The neXtProt peptide uniqueness checker: a tool for the proteomics community.

Science.gov (United States)

Schaeffer, Mathieu; Gateau, Alain; Teixeira, Daniel; Michel, Pierre-André; Zahn-Zabal, Monique; Lane, Lydie

2017-11-01

The neXtProt peptide uniqueness checker allows scientists to define which peptides can be used to validate the existence of human proteins, i.e. map uniquely versus multiply to human protein sequences taking into account isobaric substitutions, alternative splicing and single amino acid variants. The pepx program is available at https://github.com/calipho-sib/pepx and can be launched from the command line or through a cgi web interface. Indexing requires a sequence file in FASTA format. The peptide uniqueness checker tool is freely available on the web at https://www.nextprot.org/tools/peptide-uniqueness-checker and from the neXtProt API at https://api.nextprot.org/. lydie.lane@sib.swiss. © The Author(s) 2017. Published by Oxford University Press.

Search of fission products in 20Ne-ion beam interaction with 165Ho at 8 MeV/nucleon

International Nuclear Information System (INIS)

Singh, D.; Ali, R.; Afzal Ansari, M.; Rashid, M.H.

2006-01-01

In the present work, during the study complete fusion (CF) and incomplete fusion (ICF) in 20 Ne-induced reactions, the production cross-sections for several fission products in 20 Ne + 165 Ho system have been measured

Interference of Coulomb and nuclear excitation in inelastic scattering of 20Ne from 40Ca

International Nuclear Information System (INIS)

Ratel, Guy.

1976-01-01

Angular distributions at 54 and 63MeV and excitation functions from 35 to 95MeV for the elastic and inelastic scattering of 20 Ne by 40 Ca have been measured. Experimental data for the inelastic scattering leading to the 20 Ne (2 + , 1.63MeV) state show a characteristic minimum for the angular distributions and excitation functions. This phenomenon was explained by an interference effect between Coulomb and nuclear excitation amplitudes with the DWBA and the coupled-channel formalism. The existence of this interference minimum could be explained only by assuming a nuclear deformation stronger than these obtained with light ion scattering. However a small shift between the experimental data and theoretical curves suggests that effects of a stronger complex coupling or nuclear reorientation due to the large quadrupole moment of 20 Ne must be included [fr

Main channels of the decay of the giant dipole resonance in the 20,22Ne nuclei and isospin splitting of the giant dipole resonance in the 22Ne nucleus

International Nuclear Information System (INIS)

Varlamov, V.V.; Stepanov, M.E.

2002-01-01

Data published in the literature on various photonuclear reactions for the 20,22 Ne isotopes and for their natural mixture are analyzed with the aim of exploring special features of the decay of giant-dipole-resonance states in these two isotopes. With the aid of data on the abundances of the isotopes and on the energy reaction thresholds, the cross sections for the reactions 20,22 Ne[(γ, n) + (γ, np)] and 20,22 Ne[(γ, p) + (γ, np)] are broken down into the contributions from the one-nucleon reactions (γ, n) and (γ, p) and the contributions from the reactions (γ, np). The cross sections evaporation model used here to treat the deexcitation of residual nucle(γ, p) 19,21 F in the energy range E γ = 16.0-28.0 MeV and the cross sections for the reactions 20,22 Ne(γ, np) 18,20 F in the energy range E γ = 23.3-28.0 MeV are estimated. The behavior of the cross-section ratio r = σ(γ, p)/σ(γ, n) for the 22 Ne nucleus as a function of energy is analyzed, and the isospin components of the giant dipole resonance in the 22 Ne nucleus are identified. The contributions of the isospin components of the giant dipole resonance in the 22 Ne nucleus to the cross sections for various photonuclear reactions are determined on the basis of an analysis of the diagram of the excitation and decay of pure isospin states in the 22 Ne nucleus and in nuclei neighboring it, which are members of the corresponding isospin multiplets. The isospin splitting of the giant dipole resonance and the ratio of the intensities of the isospin components are determined to be ΔE = 4.57 ± 0.69 MeV and R = 0.24 ± 0.04, respectively

Oceans 2.0 API: Programmatic access to Ocean Networks Canada's sensor data.

Science.gov (United States)

Heesemann, M.; Ross, R.; Hoeberechts, M.; Pirenne, B.; MacArthur, M.; Jeffries, M. A.; Morley, M. G.

2017-12-01

Ocean Networks Canada (ONC) is a not-for-profit society that operates and manages innovative cabled observatories on behalf of the University of Victoria. These observatories supply continuous power and Internet connectivity to various scientific instruments located in coastal, deep-ocean and Arctic environments. The data from the instruments are relayed to the University of Victoria where they are archived, quality-controlled and made freely available to researchers, educators, and the public. The Oceans 2.0 data management system currently contains over 500 terabytes of data collected over 11 years from thousands of sensors. In order to facilitate access to the data, particularly for large datasets and long-time series of high-resolution data, a project was started in 2016 create a comprehensive Application Programming Interface, the "Oceans 2.0 API," to provide programmatic access to all ONC data products. The development is part of a project entitled "A Research Platform for User-Defined Oceanographic Data Products," funded through CANARIE, a Canadian organization responsible for the design and delivery of digital infrastructure for research, education and innovation [1]. Providing quick and easy access to ONC Data Products from within custom software solutions, allows researchers, modelers and decision makers to focus on what is important: solving their problems, answering their questions and making informed decisions. In this paper, we discuss how to access ONC's vast archive of data programmatically, through the Oceans 2.0 API. In particular we discuss the following: Access to ONC Data Products Access to ONC sensor data in near real-time Programming language support Use Cases References [1] CANARIE. Internet: https://www.canarie.ca/; accessed March 6, 2017.

Mass distribution in 20Ne+232Th reaction

International Nuclear Information System (INIS)

Sodaye, Suparna; Tripathi, R.; Sudarshan, K.

2011-01-01

Mass distribution was measured in 20 Ne+ 232 Th reaction at E lab =145 MeV using recoil catcher technique followed by off-line gamma-ray spectrometry. Significant contribution from transfer fission was observed in the yield of comparatively neutron rich fission products. The variance of mass distribution for complete fusion fission, obtained by excluding neutron rich fission products, was observed to be consistent with the values reported in literature for similar reaction systems which showed a deviation from the systematics obtained using random neck rupture and liquid drop model. (author)

Efeito tóxico de alimentos alternativos para abelhas Apis mellifera Toxic effect of alternative feeds for honeybees Apis mellifera

Directory of Open Access Journals (Sweden)

Fábia de Mello Pereira

2007-04-01

Full Text Available Esta pesquisa foi realizada com o objetivo de avaliar a existência de efeito tóxico em alimentos protéicos alternativos fornecidos para abelhas Apis mellifera. Medindo-se o tempo médio de mortalidade e o índice de mortalidade de abelhas confinadas, avaliou-se a existência de efeito tóxico do: (a feno das folhas de mandioca (Manihot esculenta; (b feno das folhas de leucena (Leucaena leococephala; (c farinha de vagem de algaroba (Prosopis juliflora; (d farinha de vagem de bordão-de-velho (Pithecellobium cf. saman; (e farelo de babaçu (Orbygnia martiana e (f sucedâneo do leite para bezerros da marca Purina®. O tempo médio de mortalidade variou de 4,46 a 11,74 e o índice de mortalidade variou de 4,58 a 12,80. Durante o experimento, obsevou-se que as abelhas alimentadas com farinha de bordão-de-velho ficavam envoltas em uma crosta de alimento, morrendo asfixiadas posteriormente. Os resultados demonstraram que a farinha de bordão-de-velho não deve ser fornecida às abelhas. Não foi observado efeito tóxico nos demais alimentos estudados.The objective of this research was to study toxic effects of alternative feeds for honeybees Apis mellifera. The average mortality time and the mortality index of cagged honeybees were assessed to evaluate any possible toxic effect of: (a cassava hay (Manihot esculenta; (b leucaena hay (Leucaena leococephala; (c mesquite pod meal (Prosopis juliflora; (d "bordão-de-velho" pod meal (Pithecellobium cf. saman; (e babassu bran (Orbygnia martiana and (f succedaneous for calfskin from Purina®. The mortality time average varied from 4.46 to 11.74 and the mortality index varied between 4.58 and 12.80. It was obseved that honeybees fed with "bordão-de-velho" pod meal got involved by stichy layer of food and died asphyxiated. Results showed that the flour of Pithecellobium cf. saman should not be used for feeding honeybees, considering the early mortality of workers fed with this meal. The other food studied

Many-particle and many-hole states in neutron-rich Ne isotopes related to broken N=20 shell closure

International Nuclear Information System (INIS)

Kimura, Masaaki; Horiuchi, Hisashi

2004-01-01

The low-lying level structures of 26 Ne, 28 Ne and 30 Ne which are related to the breaking of the N=20 shell closure have been studied in the framework of the deformed-basis anti-symmetrized molecular dynamics plus generator coordinate method using the Gogny D1S force. The properties of the many-particle and many-hole states are studied as well as that of the ground band. We predict that the negative-parity states, in which neutrons are promoted into the pf-orbit from the sd orbit, have a small excitation energy in the cases of 28 Ne and 30 Ne. We regard this to be a typical phenomena accompanying the breaking of the N=20 shell closure. It is also found that the neutron 4p4h structure of 30 Ne appears at low excitation energy, which contains α + 16 O correlations. (author)

Influence of left right asymmetry degrees of freedom in self-consistent calculation of 20Ne

International Nuclear Information System (INIS)

Marcos, S.; Flocard, H.; Heenen, P.H.

1983-06-01

Within a constrained Hartree-Fock calculation we investigate the effects of left right asymmetric degrees of freedom associated with the channel 16 O + 4 He 20 Ne. We find a large softness of 20 Ne against octupole deformation. The optimal solution after restoration of the parity by means of a projection shows a pronouned 16 O + 4 He clustering. A generator coordinate calculation along the collective path confirms this conclusion. Once center of mass motion effects are taken into account a good agreement with experiment is found

Nuclear structure calculations in $^{20}$Ne with No-Core Configuration-Interaction model

OpenAIRE

Konieczka, Maciej; Satuła, Wojciech

2016-01-01

Negative parity states in $^{20}$Ne and Gamow-Teller strength distribution for the ground-state beta-decay of $^{20}$Na are calculated for the very first time using recently developed No-Core Configuration-Interaction model. The approach is based on multi-reference density functional theory involving isospin and angular-momentum projections. Advantages and shortcomings of the method are briefly discussed.

Systematic of fusion incompleteness in 20Ne induced reactions at energy 4-7 MeV/nucleon

International Nuclear Information System (INIS)

Ali, Sabir; Ahmad, Tauseef; Kumar, Kamal

2016-01-01

In the present work, a study of fusion incompleteness using the 20 Ne projectile over 51 V, 55 Mn and 59 Co and targets has been carried out. The experiment involving 20 N e+ 51 V system was performed at VECC, Kolkata, India. The targets of thickness range 1.19-1.50 rug/cm 2 of spectroscopically pure 51 V (purity 99.99%) were prepared by depositing on aluminum backing of thickness range 1.47-1.64 mg/cm 2 by the vacuum evaporation technique at the target lab of VECC. A stack of six 51 V targets was irradiated for ≈ 11 hrs by 20 Ne 6+ beam at ≈145 MeV. The irradiation of the stack covered the desired energy range of 82-145 MeV. The beam current was ≈ 40 nA during the irradiation hours. The energy of the 20 Ne ion beam incident on each target foil was calculated using stopping power software SRIM. The overall error in the present work is estimated to be ≤20%

Study of the 28Si(16O,20Ne)24Mg reaction

International Nuclear Information System (INIS)

Portezan Filho, O.

1988-01-01

In this work, measurements of elastic and inelastic angular distributions in the system 16 O+ 20 Si and in the alpha transfer reactions 20 Si( 16 O, 20 Ne) 24 Mg were made in the angular range of 20 0 0 and the transfer reaction 20 Si( 16 O, 12 C) 32 S in the angular range 16 0 0 at the energy of E cm = 31.57 MeV. Optical potential parameters and β 2 deformation parameters as well as spectroscopic factors were determined for the alpha transfer reactions. (A.C.A.S.) [pt

Toxicidade de produtos fitossanitários utilizados em citros para Apis mellifera Toxicity of pesticides used in citrus crop to Apis mellifera

Directory of Open Access Journals (Sweden)

Ana Paula Machado Baptista

2009-07-01

Full Text Available O objetivo deste trabalho foi avaliar a toxicidade de inseticidas/acaricidas utilizados em cultura de citros para operárias africanizadas de Apis mellifera Linnaeus. A exposição das abelhas aos compostos foi realizada usando-se técnicas de pulverização, contaminação da dieta e contato em superfícies tratadas (folhas de citros e placas de Petri, empregando-se as doses máximas recomendadas para a cultura. Os bioensaios foram realizados em laboratório a 25±2°C, UR 70±10% e fotofase de 12h, sendo os dados de mortalidade submetidos à análise estatística, e as médias comparadas por contraste, obtendo-se grupos de efeitos semelhantes. Independente do modo de exposição, o acefato foi extremamente tóxico, matando mais de 90,0% das abelhas 24h após a aplicação. Os produtos espirodiclofeno e piriproxifem, quando aplicados diretamente sobre as abelhas, causaram níveis de mortalidade de 11,0 e 15,0%, respectivamente; os compostos buprofezina, enxofre e tetradifona apresentaram níveis de mortalidade ainda menores, com média de 5,0% entre eles. Para os ensaios de contaminação de superfície (folhas de citros e placas de Petri e contaminação de alimento, foram obtidos dois grupos de toxicidade, um grupo somente com acefato e outro, com buprofezina, enxofre, espirodiclofeno, piriproxifem, tetradifona e água. A mortalidade média para esse segundo grupo, após 96h do início da exposição, foi de 31,0; 8,3 e 15,7%, respectivamente, para cada método de contaminação.The aim of this research was to evaluate the toxicity of several acaricides/insecticides used in Brazilian citrus crop to africanized workers of Apis mellifera Linnaeus. The exposition of honey bees to the chemicals was performed by direct spraying, contamination of food, and contact in treated surface (citrus leaves and Petri dishes, using recommended rates of application. The assays were carried out at 25±2°C, RH 70±10%, 12h of photophase and the data was

Study of an API migration for two XML APIs

NARCIS (Netherlands)

T.T. Bartholomei; K. Czarnecki; R. Lämmel (Ralf); T. van der Storm (Tijs); M.G.J. van den Brand (Mark); D. Gasevic; J. Gray

2010-01-01

htmlabstractAPI migration refers to adapting an application such that its dependence on a given API (the source API) is eliminated in favor of depending on an alternative API (the target API) with the source and target APIs serving the same domain. One may attempt to automate API migration by code

Constraining the 19Ne(p,γ)20Na Reaction Rate Using a Direct Measurement at DRAGON

Science.gov (United States)

Wilkinson, R.; Lotay, G.; Lennarz, A.; Ruiz, C.; Christian, G.; Akers, C.; Catford, W. N.; Chen, A. A.; Connolly, D.; Davids, B.; Hutcheon, D. A.; Jedrejcic, D.; Laird, A. M.; Martin, L.; McNeice, E.; Riley, J.; Williams, M.

2018-01-01

A direct measurement of the 19Ne(p, γ)20 Na reaction has been performed in inverse kinematics at the DRAGON recoil separator, at an energy ˜ 10 keV higher than previous measurements. The key resonance in the 19 Ne + p system relevant for ONe novae and Type-I X-ray burst temperatures have been successfully measured for the first time. Preliminary estimates of the resonance energy and strength are reported as Ec.m. ≈ 458 keV and ωγ ≈ 18 meV. These results are consistent with previous direct measurements, but disagree with the most recent study of the 19Ne(p, γ)20 Na reaction rate. These preliminary results will be finalised after a forthcoming negative log-likelihood analysis.

Separation of the 1+/1− parity doublet in 20Ne

Directory of Open Access Journals (Sweden)

J. Beller

2015-02-01

Full Text Available The (J,T=(1,1 parity doublet in 20Ne at 11.26 MeV is a good candidate to study parity violation in nuclei. However, its energy splitting is known with insufficient accuracy for quantitative estimates of parity violating effects. To improve on this unsatisfactory situation, nuclear resonance fluorescence experiments using linearly and circularly polarized γ-ray beams were used to determine the energy difference of the parity doublet ΔE=E(1−−E(1+=−3.2(±0.7stat(−1.2+0.6sys keV and the ratio of their integrated cross sections Is,0(+/Is,0(−=29(±3stat(−7+14sys. Shell-model calculations predict a parity-violating matrix element having a value in the range 0.46–0.83 eV for the parity doublet. The small energy difference of the parity doublet makes 20Ne an excellent candidate to study parity violation in nuclear excitations. Keywords: Parity doublet, Parity violation

Nuclear structure effects in fusion-fission of compound systems 20,21,22Ne formed in 10,11B+10,11B reactions

International Nuclear Information System (INIS)

Singh, BirBikram; Kaur, Manpreet; Kaur, Varinderjit; Gupta, Raj K.

2014-01-01

The dynamical cluster-decay model (DCM) of Gupta and collaborators has been successfully applied to the decay of number of hot and rotating compound nuclei in different mass regions, formed in low-energy heavy ion reactions. Recently, its application to the binary symmetric decay (BSD) of very light mass compound systems 20,21,22 Ne formed in 10,11 B+ 10,11 B reactions at E lab =48 MeV is extended, as the experimental data for σ BSD Expt . is available, namely, for 20 Ne (∼ 270 mb), 21 Ne ( 22 Ne ( BSD DCM for the BSD of the three Ne systems is calculated, comprising fusion-fission σ ff and deep inelastic scattering/orbiting σorb contributions (evaluated empirically here) from compound nucleus CN and non-compound nucleus nCN processes, respectively. The significant observation from this study is that, of the total σ BSD DCM , σ ff contribution is very strong for the decay of 20 Ne (=195.270 mb; >70%), followed by 21 Ne (=65.723 mb; ∼50%) and 22 Ne (=8.677 mb; almost 10%). This means that the process of collective clusterization within the DCM is playing very strong role for the decay of 20 Ne

libLocation: acceso a dispositivos de localización para gvSIG Desktop y Mobile

OpenAIRE

Jordán Aldasorro, Juan G.; Planells Jiménez, Manuel

2009-01-01

Inicialmente integrada en el piloto de gvSIG Mobile, la librería libLocation tiene como objetivo dotar a los proyectos gvSIG Desktop y gvSIG Mobile un acceso transparente a fuentes de localización. La librería se fundamenta en las especificaciones JSR-179 -API de localización para J2ME- y JSR-293 -API de localización para J2ME v2.0-, proporcionando una interfaz uniforme a diferentes fuentes de localización, mediante funciones de alto nivel. Asimismo, se extiende la funcionalida...

Comparison of biochemical and molecular methods for the identification of bacterial isolates associated with failed loggerhead sea turtle eggs.

Science.gov (United States)

Awong-Taylor, J; Craven, K S; Griffiths, L; Bass, C; Muscarella, M

2008-05-01

Comparison of biochemical vs molecular methods for identification of microbial populations associated with failed loggerhead turtle eggs. Two biochemical (API and Microgen) and one molecular methods (16s rRNA analysis) were compared in the areas of cost, identification, corroboration of data with other methods, ease of use, resources and software. The molecular method was costly and identified only 66% of the isolates tested compared with 74% for API. A 74% discrepancy in identifications occurred between API and 16s rRNA analysis. The two biochemical methods were comparable in cost, but Microgen was easier to use and yielded the lowest discrepancy among identifications (29%) when compared with both API 20 enteric (API 20E) and API 20 nonenteric (API 20NE) combined. A comparison of API 20E and API 20NE indicated an 83% discrepancy between the two methods. The Microgen identification system appears to be better suited than API or 16s rRNA analysis for identification of environmental isolates associated with failed loggerhead eggs. Most identification methods are not intended for use with environmental isolates. A comparison of identification systems would provide better options for identifying environmental bacteria for ecological studies.

Uma breve revisão histórica do desenvolvimento da soldagem dos aços API para tubulações A brief history review of development on API steels welding for pipeline

Directory of Open Access Journals (Sweden)

Jaime Casanova Soeiro Junior

2013-06-01

Full Text Available Este trabalho enfoca o desenvolvimento dos aços API para tubulações desde o aço API 5L X42, desenvolvido em 1948, através de laminação a quente seguida de tratamento térmico. Desde então foram feitos diferentes desenvolvimentos visando aumentar a resistência mecânica e a tenacidade, além de melhorar a soldabilidade. Entre eles, a adição de elementos de liga, produzindo os aços ARBL e a utilização de rotas de processamento termomecânico durante a laminação. Inicialmente a rota utilizada era a laminação a quente controlada (TMCR, com utilização de elemento microligante como Nb para os aços X60 e o conjunto Nb e V para os aços X65 e X70, associado a uma redução do teor de carbono. Posteriormente foi implantada a rota de fabricação do aço por laminação controlada seguida de resfriamento controlado (TMCP, com redução de carbono e adição de Nb e Ti para os aços X80, e adições de Mo, Nb, Be Ti para os X100. A redução do carbono foi motivada também para melhorar a sua soldabilidade e, por este motivo, estes aços são soldados por diferentes processos de soldagem, como o eletrodo revestido. Desenvolvimentos recentes com raiz feita com MAG-TC e enchimento com arame tubular tem dado resultados animadores.This paper is a brief history on the development of pipelines steels since the API 5L X42 steel, developed in 1948 by hot rolling followed by heat treatment. Subsequently different developments were made to increase the strength and toughness of these materials, and to improve their weldability. Among them, the addition of microalloying elements, producing HSLA steels and thermomechanical processing routes during hot rolling. Initially the route used was the controlled hot rolling (TMCR, together with microalloying element such as Nb for X60 steel and Nb plus V for X65 and X70 steels, associated with a reduction in carbon content. Later, the thermomechanical controlled process (TMCP manufacturing route was

APIs

CERN Document Server

Jacobson, Daniel; Woods, Dan

2011-01-01

Programmers used to be the only people excited about APIs, but now a growing number of companies see them as a hot new product channel. This concise guide describes the tremendous business potential of APIs, and demonstrates how you can use them to provide valuable services to clients, partners, or the public via the Internet. You'll learn all the steps necessary for building a cohesive API business strategy from experts in the trenches. Facebook and Twitter APIs continue to be extremely successful, and many other companies find that API demand greatly exceeds website traffic. This book offe

Experimental Investigation of the ^{19}Ne(p,γ)^{20}Na Reaction Rate and Implications for Breakout from the Hot CNO Cycle.

Science.gov (United States)

Belarge, J; Kuvin, S A; Baby, L T; Baker, J; Wiedenhöver, I; Höflich, P; Volya, A; Blackmon, J C; Deibel, C M; Gardiner, H E; Lai, J; Linhardt, L E; Macon, K T; Need, E; Rasco, B C; Quails, N; Colbert, K; Gay, D L; Keeley, N

2016-10-28

The ^{19}Ne(p,γ)^{20}Na reaction is the second step of a reaction chain which breaks out from the hot CNO cycle, following the ^{15}O(α,γ)^{19}Ne reaction at the onset of x-ray burst events. We investigate the spectrum of the lowest proton-unbound states in ^{20}Na in an effort to resolve contradictions in spin-parity assignments and extract reliable information about the thermal reaction rate. The proton-transfer reaction ^{19}Ne(d,n)^{20}Na is measured with a beam of the radioactive isotope ^{19}Ne at an energy around the Coulomb barrier and in inverse kinematics. We observe three proton resonances with the ^{19}Ne ground state, at 0.44, 0.66, and 0.82 MeV c.m. energies, which are assigned 3^{+}, 1^{+}, and (0^{+}), respectively. In addition, we identify two resonances with the first excited state in ^{19}Ne, one at 0.20 MeV and one, tentatively, at 0.54 MeV. These observations allow us for the first time to experimentally quantify the astrophysical reaction rate on an excited nuclear state. Our experiment shows an efficient path for thermal proton capture in ^{19}Ne(p,γ)^{20}Na, which proceeds through ground state and excited-state capture in almost equal parts and eliminates the possibility for this reaction to create a bottleneck in the breakout from the hot CNO cycle.

Measurement and analysis of excitation functions in 20Ne + 27Al system

International Nuclear Information System (INIS)

Pachouri, Dipti; Singh, D.; Ali, R.; Afzal Ansari, M.; Rashid, M.H.

2008-01-01

In the present work, the excitation functions (EFs) for radioactive residues produced in the interaction of 20 Ne ion with 27 Al have been measured in order to study the reaction dynamics, particularly in the low mass region using the off-line γ-ray measurement activation technique for bombarding energies below 150 MeV

Investigation of the parity forbidden alpha decay of 20Ne

International Nuclear Information System (INIS)

Disque, M.

1978-01-01

In this thesis the alpha decay of excited states in 20 Ne is investigated. The excited neon states are formed by proton bombardment of 19 F at proton energie of 340 and 670 kev. The ratio E of the parity forbidden alpha decays leading to the ground state of 160 to the allowed decays is determined. The results are E = 7.4 x 10 -5 resonance at 340 kev, E = 4.2 x 10 -3 resonance at 670 kev. (FKS)

The Dutch xAPI Experience: xAPI Recipes

OpenAIRE

Berg, Alan; Scheffel, Maren; Drachsler, Hendrik; Ternier, Stefaan; Specht, Marcus

2017-01-01

We present the collected experiences since 2012 of the Dutch Special Interest Group (SIG) for Learning Analytics in the application of the xAPI standard and best practices around the application of xAPI in various contexts. We present three projects that apply xAPI in very different ways and publish a consistent set of xAPI recipes.

Mass spectra and fusion cross sections for 20Ne+24Mg interaction at 55 and 85 MeV

International Nuclear Information System (INIS)

Grotowski, K.; Belery, P.; Delbar, T.; El Masri, Y.; Gregoire, G.; Janssens, R.; Vervier, J.; Paic, G.; Albinska, M.; Albinski, J.; Kopta, S.; Kozik, T.; Planeta, R.

1981-01-01

Inclusive γ spectra from the 20 Ne+ 24 Mg interaction have been measured using 55- and 85-MeV 20 Ne ions. The identification of γ lines allows the determination of mass spectra in the region 12< or =A< or =43. Experimental results are compared with statistical model calculations. The total reaction and fusion cross sections are extracted. Cross sections for inelastic scattering, few nucleon transfers, and deep inelastic scattering are estimated

Comparative virulence and competition between Nosema apis and Nosema ceranae in honey bees (Apis mellifera).

Science.gov (United States)

Milbrath, Meghan O; van Tran, Toan; Huang, Wei-Fong; Solter, Leellen F; Tarpy, David R; Lawrence, Frank; Huang, Zachary Y

2015-02-01

Honey bees (Apis mellifera) are infected by two species of microsporidia: Nosema apis and Nosemaceranae. Epidemiological evidence indicates that N. ceranae may be replacing N. apis globally in A. mellifera populations, suggesting a potential competitive advantage of N. ceranae. Mixed infections of the two species occur, and little is known about the interactions among the host and the two pathogens that have allowed N. ceranae to become dominant in most geographical areas. We demonstrated that mixed Nosema species infections negatively affected honey bee survival (median survival=15-17days) more than single species infections (median survival=21days and 20days for N. apis and N. ceranae, respectively), with median survival of control bees of 27days. We found similar rates of infection (percentage of bees with active infections after inoculation) for both species in mixed infections, with N. apis having a slightly higher rate (91% compared to 86% for N. ceranae). We observed slightly higher spore counts in bees infected with N. ceranae than in bees infected with N. apis in single microsporidia infections, especially at the midpoint of infection (day 10). Bees with mixed infections of both species had higher spore counts than bees with single infections, but spore counts in mixed infections were highly variable. We did not see a competitive advantage for N. ceranae in mixed infections; N. apis spore counts were either higher or counts were similar for both species and more N. apis spores were produced in 62% of bees inoculated with equal dosages of the two microsporidian species. N. ceranae does not, therefore, appear to have a strong within-host advantage for either infectivity or spore growth, suggesting that direct competition in these worker bee mid-guts is not responsible for its apparent replacement of N. apis. Copyright © 2014 Elsevier Inc. All rights reserved.

Efeitos de atrativos e repelentes sobre o comportamento da abelha (Apis mellifera, l. Effect of attractants and repellents on the behavior of honey bees (Apis mellipera, L.

Directory of Open Access Journals (Sweden)

D.T. MALERBO-SOUZA

1998-01-01

Full Text Available O objetivo do presente ensaio foi testar diversas substâncias e verificar sua atratividade e repelência para abelhas, Apis mellifera, L. Para isso, foram realizados testes em discos próximos às colméias e em cana picada oferecida como alimentação para gado bovino confinado. Nos discos próximos à colméia, o produto mais atrativo foi Bee-Here e o mais repelente foi o óleo de citronela. No cocho para bovinos, o repelente mais efetivo foi n-octyl-acetato.The experiment aimed to study honey bee (Apis mellifera attractants and repellents in vitro and on chopped sugar cane for bovine feeding. Tests were performed on plates located near to the hives and on bovine-hods. On plates, Bee-Here® was the most attractive and citronela oil the most repellent. On bovine-hods the most effective was n-octyl-acetate.

Determination of cross sections of nuclear reactions to use Al as monitoring foil in heavy ion irradiation with 20Ne projectile

International Nuclear Information System (INIS)

Chowdhury, D.P.; Datta, J.; Guin, R.; Verma, R.

2009-01-01

The beam current is generally accurately measured using monitoring foils during the irradiation of thick samples by high energy ion beams. The cross sections of many nuclear reactions induced by light particles are available in literature for use as monitoring foil. However, such cross sections of heavy ion induced reactions are not reported much for their use in applied works. We have determined cross sections of two nuclear reactions, 27 Al ( 20 Ne,2p2n) 43 Sc and 27 Al ( 20 Ne, 2pn) 44m Sc, to use Al as monitoring foil for the irradiation with 20 Ne heavy ion beam. (author)

Short range α-α repulsion and FR-DWIA analysis of the (α, 2α) reaction on 9Be and 20Ne

International Nuclear Information System (INIS)

Joshi, Bhushan N.; Jain, Arun K.

2009-01-01

The 9 Be and 20 Ne nuclei are supposed to be highly α-clustered because while 9 Be is a Borromean nucleus the 20 Ne nucleus is having 4-nucleons outside the closed shell 16 O nucleus. The same is also anticipated from the small α-separation energies for these two nuclei which are 2.4672 MeV and 4.7316 MeV respectively, in comparison the values for 16 O and 12 C nuclei are 7.1622 MeV, 7.367 MeV respectively. In order to verify the trend seen in 12 C and 16 O the theory should repeat itself in 9 Be and 20 Ne also

Investigation of incomplete fusion dynamics by measurement of excitation functions in the 20Ne + 59Co system

International Nuclear Information System (INIS)

Singh, D.; Linda, Sneha Bharti; Giri, Pankaj K.; Singh, Smita Shree; Kumar, Harish; Afzal Ansari, M.; Ali, Rahbar; Rashid, M.H.; Guin, R.; Das, S.K.

2015-01-01

In the present work, an attempt has been made to address some important aspects of CF and ICF dynamics for the system 20 Ne + 59 Co in the projectile energy range ≈ 62–150 MeV by using recoil catcher activation technique with the following off-line γ-ray spectroscopy. Excitation Functions (EFs) for the following reactions: 59 Co(Ne, α p4n) 70 Ga, 59 Co(Ne, 3αp3n) 63 Zn, 59 Co (Ne, 3αp4n) 62 Zn and 59 Co (Ne, 4α3n) 60 Cu have been measured. No precursor decay contribution has been observed for these measured evaporation residues. The measured values of total fusion cross-sections of the above evaporation residues have been compared with the theoretical total complete fusion cross sections calculated by code PACE-2, which do not take into account ICF contribution

Lääne-Virumaa TOP 100 aastal 2000

Index Scriptorium Estoniae

2001-01-01

Lääne-Virumaa edukamad ettevõtted; Lääne-Virumaa käibe TOP 100; Käibe kasvu TOP 20; Käibe languse TOP 10; Kasumi TOP 20; Kasumi kasvu TOP 20; Rentabluse TOP 20; ROA TOP 20; Kasumi languse TOP 10; Kahjumi TOP 10; Lääne-Virumaa käibelt suuremate ettevõtete finantsandmed. Lääne-Virumaa ettevõtete üldandmed

Elastic and inelastic form factors of the Ne20 in the Hartree-Fock approximation

International Nuclear Information System (INIS)

Oliveira, S.A.C. de.

1977-01-01

Properties of Ne 20 fundamental band are studied such as particle densities and elastic and inelastic form factors. A two body interaction is used and its matrix elements involve only the independent particle states of the 1s-0d shell [pt

Complete and incomplete fusion dynamics in 20Ne + 165Ho system

International Nuclear Information System (INIS)

Linda, Sneha Bharti; Giri, Pankaj K.; Singh, D.; Kumar, Harish; Afzal Ansari, M.; Ali, Rahbar; Rashid, M.H.; Guin, R.; Das, S.K.

2016-01-01

In the present work, an attempt has been made to address some of the important aspects of CF and ICF dynamics for the system 20 Ne + 165 Ho in the projectile energy range 4-8 MeV/nucleon by employing the recoil catcher technique followed by off-line γ-ray spectroscopy. The excitation functions (EFs) of the two ERs 171 Ta and 168 Hf have been measured. In the present measurement no precursor decay contributions has been measured

Charge and mass distribution in 20Ne induced fission of 181Ta

International Nuclear Information System (INIS)

Tripathi, R.; Sudarshan, K.; Goswami, A.; Reddy, A.V.R.; Guin, R.

2005-01-01

Charge and mass distribution studies have been carried out at E lab =180 MeV in 20 Ne induced fission of 181 Ta. The mass distribution has been found to be symmetric. The width of the mass distribution has been theoretically calculated using the random neck rupture of Brosa et al. A good agreement between the calculated and experimental mass distribution has been observed. (author)

Plan PrEFiNE: Plan estratégico para la enfermedad de Fabry en Nefrología

Directory of Open Access Journals (Sweden)

M.D. del Pino

2016-07-01

Discusión: El plan PrEFiNE nos permitirá evaluar la utilidad de un proyecto dirigido a mejorar el conocimiento de una enfermedad minoritaria como la EF a nivel nacional, y a partir del cual se podrán establecer las recomendaciones necesarias para mejorar su reconocimiento, además de planes enfocados a mejorar las necesidades no cubiertas detectadas durante su desarrollo.

/sup 16/O(/sup 16/O, /sup 12/C)/sup 20/Ne reaction in the framework of the coupled channel formalism

Energy Technology Data Exchange (ETDEWEB)

Krause, O; Scheid, W; Greiner, W [Frankfurt Univ. (Germany, F.R.). Inst. fuer Theoretische Physik

1974-01-01

The transfer reaction /sup 16/O(/sup 16/O, /sup 12/C)/sup 20/Ne is treated in the coupled channel formalism. The influence of the transfer channels on the intermediate structure in the elastic excitation function is discussed. The /sup 16/O and /sup 20/Ne-nuclei are described in an ..cap alpha..-cluster model.

Recenzija. Monografija apie filosofijos ir literatūros giminystę

Directory of Open Access Journals (Sweden)

Tomas Kačerauskas

2011-04-01

Full Text Available Prieš keletą metų neoficialiame pokalbyje J. Baranova prasitarė, kad nėra didesnio malonumo už rašymą. Tiesą sakant, buvau sužavėtas ir priblokštas ne tik dėl šios ištaros asimetrijos R. Barthes’o minčiai apie skaitymo malonumą (net erotinį. Visai kitaip apie rašymą atsiliepia A. Šliogeris (kurio filosofi jos apmąstymui J. Baranova pelnytai skiria daug dėmesio: jis mieliau nerašytų nei rašytų. Tokiais atvejais prisimenu M. Bulgakovą, kuris „tempiąs save už plaukų prie rašomojo stalo“. Rašymas daug kam siejasi su disciplina, prievarta savęs atžvilgiu, geriausiu atveju – kasdieniu įpročiu.

Feasibility of same-day identification of members of the family Vibrionaceae by the API 20E system.

OpenAIRE

Overman, T L; Overley, J K

1986-01-01

Sixty isolates, comprising nine species of the family Vibrionaceae, were tested with the API 20E 5-h same-day procedure (Analytab Products, Plainview, N.Y.). Included were 27 Aeromonas hydrophila isolates, 10 Aeromonas sobria isolates, 7 Aeromonas caviae isolates, 3 Plesiomonas shigelloides isolates, 3 Vibrio alginolyticus isolates, 3 Vibrio cholerae isolates, 1 Vibrio fluvialis isolate, 5 Vibrio parahaemolyticus isolates, and 1 Vibrio vulnificus isolate. The 5-h profile numbers were specific...

A review of 20 Ne structure in a full microscopic self-consistent shell ...

African Journals Online (AJOL)

A set of single-particle energies together with a set of two-body matrix- elements derived in a self –consistent manner from the Reid soft–core potential are used to calculate the energy levels of 20Ne. We used a harmonic oscillator wave function folded with two-body correlation functions in our calculation. It is found that the ...

Potential energy surfaces for N = Z, 20Ne-112Ba nuclei

International Nuclear Information System (INIS)

Mehta, M.S.; Gupta, Raj K.; Jha, T.K.; Patra, S.K.

2004-01-01

We have calculated the potential energy surfaces for N = Z, 20 Ne- 112 Ba nuclei in an axially deformed relativistic mean field approach. A quadratic constraint scheme is applied to determine the complete energy surface for a wide range of the quadrupole deformation. The NL3, NL-RAl and TM1 parameter sets are used. The phenomenon of (multiple) shape coexistence is studied and the calculated ground and excited state binding energies, quadrupole deformation parameters and root mean square (rms) charge radii are compared with the available experimental data and other theoretical predictions. (author)

Population Genetics of Nosema apis and Nosema ceranae: One Host (Apis mellifera) and Two Different Histories

Science.gov (United States)

Maside, Xulio; Gómez-Moracho, Tamara; Jara, Laura; Martín-Hernández, Raquel; De la Rúa, Pilar; Higes, Mariano; Bartolomé, Carolina

2015-01-01

Two microsporidians are known to infect honey bees: Nosema apis and Nosema ceranae. Whereas population genetics data for the latter have been released in the last few years, such information is still missing for N. apis. Here we analyze the patterns of nucleotide polymorphism at three single-copy loci (PTP2, PTP3 and RPB1) in a collection of Apis mellifera isolates from all over the world, naturally infected either with N. apis (N = 22) or N. ceranae (N = 23), to provide new insights into the genetic diversity, demography and evolution of N. apis, as well as to compare them with evidence from N. ceranae. Neutral variation in N. apis and N. ceranae is of the order of 1%. This amount of diversity suggests that there is no substantial differentiation between the genetic content of the two nuclei present in these parasites, and evidence for genetic recombination provides a putative mechanism for the flow of genetic information between chromosomes. The analysis of the frequency spectrum of neutral variants reveals a significant surplus of low frequency variants, particularly in N. ceranae, and suggests that the populations of the two pathogens are not in mutation-drift equilibrium and that they have experienced a population expansion. Most of the variation in both species occurs within honey bee colonies (between 62%-90% of the total genetic variance), although in N. apis there is evidence for differentiation between parasites isolated from distinct A. mellifera lineages (20%-34% of the total variance), specifically between those collected from lineages A and C (or M). This scenario is consistent with a long-term host-parasite relationship and contrasts with the lack of differentiation observed among host-lineages in N. ceranae (mellifera worldwide population is a recent event. PMID:26720131

Experimental study of radiative pion capture on 13C, 20Ne, 90Zr, 19F and 12C

International Nuclear Information System (INIS)

Martoff, C.J.

1980-11-01

Photon spectra for 50 13 C, 19 F, 20 Ne, and 90 Zr. The e + e - pair spectrometer system used has resolution 850 keV fwhm and photon detection efficiency 5 x 10 -6 . The total radiative capture branching ratios measured are 13 C (1.66 +- 0.25)%, 19 F (2.40 +- 0.48)%, 20 Ne (1.60 +- 0.24)%, and 90 Zr (2.1 +- 0.5)%. The partial radiative capture branching ratios to four bound states and two resonances in 20 F, and two bound states and three resonances in 13 B have also been measured. The branching ratio for 13 C(π - ,γ) 13 B g.s. is (6.1 +- 1.2) x 10 -4 . Comparison of this result with the beta decay rate of 13 B shows that (84 +- 16)% of the pion capture amplitude is accounted for by the Gamow-Teller matrix element. Further analysis suggests that much of the remaining strength is E2. The measured branching ratios to resonant states in 13 C(π - ,γ) 13 B are shown to be in agreement with detailed shell model calculations. The total single-particle strength in these transitions is shown to be approximately half as large as that of the T = 3/2 part of the E1 photoresonance (the Giant Dipole Resonance) in 13 C. The branching ratio for 20 Ne(π - ,γ) 20 F (T = 1, J/sup π/ = 1 + , E/sub x/ = 1.06 MeV) is 0.91 +- 0.52).10 -4 . Comparison with the electroexcitation of the analog giant M1 state in 20 Ne (11.24 MeV) shows that the M1 transition amplitude is less than (46 +- 14)% Gamow-Teller. This result is in agreement with detailed shell model calculations of the M1 transition. The photon spectrum for radiative pion capture from flight (reaction 12 C(π + T = 44 MeV, γ at 90 0 )) has been measured. 13 figures, 12 tables

β-delayed γ decay of 20Mg and the 19Ne(p , γ) 20 Na breakout reaction in Type I X-ray bursts

Science.gov (United States)

Glassman, B. E.; Pérez-Loureiro, D.; Wrede, C.; Allen, J.; Bardayan, D. W.; Bennett, M. B.; Brown, B. A.; Chipps, K. A.; Febbraro, M.; Friedman, M.; Fry, C.; Hall, M. R.; Hall, O.; Liddick, S. N.; O'Malley, P.; Ong, W. J.; Pain, S. D.; Prokop, C.; Schwartz, S. B.; Shidling, P.; Sims, H.; Thompson, P.; Zhang, H.

2018-03-01

Certain astrophysical environments such as thermonuclear outbursts on accreting neutron stars (Type-I X-ray bursts) are hot enough to allow for breakout from the Hot CNO hydrogen burning cycles to the rapid proton capture (rp) process. An important breakout reaction sequence is 15O(α,γ)19Ne(p,γ)20Na and the 19Ne(p,γ)20Na reaction rate is expected to be dominated by a single resonance at 457 keV above the proton threshold in 20Na. The resonance strength and, hence, reaction rate depends strongly on whether this 20Na state at an excitation energy of 2647 keV has spin and parity of 1+ or 3+. Previous 20Mg (Jπ =0+) β+ decay experiments have relied almost entirely on searches for β-delayed proton emission from this resonance in 20Na to limit the log ft value and, hence, Jπ. However there is a non-negligible γ-ray branch expected that must also be limited experimentally to determine the log ft value and constrain Jπ. We have measured the β-delayed γ decay of 20Mg to complement previous β-delayed proton decay work and provide the first complete limit based on all energetically allowed decay channels through the 2647 keV state. Our limit confirms that a 1+ assignment for this state is highly unlikely.

{beta}-Delayed proton-decay study of {sup 20}Mg and its implications for the {sup 19}Ne(p,{gamma}){sup 20}Na breakout reaction in X-ray bursts

Energy Technology Data Exchange (ETDEWEB)

Wallace, J.P., E-mail: J.P.Wallace@sms.ed.ac.uk [University of Edinburgh, Edinburgh, EH9 3JZ (United Kingdom); Woods, P.J.; Lotay, G. [University of Edinburgh, Edinburgh, EH9 3JZ (United Kingdom); Alharbi, A.; Banu, A. [Cyclotron Institute, Texas A and M University, College Station, TX (United States); David, H.M.; Davinson, T. [University of Edinburgh, Edinburgh, EH9 3JZ (United Kingdom); McCleskey, M.; Roeder, B.T.; Simmons, E.; Spiridon, A.; Trache, L.; Tribble, R.E. [Cyclotron Institute, Texas A and M University, College Station, TX (United States)

2012-05-30

Under astrophysical conditions of high temperature and density, such as for example found in X-ray bursts, breakout can occur from the hot CNO cycles into the rapid proton capture process. A key breakout route is via the sequence {sup 15}O({alpha},{gamma}){sup 19}Ne(p,{gamma}){sup 20}Na. The {sup 19}Ne(p,{gamma}){sup 20}Na reaction rate is expected to be dominated by a single resonance at 457(3) keV. The identity of the resonance has been under discussion for a long time, with J{sup {pi}}=1{sup +} and 3{sup +} assignments suggested. In this study of the {beta}-delayed proton decay of {sup 20}Mg we report a new, significantly more stringent, upper limit on the {beta}-decay branch to this state of 0.02% with a confidence level of 90%. This makes a 1{sup +} assignment highly unlikely and favours a 3{sup +} assignment for which no branch is expected to be observed. The 3{sup +} state is predicted to have a significantly higher resonance strength, and to produce a proportionately higher {sup 19}Ne(p,{gamma}){sup 20}Na reaction rate in X-ray burst conditions.

The systematics of the (18O,20Ne) reaction and its application to the determination of the mass excess of 122Cd

International Nuclear Information System (INIS)

Kruechten, B. van.

1987-01-01

The aim of the thesis should be the determination of the mass excess of the neutron-deficient nucleus 122 Cd with the ( 18 O, 20 Ne) reaction proved for light target nuclei (A lab ≤ 15 0 ) lay below the detection limit of 1 μb/sr it was first necessary to determine optimum kinematical conditions for the study of the reaction 124 Sn( 18 O, 20 Ne). For this purpose systematic studies of the angular distributions of the ( 18 O, 20 Ne) reaction on target nuclei with mass numbers between 28 ( 28 Si) and 208 ( 208 Pb) were performed at beam energies of 82, 102, 141, and 189 MeV. The evaluation of these measurements gave first information on the dependences of the cross sections on energy, Q-value, target mass, and angle. For the 124 Sn( 18 O, 20 Ne) 122 Cd reaction a maximum cross section of about 1 μb/sr at a beam energy 30 MeV above the Coulomb threshold (100 MeV) and a laboratory angle of 40 0 could be expected. In a new experiment this prediction could be verified. The analysis of the measured spectra yielded a Q-value for the 124 Sn( 18 O, 20 Ne) 122 Cd reaction of 0.1 ± 0.44 MeV. The mass excess of -82.08 ± 0.44 MeV calculated from this for 122 Cd is by 1.5 MeV more positive than the prediction of the Wapstra table. (orig./HSI) [de

Drug Interaction API

Data.gov (United States)

U.S. Department of Health & Human Services — The Interaction API is a web service for accessing drug-drug interactions. No license is needed to use the Interaction API. Currently, the API uses DrugBank for its...

Lääne-Virumaa ettevõtete TOP aastal 2004

Index Scriptorium Estoniae

2005-01-01

Tabelid: Lääne-Virumaa ettevõtete TOP 50; Käibe TOP 35; Kasumi TOP 35; Lääne-Virumaa ettevõtete üld- ja finantsandmed; Käibe kasvu TOP 20; Kasumi kasvu TOP 20; Rentaabluse TOP 20; Omakapitali tootlikkuse TOP 20. Vt. samas: Viktor Sepp, Merike Lees. Lääne-Virumaal üllatavad uued tegijad

BEHAVIOUR CORROSION OF API 5L X70 AND API 5L X80 STEELS IN A CO2 MEDIUM BY SURFACE ANALYSIS AND ELECTROCHEMICAL TECHNIQUES

OpenAIRE

MILAGROS MABEL GUILLEN NUNEZ

2006-01-01

A seleção de materiais para o transporte de óleo e gás não é feita pela sua resistência à corrosão, mas sim pelas suas boas propriedades mecânicas, facilidade de fabricação e baixos custos. Devido às taxas de perda de material, causado pela corrosão interna, existe necessidade em se conhecer o comportamento dos aços de mais alta resistência, utilizados especialmente em gasodutos e oleodutos tais como API 5L X70 e API 5L X80. Um dos elementos responsáveis ...

Resolution and sensitivity of the eyes of the Asian honeybees Apis florea, Apis cerana and Apis dorsata.

Science.gov (United States)

Somanathan, Hema; Warrant, Eric J; Borges, Renee M; Wallén, Rita; Kelber, Almut

2009-08-01

Bees of the genus Apis are important foragers of nectar and pollen resources. Although the European honeybee, Apis mellifera, has been well studied with respect to its sensory abilities, learning behaviour and role as pollinators, much less is known about the other Apis species. We studied the anatomical spatial resolution and absolute sensitivity of the eyes of three sympatric species of Asian honeybees, Apis cerana, Apis florea and Apis dorsata and compared them with the eyes of A. mellifera. Of these four species, the giant honeybee A. dorsata (which forages during moonlit nights) has the lowest spatial resolution and the most sensitive eyes, followed by A. mellifera, A. cerana and the dwarf honeybee, A. florea (which has the smallest acceptance angles and the least sensitive eyes). Moreover, unlike the strictly diurnal A. cerana and A. florea, A. dorsata possess large ocelli, a feature that it shares with all dim-light bees. However, the eyes of the facultatively nocturnal A. dorsata are much less sensitive than those of known obligately nocturnal bees such as Megalopta genalis in Panama and Xylocopa tranquebarica in India. The differences in sensitivity between the eyes of A. dorsata and other strictly diurnal Apis species cannot alone explain why the former is able to fly, orient and forage at half-moon light levels. We assume that additional neuronal adaptations, as has been proposed for A. mellifera, M. genalis and X. tranquebarica, might exist in A. dorsata.

Excitation of giant resonances in 20Ne + 90Zr and 208Pb inelastic scattering at 40 MeV/u1

International Nuclear Information System (INIS)

Suomijaervi, T.; Beaumel, D.; Blumenfeld, Y.; Chomaz, P.; Frascaria, N.; Garron, J.P.; Jacmart, J.C.; Roynette, J.C.; Kraus, L.; Link, I.

1988-01-01

The giant resonance region in the inelastic spectra from the reactions 20 Ne + 90 Zr and 20 Ne + 208 Pb at 40 MeV/nucleon has been studied with a good energy and angular resolutions. The strength distributions of the different multipolarities contributing to the cross section were obtained by a resonance shape independent analysis. In the case of 208 Pb the GDR strength was found to be strongly shifted towards lower excitation energies which can be explained by the exponentially decreasing Coulomb excitation probability. Furthermore, indications for a high multipolarity component in the resonance structure were found in both reactions

Elastic scattering of polarized protons by 20Ne between 4.5 Mev and 5.5 Mev

International Nuclear Information System (INIS)

Avila A, O.L.

1979-01-01

Starting with the study of 20 Ne(p,p) 20 nuclear reaction, we obtained information about the nuclear structure of 21 Na. The experiment was made at Notre Dame University; a target of 20 Ne was bombarded with polarized protons, changing the incident energy of them between 4.5 Mev and 5.5 Mev at intervals of 10 keV. Fourteen detectors were set covering angles from 35 degrees until 165 degrees, with intervals of 10 degrees each. In this form measurements for computing polarization and differential sections were obtained, with them an analysis of runnings of phase was made, and the parameters associated with two of the excited levels of the composed formed nucleous 21 Na, that are viewed as resonances in the section were settled; those resonances correspond to a level Psub(3/2) of energy excitation 6.877, a total width of 36 keV, and a level Fsub(7/2) of energy excitation 6.992 and total width of 48 keV. I hope that these results will be part of a set of values that will be utilized in order to confront them with the existent nuclear models. (author)

DIRAC RESTful API

International Nuclear Information System (INIS)

Casajus Ramo, A; Graciani Diaz, R; Tsaregorodtsev, A

2012-01-01

The DIRAC framework for distributed computing has been designed as a flexible and modular solution that can be adapted to the requirements of any community. Users interact with DIRAC via command line, using the web portal or accessing resources via the DIRAC python API. The current DIRAC API requires users to use a python version valid for DIRAC. Some communities have developed their own software solutions for handling their specific workload, and would like to use DIRAC as their back-end to access distributed computing resources easily. Many of these solutions are not coded in python or depend on a specific python version. To solve this gap DIRAC provides a new language agnostic API that any software solution can use. This new API has been designed following the RESTful principles. Any language with libraries to issue standard HTTP queries may use it. GSI proxies can still be used to authenticate against the API services. However GSI proxies are not a widely adopted standard. The new DIRAC API also allows clients to use OAuth for delegating the user credentials to a third party solution. These delegated credentials allow the third party software to query to DIRAC on behalf of the users. This new API will further expand the possibilities communities have to integrate DIRAC into their distributed computing models.

Análise físico-química dos méis das abelhas Apis mellifera e Melipona scutellaris produzidos em regiões distintas no Estado da Paraíba

OpenAIRE

Evangelista-Rodrigues,Adriana; Silva,Eva Mônica.Sarmento da; Beserra,Ennio Marcello Fernandes; Rodrigues,Marcelo Luis

2005-01-01

O mel de abelhas é um produto muito apreciado, no entanto, de fácil adulteração com açúcares ou xaropes. Desta forma, é necessário que haja algumas análises para a determinação da sua qualidade para que seja comercializado. Este trabalho teve como objetivo fazer a análise físico-química dos méis de abelha Apis mellifera. e Melipona scutellaris para a comparação entre as espécies e entre as localidades do Brejo e do Cariri (regiões do Estado da Paraíba). Observou-se que o mel de abelha nativa ...

Windows API funkcijų sekų perėmimo bibliotekų tyrimas Windows API Hooking Libraries Research

Directory of Open Access Journals (Sweden)

Lukas Radvilavičius

2011-08-01

Full Text Available

Nagrinėjamos bibliotekos, skirtos Windows API funkcijų sekų perėmimui. Sekų perėmimas gali būti panaudojamas įvairiose srityse: siekiant išsiaiškinti operacinės sistemos veikimo principus, norint atlikti programos derinimą arba pridėti papildomą funkcionalumą prie jau esamo. Straipsnyje apžvelgiamos Windows API ir pateikiamos trečiųjų šalių priemonės funkcijų sekoms  perimti. Aptariamos jų teikiamos galimybės, panaudojimo specifika. Taip pat atlikti testai, siekiant išsiaiškinti, kuri biblioteka su užduotimis susitvarko greičiausiai. Tyrimui pasirinkti du nemokami gaminiai: Microsoft Detours ir EasyHook bibliotekos.

Straipsnis lietuvių kalba

20">The paper describes methods how to apply Windows API hooking with third party libraries and solutions. In this research were used Windows API function SetWindowsHookEx, Detours and EasyHook libraries. Libraries methods, features and advantages were discussed in this paper. The practical part contains libraries tests. In analysis we tested target program start with hooking library and injected function call.

Article in Lithuanian

Complete fusion 20Ne + 12C at 110 MeV

International Nuclear Information System (INIS)

Saulnier, J.-C.

1978-01-01

Identification in mass and charge of products of the reaction 20 Ne (Elab = 110 MeV) + 12 C has been obtained using a time-of-flight system and a ΔE-E telescope. Angular distributions and energy spectra have been measured between laboratory angles of 3,7 0 and 17 0 . The fusion cross-section has been measured to be 1270 +- 150 mb, with the reaction cross-section of 1700 +- 170 mb. Yields of evaporation residues are compared to predictions of the code GROGI2, using the Hauser-Feshbach angular momentum dependent formalism. Calculations of the laboratory energy and angular distributions of evaporation residues are carried out and compared with the experimental data for several center of mass angular distributions (isotropic, 1/sin theta, 1/sin 2 theta) [fr

Android quick APIs reference

CERN Document Server

Cinar, Onur

2015-01-01

The Android Quick APIs Reference is a condensed code and APIs reference for the new Google Android 5.0 SDK. It presents the essential Android APIs in a well-organized format that can be used as a handy reference. You won't find any technical jargon, bloated samples, drawn out history lessons, or witty stories in this book. What you will find is a software development kit and APIs reference that is concise, to the point and highly accessible. The book is packed with useful information and is a must-have for any mobile or Android app developer or programmer. In the Android Quick APIs Refe

Fractional momentum transfer in incomplete fusion reaction: measurement of recoil range distributions in 20Ne + 159Tb system

International Nuclear Information System (INIS)

Ali, R.; Singh, D.; Pachouri, Dipti; Afzal Ansari, M.; Rashid, M.H.

2007-01-01

The recoil range distribution (RRD) of several residues have been measured for the system 20 Ne + 159 Tb at 165 MeV beam energy by collecting the recoiling residues in the Al-catcher foils of varying thickness

Uranium target fragmentation by intermediate and high energy 12C and 20Ne ions

International Nuclear Information System (INIS)

McGaughey, P.L.; Loveland, W.; Morrissey, D.J.; Aleklett, K.; Seaborg, G.T.

1985-01-01

Target fragment formation cross sections for nuclides with 24 12 C and 8.0 and 20.0 GeV 20 Ne with 238 U. Fragment isobaric yields were deduced from these data. The light fragment (A 12 C projectile energy of 1.0 GeV, the n-deficient fragments appear to originate primarily from a fission rather than a spallation process.) The excitation functions of the heavy fragments with 60 60, indicating that the general pattern of yields of these fragments is governed by the excitation energy deposited in the nucleus during the first step of the reaction and the geometry of the collision

Photo-double ionisation of the Ne 2s studied in equal-energy-sharing condition at 20 eV above threshold

Energy Technology Data Exchange (ETDEWEB)

Bolognesi, P. [CNR-IMIP, Area della Ricerca di Roma 1, CP10, 00016 Monterotondo Scalo (Italy); Otranto, S. [CONICET and Depto. de Fisica, Universidad Nacional del Sur, 8000 Bahia Blanca (Argentina); Garibotti, C.R. [CONICET and Centro Atomico Bariloche, 8400 S.C. de Bariloche (Argentina); Flammini, R. [CNR-IMIP, Area della Ricerca di Roma 1, CP10, 00016 Monterotondo Scalo (Italy); Alberti, G. [CNR-IMIP, Area della Ricerca di Roma 1, CP10, 00016 Monterotondo Scalo (Italy); Avaldi, L. [CNR-IMIP, Area della Ricerca di Roma 1, CP10, 00016 Monterotondo Scalo (Italy)]. E-mail: lorenzo.avaldi@imip.cnr.it

2005-06-15

The triple differential cross-section (TDCS) for the photo-double ionisation of Ne leading to the Ne{sup 2+}(2s{sup -2}2p{sup 6}) has been measured 20 eV above threshold in equal-energy-sharing conditions. The results are compared with the recently introduced SC3 model, which can be used to study targets different from He since it allows an easy implementation with different initial-state wavefunctions.

Development of an API 5 L X 70 coil for the production of API pipes continuously welded by electric resistance; Desenvolvimento de bobina API 5 L X 70 para producao de tubos API soldados continuamente por resistencia eletrica

Energy Technology Data Exchange (ETDEWEB)

Lopes, Alexandre R; Cavalheiro, Benedito C [CONFAB Tubos S.A., Sao Caetano do Sul, SP (Brazil)

1998-07-01

The manufacturing of high strength ERW pipe, which applies the continuous forming process, is known to lead to a relevant economy in a productivity basis. The past few years shown a trend of changing on grade range, from the past X52 to the present X70. The manufacturing of the latter grades for coils are somehow difficult due to the high Bauschinger effect observed on ERW pipes with ferritic-perlitic microstructure, that results in pipes with yield strength much lower than in coils, as on limitations on rolling, where controlled rolling is not applied. In this work, acicular dispersed bainite was searched, in a way to reduce this effect after pipe forming. API 5L X70 coils, from USIMINAS, were processed including an intentional addition of Molybdenum in the range of 0.20%, together with Columbium and Vanadium (added as 0.050% average). (author)

Mass resolved angular distribution of fission products in 20Ne + 232Th reaction

International Nuclear Information System (INIS)

Tripathi, R.; Sodaye, S.; Sudarshan, K.; Kumar, Amit; Guin, R.

2011-01-01

Mass resolved angular distribution of fission products was measured in 20 Ne + 232 Th reaction at beam energy of 120 MeV. A preliminary analysis of the angular distribution data of fission products shows higher average anisotropy compared to that calculated using statistical theory. A signature of rise in anisotropy near symmetry, as reported in earlier studies in literature, is also seen. Further study is in progress to get more detailed information about the contribution from non-compound nucleus fission and dependence of angular anisotropy on asymmetry of mass division

Inhibition of the growth of Ascosphaera apis by Bacillus and Paenibacillus strains isolated from honey Inhibición del crecimiento de Ascosphaera apis mediante cepas de Bacillus y Paenibacillus aisladas de miel

Directory of Open Access Journals (Sweden)

F. J. Reynaldi

2004-03-01

Full Text Available The fungus Ascosphaera apis, the causative agent of chalkbrood disease in honeybee larvae, occurs throughout the world and is found in many beekeeping areas of Argentina. The potential as biocontrol agents of 249 aerobic spore-forming bacterial antagonists isolated from honey samples was evaluated. Each isolate was screened against A. apis by a central disk test assay. Ten bacterial strains that showed the best antagonistic effect to A. apis were selected for further study and identified as Bacillus cereus (m363, mv86, mv81, mv75, Bacillus circulans (Fr231, m448b, Bacillus megaterium (m435, Bacillus pumilus (m354, Bacillus subtilis (m329, and Paenibacillus alvei (m321. For testing the efficiency of the selected strains, a paired culture test was used with 5 replicates of each combination bacterial antagonist / A. apis strain, and 5 replications for each control on 4 different culture media. The analysis of variance and posterior comparison of means according to LSD method showed that the best antagonists when using YGPSA medium were B. subtilis (m329 and B. megaterium (m435, and in the case of MYPGP medium the most efficient were B. circulans strains Fr 231 and m448b.La cría yesificada es una micosis invasiva ocasionada por el hongo heterotálico Ascosphaera apis que afecta exclusivamente a las larvas de las abejas. La enfermedad tiene difusión mundial y en la Argentina se halla diseminada en todas las áreas donde se realiza apicultura. Se estudió la potencialidad de 249 cepas de bacterias esporuladas aeróbicas aisladas de miel como agentes biocontroladores del hongo mediante un ensayo en disco central en condiciones de laboratorio. Se seleccionaron como mejores antagonistas 10 cepas bacterianas identificadas como Bacillus cereus (m363, mv86, mv81, mv75, Bacillus circulans (Fr231, m448b, Bacillus megaterium (m435, Bacillus pumilus (m354, Bacillus subtilis (m329, y Paenibacillus alvei (m321. Para probar la eficiencia de las cepas

Evaluación de un procedimiento de soldadura para el AISI 4130 sin PWHT bajo normas API 6A y ASME Sección IX

OpenAIRE

Naranjo, Carlos; Sánchez, Xavier; Morales, Juan

2014-01-01

Resumen— Debido a la complejidad de realizar postcalentamiento en campo necesario para garantizar las propiedades mecánicas de una junta soldada de acero AISI 4130 de acuerdo con las normas API 6A [1] y ASME Sección IX[2], y evitar la presencia de martensita en la estructura metalográfica de la junta, siendo esta última perjudicial en los aceros y provocada por enfriamientos rápidos. Se ve la necesidad de desarrollar un procedimiento de soldadura capaz de satisfacer mencionadas condiciones si...

Deformation and orientation effects in the binary symmetric decay of 20,21,22Ne*

International Nuclear Information System (INIS)

Singh, BirBikram; Kaur, Manpreet; Gupta, Raj K.

2014-01-01

We have extended the study of binary symmetric decay (BSD) of extremely light mass compound systems 20,21,22 Ne* formed in 10,11 B+ 10,11 B reactions at E lab = 48 MeV, to explore the role of deformations and orientations, using the Dynamical Cluster decay Model (DCM). In the present work, we find that with inclusion of quadruple deformations and 'hot compact' orientations of nuclei σ ff increases in comparison to the case of spherical considerations of nuclei

Web API Fragility : How Robust is Your Web API Client

NARCIS (Netherlands)

Espinha, T.; Zaidman, A.; Gross, H.G.

2014-01-01

Web APIs provide a systematic and extensible approach for application-to-application interaction. A large number of mobile applications makes use of web APIs to integrate services into apps. Each Web API’s evolution pace is determined by their respective developer and mobile application developers

Healthcare Finder API

Data.gov (United States)

U.S. Department of Health & Human Services — All of the data used on the Finder.HealthCare.gov web application is available through this API. There are multiple collections of data available through the API. 1....

Depth profiling of {sup 14} N and {sup 20} Ne implantation into iron and steel using(p, gamma) reactions. Vol. 2

Energy Technology Data Exchange (ETDEWEB)

Wriekat, A; Haj-Abdellah, M [Physics Department, University of Jordan, Amman (Jordan)

1996-03-01

Depth profiles of {sup 14} N and {sup 20} Ne ions at 800 KeV implanted into iron and by steel samples have been measured by means of the proton induced {gamma}- ray emission (Pige) technique. The range, R, and range straggling, {Delta}R for these profiles were obtained and compared with theoretical calculations. The experimental results did show that pure iron retains more N and Ne than steel. 2 figs., 1 tab.

Clarification of some api characteristics in relation to caribou (Rangifer tarandus

Directory of Open Access Journals (Sweden)

William O. Pruitt, Jr.

1990-09-01

Full Text Available A total of 2177 comparisons of api hardness vs. density in northern Saskatchewan, southeastern Manitoba and northeastern Finland revealed no consistent correlation (r varied from +.70 to -.17. A total of 1395 comparisons of horizontal hardness of the top layer of api to vertical hardness of the same layer of api in southeastern Manitoba, northeastern Finland and far eastern middle Finland revealed no consistent correlation (r varied from +.99 to -.20. Therefore one cannot substitute density for hardness nor horizontal hardness of the top layer for vertical hardness of the top layer in the terms of the Värriö Snow Index.

Violence of heavy-ion reactions from neutron multiplicity: 11 to 20A MeV /sup 20/Ne+ /sup 238/U

International Nuclear Information System (INIS)

Jahnke, U.; Ingold, G.; Hilscher, D.; Lehmann, M.; Schwinn, E.; Zank, P.

1986-01-01

The suitability of the neutron multiplicity as a gauge for the violence of medium-energy heavy-ion reactions is investigated for the first time. For this purpose the number of neutrons emitted from fission reactions induced by 220-, 290-, and 400-MeV /sup 20/Ne on /sup 238/U is registered event-by-event with a large 4π scintillator tank. It is shown that the neutron multiplicity is indeed closely related to the two quantities characterizing the violence: the induced total intrinsic excitation and the linear momentum transfer

Electron capture on 20Ne and the ultimate fate of stars in the mass range 8-10 M⊙

International Nuclear Information System (INIS)

Kirsebom, Oliver S.; Cederkall, Joakim; Jenkins, David G.; Joshi, Pankaj; Julin, Rauno; Kankainen, Anu; Trzaska, Wladyslaw H.; Kibedi, Tibor; Tengblad, Olof

2016-01-01

Knowledge of the electron-capture rate on 20 Ne is of critical importance to understand the final evolution of stars in the mass range 8-10M⊙. A recent study has highlighted the importance of the second-forbidden transition between the ground states of 20 Ne and 20 F, which is believed to dominate the capture rate in an important temperature-density range. The strength of this transition is, however, not well constrained, neither experimentally nor theoretically, making an experimental determination highly desirable. The transition strength can be determined from the branching ratio of the inverse transition in the decay of 20 F, for which the experimental upper limit is 10 -5 , while the most recent theoretical prediction is 1.3 x 10 -6 . To facilitate an experimental determination of the branching ratio we are refurbishing an intermediate-image magnetic spectrometer capable of focusing 7 MeV electrons, and designing a scintillator detector surrounded by an active cosmic-ray veto shield, which will serve as an energy- dispersive device at the focal plane. In this contribution, GEANT4 simulations of the expected performance of the setup will be presented and the astrophysical motivation for the experiment will be discussed. (author)

Transcriptome differences in the hypopharyngeal gland between Western Honeybees (Apis mellifera) and Eastern Honeybees (Apis cerana).

Science.gov (United States)

Liu, Hao; Wang, Zi-Long; Tian, Liu-Qing; Qin, Qiu-Hong; Wu, Xiao-Bo; Yan, Wei-Yu; Zeng, Zhi-Jiang

2014-08-30

Apis mellifera and Apis cerana are two sibling species of Apidae. Apis cerana is adept at collecting sporadic nectar in mountain and forest region and exhibits stiffer hardiness and acarid resistance as a result of natural selection, whereas Apis mellifera has the advantage of producing royal jelly. To identify differentially expressed genes (DEGs) that affect the development of hypopharyngeal gland (HG) and/or the secretion of royal jelly between these two honeybee species, we performed a digital gene expression (DGE) analysis of the HGs of these two species at three developmental stages (newly emerged worker, nurse and forager). Twelve DGE-tag libraries were constructed and sequenced using the total RNA extracted from the HGs of newly emerged workers, nurses, and foragers of Apis mellifera and Apis cerana. Finally, a total of 1482 genes in Apis mellifera and 1313 in Apis cerana were found to exhibit an expression difference among the three developmental stages. A total of 1417 DEGs were identified between these two species. Of these, 623, 1072, and 462 genes showed an expression difference at the newly emerged worker, nurse, and forager stages, respectively. The nurse stage exhibited the highest number of DEGs between these two species and most of these were found to be up-regulated in Apis mellifera. These results suggest that the higher yield of royal jelly in Apis mellifera may be due to the higher expression level of these DEGs. In this study, we investigated the DEGs between the HGs of two sibling honeybee species (Apis mellifera and Apis cerana). Our results indicated that the gene expression difference was associated with the difference in the royal jelly yield between these two species. These results provide an important clue for clarifying the mechanisms underlying hypopharyngeal gland development and the production of royal jelly.

Impact of Nosema ceranae and Nosema apis on individual worker bees of the two host species (Apis cerana and Apis mellifera) and regulation of host immune response.

Science.gov (United States)

Sinpoo, Chainarong; Paxton, Robert J; Disayathanoowat, Terd; Krongdang, Sasiprapa; Chantawannakul, Panuwan

Nosema apis and Nosema ceranae are obligate intracellular microsporidian parasites infecting midgut epithelial cells of host adult honey bees, originally Apis mellifera and Apis cerana respectively. Each microsporidia cross-infects the other host and both microsporidia nowadays have a worldwide distribution. In this study, cross-infection experiments using both N. apis and N. ceranae in both A. mellifera and A. cerana were carried out to compare pathogen proliferation and impact on hosts, including host immune response. Infection by N. ceranae led to higher spore loads than by N. apis in both host species, and there was greater proliferation of microsporidia in A. mellifera compared to A. cerana. Both N. apis and N. ceranae were pathogenic in both host Apis species. N. ceranae induced subtly, though not significantly, higher mortality than N. apis in both host species, yet survival of A. cerana was no different to that of A. mellifera in response to N. apis or N. ceranae. Infections of both host species with N. apis and N. ceranae caused significant up-regulation of AMP genes and cellular mediated immune genes but did not greatly alter apoptosis-related gene expression. In this study, A. cerana enlisted a higher immune response and displayed lower loads of N. apis and N. ceranae spores than A. mellifera, suggesting it may be better able to defend itself against microsporidia infection. We caution against over-interpretation of our results, though, because differences between host and parasite species in survival were insignificant and because size differences between microsporidia species and between host Apis species may alternatively explain the differential proliferation of N. ceranae in A. mellifera. Copyright © 2017 Elsevier Ltd. All rights reserved.

Dynamical fission life-times deduced from gamma-ray emission observed in the fusion-fission reaction : Ne-20 on Bi-209.

NARCIS (Netherlands)

vanderPloeg, H; Bacelar, JCS; Buda, A; Dioszegi, [No Value; vantHof, G; vanderWoude, A

1996-01-01

The gamma-ray emission spectra between 4 and 20 MeV have been measured for the fusion-fission reactions Ne-20 on Bi-209 --> Np-229* at beam energies 150, 186 and 220 MeV. In addition for the latter experiment the angular dependence of the gamma-ray emission with respect to the spin axis has been

Pathogen detection and gut bacteria identification in Apis cerana ...

African Journals Online (AJOL)

A total of 50 colonies of Apis cerana were sampled in Samut Songkhram (five colonies) and Chumphon (45 colonies) provinces in the central and the south of Thailand, respectively. Diagnostic multiplex polymerase chain reaction (PCR) revealed that 20, 6, 4, 20 and 0% of the samples were infected by Paenibacillus larvae, ...

A comparison of Api 20A vs MALDI-TOF MS for routine identification of clinically significant anaerobic bacterial strains to the species level.

Science.gov (United States)

Kierzkowska, Marta; Majewska, Anna; Kuthan, Robert T; Sawicka-Grzelak, Anna; Młynarczyk, Grażyna

2013-02-15

Adequate identification of anaerobic bacteria still presents a challenge for laboratories conducting microbiological diagnostics. The aim of this study was to compare the use of Api 20A and MALDI-TOF MS techniques for identification of obligate anaerobes. The results indicate that MALDI-TOF MS ensures a rapid and accurate identification of the species isolated from patients. Copyright © 2012 Elsevier B.V. All rights reserved.

Yoink: An interaction-based partitioning API.

Science.gov (United States)

Zheng, Min; Waller, Mark P

2018-05-15

Herein, we describe the implementation details of our interaction-based partitioning API (application programming interface) called Yoink for QM/MM modeling and fragment-based quantum chemistry studies. Interactions are detected by computing density descriptors such as reduced density gradient, density overlap regions indicator, and single exponential decay detector. Only molecules having an interaction with a user-definable QM core are added to the QM region of a hybrid QM/MM calculation. Moreover, a set of molecule pairs having density-based interactions within a molecular system can be computed in Yoink, and an interaction graph can then be constructed. Standard graph clustering methods can then be applied to construct fragments for further quantum chemical calculations. The Yoink API is licensed under Apache 2.0 and can be accessed via yoink.wallerlab.org. © 2018 Wiley Periodicals, Inc. © 2018 Wiley Periodicals, Inc.

The putative serine protease inhibitor Api m 6 from Apis mellifera venom: recombinant and structural evaluation.

Science.gov (United States)

Michel, Y; McIntyre, M; Ginglinger, H; Ollert, M; Cifuentes, L; Blank, S; Spillner, E

2012-01-01

Immunoglobulin (Ig) E-mediated reactions to honeybee venom can cause severe anaphylaxis, sometimes with fatal consequences. Detailed knowledge of the allergic potential of all venom components is necessary to ensure proper diagnosis and treatment of allergy and to gain a better understanding of the allergological mechanisms of insect venoms. Our objective was to undertake an immunochemical and structural evaluation of the putative low-molecular-weight serine protease inhibitor Api m 6, a component of honeybee venom. We recombinantly produced Api m 6 as a soluble protein in Escherichia coli and in Spodoptera frugiperda (Sf9) insect cells.We also assessed specific IgE reactivity of venom-sensitized patients with 2 prokaryotically produced Api m 6 variants using enzyme-linked immunosorbent assay. Moreover, we built a structural model ofApi m 6 and compared it with other protease inhibitor structures to gain insights into the function of Api m 6. In a population of 31 honeybee venom-allergic patients, 26% showed specific IgE reactivity with prokaryotically produced Api m 6, showing it to be a minor but relevant allergen. Molecular modeling of Api m 6 revealed a typical fold of canonical protease inhibitors, supporting the putative function of this venom allergen. Although Api m 6 has a highly variant surface charge, its epitope distribution appears to be similar to that of related proteins. Api m 6 is a honeybee venom component with IgE-sensitizing potential in a fraction of venom-allergic patients. Recombinant Api m 6 can help elucidate individual component-resolved reactivity profiles and increase our understanding of immune responses to low-molecular-weight allergens

Absconding and migratory behaviors of feral Africanized honey bee (Apis mellifera L. colonies in NE Brazil = Comportamentos de abandono e migração de colônias silvestres da abelha melífera africanizada (Apis mellifera L. no nordeste do Brasil

Directory of Open Access Journals (Sweden)

Breno Magalhães Freitas

2007-10-01

Full Text Available We investigated the annual movements of feral Africanized honey bee (Apis mellifera L. colonies in the state of Ceará, Brazil, aiming to understand seasonal variations in their population. Arrival and absconding of Africanized honey bee (AHB colonies in the semiaridmunicipality of Canindé and the coastal humid city of Fortaleza (120 km apart were recorded weekly from January 1999 to December 2001, and the data compared to rainfall records in both areas. Results showed that AHB colonies only nest in the semiarid during the rainy season and abscond during the dry season, the opposite from observations taken in Fortaleza. Only 5% of colonies remained in the semiarid area for the entire year due to ant (Camponotus sp. attacks and shortage of nectar and water during the dry season, with most colonies migrating to coastal areas where the weather is milder and many plant species bloom at that time of year. Excessive rainfallprobably pushes AHB colonies back to the semiarid during the rainy season. We concluded that absconding and migration are strategies that allow AHB colonies to survive in the semiarid NE of Brazil, contrary to European honeybees, which have never succeeded in establishing wild colonies in the region.Os movimentos de colônias silvestres da abelha melífera africanizada (Apis mellifera L. no Estado do Ceará, Brasil, foram investigados com o objetivo de compreender variações anuais em sua população. A chegada e a partida de colônias de abelhas africanizadas (AHB,no município semi-árido de Canindé e na úmida cidade litorânea de Fortaleza (separadas por 120 km, foram monitoradas semanalmente, de janeiro de 1999 a dezembro de 2001, e comparados com os dados pluviométricos de chuvas em ambas as áreas. Os resultadosdemonstraram que as abelhas africanizadas somente nidificaram no semi-árido durante a estação chuvosa e o abandonaram na estação seca, ao contrário do observado em Fortaleza. Apenas 5% das col

Data.gov CKAN API

Data.gov (United States)

General Services Administration — The data.gov catalog is powered by CKAN, a powerful open source data platform that includes a robust API. Please be aware that data.gov and the data.gov CKAN API...

Excitation of the giant quadrupole resonance in /sup 58/Ni with /sup 20/Ne

CERN Document Server

Bohlen, H G; Ingold, G; Lettau, H; Ossenbrink, H; von Oertzen, W

1981-01-01

The heavy-ion induced excitation of the quadrupole resonance in /sup 58/Ni has been studied with /sup 20/Ne beams of 14.5 and 19.6 MeV/N incident energy. The broad resonance structure is clearly observed; the strength exhausts 44% and 60% of the energy weighted sum rule (EWSR) at the two incident energies, respectively. The background is partly explained by a three-body reaction mechanism, which is based on the one-nucleon pick-up reaction into unbound states followed by one- nucleon emission. The remaining part is interpreted as inelastic excitation of other multipoles. (11 refs).

Ação tóxica de Manihot glaziovii Muell. Arg. sobre Apis mellifera L.

Directory of Open Access Journals (Sweden)

Francivaldo Marcio Pereira

2014-06-01

Full Text Available As Apis mellifera, são polinizadores de diversas espécies de vegetais, contribuindo com eficiência na reprodução de várias culturas de interesse econômico, sendo a florada necessária para sua sobrevivência, porem certas plantas podem conter substâncias tóxicas para esses indivíduos. Nesse sentido o objetivo foi avaliar o possível efeito tóxico de flores de Manihot glaziowii para abelhas Apis mellifera. O experimento foi conduzido no Laboratório de Abelhas e Nutrição Animal da Universidade Federal de Campina Grande em Pombal-PB. As flores de M. glaziovii foram coletadas no sitio Bom Jesus localizado no Município de Pombal-PB transportadas para o laboratório e postas para secar em estufa a 40 °C durante 48 horas, trituradas e peneiradas, pesado em três concentrações distintas (0,25%, 0,50% e 1,0% com relação ao peso do cândi. O macerado das flores foi misturado ao cândi e colocadas em recipientes de plásticos de 10 ml.  As abelhas foram selecionadas no favo de cria, recém-emergidas, pelo tamanho e coloração mais clara, e conduzidas para o laboratório.  Distribuídas em conjunto de 20 insetos em caixa de madeira, medindo 11 cm de comprimento X 11 de largura e 7 cm de altura e orifícios nas laterais. Em cada caixa foram colocados dois recipientes de plástico de 10 mL com a dieta contaminada e um chumaço de algodão embebido com água. Acondicionadas em câmara tipo B.O.D. com temperatura a 32º C e umidade relativa de 70 %. O experimento foi realizado no delineamento inteiramente casualisado, composto por três tratamentos (0,25%, 0,50% e 1,0% e uma testemunha, com três repetições. A contagem de operárias mortas ocorreu vinte e quatro horas após aplicação dos tratamentos. Os dados foram passados para o programa PRISMA 3.0, para análises dos dados utilizou-se o teste não-paramétrico Log Rank Test, na comparação das curvas de sobrevivência. O macerado das flores de M. glaziovii apresentaram toxicidade

Produtos naturais no comportamento defensivo de Apis mellifera L. = Natural products in the defensive behaviour of Apis mellifera L.

Directory of Open Access Journals (Sweden)

Renata Leonardo Lomele

2010-07-01

Full Text Available Os objetivos do estudo foram investigar a influência de produtos naturais como capim-limão (Cymbopogon citratus, folhas de abacateiro (Persea americana, casca de café (Coffea arabica e sementes de mamona (Ricinus communis na defensividade de Apis mellifera, e avaliar o efeito destes produtos no desenvolvimento populacional da colmeia. O comportamento defensivo foi avaliado por meio do tempo da primeira ferroada (TPF, número de ferrões (NFB e, o desenvolvimento populacional, pela área de cria aberta e fechada. Observou-se que o tratamento fumaça + sete sementes de mamona apresentou aumento significativo no TPF, em relação ao tratamento sem e com fumaça de maravalha. Com relação ao NFB, verificou-se que os tratamentos fumaça de maravalha + sete sementes de mamona e fumaça de maravalha + 20% de folhas de café foram diferentes do tratamento sem e com fumaça. Os demais tratamentos não diferiram significativamente em relação ao uso da fumaça ou sua ausência. A casca de café e a semente de mamona nãointerferiram no desenvolvimento populacional, sugerindo que estes compostos não foram tóxicos. Pode-se concluir que o uso de sementes de mamona e casca de café na fumaça pode representar importante ferramenta para a redução da defensividade, sem promover toxicidade para A. mellifera.The goal was to investigate the influence of natural products such as lemongrass (Cymbopogon citratus, dried avocado leaves (Persea americana, coffee husk (Coffea arabica and castor bean (Ricinus communis in the defense of Apis mellifera, as well the effect of these products on the population development of the beehive. Defensive behavior was evaluated by time of first sting (TFS and number of stingers (NS, and population development, by open brood area and operculated brood. It was observed that the treatment with smoke + seven castor beans presented significant increase in the TFS, for treatment without and with smoke. Regarding NS, it was verified

Precise determination of cosmogenic Ne in CREU-1 quartz standard, using the Helix-MC Plus mass spectrometer

Science.gov (United States)

Hamilton, D.; Honda, M.; Zhang, X.; Phillips, D.; Matchan, E.

2017-12-01

The Helix-MC Plus multi-collector noble gas mass spectrometer at the Australian National University is uniquely equipped with three high mass resolution collectors on H2, Axial and L2 positions. Their mass resolution and mass resolving power are as high as 1,800 and 8,000, respectively. The Helix-MC Plus can totally separate 20Ne+ from 40Ar++ isobaric interference and also partially separate 21Ne+ from 20NeH+ and 22Ne+ from 12C16O2++. By adjusting collector positions, we are able to measure interference-free Ne isotope intensities and have re-determined the 21Ne abundance in air [1]. Analyses by Honda et al. [1] demonstrated that 20Ne1H contributes approximately 2% to previously determined atmospheric 21Ne values [2], and a new atmospheric 21Ne/20Ne ratio of 0.002906 was calculated. Using the Helix-MC Plus mass spectrometer, we measured Ne abundances in the CREU-1 quartz standard [3] and determined cosmogenic concentrations by subtraction of atmospheric Ne with the new atmospheric 21Ne/20Ne value. The average concentration of cosmogenic 21Ne determined from four repeated analyses is 338 ± 12 × 106 atom/g (2σ). This compares with the average concentration of 348 ± 10 × 106 atom/g (2σ) from 45 analyses determined by several laboratories [3], where Ne isotope analyses were undertaken by conventional low resolution mass spectrometers and atmospheric Ne was subtracted using the conventional atmospheric 21Ne/20Ne [2]. On this basis, for a sample with abundant cosmogenic Ne, like CREU-1 quartz, previously measured by low mass resolution mass spectrometers are likely valid and their geological implications are unaffected. However, for low 21Ne concentration samples, combining new generation of mass spectrometers as well as the new atmospheric ratio may have significance for cosmogenic 21Ne surface exposure dating. References: [1] Honda M., et. al., International Journal of Mass Spectrometry, 387, 1 (2015). [2] Eberhardt P., et. al., Zeitschrift fur Naturforschung, 20

Selección bidireccional de Apis mellifera (Hymenoptera: Apidae para aumento de la resistencia y la susceptibilidad a la nosemosis

Directory of Open Access Journals (Sweden)

Yamandú MENDOZA

2014-01-01

Full Text Available La nosemosis es una enfermedad que afecta las funciones digestivas de las abejas melíferas causada por los microsporidios Nosema apis y Nosema ceranae. En Uruguay la única especie detectada es N. ceranae. Para determinar si la incidencia de N. ceranae en las colonias tiene un componente genético se realizó una selección bidireccional para aumento de la resistencia y la susceptibilidad a este parásito sin control de la paternidad. Las colonias fueron evaluadas en una forestación de Eucalyptus grandis en otoño. La infección de las colonias se determinó como 1 el porcentaje de abejas pecoreadoras infectadas y 2 el número promedio de esporas por campo en 10 campos. El trabajo se inició con 138 colonias y se evaluaron dos generaciones de 30 y 63 colonias. La respuesta a la selección fue muy limitada, solo en la primera generación las colonias de la línea resistente presentaron menos esporas por abejas que las colonias de la línea susceptible (19,6 ± 5,8 y 26,8 ± 10,4, respectivamente, W = 41,5; P = 0.03. Esto indicaría que la resistencia a la nosemosis está fuertemente afectada por el ambiente. Futuros esfuerzos para aumentar la resistencia de las abejas a N. ceranae a través de mejora genética deberán incluir el control de la paternidad.

CraftCosta: Creación de un plug-in MMORPG para servidores de Minecraft

OpenAIRE

VALLDECABRES BARRERA, JULIÁN

2016-01-01

[ES] Desarrollo de un complemento para Minecraft que transforme un servidor convencional de Minecraft, en un servidor MMORPG, extendiendo y haciendo uso de la API de Minecraft (Bukkit) y aportando una interfaz gráfica para el administrador del juego. [EN] Development of a plugin to transform a conventional Minecraft server into a MMORPG server, extending and using the Minecraft API (Bukkit) and providing a graphical interface for the game administrator. Valldecabres Barrera,...

Fission-like decay of 20Ne: eccentric behavior in the B+B fusion processes

International Nuclear Information System (INIS)

Toledo, A.S. de; Coimbra, M.M.; Added, N.; Anjos, R.M.; Carlin Filho, N.; Fante Junior, L.; Figueira, M.C.S.; Guimaraes, V.; Szanto, E.M.

1988-08-01

Cross sections for the fusion of 10,11 B+ 10,11 B have been measured in the energy range from 1.5 MeV/A to 5 MeV/A. The 10 B+ 10 B system unexpectedly presents a hindered fusion cross section when compared to the 10 B+ 11 B and 11 B+ 11 B reactions and to standard model predictions. The missing fusion cross section was diverted the 10 B exit channel with a total kinetic energy characteristic of strongly damped collisions. Q-values and kinematical analysis together with angular distributions suggest a binary symmetric decay of the composite 20 Ne system. (author) [pt

Analyses of electron and proton scattering to low excitation isoscalar states in 20Ne, 24Mg and 28Si

International Nuclear Information System (INIS)

Amos, K.; Bauhoff, W.

1983-01-01

Intermediate energy inelastic proton scattering differential cross section and polarization data from the 2 1 + states in 24 Mg and 28 Si and from the 4 1 + states in 28 Si have been analysed using the Distorted Wave Approximation with large basis models of nuclear structure. These structure models were tested by use in analyses of the longitudinal form factors obtained from inelastic electron scattering, so that analyses of the intermediate energy (p,p') data from the same transitions are then sensitive tests of the two-nucleon t-matrix. Data from these and other 2 1 + transitions in 12 C and 20 Ne at 49 MeV (24 MeV in the case of 20 Ne), were also analysed to compare models of t-matrices at lower energies. An ancilliary study of the momentum transfer dependence of effective charges has been made as both s-d shell and large basis structure models have been used to compare with form factor data up to momentum transfers of 2.5 fm -1 . The deduced momentum dependence of the effective charges is significant

O tempo vivido na perspectiva fenomenológica de Eugène Minkowski El tiempo vivido en la perspectiva fenomenológica de Eugène Minkowski The lived-time in the phenomenological perspective of Eugène Minkowski

Directory of Open Access Journals (Sweden)

Virginia E. Suassuna Martins Costa

2009-06-01

Full Text Available Este artigo tem como objetivo abordar as concepções de tempo assimilado ao espaço e de tempo vivido, especificando seus elementos estruturais e os fenômenos a eles relacionados, com base na perspectiva de Eugène Minkowski. Para tal, evidencia algumas conceituações a respeito do tempo em Santo Agostinho e em Henry Bergson", assim com em alguns aspectos biográficos de Minkowski, que contribuíram para a compreensão a respeito do fenômeno tempo. Como meta, pretende oferecer subsídios para a reflexão dos profissionais de saúde no encontro clínico.Este artículo tiene el objetivo de tratar sobre los conceptos del tiempo asimilados al espacio y del tiempo vivido, especificando sus elementos estructurales y fenómenos relacionados, embasados en la perspectiva de Eugène Minkowski. Para esto, se evidencia algunos conceptos relacionados con el tiempo en Santo Agostinho y en Henry Bergson, así como los aspectos biográficos de Minkowski que han contribuido para entenderse sobre el fenómeno del tiempo. Como meta, este artículo se propone a ofrecer subsidios a la reflexión por los profesionales de salud en el encuentro clínico.This article has the objective to deal about the conceptions of time assimilated with the space and the lived time, specifying its structural elements and related phenomena, based on Eugène Minkowski's perspective. For this, it is evidenced some concepts related to time in Saint Augustin and in Henry Bergson, as well as some Minkowski's biographic aspects that have contributed for understanding about time's phenomenon. As a goal, this paper intends to offer subsidies for the reflection by health professionals on clinic meeting.

HEURISTIC EVALUATION FOR MOBILE APPLICATION (STUDI KASUS: APLIKASI DEPO AUTO 2000 TANJUNG API API PALEMBANG

Directory of Open Access Journals (Sweden)

Usman Ependi

2017-11-01

Full Text Available Heuristic evaluation merupakan salah satu bentuk usability testing perangkat lunak yang dinilai oleh pengguna (evaluator. Dalam melakukan heuristic evaluation instrumen penilaian terdiri dari sepuluh (10 pernyataan dengan lima pilihan jawaban dalam skala severity ratings. Dalam penelitian ini heuristic evaluation terhadap aplikasi Depo Auto 2000 Tanjung Api-Api Palembang yang dilakukan oleh 4 evaluator.  Hasil dari heuristic evaluation dikelompokkan kedalam  masing-masing instrumen yaitu visibility of system status dengan nilai 0,75, match between system and the real world dengan nilai 0,25, user control and freedom dengan nilai 0,25, consistency and standards dengan nilai 0,75, error prevention dengan nilai 1, recognition rather than recall dengan nilai 1,25, flexibility and efficiency of use dengan nilai 0,25, Aesthetic and minimalist design dengan nilai 0,25, help users recognize, diagnose, and recover from errors dengan nilai 1 dan Help and documentation dengan nilai 0. Dari hasil heuristic evaluation yang dilakukan menunjukkan bahwa evaluator memberikan nilai 0 dan 1 aplikasi Depo Atuo 2000 Tanjung Api-Api Palembang. Hasil penilaian tersebut menunjukkan bahwa aplikasi yang buat tidak ada masalah usability dan hanya memiliki cosmetic problem sehingga aplikasi Depo Auto 2000 Tanjung Api Api Palembang  dapat dinyatakan layak untuk didistribusikan kepada pengguna akhir (end user.

Eficacia del Oxavar® para el Control del Ácaro Varroa destructor (Varroidae en Colmenas de Apis mellifera (Apidae Efficacy of Oxavar® to control the mite Varroa destructor (Varroidae in honeybee colonies of Apis mellifera (Apidae

Directory of Open Access Journals (Sweden)

Jorge Augusto Marcangeli

2003-12-01

Full Text Available El objetivo del trabajo fue evaluar la eficacia del producto Oxavar® para el control del ácaro Varroa destructor (Anderson & Trueman en colmenas de abejas Apis mellifera durante la primavera de 2002 y otoño de 2003. El trabajo se llevó a cabo en el apiario experimental del Centro de Extensión Apícola ubicado en Coronel Vidal, provincia de Buenos Aires. Se trabajó sobre un total de 20 colmenas tipo Langstroth que se dividieron en dos grupos iguales. El primer grupo recibió 5 ml de Oxavar® (323 g en 5000 ml de agua destilada por cuadro cubierto por abejas. El segundo grupo, el testigo, recibió 5 ml de agua destilada por cuadro cubierto por abejas. Ambos grupos recibieron tres dosis a intervalos de siete días. Semanalmente, se recolectaron los ácaros muertos caídos en pisos especiales que evitaban que las abejas los eliminen. Posteriormente, en los dos grupos se colocaron tiras del producto Apistan® para eliminar los ácaros remanentes en las colonias y poder así calcular la eficacia del tratamiento. El producto Oxavar® presentó una eficacia promedio de 85,5 % ± 2,8 durante la primavera y 86,1% ± 2,6 durante el otoño, no mostrando diferencias significativas entre las estaciones (p> 0,05. En ambos casos se registraron diferencias significativas frente al grupo control (pThe aim of this work was to evaluate the acaricide efficacy of Oxavar® to control Varroa destructor (Anderson & Trueman in Apis mellifera (L colonies during the spring 2002 and the autumn 2003. Work was done at “Centro de Extensión Apícola” experimental apiary located in Coronel Vidal, province of Buenos Aires. Twenty Langstroth hives were used divided in two equal groups. The first group received 5 ml of Oxavar® (323 g in 5000 ml of destiled water per comb covered by honeybees and the second one received 5 ml of destiled water. Both groups received three dosages at seven day periods. Dead mites were collected weekly from special floors in order to avoid

Uranium target fragmentation by intermediate and high energy 12C and 20Ne

International Nuclear Information System (INIS)

McGaughey, P.L.; Loveland, W.; Morrissey, D.J.; Aleklett, K.; Seaborg, G.T.

1985-01-01

The authors report herein the final analysis of the measurement of the target fragment production cross sections for nuclides with 24 less than or equal to A less than or equal to 237 from the interaction of 1.0, 3.0, 4.8, and 12 GeV 12 C and 8.0 and 20.0 GeV 20 Ne with 238 U. Isobaric yield distributions deduced from the nuclidic formation cross sections along with predictions of these distributions made using the nuclear firestreak and intranuclear cascade models are shown. Contrary to a previous report no large yields of fragments with 160 less than or equal to A less than or equal to 200 are observed in any reaction. Both the intranuclear cascade model and the nuclear firestreak model satisfactorily predict the observed yields of fragments with A > 60 indicating the general pattern of yields of these fragments is governed by the excitation energy deposited in the nucleus during the initial projectile-target interaction and the geometry of the collision

Mars Atmospheric Aggregation System API

Data.gov (United States)

National Aeronautics and Space Administration — The {MAAS} API is an open source REST API built to help make it easier and more efficient to build interactive applications that want to utilize the wealth of...

Beebread from Apis mellifera and Apis dorsata. Comparative Chemical Composition and Bioactivity

Directory of Open Access Journals (Sweden)

Otilia BOBIS

2017-05-01

Full Text Available Beebread is a valuable bee product, both for bee nutrition and for humans. The high nutritional and bioactive properties of beebread were evaluated by chemical composition analysis of beebread from Apis mellifera and Apis dorsata. Bee bread harvested from Romania and India, coming from Apis mellifera and Apis dorsata bees, were evaluated for their chemical composition. Analyses were made in APHIS Laboratory from USAMV Cluj, using validated methods for bee products. Lipids were determined by the Soxhlet extraction method, total protein content was determined by Kjehldahl method, sugar spectrum was determined by high performance liquid chromatography with refractive index detection (HPLC-IR. Water content of beebread samples were situated between 11.45 and 16.46%, total protein content between 16.84 and 19.19% and total lipids between 6.36 and 13.47%.  Beebread has high bioactive properties which can be expressed as antioxidant and/or antibacterial activity. Chemical composition and bioactive properties of beebread is influenced by floral origin of the pollen which the bees collect and place in combs for fermentation. Also the climatic conditions have an important role in developing different fermentation compounds, that may act as antioxidants or antibacterial agents.

Alpha-chain states in 4N-nuclei from 20Ne to 32S

International Nuclear Information System (INIS)

Merchant, A.C.; Rae, W.D.M.

1992-01-01

A 6α-chain state has recently been discovered in 24 Mg which is some 16--17 MeV above the 6α-breakup threshold and yet paradoxically only 4--5 MeV wide. This surprising discovery raises the question of the possible existence of Nα-chain states in other 4N-nuclei. The excitation energy of this 6α-chain state is very close to the value predicted by the Bloch-Brink cluster model. Therefore, to aid the experimental search for similar states in other nuclei, we present here predictions of the excitation energies of the Nα-chain state bandheads in the 4N-nuclei from 20 Ne to 32 S obtained using the Bloch-Brink cranked cluster model with the Brink-Boeker effective interaction and free variation of all parameters

Physicochemical analysis of apis dorsata honey from terai forests, Nepal

International Nuclear Information System (INIS)

Qamer, S.; Ahmad, F.; Latif, F.; Ali, S.S

2008-01-01

The multi floral honey produced by Apis dorsata from Shahabgunj, Dhakeri, Narayanpur and Perari forest, Nepal, were provided by International Center for Integrated Mountain Development (ICIMOD), Nepal. These ninety nine Apis dorsata honey samples were characterized physicochemical and were found to have values of various quality determining parameters well with in the permissible International standards. The honey samples had pH in the range of 3.8-4.68, free acidity 41-48 meq/kg, lactones 13-16 meq/kg, total acidity 55-65 meq/kg, moisture content 20.5-26%, electrical conductivity 0.22-0.63 mS/cm, proline content 76-160 mg/kg, HMF content 30-56 mg/kg, diastase number 5.1-29 DN, invertase number 390-499, apparent reducing sugars 73.78-77.78%, fructose 36.93-44.61%, glucose 19.61-27.51% and sucrose 12.07-20.38%. (author)

Updated API document 6A will close API-ISO 9000 gap. [Oil and gas wellhead standards

Energy Technology Data Exchange (ETDEWEB)

Bell, S.

1993-10-01

The 17th edition of the American Petroleum Institute's (API) document 6A, covering wellheads and their components, is due early next year. As the API vs. International Standards Organization (ISO) 9000 struggle continues, this edition of 6A eliminates some unnecessary specifications, clarifies others, and includes metric specifications accepted by the ISO. The 17th edition will clarify some of the interpretations from earlier editions and further advise users how to acquire the API monogram. The goal of this edition is to make 6A acceptable to ISO as an international document so API can maintain control over petroleum equipment specifications and provide input and guidance in future regulations.

Study of 16O(12C,α20Ne)α for the investigation of carbon-carbon fusion reaction via the Trojan Horse Method

International Nuclear Information System (INIS)

Rapisarda, G.G.; Spitaleri, C; Kiss, G.G.; La Cognata, M.; Pizzone, R.G.; Romano, S.; Tumino, A.; Bordeanu, C.; Nita, C.; Pantelica, D.; Petrascu, H.; Velisa, G.; Hons, Z.; Mrazek, J.; Szücs, T.; Trache, L.

2016-01-01

Carbon-carbon fusion reaction represents a nuclear process of great interest in astrophysics, since the carbon burning is connected with the third phase of massive stars (M > 8 M ☉ ) evolution. In spite of several experimental works, carbon-carbon cross section has been measured at energy still above the Gamow window moreover data at low energy present big uncertainty. In this paper we report the results about the study of the 16 O( 12 C,α 20 Ne)α reaction as a possible three-body process to investigate 12 C( 12 C,α) 20 Ne at astrophysical energy via Trojan Horse Method (THM). This study represents the first step of a program of experiments aimed to measure the 12 C+ 12 C cross section at astrophysical energy using the THM. (paper)

Letter of intent for KM3NeT 2.0

NARCIS (Netherlands)

Adrián-Martínez, S.; Ageron, M.; Aharonian, F.; Aiello, S.; Albert, A.; Ameli, F.; Anassontzis, E.; Andre, M.; Androulakis, G.; Anghinolfi, M.; Anton, G.; Ardid, M.; Avgitas, T.; Barbarino, G.; Barbarito, E.; Baret, B.; Barrios-Martí, J.; Belhorma, B.; Belias, A.; Berbee, E.; Berg, A. van den; Bertin, V.; Beurthey, S.; Beveren, V. van; Beverini, N.; Biagi, S.; Biagioni, A.; Billault, M.; Bondì, M.; Bormuth, R.; Bouhadef, B.; Bourlis, G.; Bourret, S.; Boutonnet, C.; Bouwhuis, M.; Bozza, C.; Bruijn, R.; Brunner, J.; Buis, E.J.; Busto, J.; Cacopardo, G.; Caillat, L.; Calamai, M.; Calvo, D.; Capone, A.; Caramete, L.; Cecchini, S.; Celli, S.; Champion, C.; El Moursli, R.C.; Cherubini, S.; Chiarusi, T.; Circella, M.; Classen, L.; Cocimano, R.; Coelho, J.A.B.; Coleiro, A.; Colonges, S.; Coniglione, R.; Cordelli, M.; Cosquer, A.; Coyle, P.; Creusot, A.; Cuttone, G.; D'Amico, A.; De Bonis, G.; De Rosa, G.; De Sio, C.; Di Capua, F.; Di Palma, I.; Díaz García, A.F.; Distefano, C.; Donzaud, C.; Dornic, D.; Dorosti-Hasankiadeh, Q.; Drakopoulou, E.; Drouhin, D.; Drury, L.; Durocher, M.; Eberl, T.; Eichie, S.; Eijk, D. van; El Bojaddaini, I.; El Khayati, N.; Elsaesser, D.; Enzenhöfer, A.; Fassi, F.; Favali, P.; Fermani, P.; Ferrara, G.; Filippidis, C.; Frascadore, G.; Fusco, L.A.; Gal, T.; Galatà, S.; Garufi, F.; Gay, P.; Gebyehu, M.; Giordano, V.; Gizani, N.; Gracia, R.; Graf, K.; Grégoire, T.; Grella, G.; Habel, R.; Hallmann, S.; Haren, H. van; Harissopulos, S.; Heid, T.; Heijboer, A.; Heine, E.; Henry, S.; Hernández-Rey, J.J.; Hevinga, M.; Hofestädt, J.; Hugon, C.M.F.; Illuminati, G.; James, C.W.; Jansweijer, P.; Jongen, M.; Jong, M. de; Kadler, M.; Kalekin, O.; Kappes, A.; Katz, U.F.; Keller, P.; Kieft, G.; Kießling, D.; Koffeman, E.N.; Kooijman, P.; Kouchner, A.; Kulikovskiy, V.; Lahmann, R.; Lamare, P.; Leisos, A.; Leonora, E.; Clark, M.L.; Liolios, A.; Alvarez, C.D.L.; Lo Presti, D.; Löhner, H.; Lonardo, A.; Lotze, M.; Loucatos, S.; MacCioni, E.; Mannheim, K.; Margiotta, A.; Marinelli, A.; Maris, O.; Markou, C.; Martínez-Mora, J.A.; Martini, A.; Mele, R.; Melis, K.W.; Michael, T.; Migliozzi, P.; Migneco, E.; Mijakowski, P.; Miraglia, A.; Mollo, C.M.; Mongelli, M.; Morganti, M.; Moussa, A.; Musico, P.; Musumeci, M.; Navas, S.; Nicolau, C.A.; Olcina, I.; Olivetto, C.; Orlando, A.; Papaikonomou, A.; Papaleo, R.; Pavalas, G.E.; Peek, H.; Pellegrino, C.; Perrina, C.; Pfutzner, M.; Piattelli, P.; Pikounis, K.; Poma, G.E.; Popa, V.; Pradier, T.; Pratolongo, F.; Pühlhofer, G.; Pulvirenti, S.; Quinn, L.; Racca, C.; Raffaelli, F.; Randazzo, N.; Rapidis, P.; Razis, P.; Real, D.; Resvanis, L.; Reubelt, J.; Riccobene, G.; Rossi, C.; Rovelli, A.; Saldaña, M.; Salvadori, I.; Samtleben, D.F.E.; García, A.S.; Losa, A.S.; Sanguineti, M.; Santangelo, A.; Santonocito, D.; Sapienza, P.; Schimmel, F.; Schmelling, J.; Sciacca, V.; Sedita, M.; Seitz, T.; Sgura, I.; Simeone, F.; Siotis, I.; Sipala, V.; Spisso, B.; Spurio, M.; Stavropoulos, G.; Steijger, J.; Stellacci, S.M.; Stransky, D.; Taiuti, M.; Tayalati, Y.; Tézier, D.; Theraube, S.; Thompson, L.; Timmer, P.; Tönnis, C.; Trasatti, L.; Trovato, A.; Tsirigotis, A.; Tzamarias, S.; Tzamariudaki, E.; Vallage, B.; Elewyck, V. van; Vermeulen, J.; Vicini, P.; Viola, S.; Vivolo, D.; Volkert, M.; Voulgaris, G.; Wiggers, L.; Wilms, J.; De Wolf, E.; Zachariadou, K.; Zornoza, J.D.; Zúñiga, J.

2016-01-01

The main objectives of the KM3NeT Collaboration are (i) the discovery and subsequent observation of high-energy neutrino sources in the Universe and (ii) the determination of the mass hierarchy of neutrinos. These objectives are strongly motivated by two recent important discoveries, namely: (1) the

Letter of intent for KM3NeT 2.0

NARCIS (Netherlands)

Adrián-Martínez, S.; Ageron, M.; Aharonian, F.; Aiello, S.; Albert, A.; Ameli, F.; Anassontzis, E.; Andre, M.; Androulakis, G.; Anghinolfi, M.; Anton, G.; Ardid, M.; Avgitas, T.; Barbarino, G.; Barbarito, E.; Baret, B.; Barrios-Martí, J.; Belhorma, B.; Belias, A.; Berbee, E.; van den Berg, A.; Bertin, V.; Beurthey, S.; van Beveren, V.; Beverini, N.; Biagi, S.; Biagioni, A.; Billault, M.; Bondi, M.; Bormuth, R.; Bouhadef, B.; Bourlis, G.; Bourret, S.; Boutonnet, C.; Bouwhuis, M.; Bozza, C.; Bruijn, R.; Brunner, J.; Buis, E.; Busto, J.; Cacopardo, G.; Caillat, L.; Calamai, M.; Calvo, D.; Capone, A.; Caramete, L.; Cecchini, S.; Celli, S.; Champion, C.; Cherkaoui El Moursli, R.; Cherubini, S.; Chiarusi, T.; Circella, M.; Classen, L.; Cocimano, R.; Coelho, J.A.B.; Coleiro, A.; Colonges, S.; Coniglione, R.; Cordelli, M.; Cosquer, A.; Coyle, P.; Creusot, A.; Cuttone, G.; D'Amico, A.; De Bonis, G.; De Rosa, G.; De Sio, C.; Di Capua, F.; Di Palma, I.; Díaz García, A.F.; Distefano, C.; Donzaud, C.; Dornic, D.; Dorosti-Hasankiadeh, Q.; Drakopoulou, E.; Drouhin, D.; Drury, L.; Durocher, M.; Eberl, T.; Eichie, S.; van Eijk, D.; El Bojaddaini, I.; El Khayati, N.; Elsaesser, D.; Enzenhöfer, A.; Fassi, F.; Favali, P.; Fermani, P.; Ferrara, G.; Filippidis, C.; Frascadore, G.; Fusco, L.A.; Gal, T.; Galatà, S.; Garufi, F.; Gay, P.; Gebyehu, M.; Giordano, V.; Gizani, N.; Gracia, R.; Graf, K.; Grégoire, T.; Grella, G.; Habel, R.; Hallmann, S.; van Haren, H.; Harissopulos, S.; Heid, T.; Heijboer, A.; Heine, E.; Henry, S.; Hernández-Rey, J.J.; Hevinga, M.; Hofestädt, J.; Hugon, C.M.F.; Illuminati, G.; James, C.W.; Jansweijer, P.; Jongen, M.; de Jong, M.; Kadler, M.; Kalekin, O.; Kappes, A.; Katz, U.F.; Keller, P.; Kieft, G.; Kießling, D.; Koffeman, E.N.; Kooijman, P.; Kouchner, A.; Kulikovskiy, V.; Lahmann, R.; Lamare, P.; Leisos, A.; Leonora, E.; Lindsey Clark, M.; Liolios, A.; Llorens Alvarez, C.D.; Lo Presti, D.; Löhner, H.; Lonardo, A.; Lotze, M.; Loucatos, S.; Maccioni, E.; Mannheim, K.; Margiotta, A.; Marinelli, A.; Mariş, O.; Markou, C.; Martínez-Mora, J.A.; Martini, A.; Mele, R.; Melis, K.W.; Michael, T.; Migliozzi, P.; Migneco, E.; Mijakowski, P.; Miraglia, A.; Mollo, C.M.; Mongelli, M.; Morganti, M.; Moussa, A.; Musico, P.; Musumeci, M.; Navas, S.; Nicolau, C.A.; Olcina, I.; Olivetto, C.; Orlando, A.; Papaikonomou, A.; Papaleo, R.; Păvălaş, G.E.; Peek, H.; Pellegrino, C.; Perrina, C.; Pfutzner, M.; Piattelli, P.; Pikounis, K.; Poma, G.E.; Popa, V.; Pradier, T.; Pratolongo, F.; Pühlhofer, G.; Pulvirenti, S.; Quinn, L.; Racca, C.; Raffaelli, F.; Randazzo, N.; Rapidis, P.; Razis, P.; Real, D.; Resvanis, L.; Reubelt, J.; Riccobene, G.; Rossi, C.; Rovelli, A.; Saldaña, M.; Salvadori, I.; Samtleben, D.F.E.; Sánchez García, A.; Sánchez Losa, A.; Sanguineti, M.; Santangelo, A.; Santonocito, D.; Sapienza, P.; Schimmel, F.; Schmelling, J.; Sciacca, V.; Sedita, M.; Seitz, T.; Sgura, I.; Simeone, F.; Siotis, I.; Sipala, V.; Spisso, B.; Spurio, M.; Stavropoulos, G.; Steijger, J.; Stellacci, S.M.; Stransky, D.; Taiuti, M.; Tayalati, Y.; Tézier, D.; Theraube, S.; Thompson, L.; Timmer, P.; Tönnis, C.; Trasatti, L.; Trovato, A.; Tsirigotis, A.; Tzamarias, S.; Tzamariudaki, E.; Vallage, B.; Van Elewyck, V.; Vermeulen, J.; Vicini, P.; Viola, S.; Vivolo, D.; Volkert, M.; Voulgaris, G.; Wiggers, L.; Wilms, J.; de Wolf, E.; Zachariadou, K.; Zornoza, J.D.; Zúñiga, J.

The main objectives of the KM3NeT Collaboration are (i) the discovery and subsequent observation of high-energy neutrino sources in the Universe and (ii) the determination of the mass hierarchy of neutrinos. These objectives are strongly motivated by two recent important discoveries, namely: (1) the

Intro to the Zotero API

Directory of Open Access Journals (Sweden)

Amanda Morton

2013-04-01

Full Text Available In this lesson, you’ll learn how to use python with the Zotero API to interact with your Zotero library. The Zotero API is a powerful interface that would allow you to build a complete Zotero client from scratch if you so desired. But like most APIs, it works in small, discrete steps, so we have to build our way up to the complicated requests we might want to use to access our Zotero libraries. But this incremental building gives us plenty of time to learn as we go along.

Bluetooth API Implementation into Android

Directory of Open Access Journals (Sweden)

Konev Sergey

2017-01-01

Full Text Available Bluetooth is a popular method of communication between devices. Many smartphones today have the capability to communicate using Bluetooth. Android developers sometimes need to use Bluetooth in their projects. Android OS provides a powerful API for Bluetooth that allows to simplify scanning the environment for devices, pairing and connecting, data transfer between devices and more. However, utilizing the Bluetooth API can be difficult for first-time users. The objective of this article is to demonstrate the key points of implementing Bluetooth API in the Android application.

Restful API Architecture Based on Laravel Framework

Science.gov (United States)

Chen, Xianjun; Ji, Zhoupeng; Fan, Yu; Zhan, Yongsong

2017-10-01

Web service has been an industry standard tech for message communication and integration between heterogeneous systems. RESTFUL API has become mainstream web service development paradigm after SOAP, how to effectively construct RESTFUL API remains a research hotspots. This paper presents a development model of RESTFUL API construction based on PHP language and LARAVEL framework. The key technical problems that need to be solved during the construction of RESTFUL API are discussed, and implementation details based on LARAVEL are given.

Programa Nordeste para transplante cardiaco "NE-Tx": experiência atual NE-Tx North East Brazil heart transplant program: current-experience

Directory of Open Access Journals (Sweden)

Ricardo Lima

1992-09-01

Full Text Available Os autores relatam a presente experiência clínica do programa NE-Tx, que é integrado por quatro diferentes Centros, bem como suas peculiaridades regionais. Foi idealizado um programa com baixo custo e integração regional. Na investigação pré-operatória, foi valorizado o nível social e intelectual do receptor e sua relação com os familiares. A busca de órgão à distância foi suprimida, com o deslocamento do receptor até o local da disponibilidade do órgáo. No pós-operatório não se utilizou dosagem sérica de ciclosporina, tendo os pacientes sido controlados com monitorização seriada da função renal. Com essa estratégia, foram operados 7 pacientes, no período compreendido entre 19.7.86 e 1.11.91., em três diferentes Centros Integrados. Todos eram do sexo masculino e a idade variou de 17 a 50 anos. Três (42,8% pacientes eram portadores de miocardiopatiachagásica, 2 (28,5% de miocardiopatiaidiopática, 1 (14,3% de miocardiopatia hipertrófica e 1 (14,3% de miocardiopatia reumática. Três (42,8% pacientes vieram de Centros diferentes: 1 de Natal para Recife, 1 de Maceió para Aracaju e um terceiro de Aracaju para Maceió. Dois (28,6% pacientes faleceram: um no período de pós-operatório imediato, de maneira ignorada e outro no pós-operatório tardio, devido a crise de rejeição. A mortalidade imediata foi de 14,3% e a tardia de 14,3%. Os restantes 5 (71,4% pacientes encontram-se evoluindo bem, tendo o follow-up variado de 2 a 48 meses. A incidência de infecção, rejeição e demais problemas relacionados com o pós-operatório tardio é superponível com outros Centros. O programa mostrou-se eficiente, prático, compatível com nossa realidade e reproduz resultados de outras experiências.The authors report their current clinical experience with the "NE-Tx" program, which covers four different centres, as well as its regional peculiarities. The program was designed to be of low cost and regionally integrated. In

Neutral strange-particle production in anti p 20Ne reactions at 607 MeV/c

International Nuclear Information System (INIS)

Balestra, F.; Bussa, M.P.; Busso, L.; Fava, L.; Ferrero, L.; Panzieri, D.; Piragino, G.; Tosello, F.; Bendiscioli, G.; Rotondi, A.; Salvini, P.; Zenoni, A.; Batusov, Yu.A.; Falomkin, I.V.; Pontecorvo, G.B.; Sapozhnikow, M.G.; Tretyak, V.I.; Guaraldo, C.; Maggiora, A.; Haatuft, A.; Halsteinslid, A.; Myklebost, K.; Olsen, J.M.; Breivik, F.O.; Jacobsen, T.; Soerensen, S.O.

1987-01-01

The Λ 0 and K 0 s production cross sections have been measured at 607 MeV/c for the reaction anti p + 20 Ne → V 0 + X (V 0 = Λ 0 , K s 0 ). The Λ 0 /K s 0 production ratio is found to be (2.3 ± 0.7). The data are consistent with an evaporative character of the emission mechanism from a multinucleon system for Λ 0 and from one nucleon K s 0 . The rapidity distributions of negative tracks in K s 0 events are different from those in Λ 0 events and events without V 0 . (orig.)

The g-factor of the first excited 4+ state in 20Ne from transient field precession measurement in gadolinium

International Nuclear Information System (INIS)

Tandon, P.N.; Speidel, K.H.; Mertens, V.; Trolenberg, W.; Kumbartzki, G.S.; Ayres de Campos, N.; Goldberg, M.B.; Gerber, J.; Toulemonde, M.

1981-01-01

The g-factor of the 4 + state in 20 Ne at 4.25 MeV has been obtained to be g = +0.08(20) from transient field precession measurements in Gd in agreement with the present authors' earlier reported value of g =- 0.10(19) (1980). The significant reduction in the value of the g- factor, g = -0.01(14), relative to that of the 2 + state (g = + 0.54(4))(1975) is in complete disagreement with theory. In addition the life time of the 4 + state has been measured to be tau = 95(13) fs. (author)

Investigation of complete and incomplete fusion in 20Ne + 51V system using recoil range measurement

Directory of Open Access Journals (Sweden)

Ali Sabir

2015-01-01

Full Text Available Recoil range distributions of evaporation residues, populated in 20Ne + 51V reaction at Elab ≈ 145 MeV, have been studied to determine the degree of momentum transferred through the complete and incomplete fusion reactions. Evaporation residues (ERs populated through the complete and incomplete fusion reactions have been identified on the basis of their recoil range in the Al catcher medium. Measured recoil range of evaporation residues have been compared with the theoretical value calculated using the code SRIM. Range integrated cross section of observed ERs have been compared with the value predicted by statistical model code PACE4.

Infra-Population and -Community Dynamics of the Parasites Nosema apis and Nosema ceranae, and Consequences for Honey Bee (Apis mellifera) Hosts

Science.gov (United States)

Williams, Geoffrey R.; Shutler, Dave; Burgher-MacLellan, Karen L.; Rogers, Richard E. L.

2014-01-01

Nosema spp. fungal gut parasites are among myriad possible explanations for contemporary increased mortality of western honey bees (Apis mellifera, hereafter honey bee) in many regions of the world. Invasive Nosema ceranae is particularly worrisome because some evidence suggests it has greater virulence than its congener N. apis. N. ceranae appears to have recently switched hosts from Asian honey bees (Apis cerana) and now has a nearly global distribution in honey bees, apparently displacing N. apis. We examined parasite reproduction and effects of N. apis, N. ceranae, and mixed Nosema infections on honey bee hosts in laboratory experiments. Both infection intensity and honey bee mortality were significantly greater for N. ceranae than for N. apis or mixed infections; mixed infection resulted in mortality similar to N. apis parasitism and reduced spore intensity, possibly due to inter-specific competition. This is the first long-term laboratory study to demonstrate lethal consequences of N. apis and N. ceranae and mixed Nosema parasitism in honey bees, and suggests that differences in reproduction and intra-host competition may explain apparent heterogeneous exclusion of the historic parasite by the invasive species. PMID:24987989

Infra-population and -community dynamics of the parasites Nosema apis and Nosema ceranae, and consequences for honey bee (Apis mellifera) hosts.

Science.gov (United States)

Williams, Geoffrey R; Shutler, Dave; Burgher-MacLellan, Karen L; Rogers, Richard E L

2014-01-01

Nosema spp. fungal gut parasites are among myriad possible explanations for contemporary increased mortality of western honey bees (Apis mellifera, hereafter honey bee) in many regions of the world. Invasive Nosema ceranae is particularly worrisome because some evidence suggests it has greater virulence than its congener N. apis. N. ceranae appears to have recently switched hosts from Asian honey bees (Apis cerana) and now has a nearly global distribution in honey bees, apparently displacing N. apis. We examined parasite reproduction and effects of N. apis, N. ceranae, and mixed Nosema infections on honey bee hosts in laboratory experiments. Both infection intensity and honey bee mortality were significantly greater for N. ceranae than for N. apis or mixed infections; mixed infection resulted in mortality similar to N. apis parasitism and reduced spore intensity, possibly due to inter-specific competition. This is the first long-term laboratory study to demonstrate lethal consequences of N. apis and N. ceranae and mixed Nosema parasitism in honey bees, and suggests that differences in reproduction and intra-host competition may explain apparent heterogeneous exclusion of the historic parasite by the invasive species.

Reaction cross section for Ne isotopes

International Nuclear Information System (INIS)

Panda, R.N.; Sahu, B.K.; Patra, S.K.

2012-01-01

In the present contribution, first the bulk properties are calculated, such as binding energy (BE), root mean square charge radius r ch , matter radius r m and quadrupole deformation parameter β 2 for 18-32 Ne isotopes in the Relativistic mean field (RMF) and effective field theory motivated RMF (E-RMF) formalisms . Then the total nuclear reaction cross section σR is analyzes for the scattering of 20 Ne and 28-32 Ne from a 12 C target at 240 MeV/nucleon by using the RMF model. Thus the objective of the present study is to calculate the bulk properties as well as a systematic analysis of σR over a range of neutron rich nuclei in the frame work of Glauber model

TUMBUHAN YANG DIKUNJUNGI LEBAH PEKERJA Apis (Hymenoptera: Apidae DI SUMATERA BARAT

Directory of Open Access Journals (Sweden)

Jasmi Jasmi

2016-09-01

Full Text Available Research about plant visited by Apis forager was conducted at altitude < 500 m and 600-1400 m of West Sumatra from December 2009-July 2010. The plant visited by forager was collected at radius 500 m from nests in fruits cropping, coffea and cinnamom plantation and forest edge. Honeybee from genus Apisvisit on plant consisted of four species, those are A. andreniformis, A. cerana, A. dorsata and A. koschevnikovi. Plant visited by forager Apis consisted of 61 species belong to 26 families. The number of 36 plant species found at lowland and highland, 20 species only at lowland and five species at highland. Most of plant species visited by Apis forager are Asteraceae and Leguminoceae. About 29 plant species visited by Apis were agriculture crop and 32 species of non agriculture. Apis andreniformis visited 29 plant species, A. cerana 56 species, A. dorsata 57 species and A. koschevnikovi one plant species. Cucumis sativus was visited by four bee species, Galiansoga farviflora was visited only by A. cerana. Five plant species (Rorippa indica, Cinnamomum burmanii, Nasturrium indicum, Rorippa indica and Eryngium foetidum were visited by only A. dorsata. Other three plants species (Mangifera indica, Cytrus aurantifoliaand Oryza sativa were visited by A. cerana and A. andreniformis, 31 plant species were visited by A. cerana and A. dorsata, 21 species were visited by A. andreniformis, A. cerana and A. dorsata. Keywords: lebah madu, Apis forager, food source plant, visit

Web API Growing Pains : Loosely Coupled yet Strongly Tied

NARCIS (Netherlands)

Espinha, T.; Zaidman, A.; Gross, H.G.

2014-01-01

Web APIs provide a systematic and extensible approach for application-toapplication interaction. Developers using web APIs are forced to accompany the API providers in their software evolution tasks. In order to understand the distress caused by this imposition on web API client developers we

Jobs API

Data.gov (United States)

General Services Administration — This Jobs API returns job openings across the federal government and includes all current openings posted on USAJobs.gov that are open to the public and located in...

Ne recorderis: Música y liturgia fúnebres en la catedral de Ourense para las honras del cardenal D. Pedro Quevedo y Quintano (+ 1818)

OpenAIRE

Garbayo Montabes, Francisco Javier

2012-01-01

Durante el Pontificado ourensano del Cardenal Quevedo, ejerció de maestro de capilla en la cate­ dral-Basílica de San Martín, el organista y compositor Joaquín Pedrosa Gil. Entre su abundante producción, guardada en el Archivo de Música de la catedral, se conserva un Responso IV, Ne recorderis, para los solemnes funerales que el comercio de la ciudad ofreció a su Prelado, con todo el boato y aparato ceremonial que había marcado este tipo de acontecimientos durante la pervi­ ...

Recalls API

Data.gov (United States)

General Services Administration — This Recalls API allows you to tap into a list of (1) drug and food safety recalls from the Food and Drug Administration, Food Safety and Inspection Service, and...

Improving the API dissolution rate during pharmaceutical hot-melt extrusion I: Effect of the API particle size, and the co-rotating, twin-screw extruder screw configuration on the API dissolution rate.

Science.gov (United States)

Li, Meng; Gogos, Costas G; Ioannidis, Nicolas

2015-01-15

The dissolution rate of the active pharmaceutical ingredients in pharmaceutical hot-melt extrusion is the most critical elementary step during the extrusion of amorphous solid solutions - total dissolution has to be achieved within the short residence time in the extruder. Dissolution and dissolution rates are affected by process, material and equipment variables. In this work, we examine the effect of one of the material variables and one of the equipment variables, namely, the API particle size and extruder screw configuration on the API dissolution rate, in a co-rotating, twin-screw extruder. By rapidly removing the extruder screws from the barrel after achieving a steady state, we collected samples along the length of the extruder screws that were characterized by polarized optical microscopy (POM) and differential scanning calorimetry (DSC) to determine the amount of undissolved API. Analyses of samples indicate that reduction of particle size of the API and appropriate selection of screw design can markedly improve the dissolution rate of the API during extrusion. In addition, angle of repose measurements and light microscopy images show that the reduction of particle size of the API can improve the flowability of the physical mixture feed and the adhesiveness between its components, respectively, through dry coating of the polymer particles by the API particles. Copyright © 2014. Published by Elsevier B.V.

fine-GRAPE : Fine-grained APi usage extractor – an approach and dataset to investigate API usage

NARCIS (Netherlands)

Sawant, A.A.; Bacchelli, A.

An Application Programming Interface (API) provides a set of functionalities to a developer with the aim of enabling reuse. APIs have been investigated from different angles such as popularity usage and evolution to get a better understanding of their various characteristics. For such studies,

Effects of Nosema apis, N. ceranae, and coinfections on honey bee (Apis mellifera) learning and memory.

Science.gov (United States)

Charbonneau, Lise R; Hillier, Neil Kirk; Rogers, Richard E L; Williams, Geoffrey R; Shutler, Dave

2016-03-10

Western honey bees (Apis mellifera) face an increasing number of challenges that in recent years have led to significant economic effects on apiculture, with attendant consequences for agriculture. Nosemosis is a fungal infection of honey bees caused by either Nosema apis or N. ceranae. The putative greater virulence of N. ceranae has spurred interest in understanding how it differs from N. apis. Little is known of effects of N. apis or N. ceranae on honey bee learning and memory. Following a Pavlovian model that relies on the proboscis extension reflex, we compared acquisition learning and long-term memory recall of uninfected (control) honey bees versus those inoculated with N. apis, N. ceranae, or both. We also tested whether spore intensity was associated with variation in learning and memory. Neither learning nor memory differed among treatments. There was no evidence of a relationship between spore intensity and learning, and only limited evidence of a negative effect on memory; this occurred only in the co-inoculation treatment. Our results suggest that if Nosema spp. are contributing to unusually high colony losses in recent years, the mechanism by which they may affect honey bees is probably not related to effects on learning or memory, at least as assessed by the proboscis extension reflex.

LNG. Practice and policy. Meeting report NeVER, November 20, 2006

International Nuclear Information System (INIS)

Holzhauer, R.W.

2007-01-01

Report is given of a meeting of the Netherlands Association for Energy Legislation (NeVER), which was held November 16, 2006, in Amsterdam, on the subject of LNG. More in particular third party access to LNG-terminals and related exemption regulations in Europe and the Netherlands [nl

Atrativo para as abelhas Apis mellifera e polinização em café (Coffea arabica L.

Directory of Open Access Journals (Sweden)

Darclet Teresinha Malerbo-Souza

2003-01-01

Full Text Available O presente experimento foi conduzido em Jaboticabal, SP, e teve como objetivos estudar uma cultura de café (Coffea arabica L., var. Mundo Novo, quanto à biologia floral, a freqüência e comportamento dos insetos na flor, testar o produto Bee-HereR (Hoescht Shering Agrevo do Brasil Ltda quanto a sua atratividade para as abelhas Apis mellifera e verificar a produção de frutos com e sem a visita dos insetos. Para isso, foram verificados o tempo do desenvolvimento e quantidade de açúcar solúvel do néctar das flores; freqüência das visitações dos insetos, no decorrer do dia, por meio de contagem do número de insetos visitando as flores, a cada 60 minutos, das 8 às 17 horas, 10 minutos em cada horário; tempo (em segundos e tipo de coleta (néctar e/ou pólen dos insetos mais freqüentes; perda de botões florais; porcentagem de flores que se transformaram em frutos; tempo de formação e contagem dos grãos de café, observando-se a porcentagem de frutificação em flores visitadas ou não pelos insetos. Também foram realizados testes por pulverização utilizando-se o produto Bee-HereR , diluído em xarope e em água, em diferentes horários. A flor durou, em média, cerca de 3 dias desde sua abertura até o murchamento. A quantidade de açúcares do néctar apresentou diferença significativa entre os horários, sendo maior às 8 horas (em média, 102,18 ± 8,75 mg de carboidratos totais por flor. A abelha A. mellifera foi o inseto mais freqüente nas flores de café, coletando, principalmente, néctar no decorrer do dia. A perda de botões florais causada pelas chuvas foi, em média, 26,50 ± 11,70%. O tempo para a formação do fruto foi 6 meses e o número de frutos decorrentes do tratamento descoberto foi maior (38,79% e 168,38%, em 1993 e 1994, respectivamente que do tratamento coberto. Apesar da eficiência do produto Bee-HereR ser afetada pelas condições climáticas, ele pode ser usado para atrair as abelhas A. mellifera na

Stellar origin of the 22Ne excess in cosmic rays

International Nuclear Information System (INIS)

Casse, M.; Paul, J.A.

1982-01-01

The 22 Ne excess at the cosmic-ray source is discussed in terms of a 22 Ne-rich component injected and accelerated by carbon-rich Wolf-Rayet stars. The overabundance of 22 Ne relative to 20 Ne predicted at the surface of these stars is estimated to a factor approx.120 with respect to solar system abundances. In order to give rise to a 22 Ne excess of about 3 at the cosmic-ray sources as inferred from observations, the carbon-rich Wolf-Rayet contribution to the primary cosmic-ray flux is to be at maximum 1/60. This component would be energized by strong stellar winds producing quasi-standing shocks around the Wolf-Rayet stars

Continuous API-crystal coating via coacervation in a tubular reactor.

Science.gov (United States)

Besenhard, M O; Thurnberger, A; Hohl, R; Faulhammer, E; Rattenberger, J; Khinast, J G

2014-11-20

We present a proof-of-concept study of a continuous coating process of single API crystals in a tubular reactor using coacervation as a microencapsulation technique. Continuous API crystal coating can have several advantages, as in a single step (following crystallization) individual crystals can be prepared with a functional coating, either to change the release behavior, to protect the API from gastric juice or to modify the surface energetics of the API (i.e., to tailor the hydrophobic/hydrophilic characteristics, flowability or agglomeration tendency, etc.). The coating process was developed for the microencapsulation of a lipophilic core material (ibuprofen crystals of 20 μm- to 100 μm-size), with either hypromellose phthalate (HPMCP) or Eudragit L100-55. The core material was suspended in an aqueous solution containing one of these enteric polymers, fed into the tubing and mixed continuously with a sodium sulfate solution as an antisolvent to induce coacervation. A subsequent temperature treatment was applied to optimize the microencapsulation of crystals via the polymer-rich coacervate phase. Cross-linking of the coating shell was achieved by mixing the processed material with an acidic solution (pH<3). Flow rates, temperature profiles and polymer-to-antisolvent ratios had to be tightly controlled to avoid excessive aggregation, leading to pipe plugging. This work demonstrates the potential of a tubular reactor design for continuous coating applications and is the basis for future work, combining continuous crystallization and coating. Copyright © 2014 Elsevier B.V. All rights reserved.

Plataforma para Auxílio ao Ensino de Programação e Robótica Pedagógica

Directory of Open Access Journals (Sweden)

Vitória Heliane Pereira dos Santos Sobrinha

2016-12-01

Full Text Available Este trabalho descreve uma Application Programming Interface (API, que pode ser utilizada para comunicação e controle de um robô pedagógico. A API foi desenvolvida nas linguagens C++ e Python, que são as primeiras linguagens ensinadas no curso técnico em informática do IFPB Guarabira. Os métodos implementados permitem ao robô andar para frente, andar para trás, virar à direita, virar à esquerda e obter a distância até um obstáculo à frente. A API encapsula toda a complexidade para comunicação e transmissão dos comandos. Junto a ela, está sendo desenvolvida uma Plataforma de Programação Visual  (PPV em Python. Essa plataforma, em conjunto com a API, será utilizada para tornar mais fácil e atrativa a aprendizagem de programação para os alunos iniciantes e alunos surdos. A motivação deste trabalho é utilizar a robótica como uma ferramenta de ensino, ajudando no entendimento de conceitos complexos na área de computação e de outras disciplinas, como física e matemática. Usando a PPV, os alunos poderão aprender com maior facilidade os comandos da linguagem Python, por meio de associação de imagens com os comandos. Devido a essa característica, espera-se que os alunos surdos consigam identificar com maior facilidade os comandos que estão associados às imagens.

Reaction-mechanism evolution for the system 20Ne + 60Ni at intermediate energies: from massive transfer to fragmentation

International Nuclear Information System (INIS)

Andreozzi, F.; Brondi, A.; D'Onofrio, A.; LaRana, G.; Moro, R.; Perillo, E.; Romano, M.; Terrasi, F.; Dayras, R.; Dumont, H.; Gadi, F.; Gomez del Campo, J.

1993-01-01

Mass and charge distributions for heavy residues in the reaction 20 Ne + 60 Ni at 50 MeV/nucleon were measured by in-beam and off-line γ-ray spectrometry. The stacked foil method was used to obtain information about the distribution of the velocity component parallel to the beam direction for target-like residues. The comparison of the data to the predictions of a participant-spectator model indicates that an 8% width for the dissipated energy distribution accounts for the observed projected ranges. (orig.)

Excitation functions for some Ne induced reactions with Holmium: incomplete fusion vs complete fusion

International Nuclear Information System (INIS)

Agarwal, Avinash; Kumar, Munish; Sharma, Anjali; Rizvi, I.A.; Ahamad, Tauseef; Ghugre, S.S.; Sinha, A.K.; Chaubey, A.K.

2010-01-01

Reactions induced by 20 Ne are expected to be considerably more complex than those of 12 C, and 16 O. As a part of the ongoing program to understand CF and ICF reaction mechanisms, it is of great interest to see whether the same experimental technique yield similarly valuable information for 20 Ne induced reactions. In this present work an attempt has been made to measure the excitation functions for fifteen evaporation residues (ERs) identified in the interaction of 20 Ne + 165 Ho system in the energy range 4 -7 MeV/A

Evaluación del sistema Vitek 2 para la identificación de las principales especies de levaduras del género Candida

Directory of Open Access Journals (Sweden)

María E Ochiuzzi

Full Text Available El objetivo del trabajo fue evaluar el desempeño de las tarjetas YST del sistema Vitek 2 para la identificación de levaduras del género Candida. Se analizaron 168 aislamientos; los resultados fueron comparados con los obtenidos por los equipos API 20C AUX (24 % o API ID 32C (76 %. Cada cepa se subcultivó en agar cromogénico para levaduras y se observó la micromorfología. C. albicans y C. dubliniensis fueron identificadas a través de pruebas bioquímicas y moleculares adicionales. La concordancia observada fue del 98,3 %. Solo tres cepas no fueron identificadas correctamente por el sistema Vitek 2: una cepa de C. tropicalis y una de C. krusei fueron identificadas erróneamente como C. parapsilosis y otra cepa de C. krusei fue identificada de manera incompleta por el software del equipo. El tiempo promedio de identificación con las tarjetas YST fue de 18,25 h. El sistema Vitek 2 surge como un método confiable, simple y efectivo para la identificación de las principales especies del género Candida.

DySectAPI: Scalable Prescriptive Debugging

DEFF Research Database (Denmark)

Jensen, Nicklas Bo; Karlsson, Sven; Quarfot Nielsen, Niklas

We present the DySectAPI, a tool that allow users to construct probe trees for automatic, event-driven debugging at scale. The traditional, interactive debugging model, whereby users manually step through and inspect their application, does not scale well even for current supercomputers. While...... lightweight debugging models scale well, they can currently only debug a subset of bug classes. DySectAPI fills the gap between these two approaches with a novel user-guided approach. Using both experimental results and analytical modeling we show how DySectAPI scales and can run with a low overhead...

APIs and Researchers: The Emperor's New Clothes?

Directory of Open Access Journals (Sweden)

Jennifer Edmond

2015-02-01

Full Text Available As part of the Europeana Cloud (eCloud project, Trinity College Dublin investigated best practice in the use of web services, such as APIs, for accessing large data sets from cultural heritage collections. This research looked into the provision and use of APIs, and moreover, whether or not more customised programmatic access to datasets is what researchers want or need. In order to understand whether current patterns of API usage reflect a skills gap on the part of researchers or a mismatch of tool to purpose, we looked not only at the creators and developer/users of APIs, but also at humanists already re-using big data; approaches in cultural heritage institutions and other research infrastructures to bring API use to non-technical audiences; and the kinds of training and other support services available or emerging within the data-intensive humanities research lifecycle. We conducted both desk research and a series of 11 interviews with figures working as researchers, developers or data providers, including figures from both the API development and the data usage communities. This research, conducted under the eCloud project and supported by the European Commission’s ICT Policy and Support Programme (Grant number 325091, was begun in March 2014 and is now in its concluding validation stage. The results of the research are not yet finalised, but the contribution is already emerging of this work to the debate about APIs being either the way forward for digital cultural heritage collections, or the Emperor’s New Clothes (or maybe a bit of both.

USAJOBS Job Opportunity Announcements (JOA) REST API

Data.gov (United States)

Office of Personnel Management — This REST-based API is designed to support lightweight Federal Job Opportunity Announcement (JOA) content consumption by consumers. It is anticipated that this API...

47 CFR 61.46 - Adjustments to the API.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 3 2010-10-01 2010-10-01 false Adjustments to the API. 61.46 Section 61.46... Rules for Dominant Carriers § 61.46 Adjustments to the API. (a) Except as provided in paragraphs (d) and... carrier must calculate an API for each affected basket pursuant to the following methodology: APIt = APIt...

Dielektrične lastnosti vodnih raztopin nekaterih mono- in polisaharidov

OpenAIRE

Gubenšek, Špela

2017-01-01

V magistrskem delu smo raztopinam različnih saharidov določali dielektrične lastnosti. Analizirali smo vodne raztopine glukoze, fruktoze, inulina, dekstrina, maltodekstrina, oligofruktoze in glukozno-fruktoznega sirupa. Saharide smo okarakterizirali tako, da smo določili njihove reducirajoče lastnosti in v glukozno-fruktoznem sirupu delež fruktoze. Za določanje dielektrične konstante v območju frekvenc izmenične napetosti med 20 kHz in 2 MHz smo uporabili kapacitivno metodo in LCR merilnik. ...

Mass distribution of fission-like fragments formed in 20Ne + 165Ho system at Elab≈ 8.2 MeV/A

International Nuclear Information System (INIS)

Singh, D.; Linda, Sneha Bharti; Giri, Pankaj K.

2017-01-01

In the present work, an attempt has been made to study CFF and IFF in 20 Ne + 165 Ho system at projectile energy ≈ 8.2 MeV/A. Twelve fission like fragments (FLF) produced through complete fusion-fission (CFF) and/or incomplete fusion-fission (IFF) in the present system have been identified. The production cross-sections of identified fission like fragments have been measured and the mass distribution of fission like fragments studied

Cross measurements of linear momentum transfer and energy dissipation in collisions between 290 MeV 20Ne and 238U

International Nuclear Information System (INIS)

Galin, J.; Ingold, G.; Jahnke, U.; Hilscher, D.; Lehmann, M.; Rossner, H.; Schwinn, E.

1988-01-01

The 20 Ne+U reactions are investigated at 290 MeV bombarding energy. The linear momentum transfer and excitation energy are deduced eventwise from the respective measurements of the folding angle between correlated fission fragments and the neutron multiplicity. A simple incomplete fusion picture is shown to essentially account for the data. The sensitivity of the two measurements in order to infer the violence of a collision is discussed in details. (orig.)

Dry coating of micronized API powders for improved dissolution of directly compacted tablets with high drug loading.

Science.gov (United States)

Han, Xi; Ghoroi, Chinmay; Davé, Rajesh

2013-02-14

Motivated by our recent study showing improved flow and dissolution rate of the active pharmaceutical ingredient (API) powders (20 μm) produced via simultaneous micronization and surface modification through continuous fluid energy milling (FEM) process, the performance of blends and direct compacted tablets with high drug loading is examined. Performance of 50 μm API powders dry coated without micronization is also considered for comparison. Blends of micronized, non-micronized, dry coated or uncoated API powders at 30, 60 and 70% drug loading, are examined. The results show that the blends containing dry coated API powders, even micronized ones, have excellent flowability and high bulk density compared to the blends containing uncoated API, which are required for direct compaction. As the drug loading increases, the difference between dry coated and uncoated blends is more pronounced, as seen in the proposed bulk density-FFC phase map. Dry coating led to improved tablet compactibility profiles, corresponding with the improvements in blend compressibility. The most significant advantage is in tablet dissolution where for all drug loadings, the t(80) for the tablets with dry coated APIs was well under 5 min, indicating that this approach can produce nearly instant release direct compacted tablets at high drug loadings. Copyright © 2012 Elsevier B.V. All rights reserved.

Estudo do efeito da tensão sobre a permeação por Hidrogênio em Aços API 5L X60 e API 5L X65

Directory of Open Access Journals (Sweden)

Bruno Araújo Araújo

2017-12-01

Full Text Available Under operating conditions, the oil and gas transmission pipelines can be subjected to high pressures and, at the same time, suffer the effect of acidic substances in the transported hydrocarbons such as H2S, whose action alone or combined with stresses acting in the structure can cause degradation processes of the mechanical properties of the material. Given the importance of the phenomenon, this work has as main objective the realization of hydrogen electrochemical permeation tests in API 5L X60 and API 5L X65 steels under mechanical loading conditions. A device for performing electrochemical permeation tests of hydrogen in the specimens subjected to stress was used for the tests. Thus, it was possible to observe experimentally the influence of stress on the diffusion properties during the experiment. By applying stress on the order of 20% of the yield strength, it was possible to verify the increase of diffusivity of API 5L X60 steel. Furthermore, there was a strong influence of the stress level of permeability, because a large increase of permeability of API 5L X65 steel. The results indicate that the lattice deformation due to imposed mechanical stress has a great influence on the diffusion properties of materials

Recent advances in the API quality program

International Nuclear Information System (INIS)

Gollhofer, F.R.

1991-01-01

The API now has more than 3 years' operating experience in licensing manufacturers under the API Quality Program. The API evaluation procedures, described in this paper, provide consistency in evaluation and should allow full participation of petroleum equipment suppliers in the worldwide market during the 1990's and into the 21st century. The program's flexibility will allow it to cope with significant changes resulting from the planned European Common Market's Global Approach to Certification and Testing scheduled to occur in 1992

USAJOBS Job Opportunity Announcements (JOA) SOAP API

Data.gov (United States)

Office of Personnel Management — The purpose of the SOAP based API is to provide the full Federal Job Opportunity Announcement (JOA) content to the consumer. It is anticipated that this API will be...

Métodos para atrair e repelir a abelha Apis mellifera (L. em cultura de maracujá amarelo (Passiflora edulis flavicarpa flavicarpa Deg. - DOI: 10.4025/actascianimsci.v25i1.2036 Methods to attract and repel Africanize honey bees Apis mellifera, L., to passion fruit (Passiflora edulis flavicarpa flavicarpa Deg. - DOI: 10.4025/actascianimsci.v25i1.2036

Directory of Open Access Journals (Sweden)

Marta Maria Rossi

2003-04-01

Full Text Available Este experimento foi conduzido no Centro Universitário Moura Lacerda, Campus Ribeirão Preto, Estado de São Paulo, e teve como objetivos observar a eficiência dos extratos de capim-limão (Cymbopogon citratus, manjericão (Ocimum basilicum L. e falsa melissa (Lippia alba, como atrativos, e citronela (C. nardus, extratos de orégano, pimenta-do-reino, canela e cravo, como repelentes, que foram comparados a outros atrativos (eugenol e linalol e repelentes (n.octyl.acetato, 2.heptanona e citronellal, obtidos comercialmente, para a A. mellifera. Foram estudados, ainda, os insetos visitantes nas flores do maracujá amarelo (Passiflora edulis f. flavicarpa Deg., além de testar plantas-iscas para essas abelhas. Os produtos testados in vitro e, posteriormente, testados tanto pulverizados quanto em tubos, não foram eficientes para atrair ou repelir a abelha Apis mellifera. Os produtos n.octyl.acetato e citronellal repeliram completamente tanto as abelhas africanizadas quanto as Xylocopa, não devendo ser utilizado em cultivos comerciais. O girassol (Hellianthus annuus e o cosmos (Cosmos sulphureus podem ser utilizados como alternativas para afastar a abelha A. mellifera das flores do maracujá.This experiment was carried out at Centro Universitário Moura Lacerda, Ribeirão Preto, state of São Paulo, Brazil, to study Africanized honey bee (Apis mellifera L. attractives and repellents in vitro, in tubes and on passion fruit flowers (Passiflora edulis flavicarpa flavicarpa Deg.. Visiting insects were studied in flowers and also, bait-plants to Africanized honey bees were tested. The products were not effective in attracting and repelling the honey bee in vitro and in tube tests. The chemicals n.octyl.acetato and citronellal were repellent to honey bees and Xylocopa bees on passion fruit flowers. Sunflower (Hellianthus annuus and cosmos (Cosmos sulphureus flowers can be used to remove Africanized honey bees from passion fruit crops.

Identification of clinical yeasts by Vitek MS system compared with API ID 32 C.

Science.gov (United States)

Durán-Valle, M Teresa; Sanz-Rodríguez, Nuria; Muñoz-Paraíso, Carmen; Almagro-Moltó, María; Gómez-Garcés, José Luis

2014-05-01

We performed a clinical evaluation of the Vitek MS matrix-assisted laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF MS) system with the commercial database version 2.0 for rapid identification of medically important yeasts as compared with the conventional phenotypic method API ID 32 C. We tested 161 clinical isolates, nine isolates from culture collections and five reference strains. In case of discrepant results or no identification with one or both methods, molecular identification techniques were employed. Concordance between both methods was observed with 160/175 isolates (91.42%) and misidentifications by both systems occurred only when taxa were not included in the respective databases, i.e., one isolate of Candida etchellsii was identified as C. globosa by Vitek MS and two isolates of C. orthopsilosis were identified as C. parapsilosis by API ID 32 C. Vitek MS could not identify nine strains (5.14%) and API ID 32 C did not identify 13 (7.42%). Vitek MS was more reliable than API ID 32 C and reduced the time required for the identification of clinical isolates to only a few minutes.

"Ne kreshtshenogo, ne otpetogo..." : [luuletused] / Marina Petrova

Index Scriptorium Estoniae

Petrova, Marina

2001-01-01

Sisu: "Ne kreshtshenogo, ne otpetogo..." ; "Inogo mesta vstretshi v mire net..." ; "Moi put lezhit tsherez Moskvu..." ; "Osvoboditelnaja ossen - ..." ; Pjuhtitskim aistam ; "Vesjolõje svetshi kanona..." ; Vjuga ; Materi Bozhijei Pjuhtitskoi ; "Pustõnja moja, pustõnja..." ; "Odinnadtsat let v mojo serdtse gljadjat kupola..."

Efeitos da seleção para peso pós-desmame sobre medidas corporais e perímetro escrotal de machos Nelore de Sertãozinho (SP Effects of post-weaning weight selection on body measurements and scrotal perimeter in Nellore males of Sertãozinho (SP

Directory of Open Access Journals (Sweden)

Joslaine Noely dos Santos Gonçalves Cyrillo

2000-04-01

Full Text Available O objetivo deste estudo foi avaliar o efeito indireto da seleção para peso pós-desmame sobre medidas corporais e perímetro escrotal de 809 machos Nelore, pertencentes às populações selecionadas (NeS e NeT e controle (NeC, da Estação Experimental de Zootecnia de Sertãozinho. As análises estatísticas foram executadas usando-se modelos de touros, sendo que a fonte de variação aleatória, touro, foi aninhada dentro de rebanho. Os efeitos fixos considerados foram: rebanho, ano de realização da Prova de Ganho de Peso (PGP, idade de vaca em anos e idade do animal em dias como covariável. A mudança genética, obtida como a diferença dos rebanhos selecionados em relação ao rebanho controle, foi 40,2 e 44,3 kg, para peso aos 378 dias (P378, para os rebanhos NeS e NeT, respectivamente. As mudanças para as demais características, na mesma ordem, foram 4,5 e 4,5 cm para altura na garupa (ATPF; 6,2 e 7,0 cm para perímetro torácico (PTOR; 5,8 e 6,3 cm para comprimento do corpo (COM; 2,9 e 2,0 cm para comprimento do dorso (DOR; 1,7 e 2,4 cm para comprimento da garupa, (GAR; 1,0 e 1,3 cm para distância de ísquios (ISQ; 1,8 e 2,6 cm para distância de íleos (ILEO; e 1,3 e 2,2 cm para perímetro escrotal (PE. Os resultados deste estudo mostraram que a seleção direta para peso pós-desmame promoveu respostas positivas correlacionadas nas dimensões de regiões do corpo de machos Nelore.The objective of this study was to evaluate the indirect effects of selection for post-weaning weight on body measures and scrotal perimeter of 809 Nellore males from selected herds (NeS and NeT and control herd (NeC, of the Estação Experimental de Zootecnia de Sertãozinho. The statistical analyses were performed by using a sire mixed model where the random source of variation, sires, was nested within herds. The fixed effects were herds, year of performance test (PGP, age of cow and age of the animal as a covariate. The average genetic change for

Inversão da sacarose utilizando ácido cítrico e suco de limão para preparo de dieta energética de Apis mellifera Linnaeus, 1758 Inversion of the sucrose using citric acid and lemon juice for preparing energetic diet of Apis mellifera Linnaeus, 1758

Directory of Open Access Journals (Sweden)

Deodoro Magno Brighenti

2011-04-01

Full Text Available Em época de escassez de néctar, pode-se fornecer ao enxame uma suplementação alimentar utilizando "açúcar invertido" que é obtido pela hidrólise da sacarose em meio ácido por aquecimento, formando uma mistura de glicose e frutose. O ácido normalmente utilizado em tal reação é o ácido cítrico, no entanto, diante da dificuldade de pequenos produtores apícolas em obterem tal produto comercialmente, uma alternativa seria substituí-lo pela utilização de suco de limões. Sendo assim, o objetivo deste trabalho foi quantificar a inversão da sacarose em dietas para operárias de Apis mellifera, empregando-se o ácido cítrico e sucos de limões. Prepararam-se 21 soluções aquosas de açúcar cristal na proporção de 100 g/100 mL, colocando-se em cada uma 1,0; 2,0; 3,0; 5,0; 10,0; 15,0 ou 20,0 mL de suco dos limões Galego [Citrus aurantifolia (C. Swingle], Tahiti [Citrus latifolia Tanaka] ou Cravo [Citrus limonia (L. Osbeck]. Além dessas, outras seis soluções aquosas de açúcar na mesma proporção foram preparadas adicionando-se 0,1; 0,16; 0,3; 0,5 e 0,7 g de ácido cítrico e uma para testemunha. Quantificou-se a inversão pelo método de Somogyi-Nelson. Para o limão Cravo foi encontrada a menor porcentagem de inversão. Em relação a adição de ácido cítrico, constatou-se que ao colocar 0,1 g, a inversão foi estimada em 12,2% enquanto que, com a adição de 0,16 g, a inversão seria de 18,8%. A quantidade máxima de ácido cítrico a ser adicionada foi estimada em 0,18 g adotando como critério o pH médio de 3,3 dos méis de abelhas africanizadas. Para os sucos dos limões Galego, Tahiti e Cravo, quando utilizados como substitutos do ácido cítrico, estimou-se a quantidade máxima a ser adicionada sendo igual a 2,1; 3,6 e 5,3 mL, respectivamente, para cada 100 g de açúcar em 100 mL de água, para o pH fixado em 3,3. Considerando-se a inversão e o pH, o suco do limão Tahiti forneceu melhores resultados.In times of

Índices de prevalencia del ácaro Varroa destructor (Acari: Varroidae en cuadros de cría nuevos o previamente utilizados por Apis mellifera (Hymenoptera: Apidae Infestation levels of the mite Varroa destructor (Acari: Varroidae in new and old honeybee brood combs of Apis mellifera (Hymenoptera: Apidae

Directory of Open Access Journals (Sweden)

Jorge, A. Marcangeli

2007-07-01

Full Text Available El objetivo de esta investigación fue comparar los niveles de infestación de Varroa destructor (Anderson & Trueman en panales de cría nuevos y viejos, en colonias de la abeja criolla (híbrido de Apis mellifera mellifera (Linnaeus y Apis mellifera ligustica Spinola. El trabajo se llevó a cabo en un apiario ubicado en Coronel Vidal, provincia de Buenos Aires, durante la primavera del año 2005. Se trabajó sobre 20 colmenas tipo Langstroth, de un híbrido de Apis mellifera (Linnaeus infestadas naturalmente por el ácaro Varroa destructor, y seleccionadas al azar. En cada una de ellas se escogió un panal de 2 años (viejo que se colocó en el centro del nido de cría, junto con un panal recientemente labrado por las abejas (nuevo. Luego de que ambos cuadros fueran operculados, se los extrajo y se llevaron al laboratorio para su posterior análisis. Cada una de las celdas de cría se desoperculó e inspeccionó en busca de ácaros, registrándose el número de hembras de ácaros que habían ingresado para su reproducción, se calculó el nivel de infestación como el cociente entre el número de celdas infestadas por ácaros y el número total de celdas inspeccionadas. Los resultados mostraron que los panales viejos presentaron niveles de infestación significativamente superiores a los registrados en panales nuevos (13,52% ± 3,35 y 6,18% ± 2,12 respectivamente; t = 10,62; p = 1,9 E-9; g. l.= 19. El mismo patrón fue observado en el número promedio de ácaros por panal (443,3 ± 70,54 y 217,85 ± 51,76 para panales viejos y nuevos respectivamente; t = 23,87; p = 1,24 E-15; g. l.= 19. Los ácaros presentan una marcada preferencia por los panales viejos. Esta selección estaría guiada por olores propios de las celdas, que actuarían como atrayentes. Además, posiblemente enmascaran su presencia de esta manera y evitan así ser detectados y eliminados por las abejas nodrizas mediante los comportamientos higiénicos.The aim of this work was to

Safe "cloudification" of large images through picker APIs.

Science.gov (United States)

Bremer, Erich; Kurc, Tahsin; Gao, Yi; Saltz, Joel; Almeida, Jonas S

2016-01-01

The "Box model" allows users with no particular training in informatics, or access to specialized infrastructure, operate generic cloud computing resources through a temporary URI dereferencing mechanism known as "drop-file-picker API" ("picker API" for sort). This application programming interface (API) was popularized in the web app development community by DropBox, and is now a consumer-facing feature of all major cloud computing platforms such as Box.com, Google Drive and Amazon S3. This reports describes a prototype web service application that uses picker APIs to expose a new, "cloudified", API tailored for image analysis, without compromising the private governance of the data exposed. In order to better understand this cross-platform cloud computing landscape, we first measured the time for both transfer and traversing of large image files generated by whole slide imaging (WSI) in Digital Pathology. The verification that there is extensive interconnectivity between cloud resources let to the development of a prototype software application that exposes an image-traversing REST API to image files stored in any of the consumer-facing "boxes". In summary, an image file can be upload/synchronized into a any cloud resource with a file picker API and the prototype service described here will expose an HTTP REST API that remains within the safety of the user's own governance. The open source prototype is publicly available at sbu-bmi.github.io/imagebox. Availability The accompanying prototype application is made publicly available, fully functional, with open source, at http://sbu-bmi.github.io/imagebox://sbu-bmi.github.io/imagebox. An illustrative webcasted use of this Web App is included with the project codebase at https://github.com/SBU-BMI/imageboxs://github.com/SBU-BMI/imagebox.

BEE VENOM TRAP DESIGN OF APIS MELLIFERA L. AND APIS CERANA F. HONEY BEES

OpenAIRE

Budiaman

2015-01-01

The nectar and pollen of flowers which are abundance have not been taken into account for any purpose in forest, agriculture and plantation area. Honey bees such as Apis mellifera L. and Apis cerana F. had known as biological pollinators which could converted the flower components to be high economy products in the forms of honey, royal jelly, propolis, bee wax and bee venom. Among the products, bee venom has the best selling value, but the method of it???s optimal production has not been ext...

Google Maps API za izradu interaktivne karte sa ciljem utvrđivanja lokacije : Google Maps API as a development tool for implementing a dynamic map for the purpose of locating points of interest

Directory of Open Access Journals (Sweden)

Amir Hajdar

2014-12-01

Full Text Available Google Maps API je programibilno korisničko okruženje razvijeno od strane Google-a kako bi se omogućio razvoj softverskih rješenja koji zahtijevaju funkcionalnosti manipulacije kartama. Koristeći internet tehnologije, današnje karte se razvijaju kako bi bile interaktivne (dinamičke, a ne samo statičke kako je to bilo do sada. U radu je opisana ideja zasnovana na Google Maps API, te su postavljeni okviri o tome šta je sve potrebno da se karta implementira. Kao i sve ostale tehnologije, i ova tehnologija ima svoje nedostatke koji su opisani u radu. Implementiranjem testnih rezultata zaključeno je da proizvođači nisu standardizovali uređaje za zapis položajnih podataka u snimak po EXIF standardu. Dakle, važno je znati o kojem se proizvođaču i uređaju radi, te sa testnim snimkom tog uređaja testirati softver, a prije svega PHP instalaciju, kako bi ustanovili da li je moguće preuzeti podatke o lokaciji iz snimka. Također je kreirana internet stranica na kojoj korisnik može testirati snimke koji imaju položajne podatke. : Google Maps API is an application programming interface developed by Google in order to aid software developers to easier develop mapping software. Using internet technologies, todays maps are created to be dynamic, and not static as they used to be. This paper defines the concept of using Google Maps API, and explains the steps needed to start developing a mapping software. Like any other technologies, this technology also has weakneses which are described in the paper. Through testing, it was concluded that manufacturers are not yet fully complied with EXIF standard. So, it is absolutely necessary to test the device and PHP installation before we can be sure that the data from the photo can be read. Web page has been created. At this web page user is able to test his/her own photographs with location embedded data and the link is given in the paper.

Desarrollo de aplicaciones para Windows Phone

OpenAIRE

Castellanos de la Torre, Francisco José

2013-01-01

Desarrollar una aplicación para dispositivos móviles no es una tarea sencilla, ya que precisamos no solo tener conocimientos de programación, sino que también tenemos que familiarizarnos muy bien con el entorno de desarrollo y el sistema operativo para el cual pretendemos crear la aplicación. Esto consiste en conocer en profundidad tanto las características técnicas de los dispositivos como las distintas APIs que tenemos a nuestra disposición. Hemos elegido Windows Phone 7.5 porque ha sido...

Diffusion processes in the relaxed cross sections for the reaction 107109Ag+20Ne

International Nuclear Information System (INIS)

Babinet, R.; Moretto, L.G.; Galin, J.; Jared, R.; Moulton, J.; Thompson, S.G.

1976-01-01

The fragments emitted in the reaction 107 109 Ag+ 20 Ne at 175 and 252 MeV bombarding energy have been identified in charge up to Z=32. Kinetic energy distributions, cross sections and angular distributions have been measured for each Z. The kinetic energy spectra show the two usual components: the quasielastic component and the relaxed component. The Z-distribution of the latter is fairly flat, slowly decreasing up to Z approximately 15 and then rising again up to Z=30. The variations in the Z-distribution are more pronounced at the lower bombarding energy. The angular distributions associated with the relaxed component are forward peaked for Z-values close to that of the projectile and behave like 1/sintheta for larger Z-values. The forward peaking is very substantial for Z 10 the forward peaking in excess of 1/sintheta disappears around Z=15. These features are interpreted in terms of a diffusion process along the asymmetry coordinate of a short-lived intermediate complex. (Auth.)

Automated Ply Inspection (API) for AFP, Phase I

Data.gov (United States)

National Aeronautics and Space Administration — The Automated Ply Inspection (API) system autonomously inspects layups created by high speed automated fiber placement (AFP) machines. API comprises a high accuracy...

API de Servicios para Dispositivos Móviles

Directory of Open Access Journals (Sweden)

Denys Buedo Hidalgo

2010-07-01

Full Text Available Durante el transcurso de los últimos años los servicios de mensajería inalámbrica (SMS, MMS y WAP Push han tenido un gran impacto en el mercado internacional. Haciendo uso de estos, se pueden generar una amplia variedad de servicios, permitiendo a las diferentes empresas de este sector obtener ganancias millonarias. En la actualidad existen varios protocolos de comunicación que permiten la transferencia de estos mensajes a los SMS Centers (SMSC y MMS Centers (MMSC, en lo adelante Centros de Mensajería Inalámbrica. Debido a la gran variedad de protocolos, así como las soluciones existentes en el mercado, han surgido ideas de cómo estandarizar dicha comunicación independientemente de cual sea el protocolo que se utilice para la transferencia de la información. En tal sentido surge en el año 2004 una especificación liderada principalmente por Nokia y Sun Microsystems conocida como SAMS. El presente trabajo trata sobre una implementación de dicha especificación, así como el desarrollo de los drivers para los protocolos PDU (Protocol Data Unit y SMPP (Short Message Peer to Peer v3.3 que permitan la transferencia de mensajes SMS, MMS y WAP Push entre las aplicaciones desarrolladas por las Empresas Proveedoras de Servicios y los Centros de Mensajería Inalámbrica. Se presenta además el desarrollo de elementos que no forman parte de la especificación pero que a su vez enriquecen la solución, dándole a la misma un mayor nivel de usabilidad.

An example of how to handle amorphous fractions in API during early pharmaceutical development: SAR114137--a successful approach.

Science.gov (United States)

Petzoldt, Christine; Bley, Oliver; Byard, Stephen J; Andert, Doris; Baumgartner, Bruno; Nagel, Norbert; Tappertzhofen, Christoph; Feth, Martin Philipp

2014-04-01

The so-called pharmaceutical solid chain, which encompasses drug substance micronisation to the final tablet production, at pilot plant scale is presented as a case study for a novel, highly potent, pharmaceutical compound: SAR114137. Various solid-state analytical methods, such as solid-state Nuclear Magnetic Resonance (ssNMR), Differential Scanning Calorimetry (DSC), Dynamic Water Vapour Sorption Gravimetry (DWVSG), hot-stage Raman spectroscopy and X-ray Powder Diffraction (XRPD) were applied and evaluated to characterise and quantify amorphous content during the course of the physical treatment of crystalline active pharmaceutical ingredient (API). DSC was successfully used to monitor the changes in amorphous content during micronisation of the API, as well as during stability studies. (19)F solid-state NMR was found to be the method of choice for the detection and quantification of low levels of amorphous API, even in the final drug product (DP), since compaction during tablet manufacture was identified as a further source for the formation of amorphous API. The application of different jet milling techniques was a critical factor with respect to amorphous content formation. In the present case, the change from spiral jet milling to loop jet milling led to a decrease in amorphous API content from 20-30 w/w% to nearly 0 w/w% respectively. The use of loop jet milling also improved the processability of the API. Stability investigations on both the milled API and the DP showed a marked tendency for recrystallisation of the amorphous API content on exposure to elevated levels of relative humidity. No significant impact of amorphous API on either the chemical stability or the dissolution rate of the API in drug formulation was observed. Therefore, the presence of amorphous content in the oral formulation was of no consequence for the clinical trial phases I and II. Copyright © 2013 Elsevier B.V. All rights reserved.

Analysing PKCS#11 Key Management APIs with Unbounded Fresh Data

Science.gov (United States)

Fröschle, Sibylle; Steel, Graham

We extend Delaune, Kremer and Steel’s framework for analysis of PKCS#11-based APIs from bounded to unbounded fresh data. We achieve this by: formally defining the notion of an attribute policy; showing that a well-designed API should have a certain class of policy we call complete; showing that APIs with complete policies may be safely abstracted to APIs where the attributes are fixed; and proving that these static APIs can be analysed in a small bounded model such that security properties will hold for the unbounded case. We automate analysis in our framework using the SAT-based security protocol model checker SATMC. We show that a symmetric key management subset of the Eracom PKCS#11 API, used in their ProtectServer product, preserves the secrecy of sensitive keys for unbounded numbers of fresh keys and handles, i.e. pointers to keys. We also show that this API is not robust: if an encryption key is lost to the intruder, SATMC finds an attack whereby all the keys may be compromised.

Compositional mining of multiple object API protocols through state abstraction.

Science.gov (United States)

Dai, Ziying; Mao, Xiaoguang; Lei, Yan; Qi, Yuhua; Wang, Rui; Gu, Bin

2013-01-01

API protocols specify correct sequences of method invocations. Despite their usefulness, API protocols are often unavailable in practice because writing them is cumbersome and error prone. Multiple object API protocols are more expressive than single object API protocols. However, the huge number of objects of typical object-oriented programs poses a major challenge to the automatic mining of multiple object API protocols: besides maintaining scalability, it is important to capture various object interactions. Current approaches utilize various heuristics to focus on small sets of methods. In this paper, we present a general, scalable, multiple object API protocols mining approach that can capture all object interactions. Our approach uses abstract field values to label object states during the mining process. We first mine single object typestates as finite state automata whose transitions are annotated with states of interacting objects before and after the execution of the corresponding method and then construct multiple object API protocols by composing these annotated single object typestates. We implement our approach for Java and evaluate it through a series of experiments.

Comparison of API 510 pressure vessels inspection planning with API 581 risk-based inspection planning approaches

International Nuclear Information System (INIS)

Shishesaz, Mohammad Reza; Nazarnezhad Bajestani, Mohammad; Hashemi, Seyed Javad; Shekari, Elahe

2013-01-01

To ensure mechanical integrity, all pressure vessels shall be inspected at the intervals provided in inspection codes or based on a risk-based inspection (RBI) assessment. The RBI assessment may allow previously established inspection intervals to be extended. This paper describes the methodology, analysis and results of two RBI studies conducted on 293 pressure vessel components in two crude oil distillation units. Based on API RBI methodology in API 581 (2008), risk target concept was used for determining inspection dates. It was shown that when thinning is the major active damage, the RBI recommended intervals are as long as twice the API 510 intervals. This paper summarizes that, as a fundamental step in the risk calculation, RBI has a more defined methodology for evaluating equipment for multiple damage mechanisms and a more defined approach to specify the use of other inspection technologies beyond the traditional visual, ultrasonic, and radiography tests. -- Highlights: • RBI calculated inspection intervals are as long as twice of API 510 inspection code. • Two case studies verified the advantage of RBI in inspection planning. • RBI is a more reliable methodology when evaluating multiple damage mechanisms. • Damage factor calculations can be used for determining RSFa value in FFS assessments

Thermodynamic phase behavior of API/polymer solid dispersions.

Science.gov (United States)

Prudic, Anke; Ji, Yuanhui; Sadowski, Gabriele

2014-07-07

To improve the bioavailability of poorly soluble active pharmaceutical ingredients (APIs), these materials are often integrated into a polymer matrix that acts as a carrier. The resulting mixture is called a solid dispersion. In this work, the phase behaviors of solid dispersions were investigated as a function of the API as well as of the type and molecular weight of the carrier polymer. Specifically, the solubility of artemisinin and indomethacin was measured in different poly(ethylene glycol)s (PEG 400, PEG 6000, and PEG 35000). The measured solubility data and the solubility of sulfonamides in poly(vinylpyrrolidone) (PVP) K10 and PEG 35000 were modeled using the perturbed-chain statistical associating fluid theory (PC-SAFT). The results show that PC-SAFT predictions are in a good accordance with the experimental data, and PC-SAFT can be used to predict the whole phase diagram of an API/polymer solid dispersion as a function of the kind of API and polymer and of the polymer's molecular weight. This remarkably simplifies the screening process for suitable API/polymer combinations.

A knowledge discovery object model API for Java

Directory of Open Access Journals (Sweden)

Jones Steven JM

2003-10-01

Full Text Available Abstract Background Biological data resources have become heterogeneous and derive from multiple sources. This introduces challenges in the management and utilization of this data in software development. Although efforts are underway to create a standard format for the transmission and storage of biological data, this objective has yet to be fully realized. Results This work describes an application programming interface (API that provides a framework for developing an effective biological knowledge ontology for Java-based software projects. The API provides a robust framework for the data acquisition and management needs of an ontology implementation. In addition, the API contains classes to assist in creating GUIs to represent this data visually. Conclusions The Knowledge Discovery Object Model (KDOM API is particularly useful for medium to large applications, or for a number of smaller software projects with common characteristics or objectives. KDOM can be coupled effectively with other biologically relevant APIs and classes. Source code, libraries, documentation and examples are available at http://www.bcgsc.ca/bioinfo/software.

Mass spectrometer determinations of solar wind He, Ne, and Ar and radiation belt He

International Nuclear Information System (INIS)

Warasila, R.L.

1976-01-01

A unique mass spectrometer system was built and used to measure He, Ne, and Ar abundances and isotopic ratios in various samples of spacecraft that have been exposed to the space environment. The Apollo 12 mission brought back sections of the Surveyor 3 vehicle suitable for mass spectrometric studies of implanted solar wind and solar cosmic ray particles. Using the mass spectrometer, a 4 He flux of 6-8 x 10 6 ions/cm 2 --sec was measured, and in addition 4 He/ 3 He = 2700 +- 50; 4 He/ 20 Ne = 410 + 30; 20 Ne/ 22 Ne = 13.5 +- 0.2; 20 Ne/ 36 Ar = 24.5 +- 2.5; and 36 Ar/ 38 Ar = 5.41 +- 0.20 isotopic abundances were measured. An upper limit for the flux of SCR 3 He in the 10-20 MeV/nucleon range was also determined, for the thirty-one month exposure period. In the radiation belt environment, 3 He was found in the aluminum antenna housing from the recovered second stage of a pre-Apollo Saturn test flight launched January 28, 1964 and returned to earth on April 28, 1966. The amount of 3 He found was about 6 x 10 -10 cc(STP)/cm 2 with a 4 He/ 3 He ratio of 145 or less. The 3 He was shown to come from the lower radiation belt as all other sources of 3 He were orders of magnitude lower than the observed value

Validation of the Parlay API through prototyping

NARCIS (Netherlands)

Hellenthal, J.W.; Planken, F.J.M.; Wegdam, M.

2001-01-01

The desire within the telecommunications world for new and faster business growth has been a major drive towards the development of open network API. Over the past 7 years several (semi) standardization groups have announced work on network API, including TINA-C, JAIN, IEEE P1520, INforum, 3GPP,

Comportamiento a la Corrosión del Acero API X70 Soldado por el Proceso de Doble Arco Sumergido Inmerso en Diferentes Medios Corrosivos

OpenAIRE

Montes, Omar Francisco; Garcés, Rocío Saldaña; Reyes, Felipe A. Reyes; Robledo, Patricia del Carmen Zambrano; López, Francisco H. Estupiñán; Calderón, Facundo Almeraya

2016-01-01

Resumen Los aceros API X70 son aplicados en fabricación y construcción de tuberías para el transporte de hidrocarburos, sin embargo, a un lapso de tiempo se degradan debido al medio ambiente al cual están expuestos; influyendo en la velocidad y tipo de corrosión sobre las superficies del metal base (MB), zona afectada por el calor (ZAC) y zona de fusión (ZF). A fin de conocer y evaluar la susceptibilidad a la corrosión en uniones del acero API X70 sometido a diferentes medios corrosivos, vari...

A Ruby API to query the Ensembl database for genomic features.

Science.gov (United States)

Strozzi, Francesco; Aerts, Jan

2011-04-01

The Ensembl database makes genomic features available via its Genome Browser. It is also possible to access the underlying data through a Perl API for advanced querying. We have developed a full-featured Ruby API to the Ensembl databases, providing the same functionality as the Perl interface with additional features. A single Ruby API is used to access different releases of the Ensembl databases and is also able to query multi-species databases. Most functionality of the API is provided using the ActiveRecord pattern. The library depends on introspection to make it release independent. The API is available through the Rubygem system and can be installed with the command gem install ruby-ensembl-api.

A framework for API solubility modelling

DEFF Research Database (Denmark)

Conte, Elisa; Gani, Rafiqul; Crafts, Peter

. In addition, most of the models are not predictive and requires experimental data for the calculation of the needed parameters. This work aims at developing an efficient framework for the solubility modelling of Active Pharmaceutical Ingredients (API) in water and organic solvents. With this framework......-SAFT) are used for solubility calculations when the needed interaction parameters or experimental data are available. The CI-UNIFAC is instead used when the previous models lack interaction parameters or when solubility data are not available. A new GC+ model for APIs solvent selection based...... on the hydrophobicity, hydrophilicity and polarity information of the API and solvent is also developed, for performing fast solvent selection and screening. Eventually, all the previous developments are integrated in a framework for their efficient and integrated use. Two case studies are presented: the first...

Infections with the Sexually Transmitted Pathogen Nosema apis Trigger an Immune Response in the Seminal Fluid of Honey Bees (Apis mellifera).

Science.gov (United States)

Grassl, Julia; Peng, Yan; Baer-Imhoof, Barbara; Welch, Mat; Millar, A Harvey; Baer, Boris

2017-01-06

Honey bee (Apis mellifera) males are highly susceptible to infections with the sexually transmitted fungal pathogen Nosema apis. However, they are able to suppress this parasite in the ejaculate using immune molecules in the seminal fluid. We predicted that males respond to infections by altering the seminal fluid proteome to minimize the risk to sexually transmit the parasite to the queen and her colony. We used iTRAQ isotopic labeling to compare seminal fluid proteins from infected and noninfected males and found that N. apis infections resulted in significant abundance changes in 111 of the 260 seminal fluid proteins quantitated. The largest group of proteins with significantly changed abundances consisted of 15 proteins with well-known immune-related functions, which included two significantly more abundant chitinases in the seminal fluid of infected males. Chitinases were previously hypothesized to be involved in honey bee antifungal activity against N. apis. Here we show that infection with N. apis triggers a highly specific immune response in the seminal fluid of honey bee males.

Study of the 21Ne Nuclear Structure by capture of thermal neutrons in natural neon

International Nuclear Information System (INIS)

Stopa, C.R.S.

1979-01-01

Energy levels of 21 Ne up to 6.76 MeV are studied by measuring the thermal neutron capture gama rays from natural neon. A Ge(Li) detector is used. Energies and intensities are measured relative to calibration lines of nitrogen. The Q-value and the cross section of the reaction 20 Ne(n,γ) 21 Ne are calculated. The proposed level scheme is discussed in terms of the Nilsson model, considering the coupling of one particle to the 20 Ne core. Coriolis coupling is taken into account for the three positive parity bands, K sup(π)=3/2 + , 1/2 + and 5/2 + . Measurements are made using the research reactor of the Instituto de Energia Atomica [pt

Unified Medical Language System Terminology Services (UTS) API

Data.gov (United States)

U.S. Department of Health & Human Services — The UTS API is intended for application developers to perform Web service calls and retrieve UMLS data within their own applications. The UTS API provides the...

CALIBRATION, OPTIMIZATION, AND SENSITIVITY AND UNCERTAINTY ALGORITHMS APPLICATION PROGRAMMING INTERFACE (COSU-API)

Science.gov (United States)

The Application Programming Interface (API) for Uncertainty Analysis, Sensitivity Analysis, and Parameter Estimation (UA/SA/PE API) tool development, here fore referred to as the Calibration, Optimization, and Sensitivity and Uncertainty Algorithms API (COSU-API), was initially d...

The JANA calibrations and conditions database API

International Nuclear Information System (INIS)

Lawrence, David

2010-01-01

Calibrations and conditions databases can be accessed from within the JANA Event Processing framework through the API defined in its JCalibration base class. The API is designed to support everything from databases, to web services to flat files for the backend. A Web Service backend using the gSOAP toolkit has been implemented which is particularly interesting since it addresses many modern cybersecurity issues including support for SSL. The API allows constants to be retrieved through a single line of C++ code with most of the context, including the transport mechanism, being implied by the run currently being analyzed and the environment relieving developers from implementing such details.

The JANA calibrations and conditions database API

Energy Technology Data Exchange (ETDEWEB)

Lawrence, David, E-mail: davidl@jlab.or [12000 Jefferson Ave., Suite 8, Newport News, VA 23601 (United States)

2010-04-01

Calibrations and conditions databases can be accessed from within the JANA Event Processing framework through the API defined in its JCalibration base class. The API is designed to support everything from databases, to web services to flat files for the backend. A Web Service backend using the gSOAP toolkit has been implemented which is particularly interesting since it addresses many modern cybersecurity issues including support for SSL. The API allows constants to be retrieved through a single line of C++ code with most of the context, including the transport mechanism, being implied by the run currently being analyzed and the environment relieving developers from implementing such details.

Associated particle imaging (API)

International Nuclear Information System (INIS)

1998-05-01

Associated Particle Imaging (API) is an active neutron probe technique that provides a 3-D image with elemental composition of the material under interrogation, and so occupies a unique niche in the interrogation of unknown objects. The highly penetrating nature of neutrons enables API to provide detailed information about targets of interest that are hidden from view. Due to the isotropic nature of the induced reactions, radiation detectors can be set on the same side of the object as the neutron source, so that the object can be interrogated from a single side. At the heat of the system is a small generator that produces a continuous, monoenergetic flux of neutrons. By measuring the trajectory of coincident alpha particles that are produced as part of the process, the trajectory of the neutron can be inferred. Interactions between a neutron and the material in its path often produce a gamma ray whose energy is characteristic of that material. When the gamma ray is detected, its energy is measured and combined with the trajectory information to produce a 3-D image of the composition of the object being interrogated. During the course of API development, a number of improvements have been made. A new, more rugged sealed Tube Neutron Generator (STNG) has been designed and fabricated that is less susceptible to radiation damage and better able to withstand the rigors of fielding than earlier designs. A specialized high-voltage power supply for the STNG has also been designed and built. A complete package of software has been written for the tasks of system calibration, diagnostics and data acquisition and analysis. A portable system has been built and field tested, proving that API can be taken out of the lab and into real-world situations, and that its performance in the field is equal to that in the lab

Uncovering the immune responses of Apis mellifera ligustica larval gut to Ascosphaera apis infection utilizing transcriptome sequencing.

Science.gov (United States)

Chen, Dafu; Guo, Rui; Xu, Xijian; Xiong, Cuiling; Liang, Qin; Zheng, Yanzhen; Luo, Qun; Zhang, Zhaonan; Huang, Zhijian; Kumar, Dhiraj; Xi, Weijun; Zou, Xuan; Liu, Min

2017-07-20

Honeybees are susceptible to a variety of diseases, including chalkbrood, which is capable of causing huge losses of both the number of bees and colony productivity. This research is designed to characterize the transcriptome profiles of Ascosphaera apis-treated and un-treated larval guts of Apis mellifera ligustica in an attempt to unravel the molecular mechanism underlying the immune responses of western honeybee larval guts to mycosis. In this study, 24, 296 and 2157 genes were observed to be differentially expressed in A. apis-treated Apis mellifera (4-, 5- and 6-day-old) compared with un-treated larval guts. Moreover, the expression patterns of differentially expressed genes (DEGs) were examined via trend analysis, and subsequently, gene ontology analysis and KEGG pathway enrichment analysis were conducted for DEGs involved in up- and down-regulated profiles. Immunity-related pathways were selected for further analysis, and our results demonstrated that a total of 13 and 50 DEGs were annotated in the humoral immune-related and cellular immune-related pathways, respectively. Additionally, we observed that many DEGs up-regulated in treated guts were part of cellular immune pathways, such as the lysosome, ubiquitin mediated proteolysis, and insect hormone biosynthesis pathways and were induced by A. apis invasion. However, more down-regulated DEGs were restrained. Surprisingly, a majority of DEGs within the Toll-like receptor signaling pathway, and the MAPK signaling pathway were up-regulated in treated guts, while all but two genes involved in the NF-κB signaling pathway were down-regulated, which suggested that most genes involved in humoral immune-related pathways were activated in response to the invasive fungal pathogen. This study's findings provide valuable information regarding the investigation of the molecular mechanism of immunity defenses of A. m. ligustica larval guts to infection with A. apis. Furthermore, these studies lay the groundwork for

Letter of intent for KM3NeT 2.0

Science.gov (United States)

Adrián-Martínez, S.; Ageron, M.; Aharonian, F.; Aiello, S.; Albert, A.; Ameli, F.; Anassontzis, E.; Andre, M.; Androulakis, G.; Anghinolfi, M.; Anton, G.; Ardid, M.; Avgitas, T.; Barbarino, G.; Barbarito, E.; Baret, B.; Barrios-Martí, J.; Belhorma, B.; Belias, A.; Berbee, E.; van den Berg, A.; Bertin, V.; Beurthey, S.; van Beveren, V.; Beverini, N.; Biagi, S.; Biagioni, A.; Billault, M.; Bondì, M.; Bormuth, R.; Bouhadef, B.; Bourlis, G.; Bourret, S.; Boutonnet, C.; Bouwhuis, M.; Bozza, C.; Bruijn, R.; Brunner, J.; Buis, E.; Busto, J.; Cacopardo, G.; Caillat, L.; Calamai, M.; Calvo, D.; Capone, A.; Caramete, L.; Cecchini, S.; Celli, S.; Champion, C.; Cherkaoui El Moursli, R.; Cherubini, S.; Chiarusi, T.; Circella, M.; Classen, L.; Cocimano, R.; Coelho, J. A. B.; Coleiro, A.; Colonges, S.; Coniglione, R.; Cordelli, M.; Cosquer, A.; Coyle, P.; Creusot, A.; Cuttone, G.; D'Amico, A.; De Bonis, G.; De Rosa, G.; De Sio, C.; Di Capua, F.; Di Palma, I.; Díaz García, A. F.; Distefano, C.; Donzaud, C.; Dornic, D.; Dorosti-Hasankiadeh, Q.; Drakopoulou, E.; Drouhin, D.; Drury, L.; Durocher, M.; Eberl, T.; Eichie, S.; van Eijk, D.; El Bojaddaini, I.; El Khayati, N.; Elsaesser, D.; Enzenhöfer, A.; Fassi, F.; Favali, P.; Fermani, P.; Ferrara, G.; Filippidis, C.; Frascadore, G.; Fusco, L. A.; Gal, T.; Galatà, S.; Garufi, F.; Gay, P.; Gebyehu, M.; Giordano, V.; Gizani, N.; Gracia, R.; Graf, K.; Grégoire, T.; Grella, G.; Habel, R.; Hallmann, S.; van Haren, H.; Harissopulos, S.; Heid, T.; Heijboer, A.; Heine, E.; Henry, S.; Hernández-Rey, J. J.; Hevinga, M.; Hofestädt, J.; Hugon, C. M. F.; Illuminati, G.; James, C. W.; Jansweijer, P.; Jongen, M.; de Jong, M.; Kadler, M.; Kalekin, O.; Kappes, A.; Katz, U. F.; Keller, P.; Kieft, G.; Kießling, D.; Koffeman, E. N.; Kooijman, P.; Kouchner, A.; Kulikovskiy, V.; Lahmann, R.; Lamare, P.; Leisos, A.; Leonora, E.; Clark, M. Lindsey; Liolios, A.; Llorens Alvarez, C. D.; Lo Presti, D.; Löhner, H.; Lonardo, A.; Lotze, M.; Loucatos, S.; Maccioni, E.; Mannheim, K.; Margiotta, A.; Marinelli, A.; Mariş, O.; Markou, C.; Martínez-Mora, J. A.; Martini, A.; Mele, R.; Melis, K. W.; Michael, T.; Migliozzi, P.; Migneco, E.; Mijakowski, P.; Miraglia, A.; Mollo, C. M.; Mongelli, M.; Morganti, M.; Moussa, A.; Musico, P.; Musumeci, M.; Navas, S.; Nicolau, C. A.; Olcina, I.; Olivetto, C.; Orlando, A.; Papaikonomou, A.; Papaleo, R.; Păvălaş, G. E.; Peek, H.; Pellegrino, C.; Perrina, C.; Pfutzner, M.; Piattelli, P.; Pikounis, K.; Poma, G. E.; Popa, V.; Pradier, T.; Pratolongo, F.; Pühlhofer, G.; Pulvirenti, S.; Quinn, L.; Racca, C.; Raffaelli, F.; Randazzo, N.; Rapidis, P.; Razis, P.; Real, D.; Resvanis, L.; Reubelt, J.; Riccobene, G.; Rossi, C.; Rovelli, A.; Saldaña, M.; Salvadori, I.; Samtleben, D. F. E.; Sánchez García, A.; Sánchez Losa, A.; Sanguineti, M.; Santangelo, A.; Santonocito, D.; Sapienza, P.; Schimmel, F.; Schmelling, J.; Sciacca, V.; Sedita, M.; Seitz, T.; Sgura, I.; Simeone, F.; Siotis, I.; Sipala, V.; Spisso, B.; Spurio, M.; Stavropoulos, G.; Steijger, J.; Stellacci, S. M.; Stransky, D.; Taiuti, M.; Tayalati, Y.; Tézier, D.; Theraube, S.; Thompson, L.; Timmer, P.; Tönnis, C.; Trasatti, L.; Trovato, A.; Tsirigotis, A.; Tzamarias, S.; Tzamariudaki, E.; Vallage, B.; Van Elewyck, V.; Vermeulen, J.; Vicini, P.; Viola, S.; Vivolo, D.; Volkert, M.; Voulgaris, G.; Wiggers, L.; Wilms, J.; de Wolf, E.; Zachariadou, K.; Zornoza, J. D.; Zúñiga, J.

2016-08-01

The main objectives of the KM3NeT Collaboration are (i) the discovery and subsequent observation of high-energy neutrino sources in the Universe and (ii) the determination of the mass hierarchy of neutrinos. These objectives are strongly motivated by two recent important discoveries, namely: (1) the high-energy astrophysical neutrino signal reported by IceCube and (2) the sizable contribution of electron neutrinos to the third neutrino mass eigenstate as reported by Daya Bay, Reno and others. To meet these objectives, the KM3NeT Collaboration plans to build a new Research Infrastructure consisting of a network of deep-sea neutrino telescopes in the Mediterranean Sea. A phased and distributed implementation is pursued which maximises the access to regional funds, the availability of human resources and the synergistic opportunities for the Earth and sea sciences community. Three suitable deep-sea sites are selected, namely off-shore Toulon (France), Capo Passero (Sicily, Italy) and Pylos (Peloponnese, Greece). The infrastructure will consist of three so-called building blocks. A building block comprises 115 strings, each string comprises 18 optical modules and each optical module comprises 31 photo-multiplier tubes. Each building block thus constitutes a three-dimensional array of photo sensors that can be used to detect the Cherenkov light produced by relativistic particles emerging from neutrino interactions. Two building blocks will be sparsely configured to fully explore the IceCube signal with similar instrumented volume, different methodology, improved resolution and complementary field of view, including the galactic plane. One building block will be densely configured to precisely measure atmospheric neutrino oscillations.

GIANT API: an application programming interface for functional genomics.

Science.gov (United States)

Roberts, Andrew M; Wong, Aaron K; Fisk, Ian; Troyanskaya, Olga G

2016-07-08

GIANT API provides biomedical researchers programmatic access to tissue-specific and global networks in humans and model organisms, and associated tools, which includes functional re-prioritization of existing genome-wide association study (GWAS) data. Using tissue-specific interaction networks, researchers are able to predict relationships between genes specific to a tissue or cell lineage, identify the changing roles of genes across tissues and uncover disease-gene associations. Additionally, GIANT API enables computational tools like NetWAS, which leverages tissue-specific networks for re-prioritization of GWAS results. The web services covered by the API include 144 tissue-specific functional gene networks in human, global functional networks for human and six common model organisms and the NetWAS method. GIANT API conforms to the REST architecture, which makes it stateless, cacheable and highly scalable. It can be used by a diverse range of clients including web browsers, command terminals, programming languages and standalone apps for data analysis and visualization. The API is freely available for use at http://giant-api.princeton.edu. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

Building API manufacturing in South Africa

CSIR Research Space (South Africa)

Loots, Glaudina

2017-10-01

Full Text Available projects) Challenges • Lack of relevant skills – process chemistry, process engineering (cGMP standards), project engineering, project management, process operations, maintenance and process quality control and assurance. – platform for skills... development - to enable a sustained pipeline of multidisciplinary skills for the envisaged API industry expansion. – entrepreneurial thinking – attract young talent in establishing niche businesses within the API manufacturing sector. • Small local...

The API petroassist network

International Nuclear Information System (INIS)

Boortz, M.J.; Jardim, G.M.; Horn, S.A.; Disbennett, D.B.

1993-01-01

Past spill responses, such as those in the Exxon Valdez and American Trader incidents, demonstrated the value of companies volunteering their in-house experts and local knowledge to help other companies in spill response. The American Petroleum Institute (API) formed the PetroAssist Network to provide a means for oil companies to readily gain access to the expertise and communications equipment of other oil companies when needed for spill responses. An API work group developed the PetroAssist Network legal agreement and management and activation procedures. To minimize red tape and reduce the burden on members, existing systems were used whenever possible. The network became operational on January 1, 1992, with more than 40 members

The Ruby UCSC API: accessing the UCSC genome database using Ruby.

Science.gov (United States)

Mishima, Hiroyuki; Aerts, Jan; Katayama, Toshiaki; Bonnal, Raoul J P; Yoshiura, Koh-ichiro

2012-09-21

The University of California, Santa Cruz (UCSC) genome database is among the most used sources of genomic annotation in human and other organisms. The database offers an excellent web-based graphical user interface (the UCSC genome browser) and several means for programmatic queries. A simple application programming interface (API) in a scripting language aimed at the biologist was however not yet available. Here, we present the Ruby UCSC API, a library to access the UCSC genome database using Ruby. The API is designed as a BioRuby plug-in and built on the ActiveRecord 3 framework for the object-relational mapping, making writing SQL statements unnecessary. The current version of the API supports databases of all organisms in the UCSC genome database including human, mammals, vertebrates, deuterostomes, insects, nematodes, and yeast.The API uses the bin index-if available-when querying for genomic intervals. The API also supports genomic sequence queries using locally downloaded *.2bit files that are not stored in the official MySQL database. The API is implemented in pure Ruby and is therefore available in different environments and with different Ruby interpreters (including JRuby). Assisted by the straightforward object-oriented design of Ruby and ActiveRecord, the Ruby UCSC API will facilitate biologists to query the UCSC genome database programmatically. The API is available through the RubyGem system. Source code and documentation are available at https://github.com/misshie/bioruby-ucsc-api/ under the Ruby license. Feedback and help is provided via the website at http://rubyucscapi.userecho.com/.

The Ruby UCSC API: accessing the UCSC genome database using Ruby

Science.gov (United States)

2012-01-01

Background The University of California, Santa Cruz (UCSC) genome database is among the most used sources of genomic annotation in human and other organisms. The database offers an excellent web-based graphical user interface (the UCSC genome browser) and several means for programmatic queries. A simple application programming interface (API) in a scripting language aimed at the biologist was however not yet available. Here, we present the Ruby UCSC API, a library to access the UCSC genome database using Ruby. Results The API is designed as a BioRuby plug-in and built on the ActiveRecord 3 framework for the object-relational mapping, making writing SQL statements unnecessary. The current version of the API supports databases of all organisms in the UCSC genome database including human, mammals, vertebrates, deuterostomes, insects, nematodes, and yeast. The API uses the bin index—if available—when querying for genomic intervals. The API also supports genomic sequence queries using locally downloaded *.2bit files that are not stored in the official MySQL database. The API is implemented in pure Ruby and is therefore available in different environments and with different Ruby interpreters (including JRuby). Conclusions Assisted by the straightforward object-oriented design of Ruby and ActiveRecord, the Ruby UCSC API will facilitate biologists to query the UCSC genome database programmatically. The API is available through the RubyGem system. Source code and documentation are available at https://github.com/misshie/bioruby-ucsc-api/ under the Ruby license. Feedback and help is provided via the website at http://rubyucscapi.userecho.com/. PMID:22994508

The Ruby UCSC API: accessing the UCSC genome database using Ruby

Directory of Open Access Journals (Sweden)

Mishima Hiroyuki

2012-09-01

Full Text Available Abstract Background The University of California, Santa Cruz (UCSC genome database is among the most used sources of genomic annotation in human and other organisms. The database offers an excellent web-based graphical user interface (the UCSC genome browser and several means for programmatic queries. A simple application programming interface (API in a scripting language aimed at the biologist was however not yet available. Here, we present the Ruby UCSC API, a library to access the UCSC genome database using Ruby. Results The API is designed as a BioRuby plug-in and built on the ActiveRecord 3 framework for the object-relational mapping, making writing SQL statements unnecessary. The current version of the API supports databases of all organisms in the UCSC genome database including human, mammals, vertebrates, deuterostomes, insects, nematodes, and yeast. The API uses the bin index—if available—when querying for genomic intervals. The API also supports genomic sequence queries using locally downloaded *.2bit files that are not stored in the official MySQL database. The API is implemented in pure Ruby and is therefore available in different environments and with different Ruby interpreters (including JRuby. Conclusions Assisted by the straightforward object-oriented design of Ruby and ActiveRecord, the Ruby UCSC API will facilitate biologists to query the UCSC genome database programmatically. The API is available through the RubyGem system. Source code and documentation are available at https://github.com/misshie/bioruby-ucsc-api/ under the Ruby license. Feedback and help is provided via the website at http://rubyucscapi.userecho.com/.

GIBS API for Developers

Data.gov (United States)

National Aeronautics and Space Administration — API using Global Imagery Browse Services (GIBS) designed to deliver global, full-resolution satellite imagery to users in a highly responsive manner, enabling...

Neutron spectrometer using NE218 liquid scintillator

International Nuclear Information System (INIS)

Dance, J.B.; Francois, P.E.

1976-01-01

A neutron spectrometer has been constructed using NE218 liquid scintillator. Discrimination against electron-gamma events was obtained usng a charge-comparison pulse shape discrimination system. The resolution obtained was about 0.25 MeV F.W.H.M. at 2.0 MeV

Coming 5th Edition of the API Standard 618: major changes compared to the API 618, 4th edition

NARCIS (Netherlands)

Pyle, A.; Eijk, A.; Elferink, H.

2003-01-01

This paper will present the highlights of changes that will be found in the 5th Edition of API 618, which is expected to be published in late 2003 or early 2004. Approximately every 5 years the API Standards are revised in such a way that the latest field experiences and proven designs are included

Letter of intent for KM3NeT 2.0

International Nuclear Information System (INIS)

Adrián-Martínez, S; Ageron, M; Aharonian, F; Aiello, S; Albert, A; Ameli, F; Anassontzis, E; Andre, M; Androulakis, G; Anghinolfi, M

2016-01-01

The main objectives of the KM3NeT Collaboration are (i) the discovery and subsequent observation of high-energy neutrino sources in the Universe and (ii) the determination of the mass hierarchy of neutrinos. These objectives are strongly motivated by two recent important discoveries, namely: (1) the high-energy astrophysical neutrino signal reported by IceCube and (2) the sizable contribution of electron neutrinos to the third neutrino mass eigenstate as reported by Daya Bay, Reno and others. To meet these objectives, the KM3NeT Collaboration plans to build a new Research Infrastructure consisting of a network of deep-sea neutrino telescopes in the Mediterranean Sea. A phased and distributed implementation is pursued which maximises the access to regional funds, the availability of human resources and the synergistic opportunities for the Earth and sea sciences community. Three suitable deep-sea sites are selected, namely off-shore Toulon (France), Capo Passero (Sicily, Italy) and Pylos (Peloponnese, Greece). The infrastructure will consist of three so-called building blocks. A building block comprises 115 strings, each string comprises 18 optical modules and each optical module comprises 31 photo-multiplier tubes. Each building block thus constitutes a three-dimensional array of photo sensors that can be used to detect the Cherenkov light produced by relativistic particles emerging from neutrino interactions. Two building blocks will be sparsely configured to fully explore the IceCube signal with similar instrumented volume, different methodology, improved resolution and complementary field of view, including the galactic plane. One building block will be densely configured to precisely measure atmospheric neutrino oscillations. (paper)

Excitation functions for some evaporation residues identified in the interaction of 20Ne and 93Nb at moderate excitation energies

International Nuclear Information System (INIS)

Agarwal, Avinash; Rizvi, I.A.; Gupta, Meenal; Ahamad, Tauseef; Ghugre, S.S.; Sinha, A.K.; Chaubey, A.K.

2008-01-01

With the motivation of studying the complete and incomplete fusion reactions, excitation functions for the reactions 93 Nb(Ne, p2n) 110 Sn, 93 Nb(Ne, 2pn) 110 In, 93 Nb(Ne, 2p2n) 109 In, 93 Nb(Ne, αn) 108 In, 93 Nb(Neα2n) 107 In and 93 Nb(Ne, α p n) 107 Cd have been measured at the incident energy ranging from 91.4 MeV - 145 MeV. The well established activation technique followed by off line high purity gamma- ray spectroscopy was employed. The measured excitation functions were compared with the statistical model calculations by using the codes ALICE-91 and Pace-4. The effect of variation of different parameters including level density parameter involved in these codes has also been studied. Excellent agreement was found between theoretical and experimental values in some of the fusion evaporation reaction channels. However, significant enhancement of cross-section observed in α-emission channels may be due to incomplete fusion process. (author)

Caractérisation structurale de l'adsorption des isomères para- et meta- du xylène dans la zéolithe de type faujasite BaX Structural Characterization of Para- and Meta- Xylene in Bax Zeolite

Directory of Open Access Journals (Sweden)

Mellot C.

2006-11-01

Full Text Available La séparation du para-xylène des isomères aromatiques en C8 est réalisée industriellement grâce à l'adsorption sur tamis moléculaire zéolithique. Une amélioration des propriétés de séparation des tamis, et en particulier de leur sélectivité, nécessite, entre autres, une bonne connaissance des interactions entre les molécules d'adsorbat et la structure zéolithique. Pour ce faire, nous avons fait appel à deux techniques de caractérisation physico-chimique : la diffraction des neutrons et la spectroscopie infrarouge. Nous avons étudié une zéolithe BaX de type faujasite sur laquelle nous avons adsorbé, à l'état de corps purs, les isomères para- et méta- du xylène. Cette zéolithe est connue industriellement pour ses propriétés sélectives performantes pour le paraxylène. Les analyses ont été réalisées en considérant tout d'abord un faible taux de remplissage, voisin d'une molécule par supercage de zéolithe, et ensuite à saturation où la zéolithe contient sensiblement trois molécules par supercage. La diffraction des neutrons permet, à basse température, de localiser les molécules dans la zéolithe et de préciser leur interaction avec le cation Ba²+. La spectroscopie infrarouge permet une étude des caractéristiques vibrationnelles de l'adsorbat en fonction du taux de recouvrement. Une synthèse des résultats obtenus à l'aide de ces deux méthodes d'investigation nous a permis de dégager un modèle de remplissage des supercages pour les deux isomères considérés. Ainsi, des différences significatives sont mises en évidence. En ce qui concerne le para-xylène, pour un taux de remplissage inférieur à deux molécules par supercage, les molécules de para-xylène viennent se positionner au voisinage des cations en site SII de la supercage. La troisième molécule de para-xylène introduite dans la zéolithe n'est pas en interaction avec un cation Ba²+ et sera localisée dans un nouveau site F

Strangeness production in antiproton annihilation at rest on 3He, 4He and 20Ne

International Nuclear Information System (INIS)

Balestra, F.; Batusov, Yu.A.; Falomkin, I.V.; Pontecorvo, G.B.; Rozhdestvensky, A.M.; Sapozhnikov, M.G.; Tretyak, V.I.; Bendiscioli, G.; Filippini, V.; Rotondi, A.; Salvini, P.; Venaglioni, A.; Bossolasco, S.; Bussa, M.P.; Busso, L.; Fava, L.; Ferrero, L.; Panzieri, D.; Piragino, G.; Tosello, F.; Breivik, F.O.; Danielsen, K.M.; Jacobsen, T.; Soerensen, S.O.; Guaraldo, C.; Maggiora, A.; Haatuft, A.; Halsteinslid, A.; Myklebost, K.; Olsen, J.M.; Lodi Rizzini, E.; Brescia Univ.; Zenoni, A.; European Organization for Nuclear Research, Geneva

1991-01-01

New data are reported on antiproton annihilations at rest with production of Λ and K S 0 , using a streamer chamber with 3 He, 4 He and 20 Ne as gas targets. The data include Λ, K S 0 , ΛK S 0 and K S 0 K S 0 production rates and momentum distributions, π - momentum spectra, mean numbers of charged particles generally and of negatively charged particles separately for different reaction channels. The yields are compared to simple combinatorial calculations based on the extreme assumptions of Λ production via B=1 or via B=0 (anti K rescattering) annihilations. Λ and K S 0 momentum spectra are compared to simple model calculations where B=0 and B=1 annihilations with and without final-state interactions are considered. A review of existing data on Λ and K S 0 production is presented, showing the dependence on the anti p momentum and on the mass number of the target. (orig.)

Comportamentos de abandono e migração de colônias silvestres da abelha melífera africanizada (Apis mellifera L. - DOI: 10.4025/actascibiolsci.v29i4.882 Absconding and migratory behaviors of feral Africanized honey bee (Apis mellifera L. colonies in NE Brazil - DOI: 10.4025/actascibiolsci.v29i4.882

Directory of Open Access Journals (Sweden)

Raimundo Maciel Souza

2008-02-01

Full Text Available Os movimentos de colônias silvestres da abelha melífera africanizada (Apis mellifera L. no Estado do Ceará, Brasil, foram investigados com o objetivo de compreender variações anuais em sua população. A chegada e a partida de colônias de abelhas africanizadas (AHB, no município semi-árido de Canindé e na úmida cidade litorânea de Fortaleza (separadas por 120 km, foram monitoradas semanalmente, de janeiro de 1999 a dezembro de 2001, e comparados com os dados pluviométricos de chuvas em ambas as áreas. Os resultados demonstraram que as abelhas africanizadas somente nidificaram no semi-árido durante a estação chuvosa e o abandonaram na estação seca, ao contrário do observado em Fortaleza. Apenas 5% das colônias permaneceram na área semi-árida por todo o ano, por causa dos ataques de formigas (Camponotus sp. e carência de néctar e água na estação seca. A maioria das colônias migrou para as áreas litorâneas onde o clima é mais ameno e muitas espécies vegetais florescem nesta época do ano. O excesso de chuvas provavelmente forçava as colônias africanizadas a migrarem de volta ao semi-árido durante a estação chuvosa. Conclui-se que o abandono e a migração são estratégias que permitem às abelhas africanizadas sobreviverem no semi-árido nordestino, em contraste com as raças européias que nunca conseguiram estabelecer populações silvestres na região.We investigated the annual movements of feral Africanized honey bee (Apis melliferaL. colonies in the state of Ceará, Brazil, aiming to understand seasonal variations in their population. Arrival and absconding of Africanized honey bee (AHB colonies in the semiarid municipality of Canindé and the coastal humid city of Fortaleza (120 km apart were recorded weekly from January 1999 to December 2001, and the data compared to rainfall records in both areas. Results showed that AHB colonies only nest in the semiarid during the rainy season and abscond during the

Coplanarity of two-proton emissions in 400 MeV/nucleon Ne + NaF, Pb reactions

International Nuclear Information System (INIS)

Tanihata, Isao.

1984-10-01

Two-proton coincidence spectra have been measured in a wide kinematical range for 20 Ne + NaF and 20 Ne + Pb collisions at 400 MeV/nucleon. Coplanar-type correlations show different feature between Ne + NaF and Ne + Pb target reactions. A strong in-plane correlation, which correspond to quasi-elastic scatterings (QES) of nucleons, was observed in wide angular range (15 to 90 0 ) in NaF target collisions. Angular distributions of QES were reproduced reasonably well by a single nucleon-nucleon scattering model. Enhancement of the QES at momentum transfer around t = 2 - 3m/sub π/, which is predicted as an indication of pionic instability, was not observed. In Ne + Pb collisions, an azimuthally asymmetric emission of particles with respect to the beam axis were implied by the anti-coplanar correlation. A new type of coplanar correlation between the emission angle and the momentum suggests a back-to-back emission of projectile and target nucleons. 8 references, 8 figures

[Analysis of different pipe corrosion by ESEM and bacteria identification by API in pilot distribution network].

Science.gov (United States)

Wu, Qing; Zhao, Xinhua; Yu, Qing; Li, Jun

2008-07-01

To understand the corrosion of different material water supply pipelines and bacterium in drinking water and biofilms. A pilot distribution network was built and water quality detection was made on popular pipelines of galvanized iron pipe, PPR and ABS plastic pipes by ESEM (environmental scanning electron microscopy). Bacterium in drinking water and biofilms were identified by API Bacteria Identification System 10s and 20E (Biomerieux, France), and pathogenicity of bacterium were estimated. Galvanized zinc pipes were seriously corroded; there were thin layers on inner face of PPR and ABS plastic pipes. 10 bacterium (got from water samples) were identified by API10S, in which 7 bacterium were opportunistic pathogens. 21 bacterium (got from water and biofilms samples) were identified by API20E, in which 5 bacterium were pathogens and 11 bacterium were opportunistic pathogens and 5 bacteria were not reported for their pathogenicities to human beings. The bacterial water quality of drinking water distribution networks were not good. Most bacterium in drinking water and biofilms on the inner face of pipeline of the drinking water distribution network were opportunistic pathogens, it could cause serious water supply accident, if bacteria spread in suitable conditions. In the aspect of pipe material, old pipelines should be changed by new material pipes.

A Web API ecosystem through feature-based reuse

NARCIS (Netherlands)

Verborgh, Ruben; Dumontier, Michel

2016-01-01

The current Web API landscape does not scale well: every API requires its own hardcoded clients in an unusually short-lived, tightly coupled relationship of highly subjective quality. This directly leads to inflated development costs, and prevents the design of a more intelligent generation of

Practical Implementation of 10 Rules for Writing REST APIs

Directory of Open Access Journals (Sweden)

Jiri Hradil

2017-01-01

Full Text Available This paper shows a practical implementation of “10 Rules for Writing REST APIs introduced in the article” (Hradil, 2016. The application is done in Invoice Home (Wikilane, 2016, an invoicing web application for small business and entrepreneurs available world-wide. The API is implemented in JSON hypermedia format (ECMA International, 2016 and with Ruby on Rails framework (Hansson, 2016. The main purpose of the API is to allow connection of Invoice Home with external systems and offer Invoice Home data in simpler format compared to the current HTML format of the full-stack web application. The paper could be also used as a basic template or pattern for any other implementation of the JSON API in any web-based application.

Building Hypermedia APIs with HTML5 and Node

CERN Document Server

Amundsen, Mike

2011-01-01

With this concise book, you'll learn the art of building hypermedia APIs that don't simply run on the Web, but that actually exist in the Web. You'll start with the general principles and technologies behind this architectural approach, and then dive hands-on into three fully-functional API examples. Too many APIs rely on concepts rooted in desktop and local area network patterns that don't scale well-costly solutions that are difficult to maintain over time. This book shows system architects and web developers how to design and implement human- and machine-readable web services that remain

Influência de essências na alimentação artificial energética na atratividade de Abelhas Apis mellifera

Directory of Open Access Journals (Sweden)

I. P. Almeida Neto

2015-09-01

Full Text Available O objetivo desse trabalho foi avaliar a atratividade de diferentes aromas adicionados a alimentação artificial energética de abelhas Apis mellifera. O delineamento experimental usado foi DIC no qual constou de 11 tratamentos e quatro repetições, sendo os tratamentos os aromas tutti-frutte, erva-doce, maracujá, café, baunilha, morango, amarula, menta, cereja, coco e testemunha (sem aroma e as repetições foram considerados os dias de coleta de dados. Foram feitas observações do fluxo de abelhas a cada cinco minutos fazendo o registro fotográfico para contagem das mesmas. O período de observação ao longo do dia foi de 20 minutos sendo realizado no horário da manhã. Observamos que no decorrer do trabalho o fluxo das abelhas foi aumentando gradativamente em todas as essências a cada repetição sendo que essência que mais atraiu as abelhas foi a amarula (em media 147 abelhas, não deferindo da essência da baunilha, porém a baunilha não diferiu das demais essências.Influence of essences in energy artificial food the bees attractiveness Apis melliferaAbstract: The aim of this study was to evaluate the attractiveness of Apis mellifera by energy added artificial feeding of different aromas. The experimental design used was DIC in which consisted of 11 treatments and four replications, and the treatments the tutti-frutte aromas, fennel, passion fruit, coffee, vanilla, strawberry, amarula, mint, cherry, coconut and control (without aroma and repetitions were considered the days of data collection. Observations of bees stream samples were collected every five minutes making the photographic record to count them. The observation period throughout the day was 20 minutes being held in the morning hours. We note that during the work flow of bees has been increasing gradually in all essences with each repetition being that essence that attracted the bees was amarula (on average 147 bees, not deferring the essence of vanilla, but vanilla

243 ORIGINAL ARTICLE

African Journals Online (AJOL)

boaz

Isolates were identified as A. baumannii using API 20NE and E-test was used to define IRAB. Out of 146 A. ... L'étude des facteurs de risque associe à l'infection IRAB est d'une importance capitale ..... Pimentel JD1, Low J, Styles K, Harris OC,.

The geospatial data quality REST API for primary biodiversity data.

Science.gov (United States)

Otegui, Javier; Guralnick, Robert P

2016-06-01

We present a REST web service to assess the geospatial quality of primary biodiversity data. It enables access to basic and advanced functions to detect completeness and consistency issues as well as general errors in the provided record or set of records. The API uses JSON for data interchange and efficient parallelization techniques for fast assessments of large datasets. The Geospatial Data Quality API is part of the VertNet set of APIs. It can be accessed at http://api-geospatial.vertnet-portal.appspot.com/geospatial and is already implemented in the VertNet data portal for quality reporting. Source code is freely available under GPL license from http://www.github.com/vertnet/api-geospatial javier.otegui@gmail.com or rguralnick@flmnh.ufl.edu Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press.

First Identification of Nosema Ceranae (Microsporidia Infecting Apis Mellifera in Venezuela

Directory of Open Access Journals (Sweden)

Porrini Leonardo P.

2017-06-01

Full Text Available Nosema ceranae is a pathogen of Apis mellifera, which seems to have jumped from its original host Asiatic honey bee Apis ceranae. Nosemosis which affects the honey bee Apis mellifera is caused by two parasitic fungi described as etiologic agents of the disease. Nosema apis was the only microsporidian infection identified in A. mellifera until N. ceranae in Taiwan and Europe. Nosema spp. positive samples of adult worker bees from the Venezuelean state of Lara were determined through light microscopy of spores. Samples were then tested to determine Nosema species (N.apis/N.ceranae using previously reported PCR primers for the 16S rRNA gene. A multiplex PCR assay was used to differentiate both N. apis and N. ceranae species. Only N. ceranae was found in the analyzed samples and the percentage of infected foragers fluctuated between 18% and 60%.

NSLS-II High Level Application Infrastructure And Client API Design

International Nuclear Information System (INIS)

Shen, G.; Yang, L.; Shroff, K.

2011-01-01

The beam commissioning software framework of NSLS-II project adopts a client/server based architecture to replace the more traditional monolithic high level application approach. It is an open structure platform, and we try to provide a narrow API set for client application. With this narrow API, existing applications developed in different language under different architecture could be ported to our platform with small modification. This paper describes system infrastructure design, client API and system integration, and latest progress. As a new 3rd generation synchrotron light source with ultra low emittance, there are new requirements and challenges to control and manipulate the beam. A use case study and a theoretical analysis have been performed to clarify requirements and challenges to the high level applications (HLA) software environment. To satisfy those requirements and challenges, adequate system architecture of the software framework is critical for beam commissioning, study and operation. The existing traditional approaches are self-consistent, and monolithic. Some of them have adopted a concept of middle layer to separate low level hardware processing from numerical algorithm computing, physics modelling, data manipulating, plotting, and error handling. However, none of the existing approaches can satisfy the requirement. A new design has been proposed by introducing service oriented architecture technology. The HLA is combination of tools for accelerator physicists and operators, which is same as traditional approach. In NSLS-II, they include monitoring applications and control routines. Scripting environment is very important for the later part of HLA and both parts are designed based on a common set of APIs. Physicists and operators are users of these APIs, while control system engineers and a few accelerator physicists are the developers of these APIs. With our Client/Server mode based approach, we leave how to retrieve information to the

Proposta de um modelo de referência para governo eletrônico 2.0

OpenAIRE

Dziekaniak, Gisele Vasconcelos

2011-01-01

Propõe-se um modelo de referência para governo eletrônico (e-gov) fundamentado nas prerrogativas da Web 2.0. Este modelo visa contribuir para o desenvolvimento de governos 2.0, os quais são baseados no compartilhamento do conhecimento, bem como na gestão e criação de conteúdos por coletivos e no fortalecimento das relações governo e sociedade. Utiliza-se a pesquisa bibliográfica, assim como a observação direta de redes sociais que possuem como objeto de discussão as plataformas governam...

API and ISO standards can be combined

International Nuclear Information System (INIS)

Weightman, R.T.; Warnack, M.F.

1992-01-01

This paper reports that oil field equipment and product manufacturers can maintain a competitive advantage and minimize costs by integrating American Petroleum Institute (API) licensing programs with International Standards Organization (ISO) 9001 standards under one quality system. A combined quality system approach can position a company for quality system certification under ISO 9001 while maintaining API specifications. Furthermore, only one quality system manual is needed for API licensing and ISO certification, avoiding duplication of effort. The benefits of a documented quality program include the flowing: Job descriptions and personnel qualification requirements are documented; The improved documentation allows direct tracing of specific production activities; Laboratory test methods and calibration of test equipment follow accepted standards for more reliable and reproducible test data; Quality control becomes proactive, not reactive, through internal process controls previously not implemented; Employee attitudes improve through appreciation for the overall goals of the company; Ambiguous quality issues, such as documenting special customer requirements, are easily resolved; and The company image improves with customers, particularly for those that require API Specification Q1 or ISO 9001 compliance or those having their own quality performance standards

Competencias informaticas para el e-learning 2.0

Directory of Open Access Journals (Sweden)

Gabriel Valerio Ureña

2011-06-01

Full Text Available La sociedad del conocimiento ha alterado la forma en que la humanidad trabaja, se divierte y aprende; de ahí el surgimiento del denominado e–learning, una modalidad educativa cuya “innovación” ha sido cuestionada por la tendencia a simular formas tradicionales de educar. Esta investigación explora el concepto de e–learning 2.0 y los principios del conectivismo como marco de referencia. El objetivo principal de este trabajo de investigación fue identificar las competencias informáticas que necesitará un estudiante universitario para responder a lo que se anticipa como la modalidad del e–learning 2.0. La investigación, de naturaleza cualitativa, fue realizada en una institución de educación superior privada, con un grupo de 21 estudiantes y recién egresados de una carrera en particular y 13 profesores universitarios.

Uso da parafina incorporada à cera alveolada em colônias de abelhas Apis mellifera L. africanizadas para produção de mel Paraffin incorporation to beewax foundation in Apis mellifera L. Africanized colonies for honey production

Directory of Open Access Journals (Sweden)

Vagner de Alencar Arnaut de Toledo

2002-04-01

Full Text Available O objetivo foi avaliar favos construídos a partir de três tratamentos, lâminas de cera alveolada, lâminas de cera alveolada com parafina e parte do quadro sem cera. Foram utilizadas dez colônias de abelhas africanizadas, Apis mellifera L. (Hymenoptera, Apidae existentes na região de Marialva, Estado do Paraná. Foram efetuados mapeamentos da área construída e ocupada com mel, a intervalos de aproximadamente 20 dias. Três quadros, cada um contendo os três tratamentos foram colocados nas posições lateral esquerda, central e lateral direita da melgueira vista por trás da colméia. As abelhas construíram a maior área e ocuparam com mel (p The aim of this paper was the evaluation of combs from three experimental treatments: beeswax foundation, beeswax with paraffin and a gap frame, partially without wax. The experiment was carried out using ten Apis mellifera L. (Hymenoptera, Apidae Africanized honeybee colonies in Marialva - state of Paraná, in the south of Brazil. They were accomplished by mapping areas constructed and occupied with honey, at intervals of approximately 20 days. Three combs, containing, each one, the three treatments were placed at the positions right lateral, central and left lateral of the super observed the hive to the back. The honeybees built the greatest area and filled with honey (p < 0.05 when the comb was introduced in the central position of the hive, compared to other treatments in which differences were also observed (p < 0.05. The position of the wax comb mixed with paraffin produced the smallest area (p < 0.05 occupied with honey compared to the others. Results showed that paraffin mixed with wax comb should be used since the combs are placed in the central position and must be used for production of honey in sections.

Estudo das glândulas mandibulares e ovários de operárias de Apis mellifera L. (Hymenoptera, Apidae mantidas em condiçoes artificiais

Directory of Open Access Journals (Sweden)

Claudia Regina de Salvo

1988-01-01

Full Text Available Foram estudados os ovários e as glândulas mandibulares de Apis mellifera mantidas em condições artificiais e foi observado que em pequenos grupos (menos de 20 abelhas os órgãos analisados não se desenvolveram.The ovaries and mandibular glands in workers of Apis mellifera under artificial conditions were studied and was observed that in small groups (less than 20 bees the analyzed organs did not develop.

LAS GALERÍAS, CONSTRUCCIONES PARA ALUMBRAR AGUA DE FREÁTICOS PRÓXIMOS EN EL NE DE LA REGIÓN DE MURCIA: MINADOS CON ESPEJUELOS EN JUMILLA

Directory of Open Access Journals (Sweden)

J. Mª. Gómez Espín,

2007-01-01

Full Text Available En el Sureste de la Península Ibérica, existen áreas que no cuentan con recursos de aguas en superfi cie, por lo que para el abastecimiento de la población y ganado, así como para el riego, tradicionalmente se ha recurrido al aprovechamiento de freáticos mediante sistemas de galerías filtrantes «qanat-s»; llamados también galerías con lumbreras y en el NE de la Región de Murcia «minados con espejuelos». En el término municipal de Jumilla (Murcia se han localizado varios de estos sistemas: Montesinos, La Pedrera, Las Puntillas, La Alquería, Los Manaores, Fuente del Pino, Los Estanquicos, Los Álamos, Los Inques,... Cada uno de ellos ha constituido un sistema local de recursos propios de agua en un medio árido y semiárido como el Sureste.

Índices de prevalencia del ácaro Varroa destructor (Acari: Varroidae en cuadros de cría nuevos o previamente utilizados por Apis mellifera (Hymenoptera: Apidae

Directory of Open Access Journals (Sweden)

Jorge, A. MARCANGELI

2007-01-01

Full Text Available El objetivo de esta investigación fue comparar los niveles de infestación de Varroa destructor (Anderson & Trueman en panales de cría nuevos y viejos, en colonias de la abeja criolla (híbrido de Apis mellifera mellifera (Linnaeus y Apis mellifera ligustica Spinola. El trabajo se llevó a cabo en un apiario ubicado en Coronel Vidal, provincia de Buenos Aires, durante la primavera del año 2005. Se trabajó sobre 20 colmenas tipo Langstroth, de un híbrido de Apis mellifera (Linnaeus infestadas naturalmente por el ácaro Varroa destructor, y seleccionadas al azar. En cada una de ellas se escogió un panal de 2 años (viejo que se colocó en el centro del nido de cría, junto con un panal recientemente labrado por las abejas (nuevo. Luego de que ambos cuadros fueran operculados, se los extrajo y se llevaron al laboratorio para su posterior análisis. Cada una de las celdas de cría se desoperculó e inspeccionó en busca de ácaros, registrándose el número de hembras de ácaros que habían ingresado para su reproducción, se calculó el nivel de infestación como el cociente entre el número de celdas infestadas por ácaros y el número total de celdas inspeccionadas. Los resultados mostraron que los panales viejos presentaron niveles de infestación significativamente superiores a los registrados en panales nuevos (13,52% ± 3,35 y 6,18% ± 2,12 respectivamente; t = 10,62; p = 1,9 E-9; g. l.= 19. El mismo patrón fue observado en el número promedio de ácaros por panal (443,3 ± 70,54 y 217,85 ± 51,76 para panales viejos y nuevos respectivamente; t = 23,87; p = 1,24 E-15; g. l.= 19. Los ácaros presentan una marcada preferencia por los panales viejos. Esta selección estaría guiada por olores propios de las celdas, que actuarían como atrayentes. Además, posiblemente enmascaran su presencia de esta manera y evitan así ser detectados y eliminados por las abejas nodrizas mediante los comportamientos higiénicos.

Estudo do comportamento do aço API 5L X80 quando submetido à soldagem por processo automatizado Study on the behavior of API 5L X80 steel when subjected to automated welding process

Directory of Open Access Journals (Sweden)

Siderley Fernandes Albuquerque

2012-06-01

Full Text Available No Brasil, a soldagem de tubulações tem sido praticamente de forma manual, entretanto, a utilização de processos de soldagem automatizados têm crescido muito nos últimos anos, contribuindo para o maior controle dos parâmetros de soldagem, e conseqüentemente, a possibilidade de obtenção de juntas soldadas com melhores propriedades mecânicas. A soldagem de tubulações com aço API 5L X80 ainda vem sendo avaliada no Brasil no que diz respeito aos melhores procedimentos, parâmetros e processos de soldagem; a aplicação de processos automatizados nas condições específicas de campo constitui em uma opção ainda incipiente no país por se discutir ainda a relação custo/benefício com a sua implantação. Logo, o objetivo deste trabalho é avaliar o comportamento na ZTA de juntas soldadas do aço API 5L X80 utilizados para transporte de petróleo e gás quando submetidos à soldagem com diferentes parâmetros, procedimentos e processos de soldagem, incluindo o processo automatizado; os resultados indicam além da redução da extensão e do tamanho de grão da ZTA a preservação da estrutura bainítica do metal de base nesta região nas soldagem executadas com processos automatizados.The welding of pipes has been largely manual in Brazil, however, the use of automated welding processes have greatly increased in recent years, contributing to greater control of welding parameters, and consequently, the possibility of obtaining welded joints with better mechanical properties. The welding of pipes of API 5L X80 steel has been evaluated in Brazil considering to best practices, parameters and welding processes; the implementation of automated processes in the specific field conditions is relevant project and innovative design in this area. Therefore, the objective is to evaluate the behavior in the HAZ of the API 5L X80 steel used for transporting oil and gas when subjected to automated welding processes; the results indicated besides the

The Web as an API.

Energy Technology Data Exchange (ETDEWEB)

Roman, J. H. (Jorge H.)

2001-01-01

As programmers we have worked with many Application Development Interface API development kits. They are well suited for interaction with a particular system. A vast source of information can be made accessible by using the http protocol through the web as an API. This setup has many advantages including the vast knowledge available on setting web servers and services. Also, these tools are available on most hardware and operating system combinations. In this paper I will cover the various types of systems that can be developed this way, their advantages and some drawbacks of this approach. Index Terms--Application Programmer Interface, Distributed applications, Hyper Text Transfer Protocol, Web.

Cross-linking BioThings APIs through JSON-LD to facilitate knowledge exploration.

Science.gov (United States)

Xin, Jiwen; Afrasiabi, Cyrus; Lelong, Sebastien; Adesara, Julee; Tsueng, Ginger; Su, Andrew I; Wu, Chunlei

2018-02-01

Application Programming Interfaces (APIs) are now widely used to distribute biological data. And many popular biological APIs developed by many different research teams have adopted Javascript Object Notation (JSON) as their primary data format. While usage of a common data format offers significant advantages, that alone is not sufficient for rich integrative queries across APIs. Here, we have implemented JSON for Linking Data (JSON-LD) technology on the BioThings APIs that we have developed, MyGene.info , MyVariant.info and MyChem.info . JSON-LD provides a standard way to add semantic context to the existing JSON data structure, for the purpose of enhancing the interoperability between APIs. We demonstrated several use cases that were facilitated by semantic annotations using JSON-LD, including simpler and more precise query capabilities as well as API cross-linking. We believe that this pattern offers a generalizable solution for interoperability of APIs in the life sciences.

Privacy Issues of the W3C Geolocation API

OpenAIRE

Doty, Nick; Mulligan, Deirdre K.; Wilde, Erik

2010-01-01

The W3C's Geolocation API may rapidly standardize the transmission of location information on the Web, but, in dealing with such sensitive information, it also raises serious privacy concerns. We analyze the manner and extent to which the current W3C Geolocation API provides mechanisms to support privacy. We propose a privacy framework for the consideration of location information and use it to evaluate the W3C Geolocation API, both the specification and its use in the wild, and recommend s...

Calibration of a NE213 detector for neutron spectroscopy; Calibracion de un detector de NE213 para espectroscopia de neutrones

Energy Technology Data Exchange (ETDEWEB)

Blazquez Martinez, J; Butragueno Casado, J L

1974-07-01

This work describes the experimental way followed for getting the calibration of a NE213 detector with a beam of neutrons from the J.E.N. 2 MeV Van de Graaff and using at once pulse shape discrimination. Detector has been used for measuring the spectrum of the fast reactor CORAL-1. There is also included an experimental method in order to get with precision where the Compton edge is placed on the electron spectrum. (Author) 9 refs.

NE2561 and NE2611A - are they different?

International Nuclear Information System (INIS)

Huntley, R.; Boas, J.; Kotler, L.; Webb, D.; Stucki, G.

2000-01-01

Full text: Evidence is mounting that the nominally identical ionization chamber types NE2561 and NE2611A have significantly different energy dependences. This is revealed by comparing the radiation quality correction factors k q . The factor k q is the ratio of the absorbed dose to water calibration factors (for a particular type of ionization chamber) at radiation quality Q to that for 60 Co. k q values for NE2561 and NE2611A chambers have been compared for various kV and MV X-ray beams at several standards laboratories. Measurements at ARPANSA (Australia) on six NE2561 and five NE2611A show a consistent difference in k q of 1-2% for 16 and 19 MV X-rays. Work at OFMET (Switzerland) has shown similar differences at 6 and 18 MV. No such differences are seen at NPL (UK) - this inconsistency is currently ascribed to differences in the radiation beams. Consistent differences of up to 3% between these two chamber types have been observed at both ARPANSA and NRC (Canada) at the BIPM medium energy X-ray intercomparison qualities between 50 kV and 250 kV. We conclude that the two types of chamber should not be regarded as identical. ARPANSA and several other laboratories in Europe and North America will shortly participate in a Euromet project to be coordinated by OFMET, to investigate high energy X-ray beam quality specifiers. This project will provide additional data that may lead to a better understanding of this anomaly. Copyright (2000) Australasian College of Physical Scientists and Engineers in Medicine

Influence of humidity on the phase behavior of API/polymer formulations.

Science.gov (United States)

Prudic, Anke; Ji, Yuanhui; Luebbert, Christian; Sadowski, Gabriele

2015-08-01

Amorphous formulations of APIs in polymers tend to absorb water from the atmosphere. This absorption of water can induce API recrystallization, leading to reduced long-term stability during storage. In this work, the phase behavior of different formulations was investigated as a function of relative humidity. Indomethacin and naproxen were chosen as model APIs and poly(vinyl pyrrolidone) (PVP) and poly(vinyl pyrrolidone-co-vinyl acetate) (PVPVA64) as excipients. The formulations were prepared by spray drying. The water sorption in pure polymers and in formulations was measured at 25°C and at different values of relative humidity (RH=25%, 50% and 75%). Most water was absorbed in PVP-containing systems, and water sorption was decreasing with increasing API content. These trends could also be predicted in good agreement with the experimental data using the thermodynamic model PC-SAFT. Furthermore, the effect of absorbed water on API solubility in the polymer and on the glass-transition temperature of the formulations was predicted with PC-SAFT and the Gordon-Taylor equation, respectively. The absorbed water was found to significantly decrease the API solubility in the polymer as well as the glass-transition temperature of the formulation. Based on a quantitative modeling of the API/polymer phase diagrams as a function of relative humidity, appropriate API/polymer compositions can now be selected to ensure long-term stable amorphous formulations at given storage conditions. Copyright © 2015 Elsevier B.V. All rights reserved.

Identification of Staphylococcus species with the API STAPH-IDENT system.

Science.gov (United States)

Kloos, W E; Wolfshohl, J F

1982-01-01

The API STAPH-IDENT system was compared with conventional methods for the identification of 14 Staphylococcus species. Conventional methods included the Kloos and Schleifer simplified scheme and DNA-DNA hybridization. The API STAPH-IDENT strip utilizes a battery of 10 miniaturized biochemical tests, including alkaline phosphatase, urease, beta-glucosidase, beta-glucuronidase, and beta-galactosidase activity, aerobic acid formation from D-(+)-mannose, D-mannitol, D-(+)-trehalose, and salicin, and utilization of arginine. Reactions of cultures were determined after 5 h of incubation at 35 degrees C. Results indicated a high degree of congruence (greater than 90%) between the expedient API system and conventional methods for most species. The addition of a test for novobiocin susceptibility to the API system increased the accuracy of identification of S. saprophyticus, S. cohnii, and S. hominis, significantly. Several strains of S. hominis, S. haemolyticus, and S. warneri which were difficult to separate with the Kloos and Schleifer simplified scheme were accurately resolved by the API system. PMID:6752190

Half-life of the superallowed β+ emitter Ne18

Science.gov (United States)

Grinyer, G. F.; Smith, M. B.; Andreoiu, C.; Andreyev, A. N.; Ball, G. C.; Bricault, P.; Chakrawarthy, R. S.; Daoud, J. J.; Finlay, P.; Garrett, P. E.; Hackman, G.; Hyland, B.; Leslie, J. R.; Morton, A. C.; Pearson, C. J.; Phillips, A. A.; Schumaker, M. A.; Svensson, C. E.; Valiente-Dobón, J. J.; Williams, S. J.; Zganjar, E. F.

2007-08-01

The half-life of Ne18 has been determined by detecting 1042-keV γ rays in the daughter F18 following the superallowed-Fermi β+ decay of samples implanted at the center of the 8πγ-ray spectrometer, a spherical array of 20 HPGe detectors. Radioactive Ne18 beams were produced on-line, mass-separated, and ionized using an electron-cyclotron-resonance ionization source at the ISAC facility at TRIUMF in Vancouver, Canada. This is the first high-precision half-life measurement of a superallowed Fermi β decay to utilize both a large-scale HPGe spectrometer and the isotope separation on-line technique. The half-life of Ne18, 1.6656 ± 0.0019 s, deduced following a 1.4σ correction for detector pulse pile-up, is four times more precise than the previous world average. As part of an investigation into potential systematic effects, the half-life of the heavier isotope Ne23 was determined to be 37.11 ± 0.06 s, a factor of 2 improvement over the previous precision.

EKSPLORASI AKTINOMISET SEBAGAI PENGHASIL ANTIBIOTIKA DARI TANAH MANGROVE Sonneratia caseolaris DI TANJUNG API API

Directory of Open Access Journals (Sweden)

Awalul Fatiqin

2015-08-01

Full Text Available Actinomycetes are soil organisms that have traits that are common to bacteria and fungi but also have quite different characteristics that limit into one group which is distinctly different. Study aimed to explore the mangrove actinomycetes from soil and tested the antibacterial potency. Soil samples taken from the mangrove land at Tanjung Api-api mangrove species Sonneratia caseolaris. Activity test antibacterial using a method modified disk a test bacterium Escherichia coli. Identification isolates of actinomycetes by observing the character of macroscopic colonies, microscopic conidia. The results showed that the obtained three different actinomycetes isolates, 1 isolate has the most potential ability to inhibit bacterial growth test with an average value of 1:13 cm in inhibiting the bacteria Escherichia coli.

Performance indicators for carrier-based DPIs: Carrier surface properties for capsule filling and API properties for in vitro aerosolisation.

Science.gov (United States)

Faulhammer, E; Zellnitz, S; Wutscher, T; Stranzinger, S; Zimmer, A; Paudel, A

2018-01-30

This study investigates engineered carrier, as well as engineered API particles, and shows that there are distinct performance indicators of particle engineering for carrier-based dry powder inhalers (DPIs). Spray dried (SDSS) and jet-milled (JMSS) salbutamol sulphate (SS) was blended with untreated α-lactose monohydrate (LAC_R) and α-lactose monohydrate engineered (LAC_E). Subsequent capsule filling was performed with different process settings on a dosator nozzle capsule filling machine in order to reach a target fill weight of 20-25 mg. To evaluate the performance of the different mixtures, in vitro lung deposition experiments were carried out with a next generation impactor, the emitted dose (ED) and fine particle fraction (FPF) were calculated based on the specification of the European pharmacopoeia. The FPF of micronised powder blends is significantly higher (20%) compared to the FPF of spray dried blends (5%). Compared to API engineering, carrier engineering had a positive effect on the capsule filling performance (weight variability and mean fill weight) at lower compression ratios (setting 1). Results further showed that higher compression ratios appear to be beneficial in terms of capsule filling performance (higher fill weight and less fill weight variation). Concluding, it can be stated that the carrier engineering, or generally carrier properties, govern downstream processing, whereas the API engineering and API properties govern the aerosolisation performance and thereby significantly affect the dose delivery to the lungs. Copyright © 2017 Elsevier B.V. All rights reserved.

A Monte Carlo modeling alternative for the API Gamma Ray Calibration Facility

International Nuclear Information System (INIS)

Galford, J.E.

2017-01-01

The gamma ray pit at the API Calibration Facility, located on the University of Houston campus, defines the API unit for natural gamma ray logs used throughout the petroleum logging industry. Future use of the facility is uncertain. An alternative method is proposed to preserve the gamma ray API unit definition as an industry standard by using Monte Carlo modeling to obtain accurate counting rate-to-API unit conversion factors for gross-counting and spectral gamma ray tool designs. - Highlights: • A Monte Carlo alternative is proposed to replace empirical calibration procedures. • The proposed Monte Carlo alternative preserves the original API unit definition. • MCNP source and materials descriptions are provided for the API gamma ray pit. • Simulated results are presented for several wireline logging tool designs. • The proposed method can be adapted for use with logging-while-drilling tools.

DSA lifetime measurements in 21Ne at high recoil velocity

International Nuclear Information System (INIS)

Grawe, H.; Heidinger, F.; Kaendler, K.

1977-01-01

States in 21 Ne up to 5 MeV excitation energy have been populated using the inverted reaction 2 H( 20 Ne,pγ). The Doppler shift attenuation (DSA) analysis of the pγ coincidence spectra taken in a Ge(Li) detector at 45 0 and 135 0 and an annular silicon surface barrier detector near 0 0 yielded the lifetimes of 8 states in 21 Ne. Due to the large recoil of vi/c approximately equal to 4% three new lifetimes were determined for the short lived levels at 2.80, 4.68 and 4.73 MeV, namely 10 +- 4 fs, 16 +- 4 fs and 10 +- 4 fs, respectively. The results are compared with rotational and shell model calculations. (orig.) [de

Experimental ion mobility measurements in Ne-N2

International Nuclear Information System (INIS)

Cortez, A.F.V.; Encarnação, P.M.C.C.; Santos, F.P.; Borges, F.I.G.M.; Conde, C.A.N.; Veenhof, R.; Neves, P.N.B.

2016-01-01

Data on ion mobility is important to improve the performance of large volume gaseous detectors, such as the ALICE TPC or in the NEXT experiment. In the present work the method, experimental setup and results for the ion mobility measurements in Ne-N 2 mixtures are presented. The results for this mixture show the presence of two peaks for different gas ratios of Ne-N 2 , low reduced electric fields, E / N , 10–20 Td (2.4–4.8 kV·cm −1 ·bar −1 ), low pressures 6–8 Torr (8–10.6 mbar) and at room temperature.

Circumferential welding of API X80 steel pipes; Soldagem circunferencial em tubos de aco da classe API X80

Energy Technology Data Exchange (ETDEWEB)

Castello Branco, J.F.; Bott, Ivani de S. [Pontificia Univ. Catolica do Rio de Janeiro, RJ (Brazil). Dept. de Ciencia dos Materiais e Metalurgia]. E-mails: joaofcb@uol.com.br; bott@dcmm.puc-rio.br; Fedele, R.A. [Boehler Thyssen Welding, Sao Paulo, SP (Brazil)]. E-mail: engenharia@btwbr.com.br; Souza, Luis Felipe G. de [Centro Federal de Educacao Tecnologica Celso Suckow da Fonseca (CEFET-RJ), Rio de Janeiro, RJ (Brazil). Dept. de Engenharia Industrial Mecanica]. E-mail: lfelipe@cefet-rj.br

2003-07-01

The present work is a part of an extensive program for the development of API 5L Gr.X80 grade steel , produced by the well-known UOE production process, for pipeline fabrication. The current stage of this program involves the characterization and performance evaluation/qualification of girth welds produced by Shield Metal Arc Weld (SMAW) under simulated field conditions, with tubes fixed in the horizontal position. Three types of electrodes were utilized for the basic tasks; the root pass, the hot pass and fill and cap passes. The root pass was carried out with an E-6010 electrode to avoid incomplete joint penetration. The hot pass, applied over the root pass, was performed with an E-9010-G electrode. The fill and cap passes were executed with E-10018-G electrodes. The welded joints produced were evaluated according to the API 1104 specification, which requires: side bend, nick- break and tensile tests. Additionally, non-destructive tests, Charpy-V impact tests and metallographic characterization were undertaken. It was verified that this welding procedure, based on three types of electrodes, could produce welded joints in accordance to the API 1104 specification. These results ensure the applicability of the API 5L Gr. X80 steel developed in this research project for use in pipeline construction. (author)

Análise físico-química dos méis das abelhas Apis mellifera e Melipona scutellaris produzidos em regiões distintas no Estado da Paraíba

Directory of Open Access Journals (Sweden)

Evangelista-Rodrigues Adriana

2005-01-01

Full Text Available O mel de abelhas é um produto muito apreciado, no entanto, de fácil adulteração com açúcares ou xaropes. Desta forma, é necessário que haja algumas análises para a determinação da sua qualidade para que seja comercializado. Este trabalho teve como objetivo fazer a análise físico-química dos méis de abelha Apis mellifera. e Melipona scutellaris para a comparação entre as espécies e entre as localidades do Brejo e do Cariri (regiões do Estado da Paraíba. Observou-se que o mel de abelha nativa apresenta um maior teor de água (umidade de 25,25% quando comparado com o mel de abelha africanizada (18,76%, dificultando o seu armazenamento, pois o alto teor de água do produto diminui a sua vida útil de prateleira. Para as análises de hidroximetilfurfural, o valor mais alto foi para o mel produzido na região do Cariri, quando comparado com o mel produzido na região do Brejo, o que pode ser explicado pela diferença de temperatura, sendo mais alta no Cariri. Para os valores de pH, obteve-se diferença significativa entre os méis, com o mel do Cariri apresentando valor mais baixo (3,8. Para Acidez Total, o mel de abelha africanizada do Brejo Paraibano apresentou 41,6 meq/kg de mel, enquanto o mel de abelha nativa apresentou 28,3 meq/kg de mel. Para os demais parâmetros estudados, não houve diferença significativa entre os tratamentos. Conclui-se que os méis produzidos pelas abelhas africanizadas (A. mellifera e pela abelha nativa Melipona scutellaris na Estação Experimental do Cariri e da Chã-de-Jardim pertencentes ao CCA/UFPB apresentam valores diferentes dos padrões da Regulamento Técnico de Identidade e Qualidade do Mel (Ministério da Agricultura e do Abastecimento para alguns parâmetros, o que pode dificultar o seu armazenamento por um longo período.

DarkJS: Entorno online para el desarrollo de WebApps

OpenAIRE

Ramírez Gallardo, Sergio

2014-01-01

El objetivo global de este proyecto, es crear un editor de WebApps cómodo, eficiente y completo que permita a los desarrolladores abstraerse de las diversidad de plataformas, de las APIs gráficas y de la interacción cliente/servidor, para poder centrarse en desarrollar sus productos y servicios.

Resisting majesty: Apis cerana, has lower antennal sensitivity and decreased attraction to queen mandibular pheromone than Apis mellifera

OpenAIRE

Shihao Dong; Ping Wen; Qi Zhang; Xinyu Li; Ken Tan; James Nieh

2017-01-01

In highly social bees, queen mandibular pheromone (QMP) is vital for colony life. Both Apis cerana (Ac) and Apis mellifera (Am) share an evolutionarily conserved set of QMP compounds: (E)-9-oxodec-2-enoic acid (9-ODA), (E)-9-hydroxydec-2-enoic acid (9-HDA), (E)-10-hydroxy-dec-2-enoic acid (10-HDA), 10-hydroxy-decanoic acid (10-HDAA), and methyl p?hydroxybenzoate (HOB) found at similar levels. However, evidence suggests there may be species-specific sensitivity differences to QMP compounds bec...

Fulltext PDF

Indian Academy of Sciences (India)

2013-04-20

Apr 20, 2013 ... foreign brand such as API-NE; whereas in automated iden- tification systems such as Phoenix and VITEK ID, only identification cards or panels cost around 25 US dollars per sample. In addition, they require sophisticated and costly automated machines. Table 4. Primers and PCR conditions used for the ...

Predominant Api m 10 sensitization as risk factor for treatment failure in honey bee venom immunotherapy

DEFF Research Database (Denmark)

Frick, Marcel; Fischer, Jörg; Helbing, Arthur

2016-01-01

BACKGROUND: Component resolution recently identified distinct sensitization profiles in honey bee venom (HBV) allergy, some of which were dominated by specific IgE to Api m 3 and/or Api m 10, which have been reported to be underrepresented in therapeutic HBV preparations. OBJECTIVE: We performed...... responders and nonresponders regarding levels of IgE sensitization to Api m 1, Api m 2, Api m 3, and Api m 5. In contrast, Api m 10 specific IgE was moderately but significantly increased in nonresponders. Predominant Api m 10 sensitization (>50% of specific IgE to HBV) was the best discriminator...... (specificity, 95%; sensitivity, 25%) with an odds ratio of 8.444 (2.127-33.53; P = .0013) for treatment failure. Some but not all therapeutic HBV preparations displayed a lack of Api m 10, whereas Api m 1 and Api m 3 immunoreactivity was comparable to that of crude HBV. In line with this, significant Api m 10...

Production of the Ne Auger electrons by Ne/sup +/ bombardment of Mg and Al surfaces

Energy Technology Data Exchange (ETDEWEB)

Ferrante, J; Pepper, S V [National Aeronautics and Space Administration, Cleveland, Ohio (USA). Lewis Research Center

1976-07-01

The authors have bombarded Mg and Al surfaces with Ne/sup +/ ions and in this letter present evidence for the production of an inner shell vacancy in the Ne by the asymmetric Ne-Mg and Ne-Al collision. In addition, autoionization states of neutral Ne have been observed. These states are to be distinguished from the more usual case in Auger electron spectroscopy of de-excitation of an ion with a core vacancy.

Investigation into process-induced de-aggregation of cohesive micronised API particles.

Science.gov (United States)

Hoffmann, Magnus; Wray, Patrick S; Gamble, John F; Tobyn, Mike

2015-09-30

The aim of this study was to assess the impact of unit processes on the de-aggregation of a cohesive micronised API within a pharmaceutical formulation using near-infrared chemical imaging. The impact on the primary API particles was also investigated using an image-based particle characterization system with integrated Raman analysis. The blended material was shown to contain large, API rich domains which were distributed in-homogeneously across the sample, suggesting that the blending process was not aggressive enough to disperse aggregates of micronised drug particles. Cone milling, routinely used to improve the homogeneity of such cohesive formulations, was observed to substantially reduce the number and size of API rich domains; however, several smaller API domains survived the milling process. Conveyance of the cone milled formulation through the Alexanderwerk WP120 powder feed system completely dispersed all remaining aggregates. Importantly, powder feed transmission of the un-milled formulation was observed to produce an equally homogeneous API distribution. The size of the micronised primary drug particles remained unchanged during powder feed transmission. These findings provide further evidence that this powder feed system does induce shear, and is in fact better able to disperse aggregates of a cohesive micronised API within a blend than the blend-mill-blend step. Crown Copyright © 2015. Published by Elsevier B.V. All rights reserved.

Macelignan inhibits bee pathogenic fungi Ascophaera apis growth through HOG1 pathway

Directory of Open Access Journals (Sweden)

Y.K. Shin

2016-01-01

Full Text Available Ascosphaera apis is a bee pathogen that causes bee larvae infection disease, to which treatment is not yet well investigated. The aim of this study was to investigate antifungal susceptibility in vitro against A. apis and to identify a new antifungal agent for this pathogen through minimal inhibitory concentration (MIC assay and western blot analysis. Macelignan had 1.56 and 3.125 μg/mL MIC against A. apis after 24 and 48 h, respectively, exhibiting the strongest growth inhibition against A. apis among the tested compounds (corosolic acid, dehydrocostus lactone, loganic acid, tracheloside, fangchinoline and emodin-8-O-β-D-glucopyranoside. Furthermore, macelignan showed a narrow-ranged spectrum against various fungal strains without any mammalian cell cytotoxicity. In spite of miconazole having powerful broad-ranged anti-fungal activity including A. apis, it demonstrated strong cytotoxicity. Therefore, even if macelignan alone was effective as an antifungal agent to treat A. apis, combined treatment with miconazole was more useful to overcome toxicity, drug resistance occurrence and cost effectiveness. Finally, HOG1 was revealed as a target molecule of macelignan in the anti-A. apis activity by inhibiting phosphorylation using S. cerevisiae as a model system. Based on our results, macelignan, a food-grade antimicrobial compound, would be an effective antifungal agent against A. apis infection in bees.

IgE recognition of chimeric isoforms of the honeybee (Apis mellifera) venom allergen Api m 10 evaluated by protein array technology.

Science.gov (United States)

Van Vaerenbergh, Matthias; De Smet, Lina; Rafei-Shamsabadi, David; Blank, Simon; Spillner, Edzard; Ebo, Didier G; Devreese, Bart; Jakob, Thilo; de Graaf, Dirk C

2015-02-01

Api m 10 has recently been established as novel major allergen that is recognized by more than 60% of honeybee venom (HBV) allergic patients. Previous studies suggest Api m 10 protein heterogeneity which may have implications for diagnosis and immunotherapy of HBV allergy. In the present study, RT-PCR revealed the expression of at least nine additional Api m 10 transcript isoforms by the venom glands. Two distinct mechanisms are responsible for the generation of these isoforms: while the previously known variant 2 is produced by an alternative splicing event, novel identified isoforms are intragenic chimeric transcripts. To the best of our knowledge, this is the first report of the identification of chimeric transcripts generated by the honeybee. By a retrospective proteomic analysis we found evidence for the presence of several of these isoforms in the venom proteome. Additionally, we analyzed IgE reactivity to different isoforms by protein array technology using sera from HBV allergic patients, which revealed that IgE recognition of Api m 10 is both isoform- and patient-specific. While it was previously demonstrated that the majority of HBV allergic patients display IgE reactivity to variant 2, our study also shows that some patients lacking IgE antibodies for variant 2 display IgE reactivity to two of the novel identified Api m 10 variants, i.e. variants 3 and 4. Copyright © 2014 Elsevier Ltd. All rights reserved.

Why and How Java Developers Break APIs

OpenAIRE

Brito, Aline; Xavier, Laerte; Hora, Andre; Valente, Marco Tulio

2018-01-01

Modern software development depends on APIs to reuse code and increase productivity. As most software systems, these libraries and frameworks also evolve, which may break existing clients. However, the main reasons to introduce breaking changes in APIs are unclear. Therefore, in this paper, we report the results of an almost 4-month long field study with the developers of 400 popular Java libraries and frameworks. We configured an infrastructure to observe all changes in these libraries and t...

FLORESCIMENTO INDUZIDO DA JUREMA PRETA PARA FORNECER PÓLEN À ABELHA MELÍFERA NA ESTIAGEM DA CAATINGA

Directory of Open Access Journals (Sweden)

ALINE DOS SANTOS SILVA

2015-01-01

Full Text Available The aim of this study was to investigate the possibility of increasing pollen supply to honey bees (Apis mellifera during the dry season in Caatinga (shrub vegetation of NE Brazil by inducing Mimosa tenui-flora to bloom. The work was carried out from August to December 2012 in Altamira Apícola Apiaries, situat-ed at Limoeiro do Norte – Ceará, Brazil. The experiment comprised three phases: Phase 1 – the amount of wa-ter needed to induce the blooming of Mimosa tenuiflora (T0L, T250L, T500L, T750L and T1000L; Phase 2 – Floral biology and flower visitors; Phase 3 – pollen harvested by the colonies and percentage of M. tenuiflora in the honey bee diet by sampling and comparing pollen loads from colonies placed 20m with those more than 3km away from the induced plants. Results of the Phase 1 showed that the treatments 3, 4 and 5 induced blooming, and T1000L produced a greater number of inflorescences (p <0.05. Blooming reached its peak eight days after induction. Hymenoptera represented more than 95% of floral visitors with Apis mellifera, Trigona spinipes and Melipona subnitida as the most frequent bee species. Palynological analyses carried out in phase 3 showed a significant (p<0,05 increment in pollen collection and the participation of M. tenuiflora pollen in the diet of colonies situated 20 meters from the induced plants. Induction of flowering Mimosa tenuiflora increased the supply and collection of pollen by bees in the critical period of the year, minimizing the effect of drought on the colonies.

Pro REST API development with nodejs

CERN Document Server

Doglio, Fernando

2015-01-01

Pro REST API Development with Node.js is your guide to managing and understanding the full capabilities of successful REST development. API design is a hot topic in the programming world, but not many resources exist for developers to really understand how you can leverage the advantages. This book will provide a brief background on REST and the tools it provides (well known and not so well known). Understand how there is more to REST than just JSON and URLs. You will then cover and compare the maintained modules currently available in the npm community, including Express, Restify, Vatican,

Durability of API class B cement pastes exposed to aqueous solutions containing chloride, sulphate and magnesium ions

Directory of Open Access Journals (Sweden)

Hernández, M. E.

2008-12-01

Full Text Available This paper discusses a durability study conducted on API class B cement, the type used in shallow oil wells, when exposed to aggressive formation water. Its resistance to the major ions, namely –SO4=, Mg+2 and Cl-–, is related both to its capacity to assimilate the aggressive action of each harmful agent and to the changes in the chemical reactivity of some of its components. The methodology used consisted in preparing and immersing cement specimens in neutral solutions containing variable concentrations of these ions to monitor the chemical reactions taking place. These solutions were analyzed and XRD studies were conducted for over a year to identify mineralogical variations. The purposes of the study were to determine the effects of joint ionic attack on this kind of cement and to monitor the variations in the calcium concentration in the aqueous solutions of Na2SO4, MgCl2 and NaCl in contact with API class B cement pastesEste trabajo se basa en el estudio de la durabilidad de un cemento API clase B, utilizado en pozos petrolíferos someros, frente a la agresividad de las aguas de formación a las que puede estar expuesto. Su eficacia frente a la exposición a los iones más importantes –SO4=, Mg+2 y Cl-– se relaciona con su capacidad de asimilar la acción agresiva de cada agente perjudicial, así como de las reacciones químicas que sufra por la reactividad de alguno de sus compuestos. La metodología aplicada supone la preparación de probetas de este cemento y su inmersión en disoluciones neutras, conteniendo los referidos iones a distintas concentraciones, para evaluar el desarrollo de las reacciones existentes en su seno. A tal fin se realizaron análisis de las disoluciones y estudios de DRX durante más de un año para conocer su evolución mineralógica. El objetivo del trabajo ha sido determinar los efectos resultantes de los ataques conjuntos de los citados iones al referido cemento; así como la observación de las

The connection between cluster and collective quadrupole channels in 20 Ne and E 2-transition probabilities between the bound and continuous spectrum states

International Nuclear Information System (INIS)

Bystrenko, A.V.; Okhrimenko, I.P.

1993-01-01

The E 2-transition probabilities between the discrete and continuous spectrum states in 20 Ne are investigated using the two-channel version (making allowance for the connection between cluster and quadrupole channels) of the consistent microscopic approach,an algebraic version of the resonating-group method. The correctness of the approximation of the continuous spectrum by the discrete states, which is usual in collective models, the quadrupole sum rule and the giant quadrupole resonance phenomenon are considered. (author). 2 tab., 12 figs

rApi m 3 and rApi m 10 improve detection of honey bee sensitization in Hymenoptera venom-allergic patients with double sensitization to honey bee and yellow jacket venom.

Science.gov (United States)

Frick, M; Müller, S; Bantleon, F; Huss-Marp, J; Lidholm, J; Spillner, E; Jakob, T

2015-12-01

Recombinant allergens improve the diagnostic precision in Hymenoptera venom allergy (HVA), in particular in patients with double sensitization to both honey bee (HBV) and yellow jacket venom (YJV). While currently available vespid allergens allow the detection of >95% of YJV-allergic patients, the sensitization frequency to the only available HBV marker allergen rApi m 1 in HBV-allergic patients is lower. Here, we demonstrate that sIgE to additional HBV marker allergens rApi m 3 and rApi m 10 allows the detection of genuine HBV sensitization in 46-65% of Api m 1 negative sera. This is of particular relevance in patients with double sensitization to HBV and YJV that did not identify the culprit insect. Addition of sIgE to rApi m 3 and rApi m 10 provides evidence of HBV sensitization in a large proportion of rApi m 1-negative patients and thus provides a diagnostic marker and rationale for VIT treatment with HBV, which otherwise would have been missing. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Integrated platform and API for electrophysiological data.

Science.gov (United States)

Sobolev, Andrey; Stoewer, Adrian; Leonhardt, Aljoscha; Rautenberg, Philipp L; Kellner, Christian J; Garbers, Christian; Wachtler, Thomas

2014-01-01

Recent advancements in technology and methodology have led to growing amounts of increasingly complex neuroscience data recorded from various species, modalities, and levels of study. The rapid data growth has made efficient data access and flexible, machine-readable data annotation a crucial requisite for neuroscientists. Clear and consistent annotation and organization of data is not only an important ingredient for reproducibility of results and re-use of data, but also essential for collaborative research and data sharing. In particular, efficient data management and interoperability requires a unified approach that integrates data and metadata and provides a common way of accessing this information. In this paper we describe GNData, a data management platform for neurophysiological data. GNData provides a storage system based on a data representation that is suitable to organize data and metadata from any electrophysiological experiment, with a functionality exposed via a common application programming interface (API). Data representation and API structure are compatible with existing approaches for data and metadata representation in neurophysiology. The API implementation is based on the Representational State Transfer (REST) pattern, which enables data access integration in software applications and facilitates the development of tools that communicate with the service. Client libraries that interact with the API provide direct data access from computing environments like Matlab or Python, enabling integration of data management into the scientist's experimental or analysis routines.

A Monte Carlo modeling alternative for the API Gamma Ray Calibration Facility.

Science.gov (United States)

Galford, J E

2017-04-01

The gamma ray pit at the API Calibration Facility, located on the University of Houston campus, defines the API unit for natural gamma ray logs used throughout the petroleum logging industry. Future use of the facility is uncertain. An alternative method is proposed to preserve the gamma ray API unit definition as an industry standard by using Monte Carlo modeling to obtain accurate counting rate-to-API unit conversion factors for gross-counting and spectral gamma ray tool designs. Copyright © 2017 Elsevier Ltd. All rights reserved.

grlc Makes GitHub Taste Like Linked Data APIs

NARCIS (Netherlands)

Meroño-Peñuela, A.; Hoekstra, Rinke; Sack, H; Rizzo, G; Steinmetz, N; Mladenić, D; Auer, S; Lange, C

2016-01-01

Building Web APIs on top of SPARQL endpoints is becoming a common practice to enable universal access to the integration favorable dataspace of Linked Data. However, the Linked Data community cannot expect users to learn SPARQL to query this dataspace, and Web APIs are the most extended way of

grlc Makes GitHub Taste Like Linked Data APIs

NARCIS (Netherlands)

Meroño-Peñuela, A.; Hoekstra, R.

2016-01-01

Building Web APIs on top of SPARQL endpoints is becoming a common practice to enable universal access to the integration favorable dataspace of Linked Data. However, the Linked Data community cannot expect users to learn SPARQL to query this dataspace, and Web APIs are the most common way of

Experience API: Flexible, Decentralized and Activity-Centric Data Collection

Science.gov (United States)

Kevan, Jonathan M.; Ryan, Paul R.

2016-01-01

This emerging technology report describes the Experience API (xAPI), a new e-learning specification designed to support the learning community in standardizing and collecting both formal and informal distributed learning activities. Informed by Activity Theory, a framework aligned with constructivism, data is collected in the form of activity…

Scattering study of the Ne + NeH{sup +}(v{sub 0} = 0, j{sub 0} = 0) → NeH{sup +} + Ne reaction on an ab initio based analytical potential energy surface

Energy Technology Data Exchange (ETDEWEB)

Koner, Debasish; Panda, Aditya N., E-mail: adi07@iitg.ernet.in [Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781039 (India); Barrios, Lizandra; González-Lezana, Tomás, E-mail: t.gonzalez.lezana@csic.es [IFF-CSIC, Instituto de Física Fundamental, CSIC, Serrano 123, Madrid 28006 (Spain)

2016-01-21

Initial state selected dynamics of the Ne + NeH{sup +}(v{sub 0} = 0, j{sub 0} = 0) → NeH{sup +} + Ne reaction is investigated by quantum and statistical quantum mechanical (SQM) methods on the ground electronic state. The three-body ab initio energies on a set of suitably chosen grid points have been computed at CCSD(T)/aug-cc-PVQZ level and analytically fitted. The fitting of the diatomic potentials, computed at the same level of theory, is performed by spline interpolation. A collinear [NeHNe]{sup +} structure lying 0.72 eV below the Ne + NeH{sup +} asymptote is found to be the most stable geometry for this system. Energies of low lying vibrational states have been computed for this stable complex. Reaction probabilities obtained from quantum calculations exhibit dense oscillatory structures, particularly in the low energy region and these get partially washed out in the integral cross section results. SQM predictions are devoid of oscillatory structures and remain close to 0.5 after the rise at the threshold thus giving a crude average description of the quantum probabilities. Statistical cross sections and rate constants are nevertheless in sufficiently good agreement with the quantum results to suggest an important role of a complex-forming dynamics for the title reaction.

Widespread dispersal of the microsporidian Nosema ceranae, an emergent pathogen of the western honey bee, Apis mellifera.

Science.gov (United States)

Klee, Julia; Besana, Andrea M; Genersch, Elke; Gisder, Sebastian; Nanetti, Antonio; Tam, Dinh Quyet; Chinh, Tong Xuan; Puerta, Francisco; Ruz, José Maria; Kryger, Per; Message, Dejair; Hatjina, Fani; Korpela, Seppo; Fries, Ingemar; Paxton, Robert J

2007-09-01

The economically most important honey bee species, Apis mellifera, was formerly considered to be parasitized by one microsporidian, Nosema apis. Recently, [Higes, M., Martín, R., Meana, A., 2006. Nosema ceranae, a new microsporidian parasite in honeybees in Europe, J. Invertebr. Pathol. 92, 93-95] and [Huang, W.-F., Jiang, J.-H., Chen, Y.-W., Wang, C.-H., 2007. A Nosema ceranae isolate from the honeybee Apis mellifera. Apidologie 38, 30-37] used 16S (SSU) rRNA gene sequences to demonstrate the presence of Nosema ceranae in A. mellifera from Spain and Taiwan, respectively. We developed a rapid method to differentiate between N. apis and N. ceranae based on PCR-RFLPs of partial SSU rRNA. The reliability of the method was confirmed by sequencing 29 isolates from across the world (N =9 isolates gave N. apis RFLPs and sequences, N =20 isolates gave N. ceranae RFLPs and sequences; 100% correct classification). We then employed the method to analyze N =115 isolates from across the world. Our data, combined with N =36 additional published sequences demonstrate that (i) N. ceranae most likely jumped host to A. mellifera, probably within the last decade, (ii) that host colonies and individuals may be co-infected by both microsporidia species, and that (iii) N. ceranae is now a parasite of A. mellifera across most of the world. The rapid, long-distance dispersal of N. ceranae is likely due to transport of infected honey bees by commercial or hobbyist beekeepers. We discuss the implications of this emergent pathogen for worldwide beekeeping.

A RESTful API for accessing microbial community data for MG-RAST.

Directory of Open Access Journals (Sweden)

Andreas Wilke

2015-01-01

Full Text Available Metagenomic sequencing has produced significant amounts of data in recent years. For example, as of summer 2013, MG-RAST has been used to annotate over 110,000 data sets totaling over 43 Terabases. With metagenomic sequencing finding even wider adoption in the scientific community, the existing web-based analysis tools and infrastructure in MG-RAST provide limited capability for data retrieval and analysis, such as comparative analysis between multiple data sets. Moreover, although the system provides many analysis tools, it is not comprehensive. By opening MG-RAST up via a web services API (application programmers interface we have greatly expanded access to MG-RAST data, as well as provided a mechanism for the use of third-party analysis tools with MG-RAST data. This RESTful API makes all data and data objects created by the MG-RAST pipeline accessible as JSON objects. As part of the DOE Systems Biology Knowledgebase project (KBase, http://kbase.us we have implemented a web services API for MG-RAST. This API complements the existing MG-RAST web interface and constitutes the basis of KBase's microbial community capabilities. In addition, the API exposes a comprehensive collection of data to programmers. This API, which uses a RESTful (Representational State Transfer implementation, is compatible with most programming environments and should be easy to use for end users and third parties. It provides comprehensive access to sequence data, quality control results, annotations, and many other data types. Where feasible, we have used standards to expose data and metadata. Code examples are provided in a number of languages both to show the versatility of the API and to provide a starting point for users. We present an API that exposes the data in MG-RAST for consumption by our users, greatly enhancing the utility of the MG-RAST service.

The development, validity, and reliability of the Addiction Profile Index (API).

Science.gov (United States)

Ögel, Kültegin; Evren, Cüneyt; Karadağ, Figen; Gürol, Defne Tamar

2012-01-01

The objective of this study was to develop a practical questionnaire for multidimensional assessment of problems associated with alcohol and substance abuse that would also be useful for treatment planning. The Addiction Profile Index (API) is a self-report questionnaire consisting of 37 items and the following 5 subscales: characteristics of substance use; dependency diagnosis; the effects of subsance use on the user; craving; motivation to quit using substances. The study included 345 alcohol and/or substance abusers from 2 addiction treatment clinics and a prison addiction service. The validity of the questionnaire was assessed using the Michigan Alcoholism Screening Test (MAST), Readiness to Change Questionnaire (SOCRATES), Penn Alcohol Craving Scale (PACS), Drug Craving Scale (DCS), Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), and Addiction Severity Index (ASI). The Cronbach's alpha coefficient for the total API was 0.89 and for the subscales it ranged from 0.63 to 0.86. Item-total correlation coefficients ranged from 0.42 to 0.89. The Spearman Brown split-half method coefficient for the total API was 0.83. In all, 4 factors were obtained using explanatory factor analysis that represented 52.3% of the total variance. The API craving subscale was observed to be consistent with PACS and the API motivation subscale was consistent with SOCRATES. The API total score was strongly correlated with the mean MAST score, and the composite ASI medical status, substance use, legal status, and family social relations subscale scores. Based on ROC analyses, the area under curve was 0.90. With a total API cut-off score of 4, the scale's sensitivity and specificity 0.85 was 0.78, respectively. The findings show that the API is a valid and reliable questionnaire that can be used to measure the severity of different dimensions of substance dependency.

A RESTful API for accessing microbial community data for MG-RAST.

Science.gov (United States)

Wilke, Andreas; Bischof, Jared; Harrison, Travis; Brettin, Tom; D'Souza, Mark; Gerlach, Wolfgang; Matthews, Hunter; Paczian, Tobias; Wilkening, Jared; Glass, Elizabeth M; Desai, Narayan; Meyer, Folker

2015-01-01

Metagenomic sequencing has produced significant amounts of data in recent years. For example, as of summer 2013, MG-RAST has been used to annotate over 110,000 data sets totaling over 43 Terabases. With metagenomic sequencing finding even wider adoption in the scientific community, the existing web-based analysis tools and infrastructure in MG-RAST provide limited capability for data retrieval and analysis, such as comparative analysis between multiple data sets. Moreover, although the system provides many analysis tools, it is not comprehensive. By opening MG-RAST up via a web services API (application programmers interface) we have greatly expanded access to MG-RAST data, as well as provided a mechanism for the use of third-party analysis tools with MG-RAST data. This RESTful API makes all data and data objects created by the MG-RAST pipeline accessible as JSON objects. As part of the DOE Systems Biology Knowledgebase project (KBase, http://kbase.us) we have implemented a web services API for MG-RAST. This API complements the existing MG-RAST web interface and constitutes the basis of KBase's microbial community capabilities. In addition, the API exposes a comprehensive collection of data to programmers. This API, which uses a RESTful (Representational State Transfer) implementation, is compatible with most programming environments and should be easy to use for end users and third parties. It provides comprehensive access to sequence data, quality control results, annotations, and many other data types. Where feasible, we have used standards to expose data and metadata. Code examples are provided in a number of languages both to show the versatility of the API and to provide a starting point for users. We present an API that exposes the data in MG-RAST for consumption by our users, greatly enhancing the utility of the MG-RAST service.

JEnsembl: a version-aware Java API to Ensembl data systems.

Science.gov (United States)

Paterson, Trevor; Law, Andy

2012-11-01

The Ensembl Project provides release-specific Perl APIs for efficient high-level programmatic access to data stored in various Ensembl database schema. Although Perl scripts are perfectly suited for processing large volumes of text-based data, Perl is not ideal for developing large-scale software applications nor embedding in graphical interfaces. The provision of a novel Java API would facilitate type-safe, modular, object-orientated development of new Bioinformatics tools with which to access, analyse and visualize Ensembl data. The JEnsembl API implementation provides basic data retrieval and manipulation functionality from the Core, Compara and Variation databases for all species in Ensembl and EnsemblGenomes and is a platform for the development of a richer API to Ensembl datasources. The JEnsembl architecture uses a text-based configuration module to provide evolving, versioned mappings from database schema to code objects. A single installation of the JEnsembl API can therefore simultaneously and transparently connect to current and previous database instances (such as those in the public archive) thus facilitating better analysis repeatability and allowing 'through time' comparative analyses to be performed. Project development, released code libraries, Maven repository and documentation are hosted at SourceForge (http://jensembl.sourceforge.net).

Upon a Message-Oriented Trading API

Directory of Open Access Journals (Sweden)

Claudiu VINTE

2010-01-01

Full Text Available In this paper, we introduce the premises for a trading system application-programming interface (API based on a message-oriented middleware (MOM, and present the results of our research regarding the design and the implementation of a simulation-trading system employing a service-oriented architecture (SOA and messaging. Our research has been conducted with the aim of creating a simulation-trading platform, within the academic environment, that will provide both the foundation for future experiments with trading systems architectures, components, APIs, and the framework for research on trading strategies, trading algorithm design, and equity markets analysis tools. Mathematics Subject Classification: 68M14 (distributed systems.

grlc Makes GitHub Taste Like Linked Data APIs

NARCIS (Netherlands)

Merono Penuela, A.; Hoekstra, R.J.

2016-01-01

Building Web APIs on top of SPARQL endpoints is becoming common practice. It enables universal access to the integration favorable data space of Linked Data. In the majority of use cases, users cannot be expected to learn SPARQL to query this data space. Web APIs are the most common way to enable

Hot-stage microscopy for determination of API particles in a formulated tablet.

Science.gov (United States)

Simek, Michal; Grünwaldová, Veronika; Kratochvíl, Bohumil

2014-01-01

Although methods exist to readily determine the particle size distribution (PSD) of an active pharmaceutical ingredient (API) before its formulation into a final product, the primary challenge is to develop a method to determine the PSD of APIs in a finished tablet. To address the limitations of existing PSD methods, we used hot-stage microscopy to observe tablet disintegration during temperature change and, thus, reveal the API particles in a tablet. Both mechanical and liquid disintegration were evaluated after we had identified optimum milling time for mechanical disintegration and optimum volume of water for liquid disintegration. In each case, hot-stage micrographs, taken before and after the API melting point, were compared with image analysis software to obtain the PSDs. Then, the PSDs of the APIs from the disintegrated tablets were compared with the PSDs of raw APIs. Good agreement was obtained, thereby confirming the robustness of our methodology. The availability of such a method equips pharmaceutical scientists with an in vitro assessment method that will more reliably determine the PSD of active substances in finished tablets.

Hot-Stage Microscopy for Determination of API Particles in a Formulated Tablet

Directory of Open Access Journals (Sweden)

Michal Šimek

2014-01-01

Full Text Available Although methods exist to readily determine the particle size distribution (PSD of an active pharmaceutical ingredient (API before its formulation into a final product, the primary challenge is to develop a method to determine the PSD of APIs in a finished tablet. To address the limitations of existing PSD methods, we used hot-stage microscopy to observe tablet disintegration during temperature change and, thus, reveal the API particles in a tablet. Both mechanical and liquid disintegration were evaluated after we had identified optimum milling time for mechanical disintegration and optimum volume of water for liquid disintegration. In each case, hot-stage micrographs, taken before and after the API melting point, were compared with image analysis software to obtain the PSDs. Then, the PSDs of the APIs from the disintegrated tablets were compared with the PSDs of raw APIs. Good agreement was obtained, thereby confirming the robustness of our methodology. The availability of such a method equips pharmaceutical scientists with an in vitro assessment method that will more reliably determine the PSD of active substances in finished tablets.

USANDO LA WEB 2.0 PARA INFORMARSE E INFORMAR. UNA EXPERIENCIA EN EDUCACIÓN SUPERIOR

Directory of Open Access Journals (Sweden)

Andrea Francisco Amat

2011-04-01

Full Text Available En un contexto donde la información se ha convertido en la principal material prima y las pantallas inundan el espacio público y privado, las instituciones educativas han de proporcionar herramientas para la comprensión del mundo en el que se vive, la promoción del pensamiento crítico o la construcción de una ciudadanía activa y responsable. En este sentido, la lectura crítica de los mass media y la producción de mensajes mediáticos por parte del estudiantado se torna fundamental.Para ello, el rol del docente ha de cambiar para convertirse en un facilitador de espacios de aprendizaje que permitan al estudiantado adquirir las competencias necesarias para enfrentarse a los retos del siglo XXI y la Web 2.0 se convierte en una herramienta pedagógica interesante para aprender haciendo, buscando, interactuando y colaborando (Cobo y Pardo, 2007.El presente artículo tiene como finalidad difundir una experiencia de innovación educativa que se ha desarrollado en la Universitat Jaume I de Castellón (España donde el estudiantado de Educación Cívica y Social ha utilizado la Web 2.0 para buscar información, seleccionarla y analizarla para luego producir sus propios discursos informativos tanto textuales como audiovisuales al mismo tiempo que se alfabetizaban digitalmente. El proyecto fue evaluado por el estudiantado a través de un cuestionario tipo Likert y sus resultados mostraron una alta valoración tanto de la introducción de las TIC en la asignatura como del aprendizaje producido por el planteamiento de trabajo.

ChemSpell Web Service API

Data.gov (United States)

U.S. Department of Health & Human Services — The ChemSpell Web Service API provides chemical name spell checking and chemical name synonym look-up. ChemSpell contains more than 1.3 million chemical names...

Safe “cloudification” of large images through picker APIs

Science.gov (United States)

Bremer, Erich; Kurc, Tahsin; Gao, Yi; Saltz, Joel; Almeida, Jonas S

2016-01-01

The “Box model” allows users with no particular training in informatics, or access to specialized infrastructure, operate generic cloud computing resources through a temporary URI dereferencing mechanism known as “drop-file-picker API” (“picker API” for sort). This application programming interface (API) was popularized in the web app development community by DropBox, and is now a consumer-facing feature of all major cloud computing platforms such as Box.com, Google Drive and Amazon S3. This reports describes a prototype web service application that uses picker APIs to expose a new, “cloudified”, API tailored for image analysis, without compromising the private governance of the data exposed. In order to better understand this cross-platform cloud computing landscape, we first measured the time for both transfer and traversing of large image files generated by whole slide imaging (WSI) in Digital Pathology. The verification that there is extensive interconnectivity between cloud resources let to the development of a prototype software application that exposes an image-traversing REST API to image files stored in any of the consumer-facing “boxes”. In summary, an image file can be upload/synchronized into a any cloud resource with a file picker API and the prototype service described here will expose an HTTP REST API that remains within the safety of the user’s own governance. The open source prototype is publicly available at sbu-bmi.github.io/imagebox. Availability The accompanying prototype application is made publicly available, fully functional, with open source, at http://sbu-bmi.github.io/imagebox://sbu-bmi.github.io/imagebox. An illustrative webcasted use of this Web App is included with the project codebase at https://github.com/SBU-BMI/imageboxs://github.com/SBU-BMI/imagebox. PMID:28269829

Complementarity and completed trials: reforming the Ne bis in idem ...

African Journals Online (AJOL)

Nnamdi Azikiwe University Journal of International Law and Jurisprudence ... This paper is concerned with the question whether article 20(3) of the Rome Statute is ... Rome Statute, Ne bis in idem, double jeopardy, International Criminal Court ...

SjAPI, the first functionally characterized Ascaris-type protease inhibitor from animal venoms.

Directory of Open Access Journals (Sweden)

Zongyun Chen

Full Text Available BACKGROUND: Serine protease inhibitors act as modulators of serine proteases, playing important roles in protecting animal toxin peptides from degradation. However, all known serine protease inhibitors discovered thus far from animal venom belong to the Kunitz-type subfamily, and whether there are other novel types of protease inhibitors in animal venom remains unclear. PRINCIPAL FINDINGS: Here, by screening scorpion venom gland cDNA libraries, we identified the first Ascaris-type animal toxin family, which contains four members: Scorpiops jendeki Ascaris-type protease inhibitor (SjAPI, Scorpiops jendeki Ascaris-type protease inhibitor 2 (SjAPI-2, Chaerilus tricostatus Ascaris-type protease inhibitor (CtAPI, and Buthus martensii Ascaris-type protease inhibitor (BmAPI. The detailed characterization of Ascaris-type peptide SjAPI from the venom gland of scorpion Scorpiops jendeki was carried out. The mature peptide of SjAPI contains 64 residues and possesses a classical Ascaris-type cysteine framework reticulated by five disulfide bridges, different from all known protease inhibitors from venomous animals. Enzyme and inhibitor reaction kinetics experiments showed that recombinant SjAPI was a dual function peptide with α-chymotrypsin- and elastase-inhibiting properties. Recombinant SjAPI inhibited α-chymotrypsin with a Ki of 97.1 nM and elastase with a Ki of 3.7 μM, respectively. Bioinformatics analyses and chimera experiments indicated that SjAPI contained the unique short side chain functional residues "AAV" and might be a useful template to produce new serine protease inhibitors. CONCLUSIONS/SIGNIFICANCE: To our knowledge, SjAPI is the first functionally characterized animal toxin peptide with an Ascaris-type fold. The structural and functional diversity of animal toxins with protease-inhibiting properties suggested that bioactive peptides from animal venom glands might be a new source of protease inhibitors, which will accelerate the

PARA'04 Workshop on State-of-the-art in Scientific Computing, June 20-23, 2004: Complementary Proceedings

DEFF Research Database (Denmark)

Dongarra, Jack; Madsen, Kaj; Wasniewski, Jerzy

2004-01-01

, was held in Lyngby, Denmark, June 20-23, 2004. The PARA'04 Workshop was organized by Jack Dongarra from the University of Tennessee and Oak Ridge National Laboratory, and Kaj Madsen and Jerzy Wasniewski from the Technical University of Denmark. The emphasis here was shifted to High-Performance Computing...... (HPC). The ongoing development of ever more advanced computers provides the potential for solving increasingly dif cult computational problems. However, given the complexity of modern computer architectures, the task of realizing this potential needs careful attention. For example, the failure......The PARA workshops in the past have been devoted to parallel computing methods in science and technology. There have been seven PARA meetings to date: PARA'94, PARA'95 and PARA'96 in Lyngby, Denmark, PARA'98 in Umeå, Sweden, PARA'2000 in Bergen, Norway, PARA'02 in Espoo, Finland, and PARA'04 again...

Study of dissipative collisions of 20Ne (MeV/≅7-11 nucleon)+ 27Al

International Nuclear Information System (INIS)

Dey, Aparajita; Bhattacharya, C.; Bhattacharya, S.; Rana, T. K.; Kundu, S.; Banerjee, K.; Mukhopadhyay, S.; Banerjee, S. R.; Gupta, D.; Saha, R.

2007-01-01

The inclusive energy distributions of complex fragments (3≤9) emitted in the reactions 20 Ne (145, 158, 200, 218 MeV) + 27 Al have been measured in the angular range 10 deg. - 50 deg. The fusion-fission and the deep-inelastic components of the fragment yield have been extracted using multiple Gaussian functions from the experimental fragment energy spectra. The elemental yields of the fusion-fission component have been found to be fairly well explained in the framework of the standard statistical model. It is found that strong competition occurs between the fusion-fission and the deep-inelastic processes at these energies. The time scale of the deep-inelastic process was estimated to be typically in the range of ∼10 -21 -10 -22 s, and it was found to decrease with increasing fragment mass. The angular momentum dissipations in the fully energy damped deep-inelastic process have been estimated from the average energies of the deep-inelastic components of the fragment energy spectra. The estimated angular momentum dissipations, for lighter fragments in particular, are found to be greater than those predicted by the empirical sticking limit

Study of sulphate-reducing bacteria corrosion in the weld joint for API X-70 steel

Directory of Open Access Journals (Sweden)

Flores, J. E.

2012-10-01

Full Text Available The corrosion behavior originated by sulfate-reducing bacteria (SRB was studied in two regions of welded API X-70 steel pipeline. The studies were focused on base material (BM and heat affected zone (HAZ, from the internal region of the pipe. SRB were extracted from oil and grown in a Postgate medium. Corrosion was evaluated at 60 °C for times between 5 and 64 days. Potentiodynamic polarization curves, obtained by electrochemical techniques, indicated surface activation at short times. Structural and morphological characterizations were carried out by scanning electron microscopy (SEM and optical microscopy (OM. H₂S concentration and pH were also measured. Results showed an important increase in the corrosion damage up to 20 days, influenced by the SRB activity, which lead to a maximum of H₂S (pH minimum. It was found a localized corrosion attack in the HAZ in a higher quantity compared to BM; and the formation of a thin film on the steel surface, originated by corrosion products and bacterial activity.

El comportamiento ante la corrosión, originada por bacterias sulfato-reductoras (SRB, fue estudiado en dos regiones de un tubo de acero soldado API X-70. Los estudios se enfocaron en el material base (BM y la zona afectada térmicamente (HAZ, en la parte interna del tubo. Las SRB fueron extraídas del petróleo y cultivadas en un medio Postgate. El comportamiento a la corrosión fue evaluado a una temperatura de 60 °C, por periodos comprendidos entre 5 y 64 días. El análisis de las curvas de polarización potenciodinámicas, obtenidas por técnicas electroquímicas, indicó la activación de la superficie para tiempos cortos. La superficie fue caracterizada estructural y morfológicamente mediante microscopia electrónica de barrido (SEM, así como mediante microscopía óptica (OM. La concentración de H₂S y el pH también fueron medidos. Los resultados mostraron un aumento importante de la corrosi

Comportamiento a la Corrosión del Acero API X70 Soldado por el Proceso de Doble Arco Sumergido Inmerso en Diferentes Medios Corrosivos

Directory of Open Access Journals (Sweden)

Omar Francisco Montes

Full Text Available Resumen Los aceros API X70 son aplicados en fabricación y construcción de tuberías para el transporte de hidrocarburos, sin embargo, a un lapso de tiempo se degradan debido al medio ambiente al cual están expuestos; influyendo en la velocidad y tipo de corrosión sobre las superficies del metal base (MB, zona afectada por el calor (ZAC y zona de fusión (ZF. A fin de conocer y evaluar la susceptibilidad a la corrosión en uniones del acero API X70 sometido a diferentes medios corrosivos, varias pruebas se llevaron a cabo por el proceso de soldadura de doble arco sumergido (DSAW, por sus siglas en inglés, las cuales fueron inmersas en diferentes electrolitos: Cloruro de Sodio (NaCl al 3,5% y Agua (H2O a temperatura ambiente para conocer su comportamiento. Se utilizaron técnicas electroquímicas de ruido electroquímico (RE y curvas de polarización cíclica (CPC para obtener velocidad y tipo de corrosión producida en cada una de las muestras analizadas, incluyendo las tres zonas: MB, ZAC y ZF. Además, se utilizaron técnicas de caracterización como microscopía óptica (MO y microscopía electrónica de barrido (MEB para el análisis superficial. La mayoría de las soldaduras presentan corrosión mixta, con mayores velocidades de corrosión en 3,5% de NaCl.

A quick guide to API 510 certified pressure vessel inspector syllabus example questions and worked answers

CERN Document Server

Matthews, Clifford

2010-01-01

The API Individual Certification Programs (ICPs) are well established worldwide in the oil, gas, and petroleum industries. This Quick Guide is unique in providing simple, accessible and well-structured guidance for anyone studying the API 510 Certified Pressure Vessel Inspector syllabus by summarizing and helping them through the syllabus and providing multiple example questions and worked answers.Technical standards are referenced from the API 'body of knowledge' for the examination, i.e. API 510 Pressure vessel inspection, alteration, rerating; API 572 Pressure vessel inspection; API

The Ensembl REST API: Ensembl Data for Any Language.

Science.gov (United States)

Yates, Andrew; Beal, Kathryn; Keenan, Stephen; McLaren, William; Pignatelli, Miguel; Ritchie, Graham R S; Ruffier, Magali; Taylor, Kieron; Vullo, Alessandro; Flicek, Paul

2015-01-01

We present a Web service to access Ensembl data using Representational State Transfer (REST). The Ensembl REST server enables the easy retrieval of a wide range of Ensembl data by most programming languages, using standard formats such as JSON and FASTA while minimizing client work. We also introduce bindings to the popular Ensembl Variant Effect Predictor tool permitting large-scale programmatic variant analysis independent of any specific programming language. The Ensembl REST API can be accessed at http://rest.ensembl.org and source code is freely available under an Apache 2.0 license from http://github.com/Ensembl/ensembl-rest. © The Author 2014. Published by Oxford University Press.

APIs for QoS configuration in Software Defined Networks

DEFF Research Database (Denmark)

Caba, Cosmin Marius; Soler, José

2015-01-01

The OpenFlow (OF) protocol is widely used in Software Defined Networking (SDN) to realize the communication between the controller and forwarding devices. OF allows great flexibility in managing traffic flows. However, OF alone is not enough to build more complex SDN services that require complete...... such as configuration of devices, ports, queues, etc. An Application Programming Interface (API) for dynamic configuration of QoS resources in the network devices is implemented herein, by using the capabilities of OVSDB. Further, the paper demonstrates the possibility to create network services with coarse granularity...... on top of the fine granular services exposed by the QoS configuration API at the SDNC. A series of tests emphasize the capabilities and the performance of the implemented QoS configuration API....

Sterile Neutrino Searches in MiniBooNE and MicroBooNE

Energy Technology Data Exchange (ETDEWEB)

Ignarra, Christina M. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)

2014-09-01

Tension among recent short baseline neutrino experiments has pointed toward the possible need for the addition of one or more sterile (non-interacting) neutrino states into the existing neutrino oscillation framework. This thesis first presents the motivation for sterile neutrino models by describing the short-baseline anomalies that can be addressed with them. This is followed by a discussion of the phenomenology of these models. The MiniBooNE experiment and results are then described in detail, particularly the most recent antineutrino analysis. This will be followed by a discussion of global fits to world data, including the anomalous data sets. Lastly, future experiments will be addressed, especially focusing on the MicroBooNE experiment and light collection studies. In particular, understanding the degradation source of TPB, designing the TPB-coated plates for MicroBooNE and developing lightguide collection systems will be discussed. We find an excess of events in the MiniBooNE antineutrino mode results consistent with the LSND anomaly, but one that has a different energy dependence than the low-energy excess reported in neutrino mode. This disagreement creates tension within global fits which include up to three sterile neutrinos. The low-energy excess will be addressed by the MicroBooNE experiment, which is expected to start taking data in early 2015. Tension among existing experiments calls for additional, more decisive future experiments.

Sterile Neutrino Searches in MiniBooNE and MicroBooNE

Energy Technology Data Exchange (ETDEWEB)

Ignarra, Christina M. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)

2014-09-01

Tension among recent short baseline neutrino experiments has pointed toward the possible need for the addition of one or more sterile (non-interacting) neutrino states into the existing neutrino oscillation framework. This thesis fi rst presents the motivation for sterile neutrino models by describing the short-baseline anomalies that can be addressed with them. This is followed by a discussion of the phenomenology of these models. The MiniBooNE experiment and results are then described in detail, particularly the most recent antineutrino analysis. This will be followed by a discussion of global fits to world data, including the anomalous data sets. Lastly, future experiments will be addressed, especially focusing on the MicroBooNE experiment and light collection studies. In particular, understanding the degradation source of TPB, designing the TPB-coated plates for MicroBooNE and developing lightguide collection systems will be discussed. We find an excess of events in the MiniBooNE antineutrino mode results consistent with the LSND anomaly, but one that has a di fferent energy dependence than the low-energy excess reported in neutrino mode. This disagreement creates tension within global fi ts which include up to three sterile neutrinos. The low-energy excess will be addressed by the MicroBooNE experiment, which is expected to start taking data in early 2015. Tension among existing experiments calls for additional, more decisive future experiments.

A method for designing fiberglass sucker-rod strings with API RP 11L

International Nuclear Information System (INIS)

Jennings, J.W.; Laine, R.E.

1991-01-01

This paper presents a method for using the API recommended practice for the design of sucker-rod pumping systems with fiberglass composite rod strings. The API method is useful for obtaining quick, approximate, preliminary design calculations. Equations for calculating all the composite material factors needed in the API calculations are given

IgE-Api m 4 Is Useful for Identifying a Particular Phenotype of Bee Venom Allergy.

Science.gov (United States)

Ruiz, B; Serrano, P; Moreno, C

Different clinical behaviors have been identified in patients allergic to bee venom. Compound-resolved diagnosis could be an appropriate tool for investigating these differences. The aims of this study were to analyze whether specific IgE to Api m 4 (sIgE-Api m 4) can identify a particular kind of bee venom allergy and to describe response to bee venom immunotherapy (bVIT). Prospective study of 31 patients allergic to bee venom who were assigned to phenotype group A (sIgE-Api m 4 Api m 4 ≥0.98 kU/L), treated with purified aqueous (PA) extract. Sex, age, cardiovascular risk, severity of preceding sting reaction, exposure to beekeeping, and immunological data (intradermal test, sIgE/sIgG4-Apis-nApi m 1, and sIgE-rApi m 2-Api m 4 were analyzed. Systemic reactions (SRs) during bVIT build-up were analyzed. Immunological and sting challenge outcomes were evaluated in each group after 1 and 2 years of bVIT. Phenotype B patients had more severe reactions (P=.049) and higher skin sensitivity (P=.011), baseline sIgE-Apis (P=.0004), sIgE-nApi m 1 (P=.0004), and sIgG4-Apis (P=.027) than phenotype A patients. Furthermore, 41% of patients in group B experienced SRs during the build-up phase with NA; the sting challenge success rate in this group was 82%. There were no significant reductions in serial intradermal test results, but an intense reduction in sIgE-nApi m 1 (P=.013) and sIgE-Api m 4 (P=.004) was observed after the first year of bVIT. Use of IgE-Api m 4 as the only discrimination criterion demonstrated differences in bee venom allergy. Further investigation with larger populations is necessary.

Long-Term Temporal Trends of Nosema spp. Infection Prevalence in Northeast Germany: Continuous Spread of Nosema ceranae, an Emerging Pathogen of Honey Bees (Apis mellifera), but No General Replacement of Nosema apis.

Science.gov (United States)

Gisder, Sebastian; Schüler, Vivian; Horchler, Lennart L; Groth, Detlef; Genersch, Elke

2017-01-01

The Western honey bee ( Apis mellifera ) is widely used as commercial pollinator in worldwide agriculture and, therefore, plays an important role in global food security. Among the parasites and pathogens threatening health and survival of honey bees are two species of microsporidia, Nosema apis and Nosema ceranae. Nosema ceranae is considered an emerging pathogen of the Western honey bee. Reports on the spread of N. ceranae suggested that this presumably highly virulent species is replacing its more benign congener N. apis in the global A. mellifera population. We here present a 12 year longitudinal cohort study on the prevalence of N. apis and N. ceranae in Northeast Germany. Between 2005 and 2016, a cohort of about 230 honey bee colonies originating from 23 apiaries was sampled twice a year (spring and autumn) resulting in a total of 5,600 bee samples which were subjected to microscopic and molecular analysis for determining the presence of infections with N. apis or/and N. ceranae . Throughout the entire study period, both N. apis - and N. ceranae -infections could be diagnosed within the cohort. Logistic regression analysis of the prevalence data demonstrated a significant increase of N. ceranae -infections over the last 12 years, both in autumn (reflecting the development during the summer) and in spring (reflecting the development over winter) samples. Cell culture experiments confirmed that N. ceranae has a higher proliferative potential than N. apis at 27° and 33°C potentially explaining the increase in N. ceranae prevalence during summer. In autumn, characterized by generally low infection prevalence, this increase was accompanied by a significant decrease in N. apis -infection prevalence. In contrast, in spring, the season with a higher prevalence of infection, no significant decrease of N. apis infections despite a significant increase in N. ceranae infections could be observed. Therefore, our data do not support a general advantage of N. ceranae over

Investigation into the Manufacture and Properties of Inhalable High-Dose Dry Powders Produced by Comilling API and Lactose with Magnesium Stearate.

Science.gov (United States)

Lau, Michael; Young, Paul M; Traini, Daniela

2017-08-01

The aim of the study was to understand the impact of different concentrations of the additive material, magnesium stearate (MGST), and the active pharmaceutical ingredient (API), respectively, on the physicochemical properties and aerosol performance of comilled formulations for high-dose delivery. Initially, blends of API/lactose with different concentrations of MGST (1-7.5% w/w) were prepared and comilled by the jet-mill apparatus. The optimal concentration of MGST in comilled formulations was investigated, specifically for agglomerate structure and strength, particle size, uniformity of content, surface coverage, and aerosol performance. Secondly, comilled formulations with different API (1-40% w/w) concentrations were prepared and similarly analyzed. Comilled 5% MGST (w/w) formulation resulted in a significant improvement in in vitro aerosol performance due to the reduction in agglomerate size and strength compared to the formulation comilled without MGST. Higher concentrations of MGST (7.5% w/w) led to reduction in aerosol performance likely due to excessive surface coverage of the micronized particles by MGST, which led to failure in uniformity of content and an increase in agglomerate strength and size. Generally, comilled formulations with higher concentrations of API increased the agglomerate strength and size, which subsequently caused a reduction in aerosol performance. High-dose delivery was achieved at API concentration of >20% (w/w). The study provided a platform for the investigation of aerosol performance and physicochemical properties of other API and additive materials in comilled formulations for the emerging field of high-dose delivery by dry powder inhalation.

An overview of the CellML API and its implementation

Directory of Open Access Journals (Sweden)

Halstead Matt

2010-04-01

Full Text Available Abstract Background CellML is an XML based language for representing mathematical models, in a machine-independent form which is suitable for their exchange between different authors, and for archival in a model repository. Allowing for the exchange and archival of models in a computer readable form is a key strategic goal in bioinformatics, because of the associated improvements in scientific record accuracy, the faster iterative process of scientific development, and the ability to combine models into large integrative models. However, for CellML models to be useful, tools which can process them correctly are needed. Due to some of the more complex features present in CellML models, such as imports, developing code ab initio to correctly process models can be an onerous task. For this reason, there is a clear and pressing need for an application programming interface (API, and a good implementation of that API, upon which tools can base their support for CellML. Results We developed an API which allows the information in CellML models to be retrieved and/or modified. We also developed a series of optional extension APIs, for tasks such as simplifying the handling of connections between variables, dealing with physical units, validating models, and translating models into different procedural languages. We have also provided a Free/Open Source implementation of this application programming interface, optimised to achieve good performance. Conclusions Tools have been developed using the API which are mature enough for widespread use. The API has the potential to accelerate the development of additional tools capable of processing CellML, and ultimately lead to an increased level of sharing of mathematical model descriptions.

[Effect of habitat and interspecific competition on Apis cerana cerana colony distribution].

Science.gov (United States)

Yu, Linsheng; Han, Shengming

2003-04-01

Habitat change and interspecific competition were the main factors affecting, Apis cerana cerana colony distribution among Wannan and Wanxi Dabie mountainous areas, Jianghuai area and Huaibei plain. Wannan and Wanxi Dabie mountainous areas were the ideal places for Apis cerana cerana' habitation and propogation, in which, there were integrated natural vegetation, fine ecological condition, abundant nectariferous plants, and Apis cerana cerana had large colony size, wide distribution, high density, no disturbances of natural mating, and was dominant interspecific competition. In Jianghuai area and Huaibei plain, there were small covering of natural vegetation, different degree of degradation of ecological balance, few kinds of nectariferous plants with almost the same blooming periods, natural mating perturbed by Apis mellifera ligustica for Apis cerana cerana, and which was inferior in interspecific competition, colony size sharply decreased, distribution area reduced, and density cut down to a great extent. In Huaibei plain, the negative factors were more conspicuous.

Cross section analyses in MiniBooNE and SciBooNE experiments

OpenAIRE

Katori, Teppei

2013-01-01

The MiniBooNE experiment (2002-2012) and the SciBooNE experiment (2007-2008) are modern high statistics neutrino experiments, and they developed many new ideas in neutrino cross section analyses. In this note, I discuss selected topics of these analyses.

System for Award Management (SAM) API

Data.gov (United States)

General Services Administration — The SAM API is a RESTful method of retrieving public information about the businesses, organizations, or individuals (referred to as entities) within the SAM entity...

Aplicação de análises multivariadas para determinação da casta de abelhas Apis mellifera L. (Africanizadas, obtidas em laboratório Aplication of multivariate analysis for caste determination in Honeybees Apis mellifera L. (Africanized obtained in laboratory conditions

Directory of Open Access Journals (Sweden)

Izabel Christina da Silva

2005-04-01

Full Text Available A técnica de criação de larvas de abelhas Apis mellifera em laboratório tem sido utilizada freqüentemente em estudos de desenvolvimento larval, determinação de castas e, mais recentemente, em testes de patogênese. A quantidade e a qualidade do alimento fornecido às larvas em laboratório podem levar à formação de castas diferentes (rainha, operárias ou intercastas. Neste trabalho, crias de abelhas africanizadas foram desenvolvidas a partir de larvas de 18-24 horas de idade até atingir a fase adulta, utilizando-se durante a alimentação, 4, 15, 25, 50 e 70 µl de dieta por larva, respectivamente, do primeiro ao quinto dia de alimentação. Para determinar se as abelhas adultas obtidas em laboratório eram pertencentes à casta de operárias, de rainhas ou se eram intermediárias (intercastas, foram comparadas com um controle constituído por operárias e rainhas da mesma origem das operárias desenvolvidas no laboratório, utilizando-se o peso e as medidas dos seguintes caracteres: a comprimento da cabeça; b largura da cabeça; c comprimento do olho composto; d largura do olho composto; e comprimento do mesoscuto; f largura do mesoscuto; g comprimento da tíbia; h largura da tíbia. Foram utilizadas a Função Discriminante de Anderson e a técnica de Componentes Principais, de modo a efetuar a discriminação das castas das abelhas adultas obtidas em laboratório em relação àquelas desenvolvidas naturalmente. Entre os caracteres avaliados, os que menos contribuíram para a determinação das castas foram o comprimento do mesoscuto e a largura da cabeça, sendo, portanto, dispensáveis em estudos futuros.Apis mellifera honeybee brood rearing in laboratory conditions has been frequentely used to search for larval development, caste determination, and more recently for tests of pathogenesis. The amount and quality of food received by larvae during the feeding time can produce different castes (queen, worker or intercaste. In the

Caracterização físico-química de amostras de méis de Apis mellifera L. (Hymenoptera: Apidae do Estado do Ceará Physical-chemical characterization of honey samples of Apis mellifera L. (Hymenoptera: Apidae from Ceará State

Directory of Open Access Journals (Sweden)

Geni da Silva Sodré

2007-08-01

Full Text Available Com o objetivo de verificar as características físico-químicas de amostras de méis coletadas em cidades do Estado do Ceará (Araripe, Santana do Cariri, Assaré, Iguatu, Crato, Missão Velha e Pacajús, foram determinados no Laboratório de Apicultura do Departamento de Entomologia, Fitopatologia e Zoologia Agrícola da Escola Superior de Agricultura "Luiz de Queiroz", USP: açúcares totais, açúcares redutores, sacarose aparente, umidade, atividade diastásica, hidroximetilfurfural, proteína, cinzas, pH, acidez, índice de formol, condutividade elétrica, viscosidade e cor de 20 amostras de méis Apis mellifera L., 1758, coletadas entre março de 2002 e agosto de 2002. A maioria das amostras de méis analisadas (65% encontra-se dentro das especificações brasileiras para as características físico-químicas, com exceção das características sacarose aparente (10% das amostras, umidade (10% das amostras, atividade diastásica (35% das amostras e HMF (20% das amostras. Os resultados indicaram condutividade elétrica e a sacarose aparente como as características que mais influenciaram no agrupamento das amostras.This research was aimed at to determining physico-chemical characteristics honey samples collected in cities of Ceara States (Araripe; Santana do Cariri 1 sample; Assaré 1 sample; Iguatu 8 samples; Crato 4 samples; Missão Velha 2 samples and Pacajús 3 samples, they were determined at the laboratory of Apiculture in the "Escola Superior de Agricultura Luiz de Queiroz" (ESALQ University of São Paulo, in Piracicaba, São Paulo State: total sugar, reducing sugars, apparent sucrose, humidity, diastase activity, hydroxymethylfurfural (HMF, protein, ash, pH, acidity, formol index, electrical conductivity, viscosity and color of 20 samples of Apis mellifera L., 1758 honey collected between March of 2002 and August of 2002. Most of the samples of honey analyzed (65% are inside of the Brazilian specifications for the characteristics

Infestação do ácaro Varroa destructor em colônias de abelhas africanizadas (Apis mellifera L. no Semiárido potiguar, Nordeste do Brasil

Directory of Open Access Journals (Sweden)

Stephano Bismark Lopes Cavalcante Moreira

2017-02-01

Full Text Available O presente trabalho teve como objetivo analisar os índices de infestação pelo ácaro Varroa. destructor em colônias de abelhas africanizadas (Apis mellifera de apiários dos municípios de Encanto e de Marcelino Vieira, estado do Rio Grande do Norte. A pesquisa foi conduzida no período de setembro a dezembro de 2014, sendo coletadas em média de 100 a 200 abelhas adultas (nutrizes retiradas dos quadros centrais do ninho com crias de cada colmeia, aprisionadas em recipientes contendo 100 mL de álcool a 70% e encaminhadas para laboratório do Instituto Federal do Rio Grande do Norte (IFRN, para a contagem das abelhas e dos ácaros. Os resultados apresentaram ocorrência do ácaro V. destructor em todos apiários e em todas colmeias analisados, obtendo uma infestação média de 7,24% em Encanto e de 5,25% em Marcelino Vieira, níveis de infestação baixos (<15%, portanto, não acarretando risco às colônias.Varroa destructor mite infestation in colonies of Africanized honey bees (Apis mellifera L. in the potiguar Semi-arid region, Northeastern BrazilAbstract: The goal of the present work was to analyze the rates of infestation by Varroa. destructor mite in Africanized honeybees (Apis mellifera colonies from apiaries in Encanto and Marcelino Vieira cities, state of Rio Grande do Norte. The research was conducted during the period from September to December 2014. In average 100 to 200 adult bees (nursing honey bee workers were collected from the brood chamber over center frames of with brood of each hive surveyed, trapped in containers containing 100 mL of 70% alcohol and sent to the laboratory of the Federal Institute of Rio Grande do Norte (IFRN for the counting of bees and mites. The results showed an occurrence of the Varroa destructor mite in all apiaries and in all hives analyzed, obtaining an average infestation of 7.24% in Encanto city and 5.25% in Marcelino Vieira city, low infestation levels (<15%, without risk to the colonies.

Taxa de Infestação da Varroa destructor em colônias de Apis mellifera L. no Agreste Meridional de Pernambuco

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Deygnon Cavalcanti Clementino

2016-08-01

Full Text Available O presente trabalho teve como objetivo verificar a taxa de infestação da Varroa destructor em colônias de Apis mellifera L. proveniente de apiário no município de Lagoa do Ouro, Agreste Meridional de Pernambuco. A pesquisa foi realizada no mês de setembro de 2015. Participaram do estudo 15 colônias, em que foram coletadas em média 227 abelhas adultas de cada colmeia e acondicionadas em recipientes contendo álcool a 70%. Após as coletas a campo, as amostras foram transportadas para o laboratório de Biologia Animal da Universidade Federal Rural de Pernambuco/Unidade Acadêmica de Garanhuns, para a realização das análises e quantificação dos ácaros. Os resultados demonstraram que 100% das amostras estavam parasitadas com o ácaro, sendo que a média geral da taxa de infestação foi de 6,16%. O grau de infestação pela Varroa destructor observado nas colônias variou de 0,93% a 11,15%. Conclui-se que as colônias analisadas apresentam diferentes níveis de infestação pelo ácaro Varroa destructor.Infestation rate of Varroa destructor in Apis mellifera L. colonies in the South Agreste of PernambucoAbstract: This study aimed to verify the infestation rate of Varroa destructor in Apis mellifera L. colonies in the apiary from Lagoa do Ouro County, South Agreste of Pernambuco. The survey was conducted in September 2015. The study included 15 colonies, which were collected on average 227 adult bees in each hive and placed in vials containing 70% alcohol. After harvesting the field, the samples were transported to the Animal Biology Laboratory at the Federal Rural University of Pernambuco/Academic Unit of Garanhuns, to perform the analysis and quantification of mites. The results showed that 100% of the samples were infested with mites, and the overall average infestation rate was 6.16%. The degree of infestation by Varroa destructor observed in colonies ranged from 0.93% to 11.15%. It is concluded that the analyzed colonies have

Predominant Api m 10 sensitization as risk factor for treatment failure in honey bee venom immunotherapy.

Science.gov (United States)

Frick, Marcel; Fischer, Jörg; Helbling, Arthur; Ruëff, Franziska; Wieczorek, Dorothea; Ollert, Markus; Pfützner, Wolfgang; Müller, Sabine; Huss-Marp, Johannes; Dorn, Britta; Biedermann, Tilo; Lidholm, Jonas; Ruecker, Gerta; Bantleon, Frank; Miehe, Michaela; Spillner, Edzard; Jakob, Thilo

2016-12-01

Component resolution recently identified distinct sensitization profiles in honey bee venom (HBV) allergy, some of which were dominated by specific IgE to Api m 3 and/or Api m 10, which have been reported to be underrepresented in therapeutic HBV preparations. We performed a retrospective analysis of component-resolved sensitization profiles in HBV-allergic patients and association with treatment outcome. HBV-allergic patients who had undergone controlled honey bee sting challenge after at least 6 months of HBV immunotherapy (n = 115) were included and classified as responder (n = 79) or treatment failure (n = 36) on the basis of absence or presence of systemic allergic reactions upon sting challenge. IgE reactivity to a panel of HBV allergens was analyzed in sera obtained before immunotherapy and before sting challenge. No differences were observed between responders and nonresponders regarding levels of IgE sensitization to Api m 1, Api m 2, Api m 3, and Api m 5. In contrast, Api m 10 specific IgE was moderately but significantly increased in nonresponders. Predominant Api m 10 sensitization (>50% of specific IgE to HBV) was the best discriminator (specificity, 95%; sensitivity, 25%) with an odds ratio of 8.444 (2.127-33.53; P = .0013) for treatment failure. Some but not all therapeutic HBV preparations displayed a lack of Api m 10, whereas Api m 1 and Api m 3 immunoreactivity was comparable to that of crude HBV. In line with this, significant Api m 10 sIgG 4 induction was observed only in those patients who were treated with HBV in which Api m 10 was detectable. Component-resolved sensitization profiles in HBV allergy suggest predominant IgE sensitization to Api m 10 as a risk factor for treatment failure in HBV immunotherapy. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

Agnostic stacking of intergalactic doublet absorption: measuring the Ne VIII population

Science.gov (United States)

Frank, Stephan; Pieri, Matthew M.; Mathur, Smita; Danforth, Charles W.; Shull, J. Michael

2018-05-01

We present a blind search for doublet intergalactic metal absorption with a method dubbed `agnostic stacking'. Using a forward-modelling framework, we combine this with direct detections in the literature to measure the overall metal population. We apply this novel approach to the search for Ne VIII absorption in a set of 26 high-quality COS spectra. We probe to an unprecedented low limit of log N>12.3 at 0.47≤z ≤1.34 over a path-length Δz = 7.36. This method selects apparent absorption without requiring knowledge of its source. Stacking this mixed population dilutes doublet features in composite spectra in a deterministic manner, allowing us to measure the proportion corresponding to Ne VIII absorption. We stack potential Ne VIII absorption in two regimes: absorption too weak to be significant in direct line studies (12.3 13.7). We do not detect Ne VIII absorption in either regime. Combining our measurements with direct detections, we find that the Ne VIII population is reproduced with a power-law column density distribution function with slope β = -1.86 ^{+0.18 }_{ -0.26} and normalization log f_{13.7} = -13.99 ^{+0.20 }_{ -0.23}, leading to an incidence rate of strong Ne VIII absorbers dn/dz =1.38 ^{+0.97 }_{ -0.82}. We infer a cosmic mass density for Ne VIII gas with 12.3 value significantly lower that than predicted by recent simulations. We translate this density into an estimate of the baryon density Ωb ≈ 1.8 × 10-3, constituting 4 per cent of the total baryonic mass.

Produtos naturais no comportamento defensivo de Apis mellifera L. - doi: 10.4025/actascianimsci.v32i3.8486 Natural products in the defensive behaviour of Apis mellifera L. - doi: 10.4025/actascianimsci.v32i3.8486

Directory of Open Access Journals (Sweden)

Silvia Maria Alves Gomes

2010-09-01

Full Text Available Os objetivos do estudo foram investigar a influência de produtos naturais como capim-limão (Cymbopogon citratus, folhas de abacateiro (Persea americana, casca de café (Coffea arabica e sementes de mamona (Ricinus communis na defensividade de Apis mellifera, e avaliar o efeito destes produtos no desenvolvimento populacional da colmeia. O comportamento defensivo foi avaliado por meio do tempo da primeira ferroada (TPF, número de ferrões (NFB e, o desenvolvimento populacional, pela área de cria aberta e fechada. Observou-se que o tratamento fumaça + sete sementes de mamona apresentou aumento significativo no TPF, em relação ao tratamento sem e com fumaça de maravalha. Com relação ao NFB, verificou-se que os tratamentos fumaça de maravalha + sete sementes de mamona e fumaça de maravalha + 20% de folhas de café foram diferentes do tratamento sem e com fumaça. Os demais tratamentos não diferiram significativamente em relação ao uso da fumaça ou sua ausência. A casca de café e a semente de mamona não interferiram no desenvolvimento populacional, sugerindo que estes compostos não foram tóxicos. Pode-se concluir que o uso de sementes de mamona e casca de café na fumaça pode representar importante ferramenta para a redução da defensividade, sem promover toxicidade para A. mellifera.The goal was to investigate the influence of natural products such as lemongrass (Cymbopogon citratus, dried avocado leaves (Persea americana, coffee husk (Coffea arabica and castor bean (Ricinus communis in the defense of Apis mellifera, as well the effect of these products on the population development of the beehive. Defensive behavior was evaluated by time of first sting (TFS and number of stingers (NS, and population development, by open brood area and operculated brood. It was observed that the treatment with smoke + seven castor beans presented significant increase in the TFS, for treatment without and with smoke. Regarding NS, it was

Surface acidity and solid-state compatibility of excipients with an acid-sensitive API: case study of atorvastatin calcium.

Science.gov (United States)

Govindarajan, Ramprakash; Landis, Margaret; Hancock, Bruno; Gatlin, Larry A; Suryanarayanan, Raj; Shalaev, Evgenyi Y

2015-04-01

The objectives of this study were to measure the apparent surface acidity of common excipients and to correlate the acidity with the chemical stability of an acid-sensitive active pharmaceutical ingredient (API) in binary API-excipient powder mixtures. The acidity of 26 solid excipients was determined by two methods, (i) by measuring the pH of their suspensions or solutions and (ii) the pH equivalent (pHeq) measured via ionization of probe molecules deposited on the surface of the excipients. The chemical stability of an API, atorvastatin calcium (AC), in mixtures with the excipients was evaluated by monitoring the appearance of an acid-induced degradant, atorvastatin lactone, under accelerated storage conditions. The extent of lactone formation in AC-excipient mixtures was presented as a function of either solution/suspension pH or pHeq. No lactone formation was observed in mixtures with excipients having pHeq > 6, while the lactone levels were pronounced (> 0.6% after 6 weeks at 50°C/20% RH) with excipients exhibiting pHeq 6, 3-6, and < 3) were consistent with the reported solution pH-stability profile of AC. In contrast to the pHeq scale, lactone formation did not show any clear trend when plotted as a function of the suspension/solution pH. Two mechanisms to explain the discrepancy between the suspension/solution pH and the chemical stability data were discussed. Acidic excipients, which are expected to be incompatible with an acid-sensitive API, were identified based on pHeq measurements. The incompatibility prediction was confirmed in the chemical stability tests using AC as an example of an acid-sensitive API.

Web 2.0 y herramientas en red para Educación Infantil y Primaria

OpenAIRE

Solano Fernández, Isabel Mª

2010-01-01

Documento sobre Web 2.0 y herramientas y recursos para Eduación Infantil y Primaria, en el que se hace un recorrido por los términos Web 1.0, Web 2.0 y Web 3.0, y se presentan diversos recursos a partir de diferentes categorías: en función de las variables espacio-temporales, del sistema simbólico y la función. Ejercicios prácticos

JASPAR RESTful API: accessing JASPAR data from any programming language.

Science.gov (United States)

Khan, Aziz; Mathelier, Anthony

2018-05-01

JASPAR is a widely used open-access database of curated, non-redundant transcription factor binding profiles. Currently, data from JASPAR can be retrieved as flat files or by using programming language-specific interfaces. Here, we present a programming language-independent application programming interface (API) to access JASPAR data using the Representational State Transfer (REST) architecture. The REST API enables programmatic access to JASPAR by most programming languages and returns data in eight widely used formats. Several endpoints are available to access the data and an endpoint is available to infer the TF binding profile(s) likely bound by a given DNA binding domain protein sequence. Additionally, it provides an interactive browsable interface for bioinformatics tool developers. This REST API is implemented in Python using the Django REST Framework. It is accessible at http://jaspar.genereg.net/api/ and the source code is freely available at https://bitbucket.org/CBGR/jaspar under GPL v3 license. aziz.khan@ncmm.uio.no or anthony.mathelier@ncmm.uio.no. Supplementary data are available at Bioinformatics online.

API manager implementation and its use for Indus accelerator control

International Nuclear Information System (INIS)

Merh, B.N.; Agrawal, R.K.; Barpande, K.; Fatnani, P.; Navathe, C.P.

2012-01-01

The control system software needed for operation of Indus accelerators is coupled to the underlying firmware and hardware of the control system by the Application Programming Interface (API) manager. In the three layered architecture of Indus control system, PVSS-II SCADA is being used at the layer-1(L1) for control and monitoring of various sub-systems. The layer-2(L2) consists of VME bus based system. The API manager plays a crucial role in interfacing the L1 and L2 of the control system. It has to interact with both the PVSS database and the L2. In order to access the PVSS database it uses the PVSS API, a C++ class library, whereas in order to access the L2 custom functions have been built. Several other custom functionalities have also been implemented. The paper presents the important aspects of the API manager like its implementation, its interface mechanism to the lower layer and features like configurability, reusable classes, multithreading capability etc. (author)

Technological properties of kaolin from Para; Propriedades tecnologicas do caulin do Para

Energy Technology Data Exchange (ETDEWEB)

Hildebrando, E.; Martin-Cortes, G.R.; Esper, F.J.; Wiebeck, H.; Alves Junior, P.; Valenzuela-Diaz, F.R., E-mail: germac@usp.br [Universidade de Sao Paulo (PMT/EP/USP), Sao Paulo, SP (Brazil). Escola Politecnica. Departamento de Engenharia Metalurgica e de Materiais

2011-07-01

The NE of the State of Para, is notable for its large reserves of kaolin for paper. Kaolin is a mineral composed of hydrated aluminum silicates such as kaolinite and halloysite. The exploitation of these reserves to generate products with higher commercial value, especially in the industries of adsorbents and catalysts, is what motivates the continuous study of technological properties of the Amazon kaolin's. Thus, this paper presents a technological characterization of a sample of kaolin from Para State by X-ray diffraction, SEM - scanning electron microscopy and infrared spectroscopy. The results of preliminary tests indicate that the sample consists for the most part by kaolinite present in low concentrations of quartz and anatase. (author)

Disseny i desenvolupament d'una aplicació Andriod "CercaJam"

OpenAIRE

Puig Orpinell, Edgard

2013-01-01

El projecte vol desenvolupar un programari per Android destinat als usuaris que els interessin les jam sessions. El programa sera capaç de visualitzar les sales, cercar-les per nom o ciutat i afegir-ne una de nova. L'idea principal és que l'usuari pugui inscriure's, si queden places lliures, a la jam session de la sala. On també podrà ubicar-la, mitjançant l'API de Google Maps. El proyecto quiere desarrollar un software para Android destinado a los usuarios que les interesen las jam sessio...

Equilibration in the reaction of 175 and 252 MeV 20Ne with 197Au

International Nuclear Information System (INIS)

Moulton, J.B.

1978-06-01

The highly inelastic nuclear reaction of 197 Au with 20 Ne at 175 and 252 MeV laboratory energies is studied. Energy-, elemental-, and angular- distributions for atomic numbers 5 to 30 (175 MeV) or 34 (252 MeV) are presented. The means and widths of the kinetic energy spectra for detected elements are compared with a theoretical calculation. The calculation postulates thermalization of the incident projectile kinetic energy, and includes one sha(e-vibrational degree of freedom and rigid rotation of the reaction complex. The effect of particle evaporation is considered. Good agreement of the expurimental mean energies with the theory is obtained. Poorer agreement of the kinetic energy widths with the theory may be due to a low-temperature quantal effect. The relative elemental yields are analyzed for their degree of equilibration, based on a model of diffusive nucleon exchange as described by the master equation. A similar degree of equilibration is observed for both reaction energies. The absolute elemental yields are reproduced qualitatively by employing an advanced diffusion code, coupled with calculation of the subsequent fission of heavy reaction products, including the compound nucleus. The angular distributions are analyzed with a simple model, to estimate the reaction lifetime of selected elements

Fusion dynamics of 2020Ne + 20882Pb reaction using static and energy dependent Woods-Saxon potential

International Nuclear Information System (INIS)

Gautam, Manjeet Singh; Kaur, Amandeep; Sharma, Manoj K.

2015-01-01

The present work compares the theoretical predictions based on static Woods-Saxon potential and the EDWSP model along with one dimensional Wong formula. For 20 20 Ne + 208 82 Pb reaction, the theoretical calculations obtained by using static Woods-Saxon potential are substantially smaller than that of experimental data at below barrier energies and explain the fusion data at above barrier energies only. On the other hand, the EDWSP model based calculations adequately describe the observed fusion enhancement of 20 20 Ne + 208 82 Pb reaction in whole range of energy spread across the Coulomb barrier. Furthermore, a wide range of the diffuseness parameter ranging from 0.96 fm to 0.85 fm is required to address the sub-barrier fusion data

Induction bending of API 5L X80 pipes; Curvamento a quente de tubos API 5L X80

Energy Technology Data Exchange (ETDEWEB)

Batista, Gilmar Z. [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil)]. E-mail: g.zacca@petrobras.com.br; Naschpitz, Leonardo [Primus Processamento de Tubos S.A. - PROTUBO, Campo Grande, RJ (Brazil)]. E-mail: naschpitz@protubo.com.br

2005-07-01

The present work is a part of an extensive program to make possible the application of API 5L X80 in pipeline construction in Brazil. At this stage, the effect of the induction bending process on the microstructure and mechanical properties of the pipe is presented. For this study an API 5L X80 pipe, made by the UOE process, is used. The pipe was manufactured from a plate produced by thermo-mechanically controlled rolling without accelerated cooling. The pipe bending was carried out applying a local induction heating following by water quenching. The bend section, outer and inner curvature regions, of the pipe bend were evaluated and compared with the original pipe. The longitudinal weld and transition zones were not evaluated at this stage. Dimensional analyses, microstructural evaluation, Charpy-V impact tests, and tensile tests were performed. A significant microstructural change was verified in the bend area. The yield strength of the pipe bend was found to be lower than original pipe and standard requirements. Other tensile properties and impact properties are compatible with API 5L X80 requirements. (author)

Application of Skype API to Control Working Time

Directory of Open Access Journals (Sweden)

Julian Vasilev

2013-11-01

Full Text Available The purpose of this article is to present an innovative approach to monitor and control working time. A special software program is developed by Delphi implementing Skype API functions. This article shows three different approaches to control working time using the Skype_API program. It automatically detects when an employee goes to his working place and when he leaves work. Moreover it can check periodically weather an employee is at work. The proposed ideas are written for the first time. They may be applied easily in many enterprises with very low costs.

Hélène Mialet, Hawking Incorporated. Stephen Hawking and the Anthropology of the Knowing subject

OpenAIRE

Popescu, Cristina

2013-01-01

Situé dans la tradition de recherche développée autour de la théorie de l’acteur-réseau (actor-network theory), le livre de Hélène Mialet choisit d’explorer la figure particulière du physicien anglais Stephen Hawking. À travers sept chapitres complémentaires, le lecteur découvre à la fois « Hawking l’individu » et « Hawking le génie en physique ». C’est une distinction qui ne paraît pas toute de suite évidente au non-initié, mais, nous allons le comprendre rapidement, le Hawking des médias, n...

Produção e desenvolvimento de colônias de abelhas africanizadas (Apis mellifera l. a partir de diferentes áreas e idades de cria Production and development of africanized honey bee (Apis mellifera l. colonies departing from different comb brood areas and brood ages

Directory of Open Access Journals (Sweden)

Roberto Henrique Dias da Silva

2004-04-01

Full Text Available A apicultura brasileira usa da captura de enxames silvestres de abelhas melíferas africanizadas (Apis mellifera L. para repor e/ou aumentar o número de colônias dos apiários, possuindo inconvenientes como a dependência da natureza para captura dos enxames, a heterogeneidade genética das colônias capturadas e a possibilidade desses enxames serem portadores de doenças e parasitas prejudiciais à sanidade das abelhas. O presente trabalho testa e apresenta uma técnica de divisão de colônias de abelhas melíferas africanizadas para a produção de novas colônias fortes em curto espaço de tempo, a partir de recursos mínimos de cera, cria e alimento. Os resultados mostraram que núcleos de A. mellifera formados inicialmente com uma rainha jovem e fecundada, 1 kg de operárias, um quadro de cria fechada, um quadro de favo puxado e vazio e dois quadros com cera alveolada permitem a produção de novas colônias em 42 dias. Portanto, pode-se concluir que a técnica de divisão de colônias por formação de núcleos como descrito acima, oferece aos apicultores uma alternativa viável para a produção e comercialização em larga escala de novas colônias de abelhas melíferas africanizadas.The Brazilian apiculture relies upon collecting wild swarms of Africanized honey bees (Apis mellifera L. to replace and/or increase the number of colonies in the apiaries. This practice brings problems such as dependence on nature to capture any swarm, diverse genetic make-up of the colonies captured and the possibility of these swarms be carrying diseases and parasites harmful to the bees. The present work tests and presents a technique to split colonies of Africanized honey bees to produce new strong colonies in short time, departing from little resources of wax, brood and food stores. Results showed that A. mellifera nuclei formed by a young and mated queen, 1kg of workers, a frame of sealed brood, an empty frame of drawn beeswax and two frames

Fusion-fission and deep inelastic orbiting in the target-like yields from 32S formed in 20Ne+12C reaction at different excitation energies

International Nuclear Information System (INIS)

Singh, BirBikram; Kaur, Mandeep; Sharma, Manoj K.; Gupta, Raj K.

2014-01-01

A strong motivation behind this work is that, though NOC model marked large σ C Expt in the decay of 32 S or small NOC for 20 Ne+ 12 C reaction indicating equivalently possibility of nCN contribution in it, but it does not work out the amount of contributions of σ ff and σ orb separately in the total σ C and the dynamics behind it, at different centre of mass energies, E c.m. . We intend to address this question in the present work

A Shellcode Detection Method Based on Full Native API Sequence and Support Vector Machine

Science.gov (United States)

Cheng, Yixuan; Fan, Wenqing; Huang, Wei; An, Jing

2017-09-01

Dynamic monitoring the behavior of a program is widely used to discriminate between benign program and malware. It is usually based on the dynamic characteristics of a program, such as API call sequence or API call frequency to judge. The key innovation of this paper is to consider the full Native API sequence and use the support vector machine to detect the shellcode. We also use the Markov chain to extract and digitize Native API sequence features. Our experimental results show that the method proposed in this paper has high accuracy and low detection rate.

Physics at DAΦNE

International Nuclear Information System (INIS)

Franzini, P.J.

1995-01-01

In this talk, I will give a brief description of the φ factory DAΦNE at Frascati, explaining why a φ factory is an interesting place to do new physics, and then discuss the physics that can be done at DAΦNE. I will concentrate on CP violation as it can be studied at DAΦNE. This is, after all, the raison d'etre of DAΦNE. I start with a brief general introduction to CP violation in the KK system, and the distinction between mass-mixing CP violation (ε) and intrinsic CP violation (ε'/ε). After presenting a summary of ε'/ε measurements up to now, and briefly discussing the theory of ε'/ε (the so-called 'penguins'), I will cover the particularities of measuring ε'/ε at a φ factory, such as tagging and interferometry. Finally, I will say a few words about searching for CP violation in modes where it has never before been seen. I will end my talk with a list of other physics topics at DAΦNE, and rare decay branching ratio limits that can be achieved there, just to give a flavor of what else can be done. (author) 8 figs., 2 tabs., 22 refs

MicroBooNE: The Search For The MiniBooNE Low Energy Excess

Energy Technology Data Exchange (ETDEWEB)

Kaleko, David [Columbia Univ., New York, NY (United States)

2017-01-01

This thesis describes work towards the search for a low energy excess in MicroBooNE. What MicroBooNE is, what the low energy excess is, and how one searches for the latter in the former will be described in detail.

A satellite view of riverine turbidity plumes on the NE-E Brazilian coastal zone

Directory of Open Access Journals (Sweden)

Eduardo Negri de Oliveira

2012-09-01

Full Text Available Turbidity plumes of São Francisco, Caravelas, Doce, and Paraiba do Sul river systems, located along the NE/E Brazilian coast, are analyzed for their dispersal patterns of Total Suspended Solids (TSS concentration using Landsat images and a logarithmic algorithm proposed by Tassan (1987 to convert satellite reflectance values to TSS. The TSS results obtained were compared to in situ collected TSS data. The analysis of the satellite image data set revealed that each river system exhibits a distinct turbidity plume dispersal pattern. The behavior, dimension and degree of turbidity of the São Francisco River plume have been greatly altered by the construction of a cascade of hydroelectric dam reservoirs in its hydrological basin. The plume has lost its typical unimodal seasonal pattern of material dispersion and its turbidity has decreased due to the regulation of river flow by the dams and TSS retainance by the reservoirs. In contrast, the Doce and Paraíba do Sul river plumes are still subject to seasonal pulsations and show more turbid conditions than the SF plume, as dams are less numerous, set in the middle river sections and the natural river flow has been maintained. The Caravelas Coastal System river plume is restricted to near shore shallow waters dominated by resuspension processes. During austral spring and summer when NE-E winds prevail, all plumes generally disperse southward. Short-term northward reversals may occur in winter with the passage of atmospheric cold fronts. The São Francisco and Doce river plumes tend to disperse obliquely to the coast and transport materials further offshore, while the Caravelas and Paraíba do Sul plumes tend to disperse mainly parallel to the coast, enhancing TSS retention nearshore.O presente estudo analisa as plumas de turbidez dos sistemas dos rios São Francisco, Caravelas, Doce, e Paraiba do Sul localizados na costa NE/E do Brasil utilizando imagens Landsat e o algoritmo logarítmico para Total

Novel diagnostic tools for Asian (Apis cerana) and European (Apis mellifera) honey authentication.

Science.gov (United States)

Soares, Sónia; Grazina, Liliana; Mafra, Isabel; Costa, Joana; Pinto, M Alice; Duc, Hanh Pham; Oliveira, M Beatriz P P; Amaral, Joana S

2018-03-01

Honey can be produced by different species of honeybees, with two being of economic importance due to their use in apiculture, namely Apis mellifera (known as European honeybee) and Apis cerana (known as Asian honeybee). Due to the decline of the wild populations of the Asian honeybee, this honey generally attains much higher market value, being prone to adulteration. This work aims at proposing new tools, based on the use of molecular markers, for the entomological authentication of honey. To this end, new species-specific primers were designed targeting the tRNA leu -cox2 intergenic region and allowing the detection of A. cerana DNA by qualitative polymerase chain reaction (PCR). Additionally, a novel real-time PCR method with high resolution melting analysis was developed to target the 16S rRNA gene of both bee species, allowing their discrimination in different clusters. The proposed methodologies were further applied with success in the authentication of Asian and European honey samples by the identification of honeybee DNA, demonstrating the usefulness of these simple and cost-effective new approaches. Copyright © 2017 Elsevier Ltd. All rights reserved.

Oscillatory behaviour of Rydberg state total cross sections in the collisions Ne+-He and He+-Ne

International Nuclear Information System (INIS)

Andresen, B.; Jensen, K.; Veje, E.

1976-01-01

The Ne + -He and He + -Ne collisions have been studied by means of optical spectrometry in the projectile energy range 10-150 keV. Very similar and regular oscillations in the Rydberg state total cross sections are found for HeI in both collisions and for singlet as well as triplet excitation. These oscillations are well described by the Rosenthal model. The HeI 4d sup(1,3)D states display two superimposed oscillations for center-of-mass collision energies above 6.4 keV. This is interpreted as the opening of a third exit channel, believed to be the HeI 4f sup(1,3)F. No, or very little structure is found in the Rydberg state total cross sections for HeII, NeI, NeII and NeIII levels. (Auth.)

A New Metazoan Recombination Rate Record and Consistently High Recombination Rates in the Honey Bee Genus Apis Accompanied by Frequent Inversions but Not Translocations

Science.gov (United States)

Kuster, Ryan; Miller, Katelyn; Fouks, Bertrand; Rubio Correa, Sara; Collazo, Juan; Phaincharoen, Mananya; Tingek, Salim; Koeniger, Nikolaus

2016-01-01

Abstract Western honey bees (Apis mellifera) far exceed the commonly observed 1–2 meiotic recombination events per chromosome and exhibit the highest Metazoan recombination rate (20 cM/Mb) described thus far. However, the reasons for this exceptional rate of recombination are not sufficiently understood. In a comparative study, we report on the newly constructed genomic linkage maps of Apis florea and Apis dorsata that represent the two honey bee lineages without recombination rate estimates so far. Each linkage map was generated de novo, based on SNP genotypes of haploid male offspring of a single female. The A. florea map spans 4,782 cM with 1,279 markers in 16 linkage groups. The A. dorsata map is 5,762 cM long and contains 1,189 markers in 16 linkage groups. Respectively, these map sizes result in average recombination rate estimates of 20.8 and 25.1 cM/Mb. Synteny analyses indicate that frequent intra-chromosomal rearrangements but no translocations among chromosomes accompany the high rates of recombination during the independent evolution of the three major honey bee lineages. Our results imply a common cause for the evolution of very high recombination rates in Apis. Our findings also suggest that frequent homologous recombination during meiosis might increase ectopic recombination and rearrangements within but not between chromosomes. It remains to be investigated whether the resulting inversions may have been important in the evolutionary differentiation between honey bee species. PMID:28173114

Neutrino Interactions in MicroBooNE

OpenAIRE

Del Tutto, Marco

2017-01-01

MicroBooNE is a liquid-argon-based neutrino experiment, which began collecting data in Fermilab's Booster neutrino beam in October 2015. Physics goals of the experiment include probing the source of the anomalous excess of electron-like events in MiniBooNE. In addition to this, MicroBooNE is carrying out an extensive cross section physics program that will help to probe current theories on neutrino-nucleon interactions and nuclear effects. These proceedings summarise the status of MicroBooNE'...

Ion mobilities in Xe/Ne and other rare-gas mixtures

Energy Technology Data Exchange (ETDEWEB)

Piscitelli, D; Pitchford, L C [Centre de Physique des Plasmas et Applications de Toulouse (CPAT), UMR 5002 CNRS, 118 route de Narbonne, 31062 Toulouse (France); Phelps, A V [JILA, University of Colorado and National Institute of Technology, Boulder, Colorado (United States); Urquijo, J de [Centro de Ciencias Fisicas, Universidad Nacional Autonoma de Mexico, Post Office Box 48-3, 62251, 80309-0440 Cuernavaca, Moreno (Mexico); Basurto, E [Departmento de Ciencias Basicas, Universidad Autonoma Metropolitana, 02200 Mexico Distrito Federal (Mexico)

2003-10-01

The ion mobility or drift velocity data important for modeling glow discharges in rare gas mixtures are not generally available, nor are the ion-neutral scattering cross sections needed to calculate these data. In this paper we propose a set of cross sections for Xe{sup +} and Ne{sup +} collisions with Xe and Ne atoms. Ion mobilities at 300 K calculated using this cross section set in a Monte Carlo simulation are reported for reduced field strengths, E/N, up to 1500x10{sup -21} V m{sup 2}, in pure gases and in Xe/Ne mixtures containing 5% and 20% Xe/Ne, which are mixtures of interest for plasma display panels (PDPs). The calculated Xe{sup +} mobilities depend strongly on the mixture composition, but the Ne{sup +} mobility varies only slightly with increasing Xe in the mixture over the range studied here. The mobilities in pure gases compare well with available experimental values, and mobilities in gas mixtures at low E/N compare well with our recent measurements which will be published separately. Results from these calculations of ion mobilities are used to evaluate the predictions of Blanc's law and of the mixture rule proposed by Mason and Hahn [Phys. Rev. A 5, 438 (1972)] for determining the ion mobilities in mixtures from a knowledge of the mobilities in each of the pure gases. The mixture rule of Mason and Hahn is accurate to better than 10% at high field strengths over a wide range of conditions of interest for modeling PDPs. We conclude that a good estimate of ion mobilities at high E/N in Xe/Ne and other binary rare gas mixtures can be obtained using this mixture rule combined with known values of mobilities in parent gases and with the Langevin form for mobility of rare gas ions ion in other gases. This conclusion is supported by results in Ar/Ne mixtures which are also presented here.

Restaurant closure for the Jeûne genevois

CERN Multimedia

2007-01-01

Restaurant 1 will be closed on Thursday 6th September (Jeûne Genevois) as well as Friday 7th, Saturday 8th and Sunday 9th September for technical reasons. During this time, Restaurant 2 will be open at the following times: –\tThursday 6th September: 9:00 – 20:00 –\tFriday 7th September: 8:00 – 20:00 –\tSaturday 8th and Sunday 9th September: 9:00–20:00 Hot meals will be served on all 4 days from 12:00 to 14:00 and from 18:00 to 19:30. For more information please see http://cern.ch/restaurant2 Thank you for your understanding.

A SNP based high-density linkage map of Apis cerana reveals a high recombination rate similar to Apis mellifera.

Directory of Open Access Journals (Sweden)

Yuan Yuan Shi

Full Text Available BACKGROUND: The Eastern honey bee, Apis cerana Fabricius, is distributed in southern and eastern Asia, from India and China to Korea and Japan and southeast to the Moluccas. This species is also widely kept for honey production besides Apis mellifera. Apis cerana is also a model organism for studying social behavior, caste determination, mating biology, sexual selection, and host-parasite interactions. Few resources are available for molecular research in this species, and a linkage map was never constructed. A linkage map is a prerequisite for quantitative trait loci mapping and for analyzing genome structure. We used the Chinese honey bee, Apis cerana cerana to construct the first linkage map in the Eastern honey bee. RESULTS: F2 workers (N = 103 were genotyped for 126,990 single nucleotide polymorphisms (SNPs. After filtering low quality and those not passing the Mendel test, we obtained 3,000 SNPs, 1,535 of these were informative and used to construct a linkage map. The preliminary map contains 19 linkage groups, we then mapped the 19 linkage groups to 16 chromosomes by comparing the markers to the genome of A. mellfiera. The final map contains 16 linkage groups with a total of 1,535 markers. The total genetic distance is 3,942.7 centimorgans (cM with the largest linkage group (180 loci measuring 574.5 cM. Average marker interval for all markers across the 16 linkage groups is 2.6 cM. CONCLUSION: We constructed a high density linkage map for A. c. cerana with 1,535 markers. Because the map is based on SNP markers, it will enable easier and faster genotyping assays than randomly amplified polymorphic DNA or microsatellite based maps used in A. mellifera.

Real World Uses For Nagios APIs

Science.gov (United States)

Singh, Janice

2014-01-01

This presentation describes the Nagios 4 APIs and how the NASA Advanced Supercomputing at Ames Research Center is employing them to upgrade its graphical status display (the HUD) and explain why it's worth trying to use them yourselves.

An improved method for interpreting API filter press hydraulic conductivity test results

International Nuclear Information System (INIS)

Heslin, G.M.; Baxter, D.Y.; Filz, G.M.; Davidson, R.R.

1997-01-01

The American Petroleum Institute (API) filter press is frequently used to measure the hydraulic conductivity of soil-bentonite backfill during the mix design process and as part of construction quality controls. However, interpretation of the test results is complicated by the fact that the seepage-induced consolidation pressure varies from zero at the top of the specimen to a maximum value at the bottom of the specimen. An analytical solution is available which relates the stress, compressibility, and hydraulic conductivity in soil consolidated by seepage forces. This paper presents the results of a laboratory investigation undertaken to support application of this theory to API hydraulic conductivity tests. When the API test results are interpreted using seepage consolidation theory, they are in good agreement with the results of consolidometer permeameter tests. Limitations of the API test are also discussed

New constraint of clustering for AMD and its application to the study of the 2α-12C structure of 20Ne

International Nuclear Information System (INIS)

Taniguchi, Yasutaka; Horiuchi, Hisashi; Kimura, Masaaki

2004-01-01

A new constraint of clustering for the AMD calculation is proposed. This constraint yield a significant improvement in the investigation of the cluster structure using AMD, which sometimes meets with difficulty in producing certain specific cluster configuration. The usefulness of this constraint is verified by applying it to the study of the K π = 0 3 + band of 20 Ne, which has been conjectured to have 2α- 12 C structure. This band is not easy to construct with AMD. We show that the constraint in the AMD + GCM calculation is effective for the purpose of obtaining the K π 0 3 + band, which contains the 2α- 12 C structure as an important component. (author)

Identification of Complete Repertoire of Apis florea Odorant Receptors Reveals Complex Orthologous Relationships with Apis mellifera

Science.gov (United States)

Karpe, Snehal D.; Jain, Rikesh; Brockmann, Axel; Sowdhamini, Ramanathan

2016-01-01

Abstract We developed a computational pipeline for homology based identification of the complete repertoire of olfactory receptor (OR) genes in the Asian honey bee species, Apis florea. Apis florea is phylogenetically the most basal honey bee species and also the most distant sister species to the Western honey bee Apis mellifera, for which all OR genes had been identified before. Using our pipeline, we identified 180 OR genes in A. florea, which is very similar to the number of ORs identified in A. mellifera (177 ORs). Many characteristics of the ORs including gene structure, synteny of tandemly repeated ORs and basic phylogenetic clustering are highly conserved. The composite phylogenetic tree of A. florea and A. mellifera ORs could be divided into 21 clades which are in harmony with the existing Hymenopteran tree. However, we found a few nonorthologous OR relationships between both species as well as independent pseudogenization of ORs suggesting separate evolutionary changes. Particularly, a subgroup of the OR gene clade XI, which had been hypothesized to code cuticular hydrocarbon receptors showed a high number of species-specific ORs. RNAseq analysis detected a total number of 145 OR transcripts in male and 162 in female antennae. Most of the OR genes were highly expressed on the female antennae. However, we detected five distinct male-biased OR genes, out of which three genes (AfOr11, AfOr18, AfOr170P) were shown to be male-biased in A. mellifera, too, thus corroborating a behavioral function in sex-pheromone communication. PMID:27540087

Using DLL as Interface between API an VC#.NET Applications

Directory of Open Access Journals (Sweden)

Marian DARDALA

2006-01-01

Full Text Available This paper presents a solution for using complex Win32API data structures and functions in Visual C# .NET applications. We built DLL (Dynamic Link Library to manage the API functions and data structures and we used DLL modules in a C# application. This is an easier working way compared with the traditional way of importing and managing API’s functions in C# programs.

Programmatic access to logical models in the Cell Collective modeling environment via a REST API.

Science.gov (United States)

Kowal, Bryan M; Schreier, Travis R; Dauer, Joseph T; Helikar, Tomáš

2016-01-01

Cell Collective (www.cellcollective.org) is a web-based interactive environment for constructing, simulating and analyzing logical models of biological systems. Herein, we present a Web service to access models, annotations, and simulation data in the Cell Collective platform through the Representational State Transfer (REST) Application Programming Interface (API). The REST API provides a convenient method for obtaining Cell Collective data through almost any programming language. To ensure easy processing of the retrieved data, the request output from the API is available in a standard JSON format. The Cell Collective REST API is freely available at http://thecellcollective.org/tccapi. All public models in Cell Collective are available through the REST API. For users interested in creating and accessing their own models through the REST API first need to create an account in Cell Collective (http://thecellcollective.org). thelikar2@unl.edu. Technical user documentation: https://goo.gl/U52GWo. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Evidence of Apis cerana Sacbrood virus Infection in Apis mellifera.

Science.gov (United States)

Gong, Hong-Ri; Chen, Xiu-Xian; Chen, Yan Ping; Hu, Fu-Liang; Zhang, Jiang-Lin; Lin, Zhe-Guang; Yu, Ji-Wei; Zheng, Huo-Qing

2016-04-01

Sacbrood virus(SBV) is one of the most destructive viruses in the Asian honeybee Apis cerana but is much less destructive in Apis mellifera In previous studies, SBV isolates infecting A. cerana(AcSBV) and SBV isolates infecting A. mellifera(AmSBV) were identified as different serotypes, suggesting a species barrier in SBV infection. In order to investigate this species isolation, we examined the presence of SBV infection in 318A. mellifera colonies and 64A. cerana colonies, and we identified the genotypes of SBV isolates. We also performed artificial infection experiments under both laboratory and field conditions. The results showed that 38A. mellifera colonies and 37A. cerana colonies were positive for SBV infection. Phylogenetic analysis based on RNA-dependent RNA polymerase (RdRp) gene sequences indicated that A. cerana isolates and most A. mellifera isolates formed two distinct clades but two strains isolated fromA. mellifera were clustered with theA. cerana isolates. In the artificial-infection experiments, AcSBV negative-strand RNA could be detected in both adult bees and larvae ofA. mellifera, although there were no obvious signs of the disease, demonstrating the replication of AcSBV inA. mellifera Our results suggest that AcSBV is able to infectA. melliferacolonies with low prevalence (0.63% in this study) and pathogenicity. This work will help explain the different susceptibilities ofA. cerana and A. melliferato sacbrood disease and is potentially useful for guiding beekeeping practices. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

Identification of Burkholderia spp. in the Clinical Microbiology Laboratory: Comparison of Conventional and Molecular Methods

Science.gov (United States)

van Pelt, Cindy; Verduin, Cees M.; Goessens, Wil H. F.; Vos, Margreet C.; Tümmler, Burkhard; Segonds, Christine; Reubsaet, Frans; Verbrugh, Henri; van Belkum, Alex

1999-01-01

Cystic fibrosis (CF) predisposes patients to bacterial colonization and infection of the lower airways. Several species belonging to the genus Burkholderia are potential CF-related pathogens, but microbiological identification may be complicated. This situation is not in the least due to the poorly defined taxonomic status of these bacteria, and further validation of the available diagnostic assays is required. A total of 114 geographically diverse bacterial isolates, previously identified in reference laboratories as Burkholderia cepacia (n = 51), B. gladioli (n = 14), Ralstonia pickettii (n = 6), B. multivorans (n = 2), Stenotrophomonas maltophilia (n = 3), and Pseudomonas aeruginosa (n = 11), were collected from environmental, clinical, and reference sources. In addition, 27 clinical isolates putatively identified as Burkholderia spp. were recovered from the sputum of Dutch CF patients. All isolates were used to evaluate the accuracy of two selective growth media, four systems for biochemical identification (API 20NE, Vitek GNI, Vitek NFC, and MicroScan), and three different PCR-based assays. The PCR assays amplify different parts of the ribosomal DNA operon, either alone or in combination with cleavage by various restriction enzymes (PCR-restriction fragment length polymorphism [RFLP] analysis). The best system for the biochemical identification of B. cepacia appeared to be the API 20NE test. None of the biochemical assays successfully grouped the B. gladioli strains. The PCR-RFLP method appeared to be the optimal method for accurate nucleic acid-mediated identification of the different Burkholderia spp. With this method, B. gladioli was also reliably classified in a separate group. For the laboratory diagnosis of B. cepacia, we recommend parallel cultures on blood agar medium and selective agar plates. Further identification of colonies with a Burkholderia phenotype should be performed with the API 20NE test. For final confirmation of species identities, PCR

Integration of Environmental Sensors with BIM: case studies using Arduino, Dynamo, and the Revit API

Directory of Open Access Journals (Sweden)

Kensek, K. M.

2014-12-01

Full Text Available This paper investigates the feasibility of connecting environmental sensors such as light, humidity, or CO2 receptors to a building information model (BIM. A base case was created in Rhino; using Grasshopper and Firefly, a simple digital model responded to lighting-levels detected by a photoresistor on an Arduino board. The case study was duplicated using Revit Architecture, a popular BIM software, and Dynamo, a visual programming environment, in an innovative application. Another case study followed a similar procedure by implementing the Revit API directly instead of using Dynamo. Then the process was reversed to demonstrate that not only could data could be sent from sensors to change the 3D model, but changes to parameters of a 3D model could effect a physical model through the use of actuators. It is intended that these virtual/physical prototypes could be used as the basis for testing intelligent façade systems before constructing full size mock-ups.Este estudio investiga la posibilidad de conectar sensores ambientales como de luz, humedad, o dióxido de carbono con un modelo de información de un edificio (siglas BIM en inglés. Un caso base fue creado en Rhino; usando Grasshopper and Firefly, donde un simple modelo digital respondió a niveles de luz detectados por un foto resistor en una tarjeta Arduino. El caso de estudio fue duplicado usando Revit Architecture, una herramienta popular en BIM, y Dynamo, un ambiente de programación gráfica, en una creativa aplicación. Un segundo caso de estudio siguió un procedimiento similar implementando Revit API directamente en vez de usar Dynamo. Entonces el proceso fue revertido para demostrar que no solamente la información podría ser enviada desde sensores para cambiar el modelo tridimensional, pero cambios en los parámetros de un modelo tridimensional podrían afectar un modelo físico mediante el uso de actuadores. Se espera que esos modelos virtuales puedan ser usados como base para

Collision-induced intramultiplet mixing for the Ne**[(2p)5(3p)] + He or Ne system

International Nuclear Information System (INIS)

Manders, M.P.I.

1988-01-01

For the Ne**-He case, experimental data are confronted with quantum mechanical calculations. Quantum mechanical coupled-channel calculations using model potentials as input are presented, followed by a semiclassical approach which provides more physical insight. Experimental results are presented for the Ne**-Ne system with a discussion of the general principles involved in symmetrization. 184 refs.; 93 figs.; 19 tabs

Estudios organolépticos, fisicoquímicos, microbiológicos e interacción con excipientes farmacéuticos de un extracto purificado de cera de Apis mellifera Organoleptic, physicochemical and microbiological studies and its interaction with pharmaceutical excipients of a purified extract from Apis mellifera wax

Directory of Open Access Journals (Sweden)

Víctor Luis González Canavaciolo

2010-09-01

Full Text Available El D-002, ingrediente activo antioxidante extraído de la cera de abejas Apis mellifera, fue caracterizado desde el punto de vista físicoquímico, de igual forma se analizó su interacción con excipientes de interés farmacéutico. El D-002 es un polvo fluido inodoro de color blanco a crema, con pérdidas por secado £ 1 %; es insoluble en agua y etanol, y muy ligeramente soluble en otros disolventes orgánicos. Su composición, determinada por cromatografía de gases, fue: 1-tetracosanol (6-15 %, 1-hexacosanol (7-20 %, 1-octacosanol (12-20 %, 1-triacontanol (25-35 % 1-dotriacontanol (18-25 % y 1-tetratriacontanol (£ 7,5 %, para una pureza ³ 85 %. Fue estable durante 5 años en la zona climática IV y su análisis por calorimetría diferencial de barrido mostró 2 transiciones de fusión a 59,0 y 81,1 °C sin descomposición, una alta estabilidad térmica hasta 200 °C, así como la ausencia de interacciones con lactosa, almidón, croscarmelosa sódica, polivinil pirrolidona, celulosa microcristalina y estearato de magnesio, lo que posibilita el empleo de estos excipientes en la formulación de las tabletas.The D002, an antioxidant active ingredient extracted from the Apis mellifera bees wax was characterized from the physicochemical point of view analyzing its interaction with excipients of pharmaceutical interest. The D-002 is a creamy white odourless fluid powder with losses by £ 1 % dry; it is water and ethanol insoluble and very slightly soluble in other organic solvents. Its composition, determined by gas chromatography was: 1-tetracosanol (6-15 %, 1-hexacosanol (7-20 %, 1-octacosanol (12-20 %, 1-triacontanol (25-35 %, 1-dotriacontanol (18-25 % and 1-tetratriacontaol (£ 7,5 % for ³ 85 % of purity. It remained stable during 5 years in the IV climatic zone and its analysis by differential scanning calorimetry showed 2 fusion transitions at 59.0 and 81.1 °C. without decomposition, a high thermal stability up to 200 °C, as well as a

Online maps with APIs and webservices

CERN Document Server

Peterson, Michael P

2014-01-01

With the Internet now the primary method of accessing maps, this volume examines developments in the world of online map delivery, focusing in particular on application programmer interfaces such as the Google Maps API, and their utility in thematic mapping.

A new detrended semipartial cross-correlation analysis: Assessing the important meteorological factors affecting API

International Nuclear Information System (INIS)

Shen, Chen-Hua

2015-01-01

To analyze the unique contribution of meteorological factors to the air pollution index (API), a new method, the detrended semipartial cross-correlation analysis (DSPCCA), is proposed. Based on both a detrended cross-correlation analysis and a DFA-based multivariate-linear-regression (DMLR), this method is improved by including a semipartial correlation technique, which is used to indicate the unique contribution of an explanatory variable to multiple correlation coefficients. The advantages of this method in handling nonstationary time series are illustrated by numerical tests. To further demonstrate the utility of this method in environmental systems, new evidence of the primary contribution of meteorological factors to API is provided through DMLR. Results show that the most important meteorological factors affecting API are wind speed and diurnal temperature range, and the explanatory ability of meteorological factors to API gradually strengthens with increasing time scales. The results suggest that DSPCCA is a useful method for addressing environmental systems. - Highlights: • A detrended multiple linear regression is shown. • A detrended semipartial cross correlation analysis is proposed. • The important meteorological factors affecting API are assessed. • The explanatory ability of meteorological factors to API gradually strengthens with increasing time scales.

A new detrended semipartial cross-correlation analysis: Assessing the important meteorological factors affecting API

Energy Technology Data Exchange (ETDEWEB)

Shen, Chen-Hua, E-mail: shenandchen01@163.com [College of Geographical Science, Nanjing Normal University, Nanjing 210046 (China); Jiangsu Center for Collaborative Innovation in Geographical Information Resource, Nanjing 210046 (China); Key Laboratory of Virtual Geographic Environment of Ministry of Education, Nanjing 210046 (China)

2015-12-04

To analyze the unique contribution of meteorological factors to the air pollution index (API), a new method, the detrended semipartial cross-correlation analysis (DSPCCA), is proposed. Based on both a detrended cross-correlation analysis and a DFA-based multivariate-linear-regression (DMLR), this method is improved by including a semipartial correlation technique, which is used to indicate the unique contribution of an explanatory variable to multiple correlation coefficients. The advantages of this method in handling nonstationary time series are illustrated by numerical tests. To further demonstrate the utility of this method in environmental systems, new evidence of the primary contribution of meteorological factors to API is provided through DMLR. Results show that the most important meteorological factors affecting API are wind speed and diurnal temperature range, and the explanatory ability of meteorological factors to API gradually strengthens with increasing time scales. The results suggest that DSPCCA is a useful method for addressing environmental systems. - Highlights: • A detrended multiple linear regression is shown. • A detrended semipartial cross correlation analysis is proposed. • The important meteorological factors affecting API are assessed. • The explanatory ability of meteorological factors to API gradually strengthens with increasing time scales.

The MiniBooNE Detector

OpenAIRE

MiniBooNE Collaboration

2008-01-01

The MiniBooNE neutrino detector was designed and built to look for muon-neutrino to electron-neutrino oscillations in the mixing parameter space region where the LSND experiment reported a signal. The MiniBooNE experiment used a beam energy and baseline that were an order of magnitude larger than those of LSND so that the backgrounds and systematic errors would be completely different. This paper provides a detailed description of the design, function, and performance of the MiniBooNE detector.

Eksplorasi Potensi Ekowisata di Kawasan Api Tak Kunjung Pada Kabupaten Pamekasan

Directory of Open Access Journals (Sweden)

Dewi Kartika Sari Susena

2015-04-01

Full Text Available Penelitian ini bertujuan untuk mengetahui aspek potensi ekowisata di kawasan Api Tak Kunjung Padam kabupaten Pamekasan dan persepsi masyarakat sekitar tentang potensi ekowisata yang ada. Metode pengambilan data meliputi mendapatkan informasi umum dari Key person dengan menggunakan teknik purposive sampling, penelusuran pustaka, observasi lapang, pengumpulan data lokasi berdasarkan persepsi masyarakat dengan pemilihan responden dengan menggunakan teknik purposive sampling dan wawancara semi terstruktur. Sumber daya alam yang ada di sekitar kawasan objek wisata yang berpotensi untuk mendukung ekowisata yaitu, objek wisata Api Tak Kunjung Padam, umbi bentul (Colocasia esculenta L., lahan pertanian Singkong (Manihot esculenta Crantz, Kacang hijau (Phaseolus radiatus L., Pisang (Musa paradisiaca L. dan Jagung (Zea mays L., rengginang lorjuk, jubada, kaldu kokot, rujak dan campur madura. Berdasarkan hasil wawancara diketahui bahwa hasil panen dari lahan pertanian dimanfaatkan masyarakat setempat untuk menambah perekonomian dengan cara dijual di kawasan Api Tak Kunjung Padam maupun di pasar. Masyarakat setempat juga belum banyak mengetahui potensi sumber daya tersebut untuk dimanfaatkan sebagai pendukung konservasi lingkungan secara umum di wilayah tersebut. Kata Kunci : Api Tak Kunjung Padam, ekowisata, Persepsi.

DIGITAL TRANSFORMATION : HOW APIS DRIVE BUSINESS MODEL CHANGE AND INNOVATION

OpenAIRE

Hellbe, Simon; Leung, Peter

2015-01-01

Over the years, information technology has created opportunities to improve and extend businesses and to start conducting business in new ways. With the evolution of IT, all businesses and industries are becoming increasingly digitized. This process, or coevolution, of IT and business coming together is called digital transformation. One of the recent trends in this digital transformation is the use of application programmable interfaces (APIs). APIs are standardized digital communication int...

The NeXus data format.

Science.gov (United States)

Könnecke, Mark; Akeroyd, Frederick A; Bernstein, Herbert J; Brewster, Aaron S; Campbell, Stuart I; Clausen, Björn; Cottrell, Stephen; Hoffmann, Jens Uwe; Jemian, Pete R; Männicke, David; Osborn, Raymond; Peterson, Peter F; Richter, Tobias; Suzuki, Jiro; Watts, Benjamin; Wintersberger, Eugen; Wuttke, Joachim

2015-02-01

NeXus is an effort by an international group of scientists to define a common data exchange and archival format for neutron, X-ray and muon experiments. NeXus is built on top of the scientific data format HDF5 and adds domain-specific rules for organizing data within HDF5 files, in addition to a dictionary of well defined domain-specific field names. The NeXus data format has two purposes. First, it defines a format that can serve as a container for all relevant data associated with a beamline. This is a very important use case. Second, it defines standards in the form of application definitions for the exchange of data between applications. NeXus provides structures for raw experimental data as well as for processed data.

Using the RxNorm web services API for quality assurance purposes.

Science.gov (United States)

Peters, Lee; Bodenreider, Olivier

2008-11-06

Auditing large, rapidly evolving terminological systems is still a challenge. In the case of RxNorm, a standardized nomenclature for clinical drugs, we argue that quality assurance processes can benefit from the recently released application programming interface (API) provided by RxNav. We demonstrate the usefulness of the API by performing a systematic comparison of alternative paths in the RxNorm graph, over several thousands of drug entities. This study revealed potential errors in RxNorm, currently under review. The results also prompted us to modify the implementation of RxNav to navigate the RxNorm graph more accurately. The RxNav web services API used in this experiment is robust and fast.

An API for Integrating Spatial Context Models with Spatial Reasoning Algorithms

DEFF Research Database (Denmark)

Kjærgaard, Mikkel Baun

2006-01-01

The integration of context-aware applications with spatial context models is often done using a common query language. However, algorithms that estimate and reason about spatial context information can benefit from a tighter integration. An object-oriented API makes such integration possible...... and can help reduce the complexity of algorithms making them easier to maintain and develop. This paper propose an object-oriented API for context models of the physical environment and extensions to a location modeling approach called geometric space trees for it to provide adequate support for location...... modeling. The utility of the API is evaluated in several real-world cases from an indoor location system, and spans several types of spatial reasoning algorithms....

Apoptosis inhibitor 5 (API-5; AAC-11; FIF) is upregulated in human carcinomas in vivo.

Science.gov (United States)

Koci, Lenka; Chlebova, Katarina; Hyzdalova, Martina; Hofmanova, Jirina; Jira, Miroslav; Kysela, Petr; Kozubik, Alois; Kala, Zdenek; Krejci, Pavel

2012-04-01

Apoptosis inhibitor 5 (API-5) is a 55 kDa nuclear protein with potent anti-apoptotic signaling in tumor cells in vitro. In this study, we analyzed the expression of the API-5 protein in vivo in a broad spectrum of human carcinomas, including those of the colon, lung, liver, kidney, pancreas, stomach and esophagus using tumor tissues obtained during tumor resection. The results showed significant upregulation of API-5 expression in biopsies of lung (23%, n=13) and colorectal tumors (33%, n=27) in comparison with biopsies from the adjacent normal tissue. Colon cancer biopsies were used to study the cell populations with an upregulated level of expression of API-5 more closely. Using a magnetic bead-based selection for the epithelial cell marker EpCAM, we purified epithelial cells from the tumor and control tissues and analyzed these cells for API-5 expression by western immunoblotting. We observed that EpCAM-positive tumor cells expressed API-5 in all three colorectal cancer cases tested, in contrast to the control EpCAM-positive and EpCAM-negative cells isolated from the control or tumor tissues. These data suggest that the expression of the API-5 protein is upregulated in tumor epithelial cells and may serve as a prognostic marker in colorectal cancer.

Enersave API: Android-based power-saving framework for mobile devices

Directory of Open Access Journals (Sweden)

A.M. Muharum

2017-06-01

Full Text Available Power consumption is a major factor to be taken into consideration when using mobile devices in the IoT field. Good Power management requires proper understanding of the way in which it is being consumed by the end-devices. This paper is a continuation of the work in Ref. [1] and proposes an energy saving API for the Android Operating System in order to help developers turn their applications into energy-aware ones. The main features heavily used for building smart applications, greatly impact battery life of Android devices and which have been taken into consideration are: Screen brightness, Colour scheme, CPU frequency, 2G/3G network, Maps, Low power localisation, Bluetooth and Wi-Fi. The assessment of the power-saving API has been performed on real Android devices and also compared to the most powerful power-saving applications – DU Battery Saver and Battery Saver 2016 – currently available on the Android market. Comparisons demonstrate that the Enersave API has a significant impact on power saving when incorporated in android applications. While DU Battery Saver and Battery Saver 2016 help saving 22.2% and 40.5% of the battery power respectively, the incorporation of the Enersave API in android applications can help save 84.6% of battery power.

Physical stability of API/polymer-blend amorphous solid dispersions.

Science.gov (United States)

Lehmkemper, Kristin; Kyeremateng, Samuel O; Bartels, Mareike; Degenhardt, Matthias; Sadowski, Gabriele

2018-03-01

The preparation of amorphous solid dispersions (ASDs) is a well-established strategy for formulating active pharmaceutical ingredients by embedding them in excipients, usually amorphous polymers. Different polymers can be combined for designing ASDs with desired properties like an optimized dissolution behavior. One important criterion for the development of ASD compositions is the physical stability. In this work, the physical stability of API/polymer-blend ASDs was investigated by thermodynamic modeling and stability studies. Amorphous naproxen (NAP) and acetaminophen (APAP) were embedded in blends of hydroxypropyl methylcellulose acetate succinate (HPMCAS) and either poly(vinylpyrrolidone) (PVP) or poly(vinylpyrrolidone-co-vinyl acetate) (PVPVA64). Parameters for modeling the API solubility in the blends and the glass-transition temperature curves of the water-free systems with Perturbed-Chain Statistical Associating Fluid Theory and Kwei equation, respectively, were correlated to experimental data. The phase behavior for standardized storage conditions (0%, 60% and 75% relative humidity (RH)) was predicted and compared to six months-long stability studies. According to modeling and experimental results, the physical stability was reduced with increasing HPMCAS content and increasing RH. This trend was observed for all investigated systems, with both APIs (NAP and APAP) and both polymer blends (PVP/HPMCAS and PVPVA64/HPMCAS). PC-SAFT and the Kwei equation turned out to be suitable tools for modeling and predicting the physical stability of the investigated API/polymer-blends ASDs. Copyright © 2017 Elsevier B.V. All rights reserved.

Progress On Neutrino-Proton Neutral-Current Scattering In MicroBooNE

Energy Technology Data Exchange (ETDEWEB)

Pate, Stephen [New Mexico State U.

2017-01-16

The MicroBooNE Experiment at the Fermi National Accelerator Laboratory, an 89-ton active mass liquid argon time projection chamber, affords a unique opportunity to observe low-$Q^2$ neutral-current neutrino-proton scattering events. Neutral-current neutrino-proton scattering at $Q^2 < 1$ GeV$^2$ is dominated by the proton's axial form factor, which can be written as a combination of contributions from the up, down, and strange quarks: $G_A(Q^2) = \\frac{1}{2}[-G_A^u(Q^2)+G_A^d(Q^2)+G_A^s(Q^2)]$. The contribution from up and down quarks has been established in past charged-current measurements. The contribution from strange quarks at low $Q^2$ remains unmeasured; this is of great interest since the strange quark contribution to the proton spin can be determined from the low-$Q^2$ behavior: $\\Delta S = G_A^s(Q^2=0)$. MicroBooNE began operating in the Booster Neutrino Beam in October 2015. I will present the status in observing isolated proton tracks in the MicroBooNE detector as a signature for neutral-current neutrino-proton events. The sensitivity of the MicroBooNE experiment for measuring the strange quark contribution to the proton spin will be discussed.

The end of polling: why and how to transform a REST API into a Data Streaming API?

CERN Multimedia

CERN. Geneva

2017-01-01

We know interactivity is the key to keep our user’s interest alive but we can’t reduce animation to UI anymore. Twitter, Waze, Slack… users are used to have real-time data in applications they love. But how can you turn your static API into a stream of data? By pulling? Pushing? Webhook-ing? When talking about data streaming, we often think about WebSockets. But have you ever heard of Server-Sent Events? In this tools-in-action we will compare those technologies to understand which one you should opt for depending on your usecase, and I’ll show you how we have been reducing the amount of data to transfer even further with JSON-Patch. And because real-time data is not only needed by web (and because it’s much more fun), I’ll show you how we can make a drone dance on streamed APIs.

Pemanfaatan Google Maps Api Untuk Visualisasi Data Base Transceiver Station

OpenAIRE

Rani, Septia

2016-01-01

This paper discusses the use of the Google Maps API to perform data visualization for Base Transceiver Station (BTS) data. BTS are typically used by telecommunications companies to facilitate wireless communication between communication devices with the network operator. Each BTS has important information such as it's location, it's transaction traffic, as well as information about revenue. With the implementation of BTS data visualization using the Google Maps API, key information owned by e...

PEMANFAATAN GOOGLE MAPS API UNTUK VISUALISASI DATA BASE TRANSCEIVER STATION

OpenAIRE

Rani, Septia

2016-01-01

This paper discusses the use of the Google Maps API to perform data visualization for Base Transceiver Station (BTS) data. BTS are typically used by telecommunications companies to facilitate wireless communication between communication devices with the network operator. Each BTS has important information such as it’s location, it’s transaction traffic, as well as information about revenue. With the implementation of BTS data visualization using the Google Maps API, key information owned by e...

Pemanfaatan Google Maps Api Untuk Visualisasi Data Base Transceiver Station

OpenAIRE

Rani, Septia

2016-01-01

This paper discusses the use of the Google Maps API to perform data visualization for Base Transceiver Station (BTS) data. BTS are typically used by telecommunications companies to facilitate wireless communication between communication devices with the network operator. Each BTS has important information such as it’s location, it’s transaction traffic, as well as information about revenue. With the implementation of BTS data visualization using the Google Maps API, key information owned by e...

CALIMACO: desarrollo de un servicio de bibliotecario virtual para la interacción multimodal con dispositivos móviles

Directory of Open Access Journals (Sweden)

Griol, David

2016-06-01

Full Text Available In recent years smart mobile devices have bolstered new interaction scenarios that require more sophisticated human-machine interfaces. The leading developers of operating systems for these devices now provide APIs (Application Programming Interface for developers to implement their own applications, including different solutions for developing graphical interfaces, control sensors and providing oral interaction. Despite the usefulness of these resources, defined strategies are still needed for developing multimodal interfaces to take greater advantage of these devices for identifying and meeting the needs of users. Currently, these applications are typically ad-hoc and facilitate oral communication only through simple commands. In this paper we propose the practical application of context-sensitive multimodal conversational agents to provide advanced library services that dynamically consider specific user needs and preferences, as well as the specific characteristics of the environment in which the interaction occurs. Such agents would improve and customize the service provided by a mobile device with Internet access. Our proposal integrates features of Android APIs on a modular architecture emphasizing the management of interactions and context awareness in order to create robust applications that can be easily updated and adapted to the user.Los dispositivos móviles inteligentes han fomentado en los últimos años nuevos escenarios de interacción que requieren interfaces persona-máquina más sofisticados. Los principales desarrolladores de sistemas operativos para estos dispositivos proporcionan actualmente APIs (Application Programming Interfaces para que los desarrolladores puedan implementar sus propias aplicaciones, incluyendo diferentes soluciones para el desarrollo de interfaces gráficas, el control de sensores y proveer interacción oral. A pesar de la utilidad de este tipo de recursos, no se han definido aún estrategias para

The NeXus data format

OpenAIRE

Könnecke, Mark; Akeroyd, Frederick A.; Osborn, Raymond; Peterson, Peter F.; Richter, Tobias; Suzuki, Jiro; Watts, Benjamin; Wintersberger, Eugen; Wuttke, Joachim; Bernstein, Herbert J.; Brewster, Aaron S.; Campbell, Stuart I.; Clausen, Björn; Cottrell, Stephen; Hoffmann, Jens Uwe

2015-01-01

NeXus is an effort by an international group of scientists to define a common data exchange and archival format for neutron, X-ray and muon experiments. NeXus is built on top of the scientific data format HDF5 and adds domain-specific rules for organizing data within HDF5 files, in addition to a dictionary of well defined domain-specific field names. The NeXus data format has two purposes. First, it defines a format that can serve as a container for all relevant data associated with a beamlin...

The MiniBooNE detector

International Nuclear Information System (INIS)

Aguilar-Arevalo, A.A.; Anderson, C.E.; Bartoszek, L.M.; Bazarko, A.O.; Brice, S.J.; Brown, B.C.; Bugel, L.; Cao, J.; Coney, L.; Conrad, J.M.; Cox, D.C.; Curioni, A.; Djurcic, Z.; Finley, D.A.; Fleming, B.T.; Ford, R.; Garcia, F.G.; Garvey, G.T.; Green, C.; Green, J.A.

2009-01-01

The MiniBooNE neutrino detector was designed and built to look for ν μ →ν e oscillations in the (sin 2 2θ,Δm 2 ) parameter space region where the LSND experiment reported a signal. The MiniBooNE experiment used a beam energy and baseline that were an order of magnitude larger than those of LSND so that the backgrounds and systematic errors would be completely different. This paper provides a detailed description of the design, function, and performance of the MiniBooNE detector.

Strangeness production in antiproton annihilation at rest on sup 3 He, sup 4 He and sup 20 Ne

Energy Technology Data Exchange (ETDEWEB)

Balestra, F. (Cagliari Univ. (Italy). Dipt. di Scienze Fisiche Istituto Nazionale di Fisica Nucleare, Cagliari (Italy)); Batusov, Yu.A.; Falomkin, I.V.; Pontecorvo, G.B.; Rozhdestvensky, A.M.; Sapozhnikov, M.G.; Tretyak, V.I. (Joint Inst. for Nuclear Research, Dubna (USSR)); Bendiscioli, G.; Filippini, V.; Rotondi, A.; Salvini, P.; Venaglioni, A. (Pavia Univ. (Italy). Dipt. di Fisica Nucleare e Teorica Istituto Nazionale di Fisica Nucleare, Pavia (Italy)); Bossolasco, S.; Bussa, M.P.; Busso, L.; Fava, L.; Ferrero, L.; Panzieri, D.; Piragino, G.; Tosello, F. (Turin Univ. (Italy). Ist. di Fisica Generale Istituto Nazionale di Fisica Nucleare, Turin (Italy)); Breivik, F.O.; Danielsen, K.M.; Jacobsen, T.; Soerensen, S.O. (Oslo Univ. (Norway). Physics Dept.); Guaraldo, C.; Maggiora, A. (Istituto Nazionale di Fisica Nucleare, Frascati (Italy). Lab. Nazionale di Frascati); Haatuft, A.; Halsteinslid, A.; Myklebost, K.; Olsen, J.M. (Bergen Univ. (Norway). Dept. of Physics); Lodi Rizzini,

1991-05-13

New data are reported on antiproton annihilations at rest with production of {Lambda} and K{sub S}{sup 0}, using a streamer chamber with {sup 3}He, {sup 4}He and {sup 20}Ne as gas targets. The data include {Lambda}, K{sub S}{sup 0}, {Lambda}K{sub S}{sup 0} and K{sub S}{sup 0}K{sub S}{sup 0} production rates and momentum distributions, {pi}{sup -} momentum spectra, mean numbers of charged particles generally and of negatively charged particles separately for different reaction channels. The yields are compared to simple combinatorial calculations based on the extreme assumptions of {Lambda} production via B=1 or via B=0 (anti K rescattering) annihilations. {Lambda} and K{sub S}{sup 0} momentum spectra are compared to simple model calculations where B=0 and B=1 annihilations with and without final-state interactions are considered. A review of existing data on {Lambda} and K{sub S}{sup 0} production is presented, showing the dependence on the anti p momentum and on the mass number of the target. (orig.).

MiniBooNE Oscillation Results

International Nuclear Information System (INIS)

Djurcic, Zelimir

2009-01-01

These proceedings summarize the MiniBooNE ν μ → ν e results, describe the first (bar ν) μ → (bar ν) e result, and current analysis effort with the NuMI neutrinos detected in the miniBooNE detector

WEB 2.0: DESAFIO INSUPERÁVEL OU OPORTUNIDADE PARA A INCLUSÃO DIGITAL?

Directory of Open Access Journals (Sweden)

Mauro Marafiga Camozzato

2013-03-01

Full Text Available Este artigo tem como objetivo abordar a problemática da exclusão digital sob o enfoque do analfabetismo funcional, salientando a importância da inclusão social efetiva como elemento importante na definição dessas terminologias. Também é objetivo do artigo observar esses conceitos quando relacionados com a aceleração das necessidades sociais e econômicas trazidas pela sociedade conectada em rede, notadamente após o advento da Web 2.0. Busca-se questionar – sem responder - se o cenário atual é de desafio desanimador ou de oportunidade para a inclusão digital. Para isso, são analisadas as conceituações trabalhadas antecipadamente, de “analfabetismo funcional” e de “exclusão digital”, em comparação com as novas necessidades e oportunidades sociais surgidas a partir da conexão instantânea oferecida pelas redes sociais e plataformas de colaboração. Para fins de ilustração otimista, são apresentados alguns exemplos de iniciativas de inclusão digital em redes sociais inclusivas, as quais obtiveram resultados satisfatórios. Ao fim, tece-se alguns comentários sobre políticas governamentais aplicadas atualmente, apenas para reflexão quanto a sua utilidade no atual cenário tecnológico.

Análisis del proceso de corrosión producida en la junta de soldadura de tubería API 5L X70, por el transporte de crudo.

OpenAIRE

Cahueñas Cotacachi, Luis Guillermo; Ballesteros Medina, Adolfo Luis

2012-01-01

177 hojas : ilustraciones, 29 x 21 cm + CD-ROM 4132 En el presente tema de tesis se analiza la velocidad de corrosión producida por el agua sedimentada de crudo en la zona interna del cordón de soldadura de una tubería API 5L X70 con electrodos E6010 y E7018. Se utiliza el método experimental mediante una cámara de niebla salina desarrollada para simular el medio corrosivo sobre los que se encuentra trabajando la tubería de oleoducto y soldadura, según los estándares internacionales para l...

Estudo do comportamento nutricional dos zangões(Apis mellifera L. após diferentes tempos de jejum

Directory of Open Access Journals (Sweden)

Italo Souza Aquino

2013-05-01

Full Text Available A aprendizagem olfativa de zangões de abelhas africanizadas (Apis mellifera L. tem sido investigada em condicionamento clássico (CC através do reflexo da extensão da probóscide (PER. O CC entre membros da casta das abelhas merece estudos que possam mostrar diferenças e semelhanças no aprendizado associativo entre esses indivíduos. Zangões e operárias de A. mellifera L. foram igualmente confinados em pequenos tubos de metal e submetidos a diferentes períodos de privação 12, 16, 20 e 24 horas. Os indivíduos sobreviventes a esses períodos foram submetidos a 24 provas em que receberam 12 apresentações de estímulos condicional (EC e incondicional (EI pareados durante aquisição e 12 apresentações de EC na extinção. Observou-se que os longos períodos de jejum não causam grandes retardos da aprendizagem nos zangões. Porém, para que se obtenha um melhor desempenho destes no procedimento de condicionamento recomenda-se períodos de jejum iguais ou inferiores a 12h.

On the reaction to deprecation of clients of 4 + 1 popular Java APIs and the JDK

NARCIS (Netherlands)

Sawant, A.A.; Robbes, Romain; Bacchelli, A.

2017-01-01

Application Programming Interfaces (APIs) are a tremendous resource—that is, when they are stable. Several studies have shown that this is unfortunately not the case. Of those, a large-scale study of API changes in the Pharo Smalltalk ecosystem documented several findings about API deprecations

Isotopic effect of the mean lifetimes of the NeAr2+ doubly charged rare-gas dimer

International Nuclear Information System (INIS)

Ben-Itzhak, I.; Bouhnik, J.P.; Chen, Z.; Gertner, I.; Heinemann, C.; Koch, W.; Lin, C.D.; Rosner, B.

1995-01-01

It has been suggested recently by Chen et al. [Phys. Rev. A 49, 3472 (1994)] that the measured long-lived NeAr 2+ formed in fast NeAr + + Ar charge-stripping collisions is mostly in its v=12 vibrational state bound to the electronic ground state, and that this molecular ion decays by tunneling through the potential barrier. Such a decay rate is expected to depend strongly on the reduced mass of the molecular ion leading to large isotopic effects. We have measured the mean lifetimes of the 20 Ne 40 Ar 2+ and 22 Ne 40 Ar 2+ isotopes in order to see this isotopic effect. Surprisingly, the mean lifetimes of both isotopes are similar to each other. Thus, it is suggested that the observed NeAr 2+ molecular ions do not decay via a tunneling mechanism, which would indicate that they reside in the metastable electronic ground state. Rather, electronic transitions from bound or metastable excited states into other repulsive states are the origin for the experimentally observed decay. Qualitative estimates for the shapes and ordering of these states in the electronic spectrum of NeAr 2+ are given

Web 2.0 para la Biblioteca Digital de Nueva Generación (BDNG)

OpenAIRE

Barraza Difilippo, José Rafael

2010-01-01

El desarrollo del presente trabajo tiene como objetivo principal diseñar e implementar herramientas de la WEB 2.0 en el sistema BDNG (Biblioteca Digital de Nueva Generación) para mejorar la interacción del usuario con dicha plataforma, y así creando comunidades virtuales científicas interuniversitarias y redes de conocimiento que beneficiarán la producción científica del país.

Study of some excited states in 21Ne-21Na, 18O-18F and 15N-15O nuclei

International Nuclear Information System (INIS)

Drain, D.

1977-01-01

The study of 21 Ne- 21 Na, 18 O- 18 F and 15 N- 15 O nuclei was performed through proton capture and transfer reactions and allows to determine the spins and parities of some excited states, give the gamma deexcitation schemes of these levels, compute the neutron and proton reduced width γ 2 sub(n) and γ 2 sub(p). The levels studied are: in 21 Na 4.15 20 Ne(p,p), (p,p'), (p,p'γ) and (pγ) reactions) and in 21 Ne: E(exc)=4.73, 5.69 and 5.78 MeV ( 20 Ne (p,p) reaction); in 18 O: E(exc) 17 O(d,p) reaction); in 15 O: 8.92 MeV doublet and 8.98 MeV level (angular correlation 14 N(p,γγ) and in 15 N: 9.05 14 N(d,p) reaction). A comparison with theoretical results is discussed and analog states are pointed out [fr

Search without Boundaries Using Simple APIs

Science.gov (United States)

Tong, Qi

2009-01-01

The U.S. Geological Survey (USGS) Library, where the author serves as the digital services librarian, is increasingly challenged to make it easier for users to find information from many heterogeneous information sources. Information is scattered throughout different software applications (i.e., library catalog, federated search engine, link resolver, and vendor websites), and each specializes in one thing. How could the library integrate the functionalities of one application with another and provide a single point of entry for users to search across? To improve the user experience, the library launched an effort to integrate the federated search engine into the library's intranet website. The result is a simple search box that leverages the federated search engine's built-in application programming interfaces (APIs). In this article, the author describes how this project demonstrated the power of APIs and their potential to be used by other enterprise search portals inside or outside of the library.

Electronic Spectroscopy of B Atoms and B2 Molecules Isolated in Para-H2, Normal-D2, Ne, Ar, Kr, and Xe Matrices

National Research Council Canada - National Science Library

Tam, Simon

2000-01-01

...), Ne, Ar, Kr, and Xe matrices, and of B2 molecules in Ne, Ar, Kr, and Xe matrices. The 2s(sup 2)3s((sup 2)S) left arrow 2s(sup 2)2p((sup 2)P) B atom Rydberg absorption suffers large gas-to-matrix blue shifts, increasing...

Development of an in-line Raman spectroscopic method for continuous API quantification during twin-screw wet granulation.

Science.gov (United States)

Harting, Julia; Kleinebudde, Peter

2018-04-01

Raman spectroscopy was evaluated as a process analytical technology (PAT) tool for continuous API quantification during twin-screw wet granulation. Therefore, a Raman probe was implemented in front of the granulator barrel. This setup enabled the collection of Raman spectra upon a constant granule flow. To develop an in-line PLS calibration model, eight binary mixtures of the API and lactose monohydrate with API contents between 5 and 50% were pre-blended and granulated in a twin-screw granulator with a screw speed of 150 rpm and a powder feed rate of 40 g/min. Water was used as a granulation liquid with different liquid to solid ratios depending on the API content. Ibuprofen and diclofenac sodium were chosen as model drugs and separated PLS models were built for each API. The predictive performance of the developed PLS models was determined by granulating and monitoring new test samples containing different API concentrations. This evaluation showed that the models were able to predict the API concentration with an RMSEP of 0.59% for ibuprofen and 1.5% for diclofenac sodium. In a second part, the developed in-line Raman spectroscopic method was used to determine the API concentration during a split feeding process. Therefore, the API and lactose monohydrate were added by two independently adjustable feeders into the twin-screw granulator barrel. The in-line spectroscopy analysis which was verified by UV-analysis indicated that the mixing ability of the twin-screw granulator was good for the used settings and all adjusted API concentrations. Copyright © 2018 Elsevier B.V. All rights reserved.

Flood warning level forecasting for ungauged catchments by means of a combined API storage concept

International Nuclear Information System (INIS)

Lehmann, T; Holzmann, H

2008-01-01

The knowledge of the expected dimension of the flood peak is of major importance for security and warning services to take preventive measures. In this paper the authors want to introduce the concept of the Antecedent Precipitation Index (API) as a possible variable to estimate runoff warning classes. The aim was (a) to define API warning classes which correspond to runoff warning classes at a certain runoff gauge and (b) apply the method to ungauged basins. To consider time and state dependant rainfall losses a spatially distributed linear storage concept was applied to intercept the actual rainfall. The 3-parameter API function was fitted to several flood events at observed gauges within the district of lower Austria and lead to a set of optimized parameters. Through extreme value statistics the 1, 5 and 30 years API extremes were derived and set into correlation to the corresponding flood events. These API extremes together with the optimized API parameters were spatially interpolated and thus transferred to ungauged basins. The calculated flood events had the tendency to underestimate the smaller flood frequencies whereas the extreme flood classes could be reliably performed.

A Fine-Grained API Link Prediction Approach Supporting CMDA Mashup Recommendation

Science.gov (United States)

Zhang, J.; Bao, Q.; Lee, T. J.; Ramachandran, R.; Lee, S.; Pan, L.; Gatlin, P. N.; Maskey, M.

2017-12-01

Service (API) discovery and recommendation is key to the wide spread of service oriented architecture and service oriented software engineering. Service recommendation typically relies on service linkage prediction calculated by the semantic distances (or similarities) among services based on their collection of inherent attributes. Given a specific context (mashup goal), however, different attributes may contribute differently to a service linkage. In this work, instead of training a model for all attributes as a whole, a novel approach is presented to simultaneously train separate models for individual attributes. Our contributions are summarized in three-fold. First is that we have developed a scalable attribute-level data model, featuring scalability and extensibility. We have extended Multiplicative Attribute Graph (MAG) model to represent node profiles featuring rich categorical attributes, while relaxing its constraint of requiring a priori knowledge of predefined attributes. LDA is leveraged to dynamically identify attributes based on attribute modeling, and multiple Gaussian fit is applied to find global optimal values. The second contribution is that we have seamlessly integrated the latent relationships between API attributes as well as observed network structure based on historical API usage data. Such a layered information model enables us to predict the probability of a link between two APIs based on their attribute link affinities carrying a variety of information including meta data, semantic data, historical usage data, as well as crowdsourcing user comments and annotations. The third contribution is that we have developed a finegrained context-aware mashup-API recommendation technique. On top of individual models trained for separate attributes, a dedicated layer is trained to represent the latent attribute distribution regarding mashup purpose, i.e., sensitivity of attributes to context. Thus, given the description of an intended mashup, the

ANALISA PEREKAMAN DATA SUARA DARI SISTEM BLACKBOX PADA KERETA API

Directory of Open Access Journals (Sweden)

Emy Setyaningsih

2016-01-01

Full Text Available             Makalah ini akan membahas tentang penerapan black box pada kereta api yang diadopsi pertama kali pada pesawat, dengan parameter perekam suara hingga waktu simpan kurang dari 1 hari 8 jam pada media penyimpanan SD Card. Tujuan dari pengujian pada makalah ini adalah membandingkan sumber suara terhadap jarak penerima, sebagai parameter perubahan tingkat suara “dB”. Sistem perekaman suara yang akan ditempatkan pada kereta api ini menggunakan modul rangkaian terintregasi WTR010. Voice record WTR010 merupakan modul rangkaian terintegrasi untuk merekam suara sendiri atau pun suara dari file music / video pada komputer dengan sangat mudah. Modul ini bisa merekam suara sendiri dan langsung di simpan ke dalam format audio. Format audio yang disediakan oleh modul voice record adalah format AD4 dan wav. Hasil pengujian modul black box yang diletakkan pada kereta api, dengan mencoba mengucapkan kata  “SAYA”,  suara dapat terekam pada modul perekam suara yang selanjutnya diolah menggunakan ”software sound editor” yang disimpan pada SD Card ber-ekstensi “wav”. Perbandingan sumber suara terhadap jarak penerima dari pengujian didapatkan sebuah persamaan regresi linier  y = -( 31x – 11  dan R² = 0.972.  Pengujian ini menghasilkan penekanan suara dB dan frekuensi sample Hz yang berbeda.  Kata kunci: black box kereta api, perekaman suara, WTR010

The Proteins API: accessing key integrated protein and genome information.

Science.gov (United States)

Nightingale, Andrew; Antunes, Ricardo; Alpi, Emanuele; Bursteinas, Borisas; Gonzales, Leonardo; Liu, Wudong; Luo, Jie; Qi, Guoying; Turner, Edd; Martin, Maria

2017-07-03

The Proteins API provides searching and programmatic access to protein and associated genomics data such as curated protein sequence positional annotations from UniProtKB, as well as mapped variation and proteomics data from large scale data sources (LSS). Using the coordinates service, researchers are able to retrieve the genomic sequence coordinates for proteins in UniProtKB. This, the LSS genomics and proteomics data for UniProt proteins is programmatically only available through this service. A Swagger UI has been implemented to provide documentation, an interface for users, with little or no programming experience, to 'talk' to the services to quickly and easily formulate queries with the services and obtain dynamically generated source code for popular programming languages, such as Java, Perl, Python and Ruby. Search results are returned as standard JSON, XML or GFF data objects. The Proteins API is a scalable, reliable, fast, easy to use RESTful services that provides a broad protein information resource for users to ask questions based upon their field of expertise and allowing them to gain an integrated overview of protein annotations available to aid their knowledge gain on proteins in biological processes. The Proteins API is available at (http://www.ebi.ac.uk/proteins/api/doc). © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

TIC y formación web 2.0 para la inclusión social y el desarrollo sostenible

OpenAIRE

Rosanigo, Zulema Beatriz; Álvarez, Mabel; Paur, Alicia Beatriz; Dans, Marta Isabel; Gallego Gil, Domingo

2012-01-01

En este trabajo se presentan los objetivos y alcances del proyecto de investigación AP/048416/11, “TIC Y Formación Web 2.0 para la Inclusión Social y el Desarrollo Sostenible”, financiado por la Agencia Española de Cooperación Internacional para el Desarrollo (AECID) y en el que participan investigadores de Argentina, Chile, Ecuador y España.

The MPO API: A tool for recording scientific workflows

Energy Technology Data Exchange (ETDEWEB)

Wright, John C., E-mail: jcwright@mit.edu [MIT Plasma Science and Fusion Center, Cambridge, MA (United States); Greenwald, Martin; Stillerman, Joshua [MIT Plasma Science and Fusion Center, Cambridge, MA (United States); Abla, Gheni; Chanthavong, Bobby; Flanagan, Sean; Schissel, David; Lee, Xia [General Atomics, San Diego, CA (United States); Romosan, Alex; Shoshani, Arie [Lawrence Berkeley Laboratory, Berkeley, CA (United States)

2014-05-15

Highlights: • A description of a new framework and tool for recording scientific workflows, especially those resulting from simulation and analysis. • An explanation of the underlying technologies used to implement this web based tool. • Several examples of using the tool. - Abstract: Data from large-scale experiments and extreme-scale computing is expensive to produce and may be used for high-consequence applications. The Metadata, Provenance and Ontology (MPO) project builds on previous work [M. Greenwald, Fusion Eng. Des. 87 (2012) 2205–2208] and is focused on providing documentation of workflows, data provenance and the ability to data-mine large sets of results. While there are important design and development aspects to the data structures and user interfaces, we concern ourselves in this paper with the application programming interface (API) – the set of functions that interface with the data server. Our approach for the data server is to follow the Representational State Transfer (RESTful) software architecture style for client–server communication. At its core, the API uses the POST and GET methods of the HTTP protocol to transfer workflow information in message bodies to targets specified in the URL to and from the database via a web server. Higher level API calls are built upon this core API. This design facilitates implementation on different platforms and in different languages and is robust to changes in the underlying technologies used. The command line client implementation can communicate with the data server from any machine with HTTP access.

The MPO API: A tool for recording scientific workflows

International Nuclear Information System (INIS)

Wright, John C.; Greenwald, Martin; Stillerman, Joshua; Abla, Gheni; Chanthavong, Bobby; Flanagan, Sean; Schissel, David; Lee, Xia; Romosan, Alex; Shoshani, Arie

2014-01-01

Highlights: • A description of a new framework and tool for recording scientific workflows, especially those resulting from simulation and analysis. • An explanation of the underlying technologies used to implement this web based tool. • Several examples of using the tool. - Abstract: Data from large-scale experiments and extreme-scale computing is expensive to produce and may be used for high-consequence applications. The Metadata, Provenance and Ontology (MPO) project builds on previous work [M. Greenwald, Fusion Eng. Des. 87 (2012) 2205–2208] and is focused on providing documentation of workflows, data provenance and the ability to data-mine large sets of results. While there are important design and development aspects to the data structures and user interfaces, we concern ourselves in this paper with the application programming interface (API) – the set of functions that interface with the data server. Our approach for the data server is to follow the Representational State Transfer (RESTful) software architecture style for client–server communication. At its core, the API uses the POST and GET methods of the HTTP protocol to transfer workflow information in message bodies to targets specified in the URL to and from the database via a web server. Higher level API calls are built upon this core API. This design facilitates implementation on different platforms and in different languages and is robust to changes in the underlying technologies used. The command line client implementation can communicate with the data server from any machine with HTTP access

Comportamento de forrageamento de Apis mellifera na melancieira (Citrullus lanatus no município de Juazeiro, BA

Directory of Open Access Journals (Sweden)

Diego Araújo

2014-03-01

Full Text Available Este estudo descreve o comportamentode forrageamento de Apis mellifera, sua frequência e preferência pelos tipos e recursos florais da melancieira. O experimento foi conduzido na UNEB/DTCS, em Juazeiro-BA, nos anos de 2012 e 2013. A variedade de melancieira utilizada foi a Crimson Sweet, desenvolvida em cultivo tradicional. Para a identificação dos visitantes foram realizadas observações em dias não consecutivos no horário das 06:00 h às 13:00 h e foram contabilizados: número de visitas por intervalo de tempo, duração da visita, tipo floral visitado e o recurso forrageado. Os polinizadores efetivos registrados para a cultura foram as abelhas Apis mellifera, com preferência pelas flores masculinas e pelo recurso néctar no primeiro período de avaliação (2012. No segundo período (2013 foi registrada uma mudança, sendo as flores femininas as mais visitadas e no caso das masculinas ocorrendo uma preferência pela coleta de pólen. Foi registrada diferença significativa entre os dois períodos de observação (F1-369= 22,31, p<0,05.  A maior concentração de visitas ocorreu no ano de 2012 e, nos dois períodos, as abelhas permaneceram forrageando as flores femininas por mais tempo que as masculinas. O pico de visitação foi registrado em 2012 no horário das 08:00 h - 09:00 h e em 2013 das 07:00 h - 08:00 h. Após as 13:00 h não foram mais registradas visitas e as flores deram início a senescência.

Reactome Pengine: A web-logic API to the homo sapiens reactome.

Science.gov (United States)

Neaves, Samuel R; Tsoka, Sophia; Millard, Louise A C

2018-03-30

Existing ways of accessing data from the Reactome database are limited. Either a researcher is restricted to particular queries defined by a web application programming interface (API), or they have to download the whole database. Reactome Pengine is a web service providing a logic programming based API to the human reactome. This gives researchers greater flexibility in data access than existing APIs, as users can send their own small programs (alongside queries) to Reactome Pengine. The server and an example notebook can be found at https://apps.nms.kcl.ac.uk/reactome-pengine. Source code is available at https://github.com/samwalrus/reactome-pengine and a Docker image is available at https://hub.docker.com/r/samneaves/rp4/ . samuel.neaves@kcl.ac.uk. Supplementary data are available at Bioinformatics online.

UCB-NE-107 user's manual

International Nuclear Information System (INIS)

Lee, W.W.L.

1989-03-01

The purpose of this manual is to provide users of UCB-NE-107 with the information necessary to use UCB-NE-107 effectively. UCB-NE-107 is a computer code for calculating the fractional rate of readily soluble radionuclides that are released from nuclear waste emplaced in water-saturated porous media. Waste placed in such environments will gradually dissolve. For many species such as actinides and rare earths, the process of dissolution is governed by the exterior flow field, and the chemical reaction rate or leaching rate. However, for readily soluble species such as 135 Cs, 137 Cs, and 129 I, it has been observed that their dissolution rates are rapid. UCB-NE-107 is a code for calculating the release rate at the waste/rock interface, to check compliance with the US Nuclear Regulatory Commission's (USNRC) subsystem performance objective. It is an implementation of the analytic solution given below. 5 refs., 2 figs

Inhibiting DNA methylation alters olfactory extinction but not acquisition learning in Apis cerana and Apis mellifera.

Science.gov (United States)

Gong, Zhiwen; Wang, Chao; Nieh, James C; Tan, Ken

2016-07-01

DNA methylation plays a key role in invertebrate acquisition and extinction memory. Honey bees have excellent olfactory learning, but the role of DNA methylation in memory formation has, to date, only been studied in Apis mellifera. We inhibited DNA methylation by inhibiting DNA methyltransferase (DNMT) with zebularine (zeb) and studied the resulting effects upon olfactory acquisition and extinction memory in two honey bee species, Apis cerana and A. mellifera. We used the proboscis extension reflex (PER) assay to measure memory. We provide the first demonstration that DNA methylation is also important in the olfactory extinction learning of A. cerana. DNMT did not reduce acquisition learning in either species. However, zeb bidirectionally and differentially altered extinction learning in both species. In particular, zeb provided 1h before acquisition learning improved extinction memory retention in A. mellifera, but reduced extinction memory retention in A. cerana. The reasons for these differences are unclear, but provide a basis for future studies to explore species-specific differences in the effects of methylation on memory formation. Copyright © 2016 Elsevier Ltd. All rights reserved.

Hemolymph proteome changes during worker brood development match the biological divergences between western honey bees (Apis mellifera) and eastern honey bees (Apis cerana).

Science.gov (United States)

Feng, Mao; Ramadan, Haitham; Han, Bin; Fang, Yu; Li, Jianke

2014-07-05

Hemolymph plays key roles in honey bee molecule transport, immune defense, and in monitoring the physiological condition. There is a lack of knowledge regarding how the proteome achieves these biological missions for both the western and eastern honey bees (Apis mellifera and Apis cerana). A time-resolved proteome was compared using two-dimensional electrophoresis-based proteomics to reveal the mechanistic differences by analysis of hemolymph proteome changes between the worker bees of two bee species during the larval to pupal stages. The brood body weight of Apis mellifera was significantly heavier than that of Apis cerana at each developmental stage. Significantly, different protein expression patterns and metabolic pathways were observed in 74 proteins (166 spots) that were differentially abundant between the two bee species. The function of hemolymph in energy storage, odor communication, and antioxidation is of equal importance for the western and eastern bees, indicated by the enhanced expression of different protein species. However, stronger expression of protein folding, cytoskeletal and developmental proteins, and more highly activated energy producing pathways in western bees suggests that the different bee species have developed unique strategies to match their specific physiology using hemolymph to deliver nutrients and in immune defense. Our disparate findings constitute a proof-of-concept of molecular details that the ecologically shaped different physiological conditions of different bee species match with the hemolymph proteome during the brood stage. This also provides a starting point for future research on the specific hemolymph proteins or pathways related to the differential phenotypes or physiology.

Bactérias diazotróficas associadas a coqueiros na região de baixada litorânea em Sergipe Diazotroph bacteria associated to coconut palms in a coastal lowland region in Sergipe State, Brazil

Directory of Open Access Journals (Sweden)

Marcelo Ferreira Fernandes

2001-12-01

Full Text Available Objetivou-se neste trabalho, isolar, identificar e quantificar bactérias diazotróficas existentes nas raízes e folhas de coqueiro (híbrido PB121 cultivados na baixada litorânea de Sergipe. As populações de bactérias diazotróficas nesses órgãos foram quantificadas pela técnica do número mais provável (NMP em meios semi-sólidos JNFb e NFb, e identificadas por meio de avaliações microscópicas, culturais e de testes bioquímicos dos sistemas API 20 - E e API 20 - NE. O conteúdo de N em meios semi-sólidos NFb e JNFb foi determinado colorimetricamente, após oito dias de incubação das bactérias, a 32ºC, para estimar a capacidade de fixação biológica dos isolados. Enterobactérias pertencentes ao gênero Enterobacter e bactérias com características semelhantes às do gênero Pseudomonas (pseudomonadas foram predominantes entre os isolados obtidos. As enterobactérias e pseudomonadas isoladas de folhas foram predominantemente endofíticas. Quanto às diazotróficas isoladas de raízes, observou-se predominância de enterobactérias na sua superfície, ao passo que as pseudomonadas ocorreram em proporções semelhantes na superfície e no interior desse órgão. Após oito dias de incubação, os conteúdos de N nos meios com inoculação das bactérias pseudomonadas foram maiores do que nos meios com inoculação das enterobactérias.The aim of this work was to isolate, identify and quantify diazotrophic bacteria existing in roots and leaves of coconut palms (hybrid PB121 grown in a coastal lowland of Sergipe, in Brazil. Diazotrophic populations in these organs were quantified by the most probable number (MNP technique on NFb and JNFb semi-solid media and identified by the evaluation of microscopic, cultural and biochemical characteristics of the isolates. Biochemical characteristics were evaluated using the API 20 - E and API 20 - NE galleries. Nitrogen content in NFb and JNFb semi-solid media inoculated with each of the

Technological impact in steels degree API 5L X-70 for the manufacture of resistant ducts of 36 inches of diameter to the bitter gas; Impacto tecnologico de aceros grado API 5L X-70 para la fabricacion de ductos de 36 pulgadas de diametro resistentes al gas amargo

Energy Technology Data Exchange (ETDEWEB)

Aramburo Perez, G.; Garcia Galan, S.; Perez Campos, R.; Juarez Islas, J.A. [Facultad de Quimica, UNAM, Mexico, D.F. (Mexico)

2004-03-01

Several steel plates in the as-hot rolled plus cooled condition were studied, in order to evaluate the impact of the steelmaking route and the controlled thermomechanical processing plus the cooling media. The steelmaking route to produce the slabs involved the use of 100% sponge iron which was feed into an electric arc furnace, vacuum degassed, ladle treated and continuously cast. After soaking, a controlled thermomechanical processing the resulting steel plates cooled in air showed a banded structure, which sometimes presented a central segregation region. The worst plates with a central segregation region showed intermetallic compounds in it. After modifications of the steelmaking route and the controlled thermomechanical/cooling schedule, a steel plate with a ferritic microstructure plus 0.5% in vol of bainite was obtained. This microstructure together with the resulting mechanical properties, fulfilled the API grade 5LX-70 properties, required by the petroleum industry. [Spanish] Se evaluo el impacto del proceso en la fabricacion de planchones de acero grado APIX-70, asimismo, el proceso de deformacion termomecanico controlado, mas enfriamiento de placas. El proceso para producir los planchones involucra el uso de 100% de hierro esponja, el cual es alimentado a un horno electrico, desgasificado al vacio y colado continuamente. Al planchon resultante se le aplica un programa de laminacion en caliente controlado y a las placas resultantes se le aplica un enfriamiento al aire o acelerado. La mayoria de las placas enfriadas al aire mostraron una estructura bandeada, algunas presentaron una region con segregacion central y otras las segregacion central mas la presencia de intermetalicos. Despues de modificar el proceso de fabricacion del acero, su control termomecanico y su programa de enfriamiento, se obtuvo una placa con una microestructura ferrifica mas un 0.5% en volumen de bainita. Esta microestructura junto con el resultado de sus propiedades mecanicas

Photoionization of Ne8+

Science.gov (United States)

Pindzola, M. S.; Abdel-Naby, Sh. A.; Robicheaux, F.; Colgan, J.

2014-05-01

Single and double photoionization cross sections for Ne8+ are calculated using a non-perturbative fully relativistic time-dependent close-coupling method. A Bessel function expansion is used to include both dipole and quadrupole effects in the radiation field interaction and the repulsive interaction between electrons includes both the Coulomb and Gaunt interactions. The fully correlated ground state of Ne8+ is obtained by solving a time-independent inhomogeneous set of close-coupled equations. Propagation of the time-dependent close-coupled equations yields single and double photoionization cross sections for Ne8+ at energies easily accessible at advanced free electron laser facilities. This work was supported in part by grants from NSF and US DoE. Computational work was carried out at NERSC in Oakland, California, NICS in Knoxville, Tennessee, and OLCF in Oak Ridge, Tennessee.

A new species of Miroculis (Ephemeroptera: Leptophlebiidae from NE Argentina Una nueva especie de Miroculis (Ephemeroptera: Leptophlebiidae del NE de Argentina

Directory of Open Access Journals (Sweden)

Eduardo Domínguez

2007-12-01

Full Text Available The genus Miroculis Edmunds has species described from Brazil, Colombia, Peru, Venezuela and Suriname, with additional records from other countries in northern South America. In this paper, Miroculis (Ommaethus misionensis sp. nov. is described from male and female imagos from Misiones Province, NE Argentina. This constitutes the Southernmost record for the genus.El género Miroculis Edmunds tiene especies registradas en Brasil, Colombia, Perú, Venezuela y Surinam, con registros adicionales de otros países en el norte de América del Sur. En este trabajo se describe la especie Miroculis (Ommaethus misionensis sp. nov. de machos y hembras imago, de la provincia de Misiones, en el Noreste de Argentina, lo que constituye el registro más austral para el género.

Current Status of the MiniBooNE Experiment

OpenAIRE

Ray, H.; collaboration, for the MiniBooNE

2004-01-01

MiniBooNE is an experiment designed to refute or confirm the LSND anti-nu_mu -> anti-nu_e oscillation result. MiniBooNE will look for oscillations of nu_mu -> nu_e in a closed-box appearance analysis. MiniBooNE began collecting data in 2002, and is expected to continue data taking through 2005. Current MiniBooNE results are presented.

Performance Analysis of Different NeQuick Ionospheric Model Parameters

Directory of Open Access Journals (Sweden)

WANG Ningbo

2017-04-01

Full Text Available Galileo adopts NeQuick model for single-frequency ionospheric delay corrections. For the standard operation of Galileo, NeQuick model is driven by the effective ionization level parameter Az instead of the solar activity level index, and the three broadcast ionospheric coefficients are determined by a second-polynomial through fitting the Az values estimated from globally distributed Galileo Sensor Stations (GSS. In this study, the processing strategies for the estimation of NeQuick ionospheric coefficients are discussed and the characteristics of the NeQuick coefficients are also analyzed. The accuracy of Global Position System (GPS broadcast Klobuchar, original NeQuick2 and fitted NeQuickC as well as Galileo broadcast NeQuickG models is evaluated over the continental and oceanic regions, respectively, in comparison with the ionospheric total electron content (TEC provided by global ionospheric maps (GIM, GPS test stations and JASON-2 altimeter. The results show that NeQuickG can mitigate ionospheric delay by 54.2%~65.8% on a global scale, and NeQuickC can correct for 71.1%~74.2% of the ionospheric delay. NeQuick2 performs at the same level with NeQuickG, which is a bit better than that of GPS broadcast Klobuchar model.

Assessment of nutritional resources quality from honeybees (Apis ...

African Journals Online (AJOL)

Several environments were selected, namely a rainforest in. Kisangani ... Keywords: Apis mellifera adansonii, honey, bee bread, quality, nutrition, bee ecology, DRC. INTRODUCTION. Various ...... BKN, Co-Proponent of this work, contributed.

Polymorphic DNA sequences of the fungal honey bee pathogen Ascosphaera apis

DEFF Research Database (Denmark)

Jensen, Annette B; Welker, Dennis L; Kryger, Per

2012-01-01

The pathogenic fungus Ascosphaera apis is ubiquitous in honey bee populations. We used the draft genome assembly of this pathogen to search for polymorphic intergenic loci that could be used to differentiate haplotypes. Primers were developed for five such loci, and the species specificities were...... verified using DNA from nine closely related species. The sequence variation was compared among 12 A. apis isolates at each of these loci, and two additional loci, the internal transcribed spacer of the ribosomal RNA (ITS) and a variable part of the elongation factor 1α (Ef1α). The degree of variation...... was then compared among the different loci, and three were found to have the greatest detection power for identifying A. apis haplotypes. The described loci can help to resolve strain differences and population genetic structures, to elucidate host–pathogen interaction and to test evolutionary hypotheses...

$^{8}$Be, $^{12}$C, $^{16}$O, $^{20}$Ne, $^{24}$Mg, and $^{32}$S nuclei and alpha clustering within a generalized liquid drop model

CERN Document Server

Royer, G; Eudes, P

2015-01-01

The potential energy governing the shape and the entrance and decay channels of the 12 C, 16 O, 20 Ne, 24 Mg, and 32 S 4n-nuclei has been determined within a generalized liquid drop model. Different three-dimensional and planar shapes have been investigated: linear chain, triangle, square, tetrahedron, pentagon, trigonal bipyramid, square pyramid, hexagon, octahedron, octogon and cube. The rms radii of the linear chains are higher than the experimental rms radii of the ground states. The binding energies of the planar shapes at the contact point are lower than the ones of the three-dimensional configurations. The a particle plus A-4 daughter configuration leads always to the lowest potential barrier relatively to the sphere configuration.

Antioxidant, antihyperglycemic, and antidiabetic activity of Apis mellifera bee tea.

Directory of Open Access Journals (Sweden)

Janielle da Silva Melo da Cunha

Full Text Available Diabetes has emerged as one of the largest global epidemics; it is estimated that by 2035, there will be 592 million diabetic people in the world. Brazilian biodiversity and the knowledge of traditional peoples have contributed to the treatment of several diseases, including diabetes. Apis mellifera bee tea is used by indigenous Brazilians to treat diabetes, and this traditional knowledge needs to be recorded and studied.The objective of this study was to record the use and to evaluate the antioxidant, antihyperglycemic, and antidiabetic activity of Apis mellifera bee tea, which is used by the Guarani and Kaiowá indigenous people for the treatment of diabetes. Semi-structured interviews were performed with Guarani and Kaiowá ethnic indigenous people from the State of Mato Grosso do Sul, Brazil, seeking to identify the animal species used for medicinal purposes. For the experimental procedures, tea prepared with macerated Apis mellifera bees was used. In vitro assays were performed to evaluate antioxidant activity; direct free radical scavenging, protection against oxidative hemolysis, lipid peroxidation were evaluated in human erythrocytes and potential in inhibiting the formation of advanced glycation end products (AGEs. In vivo, normoglycemic Swiss male mice treated with Apis mellifera tea (AmT were subjected to the oral glucose tolerance test and compared with control and metformin-treated groups. Diet-induced diabetic mice were treated for 21 days with AmT and evaluated for glycemia and malondialdehyde levels in the blood, liver, nervous system, and eyes. During interviews, the indigenous people described the use of Apis mellifera bee tea for the treatment of diabetes. In in vitro assays, AmT showed direct antioxidant activity and reduced oxidative hemolysis and malondialdehyde generation in human erythrocytes. The AmT inhibited the formation of AGEs by albumin-fructose pathways and methylglyoxal products. In vivo, after oral glucose

Antioxidant, antihyperglycemic, and antidiabetic activity of Apis mellifera bee tea.

Science.gov (United States)

Melo da Cunha, Janielle da Silva; Alfredo, Tamaeh Monteiro; Dos Santos, Jéssica Maurino; Alves Junior, Valter Vieira; Rabelo, Luiza Antas; Lima, Emerson Silva; Boleti, Ana Paula de Araújo; Carollo, Carlos Alexandre; Dos Santos, Edson Lucas; de Picoli Souza, Kely

2018-01-01

Diabetes has emerged as one of the largest global epidemics; it is estimated that by 2035, there will be 592 million diabetic people in the world. Brazilian biodiversity and the knowledge of traditional peoples have contributed to the treatment of several diseases, including diabetes. Apis mellifera bee tea is used by indigenous Brazilians to treat diabetes, and this traditional knowledge needs to be recorded and studied.The objective of this study was to record the use and to evaluate the antioxidant, antihyperglycemic, and antidiabetic activity of Apis mellifera bee tea, which is used by the Guarani and Kaiowá indigenous people for the treatment of diabetes. Semi-structured interviews were performed with Guarani and Kaiowá ethnic indigenous people from the State of Mato Grosso do Sul, Brazil, seeking to identify the animal species used for medicinal purposes. For the experimental procedures, tea prepared with macerated Apis mellifera bees was used. In vitro assays were performed to evaluate antioxidant activity; direct free radical scavenging, protection against oxidative hemolysis, lipid peroxidation were evaluated in human erythrocytes and potential in inhibiting the formation of advanced glycation end products (AGEs). In vivo, normoglycemic Swiss male mice treated with Apis mellifera tea (AmT) were subjected to the oral glucose tolerance test and compared with control and metformin-treated groups. Diet-induced diabetic mice were treated for 21 days with AmT and evaluated for glycemia and malondialdehyde levels in the blood, liver, nervous system, and eyes. During interviews, the indigenous people described the use of Apis mellifera bee tea for the treatment of diabetes. In in vitro assays, AmT showed direct antioxidant activity and reduced oxidative hemolysis and malondialdehyde generation in human erythrocytes. The AmT inhibited the formation of AGEs by albumin-fructose pathways and methylglyoxal products. In vivo, after oral glucose overload, normoglycemic

Antioxidant activity and irritation property of venoms from Apis species.

Science.gov (United States)

Somwongin, Suvimol; Chantawannakul, Panuwan; Chaiyana, Wantida

2018-04-01

Pharmacological effects of bee venom has been reported, however, it has been restricted to the bee venom collected from European honey bee (Apis mellifera). The aim of the present study was to compare the antioxidant activities and irritation properties of venoms collected from four different Apis species in Thailand, which includes Apis cerena (Asian cavity nesting honeybee), Apis florea (dwarf honeybee), Apis dorsata (giant honeybee), and A. mellifera. Melittin content of each bee venom extracts was investigated by using high-performance liquid chromatography. Ferric reducing antioxidant power, 2, 2'-azinobis (3-ethylbenzothiazoline-6-sulfonic acid), and 1, 1-diphenyl-2-picrylhydrazyl assay were used to determine the antioxidant activity, whereas, hen's egg test chorioallantoic membrane assay was used to determine the irritation property of each bee venom extracts. Melittin was the major constituent in all bee venom extracts. The melittin content in A. dorsata, A. mellifera, A. florea, and A. cerena were 95.8 ± 3.2%, 76.5 ± 1.9%, 66.3 ± 8.6%, and 56.8 ± 1.8%, respectively. Bee venom extract from A. dorsata possessed the highest antioxidant activity with the inhibition of 41.1 ± 2.2% against DPPH, Trolox equivalent antioxidant capacity of 10.21 ± 0.74 mM Trolox/mg and equivalent concentration (EC 1 ) of 0.35 ± 0.02 mM FeSO 4 /mg. Bee venom extract from A. mellifera exhibited the highest irritation, followed by A. cerena, A. dorsata, and A. florea, respectively. Melittin was the compound responsible for the irritation property of bee venom extracts since it could induce severe irritation (irritation score was 13.7 ± 0.5, at the concentration of 2 mg/ml). The extract from A. dorsata which possessed the highest antioxidant activity showed no irritation up to the concentration of 0.1 mg/ml. Therefore, bee venom extract from A. dorsata at the concentration not more than 0.1 mg/ml would be suggested for using

Manufacturing Amorphous Solid Dispersions with a Tailored Amount of Crystallized API for Biopharmaceutical Testing.

Science.gov (United States)

Theil, Frank; Milsmann, Johanna; Anantharaman, Sankaran; van Lishaut, Holger

2018-05-07

The preparation of an amorphous solid dispersion (ASD) by dissolving a poorly water-soluble active pharmaceutical ingredient (API) in a polymer matrix can improve the bioavailability by orders of magnitude. Crystallization of the API in the ASD, though, is an inherent threat for bioavailability. Commonly, the impact of crystalline API on the drug release of the dosage form is studied with samples containing spiked crystallinity. These spiked samples possess implicit differences compared to native crystalline samples, regarding size and spatial distribution of the crystals as well as their molecular environment. In this study, we demonstrate that it is possible to grow defined amounts of crystalline API in solid dosage forms, which enables us to study the biopharmaceutical impact of actual crystallization. For this purpose, we studied the crystal growth in fenofibrate tablets over time under an elevated moisture using transmission Raman spectroscopy (TRS). As a nondestructive method to assess API crystallinity in ASD formulations, TRS enables the monitoring of crystal growth in individual dosage forms. Once the kinetic trace of the crystal growth for a certain environmental condition is determined, this method can be used to produce samples with defined amounts of crystallized API. To investigate the biopharmaceutical impact of crystallized API, non-QC dissolution methods were used, designed to identify differences between the various amounts of crystalline materials present. The drug release in the samples manufactured in this fashion was compared to that of samples with spiked crystallinity. In this study, we present for the first time a method for targeted crystallization of amorphous tablets to simulate crystallized ASDs. This methodology is a valuable tool to generate model systems for biopharmaceutical studies on the impact of crystallinity on the bioavailability.

Improvements and extensions to API 618 related to pulsation and mechanical response studies

NARCIS (Netherlands)

Eijk, A.; Smeulers, J.P.M.; Blodgett, L.E.; Smalley, A.J.

1999-01-01

Purchasers of reciprocating compressors need a standard to help ensure reliable installations. The PNEUROP standard evolved in Europe, and the API 618 Standard in the U.S.A. Frequent application and generally good experience, worldwide, have led to four releases of API 618, the last dated June 1995.

Metastable He (n=2) - Ne potential interaction calculation

International Nuclear Information System (INIS)

Rahal, H.

1983-10-01

Diabatic potential terms corresponding to He (2 1 S)-Ne and He (2 3 S)-Ne interactions are calculated. These potentials reproduce the experimental results thermal metastable atom elastic scattering on Ne target. A model which reduces the interaction to a one-electron problem is proposed: the He excited electron. Its interaction with the He + center is reproduced by a ''l'' dependent potential model with a 1/2 behaviour at short range. The electron interaction facing the Ne is described by a l-dependent pseudopotential reproducing with accuracy the electron elastic scattering on a Ne atom. The importance of the corrective term related to the Ne polarizations by the electron and the He + ion is showed in this work. In the modelling problems, the accuracy cannot be better than 0.1 MeV [fr

Physicochemical characterisation and investigation of the bonding mechanisms of API-titanate nanotube composites as new drug carrier systems.

Science.gov (United States)

Sipos, Barbara; Pintye-Hódi, Klára; Kónya, Zoltán; Kelemen, András; Regdon, Géza; Sovány, Tamás

2017-02-25

Titanate nanotube (TNT) has recently been explored as a new carrier material for active pharmaceutical ingredients (API). The aim of the present work was to reveal the physicochemical properties of API-TNT composites, focusing on the interactions between the TNTs and the incorporated APIs. Drugs belonging to different Biopharmaceutical Classification System (BCS) classes were loaded into TNTs: diltiazem hydrochloride (BCS I.), diclofenac sodium (BCS II.), atenolol (BCS III.) and hydrochlorothiazide (BCS IV.). Experimental results demonstrated that it is feasible for spiral cross-sectioned titanate nanotubes to carry drugs and maintain their bioactivity. The structural properties of the composites were characterized by a range of analytical techniques, including FT-IR, DSC, TG-MS, etc. The interactions between APIs and TNTs were identified as electrostatic attractions, mainly dominated by hydrogen bonds. Based on the results, it can be stated that the strength of the association depends on the hydrogen donor strength of the API. The drug release of incorporated APIs was evaluated from compressed tablets and compared to that of pure APIs. Differences noticed in the dissolution profiles due to incorporation showed a correlation with the strength of interactions between the APIs and the TNTs observed in the above analytical studies. Copyright © 2016 Elsevier B.V. All rights reserved.

The DAΦNE cryogenic system

International Nuclear Information System (INIS)

Modena, M.

1997-12-01

The DAΦNE Project utilises superconductivity technology for a total of six superconducting magnets: the two Experiment magnets (KLOE and FINUDA) and the four Compensator Solenoid magnets needed to compensate the magnetic effect of the Experiment magnets on the electron and positron beams. This effect, on beams of 510 MeV (nominal DAΦNE Energy), is expected to be relevant, especially with the aim of achieving a very high luminosity, which is the main target of the Project. The KLOE superconducting magnet has two possible working positions: the first in the DAΦNE Hall, when the Experiment will be in operation, and the second one in the KLOE Assembly Hall. This second position is the first to be utilised for the KLOE magnet Acceptance Test and magnetic field mapping, prior to the mounting of all the experimental apparatus inside the magnet. This note intends to present the DAΦNE Cryogenic System and how the authors have converged to the definition of a common Cryogenic System compatible with all the six superconducting magnets

Binary and ternary fission yields induced by 12C and 20Ne ions on 238U targets

International Nuclear Information System (INIS)

Otto, R.J.

1974-01-01

Evidence for ternary fission of 250 Cf* and 258 No* compound nuclei has been found. Relative cross section data for nuclides with masses between 24 Na and 161 Tb have been determined for 12 C bombardments of natural uranium at laboratory energies of 122 MeV, 113 MeV and 105 MeV. Relative cross section data for 8 nuclides between 24 Na and 66 Ni were sought for 20 Ne bombardments of natural uranium at 150 MeV laboratory energies. The binary fission fragment mass distribution for 238 U( 12 C,f) was determined by analysis of fission fragment recoil collection foils using radiochemical techniques and high resolution gamma ray spectroscopy. The results indicated the existence of a ternary fission branch similar to mass distributions obtained for He induced fission of Th, U, and Pu nuclei at intermediate energies. Comparison of the data with He induced ternary fission data obtained previously in this laboratory indicated an increase in the ternary fission probability with increasing Z 2 /A of the compound nucleus and with excitation energy. A shift of the binary-ternary fission product intersection point to lower mass numbers with increasing Z 2 /A and excitation energy of the compound nucleus was also observed. (Diss. Abstr. Int., B)

Technological properties of kaolin from Para

International Nuclear Information System (INIS)

Hildebrando, E.; Martin-Cortes, G.R.; Esper, F.J.; Wiebeck, H.; Alves Junior, P.; Valenzuela-Diaz, F.R.

2011-01-01

The NE of the State of Para, is notable for its large reserves of kaolin for paper. Kaolin is a mineral composed of hydrated aluminum silicates such as kaolinite and halloysite. The exploitation of these reserves to generate products with higher commercial value, especially in the industries of adsorbents and catalysts, is what motivates the continuous study of technological properties of the Amazon kaolin's. Thus, this paper presents a technological characterization of a sample of kaolin from Para State by X-ray diffraction, SEM - scanning electron microscopy and infrared spectroscopy. The results of preliminary tests indicate that the sample consists for the most part by kaolinite present in low concentrations of quartz and anatase. (author)

Heterosis en la longevidad de obreras Apis mielífera

Directory of Open Access Journals (Sweden)

J. Tello

2001-07-01

Full Text Available Se estimó la media y la heterosis de la longevidad en obreras de abejas Apis mellifera. El expe-rimento fue desarrollado en el Apiario del Departamento de Genética de la Facultad de Medi-cina de la USP-Ribeirão Preto-Brasil y en Jaboticabal-SP, de 03/1997 a 05/1999. Seleccionamos 8 matrices inseminadas del apiário-USP (2africanizadas, 2italianas, 2cárnicasy 2italianas*cárnicos y 2 matrices (grupo-testigo de abejas Africanizadas-Silvestres.

Yrast and high spin states in 22Ne

International Nuclear Information System (INIS)

Szanto, E.M.; Toledo, A.S. de

1982-08-01

High spin states in 22 Ne have been investigated by the reactions 11 B( 13 C,d) 22 Ne and 13 C( 11 B,d) 22 Ne up to E* approximately=19 MeV. Yrast states were observed at 11.02 MeV (8 + ) and 15.46 MeV (10 + ) excitation energy. A backbending in 22 Ne is observed around spin 8 + . The location of high spin states I [pt

Chimeras of Bet v 1 and Api g 1 reveal heterogeneous IgE responses in patients with birch pollen allergy.

Science.gov (United States)

Gepp, Barbara; Lengger, Nina; Bublin, Merima; Hemmer, Wolfgang; Breiteneder, Heimo; Radauer, Christian

2014-07-01

Characterization of IgE-binding epitopes of allergens and determination of their patient-specific relevance is crucial for the diagnosis and treatment of allergy. We sought to assess the contribution of specific surface areas of the major birch pollen allergen Bet v 1.0101 to binding IgE of individual patients. Four distinct areas of Bet v 1 representing in total 81% of its surface were grafted onto the scaffold of its homolog, Api g 1.0101, to yield the chimeras Api-Bet-1 to Api-Bet-4. The chimeras were expressed in Escherichia coli and purified. IgE binding of 64 sera from Bet v 1-sensitized subjects with birch pollen allergy was determined by using direct ELISA. Specificity was assessed by means of inhibition ELISA. rApi g 1.0101, Api-Bet-1, Api-Bet-2, Api-Bet-3, and Api-Bet-4 bound IgE from 44%, 89%, 80%, 78%, and 48% of the patients, respectively. By comparing the amount of IgE binding to the chimeras and to rApi g 1.0101, 81%, 70%, 75%, and 45% of the patients showed significantly enhanced IgE binding to Api-Bet-1, Api-Bet-2, Api-Bet-3, and Api-Bet-4, respectively. The minority (8%) of the sera revealed enhanced IgE binding exclusively to a single chimera, whereas 31% showed increased IgE binding to all 4 chimeras compared with rApi g 1.0101. The chimeras inhibited up to 70% of IgE binding to rBet v 1.0101, confirming the specific IgE recognition of the grafted regions. The Bet v 1-specific IgE response is polyclonal, and epitopes are spread across the entire Bet v 1 surface. Furthermore, the IgE recognition profile of Bet v 1 is highly patient specific. Copyright © 2014 The Authors. Published by Mosby, Inc. All rights reserved.

2He decay from excited states: the 18Ne case

International Nuclear Information System (INIS)

Raciti, G.; Sfienti, C.; De Napoli, M.; Rapisarda, E.; Cardella, G.; Giacoppo, F.

2011-01-01

Two-proton radioactivity studies have been performed on excited states of 18 Ne produced by 20 Ne fragmentation at the FRIBs facility of the Laboratori Nazionali del Sud. The study of the relative-momentum correlations of the two protons allowed to disentangle the diproton, democratic and sequential decay contributions to the 2p emission. In order to extend the study on two-proton decay to other light-masses nuclei, an upgrade of the FRIBs facility is planned. A new configuration of the Fragment Separator would be able to increase the acceptance of the beam line and therefore the yield of the produced radioactive beams. Also the present tagging setup will be modified in view of the gain intensity, in order to sustain the higher foreseen incoming rate. Status and perspectives of the facility will be presented. (author)

Herramientas colaborativas para la Gestión del Conocimiento en la Universidad 2.0 (Collaborative tools for Knowledge Management at the University 2.0

Directory of Open Access Journals (Sweden)

Laidy De Armas Jacomino

2016-03-01

Full Text Available Spanish abstract En el contexto empresarial se presentan a diario múltiples problemas que ya han sido resueltos por otras personas anteriormente. Además se buscan informaciones en el exterior cuando la empresa cuenta con expertos en la materia que pudieran contribuir con su conocimiento y aportar a su capital intelectual. Estas situaciones se evidencian de forma particular en las universidades ya que confluyen diversas ciencias y sectores. Para evitar esto se comienza a implementar la Filosofía 2.0, que evita que se pierda el conocimiento organizacional facilitando la colaboración para compartir información, contactos y recursos entre sus miembros. En el caso de las universidades se acuña el término Universidad 2.0 que está asociado en gran medida al uso de herramientas y conceptos colaborativos de la Web 2.0 en sus procesos formativos y empresariales. Estas herramientas se encuentran enfocadas principalmente en las personas y en brindarles la posibilidad de socializar lo que saben convirtiéndose en participantes activos en la construcción y divulgación de nuevo conocimiento. En el presente trabajo se abordan los términos Web 2.0, Empresa 2.0 y Universidad 2.0, así como la marcada relación entre ellos. Además se da a conocer la evolución de la universidad hacia el trabajo colaborativo a través de la Web. Se muestran también herramientas colaborativas que apoyan la Gestión del Conocimiento en la Universidad 2.0. Por último, se proponen un grupo de ideas para la implantación de la Gestión del Conocimiento a través de herramientas colaborativas de la Web en una universidad cubana. English abstract In business context recurrent problems appear. In addition, information outside the organization are searched when the company has experts in the field who could contribute their knowledge and intellectual capital. These situations are particularly evident in the universities which converge various sciences and sectors. To avoid

Using Map Service API for Driving Cycle Detection for Wearable GPS Data: Preprint

Energy Technology Data Exchange (ETDEWEB)

Zhu, Lei [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Gonder, Jeffrey D [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

2017-12-06

Following advancements in smartphone and portable global positioning system (GPS) data collection, wearable GPS data have realized extensive use in transportation surveys and studies. The task of detecting driving cycles (driving or car-mode trajectory segments) from wearable GPS data has been the subject of much research. Specifically, distinguishing driving cycles from other motorized trips (such as taking a bus) is the main research problem in this paper. Many mode detection methods only focus on raw GPS speed data while some studies apply additional information, such as geographic information system (GIS) data, to obtain better detection performance. Procuring and maintaining dedicated road GIS data are costly and not trivial, whereas the technical maturity and broad use of map service application program interface (API) queries offers opportunities for mode detection tasks. The proposed driving cycle detection method takes advantage of map service APIs to obtain high-quality car-mode API route information and uses a trajectory segmentation algorithm to find the best-matched API route. The car-mode API route data combined with the actual route information, including the actual mode information, are used to train a logistic regression machine learning model, which estimates car modes and non-car modes with probability rates. The experimental results show promise for the proposed method's ability to detect vehicle mode accurately.

One-neutron knockout from Ne24-28 isotopes

CERN Document Server

Rodriguez-Tajes, C; Caamano, M; Faestermann, T; Cortina-Gil, D; Zhukov, M; Simon, H; Nilsson, T; Borge, M J G; Alvarez-Pol, H; Winkler, M; Prochazka, A; Nociforo, C; Weick, H; Kanungo, R; Perez-Loureiro, D; Kurtukian, T; Suemmerer, K; Eppinger, K; Perea, A; Chatillon, A; Maierbeck, P; Benlliure, J; Pascual-Izarra, C; Gernhaeuser, R; Geissel, H; Aumann, T; Kruecken, R; Larsson, K; Tengblad, O; Benjamim, E; Jonson, B; Casarejos, E

2010-01-01

One-neutron knockout reactions of Ne24-28 in a beryllium target have been studied in the Fragment Separator (FRS), at GSI. The results include inclusive one-neutron knockout cross-sections as well as longitudinal-momentum distributions of the knockout fragments. The ground-state structure of the neutron-rich neon isotopes was obtained from an analysis of the measured momentum distributions. The results indicate that the two heaviest isotopes, Ne-27 and Ne-28, are dominated by a configuration in which a s(1/2) neutron is coupled to an excited state of the Ne-26 and Ne-27 core, respectively. (C) 2010 Elsevier B.V. All rights reserved.

Learning Bing maps API

CERN Document Server

Sinani, Artan

2013-01-01

This is a practical, hands-on guide with illustrative examples, which will help you explore the vast universe of Bing maps.If you are a developer who wants to learn how to exploit the numerous features of Bing Maps then this book is ideal for you. It can also be useful for more experienced developers who wish to explore other areas of the APIs. It is assumed that you have some knowledge of JavaScript, HTML, and CSS. For some chapters a working knowledge of .Net and Visual Studio is also needed.

Open Astronomy Catalogs API

Science.gov (United States)

Guillochon, James; Cowperthwaite, Philip S.

2018-05-01

We announce the public release of the application program interface (API) for the Open Astronomy Catalogs (OACs), the OACAPI. The OACs serve near-complete collections of supernova, tidal disruption, kilonova, and fast stars data (including photometry, spectra, radio, and X-ray observations) via a user-friendly web interface that displays the data interactively and offers full data downloads. The OACAPI, by contrast, enables users to specifically download particular pieces of the OAC dataset via a flexible programmatic syntax, either via URL GET requests, or via a module within the astroquery Python package.

Tests of Lorentz and CPT violation with MiniBooNE neutrino oscillation excesses

International Nuclear Information System (INIS)

Katori, Teppei

2014-01-01

Lorentz and CPT symmetry violaton is a predicted phenomenon of Planck–scale physics. Various types of data are analyzed to search for Lorentz violation under the Standard–Model Extension (SME) framework, including neutrino oscillation data. MiniBooNE is a short–baseline neutrino oscillation experiment at Fermilab. The measured excesses from MiniBooNE cannot be reconciled within the neutrino Standard Model (vSM); thus it might be a signal of new physics, such as Lorentz violation. We have analyzed the sidereal time dependence of MiniBooNE data for signals of the possible sidereal time dependence of the ocillation signals. we find that the v e appearance data prefer a sidereal time–independent solution, and the v-bar e appearance data slightly prefer a sidereal time–dependent solution, however, the statistical significance is not high to claim the discovery. Limits of order 10 −20 GeV are placed on combinations of SME coefficients

OSCAR API for Real-Time Low-Power Multicores and Its Performance on Multicores and SMP Servers

Science.gov (United States)

Kimura, Keiji; Mase, Masayoshi; Mikami, Hiroki; Miyamoto, Takamichi; Shirako, Jun; Kasahara, Hironori

OSCAR (Optimally Scheduled Advanced Multiprocessor) API has been designed for real-time embedded low-power multicores to generate parallel programs for various multicores from different vendors by using the OSCAR parallelizing compiler. The OSCAR API has been developed by Waseda University in collaboration with Fujitsu Laboratory, Hitachi, NEC, Panasonic, Renesas Technology, and Toshiba in an METI/NEDO project entitled "Multicore Technology for Realtime Consumer Electronics." By using the OSCAR API as an interface between the OSCAR compiler and backend compilers, the OSCAR compiler enables hierarchical multigrain parallel processing with memory optimization under capacity restriction for cache memory, local memory, distributed shared memory, and on-chip/off-chip shared memory; data transfer using a DMA controller; and power reduction control using DVFS (Dynamic Voltage and Frequency Scaling), clock gating, and power gating for various embedded multicores. In addition, a parallelized program automatically generated by the OSCAR compiler with OSCAR API can be compiled by the ordinary OpenMP compilers since the OSCAR API is designed on a subset of the OpenMP. This paper describes the OSCAR API and its compatibility with the OSCAR compiler by showing code examples. Performance evaluations of the OSCAR compiler and the OSCAR API are carried out using an IBM Power5+ workstation, an IBM Power6 high-end SMP server, and a newly developed consumer electronics multicore chip RP2 by Renesas, Hitachi and Waseda. From the results of scalability evaluation, it is found that on an average, the OSCAR compiler with the OSCAR API can exploit 5.8 times speedup over the sequential execution on the Power5+ workstation with eight cores and 2.9 times speedup on RP2 with four cores, respectively. In addition, the OSCAR compiler can accelerate an IBM XL Fortran compiler up to 3.3 times on the Power6 SMP server. Due to low-power optimization on RP2, the OSCAR compiler with the OSCAR API

CHEMICAL COMPOSITION AND ANTIOXIDANT ACTIVITY OF APIS ...

African Journals Online (AJOL)

CHEMICAL COMPOSITION AND ANTIOXIDANT ACTIVITY OF APIS. MELLIFERA BEE POLLEN FROM NORTHWEST ALGERIA. A. Rebiai* and T.Lanez. University of El Oued, VTRS Laboratory, P.O. Box 789, 39000, El Oued, Algeria. Received: 08 November 2012 / Accepted: 23 December 2012 / Published online: 31 ...

Desarrollo de funciones de índice de sitio para Eucalyptus grandis cultivado en la Mesopotamia argentina

Directory of Open Access Journals (Sweden)

CRECHI, E.H

2011-12-01

Full Text Available ResumenSe desarrollaron modelos para la estimación del índice de sitio para Eucalyptus grandis implantado en la Mesopotamia argentina. Dicha estimación se llevó a cabo a través de la evaluación de una base general de datos que contó con 106 parcelas (439 mediciones, de las cuales 48 (197 mediciones pertenecían a la zona Misiones-NE Corrientes y 58 (242 mediciones a la zona Concordia-Monte Caseros (NE Entre Ríos-SE Corrientes. Analizadas las curvas promedio de evolución de la altura dominante con la edad de las dos regiones agroecológicas consideradas, se observó que sus pendientes diferían por lo que se ajustaron funciones de sitio para cada una de ellas. Fueron empleados tres métodos tradicionales, curva guía, reparametrización y ecuaciones diferenciales. El procedimiento elegido dependió de la calidad de información disponible en las zonas agroecológicas bajo estudio, aunque se priorizó que cumplieran con algunos criterios deseables para las funciones de sitio como el polimorfismo y que las alturas sean invariantes respecto de la edad índice, entre otros criterios, como también la de estabilidad frente a sus propios datos. Para la zona agro-ecológica Misiones-NE Corrientes se lograron buenos ajustes con el método de la curva Guía, mientras que para la zona Concordia-Monte Caseros se optó por el modelo de Schumacher ajustado mediante el método de aproximación algebraica diferencial (ADA.AbstractEquations for the prediction of site index of Eucalyptus grandis planted in the Mesopotamia region of Argentina, were developed. With this purpose a data base with 106 plots (439 pairs age-hdom was used; of it 48 (197 pairs age-Hdom belongs to Misiones-NE Corrientes agro ecological zone and the other 58 plots (242 pairs age-hdom belongs to the zone Concordia-Monte Caseros (SE Corrientes – NE Entre Ríos. Analyzed the evolution of the relationship between age-hdom of both zones it was determined that the slopes of the models

Variation morphogeometrics of Africanized honey bees (Apis mellifera in Brazil

Directory of Open Access Journals (Sweden)

Lorena A. Nunes

2012-09-01

Full Text Available The morphometrics of the honey bee Apis mellifera L., 1758 has been widely studied mainly because this species has great ecological importance, high adaptation capacity, wide distribution and capacity to effectively adapt to different regions. The current study aimed to investigate the morphometric variations of wings and pollen baskets of honey bees Apis mellifera scutellata Lepeletier, 1836 from the five regions in Brazil. We used geometric morphometrics to identify the existence of patterns of variations of shape and size in Africanized honey bees in Brazil 16 years after the classic study with this species, allowing a temporal and spatial comparative analysis using new technological resources to assess morphometrical data. Samples were collected in 14 locations in Brazil, covering the five geographical regions of the country. The shape analysis and multivariate analyses of the wing allowed to observe that there is a geographical pattern among the population of Apis mellifera in Brazil. The geographical variations may be attributed to the large territorial extension of the country in addition to the differences between the bioregions.

Carbonic anhydrase from Apis mellifera: purification and inhibition by pesticides.

Science.gov (United States)

Soydan, Ercan; Güler, Ahmet; Bıyık, Selim; Şentürk, Murat; Supuran, Claudiu T; Ekinci, Deniz

2017-12-01

Carbonic anhydrase (CA) enzymes have been shown to play an important role in ion transport and in pH regulation in several organisms. Despite this information and the wealth of knowledge regarding the significance of CA enzymes, few studies have been reported about bee CA enzymes and the hazardous effects of chemicals. Using Apis mellifera as a model, this study aimed to determine the risk of pesticides on Apis mellifera Carbonic anhydrase enzyme (Am CA). CA was initially purified from Apis mellifera spermatheca for the first time in the literature. The enzyme was purified with an overall purification of ∼35-fold with a molecular weight of ∼32 kDa. The enzyme was then exposed to pesticides, including tebuconazole, propoxur, carbaryl, carbofuran, simazine and atrazine. The six pesticides dose-dependently inhibited in vitro AmCA activity at low micromolar concentrations. IC 50 values for the pesticides were 0.0030, 0.0321, 0.0031, 0.0087, 0.0273 and 0.0165 μM, respectively. The AmCA inhibition mechanism of these compounds is unknown at this moment.

PyPDB: a Python API for the Protein Data Bank.

Science.gov (United States)

Gilpin, William

2016-01-01

We have created a Python programming interface for the RCSB Protein Data Bank (PDB) that allows search and data retrieval for a wide range of result types, including BLAST and sequence motif queries. The API relies on the existing XML-based API and operates by creating custom XML requests from native Python types, allowing extensibility and straightforward modification. The package has the ability to perform many types of advanced search of the PDB that are otherwise only available through the PDB website. PyPDB is implemented exclusively in Python 3 using standard libraries for maximal compatibility. The most up-to-date version, including iPython notebooks containing usage tutorials, is available free-of-charge under an open-source MIT license via GitHub at https://github.com/williamgilpin/pypdb, and the full API reference is at http://williamgilpin.github.io/pypdb_docs/html/. The latest stable release is also available on PyPI. wgilpin@stanford.edu. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Construction and assembly of pipelines using API 5L grade X80 tubes - considerations to be observed with high-strength steels; Construcao e montagem de dutos terrestres utilizando tubos API 5L Gr. X80

Energy Technology Data Exchange (ETDEWEB)

Oliveira, Ailton C. de; Rabello, Jose Mauricio B. [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil)

2005-07-01

The use of line pipes API 5L Grade X80, at the point of view of designer allows: reduction of wall thickness and pipe weight or increase of design pressure. In the pipeline construction point of view, the use of line pipes API 5L Grade X80 provide some advantages, however some difficulties must be expected in several stages of the construction and assembly. The implications in cost, productivity, inspection and integrity, with the application of these high resistance steels, complying with PETROBRAS Standard N - 464 Construcao, Montagem e Condicionamento de Dutos Terrestres (Rev. H - 2004 Dec) and the experience consolidated in pipelines construction abroad were presented. At the design stage, a comparison between pipelines designed using API 5L-X70 and API 5L-X80 was carried out approaching the aspects of variation of thickness, pressure design and design factor. An evaluation of the expected gains when choosing API 5L Grade X80 steels were done, regarding reduction of costs and pipe weight. Regarding API 5L-X80 pipe fabrication, the obtained results were reported, proving that this aspect was already overcome, showing the viability of its production in Brazil. Difficulties were detected regarding construction and assembly stage and showing the need of revision of PETROBRAS standard N-464. (author)

Herramienta ALTER. Recursos educativos digitales en red y actividades con herramientas Web 2.0 para aulas hospitalarias

OpenAIRE

Serrano Sánchez, José Luis; Torres Soto, Ana

2012-01-01

Serrano, J.L. y Torres, A. (2012). Herramienta ALTER. Recursos educativos digitales en red y actividades con herramientas Web 2.0 para aulas hospitalarias. En M.P. Prendes y J.L. Serrano (Coords.), Las TIC en las aulas hospitalarias. Alicante: Marfil.

Towards Standardized Patient Data Exchange: Integrating a FHIR Based API for the Open Medical Record System.

Science.gov (United States)

Kasthurirathne, Suranga N; Mamlin, Burke; Grieve, Grahame; Biondich, Paul

2015-01-01

Interoperability is essential to address limitations caused by the ad hoc implementation of clinical information systems and the distributed nature of modern medical care. The HL7 V2 and V3 standards have played a significant role in ensuring interoperability for healthcare. FHIR is a next generation standard created to address fundamental limitations in HL7 V2 and V3. FHIR is particularly relevant to OpenMRS, an Open Source Medical Record System widely used across emerging economies. FHIR has the potential to allow OpenMRS to move away from a bespoke, application specific API to a standards based API. We describe efforts to design and implement a FHIR based API for the OpenMRS platform. Lessons learned from this effort were used to define long term plans to transition from the legacy OpenMRS API to a FHIR based API that greatly reduces the learning curve for developers and helps enhance adhernce to standards.

Absorbed dose to water comparison between NE 2561 and NE 2671 chambers using IAEA, HPA and NACP protocols for gamma ray beam

International Nuclear Information System (INIS)

Mohd Taufik Dolah; Noriah Mod Ali; Taiman Kadni

2002-01-01

The aim of this study to evaluate the performance of NE 2571 chamber in comparison with NE 2561 chamber in determination of the absorbed dose to water in gamma ray beam. In this study NE 2561 is taking as a reference standard chamber while NE 2571 as a working standard. Irradiation of chamber (alternately) was performed at a reference depth, 5 cm, inside the IAEA water phantom. Both chambers were exposed to 13 difference exposures of gamma rays. The values of absorbed dose to water were then determined using IAEA, HPA and NACP protocols. Deviations of absorbed dose determined by NE 2561 and NE 2571 were calculated for each protocol. result obtained in terms of [protocol, μ (mean deviation) ± σ s e (standard error)] were (IAEA, 1.12 ± 0.04], [HPA, 0.09 ± 0.04], and [NCP, 0.09 ± 0.04]. It can be concluded that NE 2571 shown acceptable performance as it is within acceptable limit ± 3%. (Author)

The SEMAINE API: Towards a Standards-Based Framework for Building Emotion-Oriented Systems

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Marc Schröder

2010-01-01

Full Text Available This paper presents the SEMAINE API, an open source framework for building emotion-oriented systems. By encouraging and simplifying the use of standard representation formats, the framework aims to contribute to interoperability and reuse of system components in the research community. By providing a Java and C++ wrapper around a message-oriented middleware, the API makes it easy to integrate components running on different operating systems and written in different programming languages. The SEMAINE system 1.0 is presented as an example of a full-scale system built on top of the SEMAINE API. Three small example systems are described in detail to illustrate how integration between existing and new components is realised with minimal effort.

First identification of nanoparticles on thorax, abdomen and wings of the worker bee Apis dorsata Fabricius

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Bhattacharyya Atanu

2016-06-01

Full Text Available The presence of nanoparticles on the body of the honeybee Apis dorsata Fabricius, was investigated for the first time to better understand the bee’s behaviour. These have been observed by using Scanning Electron Microscopy (SEM, Transmission Electron Microscopy (TEM and confirmed by Atomic Force Microscopy (AFM. Our study clearly denotes that the Indian rock honey bee Apis dorsata possess calcium silicate and calcium phosphate nanoparticles on its body surface of 5-50 nm in diameter. In particular, the nanoparticles on the abdomen and thorax of A. dorsata have an average diameter of about 10 nanometers and they are smaller than those found on wings of the same bees which are about 20 nanometers. The nanoparticles found are different of the ones previously observed on honey bees or other insects. The origin and role of these natural nanoparticles on the body of the Indian rock bee need to be to be further investigated; more research in the subject might raise important aspects in relation to the conservation of these unique pollinators.

Steroid Hormone (20-Hydroxyecdysone) Modulates the Acquisition of Aversive Olfactory Memories in Pollen Forager Honeybees

Science.gov (United States)

Geddes, Lisa H.; McQuillan, H. James; Aiken, Alastair; Vergoz, Vanina; Mercer, Alison R.

2013-01-01

Here, we examine effects of the steroid hormone, 20-hydroxyecdysone (20-E), on associative olfactory learning in the honeybee, "Apis mellifera." 20-E impaired the bees' ability to associate odors with punishment during aversive conditioning, but did not interfere with their ability to associate odors with a food reward (appetitive…

Hymenoptera venom review focusing on Apis mellifera

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P. R. de Lima

2003-01-01

Full Text Available Hymenoptera venoms are complex mixtures containing simple organic molecules, proteins, peptides, and other bioactive elements. Several of these components have been isolated and characterized, and their primary structures determined by biochemical techniques. These compounds are responsible for many toxic or allergic reactions in different organisms, such as local pain, inflammation, itching, irritation, and moderate or severe allergic reactions. The most extensively characterized Hymenoptera venoms are bee venoms, mainly from the Apis genus and also from social wasps and ant species. However, there is little information about other Hymenoptera groups. The Apis venom presents high molecular weight molecules - enzymes with a molecular weight higher than 10.0 kDa - and peptides. The best studied enzymes are phospholipase A2, responsible for cleaving the membrane phospholipids, hyaluronidase, which degrades the matrix component hyaluronic acid into non-viscous segments and acid phosphatase acting on organic phosphates. The main peptide compounds of bee venom are lytic peptide melittin, apamin (neurotoxic, and mastocyte degranulating peptide (MCD.

Investigating an API for resilient exascale computing.

Energy Technology Data Exchange (ETDEWEB)

Stearley, Jon R.; Tomkins, James; VanDyke, John P.; Ferreira, Kurt Brian; Laros, James H.,; Bridges, Patrick

2013-05-01

Increased HPC capability comes with increased complexity, part counts, and fault occurrences. In- creasing the resilience of systems and applications to faults is a critical requirement facing the viability of exascale systems, as the overhead of traditional checkpoint/restart is projected to outweigh its bene ts due to fault rates outpacing I/O bandwidths. As faults occur and propagate throughout hardware and software layers, pervasive noti cation and handling mechanisms are necessary. This report describes an initial investigation of fault types and programming interfaces to mitigate them. Proof-of-concept APIs are presented for the frequent and important cases of memory errors and node failures, and a strategy proposed for lesystem failures. These involve changes to the operating system, runtime, I/O library, and application layers. While a single API for fault handling among hardware and OS and application system-wide remains elusive, the e ort increased our understanding of both the mountainous challenges and the promising trailheads. 3

The Matchmaker Exchange API: automating patient matching through the exchange of structured phenotypic and genotypic profiles.

Science.gov (United States)

Buske, Orion J; Schiettecatte, François; Hutton, Benjamin; Dumitriu, Sergiu; Misyura, Andriy; Huang, Lijia; Hartley, Taila; Girdea, Marta; Sobreira, Nara; Mungall, Chris; Brudno, Michael

2015-10-01

Despite the increasing prevalence of clinical sequencing, the difficulty of identifying additional affected families is a key obstacle to solving many rare diseases. There may only be a handful of similar patients worldwide, and their data may be stored in diverse clinical and research databases. Computational methods are necessary to enable finding similar patients across the growing number of patient repositories and registries. We present the Matchmaker Exchange Application Programming Interface (MME API), a protocol and data format for exchanging phenotype and genotype profiles to enable matchmaking among patient databases, facilitate the identification of additional cohorts, and increase the rate with which rare diseases can be researched and diagnosed. We designed the API to be straightforward and flexible in order to simplify its adoption on a large number of data types and workflows. We also provide a public test data set, curated from the literature, to facilitate implementation of the API and development of new matching algorithms. The initial version of the API has been successfully implemented by three members of the Matchmaker Exchange and was immediately able to reproduce previously identified matches and generate several new leads currently being validated. The API is available at https://github.com/ga4gh/mme-apis. © 2015 WILEY PERIODICALS, INC.

Breaking of the neutron magic number N=20 in 32Mg and 30Ne and its possible relation to the cluster structure

International Nuclear Information System (INIS)

Kimura, Masaaki; Horiuchi, Hisashi

2002-01-01

The neutron-rich nuclei 32 Mg and 30 Ne are studied using a new version of antisymmetrized molecular dynamics (AMD). Due to the use of a deformed Gaussian as the single particle wave packet, the description of the deformation properties of Mg isotopes is drastically improved, and l·s force is accounted for more largely and sufficiently. After the angular momentum projection, 32 Mg and 30 Ne have deformed ground states, and the experimental data for 32 Mg are reproduced with reasonable accuracy. The deformation of the mean field is found to be essential to describe these nuclei. The ground states of these nuclei have neutron 2p2h structure. In 30 Ne, the cluster-like and the mean-field-like structures coexist. The ground state of 32 Mg has a mean-field-like structure. In the vicinity of the ground state, this nucleus is expected to have excited states with cluster-like structure that possesses the neutron 4p4h configuration. (author)

ETIČNE DILEME PODJETNIKA

OpenAIRE

Cvek, Tadej

2010-01-01

Etika in morala se skozi čas nenehno spreminjata in nekatere stvari, ki so danes nedovoljene, so bile še pred kratkim dovoljene in obratno. Razlog za to so predvsem družbene in kulturne spremembe, ki vodijo do drugačnih pogledov na stvari in okolico. Skladno z razvojem etike in morale, se razvijajo tudi nove etične teorije, ki še ne dosegajo starejših teorij a vendarle pridobivajo na pomembnosti in kdo ve, mogoče jih bodo kdaj v prihodnosti tudi presegle. Za MNP je pomembno, da razlikuje...

The novel Akt inhibitor API-1 induces c-FLIP degradation and synergizes with TRAIL to augment apoptosis independent of Akt inhibition.

Science.gov (United States)

Li, Bo; Ren, Hui; Yue, Ping; Chen, Mingwei; Khuri, Fadlo R; Sun, Shi-Yong

2012-04-01

API-1 (pyrido[2,3-d]pyrimidines) is a novel small-molecule inhibitor of Akt, which acts by binding to Akt and preventing its membrane translocation and has promising preclinical antitumor activity. In this study, we reveal a novel function of API-1 in regulation of cellular FLICE-inhibitory protein (c-FLIP) levels and TRAIL-induced apoptosis, independent of Akt inhibition. API-1 effectively induced apoptosis in tested cancer cell lines including activation of caspase-8 and caspase-9. It reduced the levels of c-FLIP without increasing the expression of death receptor 4 (DR4) or DR5. Accordingly, it synergized with TRAIL to induce apoptosis. Enforced expression of ectopic c-FLIP did not attenuate API-1-induced apoptosis but inhibited its ability to enhance TRAIL-induced apoptosis. These data indicate that downregulation of c-FLIP mediates enhancement of TRAIL-induced apoptosis by API-1 but is not sufficient for API-1-induced apoptosis. API-1-induced reduction of c-FLIP could be blocked by the proteasome inhibitor MG132. Moreover, API-1 increased c-FLIP ubiquitination and decreased c-FLIP stability. These data together suggest that API-1 downregulates c-FLIP by facilitating its ubiquitination and proteasome-mediated degradation. Because other Akt inhibitors including API-2 and MK2206 had minimal effects on reducing c-FLIP and enhancement of TRAIL-induced apoptosis, it is likely that API-1 reduces c-FLIP and enhances TRAIL-induced apoptosis independent of its Akt-inhibitory activity. 2012 AACR

Study of proton and 2 protons emission from light neutron deficient nuclei around A=20

International Nuclear Information System (INIS)

Zerguerras, T.

2001-09-01

Proton and two proton emission from light neutron deficient nuclei around A=20 have been studied. A radioactive beam of 18 Ne, 17 F and 20 Mg, produced at the Grand Accelerateur National d'Ions Lourds by fragmentation of a 24 Mg primary beam at 95 MeV/A, bombarded a 9 Be target to form unbound states. Proton(s) and nuclei from the decay were detected respectively in the MUST array and the SPEG spectrometer. From energy and angle measurements, the invariant mass of the decaying nucleus could be reconstructed. Double coincidence events between a proton and 17 F, 16 O, 15 O, 14 O and 18 Ne were registered to obtain excitation energy spectra of 18 Ne, 17 F, 16 F, 15 F et 19 Na. Generally, the masses measures are in agreement with previous experiments. In the case of 18 Ne, excitation energy and angular distributions agree well with the predictions of a break up model calculation. From 17 Ne proton coincidences, a first experimental measurement of the ground state mass excess of 18 Na has been obtained and yields 24,19(0,15)MeV. Two proton emission from 17 Ne and 18 Ne excited states and the 19 Mg ground state was studied through triple coincidences between two proton and 15 O, 16 O and 17 Ne respectively. In the first case, the proton-proton relative angle distribution in the center of mass has been compared with model calculation. Sequential emission from excited states of 17 Ne, above the proton emission threshold, through 16 F is dominant but a 2 He decay channel could not be excluded. No 2 He emission from the 1.288 MeV 17 Ne state, or from the 6.15 MeV 18 Ne state has been observed. Only one coincidence event between 17 Ne and two proton was registered, the value of the one neutron stripping reaction cross section of 20 Mg being much lower than predicted. (author)

Status of the KM3NeT project

International Nuclear Information System (INIS)

Katz, U.F.

2009-01-01

KM3NeT is a future research infrastructure in the Mediterranean Sea, hosting a cubic-kilometre scale neutrino telescope and nodes for associated sciences such as marine biology, oceanology and geophysics. The status of the KM3NeT project and the progress made in the EU-funded Design Study is reviewed. Some physics studies indicating the sensitivity of the KM3NeT neutrino telescope are highlighted and selected major technical design options to be further pursued are described. Finally, the remaining steps towards construction of KM3NeT will be discussed. This document reflects the status of the KM3NeT Conceptual Design Report (CDR), which has been presented to the public for the first time at the VLVnT08 Workshop.

pH and Heat Resistance of the Major Celery Allergen Api g 1.

Science.gov (United States)

Rib-Schmidt, Carina; Riedl, Philipp; Meisinger, Veronika; Schwaben, Luisa; Schulenborg, Thomas; Reuter, Andreas; Schiller, Dirk; Seutter von Loetzen, Christian; Rösch, Paul

2018-05-25

The major celery allergen Api g 1 is a member of the pathogenesis-related 10 class protein family. Here we aimed to investigate the impact of heat and pH on the native protein conformation required for Immunoglobulin E (IgE) recognition. Spectroscopic methods, MS and IgE binding analyses were used to study the effects of pH and thermal treatment on Api g 1.0101. Heat processing results in a loss of the native protein fold via denaturation, oligomerisation and precipitation along with a subsequent reduction of IgE recognition. The induced effects and timescales are strongly pH depended. While Api g 1 refolds partially into an IgE-binding conformation at physiological pH, acidic pH treatment leads to the formation of structurally heat resistant, IgE-reactive oligomers. Thermal processing in the presence of a celery matrix or at pH conditions close to the isoelectric point (pI = 4.63) of Api g 1.0101 results in almost instant precipitation. Our data demonstrate that Api g 1.0101 is not intrinsically susceptible to heat treatment in vitro. However, the pH and the celery matrix strongly influence the stability of Api g 1.0101 and might be the main reasons for the observed temperature lability of this important food allergen. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Desempenho em Pastagens e Características de Carcaça da 16a Progênie dos Rebanhos Nelore, Guzerá e Caracu de Sertãozinho (SP

Directory of Open Access Journals (Sweden)

Razook Alexander George

2002-01-01

Full Text Available Quarenta e um machos inteiros dos rebanhos selecionados para peso aos 378 dias (P378, nascidos em 1996, foram terminados em pastagens de Panicum Maximum (Jacq., Panicum Maximum (Jaq cv. Tanzania 1 e Brachiaria brizantha (Hoschst Stapf cv. Marandu na Estação Experimental de Zootecnia de Sertãozinho (SP. As amostras, representando a média de P378 em cada rebanho, foram: 11 animais Nelore Seleção (NeS e 10 para cada um dos grupos Nelore Controle (NeC, Guzerá Seleção (GuS e Caracu (Ca. O abate ocorreu aos 824 dias de idade e condição corporal 7,6, em uma escala de 1 a 9. As médias mínimas e máximas ajustadas, para as principais características, considerando-se todos os grupos, foram: ganho de peso médio diário, 406 (NeC e 501 g (NeS; peso de abate (PAB, 446,8 (NeC e 544,3 kg (NeS ; peso de carcaça (PCAR, 249,8 (NeC e 309,7 kg (NeS; rendimento de carcaça (REND, 54,0 (GuS e 56,3% (NeC e NeS. No corte entre a 9feminine e 11feminine costelas : músculo 59,6 (NeC e 65,2% (Ca; gordura, 15,6 (Ca e 21,4% (NeC; osso, 18,9 (NeC e 20,2% (GuS; espessura de gordura (ESPGOR, 2,0 (Ca e 4,2 mm (NeC; área de olho de lombo (AOL, 65,6 (NeC e 71,1 cmsuperscript two (NeS e Ca; força de cisalhamento (FC, 4,5 (Ca e 6,6 kg (GuS e perdas totais no cozimento (PERDAS, 22,5 (NeC e 24,9% (GuS. A seleção para peso provocou, em NeS, maiores PAB e PCAR, sem interferir no REND, na composição da costela, FC e PERDAS na carne. Houve, porém, menor ESPGOR em relação à NeC. Os animais GuS apresentaram PAB e PCAR intermediários, entre NeS e Ca, e menor REND e os Ca maior proporção de músculo na costela e carne com maior maciez em relação ao Zebu.

Fast neutron emission in the interaction of 9 MeV/nucleon 12C and 20Ne ions with 181Ta nuclei

International Nuclear Information System (INIS)

Kozulin, Eh.M.; Blinov, M.V.; Kovalenko, S.S.; Mozhaev, A.N.; Borcha, K.; Penionzhkevich, Yu.Eh.

1987-01-01

Energy spectra and angular distributions have been measured for neutrons emitted from the 12 C(105 MeV)+ 181 Ta and 20 Ne(180 MeV)+ 181 Ta reactions. The obtained experimental data suggest a conclusion that both the equilibrium and pre-equilibrium components of the neutron emission are present in each reaction. However, yields and angular distributions of the pre-equilibrium neutrons emitted in these reactions are considerably different. By comparing the present results with other data, it is shown that the pre-equilibrium neutron emission has a more isotropic distribution than that for protons for the same entrance channel of the reaction. Besides, an information has been obtained on a dependence of the preequilibrium neutron and proton yields on the projectile mass. The data are analysed in terms of a statistical model describing the emission of evaporated neutrons, as well as in terms of the ''rotating hot spot'' model and the moving source model, for preequilibrium neutrons

Polinização de morangueiro por Apis mellifera em ambiente protegido Strawberry polinization through Apis mellifera in protected environment

Directory of Open Access Journals (Sweden)

Eunice Oliveira Calvete

2010-03-01

Full Text Available Este trabalho objetivou comparar a produtividade e a qualidade dos frutos comerciáveis no morangueiro, em ambiente protegido, utilizando a espécie de abelha Apis mellifera em relação à ausência de um agente polinizador. Foram instalados dois experimentos, utilizando-se das cultivares Camarosa, Oso Grande, Diamante e Aromas (tratamentos, no período de 05 de maio a 19 de dezembro de 2006. No primeiro experimento, não havia polinizadores (testemunha. O segundo foi polinizado pela espécie de abelha Apis mellifera. Os tratamentos (cultivares foram dispostos, em cada experimento, em um delineamento completamente casualizado, com seis repetições. Foram avaliadas características de rendimento, bem como análise físico-química dos frutos de cada cultivar. Quanto ao rendimento, a maior produção obtida foi com a cultivar Camarosa tanto na ausência quanto na presença de polinizadores (907,46 g. planta-1 e 1.054,93 g. planta-1, respectivamente, ao passo que a cultivar Oso Grande apresentou menor número de frutos deformados.This work objectified to compare the productivity and the quality of the strawberry marketable fruits in protected environment, using the species of bee Apis mellifera in relation of the absence of a polinizator agent. It was installed two experiments using the cultivates Camarosa, Oso Grande, Diamante and Aromas (treatments, in the period of May 5 th until December 19th of 2006. The first experiment did not have polinizatores agents (control. The second was polinizated by the species of bee Apis mellifera. The treatments (cultivars had been arranged, in each experiment in a randomized blocks with 6 repetitions. They were evaluated income characteristics, as well as analysis physicist-chemistry of the fruits of each cultivar. For the income, the biggest production was gotten in cultivar Camarosa, for the first and the second experiment (907,46 g. plant-1 and 1054,93 g. plant-1, respectively, in the way that the cultivate

Fissuração pelo Hidrogênio em um Aço API 5L X70 Soldado com Eletrodos Celulósicos de Diferentes Níveis de Resistência

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Camila Goes Mattioli

Full Text Available Resumo Aços classificados segundo a norma do American Petroleum Institute (API enfrentam o problema de trincamento a frio decorrente da soldagem. Neste trabalho foi estudado, por meio do ensaio de implante, o efeito da resistência mecânica do metal de solda sobre a susceptibilidade de um aço API-5L-X70 ao trincamento pelo hidrogênio. As soldas foram realizadas com dispositivo de soldagem por gravidade, usando-se dois eletrodos celulósicos, AWS-E6010 e AWS-E8010. O hidrogênio difusível dos eletrodos foi determinado por cromatografia gasosa. Como resultado do ensaio de implante, observou-se uma tendência maior à fissuração quando foi utilizado o eletrodo AWS-E6010. Isso pode ser relacionado à menor resistência mecânica apresentada pela solda resultante do mesmo e ao fato de o eletrodo ser menos ligado. Assim, o metal de solda pode ter se transformado a temperaturas mais elevadas, o que levou a uma maior migração do hidrogênio para a ZTA. Observou-se, ainda, que mesmo as soldas que não falharam no ensaio apresentaram trincas. Isso pode ser devido às condições de resfriamento do cordão que levaram ao aparecimento ilhas com estruturas frágeis e susceptíveis ao trincamento. Para as menores cargas usadas (0,8.σe, contudo, estas trincas não atingiram um tamanho crítico para a ruptura final do pino sendo ensaiado.

Fertility and reproductive rate of Varroa mite, Varroa destructor, in native and exotic honeybee, Apis mellifera L., colonies under Saudi Arabia conditions

Directory of Open Access Journals (Sweden)

Yehya Alattal

2017-07-01

Full Text Available Varroa mite is the most destructive pest to bee colonies worldwide. In Saudi Arabia, preliminary data indicated high infestation levels in the exotic honeybee colonies; such as Apis mellifera carnica and Apis mellifera ligustica, compared to native honeybee subspecies Apis mellifera jemenitica, which may imply higher tolerance to Varroasis. In this study, fertility and reproductive rate of Varroa mite, Varroa destructor, in capped brood cells of the native honeybee subspecies were investigated and compared with an exotic honeybee subspecies, A. m. carnica. Mite fertility was almost alike (87.5% and 89.4% in the native and craniolan colonies respectively. Similarly, results did not show significant differences in reproduction rate between both subspecies (F = 0.66, Pr > F = 0.42. Number of adult Varroa daughters per fertile mother mite was 2.0 and 2.1 for native and craniolan honeybee subspecies respectively. This may indicate that mechanisms of keeping low infestation rates in the native honeybee colonies are not associated with Varroa reproduction. Therefore, potential factors of keeping lower Varroa infestation rates in native honey bee subspecies should be further investigated.

Antimicrobial activity of plant extracts against the honeybee pathogens, Paenibacillus larvae and Ascosphaera apis and their topical toxicity to Apis mellifera adults.

Science.gov (United States)

Chaimanee, V; Thongtue, U; Sornmai, N; Songsri, S; Pettis, J S

2017-11-01

To explore alternative nonchemical control measures against two honeybee pathogens, Paenibacillus larvae and Ascosphaera apis, 37 plant species were screened for antimicrobial activity. The activity of selected plant extracts was screened using an in vitro disc diffusion assay and the minimal inhibitory concentration (MIC) was determined by the broth microdilution method. The results showed that 36 plant extracts had some antibacterial activity on P. larvae by disc diffusion assay. Chromolaena odorata showed the greatest antibacterial activity against P. larvae (MIC 16-64 μg ml -1 ). Of the 37 tested plants, only seven species, Amomum krervanh, Allium sativum, Cinnamomum sp., Piper betle, Piper ribesioides, Piper sarmentosum and Syzygium aromaticum had inhibitory effects on A. apis (MICs of 32-64 μg ml -1 ). The results demonstrated that promising plant extracts were not toxic to adult bees at the concentrations used in this study. The results demonstrate the potential antimicrobial activity of natural products against honeybee diseases caused by P. larvae and A. apis. Chromolaena odorata in particular showed high bioactivity against P. larvae. Further study is recommended to develop these nonchemical treatments against American foulbrood and chalkbrood in honeybees. This work proposes new natural products for the control of American foulbrood and chalkbrood in honeybees. © 2017 The Society for Applied Microbiology.

Determination of Bortezomib in API Samples Using HPLC: Assessment of Enantiomeric and Diastereomeric Impurities.

Science.gov (United States)

Kamalzadeh, Zahra; Babanezhad, Esmaeil; Ghaffari, Solmaz; Mohseni Ezhiyeh, Alireza; Mohammadnejad, Mahdieh; Naghibfar, Mehdi; Bararjanian, Morteza; Attar, Hossein

2017-08-01

A new, normal phase high performance liquid chromatography (NP-HPLC) method was developed for separation of Bortezomib (BZB) enantiomers and quantitative determination of (1S,2R)-enantiomer of BZB in active pharmaceutical ingredient (API) samples. The developed method was validated based on International Conference on Harmonisation (ICH) guidelines and it was proved to be accurate, precise and robust. The obtained resolution (RS) between the enantiomers was more than 2. The calibration curve for (1S,2R)-enantiomer was found to be linear in the concentration range of 0.24-5.36 mg/L with regression coefficient (R2) of 0.9998. Additionally, the limit of detection (LOD) and limit of quantification (LOQ) were 0.052 and 0.16 mg/L, respectively. Also, in this study, a precise, sensitive and robust gradient reversed-phase HPLC (RP-HPLC) method was developed and validated for determination of BZB in API samples. The detector response was linear over the concentration range of 0.26-1110.5 mg/L. The values of R2, LOD and LOQ were 0.9999, 0.084 and 0.25 mg/L, respectively. For both NP-HPLC and RP-HPLC methods, all of the RSD (%) values obtained in the precision study were 2,000 and RS > 2.0. The performance of two common integration methods of valley to valley and drop perpendicular for drawing the baseline between two adjacent peaks were investigated for the determination of diastereomeric impurity (Imp-D) in the BZB-API samples. The results showed that the valley to valley method outperform the drop perpendicular method for calculation of Imp-D peak areas. Therefore, valley to valley method was chosen for peak integration. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Erosion Behaviour of API X100 Pipeline Steel at Various Impact Angles and Particle Speeds

Directory of Open Access Journals (Sweden)

Paul C. Okonkwo

2016-09-01

Full Text Available Erosion is the gradual removal of material due to solid particle impingement and results in a failure of pipeline materials. In this study, a series of erosion tests were carried out to investigate the influence of particle speed and impact angle on the erosion mechanism of API X100 pipeline steel. A dry erosion machine was used as the test equipment, while the particle speed ranged from 20 to 80 m/s and impact angles of 30° and 90° were used as test parameters. The eroded API X100 steel surface was characterized using scanning electron microscope (SEM and X-ray photoelectron spectroscopy (XPS. The weight loss and erosion rate were also investigated. The results showed that at a 90° impact angle, a ploughing mechanism was occurring on the tested specimens, while material removal through low-angle cutting was the dominant mechanism at lower impact angles. Embedment of alumina particles on the target steel surface, micro-cutting, and low-angle cutting were observed at low impact angles. Therefore, the scratches, cuttings, and severe ploughings observed on some failed oil and gas pipelines could be attributed to the erosion mechanism.

Comparison of the performance and security of free and open source smart card offcard APIs

CSIR Research Space (South Africa)

Chifura, A

2008-09-01

Full Text Available . Off card APIs provide a framework for this by providing interfaces that can be implemented to enhance the communication. This study looks at the performance and security comparisons of several free and open source smart card offcard APIs...

Proton capture in the nuclei 21Ne and 22Ne and its influence on the solar hydrogen burning in the neon-sodium cyclus

International Nuclear Information System (INIS)

Goerres, J.

1983-01-01

The aim of this thesis was to remove the uncertainties in the reaction rates of 21 Ne(p,γ) 22 Na and 22 Ne(p,γ) 23 Na in order to can make founded statements about the hydrogen burning in the NeNa cyclus. After the description of the experimental arrangement the search for resonances in the reaction 21 Ne(p,γ) 22 Na below Esub(p)=355 keV is reported. While the theory of the direct radiation capture is discussed the experimental results of the search for this transitions in 21 Ne(p,γ) 22 Na respectively 22 Ne(p,γ) 23 Na are presented. The astrophysical aspects of the results of this thesis are discussed and summarizingly presented. (orig./HSI) [de

Building RESTful web services with Go learn how to build powerful RESTful APIs with Golang that scale gracefully

CERN Document Server

Yellavula, Naren

2017-01-01

REST is an architectural style that tackles the challenges of building scalable web services and in today's connected world, APIs have taken a central role on the web. APIs provide the fabric through which systems interact, and REST has become synonymous with APIs. The depth, breadth, and ease of use of Go, makes it a breeze for developers to ...

Api m 10, a genuine A. mellifera venom allergen, is clinically relevant but underrepresented in therapeutic extracts.

Science.gov (United States)

Blank, S; Seismann, H; Michel, Y; McIntyre, M; Cifuentes, L; Braren, I; Grunwald, T; Darsow, U; Ring, J; Bredehorst, R; Ollert, M; Spillner, E

2011-10-01

Generalized systemic reactions to stinging hymenoptera venom constitute a potentially fatal condition in venom-allergic individuals. Hence, the identification and characterization of all allergens is imperative for improvement of diagnosis and design of effective immunotherapeutic approaches. Our aim was the immunochemical characterization of the carbohydrate-rich protein Api m 10, an Apis mellifera venom component and putative allergen, with focus on the relevance of glycosylation. Furthermore, the presence of Api m 10 in honeybee venom (HBV) and licensed venom immunotherapy preparations was addressed. Api m 10 was produced as soluble, aglycosylated protein in Escherichia coli and as differentially glycosylated protein providing a varying degree of fucosylation in insect cells. IgE reactivity and basophil activation of allergic patients were analyzed. For detection of Api m 10 in different venom preparations, a monoclonal human IgE antibody was generated. Both, the aglycosylated and the glycosylated variant of Api m 10 devoid of cross-reactive carbohydrate determinants (CCD), exhibited IgE reactivity with approximately 50% of HBV-sensitized patients. A corresponding reactivity could be documented for the activation of basophils. Although the detection of the native protein in crude HBV suggested content comparable to other relevant allergens, three therapeutical HBV extracts lacked detectable amounts of this component. Api m 10 is a genuine allergen of A. mellifera venom with IgE sensitizing potential in a significant fraction of allergic patients independent of CCD reactivity. Thus, Api m 10 could become a key element for component-resolved diagnostic tests and improved immunotherapeutic approaches in hymenoptera venom allergy. © 2011 John Wiley & Sons A/S.

"Ne opravilsja jeshtsho posle grippa..." : [luuletused] / Aleksei Koroljov

Index Scriptorium Estoniae

Koroljov, Aleksei

2001-01-01

Autor endast lk. 44. Sisu: "Ne opravilsja jeshtsho posle grippa..." ; "Tak plohho mne, kak ne bõlo davno..." ; "Vokrug tebja, kak satellit..." ; "Hotja i ne ossobenno ona..." ; Iz dnevnika ; Zdravõi smõsl ; "V ushko igolnoje prodenu..." ; "Zhenshtshine prostitelnõ nedostatki..." ; "Balagurja, taratorja..." "Kogda bõ sprava - rai..." ; 23-i skorõi ; "Velmozhi v rogozhe iz blazhi i drozhi..."

Beta-delayed proton emission from {sup 20}Mg

Energy Technology Data Exchange (ETDEWEB)

Lund, M.V.; Fynbo, H.O.U.; Howard, A.M.; Kirsebom, O.S.; Munch, M.; Riisager, K. [Aarhus University, Department of Physics and Astronomy, Aarhus C (Denmark); Andreyev, A.; Wadsworth, R. [University of York, Department of Physics, York (United Kingdom); Borge, M.J.G. [CSIC, Instituto de Estructura de la Materia, Madrid (Spain); CERN, ISOLDE, PH Department, Geneva 23 (Switzerland); Cederkaell, J. [Lund University, Department of Nuclear Physics, Lund (Sweden); Witte, H. de; Huyse, M.; Duppen, P. van [Instituut voor Kern- en Stralingsfysica, KU-Leuven, Leuven (Belgium); Fraile, L.M.; Vedia, V. [Universidad Complutense de Madrid, CEI Moncloa, Facultad de Ciencias Fisicas, Madrid (Spain); Greenlees, P.T.; Konki, J.; Rahkila, P. [University of Helsinki, Helsinki Institute of Physics, Helsinki (Finland); University of Jyvaeskylae, Department of Physics, Jyvaeskylae (Finland); Harkness-Brennan, L.J.; Judson, D.S.; Page, R.D. [University of Liverpool, Department of Physics, Oliver Lodge Laboratory, Liverpool (United Kingdom); Jonson, B.; Lindberg, S.; Nilsson, T. [Chalmers University of Technology, Department of Physics, Goeteborg (Sweden); Kurcewicz, J.; Madurga, M.; Rapisarda, E. [CERN, ISOLDE, PH Department, Geneva (Switzerland); Lazarus, I.; Pucknell, V. [STFC Daresbury, Daresbury, Warrington (United Kingdom); Lica, R. [CERN, ISOLDE, PH Department, Geneva (Switzerland); ' ' Horia Hulubei' ' National Institute of Physics and Nuclear Engineering, Magurele (Romania); Marginean, N.; Marginean, R.; Mihai, C.; Negret, A.; Pascu, S.; Rotaru, F.; Stanoiu, M.; Turturica, A. [' ' Horia Hulubei' ' National Institute of Physics and Nuclear Engineering, Magurele (Romania); Marroquin, I.; Nacher, E.; Perea, A.; Tengblad, O. [CSIC, Instituto de Estructura de la Materia, Madrid (Spain); Sotty, C. [Instituut voor Kern- en Stralingsfysica, KU-Leuven, Leuven (Belgium); ' ' Horia Hulubei' ' National Institute of Physics and Nuclear Engineering, Magurele (Romania); Warr, N. [Universitaet Koeln, Institut fuer Kernphysik, Koeln (Germany); Collaboration: IDS Collaboration

2016-10-15

Beta-delayed proton emission from {sup 20} Mg has been measured at ISOLDE, CERN, with the ISOLDE Decay Station (IDS) setup including both charged-particle and gamma-ray detection capabilities. A total of 27 delayed proton branches were measured including seven so far unobserved. An updated decay scheme, including three new resonances above the proton separation energy in {sup 20}Na and more precise resonance energies, is presented. Beta-decay feeding to two resonances above the Isobaric Analogue State (IAS) in {sup 20}Na is observed. This may allow studies of the 4032.9(2.4) keV resonance in {sup 19}Ne through the beta decay of {sup 20}Mg, which is important for the astrophysically relevant reaction {sup 15}O(α, γ){sup 19}Ne. Beta-delayed protons were used to obtain a more precise value for the half-life of {sup 20}Mg, 91.4(1.0) ms. (orig.)

Standard methods for Apis mellifera propolis research

Science.gov (United States)

Propolis is one of the most fascinating honey bee (Apis mellifera L.) products. It is a plant derived product that bees produce from resins that they collect from different plant organs and with which they mix beeswax. Propolis is a building material and a protective agent in the beehive. It also pl...

Gas chromatography coupled to atmospheric pressure ionization mass spectrometry (GC-API-MS): Review

International Nuclear Information System (INIS)

Li, Du-Xin; Gan, Lin; Bronja, Amela; Schmitz, Oliver J.

2015-01-01

Although the coupling of GC/MS with atmospheric pressure ionization (API) has been reported in 1970s, the interest in coupling GC with atmospheric pressure ion source was expanded in the last decade. The demand of a “soft” ion source for preserving highly diagnostic molecular ion is desirable, as compared to the “hard” ionization technique such as electron ionization (EI) in traditional GC/MS, which fragments the molecule in an extensive way. These API sources include atmospheric pressure chemical ionization (APCI), atmospheric pressure photoionization (APPI), atmospheric pressure laser ionization (APLI), electrospray ionization (ESI) and low temperature plasma (LTP). This review discusses the advantages and drawbacks of this analytical platform. After an introduction in atmospheric pressure ionization the review gives an overview about the history and explains the mechanisms of various atmospheric pressure ionization techniques used in combination with GC such as APCI, APPI, APLI, ESI and LTP. Also new developments made in ion source geometry, ion source miniaturization and multipurpose ion source constructions are discussed and a comparison between GC-FID, GC-EI-MS and GC-API-MS shows the advantages and drawbacks of these techniques. The review ends with an overview of applications realized with GC-API-MS. - Highlights: • Atmospheric pressure ion sources (APCI, ESI, APPI, APLC etc) enable the coupling of LC-based high-end MS to GC. • APIs show advantages in selectivity and sensitivity compared with EI in GC-MS. • Accurate mass database in GC-APCI/MS is emerging as an alternative to GC-EI/MS database.

Gas chromatography coupled to atmospheric pressure ionization mass spectrometry (GC-API-MS): Review

Energy Technology Data Exchange (ETDEWEB)

Li, Du-Xin; Gan, Lin; Bronja, Amela [University of Duisburg-Essen, Applied Analytical Chemistry, Universitaetsstr. 5-7, 45141 Essen (Germany); Schmitz, Oliver J., E-mail: oliver.schmitz@uni-due.de [University of Duisburg-Essen, Applied Analytical Chemistry, Universitaetsstr. 5-7, 45141 Essen (Germany)

2015-09-03

Although the coupling of GC/MS with atmospheric pressure ionization (API) has been reported in 1970s, the interest in coupling GC with atmospheric pressure ion source was expanded in the last decade. The demand of a “soft” ion source for preserving highly diagnostic molecular ion is desirable, as compared to the “hard” ionization technique such as electron ionization (EI) in traditional GC/MS, which fragments the molecule in an extensive way. These API sources include atmospheric pressure chemical ionization (APCI), atmospheric pressure photoionization (APPI), atmospheric pressure laser ionization (APLI), electrospray ionization (ESI) and low temperature plasma (LTP). This review discusses the advantages and drawbacks of this analytical platform. After an introduction in atmospheric pressure ionization the review gives an overview about the history and explains the mechanisms of various atmospheric pressure ionization techniques used in combination with GC such as APCI, APPI, APLI, ESI and LTP. Also new developments made in ion source geometry, ion source miniaturization and multipurpose ion source constructions are discussed and a comparison between GC-FID, GC-EI-MS and GC-API-MS shows the advantages and drawbacks of these techniques. The review ends with an overview of applications realized with GC-API-MS. - Highlights: • Atmospheric pressure ion sources (APCI, ESI, APPI, APLC etc) enable the coupling of LC-based high-end MS to GC. • APIs show advantages in selectivity and sensitivity compared with EI in GC-MS. • Accurate mass database in GC-APCI/MS is emerging as an alternative to GC-EI/MS database.

Determinants of quality, latency, and amount of Stack Overflow answers about recent Android APIs.

Science.gov (United States)

Kavaler, David; Filkov, Vladimir

2018-01-01

Stack Overflow is a popular crowdsourced question and answer website for programming-related issues. It is an invaluable resource for software developers; on average, questions posted there get answered in minutes to an hour. Questions about well established topics, e.g., the coercion operator in C++, or the difference between canonical and class names in Java, get asked often in one form or another, and answered very quickly. On the other hand, questions on previously unseen or niche topics take a while to get a good answer. This is particularly the case with questions about current updates to or the introduction of new application programming interfaces (APIs). In a hyper-competitive online market, getting good answers to current programming questions sooner could increase the chances of an app getting released and used. So, can developers anyhow, e.g., hasten the speed to good answers to questions about new APIs? Here, we empirically study Stack Overflow questions pertaining to new Android APIs and their associated answers. We contrast the interest in these questions, their answer quality, and timeliness of their answers to questions about old APIs. We find that Stack Overflow answerers in general prioritize with respect to currentness: questions about new APIs do get more answers, but good quality answers take longer. We also find that incentives in terms of question bounties, if used appropriately, can significantly shorten the time and increase answer quality. Interestingly, no operationalization of bounty amount shows significance in our models. In practice, our findings confirm the value of bounties in enhancing expert participation. In addition, they show that the Stack Overflow style of crowdsourcing, for all its glory in providing answers about established programming knowledge, is less effective with new API questions.

Transcriptome analysis of the honey bee fungal pathogen, Ascosphaera apis: implications for host pathogenesis

Directory of Open Access Journals (Sweden)

Cornman R

2012-06-01

Full Text Available Abstract Background We present a comprehensive transcriptome analysis of the fungus Ascosphaera apis, an economically important pathogen of the Western honey bee (Apis mellifera that causes chalkbrood disease. Our goals were to further annotate the A. apis reference genome and to identify genes that are candidates for being differentially expressed during host infection versus axenic culture. Results We compared A. apis transcriptome sequence from mycelia grown on liquid or solid media with that dissected from host-infected tissue. 454 pyrosequencing provided 252 Mb of filtered sequence reads from both culture types that were assembled into 10,087 contigs. Transcript contigs, protein sequences from multiple fungal species, and ab initio gene predictions were included as evidence sources in the Maker gene prediction pipeline, resulting in 6,992 consensus gene models. A phylogeny based on 12 of these protein-coding loci further supported the taxonomic placement of Ascosphaera as sister to the core Onygenales. Several common protein domains were less abundant in A. apis compared with related ascomycete genomes, particularly cytochrome p450 and protein kinase domains. A novel gene family was identified that has expanded in some ascomycete lineages, but not others. We manually annotated genes with homologs in other fungal genomes that have known relevance to fungal virulence and life history. Functional categories of interest included genes involved in mating-type specification, intracellular signal transduction, and stress response. Computational and manual annotations have been made publicly available on the Bee Pests and Pathogens website. Conclusions This comprehensive transcriptome analysis substantially enhances our understanding of the A. apis genome and its expression during infection of honey bee larvae. It also provides resources for future molecular studies of chalkbrood disease and ultimately improved disease management.

Transcriptome analysis of the honey bee fungal pathogen, Ascosphaera apis: implications for host pathogenesis

Science.gov (United States)

2012-01-01

Background We present a comprehensive transcriptome analysis of the fungus Ascosphaera apis, an economically important pathogen of the Western honey bee (Apis mellifera) that causes chalkbrood disease. Our goals were to further annotate the A. apis reference genome and to identify genes that are candidates for being differentially expressed during host infection versus axenic culture. Results We compared A. apis transcriptome sequence from mycelia grown on liquid or solid media with that dissected from host-infected tissue. 454 pyrosequencing provided 252 Mb of filtered sequence reads from both culture types that were assembled into 10,087 contigs. Transcript contigs, protein sequences from multiple fungal species, and ab initio gene predictions were included as evidence sources in the Maker gene prediction pipeline, resulting in 6,992 consensus gene models. A phylogeny based on 12 of these protein-coding loci further supported the taxonomic placement of Ascosphaera as sister to the core Onygenales. Several common protein domains were less abundant in A. apis compared with related ascomycete genomes, particularly cytochrome p450 and protein kinase domains. A novel gene family was identified that has expanded in some ascomycete lineages, but not others. We manually annotated genes with homologs in other fungal genomes that have known relevance to fungal virulence and life history. Functional categories of interest included genes involved in mating-type specification, intracellular signal transduction, and stress response. Computational and manual annotations have been made publicly available on the Bee Pests and Pathogens website. Conclusions This comprehensive transcriptome analysis substantially enhances our understanding of the A. apis genome and its expression during infection of honey bee larvae. It also provides resources for future molecular studies of chalkbrood disease and ultimately improved disease management. PMID:22747707

Determinants of quality, latency, and amount of Stack Overflow answers about recent Android APIs

Science.gov (United States)

Filkov, Vladimir

2018-01-01

Stack Overflow is a popular crowdsourced question and answer website for programming-related issues. It is an invaluable resource for software developers; on average, questions posted there get answered in minutes to an hour. Questions about well established topics, e.g., the coercion operator in C++, or the difference between canonical and class names in Java, get asked often in one form or another, and answered very quickly. On the other hand, questions on previously unseen or niche topics take a while to get a good answer. This is particularly the case with questions about current updates to or the introduction of new application programming interfaces (APIs). In a hyper-competitive online market, getting good answers to current programming questions sooner could increase the chances of an app getting released and used. So, can developers anyhow, e.g., hasten the speed to good answers to questions about new APIs? Here, we empirically study Stack Overflow questions pertaining to new Android APIs and their associated answers. We contrast the interest in these questions, their answer quality, and timeliness of their answers to questions about old APIs. We find that Stack Overflow answerers in general prioritize with respect to currentness: questions about new APIs do get more answers, but good quality answers take longer. We also find that incentives in terms of question bounties, if used appropriately, can significantly shorten the time and increase answer quality. Interestingly, no operationalization of bounty amount shows significance in our models. In practice, our findings confirm the value of bounties in enhancing expert participation. In addition, they show that the Stack Overflow style of crowdsourcing, for all its glory in providing answers about established programming knowledge, is less effective with new API questions. PMID:29547620

‘Transnationalising’ Ne Bis In Idem: How the Rule of Ne Bis In Idem Reveals the Principle of Personal Legal Certainty

Directory of Open Access Journals (Sweden)

Juliette Lelieur

2013-09-01

Full Text Available Since Article 54 of the Convention implementing the Schengen Agreement gave the rule of ne bis in idem a transnational dimension, talk of the ‘transnational ne bis in idem principle’ has been commonplace. Thus, when looking for general principles of transnational criminal law, scholars refer to the principle of ‘transnational ne bis in idem’. It is doubtful, however, that ne bis in idem qualifies as a principle of law. It should be regarded, rather, as a rule of criminal procedure, traditionally based on the principle of res judicata. Giving the rule of ne bis in idem a transnational dimension therefore requires either transnationalising the principle of res judicata, or giving the rule of ne bis in idem a new foundation.The principle of res judicata principally serves the credibility of the justice system in a given jurisdiction by prohibiting several tribunals, all acting within the parameters of their jurisdiction, from contradicting each other’s interpretation of the same facts. For this reason, the principle of res judicata does not provide an adequate basis for a transnationalised rule of ne bis in idem.From a human rights perspective, multiple prosecutions against the same person for the same facts collides with protecting individuals against arbitrary judicial treatment. This is true whether the multiple prosecutions all take place in one country or in several different countries. The rule of ne bis in idem could therefore be regarded as a manifestation of the (new ‘principle of personal legal certainty’.

One-neutron knockout from {sup 24-28}Ne isotopes

Energy Technology Data Exchange (ETDEWEB)

Rodriguez-Tajes, C., E-mail: carme.rodriguez@usc.e [Departamento de Fisica de Particulas, Universidade de Santiago de Compostela, 15782 Santiago de Compostela (Spain); Cortina-Gil, D.; Alvarez-Pol, H. [Departamento de Fisica de Particulas, Universidade de Santiago de Compostela, 15782 Santiago de Compostela (Spain); Aumann, T. [GSI Helmholtzzentrum fuer Schwerionenforschung, 64291 Darmstadt (Germany); Benjamim, E.; Benlliure, J. [Departamento de Fisica de Particulas, Universidade de Santiago de Compostela, 15782 Santiago de Compostela (Spain); Borge, M.J.G. [Instituto de Estructura de la Materia, CSIC, 28006 Madrid (Spain); Caamano, M.; Casarejos, E. [Departamento de Fisica de Particulas, Universidade de Santiago de Compostela, 15782 Santiago de Compostela (Spain); Chatillon, A. [GSI Helmholtzzentrum fuer Schwerionenforschung, 64291 Darmstadt (Germany); Eppinger, K.; Faestermann, T. [Physik Department E12, Technische Universitaet Muenchen, 85748 Garching (Germany); Gascon, M. [Departamento de Fisica de Particulas, Universidade de Santiago de Compostela, 15782 Santiago de Compostela (Spain); Geissel, H. [GSI Helmholtzzentrum fuer Schwerionenforschung, 64291 Darmstadt (Germany); Gernhaeuser, R. [Physik Department E12, Technische Universitaet Muenchen, 85748 Garching (Germany); Jonson, B. [Fundamental Fysik, Chalmers Tekniska Hoegskola, 412 96 Goeteborg (Sweden); PH Department, CERN, 1211 Geneve 23 (Switzerland); Kanungo, R. [Astronomy and Physics Department, Saint Mary' s University, Halifax, NS B3H 3C3 (Canada); Kruecken, R. [Physik Department E12, Technische Universitaet Muenchen, 85748 Garching (Germany); Kurtukian, T. [Departamento de Fisica de Particulas, Universidade de Santiago de Compostela, 15782 Santiago de Compostela (Spain); Larsson, K. [Fundamental Fysik, Chalmers Tekniska Hoegskola, 412 96 Goeteborg (Sweden)

2010-04-05

One-neutron knockout reactions of {sup 24-28}Ne in a beryllium target have been studied in the Fragment Separator (FRS), at GSI. The results include inclusive one-neutron knockout cross-sections as well as longitudinal-momentum distributions of the knockout fragments. The ground-state structure of the neutron-rich neon isotopes was obtained from an analysis of the measured momentum distributions. The results indicate that the two heaviest isotopes, {sup 27}Ne and {sup 28}Ne, are dominated by a configuration in which a s{sub 1/2} neutron is coupled to an excited state of the {sup 26}Ne and {sup 27}Ne core, respectively.

Validation of methods for WDXRF and OES-spark techniques in steel analysis. Determination of the uncertainty of measurements for API steel plant sample; Validacao de metodos para as tecnicas de WDXRF e OES-spark na analise de acos. Calculo de incerteza de medicao para amostras de processo, aco classe API

Energy Technology Data Exchange (ETDEWEB)

Silva, Carlos Eduardo da

2009-07-01

The increase of gas and petroleum demanding in the national and international markets, the specification and certification of the chemical analysis results of gas and oil pipe-line have became more and more challenging. A continuous development has been outlined to improve API grade alloy steels (American Petroleum Institute). The steel properties depend on the chemical composition control and process parameters during its manufacturing. In this work, a comparison of the measurement uncertainty between X-ray fluorescence (WD system) and Optical Emission (OES-spark) spectrometry, for API grade steel plant samples analysis, was outlined. Usually, this kind of analyze requires less than 40 seconds for full chemical characterization for adjustment in the process parameters production. The main influence source in the chemical analysis was evaluated for design of experiments. The constituents and trace elements such as Al, Si, P, S, Ti, V, Cr, Mn, Co, Ni, Cu, As, Nb, Mo and Sn were determined using the ASTM E-322, E-415, E-1009 and E-1085 standard methodologies. The 185A and 187A certified reference materials from CMI (Czech Metrology Institute) were used for evaluation of the methods. The uncertainty of the measurement, precision, accuracy, repeatability and reproducibility of the measurements were obtained applying statistic tests, recommended by ISO/IEC 17025. The uncertainty of measurement for each element is discussed for both techniques. (author)

An adaptive software defined radio design based on a standard space telecommunication radio system API

Science.gov (United States)

Xiong, Wenhao; Tian, Xin; Chen, Genshe; Pham, Khanh; Blasch, Erik

2017-05-01

Software defined radio (SDR) has become a popular tool for the implementation and testing for communications performance. The advantage of the SDR approach includes: a re-configurable design, adaptive response to changing conditions, efficient development, and highly versatile implementation. In order to understand the benefits of SDR, the space telecommunication radio system (STRS) was proposed by NASA Glenn research center (GRC) along with the standard application program interface (API) structure. Each component of the system uses a well-defined API to communicate with other components. The benefit of standard API is to relax the platform limitation of each component for addition options. For example, the waveform generating process can support a field programmable gate array (FPGA), personal computer (PC), or an embedded system. As long as the API defines the requirements, the generated waveform selection will work with the complete system. In this paper, we demonstrate the design and development of adaptive SDR following the STRS and standard API protocol. We introduce step by step the SDR testbed system including the controlling graphic user interface (GUI), database, GNU radio hardware control, and universal software radio peripheral (USRP) tranceiving front end. In addition, a performance evaluation in shown on the effectiveness of the SDR approach for space telecommunication.

Emission of high-energy charged particles at 00 in Ne-induced reactions

International Nuclear Information System (INIS)

Borcea, C.; Gierlik, E.; Kalinin, A.M.; Kalpakchieva, R.; Oganessia, Yu.Ts.; Pawlat, T.; Penionzhkevich, Yu.E.; Ryakhlyuk, A.V.

1982-01-01

Inclusive energy spectra have been measured for light charged particles emitted in the bombardment of 232 Th, 181 Ta, sup(nat)Ti and 12 C targets by 22 Ne ions at 178 MeV and sup(nat)Ti target by 20 Ne ions at 196 MeV. The reaction products were analysed and detected by means of a ΔE-E telescope placed in the focal plane of a magnetic spectrometer located at an angle of 0 deg with respect to the beam direction. In all the reactions studied light charged particles with an energy close to the respective calculated kinematic limit for a two-body exit channel are produced with relatively great probability. The results obtained make it possible to draw some conclusions about the reaction mechanism involving the emission of light charged particles

Dark Matter Search in a Proton Beam Dump with MiniBooNE.

Science.gov (United States)

Aguilar-Arevalo, A A; Backfish, M; Bashyal, A; Batell, B; Brown, B C; Carr, R; Chatterjee, A; Cooper, R L; deNiverville, P; Dharmapalan, R; Djurcic, Z; Ford, R; Garcia, F G; Garvey, G T; Grange, J; Green, J A; Huelsnitz, W; de Icaza Astiz, I L; Karagiorgi, G; Katori, T; Ketchum, W; Kobilarcik, T; Liu, Q; Louis, W C; Marsh, W; Moore, C D; Mills, G B; Mirabal, J; Nienaber, P; Pavlovic, Z; Perevalov, D; Ray, H; Roe, B P; Shaevitz, M H; Shahsavarani, S; Stancu, I; Tayloe, R; Taylor, C; Thornton, R T; Van de Water, R; Wester, W; White, D H; Yu, J

2017-06-02

The MiniBooNE-DM Collaboration searched for vector-boson mediated production of dark matter using the Fermilab 8-GeV Booster proton beam in a dedicated run with 1.86×10^{20} protons delivered to a steel beam dump. The MiniBooNE detector, 490 m downstream, is sensitive to dark matter via elastic scattering with nucleons in the detector mineral oil. Analysis methods developed for previous MiniBooNE scattering results were employed, and several constraining data sets were simultaneously analyzed to minimize systematic errors from neutrino flux and interaction rates. No excess of events over background was observed, leading to a 90% confidence limit on the dark matter cross section parameter, Y=ε^{2}α_{D}(m_{χ}/m_{V})^{4}≲10^{-8}, for α_{D}=0.5 and for dark matter masses of 0.01dark matter. This is the best limit from a dedicated proton beam dump search in this mass and coupling range and extends below the mass range of direct dark matter searches. These results demonstrate a novel and powerful approach to dark matter searches with beam dump experiments.

Early process development of API applied to poorly water-soluble TBID.

Science.gov (United States)

Meise, Marius; Niggemann, Matthias; Dunens, Alexandra; Schoenitz, Martin; Kuschnerow, Jan C; Kunick, Conrad; Scholl, Stephan

2018-05-01

Finding and optimising of synthesis processes for active pharmaceutical ingredients (API) is time consuming. In the finding phase, established methods for synthesis, purification and formulation are used to achieve a high purity API for biological studies. For promising API candidates, this is followed by pre-clinical and clinical studies requiring sufficient quantities of the active component. Ideally, these should be produced with a process representative for a later production process and suitable for scaling to production capacity. This work presents an overview of different approaches for process synthesis based on an existing lab protocol. This is demonstrated for the production of the model drug 4,5,6,7-tetrabromo-2-(1H-imidazol-2-yl) isoindolin-1,3-dione (TBID). Early batch synthesis and purification procedures typically suffer from low and fluctuating yields and purities due to poor process control. In a first step the literature synthesis and purification procedure was modified and optimized using solubility measurements, targeting easier and safer processing for consecutive studies. Copyright © 2018 Elsevier B.V. All rights reserved.

Challenges associated with the honey bee ( Apis Mellifera Adansonii )

African Journals Online (AJOL)

Challenges associated with the honey bee ( Apis Mellifera Adansonii ) colonies ... Diseases like American and European foulbrood were absent while ... African Journal of Food, Agriculture, Nutrition and Development, Volume 13 No. 2 April ...

Influence of preheating on API 5L-X80 pipeline joint welding with self shielded flux-cored wire; Influencia del precalentamiento en las propiedades de uniones soldadas de acero API 5L-X80 soldadas con alambre tubular autoprotegido

Energy Technology Data Exchange (ETDEWEB)

Cooper, R.; Silva, J. H. F.; Trevisan, R. E.

2004-07-01

The present work refers to the characterization of API 5L-X80 pipeline joints welded with self-shielded flux cored wire. This process was evaluated under preheating conditions, with an uniform and steady heat input. All joints were welded in flat position (1G), with the pipe turning and the torch still. Tube dimensions were 762 mm in external diameter and 16 mm in thickness. Welds were applied on single V-groove, with six weld beads, along with three levels of preheating temperatures (room temperature, 100 degree centigree, 160 degree centigree). These temperatures were maintained as inter pass temperature. The filler metal E71T8-K6 with mechanical properties different from parent metal was used in under matched conditions. The weld characterization is presented according to the mechanical test results of tensile strength, hardness and impact test. The mechanical tests were conducted according to API 1104, AWS and ASTM standards. API 1104 and API 51 were used as screening criteria. According to the results obtained, it was possible to remark that it is appropriate to weld API 5L-X80 steel ducts with Self-shielded Flux Cored wires, in conformance to the API standards and no preheat temperature is necessary. (Author) 22 refs.

Status of the KM3NeT project

International Nuclear Information System (INIS)

Margiotta, A

2014-01-01

KM3NeT is a deep-sea research infrastructure being constructed in the Mediterranean Sea. It will be installed at three sites: KM3NeT-Fr, offshore Toulon, France, KM3NeT-It, offshore Portopalo di Capo Passero, Sicily (Italy) and KM3NeT-Gr, offshore Pylos, Peloponnese, Greece. It will host the next generation Cherenkov neutrino telescope and nodes for a deep sea multidisciplinary observatory, providing oceanographers, marine biologists, and geophysicists with real time measurements. The neutrino telescope will search for Galactic and extra-Galactic sources of neutrinos, complementing IceCube in its field of view. The detector will have a modular structure and consists of six building blocks, each including about one hundred Detection Units (DUs). Each DU will be equipped with 18 multi-PMT digital optical modules. The first phase of construction has started and shore and deep-sea infrastructures hosting the future KM3NeT detector are being prepared in France near Toulon and in Italy, near Capo Passero in Sicily. The technological solutions for KM3NeT and the expected performance of the detector are presented and discussed

Comments on Auger electron production by Ne/sup +/ bombardment of surfaces

Energy Technology Data Exchange (ETDEWEB)

Pepper, S V; Ferrante, J [National Aeronautics and Space Administration, Cleveland, OH (USA). Lewis Research Center

1979-09-01

In this letter, the authors first report rather conclusive experimental evidence showing that the Ne Auger signal is due to asymmetric Ne-metal collisions and not symmetric Ne-Ne collisions. Next it is shown that the Ne Auger signal is in fact observable by Ne/sup +/ bombardment of Si and with signal strength comparable to that of the Si Auger signal for 3 keV incident ion energy. Finally, they comment on some trends in the relative amplitudes of the 21.9 and 25.1 eV Ne Auger signals as a function of incident ion energy and target species.

The biochemical properties of the Arabidopsis ecto-nucleoside triphosphate diphosphohydrolase AtAPY1 contradict a direct role in purinergic signaling.

Directory of Open Access Journals (Sweden)

Carolin Massalski

Full Text Available The Arabidopsis E-NTPDase (ecto-nucleoside triphosphate diphosphohydrolase AtAPY1 was previously shown to be involved in growth and development, pollen germination and stress responses. It was proposed to perform these functions through regulation of extracellular ATP signals. However, a GFP-tagged version was localized exclusively in the Golgi and did not hydrolyze ATP. In this study, AtAPY1 without the bulky GFP-tag was biochemically characterized with regard to its suggested role in purinergic signaling. Both the full-length protein and a soluble form without the transmembrane domain near the N-terminus were produced in HEK293 cells. Of the twelve nucleotide substrates tested, only three--GDP, IDP and UDP--were hydrolyzed, confirming that ATP was not a substrate of AtAPY1. In addition, the effects of pH, divalent metal ions, known E-NTPDase inhibitors and calmodulin on AtAPY1 activity were analyzed. AtAPY1-GFP extracted from transgenic Arabidopsis seedlings was included in the analyses. All three AtAPY1 versions exhibited very similar biochemical properties. Activity was detectable in a broad pH range, and Ca(2+, Mg(2+ and Mn(2+ were the three most efficient cofactors. Of the inhibitors tested, vanadate was the most potent one. Surprisingly, sulfonamide-based inhibitors shown to inhibit other E-NTPDases and presumed to inhibit AtAPY1 as well were not effective. Calmodulin stimulated the activity of the GFP-tagless membranous and soluble AtAPY1 forms about five-fold, but did not alter their substrate specificities. The apparent Km values obtained with AtAPY1-GFP indicate that AtAPY1 is primarily a GDPase. A putative three-dimensional structural model of the ecto-domain is presented, explaining the potent inhibitory potential of vanadate and predicting the binding mode of GDP. The found substrate specificity classifies AtAPY1 as a nucleoside diphosphatase typical of N-terminally anchored Golgi E-NTPDases and negates a direct function in

Ductile failure analysis of defective API X65 pipes based on stress-modified fracture strain criterion

International Nuclear Information System (INIS)

Oh, Chang Kyun; Kim, Yun Jae; Baek, Jong Hyun; Kim, Young Pyo; Kim, Woo Sik

2006-01-01

A local failure criterion for the API X65 steel is applied to predict ductile failure of full-scale API X65 pipes with simulated corrosion and gouge defects under internal pressure. The local failure criterion is the stress-modified fracture strain for the API X65 steel as a function of the stress triaxiality (defined by the ratio of the hydrostatic stress to the effective stress). Based on detailed FE analyses with the proposed local failure criteria, burst pressures of defective pipes are estimated and compared with experimental data. The predicted burst pressures are in good agreement with experimental data. Noting that an assessment equation against the gouge defect is not yet available, parametric study is performed, from which a simple equation is proposed to predict burst pressure for API X65 pipes with gouge defects

Gas chromatography coupled to atmospheric pressure ionization mass spectrometry (GC-API-MS): review.

Science.gov (United States)

Li, Du-Xin; Gan, Lin; Bronja, Amela; Schmitz, Oliver J

2015-09-03

Although the coupling of GC/MS with atmospheric pressure ionization (API) has been reported in 1970s, the interest in coupling GC with atmospheric pressure ion source was expanded in the last decade. The demand of a "soft" ion source for preserving highly diagnostic molecular ion is desirable, as compared to the "hard" ionization technique such as electron ionization (EI) in traditional GC/MS, which fragments the molecule in an extensive way. These API sources include atmospheric pressure chemical ionization (APCI), atmospheric pressure photoionization (APPI), atmospheric pressure laser ionization (APLI), electrospray ionization (ESI) and low temperature plasma (LTP). This review discusses the advantages and drawbacks of this analytical platform. After an introduction in atmospheric pressure ionization the review gives an overview about the history and explains the mechanisms of various atmospheric pressure ionization techniques used in combination with GC such as APCI, APPI, APLI, ESI and LTP. Also new developments made in ion source geometry, ion source miniaturization and multipurpose ion source constructions are discussed and a comparison between GC-FID, GC-EI-MS and GC-API-MS shows the advantages and drawbacks of these techniques. The review ends with an overview of applications realized with GC-API-MS. Copyright © 2015. Published by Elsevier B.V.

Pim-2 activates API-5 to inhibit the apoptosis of hepatocellular carcinoma cells through NF-kappaB pathway.

Science.gov (United States)

Ren, Ke; Zhang, Wei; Shi, Yujun; Gong, Jianping

2010-06-01

Pim-2 is proved to be relevant to the tumorigenesis of hepatocellular carcinoma (HCC), but the mechanism is unclear. We studied the relationship among Pim-2, NF-kappaB and API-5. In our experiment, expression level of the three factors and phosphorylation level of API-5, as well as NF-kappaB activity, were detected in HCC tissues and the nontumorous controls. Then Pim-2 gene was transfected into nontumorous liver cells L02, and Pim-2 SiRNA was transfected into hepatoblastoma cell line HepG2. Parthenolide was added as NF-kappaB inhibitor. The same detections as above were repeated in the cells, along with the apoptosis analysis. We found the levels of Pim-2, NF-kappaB and API-5, as well as NF-kappaB activity, were significantly higher in HCC tissues. Pim-2 level was increased in L02 cells after the transfection of Pim-2 gene, but decreased in HepG2 cells after the transfection of Pim-2 SiRNA. The levels of NF-kappaB and API-5, as well as NF-kappaB activity and API-5 phosphorylation level, were in accordance with Pim-2 level, but could be reversed by Parthenolide. Cell apoptosis rates were negatively correlated with API-5 phosphorylation level. Therefore, we infer that Pim-2 could activate API-5 to inhibit the apoptosis of liver cells, and NF-kappaB is the key regulator.

20º Aniversario Piel para Renacer Fundación del Quemado

Directory of Open Access Journals (Sweden)

L. Guerrero-Serrano