WorldWideScience

Sample records for api based desktop

  1. APIs

    CERN Document Server

    Jacobson, Daniel; Woods, Dan

    2011-01-01

    Programmers used to be the only people excited about APIs, but now a growing number of companies see them as a hot new product channel. This concise guide describes the tremendous business potential of APIs, and demonstrates how you can use them to provide valuable services to clients, partners, or the public via the Internet. You'll learn all the steps necessary for building a cohesive API business strategy from experts in the trenches. Facebook and Twitter APIs continue to be extremely successful, and many other companies find that API demand greatly exceeds website traffic. This book offe

  2. Efficient Sustainable Operation Mechanism of Distributed Desktop Integration Storage Based on Virtualization with Ubiquitous Computing

    Directory of Open Access Journals (Sweden)

    Hyun-Woo Kim

    2015-06-01

    Full Text Available Following the rapid growth of ubiquitous computing, many jobs that were previously manual have now been automated. This automation has increased the amount of time available for leisure; diverse services are now being developed for this leisure time. In addition, the development of small and portable devices like smartphones, diverse Internet services can be used regardless of time and place. Studies regarding diverse virtualization are currently in progress. These studies aim to determine ways to efficiently store and process the big data generated by the multitude of devices and services in use. One topic of such studies is desktop storage virtualization, which integrates distributed desktop resources and provides these resources to users to integrate into distributed legacy desktops via virtualization. In the case of desktop storage virtualization, high availability of virtualization is necessary and important for providing reliability to users. Studies regarding hierarchical structures and resource integration are currently in progress. These studies aim to create efficient data distribution and storage for distributed desktops based on resource integration environments. However, studies regarding efficient responses to server faults occurring in desktop-based resource integration environments have been insufficient. This paper proposes a mechanism for the sustainable operation of desktop storage (SODS for high operational availability. It allows for the easy addition and removal of desktops in desktop-based integration environments. It also activates alternative servers when a fault occurs within a system.

  3. An Implementation Model of Parlay MMCCS API Based on SIP

    Institute of Scientific and Technical Information of China (English)

    GUAN You-qing; SHEN Su-bin

    2006-01-01

    Parlay Multi Media Call Control Services(MMCCS) Application Programming Interfaces (API) based on Session Initiation Protocol (SIP) is essential for the implementation of Parlay Call Control (CC) API. This paper first proposes an implementation model of Parlay MMCCS API based on SIP, then presents a mapping between SIP and MMCCS API as far as methods and parameters are concerned, illustrates corresponding relationships between different components of SIP and MMCCS API by means of an application collaboration diagram, and finally presents an application using Java codes as well as some SIP messages. The application shows that a majority of MMCCS API based on SIP can be implemented and therefore verifies our mapping between MMCCS API and SIP.

  4. A desktop extreme ultraviolet microscope based on a compact laser-plasma light source

    Science.gov (United States)

    Wachulak, P. W.; Torrisi, A.; Bartnik, A.; Węgrzyński, Ł.; Fok, T.; Fiedorowicz, H.

    2017-01-01

    A compact, desktop size microscope, based on laser-plasma source and equipped with reflective condenser and diffractive Fresnel zone plate objective, operating in the extreme ultraviolet (EUV) region at the wavelength of 13.8 nm, was developed. The microscope is capable of capturing magnified images of objects with 95-nm full-pitch spatial resolution (48 nm 25-75% KE) and exposure time as low as a few seconds, combining reasonable acquisition conditions with stand-alone desktop footprint. Such EUV microscope can be regarded as a complementary imaging tool to already existing, well-established ones. Details about the microscope, characterization, resolution estimation and real sample images are presented and discussed.

  5. An Android-based Remote Desktop for IOS Platforms

    Directory of Open Access Journals (Sweden)

    Siew-Chin Chong

    2013-09-01

    Full Text Available Thanks to globalization, mobile devices have become an inseparable entity of our daily life. We often expect our smart devices (mobile phone, tablet, portable media player to possess the functionalities of a personal computer. As the technology is getting cheaper, owning multiple mobile devices, each for a specific purpose, is becoming the current trend. For instance, an Android smartphone to fulfill a user’s communication needs on-the-go, an iPad could serve the user’s reading hobby, and lastly, a laptop for productivity activities. As such, to switch among different devices could be the emerging problem of the current generation. With our proposed Android based remote control app, a user does not only able to control his Windows based office laptop, but he could access to his IOS based devices too. Besides click event and text input, this application also supports panning and zooming gesture inputs.

  6. Agent-based modeling and simulation Part 3 : desktop ABMS.

    Energy Technology Data Exchange (ETDEWEB)

    Macal, C. M.; North, M. J.; Decision and Information Sciences

    2007-01-01

    Agent-based modeling and simulation (ABMS) is a new approach to modeling systems comprised of autonomous, interacting agents. ABMS promises to have far-reaching effects on the way that businesses use computers to support decision-making and researchers use electronic laboratories to support their research. Some have gone so far as to contend that ABMS 'is a third way of doing science,' in addition to traditional deductive and inductive reasoning (Axelrod 1997b). Computational advances have made possible a growing number of agent-based models across a variety of application domains. Applications range from modeling agent behavior in the stock market, supply chains, and consumer markets, to predicting the spread of epidemics, the threat of bio-warfare, and the factors responsible for the fall of ancient civilizations. This tutorial describes the theoretical and practical foundations of ABMS, identifies toolkits and methods for developing agent models, and illustrates the development of a simple agent-based model of shopper behavior using spreadsheets.

  7. A Desk-top tutorial Demonstration of Model-based Fault Detection and Diagnosis

    OpenAIRE

    Shi, John Z.; Elshanti, Ali; Gu, Fengshou; Ball, Andrew

    2007-01-01

    In this paper, a demonstration on the model-based approach for fault detection has been presented. The aim of this demo is to provide students a desk-top tool to start learning model-based approach. The demo works on a traditional three-tank system. After a short review of the model-based approach, this paper emphasizes on two difficulties often asked by students when they start learning model-based approach: how to develop a system model and how to generate residual for fault detection. The ...

  8. Semantic Desktop

    Science.gov (United States)

    Sauermann, Leo; Kiesel, Malte; Schumacher, Kinga; Bernardi, Ansgar

    In diesem Beitrag wird gezeigt, wie der Arbeitsplatz der Zukunft aussehen könnte und wo das Semantic Web neue Möglichkeiten eröffnet. Dazu werden Ansätze aus dem Bereich Semantic Web, Knowledge Representation, Desktop-Anwendungen und Visualisierung vorgestellt, die es uns ermöglichen, die bestehenden Daten eines Benutzers neu zu interpretieren und zu verwenden. Dabei bringt die Kombination von Semantic Web und Desktop Computern besondere Vorteile - ein Paradigma, das unter dem Titel Semantic Desktop bekannt ist. Die beschriebenen Möglichkeiten der Applikationsintegration sind aber nicht auf den Desktop beschränkt, sondern können genauso in Web-Anwendungen Verwendung finden.

  9. FEASIBILITY OF DESKTOP VIRTUALIZATION PER SOFTWARE SERVICES AND LOCAL HARDWARE BASED ON THE NETWORK THROUGHPUT

    Directory of Open Access Journals (Sweden)

    Vitor Chaves De Oliveira

    2013-01-01

    Full Text Available In recent years, virtualization computing has become a worldwide reality present in datacenters servers of most organizations. The motivations for the use of this solution are focused primarily on cost reduction and increases in availability, integrity and security of data. Based on these benefits, recently it was started the use of this technology for personal computers as well. That is, for desktops, giving birth to the so-called desktop virtualization. Given the technical advantages of the approach, its growth has been so significant that, before 2014, it is expected to be present in over 90% of organizations. However, this new method is completely based on a physical client-server architecture, which increases the importance of the communication network that makes this technique possible. Therefore, analyzing the network in order to investigate the effects according to the environment implemented becomes crucial. In this study it’s varied the local’s client hardware and the application, i.e., the service used. The purpose was to detail their effects on computer networks in a Quality of Service (QoS parameter, throughput. Secondarily are outlined perceptions regarding the Quality of Experience (QoE? This culminated in an assessment that traces the feasibility for applying this technology.

  10. CLOUD-BASED VS DESKTOP-BASED PROPERTY MANAGEMENT SYSTEMS IN HOTEL

    Directory of Open Access Journals (Sweden)

    Mustafa\tGULMEZ

    2015-06-01

    Full Text Available Even though keeping up with the modern developments in IT sector is crucial for the success and competitiveness of a hotel, it is usually very hard for new technologies to be accepted and implemented. This is the case with the cloud technology for which the opinions between hoteliers are divided on those who think that it is just another fashion trend, unnecessary to be taken into consideration and those that believe that it helps in performing daily operations more easily, leaving space for more interaction with guests both in virtual and real world. Usage of cloud technology in hotels is still in its beginning phase and hoteliers still have to learn more about its advantages and adequate usage for the benefit of overall hotel operating. On the example of hotel property management system (PMS and comparison between features of its older desktop-version and new web-based programs, this research aims at finding out at which stage and how effective is usage of cloud technology in hotels. For this, qualitative research with semi-structured interviews with hotel mangers that use one of these programs was conducted. Reasons for usage and advantages of each version are discussed.

  11. Metadata and API Based Environment Aware Content Delivery Architecture

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    One of the limitations of current content delivery networks is lack of support for environment aware content delivery. This paper first discusses the requirements of such support, and proposes a new metadata gateway based environment aware content delivery architecture. The paper discusses in some details key functions and technologies of environment aware content delivery architecture, including its APIs and control policies. Finally the paper presents an application to illustrate advantages of environment aware content delivery architecture in the context of next generation network.

  12. Economic analysis of cloud-based desktop virtualization implementation at a hospital

    Directory of Open Access Journals (Sweden)

    Yoo Sooyoung

    2012-10-01

    Full Text Available Abstract Background Cloud-based desktop virtualization infrastructure (VDI is known as providing simplified management of application and desktop, efficient management of physical resources, and rapid service deployment, as well as connection to the computer environment at anytime, anywhere with anydevice. However, the economic validity of investing in the adoption of the system at a hospital has not been established. Methods This study computed the actual investment cost of the hospital-wide VDI implementation at the 910-bed Seoul National University Bundang Hospital in Korea and the resulting effects (i.e., reductions in PC errors and difficulties, application and operating system update time, and account management time. Return on investment (ROI, net present value (NPV, and internal rate of return (IRR indexes used for corporate investment decision-making were used for the economic analysis of VDI implementation. Results The results of five-year cost-benefit analysis given for 400 Virtual Machines (VMs; i.e., 1,100 users in the case of SNUBH showed that the break-even point was reached in the fourth year of the investment. At that point, the ROI was 122.6%, the NPV was approximately US$192,000, and the IRR showed an investment validity of 10.8%. From our sensitivity analysis to changing the number of VMs (in terms of number of users, the greater the number of adopted VMs was the more investable the system was. Conclusions This study confirms that the emerging VDI can have an economic impact on hospital information system (HIS operation and utilization in a tertiary hospital setting.

  13. Efficiency Sustainability Resource Visual Simulator for Clustered Desktop Virtualization Based on Cloud Infrastructure

    Directory of Open Access Journals (Sweden)

    Jong Hyuk Park

    2014-11-01

    Full Text Available Following IT innovations, manual operations have been automated, improving the overall quality of life. This has been possible because an organic topology has been formed among many diverse smart devices grafted onto real life. To provide services to these smart devices, enterprises or users use the cloud. Cloud services are divided into infrastructure as a service (IaaS, platform as a service (PaaS and software as a service (SaaS. SaaS is operated on PaaS, and PaaS is operated on IaaS. Since IaaS is the foundation of all services, algorithms for the efficient operation of virtualized resources are required. Among these algorithms, desktop resource virtualization is used for high resource availability when existing desktop PCs are unavailable. For this high resource availability, clustering for hierarchical structures is important. In addition, since many clustering algorithms show different percentages of the main resources depending on the desktop PC distribution rates and environments, selecting appropriate algorithms is very important. If diverse attempts are made to find algorithms suitable for the operating environments’ desktop resource virtualization, huge costs are incurred for the related power, time and labor. Therefore, in the present paper, a desktop resource virtualization clustering simulator (DRV-CS, a clustering simulator for selecting clusters of desktop virtualization clusters to be maintained sustainably, is proposed. The DRV-CS provides simulations, so that clustering algorithms can be selected and elements can be properly applied in different desktop PC environments through the DRV-CS.

  14. A SNP based high-density linkage map of Apis cerana reveals a high recombination rate similar to Apis mellifera.

    Directory of Open Access Journals (Sweden)

    Yuan Yuan Shi

    Full Text Available BACKGROUND: The Eastern honey bee, Apis cerana Fabricius, is distributed in southern and eastern Asia, from India and China to Korea and Japan and southeast to the Moluccas. This species is also widely kept for honey production besides Apis mellifera. Apis cerana is also a model organism for studying social behavior, caste determination, mating biology, sexual selection, and host-parasite interactions. Few resources are available for molecular research in this species, and a linkage map was never constructed. A linkage map is a prerequisite for quantitative trait loci mapping and for analyzing genome structure. We used the Chinese honey bee, Apis cerana cerana to construct the first linkage map in the Eastern honey bee. RESULTS: F2 workers (N = 103 were genotyped for 126,990 single nucleotide polymorphisms (SNPs. After filtering low quality and those not passing the Mendel test, we obtained 3,000 SNPs, 1,535 of these were informative and used to construct a linkage map. The preliminary map contains 19 linkage groups, we then mapped the 19 linkage groups to 16 chromosomes by comparing the markers to the genome of A. mellfiera. The final map contains 16 linkage groups with a total of 1,535 markers. The total genetic distance is 3,942.7 centimorgans (cM with the largest linkage group (180 loci measuring 574.5 cM. Average marker interval for all markers across the 16 linkage groups is 2.6 cM. CONCLUSION: We constructed a high density linkage map for A. c. cerana with 1,535 markers. Because the map is based on SNP markers, it will enable easier and faster genotyping assays than randomly amplified polymorphic DNA or microsatellite based maps used in A. mellifera.

  15. Towards Standardized Patient Data Exchange: Integrating a FHIR Based API for the Open Medical Record System.

    Science.gov (United States)

    Kasthurirathne, Suranga N; Mamlin, Burke; Grieve, Grahame; Biondich, Paul

    2015-01-01

    Interoperability is essential to address limitations caused by the ad hoc implementation of clinical information systems and the distributed nature of modern medical care. The HL7 V2 and V3 standards have played a significant role in ensuring interoperability for healthcare. FHIR is a next generation standard created to address fundamental limitations in HL7 V2 and V3. FHIR is particularly relevant to OpenMRS, an Open Source Medical Record System widely used across emerging economies. FHIR has the potential to allow OpenMRS to move away from a bespoke, application specific API to a standards based API. We describe efforts to design and implement a FHIR based API for the OpenMRS platform. Lessons learned from this effort were used to define long term plans to transition from the legacy OpenMRS API to a FHIR based API that greatly reduces the learning curve for developers and helps enhance adhernce to standards.

  16. 基于GIS的桌面应急演练系统%GIS-BASED DESKTOP EMERGENCY DRILLING SYSTEM

    Institute of Scientific and Technical Information of China (English)

    陈诚; 张敬谊; 童庆; 吴东保

    2013-01-01

    为了减少化学气体泄漏事故的伤害和损失,研究开发一个基于GIS的桌面应急演练系统.该系统采用基于高斯烟团模型的新模型和新数值化仿真运算算法模拟气体扩散,并采用一种车辆紧急调度模型和启发式求解算法进行人员调度疏散演练.最后,该系统在Flex架构下实现了前端交互式界面.桌面应急演练系统的研究有助于应急管理的信息化和智能化.%In order to reduce the injuries and losses in chemical gas leakage accidents, in this paper we develop a GIS-based desktop emergency drilling system. The system simulates the gas diffusion using a Gaussian Puff Model-based new model and a new numerical simulation operation algorithm, and adopts an emergent vehicle dispatching model and a heuristic algorithm to practise the personnel scheduling and evacuation drill. At last, the system realises the front-end interactive interface in Adobe Flex architecture. The study on desktop emergency drilling system helps the intelligence and informatisation of the emergency management.

  17. Desktop Virtualization: Applications and Considerations

    Science.gov (United States)

    Hodgman, Matthew R.

    2013-01-01

    As educational technology continues to rapidly become a vital part of a school district's infrastructure, desktop virtualization promises to provide cost-effective and education-enhancing solutions to school-based computer technology problems in school systems locally and abroad. This article outlines the history of and basic concepts behind…

  18. 基于桌面虚拟化技术的新型IT办公环境%New Style IT Workplace Based on Desktop Virtualization

    Institute of Scientific and Technical Information of China (English)

    尹勤

    2012-01-01

    基于桌面虚拟化技术在企业内部IT桌面工作环境应用的研究,从虚拟化技术的发展、分类和特点出发,分析了硬件虚拟化、桌面虚拟化和应用虚拟化等技术的优缺点.还分析了目前企业内部桌面系统管理和维护所存在的问题及挑战、桌面虚拟化技术对于传统企业IT桌面应用系统的改进以及企业内部IT管理和成本控制等方面带来的优势.%This paper is based on the research of solution to IT desktop applications in a company. It begins with the history and development of virtualization, and then analyzes advantage and disadvantage of hardware virtualization, desktop virtualization and application visualization. At the end it analyzes the challenges of traditional desktop system in the company and benefits of implementing desktop virtualization.

  19. Linux Desktop Pocket Guide

    CERN Document Server

    Brickner, David

    2005-01-01

    While Mac OS X garners all the praise from pundits, and Windows XP attracts all the viruses, Linux is quietly being installed on millions of desktops every year. For programmers and system administrators, business users, and educators, desktop Linux is a breath of fresh air and a needed alternative to other operating systems. The Linux Desktop Pocket Guide is your introduction to using Linux on five of the most popular distributions: Fedora, Gentoo, Mandriva, SUSE, and Ubuntu. Despite what you may have heard, using Linux is not all that hard. Firefox and Konqueror can handle all your web bro

  20. Desktop grid computing

    CERN Document Server

    Cerin, Christophe

    2012-01-01

    Desktop Grid Computing presents common techniques used in numerous models, algorithms, and tools developed during the last decade to implement desktop grid computing. These techniques enable the solution of many important sub-problems for middleware design, including scheduling, data management, security, load balancing, result certification, and fault tolerance. The book's first part covers the initial ideas and basic concepts of desktop grid computing. The second part explores challenging current and future problems. Each chapter presents the sub-problems, discusses theoretical and practical

  1. Desktop Manufacturing Technologies.

    Science.gov (United States)

    Snyder, Mark

    1991-01-01

    Desktop manufacturing is the use of data from a computer-assisted design system to construct actual models of an object. Emerging processes are stereolithography, laser sintering, ballistic particle manufacturing, laminated object manufacturing, and photochemical machining. (SK)

  2. VMware Horizon 6 desktop virtualization solutions

    CERN Document Server

    Cartwright, Ryan; Langone, Jason; Leibovici, Andre

    2014-01-01

    If you are a desktop architect, solution provider, end-user consultant, virtualization engineer, or anyone who wants to learn how to plan and design the implementation of a virtual desktop solution based on Horizon 6, then this book is for you. An understanding of VMware vSphere fundamentals coupled with experience in the installation or administration of a VMware environment would be a plus during reading.

  3. 一种基于新型图模型的 API 推荐系统%APISynth:A New Graph-Based API Recommender System

    Institute of Scientific and Technical Information of China (English)

    吕晨; 姜伟; 虎嵩林

    2015-01-01

    对象实例化是软件工程类库复用中一个常见、复杂的问题.即根据已知源类型的对象,用户需要编写代码对目标类型进行实例化.研究人员提出了若干种 API 自动推荐系统辅助用户解决上述问题.然而这些系统不能同时兼顾准确率和查全率,因此在一定程度上影响了系统的实用性.该文提出了一种兼顾准确率和查全率,基于新型图模型的 API 推荐系统———APISynth.在查全率方面,APISynth 使用一个新颖的全局图模型来表达类库中所有的API 依赖关系和 API 历史使用信息.利用新的全局图模型具有的特殊 Tag 元素和可达性质以避免错误的 API 调用.在准确率方面,APISynth 首先将对象实例化问题建模为 Top-K 子图查询问题,然后设计一种新的支持 DAG 形式解的图搜索算法,避免了传统的最短路径图搜索算法导致的查不准问题.实验结果表明,与现有多种方法相比, APISynth 在准确率和查全率两方面均获得了较大提升.%How to perform object instantiation is a common and complex problem in reusing an existing library.In this problem,given the object of source type,users need to write code to instantiate the destination type.Recently,researchers have proposed a variety of related API automatic recommender systems to fulfill this problem.These systems can assist users to solve the above issue in some degree.However,it is very difficult for such systems to achieve both good recall and precision,which affects the usability.This paper presents APISynth,a new graph-based API recommender system.In order to improve the recall,APISynth utilizes a new global graph model to give a better representation for the API dependencies in the relevant class library,and to include API historical usage information in.A special tag element is added to the new graph together with a new reach ability property to avoid false invocation of APIs

  4. Desktop Computing Integration Project

    Science.gov (United States)

    Tureman, Robert L., Jr.

    1992-01-01

    The Desktop Computing Integration Project for the Human Resources Management Division (HRMD) of LaRC was designed to help division personnel use personal computing resources to perform job tasks. The three goals of the project were to involve HRMD personnel in desktop computing, link mainframe data to desktop capabilities, and to estimate training needs for the division. The project resulted in increased usage of personal computers by Awards specialists, an increased awareness of LaRC resources to help perform tasks, and personal computer output that was used in presentation of information to center personnel. In addition, the necessary skills for HRMD personal computer users were identified. The Awards Office was chosen for the project because of the consistency of their data requests and the desire of employees in that area to use the personal computer.

  5. HTTP-based Search and Ordering Using ECHO's REST-based and OpenSearch APIs

    Science.gov (United States)

    Baynes, K.; Newman, D. J.; Pilone, D.

    2012-12-01

    Metadata is an important entity in the process of cataloging, discovering, and describing Earth science data. NASA's Earth Observing System (EOS) ClearingHOuse (ECHO) acts as the core metadata repository for EOSDIS data centers, providing a centralized mechanism for metadata and data discovery and retrieval. By supporting both the ESIP's Federated Search API and its own search and ordering interfaces, ECHO provides multiple capabilities that facilitate ease of discovery and access to its ever-increasing holdings. Users are able to search and export metadata in a variety of formats including ISO 19115, json, and ECHO10. This presentation aims to inform technically savvy clients interested in automating search and ordering of ECHO's metadata catalog. The audience will be introduced to practical and applicable examples of end-to-end workflows that demonstrate finding, sub-setting and ordering data that is bound by keyword, temporal and spatial constraints. Interaction with the ESIP OpenSearch Interface will be highlighted, as will ECHO's own REST-based API.

  6. 桌面式眼动跟踪系统研究%Eye Tracking Technology Research Based on Desktop

    Institute of Scientific and Technical Information of China (English)

    董大洼; 董兰芳; 余家奎; 王建富

    2014-01-01

    Human-Computer Interaction (HCI) has witnessed a tremendous growth in the past decade, as a new means of HCI, eye tracking technology has been more and more popular, some company have already released eye tracking system, but most of them are expensive, invasive and not user-friendly. This paper implements a simple eye tracking system based on the desktop, its hardware structure is simple, and no direct contact with people, uses the iris center coordinates to estimate the user's gaze. The experiments show that when the distance error is less than 40 pixels, the method used to calculate the human eye gaze has an accuracy of more than 80%.%眼动跟踪技术作为一种新的人机交互方式,已受到越来越多人的关注,现有的眼动跟踪系统大都是头戴式的,它的硬件设备复杂,对人干扰较大,而且价格昂贵。文章实现了一个简单的基于桌面的眼动跟踪系统,本系统硬件构成简单,而且不与人直接接触,使用虹膜中心坐标来估计用户的注视点。实验表明,当误差距离不超过40个像素时,系统估计的人眼注视点准确率超过80%。

  7. [Teaching Desktop] Video Conferencing in a Collaborative and Problem Based Setting

    DEFF Research Database (Denmark)

    Ørngreen, Rikke; Mouritzen, Per

    2013-01-01

    of delay and sound problems, where different embodiment and space‐design influence the learning process. However, we also find that the PBL‐setup inspires the students to apply theory into practice and to reflect on their own practice, furthermore the collaborative approach support the feeling of trust......This paper presents experiences from teaching video conferencing for learning and collaboration, and discusses the challenges and potentials of applying a collaborative and problem‐based learning (PBL) pedagogy. The research is an action research study, and we as researchers, educational planners...... conferences. We studied 3 subsequent years of a master program module on video conferencing, and the changes it has undergone. The participants work in groups and each group has the task of designing a short one hour (45min) educational design of their own choice. The students have to try out and evaluate...

  8. Lung segmentation refinement based on optimal surface finding utilizing a hybrid desktop/virtual reality user interface.

    Science.gov (United States)

    Sun, Shanhui; Sonka, Milan; Beichel, Reinhard R

    2013-01-01

    Recently, the optimal surface finding (OSF) and layered optimal graph image segmentation of multiple objects and surfaces (LOGISMOS) approaches have been reported with applications to medical image segmentation tasks. While providing high levels of performance, these approaches may locally fail in the presence of pathology or other local challenges. Due to the image data variability, finding a suitable cost function that would be applicable to all image locations may not be feasible. This paper presents a new interactive refinement approach for correcting local segmentation errors in the automated OSF-based segmentation. A hybrid desktop/virtual reality user interface was developed for efficient interaction with the segmentations utilizing state-of-the-art stereoscopic visualization technology and advanced interaction techniques. The user interface allows a natural and interactive manipulation of 3-D surfaces. The approach was evaluated on 30 test cases from 18 CT lung datasets, which showed local segmentation errors after employing an automated OSF-based lung segmentation. The performed experiments exhibited significant increase in performance in terms of mean absolute surface distance errors (2.54±0.75 mm prior to refinement vs. 1.11±0.43 mm post-refinement, p≪0.001). Speed of the interactions is one of the most important aspects leading to the acceptance or rejection of the approach by users expecting real-time interaction experience. The average algorithm computing time per refinement iteration was 150 ms, and the average total user interaction time required for reaching complete operator satisfaction was about 2 min per case. This time was mostly spent on human-controlled manipulation of the object to identify whether additional refinement was necessary and to approve the final segmentation result. The reported principle is generally applicable to segmentation problems beyond lung segmentation in CT scans as long as the underlying segmentation utilizes the

  9. Speed Improvement of Desktop 3D Printer Based on FDM%基于FDM的桌面型3D打印机速度提升技术

    Institute of Scientific and Technical Information of China (English)

    伍倪燕; 傅贵兴; 廖璘志

    2016-01-01

    由于桌面型3D打印机是一种以数字模型文件为基础的累积制造技术,容易受到打印速度的影响降低打印机工作效率,传统的桌面型3D打印机采用单路固定数据传输和逐层打印的方式,增加了打印时间,导致打印速度慢的问题。提出基于频分多路复用(FDM)的桌面型3D打印机速度提升算法。分析了桌面型3D打印机的工作原理,设计桌面型3D打印机的喷墨控制模型,采用打印效率和打印速度对偶分析方法,融入频分多路复用(FDM)方法实现桌面型3D打印机的多目标集优化控制,并对速度量化指标进行评估,根据不同频率传送各路打印请求消息,实现打印速度提升。仿真实验表明,该技术能有效降低各路打印输入信号的干扰频谱,实现3D打印机的喷墨准确控制,大幅降低打印时间和内存开销,提高打印速度。%Desktop 3 d printer is a kind of based on the digital model file, the accumulation of manufacturing technology of 3 d printers print speed is one of the important parameters reflect the printer work efficiency, the traditional desktop 3 d printer using single-channel fixed data transmission, affect the printing speed. Based on frequency division multiplexing (FDM) desktop 3 d printer faster algorithm. Desktop 3 d printer is analyzed the working principle of the design of a desktop 3 d printer ink jet control model, the printing and printing speed dual efficiency analysis method, integrated into the frequency division multiplexing (FDM) method implementation desktop 3 d printer set of multi-objective optimal control, and to evaluate speed quantitative indicators, according to the different frequency transfer print request message of all stripes, printing speed. Simulation experiments show that the technology can effectively reduce various print spectrum of input signal, realizes the 3 d printer inkjet accurate control, greatly reduce printing time and

  10. Desk Congest Desktop Congesting Software for Desktop Clutter Congestion

    Directory of Open Access Journals (Sweden)

    Solomon A. Adepoju

    2015-06-01

    Full Text Available Abstract The computer desktop environment is a working environment which can be likened unto a users desk in homes and offices. Often times the computer desktop get cluttered with files either as shortcuts used for quick links files stored temporarily to be accessed later or just being dumped there for no vivid reasons. However previous researches have shown that cluttered desktop affects users productivity and getting these files organized is a laborious task for most users. To be able to conveniently alleviate the effect clutters have on users performances and productivity there is need for third party software that will help get the desktop environment organized in a logical and efficient manner. It is to this end that desktop decongesting software is being designed and implemented to help curb clutter problems which existing tools have only partially addressed. The system is designed using Visual Basic .Net and it proves to be effective in tackling desktop congestion problem.

  11. Corporate Consumer Contact API

    Data.gov (United States)

    General Services Administration — The data in the Corporate Consumer Contact API is based on the content you can find in the Corporate Consumer Contact listing in the Consumer Action Handbook (PDF)....

  12. Risk analysis of heat recovery steam generator with semi quantitative risk based inspection API 581

    Science.gov (United States)

    Prayogo, Galang Sandy; Haryadi, Gunawan Dwi; Ismail, Rifky; Kim, Seon Jin

    2016-04-01

    Corrosion is a major problem that most often occurs in the power plant. Heat recovery steam generator (HRSG) is an equipment that has a high risk to the power plant. The impact of corrosion damage causing HRSG power plant stops operating. Furthermore, it could be threaten the safety of employees. The Risk Based Inspection (RBI) guidelines by the American Petroleum Institute (API) 58 has been used to risk analysis in the HRSG 1. By using this methodology, the risk that caused by unexpected failure as a function of the probability and consequence of failure can be estimated. This paper presented a case study relating to the risk analysis in the HRSG, starting with a summary of the basic principles and procedures of risk assessment and applying corrosion RBI for process industries. The risk level of each HRSG equipment were analyzed: HP superheater has a medium high risk (4C), HP evaporator has a medium-high risk (4C), and the HP economizer has a medium risk (3C). The results of the risk assessment using semi-quantitative method of standard API 581 based on the existing equipment at medium risk. In the fact, there is no critical problem in the equipment components. Damage mechanisms were prominent throughout the equipment is thinning mechanism. The evaluation of the risk approach was done with the aim of reducing risk by optimizing the risk assessment activities.

  13. Streamlining Metadata Ingest and Discovery Using ECHO's REST-based API

    Science.gov (United States)

    Ericson, R.; Baynes, K.; Pilone, D.

    2012-12-01

    Enabling user access to Earth science data is a primary goal of NASA's Earth Observing System Data and Information Systems (EOSDIS) programs. NASA's Earth Observing System ClearingHOuse (ECHO) acts as the core metadata repository for EOSDIS's data centers, providing a centralized mechanism for metadata and data discovery and retrieval. ECHO has recently made strides to restructure its API; allowing data partners to streamline and synchronize their metadata ingest using RESTful web services. ECHO's legacy ingest process involves data uploads via FTP with asynchronous result reporting. Data centers provide single xml files or compressed data (zip) files that are unpacked, indexed and stored in ECHO data tables for future search and retrieval. Any problems related to metadata validation and ingest are reported after batch processing of discrete jobs have been completed. With ECHO's new REST-based web services, data providers will receive immediate feedback about the status of their ingested data and can ensure that their data exports are successful as soon as the data is posted to our repository. This presentation will introduce ECHO's potential new and existing data partners to the process of implementing data ingest via its RESTful web services API, providing real-world examples of end-to-end metadata management. Examples of ECHO's support of multi-format metadata ingest using both ECHO10 and ISO 19115 metadata formats will be showcased. This presentation will also pay special attention to tuning a provider's metadata, making it more easily searched and accessed via ECHO's various interfaces.

  14. A web-based remote radiation treatment planning system using the remote desktop function of a computer operating system: a preliminary report.

    Science.gov (United States)

    Suzuki, Keishiro; Hirasawa, Yukinori; Yaegashi, Yuji; Miyamoto, Hideki; Shirato, Hiroki

    2009-01-01

    We developed a web-based, remote radiation treatment planning system which allowed staff at an affiliated hospital to obtain support from a fully staffed central institution. Network security was based on a firewall and a virtual private network (VPN). Client computers were installed at a cancer centre, at a university hospital and at a staff home. We remotely operated the treatment planning computer using the Remote Desktop function built in to the Windows operating system. Except for the initial setup of the VPN router, no special knowledge was needed to operate the remote radiation treatment planning system. There was a time lag that seemed to depend on the volume of data traffic on the Internet, but it did not affect smooth operation. The initial cost and running cost of the system were reasonable.

  15. A Web-Based Interactive Mapping System of State Wide School Performance: Integrating Google Maps API Technology into Educational Achievement Data

    Science.gov (United States)

    Wang, Kening; Mulvenon, Sean W.; Stegman, Charles; Anderson, Travis

    2008-01-01

    Google Maps API (Application Programming Interface), released in late June 2005 by Google, is an amazing technology that allows users to embed Google Maps in their own Web pages with JavaScript. Google Maps API has accelerated the development of new Google Maps based applications. This article reports a Web-based interactive mapping system…

  16. Cloud Desktop Construction Based on Hyper-V Technology%基于Hyper-V技术的云桌面构建

    Institute of Scientific and Technical Information of China (English)

    卞昌军

    2016-01-01

    This paper,based on the analysis of the current situation and problems in the development of laboratory in vocational colle-ges,proposes a method using Hyper-V technology to virtualize server clusters,and constructs laboratory cloud desktop,which is realized in the laboratory by using the method above.%在分析现有高职院校实验室的发展现状与存在问题的基础上,给出一种利用Hyper-V技术对服务器群集进行虚拟化,从而构建实验室云桌面的方法,并已经在实验室中进行详细部署实现。

  17. Helioviewer API

    Data.gov (United States)

    National Aeronautics and Space Administration — The Helioviewer Project maintains a set of Public APIs with the goal of improving access to solar and heliospheric datasets to scientists, educators, developers,...

  18. Recalls API

    Data.gov (United States)

    General Services Administration — This Recalls API allows you to tap into a list of (1) drug and food safety recalls from the Food and Drug Administration, Food Safety and Inspection Service, and...

  19. Jobs API

    Data.gov (United States)

    General Services Administration — This Jobs API returns job openings across the federal government and includes all current openings posted on USAJobs.gov that are open to the public and located in...

  20. Design and Implement AN Interoperable Internet of Things Application Based on AN Extended Ogc Sensorthings Api Standard

    Science.gov (United States)

    Huang, C. Y.; Wu, C. H.

    2016-06-01

    The Internet of Things (IoT) is an infrastructure that interconnects uniquely-identifiable devices using the Internet. By interconnecting everyday appliances, various monitoring and physical mashup applications can be constructed to improve people's daily life. However, IoT devices created by different manufacturers follow different proprietary protocols and cannot communicate with each other. This heterogeneity issue causes different products to be locked in multiple closed ecosystems that we call IoT silos. In order to address this issue, a common industrial solution is the hub approach, which implements connectors to communicate with IoT devices following different protocols. However, with the growing number of proprietary protocols proposed by device manufacturers, IoT hubs need to support and maintain a lot of customized connectors. Hence, we believe the ultimate solution to address the heterogeneity issue is to follow open and interoperable standard. Among the existing IoT standards, the Open Geospatial Consortium (OGC) SensorThings API standard supports comprehensive conceptual model and query functionalities. The first version of SensorThings API mainly focuses on connecting to IoT devices and sharing sensor observations online, which is the sensing capability. Besides the sensing capability, IoT devices could also be controlled via the Internet, which is the tasking capability. While the tasking capability was not included in the first version of the SensorThings API standard, this research aims on defining the tasking capability profile and integrates with the SensorThings API standard, which we call the extended-SensorThings API in this paper. In general, this research proposes a lightweight JSON-based web service description, the "Tasking Capability Description", allowing device owners and manufacturers to describe different IoT device protocols. Through the extended- SensorThings API, users and applications can follow a coherent protocol to control Io

  1. API testing program - calibration of microprocessor based flowmeters for integrated metering systems

    Energy Technology Data Exchange (ETDEWEB)

    Elliot, Kenneth D. [Omni Flow Computers, Inc., Stafford, TX (United States)

    2005-07-01

    Microprocessor based flowmeter technologies for liquids, such as Coriolis mass meters, and Ultrasonic flowmeters hold great promise. These technologies offer many advantages, such as no rotating parts, self-diagnostic checks, which can help anticipate and warn of impending failures before they have a major impact on the measurement. These meters are substantially different though than other primary devices due to their heavy reliance on the accompanying secondary electronics. One method to prove that they are accurate would be proving the flowmeter, using a pipe prover or small volume prover (SVP), but these proving methods are designed to count 'real time' pulses from a turbine or PD meter between a known volume, they are not designed to count 'time delayed' 'manufactured pulses' from a microprocessor. There are limitations of the manufactured pulse train and it affects the ability of the flowmeter to be proved using current proving technology. The author of this paper, a chairman of an American Petroleum Institute working group, investigated how the 'microprocessor generated pulses' produced by these types of flowmeters, interacted with the existing measurement technologies in use today. Several microprocessor based flowmeter technologies have been tested, including; Ultrasonic, Coriolis, and Helical Turbine with pulse multiplying preamplifier. Wherever possible, flowmeters of various sizes, and from several vendors have been tested. A significant amount of data has been collected which sheds light into why these types of flowmeters are sometimes difficult to prove. This paper describes the API testing program, and the methodology behind it. It presents results and findings, and offers specific recommendations that may eventually be incorporated into API documents and/or standards in the future. (author)

  2. Correlation Between Microstructures and Tensile Properties of Strain-Based API X60 Pipeline Steels

    Science.gov (United States)

    Sung, Hyo Kyung; Lee, Dong Ho; Lee, Sunghak; Kim, Hyoung Seop; Ro, Yunjo; Lee, Chang Sun; Hwang, Byoungchul; Shin, Sang Yong

    2016-06-01

    The correlation between the microstructures and tensile properties of strain-based American Petroleum Institute (API) X60 pipeline steels was investigated. Eight types of strain-based API X60 pipeline steels were fabricated by varying the chemical compositions, such as C, Ni, Cr, and Mo, and the finish cooling temperatures, such as single-phase and dual-phase regions. In the 4N and 5C steels, the volume fractions of bainitic ferrite (BF) and the secondary phases increased with the increasing C and adding Cr instead of Ni. In the 5C and 6NC steels, the volume fractions of acicular ferrite (AF) and BF decreased with increasing C and adding Ni, whereas the volume fractions of polygonal ferrite (PF) and the secondary phases increased. In the 6NC and 6NM steels, the volume fraction of BF was increased by adding Mo instead of Cr, whereas the volume fractions of PF and the secondary phases decreased. In the steels rolled in the single-phase region, the volume fraction of polygonal ferrite ranged from 40 to 60 pct and the volume fraction of AF ranged from 20 to 40 pct. In the steels rolled in the dual-phase region, however, the volume fraction of PF was more than 70 pct and the volume fraction of AF was below 20 pct. The strength of the steels with a high volume fraction of AF was higher than those of the steels with a high volume fraction of PF, whereas the yield point elongation and the strain hardening exponent were opposite. The uniform elongation after the thermal aging process decreased with increasing volume fraction of PF, whereas the uniform elongation increased with increasing volume fraction of AF. The strain hardening exponent increased with increasing volume fraction of PF, but decreased with increasing volume fraction of AF and effective grain size.

  3. An interactive physics-based unmanned ground vehicle simulator leveraging open source gaming technology: progress in the development and application of the virtual autonomous navigation environment (VANE) desktop

    Science.gov (United States)

    Rohde, Mitchell M.; Crawford, Justin; Toschlog, Matthew; Iagnemma, Karl D.; Kewlani, Guarav; Cummins, Christopher L.; Jones, Randolph A.; Horner, David A.

    2009-05-01

    It is widely recognized that simulation is pivotal to vehicle development, whether manned or unmanned. There are few dedicated choices, however, for those wishing to perform realistic, end-to-end simulations of unmanned ground vehicles (UGVs). The Virtual Autonomous Navigation Environment (VANE), under development by US Army Engineer Research and Development Center (ERDC), provides such capabilities but utilizes a High Performance Computing (HPC) Computational Testbed (CTB) and is not intended for on-line, real-time performance. A product of the VANE HPC research is a real-time desktop simulation application under development by the authors that provides a portal into the HPC environment as well as interaction with wider-scope semi-automated force simulations (e.g. OneSAF). This VANE desktop application, dubbed the Autonomous Navigation Virtual Environment Laboratory (ANVEL), enables analysis and testing of autonomous vehicle dynamics and terrain/obstacle interaction in real-time with the capability to interact within the HPC constructive geo-environmental CTB for high fidelity sensor evaluations. ANVEL leverages rigorous physics-based vehicle and vehicle-terrain interaction models in conjunction with high-quality, multimedia visualization techniques to form an intuitive, accurate engineering tool. The system provides an adaptable and customizable simulation platform that allows developers a controlled, repeatable testbed for advanced simulations. ANVEL leverages several key technologies not common to traditional engineering simulators, including techniques from the commercial video-game industry. These enable ANVEL to run on inexpensive commercial, off-the-shelf (COTS) hardware. In this paper, the authors describe key aspects of ANVEL and its development, as well as several initial applications of the system.

  4. Comparison of ground based indices (API and AQI) with satellite based aerosol products.

    Science.gov (United States)

    Zheng, Sheng; Cao, Chun-Xiang; Singh, Ramesh P

    2014-08-01

    Air quality in mega cities is one of the major concerns due to serious health issues and its indirect impact to the climate. Among mega cities, Beijing city is considered as one of the densely populated cities with extremely poor air quality. The meteorological parameters (wind, surface temperature, air temperature and relative humidity) control the dynamics and dispersion of air pollution. China National Environmental Monitoring Centre (CNEMC) started air pollution index (API) as of 2000 to evaluate air quality, but over the years, it was felt that the air quality is not well represented by API. Recently, the Ministry of Environmental Protection (MEP) of the People's Republic of China (PRC) started using a new index "air quality index (AQI)" from January 2013. We have compared API and AQI with three different MODIS (MODIS - Moderate Resolution Imaging SpectroRadiometer, onboard the Terra/Aqua satellites) AOD (aerosol optical depth) products for ten months, January-October, 2013. The correlation between AQI and Aqua Deep Blue AOD was found to be reasonably good as compared with API, mainly due to inclusion of PM2.5 in the calculation of AQI. In addition, for every month, the correlation coefficient between AQI and Aqua Deep Blue AOD was found to be relatively higher in the month of February to May. According to the monthly average distribution of precipitation, temperature, and PM10, the air quality in the months of June-September was better as compared to those in the months of February-May. AQI and Aqua Deep Blue AOD show highly polluted days associated with dust event, representing true air quality of Beijing.

  5. 基于API依赖关系的代码相似度分析%Code Similarity Analysis Based on API Dependence Relation

    Institute of Scientific and Technical Information of China (English)

    姚新磊; 庞建民; 岳峰; 余勇

    2013-01-01

    Aiming at the problem of API feature obfuscation caused by API noise and API rearrangement which traditional System Call Dependence Graph(SCDG) can not eliminate, this paper presents a malicious code similarity analysis method based on API dependence. The method uses a program behavior description based on SCDG composed of control dependence and four types of data dependence between APIs. API noise and API rearrangement are eliminated through data dependence analysis and control dependence normalization. Experimental results show that, compared with API sequence similarity analysis method, this method significantly improves the accuracy of the similarity analysis of malicious code.%针对传统系统调用依赖图(SCDG)不能很好地消除API噪声、API重排等API特征混淆的问题,提出一种基于API依赖关系的恶意代码相似度分析方法.采用由API控制依赖关系和4类数据依赖关系组成的SCDG程序行为描述方式,通过数据依赖关系分析和控制依赖关系归一化,消除SCDG中的API噪声和API重排.实验结果表明,与API序列相似度分析方式相比,该方法能提高恶意代码相似度分析的准确性.

  6. Genetic structure of Apis mellifera macedonica in the Balkan Peninsula based on microsatellite DNA polymorphism

    DEFF Research Database (Denmark)

    Uzunov, Aleksandar; Meixner, Marina D; Kiprijanovska, Hrisula;

    2014-01-01

    The genetic variability of honey bees (Apis mellifera L.) from south eastern Europe was investigated using microsatellite analyses of 107 samples from Albania, the Republic of Macedonia, Greece and Bulgaria together with 42 reference samples (Apis mellifera carnica) from Slovenia. Genetic structure...... and spatial analyses of the microsatellite data showed a clear distinction between the Slovenian bees and all other populations, and confirmed the existence of Apis mellifera macedonica as an indigenous honey bee population in the regions that were sampled. In most areas however, varying degrees...

  7. USAJOBS Job Opportunity Announcements (JOA) SOAP API

    Data.gov (United States)

    Office of Personnel Management — The purpose of the SOAP based API is to provide the full Federal Job Opportunity Announcement (JOA) content to the consumer. It is anticipated that this API will be...

  8. USAJOBS Job Opportunity Announcements (JOA) REST API

    Data.gov (United States)

    Office of Personnel Management — This REST-based API is designed to support lightweight Federal Job Opportunity Announcement (JOA) content consumption by consumers. It is anticipated that this API...

  9. Research on API Based on Visual Programming Platforms%基于可视化平台的 API 接口研究

    Institute of Scientific and Technical Information of China (English)

    关玉蓉

    2015-01-01

    In a variety of visual programming platforms, especially with the external network environment, , a large number of API functions under Windows can help reflect strong advanced programming skills proving to be a multiplier effect. This paper firstly introduces the API function and the dynamic link library DLL, then briefly ex-plains the classification of API functions, and focuses on how to call the API function and its application of API function in the visual platform. The paper finally describes the skills and notes to pay attention for users when call-ing the API function, which enables them to master the advanced programming skills of API interface.%在各种可视化编程平台中,尤其是与外部网络环境相结合,为了体现强大的高级编程能力,可用Windows系统提供的大量API函数,必然会起到事半功倍的效果。本文首先介绍了API函数以及动态链接库DLL,其次简要说明了API函数的分类,然后重点分析了在可视化平台中如何调用API函数及其应用API函数的高级编程能力,最后阐述了用户调用API函数的技巧和注意事项,以提高用户灵活掌握API接口的高级编程应用能力。

  10. 3D Reconstruction of Desktop of Table Tennis Based on the Binocular Vision%双目视觉的台球桌面的三维重构

    Institute of Scientific and Technical Information of China (English)

    张旭飞; 王朝立; 袁伟

    2013-01-01

    At present, with the rapid development of the computer technologies which has grown dramatically, and there are more and more sports competition where some high and new technologies are emploited as the electronic referee to assist referee to do the decisions, in order to achieve the spirit of fair play which respected by Olympic. During this process, the camera plays an important role in computer vision. 3D reconstruction is a process based on a single view or multi-view images to obtain the 3D information in the field of computer vision. In this paper, in order to complete a task about three-dimensional reconstruction of desktop of Table tennis, we take 3D reconstruction technologies in computer vision as the mainly research object, including specific details about the theoretical knowledge on the binocular vision and the reconstruction algorithm provided by the computer vision library OpenCV. The 3D reconstruction of billiards desktop have strong practical significance, which laid a good foundation for the electronic referee to work in the billiards competition.%  随着计算机技术的迅猛发展,在越来越多的体育比赛中纷纷出现了电子裁判来辅助裁判进行判罚工作,以实现奥林匹克的公平竞赛精神。而在实现这种数字化裁判的过程中,摄像机在计算机视觉中起着重要的作用,三维重构就是根据单视图或者多视图的图像重建三维信息的过程。主要以计算机视觉中的三维重构技术作为研究对象,具体详述了有关双目视觉的一些理论知识,充分利用计算机视觉库OpenCV提供的重建算法,来完成对台球桌面的三维重构工作。台球桌面的三维重构具有很强的现实意义,为电子裁判进入桌球比赛打下了良好的基础。

  11. Building Hypermedia APIs with HTML5 and Node

    CERN Document Server

    Amundsen, Mike

    2011-01-01

    With this concise book, you'll learn the art of building hypermedia APIs that don't simply run on the Web, but that actually exist in the Web. You'll start with the general principles and technologies behind this architectural approach, and then dive hands-on into three fully-functional API examples. Too many APIs rely on concepts rooted in desktop and local area network patterns that don't scale well-costly solutions that are difficult to maintain over time. This book shows system architects and web developers how to design and implement human- and machine-readable web services that remain

  12. Design and Implementation of Surrounding Transaction Plotting and Management System Based on Google Map API

    Science.gov (United States)

    Cao, Y. B.; Hua, Y. X.; Zhao, J. X.; Guo, S. M.

    2013-11-01

    With China's rapid economic development and comprehensive national strength growing, Border work has become a long-term and important task in China's diplomatic work. How to implement rapid plotting, real-time sharing and mapping surrounding affairs has taken great significance for government policy makers and diplomatic staff. However, at present the already exists Boundary information system are mainly have problems of Geospatial data update is heavily workload, plotting tools are in a state of serious lack of, Geographic events are difficult to share, this phenomenon has seriously hampered the smooth development of the border task. The development and progress of Geographic information system technology especially the development of Web GIS offers the possibility to solve the above problems, this paper adopts four layers of B/S architecture, with the support of Google maps service, uses the free API which is offered by Google maps and its features of openness, ease of use, sharing characteristics, highresolution images to design and implement the surrounding transaction plotting and management system based on the web development technology of ASP.NET, C#, Ajax. The system can provide decision support for government policy makers as well as diplomatic staff's real-time plotting and sharing of surrounding information. The practice has proved that the system has good usability and strong real-time.

  13. Contracting the Facebook API

    Directory of Open Access Journals (Sweden)

    Ben Rubinger

    2010-09-01

    Full Text Available In recent years, there has been an explosive growth in the popularity of online social networks such as Facebook. In a new twist, third party developers are now able to create their own web applications which plug into Facebook and work with Facebook's "social" data, enabling the entire Facebook user base of more than 400 million active users to use such applications. These client applications can contain subtle errors that can be hard to debug if they misuse the Facebook API. In this paper we present an experience report on applying Microsoft's new code contract system for the .NET framework to the Facebook API.We wrote contracts for several classes in the Facebook API wrapper which allows Microsoft .NET developers to implement Facebook applications. We evaluated the usefulness of these contracts during implementation of a new Facebook application. Our experience indicates that having code contracts provides a better and quicker software development experience.

  14. From WSN towards WoT: Open API Scheme Based on oneM2M Platforms

    Directory of Open Access Journals (Sweden)

    Jaeho Kim

    2016-10-01

    Full Text Available Conventional computing systems have been able to be integrated into daily objects and connected to each other due to advances in computing and network technologies, such as wireless sensor networks (WSNs, forming a global network infrastructure, called the Internet of Things (IoT. To support the interconnection and interoperability between heterogeneous IoT systems, the availability of standardized, open application programming interfaces (APIs is one of the key features of common software platforms for IoT devices, gateways, and servers. In this paper, we present a standardized way of extending previously-existing WSNs towards IoT systems, building the world of the Web of Things (WoT. Based on the oneM2M software platforms developed in the previous project, we introduce a well-designed open API scheme and device-specific thing adaptation software (TAS enabling WSN elements, such as a wireless sensor node, to be accessed in a standardized way on a global scale. Three pilot services are implemented (i.e., a WiFi-enabled smart flowerpot, voice-based control for ZigBee-connected home appliances, and WiFi-connected AR.Drone control to demonstrate the practical usability of the open API scheme and TAS modules. Full details on the method of integrating WSN elements into three example systems are described at the programming code level, which is expected to help future researchers in integrating their WSN systems in IoT platforms, such as oneM2M. We hope that the flexibly-deployable, easily-reusable common open API scheme and TAS-based integration method working with the oneM2M platforms will help the conventional WSNs in diverse industries evolve into the emerging WoT solutions.

  15. From WSN towards WoT: Open API Scheme Based on oneM2M Platforms.

    Science.gov (United States)

    Kim, Jaeho; Choi, Sung-Chan; Ahn, Il-Yeup; Sung, Nak-Myoung; Yun, Jaeseok

    2016-10-06

    Conventional computing systems have been able to be integrated into daily objects and connected to each other due to advances in computing and network technologies, such as wireless sensor networks (WSNs), forming a global network infrastructure, called the Internet of Things (IoT). To support the interconnection and interoperability between heterogeneous IoT systems, the availability of standardized, open application programming interfaces (APIs) is one of the key features of common software platforms for IoT devices, gateways, and servers. In this paper, we present a standardized way of extending previously-existing WSNs towards IoT systems, building the world of the Web of Things (WoT). Based on the oneM2M software platforms developed in the previous project, we introduce a well-designed open API scheme and device-specific thing adaptation software (TAS) enabling WSN elements, such as a wireless sensor node, to be accessed in a standardized way on a global scale. Three pilot services are implemented (i.e., a WiFi-enabled smart flowerpot, voice-based control for ZigBee-connected home appliances, and WiFi-connected AR.Drone control) to demonstrate the practical usability of the open API scheme and TAS modules. Full details on the method of integrating WSN elements into three example systems are described at the programming code level, which is expected to help future researchers in integrating their WSN systems in IoT platforms, such as oneM2M. We hope that the flexibly-deployable, easily-reusable common open API scheme and TAS-based integration method working with the oneM2M platforms will help the conventional WSNs in diverse industries evolve into the emerging WoT solutions.

  16. From WSN towards WoT: Open API Scheme Based on oneM2M Platforms

    Science.gov (United States)

    Kim, Jaeho; Choi, Sung-Chan; Ahn, Il-Yeup; Sung, Nak-Myoung; Yun, Jaeseok

    2016-01-01

    Conventional computing systems have been able to be integrated into daily objects and connected to each other due to advances in computing and network technologies, such as wireless sensor networks (WSNs), forming a global network infrastructure, called the Internet of Things (IoT). To support the interconnection and interoperability between heterogeneous IoT systems, the availability of standardized, open application programming interfaces (APIs) is one of the key features of common software platforms for IoT devices, gateways, and servers. In this paper, we present a standardized way of extending previously-existing WSNs towards IoT systems, building the world of the Web of Things (WoT). Based on the oneM2M software platforms developed in the previous project, we introduce a well-designed open API scheme and device-specific thing adaptation software (TAS) enabling WSN elements, such as a wireless sensor node, to be accessed in a standardized way on a global scale. Three pilot services are implemented (i.e., a WiFi-enabled smart flowerpot, voice-based control for ZigBee-connected home appliances, and WiFi-connected AR.Drone control) to demonstrate the practical usability of the open API scheme and TAS modules. Full details on the method of integrating WSN elements into three example systems are described at the programming code level, which is expected to help future researchers in integrating their WSN systems in IoT platforms, such as oneM2M. We hope that the flexibly-deployable, easily-reusable common open API scheme and TAS-based integration method working with the oneM2M platforms will help the conventional WSNs in diverse industries evolve into the emerging WoT solutions. PMID:27782058

  17. The SEMAINE API: Towards a Standards-Based Framework for Building Emotion-Oriented Systems

    Directory of Open Access Journals (Sweden)

    Marc Schröder

    2010-01-01

    Full Text Available This paper presents the SEMAINE API, an open source framework for building emotion-oriented systems. By encouraging and simplifying the use of standard representation formats, the framework aims to contribute to interoperability and reuse of system components in the research community. By providing a Java and C++ wrapper around a message-oriented middleware, the API makes it easy to integrate components running on different operating systems and written in different programming languages. The SEMAINE system 1.0 is presented as an example of a full-scale system built on top of the SEMAINE API. Three small example systems are described in detail to illustrate how integration between existing and new components is realised with minimal effort.

  18. Pathway projector: web-based zoomable pathway browser using KEGG atlas and Google Maps API.

    Directory of Open Access Journals (Sweden)

    Nobuaki Kono

    Full Text Available BACKGROUND: Biochemical pathways provide an essential context for understanding comprehensive experimental data and the systematic workings of a cell. Therefore, the availability of online pathway browsers will facilitate post-genomic research, just as genome browsers have contributed to genomics. Many pathway maps have been provided online as part of public pathway databases. Most of these maps, however, function as the gateway interface to a specific database, and the comprehensiveness of their represented entities, data mapping capabilities, and user interfaces are not always sufficient for generic usage. METHODOLOGY/PRINCIPAL FINDINGS: We have identified five central requirements for a pathway browser: (1 availability of large integrated maps showing genes, enzymes, and metabolites; (2 comprehensive search features and data access; (3 data mapping for transcriptomic, proteomic, and metabolomic experiments, as well as the ability to edit and annotate pathway maps; (4 easy exchange of pathway data; and (5 intuitive user experience without the requirement for installation and regular maintenance. According to these requirements, we have evaluated existing pathway databases and tools and implemented a web-based pathway browser named Pathway Projector as a solution. CONCLUSIONS/SIGNIFICANCE: Pathway Projector provides integrated pathway maps that are based upon the KEGG Atlas, with the addition of nodes for genes and enzymes, and is implemented as a scalable, zoomable map utilizing the Google Maps API. Users can search pathway-related data using keywords, molecular weights, nucleotide sequences, and amino acid sequences, or as possible routes between compounds. In addition, experimental data from transcriptomic, proteomic, and metabolomic analyses can be readily mapped. Pathway Projector is freely available for academic users at (http://www.g-language.org/PathwayProjector/.

  19. 基于SOA的SLE API系统设计%Design of an SOA-based SLE API Svstem

    Institute of Scientific and Technical Information of China (English)

    王喆; 鲍忠贵; 高三红; 苑刚

    2011-01-01

    介绍了CCSDS(空间数据系统咨询委员会)标准下的SLE(空间链路扩展)系统中API(应用程序接口)系统的概念和模型,并基于SOA(面向服务的体系结构)思想深入分析了SLE API系统的设计模式.SOA模型具有松耦合、重用性高、扩展性强等特点,这与我国提出的建立系统间“互联、互通、互操作”的新一代测控网的目标相吻合.本文在SOA模型框架下,针对我国测控网的现状,提出新型测控网可能的发展方向.%This paper introduces the concept and model of SLE API (Space Link Extension Application Program Interface) systems in CCSDS recommendations and analyzes SLE API system design based on SOA (Service Oriented Architecture). SOA model has the characteristics of loose coupling, great reusability and scalability. These are consistent with the interconnectivity and interoperability objectives of China's next generation TT&-C networks. Furthermore, the paper puts forward a probable approach for a new TT&.C management system.

  20. Drug Interaction API

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Interaction API is a web service for accessing drug-drug interactions. No license is needed to use the Interaction API. Currently, the API uses DrugBank for its...

  1. 基于KVM虚拟桌面的透明消息通道设计%Design of Transparent Message Channel Based on KVM Virtual Desktop

    Institute of Scientific and Technical Information of China (English)

    崔竞松; 何松; 郭迟; 贺汇林

    2014-01-01

    Cloud management platform and end-users of virtual machine generally use proxy software or plug-ins to communicate with each other,but the convenience and anti-jamming capabilities of this method is poor. Aiming at this problem ,this paper proposes a design scheme for transparent message channel between the node provided by cloud service ( the physical host that virtual machine lies in) and the end-user of virtual machine based on virtual desktop on Kernel-based Virtual Machine( KVM) . It builds message control terminal in cloud management platform to receive and process messages that service node sends to end-users of virtual machine, and transforms the messages into images, reads the content of images into specified file in the form of bitmap pixel data as the source of message sending module. It adds message sending module and feedback receiving module into source codes by modifying the source code of Virtual Network Computing ( VNC ) server-side integrated by Qemu-KVM of KVM virtualization platform, integrates the messages into desktop image of the virtual machine,and processes the feedback from the remote terminal of VCN client. Then it builds a two-way interactive message channel between the cloud platform and the end-users which is transparent for virtual machine itself. Experimental result verifies that this scheme is feasible.%云管理平台和虚拟机终端用户间的通信一般采用代理软件或插件,便捷性和抗干扰能力较低。针对该问题,利用基于内核的虚拟机( KVM)虚拟桌面,提出一种云服务提供节点(虚拟机所在物理主机)和虚拟机终端用户之间双向交互的透明消息通道设计方案。在云管理平台中建立消息控制端,用于接收和处理服务节点发往虚拟机终端用户的消息,并将消息转换为图像,使图像内容以位图像素数据格式的方式读出到特定文件中,作为消息发送模块的消息来源。通过修改KVM虚

  2. Corrosion resistance of ERW (Electric Resistance Welded) seam welds as compared to metal base in API 5L steel pipes

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez Velasquez, Jorge L.; Godinez Salcedo, Jesus G.; Lopez Fajardo, Pedro [Instituto Politecnico Nacional (IPN), Mexico D.F. (Mexico). Escuela Superior de Ingenieria Quimica e Industrias Extractivas (ESIQIE). Dept. de Ingenieria Metalurgica

    2009-07-01

    The corrosion resistance of ERW seam welds and the base metal in API 5L X70 steel pipes was evaluated by Tafel tests. The procedure was according to ASTM G3 standard. The study was completed with metallographic and chemical characterization of the tested zones, that is, the welded zone and the base metal away of the weld. All tests were made on the internal surface of the pipe in order to assess the internal corrosion of an in-service pipeline made of the API 5L X70 steel. The test solution was acid brine prepared according to NACE Publications 1D182 and 1D196. The results showed that the ERW seam weld corrodes as much as three times faster than the base material. This behavior is attributed to a more heterogeneous microstructure with higher internal energy in the ERW seam weld zone, as compared to the base metal, which is basically a ferrite pearlite microstructure in a normalized condition. This result also indicates that pipeline segments made of ERW steel pipe where the seam weld is located near or at the bottom of the pipe are prone to a highly localized attack that may form channels of metal loss if there is water accumulation at the bottom of the pipeline. (author)

  3. Study of an API migration for two XML APIs

    NARCIS (Netherlands)

    Bartholomei, T.T.; Czarnecki, K.; Lämmel, R.; Storm, T. van der; Brand, M.G.J. van den; Gasevic, D.; Gray, J.

    2010-01-01

    API migration refers to adapting an application such that its dependence on a given API (the source API) is eliminated in favor of depending on an alternative API (the target API) with the source and target APIs serving the same domain. One may attempt to automate API migration by code transformatio

  4. Desktop calibration of automatic transmission for passenger vehicle

    Institute of Scientific and Technical Information of China (English)

    FANG Chi; SHI Jian-peng; WANG Jun

    2014-01-01

    Desktop calibration of automatic transmission (AT) is a method which can reduce cost, enhance efficiency and shorten the development periods of a vehicle effectively. We primary introduced the principle and approach of desktop calibration of AT based on the condition of coupling characteristics between engine and torque converter and obtained right point exactly. It is shown to agree with experimental measurements reasonably well. It was used in different applications abroad based on AT technology and achieved a good performance of the vehicle compared with traditional AT technology which primary focuses on the drivability, performance and fuel consumption.

  5. Scaling Critical Zone analysis tasks from desktop to the cloud utilizing contemporary distributed computing and data management approaches: A case study for project based learning of Cyberinfrastructure concepts

    Science.gov (United States)

    Swetnam, T. L.; Pelletier, J. D.; Merchant, N.; Callahan, N.; Lyons, E.

    2015-12-01

    Earth science is making rapid advances through effective utilization of large-scale data repositories such as aerial LiDAR and access to NSF-funded cyberinfrastructures (e.g. the OpenTopography.org data portal, iPlant Collaborative, and XSEDE). Scaling analysis tasks that are traditionally developed using desktops, laptops or computing clusters to effectively leverage national and regional scale cyberinfrastructure pose unique challenges and barriers to adoption. To address some of these challenges in Fall 2014 an 'Applied Cyberinfrastructure Concepts' a project-based learning course (ISTA 420/520) at the University of Arizona focused on developing scalable models of 'Effective Energy and Mass Transfer' (EEMT, MJ m-2 yr-1) for use by the NSF Critical Zone Observatories (CZO) project. EEMT is a quantitative measure of the flux of available energy to the critical zone, and its computation involves inputs that have broad applicability (e.g. solar insolation). The course comprised of 25 students with varying level of computational skills and with no prior domain background in the geosciences, collaborated with domain experts to develop the scalable workflow. The original workflow relying on open-source QGIS platform on a laptop was scaled to effectively utilize cloud environments (Openstack), UA Campus HPC systems, iRODS, and other XSEDE and OSG resources. The project utilizes public data, e.g. DEMs produced by OpenTopography.org and climate data from Daymet, which are processed using GDAL, GRASS and SAGA and the Makeflow and Work-queue task management software packages. Students were placed into collaborative groups to develop the separate aspects of the project. They were allowed to change teams, alter workflows, and design and develop novel code. The students were able to identify all necessary dependencies, recompile source onto the target execution platforms, and demonstrate a functional workflow, which was further improved upon by one of the group leaders over

  6. Construction of Experiment Teaching Platform Based on the Cloud Desktop%基于桌面云的实验教学平台的构建

    Institute of Scientific and Technical Information of China (English)

    郭芬; 李静锴; 张安定

    2015-01-01

    本科实验教学课程是本科教学的重要组成部分,传统实验教学中心的模式已不能适应计算机软件专业的发展和需求。本文针对传统实验教学平台存在的问题,充分利用桌面云技术的优势,构建基于桌面云的实验教学平台。该平台面向实验教学过程的各个环节,涉及到实验室的管理、学生上机实验的考勤和管理、实验教学镜像的制作、服务器集群的监控等过程。学生可通过本文构建的桌面云实验教学平台按需自助的通过云终端获取实验资源,从而最大化满足学生对学习资源的需求。同时该平台有利于教师教学资源及教学成果的共享,从而提高实验教学的质量,促进学院学科建设的发展。%Experimental teaching is very important for university teaching, and the traditional experiment teaching mode can not adapt to the development of computer software. An teaching platform for experiment is constructed, which is based on the cloud desktop. The platform takes each factor for experiment teaching into account, involving the management of laboratory, attendance of students, setting up of environment image, and server cluster monitoring, etc. The experiment teaching platform can meet the needs of students in learning resources as best as it can, students can access to the resources on-demand self-service via cloud terminal. At the same time, it is beneficial for teaching resources sharing so as to improve the quality of experiment teaching.

  7. Scheduling in Desktop Grid Systems: Theoretical Evaluation of Policies & Frameworks

    Directory of Open Access Journals (Sweden)

    Muhammad Khalid Khan

    2017-01-01

    Full Text Available Desktop grid systems have already established their identity in the area of distributed systems. They are well suited for High Throughput Computing especially for Bag-of-Tasks applications. In desktop grid systems, idle processing cycles and memory of millions of users (connected through internet or through any other communication mechanism can be utilized but the workers / hosts machines not under any centralized administrative control that result in high volatility. This issue is countered by applying various types of scheduling policies that not only ensure task assignments to better workers but also takes care of fault tolerance through replication and other mechanism. In this paper, we discussed leading desktop grid systems framework and performed a comparative analysis of these frameworks. We also presented a theoretical evaluation of server and client based scheduling policies and identified key performance indicators to evaluate these policies.

  8. Bridging the Gap between Linked Data and the Semantic Desktop

    Science.gov (United States)

    Groza, Tudor; Drăgan, Laura; Handschuh, Siegfried; Decker, Stefan

    The exponential growth of the World Wide Web in the last decade brought an explosion in the information space, which has important consequences also in the area of scientific research. Finding relevant work in a particular field and exploring the links between publications is currently a cumbersome task. Similarly, on the desktop, managing the publications acquired over time can represent a real challenge. Extracting semantic metadata, exploring the linked data cloud and using the semantic desktop for managing personal information represent, in part, solutions for different aspects of the above mentioned issues. In this paper, we propose an innovative approach for bridging these three directions with the overall goal of alleviating the information overload problem burdening early stage researchers. Our application combines harmoniously document engineering-oriented automatic metadata extraction with information expansion and visualization based on linked data, while the resulting documents can be seamlessly integrated into the semantic desktop.

  9. Three Dimensional Visualization of DWG Data Based on ArcGIS for Desktop%基于 ArcGIS for Desktop 的 DWG 数据三维可视化应用

    Institute of Scientific and Technical Information of China (English)

    陈晓辉; 马丽霞; 李丹丹

    2014-01-01

    ArcScene in ArcGIS can produce a better 3D effect in the application.With three-dimension-al visualization of DWG data based on ArcGIS,this paper focuses on the 3D visualization,and elaborate on the procedure and principle of 3D visualization system.%ArcGIS中ArcScene在应用中可更好地表达图形的3D效果,基于ArcGIS for Desktop的DWG数据三维可视化,对社会的发展具有重要的推动作用。文章针对三维可视化系统进行了分析和研究,阐述了其步骤和原理。

  10. Accessing Inaccessible Android APIs: An Empirical Study

    OpenAIRE

    Li, LI; Bissyande, Tegawendé François D Assise; Le Traon, Yves; Klein, Jacques

    2016-01-01

    As Android becomes a de-facto choice of development platform for mobile apps, developers extensively leverage its accompanying Software Development Kit to quickly build their apps. This SDK comes with a set of APIs which developers may find limited in comparison to what system apps can do or what framework developers are preparing to harness capabilities of new generation devices. Thus, developers may attempt to explore in advance the normally “inaccessible” APIs for building unique API-based...

  11. Analyzing the Change-Proneness of APIs and web APIs

    NARCIS (Netherlands)

    Romano, D.

    2015-01-01

    Analyzing the Change-Proneness of APIs and web APIs APIs and web APIs are used to expose existing business logic and, hence, to ease the reuse of functionalities across multiple software systems. Software systems can use the business logic of legacy systems by binding their APIs and web APIs. With t

  12. Instant Citrix XenDesktop 5 starter

    CERN Document Server

    Magdy, Mahmoud

    2013-01-01

    Get to grips with a new technology, understand what it is and what it can do for you, and then get to work with the most important features and tasks. This easy-to-follow, hands-on guide shows you how to implement desktop virtualization with real life cases and step-by-step instructions. It is a tutorial with step-by-step instructions and adequate screenshots for the installation and administration of Citrix XenDesktop.If you are new to XenDesktop or are looking to build your skills in desktop virtualization, this is your step-by-step guide to learning Citrix XenDesktop. For those architects a

  13. Healthcare Finder API

    Data.gov (United States)

    U.S. Department of Health & Human Services — All of the data used on the Finder.HealthCare.gov web application is available through this API. There are multiple collections of data available through the API. 1....

  14. NASA Techport API

    Data.gov (United States)

    National Aeronautics and Space Administration — The NASA TechPort system provides a RESTful web services API to make technology project data available in a machine-readable format. This API can be used to export...

  15. Effects of Finish Cooling Temperature on Tensile Properties After Thermal Aging of Strain-Based API X60 Linepipe Steels

    Science.gov (United States)

    Sung, Hyo Kyung; Lee, Dong Ho; Shin, Sang Yong; Lee, Sunghak; Ro, Yunjo; Lee, Chang Sun; Hwang, Byoungchul

    2015-09-01

    Two types of strain-based American Petroleum Institute (API) X60 linepipe steels were fabricated at two finish cooling temperatures, 673 K and 723 K (400 °C and 450 °C), and the effects of the finish cooling temperatures on the tensile properties after thermal aging were investigated. The strain-based API X60 linepipe steels consisted mainly of polygonal ferrite (PF) or quasi-polygonal ferrite and the volume fraction of acicular ferrite increased with the increasing finish cooling temperature. In contrast, the volume fractions of bainitic ferrite (BF) and secondary phases decreased. The tensile properties before and after thermal aging at 473 K and 523 K (200 °C and 250 °C) were measured. The yield strength, ultimate tensile strength, and yield ratio increased with the increasing thermal aging temperature. The strain hardening rate in the steel fabricated at the higher finish cooling temperature decreased rapidly after thermal aging, probably due to the Cottrell atmosphere, whereas the strain hardening rate in the steel fabricated at the lower finish cooling temperature changed slightly after thermal aging. The uniform elongation and total elongation decreased with increasing thermal aging temperature, probably due to the interactions between carbon atoms and dislocations. The uniform elongation decreased rapidly with the decreasing volume fractions of BF and martensite and secondary phases. The yield ratio increased with the increasing thermal aging temperature, whereas the strain hardening exponent decreased. The strain hardening exponent of PL steel decreased rapidly after thermal aging because of the large number of mobile dislocations between PF and BF or martensite or secondary phases.

  16. Cloud Desktop Construction Based on Hyper-V Technology%基于Hyper-V技术的云桌面构建

    Institute of Scientific and Technical Information of China (English)

    卞昌军

    2015-01-01

    文章在分析现有高职院校实验室的发展现状与存在问题的基础上,给出一种利用Hyper-V技术对服务器群集进行虚拟化,从而构建实验室云桌面的方法,并已经在实验室中进行详细部署实现。%The paper proposes a method using Hyper-V technology to virtualize the server clusters,and constructs the laboratory cloud desktop after analyzing the current situation and problems in the development of laboratory of vocational colleges.And then it is realized in the laboratory by using the method above.

  17. GREEN SUPERCOMPUTING IN A DESKTOP BOX

    Energy Technology Data Exchange (ETDEWEB)

    HSU, CHUNG-HSING [Los Alamos National Laboratory; FENG, WU-CHUN [NON LANL; CHING, AVERY [NON LANL

    2007-01-17

    The computer workstation, introduced by Sun Microsystems in 1982, was the tool of choice for scientists and engineers as an interactive computing environment for the development of scientific codes. However, by the mid-1990s, the performance of workstations began to lag behind high-end commodity PCs. This, coupled with the disappearance of BSD-based operating systems in workstations and the emergence of Linux as an open-source operating system for PCs, arguably led to the demise of the workstation as we knew it. Around the same time, computational scientists started to leverage PCs running Linux to create a commodity-based (Beowulf) cluster that provided dedicated computer cycles, i.e., supercomputing for the rest of us, as a cost-effective alternative to large supercomputers, i.e., supercomputing for the few. However, as the cluster movement has matured, with respect to cluster hardware and open-source software, these clusters have become much more like their large-scale supercomputing brethren - a shared (and power-hungry) datacenter resource that must reside in a machine-cooled room in order to operate properly. Consequently, the above observations, when coupled with the ever-increasing performance gap between the PC and cluster supercomputer, provide the motivation for a 'green' desktop supercomputer - a turnkey solution that provides an interactive and parallel computing environment with the approximate form factor of a Sun SPARCstation 1 'pizza box' workstation. In this paper, they present the hardware and software architecture of such a solution as well as its prowess as a developmental platform for parallel codes. In short, imagine a 12-node personal desktop supercomputer that achieves 14 Gflops on Linpack but sips only 185 watts of power at load, resulting in a performance-power ratio that is over 300% better than their reference SMP platform.

  18. Contracting the Facebook API

    OpenAIRE

    2010-01-01

    In recent years, there has been an explosive growth in the popularity of online social networks such as Facebook. In a new twist, third party developers are now able to create their own web applications which plug into Facebook and work with Facebook's "social" data, enabling the entire Facebook user base of more than 400 million active users to use such applications. These client applications can contain subtle errors that can be hard to debug if they misuse the Facebook API. In this paper w...

  19. Android quick APIs reference

    CERN Document Server

    Cinar, Onur

    2015-01-01

    The Android Quick APIs Reference is a condensed code and APIs reference for the new Google Android 5.0 SDK. It presents the essential Android APIs in a well-organized format that can be used as a handy reference. You won't find any technical jargon, bloated samples, drawn out history lessons, or witty stories in this book. What you will find is a software development kit and APIs reference that is concise, to the point and highly accessible. The book is packed with useful information and is a must-have for any mobile or Android app developer or programmer. In the Android Quick APIs Refe

  20. Development of a GIS-Based Online Discussion System for Scientists with Google Earth API and Twitter

    Science.gov (United States)

    Ohtake, S.; Demura, H.; Hirata, N.; Terazono, J.

    2011-03-01

    This study has developed an online discussion system cooperating with GIS for researchers in planetary sciences. We focused on mushup approach with the existing web services; Google Earth API and Twitter.

  1. Selecting the Right Camera for Your Desktop.

    Science.gov (United States)

    Rhodes, John

    1997-01-01

    Provides an overview of camera options and selection criteria for desktop videoconferencing. Key factors in image quality are discussed, including lighting, resolution, and signal-to-noise ratio; and steps to improve image quality are suggested. (LRW)

  2. Desktop Virtualization Solutions-A Comprehensive Survey

    Directory of Open Access Journals (Sweden)

    Vasuprada Vijayakumar

    2013-09-01

    Full Text Available Virtualization has become apparent in the 1960s as a practice to enhance the use of expensive computing hardware. Virtualization targets to reduce the complexity associated with deployment and maintenance of client devices, which eventually helps IT Companies to reduce system management costs. In this paper, we propose the virtualization concept expanding into many aspects of IT world. There are various virtualization technologies which include storage, desktop virtual platforms, server consolidation, virtual desktop infrastructure and application virtualization. This is the basic prerequisite for cloud computing and its applications. This paper highlights the benefits of virtualization and provides a comparative study on the various products that have been derived from it. This paper also describes how to create a virtualization strategy introducing comprehensive desktop-virtualization solutions, thereby providing a high-level guidance to help develop a desktop-virtualization strategy.

  3. 桌面虚拟现实技术在医学多媒体课件中的设计与应用%Design and application of desktop-based virtual reality technology in medical multimedia courseware

    Institute of Scientific and Technical Information of China (English)

    孙项洁; 卞亚红; 张力

    2011-01-01

    The paper introduces the design ideas and implementation of desktop-based virtual reality technology in courseware making. Combination of virtual reality technology with courseware teaching materials can reinforce independent learning of eourseware and knowledge interactivity, which leads to a significant improvement in learning efficiency and teaching quality.%介绍了桌面虚拟现实技术在课件制作中的设计思路及实现方法.指出将虚拟现实技术与课件教学内容的知识点相整合,可强化课件的学习自主性和知识交互性,从而提高学习效率和教学质量.

  4. API Global Sourcing Strategies 2010.

    Science.gov (United States)

    Bennett, Shannon

    2010-09-01

    The API Global Sourcing Strategies 2010 Conference, held in Berlin, included topics covering new developments in the field of global sourcing of active pharmaceutical ingredients (APIs). This conference report highlights selected presentations on development in Eastern API markets, specifically India and China, factors influencing changes in global API sourcing, and risk mitigation in API sourcing.

  5. Rısk analysis for pressure vessel with external corrosion using RBI method based on API 581

    Science.gov (United States)

    Naubnome, Viktor; Haryadi, Gunawan Dwi; Ismail, Rifky; Kim, Seon Jin

    2016-04-01

    Internal corrosion and external are the one major cause of accidents in liquid and natural gas in a pressure vessel. To lessen the vessel risk level, many companies have adopted and applied risk based inspection (RBI) methodology to risk reduction equipment, This study applied RBI methodology to optimize the inspection planing of the pressure vessel in power plant unit Jawa-Bali. In API 581, the risk situation for each type of equipment was classified into four levels: low risk level, medium-risk level, medium-high-risk level, and high level. This is expressed as a risk matrix. In this paper, semi-quantitative analysis method of risk-based inspection (RBI) was carried out for reducing the failure level of risk and optimized inspection plans, risk analysis of equipment failures resulting from corrosion need to be implemented. The result RBI analysis showed that pressure vessel has a medium high risk level and medium level. Failure mechanisms that occur in the pressure vessel is general thinning.

  6. Analysis and Applications API eBay

    OpenAIRE

    ŠIK, Martin

    2013-01-01

    The subject of this bachelor thesis "Analysis and Applications API eBay" is to create application based on the use of Application Programming Interface (API), released by eBay. The theoretical part is focused on explaining the fundamental issue of Internet auctions, e-commmerce, comparsion of auction portals and term "trust" as a key attribute of e-commerce. The practical part is based on analyse of principles and instruments of eBay API and create an application based on this interface. The ...

  7. Phylogenetic relationship of Turkish Apis mellifera subspecies based on sequencing of mitochondrial cytochrome C oxidase I region.

    Science.gov (United States)

    Özdil, F; İlhan, F

    2012-04-27

    Mitochondrial DNA sequence variation can be used to infer honey bee evolutionary relationships. We examined DNA sequence diversity in the cytochrome C oxidase I (COI or Cox1) gene segment of the mitochondrial genome in 112 samples of Apis mellifera from 15 different populations in Turkey. Six novel haplotypes were found for the COI gene segment. There were eight variable sites in the COI gene, although only three were parsimony-informative sites. The mean pairwise genetic distance was 0.3% for the COI gene segment. Neighbor-joining (NJ) trees of the COI gene segment were constructed with the published sequences of A. mellifera haplotypes that are available in GenBank; the genetic variation was compared among the different honeybee haplotypes. The NJ dendogram based on the COI sequences available in GenBank showed that Eastern European races were clustered together, whereas the Mellifera and Iberian haplotypes were clustered far apart. The haplotypes found in this study were clustered together with A. mellifera ligustica and some of the Greek honey bees (accession Nos. GU056169 and GU056170) found in NCBI GenBank database. This study expands the knowledge about the mitochondrial COI region and presents the first comprehensive sequence analysis of this region in Turkish honeybees.

  8. Comparing Web Applications with Desktop Applications: An Empirical Study

    DEFF Research Database (Denmark)

    Pop, Paul

    2002-01-01

    of developing and using such applications. In this paper we present a comparison of web and desktop applications from the usability point of view. The comparison is based on an empirical study that investigates the performance of a group of users on two calendaring applications: Yahoo!Calendar and Microsoft...... Calendar. The study shows that in the case of web applications the performance of the users is significantly reduced, mainly because of the restricted interaction mechanisms provided by current web browsers.......In recent years, many desktop applications have been ported to the world wide web in order to reduce (multiplatform) development, distribution and maintenance costs. However, there is little data concerning the usability of web applications, and the impact of their usability on the total cost...

  9. Open, Sharable, and Extensible Data Management for the Korea National Aquatic Ecological Monitoring and Assessment Program: A RESTful API-Based Approach

    Directory of Open Access Journals (Sweden)

    Meilan Jiang

    2016-05-01

    Full Text Available Implemented by a national law, the National Aquatic Ecological Monitoring Program (NAEMP has been assessing the ecological health status of surface waters, focusing on streams and rivers, in Korea since 2007. The program involves ecological monitoring of multiple aquatic biota such as benthic diatoms, macroinvertebrates, fish, and plants as well as water quality and habitat parameters. Taking advantage of the national scale of long-term aquatic ecological monitoring and the standardization of protocols and methods, the datasets in NAEMP provide many opportunities for various advanced comparative and synthetic studies, policy-making, and ecological management. In order to realize these potentials and opportunities, we have developed a RESTful API-based data management system called OSAEM (the Open, Sharable and Extensible Data Management System for Aquatic Ecological Monitoring, which is designed to be open, sharable, and extensible. In this paper, we introduce the RESTful API-based data management approach, present the RESTful API for the OSAEM system, and discuss its applicability. An OSAEM prototype system is currently available on a commercial cloud service (Amazon EC2 but the system remains under active development.

  10. Architectural Desktop : release 3.3

    DEFF Research Database (Denmark)

    Skauge, Jørn

    2002-01-01

    Øvelser i ADT's mest grundlæggende dele på basis af modellering af et lille og simpelt hus. Der arbejdes primært med værktøjerne i designdelens menu. 1. udgave med titel: Architectural Desktop (Fiskers hus). 2002. 60 sider.......Øvelser i ADT's mest grundlæggende dele på basis af modellering af et lille og simpelt hus. Der arbejdes primært med værktøjerne i designdelens menu. 1. udgave med titel: Architectural Desktop (Fiskers hus). 2002. 60 sider....

  11. An API-based search system for one click access to information

    NARCIS (Netherlands)

    Ionita, Dan; Tax, Niek; Hiemstra, Djoerd

    2013-01-01

    This paper proposes a prototype One Click access system, based on previous work in the field and the related 1CLICK-2@NTCIR10 task. The proposed solution integrates methods from into a three tier algorithm: query categorization, information extraction and output generation and offers suggestions on

  12. Google Ajax Search API

    CERN Document Server

    Fitzgerald, Michael

    2007-01-01

    Use the Google Ajax Search API to integrateweb search, image search, localsearch, and other types of search intoyour web site by embedding a simple, dynamicsearch box to display search resultsin your own web pages using a fewlines of JavaScript. For those who do not want to write code,the search wizards and solutions builtwith the Google Ajax Search API generatecode to accomplish common taskslike adding local search results to a GoogleMaps API mashup, adding videosearch thumbnails to your web site, oradding a news reel with the latest up todate stories to your blog. More advanced users can

  13. Aquatic Habitats: Exploring Desktop Ponds. Teacher's Guide.

    Science.gov (United States)

    Barrett, Katharine; Willard, Carolyn

    This book, for grades 2-6, is designed to provide students with a highly motivating and unique opportunity to investigate an aquatic habitat. Students set up, observe, study, and reflect upon their own "desktop ponds." Accessible plants and small animals used in these activities include Elodea, Tubifex worms, snails, mosquito larvae, and fish.…

  14. 基于 ARM 的桌面型3D打印机控制系统设计%Design of desktop 3D printer control system based on ARM

    Institute of Scientific and Technical Information of China (English)

    谭秀腾; 郭小定; 李小龙; 余亮

    2014-01-01

    针对基于单片机为控制器的桌面型3D打印机控制系统中存在的处理速度慢、片外芯片多、电路复杂、打印质量不高等问题,设计了基于ARM为控制器的桌面型3D打印机控制系统。系统采用了NXP公司推出的基于ARM Cortex-M3内核的LPC1768微控制器,用它进行与上位机通信、数据处理、模拟量采集与处理、信号控制,选用A4988专用两相步进电机驱动器实现步进电机细分驱动,简化步进电机细分驱动的设计,行程开关电路采用GK152红外光电传感器。软件采用了PID方式调节加热床、挤出机加热温度。文中论述了控制系统主要硬件电路设计和软件的实现流程,系统测试表明性能良好。%The desktop 3D printer control systems with a sigle-chip controller have problems of slow processing speed, more pieces of outside chips, circuit complexity and poor quality of printing.To solve these problems, a desktop 3D printer control system with an ARM controller is designed.The system employs the LPC1768 microcon-troller based on ARM Cortex-M3 core which is introduced by the NXP and used to communicate with the host com-puter, data processing, analog acquisition and processing, signal control, used A4988 special two-phase stepper motor driver to implement stepper motor subdivision drive and to simplify the drive design for stepping motor.The travel switch circuit adopts GK152 infrared photoelectric sensor.The software adopted PID method in order to adjust the heating temperature of heating bed and extruder.This paper discusses the main hardware circuit design and soft-ware realization process of the control system.The System testing shows good performance.

  15. Mars Rover Photos API

    Data.gov (United States)

    National Aeronautics and Space Administration — This API is designed to collect image data gathered by NASA's Curiosity, Opportunity, and Spirit rovers on Mars and make it more easily available to other...

  16. GIBS API for Developers

    Data.gov (United States)

    National Aeronautics and Space Administration — API using Global Imagery Browse Services (GIBS) designed to deliver global, full-resolution satellite imagery to users in a highly responsive manner, enabling...

  17. Design of Automatic LeveIing Device Based on MarIin Firmware Desktop 3D Printer%基于MarIin固件桌面级3D打印机自动调平装置设计

    Institute of Scientific and Technical Information of China (English)

    宗殿栋; 汪地; 李卫成; 姜海龙; 刘谋玉

    2016-01-01

    桌面级3D打印机第一层的打印质量对于打印的成败非常重要,自动调平装置可以保证打印第一层时的打印可靠性,同时可以降低桌面级3D打印机的使用难度。基于桌面级3D打印机使用广泛的开源MarIin固件,在主程序和运动控制方面进行分析,设计了一种新型桌面级3D打印机自动调平装置,与现有自动调平装置相比,具有结构简单、稳定性高,通用性好的优点。%This paper based on a wide range use of open source MarIin firmware,anaIysis this firmware in main program and motion controI.The design of a new type of desktop 3D printer automatic IeveIing device,compared with the existing au-tomatic IeveIing device,with the advantage of a simpIe structure, high stabiIity.

  18. Web API Recommendation Based on User Usage History and Reputation Evaluation%基于用户使用历史与信誉评价的Web API推荐

    Institute of Scientific and Technical Information of China (English)

    曹步清; 刘建勋; 唐明董; 谢芬方

    2015-01-01

    With the release of more and more Web API services on Internet,it becomes a challenging research problem that how to recommend Web APIs that developer user are interested in and reputation degrees are high,to construct high quality and trustworthy software service system. This paper presents Web API service recommendation approach based on user usage history and reputation evaluation ( WASR) . It computes the similarity between user history records and Web API services,and gets user interest degree. Service reputation degree is computed by considering the user score of Web API,the score contributions of those Mashup services calling the Web API, and traffic flow of Web API based on statistical data by Alexa. It ranks and recommends Web API services according to the user interest degree and service reputation degree of Web APIs. Experimental results show that this approach can recommend Web API services with higher DCG of user interest degree than those of SR-based approach,and higher DCG of service reputation degree than those of UI-based approach.%随着网络上发布的Web API服务越来越多,如何推荐给开发者用户感兴趣、信誉度高的Web API服务,以构建高质量高可信的软件服务系统,成为一个具有挑战性的研究问题。为此,提出一种基于用户使用历史与信誉评价的Web API服务推荐方法。计算用户使用历史记录与Web API之间的相似度,获得Web API的用户兴趣值。综合用户的Web API评分,调用Web API的Mashup服务的评价贡献和Alexa统计的Web API访问流量,获得Web API的信誉评价值。根据Web API的用户兴趣值以及信誉评价值,实现Web API的排名与推荐。实验结果表明,该方法推荐的Web API用户兴趣度DCG值高于SR-Based方法,服务信誉度DCG值高于UI-Based方法。

  19. IBM System i APIs at Work

    CERN Document Server

    Vining, Bruce; Hawkins, Ron

    2007-01-01

    This new edition of the bestselling i5 application programming interface (API) book includes powerful new APIs and updated code to give programmers a working knowledge of the APIs available under i5/OS. Using real business-world examples, this book explains APIs that serve webpages, list APIs, APIs that work with user spaces, dynamic index APIs, APIs that retrieve system values, job information and job queue information APIs, APIs that work with data queues, APIs for error handling and message handling, and spool file APIs, among many others. Completely revised and including eight new chapters

  20. Identification of Yersinia enterocolitica in minced meat: a comparative analysis of API 20E, Yersinia identification kit and a 16S rRNA-based PCR method.

    Science.gov (United States)

    Arnold, T; Neubauer, H; Nikolaou, K; Roesler, U; Hensel, A

    2004-02-01

    The isolation and identification of Yersinia enterocolitica from minced meat on CIN agar medium is still one of the major problems in food microbiology because of the low selectivity of cefsulodin-irgasan-novobiocin (CIN) agar. A total of 198 minced meat samples were collected from commercial establishments (butcher shops and supermarkets) in seven German cities in order to investigate the sensitivity and specificity of three identification techniques suitable for the differentiation of Y. enterocolitica within the rich background flora on CIN agar plates. As expected isolation of Y. enterocolitica from minced meat on CIN agar medium after 72 h enrichment in peptone, sorbitol and bile salts (PSB) broth was difficult because all plates were abundantly covered with numerous 'typical'Yersinia-like colonies of bull's eye appearance as well as with atypical colonies. Based on the phenotype of the colonies it was possible to detect colonies showing Yersinia-like growth on CIN agar in 52 samples (26%). For identification of Y. enterocolitica the API 20E system (bioMerieux, Nürtingen, Germany), the Yersinia identification kit (Merlin, Bornheim-Hersel, Germany) and a 16S rRNA based PCR assay were compared. Only in one sample (0.5%) a Y. enterocolitica strain was detected by all methods. Of the three identification systems tested for routine laboratory diagnostics the API 20E system was found to be the most suitable tool to identify Y. enterocolitica colonies within the rich background flora from minced meat samples on CIN agar plates.

  1. Microprocessors: from desktops to supercomputers.

    Science.gov (United States)

    Baskett, F; Hennessy, J L

    1993-08-13

    Continuing improvements in integrated circuit technology and computer architecture have driven microprocessors to performance levels that rival those of supercomputers-at a fraction of the price. The use of sophisticated memory hierarchies enables microprocessor-based machines to have very large memories built from commodity dynamic random access memory while retaining the high bandwidth and low access time needed in a high-performance machine. Parallel processors composed of these high-performance microprocessors are becoming the supercomputing technology of choice for scientific and engineering applications. The challenges for these new supercomputers have been in developing multiprocessor architectures that are easy to program and that deliver high performance without extraordinary programming efforts by users. Recent progress in multiprocessor architecture has led to ways to meet these challenges.

  2. Mars Atmospheric Aggregation System API

    Data.gov (United States)

    National Aeronautics and Space Administration — The {MAAS} API is an open source REST API built to help make it easier and more efficient to build interactive applications that want to utilize the wealth of...

  3. Data.gov CKAN API

    Data.gov (United States)

    General Services Administration — The data.gov catalog is powered by CKAN, a powerful open source data platform that includes a robust API. Please be aware that data.gov and the data.gov CKAN API...

  4. HydroDesktop as a Community Designed and Developed Resource for Hydrologic Data Discovery and Analysis

    Science.gov (United States)

    Ames, D. P.

    2013-12-01

    As has been seen in other informatics fields, well-documented and appropriately licensed open source software tools have the potential to significantly increase both opportunities and motivation for inter-institutional science and technology collaboration. The CUAHSI HIS (and related HydroShare) projects have aimed to foster such activities in hydrology resulting in the development of many useful community software components including the HydroDesktop software application. HydroDesktop is an open source, GIS-based, scriptable software application for discovering data on the CUAHSI Hydrologic Information System and related resources. It includes a well-defined plugin architecture and interface to allow 3rd party developers to create extensions and add new functionality without requiring recompiling of the full source code. HydroDesktop is built in the C# programming language and uses the open source DotSpatial GIS engine for spatial data management. Capabilities include data search, discovery, download, visualization, and export. An extension that integrates the R programming language with HydroDesktop provides scripting and data automation capabilities and an OpenMI plugin provides the ability to link models. Current revision and updates to HydroDesktop include migration of core business logic to cross platform, scriptable Python code modules that can be executed in any operating system or linked into other software front-end applications.

  5. Cloud Policy Model in the Desktop Management System

    Directory of Open Access Journals (Sweden)

    Fang Zhao

    2010-11-01

    Full Text Available By studying the policy and desktop management systems theories, referencing the Internet Engineering Task Force (IETF policy model and theories of cloud computing, this paper proposed a cloud policy model that can be applied in specific desktop management system. It mainly explains the whole system framework and its implementation mechanisms, and it discusses the problems and solutions that the cloud policy model uses in the desktop management system.

  6. Dynamic Resource Allocation in Desktop Grids

    Directory of Open Access Journals (Sweden)

    Bismi A S,

    2010-08-01

    Full Text Available Grid computing (or the use of computational grids is the application of several computers to a single problem at the same time. In grid computing ,the computing becomes pervasive and individual users(or client applicationgain access to computing resources (processors ,storage ,data,applications,and so onas needed with little or noknowledge of where those resources are located or what the underlying technologies, hardware ,operating system and so on. This paper address the problem of resource scheduling ,and there are so many resource scheduling algorithms .Resource scheduling algorithm may be centralized one and distributed one. One of the latest one is the multi-variable best fit algorithm, which deals with storage systems, and it enhanced in this work. and this algorithm is dealing withdata grids for blade servers. so, this algorithm is modified for computational grids, especially with desktop systems with minimum spanning algorithm for node selection and it is giving good results. In desktop grid environment, dynamic scheduling becomes very important and globus like toolkits are not having the scheduler as its own, and it needs other schedulers are not specially for computational grids.

  7. Evidence of Apis cerana Sacbrood virus Infection in Apis mellifera

    Science.gov (United States)

    Gong, Hong-Ri; Chen, Xiu-Xian; Chen, Yan Ping; Hu, Fu-Liang; Zhang, Jiang-Lin; Lin, Zhe-Guang; Yu, Ji-Wei

    2016-01-01

    Sacbrood virus (SBV) is one of the most destructive viruses in the Asian honeybee Apis cerana but is much less destructive in Apis mellifera. In previous studies, SBV isolates infecting A. cerana (AcSBV) and SBV isolates infecting A. mellifera (AmSBV) were identified as different serotypes, suggesting a species barrier in SBV infection. In order to investigate this species isolation, we examined the presence of SBV infection in 318 A. mellifera colonies and 64 A. cerana colonies, and we identified the genotypes of SBV isolates. We also performed artificial infection experiments under both laboratory and field conditions. The results showed that 38 A. mellifera colonies and 37 A. cerana colonies were positive for SBV infection. Phylogenetic analysis based on RNA-dependent RNA polymerase (RdRp) gene sequences indicated that A. cerana isolates and most A. mellifera isolates formed two distinct clades but two strains isolated from A. mellifera were clustered with the A. cerana isolates. In the artificial-infection experiments, AcSBV negative-strand RNA could be detected in both adult bees and larvae of A. mellifera, although there were no obvious signs of the disease, demonstrating the replication of AcSBV in A. mellifera. Our results suggest that AcSBV is able to infect A. mellifera colonies with low prevalence (0.63% in this study) and pathogenicity. This work will help explain the different susceptibilities of A. cerana and A. mellifera to sacbrood disease and is potentially useful for guiding beekeeping practices. PMID:26801569

  8. Writing Essays on a Laptop or a Desktop Computer: Does It Matter?

    Science.gov (United States)

    Ling, Guangming; Bridgeman, Brent

    2013-01-01

    To explore the potential effect of computer type on the Test of English as a Foreign Language-Internet-Based Test (TOEFL iBT) Writing Test, a sample of 444 international students was used. The students were randomly assigned to either a laptop or a desktop computer to write two TOEFL iBT practice essays in a simulated testing environment, followed…

  9. Direct-write scanning probe lithography: towards a desktop fab

    Science.gov (United States)

    Giam, Louise R.; Senesi, Andrew J.; Liao, Xing; Wong, Lu Shin; Chai, Jinan; Eichelsdoerfer, Daniel J.; Shim, Wooyoung; Rasin, Boris; He, Shu; Mirkin, Chad A.

    2011-06-01

    Massively parallel scanning-probe based methods have been used to address the challenges of nanometer to millimeter scale printing for a variety of materials and mark a step towards the realization of a "desktop fab." Such tools enable simple, flexible, high-throughput, and low-cost nano- and microscale patterning, which allow researchers to rapidly synthesize and study systems ranging from nanoparticle synthesis to biological processes. We have developed a novel scanning probe-based cantilever-free printing method termed polymer pen lithography (PPL), which uses an array of elastomeric tips to transfer materials (e.g. alkanethiols, proteins, polymers) in a direct-write manner onto a variety of surfaces. This technique takes the best attributes of dip-pen nanolithography (DPN) and eliminates many of the disadvantages of contact printing. Various related techniques such as beam pen lithography (BPL), scanning probe block copolymer lithography (SPBCL), and hard-tip, soft spring lithography (HSL) are also discussed.

  10. Citrix XenApp 7.5 desktop virtualization solutions

    CERN Document Server

    Paul, Andy

    2014-01-01

    If you are a Citrix® engineer, a virtualization consultant, or an IT project manager with prior experience of using Citrix XenApp® and related technologies for desktop virtualization and want to further explore the power of XenApp® for flawless desktop virtualization, then this book is for you.

  11. 36 CFR 1194.26 - Desktop and portable computers.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Desktop and portable computers. 1194.26 Section 1194.26 Parks, Forests, and Public Property ARCHITECTURAL AND TRANSPORTATION... § 1194.26 Desktop and portable computers. (a) All mechanically operated controls and keys shall...

  12. Exploring Graphic Design. A Short Course in Desktop Publishing.

    Science.gov (United States)

    Stanley, MLG

    This course in desktop publishing contains seven illustrated modules designed to meet the following objectives: (1) use a desktop publishing program to explore advanced topics in graphic design; (2) learn about typography and how to make design decisions on the use of typestyles; (3) learn basic principles in graphic communications and apply them…

  13. Research on Development of WebGIS Based on AJAXand Google Maps API%基于AJAX和Google Maps API的WebGIS开发研究

    Institute of Scientific and Technical Information of China (English)

    唐桂文; 谭衍涛

    2013-01-01

    通过介绍AJAX技术的相关原理、Google Maps地图服务及其应用程序接口Google Maps API,提出了基于AJAX及Google Maps平台的WebGIS开发新技术.通过构建发布气象信息的WebGIS实例,探索在Google Maps 平台上利用AJAX通过XMLHttpRequest对象异步调用XML数据实现动态加载地理信息和气象信息的关键步骤.研究结果表明,WebGIS实现的新模式,能够较好地解决传统WebGIS的固有缺点,如加快了响应速度、增强了用户体验和方便了服务扩充等.%In this paper,a new technology of WebGIS development based on AJAX and Google Maps is proposed,through introducing the relevant principles of AJAX technology and Google Maps mapping service and its application programming interface that is named Google Maps API.By constructing an example of WebGIS website used for releasing the meteorological information,it explores the key steps of dynamically loading geographic information and weather information that relies on AJAX technology which can use the XMLHttpRequest object to call XML data asynchronously between the Google Maps platform and client browsers.The research results show that the new WebGIS implementation model can solve the inherent shortcomings of traditional WebGIS and present many advantages,such as accelerating the speed of response,enhancing the user experience and facilitating the service expansion etc.

  14. Turbulence Visualization at the Terascale on Desktop PCs

    KAUST Repository

    Treib, M.

    2012-12-01

    Despite the ongoing efforts in turbulence research, the universal properties of the turbulence small-scale structure and the relationships between small-and large-scale turbulent motions are not yet fully understood. The visually guided exploration of turbulence features, including the interactive selection and simultaneous visualization of multiple features, can further progress our understanding of turbulence. Accomplishing this task for flow fields in which the full turbulence spectrum is well resolved is challenging on desktop computers. This is due to the extreme resolution of such fields, requiring memory and bandwidth capacities going beyond what is currently available. To overcome these limitations, we present a GPU system for feature-based turbulence visualization that works on a compressed flow field representation. We use a wavelet-based compression scheme including run-length and entropy encoding, which can be decoded on the GPU and embedded into brick-based volume ray-casting. This enables a drastic reduction of the data to be streamed from disk to GPU memory. Our system derives turbulence properties directly from the velocity gradient tensor, and it either renders these properties in turn or generates and renders scalar feature volumes. The quality and efficiency of the system is demonstrated in the visualization of two unsteady turbulence simulations, each comprising a spatio-temporal resolution of 10244. On a desktop computer, the system can visualize each time step in 5 seconds, and it achieves about three times this rate for the visualization of a scalar feature volume. © 1995-2012 IEEE.

  15. Parallelized Vlasov-Fokker-Planck solver for desktop personal computers

    Science.gov (United States)

    Schönfeldt, Patrik; Brosi, Miriam; Schwarz, Markus; Steinmann, Johannes L.; Müller, Anke-Susanne

    2017-03-01

    The numerical solution of the Vlasov-Fokker-Planck equation is a well established method to simulate the dynamics, including the self-interaction with its own wake field, of an electron bunch in a storage ring. In this paper we present Inovesa, a modularly extensible program that uses opencl to massively parallelize the computation. It allows a standard desktop PC to work with appropriate accuracy and yield reliable results within minutes. We provide numerical stability-studies over a wide parameter range and compare our numerical findings to known results. Simulation results for the case of coherent synchrotron radiation will be compared to measurements that probe the effects of the microbunching instability occurring in the short bunch operation at ANKA. It will be shown that the impedance model based on the shielding effect of two parallel plates can not only describe the instability threshold, but also the presence of multiple regimes that show differences in the emission of coherent synchrotron radiation.

  16. Implement Method of Desktop Environment Supporting Multitask Based on Embedded System%一种支持多任务桌面环境的嵌入式系统解决方案

    Institute of Scientific and Technical Information of China (English)

    杨志义; 回永利; 李士宁; 李志刚

    2011-01-01

    无论是在个人消费电子,还是在车载娱乐系统中,对支持多任务的嵌入式桌面环境的需求越来越迫切.友好的多任务支持为用户提供易用、方便的操作体验.一个健壮的嵌入式生态系统不仅要为用户的日常应用提供基本的桌面功能和应用,还要为开发者提供为该系统编写应用所需的工具和文档.通过守护线程和知名管道机制实现支持多任务的嵌入式桌面系统,并介绍了交互平台开发包的搭建.%No matter personal consumer electronic products,or automobiles entertainment systems, they all cry for the desktop environment supporting multitask. User-friendly multitask support brings easy and convenient experience. A strong embedded ecosystem should provide basic desktop functions and applications for daily needs as well as tools and documentation for developers to write stand-alone applications for the system. With Daemon thread and well-known Pipe mechanism,a desktop environment supporting multitasks was implemented,and the paper introduced a method to develop the SDK for programmers.

  17. Integrated platform and API for electrophysiological data.

    Science.gov (United States)

    Sobolev, Andrey; Stoewer, Adrian; Leonhardt, Aljoscha; Rautenberg, Philipp L; Kellner, Christian J; Garbers, Christian; Wachtler, Thomas

    2014-01-01

    Recent advancements in technology and methodology have led to growing amounts of increasingly complex neuroscience data recorded from various species, modalities, and levels of study. The rapid data growth has made efficient data access and flexible, machine-readable data annotation a crucial requisite for neuroscientists. Clear and consistent annotation and organization of data is not only an important ingredient for reproducibility of results and re-use of data, but also essential for collaborative research and data sharing. In particular, efficient data management and interoperability requires a unified approach that integrates data and metadata and provides a common way of accessing this information. In this paper we describe GNData, a data management platform for neurophysiological data. GNData provides a storage system based on a data representation that is suitable to organize data and metadata from any electrophysiological experiment, with a functionality exposed via a common application programming interface (API). Data representation and API structure are compatible with existing approaches for data and metadata representation in neurophysiology. The API implementation is based on the Representational State Transfer (REST) pattern, which enables data access integration in software applications and facilitates the development of tools that communicate with the service. Client libraries that interact with the API provide direct data access from computing environments like Matlab or Python, enabling integration of data management into the scientist's experimental or analysis routines.

  18. Web API Fragility: How Robust is Your Web API Client

    NARCIS (Netherlands)

    Espinha, T.; Zaidman, A.; Gross, H.G.

    2014-01-01

    Web APIs provide a systematic and extensible approach for application-to-application interaction. A large number of mobile applications makes use of web APIs to integrate services into apps. Each Web API’s evolution pace is determined by their respective developer and mobile application developers a

  19. Empirical Analysis of Server Consolidation and Desktop Virtualization in Cloud Computing

    Directory of Open Access Journals (Sweden)

    Bao Rong Chang

    2013-01-01

    Full Text Available Physical server transited to virtual server infrastructure (VSI and desktop device to virtual desktop infrastructure (VDI have the crucial problems of server consolidation, virtualization performance, virtual machine density, total cost of ownership (TCO, and return on investments (ROI. Besides, how to appropriately choose hypervisor for the desired server/desktop virtualization is really challenging, because a trade-off between virtualization performance and cost is a hard decision to make in the cloud. This paper introduces five hypervisors to establish the virtual environment and then gives a careful assessment based on C/P ratio that is derived from composite index, consolidation ratio, virtual machine density, TCO, and ROI. As a result, even though ESX server obtains the highest ROI and lowest TCO in server virtualization and Hyper-V R2 gains the best performance of virtual machine management; both of them however cost too much. Instead the best choice is Proxmox Virtual Environment (Proxmox VE because it not only saves the initial investment a lot to own a virtual server/desktop infrastructure, but also obtains the lowest C/P ratio.

  20. Visual attention for a desktop virtual environment with ambient scent.

    Science.gov (United States)

    Toet, Alexander; van Schaik, Martin G

    2013-01-01

    In the current study participants explored a desktop virtual environment (VE) representing a suburban neighborhood with signs of public disorder (neglect, vandalism, and crime), while being exposed to either room air (control group), or subliminal levels of tar (unpleasant; typically associated with burned or waste material) or freshly cut grass (pleasant; typically associated with natural or fresh material) ambient odor. They reported all signs of disorder they noticed during their walk together with their associated emotional response. Based on recent evidence that odors reflexively direct visual attention to (either semantically or affectively) congruent visual objects, we hypothesized that participants would notice more signs of disorder in the presence of ambient tar odor (since this odor may bias attention to unpleasant and negative features), and less signs of disorder in the presence of ambient grass odor (since this odor may bias visual attention toward the vegetation in the environment and away from the signs of disorder). Contrary to our expectations the results provide no indication that the presence of an ambient odor affected the participants' visual attention for signs of disorder or their emotional response. However, the paradigm used in present study does not allow us to draw any conclusions in this respect. We conclude that a closer affective, semantic, or spatiotemporal link between the contents of a desktop VE and ambient scents may be required to effectively establish diagnostic associations that guide a user's attention. In the absence of these direct links, ambient scent may be more diagnostic for the physical environment of the observer as a whole than for the particular items in that environment (or, in this case, items represented in the VE).

  1. Learning Bing maps API

    CERN Document Server

    Sinani, Artan

    2013-01-01

    This is a practical, hands-on guide with illustrative examples, which will help you explore the vast universe of Bing maps.If you are a developer who wants to learn how to exploit the numerous features of Bing Maps then this book is ideal for you. It can also be useful for more experienced developers who wish to explore other areas of the APIs. It is assumed that you have some knowledge of JavaScript, HTML, and CSS. For some chapters a working knowledge of .Net and Visual Studio is also needed.

  2. AUTOMATED API TESTING APPROACH

    Directory of Open Access Journals (Sweden)

    SUNIL L. BANGARE

    2012-02-01

    Full Text Available Software testing is an investigation conducted to provide stakeholders with information about the quality of the product or service under test. With the help of software testing we can verify or validate the software product. Normally testing will be done after development of software but we can perform the software testing at the time of development process also. This paper will give you a brief introduction about Automated API Testing Tool. This tool of testing will reduce lots of headache after the whole development of software. It saves time as well as money. Such type of testing is helpful in the Industries & Colleges also.

  3. 基于桌面虚拟技术的影视剪辑课程改革%The Course Reform of Film Editing Based on Desktop Virtual Technology

    Institute of Scientific and Technical Information of China (English)

    朱姝

    2014-01-01

    T he broadening of the digital technology area proposes the new requirements for the teaching of the film and television majors in institutions of higher learning .Desktop virtual reality technology can provide a convenient operational platform for the film and television professional teaching in institutions of higher learning .Desktop vir-tual reality technology is only used properly ,and the functions and modules adapted to the teaching environments are constantly developed .The independent application-oriented talents can be cultivated for the film and television industry .%数字技术应用领域的拓宽对高等院校的影视专业课程教学提出了新的要求。桌面虚拟现实技术可为我国高等院校的影视专业的教学提供便捷的操作平台,要在课程教学中合理使用,并不断开发出适应教学环境的功能和模块,才能为影视行业培养出具有独立创作精神的应用型人才。

  4. 基于桌面虚拟技术的影视剪辑课程改革%The Course Reform of Film Editing Based on Desktop Virtual Technology

    Institute of Scientific and Technical Information of China (English)

    朱姝

    2014-01-01

    数字技术应用领域的拓宽对高等院校的影视专业课程教学提出了新的要求。桌面虚拟现实技术可为我国高等院校的影视专业的教学提供便捷的操作平台,要在课程教学中合理使用,并不断开发出适应教学环境的功能和模块,才能为影视行业培养出具有独立创作精神的应用型人才。%T he broadening of the digital technology area proposes the new requirements for the teaching of the film and television majors in institutions of higher learning .Desktop virtual reality technology can provide a convenient operational platform for the film and television professional teaching in institutions of higher learning .Desktop vir-tual reality technology is only used properly ,and the functions and modules adapted to the teaching environments are constantly developed .T he independent application -oriented talents can be cultivated for the film and television industry .

  5. LCCP Desktop Application v1.0 Engineering Reference

    Energy Technology Data Exchange (ETDEWEB)

    Beshr, Mohamed [University of Maryland, College Park; Aute, Vikrant [University of Maryland, College Park

    2014-04-01

    This Life Cycle Climate Performance (LCCP) Desktop Application Engineering Reference is divided into three parts. The first part of the guide, consisting of the LCCP objective, literature review, and mathematical background, is presented in Sections 2-4. The second part of the guide (given in Sections 5-10) provides a description of the input data required by the LCCP desktop application, including each of the input pages (Application Information, Load Information, and Simulation Information) and details for interfacing the LCCP Desktop Application with the VapCyc and EnergyPlus simulation programs. The third part of the guide (given in Section 11) describes the various interfaces of the LCCP code.

  6. Evidence of Apis cerana Sacbrood virus Infection in Apis mellifera.

    Science.gov (United States)

    Gong, Hong-Ri; Chen, Xiu-Xian; Chen, Yan Ping; Hu, Fu-Liang; Zhang, Jiang-Lin; Lin, Zhe-Guang; Yu, Ji-Wei; Zheng, Huo-Qing

    2016-04-01

    Sacbrood virus(SBV) is one of the most destructive viruses in the Asian honeybee Apis cerana but is much less destructive in Apis mellifera In previous studies, SBV isolates infecting A. cerana(AcSBV) and SBV isolates infecting A. mellifera(AmSBV) were identified as different serotypes, suggesting a species barrier in SBV infection. In order to investigate this species isolation, we examined the presence of SBV infection in 318A. mellifera colonies and 64A. cerana colonies, and we identified the genotypes of SBV isolates. We also performed artificial infection experiments under both laboratory and field conditions. The results showed that 38A. mellifera colonies and 37A. cerana colonies were positive for SBV infection. Phylogenetic analysis based on RNA-dependent RNA polymerase (RdRp) gene sequences indicated that A. cerana isolates and most A. mellifera isolates formed two distinct clades but two strains isolated fromA. mellifera were clustered with theA. cerana isolates. In the artificial-infection experiments, AcSBV negative-strand RNA could be detected in both adult bees and larvae ofA. mellifera, although there were no obvious signs of the disease, demonstrating the replication of AcSBV inA. mellifera Our results suggest that AcSBV is able to infectA. melliferacolonies with low prevalence (0.63% in this study) and pathogenicity. This work will help explain the different susceptibilities ofA. cerana and A. melliferato sacbrood disease and is potentially useful for guiding beekeeping practices.

  7. OFF, Open source Finite volume Fluid dynamics code: A free, high-order solver based on parallel, modular, object-oriented Fortran API

    Science.gov (United States)

    Zaghi, S.

    2014-07-01

    OFF, an open source (free software) code for performing fluid dynamics simulations, is presented. The aim of OFF is to solve, numerically, the unsteady (and steady) compressible Navier-Stokes equations of fluid dynamics by means of finite volume techniques: the research background is mainly focused on high-order (WENO) schemes for multi-fluids, multi-phase flows over complex geometries. To this purpose a highly modular, object-oriented application program interface (API) has been developed. In particular, the concepts of data encapsulation and inheritance available within Fortran language (from standard 2003) have been stressed in order to represent each fluid dynamics "entity" (e.g. the conservative variables of a finite volume, its geometry, etc…) by a single object so that a large variety of computational libraries can be easily (and efficiently) developed upon these objects. The main features of OFF can be summarized as follows: Programming LanguageOFF is written in standard (compliant) Fortran 2003; its design is highly modular in order to enhance simplicity of use and maintenance without compromising the efficiency; Parallel Frameworks Supported the development of OFF has been also targeted to maximize the computational efficiency: the code is designed to run on shared-memory multi-cores workstations and distributed-memory clusters of shared-memory nodes (supercomputers); the code's parallelization is based on Open Multiprocessing (OpenMP) and Message Passing Interface (MPI) paradigms; Usability, Maintenance and Enhancement in order to improve the usability, maintenance and enhancement of the code also the documentation has been carefully taken into account; the documentation is built upon comprehensive comments placed directly into the source files (no external documentation files needed): these comments are parsed by means of doxygen free software producing high quality html and latex documentation pages; the distributed versioning system referred as git

  8. ON XML AND Automation APIs-BASED CAD MODEL INTEGRATION AND EXCHANGE%基于XML和Automation APIs的CAD模型集成与交换研究

    Institute of Scientific and Technical Information of China (English)

    陈曼华

    2011-01-01

    异构数据源(例如不同CAD系统之间)的交换和共享是虚拟产品开发中信息集成的核心.一般是采用基于设计历史参数化建模方法进行模型交换,但特征和几何信息的交换导致了转换器规模变大;另外转换器采用过程模型作为中性文件,需要几何建模内核生成内部显式模型.为了解决该问题,提出了一种称之为MidCAD的共享集成平台,该平台将转换器和中性文件分开,这样商业CAD系统的转换器只和MidCAD进行交互.采用Microsoft开发的Automation APIs实现MidCAD的交互通信.转换器利用MidCAD的Automation APIs将源CAD模型转换为XML宏文件,或将XML宏文件转换为目标CAD系统的模型.对MidCAD集成平台进行了验证.%The exchange and sharing among heterogeneous data sources ( such as aroong different CAD systems) are the core of information integration in virtual product development.Generally, the design history-based parametric modelling approach is often adopted to exchange models, however, the size of each translator tends to be large caused by the exchanges of the feature and geometric information; meanwhile,it is necessary to generate an internal explicit model for geometric modelling kernel when the translators use procedural model as neutral file.To overcome the above-mentioned problems, this study presents a so-called MidCAD sharing integration platform.The proposed platform separates the translator from the neutral file so that the translators of different commercial CAD systems interact only with the MidCAD.This study adopts Automation APIs developed by Microsoft to implement interactive communication between MidCAD and commercial CAD systems.By using Automation APIs of MidCAD, the translator converts source CAD model into XML macro file, or converts XML macro file into target CAD system model.The MidCAD integration platform has been verified by a simple example.

  9. Twitter manager GO API intended for GNU Social API

    OpenAIRE

    Janiga, Jaroslav

    2015-01-01

    The bachelor’s thesis had two goals. The first one was to create API for GO programming language that communicates with GNU Social API. The second one was to create an application that uses the mentioned API. The main purpose of creating the application was to reduce the time spent with the login and logout of the accounts by the members in the white team. The application is intended for training purposes in JYVSECTEC project at JAMK University of Applied Sciences. JYVSECTEC sta...

  10. Mendeley Desktop-based Construction and Application of Bibliographic References Library%基于Mendeley Desktop的参考文献图书馆构建与应用

    Institute of Scientific and Technical Information of China (English)

    孙建虎; 储召军; 卢昊; 黄俊伟

    2013-01-01

    介绍免费参考文献管理软件Mendeley Desktop,以其1.5.1版为例,阐述如何利用它建立参考文献图书馆并对参考文献进行管理、阅读和引用.Mendeley Desktop可提供多种文献添加方式,PDF文档元数据自动提取功能最具特色;可提供多种图书馆和参考文献管理工具,方便文献阅读和管理;具有多种字处理软件插件,极大方便参考文献引用和写作.

  11. Microsoft Virtualization Master Microsoft Server, Desktop, Application, and Presentation Virtualization

    CERN Document Server

    Olzak, Thomas; Boomer, Jason; Keefer, Robert M

    2010-01-01

    Microsoft Virtualization helps you understand and implement the latest virtualization strategies available with Microsoft products. This book focuses on: Server Virtualization, Desktop Virtualization, Application Virtualization, and Presentation Virtualization. Whether you are managing Hyper-V, implementing desktop virtualization, or even migrating virtual machines, this book is packed with coverage on all aspects of these processes. Written by a talented team of Microsoft MVPs, Microsoft Virtualization is the leading resource for a full installation, migration, or integration of virtual syste

  12. Digital patient records and the medical desktop: an integrated physician workstation for medical informatics training.

    OpenAIRE

    Litt, H. I.; Loonsk, J. W.

    1992-01-01

    The Institute of Medicine and others have advocated a shift from a paper-based to an electronic medical record and many authorities have advanced the concept of a physician workstation that can provide access to a wide variety of both clinically and reference oriented medical information. We have developed a working model of an integrated physician workstation based on a graphically oriented "Medical Desktop," for personal computers. This system gives the user access to much of the informatio...

  13. A Review on Genomics APIs

    Directory of Open Access Journals (Sweden)

    Rajeswari Swaminathan

    2016-01-01

    Full Text Available The constant improvement and falling prices of whole human genome Next Generation Sequencing (NGS has resulted in rapid adoption of genomic information at both clinics and research institutions. Considered together, the complexity of genomics data, due to its large volume and diversity along with the need for genomic data sharing, has resulted in the creation of Application Programming Interface (API for secure, modular, interoperable access to genomic data from different applications, platforms, and even organizations. The Genomics APIs are a set of special protocols that assist software developers in dealing with multiple genomic data sources for building seamless, interoperable applications leading to the advancement of both genomic and clinical research. These APIs help define a standard for retrieval of genomic data from multiple sources as well as to better package genomic information for integration with Electronic Health Records. This review covers three currently available Genomics APIs: a Google Genomics, b SMART Genomics, and c 23andMe. The functionalities, reference implementations (if available and authentication protocols of each API are reviewed. A comparative analysis of the different features across the three APIs is provided in the Discussion section. Though Genomics APIs are still under active development and have yet to reach widespread adoption, they hold the promise to make building of complicated genomics applications easier with downstream constructive effects on healthcare.

  14. Intro to the Zotero API

    Directory of Open Access Journals (Sweden)

    Amanda Morton

    2013-04-01

    Full Text Available In this lesson, you’ll learn how to use python with the Zotero API to interact with your Zotero library. The Zotero API is a powerful interface that would allow you to build a complete Zotero client from scratch if you so desired. But like most APIs, it works in small, discrete steps, so we have to build our way up to the complicated requests we might want to use to access our Zotero libraries. But this incremental building gives us plenty of time to learn as we go along.

  15. Design and Implementation Tourism Information Database Based on Google Maps API%基于Google Maps API的旅游特色数据库的设计与实现

    Institute of Scientific and Technical Information of China (English)

    王振华; 吴海涛

    2011-01-01

    Google Maps AP1 which has an open, low cost and ease of use features, it can be applied to meteorology, geography, and tourism and other fields.Tourism features database is to achieve a new kind of Web-based GIS travel services, This paper is an example to create a Tourism features database, discusses the Google Maps API application in tourism.%Google Maps API[1]所具有的开放式、低成本和易用性等特点,使其能够应用到气象、地理,以及旅游等各个领域.旅游特色数据库是基于Web实现的一种新型GIS旅游服务,本文正是以建立旅游特色数据库为例,探讨了Google Maps API在旅游方面的应用.

  16. The Methodological Research of Automatic Web API Testing Based on Python%基于Python的Web API自动化测试方法研究

    Institute of Scientific and Technical Information of China (English)

    王大伟

    2015-01-01

    In the mobile app product development process to use a large number of Web API. Using the HTTP protocol to build for various client-side services, and manual testing by client-side for Web API needs huge workloads and limited input range. In order to improve the efficiency of the test execution, and save the cost of regression testing in manually, has designed and implemented an automated test platform, first introduces Web API testing and automation, and then provides several commonly used Web API test tools, following discusses in details the Web API design and implementation of the automated testing framework as well as the practical application.%在手机app产品开发过程中要大量采用Web API.利用HTTP协议,构建面向各种客户端的服务,而通过客户端对Web API进行手工测试,其工作量巨大而且输入的范围有限.为提高测试执行效率、节省人工回归成本,设计并实现了一款自动化测试平台,首先介绍了We b API测试及自动化,接着介绍了几款常用的Web API测试工具,然后详细论述了Web API自动化测试框架的设计和实现,以及实际运用.

  17. Mining Effective Temporal Specifications from Heterogeneous API Data

    Institute of Scientific and Technical Information of China (English)

    Qian Wu; Guang-Tai Liang; Qian-Xiang Wang; Hong Mei

    2011-01-01

    Temporal specifications for Application Programming Interfaces (APIs) serve as an important basis for many defect detection tools.As these specifications are often not well documented,various approaches have been proposed to automatically mine specifications typically from API library source code or from API client programs.However,the library-based approaches take substantial computational resources and produce rather limited useful specifications,while the client-based approaches suffer from high false positive rates.To address the issues of existing approaches,we propose a novel specification miniug approach,called MineHEAD,which exploits heterogeneous API data,including information from API client programs as well as API library source code and comments,to produce effective specifications for defect detection with low cost.In particular,MineHEAD first applies client-based specification mining to produce a collection of candidate specifications,and then exploits the related library source code and comments to identify and refine the real specifications from the candidates.Our evaluation results on nine open source projects show that MineHEAD produces effective specifications with average precision of 97.2%.

  18. Practical Implementation of 10 Rules for Writing REST APIs

    Directory of Open Access Journals (Sweden)

    Jiri Hradil

    2017-01-01

    Full Text Available This paper shows a practical implementation of “10 Rules for Writing REST APIs introduced in the article” (Hradil, 2016. The application is done in Invoice Home (Wikilane, 2016, an invoicing web application for small business and entrepreneurs available world-wide. The API is implemented in JSON hypermedia format (ECMA International, 2016 and with Ruby on Rails framework (Hansson, 2016. The main purpose of the API is to allow connection of Invoice Home with external systems and offer Invoice Home data in simpler format compared to the current HTML format of the full-stack web application. The paper could be also used as a basic template or pattern for any other implementation of the JSON API in any web-based application.

  19. Ablation Modeling of Ares-I Upper State Thermal Protection System Using Thermal Desktop

    Science.gov (United States)

    Sharp, John R.; Page, Arthur T.

    2007-01-01

    The thermal protection system (TPS) for the Ares-I Upper Stage will be based on Space Transportation System External Tank (ET) and Solid Rocket Booster (SRB) heritage materials. These TPS materials were qualified via hot gas testing that simulated ascent and re-entry aerothermodynamic convective heating environments. From this data, the recession rates due to ablation were characterized and used in thermal modeling for sizing the thickness required to maintain structural substrate temperatures. At Marshall Space Flight Center (MSFC), the in-house code ABL is currently used to predict TPS ablation and substrate temperatures as a FORTRAN application integrated within SINDA/G. This paper describes a comparison of the new ablation utility in Thermal Desktop and SINDA/FLUINT with the heritage ABL code and empirical test data which serves as the validation of the Thermal Desktop software for use on the design of the Ares-I Upper Stage project.

  20. Unique honey bee (Apis mellifera hive component-based communities as detected by a hybrid of phospholipid fatty-acid and fatty-acid methyl ester analyses.

    Directory of Open Access Journals (Sweden)

    Kirk J Grubbs

    Full Text Available Microbial communities (microbiomes are associated with almost all metazoans, including the honey bee Apis mellifera. Honey bees are social insects, maintaining complex hive systems composed of a variety of integral components including bees, comb, propolis, honey, and stored pollen. Given that the different components within hives can be physically separated and are nutritionally variable, we hypothesize that unique microbial communities may occur within the different microenvironments of honey bee colonies. To explore this hypothesis and to provide further insights into the microbiome of honey bees, we use a hybrid of fatty acid methyl ester (FAME and phospholipid-derived fatty acid (PLFA analysis to produce broad, lipid-based microbial community profiles of stored pollen, adults, pupae, honey, empty comb, and propolis for 11 honey bee hives. Averaging component lipid profiles by hive, we show that, in decreasing order, lipid markers representing fungi, Gram-negative bacteria, and Gram-positive bacteria have the highest relative abundances within honey bee colonies. Our lipid profiles reveal the presence of viable microbial communities in each of the six hive components sampled, with overall microbial community richness varying from lowest to highest in honey, comb, pupae, pollen, adults and propolis, respectively. Finally, microbial community lipid profiles were more similar when compared by component than by hive, location, or sampling year. Specifically, we found that individual hive components typically exhibited several dominant lipids and that these dominant lipids differ between components. Principal component and two-way clustering analyses both support significant grouping of lipids by hive component. Our findings indicate that in addition to the microbial communities present in individual workers, honey bee hives have resident microbial communities associated with different colony components.

  1. A Parallelized Vlasov-Fokker-Planck-Solver for Desktop PCs

    CERN Document Server

    Schönfeldt,; Brosi,; Miriam,; Schwarz,; Markus,; Steinmann,; L., Johannes; Müller,; Anke-Susanne,

    2016-01-01

    The numerical solution of the Vlasov-Fokker-Planck equation is a well established method to simulate the dynamics, including the self-interaction with its own wake field, of an electron bunch in a storage ring. In this paper we present Inovesa, a modularly extensible program that uses OpenCL to massively parallelize the computation. It allows a standard desktop PC to work with appropriate accuracy and yield reliable results within minutes. We provide numerical stability-studies over a wide parameter range and compare our numerical findings to known results. Simulation results for the case of coherent synchrotron radiation will be compared to measurements that probe the effects of the micro-bunching instability occurring in the short bunch operation at ANKA. It will be shown that the impedance model based on the shielding effect of two parallel plates can not only describe the instability threshold, but also the presence of multiple regimes that show differences in the emission of coherent synchrotron radiatio...

  2. Innovative desktop learning tools. Implications for rural hospitals and physicians.

    Science.gov (United States)

    Oeffinger, J C; Hiebeler, L; Sherman, T; Gaskill, M; Portante, T; Polasek, J; Litterer, K

    1992-12-17

    Innovative methods of providing workplace education for health care professionals may be a key to the survival of rural hospitals in America. Such methods must overcome time, distance, cost and organizational constraints, and take into account the structure of the learning experience. The Texas Hospital Education and Research Foundation has recently been involved in two programs that tested new approaches to worker education using distance-learning strategies. The projects--resource sharing among rural directors of nursing and training for cancer tumor registrars--used computer-conferencing technology. A new model using existing satellite, audio-conferencing, and computer-based instruction augmented by computer conferencing is proposed. The Computer-Related Assisted Distance Learning Enhancement (CRADLE) model integrates existing technologies to provide education to health care workers at their desktop. The Cancer Learning Center (CLC) tested peer collaboration, the primary component of the model. The ultimate goal is to have the system available to all tumor registrars in Texas, and to secure funding to implement rural nursing and rural high-school health occupations education projects. Current projects from set-up through results are presented.

  3. A Checkpoint Storage System for Desktop Grid Computing

    CERN Document Server

    Kiswany, Samer Al; Vazhkudai, Sudharshan S

    2007-01-01

    Checkpointing is an indispensable technique to provide fault tolerance for long-running high-throughput applications like those running on desktop grids. In these environments, a checkpoint storage system can offer multiple benefits: reduce the load on a traditional file system, offer high-performance through specialization, and, finally, optimize checkpoint data management by taking into account application semantics. Such a storage system can present a unifying abstraction to checkpoint operations, while hiding the fact that there are no dedicated resources to store the checkpoint data. This paper presents a dedicated checkpoint storage system for desktop grid environments. Our solution uses scavenged disk space from participating desktops to build an inexpensive storage space, offering a traditional file system interface for easy integration with checkpointing applications. This paper presents the architecture of our checkpoint storage system, key write optimizations for high-speed I/O, support for increme...

  4. Virtual Desktop under Cloud Architecture%云架构下的虚拟化桌面

    Institute of Scientific and Technical Information of China (English)

    苏玉成; 蒋昆; 郭江博; 徐家富; 任斌; 张亚娜

    2014-01-01

    目的:提高医院办公电脑的维修效率和数据的安全性。方法对医院现有计算机设备维修业务流程进行优化,并结合医院云架构平台建设虚拟化桌面。结果通过规划医院云架构下的虚拟化桌面的建设,在不影响业务人员工作的情况下,提高了办公效率和信息安全,减少了设备的维修时间。结论该项目的实施为虚拟化桌面在医院环境下应用进行了探索。%Objective To improve the data security and maintenance efifciency of ofifce computers in the hospital. Methods To optimize the maintenance business process of existing computers and establish the virtual desktop based on cloud architecture platform in the hospital. Results The establishment of virtual desktop under cloud architecture has improved the office efficiency and information safety and has reduced the maintenance time of ofifce computers without prejudice to the work of business personnel. Conclusion The implementation of the project can provide exploration information for the application of virtual desktop in hospitals.

  5. An Introduction to Version Control Using GitHub Desktop

    OpenAIRE

    Daniel van Strien

    2016-01-01

    In this lesson you will be introduced to the basics of version control, understand why it is useful and implement basic version control for a plain text document using GitHub Desktop. By the end of this lesson you should understand: * what version control is and why it can be useful * the differences between Git and GitHub * how to implement version control using ‘GitHub Desktop,’ a Graphical User Interface for GitHub * be aware of other resources that will help you imple...

  6. An Introduction to Version Control Using GitHub Desktop

    Directory of Open Access Journals (Sweden)

    Daniel van Strien

    2016-06-01

    Full Text Available In this lesson you will be introduced to the basics of version control, understand why it is useful and implement basic version control for a plain text document using GitHub Desktop. By the end of this lesson you should understand: * what version control is and why it can be useful * the differences between Git and GitHub * how to implement version control using ‘GitHub Desktop,’ a Graphical User Interface for GitHub * be aware of other resources that will help you implement version control in your academic writing

  7. Simulation of scanning transmission electron microscope images on desktop computers

    Energy Technology Data Exchange (ETDEWEB)

    Dwyer, C., E-mail: christian.dwyer@mcem.monash.edu.au [Monash Centre for Electron Microscopy, Department of Materials Engineering, Monash University, Victoria 3800 (Australia)

    2010-02-15

    Two independent strategies are presented for reducing the computation time of multislice simulations of scanning transmission electron microscope (STEM) images: (1) optimal probe sampling, and (2) the use of desktop graphics processing units. The first strategy is applicable to STEM images generated by elastic and/or inelastic scattering, and requires minimal effort for its implementation. Used together, these two strategies can reduce typical computation times from days to hours, allowing practical simulation of STEM images of general atomic structures on a desktop computer.

  8. Student Behavioural Intentions to Use Desktop Video Conferencing in a Distance Course: Integration of Autonomy to the UTAUT Model

    Science.gov (United States)

    Lakhal, Sawsen; Khechine, Hager; Pascot, Daniel

    2013-01-01

    The aim of this study was to examine psychological factors which could influence acceptance and use of the desktop video conferencing technology by undergraduate business students. Based on the Unified Theory of Acceptance and Use of Technology, this study tested a theoretical model encompassing seven variables: behavioural intentions to use…

  9. 基于DSP2812的桌面3D打印机控制系统实现%Realization of Desktop 3D Printer Control System Based on DSP2812

    Institute of Scientific and Technical Information of China (English)

    时云; 梁宇; 张成林; 王卓; 王联凤; 王力; 田海林

    2016-01-01

    以DSP2812数字信号处理芯片为核心控制器,设计了一种桌面3D打印机控制系统,应用DSP2812中的通用寄存器生成的非对称式脉冲宽度调制(PWM)波形结合 DSP2812的通用输入/输出(I/O)口控制步进电机驱动芯片,进而实现步进电机的速率和位移控制;同时还创新性地应用DSP2812的通用数字I/O 口实现双向的两线连续总线(I2 C)功能,实现对步进电机的细分控制,从而控制步进电机的启动电流,降低系统功耗,提高步进电机的控制精度及稳定性。%A control system of desktop 3D printer was designed with DSP2812 digital signal processing chip as the core controller.By generating non-symmetric pulse width modulation (PWM)waveform with the general-purpose registers of the DSP2812,and using general-purpose input/output (I/O)port to control the stepper motor driver chip,the velocity and displacement control of the stepper motor was achieved.Another innovative application was using DSP2812’s general-purpose digital I/O port to achieve universal inter-integrated circuit (I2 C)function, and then to control the stepper motor’s starting current,which could reduce system power consumption and improve control accuracy and stability of the stepper motor.

  10. Automated Ply Inspection (API) for AFP Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Automated Ply Inspection (API) system autonomously inspects layups created by high speed automated fiber placement (AFP) machines. API comprises a high accuracy...

  11. Study on the Desktop Virtualization System Architecture of Kunming Power Supply Bureau%供电局桌面虚拟化系统架构研究

    Institute of Scientific and Technical Information of China (English)

    谢群

    2014-01-01

    This paper introduces in the context of cloud computing, Kunming power supply bureau with the help of IAAS ( infra-structure as a service,infrastructure as a service) based resource platform provides,perfect desktop virtualization and cloud platform integration,similar to the SAAS ( Software-as-a-service,software as a service) like DAAS ( Desktop As a Service, desktop as a service),the desktop as a service on demand,whenever and wherever possible,fast and safe delivery to any user complete desktop experience.%介绍了在云计算的背景下,某供电局借助于IAAS ( infrastructure as a service,基础设施即服务)提供的基础资源平台,桌面虚拟化和云平台的融合,实现类似于SAAS ( Software-as-a-service,软件即服务)一样的DAAS ( Desktop As a Service,桌面即服务),将桌面作为一种按需服务,安全快速地向任何用户提供服务。

  12. Adaptive runtime for a multiprocessing API

    Energy Technology Data Exchange (ETDEWEB)

    Antao, Samuel F.; Bertolli, Carlo; Eichenberger, Alexandre E.; O' Brien, John K.

    2016-10-11

    A computer-implemented method includes selecting a runtime for executing a program. The runtime includes a first combination of feature implementations, where each feature implementation implements a feature of an application programming interface (API). Execution of the program is monitored, and the execution uses the runtime. Monitor data is generated based on the monitoring. A second combination of feature implementations are selected, by a computer processor, where the selection is based at least in part on the monitor data. The runtime is modified by activating the second combination of feature implementations to replace the first combination of feature implementations.

  13. Adaptive runtime for a multiprocessing API

    Energy Technology Data Exchange (ETDEWEB)

    Antao, Samuel F.; Bertolli, Carlo; Eichenberger, Alexandre E.; O' Brien, John K.

    2016-11-15

    A computer-implemented method includes selecting a runtime for executing a program. The runtime includes a first combination of feature implementations, where each feature implementation implements a feature of an application programming interface (API). Execution of the program is monitored, and the execution uses the runtime. Monitor data is generated based on the monitoring. A second combination of feature implementations are selected, by a computer processor, where the selection is based at least in part on the monitor data. The runtime is modified by activating the second combination of feature implementations to replace the first combination of feature implementations.

  14. 基于Windows API的异步串口通信软件设计%Software Design of Asynchronous Serial Communication Based on Windows API

    Institute of Scientific and Technical Information of China (English)

    黄晓波

    2011-01-01

    Serial port is a common data transmission channel between PC and external serialequipment. When controls of the third party in VC+ + 6. 0 are utilized to realize serial communication, the behavior of real-time is poor and the utilization of system resources is insufficient. In order to improve the speed of serial communication and resource utilization, Windows API function and design concept of asynchronous serial communication based on the multi-thread tecnology and custom message mechanismin are adopted. The methods of developing the multi-thread asynchronous serial communication software in Win32 OS are analyzed. The main thread is the manager of the data acquisition program. The serial port real-time monitoring is implemented in the background by serial port monitoring thread. A stable communication result was achieved.%串口是常用的计算机与外部串行设备之间的教据传输通道,在VC++ 6.0中利用第三方控件实现串口通信时实时性较差,系统资源利用不足,为了提高串口通信的速度和资源利用率,软件采用Windows API函数并基于多线程技术和自定义消息机制的异步串口通信的设计理念,结合串口通信的机理和多线程同步技术,分析了Win32系统下多线程异步串口通信软件的开发方法.软件主线程是数据采集程序的管理者,串口监测线程(辅助线程)在后台对串口进行实时监视,获得了良好稳定的通信效果.

  15. 基于百度地图API的停车场查寻系统的设计%Design of Finding Parking System Based on Baidu Map API

    Institute of Scientific and Technical Information of China (English)

    肖文汉; 吴孝斌; 曹莹莹; 于建江

    2014-01-01

    随着城市汽车的拥有量不断增加,停车场缺少等问题给人们带来了诸多不便。传统的通过人工搜索、电话咨询、电台广播等寻找停车场的方法效率不高。基于百度地图开放API与ASP. NET Web应用开发技术,设计并实现了一个基于百度地图的停车场查询系统。该系统采用B/S结构,客户端采用ASP. NET AJAX技术,数据库采用SQL Server。测试结果表明,该系统正确查找率高于90%,响应时间明显优于电话咨询等传统方式。在3G网络以及智能手机普及的今天,该系统可以有效地帮助人们快速找到停车场,有益于智能交通,智慧城市的建设。%The increasing urban car brings the problem of how to find a parking lot. Looking for parking through traditional manual searching,phone calls and radio broadcasting is inefficient. Based on Baidu Map API and ASP. NET Web development technology, a finding parking system is designed and implemented. This system adopts B/S architecture,uses ASP. NET AJAX in client and chooses SQL Server as database. Test results show that the system's success rate is higher than 90%,the response time is significantly shorter than telephone counseling and other traditional methods. Today,the 3G network and smart phone are popular,the system can effectively help people to find parking quickly,which is good for intelligent transportation and smart city construction.

  16. MedlinePlus® Everywhere: Access from Your Phone, Tablet or Desktop

    Science.gov (United States)

    ... gov/responsivefull.html MedlinePlus® Everywhere: Access from Your Phone, Tablet or Desktop To use the sharing features ... consistent user experience from a desktop, tablet, or phone. All users, regardless of how they access MedlinePlus, ...

  17. A Desktop Virtual Reality Earth Motion System in Astronomy Education

    Science.gov (United States)

    Chen, Chih Hung; Yang, Jie Chi; Shen, Sarah; Jeng, Ming Chang

    2007-01-01

    In this study, a desktop virtual reality earth motion system (DVREMS) is designed and developed to be applied in the classroom. The system is implemented to assist elementary school students to clarify earth motion concepts using virtual reality principles. A study was conducted to observe the influences of the proposed system in learning.…

  18. Evaluation and Customization of Different Open Source Desktop GIS Software

    Institute of Scientific and Technical Information of China (English)

    QIU Ruqiong; LI Bing

    2012-01-01

    This paper gave a general evaluation on existing three popular free and open source desktop GIS projects,according to the selected evaluation criteria.To further the understanding of the open source software,this paper also presented a customization example of QGIS with python and PyQT.

  19. Using Desktop Virtual Environments To Investigate the Role of Landmarks.

    Science.gov (United States)

    Jansen-Osmann, Petra

    2002-01-01

    Discusses research in spatial cognition that uses computer-simulated three dimensional environments and evaluates the use of virtual desktop environments by replicating an experiment which was formerly done in a laboratory or real world setting. Investigates the role of landmarks when acquiring route knowledge in a system of paths. (Author/LRW)

  20. Creative Computer Detective: The Basics of Teaching Desktop Publishing.

    Science.gov (United States)

    Slothower, Jodie

    Teaching desktop publishing (dtp) in college journalism classes is most effective when the instructor integrates into specific courses four types of software--a word processor, a draw program, a paint program and a layout program. In a course on design and layout, the instructor can demonstrate with the computer how good design can be created and…

  1. Advances in parallel computer technology for desktop atmospheric dispersion models

    Energy Technology Data Exchange (ETDEWEB)

    Bian, X.; Ionescu-Niscov, S.; Fast, J.D. [Pacific Northwest National Lab., Richland, WA (United States); Allwine, K.J. [Allwine Enviornmental Serv., Richland, WA (United States)

    1996-12-31

    Desktop models are those models used by analysts with varied backgrounds, for performing, for example, air quality assessment and emergency response activities. These models must be robust, well documented, have minimal and well controlled user inputs, and have clear outputs. Existing coarse-grained parallel computers can provide significant increases in computation speed in desktop atmospheric dispersion modeling without considerable increases in hardware cost. This increased speed will allow for significant improvements to be made in the scientific foundations of these applied models, in the form of more advanced diffusion schemes and better representation of the wind and turbulence fields. This is especially attractive for emergency response applications where speed and accuracy are of utmost importance. This paper describes one particular application of coarse-grained parallel computer technology to a desktop complex terrain atmospheric dispersion modeling system. By comparing performance characteristics of the coarse-grained parallel version of the model with the single-processor version, we will demonstrate that applying coarse-grained parallel computer technology to desktop atmospheric dispersion modeling systems will allow us to address critical issues facing future requirements of this class of dispersion models.

  2. Versatile Desktop Experiment Module (DEMo) on Heat Transfer

    Science.gov (United States)

    Minerick, Adrienne R.

    2010-01-01

    This paper outlines a new Desktop Experiment Module (DEMo) engineered for a chemical engineering junior-level Heat Transfer course. This new DEMo learning tool is versatile, fairly inexpensive, and portable such that it can be positioned on student desks throughout a classroom. The DEMo system can illustrate conduction of various materials,…

  3. Designing for Communication: The Key to Successful Desktop Publishing.

    Science.gov (United States)

    McCain, Ted D. E.

    Written for those who are new to design and page layout, this book focuses on providing novice desktop publishers with an understanding of communication, graphic design, typography, page layout, and page layout techniques. The book also discusses how people read, design as a consequence of understanding, and the principles of page layout. Chapters…

  4. The Virtual Desktop: Options and Challenges in Selecting a Secure Desktop Infrastructure Based on Virtualization

    Science.gov (United States)

    2011-10-01

    specific models of devices. Details of the policy restrictions that can be placed on virtual images are product specific. As an example, the policies...DRDC-VALCARTIER- ECR -2004-232, External Client Report, September 2004. [8] Wikipedia, Comparison of open source and closed source, http...required. Identifiers, such as equipment model designation, trade name, military project code name, geographic location may also be included. If possible

  5. Desktop Publishing: Organizational Considerations for Adoption and Implementation. TDC Research Report No. 6.

    Science.gov (United States)

    Lee, Paul

    This report explores the implementation of desktop publishing in the Minnesota Extension Service (MES) and provides a framework for its implementation in other organizations. The document begins with historical background on the development of desktop publishing. Criteria for deciding whether to purchase a desktop publishing system, advantages and…

  6. Applications and Challenges of Private Desktop Cloud%私有桌面云的应用与挑战

    Institute of Scientific and Technical Information of China (English)

    余忠斌; 姜帅

    2013-01-01

      随着云计算技术的不断完善和推广使用,桌面云作为云计算的一种应用形态越来越受到关注。文章从桌面云的基本原理入手,通过对企业应用环境实地考察分析,设计出基于桌面云技术、适合企业实际情况的私有桌面云平台,为企业在数据安全、灵活接入管理、系统稳定性及运营成本等方面带来明显改进。%With the constant improvement and using of cloud computing technology, desktop cloud as an application form of cloud computing attracts more and more attention. Beginning with the basic principle of desktop cloud, this paper analyzes the application environments in enterpries, designs a private desktop cloud platform which is based on desktop cloud technology and suitable for the business practical situation and could improve data safety, flexibly access management, system stability, operation cost and so on.

  7. A knowledge discovery object model API for Java

    Directory of Open Access Journals (Sweden)

    Jones Steven JM

    2003-10-01

    Full Text Available Abstract Background Biological data resources have become heterogeneous and derive from multiple sources. This introduces challenges in the management and utilization of this data in software development. Although efforts are underway to create a standard format for the transmission and storage of biological data, this objective has yet to be fully realized. Results This work describes an application programming interface (API that provides a framework for developing an effective biological knowledge ontology for Java-based software projects. The API provides a robust framework for the data acquisition and management needs of an ontology implementation. In addition, the API contains classes to assist in creating GUIs to represent this data visually. Conclusions The Knowledge Discovery Object Model (KDOM API is particularly useful for medium to large applications, or for a number of smaller software projects with common characteristics or objectives. KDOM can be coupled effectively with other biologically relevant APIs and classes. Source code, libraries, documentation and examples are available at http://www.bcgsc.ca/bioinfo/software.

  8. 基于Google Earth3D原生COM API的二次开发%Based on the Google Earth3D Native COM API Two Development

    Institute of Scientific and Technical Information of China (English)

    唐小桃; 陆元会

    2012-01-01

    给出了Google Earth原生COM API调用的步骤和基本方法,实现了Google Earth的登录、漫游、绘图、查找、UI控制等基本的功能,突破了Google Earth API只能通过Javascript API调用的限制,并给出Google Earth API Javascript API翻译为通用语言的一般方法.

  9. Feasibility of Bioprinting with a Modified Desktop 3D Printer.

    Science.gov (United States)

    Goldstein, Todd A; Epstein, Casey J; Schwartz, John; Krush, Alex; Lagalante, Dan J; Mercadante, Kevin P; Zeltsman, David; Smith, Lee P; Grande, Daniel A

    2016-12-01

    Numerous studies have shown the capabilities of three-dimensional (3D) printing for use in the medical industry. At the time of this publication, basic home desktop 3D printer kits can cost as little as $300, whereas medical-specific 3D bioprinters can cost more than $300,000. The purpose of this study is to show how a commercially available desktop 3D printer could be modified to bioprint an engineered poly-l-lactic acid scaffold containing viable chondrocytes in a bioink. Our bioprinter was used to create a living 3D functional tissue-engineered cartilage scaffold. In this article, we detail the design, production, and calibration of this bioprinter. In addition, the bioprinted cells were tested for viability, proliferation, biochemistry, and gene expression; these tests showed that the cells survived the printing process, were able to continue dividing, and produce the extracellular matrix expected of chondrocytes.

  10. TCP/UDP下一种网络透明传输服务编程接口实现方法%Implementation of a Service API on Transparent Network Communication Programming Based on TCP/UDP

    Institute of Scientific and Technical Information of China (English)

    何波玲; 隋菱歌

    2011-01-01

    To write network communication code based on TCP/UDP,you must understand some network communication concepts such as IP address,port,socket,TCP/UDP protocols etc.This paper implemented a service API(Application Programming Interface) that encapsulate all network communication concepts and make TCP programming and UDP programming with the same mode.The results show that the API can make network communication programming very easily with no network concepts and supposes real-time and reliable communication and multi-NIC(Network Interface Card) in same host.%使用在TCP/UDP协议进行网络通信,会涉及IP地址、端口号、套接字、TCP/UDP协议等网络通信概念,而且TCP传输和UDP传输的编程模式是不同的,对网络通信概念进行了封装,实现了一个网络通信透明传输服务系统,且TCP传输和UDP传输具有相同的编程模式.使用表明,用户无需了解网络通信概念,即可使用该系统进行通信编程,使用极为方便,实现网络通信的实时传输、可靠传输和同一主机的多网卡支持.

  11. Research and implementation of campus electronic map based on ArcGIS Flex API%基于ArcGIS Flex API的校园电子地图研究与实现

    Institute of Scientific and Technical Information of China (English)

    姬英杰; 徐鹏; 杨怀卿

    2014-01-01

    将 ArcGIS Server 地图服务、WebServer 服务集成于 Adobe Flash Builder 4下,研究开发了基于 ArcGIS Flex API 的校园电子地图展示软件。该软件提供了山西某大学详细的地图信息,不仅拥有常规地图导航、支持属性模糊查询空间要素等功能,而且还对任意两个热点间最短路径分析功能进行合理定制,对校园风光和人文历史的展示产生了很好的效果。%By the integration of the ArcGIS Server map service and WebServer service in Adobe Flash Builder 4, the paper researches and develops campus electronic map display software based on ArcGIS Flex API. The software provides a university in Shanxi detailed map information, it not only has a conventional map navigation functions, supports attribute fuzzy query spatial features and other functions, but also reasonably customizes the analysis functions on the shortest path between any two hotspots. The software produces very good results the campus scenery and cultural history of showing.

  12. Online behavior from desktop and mobile devices are connected

    OpenAIRE

    Nylander, Stina

    2010-01-01

    Cell phones and other mobile devices are used to access the Internet even at home and at work where computers are easily available. They are no longer a mere backup to the computer. This means that it makes little sense to study Internet access from mobile devices separate from other Internet access. We need new methods that encompass online behavior from desktop computers and mobile devices as well as stationary and mobile online behavior.

  13. Macelignan inhibits bee pathogenic fungi Ascophaera apis growth through HOG1 pathway

    Directory of Open Access Journals (Sweden)

    Y.K. Shin

    2016-01-01

    Full Text Available Ascosphaera apis is a bee pathogen that causes bee larvae infection disease, to which treatment is not yet well investigated. The aim of this study was to investigate antifungal susceptibility in vitro against A. apis and to identify a new antifungal agent for this pathogen through minimal inhibitory concentration (MIC assay and western blot analysis. Macelignan had 1.56 and 3.125 μg/mL MIC against A. apis after 24 and 48 h, respectively, exhibiting the strongest growth inhibition against A. apis among the tested compounds (corosolic acid, dehydrocostus lactone, loganic acid, tracheloside, fangchinoline and emodin-8-O-β-D-glucopyranoside. Furthermore, macelignan showed a narrow-ranged spectrum against various fungal strains without any mammalian cell cytotoxicity. In spite of miconazole having powerful broad-ranged anti-fungal activity including A. apis, it demonstrated strong cytotoxicity. Therefore, even if macelignan alone was effective as an antifungal agent to treat A. apis, combined treatment with miconazole was more useful to overcome toxicity, drug resistance occurrence and cost effectiveness. Finally, HOG1 was revealed as a target molecule of macelignan in the anti-A. apis activity by inhibiting phosphorylation using S. cerevisiae as a model system. Based on our results, macelignan, a food-grade antimicrobial compound, would be an effective antifungal agent against A. apis infection in bees.

  14. Influence of humidity on the phase behavior of API/polymer formulations.

    Science.gov (United States)

    Prudic, Anke; Ji, Yuanhui; Luebbert, Christian; Sadowski, Gabriele

    2015-08-01

    Amorphous formulations of APIs in polymers tend to absorb water from the atmosphere. This absorption of water can induce API recrystallization, leading to reduced long-term stability during storage. In this work, the phase behavior of different formulations was investigated as a function of relative humidity. Indomethacin and naproxen were chosen as model APIs and poly(vinyl pyrrolidone) (PVP) and poly(vinyl pyrrolidone-co-vinyl acetate) (PVPVA64) as excipients. The formulations were prepared by spray drying. The water sorption in pure polymers and in formulations was measured at 25°C and at different values of relative humidity (RH=25%, 50% and 75%). Most water was absorbed in PVP-containing systems, and water sorption was decreasing with increasing API content. These trends could also be predicted in good agreement with the experimental data using the thermodynamic model PC-SAFT. Furthermore, the effect of absorbed water on API solubility in the polymer and on the glass-transition temperature of the formulations was predicted with PC-SAFT and the Gordon-Taylor equation, respectively. The absorbed water was found to significantly decrease the API solubility in the polymer as well as the glass-transition temperature of the formulation. Based on a quantitative modeling of the API/polymer phase diagrams as a function of relative humidity, appropriate API/polymer compositions can now be selected to ensure long-term stable amorphous formulations at given storage conditions.

  15. API E MIELE NEL MEDITERRANEO ANTICO

    Directory of Open Access Journals (Sweden)

    Matteo Bormetti

    2014-09-01

    Full Text Available L’importanza del miele come sostanza culturalmente ed economicamente rilevante nel mondo antico non è stata ancora del tutto indagata. Il miele e le api sono nondimeno presenze assidue e trasversali ai generi e alle tipologie di fonti antiche greche e romane, ed è pertanto da esse che una ricerca sull’argomento deve partire. I manufatti, le tecniche e i concetti descritti dagli antichi devono però essere relazionati con cautela al materiale archeologico rinvenuto, per fare ciò pare indispensabile un approccio che tenga conto delle nozioni biologiche, etologiche e zootecniche di base. Attraverso quest’ottica sono state ricapitolate le evidenze materiali provenienti dal bacino del Mediterraneo e concernenti gli strumenti e le strutture relative all’apicoltura, dalle arnie agli apiari, peril lungo arco cronologico che va dall’età del bronzo alla tarda antichità. Ciò è possibile per la tematica apicola grazie alla conservatività delle tecniche, strettamente legate ai severi dettami della natura fino alla rivoluzione ottocentesca delle arnie razionali a telai mobili del reverendo Langstroth. Sono inoltre analizzati gli utilizzi più frequenti del miele per come descritti dalle fonti letterarie nonché le implicazioni di api e miele nella ritualità e nel simbolismo della morte, del genere e della regalità, sebbene i risultati siano scarsi data la povertà dei riscontri archeologici e la limitata attenzione di cui questo argomento ha fin ora goduto.

  16. DIaaS: Resource Management System for the Intra-Cloud with On-Premise Desktops

    Directory of Open Access Journals (Sweden)

    Hyun-Woo Kim

    2017-01-01

    Full Text Available Infrastructure as a service with desktops (DIaaS based on the extensible mark-up language (XML is herein proposed to utilize surplus resources. DIaaS is a traditional surplus-resource integrated management technology. It is designed to provide fast work distribution and computing services based on user service requests as well as storage services through desktop-based distributed computing and storage resource integration. DIaaS includes a nondisruptive resource service and an auto-scalable scheme to enhance the availability and scalability of intra-cloud computing resources. A performance evaluation of the proposed scheme measured the clustering performance time for surplus resource utilization. The results showed improvement in computing and storage services in a connection of at least two computers compared to the traditional method for high-availability measurement of nondisruptive services. Furthermore, an artificial server error environment was used to create a clustering delay for computing and storage services and for nondisruptive services. It was compared to the Hadoop distributed file system (HDFS.

  17. Análise de agrupamento, com base na composição físico-química, de amostras de méis produzidos por Apis mellifera L. no Estado de São Paulo Cluster analysis, with basis in physico-chemical composition, of samples of honey produced by Apis mellifera L. in São Paulo State

    Directory of Open Access Journals (Sweden)

    Luís Carlos Marchini

    2005-03-01

    Full Text Available A composição do mel depende, basicamente, da composição do néctar de cada espécie vegetal produtora, conferindo-lhe características específicas enquanto que as condições climáticas e o manejo do apicultor têm influência menor sobre essas características. A presente pesquisa, desenvolvida com amostras de méis de Apis mellifera coletadas diretamente dos produtores de 84 municípios do Estado de São Paulo teve o objetivo de verificar, com base em características físico-químicas, como se agrupam as amostras de méis silvestres e de eucaliptos. Dentre as 121 amostras de méis analisadas as de eucaliptos e as silvestres formam grupos distintos quanto aos caracteres físico-químicos, o que confirma que a origem floral interfere decisivamente nas características dos méis. Pela análise dos componentes principais, pode-se verificar que os caracteres que mais influenciaram no agrupamentos das amostras de méis foram condutividade elétrica e quantidade de K, no eixo X e índice de formol e umidade, no eixo Y.The honey composition depends, basically, of the nectar composition of each vegetal species. This composition confer to it specific characteristics while that the climatic conditions and the beekeeper handling have lesser influence on these features. The present research, developed with samples of Apis mellifera honeys, collected directly of the producers from 84 locations of the State of São Paulo, Brazil, had the objective of verifying, on the basis of physico-chemical characteristics, as the samples of wild and Eucalyptus honeys are grouped. Amongst the 121 samples analyzed the wild and Eucalyptus honeys form distinct groups with basis of the physico-chemical characteristics, what confirms that the floral origin intervenes decisively with the honey characteristics. For the analysis of the main components, it can be verified that the characters that had more influenced in the groupings of the honey samples were the electric

  18. Automated information extraction from web APIs documentation

    OpenAIRE

    Ly, Papa Alioune; Pedrinaci, Carlos; Domingue, John

    2012-01-01

    A fundamental characteristic of Web APIs is the fact that, de facto, providers hardly follow any standard practices while implementing, publishing, and documenting their APIs. As a consequence, the discovery and use of these services by third parties is significantly hampered. In order to achieve further automation while exploiting Web APIs we present an approach for automatically extracting relevant technical information from the Web pages documenting them. In particular we have devised two ...

  19. Interoperability of Linux and Windows in Desktop Domain%Linux与Windows在桌面领域的互操作性

    Institute of Scientific and Technical Information of China (English)

    王亚军

    2012-01-01

    Linux和Windows都是计算机操作系统领域中的技术热点,两者实现互操作有利于在竞争中共同推动操作系统技术向纵深发展.针对Linux和Windows在桌面领域中的互操作问题,文中作了系统的阐述.在桌面领域,Linux和Windows可以采用API仿真等虚拟化技术或修改操作系统源代码的方法来互运行对方程序,可以采用开放、通用与统一的数据文件格式标准来互处理数据文件,可以采用内核空间文件系统机制或用户空间文件系统机制来互访问文件系统等.%Linux and Windows are both hot points in the academic field of computer technology. The interoperability of them two further expands their respective development area. On the other hand, some new technology problems are also produced. Focusing on the interoperability of Linux and Windows in desktop domain, this paper goes into a little more detail about these problems and their solutions. In desktop domain, the two operating systems can mutually run programs by adopting virtualization technologies such as API emulation or by altering source codes of operating systems, can mutually deal with data files by adopting open, common and unified data file format standards, and can mutually access file systems by adopting the mechanism of file system in kernel space or in user space.

  20. BusinessUSA Resource Access API

    Data.gov (United States)

    General Services Administration — BusinessUSA connects businesses to government services and information. The API provides access to resource abstracts including programs, services, data, events, and...

  1. AKTIVITAS ANTIOKSIDAN DAN EFEK HEPATOPROTEKTIF DAUN BAKAU API-API PUTIH

    Directory of Open Access Journals (Sweden)

    safrina dyah hardiningtyas

    2014-07-01

    Full Text Available Penelitian ini bertujuan untuk mendapatkan ekstrak kasar daun api-api putih yang memiliki aktivitas antioksidan terbaik, menentukan kandungan fitokimia dan efek Hepatoprotektif ekstrak kasar yang dipilih secara in vivo. Daun api-api putih diekstrak menggunakan tiga jenis pelarut, yakni metanol, etil asetat dan n-heksana. Dalam uji in vivo dilakukan evaluasi terhadap kadar malondialdehid (MDA, enzim aspartat transaminase (AST, enzim alanin transaminase (ALT, dan histopatologi. Hasil penelitian menunjukkan bahwa ekstraksi daun api-api putih dengan pelarut etil asetat menghasilkan aktivitas antioksidan terbaik dengan kandungan fitokimia terdiri dari flavonoid dan steroid/triterpenoid. Pemberian ekstrak etil asetat daun api-api putih pada tikus yang telah diinduksi CCl4 dapat menormalkan berbagai parameter biokimia stres oksidatif (kadar MDA, AST, dan ALT dibandingkan dengan standar Silymarin. Ekstrak daun api-api putih berpotensi untuk melindungi hati tikus dari kerusakan oksidatif yang diinduksi CCl4. Efek Hepatoprotektif ekstrak daun api-api putih berkorelasi dengan aktivitas antioksidannya.Kata kunci: antioksidan, Avicennia marina, ekstrak, hepatoprotektor

  2. The Ruby UCSC API: accessing the UCSC genome database using Ruby

    Directory of Open Access Journals (Sweden)

    Mishima Hiroyuki

    2012-09-01

    Full Text Available Abstract Background The University of California, Santa Cruz (UCSC genome database is among the most used sources of genomic annotation in human and other organisms. The database offers an excellent web-based graphical user interface (the UCSC genome browser and several means for programmatic queries. A simple application programming interface (API in a scripting language aimed at the biologist was however not yet available. Here, we present the Ruby UCSC API, a library to access the UCSC genome database using Ruby. Results The API is designed as a BioRuby plug-in and built on the ActiveRecord 3 framework for the object-relational mapping, making writing SQL statements unnecessary. The current version of the API supports databases of all organisms in the UCSC genome database including human, mammals, vertebrates, deuterostomes, insects, nematodes, and yeast. The API uses the bin index—if available—when querying for genomic intervals. The API also supports genomic sequence queries using locally downloaded *.2bit files that are not stored in the official MySQL database. The API is implemented in pure Ruby and is therefore available in different environments and with different Ruby interpreters (including JRuby. Conclusions Assisted by the straightforward object-oriented design of Ruby and ActiveRecord, the Ruby UCSC API will facilitate biologists to query the UCSC genome database programmatically. The API is available through the RubyGem system. Source code and documentation are available at https://github.com/misshie/bioruby-ucsc-api/ under the Ruby license. Feedback and help is provided via the website at http://rubyucscapi.userecho.com/.

  3. Design and Application of Highway WebGIS Based on Google Maps API%基于Google Maps API的高速公路WebGIS设计与应用

    Institute of Scientific and Technical Information of China (English)

    苏晓蓓; 杨铭; 张高峰; 王志

    2011-01-01

    设计了基于Google Maps API技术的WebGIS系统,同时讨论了Google Maps的定制方法和功能设计,给出了定制设计的部分代码。文章结合高速公路WebGIS的设计实例,给出了整体系统示意图并对系统的各项功能做了详细介绍。%A WebGIS system based on Google Maps API techniques was designed in this paper.At the same time,how to custom Google maps and design functions were discussed.Combined the example of a Highway WebGIS,the paper gave an overall system diagram and introduced the various functions in details.

  4. Air quality daily report at Baosteel based on API evaluation process%基于API评价方法的宝钢厂区空气质量日报

    Institute of Scientific and Technical Information of China (English)

    方方; 李伟

    2011-01-01

    本文就宝钢的空气质量自动监测系统的发展历史进行回顾,主要介绍目前、运行的空气自动监测系统的组成、数据流向,着重介绍基于API评价方法的宝钢空气质量日报,并探讨宝钢、宝山区和上海市的同期空气质量状况.%In this paper, air quality automatic monitoring system development at Baosteel is reviewed. The structure and data flow of air automatic monitoring system are mainly introduced. The air quality daily report at Baosteel based on the API evaluation method is emphatically introduced. In addition the air quality status at Baosteel, Baoshan District and Shanghai over the same period is compared.

  5. Gigabits to the Desktop: Installing tomorrow`s networks today

    Energy Technology Data Exchange (ETDEWEB)

    Kuhfuss, T.C.; Phillips, P.T.

    1994-03-01

    Argonne is one of the US Department of Energy`s world class research institutions. Leading edge computing tools and networks allow Argonne to maintain and enhance this reputation. One current effort to deploy leading edge tools is the Argonne ``Gigabits to the Desktop`` project. While the delivering and using gigabits to the desktop is little more than a hope at this time, this paper will discuss the hurdles to achieving it and how to tear down as many hurdles as possible. Under this project, four distinct areas are being investigated and enhanced. This paper will discuss briefly the applications and tools that we see driving the requirement for gigabits to the desktop. It will touch on a functional description of our``ideal`` workstations, architectures and the candidates for the next generation network capable of delivering gigabits. Lastly, it will provide an in-depth analysis of physical layer options and attempt to prove that this area, while the least risky, must be done properly, with the proper media. This paper assumes one important point. It assumes that bandwidth is essentially free. We will discuss network architectures and physical installation recommendations which have a fixed cost. However on a campus, there is no marginal cost for additional packets on these networks once the network infrastructure is installed. This point is important when extrapolating our conclusions to the wide area. The marginal cost of a packet sent to a commercial network is usually non zero. This fact may prove to be a great hindrance in migrating the applications mentioned beyond the organizational boundaries.

  6. Desktop computer graphics for RMS/payload handling flight design

    Science.gov (United States)

    Homan, D. J.

    1984-01-01

    A computer program, the Multi-Adaptive Drawings, Renderings and Similitudes (MADRAS) program, is discussed. The modeling program, written for a desktop computer system (the Hewlett-Packard 9845/C), is written in BASIC and uses modular construction of objects while generating both wire-frame and hidden-line drawings from any viewpoint. The dimensions and placement of objects are user definable. Once the hidden-line calculations are made for a particular viewpoint, the viewpoint may be rotated in pan, tilt, and roll without further hidden-line calculations. The use and results of this program are discussed.

  7. Effective Web and Desktop Retrieval with Enhanced Semantic Spaces

    Science.gov (United States)

    Daoud, Amjad M.

    We describe the design and implementation of the NETBOOK prototype system for collecting, structuring and efficiently creating semantic vectors for concepts, noun phrases, and documents from a corpus of free full text ebooks available on the World Wide Web. Automatic generation of concept maps from correlated index terms and extracted noun phrases are used to build a powerful conceptual index of individual pages. To ensure scalabilty of our system, dimension reduction is performed using Random Projection [13]. Furthermore, we present a complete evaluation of the relative effectiveness of the NETBOOK system versus the Google Desktop [8].

  8. IMPACTS OF APPLICATION USAGE AND LOCAL HARDWARE ON THE THROUGHPUT OF COMPUTER NETWORKS WITH DESKTOP VIRTUALIZATION

    Directory of Open Access Journals (Sweden)

    Vitor Chaves De Oliveira

    2013-01-01

    Full Text Available Currently, virtualization solutions are employed in the vast majority of organizations around the world. The reasons for this are the benefits gained by the approach, focusing on increases in security, availability and data integrity. These privileges are also present in a new technique, which emerges from this same concept and is called desktop virtualization. This method, compelled by these advantages, has grown considerably and is likely to be implemented on more than three-quarters of organizations before 2014. As it is a technique based on physical client server architecture, it conducts all its actions on a local computer and responds to user interaction, through clients that are physically elsewhere. This means that the technique depends on the communication network which makes the interaction possible. Therefore, the importance of the network is increased and it is important to study its behavior compared to a traditional desktop solution, that is, a local solution. This article demonstrates the impact related to a Quality of Service (QoS parameter, throughput, which suffered great alterations depending on the implemented computational environment. Concomitantly, other results are expressed concerning the Quality of Experience (QoE decay with a thin client and a significant benefit of virtualization on the QoS, when remote access is required.

  9. The Proteins API: accessing key integrated protein and genome information.

    Science.gov (United States)

    Nightingale, Andrew; Antunes, Ricardo; Alpi, Emanuele; Bursteinas, Borisas; Gonzales, Leonardo; Liu, Wudong; Luo, Jie; Qi, Guoying; Turner, Edd; Martin, Maria

    2017-04-05

    The Proteins API provides searching and programmatic access to protein and associated genomics data such as curated protein sequence positional annotations from UniProtKB, as well as mapped variation and proteomics data from large scale data sources (LSS). Using the coordinates service, researchers are able to retrieve the genomic sequence coordinates for proteins in UniProtKB. This, the LSS genomics and proteomics data for UniProt proteins is programmatically only available through this service. A Swagger UI has been implemented to provide documentation, an interface for users, with little or no programming experience, to 'talk' to the services to quickly and easily formulate queries with the services and obtain dynamically generated source code for popular programming languages, such as Java, Perl, Python and Ruby. Search results are returned as standard JSON, XML or GFF data objects. The Proteins API is a scalable, reliable, fast, easy to use RESTful services that provides a broad protein information resource for users to ask questions based upon their field of expertise and allowing them to gain an integrated overview of protein annotations available to aid their knowledge gain on proteins in biological processes. The Proteins API is available at (http://www.ebi.ac.uk/proteins/api/doc).

  10. The MPO API: A tool for recording scientific workflows

    Energy Technology Data Exchange (ETDEWEB)

    Wright, John C., E-mail: jcwright@mit.edu [MIT Plasma Science and Fusion Center, Cambridge, MA (United States); Greenwald, Martin; Stillerman, Joshua [MIT Plasma Science and Fusion Center, Cambridge, MA (United States); Abla, Gheni; Chanthavong, Bobby; Flanagan, Sean; Schissel, David; Lee, Xia [General Atomics, San Diego, CA (United States); Romosan, Alex; Shoshani, Arie [Lawrence Berkeley Laboratory, Berkeley, CA (United States)

    2014-05-15

    Highlights: • A description of a new framework and tool for recording scientific workflows, especially those resulting from simulation and analysis. • An explanation of the underlying technologies used to implement this web based tool. • Several examples of using the tool. - Abstract: Data from large-scale experiments and extreme-scale computing is expensive to produce and may be used for high-consequence applications. The Metadata, Provenance and Ontology (MPO) project builds on previous work [M. Greenwald, Fusion Eng. Des. 87 (2012) 2205–2208] and is focused on providing documentation of workflows, data provenance and the ability to data-mine large sets of results. While there are important design and development aspects to the data structures and user interfaces, we concern ourselves in this paper with the application programming interface (API) – the set of functions that interface with the data server. Our approach for the data server is to follow the Representational State Transfer (RESTful) software architecture style for client–server communication. At its core, the API uses the POST and GET methods of the HTTP protocol to transfer workflow information in message bodies to targets specified in the URL to and from the database via a web server. Higher level API calls are built upon this core API. This design facilitates implementation on different platforms and in different languages and is robust to changes in the underlying technologies used. The command line client implementation can communicate with the data server from any machine with HTTP access.

  11. Evaluation of usefulness and availability for orthopedic surgery using clavicle fracture model manufactured by desktop 3D printer

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Wang Kyun [Dept. of Diagnostic Radiology, Cheongju Medical Center, Cheongju (Korea, Republic of)

    2014-09-15

    Usefulness and clinical availability for surgery efficiency were evaluated by conducting pre-operative planning with a model manufactured by desktop 3D printer by using clavicle CT image. The patient-customized clavicle fracture model was manufactured by desktop 3D printer of FDM wire laminated processing method by converting the CT image into STL file in Open Source DICOM Viewer Osirix. Also, the model of the original shape before damaged was restored and manufactured by Mirror technique based on STL file of not fractured clavicle of the other side by using the symmetry feature of the human body. For the model, the position and size, degree of the fracture was equally printed out. Using the clavicle model directly manufactured with low cost and less time in Department of Radiology is considered to be useful because it can reduce secondary damage during surgery and increase surgery efficiency with Minimal invasive percutaneous plate osteosynthesis(MIPO)

  12. Validation of the Parlay API through prototyping

    NARCIS (Netherlands)

    Hellenthal, J.W.; Planken, F.J.M.; Wegdam, M.

    2001-01-01

    The desire within the telecommunications world for new and faster business growth has been a major drive towards the development of open network API. Over the past 7 years several (semi) standardization groups have announced work on network API, including TINA-C, JAIN, IEEE P1520, INforum, 3GPP, JAI

  13. 基于Google Maps API的矢量化Web平台%A Vectorization Web Platform based on Google Maps API

    Institute of Scientific and Technical Information of China (English)

    付卫平; 郭建文; 刘鹏

    2011-01-01

    为了充分挖掘Google Maps在GIS专业领域的应用价值,以Google Maps与矢量数据的融合为出发点,运用Google Maps API、Ajax技术以及开源GDAL/OGR组件,开发了一个基于Web的矢量化平台。通过该平台,用户可以在Google Maps上实现矢量化操作并将结果保存为Shape格式矢量文件,也可将Shape文件加载至Google Maps上叠加显示,为用户提供了一种基于Google Maps的数据获取途径和矢量数据显示方法,体现了其在GIS专业领域的使用价值。%In order to give full play of application value of Google Maps in the region of GIS,regard integration of Google Maps and vector data as the starting point,developed a vectorization web platform by the use of Ajax and GDAL on the basis of Google Maps API.Through this platform,users can implement Google raster maps vectorization,save the results as ESRI Shape files and display user Shape data in vectorial mode on Google Maps.

  14. xAPI与基于Moodle的在线学习经历数据获取%Access to Online Learning Experience Data based on xAPI

    Institute of Scientific and Technical Information of China (English)

    胡建平

    2016-01-01

    在线学习的发展离不开规范的技术标准,但是早期的SCORM (Sharable Content Object Reference Model,可共享内容对象参考模型)技术标准已经不能适应目前的学习需求,而xAPI (Experience Application ProgrammingInterface,经验应用程序编程接口)的出现为在线教育带来了新的发展机遇.文章介绍了xAPI的基本功能、xAPI的核心Statement(声明)及xAPI的存储机制LRS (Learning Record Store,学习记录存储),并通过Moodle平台详细介绍了基于xAPI的在线学习经历数据的获取过程.文章指出,xAPI能更好地支持学习生态系统的建设、完善评价机制、促进个性化学习的实现,对在线教育具有积极意义.

  15. Cloud Computing and Virtual Desktop Infrastructures in Afloat Environments

    Science.gov (United States)

    2012-06-01

    INTENTIONALLY LEFT BLANK xiii LIST OF ACRONYMS AND ABBREVIATIONS AOR Area of Responsibility API Application Programming Interface BGAN ...Global Area Network The Broadband Global Area Network, or BGAN , is a global satellite Internet network system. The system utilizes the Internet...transfer, and remote surveillance, among others. [38] BGAN is a viable and suitable solution to linking nodes in an afloat cloud infrastructure for several

  16. Identification of Complete Repertoire of Apis florea Odorant Receptors Reveals Complex Orthologous Relationships with Apis mellifera.

    Science.gov (United States)

    Karpe, Snehal D; Jain, Rikesh; Brockmann, Axel; Sowdhamini, Ramanathan

    2016-09-26

    We developed a computational pipeline for homology based identification of the complete repertoire of olfactory receptor (OR) genes in the Asian honey bee species, Apis florea Apis florea is phylogenetically the most basal honey bee species and also the most distant sister species to the Western honey bee Apis mellifera, for which all OR genes had been identified before. Using our pipeline, we identified 180 OR genes in A. florea, which is very similar to the number of ORs identified in A. mellifera (177 ORs). Many characteristics of the ORs including gene structure, synteny of tandemly repeated ORs and basic phylogenetic clustering are highly conserved. The composite phylogenetic tree of A. florea and A. mellifera ORs could be divided into 21 clades which are in harmony with the existing Hymenopteran tree. However, we found a few nonorthologous OR relationships between both species as well as independent pseudogenization of ORs suggesting separate evolutionary changes. Particularly, a subgroup of the OR gene clade XI, which had been hypothesized to code cuticular hydrocarbon receptors showed a high number of species-specific ORs RNAseq analysis detected a total number of 145 OR transcripts in male and 162 in female antennae. Most of the OR genes were highly expressed on the female antennae. However, we detected five distinct male-biased OR genes, out of which three genes (AfOr11, AfOr18, AfOr170P) were shown to be male-biased in A. mellifera, too, thus corroborating a behavioral function in sex-pheromone communication.

  17. Multimedia architectures: from desktop systems to portable appliances

    Science.gov (United States)

    Bhaskaran, Vasudev; Konstantinides, Konstantinos; Natarajan, Balas R.

    1997-01-01

    Future desktop and portable computing systems will have as their core an integrated multimedia system. Such a system will seamlessly combine digital video, digital audio, computer animation, text, and graphics. Furthermore, such a system will allow for mixed-media creation, dissemination, and interactive access in real time. Multimedia architectures that need to support these functions have traditionally required special display and processing units for the different media types. This approach tends to be expensive and is inefficient in its use of silicon. Furthermore, such media-specific processing units are unable to cope with the fluid nature of the multimedia market wherein the needs and standards are changing and system manufacturers may demand a single component media engine across a range of products. This constraint has led to a shift towards providing a single-component multimedia specific computing engine that can be integrated easily within desktop systems, tethered consumer appliances, or portable appliances. In this paper, we review some of the recent architectural efforts in developing integrated media systems. We primarily focus on two efforts, namely the evolution of multimedia-capable general purpose processors and a more recent effort in developing single component mixed media co-processors. Design considerations that could facilitate the migration of these technologies to a portable integrated media system also are presented.

  18. SERVICE HANDBOOK FOR THE DESKTOP SUPPORT CONTRACT WIH IT DIVISION

    CERN Multimedia

    2000-01-01

    A Desktop Support Contract has been running since January 1999 to offer help to all users at CERN with problems that occur with their desktop computers. The contract is run conjointly by the Swedish Company WM-data and the Swiss company DCS.The contract is comprised of the Computing Helpdesk, a General Service for all parts of CERN and also Local Service for those divisions and groups that want faster response times and additional help with their specific computer environment.In order to describe what services are being offered, and also to give a better understanding of the structure of the contract, a Service Handbook has been created. The intended audience for the Service Handbook is everyone that is using the contract, i.e. users, managers and also the service staff inside the contract. In the handbook you will find what help you can get from the contract, how to get in touch with the contract, and also what response times you can expect. Since the computer environment at CERN is a never-changing entity, ...

  19. The Nimrod computational workbench: a case study in desktop metacomputing

    Energy Technology Data Exchange (ETDEWEB)

    Abramson, D.; Sosic, R. [Griffith Univ., Brisbane, QLD (Australia); Foster, I. [Argonne National Lab., IL (United States); Giddy, J. [Queensland Univ., St. Lucia, QLD (Australia); Lewis, A. [Griffith Univ., Brisbane, QLD (Australia); White, N. [Queensland Univ., St. Lucia, QLD (Australia)

    1996-12-31

    The coordinated use of geographically distributed computers, or metacomputing, can in principle provide more accessible and cost- effective supercomputing than conventional high-performance systems. However, we lack evidence that metacomputing systems can be made easily usable, or that there exist large numbers of applications able to exploit metacomputing resources. In this paper, we present work that addresses both these concerns. The basis for this work is a system called Nimrod that provides a desktop problem-solving environment for parametric experiments. We describe how Nimrod has been extended to support the scheduling of computational resources located in a wide-area environment, and report on an experiment in which Nimrod was used to schedule a large parametric study across the Australian Internet. The experiment provided both new scientific results and insights into Nimrod capabilities. We relate the results of this experiment to lessons learned from the I-WAY distributed computing experiment, and draw conclusions as to how Nimrod and I-WAY- like computing environments should be developed to support desktop metacomputing.

  20. 3d visualization of atomistic simulations on every desktop

    Science.gov (United States)

    Peled, Dan; Silverman, Amihai; Adler, Joan

    2013-08-01

    Once upon a time, after making simulations, one had to go to a visualization center with fancy SGI machines to run a GL visualization and make a movie. More recently, OpenGL and its mesa clone have let us create 3D on simple desktops (or laptops), whether or not a Z-buffer card is present. Today, 3D a la Avatar is a commodity technique, presented in cinemas and sold for home TV. However, only a few special research centers have systems large enough for entire classes to view 3D, or special immersive facilities like visualization CAVEs or walls, and not everyone finds 3D immersion easy to view. For maximum physics with minimum effort a 3D system must come to each researcher and student. So how do we create 3D visualization cheaply on every desktop for atomistic simulations? After several months of attempts to select commodity equipment for a whole room system, we selected an approach that goes back a long time, even predating GL. The old concept of anaglyphic stereo relies on two images, slightly displaced, and viewed through colored glasses, or two squares of cellophane from a regular screen/projector or poster. We have added this capability to our AViz atomistic visualization code in its new, 6.1 version, which is RedHat, CentOS and Ubuntu compatible. Examples using data from our own research and that of other groups will be given.

  1. Apoptosis inhibitor 5 (API-5; AAC-11; FIF) is upregulated in human carcinomas in vivo.

    Science.gov (United States)

    Koci, Lenka; Chlebova, Katarina; Hyzdalova, Martina; Hofmanova, Jirina; Jira, Miroslav; Kysela, Petr; Kozubik, Alois; Kala, Zdenek; Krejci, Pavel

    2012-04-01

    Apoptosis inhibitor 5 (API-5) is a 55 kDa nuclear protein with potent anti-apoptotic signaling in tumor cells in vitro. In this study, we analyzed the expression of the API-5 protein in vivo in a broad spectrum of human carcinomas, including those of the colon, lung, liver, kidney, pancreas, stomach and esophagus using tumor tissues obtained during tumor resection. The results showed significant upregulation of API-5 expression in biopsies of lung (23%, n=13) and colorectal tumors (33%, n=27) in comparison with biopsies from the adjacent normal tissue. Colon cancer biopsies were used to study the cell populations with an upregulated level of expression of API-5 more closely. Using a magnetic bead-based selection for the epithelial cell marker EpCAM, we purified epithelial cells from the tumor and control tissues and analyzed these cells for API-5 expression by western immunoblotting. We observed that EpCAM-positive tumor cells expressed API-5 in all three colorectal cancer cases tested, in contrast to the control EpCAM-positive and EpCAM-negative cells isolated from the control or tumor tissues. These data suggest that the expression of the API-5 protein is upregulated in tumor epithelial cells and may serve as a prognostic marker in colorectal cancer.

  2. Investigation into process-induced de-aggregation of cohesive micronised API particles.

    Science.gov (United States)

    Hoffmann, Magnus; Wray, Patrick S; Gamble, John F; Tobyn, Mike

    2015-09-30

    The aim of this study was to assess the impact of unit processes on the de-aggregation of a cohesive micronised API within a pharmaceutical formulation using near-infrared chemical imaging. The impact on the primary API particles was also investigated using an image-based particle characterization system with integrated Raman analysis. The blended material was shown to contain large, API rich domains which were distributed in-homogeneously across the sample, suggesting that the blending process was not aggressive enough to disperse aggregates of micronised drug particles. Cone milling, routinely used to improve the homogeneity of such cohesive formulations, was observed to substantially reduce the number and size of API rich domains; however, several smaller API domains survived the milling process. Conveyance of the cone milled formulation through the Alexanderwerk WP120 powder feed system completely dispersed all remaining aggregates. Importantly, powder feed transmission of the un-milled formulation was observed to produce an equally homogeneous API distribution. The size of the micronised primary drug particles remained unchanged during powder feed transmission. These findings provide further evidence that this powder feed system does induce shear, and is in fact better able to disperse aggregates of a cohesive micronised API within a blend than the blend-mill-blend step.

  3. Compositional Encounters: Evolvement of Secondary Students' Narratives While Making Historical Desktop Documentaries

    Science.gov (United States)

    Schul, James E.

    2012-01-01

    The increased popularity of desktop documentary making among both teachers and students in history classrooms warrants an examination of its integration into classroom instruction. This multiple case study focused on two secondary students in an AP European History course during a unit that featured desktop documentary making. Employing Cultural…

  4. A Framework for Examining Desktop Video Conferencing in the Organisational Context

    OpenAIRE

    Angelides, Marios C.

    1998-01-01

    This paper proposes, and applies, a framework for examining desktop video conferencing in the organisational context. The framework helps organisations both to uncover the relative benefits of, and problems in, the use of desktop video conferencing and to reconcile some of the problems that evolve from this use.

  5. How do developers use APIs? A case study in concurrency

    NARCIS (Netherlands)

    Blom, Stefan; Kiniry, Joseph; Huisman, Marieke

    2013-01-01

    With the omnipresent usage of APIs in software development, it has become important to analyse how the routines and functionalities of APIs are actually used. This information is in particular useful for API developers, to make decisions about future updates of the API. However, also for developers

  6. Web API Growing Pains: Loosely Coupled yet Strongly Tied

    NARCIS (Netherlands)

    Espinha, T.; Zaidman, A.; Gross, H.G.

    2014-01-01

    Web APIs provide a systematic and extensible approach for application-toapplication interaction. Developers using web APIs are forced to accompany the API providers in their software evolution tasks. In order to understand the distress caused by this imposition on web API client developers we perfor

  7. DySectAPI: Scalable Prescriptive Debugging

    DEFF Research Database (Denmark)

    Jensen, Nicklas Bo; Karlsson, Sven; Quarfot Nielsen, Niklas;

    We present the DySectAPI, a tool that allow users to construct probe trees for automatic, event-driven debugging at scale. The traditional, interactive debugging model, whereby users manually step through and inspect their application, does not scale well even for current supercomputers. While...... lightweight debugging models scale well, they can currently only debug a subset of bug classes. DySectAPI fills the gap between these two approaches with a novel user-guided approach. Using both experimental results and analytical modeling we show how DySectAPI scales and can run with a low overhead...

  8. Laevo: A Temporal Desktop Interface for Integrated Knowledge Work

    DEFF Research Database (Denmark)

    Jeuris, Steven; Houben, Steven; Bardram, Jakob

    2014-01-01

    configuration work to integrate the different tools they use. In order to understand tool usage, we review literature on how users' activities are created and evolve over time as part of knowledge worker practices. From this we derive the activity life cycle, a conceptual framework describing the different......Prior studies show that knowledge work is characterized by highly interlinked practices, including task, file and window management. However, existing personal information management tools primarily focus on a limited subset of knowledge work, forcing users to perform additional manual...... states and transitions of an activity. The life cycle is used to inform the design of Laevo, a temporal activity-centric desktop interface for personal knowledge work. Laevo allows users to structure work within dedicated workspaces, managed on a timeline. Through a centralized notification system which...

  9. GRID : unlimited computing power on your desktop Conference MT17

    CERN Document Server

    2001-01-01

    The Computational GRID is an analogy to the electrical power grid for computing resources. It decouples the provision of computing, data, and networking from its use, it allows large-scale pooling and sharing of resources distributed world-wide. Every computer, from a desktop to a mainframe or supercomputer, can provide computing power or data for the GRID. The final objective is to plug your computer into the wall and have direct access to huge computing resources immediately, just like plugging-in a lamp to get instant light. The GRID will facilitate world-wide scientific collaborations on an unprecedented scale. It will provide transparent access to major distributed resources of computer power, data, information, and collaborations.

  10. Taxonomic characterization of honey bee (Apis mellifera) pollen foraging based on non-overlapping paired-end sequencing of nuclear ribosomal loci

    Science.gov (United States)

    Cornman, Robert S.; Otto, Clint R.; Iwanowicz, Deborah; Pettis, Jeffery S

    2015-01-01

    Identifying plant taxa that honey bees (Apis mellifera) forage upon is of great apicultural interest, but traditional methods are labor intensive and may lack resolution. Here we evaluate a high-throughput genetic barcoding approach to characterize trap-collected pollen from multiple North Dakota apiaries across multiple years. We used the Illumina MiSeq platform to generate sequence scaffolds from non-overlapping 300-bp paired-end sequencing reads of the ribosomal internal transcribed spacers (ITS). Full-length sequence scaffolds represented ~530 bp of ITS sequence after adapter trimming, drawn from the 5’ of ITS1 and the 3’ of ITS2, while skipping the uninformative 5.8S region. Operational taxonomic units (OTUs) were picked from scaffolds clustered at 97% identity, searched by BLAST against the nt database, and given taxonomic assignments using the paired-read lowest common ancestor approach. Taxonomic assignments and quantitative patterns were consistent with known plant distributions, phenology, and observational reports of pollen foraging, but revealed an unexpected contribution from non-crop graminoids and wetland plants. The mean number of plant species assignments per sample was 23.0 (+/- 5.5) and the mean species diversity (effective number of equally abundant species) was 3.3 (+/- 1.2). Bray-Curtis similarities showed good agreement among samples from the same apiary and sampling date. Rarefaction plots indicated that fewer than 50,000 reads are typically needed to characterize pollen samples of this complexity. Our results show that a pre-compiled, curated reference database is not essential for genus-level assignments, but species-level assignments are hindered by database gaps, reference length variation, and probable errors in the taxonomic assignment, requiring post-hoc evaluation. Although the effective per-sample yield achieved using custom MiSeq amplicon primers was less than the machine maximum, primarily due to lower “read2” quality

  11. System Simulation and Optimization of Antenna Layout Based on HFSS-MATLAB-API%基于HFSS-MATLB-API的天线布局优化仿真

    Institute of Scientific and Technical Information of China (English)

    章耀文; 陈少昌

    2015-01-01

    With the increase of the number of antennas applied in the mobile platform, the electromagnetic compatibility problems of cars are becoming more and more serious. According to current situation of antenna layout lacking reasonable model and theoretical method, Matlab is used to control HFSS to generate different models for simulating and optimizing electromagnetic compatibility of the antenna layout by HFSS-Matlab-Api Script library. Using genetic algorithm to optimize layout. This approach can save mathematical model derivation process and reduce the work users repeatedly draw model and modify parameters of duplication. This approach can make full use of the simulation precision, reliability and convenience of HFSS, and using genetic algorithm to reduce the time and cost of blind test. In the end, the experimental results are consistent with the theory, thus verifying the feasibility of layout and optimization method.%随着用于车载平台的天线数量日益增多, 汽车的电磁兼容问题日益严重. 针对天线布局缺少统一合理模型和理论方法指导的现状,利用HFSS-Matlab-Api脚本库在Matlab中调用HFSS建模进行天线布局的电磁兼容性仿真, 采用遗传算法对布局进行优化. 此方法省去人为数学模型推导过程, 减少用户反复绘制模型、修改参数的重复工作. 不仅充分利用HFSS仿真的高精度、可靠性和便捷性, 而且采用遗传算法减少盲目的试探带来的时间和成本的浪费. 最后, 得到与理论相符合的实验结果, 从而验证了布局与优化方法的可行性.

  12. Java Foundation Classes in a Nutshell Desktop Quick Reference

    CERN Document Server

    Flanagan, David

    1999-01-01

    Java Foundation Classes in a Nutshell is an indispensable quick reference for Java programmers who are writing applications that use graphics or graphical user interfaces. The author of the bestsellingJava in a Nutshell has written fast-paced introductions to the Java APIs that comprise the Java Foundation Classes (JFC), such as the Swing GUI components and Java 2D, so that you can start using these exciting new technologies right away. This book also includes O'Reilly's classic-style, quick-reference material for all of the classes in the javax.swing and java.awt packages and their numerous

  13. Real World Uses For Nagios APIs

    Science.gov (United States)

    Singh, Janice

    2014-01-01

    This presentation describes the Nagios 4 APIs and how the NASA Advanced Supercomputing at Ames Research Center is employing them to upgrade its graphical status display (the HUD) and explain why it's worth trying to use them yourselves.

  14. BeXRB Monitor Data API

    Data.gov (United States)

    National Aeronautics and Space Administration — A fully queryable REST API with JSON, XML, and CSV output as well as inline, runable examples. This is a monitor using data from Swift/BAT, MAXI and Fermi/GBM...

  15. ChemSpell Web Service API

    Data.gov (United States)

    U.S. Department of Health & Human Services — The ChemSpell Web Service API provides chemical name spell checking and chemical name synonym look-up. ChemSpell contains more than 1.3 million chemical names...

  16. System for Award Management (SAM) API

    Data.gov (United States)

    General Services Administration — The SAM API is a RESTful method of retrieving public information about the businesses, organizations, or individuals (referred to as entities) within the SAM entity...

  17. Aggressiveness index of Apis Mellifera (Hymenoptera: Aapidae) Índice de agresividad en Apis mellifera ( Hymenoptera: Aapidae )

    OpenAIRE

    Sierra Omar Danilo; Insuasty Torres Jennyfer

    2004-01-01

    An index measuring the aggressiveness among ten colonies of Apis mellifera was elaborated based on the third generation synthetic indices by Charum et al. (1999). The index values are subject to a fixed parameter used as the beginning or standard value, and correspond to the aggressive features of some Africans colonies studied by Rothenbuler et al. (1968). In the ten colonies the index values are notably smaller than those of African colonies and are biased to the lowest values. This indicat...

  18. 基于公开Web Services API的外文图书采访系统的设计与实现%Design and Implementation of Foreign Language Books Collection and Mining System Based on Web Services API

    Institute of Scientific and Technical Information of China (English)

    俞小怡; 刘凡儒; 金玉玲

    2011-01-01

    Using the open Web Services interfaces provided by Rakuten, Google and Amazon, etc., we developed Foreign Books Collection and Mining System based on Web Services API, and supplied a new way of collection and processing in Japanese, English-based multilingual bibliography of foreign language books. Taking Japan Rakuten online mall as an example, we designed the operation processes and policies of online foreign language books collection and mining, and described the working principle and the core technology of metadata mining.%利用乐天、谷歌和亚马逊等知名网站所提供的公开Web Services API接口,可以开发基于WebServices API的外文图书采访系统,提供采集处理以日文、英文为主的多语种外文图书书目信息.文章以日本乐天网上商城提供的API为例,研究基于网上外文图书的采访流程和策略,介绍数据采集转换的工作原理和元数据获取的核心技术.

  19. “Wrapping” X3DOM around Web Audio API

    Directory of Open Access Journals (Sweden)

    Andreas Stamoulias

    2015-12-01

    Full Text Available Spatial sound has a conceptual role in the Web3D environments, due to highly realism scenes that can provide. Lately the efforts are concentrated on the extension of the X3D/ X3DOM through spatial sound attributes. This paper presents a novel method for the introduction of spatial sound components in the X3DOM framework, based on X3D specification and Web Audio API. The proposed method incorporates the introduction of enhanced sound nodes for X3DOM which are derived by the implementation of the X3D standard components, enriched with accessional features of Web Audio API. Moreover, several examples-scenarios developed for the evaluation of our approach. The implemented examples established the achievability of new registered nodes in X3DOM, for spatial sound characteristics in Web3D virtual worlds.

  20. Physicochemical characterisation and investigation of the bonding mechanisms of API-titanate nanotube composites as new drug carrier systems.

    Science.gov (United States)

    Sipos, Barbara; Pintye-Hódi, Klára; Kónya, Zoltán; Kelemen, András; Regdon, Géza; Sovány, Tamás

    2017-02-25

    Titanate nanotube (TNT) has recently been explored as a new carrier material for active pharmaceutical ingredients (API). The aim of the present work was to reveal the physicochemical properties of API-TNT composites, focusing on the interactions between the TNTs and the incorporated APIs. Drugs belonging to different Biopharmaceutical Classification System (BCS) classes were loaded into TNTs: diltiazem hydrochloride (BCS I.), diclofenac sodium (BCS II.), atenolol (BCS III.) and hydrochlorothiazide (BCS IV.). Experimental results demonstrated that it is feasible for spiral cross-sectioned titanate nanotubes to carry drugs and maintain their bioactivity. The structural properties of the composites were characterized by a range of analytical techniques, including FT-IR, DSC, TG-MS, etc. The interactions between APIs and TNTs were identified as electrostatic attractions, mainly dominated by hydrogen bonds. Based on the results, it can be stated that the strength of the association depends on the hydrogen donor strength of the API. The drug release of incorporated APIs was evaluated from compressed tablets and compared to that of pure APIs. Differences noticed in the dissolution profiles due to incorporation showed a correlation with the strength of interactions between the APIs and the TNTs observed in the above analytical studies.

  1. A RESTful API for accessing microbial community data for MG-RAST.

    Science.gov (United States)

    Wilke, Andreas; Bischof, Jared; Harrison, Travis; Brettin, Tom; D'Souza, Mark; Gerlach, Wolfgang; Matthews, Hunter; Paczian, Tobias; Wilkening, Jared; Glass, Elizabeth M; Desai, Narayan; Meyer, Folker

    2015-01-01

    Metagenomic sequencing has produced significant amounts of data in recent years. For example, as of summer 2013, MG-RAST has been used to annotate over 110,000 data sets totaling over 43 Terabases. With metagenomic sequencing finding even wider adoption in the scientific community, the existing web-based analysis tools and infrastructure in MG-RAST provide limited capability for data retrieval and analysis, such as comparative analysis between multiple data sets. Moreover, although the system provides many analysis tools, it is not comprehensive. By opening MG-RAST up via a web services API (application programmers interface) we have greatly expanded access to MG-RAST data, as well as provided a mechanism for the use of third-party analysis tools with MG-RAST data. This RESTful API makes all data and data objects created by the MG-RAST pipeline accessible as JSON objects. As part of the DOE Systems Biology Knowledgebase project (KBase, http://kbase.us) we have implemented a web services API for MG-RAST. This API complements the existing MG-RAST web interface and constitutes the basis of KBase's microbial community capabilities. In addition, the API exposes a comprehensive collection of data to programmers. This API, which uses a RESTful (Representational State Transfer) implementation, is compatible with most programming environments and should be easy to use for end users and third parties. It provides comprehensive access to sequence data, quality control results, annotations, and many other data types. Where feasible, we have used standards to expose data and metadata. Code examples are provided in a number of languages both to show the versatility of the API and to provide a starting point for users. We present an API that exposes the data in MG-RAST for consumption by our users, greatly enhancing the utility of the MG-RAST service.

  2. A RESTful API for accessing microbial community data for MG-RAST.

    Directory of Open Access Journals (Sweden)

    Andreas Wilke

    2015-01-01

    Full Text Available Metagenomic sequencing has produced significant amounts of data in recent years. For example, as of summer 2013, MG-RAST has been used to annotate over 110,000 data sets totaling over 43 Terabases. With metagenomic sequencing finding even wider adoption in the scientific community, the existing web-based analysis tools and infrastructure in MG-RAST provide limited capability for data retrieval and analysis, such as comparative analysis between multiple data sets. Moreover, although the system provides many analysis tools, it is not comprehensive. By opening MG-RAST up via a web services API (application programmers interface we have greatly expanded access to MG-RAST data, as well as provided a mechanism for the use of third-party analysis tools with MG-RAST data. This RESTful API makes all data and data objects created by the MG-RAST pipeline accessible as JSON objects. As part of the DOE Systems Biology Knowledgebase project (KBase, http://kbase.us we have implemented a web services API for MG-RAST. This API complements the existing MG-RAST web interface and constitutes the basis of KBase's microbial community capabilities. In addition, the API exposes a comprehensive collection of data to programmers. This API, which uses a RESTful (Representational State Transfer implementation, is compatible with most programming environments and should be easy to use for end users and third parties. It provides comprehensive access to sequence data, quality control results, annotations, and many other data types. Where feasible, we have used standards to expose data and metadata. Code examples are provided in a number of languages both to show the versatility of the API and to provide a starting point for users. We present an API that exposes the data in MG-RAST for consumption by our users, greatly enhancing the utility of the MG-RAST service.

  3. An analysis of multifractal characteristics of API time series in Nanjing, China

    Science.gov (United States)

    Shen, Chen-hua; Huang, Yi; Yan, Ya-ni

    2016-06-01

    This paper describes multifractal characteristics of daily air pollution index (API) records in Nanjing from 2001 to 2012. The entire daily API time series is first divided into 12 parts that serve as research objects, and the generalized Hurst exponent is calculated for each series. And then, the multifractal sources are analyzed and singularity spectra are shown. Next, based on a singularity spectrum, the multifractal-characteristics parameters (maximum exponent α0, spectrum width Δ α, and asymmetry Δ αas) are introduced. The results show that the fractality of daily API for each year is multifractal. The multifractal sources originate from both a broad probability density function and different long-range correlations with small and large fluctuations. The strength of the distribution multifractality is stronger than that of the correlation multifractality. The variation in the structure of API time series with increasing years is mainly related to long-range correlations. The structure of API time series in some years is richer. These findings can provide a scientific basis for further probing into the complexity of API.

  4. 基于Google Maps API的旅游信息系统设计与实现%Design and Implementation of Tourism Information System Based on Google Maps API

    Institute of Scientific and Technical Information of China (English)

    梁智学

    2013-01-01

    Obtaining more real information of tourism destination is one of most concern for tourists,especially for self-navigation tourists in their tourism planning.This paper proposes a method to construct tourism information system combined Google Maps with Web GIS.Based on J2EE platform,adopting technologies of Struts2 framework,Google Maps API,Ajax,JSON,JQuery and so on,an open travel information platform is implemented.Using the platform,tourists can conveniently obtain more references for their travel planning.%准确获取旅游目的地的各类信息,是广大旅游爱好者,特别是自助游爱好者在旅游规划时最为关心的问题之一.本文提出将Google Maps与Web GIS相结合构建旅游信息系统的方案.基于J2EE平台,综合利用Struts2框架、GoogleMaps API、Ajax、JSON、JQuery等技术,实现一个“网友共建、信息共享”的开放旅游信息系统.该系统的成功实施,能够为广大旅游爱好者进行旅游规划时提供强有力的参考.

  5. APIs and Researchers: The Emperor's New Clothes?

    Directory of Open Access Journals (Sweden)

    Jennifer Edmond

    2015-02-01

    Full Text Available As part of the Europeana Cloud (eCloud project, Trinity College Dublin investigated best practice in the use of web services, such as APIs, for accessing large data sets from cultural heritage collections. This research looked into the provision and use of APIs, and moreover, whether or not more customised programmatic access to datasets is what researchers want or need. In order to understand whether current patterns of API usage reflect a skills gap on the part of researchers or a mismatch of tool to purpose, we looked not only at the creators and developer/users of APIs, but also at humanists already re-using big data; approaches in cultural heritage institutions and other research infrastructures to bring API use to non-technical audiences; and the kinds of training and other support services available or emerging within the data-intensive humanities research lifecycle. We conducted both desk research and a series of 11 interviews with figures working as researchers, developers or data providers, including figures from both the API development and the data usage communities. This research, conducted under the eCloud project and supported by the European Commission’s ICT Policy and Support Programme (Grant number 325091, was begun in March 2014 and is now in its concluding validation stage. The results of the research are not yet finalised, but the contribution is already emerging of this work to the debate about APIs being either the way forward for digital cultural heritage collections, or the Emperor’s New Clothes (or maybe a bit of both.

  6. Comparative Foraging Behavior of Apis Cerana F. and Apis Mellifera L. in Rapeseed under Cage Condition in Chitwan, Nepal

    Directory of Open Access Journals (Sweden)

    Rameshwor Pudasaini

    2014-12-01

    Full Text Available An experiment was conducted to determine the foraging behavior of Apis mellifera L. and Apis cerana F. in rapeseed under cage condition in Chitwan, Nepal during 2012-2013. This experiment showed that Apis cerana F. foraged extra 42 minute per day as compared to Apis mellifera L. Apis cerana F. were more attracted to nectar, whereas Apis mellifera L. were more attracted to pollen collection throughout the day. The activities, in into hives and out from hives, for both species were recorded more at 2:00 pm and least at 8:00 am. The highest in-out were observed at 2:00 pm on both species as Apis mellifera L. 44.33 bees entered into hives and 49.66 bees went out of hives, whereas lower number of Apis cerana F. 43.66 bees entered into hives and 48.16 bees were out of hives. Apis mellifera L. collect 1.22:1 and 0.41:1 pollen nectar ratio at 10:00 am and 4:00 am whereas at same hours Apis cerana collect 1.16:1 and 0.30:1 pollen nectar ratio. Apis cerana F. foraged significantly higher number of rapeseed flowers and plants as compared to Apis mellifera L. under caged condition. It shows that Apis cerana F. was more efficient pollinator as compared to Apis mellifera L. under caged condition.

  7. CALIBRATION, OPTIMIZATION, AND SENSITIVITY AND UNCERTAINTY ALGORITHMS APPLICATION PROGRAMMING INTERFACE (COSU-API)

    Science.gov (United States)

    The Application Programming Interface (API) for Uncertainty Analysis, Sensitivity Analysis, and Parameter Estimation (UA/SA/PE API) tool development, here fore referred to as the Calibration, Optimization, and Sensitivity and Uncertainty Algorithms API (COSU-API), was initially d...

  8. Nielsen PrimeLocation Web/Desktop: Assessing and GIS Mapping Market Area

    Data.gov (United States)

    Social Security Administration — Nielsen PrimeLocation Web and Desktop Software Licensed for Internal Use only: Pop-Facts Demographics Database, Geographic Mapping Data Layers, Geo-Coding locations.

  9. Advanced API security securing APIs with OAuth 2.0, OpenID Connect, JWS, and JWE

    CERN Document Server

    Siriwardena, Prabath

    2014-01-01

    Advanced API Security is a complete reference to the next wave of challenges in enterprise security--securing public and private APIs. API adoption in both consumer and enterprises has gone beyond predictions. It has become the 'coolest' way of exposing business functionalities to the outside world. Both your public and private APIs, need to be protected, monitored and managed. Security is not an afterthought, but API security has evolved a lot in last five years. The growth of standards, out there, has been exponential. That's where AdvancedAPI Security comes in--to wade through the weeds

  10. Acinetobacter apis sp. nov., isolated from the intestinal tract of a honey bee, Apis mellifera.

    Science.gov (United States)

    Kim, Pil Soo; Shin, Na-Ri; Kim, Joon Yong; Yun, Ji-Hyun; Hyun, Dong-Wook; Bae, Jin-Woo

    2014-08-01

    A novel Gram-negative, obligate aerobic, non-motile, and both coccobacillus- and bacillus-shaped bacterium, designated strain HYN18(T), was isolated from the intestinal tract of a honey bee (Apis mellifera). The isolate was oxidase-negative and catalase-positive. Strain HYN18(T) showed optimum growth at 25°C, pH 6-7, and in the presence of 1% (w/v) NaCl in trypticase soy broth medium. The isolate was negative for hydrolyses of starch, casein, gelatin and urea, indole production from tryptone and hemolysis on sheep blood agar. A phylogenetic analysis based on the 16S rRNA gene and rpoB gene sequence showed that strain HYN18(T) was most closely related to Acinetobacter nectaris SAP 763.2(T) and A. boissieri SAP 284.1(T) with 98.3% and 98.1% similarity (16S rRNA gene), respectively, and 84.4% similarity with Acinetobacter nectaris SAP 763.2(T) (rpoB gene). The major cellular fatty acids were summed features 3 (comprising C16:1ω7c /C16:1ω6c ), C12:0 and C16:0. The main isoprenoid quinone was ubiquinone-9 (Q-9). The polar lipids of strain HYN18(T) were phosphatidylethanolamine, three unidentified lipids, an unidentified phospholipid and an unidentified glycolipid. The DNA G+C content was 40.6 mol%. DNA-DNA hybridization experiments indicated less than 33 ± 10% relatedness to the closest phylogenetic species, Acinetobacter nectaris SAP 763.2(T). Thus, the phenotypic, phylogenetic and genotypic analyses indicate that strain HYN18(T) is a novel species within the genus Acinetobacter, for which the name Acinetobacter apis is proposed. The type strain is HYN18(T) (=KACC 16906(T) =JCM 18575(T)).

  11. Fabrication of low cost soft tissue prostheses with the desktop 3D printer

    OpenAIRE

    Yong He; Guang-huai Xue; Jian-zhong Fu

    2014-01-01

    Soft tissue prostheses such as artificial ear, eye and nose are widely used in the maxillofacial rehabilitation. In this report we demonstrate how to fabricate soft prostheses mold with a low cost desktop 3D printer. The fabrication method used is referred to as Scanning Printing Polishing Casting (SPPC). Firstly the anatomy is scanned with a 3D scanner, then a tissue casting mold is designed on computer and printed with a desktop 3D printer. Subsequently, a chemical polishing method is used ...

  12. 基于Flex与Google Earth API的数字流域地图服务平台%Digital Basin Map Service Platform Based on Flex and Google Earth API

    Institute of Scientific and Technical Information of China (English)

    臧英平; 许捍卫; 钱海峰; 葛俊; 仲琳

    2012-01-01

    It is difficult for some department of professional data production and management to acquire other thematic data within the basin such as geographical data, water resources thematic data and so on. As a result, it can not build the application system based the map service. Based on the analysis of Google Earth API and its coordinate system, Flex technology and Google Earth platform are used to establish a simple digital basin map service web platform, which pro vides convenience for the consumers of society to share the Google Geo-Information and enhanced the interactivity of Web application greatly. The platform is applied to design and implement of the hydrological map issuing platform of Taihu Ba sin. Finally, the feasibility of the platform is verified.%对于某些流域内专业数据的生产与管理部门难以获得流域内其他专题数据(如流域地理数据、其他水利专题数据等)导致无法构建以地图服务为基础的流域应用系统的问题,通过对Google Earth API及其坐标系统的分析,采用Flex技术和Google Earth平台构建了一个简易的数字流域地图服务平台,为社会用户共享Google公司的地理数据提供了方便、极大地增强了Web应用程序的互动性和交互能力.将该数字流域地图服务平台应用于太湖流域水情地图发布平台的设计与实现中,验证了该平台的可行性.

  13. Comparative virulence and competition between Nosema apis and Nosema ceranae in honey bees (Apis mellifera).

    Science.gov (United States)

    Milbrath, Meghan O; van Tran, Toan; Huang, Wei-Fong; Solter, Leellen F; Tarpy, David R; Lawrence, Frank; Huang, Zachary Y

    2015-02-01

    Honey bees (Apis mellifera) are infected by two species of microsporidia: Nosema apis and Nosemaceranae. Epidemiological evidence indicates that N. ceranae may be replacing N. apis globally in A. mellifera populations, suggesting a potential competitive advantage of N. ceranae. Mixed infections of the two species occur, and little is known about the interactions among the host and the two pathogens that have allowed N. ceranae to become dominant in most geographical areas. We demonstrated that mixed Nosema species infections negatively affected honey bee survival (median survival=15-17days) more than single species infections (median survival=21days and 20days for N. apis and N. ceranae, respectively), with median survival of control bees of 27days. We found similar rates of infection (percentage of bees with active infections after inoculation) for both species in mixed infections, with N. apis having a slightly higher rate (91% compared to 86% for N. ceranae). We observed slightly higher spore counts in bees infected with N. ceranae than in bees infected with N. apis in single microsporidia infections, especially at the midpoint of infection (day 10). Bees with mixed infections of both species had higher spore counts than bees with single infections, but spore counts in mixed infections were highly variable. We did not see a competitive advantage for N. ceranae in mixed infections; N. apis spore counts were either higher or counts were similar for both species and more N. apis spores were produced in 62% of bees inoculated with equal dosages of the two microsporidian species. N. ceranae does not, therefore, appear to have a strong within-host advantage for either infectivity or spore growth, suggesting that direct competition in these worker bee mid-guts is not responsible for its apparent replacement of N. apis.

  14. Unified Medical Language System Terminology Services (UTS) API

    Data.gov (United States)

    U.S. Department of Health & Human Services — The UTS API is intended for application developers to perform Web service calls and retrieve UMLS data within their own applications. The UTS API provides the...

  15. MODAPS Web Services API for LANCE-MODIS

    Data.gov (United States)

    National Aeronautics and Space Administration — MODAPS Web Services API for LANCE-MODIS. This Application Programming Interface (API) encompasses a library of functions that provides programmatic data access to...

  16. Comparing Speech Recognition Systems (Microsoft API, Google API And CMU Sphinx

    Directory of Open Access Journals (Sweden)

    Veton Këpuska

    2017-03-01

    Full Text Available The idea of this paper is to design a tool that will be used to test and compare commercial speech recognition systems, such as Microsoft Speech API and Google Speech API, with open-source speech recognition systems such as Sphinx-4. The best way to compare automatic speech recognition systems in different environments is by using some audio recordings that were selected from different sources and calculating the word error rate (WER. Although the WER of the three aforementioned systems were acceptable, it was observed that the Google API is superior.

  17. Pro REST API development with nodejs

    CERN Document Server

    Doglio, Fernando

    2015-01-01

    Pro REST API Development with Node.js is your guide to managing and understanding the full capabilities of successful REST development. API design is a hot topic in the programming world, but not many resources exist for developers to really understand how you can leverage the advantages. This book will provide a brief background on REST and the tools it provides (well known and not so well known). Understand how there is more to REST than just JSON and URLs. You will then cover and compare the maintained modules currently available in the npm community, including Express, Restify, Vatican,

  18. Scalable desktop visualisation of very large radio astronomy data cubes

    Science.gov (United States)

    Perkins, Simon; Questiaux, Jacques; Finniss, Stephen; Tyler, Robin; Blyth, Sarah; Kuttel, Michelle M.

    2014-07-01

    Observation data from radio telescopes is typically stored in three (or higher) dimensional data cubes, the resolution, coverage and size of which continues to grow as ever larger radio telescopes come online. The Square Kilometre Array, tabled to be the largest radio telescope in the world, will generate multi-terabyte data cubes - several orders of magnitude larger than the current norm. Despite this imminent data deluge, scalable approaches to file access in Astronomical visualisation software are rare: most current software packages cannot read astronomical data cubes that do not fit into computer system memory, or else provide access only at a serious performance cost. In addition, there is little support for interactive exploration of 3D data. We describe a scalable, hierarchical approach to 3D visualisation of very large spectral data cubes to enable rapid visualisation of large data files on standard desktop hardware. Our hierarchical approach, embodied in the AstroVis prototype, aims to provide a means of viewing large datasets that do not fit into system memory. The focus is on rapid initial response: our system initially rapidly presents a reduced, coarse-grained 3D view of the data cube selected, which is gradually refined. The user may select sub-regions of the cube to be explored in more detail, or extracted for use in applications that do not support large files. We thus shift the focus from data analysis informed by narrow slices of detailed information, to analysis informed by overview information, with details on demand. Our hierarchical solution to the rendering of large data cubes reduces the overall time to complete file reading, provides user feedback during file processing and is memory efficient. This solution does not require high performance computing hardware and can be implemented on any platform supporting the OpenGL rendering library.

  19. Life cycle assessment study of a Chinese desktop personal computer.

    Science.gov (United States)

    Duan, Huabo; Eugster, Martin; Hischier, Roland; Streicher-Porte, Martin; Li, Jinhui

    2009-02-15

    Associated with the tremendous prosperity in world electronic information and telecommunication industry, there continues to be an increasing awareness of the environmental impacts related to the accelerating mass production, electricity use, and waste management of electronic and electric products (e-products). China's importance as both a consumer and supplier of e-products has grown at an unprecedented pace in recent decade. Hence, this paper aims to describe the application of life cycle assessment (LCA) to investigate the environmental performance of Chinese e-products from a global level. A desktop personal computer system has been selected to carry out a detailed and modular LCA which follows the ISO 14040 series. The LCA is constructed by SimaPro software version 7.0 and expressed with the Eco-indicator'99 life cycle impact assessment method. For a sensitivity analysis of the overall LCA results, the so-called CML method is used in order to estimate the influence of the choice of the assessment method on the result. Life cycle inventory information is complied by ecoinvent 1.3 databases, combined with literature and field investigations on the present Chinese situation. The established LCA study shows that that the manufacturing and the use of such devices are of the highest environmental importance. In the manufacturing of such devices, the integrated circuits (ICs) and the Liquid Crystal Display (LCD) are those parts contributing most to the impact. As no other aspects are taken into account during the use phase, the impact is due to the way how the electricity is produced. The final process steps--i.e. the end of life phase--lead to a clear environmental benefit if a formal and modern, up-to-date technical system is assumed, like here in this study.

  20. Cloud desktop virtualization environment Jiangjin power supply company based on electric power engineering management technology research%江津供电公司云桌面虚拟化环境下基于电力工程管理技术探索分析

    Institute of Scientific and Technical Information of China (English)

    郑小发; 杨丽; 龙平平

    2013-01-01

      随着江津供电公司云桌面虚拟化环境下电力网络信息工程工作中的特性是由多个单位工程、工种、平面穿插施工频繁呈现形成影响进度方案完成的要素。为确保平安高效地完成输电电网建设任务,必需认清云桌面虚拟化环境中的电网施工现场的平安管理现状及缺陷,并采取有效的措施进行工程管理。%  With the characteristics of Jiangjin power network information engineering cloud desktop virtualization environment work is composed of a plurality of unit project,types,plane alternate construction frequently present form factors affect the progress plan.To ensure the safe and efficient completion of the transmission grid construction task,essential safety management status and defect recognize the power grid construction site cloud desktop virtualization in the environment,and take effective measures for project management.

  1. 47 CFR 61.46 - Adjustments to the API.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Adjustments to the API. 61.46 Section 61.46... Rules for Dominant Carriers § 61.46 Adjustments to the API. (a) Except as provided in paragraphs (d) and... carrier must calculate an API for each affected basket pursuant to the following methodology: APIt =...

  2. Small Molecule APY606 Displays Extensive Antitumor Activity in Pancreatic Cancer via Impairing Ras-MAPK Signaling

    Science.gov (United States)

    Guo, Na; Liu, Zuojia; Zhao, Wenjing; Wang, Erkang; Wang, Jin

    2016-01-01

    Pancreatic cancer has been found with abnormal expression or mutation in Ras proteins. Oncogenic Ras activation exploits their extensive signaling reach to affect multiple cellular processes, in which the mitogen-activated protein kinase (MAPK) signaling exerts important roles in tumorigenesis. Therapies targeted Ras are thus of major benefit for pancreatic cancer. Although small molecule APY606 has been successfully picked out by virtual drug screening based on Ras target receptor, its in-depth mechanism remains to be elucidated. We herein assessed the antitumor activity of APY606 against human pancreatic cancer Capan-1 and SW1990 cell lines and explored the effect of Ras-MAPK and apoptosis-related signaling pathway on the activity of APY606. APY606 treatment resulted in a dose- and time-dependent inhibition of cancer cell viability. Additionally, APY606 exhibited strong antitumor activity, as evidenced not only by reduction in tumor cell invasion, migration and mitochondrial membrane potential but also by alteration in several apoptotic indexes. Furthermore, APY606 treatment directly inhibited Ras-GTP and the downstream activation of MAPK, which resulted in the down-regulation of anti-apoptotic protein Bcl-2, leading to the up-regulation of mitochondrial apoptosis pathway-related proteins (Bax, cytosolic Cytochrome c and Caspase 3) and of cyclin-dependent kinase 2 and Cyclin A, E. These data suggest that impairing Ras-MAPK signaling is a novel mechanism of action for APY606 during therapeutic intervention in pancreatic cancer. PMID:27223122

  3. Standard methods for Apis mellifera propolis research

    Science.gov (United States)

    Propolis is one of the most fascinating honey bee (Apis mellifera L.) products. It is a plant derived product that bees produce from resins that they collect from different plant organs and with which they mix beeswax. Propolis is a building material and a protective agent in the beehive. It also pl...

  4. The Apis mellifera filamentous virus genome

    Science.gov (United States)

    A complete reference genome of the Apis mellifera Filamentous virus (AmFV) was determined using Illumina Hiseq sequencing. The AmFV genome is a double strand DNA molecule of approximately 498’500 nucleotides with a GC content of 50.8%. It encompasses 251 non overlapping open reading frames (ORFs), e...

  5. DySectAPI: Scalable Prescriptive Debugging

    DEFF Research Database (Denmark)

    Jensen, Nicklas Bo; Karlsson, Sven; Quarfot Nielsen, Niklas;

    We present the DySectAPI, a tool that allow users to construct probe trees for automatic, event-driven debugging at scale. The traditional, interactive debugging model, whereby users manually step through and inspect their application, does not scale well even for current supercomputers. While...

  6. How Do Developers Use APIs? A Case Study in Concurrency

    DEFF Research Database (Denmark)

    Blom, Stefan; Kiniry, Joseph; Huisman, Marieke

    2013-01-01

    With the omnipresent usage of APIs in software development, it has become important to analyse how the routines and functionalities of APIs are actually used. This information is in particular useful for API developers, to make decisions about future updates of the API. However, also for developers...... of static analysis and verification tools this information is highly important, because it indicates where and how to put the most efficient effort in annotating APIs, to make them usable for the static analysis and verification tools. This paper presents an analysis of the usage of the routines...

  7. An Effective Method for Protecting Native API Hook Attacks in User-mode

    Directory of Open Access Journals (Sweden)

    K. Muthumanickam

    2015-01-01

    Full Text Available Today, many modern malware developers is taking the advantage of Application Programming Interface (API hook technique to take the control of the victim computer which making it difficult to detect their presence. Because of the sophistication of rootkit tools, a remote attacker can use native API to compromise any computer which can later be used for many illegal activities such as sniffing network lines, capturing passwords, sending spam and DDoS attack, etc. Thus to protect end-system by identifying and preventing native API malicious code hooking is a challenging problem to the defenders. Today, many different malware-analysis tools incur specific features against malwares but manual and error-prone. In this study, we proposed a behavior-based monitoring detection system to effectively deal native API hooks in user-mode. Unlike other malware identification techniques, our approach involved dynamically analyzing the behavior of native API call hooking malwares. Comparing our experimental evaluation results with existing tools show better performance with no false positive.

  8. OWL应用接口的比较分析%Comparative Analysis of APIs for OWL Ontology

    Institute of Scientific and Technical Information of China (English)

    熊振辉; 于娟

    2015-01-01

    The paper comparatively analyzes three types of APIs for OWL, including Jena API、Protégé API and OWL API, from aspects of characteristics, platforms which they base on, languages which they can process and OWL ontology models. It focuses on commonly-used functions of OWL API and obtains related conclusions: (1) Jena API cannot achieve all functions of OWL because it bases on RDF triple;(2) OWL API is specifically designed for OWL and it supports structural specification of OWL2 which is the latest edition of OWL;(3) current APIs for OWL ontology mostly base on Java platform, whereas APIs base on other platforms (e.g. .net plat-form) have not appeared.%比较分析了Jena API、Protégé API、OWL API这三种OWL应用接口(API)的特点、所基于的平台、可处理的语言以及描述OWL本体的模型,重点介绍了OWL API的常用基本功能,得出了相关结论:(1)Jena API基于RDF三元组的特点使其不能实现OWL语言的全部功能;(2)OWL API针对OWL语言设计,且支持最新的OWL2语言的结构规范;(3)目前这些API都是基于Java平台的,对于其它平台(如.net平台),尚未见有成熟的API出现。

  9. Testing the quality of images for permanent magnet desktop MRI systems using specially designed phantoms.

    Science.gov (United States)

    Qiu, Jianfeng; Wang, Guozhu; Min, Jiao; Wang, Xiaoyan; Wang, Pengcheng

    2013-12-21

    Our aim was to measure the performance of desktop magnetic resonance imaging (MRI) systems using specially designed phantoms, by testing imaging parameters and analysing the imaging quality. We designed multifunction phantoms with diameters of 18 and 60 mm for desktop MRI scanners in accordance with the American Association of Physicists in Medicine (AAPM) report no. 28. We scanned the phantoms with three permanent magnet 0.5 T desktop MRI systems, measured the MRI image parameters, and analysed imaging quality by comparing the data with the AAPM criteria and Chinese national standards. Image parameters included: resonance frequency, high contrast spatial resolution, low contrast object detectability, slice thickness, geometrical distortion, signal-to-noise ratio (SNR), and image uniformity. The image parameters of three desktop MRI machines could be measured using our specially designed phantoms, and most parameters were in line with MRI quality control criterion, including: resonance frequency, high contrast spatial resolution, low contrast object detectability, slice thickness, geometrical distortion, image uniformity and slice position accuracy. However, SNR was significantly lower than in some references. The imaging test and quality control are necessary for desktop MRI systems, and should be performed with the applicable phantom and corresponding standards.

  10. A Comparison of Article Search APIs via Blinded Experiment and Developer Review

    Directory of Open Access Journals (Sweden)

    Jonathan Rochkind

    2013-01-01

    Full Text Available This study looks at perceived user preference between products that can provide a scholarly article search service via an application programming interface (API. The study set up a blinded review and asked users at Johns Hopkins to select the service that provided the most useful results. Few statistically significant preferences were detected, and some interpretation is provided of what the results might tell us. The specific products evaluated for this study are: Serials Solutions Summon, Ex Libris Primo, EBSCO EDS, EBSCOHost ‘traditional’ API, and Elsevier Scopus. Re-usable open source tools for implementing article search were created to support the study and future development, and a developer review of the APIs is included based on the developer's experience in this implementation.

  11. H-Trust:A Group Trust Management System for Peer-to-Peer Desktop Grid

    Institute of Scientific and Technical Information of China (English)

    Huanyu Zhao; Xiaolin Li

    2009-01-01

    Peer-to-Peer Desktop Grid(P2PDG)has emerged as a pervasive cyber-infrastructure tackling many largescale applications with high impacts.As a burgeoning research area,P2PDG can support numerous applications,including scientific computing,file sharing,web services,and virtual organization for collaborative activities and projects.To handle trustworthiness issues of these services.trust and reputation schemes are proposed to establish trust among peers in P2PDG.In this paper,we propose a robust group trust management system,called H-Trust,inspired by the H-index aggregation technique.Leveraging the robustness of the H-index algorithm under incomplete and uncertain circumstances.H-Trust offers a robust personalized reputation evaluation mechanism for both individual and group trusts with minimal communication and computation overheads.We present the H-Trust scheme in five phases,including trust recording,local trust evaluation,trust query phase,spatiai-temporal update phase,and group reputation evaluation phases.The rationale for its design,the analysis of the algorithm are further investigated.To validate the performance of H-Trust scheme.we designed the H-Trust simulator HTrust-Sim to conduct multi-agent-based simulations.Simulation results demonstrate that H-Trust is robust and can identify and isolate malicious peers in large scale systems even when a large portion of peers are malicious.

  12. Low Cost Desktop Image Analysis Workstation With Enhanced Interactive User Interface

    Science.gov (United States)

    Ratib, Osman M.; Huang, H. K.

    1989-05-01

    A multimodality picture archiving and communication system (PACS) is in routine clinical use in the UCLA Radiology Department. Several types workstations are currently implemented for this PACS. Among them, the Apple Macintosh II personal computer was recently chosen to serve as a desktop workstation for display and analysis of radiological images. This personal computer was selected mainly because of its extremely friendly user-interface, its popularity among the academic and medical community and its low cost. In comparison to other microcomputer-based systems the Macintosh II offers the following advantages: the extreme standardization of its user interface, file system and networking, and the availability of a very large variety of commercial software packages. In the current configuration the Macintosh II operates as a stand-alone workstation where images are imported from a centralized PACS server through an Ethernet network using a standard TCP-IP protocol, and stored locally on magnetic disk. The use of high resolution screens (1024x768 pixels x 8bits) offer sufficient performance for image display and analysis. We focused our project on the design and implementation of a variety of image analysis algorithms ranging from automated structure and edge detection to sophisticated dynamic analysis of sequential images. Specific analysis programs were developed for ultrasound images, digitized angiograms, MRI and CT tomographic images and scintigraphic images.

  13. 基于Google map API的Mashup专题地图的设计与制作%Design and production of Mashup thematic maps based on Google map API

    Institute of Scientific and Technical Information of China (English)

    李翔; 丁嘉鹏; 刘鑫夫

    2012-01-01

    Mashup technology,as one of the ten strategic information technologies, has sprang up on the Internet. Introduction is made on the concept and the advantages of map Mashup. Combined with Google map API content, it describes the API thematic map Mashup framework and design concept, and provides an example of making the API thematic map Mashup. Finally it analyzes the opportunities and challenges in the application of the thematic map Mashup.%Mashup技术作为最具有战略意义的十大信息技术之一,正在互联网上逐渐兴起.文中从地图Mashup的概念、优势等方面进行阐述;结合Google map API的内容,描述搭建基于Google map API的Mashup专题地图框架和设计理念,并给出基于Google map API的Mashup专题地图的制作实例,分析Mashup专题地图的具体应用面临的机遇和挑战.

  14. Population Genetics of Nosema apis and Nosema ceranae: One Host (Apis mellifera) and Two Different Histories.

    Science.gov (United States)

    Maside, Xulio; Gómez-Moracho, Tamara; Jara, Laura; Martín-Hernández, Raquel; De la Rúa, Pilar; Higes, Mariano; Bartolomé, Carolina

    2015-01-01

    Two microsporidians are known to infect honey bees: Nosema apis and Nosema ceranae. Whereas population genetics data for the latter have been released in the last few years, such information is still missing for N. apis. Here we analyze the patterns of nucleotide polymorphism at three single-copy loci (PTP2, PTP3 and RPB1) in a collection of Apis mellifera isolates from all over the world, naturally infected either with N. apis (N = 22) or N. ceranae (N = 23), to provide new insights into the genetic diversity, demography and evolution of N. apis, as well as to compare them with evidence from N. ceranae. Neutral variation in N. apis and N. ceranae is of the order of 1%. This amount of diversity suggests that there is no substantial differentiation between the genetic content of the two nuclei present in these parasites, and evidence for genetic recombination provides a putative mechanism for the flow of genetic information between chromosomes. The analysis of the frequency spectrum of neutral variants reveals a significant surplus of low frequency variants, particularly in N. ceranae, and suggests that the populations of the two pathogens are not in mutation-drift equilibrium and that they have experienced a population expansion. Most of the variation in both species occurs within honey bee colonies (between 62%-90% of the total genetic variance), although in N. apis there is evidence for differentiation between parasites isolated from distinct A. mellifera lineages (20%-34% of the total variance), specifically between those collected from lineages A and C (or M). This scenario is consistent with a long-term host-parasite relationship and contrasts with the lack of differentiation observed among host-lineages in N. ceranae (mellifera worldwide population is a recent event.

  15. When is it Biased? Assessing the Representativeness of Twitter's Streaming API

    OpenAIRE

    Morstatter, Fred; Pfeffer, Jürgen; Liu, Huan

    2014-01-01

    Twitter has captured the interest of the scientific community not only for its massive user base and content, but also for its openness in sharing its data. Twitter shares a free 1% sample of its tweets through the "Streaming API", a service that returns a sample of tweets according to a set of parameters set by the researcher. Recently, research has pointed to evidence of bias in the data returned through the Streaming API, raising concern in the integrity of this data service for use in res...

  16. Develop 3G Application with The J2ME SATSA API

    Science.gov (United States)

    JunWu, Xu; JunLing, Liang

    This paper describes research in the use of the Security and Trust Services API for J2ME (SATSA) to develop mobile applications. for 3G networks. SATSA defines a set of APIs that allows J2ME applications to communicate with and access functionality, secure storage and cryptographic operations provided by security elements such as smart cards and Wireless Identification Modules (WIM). A Java Card application could also work as an authentication module in a J2ME-based e-bank application. The e-bank application would allow its users to access their bank accounts using their cell phones.

  17. An overview of the CellML API and its implementation

    Directory of Open Access Journals (Sweden)

    Halstead Matt

    2010-04-01

    Full Text Available Abstract Background CellML is an XML based language for representing mathematical models, in a machine-independent form which is suitable for their exchange between different authors, and for archival in a model repository. Allowing for the exchange and archival of models in a computer readable form is a key strategic goal in bioinformatics, because of the associated improvements in scientific record accuracy, the faster iterative process of scientific development, and the ability to combine models into large integrative models. However, for CellML models to be useful, tools which can process them correctly are needed. Due to some of the more complex features present in CellML models, such as imports, developing code ab initio to correctly process models can be an onerous task. For this reason, there is a clear and pressing need for an application programming interface (API, and a good implementation of that API, upon which tools can base their support for CellML. Results We developed an API which allows the information in CellML models to be retrieved and/or modified. We also developed a series of optional extension APIs, for tasks such as simplifying the handling of connections between variables, dealing with physical units, validating models, and translating models into different procedural languages. We have also provided a Free/Open Source implementation of this application programming interface, optimised to achieve good performance. Conclusions Tools have been developed using the API which are mature enough for widespread use. The API has the potential to accelerate the development of additional tools capable of processing CellML, and ultimately lead to an increased level of sharing of mathematical model descriptions.

  18. Analysis of Desktop Cloud System%桌面云系统浅析

    Institute of Scientific and Technical Information of China (English)

    李春生

    2013-01-01

    As an important developing direction of cloud computing, the desktop cloud system would provide a revolutionary solution for IT management of all sizes of businesses. In this paper, we introduce the desktop cloud system from its architecture, client access methods, security and typical solutions. Users would fully understand the benefits of desktop cloud system.%作为云计算领域一个重要的发展方向,桌面云将会为不同规模的企业提供一种革命性的 IT管理解决方案。本文从体系结构、客户端接入方式、安全性和典型的解决方案四个方面对桌面云进行介绍,让用户充分了解桌面云系统。

  19. From where did the Western honeybee (Apis mellifera) originate?

    Science.gov (United States)

    Han, Fan; Wallberg, Andreas; Webster, Matthew T

    2012-08-01

    The native range of the honeybee Apis mellifera encompasses Europe, Africa, and the Middle East, whereas the nine other species of Apis are found exclusively in Asia. It is therefore commonly assumed that A. mellifera arose in Asia and expanded into Europe and Africa. However, other hypotheses for the origin of A. mellifera have also been proposed based on phylogenetic trees constructed from genetic markers. In particular, an analysis based on >1000 single-nucleotide polymorphism markers placed the root of the tree of A. mellifera subspecies among samples from Africa, suggestive of an out-of-Africa expansion. Here, we re-evaluate the evidence for this and other hypotheses by testing the robustness of the tree topology to different tree-building methods and by removing specimens with a potentially hybrid background. These analyses do not unequivocally place the root of the tree of A. mellifera subspecies within Africa, and are potentially consistent with a variety of hypotheses for honeybee evolution, including an expansion out of Asia. Our analyses also support high divergence between western and eastern European populations of A. mellifera, suggesting they are likely derived from two distinct colonization routes, although the sources of these expansions are still unclear.

  20. Genetic variation in natural honeybee populations, Apis mellifera capensis

    Science.gov (United States)

    Hepburn, Randall; Neumann, Peter; Radloff, Sarah E.

    2004-09-01

    Genetic variation in honeybee, Apis mellifera, populations can be considerably influenced by breeding and commercial introductions, especially in areas with abundant beekeeping. However, in southern Africa apiculture is based on the capture of wild swarms, and queen rearing is virtually absent. Moreover, the introduction of European subspecies constantly failed in the Cape region. We therefore hypothesize a low human impact on genetic variation in populations of Cape honeybees, Apis mellifera capensis. A novel solution to studying genetic variation in honeybee populations based on thelytokous worker reproduction is applied to test this hypothesis. Environmental effects on metrical morphological characters of the phenotype are separated to obtain a genetic residual component. The genetic residuals are then re-calculated as coefficients of genetic variation. Characters measured included hair length on the abdomen, width and length of wax plate, and three wing angles. The data show for the first time that genetic variation in Cape honeybee populations is independent of beekeeping density and probably reflects naturally occurring processes such as gene flow due to topographic and climatic variation on a microscale.

  1. Applications and a Three-dimensional Desktop Environment for an Immersive Virtual Reality System

    CERN Document Server

    Kageyama, Akira

    2013-01-01

    We developed an application launcher called Multiverse for scientific visualizations in a CAVE-type virtual reality (VR) system. Multiverse can be regarded as a type of three-dimensional (3D) desktop environment. In Multiverse, a user in a CAVE room can browse multiple visualization applications with 3D icons and explore movies that float in the air. Touching one of the movies causes "teleportation" into the application's VR space. After analyzing the simulation data using the application, the user can jump back into Multiverse's VR desktop environment in the CAVE.

  2. Asteroids - NeoWs API

    Data.gov (United States)

    National Aeronautics and Space Administration — NeoWs (Near Earth Object Web Service) is a RESTful web service for near earth Asteroid information. With NeoWs a user can: search for Asteroids based on their...

  3. Novel insights into excipient effects on the biopharmaceutics of APIs from different BCS classes: Lactose in solid oral dosage forms.

    Science.gov (United States)

    Kubbinga, Marlies; Moghani, Laura; Langguth, Peter

    2014-09-30

    Excipients encompass a wide range of properties that are of importance for the resulting drug product. Regulatory guidelines on biowaivers for immediate release formulations require an in depth understanding of the biopharmaceutic effects of excipients in order to establish bioequivalence between two different products carrying the same API based on dissolution tests alone. This paper describes a new approach in evaluating biopharmaceutic excipient effects. Actually used quantities of a model excipient, lactose, formulated in combination with APIs from different BCS classes were evaluated. The results suggest that companies use different (relative) amounts depending on the characteristics of the API. The probability of bioinequivalence due to a difference in lactose content between test and reference products was classified as low for BCS class I APIs and medium for BCS class II and III APIs, whereas a high probability was assigned to the combination of lactose and BCS class IV APIs. If repeated for other excipients, this retrospective, top-down approach may lead to a new database and more widespread applications of the biowaiver approach.

  4. APIs for QoS configuration in Software Defined Networks

    DEFF Research Database (Denmark)

    Caba, Cosmin Marius; Soler, José

    2015-01-01

    such as configuration of devices, ports, queues, etc. An Application Programming Interface (API) for dynamic configuration of QoS resources in the network devices is implemented herein, by using the capabilities of OVSDB. Further, the paper demonstrates the possibility to create network services with coarse granularity...... on top of the fine granular services exposed by the QoS configuration API at the SDNC. A series of tests emphasize the capabilities and the performance of the implemented QoS configuration API....

  5. Realization of a Search Website Based on ASP. NET and Yahoo Web APIs%一个基于ASP.NET与Yahoo Web APIs的搜索网站的实现

    Institute of Scientific and Technical Information of China (English)

    刘蓉; 王国顺; 文亮

    2005-01-01

    继Google之后,Yahoo公司也发布了免费和受限的Web搜索服务APIs.本文介绍了Yahoo搜索服务的技术特点,简述了调用接口和返回文档结构,给出了一个基于ASP.NET的搜索网的技术要点和实现代码,设计并实现了一个搜索网实例.

  6. Privacy Issues of the W3C Geolocation API

    CERN Document Server

    Doty, Nick; Wilde, Erik

    2010-01-01

    The W3C's Geolocation API may rapidly standardize the transmission of location information on the Web, but, in dealing with such sensitive information, it also raises serious privacy concerns. We analyze the manner and extent to which the current W3C Geolocation API provides mechanisms to support privacy. We propose a privacy framework for the consideration of location information and use it to evaluate the W3C Geolocation API, both the specification and its use in the wild, and recommend some modifications to the API as a result of our analysis.

  7. Film Pedagogy in the History Classroom: Desktop Documentary-Making Skills for History Teachers and Students

    Science.gov (United States)

    Schul, James E.

    2014-01-01

    The emergence of digital technology provides new opportunities for teaching and learning in the history classroom. However, these new opportunities often require new skills to be learned by teachers and students alike. This article focuses on one such digitally oriented strategy, desktop documentary making, which empowers students to easily make…

  8. Negotiation of Meaning in Desktop Videoconferencing-Supported Distance Language Learning

    Science.gov (United States)

    Wang, Yuping

    2006-01-01

    The aim of this research is to reveal the dynamics of focus on form in task completion via videoconferencing. This examination draws on current second language learning theories regarding effective language acquisition, research in Computer Mediated Communication (CMC) and empirical data from an evaluation of desktop videoconferencing-supported…

  9. Free Molecular Heat Transfer Programs for Setup and Dynamic Updating the Conductors in Thermal Desktop

    Science.gov (United States)

    Malroy, Eric T.

    2007-01-01

    The programs, arrays and logic structure were developed to enable the dynamic update of conductors in thermal desktop. The MatLab program FMHTPRE.m processes the Thermal Desktop conductors and sets up the arrays. The user needs to manually copy portions of the output to different input regions in Thermal Desktop. Also, Fortran subroutines are provided that perform the actual updates to the conductors. The subroutines are setup for helium gas, but the equations can be modified for other gases. The maximum number of free molecular conductors allowed is 10,000 for a given radiation task. Additional radiation tasks for FMHT can be generated to account for more conductors. Modifications to the Fortran subroutines may be warranted, when the mode of heat transfer is in the mixed or continuum mode. The FMHT Thermal Desktop model should be activated by using the "Case Set Manager" once the model is setup. Careful setup of the model is needed to avoid excessive solve times.

  10. Generating Alternative Engineering Designs by Integrating Desktop VR with Genetic Algorithms

    Science.gov (United States)

    Chandramouli, Magesh; Bertoline, Gary; Connolly, Patrick

    2009-01-01

    This study proposes an innovative solution to the problem of multiobjective engineering design optimization by integrating desktop VR with genetic computing. Although, this study considers the case of construction design as an example to illustrate the framework, this method can very much be extended to other engineering design problems as well.…

  11. Use of Signaling to Integrate Desktop Virtual Reality and Online Learning Management Systems

    Science.gov (United States)

    Dodd, Bucky J.; Antonenko, Pavlo D.

    2012-01-01

    Desktop virtual reality is an emerging educational technology that offers many potential benefits for learners in online learning contexts; however, a limited body of research is available that connects current multimedia learning techniques with these new forms of media. Because most formal online learning is delivered using learning management…

  12. Computing on the Desktop: From Batch to Online in Two Large Danish Service Bureaus

    DEFF Research Database (Denmark)

    Jørgensen, Anker Helms

    The advent of the personal computer is often hailed as the major step towards empowering the computer user. This step was indeed significant, but it was preceeded by a similar step some 10-15 years earlier: the advent of the video terminal or ”glass–TTY”. The video terminal invaded the desktop...

  13. Students' Beliefs about Mobile Devices vs. Desktop Computers in South Korea and the United States

    Science.gov (United States)

    Sung, Eunmo; Mayer, Richard E.

    2012-01-01

    College students in the United States and in South Korea completed a 28-item multidimensional scaling (MDS) questionnaire in which they rated the similarity of 28 pairs of multimedia learning materials on a 10-point scale (e.g., narrated animation on a mobile device Vs. movie clip on a desktop computer) and a 56-item semantic differential…

  14. User satisfaction survey and usage of an electronic desktop document delivery service at an academic medical library.

    Science.gov (United States)

    Sayed, Ellen N; Murray, Sarah D

    2003-01-01

    In June 2000, the Biomedical Library at the University of South Alabama introduced Prospero, an electronic desktop document delivery service. From June 2000 to November 2002, Prospero delivered 28% of interlibrary loan requests and 72% of document delivery requests. In November 2002, the library conducted a user satisfaction survey of the Prospero service. Forty-two surveys were used. Fifteen responses were received from affiliated faculty, staff, and students, who generally expressed satisfaction with the service. Twenty-seven responses were received from unaffiliated users, comprised of medical libraries, individual users, and businesses. Based on the survey results, the library deemed the Prospero service a success. To better support users, the library's Web page was updated to include hardware and software requirements for successful use of the Prospero service, as well as screen shots of the Prospero process.

  15. Auto-ubiquitination-induced degradation of MALT1-API2 prevents BCL10 destabilization in t(11;18(q21;q21-positive MALT lymphoma.

    Directory of Open Access Journals (Sweden)

    Heidi Noels

    Full Text Available BACKGROUND: The translocation t(11;18(q21;q21 is the most frequent chromosomal aberration associated with MALT lymphoma and results in constitutive NF-kappaB activity via the expression of an API2-MALT1 fusion protein. The properties of the reciprocal MALT1-API2 were never investigated as it was reported to be rarely transcribed. PRINCIPAL FINDINGS: Our data indicate the presence of MALT1-API2 transcripts in the majority of t(11;18(q21;q21-positive MALT lymphomas. Based on the breakpoints in the MALT1 and API2 gene, the MALT1-API2 protein contains the death domain and one or both immunoglobulin-like domains of MALT1 (approximately 90% of cases--mediating the possible interaction with BCL10--fused to the RING domain of API2. Here we show that this RING domain enables MALT1-API2 to function as an E3 ubiquitin ligase for BCL10, inducing its ubiquitination and proteasomal degradation in vitro. Expression of MALT1-API2 transcripts in t(11;18(q21;q21-positive MALT lymphomas was however not associated with a reduction of BCL10 protein levels. CONCLUSION: As we observed MALT1-API2 to be an efficient target of its own E3 ubiquitin ligase activity, our data suggest that this inherent instability of MALT1-API2 prevents its accumulation and renders a potential effect on MALT lymphoma development via destabilization of BCL10 unlikely.

  16. API, Cloud computing, WebGIS and cartography

    Directory of Open Access Journals (Sweden)

    Andrea Favretto

    2013-05-01

    Full Text Available This paper explores some of the digital mapping processes available on the Internet in order to analyse their cartographic congruence. It will focus on WebGIS-based cartography in relation to what is produced using Mash-up site maps. These websites often use Googlebased maps in order to produce their own cartography. Thus, we can identify two main typologies of Internet mapping sites, which are characterized by the ownership or non-ownership of their cartographic bases. This paper will critically assess the cartography employed in the two different instances. A concise introduction to the Cloud Computing Internet propagated phenomenon is also premised in order to provide the reader with an accurate frame of reference. Cloud Computing has encouraged a significant Internet participation via the Application Programming Interface software (API, leading to mash-up cartographic websites.

  17. Characterization of emissions from a desktop 3D printer and indoor air measurements in office settings.

    Science.gov (United States)

    Steinle, Patrick

    2016-01-01

    Emissions from a desktop 3D printer based on fused deposition modeling (FDM) technology were measured in a test chamber and indoor air was monitored in office settings. Ultrafine aerosol (UFA) emissions were higher while printing a standard object with polylactic acid (PLA) than with acrylonitrile butadiene styrene (ABS) polymer (2.1 × 10(9) vs. 2.4 × 10(8) particles/min). Prolonged use of the printer led to higher emission rates (factor 2 with PLA and 4 with ABS, measured after seven months of occasional use). UFA consisted mainly of volatile droplets, and some small (100-300 nm diameter) iron containing and soot-like particles were found. Emissions of inhalable and respirable dust were below the limit of detection (LOD) when measured gravimetrically, and only slightly higher than background when measured with an aerosol spectrometer. Emissions of volatile organic compounds (VOC) were in the range of 10 µg/min. Styrene accounted for more than 50% of total VOC emitted when printing with ABS; for PLA, methyl methacrylate (MMA, 37% of TVOC) was detected as the predominant compound. Two polycyclic aromatic hydrocarbons (PAH), fluoranthene and pyrene, were observed in very low amounts. All other analyzed PAH, as well as inorganic gases and metal emissions except iron (Fe) and zinc (Zn), were below the LOD or did not differ from background without printing. A single 3D print (165 min) in a large, well-ventilated office did not significantly increase the UFA and VOC concentrations, whereas these were readily detectable in a small, unventilated room, with UFA concentrations increasing by 2,000 particles/cm(3) and MMA reaching a peak of 21 µg/m(3) and still being detectable in the room even 20 hr after printing.

  18. Rare royal families in honeybees, Apis mellifera

    Science.gov (United States)

    Moritz, Robin F. A.; Lattorff, H. Michael G.; Neumann, Peter; Kraus, F. Bernhard; Radloff, Sarah E.; Hepburn, H. Randall

    2005-10-01

    The queen is the dominant female in the honeybee colony, Apis mellifera, and controls reproduction. Queen larvae are selected by the workers and are fed a special diet (royal jelly), which determines caste. Because queens mate with many males a large number of subfamilies coexist in the colony. As a consequence, there is a considerable potential for conflict among the subfamilies over queen rearing. Here we show that honeybee queens are not reared at random but are preferentially reared from rare “royal” subfamilies, which have extremely low frequencies in the colony's worker force but a high frequency in the queens reared.

  19. ApiNATOMY: a novel toolkit for visualizing multiscale anatomy schematics with phenotype-related information.

    Science.gov (United States)

    de Bono, Bernard; Grenon, Pierre; Sammut, Stephen John

    2012-05-01

    A significant proportion of biomedical resources carries information that cross references to anatomical structures across multiple scales. To improve the visualization of such resources in their anatomical context, we developed an automated methodology that produces anatomy schematics in a consistent manner,and provides for the overlay of anatomy-related resource information onto the same diagram. This methodology, called ApiNATOMY, draws upon the topology of ontology graphs to automatically lay out treemaps representing body parts as well as semantic metadata linking to such ontologies. More generally, ApiNATOMY treemaps provide an efficient and manageable way to visualize large biomedical ontologies in a meaningful and consistent manner. In the anatomy domain, such treemaps will allow epidemiologists, clinicians, and biomedical scientists to review, and interact with, anatomically aggregated heterogeneous data and model resources. Such an approach supports the visual identification of functional relations between anatomically colocalized resources that may not be immediately amenable to automation by ontology-based inferencing. We also describe the application of ApiNATOMY schematics to integrate, and add value to, human phenotype-related information—results are found at http://apinatomy.org. The long-term goal for the ApiNATOMY toolkit is to support clinical and scientific graphical user interfaces and dashboards for biomedical resource management and data analytics.

  20. Enabling Mobile Air Quality App Development with an AirNow API

    Science.gov (United States)

    Dye, T.; White, J. E.; Ludewig, S. A.; Dickerson, P.; Healy, A. N.; West, J. W.; Prince, L. A.

    2013-12-01

    The U.S. Environmental Protection Agency's (EPA) AirNow program works with over 130 participating state, local, and federal air quality agencies to obtain, quality control, and store real-time air quality observations and forecasts. From these data, the AirNow system generates thousands of maps and products each hour. Each day, information from AirNow is published online and in other media to assist the public in making health-based decisions related to air quality. However, an increasing number of people use mobile devices as their primary tool for obtaining information, and AirNow has responded to this trend by publishing an easy-to-use Web API that is useful for mobile app developers. This presentation will describe the various features of the AirNow application programming interface (API), including Representational State Transfer (REST)-type web services, file outputs, and RSS feeds. In addition, a web portal for the AirNow API will be shown, including documentation on use of the system, a query tool for configuring and running web services, and general information about the air quality data and forecasts available. Data published via the AirNow API includes corresponding Air Quality Index (AQI) levels for each pollutant. We will highlight examples of mobile apps that are using the AirNow API to provide location-based, real-time air quality information. Examples will include mobile apps developed for Minnesota ('Minnesota Air') and Washington, D.C. ('Clean Air Partners Air Quality'), and an app developed by EPA ('EPA AirNow').

  1. grlc Makes GitHub Taste Like Linked Data APIs

    NARCIS (Netherlands)

    Meroño-Peñuela, A.; Hoekstra, Rinke; Sack, H; Rizzo, G; Steinmetz, N; Mladenić, D; Auer, S; Lange, C

    2016-01-01

    Building Web APIs on top of SPARQL endpoints is becoming a common practice to enable universal access to the integration favorable dataspace of Linked Data. However, the Linked Data community cannot expect users to learn SPARQL to query this dataspace, and Web APIs are the most extended way of enabl

  2. API and CPTDC Jointly Promote Chinese Enterprises to Go Abroad

    Institute of Scientific and Technical Information of China (English)

    Li Chunhui

    2005-01-01

    @@ In order to push the certification forward and help more Chinese enterprises to go abroad, API (American Petroleum Institute) and CPTDC (China Petroleum Technology & Development Corporation) jointly held a meeting between March 4 and 8, 2004, to promote API certification of Chinese enterprises.

  3. Interfacing RASCAL with Java APIs. Automated mapping with Apache POI

    NARCIS (Netherlands)

    Marmanidis, G.

    2013-01-01

    Interfacing RASCAL with Java APIs and reusing existing implementations is a required functionality in order to reduce effort and time in contrast with implementing a new one from scratch. In this study we are trying to interface RASCAL with Apache POI, a Java implemented API in order to import and a

  4. Experience API: Flexible, Decentralized and Activity-Centric Data Collection

    Science.gov (United States)

    Kevan, Jonathan M.; Ryan, Paul R.

    2016-01-01

    This emerging technology report describes the Experience API (xAPI), a new e-learning specification designed to support the learning community in standardizing and collecting both formal and informal distributed learning activities. Informed by Activity Theory, a framework aligned with constructivism, data is collected in the form of activity…

  5. Investigating an API for resilient exascale computing.

    Energy Technology Data Exchange (ETDEWEB)

    Stearley, Jon R.; Tomkins, James; VanDyke, John P.; Ferreira, Kurt Brian; Laros, James H.,; Bridges, Patrick

    2013-05-01

    Increased HPC capability comes with increased complexity, part counts, and fault occurrences. In- creasing the resilience of systems and applications to faults is a critical requirement facing the viability of exascale systems, as the overhead of traditional checkpoint/restart is projected to outweigh its bene ts due to fault rates outpacing I/O bandwidths. As faults occur and propagate throughout hardware and software layers, pervasive noti cation and handling mechanisms are necessary. This report describes an initial investigation of fault types and programming interfaces to mitigate them. Proof-of-concept APIs are presented for the frequent and important cases of memory errors and node failures, and a strategy proposed for lesystem failures. These involve changes to the operating system, runtime, I/O library, and application layers. While a single API for fault handling among hardware and OS and application system-wide remains elusive, the e ort increased our understanding of both the mountainous challenges and the promising trailheads. 3

  6. 基于PSS/E潮流API接口的动态过程仿真系统%Dynamic process simulation system based on power flow API of PSS/E

    Institute of Scientific and Technical Information of China (English)

    王勇; 李峰; 潘玲玲; 刘俊; 徐鹏

    2014-01-01

    电力系统仿真分析软件PSS/E提供了丰富的API接口,为应用程序的二次开发提供了便利。基于PSS/E的Fortran API接口设计实现了以PSS/E潮流计算为核心的动态过程仿真系统。通过对API接口的二次开发和封装,建立潮流计算接口层,实现对PSS/E潮流计算的控制。建立了用户自定义调速器模型,将频率和调速器仿真结果通过接口层与PSS/E潮流进行交互,实现系统的动态响应过程仿真。通过潮流计算前的不平衡功率动态预分配技术,使扰动过程中联络线功率分配更加真实合理。通过9节点算例和华北实际电网模型对仿真系统进行验证,仿真结果表明,利用PSS/E的API接口进行二次开发能够满足大型应用程序对准确性和实时性的要求。%Power system simulation software PSS/E provides many interfaces to develop the application program. The dynamic process simulation system, with PSS/E power flow calculation as the core, is designed by Fortran API interface. First, the power flow calculation interface layer is achieved via API secondary developing and encapsulation to control the PSS/E power flow. Then a user-defined governor model is established, and frequency and governor simulation results interact with PSS/E power flow through the interface layer to achieve the dynamic process simulation. Dynamic predistribution technology of unbalance power during the simulation process is proposed, which makes the distribution of tie line power flow more reasonable during disturbance. Finally, the simulation results of IEEE 9-buses system and North China Power Grid verify that secondary development by PSS/E API interface can satisfy the requirements of real-time and high accuracy of large applications.

  7. Coming 5th Edition of the API Standard 618: major changes compared to the API 618, 4th edition

    NARCIS (Netherlands)

    Pyle, A.; Eijk, A.; Elferink, H.

    2003-01-01

    This paper will present the highlights of changes that will be found in the 5th Edition of API 618, which is expected to be published in late 2003 or early 2004. Approximately every 5 years the API Standards are revised in such a way that the latest field experiences and proven designs are included

  8. A Five-Year Hedonic Price Breakdown for Desktop Personal Computer Attributes in Brazil

    Directory of Open Access Journals (Sweden)

    Nuno Manoel Martins Dias Fouto

    2009-07-01

    Full Text Available The purpose of this article is to identify the attributes that discriminate the prices of personal desktop computers. We employ the hedonic price method in evaluating such characteristics. This approach allows market prices to be expressed as a function, a set of attributes present in the products and services offered. Prices and characteristics of up to 3,779 desktop personal computers offered in the IT pages of one of the main Brazilian newspapers were collected from January 2003 to December 2007. Several specifications for the hedonic (multivariate linear regression were tested. In this particular study, the main attributes were found to be hard drive capacity, screen technology, main board brand, random memory size, microprocessor brand, video board memory, digital video and compact disk recording devices, screen size and microprocessor speed. These results highlight the novel contribution of this study: the manner and means in which hedonic price indexes may be estimated in Brazil.

  9. Student Use of Library Computers: Are Desktop Computers Still Relevant in Today's Libraries?

    Directory of Open Access Journals (Sweden)

    Susan Thompson

    2012-12-01

    Full Text Available Academic libraries have traditionally provided computers for students to access their collections and, more recently, facilitate all aspects of studying. Recent changes in technology, particularly the increased presence of mobile devices, calls into question how libraries can best provide technology support and how it might impact the use of other library services. A two-year study conducted at California State University San Marcos library analyzed student use of the computers in the library, both the library’s own desktop computers and laptops owned by students.  The results found that, despite the increased ownership of mobile technology by students, they still clearly preferred to use desktop computers in the library. It also showed that students who used computers in the library were more likely to use other library services and physical collections.

  10. Real-time Desktop Flying Qualities Evaluation Simulator

    Directory of Open Access Journals (Sweden)

    Kamali C.

    2014-01-01

    Full Text Available This paper presents the application of model based design for the development of a real-time flying quality evaluation simulator named NALSim, built around Windows platform. NALSim is a novel rapid prototyping system based on MatlabR, SimulinkR and the Real-Time-Windows TargetR, applicable for fighter, transport and unmanned air vehicles/micro air vehicles simulations. The simulator uses state of the art modeling and simulation technologies to validate various design and flying quality concepts. NALSim is developed such that it is scalable and low cost. The paper presents the simulator architecture and its application for flying qualities. A novel non linear Least Squares optimization based methodology is proposed for efficient handling quality studies.Defence Science Journal, Vol. 64, No. 1, January 2014, DOI:10.14429/dsj.64.4961

  11. Reducing the Digital Divide among Children Who Received Desktop or Hybrid Computers for the Home

    Directory of Open Access Journals (Sweden)

    Gila Cohen Zilka

    2016-06-01

    Full Text Available Researchers and policy makers have been exploring ways to reduce the digital divide. Parameters commonly used to examine the digital divide worldwide, as well as in this study, are: (a the digital divide in the accessibility and mobility of the ICT infrastructure and of the content infrastructure (e.g., sites used in school; and (b the digital divide in literacy skills. In the present study we examined the degree of effectiveness of receiving a desktop or hybrid computer for the home in reducing the digital divide among children of low socio-economic status aged 8-12 from various localities across Israel. The sample consisted of 1,248 respondents assessed in two measurements. As part of the mixed-method study, 128 children were also interviewed. Findings indicate that after the children received desktop or hybrid computers, changes occurred in their frequency of access, mobility, and computer literacy. Differences were found between the groups: hybrid computers reduce disparities and promote work with the computer and surfing the Internet more than do desktop computers. Narrowing the digital divide for this age group has many implications for the acquisition of skills and study habits, and consequently, for the realization of individual potential. The children spoke about self improvement as a result of exposure to the digital environment, about a sense of empowerment and of improvement in their advantage in the social fabric. Many children expressed a desire to continue their education and expand their knowledge of computer applications, the use of software, of games, and more. Therefore, if there is no computer in the home and it is necessary to decide between a desktop and a hybrid computer, a hybrid computer is preferable.

  12. Fab the coming revolution on your desktop : from personal computers to personal fabrication

    CERN Document Server

    Gershenfeld, Neil

    2005-01-01

    What if you could someday put the manufacturing power of an automobile plant on your desktop? According to Neil Gershenfeld, the renowned MIT scientist and inventor, the next big thing is personal fabrication-the ability to design and produce your own products, in your own home, with a machine that combines consumer electronics and industrial tools. Personal fabricators are about to revolutionize the world just as personal computers did a generation ago, and Fab shows us how.

  13. Desktop system for accounting, audit, and research in A&E.

    Science.gov (United States)

    Taylor, C J; Brain, S G; Bull, F; Crosby, A C; Ferguson, D G

    1997-03-01

    The development of a database for audit, research, and accounting in accident and emergency (A&E) is described. The system uses a desktop computer, an optical scanner, sophisticated optical mark reader software, and workload management data. The system is highly flexible, easy to use, and at a cost of around 16,000 pounds affordable for larger departments wishing to move towards accounting. For smaller departments, it may be an alternative to full computerisation.

  14. Comparison of learning and memory of Apis cerana and Apis mellifera.

    Science.gov (United States)

    Qin, Qiu-Hong; He, Xu-Jiang; Tian, Liu-Qing; Zhang, Shao-Wu; Zeng, Zhi-Jiang

    2012-10-01

    The honeybee is an excellent model organism for research on learning and memory among invertebrates. Learning and memory in honeybees has intrigued neuroscientists and entomologists in the last few decades, but attention has focused almost solely on the Western honeybee, Apis mellifera. In contrast, there have been few studies on learning and memory in the Eastern honeybee, Apis cerana. Here we report comparative behavioral data of color and grating learning and memory for A. cerana and A. mellifera in China, gathered using a Y-maze apparatus. We show for the first time that the learning and memory performance of A. cerana is significantly better on both color and grating patterns than that of A. mellifera. This study provides the first evidence of a learning and memory difference between A. cerana and A. mellifera under controlled conditions, and it is an important basis for the further study of the mechanism of learning and memory in honeybees.

  15. Learning Computer Hardware by Doing: Are Tablets Better than Desktops?

    Science.gov (United States)

    Raven, John; Qalawee, Mohamed; Atroshi, Hanar

    2016-01-01

    In this world of rapidly evolving technologies, educational institutions often struggle to keep up with change. Change often requires a state of readiness at both the micro and macro levels. This paper looks at a tertiary institution that undertook a significant technology change initiative by introducing tablet based components for teaching a…

  16. Investigation Methodology of a Virtual Desktop Infrastructure for IoT

    Directory of Open Access Journals (Sweden)

    Doowon Jeong

    2015-01-01

    Full Text Available Cloud computing for IoT (Internet of Things has exhibited the greatest growth in the IT market in the recent past and this trend is expected to continue. Many companies are adopting a virtual desktop infrastructure (VDI for private cloud computing to reduce costs and enhance the efficiency of their servers. As a VDI is widely used, threats of cyber terror and invasion are also increasing. To minimize the damage, response procedure for cyber intrusion on a VDI should be systematized. Therefore, we propose an investigation methodology for VDI solutions in this paper. Here we focus on a virtual desktop infrastructure and introduce various desktop virtualization solutions that are widely used, such as VMware, Citrix, and Microsoft. In addition, we verify the integrity of the data acquired in order that the result of our proposed methodology is acceptable as evidence in a court of law. During the experiment, we observed an error: one of the commonly used digital forensic tools failed to mount a dynamically allocated virtual disk properly.

  17. Compositional mining of multiple object API protocols through state abstraction.

    Science.gov (United States)

    Dai, Ziying; Mao, Xiaoguang; Lei, Yan; Qi, Yuhua; Wang, Rui; Gu, Bin

    2013-01-01

    API protocols specify correct sequences of method invocations. Despite their usefulness, API protocols are often unavailable in practice because writing them is cumbersome and error prone. Multiple object API protocols are more expressive than single object API protocols. However, the huge number of objects of typical object-oriented programs poses a major challenge to the automatic mining of multiple object API protocols: besides maintaining scalability, it is important to capture various object interactions. Current approaches utilize various heuristics to focus on small sets of methods. In this paper, we present a general, scalable, multiple object API protocols mining approach that can capture all object interactions. Our approach uses abstract field values to label object states during the mining process. We first mine single object typestates as finite state automata whose transitions are annotated with states of interacting objects before and after the execution of the corresponding method and then construct multiple object API protocols by composing these annotated single object typestates. We implement our approach for Java and evaluate it through a series of experiments.

  18. The pheromones of laying workers in two honeybee sister species: Apis cerana and Apis mellifera.

    Science.gov (United States)

    Tan, Ken; Yang, Mingxian; Wang, Zhengwei; Radloff, Sarah E; Pirk, Christian W W

    2012-04-01

    When a honeybee colony loses its queen, workers activate their ovaries and begin to lay eggs. This is accompanied by a shift in their pheromonal bouquet, which becomes more queen like. Workers of the Asian hive bee Apis cerana show unusually high levels of ovary activation and this can be interpreted as evidence for a recent evolutionary arms race between queens and workers over worker reproduction in this species. To further explore this, we compared the rate of pheromonal bouquet change between two honeybee sister species of Apis cerana and Apis mellifera under queenright and queenless conditions. We show that in both species, the pheromonal components HOB, 9-ODA, HVA, 9-HDA, 10-HDAA and 10-HDA have significantly higher amounts in laying workers than in non-laying workers. In the queenright colonies of A. mellifera and A. cerana, the ratios (9-ODA)/(9-ODA + 9-HDA + 10-HDAA + 10-HDA) are not significantly different between the two species, but in queenless A. cerana colonies the ratio is significant higher than in A. mellifera, suggesting that in A. cerana, the workers' pheromonal bouquet is dominated by the queen compound, 9-ODA. The amount of 9-ODA in laying A. cerana workers increased by over 585% compared with the non-laying workers, that is 6.75 times higher than in A. mellifera where laying workers only had 86% more 9-ODA compared with non-laying workers.

  19. Femtogram detection of horseradish peroxidase by a common desktop scanner.

    Science.gov (United States)

    Parween, Shahila; Nahar, Pradip

    2015-01-01

    We report an image-based detection of horseradish peroxidase (HRP) by different color spaces. The results show excellent correlation between color saturation and absorbance (Pearson correlation coefficient; 0.9868) with respect to HRP. The present method can detect 185 and 46.45 fg/ml of HRP using o-phenylenediamine dihydrochloride and 3,3',5,5'-tetramethylbenzidine as chromogenic substrates respectively.

  20. No effect of ambient odor on the affective appraisal of a desktop virtual environment with signs of disorder.

    Directory of Open Access Journals (Sweden)

    Alexander Toet

    Full Text Available BACKGROUND: Desktop virtual environments (VEs are increasingly deployed to study the effects of environmental qualities and interventions on human behavior and safety related concerns in built environments. For these applications it is essential that users appraise the affective qualities of the VE similar to those of its real world counterpart. Previous studies have shown that factors like simulated lighting, sound and dynamic elements all contribute to the affective appraisal of a desktop VE. Since ambient odor is known to affect the affective appraisal of real environments, and has been shown to increase the sense of presence in immersive VEs, it may also be an effective tool to tune the affective appraisal of desktop VEs. This study investigated if exposure to ambient odor can modulate the affective appraisal of a desktop VE with signs of public disorder. METHOD: Participants explored a desktop VE representing a suburban neighborhood with signs of public disorder (neglect, vandalism and crime, while being exposed to either room air or subliminal levels of unpleasant (tar or pleasant (cut grass ambient odor. Whenever they encountered signs of disorder they reported their safety related concerns and associated affective feelings. RESULTS: Signs of crime in the desktop VE were associated with negative affective feelings and concerns for personal safety and personal property. However, there was no significant difference between reported safety related concerns and affective connotations in the control (no-odor and in each of the two ambient odor conditions. CONCLUSION: Ambient odor did not affect safety related concerns and affective connotations associated with signs of disorder in the desktop VE. Thus, semantic congruency between ambient odor and a desktop VE may not be sufficient to influence its affective appraisal, and a more realistic simulation in which simulated objects appear to emit scents may be required to achieve this goal.

  1. A framework for API solubility modelling

    DEFF Research Database (Denmark)

    Conte, Elisa; Gani, Rafiqul; Crafts, Peter

    The solubility of solid organic compounds in water and organic solvents is a fundamental thermodynamic property for many purposes such as product-process design and optimization, for the chemical and pharmaceutical industry. Experimental literature solubility data are usually scarce and temperature......-dependent measurements are expensive in terms of time and resources. The few available data are badly organized and difficult to use for fast solubility calculations and solvent screening. Available models often require time consuming and complex implementation together with a good user expertise for their efficient use....... In addition, most of the models are not predictive and requires experimental data for the calculation of the needed parameters. This work aims at developing an efficient framework for the solubility modelling of Active Pharmaceutical Ingredients (API) in water and organic solvents. With this framework...

  2. Surface acidity and solid-state compatibility of excipients with an acid-sensitive API: case study of atorvastatin calcium.

    Science.gov (United States)

    Govindarajan, Ramprakash; Landis, Margaret; Hancock, Bruno; Gatlin, Larry A; Suryanarayanan, Raj; Shalaev, Evgenyi Y

    2015-04-01

    The objectives of this study were to measure the apparent surface acidity of common excipients and to correlate the acidity with the chemical stability of an acid-sensitive active pharmaceutical ingredient (API) in binary API-excipient powder mixtures. The acidity of 26 solid excipients was determined by two methods, (i) by measuring the pH of their suspensions or solutions and (ii) the pH equivalent (pHeq) measured via ionization of probe molecules deposited on the surface of the excipients. The chemical stability of an API, atorvastatin calcium (AC), in mixtures with the excipients was evaluated by monitoring the appearance of an acid-induced degradant, atorvastatin lactone, under accelerated storage conditions. The extent of lactone formation in AC-excipient mixtures was presented as a function of either solution/suspension pH or pHeq. No lactone formation was observed in mixtures with excipients having pHeq > 6, while the lactone levels were pronounced (> 0.6% after 6 weeks at 50°C/20% RH) with excipients exhibiting pHeq 6, 3-6, and API, were identified based on pHeq measurements. The incompatibility prediction was confirmed in the chemical stability tests using AC as an example of an acid-sensitive API.

  3. Outline of the Desktop Severe Accident Graphic Simulator Module for OPR-1000

    Energy Technology Data Exchange (ETDEWEB)

    Park, S. Y.; Ahn, K. I. [KAERI, Daejeon (Korea, Republic of)

    2015-05-15

    This paper introduce the desktop severe accident graphic simulator module (VMAAP) which is a window-based severe accident simulator using MAAP as its engine. The VMAAP is one of the submodules in SAMEX system (Severe Accident Management Support Expert System) which is a decision support system for use in a severe accident management following an incident at a nuclear power plant. The SAMEX system consists of four major modules as sub-systems: (a) Severe accident risk data base module (SARDB): stores the data of integrated severe accident analysis code results like MAAP and MELCOR for hundreds of high frequency scenarios for the reference plant; (b) Risk-informed severe accident risk data base management module (RI-SARD): provides a platform to identify the initiating event, determine plant status and equipment availability, diagnoses the status of the reactor core, reactor vessel and containment building, and predicts the plant behaviors; (c) Severe accident management simulator module (VMAAP): runs the MAAP4 code with user friendly graphic interface for input deck and output display; (d) On-line severe accident management guidance module (On-line SAMG); provides available accident management strategies with an electronic format. The role of VMAAP in SAMEX can be described as followings. SARDB contains the most of high frequency scenarios based on a level 2 probabilistic safety analysis. Therefore, there is good chance that a real accident sequence is similar to one of the data base cases. In such a case, RI-SARD can predict an accident progression by a scenario-base or symptom-base search depends on the available plant parameter information. Nevertheless, there still may be deviations or variations between the actual scenario and the data base scenario. The deviations can be decreased by using a real-time graphic accident simulator, VMAAP.. VMAAP is a MAAP4-based severe accident simulation model for OPR-1000 plant. It can simulate spectrum of physical processes

  4. JUPITER: Joint Universal Parameter IdenTification and Evaluation of Reliability - An Application Programming Interface (API) for Model Analysis

    Science.gov (United States)

    Banta, Edward R.; Poeter, Eileen P.; Doherty, John E.; Hill, Mary C.

    2006-01-01

    model predictions. * Use calibration methods to modify parameter values and other aspects of the model. * Compare predictions to regulatory limits. * Quantify the uncertainty of predictions based on the results of one or many simulations using inferential or Monte Carlo methods. * Determine how to manage the system to achieve stated objectives. The capabilities provided by the JUPITER API include, for example, communication with process models, parallel computations, compressed storage of matrices, and flexible input capabilities. The input capabilities use input blocks suitable for lists or arrays of data. The input blocks needed for one application can be included within one data file or distributed among many files. Data exchange between different JUPITER API applications or between applications and other programs is supported by data-exchange files. The JUPITER API has already been used to construct a number of applications. Three simple example applications are presented in this report. More complicated applications include the universal inverse code UCODE_2005 (Poeter et al., 2005), the multi-model analysis MMA (Eileen P. Poeter, Mary C. Hill, E.R. Banta, S.W. Mehl, and Steen Christensen, written commun., 2006), and a code named OPR_PPR (Matthew J. Tonkin, Claire R. Tiedeman, Mary C. Hill, and D. Matthew Ely, written communication, 2006). This report describes a set of underlying organizational concepts and complete specifics about the JUPITER API. While understanding the organizational concept presented is useful to understanding the modules, other organizational concepts can be used in applications constructed using the JUPITER API.

  5. Enabling Desktop Nanofabrication with the Targeted Use of Soft Materials

    Science.gov (United States)

    Eichelsdoerfer, Daniel James

    This thesis focuses on the application of soft materials to scanning probe-based molecular printing techniques, such as dip-pen nanolithography (DPN). The selective incorporation of soft materials in place of hard materials in traditional cantilever-based scanning probe lithography (SPL) systems not only enables the deposition of a broader range of materials, but also dramatically lowers the cost while simultaneously increasing the throughput of SPL. Chapter 1 introduces SPL and DPN, and highlights a few recent advances in using DPN to control surface chemical functionality at the nanoscale. In addition to introducing the material deposition capabilities of DPN, Chapter 1 introduces the development of the cantilever-free architecture, a relatively recent paradigm shift in high-throughput SPL. Furthermore, an in-depth synthetic methodology for making the most widely used cantilever-free tip arrays, consisting of elastomeric nanoscale pens adhered to an elastomeric backing layer on a glass slide, is included as an appendix. Chapter 2 discusses the synthesis of metal and metal oxide nanoparticles at specified locations by using DPN to deposit the precursors dispersed in a polymer matrix; after deposition, the precursors are annealed to form single nanoparticles. This work builds on previous soft material-based advances in DPN by utilizing the polymer as a "nanoreactor" to synthesize the desired nanoparticles, where the precursors can diffuse and coalesce into a single nanoparticle within each spot. The process of precursor aggregation and single nanoparticle formation is studied, and it is found that metal precursors follow one of three pathways based upon their reduction potential. Chapter 3 is the first of three chapters that highlights the power of soft materials in the cantilever-free architecture. In particular, Chapter 3 examines the role of the elastomeric backing layer as a compliant spring whose stiffness (as measured by the spring constant, k) can be tuned

  6. Desktop Severe Accident Graphic Simulator Module for CANDU6 : PSAIS

    Energy Technology Data Exchange (ETDEWEB)

    Park, S. Y.; Song, Y. M. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    The ISAAC ((Integrated Severe Accident Analysis Code for CANDU Plant) code is a system level computer code capable of performing integral analyses of potential severe accident progressions in nuclear power plants, whose main purpose is to support a Level 2 probabilistic safety assessment or severe accident management strategy developments. The code has the capability to predict a severe accident progression by modeling the CANDU6- specific systems and the expected physical phenomena based on the current understanding of the unique accident progressions. The code models the sequence of accident progressions from a core heatup, pressure tube/calandria tube rupture after an uncovery from inside and outside, a relocation of the damaged fuel to the bottom of the calandria, debris behavior in the calandria, corium quenching after a debris relocation from the calandria to the calandria vault and an erosion of the calandria vault concrete floor, a hydrogen burn, and a reactor building failure. Along with the thermal hydraulics, the fission product behavior is also considered in the primary system as well as in the reactor building.

  7. High-performance image processing on the desktop

    Science.gov (United States)

    Jordan, Stephen D.

    1996-04-01

    The suitability of computers to the task of medical image visualization for the purposes of primary diagnosis and treatment planning depends on three factors: speed, image quality, and price. To be widely accepted the technology must increase the efficiency of the diagnostic and planning processes. This requires processing and displaying medical images of various modalities in real-time, with accuracy and clarity, on an affordable system. Our approach to meeting this challenge began with market research to understand customer image processing needs. These needs were translated into system-level requirements, which in turn were used to determine which image processing functions should be implemented in hardware. The result is a computer architecture for 2D image processing that is both high-speed and cost-effective. The architectural solution is based on the high-performance PA-RISC workstation with an HCRX graphics accelerator. The image processing enhancements are incorporated into the image visualization accelerator (IVX) which attaches to the HCRX graphics subsystem. The IVX includes a custom VLSI chip which has a programmable convolver, a window/level mapper, and an interpolator supporting nearest-neighbor, bi-linear, and bi-cubic modes. This combination of features can be used to enable simultaneous convolution, pan, zoom, rotate, and window/level control into 1 k by 1 k by 16-bit medical images at 40 frames/second.

  8. Application of Google Maps API service for creating web map of information retrieved from CORINE land cover databases

    Directory of Open Access Journals (Sweden)

    Kilibarda Milan

    2010-01-01

    Full Text Available Today, Google Maps API application based on Ajax technology as standard web service; facilitate users with publication interactive web maps, thus opening new possibilities in relation to the classical analogue maps. CORINE land cover databases are recognized as the fundamental reference data sets for numerious spatial analysis. The theoretical and applicable aspects of Google Maps API cartographic service are considered on the case of creating web map of change in urban areas in Belgrade and surround from 2000. to 2006. year, obtained from CORINE databases.

  9. Drone competition at drone congregation areas in four Apis species

    OpenAIRE

    2005-01-01

    International audience; In Apis mellifera the estimated average number of drones visiting a drone congregation area (DCA) was 11 750 + 2 145. Drones of the species Apis cerana, A. koschevnikovi, A. dorsata and A. mellifera, which pursued a queen dummy moving in circular course, flew in a comet shaped formation. Median numbers of drones in a comet ranged from 9 drones (A. koschevnikovi) to 31 drones (A. mellifera). In none of the species we observed aggression between drones. Drone density beh...

  10. Pengaruh Busur Api Terhadap Kekuatan Dielektrik Gas SF6

    OpenAIRE

    Jhony

    2011-01-01

    Bahan isolasi gas yang sering digunakan adalah gas SF6. Sifat –sifat dari gas SF6 ini tidak berwarna, tidak beracun, tidak berbau. Salah satu pemanfaatan dari gas SF6 ini sebagai bahan isolasi adalah pada pemutus tenaga (circuit breaker). Jika pemutus tenaga SF6 membuka, maka pada sela kontaknya akan terjadi busur api. Busur api akan menaikkan temperatur gas SF6 sehingga ada dugaan gas SF6 mengalami perubahan struktur kimia, sehingga sifat listriknya berubah. Tugas akhir ini ak...

  11. Beginning the 21st century with advanced Automatic Parts Identification (API)

    Science.gov (United States)

    Schramm, Fred; Roxby, Don

    1994-01-01

    Under the direction of the NASA George C. Marshall Space Flight Center, Huntsville, Alabama, the development and commercialization of an advanced Automated Parts Indentification (API) system is being undertaken by Rockwell International Corporation. The new API system is based on a variable sized, machine-readable, two-dimensioanl matrix symbol that can be applied directly onto most metallic and nonmetallic materials using safe, permanent marking methods. Its checkerboard-like structure is the most space efficient of all symbologies. This high data-density symbology can be applied to products of different material sizes and geometries using application-dependent, computer-driven marking devices. The high fidelity markings produced by these devices can then be captured using a specially designed camera linked to any IBM-compatible computer. Applications of compressed symbology technology will reduce costs and improve quality, productivity, and processes in a wide variety of federal and commercial applications.

  12. Genetic reincarnation of workers as queens in the Eastern honeybee Apis cerana.

    Science.gov (United States)

    Holmes, M J; Tan, K; Wang, Z; Oldroyd, B P; Beekman, M

    2015-01-01

    Thelytokous parthenogenesis, or the asexual production of female offspring, is rare in the animal kingdom, but relatively common in social Hymenoptera. However, in honeybees, it is only known to be ubiquitous in one subspecies of Apis mellifera, the Cape honeybee, A. mellifera capensis. Here we report the appearance of queen cells in two colonies of the Eastern honeybee Apis cerana that no longer contained a queen or queen-produced brood to rear queens from. A combination of microsatellite genotyping and the timing of the appearance of these individuals excluded the possibility that they had been laid by the original queen. Based on the genotypes of these individuals, thelytokous production by natal workers is the most parsimonious explanation for their existence. Thus, we present the first example of thelytoky in a honeybee outside A. mellifera. We discuss the evolutionary and ecological consequences of thelytoky in A. cerana, in particular the role thelytoky may play in the recent invasions by populations of this species.

  13. GIANT API: an application programming interface for functional genomics

    Science.gov (United States)

    Roberts, Andrew M.; Wong, Aaron K.; Fisk, Ian; Troyanskaya, Olga G.

    2016-01-01

    GIANT API provides biomedical researchers programmatic access to tissue-specific and global networks in humans and model organisms, and associated tools, which includes functional re-prioritization of existing genome-wide association study (GWAS) data. Using tissue-specific interaction networks, researchers are able to predict relationships between genes specific to a tissue or cell lineage, identify the changing roles of genes across tissues and uncover disease-gene associations. Additionally, GIANT API enables computational tools like NetWAS, which leverages tissue-specific networks for re-prioritization of GWAS results. The web services covered by the API include 144 tissue-specific functional gene networks in human, global functional networks for human and six common model organisms and the NetWAS method. GIANT API conforms to the REST architecture, which makes it stateless, cacheable and highly scalable. It can be used by a diverse range of clients including web browsers, command terminals, programming languages and standalone apps for data analysis and visualization. The API is freely available for use at http://giant-api.princeton.edu. PMID:27098035

  14. GIANT API: an application programming interface for functional genomics.

    Science.gov (United States)

    Roberts, Andrew M; Wong, Aaron K; Fisk, Ian; Troyanskaya, Olga G

    2016-07-08

    GIANT API provides biomedical researchers programmatic access to tissue-specific and global networks in humans and model organisms, and associated tools, which includes functional re-prioritization of existing genome-wide association study (GWAS) data. Using tissue-specific interaction networks, researchers are able to predict relationships between genes specific to a tissue or cell lineage, identify the changing roles of genes across tissues and uncover disease-gene associations. Additionally, GIANT API enables computational tools like NetWAS, which leverages tissue-specific networks for re-prioritization of GWAS results. The web services covered by the API include 144 tissue-specific functional gene networks in human, global functional networks for human and six common model organisms and the NetWAS method. GIANT API conforms to the REST architecture, which makes it stateless, cacheable and highly scalable. It can be used by a diverse range of clients including web browsers, command terminals, programming languages and standalone apps for data analysis and visualization. The API is freely available for use at http://giant-api.princeton.edu.

  15. Design and implementation of personalized desktop for enterprise portal%个性化定制企业门户桌面系统的设计与实现

    Institute of Scientific and Technical Information of China (English)

    蒲菊华; 刘伟; 熊璋

    2011-01-01

    提出了一种为用户提供个性化定制功能的企业门户桌面系统PD4EP(Personalized Desktop for Enterprise Portal).PD4EP划分了门户频道类别并对各类频道需提供的个-性化功能进行了约束,实现了同类别的不同门户频道个性化定制方式的一致化,从而允许用户同时对多个门户频道批量个性化操作.采用了与企业门户具体业务和资源相分离的模块化系统结构,有效降低了门户桌面系统与其他组成单元间的耦合程度,提高了通用性;因此,PD4EP可用于新建企业门户桌面系统,还可以个性化功能插件的形式扩展现有企业门户桌面系统.PD4EP设计了基于控制反转思想的个性化功能操作流程,增强了门户桌面系统对不同开发者开发的门户频道的兼容性.%Personalized desktop for enterprise portal (PD4EP) was presented, which provided personalized customization to every personal user. PD4EP classifies portal channels to some categories and constrains the personalization for each category. Thus personalization for portal channels belonging to the same category can be uniformed and users can customize multiple portal channels in batch at the same time. The modular system structure was used in PD4EP to separate specific enterprise portal business from portal resources, which reduced the coupling between portal desktop system and other portal components while increased the generality of the system. With above characteristics, PD4EP can be used to design a new enterprise portal desktop system, and to expand an existing enterprise portal desktop by plug-in personalized portal channel. Personalization operation processes in PD4EP were based on inversion of control, which enhanced the compatibility between portal desktop system and portal channels which may be developed by different developers.

  16. Variance in spermatozoa number among Apis dorsata drones and among Apis mellifera drones

    OpenAIRE

    Koeniger, Gudrun; KOENIGER, Nikolaus; Tingek, Salim; Phiancharoen, Mananya

    2005-01-01

    International audience; Published estimates of the mean spermatozoa numbers for Apis dorsata drones vary from 1.2 × 106 and 2.4 × 106; the number of spermatozoa per individual drone vary from 0.22 × 106 to 2.65 × 106. Counts presented here revealed 1.19 × 106 + 0.25 × 106 spermatozoa in drones sampled near a colony and 1.59 × 106 + 0.18 × 106 in drones sampled at a drone congregation area (DCA) in Sabah, Borneo. The difference between the two sites is significant. Further, the degree of varia...

  17. Honeybee (Apis mellifera ligustica) drone embryo proteomes.

    Science.gov (United States)

    Li, Jianke; Fang, Yu; Zhang, Lan; Begna, Desalegn

    2011-03-01

    Little attention has been paid to the drone honeybee (Apis mellifera ligustica) which is a haploid individual carrying only the set of alleles that it inherits from its mother. Molecular mechanisms underlying drone embryogenesis are poorly understood. This study evaluated protein expression profiles of drone embryogenesis at embryonic ages of 24, 48 and 72h. More than 100 reproducible proteins were analyzed by mass spectrometry on 2D electrophoresis gels. Sixty-two proteins were significantly changed at the selected three experimental age points. Expression of the metabolic energy requirement-related protein peaked at the embryonic age of 48h, whereas development and metabolizing amino acid-related proteins expressed optimally at 72h. Cytoskeleton, protein folding and antioxidant-related proteins were highly expressed at 48 and 72h. Protein networks of the identified proteins were constructed and protein expressions were validated at the transcription level. This first proteomic study of drone embryogenesis in the honeybee may provide geneticists an exact timetable and candidate protein outline for further manipulations of drone stem cells.

  18. The Apis mellifera Filamentous Virus Genome

    Directory of Open Access Journals (Sweden)

    Laurent Gauthier

    2015-07-01

    Full Text Available A complete reference genome of the Apis mellifera Filamentous virus (AmFV was determined using Illumina Hiseq sequencing. The AmFV genome is a double stranded DNA molecule of approximately 498,500 nucleotides with a GC content of 50.8%. It encompasses 247 non-overlapping open reading frames (ORFs, equally distributed on both strands, which cover 65% of the genome. While most of the ORFs lacked threshold sequence alignments to reference protein databases, twenty-eight were found to display significant homologies with proteins present in other large double stranded DNA viruses. Remarkably, 13 ORFs had strong similarity with typical baculovirus domains such as PIFs (per os infectivity factor genes: pif-1, pif-2, pif-3 and p74 and BRO (Baculovirus Repeated Open Reading Frame. The putative AmFV DNA polymerase is of type B, but is only distantly related to those of the baculoviruses. The ORFs encoding proteins involved in nucleotide metabolism had the highest percent identity to viral proteins in GenBank. Other notable features include the presence of several collagen-like, chitin-binding, kinesin and pacifastin domains. Due to the large size of the AmFV genome and the inconsistent affiliation with other large double stranded DNA virus families infecting invertebrates, AmFV may belong to a new virus family.

  19. The Apis mellifera Filamentous Virus Genome.

    Science.gov (United States)

    Gauthier, Laurent; Cornman, Scott; Hartmann, Ulrike; Cousserans, François; Evans, Jay D; de Miranda, Joachim R; Neumann, Peter

    2015-07-09

    A complete reference genome of the Apis mellifera Filamentous virus (AmFV) was determined using Illumina Hiseq sequencing. The AmFV genome is a double stranded DNA molecule of approximately 498,500 nucleotides with a GC content of 50.8%. It encompasses 247 non-overlapping open reading frames (ORFs), equally distributed on both strands, which cover 65% of the genome. While most of the ORFs lacked threshold sequence alignments to reference protein databases, twenty-eight were found to display significant homologies with proteins present in other large double stranded DNA viruses. Remarkably, 13 ORFs had strong similarity with typical baculovirus domains such as PIFs (per os infectivity factor genes: pif-1, pif-2, pif-3 and p74) and BRO (Baculovirus Repeated Open Reading Frame). The putative AmFV DNA polymerase is of type B, but is only distantly related to those of the baculoviruses. The ORFs encoding proteins involved in nucleotide metabolism had the highest percent identity to viral proteins in GenBank. Other notable features include the presence of several collagen-like, chitin-binding, kinesin and pacifastin domains. Due to the large size of the AmFV genome and the inconsistent affiliation with other large double stranded DNA virus families infecting invertebrates, AmFV may belong to a new virus family.

  20. Teaching Online or On-Campus? – What Students Say About Desktop Videoconferencing

    Directory of Open Access Journals (Sweden)

    Anders Grov Nilsen

    2013-06-01

    Full Text Available In order to refine online teaching environments, we ask: What do in-service student teachers (n=32 and master’s degree students (n=24 say about desktop videoconferencing (DVC, and how has DVC influenced online teaching and learning? 56 students have completed a survey. Focus group interviews (n=11 and recordings from lessons were also part of the data collected. Our students say that they can cope with the practical and technological issues. The responses indicate there are changes according to student attendance when using DVC.

  1. An evaluation of international nursing education using interactive desktop video conferencing.

    Science.gov (United States)

    Waddell, D L; Tronsgard, B A; Smith, A; Smith, G

    1999-01-01

    Evolving computer technology has opened the door to unique and previously unavailable educational experiences. The use of one form of distance learning enabled undergraduate nursing students in the United States and England to participate in a short course on women's health issues. The nursing faculty at two universities, one in the United States and the other in England, collaborated on an international nursing education project. The delivery device was interactive desktop video conferencing (DTV). The focus of this article is on the evaluation of the project with recommendations about how best to use DTV in international nursing education.

  2. The biochemical properties of the Arabidopsis ecto-nucleoside triphosphate diphosphohydrolase AtAPY1 contradict a direct role in purinergic signaling.

    Directory of Open Access Journals (Sweden)

    Carolin Massalski

    Full Text Available The Arabidopsis E-NTPDase (ecto-nucleoside triphosphate diphosphohydrolase AtAPY1 was previously shown to be involved in growth and development, pollen germination and stress responses. It was proposed to perform these functions through regulation of extracellular ATP signals. However, a GFP-tagged version was localized exclusively in the Golgi and did not hydrolyze ATP. In this study, AtAPY1 without the bulky GFP-tag was biochemically characterized with regard to its suggested role in purinergic signaling. Both the full-length protein and a soluble form without the transmembrane domain near the N-terminus were produced in HEK293 cells. Of the twelve nucleotide substrates tested, only three--GDP, IDP and UDP--were hydrolyzed, confirming that ATP was not a substrate of AtAPY1. In addition, the effects of pH, divalent metal ions, known E-NTPDase inhibitors and calmodulin on AtAPY1 activity were analyzed. AtAPY1-GFP extracted from transgenic Arabidopsis seedlings was included in the analyses. All three AtAPY1 versions exhibited very similar biochemical properties. Activity was detectable in a broad pH range, and Ca(2+, Mg(2+ and Mn(2+ were the three most efficient cofactors. Of the inhibitors tested, vanadate was the most potent one. Surprisingly, sulfonamide-based inhibitors shown to inhibit other E-NTPDases and presumed to inhibit AtAPY1 as well were not effective. Calmodulin stimulated the activity of the GFP-tagless membranous and soluble AtAPY1 forms about five-fold, but did not alter their substrate specificities. The apparent Km values obtained with AtAPY1-GFP indicate that AtAPY1 is primarily a GDPase. A putative three-dimensional structural model of the ecto-domain is presented, explaining the potent inhibitory potential of vanadate and predicting the binding mode of GDP. The found substrate specificity classifies AtAPY1 as a nucleoside diphosphatase typical of N-terminally anchored Golgi E-NTPDases and negates a direct function in

  3. blend4php: a PHP API for galaxy.

    Science.gov (United States)

    Wytko, Connor; Soto, Brian; Ficklin, Stephen P

    2017-01-01

    Galaxy is a popular framework for execution of complex analytical pipelines typically for large data sets, and is a commonly used for (but not limited to) genomic, genetic and related biological analysis. It provides a web front-end and integrates with high performance computing resources. Here we report the development of the blend4php library that wraps Galaxy's RESTful API into a PHP-based library. PHP-based web applications can use blend4php to automate execution, monitoring and management of a remote Galaxy server, including its users, workflows, jobs and more. The blend4php library was specifically developed for the integration of Galaxy with Tripal, the open-source toolkit for the creation of online genomic and genetic web sites. However, it was designed as an independent library for use by any application, and is freely available under version 3 of the GNU Lesser General Public License (LPGL v3.0) at https://github.com/galaxyproject/blend4phpDatabase URL: https://github.com/galaxyproject/blend4php.

  4. Web API for biology with a workflow navigation system.

    Science.gov (United States)

    Kwon, Yeondae; Shigemoto, Yasumasa; Kuwana, Yoshikazu; Sugawara, Hideaki

    2009-07-01

    DNA Data Bank of Japan (DDBJ) provides Web-based systems for biological analysis, called Web APIs for biology (WABI). So far, we have developed over 20 SOAP services and several workflows that consist of a series of method invocations. In this article, we present newly developed services of WABI, that is, REST-based Web services, additional workflows and a workflow navigation system. Each Web service and workflow can be used as a complete service or a building block for programmers to construct more complex information processing systems. The workflow navigation system aims to help non-programming biologists perform analysis tasks by providing next applicable services on Web browsers according to the output of a previously selected service. With this function, users can apply multiple services consecutively only by following links without any programming or manual copy-and-paste operations on Web browsers. The listed services are determined automatically by the system referring to the dictionaries of service categories, the input/output types of services and HTML tags. WABI and the workflow navigation system are freely accessible at http://www.xml.nig.ac.jp/index.html and http://cyclamen.ddbj.nig.ac.jp/, respectively.

  5. blend4php: a PHP API for galaxy

    Science.gov (United States)

    Wytko, Connor; Soto, Brian; Ficklin, Stephen P.

    2017-01-01

    Galaxy is a popular framework for execution of complex analytical pipelines typically for large data sets, and is a commonly used for (but not limited to) genomic, genetic and related biological analysis. It provides a web front-end and integrates with high performance computing resources. Here we report the development of the blend4php library that wraps Galaxy’s RESTful API into a PHP-based library. PHP-based web applications can use blend4php to automate execution, monitoring and management of a remote Galaxy server, including its users, workflows, jobs and more. The blend4php library was specifically developed for the integration of Galaxy with Tripal, the open-source toolkit for the creation of online genomic and genetic web sites. However, it was designed as an independent library for use by any application, and is freely available under version 3 of the GNU Lesser General Public License (LPGL v3.0) at https://github.com/galaxyproject/blend4php. Database URL: https://github.com/galaxyproject/blend4php PMID:28077564

  6. Manipulating API and AOD data to distinguish transportation of aerosol at high altitude in Penang, Malaysia

    Science.gov (United States)

    Tan, F.; Lim, H. S.; Abdullah, K.; Yoon, T. L.; Matjafri, M. Z.; Holben, B.

    2014-02-01

    Air pollution index (API) is an index commonly used in Malaysia to determine the air quality level. It is a ground truth data measurement which is unable to unambiguously quantify air quality level at higher atmosphere. On the other hand, aerosol optical depth (AOD) from AERONET data obtained using sun photometer provides reading of the air quality for a column of atmosphere from ground surface. We first determine the quantitative correlation between the API and AOD data collected in Penang, Malaysia, between January - September, 2012, using two independent methods, one based on regression analysis and the other interpolation. Our purpose is to establish a systematic numerical procedure to determine whether aerosol transported in high altitude from other location has occurred. Two independent methods for establishing the quantitative relationship between the API and AOD data were used as a way to facilitate the verification of our approach. In our method, data from southwest monsoon period (August to September) were used as "calibration dataset" to establish the quantitative correlation between the AOD and API data. The established calibrated coefficients is then used to predict the AOD of other months, which are then compared against the data actually measured. Discrepancy between the predicted and measured AOD data can then be interpreted as an indication of whether the atmosphere at high altitude is polluted by aerosol transported from other location. If the predicted AOD is much larger than that measured, back trajectory analysis was applied to identify the aerosol transported source. This procedure is very helpful to investigate the aerosol transportation and distribution patterns during monsoon and non monsoon periods.

  7. Studies of the eddy structure in the lower ionosphere by the API technique

    Science.gov (United States)

    Bakhmetieva, Nataliya V.; Grigoriev, Gennadii I.; Lapin, Victor G.

    2016-07-01

    We present a new application of the API technique to study of turbulent phenomena in the lower ionosphere. The main objective of these studies is experimental diagnostics of natural ordered eddy structures at the altitudes of the mesosphere and lower thermosphere, such as those that occur when internal gravity waves propagate in stratified flows in the atmospheric boundary layer. To this end, we considered the impact of eddy motions in the mesosphere and lower thermosphere on the relaxation time and the frequency of the signal scattered by periodic irregularities. Theoretical study of eddy structures base on experiments using SURA heating facility (56,14 N; 44,1 W). It is known, artificial periodic irregularities (APIs) are formed in the field of the powerful standing wave as a result of the interference of the incident wave and reflected from the ionosphere (Belikovich et al., Ionospheric Research by Means of Artificial Periodic Irregularities - 2002. Katlenburg-Lindau, Germany. Copernicus GmbH. 160 p.). The relaxation or decay of the periodic structure is specified by the ambipolar diffusion process. The atmospheric turbulence causes reduction of the amplitude and decay time of the API scattered signal in comparison with the diffusion time. We found a relation between the eddy period and the characteristic decay time of scattered signal, for which the synchronism of the waves scattered by a periodic structure is broken. Besides, it is shown, when the eddy structure moves by a horizontal wind exists at these heights, the frequency of the radio wave scattered by API structure will periodically increase and decrease compared with the frequency of the radiated diagnostic (probing) radio-wave. The work was supported by the Russian Science Foundation under grant No 14-12-00556.

  8. Inhibiting DNA methylation alters olfactory extinction but not acquisition learning in Apis cerana and Apis mellifera.

    Science.gov (United States)

    Gong, Zhiwen; Wang, Chao; Nieh, James C; Tan, Ken

    2016-07-01

    DNA methylation plays a key role in invertebrate acquisition and extinction memory. Honey bees have excellent olfactory learning, but the role of DNA methylation in memory formation has, to date, only been studied in Apis mellifera. We inhibited DNA methylation by inhibiting DNA methyltransferase (DNMT) with zebularine (zeb) and studied the resulting effects upon olfactory acquisition and extinction memory in two honey bee species, Apis cerana and A. mellifera. We used the proboscis extension reflex (PER) assay to measure memory. We provide the first demonstration that DNA methylation is also important in the olfactory extinction learning of A. cerana. DNMT did not reduce acquisition learning in either species. However, zeb bidirectionally and differentially altered extinction learning in both species. In particular, zeb provided 1h before acquisition learning improved extinction memory retention in A. mellifera, but reduced extinction memory retention in A. cerana. The reasons for these differences are unclear, but provide a basis for future studies to explore species-specific differences in the effects of methylation on memory formation.

  9. Super-Atmospheric Pressure Ion Sources: Application and Coupling to API Mass Spectrometer.

    Science.gov (United States)

    Chen, Lee Chuin; Rahman, Md Matiur; Hiraoka, Kenzo

    2014-01-01

    Pressurizing the ionization source to gas pressure greater than atmospheric pressure is a new tactic aimed at further improving the performance of atmospheric pressure ionization (API) sources. In principle, all API sources, such as ESI, APCI and AP-MALDI, can be operated at pressure higher than 1 atm if suitable vacuum interface is available. The gas pressure in the ion source can have different role for different ionization. For example, in the case of ESI, stable electrospray could be sustained for high surface tension liquid (e.g., pure water) under super-atmospheric pressure, owing to the absence of electric discharge. Even for nanoESI, which is known to work well with aqueous solution, its stability and sensitivity were found to be enhanced, particularly in the negative mode when the ion source was pressurized. For the gas phase ionization like APCI, measurement of gaseous compound also showed an increase in ion intensity with the ion source pressure until an optimum pressure at around 4-5 atm. The enhancement was due to the increased collision frequency among reactant ion and analyte that promoted the ion/molecule reaction and a higher intake rate of gas to the mass spectrometer. Because the design of vacuum interface for API instrument is based on the upstream pressure of 1 atm, some coupling aspects need to be considered when connecting the high pressure ion source to the mass spectrometer. Several coupling strategies are discussed in this paper.

  10. College students' self-discrepancy on the Internet, from the perspectives of desktop practices, self-control, and academic training.

    Science.gov (United States)

    Tzeng, Jeng-Yi

    2010-10-01

    The self-discrepancy theory argues that perceived discrepancy between one's actual self and ideal self may induce anxiety, and that this in turn may motivate people to reduce or eliminate this perceived discrepancy by changing their behaviors. Based on this theory, this study investigated how college students perceived discrepancies between their actual and their reported ideal uses of the Internet. Their Internet use was examined on three levels: the grand level (i.e., hours spent online per week), the activity level (i.e., hours spent engaging in certain online activities per week), and the tool level (i.e., hours spent using certain Internet tools per week). Three particular factors were also selected for investigation: the participants' different desktop practices, levels of academic training, and exertions of self-control. The results indicate that the participants' perceptions of actual versus ideal discrepancies were shaped by the different levels (i.e., grand, activity, tool) of their Internet use. Additionally, this study shows that perceived self-discrepancy relating to the time that college students spend on the Internet may not be a problem in itself, but it may symbolize more profound psychological or behavioral factors that need to be addressed.

  11. A quick guide to API 510 certified pressure vessel inspector syllabus example questions and worked answers

    CERN Document Server

    Matthews, Clifford

    2010-01-01

    The API Individual Certification Programs (ICPs) are well established worldwide in the oil, gas, and petroleum industries. This Quick Guide is unique in providing simple, accessible and well-structured guidance for anyone studying the API 510 Certified Pressure Vessel Inspector syllabus by summarizing and helping them through the syllabus and providing multiple example questions and worked answers.Technical standards are referenced from the API 'body of knowledge' for the examination, i.e. API 510 Pressure vessel inspection, alteration, rerating; API 572 Pressure vessel inspection; API

  12. Fabrication of low cost soft tissue prostheses with the desktop 3D printer.

    Science.gov (United States)

    He, Yong; Xue, Guang-huai; Fu, Jian-zhong

    2014-11-27

    Soft tissue prostheses such as artificial ear, eye and nose are widely used in the maxillofacial rehabilitation. In this report we demonstrate how to fabricate soft prostheses mold with a low cost desktop 3D printer. The fabrication method used is referred to as Scanning Printing Polishing Casting (SPPC). Firstly the anatomy is scanned with a 3D scanner, then a tissue casting mold is designed on computer and printed with a desktop 3D printer. Subsequently, a chemical polishing method is used to polish the casting mold by removing the staircase effect and acquiring a smooth surface. Finally, the last step is to cast medical grade silicone into the mold. After the silicone is cured, the fine soft prostheses can be removed from the mold. Utilizing the SPPC method, soft prostheses with smooth surface and complicated structure can be fabricated at a low cost. Accordingly, the total cost of fabricating ear prosthesis is about $30, which is much lower than the current soft prostheses fabrication methods.

  13. Fabrication of low cost soft tissue prostheses with the desktop 3D printer

    Science.gov (United States)

    He, Yong; Xue, Guang-Huai; Fu, Jian-Zhong

    2014-11-01

    Soft tissue prostheses such as artificial ear, eye and nose are widely used in the maxillofacial rehabilitation. In this report we demonstrate how to fabricate soft prostheses mold with a low cost desktop 3D printer. The fabrication method used is referred to as Scanning Printing Polishing Casting (SPPC). Firstly the anatomy is scanned with a 3D scanner, then a tissue casting mold is designed on computer and printed with a desktop 3D printer. Subsequently, a chemical polishing method is used to polish the casting mold by removing the staircase effect and acquiring a smooth surface. Finally, the last step is to cast medical grade silicone into the mold. After the silicone is cured, the fine soft prostheses can be removed from the mold. Utilizing the SPPC method, soft prostheses with smooth surface and complicated structure can be fabricated at a low cost. Accordingly, the total cost of fabricating ear prosthesis is about $30, which is much lower than the current soft prostheses fabrication methods.

  14. Security Risk Minimization for Desktop and Mobile Software Systems. An In-Depth Analysis

    Directory of Open Access Journals (Sweden)

    Florina Camelia PUICAN

    2014-01-01

    Full Text Available In an extremely rapid growing industry such as the information technology nowadays, continuous and efficient workflows need to be established within any integrated enterprise or consumer software system. Taking into consideration the actual trend of data and information migrating to mobile devices, which have became more than just simple gadgets, the security threats and vulnerabilities of software products have created a new playground for attackers, especially when the system offers cross-platform (desktop and mobile functionalities and applicability. In this context, the paper proposes an in depth analysis over some of the weaknesses software systems present, providing also a set of solutions for minimizing and mitigating the risks of any solution, be it mobile or desktop. Subsequently, even though consumer and enterprise systems have fundamentally different structures and architectures (due to the different needs of the end user, data loss or information leakage may and will affect any type of machine if proper securization of the systems is not taken into consideration, therefore risk minimization through an in-depth analysis of any integrated software system becomes mandatory and needs extensive care.

  15. Effects of boundary-layer separation controllers on a desktop fume hood.

    Science.gov (United States)

    Huang, Rong Fung; Chen, Jia-Kun; Hsu, Ching Min; Hung, Shuo-Fu

    2016-10-02

    A desktop fume hood installed with an innovative design of flow boundary-layer separation controllers on the leading edges of the side plates, work surface, and corners was developed and characterized for its flow and containment leakage characteristics. The geometric features of the developed desktop fume hood included a rearward offset suction slot, two side plates, two side-plate boundary-layer separation controllers on the leading edges of the side plates, a slanted surface on the leading edge of the work surface, and two small triangular plates on the upper left and right corners of the hood face. The flow characteristics were examined using the laser-assisted smoke flow visualization technique. The containment leakages were measured by the tracer gas (sulphur hexafluoride) detection method on the hood face plane with a mannequin installed in front of the hood. The results of flow visualization showed that the smoke dispersions induced by the boundary-layer separations on the leading edges of the side plates and work surface, as well as the three-dimensional complex flows on the upper-left and -right corners of the hood face, were effectively alleviated by the boundary-layer separation controllers. The results of the tracer gas detection method with a mannequin standing in front of the hood showed that the leakage levels were negligibly small (≤0.003 ppm) at low face velocities (≥0.19 m/s).

  16. When API Mass Spectrometry Meets Super Atmospheric Pressure Ion Sources.

    Science.gov (United States)

    Chen, Lee Chuin

    2015-01-01

    In a tutorial paper on the application of free-jet technique for API-MS, John Fenn mentioned that "…for a number of years and a number of reasons, it has been found advantageous in many situations to carry out the ionization process in gas at pressures up to 1000 Torr or more" (Int. J. Mass Spectrom. 200: 459-478, 2000). In fact, the first ESI mass spectrometer constructed by Yamashita and Fenn had a counter-flow curtain gas source at 1050 Torr (ca. 1.4 atm) to sweep away the neutral (J. Phys. Chem. 88: 4451-4459, 1984). For gaseous ionization using electrospray plume, theoretical analysis also shows that "super-atmospheric operation would be more preferable in space-charge-limited situations."(Int. J. Mass Spectrom. 300: 182-193, 2011). However, electrospray and the corona-based chemical ion source (APCI) in most commercial instrument are basically operated under an atmospheric pressure ambient, perhaps out of the concern of safety, convenience and simplicity in maintenance. Running the ion source at pressure much higher than 1 atm is not so common, but had been done by a number of groups as well as in our laboratory. A brief review on these ion sources will be given in this paper.

  17. SIP APIs for Voice and Video Communications on the Web

    CERN Document Server

    Davids, Carol; Singh, Kundan; Sinnreich, Henry; Wimmreuter, Wilhelm

    2011-01-01

    Existing standard protocols for the web and Internet telephony fail to deliver real-time interactive communication from within a web browser. In particular, the client-server web protocol over reliable TCP is not always suitable for end-to-end low latency media path needed for interactive voice and video communication. To solve this, we compare the available platform options using the existing technologies such as modifying the web programming language and protocol, using an existing web browser plugin, and a separate host resident application that the web browser can talk to. We argue that using a separate application as an adaptor is a promising short term as well as long-term strategy for voice and video communications on the web. Our project aims at developing the open technology and sample implementations for web-based real-time voice and video communication applications. We describe the architecture of our project including (1) a RESTful web communication API over HTTP inspired by SIP message flows, (2)...

  18. Comparative sucrose responsiveness in Apis mellifera and A. cerana foragers.

    Science.gov (United States)

    Yang, Wenchao; Kuang, Haiou; Wang, Shanshan; Wang, Jie; Liu, Wei; Wu, Zhenhong; Tian, Yuanyuan; Huang, Zachary Y; Miao, Xiaoqing

    2013-01-01

    In the European honey bee, Apis mellifera, pollen foragers have a higher sucrose responsiveness than nectar foragers when tested using a proboscis extension response (PER) assay. In addition, Africanized honey bees have a higher sucrose responsiveness than European honey bees. Based on the biology of the Eastern honey bee, A. cerana, we hypothesized that A. cerana should also have a higher responsiveness to sucrose than A. mellifera. To test this hypothesis, we compared the sucrose thresholds of pollen foragers and nectar foragers in both A. cerana and A. mellifera in Fujian Province, China. Pollen foragers were more responsive to sucrose than nectar foragers in both species, consistent with previous studies. However, contrary to our hypothesis, A. mellifera was more responsive than A. cerana. We also demonstrated that this higher sucrose responsiveness in A. mellifera was not due to differences in the colony environment by co-fostering two species of bees in the same mixed-species colonies. Because A. mellifera foragers were more responsive to sucrose, we predicted that their nectar foragers should bring in less concentrated nectar compared to that of A. cerana. However, we found no differences between the two species. We conclude that A. cerana shows a different pattern in sucrose responsiveness from that of Africanized bees. There may be other mechanisms that enable A. cerana to perform well in areas with sparse nectar resources.

  19. Thermodynamic phase behavior of API/polymer solid dispersions.

    Science.gov (United States)

    Prudic, Anke; Ji, Yuanhui; Sadowski, Gabriele

    2014-07-07

    To improve the bioavailability of poorly soluble active pharmaceutical ingredients (APIs), these materials are often integrated into a polymer matrix that acts as a carrier. The resulting mixture is called a solid dispersion. In this work, the phase behaviors of solid dispersions were investigated as a function of the API as well as of the type and molecular weight of the carrier polymer. Specifically, the solubility of artemisinin and indomethacin was measured in different poly(ethylene glycol)s (PEG 400, PEG 6000, and PEG 35000). The measured solubility data and the solubility of sulfonamides in poly(vinylpyrrolidone) (PVP) K10 and PEG 35000 were modeled using the perturbed-chain statistical associating fluid theory (PC-SAFT). The results show that PC-SAFT predictions are in a good accordance with the experimental data, and PC-SAFT can be used to predict the whole phase diagram of an API/polymer solid dispersion as a function of the kind of API and polymer and of the polymer's molecular weight. This remarkably simplifies the screening process for suitable API/polymer combinations.

  20. Space Shuttle Main Engine Joint Data List Applying Today's Desktop Technologies to Facilitate Engine Processing

    Science.gov (United States)

    Jacobs, Kenneth; Drobnick, John; Krell, Don; Neuhart, Terry; McCool, A. (Technical Monitor)

    2001-01-01

    Boeing-Rocketdyne's Space Shuttle Main Engine (SSME) is the world's first large reusable liquid rocket engine. The space shuttle propulsion system has three SSMEs, each weighing 7,400 lbs and providing 470,000 lbs of thrust at 100% rated power level. To ensure required safety and reliability levels are achieved with the reusable engines, each SSME is partially disassembled, inspected, reassembled, and retested at Kennedy Space Center between each flight. Maintenance processing must be performed very carefully to replace any suspect components, maintain proper engine configuration, and avoid introduction of contaminants that could affect performance and safety. The long service life, and number, complexity, and pedigree of SSME components makes logistics functions extremely critical. One SSME logistics challenge is documenting the assembly and disassembly of the complex joint configurations. This data (joint nomenclature, seal and fastener identification and orientation, assembly sequence, fastener torques, etc.) must be available to technicians and engineers during processing. Various assembly drawings and procedures contain this information, but in this format the required (practical) joint data can be hard to find, due to the continued use of archaic engineering drawings and microfilm for field site use. Additionally, the release system must traverse 2,500 miles between design center and field site, across three time zones, which adds communication challenges and time lags for critical engine configuration data. To aid in information accessibility, a Joint Data List (JDL) was developed that allows efficient access to practical joint data. The published JDL has been a very useful logistics product, providing illustrations and information on the latest SSME configuration. The JDL identifies over 3,350 unique parts across seven fluid systems, over 300 joints, times two distinct engine configurations. The JDL system was recently converted to a web-based, navigable

  1. 桌面3D打印机结构分析及机体设计研究%RESEARCH AND ANALYSIS ON THE BODY STRUCTURE DESIGN OF DESKTOP 3D PRINTER

    Institute of Scientific and Technical Information of China (English)

    牛晰

    2015-01-01

    3D打印技术作为个性化商品定制的重要生产手段,其自身的结构和机体的设计代表着该项技术的发展程度,本文基于对开放式桌面3D打印机结构以及封闭式桌面3D打印机结构进行整体分析的前提下,对桌面3D打印机机体外观造型进行了整体的设计,并同时从桌面3D打印机的应用材料、应用软件及打印效果和未来发展趋势上进行了综述。%3D printing technology serves as an important means of production of personalized customization of goods. Its own structure and the design of engine body represent the degree of development of the technology. Based on the premise of the overal analysis of the open desktop 3D printer structure and closed desktop 3D printer structure, this paper generaly designs the body appearance of desktop 3D printer, and at the same time carries out a review from the point of the applied material, application software and the printing effect and the future development trend.

  2. Contributions to Desktop Grid Computing : From High Throughput Computing to Data-Intensive Sciences on Hybrid Distributed Computing Infrastructures

    OpenAIRE

    Fedak, Gilles

    2015-01-01

    Since the mid 90’s, Desktop Grid Computing - i.e the idea of using a large number of remote PCs distributed on the Internet to execute large parallel applications - has proved to be an efficient paradigm to provide a large computational power at the fraction of the cost of a dedicated computing infrastructure.This document presents my contributions over the last decade to broaden the scope of Desktop Grid Computing. My research has followed three different directions. The first direction has ...

  3. Vitellogenins are new high molecular weight components and allergens (Api m 12 and Ves v 6 of Apis mellifera and Vespula vulgaris venom.

    Directory of Open Access Journals (Sweden)

    Simon Blank

    Full Text Available BACKGROUND/OBJECTIVES: Anaphylaxis due to hymenoptera stings is one of the most severe clinical outcomes of IgE-mediated hypersensitivity reactions. Although allergic reactions to hymenoptera stings are often considered as a general model for the underlying principles of allergic disease, venom immunotherapy is still hampered by severe systemic side effects and incomplete protection. The identification and detailed characterization of all allergens of hymenoptera venoms might result in an improvement in this field and promote the detailed understanding of the allergological mechanism. Our aim was the identification and detailed immunochemical and allergological characterization of the low abundant IgE-reactive 200 kDa proteins of Apis mellifera and Vespula vulgaris venom. METHODS/PRINCIPAL FINDINGS: Tandem mass spectrometry-based sequencing of a 200 kDa venom protein yielded peptides that could be assigned to honeybee vitellogenin. The coding regions of the honeybee protein as well as of the homologue from yellow jacket venom were cloned from venom gland cDNA. The newly identified 200 kDa proteins share a sequence identity on protein level of 40% and belong to the family of vitellogenins, present in all oviparous animals, and are the first vitellogenins identified as components of venom. Both vitellogenins could be recombinantly produced as soluble proteins in insect cells and assessed for their specific IgE reactivity. The particular vitellogenins were recognized by approximately 40% of sera of venom-allergic patients even in the absence of cross-reactive carbohydrate determinants. CONCLUSION: With the vitellogenins of Apis mellifera and Vespula vulgaris venom a new homologous pair of venom allergens was identified and becomes available for future applications. Due to their allergenic properties the honeybee and the yellow jacket venom vitellogenin were designated as allergens Api m 12 and Ves v 6, respectively.

  4. Development of API 5 CT grade P110 steel casing; Desenvolvimento de tubos casing API 5 CT grau P110

    Energy Technology Data Exchange (ETDEWEB)

    Kojima, Sergio Seijo; Roza, Juliana Espinossi

    2003-07-01

    This paper has as objective to discuss the results gotten in experiences carried through in industrial scale for the development of pipes class API 5CT P110 (1), with 244 mm of diameter and 12 mm of thickness. The pipes were welded longitudinally by process ERW (electric resistance welding) and submitted to quenching and tempering heat treatments. A C-Mn-Cr alloy with adequate quenching ability was used for the attainment of a martensite microstructure after quenching. The pipes at a temperature of 880 deg C were quenched in water and subsequently tempered at 515 deg C. The integrity of the weld region was evaluated through non destructive tests and flattening tests, Charpy impact tests and fracture toughness tests (CTOD). The pipes achieved the tension properties stipulated in the standard (yield strength bigger limit of 758 Mpa), and also the energy in the Charpy impact test (transversal), considering that the energy value obtained was 55 J (at 0 deg C) for base metal and 44 J in the weld metal. (author)

  5. Nosema ceranae in drone honey bees (Apis mellifera).

    Science.gov (United States)

    Traver, Brenna E; Fell, Richard D

    2011-07-01

    Nosema ceranae is a microsporidian intracellular parasite of honey bees, Apis mellifera. Previously Nosema apis was thought to be the only cause of nosemosis, but it has recently been proposed that N. ceranae is displacing N. apis. The rapid spread of N. ceranae could be due to additional transmission mechanisms, as well as higher infectivity. We analyzed drones for N. ceranae infections using duplex qPCR with species specific primers and probes. We found that both immature and mature drones are infected with N. ceranae at low levels. This is the first report detecting N. ceranae in immature bees. Our data suggest that because drones are known to drift from their parent hives to other hives, they could provide a means for disease spread within and between apiaries.

  6. A Process Analytical Technology (PAT) approach to control a new API manufacturing process: development, validation and implementation.

    Science.gov (United States)

    Schaefer, Cédric; Clicq, David; Lecomte, Clémence; Merschaert, Alain; Norrant, Edith; Fotiadu, Frédéric

    2014-03-01

    Pharmaceutical companies are progressively adopting and introducing Process Analytical Technology (PAT) and Quality-by-Design (QbD) concepts promoted by the regulatory agencies, aiming the building of the quality directly into the product by combining thorough scientific understanding and quality risk management. An analytical method based on near infrared (NIR) spectroscopy was developed as a PAT tool to control on-line an API (active pharmaceutical ingredient) manufacturing crystallization step during which the API and residual solvent contents need to be precisely determined to reach the predefined seeding point. An original methodology based on the QbD principles was designed to conduct the development and validation of the NIR method and to ensure that it is fitted for its intended use. On this basis, Partial least squares (PLS) models were developed and optimized using chemometrics methods. The method was fully validated according to the ICH Q2(R1) guideline and using the accuracy profile approach. The dosing ranges were evaluated to 9.0-12.0% w/w for the API and 0.18-1.50% w/w for the residual methanol. As by nature the variability of the sampling method and the reference method are included in the variability obtained for the NIR method during the validation phase, a real-time process monitoring exercise was performed to prove its fit for purpose. The implementation of this in-process control (IPC) method on the industrial plant from the launch of the new API synthesis process will enable automatic control of the final crystallization step in order to ensure a predefined quality level of the API. In addition, several valuable benefits are expected including reduction of the process time, suppression of a rather difficult sampling and tedious off-line analyses.

  7. Desktop analysis of potential impacts of visitor use: a case study for the highest park in the Southern Hemisphere.

    Science.gov (United States)

    Barros, Agustina; Pickering, Catherine; Gudes, Ori

    2015-03-01

    Nature-based tourism and recreation activities have a range of environmental impacts, but most protected area agencies have limited capacity to assess them. To prioritise where and what impacts to monitor and manage, we conducted a desktop assessment using Geographical Information Systems (GIS) by combining recreation ecology research with data on visitor usage and key environmental features for a popular protected area used for mountaineering and trekking, Aconcagua Provincial Park (2400-6962 m a.s.l.) in the Andes of Argentina. First, we integrated visitor data from permits with environmental data using GIS. We then identified key impact indicators for different activities based on the recreation ecology literature. Finally, we integrated this data to identify likely ecological impacts based on the types of activities, amount of use and altitudinal zones. Visitors only used 2% of the Park, but use was concentrated in areas of high conservation value including in alpine meadows and glacier lakes. Impacts on water resources were likely to be concentrated in campsites from the intermediate to the nival/glacial zones of the Park while impacts on terrestrial biodiversity were likely to be more severe in the low and intermediate alpine zones (2400-3800 m a.s.l.). These results highlight how visitor data can be used to identify priority areas for on-ground assessment of impacts in key locations. Improvements to the management of visitors in this Park involves more effective ways of dealing with water extraction and human waste in high altitude campsites and the impacts of hikers and pack animals in the low and intermediate alpine zones.

  8. Hydrogen sulfide corrosion of weld regions in API X52 steel; Corrosion por acido sulfhidrico de las regiones de soldadura en acero API X52

    Energy Technology Data Exchange (ETDEWEB)

    Arenas-Martinez, L.F [Universidad Autonoma de Coahuila, Coahuila (Mexico)]. E-mail: fernando.arenas@uadec.edu.mx; Garcia-Cerecero, G. [Corporacion Mexicana de Investigacion en Materiales S.A. de C.V., Saltillo, Coahuila (Mexico)]. E-mail: ggarcia@comimsa.com

    2012-10-15

    The corrosion behavior of gas metal arc welding (GMAW) regions has been studied using potentiodynamic polarization and polarization resistance (LPR) techniques. Experiments were conducted in hydrogen sulfide (H{sub 2}S)-containing brine and in H{sub 2}S-free brine. Welds were made on API 5L X52 steel. Due to differences in their microstructure, chemical composition and residual stress level, weld regions exhibited different responses under H{sub 2}S corrosion. Base metal exhibited the highest corrosion rate (CR) and the most cathodic corrosion potential. [Spanish] Se estudio el comportamiento ante la corrosion de las regiones de soldadura de un cordon realizado por arco metalico con gas (GMAW) sobre un acero grado API X52 mediante las tecnicas de polarizacion potencio dinamica y resistencia a la polarizacion (LPR). Los experimentos se realizaron utilizando salmuera con 300 ppm de acido sulfhidrico (H{sub 2}S) y salmuera libre de H{sub 2}S como electrolitos. Debido a las diferencias en su microestructura, composicion quimica y el nivel de esfuerzos residuales, las regiones de soldadura mostraron diferentes respuestas a la corrosion por H{sub 2}S. El metal base exhibio la velocidad de corrosion (VC) mas alta y el potencial de corrosion mas catodico.

  9. HI2: a two-degrees-of-freedom planar highly isotropic haptic interface for the desktop

    Science.gov (United States)

    Frisoli, Antonio; Prisco, Giuseppe M.; Salsedo, Fabio; Bergamasco, Massimo

    1999-11-01

    Haptic interfaces which fit on the desktop and provide a cursor control with 2D position convey additive feel sensations to the user in GUI and allow to enhance the efficiency of the human-computer interaction for both single user and collaborative applications. The merit of such devices is determined by the adaptability of the handle to different tasks/users, the ergonomics of the 2D workspace, the overall compactness of the device with respect to the usable workspace and the quality of the force feedback. A novel device has been designed along these guidelines. A new tendon-driven 5-bar mechanism is used to improve the isotropy of the kinematic performance over the workspace and the maximum generated force while reducing the device encumbrance. The present paper illustrates the kinematic and mechanical design of the device and reports the specifications achieved by the CAD model evaluation.

  10. High-performance image reconstruction in fluorescence tomography on desktop computers and graphics hardware.

    Science.gov (United States)

    Freiberger, Manuel; Egger, Herbert; Liebmann, Manfred; Scharfetter, Hermann

    2011-11-01

    Image reconstruction in fluorescence optical tomography is a three-dimensional nonlinear ill-posed problem governed by a system of partial differential equations. In this paper we demonstrate that a combination of state of the art numerical algorithms and a careful hardware optimized implementation allows to solve this large-scale inverse problem in a few seconds on standard desktop PCs with modern graphics hardware. In particular, we present methods to solve not only the forward but also the non-linear inverse problem by massively parallel programming on graphics processors. A comparison of optimized CPU and GPU implementations shows that the reconstruction can be accelerated by factors of about 15 through the use of the graphics hardware without compromising the accuracy in the reconstructed images.

  11. Using the rear projection of the Socibot Desktop robot for creation of applications with facial expressions

    Science.gov (United States)

    Gîlcă, G.; Bîzdoacă, N. G.; Diaconu, I.

    2016-08-01

    This article aims to implement some practical applications using the Socibot Desktop social robot. We mean to realize three applications: creating a speech sequence using the Kiosk menu of the browser interface, creating a program in the Virtual Robot browser interface and making a new guise to be loaded into the robot's memory in order to be projected onto it face. The first application is actually created in the Compose submenu that contains 5 file categories: audio, eyes, face, head, mood, this being helpful in the creation of the projected sequence. The second application is more complex, the completed program containing: audio files, speeches (can be created in over 20 languages), head movements, the robot's facial parameters function of each action units (AUs) of the facial muscles, its expressions and its line of sight. Last application aims to change the robot's appearance with the guise created by us. The guise was created in Adobe Photoshop and then loaded into the robot's memory.

  12. Assessing soil erosion risk using RUSLE through a GIS open source desktop and web application.

    Science.gov (United States)

    Duarte, L; Teodoro, A C; Gonçalves, J A; Soares, D; Cunha, M

    2016-06-01

    Soil erosion is a serious environmental problem. An estimation of the expected soil loss by water-caused erosion can be calculated considering the Revised Universal Soil Loss Equation (RUSLE). Geographical Information Systems (GIS) provide different tools to create categorical maps of soil erosion risk which help to study the risk assessment of soil loss. The objective of this study was to develop a GIS open source application (in QGIS), using the RUSLE methodology for estimating erosion rate at the watershed scale (desktop application) and provide the same application via web access (web application). The applications developed allow one to generate all the maps necessary to evaluate the soil erosion risk. Several libraries and algorithms from SEXTANTE were used to develop these applications. These applications were tested in Montalegre municipality (Portugal). The maps involved in RUSLE method-soil erosivity factor, soil erodibility factor, topographic factor, cover management factor, and support practices-were created. The estimated mean value of the soil loss obtained was 220 ton km(-2) year(-1) ranged from 0.27 to 1283 ton km(-2) year(-1). The results indicated that most of the study area (80 %) is characterized by very low soil erosion level (erosion was higher than 962 ton km(-2) year(-1). It was also concluded that areas with high slope values and bare soil are related with high level of erosion and the higher the P and C values, the higher the soil erosion percentage. The RUSLE web and the desktop application are freely available.

  13. Emission of particulate matter from a desktop three-dimensional (3D) printer.

    Science.gov (United States)

    Yi, Jinghai; LeBouf, Ryan F; Duling, Matthew G; Nurkiewicz, Timothy; Chen, Bean T; Schwegler-Berry, Diane; Virji, M Abbas; Stefaniak, Aleksandr B

    2016-01-01

    Desktop three-dimensional (3D) printers are becoming commonplace in business offices, public libraries, university labs and classrooms, and even private homes; however, these settings are generally not designed for exposure control. Prior experience with a variety of office equipment devices such as laser printers that emit ultrafine particles (UFP) suggests the need to characterize 3D printer emissions to enable reliable risk assessment. The aim of this study was to examine factors that influence particulate emissions from 3D printers and characterize their physical properties to inform risk assessment. Emissions were evaluated in a 0.5-m(3) chamber and in a small room (32.7 m(3)) using real-time instrumentation to measure particle number, size distribution, mass, and surface area. Factors evaluated included filament composition and color, as well as the manufacturer-provided printer emissions control technologies while printing an object. Filament type significantly influenced emissions, with acrylonitrile butadiene styrene (ABS) emitting larger particles than polylactic acid (PLA), which may have been the result of agglomeration. Geometric mean particle sizes and total particle (TP) number and mass emissions differed significantly among colors of a given filament type. Use of a cover on the printer reduced TP emissions by a factor of 2. Lung deposition calculations indicated a threefold higher PLA particle deposition in alveoli compared to ABS. Desktop 3D printers emit high levels of UFP, which are released into indoor environments where adequate ventilation may not be present to control emissions. Emissions in nonindustrial settings need to be reduced through the use of a hierarchy of controls, beginning with device design, followed by engineering controls (ventilation) and administrative controls such as choice of filament composition and color.

  14. Emission of particulate matter from a desktop three-dimensional (3D) printer

    Science.gov (United States)

    Yi, Jinghai; LeBouf, Ryan F.; Duling, Matthew G.; Nurkiewicz, Timothy; Chen, Bean T.; Schwegler-Berry, Diane; Virji, M. Abbas; Stefaniak, Aleksandr B.

    2016-01-01

    ABSTRACT Desktop three-dimensional (3D) printers are becoming commonplace in business offices, public libraries, university labs and classrooms, and even private homes; however, these settings are generally not designed for exposure control. Prior experience with a variety of office equipment devices such as laser printers that emit ultrafine particles (UFP) suggests the need to characterize 3D printer emissions to enable reliable risk assessment. The aim of this study was to examine factors that influence particulate emissions from 3D printers and characterize their physical properties to inform risk assessment. Emissions were evaluated in a 0.5-m3 chamber and in a small room (32.7 m3) using real-time instrumentation to measure particle number, size distribution, mass, and surface area. Factors evaluated included filament composition and color, as well as the manufacturer-provided printer emissions control technologies while printing an object. Filament type significantly influenced emissions, with acrylonitrile butadiene styrene (ABS) emitting larger particles than polylactic acid (PLA), which may have been the result of agglomeration. Geometric mean particle sizes and total particle (TP) number and mass emissions differed significantly among colors of a given filament type. Use of a cover on the printer reduced TP emissions by a factor of 2. Lung deposition calculations indicated a threefold higher PLA particle deposition in alveoli compared to ABS. Desktop 3D printers emit high levels of UFP, which are released into indoor environments where adequate ventilation may not be present to control emissions. Emissions in nonindustrial settings need to be reduced through the use of a hierarchy of controls, beginning with device design, followed by engineering controls (ventilation) and administrative controls such as choice of filament composition and color. PMID:27196745

  15. A Collaborative Digital Pathology System for Multi-Touch Mobile and Desktop Computing Platforms

    KAUST Repository

    Jeong, W.

    2013-06-13

    Collaborative slide image viewing systems are becoming increasingly important in pathology applications such as telepathology and E-learning. Despite rapid advances in computing and imaging technology, current digital pathology systems have limited performance with respect to remote viewing of whole slide images on desktop or mobile computing devices. In this paper we present a novel digital pathology client-server system that supports collaborative viewing of multi-plane whole slide images over standard networks using multi-touch-enabled clients. Our system is built upon a standard HTTP web server and a MySQL database to allow multiple clients to exchange image and metadata concurrently. We introduce a domain-specific image-stack compression method that leverages real-time hardware decoding on mobile devices. It adaptively encodes image stacks in a decorrelated colour space to achieve extremely low bitrates (0.8 bpp) with very low loss of image quality. We evaluate the image quality of our compression method and the performance of our system for diagnosis with an in-depth user study. Collaborative slide image viewing systems are becoming increasingly important in pathology applications such as telepathology and E-learning. Despite rapid advances in computing and imaging technology, current digital pathology systems have limited performance with respect to remote viewing of whole slide images on desktop or mobile computing devices. In this paper we present a novel digital pathology client-server systems that supports collaborative viewing of multi-plane whole slide images over standard networks using multi-touch enabled clients. Our system is built upon a standard HTTP web server and a MySQL database to allow multiple clients to exchange image and metadata concurrently. © 2013 The Eurographics Association and John Wiley & Sons Ltd.

  16. Additive Manufacturing by selective laser melting the realizer desktop machine and its application for the dental industry

    Science.gov (United States)

    Gebhardt, Andreas; Schmidt, Frank-Michael; Hötter, Jan-Steffen; Sokalla, Wolfgang; Sokalla, Patrick

    Additive Manufacturing of metal parts by Selective Laser Melting has become a powerful tool for the direct manufacturing of complex parts mainly for the aerospace and medical industry. With the introduction of its desktop machine, Realizer targeted the dental market. The contribution describes the special features of the machine, discusses details of the process and shows manufacturing results focused on metal dental devices.

  17. A Brief Discussion on Desktop Cloud Computing System%桌面云系统建设思路探讨

    Institute of Scientific and Technical Information of China (English)

    刘进; 卢楠; 温晓洁; 耿辉

    2013-01-01

      桌面云技术日趋成熟,已开始小规模部署来取代传统PC.本文简要介绍了桌面云技术的特点、架构,探讨了桌面云系统的建设模式和服务器、存储及网络三个关键设计点,为日后大规模建设桌面云系统,全面替代传统PC,降低运营、管理成本,提高企业信息安全提供借鉴.%The desktop cloud computing technology has become more and more mature, has begun a small-scale deployment to replace the traditional PC. This article briefly describes the characteristics of the desktop cloud computing technology architecture. The article explores three key design point of the desktop cloud system building mode and server, storage and network. The article provides a reference of large-scale construction of the desktop cloud computing system, a comprehensive alternative to the traditional PC, reduce operational management costs, improve enterprise information security in future.

  18. No effect of ambient odor on the affective appraisal of a desktop virtual environment with signs of disorder

    NARCIS (Netherlands)

    Toet, A.; Schaik, M.G. van; Theunissen, N.C.M.

    2013-01-01

    Background : Desktop virtual environments (VEs) are increasingly deployed to study the effects of environmental qualities and interventions on human behavior and safety related concerns in built environments. For these applications it is essential that users appraise the affective qualities of the V

  19. Reach a New Threshold of Freedom and Control with Dell's Flexible Computing Solution: On-Demand Desktop Streaming

    Science.gov (United States)

    Technology & Learning, 2008

    2008-01-01

    When it comes to IT, there has always been an important link between data center control and client flexibility. As computing power increases, so do the potentially crippling threats to security, productivity and financial stability. This article talks about Dell's On-Demand Desktop Streaming solution which is designed to centralize complete…

  20. Transcriptome analysis of the Asian honey bee Apis cerana cerana.

    Directory of Open Access Journals (Sweden)

    Zi Long Wang

    Full Text Available BACKGROUND: The Eastern hive honey bee, Apis cerana cerana is a native and widely bred honey bee species in China. Molecular biology research about this honey bee species is scarce, and genomic information for A. c. cerana is not currently available. Transcriptome and expression profiling data for this species are therefore important resources needed to better understand the biological mechanisms of A. c. cerana. In this study, we obtained the transcriptome information of A. c. cerana by RNA-sequencing and compared gene expression differences between queens and workers of A. c. cerana by digital gene expression (DGE analysis. RESULTS: Using high-throughput Illumina RNA sequencing we obtained 51,581,510 clean reads corresponding to 4.64 Gb total nucleotides from a single run. These reads were assembled into 46,999 unigenes with a mean length of 676 bp. Based on a sequence similarity search against the five public databases (NR, Swissport, GO, COG, KEGG with a cut-off E-value of 10(-5 using BLASTX, a total of 24,630 unigenes were annotated with gene descriptions, gene ontology terms, or metabolic pathways. Using these transcriptome data as references we analyzed the gene expression differences between the queens and workers of A. c. cerana using a tag-based digital gene expression method. We obtained 5.96 and 5.66 million clean tags from the queen and worker samples, respectively. A total of 414 genes were differentially expressed between them, with 189 up-regulated and 225 down-regulated in queens. CONCLUSIONS: Our transcriptome data provide a comprehensive sequence resource for future A. c. cerana study, establishing an important public information platform for functional genomic studies in A. c. cerana. Furthermore, the DGE data provide comprehensive gene expression information for the queens and workers, which will facilitate our understanding of the molecular mechanisms of the different physiological aspects of the two castes.

  1. Design and Implementation of desktop Application for distribution of Poor Households Using Flash (Actionscript 2.0 and visual basic (Case Of Study : Denpasar City

    Directory of Open Access Journals (Sweden)

    Indra Dwi Cahya Setyawan

    2015-10-01

    Full Text Available The application window poor households ( RTM Denpasar used to visualize web-based deployment RTM . In addition, this application also visualize health centers , rural credit institutions , and markets in the city of Denpasar . The application must be run with an internet connection . It discusses the studies on the implementation of flash , visual basic and xml to visualize the spread of the RTM in Denpasar . The test results of the application indicates that the flash and visual basic can be implemented to the spread of the RTM in Denpasar . So it becomes a desktop application that has some animation that is characteristic of the application. In addition it can serve as an xml file data storage so that applications are dynamic

  2. The Firegoose: two-way integration of diverse data from different bioinformatics web resources with desktop applications

    Directory of Open Access Journals (Sweden)

    Schmid Amy K

    2007-11-01

    Full Text Available Abstract Background Information resources on the World Wide Web play an indispensable role in modern biology. But integrating data from multiple sources is often encumbered by the need to reformat data files, convert between naming systems, or perform ongoing maintenance of local copies of public databases. Opportunities for new ways of combining and re-using data are arising as a result of the increasing use of web protocols to transmit structured data. Results The Firegoose, an extension to the Mozilla Firefox web browser, enables data transfer between web sites and desktop tools. As a component of the Gaggle integration framework, Firegoose can also exchange data with Cytoscape, the R statistical package, Multiexperiment Viewer (MeV, and several other popular desktop software tools. Firegoose adds the capability to easily use local data to query KEGG, EMBL STRING, DAVID, and other widely-used bioinformatics web sites. Query results from these web sites can be transferred to desktop tools for further analysis with a few clicks. Firegoose acquires data from the web by screen scraping, microformats, embedded XML, or web services. We define a microformat, which allows structured information compatible with the Gaggle to be embedded in HTML documents. We demonstrate the capabilities of this software by performing an analysis of the genes activated in the microbe Halobacterium salinarum NRC-1 in response to anaerobic environments. Starting with microarray data, we explore functions of differentially expressed genes by combining data from several public web resources and construct an integrated view of the cellular processes involved. Conclusion The Firegoose incorporates Mozilla Firefox into the Gaggle environment and enables interactive sharing of data between diverse web resources and desktop software tools without maintaining local copies. Additional web sites can be incorporated easily into the framework using the scripting platform of the

  3. Sperm use economy of honeybee (Apis mellifera) queens

    DEFF Research Database (Denmark)

    Baer, Boris; Collins, Jason; Maalaps, Kristiina;

    2016-01-01

    the fecundity and longevity of queens and therefore colony fitness. We quantified the number of sperm that honeybee (Apis mellifera) queens use to fertilize eggs. We examined sperm use in naturally mated queens of different ages and in queens artificially inseminated with different volumes of semen. We found...

  4. Standard methods for research on apis mellifera gut symbionts

    Science.gov (United States)

    Gut microbes can play an important role in digestion, disease resistance, and the general health of animals, but little is known about the biology of gut symbionts in Apis mellifera. This paper is part of a series on honey bee research methods, providing protocols for studying gut symbionts. We desc...

  5. Fertile diploid drones in africanized honeybees, Apis mellifera adansonii.

    Science.gov (United States)

    Chaud-Netto, J

    1977-02-15

    59 diploid drones of Apis mellifera adansonii, 12-37 days old, were tested for the presence of semen after provoked ejaculation; 13 drones ejaculated semen enough to be used in an instrumental insemination, but only three on them (5%) furnished 1 mm3 of semen. The problems referring to the attainment of descendants from the 2n drones are briefly discussed.

  6. PrismTech Data Distribution Service Java API Evaluation

    Science.gov (United States)

    Riggs, Cortney

    2008-01-01

    My internship duties with Launch Control Systems required me to start performance testing of an Object Management Group's (OMG) Data Distribution Service (DDS) specification implementation by PrismTech Limited through the Java programming language application programming interface (API). DDS is a networking middleware for Real-Time Data Distribution. The performance testing involves latency, redundant publishers, extended duration, redundant failover, and read performance. Time constraints allowed only for a data throughput test. I have designed the testing applications to perform all performance tests when time is allowed. Performance evaluation data such as megabits per second and central processing unit (CPU) time consumption were not easily attainable through the Java programming language; they required new methods and classes created in the test applications. Evaluation of this product showed the rate that data can be sent across the network. Performance rates are better on Linux platforms than AIX and Sun platforms. Compared to previous C++ programming language API, the performance evaluation also shows the language differences for the implementation. The Java API of the DDS has a lower throughput performance than the C++ API.

  7. The Automatic Start Method of Application Program Using API

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    This paper introduces on a method about the au-tomactic start of application program. Through defining Registryby API function, the automatic start of specified application pro-gram is fulfilled when Windows98 is taking action. It gives facil-ities to many computer application works.

  8. Modelling the subgenual organ of the honeybee, Apis mellifera

    DEFF Research Database (Denmark)

    Storm, Jesper; Kilpinen, Ole

    1998-01-01

    In a recent study on the honeybee (Apis mellifera), the subgenual organ was observed moving inside the leg during sinusoidal vibrations of the leg (Kilpinen and Storm 1997). The subgenual organ of the honeybee is suspended in a haemolymph channel in the tibia of each leg. When the leg accelerates...

  9. Physicochemical composition of Apis mellifera honey samples from São Paulo State, Brazil

    Directory of Open Access Journals (Sweden)

    Luís Carlos Marchini

    2007-01-01

    Full Text Available This research, developed with Apis mellifera honey samples from producers of São Paulo State, Brazil, has the objective of verifying how eucalyptus, wild flower, and orange honey samples would be clustered, based on physicochemical characteristics. All the orange honey samples and some wild flower ones formed distinct groups, thus confirming that the floral source interferes with honey characteristics. Eucalyptus and some of the wild flower honey samples were clustered together because of the great floral source variation in the latter ones. The characteristics that influence sample clustering are acidity and electric conductivity on the X axis, and total sugars and pH on the Y axis.

  10. Detection of Illicit Drugs by Trained Honeybees (Apis mellifera.

    Directory of Open Access Journals (Sweden)

    Matthias Schott

    Full Text Available Illegal drugs exacerbate global social challenges such as substance addiction, mental health issues and violent crime. Police and customs officials often rely on specially-trained sniffer dogs, which act as sensitive biological detectors to find concealed illegal drugs. However, the dog "alert" is no longer sufficient evidence to allow a search without a warrant or additional probable cause because cannabis has been legalized in two US states and is decriminalized in many others. Retraining dogs to recognize a narrower spectrum of drugs is difficult and training new dogs is time consuming, yet there are no analytical devices with the portability and sensitivity necessary to detect substance-specific chemical signatures. This means there is currently no substitute for sniffer dogs. Here we describe an insect screening procedure showing that the western honeybee (Apis mellifera can sense volatiles associated with pure samples of heroin and cocaine. We developed a portable electroantennographic device for the on-site measurement of volatile perception by these insects, and found a positive correlation between honeybee antennal responses and the concentration of specific drugs in test samples. Furthermore, we tested the ability of honeybees to learn the scent of heroin and trained them to show a reliable behavioral response in the presence of a highly-diluted scent of pure heroin. Trained honeybees could therefore be used to complement or replace the role of sniffer dogs as part of an automated drug detection system. Insects are highly sensitive to volatile compounds and provide an untapped resource for the development of biosensors. Automated conditioning as presented in this study could be developed as a platform for the practical detection of illicit drugs using insect-based sensors.

  11. Acaricide, fungicide and drug interactions in honey bees (Apis mellifera.

    Directory of Open Access Journals (Sweden)

    Reed M Johnson

    Full Text Available BACKGROUND: Chemical analysis shows that honey bees (Apis mellifera and hive products contain many pesticides derived from various sources. The most abundant pesticides are acaricides applied by beekeepers to control Varroa destructor. Beekeepers also apply antimicrobial drugs to control bacterial and microsporidial diseases. Fungicides may enter the hive when applied to nearby flowering crops. Acaricides, antimicrobial drugs and fungicides are not highly toxic to bees alone, but in combination there is potential for heightened toxicity due to interactive effects. METHODOLOGY/PRINCIPAL FINDINGS: Laboratory bioassays based on mortality rates in adult worker bees demonstrated interactive effects among acaricides, as well as between acaricides and antimicrobial drugs and between acaricides and fungicides. Toxicity of the acaricide tau-fluvalinate increased in combination with other acaricides and most other compounds tested (15 of 17 while amitraz toxicity was mostly unchanged (1 of 15. The sterol biosynthesis inhibiting (SBI fungicide prochloraz elevated the toxicity of the acaricides tau-fluvalinate, coumaphos and fenpyroximate, likely through inhibition of detoxicative cytochrome P450 monooxygenase activity. Four other SBI fungicides increased the toxicity of tau-fluvalinate in a dose-dependent manner, although possible evidence of P450 induction was observed at the lowest fungicide doses. Non-transitive interactions between some acaricides were observed. Sublethal amitraz pre-treatment increased the toxicity of the three P450-detoxified acaricides, but amitraz toxicity was not changed by sublethal treatment with the same three acaricides. A two-fold change in the toxicity of tau-fluvalinate was observed between years, suggesting a possible change in the genetic composition of the bees tested. CONCLUSIONS/SIGNIFICANCE: Interactions with acaricides in honey bees are similar to drug interactions in other animals in that P450-mediated detoxication

  12. Sensor Observation Service API for Providing Gridded Climate Data to Agricultural Applications

    Directory of Open Access Journals (Sweden)

    Rassarin Chinnachodteeranun

    2016-08-01

    Full Text Available We developed a mechanism for seamlessly providing weather data and long-term historical climate data from a gridded data source through an international standard web API, which was the Sensor Observation Service (SOS defined by the Open Geospatial Consortium (OGC. The National Agriculture and Food Research Organization (NARO Japan has been providing gridded climate data consisting of nine daily meteorological variables, which are average, minimum, maximum of air temperature, relative humidity, sunshine duration, solar radiant exposure, downward longwave radiation, precipitation and wind speed for 35 years covering Japan. The gridded data structure is quite useful for spatial analysis, such as developing crop suitability maps and monitoring regional crop development. Individual farmers, however, make decisions using historical climate information and forecasts for an incoming cropping season of their farms. In this regard, climate data at a point-based structure are convenient for application development to support farmers’ decisions. Through the proposed mechanism in this paper, the agricultural applications and analysis can request point-based climate data from a gridded data source through the standard API with no need to deal with the complicated hierarchical data structure of the gridded climate data source. Clients can easily obtain data and metadata by only accessing the service endpoint. The mechanism also provides several web bindings and data encodings for the clients’ convenience. Caching, including the pre-caching mechanism, was developed and evaluated to secure an effective response time. The mechanism enhances the accessibility and usability of the gridded weather data source, as well as SOS API for agricultural applications.

  13. Accessing the SEED Genome Databases via Web Services API: Tools for Programmers

    Directory of Open Access Journals (Sweden)

    Vonstein Veronika

    2010-06-01

    Full Text Available Abstract Background The SEED integrates many publicly available genome sequences into a single resource. The database contains accurate and up-to-date annotations based on the subsystems concept that leverages clustering between genomes and other clues to accurately and efficiently annotate microbial genomes. The backend is used as the foundation for many genome annotation tools, such as the Rapid Annotation using Subsystems Technology (RAST server for whole genome annotation, the metagenomics RAST server for random community genome annotations, and the annotation clearinghouse for exchanging annotations from different resources. In addition to a web user interface, the SEED also provides Web services based API for programmatic access to the data in the SEED, allowing the development of third-party tools and mash-ups. Results The currently exposed Web services encompass over forty different methods for accessing data related to microbial genome annotations. The Web services provide comprehensive access to the database back end, allowing any programmer access to the most consistent and accurate genome annotations available. The Web services are deployed using a platform independent service-oriented approach that allows the user to choose the most suitable programming platform for their application. Example code demonstrate that Web services can be used to access the SEED using common bioinformatics programming languages such as Perl, Python, and Java. Conclusions We present a novel approach to access the SEED database. Using Web services, a robust API for access to genomics data is provided, without requiring large volume downloads all at once. The API ensures timely access to the most current datasets available, including the new genomes as soon as they come online.

  14. EXPERIENCE API – NEW STANDARD OF E-LEARNING SOFTWARE AND EXAMPLES OF ITS PRACTICAL USE

    Directory of Open Access Journals (Sweden)

    Oleksandr A. Shcherbyna

    2016-07-01

    Full Text Available The purpose of the article is to analyze features of the new standard of e-learning software - Experience API (xAPI, previously also known as the Tin Can API. The standard defines a way of interaction between xAPI-clients – software which students work with while e-learning process, and xAPI-servers – Learning Record Stores (LRS, which store data about their results. Standard also defines LRS data representation format and a way of data transfers between LRS, which makes it possible to combine several LRS into distributed database that could accumulate information about people training in formal, non-formal and informal education throughout life. The article contains review of available xAPI-clients, xAPI-servers, and the results of their testing, which prove the possibility of their usage in our educational institutions.

  15. Host Specificity in the Honeybee Parasitic Mite, Varroa spp. in Apis mellifera and Apis cerana.

    Directory of Open Access Journals (Sweden)

    Alexis L Beaurepaire

    Full Text Available The ectoparasitic mite Varroa destructor is a major global threat to the Western honeybee Apis mellifera. This mite was originally a parasite of A. cerana in Asia but managed to spill over into colonies of A. mellifera which had been introduced to this continent for honey production. To date, only two almost clonal types of V. destructor from Korea and Japan have been detected in A. mellifera colonies. However, since both A. mellifera and A. cerana colonies are kept in close proximity throughout Asia, not only new spill overs but also spill backs of highly virulent types may be possible, with unpredictable consequences for both honeybee species. We studied the dispersal and hybridisation potential of Varroa from sympatric colonies of the two hosts in Northern Vietnam and the Philippines using mitochondrial and microsatellite DNA markers. We found a very distinct mtDNA haplotype equally invading both A. mellifera and A. cerana in the Philippines. In contrast, we observed a complete reproductive isolation of various Vietnamese Varroa populations in A. mellifera and A. cerana colonies even if kept in the same apiaries. In light of this variance in host specificity, the adaptation of the mite to its hosts seems to have generated much more genetic diversity than previously recognised and the Varroa species complex may include substantial cryptic speciation.

  16. Changes in Alternative Splicing in Apis Mellifera Bees Fed Apis Cerana Royal Jelly

    Directory of Open Access Journals (Sweden)

    Shi Yuan Yuan

    2014-12-01

    Full Text Available The Western honey bee (Apis mellifera is a social insect characterized by caste differentiation in which the queen bee and worker bees display marked differences in morphology, behavior, reproduction, and longevity despite their identical genomes. The main causative factor in caste differentiation is the food fed to queen larvae, termed royal jelly (RJ. Alternative splicing (AS is an important RNA-mediated post-transcriptional process in eukaryotes. Here we report AS changes in A. mellifera after being fed either A. mellifera RJ or A. cerana RJ. The results demonstrated that the RJ type affected 4 types of AS in adult A. mellifera: exon skipping, intron retention, alternative 5’ splice sites, and alternative 3’splice sites. After feeding with A. cerana RJ, AS occurred in many genes in adult A. mellifera that encode proteins involved in development, growth, the tricarboxylic acid cycle, and substance metabolism. This study provides the first evidence that heterospecific RJ can influence the AS of many genes related to honey bee development and growth.

  17. Host Specificity in the Honeybee Parasitic Mite, Varroa spp. in Apis mellifera and Apis cerana.

    Science.gov (United States)

    Beaurepaire, Alexis L; Truong, Tuan A; Fajardo, Alejandro C; Dinh, Tam Q; Cervancia, Cleofas; Moritz, Robin F A

    2015-01-01

    The ectoparasitic mite Varroa destructor is a major global threat to the Western honeybee Apis mellifera. This mite was originally a parasite of A. cerana in Asia but managed to spill over into colonies of A. mellifera which had been introduced to this continent for honey production. To date, only two almost clonal types of V. destructor from Korea and Japan have been detected in A. mellifera colonies. However, since both A. mellifera and A. cerana colonies are kept in close proximity throughout Asia, not only new spill overs but also spill backs of highly virulent types may be possible, with unpredictable consequences for both honeybee species. We studied the dispersal and hybridisation potential of Varroa from sympatric colonies of the two hosts in Northern Vietnam and the Philippines using mitochondrial and microsatellite DNA markers. We found a very distinct mtDNA haplotype equally invading both A. mellifera and A. cerana in the Philippines. In contrast, we observed a complete reproductive isolation of various Vietnamese Varroa populations in A. mellifera and A. cerana colonies even if kept in the same apiaries. In light of this variance in host specificity, the adaptation of the mite to its hosts seems to have generated much more genetic diversity than previously recognised and the Varroa species complex may include substantial cryptic speciation.

  18. [New Approach to the Mitotype Classification in Black Honeybee Apis mellifera mellifera and Iberian Honeybee Apis mellifera iberiensis].

    Science.gov (United States)

    Ilyasov, R A; Poskryakov, A V; Petukhov, A V; Nikolenko, A G

    2016-03-01

    The black honeybee Apis mellifera mellifera L. is today the only subspecies of honeybee which is suitable for commercial breeding in the climatic conditions of Northern Europe with long cold winters. The main problem of the black honeybee in Russia and European countries is the preservation of the indigenous gene pool purity, which is lost as a result of hybridization with subspecies, A. m. caucasica, A. m. carnica, A. m. carpatica, and A. m. armeniaca, introduced from southern regions. Genetic identification of the subspecies will reduce the extent of hybridization and provide the gene pool conservation of the black honeybee. Modern classification of the honeybee mitotypes is mainly based on the combined use ofthe DraI restriction endonuclease recognition site polymorphism and sequence polymorphism of the mtDNA COI-COII region. We performed a comparative analysis of the mtDNA COI-COII region sequence polymorphism in the honeybees ofthe evolutionary lineage M from Ural and West European populations of black honeybee A. m. mellifera and Spanish bee A. m. iberiensis. A new approach to the classification of the honeybee M mitotypes was suggested. Using this approach and on the basis of the seven most informative SNPs of the mtDNA COI-COII region, eight honeybee mitotype groups were identified. In addition, it is suggested that this approach will simplify the previously proposed complicated mitotype classification and will make it possible to assess the level of the mitotype diversity and to identify the mitotypes that are the most valuable for the honeybee breeding and rearing.

  19. Linux用户空间加/解密API的设计与实现%DESIGN AND IMPLEMENTATION OF LINUX USER-SPACE CRYPTOGRAPHIC API

    Institute of Scientific and Technical Information of China (English)

    李石磊; 闫宏印

    2013-01-01

    Development of the unified Crypto API interface for user-space applications is one of future design goals for Linux kernel developers. In this paper, by taking IPsec VPN gateway agent system as the application model, and using Linux system call interception and loadable kernel module technique, we study the development process and designing method of the system call-based user-space cryptographic API. Meanwhile, by comparison with the Netlink-based API, it is found that this API interface is more flexibility in design and can be customised as well. Taking the application model as the background, this API interface is tested its performance of practical use. Result shows that the use of this system call-based API can improve overall system operation performance and the system stability.%开发标准的用户空间Crypto API接口是Linux内核开发者未来开发目标之一.以IPsec VPN网关代理系统为应用模型,使用动态模块加载机制和系统调用劫持技术,对基于系统调用的用户空间加/解密API的开发流程和设计方法进行研究.通过与基于Netlink用户空间加/解密API进行对比,展示了该API接口的设计灵活性和可定制性.并以应用模型为背景,对该API接口的实际使用性能进行测试.结果表明,使用该API接口,可以提高系统的整体运行效率,也可以提高系统的稳定性.

  20. Determination of API content in a pilot-scale blending by near-infrared spectroscopy as a first step method to process line implementation.

    Science.gov (United States)

    Jamrógiewicz, Marzena; Cal, Krzysztof; Gruszecka, Magdalena; Ciesielski, Aleksander

    2013-01-01

    Near infrared (NIR) spectroscopy was used for estimation of powder blend homogeneity and manufacturing control of a medicinal product powder mixture containing active pharmaceutical ingredient (API). Aiming at initiating a Process Analytical Technology (PAT) activity, the first step was a stationary mode at-line evaluation. In this, the content of pharmaceutical active compound in the powder mixtures intended to the direct tabletting was estimated based on recorded NIR spectra. Five formulations containing different quantities of API were prepared and analyzed also by a reference method--UV-Vis spectroscopy. A chemometric model was developed for calculation of the API amount in the mixtures. The Principal Component Regression (PCR) and Partial Least Squares (PLS) algorithms were used to obtain a model useful in further implementation for the PAT recommendations, into in-line blending control.

  1. On the virtual desktop in the College of Architecture and applications%浅谈虚拟化桌面在高校的架构和应用

    Institute of Scientific and Technical Information of China (English)

    刘剑锋

    2012-01-01

    在云计算时代,虚拟化桌面是必然趋势。本文介绍了虚拟化桌面的相关技术。分析了虚拟化桌面应用于高校的益处并比较两种虚拟化方案的利弊。%In the era of cloud computing,virtualization desktop is an inevitable trend.This paper introduces a desktop virtualization technology.Analysis of the pros and cons of the benefits of virtualized desktops used in colleges and universities and compare the two virtualization programs.

  2. Quantitative analysis of active pharmaceutical ingredients (APIs) using a potentiometric electronic tongue in a SIA flow system

    OpenAIRE

    2016-01-01

    An advanced potentiometric electronic tongue and Sequential Injection Analysis (SIA) measurement system was applied for the quantitative analysis of mixtures containing three active pharmaceutical ingredients (APIs): acetaminophen, ascorbic acid and acetylsalicylic acid, in the presence of various amounts of caffeine as interferent. The flow-through sensor array was composed of miniaturized classical ion-selective electrodes based on plasticized PVC membranes containing only ion exchangers. P...

  3. Application and API for Real-time Visualization of Ground-motions and Tsunami

    Science.gov (United States)

    Aoi, S.; Kunugi, T.; Suzuki, W.; Kubo, T.; Nakamura, H.; Azuma, H.; Fujiwara, H.

    2015-12-01

    Due to the recent progress of seismograph and communication environment, real-time and continuous ground-motion observation becomes technically and economically feasible. K-NET and KiK-net, which are nationwide strong motion networks operated by NIED, cover all Japan by about 1750 stations in total. More than half of the stations transmit the ground-motion indexes and/or waveform data in every second. Traditionally, strong-motion data were recorded by event-triggering based instruments with non-continues telephone line which is connected only after an earthquake. Though the data from such networks mainly contribute to preparations for future earthquakes, huge amount of real-time data from dense network are expected to directly contribute to the mitigation of ongoing earthquake disasters through, e.g., automatic shutdown plants and helping decision-making for initial response. By generating the distribution map of these indexes and uploading them to the website, we implemented the real-time ground motion monitoring system, Kyoshin (strong-motion in Japanese) monitor. This web service (www.kyoshin.bosai.go.jp) started in 2008 and anyone can grasp the current ground motions of Japan. Though this service provides only ground-motion map in GIF format, to take full advantage of real-time strong-motion data to mitigate the ongoing disasters, digital data are important. We have developed a WebAPI to provide real-time data and related information such as ground motions (5 km-mesh) and arrival times estimated from EEW (earthquake early warning). All response data from this WebAPI are in JSON format and are easy to parse. We also developed Kyoshin monitor application for smartphone, 'Kmoni view' using the API. In this application, ground motions estimated from EEW are overlapped on the map with the observed one-second-interval indexes. The application can playback previous earthquakes for demonstration or disaster drill. In mobile environment, data traffic and battery are

  4. VIPERdb2: an enhanced and web API enabled relational database for structural virology.

    Science.gov (United States)

    Carrillo-Tripp, Mauricio; Shepherd, Craig M; Borelli, Ian A; Venkataraman, Sangita; Lander, Gabriel; Natarajan, Padmaja; Johnson, John E; Brooks, Charles L; Reddy, Vijay S

    2009-01-01

    VIPERdb (http://viperdb.scripps.edu) is a relational database and a web portal for icosahedral virus capsid structures. Our aim is to provide a comprehensive resource specific to the needs of the virology community, with an emphasis on the description and comparison of derived data from structural and computational analyses of the virus capsids. In the current release, VIPERdb(2), we implemented a useful and novel method to represent capsid protein residues in the icosahedral asymmetric unit (IAU) using azimuthal polar orthographic projections, otherwise known as Phi-Psi (Phi-Psi) diagrams. In conjunction with a new Application Programming Interface (API), these diagrams can be used as a dynamic interface to the database to map residues (categorized as surface, interface and core residues) and identify family wide conserved residues including hotspots at the interfaces. Additionally, we enhanced the interactivity with the database by interfacing with web-based tools. In particular, the applications Jmol and STRAP were implemented to visualize and interact with the virus molecular structures and provide sequence-structure alignment capabilities. Together with extended curation practices that maintain data uniformity, a relational database implementation based on a schema for macromolecular structures and the APIs provided will greatly enhance the ability to do structural bioinformatics analysis of virus capsids.

  5. Infra-population and -community dynamics of the parasites Nosema apis and Nosema ceranae, and consequences for honey bee (Apis mellifera hosts.

    Directory of Open Access Journals (Sweden)

    Geoffrey R Williams

    Full Text Available Nosema spp. fungal gut parasites are among myriad possible explanations for contemporary increased mortality of western honey bees (Apis mellifera, hereafter honey bee in many regions of the world. Invasive Nosema ceranae is particularly worrisome because some evidence suggests it has greater virulence than its congener N. apis. N. ceranae appears to have recently switched hosts from Asian honey bees (Apis cerana and now has a nearly global distribution in honey bees, apparently displacing N. apis. We examined parasite reproduction and effects of N. apis, N. ceranae, and mixed Nosema infections on honey bee hosts in laboratory experiments. Both infection intensity and honey bee mortality were significantly greater for N. ceranae than for N. apis or mixed infections; mixed infection resulted in mortality similar to N. apis parasitism and reduced spore intensity, possibly due to inter-specific competition. This is the first long-term laboratory study to demonstrate lethal consequences of N. apis and N. ceranae and mixed Nosema parasitism in honey bees, and suggests that differences in reproduction and intra-host competition may explain apparent heterogeneous exclusion of the historic parasite by the invasive species.

  6. Haptic devices and objects, robots and mannequin simulation in a CAD-CAM software: eM-Virtual Desktop

    CERN Document Server

    Chablat, Damien; Hoessler, Bernard; Guibert, Matthieu

    2011-01-01

    This paper presents the development of a new software in order to manage objects, robots and mannequins in using the possibilities given by the haptic feedback of the Phantom desktop devices. The haptic device provides 6 positional degrees of freedom sensing but three degrees force feedback. This software called eM-Virtual Desktop is integrated in the Tecnomatix's solution called eM-Workplace. The eM-Workplace provides powerful solutions for planning and designing of complex assembly facilities, lines and workplaces. In the digital mockup context, the haptic interfaces can be used to reduce the development cycle of products. Three different loops are used to manage the graphic, the collision detection and the haptic feedback according to theirs own frequencies. The developed software is currently tested in industrial context by a European automotive constructor.

  7. Applications of Desktop Cloud Technology in Hospitals%桌面云在医疗行业中的应用

    Institute of Scientific and Technical Information of China (English)

    杨君; 郝泽余

    2016-01-01

    Facing increasing number of PC, the aging of terminal PC, the decreasing of system speed and the complicated operational works, the technology of desktop cloud brings a new situation for digital hospital building. In this paper, applications and features of desktop cloud technology in hospitals were discussed.%面对医院信息化建设过程中PC的数量的增加、PC终端的老化、系统运行速度的下降、运维工作的复杂化等问题,桌面云技术为数字化医院建设带来全新的局面,本文探讨了桌面云技术在医院的实施应用及特点。

  8. A Unified Algorithm for Virtual Desktops Placement in Distributed Cloud Computing

    Directory of Open Access Journals (Sweden)

    Jiangtao Zhang

    2016-01-01

    Full Text Available Distributed cloud has been widely adopted to support service requests from dispersed regions, especially for large enterprise which requests virtual desktops for multiple geodistributed branch companies. The cloud service provider (CSP aims to deliver satisfactory services at the least cost. CSP selects proper data centers (DCs closer to the branch companies so as to shorten the response time to user request. At the same time, it also strives to cut cost considering both DC level and server level. At DC level, the expensive long distance inter-DC bandwidth consumption should be reduced and lower electricity price is sought. Inside each tree-like DC, servers are trying to be used as little as possible so as to save equipment cost and power. In nature, there is a noncooperative relation between the DC level and server level in the selection. To attain these objectives and capture the noncooperative relation, multiobjective bilevel programming is used to formulate the problem. Then a unified genetic algorithm is proposed to solve the problem which realizes the selection of DC and server simultaneously. The extensive simulation shows that the proposed algorithm outperforms baseline algorithm in both quality of service guaranteeing and cost saving.

  9. Effects of Local-Lag Mechanism on Task Performance in a Desktop CVE System

    Institute of Scientific and Technical Information of China (English)

    Hong Chen; Ling Chen; Gen-Cai Chen

    2005-01-01

    Consistency maintenance is a kernel problem in Collaborative Virtual Environment (CVE) research. The approaches used in Networked Virtual Environments (e.g., DR algorithm) could not be used in CVEs, for they could not prevent short-term inconsistency. Therefore, local-lag mechanism has been proposed to eliminate short-term inconsistency in CVEs. Choosing a proper lag value is a key problem in local-lag mechanism. This paper studied the effects of lag value (0ms-900ms) on task performance in a desktop CVE system. Experimental results indicate that the effect of lag value on task performance is not linear. The effect could be separated into four segments by three dividing points: 150ms, 300ms and 600ms. Lag has no effect on task performance while ranging from 0ms to 150ms. From 150ms to 300ms, lag slightly affects task performance. Lag deteriorates task performance seriously while ranging from 300ms to 600ms. When lag is longer than 600ms, the task cannot be accomplished sometimes.

  10. A desktop system of virtual morphometric globes for Mars and the Moon

    Science.gov (United States)

    Florinsky, I. V.; Filippov, S. V.

    2017-03-01

    Global morphometric models can be useful for earth and planetary studies. Virtual globes - programs implementing interactive three-dimensional (3D) models of planets - are increasingly used in geo- and planetary sciences. We describe the development of a desktop system of virtual morphometric globes for Mars and the Moon. As the initial data, we used 15'-gridded global digital elevation models (DEMs) extracted from the Mars Orbiter Laser Altimeter (MOLA) and the Lunar Orbiter Laser Altimeter (LOLA) gridded archives. For two celestial bodies, we derived global digital models of several morphometric attributes, such as horizontal curvature, vertical curvature, minimal curvature, maximal curvature, and catchment area. To develop the system, we used Blender, the free open-source software for 3D modeling and visualization. First, a 3D sphere model was generated. Second, the global morphometric maps were imposed to the sphere surface as textures. Finally, the real-time 3D graphics Blender engine was used to implement rotation and zooming of the globes. The testing of the developed system demonstrated its good performance. Morphometric globes clearly represent peculiarities of planetary topography, according to the physical and mathematical sense of a particular morphometric variable.

  11. AS COMPOSIÇÕES DA ESCUTA E A INTERNET: OS DJ'S DE DESKTOP

    Directory of Open Access Journals (Sweden)

    Rodrigo Fonseca e Rodrigues

    2006-12-01

    Full Text Available O texto aborda questões emergentes das ocasiões de experiência que, ativadas pelo uso idiossincrático das máquinas em rede, passam a contagiar circunstâncias e práticas genuínas de composição musical, bem como de outras disposições da escuta. Isto se passa quando os "dj's produtores de desktop" remodulam forças latentes nos enunciados musicais da cultura corporativa para revelarem, a partir da prática do remix, outros eventos, instaurando regimes singulares para a sensação. Seria preciso pensar tais poéticas da escuta em rede como implicações conjuntas de conexões não apenas de materiais musicais, mas também de universos incorporais, de forças insonoras, amparando-se, para tanto, nas direções conceituais deleuzianas acerca das questões do virtual e do acontecimento na sensação musical.

  12. Desktop Software for Patch-Clamp Raw Binary Data Conversion and Preprocessing

    Directory of Open Access Journals (Sweden)

    Ning Zhang

    2011-01-01

    Full Text Available Since raw data recorded by patch-clamp systems are always stored in binary format, electrophysiologists may experience difficulties with patch clamp data preprocessing especially when they want to analyze by custom-designed algorithms. In this study, we present desktop software, called PCDReader, which could be an effective and convenient solution for patch clamp data preprocessing for daily laboratory use. We designed a novel class module, called clsPulseData, to directly read the raw data along with the parameters recorded from HEKA instruments without any other program support. By a graphical user interface, raw binary data files can be converted into several kinds of ASCII text files for further analysis, with several preprocessing options. And the parameters can also be viewed, modified and exported into ASCII files by a user-friendly Explorer style window. The real-time data loading technique and optimized memory management programming makes PCDReader a fast and efficient tool. The compiled software along with the source code of the clsPulseData class module is freely available to academic and nonprofit users.

  13. Deep Unsupervised Learning on a Desktop PC: A Primer for Cognitive Scientists.

    Science.gov (United States)

    Testolin, Alberto; Stoianov, Ivilin; De Filippo De Grazia, Michele; Zorzi, Marco

    2013-01-01

    Deep belief networks hold great promise for the simulation of human cognition because they show how structured and abstract representations may emerge from probabilistic unsupervised learning. These networks build a hierarchy of progressively more complex distributed representations of the sensory data by fitting a hierarchical generative model. However, learning in deep networks typically requires big datasets and it can involve millions of connection weights, which implies that simulations on standard computers are unfeasible. Developing realistic, medium-to-large-scale learning models of cognition would therefore seem to require expertise in programing parallel-computing hardware, and this might explain why the use of this promising approach is still largely confined to the machine learning community. Here we show how simulations of deep unsupervised learning can be easily performed on a desktop PC by exploiting the processors of low cost graphic cards (graphic processor units) without any specific programing effort, thanks to the use of high-level programming routines (available in MATLAB or Python). We also show that even an entry-level graphic card can outperform a small high-performance computing cluster in terms of learning time and with no loss of learning quality. We therefore conclude that graphic card implementations pave the way for a widespread use of deep learning among cognitive scientists for modeling cognition and behavior.

  14. VRLane: a desktop virtual safety management program for underground coal mine

    Science.gov (United States)

    Li, Mei; Chen, Jingzhu; Xiong, Wei; Zhang, Pengpeng; Wu, Daozheng

    2008-10-01

    VR technologies, which generate immersive, interactive, and three-dimensional (3D) environments, are seldom applied to coal mine safety work management. In this paper, a new method that combined the VR technologies with underground mine safety management system was explored. A desktop virtual safety management program for underground coal mine, called VRLane, was developed. The paper mainly concerned about the current research advance in VR, system design, key techniques and system application. Two important techniques were introduced in the paper. Firstly, an algorithm was designed and implemented, with which the 3D laneway models and equipment models can be built on the basis of the latest mine 2D drawings automatically, whereas common VR programs established 3D environment by using 3DS Max or the other 3D modeling software packages with which laneway models were built manually and laboriously. Secondly, VRLane realized system integration with underground industrial automation. VRLane not only described a realistic 3D laneway environment, but also described the status of the coal mining, with functions of displaying the run states and related parameters of equipment, per-alarming the abnormal mining events, and animating mine cars, mine workers, or long-wall shearers. The system, with advantages of cheap, dynamic, easy to maintenance, provided a useful tool for safety production management in coal mine.

  15. Prototype Implementation of Web and Desktop Applications for ALMA Science Verification Data and the Lessons Learned

    CERN Document Server

    Eguchi, Satoshi; Shirasaki, Yuji; Komiya, Yutaka; Kosugi, George; Ohishi, Masatoshi; Mizumoto, Yoshihiko

    2012-01-01

    ALMA is estimated to generate TB scale data during only one observation; astronomers manage to identify which part of the data they are really interested in. Now we have been developing new GUI software for this purpose utilizing the VO interface: ALMA Web Quick Look System (ALMAWebQL) and ALMA Desktop Application (Vissage). The former is written in JavaScript and HTML5 generated from Java codes by Google Web Toolkit, and the latter is in pure Java. An essential point of our approach is how to reduce network traffic: we prepare, in advance, "compressed" FITS files of 2x2x1 (horizontal, vertical, and spectral directions, respectively) binning, 2x2x2 binning, 4x4x2 binning data, and so on. These files are hidden from users, and Web QL automatically choose proper one by each user operation. Through this work, we find that network traffic in our system is still a bottleneck towards TB scale data distribution. Hence we have to develop alternative data containers for much faster data processing. In this paper, I in...

  16. Deep unsupervised learning on a desktop PC: A primer for cognitive scientists

    Directory of Open Access Journals (Sweden)

    Alberto eTestolin

    2013-05-01

    Full Text Available Deep belief networks hold great promise for the simulation of human cognition because they show how structured and abstract representations may emerge from probabilistic unsupervised learning. These networks build a hierarchy of progressively more complex distributed representations of the sensory data by fitting a hierarchical generative model. However, learning in deep networks typically requires big datasets and it can involve millions of connection weights, which implies that simulations on standard computers are unfeasible. Developing realistic, medium-to-large-scale learning models of cognition would therefore seem to require expertise in programming parallel-computing hardware, and this might explain why the use of this promising approach is still largely confined to the machine learning community. Here we show how simulations of deep unsupervised learning can be easily performed on a desktop PC by exploiting the processors of low-cost graphic cards (GPUs without any specific programming effort, thanks to the use of high-level programming routines (available in MATLAB or Python. We also show that even an entry-level graphic card can outperform a small high-performance computing cluster in terms of learning time and with no loss of learning quality. We therefore conclude that graphic card implementations pave the way for a widespread use of deep learning among cognitive scientists for modeling cognition and behavior.

  17. Generation of orientation tools for automated zebrafish screening assays using desktop 3D printing

    Science.gov (United States)

    2014-01-01

    Background The zebrafish has been established as the main vertebrate model system for whole organism screening applications. However, the lack of consistent positioning of zebrafish embryos within wells of microtiter plates remains an obstacle for the comparative analysis of images acquired in automated screening assays. While technical solutions to the orientation problem exist, dissemination is often hindered by the lack of simple and inexpensive ways of distributing and duplicating tools. Results Here, we provide a cost effective method for the production of 96-well plate compatible zebrafish orientation tools using a desktop 3D printer. The printed tools enable the positioning and orientation of zebrafish embryos within cavities formed in agarose. Their applicability is demonstrated by acquiring lateral and dorsal views of zebrafish embryos arrayed within microtiter plates using an automated screening microscope. This enables the consistent visualization of morphological phenotypes and reporter gene expression patterns. Conclusions The designs are refined versions of previously demonstrated devices with added functionality and strongly reduced production costs. All corresponding 3D models are freely available and digital design can be easily shared electronically. In combination with the increasingly widespread usage of 3D printers, this provides access to the developed tools to a wide range of zebrafish users. Finally, the design files can serve as templates for other additive and subtractive fabrication methods. PMID:24886511

  18. From cleanroom to desktop: emerging micro-nanofabrication technology for biomedical applications.

    Science.gov (United States)

    Pan, Tingrui; Wang, Wei

    2011-02-01

    This review is motivated by the growing demand for low-cost, easy-to-use, compact-size yet powerful micro-nanofabrication technology to address emerging challenges of fundamental biology and translational medicine in regular laboratory settings. Recent advancements in the field benefit considerably from rapidly expanding material selections, ranging from inorganics to organics and from nanoparticles to self-assembled molecules. Meanwhile a great number of novel methodologies, employing off-the-shelf consumer electronics, intriguing interfacial phenomena, bottom-up self-assembly principles, etc., have been implemented to transit micro-nanofabrication from a cleanroom environment to a desktop setup. Furthermore, the latest application of micro-nanofabrication to emerging biomedical research will be presented in detail, which includes point-of-care diagnostics, on-chip cell culture as well as bio-manipulation. While significant progresses have been made in the rapidly growing field, both apparent and unrevealed roadblocks will need to be addressed in the future. We conclude this review by offering our perspectives on the current technical challenges and future research opportunities.

  19. The Auroral Planetary Imaging and Spectroscopy (APIS) service

    CERN Document Server

    Lamy, Laurent; Henry, Florence; Sidaner, Pierre Le

    2015-01-01

    The Auroral Planetary Imaging and Spectroscopy (APIS) service, accessible online, provides an open and interactive access to processed auroral observations of the outer planets and their satellites. Such observations are of interest for a wide community at the interface between planetology and magnetospheric and heliospheric physics. APIS consists of (i) a high level database, built from planetary auroral observations acquired by the Hubble Space Telescope (HST) since 1997 with its mostly used Far-UltraViolet spectro-imagers, (ii) a dedicated search interface aimed at browsing efficiently this database through relevant conditional search criteria and (iii) the ability to interactively work with the data online through plotting tools developed by the Virtual Observatory (VO) community, such as Aladin and Specview. This service is VO compliant and can therefore also been queried by external search tools of the VO community. The diversity of available data and the capability to sort them out by relevant physical...

  20. Draft genome sequence of the Algerian bee Apis mellifera intermissa.

    Science.gov (United States)

    Haddad, Nizar Jamal; Loucif-Ayad, Wahida; Adjlane, Noureddine; Saini, Deepti; Manchiganti, Rushiraj; Krishnamurthy, Venkatesh; AlShagoor, Banan; Batainh, Ahmed Mahmud; Mugasimangalam, Raja

    2015-06-01

    Apis mellifera intermissa is the native honeybee subspecies of Algeria. A. m. intermissa occurs in Tunisia, Algeria and Morocco, between the Atlas and the Mediterranean and Atlantic coasts. This bee is very important due to its high ability to adapt to great variations in climatic conditions and due to its preferable cleaning behavior. Here we report the draft genome sequence of this honey bee, its Whole Genome Shotgun project has been deposited at DDBJ/EMBL/GenBank under the accession JSUV00000000. The 240-Mb genome is being annotated and analyzed. Comparison with the genome of other Apis mellifera sub-species promises to yield insights into the evolution of adaptations to high temperature and resistance to Varroa parasite infestation.

  1. Usability of Wearable and Desktop Game-Based Simulations: A Heuristic Evaluation

    Science.gov (United States)

    2010-05-01

    stretch, and people who play videogames will find the control scheme familiar. • Recommendation o Create as many “natural” controls as possible...change. o Needs work in both apps. o People should get better at playing videogames . In all seriousness a longer familiarization session may be

  2. The Desktop Muon Detector: A simple, physics-motivated machine- and electronics-shop project for university students

    CERN Document Server

    Axani, Spencer N; Kirby, Conor

    2016-01-01

    This paper describes an undergraduate-level physics project that incorporates various aspects of machine- and electronics-shop technical development. The desktop muon detector is a self-contained apparatus that employs plastic scintillator as a detection medium and a silicon photomultiplier for light collection. These detectors can be used in conjunction with the provided software to make interesting physics measurements. The total cost of each counter is approximately $100.

  3. Apis florea en Jordanie : origine de la population fondatrice

    OpenAIRE

    HADDAD, Nizar; FUCHS, Stefan; Randall Hepburn, H.; Radloff, Sarah E.

    2009-01-01

    International audience; A recent isolated population of Apis florea has been reported from Aqaba in Jordan at the Red Sea, consisting of numerous colonies within a still limited range which apparently is expanding. This region is about 1500 km apart from its next occurrences in Sudan where it had been introduced and first detected in 1985 and about 2000 km apart from its next natural occurrences in Iran and Oman. These bees apparently have been imported by human transport, most likely by ship...

  4. ADS 2.0: New Architecture, API and Services

    Science.gov (United States)

    Chyla, R.; Accomazzi, A.; Holachek, A.; Grant, C. S.; Elliott, J.; Henneken, E. A.; Thompson, D. M.; Kurtz, M. J.; Murray, S. S.; Sudilovsky, V.

    2015-09-01

    The ADS platform is undergoing the biggest rewrite of its 20-year history. While several components have been added to its architecture over the past couple of years, this talk will concentrate on the underpinnings of ADS's search layer and its API. To illustrate the design of the components in the new system, we will show how the new ADS user interface is built exclusively on top of the API using RESTful web services. Taking one step further, we will discuss how we plan to expose the treasure trove of information hosted by ADS (10 million records and fulltext for much of the Astronomy and Physics refereed literature) to partners interested in using this API. This will provide you (and your intelligent applications) with access to ADS's underlying data to enable the extraction of new knowledge and the ingestion of these results back into the ADS. Using this framework, researchers could run controlled experiments with content extraction, machine learning, natural language processing, etc. In this talk, we will discuss what is already implemented, what will be available soon, and where we are going next.

  5. Carbonic anhydrase from Apis mellifera: purification and inhibition by pesticides.

    Science.gov (United States)

    Soydan, Ercan; Güler, Ahmet; Bıyık, Selim; Şentürk, Murat; Supuran, Claudiu T; Ekinci, Deniz

    2017-12-01

    Carbonic anhydrase (CA) enzymes have been shown to play an important role in ion transport and in pH regulation in several organisms. Despite this information and the wealth of knowledge regarding the significance of CA enzymes, few studies have been reported about bee CA enzymes and the hazardous effects of chemicals. Using Apis mellifera as a model, this study aimed to determine the risk of pesticides on Apis mellifera Carbonic anhydrase enzyme (Am CA). CA was initially purified from Apis mellifera spermatheca for the first time in the literature. The enzyme was purified with an overall purification of ∼35-fold with a molecular weight of ∼32 kDa. The enzyme was then exposed to pesticides, including tebuconazole, propoxur, carbaryl, carbofuran, simazine and atrazine. The six pesticides dose-dependently inhibited in vitro AmCA activity at low micromolar concentrations. IC50 values for the pesticides were 0.0030, 0.0321, 0.0031, 0.0087, 0.0273 and 0.0165 μM, respectively. The AmCA inhibition mechanism of these compounds is unknown at this moment.

  6. Variation morphogeometrics of Africanized honey bees (Apis mellifera in Brazil

    Directory of Open Access Journals (Sweden)

    Lorena A. Nunes

    2012-09-01

    Full Text Available The morphometrics of the honey bee Apis mellifera L., 1758 has been widely studied mainly because this species has great ecological importance, high adaptation capacity, wide distribution and capacity to effectively adapt to different regions. The current study aimed to investigate the morphometric variations of wings and pollen baskets of honey bees Apis mellifera scutellata Lepeletier, 1836 from the five regions in Brazil. We used geometric morphometrics to identify the existence of patterns of variations of shape and size in Africanized honey bees in Brazil 16 years after the classic study with this species, allowing a temporal and spatial comparative analysis using new technological resources to assess morphometrical data. Samples were collected in 14 locations in Brazil, covering the five geographical regions of the country. The shape analysis and multivariate analyses of the wing allowed to observe that there is a geographical pattern among the population of Apis mellifera in Brazil. The geographical variations may be attributed to the large territorial extension of the country in addition to the differences between the bioregions.

  7. Scientific Opinion on the science behind the development of a risk assessment of Plant Protection Products on bees (Apis mellifera, Bombus spp. and solitary bees)

    NARCIS (Netherlands)

    Luttik, R.; Arnold, G.; Boesten, J.J.T.I.; Cresswell, J.; Hart, A.; Pistorius, J.; Sgolastra, F.; Delso, N.S.; Steurbaut, W.; Thompson, H.

    2012-01-01

    The PPR Panel was asked to deliver a scientific opinion on the science behind the development of a risk assessment of plant protection products on bees (Apis mellifera, Bombus spp. and solitary bees). Specific protection goals options were suggested based on the ecosystem services approach. The diff

  8. Improving the API dissolution rate during pharmaceutical hot-melt extrusion I: Effect of the API particle size, and the co-rotating, twin-screw extruder screw configuration on the API dissolution rate.

    Science.gov (United States)

    Li, Meng; Gogos, Costas G; Ioannidis, Nicolas

    2015-01-15

    The dissolution rate of the active pharmaceutical ingredients in pharmaceutical hot-melt extrusion is the most critical elementary step during the extrusion of amorphous solid solutions - total dissolution has to be achieved within the short residence time in the extruder. Dissolution and dissolution rates are affected by process, material and equipment variables. In this work, we examine the effect of one of the material variables and one of the equipment variables, namely, the API particle size and extruder screw configuration on the API dissolution rate, in a co-rotating, twin-screw extruder. By rapidly removing the extruder screws from the barrel after achieving a steady state, we collected samples along the length of the extruder screws that were characterized by polarized optical microscopy (POM) and differential scanning calorimetry (DSC) to determine the amount of undissolved API. Analyses of samples indicate that reduction of particle size of the API and appropriate selection of screw design can markedly improve the dissolution rate of the API during extrusion. In addition, angle of repose measurements and light microscopy images show that the reduction of particle size of the API can improve the flowability of the physical mixture feed and the adhesiveness between its components, respectively, through dry coating of the polymer particles by the API particles.

  9. The end of polling: why and how to transform a REST API into a Data Streaming API?

    CERN Document Server

    CERN. Geneva

    2017-01-01

    We know interactivity is the key to keep our user’s interest alive but we can’t reduce animation to UI anymore. Twitter, Waze, Slack… users are used to have real-time data in applications they love. But how can you turn your static API into a stream of data? By pulling? Pushing? Webhook-ing? When talking about data streaming, we often think about WebSockets. But have you ever heard of Server-Sent Events? In this tools-in-action we will compare those technologies to understand which one you should opt for depending on your usecase, and I’ll show you how we have been reducing the amount of data to transfer even further with JSON-Patch. And because real-time data is not only needed by web (and because it’s much more fun), I’ll show you how we can make a drone dance on streamed APIs.

  10. Federal Procurement Data System - FPDS API

    Data.gov (United States)

    General Services Administration — The Federal Procurement Data System (FPDS) Next Generation has been re-engineered as a real-time federal enterprise information system. Web services based on SOAP...

  11. Federal Procurement Data System - FAADS API

    Data.gov (United States)

    General Services Administration — The Federal Award Assistance Data System (FAADS) has been re-engineered as a real-time federal enterprise information system. Web services based on SOAP and XML,...

  12. NIDA Drug Use Screening Tool API

    Data.gov (United States)

    U.S. Department of Health & Human Services — This Web-based interactive tool provides clinicians with a single-question quick screen about past year alcohol, tobacco, illegal and nonmedical prescription drug...

  13. Modular and scalable RESTful API to sustain STAR collaboration's record keeping

    Science.gov (United States)

    Arkhipkin, D.; Lauret, J.; Shanmuganathan, P. V.

    2015-12-01

    STAR collaboration's record system is a collection of heterogeneous and sparse information associated to each members and institutions. In its original incarnation, only flat information was stored revealing many restrictions such as the lack of historical change information, the inability to keep track of members leaving and re-joining STAR, or the ability to easily extend the saved information as new requirements appeared. In mid-2013, a new project was launched covering an extensive set of revisited requirements. The requirements led us to a design based on a RESTful API, back-end storage engine relying on key/value pair data representation model coupled with a tiered architecture design. This design was motivated by the fact that unifying many STAR tools, relying on the same business logic and storage engine, was a key and central feature for the maintainability and presentation of records. This central service API would leave no ambiguities and provide easy service integration between STAR tools. The new design stores the changes in records dynamically and allows tracking the changes chronologically. The storage engine is extensible as new field of information emerges (member specific or general) without affecting the presentation or the business logic layers. The new record system features a convenient administrative interface, fuzzy algorithms for data entry and search, and provides basic statistics and graphs. Finally, this modular approach is supplemented with access control, allowing private information and administrative operations to be hidden away from public eyes.

  14. Cloning and Sequence Analysis of cDNA Encoding MRJP3 of Apis cerana cerana

    Institute of Scientific and Technical Information of China (English)

    SU Song-kun; ZHNEG Huo-qing; CHEN Sheng-lu; ZHONG Bo-xiong; Stefan Albert

    2005-01-01

    By screening the worker (Apis cerana cerana) heads cDNA library using a fragment of the mrjp3 gene ofApis cerana as probe, 120 positive clones were obtained. The clone containing A. cerana cerana MRJP3 (AccMRJP3) cDNA was selected. Based on the sequencing of the inserts of the positive clone, a sequence of AccMRJP3 cDNA which is 1 887 bp long including a poly (A) tail was obtained. The AccMRJP3 cDNA encompassed an open-reading frame (ORF) with 1 779 bp encoding 593 amino acids. The un-translated regions (UTR) of the 5' end and 3' end are 46 bp and 160 bp in length,respectively. Similar to AmMRJP3 and AdMRJP3, the putative AccMRJP3 also has a repetitive region. The comparison of the repetitive region of AccMRJP3, AmMRJP3 and AdMRJP3 shows some differences between them.

  15. Consequences of new approach of chemical stability tests of active pharmaceutical ingredients (APIs

    Directory of Open Access Journals (Sweden)

    Marzena eJamrógiewicz

    2016-02-01

    Full Text Available There is a great need of broaden look on stability tests of active pharmaceutical ingredients (APIs in comparison with current requirements contained in pharmacopoeia. By usage of many modern analytical methods the conception of monitoring the changes of APIs during initial stage of their exposure to harmful factors has been developed. New knowledge must be acquired in terms of identification of each degradation products, especially volatile ones. Further research as toxicology prediction during in silico studies of determined and identified degradation products is necessary. In silico methods are known as computational toxicology or computer-assisted technologies which are used for predicting toxicology of pharmaceutical substances such as impurities or degradation products. This is a specialized software and databases intended to calculate probability of genotoxicity or mutagenicity of these substances through a chemical structure-based screening process and algorithm specific to a given software program. Applying of new analytical approach is proposed as the usage of PAT tools, XRD, HS-SPME GC-MS/MS, LC-MS/MS for stability testing. Described improvements should be taken into account in case of each drug existing already in the market as well as being implemented as new one.

  16. Atmospheric sulphuric acid and neutral cluster measurements using CI-APi-TOF

    Directory of Open Access Journals (Sweden)

    T. Jokinen

    2011-12-01

    Full Text Available The first ambient measurements using nitrate ion based Chemical Ionization with the Atmospheric Pressure interface Time-Of-Flight mass spectrometer (CI-APi-TOF for sulphuric acid and neutral cluster detection are presented. We have found CI-APi-TOF a highly stable and sensitive tool for molecular sulphuric acid detection. The lowest limit of detection for sulphuric acid was determined to be 3 × 104 molecules cm−3 for two hour averaging. Signals from sulphuric acid clusters up to tetramer accompanied by ammonia were also obtained but these were found to result from naturally charged clusters formed by ion induced clustering in the atmosphere during nucleation. Opposite to earlier studies with cluster mass spectrometers, we had no indication of neutral clusters. The reason is either less efficient charging of clusters in comparison to molecular sulphuric acid, or in low concentration of neutral clusters at our measurement site during these particular nucleation events. We show that utilizing high resolution mass spectrometry is crucial in separating the weak sulfuric acid cluster signal from the other compounds.

  17. Mitochondrial genome of the Levant Region honeybee, Apis mellifera syriaca (Hymenoptera: Apidae).

    Science.gov (United States)

    Haddad, Nizar Jamal

    2016-11-01

    The mitochondrial genome sequence of Levant Region honeybee, Apis mellifera syriaca, is analyzed and presented for the public for the first time. The genome of this honeybee is 15,428 bp in its length, containing 13 protein-coding genes, 22 transfer RNA genes and 2 ribosomal RNA genes. The overall base composition is A (42.88%), C (9.97%), G (5.85%), and T (41.3%), the percentage of A and T being higher than that of G and C. Percentage of non-ATGC characters is 0.007. All the genes are encoded on H-strand, except for four subunit genes (ND1, ND4, ND4L, and ND5), two rRNA genes and eight tRNA genes. The publication of the mitochondrial genome sequence will play a vital role in the conservation genetic projects of A. mellifera, in general, and Apis mellifera syriaca, in particular; moreover, it will be useful for further phylogenetic analysis.

  18. Atmospheric sulphuric acid and neutral cluster measurements using CI-APi-TOF

    Directory of Open Access Journals (Sweden)

    T. Jokinen

    2012-05-01

    Full Text Available The first ambient measurements using nitrate ion based Chemical Ionization with the Atmospheric Pressure interface Time-Of-Flight mass spectrometer (CI-APi-TOF for sulphuric acid and neutral cluster detection are presented. We have found CI-APi-TOF a highly stable and sensitive tool for molecular sulphuric acid detection. The lowest limit of detection for sulphuric acid was determined to be 3.6 × 104 molecules cm−3 for 15 min averaging. Signals from sulphuric acid clusters up to tetramer containing ammonia were also obtained but these were found to result from naturally charged clusters formed by ion induced clustering in the atmosphere during nucleation. Opposite to earlier studies with cluster mass spectrometers, we had no indication of neutral clusters. The reason is either less efficient charging of clusters in comparison to molecular sulphuric acid, or the low concentration of neutral clusters at our measurement site during these particular nucleation events. We show that utilizing high resolution mass spectrometry is crucial in separating the weak sulfuric acid cluster signal from other compounds.

  19. Indiana Humanities Council Request for the Indianapolis Energy Conversion Inst. For Phase I of the Indianapolis Energy Conservation Res Initiative also called the smartDESKTOP Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Keller, John B.

    2007-12-06

    The smartDESKTOP Initiative at the Indiana Humanities Council received critical support in building and delivering a digital desktop for Indiana educators through the Department of Energy Grant DE-FG02-06ER64282. During the project period September 2006 through October of 2007, the number of Indiana educators with accounts on the smartDESKTOP more than tripled from under 2,000 to more than 7,000 accounts. An external review of the project conducted for the purposes of understanding the impact of the service in Indiana schools revealed that the majority of respondents felt that using the smartDESKTOP did reduce the time they spent managing paper. The same study revealed the challenges of implementing a digital desktop meant to help teachers leverage technology to improve their teaching and ultimately student learning. The most significant outcome of this project is that the Indiana Department of Education expressed interest in assuming responsibility for sustaining this project. The transition of the smartDESKTOP to the Indiana Department of Education was effective on November 1, 2007.

  20. Induction bending of API 5L X80 pipes; Curvamento a quente de tubos API 5L X80

    Energy Technology Data Exchange (ETDEWEB)

    Batista, Gilmar Z. [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil)]. E-mail: g.zacca@petrobras.com.br; Naschpitz, Leonardo [Primus Processamento de Tubos S.A. - PROTUBO, Campo Grande, RJ (Brazil)]. E-mail: naschpitz@protubo.com.br

    2005-07-01

    The present work is a part of an extensive program to make possible the application of API 5L X80 in pipeline construction in Brazil. At this stage, the effect of the induction bending process on the microstructure and mechanical properties of the pipe is presented. For this study an API 5L X80 pipe, made by the UOE process, is used. The pipe was manufactured from a plate produced by thermo-mechanically controlled rolling without accelerated cooling. The pipe bending was carried out applying a local induction heating following by water quenching. The bend section, outer and inner curvature regions, of the pipe bend were evaluated and compared with the original pipe. The longitudinal weld and transition zones were not evaluated at this stage. Dimensional analyses, microstructural evaluation, Charpy-V impact tests, and tensile tests were performed. A significant microstructural change was verified in the bend area. The yield strength of the pipe bend was found to be lower than original pipe and standard requirements. Other tensile properties and impact properties are compatible with API 5L X80 requirements. (author)

  1. Is the Sample Good Enough? Comparing Data from Twitter's Streaming API with Twitter's Firehose

    OpenAIRE

    Morstatter, Fred; Pfeffer, Jürgen; Liu, Huan; Carley, Kathleen M.

    2013-01-01

    Twitter is a social media giant famous for the exchange of short, 140-character messages called "tweets". In the scientific community, the microblogging site is known for openness in sharing its data. It provides a glance into its millions of users and billions of tweets through a "Streaming API" which provides a sample of all tweets matching some parameters preset by the API user. The API service has been used by many researchers, companies, and governmental institutions that want to extract...

  2. Use of the API 20E system to identify veterinary Enterobacteriaceae.

    OpenAIRE

    Swanson, E C; Collins, M T

    1980-01-01

    A total of 503 veterinary enteric bacterial pathogens obtained from state veterinary diagnostic laboratories were tested on API 20E strips to determine whether this rapid microidentification system could be utilized for veterinary clinical microbiology. The API 20E strip accurately identified 96% of the veterinary isolates and misidentified 3%. Identifications by the API system and the diagnostic laboratories were in agreement in 85% of the isolates, disagreement on 16% of the isolates, and 1...

  3. ANTHROPOGENIC POLLEN INDICATORS (API FROM ARCHAEOLOGICAL SITES AS LOCAL EVIDENCE OF HUMAN-INDUCED ENVIRONMENTS IN THE ITALIAN PENINSULA

    Directory of Open Access Journals (Sweden)

    A. M. Mercuri

    2013-04-01

    Full Text Available Pollen data from twenty-six archaeological sites are reviewed to investigate the development of human-induced environments through the presence of selected Anthropogenic Pollen Indicators (API. The sites are located in six Italian regions - Veneto, Emilia Romagna, Tuscany, Basilicata, Calabria, and Sicily - and in the Republic of San Marino. Their chronology spans from the Bronze to the Renaissance ages, from approximately 4200 to 500 years BP. The API which are common in these sites are properly considered important markers of human activity and anthropization in the Mediterranean area. The most frequent API taxa in pollen spectra are seven: Artemisia, Centaurea, Cichorieae and Plantago are ubiquitous and therefore they have the major relevance, followed by cereals and Urtica, and by Trifolium type. The spread of plants producing these pollen grains is sometimes marked by high percentage values in pollen spectra. Pollen records show that, as expected, cereals and wild synanthropic herbs were widespread near archaeological sites but local differences are evident. Ecological and chrono-cultural reasons may be at the base of the observed differences. In general, the synanthropic plants well represent the xeric environments that developed as a result of the continuous human pressure and changes in soil compositions. These changes have occurred especially during the mid and late Holocene.

  4. IMIS desktop & smartphone software solutions for monitoring spacecrafts' payload from anywhere

    Science.gov (United States)

    Baroukh, J.; Queyrut, O.; Airaud, J.

    In the past years, the demand for satellite remote operations has increased guided by on one hand, the will to reduce operations cost (on-call operators out of business hours), and on the other hand, the development of cooperation space missions resulting in a world wide distribution of engineers and science team members. Only a few off-the-shelf solutions exist to fulfill the need of remote payload monitoring, and they mainly use proprietary devices. The recent advent of mobile technologies (laptops, smartphones and tablets) as well as the worldwide deployment of broadband networks (3G, Wi-Fi hotspots), has opened up a technical window that brings new options. As part of the Mars Science Laboratory (MSL) mission, the Centre National D'Etudes Spatiales (CNES, the French space agency) has developed a new software solution for monitoring spacecraft payloads. The Instrument Monitoring Interactive Software (IMIS) offers state-of-the-art operational features for payload monitoring, and can be accessed remotely. It was conceived as a generic tool that can be used for heterogeneous payloads and missions. IMIS was designed as a classical client/server architecture. The server is hosted at CNES and acts as a data provider while two different kinds of clients are available depending on the level of mobility required. The first one is a rich client application, built on Eclipse framework, which can be installed on usual operating systems and communicates with the server through the Internet. The second one is a smartphone application for any Android platform, connected to the server thanks to the mobile broadband network or a Wi-Fi connection. This second client is mainly devoted to on-call operations and thus only contains a subset of the IMIS functionalities. This paper describes the operational context, including security aspects, that led IMIS development, presents the selected software architecture and details the various features of both clients: the desktop and the sm

  5. Developing JAVA Card Application with RMI API

    Science.gov (United States)

    JunWu, Xu; JunLing, Liang

    This paper describes research in the use of the RMI to develop Java Card applications. the Java Card RMI (JCRMI), which is based on the J2SE RMI distributed-object model. In the RMI model a server application creates and makes accessible remote objects, and a client application obtains remote references to the server's remote objects, and then invokes remote methods on them. In JCRMI, the Java Card applet is the server, and the host application is the client.

  6. Facebook Application Development with Graph API Cookbook

    CERN Document Server

    Srivastava, Shashwat

    2011-01-01

    Written in a cookbook style, this book offers solutions using a recipe-based approach. Each recipe contains step-by-step instructions followed by an analysis of what was done in each task and other useful information. The cookbook approach means you can dive into whatever recipes you want in no particular order. The book provides tips and tricks to the most common problems and scenarios faced in Facebook Application Development. This book is written for Facebook developers ranging from novice to expert. It uses PHP, HTML and jQuery, the most commonly used platforms, to build applications in Fa

  7. Accelerated Numerical Processing API Based on GPU Technology Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The recent performance increases in graphics processing units (GPUs) have made graphics cards an attractive platform for implementing computationally intense...

  8. Solar Eclipse Computer API: Planning Ahead for August 2017

    Science.gov (United States)

    Bartlett, Jennifer L.; Chizek Frouard, Malynda; Lesniak, Michael V.; Bell, Steve

    2016-01-01

    With the total solar eclipse of 2017 August 21 over the continental United States approaching, the U.S. Naval Observatory (USNO) on-line Solar Eclipse Computer can now be accessed via an application programming interface (API). This flexible interface returns local circumstances for any solar eclipse in JavaScript Object Notation (JSON) that can be incorporated into third-party Web sites or applications. For a given year, it can also return a list of solar eclipses that can be used to build a more specific request for local circumstances. Over the course of a particular eclipse as viewed from a specific site, several events may be visible: the beginning and ending of the eclipse (first and fourth contacts), the beginning and ending of totality (second and third contacts), the moment of maximum eclipse, sunrise, or sunset. For each of these events, the USNO Solar Eclipse Computer reports the time, Sun's altitude and azimuth, and the event's position and vertex angles. The computer also reports the duration of the total phase, the duration of the eclipse, the magnitude of the eclipse, and the percent of the Sun obscured for a particular eclipse site. On-line documentation for using the API-enabled Solar Eclipse Computer, including sample calls, is available (http://aa.usno.navy.mil/data/docs/api.php). The same Web page also describes how to reach the Complete Sun and Moon Data for One Day, Phases of the Moon, Day and Night Across the Earth, and Apparent Disk of a Solar System Object services using API calls.For those who prefer using a traditional data input form, local circumstances can still be requested that way at http://aa.usno.navy.mil/data/docs/SolarEclipses.php. In addition, the 2017 August 21 Solar Eclipse Resource page (http://aa.usno.navy.mil/data/docs/Eclipse2017.php) consolidates all of the USNO resources for this event, including a Google Map view of the eclipse track designed by Her Majesty's Nautical Almanac Office (HMNAO). Looking further ahead, a

  9. A New Strategy on Open APIs for Telecom Operators%电信运营商能力开放新思路探讨

    Institute of Scientific and Technical Information of China (English)

    王夐婧; 贺佳莹; 吕昌春

    2013-01-01

      从技术和市场角度简要介绍了电信运营商在能力开放方面的优势;详细阐述了:电信运营商能力开放项目现状及创新应用、能力开放平台现状及策略转型,能力开放项目、对象、向开放对象提供的服务方式,基于IMS网络的能力开放架构及开放用户数据。%  It presents the advantages of telecom operators on open API from the aspects of technology and market, expounds the current state of open API for telecom operators and innovate application, the platform situation and strategy transform, open API proj-ect, object, serving mode for open object, open API architecture based on IMS and open subscriber data.

  10. A Personal Desktop Liquid-Metal Printer as a Pervasive Electronics Manufacturing Tool for Society in the Near Future

    Directory of Open Access Journals (Sweden)

    Yang Jun

    2015-12-01

    Full Text Available It has long been a dream in the electronics industry to be able to write out electronics directly, as simply as printing a picture onto paper with an office printer. The first-ever prototype of a liquid-metal printer has been invented and demonstrated by our lab, bringing this goal a key step closer. As part of a continuous endeavor, this work is dedicated to significantly extending such technology to the consumer level by making a very practical desktop liquid-metal printer for society in the near future. Through the industrial design and technical optimization of a series of key technical issues such as working reliability, printing resolution, automatic control, human-machine interface design, software, hardware, and integration between software and hardware, a high-quality personal desktop liquid-metal printer that is ready for mass production in industry was fabricated. Its basic features and important technical mechanisms are explained in this paper, along with demonstrations of several possible consumer end-uses for making functional devices such as light-emitting diode (LED displays. This liquid-metal printer is an automatic, easy-to-use, and low-cost personal electronics manufacturing tool with many possible applications. This paper discusses important roles that the new machine may play for a group of emerging needs. The prospective future of this cutting-edge technology is outlined, along with a comparative interpretation of several historical printing methods. This desktop liquid-metal printer is expected to become a basic electronics manufacturing tool for a wide variety of emerging practices in the academic realm, in industry, and in education as well as for individual end-users in the near future.

  11. jmzML, an open-source Java API for mzML, the PSI standard for MS data.

    Science.gov (United States)

    Côté, Richard G; Reisinger, Florian; Martens, Lennart

    2010-04-01

    We here present jmzML, a Java API for the Proteomics Standards Initiative mzML data standard. Based on the Java Architecture for XML Binding and XPath-based XML indexer random-access XML parser, jmzML can handle arbitrarily large files in minimal memory, allowing easy and efficient processing of mzML files using the Java programming language. jmzML also automatically resolves internal XML references on-the-fly. The library (which includes a viewer) can be downloaded from http://jmzml.googlecode.com.

  12. Improvements and extensions to API 618 related to pulsation and mechanical response studies

    NARCIS (Netherlands)

    Eijk, A.; Smeulers, J.P.M.; Blodgett, L.E.; Smalley, A.J.

    1999-01-01

    Purchasers of reciprocating compressors need a standard to help ensure reliable installations. The PNEUROP standard evolved in Europe, and the API 618 Standard in the U.S.A. Frequent application and generally good experience, worldwide, have led to four releases of API 618, the last dated June 1995.

  13. Complete mitochondrial genome of the Algerian honeybee, Apis mellifera intermissa (Hymenoptera: Apidae).

    Science.gov (United States)

    Hu, Peng; Lu, Zhi-Xiang; Haddad, Nizar; Noureddine, Adjlane; Loucif-Ayad, Wahida; Wang, Yong-Zhi; Zhao, Ren-Bin; Zhang, Ai-Ling; Guan, Xin; Zhang, Hai-Xi; Niu, Hua

    2016-05-01

    In this study, the complete mitochondrial genome sequence of Algerian honeybee, Apis mellifera intermissa, is analyzed for the first time. The results show that this genome is 16,336 bp in length, and contains 13 protein-coding genes, 22 transfer RNA genes, 2 ribosomal RNA genes, and 1 control region (D-loop). The overall base composition is A (43.2%), C (9.8%), G (5.6%), and T (41.4%), so the percentage of A and T (84.6%) is considerably higher than that of G and C. All the genes are encoded on H-strand, except for four subunit genes (ND1, ND4, ND4L, and ND5), two rRNA genes (12S and 16S rRNA), and eight tRNA genes. The complete mitochondrial genome sequence reported here would be useful for further phylogenetic analysis and conservation genetic studies in A. m. intermissa.

  14. APIS - a novel approach for conditioning honey bees

    Directory of Open Access Journals (Sweden)

    Nicholas Hagen Kirkerud

    2013-04-01

    Full Text Available Honey bees perform robustly in different conditioning paradigms. This makes them excellent candidates for studying mechanisms of learning and memory at both an individual and a population level. Here we introduce a novel method of honey bee conditioning: APIS, the Automatic Performance Index System. In an enclosed walking arena where the interior is covered with an electric grid, presentation of odours from either end can be combined with weak electric shocks to form aversive associations. To quantify behavioural responses, we continuously monitor the movement of the bee by an automatic tracking system. We found that escapes from one side to the other, changes in velocity as well as distance and time spent away from the punished odour are suitable parameters to describe the bee’s learning capabilities.Our data show that in a short-term memory test the response rate for the conditioned stimulus in APIS correlates well with response rate obtained from conventional Proboscis Extension Response (PER-conditioning. Additionally, we discovered that bees modulate their behaviour to aversively learned odours by reducing their rate, speed and magnitude of escapes and that both generalisation and extinction seem to be different between appetitive and aversive stimuli. The advantages of this automatic system make it ideal for assessing learning rates in a standardised and convenient way, and its flexibility adds to our toolbox for studying honey bee behaviour.

  15. Parasitic Cape honeybee workers, Apis mellifera capensis, evade policing

    Science.gov (United States)

    Martin, Stephen J.; Beekman, Madeleine; Wossler, Theresa C.; Ratnieks, Francis L. W.

    2002-01-01

    Relocation of the Cape honeybee, Apis mellifera capensis, by bee-keepers from southern to northern South Africa in 1990 has caused widespread death of managed African honeybee, A. m. scutellata, colonies. Apis mellifera capensis worker bees are able to lay diploid, female eggs without mating by means of automictic thelytoky (meiosis followed by fusion of two meiotic products to restore egg diploidy), whereas workers of other honeybee subspecies are able to lay only haploid, male eggs. The A. m. capensis workers, which are parasitizing and killing A. m. scutellata colonies in northern South Africa, are the asexual offspring of a single, original worker in which the small amount of genetic variation observed is due to crossing over during meiosis (P. Kryger, personal communication). Here we elucidate two principal mechanisms underlying this parasitism. Parasitic A. m. capensis workers activate their ovaries in host colonies that have a queen present (queenright colonies), and they lay eggs that evade being killed by other workers (worker policing)-the normal fate of worker-laid eggs in colonies with a queen. This unique parasitism by workers is an instance in which a society is unable to control the selfish actions of its members.

  16. Polymorphism analysis of csd gene in six Apis mellifera subspecies.

    Science.gov (United States)

    Wang, Zilong; Liu, Zhiyong; Wu, Xiaobo; Yan, Weiyu; Zeng, Zhijiang

    2012-03-01

    The complementary sex determination (csd) gene is the primary gene determining the gender of honey bees (Apis spp). In this study we analyzed the polymorphism of csd gene in six Apis mellifera subspecies. The genomic region 3 of csd gene in these six A. mellifera was cloned, and identified. A total of 79 haplotypes were obtained from these six subspecies. Analysis showed that region 3 of csd gene has a high level of polymorphism in all the six A. mellifera subspecies. The A. m. anatolica subspecies has a slightly higher nucleotide diversity (π) than other subspecies, while the π values showed no significant difference among the other five subspecies. The phylogenetic tree showed that all the csd haplotypes from different A. mellifera subspecies are scattered throughout the tree, without forming six different clades. Population differentiation analysis showed that there are significant genetic differentiations among some of the subspecies. The NJ phylogenetic tree showed that the A. m. caucasica and A. m. carnica have the closest relationship, followed by A. m. ssp, A. m. ligustica, A. m. carpatica and A. m. anatolica that were gathered in the tree in turn.

  17. 往复压缩机标准API-618、API-11P的异同点及其应用浅谈%The Similarities and Differences of Reciprocating Compressor Standards of API-618 and API-11P and Discussion of Its Application

    Institute of Scientific and Technical Information of China (English)

    李明悦; 扈滨

    2011-01-01

    PI Standard 618 and API Specification 11P are the standards for reciprocating compressors by American Petroleum Institute ( API) .This paper has speeified the applications of the two standards in the compressors which used in the Cas Treatment Plant of SES natural gas pmject.And the similarities and differences between them are compared.%API Standard 618和API Specification 11P都是美国石油学会(API)针对往复压缩机制定的标准.结合中海石油SES天然气项目中的气体处理厂压缩机单元对这两个标准的应用,对两者之间的异同点进行比较.

  18. Identification, recombinant expression, and characterization of the 100 kDa high molecular weight Hymenoptera venom allergens Api m 5 and Ves v 3.

    Science.gov (United States)

    Blank, Simon; Seismann, Henning; Bockisch, Benjamin; Braren, Ingke; Cifuentes, Liliana; McIntyre, Mareike; Rühl, Dana; Ring, Johannes; Bredehorst, Reinhard; Ollert, Markus W; Grunwald, Thomas; Spillner, Edzard

    2010-05-01

    Insect stings can cause life-threatening IgE-mediated anaphylactic reactions in venom-allergic patients. Although several compounds have already been described as venom allergens, prominent allergen candidates especially in the higher m.w. range have still remained elusive. Tandem mass spectrometry-based sequencing assigned a candidate gene to the most prominent putative high m.w. allergen Api m 5 (allergen C) in honeybee (Apis mellifera) venom and also allowed identification of its homologue Ves v 3 in yellow jacket (Vespula vulgaris) venom. Both proteins exhibit a pronounced sequence identity to human dipeptidyl peptidase IV or CD26. Reactivity of a human IgE mAb verified the presence of these proteins in the venoms. Both proteins were produced in insect cells and characterized for their enzymatic activity as well as their allergenic potential using sera and basophils from insect venom-allergic patients. Both Api m 5 and Ves v 3 were recognized by specific IgE of the majority of patients even in the absence of cross-reactive carbohydrate determinants. Serologic IgE reactivity closely matched activation of human basophils by Api m 5 or Ves v 3, thus underlining their relevance in functional assays. With Api m 5 and Ves v 3, a new pair of homologous allergens becomes available for future clinical applications in diagnosis and therapy that may also contribute to the understanding of molecular mechanisms of insect venoms. Moreover, the patient IgE reactivity together with the cellular activation demonstrates for the first time the relevance of high m.w. allergens in the context of hymenoptera venom allergy.

  19. PGVL Hub: An integrated desktop tool for medicinal chemists to streamline design and synthesis of chemical libraries and singleton compounds.

    Science.gov (United States)

    Peng, Zhengwei; Yang, Bo; Mattaparti, Sarathy; Shulok, Thom; Thacher, Thomas; Kong, James; Kostrowicki, Jaroslav; Hu, Qiyue; Na, James; Zhou, Joe Zhongxiang; Klatte, David; Chao, Bo; Ito, Shogo; Clark, John; Sciammetta, Nunzio; Coner, Bob; Waller, Chris; Kuki, Atsuo

    2011-01-01

    PGVL Hub is an integrated molecular design desktop tool that has been developed and globally deployed throughout Pfizer discovery research units to streamline the design and synthesis of combinatorial libraries and singleton compounds. This tool supports various workflows for design of singletons, combinatorial libraries, and Markush exemplification. It also leverages the proprietary PGVL virtual space (which contains 10(14) molecules spanned by experimentally derived synthesis protocols and suitable reactants) for lead idea generation, lead hopping, and library design. There had been an intense focus on ease of use, good performance and robustness, and synergy with existing desktop tools such as ISIS/Draw and SpotFire. In this chapter we describe the three-tier enterprise software architecture, key data structures that enable a wide variety of design scenarios and workflows, major technical challenges encountered and solved, and lessons learned during its development and deployment throughout its production cycles. In addition, PGVL Hub represents an extendable and enabling platform to support future innovations in library and singleton compound design while being a proven channel to deliver those innovations to medicinal chemists on a global scale.

  20. Environmental Effects of Hydrokinetic Turbines on Fish: Desktop and Laboratory Flume Studies

    Energy Technology Data Exchange (ETDEWEB)

    Jacobson, Paul T. [Electric Power Research Institute; Amaral, Stephen V. [Alden Research Laboratory; Castro-Santos, Theodore [U.S. Geological Survey; Giza, Dan [Alden Research Laboratory; Haro, Alexander J. [U.S. Geological Survey; Hecker, George [Alden Research Laboratory; McMahon, Brian [Alden Research Laboratory; Perkins, Norman [Alden Research Laboratory; Pioppi, Nick [Alden Research Laboratory

    2012-12-31

    This collection of three reports describes desktop and laboratory flume studies that provide information to support assessment of the potential for injury and mortality of fish that encounter hydrokinetic turbines of various designs installed in tidal and river environments. Behavioral responses to turbine exposure also are investigated to support assessment of the potential for disruptions to upstream and downstream movements of fish. The studies: (1) conducted an assessment of potential injury mechanisms using available data from studies with conventional hydro turbines; (2) developed theoretical models for predicting blade strike probabilities and mortality rates; and (3) performed flume testing with three turbine designs and several fish species and size groups in two laboratory flumes to estimate survival rates and document fish behavior. The project yielded three reports which this document comprises. The three constituent documents are addressed individually below Fish Passage Through Turbines: Application of Conventional Hydropower Data to Hydrokinetic Technologies Fish passing through the blade sweep of a hydrokinetic turbine experience a much less harsh physical environment than do fish entrained through conventional hydro turbines. The design and operation of conventional turbines results in high flow velocities, abrupt changes in flow direction, relatively high runner rotational and blade speeds, rapid and significant changes in pressure, and the need for various structures throughout the turbine passageway that can be impacted by fish. These conditions generally do not occur or are not significant factors for hydrokinetic turbines. Furthermore, compared to conventional hydro turbines, hydrokinetic turbines typically produce relatively minor changes in shear, turbulence, and pressure levels from ambient conditions in the surrounding environment. Injuries and mortality from mechanical injuries will be less as well, mainly due to low rotational speeds and

  1. Effect of Heat Treatment on the Mechanical Properties and Microstructure of a API 5CT J55 Pipeline Steel

    Directory of Open Access Journals (Sweden)

    Soria-Aguilar Ma. de Jesús

    2015-09-01

    Full Text Available The effects of two different post-weld heat treatment cycles on the microstructure and mechanical properties of welded API 5CT J55 steels were investigated in the present work. Experiments were carried out based on a Taguchi experimental design. Ortogonal arrays (L9 of Taguchi and statistical analysis of variance (ANOVA were employed to determine the impact of the heat treatment parameters on the microstructure and mechanical properties of experimental steel. From the results of ANOVA, there were obtained the empirical equations for optimizing the heat treating conditions that lead to the best mechanical properties.

  2. Asynchronous API Pattern and its Application%异步接口模式及其应用

    Institute of Scientific and Technical Information of China (English)

    何华海; 丁柯

    2002-01-01

    In distributed systems,high efficiency can be achieved using asynchronous API between client and server.This paper provides an architectural pattern that implements asynchronous API generally. Asynchronous methods donot execute operations directly,however,they delegate the sending and receiving process to individual threads via aqueue ,the client deals with results by means of callback ,wait or check. Synchronous API is implemented on the baseof asynchronous API. Presently the asynchronous API pattern has been employed in the implementation of messagequeue middleware ISMQ.

  3. API5 confers cancer stem cell-like properties through the FGF2-NANOG axis

    Science.gov (United States)

    Song, K-H; Cho, H; Kim, S; Lee, H-J; Oh, S J; Woo, S R; Hong, S-O; Jang, H S; Noh, K H; Choi, C H; Chung, J-Y; Hewitt, S M; Kim, J-H; Son, M; Kim, S-H; Lee, B I; Park, H-C; Bae, Y-K; Kim, T W

    2017-01-01

    Immune selection drives the evolution of tumor cells toward an immune-resistant and cancer stem cell (CSC)-like phenotype. We reported that apoptosis inhibitor-5 (API5) acts as an immune escape factor, which has a significant role in controlling immune resistance to antigen-specific T cells, but its functional association with CSC-like properties remains largely unknown. In this study, we demonstrated for the first time that API5 confers CSC-like properties, including NANOG expression, the frequency of CD44-positive cells and sphere-forming capacity. Critically, these CSC-like properties mediated by API5 are dependent on FGFR1 signaling, which is triggered by E2F1-dependent FGF2 expression. Furthermore, we uncovered the FGF2-NANOG molecular axis as a downstream component of API5 signaling that is conserved in cervical cancer patients. Finally, we found that the blockade of FGFR signaling is an effective strategy to control API5high human cancer. Thus, our findings reveal a crucial role of API5 in linking immune resistance and CSC-like properties, and provide the rationale for its therapeutic application for the treatment of API5+ refractory tumors. PMID:28092370

  4. api, A novel Medicago truncatula symbiotic mutant impaired in nodule primordium invasion.

    Science.gov (United States)

    Teillet, Alice; Garcia, Joseph; de Billy, Françoise; Gherardi, Michèle; Huguet, Thierry; Barker, David G; de Carvalho-Niebel, Fernanda; Journet, Etienne-Pascal

    2008-05-01

    Genetic approaches have proved to be extremely useful in dissecting the complex nitrogen-fixing Rhizobium-legume endosymbiotic association. Here we describe a novel Medicago truncatula mutant called api, whose primary phenotype is the blockage of rhizobial infection just prior to nodule primordium invasion, leading to the formation of large infection pockets within the cortex of noninvaded root outgrowths. The mutant api originally was identified as a double symbiotic mutant associated with a new allele (nip-3) of the NIP/LATD gene, following the screening of an ethylmethane sulphonate-mutagenized population. Detailed characterization of the segregating single api mutant showed that rhizobial infection is also defective at the earlier stage of infection thread (IT) initiation in root hairs, as well as later during IT growth in the small percentage of nodules which overcome the primordium invasion block. Neither modulating ethylene biosynthesis (with L-alpha-(2-aminoethoxyvinylglycine or 1-aminocyclopropane-1-carboxylic acid) nor reducing ethylene sensitivity in a skl genetic background alters the basic api phenotype, suggesting that API function is not closely linked to ethylene metabolism or signaling. Genetic mapping places the API gene on the upper arm of the M. truncatula linkage group 4, and epistasis analyses show that API functions downstream of BIT1/ERN1 and LIN and upstream of NIP/LATD and the DNF genes.

  5. EDGE REMOVAL OF 3D POLYGONAL MODEL USING MAYA API

    Directory of Open Access Journals (Sweden)

    SAMEER ARORA

    2010-09-01

    Full Text Available In various applications of computer graphics, 3D polygonal modeling is used, which consists millions of triangular polygon. In this polygon attributes – vertices, edges and faces’ details are to be stored. In order to control the processing time, storing space, and transfer speed, it is often required to reduce the information ofthese polygonal 3D models. In this paper an effort is made to reduce the number of edges. There are various methods to reduce faces and edges of these 3D models. A C++ dynamic link library as Maya Plugin has been created to remove number of edges of 3D triangular polygon model using the Quadric Error Metrics (QEM in MAYA v2010 x64 API. QEM allows fast and accurate geometric simplification of 3D models.

  6. AES Encryption and Decryption Using Direct3D 10 API

    Directory of Open Access Journals (Sweden)

    Adrian Marius Chiuta

    2011-06-01

    Full Text Available Current video cards (GPUs – Graphics Processing Units are very programmable, have become much more powerful than the CPUs and they are very affordable. In this paper, we present an implementation for the AES algorithm using Direct3D 10 certified GPUs. The graphics API Direct3D 10 is the first version that allows the use of integer operations, making from the traditional GPUs (that works only with floating point numbers, General Purpose GPUs that can be used for a large number of algorithms, including encryption. We present the performance of the symmetric key encryption algorithm – AES, on a middle range GPU and on a middle range quad core CPU. On the testing system, the developed solution is almost 3 times faster on the GPU than on one single core CPU, showing that the GPU can perform as an efficient cryptographic accelerator.

  7. Fragilización por Hidrógeno de los Aceros API 5L X60 y API 5L X80 Hydrogen Embrittlement of API 5L X60 and API 5L X80 Steels

    OpenAIRE

    Bruno A Araújo; Jorge A Palma; Vilar, Eudésio O.; Silva, Antonio A.

    2011-01-01

    Se ha determinado el comportamiento mecánico de los aceros API 5L grados X60 y X80, fragilizados por hidrógeno ambiental y por hidrógeno interno. El potencial y la densidad de corriente para la generación del hidrógeno fueron determinados por polarización potenciodinámica, y el tiempo de saturación estimado a partir de datos de difusividad y solubilidad obtenidos en ensayos de permeación con una célula electroquímica. La carga de hidrógeno para reproducir las condiciones de la fragilización p...

  8. Pheromonal contest between honeybee workers ( Apis mellifera capensis)

    Science.gov (United States)

    Moritz, R. F. A.; Simon, U. E.; Crewe, R. M.

    2000-10-01

    Queenless workers of the Cape honeybee ( Apis mellifera capensis) can develop into reproductives termed pseudoqueens. Although they morphologically remain workers they become physiologically queenlike, produce offspring, and secrete mandibular gland pheromones similar to those of true queens. However, after queen loss only very few workers gain pseudoqueen status. A strong intracolonial selection governs which workers start oviposition and which remain sterile. The "queen substance", 9-keto-2(E)-decenoic acid (9-ODA), the dominant compound of the queen's mandibular gland pheromones, suppresses the secretion of queenlike mandibular gland pheromones in workers. It may act as an important signal in pseudoqueen selection. By analysing the mandibular gland pheromones of workers kept in pairs, we found that A. m. capensis workers compete to produce the strongest queen-like signal.

  9. A non-policing honey bee colony (Apis mellifera capensis)

    Science.gov (United States)

    Beekman, Madeleine; Good, Gregory; Allsopp, Mike; Radloff, Sarah; Pirk, Chris; Ratnieks, Francis

    2002-09-01

    In the Cape honey bee Apis mellifera capensis, workers lay female eggs without mating by thelytokous parthenogenesis. As a result, workers are as related to worker-laid eggs as they are to queen-laid eggs and therefore worker policing is expected to be lower, or even absent. This was tested by transferring worker- and queen-laid eggs into three queenright A. m. capensis discriminator colonies and monitoring their removal. Our results show that worker policing is variable in A. m. capensis and that in one colony worker-laid eggs were not removed. This is the first report of a non-policing queenright honey bee colony. DNA microsatellite and morphometric analysis suggests that the racial composition of the three discriminator colonies was different. The variation in policing rates could be explained by differences in degrees of hybridisation between A. m. capensis and A. m. scutellata, although a larger survey is needed to confirm this.

  10. Clarification of some api characteristics in relation to caribou (Rangifer tarandus

    Directory of Open Access Journals (Sweden)

    William O. Pruitt, Jr.

    1990-09-01

    Full Text Available A total of 2177 comparisons of api hardness vs. density in northern Saskatchewan, southeastern Manitoba and northeastern Finland revealed no consistent correlation (r varied from +.70 to -.17. A total of 1395 comparisons of horizontal hardness of the top layer of api to vertical hardness of the same layer of api in southeastern Manitoba, northeastern Finland and far eastern middle Finland revealed no consistent correlation (r varied from +.99 to -.20. Therefore one cannot substitute density for hardness nor horizontal hardness of the top layer for vertical hardness of the top layer in the terms of the Värriö Snow Index.

  11. Determination of acoustoelastic constant in API-5L-X70 welded pipes; Determinacao da constante acustoelastica de tubos API-5L-X70 com solda

    Energy Technology Data Exchange (ETDEWEB)

    Bittencourt, Marcelo de Siqueira Queiroz; Fonseca, Manoel Antonio da Costa [Instituto de Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil); Oliveira, Carlos Henrique Francisco de [PETROBRAS S.A., Rio de de Janeiro, RJ (Brazil)

    2008-07-01

    To preserve the environment and avoid financial losses resulting from leaks in the transport of natural oil and gas the industry is particularly concerned to ensure the structural integrity of their pipelines. Grounded pipes may be exposed to damages due to unstable soil movement, and in extreme cases, to failure. Then, techniques to assess stress in pipelines are of central importance. The ultrasonic birefringence technique is an efficient method to measure residual stress. It is based on the changing velocity of the shear wave when it crosses a material under stress; this phenomenon is known as acoustoelasticity. The knowledge of the parameter called acoustoelastic constant is necessary to measure stress using this technique. By the mechanical conformation in the manufacture of welded tubes, from rolled plates, different anisotropy degrees are showed around the cross section of these tubes. In this paper it was studied the acoustoelastic constant for the API-5L-X70 steel pipes, with different thicknesses, diameters and manufacturing processes so as to be able to use this technique to stress measurement in pipelines. (author)

  12. The Arabidopsis apyrase AtAPY1 is localized in the Golgi instead of the extracellular space

    Directory of Open Access Journals (Sweden)

    Schiller Madlen

    2012-07-01

    Full Text Available Abstract Background The two highly similar Arabidopsis apyrases AtAPY1 and AtAPY2 were previously shown to be involved in plant growth and development, evidently by regulating extracellular ATP signals. The subcellular localization of AtAPY1 was investigated to corroborate an extracellular function. Results Transgenic Arabidopsis lines expressing AtAPY1 fused to the SNAP-(O6-alkylguanine-DNA alkyltransferase-tag were used for indirect immunofluorescence and AtAPY1 was detected in punctate structures within the cell. The same signal pattern was found in seedlings stably overexpressing AtAPY1-GFP by indirect immunofluorescence and live imaging. In order to identify the nature of the AtAPY1-positive structures, AtAPY1-GFP expressing seedlings were treated with the endocytic marker stain FM4-64 (N-(3-triethylammoniumpropyl-4-(p-diethylaminophenyl-hexatrienyl-pyridinium dibromide and crossed with a transgenic line expressing the trans-Golgi marker Rab E1d. Neither FM4-64 nor Rab E1d co-localized with AtAPY1. However, live imaging of transgenic Arabidopsis lines expressing AtAPY1-GFP and either the fluorescent protein-tagged Golgi marker Membrin 12, Syntaxin of plants 32 or Golgi transport 1 protein homolog showed co-localization. The Golgi localization was confirmed by immunogold labeling of AtAPY1-GFP. There was no indication of extracellular AtAPY1 by indirect immunofluorescence using antibodies against SNAP and GFP, live imaging of AtAPY1-GFP and immunogold labeling of AtAPY1-GFP. Activity assays with AtAPY1-GFP revealed GDP, UDP and IDP as substrates, but neither ATP nor ADP. To determine if AtAPY1 is a soluble or membrane protein, microsomal membranes were isolated and treated with various solubilizing agents. Only SDS and urea (not alkaline or high salt conditions were able to release the AtAPY1 protein from microsomal membranes. Conclusions AtAPY1 is an integral Golgi protein with the substrate specificity typical for Golgi apyrases. It is

  13. IgE recognition of chimeric isoforms of the honeybee (Apis mellifera) venom allergen Api m 10 evaluated by protein array technology.

    Science.gov (United States)

    Van Vaerenbergh, Matthias; De Smet, Lina; Rafei-Shamsabadi, David; Blank, Simon; Spillner, Edzard; Ebo, Didier G; Devreese, Bart; Jakob, Thilo; de Graaf, Dirk C

    2015-02-01

    Api m 10 has recently been established as novel major allergen that is recognized by more than 60% of honeybee venom (HBV) allergic patients. Previous studies suggest Api m 10 protein heterogeneity which may have implications for diagnosis and immunotherapy of HBV allergy. In the present study, RT-PCR revealed the expression of at least nine additional Api m 10 transcript isoforms by the venom glands. Two distinct mechanisms are responsible for the generation of these isoforms: while the previously known variant 2 is produced by an alternative splicing event, novel identified isoforms are intragenic chimeric transcripts. To the best of our knowledge, this is the first report of the identification of chimeric transcripts generated by the honeybee. By a retrospective proteomic analysis we found evidence for the presence of several of these isoforms in the venom proteome. Additionally, we analyzed IgE reactivity to different isoforms by protein array technology using sera from HBV allergic patients, which revealed that IgE recognition of Api m 10 is both isoform- and patient-specific. While it was previously demonstrated that the majority of HBV allergic patients display IgE reactivity to variant 2, our study also shows that some patients lacking IgE antibodies for variant 2 display IgE reactivity to two of the novel identified Api m 10 variants, i.e. variants 3 and 4.

  14. Histochemical Comparison of the Hypopharyngeal Gland in Apis cerana Fabricius, 1793 Workers and Apis mellifera Linnaeus, 1758 Workers

    Directory of Open Access Journals (Sweden)

    Guntima Suwannapong

    2010-01-01

    Full Text Available Hypopharyngeal glands of honeybee are age-dependent structures that change with the size of acini and are correlated with various social behaviors. The histochemical structure of Apis cerana and A. mellifera worker hypopharyngeal glands in four different developmental stages wes stained with ninhydrin Schiff's and periodic acid Schiff's reagents (PAS for localization of proteins and carbohydrates, respectively, and examined with light microscopy. Nurse bees of both honeybee species had significantly larger glands as compared to guards and forgers, but there were no statistically significant differences between these two species after accounting for caste. Gland protein concentration increased progressively in nurse bees, and this was correlated with the appearance of enriched protein granules in the cytoplasm. In addition, the hypopharyngeal gland protein concentration of A. mellifera was higher than that of A. cerana even though gland size was not significantly different between species. However, gland size was shown to have decreased progressively in foragers and guards.

  15. Homology differences between complete Sacbrood virus genomes from infected Apis mellifera and Apis cerana honeybees in Korea.

    Science.gov (United States)

    Reddy, Kondreddy Eswar; Yoo, Mi Sun; Kim, Young-Ha; Kim, Nam-Hee; Ramya, Mummadireddy; Jung, Ha-Na; Thao, Le Thi Bich; Lee, Hee-Soo; Kang, Seung-Won

    2016-04-01

    Sacbrood virus (SBV) represents a serious threat to the health of managed honeybees. We determined four complete SBV genomic sequences (AmSBV-Kor1, AmSBV-Kor2, AcSBV-Kor3, and AcSBV-Kor4) isolated from Apis mellifera and Apis cerana in various regions of South Korea. A phylogenetic tree was constructed from the complete genomic sequences of these Korean SBVs (KSBVs) and 21 previously reported SBV sequences from other countries. Three KSBVs (not AmSBV-Kor1) clustered with previously reported Korean genomes, but separately from SBV genomes from other countries. The KSBVs shared 90-98 % identity, and 89-97 % identity with the genomes from other countries. AmSBV-Kor1 was least similar (~90 % identity) to the other KSBVs, and was most similar to previously reported strains AmSBV-Kor21 (97 %) and AmSBV-UK (93 %). Phylogenetic analysis of the partial VP1 region sequences indicated that SBVs clustered by host species and country of origin. The KSBVs were aligned with nine previously reported complete SBV genomes and compared. The KSBVs were most different from the other genomes at the end of the 5' untranslated region and in the entire open reading frame. A SimPlot graph of the VP1 region confirmed its high variability, especially between the SBVs infecting A. mellifera and A. cerana. In this genomic region, SBVs from A. mellifera species contain an extra continuous 51-nucleotide sequence relative to the SBVs from A. cerana. This genomic diversity may reflect the adaptation of SBV to specific hosts, viral cross-infections, and the spatial distances separating the KSBVs from other SBVs.

  16. Efficiency of local Indonesia honey bees (Apis cerana L.) and stingless bee (Trigona iridipennis) on tomato (Lycopersicon esculentum Mill.) pollination.

    Science.gov (United States)

    Putra, Ramadhani Eka; Kinasih, Ida

    2014-01-01

    Tomato (Lycopersicon esculentum Mill.) is considered as one of major agricultural commodity of Indonesia farming. However, monthly production is unstable due to lack of pollination services. Common pollinator agent of tomatoes is bumblebees which is unsuitable for tropical climate of Indonesia and the possibility of alteration of local wild plant interaction with their pollinator. Indonesia is rich with wild bees and some of the species already domesticated for years with prospect as pollinating agent for tomatoes. This research aimed to assess the efficiency of local honey bee (Apis cerana L.) and stingless bee (Trigona iridipennis), as pollinator of tomato. During this research, total visitation rate and total numbers of pollinated flowers by honey bee and stingless bee were compared between them with bagged flowers as control. Total fruit production, average weight and size also measured in order to correlated pollination efficiency with quantity and quality of fruit produced. Result of this research showed that A. cerana has slightly higher rate of visitation (p>0.05) and significantly shorter handling time (p tomato flowers. However, honey bee pollinated tomato flowers more efficient pollinator than stingless bee (80.3 and 70.2% efficiency, respectively; p tomatoes were similar (p>0.05). Based on the results, it is concluded that the use of Apis cerana and Trigona spp., for pollinating tomatoes in tropical climates could be an alternative to the use of non-native Apis mellifera and bumblebees (Bombus spp.). However, more researches are needed to evaluate the cost/benefit on large-scale farming and greenhouse pollination using both bees against other bee species and pollination methods.

  17. Environmental Effects of Hydrokinetic Turbines on Fish: Desktop and Laboratory Flume Studies

    Energy Technology Data Exchange (ETDEWEB)

    Jacobson, Paul T. [Electric Power Research Institute; Amaral, Stephen V. [Alden Research Laboratory; Castro-Santos, Theodore [U.S. Geological Survey; Giza, Dan [Alden Research Laboratory; Haro, Alexander J. [U.S. Geological Survey; Hecker, George [Alden Research Laboratory; McMahon, Brian [Alden Research Laboratory; Perkins, Norman [Alden Research Laboratory; Pioppi, Nick [Alden Research Laboratory

    2012-12-31

    This collection of three reports describes desktop and laboratory flume studies that provide information to support assessment of the potential for injury and mortality of fish that encounter hydrokinetic turbines of various designs installed in tidal and river environments. Behavioral responses to turbine exposure also are investigated to support assessment of the potential for disruptions to upstream and downstream movements of fish. The studies: (1) conducted an assessment of potential injury mechanisms using available data from studies with conventional hydro turbines; (2) developed theoretical models for predicting blade strike probabilities and mortality rates; and (3) performed flume testing with three turbine designs and several fish species and size groups in two laboratory flumes to estimate survival rates and document fish behavior. The project yielded three reports which this document comprises. The three constituent documents are addressed individually below Fish Passage Through Turbines: Application of Conventional Hydropower Data to Hydrokinetic Technologies Fish passing through the blade sweep of a hydrokinetic turbine experience a much less harsh physical environment than do fish entrained through conventional hydro turbines. The design and operation of conventional turbines results in high flow velocities, abrupt changes in flow direction, relatively high runner rotational and blade speeds, rapid and significant changes in pressure, and the need for various structures throughout the turbine passageway that can be impacted by fish. These conditions generally do not occur or are not significant factors for hydrokinetic turbines. Furthermore, compared to conventional hydro turbines, hydrokinetic turbines typically produce relatively minor changes in shear, turbulence, and pressure levels from ambient conditions in the surrounding environment. Injuries and mortality from mechanical injuries will be less as well, mainly due to low rotational speeds and

  18. Deposition of PEDOT: PSS Nanoparticles as a Conductive Microlayer Anode in OLEDs Device by Desktop Inkjet Printer

    Directory of Open Access Journals (Sweden)

    S. Ummartyotin

    2011-01-01

    Full Text Available A simple microfabrication technique for delivering macromolecules and patterning microelectrode arrays using desktop inkjet printer was described. Aqueous solution of nanoparticle of poly (3,4-ethylenedioxythiophene (PEDOT doped with polystyrene sulfonic acid (PSS was prepared while its particle size, the surface tension, and the viscosity of the solution were adjusted to be suitable for deposition on a flexible cellulose nanocomposite substrate via inkjet printer. The statistical average of PEDOT: PSS particle size of 100 nm was observed. The microthickness, surface morphology, and electrical conductivity of the printed substrate were then characterized by profilometer, atomic force microscope (AFM, and four-point probe electrical measurement, respectively. The inkjet deposition of PEDOT: PSS was successfully carried out, whilst retained its transparency feature. Highly smooth surface (roughness ~23–44 nm was achieved.

  19. A study of operators' computing efficiency with special focus on the readability under different viewing angles of a desktop

    Science.gov (United States)

    Maillck, Z.; Asjad, Mohammad

    2015-09-01

    The main objective of this work is to determine the reading performance of operators' under different viewing angles of a desktop computer. The effects of text/background color, viewing distance and character size on the speed of reading were investigated. The text and/or the background color combination were varied, with constant luminance contrast. Performance was recorded in terms of words per minutes. Standard workplace design recommendations to position center of visual display terminal 15° and 40°, below horizontal eye level, were taken up for a visually intensive readability task. An orthogonal array, signal-to-noise ratio and the analysis of variance were carried out to investigate the above mentioned operating parameters to determine optimum readability performance. The results suggested that performance was better at 15° viewing angle as compared to 40°.

  20. A tropical marine microbial natural products geobibliography as an example of desktop exploration of current research using web visualisation tools.

    Science.gov (United States)

    Mukherjee, Joydeep; Llewellyn, Lyndon E; Evans-Illidge, Elizabeth A

    2008-01-01

    Microbial marine biodiscovery is a recent scientific endeavour developing at a time when information and other technologies are also undergoing great technical strides. Global visualisation of datasets is now becoming available to the world through powerful and readily available software such as Worldwind, ArcGIS Explorer and Google Earth. Overlaying custom information upon these tools is within the hands of every scientist and more and more scientific organisations are making data available that can also be integrated into these global visualisation tools. The integrated global view that these tools enable provides a powerful desktop exploration tool. Here we demonstrate the value of this approach to marine microbial biodiscovery by developing a geobibliography that incorporates citations on tropical and near-tropical marine microbial natural products research with Google Earth and additional ancillary global data sets. The tools and software used are all readily available and the reader is able to use and install the material described in this article.

  1. PileLineGUI: a desktop environment for handling genome position files in next-generation sequencing studies.

    Science.gov (United States)

    López-Fernández, Hugo; Glez-Peña, Daniel; Reboiro-Jato, Miguel; Gómez-López, Gonzalo; Pisano, David G; Fdez-Riverola, Florentino

    2011-07-01

    Next-generation sequencing (NGS) technologies are making sequence data available on an unprecedented scale. In this context, new catalogs of Single Nucleotide Polymorphism and mutations generated by resequencing studies are usually stored in genome position files (e.g. Variant Call Format, SAMTools pileup, BED, GFF) comprising of large lists of genomic positions, which are difficult to handle by researchers. Here, we present PileLineGUI, a novel desktop application primarily designed for manipulating, browsing and analysing genome position files (GPF), with specific support to somatic mutation finding studies. The developed tool also integrates a new genome browser module specially designed for inspecting GPFs. PileLineGUI is free, multiplatform and designed to be intuitively used by biomedical researchers. PileLineGUI is available at: http://sing.ei.uvigo.es/pileline/pilelinegui.html.

  2. Effects of Desktop Virtual Reality Environment Training on State Anxiety and Vocational Identity Scores among Persons with Disabilities during Job Placement

    Science.gov (United States)

    Washington, Andre Lamont

    2013-01-01

    This study examined how desktop virtual reality environment training (DVRET) affected state anxiety and vocational identity of vocational rehabilitation services consumers during job placement/job readiness activities. It utilized a quantitative research model with a quasi-experimental pretest-posttest design plus some qualitative descriptive…

  3. From Desktop Toy to Educational Aid: Neo Magnets as an Alternative to Ball-and-Stick Models in Representing Carbon Fullerenes

    Science.gov (United States)

    Kao, Jacqueline Y.; Yang, Min-Han; Lee, Chi-Young

    2015-01-01

    Neo magnets are neodymium magnet beads that have been marketed as a desktop toy. We proposed using neo magnets as an alternative building block to traditional ball-and-stick models to construct carbon allotropes, such as fullerene and various nanocone structures. Due to the lack of predetermined physical connections, the versatility of carbon…

  4. Telephone Interpreter Services (TIS)-Asian and Pacific Islander (API) Language Fiscal Year Quarterly Dataset

    Data.gov (United States)

    Social Security Administration — This dataset displays our quarterly national TIS call volume for over 45 API languages for the current fiscal year. A fiscal year runs from October through September...

  5. Telephone Interpreter Services (TIS)-Asian and Pacific Islander (API) Language Yearly Dataset

    Data.gov (United States)

    Social Security Administration — This dataset displays our national TIS call volume for over 45 API languages for the last three fiscal years. A fiscal year runs from October through September. We...

  6. Bilingual education, indigenous language and culture: the case of Apyãwa Tapirapé

    Directory of Open Access Journals (Sweden)

    Maria Gorete Neto

    Full Text Available Bilingual schools are recognized as an important resource to increase the chances of language survival but in many cases have proven to be ineffective. Within the Apyãwa Tapirapé Indian Tribe (central Brazil, an effective bilingual school does exist; however, this study shows that even a successful school brings complications for the community. Audio-recorded interviews, in which teachers and leaders discuss their bilingual school and its consequences for the Apyãwa Tapirapé people, reveal that they feel that the school has changed the Apyãwa Tapirapé lifestyle in both negative and positive ways. A continuous evaluation and ongoing reconstruction of educational aspects is proposed as a way to both attend to the needs and to relieve the worries of groups like the Apyãwa Tapirapé with respect to the impact of their school on the community.

  7. A review on the taste masking of bitter APIs: hot-melt extrusion (HME) evaluation.

    Science.gov (United States)

    Maniruzzaman, Mohammed; Boateng, Joshua S; Chowdhry, Babur Z; Snowden, Martin J; Douroumis, Dennis

    2014-02-01

    The majority of active pharmaceutical ingredients (APIs) found in oral dosage forms have a bitter taste. Masking the unpleasant taste of bitter, APIs is a major challenge in the development of such oral dosage forms. Taste assessment is an important quality-control parameter for evaluating taste-masked formulations of any new molecular entity. Hot-melt extrusion (HME) techniques, have very recently, been accepted from an industrial compliance viewpoint in relation to both manufacturing operations and development of pharmaceuticals. HME achieves taste masking of bitter APIs via various mechanisms such as the formation of solid dispersions and inter-molecular interactions and this has led to its wide-spread use in pharmaceutical formulation research. In this article, the uses of various taste evaluation methods and HME as continuous processing techniques for taste masking of bitter APIs used for the oral delivery of drugs are reviewed.

  8. Candida albicans response to spaceflight (NASA STS-115) --- GSM1231690_Slide_43 API

    Data.gov (United States)

    National Aeronautics and Space Administration — A fully queryable REST API with JSON, XML, and CSV output as well as inline, runable examples using data from the transcriptional profiling and phenotypic...

  9. Dosis Letal Media (DL50 de algunos aceites esenciales y biocidas efectivos para el control de Ascosphaera apis en Apis mellifera L. - Median Lethal Dose (LD50 of some essential oils and biocides effective for the control of Ascosphaera apis on Apis mellifera L

    Directory of Open Access Journals (Sweden)

    Albo, Graciela N

    2010-10-01

    Full Text Available ResumenLa ascofaeriosis o cría yesificada, es una enfermedad de la abeja melífera (Apis mellifera L. causada por el hongo Ascosphaera apis que produce la momificación de las larvas. Los aceites esenciales poseen efectos antimicrobianos y han sido utilizados para el control de cría yesificada. Por otra parte, a nivel mundial se han probado gran cantidad de productos de síntesis, pero ninguno ha resultado 100 % eficaz. SummaryChalkbrood is a disease of the honeybee (Apis mellifera L caused by the fungus Ascosphaera apis that transforms larvae into mummies. Essential oils have showed antimicrobial activity and have been used in the control of chalkbrood. Moreover, world-wide, great number of synthesized products have been assayed but no one has resulted 100% effective.

  10. S E- GEOD-50881 Study Samples --- Candida albicans response to spaceflight (NASA STS-115) API

    Data.gov (United States)

    National Aeronautics and Space Administration — A fully queryable REST API with JSON, XML, and CSV output as well as inline, runable examples using data from the transcriptional profiling and phenotypic...

  11. A E- GEOD-50881 Gene Chip Assay --- Candida albicans response to spaceflight (NASA STS-115) API

    Data.gov (United States)

    National Aeronautics and Space Administration — A fully queryable REST API with JSON, XML, and CSV output as well as inline, runable examples using data from the transcriptional profiling and phenotypic...

  12. BUILDING MODEL ANALYSIS APPLICATIONS WITH THE JOINT UNIVERSAL PARAMETER IDENTIFICATION AND EVALUATION OF RELIABILITY (JUPITER) API

    Science.gov (United States)

    The open-source, public domain JUPITER (Joint Universal Parameter IdenTification and Evaluation of Reliability) API (Application Programming Interface) provides conventions and Fortran-90 modules to develop applications (computer programs) for analyzing process models. The input ...

  13. Three-dimensional model of the honeybee venom allergen Api m 7: structural and functional insights.

    Science.gov (United States)

    Georgieva, Dessislava; Greunke, Kerstin; Betzel, Christian

    2010-06-01

    Api m 7 is one of the major protease allergens of the honeybee venom. It consists of a serine protease-like (SPL) and a CUB domain. The knowledge about the structure and function of Api m 7 is limited mainly to its amino acid sequence. Three-dimensional models of the two structural domains were constructed using their amino acid sequences and the crystallographic coordinates of prophenoloxidase-activating factor (PPAF-II) as a template for the SPL domain and the coordinates of porcine spermadhesin PSP-II for the CUB domain. The structural organization of Api m 7 suggests that the CUB domain is involved in interactions with natural substrates while the SPL domain probably activates zymogens. IgE epitopes and antigenic sites were predicted. Api m 7 shows structural and functional similarity to the members of the PPAF-II family. Possible substrates, function and evolution of the enzyme are discussed in the paper.

  14. Antagonistic Effect of Gut Bacteria in the Hybrid Carniolan Honey Bee, Apis Mellifera Carnica, Against Ascosphaera Apis, the Causal Organism of Chalkbrood Disease

    Directory of Open Access Journals (Sweden)

    Omar Mohamed O. M.

    2014-06-01

    Full Text Available The objective of this study was to isolate and characterize bacterial strains associated with the gut of the hybrid Carniolan honey bee, Apis mellifera carnica, and to determine their in vitro and in vivo potential against Ascosphaera apis, the causal organism of chalkbrood disease, with the purpose of exploring feasible biological control. Six bacterial strains were isolated from healthy worker honey bees by culture-dependent methods. Six fungal strains (A3, A4, A7, A8, A9, and A15 of A. apis were isolated from larvae suffering from chalkbrood disease on Yeast-Glucose-Starch agar (YGPSA medium. All bacteria were identified by a combination of morphology, Gram stain, and 16S rRNA sequence analysis, and fungal strains were identified by morphology and 5.8S rRNA. In vitro and in vivo inhibition assays were carried out to determine the ability of bacterial isolates to inhibit A. apis, the causal agent of chalkbrood disease. The analysis of 16S rRNA sequences revealed that four bacterial strains (B2, B4, B10, and B100 belong to Bacillus subtilis species, and two strains (P1 and P5 belong to Pseudomonas fluorescence. Significant differences in antagonistic activity of all bacterial strains were observed. B. subtilis isolate B2 showed the highest antagonistic activity, as measured by the inhibition zone against A. apis, followed by the P1 strain of P. fluorescence. SEM analysis also supports the antagonistic activity of these bacteria against A. apis. This study provides a theoretical basis for biological control of honey bee chalkbrood disease.

  15. Revoke and Let Live: A Secure Key Revocation API for Cryptographic Devices

    OpenAIRE

    Cortier, Véronique; Steel,Graham; Wiedling, Cyrille

    2012-01-01

    While extensive research addresses the problem of establishing session keys through cryptographic protocols, relatively little work has appeared addressing the problem of revocation and update of long term keys. We present an API for symmetric key management on embedded devices that supports revocation and prove security properties design in the symbolic model of cryptography. Our API supports two modes of revocation: a passive mode where keys have an expiration time, and an active mode where...

  16. Sensitivity Analysis of Fatigue Crack Growth Model for API Steels in Gaseous Hydrogen

    Science.gov (United States)

    Amaro, Robert L; Rustagi, Neha; Drexler, Elizabeth S; Slifka, Andrew J

    2014-01-01

    A model to predict fatigue crack growth of API pipeline steels in high pressure gaseous hydrogen has been developed and is presented elsewhere. The model currently has several parameters that must be calibrated for each pipeline steel of interest. This work provides a sensitivity analysis of the model parameters in order to provide (a) insight to the underlying mathematical and mechanistic aspects of the model, and (b) guidance for model calibration of other API steels. PMID:26601024

  17. Sensitivity Analysis of Fatigue Crack Growth Model for API Steels in Gaseous Hydrogen.

    Science.gov (United States)

    Amaro, Robert L; Rustagi, Neha; Drexler, Elizabeth S; Slifka, Andrew J

    2014-01-01

    A model to predict fatigue crack growth of API pipeline steels in high pressure gaseous hydrogen has been developed and is presented elsewhere. The model currently has several parameters that must be calibrated for each pipeline steel of interest. This work provides a sensitivity analysis of the model parameters in order to provide (a) insight to the underlying mathematical and mechanistic aspects of the model, and (b) guidance for model calibration of other API steels.

  18. Using DLL as Interface between API an VC#.NET Applications

    Directory of Open Access Journals (Sweden)

    Marian DARDALA

    2006-01-01

    Full Text Available This paper presents a solution for using complex Win32API data structures and functions in Visual C# .NET applications. We built DLL (Dynamic Link Library to manage the API functions and data structures and we used DLL modules in a C# application. This is an easier working way compared with the traditional way of importing and managing API’s functions in C# programs.

  19. Use of surfactants as plasticizers in preparing solid dispersions of poorly soluble API: selection of polymer-surfactant combinations using solubility parameters and testing the processability.

    Science.gov (United States)

    Ghebremeskel, Alazar N; Vemavarapu, Chandra; Lodaya, Mayur

    2007-01-10

    Formation of solid dispersions as a means to enhance the dissolution rate of poorly soluble Active pharmaceutical ingredients (APIs) typically employs hydrophilic polymer systems and surfactants. While the utility of the surfactant systems in solubilization is well known, the secondary effects of the same on processing and subsequent physical stability of the solid dispersions needs to be studied further. Physical blends of the poorly soluble API and hydrophilic polymers such as PVP-K30, Plasdone-S630, HPMC-E5, HPMCAS, and Eudragit L100 with mass ratio 1:1 were prepared. The surfactants tested in this study included Tween-80, Docusate sodium, Myrj-52, Pluronic-F68 and SLS. Thermal analysis of the API-polymer-surfactant blends suggested that the surfactants caused solvation/plasticization, manifesting in reduction of (i) the melting (T(m)) of API (ii) T(g) of the polymers and (iii) the combined T(g) of the solid dispersion formed from quench cooling. Explanation of these effects of surfactants is attempted based on their physical state (at the temperature of interest), HLB values and similarity of their solubility parameter values with respect to drug-polymer systems. Furthermore, extruded matrices containing different API-polymer (PVP-K30, Plasdone-S630, and HPMC-E5) mixtures prepared with and without surfactants, were produced by feeding the powder blend through a hot-melt extruder. The melt viscosity of the polymer blends was assessed by torque rheometry using a Haake Rheomix. The physicochemical properties of the extruded API-polymer-surfactant were characterized by differential scanning calorimetry, X-ray diffraction, Raman spectroscopy, and polarized microscopy. The results demonstrated that the glass transition temperature of the carrier polymers decreased as direct result of the surfactants in the extrudate, due to an increase in the chain mobility of polymers. A decrease in the melt viscosity was seen due to a plasticization of the polymer. The drug release

  20. Micro-scale prediction method for API-solubility in polymeric matrices and process model for forming amorphous solid dispersion by hot-melt extrusion.

    Science.gov (United States)

    Bochmann, Esther S; Neumann, Dirk; Gryczke, Andreas; Wagner, Karl G

    2016-10-01

    A new predictive micro-scale solubility and process model for amorphous solid dispersions (ASDs) by hot-melt extrusion (HME) is presented. It is based on DSC measurements consisting of an annealing step and a subsequent analysis of the glass transition temperature (Tg). The application of a complex mathematical model (BCKV-equation) to describe the dependency of Tg on the active pharmaceutical ingredient (API)/polymer ratio, enables the prediction of API solubility at ambient conditions (25°C). Furthermore, estimation of the minimal processing temperature for forming ASDs during HME trials could be defined and was additionally confirmed by X-ray powder diffraction data. The suitability of the DSC method was confirmed with melt rheological trials (small amplitude oscillatory system). As an example, ball milled physical mixtures of dipyridamole, indomethacin, itraconazole and nifedipine in poly(vinylpyrrolidone-co-vinylacetate) (copovidone) and polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer (Soluplus®) were used.

  1. Hot-stage microscopy for determination of API particles in a formulated tablet.

    Science.gov (United States)

    Simek, Michal; Grünwaldová, Veronika; Kratochvíl, Bohumil

    2014-01-01

    Although methods exist to readily determine the particle size distribution (PSD) of an active pharmaceutical ingredient (API) before its formulation into a final product, the primary challenge is to develop a method to determine the PSD of APIs in a finished tablet. To address the limitations of existing PSD methods, we used hot-stage microscopy to observe tablet disintegration during temperature change and, thus, reveal the API particles in a tablet. Both mechanical and liquid disintegration were evaluated after we had identified optimum milling time for mechanical disintegration and optimum volume of water for liquid disintegration. In each case, hot-stage micrographs, taken before and after the API melting point, were compared with image analysis software to obtain the PSDs. Then, the PSDs of the APIs from the disintegrated tablets were compared with the PSDs of raw APIs. Good agreement was obtained, thereby confirming the robustness of our methodology. The availability of such a method equips pharmaceutical scientists with an in vitro assessment method that will more reliably determine the PSD of active substances in finished tablets.

  2. The Matchmaker Exchange API: automating patient matching through the exchange of structured phenotypic and genotypic profiles.

    Science.gov (United States)

    Buske, Orion J; Schiettecatte, François; Hutton, Benjamin; Dumitriu, Sergiu; Misyura, Andriy; Huang, Lijia; Hartley, Taila; Girdea, Marta; Sobreira, Nara; Mungall, Chris; Brudno, Michael

    2015-10-01

    Despite the increasing prevalence of clinical sequencing, the difficulty of identifying additional affected families is a key obstacle to solving many rare diseases. There may only be a handful of similar patients worldwide, and their data may be stored in diverse clinical and research databases. Computational methods are necessary to enable finding similar patients across the growing number of patient repositories and registries. We present the Matchmaker Exchange Application Programming Interface (MME API), a protocol and data format for exchanging phenotype and genotype profiles to enable matchmaking among patient databases, facilitate the identification of additional cohorts, and increase the rate with which rare diseases can be researched and diagnosed. We designed the API to be straightforward and flexible in order to simplify its adoption on a large number of data types and workflows. We also provide a public test data set, curated from the literature, to facilitate implementation of the API and development of new matching algorithms. The initial version of the API has been successfully implemented by three members of the Matchmaker Exchange and was immediately able to reproduce previously identified matches and generate several new leads currently being validated. The API is available at https://github.com/ga4gh/mme-apis.

  3. Integration of Environmental Sensors with BIM: case studies using Arduino, Dynamo, and the Revit API

    Directory of Open Access Journals (Sweden)

    Kensek, K. M.

    2014-12-01

    Full Text Available This paper investigates the feasibility of connecting environmental sensors such as light, humidity, or CO2 receptors to a building information model (BIM. A base case was created in Rhino; using Grasshopper and Firefly, a simple digital model responded to lighting-levels detected by a photoresistor on an Arduino board. The case study was duplicated using Revit Architecture, a popular BIM software, and Dynamo, a visual programming environment, in an innovative application. Another case study followed a similar procedure by implementing the Revit API directly instead of using Dynamo. Then the process was reversed to demonstrate that not only could data could be sent from sensors to change the 3D model, but changes to parameters of a 3D model could effect a physical model through the use of actuators. It is intended that these virtual/physical prototypes could be used as the basis for testing intelligent façade systems before constructing full size mock-ups.Este estudio investiga la posibilidad de conectar sensores ambientales como de luz, humedad, o dióxido de carbono con un modelo de información de un edificio (siglas BIM en inglés. Un caso base fue creado en Rhino; usando Grasshopper and Firefly, donde un simple modelo digital respondió a niveles de luz detectados por un foto resistor en una tarjeta Arduino. El caso de estudio fue duplicado usando Revit Architecture, una herramienta popular en BIM, y Dynamo, un ambiente de programación gráfica, en una creativa aplicación. Un segundo caso de estudio siguió un procedimiento similar implementando Revit API directamente en vez de usar Dynamo. Entonces el proceso fue revertido para demostrar que no solamente la información podría ser enviada desde sensores para cambiar el modelo tridimensional, pero cambios en los parámetros de un modelo tridimensional podrían afectar un modelo físico mediante el uso de actuadores. Se espera que esos modelos virtuales puedan ser usados como base para

  4. Hardness and microstructural characterization of API 5L X70 steel pipes welded by HF/ERW process; Caracterizacao microestrutural e de dureza em tubos de aco API 5L X70 soldados pelo processo HF/ERW

    Energy Technology Data Exchange (ETDEWEB)

    Calcada, Mauricio Vieira; Voorwald, Herman Jacobus Cornelis; Nascimento, Marcelino Pereira do [UNESP, Guaratingueta, SP (Brazil). Faculdade de Engenharia

    2010-07-01

    The materials that stand in the manufacture of steel pipes are called API, that should have, high mechanical resistance, high corrosion resistance, high fatigue resistance, good weldability, and other properties. Thus, the purpose of this project was to evaluate the microstructure and hardness of welded joints by the HF/ERW process of API 5L X70 steel pipes. The microstructural analysis was performed using a surface finish with grit sizes from 220 to 25 {mu}m e polishing with diamond paste from 9 {mu}m to 0.05 {mu}m; the revelation was made with 3% Nital attack. The Vickers hardness was performed across the welded joint by 33 points to indentation. The results were: 80.5 {+-} 3.4% of ferrite and 19.5 {+-} 3.4% of perlite for microanalysis. As for hardness, the values were: 215.69 HV10 for weld line, 218.65 HV10 for ZTA and 218.95 HV10 for base metal. (author)

  5. Use of a quality-by-design approach to justify removal of the HPLC weight % assay from routine API stability testing protocols.

    Science.gov (United States)

    Skrdla, Peter J; Wang, Tao; Antonucci, Vincent; Dowling, Thomas; Ge, Zhihong; Ellison, Dean; Curran, John; Mohan, Ganapathy; Wyvratt, Jean

    2009-12-01

    Due to the high method variability (typically > or = 0.5%, based on a literature survey and internal Merck experience) encountered in the HPLC weight percent (%) assays of various active pharmaceutical ingredients (APIs), it is proposed that the routine use of the test in stability studies should be discouraged on the basis that it is frequently not sufficiently precise to yield results that are stability-indicating. The high method variability of HPLC weight % methods is not consistent with the current ICH practice of reporting impurities/degradation products down to the 0.05% level, and it can lead to erroneous out-of-specification (OOS) results that are due to experimental error and are not attributable to API degradation. For the vast majority of cases, the HPLC impurity profile provides much better (earlier and more sensitive) detection of low-level degradation products. Based on these observations, a Quality-by-Design (QbD) approach is proposed to phase out the HPLC weight % assay from routine API stability testing protocols.

  6. 桌面3D打印机工作台贴面材料分析%Analysis of the Cover Material of the Desktop 3D Printer

    Institute of Scientific and Technical Information of China (English)

    关雷; 史子木; 武坤

    2016-01-01

    3D printing technology, also known as rapid prototyping, is an emerging technology. The desktop 3D printer based on fused deposition modeling (FDM) technology is increasingly used. In order to firmly coat printing consumables on workbench, some materials adhered easily are used for the workbench surface of 3D printer. According to the different printing consumables, different covering materials should be used. In this article, the performance, method of use and range of application, etc. of cover materials were analyzed. In addition, the advantages and disadvantages of the cover materials were also analyzed, with printing PLA as an example.%3D打印技术也称为快速成型,是一门新兴的技术。其中基于融熔沉积技术的桌面3D打印机应用日益广泛。为了使打印材料牢固的涂覆在打印机工作台表面,需要将一些利于粘附的材料贴附到3D打印机工作台表面。根据不同的打印耗材,应使用不同的贴面材料。文章分析了几种贴面材料的性能,使用方法,适用范围。并以使用PLA (聚乳酸)线材进行3D打印为例,分析了几种工作台贴面材料的优缺点。

  7. Mating flights select for symmetry in honeybee drones (Apis mellifera).

    Science.gov (United States)

    Jaffé, Rodolfo; Moritz, Robin F A

    2010-03-01

    Males of the honeybee (Apis mellifera) fly to specific drone congregation areas (DCAs), which virgin queens visit in order to mate. From the thousands of drones that are reared in a single colony, only very few succeed in copulating with a queen, and therefore, a strong selection is expected to act on adult drones during their mating flights. In consequence, the gathering of drones at DCAs may serve as an indirect mate selection mechanism, assuring that queens only mate with those individuals having a better flight ability and a higher responsiveness to the queen's visual and chemical cues. Here, we tested this idea relying on wing fluctuating asymmetry (FA) as a measure of phenotypic quality. By recapturing marked drones at a natural DCA and comparing their size and FA with a control sample of drones collected at their maternal hives, we were able to detect any selection on wing size and wing FA occurring during the mating flights. Although we found no solid evidence for selection on wing size, wing FA was found to be significantly lower in the drones collected at the DCA than in those collected at the hives. Our results demonstrate the action of selection during drone mating flights for the first time, showing that developmental stability can influence the mating ability of honeybee drones. We therefore conclude that selection during honeybee drone mating flights may confer some fitness advantages to the queens.

  8. Energetic feedings influence beeswax production by Apis mellifera L. honeybees

    Directory of Open Access Journals (Sweden)

    Marcela Pedraza Carrillo

    2015-02-01

    Full Text Available The effect of different types of energy feeding (sugar syrup, inverted sugar and juice of sugar-cane on beeswax production and its economic feasibility are evaluated. Twenty beehives of Africanized Apis mellifera were selected, and five were used for each type of feeding. The treatments were T1 (sugar-cane juice, T2 (sugar syrup and T3 (inverted sugar. Feedings was provided by Boardman feeders and the amount was adjusted according to consumption. A layer of beeswax was manually set up into the honeybee nest and beeswax built area was measured weekly. Total reducing sugar, calorimetry, dry matter and ashes of all feedings were analyzed. Data were analyzed by analysis of variance with Tukey’s test to determine differences among averages. The average consumption of inverted sugar was significantly lower than that of other treatments. The highest beeswax production average occurred in the sugar syrup treatment. The highest average of ashes, dry matter and reducing sugar occurred, respectively, in sugar-cane juice, inverted sugar and sugar syrup. Sugar syrup may be an alternative energy source for beeswax production, although sugar-cane juice may be more profitable.

  9. The Influence of Niobium on SSC Resistance in API Steels

    Energy Technology Data Exchange (ETDEWEB)

    Malina, J.; Malina, M.; Novosel-Radovic, V. [Zagreb Univ., Faculty of Metallurgy (Croatia)

    2004-07-01

    Full text of publication follows: Oil country tubular goods are often exposed to aggressive sour environments in oil wells where H{sub 2}S promotes sulfide stress cracking, SSC. This is one of the most dangerous corrosion phenomena characterized by unpredictable and sudden cracking of steel constructions in service. SSC results in a variety of fracture features having a common relationship to the presence of hydrogen in metal and therefore it belongs to hydrogen embrittlement phenomena, HE. For the production of sulfide stress cracking resistant (SSC) tubing from steels included in Group 3 of API Specification 5CT, in this study two experimental Cr-Mo steels (without niobium and with niobium microalloyed) were tested. The influence of Nb precipitates in pipeline steels on the sensitivity to sulfide stress cracking was examined in laboratory experiments using three point bent beam tests. High mechanical properties were achieved through quenching and tempering procedures. Better corrosion resistance of Nb-containing steel is the consequence of microstructural parameters obtained through strengthening mechanism with microalloying element. Besides the usual mechanical, metallographic, SEM and TEM analyses, as complementary method the X-ray diffraction was used. It was revealed that tetragonality of crystal lattice, dislocation density and residual stresses are in good correlation with Sc-vales from corrosion tests. Nb precipitates (especially niobium carbides) have beneficial influence when producing the steels with low sensitivity to SSC. (authors)

  10. Nosema Tolerant Honeybees (Apis mellifera) Escape Parasitic Manipulation of Apoptosis

    Science.gov (United States)

    Kurze, Christoph; Le Conte, Yves; Dussaubat, Claudia; Erler, Silvio; Kryger, Per; Lewkowski, Oleg; Müller, Thomas; Widder, Miriam; Moritz, Robin F. A.

    2015-01-01

    Apoptosis is not only pivotal for development, but also for pathogen defence in multicellular organisms. Although numerous intracellular pathogens are known to interfere with the host’s apoptotic machinery to overcome this defence, its importance for host-parasite coevolution has been neglected. We conducted three inoculation experiments to investigate in the apoptotic respond during infection with the intracellular gut pathogen Nosema ceranae, which is considered as potential global threat to the honeybee (Apis mellifera) and other bee pollinators, in sensitive and tolerant honeybees. To explore apoptotic processes in the gut epithelium, we visualised apoptotic cells using TUNEL assays and measured the relative expression levels of subset of candidate genes involved in the apoptotic machinery using qPCR. Our results suggest that N. ceranae reduces apoptosis in sensitive honeybees by enhancing inhibitor of apoptosis protein-(iap)-2 gene transcription. Interestingly, this seems not be the case in Nosema tolerant honeybees. We propose that these tolerant honeybees are able to escape the manipulation of apoptosis by N. ceranae, which may have evolved a mechanism to regulate an anti-apoptotic gene as key adaptation for improved host invasion. PMID:26445372

  11. Nosema Tolerant Honeybees (Apis mellifera Escape Parasitic Manipulation of Apoptosis.

    Directory of Open Access Journals (Sweden)

    Christoph Kurze

    Full Text Available Apoptosis is not only pivotal for development, but also for pathogen defence in multicellular organisms. Although numerous intracellular pathogens are known to interfere with the host's apoptotic machinery to overcome this defence, its importance for host-parasite coevolution has been neglected. We conducted three inoculation experiments to investigate in the apoptotic respond during infection with the intracellular gut pathogen Nosema ceranae, which is considered as potential global threat to the honeybee (Apis mellifera and other bee pollinators, in sensitive and tolerant honeybees. To explore apoptotic processes in the gut epithelium, we visualised apoptotic cells using TUNEL assays and measured the relative expression levels of subset of candidate genes involved in the apoptotic machinery using qPCR. Our results suggest that N. ceranae reduces apoptosis in sensitive honeybees by enhancing inhibitor of apoptosis protein-(iap-2 gene transcription. Interestingly, this seems not be the case in Nosema tolerant honeybees. We propose that these tolerant honeybees are able to escape the manipulation of apoptosis by N. ceranae, which may have evolved a mechanism to regulate an anti-apoptotic gene as key adaptation for improved host invasion.

  12. Cytosine modifications in the honey bee (Apis mellifera worker genome

    Directory of Open Access Journals (Sweden)

    Erik Magne Koscielniak Rasmussen

    2015-02-01

    Full Text Available Epigenetic changes enable genomes to respond to changes in the environment, such as altered nutrition, activity, or social setting. Epigenetic modifications, thereby, provides a source of phenotypic plasticity in many species. The honey bee (Apis mellifera uses nutritionally sensitive epigenetic control mechanisms in the development of the royal caste (queens and the workers. The workers are functionally sterile females that can take on a range of distinct physiological and/or behavioral phenotypes in response to environmental changes. Honey bees have a wide repertoire of epigenetic mechanisms which, as in mammals, includes cytosine methylation, hydroxymethylated cytosines, together with the enzymatic machinery responsible for these cytosine modifications. Current data suggests that honey bees provide an excellent system for studying the social repertoire of the epigenome. In this review, we elucidate what is known so far about the honey bee epigenome and its mechanisms. Our discussion includes what may distinguish honey bees from other model animals, how the epigenome can influence worker behavioral task separation, and how future studies can answer central questions about the role of the epigenome in social behavior.

  13. Activity of telomerase and telomeric length in Apis mellifera.

    Science.gov (United States)

    Korandová, Michala; Frydrychová, Radmila Čapková

    2016-06-01

    Telomerase is an enzyme that adds repeats of DNA sequences to the ends of chromosomes, thereby preventing their shortening. Telomerase activity is associated with proliferative status of cells, organismal development, and aging. We report an analysis of telomerase activity and telomere length in the honeybee, Apis mellifera. Telomerase activity was found to be regulated in a development and caste-specific manner. During the development of somatic tissues of larval drones and workers, telomerase activity declined to 10 % of its level in embryos and remained low during pupal and adult stages but was upregulated in testes of late pupae, where it reached 70 % of the embryo level. Upregulation of telomerase activity was observed in the ovaries of late pupal queens, reaching 160 % of the level in embryos. Compared to workers and drones, queens displayed higher levels of telomerase activity. In the third larval instar of queens, telomerase activity reached the embryo level, and an enormous increase was observed in adult brains of queens, showing a 70-fold increase compared to a brain of an adult worker. Southern hybridization of terminal TTAGG fragments revealed a high variability of telomeric length between different individuals, although the same pattern of hybridization signals was observed in different tissues of each individual.

  14. Mating flights select for symmetry in honeybee drones ( Apis mellifera)

    Science.gov (United States)

    Jaffé, Rodolfo; Moritz, Robin F. A.

    2010-03-01

    Males of the honeybee ( Apis mellifera) fly to specific drone congregation areas (DCAs), which virgin queens visit in order to mate. From the thousands of drones that are reared in a single colony, only very few succeed in copulating with a queen, and therefore, a strong selection is expected to act on adult drones during their mating flights. In consequence, the gathering of drones at DCAs may serve as an indirect mate selection mechanism, assuring that queens only mate with those individuals having a better flight ability and a higher responsiveness to the queen’s visual and chemical cues. Here, we tested this idea relying on wing fluctuating asymmetry (FA) as a measure of phenotypic quality. By recapturing marked drones at a natural DCA and comparing their size and FA with a control sample of drones collected at their maternal hives, we were able to detect any selection on wing size and wing FA occurring during the mating flights. Although we found no solid evidence for selection on wing size, wing FA was found to be significantly lower in the drones collected at the DCA than in those collected at the hives. Our results demonstrate the action of selection during drone mating flights for the first time, showing that developmental stability can influence the mating ability of honeybee drones. We therefore conclude that selection during honeybee drone mating flights may confer some fitness advantages to the queens.

  15. Resistance rather than tolerance explains survival of savannah honeybees (Apis mellifera scutellata) to infestation by the parasitic mite Varroa destructor.

    Science.gov (United States)

    Strauss, Ursula; Dietemann, Vincent; Human, Hannelie; Crewe, Robin M; Pirk, Christian W W

    2016-03-01

    Varroa destructor is considered the most damaging parasite affecting honeybees (Apis mellifera L.). However, some honeybee populations such as the savannah honeybee (Apis mellifera scutellata) can survive mite infestation without treatment. It is unclear if survival is due to resistance mechanisms decreasing parasite reproduction or to tolerance mechanisms decreasing the detrimental effects of mites on the host. This study investigates both aspects by quantifying the reproductive output of V. destructor and its physiological costs at the individual host level. Costs measured were not consistently lower when compared with susceptible honeybee populations, indicating a lack of tolerance. In contrast, reproduction of V. destructor mites was distinctly lower than in susceptible populations. There was higher proportion of infertile individuals and the reproductive success of fertile mites was lower than measured to date, even in surviving populations. Our results suggest that survival of savannah honeybees is based on resistance rather than tolerance to this parasite. We identified traits that may be useful for breeding programmes aimed at increasing the survival of susceptible populations. African honeybees may have benefited from a lack of human interference, allowing natural selection to shape a population of honeybees that is more resistant to Varroa mite infestation.

  16. Western honeybee drones and workers (Apis mellifera ligustica) have different olfactory mechanisms than eastern honeybees (Apis cerana cerana).

    Science.gov (United States)

    Woltedji, Dereje; Song, Feifei; Zhang, Lan; Gala, Alemayehu; Han, Bin; Feng, Mao; Fang, Yu; Li, Jianke

    2012-09-07

    The honeybees Apis mellifera ligustica (Aml) and Apis cerana cerana (Acc) are two different western and eastern bee species that evolved in distinct ecologies and developed specific antennal olfactory systems for their survival. Knowledge of how their antennal olfactory systems function in regards to the success of each respective bee species is scarce. We compared the antennal morphology and proteome between respective sexually mature drones and foraging workers of both species using a scanning electron microscope, two-dimensional electrophoresis, mass spectrometry, bioinformatics, and quantitative real-time polymerase chain reaction. Despite the general similarities in antennal morphology of the drone and worker bees between the two species, a total of 106 and 100 proteins altered their expression in the drones' and the workers' antennae, respectively. This suggests that the differences in the olfactory function of each respective bee are supported by the change of their proteome. Of the 106 proteins that altered their expression in the drones, 72 (68%) and 34 (32%) were overexpressed in the drones of Aml and Acc, respectively. The antennae of the Aml drones were built up by the highly expressed proteins that were involved in carbohydrate metabolism and energy production, molecular transporters, antioxidation, and fatty acid metabolism in contrast to the Acc drones. This is believed to enhance the antennal olfactory functions of the Aml drones as compared to the Acc drones during their mating flight. Likewise, of the 100 proteins with expression changes between the worker bees of the two species, 67% were expressed in higher levels in the antennae of Aml worker contrasting to 33% in the Acc worker. The overall higher expressions of proteins related to carbohydrate metabolism and energy production, molecular transporters, and antioxidation in the Aml workers compared with the Acc workers indicate the Aml workers require more antennal proteins for their olfactory

  17. The construction of prokaryotic expression system for human Api6 fusion protein%人Api6融合蛋白原核表达系统的构建

    Institute of Scientific and Technical Information of China (English)

    方严; 练雪梅

    2011-01-01

    Objective:To further study the pathophysiological function of human Api6 fusion protein expression using a prokaryotic expression system. Methods: Api6 cDNA was inserted into ppSUMO vector to form recombinant plasmid pp-SUMO-Api6;recombinant plasmid ppSUMO-Api6 was trans-formed into prokaryotic expression host E.coli Rosetta;prokaryotic expression method was optimized to induce expression of recombi-nant protein Api6 in different conditions of E.coli density,temperature,IPTG concentration and induction time;recombinant protein Api6 was identified by Western blot. Results:The recombinant plasmid ppSUMO-Api6 was successfully constructed;the recombinant protein Api6 was successfully induced,and the expression of recombinant protein ppSUMO-Api6 from the prokaryotic expression system was optimized in the condition of OD600=0.5-0.8,16℃,0.5 mmol/L IPTG and 16 h induction.Conclusion:Recombinant plasmid ppSUMO-Api6 was converted into the prokaryotic expression host E.coli Rosetta to get the recombinant strain ppSUMO-Api6-Rosetta.Recombinant protein ppSUMO-Api6 was expressed using a prokaryotic expression system at the optimal expression conditions.%目的:本研究拟采用蛋白原核表达的方法,诱导表达人Api6(Apoptosis inhibitor 6)融合蛋白,为进一步研究Api6在凋亡抑制、脂质代谢和肿瘤发生中的作用奠定基础.方法:利用PCR技术扩增人Api6基因,将其克隆至原核表达载体ppSUMO,构建重组质粒ppSUMO-Api6;重组质粒转化原核表达宿主菌E.coli Rosetta感受态;采用蛋白原核表达的方法,不同诱导前菌液浓度,不同温度、不同异丙基硫化半乳糖苷(Isopropy 1-β-D-thiogalaotopyrano-side,IPTG)浓度、不同诱导时间,筛选诱导表达Api6重组蛋白的最优条件;Western blot鉴定其表达情况.结果:成功构建重组质粒ppSUMO-Api6;成功诱导Api6重组蛋白的原核表达,表达的最优条件为:OD600=0.5~0.8的重组菌,16℃、0.5 mmol/L IPTG诱导16 h.结论:含有人Api6 c

  18. Comparison of API 20E and invA PCR for identification of Salmonella enterica isolates from swine production units.

    Science.gov (United States)

    Nucera, Daniele M; Maddox, Carol W; Hoien-Dalen, Patricia; Weigel, Ronald M

    2006-09-01

    API 20E and invA PCR were evaluated for the identification of Salmonella enterica isolates from swine farms. API 20E had the highest agreement with other tests at the 99.9% likelihood level. Both tests had 100% sensitivity and 96% specificity compared to 16S rRNA sequencing. Compared to serotyping, both tests had 96% sensitivity; specificity was 86% for API 20E and 79% for invA PCR.

  19. Mutational epitope analysis and cross-reactivity of two isoforms of Api g 1, the major celery allergen.

    Science.gov (United States)

    Wangorsch, Andrea; Ballmer-Weber, Barbara K; Rösch, Paul; Holzhauser, Thomas; Vieths, Stefan

    2007-04-01

    For better understanding the cross-reactivity between the major birch pollen and celery allergens, Bet v 1 and Api g 1, respectively, putative epitope areas and structurally important positions for IgE-binding of the isoforms Api g 1.01 and Api g 1.02 were point mutated. The IgE binding capacities were measured in ELISA, the IgE cross-reactivity between the isoforms, mutants and Bet v 1 investigated by ELISA-inhibition experiments with serum pools from patients with confirmed celery allergy (DBPCFC). Api g 1.01 displayed a clearly higher frequency and capacity of IgE binding than Api g 1.02. In Api g 1.01, substitution of lysine against glutamic acid at amino acid position 44, a key residue of the Bet v 1 "P-loop", increased the IgE-binding properties. Structural instability due to proline insertion at position 111/112 resulted in loss of IgE binding of Api g 1.01, but not of Api g 1.02. Between Api g 1.01 and Api g 1.02 only partial cross-reactivity was seen. The data suggest that the IgE epitopes of the two isoforms are distinct and that in contrast to Api g 1.01, the "P-loop" region plays an important role for IgE binding of celery allergic subjects to Api g 1.02. Understanding and investigation of the molecular mechanisms in celery allergy is an important step to generate hypoallergenic proteins for safe and efficacious immunotherapy of food allergy.

  20. Software Defined GPS API: Development and Implementation of GPS Correlator Architectures Using MATLAB with Focus on SDR Implementations

    Science.gov (United States)

    2014-05-18

    NO. 0704-0188 3. DATES COVERED (From - To) - UU UU UU UU Approved for public release; distribution is unlimited. Software Defined GPS API : Development...and Implementation of GPS Correlator Architectures Using MATLAB with Focus on SDR Implementations The Software Defined GPS API was created with the...ABOVE ADDRESS. Polytechnic University of Puerto Rico 377 Ponce de Leon Ave. Hato Rey, PR 00918 -0000 ABSTRACT Software Defined GPS API : Development and