WorldWideScience

Sample records for api based desktop

  1. multiplierz: an extensible API based desktop environment for proteomics data analysis.

    Science.gov (United States)

    Parikh, Jignesh R; Askenazi, Manor; Ficarro, Scott B; Cashorali, Tanya; Webber, James T; Blank, Nathaniel C; Zhang, Yi; Marto, Jarrod A

    2009-10-29

    Efficient analysis of results from mass spectrometry-based proteomics experiments requires access to disparate data types, including native mass spectrometry files, output from algorithms that assign peptide sequence to MS/MS spectra, and annotation for proteins and pathways from various database sources. Moreover, proteomics technologies and experimental methods are not yet standardized; hence a high degree of flexibility is necessary for efficient support of high- and low-throughput data analytic tasks. Development of a desktop environment that is sufficiently robust for deployment in data analytic pipelines, and simultaneously supports customization for programmers and non-programmers alike, has proven to be a significant challenge. We describe multiplierz, a flexible and open-source desktop environment for comprehensive proteomics data analysis. We use this framework to expose a prototype version of our recently proposed common API (mzAPI) designed for direct access to proprietary mass spectrometry files. In addition to routine data analytic tasks, multiplierz supports generation of information rich, portable spreadsheet-based reports. Moreover, multiplierz is designed around a "zero infrastructure" philosophy, meaning that it can be deployed by end users with little or no system administration support. Finally, access to multiplierz functionality is provided via high-level Python scripts, resulting in a fully extensible data analytic environment for rapid development of custom algorithms and deployment of high-throughput data pipelines. Collectively, mzAPI and multiplierz facilitate a wide range of data analysis tasks, spanning technology development to biological annotation, for mass spectrometry-based proteomics research.

  2. multiplierz: an extensible API based desktop environment for proteomics data analysis

    Directory of Open Access Journals (Sweden)

    Webber James T

    2009-10-01

    Full Text Available Abstract Background Efficient analysis of results from mass spectrometry-based proteomics experiments requires access to disparate data types, including native mass spectrometry files, output from algorithms that assign peptide sequence to MS/MS spectra, and annotation for proteins and pathways from various database sources. Moreover, proteomics technologies and experimental methods are not yet standardized; hence a high degree of flexibility is necessary for efficient support of high- and low-throughput data analytic tasks. Development of a desktop environment that is sufficiently robust for deployment in data analytic pipelines, and simultaneously supports customization for programmers and non-programmers alike, has proven to be a significant challenge. Results We describe multiplierz, a flexible and open-source desktop environment for comprehensive proteomics data analysis. We use this framework to expose a prototype version of our recently proposed common API (mzAPI designed for direct access to proprietary mass spectrometry files. In addition to routine data analytic tasks, multiplierz supports generation of information rich, portable spreadsheet-based reports. Moreover, multiplierz is designed around a "zero infrastructure" philosophy, meaning that it can be deployed by end users with little or no system administration support. Finally, access to multiplierz functionality is provided via high-level Python scripts, resulting in a fully extensible data analytic environment for rapid development of custom algorithms and deployment of high-throughput data pipelines. Conclusion Collectively, mzAPI and multiplierz facilitate a wide range of data analysis tasks, spanning technology development to biological annotation, for mass spectrometry-based proteomics research.

  3. Restful API Architecture Based on Laravel Framework

    Science.gov (United States)

    Chen, Xianjun; Ji, Zhoupeng; Fan, Yu; Zhan, Yongsong

    2017-10-01

    Web service has been an industry standard tech for message communication and integration between heterogeneous systems. RESTFUL API has become mainstream web service development paradigm after SOAP, how to effectively construct RESTFUL API remains a research hotspots. This paper presents a development model of RESTFUL API construction based on PHP language and LARAVEL framework. The key technical problems that need to be solved during the construction of RESTFUL API are discussed, and implementation details based on LARAVEL are given.

  4. APIs

    CERN Document Server

    Jacobson, Daniel; Woods, Dan

    2011-01-01

    Programmers used to be the only people excited about APIs, but now a growing number of companies see them as a hot new product channel. This concise guide describes the tremendous business potential of APIs, and demonstrates how you can use them to provide valuable services to clients, partners, or the public via the Internet. You'll learn all the steps necessary for building a cohesive API business strategy from experts in the trenches. Facebook and Twitter APIs continue to be extremely successful, and many other companies find that API demand greatly exceeds website traffic. This book offe

  5. Efficient Sustainable Operation Mechanism of Distributed Desktop Integration Storage Based on Virtualization with Ubiquitous Computing

    Directory of Open Access Journals (Sweden)

    Hyun-Woo Kim

    2015-06-01

    Full Text Available Following the rapid growth of ubiquitous computing, many jobs that were previously manual have now been automated. This automation has increased the amount of time available for leisure; diverse services are now being developed for this leisure time. In addition, the development of small and portable devices like smartphones, diverse Internet services can be used regardless of time and place. Studies regarding diverse virtualization are currently in progress. These studies aim to determine ways to efficiently store and process the big data generated by the multitude of devices and services in use. One topic of such studies is desktop storage virtualization, which integrates distributed desktop resources and provides these resources to users to integrate into distributed legacy desktops via virtualization. In the case of desktop storage virtualization, high availability of virtualization is necessary and important for providing reliability to users. Studies regarding hierarchical structures and resource integration are currently in progress. These studies aim to create efficient data distribution and storage for distributed desktops based on resource integration environments. However, studies regarding efficient responses to server faults occurring in desktop-based resource integration environments have been insufficient. This paper proposes a mechanism for the sustainable operation of desktop storage (SODS for high operational availability. It allows for the easy addition and removal of desktops in desktop-based integration environments. It also activates alternative servers when a fault occurs within a system.

  6. Yoink: An interaction-based partitioning API.

    Science.gov (United States)

    Zheng, Min; Waller, Mark P

    2018-05-15

    Herein, we describe the implementation details of our interaction-based partitioning API (application programming interface) called Yoink for QM/MM modeling and fragment-based quantum chemistry studies. Interactions are detected by computing density descriptors such as reduced density gradient, density overlap regions indicator, and single exponential decay detector. Only molecules having an interaction with a user-definable QM core are added to the QM region of a hybrid QM/MM calculation. Moreover, a set of molecule pairs having density-based interactions within a molecular system can be computed in Yoink, and an interaction graph can then be constructed. Standard graph clustering methods can then be applied to construct fragments for further quantum chemical calculations. The Yoink API is licensed under Apache 2.0 and can be accessed via yoink.wallerlab.org. © 2018 Wiley Periodicals, Inc. © 2018 Wiley Periodicals, Inc.

  7. Improving "tail" computations in a BOINC-based Desktop Grid

    Science.gov (United States)

    Kolokoltsev, Yevgeniy; Ivashko, Evgeny; Gershenson, Carlos

    2017-12-01

    A regular Desktop Grid bag-of-tasks project can take a lot of time to complete computations. An important part of the process is tail computations: when the number of tasks to perform becomes less than the number of computing nodes. At this stage, a dynamic replication could be used to reduce the time needed to complete computations. In this paper, we propose a mathematical model and a strategy of dynamic replication at the tail stage. The results of the numerical experiments are given.

  8. Research and implementation of a Web-based remote desktop image monitoring system

    International Nuclear Information System (INIS)

    Ren Weijuan; Li Luofeng; Wang Chunhong

    2010-01-01

    It studied and implemented an ISS (Image Snapshot Server) system based on Web, using Java Web technology. The ISS system consisted of client web browser and server. The server part could be divided into three modules as the screen shots software, web server and Oracle database. Screen shots software intercepted the desktop environment of the remote monitored PC and sent these pictures to a Tomcat web server for displaying on the web at real time. At the same time, these pictures were also saved in an Oracle database. Through the web browser, monitor person can view the real-time and historical desktop pictures of the monitored PC during some period. It is very convenient for any user to monitor the desktop image of remote monitoring PC. (authors)

  9. EyeScreen: A Vision-Based Desktop Interaction System

    OpenAIRE

    Xu, Yihua; Lv, Jingjun; Li, Shanqing; Jia, Yunde

    2007-01-01

    EyeScreen provides a natural HCI interface with vision-based hand tracking and gesture recognition techniques. Multi-view video images captured from two cameras facing a computer screen are used to track and recognize finger and hand motions. Finger tracking is achieved by skin color detection and particle filtering, and is greatly enhanced by the proposed screen background subtraction method that removes the screen images in advance. Finger click on the screen can also be detected from multi...

  10. Semantic Desktop

    Science.gov (United States)

    Sauermann, Leo; Kiesel, Malte; Schumacher, Kinga; Bernardi, Ansgar

    In diesem Beitrag wird gezeigt, wie der Arbeitsplatz der Zukunft aussehen könnte und wo das Semantic Web neue Möglichkeiten eröffnet. Dazu werden Ansätze aus dem Bereich Semantic Web, Knowledge Representation, Desktop-Anwendungen und Visualisierung vorgestellt, die es uns ermöglichen, die bestehenden Daten eines Benutzers neu zu interpretieren und zu verwenden. Dabei bringt die Kombination von Semantic Web und Desktop Computern besondere Vorteile - ein Paradigma, das unter dem Titel Semantic Desktop bekannt ist. Die beschriebenen Möglichkeiten der Applikationsintegration sind aber nicht auf den Desktop beschränkt, sondern können genauso in Web-Anwendungen Verwendung finden.

  11. Virtualisation Devices for Student Learning: Comparison between Desktop-Based (Oculus Rift) and Mobile-Based (Gear VR) Virtual Reality in Medical and Health Science Education

    Science.gov (United States)

    Moro, Christian; Stromberga, Zane; Stirling, Allan

    2017-01-01

    Consumer-grade virtual reality has recently become available for both desktop and mobile platforms and may redefine the way that students learn. However, the decision regarding which device to utilise within a curriculum is unclear. Desktop-based VR has considerably higher setup costs involved, whereas mobile-based VR cannot produce the quality of…

  12. Desktop Genetics.

    Science.gov (United States)

    Hough, Soren H; Ajetunmobi, Ayokunmi; Brody, Leigh; Humphryes-Kirilov, Neil; Perello, Edward

    2016-11-01

    Desktop Genetics is a bioinformatics company building a gene-editing platform for personalized medicine. The company works with scientists around the world to design and execute state-of-the-art clustered regularly interspaced short palindromic repeats (CRISPR) experiments. Desktop Genetics feeds the lessons learned about experimental intent, single-guide RNA design and data from international genomics projects into a novel CRISPR artificial intelligence system. We believe that machine learning techniques can transform this information into a cognitive therapeutic development tool that will revolutionize medicine.

  13. CLOUD-BASED VS DESKTOP-BASED PROPERTY MANAGEMENT SYSTEMS IN HOTEL

    Directory of Open Access Journals (Sweden)

    Mustafa\tGULMEZ

    2015-06-01

    Full Text Available Even though keeping up with the modern developments in IT sector is crucial for the success and competitiveness of a hotel, it is usually very hard for new technologies to be accepted and implemented. This is the case with the cloud technology for which the opinions between hoteliers are divided on those who think that it is just another fashion trend, unnecessary to be taken into consideration and those that believe that it helps in performing daily operations more easily, leaving space for more interaction with guests both in virtual and real world. Usage of cloud technology in hotels is still in its beginning phase and hoteliers still have to learn more about its advantages and adequate usage for the benefit of overall hotel operating. On the example of hotel property management system (PMS and comparison between features of its older desktop-version and new web-based programs, this research aims at finding out at which stage and how effective is usage of cloud technology in hotels. For this, qualitative research with semi-structured interviews with hotel mangers that use one of these programs was conducted. Reasons for usage and advantages of each version are discussed.

  14. The simulation of CAMAC system based on Windows API

    International Nuclear Information System (INIS)

    Li Lei; Song Yushou; Xi Yinyin; Yan Qiang; Liu Huilan; Li Taosheng

    2012-01-01

    Based on Windows API, a kind of design method to simulate the CAMAC System, which is commonly used in nuclear physics experiments, is developed. Using C++ object-oriented programming, the simulation is carried out in the environment of Visual Studio 2010 and the interfaces, the data-way, the control commands and the modules are simulated with the functions either user-defined or from Windows API. Applying this method, the amplifier plug AMP575A produced by ORTEC is simulated and performance experiments are studied for this simulation module. The results indicate that the simulation module can fulfill the function of pole-zero adjustment, which means this method is competent for the simulation of CAMAC System. Compared with the simulation based on LabVIEW, this way is more flexible and closer to the bottom of the system. All the works above have found a path to making the virtual instrument platform based on CAMAC system. (authors)

  15. Desktop-Virtualisierung

    Science.gov (United States)

    von Liebisch, Daniel

    Thema dieses Artikels sind die Desktop-Virtualisierung, die Vorteile für das Management von Desktops und Citrix XenDesktop als komplette Lösung für die Desktop-Virtualisierung. Folgende Aspekte werden betrachtet: Die Herausforderungen des Desktop-Managements in Umgebungen ohne Desktop-Virtualisierung

  16. Economic analysis of cloud-based desktop virtualization implementation at a hospital.

    Science.gov (United States)

    Yoo, Sooyoung; Kim, Seok; Kim, Taeki; Baek, Rong-Min; Suh, Chang Suk; Chung, Chin Youb; Hwang, Hee

    2012-10-30

    Cloud-based desktop virtualization infrastructure (VDI) is known as providing simplified management of application and desktop, efficient management of physical resources, and rapid service deployment, as well as connection to the computer environment at anytime, anywhere with any device. However, the economic validity of investing in the adoption of the system at a hospital has not been established. This study computed the actual investment cost of the hospital-wide VDI implementation at the 910-bed Seoul National University Bundang Hospital in Korea and the resulting effects (i.e., reductions in PC errors and difficulties, application and operating system update time, and account management time). Return on investment (ROI), net present value (NPV), and internal rate of return (IRR) indexes used for corporate investment decision-making were used for the economic analysis of VDI implementation. The results of five-year cost-benefit analysis given for 400 Virtual Machines (VMs; i.e., 1,100 users in the case of SNUBH) showed that the break-even point was reached in the fourth year of the investment. At that point, the ROI was 122.6%, the NPV was approximately US$192,000, and the IRR showed an investment validity of 10.8%. From our sensitivity analysis to changing the number of VMs (in terms of number of users), the greater the number of adopted VMs was the more investable the system was. This study confirms that the emerging VDI can have an economic impact on hospital information system (HIS) operation and utilization in a tertiary hospital setting.

  17. Economic analysis of cloud-based desktop virtualization implementation at a hospital

    Directory of Open Access Journals (Sweden)

    Yoo Sooyoung

    2012-10-01

    Full Text Available Abstract Background Cloud-based desktop virtualization infrastructure (VDI is known as providing simplified management of application and desktop, efficient management of physical resources, and rapid service deployment, as well as connection to the computer environment at anytime, anywhere with anydevice. However, the economic validity of investing in the adoption of the system at a hospital has not been established. Methods This study computed the actual investment cost of the hospital-wide VDI implementation at the 910-bed Seoul National University Bundang Hospital in Korea and the resulting effects (i.e., reductions in PC errors and difficulties, application and operating system update time, and account management time. Return on investment (ROI, net present value (NPV, and internal rate of return (IRR indexes used for corporate investment decision-making were used for the economic analysis of VDI implementation. Results The results of five-year cost-benefit analysis given for 400 Virtual Machines (VMs; i.e., 1,100 users in the case of SNUBH showed that the break-even point was reached in the fourth year of the investment. At that point, the ROI was 122.6%, the NPV was approximately US$192,000, and the IRR showed an investment validity of 10.8%. From our sensitivity analysis to changing the number of VMs (in terms of number of users, the greater the number of adopted VMs was the more investable the system was. Conclusions This study confirms that the emerging VDI can have an economic impact on hospital information system (HIS operation and utilization in a tertiary hospital setting.

  18. Efficiency Sustainability Resource Visual Simulator for Clustered Desktop Virtualization Based on Cloud Infrastructure

    Directory of Open Access Journals (Sweden)

    Jong Hyuk Park

    2014-11-01

    Full Text Available Following IT innovations, manual operations have been automated, improving the overall quality of life. This has been possible because an organic topology has been formed among many diverse smart devices grafted onto real life. To provide services to these smart devices, enterprises or users use the cloud. Cloud services are divided into infrastructure as a service (IaaS, platform as a service (PaaS and software as a service (SaaS. SaaS is operated on PaaS, and PaaS is operated on IaaS. Since IaaS is the foundation of all services, algorithms for the efficient operation of virtualized resources are required. Among these algorithms, desktop resource virtualization is used for high resource availability when existing desktop PCs are unavailable. For this high resource availability, clustering for hierarchical structures is important. In addition, since many clustering algorithms show different percentages of the main resources depending on the desktop PC distribution rates and environments, selecting appropriate algorithms is very important. If diverse attempts are made to find algorithms suitable for the operating environments’ desktop resource virtualization, huge costs are incurred for the related power, time and labor. Therefore, in the present paper, a desktop resource virtualization clustering simulator (DRV-CS, a clustering simulator for selecting clusters of desktop virtualization clusters to be maintained sustainably, is proposed. The DRV-CS provides simulations, so that clustering algorithms can be selected and elements can be properly applied in different desktop PC environments through the DRV-CS.

  19. Rural Population Administration Management System Based On RESTful API In Bone District (Sistem Manajemen Administrasi Kependudukan Tingkat Pedesaan Berbasis RESTful API di Kabupaten Bone)

    OpenAIRE

    Rismayani, nfn

    2017-01-01

    Bone district is one of region in South Sulawesi province. There are 27 sub-districts and 374 villages in Bone district. A villages sampled in this study is Barakkae village Lamuru Bone district. The problem in this research is how to make the management system administration at rural level in Bone district and how to apply information technology based on RESTful API on rural administration of Bone district. The technology or method used is the RESTful API, RESTful API is REST (REpresentatio...

  20. A Shellcode Detection Method Based on Full Native API Sequence and Support Vector Machine

    Science.gov (United States)

    Cheng, Yixuan; Fan, Wenqing; Huang, Wei; An, Jing

    2017-09-01

    Dynamic monitoring the behavior of a program is widely used to discriminate between benign program and malware. It is usually based on the dynamic characteristics of a program, such as API call sequence or API call frequency to judge. The key innovation of this paper is to consider the full Native API sequence and use the support vector machine to detect the shellcode. We also use the Markov chain to extract and digitize Native API sequence features. Our experimental results show that the method proposed in this paper has high accuracy and low detection rate.

  1. A Web API ecosystem through feature-based reuse

    NARCIS (Netherlands)

    Verborgh, Ruben; Dumontier, Michel

    2016-01-01

    The current Web API landscape does not scale well: every API requires its own hardcoded clients in an unusually short-lived, tightly coupled relationship of highly subjective quality. This directly leads to inflated development costs, and prevents the design of a more intelligent generation of

  2. Towards Standardized Patient Data Exchange: Integrating a FHIR Based API for the Open Medical Record System.

    Science.gov (United States)

    Kasthurirathne, Suranga N; Mamlin, Burke; Grieve, Grahame; Biondich, Paul

    2015-01-01

    Interoperability is essential to address limitations caused by the ad hoc implementation of clinical information systems and the distributed nature of modern medical care. The HL7 V2 and V3 standards have played a significant role in ensuring interoperability for healthcare. FHIR is a next generation standard created to address fundamental limitations in HL7 V2 and V3. FHIR is particularly relevant to OpenMRS, an Open Source Medical Record System widely used across emerging economies. FHIR has the potential to allow OpenMRS to move away from a bespoke, application specific API to a standards based API. We describe efforts to design and implement a FHIR based API for the OpenMRS platform. Lessons learned from this effort were used to define long term plans to transition from the legacy OpenMRS API to a FHIR based API that greatly reduces the learning curve for developers and helps enhance adhernce to standards.

  3. A SNP based high-density linkage map of Apis cerana reveals a high recombination rate similar to Apis mellifera.

    Science.gov (United States)

    Shi, Yuan Yuan; Sun, Liang Xian; Huang, Zachary Y; Wu, Xiao Bo; Zhu, Yong Qiang; Zheng, Hua Jun; Zeng, Zhi Jiang

    2013-01-01

    The Eastern honey bee, Apis cerana Fabricius, is distributed in southern and eastern Asia, from India and China to Korea and Japan and southeast to the Moluccas. This species is also widely kept for honey production besides Apis mellifera. Apis cerana is also a model organism for studying social behavior, caste determination, mating biology, sexual selection, and host-parasite interactions. Few resources are available for molecular research in this species, and a linkage map was never constructed. A linkage map is a prerequisite for quantitative trait loci mapping and for analyzing genome structure. We used the Chinese honey bee, Apis cerana cerana to construct the first linkage map in the Eastern honey bee. F2 workers (N = 103) were genotyped for 126,990 single nucleotide polymorphisms (SNPs). After filtering low quality and those not passing the Mendel test, we obtained 3,000 SNPs, 1,535 of these were informative and used to construct a linkage map. The preliminary map contains 19 linkage groups, we then mapped the 19 linkage groups to 16 chromosomes by comparing the markers to the genome of A. mellfiera. The final map contains 16 linkage groups with a total of 1,535 markers. The total genetic distance is 3,942.7 centimorgans (cM) with the largest linkage group (180 loci) measuring 574.5 cM. Average marker interval for all markers across the 16 linkage groups is 2.6 cM. We constructed a high density linkage map for A. c. cerana with 1,535 markers. Because the map is based on SNP markers, it will enable easier and faster genotyping assays than randomly amplified polymorphic DNA or microsatellite based maps used in A. mellifera.

  4. A SNP based high-density linkage map of Apis cerana reveals a high recombination rate similar to Apis mellifera.

    Directory of Open Access Journals (Sweden)

    Yuan Yuan Shi

    Full Text Available BACKGROUND: The Eastern honey bee, Apis cerana Fabricius, is distributed in southern and eastern Asia, from India and China to Korea and Japan and southeast to the Moluccas. This species is also widely kept for honey production besides Apis mellifera. Apis cerana is also a model organism for studying social behavior, caste determination, mating biology, sexual selection, and host-parasite interactions. Few resources are available for molecular research in this species, and a linkage map was never constructed. A linkage map is a prerequisite for quantitative trait loci mapping and for analyzing genome structure. We used the Chinese honey bee, Apis cerana cerana to construct the first linkage map in the Eastern honey bee. RESULTS: F2 workers (N = 103 were genotyped for 126,990 single nucleotide polymorphisms (SNPs. After filtering low quality and those not passing the Mendel test, we obtained 3,000 SNPs, 1,535 of these were informative and used to construct a linkage map. The preliminary map contains 19 linkage groups, we then mapped the 19 linkage groups to 16 chromosomes by comparing the markers to the genome of A. mellfiera. The final map contains 16 linkage groups with a total of 1,535 markers. The total genetic distance is 3,942.7 centimorgans (cM with the largest linkage group (180 loci measuring 574.5 cM. Average marker interval for all markers across the 16 linkage groups is 2.6 cM. CONCLUSION: We constructed a high density linkage map for A. c. cerana with 1,535 markers. Because the map is based on SNP markers, it will enable easier and faster genotyping assays than randomly amplified polymorphic DNA or microsatellite based maps used in A. mellifera.

  5. [Teaching Desktop] Video Conferencing in a Collaborative and Problem Based Setting

    DEFF Research Database (Denmark)

    Ørngreen, Rikke; Mouritzen, Per

    2013-01-01

    , teachers and assistant teachers wanted to find ways in the design for learning that enables the learners to acquire knowledge about the theories, models and concepts of the subject, as well as hands‐on competencies in a learning‐by‐doing manner. In particular we address the area of desktop video...... their educational design and their role as teachers in this video conference setting. The students reflect on their experiences and designs in a blog and the group collaboratively hands in a reflection paper online. Both blog posts and reflection papers needs to relate to the literature of the module. Our analysis...

  6. Researching of Covert Timing Channels Based on HTTP Cache Headers in Web API

    Directory of Open Access Journals (Sweden)

    Denis Nikolaevich Kolegov

    2015-12-01

    Full Text Available In this paper, it is shown how covert timing channels based on HTTP cache headers can be implemented using different Web API of Google Drive, Dropbox and Facebook  Internet services.

  7. Nuclear plant analyzer desktop workstation

    International Nuclear Information System (INIS)

    Beelman, R.J.

    1990-01-01

    In 1983 the U.S. Nuclear Regulatory Commission (USNRC) commissioned the Idaho National Engineering Laboratory (INEL) to develop a Nuclear Plant Analyzer (NPA). The NPA was envisioned as a graphical aid to assist reactor safety analysts in comprehending the results of thermal-hydraulic code calculations. The development was to proceed in three distinct phases culminating in a desktop reactor safety workstation. The desktop NPA is now complete. The desktop NPA is a microcomputer based reactor transient simulation, visualization and analysis tool developed at INEL to assist an analyst in evaluating the transient behavior of nuclear power plants by means of graphic displays. The NPA desktop workstation integrates advanced reactor simulation codes with online computer graphics allowing reactor plant transient simulation and graphical presentation of results. The graphics software, written exclusively in ANSI standard C and FORTRAN 77 and implemented over the UNIX/X-windows operating environment, is modular and is designed to interface to the NRC's suite of advanced thermal-hydraulic codes to the extent allowed by that code. Currently, full, interactive, desktop NPA capabilities are realized only with RELAP5

  8. Desktop Virtualization: Applications and Considerations

    Science.gov (United States)

    Hodgman, Matthew R.

    2013-01-01

    As educational technology continues to rapidly become a vital part of a school district's infrastructure, desktop virtualization promises to provide cost-effective and education-enhancing solutions to school-based computer technology problems in school systems locally and abroad. This article outlines the history of and basic concepts behind…

  9. Implementation of news module for news client based on ApiCloud

    Directory of Open Access Journals (Sweden)

    Fu Xin

    2017-01-01

    Full Text Available With the development of new media technology, news client has become the main battlefield of news browsing. Based on the ApiCloud hybrid development platform, this paper uses HTML, JavaScript and other technologies to develop the mobile client news module, and uses WAMP integrated development environment to build a news publishing system on the server side.

  10. Implementation of news module for news client based on ApiCloud

    OpenAIRE

    Fu Xin; Liang Yu; Cao Sanxing; Gu Hongbo

    2017-01-01

    With the development of new media technology, news client has become the main battlefield of news browsing. Based on the ApiCloud hybrid development platform, this paper uses HTML, JavaScript and other technologies to develop the mobile client news module, and uses WAMP integrated development environment to build a news publishing system on the server side.

  11. Desktop grid computing

    CERN Document Server

    Cerin, Christophe

    2012-01-01

    Desktop Grid Computing presents common techniques used in numerous models, algorithms, and tools developed during the last decade to implement desktop grid computing. These techniques enable the solution of many important sub-problems for middleware design, including scheduling, data management, security, load balancing, result certification, and fault tolerance. The book's first part covers the initial ideas and basic concepts of desktop grid computing. The second part explores challenging current and future problems. Each chapter presents the sub-problems, discusses theoretical and practical

  12. Linux Desktop Pocket Guide

    CERN Document Server

    Brickner, David

    2005-01-01

    While Mac OS X garners all the praise from pundits, and Windows XP attracts all the viruses, Linux is quietly being installed on millions of desktops every year. For programmers and system administrators, business users, and educators, desktop Linux is a breath of fresh air and a needed alternative to other operating systems. The Linux Desktop Pocket Guide is your introduction to using Linux on five of the most popular distributions: Fedora, Gentoo, Mandriva, SUSE, and Ubuntu. Despite what you may have heard, using Linux is not all that hard. Firefox and Konqueror can handle all your web bro

  13. HTTP-based Search and Ordering Using ECHO's REST-based and OpenSearch APIs

    Science.gov (United States)

    Baynes, K.; Newman, D. J.; Pilone, D.

    2012-12-01

    Metadata is an important entity in the process of cataloging, discovering, and describing Earth science data. NASA's Earth Observing System (EOS) ClearingHOuse (ECHO) acts as the core metadata repository for EOSDIS data centers, providing a centralized mechanism for metadata and data discovery and retrieval. By supporting both the ESIP's Federated Search API and its own search and ordering interfaces, ECHO provides multiple capabilities that facilitate ease of discovery and access to its ever-increasing holdings. Users are able to search and export metadata in a variety of formats including ISO 19115, json, and ECHO10. This presentation aims to inform technically savvy clients interested in automating search and ordering of ECHO's metadata catalog. The audience will be introduced to practical and applicable examples of end-to-end workflows that demonstrate finding, sub-setting and ordering data that is bound by keyword, temporal and spatial constraints. Interaction with the ESIP OpenSearch Interface will be highlighted, as will ECHO's own REST-based API.

  14. VMware Horizon 6 desktop virtualization solutions

    CERN Document Server

    Cartwright, Ryan; Langone, Jason; Leibovici, Andre

    2014-01-01

    If you are a desktop architect, solution provider, end-user consultant, virtualization engineer, or anyone who wants to learn how to plan and design the implementation of a virtual desktop solution based on Horizon 6, then this book is for you. An understanding of VMware vSphere fundamentals coupled with experience in the installation or administration of a VMware environment would be a plus during reading.

  15. Fatigue monitoring desktop guide

    International Nuclear Information System (INIS)

    Woods, K.; Thomas, K.

    2012-01-01

    The development of a program for managing material aging (MMG) in the nuclear industry requires a new and different perspective. The classical method for MMG is cycle counting, which has been shown to have limited success. The classical method has been successful in satisfying the ductile condition per the America Society of Mechanical Engineers' (ASME) design criteria. However, the defined material failure mechanism has transformed from through-wall cracking and leakage (ASME) to crack initiation (NUREG-6909). This transformation is based on current industry experience with material degradation early in plant life and can be attributed to fabrication issues and environment concerns where cycle counting has been unsuccessful. This new perspective provides a different approach to cycle counting that incorporates all of the information about the material conditions. This approach goes beyond the consideration of a static analysis and includes a dynamic assessment of component health, which is required for operating plants. This health definition should consider fabrication, inspections, transient conditions and industry operating experience. In addition, this collection of information can be transparent to a broader audience that may not have a full understanding of the system design or the potential causes of early material degradation. This paper will present the key points that are needed for a successful fatigue monitoring desktop guide. (authors)

  16. Desktop Computing Integration Project

    Science.gov (United States)

    Tureman, Robert L., Jr.

    1992-01-01

    The Desktop Computing Integration Project for the Human Resources Management Division (HRMD) of LaRC was designed to help division personnel use personal computing resources to perform job tasks. The three goals of the project were to involve HRMD personnel in desktop computing, link mainframe data to desktop capabilities, and to estimate training needs for the division. The project resulted in increased usage of personal computers by Awards specialists, an increased awareness of LaRC resources to help perform tasks, and personal computer output that was used in presentation of information to center personnel. In addition, the necessary skills for HRMD personal computer users were identified. The Awards Office was chosen for the project because of the consistency of their data requests and the desire of employees in that area to use the personal computer.

  17. Increasing Open Source Software Integration on the Department of Defense Unclassified Desktop

    Science.gov (United States)

    2008-06-01

    Figure 3. Windows Remote Desktop from Linux................................................ 49 Figure 4. Citrix XenDesktop Virtualization...released XenDesktop product from Citrix is one such example (Figure 4). 50 Figure 4. Citrix XenDesktop Virtualization Source: http...described in Chapter IV are currently used to satisfy the needs of these COI’s, namely remote desktop computing via terminal servers and Citrix -based

  18. Lung segmentation refinement based on optimal surface finding utilizing a hybrid desktop/virtual reality user interface.

    Science.gov (United States)

    Sun, Shanhui; Sonka, Milan; Beichel, Reinhard R

    2013-01-01

    Recently, the optimal surface finding (OSF) and layered optimal graph image segmentation of multiple objects and surfaces (LOGISMOS) approaches have been reported with applications to medical image segmentation tasks. While providing high levels of performance, these approaches may locally fail in the presence of pathology or other local challenges. Due to the image data variability, finding a suitable cost function that would be applicable to all image locations may not be feasible. This paper presents a new interactive refinement approach for correcting local segmentation errors in the automated OSF-based segmentation. A hybrid desktop/virtual reality user interface was developed for efficient interaction with the segmentations utilizing state-of-the-art stereoscopic visualization technology and advanced interaction techniques. The user interface allows a natural and interactive manipulation of 3-D surfaces. The approach was evaluated on 30 test cases from 18 CT lung datasets, which showed local segmentation errors after employing an automated OSF-based lung segmentation. The performed experiments exhibited significant increase in performance in terms of mean absolute surface distance errors (2.54±0.75 mm prior to refinement vs. 1.11±0.43 mm post-refinement, p≪0.001). Speed of the interactions is one of the most important aspects leading to the acceptance or rejection of the approach by users expecting real-time interaction experience. The average algorithm computing time per refinement iteration was 150 ms, and the average total user interaction time required for reaching complete operator satisfaction was about 2 min per case. This time was mostly spent on human-controlled manipulation of the object to identify whether additional refinement was necessary and to approve the final segmentation result. The reported principle is generally applicable to segmentation problems beyond lung segmentation in CT scans as long as the underlying segmentation utilizes the

  19. Apis - a Digital Inventory of Archaeological Heritage Based on Remote Sensing Data

    Science.gov (United States)

    Doneus, M.; Forwagner, U.; Liem, J.; Sevara, C.

    2017-08-01

    Heritage managers are in need of dynamic spatial inventories of archaeological and cultural heritage that provide them with multipurpose tools to interactively understand information about archaeological heritage within its landscape context. Specifically, linking site information with the respective non-invasive prospection data is of increasing importance as it allows for the assessment of inherent uncertainties related to the use and interpretation of remote sensing data by the educated and knowledgeable heritage manager. APIS, the archaeological prospection information system of the Aerial Archive of the University of Vienna, is specifically designed to meet these needs. It provides storage and easy access to all data concerning aerial photographs and archaeological sites through a single GIS-based application. Furthermore, APIS has been developed in an open source environment, which allows it to be freely distributed and modified. This combination in one single open source system facilitates an easy workflow for data management, interpretation, storage, and retrieval. APIS and a sample dataset will be released free of charge under creative commons license in near future.

  20. Towards SLA-Driven API Gateways

    OpenAIRE

    Gámez Díaz, Antonio; Fernández Montes, Pablo; Ruiz Cortés, Antonio

    2015-01-01

    As APIs are becoming popular to build Service-Based Ap- plications (SBA), API Gateways are being increasingly used to facilitate API features management. They o er API management functionalities such as pricing plans support, user authentication, API versioning or response caching. Some parts of the information that an API Gateway needs are already included into a Service Level Agreement (SLA), that providers use to describe the rights and the obligations of involved par- ...

  1. Generic Black-Box End-to-End Attack Against State of the Art API Call Based Malware Classifiers

    OpenAIRE

    Rosenberg, Ishai; Shabtai, Asaf; Rokach, Lior; Elovici, Yuval

    2017-01-01

    In this paper, we present a black-box attack against API call based machine learning malware classifiers, focusing on generating adversarial sequences combining API calls and static features (e.g., printable strings) that will be misclassified by the classifier without affecting the malware functionality. We show that this attack is effective against many classifiers due to the transferability principle between RNN variants, feed forward DNNs, and traditional machine learning classifiers such...

  2. The major royal jelly proteins 8 and 9 (Api m 11) are glycosylated components of Apis mellifera venom with allergenic potential beyond carbohydrate-based reactivity.

    Science.gov (United States)

    Blank, S; Bantleon, F I; McIntyre, M; Ollert, M; Spillner, E

    2012-06-01

    As hymenoptera venoms are one of the allergen sources causing the highest incidence of anaphylaxis and sometimes fatal consequences, the detailed characterization of all venom allergens is imperative for design of component-resolved diagnostic approaches and improved intervention strategies. Our aim was the immunochemical characterization of major royal jelly proteins (MRJP) 8 and 9, both components identified in honeybee venom (HBV) and putative allergens. Both MRJPs were recombinantly produced as soluble differentially glycosylated proteins providing a defined degree of reactivity to cross-reactive carbohydrate determinants (CCD) in insect cells. Allergen-specific IgE(sIgE) reactivity of HBV-allergic patients was analysed by ELISA and immunoblotting. MRJP8 and MRJP9 were identified as venom components by MS-based proteomic analyses. In a population of 47 HBV-allergic patients, reactivities with CCD-carrying MRJPs were in the range of 56% (61%), underlining the contribution of CCDs to allergen-binding. Beyond CCD-reactivity, 15% of patients showed sIgE reactivity with MRJP8 and 34% with MRJP9 respectively. These reactivities roughly in the range of Api m 2 render the MRJPs minor, but important allergens. The glycosylated MRJP8 and MRJP9 of HBV have IgE-sensitizing potential in HBV-allergic patients beyond CCD reactivity and have to be considered as allergens, which might be potentially important for a fraction of venom allergic patients. They are valuable tools to elucidate individual component-resolved reactivity profiles of venom allergic patients and to provide insights into the role of particular venom components. Due to their allergenic properties, MRJP8 and MRJP9 were designated as isoallergens Api m 11.0101 and Api m 11.0201 respectively. © 2012 Blackwell Publishing Ltd.

  3. Risk analysis of heat recovery steam generator with semi quantitative risk based inspection API 581

    Science.gov (United States)

    Prayogo, Galang Sandy; Haryadi, Gunawan Dwi; Ismail, Rifky; Kim, Seon Jin

    2016-04-01

    Corrosion is a major problem that most often occurs in the power plant. Heat recovery steam generator (HRSG) is an equipment that has a high risk to the power plant. The impact of corrosion damage causing HRSG power plant stops operating. Furthermore, it could be threaten the safety of employees. The Risk Based Inspection (RBI) guidelines by the American Petroleum Institute (API) 58 has been used to risk analysis in the HRSG 1. By using this methodology, the risk that caused by unexpected failure as a function of the probability and consequence of failure can be estimated. This paper presented a case study relating to the risk analysis in the HRSG, starting with a summary of the basic principles and procedures of risk assessment and applying corrosion RBI for process industries. The risk level of each HRSG equipment were analyzed: HP superheater has a medium high risk (4C), HP evaporator has a medium-high risk (4C), and the HP economizer has a medium risk (3C). The results of the risk assessment using semi-quantitative method of standard API 581 based on the existing equipment at medium risk. In the fact, there is no critical problem in the equipment components. Damage mechanisms were prominent throughout the equipment is thinning mechanism. The evaluation of the risk approach was done with the aim of reducing risk by optimizing the risk assessment activities.

  4. Public open space desktop auditing tool

    DEFF Research Database (Denmark)

    Mygind, Lærke; Bentsen, Peter; Badland, Hannah

    2016-01-01

    Features of public open space (POS) have traditionally been described using on-site direct observation, but recently, low-cost and time-efficient remote desktop auditing tools have been developed. We adapted an existing, validated desktop auditing tool (the Public Open Space Desktop Auditing Tool......: POSDAT) and tested it in a pilot sample of regional and metropolitan settings in Victoria, Australia. Using Google Maps and Street View, local government webpages, the National Public Toilet Registry and spatial data, we captured POSDAT items in 171 POS across 17 suburbs, of which 9 were regional. POSDAT...... resolution Google Street View imagery available for some outer regional areas and the inconsistency of detail in information on local government webpages hindered a consistent assessment of POS. Thus, POSDAT, based on the spatial data applied in this study, is appropriate for use in metropolitan...

  5. Corporate Consumer Contact API

    Data.gov (United States)

    General Services Administration — The data in the Corporate Consumer Contact API is based on the content you can find in the Corporate Consumer Contact listing in the Consumer Action Handbook (PDF)....

  6. Lowering the Barriers to Using Data: Enabling Desktop-based HPD Science through Virtual Environments and Web Data Services

    Science.gov (United States)

    Druken, K. A.; Trenham, C. E.; Steer, A.; Evans, B. J. K.; Richards, C. J.; Smillie, J.; Allen, C.; Pringle, S.; Wang, J.; Wyborn, L. A.

    2016-12-01

    The Australian National Computational Infrastructure (NCI) provides access to petascale data in climate, weather, Earth observations, and genomics, and terascale data in astronomy, geophysics, ecology and land use, as well as social sciences. The data is centralized in a closely integrated High Performance Computing (HPC), High Performance Data (HPD) and cloud facility. Despite this, there remain significant barriers for many users to find and access the data: simply hosting a large volume of data is not helpful if researchers are unable to find, access, and use the data for their particular need. Use cases demonstrate we need to support a diverse range of users who are increasingly crossing traditional research discipline boundaries. To support their varying experience, access needs and research workflows, NCI has implemented an integrated data platform providing a range of services that enable users to interact with our data holdings. These services include: - A GeoNetwork catalog built on standardized Data Management Plans to search collection metadata, and find relevant datasets; - Web data services to download or remotely access data via OPeNDAP, WMS, WCS and other protocols; - Virtual Desktop Infrastructure (VDI) built on a highly integrated on-site cloud with access to both the HPC peak machine and research data collections. The VDI is a fully featured environment allowing visualization, code development and analysis to take place in an interactive desktop environment; and - A Learning Management System (LMS) containing User Guides, Use Case examples and Jupyter Notebooks structured into courses, so that users can self-teach how to use these facilities with examples from our system across a range of disciplines. We will briefly present these components, and discuss how we engage with data custodians and consumers to develop standardized data structures and services that support the range of needs. We will also highlight some key developments that have

  7. A web-based remote radiation treatment planning system using the remote desktop function of a computer operating system: a preliminary report.

    Science.gov (United States)

    Suzuki, Keishiro; Hirasawa, Yukinori; Yaegashi, Yuji; Miyamoto, Hideki; Shirato, Hiroki

    2009-01-01

    We developed a web-based, remote radiation treatment planning system which allowed staff at an affiliated hospital to obtain support from a fully staffed central institution. Network security was based on a firewall and a virtual private network (VPN). Client computers were installed at a cancer centre, at a university hospital and at a staff home. We remotely operated the treatment planning computer using the Remote Desktop function built in to the Windows operating system. Except for the initial setup of the VPN router, no special knowledge was needed to operate the remote radiation treatment planning system. There was a time lag that seemed to depend on the volume of data traffic on the Internet, but it did not affect smooth operation. The initial cost and running cost of the system were reasonable.

  8. Comparison of ground based indices (API and AQI) with satellite based aerosol products.

    Science.gov (United States)

    Zheng, Sheng; Cao, Chun-Xiang; Singh, Ramesh P

    2014-08-01

    Air quality in mega cities is one of the major concerns due to serious health issues and its indirect impact to the climate. Among mega cities, Beijing city is considered as one of the densely populated cities with extremely poor air quality. The meteorological parameters (wind, surface temperature, air temperature and relative humidity) control the dynamics and dispersion of air pollution. China National Environmental Monitoring Centre (CNEMC) started air pollution index (API) as of 2000 to evaluate air quality, but over the years, it was felt that the air quality is not well represented by API. Recently, the Ministry of Environmental Protection (MEP) of the People's Republic of China (PRC) started using a new index "air quality index (AQI)" from January 2013. We have compared API and AQI with three different MODIS (MODIS - Moderate Resolution Imaging SpectroRadiometer, onboard the Terra/Aqua satellites) AOD (aerosol optical depth) products for ten months, January-October, 2013. The correlation between AQI and Aqua Deep Blue AOD was found to be reasonably good as compared with API, mainly due to inclusion of PM2.5 in the calculation of AQI. In addition, for every month, the correlation coefficient between AQI and Aqua Deep Blue AOD was found to be relatively higher in the month of February to May. According to the monthly average distribution of precipitation, temperature, and PM10, the air quality in the months of June-September was better as compared to those in the months of February-May. AQI and Aqua Deep Blue AOD show highly polluted days associated with dust event, representing true air quality of Beijing. Copyright © 2013 Elsevier B.V. All rights reserved.

  9. Design and Implement AN Interoperable Internet of Things Application Based on AN Extended Ogc Sensorthings Api Standard

    Science.gov (United States)

    Huang, C. Y.; Wu, C. H.

    2016-06-01

    The Internet of Things (IoT) is an infrastructure that interconnects uniquely-identifiable devices using the Internet. By interconnecting everyday appliances, various monitoring and physical mashup applications can be constructed to improve people's daily life. However, IoT devices created by different manufacturers follow different proprietary protocols and cannot communicate with each other. This heterogeneity issue causes different products to be locked in multiple closed ecosystems that we call IoT silos. In order to address this issue, a common industrial solution is the hub approach, which implements connectors to communicate with IoT devices following different protocols. However, with the growing number of proprietary protocols proposed by device manufacturers, IoT hubs need to support and maintain a lot of customized connectors. Hence, we believe the ultimate solution to address the heterogeneity issue is to follow open and interoperable standard. Among the existing IoT standards, the Open Geospatial Consortium (OGC) SensorThings API standard supports comprehensive conceptual model and query functionalities. The first version of SensorThings API mainly focuses on connecting to IoT devices and sharing sensor observations online, which is the sensing capability. Besides the sensing capability, IoT devices could also be controlled via the Internet, which is the tasking capability. While the tasking capability was not included in the first version of the SensorThings API standard, this research aims on defining the tasking capability profile and integrates with the SensorThings API standard, which we call the extended-SensorThings API in this paper. In general, this research proposes a lightweight JSON-based web service description, the "Tasking Capability Description", allowing device owners and manufacturers to describe different IoT device protocols. Through the extended- SensorThings API, users and applications can follow a coherent protocol to control Io

  10. An interactive physics-based unmanned ground vehicle simulator leveraging open source gaming technology: progress in the development and application of the virtual autonomous navigation environment (VANE) desktop

    Science.gov (United States)

    Rohde, Mitchell M.; Crawford, Justin; Toschlog, Matthew; Iagnemma, Karl D.; Kewlani, Guarav; Cummins, Christopher L.; Jones, Randolph A.; Horner, David A.

    2009-05-01

    It is widely recognized that simulation is pivotal to vehicle development, whether manned or unmanned. There are few dedicated choices, however, for those wishing to perform realistic, end-to-end simulations of unmanned ground vehicles (UGVs). The Virtual Autonomous Navigation Environment (VANE), under development by US Army Engineer Research and Development Center (ERDC), provides such capabilities but utilizes a High Performance Computing (HPC) Computational Testbed (CTB) and is not intended for on-line, real-time performance. A product of the VANE HPC research is a real-time desktop simulation application under development by the authors that provides a portal into the HPC environment as well as interaction with wider-scope semi-automated force simulations (e.g. OneSAF). This VANE desktop application, dubbed the Autonomous Navigation Virtual Environment Laboratory (ANVEL), enables analysis and testing of autonomous vehicle dynamics and terrain/obstacle interaction in real-time with the capability to interact within the HPC constructive geo-environmental CTB for high fidelity sensor evaluations. ANVEL leverages rigorous physics-based vehicle and vehicle-terrain interaction models in conjunction with high-quality, multimedia visualization techniques to form an intuitive, accurate engineering tool. The system provides an adaptable and customizable simulation platform that allows developers a controlled, repeatable testbed for advanced simulations. ANVEL leverages several key technologies not common to traditional engineering simulators, including techniques from the commercial video-game industry. These enable ANVEL to run on inexpensive commercial, off-the-shelf (COTS) hardware. In this paper, the authors describe key aspects of ANVEL and its development, as well as several initial applications of the system.

  11. Recalls API

    Data.gov (United States)

    General Services Administration — This Recalls API allows you to tap into a list of (1) drug and food safety recalls from the Food and Drug Administration, Food Safety and Inspection Service, and...

  12. Jobs API

    Data.gov (United States)

    General Services Administration — This Jobs API returns job openings across the federal government and includes all current openings posted on USAJobs.gov that are open to the public and located in...

  13. Performance indicators for carrier-based DPIs: Carrier surface properties for capsule filling and API properties for in vitro aerosolisation.

    Science.gov (United States)

    Faulhammer, E; Zellnitz, S; Wutscher, T; Stranzinger, S; Zimmer, A; Paudel, A

    2018-01-30

    This study investigates engineered carrier, as well as engineered API particles, and shows that there are distinct performance indicators of particle engineering for carrier-based dry powder inhalers (DPIs). Spray dried (SDSS) and jet-milled (JMSS) salbutamol sulphate (SS) was blended with untreated α-lactose monohydrate (LAC_R) and α-lactose monohydrate engineered (LAC_E). Subsequent capsule filling was performed with different process settings on a dosator nozzle capsule filling machine in order to reach a target fill weight of 20-25 mg. To evaluate the performance of the different mixtures, in vitro lung deposition experiments were carried out with a next generation impactor, the emitted dose (ED) and fine particle fraction (FPF) were calculated based on the specification of the European pharmacopoeia. The FPF of micronised powder blends is significantly higher (20%) compared to the FPF of spray dried blends (5%). Compared to API engineering, carrier engineering had a positive effect on the capsule filling performance (weight variability and mean fill weight) at lower compression ratios (setting 1). Results further showed that higher compression ratios appear to be beneficial in terms of capsule filling performance (higher fill weight and less fill weight variation). Concluding, it can be stated that the carrier engineering, or generally carrier properties, govern downstream processing, whereas the API engineering and API properties govern the aerosolisation performance and thereby significantly affect the dose delivery to the lungs. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Effect of Microstructure on Hydrogen Diffusion in Weld and API X52 Pipeline Steel Base Metals under Cathodic Protection

    Directory of Open Access Journals (Sweden)

    R. C. Souza

    2017-01-01

    Full Text Available The aim of this research was to evaluate the influence of microstructure on hydrogen permeation of weld and API X52 base metal under cathodic protection. The microstructures analyzed were of the API X52, as received, quenched, and annealed, and the welded zone. The test was performed in base metal (BM, quenched base metal (QBM, annealed base metal (ABM, and weld metal (WM. Hydrogen permeation flows were evaluated using electrochemical tests in a Devanathan cell. The potentiodynamic polarization curves were carried out to evaluate the corrosion resistance of each microstructure. All tests were carried out in synthetic soil solutions NS4 and NS4 + sodium thiosulfate at 25°C. The sodium thiosulfate was used to simulate sulfate reduction bacteria (SRB. Through polarization, assays established that the microstructure does not influence the corrosion resistance. The permeation tests showed that weld metal had lower hydrogen flow than base metal as received, quenched, and annealed.

  15. USAJOBS Job Opportunity Announcements (JOA) REST API

    Data.gov (United States)

    Office of Personnel Management — This REST-based API is designed to support lightweight Federal Job Opportunity Announcement (JOA) content consumption by consumers. It is anticipated that this API...

  16. USAJOBS Job Opportunity Announcements (JOA) SOAP API

    Data.gov (United States)

    Office of Personnel Management — The purpose of the SOAP based API is to provide the full Federal Job Opportunity Announcement (JOA) content to the consumer. It is anticipated that this API will be...

  17. An adaptive software defined radio design based on a standard space telecommunication radio system API

    Science.gov (United States)

    Xiong, Wenhao; Tian, Xin; Chen, Genshe; Pham, Khanh; Blasch, Erik

    2017-05-01

    Software defined radio (SDR) has become a popular tool for the implementation and testing for communications performance. The advantage of the SDR approach includes: a re-configurable design, adaptive response to changing conditions, efficient development, and highly versatile implementation. In order to understand the benefits of SDR, the space telecommunication radio system (STRS) was proposed by NASA Glenn research center (GRC) along with the standard application program interface (API) structure. Each component of the system uses a well-defined API to communicate with other components. The benefit of standard API is to relax the platform limitation of each component for addition options. For example, the waveform generating process can support a field programmable gate array (FPGA), personal computer (PC), or an embedded system. As long as the API defines the requirements, the generated waveform selection will work with the complete system. In this paper, we demonstrate the design and development of adaptive SDR following the STRS and standard API protocol. We introduce step by step the SDR testbed system including the controlling graphic user interface (GUI), database, GNU radio hardware control, and universal software radio peripheral (USRP) tranceiving front end. In addition, a performance evaluation in shown on the effectiveness of the SDR approach for space telecommunication.

  18. From WSN towards WoT: Open API Scheme Based on oneM2M Platforms

    Directory of Open Access Journals (Sweden)

    Jaeho Kim

    2016-10-01

    Full Text Available Conventional computing systems have been able to be integrated into daily objects and connected to each other due to advances in computing and network technologies, such as wireless sensor networks (WSNs, forming a global network infrastructure, called the Internet of Things (IoT. To support the interconnection and interoperability between heterogeneous IoT systems, the availability of standardized, open application programming interfaces (APIs is one of the key features of common software platforms for IoT devices, gateways, and servers. In this paper, we present a standardized way of extending previously-existing WSNs towards IoT systems, building the world of the Web of Things (WoT. Based on the oneM2M software platforms developed in the previous project, we introduce a well-designed open API scheme and device-specific thing adaptation software (TAS enabling WSN elements, such as a wireless sensor node, to be accessed in a standardized way on a global scale. Three pilot services are implemented (i.e., a WiFi-enabled smart flowerpot, voice-based control for ZigBee-connected home appliances, and WiFi-connected AR.Drone control to demonstrate the practical usability of the open API scheme and TAS modules. Full details on the method of integrating WSN elements into three example systems are described at the programming code level, which is expected to help future researchers in integrating their WSN systems in IoT platforms, such as oneM2M. We hope that the flexibly-deployable, easily-reusable common open API scheme and TAS-based integration method working with the oneM2M platforms will help the conventional WSNs in diverse industries evolve into the emerging WoT solutions.

  19. From WSN towards WoT: Open API Scheme Based on oneM2M Platforms.

    Science.gov (United States)

    Kim, Jaeho; Choi, Sung-Chan; Ahn, Il-Yeup; Sung, Nak-Myoung; Yun, Jaeseok

    2016-10-06

    Conventional computing systems have been able to be integrated into daily objects and connected to each other due to advances in computing and network technologies, such as wireless sensor networks (WSNs), forming a global network infrastructure, called the Internet of Things (IoT). To support the interconnection and interoperability between heterogeneous IoT systems, the availability of standardized, open application programming interfaces (APIs) is one of the key features of common software platforms for IoT devices, gateways, and servers. In this paper, we present a standardized way of extending previously-existing WSNs towards IoT systems, building the world of the Web of Things (WoT). Based on the oneM2M software platforms developed in the previous project, we introduce a well-designed open API scheme and device-specific thing adaptation software (TAS) enabling WSN elements, such as a wireless sensor node, to be accessed in a standardized way on a global scale. Three pilot services are implemented (i.e., a WiFi-enabled smart flowerpot, voice-based control for ZigBee-connected home appliances, and WiFi-connected AR.Drone control) to demonstrate the practical usability of the open API scheme and TAS modules. Full details on the method of integrating WSN elements into three example systems are described at the programming code level, which is expected to help future researchers in integrating their WSN systems in IoT platforms, such as oneM2M. We hope that the flexibly-deployable, easily-reusable common open API scheme and TAS-based integration method working with the oneM2M platforms will help the conventional WSNs in diverse industries evolve into the emerging WoT solutions.

  20. From WSN towards WoT: Open API Scheme Based on oneM2M Platforms

    Science.gov (United States)

    Kim, Jaeho; Choi, Sung-Chan; Ahn, Il-Yeup; Sung, Nak-Myoung; Yun, Jaeseok

    2016-01-01

    Conventional computing systems have been able to be integrated into daily objects and connected to each other due to advances in computing and network technologies, such as wireless sensor networks (WSNs), forming a global network infrastructure, called the Internet of Things (IoT). To support the interconnection and interoperability between heterogeneous IoT systems, the availability of standardized, open application programming interfaces (APIs) is one of the key features of common software platforms for IoT devices, gateways, and servers. In this paper, we present a standardized way of extending previously-existing WSNs towards IoT systems, building the world of the Web of Things (WoT). Based on the oneM2M software platforms developed in the previous project, we introduce a well-designed open API scheme and device-specific thing adaptation software (TAS) enabling WSN elements, such as a wireless sensor node, to be accessed in a standardized way on a global scale. Three pilot services are implemented (i.e., a WiFi-enabled smart flowerpot, voice-based control for ZigBee-connected home appliances, and WiFi-connected AR.Drone control) to demonstrate the practical usability of the open API scheme and TAS modules. Full details on the method of integrating WSN elements into three example systems are described at the programming code level, which is expected to help future researchers in integrating their WSN systems in IoT platforms, such as oneM2M. We hope that the flexibly-deployable, easily-reusable common open API scheme and TAS-based integration method working with the oneM2M platforms will help the conventional WSNs in diverse industries evolve into the emerging WoT solutions. PMID:27782058

  1. The SEMAINE API: Towards a Standards-Based Framework for Building Emotion-Oriented Systems

    Directory of Open Access Journals (Sweden)

    Marc Schröder

    2010-01-01

    Full Text Available This paper presents the SEMAINE API, an open source framework for building emotion-oriented systems. By encouraging and simplifying the use of standard representation formats, the framework aims to contribute to interoperability and reuse of system components in the research community. By providing a Java and C++ wrapper around a message-oriented middleware, the API makes it easy to integrate components running on different operating systems and written in different programming languages. The SEMAINE system 1.0 is presented as an example of a full-scale system built on top of the SEMAINE API. Three small example systems are described in detail to illustrate how integration between existing and new components is realised with minimal effort.

  2. Building Hypermedia APIs with HTML5 and Node

    CERN Document Server

    Amundsen, Mike

    2011-01-01

    With this concise book, you'll learn the art of building hypermedia APIs that don't simply run on the Web, but that actually exist in the Web. You'll start with the general principles and technologies behind this architectural approach, and then dive hands-on into three fully-functional API examples. Too many APIs rely on concepts rooted in desktop and local area network patterns that don't scale well-costly solutions that are difficult to maintain over time. This book shows system architects and web developers how to design and implement human- and machine-readable web services that remain

  3. Effects of C and Si on strain aging of strain-based API X60 pipeline steels

    Science.gov (United States)

    Sung, Hyo Kyung; Lee, Dong Ho; Lee, Sunghak; Lee, Byeong-Joo; Hong, Seung-Pyo; Kim, Young-Woon; Yoo, Jang Yong; Hwang, Byoungchul; Shin, Sang Yong

    2017-05-01

    Four types of strain-based API X60 pipeline steels were fabricated by varying the C and Si contents, and the effects of C and Si on strain aging were investigated. The 0.05 wt% C steels consisted mainly of polygonal ferrite (PF), whereas the 0.08 wt% C steels consisted of acicular ferrite (AF). The volume fraction of AF increased with increasing C content because C is an austenite stabilizer element. The volume fractions of bainitic ferrite (BF) of the 0.15 wt% Si steels were higher than those of the 0.25 wt% Si steels, whereas the volume fractions of the secondary phases were lower. From the tensile properties before and after the aging process of the strainbased API X60 pipeline steels, the yield strength increased and the uniform and total elongation decreased, which is the strain aging effect. The strain aging effect in the strain-based API X60 pipeline steels was minimized when the volume fraction of AF was increased and secondary phases were distributed uniformly. On the other hand, an excessively high C content formed fine precipitates, and the strain aging effect occurred because of the interactions among dislocations and fine precipitates.

  4. Contracting the Facebook API

    Directory of Open Access Journals (Sweden)

    Ben Rubinger

    2010-09-01

    Full Text Available In recent years, there has been an explosive growth in the popularity of online social networks such as Facebook. In a new twist, third party developers are now able to create their own web applications which plug into Facebook and work with Facebook's "social" data, enabling the entire Facebook user base of more than 400 million active users to use such applications. These client applications can contain subtle errors that can be hard to debug if they misuse the Facebook API. In this paper we present an experience report on applying Microsoft's new code contract system for the .NET framework to the Facebook API.We wrote contracts for several classes in the Facebook API wrapper which allows Microsoft .NET developers to implement Facebook applications. We evaluated the usefulness of these contracts during implementation of a new Facebook application. Our experience indicates that having code contracts provides a better and quicker software development experience.

  5. The Point Lepreau Desktop Simulator

    International Nuclear Information System (INIS)

    MacLean, M.; Hogg, J.; Newman, H.

    1997-01-01

    The Point Lepreau Desktop Simulator runs plant process modeling software on a 266 MHz single CPU DEC Alpha computer. This same Alpha also runs the plant control computer software on an SSCI 125 emulator. An adjacent Pentium PC runs the simulator's Instructor Facility software, and communicates with the Alpha through an Ethernet. The Point Lepreau Desktop simulator is constructed to be as similar as possible to the Point Lepreau full scope training simulator. This minimizes total maintenance costs and enhances the benefits of the desktop simulator. Both simulators have the same modeling running on a single CPU in the same schedule of calculations. Both simulators have the same Instructor Facility capable of developing and executing the same lesson plans, doing the same monitoring and control of simulations, inserting all the same malfunctions, performing all the same overrides, capable of making and restoring all the same storepoints. Both simulators run the same plant control computer software - the same assembly language control programs as the power plant uses for reactor control, heat transport control, annunciation, etc. This is a higher degree of similarity between a desktop simulator and a full scope training simulator than previously reported for a computer controlled nuclear plant. The large quantity of control room hardware missing from the desktop simulator is replaced by software. The Instructor Facility panel override software of the training simulator provides the means by which devices (switches, controllers, windows, etc.) on the control room panels can be controlled and monitored in the desktop simulator. The CRT of the Alpha provides a mouse operated DCC keyboard mimic for controlling the plant control computer emulation. Two emulated RAMTEK display channels appear as windows for monitoring anything of interest on plant DCC displays, including one channel for annunciation. (author)

  6. Pathway projector: web-based zoomable pathway browser using KEGG atlas and Google Maps API.

    Science.gov (United States)

    Kono, Nobuaki; Arakawa, Kazuharu; Ogawa, Ryu; Kido, Nobuhiro; Oshita, Kazuki; Ikegami, Keita; Tamaki, Satoshi; Tomita, Masaru

    2009-11-11

    Biochemical pathways provide an essential context for understanding comprehensive experimental data and the systematic workings of a cell. Therefore, the availability of online pathway browsers will facilitate post-genomic research, just as genome browsers have contributed to genomics. Many pathway maps have been provided online as part of public pathway databases. Most of these maps, however, function as the gateway interface to a specific database, and the comprehensiveness of their represented entities, data mapping capabilities, and user interfaces are not always sufficient for generic usage. We have identified five central requirements for a pathway browser: (1) availability of large integrated maps showing genes, enzymes, and metabolites; (2) comprehensive search features and data access; (3) data mapping for transcriptomic, proteomic, and metabolomic experiments, as well as the ability to edit and annotate pathway maps; (4) easy exchange of pathway data; and (5) intuitive user experience without the requirement for installation and regular maintenance. According to these requirements, we have evaluated existing pathway databases and tools and implemented a web-based pathway browser named Pathway Projector as a solution. Pathway Projector provides integrated pathway maps that are based upon the KEGG Atlas, with the addition of nodes for genes and enzymes, and is implemented as a scalable, zoomable map utilizing the Google Maps API. Users can search pathway-related data using keywords, molecular weights, nucleotide sequences, and amino acid sequences, or as possible routes between compounds. In addition, experimental data from transcriptomic, proteomic, and metabolomic analyses can be readily mapped. Pathway Projector is freely available for academic users at (http://www.g-language.org/PathwayProjector/).

  7. Enersave API: Android-based power-saving framework for mobile devices

    Directory of Open Access Journals (Sweden)

    A.M. Muharum

    2017-06-01

    Full Text Available Power consumption is a major factor to be taken into consideration when using mobile devices in the IoT field. Good Power management requires proper understanding of the way in which it is being consumed by the end-devices. This paper is a continuation of the work in Ref. [1] and proposes an energy saving API for the Android Operating System in order to help developers turn their applications into energy-aware ones. The main features heavily used for building smart applications, greatly impact battery life of Android devices and which have been taken into consideration are: Screen brightness, Colour scheme, CPU frequency, 2G/3G network, Maps, Low power localisation, Bluetooth and Wi-Fi. The assessment of the power-saving API has been performed on real Android devices and also compared to the most powerful power-saving applications – DU Battery Saver and Battery Saver 2016 – currently available on the Android market. Comparisons demonstrate that the Enersave API has a significant impact on power saving when incorporated in android applications. While DU Battery Saver and Battery Saver 2016 help saving 22.2% and 40.5% of the battery power respectively, the incorporation of the Enersave API in android applications can help save 84.6% of battery power.

  8. The IRMIS object model and services API

    International Nuclear Information System (INIS)

    Saunders, C.; Dohan, D.A.; Arnold, N.D.

    2005-01-01

    The relational model developed for the Integrated Relational Model of Installed Systems (IRMIS) toolkit has been successfully used to capture the Advanced Photon Source (APS) control system software (EPICS process variables and their definitions). The relational tables are populated by a crawler script that parses each Input/Output Controller (IOC) start-up file when an IOC reboot is detected. User interaction is provided by a Java Swing application that acts as a desktop for viewing the process variable information. Mapping between the display objects and the relational tables was carried out with the Hibernate Object Relational Modeling (ORM) framework. Work is well underway at the APS to extend the relational modeling to include control system hardware. For this work, due in part to the complex user interaction required, the primary application development environment has shifted from the relational database view to the object oriented (Java) perspective. With this approach, the business logic is executed in Java rather than in SQL stored procedures. This paper describes the object model used to represent control system software, hardware, and interconnects in IRMIS. We also describe the services API used to encapsulate the required behaviors for creating and maintaining the complex data. In addition to the core schema and object model, many important concepts in IRMIS are captured by the services API. IRMIS is an ambitious collaborative effort for defining and developing a relational database and associated applications to comprehensively document the large and complex EPICS-based control systems of today's accelerators. The documentation effort includes process variables, control system hardware, and interconnections. The approach could also be used to document all components of the accelerator, including mechanical, vacuum, power supplies, etc. One key aspect of IRMIS is that it is a documentation framework, not a design and development tool. We do not

  9. Web-Based Interrogation of Large-Scale Geophysical Data Sets and Clustering Analysis of Many Earthquake Events From Desktop and Handheld Computers

    Science.gov (United States)

    Garbow, Z. A.; Erlebacher, G.; Yuen, D. A.; Sevre, E. O.; Nagle, A. R.; Kaneko, J. Y.

    2002-12-01

    The size of datasets in the geosciences is growing at a tremendous pace due to inexpensive memory, increasingly large storage space, fast processors and constantly improving data-collection instruments. However, the available bandwidth increases at a much slower rate and consequently cannot keep up with the size of the datasets themselves. Coupled with our need to explore the large datasets in a simplified point of view, the current approach of transferring full datasets from one machine to another in order to analyze it is fast becoming impractical and obsolete. We have previously developed a web-based interactive data interrogation system that allows users to remotely analyze geophysical data over the Internet using a client-server paradigm (Garbow et al., Electronic Geosciences, Vol. 6, 2001). To further our idea of interactive data extraction we have used this interrogative system to explore both high-resolution mantle convection data and earthquake clusters involving up to tens of thousands of earthquakes. In addition, we have ported this system to work from handheld devices via wireless connections. Our system uses a combination of Java, Python, and C for running remotely from a desktop computer, laptop, or even a handheld device, while incorporating the power and memory capacity of a large workstation server. Because of the limitations of the current generation of handheld devices in terms of processing power, screen size, memory and storage, they have not yet become practical vehicles for useful scientific work. Our aim is to successfully overcome the limitations of handheld devices to allow them in the near future to be used as portable scientific research laboratories, particularly with the new, more powerful processors (e.g. Transmeta Crusoe) just over the horizon.

  10. When the Internet Knocks, Unlock the Desktop.

    Science.gov (United States)

    Nyerges, Mike

    1999-01-01

    Describes one public school library's struggles and solutions to problems associated with managing its new Windows desktop. To implement goals for organizing the desktop, the library selected the FoolProof desktop security system, utilized networks administration to enforce the school's Acceptable Use Policy, and used Windows 95 System Policies.…

  11. Drug Interaction API

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Interaction API is a web service for accessing drug-drug interactions. No license is needed to use the Interaction API. Currently, the API uses DrugBank for its...

  12. Honey bee (Apis mellifera) nurses do not consume pollens based on their nutritional quality

    OpenAIRE

    Corby-Harris, Vanessa; Snyder, Lucy; Meador, Charlotte; Ayotte, Trace

    2018-01-01

    Honey bee workers (Apis mellifera) consume a variety of pollens to meet the majority of their requirements for protein and lipids. Recent work indicates that honey bees prefer diets that reflect the proper ratio of nutrients necessary for optimal survival and homeostasis. This idea relies on the precept that honey bees evaluate the nutritional composition of the foods provided to them. While this has been shown in bumble bees, the data for honey bees are mixed. Further, there is controversy a...

  13. Corrosion resistance of ERW (Electric Resistance Welded) seam welds as compared to metal base in API 5L steel pipes

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez Velasquez, Jorge L.; Godinez Salcedo, Jesus G.; Lopez Fajardo, Pedro [Instituto Politecnico Nacional (IPN), Mexico D.F. (Mexico). Escuela Superior de Ingenieria Quimica e Industrias Extractivas (ESIQIE). Dept. de Ingenieria Metalurgica

    2009-07-01

    The corrosion resistance of ERW seam welds and the base metal in API 5L X70 steel pipes was evaluated by Tafel tests. The procedure was according to ASTM G3 standard. The study was completed with metallographic and chemical characterization of the tested zones, that is, the welded zone and the base metal away of the weld. All tests were made on the internal surface of the pipe in order to assess the internal corrosion of an in-service pipeline made of the API 5L X70 steel. The test solution was acid brine prepared according to NACE Publications 1D182 and 1D196. The results showed that the ERW seam weld corrodes as much as three times faster than the base material. This behavior is attributed to a more heterogeneous microstructure with higher internal energy in the ERW seam weld zone, as compared to the base metal, which is basically a ferrite pearlite microstructure in a normalized condition. This result also indicates that pipeline segments made of ERW steel pipe where the seam weld is located near or at the bottom of the pipe are prone to a highly localized attack that may form channels of metal loss if there is water accumulation at the bottom of the pipeline. (author)

  14. Scaling Critical Zone analysis tasks from desktop to the cloud utilizing contemporary distributed computing and data management approaches: A case study for project based learning of Cyberinfrastructure concepts

    Science.gov (United States)

    Swetnam, T. L.; Pelletier, J. D.; Merchant, N.; Callahan, N.; Lyons, E.

    2015-12-01

    Earth science is making rapid advances through effective utilization of large-scale data repositories such as aerial LiDAR and access to NSF-funded cyberinfrastructures (e.g. the OpenTopography.org data portal, iPlant Collaborative, and XSEDE). Scaling analysis tasks that are traditionally developed using desktops, laptops or computing clusters to effectively leverage national and regional scale cyberinfrastructure pose unique challenges and barriers to adoption. To address some of these challenges in Fall 2014 an 'Applied Cyberinfrastructure Concepts' a project-based learning course (ISTA 420/520) at the University of Arizona focused on developing scalable models of 'Effective Energy and Mass Transfer' (EEMT, MJ m-2 yr-1) for use by the NSF Critical Zone Observatories (CZO) project. EEMT is a quantitative measure of the flux of available energy to the critical zone, and its computation involves inputs that have broad applicability (e.g. solar insolation). The course comprised of 25 students with varying level of computational skills and with no prior domain background in the geosciences, collaborated with domain experts to develop the scalable workflow. The original workflow relying on open-source QGIS platform on a laptop was scaled to effectively utilize cloud environments (Openstack), UA Campus HPC systems, iRODS, and other XSEDE and OSG resources. The project utilizes public data, e.g. DEMs produced by OpenTopography.org and climate data from Daymet, which are processed using GDAL, GRASS and SAGA and the Makeflow and Work-queue task management software packages. Students were placed into collaborative groups to develop the separate aspects of the project. They were allowed to change teams, alter workflows, and design and develop novel code. The students were able to identify all necessary dependencies, recompile source onto the target execution platforms, and demonstrate a functional workflow, which was further improved upon by one of the group leaders over

  15. Study of an API migration for two XML APIs

    NARCIS (Netherlands)

    T.T. Bartholomei; K. Czarnecki; R. Lämmel (Ralf); T. van der Storm (Tijs); M.G.J. van den Brand (Mark); D. Gasevic; J. Gray

    2010-01-01

    htmlabstractAPI migration refers to adapting an application such that its dependence on a given API (the source API) is eliminated in favor of depending on an alternative API (the target API) with the source and target APIs serving the same domain. One may attempt to automate API migration by code

  16. Desktop Computing - Distributed Cognition in a Tax Office

    Directory of Open Access Journals (Sweden)

    Martin Nielsen

    2004-05-01

    Full Text Available Based on a detailed study of the use of representations in a tax assessment process, this paper presents an analysis of the use of the physical desktop and of paper documents, files and electronic information. This analysis challenges the ways in which the computer desktop is designed and used normally, and we present a number of challenges to user interface design. Taking these seriously, means to revisit several taken-for-granted elements of the current WIMP regime: the randomly overlapping windows on a non-structured background; the lack of traces of time and past location; and the individualised and non-activity-oriented set-up of the desktop.

  17. Digital video for the desktop

    CERN Document Server

    Pender, Ken

    1999-01-01

    Practical introduction to creating and editing high quality video on the desktop. Using examples from a variety of video applications, benefit from a professional's experience, step-by-step, through a series of workshops demonstrating a wide variety of techniques. These include producing short films, multimedia and internet presentations, animated graphics and special effects.The opportunities for the independent videomaker have never been greater - make sure you bring your understanding fully up to date with this invaluable guide.No prior knowledge of the technology is assumed, with explanati

  18. PyGOLD: a python based API for docking based virtual screening workflow generation.

    Science.gov (United States)

    Patel, Hitesh; Brinkjost, Tobias; Koch, Oliver

    2017-08-15

    Molecular docking is one of the successful approaches in structure based discovery and development of bioactive molecules in chemical biology and medicinal chemistry. Due to the huge amount of computational time that is still required, docking is often the last step in a virtual screening approach. Such screenings are set as workflows spanned over many steps, each aiming at different filtering task. These workflows can be automatized in large parts using python based toolkits except for docking using the docking software GOLD. However, within an automated virtual screening workflow it is not feasible to use the GUI in between every step to change the GOLD configuration file. Thus, a python module called PyGOLD was developed, to parse, edit and write the GOLD configuration file and to automate docking based virtual screening workflows. The latest version of PyGOLD, its documentation and example scripts are available at: http://www.ccb.tu-dortmund.de/koch or http://www.agkoch.de. PyGOLD is implemented in Python and can be imported as a standard python module without any further dependencies. oliver.koch@agkoch.de, oliver.koch@tu-dortmund.de. Supplementary data are available at Bioinformatics online. © The Author (2017). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  19. Design of All Digital Flight Program Training Desktop Application System

    Directory of Open Access Journals (Sweden)

    Li Yu

    2017-01-01

    Full Text Available All digital flight program training desktop application system operating conditions are simple. Can make the aircraft aircrew learning theory and operation training closely. Improve the training efficiency and effectiveness. This paper studies the application field and design requirements of flight program training system. Based on the WINDOWS operating system desktop application, the design idea and system architecture of the all digital flight program training system are put forward. Flight characteristics, key airborne systems and aircraft cockpit are simulated. Finally, By comparing flight training simulator and the specific script program training system, The characteristics and advantages of the training system are analyzed in this paper.

  20. An Exercise in Desktop Publishing: Using the "Newsroom."

    Science.gov (United States)

    Kiteka, Sebastian F.

    This guide provides a description and step-by-step instructions for the use of "Newsroom," a desktop-publishing program for the Apple II series of microcomputers produced by Springboard Software Inc. Based on the 1984 version of the program, this two-hour exercise focuses on the design and production of a newsletter with text and…

  1. Comparing Web Applications with Desktop Applications: An Empirical Study

    DEFF Research Database (Denmark)

    Pop, Paul

    2002-01-01

    of developing and using such applications. In this paper we present a comparison of web and desktop applications from the usability point of view. The comparison is based on an empirical study that investigates the performance of a group of users on two calendaring applications: Yahoo!Calendar and Microsoft...

  2. Healthcare Finder API

    Data.gov (United States)

    U.S. Department of Health & Human Services — All of the data used on the Finder.HealthCare.gov web application is available through this API. There are multiple collections of data available through the API. 1....

  3. Instant Citrix XenDesktop 5 starter

    CERN Document Server

    Magdy, Mahmoud

    2013-01-01

    Get to grips with a new technology, understand what it is and what it can do for you, and then get to work with the most important features and tasks. This easy-to-follow, hands-on guide shows you how to implement desktop virtualization with real life cases and step-by-step instructions. It is a tutorial with step-by-step instructions and adequate screenshots for the installation and administration of Citrix XenDesktop.If you are new to XenDesktop or are looking to build your skills in desktop virtualization, this is your step-by-step guide to learning Citrix XenDesktop. For those architects a

  4. Desktop supercomputer: what can it do?

    Science.gov (United States)

    Bogdanov, A.; Degtyarev, A.; Korkhov, V.

    2017-12-01

    The paper addresses the issues of solving complex problems that require using supercomputers or multiprocessor clusters available for most researchers nowadays. Efficient distribution of high performance computing resources according to actual application needs has been a major research topic since high-performance computing (HPC) technologies became widely introduced. At the same time, comfortable and transparent access to these resources was a key user requirement. In this paper we discuss approaches to build a virtual private supercomputer available at user's desktop: a virtual computing environment tailored specifically for a target user with a particular target application. We describe and evaluate possibilities to create the virtual supercomputer based on light-weight virtualization technologies, and analyze the efficiency of our approach compared to traditional methods of HPC resource management.

  5. Perancangan Sistem Otomatis Update Pada Aplikasi Desktop Abios

    Directory of Open Access Journals (Sweden)

    Karto Iskandar

    2010-12-01

    Full Text Available Unlike web applications easier to update the latest version, desktop applications more difficult and must involve the user in doing so. It is caused by a desktop application is an application that is installed in the computer user. The purpose of this research is to design an automatic system updates on a desktop application, an example case: Application Binus International Operational Support (ABIOS. This research used literature study and system design. In desktop applications, often there is update the latest applications that are not known to the user who sometimes fatal and disrupt business operations. Generally, developer will inform the changes version to user that they can update the application. In an update of applications, should be done by the system automatically, not manually by users. Once in a while, the user background is not from computer base. After doing the research, it can be concluded that the system automatically updates the application has benefits to users in obtaining information regarding the latest version, and can assist in automatically update the latest application is based on computerization. For further development of this system is expected to operate on multi platforms and or mobile applications. 

  6. GREEN SUPERCOMPUTING IN A DESKTOP BOX

    Energy Technology Data Exchange (ETDEWEB)

    HSU, CHUNG-HSING [Los Alamos National Laboratory; FENG, WU-CHUN [NON LANL; CHING, AVERY [NON LANL

    2007-01-17

    The computer workstation, introduced by Sun Microsystems in 1982, was the tool of choice for scientists and engineers as an interactive computing environment for the development of scientific codes. However, by the mid-1990s, the performance of workstations began to lag behind high-end commodity PCs. This, coupled with the disappearance of BSD-based operating systems in workstations and the emergence of Linux as an open-source operating system for PCs, arguably led to the demise of the workstation as we knew it. Around the same time, computational scientists started to leverage PCs running Linux to create a commodity-based (Beowulf) cluster that provided dedicated computer cycles, i.e., supercomputing for the rest of us, as a cost-effective alternative to large supercomputers, i.e., supercomputing for the few. However, as the cluster movement has matured, with respect to cluster hardware and open-source software, these clusters have become much more like their large-scale supercomputing brethren - a shared (and power-hungry) datacenter resource that must reside in a machine-cooled room in order to operate properly. Consequently, the above observations, when coupled with the ever-increasing performance gap between the PC and cluster supercomputer, provide the motivation for a 'green' desktop supercomputer - a turnkey solution that provides an interactive and parallel computing environment with the approximate form factor of a Sun SPARCstation 1 'pizza box' workstation. In this paper, they present the hardware and software architecture of such a solution as well as its prowess as a developmental platform for parallel codes. In short, imagine a 12-node personal desktop supercomputer that achieves 14 Gflops on Linpack but sips only 185 watts of power at load, resulting in a performance-power ratio that is over 300% better than their reference SMP platform.

  7. Honey bee (Apis mellifera) nurses do not consume pollens based on their nutritional quality

    Science.gov (United States)

    Snyder, Lucy; Meador, Charlotte; Ayotte, Trace

    2018-01-01

    Honey bee workers (Apis mellifera) consume a variety of pollens to meet the majority of their requirements for protein and lipids. Recent work indicates that honey bees prefer diets that reflect the proper ratio of nutrients necessary for optimal survival and homeostasis. This idea relies on the precept that honey bees evaluate the nutritional composition of the foods provided to them. While this has been shown in bumble bees, the data for honey bees are mixed. Further, there is controversy as to whether foragers can evaluate the nutritional value of pollens, especially if they do not consume it. Here, we focused on nurse workers, who eat most of the pollen coming into the hive. We tested the hypothesis that nurses prefer diets with higher nutritional value. We first determined the nutritional profile, number of plant taxa (richness), and degree of hypopharyngeal gland (HG) growth conferred by three honey bee collected pollens. We then presented nurses with these same three pollens in paired choice assays and measured consumption. To further test whether nutrition influenced preference, we also presented bees with natural pollens supplemented with protein or lipids and liquid diets with protein and lipid ratios equal to the natural pollens. Different pollens conferred different degrees of HG growth, but despite these differences, nurse bees did not always prefer the most nutritious pollens. Adding protein and/or lipids to less desirable pollens minimally increased pollen attractiveness, and nurses did not exhibit a strong preference for any of the three liquid diets. We conclude that different pollens provide different nutritional benefits, but that nurses either cannot or do not assess pollen nutritional value. This implies that the nurses may not be able to communicate information about pollen quality to the foragers, who regulate the pollens coming into the hive. PMID:29324841

  8. Honey bee (Apis mellifera nurses do not consume pollens based on their nutritional quality.

    Directory of Open Access Journals (Sweden)

    Vanessa Corby-Harris

    Full Text Available Honey bee workers (Apis mellifera consume a variety of pollens to meet the majority of their requirements for protein and lipids. Recent work indicates that honey bees prefer diets that reflect the proper ratio of nutrients necessary for optimal survival and homeostasis. This idea relies on the precept that honey bees evaluate the nutritional composition of the foods provided to them. While this has been shown in bumble bees, the data for honey bees are mixed. Further, there is controversy as to whether foragers can evaluate the nutritional value of pollens, especially if they do not consume it. Here, we focused on nurse workers, who eat most of the pollen coming into the hive. We tested the hypothesis that nurses prefer diets with higher nutritional value. We first determined the nutritional profile, number of plant taxa (richness, and degree of hypopharyngeal gland (HG growth conferred by three honey bee collected pollens. We then presented nurses with these same three pollens in paired choice assays and measured consumption. To further test whether nutrition influenced preference, we also presented bees with natural pollens supplemented with protein or lipids and liquid diets with protein and lipid ratios equal to the natural pollens. Different pollens conferred different degrees of HG growth, but despite these differences, nurse bees did not always prefer the most nutritious pollens. Adding protein and/or lipids to less desirable pollens minimally increased pollen attractiveness, and nurses did not exhibit a strong preference for any of the three liquid diets. We conclude that different pollens provide different nutritional benefits, but that nurses either cannot or do not assess pollen nutritional value. This implies that the nurses may not be able to communicate information about pollen quality to the foragers, who regulate the pollens coming into the hive.

  9. Honey bee (Apis mellifera) nurses do not consume pollens based on their nutritional quality.

    Science.gov (United States)

    Corby-Harris, Vanessa; Snyder, Lucy; Meador, Charlotte; Ayotte, Trace

    2018-01-01

    Honey bee workers (Apis mellifera) consume a variety of pollens to meet the majority of their requirements for protein and lipids. Recent work indicates that honey bees prefer diets that reflect the proper ratio of nutrients necessary for optimal survival and homeostasis. This idea relies on the precept that honey bees evaluate the nutritional composition of the foods provided to them. While this has been shown in bumble bees, the data for honey bees are mixed. Further, there is controversy as to whether foragers can evaluate the nutritional value of pollens, especially if they do not consume it. Here, we focused on nurse workers, who eat most of the pollen coming into the hive. We tested the hypothesis that nurses prefer diets with higher nutritional value. We first determined the nutritional profile, number of plant taxa (richness), and degree of hypopharyngeal gland (HG) growth conferred by three honey bee collected pollens. We then presented nurses with these same three pollens in paired choice assays and measured consumption. To further test whether nutrition influenced preference, we also presented bees with natural pollens supplemented with protein or lipids and liquid diets with protein and lipid ratios equal to the natural pollens. Different pollens conferred different degrees of HG growth, but despite these differences, nurse bees did not always prefer the most nutritious pollens. Adding protein and/or lipids to less desirable pollens minimally increased pollen attractiveness, and nurses did not exhibit a strong preference for any of the three liquid diets. We conclude that different pollens provide different nutritional benefits, but that nurses either cannot or do not assess pollen nutritional value. This implies that the nurses may not be able to communicate information about pollen quality to the foragers, who regulate the pollens coming into the hive.

  10. Android quick APIs reference

    CERN Document Server

    Cinar, Onur

    2015-01-01

    The Android Quick APIs Reference is a condensed code and APIs reference for the new Google Android 5.0 SDK. It presents the essential Android APIs in a well-organized format that can be used as a handy reference. You won't find any technical jargon, bloated samples, drawn out history lessons, or witty stories in this book. What you will find is a software development kit and APIs reference that is concise, to the point and highly accessible. The book is packed with useful information and is a must-have for any mobile or Android app developer or programmer. In the Android Quick APIs Refe

  11. Population resizing on fitness improvement genetic algorithm to optimize promotion visit route based on android and google maps API

    Science.gov (United States)

    Listyorini, Tri; Muzid, Syafiul

    2017-06-01

    The promotion team of Muria Kudus University (UMK) has done annual promotion visit to several senior high schools in Indonesia. The visits were done to numbers of schools in Kudus, Jepara, Demak, Rembang and Purwodadi. To simplify the visit, each visit round is limited to 15 (fifteen) schools. However, the team frequently faces some obstacles during the visit, particularly in determining the route that they should take toward the targeted school. It is due to the long distance or the difficult route to reach the targeted school that leads to elongated travel duration and inefficient fuel cost. To solve these problems, the development of a certain application using heuristic genetic algorithm method based on the dynamic of population size or Population Resizing on Fitness lmprovement Genetic Algorithm (PRoFIGA), was done. This android-based application was developed to make the visit easier and to determine a shorter route for the team, hence, the visiting period will be effective and efficient. The result of this research was an android-based application to determine the shortest route by combining heuristic method and Google Maps Application Programming lnterface (API) that display the route options for the team.

  12. Systems Engineering Model and Training Application for Desktop Environment

    Science.gov (United States)

    May, Jeffrey T.

    2010-01-01

    Provide a graphical user interface based simulator for desktop training, operations and procedure development and system reference. This simulator allows for engineers to train and further understand the dynamics of their system from their local desktops. It allows the users to train and evaluate their system at a pace and skill level based on the user's competency and from a perspective based on the user's need. The simulator will not require any special resources to execute and should generally be available for use. The interface is based on a concept of presenting the model of the system in ways that best suits the user's application or training needs. The three levels of views are Component View, the System View (overall system), and the Console View (monitor). These views are portals into a single model, so changing the model from one view or from a model manager Graphical User Interface will be reflected on all other views.

  13. Enterprise Collaboration Framework for Managing, Advancing and Unifying the Functionality of Multiple Cloud-Based Services with the Help of a Graph API

    OpenAIRE

    Petychakis, Michael; Alvertis, Iosif; Biliri, Evmorfia; Tsouroplis, Romanos; Lampathaki, Fenareti; Askounis, Dimitris

    2014-01-01

    Part 5: Service Orientation in Collaborative Networks; International audience; Nowadays, the proliferation of cloud-based services (CBS) has revolutionized the way people communicate, connect, share and eventually conduct business. Large and small and medium enterprises often adapt to this era by providing their core competence through an API. The present paper aims at describing a solution that manages, advances and unifies the functionality of the various CBS under a common framework that i...

  14. Mars Propellant Liquefaction Modeling in Thermal Desktop

    Science.gov (United States)

    Desai, Pooja; Hauser, Dan; Sutherlin, Steven

    2017-01-01

    NASAs current Mars architectures are assuming the production and storage of 23 tons of liquid oxygen on the surface of Mars over a duration of 500+ days. In order to do this in a mass efficient manner, an energy efficient refrigeration system will be required. Based on previous analysis NASA has decided to do all liquefaction in the propulsion vehicle storage tanks. In order to allow for transient Martian environmental effects, a propellant liquefaction and storage system for a Mars Ascent Vehicle (MAV) was modeled using Thermal Desktop. The model consisted of a propellant tank containing a broad area cooling loop heat exchanger integrated with a reverse turbo Brayton cryocooler. Cryocooler sizing and performance modeling was conducted using MAV diurnal heat loads and radiator rejection temperatures predicted from a previous thermal model of the MAV. A system was also sized and modeled using an alternative heat rejection system that relies on a forced convection heat exchanger. Cryocooler mass, input power, and heat rejection for both systems were estimated and compared against sizing based on non-transient sizing estimates.

  15. Application of desktop computers in nuclear engineering education

    International Nuclear Information System (INIS)

    Graves, H.W. Jr.

    1990-01-01

    Utilization of desktop computers in the academic environment is based on the same objectives as in the industrial environment - increased quality and efficiency. Desktop computers can be extremely useful teaching tools in two general areas: classroom demonstrations and homework assignments. Although differences in emphasis exist, tutorial programs share many characteristics with interactive software developed for the industrial environment. In the Reactor Design and Fuel Management course at the University of Maryland, several interactive tutorial programs provided by Energy analysis Software Service have been utilized. These programs have been designed to be sufficiently structured to permit an orderly, disciplined solution to the problem being solved, and yet be flexible enough to accommodate most problem solution options

  16. An API-based search system for one click access to information

    NARCIS (Netherlands)

    Ionita, Dan; Tax, Niek; Hiemstra, Djoerd

    This paper proposes a prototype One Click access system, based on previous work in the field and the related 1CLICK-2@NTCIR10 task. The proposed solution integrates methods from into a three tier algorithm: query categorization, information extraction and output generation and offers suggestions on

  17. The Dutch xAPI Experience: xAPI Recipes

    OpenAIRE

    Berg, Alan; Scheffel, Maren; Drachsler, Hendrik; Ternier, Stefaan; Specht, Marcus

    2017-01-01

    We present the collected experiences since 2012 of the Dutch Special Interest Group (SIG) for Learning Analytics in the application of the xAPI standard and best practices around the application of xAPI in various contexts. We present three projects that apply xAPI in very different ways and publish a consistent set of xAPI recipes.

  18. DIRAC RESTful API

    International Nuclear Information System (INIS)

    Casajus Ramo, A; Graciani Diaz, R; Tsaregorodtsev, A

    2012-01-01

    The DIRAC framework for distributed computing has been designed as a flexible and modular solution that can be adapted to the requirements of any community. Users interact with DIRAC via command line, using the web portal or accessing resources via the DIRAC python API. The current DIRAC API requires users to use a python version valid for DIRAC. Some communities have developed their own software solutions for handling their specific workload, and would like to use DIRAC as their back-end to access distributed computing resources easily. Many of these solutions are not coded in python or depend on a specific python version. To solve this gap DIRAC provides a new language agnostic API that any software solution can use. This new API has been designed following the RESTful principles. Any language with libraries to issue standard HTTP queries may use it. GSI proxies can still be used to authenticate against the API services. However GSI proxies are not a widely adopted standard. The new DIRAC API also allows clients to use OAuth for delegating the user credentials to a third party solution. These delegated credentials allow the third party software to query to DIRAC on behalf of the users. This new API will further expand the possibilities communities have to integrate DIRAC into their distributed computing models.

  19. Thomas Jefferson, Page Design, and Desktop Publishing.

    Science.gov (United States)

    Hartley, James

    1991-01-01

    Discussion of page design for desktop publishing focuses on the importance of functional issues as opposed to aesthetic issues, and criticizes a previous article that stressed aesthetic issues. Topics discussed include balance, consistency in text structure, and how differences in layout affect the clarity of "The Declaration of…

  20. Desktop Virtualization in Action: Simplicity Is Power

    Science.gov (United States)

    Fennell, Dustin

    2010-01-01

    Discover how your institution can better manage and increase access to instructional applications and desktops while providing a blended learning environment. Receive practical insight into how academic computing virtualization can be leveraged to enhance education at your institution while lowering Total Cost of Ownership (TCO) and reducing the…

  1. Aquatic Habitats: Exploring Desktop Ponds. Teacher's Guide.

    Science.gov (United States)

    Barrett, Katharine; Willard, Carolyn

    This book, for grades 2-6, is designed to provide students with a highly motivating and unique opportunity to investigate an aquatic habitat. Students set up, observe, study, and reflect upon their own "desktop ponds." Accessible plants and small animals used in these activities include Elodea, Tubifex worms, snails, mosquito larvae, and fish.…

  2. Architectural Desktop : release 3.3

    DEFF Research Database (Denmark)

    Skauge, Jørn

    2002-01-01

    Øvelser i ADT's mest grundlæggende dele på basis af modellering af et lille og simpelt hus. Der arbejdes primært med værktøjerne i designdelens menu. 1. udgave med titel: Architectural Desktop (Fiskers hus). 2002. 60 sider....

  3. Robust formulation for the design of tissue engineering scaffolds: A comprehensive study on structural anisotropy, viscoelasticity and degradation of 3D scaffolds fabricated with customized desktop robot based rapid prototyping (DRBRP) system.

    Science.gov (United States)

    Hoque, M Enamul

    2017-03-01

    This study investigates the scaffolds' structural anisotropy (i.e. the effect of loading direction), viscoelasticity (i.e. the effect of cross head speed or strain rate), and the influence of simulated physiological environment (PBS solution at 37°C) on the mechanical properties. Besides, the in vitro degradation study has also been performed that evaluates the effect of variation in material and lay-down pattern on the scaffolds' degradation kinetics in terms of mass loss, and change in morphological and mechanical properties. Porous three dimensional (3D) scaffolds of polycarprolactone (PCL) and polycarprolactone-polyethylene glycol (PCL-PEG) were developed by laying down the microfilaments directionally layer-by-layer using an in-house built computer-controlled extrusion and deposition process, called desktop robot based rapid prototyping (DRBRP) system. The loading direction, strain rate and physiological environment directly influenced the mechanical properties of the scaffolds. In vitro degradation study demonstrated that both PCL and PCL-PEG scaffolds realized homogeneous hydrolytic degradation via surface erosion resulting in a consistent and predictable mass loss. The linear mass loss caused uniform and linear increase in porosity that accordingly led to the decrease in mechanical properties. The synthetic polymer had the potential to modulate hydrophilicity and/or degradability and consequently, the biomechanical properties of the scaffolds by varying the polymer constituents. Copyright © 2016 Elsevier B.V. All rights reserved.

  4. GIBS API for Developers

    Data.gov (United States)

    National Aeronautics and Space Administration — API using Global Imagery Browse Services (GIBS) designed to deliver global, full-resolution satellite imagery to users in a highly responsive manner, enabling...

  5. Mars Rover Photos API

    Data.gov (United States)

    National Aeronautics and Space Administration — This API is designed to collect image data gathered by NASA's Curiosity, Opportunity, and Spirit rovers on Mars and make it more easily available to other...

  6. Mashupy a kultura API

    OpenAIRE

    Hutníková, Eliška

    2010-01-01

    Thesis examines the current state of development and possible directions for further growth in the creation and use of mashups and hybrid application software that works with the application programming interface (API). At the beginning, the work examines the development of technologies that have enabled the creation of mashups and hybrid applications. The thesis also examines the economic aspects and sets the trend of using the API within the context of reasoning on Web 2.0. Another part dea...

  7. IBM System i APIs at Work

    CERN Document Server

    Vining, Bruce; Hawkins, Ron

    2007-01-01

    This new edition of the bestselling i5 application programming interface (API) book includes powerful new APIs and updated code to give programmers a working knowledge of the APIs available under i5/OS. Using real business-world examples, this book explains APIs that serve webpages, list APIs, APIs that work with user spaces, dynamic index APIs, APIs that retrieve system values, job information and job queue information APIs, APIs that work with data queues, APIs for error handling and message handling, and spool file APIs, among many others. Completely revised and including eight new chapters

  8. Identification of Yersinia enterocolitica in minced meat: a comparative analysis of API 20E, Yersinia identification kit and a 16S rRNA-based PCR method.

    Science.gov (United States)

    Arnold, T; Neubauer, H; Nikolaou, K; Roesler, U; Hensel, A

    2004-02-01

    The isolation and identification of Yersinia enterocolitica from minced meat on CIN agar medium is still one of the major problems in food microbiology because of the low selectivity of cefsulodin-irgasan-novobiocin (CIN) agar. A total of 198 minced meat samples were collected from commercial establishments (butcher shops and supermarkets) in seven German cities in order to investigate the sensitivity and specificity of three identification techniques suitable for the differentiation of Y. enterocolitica within the rich background flora on CIN agar plates. As expected isolation of Y. enterocolitica from minced meat on CIN agar medium after 72 h enrichment in peptone, sorbitol and bile salts (PSB) broth was difficult because all plates were abundantly covered with numerous 'typical'Yersinia-like colonies of bull's eye appearance as well as with atypical colonies. Based on the phenotype of the colonies it was possible to detect colonies showing Yersinia-like growth on CIN agar in 52 samples (26%). For identification of Y. enterocolitica the API 20E system (bioMerieux, Nürtingen, Germany), the Yersinia identification kit (Merlin, Bornheim-Hersel, Germany) and a 16S rRNA based PCR assay were compared. Only in one sample (0.5%) a Y. enterocolitica strain was detected by all methods. Of the three identification systems tested for routine laboratory diagnostics the API 20E system was found to be the most suitable tool to identify Y. enterocolitica colonies within the rich background flora from minced meat samples on CIN agar plates.

  9. Remote desktop with HTML5 technology

    OpenAIRE

    Banič, Žiga

    2013-01-01

    In our thesis we implemented a remote desktop with the newest technology HTML5. The main reason we choose this technology is to access the system through many different computing platforms. Present web browsers take care for the right support of using before mentioned technology. With the new element canvas we can manipulate and display the remote computer. To manipulate the system we just add event listeners for mouse, keyboard and touch events on the element. Technology WebSockets served as...

  10. Mars Atmospheric Aggregation System API

    Data.gov (United States)

    National Aeronautics and Space Administration — The {MAAS} API is an open source REST API built to help make it easier and more efficient to build interactive applications that want to utilize the wealth of...

  11. Data.gov CKAN API

    Data.gov (United States)

    General Services Administration — The data.gov catalog is powered by CKAN, a powerful open source data platform that includes a robust API. Please be aware that data.gov and the data.gov CKAN API...

  12. The File Sync Algorithm of the ownCloud Desktop Clients

    CERN Document Server

    CERN. Geneva

    2014-01-01

    The ownCloud desktop clients provide file syncing between desktop machines and the ownCloud server, available for the important desktop platforms. This presentation will give an overview of the sync algorithm used by the clients to provide a fast, reliable and robust syncing experience for the users. It will describe the phases a sync run will go through and how it is triggered. It also will provide an insight on the algorithms that decided if a file is uploaded, downloaded or even deleted on either on the local machine or in the cloud. Some examples of non obvious situations in file syncing will be described and discussed. As the ownCloud sync protocol is based on the open standard WebDAV the resulting challenges and the solutions will be illustrated. Finally a couple of frequently proposed enhancements will be reviewed and assed for the future development of the ownCloud server and syncing clients.

  13. Genome-wide analysis of signatures of selection in populations of African honey bees (Apis mellifera) using new web-based tools.

    Science.gov (United States)

    Fuller, Zachary L; Niño, Elina L; Patch, Harland M; Bedoya-Reina, Oscar C; Baumgarten, Tracey; Muli, Elliud; Mumoki, Fiona; Ratan, Aakrosh; McGraw, John; Frazier, Maryann; Masiga, Daniel; Schuster, Stephen; Grozinger, Christina M; Miller, Webb

    2015-07-10

    With the development of inexpensive, high-throughput sequencing technologies, it has become feasible to examine questions related to population genetics and molecular evolution of non-model species in their ecological contexts on a genome-wide scale. Here, we employed a newly developed suite of integrated, web-based programs to examine population dynamics and signatures of selection across the genome using several well-established tests, including F ST, pN/pS, and McDonald-Kreitman. We applied these techniques to study populations of honey bees (Apis mellifera) in East Africa. In Kenya, there are several described A. mellifera subspecies, which are thought to be localized to distinct ecological regions. We performed whole genome sequencing of 11 worker honey bees from apiaries distributed throughout Kenya and identified 3.6 million putative single-nucleotide polymorphisms. The dense coverage allowed us to apply several computational procedures to study population structure and the evolutionary relationships among the populations, and to detect signs of adaptive evolution across the genome. While there is considerable gene flow among the sampled populations, there are clear distinctions between populations from the northern desert region and those from the temperate, savannah region. We identified several genes showing population genetic patterns consistent with positive selection within African bee populations, and between these populations and European A. mellifera or Asian Apis florea. These results lay the groundwork for future studies of adaptive ecological evolution in honey bees, and demonstrate the use of new, freely available web-based tools and workflows ( http://usegalaxy.org/r/kenyanbee ) that can be applied to any model system with genomic information.

  14. Upon a Message-Oriented Trading API

    Directory of Open Access Journals (Sweden)

    Claudiu VINTE

    2010-01-01

    Full Text Available In this paper, we introduce the premises for a trading system application-programming interface (API based on a message-oriented middleware (MOM, and present the results of our research regarding the design and the implementation of a simulation-trading system employing a service-oriented architecture (SOA and messaging. Our research has been conducted with the aim of creating a simulation-trading platform, within the academic environment, that will provide both the foundation for future experiments with trading systems architectures, components, APIs, and the framework for research on trading strategies, trading algorithm design, and equity markets analysis tools. Mathematics Subject Classification: 68M14 (distributed systems.

  15. The API petroassist network

    International Nuclear Information System (INIS)

    Boortz, M.J.; Jardim, G.M.; Horn, S.A.; Disbennett, D.B.

    1993-01-01

    Past spill responses, such as those in the Exxon Valdez and American Trader incidents, demonstrated the value of companies volunteering their in-house experts and local knowledge to help other companies in spill response. The American Petroleum Institute (API) formed the PetroAssist Network to provide a means for oil companies to readily gain access to the expertise and communications equipment of other oil companies when needed for spill responses. An API work group developed the PetroAssist Network legal agreement and management and activation procedures. To minimize red tape and reduce the burden on members, existing systems were used whenever possible. The network became operational on January 1, 1992, with more than 40 members

  16. Fostering Second Language Oral Communication through Constructivist Interaction in Desktop Videoconferencing

    Science.gov (United States)

    Lee, Lina

    2007-01-01

    This article describes a classroom project using one-to-one desktop videoconferencing to enhance the development of second language (1.2) oral skills. Eighteen university students worked collaboratively with expert speakers to complete task-based activities. The author gathered data from video-recording samples, reflections, and oral interviews to…

  17. Writing Essays on a Laptop or a Desktop Computer: Does It Matter?

    Science.gov (United States)

    Ling, Guangming; Bridgeman, Brent

    2013-01-01

    To explore the potential effect of computer type on the Test of English as a Foreign Language-Internet-Based Test (TOEFL iBT) Writing Test, a sample of 444 international students was used. The students were randomly assigned to either a laptop or a desktop computer to write two TOEFL iBT practice essays in a simulated testing environment, followed…

  18. Multimodal Desktop Interaction: The Face –Object-Gesture–Voice Example

    DEFF Research Database (Denmark)

    Vidakis, Nikolas; Vlasopoulos, Anastasios; Kounalakis, Tsampikos

    2013-01-01

    This paper presents a natural user interface system based on multimodal human computer interaction, which operates as an intermediate module between the user and the operating system. The aim of this work is to demonstrate a multimodal system which gives users the ability to interact with desktop...

  19. Apis mellifera adansonii Latreille

    African Journals Online (AJOL)

    Une enquête "ethnoapicole" menée dans deux zones phytogéographiques du Burkina Faso a permis de recenser treize espèces végétales reparties en douze genres et huit familles botaniques qui sont utilisées par les apiculteurs traditionnels pour attirer les essaims d'Apis mellifera adansonii Latreille. Un meilleur ...

  20. Associated particle imaging (API)

    International Nuclear Information System (INIS)

    1998-05-01

    Associated Particle Imaging (API) is an active neutron probe technique that provides a 3-D image with elemental composition of the material under interrogation, and so occupies a unique niche in the interrogation of unknown objects. The highly penetrating nature of neutrons enables API to provide detailed information about targets of interest that are hidden from view. Due to the isotropic nature of the induced reactions, radiation detectors can be set on the same side of the object as the neutron source, so that the object can be interrogated from a single side. At the heat of the system is a small generator that produces a continuous, monoenergetic flux of neutrons. By measuring the trajectory of coincident alpha particles that are produced as part of the process, the trajectory of the neutron can be inferred. Interactions between a neutron and the material in its path often produce a gamma ray whose energy is characteristic of that material. When the gamma ray is detected, its energy is measured and combined with the trajectory information to produce a 3-D image of the composition of the object being interrogated. During the course of API development, a number of improvements have been made. A new, more rugged sealed Tube Neutron Generator (STNG) has been designed and fabricated that is less susceptible to radiation damage and better able to withstand the rigors of fielding than earlier designs. A specialized high-voltage power supply for the STNG has also been designed and built. A complete package of software has been written for the tasks of system calibration, diagnostics and data acquisition and analysis. A portable system has been built and field tested, proving that API can be taken out of the lab and into real-world situations, and that its performance in the field is equal to that in the lab

  1. Citrix XenApp 7.5 desktop virtualization solutions

    CERN Document Server

    Paul, Andy

    2014-01-01

    If you are a Citrix® engineer, a virtualization consultant, or an IT project manager with prior experience of using Citrix XenApp® and related technologies for desktop virtualization and want to further explore the power of XenApp® for flawless desktop virtualization, then this book is for you.

  2. Clinical evaluation of a desktop robotic assistant.

    Science.gov (United States)

    Hammel, J; Hall, K; Lees, D; Leifer, L; Van der Loos, M; Perkash, I; Crigler, R

    1989-01-01

    A desktop vocational assistant robotic workstation was evaluated by 24 high-level quadriplegics from the Palo Alto Veterans Affairs Spinal Cord Injury Center. The system is capable of performing daily living and vocational activities for individuals with high-level quadriplegia via voice control. Subjects were asked to use the robot to perform a repertoire of daily living activities, including preparing a meal and feeding themselves, washing their face, shaving, and brushing teeth. Pre- and post-test questionnaires, interviews, and observer assessments were conducted to determine the quality of the robot performance and the reaction of the disabled users toward this technology. Results of the evaluations were generally positive and demonstrated the usefulness of this technology in assisting high-level quadriplegics to perform daily activities and to gain a modicum of independence and privacy in their lives.

  3. Turbulence Visualization at the Terascale on Desktop PCs

    KAUST Repository

    Treib, M.

    2012-12-01

    Despite the ongoing efforts in turbulence research, the universal properties of the turbulence small-scale structure and the relationships between small-and large-scale turbulent motions are not yet fully understood. The visually guided exploration of turbulence features, including the interactive selection and simultaneous visualization of multiple features, can further progress our understanding of turbulence. Accomplishing this task for flow fields in which the full turbulence spectrum is well resolved is challenging on desktop computers. This is due to the extreme resolution of such fields, requiring memory and bandwidth capacities going beyond what is currently available. To overcome these limitations, we present a GPU system for feature-based turbulence visualization that works on a compressed flow field representation. We use a wavelet-based compression scheme including run-length and entropy encoding, which can be decoded on the GPU and embedded into brick-based volume ray-casting. This enables a drastic reduction of the data to be streamed from disk to GPU memory. Our system derives turbulence properties directly from the velocity gradient tensor, and it either renders these properties in turn or generates and renders scalar feature volumes. The quality and efficiency of the system is demonstrated in the visualization of two unsteady turbulence simulations, each comprising a spatio-temporal resolution of 10244. On a desktop computer, the system can visualize each time step in 5 seconds, and it achieves about three times this rate for the visualization of a scalar feature volume. © 1995-2012 IEEE.

  4. Integrated platform and API for electrophysiological data.

    Science.gov (United States)

    Sobolev, Andrey; Stoewer, Adrian; Leonhardt, Aljoscha; Rautenberg, Philipp L; Kellner, Christian J; Garbers, Christian; Wachtler, Thomas

    2014-01-01

    Recent advancements in technology and methodology have led to growing amounts of increasingly complex neuroscience data recorded from various species, modalities, and levels of study. The rapid data growth has made efficient data access and flexible, machine-readable data annotation a crucial requisite for neuroscientists. Clear and consistent annotation and organization of data is not only an important ingredient for reproducibility of results and re-use of data, but also essential for collaborative research and data sharing. In particular, efficient data management and interoperability requires a unified approach that integrates data and metadata and provides a common way of accessing this information. In this paper we describe GNData, a data management platform for neurophysiological data. GNData provides a storage system based on a data representation that is suitable to organize data and metadata from any electrophysiological experiment, with a functionality exposed via a common application programming interface (API). Data representation and API structure are compatible with existing approaches for data and metadata representation in neurophysiology. The API implementation is based on the Representational State Transfer (REST) pattern, which enables data access integration in software applications and facilitates the development of tools that communicate with the service. Client libraries that interact with the API provide direct data access from computing environments like Matlab or Python, enabling integration of data management into the scientist's experimental or analysis routines.

  5. Integrated platform and API for electrophysiological data

    Directory of Open Access Journals (Sweden)

    Andrey eSobolev

    2014-04-01

    Full Text Available Recent advancements in technology and methodology have led to growing amounts of increasingly complex neuroscience data recorded from various species, modalities, and levels of study. The rapid data growth has made efficient data access and flexible, machine-readable data annotation a crucial requisite for neuroscientists. Clear and consistent annotation and organization of data is not only an important ingredient for reproducibility of results and re-use of data, but also essential for collaborative research and data sharing. In particular, efficient data management and interoperability requires a unified approach that integrates data and metadata and provides a common way of accessing this information.In this paper we describe GNData, a data management platform for neurophysiological data. GNData provides a storage system based on a data representation that is suitable to organize data and metadata from any electrophysiological experiment, with a functionality exposed via a common application programming interface (API. Data representation and API structure are compatible with existing approaches for data and metadata representation in neurophysiology. The API implementation is based on the Representational State Transfer (REST pattern, which enables data access integration in software applications and facilitates the development of tools that communicate with the service. Client libraries that interact with the API provide direct data access from computing environments like Matlab or Python, enabling integration of data management into the scientist's experimental or analysis routines.

  6. Web API Fragility : How Robust is Your Web API Client

    NARCIS (Netherlands)

    Espinha, T.; Zaidman, A.; Gross, H.G.

    2014-01-01

    Web APIs provide a systematic and extensible approach for application-to-application interaction. A large number of mobile applications makes use of web APIs to integrate services into apps. Each Web API’s evolution pace is determined by their respective developer and mobile application developers

  7. Metodika návrhu RESTful API

    OpenAIRE

    Melena, Lukáš

    2017-01-01

    The subject of this thesis is RESTful API Design methodology. RESTful API is currently very popular type of API, but there is missing comprehensive guide how to create it. The target of this thesis is to design methodology of design RESTful API which fulfills all REST and Resource-oriented architecture principles defined by Fielding, Richardson and Ruby. The focus of the methodology is only on analysis and design of API. The first part is about description of RESTful API current situation, ma...

  8. Empirical Analysis of Server Consolidation and Desktop Virtualization in Cloud Computing

    Directory of Open Access Journals (Sweden)

    Bao Rong Chang

    2013-01-01

    Full Text Available Physical server transited to virtual server infrastructure (VSI and desktop device to virtual desktop infrastructure (VDI have the crucial problems of server consolidation, virtualization performance, virtual machine density, total cost of ownership (TCO, and return on investments (ROI. Besides, how to appropriately choose hypervisor for the desired server/desktop virtualization is really challenging, because a trade-off between virtualization performance and cost is a hard decision to make in the cloud. This paper introduces five hypervisors to establish the virtual environment and then gives a careful assessment based on C/P ratio that is derived from composite index, consolidation ratio, virtual machine density, TCO, and ROI. As a result, even though ESX server obtains the highest ROI and lowest TCO in server virtualization and Hyper-V R2 gains the best performance of virtual machine management; both of them however cost too much. Instead the best choice is Proxmox Virtual Environment (Proxmox VE because it not only saves the initial investment a lot to own a virtual server/desktop infrastructure, but also obtains the lowest C/P ratio.

  9. Learning Bing maps API

    CERN Document Server

    Sinani, Artan

    2013-01-01

    This is a practical, hands-on guide with illustrative examples, which will help you explore the vast universe of Bing maps.If you are a developer who wants to learn how to exploit the numerous features of Bing Maps then this book is ideal for you. It can also be useful for more experienced developers who wish to explore other areas of the APIs. It is assumed that you have some knowledge of JavaScript, HTML, and CSS. For some chapters a working knowledge of .Net and Visual Studio is also needed.

  10. Visual attention for a desktop virtual environment with ambient scent.

    Science.gov (United States)

    Toet, Alexander; van Schaik, Martin G

    2013-01-01

    In the current study participants explored a desktop virtual environment (VE) representing a suburban neighborhood with signs of public disorder (neglect, vandalism, and crime), while being exposed to either room air (control group), or subliminal levels of tar (unpleasant; typically associated with burned or waste material) or freshly cut grass (pleasant; typically associated with natural or fresh material) ambient odor. They reported all signs of disorder they noticed during their walk together with their associated emotional response. Based on recent evidence that odors reflexively direct visual attention to (either semantically or affectively) congruent visual objects, we hypothesized that participants would notice more signs of disorder in the presence of ambient tar odor (since this odor may bias attention to unpleasant and negative features), and less signs of disorder in the presence of ambient grass odor (since this odor may bias visual attention toward the vegetation in the environment and away from the signs of disorder). Contrary to our expectations the results provide no indication that the presence of an ambient odor affected the participants' visual attention for signs of disorder or their emotional response. However, the paradigm used in present study does not allow us to draw any conclusions in this respect. We conclude that a closer affective, semantic, or spatiotemporal link between the contents of a desktop VE and ambient scents may be required to effectively establish diagnostic associations that guide a user's attention. In the absence of these direct links, ambient scent may be more diagnostic for the physical environment of the observer as a whole than for the particular items in that environment (or, in this case, items represented in the VE).

  11. Evidence of Apis cerana Sacbrood virus Infection in Apis mellifera.

    Science.gov (United States)

    Gong, Hong-Ri; Chen, Xiu-Xian; Chen, Yan Ping; Hu, Fu-Liang; Zhang, Jiang-Lin; Lin, Zhe-Guang; Yu, Ji-Wei; Zheng, Huo-Qing

    2016-04-01

    Sacbrood virus(SBV) is one of the most destructive viruses in the Asian honeybee Apis cerana but is much less destructive in Apis mellifera In previous studies, SBV isolates infecting A. cerana(AcSBV) and SBV isolates infecting A. mellifera(AmSBV) were identified as different serotypes, suggesting a species barrier in SBV infection. In order to investigate this species isolation, we examined the presence of SBV infection in 318A. mellifera colonies and 64A. cerana colonies, and we identified the genotypes of SBV isolates. We also performed artificial infection experiments under both laboratory and field conditions. The results showed that 38A. mellifera colonies and 37A. cerana colonies were positive for SBV infection. Phylogenetic analysis based on RNA-dependent RNA polymerase (RdRp) gene sequences indicated that A. cerana isolates and most A. mellifera isolates formed two distinct clades but two strains isolated fromA. mellifera were clustered with theA. cerana isolates. In the artificial-infection experiments, AcSBV negative-strand RNA could be detected in both adult bees and larvae ofA. mellifera, although there were no obvious signs of the disease, demonstrating the replication of AcSBV inA. mellifera Our results suggest that AcSBV is able to infectA. melliferacolonies with low prevalence (0.63% in this study) and pathogenicity. This work will help explain the different susceptibilities ofA. cerana and A. melliferato sacbrood disease and is potentially useful for guiding beekeeping practices. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  12. Training Capabilities of Wearable and Desktop Simulator Interfaces

    Science.gov (United States)

    2011-11-01

    Intrinsic Motivation Inventory) than the control group, with no differences being found between the desktop and wearable groups.  The Desktop and...associated with the use of the simulator for training, with each of these scales ranging from 0 - 500. Intrinsic Motivation Inventory (IMI). The IMI...subscale of the Presence Questionnaire (r = .350, p = .001) as well as the Perceived Competence subscale of the Intrinsic Motivation Inventory (r

  13. Microsoft Virtualization Master Microsoft Server, Desktop, Application, and Presentation Virtualization

    CERN Document Server

    Olzak, Thomas; Boomer, Jason; Keefer, Robert M

    2010-01-01

    Microsoft Virtualization helps you understand and implement the latest virtualization strategies available with Microsoft products. This book focuses on: Server Virtualization, Desktop Virtualization, Application Virtualization, and Presentation Virtualization. Whether you are managing Hyper-V, implementing desktop virtualization, or even migrating virtual machines, this book is packed with coverage on all aspects of these processes. Written by a talented team of Microsoft MVPs, Microsoft Virtualization is the leading resource for a full installation, migration, or integration of virtual syste

  14. A Review on Genomics APIs

    Directory of Open Access Journals (Sweden)

    Rajeswari Swaminathan

    2016-01-01

    Full Text Available The constant improvement and falling prices of whole human genome Next Generation Sequencing (NGS has resulted in rapid adoption of genomic information at both clinics and research institutions. Considered together, the complexity of genomics data, due to its large volume and diversity along with the need for genomic data sharing, has resulted in the creation of Application Programming Interface (API for secure, modular, interoperable access to genomic data from different applications, platforms, and even organizations. The Genomics APIs are a set of special protocols that assist software developers in dealing with multiple genomic data sources for building seamless, interoperable applications leading to the advancement of both genomic and clinical research. These APIs help define a standard for retrieval of genomic data from multiple sources as well as to better package genomic information for integration with Electronic Health Records. This review covers three currently available Genomics APIs: a Google Genomics, b SMART Genomics, and c 23andMe. The functionalities, reference implementations (if available and authentication protocols of each API are reviewed. A comparative analysis of the different features across the three APIs is provided in the Discussion section. Though Genomics APIs are still under active development and have yet to reach widespread adoption, they hold the promise to make building of complicated genomics applications easier with downstream constructive effects on healthcare.

  15. Bluetooth API Implementation into Android

    Directory of Open Access Journals (Sweden)

    Konev Sergey

    2017-01-01

    Full Text Available Bluetooth is a popular method of communication between devices. Many smartphones today have the capability to communicate using Bluetooth. Android developers sometimes need to use Bluetooth in their projects. Android OS provides a powerful API for Bluetooth that allows to simplify scanning the environment for devices, pairing and connecting, data transfer between devices and more. However, utilizing the Bluetooth API can be difficult for first-time users. The objective of this article is to demonstrate the key points of implementing Bluetooth API in the Android application.

  16. Intro to the Zotero API

    Directory of Open Access Journals (Sweden)

    Amanda Morton

    2013-04-01

    Full Text Available In this lesson, you’ll learn how to use python with the Zotero API to interact with your Zotero library. The Zotero API is a powerful interface that would allow you to build a complete Zotero client from scratch if you so desired. But like most APIs, it works in small, discrete steps, so we have to build our way up to the complicated requests we might want to use to access our Zotero libraries. But this incremental building gives us plenty of time to learn as we go along.

  17. Schema crawled API documentation exploration

    OpenAIRE

    Bakkeli, Nicolai

    2017-01-01

    Åpne API blir stadig mer utbredt som fører til at utviklere kan benytte mye tid i å lese dokumentasjon for å finne et passende alternativ. Tesen beskriver en design som kan benyttes for å danne et sett med hjelpemidler som har til hensikt å redusere unødvendige alternativ av API for brukeren. Dette gjøres via en web crawler som går gjennom API dokumentasjon samt en behandler av datamengdene som spesifikt benytter XML Schema for å finne retur formet til APIene den støter på. Resultatene listes...

  18. Practical Implementation of 10 Rules for Writing REST APIs

    Directory of Open Access Journals (Sweden)

    Jiri Hradil

    2017-01-01

    Full Text Available This paper shows a practical implementation of “10 Rules for Writing REST APIs introduced in the article” (Hradil, 2016. The application is done in Invoice Home (Wikilane, 2016, an invoicing web application for small business and entrepreneurs available world-wide. The API is implemented in JSON hypermedia format (ECMA International, 2016 and with Ruby on Rails framework (Hansson, 2016. The main purpose of the API is to allow connection of Invoice Home with external systems and offer Invoice Home data in simpler format compared to the current HTML format of the full-stack web application. The paper could be also used as a basic template or pattern for any other implementation of the JSON API in any web-based application.

  19. Validation of the Parlay API through prototyping

    OpenAIRE

    Hellenthal, J.W.; Planken, F.J.M.; Wegdam, M.

    2001-01-01

    The desire within the telecommunications world for new and faster business growth has been a major drive towards the development of open network API. Over the past 7 years several (semi) standardization groups have announced work on network API, including TINA-C, JAIN, IEEE P1520, INforum, 3GPP, JAIN, Parlay. The Parlay group seems most successful in attracting industry awareness with their API, called the Parlay API. The rational behind the Parlay API is that it attracts innovation from thir...

  20. Analytical Hierarchy Process for the selection of strategic alternatives for introduction of infrastructure virtual desktop infrastructure in the university

    Directory of Open Access Journals (Sweden)

    Katerina A. Makoviy

    2017-12-01

    Full Text Available The task of choosing a strategy for implementing the virtual desktop infrastructure into the IT infrastructure of the university is considered. The infrastructure of virtual desktops is a technology that provides centralization of management of client workplaces, increase the service life of computers in classrooms. The analysis of strengths and weaknesses, threats and opportunities for introducing virtualization in the university. Alternatives to implementation based on the results of the pilot project have been developed. To obtain quantitative estimates in the SWOT - analysis of the pilot project, the analytical hierarchy process is used. The analysis of implementation of the pilot project by experts is carried out and the integral value of quantitative estimates of various alternatives is generated. The combination of the analytical hierarchy process and SWOT - analysis allows you to choose the optimal strategy for implementing desktop virtualization.

  1. Analyst productivity and the RELAP5 desktop analyzer

    International Nuclear Information System (INIS)

    Beelman, R.J.

    1989-01-01

    Historically, the productivity of a numerical reactor safety analyst has been hampered by several factors: poor mainframe computer turnaround for problem setup, checkout, and initialization; limited mainframe CPU allocation, accessibility and availability for transient advancement; lost or delayed output; and difficulty assimilating numerical results. Clearly, an economical engineering workstation capable of running RELAP5 interactively, and of simultaneously displaying the results in a coherent graphic fashion as they are produced, would alleviate many of these concerns. The RELAP5 desktop analyzer (RDA) is such a workstation. Although not yet capable of real-time simulation, the RDA will nevertheless reduce analysis costs and enhance analyst productivity since analysis cannot be done in real time anyway. The RDA is a microcomputer-based reactor transient simulation, visualization, and analysis tool developed at the Idaho National Engineering Laboratory (INEL) to assist an analyst in simulating and evaluating the transient behavior of nuclear power plants. The RDA integrates RELAP5 advanced best-estimate engineering simulation capabilities with on-line computer graphics routines allowing interactive reactor plant transient simulation and on-line analysis of results, or replay of past simulations, by means of graphic displays

  2. Perception Analysis of Desktop and Mobile Service Website

    Directory of Open Access Journals (Sweden)

    Rizqiyatul Khoiriyah

    2016-12-01

    Full Text Available The research was conducted as a qualitative study of the website to deeper explore and examine the analysis of user perception of desktop and mobile website services. This research reviewed about user perception of desktop and mobile service website used by using qualitative methods adapted to WebQual and User Experience approach. This qualitative research refered to the theoretical reference written by Creswell (2014. The expected outcome is to know the user perceptions of the available services and information in the website along with the possibility of desktop and mobile gap arising from differences in the two services. These results can be used as a service model on the website of the user experience.

  3. A desktop 3D printer with dual extruders to produce customised electronic circuitry

    Science.gov (United States)

    Butt, Javaid; Onimowo, Dominic Adaoiza; Gohrabian, Mohammed; Sharma, Tinku; Shirvani, Hassan

    2018-03-01

    3D printing has opened new horizons for the manufacturing industry in general, and 3D printers have become the tools for technological advancements. There is a huge divide between the pricing of industrial and desktop 3D printers with the former being on the expensive side capable of producing excellent quality products and latter being on the low-cost side with moderate quality results. However, there is a larger room for improvements and enhancements for the desktop systems as compared to the industrial ones. In this paper, a desktop 3D printer called Prusa Mendel i2 has been modified and integrated with an additional extruder so that the system can work with dual extruders and produce bespoke electronic circuits. The communication between the two extruders has been established by making use of the In-Chip Serial Programming port on the Arduino Uno controlling the printer. The biggest challenge is to control the flow of electric paint (to be dispensed by the new extruder) and CFD (Computational Fluid Dynamics) analysis has been carried out to ascertain the optimal conditions for proper dispensing. The final product is a customised electronic circuit with the base of plastic (from the 3D printer's extruder) and electronic paint (from the additional extruder) properly dispensed to create a live circuit on a plastic platform. This low-cost enhancement to a desktop 3D printer can provide a new prospect to produce multiple material parts where the additional extruder can be filled with any material that can be properly dispensed from its nozzle.

  4. An Introduction to Version Control Using GitHub Desktop

    Directory of Open Access Journals (Sweden)

    Daniel van Strien

    2016-06-01

    Full Text Available In this lesson you will be introduced to the basics of version control, understand why it is useful and implement basic version control for a plain text document using GitHub Desktop. By the end of this lesson you should understand: * what version control is and why it can be useful * the differences between Git and GitHub * how to implement version control using ‘GitHub Desktop,’ a Graphical User Interface for GitHub * be aware of other resources that will help you implement version control in your academic writing

  5. The Virtual Desktop: Options and Challenges in Selecting a Secure Desktop Infrastructure Based on Virtualization

    Science.gov (United States)

    2011-10-01

    34 6.1.2 Citrix ...mature hosted solution for clients; Citrix – Citrix provides an end-to-end virtualization solution for enterprises, and has recently released a...4.0 have received EAL-4 certifications3. Detailed information about VMware products can be found at: http://www.vmware.com 6.1.2 Citrix Citrix

  6. Automated Ply Inspection (API) for AFP Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Automated Ply Inspection (API) system autonomously inspects layups created by high speed automated fiber placement (AFP) machines. API comprises a high accuracy...

  7. Adaptive runtime for a multiprocessing API

    Science.gov (United States)

    Antao, Samuel F.; Bertolli, Carlo; Eichenberger, Alexandre E.; O'Brien, John K.

    2016-11-15

    A computer-implemented method includes selecting a runtime for executing a program. The runtime includes a first combination of feature implementations, where each feature implementation implements a feature of an application programming interface (API). Execution of the program is monitored, and the execution uses the runtime. Monitor data is generated based on the monitoring. A second combination of feature implementations are selected, by a computer processor, where the selection is based at least in part on the monitor data. The runtime is modified by activating the second combination of feature implementations to replace the first combination of feature implementations.

  8. The Web as an API.

    Energy Technology Data Exchange (ETDEWEB)

    Roman, J. H. (Jorge H.)

    2001-01-01

    As programmers we have worked with many Application Development Interface API development kits. They are well suited for interaction with a particular system. A vast source of information can be made accessible by using the http protocol through the web as an API. This setup has many advantages including the vast knowledge available on setting web servers and services. Also, these tools are available on most hardware and operating system combinations. In this paper I will cover the various types of systems that can be developed this way, their advantages and some drawbacks of this approach. Index Terms--Application Programmer Interface, Distributed applications, Hyper Text Transfer Protocol, Web.

  9. The Dutch xAPI Experience

    OpenAIRE

    Berg, Alan; Scheffel, Maren; Drachsler, Hendrik; Ternier, Stefaan; Specht, Marcus

    2017-01-01

    We present the collected experiences since 2012 of the Dutch Special Interest Group (SIG) for Learning Analytics in the application of the xAPI standard. We have been experimenting and exchanging best practices around the application of xAPI in various contexts. The practices include di fferent design patterns centered around Learning Record Stores. We present three projects that apply xAPI in very diff erent ways and publish a consistent set of xAPI recipes.

  10. Telecollaborative Desktop-Videoconferencing Exchange: The Case of Mark

    Science.gov (United States)

    Martin, Véronique

    2014-01-01

    This presentation is a case study of the Intercultural Communicative Competence (ICC) development of Mark, one of ten American students engaged in a desktop-videoconferencing telecollaborative exchange with a class of French students. Due in part to its inherent complexity, this context has not been widely researched. To observe ICC development, I…

  11. Versatile Desktop Experiment Module (DEMo) on Heat Transfer

    Science.gov (United States)

    Minerick, Adrienne R.

    2010-01-01

    This paper outlines a new Desktop Experiment Module (DEMo) engineered for a chemical engineering junior-level Heat Transfer course. This new DEMo learning tool is versatile, fairly inexpensive, and portable such that it can be positioned on student desks throughout a classroom. The DEMo system can illustrate conduction of various materials,…

  12. Laevo: A Temporal Desktop Interface for Integrated Knowledge Work

    DEFF Research Database (Denmark)

    Jeuris, Steven; Houben, Steven; Bardram, Jakob

    2014-01-01

    states and transitions of an activity. The life cycle is used to inform the design of Laevo, a temporal activity-centric desktop interface for personal knowledge work. Laevo allows users to structure work within dedicated workspaces, managed on a timeline. Through a centralized notification system which...

  13. Hydropower Regulatory and Permitting Information Desktop (RAPID) Toolkit

    Energy Technology Data Exchange (ETDEWEB)

    Levine, Aaron L [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-12-19

    Hydropower Regulatory and Permitting Information Desktop (RAPID) Toolkit presentation from the WPTO FY14-FY16 Peer Review. The toolkit is aimed at regulatory agencies, consultants, project developers, the public, and any other party interested in learning more about the hydropower regulatory process.

  14. EPA Region 8, Memo on Desktop Printer Ink Cartridges Policy & Voluntary Printer Turn-in

    Science.gov (United States)

    This memo requests EPA Region 8 users to voluntarily turn-in their desktop printers and notifies users of the Region 8 policy to not provide maintenance or ink and toner cartridges for desktop printers.

  15. MedlinePlus® Everywhere: Access from Your Phone, Tablet or Desktop

    Science.gov (United States)

    ... responsivefull.html MedlinePlus® Everywhere: Access from Your Phone, Tablet or Desktop To use the sharing features on ... provide a consistent user experience from a desktop, tablet, or phone. All users, regardless of how they ...

  16. New generation of 3D desktop computer interfaces

    Science.gov (United States)

    Skerjanc, Robert; Pastoor, Siegmund

    1997-05-01

    Today's computer interfaces use 2-D displays showing windows, icons and menus and support mouse interactions for handling programs and data files. The interface metaphor is that of a writing desk with (partly) overlapping sheets of documents placed on its top. Recent advances in the development of 3-D display technology give the opportunity to take the interface concept a radical stage further by breaking the design limits of the desktop metaphor. The major advantage of the envisioned 'application space' is, that it offers an additional, immediately perceptible dimension to clearly and constantly visualize the structure and current state of interrelations between documents, videos, application programs and networked systems. In this context, we describe the development of a visual operating system (VOS). Under VOS, applications appear as objects in 3-D space. Users can (graphically connect selected objects to enable communication between the respective applications. VOS includes a general concept of visual and object oriented programming for tasks ranging from, e.g., low-level programming up to high-level application configuration. In order to enable practical operation in an office or at home for many hours, the system should be very comfortable to use. Since typical 3-D equipment used, e.g., in virtual-reality applications (head-mounted displays, data gloves) is rather cumbersome and straining, we suggest to use off-head displays and contact-free interaction techniques. In this article, we introduce an autostereoscopic 3-D display and connected video based interaction techniques which allow viewpoint-depending imaging (by head tracking) and visually controlled modification of data objects and links (by gaze tracking, e.g., to pick, 3-D objects just by looking at them).

  17. A knowledge discovery object model API for Java

    Directory of Open Access Journals (Sweden)

    Jones Steven JM

    2003-10-01

    Full Text Available Abstract Background Biological data resources have become heterogeneous and derive from multiple sources. This introduces challenges in the management and utilization of this data in software development. Although efforts are underway to create a standard format for the transmission and storage of biological data, this objective has yet to be fully realized. Results This work describes an application programming interface (API that provides a framework for developing an effective biological knowledge ontology for Java-based software projects. The API provides a robust framework for the data acquisition and management needs of an ontology implementation. In addition, the API contains classes to assist in creating GUIs to represent this data visually. Conclusions The Knowledge Discovery Object Model (KDOM API is particularly useful for medium to large applications, or for a number of smaller software projects with common characteristics or objectives. KDOM can be coupled effectively with other biologically relevant APIs and classes. Source code, libraries, documentation and examples are available at http://www.bcgsc.ca/bioinfo/software.

  18. Full-scope nuclear training simulator -brought to the desktop

    International Nuclear Information System (INIS)

    LaPointe, D.J.; Manz, A.; Hall, G.S.

    1997-01-01

    RighTSTEP is a suite of simulation software which has been initially designed to facilitate upgrade of Ontario Hydro's full-scope simulators, but is also adaptable to a variety of other roles. it is presently being commissioned at Bruch A Training Simulator and has seen preliminary use in desktop and classroom roles. Because of the flexibility of the system, we anticipate it will see common use in the corporation for full-scope simulation roles. A key reason for developing RighTSTEP (Real Time Simulator Technology Extensible and Portable) was the need to modernize and upgrade the full-scope training simulator while protecting the investment in modelling code. This modelling code represents the end product of 18 years of evolution from the beginning of its development in 1979. Bringing this modelling code to a modern and more useful framework - the combination of simulator host, operating system, and simulator operating system - also could provide many spin-off benefits. The development (and first implementation) of the righTSTEP system was cited for saving the corporation 5.6M$ and was recognized by a corporate New Technology Award last year. The most important spin-off from this project has been the desktop version of the full-scope simulator. The desktop simulator uses essentially the same software as does its full-scope counterpart, and may be used for a variety of new purposes. Classroom and individual simulator training can now be easily accommodated since a desktop simulator is both affordable and relatively ease to use. Further, a wide group of people can be trained using the desktop simulator: by contrast the full-scope simulators were almost exclusively devoted to front-line operating staff. The desktop is finding increasing use in support of engineering applications, resulting from its easy accessibility, breadth of station systems represented, and tools for analysis and viewing. As further plant models are made available on the new simulator platform and

  19. TOPCAT: Desktop Exploration of Tabular Data for Astronomy and Beyond

    Directory of Open Access Journals (Sweden)

    Mark Taylor

    2017-06-01

    Full Text Available TOPCAT, the Tool for OPerations on Catalogues And Tables, is an interactive desktop application for retrieval, analysis and manipulation of tabular data, offering a powerful and flexible range of interactive visualization options amongst other features. Its visualization capabilities focus on enabling interactive exploration of large static local tables—millions of rows and hundreds of columns can easily be handled on a standard desktop or laptop machine, and various options are provided for meaningful graphical representation of such large datasets. TOPCAT has been developed in the context of astronomy, but many of its features are equally applicable to other domains. The software, which is free and open source, is written in Java, and the underlying high-performance visualisation library is suitable for re-use in other applications.

  20. Feasibility of Bioprinting with a Modified Desktop 3D Printer.

    Science.gov (United States)

    Goldstein, Todd A; Epstein, Casey J; Schwartz, John; Krush, Alex; Lagalante, Dan J; Mercadante, Kevin P; Zeltsman, David; Smith, Lee P; Grande, Daniel A

    2016-12-01

    Numerous studies have shown the capabilities of three-dimensional (3D) printing for use in the medical industry. At the time of this publication, basic home desktop 3D printer kits can cost as little as $300, whereas medical-specific 3D bioprinters can cost more than $300,000. The purpose of this study is to show how a commercially available desktop 3D printer could be modified to bioprint an engineered poly-l-lactic acid scaffold containing viable chondrocytes in a bioink. Our bioprinter was used to create a living 3D functional tissue-engineered cartilage scaffold. In this article, we detail the design, production, and calibration of this bioprinter. In addition, the bioprinted cells were tested for viability, proliferation, biochemistry, and gene expression; these tests showed that the cells survived the printing process, were able to continue dividing, and produce the extracellular matrix expected of chondrocytes.

  1. Multi-memetic Mind Evolutionary Computation Algorithm for Loosely Coupled Systems of Desktop Computers

    Directory of Open Access Journals (Sweden)

    M. K. Sakharov

    2015-01-01

    Full Text Available This paper deals with the development and software implementation of the hybrid multi-memetic algorithm for distributed computing systems. The main algorithm is based on the modification of MEC algorithm proposed by the authors. The multi-memetic algorithm utilizes three various local optimization methods. Software implementation was developed using MPI for Python and tested on a grid network made of twenty desktop computers. Performance of the proposed algorithm and its software implementation was investigated using multi-dimensional multi-modal benchmark functions from CEC’14.

  2. Limited impacts of truck-based ultra-low-volume applications of mosquito adulticides on mortality in honey bees (Apis mellifera).

    Science.gov (United States)

    Rinkevich, F D; Margotta, J W; Pokhrel, V; Walker, T W; Vaeth, R H; Hoffman, W C; Fritz, B K; Danka, R G; Rinderer, T E; Aldridge, R L; Linthicum, K J; Ottea, J A; Healy, K B

    2017-12-01

    Adulticides applied against mosquitoes can reduce vector populations during times of high arbovirus transmission. However, impacts of these insecticides on pollinators and other non-target organisms are of concern to mosquito control professionals, beekeepers and others. We evaluated mortality of Culex quinquefasciatus and Apis mellifera when caged insects were exposed to low and high label rates of four common adulticides (Aqua-Pursuit™ [permethrin], Duet® [prallethrin + sumithrin], Fyfanon® [malathion] and Scourge® [resmethrin]) at six distances up to 91.4 m from a truck-mounted ultra-low-volume sprayer. Honey bee mortality was both absolutely low (61 m had limited impacts on honey bee mortality while providing effective mosquito control.

  3. Desktop Social Science: Coming of Age.

    Science.gov (United States)

    Dwyer, David C.; And Others

    Beginning in 1985, Apple Computer, Inc. and several school districts began a collaboration to examine the impact of intensive computer use on instruction and learning in K-12 classrooms. This paper follows the development of a Macintosh II-based management and retrieval system for text data undertaken to store and retrieve oral reflections of…

  4. Macelignan inhibits bee pathogenic fungi Ascophaera apis growth through HOG1 pathway

    Directory of Open Access Journals (Sweden)

    Y.K. Shin

    2016-01-01

    Full Text Available Ascosphaera apis is a bee pathogen that causes bee larvae infection disease, to which treatment is not yet well investigated. The aim of this study was to investigate antifungal susceptibility in vitro against A. apis and to identify a new antifungal agent for this pathogen through minimal inhibitory concentration (MIC assay and western blot analysis. Macelignan had 1.56 and 3.125 μg/mL MIC against A. apis after 24 and 48 h, respectively, exhibiting the strongest growth inhibition against A. apis among the tested compounds (corosolic acid, dehydrocostus lactone, loganic acid, tracheloside, fangchinoline and emodin-8-O-β-D-glucopyranoside. Furthermore, macelignan showed a narrow-ranged spectrum against various fungal strains without any mammalian cell cytotoxicity. In spite of miconazole having powerful broad-ranged anti-fungal activity including A. apis, it demonstrated strong cytotoxicity. Therefore, even if macelignan alone was effective as an antifungal agent to treat A. apis, combined treatment with miconazole was more useful to overcome toxicity, drug resistance occurrence and cost effectiveness. Finally, HOG1 was revealed as a target molecule of macelignan in the anti-A. apis activity by inhibiting phosphorylation using S. cerevisiae as a model system. Based on our results, macelignan, a food-grade antimicrobial compound, would be an effective antifungal agent against A. apis infection in bees.

  5. Influence of humidity on the phase behavior of API/polymer formulations.

    Science.gov (United States)

    Prudic, Anke; Ji, Yuanhui; Luebbert, Christian; Sadowski, Gabriele

    2015-08-01

    Amorphous formulations of APIs in polymers tend to absorb water from the atmosphere. This absorption of water can induce API recrystallization, leading to reduced long-term stability during storage. In this work, the phase behavior of different formulations was investigated as a function of relative humidity. Indomethacin and naproxen were chosen as model APIs and poly(vinyl pyrrolidone) (PVP) and poly(vinyl pyrrolidone-co-vinyl acetate) (PVPVA64) as excipients. The formulations were prepared by spray drying. The water sorption in pure polymers and in formulations was measured at 25°C and at different values of relative humidity (RH=25%, 50% and 75%). Most water was absorbed in PVP-containing systems, and water sorption was decreasing with increasing API content. These trends could also be predicted in good agreement with the experimental data using the thermodynamic model PC-SAFT. Furthermore, the effect of absorbed water on API solubility in the polymer and on the glass-transition temperature of the formulations was predicted with PC-SAFT and the Gordon-Taylor equation, respectively. The absorbed water was found to significantly decrease the API solubility in the polymer as well as the glass-transition temperature of the formulation. Based on a quantitative modeling of the API/polymer phase diagrams as a function of relative humidity, appropriate API/polymer compositions can now be selected to ensure long-term stable amorphous formulations at given storage conditions. Copyright © 2015 Elsevier B.V. All rights reserved.

  6. Virtual reality exposure therapy: 150-degree screen to desktop PC.

    Science.gov (United States)

    Tichon, Jennifer; Banks, Jasmine

    2006-08-01

    Virtual reality exposure therapy (VRET) developed using immersive or semi-immersive virtual environments present a usability problem for practitioners. To meet practitioner requirements for lower cost and portability VRET programs must often be ported onto desktop environments such as the personal computer (PC). However, success of VRET has been shown to be linked to presence, and the environment's ability to evoke the same reactions and emotions as a real experience. It is generally accepted that high-end virtual environments (VEs) are more immersive than desktop PCs, but level of immersion does not always predict level of presence. This paper reports on the impact on presence of porting a therapeutic VR application for schizophrenia from the initial research environment of a semi-immersive curved screen to PC. Presence in these two environments is measured both introspectively and across a number of causal factors thought to underlie the experience of presence. Results show that the VR exposure program successfully made users feel they were "present" in both platforms. While the desktop PC achieved higher scores on presence across causal factors participants reported they felt more present in the curved screen environment. While comparison of the two groups was statistically significant for the PQ but not for the IPQ, subjective reports of experiences in the environments should be considered in future research as the success of VRET relies heavily on the emotional response of patients to the therapeutic program.

  7. Pathogen detection and gut bacteria identification in Apis cerana ...

    African Journals Online (AJOL)

    acer

    other lactic acid bacteria, were isolated from larvae and adult workers, but gave conflicting preliminary identities based on their biochemistry-morphology versus sequence analysis of a partial fragment (1.4 kb) of their 16S rRNA. Key words: Apis cerana indica, bee pathogens, gut bacteria, multiplex polymerase chain ...

  8. Desktop NMR for structure elucidation and identification of strychnine adulteration.

    Science.gov (United States)

    Singh, Kawarpal; Blümich, Bernhard

    2017-05-02

    Elucidating the structure of complex molecules is difficult at low magnetic fields due to the overlap of different peak multiplets and second-order coupling effects. This is even more challenging for rigid molecules with small chemical shift differences and with prochiral centers. Since low-field NMR spectroscopy is sometimes presumed as restricted to the analysis of only small and simple molecules, this paper aims at countering this misconception: it demonstrates the use of low-field NMR spectroscopy in chemical forensics for identifying strychnine and its counterions by exploring the chemical shift as a signature in different 1D 1 H and 13 C experiments. Hereby the applied methodologies combine various 1D and 2D experiments such as 1D 1 H, 13 C, DEPT, and 2D COSY, HETCOR, HSQC, HMBC and J-resolved spectroscopy to elucidate the molecular structure and skeleton of strychnine at 1 Tesla. Strychnine is exemplified here, because it is a basic precursor in the chemistry of natural products and is employed as a chemical weapon and as a doping agent in sports including the Olympics. In our study, the molecular structure of the compound could be identified either with a 1D experiment at high magnetic field or with HMBC and HSQC experiments at 1 T. In conclusion, low-field NMR spectroscopy enables the chemical elucidation of the strychnine structure through a simple click with a computer mouse. In situations where a high-field NMR spectrometer is unavailable, compact NMR spectrometers can nevertheless generate knowledge of the structure, important for identifying the different chemical reaction mechanisms associated with the molecule. Desktop NMR is a cost-effective viable option in chemical forensics. It can prove adulteration and identify the origin of different strychnine salts, in particular, the strychnine free base, strychnine hemisulphate and strychnine hydrochloride. The chemical shift signatures report the chemical structure of the molecules due to the impact of

  9. Building API manufacturing in South Africa

    CSIR Research Space (South Africa)

    Loots, Glaudina

    2017-10-01

    Full Text Available 2006 SA government concerned about the security of supply of ARV APIs & high cost to the fiscus. • Initiated concerted effort to attract global API to establish operations in the country. • Despite incentives such as grants, tax rebates, co... of equipment (glass lined vessels, valves, instruments, purification units, etc) due to lack of local engineering and manufacturing capabilities – dire shortage of process and project engineers & construction companies experienced in API (cGMP) plant...

  10. REST API : Implementation with Flask-Python

    OpenAIRE

    Alemu, Musse Bekabil

    2014-01-01

    Author Musse Alemu Year 2014 Supervisor Mattila Erkki Commissioned by Oy Aurora Data and Systems Ltd. Title of thesis REST API No. of pages + app. 44 + 2 Communication between various systems is common in the technology world. Thus, this thesis report discussed one of the popular means of communication, REST API. Additionally, it described the six basic constraints of REST conjointly to HATEOAS constraint. Furthermore, it observed all the good advantages REST API has over...

  11. DIaaS: Resource Management System for the Intra-Cloud with On-Premise Desktops

    Directory of Open Access Journals (Sweden)

    Hyun-Woo Kim

    2017-01-01

    Full Text Available Infrastructure as a service with desktops (DIaaS based on the extensible mark-up language (XML is herein proposed to utilize surplus resources. DIaaS is a traditional surplus-resource integrated management technology. It is designed to provide fast work distribution and computing services based on user service requests as well as storage services through desktop-based distributed computing and storage resource integration. DIaaS includes a nondisruptive resource service and an auto-scalable scheme to enhance the availability and scalability of intra-cloud computing resources. A performance evaluation of the proposed scheme measured the clustering performance time for surplus resource utilization. The results showed improvement in computing and storage services in a connection of at least two computers compared to the traditional method for high-availability measurement of nondisruptive services. Furthermore, an artificial server error environment was used to create a clustering delay for computing and storage services and for nondisruptive services. It was compared to the Hadoop distributed file system (HDFS.

  12. AKTIVITAS ANTIOKSIDAN DAN EFEK HEPATOPROTEKTIF DAUN BAKAU API-API PUTIH

    Directory of Open Access Journals (Sweden)

    safrina dyah hardiningtyas

    2014-07-01

    Full Text Available Penelitian ini bertujuan untuk mendapatkan ekstrak kasar daun api-api putih yang memiliki aktivitas antioksidan terbaik, menentukan kandungan fitokimia dan efek Hepatoprotektif ekstrak kasar yang dipilih secara in vivo. Daun api-api putih diekstrak menggunakan tiga jenis pelarut, yakni metanol, etil asetat dan n-heksana. Dalam uji in vivo dilakukan evaluasi terhadap kadar malondialdehid (MDA, enzim aspartat transaminase (AST, enzim alanin transaminase (ALT, dan histopatologi. Hasil penelitian menunjukkan bahwa ekstraksi daun api-api putih dengan pelarut etil asetat menghasilkan aktivitas antioksidan terbaik dengan kandungan fitokimia terdiri dari flavonoid dan steroid/triterpenoid. Pemberian ekstrak etil asetat daun api-api putih pada tikus yang telah diinduksi CCl4 dapat menormalkan berbagai parameter biokimia stres oksidatif (kadar MDA, AST, dan ALT dibandingkan dengan standar Silymarin. Ekstrak daun api-api putih berpotensi untuk melindungi hati tikus dari kerusakan oksidatif yang diinduksi CCl4. Efek Hepatoprotektif ekstrak daun api-api putih berkorelasi dengan aktivitas antioksidannya.Kata kunci: antioksidan, Avicennia marina, ekstrak, hepatoprotektor

  13. The Ruby UCSC API: accessing the UCSC genome database using Ruby

    Directory of Open Access Journals (Sweden)

    Mishima Hiroyuki

    2012-09-01

    Full Text Available Abstract Background The University of California, Santa Cruz (UCSC genome database is among the most used sources of genomic annotation in human and other organisms. The database offers an excellent web-based graphical user interface (the UCSC genome browser and several means for programmatic queries. A simple application programming interface (API in a scripting language aimed at the biologist was however not yet available. Here, we present the Ruby UCSC API, a library to access the UCSC genome database using Ruby. Results The API is designed as a BioRuby plug-in and built on the ActiveRecord 3 framework for the object-relational mapping, making writing SQL statements unnecessary. The current version of the API supports databases of all organisms in the UCSC genome database including human, mammals, vertebrates, deuterostomes, insects, nematodes, and yeast. The API uses the bin index—if available—when querying for genomic intervals. The API also supports genomic sequence queries using locally downloaded *.2bit files that are not stored in the official MySQL database. The API is implemented in pure Ruby and is therefore available in different environments and with different Ruby interpreters (including JRuby. Conclusions Assisted by the straightforward object-oriented design of Ruby and ActiveRecord, the Ruby UCSC API will facilitate biologists to query the UCSC genome database programmatically. The API is available through the RubyGem system. Source code and documentation are available at https://github.com/misshie/bioruby-ucsc-api/ under the Ruby license. Feedback and help is provided via the website at http://rubyucscapi.userecho.com/.

  14. The Ruby UCSC API: accessing the UCSC genome database using Ruby.

    Science.gov (United States)

    Mishima, Hiroyuki; Aerts, Jan; Katayama, Toshiaki; Bonnal, Raoul J P; Yoshiura, Koh-ichiro

    2012-09-21

    The University of California, Santa Cruz (UCSC) genome database is among the most used sources of genomic annotation in human and other organisms. The database offers an excellent web-based graphical user interface (the UCSC genome browser) and several means for programmatic queries. A simple application programming interface (API) in a scripting language aimed at the biologist was however not yet available. Here, we present the Ruby UCSC API, a library to access the UCSC genome database using Ruby. The API is designed as a BioRuby plug-in and built on the ActiveRecord 3 framework for the object-relational mapping, making writing SQL statements unnecessary. The current version of the API supports databases of all organisms in the UCSC genome database including human, mammals, vertebrates, deuterostomes, insects, nematodes, and yeast.The API uses the bin index-if available-when querying for genomic intervals. The API also supports genomic sequence queries using locally downloaded *.2bit files that are not stored in the official MySQL database. The API is implemented in pure Ruby and is therefore available in different environments and with different Ruby interpreters (including JRuby). Assisted by the straightforward object-oriented design of Ruby and ActiveRecord, the Ruby UCSC API will facilitate biologists to query the UCSC genome database programmatically. The API is available through the RubyGem system. Source code and documentation are available at https://github.com/misshie/bioruby-ucsc-api/ under the Ruby license. Feedback and help is provided via the website at http://rubyucscapi.userecho.com/.

  15. The Ruby UCSC API: accessing the UCSC genome database using Ruby

    Science.gov (United States)

    2012-01-01

    Background The University of California, Santa Cruz (UCSC) genome database is among the most used sources of genomic annotation in human and other organisms. The database offers an excellent web-based graphical user interface (the UCSC genome browser) and several means for programmatic queries. A simple application programming interface (API) in a scripting language aimed at the biologist was however not yet available. Here, we present the Ruby UCSC API, a library to access the UCSC genome database using Ruby. Results The API is designed as a BioRuby plug-in and built on the ActiveRecord 3 framework for the object-relational mapping, making writing SQL statements unnecessary. The current version of the API supports databases of all organisms in the UCSC genome database including human, mammals, vertebrates, deuterostomes, insects, nematodes, and yeast. The API uses the bin index—if available—when querying for genomic intervals. The API also supports genomic sequence queries using locally downloaded *.2bit files that are not stored in the official MySQL database. The API is implemented in pure Ruby and is therefore available in different environments and with different Ruby interpreters (including JRuby). Conclusions Assisted by the straightforward object-oriented design of Ruby and ActiveRecord, the Ruby UCSC API will facilitate biologists to query the UCSC genome database programmatically. The API is available through the RubyGem system. Source code and documentation are available at https://github.com/misshie/bioruby-ucsc-api/ under the Ruby license. Feedback and help is provided via the website at http://rubyucscapi.userecho.com/. PMID:22994508

  16. An R2RML Mapping Management API in Java : Making an API Independent of its Dependencies

    OpenAIRE

    Strandhaug, Marius

    2014-01-01

    When developing an Application Programming Interface (API), there is often a need to use other libraries to implement some of the functionality. However, using an external library will make the API dependent on it. There may be several libraries that implement the needed functionality. A problem arises if the user needs to use a different library than what the API supports. The user should be able to choose which underlying library the API will use. To achieve this, the API will have to be ma...

  17. Gigabits to the Desktop: Installing tomorrow`s networks today

    Energy Technology Data Exchange (ETDEWEB)

    Kuhfuss, T.C.; Phillips, P.T.

    1994-03-01

    Argonne is one of the US Department of Energy`s world class research institutions. Leading edge computing tools and networks allow Argonne to maintain and enhance this reputation. One current effort to deploy leading edge tools is the Argonne ``Gigabits to the Desktop`` project. While the delivering and using gigabits to the desktop is little more than a hope at this time, this paper will discuss the hurdles to achieving it and how to tear down as many hurdles as possible. Under this project, four distinct areas are being investigated and enhanced. This paper will discuss briefly the applications and tools that we see driving the requirement for gigabits to the desktop. It will touch on a functional description of our``ideal`` workstations, architectures and the candidates for the next generation network capable of delivering gigabits. Lastly, it will provide an in-depth analysis of physical layer options and attempt to prove that this area, while the least risky, must be done properly, with the proper media. This paper assumes one important point. It assumes that bandwidth is essentially free. We will discuss network architectures and physical installation recommendations which have a fixed cost. However on a campus, there is no marginal cost for additional packets on these networks once the network infrastructure is installed. This point is important when extrapolating our conclusions to the wide area. The marginal cost of a packet sent to a commercial network is usually non zero. This fact may prove to be a great hindrance in migrating the applications mentioned beyond the organizational boundaries.

  18. The Proteins API: accessing key integrated protein and genome information.

    Science.gov (United States)

    Nightingale, Andrew; Antunes, Ricardo; Alpi, Emanuele; Bursteinas, Borisas; Gonzales, Leonardo; Liu, Wudong; Luo, Jie; Qi, Guoying; Turner, Edd; Martin, Maria

    2017-07-03

    The Proteins API provides searching and programmatic access to protein and associated genomics data such as curated protein sequence positional annotations from UniProtKB, as well as mapped variation and proteomics data from large scale data sources (LSS). Using the coordinates service, researchers are able to retrieve the genomic sequence coordinates for proteins in UniProtKB. This, the LSS genomics and proteomics data for UniProt proteins is programmatically only available through this service. A Swagger UI has been implemented to provide documentation, an interface for users, with little or no programming experience, to 'talk' to the services to quickly and easily formulate queries with the services and obtain dynamically generated source code for popular programming languages, such as Java, Perl, Python and Ruby. Search results are returned as standard JSON, XML or GFF data objects. The Proteins API is a scalable, reliable, fast, easy to use RESTful services that provides a broad protein information resource for users to ask questions based upon their field of expertise and allowing them to gain an integrated overview of protein annotations available to aid their knowledge gain on proteins in biological processes. The Proteins API is available at (http://www.ebi.ac.uk/proteins/api/doc). © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  19. The MPO API: A tool for recording scientific workflows

    International Nuclear Information System (INIS)

    Wright, John C.; Greenwald, Martin; Stillerman, Joshua; Abla, Gheni; Chanthavong, Bobby; Flanagan, Sean; Schissel, David; Lee, Xia; Romosan, Alex; Shoshani, Arie

    2014-01-01

    Highlights: • A description of a new framework and tool for recording scientific workflows, especially those resulting from simulation and analysis. • An explanation of the underlying technologies used to implement this web based tool. • Several examples of using the tool. - Abstract: Data from large-scale experiments and extreme-scale computing is expensive to produce and may be used for high-consequence applications. The Metadata, Provenance and Ontology (MPO) project builds on previous work [M. Greenwald, Fusion Eng. Des. 87 (2012) 2205–2208] and is focused on providing documentation of workflows, data provenance and the ability to data-mine large sets of results. While there are important design and development aspects to the data structures and user interfaces, we concern ourselves in this paper with the application programming interface (API) – the set of functions that interface with the data server. Our approach for the data server is to follow the Representational State Transfer (RESTful) software architecture style for client–server communication. At its core, the API uses the POST and GET methods of the HTTP protocol to transfer workflow information in message bodies to targets specified in the URL to and from the database via a web server. Higher level API calls are built upon this core API. This design facilitates implementation on different platforms and in different languages and is robust to changes in the underlying technologies used. The command line client implementation can communicate with the data server from any machine with HTTP access

  20. The Proteins API: accessing key integrated protein and genome information

    Science.gov (United States)

    Antunes, Ricardo; Alpi, Emanuele; Gonzales, Leonardo; Liu, Wudong; Luo, Jie; Qi, Guoying; Turner, Edd

    2017-01-01

    Abstract The Proteins API provides searching and programmatic access to protein and associated genomics data such as curated protein sequence positional annotations from UniProtKB, as well as mapped variation and proteomics data from large scale data sources (LSS). Using the coordinates service, researchers are able to retrieve the genomic sequence coordinates for proteins in UniProtKB. This, the LSS genomics and proteomics data for UniProt proteins is programmatically only available through this service. A Swagger UI has been implemented to provide documentation, an interface for users, with little or no programming experience, to ‘talk’ to the services to quickly and easily formulate queries with the services and obtain dynamically generated source code for popular programming languages, such as Java, Perl, Python and Ruby. Search results are returned as standard JSON, XML or GFF data objects. The Proteins API is a scalable, reliable, fast, easy to use RESTful services that provides a broad protein information resource for users to ask questions based upon their field of expertise and allowing them to gain an integrated overview of protein annotations available to aid their knowledge gain on proteins in biological processes. The Proteins API is available at (http://www.ebi.ac.uk/proteins/api/doc). PMID:28383659

  1. Desktop computer graphics for RMS/payload handling flight design

    Science.gov (United States)

    Homan, D. J.

    1984-01-01

    A computer program, the Multi-Adaptive Drawings, Renderings and Similitudes (MADRAS) program, is discussed. The modeling program, written for a desktop computer system (the Hewlett-Packard 9845/C), is written in BASIC and uses modular construction of objects while generating both wire-frame and hidden-line drawings from any viewpoint. The dimensions and placement of objects are user definable. Once the hidden-line calculations are made for a particular viewpoint, the viewpoint may be rotated in pan, tilt, and roll without further hidden-line calculations. The use and results of this program are discussed.

  2. Evaluation of usefulness and availability for orthopedic surgery using clavicle fracture model manufactured by desktop 3D printer

    International Nuclear Information System (INIS)

    Oh, Wang Kyun

    2014-01-01

    Usefulness and clinical availability for surgery efficiency were evaluated by conducting pre-operative planning with a model manufactured by desktop 3D printer by using clavicle CT image. The patient-customized clavicle fracture model was manufactured by desktop 3D printer of FDM wire laminated processing method by converting the CT image into STL file in Open Source DICOM Viewer Osirix. Also, the model of the original shape before damaged was restored and manufactured by Mirror technique based on STL file of not fractured clavicle of the other side by using the symmetry feature of the human body. For the model, the position and size, degree of the fracture was equally printed out. Using the clavicle model directly manufactured with low cost and less time in Department of Radiology is considered to be useful because it can reduce secondary damage during surgery and increase surgery efficiency with Minimal invasive percutaneous plate osteosynthesis(MIPO)

  3. Evaluation of usefulness and availability for orthopedic surgery using clavicle fracture model manufactured by desktop 3D printer

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Wang Kyun [Dept. of Diagnostic Radiology, Cheongju Medical Center, Cheongju (Korea, Republic of)

    2014-09-15

    Usefulness and clinical availability for surgery efficiency were evaluated by conducting pre-operative planning with a model manufactured by desktop 3D printer by using clavicle CT image. The patient-customized clavicle fracture model was manufactured by desktop 3D printer of FDM wire laminated processing method by converting the CT image into STL file in Open Source DICOM Viewer Osirix. Also, the model of the original shape before damaged was restored and manufactured by Mirror technique based on STL file of not fractured clavicle of the other side by using the symmetry feature of the human body. For the model, the position and size, degree of the fracture was equally printed out. Using the clavicle model directly manufactured with low cost and less time in Department of Radiology is considered to be useful because it can reduce secondary damage during surgery and increase surgery efficiency with Minimal invasive percutaneous plate osteosynthesis(MIPO)

  4. DySectAPI: Scalable Prescriptive Debugging

    DEFF Research Database (Denmark)

    Jensen, Nicklas Bo; Karlsson, Sven; Quarfot Nielsen, Niklas

    lightweight debugging models scale well, they can currently only debug a subset of bug classes. DySectAPI fills the gap between these two approaches with a novel user-guided approach. Using both experimental results and analytical modeling we show how DySectAPI scales and can run with a low overhead...

  5. Developing A Quantum Circuit Simulator API

    Science.gov (United States)

    Mihai Dorian, Stancu; Emil Marin, Popa

    2015-09-01

    In this paper we propose the design and implementation of a quantum circuit simulator API. Currently the API allows users to implement, debug and test the following two quantum algorithms: Bernstein-Vazirani's algorithm and Simon's Algorithm. The goal is to create a framework that will allow quantum computer scientists to easily develop new quantum algorithms.

  6. Validation of the Parlay API through prototyping

    NARCIS (Netherlands)

    Hellenthal, J.W.; Planken, F.J.M.; Wegdam, M.

    2001-01-01

    The desire within the telecommunications world for new and faster business growth has been a major drive towards the development of open network API. Over the past 7 years several (semi) standardization groups have announced work on network API, including TINA-C, JAIN, IEEE P1520, INforum, 3GPP,

  7. Aggressiveness index of Apis Mellifera (Hymenoptera: Aapidae

    Directory of Open Access Journals (Sweden)

    Jennyfer Insuasty Torres

    2004-01-01

    Full Text Available An index measuring the aggressiveness among ten colonies of Apis mellifera was elaborated based on the third generation synthetic indices by Charum et al. (1999. The index values are subject to a fixed parameter used as the beginning or standard value, and correspond to the aggressive features of some Africans colonies studied by Rothenbuler et al. (1968. In the ten colonies the index values are notably smaller than those of African colonies and are biased to the lowest values. This indicates, that neither of the colonies presents an extreme aggressive behavior and it is possible that they have not Africans genotypes. These results are an indirect proof of the index. Nevertheless, it could be improved by the introduction of other factors such as, climate and colony management.

  8. Meeting the multiscale challenge: representing physiology processes over ApiNATOMY circuits using bond graphs.

    Science.gov (United States)

    de Bono, B; Safaei, S; Grenon, P; Hunter, P

    2018-02-06

    We introduce, and provide examples of, the application of the bond graph formalism to explicitly represent biophysical processes between and within modular biological compartments in ApiNATOMY. In particular, we focus on modelling scenarios from acid-base physiology to link distinct process modalities as bond graphs over an ApiNATOMY circuit of multiscale compartments. The embedding of bond graphs onto ApiNATOMY compartments provides a semantically and mathematically explicit basis for the coherent representation, integration and visualisation of multiscale physiology processes together with the compartmental topology of those biological structures that convey these processes.

  9. XMPP API pro webové aplikace

    OpenAIRE

    Vaisar, Tomáš

    2011-01-01

    Tato práce se zabývá návrhem a implementací API umožňující tvorbu XMPP aplikací v ECMAScriptu. Její součástí je implementace navrženého API formou ukázkového pluginu pro XMPP klienta Jabbim. Součástí práce je též implementace hry Dáma vytvořená v ECMAScriptu s využitím navrženého API. Na závěr jsou představena možná rozšíření API v budoucnosti. This thesis deals with design and implementation of an API, that allows creating XMPP applications using ECMAScript. Thesis includes implementation...

  10. Investigation into process-induced de-aggregation of cohesive micronised API particles.

    Science.gov (United States)

    Hoffmann, Magnus; Wray, Patrick S; Gamble, John F; Tobyn, Mike

    2015-09-30

    The aim of this study was to assess the impact of unit processes on the de-aggregation of a cohesive micronised API within a pharmaceutical formulation using near-infrared chemical imaging. The impact on the primary API particles was also investigated using an image-based particle characterization system with integrated Raman analysis. The blended material was shown to contain large, API rich domains which were distributed in-homogeneously across the sample, suggesting that the blending process was not aggressive enough to disperse aggregates of micronised drug particles. Cone milling, routinely used to improve the homogeneity of such cohesive formulations, was observed to substantially reduce the number and size of API rich domains; however, several smaller API domains survived the milling process. Conveyance of the cone milled formulation through the Alexanderwerk WP120 powder feed system completely dispersed all remaining aggregates. Importantly, powder feed transmission of the un-milled formulation was observed to produce an equally homogeneous API distribution. The size of the micronised primary drug particles remained unchanged during powder feed transmission. These findings provide further evidence that this powder feed system does induce shear, and is in fact better able to disperse aggregates of a cohesive micronised API within a blend than the blend-mill-blend step. Crown Copyright © 2015. Published by Elsevier B.V. All rights reserved.

  11. Apoptosis inhibitor 5 (API-5; AAC-11; FIF) is upregulated in human carcinomas in vivo.

    Science.gov (United States)

    Koci, Lenka; Chlebova, Katarina; Hyzdalova, Martina; Hofmanova, Jirina; Jira, Miroslav; Kysela, Petr; Kozubik, Alois; Kala, Zdenek; Krejci, Pavel

    2012-04-01

    Apoptosis inhibitor 5 (API-5) is a 55 kDa nuclear protein with potent anti-apoptotic signaling in tumor cells in vitro. In this study, we analyzed the expression of the API-5 protein in vivo in a broad spectrum of human carcinomas, including those of the colon, lung, liver, kidney, pancreas, stomach and esophagus using tumor tissues obtained during tumor resection. The results showed significant upregulation of API-5 expression in biopsies of lung (23%, n=13) and colorectal tumors (33%, n=27) in comparison with biopsies from the adjacent normal tissue. Colon cancer biopsies were used to study the cell populations with an upregulated level of expression of API-5 more closely. Using a magnetic bead-based selection for the epithelial cell marker EpCAM, we purified epithelial cells from the tumor and control tissues and analyzed these cells for API-5 expression by western immunoblotting. We observed that EpCAM-positive tumor cells expressed API-5 in all three colorectal cancer cases tested, in contrast to the control EpCAM-positive and EpCAM-negative cells isolated from the control or tumor tissues. These data suggest that the expression of the API-5 protein is upregulated in tumor epithelial cells and may serve as a prognostic marker in colorectal cancer.

  12. Identification of Complete Repertoire of Apis florea Odorant Receptors Reveals Complex Orthologous Relationships with Apis mellifera

    Science.gov (United States)

    Karpe, Snehal D.; Jain, Rikesh; Brockmann, Axel; Sowdhamini, Ramanathan

    2016-01-01

    Abstract We developed a computational pipeline for homology based identification of the complete repertoire of olfactory receptor (OR) genes in the Asian honey bee species, Apis florea. Apis florea is phylogenetically the most basal honey bee species and also the most distant sister species to the Western honey bee Apis mellifera, for which all OR genes had been identified before. Using our pipeline, we identified 180 OR genes in A. florea, which is very similar to the number of ORs identified in A. mellifera (177 ORs). Many characteristics of the ORs including gene structure, synteny of tandemly repeated ORs and basic phylogenetic clustering are highly conserved. The composite phylogenetic tree of A. florea and A. mellifera ORs could be divided into 21 clades which are in harmony with the existing Hymenopteran tree. However, we found a few nonorthologous OR relationships between both species as well as independent pseudogenization of ORs suggesting separate evolutionary changes. Particularly, a subgroup of the OR gene clade XI, which had been hypothesized to code cuticular hydrocarbon receptors showed a high number of species-specific ORs. RNAseq analysis detected a total number of 145 OR transcripts in male and 162 in female antennae. Most of the OR genes were highly expressed on the female antennae. However, we detected five distinct male-biased OR genes, out of which three genes (AfOr11, AfOr18, AfOr170P) were shown to be male-biased in A. mellifera, too, thus corroborating a behavioral function in sex-pheromone communication. PMID:27540087

  13. MICA: desktop software for comprehensive searching of DNA databases

    Directory of Open Access Journals (Sweden)

    Glick Benjamin S

    2006-10-01

    Full Text Available Abstract Background Molecular biologists work with DNA databases that often include entire genomes. A common requirement is to search a DNA database to find exact matches for a nondegenerate or partially degenerate query. The software programs available for such purposes are normally designed to run on remote servers, but an appealing alternative is to work with DNA databases stored on local computers. We describe a desktop software program termed MICA (K-Mer Indexing with Compact Arrays that allows large DNA databases to be searched efficiently using very little memory. Results MICA rapidly indexes a DNA database. On a Macintosh G5 computer, the complete human genome could be indexed in about 5 minutes. The indexing algorithm recognizes all 15 characters of the DNA alphabet and fully captures the information in any DNA sequence, yet for a typical sequence of length L, the index occupies only about 2L bytes. The index can be searched to return a complete list of exact matches for a nondegenerate or partially degenerate query of any length. A typical search of a long DNA sequence involves reading only a small fraction of the index into memory. As a result, searches are fast even when the available RAM is limited. Conclusion MICA is suitable as a search engine for desktop DNA analysis software.

  14. Desktop-VR system for preflight 3D navigation training

    Science.gov (United States)

    Aoki, Hirofumi; Oman, Charles M.; Buckland, Daniel A.; Natapoff, Alan

    Crews who inhabit spacecraft with complex 3D architecture frequently report inflight disorientation and navigation problems. Preflight virtual reality (VR) training may reduce those risks. Although immersive VR techniques may better support spatial orientation training in a local environment, a non-immersive desktop (DT) system may be more convenient for navigation training in "building scale" spaces, especially if the two methods achieve comparable results. In this study trainees' orientation and navigation performance during simulated space station emergency egress tasks was compared while using immersive head-mounted display (HMD) and DT-VR systems. Analyses showed no differences in pointing angular-error or egress time among the groups. The HMD group was significantly faster than DT group when pointing from destination to start location and from start toward different destination. However, this may be attributed to differences in the input device used (a head-tracker for HMD group vs. a keyboard touchpad or a gamepad in the DT group). All other 3D navigation performance measures were similar using the immersive and non-immersive VR systems, suggesting that the simpler desktop VR system may be useful for astronaut 3D navigation training.

  15. 3d visualization of atomistic simulations on every desktop

    International Nuclear Information System (INIS)

    Peled, Dan; Silverman, Amihai; Adler, Joan

    2013-01-01

    Once upon a time, after making simulations, one had to go to a visualization center with fancy SGI machines to run a GL visualization and make a movie. More recently, OpenGL and its mesa clone have let us create 3D on simple desktops (or laptops), whether or not a Z-buffer card is present. Today, 3D a la Avatar is a commodity technique, presented in cinemas and sold for home TV. However, only a few special research centers have systems large enough for entire classes to view 3D, or special immersive facilities like visualization CAVEs or walls, and not everyone finds 3D immersion easy to view. For maximum physics with minimum effort a 3D system must come to each researcher and student. So how do we create 3D visualization cheaply on every desktop for atomistic simulations? After several months of attempts to select commodity equipment for a whole room system, we selected an approach that goes back a long time, even predating GL. The old concept of anaglyphic stereo relies on two images, slightly displaced, and viewed through colored glasses, or two squares of cellophane from a regular screen/projector or poster. We have added this capability to our AViz atomistic visualization code in its new, 6.1 version, which is RedHat, CentOS and Ubuntu compatible. Examples using data from our own research and that of other groups will be given

  16. SERVICE HANDBOOK FOR THE DESKTOP SUPPORT CONTRACT WIH IT DIVISION

    CERN Document Server

    2000-01-01

    A Desktop Support Contract has been running since January 1999 to offer help to all users at CERN with problems that occur with their desktop computers. The contract is run conjointly by the Swedish Company WM-data and the Swiss company DCS.The contract is comprised of the Computing Helpdesk, a General Service for all parts of CERN and also Local Service for those divisions and groups that want faster response times and additional help with their specific computer environment.In order to describe what services are being offered, and also to give a better understanding of the structure of the contract, a Service Handbook has been created. The intended audience for the Service Handbook is everyone that is using the contract, i.e. users, managers and also the service staff inside the contract. In the handbook you will find what help you can get from the contract, how to get in touch with the contract, and also what response times you can expect. Since the computer environment at CERN is a never-changing entity, ...

  17. Design and validation of a 3D virtual reality desktop system for sonographic length and volume measurements in early pregnancy evaluation.

    Science.gov (United States)

    Baken, Leonie; van Gruting, Isabelle M A; Steegers, Eric A P; van der Spek, Peter J; Exalto, Niek; Koning, Anton H J

    2015-03-01

    To design and validate a desktop virtual reality (VR) system, for presentation and assessment of volumetric data, based on commercially off-the-shelf hardware as an alternative to a fully immersive CAVE-like I-Space VR system. We designed a desktop VR system, using a three-dimensional (3D) monitor and a six degrees-of-freedom tracking system. A personal computer uses the V-Scope (Erasmus MC, Rotterdam, The Netherlands) volume-rendering application, developed for the I-Space, to create a hologram of volumetric data. Inter- and intraobserver reliability for crown-rump length and embryonic volume measurements are investigated using Bland-Altman plots and intraclass correlation coefficients. Time required for the measurements was recorded. Comparing the I-Space and the desktop VR system, the mean difference for crown-rump length is -0.34% (limits of agreement -2.58-1.89, ±2.24%) and for embryonic volume -0.92% (limits of agreement -6.97-5.13, ±6.05%). Intra- and interobserver intraclass correlation coefficients of the desktop VR system were all >0.99. Measurement times were longer on the desktop VR system compared with the I-Space, but the differences were not statistically significant. A user-friendly desktop VR system can be put together using commercially off-the-shelf hardware at an acceptable price. This system provides a valid and reliable method for embryonic length and volume measurements and can be used in clinical practice. © 2014 Wiley Periodicals, Inc.

  18. Taxonomic characterization of honey bee (Apis mellifera) pollen foraging based on non-overlapping paired-end sequencing of nuclear ribosomal loci

    Science.gov (United States)

    Cornman, Robert S.; Otto, Clint R.; Iwanowicz, Deborah; Pettis, Jeffery S

    2015-01-01

    Identifying plant taxa that honey bees (Apis mellifera) forage upon is of great apicultural interest, but traditional methods are labor intensive and may lack resolution. Here we evaluate a high-throughput genetic barcoding approach to characterize trap-collected pollen from multiple North Dakota apiaries across multiple years. We used the Illumina MiSeq platform to generate sequence scaffolds from non-overlapping 300-bp paired-end sequencing reads of the ribosomal internal transcribed spacers (ITS). Full-length sequence scaffolds represented ~530 bp of ITS sequence after adapter trimming, drawn from the 5’ of ITS1 and the 3’ of ITS2, while skipping the uninformative 5.8S region. Operational taxonomic units (OTUs) were picked from scaffolds clustered at 97% identity, searched by BLAST against the nt database, and given taxonomic assignments using the paired-read lowest common ancestor approach. Taxonomic assignments and quantitative patterns were consistent with known plant distributions, phenology, and observational reports of pollen foraging, but revealed an unexpected contribution from non-crop graminoids and wetland plants. The mean number of plant species assignments per sample was 23.0 (+/- 5.5) and the mean species diversity (effective number of equally abundant species) was 3.3 (+/- 1.2). Bray-Curtis similarities showed good agreement among samples from the same apiary and sampling date. Rarefaction plots indicated that fewer than 50,000 reads are typically needed to characterize pollen samples of this complexity. Our results show that a pre-compiled, curated reference database is not essential for genus-level assignments, but species-level assignments are hindered by database gaps, reference length variation, and probable errors in the taxonomic assignment, requiring post-hoc evaluation. Although the effective per-sample yield achieved using custom MiSeq amplicon primers was less than the machine maximum, primarily due to lower “read2” quality

  19. Web API Growing Pains : Loosely Coupled yet Strongly Tied

    NARCIS (Netherlands)

    Espinha, T.; Zaidman, A.; Gross, H.G.

    2014-01-01

    Web APIs provide a systematic and extensible approach for application-toapplication interaction. Developers using web APIs are forced to accompany the API providers in their software evolution tasks. In order to understand the distress caused by this imposition on web API client developers we

  20. Novel diagnostic tools for Asian (Apis cerana) and European (Apis mellifera) honey authentication.

    Science.gov (United States)

    Soares, Sónia; Grazina, Liliana; Mafra, Isabel; Costa, Joana; Pinto, M Alice; Duc, Hanh Pham; Oliveira, M Beatriz P P; Amaral, Joana S

    2018-03-01

    Honey can be produced by different species of honeybees, with two being of economic importance due to their use in apiculture, namely Apis mellifera (known as European honeybee) and Apis cerana (known as Asian honeybee). Due to the decline of the wild populations of the Asian honeybee, this honey generally attains much higher market value, being prone to adulteration. This work aims at proposing new tools, based on the use of molecular markers, for the entomological authentication of honey. To this end, new species-specific primers were designed targeting the tRNA leu -cox2 intergenic region and allowing the detection of A. cerana DNA by qualitative polymerase chain reaction (PCR). Additionally, a novel real-time PCR method with high resolution melting analysis was developed to target the 16S rRNA gene of both bee species, allowing their discrimination in different clusters. The proposed methodologies were further applied with success in the authentication of Asian and European honey samples by the identification of honeybee DNA, demonstrating the usefulness of these simple and cost-effective new approaches. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. DySectAPI: Scalable Prescriptive Debugging

    DEFF Research Database (Denmark)

    Jensen, Nicklas Bo; Karlsson, Sven; Quarfot Nielsen, Niklas

    We present the DySectAPI, a tool that allow users to construct probe trees for automatic, event-driven debugging at scale. The traditional, interactive debugging model, whereby users manually step through and inspect their application, does not scale well even for current supercomputers. While...... lightweight debugging models scale well, they can currently only debug a subset of bug classes. DySectAPI fills the gap between these two approaches with a novel user-guided approach. Using both experimental results and analytical modeling we show how DySectAPI scales and can run with a low overhead...

  2. Transcriptome differences in the hypopharyngeal gland between Western Honeybees (Apis mellifera) and Eastern Honeybees (Apis cerana).

    Science.gov (United States)

    Liu, Hao; Wang, Zi-Long; Tian, Liu-Qing; Qin, Qiu-Hong; Wu, Xiao-Bo; Yan, Wei-Yu; Zeng, Zhi-Jiang

    2014-08-30

    Apis mellifera and Apis cerana are two sibling species of Apidae. Apis cerana is adept at collecting sporadic nectar in mountain and forest region and exhibits stiffer hardiness and acarid resistance as a result of natural selection, whereas Apis mellifera has the advantage of producing royal jelly. To identify differentially expressed genes (DEGs) that affect the development of hypopharyngeal gland (HG) and/or the secretion of royal jelly between these two honeybee species, we performed a digital gene expression (DGE) analysis of the HGs of these two species at three developmental stages (newly emerged worker, nurse and forager). Twelve DGE-tag libraries were constructed and sequenced using the total RNA extracted from the HGs of newly emerged workers, nurses, and foragers of Apis mellifera and Apis cerana. Finally, a total of 1482 genes in Apis mellifera and 1313 in Apis cerana were found to exhibit an expression difference among the three developmental stages. A total of 1417 DEGs were identified between these two species. Of these, 623, 1072, and 462 genes showed an expression difference at the newly emerged worker, nurse, and forager stages, respectively. The nurse stage exhibited the highest number of DEGs between these two species and most of these were found to be up-regulated in Apis mellifera. These results suggest that the higher yield of royal jelly in Apis mellifera may be due to the higher expression level of these DEGs. In this study, we investigated the DEGs between the HGs of two sibling honeybee species (Apis mellifera and Apis cerana). Our results indicated that the gene expression difference was associated with the difference in the royal jelly yield between these two species. These results provide an important clue for clarifying the mechanisms underlying hypopharyngeal gland development and the production of royal jelly.

  3. Online referral and OPD booking from the GP desktop.

    Science.gov (United States)

    Nicholson, Caroline; Jackson, Claire L; Wright, Bernadette; Mainwaring, Paul; Holliday, Dimity; Lankowski, Andrew; Kardash, Christine

    2006-08-01

    The Brisbane Inner South E-referral Project (BISEP) developed an application which allowed general practitioners, from their desktop, to successfully search for and book an available hospital outpatient appointment for patients with suspected cancer, send the referral electronically, and inform the patient of both the appointment and referral during the consultation. The hospital changed their outpatient department processes to allow such functionality for local GPs with patients with suspected cancer, working from a mutually agreed set of best practice referral criteria. A group of 19 GPs participated in an 11-week pilot implementation of the application, and were enthusiastic about continuing and expanding the approach. Patient satisfaction measures post intervention indicated that they perceived no major disadvantage in this form of outpatient department referral.

  4. Desk-top microcomputer for lab-scale process control

    International Nuclear Information System (INIS)

    Overman, R.F.; Byrd, J.S.; Goosey, M.H.; Sand, R.J.

    1981-01-01

    A desk-top microcomputer was programmed to acquire the data from various process control sensors installed in a laboratory scale liquid-liquid extraction, pulse column facility. The parameters monitored included valve positions, gamma spectra, alpha radioactivity, temperature, pH, density, and flow rates. The program for the microcomputer is written in BASIC and requires about 31000 8-bit bytes of memory. All data is stored on floppy discs, and can be displayed or printed. Unexpected data values are brought to the process operator's attention via CRT display or print-out. The general organization of the program and a few subroutines unique to polling instruments are explained. Some of the data acquisition devices were designed and built at the Savannah River Laboratory. These include a pulse height analyzer, a data multiplexer, and a data acquisition instrument. A general description of the electronics design of these instruments is also given with emphasis placed on data formatting and bus addressing

  5. Direct Desktop Printed-Circuits-on-Paper Flexible Electronics

    Science.gov (United States)

    Zheng, Yi; He, Zhizhu; Gao, Yunxia; Liu, Jing

    2013-05-01

    There currently lacks of a way to directly write out electronics, just like printing pictures on paper by an office printer. Here we show a desktop printing of flexible circuits on paper via developing liquid metal ink and related working mechanisms. Through modifying adhesion of the ink, overcoming its high surface tension by dispensing machine and designing a brush like porous pinhead for printing alloy and identifying matched substrate materials among different papers, the slightly oxidized alloy ink was demonstrated to be flexibly printed on coated paper, which could compose various functional electronics and the concept of Printed-Circuits-on-Paper was thus presented. Further, RTV silicone rubber was adopted as isolating inks and packaging material to guarantee the functional stability of the circuit, which suggests an approach for printing 3D hybrid electro-mechanical device. The present work paved the way for a low cost and easygoing method in directly printing paper electronics.

  6. GRID : unlimited computing power on your desktop Conference MT17

    CERN Multimedia

    2001-01-01

    The Computational GRID is an analogy to the electrical power grid for computing resources. It decouples the provision of computing, data, and networking from its use, it allows large-scale pooling and sharing of resources distributed world-wide. Every computer, from a desktop to a mainframe or supercomputer, can provide computing power or data for the GRID. The final objective is to plug your computer into the wall and have direct access to huge computing resources immediately, just like plugging-in a lamp to get instant light. The GRID will facilitate world-wide scientific collaborations on an unprecedented scale. It will provide transparent access to major distributed resources of computer power, data, information, and collaborations.

  7. Assembly design semantic recognition using solid works-API

    OpenAIRE

    Hasan, Baha; Wikander, Jan; Onori, Mauro

    2016-01-01

    This paper describes a novel approach to recognize and model assembly semantic knowledge enclosed in product assembly features. The proposed approach is based on two stages: assembly semantic recognition and assembly semantic modelling. In the first stage, the internal boundary representation (B-rep) recognition method is utilized to extract assembly semantic knowledge from assembly CAD models using SolidWorks' API functions. In the second stage, a multi-level semantic assembly model is gener...

  8. Java Foundation Classes in a Nutshell Desktop Quick Reference

    CERN Document Server

    Flanagan, David

    1999-01-01

    Java Foundation Classes in a Nutshell is an indispensable quick reference for Java programmers who are writing applications that use graphics or graphical user interfaces. The author of the bestsellingJava in a Nutshell has written fast-paced introductions to the Java APIs that comprise the Java Foundation Classes (JFC), such as the Swing GUI components and Java 2D, so that you can start using these exciting new technologies right away. This book also includes O'Reilly's classic-style, quick-reference material for all of the classes in the javax.swing and java.awt packages and their numerous

  9. Detection of analyte binding to microarrays using gold nanoparticle labels and a desktop scanner

    DEFF Research Database (Denmark)

    Han, Anpan; Dufva, Martin; Belleville, Erik

    2003-01-01

    six attomoles of antibody-gold conjugates. This detection system was used in a competitive immunoassay to measure the concentration of the pesticide metabolite 2,6-dichlorobenzamide (BAM) in water samples. The results showed that the gold labeled antibodies functioned comparably with a fluorescent......Microarray hybridization or antibody binding can be detected by many techniques, however, only a few are suitable for widespread use since many of these detection techniques rely on bulky and expensive instruments. Here, we describe the usefulness of a simple and inexpensive detection method based...... on gold nanoparticle labeled antibodies visualized by a commercial, office desktop flatbed scanner. Scanning electron microscopy studies showed that the signal from the flatbed scanner was proportional to the surface density of the bound antibody-gold conjugates, and that the flatbed scanner could detect...

  10. FRAMEWORK PARA CONVERSÃO DE APLICATIVOS DELPHI DESKTOP EM APLICATIVOS ANDROID NATIVO

    Directory of Open Access Journals (Sweden)

    Rodrigo da Silva Riquena

    2014-08-01

    Full Text Available With the growing use of mobile devices by companies and organizations there is an increasing demand applications in production mobile platform. For certain companies, business success may depend on a mobile application which approaches the customers or improve the performance of internal processes. However, developing software for the mobile platform is an expensive process which takes time and resources. A framework to convert Delphi Desktop applications into native Android applications in an automatic way constitutes a useful tool for architects and software developers can contribute with the implementation phase of the application. Therefore, this work is based on methods and processes for software reengineering as the PRE / OO (Process of Reengineering Object Oriented, for automatic conversion of an application developed in Delphi environment in an application for Android mobile platform. At last, an experiment was performed with a real case to corroborate the goals.

  11. Desktop Modeling and Simulation: Parsimonious, yet Effective Discrete-Event Simulation Analysis

    Science.gov (United States)

    Bradley, James R.

    2012-01-01

    This paper evaluates how quickly students can be trained to construct useful discrete-event simulation models using Excel The typical supply chain used by many large national retailers is described, and an Excel-based simulation model is constructed of it The set of programming and simulation skills required for development of that model are then determined we conclude that six hours of training are required to teach the skills to MBA students . The simulation presented here contains all fundamental functionallty of a simulation model, and so our result holds for any discrete-event simulation model. We argue therefore that Industry workers with the same technical skill set as students having completed one year in an MBA program can be quickly trained to construct simulation models. This result gives credence to the efficacy of Desktop Modeling and Simulation whereby simulation analyses can be quickly developed, run, and analyzed with widely available software, namely Excel.

  12. The CosmicWatch Desktop Muon Detector: a self-contained, pocket sized particle detector

    Science.gov (United States)

    Axani, S. N.; Frankiewicz, K.; Conrad, J. M.

    2018-03-01

    The CosmicWatch Desktop Muon Detector is a self-contained, hand-held cosmic ray muon detector that is valuable for astro/particle physics research applications and outreach. The material cost of each detector is under 100 and it takes a novice student approximately four hours to build their first detector. The detectors are powered via a USB connection and the data can either be recorded directly to a computer or to a microSD card. Arduino- and Python-based software is provided to operate the detector and an online application to plot the data in real-time. In this paper, we describe the various design features, evaluate the performance, and illustrate the detectors capabilities by providing several example measurements.

  13. Qualitative research ethics on the spot: Not only on the desktop.

    Science.gov (United States)

    Øye, Christine; Sørensen, Nelli Øvre; Glasdam, Stinne

    2016-06-01

    The increase in medical ethical regulations and bureaucracy handled by institutional review boards and healthcare institutions puts the researchers using qualitative methods in a challenging position. Based on three different cases from three different research studies, the article explores and discusses research ethical dilemmas. First, and especially, the article addresses the challenges for gatekeepers who influence the informant's decisions to participate in research. Second, the article addresses the challenges in following research ethical guidelines related to informed consent and doing no harm. Third, the article argues for the importance of having research ethical guidelines and review boards to question and discuss the possible ethical dilemmas that occur in qualitative research. Research ethics must be understood in qualitative research as relational, situational, and emerging. That is, that focus on ethical issues and dilemmas has to be paid attention on the spot and not only at the desktop. © The Author(s) 2015.

  14. ChemSpell Web Service API

    Data.gov (United States)

    U.S. Department of Health & Human Services — The ChemSpell Web Service API provides chemical name spell checking and chemical name synonym look-up. ChemSpell contains more than 1.3 million chemical names...

  15. System for Award Management (SAM) API

    Data.gov (United States)

    General Services Administration — The SAM API is a RESTful method of retrieving public information about the businesses, organizations, or individuals (referred to as entities) within the SAM entity...

  16. Online maps with APIs and webservices

    CERN Document Server

    Peterson, Michael P

    2014-01-01

    With the Internet now the primary method of accessing maps, this volume examines developments in the world of online map delivery, focusing in particular on application programmer interfaces such as the Google Maps API, and their utility in thematic mapping.

  17. Real World Uses For Nagios APIs

    Science.gov (United States)

    Singh, Janice

    2014-01-01

    This presentation describes the Nagios 4 APIs and how the NASA Advanced Supercomputing at Ames Research Center is employing them to upgrade its graphical status display (the HUD) and explain why it's worth trying to use them yourselves.

  18. A new detrended semipartial cross-correlation analysis: Assessing the important meteorological factors affecting API

    International Nuclear Information System (INIS)

    Shen, Chen-Hua

    2015-01-01

    To analyze the unique contribution of meteorological factors to the air pollution index (API), a new method, the detrended semipartial cross-correlation analysis (DSPCCA), is proposed. Based on both a detrended cross-correlation analysis and a DFA-based multivariate-linear-regression (DMLR), this method is improved by including a semipartial correlation technique, which is used to indicate the unique contribution of an explanatory variable to multiple correlation coefficients. The advantages of this method in handling nonstationary time series are illustrated by numerical tests. To further demonstrate the utility of this method in environmental systems, new evidence of the primary contribution of meteorological factors to API is provided through DMLR. Results show that the most important meteorological factors affecting API are wind speed and diurnal temperature range, and the explanatory ability of meteorological factors to API gradually strengthens with increasing time scales. The results suggest that DSPCCA is a useful method for addressing environmental systems. - Highlights: • A detrended multiple linear regression is shown. • A detrended semipartial cross correlation analysis is proposed. • The important meteorological factors affecting API are assessed. • The explanatory ability of meteorological factors to API gradually strengthens with increasing time scales.

  19. Drag and Drop API v HTML5

    OpenAIRE

    BARABÁŠ, Vít

    2013-01-01

    The work (the bachelor´s thesis) deals with a new way of web application management via the "drag and drop" technique in the HTML5 programming language. The work is divided into two parts. The first part consists of DND API description in HTML5. The support analysis within common web browsers is included as a part of this description. The second, practical part of the thesis focuses on a concept and the following realisation of a photogallery using DND API.

  20. A Practical Python API for Querying AFLOWLIB

    OpenAIRE

    Rosenbrock, Conred W.

    2017-01-01

    Large databases such as aflowlib.org provide valuable data sources for discovering material trends through machine learning. Although a REST API and query language are available, there is a learning curve associated with the AFLUX language that acts as a barrier for new users. Additionally, the data is stored using non-standard serialization formats. Here we present a high-level API that allows immediate access to the aflowlib data using standard python operators and language features. It pro...

  1. “Wrapping” X3DOM around Web Audio API

    Directory of Open Access Journals (Sweden)

    Andreas Stamoulias

    2015-12-01

    Full Text Available Spatial sound has a conceptual role in the Web3D environments, due to highly realism scenes that can provide. Lately the efforts are concentrated on the extension of the X3D/ X3DOM through spatial sound attributes. This paper presents a novel method for the introduction of spatial sound components in the X3DOM framework, based on X3D specification and Web Audio API. The proposed method incorporates the introduction of enhanced sound nodes for X3DOM which are derived by the implementation of the X3D standard components, enriched with accessional features of Web Audio API. Moreover, several examples-scenarios developed for the evaluation of our approach. The implemented examples established the achievability of new registered nodes in X3DOM, for spatial sound characteristics in Web3D virtual worlds.

  2. Physicochemical characterisation and investigation of the bonding mechanisms of API-titanate nanotube composites as new drug carrier systems.

    Science.gov (United States)

    Sipos, Barbara; Pintye-Hódi, Klára; Kónya, Zoltán; Kelemen, András; Regdon, Géza; Sovány, Tamás

    2017-02-25

    Titanate nanotube (TNT) has recently been explored as a new carrier material for active pharmaceutical ingredients (API). The aim of the present work was to reveal the physicochemical properties of API-TNT composites, focusing on the interactions between the TNTs and the incorporated APIs. Drugs belonging to different Biopharmaceutical Classification System (BCS) classes were loaded into TNTs: diltiazem hydrochloride (BCS I.), diclofenac sodium (BCS II.), atenolol (BCS III.) and hydrochlorothiazide (BCS IV.). Experimental results demonstrated that it is feasible for spiral cross-sectioned titanate nanotubes to carry drugs and maintain their bioactivity. The structural properties of the composites were characterized by a range of analytical techniques, including FT-IR, DSC, TG-MS, etc. The interactions between APIs and TNTs were identified as electrostatic attractions, mainly dominated by hydrogen bonds. Based on the results, it can be stated that the strength of the association depends on the hydrogen donor strength of the API. The drug release of incorporated APIs was evaluated from compressed tablets and compared to that of pure APIs. Differences noticed in the dissolution profiles due to incorporation showed a correlation with the strength of interactions between the APIs and the TNTs observed in the above analytical studies. Copyright © 2016 Elsevier B.V. All rights reserved.

  3. The development, validity, and reliability of the Addiction Profile Index (API).

    Science.gov (United States)

    Ögel, Kültegin; Evren, Cüneyt; Karadağ, Figen; Gürol, Defne Tamar

    2012-01-01

    The objective of this study was to develop a practical questionnaire for multidimensional assessment of problems associated with alcohol and substance abuse that would also be useful for treatment planning. The Addiction Profile Index (API) is a self-report questionnaire consisting of 37 items and the following 5 subscales: characteristics of substance use; dependency diagnosis; the effects of subsance use on the user; craving; motivation to quit using substances. The study included 345 alcohol and/or substance abusers from 2 addiction treatment clinics and a prison addiction service. The validity of the questionnaire was assessed using the Michigan Alcoholism Screening Test (MAST), Readiness to Change Questionnaire (SOCRATES), Penn Alcohol Craving Scale (PACS), Drug Craving Scale (DCS), Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), and Addiction Severity Index (ASI). The Cronbach's alpha coefficient for the total API was 0.89 and for the subscales it ranged from 0.63 to 0.86. Item-total correlation coefficients ranged from 0.42 to 0.89. The Spearman Brown split-half method coefficient for the total API was 0.83. In all, 4 factors were obtained using explanatory factor analysis that represented 52.3% of the total variance. The API craving subscale was observed to be consistent with PACS and the API motivation subscale was consistent with SOCRATES. The API total score was strongly correlated with the mean MAST score, and the composite ASI medical status, substance use, legal status, and family social relations subscale scores. Based on ROC analyses, the area under curve was 0.90. With a total API cut-off score of 4, the scale's sensitivity and specificity 0.85 was 0.78, respectively. The findings show that the API is a valid and reliable questionnaire that can be used to measure the severity of different dimensions of substance dependency.

  4. A RESTful API for accessing microbial community data for MG-RAST.

    Science.gov (United States)

    Wilke, Andreas; Bischof, Jared; Harrison, Travis; Brettin, Tom; D'Souza, Mark; Gerlach, Wolfgang; Matthews, Hunter; Paczian, Tobias; Wilkening, Jared; Glass, Elizabeth M; Desai, Narayan; Meyer, Folker

    2015-01-01

    Metagenomic sequencing has produced significant amounts of data in recent years. For example, as of summer 2013, MG-RAST has been used to annotate over 110,000 data sets totaling over 43 Terabases. With metagenomic sequencing finding even wider adoption in the scientific community, the existing web-based analysis tools and infrastructure in MG-RAST provide limited capability for data retrieval and analysis, such as comparative analysis between multiple data sets. Moreover, although the system provides many analysis tools, it is not comprehensive. By opening MG-RAST up via a web services API (application programmers interface) we have greatly expanded access to MG-RAST data, as well as provided a mechanism for the use of third-party analysis tools with MG-RAST data. This RESTful API makes all data and data objects created by the MG-RAST pipeline accessible as JSON objects. As part of the DOE Systems Biology Knowledgebase project (KBase, http://kbase.us) we have implemented a web services API for MG-RAST. This API complements the existing MG-RAST web interface and constitutes the basis of KBase's microbial community capabilities. In addition, the API exposes a comprehensive collection of data to programmers. This API, which uses a RESTful (Representational State Transfer) implementation, is compatible with most programming environments and should be easy to use for end users and third parties. It provides comprehensive access to sequence data, quality control results, annotations, and many other data types. Where feasible, we have used standards to expose data and metadata. Code examples are provided in a number of languages both to show the versatility of the API and to provide a starting point for users. We present an API that exposes the data in MG-RAST for consumption by our users, greatly enhancing the utility of the MG-RAST service.

  5. A RESTful API for accessing microbial community data for MG-RAST.

    Directory of Open Access Journals (Sweden)

    Andreas Wilke

    2015-01-01

    Full Text Available Metagenomic sequencing has produced significant amounts of data in recent years. For example, as of summer 2013, MG-RAST has been used to annotate over 110,000 data sets totaling over 43 Terabases. With metagenomic sequencing finding even wider adoption in the scientific community, the existing web-based analysis tools and infrastructure in MG-RAST provide limited capability for data retrieval and analysis, such as comparative analysis between multiple data sets. Moreover, although the system provides many analysis tools, it is not comprehensive. By opening MG-RAST up via a web services API (application programmers interface we have greatly expanded access to MG-RAST data, as well as provided a mechanism for the use of third-party analysis tools with MG-RAST data. This RESTful API makes all data and data objects created by the MG-RAST pipeline accessible as JSON objects. As part of the DOE Systems Biology Knowledgebase project (KBase, http://kbase.us we have implemented a web services API for MG-RAST. This API complements the existing MG-RAST web interface and constitutes the basis of KBase's microbial community capabilities. In addition, the API exposes a comprehensive collection of data to programmers. This API, which uses a RESTful (Representational State Transfer implementation, is compatible with most programming environments and should be easy to use for end users and third parties. It provides comprehensive access to sequence data, quality control results, annotations, and many other data types. Where feasible, we have used standards to expose data and metadata. Code examples are provided in a number of languages both to show the versatility of the API and to provide a starting point for users. We present an API that exposes the data in MG-RAST for consumption by our users, greatly enhancing the utility of the MG-RAST service.

  6. Programmatic access to logical models in the Cell Collective modeling environment via a REST API.

    Science.gov (United States)

    Kowal, Bryan M; Schreier, Travis R; Dauer, Joseph T; Helikar, Tomáš

    2016-01-01

    Cell Collective (www.cellcollective.org) is a web-based interactive environment for constructing, simulating and analyzing logical models of biological systems. Herein, we present a Web service to access models, annotations, and simulation data in the Cell Collective platform through the Representational State Transfer (REST) Application Programming Interface (API). The REST API provides a convenient method for obtaining Cell Collective data through almost any programming language. To ensure easy processing of the retrieved data, the request output from the API is available in a standard JSON format. The Cell Collective REST API is freely available at http://thecellcollective.org/tccapi. All public models in Cell Collective are available through the REST API. For users interested in creating and accessing their own models through the REST API first need to create an account in Cell Collective (http://thecellcollective.org). thelikar2@unl.edu. Technical user documentation: https://goo.gl/U52GWo. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  7. APIs and Researchers: The Emperor's New Clothes?

    Directory of Open Access Journals (Sweden)

    Jennifer Edmond

    2015-02-01

    Full Text Available As part of the Europeana Cloud (eCloud project, Trinity College Dublin investigated best practice in the use of web services, such as APIs, for accessing large data sets from cultural heritage collections. This research looked into the provision and use of APIs, and moreover, whether or not more customised programmatic access to datasets is what researchers want or need. In order to understand whether current patterns of API usage reflect a skills gap on the part of researchers or a mismatch of tool to purpose, we looked not only at the creators and developer/users of APIs, but also at humanists already re-using big data; approaches in cultural heritage institutions and other research infrastructures to bring API use to non-technical audiences; and the kinds of training and other support services available or emerging within the data-intensive humanities research lifecycle. We conducted both desk research and a series of 11 interviews with figures working as researchers, developers or data providers, including figures from both the API development and the data usage communities. This research, conducted under the eCloud project and supported by the European Commission’s ICT Policy and Support Programme (Grant number 325091, was begun in March 2014 and is now in its concluding validation stage. The results of the research are not yet finalised, but the contribution is already emerging of this work to the debate about APIs being either the way forward for digital cultural heritage collections, or the Emperor’s New Clothes (or maybe a bit of both.

  8. The putative serine protease inhibitor Api m 6 from Apis mellifera venom: recombinant and structural evaluation.

    Science.gov (United States)

    Michel, Y; McIntyre, M; Ginglinger, H; Ollert, M; Cifuentes, L; Blank, S; Spillner, E

    2012-01-01

    Immunoglobulin (Ig) E-mediated reactions to honeybee venom can cause severe anaphylaxis, sometimes with fatal consequences. Detailed knowledge of the allergic potential of all venom components is necessary to ensure proper diagnosis and treatment of allergy and to gain a better understanding of the allergological mechanisms of insect venoms. Our objective was to undertake an immunochemical and structural evaluation of the putative low-molecular-weight serine protease inhibitor Api m 6, a component of honeybee venom. We recombinantly produced Api m 6 as a soluble protein in Escherichia coli and in Spodoptera frugiperda (Sf9) insect cells.We also assessed specific IgE reactivity of venom-sensitized patients with 2 prokaryotically produced Api m 6 variants using enzyme-linked immunosorbent assay. Moreover, we built a structural model ofApi m 6 and compared it with other protease inhibitor structures to gain insights into the function of Api m 6. In a population of 31 honeybee venom-allergic patients, 26% showed specific IgE reactivity with prokaryotically produced Api m 6, showing it to be a minor but relevant allergen. Molecular modeling of Api m 6 revealed a typical fold of canonical protease inhibitors, supporting the putative function of this venom allergen. Although Api m 6 has a highly variant surface charge, its epitope distribution appears to be similar to that of related proteins. Api m 6 is a honeybee venom component with IgE-sensitizing potential in a fraction of venom-allergic patients. Recombinant Api m 6 can help elucidate individual component-resolved reactivity profiles and increase our understanding of immune responses to low-molecular-weight allergens

  9. BDE-209 in the Australian Environment: Desktop review

    International Nuclear Information System (INIS)

    English, Karin; Toms, Leisa-Maree L.; Gallen, Christie; Mueller, Jochen F.

    2016-01-01

    The commercial polybrominated diphenyl ether (PBDE) flame retardant mixture c-decaBDE is now being considered for listing on the Stockholm Convention on Persistent Organic Pollutants. The aim of our study was to review the literature regarding the use and detection of BDE-209, a major component of c-decaBDE, in consumer products and provide a best estimate of goods that are likely to contain BDE-209 in Australia. This review is part of a larger study, which will include quantitative testing of items to assess for BDE-209. The findings of this desktop review will be used to determine which items should be prioritized for quantitative testing. We identified that electronics, particularly televisions, computers, small household appliances and power boards, were the items that were most likely to contain BDE-209 in Australia. Further testing of these items should include items of various ages. Several other items were identified as high priority for future testing, including transport vehicles, building materials and textiles in non-domestic settings. The findings from this study will aid in the development of appropriate policies, should listing of c-decaBDE on the Stockholm Convention and Australia’s ratification of that listing proceed.

  10. BDE-209 in the Australian Environment: Desktop review

    Energy Technology Data Exchange (ETDEWEB)

    English, Karin, E-mail: k.english@uq.edu.au [School of Medicine, The University of Queensland, Brisbane (Australia); Children’s Health and Environment Program, Child Health Research Centre, The University of Queensland, Brisbane (Australia); Queensland Children’s Medical Research Institute, Children’s Health Research Centre, Brisbane (Australia); Toms, Leisa-Maree L. [School of Public Health and Social Work, and Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane (Australia); Gallen, Christie; Mueller, Jochen F. [The University of Queensland, National Research Centre for Environmental Toxicology (Entox), Brisbane (Australia)

    2016-12-15

    The commercial polybrominated diphenyl ether (PBDE) flame retardant mixture c-decaBDE is now being considered for listing on the Stockholm Convention on Persistent Organic Pollutants. The aim of our study was to review the literature regarding the use and detection of BDE-209, a major component of c-decaBDE, in consumer products and provide a best estimate of goods that are likely to contain BDE-209 in Australia. This review is part of a larger study, which will include quantitative testing of items to assess for BDE-209. The findings of this desktop review will be used to determine which items should be prioritized for quantitative testing. We identified that electronics, particularly televisions, computers, small household appliances and power boards, were the items that were most likely to contain BDE-209 in Australia. Further testing of these items should include items of various ages. Several other items were identified as high priority for future testing, including transport vehicles, building materials and textiles in non-domestic settings. The findings from this study will aid in the development of appropriate policies, should listing of c-decaBDE on the Stockholm Convention and Australia’s ratification of that listing proceed.

  11. CALIBRATION, OPTIMIZATION, AND SENSITIVITY AND UNCERTAINTY ALGORITHMS APPLICATION PROGRAMMING INTERFACE (COSU-API)

    Science.gov (United States)

    The Application Programming Interface (API) for Uncertainty Analysis, Sensitivity Analysis, and Parameter Estimation (UA/SA/PE API) tool development, here fore referred to as the Calibration, Optimization, and Sensitivity and Uncertainty Algorithms API (COSU-API), was initially d...

  12. Advanced API security securing APIs with OAuth 2.0, OpenID Connect, JWS, and JWE

    CERN Document Server

    Siriwardena, Prabath

    2014-01-01

    Advanced API Security is a complete reference to the next wave of challenges in enterprise security--securing public and private APIs. API adoption in both consumer and enterprises has gone beyond predictions. It has become the 'coolest' way of exposing business functionalities to the outside world. Both your public and private APIs, need to be protected, monitored and managed. Security is not an afterthought, but API security has evolved a lot in last five years. The growth of standards, out there, has been exponential. That's where AdvancedAPI Security comes in--to wade through the weeds

  13. Nielsen PrimeLocation Web/Desktop: Assessing and GIS Mapping Market Area

    Data.gov (United States)

    Social Security Administration — Nielsen PrimeLocation Web and Desktop Software Licensed for Internal Use only: Pop-Facts Demographics Database, Geographic Mapping Data Layers, Geo-Coding locations.

  14. MODAPS Web Services API for LANCE-MODIS

    Data.gov (United States)

    National Aeronautics and Space Administration — MODAPS Web Services API for LANCE-MODIS. This Application Programming Interface (API) encompasses a library of functions that provides programmatic data access to...

  15. Automated Ply Inspection (API) for AFP, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The Automated Ply Inspection (API) system autonomously inspects layups created by high speed automated fiber placement (AFP) machines. API comprises a high accuracy...

  16. Unified Medical Language System Terminology Services (UTS) API

    Data.gov (United States)

    U.S. Department of Health & Human Services — The UTS API is intended for application developers to perform Web service calls and retrieve UMLS data within their own applications. The UTS API provides the...

  17. Redesign of a Grignard-Based Active Pharmaceutical Ingredient (API) Batch Synthesis to a Flow Process for the Preparation of Melitracen HCl

    DEFF Research Database (Denmark)

    Pedersen, Michael J.; Skovby, Tommy; Mealy, Michael J.

    2018-01-01

    A Grignard-based batch process, for the preparation of Melitracen HCl, has been redesigned to fit a continuous reactor system. The Grignard addition is carried out at room temperature, with subsequent hydrolysis of the magnesium alkoxide intermediate followed by dehydration of the resulting alcoh...

  18. Correcting satellite-based precipitation products through SMOS soil moisture data assimilation in two land-surface models of different complexity: API and SURFEX

    Science.gov (United States)

    Real-time rainfall accumulation estimates at the global scale is useful for many applications. However, the real-time versions of satellite-based rainfall products are known to contain errors relative to real rainfall observed in situ. Recent studies have demonstrated how information about rainfall ...

  19. Comparative virulence and competition between Nosema apis and Nosema ceranae in honey bees (Apis mellifera).

    Science.gov (United States)

    Milbrath, Meghan O; van Tran, Toan; Huang, Wei-Fong; Solter, Leellen F; Tarpy, David R; Lawrence, Frank; Huang, Zachary Y

    2015-02-01

    Honey bees (Apis mellifera) are infected by two species of microsporidia: Nosema apis and Nosemaceranae. Epidemiological evidence indicates that N. ceranae may be replacing N. apis globally in A. mellifera populations, suggesting a potential competitive advantage of N. ceranae. Mixed infections of the two species occur, and little is known about the interactions among the host and the two pathogens that have allowed N. ceranae to become dominant in most geographical areas. We demonstrated that mixed Nosema species infections negatively affected honey bee survival (median survival=15-17days) more than single species infections (median survival=21days and 20days for N. apis and N. ceranae, respectively), with median survival of control bees of 27days. We found similar rates of infection (percentage of bees with active infections after inoculation) for both species in mixed infections, with N. apis having a slightly higher rate (91% compared to 86% for N. ceranae). We observed slightly higher spore counts in bees infected with N. ceranae than in bees infected with N. apis in single microsporidia infections, especially at the midpoint of infection (day 10). Bees with mixed infections of both species had higher spore counts than bees with single infections, but spore counts in mixed infections were highly variable. We did not see a competitive advantage for N. ceranae in mixed infections; N. apis spore counts were either higher or counts were similar for both species and more N. apis spores were produced in 62% of bees inoculated with equal dosages of the two microsporidian species. N. ceranae does not, therefore, appear to have a strong within-host advantage for either infectivity or spore growth, suggesting that direct competition in these worker bee mid-guts is not responsible for its apparent replacement of N. apis. Copyright © 2014 Elsevier Inc. All rights reserved.

  20. Pro REST API development with nodejs

    CERN Document Server

    Doglio, Fernando

    2015-01-01

    Pro REST API Development with Node.js is your guide to managing and understanding the full capabilities of successful REST development. API design is a hot topic in the programming world, but not many resources exist for developers to really understand how you can leverage the advantages. This book will provide a brief background on REST and the tools it provides (well known and not so well known). Understand how there is more to REST than just JSON and URLs. You will then cover and compare the maintained modules currently available in the npm community, including Express, Restify, Vatican,

  1. Life cycle assessment study of a Chinese desktop personal computer

    International Nuclear Information System (INIS)

    Duan Huabo; Eugster, Martin; Hischier, Roland; Streicher-Porte, Martin; Li Jinhui

    2009-01-01

    Associated with the tremendous prosperity in world electronic information and telecommunication industry, there continues to be an increasing awareness of the environmental impacts related to the accelerating mass production, electricity use, and waste management of electronic and electric products (e-products). China's importance as both a consumer and supplier of e-products has grown at an unprecedented pace in recent decade. Hence, this paper aims to describe the application of life cycle assessment (LCA) to investigate the environmental performance of Chinese e-products from a global level. A desktop personal computer system has been selected to carry out a detailed and modular LCA which follows the ISO 14040 series. The LCA is constructed by SimaPro software version 7.0 and expressed with the Eco-indicator'99 life cycle impact assessment method. For a sensitivity analysis of the overall LCA results, the so-called CML method is used in order to estimate the influence of the choice of the assessment method on the result. Life cycle inventory information is complied by ecoinvent 1.3 databases, combined with literature and field investigations on the present Chinese situation. The established LCA study shows that that the manufacturing and the use of such devices are of the highest environmental importance. In the manufacturing of such devices, the integrated circuits (ICs) and the Liquid Crystal Display (LCD) are those parts contributing most to the impact. As no other aspects are taken into account during the use phase, the impact is due to the way how the electricity is produced. The final process steps - i.e. the end of life phase - lead to a clear environmental benefit if a formal and modern, up-to-date technical system is assumed, like here in this study

  2. A formal MIM specification and tools for the common exchange of MIM diagrams: an XML-Based format, an API, and a validation method.

    Science.gov (United States)

    Luna, Augustin; Karac, Evrim I; Sunshine, Margot; Chang, Lucas; Nussinov, Ruth; Aladjem, Mirit I; Kohn, Kurt W

    2011-05-17

    The Molecular Interaction Map (MIM) notation offers a standard set of symbols and rules on their usage for the depiction of cellular signaling network diagrams. Such diagrams are essential for disseminating biological information in a concise manner. A lack of software tools for the notation restricts wider usage of the notation. Development of software is facilitated by a more detailed specification regarding software requirements than has previously existed for the MIM notation. A formal implementation of the MIM notation was developed based on a core set of previously defined glyphs. This implementation provides a detailed specification of the properties of the elements of the MIM notation. Building upon this specification, a machine-readable format is provided as a standardized mechanism for the storage and exchange of MIM diagrams. This new format is accompanied by a Java-based application programming interface to help software developers to integrate MIM support into software projects. A validation mechanism is also provided to determine whether MIM datasets are in accordance with syntax rules provided by the new specification. The work presented here provides key foundational components to promote software development for the MIM notation. These components will speed up the development of interoperable tools supporting the MIM notation and will aid in the translation of data stored in MIM diagrams to other standardized formats. Several projects utilizing this implementation of the notation are outlined herein. The MIM specification is available as an additional file to this publication. Source code, libraries, documentation, and examples are available at http://discover.nci.nih.gov/mim.

  3. JEnsembl: a version-aware Java API to Ensembl data systems.

    Science.gov (United States)

    Paterson, Trevor; Law, Andy

    2012-11-01

    The Ensembl Project provides release-specific Perl APIs for efficient high-level programmatic access to data stored in various Ensembl database schema. Although Perl scripts are perfectly suited for processing large volumes of text-based data, Perl is not ideal for developing large-scale software applications nor embedding in graphical interfaces. The provision of a novel Java API would facilitate type-safe, modular, object-orientated development of new Bioinformatics tools with which to access, analyse and visualize Ensembl data. The JEnsembl API implementation provides basic data retrieval and manipulation functionality from the Core, Compara and Variation databases for all species in Ensembl and EnsemblGenomes and is a platform for the development of a richer API to Ensembl datasources. The JEnsembl architecture uses a text-based configuration module to provide evolving, versioned mappings from database schema to code objects. A single installation of the JEnsembl API can therefore simultaneously and transparently connect to current and previous database instances (such as those in the public archive) thus facilitating better analysis repeatability and allowing 'through time' comparative analyses to be performed. Project development, released code libraries, Maven repository and documentation are hosted at SourceForge (http://jensembl.sourceforge.net).

  4. Java Source Code Analysis for API Migration to Embedded Systems

    Energy Technology Data Exchange (ETDEWEB)

    Winter, Victor [Univ. of Nebraska, Omaha, NE (United States); McCoy, James A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Guerrero, Jonathan [Univ. of Nebraska, Omaha, NE (United States); Reinke, Carl Werner [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Perry, James Thomas [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-02-01

    Embedded systems form an integral part of our technological infrastructure and oftentimes play a complex and critical role within larger systems. From the perspective of reliability, security, and safety, strong arguments can be made favoring the use of Java over C in such systems. In part, this argument is based on the assumption that suitable subsets of Java’s APIs and extension libraries are available to embedded software developers. In practice, a number of Java-based embedded processors do not support the full features of the JVM. For such processors, source code migration is a mechanism by which key abstractions offered by APIs and extension libraries can made available to embedded software developers. The analysis required for Java source code-level library migration is based on the ability to correctly resolve element references to their corresponding element declarations. A key challenge in this setting is how to perform analysis for incomplete source-code bases (e.g., subsets of libraries) from which types and packages have been omitted. This article formalizes an approach that can be used to extend code bases targeted for migration in such a manner that the threats associated the analysis of incomplete code bases are eliminated.

  5. EVALUATION OF CORROSION IN WELD REGION AND BASE METAL OF API 5L X80 PIPE IN MEDIUM CONTAINING HYDROGEN SULPHIDE

    Directory of Open Access Journals (Sweden)

    Bruno Nagle Armendro

    2012-09-01

    Full Text Available The objective of this study is to compare the corrosion resistance of the base metal (MB and weld region (RCS of a X80 pipeline in three types of aqueous solution of acetic acid (CH3COOH 0,5% by weight: naturally aerated, non-aerated and non-aerated with H2S. Linear polarization is employed for it determinates Polarization Resistance (Rp which allows comparing the corrosion resistance of steel in different conditions. The results show that Rp practically does not change with the immersion time (until 8 hours, for both regions. The two regions have higher Rp in non-aerated aqueous solution, intermediate Rp in non-aerated with H2S and lower Rp in naturally aerated; this is due the effect of oxygen in cathodic reactions and shows that H2S can accelerate slightly the corrosion. The RCS has greater Rp than the MB for any aeration conditions. The presence of alloying elements in RCS justifies this behavior. The morphology of corrosion was examined under an optical microscope (MO and shows that uniform corrosion is predominant.

  6. Jllumina - A comprehensive Java-based API for statistical Illumina Infinium HumanMethylation450 and Infinium MethylationEPIC BeadChip data processing

    Directory of Open Access Journals (Sweden)

    Almeida Diogo

    2016-10-01

    Full Text Available Measuring differential methylation of the DNA is the nowadays most common approach to linking epigenetic modifications to diseases (called epigenome-wide association studies, EWAS. For its low cost, its efficiency and easy handling, the Illumina HumanMethylation450 BeadChip and its successor, the Infinium MethylationEPIC BeadChip, is the by far most popular techniques for conduction EWAS in large patient cohorts. Despite the popularity of this chip technology, raw data processing and statistical analysis of the array data remains far from trivial and still lacks dedicated software libraries enabling high quality and statistically sound downstream analyses. As of yet, only R-based solutions are freely available for low-level processing of the Illumina chip data. However, the lack of alternative libraries poses a hurdle for the development of new bioinformatic tools, in particular when it comes to web services or applications where run time and memory consumption matter, or EWAS data analysis is an integrative part of a bigger framework or data analysis pipeline. We have therefore developed and implemented Jllumina, an open-source Java library for raw data manipulation of Illumina Infinium HumanMethylation450 and Infinium MethylationEPIC BeadChip data, supporting the developer with Java functions covering reading and preprocessing the raw data, down to statistical assessment, permutation tests, and identification of differentially methylated loci. Jllumina is fully parallelizable and publicly available at http://dimmer.compbio.sdu.dk/download.html

  7. Eksplorasi Aktinomiset Sebagai Penghasil Antibiotika Dari Tanah Mangrove Sonneratia Caseolaris Di Tanjung Api Api

    OpenAIRE

    Fatiqin, Awalul

    2015-01-01

    Actinomycetes are soil organisms that have traits that are common to bacteria and fungi but also have quite different characteristics that limit into one group which is distinctly different. Study aimed to explore the mangrove actinomycetes from soil and tested the antibacterial potency. Soil samples taken from the mangrove land at Tanjung Api-api mangrove species Sonneratia caseolaris. Activity test antibacterial using a method modified disk a test bacterium Escherichia coli. Identification ...

  8. Foraging behaviour of Apis mellifera adansonii Latreille ...

    African Journals Online (AJOL)

    Foraging behaviour of Apis mellifera adansonii Latreille (Hymenoptera : Apidae) on Daniellia oliveri, Delonix regia, Hymenocardia acida and Terminalia mantaly flowers in Ngaoundéré (Cameroon). F-N Tchuenguem Fohouo, SF Tope, AP Mbianda, J Messi, D Bruckner ...

  9. API and ISO standards can be combined

    International Nuclear Information System (INIS)

    Weightman, R.T.; Warnack, M.F.

    1992-01-01

    This paper reports that oil field equipment and product manufacturers can maintain a competitive advantage and minimize costs by integrating American Petroleum Institute (API) licensing programs with International Standards Organization (ISO) 9001 standards under one quality system. A combined quality system approach can position a company for quality system certification under ISO 9001 while maintaining API specifications. Furthermore, only one quality system manual is needed for API licensing and ISO certification, avoiding duplication of effort. The benefits of a documented quality program include the flowing: Job descriptions and personnel qualification requirements are documented; The improved documentation allows direct tracing of specific production activities; Laboratory test methods and calibration of test equipment follow accepted standards for more reliable and reproducible test data; Quality control becomes proactive, not reactive, through internal process controls previously not implemented; Employee attitudes improve through appreciation for the overall goals of the company; Ambiguous quality issues, such as documenting special customer requirements, are easily resolved; and The company image improves with customers, particularly for those that require API Specification Q1 or ISO 9001 compliance or those having their own quality performance standards

  10. CHEMICAL COMPOSITION AND ANTIOXIDANT ACTIVITY OF APIS ...

    African Journals Online (AJOL)

    CHEMICAL COMPOSITION AND ANTIOXIDANT ACTIVITY OF APIS. MELLIFERA BEE POLLEN FROM NORTHWEST ALGERIA. A. Rebiai* and T.Lanez. University of El Oued, VTRS Laboratory, P.O. Box 789, 39000, El Oued, Algeria. Received: 08 November 2012 / Accepted: 23 December 2012 / Published online: 31 ...

  11. Standard methods for Apis mellifera propolis research

    Science.gov (United States)

    Propolis is one of the most fascinating honey bee (Apis mellifera L.) products. It is a plant derived product that bees produce from resins that they collect from different plant organs and with which they mix beeswax. Propolis is a building material and a protective agent in the beehive. It also pl...

  12. How Do Developers Use APIs? A Case Study in Concurrency

    DEFF Research Database (Denmark)

    Blom, Stefan; Kiniry, Joseph; Huisman, Marieke

    2013-01-01

    With the omnipresent usage of APIs in software development, it has become important to analyse how the routines and functionalities of APIs are actually used. This information is in particular useful for API developers, to make decisions about future updates of the API. However, also for developers...... of static analysis and verification tools this information is highly important, because it indicates where and how to put the most efficient effort in annotating APIs, to make them usable for the static analysis and verification tools. This paper presents an analysis of the usage of the routines...

  13. Identification of Candida dubliniensis Based on Temperature and Utilization of Xylose and α-Methyl-d-Glucoside as Determined with the API 20C AUX and Vitek YBC Systems

    Science.gov (United States)

    Gales, A. C.; Pfaller, M. A.; Houston, A. K.; Joly, S.; Sullivan, D. J.; Coleman, D. C.; Soll, D. R.

    1999-01-01

    To have a better understanding of the role of Candida dubliniensis in clinical infections, it is essential that microbiology laboratories can identify this species rapidly and accurately in clinical specimens. C. dubliniensis has been reported to lack the ability to utilize xylose (XYL) and α-methyl-d-glucoside (MDG) and to grow poorly or not at all at 45°C, whereas Candida albicans isolates utilize XYL and MDG and usually grow well at 45°C. We tested 66 isolates of C. dubliniensis and 100 isolates of C. albicans with both the API 20C AUX and Vitek YBC systems to evaluate the ability of the XYL and MDG tests contained within each of these systems to distinguish between the two species. The ability to grow at 45°C was also examined. None of the C. dubliniensis isolates grew at 45°C, and 23 of 100 C. albicans isolates (23%) exhibited poor or no growth at 45°C. The XYL and MDG tests contained within the API 20C AUX system were both negative for all 66 C. dubliniensis isolates and were positive for 98 (XYL) and 56 (MDG) of the 100 C. albicans isolates. With the Vitek system, 64 of 66 C. dubliniensis isolates (97.0%) were XYL negative and 63 (95.0%) were MDG negative. Conversely, 96 of 100 C. albicans isolates (96.0%) were XYL positive and 100 (100.0%) were MDG positive with the Vitek system. Clinical microbiology laboratories could use lack of growth at 45°C and a negative XYL test with either the API 20C AUX or Vitek yeast identification system to provide a presumptive identification of C. dubliniensis. A negative MDG test result with either system would also be helpful but may misclassify C. albicans as C. dubliniensis, especially when the API 20C AUX system is used. PMID:10565888

  14. Identification of Candida dubliniensis based on temperature and utilization of xylose and alpha-methyl-D-glucoside as determined with the API 20C AUX and vitek YBC systems.

    Science.gov (United States)

    Gales, A C; Pfaller, M A; Houston, A K; Joly, S; Sullivan, D J; Coleman, D C; Soll, D R

    1999-12-01

    To have a better understanding of the role of Candida dubliniensis in clinical infections, it is essential that microbiology laboratories can identify this species rapidly and accurately in clinical specimens. C. dubliniensis has been reported to lack the ability to utilize xylose (XYL) and alpha-methyl-D-glucoside (MDG) and to grow poorly or not at all at 45 degrees C, whereas Candida albicans isolates utilize XYL and MDG and usually grow well at 45 degrees C. We tested 66 isolates of C. dubliniensis and 100 isolates of C. albicans with both the API 20C AUX and Vitek YBC systems to evaluate the ability of the XYL and MDG tests contained within each of these systems to distinguish between the two species. The ability to grow at 45 degrees C was also examined. None of the C. dubliniensis isolates grew at 45 degrees C, and 23 of 100 C. albicans isolates (23%) exhibited poor or no growth at 45 degrees C. The XYL and MDG tests contained within the API 20C AUX system were both negative for all 66 C. dubliniensis isolates and were positive for 98 (XYL) and 56 (MDG) of the 100 C. albicans isolates. With the Vitek system, 64 of 66 C. dubliniensis isolates (97.0%) were XYL negative and 63 (95.0%) were MDG negative. Conversely, 96 of 100 C. albicans isolates (96.0%) were XYL positive and 100 (100.0%) were MDG positive with the Vitek system. Clinical microbiology laboratories could use lack of growth at 45 degrees C and a negative XYL test with either the API 20C AUX or Vitek yeast identification system to provide a presumptive identification of C. dubliniensis. A negative MDG test result with either system would also be helpful but may misclassify C. albicans as C. dubliniensis, especially when the API 20C AUX system is used.

  15. Selecting and controlling API crystal form for pharmaceutical development--strategies and processes.

    Science.gov (United States)

    Yin, Shawn X; Grosso, John A

    2008-11-01

    The success of designing, developing, manufacturing and introducing oral dosage forms of pharmaceutical products into the market relies on many steps, processes, stages and usually three phases of clinical trials. One key process is selecting an appropriate active pharmaceutical ingredient (API) crystal or amorphous form for the final dosage product: the ultimate goal of this selection process is to ensure that the manufactured product contains a stable and bioavailable active ingredient. A thorough knowledge of the solid-state chemistry of the API, the related excipients and the processes to make the product are critical in meeting this goal. Through recently published literature and the authors' experiences, this review describes the concepts and approaches that are used in the development of a truly knowledge-based crystalline API form selection process and highlights the appropriate studies which fit the Quality by Design (QbD) framework for pharmaceutical development activities. This review also discusses the potential API crystal form transformations in the API crystallization, post-crystallization and formulation stages, which are demonstrated by case study examples.

  16. A Fine-Grained API Link Prediction Approach Supporting CMDA Mashup Recommendation

    Science.gov (United States)

    Zhang, J.; Bao, Q.; Lee, T. J.; Ramachandran, R.; Lee, S.; Pan, L.; Gatlin, P. N.; Maskey, M.

    2017-12-01

    Service (API) discovery and recommendation is key to the wide spread of service oriented architecture and service oriented software engineering. Service recommendation typically relies on service linkage prediction calculated by the semantic distances (or similarities) among services based on their collection of inherent attributes. Given a specific context (mashup goal), however, different attributes may contribute differently to a service linkage. In this work, instead of training a model for all attributes as a whole, a novel approach is presented to simultaneously train separate models for individual attributes. Our contributions are summarized in three-fold. First is that we have developed a scalable attribute-level data model, featuring scalability and extensibility. We have extended Multiplicative Attribute Graph (MAG) model to represent node profiles featuring rich categorical attributes, while relaxing its constraint of requiring a priori knowledge of predefined attributes. LDA is leveraged to dynamically identify attributes based on attribute modeling, and multiple Gaussian fit is applied to find global optimal values. The second contribution is that we have seamlessly integrated the latent relationships between API attributes as well as observed network structure based on historical API usage data. Such a layered information model enables us to predict the probability of a link between two APIs based on their attribute link affinities carrying a variety of information including meta data, semantic data, historical usage data, as well as crowdsourcing user comments and annotations. The third contribution is that we have developed a finegrained context-aware mashup-API recommendation technique. On top of individual models trained for separate attributes, a dedicated layer is trained to represent the latent attribute distribution regarding mashup purpose, i.e., sensitivity of attributes to context. Thus, given the description of an intended mashup, the

  17. Mars Propellant Liquefaction and Storage Performance Modeling using Thermal Desktop with an Integrated Cryocooler Model

    Science.gov (United States)

    Desai, Pooja; Hauser, Dan; Sutherlin, Steven

    2017-01-01

    NASAs current Mars architectures are assuming the production and storage of 23 tons of liquid oxygen on the surface of Mars over a duration of 500+ days. In order to do this in a mass efficient manner, an energy efficient refrigeration system will be required. Based on previous analysis NASA has decided to do all liquefaction in the propulsion vehicle storage tanks. In order to allow for transient Martian environmental effects, a propellant liquefaction and storage system for a Mars Ascent Vehicle (MAV) was modeled using Thermal Desktop. The model consisted of a propellant tank containing a broad area cooling loop heat exchanger integrated with a reverse turbo Brayton cryocooler. Cryocooler sizing and performance modeling was conducted using MAV diurnal heat loads and radiator rejection temperatures predicted from a previous thermal model of the MAV. A system was also sized and modeled using an alternative heat rejection system that relies on a forced convection heat exchanger. Cryocooler mass, input power, and heat rejection for both systems were estimated and compared against sizing based on non-transient sizing estimates.

  18. Linked Vocabulary API for the Earth Sciences Community

    Science.gov (United States)

    Zednik, S.; Fox, P. A.; Fu, L.; West, P.; Ma, X.

    2014-12-01

    The Linked Vocabulary API is a specification for publishing RESTful APIs of vocabularies represented in the Simple Knowledge Organization System (SKOS) as Linked Data on the web. This work began as part of the Coastal and Marine Spatial Planning Vocabularies (CMSPV) project in response to the need for a standard manner for agencies to publish and consume hierarchical vocabularies on the web. The RESTful architecture of the API provides a simple mechanism for consumption of full vocabularies, single vocabulary terms, related terms, and searches on terms. The Linked Data nature of the API promotes interoperability by exposing vocabulary resources as resolvable URIs that may be referenced from other vocabularies or sources of Linked Data and by allowing the published vocabulary to contain references as links to terms from other vocabularies. The Linked Vocabulary API is formally defined in a Linked Data API specification and may be deployed using standard implementations of the Linked Data API such as the Epimorphics Linked Data API (ELDA). Recent presentations of work done with the Linked Vocabulary API as part of the CMSPV project have resulted in the API receiving growing interest from the broader scientific community. In this contribution we present the Linked Vocabulary API design and deployment process.

  19. Impact of Nosema ceranae and Nosema apis on individual worker bees of the two host species (Apis cerana and Apis mellifera) and regulation of host immune response.

    Science.gov (United States)

    Sinpoo, Chainarong; Paxton, Robert J; Disayathanoowat, Terd; Krongdang, Sasiprapa; Chantawannakul, Panuwan

    Nosema apis and Nosema ceranae are obligate intracellular microsporidian parasites infecting midgut epithelial cells of host adult honey bees, originally Apis mellifera and Apis cerana respectively. Each microsporidia cross-infects the other host and both microsporidia nowadays have a worldwide distribution. In this study, cross-infection experiments using both N. apis and N. ceranae in both A. mellifera and A. cerana were carried out to compare pathogen proliferation and impact on hosts, including host immune response. Infection by N. ceranae led to higher spore loads than by N. apis in both host species, and there was greater proliferation of microsporidia in A. mellifera compared to A. cerana. Both N. apis and N. ceranae were pathogenic in both host Apis species. N. ceranae induced subtly, though not significantly, higher mortality than N. apis in both host species, yet survival of A. cerana was no different to that of A. mellifera in response to N. apis or N. ceranae. Infections of both host species with N. apis and N. ceranae caused significant up-regulation of AMP genes and cellular mediated immune genes but did not greatly alter apoptosis-related gene expression. In this study, A. cerana enlisted a higher immune response and displayed lower loads of N. apis and N. ceranae spores than A. mellifera, suggesting it may be better able to defend itself against microsporidia infection. We caution against over-interpretation of our results, though, because differences between host and parasite species in survival were insignificant and because size differences between microsporidia species and between host Apis species may alternatively explain the differential proliferation of N. ceranae in A. mellifera. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Emissions of Ultrafine Particles and Volatile Organic Compounds from Commercially Available Desktop Three-Dimensional Printers with Multiple Filaments.

    Science.gov (United States)

    Azimi, Parham; Zhao, Dan; Pouzet, Claire; Crain, Neil E; Stephens, Brent

    2016-02-02

    Previous research has shown that desktop 3D printers can emit large numbers of ultrafine particles (UFPs, particles less than 100 nm) and some hazardous volatile organic compounds (VOCs) during printing, although very few filament and 3D printer combinations have been tested to date. Here we quantify emissions of UFPs and speciated VOCs from five commercially available filament extrusion desktop 3D printers utilizing up to nine different filaments by controlled experiments in a test chamber. Median estimates of time-varying UFP emission rates ranged from ∼10(8) to ∼10(11) min(-1) across all tested combinations, varying primarily by filament material and, to a lesser extent, bed temperature. The individual VOCs emitted in the largest quantities included caprolactam from nylon-based and imitation wood and brick filaments (ranging from ∼2 to ∼180 μg/min), styrene from acrylonitrile butadiene styrene (ABS) and high-impact polystyrene (HIPS) filaments (ranging from ∼10 to ∼110 μg/min), and lactide from polylactic acid (PLA) filaments (ranging from ∼4 to ∼5 μg/min). Results from a screening analysis of potential exposure to these products in a typical small office environment suggest caution should be used when operating many of the printer and filament combinations in poorly ventilated spaces or without the aid of combined gas and particle filtration systems.

  1. Testing the quality of images for permanent magnet desktop MRI systems using specially designed phantoms.

    Science.gov (United States)

    Qiu, Jianfeng; Wang, Guozhu; Min, Jiao; Wang, Xiaoyan; Wang, Pengcheng

    2013-12-21

    Our aim was to measure the performance of desktop magnetic resonance imaging (MRI) systems using specially designed phantoms, by testing imaging parameters and analysing the imaging quality. We designed multifunction phantoms with diameters of 18 and 60 mm for desktop MRI scanners in accordance with the American Association of Physicists in Medicine (AAPM) report no. 28. We scanned the phantoms with three permanent magnet 0.5 T desktop MRI systems, measured the MRI image parameters, and analysed imaging quality by comparing the data with the AAPM criteria and Chinese national standards. Image parameters included: resonance frequency, high contrast spatial resolution, low contrast object detectability, slice thickness, geometrical distortion, signal-to-noise ratio (SNR), and image uniformity. The image parameters of three desktop MRI machines could be measured using our specially designed phantoms, and most parameters were in line with MRI quality control criterion, including: resonance frequency, high contrast spatial resolution, low contrast object detectability, slice thickness, geometrical distortion, image uniformity and slice position accuracy. However, SNR was significantly lower than in some references. The imaging test and quality control are necessary for desktop MRI systems, and should be performed with the applicable phantom and corresponding standards.

  2. Reactome Pengine: A web-logic API to the homo sapiens reactome.

    Science.gov (United States)

    Neaves, Samuel R; Tsoka, Sophia; Millard, Louise A C

    2018-03-30

    Existing ways of accessing data from the Reactome database are limited. Either a researcher is restricted to particular queries defined by a web application programming interface (API), or they have to download the whole database. Reactome Pengine is a web service providing a logic programming based API to the human reactome. This gives researchers greater flexibility in data access than existing APIs, as users can send their own small programs (alongside queries) to Reactome Pengine. The server and an example notebook can be found at https://apps.nms.kcl.ac.uk/reactome-pengine. Source code is available at https://github.com/samwalrus/reactome-pengine and a Docker image is available at https://hub.docker.com/r/samneaves/rp4/ . samuel.neaves@kcl.ac.uk. Supplementary data are available at Bioinformatics online.

  3. Lowering the learning curve for declarative programming: a Python API for the IDP system

    OpenAIRE

    Vennekens, Joost

    2015-01-01

    Programmers may be hesitant to use declarative systems, because of the associated learning curve. In this paper, we present an API that integrates the IDP Knowledge Base system into the Python programming language. IDP is a state-of-the-art logical system, which uses SAT, SMT, Logic Programming and Answer Set Programming tech- nology. Python is currently one of the most widely used (teaching) lan- guages for programming. The first goal of our API is to allow a Python programmer to use the dec...

  4. Unique Methodologies for Nano/Micro Manufacturing Job Training Via Desktop Supercomputer Modeling and Simulation

    Energy Technology Data Exchange (ETDEWEB)

    Kimball, Clyde [Northern Illinois Univ., DeKalb, IL (United States); Karonis, Nicholas [Northern Illinois Univ., DeKalb, IL (United States); Lurio, Laurence [Northern Illinois Univ., DeKalb, IL (United States); Piot, Philippe [Northern Illinois Univ., DeKalb, IL (United States); Xiao, Zhili [Northern Illinois Univ., DeKalb, IL (United States); Glatz, Andreas [Northern Illinois Univ., DeKalb, IL (United States); Pohlman, Nicholas [Northern Illinois Univ., DeKalb, IL (United States); Hou, Minmei [Northern Illinois Univ., DeKalb, IL (United States); Demir, Veysel [Northern Illinois Univ., DeKalb, IL (United States); Song, Jie [Northern Illinois Univ., DeKalb, IL (United States); Duffin, Kirk [Northern Illinois Univ., DeKalb, IL (United States); Johns, Mitrick [Northern Illinois Univ., DeKalb, IL (United States); Sims, Thomas [Northern Illinois Univ., DeKalb, IL (United States); Yin, Yanbin [Northern Illinois Univ., DeKalb, IL (United States)

    2012-11-21

    This project establishes an initiative in high speed (Teraflop)/large-memory desktop supercomputing for modeling and simulation of dynamic processes important for energy and industrial applications. It provides a training ground for employment of current students in an emerging field with skills necessary to access the large supercomputing systems now present at DOE laboratories. It also provides a foundation for NIU faculty to quantum leap beyond their current small cluster facilities. The funding extends faculty and student capability to a new level of analytic skills with concomitant publication avenues. The components of the Hewlett Packard computer obtained by the DOE funds create a hybrid combination of a Graphics Processing System (12 GPU/Teraflops) and a Beowulf CPU system (144 CPU), the first expandable via the NIU GAEA system to ~60 Teraflops integrated with a 720 CPU Beowulf system. The software is based on access to the NVIDIA/CUDA library and the ability through MATLAB multiple licenses to create additional local programs. A number of existing programs are being transferred to the CPU Beowulf Cluster. Since the expertise necessary to create the parallel processing applications has recently been obtained at NIU, this effort for software development is in an early stage. The educational program has been initiated via formal tutorials and classroom curricula designed for the coming year. Specifically, the cost focus was on hardware acquisitions and appointment of graduate students for a wide range of applications in engineering, physics and computer science.

  5. Clinical predictors of the optimal spectacle correction for comfort performing desktop tasks.

    Science.gov (United States)

    Leffler, Christopher T; Davenport, Byrd; Rentz, Jodi; Miller, Amy; Benson, William

    2008-11-01

    The best strategy for spectacle correction of presbyopia for near tasks has not been determined. Thirty volunteers over the age of 40 years were tested for subjective accommodative amplitude, pupillary size, fusional vergence, interpupillary distance, arm length, preferred working distance, near and far visual acuity and preferred reading correction in the phoropter and trial frames. Subjects performed near tasks (reading, writing and counting change) using various spectacle correction strengths. Predictors of the correction maximising near task comfort were determined by multivariable linear regression. The mean age was 54.9 years (range 43 to 71) and 40 per cent had diabetes. Significant predictors of the most comfortable addition in univariate analyses were age (pphoropter (p=0.002) or trial frames (p0.15). The preferred addition wearing trial frames holding a reading target at a distance selected by the patient was the only independent predictor. Excluding this variable, distance visual acuity was predictive independent of age or near vision wearing distance correction. The distance selected for task performance was predicted by vision wearing distance correction at near and at distance. Multivariable linear regression can be used to generate tables based on distance visual acuity and age or near vision wearing distance correction to determine tentative near spectacle addition. Final spectacle correction for desktop tasks can be estimated by subjective refraction with trial frames.

  6. Population Genetics of Nosema apis and Nosema ceranae: One Host (Apis mellifera) and Two Different Histories

    Science.gov (United States)

    Maside, Xulio; Gómez-Moracho, Tamara; Jara, Laura; Martín-Hernández, Raquel; De la Rúa, Pilar; Higes, Mariano; Bartolomé, Carolina

    2015-01-01

    Two microsporidians are known to infect honey bees: Nosema apis and Nosema ceranae. Whereas population genetics data for the latter have been released in the last few years, such information is still missing for N. apis. Here we analyze the patterns of nucleotide polymorphism at three single-copy loci (PTP2, PTP3 and RPB1) in a collection of Apis mellifera isolates from all over the world, naturally infected either with N. apis (N = 22) or N. ceranae (N = 23), to provide new insights into the genetic diversity, demography and evolution of N. apis, as well as to compare them with evidence from N. ceranae. Neutral variation in N. apis and N. ceranae is of the order of 1%. This amount of diversity suggests that there is no substantial differentiation between the genetic content of the two nuclei present in these parasites, and evidence for genetic recombination provides a putative mechanism for the flow of genetic information between chromosomes. The analysis of the frequency spectrum of neutral variants reveals a significant surplus of low frequency variants, particularly in N. ceranae, and suggests that the populations of the two pathogens are not in mutation-drift equilibrium and that they have experienced a population expansion. Most of the variation in both species occurs within honey bee colonies (between 62%-90% of the total genetic variance), although in N. apis there is evidence for differentiation between parasites isolated from distinct A. mellifera lineages (20%-34% of the total variance), specifically between those collected from lineages A and C (or M). This scenario is consistent with a long-term host-parasite relationship and contrasts with the lack of differentiation observed among host-lineages in N. ceranae (mellifera worldwide population is a recent event. PMID:26720131

  7. An overview of the CellML API and its implementation

    Directory of Open Access Journals (Sweden)

    Halstead Matt

    2010-04-01

    Full Text Available Abstract Background CellML is an XML based language for representing mathematical models, in a machine-independent form which is suitable for their exchange between different authors, and for archival in a model repository. Allowing for the exchange and archival of models in a computer readable form is a key strategic goal in bioinformatics, because of the associated improvements in scientific record accuracy, the faster iterative process of scientific development, and the ability to combine models into large integrative models. However, for CellML models to be useful, tools which can process them correctly are needed. Due to some of the more complex features present in CellML models, such as imports, developing code ab initio to correctly process models can be an onerous task. For this reason, there is a clear and pressing need for an application programming interface (API, and a good implementation of that API, upon which tools can base their support for CellML. Results We developed an API which allows the information in CellML models to be retrieved and/or modified. We also developed a series of optional extension APIs, for tasks such as simplifying the handling of connections between variables, dealing with physical units, validating models, and translating models into different procedural languages. We have also provided a Free/Open Source implementation of this application programming interface, optimised to achieve good performance. Conclusions Tools have been developed using the API which are mature enough for widespread use. The API has the potential to accelerate the development of additional tools capable of processing CellML, and ultimately lead to an increased level of sharing of mathematical model descriptions.

  8. Hemolymph proteome changes during worker brood development match the biological divergences between western honey bees (Apis mellifera) and eastern honey bees (Apis cerana).

    Science.gov (United States)

    Feng, Mao; Ramadan, Haitham; Han, Bin; Fang, Yu; Li, Jianke

    2014-07-05

    Hemolymph plays key roles in honey bee molecule transport, immune defense, and in monitoring the physiological condition. There is a lack of knowledge regarding how the proteome achieves these biological missions for both the western and eastern honey bees (Apis mellifera and Apis cerana). A time-resolved proteome was compared using two-dimensional electrophoresis-based proteomics to reveal the mechanistic differences by analysis of hemolymph proteome changes between the worker bees of two bee species during the larval to pupal stages. The brood body weight of Apis mellifera was significantly heavier than that of Apis cerana at each developmental stage. Significantly, different protein expression patterns and metabolic pathways were observed in 74 proteins (166 spots) that were differentially abundant between the two bee species. The function of hemolymph in energy storage, odor communication, and antioxidation is of equal importance for the western and eastern bees, indicated by the enhanced expression of different protein species. However, stronger expression of protein folding, cytoskeletal and developmental proteins, and more highly activated energy producing pathways in western bees suggests that the different bee species have developed unique strategies to match their specific physiology using hemolymph to deliver nutrients and in immune defense. Our disparate findings constitute a proof-of-concept of molecular details that the ecologically shaped different physiological conditions of different bee species match with the hemolymph proteome during the brood stage. This also provides a starting point for future research on the specific hemolymph proteins or pathways related to the differential phenotypes or physiology.

  9. Developing a Process Model for the Forensic Extraction of Information from Desktop Search Applications

    Directory of Open Access Journals (Sweden)

    Timothy Pavlic

    2008-03-01

    Full Text Available Desktop search applications can contain cached copies of files that were deleted from the file system. Forensic investigators see this as a potential source of evidence, as documents deleted by suspects may still exist in the cache. Whilst there have been attempts at recovering data collected by desktop search applications, there is no methodology governing the process, nor discussion on the most appropriate means to do so. This article seeks to address this issue by developing a process model that can be applied when developing an information extraction application for desktop search applications, discussing preferred methods and the limitations of each. This work represents a more structured approach than other forms of current research.

  10. Genetic variation in natural honeybee populations, Apis mellifera capensis

    Science.gov (United States)

    Hepburn, Randall; Neumann, Peter; Radloff, Sarah E.

    2004-09-01

    Genetic variation in honeybee, Apis mellifera, populations can be considerably influenced by breeding and commercial introductions, especially in areas with abundant beekeeping. However, in southern Africa apiculture is based on the capture of wild swarms, and queen rearing is virtually absent. Moreover, the introduction of European subspecies constantly failed in the Cape region. We therefore hypothesize a low human impact on genetic variation in populations of Cape honeybees, Apis mellifera capensis. A novel solution to studying genetic variation in honeybee populations based on thelytokous worker reproduction is applied to test this hypothesis. Environmental effects on metrical morphological characters of the phenotype are separated to obtain a genetic residual component. The genetic residuals are then re-calculated as coefficients of genetic variation. Characters measured included hair length on the abdomen, width and length of wax plate, and three wing angles. The data show for the first time that genetic variation in Cape honeybee populations is independent of beekeeping density and probably reflects naturally occurring processes such as gene flow due to topographic and climatic variation on a microscale.

  11. Effects of Nosema apis, N. ceranae, and coinfections on honey bee (Apis mellifera) learning and memory.

    Science.gov (United States)

    Charbonneau, Lise R; Hillier, Neil Kirk; Rogers, Richard E L; Williams, Geoffrey R; Shutler, Dave

    2016-03-10

    Western honey bees (Apis mellifera) face an increasing number of challenges that in recent years have led to significant economic effects on apiculture, with attendant consequences for agriculture. Nosemosis is a fungal infection of honey bees caused by either Nosema apis or N. ceranae. The putative greater virulence of N. ceranae has spurred interest in understanding how it differs from N. apis. Little is known of effects of N. apis or N. ceranae on honey bee learning and memory. Following a Pavlovian model that relies on the proboscis extension reflex, we compared acquisition learning and long-term memory recall of uninfected (control) honey bees versus those inoculated with N. apis, N. ceranae, or both. We also tested whether spore intensity was associated with variation in learning and memory. Neither learning nor memory differed among treatments. There was no evidence of a relationship between spore intensity and learning, and only limited evidence of a negative effect on memory; this occurred only in the co-inoculation treatment. Our results suggest that if Nosema spp. are contributing to unusually high colony losses in recent years, the mechanism by which they may affect honey bees is probably not related to effects on learning or memory, at least as assessed by the proboscis extension reflex.

  12. Low-cost Method for Obtaining Medical Rapid Prototyping Using Desktop 3D printing: A Novel Technique for Mandibular Reconstruction Planning.

    Science.gov (United States)

    Velasco, Ignacio; Vahdani, Soheil; Ramos, Hector

    2017-09-01

    Three-dimensional (3D) printing is relatively a new technology with clinical applications, which enable us to create rapid accurate prototype of the selected anatomic region, making it possible to plan complex surgery and pre-bend hardware for individual surgical cases. This study aimed to express our experience with the use of medical rapid prototype (MRP) of the maxillofacial region created by desktop 3D printer and its application in maxillofacial reconstructive surgeries. Three patients with benign mandible tumors were included in this study after obtaining informed consent. All patient's maxillofacial CT scan data was processed by segmentation and isolation software and mandible MRP was printed using our desktop 3D printer. These models were used for preoperative surgical planning and prebending of the reconstruction plate. MRP created by desktop 3D printer is a cost-efficient, quick and easily produced appliance for the planning of reconstructive surgery. It can contribute in patient orientation and helping them in a better understanding of their condition and proposed surgical treatment. It helps surgeons for pre-operative planning in the resection or reconstruction cases and represent an excellent tool in academic setting for residents training. The pre-bended reconstruction plate based on MRP, resulted in decreased surgery time, cost and anesthesia risks on the patients. Key words: 3D printing, medical modeling, rapid prototype, mandibular reconstruction, ameloblastoma.

  13. A desktop 3D printer with dual extruders to produce customised electronic circuitry

    OpenAIRE

    Butt, Javaid; Onimowo, Dominic A.; Gohrabian, Mohammed; Sharma, Tinku; Shirvani, Hassan

    2018-01-01

    3D printing has opened new horizons for the manufacturing industry in general and 3D printers have become the tools for technological advancements. There is a huge divide between the pricing of industrial and desktop 3D printers with the former being on the expensive side capable of producing excellent quality products and latter being on the low-cost side with moderate quality results. However, there is a larger room for improvements and enhancements for the desktop systems as compared to th...

  14. Applications and a three-dimensional desktop environment for an immersive virtual reality system

    International Nuclear Information System (INIS)

    Kageyama, Akira; Masada, Youhei

    2013-01-01

    We developed an application launcher called Multiverse for scientific visualizations in a CAVE-type virtual reality (VR) system. Multiverse can be regarded as a type of three-dimensional (3D) desktop environment. In Multiverse, a user in a CAVE room can browse multiple visualization applications with 3D icons and explore movies that float in the air. Touching one of the movies causes ''teleportation'' into the application's VR space. After analyzing the simulation data using the application, the user can jump back into Multiverse's VR desktop environment in the CAVE

  15. Transcriptome analysis of the honey bee fungal pathogen, Ascosphaera apis: implications for host pathogenesis.

    Science.gov (United States)

    Cornman, R Scott; Bennett, Anna K; Murray, K Daniel; Evans, Jay D; Elsik, Christine G; Aronstein, Kate

    2012-06-29

    We present a comprehensive transcriptome analysis of the fungus Ascosphaera apis, an economically important pathogen of the Western honey bee (Apis mellifera) that causes chalkbrood disease. Our goals were to further annotate the A. apis reference genome and to identify genes that are candidates for being differentially expressed during host infection versus axenic culture. We compared A. apis transcriptome sequence from mycelia grown on liquid or solid media with that dissected from host-infected tissue. 454 pyrosequencing provided 252 Mb of filtered sequence reads from both culture types that were assembled into 10,087 contigs. Transcript contigs, protein sequences from multiple fungal species, and ab initio gene predictions were included as evidence sources in the Maker gene prediction pipeline, resulting in 6,992 consensus gene models. A phylogeny based on 12 of these protein-coding loci further supported the taxonomic placement of Ascosphaera as sister to the core Onygenales. Several common protein domains were less abundant in A. apis compared with related ascomycete genomes, particularly cytochrome p450 and protein kinase domains. A novel gene family was identified that has expanded in some ascomycete lineages, but not others. We manually annotated genes with homologs in other fungal genomes that have known relevance to fungal virulence and life history. Functional categories of interest included genes involved in mating-type specification, intracellular signal transduction, and stress response. Computational and manual annotations have been made publicly available on the Bee Pests and Pathogens website. This comprehensive transcriptome analysis substantially enhances our understanding of the A. apis genome and its expression during infection of honey bee larvae. It also provides resources for future molecular studies of chalkbrood disease and ultimately improved disease management.

  16. Transcriptome analysis of the honey bee fungal pathogen, Ascosphaera apis: implications for host pathogenesis

    Directory of Open Access Journals (Sweden)

    Cornman R

    2012-06-01

    Full Text Available Abstract Background We present a comprehensive transcriptome analysis of the fungus Ascosphaera apis, an economically important pathogen of the Western honey bee (Apis mellifera that causes chalkbrood disease. Our goals were to further annotate the A. apis reference genome and to identify genes that are candidates for being differentially expressed during host infection versus axenic culture. Results We compared A. apis transcriptome sequence from mycelia grown on liquid or solid media with that dissected from host-infected tissue. 454 pyrosequencing provided 252 Mb of filtered sequence reads from both culture types that were assembled into 10,087 contigs. Transcript contigs, protein sequences from multiple fungal species, and ab initio gene predictions were included as evidence sources in the Maker gene prediction pipeline, resulting in 6,992 consensus gene models. A phylogeny based on 12 of these protein-coding loci further supported the taxonomic placement of Ascosphaera as sister to the core Onygenales. Several common protein domains were less abundant in A. apis compared with related ascomycete genomes, particularly cytochrome p450 and protein kinase domains. A novel gene family was identified that has expanded in some ascomycete lineages, but not others. We manually annotated genes with homologs in other fungal genomes that have known relevance to fungal virulence and life history. Functional categories of interest included genes involved in mating-type specification, intracellular signal transduction, and stress response. Computational and manual annotations have been made publicly available on the Bee Pests and Pathogens website. Conclusions This comprehensive transcriptome analysis substantially enhances our understanding of the A. apis genome and its expression during infection of honey bee larvae. It also provides resources for future molecular studies of chalkbrood disease and ultimately improved disease management.

  17. The effects of honey (Apis dorsata) supplements on increased bone strength in ovariectomized rat as animal model of osteoporosis

    Science.gov (United States)

    Yudaniayanti, Ira Sari; Primarizky, Hardany; Nangoi, Lianny

    2018-04-01

    Osteoporosis is a chronic skeletal disease characterized by low bone mass and microarchitectural deterioration with a consequent increase in bone fragility and fracture risk. The aim of the study was to evaluate the effects of honey (Apis dorsata) supplements on increased bone strength in ovariectomized rat as animal models of osteoporosis. Twenty female rats at 3 months of age, weighing 150-200 g were used in the study. The rats were divided into five groups (n=4) : Sham operation group (SH); ovariectomy group no treatment(OVX); ovariectomy with treatment Apis dorsata 1g/Kg BW (AD-1); ovariectomy with treatment Apis dorsata 2g/Kg BW (AD-2); ovariectomy with treatment Apis dorsata 4g/Kg BW (AD-3). The treatment started to be given the next day after ovariectomy operation for 12 weeks. The Rats were sacrified within 12 weeks, and then the right femur were taken bone strength test. Based on the statistical analysis of the bone strength test, the greatest score belongs to the Sham operation group (SH) that have significant difference (pgroup and AD-1 group, but there was no significant difference with AD-2 and AD-3 (p>0,05). In conclusion, honey (Apis dorsata) supplements has the effect of increasing bone strength in ovariectomized rat as animal models of osteoporosis, so that honey (Apis dorsata) supplements has the potential to be used as an alternative treatment for osteoporosis.

  18. Novel insights into excipient effects on the biopharmaceutics of APIs from different BCS classes: Lactose in solid oral dosage forms.

    Science.gov (United States)

    Kubbinga, Marlies; Moghani, Laura; Langguth, Peter

    2014-09-30

    Excipients encompass a wide range of properties that are of importance for the resulting drug product. Regulatory guidelines on biowaivers for immediate release formulations require an in depth understanding of the biopharmaceutic effects of excipients in order to establish bioequivalence between two different products carrying the same API based on dissolution tests alone. This paper describes a new approach in evaluating biopharmaceutic excipient effects. Actually used quantities of a model excipient, lactose, formulated in combination with APIs from different BCS classes were evaluated. The results suggest that companies use different (relative) amounts depending on the characteristics of the API. The probability of bioinequivalence due to a difference in lactose content between test and reference products was classified as low for BCS class I APIs and medium for BCS class II and III APIs, whereas a high probability was assigned to the combination of lactose and BCS class IV APIs. If repeated for other excipients, this retrospective, top-down approach may lead to a new database and more widespread applications of the biowaiver approach. Copyright © 2014 Elsevier B.V. All rights reserved.

  19. Asteroids - NeoWs API

    Data.gov (United States)

    National Aeronautics and Space Administration — NeoWs (Near Earth Object Web Service) is a RESTful web service for near earth Asteroid information. With NeoWs a user can: search for Asteroids based on their...

  20. Survey of Public IaaS Cloud Computing API

    Science.gov (United States)

    Yamato, Yoji; Moriya, Takaaki; Ogawa, Takeshi; Akahani, Junichi

    Recently, Cloud computing is spread rapidly and many Cloud providers start their Cloud services. One of the Cloud computing problems is Cloud provider Lock In” for users. Actually, Cloud computing management APIs such as ordering or provisioning are different in each Cloud provider, so that users need to study and implement new APIs when they change Cloud providers. OGF and DMTF start the discussions of standardization of Cloud computing APIs, but there is no standard now. In this technical note, to clarify what APIs cloud providers should provide, we study common APIs for Cloud computing. We survey and compare Cloud computing APIs such as Rackspace Cloud Server, Sun Cloud, GoGrid, ElasticHosts, Amazon EC2 and FlexiScale which are currently provided as public IaaS Cloud APIs in the market. From the survey, the common APIs should support REST access style and provide account management, virtual server management, storage management, network management and resource usage management capabilities. We also show an example of OSS to provide these common APIs compared to normal hosting services OSS.

  1. Students' Beliefs about Mobile Devices vs. Desktop Computers in South Korea and the United States

    Science.gov (United States)

    Sung, Eunmo; Mayer, Richard E.

    2012-01-01

    College students in the United States and in South Korea completed a 28-item multidimensional scaling (MDS) questionnaire in which they rated the similarity of 28 pairs of multimedia learning materials on a 10-point scale (e.g., narrated animation on a mobile device Vs. movie clip on a desktop computer) and a 56-item semantic differential…

  2. Preparatory Study for the Design of a Desktop Videoconferencing Platform for Synchronous Language Teaching

    Science.gov (United States)

    Guichon, Nicolas

    2010-01-01

    This case study paves the way for a research and development project aiming to design a desktop videoconferencing platform specifically dedicated to synchronous language teaching. It starts by defining a model of language pedagogy adapted to distance and taking into account the affordances of videoconferencing for language teaching. It then…

  3. A Cross-Case Analysis of Gender Issues in Desktop Virtual Reality Learning Environments

    Science.gov (United States)

    Ausburn, Lynna J.; Martens, Jon; Washington, Andre; Steele, Debra; Washburn, Earlene

    2009-01-01

    This study examined gender-related issues in using new desktop virtual reality (VR) technology as a learning tool in career and technical education (CTE). Using relevant literature, theory, and cross-case analysis of data and findings, the study compared and analyzed the outcomes of two recent studies conducted by a research team at Oklahoma State…

  4. How Simulator Interfaces Affect Transfer of Training: Comparing Wearable and Desktop Systems

    Science.gov (United States)

    2012-06-01

    a keyboard and mouse to control a virtual Soldier. The desktop computers used were Dell XPS systems, with a 2.66 GHz Intel Core 2 Duo CPU, 4 GB of...significantly slower to complete the scenarios than the control condition, with the magnitude of this difference diminishing over time. 15 . SUBJECT... 15 ACRONYMS

  5. Randomized Trial of Desktop Humidifier for Dry Eye Relief in Computer Users.

    Science.gov (United States)

    Wang, Michael T M; Chan, Evon; Ea, Linda; Kam, Clifford; Lu, Yvonne; Misra, Stuti L; Craig, Jennifer P

    2017-11-01

    Dry eye is a frequently reported problem among computer users. Low relative humidity environments are recognized to exacerbate signs and symptoms of dry eye, yet are common in offices of computer operators. Desktop USB-powered humidifiers are available commercially, but their efficacy for dry eye relief has not been established. This study aims to evaluate the potential for a desktop USB-powered humidifier to improve tear-film parameters, ocular surface characteristics, and subjective comfort of computer users. Forty-four computer users were enrolled in a prospective, masked, randomized crossover study. On separate days, participants were randomized to 1 hour of continuous computer use, with and without exposure to a desktop humidifier. Lipid-layer grade, noninvasive tear-film breakup time, and tear meniscus height were measured before and after computer use. Following the 1-hour period, participants reported whether ocular comfort was greater, equal, or lesser than that at baseline. The desktop humidifier effected a relative difference in humidity between the two environments of +5.4 ± 5.0% (P .05). However, a relative increase in the median noninvasive tear-film breakup time of +4.0 seconds was observed in the humidified environment (P computer use.Trial registration no: ACTRN12617000326392.

  6. Negotiation of Meaning in Desktop Videoconferencing-Supported Distance Language Learning

    Science.gov (United States)

    Wang, Yuping

    2006-01-01

    The aim of this research is to reveal the dynamics of focus on form in task completion via videoconferencing. This examination draws on current second language learning theories regarding effective language acquisition, research in Computer Mediated Communication (CMC) and empirical data from an evaluation of desktop videoconferencing-supported…

  7. Multimodal Language Learner Interactions via Desktop Videoconferencing within a Framework of Social Presence: Gaze

    Science.gov (United States)

    Satar, H. Muge

    2013-01-01

    Desktop videoconferencing (DVC) offers many opportunities for language learning through its multimodal features. However, it also brings some challenges such as gaze and mutual gaze, that is, eye-contact. This paper reports some of the findings of a PhD study investigating social presence in DVC interactions of English as a Foreign Language (EFL)…

  8. The Use of the Webcam for Teaching a Foreign Language in a Desktop Videoconferencing Environment

    Science.gov (United States)

    Develotte, Christine; Guichon, Nicolas; Vincent, Caroline

    2010-01-01

    This paper explores how language teachers learn to teach with a synchronous multimodal setup ("Skype"), and it focuses on their use of the webcam during the pedagogical interaction. First, we analyze the ways that French graduate students learning to teach online use the multimodal resources available in a desktop videoconferencing (DVC)…

  9. Desktop Virtual Reality: A Powerful New Technology for Teaching and Research in Industrial Teacher Education

    Science.gov (United States)

    Ausburn, Lynna J.; Ausburn, Floyd B.

    2004-01-01

    Virtual Reality has been defined in many different ways and now means different things in various contexts. VR can range from simple environments presented on a desktop computer to fully immersive multisensory environments experienced through complex headgear and bodysuits. In all of its manifestations, VR is basically a way of simulating or…

  10. Using M@th Desktop Notebooks and Palettes in the Classroom

    Science.gov (United States)

    Simonovits, Reinhard

    2011-01-01

    This article explains the didactical design of M@th Desktop (MD), a teaching and learning software application for high schools and universities. The use of two types of MD resources is illustrated: notebooks and palettes, focusing on the topic of exponential functions. The handling of MD in a blended learning approach and the impact on the…

  11. Cybersickness and desktop simulations : Field of view effects and user experience

    NARCIS (Netherlands)

    Toet, Alexander; De Vries, Sjoerd C.; Van Emmerik, Martijn L.; Bos, Jelte E.

    2008-01-01

    We used a desktop computer game environment to study the effect Field-of-View (FOV) on cybersickness. In particular, we examined the effect of differences between the internal FOV (iFOV, the FOV which the graphics generator is using to render its images) and the external FOV (eFOV, the FOV of the

  12. Cybersickness and desktop simulations : field of view effects and user experience

    NARCIS (Netherlands)

    Toet, A.; Vries, S.C. de; Emmerik, M.L. van; Bos, J.E.

    2008-01-01

    We used a desktop computer game environment to study the effect Field-of-View (FOV) on cybersickness. In particular, we examined the effect of differences between the internal FOV (iFOV, the FOV which the graphics generator is using to render its images) and the external FOV (eFOV, the FOV of the

  13. Generating Alternative Engineering Designs by Integrating Desktop VR with Genetic Algorithms

    Science.gov (United States)

    Chandramouli, Magesh; Bertoline, Gary; Connolly, Patrick

    2009-01-01

    This study proposes an innovative solution to the problem of multiobjective engineering design optimization by integrating desktop VR with genetic computing. Although, this study considers the case of construction design as an example to illustrate the framework, this method can very much be extended to other engineering design problems as well.…

  14. Use of Signaling to Integrate Desktop Virtual Reality and Online Learning Management Systems

    Science.gov (United States)

    Dodd, Bucky J.; Antonenko, Pavlo D.

    2012-01-01

    Desktop virtual reality is an emerging educational technology that offers many potential benefits for learners in online learning contexts; however, a limited body of research is available that connects current multimedia learning techniques with these new forms of media. Because most formal online learning is delivered using learning management…

  15. GTfold: Enabling parallel RNA secondary structure prediction on multi-core desktops

    DEFF Research Database (Denmark)

    Swenson, M Shel; Anderson, Joshua; Ash, Andrew

    2012-01-01

    achieved significant improvements in runtime, but their implementations were not portable from niche high-performance computers or easily accessible to most RNA researchers. With the increasing prevalence of multi-core desktop machines, a new parallel prediction program is needed to take full advantage...

  16. Campus Computing 1992. The EDUCOM-USC Survey of Desktop Computing in Higher Education.

    Science.gov (United States)

    Green, Kenneth C.; Eastman, Skip

    A national survey of desktop computing in higher education was conducted in 1992 of 2500 institutions. Data were responses from public and private research universities, public and private four-year colleges, and community colleges. Respondents (N=970) were individuals specifically responsible for the operation and future direction of academic…

  17. Campus Computing 1993. The USC National Survey of Desktop Computing in Higher Education.

    Science.gov (United States)

    Green, Kenneth C.; Eastman, Skip

    A national survey of desktop computing in higher education was conducted in spring and summer 1993 at over 2500 institutions. Data were responses from public and private research universities, public and private four-year colleges and community colleges. Respondents (N=1011) were individuals specifically responsible for the operation and future…

  18. Campus Computing 1991. The EDUCOM-USC Survey of Desktop Computing in Higher Education.

    Science.gov (United States)

    Green, Kenneth C.; Eastman, Skip

    A national survey of desktop computing in higher education was conducted in 1991 of 2500 institutions. Data were responses from public and private research universities, public and private four-year colleges, and community colleges. Respondents (N=1099) were individuals specifically responsible for the operation and future direction of academic…

  19. From Server to Desktop: Capital and Institutional Planning for Client/Server Technology.

    Science.gov (United States)

    Mullig, Richard M.; Frey, Keith W.

    1994-01-01

    Beginning with a request for an enhanced system for decision/strategic planning support, the University of Chicago's biological sciences division has developed a range of administrative client/server tools, instituted a capital replacement plan for desktop technology, and created a planning and staffing approach enabling rapid introduction of new…

  20. Meaning-Making in Online Language Learner Interactions via Desktop Videoconferencing

    Science.gov (United States)

    Satar, H. Müge

    2016-01-01

    Online language learning and teaching in multimodal contexts has been identified as one of the key research areas in computer-aided learning (CALL) (Lamy, 2013; White, 2014). This paper aims to explore meaning-making in online language learner interactions via desktop videoconferencing (DVC) and in doing so illustrate multimodal transcription and…

  1. fine-GRAPE: Fine-grained APi usage extractor – an approach and dataset to investigate API usage

    OpenAIRE

    Sawant, A.A.; Bacchelli, A.

    2017-01-01

    An Application Programming Interface (API) provides a set of functionalities to a developer with the aim of enabling reuse. APIs have been investigated from different angles such as popularity usage and evolution to get a better understanding of their various characteristics. For such studies, software repositories are mined for API usage examples. However, many of the mining algorithms used for such purposes do not take type information into account. Thus making the results unreliable. In th...

  2. API, Cloud computing, WebGIS and cartography

    Directory of Open Access Journals (Sweden)

    Andrea Favretto

    2013-05-01

    Full Text Available This paper explores some of the digital mapping processes available on the Internet in order to analyse their cartographic congruence. It will focus on WebGIS-based cartography in relation to what is produced using Mash-up site maps. These websites often use Googlebased maps in order to produce their own cartography. Thus, we can identify two main typologies of Internet mapping sites, which are characterized by the ownership or non-ownership of their cartographic bases. This paper will critically assess the cartography employed in the two different instances. A concise introduction to the Cloud Computing Internet propagated phenomenon is also premised in order to provide the reader with an accurate frame of reference. Cloud Computing has encouraged a significant Internet participation via the Application Programming Interface software (API, leading to mash-up cartographic websites.

  3. Beebread from Apis mellifera and Apis dorsata. Comparative Chemical Composition and Bioactivity

    Directory of Open Access Journals (Sweden)

    Otilia BOBIS

    2017-05-01

    Full Text Available Beebread is a valuable bee product, both for bee nutrition and for humans. The high nutritional and bioactive properties of beebread were evaluated by chemical composition analysis of beebread from Apis mellifera and Apis dorsata. Bee bread harvested from Romania and India, coming from Apis mellifera and Apis dorsata bees, were evaluated for their chemical composition. Analyses were made in APHIS Laboratory from USAMV Cluj, using validated methods for bee products. Lipids were determined by the Soxhlet extraction method, total protein content was determined by Kjehldahl method, sugar spectrum was determined by high performance liquid chromatography with refractive index detection (HPLC-IR. Water content of beebread samples were situated between 11.45 and 16.46%, total protein content between 16.84 and 19.19% and total lipids between 6.36 and 13.47%.  Beebread has high bioactive properties which can be expressed as antioxidant and/or antibacterial activity. Chemical composition and bioactive properties of beebread is influenced by floral origin of the pollen which the bees collect and place in combs for fermentation. Also the climatic conditions have an important role in developing different fermentation compounds, that may act as antioxidants or antibacterial agents.

  4. From the desktop to the grid: scalable bioinformatics via workflow conversion.

    Science.gov (United States)

    de la Garza, Luis; Veit, Johannes; Szolek, Andras; Röttig, Marc; Aiche, Stephan; Gesing, Sandra; Reinert, Knut; Kohlbacher, Oliver

    2016-03-12

    Reproducibility is one of the tenets of the scientific method. Scientific experiments often comprise complex data flows, selection of adequate parameters, and analysis and visualization of intermediate and end results. Breaking down the complexity of such experiments into the joint collaboration of small, repeatable, well defined tasks, each with well defined inputs, parameters, and outputs, offers the immediate benefit of identifying bottlenecks, pinpoint sections which could benefit from parallelization, among others. Workflows rest upon the notion of splitting complex work into the joint effort of several manageable tasks. There are several engines that give users the ability to design and execute workflows. Each engine was created to address certain problems of a specific community, therefore each one has its advantages and shortcomings. Furthermore, not all features of all workflow engines are royalty-free -an aspect that could potentially drive away members of the scientific community. We have developed a set of tools that enables the scientific community to benefit from workflow interoperability. We developed a platform-free structured representation of parameters, inputs, outputs of command-line tools in so-called Common Tool Descriptor documents. We have also overcome the shortcomings and combined the features of two royalty-free workflow engines with a substantial user community: the Konstanz Information Miner, an engine which we see as a formidable workflow editor, and the Grid and User Support Environment, a web-based framework able to interact with several high-performance computing resources. We have thus created a free and highly accessible way to design workflows on a desktop computer and execute them on high-performance computing resources. Our work will not only reduce time spent on designing scientific workflows, but also make executing workflows on remote high-performance computing resources more accessible to technically inexperienced users. We

  5. Characterization of emissions from a desktop 3D printer and indoor air measurements in office settings.

    Science.gov (United States)

    Steinle, Patrick

    2016-01-01

    Emissions from a desktop 3D printer based on fused deposition modeling (FDM) technology were measured in a test chamber and indoor air was monitored in office settings. Ultrafine aerosol (UFA) emissions were higher while printing a standard object with polylactic acid (PLA) than with acrylonitrile butadiene styrene (ABS) polymer (2.1 × 10(9) vs. 2.4 × 10(8) particles/min). Prolonged use of the printer led to higher emission rates (factor 2 with PLA and 4 with ABS, measured after seven months of occasional use). UFA consisted mainly of volatile droplets, and some small (100-300 nm diameter) iron containing and soot-like particles were found. Emissions of inhalable and respirable dust were below the limit of detection (LOD) when measured gravimetrically, and only slightly higher than background when measured with an aerosol spectrometer. Emissions of volatile organic compounds (VOC) were in the range of 10 µg/min. Styrene accounted for more than 50% of total VOC emitted when printing with ABS; for PLA, methyl methacrylate (MMA, 37% of TVOC) was detected as the predominant compound. Two polycyclic aromatic hydrocarbons (PAH), fluoranthene and pyrene, were observed in very low amounts. All other analyzed PAH, as well as inorganic gases and metal emissions except iron (Fe) and zinc (Zn), were below the LOD or did not differ from background without printing. A single 3D print (165 min) in a large, well-ventilated office did not significantly increase the UFA and VOC concentrations, whereas these were readily detectable in a small, unventilated room, with UFA concentrations increasing by 2,000 particles/cm(3) and MMA reaching a peak of 21 µg/m(3) and still being detectable in the room even 20 hr after printing.

  6. Rare royal families in honeybees, Apis mellifera

    Science.gov (United States)

    Moritz, Robin F. A.; Lattorff, H. Michael G.; Neumann, Peter; Kraus, F. Bernhard; Radloff, Sarah E.; Hepburn, H. Randall

    2005-10-01

    The queen is the dominant female in the honeybee colony, Apis mellifera, and controls reproduction. Queen larvae are selected by the workers and are fed a special diet (royal jelly), which determines caste. Because queens mate with many males a large number of subfamilies coexist in the colony. As a consequence, there is a considerable potential for conflict among the subfamilies over queen rearing. Here we show that honeybee queens are not reared at random but are preferentially reared from rare “royal” subfamilies, which have extremely low frequencies in the colony's worker force but a high frequency in the queens reared.

  7. Efficiency using computer simulation of Reverse Threshold Model Theory on assessing a “One Laptop Per Child” computer versus desktop computer

    Directory of Open Access Journals (Sweden)

    Supat Faarungsang

    2017-04-01

    Full Text Available The Reverse Threshold Model Theory (RTMT model was introduced based on limiting factor concepts, but its efficiency compared to the Conventional Model (CM has not been published. This investigation assessed the efficiency of RTMT compared to CM using computer simulation on the “One Laptop Per Child” computer and a desktop computer. Based on probability values, it was found that RTMT was more efficient than CM among eight treatment combinations and an earlier study verified that RTMT gives complete elimination of random error. Furthermore, RTMT has several advantages over CM and is therefore proposed to be applied to most research data.

  8. Enabling Mobile Air Quality App Development with an AirNow API

    Science.gov (United States)

    Dye, T.; White, J. E.; Ludewig, S. A.; Dickerson, P.; Healy, A. N.; West, J. W.; Prince, L. A.

    2013-12-01

    The U.S. Environmental Protection Agency's (EPA) AirNow program works with over 130 participating state, local, and federal air quality agencies to obtain, quality control, and store real-time air quality observations and forecasts. From these data, the AirNow system generates thousands of maps and products each hour. Each day, information from AirNow is published online and in other media to assist the public in making health-based decisions related to air quality. However, an increasing number of people use mobile devices as their primary tool for obtaining information, and AirNow has responded to this trend by publishing an easy-to-use Web API that is useful for mobile app developers. This presentation will describe the various features of the AirNow application programming interface (API), including Representational State Transfer (REST)-type web services, file outputs, and RSS feeds. In addition, a web portal for the AirNow API will be shown, including documentation on use of the system, a query tool for configuring and running web services, and general information about the air quality data and forecasts available. Data published via the AirNow API includes corresponding Air Quality Index (AQI) levels for each pollutant. We will highlight examples of mobile apps that are using the AirNow API to provide location-based, real-time air quality information. Examples will include mobile apps developed for Minnesota ('Minnesota Air') and Washington, D.C. ('Clean Air Partners Air Quality'), and an app developed by EPA ('EPA AirNow').

  9. Experience API: Flexible, Decentralized and Activity-Centric Data Collection

    Science.gov (United States)

    Kevan, Jonathan M.; Ryan, Paul R.

    2016-01-01

    This emerging technology report describes the Experience API (xAPI), a new e-learning specification designed to support the learning community in standardizing and collecting both formal and informal distributed learning activities. Informed by Activity Theory, a framework aligned with constructivism, data is collected in the form of activity…

  10. Correlation between National Influenza Surveillance Data and Search Queries from Mobile Devices and Desktops in South Korea.

    Science.gov (United States)

    Shin, Soo-Yong; Kim, Taerim; Seo, Dong-Woo; Sohn, Chang Hwan; Kim, Sung-Hoon; Ryoo, Seung Mok; Lee, Yoon-Seon; Lee, Jae Ho; Kim, Won Young; Lim, Kyoung Soo

    2016-01-01

    Digital surveillance using internet search queries can improve both the sensitivity and timeliness of the detection of a health event, such as an influenza outbreak. While it has recently been estimated that the mobile search volume surpasses the desktop search volume and mobile search patterns differ from desktop search patterns, the previous digital surveillance systems did not distinguish mobile and desktop search queries. The purpose of this study was to compare the performance of mobile and desktop search queries in terms of digital influenza surveillance. The study period was from September 6, 2010 through August 30, 2014, which consisted of four epidemiological years. Influenza-like illness (ILI) and virologic surveillance data from the Korea Centers for Disease Control and Prevention were used. A total of 210 combined queries from our previous survey work were used for this study. Mobile and desktop weekly search data were extracted from Naver, which is the largest search engine in Korea. Spearman's correlation analysis was used to examine the correlation of the mobile and desktop data with ILI and virologic data in Korea. We also performed lag correlation analysis. We observed that the influenza surveillance performance of mobile search queries matched or exceeded that of desktop search queries over time. The mean correlation coefficients of mobile search queries and the number of queries with an r-value of ≥ 0.7 equaled or became greater than those of desktop searches over the four epidemiological years. A lag correlation analysis of up to two weeks showed similar trends. Our study shows that mobile search queries for influenza surveillance have equaled or even become greater than desktop search queries over time. In the future development of influenza surveillance using search queries, the recognition of changing trend of mobile search data could be necessary.

  11. Correlation between National Influenza Surveillance Data and Search Queries from Mobile Devices and Desktops in South Korea.

    Directory of Open Access Journals (Sweden)

    Soo-Yong Shin

    Full Text Available Digital surveillance using internet search queries can improve both the sensitivity and timeliness of the detection of a health event, such as an influenza outbreak. While it has recently been estimated that the mobile search volume surpasses the desktop search volume and mobile search patterns differ from desktop search patterns, the previous digital surveillance systems did not distinguish mobile and desktop search queries. The purpose of this study was to compare the performance of mobile and desktop search queries in terms of digital influenza surveillance.The study period was from September 6, 2010 through August 30, 2014, which consisted of four epidemiological years. Influenza-like illness (ILI and virologic surveillance data from the Korea Centers for Disease Control and Prevention were used. A total of 210 combined queries from our previous survey work were used for this study. Mobile and desktop weekly search data were extracted from Naver, which is the largest search engine in Korea. Spearman's correlation analysis was used to examine the correlation of the mobile and desktop data with ILI and virologic data in Korea. We also performed lag correlation analysis. We observed that the influenza surveillance performance of mobile search queries matched or exceeded that of desktop search queries over time. The mean correlation coefficients of mobile search queries and the number of queries with an r-value of ≥ 0.7 equaled or became greater than those of desktop searches over the four epidemiological years. A lag correlation analysis of up to two weeks showed similar trends.Our study shows that mobile search queries for influenza surveillance have equaled or even become greater than desktop search queries over time. In the future development of influenza surveillance using search queries, the recognition of changing trend of mobile search data could be necessary.

  12. The geospatial data quality REST API for primary biodiversity data.

    Science.gov (United States)

    Otegui, Javier; Guralnick, Robert P

    2016-06-01

    We present a REST web service to assess the geospatial quality of primary biodiversity data. It enables access to basic and advanced functions to detect completeness and consistency issues as well as general errors in the provided record or set of records. The API uses JSON for data interchange and efficient parallelization techniques for fast assessments of large datasets. The Geospatial Data Quality API is part of the VertNet set of APIs. It can be accessed at http://api-geospatial.vertnet-portal.appspot.com/geospatial and is already implemented in the VertNet data portal for quality reporting. Source code is freely available under GPL license from http://www.github.com/vertnet/api-geospatial javier.otegui@gmail.com or rguralnick@flmnh.ufl.edu Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press.

  13. Investigating an API for resilient exascale computing.

    Energy Technology Data Exchange (ETDEWEB)

    Stearley, Jon R.; Tomkins, James; VanDyke, John P.; Ferreira, Kurt Brian; Laros, James H.,; Bridges, Patrick

    2013-05-01

    Increased HPC capability comes with increased complexity, part counts, and fault occurrences. In- creasing the resilience of systems and applications to faults is a critical requirement facing the viability of exascale systems, as the overhead of traditional checkpoint/restart is projected to outweigh its bene ts due to fault rates outpacing I/O bandwidths. As faults occur and propagate throughout hardware and software layers, pervasive noti cation and handling mechanisms are necessary. This report describes an initial investigation of fault types and programming interfaces to mitigate them. Proof-of-concept APIs are presented for the frequent and important cases of memory errors and node failures, and a strategy proposed for lesystem failures. These involve changes to the operating system, runtime, I/O library, and application layers. While a single API for fault handling among hardware and OS and application system-wide remains elusive, the e ort increased our understanding of both the mountainous challenges and the promising trailheads. 3

  14. Hymenoptera venom review focusing on Apis mellifera

    Directory of Open Access Journals (Sweden)

    P. R. de Lima

    2003-01-01

    Full Text Available Hymenoptera venoms are complex mixtures containing simple organic molecules, proteins, peptides, and other bioactive elements. Several of these components have been isolated and characterized, and their primary structures determined by biochemical techniques. These compounds are responsible for many toxic or allergic reactions in different organisms, such as local pain, inflammation, itching, irritation, and moderate or severe allergic reactions. The most extensively characterized Hymenoptera venoms are bee venoms, mainly from the Apis genus and also from social wasps and ant species. However, there is little information about other Hymenoptera groups. The Apis venom presents high molecular weight molecules - enzymes with a molecular weight higher than 10.0 kDa - and peptides. The best studied enzymes are phospholipase A2, responsible for cleaving the membrane phospholipids, hyaluronidase, which degrades the matrix component hyaluronic acid into non-viscous segments and acid phosphatase acting on organic phosphates. The main peptide compounds of bee venom are lytic peptide melittin, apamin (neurotoxic, and mastocyte degranulating peptide (MCD.

  15. The desktop muon detector: A simple, physics-motivated machine- and electronics-shop project for university students

    Science.gov (United States)

    Axani, S. N.; Conrad, J. M.; Kirby, C.

    2017-12-01

    This paper describes the construction of a desktop muon detector, an undergraduate-level physics project that develops machine-shop and electronics-shop technical skills. The desktop muon detector is a self-contained apparatus that employs a plastic scintillator as the detection medium and a silicon photomultiplier for light collection. This detector can be battery powered and is used in conjunction with the provided software. The total cost per detector is approximately 100. We describe physics experiments we have performed, and then suggest several other interesting measurements that are possible, with one or more desktop muon detectors.

  16. fine-GRAPE : Fine-grained APi usage extractor – an approach and dataset to investigate API usage

    NARCIS (Netherlands)

    Sawant, A.A.; Bacchelli, A.

    An Application Programming Interface (API) provides a set of functionalities to a developer with the aim of enabling reuse. APIs have been investigated from different angles such as popularity usage and evolution to get a better understanding of their various characteristics. For such studies,

  17. Coming 5th Edition of the API Standard 618: major changes compared to the API 618, 4th edition

    NARCIS (Netherlands)

    Pyle, A.; Eijk, A.; Elferink, H.

    2003-01-01

    This paper will present the highlights of changes that will be found in the 5th Edition of API 618, which is expected to be published in late 2003 or early 2004. Approximately every 5 years the API Standards are revised in such a way that the latest field experiences and proven designs are included

  18. Gas chromatography coupled to atmospheric pressure ionization mass spectrometry (GC-API-MS): Review

    International Nuclear Information System (INIS)

    Li, Du-Xin; Gan, Lin; Bronja, Amela; Schmitz, Oliver J.

    2015-01-01

    Although the coupling of GC/MS with atmospheric pressure ionization (API) has been reported in 1970s, the interest in coupling GC with atmospheric pressure ion source was expanded in the last decade. The demand of a “soft” ion source for preserving highly diagnostic molecular ion is desirable, as compared to the “hard” ionization technique such as electron ionization (EI) in traditional GC/MS, which fragments the molecule in an extensive way. These API sources include atmospheric pressure chemical ionization (APCI), atmospheric pressure photoionization (APPI), atmospheric pressure laser ionization (APLI), electrospray ionization (ESI) and low temperature plasma (LTP). This review discusses the advantages and drawbacks of this analytical platform. After an introduction in atmospheric pressure ionization the review gives an overview about the history and explains the mechanisms of various atmospheric pressure ionization techniques used in combination with GC such as APCI, APPI, APLI, ESI and LTP. Also new developments made in ion source geometry, ion source miniaturization and multipurpose ion source constructions are discussed and a comparison between GC-FID, GC-EI-MS and GC-API-MS shows the advantages and drawbacks of these techniques. The review ends with an overview of applications realized with GC-API-MS. - Highlights: • Atmospheric pressure ion sources (APCI, ESI, APPI, APLC etc) enable the coupling of LC-based high-end MS to GC. • APIs show advantages in selectivity and sensitivity compared with EI in GC-MS. • Accurate mass database in GC-APCI/MS is emerging as an alternative to GC-EI/MS database.

  19. A Five-Year Hedonic Price Breakdown for Desktop Personal Computer Attributes in Brazil

    Directory of Open Access Journals (Sweden)

    Nuno Manoel Martins Dias Fouto

    2009-07-01

    Full Text Available The purpose of this article is to identify the attributes that discriminate the prices of personal desktop computers. We employ the hedonic price method in evaluating such characteristics. This approach allows market prices to be expressed as a function, a set of attributes present in the products and services offered. Prices and characteristics of up to 3,779 desktop personal computers offered in the IT pages of one of the main Brazilian newspapers were collected from January 2003 to December 2007. Several specifications for the hedonic (multivariate linear regression were tested. In this particular study, the main attributes were found to be hard drive capacity, screen technology, main board brand, random memory size, microprocessor brand, video board memory, digital video and compact disk recording devices, screen size and microprocessor speed. These results highlight the novel contribution of this study: the manner and means in which hedonic price indexes may be estimated in Brazil.

  20. Nuclear Plant Analyzer desktop workstation: An integrated interactive simulation, visualization and analysis tool

    International Nuclear Information System (INIS)

    Beelman, R.J.

    1991-01-01

    The advanced, best-estimate, reactor thermal-hydraulic codes were originally developed as mainframe computer applications because of speed, precision, memory and mass storage requirements. However, the productivity of numerical reactor safety analysts has historically been hampered by mainframe dependence due to limited mainframe CPU allocation, accessibility and availability, poor mainframe job throughput, and delays in obtaining and difficulty comprehending printed numerical results. The Nuclear Plant Analyzer (NPA) was originally developed as a mainframe computer-graphics aid for reactor safety analysts in addressing the latter consideration. Rapid advances in microcomputer technology have since enabled the installation and execution of these reactor safety codes on desktop computers thereby eliminating mainframe dependence. The need for a complementary desktop graphics display generation and presentation capability, coupled with the need for software standardization and portability, has motivated the redesign of the NPA as a UNIX/X-Windows application suitable for both mainframe and microcomputer

  1. Telemedicine in rural areas. Experience with medical desktop-conferencing via satellite.

    Science.gov (United States)

    Ricke, J; Kleinholz, L; Hosten, N; Zendel, W; Lemke, A; Wielgus, W; Vöge, K H; Fleck, E; Marciniak, R; Felix, R

    1995-01-01

    Cooperation between physicians in hospitals in rural areas can be assisted by desktop-conferencing using a satellite link. For six weeks, medical desktop-conferencing was tested during daily clinical conferences between the Virchow-Klinikum, Berlin, and the Medical Academy, Wroclaw. The communications link was provided by the German Telekom satellite system MCS, which allowed temporary connections to be established on demand by manual dialling. Standard hardware and software were used for videoconferencing, as well as software for medical communication developed in the BERMED project. Digital data, such as computed tomography or magnetic resonance images, were transmitted by a digital data channel in parallel to the transmission of analogue video and audio signals. For conferences involving large groups of people, hardware modifications were required. These included the installation of a video projector, adaptation of the audio system with improved echo cancellation, and installation of extra microphones. Learning to use an unfamiliar communication medium proved to be uncomplicated for the participating physicians.

  2. A VBA Desktop Database for Proposal Processing at National Optical Astronomy Observatories

    Science.gov (United States)

    Brown, Christa L.

    National Optical Astronomy Observatories (NOAO) has developed a relational Microsoft Windows desktop database using Microsoft Access and the Microsoft Office programming language, Visual Basic for Applications (VBA). The database is used to track data relating to observing proposals from original receipt through the review process, scheduling, observing, and final statistical reporting. The database has automated proposal processing and distribution of information. It allows NOAO to collect and archive data so as to query and analyze information about our science programs in new ways.

  3. The use of the webcam for teaching a foreign language in a desktop videoconferencing environment

    OpenAIRE

    Develotte, Christine; Guichon, Nicolas; Vincent, Caroline

    2010-01-01

    International audience; This paper explores how language teachers learn to teach with a synchronous multimodal setup (Skype), and it focuses on their use of the webcam during the pedagogical interaction. First, we analyze the ways that French graduate students learning to teach online use the multimodal resources available in a desktop videoconferencing (DVC) environment to monitor pedagogical interactions with intermediate level learners of French in a North-American university. Then, we exa...

  4. In and out the frame: teacher gestures during desktop videoconferencing interactions

    OpenAIRE

    Wigham, Ciara R.; Guichon, Nicolas

    2014-01-01

    This presentation will focus on the production of gestures by teacher trainees when they are interacting online with distant language learners during a desktop videoconferencing interaction. Previous research has provided a mixed picture of the use of the webcam in pedagogical situations: while it is seen as a useful medium to provide complementary information in communicative breakdown (Buckett, Stringer and Datta, 1999), the limited access to visual cues provided by the webcam is felt as li...

  5. Reducing the Digital Divide among Children Who Received Desktop or Hybrid Computers for the Home

    Directory of Open Access Journals (Sweden)

    Gila Cohen Zilka

    2016-06-01

    Full Text Available Researchers and policy makers have been exploring ways to reduce the digital divide. Parameters commonly used to examine the digital divide worldwide, as well as in this study, are: (a the digital divide in the accessibility and mobility of the ICT infrastructure and of the content infrastructure (e.g., sites used in school; and (b the digital divide in literacy skills. In the present study we examined the degree of effectiveness of receiving a desktop or hybrid computer for the home in reducing the digital divide among children of low socio-economic status aged 8-12 from various localities across Israel. The sample consisted of 1,248 respondents assessed in two measurements. As part of the mixed-method study, 128 children were also interviewed. Findings indicate that after the children received desktop or hybrid computers, changes occurred in their frequency of access, mobility, and computer literacy. Differences were found between the groups: hybrid computers reduce disparities and promote work with the computer and surfing the Internet more than do desktop computers. Narrowing the digital divide for this age group has many implications for the acquisition of skills and study habits, and consequently, for the realization of individual potential. The children spoke about self improvement as a result of exposure to the digital environment, about a sense of empowerment and of improvement in their advantage in the social fabric. Many children expressed a desire to continue their education and expand their knowledge of computer applications, the use of software, of games, and more. Therefore, if there is no computer in the home and it is necessary to decide between a desktop and a hybrid computer, a hybrid computer is preferable.

  6. Network Computer Technology. Phase I: Viability and Promise within NASA's Desktop Computing Environment

    Science.gov (United States)

    Paluzzi, Peter; Miller, Rosalind; Kurihara, West; Eskey, Megan

    1998-01-01

    Over the past several months, major industry vendors have made a business case for the network computer as a win-win solution toward lowering total cost of ownership. This report provides results from Phase I of the Ames Research Center network computer evaluation project. It identifies factors to be considered for determining cost of ownership; further, it examines where, when, and how network computer technology might fit in NASA's desktop computing architecture.

  7. Fab the coming revolution on your desktop : from personal computers to personal fabrication

    CERN Document Server

    Gershenfeld, Neil

    2005-01-01

    What if you could someday put the manufacturing power of an automobile plant on your desktop? According to Neil Gershenfeld, the renowned MIT scientist and inventor, the next big thing is personal fabrication-the ability to design and produce your own products, in your own home, with a machine that combines consumer electronics and industrial tools. Personal fabricators are about to revolutionize the world just as personal computers did a generation ago, and Fab shows us how.

  8. EKSPLORASI AKTINOMISET SEBAGAI PENGHASIL ANTIBIOTIKA DARI TANAH MANGROVE Sonneratia caseolaris DI TANJUNG API API

    Directory of Open Access Journals (Sweden)

    Awalul Fatiqin

    2015-08-01

    Full Text Available Actinomycetes are soil organisms that have traits that are common to bacteria and fungi but also have quite different characteristics that limit into one group which is distinctly different. Study aimed to explore the mangrove actinomycetes from soil and tested the antibacterial potency. Soil samples taken from the mangrove land at Tanjung Api-api mangrove species Sonneratia caseolaris. Activity test antibacterial using a method modified disk a test bacterium Escherichia coli. Identification isolates of actinomycetes by observing the character of macroscopic colonies, microscopic conidia. The results showed that the obtained three different actinomycetes isolates, 1 isolate has the most potential ability to inhibit bacterial growth test with an average value of 1:13 cm in inhibiting the bacteria Escherichia coli.

  9. C__Users_HP Pro 2000_Desktop_NUAMA.xps

    African Journals Online (AJOL)

    HP Pro 2000

    rang au sein des cultures vivrières. Sa place se justifie non seulement par les conditions climatiques et édaphiques favorables, mais aussi par un fait culturel : elle constitue l'aliment de base de plusieurs groupes ethniques et entre dans plusieurs rituels traditionnels (fêtes d'ignames, cérémonies d'intronisation, etc.). De.

  10. C:\\Users\\AISA\\Desktop\\J. AVAKOUDJO.xps

    African Journals Online (AJOL)

    AISA

    du sol, la granulométrie, le taux de carbone organique du sol, l'azote total, les phosphores assimilable et total, la somme des bases échangeables ... la couverture végétale, la valeur d'agrément. (pression à l'emploi) et de gestion des terres ; ...... Changes to Physicochemical Properties of Ultisols Distributed on Calcareous.

  11. Efficient Redundancy Techniques in Cloud and Desktop Grid Systems using MAP/G/c-type Queues

    Science.gov (United States)

    Chakravarthy, Srinivas R.; Rumyantsev, Alexander

    2018-03-01

    Cloud computing is continuing to prove its flexibility and versatility in helping industries and businesses as well as academia as a way of providing needed computing capacity. As an important alternative to cloud computing, desktop grids allow to utilize the idle computer resources of an enterprise/community by means of distributed computing system, providing a more secure and controllable environment with lower operational expenses. Further, both cloud computing and desktop grids are meant to optimize limited resources and at the same time to decrease the expected latency for users. The crucial parameter for optimization both in cloud computing and in desktop grids is the level of redundancy (replication) for service requests/workunits. In this paper we study the optimal replication policies by considering three variations of Fork-Join systems in the context of a multi-server queueing system with a versatile point process for the arrivals. For services we consider phase type distributions as well as shifted exponential and Weibull. We use both analytical and simulation approach in our analysis and report some interesting qualitative results.

  12. Investigation Methodology of a Virtual Desktop Infrastructure for IoT

    Directory of Open Access Journals (Sweden)

    Doowon Jeong

    2015-01-01

    Full Text Available Cloud computing for IoT (Internet of Things has exhibited the greatest growth in the IT market in the recent past and this trend is expected to continue. Many companies are adopting a virtual desktop infrastructure (VDI for private cloud computing to reduce costs and enhance the efficiency of their servers. As a VDI is widely used, threats of cyber terror and invasion are also increasing. To minimize the damage, response procedure for cyber intrusion on a VDI should be systematized. Therefore, we propose an investigation methodology for VDI solutions in this paper. Here we focus on a virtual desktop infrastructure and introduce various desktop virtualization solutions that are widely used, such as VMware, Citrix, and Microsoft. In addition, we verify the integrity of the data acquired in order that the result of our proposed methodology is acceptable as evidence in a court of law. During the experiment, we observed an error: one of the commonly used digital forensic tools failed to mount a dynamically allocated virtual disk properly.

  13. In vitro evaluation of the effects of some plant essential oils on Ascosphaera apis, the causative agent of Chalkbrood disease

    Directory of Open Access Journals (Sweden)

    Mohammad Javed Ansari

    2017-07-01

    Full Text Available Ascosphaera apis is one of the major fungal pathogens of honey bee broods and the causative agent of Chalkbrood disease. The factors responsible for the pathogenesis of Chalkbrood disease are still not fully understood, and the increasing resistance of A. apis to commonly used antifungal agents necessitates a search for new agents to control this disease. The in vitro antifungal activities of 27 plant essential oils against two isolates of A. apis (Aksu-4 and Aksu-9 were evaluated. Out of the 27 plant essential oils tested, 21 were found to be effective in killing both isolates of A. apis. Based on their minimum fungicidal concentration (MFC values, the effective oils were grouped into three categories: highly effective, moderately effective and minimally effective. Mountain pepper oil, Kala Bhangra oil, spearmint oil, babuna oil, betel leaf oil, carrot seed oil, cumin seed oil and clove bud oil were highly effective, with MBC values between 50.0 μg/mL and 600.0 μg/mL. Mountain pepper was the most effective essential oil, with an MBC value of 50.0 μg/mL. Citral and caryophyllene containing oils were the most effective with MIC 50 ppm. The essential oils tested exhibited significant antimicrobial activities against both strains of A. apis, and they may contain compounds that could play an important role in the treatment or prevention of Chalkbrood disease of honeybee.

  14. Compositional mining of multiple object API protocols through state abstraction.

    Science.gov (United States)

    Dai, Ziying; Mao, Xiaoguang; Lei, Yan; Qi, Yuhua; Wang, Rui; Gu, Bin

    2013-01-01

    API protocols specify correct sequences of method invocations. Despite their usefulness, API protocols are often unavailable in practice because writing them is cumbersome and error prone. Multiple object API protocols are more expressive than single object API protocols. However, the huge number of objects of typical object-oriented programs poses a major challenge to the automatic mining of multiple object API protocols: besides maintaining scalability, it is important to capture various object interactions. Current approaches utilize various heuristics to focus on small sets of methods. In this paper, we present a general, scalable, multiple object API protocols mining approach that can capture all object interactions. Our approach uses abstract field values to label object states during the mining process. We first mine single object typestates as finite state automata whose transitions are annotated with states of interacting objects before and after the execution of the corresponding method and then construct multiple object API protocols by composing these annotated single object typestates. We implement our approach for Java and evaluate it through a series of experiments.

  15. Compositional Mining of Multiple Object API Protocols through State Abstraction

    Directory of Open Access Journals (Sweden)

    Ziying Dai

    2013-01-01

    Full Text Available API protocols specify correct sequences of method invocations. Despite their usefulness, API protocols are often unavailable in practice because writing them is cumbersome and error prone. Multiple object API protocols are more expressive than single object API protocols. However, the huge number of objects of typical object-oriented programs poses a major challenge to the automatic mining of multiple object API protocols: besides maintaining scalability, it is important to capture various object interactions. Current approaches utilize various heuristics to focus on small sets of methods. In this paper, we present a general, scalable, multiple object API protocols mining approach that can capture all object interactions. Our approach uses abstract field values to label object states during the mining process. We first mine single object typestates as finite state automata whose transitions are annotated with states of interacting objects before and after the execution of the corresponding method and then construct multiple object API protocols by composing these annotated single object typestates. We implement our approach for Java and evaluate it through a series of experiments.

  16. C:\\Users\\AISA\\Desktop\\D. A. MOU

    African Journals Online (AJOL)

    AISA

    adultes de cet insecte à base de fleurs de trois espèces végétales, à savoir Balanites aegyptiaca, Neocarya macrophylla, Acacia seyal et ... les résultats révèlent que plus la taille de la graine est importante plus le nombre d'œufs déposés est élevé. Le taux de survie ..... Reproduction et développement de B. atrolineatus Pic ...

  17. C:\\Users\\AISA\\Desktop\\KALLEL SADREDDINE.xps

    African Journals Online (AJOL)

    AISA

    dans des récipients en plastique avec un couvercle de 12 cm de hauteur et présentant une base circulaire de 11cm de diamètre. Les sols sont par la suite humidifiés et déposés sur un papier filtre de 13 cm de diamètre préalablement humidifié et recevant soit des œufs de criquets soit des chenilles de Galleria mellonella.

  18. C:\\Users\\AISA\\Desktop\\F-G. GACHA.xps

    African Journals Online (AJOL)

    AISA

    la Société pour le développement des productions animales (SODEPRA) obéit également à cette ... Cette option tient compte de l'histoire et de la culture sur la base desquelles les acteurs construisent leurs ..... stratégiques du développement agricole ivoirien. Abidjan, 11-12 Mars CIRES,. 1982, 15p. Benoît M. 1979.

  19. A framework for API solubility modelling

    DEFF Research Database (Denmark)

    Conte, Elisa; Gani, Rafiqul; Crafts, Peter

    The solubility of solid organic compounds in water and organic solvents is a fundamental thermodynamic property for many purposes such as product-process design and optimization, for the chemical and pharmaceutical industry. Experimental literature solubility data are usually scarce and temperature......-dependent measurements are expensive in terms of time and resources. The few available data are badly organized and difficult to use for fast solubility calculations and solvent screening. Available models often require time consuming and complex implementation together with a good user expertise for their efficient use....... In addition, most of the models are not predictive and requires experimental data for the calculation of the needed parameters. This work aims at developing an efficient framework for the solubility modelling of Active Pharmaceutical Ingredients (API) in water and organic solvents. With this framework...

  20. No effect of ambient odor on the affective appraisal of a desktop virtual environment with signs of disorder.

    Directory of Open Access Journals (Sweden)

    Alexander Toet

    Full Text Available Desktop virtual environments (VEs are increasingly deployed to study the effects of environmental qualities and interventions on human behavior and safety related concerns in built environments. For these applications it is essential that users appraise the affective qualities of the VE similar to those of its real world counterpart. Previous studies have shown that factors like simulated lighting, sound and dynamic elements all contribute to the affective appraisal of a desktop VE. Since ambient odor is known to affect the affective appraisal of real environments, and has been shown to increase the sense of presence in immersive VEs, it may also be an effective tool to tune the affective appraisal of desktop VEs. This study investigated if exposure to ambient odor can modulate the affective appraisal of a desktop VE with signs of public disorder.Participants explored a desktop VE representing a suburban neighborhood with signs of public disorder (neglect, vandalism and crime, while being exposed to either room air or subliminal levels of unpleasant (tar or pleasant (cut grass ambient odor. Whenever they encountered signs of disorder they reported their safety related concerns and associated affective feelings.Signs of crime in the desktop VE were associated with negative affective feelings and concerns for personal safety and personal property. However, there was no significant difference between reported safety related concerns and affective connotations in the control (no-odor and in each of the two ambient odor conditions.Ambient odor did not affect safety related concerns and affective connotations associated with signs of disorder in the desktop VE. Thus, semantic congruency between ambient odor and a desktop VE may not be sufficient to influence its affective appraisal, and a more realistic simulation in which simulated objects appear to emit scents may be required to achieve this goal.

  1. No effect of ambient odor on the affective appraisal of a desktop virtual environment with signs of disorder.

    Science.gov (United States)

    Toet, Alexander; van Schaik, Martin; Theunissen, Nicolet C M

    2013-01-01

    Desktop virtual environments (VEs) are increasingly deployed to study the effects of environmental qualities and interventions on human behavior and safety related concerns in built environments. For these applications it is essential that users appraise the affective qualities of the VE similar to those of its real world counterpart. Previous studies have shown that factors like simulated lighting, sound and dynamic elements all contribute to the affective appraisal of a desktop VE. Since ambient odor is known to affect the affective appraisal of real environments, and has been shown to increase the sense of presence in immersive VEs, it may also be an effective tool to tune the affective appraisal of desktop VEs. This study investigated if exposure to ambient odor can modulate the affective appraisal of a desktop VE with signs of public disorder. Participants explored a desktop VE representing a suburban neighborhood with signs of public disorder (neglect, vandalism and crime), while being exposed to either room air or subliminal levels of unpleasant (tar) or pleasant (cut grass) ambient odor. Whenever they encountered signs of disorder they reported their safety related concerns and associated affective feelings. Signs of crime in the desktop VE were associated with negative affective feelings and concerns for personal safety and personal property. However, there was no significant difference between reported safety related concerns and affective connotations in the control (no-odor) and in each of the two ambient odor conditions. Ambient odor did not affect safety related concerns and affective connotations associated with signs of disorder in the desktop VE. Thus, semantic congruency between ambient odor and a desktop VE may not be sufficient to influence its affective appraisal, and a more realistic simulation in which simulated objects appear to emit scents may be required to achieve this goal.

  2. Outline of the Desktop Severe Accident Graphic Simulator Module for OPR-1000

    Energy Technology Data Exchange (ETDEWEB)

    Park, S. Y.; Ahn, K. I. [KAERI, Daejeon (Korea, Republic of)

    2015-05-15

    This paper introduce the desktop severe accident graphic simulator module (VMAAP) which is a window-based severe accident simulator using MAAP as its engine. The VMAAP is one of the submodules in SAMEX system (Severe Accident Management Support Expert System) which is a decision support system for use in a severe accident management following an incident at a nuclear power plant. The SAMEX system consists of four major modules as sub-systems: (a) Severe accident risk data base module (SARDB): stores the data of integrated severe accident analysis code results like MAAP and MELCOR for hundreds of high frequency scenarios for the reference plant; (b) Risk-informed severe accident risk data base management module (RI-SARD): provides a platform to identify the initiating event, determine plant status and equipment availability, diagnoses the status of the reactor core, reactor vessel and containment building, and predicts the plant behaviors; (c) Severe accident management simulator module (VMAAP): runs the MAAP4 code with user friendly graphic interface for input deck and output display; (d) On-line severe accident management guidance module (On-line SAMG); provides available accident management strategies with an electronic format. The role of VMAAP in SAMEX can be described as followings. SARDB contains the most of high frequency scenarios based on a level 2 probabilistic safety analysis. Therefore, there is good chance that a real accident sequence is similar to one of the data base cases. In such a case, RI-SARD can predict an accident progression by a scenario-base or symptom-base search depends on the available plant parameter information. Nevertheless, there still may be deviations or variations between the actual scenario and the data base scenario. The deviations can be decreased by using a real-time graphic accident simulator, VMAAP.. VMAAP is a MAAP4-based severe accident simulation model for OPR-1000 plant. It can simulate spectrum of physical processes

  3. Outline of the Desktop Severe Accident Graphic Simulator Module for OPR-1000

    International Nuclear Information System (INIS)

    Park, S. Y.; Ahn, K. I.

    2015-01-01

    This paper introduce the desktop severe accident graphic simulator module (VMAAP) which is a window-based severe accident simulator using MAAP as its engine. The VMAAP is one of the submodules in SAMEX system (Severe Accident Management Support Expert System) which is a decision support system for use in a severe accident management following an incident at a nuclear power plant. The SAMEX system consists of four major modules as sub-systems: (a) Severe accident risk data base module (SARDB): stores the data of integrated severe accident analysis code results like MAAP and MELCOR for hundreds of high frequency scenarios for the reference plant; (b) Risk-informed severe accident risk data base management module (RI-SARD): provides a platform to identify the initiating event, determine plant status and equipment availability, diagnoses the status of the reactor core, reactor vessel and containment building, and predicts the plant behaviors; (c) Severe accident management simulator module (VMAAP): runs the MAAP4 code with user friendly graphic interface for input deck and output display; (d) On-line severe accident management guidance module (On-line SAMG); provides available accident management strategies with an electronic format. The role of VMAAP in SAMEX can be described as followings. SARDB contains the most of high frequency scenarios based on a level 2 probabilistic safety analysis. Therefore, there is good chance that a real accident sequence is similar to one of the data base cases. In such a case, RI-SARD can predict an accident progression by a scenario-base or symptom-base search depends on the available plant parameter information. Nevertheless, there still may be deviations or variations between the actual scenario and the data base scenario. The deviations can be decreased by using a real-time graphic accident simulator, VMAAP.. VMAAP is a MAAP4-based severe accident simulation model for OPR-1000 plant. It can simulate spectrum of physical processes

  4. Data Management API within the GridRPC

    OpenAIRE

    Caniou, Yves; Caron, Eddy; Le Mahec, Gaël; Nakada, Hidemoto

    2011-01-01

    Copyright (c) Open Grid Forum (2006-2011). Some Rights Reserved. Distribution is unlimited.; standardization; This document follows the document produced by the GridRPC-WG on GridRPC Model and API for End-User applications. This new document aims to complete the GridRPC API with Data Management mechanisms and API.This document is not intended to provide features and capabilities for building data management middle- ware. Its goal is to complete the GridRPC set of functions and definitions to ...

  5. Open-Source Neural Machine Translation API Server

    Directory of Open Access Journals (Sweden)

    Tars Sander

    2017-10-01

    Full Text Available We introduce an open-source implementation of a machine translation API server. The aim of this software package is to enable anyone to run their own multi-engine translation server with neural machine translation engines, supporting an open API for client applications. Besides the hub with the implementation of the client API and the translation service providers running in the background we also describe an open-source demo web application that uses our software package and implements an online translation tool that supports collecting translation quality comparisons from users.

  6. JUPITER: Joint Universal Parameter IdenTification and Evaluation of Reliability - An Application Programming Interface (API) for Model Analysis

    Science.gov (United States)

    Banta, Edward R.; Poeter, Eileen P.; Doherty, John E.; Hill, Mary C.

    2006-01-01

    predictions.Use calibration methods to modify parameter values and other aspects of the model.Compare predictions to regulatory limits.Quantify the uncertainty of predictions based on the results of one or many simulations using inferential or Monte Carlo methods.Determine how to manage the system to achieve stated objectives.The capabilities provided by the JUPITER API include, for example, communication with process models, parallel computations, compressed storage of matrices, and flexible input capabilities. The input capabilities use input blocks suitable for lists or arrays of data. The input blocks needed for one application can be included within one data file or distributed among many files. Data exchange between different JUPITER API applications or between applications and other programs is supported by data-exchange files.The JUPITER API has already been used to construct a number of applications. Three simple example applications are presented in this report. More complicated applications include the universal inverse code UCODE_2005 (Poeter et al., 2005), the multi-model analysis MMA (Eileen P. Poeter, Mary C. Hill, E.R. Banta, S.W. Mehl, and Steen Christensen, written commun., 2006), and a code named OPR_PPR (Matthew J. Tonkin, Claire R. Tiedeman, Mary C. Hill, and D. Matthew Ely, written communication, 2006).This report describes a set of underlying organizational concepts and complete specifics about the JUPITER API. While understanding the organizational concept presented is useful to understanding the modules, other organizational concepts can be used in applications constructed using the JUPITER API.

  7. Rapid identification of thermophilic Naegleria, including Naegleria fowleri using API ZYM system.

    OpenAIRE

    Kilvington, S; White, D G

    1985-01-01

    The suitability of the API ZYM system for identifying thermophilic Naegleria species, based on enzyme presence and activity, was investigated. Replicate testing on strains of N fowleri, N lovaniensis, and N australiensis cultured in a monoxenic and an axenic medium showed that the system could provide a rapid and reproducible means of identifying the species soon after primary isolation. No single enzyme was found specific for any one species, but considerable differences were found in the pa...

  8. Distinguishing feral and managed honeybees (Apis mellifera) using stable carbon isotopes

    OpenAIRE

    Anderson, Lucy; Dynes, Travis; Berry, Jennifer; Delaplane, Keith; McCormick, Lydia; Brosi, Berry

    2014-01-01

    International audience; The ability to distinguish feral and managed honeybees (Apis mellifera) has applications in studies of population genetics, parasite transmission, pollination, interspecific interactions, and bee breeding. We evaluated a diagnostic test based on theoretical differences in stable carbon isotope ratios generated by supplemental feeding. We evaluated (1) if carbon isotope ratios can distinguish feral and managed honeybees and (2) the temporal persistence of the signal aft...

  9. Rapid identification of group D streptococci with the API 20S system.

    OpenAIRE

    Jorgensen, J H; Crawford, S A; Alexander, G A

    1983-01-01

    The API 20S system (Analytab Products) was evaluated as a means of identifying 209 isolates of Lancefield group D streptococci to the species level. Results were compared with those from a conventional tube biochemical identification system and from serological grouping. Use of the latest 20S computerized data base allowed species identification of 97% (203 of 209) of test isolates after a 4-h incubation period and 99% (208 of 209) of test isolates if supplemental overnight biochemical tests ...

  10. Desktop Severe Accident Graphic Simulator Module for CANDU6 : PSAIS

    Energy Technology Data Exchange (ETDEWEB)

    Park, S. Y.; Song, Y. M. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    The ISAAC ((Integrated Severe Accident Analysis Code for CANDU Plant) code is a system level computer code capable of performing integral analyses of potential severe accident progressions in nuclear power plants, whose main purpose is to support a Level 2 probabilistic safety assessment or severe accident management strategy developments. The code has the capability to predict a severe accident progression by modeling the CANDU6- specific systems and the expected physical phenomena based on the current understanding of the unique accident progressions. The code models the sequence of accident progressions from a core heatup, pressure tube/calandria tube rupture after an uncovery from inside and outside, a relocation of the damaged fuel to the bottom of the calandria, debris behavior in the calandria, corium quenching after a debris relocation from the calandria to the calandria vault and an erosion of the calandria vault concrete floor, a hydrogen burn, and a reactor building failure. Along with the thermal hydraulics, the fission product behavior is also considered in the primary system as well as in the reactor building.

  11. Application of Google Maps API service for creating web map of information retrieved from CORINE land cover databases

    Directory of Open Access Journals (Sweden)

    Kilibarda Milan

    2010-01-01

    Full Text Available Today, Google Maps API application based on Ajax technology as standard web service; facilitate users with publication interactive web maps, thus opening new possibilities in relation to the classical analogue maps. CORINE land cover databases are recognized as the fundamental reference data sets for numerious spatial analysis. The theoretical and applicable aspects of Google Maps API cartographic service are considered on the case of creating web map of change in urban areas in Belgrade and surround from 2000. to 2006. year, obtained from CORINE databases.

  12. Molecular characterization of Api g 2, a novel allergenic member of the lipid-transfer protein 1 family from celery stalks.

    Science.gov (United States)

    Gadermaier, Gabriele; Egger, Matthias; Girbl, Tamara; Erler, Anja; Harrer, Andrea; Vejvar, Eva; Liso, Marina; Richter, Klaus; Zuidmeer, Laurian; Mari, Adriano; Ferreira, Fatima

    2011-04-01

    Celery represents a relevant cross-reactive food allergen source in the adult population. As the currently known allergens are not typical elicitors of severe symptoms, we aimed to identify and characterize a non-specific lipid transfer protein (nsLTP). MS and cDNA cloning were applied to obtain the full-length sequence of a novel allergenic nsLTP from celery stalks. The purified natural molecule consisted of a single isoallergen designated as Api g 2.0101, which was recombinantly produced in Escherichia coli Rosetta-gami. The natural and recombinant molecules displayed equivalent physicochemical and immunological properties. Circular dichroism revealed a typical α-helical fold and high thermal stability. Moreover, Api g 2 was highly resistant to simulated gastrointestinal digestion. As assessed by ELISA, thermal denaturation did not affect the IgE binding of Api g 2. Natural and recombinant Api g 2 showed similar allergenic activity in mediator release assays. Api g 2-specific IgE antibodies cross-reacted with peach and mugwort pollen nsLTPs. Based on our results, it can be anticipated that inclusion of recombinant Api g 2 in the current panel of allergens for molecule-based diagnosis will facilitate the evaluation of the clinical relevance of nsLTP sensitization in celery allergy and help clinicians in the management of food allergic patients. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Safe "cloudification" of large images through picker APIs.

    Science.gov (United States)

    Bremer, Erich; Kurc, Tahsin; Gao, Yi; Saltz, Joel; Almeida, Jonas S

    2016-01-01

    The "Box model" allows users with no particular training in informatics, or access to specialized infrastructure, operate generic cloud computing resources through a temporary URI dereferencing mechanism known as "drop-file-picker API" ("picker API" for sort). This application programming interface (API) was popularized in the web app development community by DropBox, and is now a consumer-facing feature of all major cloud computing platforms such as Box.com, Google Drive and Amazon S3. This reports describes a prototype web service application that uses picker APIs to expose a new, "cloudified", API tailored for image analysis, without compromising the private governance of the data exposed. In order to better understand this cross-platform cloud computing landscape, we first measured the time for both transfer and traversing of large image files generated by whole slide imaging (WSI) in Digital Pathology. The verification that there is extensive interconnectivity between cloud resources let to the development of a prototype software application that exposes an image-traversing REST API to image files stored in any of the consumer-facing "boxes". In summary, an image file can be upload/synchronized into a any cloud resource with a file picker API and the prototype service described here will expose an HTTP REST API that remains within the safety of the user's own governance. The open source prototype is publicly available at sbu-bmi.github.io/imagebox. Availability The accompanying prototype application is made publicly available, fully functional, with open source, at http://sbu-bmi.github.io/imagebox://sbu-bmi.github.io/imagebox. An illustrative webcasted use of this Web App is included with the project codebase at https://github.com/SBU-BMI/imageboxs://github.com/SBU-BMI/imagebox.

  14. DIGITAL TRANSFORMATION : HOW APIS DRIVE BUSINESS MODEL CHANGE AND INNOVATION

    OpenAIRE

    Hellbe, Simon; Leung, Peter

    2015-01-01

    Over the years, information technology has created opportunities to improve and extend businesses and to start conducting business in new ways. With the evolution of IT, all businesses and industries are becoming increasingly digitized. This process, or coevolution, of IT and business coming together is called digital transformation. One of the recent trends in this digital transformation is the use of application programmable interfaces (APIs). APIs are standardized digital communication int...

  15. Open chemistry: RESTful web APIs, JSON, NWChem and the modern web application.

    Science.gov (United States)

    Hanwell, Marcus D; de Jong, Wibe A; Harris, Christopher J

    2017-10-30

    An end-to-end platform for chemical science research has been developed that integrates data from computational and experimental approaches through a modern web-based interface. The platform offers an interactive visualization and analytics environment that functions well on mobile, laptop and desktop devices. It offers pragmatic solutions to ensure that large and complex data sets are more accessible. Existing desktop applications/frameworks were extended to integrate with high-performance computing resources, and offer command-line tools to automate interaction-connecting distributed teams to this software platform on their own terms. The platform was developed openly, and all source code hosted on the GitHub platform with automated deployment possible using Ansible coupled with standard Ubuntu-based machine images deployed to cloud machines. The platform is designed to enable teams to reap the benefits of the connected web-going beyond what conventional search and analytics platforms offer in this area. It also has the goal of offering federated instances, that can be customized to the sites/research performed. Data gets stored using JSON, extending upon previous approaches using XML, building structures that support computational chemistry calculations. These structures were developed to make it easy to process data across different languages, and send data to a JavaScript-based web client.

  16. Development, implementation, and analysis of desktop-scale model industrial equipment and a critical thinking rubric for use in chemical engineering education

    Science.gov (United States)

    Golter, Paul B.

    In order to address some of the challenges facing engineering education, namely the demand that students be better prepared to practice professional as well as technical skills, we have developed an intervention consisting of equipment, assessments and a novel pedagogy. The equipment consists of desktop-scale replicas of common industrial equipment. These are implemented in the form of modular cartridges that can be interchanged in a base unit containing water, power and instrumentation. These Desktop Learning Modules (DLMs) are effective at providing a hands on experience in most classroom environments without requiring either water or power hook-ups. Furthermore, the DLMs respond quickly enough that multiple experiments by multiple groups can be run in a single one hour class. We refined an existing critical thinking rubric to be more specific to the realm of engineering problem solving. By altering our pedagogy to a project based environment using the critical thinking rubric as a primary grading tool, we are able to observe and measure the critical thinking skills of student groups. This rubric is corroborated with an industrial perspective and measures constructs that are important to the students' future careers.

  17. Beginning the 21st century with advanced Automatic Parts Identification (API)

    Science.gov (United States)

    Schramm, Fred; Roxby, Don

    1994-01-01

    Under the direction of the NASA George C. Marshall Space Flight Center, Huntsville, Alabama, the development and commercialization of an advanced Automated Parts Indentification (API) system is being undertaken by Rockwell International Corporation. The new API system is based on a variable sized, machine-readable, two-dimensioanl matrix symbol that can be applied directly onto most metallic and nonmetallic materials using safe, permanent marking methods. Its checkerboard-like structure is the most space efficient of all symbologies. This high data-density symbology can be applied to products of different material sizes and geometries using application-dependent, computer-driven marking devices. The high fidelity markings produced by these devices can then be captured using a specially designed camera linked to any IBM-compatible computer. Applications of compressed symbology technology will reduce costs and improve quality, productivity, and processes in a wide variety of federal and commercial applications.

  18. Genetic reincarnation of workers as queens in the Eastern honeybee Apis cerana.

    Science.gov (United States)

    Holmes, M J; Tan, K; Wang, Z; Oldroyd, B P; Beekman, M

    2015-01-01

    Thelytokous parthenogenesis, or the asexual production of female offspring, is rare in the animal kingdom, but relatively common in social Hymenoptera. However, in honeybees, it is only known to be ubiquitous in one subspecies of Apis mellifera, the Cape honeybee, A. mellifera capensis. Here we report the appearance of queen cells in two colonies of the Eastern honeybee Apis cerana that no longer contained a queen or queen-produced brood to rear queens from. A combination of microsatellite genotyping and the timing of the appearance of these individuals excluded the possibility that they had been laid by the original queen. Based on the genotypes of these individuals, thelytokous production by natal workers is the most parsimonious explanation for their existence. Thus, we present the first example of thelytoky in a honeybee outside A. mellifera. We discuss the evolutionary and ecological consequences of thelytoky in A. cerana, in particular the role thelytoky may play in the recent invasions by populations of this species.

  19. Rapid identification of group D streptococci with the API 20S system.

    Science.gov (United States)

    Jorgensen, J H; Crawford, S A; Alexander, G A

    1983-06-01

    The API 20S system (Analytab Products) was evaluated as a means of identifying 209 isolates of Lancefield group D streptococci to the species level. Results were compared with those from a conventional tube biochemical identification system and from serological grouping. Use of the latest 20S computerized data base allowed species identification of 97% (203 of 209) of test isolates after a 4-h incubation period and 99% (208 of 209) of test isolates if supplemental overnight biochemical tests were used to clarify the identity of five Streptococcus bovis-variant isolates. The API 20S system appears to be a convenient and accurate method for rapid, same-day species identification of group D streptococci.

  20. GIANT API: an application programming interface for functional genomics.

    Science.gov (United States)

    Roberts, Andrew M; Wong, Aaron K; Fisk, Ian; Troyanskaya, Olga G

    2016-07-08

    GIANT API provides biomedical researchers programmatic access to tissue-specific and global networks in humans and model organisms, and associated tools, which includes functional re-prioritization of existing genome-wide association study (GWAS) data. Using tissue-specific interaction networks, researchers are able to predict relationships between genes specific to a tissue or cell lineage, identify the changing roles of genes across tissues and uncover disease-gene associations. Additionally, GIANT API enables computational tools like NetWAS, which leverages tissue-specific networks for re-prioritization of GWAS results. The web services covered by the API include 144 tissue-specific functional gene networks in human, global functional networks for human and six common model organisms and the NetWAS method. GIANT API conforms to the REST architecture, which makes it stateless, cacheable and highly scalable. It can be used by a diverse range of clients including web browsers, command terminals, programming languages and standalone apps for data analysis and visualization. The API is freely available for use at http://giant-api.princeton.edu. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

  1. First detection of the larval chalkbrood disease pathogen Ascosphaera apis (Ascomycota: Eurotiomycetes: Ascosphaerales) in adult bumble bees.

    Science.gov (United States)

    Maxfield-Taylor, Sarah A; Mujic, Alija B; Rao, Sujaya

    2015-01-01

    Fungi in the genus Ascosphaera (Ascomycota: Eurotiomycetes: Ascosphaerales) cause chalkbrood disease in larvae of bees. Here, we report the first-ever detection of the fungus in adult bumble bees that were raised in captivity for studies on colony development. Wild queens of Bombus griseocollis, B. nevadensis and B. vosnesenskii were collected and maintained for establishment of nests. Queens that died during rearing or that did not lay eggs within one month of capture were dissected, and tissues were examined microscopically for the presence of pathogens. Filamentous fungi that were detected were plated on artificial media containing broad spectrum antibiotics for isolation and identification. Based on morphological characters, the fungus was identified as Ascosphaera apis (Maasen ex Claussen) Olive and Spiltoir, a species that has been reported earlier only from larvae of the European honey bee, Apis mellifera, the Asian honey bee, Apis cerana, and the carpenter bee Xylocopa californica arizonensis. The identity of the fungus was confirmed using molecular markers and phylogenetic analysis. Ascosphaera apis was detected in queens of all three bumble bee species examined. Of 150 queens dissected, 12 (8%) contained vegetative and reproductive stages of the fungus. Both fungal stages were also detected in two workers collected from colonies with Ascosphaera-infected B. nevadensis queens. In this study, wild bees could have been infected prior to capture for rearing, or, the A. apis infection could have originated via contaminated European honey bee pollen fed to the bumble bees in captivity. Thus, the discovery of A. apis in adult bumble bees in the current study has important implications for commercial production of bumble bee colonies and highlights potential risks to native bees via pathogen spillover from infected bees and infected pollen.

  2. First detection of the larval chalkbrood disease pathogen Ascosphaera apis (Ascomycota: Eurotiomycetes: Ascosphaerales in adult bumble bees.

    Directory of Open Access Journals (Sweden)

    Sarah A Maxfield-Taylor

    Full Text Available Fungi in the genus Ascosphaera (Ascomycota: Eurotiomycetes: Ascosphaerales cause chalkbrood disease in larvae of bees. Here, we report the first-ever detection of the fungus in adult bumble bees that were raised in captivity for studies on colony development. Wild queens of Bombus griseocollis, B. nevadensis and B. vosnesenskii were collected and maintained for establishment of nests. Queens that died during rearing or that did not lay eggs within one month of capture were dissected, and tissues were examined microscopically for the presence of pathogens. Filamentous fungi that were detected were plated on artificial media containing broad spectrum antibiotics for isolation and identification. Based on morphological characters, the fungus was identified as Ascosphaera apis (Maasen ex Claussen Olive and Spiltoir, a species that has been reported earlier only from larvae of the European honey bee, Apis mellifera, the Asian honey bee, Apis cerana, and the carpenter bee Xylocopa californica arizonensis. The identity of the fungus was confirmed using molecular markers and phylogenetic analysis. Ascosphaera apis was detected in queens of all three bumble bee species examined. Of 150 queens dissected, 12 (8% contained vegetative and reproductive stages of the fungus. Both fungal stages were also detected in two workers collected from colonies with Ascosphaera-infected B. nevadensis queens. In this study, wild bees could have been infected prior to capture for rearing, or, the A. apis infection could have originated via contaminated European honey bee pollen fed to the bumble bees in captivity. Thus, the discovery of A. apis in adult bumble bees in the current study has important implications for commercial production of bumble bee colonies and highlights potential risks to native bees via pathogen spillover from infected bees and infected pollen.

  3. DYNALIGHT DESKTOP

    DEFF Research Database (Denmark)

    Mærsk-Møller, Hans Martin; Kjær, Katrine Heinsvig; Ottosen, Carl-Otto

    2018-01-01

    approach uses weather forecasts and electricity prices to compute energy and cost-efficient supplemental light plans, which fulfils the production goals of the grower. The approach is supported by a set of newly developed planning software, which interfaces with a greenhouse climate computer. The planning...... for energy and cost-efficient climate control strategies that do not compromise product quality. In this paper, we present a novel approach addressing dynamic control of supplemental light in greenhouses aiming to decrease electricity costs and energy consumption without loss in plant productivity. Our...... resulted in large daily variation in the distribution and duration of light periods and daily light integrals (DLI). However, plant growth and flowering was mainly affected by differences in average DLI and marginally affected by the irregular light periods and a 25% reduction in electricity use and cost...

  4. DYNALIGHT DESKTOP

    DEFF Research Database (Denmark)

    Mærsk-Møller, Hans Martin; Kjær, Katrine Heinsvig; Ottosen, Carl-Otto

    2018-01-01

    approach uses weather forecasts and electricity prices to compute energy and cost-efficient supplemental light plans, which fulfils the production goals of the grower. The approach is supported by a set of newly developed planning software, which interfaces with a greenhouse climate computer. The planning...

  5. Magnetoreception system in honeybees (Apis mellifera.

    Directory of Open Access Journals (Sweden)

    Chin-Yuan Hsu

    Full Text Available Honeybees (Apis mellifera undergo iron biomineralization, providing the basis for magnetoreception. We showed earlier the presence of superparamagnetic magnetite in iron granules formed in honeybees, and subscribed to the notion that external magnetic fields may cause expansion or contraction of the superparamagnetic particles in an orientation-specific manner, relaying the signal via cytoskeleton (Hsu and Li 1994. In this study, we established a size-density purification procedure, with which quantitative amount of iron granules was obtained from honey bee trophocytes and characterized; the density of iron granules was determined to be 1.25 g/cm(3. While we confirmed the presence of superparamagnetic magnetite in the iron granules, we observed changes in the size of the magnetic granules in the trophycytes upon applying additional magnetic field to the cells. A concomitant release of calcium ion was observed by confocal microscope. This size fluctuation triggered the increase of intracellular Ca(+2 , which was inhibited by colchicines and latrunculin B, known to be blockers for microtubule and microfilament syntheses, respectively. The associated cytoskeleton may thus relay the magnetosignal, initiating a neural response. A model for the mechanism of magnetoreception in honeybees is proposed, which may be applicable to most, if not all, magnetotactic organisms.

  6. Honeybee (Apis mellifera ligustica) drone embryo proteomes.

    Science.gov (United States)

    Li, Jianke; Fang, Yu; Zhang, Lan; Begna, Desalegn

    2011-03-01

    Little attention has been paid to the drone honeybee (Apis mellifera ligustica) which is a haploid individual carrying only the set of alleles that it inherits from its mother. Molecular mechanisms underlying drone embryogenesis are poorly understood. This study evaluated protein expression profiles of drone embryogenesis at embryonic ages of 24, 48 and 72h. More than 100 reproducible proteins were analyzed by mass spectrometry on 2D electrophoresis gels. Sixty-two proteins were significantly changed at the selected three experimental age points. Expression of the metabolic energy requirement-related protein peaked at the embryonic age of 48h, whereas development and metabolizing amino acid-related proteins expressed optimally at 72h. Cytoskeleton, protein folding and antioxidant-related proteins were highly expressed at 48 and 72h. Protein networks of the identified proteins were constructed and protein expressions were validated at the transcription level. This first proteomic study of drone embryogenesis in the honeybee may provide geneticists an exact timetable and candidate protein outline for further manipulations of drone stem cells. Crown Copyright © 2010. Published by Elsevier Ltd. All rights reserved.

  7. The Apis mellifera Filamentous Virus Genome

    Directory of Open Access Journals (Sweden)

    Laurent Gauthier

    2015-07-01

    Full Text Available A complete reference genome of the Apis mellifera Filamentous virus (AmFV was determined using Illumina Hiseq sequencing. The AmFV genome is a double stranded DNA molecule of approximately 498,500 nucleotides with a GC content of 50.8%. It encompasses 247 non-overlapping open reading frames (ORFs, equally distributed on both strands, which cover 65% of the genome. While most of the ORFs lacked threshold sequence alignments to reference protein databases, twenty-eight were found to display significant homologies with proteins present in other large double stranded DNA viruses. Remarkably, 13 ORFs had strong similarity with typical baculovirus domains such as PIFs (per os infectivity factor genes: pif-1, pif-2, pif-3 and p74 and BRO (Baculovirus Repeated Open Reading Frame. The putative AmFV DNA polymerase is of type B, but is only distantly related to those of the baculoviruses. The ORFs encoding proteins involved in nucleotide metabolism had the highest percent identity to viral proteins in GenBank. Other notable features include the presence of several collagen-like, chitin-binding, kinesin and pacifastin domains. Due to the large size of the AmFV genome and the inconsistent affiliation with other large double stranded DNA virus families infecting invertebrates, AmFV may belong to a new virus family.

  8. Desktop system for accounting, audit, and research in A&E.

    Science.gov (United States)

    Taylor, C J; Brain, S G; Bull, F; Crosby, A C; Ferguson, D G

    1997-01-01

    The development of a database for audit, research, and accounting in accident and emergency (A&E) is described. The system uses a desktop computer, an optical scanner, sophisticated optical mark reader software, and workload management data. The system is highly flexible, easy to use, and at a cost of around 16,000 pounds affordable for larger departments wishing to move towards accounting. For smaller departments, it may be an alternative to full computerisation. Images Figure 1 Figure 2 Figure 3 Figure 5 Figure 6 PMID:9132200

  9. Development of an automated desktop procedure for defining macro-reaches for river longitudinal profiles

    CSIR Research Space (South Africa)

    Dollar, LH

    2006-07-01

    Full Text Available method Change points from WLRT method Crocodile 450 450 28 550 40 030 39 950 39 950 40 750λ 40 750λ 170 450 205 500 205 500 205 500 214 350 214 350 Olifants 1040 1040 5 890 24 090 23 390 23 390 26 540 26 540 47 690 132 340 161 290... cc. Cape Town. 140 pp. DOLLAR ESJ (2002) Desktop Geomorphological Analysis of IFR Sites 5, 6, 7, 8 and 9 for the Mhlathuze, Nseleni and Mfule Rivers, Northern KwaZulu-Natal. Unpublished Report for IWR Environmental. 19 pp. DOLLAR ESJ (2003) Macro...

  10. CLOUD-BASED VS DESKTOP-BASED PROPERTY MANAGEMENT SYSTEMS IN HOTEL

    OpenAIRE

    Mustafa GULMEZ; Edina AJANOVIC; Ismail KARAYUN

    2015-01-01

    Even though keeping up with the modern developments in IT sector is crucial for the success and competitiveness of a hotel, it is usually very hard for new technologies to be accepted and implemented. This is the case with the cloud technology for which the opinions between hoteliers are divided on those who think that it is just another fashion trend, unnecessary to be taken into consideration and those that believe that it helps in performing daily operations more easily, leaving space for ...

  11. blend4php: a PHP API for galaxy.

    Science.gov (United States)

    Wytko, Connor; Soto, Brian; Ficklin, Stephen P

    2017-01-01

    Galaxy is a popular framework for execution of complex analytical pipelines typically for large data sets, and is a commonly used for (but not limited to) genomic, genetic and related biological analysis. It provides a web front-end and integrates with high performance computing resources. Here we report the development of the blend4php library that wraps Galaxy's RESTful API into a PHP-based library. PHP-based web applications can use blend4php to automate execution, monitoring and management of a remote Galaxy server, including its users, workflows, jobs and more. The blend4php library was specifically developed for the integration of Galaxy with Tripal, the open-source toolkit for the creation of online genomic and genetic web sites. However, it was designed as an independent library for use by any application, and is freely available under version 3 of the GNU Lesser General Public License (LPGL v3.0) at https://github.com/galaxyproject/blend4phpDatabase URL: https://github.com/galaxyproject/blend4php. © The Author(s) 2017. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  12. Manipulating API and AOD data to distinguish transportation of aerosol at high altitude in Penang, Malaysia

    International Nuclear Information System (INIS)

    Tan, F; Lim, H S; Abdullah, K; Yoon, T L; Matjafri, M Z; Holben, B

    2014-01-01

    Air pollution index (API) is an index commonly used in Malaysia to determine the air quality level. It is a ground truth data measurement which is unable to unambiguously quantify air quality level at higher atmosphere. On the other hand, aerosol optical depth (AOD) from AERONET data obtained using sun photometer provides reading of the air quality for a column of atmosphere from ground surface. We first determine the quantitative correlation between the API and AOD data collected in Penang, Malaysia, between January – September, 2012, using two independent methods, one based on regression analysis and the other interpolation. Our purpose is to establish a systematic numerical procedure to determine whether aerosol transported in high altitude from other location has occurred. Two independent methods for establishing the quantitative relationship between the API and AOD data were used as a way to facilitate the verification of our approach. In our method, data from southwest monsoon period (August to September) were used as ''calibration dataset'' to establish the quantitative correlation between the AOD and API data. The established calibrated coefficients is then used to predict the AOD of other months, which are then compared against the data actually measured. Discrepancy between the predicted and measured AOD data can then be interpreted as an indication of whether the atmosphere at high altitude is polluted by aerosol transported from other location. If the predicted AOD is much larger than that measured, back trajectory analysis was applied to identify the aerosol transported source. This procedure is very helpful to investigate the aerosol transportation and distribution patterns during monsoon and non monsoon periods

  13. Early process development of API applied to poorly water-soluble TBID.

    Science.gov (United States)

    Meise, Marius; Niggemann, Matthias; Dunens, Alexandra; Schoenitz, Martin; Kuschnerow, Jan C; Kunick, Conrad; Scholl, Stephan

    2018-01-12

    Finding and optimising of synthesis processes for active pharmaceutical ingredients (API) is time consuming. In the finding phase, established methods for synthesis, purification and formulation are used to achieve a high purity API for biological studies. For promising API candidates, this is followed by pre-clinical and clinical studies requiring sufficient quantities of the active component. Ideally, these should be produced with a process representative for a later production process and suitable for scaling to production capacity. This work presents an overview of different approaches for process synthesis based on an existing lab protocol. This is demonstrated for the production of the model drug 4,5,6,7-tetrabromo-2-(1H-imidazol-2-yl) isoindolin-1,3-dione (TBID). Early batch synthesis and purification procedures typically suffer from low and fluctuating yields and purities due to poor process control. In a first step the literature synthesis and purification procedure was modified and optimized using solubility measurements, targeting easier and safer processing for consecutive studies. Copyright © 2018 Elsevier B.V. All rights reserved.

  14. PyPDB: a Python API for the Protein Data Bank.

    Science.gov (United States)

    Gilpin, William

    2016-01-01

    We have created a Python programming interface for the RCSB Protein Data Bank (PDB) that allows search and data retrieval for a wide range of result types, including BLAST and sequence motif queries. The API relies on the existing XML-based API and operates by creating custom XML requests from native Python types, allowing extensibility and straightforward modification. The package has the ability to perform many types of advanced search of the PDB that are otherwise only available through the PDB website. PyPDB is implemented exclusively in Python 3 using standard libraries for maximal compatibility. The most up-to-date version, including iPython notebooks containing usage tutorials, is available free-of-charge under an open-source MIT license via GitHub at https://github.com/williamgilpin/pypdb, and the full API reference is at http://williamgilpin.github.io/pypdb_docs/html/. The latest stable release is also available on PyPI. wgilpin@stanford.edu. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  15. Super-Atmospheric Pressure Ion Sources: Application and Coupling to API Mass Spectrometer

    Science.gov (United States)

    Chen, Lee Chuin; Rahman, Md. Matiur; Hiraoka, Kenzo

    2014-01-01

    Pressurizing the ionization source to gas pressure greater than atmospheric pressure is a new tactic aimed at further improving the performance of atmospheric pressure ionization (API) sources. In principle, all API sources, such as ESI, APCI and AP-MALDI, can be operated at pressure higher than 1 atm if suitable vacuum interface is available. The gas pressure in the ion source can have different role for different ionization. For example, in the case of ESI, stable electrospray could be sustained for high surface tension liquid (e.g., pure water) under super-atmospheric pressure, owing to the absence of electric discharge. Even for nanoESI, which is known to work well with aqueous solution, its stability and sensitivity were found to be enhanced, particularly in the negative mode when the ion source was pressurized. For the gas phase ionization like APCI, measurement of gaseous compound also showed an increase in ion intensity with the ion source pressure until an optimum pressure at around 4–5 atm. The enhancement was due to the increased collision frequency among reactant ion and analyte that promoted the ion/molecule reaction and a higher intake rate of gas to the mass spectrometer. Because the design of vacuum interface for API instrument is based on the upstream pressure of 1 atm, some coupling aspects need to be considered when connecting the high pressure ion source to the mass spectrometer. Several coupling strategies are discussed in this paper. PMID:26819896

  16. Super-Atmospheric Pressure Ion Sources: Application and Coupling to API Mass Spectrometer.

    Science.gov (United States)

    Chen, Lee Chuin; Rahman, Md Matiur; Hiraoka, Kenzo

    2014-01-01

    Pressurizing the ionization source to gas pressure greater than atmospheric pressure is a new tactic aimed at further improving the performance of atmospheric pressure ionization (API) sources. In principle, all API sources, such as ESI, APCI and AP-MALDI, can be operated at pressure higher than 1 atm if suitable vacuum interface is available. The gas pressure in the ion source can have different role for different ionization. For example, in the case of ESI, stable electrospray could be sustained for high surface tension liquid (e.g., pure water) under super-atmospheric pressure, owing to the absence of electric discharge. Even for nanoESI, which is known to work well with aqueous solution, its stability and sensitivity were found to be enhanced, particularly in the negative mode when the ion source was pressurized. For the gas phase ionization like APCI, measurement of gaseous compound also showed an increase in ion intensity with the ion source pressure until an optimum pressure at around 4-5 atm. The enhancement was due to the increased collision frequency among reactant ion and analyte that promoted the ion/molecule reaction and a higher intake rate of gas to the mass spectrometer. Because the design of vacuum interface for API instrument is based on the upstream pressure of 1 atm, some coupling aspects need to be considered when connecting the high pressure ion source to the mass spectrometer. Several coupling strategies are discussed in this paper.

  17. Inhibiting DNA methylation alters olfactory extinction but not acquisition learning in Apis cerana and Apis mellifera.

    Science.gov (United States)

    Gong, Zhiwen; Wang, Chao; Nieh, James C; Tan, Ken

    2016-07-01

    DNA methylation plays a key role in invertebrate acquisition and extinction memory. Honey bees have excellent olfactory learning, but the role of DNA methylation in memory formation has, to date, only been studied in Apis mellifera. We inhibited DNA methylation by inhibiting DNA methyltransferase (DNMT) with zebularine (zeb) and studied the resulting effects upon olfactory acquisition and extinction memory in two honey bee species, Apis cerana and A. mellifera. We used the proboscis extension reflex (PER) assay to measure memory. We provide the first demonstration that DNA methylation is also important in the olfactory extinction learning of A. cerana. DNMT did not reduce acquisition learning in either species. However, zeb bidirectionally and differentially altered extinction learning in both species. In particular, zeb provided 1h before acquisition learning improved extinction memory retention in A. mellifera, but reduced extinction memory retention in A. cerana. The reasons for these differences are unclear, but provide a basis for future studies to explore species-specific differences in the effects of methylation on memory formation. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. Quality control Lactobacillus strains for use with the API 50CH and API ZYM systems at 37 degrees C.

    Science.gov (United States)

    Charteris, W P; Kelly, P M; Morelli, L; Collins, J K

    2001-01-01

    The API 50CH and API ZYM systems fulfil an important role in the polyphasic taxonomic identification of lactobacilli. When the API 50CH fermentation profile of the quality control Lactobacillus casei var. alactosus (Lb. paracasei subsp. paracasei) strain NCFB 206 was determined at 37 degrees C, it was found to differ from that determined at 30 degrees C by BioMéreiux SA (Montalieu Vercieu, France) and the National Collection of Food Bacteria (Aberdeen, Scotland). In addition, the API 50CH fermentation and API ZYM profiles of Lb. casei strain ATCC 334T determined at 37 degrees C differed from those determined at 30 degrees C by Lee and Simard (1984). Strains NCFB 206 and ATCC 334T were thus assumed to exhibit temperature-dependent variation in fermentation profile, a phenomenon recently described by Nigatu et al. (2000). In contrast, Lb. rhamnosus strain ATCC 243T did not exhibit temperature-dependent variation in fermentation profile. Moreover, the fermentation profile obtained at 37 degrees C differed in only one respect (positive beta-gentiobiose utilisation) from that published by Collins et al. (1989). In addition, Lactobacillus strain GG produced a stable and reproducible API ZYM profile at 37 degrees C, although some variation in the level of enzyme activity was evident. Thus, strain NCFB 206 was replaced by strain ATCC 243T as the quality control strain of choice for use with the API 50CH fermentation system, and Lactobacillus strain GG adopted for use as a quality control strain with the API ZYM system for strain identification of lactobacilli at 37 degrees C. The API 50CH and API ZYM profiles of the commercially important Lactobacillus strains NCFB 1748, GG, KLD, F19, and ACA-DC 212.3 were determined at 37 degrees C after anaerobic growth in MRS broth. The fermentation and enzyme profiles of strain NCFB 1748 were almost identical to those of Lb. crispatus ATCC 33820T, those of strain GG were found to be more similar to those of Lb. rhamnosus strain 243T

  19. A quick guide to API 510 certified pressure vessel inspector syllabus example questions and worked answers

    CERN Document Server

    Matthews, Clifford

    2010-01-01

    The API Individual Certification Programs (ICPs) are well established worldwide in the oil, gas, and petroleum industries. This Quick Guide is unique in providing simple, accessible and well-structured guidance for anyone studying the API 510 Certified Pressure Vessel Inspector syllabus by summarizing and helping them through the syllabus and providing multiple example questions and worked answers.Technical standards are referenced from the API 'body of knowledge' for the examination, i.e. API 510 Pressure vessel inspection, alteration, rerating; API 572 Pressure vessel inspection; API

  20. Performance and function of a desktop viewer at Mayo Clinic Scottsdale.

    Science.gov (United States)

    Eversman, W G; Pavlicek, W; Zavalkovskiy, B; Erickson, B J

    2000-05-01

    A clinical viewing system was integrated with the Mayo Clinic Scottsdale picture archiving and communication system (PACS) for providing images and the report as part of the electronic medical record (EMR). Key attributes of the viewer include a single user log-on, an integrated patient centric EMR image access for all ordered examinations, prefetching of the most recent prior examination of the same modality, and the ability to provide comparison of current and past exams at the same time on the display. Other functions included preset windows, measurement tools, and multiformat display. Images for the prior 12 months are stored on the clinical server and are viewable in less than a second. Images available on the desktop include all computed radiography (CR), chest, magnetic resonance images (MRI), computed tomography (CT), ultrasound (U/S), nuclear, angiographic, gastrointestinal (GI) digital spots, and portable C-arm digital spots. Ad hoc queries of examinations from PACS are possible for those patients whose image may not be on the clinical server, but whose images reside on the PACS archive (10TB). Clinician satisfaction was reported to be high, especially for those staff heavily dependent on timely access to images, as well as those having heavy film usage. The desktop viewer is used for resident access to images. It is also useful for teaching conferences with large-screen projection without film. We report on the measurements of functionality, reliability, and speed of image display with this application.

  1. Fabrication of low cost soft tissue prostheses with the desktop 3D printer

    Science.gov (United States)

    He, Yong; Xue, Guang-Huai; Fu, Jian-Zhong

    2014-11-01

    Soft tissue prostheses such as artificial ear, eye and nose are widely used in the maxillofacial rehabilitation. In this report we demonstrate how to fabricate soft prostheses mold with a low cost desktop 3D printer. The fabrication method used is referred to as Scanning Printing Polishing Casting (SPPC). Firstly the anatomy is scanned with a 3D scanner, then a tissue casting mold is designed on computer and printed with a desktop 3D printer. Subsequently, a chemical polishing method is used to polish the casting mold by removing the staircase effect and acquiring a smooth surface. Finally, the last step is to cast medical grade silicone into the mold. After the silicone is cured, the fine soft prostheses can be removed from the mold. Utilizing the SPPC method, soft prostheses with smooth surface and complicated structure can be fabricated at a low cost. Accordingly, the total cost of fabricating ear prosthesis is about $30, which is much lower than the current soft prostheses fabrication methods.

  2. Fabrication of low cost soft tissue prostheses with the desktop 3D printer

    Science.gov (United States)

    He, Yong; Xue, Guang-huai; Fu, Jian-zhong

    2014-01-01

    Soft tissue prostheses such as artificial ear, eye and nose are widely used in the maxillofacial rehabilitation. In this report we demonstrate how to fabricate soft prostheses mold with a low cost desktop 3D printer. The fabrication method used is referred to as Scanning Printing Polishing Casting (SPPC). Firstly the anatomy is scanned with a 3D scanner, then a tissue casting mold is designed on computer and printed with a desktop 3D printer. Subsequently, a chemical polishing method is used to polish the casting mold by removing the staircase effect and acquiring a smooth surface. Finally, the last step is to cast medical grade silicone into the mold. After the silicone is cured, the fine soft prostheses can be removed from the mold. Utilizing the SPPC method, soft prostheses with smooth surface and complicated structure can be fabricated at a low cost. Accordingly, the total cost of fabricating ear prosthesis is about $30, which is much lower than the current soft prostheses fabrication methods. PMID:25427880

  3. Fabrication of low cost soft tissue prostheses with the desktop 3D printer.

    Science.gov (United States)

    He, Yong; Xue, Guang-huai; Fu, Jian-zhong

    2014-11-27

    Soft tissue prostheses such as artificial ear, eye and nose are widely used in the maxillofacial rehabilitation. In this report we demonstrate how to fabricate soft prostheses mold with a low cost desktop 3D printer. The fabrication method used is referred to as Scanning Printing Polishing Casting (SPPC). Firstly the anatomy is scanned with a 3D scanner, then a tissue casting mold is designed on computer and printed with a desktop 3D printer. Subsequently, a chemical polishing method is used to polish the casting mold by removing the staircase effect and acquiring a smooth surface. Finally, the last step is to cast medical grade silicone into the mold. After the silicone is cured, the fine soft prostheses can be removed from the mold. Utilizing the SPPC method, soft prostheses with smooth surface and complicated structure can be fabricated at a low cost. Accordingly, the total cost of fabricating ear prosthesis is about $30, which is much lower than the current soft prostheses fabrication methods.

  4. Analisis Kinerja Operasional Kereta Api Sriwedari Ekspress Jurusan Solo - Yogya

    Directory of Open Access Journals (Sweden)

    Bayu Rosida Sumantri

    2014-03-01

    Full Text Available Pada bulan Nopember 2012 PT. Kereta Api Indonesia (Persero DAOP 6 Yogyakarta mengoperasikan Kereta Api Sriwedari Ekspress dengan rute perjalanan Yogya – Solo, hal ini dilakukan untuk mengantisipasi lonjakan penumpang akibat pemangkasan rute perjalanan Kereta Api Prambanan Ekspress dari tiga belas kali perjalanan menjadi enam kali perjalanan. Menurut Humas PT. Kereta Api Indonesia (Persero DAOP 6 Yogyakarta, dibukanya rute baru Kereta Api Sriwedari Ekspress yang melayani delapan kali perjalanan hanya  dengan rute Yogya – Solo saja diharapkan kereta ini dapat memfasilitasi pergerakan penumpang antar dua daerah tersebut. Namun untuk mengetahui kinerja dari kereta api ini sesuai dengan Surat Keterangan Dirjen Perhubungan Darat No. 687 Tahun 2002, perlu ditinjau dari segi faktor muat, jumlah penumpang yang diangkut, waktu tunggu penumpang, ketepatan waktu kedatangan dan keberangkatan kereta dan kenyamanan penumpang. Dalam penelitian digunakan metode survey untuk mendapatkan nilai – nilai dari kinerja kereta api Sriwedari berupa survey observasi atau pengamatan lapangan.  Adapun  analisis yang digunakan untuk perhitungan waktu tempuh, waktu henti dan waktu tunda menggunakan uji hipotesis 1 sample t-test, karena uji ini paling memenuhi untuk melihat diterima atau tidaknya keterlambatan dari waktu kereta. Sedangkan untuk perhitungan load factor dan kenyamanan duduk dan berdiri berdasarkan perhitungan kapasitas dari Vukan R. Vuchic. Dari hasil analisis didapatkan waktu tempuh rata-rata untuk arah Yogyakarta selama 1 jam 14 menit dan untuk arah Solo selama 1 jam 12 menit. Waktu henti yang didapat dari seluruh jadwal perjalanan kereta arah Yogyakarta sebesar 3 menit, untuk arah Solo sebesar 5 menit. Waktu tunda dari seluruh perjalanan kereta Api Sriwedari untuk arah Yogyakarta didapat nilai waktu tunda kedatangan sebesar 22 menit dan nilai waktu tunda keberangkatan sebesar 20 menit, untuk arah Solo didapat nilai waktu tunda kedatangan sebesar 34

  5. When API Mass Spectrometry Meets Super Atmospheric Pressure Ion Sources

    Science.gov (United States)

    Chen, Lee Chuin

    2015-01-01

    In a tutorial paper on the application of free-jet technique for API-MS, John Fenn mentioned that “…for a number of years and a number of reasons, it has been found advantageous in many situations to carry out the ionization process in gas at pressures up to 1000 Torr or more” (Int. J. Mass Spectrom. 200: 459–478, 2000). In fact, the first ESI mass spectrometer constructed by Yamashita and Fenn had a counter-flow curtain gas source at 1050 Torr (ca. 1.4 atm) to sweep away the neutral (J. Phys. Chem. 88: 4451–4459, 1984). For gaseous ionization using electrospray plume, theoretical analysis also shows that “super-atmospheric operation would be more preferable in space-charge-limited situations.”(Int. J. Mass Spectrom. 300: 182–193, 2011). However, electrospray and the corona-based chemical ion source (APCI) in most commercial instrument are basically operated under an atmospheric pressure ambient, perhaps out of the concern of safety, convenience and simplicity in maintenance. Running the ion source at pressure much higher than 1 atm is not so common, but had been done by a number of groups as well as in our laboratory. A brief review on these ion sources will be given in this paper. PMID:26819912

  6. Comparative Sucrose Responsiveness in Apis mellifera and A. cerana Foragers

    Science.gov (United States)

    Yang, Wenchao; Kuang, Haiou; Wang, Shanshan; Wang, Jie; Liu, Wei; Wu, Zhenhong; Tian, Yuanyuan; Huang, Zachary Y.; Miao, Xiaoqing

    2013-01-01

    In the European honey bee, Apis mellifera, pollen foragers have a higher sucrose responsiveness than nectar foragers when tested using a proboscis extension response (PER) assay. In addition, Africanized honey bees have a higher sucrose responsiveness than European honey bees. Based on the biology of the Eastern honey bee, A. cerana, we hypothesized that A. cerana should also have a higher responsiveness to sucrose than A. mellifera. To test this hypothesis, we compared the sucrose thresholds of pollen foragers and nectar foragers in both A. cerana and A. mellifera in Fujian Province, China. Pollen foragers were more responsive to sucrose than nectar foragers in both species, consistent with previous studies. However, contrary to our hypothesis, A. mellifera was more responsive than A. cerana. We also demonstrated that this higher sucrose responsiveness in A. mellifera was not due to differences in the colony environment by co-fostering two species of bees in the same mixed-species colonies. Because A. mellifera foragers were more responsive to sucrose, we predicted that their nectar foragers should bring in less concentrated nectar compared to that of A. cerana. However, we found no differences between the two species. We conclude that A. cerana shows a different pattern in sucrose responsiveness from that of Africanized bees. There may be other mechanisms that enable A. cerana to perform well in areas with sparse nectar resources. PMID:24194958

  7. The defensive response of the honeybee Apis mellifera.

    Science.gov (United States)

    Nouvian, Morgane; Reinhard, Judith; Giurfa, Martin

    2016-11-15

    Honeybees (Apis mellifera) are insects living in colonies with a complex social organization. Their nest contains food stores in the form of honey and pollen, as well as the brood, the queen and the bees themselves. These resources have to be defended against a wide range of predators and parasites, a task that is performed by specialized workers, called guard bees. Guards tune their response to both the nature of the threat and the environmental conditions, in order to achieve an efficient trade-off between defence and loss of foraging workforce. By releasing alarm pheromones, they are able to recruit other bees to help them handle large predators. These chemicals trigger both rapid and longer-term changes in the behaviour of nearby bees, thus priming them for defence. Here, we review our current understanding on how this sequence of events is performed and regulated depending on a variety of factors that are both extrinsic and intrinsic to the colony. We present our current knowledge on the neural bases of honeybee aggression and highlight research avenues for future studies in this area. We present a brief overview of the techniques used to study honeybee aggression, and discuss how these could be used to gain further insights into the mechanisms of this behaviour. © 2016. Published by The Company of Biologists Ltd.

  8. Thermodynamic phase behavior of API/polymer solid dispersions.

    Science.gov (United States)

    Prudic, Anke; Ji, Yuanhui; Sadowski, Gabriele

    2014-07-07

    To improve the bioavailability of poorly soluble active pharmaceutical ingredients (APIs), these materials are often integrated into a polymer matrix that acts as a carrier. The resulting mixture is called a solid dispersion. In this work, the phase behaviors of solid dispersions were investigated as a function of the API as well as of the type and molecular weight of the carrier polymer. Specifically, the solubility of artemisinin and indomethacin was measured in different poly(ethylene glycol)s (PEG 400, PEG 6000, and PEG 35000). The measured solubility data and the solubility of sulfonamides in poly(vinylpyrrolidone) (PVP) K10 and PEG 35000 were modeled using the perturbed-chain statistical associating fluid theory (PC-SAFT). The results show that PC-SAFT predictions are in a good accordance with the experimental data, and PC-SAFT can be used to predict the whole phase diagram of an API/polymer solid dispersion as a function of the kind of API and polymer and of the polymer's molecular weight. This remarkably simplifies the screening process for suitable API/polymer combinations.

  9. Vitellogenins Are New High Molecular Weight Components and Allergens (Api m 12 and Ves v 6) of Apis mellifera and Vespula vulgaris Venom

    Science.gov (United States)

    Blank, Simon; Seismann, Henning; McIntyre, Mareike; Ollert, Markus; Wolf, Sara; Bantleon, Frank I.; Spillner, Edzard

    2013-01-01

    Background/Objectives Anaphylaxis due to hymenoptera stings is one of the most severe clinical outcomes of IgE-mediated hypersensitivity reactions. Although allergic reactions to hymenoptera stings are often considered as a general model for the underlying principles of allergic disease, venom immunotherapy is still hampered by severe systemic side effects and incomplete protection. The identification and detailed characterization of all allergens of hymenoptera venoms might result in an improvement in this field and promote the detailed understanding of the allergological mechanism. Our aim was the identification and detailed immunochemical and allergological characterization of the low abundant IgE-reactive 200 kDa proteins of Apis mellifera and Vespula vulgaris venom. Methods/Principal Findings Tandem mass spectrometry-based sequencing of a 200 kDa venom protein yielded peptides that could be assigned to honeybee vitellogenin. The coding regions of the honeybee protein as well as of the homologue from yellow jacket venom were cloned from venom gland cDNA. The newly identified 200 kDa proteins share a sequence identity on protein level of 40% and belong to the family of vitellogenins, present in all oviparous animals, and are the first vitellogenins identified as components of venom. Both vitellogenins could be recombinantly produced as soluble proteins in insect cells and assessed for their specific IgE reactivity. The particular vitellogenins were recognized by approximately 40% of sera of venom-allergic patients even in the absence of cross-reactive carbohydrate determinants. Conclusion With the vitellogenins of Apis mellifera and Vespula vulgaris venom a new homologous pair of venom allergens was identified and becomes available for future applications. Due to their allergenic properties the honeybee and the yellow jacket venom vitellogenin were designated as allergens Api m 12 and Ves v 6, respectively. PMID:23626765

  10. Development of API 5 CT grade P110 steel casing; Desenvolvimento de tubos casing API 5 CT grau P110

    Energy Technology Data Exchange (ETDEWEB)

    Kojima, Sergio Seijo; Roza, Juliana Espinossi

    2003-07-01

    This paper has as objective to discuss the results gotten in experiences carried through in industrial scale for the development of pipes class API 5CT P110 (1), with 244 mm of diameter and 12 mm of thickness. The pipes were welded longitudinally by process ERW (electric resistance welding) and submitted to quenching and tempering heat treatments. A C-Mn-Cr alloy with adequate quenching ability was used for the attainment of a martensite microstructure after quenching. The pipes at a temperature of 880 deg C were quenched in water and subsequently tempered at 515 deg C. The integrity of the weld region was evaluated through non destructive tests and flattening tests, Charpy impact tests and fracture toughness tests (CTOD). The pipes achieved the tension properties stipulated in the standard (yield strength bigger limit of 758 Mpa), and also the energy in the Charpy impact test (transversal), considering that the energy value obtained was 55 J (at 0 deg C) for base metal and 44 J in the weld metal. (author)

  11. Relationships between response surfaces for tablet characteristics of placebo and API-containing tablets manufactured by direct compression method.

    Science.gov (United States)

    Hayashi, Yoshihiro; Tsuji, Takahiro; Shirotori, Kaede; Oishi, Takuya; Kosugi, Atsushi; Kumada, Shungo; Hirai, Daijiro; Takayama, Kozo; Onuki, Yoshinori

    2017-10-30

    In this study, we evaluated the correlation between the response surfaces for the tablet characteristics of placebo and active pharmaceutical ingredient (API)-containing tablets. The quantities of lactose, cornstarch, and microcrystalline cellulose were chosen as the formulation factors. Ten tablet formulations were prepared. The tensile strength (TS) and disintegration time (DT) of tablets were measured as tablet characteristics. The response surfaces for TS and DT were estimated using a nonlinear response surface method incorporating multivariate spline interpolation, and were then compared with those of placebo tablets. A correlation was clearly observed for TS and DT of all APIs, although the value of the response surfaces for TS and DT was highly dependent on the type of API used. Based on this knowledge, the response surfaces for TS and DT of API-containing tablets were predicted from only two and four formulations using regression expression and placebo tablet data, respectively. The results from the evaluation of prediction accuracy showed that this method accurately predicted TS and DT, suggesting that it could construct a reliable response surface for TS and DT with a small number of samples. This technique assists in the effective estimation of the relationships between design variables and pharmaceutical responses during pharmaceutical development. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. A Process Analytical Technology (PAT) approach to control a new API manufacturing process: development, validation and implementation.

    Science.gov (United States)

    Schaefer, Cédric; Clicq, David; Lecomte, Clémence; Merschaert, Alain; Norrant, Edith; Fotiadu, Frédéric

    2014-03-01

    Pharmaceutical companies are progressively adopting and introducing Process Analytical Technology (PAT) and Quality-by-Design (QbD) concepts promoted by the regulatory agencies, aiming the building of the quality directly into the product by combining thorough scientific understanding and quality risk management. An analytical method based on near infrared (NIR) spectroscopy was developed as a PAT tool to control on-line an API (active pharmaceutical ingredient) manufacturing crystallization step during which the API and residual solvent contents need to be precisely determined to reach the predefined seeding point. An original methodology based on the QbD principles was designed to conduct the development and validation of the NIR method and to ensure that it is fitted for its intended use. On this basis, Partial least squares (PLS) models were developed and optimized using chemometrics methods. The method was fully validated according to the ICH Q2(R1) guideline and using the accuracy profile approach. The dosing ranges were evaluated to 9.0-12.0% w/w for the API and 0.18-1.50% w/w for the residual methanol. As by nature the variability of the sampling method and the reference method are included in the variability obtained for the NIR method during the validation phase, a real-time process monitoring exercise was performed to prove its fit for purpose. The implementation of this in-process control (IPC) method on the industrial plant from the launch of the new API synthesis process will enable automatic control of the final crystallization step in order to ensure a predefined quality level of the API. In addition, several valuable benefits are expected including reduction of the process time, suppression of a rather difficult sampling and tedious off-line analyses. © 2013 Published by Elsevier B.V.

  13. Safe “cloudification” of large images through picker APIs

    Science.gov (United States)

    Bremer, Erich; Kurc, Tahsin; Gao, Yi; Saltz, Joel; Almeida, Jonas S

    2016-01-01

    The “Box model” allows users with no particular training in informatics, or access to specialized infrastructure, operate generic cloud computing resources through a temporary URI dereferencing mechanism known as “drop-file-picker API” (“picker API” for sort). This application programming interface (API) was popularized in the web app development community by DropBox, and is now a consumer-facing feature of all major cloud computing platforms such as Box.com, Google Drive and Amazon S3. This reports describes a prototype web service application that uses picker APIs to expose a new, “cloudified”, API tailored for image analysis, without compromising the private governance of the data exposed. In order to better understand this cross-platform cloud computing landscape, we first measured the time for both transfer and traversing of large image files generated by whole slide imaging (WSI) in Digital Pathology. The verification that there is extensive interconnectivity between cloud resources let to the development of a prototype software application that exposes an image-traversing REST API to image files stored in any of the consumer-facing “boxes”. In summary, an image file can be upload/synchronized into a any cloud resource with a file picker API and the prototype service described here will expose an HTTP REST API that remains within the safety of the user’s own governance. The open source prototype is publicly available at sbu-bmi.github.io/imagebox. Availability The accompanying prototype application is made publicly available, fully functional, with open source, at http://sbu-bmi.github.io/imagebox://sbu-bmi.github.io/imagebox. An illustrative webcasted use of this Web App is included with the project codebase at https://github.com/SBU-BMI/imageboxs://github.com/SBU-BMI/imagebox. PMID:28269829

  14. Hydrogen sulfide corrosion of weld regions in API X52 steel; Corrosion por acido sulfhidrico de las regiones de soldadura en acero API X52

    Energy Technology Data Exchange (ETDEWEB)

    Arenas-Martinez, L.F [Universidad Autonoma de Coahuila, Coahuila (Mexico)]. E-mail: fernando.arenas@uadec.edu.mx; Garcia-Cerecero, G. [Corporacion Mexicana de Investigacion en Materiales S.A. de C.V., Saltillo, Coahuila (Mexico)]. E-mail: ggarcia@comimsa.com

    2012-10-15

    The corrosion behavior of gas metal arc welding (GMAW) regions has been studied using potentiodynamic polarization and polarization resistance (LPR) techniques. Experiments were conducted in hydrogen sulfide (H{sub 2}S)-containing brine and in H{sub 2}S-free brine. Welds were made on API 5L X52 steel. Due to differences in their microstructure, chemical composition and residual stress level, weld regions exhibited different responses under H{sub 2}S corrosion. Base metal exhibited the highest corrosion rate (CR) and the most cathodic corrosion potential. [Spanish] Se estudio el comportamiento ante la corrosion de las regiones de soldadura de un cordon realizado por arco metalico con gas (GMAW) sobre un acero grado API X52 mediante las tecnicas de polarizacion potencio dinamica y resistencia a la polarizacion (LPR). Los experimentos se realizaron utilizando salmuera con 300 ppm de acido sulfhidrico (H{sub 2}S) y salmuera libre de H{sub 2}S como electrolitos. Debido a las diferencias en su microestructura, composicion quimica y el nivel de esfuerzos residuales, las regiones de soldadura mostraron diferentes respuestas a la corrosion por H{sub 2}S. El metal base exhibio la velocidad de corrosion (VC) mas alta y el potencial de corrosion mas catodico.

  15. Api5 a new cofactor of estrogen receptor alpha involved in breast cancer outcome

    OpenAIRE

    Basset, C?line; Bonnet-Magnaval, Florence; Navarro, Marina Garcia-Jove; Touriol, Christian; Courtade, Monique; Prats, Herv?; Garmy-Susini, Barbara; Lacazette, Eric

    2017-01-01

    Api5 (Apoptosis inhibitor 5) is an anti-apoptotic factor that confers resistance to genotoxic stress in human cancer. Api5 is also expressed in endothelial cells and participates to the Estrogen Receptor ? (ER?) signaling to promote cell migration. In this study, we found an over expression of Api5 in human breast cancer. Given that we show that high expression of Api5 in breast cancer patients is associated with shorter recurrence free survival, we investigated the relationship between ER? a...

  16. Desktop analysis of potential impacts of visitor use: a case study for the highest park in the Southern Hemisphere.

    Science.gov (United States)

    Barros, Agustina; Pickering, Catherine; Gudes, Ori

    2015-03-01

    Nature-based tourism and recreation activities have a range of environmental impacts, but most protected area agencies have limited capacity to assess them. To prioritise where and what impacts to monitor and manage, we conducted a desktop assessment using Geographical Information Systems (GIS) by combining recreation ecology research with data on visitor usage and key environmental features for a popular protected area used for mountaineering and trekking, Aconcagua Provincial Park (2400-6962 m a.s.l.) in the Andes of Argentina. First, we integrated visitor data from permits with environmental data using GIS. We then identified key impact indicators for different activities based on the recreation ecology literature. Finally, we integrated this data to identify likely ecological impacts based on the types of activities, amount of use and altitudinal zones. Visitors only used 2% of the Park, but use was concentrated in areas of high conservation value including in alpine meadows and glacier lakes. Impacts on water resources were likely to be concentrated in campsites from the intermediate to the nival/glacial zones of the Park while impacts on terrestrial biodiversity were likely to be more severe in the low and intermediate alpine zones (2400-3800 m a.s.l.). These results highlight how visitor data can be used to identify priority areas for on-ground assessment of impacts in key locations. Improvements to the management of visitors in this Park involves more effective ways of dealing with water extraction and human waste in high altitude campsites and the impacts of hikers and pack animals in the low and intermediate alpine zones. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. On the reaction to deprecation of clients of 4 + 1 popular Java APIs and the JDK

    NARCIS (Netherlands)

    Sawant, A.A.; Robbes, Romain; Bacchelli, A.

    2017-01-01

    Application Programming Interfaces (APIs) are a tremendous resource—that is, when they are stable. Several studies have shown that this is unfortunately not the case. Of those, a large-scale study of API changes in the Pharo Smalltalk ecosystem documented several findings about API deprecations

  18. Using the rear projection of the Socibot Desktop robot for creation of applications with facial expressions

    Science.gov (United States)

    Gîlcă, G.; Bîzdoacă, N. G.; Diaconu, I.

    2016-08-01

    This article aims to implement some practical applications using the Socibot Desktop social robot. We mean to realize three applications: creating a speech sequence using the Kiosk menu of the browser interface, creating a program in the Virtual Robot browser interface and making a new guise to be loaded into the robot's memory in order to be projected onto it face. The first application is actually created in the Compose submenu that contains 5 file categories: audio, eyes, face, head, mood, this being helpful in the creation of the projected sequence. The second application is more complex, the completed program containing: audio files, speeches (can be created in over 20 languages), head movements, the robot's facial parameters function of each action units (AUs) of the facial muscles, its expressions and its line of sight. Last application aims to change the robot's appearance with the guise created by us. The guise was created in Adobe Photoshop and then loaded into the robot's memory.

  19. Advanced Stirling Radioisotope Generator Thermal Power Model in Thermal Desktop SINDA/FLUINT Analyzer

    Science.gov (United States)

    Wang, Xiao-Yen; Fabanich, William A.; Schmitz, Paul C.

    2012-01-01

    This paper presents a three-dimensional Advanced Stirling Radioisotope Generator (ASRG) thermal power model that was built using the Thermal Desktop SINDA/FLUINT thermal analyzer. The model was correlated with ASRG engineering unit (EU) test data and ASRG flight unit predictions from Lockheed Martin's Ideas TMG thermal model. ASRG performance under (1) ASC hot-end temperatures, (2) ambient temperatures, and (3) years of mission for the general purpose heat source fuel decay was predicted using this model for the flight unit. The results were compared with those reported by Lockheed Martin and showed good agreement. In addition, the model was used to study the performance of the ASRG flight unit for operations on the ground and on the surface of Titan, and the concept of using gold film to reduce thermal loss through insulation was investigated.

  20. Thermoelectric cooling of microelectronic circuits and waste heat electrical power generation in a desktop personal computer

    International Nuclear Information System (INIS)

    Gould, C.A.; Shammas, N.Y.A.; Grainger, S.; Taylor, I.

    2011-01-01

    Thermoelectric cooling and micro-power generation from waste heat within a standard desktop computer has been demonstrated. A thermoelectric test system has been designed and constructed, with typical test results presented for thermoelectric cooling and micro-power generation when the computer is executing a number of different applications. A thermoelectric module, operating as a heat pump, can lower the operating temperature of the computer's microprocessor and graphics processor to temperatures below ambient conditions. A small amount of electrical power, typically in the micro-watt or milli-watt range, can be generated by a thermoelectric module attached to the outside of the computer's standard heat sink assembly, when a secondary heat sink is attached to the other side of the thermoelectric module. Maximum electrical power can be generated by the thermoelectric module when a water cooled heat sink is used as the secondary heat sink, as this produces the greatest temperature difference between both sides of the module.

  1. Fabrication of cerebral aneurysm simulator with a desktop 3D printer.

    Science.gov (United States)

    Liu, Yu; Gao, Qing; Du, Song; Chen, ZiChen; Fu, JianZhong; Chen, Bing; Liu, ZhenJie; He, Yong

    2017-05-17

    Now, more and more patients are suffering cerebral aneurysm. However, long training time limits the rapid growth of cerebrovascular neurosurgeons. Here we developed a novel cerebral aneurysm simulator which can be better represented the dynamic bulging process of cerebral aneurysm The proposed simulator features the integration of a hollow elastic vascular model, a skull model and a brain model, which can be affordably fabricated at the clinic (Fab@Clinic), under $25.00 each with the help of a low-cost desktop 3D printer. Moreover, the clinical blood flow and pulsation pressure similar to the human can be well simulated, which can be used to train the neurosurgical residents how to clip aneurysms more effectively.

  2. Working Inside The Box: An Example Of Google Desktop Search in a Forensic Examination

    Directory of Open Access Journals (Sweden)

    Timothy James LaTulippe

    2011-12-01

    Full Text Available Information and the technological advancements for which mankind develops with regards to its storage has increased tremendously over the past few decades. As the total amount of data stored rapidly increases in conjunction with the amount of widely available computer-driven devices being used, solutions are being developed to better harness this data. These types of advancements are continually assisting investigators and computer forensic examiners. One such application which houses copious amounts of fruitful data is the Google Desktop Search program. Coupled with tested and verified techniques, examiners can exploit the power of this application to cater to their investigative needs. Please find within a real world case example of these techniques and its subsequent outcome.

  3. Surface acidity and solid-state compatibility of excipients with an acid-sensitive API: case study of atorvastatin calcium.

    Science.gov (United States)

    Govindarajan, Ramprakash; Landis, Margaret; Hancock, Bruno; Gatlin, Larry A; Suryanarayanan, Raj; Shalaev, Evgenyi Y

    2015-04-01

    The objectives of this study were to measure the apparent surface acidity of common excipients and to correlate the acidity with the chemical stability of an acid-sensitive active pharmaceutical ingredient (API) in binary API-excipient powder mixtures. The acidity of 26 solid excipients was determined by two methods, (i) by measuring the pH of their suspensions or solutions and (ii) the pH equivalent (pHeq) measured via ionization of probe molecules deposited on the surface of the excipients. The chemical stability of an API, atorvastatin calcium (AC), in mixtures with the excipients was evaluated by monitoring the appearance of an acid-induced degradant, atorvastatin lactone, under accelerated storage conditions. The extent of lactone formation in AC-excipient mixtures was presented as a function of either solution/suspension pH or pHeq. No lactone formation was observed in mixtures with excipients having pHeq > 6, while the lactone levels were pronounced (> 0.6% after 6 weeks at 50°C/20% RH) with excipients exhibiting pHeq 6, 3-6, and < 3) were consistent with the reported solution pH-stability profile of AC. In contrast to the pHeq scale, lactone formation did not show any clear trend when plotted as a function of the suspension/solution pH. Two mechanisms to explain the discrepancy between the suspension/solution pH and the chemical stability data were discussed. Acidic excipients, which are expected to be incompatible with an acid-sensitive API, were identified based on pHeq measurements. The incompatibility prediction was confirmed in the chemical stability tests using AC as an example of an acid-sensitive API.

  4. Assessing soil erosion risk using RUSLE through a GIS open source desktop and web application.

    Science.gov (United States)

    Duarte, L; Teodoro, A C; Gonçalves, J A; Soares, D; Cunha, M

    2016-06-01

    Soil erosion is a serious environmental problem. An estimation of the expected soil loss by water-caused erosion can be calculated considering the Revised Universal Soil Loss Equation (RUSLE). Geographical Information Systems (GIS) provide different tools to create categorical maps of soil erosion risk which help to study the risk assessment of soil loss. The objective of this study was to develop a GIS open source application (in QGIS), using the RUSLE methodology for estimating erosion rate at the watershed scale (desktop application) and provide the same application via web access (web application). The applications developed allow one to generate all the maps necessary to evaluate the soil erosion risk. Several libraries and algorithms from SEXTANTE were used to develop these applications. These applications were tested in Montalegre municipality (Portugal). The maps involved in RUSLE method-soil erosivity factor, soil erodibility factor, topographic factor, cover management factor, and support practices-were created. The estimated mean value of the soil loss obtained was 220 ton km(-2) year(-1) ranged from 0.27 to 1283 ton km(-2) year(-1). The results indicated that most of the study area (80 %) is characterized by very low soil erosion level (soil erosion was higher than 962 ton km(-2) year(-1). It was also concluded that areas with high slope values and bare soil are related with high level of erosion and the higher the P and C values, the higher the soil erosion percentage. The RUSLE web and the desktop application are freely available.

  5. Emission of particulate matter from a desktop three-dimensional (3D) printer.

    Science.gov (United States)

    Yi, Jinghai; LeBouf, Ryan F; Duling, Matthew G; Nurkiewicz, Timothy; Chen, Bean T; Schwegler-Berry, Diane; Virji, M Abbas; Stefaniak, Aleksandr B

    2016-01-01

    Desktop three-dimensional (3D) printers are becoming commonplace in business offices, public libraries, university labs and classrooms, and even private homes; however, these settings are generally not designed for exposure control. Prior experience with a variety of office equipment devices such as laser printers that emit ultrafine particles (UFP) suggests the need to characterize 3D printer emissions to enable reliable risk assessment. The aim of this study was to examine factors that influence particulate emissions from 3D printers and characterize their physical properties to inform risk assessment. Emissions were evaluated in a 0.5-m(3) chamber and in a small room (32.7 m(3)) using real-time instrumentation to measure particle number, size distribution, mass, and surface area. Factors evaluated included filament composition and color, as well as the manufacturer-provided printer emissions control technologies while printing an object. Filament type significantly influenced emissions, with acrylonitrile butadiene styrene (ABS) emitting larger particles than polylactic acid (PLA), which may have been the result of agglomeration. Geometric mean particle sizes and total particle (TP) number and mass emissions differed significantly among colors of a given filament type. Use of a cover on the printer reduced TP emissions by a factor of 2. Lung deposition calculations indicated a threefold higher PLA particle deposition in alveoli compared to ABS. Desktop 3D printers emit high levels of UFP, which are released into indoor environments where adequate ventilation may not be present to control emissions. Emissions in nonindustrial settings need to be reduced through the use of a hierarchy of controls, beginning with device design, followed by engineering controls (ventilation) and administrative controls such as choice of filament composition and color.

  6. A Collaborative Digital Pathology System for Multi-Touch Mobile and Desktop Computing Platforms

    KAUST Repository

    Jeong, W.

    2013-06-13

    Collaborative slide image viewing systems are becoming increasingly important in pathology applications such as telepathology and E-learning. Despite rapid advances in computing and imaging technology, current digital pathology systems have limited performance with respect to remote viewing of whole slide images on desktop or mobile computing devices. In this paper we present a novel digital pathology client-server system that supports collaborative viewing of multi-plane whole slide images over standard networks using multi-touch-enabled clients. Our system is built upon a standard HTTP web server and a MySQL database to allow multiple clients to exchange image and metadata concurrently. We introduce a domain-specific image-stack compression method that leverages real-time hardware decoding on mobile devices. It adaptively encodes image stacks in a decorrelated colour space to achieve extremely low bitrates (0.8 bpp) with very low loss of image quality. We evaluate the image quality of our compression method and the performance of our system for diagnosis with an in-depth user study. Collaborative slide image viewing systems are becoming increasingly important in pathology applications such as telepathology and E-learning. Despite rapid advances in computing and imaging technology, current digital pathology systems have limited performance with respect to remote viewing of whole slide images on desktop or mobile computing devices. In this paper we present a novel digital pathology client-server systems that supports collaborative viewing of multi-plane whole slide images over standard networks using multi-touch enabled clients. Our system is built upon a standard HTTP web server and a MySQL database to allow multiple clients to exchange image and metadata concurrently. © 2013 The Eurographics Association and John Wiley & Sons Ltd.

  7. Transcriptome analysis of the Asian honey bee Apis cerana cerana.

    Directory of Open Access Journals (Sweden)

    Zi Long Wang

    Full Text Available BACKGROUND: The Eastern hive honey bee, Apis cerana cerana is a native and widely bred honey bee species in China. Molecular biology research about this honey bee species is scarce, and genomic information for A. c. cerana is not currently available. Transcriptome and expression profiling data for this species are therefore important resources needed to better understand the biological mechanisms of A. c. cerana. In this study, we obtained the transcriptome information of A. c. cerana by RNA-sequencing and compared gene expression differences between queens and workers of A. c. cerana by digital gene expression (DGE analysis. RESULTS: Using high-throughput Illumina RNA sequencing we obtained 51,581,510 clean reads corresponding to 4.64 Gb total nucleotides from a single run. These reads were assembled into 46,999 unigenes with a mean length of 676 bp. Based on a sequence similarity search against the five public databases (NR, Swissport, GO, COG, KEGG with a cut-off E-value of 10(-5 using BLASTX, a total of 24,630 unigenes were annotated with gene descriptions, gene ontology terms, or metabolic pathways. Using these transcriptome data as references we analyzed the gene expression differences between the queens and workers of A. c. cerana using a tag-based digital gene expression method. We obtained 5.96 and 5.66 million clean tags from the queen and worker samples, respectively. A total of 414 genes were differentially expressed between them, with 189 up-regulated and 225 down-regulated in queens. CONCLUSIONS: Our transcriptome data provide a comprehensive sequence resource for future A. c. cerana study, establishing an important public information platform for functional genomic studies in A. c. cerana. Furthermore, the DGE data provide comprehensive gene expression information for the queens and workers, which will facilitate our understanding of the molecular mechanisms of the different physiological aspects of the two castes.

  8. The Taverna workflow suite: designing and executing workflows of Web Services on the desktop, web or in the cloud

    NARCIS (Netherlands)

    Wolstencroft, K.; Haines, R.; Fellows, D.; Williams, A.; Withers, D.; Owen, S.; Soiland-Reyes, S.; Dunlop, I.; Nenadic, A.; Fisher, P.; Bhagat, J.; Belhajjame, K.; Bacall, F.; Hardisty, A.; Nieva de la Hidalga, A.; Balcazar Vargas, M.P.; Sufi, S.; Goble, C.

    2013-01-01

    The Taverna workflow tool suite (http://www.taverna.org.uk) is designed to combine distributed Web Services and/or local tools into complex analysis pipelines. These pipelines can be executed on local desktop machines or through larger infrastructure (such as supercomputers, Grids or cloud

  9. No effect of ambient odor on the affective appraisal of a desktop virtual environment with signs of disorder

    NARCIS (Netherlands)

    Toet, A.; Schaik, M.G. van; Theunissen, N.C.M.

    2013-01-01

    Background : Desktop virtual environments (VEs) are increasingly deployed to study the effects of environmental qualities and interventions on human behavior and safety related concerns in built environments. For these applications it is essential that users appraise the affective qualities of the

  10. Influences of Gender and Computer Gaming Experience in Occupational Desktop Virtual Environments: A Cross-Case Analysis Study

    Science.gov (United States)

    Ausburn, Lynna J.; Ausburn, Floyd B.; Kroutter, Paul J.

    2013-01-01

    This study used a cross-case analysis methodology to compare four line-of-inquiry studies of desktop virtual environments (DVEs) to examine the relationships of gender and computer gaming experience to learning performance and perceptions. Comparison was made of learning patterns in a general non-technical DVE with patterns in technically complex,…

  11. The Learner Characteristics, Features of Desktop 3D Virtual Reality Environments, and College Chemistry Instruction: A Structural Equation Modeling Analysis

    Science.gov (United States)

    Merchant, Zahira; Goetz, Ernest T.; Keeney-Kennicutt, Wendy; Kwok, Oi-man; Cifuentes, Lauren; Davis, Trina J.

    2012-01-01

    We examined a model of the impact of a 3D desktop virtual reality environment on the learner characteristics (i.e. perceptual and psychological variables) that can enhance chemistry-related learning achievements in an introductory college chemistry class. The relationships between the 3D virtual reality features and the chemistry learning test as…

  12. Reach a New Threshold of Freedom and Control with Dell's Flexible Computing Solution: On-Demand Desktop Streaming

    Science.gov (United States)

    Technology & Learning, 2008

    2008-01-01

    When it comes to IT, there has always been an important link between data center control and client flexibility. As computing power increases, so do the potentially crippling threats to security, productivity and financial stability. This article talks about Dell's On-Demand Desktop Streaming solution which is designed to centralize complete…

  13. PrismTech Data Distribution Service Java API Evaluation

    Science.gov (United States)

    Riggs, Cortney

    2008-01-01

    My internship duties with Launch Control Systems required me to start performance testing of an Object Management Group's (OMG) Data Distribution Service (DDS) specification implementation by PrismTech Limited through the Java programming language application programming interface (API). DDS is a networking middleware for Real-Time Data Distribution. The performance testing involves latency, redundant publishers, extended duration, redundant failover, and read performance. Time constraints allowed only for a data throughput test. I have designed the testing applications to perform all performance tests when time is allowed. Performance evaluation data such as megabits per second and central processing unit (CPU) time consumption were not easily attainable through the Java programming language; they required new methods and classes created in the test applications. Evaluation of this product showed the rate that data can be sent across the network. Performance rates are better on Linux platforms than AIX and Sun platforms. Compared to previous C++ programming language API, the performance evaluation also shows the language differences for the implementation. The Java API of the DDS has a lower throughput performance than the C++ API.

  14. Enzymatic activities of Dermatophilus congolensis measured by API ZYM.

    Science.gov (United States)

    Hermoso de Mendoza, J; Arenas, A; Alonso, J M; Rey, J M; Gil, M C; Anton, J M; Hermoso de Mendoza, M

    1993-10-01

    API ZYM kit was used to test enzymatic activities on eighteen strains of Dermatophilus congolensis. All strains produced lipase and acid phosphatase, which act on lipids, and leucine arylamidase which act on proteins. Another 10 exoenzymes were present in at least one of the strains.

  15. Effects of Apis mellifera adansonii, L. 1758 (Apidae: Hymenoptera ...

    African Journals Online (AJOL)

    Effects of Apis mellifera adansonii, L. 1758 (Apidae: Hymenoptera) pollination on yields of Cucumeropsis mannii (Naudin) in Kisangani, Democratic Republic of Congo. Boniface Posho Ndola, Yves Brostaux, Guillaume Le Goff, Marie-Lucie Susini, Eric Haubruge, Frederic Francis, Bach Kim Nguyen ...

  16. Workers of Apis cerana reproduce during short periods of queenlessness.

    NARCIS (Netherlands)

    Boot, W.J.; Blom, van der J.; Beetsma, J.

    1997-01-01

    In six colonies of Apis cerana the queen was removed and occurrence of egg-laying by workers was studied. Three colonies had brood of all stages and were thus allowed to build emergency queen cells and to rear queens. In three other colonies no young brood to build emergency queen cells was left

  17. Physical stability of API/polymer-blend amorphous solid dispersions.

    Science.gov (United States)

    Lehmkemper, Kristin; Kyeremateng, Samuel O; Bartels, Mareike; Degenhardt, Matthias; Sadowski, Gabriele

    2018-03-01

    The preparation of amorphous solid dispersions (ASDs) is a well-established strategy for formulating active pharmaceutical ingredients by embedding them in excipients, usually amorphous polymers. Different polymers can be combined for designing ASDs with desired properties like an optimized dissolution behavior. One important criterion for the development of ASD compositions is the physical stability. In this work, the physical stability of API/polymer-blend ASDs was investigated by thermodynamic modeling and stability studies. Amorphous naproxen (NAP) and acetaminophen (APAP) were embedded in blends of hydroxypropyl methylcellulose acetate succinate (HPMCAS) and either poly(vinylpyrrolidone) (PVP) or poly(vinylpyrrolidone-co-vinyl acetate) (PVPVA64). Parameters for modeling the API solubility in the blends and the glass-transition temperature curves of the water-free systems with Perturbed-Chain Statistical Associating Fluid Theory and Kwei equation, respectively, were correlated to experimental data. The phase behavior for standardized storage conditions (0%, 60% and 75% relative humidity (RH)) was predicted and compared to six months-long stability studies. According to modeling and experimental results, the physical stability was reduced with increasing HPMCAS content and increasing RH. This trend was observed for all investigated systems, with both APIs (NAP and APAP) and both polymer blends (PVP/HPMCAS and PVPVA64/HPMCAS). PC-SAFT and the Kwei equation turned out to be suitable tools for modeling and predicting the physical stability of the investigated API/polymer-blends ASDs. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. One implementation of API interface for RouterOS

    Directory of Open Access Journals (Sweden)

    Gencho Stoitsov

    2014-05-01

    Full Text Available The purpose of this publication is to present the implementation of API interface for RouterOS of the company MikroTik, which allows using PHP scripts for obtaining data for configuration and management of the routing devices that use this OS.

  19. JASPAR RESTful API: accessing JASPAR data from any programming language.

    Science.gov (United States)

    Khan, Aziz; Mathelier, Anthony

    2017-12-15

    JASPAR is a widely used open-access database of curated, non-redundant transcription factor binding profiles. Currently, data from JASPAR can be retrieved as flat files or by using programming language-specific interfaces. Here, we present a programming language-independent application programming interface (API) to access JASPAR data using the Representational State Transfer (REST) architecture. The REST API enables programmatic access to JASPAR by most programming languages and returns data in eight widely used formats. Several endpoints are available to access the data and an endpoint is available to infer the TF binding profile(s) likely bound by a given DNA binding domain protein sequence. Additionally, it provides an interactive browsable interface for bioinformatics tool developers. This REST API is implemented in Python using the Django REST Framework. It is accessible at http://jaspar.genereg.net/api/ and the source code is freely available at https://bitbucket.org/CBGR/jaspar under GPL v3 license. aziz.khan@ncmm.uio.no, anthony.mathelier@ncmm.uio.no. Supplementary data are available at Bioinformatics online. © The Author (2017). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  20. Modelling the subgenual organ of the honeybee, Apis mellifera

    DEFF Research Database (Denmark)

    Storm, Jesper; Kilpinen, Ole

    1998-01-01

    In a recent study on the honeybee (Apis mellifera), the subgenual organ was observed moving inside the leg during sinusoidal vibrations of the leg (Kilpinen and Storm 1997). The subgenual organ of the honeybee is suspended in a haemolymph channel in the tibia of each leg. When the leg accelerates...

  1. Studies on the life cycle and morphometrics of honeybees, Apis ...

    African Journals Online (AJOL)

    The life cycle of the honeybee, Apis mellifera adansonii, was studied in mangrove area by monitoring the developmental stages and morphology of the castes. It was observed that the fate of the eggs were predetermined at the onset leading to drones, queens or workers. It was also established that the three different castes ...

  2. Improving honey production in worker bees (Apis mellifera adansoni ...

    African Journals Online (AJOL)

    Modification of feeding activity, nursing care and undertaker behaviour were carried out among some colonies of honey bees Apis mellifera adansoni L to know the effect on honey production. Apiaries Numbers 1, 2 and 3 contain three replicates of experimental hives while apiary Number 4 contains control hives. All the ...

  3. Sperm use economy of honeybee (Apis mellifera) queens

    DEFF Research Database (Denmark)

    Baer, Boris; Collins, Jason; Maalaps, Kristiina

    2016-01-01

    the fecundity and longevity of queens and therefore colony fitness. We quantified the number of sperm that honeybee (Apis mellifera) queens use to fertilize eggs. We examined sperm use in naturally mated queens of different ages and in queens artificially inseminated with different volumes of semen. We found...

  4. A survey of the ethnozoological knowledge of honey bees Apis ...

    African Journals Online (AJOL)

    A survey of the ethnozoological knowledge of honey bee Apis mellifera in Ijebu division of South western Nigeria was carried out to examine the pattern of invasion, control methods of their invasion and their effects in life and economy of the people which also include the medicinal and traditional utilization. The Survey was ...

  5. Nosema Tolerant Honeybees (Apis mellifera) Escape Parasitic Manipulation of Apoptosis

    DEFF Research Database (Denmark)

    Kurze, Christoph; Le Conte, Yves; Dussaubat, Claudia

    2015-01-01

    conducted three inoculation experiments to investigate in the apoptotic respond during infection with the intracellular gut pathogen Nosema ceranae, which is considered as potential global threat to the honeybee (Apis mellifera) and other bee pollinators, in sensitive and tolerant honeybees. To explore...

  6. Biophysics of the subgenual organ of the honeybee, Apis mellifera

    DEFF Research Database (Denmark)

    Kilpinen, Ole; Storm, Jesper

    1997-01-01

    The subgenual organ of the honeybee (Apis mellifera) is suspended in a haemolymph channel in the tibia of each leg. When the leg is accelerated, inertia causes the haemolymph (and the subgenual organ) to lag behind the movement of the rest of the leg. The magnitude of this phase lag determines...

  7. Foraging and pollination behaviour of the African Honey bee ( Apis ...

    African Journals Online (AJOL)

    Foraging and pollination behaviour of the African Honey bee (Apis mellifera adansonii) on Callistemon rigidus flowers in Ngaoundere (Cameroon). F-N Tchuenguem Fohouo, J Messi, D Brüchner, B Bouba, G Mbofung, J Hentchoya Hemo. Abstract. No Abstract Available Journal of the Cameroon Academy of Sciences ...

  8. Effect of age of honeybee queens of Apis mellifera adansonii ...

    African Journals Online (AJOL)

    The effect of age of honeybee queens of Apis mellifera adansonii on rate of brood production was studied using Langstroth hives. Brood productivity of young queens (24 days old) and old queens (18 months old) was investigated and compared by extrapolating the brood areas covered as equivalent to the number of eggs ...

  9. Effects of honeybee ( Apis mellifera ) pollination on seed set in ...

    African Journals Online (AJOL)

    This study was carried out to determine the efficiency of pollination with honeybee (Apis mellifera) on sunflower hybrid seed production under different types of pollination during 2005 and 2006 in Mustafakemalpasa-Bursa, Turkey. Three pollination types (1) in cages with honeybees, (2) hand pollination (in cages) and (3) in ...

  10. Assessment of nutritional resources quality from honeybees ( Apis ...

    African Journals Online (AJOL)

    Assessment of nutritional resources quality from honeybees ( Apis mellifera adansonii , L. 1758: Hymenoptera, Apidae) in three beekeeping sites of the Democratic Republic of Congo. ... No significant difference was observed between Kisangani, Mampu and Kavwaya in terms of protein content of beebread (P ≥ 0.05).

  11. Silk formation mechanisms in the larval salivary glands of Apis ...

    Indian Academy of Sciences (India)

    Unknown

    The mechanism of silk formation in Apis mellifera salivary glands, during the 5th instar, was studied. Larval salivary glands were dissected and prepared for light and polarized light microscopy, as well as for scanning and transmission electron microscopy. The results showed that silk formation starts at the middle of the 5th ...

  12. ANALISA PEREKAMAN DATA SUARA DARI SISTEM BLACKBOX PADA KERETA API

    Directory of Open Access Journals (Sweden)

    Emy Setyaningsih

    2016-01-01

    Full Text Available             Makalah ini akan membahas tentang penerapan black box pada kereta api yang diadopsi pertama kali pada pesawat, dengan parameter perekam suara hingga waktu simpan kurang dari 1 hari 8 jam pada media penyimpanan SD Card. Tujuan dari pengujian pada makalah ini adalah membandingkan sumber suara terhadap jarak penerima, sebagai parameter perubahan tingkat suara “dB”. Sistem perekaman suara yang akan ditempatkan pada kereta api ini menggunakan modul rangkaian terintregasi WTR010. Voice record WTR010 merupakan modul rangkaian terintegrasi untuk merekam suara sendiri atau pun suara dari file music / video pada komputer dengan sangat mudah. Modul ini bisa merekam suara sendiri dan langsung di simpan ke dalam format audio. Format audio yang disediakan oleh modul voice record adalah format AD4 dan wav. Hasil pengujian modul black box yang diletakkan pada kereta api, dengan mencoba mengucapkan kata  “SAYA”,  suara dapat terekam pada modul perekam suara yang selanjutnya diolah menggunakan ”software sound editor” yang disimpan pada SD Card ber-ekstensi “wav”. Perbandingan sumber suara terhadap jarak penerima dari pengujian didapatkan sebuah persamaan regresi linier  y = -( 31x – 11  dan R² = 0.972.  Pengujian ini menghasilkan penekanan suara dB dan frekuensi sample Hz yang berbeda.  Kata kunci: black box kereta api, perekaman suara, WTR010

  13. Standard methods for research on apis mellifera gut symbionts

    Science.gov (United States)

    Gut microbes can play an important role in digestion, disease resistance, and the general health of animals, but little is known about the biology of gut symbionts in Apis mellifera. This paper is part of a series on honey bee research methods, providing protocols for studying gut symbionts. We desc...

  14. Standard methods for research on Apis mellifera gut symbionts

    Science.gov (United States)

    Gut microbes can play an important role in digestion, disease resistance, and the general health of animals, but little is known about the biology of gut symbionts in Apis mellifera. This paper is part of a series on honey bee research methods, providing protocols for studying gut symbionts. We desc...

  15. Silk formation mechanisms in the larval salivary glands of Apis ...

    Indian Academy of Sciences (India)

    Keywords. Bee; electron microscopy; larval salivary gland; light microscopy; polarized light microscopy; silk gland. Abstract. The mechanism of silk formation in Apis mellifera salivary glands, during the 5th instar, was studied. Larval salivary glands were dissected and prepared for light and polarized light microscopy, as well ...

  16. Pathogen detection and gut bacteria identification in Apis cerana ...

    African Journals Online (AJOL)

    A total of 50 colonies of Apis cerana were sampled in Samut Songkhram (five colonies) and Chumphon (45 colonies) provinces in the central and the south of Thailand, respectively. Diagnostic multiplex polymerase chain reaction (PCR) revealed that 20, 6, 4, 20 and 0% of the samples were infected by Paenibacillus larvae, ...

  17. Constructing a Computer-Aided Differential Diagnosis Engine from Open-Source APIs.

    Science.gov (United States)

    Morrison, James J; Hostetter, Jason M; Aggarwal, Abhi; Filice, Ross W

    2016-12-01

    This paper describes the design and implementation of an application that parses and analyzes radiology report text to provide a radiologic differential diagnosis. The system was constructed using a combination of freely available web-based APIs and originally developed during the Society for Imaging Informatics in Medicine (SIIM) 2014 Hackathon. Continued development has refined and increased the accuracy of the algorithm. This project demonstrates the power and possibilities of combining existing technologies to solve unique problems as well as the stimulus of the hackathon setting to spur innovation.

  18. Hydrogen Sulfide Corrosion of Weld Regions in API X52 Steel

    Directory of Open Access Journals (Sweden)

    García-Cerecero G.

    2012-10-01

    Full Text Available The corrosion behavior of gas metal arc welding (GMAW regions has been studied using potentiodynamic polarization and polarization resistance (LPR techniques. Experiments were conducted in hydrogen sulfide (H2S-containing brine and in H2S-free brine. Welds were made on API 5L X52 steel. Due to differences in their microstructure, chemical composition and residual stress level, weld regions exhibited different responses under H2S corrosion. Base metal exhibited the highest corrosion rate (CR and the most cathodic corrosion potential.

  19. Detection of Illicit Drugs by Trained Honeybees (Apis mellifera.

    Directory of Open Access Journals (Sweden)

    Matthias Schott

    Full Text Available Illegal drugs exacerbate global social challenges such as substance addiction, mental health issues and violent crime. Police and customs officials often rely on specially-trained sniffer dogs, which act as sensitive biological detectors to find concealed illegal drugs. However, the dog "alert" is no longer sufficient evidence to allow a search without a warrant or additional probable cause because cannabis has been legalized in two US states and is decriminalized in many others. Retraining dogs to recognize a narrower spectrum of drugs is difficult and training new dogs is time consuming, yet there are no analytical devices with the portability and sensitivity necessary to detect substance-specific chemical signatures. This means there is currently no substitute for sniffer dogs. Here we describe an insect screening procedure showing that the western honeybee (Apis mellifera can sense volatiles associated with pure samples of heroin and cocaine. We developed a portable electroantennographic device for the on-site measurement of volatile perception by these insects, and found a positive correlation between honeybee antennal responses and the concentration of specific drugs in test samples. Furthermore, we tested the ability of honeybees to learn the scent of heroin and trained them to show a reliable behavioral response in the presence of a highly-diluted scent of pure heroin. Trained honeybees could therefore be used to complement or replace the role of sniffer dogs as part of an automated drug detection system. Insects are highly sensitive to volatile compounds and provide an untapped resource for the development of biosensors. Automated conditioning as presented in this study could be developed as a platform for the practical detection of illicit drugs using insect-based sensors.

  20. Student project of optical system analysis API-library development

    Science.gov (United States)

    Ivanova, Tatiana; Zhukova, Tatiana; Dantcaranov, Ruslan; Romanova, Maria; Zhadin, Alexander; Ivanov, Vyacheslav; Kalinkina, Olga

    2017-08-01

    In the paper API-library software developed by students of Applied and Computer Optics Department (ITMO University) for optical system design is presented. The library performs paraxial and real ray tracing, calculates 3d order (Seidel) aberration and real ray aberration of axis and non-axis beams (wave, lateral, longitudinal, coma, distortion etc.) and finally, approximate wave aberration by Zernike polynomials. Real aperture can be calculated by considering of real rays tracing failure on each surface. So far we assume optical system is centered, with spherical or 2d order aspherical surfaces. Optical glasses can be set directly by refraction index or by dispersion coefficients. The library can be used for education or research purposes in optical system design area. It provides ready to use software functions for optical system simulation and analysis that developer can simply plug into their software development for different purposes, for example for some specific synthesis tasks or investigation of new optimization modes. In the paper we present an example of using the library for development of cemented doublet synthesis software based on Slusarev's methodology. The library is used in optical system optimization recipes course for deep studying of optimization model and its application for optical system design. Development of such software is an excellent experience for students and help to understanding optical image modeling and quality analysis. This development is organized as student group joint project. We try to organize it as a group in real research and development project, so each student has his own role in the project and then use whole library functionality in his own master or bachelor thesis. Working in such group gives students useful experience and opportunity to work as research and development engineer of scientific software in the future.

  1. Acaricide, fungicide and drug interactions in honey bees (Apis mellifera.

    Directory of Open Access Journals (Sweden)

    Reed M Johnson

    Full Text Available BACKGROUND: Chemical analysis shows that honey bees (Apis mellifera and hive products contain many pesticides derived from various sources. The most abundant pesticides are acaricides applied by beekeepers to control Varroa destructor. Beekeepers also apply antimicrobial drugs to control bacterial and microsporidial diseases. Fungicides may enter the hive when applied to nearby flowering crops. Acaricides, antimicrobial drugs and fungicides are not highly toxic to bees alone, but in combination there is potential for heightened toxicity due to interactive effects. METHODOLOGY/PRINCIPAL FINDINGS: Laboratory bioassays based on mortality rates in adult worker bees demonstrated interactive effects among acaricides, as well as between acaricides and antimicrobial drugs and between acaricides and fungicides. Toxicity of the acaricide tau-fluvalinate increased in combination with other acaricides and most other compounds tested (15 of 17 while amitraz toxicity was mostly unchanged (1 of 15. The sterol biosynthesis inhibiting (SBI fungicide prochloraz elevated the toxicity of the acaricides tau-fluvalinate, coumaphos and fenpyroximate, likely through inhibition of detoxicative cytochrome P450 monooxygenase activity. Four other SBI fungicides increased the toxicity of tau-fluvalinate in a dose-dependent manner, although possible evidence of P450 induction was observed at the lowest fungicide doses. Non-transitive interactions between some acaricides were observed. Sublethal amitraz pre-treatment increased the toxicity of the three P450-detoxified acaricides, but amitraz toxicity was not changed by sublethal treatment with the same three acaricides. A two-fold change in the toxicity of tau-fluvalinate was observed between years, suggesting a possible change in the genetic composition of the bees tested. CONCLUSIONS/SIGNIFICANCE: Interactions with acaricides in honey bees are similar to drug interactions in other animals in that P450-mediated detoxication

  2. Acaricide, fungicide and drug interactions in honey bees (Apis mellifera).

    Science.gov (United States)

    Johnson, Reed M; Dahlgren, Lizette; Siegfried, Blair D; Ellis, Marion D

    2013-01-01

    Chemical analysis shows that honey bees (Apis mellifera) and hive products contain many pesticides derived from various sources. The most abundant pesticides are acaricides applied by beekeepers to control Varroa destructor. Beekeepers also apply antimicrobial drugs to control bacterial and microsporidial diseases. Fungicides may enter the hive when applied to nearby flowering crops. Acaricides, antimicrobial drugs and fungicides are not highly toxic to bees alone, but in combination there is potential for heightened toxicity due to interactive effects. Laboratory bioassays based on mortality rates in adult worker bees demonstrated interactive effects among acaricides, as well as between acaricides and antimicrobial drugs and between acaricides and fungicides. Toxicity of the acaricide tau-fluvalinate increased in combination with other acaricides and most other compounds tested (15 of 17) while amitraz toxicity was mostly unchanged (1 of 15). The sterol biosynthesis inhibiting (SBI) fungicide prochloraz elevated the toxicity of the acaricides tau-fluvalinate, coumaphos and fenpyroximate, likely through inhibition of detoxicative cytochrome P450 monooxygenase activity. Four other SBI fungicides increased the toxicity of tau-fluvalinate in a dose-dependent manner, although possible evidence of P450 induction was observed at the lowest fungicide doses. Non-transitive interactions between some acaricides were observed. Sublethal amitraz pre-treatment increased the toxicity of the three P450-detoxified acaricides, but amitraz toxicity was not changed by sublethal treatment with the same three acaricides. A two-fold change in the toxicity of tau-fluvalinate was observed between years, suggesting a possible change in the genetic composition of the bees tested. Interactions with acaricides in honey bees are similar to drug interactions in other animals in that P450-mediated detoxication appears to play an important role. Evidence of non-transivity, year-to-year variation

  3. A radio frequency signal driver for quadrupole used in desktop orthogonal-injection time-of-flight mass spectrometer

    International Nuclear Information System (INIS)

    Guo, Changjuan; Jiang, Zhongyao; Xie, Chunguang; Zhu, Hui; Gao, Wei; Huang, Zhengxu; Cheng, Ping; Fu, Zhong; Zhou, Zhen

    2012-01-01

    According to the demand of home-made spectrometer, a radio frequency (RF) signal driver was developed. This RF signal driver is composed of signal generating circuit, signal amplification circuit and power output circuit, to drive the radio frequency quadrupole (RFQ). The designed RFQ is used to transfer ions generated in atmospheric pressure ion source to a home-made desktop orthogonal-injection time-of-flight mass analyzer. This signal driver is divided into low-frequency part and high-frequency part to support RFQ transferring ions of larger values (i.e., m/z=100–600) and smaller values (i.e., m/z=20–100) respectively. The low-frequency part of the RF signal driver can provide RF signals with resonance frequency of 1.43 MHz, peak to peak voltage V p–p of 0–1080 V, and the high-frequency part can provide RF signals with resonance frequency of 2.05 MHz, peak to peak voltage V p–p of 0–520 V. With the radio frequency signal driver described in this paper, ions in the range m/z 20–600 can be transmitted efficiently by RFQ. -- Highlights: ► According to the demand of home-made TOF MS, a radio frequency (RF) signal driver was developed. ► First, we calculated by the theory to determine the parameters, then based on the calculations designed the RF circuit and built it, finally tested the results. ► Found in practice, the theoretical calculations of the air core coil inductances are very close to the actual results. ► The RF circuit built is cheap, compact, stable, and easy to adjust according to the different needs of the TOF MS.

  4. Design and assessment of a novel SPECT system for desktop open-gantry imaging of small animals: A simulation study

    Energy Technology Data Exchange (ETDEWEB)

    Zeraatkar, Navid; Farahani, Mohammad Hossein [Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran 1419733141 (Iran, Islamic Republic of); Rahmim, Arman [Department of Radiology, Johns Hopkins University, Baltimore, Maryland 21287 and Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, Maryland 21218 (United States); Sarkar, Saeed [Department of Medical Physics and Biomedical Engineering, Tehran University of Medical Sciences, Tehran 1417613151, Iran and Research Center for Science and Technology in Medicine, Tehran University of Medical Sciences, Tehran 1419733141 (Iran, Islamic Republic of); Ay, Mohammad Reza, E-mail: mohammadreza-ay@sina.tums.ac.ir [Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran 1419733141, Iran and Department of Medical Physics and Biomedical Engineering, Tehran University of Medical Sciences, Tehran 1417613151 (Iran, Islamic Republic of)

    2016-05-15

    Purpose: Given increasing efforts in biomedical research utilizing molecular imaging methods, development of dedicated high-performance small-animal SPECT systems has been growing rapidly in the last decade. In the present work, we propose and assess an alternative concept for SPECT imaging enabling desktop open-gantry imaging of small animals. Methods: The system, PERSPECT, consists of an imaging desk, with a set of tilted detector and pinhole collimator placed beneath it. The object to be imaged is simply placed on the desk. Monte Carlo (MC) and analytical simulations were utilized to accurately model and evaluate the proposed concept and design. Furthermore, a dedicated image reconstruction algorithm, finite-aperture-based circular projections (FABCP), was developed and validated for the system, enabling more accurate modeling of the system and higher quality reconstructed images. Image quality was quantified as a function of different tilt angles in the acquisition and number of iterations in the reconstruction algorithm. Furthermore, more complex phantoms including Derenzo, Defrise, and mouse whole body were simulated and studied. Results: The sensitivity of the PERSPECT was 207 cps/MBq. It was quantitatively demonstrated that for a tilt angle of 30°, comparable image qualities were obtained in terms of normalized squared error, contrast, uniformity, noise, and spatial resolution measurements, the latter at ∼0.6 mm. Furthermore, quantitative analyses demonstrated that 3 iterations of FABCP image reconstruction (16 subsets/iteration) led to optimally reconstructed images. Conclusions: The PERSPECT, using a novel imaging protocol, can achieve comparable image quality performance in comparison with a conventional pinhole SPECT with the same configuration. The dedicated FABCP algorithm, which was developed for reconstruction of data from the PERSPECT system, can produce high quality images for small-animal imaging via accurate modeling of the system as

  5. Sensor Observation Service API for Providing Gridded Climate Data to Agricultural Applications

    Directory of Open Access Journals (Sweden)

    Rassarin Chinnachodteeranun

    2016-08-01

    Full Text Available We developed a mechanism for seamlessly providing weather data and long-term historical climate data from a gridded data source through an international standard web API, which was the Sensor Observation Service (SOS defined by the Open Geospatial Consortium (OGC. The National Agriculture and Food Research Organization (NARO Japan has been providing gridded climate data consisting of nine daily meteorological variables, which are average, minimum, maximum of air temperature, relative humidity, sunshine duration, solar radiant exposure, downward longwave radiation, precipitation and wind speed for 35 years covering Japan. The gridded data structure is quite useful for spatial analysis, such as developing crop suitability maps and monitoring regional crop development. Individual farmers, however, make decisions using historical climate information and forecasts for an incoming cropping season of their farms. In this regard, climate data at a point-based structure are convenient for application development to support farmers’ decisions. Through the proposed mechanism in this paper, the agricultural applications and analysis can request point-based climate data from a gridded data source through the standard API with no need to deal with the complicated hierarchical data structure of the gridded climate data source. Clients can easily obtain data and metadata by only accessing the service endpoint. The mechanism also provides several web bindings and data encodings for the clients’ convenience. Caching, including the pre-caching mechanism, was developed and evaluated to secure an effective response time. The mechanism enhances the accessibility and usability of the gridded weather data source, as well as SOS API for agricultural applications.

  6. Accessing the SEED genome databases via Web services API: tools for programmers.

    Science.gov (United States)

    Disz, Terry; Akhter, Sajia; Cuevas, Daniel; Olson, Robert; Overbeek, Ross; Vonstein, Veronika; Stevens, Rick; Edwards, Robert A

    2010-06-14

    The SEED integrates many publicly available genome sequences into a single resource. The database contains accurate and up-to-date annotations based on the subsystems concept that leverages clustering between genomes and other clues to accurately and efficiently annotate microbial genomes. The backend is used as the foundation for many genome annotation tools, such as the Rapid Annotation using Subsystems Technology (RAST) server for whole genome annotation, the metagenomics RAST server for random community genome annotations, and the annotation clearinghouse for exchanging annotations from different resources. In addition to a web user interface, the SEED also provides Web services based API for programmatic access to the data in the SEED, allowing the development of third-party tools and mash-ups. The currently exposed Web services encompass over forty different methods for accessing data related to microbial genome annotations. The Web services provide comprehensive access to the database back end, allowing any programmer access to the most consistent and accurate genome annotations available. The Web services are deployed using a platform independent service-oriented approach that allows the user to choose the most suitable programming platform for their application. Example code demonstrate that Web services can be used to access the SEED using common bioinformatics programming languages such as Perl, Python, and Java. We present a novel approach to access the SEED database. Using Web services, a robust API for access to genomics data is provided, without requiring large volume downloads all at once. The API ensures timely access to the most current datasets available, including the new genomes as soon as they come online.

  7. Accessing the SEED Genome Databases via Web Services API: Tools for Programmers

    Directory of Open Access Journals (Sweden)

    Vonstein Veronika

    2010-06-01

    Full Text Available Abstract Background The SEED integrates many publicly available genome sequences into a single resource. The database contains accurate and up-to-date annotations based on the subsystems concept that leverages clustering between genomes and other clues to accurately and efficiently annotate microbial genomes. The backend is used as the foundation for many genome annotation tools, such as the Rapid Annotation using Subsystems Technology (RAST server for whole genome annotation, the metagenomics RAST server for random community genome annotations, and the annotation clearinghouse for exchanging annotations from different resources. In addition to a web user interface, the SEED also provides Web services based API for programmatic access to the data in the SEED, allowing the development of third-party tools and mash-ups. Results The currently exposed Web services encompass over forty different methods for accessing data related to microbial genome annotations. The Web services provide comprehensive access to the database back end, allowing any programmer access to the most consistent and accurate genome annotations available. The Web services are deployed using a platform independent service-oriented approach that allows the user to choose the most suitable programming platform for their application. Example code demonstrate that Web services can be used to access the SEED using common bioinformatics programming languages such as Perl, Python, and Java. Conclusions We present a novel approach to access the SEED database. Using Web services, a robust API for access to genomics data is provided, without requiring large volume downloads all at once. The API ensures timely access to the most current datasets available, including the new genomes as soon as they come online.

  8. EXPERIENCE API – NEW STANDARD OF E-LEARNING SOFTWARE AND EXAMPLES OF ITS PRACTICAL USE

    Directory of Open Access Journals (Sweden)

    Oleksandr A. Shcherbyna

    2016-07-01

    Full Text Available The purpose of the article is to analyze features of the new standard of e-learning software - Experience API (xAPI, previously also known as the Tin Can API. The standard defines a way of interaction between xAPI-clients – software which students work with while e-learning process, and xAPI-servers – Learning Record Stores (LRS, which store data about their results. Standard also defines LRS data representation format and a way of data transfers between LRS, which makes it possible to combine several LRS into distributed database that could accumulate information about people training in formal, non-formal and informal education throughout life. The article contains review of available xAPI-clients, xAPI-servers, and the results of their testing, which prove the possibility of their usage in our educational institutions.

  9. Cross-linking BioThings APIs through JSON-LD to facilitate knowledge exploration.

    Science.gov (United States)

    Xin, Jiwen; Afrasiabi, Cyrus; Lelong, Sebastien; Adesara, Julee; Tsueng, Ginger; Su, Andrew I; Wu, Chunlei

    2018-02-01

    Application Programming Interfaces (APIs) are now widely used to distribute biological data. And many popular biological APIs developed by many different research teams have adopted Javascript Object Notation (JSON) as their primary data format. While usage of a common data format offers significant advantages, that alone is not sufficient for rich integrative queries across APIs. Here, we have implemented JSON for Linking Data (JSON-LD) technology on the BioThings APIs that we have developed, MyGene.info , MyVariant.info and MyChem.info . JSON-LD provides a standard way to add semantic context to the existing JSON data structure, for the purpose of enhancing the interoperability between APIs. We demonstrated several use cases that were facilitated by semantic annotations using JSON-LD, including simpler and more precise query capabilities as well as API cross-linking. We believe that this pattern offers a generalizable solution for interoperability of APIs in the life sciences.

  10. Design and implementation of handheld and desktop software for the structured reporting of hepatic masses using the LI-RADS schema.

    Science.gov (United States)

    Clark, Toshimasa J; McNeeley, Michael F; Maki, Jeffrey H

    2014-04-01

    The Liver Imaging Reporting and Data System (LI-RADS) can enhance communication between radiologists and clinicians if applied consistently. We identified an institutional need to improve liver imaging report standardization and developed handheld and desktop software to serve this purpose. We developed two complementary applications that implement the LI-RADS schema. A mobile application for iOS devices written in the Objective-C language allows for rapid characterization of hepatic observations under a variety of circumstances. A desktop application written in the Java language allows for comprehensive observation characterization and standardized report text generation. We chose the applications' languages and feature sets based on the computing resources of target platforms, anticipated usage scenarios, and ease of application installation, deployment, and updating. Our primary results are the publication of the core source code implementing the LI-RADS algorithm and the availability of the applications for use worldwide via our website, http://www.liradsapp.com/. The Java application is free open-source software that can be integrated into nearly any vendor's reporting system. The iOS application is distributed through Apple's iTunes App Store. Observation categorizations of both programs have been manually validated to be correct. The iOS application has been used to characterize liver tumors during multidisciplinary conferences of our institution, and several faculty members, fellows, and residents have adopted the generated text of Java application into their diagnostic reports. Although these two applications were developed for the specific reporting requirements of our liver tumor service, we intend to apply this development model to other diseases as well. Through semiautomated structured report generation and observation characterization, we aim to improve patient care while increasing radiologist efficiency. Published by Elsevier Inc.

  11. Host Specificity in the Honeybee Parasitic Mite, Varroa spp. in Apis mellifera and Apis cerana.

    Directory of Open Access Journals (Sweden)

    Alexis L Beaurepaire

    Full Text Available The ectoparasitic mite Varroa destructor is a major global threat to the Western honeybee Apis mellifera. This mite was originally a parasite of A. cerana in Asia but managed to spill over into colonies of A. mellifera which had been introduced to this continent for honey production. To date, only two almost clonal types of V. destructor from Korea and Japan have been detected in A. mellifera colonies. However, since both A. mellifera and A. cerana colonies are kept in close proximity throughout Asia, not only new spill overs but also spill backs of highly virulent types may be possible, with unpredictable consequences for both honeybee species. We studied the dispersal and hybridisation potential of Varroa from sympatric colonies of the two hosts in Northern Vietnam and the Philippines using mitochondrial and microsatellite DNA markers. We found a very distinct mtDNA haplotype equally invading both A. mellifera and A. cerana in the Philippines. In contrast, we observed a complete reproductive isolation of various Vietnamese Varroa populations in A. mellifera and A. cerana colonies even if kept in the same apiaries. In light of this variance in host specificity, the adaptation of the mite to its hosts seems to have generated much more genetic diversity than previously recognised and the Varroa species complex may include substantial cryptic speciation.

  12. Changes in Alternative Splicing in Apis Mellifera Bees Fed Apis Cerana Royal Jelly

    Directory of Open Access Journals (Sweden)

    Shi Yuan Yuan

    2014-12-01

    Full Text Available The Western honey bee (Apis mellifera is a social insect characterized by caste differentiation in which the queen bee and worker bees display marked differences in morphology, behavior, reproduction, and longevity despite their identical genomes. The main causative factor in caste differentiation is the food fed to queen larvae, termed royal jelly (RJ. Alternative splicing (AS is an important RNA-mediated post-transcriptional process in eukaryotes. Here we report AS changes in A. mellifera after being fed either A. mellifera RJ or A. cerana RJ. The results demonstrated that the RJ type affected 4 types of AS in adult A. mellifera: exon skipping, intron retention, alternative 5’ splice sites, and alternative 3’splice sites. After feeding with A. cerana RJ, AS occurred in many genes in adult A. mellifera that encode proteins involved in development, growth, the tricarboxylic acid cycle, and substance metabolism. This study provides the first evidence that heterospecific RJ can influence the AS of many genes related to honey bee development and growth.

  13. Host Specificity in the Honeybee Parasitic Mite, Varroa spp. in Apis mellifera and Apis cerana.

    Science.gov (United States)

    Beaurepaire, Alexis L; Truong, Tuan A; Fajardo, Alejandro C; Dinh, Tam Q; Cervancia, Cleofas; Moritz, Robin F A

    2015-01-01

    The ectoparasitic mite Varroa destructor is a major global threat to the Western honeybee Apis mellifera. This mite was originally a parasite of A. cerana in Asia but managed to spill over into colonies of A. mellifera which had been introduced to this continent for honey production. To date, only two almost clonal types of V. destructor from Korea and Japan have been detected in A. mellifera colonies. However, since both A. mellifera and A. cerana colonies are kept in close proximity throughout Asia, not only new spill overs but also spill backs of highly virulent types may be possible, with unpredictable consequences for both honeybee species. We studied the dispersal and hybridisation potential of Varroa from sympatric colonies of the two hosts in Northern Vietnam and the Philippines using mitochondrial and microsatellite DNA markers. We found a very distinct mtDNA haplotype equally invading both A. mellifera and A. cerana in the Philippines. In contrast, we observed a complete reproductive isolation of various Vietnamese Varroa populations in A. mellifera and A. cerana colonies even if kept in the same apiaries. In light of this variance in host specificity, the adaptation of the mite to its hosts seems to have generated much more genetic diversity than previously recognised and the Varroa species complex may include substantial cryptic speciation.

  14. Codec-on-Demand Based on User-Level Virtualization

    Science.gov (United States)

    Zhang, Youhui; Zheng, Weimin

    At work, at home, and in some public places, a desktop PC is usually available nowadays. Therefore, it is important for users to be able to play various videos on different PCs smoothly, but the diversity of codec types complicates the situation. Although some mainstream media players can try to download the needed codec automatically, this may fail for average users because installing the codec usually requires administrator privileges to complete, while the user may not be the owner of the PC. We believe an ideal solution should work without users' intervention, and need no special privileges. This paper proposes such a user-friendly, program-transparent solution for Windows-based media players. It runs the media player in a user-mode virtualization environment, and then downloads the needed codec on-the-fly. Because of API (Application Programming Interface) interception, some resource-accessing API calls from the player will be redirected to the downloaded codec resources. Then from the viewpoint of the player, the necessary codec exists locally and it can handle the video smoothly, although neither system registry nor system folders was modified during this process. Besides convenience, the principle of least privilege is maintained and the host system is left clean. This paper completely analyzes the technical issues and presents such a prototype which can work with DirectShow-compatible players. Performance tests show that the overhead is negligible. Moreover, our solution conforms to the Software-As-A-Service (SaaS) mode, which is very promising in the Internet era.

  15. Data synchronisation and cost reduction using API in customer relationship management

    Directory of Open Access Journals (Sweden)

    Tomić Željko

    2016-01-01

    Full Text Available Research has shown that 51% of all ERP implementations involve some kind of problems in business operations during the 'go live' phase. Despite all the efforts to increase efficiency and improve business processes, many organizations come to a conclusion that once they move to the new ERP system they are not able to perform some of the basic business processes (both in the data migration phase and operational procedures, such as issuing goods from the warehouse. The ERP implementations are too often accompanied by technical and organizational issues that may cause problems in the functioning of a business system. As organizational issues are more frequently the cause of the problem, it is crucial to accurately perform the business processes analysis phase, as well as the final testing. Based on the analysis of the ERP (Enterprise Resource Planning, CRM (Customer Relationship Management and SCM (Supply Chain Management e-business models of the largest producers of software applications, the bottlenecks and shortcomings typical of the implementation of these models were identified in a select sample of clients and it has been established that there are certain inconsistencies and programme problems between the company information system (IS and the implemented ERP/CRM or SCM models. The identified problems served as the basis for designing and programming an application programming interface (API aimed at addressing certain application needs of the companies, i.e. the inadequate synchronization of databases and other IT resources. The API has been designed and programmed with a view to resolving the problems with inconsistencies and synchronization and reducing business operations costs. It has been tested as a pilot application on ISs of selected companies that apply the ERP/CRM business support systems. This work describes the ERP/CRM database synchronization process and tests the quality of the API solution based on a programmed web survey, i

  16. Determination of Bortezomib in API Samples Using HPLC: Assessment of Enantiomeric and Diastereomeric Impurities.

    Science.gov (United States)

    Kamalzadeh, Zahra; Babanezhad, Esmaeil; Ghaffari, Solmaz; Mohseni Ezhiyeh, Alireza; Mohammadnejad, Mahdieh; Naghibfar, Mehdi; Bararjanian, Morteza; Attar, Hossein

    2017-08-01

    A new, normal phase high performance liquid chromatography (NP-HPLC) method was developed for separation of Bortezomib (BZB) enantiomers and quantitative determination of (1S,2R)-enantiomer of BZB in active pharmaceutical ingredient (API) samples. The developed method was validated based on International Conference on Harmonisation (ICH) guidelines and it was proved to be accurate, precise and robust. The obtained resolution (RS) between the enantiomers was more than 2. The calibration curve for (1S,2R)-enantiomer was found to be linear in the concentration range of 0.24-5.36 mg/L with regression coefficient (R2) of 0.9998. Additionally, the limit of detection (LOD) and limit of quantification (LOQ) were 0.052 and 0.16 mg/L, respectively. Also, in this study, a precise, sensitive and robust gradient reversed-phase HPLC (RP-HPLC) method was developed and validated for determination of BZB in API samples. The detector response was linear over the concentration range of 0.26-1110.5 mg/L. The values of R2, LOD and LOQ were 0.9999, 0.084 and 0.25 mg/L, respectively. For both NP-HPLC and RP-HPLC methods, all of the RSD (%) values obtained in the precision study were 2,000 and RS > 2.0. The performance of two common integration methods of valley to valley and drop perpendicular for drawing the baseline between two adjacent peaks were investigated for the determination of diastereomeric impurity (Imp-D) in the BZB-API samples. The results showed that the valley to valley method outperform the drop perpendicular method for calculation of Imp-D peak areas. Therefore, valley to valley method was chosen for peak integration. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  17. MultiSpec: A Desktop and Online Geospatial Image Data Processing Tool

    Science.gov (United States)

    Biehl, L. L.; Hsu, W. K.; Maud, A. R. M.; Yeh, T. T.

    2017-12-01

    MultiSpec is an easy to learn and use, freeware image processing tool for interactively analyzing a broad spectrum of geospatial image data, with capabilities such as image display, unsupervised and supervised classification, feature extraction, feature enhancement, and several other functions. Originally developed for Macintosh and Windows desktop computers, it has a community of several thousand users worldwide, including researchers and educators, as a practical and robust solution for analyzing multispectral and hyperspectral remote sensing data in several different file formats. More recently MultiSpec was adapted to run in the HUBzero collaboration platform so that it can be used within a web browser, allowing new user communities to be engaged through science gateways. MultiSpec Online has also been extended to interoperate with other components (e.g., data management) in HUBzero through integration with the geospatial data building blocks (GABBs) project. This integration enables a user to directly launch MultiSpec Online from data that is stored and/or shared in a HUBzero gateway and to save output data from MultiSpec Online to hub storage, allowing data sharing and multi-step workflows without having to move data between different systems. MultiSpec has also been used in K-12 classes for which one example is the GLOBE program (www.globe.gov) and in outreach material such as that provided by the USGS (eros.usgs.gov/educational-activities). MultiSpec Online now provides teachers with another way to use MultiSpec without having to install the desktop tool. Recently MultiSpec Online was used in a geospatial data session with 30-35 middle school students at the Turned Onto Technology and Leadership (TOTAL) Camp in the summers of 2016 and 2017 at Purdue University. The students worked on a flood mapping exercise using Landsat 5 data to learn about land remote sensing using supervised classification techniques. Online documentation is available for Multi

  18. Antioxidant activity and irritation property of venoms from Apis species.

    Science.gov (United States)

    Somwongin, Suvimol; Chantawannakul, Panuwan; Chaiyana, Wantida

    2018-04-01

    Pharmacological effects of bee venom has been reported, however, it has been restricted to the bee venom collected from European honey bee (Apis mellifera). The aim of the present study was to compare the antioxidant activities and irritation properties of venoms collected from four different Apis species in Thailand, which includes Apis cerena (Asian cavity nesting honeybee), Apis florea (dwarf honeybee), Apis dorsata (giant honeybee), and A. mellifera. Melittin content of each bee venom extracts was investigated by using high-performance liquid chromatography. Ferric reducing antioxidant power, 2, 2'-azinobis (3-ethylbenzothiazoline-6-sulfonic acid), and 1, 1-diphenyl-2-picrylhydrazyl assay were used to determine the antioxidant activity, whereas, hen's egg test chorioallantoic membrane assay was used to determine the irritation property of each bee venom extracts. Melittin was the major constituent in all bee venom extracts. The melittin content in A. dorsata, A. mellifera, A. florea, and A. cerena were 95.8 ± 3.2%, 76.5 ± 1.9%, 66.3 ± 8.6%, and 56.8 ± 1.8%, respectively. Bee venom extract from A. dorsata possessed the highest antioxidant activity with the inhibition of 41.1 ± 2.2% against DPPH, Trolox equivalent antioxidant capacity of 10.21 ± 0.74 mM Trolox/mg and equivalent concentration (EC 1 ) of 0.35 ± 0.02 mM FeSO 4 /mg. Bee venom extract from A. mellifera exhibited the highest irritation, followed by A. cerena, A. dorsata, and A. florea, respectively. Melittin was the compound responsible for the irritation property of bee venom extracts since it could induce severe irritation (irritation score was 13.7 ± 0.5, at the concentration of 2 mg/ml). The extract from A. dorsata which possessed the highest antioxidant activity showed no irritation up to the concentration of 0.1 mg/ml. Therefore, bee venom extract from A. dorsata at the concentration not more than 0.1 mg/ml would be suggested for using

  19. Usability of Wearable and Desktop Game-Based Simulations: A Heuristic Evaluation

    Science.gov (United States)

    2010-05-01

    stretch, and people who play videogames will find the control scheme familiar. • Recommendation o Create as many “natural” controls as possible...change. o Needs work in both apps. o People should get better at playing videogames . In all seriousness a longer familiarization session may be

  20. Application and API for Real-time Visualization of Ground-motions and Tsunami

    Science.gov (United States)

    Aoi, S.; Kunugi, T.; Suzuki, W.; Kubo, T.; Nakamura, H.; Azuma, H.; Fujiwara, H.

    2015-12-01

    Due to the recent progress of seismograph and communication environment, real-time and continuous ground-motion observation becomes technically and economically feasible. K-NET and KiK-net, which are nationwide strong motion networks operated by NIED, cover all Japan by about 1750 stations in total. More than half of the stations transmit the ground-motion indexes and/or waveform data in every second. Traditionally, strong-motion data were recorded by event-triggering based instruments with non-continues telephone line which is connected only after an earthquake. Though the data from such networks mainly contribute to preparations for future earthquakes, huge amount of real-time data from dense network are expected to directly contribute to the mitigation of ongoing earthquake disasters through, e.g., automatic shutdown plants and helping decision-making for initial response. By generating the distribution map of these indexes and uploading them to the website, we implemented the real-time ground motion monitoring system, Kyoshin (strong-motion in Japanese) monitor. This web service (www.kyoshin.bosai.go.jp) started in 2008 and anyone can grasp the current ground motions of Japan. Though this service provides only ground-motion map in GIF format, to take full advantage of real-time strong-motion data to mitigate the ongoing disasters, digital data are important. We have developed a WebAPI to provide real-time data and related information such as ground motions (5 km-mesh) and arrival times estimated from EEW (earthquake early warning). All response data from this WebAPI are in JSON format and are easy to parse. We also developed Kyoshin monitor application for smartphone, 'Kmoni view' using the API. In this application, ground motions estimated from EEW are overlapped on the map with the observed one-second-interval indexes. The application can playback previous earthquakes for demonstration or disaster drill. In mobile environment, data traffic and battery are

  1. Fast Deployment on the Cloud of Integrated Postgres, API and a Jupyter Notebook for Geospatial Collaboration

    Science.gov (United States)

    Fatland, R.; Tan, A.; Arendt, A. A.

    2016-12-01

    We describe a Python-based implementation of a PostgreSQL database accessed through an Application Programming Interface (API) hosted on the Amazon Web Services public cloud. The data is geospatial and concerns hydrological model results in the glaciated catchment basins of southcentral and southeast Alaska. This implementation, however, is intended to be generalized to other forms of geophysical data, particularly data that is intended to be shared across a collaborative team or publicly. An example (moderate-size) dataset is provided together with the code base and a complete installation tutorial on GitHub. An enthusiastic scientist with some familiarity with software installation can replicate the example system in two hours. This installation includes database, API, a test Client and a supporting Jupyter Notebook, specifically oriented towards Python 3 and markup text to comprise an executable paper. The installation 'on the cloud' often engenders discussion and consideration of cloud cost and safety. By treating the process as somewhat "cookbook" we hope to first demonstrate the feasibility of the proposition. A discussion of cost and data security is provided in this presentation and in the accompanying tutorial/documentation. This geospatial data system case study is part of a larger effort at the University of Washington to enable research teams to take advantage of the public cloud to meet challenges in data management and analysis.

  2. Infra-Population and -Community Dynamics of the Parasites Nosema apis and Nosema ceranae, and Consequences for Honey Bee (Apis mellifera) Hosts

    Science.gov (United States)

    Williams, Geoffrey R.; Shutler, Dave; Burgher-MacLellan, Karen L.; Rogers, Richard E. L.

    2014-01-01

    Nosema spp. fungal gut parasites are among myriad possible explanations for contemporary increased mortality of western honey bees (Apis mellifera, hereafter honey bee) in many regions of the world. Invasive Nosema ceranae is particularly worrisome because some evidence suggests it has greater virulence than its congener N. apis. N. ceranae appears to have recently switched hosts from Asian honey bees (Apis cerana) and now has a nearly global distribution in honey bees, apparently displacing N. apis. We examined parasite reproduction and effects of N. apis, N. ceranae, and mixed Nosema infections on honey bee hosts in laboratory experiments. Both infection intensity and honey bee mortality were significantly greater for N. ceranae than for N. apis or mixed infections; mixed infection resulted in mortality similar to N. apis parasitism and reduced spore intensity, possibly due to inter-specific competition. This is the first long-term laboratory study to demonstrate lethal consequences of N. apis and N. ceranae and mixed Nosema parasitism in honey bees, and suggests that differences in reproduction and intra-host competition may explain apparent heterogeneous exclusion of the historic parasite by the invasive species. PMID:24987989

  3. AS COMPOSIÇÕES DA ESCUTA E A INTERNET: OS DJ'S DE DESKTOP

    Directory of Open Access Journals (Sweden)

    Rodrigo Fonseca e Rodrigues

    2006-12-01

    Full Text Available O texto aborda questões emergentes das ocasiões de experiência que, ativadas pelo uso idiossincrático das máquinas em rede, passam a contagiar circunstâncias e práticas genuínas de composição musical, bem como de outras disposições da escuta. Isto se passa quando os "dj's produtores de desktop" remodulam forças latentes nos enunciados musicais da cultura corporativa para revelarem, a partir da prática do remix, outros eventos, instaurando regimes singulares para a sensação. Seria preciso pensar tais poéticas da escuta em rede como implicações conjuntas de conexões não apenas de materiais musicais, mas também de universos incorporais, de forças insonoras, amparando-se, para tanto, nas direções conceituais deleuzianas acerca das questões do virtual e do acontecimento na sensação musical.

  4. A novel desktop device for lapping thin-walled micro groove

    Science.gov (United States)

    Wang, Shilei; Wang, Bo; Che, Lin; Ding, Fei; Li, Duo

    2014-08-01

    This paper presents a novel desktop device for lapping thin-walled micro groove of a specimen used in optical equipment, the device is aimed to remove metamorphic layer (about 1μm thick) formed on the groove's upper surface as well as ensure its thickness accuracy. It adopts the way of macro/micro motion combination, the macro-motion table uses stepper motor and ball screws to realize motion in large stroke, high speed and the micron level positioning, the micro-motion table uses the electrostriction appliance to actuate the flexible four bars mechanism to realize the small stroke, low speed, and the submicron level positioning. The system uses the strategy of two ways of feedback, the macro/micro motion table uses the precise linear grating as close-loop position feedback, and the sensing holder uses the eddy current transducer as the force and deformation feedback of the elastic fixture. The most novel aspect is the first proposed idea of realizing automatic feeding by elastic recovery of the fixture, whose structure has been delicately designed. In order to ensure small lapping force and relatively high natural frequency, both static and modal analysis of the fixture has been done by ANSYS, the results was in good accordance with experiments. Lapping experiments have showed that this device can remove metamorphic layer efficiently as well as obtain good surface quality at the same time.

  5. Prototype Implementation of Web and Desktop Applications for ALMA Science Verification Data and the Lessons Learned

    Science.gov (United States)

    Eguchi, S.; Kawasaki, W.; Shirasaki, Y.; Komiya, Y.; Kosugi, G.; Ohishi, M.; Mizumoto, Y.

    2013-10-01

    ALMA is estimated to generate TB scale data during only one observation; astronomers need to identify which part of the data they are really interested in. We have been developing new GUI software for this purpose utilizing the VO interface: ALMA Web Quick Look System (ALMAWebQL) and ALMA Desktop Application (Vissage). The former is written in JavaScript and HTML5 generated from Java code by the Google Web Toolkit, and the latter is in pure Java. An essential point of our approach is how to reduce network traffic: we prepare, in advance, “compressed” FITS files of 2x2x1 (horizontal, vertical, and spectral directions, respectively) binning, 2 x 2 x 2 binning, 4 x 4 x 2 binning data, and so on. These files are hidden from users, and Web QL automatically chooses the proper one for each user operation. Through this work, we find that network traffic in our system is still a bottleneck towards TB scale data distribution. Hence we have to develop alternative data containers for much faster data processing. In this paper, we introduce our data analysis systems, and describe what we learned through the development.

  6. A Unified Algorithm for Virtual Desktops Placement in Distributed Cloud Computing

    Directory of Open Access Journals (Sweden)

    Jiangtao Zhang

    2016-01-01

    Full Text Available Distributed cloud has been widely adopted to support service requests from dispersed regions, especially for large enterprise which requests virtual desktops for multiple geodistributed branch companies. The cloud service provider (CSP aims to deliver satisfactory services at the least cost. CSP selects proper data centers (DCs closer to the branch companies so as to shorten the response time to user request. At the same time, it also strives to cut cost considering both DC level and server level. At DC level, the expensive long distance inter-DC bandwidth consumption should be reduced and lower electricity price is sought. Inside each tree-like DC, servers are trying to be used as little as possible so as to save equipment cost and power. In nature, there is a noncooperative relation between the DC level and server level in the selection. To attain these objectives and capture the noncooperative relation, multiobjective bilevel programming is used to formulate the problem. Then a unified genetic algorithm is proposed to solve the problem which realizes the selection of DC and server simultaneously. The extensive simulation shows that the proposed algorithm outperforms baseline algorithm in both quality of service guaranteeing and cost saving.

  7. Deep Unsupervised Learning on a Desktop PC: A Primer for Cognitive Scientists

    Science.gov (United States)

    Testolin, Alberto; Stoianov, Ivilin; De Filippo De Grazia, Michele; Zorzi, Marco

    2013-01-01

    Deep belief networks hold great promise for the simulation of human cognition because they show how structured and abstract representations may emerge from probabilistic unsupervised learning. These networks build a hierarchy of progressively more complex distributed representations of the sensory data by fitting a hierarchical generative model. However, learning in deep networks typically requires big datasets and it can involve millions of connection weights, which implies that simulations on standard computers are unfeasible. Developing realistic, medium-to-large-scale learning models of cognition would therefore seem to require expertise in programing parallel-computing hardware, and this might explain why the use of this promising approach is still largely confined to the machine learning community. Here we show how simulations of deep unsupervised learning can be easily performed on a desktop PC by exploiting the processors of low cost graphic cards (graphic processor units) without any specific programing effort, thanks to the use of high-level programming routines (available in MATLAB or Python). We also show that even an entry-level graphic card can outperform a small high-performance computing cluster in terms of learning time and with no loss of learning quality. We therefore conclude that graphic card implementations pave the way for a widespread use of deep learning among cognitive scientists for modeling cognition and behavior. PMID:23653617

  8. MD Simulations of Viruslike Particles with Supra CG Solvation Affordable to Desktop Computers.

    Science.gov (United States)

    Machado, Matı As R; González, Humberto C; Pantano, Sergio

    2017-10-10

    Viruses are tremendously efficient molecular devices that optimize the packing of genetic material using a minimalistic number of proteins to form a capsid or envelope that protects them from external threats, being also part of cell recognition, fusion, and budding machineries. Progress in experimental techniques has provided a large number of high-resolution structures of viruses and viruslike particles (VLP), while molecular dynamics simulations may furnish lively and complementary insights on the fundamental forces ruling viral assembly, stability, and dynamics. However, the large size and complexity of these macromolecular assemblies pose significant computational challenges. Alternatively, Coarse-Grained (CG) methods, which resign atomistic resolution privileging computational efficiency, can be used to characterize the dynamics of VLPs. Still, the massive amount of solvent present in empty capsids or envelopes suggests that hybrid schemes keeping a higher resolution on regions of interest (i.e., the viral proteins and their surroundings) and a progressively coarser description on the bulk may further improve efficiency. Here we introduce a mesoscale explicit water model to be used in double- or triple-scale simulations in combination with popular atomistic parameters and the CG water used by the SIRAH force field. Simulations performed on VLPs of different sizes, along with a comprehensive analysis of the PDB, indicate that most of the VLPs so far reported are amenable to be handled on a GPU-accelerated desktop computer using this simulation scheme.

  9. Correleation of the SAGE III on ISS Thermal Models in Thermal Desktop

    Science.gov (United States)

    Amundsen, Ruth M.; Davis, Warren T.; Liles, Kaitlin, A. K.; McLeod, Shawn C.

    2017-01-01

    The Stratospheric Aerosol and Gas Experiment III (SAGE III) instrument is the fifth in a series of instruments developed for monitoring aerosols and gaseous constituents in the stratosphere and troposphere. SAGE III was launched on February 19, 2017 and mounted to the International Space Station (ISS) to begin its three-year mission. A detailed thermal model of the SAGE III payload, which consists of multiple subsystems, has been developed in Thermal Desktop (TD). Correlation of the thermal model is important since the payload will be expected to survive a three-year mission on ISS under varying thermal environments. Three major thermal vacuum (TVAC) tests were completed during the development of the SAGE III Instrument Payload (IP); two subsystem-level tests and a payload-level test. Additionally, a characterization TVAC test was performed in order to verify performance of a system of heater plates that was designed to allow the IP to achieve the required temperatures during payload-level testing; model correlation was performed for this test configuration as well as those including the SAGE III flight hardware. This document presents the methods that were used to correlate the SAGE III models to TVAC at the subsystem and IP level, including the approach for modeling the parts of the payload in the thermal chamber, generating pre-test predictions, and making adjustments to the model to align predictions with temperatures observed during testing. Model correlation quality will be presented and discussed, and lessons learned during the correlation process will be shared.

  10. Generation of orientation tools for automated zebrafish screening assays using desktop 3D printing.

    Science.gov (United States)

    Wittbrodt, Jonas N; Liebel, Urban; Gehrig, Jochen

    2014-05-01

    The zebrafish has been established as the main vertebrate model system for whole organism screening applications. However, the lack of consistent positioning of zebrafish embryos within wells of microtiter plates remains an obstacle for the comparative analysis of images acquired in automated screening assays. While technical solutions to the orientation problem exist, dissemination is often hindered by the lack of simple and inexpensive ways of distributing and duplicating tools. Here, we provide a cost effective method for the production of 96-well plate compatible zebrafish orientation tools using a desktop 3D printer. The printed tools enable the positioning and orientation of zebrafish embryos within cavities formed in agarose. Their applicability is demonstrated by acquiring lateral and dorsal views of zebrafish embryos arrayed within microtiter plates using an automated screening microscope. This enables the consistent visualization of morphological phenotypes and reporter gene expression patterns. The designs are refined versions of previously demonstrated devices with added functionality and strongly reduced production costs. All corresponding 3D models are freely available and digital design can be easily shared electronically. In combination with the increasingly widespread usage of 3D printers, this provides access to the developed tools to a wide range of zebrafish users. Finally, the design files can serve as templates for other additive and subtractive fabrication methods.

  11. Deep Unsupervised Learning on a Desktop PC: A Primer for Cognitive Scientists.

    Science.gov (United States)

    Testolin, Alberto; Stoianov, Ivilin; De Filippo De Grazia, Michele; Zorzi, Marco

    2013-01-01

    Deep belief networks hold great promise for the simulation of human cognition because they show how structured and abstract representations may emerge from probabilistic unsupervised learning. These networks build a hierarchy of progressively more complex distributed representations of the sensory data by fitting a hierarchical generative model. However, learning in deep networks typically requires big datasets and it can involve millions of connection weights, which implies that simulations on standard computers are unfeasible. Developing realistic, medium-to-large-scale learning models of cognition would therefore seem to require expertise in programing parallel-computing hardware, and this might explain why the use of this promising approach is still largely confined to the machine learning community. Here we show how simulations of deep unsupervised learning can be easily performed on a desktop PC by exploiting the processors of low cost graphic cards (graphic processor units) without any specific programing effort, thanks to the use of high-level programming routines (available in MATLAB or Python). We also show that even an entry-level graphic card can outperform a small high-performance computing cluster in terms of learning time and with no loss of learning quality. We therefore conclude that graphic card implementations pave the way for a widespread use of deep learning among cognitive scientists for modeling cognition and behavior.

  12. Deep unsupervised learning on a desktop PC: A primer for cognitive scientists

    Directory of Open Access Journals (Sweden)

    Alberto eTestolin

    2013-05-01

    Full Text Available Deep belief networks hold great promise for the simulation of human cognition because they show how structured and abstract representations may emerge from probabilistic unsupervised learning. These networks build a hierarchy of progressively more complex distributed representations of the sensory data by fitting a hierarchical generative model. However, learning in deep networks typically requires big datasets and it can involve millions of connection weights, which implies that simulations on standard computers are unfeasible. Developing realistic, medium-to-large-scale learning models of cognition would therefore seem to require expertise in programming parallel-computing hardware, and this might explain why the use of this promising approach is still largely confined to the machine learning community. Here we show how simulations of deep unsupervised learning can be easily performed on a desktop PC by exploiting the processors of low-cost graphic cards (GPUs without any specific programming effort, thanks to the use of high-level programming routines (available in MATLAB or Python. We also show that even an entry-level graphic card can outperform a small high-performance computing cluster in terms of learning time and with no loss of learning quality. We therefore conclude that graphic card implementations pave the way for a widespread use of deep learning among cognitive scientists for modeling cognition and behavior.

  13. VRLane: a desktop virtual safety management program for underground coal mine

    Science.gov (United States)

    Li, Mei; Chen, Jingzhu; Xiong, Wei; Zhang, Pengpeng; Wu, Daozheng

    2008-10-01

    VR technologies, which generate immersive, interactive, and three-dimensional (3D) environments, are seldom applied to coal mine safety work management. In this paper, a new method that combined the VR technologies with underground mine safety management system was explored. A desktop virtual safety management program for underground coal mine, called VRLane, was developed. The paper mainly concerned about the current research advance in VR, system design, key techniques and system application. Two important techniques were introduced in the paper. Firstly, an algorithm was designed and implemented, with which the 3D laneway models and equipment models can be built on the basis of the latest mine 2D drawings automatically, whereas common VR programs established 3D environment by using 3DS Max or the other 3D modeling software packages with which laneway models were built manually and laboriously. Secondly, VRLane realized system integration with underground industrial automation. VRLane not only described a realistic 3D laneway environment, but also described the status of the coal mining, with functions of displaying the run states and related parameters of equipment, per-alarming the abnormal mining events, and animating mine cars, mine workers, or long-wall shearers. The system, with advantages of cheap, dynamic, easy to maintenance, provided a useful tool for safety production management in coal mine.

  14. A desktop system of virtual morphometric globes for Mars and the Moon

    Science.gov (United States)

    Florinsky, I. V.; Filippov, S. V.

    2017-03-01

    Global morphometric models can be useful for earth and planetary studies. Virtual globes - programs implementing interactive three-dimensional (3D) models of planets - are increasingly used in geo- and planetary sciences. We describe the development of a desktop system of virtual morphometric globes for Mars and the Moon. As the initial data, we used 15'-gridded global digital elevation models (DEMs) extracted from the Mars Orbiter Laser Altimeter (MOLA) and the Lunar Orbiter Laser Altimeter (LOLA) gridded archives. For two celestial bodies, we derived global digital models of several morphometric attributes, such as horizontal curvature, vertical curvature, minimal curvature, maximal curvature, and catchment area. To develop the system, we used Blender, the free open-source software for 3D modeling and visualization. First, a 3D sphere model was generated. Second, the global morphometric maps were imposed to the sphere surface as textures. Finally, the real-time 3D graphics Blender engine was used to implement rotation and zooming of the globes. The testing of the developed system demonstrated its good performance. Morphometric globes clearly represent peculiarities of planetary topography, according to the physical and mathematical sense of a particular morphometric variable.

  15. Desktop Software for Patch-Clamp Raw Binary Data Conversion and Preprocessing

    Directory of Open Access Journals (Sweden)

    Ning Zhang

    2011-01-01

    Full Text Available Since raw data recorded by patch-clamp systems are always stored in binary format, electrophysiologists may experience difficulties with patch clamp data preprocessing especially when they want to analyze by custom-designed algorithms. In this study, we present desktop software, called PCDReader, which could be an effective and convenient solution for patch clamp data preprocessing for daily laboratory use. We designed a novel class module, called clsPulseData, to directly read the raw data along with the parameters recorded from HEKA instruments without any other program support. By a graphical user interface, raw binary data files can be converted into several kinds of ASCII text files for further analysis, with several preprocessing options. And the parameters can also be viewed, modified and exported into ASCII files by a user-friendly Explorer style window. The real-time data loading technique and optimized memory management programming makes PCDReader a fast and efficient tool. The compiled software along with the source code of the clsPulseData class module is freely available to academic and nonprofit users.

  16. Uncovering the immune responses of Apis mellifera ligustica larval gut to Ascosphaera apis infection utilizing transcriptome sequencing.

    Science.gov (United States)

    Chen, Dafu; Guo, Rui; Xu, Xijian; Xiong, Cuiling; Liang, Qin; Zheng, Yanzhen; Luo, Qun; Zhang, Zhaonan; Huang, Zhijian; Kumar, Dhiraj; Xi, Weijun; Zou, Xuan; Liu, Min

    2017-07-20

    Honeybees are susceptible to a variety of diseases, including chalkbrood, which is capable of causing huge losses of both the number of bees and colony productivity. This research is designed to characterize the transcriptome profiles of Ascosphaera apis-treated and un-treated larval guts of Apis mellifera ligustica in an attempt to unravel the molecular mechanism underlying the immune responses of western honeybee larval guts to mycosis. In this study, 24, 296 and 2157 genes were observed to be differentially expressed in A. apis-treated Apis mellifera (4-, 5- and 6-day-old) compared with un-treated larval guts. Moreover, the expression patterns of differentially expressed genes (DEGs) were examined via trend analysis, and subsequently, gene ontology analysis and KEGG pathway enrichment analysis were conducted for DEGs involved in up- and down-regulated profiles. Immunity-related pathways were selected for further analysis, and our results demonstrated that a total of 13 and 50 DEGs were annotated in the humoral immune-related and cellular immune-related pathways, respectively. Additionally, we observed that many DEGs up-regulated in treated guts were part of cellular immune pathways, such as the lysosome, ubiquitin mediated proteolysis, and insect hormone biosynthesis pathways and were induced by A. apis invasion. However, more down-regulated DEGs were restrained. Surprisingly, a majority of DEGs within the Toll-like receptor signaling pathway, and the MAPK signaling pathway were up-regulated in treated guts, while all but two genes involved in the NF-κB signaling pathway were down-regulated, which suggested that most genes involved in humoral immune-related pathways were activated in response to the invasive fungal pathogen. This study's findings provide valuable information regarding the investigation of the molecular mechanism of immunity defenses of A. m. ligustica larval guts to infection with A. apis. Furthermore, these studies lay the groundwork for

  17. Pertukaran Data Antar Database Dengan Menggunakan Teknologi API

    Directory of Open Access Journals (Sweden)

    Ahmad Hanafi

    2017-03-01

    Full Text Available Electronically data interchange between institutions or companies must be supported with appropriate data storage media capacity. MySQL is a database engine that is used to perform data storage in the form of information, where the data can be utilized as needed. MYSQL has the advantage of which is to provide convenience in terms of usage, and able to work on different platforms. System requirements that must be reliable and multitasking capable of making the database not only as a data storage medium, but can also be utilized as a means of data exchange. Dropbox API is the best solution that can be utilized as a technology that supports the database to be able to Exchange data. The combination of the Dropbox API and database can be used as a very cheap solution for small companies to implement data exchange, because it only requires a relatively small Internet connection.

  18. QSPIN: A High Level Java API for Quantum Computing Experimentation

    Science.gov (United States)

    Barth, Tim

    2017-01-01

    QSPIN is a high level Java language API for experimentation in QC models used in the calculation of Ising spin glass ground states and related quadratic unconstrained binary optimization (QUBO) problems. The Java API is intended to facilitate research in advanced QC algorithms such as hybrid quantum-classical solvers, automatic selection of constraint and optimization parameters, and techniques for the correction and mitigation of model and solution errors. QSPIN includes high level solver objects tailored to the D-Wave quantum annealing architecture that implement hybrid quantum-classical algorithms [Booth et al.] for solving large problems on small quantum devices, elimination of variables via roof duality, and classical computing optimization methods such as GPU accelerated simulated annealing and tabu search for comparison. A test suite of documented NP-complete applications ranging from graph coloring, covering, and partitioning to integer programming and scheduling are provided to demonstrate current capabilities.

  19. Standard methods for toxicology research in Apis mellifera

    OpenAIRE

    Giffard, Hervé; Aupinel, Pierrick; Belzunces, Luc; Chauzat, Marie-Pierre; Claßen, Christian; Colin, Marc E.; Dupont, Thierry; Girolami, Vincenzo; Johnson, Reed; Le Conte, Yves; Lückmann, Johannes; Marzaro, Matteo; Pistorius, Jens; Porrini, Claudio; Schur, Andrea

    2013-01-01

    Modern agriculture often involves the use of pesticides to protect crops. These substances are harmful to target organisms (pests and pathogens). Nevertheless, they can also damage non-target animals, such as pollinators and entomophagous arthropods. It is obvious that the undesirable side effects of pesticides on the environment should be reduced to a minimum. Western honey bees (Apis mellifera) are very important organisms from an agricultural perspective and are vulnerable to pesticide-ind...

  20. Does It Matter Whether One Takes a Test on an iPad or a Desktop Computer?

    Science.gov (United States)

    Ling, Guangming

    2016-01-01

    To investigate possible iPad related mode effect, we tested 403 8th graders in Indiana, Maryland, and New Jersey under three mode conditions through random assignment: a desktop computer, an iPad alone, and an iPad with an external keyboard. All students had used an iPad or computer for six months or longer. The 2-hour test included reading, math,…

  1. Do small fish mean no voucher? Using a flatbed desktop scanner to document larval and small specimens before destructive analyses

    Czech Academy of Sciences Publication Activity Database

    Kalous, L.; Šlechtová, Věra; Petrtýl, M.; Kohout, Jan; Čech, Martin

    2010-01-01

    Roč. 26, č. 4 (2010), s. 614-617 ISSN 0175-8659 R&D Projects: GA ČR GA206/06/1371; GA ČR GP206/09/P266 Institutional research plan: CEZ:AV0Z50450515; CEZ:AV0Z60170517 Keywords : small fish * voucher * desktop scanner Subject RIV: GL - Fishing Impact factor: 0.945, year: 2010

  2. Twin-Wire Pulsed Tandem Gas Metal Arc Welding of API X80 Steel Linepipe

    Directory of Open Access Journals (Sweden)

    Wenhao Wu

    2018-01-01

    Full Text Available Twin-Wire Pulsed Tandem Gas Metal Arc Welding process with high welding production efficiency was used to join the girth weld seam of API X80 steel linepipe of 18.4 mm wall thickness and 1422 mm diameter. The macrostructure, microstructure, hardness, and electrochemical corrosion behavior of welded joints were studied. Effects of temperature and Cl− concentration on the corrosion behavior of base metal and weld metal were investigated. Results show that the welded joint has good morphology, mechanical properties, and corrosion resistance. The corrosion resistance of both the base metal and the weld metal decreases with increasing temperature or Cl− concentration. In the solution with high Cl− concentration, the base metal and weld metal are more susceptible to pitting. The corrosion resistance of the weld metal is slightly lower than that of the base metal.

  3. Carbonic anhydrase from Apis mellifera: purification and inhibition by pesticides.

    Science.gov (United States)

    Soydan, Ercan; Güler, Ahmet; Bıyık, Selim; Şentürk, Murat; Supuran, Claudiu T; Ekinci, Deniz

    2017-12-01

    Carbonic anhydrase (CA) enzymes have been shown to play an important role in ion transport and in pH regulation in several organisms. Despite this information and the wealth of knowledge regarding the significance of CA enzymes, few studies have been reported about bee CA enzymes and the hazardous effects of chemicals. Using Apis mellifera as a model, this study aimed to determine the risk of pesticides on Apis mellifera Carbonic anhydrase enzyme (Am CA). CA was initially purified from Apis mellifera spermatheca for the first time in the literature. The enzyme was purified with an overall purification of ∼35-fold with a molecular weight of ∼32 kDa. The enzyme was then exposed to pesticides, including tebuconazole, propoxur, carbaryl, carbofuran, simazine and atrazine. The six pesticides dose-dependently inhibited in vitro AmCA activity at low micromolar concentrations. IC 50 values for the pesticides were 0.0030, 0.0321, 0.0031, 0.0087, 0.0273 and 0.0165 μM, respectively. The AmCA inhibition mechanism of these compounds is unknown at this moment.

  4. Variation morphogeometrics of Africanized honey bees (Apis mellifera in Brazil

    Directory of Open Access Journals (Sweden)

    Lorena A. Nunes

    2012-09-01

    Full Text Available The morphometrics of the honey bee Apis mellifera L., 1758 has been widely studied mainly because this species has great ecological importance, high adaptation capacity, wide distribution and capacity to effectively adapt to different regions. The current study aimed to investigate the morphometric variations of wings and pollen baskets of honey bees Apis mellifera scutellata Lepeletier, 1836 from the five regions in Brazil. We used geometric morphometrics to identify the existence of patterns of variations of shape and size in Africanized honey bees in Brazil 16 years after the classic study with this species, allowing a temporal and spatial comparative analysis using new technological resources to assess morphometrical data. Samples were collected in 14 locations in Brazil, covering the five geographical regions of the country. The shape analysis and multivariate analyses of the wing allowed to observe that there is a geographical pattern among the population of Apis mellifera in Brazil. The geographical variations may be attributed to the large territorial extension of the country in addition to the differences between the bioregions.

  5. ADS 2.0: New Architecture, API and Services

    Science.gov (United States)

    Chyla, R.; Accomazzi, A.; Holachek, A.; Grant, C. S.; Elliott, J.; Henneken, E. A.; Thompson, D. M.; Kurtz, M. J.; Murray, S. S.; Sudilovsky, V.

    2015-09-01

    The ADS platform is undergoing the biggest rewrite of its 20-year history. While several components have been added to its architecture over the past couple of years, this talk will concentrate on the underpinnings of ADS's search layer and its API. To illustrate the design of the components in the new system, we will show how the new ADS user interface is built exclusively on top of the API using RESTful web services. Taking one step further, we will discuss how we plan to expose the treasure trove of information hosted by ADS (10 million records and fulltext for much of the Astronomy and Physics refereed literature) to partners interested in using this API. This will provide you (and your intelligent applications) with access to ADS's underlying data to enable the extraction of new knowledge and the ingestion of these results back into the ADS. Using this framework, researchers could run controlled experiments with content extraction, machine learning, natural language processing, etc. In this talk, we will discuss what is already implemented, what will be available soon, and where we are going next.

  6. Scientific Opinion on the science behind the development of a risk assessment of Plant Protection Products on bees (Apis mellifera, Bombus spp. and solitary bees)

    NARCIS (Netherlands)

    Luttik, R.; Arnold, G.; Boesten, J.J.T.I.; Cresswell, J.; Hart, A.; Pistorius, J.; Sgolastra, F.; Delso, N.S.; Steurbaut, W.; Thompson, H.

    2012-01-01

    The PPR Panel was asked to deliver a scientific opinion on the science behind the development of a risk assessment of plant protection products on bees (Apis mellifera, Bombus spp. and solitary bees). Specific protection goals options were suggested based on the ecosystem services approach. The

  7. Improving the API dissolution rate during pharmaceutical hot-melt extrusion I: Effect of the API particle size, and the co-rotating, twin-screw extruder screw configuration on the API dissolution rate.

    Science.gov (United States)

    Li, Meng; Gogos, Costas G; Ioannidis, Nicolas

    2015-01-15

    The dissolution rate of the active pharmaceutical ingredients in pharmaceutical hot-melt extrusion is the most critical elementary step during the extrusion of amorphous solid solutions - total dissolution has to be achieved within the short residence time in the extruder. Dissolution and dissolution rates are affected by process, material and equipment variables. In this work, we examine the effect of one of the material variables and one of the equipment variables, namely, the API particle size and extruder screw configuration on the API dissolution rate, in a co-rotating, twin-screw extruder. By rapidly removing the extruder screws from the barrel after achieving a steady state, we collected samples along the length of the extruder screws that were characterized by polarized optical microscopy (POM) and differential scanning calorimetry (DSC) to determine the amount of undissolved API. Analyses of samples indicate that reduction of particle size of the API and appropriate selection of screw design can markedly improve the dissolution rate of the API during extrusion. In addition, angle of repose measurements and light microscopy images show that the reduction of particle size of the API can improve the flowability of the physical mixture feed and the adhesiveness between its components, respectively, through dry coating of the polymer particles by the API particles. Copyright © 2014. Published by Elsevier B.V.

  8. The end of polling: why and how to transform a REST API into a Data Streaming API?

    CERN Multimedia

    CERN. Geneva

    2017-01-01

    We know interactivity is the key to keep our user’s interest alive but we can’t reduce animation to UI anymore. Twitter, Waze, Slack… users are used to have real-time data in applications they love. But how can you turn your static API into a stream of data? By pulling? Pushing? Webhook-ing? When talking about data streaming, we often think about WebSockets. But have you ever heard of Server-Sent Events? In this tools-in-action we will compare those technologies to understand which one you should opt for depending on your usecase, and I’ll show you how we have been reducing the amount of data to transfer even further with JSON-Patch. And because real-time data is not only needed by web (and because it’s much more fun), I’ll show you how we can make a drone dance on streamed APIs.

  9. Modular and scalable RESTful API to sustain STAR collaboration's record keeping

    Science.gov (United States)

    Arkhipkin, D.; Lauret, J.; Shanmuganathan, P. V.

    2015-12-01

    STAR collaboration's record system is a collection of heterogeneous and sparse information associated to each members and institutions. In its original incarnation, only flat information was stored revealing many restrictions such as the lack of historical change information, the inability to keep track of members leaving and re-joining STAR, or the ability to easily extend the saved information as new requirements appeared. In mid-2013, a new project was launched covering an extensive set of revisited requirements. The requirements led us to a design based on a RESTful API, back-end storage engine relying on key/value pair data representation model coupled with a tiered architecture design. This design was motivated by the fact that unifying many STAR tools, relying on the same business logic and storage engine, was a key and central feature for the maintainability and presentation of records. This central service API would leave no ambiguities and provide easy service integration between STAR tools. The new design stores the changes in records dynamically and allows tracking the changes chronologically. The storage engine is extensible as new field of information emerges (member specific or general) without affecting the presentation or the business logic layers. The new record system features a convenient administrative interface, fuzzy algorithms for data entry and search, and provides basic statistics and graphs. Finally, this modular approach is supplemented with access control, allowing private information and administrative operations to be hidden away from public eyes.

  10. On Parallelizing Single Dynamic Simulation Using HPC Techniques and APIs of Commercial Software

    Energy Technology Data Exchange (ETDEWEB)

    Diao, Ruisheng; Jin, Shuangshuang; Howell, Frederic; Huang, Zhenyu; Wang, Lei; Wu, Di; Chen, Yousu

    2017-05-01

    Time-domain simulations are heavily used in today’s planning and operation practices to assess power system transient stability and post-transient voltage/frequency profiles following severe contingencies to comply with industry standards. Because of the increased modeling complexity, it is several times slower than real time for state-of-the-art commercial packages to complete a dynamic simulation for a large-scale model. With the growing stochastic behavior introduced by emerging technologies, power industry has seen a growing need for performing security assessment in real time. This paper presents a parallel implementation framework to speed up a single dynamic simulation by leveraging the existing stability model library in commercial tools through their application programming interfaces (APIs). Several high performance computing (HPC) techniques are explored such as parallelizing the calculation of generator current injection, identifying fast linear solvers for network solution, and parallelizing data outputs when interacting with APIs in the commercial package, TSAT. The proposed method has been tested on a WECC planning base case with detailed synchronous generator models and exhibits outstanding scalable performance with sufficient accuracy.

  11. Dispositivos móveis e APIs na construção do Jornalismo Hiperlocal

    Directory of Open Access Journals (Sweden)

    Walter Teixeira Lima Junior

    2016-08-01

    Full Text Available Este trabalho tem como objetivo discutir a introdução de tecnologias digitais conectadas baseadas em Application Programming Interface (API, que permite a emergência de novas formas de distribuição da informação jornalística tendo como base a informação geográfica (localização gerada por intermédio de uma plataforma de comunicação móvel. Essa arquitetura tecnológica torna-se possível devido à informação ser relacionada e correlacionada por intermédio de APIs. Elas estão interligadas através de pontes de metadados, criando inúmeras possibilidades de camadas informativas. Essa abordagem permite oferecer informação local por tecnologias baseadas em localização, consequentemente expandindo o conceito tradicional de Hiperlocal.

  12. Federal Procurement Data System - FAADS API

    Data.gov (United States)

    General Services Administration — The Federal Award Assistance Data System (FAADS) has been re-engineered as a real-time federal enterprise information system. Web services based on SOAP and XML,...

  13. Federal Procurement Data System - FPDS API

    Data.gov (United States)

    General Services Administration — The Federal Procurement Data System (FPDS) Next Generation has been re-engineered as a real-time federal enterprise information system. Web services based on SOAP...

  14. First Identification of Nosema Ceranae (Microsporidia Infecting Apis Mellifera in Venezuela

    Directory of Open Access Journals (Sweden)

    Porrini Leonardo P.

    2017-06-01

    Full Text Available Nosema ceranae is a pathogen of Apis mellifera, which seems to have jumped from its original host Asiatic honey bee Apis ceranae. Nosemosis which affects the honey bee Apis mellifera is caused by two parasitic fungi described as etiologic agents of the disease. Nosema apis was the only microsporidian infection identified in A. mellifera until N. ceranae in Taiwan and Europe. Nosema spp. positive samples of adult worker bees from the Venezuelean state of Lara were determined through light microscopy of spores. Samples were then tested to determine Nosema species (N.apis/N.ceranae using previously reported PCR primers for the 16S rRNA gene. A multiplex PCR assay was used to differentiate both N. apis and N. ceranae species. Only N. ceranae was found in the analyzed samples and the percentage of infected foragers fluctuated between 18% and 60%.

  15. A Ruby API to query the Ensembl database for genomic features.

    Science.gov (United States)

    Strozzi, Francesco; Aerts, Jan

    2011-04-01

    The Ensembl database makes genomic features available via its Genome Browser. It is also possible to access the underlying data through a Perl API for advanced querying. We have developed a full-featured Ruby API to the Ensembl databases, providing the same functionality as the Perl interface with additional features. A single Ruby API is used to access different releases of the Ensembl databases and is also able to query multi-species databases. Most functionality of the API is provided using the ActiveRecord pattern. The library depends on introspection to make it release independent. The API is available through the Rubygem system and can be installed with the command gem install ruby-ensembl-api.

  16. Strategi Peningkatan Kualitas Pelayanan Jasa Transportasi Kereta Api (Studi Pada PT. Kereta Api Indonesia (Persero) Dearah Operasi VII Madiun)

    OpenAIRE

    Tri Juliyanto, Ilham

    2015-01-01

    : Quality Improvement Strategy Railway Transportation Services (Studi pada PT. Kereta Api Indonesia (Persero) Daerah Operasi VII Madiun). This research intended to discover the strategic which applied by PT. KAI DAOP VII Madiun for increasing the quality of service in train transportation, supporting factor and inhibiting factor strategic in increase of quality of service of PT. KAI DAOP VII Madiun. In this research, uses descriptive research with qualitative approach and use analysis method ...

  17. Pollination Effectiveness of Apis Cerana Fabricus and Apis Mellifera Linnaeus (Hymenoptera: Apidae) in Jatropha Curcas L. (Euphorbiaceae)

    OpenAIRE

    ATMOWIDI, TRI; RIYANTI, PUJI; SUTRISNA, ANDENG

    2008-01-01

    Pollinators are well known to provide key ecosystem. Animal pollinators are thought to contribute between 15 and 30% of global food production and bees are recognized to be the most important taxon. h e pollination eff ectiveness of two species of bees, Apis cerana and A. mellifera (Hymenoptera: Apidae) in Jatropha curcas (Euphorbiaceae) was studied. h ree cages, made of insect screen were set up. Each cage contains three individual plants. One colony of A. mellifera and A. cerana...

  18. Induction bending of API 5L X80 pipes; Curvamento a quente de tubos API 5L X80

    Energy Technology Data Exchange (ETDEWEB)

    Batista, Gilmar Z. [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil)]. E-mail: g.zacca@petrobras.com.br; Naschpitz, Leonardo [Primus Processamento de Tubos S.A. - PROTUBO, Campo Grande, RJ (Brazil)]. E-mail: naschpitz@protubo.com.br

    2005-07-01

    The present work is a part of an extensive program to make possible the application of API 5L X80 in pipeline construction in Brazil. At this stage, the effect of the induction bending process on the microstructure and mechanical properties of the pipe is presented. For this study an API 5L X80 pipe, made by the UOE process, is used. The pipe was manufactured from a plate produced by thermo-mechanically controlled rolling without accelerated cooling. The pipe bending was carried out applying a local induction heating following by water quenching. The bend section, outer and inner curvature regions, of the pipe bend were evaluated and compared with the original pipe. The longitudinal weld and transition zones were not evaluated at this stage. Dimensional analyses, microstructural evaluation, Charpy-V impact tests, and tensile tests were performed. A significant microstructural change was verified in the bend area. The yield strength of the pipe bend was found to be lower than original pipe and standard requirements. Other tensile properties and impact properties are compatible with API 5L X80 requirements. (author)

  19. Indiana Humanities Council Request for the Indianapolis Energy Conversion Inst. For Phase I of the Indianapolis Energy Conservation Res Initiative also called the smartDESKTOP Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Keller, John B.

    2007-12-06

    The smartDESKTOP Initiative at the Indiana Humanities Council received critical support in building and delivering a digital desktop for Indiana educators through the Department of Energy Grant DE-FG02-06ER64282. During the project period September 2006 through October of 2007, the number of Indiana educators with accounts on the smartDESKTOP more than tripled from under 2,000 to more than 7,000 accounts. An external review of the project conducted for the purposes of understanding the impact of the service in Indiana schools revealed that the majority of respondents felt that using the smartDESKTOP did reduce the time they spent managing paper. The same study revealed the challenges of implementing a digital desktop meant to help teachers leverage technology to improve their teaching and ultimately student learning. The most significant outcome of this project is that the Indiana Department of Education expressed interest in assuming responsibility for sustaining this project. The transition of the smartDESKTOP to the Indiana Department of Education was effective on November 1, 2007.

  20. The RNASeq-er API-a gateway to systematically updated analysis of public RNA-seq data.

    Science.gov (United States)

    Petryszak, Robert; Fonseca, Nuno A; Füllgrabe, Anja; Huerta, Laura; Keays, Maria; Tang, Y Amy; Brazma, Alvis

    2017-07-15

    The exponential growth of publicly available RNA-sequencing (RNA-Seq) data poses an increasing challenge to researchers wishing to discover, analyse and store such data, particularly those based in institutions with limited computational resources. EMBL-EBI is in an ideal position to address these challenges and to allow the scientific community easy access to not just raw, but also processed RNA-Seq data. We present a Web service to access the results of a systematically and continually updated standardized alignment as well as gene and exon expression quantification of all public bulk (and in the near future also single-cell) RNA-Seq runs in 264 species in European Nucleotide Archive, using Representational State Transfer. The RNASeq-er API (Application Programming Interface) enables ontology-powered search for and retrieval of CRAM, bigwig and bedGraph files, gene and exon expression quantification matrices (Fragments Per Kilobase Of Exon Per Million Fragments Mapped, Transcripts Per Million, raw counts) as well as sample attributes annotated with ontology terms. To date over 270 00 RNA-Seq runs in nearly 10 000 studies (1PB of raw FASTQ data) in 264 species in ENA have been processed and made available via the API. The RNASeq-er API can be accessed at http://www.ebi.ac.uk/fg/rnaseq/api . The commands used to analyse the data are available in supplementary materials and at https://github.com/nunofonseca/irap/wiki/iRAP-single-library . rnaseq@ebi.ac.uk ; rpetry@ebi.ac.uk. Supplementary data are available at Bioinformatics online. © The Author(s) 2017. Published by Oxford University Press.