care unit with a two day history of fever, tachypnea, hypoxia and respiratory failure. On auscultation, there were widespread expiratory wheezing and inspiratory crackles. The chest radiography yielded paracardiac infiltration and air trapping on the right lung and infiltration on the left lung. The patient had leukocytosis and elevated C-reactive protein level. On the second day of admission, respiratory distress worsened and chest radiography revealed right pneumothorax and subcutaneous emphysema in bilateral cervical region and left chest wall. He was intubated because of respiratory failure. In the thorax computed tomography, pneumomediastinum and bilateral pneumothorax were detected and right chest tube was inserted. Repetitive blood and tracheal aspirate cultures were negative. A nasopharyngeal swab sample was analyzed by multiplex real-time polymerase chain reaction method with the use of viral respiratory panel (FTD(®) Respiratory Pathogens 21 Kit, Fast-Track Diagnostics), and positive result was detected for only HBoV. On the ninth day of admission, pneumomediastinum and bilateral pneumothorax improved completely and he was discharged with cure. In conclusion, HBoV bronchiolitis may progress rare but severe complications, it should be kept in mind as an etiological agent of the respiratory tract infections especially children younger than five years old.

  11. A case of traumatic intracranial vertebral artery injury presenting with life-threatening symptoms

    Directory of Open Access Journals (Sweden)

    Kishi S

    2012-04-01

    Full Text Available Seiji Kishi1, Kenji Kanaji2, Toshio Doi1, Tadashi Matsumura21Department of Nephrology, Tokushima University Hospital, Kuramoto-cho Tokushima, 2Department of General Internal Medicine, Rakuwakai Otowa Hospital, Otowachinji-cho Yamashina-ku Kyoto, JapanAbstract: Traumatic intracranial vertebral artery injury is a relatively rare but potentially fatal disease. We present a case of a 63-year-old man who presented with sudden onset of loss of consciousness after hitting his head. After immediate resuscitation, he showed quadriplegia and absence of spontaneous breathing. Brain and cervical spine magnetic resonance imaging revealed an atlantoaxial subluxation, fractured C2 odontoid process, left vertebral artery occlusion, and bilateral extensive ischemia in the medulla oblongata and high cervical spinal cord. Digital subtraction angiography demonstrated left vertebral artery dissection just below the level of vertebral body C2.Keywords: vertebral artery dissection, brainstem infarction, bilateral spinal cord infarction, neck trauma

  12. An unusual case of pleural-based tumor with life-threatening post-operative complication

    Directory of Open Access Journals (Sweden)

    Manoj K Goel

    2012-01-01

    Full Text Available A 57-year-old male presented with hemoptysis of 4 years duration and a gradually increasing pleural mass on chest X-ray. The mass was causing pressure effects on the liver and the lungs. To rule out malignancy, thoracotomy was performed, which revealed large, thick-walled hematoma. Complete excision of mass was performed. Post-operative course was complicated by massive pleural bleeding requiring massive blood transfusions and re-exploratory thoracotomy. Subsequent tests revealed factor IX deficiency and, hence, he was managed with recombinant factor IX concentrate. This case stresses upon the fact that hereditary bleeding disorders may be diagnosed even in late adulthood with atypical presentations such as pseudotumor in pleural space. Moreover, hemophilia B may present with normal APTT levels making the diagnosis even more difficult.

  13. Real causes of apparent abnormal results in heavy ion reactions

    Directory of Open Access Journals (Sweden)

    Mandaglio G.

    2015-01-01

    Full Text Available We study the effect of the static characteristics of nuclei and dynamics of the nucleus-nucleus interaction in the capture stage of reaction, in the competition between quasifission and complete fusion processes, as well as the angular momentum dependence of the competition between fission and evaporation processes along the de-excitation cascade of the compound nucleus. The results calculated for the mass-asymmetric and less mass-asymmetric reactions in the entrance channel are analyzed in order to investigate the role of the dynamical effects on the yields of the evaporation residue nuclei. We also discuss about uncertainties at the extraction of such relevant physical quantities as Γn/Γtot ratio or also excitation functions from the experimental results due to the not always realistic assumptions in the treatment and analysis of the detected events. This procedure can lead to large ambiguity when the complete fusion process is strongly hindered or when the fast fission contribution is large. We emphasize that a refined multiparameter model of the reaction dynamics as well as a more detailed and checked data analysis are strongly needed in heavy-ion collisions.

  14. Keterlibatan Event Stakeholders pada Keberhasilan Event PR

    OpenAIRE

    Lidya Wati Evelina

    2013-01-01

    The objective of this article is to determine how event organizers collaborate with stakeholders including the media, particular community, sponsors, participants, venue providers, accommodation providers, carteres, legal and finance personnel, production, local trade, transportation providers, government and associations for implementation Public Relations event. This paper discusses about the things that must be done for the cooperation and the benefits of cooperation undertaken. The method...

  15. Global Seismic Event Detection Using Surface Waves: 15 Possible Antarctic Glacial Sliding Events

    Science.gov (United States)

    Chen, X.; Shearer, P. M.; Walker, K. T.; Fricker, H. A.

    2008-12-01

    To identify overlooked or anomalous seismic events not listed in standard catalogs, we have developed an algorithm to detect and locate global seismic events using intermediate-period (35-70s) surface waves. We apply our method to continuous vertical-component seismograms from the global seismic networks as archived in the IRIS UV FARM database from 1997 to 2007. We first bandpass filter the seismograms, apply automatic gain control, and compute envelope functions. We then examine 1654 target event locations defined at 5 degree intervals and stack the seismogram envelopes along the predicted Rayleigh-wave travel times. The resulting function has spatial and temporal peaks that indicate possible seismic events. We visually check these peaks using a graphical user interface to eliminate artifacts and assign an overall reliability grade (A, B or C) to the new events. We detect 78% of events in the Global Centroid Moment Tensor (CMT) catalog. However, we also find 840 new events not listed in the PDE, ISC and REB catalogs. Many of these new events were previously identified by Ekstrom (2006) using a different Rayleigh-wave detection scheme. Most of these new events are located along oceanic ridges and transform faults. Some new events can be associated with volcanic eruptions such as the 2000 Miyakejima sequence near Japan and others with apparent glacial sliding events in Greenland (Ekstrom et al., 2003). We focus our attention on 15 events detected from near the Antarctic coastline and relocate them using a cross-correlation approach. The events occur in 3 groups which are well-separated from areas of cataloged earthquake activity. We speculate that these are iceberg calving and/or glacial sliding events, and hope to test this by inverting for their source mechanisms and examining remote sensing data from their source regions.

  16. Field-scale apparent hydraulic parameterisation obtained from TDR time series and inverse modelling

    Directory of Open Access Journals (Sweden)

    U. Wollschläger

    2009-10-01

    Full Text Available Due to the large heterogeneity in the hydraulic properties of natural soils, estimation of field-scale hydraulic parameters is difficult. Past research revealed that data from accurate but small-scale laboratory measurements could hardly ever be transferred to the field scale. In this study, we explore an alternative approach where apparent hydraulic properties of a layered soil profile are directly estimated from hydraulic inverse modelling of a time series of in situ measured soil water contents obtained from time domain reflectometry. The data covered a one-year period with both wet and dry soil conditions. For the time period used for inversion, the model is able to reproduce the general evolution of water content in the different soil layers reasonably well. However, distinct drying and wetting events could not be reproduced in detail which we explain by the complicated natural processes that are not fully represented in the rather simple model. The study emphasises the importance of a correct average representation of the soil-atmosphere interaction.

  17. The global event system

    Energy Technology Data Exchange (ETDEWEB)

    Winans, J.

    1994-03-02

    The support for the global event system has been designed to allow an application developer to control the APS event generator and receiver boards. This is done by the use of four new record types. These records are customized and are only supported by the device support modules for the APS event generator and receiver boards. The use of the global event system and its associated records should not be confused with the vanilla EPICS events and the associated event records. They are very different.

  18. Advertising Effectiveness In Events

    OpenAIRE

    Jain, Sushilkumar

    2012-01-01

    Confronted with decreasing effectiveness of the classic marketing communications, events have become an increasingly popular alternative for marketers. Events constitute one of the most exciting and fastest growing forms of leisure and business. With time, the decreasing effectiveness of classical marketing communications boosted the use of events for marketing and making brand awareness. Event marketing is seen as the unique opportunity to integrate the firm’s communication activities like p...

  19. Event matrix system

    International Nuclear Information System (INIS)

    The number of background events in nuclear and particle physics experiments which use multiwire proportional chambers can be extremely high. Using a computer to resolve these events results in a high deadtime for the experiment. A fast matrix system for decreasing the number of background events is described in this report. 4 figures

  20. Event generators at BESⅢ

    Institute of Scientific and Technical Information of China (English)

    PING Rong-Gang

    2008-01-01

    We present a brief remark and introduction to event generators for tau-charm physics currently used at BESⅢ,including KKMC,BesEvtGen,Bhlumi,Bhwide,Babayaga and inclusive Monte-Carlo event generators.This paper provides basic information on event generators for BESⅢ users.

  1. Serotype IV Streptococcus agalactiae ST-452 has arisen from large genomic recombination events between CC23 and the hypervirulent CC17 lineages.

    Science.gov (United States)

    Campisi, Edmondo; Rinaudo, C Daniela; Donati, Claudio; Barucco, Mara; Torricelli, Giulia; Edwards, Morven S; Baker, Carol J; Margarit, Imma; Rosini, Roberto

    2016-01-01

    Streptococcus agalactiae (Group B Streptococcus, GBS) causes life-threatening infections in newborns and adults with chronic medical conditions. Serotype IV strains are emerging both among carriers and as cause of invasive disease and recent studies revealed two main Sequence Types (STs), ST-452 and ST-459 assigned to Clonal Complexes CC23 and CC1, respectively. Whole genome sequencing of 70 type IV GBS and subsequent phylogenetic analysis elucidated the localization of type IV isolates in a SNP-based phylogenetic tree and suggested that ST-452 could have originated through genetic recombination. SNPs density analysis of the core genome confirmed that the founder strain of this lineage originated from a single large horizontal gene transfer event between CC23 and the hypervirulent CC17. Indeed, ST-452 genomes are composed by two parts that are nearly identical to corresponding regions in ST-24 (CC23) and ST-291 (CC17). Chromosome mapping of the major GBS virulence factors showed that ST-452 strains have an intermediate yet unique profile among CC23 and CC17 strains. We described unreported large recombination events, involving the cps IV operon and resulting in the expansion of serotype IV to CC23. This work sheds further light on the evolution of GBS providing new insights on the recent emergence of serotype IV. PMID:27411639

  2. Post-Marketing Surveillance of Human Rabies Diploid Cell Vaccine (Imovax) in the Vaccine Adverse Event Reporting System (VAERS) in the United States, 1990‒2015

    Science.gov (United States)

    Moro, Pedro L.; Woo, Emily Jane; Paul, Wendy; Lewis, Paige; Petersen, Brett W.; Cano, Maria

    2016-01-01

    Background In 1980, human diploid cell vaccine (HDCV, Imovax Rabies, Sanofi Pasteur), was licensed for use in the United States. Objective To assess adverse events (AEs) after HDCV reported to the US Vaccine Adverse Event Reporting System (VAERS), a spontaneous reporting surveillance system. Methods We searched VAERS for US reports after HDCV among persons vaccinated from January 1, 1990–July 31, 2015. Medical records were requested for reports classified as serious (death, hospitalization, prolonged hospitalization, disability, life-threatening-illness), and those suggesting anaphylaxis and Guillain-Barré syndrome (GBS). Physicians reviewed available information and assigned a primary clinical category to each report using MedDRA system organ classes. Empirical Bayesian (EB) data mining was used to identify disproportional AE reporting after HDCV. Results VAERS received 1,611 reports after HDCV; 93 (5.8%) were serious. Among all reports, the three most common AEs included pyrexia (18.2%), headache (17.9%), and nausea (16.5%). Among serious reports, four deaths appeared to be unrelated to vaccination. Conclusions This 25-year review of VAERS did not identify new or unexpected AEs after HDCV. The vast majority of AEs were non-serious. Injection site reactions, hypersensitivity reactions, and non-specific constitutional symptoms were most frequently reported, similar to findings in pre-licensure studies. PMID:27410239

  3. Serotype IV Streptococcus agalactiae ST-452 has arisen from large genomic recombination events between CC23 and the hypervirulent CC17 lineages

    Science.gov (United States)

    Campisi, Edmondo; Rinaudo, C. Daniela; Donati, Claudio; Barucco, Mara; Torricelli, Giulia; Edwards, Morven S.; Baker, Carol J.; Margarit, Imma; Rosini, Roberto

    2016-01-01

    Streptococcus agalactiae (Group B Streptococcus, GBS) causes life-threatening infections in newborns and adults with chronic medical conditions. Serotype IV strains are emerging both among carriers and as cause of invasive disease and recent studies revealed two main Sequence Types (STs), ST-452 and ST-459 assigned to Clonal Complexes CC23 and CC1, respectively. Whole genome sequencing of 70 type IV GBS and subsequent phylogenetic analysis elucidated the localization of type IV isolates in a SNP-based phylogenetic tree and suggested that ST-452 could have originated through genetic recombination. SNPs density analysis of the core genome confirmed that the founder strain of this lineage originated from a single large horizontal gene transfer event between CC23 and the hypervirulent CC17. Indeed, ST-452 genomes are composed by two parts that are nearly identical to corresponding regions in ST-24 (CC23) and ST-291 (CC17). Chromosome mapping of the major GBS virulence factors showed that ST-452 strains have an intermediate yet unique profile among CC23 and CC17 strains. We described unreported large recombination events, involving the cps IV operon and resulting in the expansion of serotype IV to CC23. This work sheds further light on the evolution of GBS providing new insights on the recent emergence of serotype IV. PMID:27411639

  4. Initiating Events for Multi-Reactor Plant Sites

    Energy Technology Data Exchange (ETDEWEB)

    Muhlheim, Michael David [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Flanagan, George F. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Poore, III, Willis P. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2014-09-01

    Inherent in the design of modular reactors is the increased likelihood of events that initiate at a single reactor affecting another reactor. Because of the increased level of interactions between reactors, it is apparent that the Probabilistic Risk Assessments (PRAs) for modular reactor designs need to specifically address the increased interactions and dependencies.

  5. Multiple mortality events in bats: a global review

    Science.gov (United States)

    O'Shea, Thomas; Cryan, Paul; Hayman, David TH; Plowright, Raina K.; Streicker, Daniel G.

    2016-01-01

    Despite conservation concerns for many species of bats, factors causing mortality in bats have not been reviewed since 1970. Here, we review and qualitatively describe trends in the occurrence and apparent causes of multiple mortality events (MMEs) in bats around the world.

  6. Event studies in Turkey

    Directory of Open Access Journals (Sweden)

    Ulkem Basdas

    2014-09-01

    Full Text Available The primary goal of this paper is to review the event studies conducted for Turkey to in order to identify the common components in their designs. This paper contributes to the existing literature by reviewing all event studies for Turkey for the first time, but more importantly; this review leads to the upcoming event studies on Turkey by highlighting main components of a proper design. Based on the review of 75 studies, it is observed that event studies generally choose BIST-100 (formerly, ISE-100 market index and market adjusted returns with the parametric tests. In general, the studies prefer to rely on one type of model to calculate abnormal returns without discussing the selection of the underlying model. Especially for the event studies focusing on the impact of political events or macroeconomic announcements in Turkey, there is a risk of clustering due to the application of same event date for all observations.

  7. A study of changes in apparent ionospheric reflection height within individual lightning flashes

    Science.gov (United States)

    Somu, Vijaya B.; Rakov, Vladimir A.; Haddad, Michael A.; Cummer, Steven A.

    2015-12-01

    Ionospheric reflection heights estimated using the zero-to-zero and peak-to-peak methods to measure skywave delay relative to the ground wave were compared for 108 first and 124 subsequent strokes at distances greater than 100 km. For either metric there was a considerable decrease in average reflection height for subsequent strokes relative to first strokes. We showed that the observed difference cannot be explained by the difference in frequency content of first and subsequent return-stroke currents. Apparent changes in reflection height (estimated using the peak-to-peak method) within individual flashes for 54 daytime and 11 nighttime events at distances ranging from 50 km to 330 km were compared, and significant differences were found. For daytime conditions, the majority of the flashes showed either decrease (57%) or non-monotonic variation (39%) in reflection height with respect to the immediately preceding stroke. With respect to the first stroke, 91% of the flashes showed monotonic decrease in height. For nighttime flashes, patterns in reflection height changes with respect to the immediately preceding stroke were as follows: 46% no change, 27% monotonic decrease, and 27% non-monotonic variation. When changes were measured with respect to the first stroke, 54% of nighttime flashes showed monotonic decrease and 46% no change. Ionospheric reflection height tends to increase with return-stroke peak current. The observed daytime effects can be explained by (a) the dependence of EMP penetration depth on source intensity, which decreases with stroke order, (b) additional ionization associated with elves, or (c) combination of (a) and (b) above.

  8. Dose-Effect Relationships for Adverse Events After Cranial Radiation Therapy in Long-term Childhood Cancer Survivors

    Energy Technology Data Exchange (ETDEWEB)

    Dijk, Irma W.E.M. van, E-mail: i.w.vandijk@amc.uva.nl [Department of Radiation Oncology, Academic Medical Center, Amsterdam (Netherlands); Cardous-Ubbink, Mathilde C. [Department of Medical Oncology, Academic Medical Center, Amsterdam (Netherlands); Pal, Helena J.H. van der [Department of Medical Oncology, Academic Medical Center, Amsterdam (Netherlands); Department of Pediatric Oncology, Emma Children' s Hospital/Academic Medical Center, Amsterdam (Netherlands); Heinen, Richard C. [Department of Pediatric Oncology, Emma Children' s Hospital/Academic Medical Center, Amsterdam (Netherlands); Leeuwen, Flora E. van [Department of Epidemiology, Netherlands Cancer Institute, Amsterdam (Netherlands); Oldenburger, Foppe; Os, Rob M. van [Department of Radiation Oncology, Academic Medical Center, Amsterdam (Netherlands); Ronckers, Cécile M. [Dutch Childhood Oncology Group, Long-term Effects after Childhood Cancer, The Hague (Netherlands); Schouten–van Meeteren, Antoinette Y.N. [Department of Pediatric Oncology, Emma Children' s Hospital/Academic Medical Center, Amsterdam (Netherlands); Caron, Huib N. [Department of Medical Oncology, Academic Medical Center, Amsterdam (Netherlands); Department of Pediatric Oncology, Emma Children' s Hospital/Academic Medical Center, Amsterdam (Netherlands); Koning, Caro C.E. [Department of Radiation Oncology, Academic Medical Center, Amsterdam (Netherlands); Kremer, Leontien C.M. [Department of Medical Oncology, Academic Medical Center, Amsterdam (Netherlands); Department of Pediatric Oncology, Emma Children' s Hospital/Academic Medical Center, Amsterdam (Netherlands)

    2013-03-01

    Purpose: To evaluate the prevalence and severity of clinical adverse events (AEs) and treatment-related risk factors in childhood cancer survivors treated with cranial radiation therapy (CRT), with the aim of assessing dose-effect relationships. Methods and Materials: The retrospective study cohort consisted of 1362 Dutch childhood cancer survivors, of whom 285 were treated with CRT delivered as brain irradiation (BI), as part of craniospinal irradiation (CSI), and as total body irradiation (TBI). Individual CRT doses were converted into the equivalent dose in 2-Gy fractions (EQD{sub 2}). Survivors had received their diagnoses between 1966 and 1996 and survived at least 5 years after diagnosis. A complete inventory of Common Terminology Criteria for Adverse Events grade 3.0 AEs was available from our hospital-based late-effect follow-up program. We used multivariable logistic and Cox regression analyses to examine the EQD{sub 2} in relation to the prevalence and severity of AEs, correcting for sex, age at diagnosis, follow-up time, and the treatment-related risk factors surgery and chemotherapy. Results: There was a high prevalence of AEs in the CRT group; over 80% of survivors had more than 1 AE, and almost half had at least 5 AEs, both representing significant increases in number of AEs compared with survivors not treated with CRT. Additionally, the proportion of severe, life-threatening, or disabling AEs was significantly higher in the CRT group. The most frequent AEs were alopecia and cognitive, endocrine, metabolic, and neurologic events. Using the EQD{sub 2}, we found significant dose-effect relationships for these and other AEs. Conclusion: Our results confirm that CRT increases the prevalence and severity of AEs in childhood cancer survivors. Furthermore, analyzing dose-effect relationships with the cumulative EQD{sub 2} instead of total physical dose connects the knowledge from radiation therapy and radiobiology with the clinical experience.

  9. Apparent Time Passage and Music Preference by Music and Nonmusic Majors.

    Science.gov (United States)

    Palmquist, Jane E.

    1990-01-01

    Examines how popular music preference in listening exercises influences apparent time passage in a study involving 80 University of Texas, Austin, music and nonmusic major undergraduate students. Shows no significant relationship between music preference and apparent time passage. Finds no significant differences attributable to level of music…

  10. The critical apparent density for the free flow of copper powder

    Directory of Open Access Journals (Sweden)

    MIOMIR G. PAVLOVIC

    2003-06-01

    Full Text Available A method for the determination of the critical apparent density, which permits the free flow of electrodeposited copper powder is discussed. It was found that powders the apparent density of which were larger than 2.3 g/cm3 exhibit free flow. This is in good agreement with the literature data.

  11. Application of BP neural network to semi-solid apparent viscosity simulation

    Institute of Scientific and Technical Information of China (English)

    罗中华; 张质良

    2003-01-01

    Two-layer BP neural network was designed for the semi-solid apparent viscosity simulation. The apparent viscosity simulations of Sn-15%Pb alloy and Al-4.5%Cu-1.5%Mg alloy stirred slurries were carried out. The trained BP neural network forecast the curve of the apparent viscosity versus solid volume fraction of Sn-15%Pb alloy, under the condition of shear rate, =150 s-1, and cooling rate of G=0.33 ℃/min. The simulation results are well agreement with the experimental values given in references The fitted mathematical formula of Sn-15%Pb alloy apparent viscosity, under the condition of the cooling rate of G=0.33 ℃/min, was obtained by optimization method. The results show that the precision of apparent viscosity simulation value by neural network is much better than that of its calculation value by fitted mathematical formula.

  12. Event sponsorship in China

    OpenAIRE

    Y. Fan; Pfitzenmaier, N

    2002-01-01

    Event marketing is currently at the infant stage in China, but holds a great potential in future. This is concluded from an Internet-based survey. The respondents believe that event marketing provides international companies with a viable alternative to the increasingly cluttered mass media, and plays a key role in the integrated marketing communications (IMC). Sponsoring sports and music events is found particularly effective in reaching the opinion leaders and innovators, and establishing f...

  13. LIFE EVENTS AND DEPRESSION

    OpenAIRE

    R N Chatterjee; Mukherjee, S. P.; Nandi, D.N.

    1981-01-01

    SUMMARY The life events occurring in a 6 month period preceding onset of illness in 50 OPD primary depressives were inquired into by a Life Events Inventory and compared with those in a corresponding time period of 50 matched controls. The relation between life events and the depth of depression at initial interview was also studied. The results are analysed and the probable pitfalls discussed.

  14. Event Detection in Tweets

    Directory of Open Access Journals (Sweden)

    Houssem Eddine Dridi

    Full Text Available We present a system for finding, from Twitter data, events that raised the interest of users within a given time period and the important dates for each event. An event is represented by many terms whose frequency increases suddenly at one or more moments during the analysed period. In order to determine the terms (especially the hashtags dealing with a topic, we propose methods to cluster similar terms: phonetic methods adapted to the writing mode used by users and some statistical methods. In order to select the set of events, we used three main criteria: frequency, variation and Tf*Idf.

  15. All-time Apparent Vertical Conductance Interpretation for CLTEM and Its Application

    Institute of Scientific and Technical Information of China (English)

    YanLiangjun; HuWenbao; Xushizhe; LuYi

    2003-01-01

    This paper is based on the transient electromagnetic theory of a thin sheet. The induced EMF formula (as a function of vertical conductance and depth in the central loop transient electromagnetic method) was derived by using the reciprocation law and the formula from the electrical component of EMF induced by a magnetic dipole source over a thin sheet. At the same time, the inversion algorithm of all-time apparent vertical conductance and apparent depth was derived by using the induced EMF and its first derivative. In the transition area there is no distortion for the calculated apparent vertical conductance curve. The location where the curves slope was changing corresponds to an electric interface of the layer. This is because the curve of the slope is directly proportional to the conductivity. Comparing the shapes of the neighboring curves in the same section line, the interfaces of the same layer can be continuously traced, resulting in a high quality CLTEM get-electric section. Theoretical testing with two models shows that the curves of all-time apparent vertical conductance represents the electric property of each layer and its variation. Finally, the authors show application examples of apparent vertical conductance interpretation. The mapped apparent vertical conductance section has fine electric division from the inversion algorithm and is in good co-herence with the inverted resistivity section. This demonstrates that the interpretation method of all-time apparent vertical conductance is feasible and effective

  16. On temporal and spatial distribution of seismic apparent stresses in Yunnan area

    Institute of Scientific and Technical Information of China (English)

    QIN Jia-zheng; QIAN Xiao-dong

    2006-01-01

    motion is applied to a detailed study on the temporal and spatial distribution of the seismic apparent stresses (σa)for the moderate and small earthquakes and two aftershock sequences in Yunnan area. The results show that there exists an obvious non-homogeneity for the seismic apparent stresses in the spatial distribution. The concentrated regions of the high apparent stresses are related to the active places of the moderate and small earthquakes. Before the Dayao M=6.2 earthquake, there was a period in which the apparent stresses were high and the value was 5times of the average value, 0.25 MPa. The relatively high values of apparent stresses distribute around the epicentral area of the major shock and nearby. It indicates that the variation characteristics of the apparent stresses can be taken as a new kind of criterion for the earthquake-risk forecast. Usually the ratio of the apparent stresses of the aftershock sequence σaA to the ones σaM of main shock is less than 1.0.

  17. Safeguards summary event list (SSEL)

    International Nuclear Information System (INIS)

    The List contains nine categories of events involving NRC licensed material or licensees. It is deliberately broad in scope for two main reasons. First, the list is designed to serve as a reference document. It is as complete and accurate as possible. Second, the list is intended to provide as broad a perspective of the nature of licensee-related events as possible. The nine categories of events are as follows: bomb-related events; intrusion events; missing and/or allegedly stolen events; transportation-related events; vandalism events; arson events; firearms-related events; sabotage events; and miscellaneous events

  18. Features, Events, and Processes: Disruptive Events

    International Nuclear Information System (INIS)

    The primary purpose of this analysis is to evaluate seismic- and igneous-related features, events, and processes (FEPs). These FEPs represent areas of natural system processes that have the potential to produce disruptive events (DE) that could impact repository performance and are related to the geologic processes of tectonism, structural deformation, seismicity, and igneous activity. Collectively, they are referred to as the DE FEPs. This evaluation determines which of the DE FEPs are excluded from modeling used to support the total system performance assessment for license application (TSPA-LA). The evaluation is based on the data and results presented in supporting analysis reports, model reports, technical information, or corroborative documents that are cited in the individual FEP discussions in Section 6.2 of this analysis report

  19. Features, Events, and Processes: Disruptive Events

    Energy Technology Data Exchange (ETDEWEB)

    J. King

    2004-03-31

    The primary purpose of this analysis is to evaluate seismic- and igneous-related features, events, and processes (FEPs). These FEPs represent areas of natural system processes that have the potential to produce disruptive events (DE) that could impact repository performance and are related to the geologic processes of tectonism, structural deformation, seismicity, and igneous activity. Collectively, they are referred to as the DE FEPs. This evaluation determines which of the DE FEPs are excluded from modeling used to support the total system performance assessment for license application (TSPA-LA). The evaluation is based on the data and results presented in supporting analysis reports, model reports, technical information, or corroborative documents that are cited in the individual FEP discussions in Section 6.2 of this analysis report.

  20. Adrenal Crisis : Still a Deadly Event in the 21(st) Century

    NARCIS (Netherlands)

    Puar, Troy H K; Stikkelbroeck, Nike M M L; Smans, Lisanne C C J; Zelissen, Pierre M J; Hermus, Ad R M M

    2015-01-01

    Adrenal crisis is a life-threatening medical emergency, associated with a high mortality unless it is appropriately recognized and early treatment is rendered. Despite it being a treatable condition for almost 70 years, failure of adequate preventive measures or delayed treatment has often led to un

  1. Tritium/Helium-3 Apparent Ages of Shallow Ground Water, Portland Basin, Oregon, 1997-98

    Science.gov (United States)

    Hinkle, Stephen R.

    2009-01-01

    Water samples for tritium/helium-3 age dating were collected from 12 shallow monitoring wells in the Portland basin, Oregon, in 1997, and again in 1998. Robust tritium/helium-3 apparent (piston-flow) ages were obtained for water samples from 10 of the 12 wells; apparent ages ranged from 1.1 to 21.2 years. Method precision was demonstrated by close agreement between data collected in 1997 and 1998. Tritium/helium-3 apparent ages generally increase with increasing depth below the water table, and agree well with age/depth relations based on assumptions of effects of recharge rate on vertical ground-water movement.

  2. The effect of particle structure on apparent density of electrolytic copper powder

    Directory of Open Access Journals (Sweden)

    K. I. POPOV

    2001-12-01

    Full Text Available The quantitative microstructural analysis and the sieve analysis of copper powder as well as the scanning electron microscopy analysis of the copper powders particles were performed. It was found that the structure of the copper powder particles determines the apparent density of copper powder. The powder particles from the same fractions of different powders occupy approximately the same volume, but the structure of metallic copper is very different. This causes the difference in apparent densities of copper powder obtained under different conditions. The more dendritic is the structure of powder particles the smaller is the apparent density of copper powder.

  3. Features, Events, and Processes: Disruptive Events

    Energy Technology Data Exchange (ETDEWEB)

    P. Sanchez

    2004-11-08

    The purpose of this analysis report is to evaluate and document the inclusion or exclusion of the disruptive events features, events, and processes (FEPs) with respect to modeling used to support the total system performance assessment for license application (TSPA-LA). A screening decision, either ''Included'' or ''Excluded,'' is given for each FEP, along with the technical basis for screening decisions. This information is required by the U.S. Nuclear Regulatory Commission (NRC) at 10 CFR 63.114 (d), (e), and (f) [DIRS 156605]. The FEPs addressed in this report deal with both seismic and igneous disruptive events, such as fault displacements through the repository and an igneous intrusion into the repository. For included FEPs, this analysis summarizes the implementation of the FEP in TSPA-LA (i.e., how the FEP is included). For excluded FEPs, this analysis provides the technical basis for exclusion from TSPA-LA (i.e., why the FEP is excluded). Previous versions of this report were developed to support the total system performance assessments (TSPA) for various prior repository designs. This revision addresses the repository design for the license application (LA).

  4. The ATLAS Event Builder

    CERN Document Server

    Vandelli, W; Battaglia, A; Beck, H P; Blair, R; Bogaerts, A; Bosman, M; Ciobotaru, M; Cranfield, R; Crone, G; Dawson, J; Dobinson, Robert W; Dobson, M; Dos Anjos, A; Drake, G; Ermoline, Y; Ferrari, R; Ferrer, M L; Francis, D; Gadomski, S; Gameiro, S; Gorini, B; Green, B; Haberichter, W; Haberli, C; Hauser, R; Hinkelbein, C; Hughes-Jones, R; Joos, M; Kieft, G; Klous, S; Korcyl, K; Kordas, K; Kugel, A; Leahu, L; Lehmann, G; Martin, B; Mapelli, L; Meessen, C; Meirosu, C; Misiejuk, A; Mornacchi, G; Müller, M; Nagasaka, Y; Negri, A; Pasqualucci, E; Pauly, T; Petersen, J; Pope, B; Schlereth, J L; Spiwoks, R; Stancu, S; Strong, J; Sushkov, S; Szymocha, T; Tremblet, L; Ünel, G; Vermeulen, J; Werner, P; Wheeler-Ellis, S; Wickens, F; Wiedenmann, W; Yu, M; Yasu, Y; Zhang, J; Zobernig, H; 2007 IEEE Nuclear Science Symposium and Medical Imaging Conference

    2008-01-01

    Event data from proton-proton collisions at the LHC will be selected by the ATLAS experiment in a three-level trigger system, which, at its first two trigger levels (LVL1+LVL2), reduces the initial bunch crossing rate of 40~MHz to $sim$3~kHz. At this rate, the Event Builder collects the data from the readout system PCs (ROSs) and provides fully assembled events to the Event Filter (EF). The EF is the third trigger level and its aim is to achieve a further rate reduction to $sim$200~Hz on the permanent storage. The Event Builder is based on a farm of O(100) PCs, interconnected via a Gigabit Ethernet to O(150) ROSs. These PCs run Linux and multi-threaded software applications implemented in C++. All the ROSs, and substantial fractions of the Event Builder and Event Filter PCs have been installed and commissioned. We report on performance tests on this initial system, which is capable of going beyond the required data rates and bandwidths for Event Building for the ATLAS experiment.

  5. Response of Swimming Paramecia to in situ changes in their apparent weight

    Science.gov (United States)

    Jung, Ilyong; Mickalide, Harry; Valles, James M., Jr.

    2012-02-01

    There is a class of marine micro-organisms that are small enough that low Reynold's number hydrodynamics dictates their swimming mechanics and large enough that the force of gravity exerts a noticeable influence on their motion. Experiments on populations of paramecia suggest that they exert a greater propulsion when swimming against gravity. This negative gravi-kinesis is surprising because it suggests that they sense their tiny apparent weight of about 80 pN. To understand this response in more detail, we are investigating how individual paramecia caudatum change their swimming speed and helical trajectories in response to changes in their apparent weight. We vary the apparent weight with the technique of Magnetic Force Buoyancy Variation employing a high field resistive magnet at the National High Magnetic Field Laboratory. We will present analysis of the swimming for apparent weight changes as large as a factor of 8.

  6. Time operator for the quantum harmonic oscillator resolution of an apparent paradox

    CERN Document Server

    Granik, A; Granik, Alex

    2000-01-01

    An apparent paradox is resolved that concerns the existence of time operators which have been derived for the quantum harmonic oscillator. There is an apparent paradox because, although a time operator is canonically conjugate to the Hamiltonian, it has been asserted that no operator exists that is canonically conjugate to the Hamiltonian. In order to resolve the apparent paradox, we work in a representation where the phase operator is diagonal. The boundary condition on wave functions is such that they be periodic in the phase variable, which is related to the (continuous) eigenvalue of the time operator. Matrix elements of the commutator of the time operator with the Hamiltonian involve the phase variable itself in addition to periodic functions of the phase variable. The Hamiltonian is not hermitian when operating in space that includes the phase variable itself. The apparent paradox is resolved when this non-hermeticity is taken into account correctly in the evaluation of matrix elements of the commutatio...

  7. Model of apparent crystal growth rate and kinetics of seeded precipitation from sodium aluminate solution

    Institute of Scientific and Technical Information of China (English)

    LI Xiao-bin; LIU Zhi-jian; XU Xiao-hui; ZHOU Qiu-sheng; PENG Zhi-hong; LIU Gui-hua

    2005-01-01

    Based on the population balance equation in a batch crystallizer characteristic of seeded precipitation, a model to calculate the rate of apparent crystal growth of aluminum hydroxide from the size distribution was deve-loped. The simulation results indicate that the rate of apparent crystal growth during seeded precipitation exhibits a manifest dependence on the crystal size. In general, there is an obvious increase in the apparent crystal growth rate with the augment in crystal size. The apparent activation energy increases with the increase of characteristic crystal size, which indicates that the growth of small crystals is controlled by surface chemical reaction; it is gradually controlled by both the surface reaction and diffusion with the augment in crystal size.

  8. Apparent viscosity of human blood in a high static magnetic field

    Energy Technology Data Exchange (ETDEWEB)

    Haik, Yousef E-mail: haik@eng.fsu.edu; Pai, Vinay; Chen Chingjen

    2001-07-01

    This study investigates the apparent additive viscosity due to magnetic effects on the human blood. Experimental results show that blood flow rate under gravity decreases by 30% when subjected to a high magnetic field of 10 T. The decrease in the flow rate is due to an increase in the apparent viscosity of the blood due to the magnetic field. A correlation describing the viscosity of blood under these conditions is introduced which depends on the Langevin function and parameters.

  9. A Self-Alignment Algorithm for SINS Based on Gravitational Apparent Motion and Sensor Data Denoising

    OpenAIRE

    Yiting Liu; Xiaosu Xu; Xixiang Liu; Yiqing Yao; Liang Wu; Jin Sun

    2015-01-01

    Initial alignment is always a key topic and difficult to achieve in an inertial navigation system (INS). In this paper a novel self-initial alignment algorithm is proposed using gravitational apparent motion vectors at three different moments and vector-operation. Simulation and analysis showed that this method easily suffers from the random noise contained in accelerometer measurements which are used to construct apparent motion directly. Aiming to resolve this problem, an online sensor data...

  10. Estimating true instead of apparent survival using spatial Cormack-Jolly-Seber models

    Science.gov (United States)

    Schaub, Michael; Royle, J. Andrew

    2014-01-01

    Survival is often estimated from capture–recapture data using Cormack–Jolly–Seber (CJS) models, where mortality and emigration cannot be distinguished, and the estimated apparent survival probability is the product of the probabilities of true survival and of study area fidelity. Consequently, apparent survival is lower than true survival unless study area fidelity equals one. Underestimation of true survival from capture–recapture data is a main limitation of the method.

  11. Linguistic spatial classifications of event domains in narratives of crime

    Directory of Open Access Journals (Sweden)

    Blake Stephen Howald

    2010-07-01

    Full Text Available Structurally, formal definitions of the linguistic narrative minimally require two temporally linked past-time events. The role of space in this definition, based on spatial language indicating where events occur, is considered optional and non-structural. However, based on narratives with a high frequency of spatial language, recent research has questioned this perspective, suggesting that space is more critical than may be readily apparent. Through an analysis of spatially rich serial criminal narratives, it will be demonstrated that spatial information qualitatively varies relative to narrative events. In particular, statistical classifiers in a supervised machine learning task achieve a 90% accuracy in predicting Pre-Crime, Crime, and Post-Crime events based on spatial (and temporal information. Overall, these results suggest a deeper spatial organization of discourse, which not only provides practical event resolution possibilities, but also challenges traditional formal linguistic definitions of narrative.

  12. Anomalous Increase of Apparent Mass in a Silo due to Percolation

    Institute of Scientific and Technical Information of China (English)

    Ram Chand; Abdul Qadir; SHI Qing-Fan; ZHENG Ning; SUN Gang

    2011-01-01

    The apparent mass at the bottom of a granular pile confined in a vertical tube decreases for denser granular packing. We report that the denser granular packing comprising two different diameters of granules augments the apparent mass instead. This anomalous behavior occurs when small granules are stacked on the large ones. In the case of anomalous increase, a percolation effect is found and correlated with the augment of apparent mass at the bottom of the granular column. Finally, the results are qualitatively explained by using the Janssen model.%@@ The apparent mass at the bottom of a granular pile confined in a vertical tube decreases for denser granular packing.We report that the denser granular packing comprising two different diameters of granules augments the apparent mass instead.This anomalous behavior occurs when small granules are stacked on the large ones.In the case of anomalous increase,a percolation effect is found and correlated with the augment of apparent mass at the bottom of the granular column.Finally,the results are qualitatively explained by using the Janssen model.

  13. Forecasting Turbine Icing Events

    DEFF Research Database (Denmark)

    Davis, Neil; Hahmann, Andrea N.; Clausen, Niels-Erik;

    2012-01-01

    In this study, we present a method for forecasting icing events. The method is validated at two European wind farms in with known icing events. The icing model used was developed using current ice accretion methods, and newly developed ablation algorithms. The model is driven by inputs from the WRF...... accumulations, which have not been seen in observations. In addition to the model evaluation we were able to investigate the potential occurrence of ice induced power loss at two wind parks in Europe using observed data. We found that the potential loss during an icing event is large even when the turbine...

  14. Forecasting Turbine Icing Events

    DEFF Research Database (Denmark)

    Davis, Neil; Hahmann, Andrea N.; Clausen, Niels-Erik;

    In this study, we present a method for forecasting icing events. The method is validated at two European wind farms in with known icing events. The icing model used was developed using current ice accretion methods, and newly developed ablation algorithms. The model is driven by inputs from the WRF...... accumulations, which have not been seen in observations. In addition to the model evaluation we were able to investigate the potential occurrence of ice induced power loss at two wind parks in Europe using observed data. We found that the potential loss during an icing event is large even when the turbine...

  15. Computer simulation of nuclear pollutant diffusion from Shimane nuclear power plants and development of an evacuation strategy in the event of a nuclear incident

    International Nuclear Information System (INIS)

    Beginning from Tohoku (northeastern) Earthquake on March 11, an accident at the Fukushima Dai-ichi Nuclear Power Plant resulted in a substantial release of radioactivity to the environment. The accident forced a large number of residents to evacuate from surrounding areas. Moreover, the nuclear incident was life-threatening for the elderly and for people with serious illnesses who were confined in hospital or nursing homes. Strikingly, the causes of death were not directly attributed to radiation exposure but to problems encountered during evacuation. Using nuclear diffusion data from the Fukushima incident, we simulated nuclear pollutant dispersion using computer software A2C in an area of Tottori and Shimane Prefectures surrounding the Shimane Nuclear Power Plant. We generated a model for the spread of nuclear pollutants around the Emergency Planning Zone, id est (i.e.) EPZ. From these findings, we proposed evacuation strategies for residents near the power plant to ensure a safe and reliable escape from nuclear pollutants. Our recommendations include: immediate evacuation from PAZ area (within 5 km), securing indoor shelter in the area of the UPZ (from 5 km to 30 km) and preparations to evacuate further outwards from the nuclear plant site, daytime evacuation within a 30 km area after considering wind direction and velocity, and preparation of a planned evacuation strategy that identifies secure facilities for weaker people in the event of a disaster. (author)

  16. "Universe" event at AIMS

    Science.gov (United States)

    2008-06-01

    Report of event of 11 May 2008 held at the African Institute of Mathematical Sciences (Muizenberg, Cape), with speakers Michael Griffin (Administrator of NASA), Stephen Hawking (Cambridge), David Gross (Kavli Institute, Santa Barbara) and George Smoot (Berkeley).

  17. CCG - News & Events

    Science.gov (United States)

    NCI's Center for Cancer Genomics (CCG) has been widely recognized for its research efforts to facilitiate advances in cancer genomic research and improve patient outcomes. Find the latest news about and events featuring CCG.

  18. RAS Initiative - Events

    Science.gov (United States)

    The NCI RAS Initiative has organized multiple events with outside experts to discuss how the latest scientific and technological breakthroughs can be applied to discover vulnerabilities in RAS-driven cancers.

  19. Solar extreme events

    OpenAIRE

    Hudson, Hugh S.

    2015-01-01

    Solar flares and CMEs have a broad range of magnitudes. This review discusses the possibility of "extreme events," defined as those with magnitudes greater than have been seen in the existing historical record. For most quantitative measures, this direct information does not extend more than a century and a half into the recent past. The magnitude distributions (occurrence frequencies) of solar events (flares/CMEs) typically decrease with the parameter measured or inferred (peak flux, mass, e...

  20. Gargamelle: neutral current event

    CERN Multimedia

    1973-01-01

    This event shows real tracks of particles from the 1200 litre Gargamelle bubble chamber that ran on the PS from 1970 to 1976 and on the SPS from 1976 to 1979. In this image a neutrino passes close to a nucleon and reemerges as a neutrino. Such events are called neutral curent, as they are mediated by the Z0 boson which has no electric charge.

  1. Detecting Priming News Events

    CERN Document Server

    Wu, Di; Yu, Jeffrey Xu; Liu, Zheng

    2012-01-01

    We study a problem of detecting priming events based on a time series index and an evolving document stream. We define a priming event as an event which triggers abnormal movements of the time series index, i.e., the Iraq war with respect to the president approval index of President Bush. Existing solutions either focus on organizing coherent keywords from a document stream into events or identifying correlated movements between keyword frequency trajectories and the time series index. In this paper, we tackle the problem in two major steps. (1) We identify the elements that form a priming event. The element identified is called influential topic which consists of a set of coherent keywords. And we extract them by looking at the correlation between keyword trajectories and the interested time series index at a global level. (2) We extract priming events by detecting and organizing the bursty influential topics at a micro level. We evaluate our algorithms on a real-world dataset and the result confirms that ou...

  2. 1997: notifiable events

    International Nuclear Information System (INIS)

    In May 1998, the German Federal Ministry for the Environment, Nature Conservation, and Rector Safety (BMU) presented the 1997 survey of 'Notifiable events in plants for nuclear fuel fission - nuclear power and research reactors whose maximum power exceeds 50 kW of continuous thermal power - in the Federal Republic of Germany'. Since 1975, the operators of nuclear power plants in the Federal Republic of Germany have been required to report to the nuclear supervisory authorities all notifiable events in accordance with standard national reporting criteria. This official reporting system serves for monitoring the safety status of notifiable plants and use the findings derived from the events reported to improve the safety status of plants within the supervisory procedures where necessary. The reports constitute an important base for the early detection of defects and for preventing the occurrence of similar defects in other plants. In 1997, there were 117 notifiable events in nuclear power plants in the Federal Republic of Germany. None of these events is to be classified as an accident, and in none of the events were dose limits under the German Radiation Protection Ordinance exceeded. (orig.)

  3. Concepts of event-by-event analysis

    Energy Technology Data Exchange (ETDEWEB)

    Stroebele, H. [Universitaet Frankfurt (Germany)

    1995-07-15

    The particles observed in the final state of nuclear collisions can be divided into two classes: those which are susceptible to strong interactions and those which are not, like leptons and the photon. The bulk properties of the {open_quotes}matter{close_quotes} in the reaction zone may be read-off the kinematical characteristics of the particles observable in the final state. These characteristics are strongly dependent on the last interaction these particles have undergone. In a densly populated reaction zone strongly interacting particles will experience many collisions after they have been formed and before they emerge into the asymptotic final state. For the particles which are not sensitive to strong interactions their formation is also their last interaction. Thus photons and leptons probe the period during which they are produced whereas hadrons reflect the so called freeze-out processes, which occur during the late stage in the evolution of the reaction when the population density becomes small and the mean free paths long. The disadvantage of the leptons and photons is their small production cross section; they cannot be used in an analysis of the characteristics of individual collision events, because the number of particles produced per event is too small. The hadrons, on the other hand, stem from the freeze-out period. Information from earlier periods requires multiparticle observables in the most general sense. It is one of the challenges of present day high energy nuclear physics to establish and understand global observables which differentiate between mere hadronic scenarios, i.e superposition of hadronic interactions, and the formation of a partonic (short duration) steady state which can be considered a new state of matter, the Quark-Gluon Plasma.

  4. Holocene cold events on the Tibetan Plateau

    Science.gov (United States)

    Mischke, Steffen; Zhang, Chengjun

    2010-06-01

    A lake sediment core from the eastern Tibetan Plateau was investigated by multi-proxy geochemical, sedimentological and magnetic analyses and its age determined using 14C AMS dating in an approach to use short-lived climate periods for a spatial assessment of the Holocene climate history on the Tibetan Plateau. Six cold events were identified from the Lake Ximencuo record which occurred between 10.3-10.0, 7.9-7.4, 5.9-5.5, 4.2-2.8, 1.7-1.3 and 0.6-0.1 cal ka BP. A comparison with previously published Holocene records from lake and peat sections, ice cores and glacial remains of the Tibetan Plateau revealed that the cold event starting around 4.2 cal ka BP had the most significant and widespread impact on almost all of the examined sites. This cold event lasted about a millennium in the western and central part of the Tibetan Plateau and possibly several hundred years longer at some sites in its eastern realm. The cold event inferred between 7.9 and 7.4 cal ka BP from Lake Ximencuo was recorded at a number of sites on the eastern Tibetan Plateau too and probably corresponds to a cold event identified around 8.2 cal ka BP at the sites on the western and central Tibetan Plateau. The coincidence with the 8.2 ka event of the North Atlantic region implies that the latter exerted a significant environmental impact on the Tibetan Plateau too. The cold spell between 10.3 and 10.0 cal ka BP was recorded at some marginal sites of the Tibetan Plateau but had apparently a less significant environmental impact. The more irregular pattern of cold events between about 7 cal ka BP and the onset of the cold event after 4.2 cal ka BP might be related to the catchment-specific response of the lake sediment and peat accumulation to the termination of the Holocene 'climatic optimum' on the Tibetan Plateau. The final two cold events between 1.7 and 1.3 cal ka BP and in the last several hundred years representing the Little Ice Age are more widely seen on the Tibetan Plateau although they

  5. Thermodynamics of the Apparent Horizon in FRW Universe with Massive Gravity

    Institute of Scientific and Technical Information of China (English)

    LI Hui; ZHANG Yi

    2013-01-01

    Applying Clausius relation with energy-supply defined by the unified first law of thermodynamics formalism to the apparent horizon of a massive gravity model in cosmology proposed lately,the corrected entropic formula of the apparent horizon is obtained with the help of the modified Friedmann equations.This entropy-area relation,together with the identified Misner-Sharp internal energy,verifies the first law of thermodynamics for the apparent horizon with a volume change term for consistency.On the other hand,by means of the corrected entropy-area formula and the Clausius relation δQ =T dS,where the heat flow δQ is the energy-supply of pure matter projecting on the vector ξ tangent to the apparent horizon and should be looked on as the amount of energy crossing the apparent horizon during the time interval dt and the temperature of the apparent horizon for energy crossing during the same interval is 1/(2π(r)A),the modified Friedmann equations governing the dynamical evolution of the universe are reproduced with the known energy density and pressure of massive graviton.The integration constant is found to correspond to a cosmological term which could be absorbed into the energy density of matter.Having established the correspondence of massive cosmology with the unified first law of thermodynamics on the apparent horizon,the validity of the generalized second law of thermodynamics is also discussed by assuming the thermal equilibrium between the apparent horizon and the matter field bounded by the apparent horizon.It is found that,in the limit Hc → 0,which recovers the Minkowski reference metric solution in the flat case,the generalized second law of thermodynamics holds if α3 + 4α4 < 0.Without this condition,even for the simplest model of dRGT massive cosmology with α3 =α4 =0,the generalized second law of thermodynamics could be violated.

  6. Apparent plasticity in functional traits determining competitive ability and spatial distribution: a case from desert.

    Science.gov (United States)

    Xie, Jiang-Bo; Xu, Gui-Qing; Jenerette, G Darrel; Bai, Yong-fei; Wang, Zhong-Yuan; Li, Yan

    2015-07-20

    Species competitive abilities and their distributions are closely related to functional traits such as biomass allocation patterns. When we consider how nutrient supply affects competitive abilities, quantifying the apparent and true plasticity in functional traits is important because the allometric relationships among traits are universal in plants. We propose to integrate the notion of allometry and the classical reaction norm into a composite theoretical framework that quantifies the apparent and true plasticity. Combining the framework with a meta-analysis, a series of field surveys and a competition experiment, we aimed to determine the causes of the dune/interdune distribution patterns of two Haloxylon species in the Gurbantonggut Desert. We found that (1) the biomass allocation patterns of both Haloxylon species in responses to environmental conditions were apparent rather than true plasticity and (2) the allometric allocation patterns affected the plants' competition for soil nutrient supply. A key implication of our results is that the apparent plasticity in functional traits of plants determines their response to environmental change. Without identifying the apparent and true plasticity, we would substantially overestimate the magnitude, duration and even the direction of plant responses in functional traits to climate change.

  7. Thermodynamic Behavior of Friedmann Equations at Apparent Horizon of FRW Universe

    CERN Document Server

    Akbar, M; Cai, Rong-Gen

    2006-01-01

    It is shown that the differential form of Friedmann equations of a FRW universe can be rewritten as a thermodynamical identity $TdS = dE + PdV$ at apparent horizon, where $E$ is the Misner-Sharp energy, $V$ is the volume inside the apparent horizon, and $P$ is the pressure of the perfect fluid in the universe. From the thermodynamic identity one can derive that the apparent horizon $\\tilde r_A$ has associated temperature $T=1/2\\pi \\tilde r_A$ and entropy $S= A/4G$ in Einstein general relativity, where $A$ is the area of apparent horizon. We extend our procedure to the Gauss-Bonnet gravity and more general Lovelock gravity and show that the field equations in these gravities can also be identified as a thermodynamical system satisfying $TdS = dE + PdV$ at the apparent horizon of FRW universe with entropy $S$ being given by expression previously known via black hole thermodynamics.

  8. The apparent contact angle of water droplet on the micro-structured hydrophobic surface

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    The apparent contact angle of Cassie-Baxter state water droplets can be calculated by the existing theoretical formula, but due to the defects of the micro-structured hydrophobic surface and some inevitable tiny disturbances in the experiment, Cassie-Baxter state water droplets will appear partly in Wenzel state, that is, the mixed state water droplets. In this paper, apparent contact angles of Cassie-Baxter state and mixed state water droplets on micro-structured hydrophobic surfaces are compared. The research shows that if the projected area fraction of water-solid F in the Cassie-Baxter formula is replaced by the local projected area fraction of water-solid F′, the apparent contact angles of water droplets in both Cassie-Baxter state and the mixed state can be calculated. Further experimental results indicate that the contact state of water droplets nearby the outermost three-phase contact line plays a more important role in determining the apparent contact angle. This conclusion is significant to the understanding of the apparent contact angle and wetting property.

  9. Correlation between apparent electrical conductivity and chemical and physical attributes of a Rhodic Hapludox

    Directory of Open Access Journals (Sweden)

    Eduardo Leonel Bottega

    2015-07-01

    Full Text Available Precision agriculture has been used as an important technique for localized management of soil fertility. Therefore, it is essential to characterize the spatial variability of chemical and physical attributes of the soil by sampling can represent such variations. This study aimed to analyze the correlation between the apparent electrical conductivity with the chemical and physical attributes of an Rhodic Hapludox. The work was performed on a property located in the Brazilian Cerrado. In an area of 90 hectare were collected 181 georeferenced soil samples at depths from 0.00 to 0.20 meters. The same sites and removal of samples were made apparent electrical conductivity of the soil. The samples were sent to the laboratory to perform the physical and chemical analysis. Were selected randomly sampling 30 points and calculated the Pearson correlation coefficient between the variable physical, chemical and apparent soil electrical conductivity. There was no significant correlation between the apparent electrical conductivity with the soil physical attributes. There was a significant positive correlation of apparent electrical conductivity of the soil at a depth of 0.20 m with the chemical attributes match, remaining phosphorus and zinc.

  10. Osmotic and apparent molar properties of binary mixtures alcohol + 1-butyl-3-methylimidazolium trifluoromethanesulfonate ionic liquid

    International Nuclear Information System (INIS)

    Highlights: ► Osmotic and physical properties of binary mixtures {alcohol + [BMim][TfO]} were measured. ► From experimental data, apparent molar properties and osmotic coefficients were calculated. ► The apparent properties were fitted using a Redlich–Meyer type equation. ► The osmotic coefficients were correlated using the Extended Pitzer model. -- Abstract: In this work, physical properties (densities and speeds of sound) for the binary systems {1-propanol, or 2-propanol, or 1-butanol, or 2-butanol, or 1-pentanol + 1-butyl-3-methylimidazolium trifluoromethanesulfonate} were experimentally measured from T = (293.15 to 323.15) K and at atmospheric pressure. These data were used to calculate the apparent molar volume and apparent molar isentropic compression which were fitted to a Redlich–Meyer type equation. This fit was used to obtain the corresponding apparent molar properties at infinite dilution. On the other hand, the osmotic and activity coefficients and vapor pressures of these binary mixtures were also determined at T = 323.15 K using the vapor pressure osmometry technique. The Extended Pitzer model of Archer was employed to correlate the experimental osmotic coefficients. From the parameters obtained in the correlation, the mean molal activity coefficients and the excess Gibbs free energy for the studied mixtures were calculated

  11. RETRIEVAL EVENTS EVALUATION

    International Nuclear Information System (INIS)

    The purpose of this analysis is to evaluate impacts to the retrieval concept presented in the Design Analysis ''Retrieval Equipment and Strategy'' (Reference 6), from abnormal events based on Design Basis Events (DBE) and Beyond Design Basis Events (BDBE) as defined in two recent analyses: (1) DBE/Scenario Analysis for Preclosure Repository Subsurface Facilities (Reference 4); and (2) Preliminary Preclosure Design Basis Event Calculations for the Monitored Geologic Repository (Reference 5) The objective of this task is to determine what impacts the DBEs and BDBEs have on the equipment developed for retrieval. The analysis lists potential impacts and recommends changes to be analyzed in subsequent design analyses for developed equipment, or recommend where additional equipment may be needed, to allow retrieval to be performed in all DBE or BDBE situations. This analysis supports License Application design and therefore complies with the requirements of Systems Description Document input criteria comparison as presented in Section 7, Conclusions. In addition, the analysis discusses the impacts associated with not using concrete inverts in the emplacement drifts. The ''Retrieval Equipment and Strategy'' analysis was based on a concrete invert configuration in the emplacement drift. The scope of the analysis, as presented in ''Development Plan for Retrieval Events Evaluation'' (Reference 3) includes evaluation and criteria of the following: Impacts to retrieval from the emplacement drift based on DBE/BDBEs, and changes to the invert configuration for the preclosure period. Impacts to retrieval from the main drifts based on DBE/BDBEs for the preclosure period

  12. APPARENT DIGESTIBILTY EXPERIMENT WITH NILE TILAPIA (OREOCHROMIS NILOTICUS FED DIETS CONTAINING CITRULLUS LANATUS SEEDMEAL

    Directory of Open Access Journals (Sweden)

    Wasiu Adeyemi JIMOH

    2015-12-01

    Full Text Available Apparent digestibility coefficients of nutrients in Citrullus lanatus based diets were determined for Nile tilapia (Oreochromis niloticus using AIA as marker or indicator. 150 tilapia fingerlings of average weight 6.12±0.05g were acclimatized for a week, weighed and allotted into five dietary treatments; CTR, DT2, DT3, DT4 and DT5 containing 0, 15, 30, 45 and 60% Citrullus lanatus respectively. The diets were isonitrogenous, isocaloric and isolipidic. Each treatment was replicated three times with ten fish per replicate. Fish were fed 5% body weight on two equal proportions per day. The results from the study indicated that there was no significant variation (p>0.05 in the apparent organic matter and gross energy digestibility coefficients of the diets; that there was significant (p0.05 in the apparent digestibility coefficients of nutrients (protein, energy, lipid and carbohydrates between the diets up to 30% replacement levels for tilapia.

  13. Investigations of the Response of Swimming Paramecia to Variations in their Apparent Weight

    Science.gov (United States)

    Valles, James; Jung, Ilyong; Guevorkian, Karine; Mickalide, Harry; Wagman, Michael

    2011-11-01

    There is a set of micro-organisms that are small enough that they swim at low Reynolds number and large enough that gravity exerts an influence on their behavior Many protists, like paramecia, for example, exhibit negative gravi-taxis by orienting their swimming upward and negative gravi-kinesis by increasing their propulsion when swimming against their apparent weight. It is not clear whether these responses to a very weak force (about 100 pN) are active or passive. We have developed a technique, Magnetic Force Buoyancy Variation, which enables us to vary the apparent weight of the swimmers in situ. We will describe experiments on paramecia conducted at the National High Magnetic Field Laboratory. In particular, we will describe how increasing the apparent weight induces paramecia to accumulate at upper surfaces. A simple force model suggests that this accumulation is a passive response. Supported by NSF-PHY0750360 and a grant to the NHMFL, NSF DMR-0654118.

  14. Apparent Multi-Decadal Trend in Shortwave Cloud Forcing Over the Tropical Pacific

    Energy Technology Data Exchange (ETDEWEB)

    Somerville, R C J; Potter, G L; Kanamitsu, M; Hnilo, J J; Woolen, J

    2000-10-03

    The NCEP/NCAR reanalysis (Kalnay et al. 1996) of atmospheric data beginning in 1948 has provided an opportunity to study a consistent half-century record of assimilated weather observations. Through the examination of several fields, we find an apparent long-term decrease in relative humidity, and hence a decrease in inferred cloud amount, in a large region in the central tropical Pacific. As a result, the apparent short-wave cloud radiative forcing in that region decreased by nearly 15 Wm{sup -2} Over the duration of the period. Two major questions arise from these preliminary results. The first question involves the extent to which the apparent trend over the 50-year period is a real phenomenon rather than an artifact, either of the reanalysis methodology or of observing system evolution. The second question is, if the phenomenon is not entirely an artifact, but is at least partially real, what is its cause?

  15. Reporting of safeguards events

    International Nuclear Information System (INIS)

    On June 9, 1987, the Commission published in the Federal Register a final rule revising the reporting requirements for safeguards events. Safeguards events include actual or attempted theft of special nuclear material (SNM); actual or attempted acts or events which interrupt normal operations at power reactors due to unauthorized use of or tampering with machinery, components, or controls; certain threats made against facilities possessing SNM; and safeguards system failures impacting the effectiveness of the system. The revised rule was effective October 8, 1987. On September 14, 1987, the NRC held a workshop in Bethesda, MD, to answer affected licensees' questions on the final rule. This report documents questions discussed at the September 14 meeting, reflects a completed staff review of the answers, and supersedes previous oral comment on the topics covered

  16. Discrete-Event Simulation

    Directory of Open Access Journals (Sweden)

    Prateek Sharma

    2015-04-01

    Full Text Available Abstract Simulation can be regarded as the emulation of the behavior of a real-world system over an interval of time. The process of simulation relies upon the generation of the history of a system and then analyzing that history to predict the outcome and improve the working of real systems. Simulations can be of various kinds but the topic of interest here is one of the most important kind of simulation which is Discrete-Event Simulation which models the system as a discrete sequence of events in time. So this paper aims at introducing about Discrete-Event Simulation and analyzing how it is beneficial to the real world systems.

  17. Event Marketing : En Begreppsutredning

    OpenAIRE

    Linge, Johan; Skantze Carlsson, Johanna

    2004-01-01

    Event marketing har allt sedan begreppet instiftades runt tiden för OS i Los Angeles 1984 varit starkt praktikerdrivet, vilket även återspeglas i den litteratur som skrivits om fenomenet. Den största delen av denna är av normativ karaktär och antar skepnaden av handböcker snarare än av akademisk litteratur. Bland författarna råder dessutom stor oenighet angående vad som faktiskt innefattas av begreppet event marketing. För den person som försöker förstå vad event marketing handlar om utgör de...

  18. Detection of anomalous events

    Science.gov (United States)

    Ferragut, Erik M.; Laska, Jason A.; Bridges, Robert A.

    2016-06-07

    A system is described for receiving a stream of events and scoring the events based on anomalousness and maliciousness (or other classification). The system can include a plurality of anomaly detectors that together implement an algorithm to identify low-probability events and detect atypical traffic patterns. The anomaly detector provides for comparability of disparate sources of data (e.g., network flow data and firewall logs.) Additionally, the anomaly detector allows for regulatability, meaning that the algorithm can be user configurable to adjust a number of false alerts. The anomaly detector can be used for a variety of probability density functions, including normal Gaussian distributions, irregular distributions, as well as functions associated with continuous or discrete variables.

  19. First Indico Virtual Event

    CERN Document Server

    CERN. Geneva

    2014-01-01

    The first Indico virtual event will take place on February 4th 15:00 and will focus on two main topics The release of Indico v1.2 The migration of the OO Indico backend database (ZODB) to a more standard DBMS It will be fully virtual using the CERN Vidyo service and will foster discussions between developers and administrators of Indico servers worldwide. Connections to the virtual room will be open, but attendees are encouraged to register to the event, in order to be informed of any changes in the organisation if any. If you would like to add a topic of discussion or propose yourself a contribution, please let us know at indico-team@cern.ch. Connection to Vidyo Vidyo connection details are available here CERN Vidyo service documentation can be found here First-time users are encouraged to try the service before connecting to the real event

  20. Color signal integration for color discrimination along a long-range apparent motion trajectory.

    Science.gov (United States)

    Nagai, Takehiro; Kimura, Hiroto; Nakauchi, Shigeki

    2013-01-01

    In contrast to the classical view that fundamental visual attributes such as color and motion are independently processed in the visual system (e.g. Livingstone and Hubel, 1987; Marr, 1982), recent studies have revealed various forms of cross-attribute interactions, such as averaging of color appearance along the motion trajectory of an object (Nishida et al., 2007). In this study, we investigated whether such color signal integration along a motion trajectory can be induced only by motion mechanisms having large receptive fields, without simple integration within direction-selective neurons with small receptive fields, like those in V1. The stimulus consisted of discs with long-range apparent motion along a circular trajectory. The stimulus onset asynchrony (SOA) between disc presentations controlled the strength of the apparent motion perception. We measured observers' sensitivity in detecting color modulation on the discs. The results showed that the measured sensitivity was lowest at SOAs corresponding to the strongest motion perception. This can be interpreted as follows: color signals were integrated along an apparent motion path, and this integration reduced chromatic sensitivity by averaging color signals. Another experiment that controlled apparent motion perception in a different way also supported this idea. However, this integration effect seemed to be linked to responses of motion detectors for the apparent motion stimuli, not directly to perceptual motion representation in the visual system. These results suggest that the human visual system handles color information from retinal inputs regarding moving objects based not only on a retinotopic coordinate but also on object-based coordinates, even when the moving object yields only long-range apparent motion.

  1. Mixing effects on apparent reaction rates and isotope fractionation during denitrification in a heterogeneous aquifer

    Science.gov (United States)

    Green, C.T.; Böhlke, J.K.; Bekins, B.A.; Phillips, S.P.

    2010-01-01

    Gradients in contaminant concentrations and isotopic compositions commonly are used to derive reaction parameters for natural attenuation in aquifers. Differences between field-scale (apparent) estimated reaction rates and isotopic fractionations and local-scale (intrinsic) effects are poorly understood for complex natural systems. For a heterogeneous alluvial fan aquifer, numerical models and field observations were used to study the effects of physical heterogeneity on reaction parameter estimates. Field measurements included major ions, age tracers, stable isotopes, and dissolved gases. Parameters were estimated for the O2 reduction rate, denitrification rate, O 2 threshold for denitrification, and stable N isotope fractionation during denitrification. For multiple geostatistical realizations of the aquifer, inverse modeling was used to establish reactive transport simulations that were consistent with field observations and served as a basis for numerical experiments to compare sample-based estimates of "apparent" parameters with "true" (intrinsic) values. For this aquifer, non-Gaussian dispersion reduced the magnitudes of apparent reaction rates and isotope fractionations to a greater extent than Gaussian mixing alone. Apparent and true rate constants and fractionation parameters can differ by an order of magnitude or more, especially for samples subject to slow transport, long travel times, or rapid reactions. The effect of mixing on apparent N isotope fractionation potentially explains differences between previous laboratory and field estimates. Similarly, predicted effects on apparent O2 threshold values for denitrification are consistent with previous reports of higher values in aquifers than in the laboratory. These results show that hydrogeological complexity substantially influences the interpretation and prediction of reactive transport. ?? 2010 by the American Geophysical Union.

  2. DER 83: outstanding events

    International Nuclear Information System (INIS)

    The DER's activity is presented through 82 ''outstanding events''. Each one is a stage in the effort of research and development of the DER. These events concern the following fields: new applications of electric power for customers; environment protection and new energy sources; improvements of electric power production units; electrical materials; electric network planning and control; computer codes. In the production field, one deals more particularly with nuclear reactor safety studies: analysis of the behaviour of different components; reactor safety experiments; reliability of different systems (safety, communications...)

  3. Electrocardiogram events detection

    OpenAIRE

    Teixeira, João Paulo; Lopes, Vanda

    2011-01-01

    This work aims to create a system of medical diagnosis of the Electrocardiogram (ECG). The events of the ECG are related with the functioning of the heart and different disorders of the heart functioning have their own ECG pattern allowing the connection between ECG patterns and cardiac disorders. For this purpose, we present here an algorithm that detects the P, QRS and T events of the ECG under MATLAB environment. The algorithm is based in two techniques. The search for picks and valleys an...

  4. Blogimarkkinointi : Case: Laurea Events

    OpenAIRE

    Kronberg, Anna

    2014-01-01

    Tämän opinnäytetyön toimeksiantaja oli Laurea Events. Työn aiheena oli blogimarkkinointi. Opinnäytetyön tavoitteena oli tuoda esiin blogimarkkinoinnin käytettävyyteen vaikuttavia tekijöitä ja kehittää sisältöideoita blogiin, jolla Laurea Eventsin palveluita ja Laureaammattikorkeakoulun restonomikoulutusta voidaan markkinoida mielekkäämmin perinteisen markkinoinnin ohella. Opinnäytetyön tarkoituksena oli se, että toimeksiantaja Laurea Events voi hyödyntää saatuja tuloksia blogim...

  5. Events and Effects

    DEFF Research Database (Denmark)

    Rytter, Mikkel

    2010-01-01

    Analyzing the period of ‘intensive transnationalism’ among Pakistani migrants in Denmark precipitated by the 2005 earthquake in Kashmir, this article explores the relationship between events and effects on a global scale. One significant initiative after the disaster was the founding of an ad hoc......, and national identity politics in Denmark. Despite the medical doctors’ efforts and intentions, the out- come was framed by 9/11, which has become the major critical event of the decade—one that has supported a developing cleavage between the Danish majority and Denmark’s Muslim immigrant minority....

  6. Ablative radioactive iodine therapy for apparently localized thyroid carcinoma. A decision analytic perspective

    Energy Technology Data Exchange (ETDEWEB)

    Wong, J.B.; Kaplan, M.M.; Meyer, K.B.; Pauker, S.G. (Tufts Univ. School of Medicine, Boston, MA (USA))

    1990-09-01

    Adjuvant therapy with ablative radioiodine after surgical resection of apparently localized thyroid carcinoma remains controversial because of the favorable prognosis of thyroid carcinoma and the risk of leukemia from the radioiodine. No controlled trials have been performed to examine this issue. We constructed a decision analytic model to examine whether patients with apparently localized thyroid carcinoma should receive radioiodine. Our analysis suggests that radioiodine modestly improves life expectancy by 2 to 15 months, depending on the patient's age and sex. This model predicts that the benefit of a reduction in the likelihood of recurrence outweighs the risk of leukemia from radioiodine.

  7. Interacting entropy-corrected holographic dark energy with apparent horizon as an infrared cutoff

    OpenAIRE

    Khodam-Mohammadi, A.; Malekjani, M.

    2011-01-01

    In this work we consider the entropy-corrected version of interacting holographic dark energy (HDE), in the non-flat universe enclosed by apparent horizon. Two corrections of entropy so-called logarithmic 'LEC' and power-law 'PLEC' in HDE model with apparent horizon as an IR-cutoff are studied. The ratio of dark matter to dark energy densities $u$, equation of state parameter $w_D$ and deceleration parameter $q$ are obtained. We show that the cosmic coincidence is satisfied for both interacti...

  8. Prestanda av användargränssnitt i cross-platform-appar

    OpenAIRE

    Lygnebrandt, Emil; Holm, Jonathan

    2016-01-01

    Syftet med denna studie är att undersöka fördröjningsskillnader inom användargränssnitt mellan native­utvecklade appar (utveckling till varje plattform) och appar av typen generated apps. Eftersom arbetet syftar till att bidra med information om prestanda ansågs en experimentell metod vara det bästa valet. Mätning av laddningstider gjordes med hjälp av en videokamera som filmade utförandet av experimenten vilket gjorde metoden simpel och liknar det som en användare kommer att uppleva. Avgräns...

  9. Tunnelling phenomenon near an apparent horizon in two-dimensional dilaton gravity

    CERN Document Server

    Cao, Li-Ming; Peng, Yuxuan

    2016-01-01

    Based on the definition of the apparent horizon in a general two-dimensional dilaton gravity theory, we analyze the tunnelling phenomenon of the apparent horizon by using Hamilton-Jacobi method. In this theory the definition of the horizon is very different from those in higher-dimensional gravity theories. The spectrum of the radiation is obtained and the temperature of the radiation is read out from this spectrum and it satisfies the usual relationship with the surface gravity. Besides, the calculation with Parikh's null geodesic method for a simple example conforms to our result in general stationary cases.

  10. Two-dimensional modeling of apparent resistivity pseudosections in the Cerro Prieto region

    Energy Technology Data Exchange (ETDEWEB)

    Vega, R.; Martinez, M.

    1981-01-01

    Using a finite-difference program (Dey, 1976) for two-dimensional modeling of apparent resistivity pseudosections obtained by different measuring arrays, four apparent resistivity pseudosections obtained at Cerro Prieto with a Schlumberger array by CFE personnel were modeled (Razo, 1978). Using geologic (Puente and de la Pena, 1978) and lithologic (Diaz, et al., 1981) data from the geothermal region, models were obtained which show clearly that, for the actual resistivity present in the zone, the information contained in the measured pseudosections is primarily due to the near-surface structure and does not show either the presence of the geothermal reservoir or the granitic basement which underlies it.

  11. Dynamics of three anomalous SST events in the Coral Sea

    Science.gov (United States)

    Schiller, A.; Ridgway, K. R.; Steinberg, C. R.; Oke, P. R.

    2009-03-01

    Variability of the circulation in the Coral Sea, accompanied by large heat transport anomalies, has the potential to have detrimental impacts on underlying ecosystems, including the Great Barrier Reef. In this study we analyze the dynamics of three events, characterized by extremes in sea-surface temperature, as simulated in an eddy-resolving ocean reanalysis. We show that a cooling in April 1997 results from strong wind anomalies and is supported by vertical and horizontal advective heat losses. A warm event in October 1998 is attributable to a heat gain by horizontal advection. A heat budget of the mixed-layer within a closed box shows that warm anomalies in January 2002 involve a quasi-balance between horizontal advection and vertical entrainment with a large local heat gain through the ocean surface near-shore that apparently caused a coral bleaching event. The dynamics of these extreme events are all quite different, with both local and remote influences.

  12. Language As Social Event.

    Science.gov (United States)

    Harste, Jerome C.

    A taxonomy developed for the study of the growth and development of written language from the perspective of social event was tested with a group of 68 children, aged three to six years. The subjects were presented with a wide variety of environmental print messages (road signs, toys, fast food signs, and household products) and were questioned…

  13. Event-as-participation

    DEFF Research Database (Denmark)

    Kjeldsen, Lena

    2016-01-01

    herved skabe en ny begivenhed- en begivenhed der gennem artiklen konceptualiseres som ”event-as-participation”. Omdrejningspunktet i denne artikel er således de ændrede dynamikker forårsaget af samspillet mellem transmitterede politiske begivenheder og sociale netværkssider. Praksissen skaber nye...

  14. On Objects and Events

    DEFF Research Database (Denmark)

    Eugster, Patrick Thomas; Guerraoui, Rachid; Damm, Christian Heide

    2001-01-01

    This paper presents linguistic primitives for publish/subscribe programming using events and objects. We integrate our primitives into a strongly typed object-oriented language through four mechanisms: (1) serialization, (2) multiple sub typing, (3) closures, and (4) deferred code evaluation. We...

  15. ATLAS "Splash event" 2008

    CERN Multimedia

    ATLAS, Experiment

    2014-01-01

    "Splash events": As the LHC was being tuned up on 10 September 2008, beam was initially directed at beam collimators just outside the detector, so that a splash of particles would fill much of the detector allowing ATLAS experimenters to prepare the detector for actual running.

  16. "Near-miss" obstetric events and maternal deaths in Sagamu, Nigeria: a retrospective study

    Directory of Open Access Journals (Sweden)

    Daniel Olusoji J

    2005-11-01

    Full Text Available Abstract Aim To determine the frequency of near-miss (severe acute maternal morbidity and the nature of near-miss events, and comparatively analysed near-miss morbidities and maternal deaths among pregnant women managed over a 3-year period in a Nigerian tertiary centre. Methods Retrospective facility-based review of cases of near-miss and maternal death which occurred between 1 January 2002 and 31 December 2004. Near-miss case definition was based on validated disease-specific criteria, comprising of five diagnostic categories: haemorrhage, hypertensive disorders in pregnancy, dystocia, infection and anaemia. The near-miss morbidities were compared with maternal deaths with respect to demographic features and disease profiles. Mortality indices were determined for various disease processes to appreciate the standard of care provided for life-threatening obstetric conditions. The maternal death to near-miss ratios for the three years were compared to assess the trend in the quality of obstetric care. Results There were 1501 deliveries, 211 near-miss cases and 44 maternal deaths. The total near-miss events were 242 with a decreasing trend from 2002 to 2004. Demographic features of cases of near-miss and maternal death were comparable. Besides infectious morbidity, the categories of complications responsible for near-misses and maternal deaths followed the same order of decreasing frequency. Hypertensive disorders in pregnancy and haemorrhage were responsible for 61.1% of near-miss cases and 50.0% of maternal deaths. More women died after developing severe morbidity due to uterine rupture and infection, with mortality indices of 37.5% and 28.6%, respectively. Early pregnancy complications and antepartum haemorrhage had the lowest mortality indices. Majority of the cases of near-miss (82.5% and maternal death (88.6% were unbooked for antenatal care and delivery in this hospital. Maternal mortality ratio for the period was 2931.4 per 100

  17. RETRIEVAL EVENTS EVALUATION

    Energy Technology Data Exchange (ETDEWEB)

    T. Wilson

    1999-11-12

    The purpose of this analysis is to evaluate impacts to the retrieval concept presented in the Design Analysis ''Retrieval Equipment and Strategy'' (Reference 6), from abnormal events based on Design Basis Events (DBE) and Beyond Design Basis Events (BDBE) as defined in two recent analyses: (1) DBE/Scenario Analysis for Preclosure Repository Subsurface Facilities (Reference 4); and (2) Preliminary Preclosure Design Basis Event Calculations for the Monitored Geologic Repository (Reference 5) The objective of this task is to determine what impacts the DBEs and BDBEs have on the equipment developed for retrieval. The analysis lists potential impacts and recommends changes to be analyzed in subsequent design analyses for developed equipment, or recommend where additional equipment may be needed, to allow retrieval to be performed in all DBE or BDBE situations. This analysis supports License Application design and therefore complies with the requirements of Systems Description Document input criteria comparison as presented in Section 7, Conclusions. In addition, the analysis discusses the impacts associated with not using concrete inverts in the emplacement drifts. The ''Retrieval Equipment and Strategy'' analysis was based on a concrete invert configuration in the emplacement drift. The scope of the analysis, as presented in ''Development Plan for Retrieval Events Evaluation'' (Reference 3) includes evaluation and criteria of the following: Impacts to retrieval from the emplacement drift based on DBE/BDBEs, and changes to the invert configuration for the preclosure period. Impacts to retrieval from the main drifts based on DBE/BDBEs for the preclosure period.

  18. An investigation of the apparent breast cancer epidemic in France: screening and incidence trends in birth cohorts

    Directory of Open Access Journals (Sweden)

    Olsen Jørn

    2011-09-01

    Full Text Available Abstract Background Official descriptive data from France showed a strong increase in breast-cancer incidence between 1980 to 2005 without a corresponding change in breast-cancer mortality. This study quantifies the part of incidence increase due to secular changes in risk factor exposure and in overdiagnosis due to organised or opportunistic screening. Overdiagnosis was defined as non progressive tumours diagnosed as cancer at histology or progressive cancer that would remain asymptomatic until time of death for another cause. Methods Comparison between age-matched cohorts from 1980 to 2005. All women residing in France and born 1911-1915, 1926-1930 and 1941-1945 are included. Sources are official data sets and published French reports on screening by mammography, age and time specific breast-cancer incidence and mortality, hormone replacement therapy, alcohol and obesity. Outcome measures include breast-cancer incidence differences adjusted for changes in risk factor distributions between pairs of age-matched cohorts who had experienced different levels of screening intensity. Results There was an 8-fold increase in the number of mammography machines operating in France between 1980 and 2000. Opportunistic and organised screening increased over time. In comparison to age-matched cohorts born 15 years earlier, recent cohorts had adjusted incidence proportion over 11 years that were 76% higher [95% confidence limits (CL 67%, 85%] for women aged 50 to 64 years and 23% higher [95% CL 15%, 31%] for women aged 65 to 79 years. Given that mortality did not change correspondingly, this increase in adjusted 11 year incidence proportion was considered as an estimate of overdiagnosis. Conclusions Breast cancer may be overdiagnosed because screening increases diagnosis of slowly progressing non-life threatening cancer and increases misdiagnosis among women without progressive cancer. We suggest that these effects could largely explain the reported

  19. Linseed dietary fibers reduce apparent digestibility of energy and fat and weight gain in growing rats

    DEFF Research Database (Denmark)

    Kristensen, M.; Knudsen, K. E. B.; Jørgensen, H.;

    2013-01-01

    Dietary fibers (DF) may affect energy balance, an effect often ascribed to the viscous nature of some water soluble DF, which affect luminal viscosity and thus multiple physiological processes. We have tested the hypothesis that viscous linseed DF reduce apparent nutrient digestibility, and limit...

  20. Gas Phase Pressure Effects on the Apparent Thermal Conductivity of JSC-1A Lunar Regolith Simulant

    Science.gov (United States)

    Yuan, Zeng-Guang; Kleinhenz, Julie E.

    2011-01-01

    Gas phase pressure effects on the apparent thermal conductivity of a JSC-1A/air mixture have been experimentally investigated under steady state thermal conditions from 10 kPa to 100 kPa. The result showed that apparent thermal conductivity of the JSC-1A/air mixture decreased when pressure was lowered to 80 kPa. At 10 kPa, the conductivity decreased to 0.145 W/m/degree C, which is significantly lower than 0.196 W/m/degree C at 100 kPa. This finding is consistent with the results of previous researchers. The reduction of the apparent thermal conductivity at low pressures is ascribed to the Knudsen effect. Since the characteristic length of the void space in bulk JSC-1A varies over a wide range, both the Knudsen regime and continuum regime can coexist in the pore space. The volume ratio of the two regimes varies with pressure. Thus, as gas pressure decreases, the gas volume controlled by Knudsen regime increases. Under Knudsen regime the resistance to the heat flow is higher than that in the continuum regime, resulting in the observed pressure dependency of the apparent thermal conductivity.

  1. Standardization of soil apparent electrical conductivity using multi-temporal surveys across multiple production fields

    Science.gov (United States)

    Apparent soil electrical conductivity (ECa) is an efficient technique for understanding within-field variability of physical and chemical soil characteristics. Commercial devices are readily available for collecting ECa on whole fields and used broadly for crop management in precision agriculture; h...

  2. Concurrent temporal stability of the apparent electrical conductivity and soil water content

    Science.gov (United States)

    Knowledge of spatio-temporal soil water content (SWC) variability within agricultural fields is useful to improve crop management. Spatial patterns of soil water contents can be characterized using the temporal stability analysis, however high density sampling is required. Soil apparent electrical c...

  3. 45 CFR 73.735-904 - Resolution of apparent or actual conflicts of interest.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Resolution of apparent or actual conflicts of interest. 73.735-904 Section 73.735-904 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL... activity giving rise to the problem: (1) Bears a direct or indirect relationship to...

  4. The effect of interaural-time-difference fluctuations on apparent source width

    DEFF Research Database (Denmark)

    Käsbach, Johannes; May, Tobias; Oskarsdottir, Gudrun;

    2014-01-01

    For the perception of spaciousness, the temporal fluctuations of the interaural time differences (ITDs) and interaural level differences (ILDs) provide important binaural cues. One major characteristic of spatial perception is apparent source width (ASW), which describes the perceived width of a ...

  5. Gamow's bicycle: The Appearance of Bodies at Relativistic Speeds and Apparent Superluminal Velocities

    CERN Document Server

    Nowojewski, A

    2005-01-01

    A human creates an image basing on the information delivered by photons that arrived at his retina simultaneously. Due to finite and constant velocity of light these photons left the moving body at different times, since not all points of the body are equidistant. In other words its image represents the body as it was in several different times i.e. it is distorted and does not correspond to its real appearance. The useful experimental arrangement is set and then used to derive the general expression that transforms two-dimensional stationary shapes to their apparent forms, which could be photographed once they are set in motion. It is then used to simulate the so-called Gamow's bicycle combined out of circles and straight lines. The simulation outlines two important aspects of bike's motion: apparent distance of two points and apparent velocity which are then discussed thoroughly. It is found that the approaching body is elongated and its apparent speed is greater than its real one (under certain conditions ...

  6. Structure of Gamma-Ray Burst jets: intrinsic versus apparent properties

    CERN Document Server

    Salafia, O S; Pescalli, A; Ghirlanda, G; Nappo, F

    2015-01-01

    With this paper we introduce the concept of apparent structure of a GRB jet, as opposed to its intrinsic structure. The latter is customarily defined specifying the functions epsilon(theta) (the energy emitted per jet unit solid angle) and Gamma(theta) (the Lorentz factor of the emitting material); the apparent structure is instead defined by us as the isotropic equivalent energy E_iso(theta_v) as a function of the viewing angle theta_v. We show how to predict the apparent structure of a jet given its intrinsic structure. We find that a Gaussian intrinsic structure yields a power law apparent structure: this opens a new viewpoint on the Gaussian (which can be understood as a proxy for a realistic narrow, well collimated jet structure) as a possible candidate for a quasi-universal GRB jet structure. We show that such a model (a) is consistent with recent constraints on the observed luminosity function of GRBs; (b) implies fewer orphan afterglows with respect to the standard uniform model; (c) can break out the...

  7. Influence of feeding various phosphorus sources on apparent digestibility of phosphorus in dairy cows

    NARCIS (Netherlands)

    Ekelund, A.; Sporndly, R.; Valk, H.; Murphy, M.

    2003-01-01

    The present investigated differences in the apparent digestibility of phosphorus (ADP) in lactating cows fed various feed materials containing organic forms of phosphorus (P) or a highly available inorganic phosphorus source. Cows milking an average of 36 kg energy corrected milk (ECM) were used in

  8. Association of early CT abnormalities, infarct size, and apparent diffusion coefficient reduction in acute ischemic stroke

    NARCIS (Netherlands)

    Somford, DM; Marks, MP; Thijs, VN; Tong, DC

    2004-01-01

    BACKGROUND AND PURPOSE: Diffusion-weighted (DW) imaging is more sensitive for early ischemia than CT, and apparent diffusion coefficient (ADC) mapping permits quantification of the severity of cytotoxic edema. We examined the relationship between early CT findings, ischemic lesion volume on DW image

  9. [Effect of drought stress on apparent resource utilization efficiency of Quercus mongolica].

    Science.gov (United States)

    Wang, Miao; Dai, Limin; Ji, Lanzhu

    2002-03-01

    To study the effect of drought stress on the physiological characteristics and resource utilization efficiency of Quercus mongolica, a dominant species in the Korean pine broad-leaved forest in Changbai Mountain, a comparative experiment was carried out under three soil moisture gradients as 85%-100% (high water, CK), 65%-85% (Medium water, MW), and 45%-65% (low water, LW) of field water-bolding capacity. The results showed that net photosynthetic rate, stomatal conduction, transpiration rate, water utilization efficiency, apparent CO2 utilization efficiency and apparent light utilization efficiency of the seedlings of Quercus mongolica were all significantly influenced by simulated drought stress. Stomatal conduction, water utilization efficiency and net photosynthetic rate of large tress of Quercus mongolica were affected by the soil drought stress, while transpiration rate, apparent CO2 utilization efficiency, and apparent light utilization efficiency were not influenced. Moderate soil water condition could greatly increase gas exchange and water utilization efficiency. These results indicated that the responses of gas exchange and resource utilization efficiency to various water stresses were different. Quercus mongolica was a species with variable resistance to drought stress, and the resistance would be improved by drought stress, especially moderate water stress. PMID:12132152

  10. APPARENT CROSS-FIELD SUPERSLOW PROPAGATION OF MAGNETOHYDRODYNAMIC WAVES IN SOLAR PLASMAS

    Energy Technology Data Exchange (ETDEWEB)

    Kaneko, T.; Yokoyama, T. [Department of Earth and Planetary Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033 (Japan); Goossens, M.; Doorsselaere, T. Van [Centre for Mathematical Plasma Astrophysics, Katholieke Universiteit Leuven, Celestijnenlaan 200B, Bus 2400, B-3001 Herverlee (Belgium); Soler, R.; Terradas, J. [Departament de Física, Universitat de les Illes Balears, E-07122 Palma de Mallorca (Spain); Wright, A. N., E-mail: kaneko@eps.s.u-tokyo.ac.jp [School of Mathematics and Statistics, University of St Andrews, St Andrews, KY16 9SS (United Kingdom)

    2015-10-20

    In this paper we show that the phase-mixing of continuum Alfvén waves and/or continuum slow waves in the magnetic structures of the solar atmosphere as, e.g., coronal arcades, can create the illusion of wave propagation across the magnetic field. This phenomenon could be erroneously interpreted as fast magnetosonic waves. The cross-field propagation due to the phase-mixing of continuum waves is apparent because there is no real propagation of energy across the magnetic surfaces. We investigate the continuous Alfvén and slow spectra in two-dimensional (2D) Cartesian equilibrium models with a purely poloidal magnetic field. We show that apparent superslow propagation across the magnetic surfaces in solar coronal structures is a consequence of the existence of continuum Alfvén waves and continuum slow waves that naturally live on those structures and phase-mix as time evolves. The apparent cross-field phase velocity is related to the spatial variation of the local Alfvén/slow frequency across the magnetic surfaces and is slower than the Alfvén/sound velocities for typical coronal conditions. Understanding the nature of the apparent cross-field propagation is important for the correct analysis of numerical simulations and the correct interpretation of observations.

  11. 75 FR 51869 - CAFTA-DR Consultation Request Regarding Guatemala's Apparent Failure to Effectively Enforce its...

    Science.gov (United States)

    2010-08-23

    ... Enforce its Labor Laws AGENCY: Office of the United States Trade Representative. ACTION: Notice; request... Government of Guatemala to discuss Guatemala's apparent failure to meet its obligation under Article 16.2.1(a) to effectively enforce its labor laws. The consultations request may be found at...

  12. Irreversible thermodynamics of dark energy on the entropy-corrected apparent horizon

    Energy Technology Data Exchange (ETDEWEB)

    Karami, K; Sahraei, N [Department of Physics, University of Kurdistan, Pasdaran Street, Sanandaj (Iran, Islamic Republic of); Jamil, M, E-mail: KKarami@uok.ac.i, E-mail: mjamil@camp.nust.edu.p [Center for Advanced Mathematics and Physics (CAMP), National University of Sciences and Technology (NUST), Islamabad (Pakistan)

    2010-10-15

    We study the irreversible (non-equilibrium) thermodynamics of the Friedmann-Robertson-Walker (FRW) universe containing only dark energy. Using the modified entropy-area relation that is motivated by loop quantum gravity, we calculate the entropy-corrected form of the apparent horizon of the FRW universe.

  13. Dietary factors associated with plasma high molecular weight and total adiponectin levels in apparently healthy women

    NARCIS (Netherlands)

    Yannakoulia, Mary; Yiannakouris, Nikos; Melistas, Labros; Fappa, Evaggelia; Vidra, Nikoletta; Kontogianni, Meropi D; Mantzoros, Christos S

    2008-01-01

    OBJECTIVE: Our aim was to investigate associations between dietary factors and high molecular weight (HMW) as well as total adiponectin in a sample of apparently healthy adult Mediterranean women. DESIGN AND METHODS: Two hundred and twenty women were enrolled in this study. Anthropometric and body c

  14. Unified first law and the thermodynamics of the apparent horizon in the FRW universe

    International Nuclear Information System (INIS)

    In this paper we revisit the relation between the Friedmann equations and the first law of thermodynamics. We find that the unified first law first proposed by Hayward to treat the outertrapping horizon of a dynamical black hole can be used to the apparent horizon (a kind of inner trapping horizon in the context of the FRW cosmology) of the FRW universe. We discuss three kinds of gravity theorties: Einstein theory, Lovelock thoery, and scalar-tensor theory. In Einstein theory, the first law of thermodynamics is always satisfied on the apparent horizon. In Lovelock theory, treating the higher derivative terms as an effective energy-momentum tensor, we find that this method can give the same entropy formula for the apparent horizon as that of black hole horizon. This implies that the Clausius relation holds for the Lovelock theory. In scalar-tensor gravity, we find, by using the same procedure, the Clausius relation no longer holds. This indicates that the apparent horizon of the FRW universe in the scalar-tensor gravity corresponds to a system of nonequilibrium thermodynamics. We show this point by using the method developed recently by Eling et al. for dealing with the f(R) gravity

  15. Analytical criteria for predicting apparent digestibility of soybean protein in preruminant calves.

    Science.gov (United States)

    Lalles, J P; Tukur, H M; Toullec, R; Miller, B G

    1996-03-01

    A series of experiments on the use of soybean as a protein source in milk replacers for veal calves was undertaken to determine the relationships between the physicochemical and antinutritional properties and apparent digestibilities of nine soybean products. Soybean provided between 58 and 71% of dietary CP, and skim milk or whey powder provided the remainder. Soybean products were analyzed for CP, native protein, aggregated protein, carbohydrate-linked protein, peptides, antitryptic activity, and immunoreactivity of lectin, glycinin, alpha-conglycinin, and beta-conglycinin. The apparent digestibility of N calculated for soybean protein varied between 59 and 84%. Simple linear correlations were significant between apparent digestibility of soybean N and concentrations of native protein, antitryptic activity, glycinin, alpha-conglycinin, and beta-conglycinin. However, only variation in antitryptic activity, alpha-conglycinin, and beta-conglycinin contributed significantly to an explanation for the variation in apparent digestibility of soybean N in a multiple linear equation. Under our experimental conditions, beta-conglycinin was the best predictor of digestibility of soybean N. Antitryptic activity became the best predictor when soybean products had no detectable beta-conglycinin. PMID:8708110

  16. Definition of management zones in coffee production fields based on apparent soil electrical conductivity

    Directory of Open Access Journals (Sweden)

    Domingos Sárvio Magalhães Valente

    2012-06-01

    Full Text Available Fertilizer application at variable rates requires dense sampling to determine the resulting field spatial variability. Defining management zones is a technique that facilitates the variable-rate application of agricultural inputs. The apparent electrical conductivity of the soil is an important factor in explaining the variability of soil physical-chemical properties. Thus, the objective of this study was to define management zones for coffee (Coffea Arabica L. production fields based on spatial variability of the apparent electrical conductivity of the soil. The resistivity method was used to measure the apparent soil electrical conductivity. Soil samples were collected to measure the chemical and physical soil properties. The maps of spatial variability were generated using ordinary kriging method. The fuzzy k-means algorithm was used to delimit the management zones. To analyze the agreement between the management zones and the soil properties, the kappa coefficients were calculated. The best results were obtained for the management zones defined using the apparent electrical conductivity of the soil and the digital elevation model. In this case, the kappa coefficient was 0.45 for potassium, which is an element that is associated with quality coffee. The other variable that had a high kappa coefficient was remaining phosphorous; the coefficient obtained was 0.49. The remaining phosphorus is an important parameter for determining which fertilizers and soil types to study.

  17. Primary School Students' Ideas Concerning the Apparent Movement of the Moon

    Science.gov (United States)

    Starakis, John; Halkia, Krystallia

    2010-01-01

    In the present study, primary school students' ideas concerning the apparent movement of the Moon are investigated. The research was carried out in five primary schools of Athens (Greece) with a sample of forty (40), fifth and sixth grade students. Semistructured interviews were used to gather scientific data and students had the opportunity to…

  18. High bone mineral apparent density in children with X-linked hypophosphatemia

    DEFF Research Database (Denmark)

    Beck-Nielsen, Signe; Brixen, K; Gram, J;

    2013-01-01

    Bone mineral apparent density (BMAD) in children with X-linked hypophosphatemia (XLH) was evaluated, as they are unlikely to have extra-skeletal ossifications contributing to the elevated bone mineral density of the spine in adult patients. Children with XLH also had significantly higher BMAD of ...

  19. Profile Method for Measuring Apparent Optical Parameters (AOP)in Class-Ⅱ Waters

    Institute of Scientific and Technical Information of China (English)

    李铜基; 陈清莲

    2004-01-01

    The profile method is the principal method first to be chosen to measure the apparent optical parameters of waters. This paper first introduces the profile method briefly,then modifies the applied algorithm in the light of the properties of the class- Ⅱ waters and lastly, analyses the effect of application.

  20. To Think or Not to Think: The Apparent Paradox of Expert Skill in Music Performance

    Science.gov (United States)

    Geeves, Andrew; McIlwain, Doris J. F.; Sutton, John; Christensen, Wayne

    2014-01-01

    Expert skill in music performance involves an apparent paradox. On stage, expert musicians are required accurately to retrieve information that has been encoded over hours of practice. Yet they must also remain open to the demands of the ever-changing situational contingencies with which they are faced during performance. To further explore this…

  1. Stewart analysis of apparently normal acid-base state in the critically ill

    NARCIS (Netherlands)

    Moviat, M.; Boogaard, M. van den; Intven, F.; Voort, P. van der; Hoeven, H. van der; Pickkers, P.

    2013-01-01

    PURPOSE: This study aimed to describe Stewart parameters in critically ill patients with an apparently normal acid-base state and to determine the incidence of mixed metabolic acid-base disorders in these patients. MATERIALS AND METHODS: We conducted a prospective, observational multicenter study of

  2. Apparently homogeneous but intrinsically intermittent flow of taper-free metallic glass nanopillars

    NARCIS (Netherlands)

    Chen, C. Q.; Pei, Y. T.; De Hosson, J. Th. M.

    2012-01-01

    Taper-free small pillars of a Cu-based metallic glass with aspect ratios of c = 3 and 0.7 were tested in situ. With c = 3, decreasing the diameter D to similar to 120 nm caused the pillars to show apparently homogeneous deformation that was intrinsically accommodated by many coordinating local shear

  3. Presence of European bat lyssavirus RNas in apparently healthy Rousettus aegyptiacus bats

    NARCIS (Netherlands)

    Wellenberg, G.J.; Audry, L.; Ronsholt, L.; Poel, van der W.H.M.; Bruschke, C.J.M.; Bourhy, H.

    2002-01-01

    Apparently healthy Rousettus aegyptiacus bats were randomly chosen from a Dutch colony naturally infected with European bat lyssavirus subgenotype 1a (EBL1a). These bats were euthanised three months after the first evidence of an EBL1a infection in the colony. EBL1a genomic and antigenomic RNAs of t

  4. Apparent-contact-angle model at partial wetting and evaporation: Impact of surface forces

    Science.gov (United States)

    Janeček, V.; Nikolayev, V. S.

    2013-01-01

    This theoretical and numerical study deals with evaporation of a fluid wedge in contact with its pure vapor. The model describes a regime where the continuous wetting film is absent and the actual line of the triple gas-liquid-solid contact appears. A constant temperature higher than the saturation temperature is imposed at the solid substrate. The fluid flow is solved in the lubrication approximation. The introduction of the surface forces in the case of the partial wetting is discussed. The apparent contact angle (the gas-liquid interface slope far from the contact line) is studied numerically as a function of the substrate superheating, contact line velocity, and parameters related to the solid-fluid interaction (Young and microscopic contact angles, Hamaker constant, etc.). The dependence of the apparent contact angle on the substrate temperature is in agreement with existing approaches. For water, the apparent contact angle may be 20∘ larger than the Young contact angle for 1 K superheating. The effect of the surface forces on the apparent contact angle is found to be weak.

  5. Thermodynamics of Apparent Horizon and Friedmann Equations in Big Bounce Universe

    CERN Document Server

    Liu, Molin; Lv, Jianbo; Xu, Lixin

    2014-01-01

    In this paper, the thermodynamics of apparent horizon and Friedmann equations are studied in a big bounce universe typified by a non-singular big bounce, as opposed to a singular big bang. This cosmological model can describe radiation dominated early universe and matter dominated late universe in FRW model. Our calculational results show that Einstein gravitational field equations could be derived by the first law of thermodynamics and the fluid's continuity equation. The connections between thermodynamics and gravity are observed in big bounce universe. In the late stages of cold and hot universes, the apparent horizons are convergent and the time when apparent horizons begin to bounce essentially in agreement with that of universe's scalar factor. In the early stage of both cold and hot universes, we find there is only one geometry containing a 4D de Sitter universe with general state parameter. Furthermore, we also find the form of apparent horizon in early universe is strongly dependent on the extra dime...

  6. The reductive decomposition of calcium sulphate I. Kinetics of the apparent solid-solid reaction

    NARCIS (Netherlands)

    Kamphuis, B.; Potma, A.W.; Prins, W.; Swaaij, van W.P.M.

    1992-01-01

    The reductive decomposition of calcium sulphate by hydrogen is used for the regeneration of calcium-based atmospheric fluidized bed combustion (AFBC) SO2 sorbents. The apparent solid¿solid reaction between CaS and CaSO4, one of the steps involved in the reaction mechanism of the reductive decomposit

  7. The apparent influence of climatic change on recent changes of range by European insects (Lepidoptera, Orthoptera)

    NARCIS (Netherlands)

    Burton, J.F.

    2003-01-01

    The apparent influence of climatic change on recent changes of range by European insects (Lepidoptera, Orthoptera) For several years I have been collecting data concerning changes in the ranges of European insects, especially Lepidoptera and Orthoptera. The vast majority of those species which have

  8. Potatoes and risk of obesity, type 2 diabetes, and cardiovascular disease in apparently healthy adults

    DEFF Research Database (Denmark)

    Borch, Daniel; Juul-Hindsgaul, Nicole; Veller, Mette;

    2016-01-01

    , and CVD in apparently healthy adults. DESIGN: MEDLINE, Embase, the Web of Science, and the Cochrane Central Register of Controlled Trials were searched for intervention and prospective observational studies that investigated adults without any known illnesses at baseline, recorded intake of potatoes...

  9. Bacteriophage T4 genes sp and 40 apparently are the same.

    OpenAIRE

    Obringer, J; McCreary, P.; Bernstein, H

    1988-01-01

    The bacteriophage T4 spackle gene, which maintains host membrane integrity, mapped at the same position as gene 40 (head morphogenesis). The cloned spackle gene complemented and cross-reactivated a gene 40 mutant. Like the spackle mutant, gene 40 mutants were defective in genetic exclusion. Apparently, genes spackle and 40 are the same gene.

  10. Uranium-lead isotope systematics and apparent ages of zircons and other minerals in precambrian granitic rocks, Granite Mountains, Wyoming

    Science.gov (United States)

    Ludwig, K. R.; Stuckless, J.S.

    1978-01-01

    Zircon suites from the two main types of granite in the Granite Mountains, Wyoming, yielded concordia-intercept ages of 2,640??20 m.y. for a red, foliated granite (granite of Long Creek Mountain) and 2,595??40 m.y. for the much larger mass of the granite of Lankin Dome. These ages are statistically distinct (40??20 m.y. difference) and are consistent with observed chemical and textural differences. The lower intercepts of the zircon chords of 50??40 and 100+ 75 m.y. for the granite of Long Creek Mountain and granite of Lankin Dome, respectively, are not consistent with reasonable continuous diffusion lead-loss curves but do correspond well with the known (Laramide) time of uplift of the rocks. Epidote, zircon, and apatite from silicified and epidotized zones in the granites all record at least one postcrystallization disturbance in addition to the Laramide event and do not define a unique age of silicification and epidotization. The lower limit of ???2,500 m.y. provided by the least disturbed epidote, however, suggests that these rocks were probably formed by deuteric processes shortly after emplacement of the granite of the Lankin Dome. The earlier of the two disturbances that affected the minerals of the silicified-epidotized rock can be bracketed between 1,350 and 2,240 m.y. ago and is probably the same event that lowered mineral K-Ar and ages in the region. Zircon suites from both types of granite show well-defined linear correlations among U content, common-Pb content, and degree of discordance. One of the zircon suites has an extremely high common-Pb content (up to 180 ppm) and exhibits a component of radiogenic-Pb loss that is apparently unrelated to radiation damage. ?? 1978 Springer-Verlag.

  11. Evaluating apparent competition in limiting the recovery of an endangered ungulate.

    Science.gov (United States)

    Johnson, Heather E; Hebblewhite, Mark; Stephenson, Thomas R; German, David W; Pierce, Becky M; Bleich, Vernon C

    2013-01-01

    Predation can disproportionately affect endangered prey populations when generalist predators are numerically linked to more abundant primary prey. Apparent competition, the term for this phenomenon, has been increasingly implicated in the declines of endangered prey populations. We examined the potential for apparent competition to limit the recovery of Sierra Nevada bighorn sheep (Ovis canadensis sierrae), an endangered subspecies under the US Endangered Species Act. Using a combination of location, demographic, and habitat data, we assessed whether cougar (Puma concolor) predation on endangered bighorn sheep was a consequence of their winter range overlap with abundant mule deer (Odocoileus hemionus). Consistent with the apparent competition hypothesis, bighorn sheep populations with higher spatial overlap with deer exhibited higher rates of cougar predation which had additive effects on adult survival. Bighorn sheep killed by cougars were primarily located within deer winter ranges, even though those areas constituted only a portion of the bighorn sheep winter ranges. We suspect that variation in sympatry between bighorn sheep and deer populations was largely driven by differences in habitat selection among bighorn sheep herds. Indeed, bighorn sheep herds that experienced the highest rates of predation and the greatest spatial overlap with deer also exhibited the strongest selection for low elevation habitat. Although predator-mediated apparent competition may limit some populations of bighorn sheep, it is not the primary factor limiting all populations, suggesting that the dynamics of different herds are highly idiosyncratic. Management plans for endangered species should consider the spatial distributions of key competitors and predators to reduce the potential for apparent competition to hijack conservation success. PMID:22791131

  12. The apparent solubility of aluminum (III) in Hanford high-level waste

    Energy Technology Data Exchange (ETDEWEB)

    Reynolds, Jacob G.

    2012-12-01

    The solubility of aluminum in Hanford nuclear waste impacts on the process ability of the waste by a number of proposed treatment options. For many years, Hanford staff has anecdotally noted that aluminum appears to be considerably more soluble in Hanford waste than the simpler electrolyte solutions used as analogues. There has been minimal scientific study to confirm these anecdotal observations, however. The present study determines the apparent solubility product for gibbsite in 50 tank samples. The ratio of hydroxide to aluminum in the liquid phase for the samples is calculated and plotted as a function of total sodium molarity. Total sodium molarity is used as a surrogate for ionic strength, because the relative ratios of mono, di and trivalent anions are not available for all of the samples. These results were compared to the simple NaOH-NaAl(OH{sub 4})H{sub 2}O system, and the NaOH-NaAl(OH{sub 4})NaCl-H{sub 2}O system data retrieved from the literature. The results show that gibbsite is apparently more soluble in the samples than in the simple systems whenever the sodium molarity is greater than two. This apparent enhanced solubility cannot be explained solely by differences in ionic strength. The change in solubility with ionic strength in simple systems is small compared to the difference between aluminum solubility in Hanford waste and the simple systems. The reason for the apparent enhanced solubility is unknown, but could include. kinetic or thermodynamic factors that are not present in the simple electrolyte systems. Any kinetic explanation would have to explain why the samples are always supersaturated whenever the sodium molarity is above two. Real waste characterization data should not be used to validate thermodynamic solubility models until it can be confirmed that the apparent enhanced gibbsite solubility is a thermodynamic effect and not a kinetic effect.

  13. Effect of increased methionine level on performance and apparent ileal digestibility of amino acids in ducks.

    Science.gov (United States)

    Jamroz, D; Wiliczkiewicz, A; Lemme, A; Orda, J; Skorupińska, J; Wertelecki, T

    2009-10-01

    The experiment was conducted with 960 one-day-old ducklings fed mixtures (I control - 0.28% methionine) additionally supplemented with DL-methionine (DL-Met) at amounts: 0.03% (group II), 0.07% (III), 0.12% (IV) and 0.18% (V). The performance, carcass quality and apparent ileal digestibility of amino acids as the criterions of methionine (Met) effectivity were considered. The analysis of growth and development of ducks as an effect of diversified DL-Met supplements indicate that increased content of this amino acid in the diets has not affected clearly the performance parameters. The body weight of 21-day-old ducklings was significantly affected only by the level of 0.12% of added Met in comparison to control group. On day 42, the differences among groups were negligible; only the addition of 0.12% DL-Met has increased the body weight by 2.4% when compared with control (p > 0.05). Feed conversion estimated for a period of 1-42 days has not been influenced by Met supplementation. The indistinct, however, visible tendency of better ileal amino acids' apparent digestibility (for Asp.a.,Thr, Ser, Glu, Lys) was noted in the groups fed supplemented diets. Application of 0.07% and 0.18% of DL-met, has significantly (p < 0.05) improved the coefficient of cysteine (Cys) apparent ileal digestibility; however, the improvement of Met apparent ileal digestibility has been achieved by the addition of 0.18% Met. The mortality of ducklings in the experiment was very low and varied between 3.15% (II) and 0.0% (groups I and III). In general, application of 0.12% of DL-Met to mixture containing 0.28% Met had positive effect on the productive output of birds and also improved the apparent ileal digestibility of Cys and Met.

  14. The apparent solubility of aluminum (III) in Hanford high-level waste.

    Science.gov (United States)

    Reynolds, Jacob G

    2012-01-01

    The solubility of aluminum in Hanford nuclear waste impacts on the processability of the waste by a number of proposed treatment options. For many years, Hanford staff has anecdotally noted that aluminum appears to be considerably more soluble in Hanford waste than the simpler electrolyte solutions used as analogues. There has been minimal scientific study to confirm these anecdotal observations, however. The present study determines the apparent solubility product for gibbsite in 50 tank samples. The ratio of hydroxide to aluminum in the liquid phase for the samples is calculated and plotted as a function of total sodium molarity. Total sodium molarity is used as a surrogate for ionic strength, because the relative ratios of mono-, di- and trivalent anions are not available for all of the samples. These results were compared to the simple NaOH-NaAl(OH)(4)-H(2)O system, and the NaOH-NaAl(OH)(4)-NaCl-H(2)O system data retrieved from the literature. The results show that gibbsite is apparently more soluble in the samples than in the simple systems whenever the sodium molarity is greater than 2M. This apparent enhanced solubility cannot be explained solely by differences in ionic strength. The change in solubility with ionic strength in simple systems is small compared to the difference between aluminum solubility in Hanford waste and the simple systems. The reason for the apparent enhanced solubility is unknown, but could include kinetic or thermodynamic factors that are not present in the simple electrolyte systems. Any kinetic explanation would have to explain why the samples are always supersaturated whenever the sodium molarity is above 2M. Real waste characterization data should not be used to validate thermodynamic solubility models until it can be confirmed that the apparent enhanced gibbsite solubility is a thermodynamic effect and not a kinetic effect. PMID:22934992

  15. Event boundaries and anaphoric reference.

    Science.gov (United States)

    Thompson, Alexis N; Radvansky, Gabriel A

    2016-06-01

    The current study explored the finding that parsing a narrative into separate events impairs anaphor resolution. According to the Event Horizon Model, when a narrative event boundary is encountered, a new event model is created. Information associated with the prior event model is removed from working memory. So long as the event model containing the anaphor referent is currently being processed, this information should still be available when there is no narrative event boundary, even if reading has been disrupted by a working-memory-clearing distractor task. In those cases, readers may reactivate their prior event model, and anaphor resolution would not be affected. Alternatively, comprehension may not be as event oriented as this account suggests. Instead, any disruption of the contents of working memory during comprehension, event related or not, may be sufficient to disrupt anaphor resolution. In this case, reading comprehension would be more strongly guided by other, more basic language processing mechanisms and the event structure of the described events would play a more minor role. In the current experiments, participants were given stories to read in which we included, between the anaphor and its referent, either the presence of a narrative event boundary (Experiment 1) or a narrative event boundary along with a working-memory-clearing distractor task (Experiment 2). The results showed that anaphor resolution was affected by narrative event boundaries but not by a working-memory-clearing distractor task. This is interpreted as being consistent with the Event Horizon Model of event cognition. PMID:26452376

  16. Event-by-event fluctuations in collective quantities

    OpenAIRE

    S.A. Voloshin; Koch, V; Ritter, H. G.

    1999-01-01

    We discuss an event-by-event fluctuation analysis of particle production in heavy ion collisions. We compare different approaches to the evaluation of the event-by-event dynamical fluctuations in quantities defined on groups of particles, such quantities as mean transverse momentum, transverse momentum spectra slope, strength of anisotropic flow, etc.. The direct computation of the dynamical fluctuations and the sub-event method are discussed in more detail. We also show how the fluctuation i...

  17. Using Event Studies to Assess the Impact of Unexpected Events

    OpenAIRE

    James V Koch; Robert N Fenili

    2013-01-01

    The quantitative assessment of the financial impact of unexpected events is the realm of the “event study.” We examine how CEOs, boards, and public policymakers can utilize event studies to inform and improve their decision making. The breadth of application of event studies is surprisingly broad and ranges from situations involving the death of a CEO to emergency product recalls. We present illustrative event studies for two Steve Jobs-related announcements concerning his health in order to ...

  18. Event Index — an LHCb Event Search System

    Science.gov (United States)

    Ustyuzhanin, A.; Artemov, A.; Kazeev, N.; Redkin, A.

    2015-12-01

    During LHC Run 1, the LHCb experiment recorded around 1011 collision events. This paper describes Event Index — an event search system. Its primary function is to quickly select subsets of events from a combination of conditions, such as the estimated decay channel or number of hits in a subdetector. Event Index is essentially Apache Lucene [1] optimized for read-only indexes distributed over independent shards on independent nodes.

  19. Theoretical analysis for the apparent discrepancy between pbarp and pp data in charged particle forward-backward multiplicity correlations

    CERN Document Server

    Yan, Yu-Liang; Zhou, Dai-Mei; Li, Xiao-Mei; Sa, Ben-Hao

    2008-01-01

    The strength of charged particle forward-backward multiplicity correlation in pbar+p and p+p collisions at s^1/2 = 200 GeV is studied by PYTHIA 6.4 and compared to the UA5 and STAR data correspondingly. It is turned out that a factor of 3-4 apparent discrepancy between UA5 and STAR data can be attributed to the differences in detector acceptances and observing bin interval in both experiments. A mixed event method is introduced and used to calculate the statistical correlation strength and the dynamical correlation strengths stemming from the charge conservation, four- momentum conservation, and decay, respectively. It seems that the statistical correlation is much larger than dynamical one and the charge conservation, four-momentum conservation and decay may account for most part of the dynamical correlation. In addition, we have also calculated the correlation strength by fitting the charged particle multiplicity distribution from PYTHIA to the Negative Binomial Distribution and found that the result agrees...

  20. Single event mass spectrometry

    Science.gov (United States)

    Conzemius, Robert J.

    1990-01-16

    A means and method for single event time of flight mass spectrometry for analysis of specimen materials. The method of the invention includes pulsing an ion source imposing at least one pulsed ion onto the specimen to produce a corresponding emission of at least one electrically charged particle. The emitted particle is then dissociated into a charged ion component and an uncharged neutral component. The ion and neutral components are then detected. The time of flight of the components are recorded and can be used to analyze the predecessor of the components, and therefore the specimen material. When more than one ion particle is emitted from the specimen per single ion impact, the single event time of flight mass spectrometer described here furnis This invention was made with Government support under Contract No. W-7405-ENG82 awarded by the Department of Energy. The Government has certain rights in the invention.