WorldWideScience

Sample records for apa

  1. APA Council Reports.

    Science.gov (United States)

    2017-10-01

    At the fall component meetings of the American Psychiatric Association in Arlington, Va., September 13-16, 2017, the APA councils heard reports from their components. Following are summaries of the activities of the councils and their components.

  2. Demystifying APA style.

    Science.gov (United States)

    Cuddy, Claudia M

    2002-01-01

    Many nursing schools and health care journals have adopted the Publication Manual of the American Psychological Association (APA stylebook) as their guide to achieve uniformity and consistency in manuscript preparation as well as in usage and writing style. Published in 2001, the fifth edition of the APA stylebook contains 440 pages and can overwhelm someone who tries to use it for the first time. This article delineates main points in the areas of manuscript preparation, reference lists, in-text citations, and style choices.

  3. Estilos de referencia APA

    OpenAIRE

    Gomis Selva, Nieves; Delgado Domenech, Beatriz; González García, María; Sánchez Colodrero, Vicente; Jover Mira, Irene; León Antón, María José

    2011-01-01

    El estilo de referencia de la Asociación Psicológica Americana (APA) es el formato más aceptado y comúnmente utilizado por profesionales e investigadores de ciencias sociales, como Psicología, Magisterio, Enfermería, Criminología, Relaciones públicas, entre otras. La adopción de un estilo de referencia compartido facilita la elaboración y redacción de trabajos, así como la comprensión por parte de otros profesionales interesados por disciplinas afines. Por ello, es imprescindible que los futu...

  4. Academic Practice, APA Referencing Style

    DEFF Research Database (Denmark)

    Nielsen, Sandro; Heine, Carmen

    kildeangivelse og referencer i henhold til APA referencing system.Vejledning i at undgå plagiering ved at følge de normer, der gælder for good academic practice. Dette indebærer at man angiver kilder korrekt, og når det er nødvendigt, og at man har en korrekt udformet fortegnelse over referencer. Vejledningen...... indeholder konkrete eksempler på korrekt kildeangivelse og referencer i henhold til APA referencing system....

  5. ADA APA DENGAN KECEMASAN MATEMATIKA?

    OpenAIRE

    Fatrima Santri Syafri

    2017-01-01

    ABSTRAK Kecemasan matematika adalah salah satu faktor yang mempengaruhi prestasi belajar matematika. Faktor tersebut dapat dipengaruhi oleh beberapa hal, baik berkaitan dengan faktor internal maupun faktor eksternal peserta didik. Dalam tulisan ini akan membahas tentang apa itu kecemasan matematika, indikator kecemasan matematika, dampak serta cara mengatasinya. Berdasarkan beberapa penelitian tentang kecemasan matematika, terlihat bahwa kecemasan matematika sangat berpengaruh negatif ter...

  6. Recognition of psychotherapy effectiveness: the APA resolution.

    Science.gov (United States)

    Campbell, Linda F; Norcross, John C; Vasquez, Melba J T; Kaslow, Nadine J

    2013-03-01

    In August 2012, the American Psychological Association (APA) Council of Representatives voted overwhelmingly to adopt as APA policy a Resolution on the Recognition of Psychotherapy Effectiveness. This invited article traces the origins and intentions of that resolution and its protracted journey through the APA governance labyrinth. We summarize the planned dissemination and projected results of the resolution and identify several lessons learned through the entire process.

  7. Comprehending APA Style through Manuscript Analysis.

    Science.gov (United States)

    Smith, Gabie E.; Eggleston, Tami J.

    2001-01-01

    Describes an activity designed to enhance undergraduate student comprehension of the American Psychological Association (APA) manual and style where students examined a poorly written paper for errors in relation to the APA guidelines. Reports the results of a study that tested the effectiveness of the activity. (CMK)

  8. APA's Role in Fostering Good Testing Practices.

    Science.gov (United States)

    Camara, Wayne J.

    Psychological testing has played a major role in the American Psychological Association (APA) because testing and assessment are important aspects of what psychologists do; tests assist psychologists in diagnosis and treatment. From its earliest years, APA has had one or more committees concerned with testing. The present Committee on…

  9. APA References for Psychologists in Schools & Education.

    Science.gov (United States)

    American Psychological Association, Washington, DC.

    Since its inauguration, the American Psychological Association (APA) Center for Psychology in Schools and Education (CPSE) has provided an integrated approach to coordinating education, public interest, scientific, and practice issues in education. This publication provides a compilation of APA books, journals, newsletters, videotapes, audiotapes,…

  10. Guide to APA-Based Models

    Science.gov (United States)

    Robins, Robert E.; Delisi, Donald P.

    2008-01-01

    In Robins and Delisi (2008), a linear decay model, a new IGE model by Sarpkaya (2006), and a series of APA-Based models were scored using data from three airports. This report is a guide to the APA-based models.

  11. Sport and APA: proces of possible diffusion

    Directory of Open Access Journals (Sweden)

    Hana Válková

    2011-03-01

    Full Text Available Relation between Adapted Physical Activity (APA are described in the article. Recent sport professions as so as professions related to sports are formulated. "Coach" profession is defined with more details, the term "sport of persons with disability" is explained, too. On the bases of personal experience the APA domain which every coach can be touched are presented. Events which recent coaches, sports clubs in Czech Republic participated in are added. The basic questions of EUSAPA project are answered: regular sport and APA are blended together. Diffusion of sport and APA can become good platform for inclusion in life span context. Coaches should be informed about basic principles of APA according the level of connection (humanitarian domain - coaches in sports of disabled, the type of sport (relation to general sport and performance level (recreation - top competitive. The topic APA should be included on adequate level in education courses of coaches. The practice in sport activities of people with disability has to be involved.

  12. Aplicaciones Normas APA y sus tendencias

    OpenAIRE

    Ledesma-Ayora, Marco; Muñoz Cajilima, Néstor Xavier

    2016-01-01

    [ES] Este manual fue elaborado en base a las normas APA (American Psychological Association), actualización y el aporte como tendencias, el anhelo es que sea de beneficio para estudiantes, docentes e investigadores que aplican una buena escritura académica. Las normas APA es un conjunto de referencias para la escritura de trabajos, proyectos y publicaciones, proyectando así su validez y confiabilidad, que permiten visibilizar una correcta formalidad en la presentación, pudiendo ser mediado a ...

  13. Resolving a Conflict between APA Learning Goals and APA Ethical Principles

    Science.gov (United States)

    Corty, Eric W.

    2008-01-01

    Although American Psychological Association (APA) Ethical Standards make it clear that instructors cannot require students to disclose personal information in class-related activities, an APA learning goal for undergraduate psychology students is that they reflect on their experiences to develop insight into their behavior and mental processes.…

  14. Guidelines for Nonsexist Language in APA Journals

    Science.gov (United States)

    American Psychological Association

    1978-01-01

    Sexism in journal writing may be classified as problems of evaluation. Endeavors to change language is a difficult task. Few attempts exist to end sexist language. Careful rephrasing can often result in accurate, unbiased communication. The APA Guidelines attempt to develop awareness and competence in using non-sexist language. (Author/MFD)

  15. Women's Participation in Behavioral and APA Journals.

    Science.gov (United States)

    Morris, Edward K.; And Others

    Concern about the professional socialization of women in academic positions has increased markedly in recent years. This study examined women's participation in behavioral journals and journals published by the American Psychological Association (APA) in terms of journal authorship and the composition of journal editorial boards. Behavioral…

  16. The APA Style Converter: a Web-based interface for converting articles to APA style for publication.

    Science.gov (United States)

    Li, Ping; Cunningham, Krystal

    2005-05-01

    The APA Style Converter is a Web-based tool with which authors may prepare their articles in APA style according to the APA Publication Manual (5th ed.). The Converter provides a user-friendly interface that allows authors to copy and paste text and upload figures through the Web, and it automatically converts all texts, references, and figures to a structured article in APA style. The output is saved in PDF or RTF format, ready for either electronic submission or hardcopy printing.

  17. APA, Meet Google: Graduate Students' Approaches to Learning Citation Style

    Science.gov (United States)

    Van Note Chism, Nancy; Weerakoon, Shrinika

    2012-01-01

    Inspired by Perkins' Theories of Difficulty concept, this exploratory study examined the learning patterns of graduate students as they grappled with using the style sheet of the American Psychological Association (APA). The researchers employed task performance analysis of three APA formatting tasks, interviews, and observation during a "think…

  18. Who Cares about APA Policy and Does it Have an Impact? 2006 Annual Report of the APA Policy and Planning Board

    Science.gov (United States)

    American Psychologist, 2007

    2007-01-01

    What constitutes American Psychological Association (APA) policy? How does it affect the everyday and professional lives of APA members? How personally aware are psychologists of APA policies? In this report, the APA explores these questions and provide some intriguing findings on the fate of policies developed through the APA's complicated and…

  19. Psi Chi/APA Edwin B. Newman Graduate Research Award.

    Science.gov (United States)

    2016-11-01

    The Edwin B. Newman Graduate Research Award is sponsored jointly by Psi Chi, the national honor society in psychology, and the APA. The award is presented annually to the psychology graduate student who submits the best research paper that was published or presented at a national, regional, or state psychological association conference during the past calendar year. The Edwin B. Newman Graduate Research Award is given jointly by Psi Chi and APA. Members of the 2016 Edwin B. Newman Award Committee were Shawn Carlton, PhD, Psi Chi representative; Christina Frederick-Recascino, PhD; John Norcross, PhD, APA representative; Karenna Malavanti, PhD, Psi Chi representative; Steven Kohn, PhD, Psi Chi representative; Warren Fass, PhD, Psi Chi representative; Chris Lovelace, PhD, Psi Chi representative; and Cathy Epkins, PhD, APA representative. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  20. Complexing properties of amide oxime of picolinic acid (APA). 1

    International Nuclear Information System (INIS)

    Oginski, M.; Zommer-Urbanska, S.; Joachimiak, J.; Koniarek, B.

    1983-01-01

    As a result of APA labelling with /sup 99m/Tc reduced by SnCl 2 at pH 1.9 about 90% of the /sup 99m/Tc-APA complex was obtained. Experiments in vivo were carried out on 10 Swiss mice with implanted Ehrlich tumor. After 8 days the /sup 99m/Tc-APA complex was administered i.p. The ADF ratio tumor:blood was 2.5. Renoscintigraphy showed that the decline of renal activity in the stage when excretion prevailed (phase III) was slow and of the cumulative nature. Simple synthesis, labelling and low toxity of APA are the factors that advocate further experiments in investigating its usefulness for diagnostics. (author)

  1. Psi Chi/APA Edwin B. Newman Graduate Research Award.

    Science.gov (United States)

    2017-12-01

    The Edwin B. Newman Graduate Research Award is sponsored jointly by Psi Chi, the national honor society in psychology, and the APA. The award is presented annually to the psychology graduate student who submits the best research paper that was published or presented at a national, regional, or state psychological association conference during the past calendar year. The Edwin B. Newman Graduate Research Award was established in 1979. The award was established to recognize young researchers at the beginning of their professional lives and to commemorate both the 50th anniversary of Psi Chi and the 100th anniversary of psychology as a science (dating from the founding of Wundt's laboratory). It was named for Dr. Edwin B. Newman, the first national president of Psi Chi (1929) and one of its founders. He was a prolific researcher and a long-time chair of the Department of Psychology at Harvard University. Newman was a member of APA's Board of Directors, served as recording secretary of the board from 1962 to 1967, and was parliamentarian for the APA Council of Representatives for many years. He served both Psi Chi and APA in a distinguished manner for half a century. The Edwin B. Newman Graduate Research Award is given jointly by Psi Chi and APA. Members of the 2017 Edwin B. Newman Award Committee were Shawn Carlton, PhD, Psi Chi representative; Christina Frederick-Recascino, PhD; John Norcross, PhD, APA representative; Karenna Malavanti, PhD, Psi Chi representative; Steven Kohn, PhD, Psi Chi representative; Warren Fass, PhD, Psi Chi representative; Chris Lovelace, PhD, Psi Chi representative; and Cathy Epkins, PhD, APA representative. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  2. MAKNA BUDAYA LAGU DOLANAN: DHONDHONG APA SALAK, GUNDHUL PACUL

    OpenAIRE

    Arini Hidayah

    2017-01-01

    Lagu dolanan Jawa Tengah, dhondhong apa salak dan gundhul pacul, mempunyai peranan yang penting untuk anak-anak karena di dalam lagu dolanan tersebut terdapat nilai-nilai pendidikan dan simbol-simbol kehidupan yang dapat dijadikan tuntunan untuk anak-anak. Penelitian ini akan menggali makna budaya yang tersembunyi di dalam lagu dolanan Jawa Tengah yakni dhondhong apa salak, gundhul pacul, dan kupu kuwi agar menemukan pemahaman budaya Jawa Tengah yang tersirat dalam lagu dola...

  3. How to Write a Bachelor Thesis in (APA) Style

    OpenAIRE

    Hirnstein, Marco

    2016-01-01

    Bachelor students at the Faculty of Psychology in Bergen are required to write their thesis according to the guidelines of scientific writing by the American Psychological Association (APA). These guidelines provide help with structuring the thesis, describing research methods, reporting findings, referencing, and using a clear scientific writing style. Despite its relevance, teaching the APA guidelines has been considered somewhat boring by both students and teaching staff – largely due to t...

  4. APA efforts in promoting human rights and social justice.

    Science.gov (United States)

    Leong, Frederick T L; Pickren, Wade E; Vasquez, Melba J T

    2017-11-01

    This article reviews the American Psychological Association's (APA) efforts in promoting human rights and social justice. Beginning with a historical review of the conceptualizations of human rights and social justice, the social challenges that have faced the United States over time are discussed in relation to the APA's evolving mission and strategic initiatives enacted through its boards, committees, and directorates. From early efforts on the Board for Social and Ethical Responsibility in Psychology and the Board of Ethnic Minority Affairs to the establishment of the Public Interest Directorate, the APA's efforts to address these human rights and social justice challenges through its task force reports, guidelines, and policies are described. Specifically, issues related to diversity and underrepresentation of minority group members and perspective within the APA, as well as women's issues (prochoice, violence against women, sexualization of young girls, human trafficking) were central to these efforts. These minority groups included racial and ethnic minority groups; immigrants and refugees; lesbian, gay, bisexual, transgendered, and queer individuals; and those with disabilities. Later attention shifted to broader social justice challenges within a public health perspective, such as AIDS, obesity, and violence. Also included is a brief discussion of the Hoffman Report. The article ends with a discussion of future directions for the APA's efforts related to human rights and social justice related to health disparities, violent extremism, social inequality, migration, cultural and racial diversity, and an evidence-based approach to programming. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  5. Mastering the APA Style of Referencing with Ease | Omotosho ...

    African Journals Online (AJOL)

    Students and lecturers in tertiary institutions whose areas of specialization are in Education and the Social and Behavioural Sciences are required to apply the APA style whenever they submit their projects and papers. However, due to the fact that the Publication Manual of the American Psychological Association is very ...

  6. Re-evaluation of characterisation and classification of Apa ( Afzelia ...

    African Journals Online (AJOL)

    As a result of effect of geographical location on timber properties, there is need for constant determination of properties of timber. This paper presents the results of experimental tests carried out on three Apa (Afzelia bipindensis) timber logs grown in Kwara State, south-western periphery of the North Central Zone of Nigeria ...

  7. Teaching APA Style Documentation: Discovery Learning, Scaffolding and Procedural Knowledge

    Science.gov (United States)

    Skeen, Thomas; Zafonte, Maria

    2015-01-01

    Students struggle with learning correct documentation style as found in the Publication Manual of the American Psychological Association and teachers are often at a loss for how to best instruct students in correct usage of APA style. As such, the first part of this paper discusses the current research on teaching documentation styles as well as…

  8. Instructional Strategies to Improve College Students' APA Style Writing

    Science.gov (United States)

    Mandernach, B. Jean; Zafonte, Maria; Taylor, Caroline

    2016-01-01

    The purpose of this study was to identify areas of APA formatting that college instructors view as most problematic in student writing. Using a Likert-style survey, the greatest areas of reported concern were problems with documentation, specifically, citations, references, and quoting; of lesser concern were various style and formatting errors in…

  9. Quality control in preparation of APA microcapsular immune isolation biomembrane

    International Nuclear Information System (INIS)

    Li Xinjian; Xue Yilong; Lu Qingguo; Li Yanling; Gao Yuhong

    2005-01-01

    For optimization of preparation condition, simplification of technique and quality control, we observed partial physical and chemical factors in process of preparation of alginate-polylysine-alginate (APA) microcapsular immune isolation biomembrane. The result showed that granular diameter of the microcapsules was negatively correlated with pulse frequency of static microcapsule generator and positively correlated with speed of driving pump and bore of pinhead. The membrane thickness was remarkably increased with the increase of polylysine density. Prolonging reaction time of shaping membrane didn't change granular diameter of the microcapsules, but influenced membrane thickness. Liquefaction time of sodium citrate had no remarkable effect on granular diameter and membrane thickness. APA microcapsular immuno isolation biomembrane would have better permeability, flexibility, biological compatibility and intensity by optimizing preparation conditions. (authors)

  10. Casos prácticos Normativa APA 6ª ed.

    OpenAIRE

    Guerras-Frías, Miroslava (tr)

    2010-01-01

    A la hora de realizar un trabajo es importante leer otros documentos relacionados para ver el estado de la cuestión, además de apoyarte en sus teorías para darle valor y peso a tu trabajo. Pero todo trabajo que este basado en otros debe de citar y tener sus referencias bibliográficas normalizadas. Para esto hay muchos estilos validos normalizados, el que aquí nos ocupa es sobre el estilo de la American Psychological Association, más conocido como Nomas o Estilo APA de la 6ª edición.

  11. 76 FR 37876 - Hours of Service (HOS) of Drivers; Renewal of American Pyrotechnics Association (APA) Exemption...

    Science.gov (United States)

    2011-06-28

    ...-28043] Hours of Service (HOS) of Drivers; Renewal of American Pyrotechnics Association (APA) Exemption... announces the renewal of the exemption of specified members of the American Pyrotechnics Association (APA... of this exemption in effect, designated APA-member motor carriers will maintain a level of safety...

  12. 77 FR 38378 - Hours of Service (HOS) of Drivers; Revision of Exemption; American Pyrotechnics Association (APA)

    Science.gov (United States)

    2012-06-27

    ...-28043] Hours of Service (HOS) of Drivers; Revision of Exemption; American Pyrotechnics Association (APA... Pyrotechnics Association (APA) that were granted an exemption from FMCSA's prohibition on driving commercial...-July 8, inclusive, in 2011 and 2012. The exemption covered renewal of 53 APA-member motor carriers and...

  13. 76 FR 37880 - Hours of Service (HOS) of Drivers; Granting of Exemption; American Pyrotechnics Association (APA)

    Science.gov (United States)

    2011-06-28

    ...-28043] Hours of Service (HOS) of Drivers; Granting of Exemption; American Pyrotechnics Association (APA... exemption from the American Pyrotechnics Association (APA) on behalf of 9 member motor carriers seeking... such exemption'' (49 U.S.C. 31315(b)(1)). The initial APA application for waiver or exemption relief...

  14. 76 FR 30232 - Hours of Service (HOS) of Drivers; Application of American Pyrotechnics Association (APA) for...

    Science.gov (United States)

    2011-05-24

    ...-28043] Hours of Service (HOS) of Drivers; Application of American Pyrotechnics Association (APA) for... American Pyrotechnics Association (APA) has applied for a limited exemption from FMCSA's regulation that... exemption would apply solely to the operation of CMVs by 9 designated APA-member motor carriers in...

  15. The APR1400 Core Design by Using APA Code System

    International Nuclear Information System (INIS)

    Choi, Yu Sun; Koh, Byung Marn

    2008-01-01

    The nuclear design for APR1400 has been performed to prepare the core model for Automatic Load Follow Operation Simulation. APA (ALPHA/ PHOENIXP/ ANC) code system is a tool for the multi-cycle depletion calculations for APR1400. Its detail versions for ALPHA, PHOENIX-P and ANC are 8.9.3, 8.6.1 and 8.10.5, respectively. The first and equilibrium core depletion calculations for APR1400 have been performed to assure the target cycle length and confirm the safety parameters. The parameters are satisfied within limitation about nuclear design criteria. This APR1400 core models will be based on the design parameters for APR1400 Simulator

  16. [Language is not neutral. Commentary about APA style].

    Science.gov (United States)

    Delgado Sánchez-Mateos, Juan

    2007-05-01

    Some basic characteristics, not always explicit, of the editorial style proposed by the American Psychological Association (APA), and from the objections posed by some authors who maintain critical positions towards the use of this style, are reviewed, starting with the work of Madigan, Johnson, and Linton (1995) and the subsequent controversy. Starting with this review, problems related to underlying assumptions of the style, with ethical aspects of research, and with the epistemological positions defended by the different traditions of research are discussed. In the conclusions, a simpler differentiation between the scientific-technical and communicative-practical systems of enquiry is proposed, and an explicit commitment, in the text of the report, to the ethical responsibilities derived from the authorship and the development of the research.

  17. Decission Support System (DSS dalam Auditing Untuk Apa Digunakan

    Directory of Open Access Journals (Sweden)

    Priyono Puji Prasetyo

    2015-12-01

    Full Text Available Komputer semakin sering digunakan pada kantor akuntan. Tidak hanya digunakan untuk menggantikan kegiatan yang bersifat manual, tetapi juga sebagai alat bantu bagi akuntan dalam pengambilan keputusan. Keputusan yang dibuat dengan dukungan (decision support sistem komputer ini diharapkan tidak hanya akan lebih efisien, tetapi juga lebih efektif dalam mencapai tujuan. Konsekuensi-nya, bantuan semacam itu memperoleh dukungan yang luas untuk digunakan dalam auditing dan bidang pekerjaan lainnya. Apa yang menyebabkan Decision Support System (DSS digunakan adalah kemampuannya membantu akuntan dalam proses pembuatan keputusan audit. Alat ini perlu dipergunakan oleh akuntan karena profesi akuntansi berhadapan dengan pasar yang semakin besar, saingan yang lebih ketat serta tekanan hukum, sehingga auditor independen dituntut untuk mengembangkan kualitas pelayanan audit dengan harga yang lebih kompetitif.Tulisan ini bertujuan untuk membahas penggunaan Decision Support System (DSS dalam auditing. Pembahasan akan dimulai dengan sejarah perkembangan komputer yang kemudian disusul dengan uraian tentang decision support system (DSS. Uraian yang agak luas mengenai penggunaan DSS dalam auditing diberikan pada seksi berikutnya. Berdasarkan uraian mengenai DSS tersebut akan diberikan kesimpulan untuk mengakhiri tulisan ini.

  18. From print to digital (1985-2015): APA's evolving role in psychological publishing.

    Science.gov (United States)

    VandenBos, Gary R

    2017-11-01

    Knowledge dissemination plays an important role in all scientific fields. The American Psychological Association's (APA) journal publication program was established in 1927. During the 1960s, the Psychological Abstracts publication was computerized. In the mid-1980s, a reenergizing of APA Publishing began, with the establishment of the APA Books Program, as well as the movement of abstracts to CD-ROMs. This article describes the 30-year program of expansion of APA Publishing, covering the period from 1985 through 2015. This period saw the journals program grow from 15 journals to 89 journals, the abstract program grow into an Internet-based delivery system, the creation of the APA's own PsycNET delivery platform, the creation of 6 addition databases, and the establishment of dictionaries and handbooks of psychology. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  19. Guide för referenshantering : APA-manual inom Barn- och ungdomsvetenskap (BUVA)

    OpenAIRE

    Engdahl, Ingrid

    2014-01-01

    Denna guide behandlar först hur du enligt APA refererar i löpande text och därefter hur man skriver en referenslista. För en komplett guide till APA Style hänvisas till Publication Manual of the American Psychological Association (American Psychological Association, 2010) eller till hemsidan http://www.apastyle.org, där det finns tydlig introduktion i ljud och bild till APA Style.

  20. Information Technology & Applications Corporation v. United States: An Interested Party's "Substantial Chance" at APA Standing

    National Research Council Canada - National Science Library

    Slicker, Christina

    2003-01-01

    .... Building on CICA's "interested party" definition with Information Technology's refinement of "substantial chance" rule, the Federal Circuit has effectively translated "APA standing" into the language...

  1. Apa is a trimeric autotransporter adhesin of Actinobacillus pleuropneumoniae responsible for autoagglutination and host cell adherence.

    Science.gov (United States)

    Xiao, Longwen; Zhou, Liang; Sun, Changjiang; Feng, Xin; Du, ChongTao; Gao, Yu; Ji, Qun; Yang, Shuxin; Wang, Yu; Han, Wenyu; Langford, P R; Lei, Liancheng

    2012-10-01

    Actinobacillus pleuropneumoniae is the causative agent of porcine pleuropneumonia, and adherence to host cells is a key step in the pathogenic process. Although trimeric autotransporter adhesins (TAAs) were identified in many pathogenic bacteria in recent years, none in A. pleuropneumoniae have been characterized. In this study, we identified a TAA from A. pleuropneumoniae, Apa, and characterized the contribution of its amino acid residues to the adhesion process. Sequence analysis of the C-terminal amino acid residues of Apa revealed the presence of a putative translocator domain and six conserved HsfBD1-like or HsfBD2-like binding domains. Western blot analysis revealed that the 126 C-terminal amino acids of Apa could form trimeric molecules. By confocal laser scanning microscopy, one of these six domains (ApaBD3) was determined to mediate adherence to epithelial cells. Adherence assays and adherence inhibition assays using a recombinant E. coli- ApaBD3 strain which expressed ApaBD3 on the surface of E. coli confirmed that this domain was responsible for the adhesion activity. Moreover, cellular enzyme-linked immunosorbent assays demonstrated that ApaBD3 mediated high-level adherence to epithelial cell lines. Intriguingly, autoagglutination was observed with the E. coli- ApaBD3 strain, and this phenomenon was dependent upon the association of the expressed ApaBD3 with the C-terminal translocator domain. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. Identification of the Mycobacterium marinum Apa antigen O-mannosylation sites reveals important glycosylation variability with the M. tuberculosis Apa homologue.

    Science.gov (United States)

    Coddeville, Bernadette; Wu, Sz-Wei; Fabre, Emeline; Brassart, Colette; Rombouts, Yoann; Burguière, Adeline; Kremer, Laurent; Khoo, Kay-Hooi; Elass-Rochard, Elisabeth; Guérardel, Yann

    2012-10-22

    The 45/47 kDa Apa, an immuno-dominant antigen secreted by Mycobacterium tuberculosis is O-mannosylated at multiple sites. Glycosylation of Apa plays a key role in colonization and invasion of the host cells by M. tuberculosis through interactions of Apa with the host immune system C-type lectins. Mycobacterium marinum (M.ma) a fish pathogen, phylogenetically close to M. tuberculosis, induces a granulomatous response with features similar to those described for M. tuberculosis in human. Although M.ma possesses an Apa homologue, its glycosylation status is unknown, and whether this represents a crucial element in the pathophysiology induced by M.ma remains to be addressed. To this aim, we have identified two concanavalin A-reactive 45/47 kDa proteins from M.ma, which have been further purified by a two-step anion exchange chromatography process. Advanced liquid chromatography-nanoESI mass spectrometry-based proteomic analyses of peptides, derived from either tryptic digestion alone or in combination with the Asp-N endoproteinase, established that M.ma Apa possesses up to seven distinct O-mannosylated sites with mainly single mannose substitutions, which can be further extended at the Ser/Thr/Pro rich region near the N-terminus. This opens the way to further studies focussing on the involvement and biological functions of Apa O-mannosylation using the M.ma/zebrafish model. Copyright © 2012 Elsevier B.V. All rights reserved.

  3. Investigation of the Asphalt Pavement Analyzer (APA) testing program in Nebraska.

    Science.gov (United States)

    2008-03-01

    The asphalt pavement analyzer (APA) has been widely used to evaluate hot-mix asphalt (HMA) rutting potential in mix : design and quality control-quality assurance (QC-QA) applications, because the APA testing and its data analyses are : relatively si...

  4. The Impact of APA and AERA Guidelines on Effect Size Reporting

    Science.gov (United States)

    Peng, Chao-Ying Joanne; Chen, Li-Ting; Chiang, Hsu-Min; Chiang, Yi-Chen

    2013-01-01

    Given the long history of effect size (ES) indices (Olejnik and Algina, "Contemporary Educational Psychology," 25, 241-286 2000) and various attempts by APA and AERA to encourage the reporting and interpretation of ES to supplement findings from inferential statistical analyses, it is essential to document the impact of APA and AERA standards on…

  5. The Language of Scholarship: How to Rapidly Locate and Avoid Common APA Errors.

    Science.gov (United States)

    Freysteinson, Wyona M; Krepper, Rebecca; Mellott, Susan

    2015-10-01

    This article is relevant for nurses and nursing students who are writing scholarly documents for work, school, or publication and who have a basic understanding of American Psychological Association (APA) style. Common APA errors on the reference list and in citations within the text are reviewed. Methods to quickly find and reduce those errors are shared. Copyright 2015, SLACK Incorporated.

  6. Teaching Scientific Writing: Measuring Student Learning in an Intensive APA Skills Course

    Science.gov (United States)

    Luttrell, Vickie R.; Bufkin, Jana L.; Eastman, Valerie J.; Miller, Robin

    2010-01-01

    The "Publication Manual of the American Psychological Association" (American Psychological Association [APA], 2010) provides a widely utilized template for preparing research reports in the behavioral sciences. Because learning APA style is integral to disciplinary socialization, our department recently implemented a 1-hr course in scientific…

  7. Effects of Test Conditions on APA Rutting and Prediction Modeling for Asphalt Mixtures

    Directory of Open Access Journals (Sweden)

    Hui Wang

    2017-01-01

    Full Text Available APA rutting tests were conducted for six kinds of asphalt mixtures under air-dry and immersing conditions. The influences of test conditions, including load, temperature, air voids, and moisture, on APA rutting depth were analyzed by using grey correlation method, and the APA rutting depth prediction model was established. Results show that the modified asphalt mixtures have bigger rutting depth ratios of air-dry to immersing conditions, indicating that the modified asphalt mixtures have better antirutting properties and water stability than the matrix asphalt mixtures. The grey correlation degrees of temperature, load, air void, and immersing conditions on APA rutting depth decrease successively, which means that temperature is the most significant influencing factor. The proposed indoor APA rutting prediction model has good prediction accuracy, and the correlation coefficient between the predicted and the measured rutting depths is 96.3%.

  8. In-vitro analysis of APA microcapsules for oral delivery of live bacterial cells.

    Science.gov (United States)

    Chen, H; Ouyang, W; Jones, M; Haque, T; Lawuyi, B; Prakash, S

    2005-08-01

    Oral administration of microcapsules containing live bacterial cells has potential as an alternative therapy for several diseases. This article evaluates the suitability of the alginate-poly-L-lysine-alginate (APA) microcapsules for oral delivery of live bacterial cells, in-vitro, using a dynamic simulated human gastro-intestinal (GI) model. Results showed that the APA microcapsules were morphologically stable in the simulated stomach conditions, but did not retain their structural integrity after a 3-day exposure in simulated human GI media. The microbial populations of the tested bacterial cells and the activities of the tested enzymes in the simulated human GI suspension were not substantially altered by the presence of the APA microcapsules, suggesting that there were no significant adverse effects of oral administration of the APA microcapsules on the flora of the human gastrointestinal tract. When the APA microcapsules containing Lactobacillus plantarum 80 (LP80) were challenged in the simulated gastric medium (pH = 2.0), 80.0% of the encapsulated cells remained viable after a 5-min incubation; however, the viability decreased considerably (8.3%) after 15 min and dropped to 2.6% after 30 min and lower than 0.2% after 60 min, indicating the limitations of the currently obtainable APA membrane for oral delivery of live bacteria. Further in-vivo studies are required before conclusions can be made concerning the inadequacy of APA microcapsules for oral delivery of live bacterial cells.

  9. APA/APAGS Award for Distinguished Graduate Student in Professional Psychology: Luz Maria Garcini.

    Science.gov (United States)

    2016-11-01

    The APA/APAGS Award for Distinguished Graduate Student in Professional Psychology is awarded on an annual basis by the APA Board of Professional Affairs (BPA) and the American Psychological Association of Graduate Students (APAGS) to a graduate student who has demonstrated outstanding practice and application of psychology. The 2016 award winners is Luz Maria Garcini, whose commitment to the health and mental health of those recently immigrated has led to research and service that "have greatly benefited the lives of undocumented individuals in the border area of southern California." Garcini's award citation, biography, and a selected bibliography are presented here. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  10. Biomaterials for the programming of cell growth in oral tissues: The possible role of APA.

    Science.gov (United States)

    Salerno, Marco; Giacomelli, Luca; Larosa, Claudio

    2011-01-06

    Examples of programmed tissue response after the interaction of cells with biomaterials are a hot topic in current dental research. We propose here the use of anodic porous alumina (APA) for the programming of cell growth in oral tissues. In particular, APA may trigger cell growth by the controlled release of specific growth factors and/or ions. Moreover, APA may be used as a scaffold to promote generation of new tissue, due to the high interconnectivity of pores and the high surface roughness displayed by this material.

  11. APA/APAGS Award for Distinguished Graduate Student in Professional Psychology: Octavio Andres Santos.

    Science.gov (United States)

    2017-12-01

    The APA/APAGS Award for Distinguished Graduate Student in Professional Psychology is awarded annually by the APA Board of Professional Affairs (BPA) and the American Psychological Association of Graduate Students (APAGS) to a graduate student who has demonstrated outstanding practice and application of psychology. The 2017 award winner is Octavio Andres Santos, who has demonstrated through several initiatives "effective engagement with advocacy, professional organizations, and research in the area of health disparities and multicultural/multilingual assessment." Santos's award citation, biography, and a selected bibliography are presented here. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  12. Adam M. Reid: APA/APAGS Award for Distinguished Graduate Student in Professional Psychology.

    Science.gov (United States)

    2015-11-01

    The APA/APAGS Award for Distinguished Graduate Student in Professional Psychology is awarded on an annual basis by the APA Board of Professional Affairs (BPA) and the American Psychological Association of Graduate Students (APAGS) to a graduate student who has demonstrated outstanding practice and application of psychology. One of the 2015 award winners is Adam M. Reid, who received this award "for his community service, in which he has integrated the highest standards of professional psychological clinical practice and science." Adam's award citation, biography, and a selected bibliography are presented here. (c) 2015 APA, all rights reserved).

  13. Information Technology & Applications Corporation v. United States: An Interested Party's "Substantial Chance" at APA Standing

    National Research Council Canada - National Science Library

    Slicker, Christina

    2003-01-01

    ... of government contracts. The purpose of this paper is not to prove with mathematical certainty that the standing result would be identical whether a court applied the Federal Circuit's "interested party" standard or the APA two-prong test...

  14. [Exercise-referral to a specialist in adapted physical activity (APA) : a pilot project].

    Science.gov (United States)

    Brugnerotto, Adeline; Cardinaux, Regula; Ueltschi, Yan; Bauwens, Marine; Nanchen, David; Cornuz, Jacques; Bize, Raphaël; Auer, Reto

    2016-11-02

    Family physicians have a key role in the promotion of physical activity, in particular in identifying and counseling persons who have a sedentary lifestyle. Some patients could benefit from intensive individual counseling. Physicians are often not aware of all physical activity promotion activities in the community that they could recommend their patients. In a pilot study, we have tested and adapted the referral of patients from family physicians to specialists in adapted physical activity (APAs). APAs are trained to assess and guide persons towards physical activities adapted to their needs and pathologies and thus towards an increase in physical activity. Pilot data suggest that, while few patients were oriented to the APAs in the pilot project, family physicians appreciate the possibility of collaborating with the APAs.

  15. Michael K. Scullin: Psi Chi/APA Edwin B. Newman Graduate Research Award.

    Science.gov (United States)

    2011-11-01

    Presents Michael K. Scullin as the 2011 winner of the American Psychological Association Psi Chi/APA Edwin B. Newman Graduate Research Award. "For an outstanding research paper that examines the relationship between prospective memory in executing a goal and various lapses of time from 20 minutes up to a 12- hour wake delay and a 12-hour sleep delay. The results suggest that consolidation processes active during sleep increase the probability of goal execution. The paper, titled 'Remembering to Execute a Goal: Sleep On It!' was published in Psychological Science in 2010 and was the basis for Michael K. Scullin's selection as the recipient of the 2011 Psi Chi/APA Edwin B. Newman Graduate Research Award. Mark A. McDaniel, PhD, served as faculty research advisor." (PsycINFO Database Record (c) 2011 APA, all rights reserved). 2011 APA, all rights reserved

  16. Linkage disequilibrium at the APA insecticidal seed protein locus of common bean (Phaseolus vulgaris L.).

    Science.gov (United States)

    Blair, Matthew W; Prieto, Sergio; Díaz, Lucy M; Buendía, Héctor F; Cardona, César

    2010-04-29

    An interesting seed protein family with a role in preventing insect herbivory is the multi-gene, APA family encoding the alpha-amylase inhibitor, phytohemagglutinin and arcelin proteins of common bean (Phaseolus vulgaris). Variability for this gene family exists and has been exploited to breed for insect resistance. For example, the arcelin locus has been successfully transferred from wild to cultivated common bean genotypes to provide resistance against the bruchid species Zabrotes subfasciatus although the process has been hampered by a lack of genetic tools for and understanding about the locus. In this study, we analyzed linkage disequilibrium (LD) between microsatellite markers at the APA locus and bruchid resistance in a germplasm survey of 105 resistant and susceptible genotypes and compared this with LD in other parts of the genome. Microsatellite allele diversity was found to vary with each of the eight APA-linked markers analyzed, and two markers within the APA locus were found to be diagnostic for bruchid resistance or susceptibility and for the different arcelin alleles inherited from the wild accessions. Arc1 was found to provide higher levels of resistance than Arc5 and the markers in the APA locus were highly associated with resistance showing that introgression of this gene-family from wild beans provides resistance in cultivated beans. LD around the APA locus was found to be intermediate compared to other regions of the genome and the highest LD was found within the APA locus itself for example between the markers PV-atct001 and PV-ag004. We found the APA locus to be an important genetic determinant of bruchid resistance and also found that LD existed mostly within the APA locus but not beyond it. Moderate LD was also found for some other regions of the genome perhaps related to domestication genes. The LD pattern may reflect the introgression of arcelin from the wild into the cultivated background through breeding. LD and association studies for

  17. APA Handbook of Industrial and Organizational Psychology. Three-Volume Set--Volume 1: Building and Developing the Organization. Volume 2: Selecting and Developing Members for the Organization. Volume 3: Maintaining, Expanding, and Contracting the Organization. APA Handbooks in Psychology Series. APA Reference Books Collection

    Science.gov (United States)

    Zedeck, Sheldon, Ed.

    2011-01-01

    APA Books® announces the "APA Handbook of Industrial and Organizational Psychology"--the first offering in an new reference series covering core and emerging subdisciplines, the "APA Handbooks in Psychology." I/O Psychology is both a science/practice and an applied/basic research discipline. Appropriately, the "APA…

  18. Biological changes of APA-BCC analgesic microcapsule in cerebrospinal fluid of patients with carcinomatous pain

    International Nuclear Information System (INIS)

    Luo Yun; Li Yanling; Xue Yilong; Guo Shulong; Gao Yuhong; Cui Xin

    2005-01-01

    To explore the changes of alginate-polylysine-alginate microcapsulated bovine adrenal medullary chromaffin cells (APA-BCC microcapsules) in morphology, survival rate and leucine- enkephalin secretion after they were transplanted into CSF of cancerpain patients, the APA- BCC microcapsules were Implanted into cavitas subarachnoidealis of cancer-pain patients by conventional lumbar puncture. After 7 or 8 days, cerebrospinal fluid was collected and the morphology of the APA-BCC microcapsule, the survival rate of cells were observed and secretory volume of leucine-enkephalin was assayed by radioimmunity method. Seven days after trans- plantation, the mean VAS decreased from 8.8 to 2.4, the survival rate of cells averagely reduced from 91.2% to 89.1%, morphology of APA-BCC microcapsules did not change obviously and secretory volume of leucine-enkephalin went up 1.65 times compared with that at pretrans- plantation. In conclusion, APA-BCC can survive, secret leucine-enkephalin and produce analgesic effect after transplanted into CSF of cancer-patients. (authors)

  19. Plutonium and minor actinides recycling in PWRs with new APA concepts

    International Nuclear Information System (INIS)

    Golfier, H.; Rohart, M.; Aniel, S.; Bergeron, J.; Deffain, J.P.

    2001-01-01

    In the frame of the studies required by the French law of 1991, CEA have launched a wide range of assessments on waste management for different reactors (PWR, FBR). Considerable R and D work has already been performed in order to improve the use of Plutonium (Pu) in PWRs. In this context, the Advanced Plutonium Assembly (APA) aims to improve the use of Plutonium (Pu) in PWRs while minimizing Minor Actinides (MA) production, with only slight modifications of the core design. From a neutronic point of view, the overall studied cases lead to the stabilization of the Pu inventory with approximately 30% of the park refueled with APA assemblies in full APA cores. Multi-recycling could satisfy the stabilization of Pu+ (Am+Cm) inventory by the implementation of approximately 40% APA reactors in a conventional PWRs park. After 7 or 8 recycles, the equilibrium is reached. The Pu inventory in the fuel cycle ranges from 210 tons to 270 tons for Pu multi-recycling, and from 240 tons to 290 tons for Pu+(Am+Cm) multi-recycling. The saving in Natural Uranium and Separative Work Units (SWU) due to the use of APA reactors would be between 30% and 15% in comparison with the UO 2 open cycle. This paper presents a selection of the main preliminary Pu recycling results of the joint study program COGEMA-CEA. (author)

  20. Allie Abrahamson: APA/APAGS Award for Distinguished Graduate Student in Professional Psychology.

    Science.gov (United States)

    2014-11-01

    The APA/APAGS Award for Distinguished Graduate Student in Professional Psychology is awarded on an annual basis by the APA Board of Professional Affairs (BPA) and the American Psychological Association of Graduate Students (APAGS) to a graduate student who has demonstrated outstanding practice and application of psychology. A qualified candidate must demonstrate exemplary performance in working with an underserved population in an applied setting or have developed an innovative method for delivering health services to an underserved population. This year there are joint recipients of the award, Allie Abrahamson and Rebeccah A. Bernard. Their vision, creativity, courage, and dedication led them to create the Human Rights Forum at Chestnut Hill College to promote human rights education, awareness, and community service opportunities for doctoral students. Allie Abrahamson's award citation, biography, and a selected bibliography are presented here. PsycINFO Database Record (c) 2014 APA, all rights reserved.

  1. Rebeccah A. Bernard: APA/APAGS Award for Distinguished Graduate Student in Professional Psychology.

    Science.gov (United States)

    2014-11-01

    The APA/APAGS Award for Distinguished Graduate Student in Professional Psychology is awarded on an annual basis by the APA Board of Professional Affairs (BPA) and the American Psychological Association of Graduate Students (APAGS) to a graduate student who has demonstrated outstanding practice and application of psychology. A qualified candidate must demonstrate exemplary performance in working with an underserved population in an applied setting or have developed an innovative method for delivering health services to an underserved population. This year there are joint recipients of the award, Allie Abrahamson and Rebeccah A. Bernard. Their vision, creativity, courage, and dedication led them to create the Human Rights Forum at Chestnut Hill College to promote human rights education, awareness, and community service opportunities for doctoral students. Rebeccah A. Bernard's award citation, biography, and a selected bibliography are presented here. PsycINFO Database Record (c) 2014 APA, all rights reserved.

  2. Jordan M. Braciszewski: APA/APAGS Award for Distinguished Graduate Student in Professional Psychology.

    Science.gov (United States)

    2011-11-01

    Presents Jordan M. Braciszewski as the 2011 winner of the American psychological Association APA/APAGS Award for Distinguished Graduate Student in Professional Psychology. "For his concerted efforts to identify the needs of homeless and other at-risk populations and to design and provide necessary services for them. Jordan M. Braciszewski is committed to using applied psychological science and evidence-based intervention methods to assist the most disadvantaged in our society. He has already provided additions to the relevant research literature and has volunteered countless hours of his time to implement community-based interventions and provide direct services himself. He has sought out the training experiences necessary to assist him in doing an even better job in the future in these public service activities." (PsycINFO Database Record (c) 2011 APA, all rights reserved). 2011 APA, all rights reserved

  3. Aquatic toxicity and biodegradability of advanced cationic surfactant APA-22 compatible with the aquatic environment.

    Science.gov (United States)

    Yamane, Masayuki; Toyo, Takamasa; Inoue, Katsuhisa; Sakai, Takaya; Kaneko, Youhei; Nishiyama, Naohiro

    2008-01-01

    Cationic surfactant is a chemical substance used in hair conditioner, fabric softener and other household products. By investigating the relationship between the aquatic toxicity and the chemical structures of two types of mono alkyl cationic surfactants, alkyl trimethylammonium salts and alkyl dimethylamine salts, we have found that the C22 alkyl chain length is effective to reduce the toxicity. Besides, we have recognized that the amidopropyl functional group contributes to the enhanced biodegradability by investigating the biodegradation trend of (alkylamidopropyl)dimethylamine salt (alkyl chain length: C18). Based on these findings, we have developed mono alkyl cationic surfactant called APA-22, N-[3-(dimethylamino)propyl]docosanamide salt. APA-22 is formed by the C22 alkyl chain, amidopropyl functional group and di-methyltertiary amine group. We evaluated the aerobic and anaerobic biodegradability of APA-22 by two standard methods (OECD Test Guideline 301B and ECETOC technical document No.28) and found that this substance was degraded rapidly in both conditions. The toxicity to algae, invertebrate and fish of this substance are evaluated by using OECD Test Guideline 201, 202 and 203, respectively. All acute toxicity values are >1 mg/L, which indicates that environmental toxicity of this substance is relatively less toxic to aquatic organism. In addition, we estimated the biodegradation pathway of APA-22 and observed the complete disappearance of APA-22 and its intermediates during the test periods. Based on the environmental data provided above, we concluded that APA22 is more compatible with the aquatic environment compared to other cationic surfactants with mono long alkyl chain.

  4. Molecular Regulation of Alternative Polyadenylation (APA) within the Drosophila Nervous System.

    Science.gov (United States)

    Vallejos Baier, Raul; Picao-Osorio, Joao; Alonso, Claudio R

    2017-10-27

    Alternative polyadenylation (APA) is a widespread gene regulatory mechanism that generates mRNAs with different 3'-ends, allowing them to interact with different sets of RNA regulators such as microRNAs and RNA-binding proteins. Recent studies have shown that during development, neural tissues produce mRNAs with particularly long 3'UTRs, suggesting that such extensions might be important for neural development and function. Despite this, the mechanisms underlying neural APA are not well understood. Here, we investigate this problem within the Drosophila nervous system, focusing on the roles played by general cleavage and polyadenylation factors (CPA factors). In particular, we examine the model that modulations in CPA factor concentration may affect APA during development. For this, we first analyse the expression of the Drosophila orthologues of all mammalian CPA factors and note that their expression decreases during embryogenesis. In contrast to this global developmental decrease in CPA factor expression, we see that cleavage factor I (CFI) expression is actually elevated in the late embryonic central nervous system, suggesting that CFI might play a special role in neural tissues. To test this, we use the UAS/Gal4 system to deplete CFI proteins from neural tissue and observe that in this condition, multiple genes switch their APA patterns, demonstrating a role of CFI in APA control during Drosophila neural development. Furthermore, analysis of genes with 3'UTR extensions of different length leads us to suggest a novel relation between 3'UTR length and sensitivity to CPA factor expression. Our work thus contributes to the understanding of the mechanisms of APA control within the developing central nervous system. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  5. Connor H. G. Patros: Psi Chi/APA Edwin B. Newman Graduate Research Award.

    Science.gov (United States)

    2015-11-01

    The Edwin B. Newman Graduate Research Award is given jointly by Psi Chi and APA. The award was established to recognize young researchers at the beginning of their professional lives and to commemorate both the 50th anniversary of Psi Chi and the 100th anniversary of psychology as a science (dating from the founding of Wundt's laboratory). The 2015 recipient is Connor H. G Patros. Patros was chosen for "an excellent research paper that examines the complex relationship between working memory, choice-impulsivity, and the attention-deficit/hyperactivity disorder (ADHD) phenotype." Patros's award citation, biography, and a selected bibliography are presented here. (c) 2015 APA, all rights reserved).

  6. seed storage proteins arl2 and its variants from the apa locus of wild ...

    African Journals Online (AJOL)

    sion of arcelin and ARL2 tepary bean proteins. Furthermore, a reduction in size and weight of emerged adult insects to almost half was observed. This work demonstrates the superior resistance common bean backcross lines to A. obtectus conferred by the presence of the APA proteins introgressed from tepary bean.

  7. Psi Chi/APA Edwin B. Newman Graduate Research Award: Joseph H. Hammer

    Science.gov (United States)

    American Psychologist, 2009

    2009-01-01

    Joseph H. Hammer, recipient of the Psi Chi/APA Edwin B. Newman Graduate Research Award, is cited for an outstanding research paper whose findings provide important evidence regarding the promise of a male-sensitive approach to mental health marketing and empirically support the inclusion of theory-driven enhancements in group-targeted mental…

  8. Utilizaci??n de la normativa APA 6?? edici??n

    OpenAIRE

    Justicia-Arr??ez, Ana

    2016-01-01

    Tomando como referencia la normativa APA en su 6?? edici??n publicada en 2010 en el Manual of the American Psychological Association (6th ed.) por la American Psychological Association, se presenta una gu??a pr??ctica dirigida al alumnado de Ciencias de la Educaci??n.

  9. APA Reporting Standards in Quantitative Research Dissertations from an Online EdD Program

    Science.gov (United States)

    Salgado, Griselle

    2013-01-01

    This study was an investigation of the reporting practices in dissertations with quantitative research designs produced by students enrolled in an online Doctor of Education (EdD) program, one that follows the American Psychological Association (APA) standards for reporting research. Limited, empirical information exists about the competencies in…

  10. APA/APAGS Award for Distinguished Graduate Student in Professional Psychology.

    Science.gov (United States)

    2017-12-01

    The APA/APAGS Award for Distinguished Graduate Student in Professional Psychology is awarded on an annual basis by the APA Board of Professional Affairs (BPA) and the American Psychological Association of Graduate Students (APAGS) to a graduate student who has demonstrated outstanding practice and application of psychology. A qualified candidate must demonstrate exemplary performance in working with an underserved population in an applied setting or have developed an innovative method for delivering health services to an underserved population. The 2017 recipient of the APA/APAGS Award for Distinguished Graduate Student in Professional Psychology was selected by the 2016 Board of Professional Affairs (BPA) and the 2016 APAGS Scholarship and Awards Selection Committee. Members of the 2016 BPA were Antonette M. Zeiss, PhD (Chair); Linda A. Reddy, PhD; Lois O. Condie, PhD; Timothy A. Cavell, PhD; Robert T. Kinscherff, PhD, JD; Jared L. Skillings, PhD, ABPP; Cynthia A. Gómez, PhD; Lisa K. Kearney, PhD, ABPP; and Dinelia Rosa, PhD. Members of the 2016 APAGS Scholarship and Awards Selection Committee were Jerrold Yeo, MA; Jacklynn Fitzgerald, MA; and Roseann Fish Getchell, MA, Med. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  11. Research Productivity and Scholarly Impact of APA-Accredited School Psychology Programs: 2005-2009

    Science.gov (United States)

    Kranzler, John H.; Grapin, Sally L.; Daley, Matt L.

    2011-01-01

    This study examined the research productivity and scholarly impact of faculty in APA-accredited school psychology programs using data in the PsycINFO database from 2005 to 2009. We ranked doctoral programs on the basis of authorship credit, number of publications, and number of citations. In addition, we examined the primary publication outlets of…

  12. APA's Learning Objectives for Research Methods and Statistics in Practice: A Multimethod Analysis

    Science.gov (United States)

    Tomcho, Thomas J.; Rice, Diana; Foels, Rob; Folmsbee, Leah; Vladescu, Jason; Lissman, Rachel; Matulewicz, Ryan; Bopp, Kara

    2009-01-01

    Research methods and statistics courses constitute a core undergraduate psychology requirement. We analyzed course syllabi and faculty self-reported coverage of both research methods and statistics course learning objectives to assess the concordance with APA's learning objectives (American Psychological Association, 2007). We obtained a sample of…

  13. Scholarly Productivity and Impact of School Psychology Faculty in APA-Accredited Programs

    Science.gov (United States)

    Grapin, Sally L.; Kranzler, John H.; Daley, Matt L.

    2013-01-01

    The primary objective of this study was to conduct a normative assessment of the research productivity and scholarly impact of tenured and tenure-track faculty in school psychology programs accredited by the American Psychological Association (APA). Using the PsycINFO database, productivity and impact were examined for the field as a whole and by…

  14. IAP/APA evidence-based guidelines for the management of acute pancreatitis

    NARCIS (Netherlands)

    Goor, H. van; et al.,

    2013-01-01

    BACKGROUND: There have been substantial improvements in the management of acute pancreatitis since the publication of the International Association of Pancreatology (IAP) treatment guidelines in 2002. A collaboration of the IAP and the American Pancreatic Association (APA) was undertaken to revise

  15. IAP/APA evidence-based guidelines for the management of acute pancreatitis

    NARCIS (Netherlands)

    Besselink, Marc; van Santvoort, Hjalmar; Freeman, Martin; Gardner, Timothy; Mayerle, Julia; Vege, Santhi Swaroop; Werner, Jens; Banks, Peter; McKay, Colin; Fernandez-del Castillo, Carlos; French, Jeremy; Gooszen, Hein; Johnson, Colin; Sarr, Mike; Takada, Tadahiro; Windsor, John; Saluja, Ashok; Liddle, Rodger; Papachristou, Georgios; Singh, Vijay; Rünzi, Michael; Wu, Bechien; Singh, Vikesh; Bollen, Thomas; Morgan, Desiree; Mortele, Koenraad; Mittal, Anubhav; En-qiang, Mao; de Waele, Jan; Petrov, Maxim; Dellinger, Patchen; Lerch, Markus M.; Anderson, Roland; McClave, Stephen; Hartwig, Werner; Bruno, Marco; Oria, Alejandro; Baron, Todd; Castillo, Carlos Fernandez-Del; Fagenholz, Peter; Horvath, Karen; van Baal, Mark; Nealon, William; Andren-Sandberg, Ake; Bakker, Olaf; Bassi, Claudio; Buchler, Markus; Boermeester, Marja; Bradley, Ed; Fockens, Paul

    2013-01-01

    There have been substantial improvements in the management of acute pancreatitis since the publication of the International Association of Pancreatology (IAP) treatment guidelines in 2002. A collaboration of the IAP and the American Pancreatic Association (APA) was undertaken to revise these

  16. Internship Attainment and Program Policies: Trends in APA-Accredited School Psychology Programs

    Science.gov (United States)

    Perfect, Michelle M.; Thompson, Miriam E.; Mahoney, Emery

    2015-01-01

    Completion of an internship that is accredited by the American Psychological Association (APA) is considered to be to the "gold standard" for health service psychology training programs. The Association of Psychology Postdoctoral and Internship Centers (APPIC) facilitates a Match process between participating applicants and internship…

  17. Cynthia J. Najdowski: Psi Chi/APA Edwin B. Newman Graduate Research Award

    Science.gov (United States)

    American Psychologist, 2012

    2012-01-01

    Presents a short biography of the winner of the American Psychological Association's Psi Chi/APA Edwin B. Newman Graduate Research Award. The 2012 winner is Cynthia J. Najdowski for an outstanding research paper that examines how jurors' judgments are influenced by a juvenile defendant's confession and status as intellectually disabled. Through…

  18. Effects of an Interteaching Probe on Learning and Generalization of American Psychological Association (APA) Style

    Science.gov (United States)

    Slezak, Jonathan M.; Faas, Caitlin

    2017-01-01

    This study implemented the components of interteaching as a probe to teach American Psychological Association (APA) Style to undergraduate university students in a psychology research methods and statistics course. The interteaching method was compared to the traditional lecture-based approach between two sections of the course with the same…

  19. APA/APAGS Award for Distinguished Graduate Student in Professional Psychology.

    Science.gov (United States)

    2016-11-01

    The APA/APAGS Award for Distinguished Graduate Student in Professional Psychology is awarded on an annual basis by the APA Board of Professional Affairs (BPA) and the American Psychological Association of Graduate Students (APAGS) to a graduate student who has demonstrated outstanding practice and application of psychology. A qualified candidate must demonstrate exemplary performance in working with an underserved population in an applied setting or have developed an innovative method for delivering health services to an underserved population. The 2016 recipient of the APA/APAGS Award for Distinguished Graduate Student in Professional Psychology was selected by the 2015 Board of Professional Affairs (BPA) and the 2015 APAGS Scholarship and Awards Selection Committee. Members of the 2015 BPA were Patricia Arredondo, EdD; Helen L. Coons, PhD, ABPP; Vickie Mays, PhD, MSPH; Linda A. Reddy, PhD; Lois O. Condi, PhD; Antonette M. Zeiss, PhD; Timothy A. Cavell, PhD; Robert T. Kinscherff, PhD, JD; and Jared L. Skillings, PhD, ABPP. Members of the 2015 APAGS Scholarship and Awards Selection Committee were Emily Voelkel, PhD; Blaire Schembari; and Yolanda Perkins-Volk. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  20. An Assessment of Reliability and Validity of a Rubric for Grading APA-Style Introductions

    Science.gov (United States)

    Stellmack, Mark A.; Konheim-Kalkstein, Yasmine L.; Manor, Julia E.; Massey, Abigail R.; Schmitz, Julie Ann P.

    2009-01-01

    This article describes the empirical evaluation of the reliability and validity of a grading rubric for grading APA-style introductions of undergraduate students. Levels of interrater agreement and intrarater agreement were not extremely high but were similar to values reported in the literature for comparably structured rubrics. Rank-order…

  1. Construction of doxycycline-mediated BMP-2 transgene combining with APA microcapsules for bone repair.

    Science.gov (United States)

    Qian, Dongyang; Bai, Bo; Yan, Guangbin; Zhang, Shujiang; Liu, Qi; Chen, Yi; Tan, Xiaobo; Zeng, Yanjun

    2016-01-01

    The repairing of large segmental bone defects is difficult for clinical orthopedists at present. Gene therapy is regarded as a promising method for bone defects repair. The present study aimed to construct an effective and controllable Tet-On expression system for transferring hBMP-2 gene into bone marrow mesenchymal progenitor cells (BMSCs). Meanwhile, with combination of alginate-poly-L-lysine-alginate (APA) microencapsulation technology, we attempted to reduce the influence of immunologic rejection and examine the effect of the Tet-On expression system on osteogenesis of BMSCs. The adenovirus encoding hBMP-2 (ADV-hBMP2) was constructed using the means of molecular cloning. The ADV-hBMP2 and Adeno-X Tet-On virus was respectively transfected to the HEK293 for amplification and afterward BMSCs were co-infected with the virus of ADV-hBMP2 and the Adeno-X Tet-On. The expression of hBMP-2 was measured with induction by doxycycline (DOX) at different concentration by means of RT-PCR and ELISA. Combining Tet-On expression system and APA microcapsules with the use of the pulsed high-voltage electrostatic microcapsule instrument, we examined the expression level of hBMP-2 in APA microcapsules by ELISA as well as the osteogenesis by alizarin red S staining. An effective Tet-On expression system for transferring hBMP-2 gene into BMSCs was constructed successfully. Also, the expression of hBMP-2 could be regulated by concentration of DOX. The data exhibited that BMSCs in APA microcapsules maintained the capability of proliferation and differentiation. The combination of Tet-On expression system and APA microcapsules could promote the osteogenesis of BMSCs. According to the results, microencapsulated Tet-On expression system showed the effective characteristics of secreting hBMP-2 and enhancing osteogenesis, which would provide a promising way for bone repair.

  2. Caveats in the proficient preparation of an APA-style research manuscript for publication.

    Science.gov (United States)

    Cash, Thomas F

    2009-01-01

    Writing a scientific research paper for submission to a peer-reviewed journal requires compositional skill and attention to details. In evaluating submitted manuscripts, journal editors and reviewers often encounter recurrent mistakes in composition and in compliance with the stylistic requirements of the particular publication. This editorial article identifies core tenets of effective scientific writing in the social and behavioral sciences, and it delineates commonly committed errors in violation of the style prescribed by the American Psychological Association (APA). The editor organizes his advice in a user-friendly checklist to assist both authors and reviewers associated with this journal (Body Image: An International Journal of Research), as well as other journals that adhere to APA style. This advisory article may also assist research supervisors and instructors in academic training contexts.

  3. APA/Psi Chi Edwin B. Newman Graduate Research Award: Meghan H. Puglia.

    Science.gov (United States)

    2016-11-01

    The Edwin B. Newman Graduate Research Award is given jointly by Psi Chi and APA. The award was established to recognize young researchers at the beginning of their professional lives and to commemorate both the 50th anniversary of Psi Chi and the 100th anniversary of psychology as a science (dating from the founding of Wundt's laboratory). The 2016 recipient is Meghan H. Puglia, who was chosen for "an outstanding foundational research paper that establishes a relationship between a functional epigenetic modification to the oxytocin receptor gene (OXTR) and neural response during social perception." Puglia's award citation, biography, and bibliography are presented here. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  4. Grounding Hypnosis in Science: The 'New' APA Division 30 definition of hypnosis as a step backwards.

    OpenAIRE

    Lynn, Stephen Jay; Green, Joseph P.; Kirsch , Irving; Capafons, Antonio; Lilienfeld, .S.OScott O; Laurence, Jean R.; Montgomery, Guy H.

    2015-01-01

    Every decade or so, the Division 30 of the American Psychological Association (APA) has seen fit to redefine hypnosis (Elkins, Barabasz, Council, & Spiegel, 2015; Green, Barabasz, Barrett, & Montgomery, 2005; Kirsch, 1994). In the latest attempt, the Hypnosis Definition Committee (HDC) defined hypnosis as a 'state of consciousness involving focused attention and reduced peripheral awareness characterized by an enhanced capacity for response to suggestion' (Elkins et al., 2015, p. 6). One migh...

  5. Synthesis and properties of ApA analogues with shortened phosphonate internucleotide linkage

    Czech Academy of Sciences Publication Activity Database

    Králíková, Šárka; Buděšínský, Miloš; Barvík, I.; Masojídková, Milena; Točík, Zdeněk; Rosenberg, Ivan

    2011-01-01

    Roč. 30, 7/9 (2011), s. 524-543 ISSN 1525-7770 R&D Projects: GA ČR GA202/09/0193; GA AV ČR KAN200520801; GA MŠk(CZ) LC06061 Institutional research plan: CEZ:AV0Z40550506 Keywords : alpha-hydroxy-phosphonate linkage * ApA analogues * phosphonate internucleotide bond * NMR conformational study Subject RIV: CC - Organic Chemistry Impact factor: 0.899, year: 2011

  6. Oscillatory transenantiomerization of the selected 2-arylpropionic acid (2-APAs) in vitro as a spontaneous phenomenon

    International Nuclear Information System (INIS)

    Sajewicz, M.; Alska, T.K.

    2006-01-01

    In this paper, we summarize the results of our earlier investigations on an attempted enantioseparation of the selected 2-arylpropionic acids (2-APAs) by means of the chiral thin layer chromatography (TLC). These results have been originally presented in a series of the research papers published in several chromatography journals. In the current article it was reminded that the prolonged storage of the investigated 2-APAs in the aqueous and the non-aqueous solutions results in an oscillatory change of the respective retardation factor (RF) and the specific rotation (alfa)/sub P/) values. An assumption is introduced as to the chemical nature of the observed phenomenon. It is assumed that the observed oscillations are due to the repeated structural inversion (in our study labelled as oscillatory transenantiomerization) of one enantiomer to its respective antimer. One attempts to at least roughly explain the molecular mechanism of transenantiomerization either by keto-enol tautomerism, or by formation of an intermediate enolic anion, any of these two reaction mechanisms possible only in the basic environment. Then one reflects on the most probable mechanism responsible for the oscillatory nature of the observed structural inversion. It is concluded that the oscillations could be due to an enhanced viscosity of the investigated 2-APA solutions (as compared with those of the respective pure solvents) and/or due to the molecular self-organization within these solutions, resulting in anisotropic properties thereof. Finally, it is concluded that an ultimate explanation of the observed oscillatory transenantiomerization of the selected 2-APAs could probably be offered by the Brusselator-type kinetic model implemented with the diffusion term. In the last section of this paper, argumentation is presented strongly in favour of this particular model and against any alternative speculation as to the supramolecular nature of the observed oscillatory phenomena. (author)

  7. APA Award for Distinguished Professional Contributions to Applied Research: Cameron J. Camp.

    Science.gov (United States)

    2017-12-01

    The Award for Distinguished Professional Contributions to Applied Research is given to a psychologist whose research has led to important discoveries or developments in the field of applied psychology. The 2017 recipient is Cameron J. Camp, whose innovative programs have informed psychologists in working with dementia patients to improve their living skills and enhance their independence. Camp's award citation, biography, and a selected bibliography are presented here. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  8. Informed Consent and Clinical Research Involving Children and Adolescents: Implications of the Revised APA Ethics Code and HIPAA

    Science.gov (United States)

    Fisher, Celia B.

    2004-01-01

    In 2003, 2 new sets of rules and regulations affecting the conduct of clinical research involving children and adolescents went into effect: the revised American Psychological Association's (APA) Ethical Principles of Psychologists and Code of Conduct (APA, 2002; effective June 1, 2003) and the Privacy Rule (45 CFR Part 160 and A and E of Part…

  9. Cynthia J. Najdowski: Psi Chi/APA Edwin B. Newman Graduate Research Award.

    Science.gov (United States)

    2012-11-01

    Presents a short biography of the winner of the American Psychological Association's Psi Chi/APA Edwin B. Newman Graduate Research Award. The 2012 winner is Cynthia J. Najdowski for an outstanding research paper that examines how jurors' judgments are influenced by a juvenile defendant's confession and status as intellectually disabled. Through the use of a mock trial experiment, the research revealed that jurors discounted a juvenile's coerced confession and sometimes used intellectual disability as a mitigating factor. Attribution theory and the discounting principle were used to identify the psychological mechanisms underlying this effect. The paper, titled 'Understanding Jurors' Judgments in Cases Involving Juvenile Defendants,' was published in Psychology, Public Policy, and Law in October 2011 and was the basis for Najdowski's selection as the recipient of the 2012 Psi Chi/APA Edwin B. Newman Graduate Research Award. Bette L. Bottoms, PhD, served as faculty supervisor. Najdowski's Award citation and a selected bibliography are also presented. PsycINFO Database Record (c) 2012 APA, all rights reserved.

  10. IAP/APA evidence-based guidelines for the management of acute pancreatitis.

    Science.gov (United States)

    2013-01-01

    There have been substantial improvements in the management of acute pancreatitis since the publication of the International Association of Pancreatology (IAP) treatment guidelines in 2002. A collaboration of the IAP and the American Pancreatic Association (APA) was undertaken to revise these guidelines using an evidence-based approach. Twelve multidisciplinary review groups performed systematic literature reviews to answer 38 predefined clinical questions. Recommendations were graded using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. The review groups presented their recommendations during the 2012 joint IAP/APA meeting. At this one-day, interactive conference, relevant remarks were voiced and overall agreement on each recommendation was quantified using plenary voting. The 38 recommendations covered 12 topics related to the clinical management of acute pancreatitis: A) diagnosis of acute pancreatitis and etiology, B) prognostication/predicting severity, C) imaging, D) fluid therapy, E) intensive care management, F) preventing infectious complications, G) nutritional support, H) biliary tract management, I) indications for intervention in necrotizing pancreatitis, J) timing of intervention in necrotizing pancreatitis, K) intervention strategies in necrotizing pancreatitis, and L) timing of cholecystectomy. Using the GRADE system, 21 of the 38 (55%) recommendations, were rated as 'strong' and plenary voting revealed 'strong agreement' for 34 (89%) recommendations. The 2012 IAP/APA guidelines provide recommendations concerning key aspects of medical and surgical management of acute pancreatitis based on the currently available evidence. These recommendations should serve as a reference standard for current management and guide future clinical research on acute pancreatitis. Copyright © 2013 IAP and EPC. Published by Elsevier B.V. All rights reserved.

  11. cis-Apa: a practical linker for the microwave-assisted preparation of cyclic pseudopeptides via RCM cyclative cleavage.

    Science.gov (United States)

    Baron, Alice; Verdié, Pascal; Martinez, Jean; Lamaty, Frédéric

    2011-02-04

    A new linker cis-5-aminopent-3-enoic acid (cis-Apa) was prepared for the synthesis of cyclic pseudopeptides by cyclization-cleavage by using ring-closing methatesis (RCM). We developed a new synthetic pathway for the preparation of the cis-Apa linker that was tested in the cyclization-cleavage process of different RGD peptide sequences. Different macrocyclic peptidomimetics were prepared by using this integrated microwave-assisted method, showing that the readily available cis-Apa amino acid is well adapted as a linker in the cyclization-cleavage process.

  12. [Study on relationship of dose-effect and time-effect of APA microencapsulated bovine chromaffin cells on pain treatment].

    Science.gov (United States)

    Hui, Jianfeng; Li, Tao; Du, Zhi; Song, Jichang

    2011-12-01

    This study was to investigate the relationship of dose-effect and time-effect of Alginate-Polylysine-Alginate (APA) microencapsulated bovine chromaffin cells on the treatment of pain model rats. Using a rat model of painful peripheral neuropathy, the antinociceptive effects of APA microencapsulated bovine cells transplanted into the subarachnoid space was evaluated by cold allodynia test and hot hyperalgesia test. Compared with control group, the withdrawal difference with cell number 50 thousands groups, 100 thousands groups and 200 thousands groups was reduced (P APA microencapsulated bovine chromaffin cells which were transplanted to treat pain model rats, and the effective antinociception remained longer than 12 weeks.

  13. Advanced plutonium assembly (apa): evolution of the concept, neutron and thermal-mechanic constraints

    International Nuclear Information System (INIS)

    Porta, J.; Gastaldi, B.; Krakowiak-Aillaud, C.; Buffe, L.

    2002-01-01

    The APA concept was developed with the aim of increasing the PWR capacity to burn plutonium emerging from the recycling of irradiated fuels in the French park of nuclear power plants. At first, a concept using annular pins was optimised to allow a good consumption of plutonium while preserving an acceptable neutron control. To cope with the technological problems and those posed by the manufacture of these annular pins, an alternative concept is presented here. It poses as initial conditions the conservation of both the plutonium balance and the respect of the reactivity control. (authors)

  14. Complementing the Latest APA Definition of Hypnosis: Sensory-Motor and Vascular Peculiarities Involved in Hypnotizability.

    Science.gov (United States)

    Santarcangelo, Enrica L; Scattina, Eliana

    2016-01-01

    The aim of this article is to complement the recently revised American Psychological Association (APA) definition of hypnotizability. It (a) lists a few differences in sensorimotor integration between subjects with high (highs) and low (lows) hypnotizability scores in the ordinary state of consciousness and in the absence of suggestions, (b) proposes that hypnotizability-related cerebellar peculiarities may account for them, (c) suggests that the cerebellum could also be involved in cognitive aspects of hypnotizability and (d) explains why the information derived from studies of sensorimotor and cardiovascular aspects of hypnotizability may be relevant to its definition and useful in orienting further experimental research in the field of hypnosis.

  15. APA/Psi Chi Edwin B. Newman Graduate Research Award: Samantha F. Anderson.

    Science.gov (United States)

    2017-12-01

    The Edwin B. Newman Graduate Research Award is given jointly by Psi Chi and the American Psychological Association. The award was established to recognize young researchers at the beginning of their professional lives and to commemorate both the 50th anniversary of Psi Chi and the 100th anniversary of psychology as a science (dating from the founding of Wundt's laboratory). The 2017 recipient is Samantha F. Anderson, who was chosen for "an exceptional research paper that responds to psychology's 'replication crisis' by outlining a broader view of success in replication." Her award citation, biography, and a selected bibliography are presented here. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  16. Academic Practice, APA Referencing Style:guidelines for staff and students

    OpenAIRE

    Nielsen, Sandro; Heine, Carmen

    2017-01-01

    Vejledning i at undgå plagiering ved at følge de normer, der gælder for good academic practice. Dette indebærer at man angiver kilder korrekt, og når det er nødvendigt, og at man har en korrekt udformet fortegnelse over referencer. Vejledningen indeholder konkrete eksempler på korrekt kildeangivelse og referencer i henhold til APA referencing system.Vejledning i at undgå plagiering ved at følge de normer, der gælder for good academic practice. Dette indebærer at man angiver kilder korrekt, og...

  17. Apa-Tappi Whole-Tree Utilization Committee: review of achievements

    Energy Technology Data Exchange (ETDEWEB)

    Plummer, G M

    1978-03-01

    The Apa-Tappi Whole-Tree Utilization Committee started its activities in mid-1974 with people who pioneered the concept of whole-tree chipping. The major problem retarding expansion of use of these chips was determined to be grit and dirt, which is primarily associated with bark and foliage. Utilization of research and tests by member companies and communication with manufacturers resulted in commercial applications that improved chip quality. Other achievements have been the establishment of a nationwide project to develop tree-weight tables, documentation of associated problems, harvesting equipment improvements, screening and separation advances, and needed research work.

  18. Manual of References, Creating Tables and Figures in Scholarly Publications: APA 6 Rules

    Directory of Open Access Journals (Sweden)

    Mehmet Ali Akkaya

    2016-12-01

    Full Text Available One precondition of contribution of a discipline to its field, to the scientific word in general and to the entire humankind is producing qualified scientific publications in the related field or discipline. National and international standard(s provided for citing and referencing tables and figures, in addition to the content (and context of the scientific publications might provide the relevant publication to be more widely and correctly read and reviewed. This study deals with adaptation of the latest edition of the American Psychological Association (APA rules. This book, where the APA rules -already a universal authority in citing and referencing- are enriched with specific examples for every type of information source, is a basic reference source after Prof. Dr. S. Kurbanoğlu’s “Kaynak Gösterme El Kitabı” (Referencing Handbook in 2004 that can be implemented not only to the Information and Records Management field, but to the whole scientific world. The meaning and importance of the work of Şencan and Doğan, is much more profound in our country where along with the quality of the scientific publications, the stylistic compatibility with the scientific criteria is also very often questioned.

  19. Sümeyra Tosun: Psi Chi/APA Edwin B. Newman Graduate Research Award.

    Science.gov (United States)

    2014-11-01

    The Edwin B. Newman Graduate Research Award is given jointly by Psi Chi and APA. The award was established to recognize young researchers at the beginning of their professional lives and to commemorate both the 50th anniversary of Psi Chi and the 100th anniversary of psychology as a science (dating from the founding of Wundt's laboratory). The 2014 recipient is Sümeyra Tosun. Tosun was chosen for "an outstanding research paper that examines the cognitive repercussions of obligatory versus optional marking of evidentiality, the linguistic coding of the source of information. In English, evidentiality is conveyed in the lexicon through the use of adverbs. In Turkish, evidentiality is coded in the grammar. In two experiments, it was found that English speakers were equally good at remembering and monitoring the source of firsthand information and the source of non-firsthand information. Turkish speakers were worse at remembering and monitoring non-firsthand information than firsthand information and were worse than English speakers at remembering and monitoring non-firsthand information." Tosun's award citation, biography, and a selected bibliography are presented here. PsycINFO Database Record (c) 2014 APA, all rights reserved.

  20. Linking contemporary research to the classics: Celebrating 125 years at APA.

    Science.gov (United States)

    Enns, James T; Becker, Stefanie I; Brockmole, James; Castelhano, Monica; Creem-Regehr, Sarah; Gray, Rob; Hecht, Heiko; Juhasz, Barbara; Philbeck, John; Woodman, Geoffrey

    2017-10-01

    APA is celebrating 125 years this year and at the journal we are commemorating this milestone with a special issue. The inspiration came from our editorial team, who wished to acknowledge the links between game-changing articles that have influenced our research community in the past-we call them classics for short-and contemporary works. The main idea was to feature the work of nine contemporary research teams, while at the same time drawing readers' attention to their links with the classics. In this introduction, we have organized the articles according to several broad themes: active perception, perception for action, action alters perception, perception of our bodies in action, and acting on selective perceptions. As all who have read and contributed to the journal over the past few years have come to realize, it is no longer possible to study perception without considering its role in action. Nor is it possible to study action (formerly called performance , as reflected in the journal title) without understanding the perceptual contributions to action. These nine articles each exemplify, in their own way, how these dynamic interactions play out in contemporary research in our field. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  1. Journal article reporting standards for quantitative research in psychology: The APA Publications and Communications Board task force report.

    Science.gov (United States)

    Appelbaum, Mark; Cooper, Harris; Kline, Rex B; Mayo-Wilson, Evan; Nezu, Arthur M; Rao, Stephen M

    2018-01-01

    Following a review of extant reporting standards for scientific publication, and reviewing 10 years of experience since publication of the first set of reporting standards by the American Psychological Association (APA; APA Publications and Communications Board Working Group on Journal Article Reporting Standards, 2008), the APA Working Group on Quantitative Research Reporting Standards recommended some modifications to the original standards. Examples of modifications include division of hypotheses, analyses, and conclusions into 3 groupings (primary, secondary, and exploratory) and some changes to the section on meta-analysis. Several new modules are included that report standards for observational studies, clinical trials, longitudinal studies, replication studies, and N-of-1 studies. In addition, standards for analytic methods with unique characteristics and output (structural equation modeling and Bayesian analysis) are included. These proposals were accepted by the Publications and Communications Board of APA and supersede the standards included in the 6th edition of the Publication Manual of the American Psychological Association (APA, 2010). (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  2. Techniques for heating eccentrically located tumors with the BSD annular phased array system (APAS): Clinical experience

    International Nuclear Information System (INIS)

    Samulski, T.V.; Kapp, D.S.; Bagshaw, M.A.; Fessenden, P.; Lee, E.R.; Lohrbach, A.W.

    1985-01-01

    The authors are currently investigating the potential for treatment optimization with the BSD APAS in tumors which are eccentrically located within the lower abdomen and pelvis. Attempts have been made to manipulate electric field (E-field) distribution during treatments through frequency changes and partial array activation (driving less than all four quadrants). Field shifts are qualitatively documented using the manufacturer's supplied diode array probes located at the patient/bolus interface in anterior, posterior and bilateral positions. Preliminary findings indicate that the internal E-field distributions can be manipulated to result in better treatment tolerance and better temperature distributions in selected target volumes. Phantom and clinical data are presented demonstrating the utility of these approaches

  3. APA-style human milk fat analogue from silkworm pupae oil: Enzymatic production and improving storage stability using alkyl caffeates.

    Science.gov (United States)

    Liu, Xi; Wang, Xudong; Pang, Na; Zhu, Weijie; Zhao, Xingyu; Wang, Fangqin; Wu, Fuan; Wang, Jun

    2015-12-08

    Silkworm pupae oil derived from reeling waste is a rich source of α-linolenic acid (ALA), which has multipal applications. ALAs were added in sn-1, 3 positions in a triacylglycerol (TAG) to produce an APA-human milk fat analogues (APA-HMFAs, A: α-linolenic acid, P: palmitic acid). The optimum condition is that tripalmitin to free fatty acids of 1:12 (mole ratio) at 65 °C for 48 h using lipase Lipozyme RM IM. Results show that, the major TAG species that comprised APA-HMFAs were rich in ALA and palmitic acid, which contained 64.52% total unsaturated fatty acids (UFAs) and 97.05% PA at the sn-2 position. The melting point of APA was -27.5 °C which is much lower than tripalmitin (40.5 °C) indicating more plastic character. In addition, the practical application of alkyl caffeates as liposoluble antioxidants in APA was developed. Alkyl caffeate showed a superior IC50 (1.25-1.66 μg/mL) compared to butyl hydroxy anisd (1.67 μg/mL) and L-ascorbic acid-6-palmitate (L-AP) (1.87 μg/mL) in DPPH analysis. The addition of ethyl caffeate to oil achieved a higher UFAs content (73.58%) at high temperatures. Overall, APA was obtained from silkworm pupae oil successfully, and the addition of caffeates extended storage ranges for APA-HMFAs.

  4. Role of the VDR Bsm I and Apa I polymorphisms in the risk of colorectal cancer in Kashmir.

    Science.gov (United States)

    Rasool, Sabha; Kadla, Showkat A; Rasool, Vamiq; Qazi, Falak; Khan, Tanzeela; Shah, Nisar A; Ganai, Bashir A

    2014-01-01

    A case-control study aiming to evaluate the relationship between Bsm I and Apa I restriction fragment gene polymorphisms and colorectal cancer (CRC) was carried out in Kashmir, including a total of 368 subjects (180 cases and 188 controls). DNA samples extracted from the blood of the subjects were analyzed for 3' untranslated region (3' UTR) Apa I and Bsm I polymorphisms using restriction fragment length polymorphism-polymerase chain reaction (RFLP-PCR). A statistically significant 2.7-fold increased risk was observed in individuals found homozygous for the presence of the 'b' allele, in comparison to subjects homozygous for the 'B' allele (odds ratio (OR) 2.7, 95% confidence interval (CI) 1.49-4.86 (Bsm I)), and a statistically insignificant 2-fold increased risk was found among individuals with the 'aa' genotype, as compared to subjects with the 'AA' genotype (OR 2.017, 95% CI 0.86-4.7). Our study also yielded statistically significant results when the Apa I polymorphism was stratified by age (≤ 50 years) and dwelling area (rural area), and the Bsm I polymorphism by gender (male gender), suggesting a possible role of Apa I and Bsm I polymorphisms in the etiology of CRC in Kashmir. We conclude that Apa I and Bsm I single-nucleotide polymorphisms (SNPs) in the vitamin D receptor gene (VDR) might be associated with susceptibility to CRC among Kashmiris. © 2014 S. Karger GmbH, Freiburg.

  5. IL-1RA gene-transfected bone marrow-derived mesenchymal stem cells in APA microcapsules could alleviate rheumatoid arthritis.

    Science.gov (United States)

    Hu, Jianhua; Li, Hongjian; Chi, Guanhao; Yang, Zhao; Zhao, Yi; Liu, Wei; Zhang, Chao

    2015-01-01

    In order to investigate the encapsulation of interleukin 1 receptor antagonist (IL-RA) gene-modified mesenchymal stem cells (MSCs) in alginate-poly-L-lysine (APA) microcapsules for the persistent delivery of interleukin 1 receptor antagonist (IL-RA) to treat Rheumatoid arthritis (RA). We transfect mesenchymal stem cells with IL-RA gene, and quantify the IL-RA proteins released from the encapsulated cells followed by microencapsulation of recombinant mesenchymal stem cells, and thus observe the permeability of APA microcapsules and evaluate clinical effects after induction and treatment of collagen-induced arthritis (CIA). The concentration of IL-RA in the supernatant was determined by IL-RA ELISA kit by run in technical triplicates using samples from three separate mice. Encapsulated IL-RA gene-transfected cells were capable of constitutive delivery of IL-RA proteins for at least 30 days. Moreover, the APA microcapsules could inhibit the permeation of fluorescein isothiocyanate-conjuncted immunoglobulin G. Also, it has been found that the APA microcapsules can significantly attenuate collagen induced arthritis after delivering of APA microcapsules to rats. Our results demonstrated that the nonautologous IL-RA gene-transfected stem cells are of potential utility for RA therapy.

  6. The affection of APA microcapsulation on catecholamine and leucine-enkephalin secretion from the bovine adrenal medullary chromaffin cells

    International Nuclear Information System (INIS)

    Guo Shuilong; Cui Xin; Luo Yun; Xue Yilong

    2002-01-01

    The affection of alginate-polylysine-alginate (APA) microcapsulation on catecholamine (CA) and leucine-enkephalin (L-EK) secretion from bovine adrenal medullary chromaffin cells was analysed. Encapsulating BCCs with the APA microcapsulation, the secretion of CA and L-EK in encapsulated BCCs was detected by high-performance liquid chromatography-electrochemical assay and radioimmunoassay, respectively. There is little difference between the encapsulated BCCs and the non-encapsulated BCCs in the secretion of epinephrine (E) and noradrenaline (NE) but the secretion of dopamine (DA) and L-EK in several points decline. The studies indicated that APA microcapsulation of BCCs didn't affect the secretion of E and NE, but did the secretion DA and L-EK in forepart

  7. Unidades de conservação, Legislação ambiental e a APA Petrópolis

    Directory of Open Access Journals (Sweden)

    Julieta Laudelina de Paiva

    2010-12-01

    Full Text Available As unidades de conservação são criadas com o objetivo de manter a diversidade biológica, proteger espécies ameaçadas de extinção, preservar e restaurar ecossistemas naturais. A Área de Proteção Ambiental da Região Serrana de Petrópolis – APA PETRÓPOLIS, primeira APA federal, foi criada por apresentar rica biodiversidade além de ter seus atributos naturais relativamente bem conservados. A população residente na APA Petrópolis está submetida ao cumprimento de várias determinações legais nos três níveis administrativos.

  8. The Neuro-Mechanical Processes That Underlie Goal-Directed Medio-Lateral APA during Gait Initiation.

    Science.gov (United States)

    Honeine, Jean-Louis; Schieppati, Marco; Crisafulli, Oscar; Do, Manh-Cuong

    2016-01-01

    Gait initiation (GI) involves passing from bipedal to unipedal stance. It requires a rapid movement of the center of foot pressure (CoP) towards the future swing foot and of the center of mass (CoM) in the direction of the stance foot prior to the incoming step. This anticipatory postural adjustment (APA) allows disengaging the swing leg from the ground and establishing favorable conditions for stepping. This study aimed to describe the neuro-mechanical process that underlies the goal-directed medio-lateral (ML) APA. We hypothesized that controlled knee flexion of the stance leg contributes to the initial ML displacement of the CoP and to the calibration of the first step. Fourteen subjects initiated gait starting from three different initial stance widths of 15 cm (Small), 30 cm (Medium), and 45 cm (Large). Optoelectronic, force platform and electromyogram (EMG) measurements were performed. During APA, soleus activity diminished bilaterally, while tibialis anterior (TA) activity increased, more so in the stance leg than in the swing leg, and to a larger extent with increasing initial stance width. Knee flexion of the stance leg was observed during APA and correlated with the ML CoP displacement towards the swing leg. ML CoP and CoM displacements during APA increased with increasing stance width. The activity of stance-leg TA was correlated with the degree of knee flexion. Swing-leg tensor fasciae latae (TFL) was also active during APA. Across subjects, when stance-leg tibialis activity was low, TFL activity was large and vice versa. The modulation of the ML CoP position during APA allowed the gravity-driven torque to place the CoM just lateral to the stance foot during step execution. Accordingly, the gravity-driven torque, the ML CoM velocity during step execution, and the step width at foot contact (FC) were lower in the Small and greater in the Large condition. Consequently, the position of the stepping foot at FC remained close to the sagittal plane in all

  9. The APA Ethical Principles as a foundational competency: application to rehabilitation psychology.

    Science.gov (United States)

    Hanson, Stephanie L; Kerkhoff, Thomas R

    2011-08-01

    Competence is a core component of ethical conduct as reflected in its addition as an ethical standard in the 2002 APA Ethics Code. Successfully operationalizing and assessing competence provides psychologists a means to improve education and training, advance the field of practice, and create a framework for accountability to the public. Much of the recent competency discussion has been in response to a proposed Cube Model, with its three axes being foundational competencies (practice building blocks, such as scientific knowledge, ethical standards), functional competencies (attributes of providing services, such as assessment, intervention), and developmental progression (acquiring increasing competence over the course of one's education and career). Ethics is included on the foundational competency axis and has been operationalized to the extent that subcomponents and benchmarks have been promulgated. The competency model as proposed faces multiple challenges, including gaining consensus regarding its components, addressing reliable and valid assessment over time, and creating a culture of acceptance. We propose the Ethical Principles as an alternative framework for conceptualizing ethics as a foundational competency given the Ethics Code is already time tested and includes a serial review process for broad discipline input and adaptability. We apply the Ethical Principles as foundational components to rehabilitation psychology training at internship, postdoctoral, and specialty levels to illustrate the model. Rehabilitation psychology should engage in the competency movement at the predoctoral and postdoctoral level. The application of the Ethical Principles as a foundational competency to rehabilitation psychology represents a first step in this dialog.

  10. The urban-rural dichotomy in the Indonesian documentaries Nona nyonya? and Untuk apa?

    Directory of Open Access Journals (Sweden)

    Asri Saraswati

    2012-04-01

    Full Text Available The media play a pivotal role in the democratization process in Indonesia and this is among others apparent in the surge of films, both fiction and documentaries that have been produced after the end Suharto’s decades of control over the media. It is important to note, however, that compared with fiction films, the documentary genre remains rather unpopular in Indonesia. Indonesian documentary films struggle to depict stories of the subaltern and those living in the “periphery” in order for them to be seen and heard by the greater masses and by those in power – the ones in the “centre” or Jakarta. This paper discusses the connection between urban and rural voices and its impact in the documentary films Nona nyonya? (Miss mrs?, 2008 and Untuk apa? (What’s the point?, 2008 produced by Kalyana Shira Films, an organization well-known for its work on gender issues using film as medium. Departing from the notion that the film industry itself is still largely Jakarta-centred, this article focuses on the way urban settings and voices are used to create rhetoric, and the impact of the domination of these urban voices over the rural ones.

  11. Synthesis and properties of ApA analogues with shortened phosphonate internucleotide linkage.

    Science.gov (United States)

    Králíková, Sárka; Buděšínský, Miloš; Barvík, Ivan; Masojídková, Milena; Točík, Zdeněk; Rosenberg, Ivan

    2011-01-01

    A complete series of the 2 '-5 ' and 3 '-5 ' regioisomeric types of r(ApA) and 2 '-d(ApA) analogues with the α-hydroxy-phosphonate C3 '-O-P-CH(OH)-C4 ″ internucleotide linkage, isopolar but non-isosteric with the phosphodiester one, were synthesized and their hybridization properties with polyU studied. Due to the chirality on the 5 '-carbon atom of the modified internucleotide linkage bearing phosphorus and hydroxy moieties, each regioisomeric type of ApA dimer is split into epimeric pairs. To examine the role of the 5 '-hydroxyl of the α-hydroxy-phosphonate moiety during hybridization, the appropriate r(ApA) analogues with 3 '(2 ')-O-P-CH(2)-C4 ″ linkage lacking the 5 '-hydroxyl were synthesized. Nuclear magnetic resonance (NMR) spectroscopy study on the conformation of the modified sugar-phosphate backbone, along with the hybridization measurements, revealed remarkable differences in the stability of complexes with polyU, depending on the 5 '-carbon atom configuration. Potential usefulness of the α-hydroxy-phosphonate linkage in modified oligoribonucleotides is discussed.

  12. Article Publications, Journal Outlets, and Article Themes for Current Faculty in APA-Accredited School Psychology Programs: 1995?1999

    Science.gov (United States)

    Carper, Robin M.; Williams, Robert L.

    2004-01-01

    The study addressed three major questions regarding the 1995?1999 journal publications of faculty at school psychology programs accredited by the American Psychological Association (APA) as of Sept. 1, 2000: (a) Which program faculties had the strongest records of article publications for 1995?1999? (b) What were the major school psychology and…

  13. A Reliable and Valid Weighted Scoring Instrument for Use in Grading APA-Style Empirical Research Report

    Science.gov (United States)

    Greenberg, Kathleen Puglisi

    2012-01-01

    The scoring instrument described in this article is based on a deconstruction of the seven sections of an American Psychological Association (APA)-style empirical research report into a set of learning outcomes divided into content-, expression-, and format-related categories. A double-weighting scheme used to score the report yields a final grade…

  14. Advocating for School Psychologists in Response to the APA's Proposed "Model Act for State Licensure of Psychologists"

    Science.gov (United States)

    Skalski, Anastasia Kalamaros

    2009-01-01

    On March 6, 2009, the APA Model Licensure Act Task Force released its second draft of the policy document known as the proposed "Model Act for State Licensure of Psychologists". This policy document serves as guidance to state legislatures for how they should set up their psychology licensing laws. The general expectations promoted in the model…

  15. APA guidelines: their importance and a plan to keep them current: 2013 annual report of the Policy and Planning Board.

    Science.gov (United States)

    2014-01-01

    When guidelines are approved by APA, they become association policy, and it is imperative that they remain current. The revision of guidelines poses several challenges to the association. These challenges range from the availability and allocation of resources to support the complicated processes involved in developing and updating these policies to the lack of a clearly defined process that includes identification of tasks, assignments of responsibilities, and so forth. For this reason, the APA Board of Directors asked the Policy and Planning Board (P&P) to work with the boards of the four directorates (i.e., the Education Directorate, the Practice Directorate, the Public Interest Directorate, and the Science Directorate) to create a proposal that would (a) make recommendations with regard to how the review and revision of guidelines documents might best be accomplished in accordance with the APA Strategic Plan and existing policies and procedures and (b) make suggestions regarding the association resources that might be required. The Board of Directors approved the proposed review process in December 2013. 2014 APA, all rights reserved

  16. Association of Taq I, Fok I and Apa I polymorphisms in Vitamin D Receptor (VDR) gene with leprosy.

    Science.gov (United States)

    Neela, Venkata Sanjeev Kumar; Suryadevara, Naveen Chandra; Shinde, Vidya Gouri; Pydi, Satya Sudheer; Jain, Suman; Jonnalagada, Subbanna; Singh, Surya Satyanarayana; Valluri, Vijaya Lakshmi; Anandaraj, M P J S

    2015-06-01

    Vitamin D Receptor (VDR) is a transacting transcription factor which mediates immunomodulatory function and plays a key role in innate and adaptive immune responses through its ligand and polymorphisms in VDR gene may affect its regulatory function. To investigate the association of three VDR gene polymorphisms (TaqI rs731236, FokI rs2228570 and ApaI rs7975232) with leprosy. The study group includes 404 participants of which 222 were leprosy patients (paucibacillary=87, multibacillary=135) and 182 healthy controls. Genotyping was done using PCR-RFLP technique. Statistical analysis was performed using SNP Stats and PLINK software. The VDR FokI (rs2228570) ff genotype, ApaI (rs7975232) AA, Aa genotype and haplotype T-f-a, T-F-A were positively associated with leprosy when compared to healthy controls. The two variants at Fok and Apa positions in VDR gene are significantly associated with leprosy. Genotypes at FokI (ff), ApaI (aa) and haplotype (T-F-a, T-f-a) may contribute to the risk of developing leprosy by altering VDR phenotype/levels subsequently modulation of immune response. Copyright © 2015 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.

  17. Changes in the APA "Publication Manual": How the New Fifth Edition Will Affect Research Reporting in the Social Sciences.

    Science.gov (United States)

    Daniel, Larry G.

    The American Psychological Association (APA) has recently published the fifth edition of its "Publication Manual." This paper provides a brief overview of how this edition differs from previous editions and summarizes features of the new edition that will be likely to have an impact on social science research over the next several years.…

  18. PLANEJAMENTO DE UMA TRILHA INTERPRETATIVA COMO FERRAMENTA DO ECOTURISMO NA APA DA BARRA DO RIO MAMANGUAPE - PARAÍBA, BRASIL

    Directory of Open Access Journals (Sweden)

    Mércia Maria Araújo Luna

    2016-04-01

    Full Text Available A Floresta Atlântica é um bioma biodiverso e extremamente impactado. A Área de Proteção Ambiental (APA da Barra do Rio Mamanguape encontra-se inserida no hotspot da Floresta Atlântica. Este trabalho visa propor a implantação de uma trilha interpretativa na APA com base no Ecoturismo e na Educação Ambiental. Durante o mês de abril e maio de 2014 foi elaborado um roteiro mapeando os pontos estratégicos da trilha, elencando seus elementos mais representativos e registrando-os ao longo de 3.8 Km. Várias características da trilha foram consideradas na elaboração deste planejamento: a proteção do ambiente da trilha, seu potencial interpretativo, a acessibilidade e segurança. Os resultados apontaram nove pontos de atratividade onde foram abordados aspectos de relevância da flora, da fauna e da história da APA. Nota-se a necessidade da implantação de trilhas ecológicas no principal e maior fragmento de Floresta Atântica da APA, a Floresta do Oiteiro, uma vez que as trilhas só estão previstas no plano de manejo para um dos quatro municípios que abrange a APA, Lucena. Destaque pode ser dado à necessidade de treinamento de uma equipe local da Unidade de Conservação (UC para manter vivo o instrumento da trilha interpretativa, associando a interlocução entre a comunidade acadêmica da UFPB e os turistas pelo seu caráter amplo e interdisciplinar. Palavras-chave: Floresta Atlântica. Unidades de conservação. Turismo ecológico.

  19. Selling violent video game solutions: A look inside the APA's internal notes leading to the creation of the APA's 2005 resolution on violence in video games and interactive media.

    Science.gov (United States)

    Copenhaver, Allen; Ferguson, Christopher J

    For decades politicians, parent groups, researchers, media outlets, professionals in various fields, and laymen have debated the effects playing violent video games have on children and adolescents. In academia, there also exists a divide as to whether violent video games cause children and adolescents to be aggressive, violent, and even engage in criminal behavior. Given inconsistencies in the data, it may be important to understand the ways and the reasons why professional organizations take a stance on the violent video game effects debate which may reflect greater expressed certitude than data can support. This piece focuses on the American Psychological Association's internal communications leading to the creation of their 2005 Resolution on Violence in Video Games and Interactive Media. These communications reveal that in this case, the APA attempted to "sell" itself as a solution to the perceived violent video game problem. The actions leading to the 2005 resolution are then compared to the actions of the APA's 2013-2015 Task Force on Violent Media. The implications and problems associated with the APA's actions regarding violent video games are addressed and discussed below. Copyright © 2018 Elsevier Ltd. All rights reserved.

  20. Characterization of the Apa antigen from M. avium subsp. paratuberculosis: a conserved Mycobacterium antigen that elicits a strong humoral response in cattle.

    Science.gov (United States)

    Gioffré, A; Echeverría-Valencia, G; Arese, A; Morsella, C; Garbaccio, S; Delgado, F; Zumárraga, M; Paolicchi, F; Cataldi, A; Romano, M I

    2009-12-15

    Johne's disease or paratuberculosis is widespread in almost all countries and remains difficult to eradicate. Nowadays, diagnosis of Mycobacterium avium subsp. paratuberculosis (MPTB) infection is one of the main concerns. In this work, we evaluated the expression, biochemical properties and antigenicity of the Apa antigen, encoded by the gene annotated as MAP1569, in the MPTB genome. We confirmed its expression in MPTB and its glycosylation by the ConA binding assay. Although the MPTB-Apa is not an immunodominant antigen, MPTB-infected cattle showed a strong humoral response to recombinant Apa by Western blot and ELISA. Milk was also a suitable sample to be tested by ELISA. We comparatively analysed the humoral cross-reactivity to the Apa from MPTB (MPTB-Apa) and the orthologue from Mycobacterium tuberculosis (MT-Apa, identical to that from Mycobacterium bovis) in both infected and control cows. Response of M. bovis- and MPTB-infected animals against MT-Apa was similar (P=0.6985) but the response of the M. bovis-infected ones to MPTB-Apa was differential, being significantly diminished (PApa stimulation in the IFNgamma release assay, we found no significant differences when compared infected herds with non-infected ones (P=0.34). This antigen, in contrast to bovine Purified Protein Derivative (PPDb), was strongly represented in avian PPD (PPDa), as shown by the recognition of BALB/c mice hyperimmune sera against MPTB-Apa by Dot-blot immunoassay. We therefore demonstrated the antigenicity of Apa in MPTB-infected animals and a differential response to the recombinant antigen when compared to M. bovis-infected animals. These traits herein described, added to the usefulness of milk samples to detect IgG anti-Apa, could be important for routine screening in dairy cattle, considering a multiantigenic approach to overcome the lack of immunodominance.

  1. The science of ethics: Deception, the resilient self, and the APA code of ethics, 1966-1973.

    Science.gov (United States)

    Stark, Laura

    2010-01-01

    This paper has two aims. The first is to shed light on a remarkable archival source, namely survey responses from thousands of American psychologists during the 1960s in which they described their contemporary research practices and discussed whether the practices were "ethical." The second aim is to examine the process through which the American Psychological Association (APA) used these survey responses to create principles on how psychologists should treat human subjects. The paper focuses on debates over whether "deception" research was acceptable. It documents how members of the committee that wrote the principles refereed what was, in fact, a disagreement between two contemporary research orientations. The paper argues that the ethics committee ultimately built the model of "the resilient self" into the APA's 1973 ethics code. At the broadest level, the paper explores how prevailing understandings of human nature are written into seemingly universal and timeless codes of ethics. © 2010 Wiley Periodicals, Inc.

  2. "Bad girls rule": an interdisciplinary feminist commentary on the report of the APA Task Force on the Sexualization of Girls.

    Science.gov (United States)

    Lerum, Kari; Dworkin, Shari L

    2009-01-01

    Feminist, critical, and postmodern scholars have long recognized sexuality as a site of power relations. The recently released Report of the APA (American Psychological Association) Task Force on the Sexualization of Girls is a welcome addition to ongoing feminist and activist conversations on how to intervene on issues of sexuality in the name of girls' and women's health. This article offers a critical interdisciplinary analysis of this influential APA report, expanding on and challenging several of its main claims. This article critiques the report as over-determining the negative impact of sexualization; offers other literatures as critical additions including feminist literature on media, consumer culture, gender, and the body, and earlier "pro-desire" feminist psychology scholarship; and critiques the task force's conflations of objectification and sexualization. The article concludes with a call for broadening feminist scholarship and activism across disciplinary boundaries to emphasize girls' and women's sexual agency and resistance, as well as sexual health and rights.

  3. A Proposal for Six Sigma Integration for Large-Scale Production of Penicillin G and Subsequent Conversion to 6-APA

    Directory of Open Access Journals (Sweden)

    Anirban Nandi

    2014-01-01

    Full Text Available Six Sigma methodology has been successfully applied to daily operations by several leading global private firms including GE and Motorola, to leverage their net profits. Comparatively, limited studies have been conducted to find out whether this highly successful methodology can be applied to research and development (R&D. In the current study, we have reviewed and proposed a process for a probable integration of Six Sigma methodology to large-scale production of Penicillin G and its subsequent conversion to 6-aminopenicillanic acid (6-APA. It is anticipated that the important aspects of quality control and quality assurance will highly benefit from the integration of Six Sigma methodology in mass production of Penicillin G and/or its conversion to 6-APA.

  4. A Proposal for Six Sigma Integration for Large-Scale Production of Penicillin G and Subsequent Conversion to 6-APA.

    Science.gov (United States)

    Nandi, Anirban; Pan, Sharadwata; Potumarthi, Ravichandra; Danquah, Michael K; Sarethy, Indira P

    2014-01-01

    Six Sigma methodology has been successfully applied to daily operations by several leading global private firms including GE and Motorola, to leverage their net profits. Comparatively, limited studies have been conducted to find out whether this highly successful methodology can be applied to research and development (R&D). In the current study, we have reviewed and proposed a process for a probable integration of Six Sigma methodology to large-scale production of Penicillin G and its subsequent conversion to 6-aminopenicillanic acid (6-APA). It is anticipated that the important aspects of quality control and quality assurance will highly benefit from the integration of Six Sigma methodology in mass production of Penicillin G and/or its conversion to 6-APA.

  5. Probiotic Ferulic Acid Esterase Active Lactobacillus fermentum NCIMB 5221 APA Microcapsules for Oral Delivery: Preparation and in Vitro Characterization

    OpenAIRE

    Tomaro-Duchesneau, Catherine; Saha, Shyamali; Malhotra, Meenakshi; Coussa-Charley, Michael; Kahouli, Imen; Jones, Mitchell L.; Labb?, Alain; Prakash, Satya

    2012-01-01

    Probiotics possess potential therapeutic and preventative effects for various diseases and metabolic disorders. One important limitation for the oral delivery of probiotics is the harsh conditions of the upper gastrointestinal tract (GIT) which challenge bacterial viability and activity. One proposed method to surpass this obstacle is the use of microencapsulation to improve the delivery of bacterial cells to the lower GIT. The aim of this study is to use alginate-poly-L-lysine-alginate (APA)...

  6. Race, Ethnicity, and Gender of Faculty Members in APA- and CACREP-Accredited Programs: Changes over Five Decades

    Science.gov (United States)

    Baggerly, Jennifer; Tan, Tony Xing; Pichotta, David; Warner, Aisha

    2017-01-01

    This study examined changes in race, ethnicity, and gender of faculty members in APA- and CACREP-accredited counseling programs over 5 decades based on the year of their degree. Of those faculty members working in accredited programs who graduated in the 1960s/1970s, 26.7% were female, 5.6% were racially diverse, and 1.7% were Latina/o. Of those…

  7. Are Adolescents Less Mature than Adults?: Minors' Access to Abortion, the Juvenile Death Penalty, and the Alleged APA "Flip-Flop"

    Science.gov (United States)

    Steinberg, Laurence; Cauffman, Elizabeth; Woolard, Jennifer; Graham, Sandra; Banich, Marie

    2009-01-01

    The American Psychological Association's (APA's) stance on the psychological maturity of adolescents has been criticized as inconsistent. In its Supreme Court amicus brief in "Roper v. Simmons" (2005), which abolished the juvenile death penalty, APA described adolescents as developmentally immature. In its amicus brief in "Hodgson v. Minnesota"…

  8. Putative alternative polyadenylation (APA) events in the early interaction of Salmonella enterica Typhimurium and human host cells.

    Science.gov (United States)

    Afonso-Grunz, Fabian

    2015-12-01

    The immune response of epithelial cells upon infection is mediated by changing activity levels of a variety of proteins along with changes in mRNA, and also ncRNA abundance. Alternative polyadenylation (APA) represents a mechanism that diversifies gene expression similar to alternative splicing. T-cell activation, neuronal activity, development and several human diseases including viral infections involve APA, but at present it remains unclear if this mechanism is also implicated in the response to bacterial infections. Our recently published study of interacting Salmonella enterica Typhimurium and human host cells includes genome-wide expression profiles of human epithelial cells prior and subsequent to infection with the invasive pathogen. The generated dataset (GEO accession number: GSE61730) covers several points of time post infection, and one of these interaction stages was additionally profiled with MACE-based dual 3'Seq, which allows for identification of polyadenylation (PA) sites. The present study features the polyadenylation landscape in early interacting cells based on this data, and provides a comparison of the identified PA sites with those of a corresponding 3P-Seq dataset of non-interacting cells. Differential PA site usage of FTL , PRDX1 and VAPA results in transcription of mRNA isoforms with distinct sets of miRNA and protein binding sites that influence processing, localization, stability, and translation of the respective mRNA. APA of these candidate genes consequently harbors the potential to modulate the host cell response to bacterial infection.

  9. Putative alternative polyadenylation (APA events in the early interaction of Salmonella enterica Typhimurium and human host cells

    Directory of Open Access Journals (Sweden)

    Fabian Afonso-Grunz

    2015-12-01

    Full Text Available The immune response of epithelial cells upon infection is mediated by changing activity levels of a variety of proteins along with changes in mRNA, and also ncRNA abundance. Alternative polyadenylation (APA represents a mechanism that diversifies gene expression similar to alternative splicing. T-cell activation, neuronal activity, development and several human diseases including viral infections involve APA, but at present it remains unclear if this mechanism is also implicated in the response to bacterial infections. Our recently published study of interacting Salmonella enterica Typhimurium and human host cells includes genome-wide expression profiles of human epithelial cells prior and subsequent to infection with the invasive pathogen. The generated dataset (GEO accession number: GSE61730 covers several points of time post infection, and one of these interaction stages was additionally profiled with MACE-based dual 3'Seq, which allows for identification of polyadenylation (PA sites. The present study features the polyadenylation landscape in early interacting cells based on this data, and provides a comparison of the identified PA sites with those of a corresponding 3P-Seq dataset of non-interacting cells. Differential PA site usage of FTL, PRDX1 and VAPA results in transcription of mRNA isoforms with distinct sets of miRNA and protein binding sites that influence processing, localization, stability, and translation of the respective mRNA. APA of these candidate genes consequently harbors the potential to modulate the host cell response to bacterial infection.

  10. Probiotic Ferulic Acid Esterase Active Lactobacillus fermentum NCIMB 5221 APA Microcapsules for Oral Delivery: Preparation and in Vitro Characterization

    Directory of Open Access Journals (Sweden)

    Catherine Tomaro-Duchesneau

    2012-02-01

    Full Text Available Probiotics possess potential therapeutic and preventative effects for various diseases and metabolic disorders. One important limitation for the oral delivery of probiotics is the harsh conditions of the upper gastrointestinal tract (GIT which challenge bacterial viability and activity. One proposed method to surpass this obstacle is the use of microencapsulation to improve the delivery of bacterial cells to the lower GIT. The aim of this study is to use alginate-poly-L-lysine-alginate (APA microcapsules to encapsulate Lactobacillus fermentum NCIMB 5221 and characterize its enzymatic activity and viability through a simulated GIT. This specific strain, in previous research, was characterized for its inherent ferulic acid esterase (FAE activity which could prove beneficial in the development of a therapeutic for the treatment and prevention of cancers and metabolic disorders. Our findings demonstrate that the APA microcapsule does not slow the mass transfer of substrate into and that of the FA product out of the microcapsule, while also not impairing bacterial cell viability. The use of simulated gastrointestinal conditions led to a significant 2.5 log difference in viability between the free (1.10 × 104 ± 1.00 × 103 cfu/mL and the microencapsulated (5.50 × 106 ± 1.00 × 105 cfu/mL L. fermentum NCIMB 5221 following exposure. The work presented here suggests that APA microencapsulation can be used as an effective oral delivery method for L. fermentum NCIMB 5221, a FAE-active probiotic strain.

  11. Probiotic Ferulic Acid Esterase Active Lactobacillus fermentum NCIMB 5221 APA Microcapsules for Oral Delivery: Preparation and in Vitro Characterization

    Science.gov (United States)

    Tomaro-Duchesneau, Catherine; Saha, Shyamali; Malhotra, Meenakshi; Coussa-Charley, Michael; Kahouli, Imen; Jones, Mitchell L.; Labbé, Alain; Prakash, Satya

    2012-01-01

    Probiotics possess potential therapeutic and preventative effects for various diseases and metabolic disorders. One important limitation for the oral delivery of probiotics is the harsh conditions of the upper gastrointestinal tract (GIT) which challenge bacterial viability and activity. One proposed method to surpass this obstacle is the use of microencapsulation to improve the delivery of bacterial cells to the lower GIT. The aim of this study is to use alginate-poly-L-lysine-alginate (APA) microcapsules to encapsulate Lactobacillus fermentum NCIMB 5221 and characterize its enzymatic activity and viability through a simulated GIT. This specific strain, in previous research, was characterized for its inherent ferulic acid esterase (FAE) activity which could prove beneficial in the development of a therapeutic for the treatment and prevention of cancers and metabolic disorders. Our findings demonstrate that the APA microcapsule does not slow the mass transfer of substrate into and that of the FA product out of the microcapsule, while also not impairing bacterial cell viability. The use of simulated gastrointestinal conditions led to a significant 2.5 log difference in viability between the free (1.10 × 104 ± 1.00 × 103 cfu/mL) and the microencapsulated (5.50 × 106 ± 1.00 × 105 cfu/mL) L. fermentum NCIMB 5221 following exposure. The work presented here suggests that APA microencapsulation can be used as an effective oral delivery method for L. fermentum NCIMB 5221, a FAE-active probiotic strain. PMID:24288090

  12. Probiotic Ferulic Acid Esterase Active Lactobacillus fermentum NCIMB 5221 APA Microcapsules for Oral Delivery: Preparation and in Vitro Characterization.

    Science.gov (United States)

    Tomaro-Duchesneau, Catherine; Saha, Shyamali; Malhotra, Meenakshi; Coussa-Charley, Michael; Kahouli, Imen; Jones, Mitchell L; Labbé, Alain; Prakash, Satya

    2012-02-16

    Probiotics possess potential therapeutic and preventative effects for various diseases and metabolic disorders. One important limitation for the oral delivery of probiotics is the harsh conditions of the upper gastrointestinal tract (GIT) which challenge bacterial viability and activity. One proposed method to surpass this obstacle is the use of microencapsulation to improve the delivery of bacterial cells to the lower GIT. The aim of this study is to use alginate-poly-L-lysine-alginate (APA) microcapsules to encapsulate Lactobacillus fermentum NCIMB 5221 and characterize its enzymatic activity and viability through a simulated GIT. This specific strain, in previous research, was characterized for its inherent ferulic acid esterase (FAE) activity which could prove beneficial in the development of a therapeutic for the treatment and prevention of cancers and metabolic disorders. Our findings demonstrate that the APA microcapsule does not slow the mass transfer of substrate into and that of the FA product out of the microcapsule, while also not impairing bacterial cell viability. The use of simulated gastrointestinal conditions led to a significant 2.5 log difference in viability between the free (1.10 × 104 ± 1.00 × 103 cfu/mL) and the microencapsulated (5.50 × 106 ± 1.00 × 105 cfu/mL) L. fermentum NCIMB 5221 following exposure. The work presented here suggests that APA microencapsulation can be used as an effective oral delivery method for L. fermentum NCIMB 5221, a FAE-active probiotic strain.

  13. Errors in the 2017 APA Clinical Practice Guideline for the Treatment of PTSD: What the Data Actually Says

    Directory of Open Access Journals (Sweden)

    Sarah K. Dominguez

    2017-08-01

    Full Text Available The American Psychological Association (APA Practice Guidelines for the Treatment of Posttraumatic Stress Disorder (PTSD concluded that there was strong evidence for cognitive behavioral therapy (CBT, cognitive processing therapy (CPT, cognitive therapy (CT, and exposure therapy yet weak evidence for eye movement desensitization and reprocessing (EMDR. This is despite the findings from an associated systematic review which concluded that EMDR leads to loss of PTSD diagnosis and symptom reduction. Depression symptoms were also found to improve more with EMDR than control conditions. In that review, EMDR was marked down on strength of evidence (SOE for symptom reduction for PTSD. However, there were several problems with the conclusions of that review. Firstly, in assessing the evidence in one of the studies, the reviewers chose an incorrect measure that skewed the data. We recalculated a meta-analysis with a more appropriate measure and found the SOE improved. The resulting effect size for EMDR on PTSD symptom reduction compared to a control condition was large for studies that meet the APA inclusion criteria (SMD = 1.28 and the heterogeneity was low (I2= 43%. Secondly, even if the original measure was chosen, we highlight inconsistencies with the way SOE was assessed for EMDR, CT, and CPT. Thirdly, we highlight two papers that were omitted from the analysis. One of these was omitted without any apparent reason. It found EMDR superior to a placebo control. The other study was published in 2015 and should have been part of APA guidelines since they were published in 2017. The inclusion of either study would have resulted in an improvement in SOE. Including both studies results in standard mean difference and confidence intervals that were better for EMDR than for CPT or CT. Therefore, the SOE should have been rated as moderate and EMDR assessed as at least equivalent to these CBT approaches in the APA guidelines. This would bring the APA

  14. Errors in the 2017 APA Clinical Practice Guideline for the Treatment of PTSD: What the Data Actually Says.

    Science.gov (United States)

    Dominguez, Sarah K; Lee, Christopher W

    2017-01-01

    The American Psychological Association (APA) Practice Guidelines for the Treatment of Posttraumatic Stress Disorder (PTSD) concluded that there was strong evidence for cognitive behavioral therapy (CBT), cognitive processing therapy (CPT), cognitive therapy (CT), and exposure therapy yet weak evidence for eye movement desensitization and reprocessing (EMDR). This is despite the findings from an associated systematic review which concluded that EMDR leads to loss of PTSD diagnosis and symptom reduction. Depression symptoms were also found to improve more with EMDR than control conditions. In that review, EMDR was marked down on strength of evidence (SOE) for symptom reduction for PTSD. However, there were several problems with the conclusions of that review. Firstly, in assessing the evidence in one of the studies, the reviewers chose an incorrect measure that skewed the data. We recalculated a meta-analysis with a more appropriate measure and found the SOE improved. The resulting effect size for EMDR on PTSD symptom reduction compared to a control condition was large for studies that meet the APA inclusion criteria (SMD = 1.28) and the heterogeneity was low ( I 2 = 43%). Secondly, even if the original measure was chosen, we highlight inconsistencies with the way SOE was assessed for EMDR, CT, and CPT. Thirdly, we highlight two papers that were omitted from the analysis. One of these was omitted without any apparent reason. It found EMDR superior to a placebo control. The other study was published in 2015 and should have been part of APA guidelines since they were published in 2017. The inclusion of either study would have resulted in an improvement in SOE. Including both studies results in standard mean difference and confidence intervals that were better for EMDR than for CPT or CT. Therefore, the SOE should have been rated as moderate and EMDR assessed as at least equivalent to these CBT approaches in the APA guidelines. This would bring the APA guidelines in

  15. 我が国の事前確認(APA)の現状と課題 : 事前確認(APA)における納税者のジレンマ <研究ノート>

    OpenAIRE

    虫明, 千春; 佐伯, 健司

    2012-01-01

    移転価格税制の適用に係る問題に対しては,「移転価格事務運営要領」および「事前確認の状況─ APA レポート─」から確認できるとおり,事前確認制度による解決が図られており,特にバイラテラルAPA およびマルチラテラルAPA の利用が強く推奨されている。本研究ノートは,事前確認制度の意義を概観したうえで,納税者の立場から事前確認の利用におけるジレンマを指摘するものである。Givati(2009)の見解における事前確認を利用することによる懸念が,納税者におけるジレンマの一要因となっているものと考える。そのうえで,我が国の事前確認制度の法令による制度化を提言するものである。...

  16. “Citation Style Language” Uygulaması: APA Kaynak Gösterme Biçiminin Türkçeye Adaptasyonu=“Citation Style Language” Application: The Adaptation of APA Style to Turkish Language

    Directory of Open Access Journals (Sweden)

    Kasım Binici

    2013-10-01

    Full Text Available Bibliyografya yönetim programları, araştırma metinlerin yazımında yazarlara büyük avantajlar sağlamaktadır.Akademik çevrede EndNote, RefWorks, Zotero, Mendeley en popüler yazılımlardır. Türkçe kaynak gösterme kurallarının tanımlı olduğu biçim dosyalarının olmaması nedeniyle araştırma metni yazımında bu programlar işlevsiz kalmaktadır. Bu çalışmada, APA kaynak gösterme biçiminin Türkçeye adaptasyonu sağlanarak CSL uygulaması ile biçim dosyasında kodlar yazılmıştır. Yeni biçim dosyası Zotero ve Mendeley programlarında çalışabilirliği test edilerek kişilerin kullanımına sunulmuştur. Çalışma neticesinde oluşturulan APA-TR dosyası sayesinde Türkçe araştırma metinlerinin yazımında CSL uygulamasını tercih eden bibli- yografya yönetim yazılımların kullanımı mümkün olmuştur./Bibliography managment tools provide great advantage for researchers with writing their articles or research papers. In academic environment, EndNote, RefWorks, Zotero, Mendeley are the most popular software programms. Due to the lack of style files in which citation rules in Turkish language are described,these softwares stay functionless. In this study by providing turkish adaptation of APA citation style, new codes were written into the style file via CSL application. New style file is presented to users after testing its workability in Zotero and Mendeley programms. Thanks to APA-TR style file created as a result of the study,it is possibble to use bibliography managment tools which prefer CSL application in writing research papers Turkish language.

  17. Boosting BCG-primed responses with a subunit Apa vaccine during the waning phase improves immunity and imparts protection against Mycobacterium tuberculosis.

    Science.gov (United States)

    Nandakumar, Subhadra; Kannanganat, Sunil; Dobos, Karen M; Lucas, Megan; Spencer, John S; Amara, Rama Rao; Plikaytis, Bonnie B; Posey, James E; Sable, Suraj B

    2016-05-13

    Heterologous prime-boosting has emerged as a powerful vaccination approach against tuberculosis. However, optimal timing to boost BCG-immunity using subunit vaccines remains unclear in clinical trials. Here, we followed the adhesin Apa-specific T-cell responses in BCG-primed mice and investigated its BCG-booster potential. The Apa-specific T-cell response peaked 32-52 weeks after parenteral or mucosal BCG-priming but waned significantly by 78 weeks. A subunit-Apa-boost during the contraction-phase of BCG-response had a greater effect on the magnitude and functional quality of specific cellular and humoral responses compared to a boost at the peak of BCG-response. The cellular response increased following mucosal BCG-prime-Apa-subunit-boost strategy compared to Apa-subunit-prime-BCG-boost approach. However, parenteral BCG-prime-Apa-subunit-boost by a homologous route was the most effective strategy in-terms of enhancing specific T-cell responses during waning in the lung and spleen. Two Apa-boosters markedly improved waning BCG-immunity and significantly reduced Mycobacterium tuberculosis burdens post-challenge. Our results highlight the challenges of optimization of prime-boost regimens in mice where BCG drives persistent immune-activation and suggest that boosting with a heterologous vaccine may be ideal once the specific persisting effector responses are contracted. Our results have important implications for design of prime-boost regimens against tuberculosis in humans.

  18. Vitamin D receptor gene Alw I, Fok I, Apa I, and Taq I polymorphisms in patients with urinary stone.

    Science.gov (United States)

    Seo, Ill Young; Kang, In-Hong; Chae, Soo-Cheon; Park, Seung Chol; Lee, Young-Jin; Yang, Yun Sik; Ryu, Soo Bang; Rim, Joung Sik

    2010-04-01

    To evaluate vitamin D receptor (VDR) gene polymorphisms in Korean patients so as to identify the candidate genes associated with urinary stones. Urinary stones are a multifactorial disease that includes various genetic factors. A normal control group of 535 healthy subjects and 278 patients with urinary stones was evaluated. Of 125 patients who presented stone samples, 102 had calcium stones on chemical analysis. The VDR gene Alw I, Fok I, Apa I, and Taq I polymorphisms were evaluated using the polymerase chain reaction-restriction fragment length polymorphism analysis. Allelic and genotypic frequencies were calculated to identify associations in both groups. The haplotype frequencies of the VDR gene polymorphisms for multiple loci were also determined. For the VDR gene Alw I, Fok I, Apa I, and Taq I polymorphisms, there was no statistically significant difference between the patients with urinary stones and the healthy controls. There was also no statistically significant difference between the patients with calcium stones and the healthy controls. A novel haplotype (Ht 4; CTTT) was identified in 13.5% of the patients with urinary stones and in 8.3% of the controls (P = .001). The haplotype frequencies were significantly different between the patients with calcium stones and the controls (P = .004). The VDR gene Alw I, Fok I, Apa I, and Taq I polymorphisms does not seem to be candidate genetic markers for urinary stones in Korean patients. However, 1 novel haplotype of the VDR gene polymorphisms for multiple loci might be a candidate genetic marker. Copyright 2010 Elsevier Inc. All rights reserved.

  19. Pautas para citar textos y hacer listas de referencias según las normas de la American Psichological Association (APA)

    OpenAIRE

    Ossa, Marcela

    2003-01-01

    La escritura de documentos, artículos, ensayos etc. implica seguir cuidadosamente algunas normas. La Revista EMA se guía para la edición de sus artículos por las normas de la American Psychological Association (APA). El presente documento tiene como objeto dar a conocer algunas de estas normas de tal modo que quien envíe un artículo para su publicación las utilice. Encontrarán algunas pautas para citar textos y hacer listas de referencias según las normas de la American Psychological Associat...

  20. The ApaH-like phosphatase TbALPH1 is the major mRNA decapping enzyme of trypanosomes.

    Directory of Open Access Journals (Sweden)

    Susanne Kramer

    2017-06-01

    Full Text Available 5'-3' decay is the major mRNA decay pathway in many eukaryotes, including trypanosomes. After deadenylation, mRNAs are decapped by the nudix hydrolase DCP2 of the decapping complex and finally degraded by the 5'-3' exoribonuclease. Uniquely, trypanosomes lack homologues to all subunits of the decapping complex, while deadenylation and 5'-3' degradation are conserved. Here, I show that the parasites use an ApaH-like phosphatase (ALPH1 as their major mRNA decapping enzyme. The protein was recently identified as a novel trypanosome stress granule protein and as involved in mRNA binding. A fraction of ALPH1 co-localises exclusively with the trypanosome 5'-3' exoribonuclease XRNA to a special granule at the posterior pole of the cell, indicating a connection between the two enzymes. RNAi depletion of ALPH1 is lethal and causes a massive increase in total mRNAs that are deadenylated, but have not yet started 5'-3' decay. These data suggest that ALPH1 acts downstream of deadenylation and upstream of mRNA degradation, consistent with a function in mRNA decapping. In vitro experiments show that recombinant, N-terminally truncated ALHP1 protein, but not a catalytically inactive mutant, sensitises the capped trypanosome spliced leader RNA to yeast Xrn1, but only if an RNA 5' polyphosphatase is included. This indicates that the decapping mechanism of ALPH1 differs from the decapping mechanism of Dcp2 by leaving more than one phosphate group at the mRNA's 5' end. This is the first reported function of a eukaryotic ApaH-like phosphatase, a bacterial-derived class of enzymes present in all phylogenetic super-groups of the eukaryotic kingdom. The substrates of eukaryotic ApaH-like phosphatases are unknown. However, the substrate of the related bacterial enzyme ApaH, diadenosine tetraphosphate, is highly reminiscent of a eukaryotic mRNA cap.

  1. Competence to consent to voluntary psychiatric hospitalization: a test of a standard proposed by APA. American Psychiatric Association.

    Science.gov (United States)

    Appelbaum, B C; Appelbaum, P S; Grisso, T

    1998-09-01

    In the wake of the U.S. Supreme Court's 1990 decision in Zinermon v. Burch, renewed attention has been given to capacities patients must have to be considered competent to consent to voluntary hospitalization. An American Psychiatric Association (APA) task force suggested that strong policy interests support the establishment of a low threshold for competence in this situation. The study examined whether, as previous research suggested, patients would have difficulty meeting even this lenient standard. One hundred voluntarily hospitalized psychiatric patients were read two brief paragraphs, one explaining the purposes of psychiatric hospitalization and and the other explaining policies for discharge. The paragraphs' readability measured about eighth-grade level. After each paragraph, participants were read two sets of questions, one testing recall of the presented information and the other testing recognition of the information in a true-false format. The scores of patients grouped by selected demographic and clinical variables were compared. The vast majority of patients were able to comprehend the information that the APA task force suggested was relevant to their decision. However, a subgroup of patients who were initially admitted involuntarily had significantly poorer performance and may constitute a group who need special educational efforts focused on the consequences of voluntary admission.

  2. La cita documental : elementos y ejemplos de referencias en los estilos de la MLA y de la APA. Documentos electrónicos ISO 690-2

    OpenAIRE

    Kolesas, Mabel; De-Volder, Carolina

    2008-01-01

    How to quote. Abridged style manual for writers of printed documents according to the Modern Language Association (MLA), the American Psychological Association (APA) and ISO 690-2 standards for E-documents.

  3. Développement d'un Gestionnaire Automatisé de Bibliographies selon les normes de l'American Psychological Association (GABI APA Style)

    OpenAIRE

    Thirion, Paul

    1992-01-01

    Nowadays, there are plenty of complete and user-friendly database management systems. However, most of them only produce poorly organized raw data, generally lacking of internal consistency. This situation remains awkward, especially for scientists who have regularly to report references in an extremely ruled international format. GABI APA Style was built in titis context. GABl APA Style is a reference manager software using the presentation rules of the American Psychological Association ...

  4. Performance and model of a full-scale up-flow anaerobic sludge blanket (UASB) to treat the pharmaceutical wastewater containing 6-APA and amoxicillin.

    Science.gov (United States)

    Chen, Zhiqiang; Wang, Hongcheng; Chen, Zhaobo; Ren, Nanqi; Wang, Aijie; Shi, Yue; Li, Xiaoming

    2011-01-30

    A full-scale test was conducted with an up-flow anaerobic sludge blanket (UASB) pre-treating pharmaceutical wastewater containing 6-aminopenicillanic acid (6-APA) and amoxicillin. The aim of the study is to investigate the performance of UASB in the condition of a high chemical oxygen demand (COD) loading rate from 12.57 to 21.02 kgm(-3)d(-1) and a wide pH from 5.57 to 8.26, in order to provide a reference for treating the similar chemical synthetic pharmaceutical wastewater containing 6-APA and amoxicillin. The results demonstrated that the UASB average percentage reduction in COD, 6-APA and amoxicillin were 52.2%, 26.3% and 21.6%, respectively. In addition, three models, built on the back propagation neural network (BPNN) theory and linear regression techniques were developed for the simulation of the UASB system performance in the biodegradation of pharmaceutical wastewater containing 6-APA and amoxicillin. The average error of COD, 6-APA and amoxicillin were -0.63%, 2.19% and 5.40%, respectively. The results indicated that these models built on the BPNN theory were well-fitted to the detected data, and were able to simulate and predict the removal of COD, 6-APA and amoxicillin by UASB. Crown Copyright © 2010. Published by Elsevier B.V. All rights reserved.

  5. Estratégias para o desenvolvimento motor, intelectual e social para beneficiários de APAES

    Directory of Open Access Journals (Sweden)

    Byanca Eugênia Duarte Silva

    2016-09-01

    Full Text Available A APAE é uma entidade filantrópica que desenvolve atividades de sensibilização, conscientização, prevenção, habilitação, reabilitação e inserção no mercado de trabalho. Dentro dessa perspectiva as atividades lúdicas são recurso pedagógico bastante importante, uma vez que além desenvolver as regras de comportamento pode desenvolver sua coordenação motora, suas habilidades visuais e auditivas, e seu raciocínio criativo e cognitivo.  Logo, o estudo objetivou evidenciar a importância das atividades lúdicas pedagógicas para o desenvolvimento da pessoa com deficiência, apresentando sugestões que propiciam este desenvolvimento em diferentes esferas. O presente estudo trata-se de um relato de experiência a partir do estágio realizado na Associação de Pais e Amigos dos Excepcionais (APAE da cidade de Cajazeiras-PB, em detrimento de um trabalho psicoterapêutico realizado com cinco adolescentes beneficiários, no período de outubro à novembro de 2015. Para este trabalho psicoterapêutico utilizou-se da sugestão de 10 atividades lúdicas pedagógicas que trabalham aspectos motores, cognitivos e sociais dos beneficiários. Este leque de atividades mostra as várias formas de possibilidades para que a pessoa com deficiência aperfeiçoe e/ou desenvolva sua capacidade intelectual, motora e social. Como também aumente sua apropriação do real através do simbólico, que são os objetos. Portanto as atividades lúdicas pedagógicas é um valioso recurso para impulsionar o desenvolvimento das pessoas com deficiência.Strategies for motor development, intellectual and social for beneficiaries of APAESAbstract: APAE is a philanthropic organization that develops awareness activities, awareness, prevention, habilitation, rehabilitation and integration into the labor market. Within this perspective the play activities are very important educational resource, as well develop the rules of behavior can develop their motor skills

  6. Vitamin-D receptor (VDR) gene polymorphisms (Taq-I & Apa-I) in Syrian healthy population.

    Science.gov (United States)

    Haddad, Shaden

    2014-12-01

    The vitamin D endocrine system regulates bone metabolism and calcium homeostasis as well as cellular proliferation and differentiation. Vitamin D receptor (VDR) mediates Vit-D activity, thus VDR gene polymorphisms may correlate with different diseases. This study aimed to determine the distribution of VDR gene (Taq-I and Apa-I) polymorphisms using a RFLP in unrelated normal healthy individuals of Syrian population. Allelic frequencies were 65% vs 35% and 66% vs 34% for T vs t and A vs a alleles, respectively. Genotype distribution was 36%, 58% and 6% for TT, Tt and tt and 42%, 47% and 10% for AA, Aa and aa, respectively. These results demonstrate that the frequency and distribution of the VDR polymorphisms in Syrian population are different from other populations worldwide.

  7. Anti-herpes simplex virus 1 and immunomodulatory activities of a poly-γ- glutamic acid from Bacillus horneckiae strain APA of shallow vent origin.

    Science.gov (United States)

    Marino-Merlo, Francesca; Papaianni, Emanuela; Maugeri, Teresa L; Zammuto, Vincenzo; Spanò, Antonio; Nicolaus, Barbara; Poli, Annarita; Di Donato, Paola; Mosca, Claudia; Mastino, Antonio; Gugliandolo, Concetta

    2017-10-01

    Herpes simplex virus type 1 (HSV-1) is responsible of common and widespread viral infections in humans through the world, and of rare, but extremely severe, clinical syndromes in the central nervous system. The emergence of resistant strains to drugs actually in use encourages the searching for novel antiviral compounds, including those of natural origin. In this study, the recently described poly-γ-glutamic acid (γ-PGA-APA), produced by the marine thermotolerant Bacillus horneckiae strain APA, and previously shown to possess biological and antiviral activity, was evaluated for its anti-HSV-1 and immunomodulatory properties. The biopolymer hindered the HSV-1 infection in the very early phase of virus replication. In addition, the γ-PGA-APA was shown to exert low cytotoxicity and noticeable immunomodulatory activities towards TNF-α and IL-1β gene expression. Moreover, the capacity to positively modulate the transcriptional activity of the cytokine genes was paired with increased level of activation of the transcription factor NF-kB by γ-PGA-APA. Overall, as non-cytotoxic biopolymer able to contribute in the antiviral defense against HSV-1, γ-PGA-APA could lead to the development of novel natural drugs for alternative therapies.

  8. “Citation Style Language” Uygulaması: APA Kaynak Gösterme Biçiminin Türkçeye Adaptasyonu=“Citation Style Language” Application: The Adaptation of APA Style to Turkish Language

    OpenAIRE

    Kasım Binici

    2013-01-01

    Bibliyografya yönetim programları, araştırma metinlerin yazımında yazarlara büyük avantajlar sağlamaktadır.Akademik çevrede EndNote, RefWorks, Zotero, Mendeley en popüler yazılımlardır. Türkçe kaynak gösterme kurallarının tanımlı olduğu biçim dosyalarının olmaması nedeniyle araştırma metni yazımında bu programlar işlevsiz kalmaktadır. Bu çalışmada, APA kaynak gösterme biçiminin Türkçeye adaptasyonu sağlanarak CSL uygulaması ile biçim dosyasında kodlar yazılmıştır. Yeni biçim dosyası Zotero...

  9. Calamitic Smectic A-Polar Smectic APA Transition Observed in Bent Molecules with Large Bent-Angle Central Core of 4,6-Dichlorobenzene and Alkylthio Terminal Tail

    Science.gov (United States)

    Nguyen, Ha; Kang, Sungmin; Tokita, Masatoshi; Watanabe, Junji

    2011-07-01

    New homologs of bent molecules with a large bent-angle central core of 4,6-dichloro benzene and an alkylthio terminal tail have been synthesized. Although the corresponding alkoxy-tail homologs show only the calamitic phases because of its large bent angles around 160°, the new homologs with an alkylthio tail exhibit the antiferroelectric smectic APA (SmAPA) banana phase that is transformed on cooling from the calamitic smectic A (SmA) phase. The biaxial polar packing of bent molecules in the SmAPA phase is considered to arise from the hindered rotation around the molecular long axis due to the expansion of the mesophase temperatures to a lower temperature region. This study indicates that the bent molecules, even with a large bent angle, have the potential to form a switchable banana phase with a remarkable decrease in its phase temperature range to around 60 °C.

  10. [Phase transfer catalyzed bioconversion of penicillin G to 6-APA by immobilized penicillin acylase in recyclable aqueous two-phase systems with light/pH sensitive copolymers].

    Science.gov (United States)

    Jin, Ke-ming; Cao, Xue-jun; Su, Jin; Ma, Li; Zhuang, Ying-ping; Chu, Ju; Zhang, Si-liang

    2008-03-01

    Immobilized penicillin acylase was used for bioconversion of penicillin PG into 6-APA in aqueous two-phase systems consisting of a light-sensitive polymer PNBC and a pH-sensitive polymer PADB. Partition coefficients of 6-APA was found to be about 5.78 in the presence of 1% NaCl. Enzyme kinetics showed that the reaction reached equilibrium at roughly 7 h. The 6-APA mole yields were 85.3% (pH 7.8, 20 degrees C), with about 20% increment as compared with the reaction of single aqueous phase buffer. The partition coefficient of PG (Na) varied scarcely, while that of the product, 6-APA and phenylacetic acid (PA) significantly varied due to Donnan effect of the phase systems and hydrophobicity of the products. The variation of the partition coefficients of the products also affected the bioconversion yield of the products. In the aqueous two-phase systems, the substrate, PG, the products of 6-APA and PA were biased in the top phase, while immobilized penicillin acylase at completely partitioned at the bottom. The substrate and PG entered the bottom phase, where it was catalyzed into 6-APA and PA and entered the top phase. Inhibition of the substrate and products was removed to result in improvement of the product yield, and the immobilized enzyme showed higher efficiency than the immobilized cells and occupied smaller volume. Compared with the free enzyme, immobilized enzyme had greater stability, longer life-time, and was completely partitioned in the bottom phase and recycle. Bioconversion in two-phase systems using immobilized penicillin acylase showed outstanding advantage. The light-sensitive copolymer forming aqueous two-phase systems could be recovered by laser radiation at 488 nm or filtered 450 nm light, while pH-sensitive polymer PADB could be recovered at the isoelectric point (pH 4.1). The recovery of the two copolymers was between 95% and 99%.

  11. The O-mannosylation and production of recombinant APA (45/47 KDa protein from Mycobacterium tuberculosis in Streptomyces lividans is affected by culture conditions in shake flasks

    Directory of Open Access Journals (Sweden)

    Gamboa-Suasnavart Ramsés A

    2011-12-01

    Full Text Available Abstract Background The Ala-Pro-rich O-glycoprotein known as the 45/47 kDa or APA antigen from Mycobacterium tuberculosis is an immunodominant adhesin restricted to mycobacterium genus and has been proposed as an alternative candidate to generate a new vaccine against tuberculosis or for diagnosis kits. In this work, the recombinant O-glycoprotein APA was produced by the non-pathogenic filamentous bacteria Streptomyces lividans, evaluating three different culture conditions. This strain is known for its ability to produce heterologous proteins in a shorter time compared to M. tuberculosis. Results Three different shake flask geometries were used to provide different shear and oxygenation conditions; and the impact of those conditions on the morphology of S. lividans and the production of rAPA was characterized and evaluated. Small unbranched free filaments and mycelial clumps were found in baffled and coiled shake flasks, but one order of magnitude larger pellets were found in conventional shake flasks. The production of rAPA is around 3 times higher in small mycelia than in larger pellets, most probably due to difficulties in mass transfer inside pellets. Moreover, there are four putative sites of O-mannosylation in native APA, one of which is located at the carboxy-terminal region. The carbohydrate composition of this site was determined for rAPA by mass spectrometry analysis, and was found to contain different glycoforms depending on culture conditions. Up to two mannoses residues were found in cultures carried out in conventional shake flasks, and up to five mannoses residues were determined in coiled and baffled shake flasks. Conclusions The shear and/or oxygenation parameters determine the bacterial morphology, the productivity, and the O-mannosylation of rAPA in S. lividans. As demonstrated here, culture conditions have to be carefully controlled in order to obtain recombinant O-glycosylated proteins with similar "quality" in bacteria

  12. The O-mannosylation and production of recombinant APA (45/47 KDa) protein from Mycobacterium tuberculosis in Streptomyces lividans is affected by culture conditions in shake flasks.

    Science.gov (United States)

    Gamboa-Suasnavart, Ramsés A; Valdez-Cruz, Norma A; Cordova-Dávalos, Laura E; Martínez-Sotelo, José A; Servín-González, Luis; Espitia, Clara; Trujillo-Roldán, Mauricio A

    2011-12-20

    The Ala-Pro-rich O-glycoprotein known as the 45/47 kDa or APA antigen from Mycobacterium tuberculosis is an immunodominant adhesin restricted to mycobacterium genus and has been proposed as an alternative candidate to generate a new vaccine against tuberculosis or for diagnosis kits. In this work, the recombinant O-glycoprotein APA was produced by the non-pathogenic filamentous bacteria Streptomyces lividans, evaluating three different culture conditions. This strain is known for its ability to produce heterologous proteins in a shorter time compared to M. tuberculosis. Three different shake flask geometries were used to provide different shear and oxygenation conditions; and the impact of those conditions on the morphology of S. lividans and the production of rAPA was characterized and evaluated. Small unbranched free filaments and mycelial clumps were found in baffled and coiled shake flasks, but one order of magnitude larger pellets were found in conventional shake flasks. The production of rAPA is around 3 times higher in small mycelia than in larger pellets, most probably due to difficulties in mass transfer inside pellets. Moreover, there are four putative sites of O-mannosylation in native APA, one of which is located at the carboxy-terminal region. The carbohydrate composition of this site was determined for rAPA by mass spectrometry analysis, and was found to contain different glycoforms depending on culture conditions. Up to two mannoses residues were found in cultures carried out in conventional shake flasks, and up to five mannoses residues were determined in coiled and baffled shake flasks. The shear and/or oxygenation parameters determine the bacterial morphology, the productivity, and the O-mannosylation of rAPA in S. lividans. As demonstrated here, culture conditions have to be carefully controlled in order to obtain recombinant O-glycosylated proteins with similar "quality" in bacteria, particularly, if the protein activity depends on the

  13. Impactos ambientais na área de proteção ambiental (APA de Guaratuba, Paraná, BrasilL, sob o ponto de vista de moradores tradicionais / Environmental impacts in the Environmental Protection Area (APA of Guaratuba, State of Paraná, Brazil: the traditional communities point-of-view

    Directory of Open Access Journals (Sweden)

    Raphael Telles Kantek

    2009-08-01

    Full Text Available The present research was carried out in the Environmental Protection Area (APA of Guaratuba,State of Paraná, to analyze the environmental impacts of the APA as assessed by the local traditionalcommunities. Two instruments were used: Geographical Information System (GIS and Discourseof the Collective Subject (DSC. Although the GIS covers more situations that the DSC, results weresimilar. The pressures are complex and the analysis must involve the natural and traditionalcommunities.

  14. Improving the industrial production of 6-APA: enzymatic hydrolysis of penicillin G in the presence of organic solvents.

    Science.gov (United States)

    Abian, Olga; Mateo, César; Fernández-Lorente, Gloria; Guisán, José M; Fernández-Lafuente, Roberto

    2003-01-01

    The hydrolysis of penicillin G in the presence of an organic solvent, used with the purpose of extracting it from the culture medium, may greatly simplify the industrial preparation of 6-APA. However, under these conditions, PGA immobilized onto Eupergit displays very low stability (half-life of 5 h in butanone-saturated water) and a significant degree of inhibition by the organic solvent (30%). The negative effect of the organic solvent strongly depended on the type of solvent utilized: water saturated with butanone (around 28% v/v) had a much more pronounced negative effect than that of methylisobutyl ketone (MIBK) (solubility in water was only 2%). These problems were sorted out by using a new penicillin G acylase derivative designed to work in the presence of organic solvents (with each enzyme molecule surrounded by an hydrophilic artificial environment) and a suitable organic solvent (MIBK). Using such solvent, this derivative kept its activity unaltered for 1 week at 32 degrees C. Moreover, the enzyme activity was hardly inhibited by the presence of the organic solvent. In this way, the new enzyme derivative thus prepared enables simplification of the industrial hydrolysis of penicillin G.

  15. The psychometric properties of the personality inventory for DSM-5 in an APA DSM-5 field trial sample.

    Science.gov (United States)

    Quilty, Lena C; Ayearst, Lindsay; Chmielewski, Michael; Pollock, Bruce G; Bagby, R Michael

    2013-06-01

    Section 3 of the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) includes a hybrid model of personality pathology, in which dimensional personality traits are used to derive one of seven categorical personality disorder diagnoses. The Personality Inventory for DSM-5 (PID-5) was developed by the DSM-5 Personality and Personality Disorders workgroup and their consultants to produce a freely available instrument to assess the personality traits within this new system. To date, the psychometric properties of the PID-5 have been evaluated primarily in undergraduate student and community adult samples. In the current investigation, we extend this line of research to a psychiatric patient sample who participated in the APA DSM-5 Field Trial (Centre for Addiction and Mental Health site). A total of 201 psychiatric patients (102 men, 99 women) completed the PID-5 and the Revised NEO Personality Inventory (NEO PI-R). The internal consistencies of the PID-5 domain and facet trait scales were acceptable. Results supported the unidimensional structure of all trait scales but one, and the convergence between the PID-5 and analogous NEO PI-R scales. Evidence for discriminant validity was mixed. Overall, the current investigation provides support for the psychometric properties of this diagnostic instrument in psychiatric samples.

  16. Empowerment of person with intellectual deficiency to the labor market in an APAE the south of Santa Catarina

    Directory of Open Access Journals (Sweden)

    Laysa Karoline Cardoso

    2016-12-01

    Full Text Available It is about a case study in an APAE the south of Santa Catarina, to know about the adopted actions from the institution in the empowerment to the inclusion of people with intellectual deficiency in the labor market. Nowadays the number of people with intellectual deficiency in the formal market is significantly smaller than the number of people with another kinds of deficiency and, in this direction, it is intended to enhance the consideration to the importance of this people empowerment. The design is from a qualitative nature and to the data collection was used the documentary analysis and the semi-directed interviews were done with the teachers and the multi-professional team involved in the professional empowerment. The data were analyzed based on the contents analysis. These are conclude as barriers to the inclusion to the labor market: the low profile from the students to the available job vacancy. Untying difficulty from the student’s family concerning about the earned benefit and family overprotection.

  17. Prevalence of medicines used by mentally-ill individuals of APAE, in Londrina Prevalência de medicamentos utilizados por portadores de retardo mental da APAE de Londrina-Pr

    Directory of Open Access Journals (Sweden)

    Bruna Polacchine Da Silva

    2005-10-01

    Full Text Available Mental retardation (MR, after years of mites and beliefs, finally was considered to be a neurological affection that should be treated by a medical intervention. Psychotropic drugs, if correctly prescribed, are able to improve the capacity of MR individuals to productively interact socially and reintegrate themselves to the society. This work has as an objective to quantify, by a descriptive study, the frequency of use of medicines by students of the APAE (Associação de Pais e Amigos dos Excepcionais from Londrina-PR, characterize those drugs and relate them to mental pathologies of major prevalence in the institution. To accomplish the objectives, a pool was conducted on a population of 147 students registered during the period from January/1989 to May/ 2003. The results shown the following medicines: antiepiletic (52.4%, neuroleptics (3.4%, hematopoietics (2.7%, anticolinergics and pro-kinetics agents (0.7% each. Fenobarbital was the most evident among the antiepiletic (29.8%. The prevalence of those drugs was higher among individuals with cerebral palsy (62.1% and lower for the Down syndrome group (17,24%. As a conclusion, we consider necessary to conduct research projects focusing on the dynamic of the personnel affected by MR, as well as to provide social assistance to destitute families. O retardo mental (RM, após anos de crenças e misticismos, finalmente passou a ser considerado uma afecção neurológica que deve ser tratada com intervenção médica. As drogas psicotrópicas, se administradas corretamente, podem permitir que os acometidos de RM recuperem a capacidade de interação social produtiva e reintegrem-se à sociedade. Este trabalho teve como objetivo verificar, por meio de estudo descritivo, a freqüência da utilização de medicamentos utilizados pelos alunos da APAE (Associação de Pais e Amigos dos Excepcionais de Londrina-PR, caracterizar essas drogas e relacionálas com as patologias mentais de maior prevalência na

  18. Are adolescents less mature than adults?: minors' access to abortion, the juvenile death penalty, and the alleged APA "flip-flop".

    Science.gov (United States)

    Steinberg, Laurence; Cauffman, Elizabeth; Woolard, Jennifer; Graham, Sandra; Banich, Marie

    2009-10-01

    The American Psychological Association's (APA's) stance on the psychological maturity of adolescents has been criticized as inconsistent. In its Supreme Court amicus brief in Roper v. Simmons (2005), which abolished the juvenile death penalty, APA described adolescents as developmentally immature. In its amicus brief in Hodgson v. Minnesota (1990), however, which upheld adolescents' right to seek an abortion without parental involvement, APA argued that adolescents are as mature as adults. The authors present evidence that adolescents demonstrate adult levels of cognitive capability earlier than they evince emotional and social maturity. On the basis of this research, the authors argue that it is entirely reasonable to assert that adolescents possess the necessary skills to make an informed choice about terminating a pregnancy but are nevertheless less mature than adults in ways that mitigate criminal responsibility. The notion that a single line can be drawn between adolescence and adulthood for different purposes under the law is at odds with developmental science. Drawing age boundaries on the basis of developmental research cannot be done sensibly without a careful and nuanced consideration of the particular demands placed on the individual for "adult-like" maturity in different domains of functioning. Copyright 2009 APA

  19. MAPEAMENTO DA PRODUÇÃO CIENTÍFICA VEICULADA EM PERIÓDICOS SOBRE A TEMÁTICA APAE (2000-2015

    Directory of Open Access Journals (Sweden)

    João Henrique da SILVA

    2017-07-01

    Full Text Available The present research had as objective to analyze the scientific productions in format of articles conveyed in periods on the thematic ‘People with Deficiencies Parents’ Association (APAE. It is a qualitative-quantitative study, a bibliometric methodological approach and content analysis. The methodological procedures were developed in three stages that include the theoretical and methodological preparation phase, data collection and recording, and systematization and analysis of the results. The results indicated that 61 articles published in 38 different journals and elaborated by 171 authors, 178 contributions, between the period 2000-2015. A total of 46 different institutions were identified, providing education services concentrated in the south and southeast regions of the country. It was also verified that the subjects are related in the area of Health and Education. The academic production analyzed presents different objectives and results obtained on the APAE. The research focuses on topics related to human subjectivity, family and institutions, social inclusion and the educational process of people with disabilities. The findings of the articles unfold the objectives of the work, showing the relevance of the actions developed within the APAE units and the influences of the family and political environment. Therefore, it is reiterated that APAE is a philanthropic institution that seeks to develop actions in the area of health, education and social assistance for people with disabilities.

  20. Effect of oxygen and nitroaromatic cell radiosensitizers on radiation-induced cleavage of internucleotide bonds: ApA, dApA, and poly(A)

    International Nuclear Information System (INIS)

    Raleigh, J.A.; Kremers, W.; Whitehouse, R.

    1975-01-01

    Irradiation of the dinucleoside monophosphates ApA and dApA in deoxygenated solution leads to a preferential cleavage of the 3' end of the internucleotide bond. Cleavage at the 3' bond is favored to the extent of 2 to 1 over 5' cleavage. Oxygen and nitroaromatic compounds inhibit 3' bond breaking in ApA and dApA in agreement with earlier findings from studies of 3'- and 5'-mononucleotides. In contrast to the mononucleotide results, no enhancement of 5' cleavage is observed for ApA and dApA irradiated in the presence of oxygen or the nitroaromatic additives. The over-all effect of the additives is to decrease the combined (3' and 5') yield of internucleotide bond breaking in ApA and dApA. This phenomenon is also observed for polyadenylic acid in the presence of the nitroaromatics. Oxygen marginally enhances internucleotide bond breaking in polyadenylic acid (factor 1.1) over that seen in deoxygenated solution. Postirradiation alkaline hydrolysis of dApA leads to further ester cleavage revealing the presence of radiation-induced alkali-labile bonds. The number of these bonds decreases in the order oxygen greater than nitrofurans greater than nitrobenzenes approximately irradiation in the absence of additives

  1. Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen activator (aPA) and induces proinflammatory cytokine in human corneal epithelial cells.

    Science.gov (United States)

    Tripathi, Trivendra; Abdi, Mahshid; Alizadeh, Hassan

    2014-05-29

    Acanthamoeba plasminogen activator (aPA) is a serine protease elaborated by Acanthamoeba trophozoites that facilitates the invasion of trophozoites to the host and contributes to the pathogenesis of Acanthamoeba keratitis (AK). The aim of this study was to explore if aPA stimulates proinflammatory cytokine in human corneal epithelial (HCE) cells via the protease-activated receptors (PARs) pathway. Acanthamoeba castellanii trophozoites were grown in peptone-yeast extract glucose for 7 days, and the supernatants were collected and centrifuged. The aPA was purified using the fast protein liquid chromatography system, and aPA activity was determined by zymography assays. Human corneal epithelial cells were incubated with or without aPA (100 μg/mL), PAR1 agonists (thrombin, 10 μM; TRAP-6, 10 μM), and PAR2 agonists (SLIGRL-NH2, 100 μM; AC 55541, 10 μM) for 24 and 48 hours. Inhibition of PAR1 and PAR2 involved preincubating the HCE cells for 1 hour with the antagonist of PAR1 (SCH 79797, 60 μM) and PAR2 (FSLLRY-NH2, 100 μM) with or without aPA. Human corneal epithelial cells also were preincubated with PAR1 and PAR2 antagonists and then incubated with or without PAR1 agonists (thrombin and TRAP-6) and PAR2 agonists (SLIGRL-NH2 and AC 55541). Expression of PAR1 and PAR2 was examined by quantitative RT-PCR (qRT-PCR), flow cytometry, and immunocytochemistry. Interleukin-8 expression was quantified by qRT-PCR and ELISA. Human corneal epithelial cells constitutively expressed PAR1 and PAR2 mRNA. Acanthamoeba plasminogen activator and PAR2 agonists significantly upregulated PAR2 mRNA expression (1- and 2-fold, respectively) (P aPA, and PAR2 agonists induced PAR2 mRNA expression in HCE cells (P aPA, significantly upregulated PAR1 mRNA expression, which was significantly inhibited by PAR1 antagonist in HCE cells. Acanthamoeba plasminogen activator and PAR2 agonists stimulated IL-8 mRNA expression and protein production, which is significantly diminished by PAR2 antagonist

  2. Do Biochemical Markers and Apa I Polymorphism in IGF-II Gene Play a Role in the Association of Birth Weight and Later BMI?

    Science.gov (United States)

    Wu, Junqing; Ren, Jingchao; Li, Yuyan; Wu, Yinjie; Gao, Ersheng

    2013-01-01

    The aim of the study was to explore the mechanisms underlying the association of birth weight with later body mass index (BMI) from the biochemical markers related to metabolism and the Apa I polymorphism in IGF-II gene. A total of 300 children were selected randomly from the Macrosomia Birth Cohort in Wuxi, China. The height and weight were measured and blood samples were collected. Plasma concentrations of 8 biochemical markers were detected. Apa I polymorphism was analyzed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Biochemical markers were detected for 296 subjects and 271 subjects were genotyped for the Apa I polymorphism. No association was found between birth weight and 8 biochemical markers. In boys, the BMIs of AA, AG and GG genotypes were 16.10 ± 2.24 kg/m(2), 17.40 ± 3.20 kg/m(2), 17.65 ± 2.66 kg/m(2). And there was statistical difference among the three genotypes. But in girls, there was no statistical difference. The birth weights of AA, AG and GG genotypes were 3751.13 ± 492.43 g, 3734.00 ± 456.88 g, 3782.00 ± 461.78 g. And there was no statistical difference among the three genotypes. Biochemical markers are not associated with birth weight. Apa I polymorphism may be related to childhood BMI, but it may be not associated with birth weight. Therefore, biochemical markers and Apa I polymorphism might not play a role in the association of birth weight and BMI.

  3. Journal article reporting standards for qualitative primary, qualitative meta-analytic, and mixed methods research in psychology: The APA Publications and Communications Board task force report.

    Science.gov (United States)

    Levitt, Heidi M; Bamberg, Michael; Creswell, John W; Frost, David M; Josselson, Ruthellen; Suárez-Orozco, Carola

    2018-01-01

    The American Psychological Association Publications and Communications Board Working Group on Journal Article Reporting Standards for Qualitative Research (JARS-Qual Working Group) was charged with examining the state of journal article reporting standards as they applied to qualitative research and with generating recommendations for standards that would be appropriate for a wide range of methods within the discipline of psychology. These standards describe what should be included in a research report to enable and facilitate the review process. This publication marks a historical moment-the first inclusion of qualitative research in APA Style, which is the basis of both the Publication Manual of the American Psychological Association (APA, 2010) and APA Style CENTRAL, an online program to support APA Style. In addition to the general JARS-Qual guidelines, the Working Group has developed standards for both qualitative meta-analysis and mixed methods research. The reporting standards were developed for psychological qualitative research but may hold utility for a broad range of social sciences. They honor a range of qualitative traditions, methods, and reporting styles. The Working Group was composed of a group of researchers with backgrounds in varying methods, research topics, and approaches to inquiry. In this article, they present these standards and their rationale, and they detail the ways that the standards differ from the quantitative research reporting standards. They describe how the standards can be used by authors in the process of writing qualitative research for submission as well as by reviewers and editors in the process of reviewing research. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  4. Usos e conflitos na APA do Pouso Alto (GO): uma abordagem sobre a percepção dos atores locais de Colinas do Sul e Cavalcante

    OpenAIRE

    Ferreira, Lara Cristine Gomes; Almeida, Maria Geralda de

    2014-01-01

    v. 8, n. 1, p.215-230, abr/2014. A Área de Proteção Ambiental – APA do Pouso Alto, criada no ano de 2001 no nordeste de Goiás, inserida na categoria de Unidade de Uso Sustentável, tem como objetivo principal a preservação dos recursos naturais aliada ao uso sustentável da área. Contudo, mesmo sendo a APA de suma importância em uma região que apresenta a maior área de Cerrado preservado em Goiás e com riquíssima biodiversidade, a criação e implantação dela passou e passa por grandes conflit...

  5. Introduction to the special issue: 50th anniversary of APA Division 28: The past, present, and future of psychopharmacology and substance abuse.

    Science.gov (United States)

    Stoops, William W; Sigmon, Stacey C; Evans, Suzette M

    2016-08-01

    This is an introduction to the special issue "50th Anniversary of APA Division 28: The Past, Present, and Future of Psychopharmacology and Substance Abuse." Taken together, the scholarly contributions included in this special issue serve as a testament to the important work conducted by our colleagues over the past five decades. Division 28 and its members have advanced and disseminated knowledge on the behavioral effects of drugs, informed efforts to prevent and treat substance abuse, and influenced education and policy issues more generally. As past and current leaders of the division, we are excited to celebrate 50 years of Division 28 and look forward to many more successful decades for our division and its members. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  6. Association of vitamin D receptor gene polymorphism (TaqI and Apa1) with bone mineral density in North Indian postmenopausal women.

    Science.gov (United States)

    Ahmad, Israr; Jafar, Tabrez; Mahdi, Farzana; Ameta, Keerti; Arshad, Md; Das, Siddharth Kumar; Waliullah, Shah; Rizvi, Imran; Mahdi, Abbas Ali

    2018-06-15

    Vitamin D receptor (VDR) gene has an important role as a candidate gene for the regulation of bone mass in osteoporosis. However, its association with bone mineral density (BMD) is controversial and has not been established in different ethnic populations. To enhance the understanding of VDR gene polymorphism in the context of BMD, we investigated the plausible genetic association of TaqI and ApaI polymorphism with BMD in North Indian postmenopausal women with osteoporosis.254 osteoporotic women (Age 55.82 ± 6.91) and 254 postmenopausal non osteoporotic women (Age 54.76 ± 6.26) were included in the study. VDR TaqI and ApaI polymorphism were determined by PCR (polymerase chain reaction) and RFLP (restriction fragment length polymorphism). BMD was assessed by dual energy X-ray absorptiometry (DXA) at the lumbar spine (L 1 -L 4 ), hip, forearm and femoral neck. The average BMD with TT genotype was significantly lower at lumbar spine, hip and forearm. The Frequency of TT genotype and t allele was significantly high in osteoporotic women when compared with controls. The average BMD with Aa genotype was higher in ApaI. Furthermore, comparison of frequency distribution of genotype and allele for VDR ApaI between osteoporotic patients and controls did not show any significant difference. Our findings revealed that TaqI gene TT genotype was associated with low BMD in North Indian osteoporotic women. Moreover, TT genotype and t allele associated significantly with osteoporosis in postmenopausal women. Therefore, VDR TaqI gene is an important determinant of risk factor for osteoporosis. Copyright © 2018 Elsevier B.V. All rights reserved.

  7. Preparation, crystallization and preliminary X-ray analysis of XC2382, an ApaG protein of unknown structure from Xanthomonas campestris

    International Nuclear Information System (INIS)

    Chin, Ko-Hsin; Chou, Chia-Cheng; Lee, Cheng-Chung; Shr, Hui-Lin; Lyu, Ping-Chiang; Wang, Andrew H.-J.; Chou, Shan-Ho

    2005-01-01

    A putative ApaG gene product from X. campestris pv. campestris was overexpressed in E. coli, purified and crystallized. The crystals diffracted to a resolution of at least 2.3 Å. Xanthomonas campestris pv. campestris is the causative agent of black rot, one of the major worldwide diseases of cruciferous crops. Its genome encodes approximately 4500 proteins, roughly one third of which have unknown function. XC2382 is one such protein, with a MW of 14.2 kDa. Based on a bioinformatics study, it was annotated as an ApaG gene product that serves multiple functions. The ApaG protein has been overexpressed in Escherichia coli, purified and crystallized using the hanging-drop vapour-diffusion method. The crystals diffracted to a resolution of at least 2.30 Å. They are tetragonal and belong to space group P4 1/3 , with unit-cell parameters a = b = 57.6, c = 122.9 Å. There are two, three or four molecules in the asymmetric unit

  8. O-mannosylation of the Mycobacterium tuberculosis adhesin Apa is crucial for T cell antigenicity during infection but is expendable for protection.

    Science.gov (United States)

    Nandakumar, Subhadra; Kannanganat, Sunil; Dobos, Karen M; Lucas, Megan; Spencer, John S; Fang, Sunan; McDonald, Melissa A; Pohl, Jan; Birkness, Kristin; Chamcha, Venkateswarlu; Ramirez, Melissa V; Plikaytis, Bonnie B; Posey, James E; Amara, Rama Rao; Sable, Suraj B

    2013-01-01

    Glycosylation is the most abundant post-translational polypeptide chain modification in nature. Although carbohydrate modification of protein antigens from many microbial pathogens constitutes important components of B cell epitopes, the role in T cell immunity is not completely understood. Here, using ELISPOT and polychromatic flow cytometry, we show that O-mannosylation of the adhesin, Apa, of Mycobacterium tuberculosis (Mtb) is crucial for its T cell antigenicity in humans and mice after infection. However, subunit vaccination with both mannosylated and non-mannosylated Apa induced a comparable magnitude and quality of T cell response and imparted similar levels of protection against Mtb challenge in mice. Both forms equally improved waning BCG vaccine-induced protection in elderly mice after subunit boosting. Thus, O-mannosylation of Apa is required for antigenicity but appears to be dispensable for its immunogenicity and protective efficacy in mice. These results have implications for the development of subunit vaccines using post-translationally modified proteins such as glycoproteins against infectious diseases like tuberculosis.

  9. A história da escola de educação especial Bem Me Quer – APAE de Toledo – Paraná

    Directory of Open Access Journals (Sweden)

    Ireni Marilene Zago Figueiredo

    2012-08-01

    Full Text Available A APAE de Toledo - PR, fundada no ano de 1974, foi a primeira instituição criada para oferecer o atendimento educacional e social para as pessoas com deficiência no município. Sua instalação ocorreu devido ao empenho de lideranças comunitárias e pais de pessoas com deficiência, que sentiram a necessidade de ter na cidade uma entidade, instituição ou escola para atendimento especializado. Depois de 37 anos de serviços prestados a comunidade toledana, a APAE, que mantém a Escola Especial Bem Me Quer, se destaca como uma das instituições mais importantes na região Oeste do Paraná, oferecendo atendimento especializado para crianças com deficiência na Educação Infantil e no Ensino Fundamental, bem como para os jovens acima de 18 anos no Setor Profissionalizante. O artigo trata, portanto, do histórico da APAE de Toledo – PR, demonstrando que o Setor Profissionalizante foi instalado, em 1996, e reorganizado, em 1998, a partir do Processo de Educação Profissional e Colocação no Trabalho (PECT, com os programas de Iniciação Profissional, Qualificação Profissional e Colocação no Trabalho.

  10. Apa-I polymorphism in VDR gene is related to metabolic syndrome in polycystic ovary syndrome: a cross-sectional study.

    Science.gov (United States)

    Santos, Betânia Rodrigues; Lecke, Sheila Bunecker; Spritzer, Poli Mara

    2018-04-18

    Polycystic ovary syndrome (PCOS) is a common endocrine disorder determined by polygenic traits as well as environmental factors. Lower vitamin D levels have been detected in PCOS women and related to hormone and metabolic disturbances. Vitamin D acts in tissues through the vitamin D receptor (VDR). VDR gene variants have been associated with worse metabolic profile in the general population. We investigated the genotype and haplotype distribution of the Bsm-I (rs1544410), Apa-I (rs7975232), and Taq-I (rs731236) VDR gene polymorphisms in PCOS and non-hirsute women from southern Brazil. We further investigated the associations of these gene variants and their haplotypes with PCOS, vitamin D levels, and metabolic abnormalities, including the metabolic syndrome (MetS). A group of 191 women with PCOS (Rotterdam criteria) and 100 non-hirsute controls with regular ovulatory cycles were genotyped for all polymorphisms by real-time PCR, with allelic discrimination assays. MetS and the cutoffs for its isolated components were defined in accordance with the Joint Scientific Statement. Women with PCOS were younger and had significantly higher BMI and total testosterone levels than controls (p Apa-I entailed higher risk of MetS in PCOS (OR: 2.133; 95% CI 1.020-4.464, p = 0.042), and was associated with higher systolic blood pressure (p = 0.009), total cholesterol (p = 0.040), and LDL-cholesterol (p = 0.038) in both PCOS and control groups (two-way ANOVA). The frequencies of VDR haplotypes were similar in PCOS and control women. The present results suggest that the Apa-I variant in VDR gene may be associated with MetS in southern Brazilian women with PCOS, and with blood pressure, total cholesterol, and LDL-c in women with and without PCOS.

  11. NASA AVOSS Fast-Time Models for Aircraft Wake Prediction: User's Guide (APA3.8 and TDP2.1)

    Science.gov (United States)

    Ahmad, Nash'at N.; VanValkenburg, Randal L.; Pruis, Matthew J.; Limon Duparcmeur, Fanny M.

    2016-01-01

    NASA's current distribution of fast-time wake vortex decay and transport models includes APA (Version 3.8) and TDP (Version 2.1). This User's Guide provides detailed information on the model inputs, file formats, and model outputs. A brief description of the Memphis 1995, Dallas/Fort Worth 1997, and the Denver 2003 wake vortex datasets is given along with the evaluation of models. A detailed bibliography is provided which includes publications on model development, wake field experiment descriptions, and applications of the fast-time wake vortex models.

  12. The h index of the presidents of the American Psychological Association (APA through journal articles included in the Web of Science database

    Directory of Open Access Journals (Sweden)

    Gualberto Buela-Casal

    2011-01-01

    Full Text Available El presente estudio descriptivo analiza los índices h de los presidentes de la American Psychological Association (APA desde 1940 hasta la actualidad. El índice h se calcula teniendo en cuenta el número de artículos publicados en las revistas de la Web of Science (WOS y las citas recibidas por los mismos en dicha base de datos. No se estableció un periodo de búsqueda y, por tanto, se analizaron todos los resultados incluidos en la WOS. El número total de resultados analizados fue de 16.676, de los cuales 3.734 fueron de los presidentes de la APA. Los resultados se presentan en forma de ranking y ponen de manifiesto que Albert Bandura y Alan Kazdin son los presidentes con un índice h más elevado, y en entre estos y los demás existe una diferencia considerable. Los resultados hacen especular que el criterio de productividad en artículos científicos no fue el criterio más importante para presidir esta institución.

  13. Hydrolysis of ibuprofenoyl-CoA and other 2-APA-CoA esters by human acyl-CoA thioesterases-1 and -2 and their possible role in the chiral inversion of profens.

    Science.gov (United States)

    Qu, Xiao; Allan, Amanda; Chui, Grace; Hutchings, Thomas J; Jiao, Ping; Johnson, Lawrence; Leung, Wai Y; Li, Portia K; Steel, Georgina R; Thompson, Andrew S; Threadgill, Michael D; Woodman, Timothy J; Lloyd, Matthew D

    2013-12-01

    Ibuprofen and related 2-arylpropanoic acid (2-APA) drugs are often given as a racemic mixture and the R-enantiomers undergo activation in vivo by metabolic chiral inversion. The chiral inversion pathway consists of conversion of the drug to the coenzyme A ester (by an acyl-CoA synthetase) followed by chiral inversion by α-methylacyl-CoA racemase (AMACR; P504S). The enzymes responsible for hydrolysis of the product S-2-APA-CoA ester to the active S-2-APA drug have not been identified. In this study, conversion of a variety of 2-APA-CoA esters by human acyl-CoA thioesterase-1 and -2 (ACOT-1 and -2) was investigated. Human recombinant ACOT-1 and -2 (ACOT-1 and -2) were both able to efficiently hydrolyse a variety of 2-APA-CoA substrates. Studies with the model substrates R- and S-2-methylmyristoyl-CoA showed that both enzymes were able to efficiently hydrolyse both of the epimeric substrates with (2R)- and (2S)- methyl groups. ACOT-1 is located in the cytosol and is able to hydrolyse 2-APA-CoA esters exported from the mitochondria and peroxisomes for inhibition of cyclo-oxygenase-1 and -2 in the endoplasmic reticulum. It is a prime candidate to be the enzyme responsible for the pharmacological action of chiral inverted drugs. ACOT-2 activity may be important in 2-APA toxicity effects and for the regulation of mitochondrial free coenzyme A levels. These results support the idea that 2-APA drugs undergo chiral inversion via a common pathway. Copyright © 2013 Elsevier Inc. All rights reserved.

  14. Comparison of the APA-H (Westinghouse) calculations with the operational data for ZpNPP unit 3 cycles 16-19

    International Nuclear Information System (INIS)

    Abdullayev, A. M.; Gorbachenko, O. V.; Ignatchenko, A.I.; Maryokhin, S.V.; Zhukov, A. I.

    2007-01-01

    The computer simulation of ZpNPP Unit 3 (WWER-1000) Cycles 16-19 core depletion has been performed on the basis of the operational data. The changes in reactor heat rate, lead bank position and inlet temperature during the core operation have been taken into account. These calculations were performed by using Westinghouse APA-H (ALPHA/PHOENIX/ ANC-H) code system. The main objectives of the calculations were the comparison with operational data for core loading with TVS-M (Cycle 16) and transition core loading with TVS-A (Cycle 17-19). The calculation results were compared with the results of Critical boric acid concentration vs. Cycle Burnup measurements and Start up Physics Test measurements (at HZP, BOC, NoXe core conditions). Additionally, the comparison between the results of assemblies power calculation performed by ANC-H and BIPR-7A codes is presented (Authors)

  15. APA Summit on Medical Student Education Task Force on Informatics and Technology: learning about computers and applying computer technology to education and practice.

    Science.gov (United States)

    Hilty, Donald M; Hales, Deborah J; Briscoe, Greg; Benjamin, Sheldon; Boland, Robert J; Luo, John S; Chan, Carlyle H; Kennedy, Robert S; Karlinsky, Harry; Gordon, Daniel B; Yager, Joel; Yellowlees, Peter M

    2006-01-01

    This article provides a brief overview of important issues for educators regarding medical education and technology. The literature describes key concepts, prototypical technology tools, and model programs. A work group of psychiatric educators was convened three times by phone conference to discuss the literature. Findings were presented to and input was received from the 2005 Summit on Medical Student Education by APA and the American Directors of Medical Student Education in Psychiatry. Knowledge of, skills in, and attitudes toward medical informatics are important to life-long learning and modern medical practice. A needs assessment is a starting place, since student, faculty, institution, and societal factors bear consideration. Technology needs to "fit" into a curriculum in order to facilitate learning and teaching. Learning about computers and applying computer technology to education and clinical care are key steps in computer literacy for physicians.

  16. A single dose of a DNA vaccine encoding apa coencapsulated with 6,6'-trehalose dimycolate in microspheres confers long-term protection against tuberculosis in Mycobacterium bovis BCG-primed mice.

    Science.gov (United States)

    Carlétti, Dyego; Morais da Fonseca, Denise; Gembre, Ana Flávia; Masson, Ana Paula; Weijenborg Campos, Lívia; Leite, Luciana C C; Rodrigues Pires, Andréa; Lannes-Vieira, Joseli; Lopes Silva, Célio; Bonato, Vânia Luiza Deperon; Horn, Cynthia

    2013-08-01

    Mycobacterium bovis BCG prime DNA (Mycobacterium tuberculosis genes)-booster vaccinations have been shown to induce greater protection against tuberculosis (TB) than BCG alone. This heterologous prime-boost strategy is perhaps the most realistic vaccination for the future of TB infection control, especially in countries where TB is endemic. Moreover, a prime-boost regimen using biodegradable microspheres seems to be a promising immunization to stimulate a long-lasting immune response. The alanine proline antigen (Apa) is a highly immunogenic glycoprotein secreted by M. tuberculosis. This study investigated the immune protection of Apa DNA vaccine against intratracheal M. tuberculosis challenge in mice on the basis of a heterologous prime-boost regimen. BALB/c mice were subcutaneously primed with BCG and intramuscularly boosted with a single dose of plasmid carrying apa and 6,6'-trehalose dimycolate (TDM) adjuvant, coencapsulated in microspheres (BCG-APA), and were evaluated 30 and 70 days after challenge. This prime-boost strategy (BCG-APA) resulted in a significant reduction in the bacterial load in the lungs, thus leading to better preservation of the lung parenchyma, 70 days postinfection compared to BCG vaccinated mice. The profound effect of this heterologous prime-boost regimen in the experimental model supports its development as a feasible strategy for prevention of TB.

  17. ADA APA SETELAH TAX AMNESTY?

    Directory of Open Access Journals (Sweden)

    Antin Okfitasari

    2017-12-01

    Full Text Available Abstract: What is the matter After Tax Amnesty? This study analyzes the taxpayer obligation after tax amnesty and the consequences that arise if they fail to perform their obligations. The research uses descriptive qualitative approach through literature study. The research shows that there are some obligations for taxpayers to be done. Failure and misconduct in the implementation of obligations after tax amnesty, will result in consequences of sanctions, tax amnesty cancellation, and examination. Finally the relief that should be obtained taxpayers tax amnesty participants will turn into a boomerang because of it.

  18. ADA APA DENGAN KECEMASAN MATEMATIKA?

    Directory of Open Access Journals (Sweden)

    Fatrima Santri Syafri

    2017-01-01

    ABSTRACT Math anxiety is one of the factors that affect mathematics achievement. These factors can be influenced by several things, both with regard to internal factors and external factors learners. In this paper will discuss what it is about math anxiety, math anxiety indicators, impacts, and how to overcome them. Based on several studies of math anxiety, math anxiety appears that negatively affect the results of the teaching / learning achievement and influence to the mathematical abilities of learners. As a teacher or prospective teacher should also reduce math anxiety so as to reduce math anxiety owned by students. So that when giving instruction error does not occur in the delivery and may reduce students' mathematical anxiety. A teacher/tutors should understand how math anxiety indicator of students, so as to overcome math anxiety that occurs in students.at home. Keywords: math anxiety.

  19. Segregação social como externalização de conflitos ambientais: a elitização do meio ambiente na APA-Sul, Região Metropolitana de Belo Horizonte Social segregation like externalizing environmental problems: the elitization of the environment in the APA-Sul, Metropolitan Region of Belo Horizonte

    Directory of Open Access Journals (Sweden)

    Klemens Laschefski

    2008-01-01

    Full Text Available Este trabalho trata das relações de poder no conselho consultivo da APA-Sul, uma unidade de conservação localizada na Região Metropolitana de Belo Horizonte. Observa-se uma sub-representação dos setores populares, e os representantes de renda média-alta temem a favelização da região. Conseqüentemente, o conflito ambiental surge em torno da perda da qualidade ambiental nas referidas áreas, em parte associada às alternativas de habitação popular, abrindo oportunidade para discursos que justifiquem a segregação social no espaço e a elitização da paisagem em questão.This paper talks about the power relations within the consultative council of the APA-Sul, a conservation area situated in the Metropolitan Region of Belo Horizonte. There the lower-class sectors are apparently underrepresented and higher middle class representatives are concerned about the slumisation of the region. Consequently an environmental conflict arises about the loss of "environmental quality" of the area, partly associated with lower class housing, providing opportunities of discourses to justify social segregation in space and the elitization of the landscape at stake.

  20. RELAÇÕES DE TRABALHO NO TERCEIRO SETOR: UM ESTUDO EM ASSOCIAÇÕES DE PAIS E AMIGOS DOS EXCEPCIONAIS (APAEs

    Directory of Open Access Journals (Sweden)

    Amanda Burchert

    2017-03-01

    Full Text Available O objetivo deste artigo é identificar aspectos da relação de trabalho existentes em organizações do terceiro setor. A pesquisa se constituiu por uma análise qualitativa e exploratória a partir de entrevistas com gestores de APAEs. Os resultados obtidos indicam a predominância de práticas de contratação e demissão como modalidades de mediação dos vínculos, realizada em parceria com as prefeituras locais. A cedência de servidores pelo município, a ausência de profissionais qualificados na região pesquisada e a identificação dos trabalhadores com as demandas e características das instituições são desafios presentes nestas organizações. Diferentemente do aspecto majoritário do terceiro setor, nas instituições pesquisadas não há membros voluntários em virtude do receio de ações trabalhistas e reduzida articulação da comunidade. Observa-se que a diretoria tem participação efetiva nas decisões, em conjunto com a coordenação pedagógica, e há multifuncionalidade nos processos de trabalho em função do quadro de pessoal restrito.

  1. -CH2- lengthening of the internucleotide linkage in the ApA dimer can improve its conformational compatibility with its natural polynucleotide counterpart

    Science.gov (United States)

    Hanu, J.; Barvík, I.; Ruszová-Chmelová, K.; ŠtÆpánek, J.; Turpin, P.-Y.; Bok, J.; Rosenberg, I.; Petrová-Endová, M.

    2001-01-01

    The complete family of ApA phosphonate analogues with the internucleotide linkage elongated by insertion of a -CH2- group was prepared and the hybridisation and structural properties of its members in interaction with polyuridylic acid were investigated using an original 2D Raman approach. Except for the conformationally restricted ACHpA(2′3′endo-5′) modification, all of the isopolar, non-isosteric analogues form triplex-like complexes with poly(rU) at room temperature, in which two polymer strands are bound by Watson–Crick and Hoogsteen bonds to a central pseudostrand consisting of a ‘chain’ of A-dimers. For all of these dimers, the overall conformation of the triplexes was found to be similar according to their extracted Raman spectra. A simple semi-empirical model was introduced to explain the observed dependency of the efficiency of triplex formation on the adenine concentration. Apparently, for most of the modifications studied, the creation of a stable complex at room temperature requires the formation of a central pseudostrand, consisting of several adenine dimers. Molecular dynamics calculations were finally performed to interpret the differences in ‘cooperative’ behaviour between the different dimers studied. The results indicate that the exceptional properties of the ApCH2A(3′-5′) dimer could be caused by the 3D conformational compatibility of this modified linkage with the second (Hoogsteen) poly(rU) strand. PMID:11812852

  2. Qualidade da pastagem nativa obtida por diferentes métodos de amostragem e em diferentes solos na Apa do Ibirapuitã, Brasil Quality of natural pasture evaluated with different methods and soils at the Apa of Ibirapuitã, Brazil

    Directory of Open Access Journals (Sweden)

    Vicente Celestino Pires Silveira

    2005-06-01

    Full Text Available O estado do Rio Grande do Sul apresenta ecossistemas heterogêneos, devido ao grande número de tipos de solo e à variação em altitude e clima, que se reflete na diversidade da composição florística das diferentes comunidades vegetais. A Área de Proteção Ambiental do Ibirapuitã (APA do Ibirapuitã, é a única unidade de conservação federal, representante do bioma campos sulinos no Brasil. O objetivo deste trabalho foi obter informação sobre a qualidade do campo natural oriundo de três tipos de solos predominantes na APA do Ibirapuitã: Basalto superficial, Basalto profundo e Arenito obtidos por três formas de amostragem: Corte de emparelhamento, Simulação de pastejo através de coleta manual e Corte total acima da fração mantilho. Os dados foram coletados mensalmente, no período de outubro/2001 a setembro/2003. A pastagem nativa no solo de Basalto superficial apresenta forragem com qualidade nutricional superior quando comparado ao Basalto profundo e ao Arenito, comprovada pelas diferentes análises de qualidade realizadas. O método de coleta de amostras de forragem de pastagem nativa somente não influencia os resultados da análise de Fibra em Detergente Neutro. Os resultados indicam a simulação de pastejo como um método adequado de amostragem para avaliação da qualidade da pastagem nativa, devido à sua efetividade e facilidade de coleta.Heterogeneous ecosystems are found in the state of Rio Grande do Sul as a consequence of the great number of soil types and variation in altitude and climate. These conditions reflect on the great variety of flora present in the grassland communities. The Area of Environmental Protection of the Ibirapuitã (APA of Ibirapuitã is the only conservation unit under federal jurisdiction representative of the Campos bioma in Brazil. The objective of this work was to obtain information about the quality of the natural pasture on three types of soils in APA of Ibirapuitã: Superficial

  3. The Mycobacterium tuberculosis cell-surface glycoprotein apa as a potential adhesin to colonize target cells via the innate immune system pulmonary C-type lectin surfactant protein A.

    Science.gov (United States)

    Ragas, Aude; Roussel, Lucie; Puzo, Germain; Rivière, Michel

    2007-02-23

    Tuberculosis is still a major health problem, and understanding the mechanism by which Mycobacterium tuberculosis (Mtb) invades and colonizes its host target cells remains an important issue for the control of infection. The innate immune system C-type lectins (C-TLs), including the human pulmonary surfactant protein A (PSP-A), have been recently identified as determinant players in the early recognition of the invading pathogen and in mounting the host defense response. Although the antigenic lipoglycan mannosylated lipoarabinomannan is currently considered to be the major C-TL target on the mycobacterial surface, the recognition by some C-TLs of the only mycobacterial species composing the "Mtb complex" indicates that mannosylated lipoarabinomannan cannot account alone for this specificity. Thus, we searched for the mycobacterial molecules targeted by human PSP-A, focusing our attention on the Mtb surface glycoproteins. We developed an original functional proteomic approach based on a lectin blot assay using crude human bronchoalveolar lavage fluid as a source of physiological PSP-A. Combined with selective cell-surface protein extraction and mass spectrometry peptide mapping, this strategy allowed us to identify the Apa (alanine- and proline-rich antigenic) glycoprotein as new potential target for PSP-A. This result was supported by direct binding of PSP-A to purified Apa. Moreover, EDTA addition or deglycosylation of purified Apa samples completely abolished the interaction, demonstrating that the interaction is calcium- and mannose-dependent, as expected. Finally, we provide convincing evidence that Apa, formerly considered as mainly secreted, is associated with the cell wall for a sufficiently long time to aid in the attachment of PSP-A. Because, to date, Apa seems to be restricted to the Mtb complex strains, we propose that it may account for the selective recognition of those strains by PSP-A and other immune system C-TLs containing homologous functional

  4. CONFLITOS SOCIOAMBIENTAIS NA APA BORORÉ-COLÔNIA: DOS PREEXISTENTES AOS NOVOS ASSOCIADOS AO LICENCIAMENTO AMBIENTAL DO TRECHO SUL DO RODOANEL DE SÃO PAULO

    Directory of Open Access Journals (Sweden)

    José Maria Bernardelli Junior

    2017-01-01

    Full Text Available This paper addresses the social and environmental conflicts in a protected landscape of sustainable use which has faced urban expansion of high social exclusion. In this scenario of both socio and environmental vulnerability, the Protected Landscape of Borore-Colonia was created, at the same time that municipal natural parks in the interior of this APA were also created as compensatory measure for the environmental licensing of the South Part of the Metropolitan Ring Road. The research question that guided the study is: What are the interference of environmental licensing of the Metropolitan Ring Road both in existing conflicts and in the generation new conflicts in the implementation of the Municipal Natural Park Itaim in the region of Borore-Colonia Protected Landscape? The objetive of this study was to analyze the conflicts in the Protected Landscape of Borore-Colonia considering both the pre-existing conflicts to the environmental licensing of the Southern Ring Road stretch and the conflicts that emerged with the creation of the park as a compensatory measure of this licensing. This research was developed as a case study having documental analysis, semi-structured interview carried out with nine social actors, and participatory research as major sources of information. The ethnographic perspective was the selected one for the conflict analysis. As a result, both socio and environmental conflicts that took place previously and simultaneously to the environmental licensing of the South Part of the Metropolitan Ring Road were analyzed with identification of the natural and social agents involved, the major actors (including the Public Power, and their power of quotas. As a conclusion, it was perceived that the pre-existing conflicts were accentuated by the new ones resulting from the licensing and the environmental impacts of the construction of the Southern Section of the Ring Road and the conduct of the Bill of the creation of the protected

  5. FORÓFITOS PREFERENCIAIS DE ORQUÍDEAS EPÍFITAS NA APA ILHA DO COMBU, BELÉM, PARÁ, BRASIL

    Directory of Open Access Journals (Sweden)

    Tonny David Santiago Medeiros

    2014-10-01

    Full Text Available Foi avaliada a correlação da abundância de orquídeas epífitas com o tipo de casca dos forófitos e a influência do DAP sobre a abundância e a riqueza na Área de Proteção Ambiental (APA Ilha do Combu, Belém, Pará, Brasil. O estudo foi realizado em 2,85 ha, a partir da demarcação de 114 transectos de 5 m x 50 m, onde foram mensurados todos os forófitos com DAP ≥ 20 cm e anotadas as características da casca, e identificadas as orquídeas epífitas. A correlação entre o tipo de casca dos forófitos e a abundância de orquídeas foi verificada através do número de epífitas por forófitos na espécie arbórea x, e também da razão (n.° epífitas/n.° forófitos para forófitos rugosos e não-rugosos. Os diâmetros foram categorizados em classes para verificar a influência do DAP sobre a abundância e a riqueza. Trinta e cinco espécies de forófitos (73% apresentaram casca rugosa, com destaque para Hevea brasiliensis e Carapa guianensis que foram os mais amostrados (58 e 42 e mais expressivos em número de orquídeas epífitas; a razão de epífitas por forófitos foi maior em troncos com casca não-rugosa. As classes de diâmetro 2 (31,8┤ 63,7 e 3 (63,7┤ 95,5 registraram as maiores abundâncias de orquídeas epífitas. A abundância de orquídeas epífitas é influenciada pela rugosidade da casca e correlacionada aos maiores diâmetros dos forófitos. Palavras-chave: interação, hospedeiro, orquidaceae, floresta de várzea, Amazônia. DOI: http://dx.doi.org/10.18561/2179-5746/biotaamazonia.v4n3p1-4

  6. Parâmetros nutricionais da pastagem natural em diferentes tipos de solos na APA do Ibirapuitã, Rio Grande do Sul - Brasil Nutritional parameters of natural pasture in different soils at APA of Ibirapuitã, Rio Grande do Sul - Brazil

    Directory of Open Access Journals (Sweden)

    Vicente Celestino Pires Silveira

    2006-12-01

    Full Text Available O desempenho de ruminantes domésticos é influenciado por fatores intrínsecos ao animal, ao alimento e pela interação entre animal e alimento. O trabalho foi realizado na Estância do 28, pertencente à Fundação Maronna, Alegrete - RS, dentro da APA do Ibirapuitã. Para representar o fator solo, foram escolhidos os três tipos predominantes da APA do Ibirapuitã: Basalto Superficial, Basalto Profundo e Arenito. As amostras da pastagem natural foram retiradas por simulação de pastejo, através de coleta manual. Os parâmetros nutricionais avaliados foram: proteína bruta, fibra em detergente neutro e taxa de degradação da matéria seca. A forragem da pastagem natural oriunda do solo Basalto Superficial apresentou diferença significativa (PIntrinsic animal and food factors and the interaction between them influence the performance of domestic ruminants. This study was done at Estância do 28, property of the Maronna Foundation, Alegrete - RS, inside the Ibirapuitã Area of Environmental Protection. In order to represent soil as a factor, the three main soil types were chosen: Superficial Basalt, Deep Basalt and Sandy. Hand plucking methods were used to obtain samples of natural pasture. Nutritional parameters considered were crude protein, neutral detergent fiber and dry matter degradation rate. The forage from natural pasture of the Superficial Basalt presented significant difference (P<0.05 in crude protein rates over the other two types of soil, which did not differ amongst themselves. The highest rate of neutral detergent fibre (84.54% was obtained in pasture originated from Sandy soil, in relation to Superficial and Deep Basalt, with values of 74.53% and 77.98%, respectively. There was also a significant difference in the degradation rate of dry matter (P<0.05. Sandy soil pasture presented an intermediate degradation value (3.61% h-1, not differing from other soils. The forage from natural pastures present similar degradation rates

  7. Reservations about the conclusions of the interdivisional (APA Divisions 12 & 29) task force on evidence-based therapy relationships: what do we know, what don't we know?

    Science.gov (United States)

    Kazantzis, Nikolaos; Cronin, Timothy J; Norton, Peter J; Lai, Jerry; Hofmann, Stefan G

    2015-05-01

    We offer a critical and constructive appraisal of the conclusions provided by the Interdivisional (American Psychological Association [APA] Divisions 12 & 29) Task Force on Evidence-Based Therapy Relationships. We highlight problems in overlapping terminology and definitions, as well as problems in the conduct of its meta-analyses (i.e., duplication of studies between reviews, inappropriate study inclusion, and use of measures of specific constructs for the calculation of effects for multiple relationship elements). On this basis, we express reservation about the conclusions offered by the APA Task Force. This special issue explores whether there are other therapeutic relationship elements that warrant consideration and further study. We were particularly interested in those elements that showed promise based on empirical or theoretical grounds, and in each article, we asked for an account of how the case formulation would guide the methods of adaptation for each individual client, and how the element would contribute to clinically relevant changes. © 2015 Wiley Periodicals, Inc.

  8. Aberrant gonadotropin-releasing hormone receptor (GnRHR) expression and its regulation of CYP11B2 expression and aldosterone production in adrenal aldosterone-producing adenoma (APA).

    Science.gov (United States)

    Nakamura, Yasuhiro; Hattangady, Namita G; Ye, Ping; Satoh, Fumitoshi; Morimoto, Ryo; Ito-Saito, Takako; Sugawara, Akira; Ohba, Koji; Takahashi, Kazuhiro; Rainey, William E; Sasano, Hironobu

    2014-03-25

    Aberrant expression of gonadotropin-releasing hormone receptor (GnRHR) has been reported in human adrenal tissues including aldosterone-producing adenoma (APA). However, the details of its expression and functional role in adrenals are still not clear. In this study, quantitative RT-PCR analysis revealed the mean level of GnRHR mRNA was significantly higher in APAs than in human normal adrenal (NA) (P=0.004). GnRHR protein expression was detected in human NA and neoplastic adrenal tissues. In H295R cells transfected with GnRHR, treatment with GnRH resulted in a concentration-dependent increase in CYP11B2 reporter activity. Chronic activation of GnRHR with GnRH (100nM), in a cell line with doxycycline-inducible GnRHR (H295R-TR/GnRHR), increased CYP11B2 expression and aldosterone production. These agonistic effects were inhibited by blockers for the calcium signaling pathway, KN93 and calmidazolium. These results suggest GnRH, through heterotopic expression of its receptor, may be a potential regulator of CYP11B2 expression levels in some cases of APA. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  9. GENÉTICA DA CONSERVAÇÃO DE Cabralea canjerana (Vell. Mart. (Meliaceae EM FRAGMENTOS FLORESTAIS DE MATA ATLÂNTICA NA APA FERNÃO DIAS

    Directory of Open Access Journals (Sweden)

    Arthur Tavares de Oliveira Melo

    2015-04-01

    Full Text Available A Mata Atlântica é o bioma brasileiro mais severamente afetado pela fragmentação ambiental. A análise da estruturação da diversidade genética, assim como de características demográficas e quantitativas, permite inferir parâmetros populacionais importantes para os programas de conservação de espécies ameaçadas. Cabralea canjerana ssp. canjerana (Meliaceae é uma espécie arbórea dioica considerada modelo para estudos de conservação da Mata Atlântica. Cento e oitenta e três indivíduos de oito subpopulações de C. canjerana foram coletados em fragmentos florestais na Área de Proteção Ambiental (APA Fernão Dias, no Sul do Estado de Minas Gerais, Brasil. Utilizando marcadores microssatélites, a diversidade genética foi estimada e contrastada com medidas quantitativas e medidas geográficas dessas oito subpopulações. Elevados níveis de diversidade genética foram encontrados. Uma porção pequena, porém significativa, da variância genética total está estruturada entre as populações (θ = 0,053, que foram estruturadas em dois grupos distintos. As estimativas dos níveis de diversidade genética nas populações localizadas acima de 1.800 m de altitude foram maiores, corroborando a importância dessas populações na manutenção da diversidade genética. A densidade populacional observada também foi maior nos fragmentos de maior altitude (r = 0,849; p-valor = 0,007. Não houve correlação significativa entre as variáveis fenotípicas (altura dos indivíduos e diâmetro a 1,50 m acima do solo e as medidas de diversidade genética. Esforços conservacionistas para que aumentem o fluxo gênico entre esses fragmentos florestais devem ser estimulados, principalmente entre os fragmentos de baixa altitude e os fragmentos de elevada altitude. É comprovado que populações situadas em elevadas altitudes possuem maior número de indivíduos por hectare e, portanto, maiores índices de diversidade genética. Essas

  10. Predação oportunista de Artibeus planirostris (Spix, 1823 e Carollia perspicillata (Linnaeus, 1758 (Chiroptera, Phyllostomidae por marsupiais e anuro na APA do Rio Curiaú, Amapá, Brasil Opportunistic predation of Artibeus planirostris (Spix, 1823 and Carollia perspicillata (Linnaeus, 1758 (Chiroptera, Phyllostomidae by marsupials and anuran in the APA do Rio Curiaú, Amapá State, Brazil

    Directory of Open Access Journals (Sweden)

    Isai Jorge de Castro

    2011-03-01

    Full Text Available Durante estudos com morcegos em floresta de várzea na APA do Rio Curiaú, Amapá, Brasil, observamos três casos de predações oportunistas de morcegos frugívoros capturados em redes de neblina. Duas destas predações ocorreram por marsupiais e uma por anuro. Artibeus planirostris (Spix, 1823 (Chiroptera, Phyllostomidae foi predado por Didelphis marsupialis Linnaeus, 1758 e Philander opossum (Linnaeus, 1758 (Didelphimorphia, Didelphidae. Carollia perspicillata (Linnaeus, 1758 (Chiroptera, Phyllostomidae foi predado por Leptodactylus pentadactylus (Laurenti, 1768 (Anura, Leptodactylidae. A vocalização dos morcegos provavelmente atraiu os marsupiais para a rede, onde estes os predaram aproveitando que estavam presos. Este tipo de interação pode ocorrer naturalmente, no entanto, com maior dificuldade de registro.We observed three occasional predations of bats captured in mist nets by marsupials and a frog during studies in a várzea forest in the Amapá state. Artibeus planirostris (Spix, 1823 (Chiroptera, Phyllostomidae was preyed upon by Didelphis marsupialis Linnaeus, 1758 and Philander opossum (Linnaeus, 1758 (Didelphimorphia, Didelphidae. Carollia perspicillata (Linnaeus, 1758 (Chiroptera, Phyllostomidae was preyed on by Leptodactylus pentadactylus (Laurenti, 1768 (Anura, Leptodactylidae. The bats vocalizations probably attracted the marsupials and a frog to the mist nets where they preyed. This interaction form can occur naturally, however, are more difficult to observed.

  11. Association of vitamin D receptor BsmI, TaqI, FokI, and ApaI polymorphisms with susceptibility of chronic periodontitis: A systematic review and meta-analysis based on 38 case -control studies.

    Science.gov (United States)

    Mashhadiabbas, Fatemeh; Neamatzadeh, Hossein; Nasiri, Rezvan; Foroughi, Elnaz; Farahnak, Soudabeh; Piroozmand, Parisa; Mazaheri, Mahta; Zare-Shehneh, Masoud

    2018-01-01

    There has been increasing interest in the study of the association between Vitamin D receptor (VDR) gene polymorphisms and risk of chronic periodontitis. However, the results remain inconclusive. To better understand the roles of VDR polymorphisms (BsmI, TaqI, FokI, and ApaI) in chronic periodontitis susceptibility, we conducted this systematic review and meta-analysis. The PubMed, Google Scholar, and Web of Science database were systemically searched to determine all the eligible studies about VDR polymorphisms and risk of chronic periodontitis up to April 2017. Odds ratio (OR) and 95% confidence interval (CI) were used to evaluate the associations between VDR polymorphisms and chronic periodontitis risk. All the statistical analyses were performed by Comprehensive Meta-Analysis. All P values were two-tailed with a significant level at 0.05. Finally, a total of 38 case-control studies in 19 publications were identified which met our inclusion criteria. There are ten studies with 866 chronic periodontitis cases and 786 controls for BsmI, 16 studies with 1570 chronic periodontitis cases and 1676 controls for TaqI, five studies with 374 chronic periodontitis cases and 382 controls for FokI, and seven studies with 632 chronic periodontitis cases and 604 controls for ApaI. Overall, no significant association was observed between VDR gene BsmI, TaqI, FokI, and ApaI polymorphisms and risk of chronic periodontitis in any genetic model. Subgroup analysis stratified by ethnicity suggested a significant association between BsmI polymorphism and chronic periodontitis risk in the Caucasian subgroup under allele model (A vs. G: OR = 1.747, 95% CI = 1.099-2.778, P = 0.018). Further, no significant associations were observed when stratified by Hardy-Weinberg equilibrium status for BsmI, TaqI, and ApaI. Our results suggest that BsmI, TaqI, FokI, and ApaI polymorphisms in the VDR gene might not be associated with risk of chronic periodontitis in overall population.

  12. BsmI, ApaI and TaqI Polymorphisms in the Vitamin D Receptor Gene (VDR and Association with Lumbar Spine Pathologies: An Italian Case-Control Study.

    Directory of Open Access Journals (Sweden)

    Alessandra Colombini

    Full Text Available Three adjacent single nucleotide polymorphisms of the vitamin D receptor gene (VDR BsmI (rs1544410, ApaI (rs7975232, and TaqI (rs731236 are commonly studied in several pathologies. We aimed to evaluate the distribution of VDR BsmI, ApaI, and TaqI allele, genotype, and haplotype frequencies in an Italian cohort of 266 patients with lumbar spine disorders assessed by Magnetic Resonance Imaging and 252 asymptomatic controls. The exposure to putative risk factors was evaluated by a questionnaire. Polymorphisms were detected by PCR-RFLP and TaqMan® SNP Genotyping Assay. The results were statistically adjusted for the identified conventional risk factors. The three SNPs were in linkage disequilibrium. For all cases BbAaTT was a 3-fold risk factor OR = 3.38, whereas bbAATT (OR = 0.22, and bbaaTT (OR = 0.47 genotypes were found to be protective. Specifically, for patients affected by disc herniation only (n = 88 and all lumbar pathologies excluding stenosis and/or spondylolistesis (n = 215 B allele, Bb, Aa, and BbAaTT genotypes were risky, whereas b allele, bb, aa, and bbaaTT genotypes were protective. In patients affected by osteochondrosis with or without disc hernation (n = 50, T allele, Aa, and bbAaTT genotypes were risky, whereas t allele, AA, tt genotypes were protective. In patients affected by stenosis and/or spondylolistesis (n = 51 no significant associations were found. This is the first study showing an association of the three genetic VDR variants BsmI, ApaI, and TaqI and lumbar spine pathologies. Our study contributes to delineate genetic risk factors for specific subgroups of patients with lumbar spine pathologies highlighting the importance of haplotype analysis, and of detailed clinical evaluation of the patients for identification of genetic biomarkers.

  13. Análise quantitativa do processo de erosão/deposição nas falésias da APA Tambaba e sua ocupação nos limites da APP

    Directory of Open Access Journals (Sweden)

    Thaís Regina Benevides Trigueiro Aranha

    2013-08-01

    Full Text Available O litoral brasileiro é banhado pelo Oceano Atlântico e composto por diversas paisagens ao longo da costa. Entre elas encontram-se as falésias, que, por sua beleza, atraem a exploração turística o que, muitas vezes, compromete seu equilíbrio. Com a finalidade de proteger o meio ambiente das ações antrópicas, o poder público vem criando áreas para preservar e/ou conservar o meio ambiente, entre elas existem as APA e as APP. O objetivo do presente trabalho foi analisar a variabilidade espaço-temporal da linha de ruptura do relevo, na borda das falésias da APA Tambaba, entre os anos de 1985 e 2012; e identificar a existência de edificações dentro da APP no ano de 2012. Para tanto, foram utilizadas imagens do satélite Quickbird de 2012, do satélite IKONOS II de 2005 e fotos aéreas de 1985 para delimitação das linhas das falésias; o DSAS, que é uma extensão gratuita do ArcGIS, para obtenção de taxas de variação da linha de ruptura do relevo; e o software ArcGIS para delimitação e análise das APP. Como resultados, foram identificadas variações no movimento das linhas estudadas, tanto para erosão como para deposição nas falésias da APA Tambaba. No maior trecho da APA obteve-se uma média de -0,17m/ano para erosão e de 0,49m/ano para deposição, já no menor trecho a média de erosão foi -0,38m/ano e de deposição 0,14m/ano. Foi comprovada a existência de edificações irregulares correspondente a 22.818,91 m², o que equivale a aproximadamente 3% da área total da APP.

  14. Valoração contingente da Área de Proteção Ambiental (APA São José - MG: um estudo de caso

    Directory of Open Access Journals (Sweden)

    Jader Fernandes Cirino

    2008-09-01

    Full Text Available A Área de Proteção Ambiental (APA São José - MG apresenta um rico patrimônio natural e histórico. Apesar de tal fato e de ser uma área de proteção desde 1981, a APA São José vem sofrendo com degradações ambientais. Dentro desse contexto, emergiu a questão de se valorar a APA São José com o objetivo de fornecer subsídios para a elaboração e consecução de políticas públicas e de projetos públicos e privados de conservação ou exploração sustentável do referido ativo. Como método de valoração, utilizou-se a valoração contingente, por meio da abordagem de Hanemann (1984 e o método de bootstrapping, para obter uma disposição a pagar (DAP mensal por família dos cinco municípios que compreendem a APA São José, de R$ 22,88, com um desvio padrão relativamente baixo de R$ 3,25. Quanto à confiabilidade da medida estimada, destaca-se a preocupação do presente trabalho em adotar procedimentos visando evitar ou minimizar os viéses que geralmente ocorrem em pesquisas de valoração ambiental.The São José Environmental Protection Area (EPA in the State of Minas Gerais has a rich natural and historical patrimony. However, in spite of its value and of being a protection area since 1981, it has now suffering several degradations. In that sense, the major objective of this work is to value São José EPA with the purpose of supplying subsidies for the elaboration and attainment of public and private projects of preservation or sustainable exploration of the referred asset, as well as for public policy directed to its administration. As valuation method, it was used the contingent valuation through the approach of Hanemann (1984 and the bootstrapping method to obtain a monthly willingness-to-pay (WTP per family of the municipal districts that compose São José EPA of R$22,88, with a relatively low standard-error, R$3,25. As for the reliability of the estimate measure, stands out the concern of the present work in

  15. Scale-up from shake flasks to bioreactor, based on power input and Streptomyces lividans morphology, for the production of recombinant APA (45/47 kDa protein) from Mycobacterium tuberculosis.

    Science.gov (United States)

    Gamboa-Suasnavart, Ramsés A; Marín-Palacio, Luz D; Martínez-Sotelo, José A; Espitia, Clara; Servín-González, Luis; Valdez-Cruz, Norma A; Trujillo-Roldán, Mauricio A

    2013-08-01

    Culture conditions in shake flasks affect filamentous Streptomyces lividans morphology, as well the productivity and O-mannosylation of recombinant Ala-Pro-rich O-glycoprotein (known as the 45/47 kDa or APA antigen) from Mycobacterium tuberculosis. In order to scale up from previous reported shake flasks to bioreactor, data from the literature on the effect of agitation on morphology of Streptomyces strains were used to obtain gassed volumetric power input values that can be used to obtain a morphology of S. lividans in bioreactor similar to the morphology previously reported in coiled/baffled shake flasks by our group. Morphology of S. lividans was successfully scaled-up, obtaining similar mycelial sizes in both scales with diameters of 0.21 ± 0.09 mm in baffled and coiled shake flasks, and 0.15 ± 0.01 mm in the bioreactor. Moreover, the specific growth rate was successfully scaled up (0.09 ± 0.02 and 0.12 ± 0.01 h(-1), for bioreactors and flasks, respectively), and the recombinant protein productivity measured by densitometry, as well. More interestingly, the quality of the recombinant glycoprotein measured as the amount of mannoses attached to the C-terminal of APA was also scaled- up; with up to five mannose residues in cultures carried out in shake flasks; and six in the bioreactor. However, final biomass concentration was not similar, indicating that although the process can be scaled-up using the power input, others factors like oxygen transfer rate, tip speed or energy dissipation/circulation function can be an influence on bacterial metabolism.

  16. Ada Apa Dengan SAP (AADS Akrual?

    Directory of Open Access Journals (Sweden)

    Eka Findi Tresnawati

    2013-08-01

    Full Text Available This article provides anoverview regarding SAP accrual-based and its problems. It compares information content of PP 24/2005’s cash toward accrual and PP 71/2010’s accrual-based toshow the urgency of accrual-based financial reporting requirements. The analysis borrows Abeysekara’s accounting imperialism. Discussion also involves empirical evidence and evaluation of accrual-based implementation probability in Sumenep Regency. Findings show that accrual-based information is not an urgent need and tends to be difficult to be implemented. Reflecting the evidence in Sumenep, local governments are faced with the need of human resources, the question of the use-fulness of accrual information, and technical difficulties on implementation.

  17. POLA PENDIDIKAN KITA, APA YANG SALAH

    Directory of Open Access Journals (Sweden)

    Alpiyanto Alpiyanto

    2012-06-01

    Full Text Available AbstractIdeals to the intellectual life of the nation by order of value as thefoundation of ethics and moral domains of intelligence and skill has beendisoriented. It can be seen from the culture of corruption that stillplagued the country, beating punishment of journalists that was hitby students of SMAN 6 Jakarta, clashes among students in Lampung, clashes among residents in different regions and the church bombing inSolo. Therefore, this study wanted to find out what went wrong to educationthat has been implemented so far. This study is a case study of thepatterns which are applied during this study. The study results showed that theeducation that has been implemented so far seems to be concerned with the logicrather than feelings (language of heart so it is suggested that it is important to educate the heart rather than logic.Keywords: educate, by heart, logic

  18. APA Citation Style (6th Edition)

    OpenAIRE

    2010-01-01

    ARP-AA-12-003 Acquisition Research Handbook Series This handbook is one of a series of four produced for the Acquisition Research Program (ARP) at the Naval Postgraduate School. The purpose of the ARP Handbook Series is to provide helpful information in a user-friendly format to assist graduate students and others in improving their research and writing skills.

  19. Citing Legal Material in APA Journals.

    Science.gov (United States)

    Osborne, Allan G., Jr.

    1992-01-01

    Guidelines are offered to authors on the correct citation format for legal references, including statutes and regulations, court decisions, and law review articles. Standards are based on those published by the Harvard Law Review Association and the American Psychological Association. (DB)

  20. Aspectos do licenciamento ambiental da carcinicultura na APA do Delta do Parnaíba Aspects of environmental licensing for carciniculture in EPA of the Delta of Parnaíba River

    Directory of Open Access Journals (Sweden)

    Hamilton Gondim de Alencar Araripe

    2006-12-01

    Full Text Available O presente trabalho tem como foco uma análise do valor do licenciamento ambiental da carcinicultura na APA do Delta do Parnaíba. Realizou-se visitas técnicas a todos empreendimentos instalados até o primeiro semestre de 2004, levantou-se a legislação pertinente, avaliou-se estudos ambientais e relatórios de vistorias técnicas realizadas pelo IBAMA. Concluiu-se que o enquadramento feito pelo IBAMA no processo de licenciamento do que seja área de preservação permanente (APP no manguezal é o ponto crítico para a atividade de carcinicultura.The present research examines the environmental matter in the Environmental Protection Area (EPA of the Delta of the Parnaíba River, focusing on the ambient licensing value. Technical visits to all companies installed in the area until the first semester of 2004 and non-structured interviews were carried out; the existing legislation was raised; and the environmental studies and reports of technical inspections performed by IBAMA were evaluated. The conclusion was that the adjustment made by IBAMA in the ambient licensing process of what is an Area of Permanent Preservation (APP in the mangrove is the critical point to the carciniculture activity.

  1. Análise da riqueza da fauna de Braconidae (Hymenoptera, Ichneumonoidea em remanescentes naturais da Área de Proteção Ambiental (APA de Descalvado, SP

    Directory of Open Access Journals (Sweden)

    Cirelli Kátia Resende Netto

    2003-01-01

    Full Text Available Analysis of the Braconidae (Hymenoptera: Ichneumonoidea fauna richness in natural remnants of the Área de Proteção Ambiental (APA of Descalvado, SP. A survey of the Braconidae fauna on fragmentary natural environments at northeast São Paulo State was conducted using Malaise traps installed in five sites of Área de Proteção Ambiental of Descalvado. A total of 2,262 specimens, representing 22 subfamilies and 94 genera, was sampled throughout a period of sixteen months (from May, 1999 to August, 2000. Biological data were obtained from current literature and behavior patterns of host utilization for the studied fauna, mainly Braconidae which have been successful in control of agricultural insect pests. Statistical analyses indicated that the asymptote of the genera richness has been approached using this sampling method. This is the most complete survey yet available from natural fragmentary areas of the Descalvado Braconidae fauna. Patterns of distribution and richness of the Braconidae genera were established. Cluster Analysis was adopted taking as attribute the number of Braconidae genera.

  2. A apropriação social do espaço como fator de urbanização na dinâmica das sociedades modernas: o caso da APA da Fazendinha

    Directory of Open Access Journals (Sweden)

    Olavo Fagundes da Silva

    2010-07-01

    Full Text Available Normal 0 21 false false false MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabela normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} O trabalho faz uma reflexão sobre a singularidade da urbanização a partir da apropriação social dos espaços urbanos no mundo moderno, toma-se como referencia o processo de apropriação social e urbanização na Área de Proteção Ambiental da Fazendinha situada entre os municípios de Macapá e Santana no estado do Amapá. Procurou-se analisar as nuances do processo de urbanização que mescla a instalação de elementos da dinâmica capitalista nas cidades com as transformações engendradas pelos menos abastados. Esse aparente choque entre o moderno e objetos que marcam os traços culturais do povo da região Amazônica em suas cidades médias e grandes está estampado em arranjos espaciais que configuram o urbano como resultado da apropriação social do espaço. Estes arranjos foram objeto do estudo da apropriação social na APA da Fazendinha realizado em incursões ao local em 2007 através de entrevistas e mapeamento físico-ambiental utilizando aparelho receptor GPS e técnicas de geoprocessamento. O estudo constatou-se que a apropriação social da APA da Fazendinha resultou no processo de urbanização da unidade de conservação por uma população de baixa renda, que imprimiu no local, traços de suas características culturais, como a construção de palafitas na margem do Igarapé da Fortaleza e uma dinamização econômica baseada na informalidade, mas fortemente ligada a atividades tradicionais da região como a pesca e a construção de pequenas

  3. FECUNDIDADE E TIPO DE DESOVA DO PORAQUÊ, Electrophorus electricus, (LINNAEUS, 1766 (OSTEICHTHYIES: GYMNOTIFORMES: GYMNOTIDAE DA ÁREA DE PROTEÇÃO AMBIENTAL – APA – DO RIO CURIAÚ, MACAPÁ-AP.

    Directory of Open Access Journals (Sweden)

    Júlio César Sá-Oliveira

    2012-07-01

    Full Text Available O presente estudo objetivou estimar a fecundidade e o tipo de desova do peixe-elétrico Electrophorus electricus da Área de Proteção Ambiental - APA do Rio Curiaú, Macapá-Amapá. As análises foram realizadas a partir de 96 exemplares do peixe coletados no período de março de 2006 a fevereiro de 2007. Análises do ciclo anual de estádios de maturação gonadal, exames macro e microscópico das gônadas, verificação dos diâmetros e contagens dos ovócitos foram realizadas. O número de ovócitos relacionados a uma dimensão corpórea (comprimento total e ao Peso Total (g foi ajustado a uma regressão linear. Os resultados revelaram que a desova é do tipo total e sincrônico, ocorrendo no início do inverno (janeiro-fevereiro. A fecundidade, estimada variou de 1.730 a 3.063 ovócitos vitelogênicos. A fecundidade mostrou correlação positiva com o comprimento total e peso total do corpo, aumentando proporcionalmente com o tamanho de Electrophorus electricus.   Palavras-chave: biologia reprodutiva, Amapá, estádios de maturação gonadal, Brasil.   DOI: http://dx.doi.org/10.18561/2179-5746/biotaamazonia.v2n1p32-36

  4. Uso do grau de preferência alimentar para a caracterização da alimentação de peixes na APA de São Pedro e Analândia - DOI: 10.4025/actascibiolsci.v27i3.1337 The use of feeding preference degree to characterize feeding habits of fishes at APA in São Pedro and Analândia - DOI: 10.4025/actascibiolsci.v27i3.1337

    Directory of Open Access Journals (Sweden)

    Leandro Muller Gomiero

    2005-03-01

    Full Text Available O trabalho caracterizou a alimentação de quatro espécies de peixes em duas bacias da Área de Proteção Ambiental de São Pedro e Analândia, área central do Estado de São Paulo. O Grau de Preferência Alimentar (GPA foi utilizado para mostrar a importância de cada item alimentar para as espécies de peixes em cada bacia. A alimentação das duas espécies de lambaris foi muito variada, sendo que os itens insetos alóctones, autóctones e material vegetal foram muito importantes, caracterizando-a como onivoria. O bagre (Rhamdia quelen alimentou-se principalmente de insetos na bacia do Jacaré-pepira e também de peixes na bacia do Corumbataí. O cascudo, Hypostomus strigaticeps, ingeriu material vegetal autóctone e sedimentos em ambas baciasWe studied feeding habits of four fish species in two watershed at APA - Área de Proteção Ambiental (Area of Environmental Protection in São Pedro and Analândia, State of São Paulo, southeastern Brazil. Feeding Preference Degree (FPD was used to demonstrate the importance of each food item for the species of both basins. Feeding habits of both species of “lambari” was variable. The allochtonous items such as insects, autochtonous items, and vegetal material were very important, characterizing omnivory. The “bagre” (Rhamdia quelen fed mainly on insects at the Jacaré-pepira Basin and also on fishes at the Corumbataí basin. The “cascudo” Hypostomus strigaticeps ingested autochtonous vegetal material and sediments at both basins

  5. INFLUÊNCIA DOS FATORES GEOLÓGICOS, GEOMORFOLÓGICOS E ANTRÓPICOS DA PRODUÇÃO DE FLUXO DE BASE EM PEQUENAS BACIAS HIDROGRÁFICAS NA APA CACHOEIRA DAS ANDORINHAS, OURO PRETO (MG

    Directory of Open Access Journals (Sweden)

    Josefa Clara Monteiro

    2014-08-01

    Full Text Available Neste trabalho objetivou-se estabelecer a influência da geologia, geomorfologia e uso e ocupação do solo no potencial hídrico de pequenas bacias hidrográficas situadas na Área de Proteção Ambiental Estadual da Cachoeira das Andorinhas (APA/CA. Foram selecionados três pares de bacias, cada par com condições geológicas e geomorfológicas semelhantes, mas com graus distintos de interferência antrópica. Utilizando-se dados de chuva e vazão, obtidos durante um ano hidrológico, estabeleceram-se os regimes pluviométricos e fluviométricos e determinaram-se alguns parâmetros hidrológicos, como o fluxo de base pela técnica smoothed mínima e o coeficiente de recessão (α pela técnica matching strip. A análise conjugada destes parâmetros, de índices morfométricos e de dados físico-químicos das águas indicam que as bacias em áreas de relevo mais suave tendem a apresentar menores coeficientes de recessão e maiores volumes de fluxo de base. Portanto, nestas áreas o potencial hídrico é maior, já que a vazão das drenagens se mantém por mais tempo na estação seca. O relevo mais suave, com solo mais espesso e maior tempo de trânsito das águas subterrâneas, também justificam as águas mais redutoras e com maiores condutividades elétricas. Os dados também sugerem que as bacias da área com maiores proporções de florestas tendem a apresentar menores fluxos de base por conta das maiores taxas de evapotranspiração. Os métodos aplicados se mostraram adequados para caracterizar o regime hídrico de pequenas bacias hidrográficas e podem ser importantes para a gestão de recursos hídricos.

  6. Ambulatório de genética médica na Apae: experiência no ensino médico de graduação

    Directory of Open Access Journals (Sweden)

    Débora Gusmão Melo

    Full Text Available Este trabalho relata uma experiência de ensino cujo objetivo foi oferecer formação significativa e integradora na área de genética médica aos graduandos de medicina do Centro Universitário Barão de Mauá. Para isto, em 2005, foi estruturado um ambulatório de genética médica na Associação de Pais e Amigos dos Excepcionais (Apae do município de Jardinópolis (SP, como parte do estágio de internato em Saúde Coletiva e Medicina da Família e Comunidade, realizado nos serviços de saúde desse município. Desde então, os estudantes do sexto ano do curso médico avaliaram 140 pacientes, estabelecendo o grau de comprometimento intelectual, a etiologia da deficiência mental e oferecendo aconselhamento genético não-diretivo às famílias, sob orientação dos professores. A diversificação do cenário de ensino e aprendizagem aproximou os alunos da realidade dos pacientes com deficiência mental no País. Além disto, os estudantes puderam se apropriar de alguns fundamentos teóricos da genética médica a partir da constatação de suas implicações na prática clínica, tornando a aprendizagem significativa. Com esta experiência espera-se ter contribuído para a formação de médicos mais competentes na área da genética médica e saúde coletiva, e dispostos a trabalhar de forma integrada e integradora com a comunidade.

  7. Trajetórias do Jaguary - unidades de conservação, percepção ambiental e turismo: um estudo na APA do Sistema Cantareira, São Paulo Trajectories of the Jaguary conservation areas, environmental perception and tourism a study in the Cantareira system environmental protected area, São Paulo

    Directory of Open Access Journals (Sweden)

    João Luiz Hoeffel

    2008-06-01

    Full Text Available A Área de Proteção Ambiental Cantareira (APA Cantareira tem passado por diversas transformações, associadas à expansão urbana e turística. Observa-se, nesta pesquisa, que os grupos sociais atuantes nessa região apresentam diferentes perspectivas sobre meio ambiente e desenvolvimento, o que tem gerado conflitos de uso pelos recursos naturais, e que não existem planos regionais que apontem soluções efetivas para os problemas socioambientais em curso.The Cantareira Environmentally Protected Area (EPA Cantareira has been undergoing several transformations due to the growth of urban areas and tourism. The present piece of research points out that the active social groups in this region have different perspectives to the environment and development. This leads to conflicts in the use of natural resources and there are no regional plans suggesting effective solutions for the identified social and environmental problems.

  8. Forging ahead: the 2003 APA Division 30 definition of hypnosis.

    Science.gov (United States)

    Green, Joseph P; Barabasz, Arreed F; Barrett, Deirdre; Montgomery, Guy H

    2005-07-01

    The article describes the rationale for and the process of developing a new definition of hypnosis by the Society of Psychological Hypnosis, Division 30 of the American Psychological Association. Both theoretical and practical implications led to the production of the definition, which is targeted toward informing clinicians, researchers, and the lay public alike. The definition is presented at the conclusion of the article.

  9. Guía para citar y referenciar. Estilo APA

    OpenAIRE

    Ruiz-de-Luzuriaga-Peña, Manuel

    2017-01-01

    This guide has been written for use by students of the Public University of Navarra in the writing of their academic works, following the guidelines of the "Manual de publicaciones de la American Psychological Association".

  10. Violence against Teachers: Case Studies from the APA Task Force

    Science.gov (United States)

    Reddy, Linda A.; Espelage, Dorothy; McMahon, Susan D.; Anderman, Eric M.; Lane, Kathleen Lynne; Brown, Veda Evanell; Reynolds, Cecil R.; Jones, Abraham; Kanrich, Jaclyn

    2013-01-01

    Violence directed toward teachers has been understudied despite significant media and empirical investigation on school violence, such as student-to-student victimization and bullying. To date, there are relatively few published studies scattered across many countries. To address this void, the American Psychological Association, in collaboration…

  11. Personal dimensions of identity and empirical research in APA journals.

    Science.gov (United States)

    Munley, Patrick H; Anderson, Mary Z; Baines, Tonita C; Borgman, Amy L; Briggs, Denise; Dolan, James P; Koyama, Miki

    2002-11-01

    This study reviewed 402 empirical research papers published during 1999 in 9 American Psychological Association journals from the perspective of the Personal Dimensions of Identity (PDI) model. Descriptions of participants were reviewed to determine whether researchers reported information concerning Dimensions A, B, and C of the PDI model. PDI A and B Dimensions of age, gender, education, and geographic location were reported with the highest frequency: 88.56%, 89.30%, 78.50%, and 73.88%, respectively, whereas race/ethnicity was reported with moderate frequency, 60.70%. The remaining PDI A Dimensions of language, physical disability, sexual orientation, and social class, and the remaining B Dimensions of citizenship status, employment status, income, marital status, military experience, occupation, and religion, were reported in relatively low percentages of studies.

  12. Asphalt mix characterization using dynamic modulus and APA testing.

    Science.gov (United States)

    2005-11-01

    final report summarizes two research efforts related to asphalt mix characterization: dynamic modulus and Asphalt Pavement Analyzer testing. One phase of the research consisted of a laboratory-based evaluation of dynamic modulus of Oregon dense-grade...

  13. Calcium carboorthovanadate - a new compound with the apa

    International Nuclear Information System (INIS)

    Slobodin, B.V.; Dmitrieva, O.I.; Fotiev, A.A.

    1977-01-01

    Data on calcium carboorthovanadate, Ca 10 (VO 4 ) 6 CO 3 , a new compound with an appatite structure based on calcium orthovanadate, are reported. The synthesis has been conducted in a stoichiometric mixture of finely ground calcium carbonate and calcium orthovanadate. It is found that calcium carboorthovanadate belongs to the hexagonal syngony and has an apatite structure. An analysis of the infrared spectra of initial compounds and calcium carboorthovanadate confirmed the presence of carbonate (CO 3 ) 2- and orthovanadate (VO 4 ) 3 groupings in the latter. On heating in air, beginning with 450 deg C calcium carboorthovanadate decomposes at a slow rate into calcium oxide, calcium orthovanadate, and carbon dioxide

  14. How to Use Current Medical Literature and APA Format Style.

    Science.gov (United States)

    Peek, Robin

    Directives and guidance in obtaining current medical literature are provided in this publication with special emphasis given to locating material in the Portland, Oregon area. The uses and types of periodical indexes are identified and periodical index citation examples are indicated. Explanations are offered on: (1) how to conduct an effective…

  15. Critical Pedagogy and APA: A Resonant (and Timely) Interdisciplinary Blend.

    Science.gov (United States)

    Connolly, Maureen; Harvey, William J

    2018-04-12

    Critical pedagogy owes much of its emergence, development, and ongoing relevance to the work of Paulo Freire whose legacy remains relevant for a next generation of scholars who seek to explore issues of inclusion, oppression, social justice, and authentic expression. An interdisciplinary dialogue between critical pedagogy and adapted physical activity is timely, appropriate, and should focus on complex profiles of neurodiversity, mental illness, and mental health, with emphasis on pedagogic practices of practitioners in service delivery and teacher educators who prepare them for professional practice. A case-based scenario approach is used to present practitioner and teacher educator practices. Concrete examples are provided for analyzing and understanding deeper issues and challenges related to neurodiversity in a variety of embodied dimensions in educational and activity contexts. We work with Szostak's approach to interdisciplinary research and model an analysis strategy that integrates and applies the methodological features of interdisciplinarity, adapted physical activity, and critical pedagogy.

  16. Preparing Special Education Research Articles in APA Style.

    Science.gov (United States)

    Algozzine, Bob; Spooner, Fred; Karvonen, Meagan

    2002-01-01

    This article addresses key considerations in preparing special education research articles for submission to professional journals in which the preferred style guide is the "Publication Manual of the American Psychological Association." The guidelines are drawn from special education literature, from editors, and from authors experienced in…

  17. Putting the APA "Publication Manual" in Context. Commentary.

    Science.gov (United States)

    Russo, Nancy Felipe

    1999-01-01

    Explores feminist criticism of the "Publications Manual" of the American Psychological Association and the ways in which feminist researchers have negotiated changes in the language of this style guide. (SLD)

  18. Writing in APA Style: Faculty Perspectives of Competence and Importance

    Science.gov (United States)

    Landrum, R. Eric

    2013-01-01

    A US sample (N = 360) of psychology educators assessed 73 writing skills and competencies with regard to (a) the importance of each and (b) the typical performance of the top half of local psychology majors. An analysis of gap scores yielded results showing that specific skills, such as supporting claims with citations and proofreading ability,…

  19. Tipologia de frutos e síndromes de dispersão de um fragmento de Cerrado sensu stricto da APA do Gama e Cabeça de Veado e montagem de Coleção Didática de frutos – Carpoteca - doi: 10.5102/ucs.v9i1.1385

    Directory of Open Access Journals (Sweden)

    Carolina Cátia Schaffer

    2011-07-01

    Full Text Available Com o objetivo de realizar um levantamento tipológico de frutos e síndromes de dispersão de um fragmento de Cerrado sensu stricto, e montar uma carpoteca, o presente trabalho partiu da premissa de que o Cerrado apresenta alta diversidade de frutos e estratégias de dispersão. Os frutos foram coletados na APA do Gama e Cabeça de Veado (Brasília-DF, entre os meses de agosto de 2009 a maio de 2010. A coleta foi feita pelo método de caminhamento com busca ativa por espécimes maduros. Os frutos foram classificados de acordo com a consistência, deiscência e as síndromes de dispersão, e divididos em grupos, tipos e subtipos. Foram coletados 79 frutos, sendo 70 frutos simples, 7 múltiplos e 2 compostos; 43 deiscentes e 36 indeiscentes; 53 secos e 26 carnosos. Anemocoria foi a síndrome de dispersão prevalecente. A diversidade florística encontrada no fragmento garantiu elevada variabilidade de formas de frutos para a carpoteca.

  20. Some polite applause for the 2003 APA Division 30 definition of hypnosis.

    Science.gov (United States)

    Woody, Erik; Sadler, Pamela

    The authors argue that the new definition of hypnosis by Division 30 of the American Psychological Association contains questionable information about the role of imagination in hypnosis, about the use versus omission of the word hypnosis in inductions, and about the nature of individual differences and their relation to the standardized scales. In addition, the definition appears to conflate formal and exemplar-based types of definition, and it does not seem particularly well-tuned to the interests of lay persons. The authors advance some suggestions for future definitional efforts.

  1. Teaching Statistics in APA-Accredited Doctoral Programs in Clinical and Counseling Psychology: A Syllabi Review

    Science.gov (United States)

    Ord, Anna S.; Ripley, Jennifer S.; Hook, Joshua; Erspamer, Tiffany

    2016-01-01

    Although statistical methods and research design are crucial areas of competency for psychologists, few studies explore how statistics are taught across doctoral programs in psychology in the United States. The present study examined 153 American Psychological Association-accredited doctoral programs in clinical and counseling psychology and aimed…

  2. Konsep Nilai Wajar (Fair Value) dalam Standar Akuntansi Berbasis IFRS di Indonesia Apa dan Bagaimana?

    OpenAIRE

    Heri Sukendar W.

    2012-01-01

    This paper is intended to explain the use of the concept of fair value instead of book value. The accounting world in Indonesia during the last few years have made convergency implementation of new accounting standards oriented to the International Financial Reporting Standards (IFRS) issued by International Accounting Standard Boars (IASB). This new accounting standard that emphasizes the concept of fair value compared with book value concept is outdated. The use of the concept of fair value...

  3. Advancing Research and Practice: The Revised APA Division 30 Definition of Hypnosis.

    Science.gov (United States)

    Elkins, Gary R; Barabasz, Arreed F; Council, James R; Spiegel, David

    2015-04-01

    This article describes the history, rationale, and guidelines for developing a new definition of hypnosis by the Society of Psychological Hypnosis, Division 30 of the American Psychological Association. The definition was developed with the aim of being concise, being heuristic, and allowing for alternative theories of the mechanisms (to be determined in empirical scientific study). The definition of hypnosis is presented as well as definitions of the following related terms: hypnotic induction, hypnotizability, and hypnotherapy. The implications for advancing research and practice are discussed. The definitions are presented within the article.

  4. The Use of Informational Formats to Implement APA Ethical Principles in Collecting Classroom Data.

    Science.gov (United States)

    Dolly, John P.; And Others

    1978-01-01

    Providing more information about experimental studies than required under the ethical principles formulated by the American Psychological Association can result in data bias on a specific task; overall, however, the implementation of ethical principles has little effect on data collected in classroom settings. (RL)

  5. Konsep Nilai Wajar (Fair Value dalam Standar Akuntansi Berbasis IFRS di Indonesia Apa dan Bagaimana?

    Directory of Open Access Journals (Sweden)

    Heri Sukendar W.

    2012-05-01

    Full Text Available This paper is intended to explain the use of the concept of fair value instead of book value. The accounting world in Indonesia during the last few years have made convergency implementation of new accounting standards oriented to the International Financial Reporting Standards (IFRS issued by International Accounting Standard Boars (IASB. This new accounting standard that emphasizes the concept of fair value compared with book value concept is outdated. The use of the concept of fair value of the difference and it turned out to be a trigger konvergency change the paradigm of the book value of a simpler, but less information is less transparent. The implementation of accounting standards konverjensi done gradually raises serious problems, this can be seen from postponed the application of PSAK 50 & PSAK 55 in the banking industry. Knowledge and experience of inadequate is a priority of fair value implementation difficulties.

  6. Mencegah Korupsi di Pengadaan Barang dan Jasa : Apa yang sudah dan yang masih harus dilakukan?

    OpenAIRE

    Wibowo, R.A.

    2015-01-01

    This paper aims to explore and to give appreciation for the efforts which have been done by the Indonesian government to prevent corruption in public procurement, such as: (i) designing procurement organisational structure which enables more checks and balances on the system; and (ii) designing the electronic procurement system, particularly what the-called electronic purchasing which enables effective purchasing and preventing the potency of manipulation in tender processes. Nevertheless, th...

  7. Gentlemanly Orthodoxy: Critical Race Feminism, Whiteness Theory, and the APA Manual

    Science.gov (United States)

    Thompson, Audrey

    2004-01-01

    Although often viewed as burdensome, academic writing guidelines are rarely treated as actively problematic. Even progressive scholars are unlikely to challenge the cultural assumptions or political investments of academic style guides. Yet standards regarding clarity, precision, appropriateness, sensitivity, and objectivity are not politically…

  8. Quantitative Statements in Standards of Three Accrediting Bodies: APA, CACREP, and CSWE.

    Science.gov (United States)

    Peterson, Marla P.; Turner, Janet

    The accreditation manual of the Council for Accrediation of Counseling and Related Education Programs (CACREP) contains a statement that, whenever possible, criteria for assessing standards should be qualitative rather than quantitative. The study reported in this paper was conducted to gather baseline data on the extent to which accrediting…

  9. Of Course: Prerequisite Courses for Admission into APA-Accredited Clinical and Counseling Psychology Programs

    Science.gov (United States)

    Norcross, John C.; Sayette, Michael A.; Stratigis, Katerina Y.; Zimmerman, Barrett E.

    2014-01-01

    Students often inquire about which psychology courses to complete in preparation for graduate school. This study provides data that enable students and their advisors to make research-informed decisions. We surveyed the directors of the 304 American Psychological Association-accredited doctoral programs in clinical and counseling psychology (97%…

  10. Training in Strength-Based Intervention and Assessment Methodologies in APA-Accredited Psychology Programs

    Science.gov (United States)

    Nichols, Kayla; Graves, Scott L., Jr.

    2018-01-01

    The importance of identifying and building on individual strengths has been a key component of many psychoeducational theories and modalities focused on developing interventions. However, program training in this growing area is not well known. As such, this is the first study designed to ascertain the American Psychological Association-accredited…

  11. Konvergensi Standar Laporan Keuangan ke Standar Pelaporan Keuangan Internasional, Apa dan Bagaimana

    Directory of Open Access Journals (Sweden)

    Heri Sukendar W.

    2009-03-01

    Full Text Available This research aims to explain development of the convergence of financial accounting standards under IFRS outline being implemented in Indonesia. In the early part, background of the convergence from Indonesian GAAP to IFRS is discussed, both economically and politically to the latest developments in the convergence to IFRS at the present. Furthermore, it is also described the basic framework of the IFRS, which is the fundamental preparation of financial report under IFRS. At the end, this research will explain the impact of IFRS convergence on accounting and financial reporting systems, the impact of IFRS on business and the differences between IFRS and tax principles.

  12. Mencegah Korupsi di Pengadaan Barang dan Jasa : Apa yang sudah dan yang masih harus dilakukan?

    NARCIS (Netherlands)

    Wibowo, R.A.

    2015-01-01

    This paper aims to explore and to give appreciation for the efforts which have been done by the Indonesian government to prevent corruption in public procurement, such as: (i) designing procurement organisational structure which enables more checks and balances on the system; and (ii) designing the

  13. Melissa L. Anderson: APA/APAGS Award for Distinguished Graduate Student in Professional Psychology

    Science.gov (United States)

    American Psychologist, 2012

    2012-01-01

    Presents a short biography of the winner of the American Psychological Association/American Psychological Association of Graduate Students Award for Distinguished Graduate Student in Professional Psychology. The 2012 winner is Melissa L. Anderson for her ongoing commitment to understanding, treating, and preventing domestic violence in Deaf women…

  14. The Operational Equations of State. 5: The APA - Equation of State

    Science.gov (United States)

    2013-09-01

    Arlington, VA 22202-4302. Respondents should be aware that notwithstanding any other provision of law , no person shall be subject to any penalty for...physical measurements. Thermodynamic consistency means that theEOS is totally consistent with the first and second laws of thermodynamics. Remember...form equation 1. From that standpoint, the EOS reminds the classical Boyle- Mariotte-Gay- Lussac model (when the heat capacity must be function of

  15. ADA APA DENGAN KOMUNIKASI ORANG TUA-REMAJA?: PENGARUHNYA TERHADAP AGRESIVITAS REMAJA PADA SESAMA

    Directory of Open Access Journals (Sweden)

    Diana Berlianti

    2017-02-01

    Full Text Available There is a vague link between parent–adolescent communication and adolescents’ aggressiveness. Usually, the agressive perpetrators are the victims from their past experiences of abusive behavior from their surroundings. This present study aimed to examine influence among parent-adolescent communication pattern, parental physically and verbally harsh communication toward adolescents, parents-adolescents mutual avoidance, frequency of adolescents aggressivity toward others, and adolescents aggressiveness. Using Albert Bandura’s learning theoretical framework about violence messages reproduction, this study  have been conducted using 367 adolescents sample of  Bogor District and City. This report used quantitative and using cross sectional study design.  Researcher also employed  self-reported, survey methods in order to collect data. Result shown significant relation and influence among parental physically and verbally communication towards adolescents; parents-adolescents mutual avoidance; frequency of adolescents aggressivity toward others; and adolescents aggressiveness. Using Structural Equation Modelling (SEM analyses, result proved that the victims of violence usually become perpetrators in future life.

  16. Too Many References, Just Cut a Few and It Will Be Perfect: APA vs. Chicago

    Science.gov (United States)

    Matusov, Eugene

    2011-01-01

    The purpose of the author's rebuttal is to provide a sociocultural critique of Wolff-Michael Roth and Michael Cole's arguments and of the current "Mind, Culture, and Activity" ("MCA") policy regarding referencing. In sum, Roth and Cole write that some unnamed "MCA" authors (and some scholars in general) abuse the reference practice by…

  17. An overview of the major changes in the 2002 APA Ethics Code.

    Science.gov (United States)

    Knapp, Samuel; VandeCreek, Leon

    2003-06-01

    This article summarizes the major changes that were made to the 2002 Ethical Principles and Code of Conduct of the American Psychological Association. The 2002 Ethics Code retains the general format of the 1992 Ethics Code and does not radically alter the obligations of psychologists. One goal of the Ethics Committee Task Force was to reduce the potential of the Ethics Code to be used to unnecessarily punish psychologists. In addition, the revised Ethics Code expresses greater sensitivity to the needs of cultural and linguistic minorities and students. Shortcomings of the 2002 Ethics Code are discussed.

  18. Application of The APA Practice Guidelines on Suicide to Clinical Practice.

    Science.gov (United States)

    Jacobs, Douglas G; Brewer, Margaret L

    2006-06-01

    This article presents charts from The American Psychiatric Association Practice Guideline for the Assessment and Treatment of Patients with Suicidal Behaviors, part of the Practice Guidelines for the Treatment of Psychiatric Disorders Compendium, and a summary of the assessment information in a format that can be used in routine clinical practice. Four steps in the assessment process are presented: the use of a thorough psychiatric examination to obtain information about the patient's current presentation, history, diagnosis, and to recognize suicide risk factors therein; the necessity of asking very specific questions about suicidal ideation, intent, plans, and attempts; the process of making an estimation of the patient's level of suicide risk is explained; and the use of modifiable risk and protective factors as the basis for treatment planning is demonstrated. Case reports are used to clarify use of each step in this process.

  19. Kemampuan Penalaran Dan Komunikasi Matematis : Apa, Mengapa, Dan Bagaimana Ditingkatkan Pada Mahasiswa

    Directory of Open Access Journals (Sweden)

    Cita Dwi Rosita

    2014-01-01

    Full Text Available Matematika diberikan kepada semua siswa tanpa terkecuali agar terlatih berpikir secara logis, analitis, sistematis, dan kreatif. Dengan kompetensi-kompetensi tersebut diharapkan siswa dapat memiliki kemampuan menerima, mengelola, dan memanfaatkan pengetahuan yang diperolehnya untuk bertahan hidup dalam keadaan yang selalu berubah dan kompetitif. Latihan berpikir, merumuskan dan memecahkan masalah serta mengambil kesimpulan akan membantu siswa untuk mengembangkan pemikirannya atau intelegensinya. Dengan demikian, semakin banyak siswa berlatih memecahkan masalah matematis maka akan semakin mengerti dan berkembang cara berpikirnya. Kemahiran siswa dalam memecahkan masalah matematis, dipengaruhi oleh kemampuannya dalam memahami matematika. Kemampuan bernalar berperan penting dalam memahami matematika. Bernalar secara matematis merupakan suatu kebiasaan berpikir, dan layaknya suatu kebiasaan, maka penalaran semestinya menjadi bagian yang konsisten dalam setiap pengalaman-pengalaman matematis siswa. Dari pengalaman-pengalaman awal siswa belajar materi matematika, penting bagi guru untuk membantu siswa memahami bahwa penegasan-penegasan harus selalu mempunyai alasan. Komunikasi matematis berperan penting pada proses pemecahan masalah. Melalui komunikasi ide bisa menjadi objek yang dihasilkan dari sebuah refleksi, penghalusan, diskusi, dan pengembangan. Proses komunikasi juga membantu dalam proses pembangunan makna dan pempublikasian ide. Ketika para siswa ditantang untuk berpikir dan bernalar tentang matematika dan mengomunikasikan hasil pikiran mereka secara lisan atau dalam bentuk tulisan, sebenarnya mereka sedang belajar menjelaskan dan meyakinkan. Mendengarkan penjelasan lain, berarti sedang memberi kesempatan kepada siswa untuk mengembangkan pemahaman mereka.

  20. Transport Research APAS (actions de preparation, d'accompagnement et du suivi)

    DEFF Research Database (Denmark)

    Leleur, Steen; Pedersen, Karsten S.; Bendtsen, Ulla

    1996-01-01

    The aim of the study, dealing with road investments evaluation, is to deliver a single, coherent approach of the full range of road projects. The study draws together, contrasts and compares evaluation procedures and fuses them into an approach to evaluation which embraces both technical performa...

  1. The Fifth Edition of the APA "Publication Manual": Why Its Statistics Recommendations Are So Controversial.

    Science.gov (United States)

    Fidler, Fiona

    2002-01-01

    Identifies deficiencies in the new edition of the American Psychological Association's "Publication Manual," drawing on interviews with some critics and other parties. These include lack of follow-through with explanations and examples of how to report the statistics now recommended. (SLD)

  2. Manual of References, Creating Tables and Figures in Scholarly Publications: APA 6 Rules

    OpenAIRE

    Mehmet Ali Akkaya

    2016-01-01

    One precondition of contribution of a discipline to its field, to the scientific word in general and to the entire humankind is producing qualified scientific publications in the related field or discipline. National and international standard(s) provided for citing and referencing tables and figures, in addition to the content (and context) of the scientific publications might provide the relevant publication to be more widely and correctly read and reviewed. This study deals with adaptation...

  3. Guidelines for Nonsexist Language in APA Journals: Publication Manual Change Sheet 2

    Science.gov (United States)

    American Psychologist, 1977

    1977-01-01

    This second change sheet for its publication manual states the American Psychologist Association's policy on sexist language in its journals offers some general principles for journal authors to consider, and suggests some ways to avoid sexist language. (Author)

  4. Workshops Increase Students' Proficiency at Identifying General and APA-Style Writing Errors

    Science.gov (United States)

    Jorgensen, Terrence D.; Marek, Pam

    2013-01-01

    To determine the effectiveness of 20- to 30-min workshops on recognition of errors in American Psychological Association-style writing, 58 introductory psychology students attended one of the three workshops (on grammar, mechanics, or references) and completed error recognition tests (pretest, initial posttest, and three follow-up tests). As a…

  5. ECOTURISMO, GESTÃO PARTICIPATIVA E DILEMAS LOCAIS: UMA ANÁLISE NA APA DO PURAQUEQUARA

    Directory of Open Access Journals (Sweden)

    Fagno Oliveira

    2011-05-01

    Full Text Available Este artigo apresenta uma análise do contexto da gestão participativa de comunidades locais em uma área de uso sustentável prescrita no Sistema Nacional de Unidades de Conservação da Natureza (SNUC, 2000, no ato de criação, implementação e gestão dessas áreas. A pesquisa foi desenvolvida na cidade de Manaus, estado do Amazonas, em três comunidades ribeirinhas localizadas em uma Área de Proteção Ambiental em processo de implementação. A metodologia utilizada consistiu em revisão bibliográfica e utilização da técnica de observação direta intensiva. As comunidades avaliadas foram: Igarapé da Floresta, Santa Luzia e São Francisco do Mainã localizadas no rio Puraquequara. Foram entrevistadas 62 pessoas, realizando levantamento sobre “unidades de conservação, turismo, problemas locais e atuação do governo”. Os resultados obtidos apontam a necessidade de atuação do governo municipal e estadual, na execução de estratégias e planos para o conhecimento sobre áreas protegidas, conservação ambiental e participação local.

  6. What Is Psychiatry?

    Medline Plus

    Full Text Available ... Meeting Goldwater Rule Advocacy & APAPAC APA Sites APA Publishing APA Learning Center APA Foundation APA Annual Meeting ... Students International Become a Fellow APA Sites APA Publishing APA Foundation APA Learning Center APA Annual Meeting ...

  7. What Is Psychiatry?

    Medline Plus

    Full Text Available ... Annual Meeting Goldwater Rule Advocacy & APAPAC APA Sites APA Publishing APA Learning Center APA Foundation APA Annual Meeting ... Medical Students International Become a Fellow APA Sites APA Publishing APA Foundation APA Learning Center APA Annual Meeting ...

  8. As famílias Loranthaceae e Viscaceae da APA de Maricá, Rio de Janeiro, Brasil The families Loranthaceae and Viscaceae of the APA de Maricá, Rio de Janeiro, Brazil

    Directory of Open Access Journals (Sweden)

    Bianca Alsina Moreira

    1997-07-01

    Full Text Available Foram estudadas as espécies das famílias Loranthaceae e Viscaceae ocorrentes na Restinga de Maricá, RJ, cuja flora encontra-se ameaçada devido a diversas interferências que vêm alterando sua composição florística e estrutura vegetacional. Estão presentes dois gêneros, com quatro espécies para Loranthaceae e um gênero, com cinco espécies para Viscaceae. São citadas três novas ocorrências para o local e observações de campo.The species of Loranthaceae and Viscaceae which occur at "Restinga de Maricá", RJ were studied. These taxa are threatened by extinction, due to diverse interferences that are changing the floristic and vegetacional composition of the area. There are two genera with four species for Loranthaceae and one genera with five species for Viscaceae. Three new occurrences for the location are mentioned and field observations are given.

  9. THE HABITAT CHARACTERIZATION OF Cardisoma guanhumi LATREILLE, 1828 (DECAPODA, GECARCINIDAE THE APA COAST OF CORAL (PERNAMBUCO AND ALAGOAS, BRAZIL

    Directory of Open Access Journals (Sweden)

    Maria do Carmo Ferrão SANTOS

    2016-09-01

    Full Text Available In the period from July to September 2012, a survey was made of the number of burrows of blue land crab (Cardisoma guanhumi, both in twelve profiles distributed in areas of mangrove, positioned perpendicularly to the wetlands of the Una's River (Pernambuco and Camaragibe's River (Alagoas, aiming to acquire information on the distribution of holes in different types of topographies. The depth of burrows and the salinity and temperature of the water at the bottom of the burrows was registered. In Pernambuco and Alagoas, the profiles covered steep areas (with a gradient of 4.5° and shallow areas (with a gradient of 0.02°. The maximum distance between existing burrows in the profiles, ranged from 58m and 359.5m, compared to a benchmark level (RN. The burrows depths ranged from 0.45m to 1.90m, with an depth average of 0.99m (DP = 0,29. The maximum depth of the burrows can be justified by the fact that there is less availability of water in northeastern soils.It is recommended, studied the mangroves, the establishment of an exclusion zone to preserve the habitat of Cardisoma guanhumi, a distance of at least 200m above the high tide mark. Keywords: blue land crab; mangrove; burrows.

  10. El uso de recursos abiertos como apoyo en la implementación de las normas APA

    OpenAIRE

    Merelles Lourido, Mónica

    2017-01-01

    México ha puesto en marcha diferentes iniciativas desarrollando programas enfocados a desarrollar conocimiento, a través de CONACYT, INIC, SIN y la expedición de leyes para coordinar y promover el desarrollo científico y tecnológico, pasos importantes para la adopción de una cultura de la investigación (Canales, 2011). Según Ramírez (2015), las universidades se han preocupado por generar y compartir conocimiento de sus investigado...

  11. Training and education in religion/spirituality within APA-accredited clinical psychology programs: 8 years later.

    Science.gov (United States)

    Schafer, Rachel M; Handal, Paul J; Brawer, Peter A; Ubinger, Megan

    2011-06-01

    This study was a follow up investigation of Brawer et al.'s (Prof Psychol Res Pr 33(2):203-206, 2002) survey of education and training of clinical psychologists in religion/spirituality. Directors of clinical training were surveyed to determine whether changes had occurred in the coverage of religion and spirituality through course work, research, supervision, and in the systematic coverage of the content area. Results indicated an increased coverage in the areas of supervision, dedicated courses, inclusion as part of another course, and research. There was no increase in systematic coverage, but significantly more programs provided at least some coverage. The current study also assesses other areas of incorporation as well as directors' opinions regarding the importance of religion/spirituality in the field of psychology.

  12. What Is the Role and Importance of the Revised AERA, APA, NCME "Standards for Educational and Psychological Testing"?

    Science.gov (United States)

    Plake, Barbara S.; Wise, Lauress L.

    2014-01-01

    With the 2014 publication of the 5th revision of the "Standards for Educational and Psychological Testing," the cochairs of the Joint Committee for the revision process were asked to consider the role and importance of the "Standards" for the educational testing community, and in particular for members of the National Council…

  13. PARADOXOS ENTRE TAIPU DE FORA E TAIPU DE DENTRO / APA DE MARAÚ-BAHIA: TURISMO E IDENTIDADE LOCAL

    Directory of Open Access Journals (Sweden)

    Ivan Rêgo Aragão

    2011-02-01

    Full Text Available Normal 0 21 false false false PT-BR X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabela normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} O presente trabalho tem como objeto de estudo duas localidades geograficamente próximas, mas díspares em suas realidades: Taipu de Fora e de Dentro, ambas na Bahia. O objetivo foi o de realizar um estudo comparativo sobre a ocupação do espaço pelo turismo, e seus reflexos na identidade dos dois povoados. Foi realizada uma pesquisa qualitativa exploratória, primeiramente através de pesquisa bibliográfica, seguida de observação in loco e entrevistas abertas e semiestruturadas. Ainda em campo, e após a visita, buscou-se relacionar os conceitos de ‘alma do lugar’, memória, sentimento de pertença e patrimônio imaterial. A análise dos resultados foi realizada relacionando-se os relatos coletados na pesquisa exploratória, com a observação direta, buscando-se as aproximações e as diferenças na relação entre turismo, espaço e identidade. Dessa forma, a relevância deste estudo se dá ao estimular a reflexão acerca das contradições proporcionadas pela atividade turística.  

  14. Form and Style: Theses, Reports, Term Papers. Eighth Edition. Up-to-Date Information on Chicago, MLA, and APA Documentation.

    Science.gov (United States)

    Campbell, William Giles; And Others

    The eighth edition of this manual, which incorporates recent changes in bibliographical format made by "The Chicago Manual of Style" and the Modern Language Association of America, provides guidance to writers of research papers and reports in college, graduate school, business, government, and the professions. The review of the…

  15. Exploring the APA Fifth Edition "Publication Manual"'s Impact on the Analytic Preferences of Journal Editorial Board Members.

    Science.gov (United States)

    Capraro, Mary Margaret; Capraro, Robert M.

    2003-01-01

    Studied the reporting preferences of editorial board members of four scholarly journals in education and psychology with regard to analytic practices in the fifth edition of the American Psychological Association "Publication Manual." Responses of 106 board members show the movement toward reform in research reporting practices. (SLD)

  16. What Is Psychiatry?

    Medline Plus

    Full Text Available ... Rule Advocacy & APAPAC APA Sites APA Publishing APA Learning Center APA Foundation APA Annual Meeting Psychiatric ... Competency Awards & Leadership Opportunities Advocacy & APAPAC ...

  17. Análise temporal da flora nativa no entorno de unidades de conservação: APA Cachoeira das Andorinhas e FLOE Uaimii, Ouro Preto, MG

    Directory of Open Access Journals (Sweden)

    Renato Andrade Rezende

    2011-06-01

    Full Text Available A crescente fragmentação das paisagens tem contribuído para a perda da diversidade biológica nas diversas regiões brasileiras. Isso se deve, na grande maioria dos casos, à maneira desordenada com que o homem vem usando e ocupando as terras. A criação de áreas protegidas ou unidades de conservação (UC tem sido um dos principais mecanismos utilizados para a proteção da biodiversidade (in situ, além de assumir objetivos mais amplos como a proteção dos recursos hídricos, de espécies ameaçadas, dos recursos genéticos, do grau de endemismo, dos habitats, entre outros. Contudo, é preciso que haja instrumentos de avaliação periódica do seu estado de conservação, visando fornecer subsídios aos planos de manejo através da identificação das potenciais ameaças à funcionalidade ecológica dessas áreas protegidas. Com base em mapas temáticos de classificação da cobertura do solo, elaborados para os anos de 1989 e 2008, no intuito de analisar as alterações ocorridas na área de estudo neste mesmo período, este trabalho quantificou a dinâmica da flora nativa no interior e entorno da Área de Proteção Ambiental Estadual Cachoeira das Andorinhas e da Floresta Estadual do Uaimii, localizadas no Município de Ouro Preto (MG. Os resultados mostram que, ao longo dos 19 anos de comparação, a área ocupada pela flora nativa manteve-se praticamente a mesma, com índices de 82 a 83% no interior das UCs e 74% no seu entorno. Com os resultados da fragmentação, torna-se possível identificar as áreas mais críticas ou sujeitas a maior pressão antrópica e direcionar programas específicos, no âmbito gerencial, para minimizá-los.

  18. El enfoque sistémico: aplicación al subsector de agua potable y alcantarillado (A.P.A.

    Directory of Open Access Journals (Sweden)

    Jorge E. Triviño M.

    1987-09-01

    Full Text Available Al presentar en este documento una síntesis de los principios básicos del análisis de sistemas y su aplicación al sector de agua potable y saneamiento, se desea contribuir en forma práctica a la divulgación y aplicación de una ciencia relativamente joven que permite mejorar cada vez más las organizaciones y su administración, sin causar traumatismos ni ocasionar resistencias al cambio deseado, en beneficio de la salud del hombre.

  19. Guía para la Presentación de Trabajos Científicos Bajo el Estándar APA en la Universidad EAN

    OpenAIRE

    Argüelles Pabón, Denise Caroline; Calderón Rojas, Jacqueline; Ortega, Sandra Constanza; Patiño, Juan Carlos; de la Hoz, Gerardo Augusto; Cáceres, Omar Antonio; Clavijo, Sandra Bibiana; Correal, María Clara; Fresneda, Laura Cediel

    2013-01-01

    Esta es una interpretación del Manual de Publicaciones de la American Psychological Association, tercera edición en español y sexta en inglés, para el contexto de la Universidad EAN. El trabajo tiene como objetivo, establecer los lineamientos para la adecuada presentación de trabajos científicos de calidad nacional e internacional, entendidos como artículos científicos, trabajos de grado, resultados de investigación y tesis doctorales.

  20. -H.sub.2./sub.-lengthening of the internucleotide linkage in the ApA dimer can improve its conformational compatibility with its natural polynucleotide counterpart

    Czech Academy of Sciences Publication Activity Database

    Hanuš, J.; Barvík, I.; Ruszová-Chmelová, K.; Štěpánek, J.; Turpin, P. Y.; Bok, J.; Rosenberg, Ivan; Endová, Magdalena

    2001-01-01

    Roč. 29, č. 24 (2001), s. 5182-5194 ISSN 0305-1048 R&D Projects: GA AV ČR IAA4055902; GA ČR GA203/01/1166; GA MŠk VS97113 Institutional research plan: CEZ:AV0Z4055905 Keywords : phosphonate internucleotide linkage Subject RIV: CC - Organic Chemistry Impact factor: 6.373, year: 2001

  1. A Apa da Baleia Franca e o Turismo de Observação de Baleias Embarcado (Tobe: Sustentabilidade ou Exploração Animal?

    Directory of Open Access Journals (Sweden)

    Fernanda Luiza Fontoura de Medeiros

    2015-12-01

    Full Text Available O Sistema Nacional de Unidades de Conservação, regulado pela Lei 9985/2000, estabelece duas grandes categorias de Unidades de Conservação: as unidades de conservação de proteção integral e as unidades de conservação de uso sustentável. Entre as unidades de conservação de uso sustentável, as áreas de proteção ambiental caracterizam-se por serem áreas extensas, instituídas para a preservação dos processos naturais e da biodiversidade, bem como para regular as atividades humanas às características ambientais da área. Assim, no sul do estado de Santa Catarina foi instituída a Área de Proteção Ambiental da Baleia Franca (APABF, com o objetivo principal de proteger nas aguas brasileiras a baleia franca austral. Recentemente, a APABF esta sendo palco de um intenso conflito socioambiental em razão da Ação Civil Pública (ACP interposta pelo Instituto Sea Shepherd Brasil em face do Instituto Chico Mendes da Biodiversidade (ICMBIO, pedindo a condenação do ICMBIO a adotar de forma permanente, as medidas necessárias e eficazes para a proteção das baleias-francas, mediante a fiscalização das empresas que praticam a observação das baleias com uso de embarcações, com ou sem motor, a fim de impedir a violação da legislação. Este artigo consiste em um estudo de caso e visa contribuir para o conhecimento do caso do turismo de observação de baleias embarcado na APABF, através da analise da legislação aplicada, como dos atores envolvidos na controvérsia judicial e o seu reflexo para os direitos animais. A pesquisa é feita através da analise documental da legislação que caracteriza as unidades de conservação, da legislação especifica de proteção aos cetáceos, bem como dos argumentos utilizados pelas partes envolvidas na ACP.

  2. APA Summit on Medical Student Education Task Force on Informatics and Technology: Steps to Enhance the Use of Technology in Education through Faculty Development, Funding and Change Management

    Science.gov (United States)

    Hilty, Donald M.; Benjamin, Sheldon; Briscoe, Gregory; Hales, Deborah J.; Boland, Robert J.; Luo, John S.; Chan, Carlyle H.; Kennedy, Robert S.; Karlinsky, Harry; Gordon, Daniel B.; Yellowlees, Peter M.; Yager, Joel

    2006-01-01

    Objective: This article provides an overview of how trainees, faculty, and institutions use technology for acquiring knowledge, skills, and attitudes for practicing modern medicine. Method: The authors reviewed the literature on medical education, technology, and change, and identify the key themes and make recommendations for implementing…

  3. Society for Health Psychology (APA Division 38) and Society of Behavioral Medicine joint position statement on the Medicare Diabetes Prevention Program.

    Science.gov (United States)

    Fitzpatrick, Stephanie L; Wilson, Dawn K; Pagoto, Sherry L

    2017-06-01

    Beginning in January 2018, the Centers for Medicare and Medicaid Services (CMS) plans to cover the Diabetes Prevention Program (DPP), also referred to as Medicare DPP. The American Psychological Association Society for Health Psychology (SfHP) and the Society for Behavioral Medicine (SBM) reviewed the proposed plan. SfHP and SBM are in support of the CMS decision to cover DPP for Medicare beneficiaries but have a significant concern that aspects of the proposal will limit the public health impact. Concerns include the emphasis on weight outcomes to determine continued coverage and the lack of details regarding requirements for coaches. SfHP and SBM are in strong support of modifications to the proposal that would remove the minimum weight loss stipulation to determine coverage and to specify type and qualifications of "coaches."

  4. Detection of antipolymer antibodies (APA) in serum of women with silicone breast implants. Introduction and performance of the assay in the RIVM

    NARCIS (Netherlands)

    de Jong WH; Spiekstra SW; van Loveren H; LPI

    1998-01-01

    Siliconen bevattende borst implantaten (SBI) worden veelvuldig gebruikt om medische en kosmetische redenen. De laatste tijd is een discussie op gang gekomen dat het aanwezig zijn van een siliconen borstimplantaat mogelijk kan leiden tot gezondheidsklachten. Recentelijk is een laboratoriumtest

  5. APA: U free Pu pin in a heterogeneous assembly to improve Pu loading in a PWR - neutronic, thermo-hydraulic and manufacturing studies

    International Nuclear Information System (INIS)

    Porta, J.; Puill, A.; Bauer, M.; Matheron, P.

    1999-01-01

    After having presented the specific context of France with respect to the fuel cycle and reprocessing, the problem of plutonium fuel utilization is posed. If one of the solutions, a pressurized water reactor (PWR) with an increased moderation ratio seems possible, it entails making excessive changes to the reactor, the control systems, and the general architecture of the steam supply system. Another solution consists in modifying the fuel itself so as to eliminate conversion on 238 U by using plutonium (Pu) in a neutronically inert matrix. However, the disadvantage of this type of fuel is that it has very low Doppler and draining coefficients and a very small delayed neutron fraction. To enable using these fuels, a heterogeneous assembly has to be defined, in which standard UO 2 rods provide the physical properties required to ensure acceptable safety coefficients. (author)

  6. Journal article reporting standards for qualitative primary, qualitative meta-analytic, and mixed methods research in psychology: The APA Publications and Communications Board task force report

    OpenAIRE

    Levitt, H. M.; Bamberg, M.; Creswell, J. W.; Frost, D. M.; Josselson, R.; Suárez-Orozco, C.

    2018-01-01

    The American Psychological Association Publications and Communications Board Working Group on Journal Article Reporting Standards for Qualitative Research (JARS–Qual Working Group) was charged with examining the state of journal article reporting standards as they applied to qualitative research and with generating recommendations for standards that would be appropriate for a wide range of methods within the discipline of psychology. These standards describe what should be included in a resea...

  7. Trilhas, veredas para discussão da gestão do turismo nas APA´s : o caso APA-Guadalupe/PE/

    OpenAIRE

    Nunes Silva, Roberta

    2003-01-01

    Este trabalho tem como objetivo reunir informações para o estudo das trilhas interpretativas em áreas protegidas, destacando a sua importância no desenvolvimento das atividades relacionadas com o ecoturismo. A área objeto de estudo é a APAGuadalupe Litoral Sul de Pernambuco - que insere parte dos municípios de Sirinhaém, Rio Formoso, Tamandaré e Barreiros. Tem como pressupostos a necessidade de respeito aos atrativos naturais e culturais, sustentabilidade, educação do visitante...

  8. What Is Psychiatry?

    Medline Plus

    Full Text Available ... Reporting on Mental Health Conditions APA Blogs Annual Meeting Goldwater Rule Advocacy & APAPAC APA Sites APA Publishing APA Learning Center APA Foundation APA Annual Meeting Psychiatric News PsychiatryOnline Workplace Mental Health Sign In ...

  9. What Is Psychiatry?

    Medline Plus

    Full Text Available ... Join APA General Members Residents and Fellows Medical Students International Become a Fellow APA Sites APA Publishing APA Foundation APA Learning Center APA Annual Meeting Psychiatric News PsychiatryOnline Workplace ...

  10. What Is Psychiatry?

    Medline Plus

    Full Text Available ... Rule Advocacy & APAPAC APA Sites APA Publishing APA Learning Center APA Foundation APA Annual Meeting Psychiatric News ... and Fellows Medical Students International close menu Psychiatrists Education Practice Cultural Competency Awards & Leadership Opportunities Advocacy & APAPAC ...

  11. What Is Psychiatry?

    Medline Plus

    Full Text Available ... Rule Advocacy & APAPAC APA Sites APA Publishing APA Learning Center APA Foundation APA Annual Meeting Psychiatric News ... training then spends at least three additional years learning the diagnosis and treatment of mental health, including ...

  12. What Is Psychiatry?

    Medline Plus

    Full Text Available ... Advocacy & APAPAC APA Sites APA Publishing APA Learning Center APA Foundation APA Annual Meeting Psychiatric News PsychiatryOnline ... or troubling symptoms so the patient can function better. Depending on the extent of the problem, treatment ...

  13. What Is Psychiatry?

    Science.gov (United States)

    ... Families Become an APA Member Learn More Explore APA Psychiatrists Residents & Medical Students Patients & Families About APA ... Psychiatric News Message from President APA Blogs Join APA General Members Residents and Fellows Medical Students International ...

  14. What Is Psychiatry?

    Medline Plus

    Full Text Available ... Families Become an APA Member Learn More Explore APA Psychiatrists Residents & Medical Students Patients & Families About APA ... Psychiatric News Message from President APA Blogs Join APA General Members Residents and Fellows Medical Students International ...

  15. Warning Signs of Mental Illnesses

    Science.gov (United States)

    ... Families Become an APA Member Learn More Explore APA Psychiatrists Residents & Medical Students Patients & Families About APA ... Psychiatric News Message from President APA Blogs Join APA General Members Residents and Fellows Medical Students International ...

  16. What Is Psychiatry?

    Medline Plus

    Full Text Available ... Climate Change and Mental Health Connections Coping After Disaster, Trauma Internet Gaming Share Your Story Suicide Prevention ... Fellows Medical Students International Become a Fellow APA Sites APA Publishing APA Foundation APA Learning Center APA ...

  17. The American Academy of Clinical Neuropsychology, National Academy of Neuropsychology, and Society for Clinical Neuropsychology (APA Division 40) 2015 TCN Professional Practice and 'Salary Survey': Professional Practices, Beliefs, and Incomes of U.S. Neuropsychologists.

    Science.gov (United States)

    Sweet, Jerry J; Benson, Laura M; Nelson, Nathaniel W; Moberg, Paul J

    2015-01-01

    The current survey updated professional practice and income information pertaining to clinical neuropsychology. Doctoral-level members of the American Academy of Clinical Neuropsychology, Division 40 (Clinical Neuropsychology) of the American Psychological Association, and the National Academy of Neuropsychology and other neuropsychologists, as well as postdoctoral trainees in the Association of Postdoctoral Programs in Clinical Neuropsychology and at other training sites were invited to participate in a web-based survey in early 2015. The sample of 1777 respondents, of whom 1579 were doctoral-level practitioners and 198 were postdoctoral trainees, was larger than the prior 2010 income and practice survey. The substantial proportional change in gender has continued, with women now a clear majority in the postdoctoral trainee sample as well as in the practitioner sample. Dissimilar from the median age trajectory of American Psychological Association members, the median age of clinical neuropsychologists remains essentially unchanged since 1989, indicating a substantial annual influx of young neuropsychologists. The question of whether the Houston Conference training model has become an important influence in the specialty can now be considered settled in the affirmative among postdoctoral trainees and practitioners. Testing assistant usage remains commonplace, and continues to be more common in institutions. The vast majority of clinical neuropsychologists work full-time and very few are unemployed and seeking employment. The numbers of neuropsychologists planning to retire in the coming 5-10 years do not suggest a "baby boomer" effect or an unexpected bolus of planned retirements in the next 10 years that would be large enough to be worrisome. Average length of time reported for evaluations appears to be increasing across time. The most common factors affecting evaluation length were identified, with the top three being: (1) goal of evaluation, (2) stamina/health of examinee, and (3) age of examinee. Pediatric specialists remain more likely than others to work part-time, more likely to work in institutions, report lower incomes than respondents with a lifespan professional identity, and are far more likely to be women. Incomes continue to vary considerably by years of clinical practice, work setting, amount of forensic practice, state, and region of country. Neurologists are the number one referral source in institutions and in private practice, as well as for pediatric, adult, and lifespan practitioners. Learning disability is no longer among the top five conditions seen by pediatric neuropsychologists; traumatic brain injury and seizure disorder are common reasons for clinical evaluations at all age ranges. There is a continued increase in forensic practice and a clear consensus on the use of validity testing. There is a substantial interest in subspecialization board certification, with the greatest interest evident among postdoctoral trainees. Income satisfaction, job satisfaction, and work-life balance satisfaction are higher for men. Job satisfaction varies across general work setting and across age range of practice. Work-life balance satisfaction is moderately correlated with income satisfaction and job satisfaction. Again in this five-year interval survey, a substantial majority of respondents reported increased incomes, despite experiencing substantial negative practice effects related to changes in the US health care system. Numerous breakdowns related to income and professional activities are provided. Professional practice survey information continues to provide valuable perspectives regarding consistency and change in the activities, beliefs, and incomes of US clinical neuropsychologists.

  18. Turismo, direito ambiental e conflitos na produção do espaço: o caso da reserva Imbassaí e seu entorno, na APA Litoral norte da Bahia

    OpenAIRE

    MACHADO, Cláudia Novaes

    2008-01-01

    Esta pesquisa apresenta um estudo de caso referente ao Complexo Turístico-Hoteleiro Reserva Imbassaí e seu entorno - Imbassaí, Barro Branco e Sucuiu - na Área de Proteção Ambiental Litoral Norte do Estado da Bahia considerando a aplicação do Direito Ambiental na produção do espaço para o turismo. A fundamentação teórico-conceitual foi embasada nas categorias geográficas de análise forma, função, estrutura e processo - Santos (1985), turismo - Rodrigues (1997), produção do espaço - Harvey (200...

  19. Avaliação antropométrica dos alunos portadores de Síndrome de Down e da equipe de atendimento da Associação de Pais e Amigos dos Excepcionais (APAE) de Araras

    OpenAIRE

    Ribeiro, Carolina Barbosa

    2013-01-01

    A Síndrome de Down é um distúrbio genético e metabólico, que pode afetar o estado nutricional, por essa razão, são necessárias avaliações e intervenções nutricionais para que esses indivíduos possam ter uma melhora na qualidade de vida, no crescimento e desenvolvimento. O objetivo foi avaliar o estado antropométrico dos 19 alunos portadores de Síndrome de Down atendidos na Associação de Pais e Amigos dos Excepcionais de Araras, unidade Escola. Também foi avaliado o estado nutri...

  20. A eficiência da semeadura direta para a revegetação de uma jazida de cascalho na fazenda Água Limpa, APA Gama Cabeça de Veado, Brasília, DF

    OpenAIRE

    Santos, Larissa Carolina Amorim dos

    2011-01-01

    A recuperação de áreas degradadas pela mineração é um processo lento e oneroso. O plantio de mudas nativas tem sido a maneira mais comum de se revegetar áreas mineradas. Uma alternativa a esse método é a semeadura direta no substrato exposto. Redução de custo, incentivo aos processos de regeneração natural, maior diversidade de espécies e menor manutenção são algumas vantagens desse método. Este trabalho, portanto, visou à avaliação do sucesso do estabelecimento de espécies arbóreas nativas d...

  1. Revisión acerca de las normas para la presentación de referencias bibliográficas según el estilo de la American Psychological Association (APA

    Directory of Open Access Journals (Sweden)

    Cristian Carlos Abalos

    2003-01-01

    Full Text Available Numerosas instituciones han hecho accesibles sus datos a través de la infraestructura de comunicaciones que ofrece la internet, a través de la World Wide Web. Su amplia versatilidad permite trabajar con ficheros de texto, sonido, imágenes fijas y/o en movimiento, así como la capacidad de acceder desde ella a todos los otros servicios de internet. Bajo este esquema tecnológico surgieron los distintos recursos electrónicos de información. Para la preparación de un informe en los ámbitos académicos y científicos, cada día es más necesario citar y referirse a documentos e información obtenida a través de medios electrónicos. La utilización de estos recursos hace necesario contar con un sistema que determine un criterio adecuado para citarlos. En este artículo, se presenta una síntesis del estilo sugerido por la American Psychological Association para citar documentos electrónicos consultados a través de la internet.

  2. Diversidade e uso de recursos medicinais do carrasco na APA da Serra da Ibiapaba, Piauí, Nordeste do Brasil Diversity and use of medicinal resources of "carrasco" in the EPA of Serra da Ibiapaba, Piauí, Northeast Brazil

    Directory of Open Access Journals (Sweden)

    E.M.F. Chaves

    2012-01-01

    Full Text Available O presente estudo foi realizado na Área de Proteção Ambiental da Serra da Ibiapaba no município de Cocal, Piauí. Objetivou-se realizar o levantamento das plantas utilizadas pela comunidade, das partes usadas, das indicações, das formas de uso e de administração dessas plantas. Foram realizadas 80 entrevistas com 100% dos moradores de notório saber, residentes no município que utilizavam e/ou comercializavam plantas de uso medicinal. Para definição da amostra utilizou-se o método de bola de neve. Em incursões guiadas por membros da comunidade, foram coletadas as etnoespécies citadas. Após essa etapa, as espécies foram identificadas em laboratório e calculado o Fator de Consenso dos Informantes (FCI para cada categoria de doença. O material foi incorporado ao acervo do Herbário Graziela Barroso (TEPB/UFPI. Foram identificadas 76 espécies, distribuídas em 61 gêneros e 36 famílias. Sobresairam-se Leguminosae com 22 espécies (28,9%, seguida por Euphorbiaceae com 6 (7,8%, e Solanaceae 4 (5,2%. Os gêneros Croton L. e Hymenaea L. obtiveram o maior destaque, somando 8 (10,5% do total de espécies. As espécies mais presentes nas indicações de uso foram Ximenia americana com 14 (5,9%, Tabebuia impetiginosa com 9 (3,9% e Anacardium occidentale com 7 (2,9%. Observou-se que 80,5% dos entrevistados tinham mais de 50 anos e residiam no município a mais de 20 anos, sendo que 70% possuíam apenas ensino fundamental incompleto e 20 % eram analfabetos. Houve maior consenso entre os informantes para tratamento das doenças do sistema respiratório (0,66 e do aparelho digestório (0,65. A maioria das indicações de usos 81 (34,17% relatados para 28 (36,8% das espécies visavam curar males do sistema respiratório, tais como asma, bronquite, gripe, inflamação na garganta, pneumonia e sinusite. Para o preparo dos remédios, as partes mais utilizadas foram as cascas (30,5%, as folhas (29,4% e as raízes (12,6%. As preparações mais comuns foram os chás, garrafadas e lambedores, administrados por via oral. Os resultados sinalizaram para a importância do potencial bioativo da vegetação do carrasco.The present study was carried out in the Environmental Protection Area of Serra da Ibiapaba, in Cocal Municipality, Piauí. The study aimed to perform a survey of the plants used by the community, including used parts, recommended use, forms of use and administration of these plants. A total of 80 interviews were done with 100% of denizens with noteworthy knowledge who lived in that municipality and used and/or commercialized plants of medicinal use. To define the sample the snowball method was adopted. In tours guided by members of the community, the cited ethnospecies were collected. After this stage, the species were identified in the laboratory and the Informant Consensus Factor (ICF was calculated for each disease category. The material was incorporated in the collection of Herbarium Graziela Barroso (TEPB/UFPI. A total of 76 species were identified, distributed into 61 genera and 36 families. Leguminosae was the major family with 22 species (28.9%, followed by Euphorbiaceae with 6 (7.8% and Solanaceae with 4 (5.2%. Croton L. and Hymenaea L. were the most important genera, comprising 8 (10.5% of the total species. The species most commonly recommended for medicinal use were Ximenia americana with 14 (5.9%, Tabebuia impetiginosa with 9 (3.9% and Anacardium occidentale with 7 (2.9%. The age of 80.5% of the interviewees was over 50 years and they had been living in the municipality for more than 20 years, while 70% had only incomplete elementary education and 20% were illiterate. There was greater consensus among the informants for treatment of respiratory diseases (0.66 and problems of the digestive system (0.65. The most common recommendation of use, 81 (34.17%, reported for 28 (36.8% of the species, aimed to cure problems of the respiratory system, such as asthma, bronchitis, influenza, inflammation of the throat, pneumonia, and sinusitis. In the preparation of medicines, the parts most commonly used were the bark (30.5%, the leaves (29.4% and the roots (12.6%. The most common preparations were tea, balm and lickers, administered orally. The results indicated the importance of the bioactive potential of "carrasco" vegetation.

  3. El artículo científico para revista académica: Pautas para su planificación y edición de acuerdo con el modelo APA

    Directory of Open Access Journals (Sweden)

    María Elena Camacho Villalobos

    2014-07-01

    Full Text Available A partir de la experiencia de las autoras como directoras y editoras de revistas académicas, en comités editoriales, en arbitrajes de textos, en cursos impartidos para la redacción de artículos y sobre la escritura en general, y en la revisión filológica, se propone este artículo. En estas experiencias han detectado diversas dificultades en la escritura de artículos, por lo cual plantean los indicadores de calidad e información pertinente para la escogencia del medio en que se quiere publicar; formato general, modalidades y partes constituyentes del artículo; la construcción de la cohesión y la coherencia; la planificación del texto y la elaboración de las paráfrasis. Bosquejan elementos que se deben revisar antes de enviar el artículo, así como estrategias para gestionar la publicación en la revista. Con ello, atienden detalles que tienen que ver con un asunto pragmático y formal. La síntesis y el análisis constituyen herramientas para la elaboración de la paráfrasis, por tanto, su abordaje se ha considerado relevante debido a que facilitan el acopio de información de diversas fuentes y su adecuado empleo en el documento propio. Recalcan la noción de que escribir es un acto comunicativo en el cual se debe colaborar con los potenciales lectores o lectoras con un texto cohesionado, coherente, conciso y claro. Este constituye una propuesta de lingüística aplicada a la construcción del texto académico, de provecho para diversas disciplinas.

  4. El artículo científico para revista académica: Pautas para su planificación y edición de acuerdo con el modelo APA

    OpenAIRE

    Camacho Villalobos, María Elena; Rojas Porras, Marta Eugenia; Rojas Blanco, Lillyam

    2014-01-01

    A partir de la experiencia de las autoras como directoras y editoras de revistas académicas, en comités editoriales, en arbitrajes de textos, en cursos impartidos para la redacción de artículos y sobre la escritura en general, y en la revisión filológica, se propone este artículo. En estas experie ncias han detectado diversas dificultades en la escritura de artículos, por lo cual plantean los indicadores de calidad e información pertinente para la escogencia d...

  5. From the American Psychological Association to the American Psychology Association--An Organization for Psychologists or for the Discipline? 2007 Annual Report of the APA Policy and Planning Board

    Science.gov (United States)

    American Psychologist, 2008

    2008-01-01

    Each year, the American Psychological Association's Policy and Planning Board takes the pulse of the Association and the discipline as a whole and writes a report that represents the Board's best appraisal of a fundamental policy. Our main objective, however, is not simply to assess the current situation but to look forward on behalf of the…

  6. The conformational compatibility of the ApA dimer with poly(rU) improved by the -CH.sub.2./sub.- lengthening of the dimer internucleotide of the dimer internucleotide linkage - A 2D raman isothermal study

    Czech Academy of Sciences Publication Activity Database

    Hanuš, J.; Barvík, I.; Štěpánek, J.; Turpin, P. Y.; Bok, J.; Rosenberg, Ivan; Petrová, Magdalena

    2002-01-01

    Roč. 9, č. 1 (2002), s. 37-38 ISSN 1211-5894. [Meeting of the Czech and Slovak Structural Biologists /2./. 13.03.2003-15.03.2003, Nové Hrady] R&D Projects: GA ČR GA203/01/1166; GA AV ČR IAA4055902 Institutional research plan: CEZ:AV0Z4055905 Keywords : 2D Raman data Subject RIV: CE - Biochemistry

  7. Survey of vegetation and its diametric distribution in an area of cerrado sensu stricto and riparian forest fragment at Dois Irmãos stream in the Area of Environmental Protection (APA of Cafuringa, Federal District, Brazil.

    Directory of Open Access Journals (Sweden)

    José Elias de Paula

    2009-09-01

    Full Text Available All individual trees with a diameter at breast height (DBH of over 5cm, as well as the natural succession, were identified in 2,500m2 of the savannah (cerrado sensu stricto area and in 5,000m2 of the “Dois Irmãos” riparian forest vegetation (15º30’19”S and 48º06’18”W. The floristic composition of the cerrado sensu stricto was composed by 100 trees distributed in 25 species, and the riparian forest consisted of 155 trees distributed in 55 species. The natural regeneration was formed with 211 and 287 individuals in the cerrado sensu stricto and riparian forest distributed into 38 and 55 species respectively. The basal areas of the trees occupied 3.40m2.ha-1 in the cerrado sensu stricto and 5.08m2.ha-1 in the riparian forest. The diametric distribution curves for both plant communities, adjusted by the Meyers equation, demonstrated a typical tendency of reversed-J shape with strongly antropic action in the 11 to 17cm diametric classes.

  8. El artículo científico para revista académica: Pautas para su planificación y edición de acuerdo con el modelo APA

    Directory of Open Access Journals (Sweden)

    María Elena Camacho Villalobos

    2014-01-01

    Full Text Available A partir de la experiencia de las autoras como directoras y editoras de revistas académicas, en comités editoriales, en arbitrajes de textos, en cursos impartidos para la redacción de artículos y sobre la escritura en general, y en la revisión filológica, se propone este artículo. En estas experie ncias han detectado diversas dificultades en la escritura de artículos, por lo cual plantean los indicadores de calidad e información pertinente para la escogencia del medio en que se quiere publicar; formato general, modalidades y partes constituyentes de l artículo; la construcción de la cohesión y la coherencia; la planificación del texto y la elaboración de las paráfrasis. Bosquejan elementos que se deben revisar antes de enviar el artículo, así como estrategias para gestionar la publicación en la revist a. Con ello, atienden detalles que tienen que ver con un asunto pragmático y formal. La síntesis y el análisis constituyen herramientas para la elaboración de la paráfrasis, por tanto, su abordaje se ha considerado relevante debido a que facilitan el acopi o de información de diversas fuentes y su adecuado empleo en el documento propio. Recalcan la noción de que escribir es un acto comunicativo en el cual se debe colaborar con los potenciales lectores o lectoras con un texto cohesionado, coherente, conciso y claro. Este constituye una propuesta de lingüística aplicada a la construcción del texto académico, de provecho para diversas disciplinas.

  9. Fitossociologia de um fragmento de cerrado sensu stricto na APA do Paranoá, DF, Brasil Phytosociology of a cerrado sensu stricto fragment at the Paranoá Environmental Protection Area, DF, Brazil

    Directory of Open Access Journals (Sweden)

    Sérgio Lelis Assunção

    2004-12-01

    Full Text Available Este estudo foi conduzido no Distrito Federal, no Centro Olímpico da Universidade de Brasília. O local é um dos poucos remanescentes de vegetação natural no perímetro urbano de Brasília. O objetivo do trabalho foi estudar a composição florística e a fitossociologia do cerrado sensu stricto, visando obter subsídios para um plano de conservação da área. Foram alocadas aleatoriamente dez parcelas de 20×50m (1.000m². Foram incluídos na amostragem todos os troncos com diâmetro maior ou igual a 5cm, obtidos a 30cm do solo. Foram amostradas 54 espécies distribuídas em 44 gêneros e 30 famílias. A família Leguminosae apresentou o maior número de espécies (9, seguida da Malpighiaceae (4 e Vochysiaseae (4. As espécies com maior Índice do Valor de Importância foram Stryphnodendron adstringens (Mart. Coville, Styrax ferrugineus Nees & Mart., Ouratea hexasperma (A. St.-Hill., Caryocar brasiliense Cambess. e Kielmeyera coriacea (Spreng. Mart. O índice de Shannon (H'= 3,41 comprovou a alta diversidade da área. A densidade foi de 882 árvores por hectare e a área basal de 9,53m²/ha.This study was conducted in a remnant of cerrado sensu stricto at the Olimpic Center of the University of Brasília, at the Paranoá Environmental Protection Area - DF. The site is one of the few remnants of natural vegetation within the urban perimeter of Brasília. The objective was to investigate the floristic composition and the phytosociology of the cerrado sensu stricto to gather information for a conservation plan. Ten 20×50m (1,000m² plots were ramdonly located and all woody individuals with dbh equal or greater than 5cm at 30cm from ground level were identified and measured. A total of 54 species in 44 genera and 30 families were found at the site. Leguminosae had the most species (9, followed by Malpighiaceae (4 and Vochysiaseae (4. The highest importance values were for Stryphnodendron adstringens (Mart. Coville, Styrax ferrugineus Nees & Mart., Ouratea hexasperma (A. St.-Hill., Caryocar brasiliense Cambess. and Kielmeyera coriacea (Spreng. Mart. Shannon index (H'=3.41 suggests high diversity. Community density was 822 trees per ha with basal area of 9.53m².ha-1.

  10. Structure and dynamics of the ApA, ApC, CpA and CpC RNA dinucleoside monophosphates resolved with NMR scalar spin-spin couplings

    Czech Academy of Sciences Publication Activity Database

    Vokáčová, Zuzana; Schneider, Bohdan; Buděšínský, Miloš; Rosenberg, Ivan; Šponer, Jiří; Sychrovský, Vladimír

    2009-01-01

    Roč. 16, 1a (2009), b52-b52 ISSN 1211-5894. [Meeting of the Czechoslovak and Slovak Biologists /7./. 12.03.2009-14.03.2009, Nové Hrady] R&D Projects: GA AV ČR IAA400550701 Institutional research plan: CEZ:AV0Z40550506; CEZ:AV0Z50040507 Keywords : NMR * dinucleoside monophosphate Subject RIV: CF - Physical ; Theoretical Chemistry

  11. Structure and dynamics of the ApA, ApC, CpA and CpC RNA dinucleoside monophosphates resolved with NMR scalar spin-spin couplings

    Czech Academy of Sciences Publication Activity Database

    Vokáčová, Zuzana; Buděšínský, Miloš; Rosenberg, Ivan; Schneider, Bohdan; Šponer, Jiří; Sychrovský, Vladimír

    2009-01-01

    Roč. 113, č. 4 (2009), s. 1182-1191 ISSN 1520-6106 R&D Projects: GA AV ČR IAA400550701 Institutional research plan: CEZ:AV0Z40550506; CEZ:AV0Z50040507; CEZ:AV0Z50520701 Keywords : RNA * NMR * MD Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 3.471, year: 2009

  12. La protection et la valorisation juridique de la biodiversité de la Caraïbe et des Guyanes : propriété intellectuelle et dispositif APA

    OpenAIRE

    Castets-Renard, Céline

    2012-01-01

    Cet article a pour objectif de montrer les principales conditions nécessaires à l’émergence d’un marché portant sur des ressources génétiques dans la Caraïbe et les Guyanes, dans un souci de valorisation et de protection de la biodiversité, conformément au dispositif d’accès et de partage des avantages prévu par la Convention de Rio sur la biodiversité (1992). This article’s aim is to show the main conditions to encourage the emerging of a market on genetic ressources in Caraïbe and Guyane...

  13. What Is Psychiatry?

    Medline Plus

    Full Text Available ... Mental Health Conditions APA Blogs Annual Meeting Goldwater Rule Advocacy & APAPAC APA Sites APA Publishing APA Learning ... seem to lift or problems functioning, causing everyday life to feel distorted or out of control. Diagnosing ...

  14. What Is Psychiatry?

    Medline Plus

    Full Text Available ... More Topics A – Z Ask An Expert Climate Change and Mental Health Connections Coping After Disaster, Trauma ... APA General Members Residents and Fellows Medical Students International Become a Fellow APA Sites APA Publishing APA ...

  15. What Is Psychiatry?

    Medline Plus

    Full Text Available About APA APA's Vision, Mission, Values, and Goals Meet Our Organization Read APA Organization Documents and Policies Work at APA Contact Us Newsroom News Releases Message from ...

  16. What Is Psychiatry?

    Medline Plus

    Full Text Available About APA APA's Vision, Mission, Values, and Goals Meet Our Organization Read APA Organization Documents and Policies Work at APA Contact Us Newsroom News Releases Message from the President Reporting on ...

  17. What Is Psychiatry?

    Medline Plus

    Full Text Available ... Our Organization Read APA Organization Documents and Policies Work at APA Contact Us Newsroom News Releases Message from the President Reporting on Mental Health Conditions APA Blogs Annual Meeting Goldwater Rule Advocacy & APAPAC APA Sites APA Publishing APA Learning ...

  18. What Is Psychiatry?

    Medline Plus

    Full Text Available ... Rule Advocacy & APAPAC APA Sites APA Publishing APA Learning Center APA Foundation APA Annual Meeting Psychiatric News PsychiatryOnline Workplace Mental Health Sign In Join General Residents and Fellows Medical Students International close menu Psychiatrists Education Practice Cultural Competency ...

  19. What Is Psychiatry?

    Medline Plus

    Full Text Available About APA APA's Vision, Mission, Values, and Goals Meet Our Organization Read APA Organization Documents and Policies Work at APA Contact Us Newsroom News Releases Message from the President Reporting on Mental Health Conditions APA Blogs Annual Meeting Goldwater ...

  20. 75 FR 5888 - Federal Manufactured Home Construction and Safety Standards and Other Orders: HUD Statements That...

    Science.gov (United States)

    2010-02-05

    ....C. 551 et seq.) (the APA) definition of a ``rule.'' The APA definition states, in pertinent part... the APA, courts have developed extensive case law interpreting the APA's definition of a rule. (See, e... demonstrating Congress's intent to incorporate the APA's definition of a rule as developed by the courts, except...

  1. What Is Psychiatry?

    Medline Plus

    Full Text Available ... to help solve other problems in specific ways. Cognitive behavior therapy is a goal-oriented therapy focusing ... Member Learn More Explore APA Psychiatrists Residents & Medical Students Patients & Families About APA Work At APA Annual ...

  2. What Is Psychiatry?

    Medline Plus

    Full Text Available About APA APA's Vision, Mission, Values, and Goals Meet Our Organization Read APA Organization Documents and Policies ... on long-term medication treatment will need to meet with their psychiatrist periodically to monitor the effectiveness ...

  3. What Is Psychiatry?

    Medline Plus

    Full Text Available ... Values, and Goals Meet Our Organization Read APA Organization Documents and Policies Work at APA Contact Us Newsroom News Releases Message from the President Reporting on Mental Health Conditions APA Blogs Annual Meeting Goldwater Rule Advocacy & ...

  4. What Is Psychiatry?

    Medline Plus

    Full Text Available ... APA's Vision, Mission, Values, and Goals Meet Our Organization Read APA Organization Documents and Policies Work at APA Contact Us ... everyday life to feel distorted or out of control. Diagnosing Patients Because they are physicians, psychiatrists can ...

  5. What Is Psychiatry?

    Medline Plus

    Full Text Available ... Our Organization Read APA Organization Documents and Policies Work at APA Contact Us Newsroom News Releases Message from the President Reporting on Mental Health Conditions APA Blogs Annual Meeting Goldwater Rule Advocacy & ...

  6. 77 FR 123 - Final Reissuance of General NPDES Permits (GP) for Facilities Related to Oil and Gas Extraction

    Science.gov (United States)

    2012-01-03

    ... Administrative Procedure Act (APA), or any other law, to publish general notice of proposed rulemaking.'' The RFA... NPDES general permits are permits, not rulemakings, under the APA and thus not subject to APA rulemaking...

  7. What Is Psychiatry?

    Medline Plus

    Full Text Available ... APA's Vision, Mission, Values, and Goals Meet Our Organization Read APA Organization Documents and Policies Work at APA Contact Us ... is the branch of medicine focused on the diagnosis, treatment and prevention of mental, emotional and behavioral ...

  8. 76 FR 45792 - Proposed Reissuance of a General NPDES Permit for Facilities Related to Oil and Gas Extraction

    Science.gov (United States)

    2011-08-01

    ... proposed rule'' for which the agency ``is required by section 553 of the Administrative Procedure Act (APA... permits, not rulemakings, under the APA and thus not subject to APA rulemaking requirements or the RFA...

  9. The Army Preposition Afloat Program: Is It a Program We Need?

    National Research Council Canada - National Science Library

    Curl, William

    1998-01-01

    ... of most required classes. This paper addresses the evolution of the APA program, describes the current and planned APA program, discusses management of the APA, and looks critically at the value of the program in support...

  10. What Is Psychiatry?

    Medline Plus

    Full Text Available ... has an advanced degree, most commonly in clinical psychology, and often has extensive training in research or ... Member Learn More Explore APA Psychiatrists Residents & Medical Students Patients & Families About APA Work At APA Annual ...

  11. 24 CFR 3280.304 - Materials.

    Science.gov (United States)

    2010-04-01

    ... APA Trademarks)—PS 1-95. APA Design/Construction Guide, Residential and Commercial—APA E30-P-1996...-Plywood Beams—APA H-815E (PDS Supplement #5), 1995. Panel Design Specification—APA D410A, 2004. Design and Fabrication of Glued Plywood-Lumber Beams—APA-S 812Q, Suppl. 2-1992. Design and Fabrication of Plywood Curved...

  12. What Is Psychiatry?

    Medline Plus

    Full Text Available ... Values, and Goals Meet Our Organization Read APA Organization Documents and Policies Work at APA Contact Us ... Competency Awards & Leadership Opportunities Advocacy & APAPAC ...

  13. 77 FR 21099 - Public Water System Supervision Program Approval for the State of Ohio

    Science.gov (United States)

    2012-04-09

    ... the National Primary Drinking Water Regulations, including the Administrative Penalty Authority (APA... the APA since October 1, 1999, with amendments effective on October 17, 2003. Ohio EPA's revised...

  14. Determination of cephalosporin acylase activity by biological and ...

    African Journals Online (AJOL)

    PRECIOUS

    2009-12-01

    Dec 1, 2009 ... microorganisms with cephalosporin acylase activity was developed. The core part of cephalosporin was replaced by 6-amino penicillinic acid (6-APA) to generate new substrates glutaryl-6-APA and adipoyl-6-APA for screen- ing. Serratia marcescens that is sensitive to 6-APA and resistant to penicillin G, ...

  15. 75 FR 37730 - National Emission Standards for Hazardous Air Pollutants From Petroleum Refineries

    Science.gov (United States)

    2010-06-30

    ... reference. Section 553 of the Administrative Procedure Act (APA), 5 U.S.C. 553(b)(B), provides that, when an... 553(b)(B) of the APA, the procedures in section 307(d) in subsection 553(b) of the APA, the procedures... subject to notice and comment requirements under the APA or any other statute (see Section I of this...

  16. 75 FR 39633 - Extension of Deadline for Action on Section 126 Petition From New Jersey

    Science.gov (United States)

    2010-07-12

    ... Procedures Act (APA) C. Effective Date Under the APA III. Statutory and Executive Order Reviews A. Executive... Procedures Act (APA) This document is a final agency action, but may not be subject to the notice-and-comment requirements of the APA, 5 U.S.C. 553(b). The EPA believes that, because of the limited time provided to make a...

  17. 42 CFR 137.309 - How are NEPA and NHPA obligations typically enforced?

    Science.gov (United States)

    2010-10-01

    ... may only be filed in Federal court under the provisions of the APA, 5 U.S.C. 701-706. Under the APA, a... the court's views for those of the agency. Jury trials and civil discovery are not permitted in APA... injunctive relief to the interested party. No money damages or fines are permitted in APA proceedings. ...

  18. 77 FR 55695 - Approval and Promulgation of Implementation Plans; Virginia; Revisions to the State...

    Science.gov (United States)

    2012-09-11

    ... Administrative Procedure Act (APA). This exemption in the APA authorizes agencies to dispense with public... otherwise provided for in the APA. DATES: This action is effective September 11, 2012. ADDRESSES: EPA has...'' exemption in section 553(b)(3)(B) of the Administrative Procedure Act (APA). This exemption authorizes...

  19. 26 CFR 1.6038A-3 - Record maintenance.

    Science.gov (United States)

    2010-04-01

    ... maintenance requirement to particular documents. (4) Agreement as part of APA process. An agreement with a... Agreement (APA) process at any time during the APA process, insofar as the agreement relates to the subject matter of the APA. (f) U.S. maintenance—(1) General rule. Records that must be maintained under this...

  20. 75 FR 69889 - Extension of Deadline for Action on the Second Section 126 Petition From New Jersey

    Science.gov (United States)

    2010-11-16

    ... Act (APA) C. Effective Date Under the APA III. Statutory and Executive Order Reviews A. Executive... Administrative Procedures Act (APA) This document is a final agency action, but may not be subject to the notice-and-comment requirements of the APA, 5 U.S.C. 553(b). The EPA believes that, because of the limited...

  1. 78 FR 60226 - Amendments To Implement Certain Provisions of the Moving Ahead for Progress in the 21st Century...

    Science.gov (United States)

    2013-10-01

    ... available to Federal agencies under the Administrative Procedure Act (APA). DATES: Effective Date: This... public comment under procedures required by the APA, as provided in 5 U.S.C. 553(b) and (c). The APA, in... receiving public comment, in accordance with the APA. For these same reasons, the rule will be effective on...

  2. Engineering Psychology Handbook AY 2012 - 2013

    Science.gov (United States)

    2012-08-01

    APA -style title page (as described in the APA Publication Manual , 6th Edition )  Abstract...Documentation of Academic Work (2011), The Little, Brown Handbook and especially the sixth edition of the APA Publication Manual should answer most of your...References section of your paper. The sixth edition of the APA Publication Manual provides guidance on citing various types of references. Refer

  3. Deciphering the Mechanism of Alternative Cleavage and Polyadenylation in Mantle Cell Lymphoma (MCL)

    Science.gov (United States)

    2015-12-01

    event. The discovery that transformed and rapidly proliferating cells use alternative cleavage and polyadenylation ( APA ) to shorten the 3´UTR of their... APA . However, the mechanism that APA is still unknown. The goal of this project is to identify the mechanism of cyclin D1 APA regulation in cancer...for APA in MCL. In addition, by using RNA Seq. CFIm25 has been identified as an important global regulator of shortening of cyclin D1 mRNA and other

  4. The Incidence and Anatomy of Accessory Pudendal Arteries as Depicted on Multidetector-Row CT Angiography: Clinical Implications of Preoperative Evaluation for Laparoscopic and Robot-Assisted Radical Prostatectomy

    International Nuclear Information System (INIS)

    Park, Beom Jin; Sung, Deuk Jae; Kim, Min Ju; Cho, Sung Bum; Kim, Yun Hwan; Chung, Kyoo Byung; Kang, Seok Ho; Cheon, Jun

    2009-01-01

    To help preserve accessory pudendal arteries (APAs) and to ensure optimal postoperative sexual function after a laparoscopic or robot-assisted radical prostatectomy, we have evaluated the incidence of APAs as detected on multidetector-row CT (MDCT) angiography and have provided a detailed anatomical description. The distribution of APAs was evaluated in 121 consecutive male patients between February 2006 and July 2007 who underwent 64- channel MDCT angiography of the lower extremities. We defined an APA as any artery located within the periprostatic region running parallel to the dorsal vascular complex. We also subclassified APAs into lateral and apical APAs. Two radiologists retrospectively evaluated the origin, course and number of APAs; the final APA subclassification based on MDCT angiography source data was determined by consensus. We identified 44 APAs in 36 of 121 patients (30%). Two distinct varieties of APAs were identified. Thirty-three APAs (75%) coursed near the anterolateral region of the prostatic apex, termed apical APAs. The remaining 11 APAs (25%) coursed along the lateral aspect of the prostate, termed lateral APAs. All APAs originated from the internal obturator artery and iliac artery or a branch of the iliac artery such as the inferior vesical artery. The majority of apical APAs arose from the internal obturator artery (84%). Seven patients (19%) had multiple APAs. APAs are more frequently detected by the use of MDCT angiography than as suggested by previous surgical studies. The identification of APAs on MDCT angiography may provide useful information for the surgical preservation of APAs during a laparoscopic or robot-assisted radical prostatectomy

  5. Longitudinal behavior of autoimmune GH deficiency: from childhood to transition age.

    Science.gov (United States)

    De Bellis, Annamaria; Bellastella, Giuseppe; Maiorino, Maria Ida; Aitella, Ernesto; Lucci, Emma; Cozzolino, Domenico; Bellastella, Antonio; Bizzarro, Antonio; Giugliano, Dario; Esposito, Katherine

    2016-03-01

    Some cases of apparently idiopathic GH deficiency (GHD) may be caused by pituitary autoimmunity. To study the variations in pituitary function and antipituitary antibodies (APA) from childhood to transition age in patients with apparently idiopathic GHD. We conducted a longitudinal study. Pituitary function and APA detection by immunofluorescence were investigated in 24 childhood patients with isolated GHD before starting recombinant GH therapy and after the stopping of this therapy in transition age. Sera of patients positive for APA were processed by double immunofluorescence to identify their pituitary target. At diagnosis, 16 out of 24 patients were APA positive targeting only somatotrophs (group 1), while the remaining eight were APA negative (group 2). When retested off therapy, 12 out of 16 patients in group 1 persisted being APA positive, while the remaining four became negative with recovery of pituitary function. All patients in group 2 persisted being APA negative but still showing GHD. Of the 12 patients persistently APA positive, eight with confirmed GHD showed APA still targeting somatotrophs, whereas four showed APA targeting only gonadotrophs associated with isolated hypogonadotropic hypogonadism (HH). Patients with APA at middle but not at high titer in childhood may show a remission of autoimmune GHD in childhood after GH replacement therapy. As APA may shift their target in transition period, an early characterization of APA by double immunofluorescence is advisable in APA positive GHD patients showing delayed puberty, to allow an early diagnosis and an appropriate therapy, thus preventing the progression toward HH. © 2016 European Society of Endocrinology.

  6. Gonadotropin-Releasing Hormone Stimulate Aldosterone Production in a Subset of Aldosterone-Producing Adenoma

    Science.gov (United States)

    Kishimoto, Rui; Oki, Kenji; Yoneda, Masayasu; Gomez-Sanchez, Celso E.; Ohno, Haruya; Kobuke, Kazuhiro; Itcho, Kiyotaka; Kohno, Nobuoki

    2016-01-01

    Abstract We aimed to detect novel genes associated with G protein-coupled receptors (GPCRs) in aldosterone-producing adenoma (APA) and elucidate the mechanisms underlying aldosterone production. Microarray analysis targeting GPCR-associated genes was conducted using APA without known mutations (APA-WT) samples (n = 3) and APA with the KCNJ5 mutation (APA-KCNJ5; n = 3). Since gonadotropin-releasing hormone receptor (GNRHR) was the highest expression in APA-WT by microarray analysis, we investigated the effect of gonadotropin-releasing hormone (GnRH) stimulation on aldosterone production. The quantitative polymerase chain reaction assay results revealed higher GNRHR expression levels in APA-WT samples those in APA-KCNJ5 samples (P APA-WT samples, and there was a significant and positive correlation between GNRHR and LHCGR expression in all APA samples (r = 0.476, P APA-WT (n = 9), which showed higher GNRHR and LHCGR levels, had significantly higher GnRH-stimulated aldosterone response than those with APA-KCNJ5 (n = 13) (P APA-WT, and the molecular analysis including the receptor expression associated with clinical findings of GnRH stimulation. PMID:27196470

  7. What Is Psychiatry?

    Medline Plus

    Full Text Available ... APA Organization Documents and Policies Work at APA Contact Us Newsroom News ... new information specifically addressed to individuals in the European Economic Area. As described in the Privacy Policy, this website ...

  8. 29 CFR 1955.12 - Administrative law judge; powers and duties.

    Science.gov (United States)

    2010-07-01

    ... U.S.C. 554-557 (hereinafter called the APA). (b) On any procedural question not otherwise regulated by this part, the Act, or the APA, the administrative law judge shall be guided to the extent...

  9. What Is Psychiatry?

    Medline Plus

    Full Text Available ... APA's Diagnostic and Statistical Manual of Mental Disorders ( DSM-5 ), which contains descriptions, symptoms and other criteria ... is ECT? What is Telepsychiatry? Your Guide to DSM-5 Patient/Families Become an APA Member Learn ...

  10. What Is Psychiatry?

    Medline Plus

    Full Text Available ... has an advanced degree, most commonly in clinical psychology, and often has extensive training in research or ... News Message from President APA Blogs Join APA General Members Residents and Fellows Medical Students International Become ...

  11. Alkaline phosphatase activity at the southwest coast of India: A comparison of locations differently affected by upwelling..

    Digital Repository Service at National Institute of Oceanography (India)

    Mamatha, S.S.; Malik, A.; Varik, S.; Parvathi, V.; Jineesh, V.K.; Gauns, M.; LokaBharathi, P.A.

    coastal waters. As alkaline phosphatase activity (APA) indicates the status of P for primary production in aquatic environments, we asked the following question: is the level of APA indicative of P sufficiency or deficiency in coastal waters, especially...

  12. 78 FR 54248 - Notice of Public Meeting of the Interagency Steering Committee on Radiation Standards

    Science.gov (United States)

    2013-09-03

    ... reference in the development of proposals under the Administrative Procedure Act (APA) for changes to... APA process for notice and comment. Presentations of previous ISCORS public meetings are available at...

  13. Asian and Pacific American Exceptional Children. A Conversation.

    Science.gov (United States)

    Decano, Pio

    1979-01-01

    Presented in the format of an imaginary dialogue between seven educators of Asian and Pacific American (APA) backgrounds, the article addresses some issues and concerns in the training of special education personnel to work with APA handicapped children. (DLS)

  14. What Is Psychiatry?

    Medline Plus

    Full Text Available ... APA's Diagnostic and Statistical Manual of Mental Disorders ( DSM-5 ), which contains descriptions, symptoms and other criteria for ... is ECT? What is Telepsychiatry? Your Guide to DSM-5 Patient/Families Become an APA Member Learn More ...

  15. Quality Control Review of the Commonwealth of Virginia Auditor of Public Accounts The College of William & Mary Fiscal Year Ended June 30,1996

    National Research Council Canada - National Science Library

    Smolenyak, Barbara

    1998-01-01

    .... The results of most recent peer review APA, dated April 15, 1997, performed by the National State Auditors Association found that APA met the objectives of the quality control review standards...

  16. What Is Psychiatry?

    Medline Plus

    Full Text Available ... APA Foundation APA Annual Meeting Psychiatric News PsychiatryOnline Workplace Mental Health Sign In Join General Residents and Fellows Medical Students International close menu Psychiatrists Education Practice Cultural Competency Awards & Leadership Opportunities Advocacy & APAPAC ...

  17. The ethics of interrogation and the American Psychological Association: A critique of policy and process

    OpenAIRE

    Olson, Brad; Soldz, Stephen; Davis, Martha

    2008-01-01

    Abstract The Psychological Ethics and National Security (PENS) task force was assembled by the American Psychological Association (APA) to guide policy on the role of psychologists in interrogations at foreign detention centers for the purpose of U.S. national security. The task force met briefly in 2005, and its report was quickly accepted by the APA Board of Directors and deemed consistent with the APA Ethics Code by the APA Ethics Committee. This rapid acceptance was unusual for a number o...

  18. 76 FR 9658 - Approval and Promulgation of Implementation Plans; Kansas: Prevention of Significant...

    Science.gov (United States)

    2011-02-22

    ... regulations should also be effective to vacate the SIP provision itself since the SIP would be referencing a... Act (APA) good cause exemption applies here. Section 553 of the APA, 5 U.S.C. 553(b)(B), provides that... hereby finds for good cause, pursuant to section 553 of the APA, that it would be unnecessary and...

  19. 78 FR 53643 - Wage Methodology for the Temporary Non-Agricultural Employment H-2B Program; Delay of Effective Date

    Science.gov (United States)

    2013-08-30

    ... Procedure Act (APA) in proposing and adopting as a final rule the indefinite delay of the 2011 Wage rule. Our future actions likewise will be guided by the APA and other statutory requirements. The 2011 Wage... APA does not allow an agency to place a regulation ``on a shelf forever'' and that the Department has...

  20. 77 FR 30241 - Representation Procedures and Rulemaking Authority

    Science.gov (United States)

    2012-05-22

    ... the informal rulemaking procedures in the Administrative Procedure Act (APA), 5 U.S.C. 553, and... stricter requirements in sections 556 and 557 of the APA, this hearing will comply with those informal rulemaking procedures under the APA. See, e.g. United States v. Allegheny-Ludlum Steel Corp., 406 US 742...

  1. Ensuring the Availability and Quality of School Psychology Doctoral Internships

    Science.gov (United States)

    Harris, Abigail M.

    2015-01-01

    Currently, only a small percentage of internships accredited by the American Psychological Association (APA) are filled by school psychology interns and only a few of the available APA internship positions are in schools. Program data submitted online to APA indicate that many interns are in sites that meet the guidelines adopted by the Council of…

  2. 77 FR 27626 - Approval and Promulgation of Implementation Plans; Commonwealth of Kentucky; Regional Haze State...

    Science.gov (United States)

    2012-05-11

    ... section 553(b)(3)(B) of the Administrative Procedure Act (APA) which, upon finding ``good cause... related to the regional haze SIP revisions. EPA also finds that there is good cause under APA section 553...(d)(3) of the APA allows an effective date less than 30 days after publication ``as otherwise...

  3. 78 FR 16783 - Approval and Promulgation of Implementation Plans; Georgia; Control Techniques Guidelines and...

    Science.gov (United States)

    2013-03-19

    ... Administrative Procedure Act (APA) which, upon finding ``good cause,'' authorizes agencies to dispense with... action addressing approval of the Georgia RACT rules. EPA also finds that there is good cause under APA.... Section 553(d)(3) of the APA allows an effective date less than 30 days after publication ``as otherwise...

  4. 77 FR 70687 - Approval and Promulgation of Implementation Plans; Florida; Section 128 and 110(a)(2)(E)(ii) and...

    Science.gov (United States)

    2012-11-27

    ... Administrative Procedure Act (APA) which, upon finding ``good cause,'' authorizes agencies to dispense with... NAAQS into the Florida SIP. EPA also finds that there is good cause under APA section 553(d)(3) for this correction to become effective on the date of publication of this action. Section 553(d)(3) of the APA allows...

  5. 78 FR 67307 - Approval and Promulgation of Implementation Plans; Tennessee; Infrastructure Requirements for the...

    Science.gov (United States)

    2013-11-12

    ...'' exemption in section 553(b)(3)(B) of the Administrative Procedure Act (APA) which, upon finding ``good cause.... EPA also finds that there is good cause under APA section 553(d)(3) for this correction to become effective on the date of publication of this action. Section 553(d)(3) of the APA allows an effective date...

  6. 78 FR 26690 - Hours of Service (HOS) of Drivers; Application for Renewal and Expansion of American Pyrotechnics...

    Science.gov (United States)

    2013-05-07

    ... Association (APA) Exemption From the 14-Hour Rule During Independence Day Celebrations AGENCY: Federal Motor... exemption; request for comments. SUMMARY: The American Pyrotechnics Association (APA) has requested a renewal of its exemption for 48 APA member-companies from FMCSA's regulation that drivers of commercial...

  7. Wood Products Consumption for Industrial Markets in the United States, Testing a New Research Method

    Science.gov (United States)

    Craig Adair; David B. McKeever

    2013-01-01

    In early 2012, APA-The Engineered Wood Association conducted studies of three industries: institutional furniture, motor homes, and travel trailers and campers. The survey procedure was the same as that used by APA for many years. Lists of individual manufacturers were purchased, a telephone interviewing company was hired to administer a questionnaire, and APA...

  8. 2010 Annual Report of the American Psychological Association

    Science.gov (United States)

    American Psychologist, 2011

    2011-01-01

    This report presents the 2010 annual report of the American Psychological Association (APA). It provides the highlights of the association's and individual directorate's activities to APA members. APA continued its efforts to advance psychological practice and ensure the public's access to high-quality psychological services, apply psychological…

  9. American Psychological Association: Annual Report, 2008

    Science.gov (United States)

    American Psychologist, 2009

    2009-01-01

    This article presents the 2008 annual reports from the various directorates and offices of the American Psychological Association (APA). In 2008, APA continued to work on initiatives, programs, and products that lend value to the member's psychology career, support the future of their discipline, and serve the public. APA's goal is to strengthen…

  10. What Is Psychiatry?

    Medline Plus

    Full Text Available ... APA Foundation APA Annual Meeting Psychiatric News PsychiatryOnline Workplace Mental Health Sign In Join General Residents and ... Learning Center APA Annual Meeting Psychiatric News PsychiatryOnline Workplace Mental Health Terms of Use Copyright Contact © 2018 ...

  11. What Is Psychiatry?

    Medline Plus

    Full Text Available ... APA's Vision, Mission, Values, and Goals Meet Our Organization Read APA Organization Documents and Policies Work at APA Contact Us ... close menu Psychiatrists Education Practice Cultural Competency Awards & Leadership Opportunities Advocacy & APAPAC Meetings Search Directories/Databases International ...

  12. 75 FR 49820 - Delegation of Authority to the Director of Its Division of Enforcement

    Science.gov (United States)

    2010-08-16

    ... the Administrative Procedure Act (``APA'') (5 U.S.C. 553(b)(3)(A)), that this amendment relates solely..., the provisions of the APA regarding notice of the proposed rulemaking, opportunities for public..., which apply only when notice and comment are required by the APA or other law, 5 U.S.C. 603, are not...

  13. 76 FR 39769 - Delegation of Authority to the Director of Its Division of Enforcement

    Science.gov (United States)

    2011-07-07

    ... finds, in accordance with the Administrative Procedure Act (``APA'') (5 U.S.C. 553(b)(3)(A)), that this... rule. Accordingly, the provisions of the APA regarding notice of the proposed rulemaking, opportunities... Flexibility Act, which apply only when notice and comment are required by the APA or other law, 5 U.S.C. 603...

  14. 76 FR 59769 - Clarification on the Division 1.1 Fireworks Approvals Policy

    Science.gov (United States)

    2011-09-27

    ... issuing the EX approval. While APA Standard 87-1 references two instances where Division 1.1 fireworks may... test laboratory if the firework device is manufactured in accordance with APA Standard 87-1 (IBR, see... certify that the firework device conforms to the APA Standard 87-1 and that the descriptions and technical...

  15. Molecular characteristics of the KCNJ5 mutated aldosterone-producing adenomas.

    Science.gov (United States)

    Murakami, Masanori; Yoshimoto, Takanobu; Nakabayashi, Kazuhiko; Nakano, Yujiro; Fukaishi, Takahiro; Tsuchiya, Kyoichiro; Minami, Isao; Bouchi, Ryotaro; Okamura, Kohji; Fujii, Yasuhisa; Hashimoto, Koshi; Hata, Ken-Ichiro; Kihara, Kazunori; Ogawa, Yoshihiro

    2017-10-01

    The pathophysiology of aldosterone-producing adenomas (APAs) has been investigated via genetic approaches and the pathogenic significance of a series of somatic mutations, including KCNJ5 , has been uncovered. However, how the mutational status of an APA is associated with its molecular characteristics, including its transcriptome and methylome, has not been fully understood. This study was undertaken to explore the molecular characteristics of APAs, specifically focusing on APAs with KCNJ5 mutations as opposed to those without KCNJ5 mutations, by comparing their transcriptome and methylome status. Cortisol-producing adenomas (CPAs) were used as reference. We conducted transcriptome and methylome analyses of 29 APAs with KCNJ5 mutations, 8 APAs without KCNJ5 mutations and 5 CPAs. Genome-wide gene expression and CpG methylation profiles were obtained from RNA and DNA samples extracted from these 42 adrenal tumors. Cluster analysis of the transcriptome and methylome revealed molecular heterogeneity in APAs depending on their mutational status. DNA hypomethylation and gene expression changes in Wnt signaling and inflammatory response pathways were characteristic of APAs with KCNJ5 mutations. Comparisons between transcriptome data from our APAs and that from normal adrenal cortex obtained from the Gene Expression Omnibus suggested similarities between APAs with KCNJ5 mutations and zona glomerulosa. The present study, which is based on transcriptome and methylome analyses, indicates the molecular heterogeneity of APAs depends on their mutational status. Here, we report the unique characteristics of APAs with KCNJ5 mutations. © 2017 Society for Endocrinology.

  16. 78 FR 17661 - Proposed Reissuance of a General NPDES Permit for Oil and Gas Exploration Facilities in the...

    Science.gov (United States)

    2013-03-22

    ...., whichever is earlier. Hearing statements may be provided orally or in written format. Commenters providing... Administrative Procedure Act (APA), or any other law, to publish general notice of proposed rulemaking.'' The RFA... NPDES general permits are permits, not rulemakings, under the APA and thus not subject to APA rulemaking...

  17. 78 FR 70042 - Proposed Issuance of the NPDES General Permit for Oil and Gas Geotechnical Surveying and Related...

    Science.gov (United States)

    2013-11-22

    ... be provided orally or in written format. Commenters providing verbal comments are encouraged to... Act (APA), or any other law, to publish general notice of proposed rulemaking.'' The RFA exempts from... permits are permits, not rulemakings, under the APA and thus not subject to APA rulemaking requirements or...

  18. 77 FR 4813 - Proposed Reissuance of the NPDES General Permits for Oil and Gas Exploration Facilities on the...

    Science.gov (United States)

    2012-01-31

    ...) Hearing statements may be provided orally or in written format. Commenters providing oral testimony are... agency ``is required by section 553 of the Administrative Procedure Act (APA), or any other law, to..., under the APA and thus not subject to APA rulemaking requirements or the FRA. Notwithstanding that...

  19. 78 FR 39613 - Federal Pell Grant Program

    Science.gov (United States)

    2013-07-02

    .... Individuals with disabilities can obtain this document in an accessible format (e.g., braille, large print... accordance with the Administrative Procedure Act (APA) (5 U.S.C. 553). However, the APA provides that an... APA because the statutory change to prohibit a student from receiving two Federal Pell Grants in a...

  20. 75 FR 57907 - Teacher Incentive Fund

    Science.gov (United States)

    2010-09-23

    ... format (e.g., braille, large print, audiotape, or computer diskette) on request to the contact person... Rulemaking and Delayed Effective Date Under the Administrative Procedure Act (APA) (5 U.S.C. 553), the... notice-and-comment rulemaking requirements under the APA. Section 553(b) of the APA provides that an...

  1. 75 FR 9777 - Magnet Schools Assistance Program

    Science.gov (United States)

    2010-03-04

    ... accessible format (e.g., braille, large print, audiotape, or computer diskette) on request to the contact... Date Under the Administrative Procedure Act (APA) (5 U.S.C. 553), the Department is generally required... rulemaking requirements under the APA. Section 553(b) of the APA provides that an agency is not required to...

  2. What Is Psychiatry?

    Medline Plus

    Full Text Available ... APA's Vision, Mission, Values, and Goals Meet Our Organization Read APA Organization Documents and Policies Work at APA Contact Us ... Addiction and Substance Use Disorders Alzheimer's Anxiety Disorders Attention-Deficit/Hyperactivity Disorder (ADHD) Autism Spectrum Disorder Bipolar ...

  3. The Value of Peer Feedback Opportunities for Students in Writing Intensive Classes

    Science.gov (United States)

    Kennette, Lynne N.; Frank, Nichole M.

    2013-01-01

    The present study was conducted to examine the usefulness of peer feedback on APA-style research papers in a writing-intensive class. Subsequent to APA training, students were asked to review and provide feedback on a classmate's APA-style research report for both content and formatting. Performance on this research report was then compared to…

  4. What Is Psychiatry?

    Medline Plus

    Full Text Available ... Meet Our Organization Read APA Organization Documents and Policies Work at APA Contact Us Newsroom News Releases Message ... Psychiatrists Residents & Medical Students Patients & Families About APA Work At ... Use and Privacy Policy Copyright Contact © 2018 American Psychiatric Association. All Rights ...

  5. The Community College Presidency: An Asian Pacific American Perspective.

    Science.gov (United States)

    Fujimoto, M. Jack

    1996-01-01

    Analyzes the status of Asian Pacific Americans (APAs) in higher education compared to their representation in chief executive positions, describing a glass ceiling effect and common stereotypes regarding APAs. Reviews characteristics of chief executive officers in California community colleges. Provides strategies for increasing APA representation…

  6. Recurrent Pregnancy Loss

    Directory of Open Access Journals (Sweden)

    Véronique Piroux

    1997-01-01

    Full Text Available Antiphospholipid antibodies (APA are associated with thrombosis, thrombocytopenia and fetal loss but they occur in a variety of diseases. Despite many efforts, a correlation between the specificity of particular subgroups of APA and particular clinical situations remains to be established. The antigens at the origin of APA remain to be identified. We discuss here the possible links between cell apoptosis or necrosis, leading to plasma membrane alterations, and the occurrence of APA in response to sustained stimulation. The pathogenic potential of APA is also considered with respect to recurrent pregnancy loss.

  7. Genome-wide dynamics of alternative polyadenylation in rice

    Science.gov (United States)

    Fu, Haihui; Yang, Dewei; Su, Wenyue; Ma, Liuyin; Shen, Yingjia; Ji, Guoli; Ye, Xinfu; Wu, Xiaohui

    2016-01-01

    Alternative polyadenylation (APA), in which a transcript uses one of the poly(A) sites to define its 3′-end, is a common regulatory mechanism in eukaryotic gene expression. However, the potential of APA in determining crop agronomic traits remains elusive. This study systematically tallied poly(A) sites of 14 different rice tissues and developmental stages using the poly(A) tag sequencing (PAT-seq) approach. The results indicate significant involvement of APA in developmental and quantitative trait loci (QTL) gene expression. About 48% of all expressed genes use APA to generate transcriptomic and proteomic diversity. Some genes switch APA sites, allowing differentially expressed genes to use alternate 3′ UTRs. Interestingly, APA in mature pollen is distinct where differential expression levels of a set of poly(A) factors and different distributions of APA sites are found, indicating a unique mRNA 3′-end formation regulation during gametophyte development. Equally interesting, statistical analyses showed that QTL tends to use APA for regulation of gene expression of many agronomic traits, suggesting a potential important role of APA in rice production. These results provide thus far the most comprehensive and high-resolution resource for advanced analysis of APA in crops and shed light on how APA is associated with trait formation in eukaryotes. PMID:27733415

  8. 2015 Annual Report of the American Psychological Association.

    Science.gov (United States)

    2016-01-01

    Presents the 2015 Annual Report of the American Psychological Association. In his introduction, President Barry Anton describes how 2015 was among APA's most challenging. Although 2015 ushered in an era of greater transparency within the association and enhanced communications to members and the public, it also required painful self-reflection stemming from the revelations of an independent review by an outside law firm. The review examined the question of whether APA played any role related to the Bush administration's use of abusive interrogation techniques during the war on terror. Anton's introduction also discusses (1) the APA convention, (2) representing APA at a White House meeting with health care providers and insurance companies, (3) APA's effort to increase the number of APA-accredited internships, (4) international activities, and (5) the global summit on psychology and integrated care. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  9. Aminopeptidase A is a functional target in angiogenic blood vessels.

    Science.gov (United States)

    Marchiò, Serena; Lahdenranta, Johanna; Schlingemann, Reinier O; Valdembri, Donatella; Wesseling, Pieter; Arap, Marco A; Hajitou, Amin; Ozawa, Michael G; Trepel, Martin; Giordano, Ricardo J; Nanus, David M; Dijkman, Henri B P M; Oosterwijk, Egbert; Sidman, Richard L; Cooper, Max D; Bussolino, Federico; Pasqualini, Renata; Arap, Wadih

    2004-02-01

    We show that a membrane-associated protease, aminopeptidase A (APA), is upregulated and enzymatically active in blood vessels of human tumors. To gain mechanistic insight, we evaluated angiogenesis in APA null mice. We found that, although these mice develop normally, they fail to mount the expected angiogenic response to hypoxia or growth factors. We then isolated peptide inhibitors of APA from a peptide library and show that they specifically bind to and inhibit APA, suppress migration and proliferation of endothelial cells, inhibit angiogenesis, and home to tumor blood vessels. Finally, we successfully treated tumor-bearing mice with APA binding peptides or anti-APA blocking monoclonal antibodies. These data show that APA is a regulator of blood vessel formation, and can serve as a functional vascular target.

  10. Cell Cycle Regulation by Alternative Polyadenylation of CCND1.

    Science.gov (United States)

    Wang, Qiong; He, Guopei; Hou, Mengmeng; Chen, Liutao; Chen, Shangwu; Xu, Anlong; Fu, Yonggui

    2018-05-01

    Global shortening of 3'UTRs by alternative polyadenylation (APA) has been observed in cancer cells. However, the role of APA in cancer remains unknown. CCND1 is a proto-oncogene that regulates progression through the G1-S phase of the cell cycle; moreover, it has been observed to be switching to proximal APA sites in cancer cells. To investigate the biological function of the APA of CCND1, we edited the weak poly(A) signal (PAS) of the proximal APA site to a canonical PAS using the CRISPR/Cas9 method, which can force the cells to use a proximal APA site. Cell cycle profiling and proliferation assays revealed that the proximal APA sites of CCND1 accelerated the cell cycle and promoted cell proliferation, but UTR-APA and CR-APA act via different molecular mechanisms. These results indicate that PAS editing with CRISPR/Cas9 provides a good method by which to study the biological function of APA.

  11. Single Nucleotide Polymorphisms Can Create Alternative Polyadenylation Signals and Affect Gene Expression through Loss of MicroRNA-Regulation

    Science.gov (United States)

    Thomas, Laurent F.; Sætrom, Pål

    2012-01-01

    Alternative polyadenylation (APA) can for example occur when a protein-coding gene has several polyadenylation (polyA) signals in its last exon, resulting in messenger RNAs (mRNAs) with different 3′ untranslated region (UTR) lengths. Different 3′UTR lengths can give different microRNA (miRNA) regulation such that shortened transcripts have increased expression. The APA process is part of human cells' natural regulatory processes, but APA also seems to play an important role in many human diseases. Although altered APA in disease can have many causes, we reasoned that mutations in DNA elements that are important for the polyA process, such as the polyA signal and the downstream GU-rich region, can be one important mechanism. To test this hypothesis, we identified single nucleotide polymorphisms (SNPs) that can create or disrupt APA signals (APA-SNPs). By using a data-integrative approach, we show that APA-SNPs can affect 3′UTR length, miRNA regulation, and mRNA expression—both between homozygote individuals and within heterozygote individuals. Furthermore, we show that a significant fraction of the alleles that cause APA are strongly and positively linked with alleles found by genome-wide studies to be associated with disease. Our results confirm that APA-SNPs can give altered gene regulation and that APA alleles that give shortened transcripts and increased gene expression can be important hereditary causes for disease. PMID:22915998

  12. The Anti-Inflammatory Actions of Auricular Point Acupressure for Chronic Low Back Pain

    Directory of Open Access Journals (Sweden)

    Wei-Chun Lin

    2015-01-01

    Full Text Available Background. Auricular point acupressure (APA is a promising treatment for pain management. Few studies have investigated the physiological mechanisms of APA analgesics. Method. In this pilot randomized clinical trial (RCT, a 4-week APA treatment was used to manage chronic low back pain (CLBP. Sixty-one participants were randomized into a real APA group (n=32 or a sham APA group (n=29. Blood samples, pain intensity, and physical function were collected at baseline and after 4 weeks of treatment. Results. Subjects in the real APA group reported a 56% reduction of pain intensity and a 26% improvement in physical function. Serum blood samples showed (1 a decrease in IL-1β, IL-2, IL-6, and calcitonin gene-related peptide [CGRP] and (2 an increase in IL-4. In contrast, subjects in the sham APA group (1 reported a 9% reduction in pain and a 2% improvement in physical function and (2 exhibited minimal changes of inflammatory cytokines and neuropeptides. Statistically significant differences in IL-4 and CGRP expression between the real and sham APA groups were verified. Conclusion. These findings suggest that APA treatment affects pain intensity through modulation of the immune system, as reflected by APA-induced changes in serum inflammatory cytokine and neuropeptide levels.

  13. Sparse Adaptive Channel Estimation Based on lp-Norm-Penalized Affine Projection Algorithm

    Directory of Open Access Journals (Sweden)

    Yingsong Li

    2014-01-01

    Full Text Available We propose an lp-norm-penalized affine projection algorithm (LP-APA for broadband multipath adaptive channel estimations. The proposed LP-APA is realized by incorporating an lp-norm into the cost function of the conventional affine projection algorithm (APA to exploit the sparsity property of the broadband wireless multipath channel, by which the convergence speed and steady-state performance of the APA are significantly improved. The implementation of the LP-APA is equivalent to adding a zero attractor to its iterations. The simulation results, which are obtained from a sparse channel estimation, demonstrate that the proposed LP-APA can efficiently improve channel estimation performance in terms of both the convergence speed and steady-state performance when the channel is exactly sparse.

  14. Independence of scientific publishing. Reaffirming the principle.

    Science.gov (United States)

    Bjork, R A

    2000-09-01

    Historically, the American Psychological Association (APA), as part of its contract with the editors of APA journals, has granted to the editors sole responsibility to accept or reject manuscripts for publication, without such actions being open for review by APA. Such a policy fosters the freedom of inquiry and expression so necessary for a healthy science. It also serves to protect the Association because publication of an article in an APA journal does not represent endorsement by APA itself. The lessons of history are clear: When political or other pressures interfere with the autonomy of science, the societal and scientific consequences are grim. APA should reaffirm the principle that a healthy science of psychology requires an open exchange of ideas and findings.

  15. Out of mind - out of sight : studies on clinical and psychophysiological characteristics of dissociative identity disorder

    OpenAIRE

    Dale, Karl Yngvar

    2008-01-01

    Dissociative identity disorder (DID; APA, 1994), previously labeled Multiple personality (APA, 1980) and Multiple Personality Disorder (APA, 1987), has good diagnostic validity (Gleaves, May, & Cardeña, 2001) and is supported by taxometric research, whereby two types of dissociation have been identified: Pathological dissociation, whose features are consistent with DID, and nonpathological dissociation (Waller, Putnam, & Carlson, 1996). On these grounds, we aimed to contribute to a further...

  16. Kajian Hukum Tentang Kejahatan Pencurian Beras Kopi Dengan Pemberatan (Studi Kasus di Kabupaten Kerinci)

    OpenAIRE

    Wahyunita

    2008-01-01

    Skripsi ini berjudul "KAJIAN HUKUM TENTANG KEJAHATAN PENCURIAN BERAS KOPI DENGAN PEMBERATAN ( Studi Kasus Di Kabupaten Kerinci )", ada beberapa permasalahan yang diteliti dalam penulisan skripsi ini yaitu : faktor-faktor apa yang menyebabkan terjadinya kejahatan peneurian dengan pemberatan di Kabupaten Kerinci, usaha-usaha apa yang digunakan dalam menanggulangi kejahatan peneurian dengan pemberatan di Kabupaten Kerinci serta hambatan-hambatan apa saja yang dihadapi dalam usaha menanggulangi k...

  17. The Role of Proprioception in the Sagittal Setting of Anticipatory Postural Adjustments During Gait Initiation

    OpenAIRE

    Pereira Marcelo P.; Pelicioni Paulo H. Silva; Gobbi Lilian T.B.

    2015-01-01

    Purpose. Previous studies have studied the role of proprioception on the setting of anticipatory postural adjustments (APA) during gait initiation. However, these studies did not investigate the role of proprioception in the sagittal APA setting. We aimed to investigate the role of proprioception manipulation to induce APA sagittal adaptations on gait initiation. Methods. Fourteen healthy adults performed gait initiation without, and with, vibration applied before movement onset, and during m...

  18. A mannequin study of intubation with the AP advance and GlideScope Ranger videolaryngoscopes and the Macintosh laryngoscope.

    Science.gov (United States)

    Hodd, Jack A R; Doyle, D John; Gupta, Shipra; Dalton, Jarrod E; Cata, Juan P; Brewer, Edward J; James, Monyulona; Sessler, Daniel I

    2011-10-01

    The AP Advance (APA) is a videolaryngoscope with interchangeable blades: intubators can choose standard Macintosh blades or a difficult-airway blade with increased curvature and a channel to guide the tube to the larynx. The APA may therefore be comparably effective in both normal and difficult airways. We tested the hypotheses that intubation with the APA is no slower than Macintosh laryngoscopy for normal mannequin airways, and that it is no slower than videolaryngoscopy using a GlideScope Ranger in difficult mannequin airways. Medical professionals whose roles potentially include tracheal intubation were trained with each device. Participants intubated simulated (Laerdal SimMan) normal and difficult airways with the APA, GlideScope, and a conventional Macintosh blade. Speed of intubation was compared using Cox proportional hazards regression, with a hazard ratio >0.8 considered noninferior. We also compared laryngeal visualization, failures, and participant preferences. Unadjusted intubation times in the normal airway with the APA and Macintosh were virtually identical (median, 22 vs 23 seconds); after adjustment for effects of experience, order, and period, the hazard ratio (95% confidence interval) comparing APA with Macintosh laryngoscopy was 0.87 (0.65, 1.17), which was not significantly more than our predefined noninferiority boundary of 0.8 (P = 0.26). Intubation with the APA was faster than with the GlideScope in difficult airways (hazard ratio = 7.6 [5.0, 11.3], P APA, whereas 33% and 37% failed with the GlideScope and Macintosh, respectively. In the difficult airway, 99% of participants achieved a Cormack and Lehane grade I to II view with the APA, versus 85% and 33% with the GlideScope and Macintosh, respectively. When asked to choose 1 device overall, 82% chose the APA. Intubation times were similar with the APA and Macintosh laryngoscopes in mannequins with normal airways. However, intubation with the APA was significantly faster than with the Glide

  19. Amplexicaule A exerts anti-tumor effects by inducing apoptosis in human breast cancer

    OpenAIRE

    Xiang, Meixian; Su, Hanwen; Shu, Guangwen; Wan, Dingrong; He, Feng; Loaec, Morgann; Ding, Yali; Li, Jun; Dovat, Sinisa; Yang, Gaungzhong; Song, Chunhua

    2016-01-01

    Chemotherapy is the main treatment for patients with breast cancer metastases, but natural alternatives have been receiving attention for their potential as novel anti-tumor reagents. Amplexicaule A (APA) is a flavonoid glucoside isolated from rhizomes of Polygonum amplexicaule D. Don var. sinense Forb (PADF). We found that APA has anti-tumor effects in a breast cancer xenograft mouse model and induces apoptosis in breast cancer cell lines. APA increased levels of cleaved caspase-3,-8,-9 and ...

  20. Asymmetry of Anticipatory Postural Adjustment During Gait Initiation

    OpenAIRE

    Hiraoka, Koichi; Hatanaka, Ryota; Nikaido, Yasutaka; Jono, Yasutomo; Nomura, Yoshifumi; Tani, Keisuke; Chujo, Yuta

    2014-01-01

    The purpose of this study was to investigate the asymmetry of anticipatory postural adjustment (APA) during gait initiation and to determine whether the process of choosing the initial swing leg affects APA during gait initiation. The participants initiated gait with the leg indicated by a start tone or initiated gait with the leg spontaneously chosen. The dependent variables of APA were not significantly different among the condition of initiating gait with the preferred leg indicated by the...

  1. Characterization of mTOR-Responsive Truncated mRNAs in Cell Proliferation

    Science.gov (United States)

    2017-07-01

    These findings identify a previously uncharacterized role for mTOR in modulating 3’- UTR length of mRNAs by alternative polyadenylation ( APA ). Another...outcome of APA in the mTOR-activated transcriptome is an early termination of mRNA transcription to produce truncated mRNAs with polyadenylation in...for exhaustive analysis of Alternative cleavage and polyadenylation ( APA ) events (Figure 1). In IntMAP, first the position of multiple

  2. Case Report: Nodule Development From Subcapsular Aldosterone-Producing Cell Clusters Causes Hyperaldosteronism.

    Science.gov (United States)

    Nishimoto, Koshiro; Seki, Tsugio; Kurihara, Isao; Yokota, Kenichi; Omura, Masao; Nishikawa, Tetsuo; Shibata, Hirotaka; Kosaka, Takeo; Oya, Mototsugu; Suematsu, Makoto; Mukai, Kuniaki

    2016-01-01

    We previously reported that the human adrenal cortex remodels to form subcapsular aldosterone-producing cell clusters (APCCs). Some APCCs were recently found to carry aldosterone-producing adenoma (APA)-associated somatic mutations in ion channel/pump genes, which implied that APCCs produce aldosterone autonomously and are an origin of APA. However, there has been no report describing an APCC-to-APA transitional lesion. A histological examination revealed unilateral multiple adrenocortical micronodules in the adrenals of two patients with primary aldosteronism (PA). Based on immunohistochemistry for aldosterone synthase, some of the micronodules were identified as possible APCC-to-APA transitional lesions (pAATLs; a tentative term used in this manuscript), which consisted of a subcapsular APCC-like portion and an inner micro-APA-like (mAPA-like) portion without an apparent histological border. Genomic DNA samples prepared from pAATL histological sections were analyzed by next-generation sequencing for the known APA-associated mutations. The mAPA-like portions from two of the three large pAATLs examined harbored mutations (KCNJ5 [p.G151R] in pAATL 3 and ATP1A1 [p.L337M] in pAATL 7), whereas their corresponding APCC-like portions did not, suggesting their role in the formation of mAPA. Another lesion carried novel mutations in ATP1A1 (p.Ile322_Ile325del and p.Ile327Ser) in both the mAPA-like and APCC-like portions, thereby supporting these portions having a clonal origin. A novel aldosterone-producing pathology, pAATL that causes unilateral PA, was detected in the adrenals of two patients. Next-generation sequencing analyses of the large pAATLs suggested that the introduction of APA-associated mutations in the ion channel/pump genes may be involved in the development of mAPA from existing APCCs.

  3. The Economics of Advance Pricing Agreements

    OpenAIRE

    Johannes Becker; Ronald B. Davies; Gitte Jakobs

    2014-01-01

    Advance pricing agreements (APAs) determine transfer prices for intra-firm transactions in advance. This paper interprets these contracts as a means to overcome a hold-up problem that occurs because governments cannot commit to non-excessive future tax rates. In addition, with private information, just as in practice, our APAs will be complex and require lengthy negotiations. Never- theless, implemented APAs lead to a Pareto improvement even when all agents are risk neutral. However, not all ...

  4. Subcellular RNA profiling links splicing and nuclear DICER1 to alternative cleavage and polyadenylation.

    Science.gov (United States)

    Neve, Jonathan; Burger, Kaspar; Li, Wencheng; Hoque, Mainul; Patel, Radhika; Tian, Bin; Gullerova, Monika; Furger, Andre

    2016-01-01

    Alternative cleavage and polyadenylation (APA) plays a crucial role in the regulation of gene expression across eukaryotes. Although APA is extensively studied, its regulation within cellular compartments and its physiological impact remains largely enigmatic. Here, we used a rigorous subcellular fractionation approach to compare APA profiles of cytoplasmic and nuclear RNA fractions from human cell lines. This approach allowed us to extract APA isoforms that are subjected to differential regulation and provided us with a platform to interrogate the molecular regulatory pathways that shape APA profiles in different subcellular locations. Here, we show that APA isoforms with shorter 3' UTRs tend to be overrepresented in the cytoplasm and appear to be cell-type-specific events. Nuclear retention of longer APA isoforms occurs and is partly a result of incomplete splicing contributing to the observed cytoplasmic bias of transcripts with shorter 3' UTRs. We demonstrate that the endoribonuclease III, DICER1, contributes to the establishment of subcellular APA profiles not only by expected cytoplasmic miRNA-mediated destabilization of APA mRNA isoforms, but also by affecting polyadenylation site choice. © 2016 Neve et al.; Published by Cold Spring Harbor Laboratory Press.

  5. Biaxial and antiferroelectric structure of the orthogonal smectic phase of a bent-shaped molecule and helical structure in a chiral mixture system

    Science.gov (United States)

    Kang, Sungmin; Nguyen, Ha; Nakajima, Shunpei; Tokita, Masatoshi; Watanabe, Junji

    2013-05-01

    We examined the biaxial and antiferroelectric properties in the Smectic-APA (Sm-APA) phase of bent-shaped DC-S-8. The biaxiality, which results from the existence of a secondary director, was well established from birefringence observations in the homeotropically aligned Sm-APA. By entering into Sm-APA phase, the birefringence (Δn, difference between two refractive indices of short axes) continuously increased from 0 to 0.02 with decreasing temperature. The antiferroelectric switching and second harmonic generation (SHG) activity on the field-on state were also observed in the Sm-APA phase, and the evaluated spontaneous polarization (PS) value strongly depended on temperature. The temperature dependence of Δn and PS resembles each other and follows Haller's approximation, showing that the biaxiality is due to polar packing in which the molecules are preferentially packed with their bent direction arranged in the same direction, and that the phase transition of Sm-APA to Sm-A is second order. The biaxiality was further examined in chiral Sm-APA*. Doping with chiral components induced the helical twisting of the secondary director in the Sm-APA* phase, which was confirmed by observing the reflection of the circular dichroism (CD) bands in the homeotropically aligned cell. The helical pitch of Sm-APA* is tunable in the range of 300-700 nm wavelength with a variation in the chiral content of 5 to 10 weight (wt)%.

  6. Low complexity adaptive equalizers for underwater acoustic communications

    Science.gov (United States)

    Soflaei, Masoumeh; Azmi, Paeiz

    2014-08-01

    Interference signals due to scattering from surface and reflecting from bottom is one of the most important problems of reliable communications in shallow water channels. To solve this problem, one of the best suggested ways is to use adaptive equalizers. Convergence rate and misadjustment error in adaptive algorithms play important roles in adaptive equalizer performance. In this paper, affine projection algorithm (APA), selective regressor APA(SR-APA), family of selective partial update (SPU) algorithms, family of set-membership (SM) algorithms and selective partial update selective regressor APA (SPU-SR-APA) are compared with conventional algorithms such as the least mean square (LMS) in underwater acoustic communications. We apply experimental data from the Strait of Hormuz for demonstrating the efficiency of the proposed methods over shallow water channel. We observe that the values of the steady-state mean square error (MSE) of SR-APA, SPU-APA, SPU-normalized least mean square (SPU-NLMS), SPU-SR-APA, SM-APA and SM-NLMS algorithms decrease in comparison with the LMS algorithm. Also these algorithms have better convergence rates than LMS type algorithm.

  7. Simple method for preparation of secondary amides of phosphorylacetic acids and their use for actinide extraction and sorption from nitric acid solutions

    International Nuclear Information System (INIS)

    Artyushin, O.I.; Sharova, E.V.; Odinets, I.L.; Lenevich, S.V.; Mastruykova, T.A.; Morgalyuk, V.P.; Tananaev, I.G.; Pribylova, G.V.; Myasoedova, G.V.; Myasoedov, B.F.

    2004-01-01

    An effective method of synthesis of secondary alkylamides of phosphorylacetic acids (APA), based on amidation of ethyl esters of phosphorylacetic acids with primary aliphatic amines, was developed. Extraction of americium(III) complexes with APA solutions in dichloroethane and uranium(VI) sorption by sorbents with non-covalently fixed APA from nitric acid solutions were studied. In the course of americium(III) extraction there is no correlation between Am III distribution factor and APA structure, whereas during uranium(VI) sorption a dependence of U VI extraction degree on the complexing agent structure is observed [ru

  8. 2012 Annual report of the American Psychological Association.

    Science.gov (United States)

    2013-01-01

    Provides the 2012 Annual Report of the American Psychological Association. In 2012, APA celebrated its 120th anniversary. It has grown from its original 31 members to the largest association of psychologists in the United States and a worldwide leader within the discipline. This edition of the report introduces each directorate and office within APA and talks about their goals and objectives. the president of APA, Dr. Norman Anderson, also gives a brief report which updates you on the activities of the association during its 120th anniversary as the professional home for psychologists and an advocate for the discipline. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  9. In vivo antibody-mediated modulation of aminopeptidase A in mouse proximal tubular epithelial cells.

    Science.gov (United States)

    Mentzel, S; Dijkman, H B; van Son, J P; Wetzels, J F; Assmann, K J

    1999-07-01

    Aminopeptidase A (APA) is one of the many renal hydrolases. In mouse kidney, APA is predominantly expressed on the brush borders and sparsely on the basolateral membranes of proximal tubular epithelial cells. However, when large amounts of monoclonal antibodies (MAbs) against APA were injected into mice, we observed strong binding of the MAbs to the basolateral membranes, whereas the MAbs bound only transiently to the brush borders of the proximal tubular epithelial cells. In parallel, APA itself disappeared from the brush borders by both endocytosis and shedding, whereas it was increasingly expressed on the basolateral sides. Using ultrastructural immunohistology, we found no evidence for transcellular transport of endocytosed APA to the basolateral side of the proximal tubular epithelial cells. The absence of transcellular transport was confirmed by experiments in which we used a low dose of the MAbs. Such a low dose did not result in binding of the MAbs to the brush borders and had no effect on the presence of APA in the brush borders of the proximal tubular epithelial cells. In these experiments we still could observe binding of the MAbs to the basolateral membranes in parallel with the local appearance of APA. In addition, treatment of mice with chlorpromazine, a calmodulin antagonist that interferes with cytoskeletal function, largely inhibited the MAb-induced modulation of APA. Our studies suggest that injection of MAbs to APA specifically interrupts the normal intracellular traffic of this enzyme in proximal tubular epithelial cells. This intracellular transport is dependent on the action of cytoskeletal proteins.

  10. What Is Psychiatry?

    Medline Plus

    Full Text Available ... diagnoses are based on criteria established in APA's Diagnostic and Statistical Manual of Mental Disorders ( DSM-5 ), which contains descriptions, symptoms and other criteria ...

  11. Theory of affine projection algorithms for adaptive filtering

    CERN Document Server

    Ozeki, Kazuhiko

    2016-01-01

    This book focuses on theoretical aspects of the affine projection algorithm (APA) for adaptive filtering. The APA is a natural generalization of the classical, normalized least-mean-squares (NLMS) algorithm. The book first explains how the APA evolved from the NLMS algorithm, where an affine projection view is emphasized. By looking at those adaptation algorithms from such a geometrical point of view, we can find many of the important properties of the APA, e.g., the improvement of the convergence rate over the NLMS algorithm especially for correlated input signals. After the birth of the APA in the mid-1980s, similar algorithms were put forward by other researchers independently from different perspectives. This book shows that they are variants of the APA, forming a family of APAs. Then it surveys research on the convergence behavior of the APA, where statistical analyses play important roles. It also reviews developments of techniques to reduce the computational complexity of the APA, which are important f...

  12. 75 FR 60333 - Hazardous Material; Miscellaneous Packaging Amendments

    Science.gov (United States)

    2010-09-30

    ..., which is contrary to the Administrative Procedure Act (APA). They also state under the revised... General requirements. * * * * * (g) * * * (8) * * * (xiii) * * * (C) Closure ring style including bolt...

  13. What Is Psychiatry?

    Medline Plus

    Full Text Available ... Values, and Goals Meet Our Organization Read APA Organization Documents and Policies Work at ... Competency Awards & Leadership Opportunities Advocacy & APAPAC Meetings Search ...

  14. Collusion, torture, and inequality: Understanding the actions of the American Psychological Association as institutional betrayal.

    Science.gov (United States)

    Gómez, Jennifer M; Smith, Carly P; Gobin, Robyn L; Tang, Shin Shin; Freyd, Jennifer J

    2016-01-01

    The Hoffman Report (Hoffman et al., 2015) documented devastating information about the American Psychological Association (APA) and the profession of psychology in the United States, prompting a public apology and a formal commitment by APA to correct its mistakes (APA, 2015). In the current article, we utilize betrayal trauma theory (Freyd, 1997), including betrayal blindness (e.g., Freyd, 1996; Tang, 2015) and institutional betrayal (Smith & Freyd, 2014b), to understand and learn from APA's behaviors. We further situate this discussion in the context of inequality, both within APA and in American society generally. We detail how the impact of APA's institutional betrayals extended beyond the organization, its members, and the psychology profession, highlighting the potential for disproportionate harm to minorities, including those who were tortured; Muslims, Middle Easterners, Afghans, and non-Americans who were not tortured; and other minority individuals (Gómez, 2015d). Acknowledging, understanding, and addressing its institutional betrayals offers APA the opportunity to take meaningful corrective and preventive measures. We propose several institutional reparations, including making concrete changes with transparency and conducting self-assessments to inform further needed changes (Freyd & Birrell, 2013). By engaging in institutional courage, APA has the potential to grow into an ethical governing body that fulfills its mission to "advance the creation, communication and application of psychological knowledge to benefit society and improve people's lives" (APA, 2016).

  15. [Physical exercise for people with cerebral palsy: effects, recommendations and barriers].

    Science.gov (United States)

    Barak, Sharon; Hutzler, Yeshayahu; Dubnov-Raz, Gal

    2014-05-01

    The management goal of cerebral palsy (CP) is improving functionality, locomotion and independence. Treatment programs commonly encompass adapted physical activity (APA). This review summarizes the knowledge regarding the effects and recommendations for APA in persons with CP. In addition, barriers to APA in this population are reviewed. The available literature on benefits of APA to persons with CP has focused mainly on youth. The components of the APA programs generally consist of strength, aerobic and flexibility training. There is no empirical evidence that strength-training increases spasticity in people with CP. Furthermore, strength-training may increase strength and the ability to perform daily activities. Aerobic-training is especially important as persons with CP typically have low cardiorespiratory fitness and high prevalence of cardiac disease. However, limited published evidence exists on aerobic-training effects in this population. Nonetheless, the evidence suggests that aerobic-training in persons with CP can improve physiological outcomes, yet the influence of these changes on participation has not been investigated sufficiently. Stretching exercise is a common treatment for spasticity. Surprisingly, there is inconclusive evidence for the effectiveness of stretching exercise for persons with CP. Despite the importance attributed to APA for people with CP, low levels of physical activity have been reported in this population. However, when caregivers perceive greater benefits of exercise, individuals with CP are more likely to be active. In contrast, barriers to APA include costs of APA programs, limited means of transportation to APA facilities, lack of information regarding APA facilities and limited appropriate exercising equipment in the APA facilities.

  16. Deficiency of the Angiotensinase Aminopeptidase A Increases Susceptibility to Glomerular Injury.

    Science.gov (United States)

    Velez, Juan Carlos Q; Arif, Ehtesham; Rodgers, Jessalyn; Hicks, Megan P; Arthur, John M; Nihalani, Deepak; Bruner, Evelyn T; Budisavljevic, Milos N; Atkinson, Carl; Fitzgibbon, Wayne R; Janech, Michael G

    2017-07-01

    Aminopeptidase A (APA) is expressed in glomerular podocytes and tubular epithelia and metabolizes angiotensin II (AngII), a peptide known to promote glomerulosclerosis. In this study, we tested whether APA expression changes in response to progressive nephron loss or whether APA exerts a protective role against glomerular damage and during AngII-mediated hypertensive kidney injury. At advanced stages of FSGS, fawn-hooded hypertensive rat kidneys exhibited distinctly increased APA staining in areas of intact glomerular capillary loops. Moreover, BALB/c APA-knockout (KO) mice injected with a nephrotoxic serum showed persistent glomerular hyalinosis and albuminuria 96 hours after injection, whereas wild-type controls achieved virtually full recovery. We then tested the effect of 4-week infusion of AngII (400 ng/kg per minute) in APA-KO and wild-type mice. Although we observed no significant difference in achieved systolic BP, AngII-treated APA-KO mice developed a significant rise in albuminuria not observed in AngII-treated wild-type mice along with increased segmental and global sclerosis and/or collapse of juxtamedullary glomeruli, microcystic tubular dilation, and tubulointerstitial fibrosis. In parallel, AngII treatment significantly increased the kidney AngII content and attenuated the expression of podocyte nephrin in APA-KO mice but not in wild-type controls. These data show that deficiency of APA increases susceptibility to glomerular injury in BALB/c mice. The augmented AngII-mediated kidney injury observed in association with increased intrarenal AngII accumulation in the absence of APA suggests a protective metabolizing role of APA in AngII-mediated glomerular diseases. Copyright © 2017 by the American Society of Nephrology.

  17. 76 FR 59263 - Medicare Program; Hospital Inpatient Prospective Payment Systems for Acute Care Hospitals and the...

    Science.gov (United States)

    2011-09-26

    ... submission, we made an error in referencing the number of States in which healthcare associated infections... accordance with section 553(b) of the Administrative Procedure Act (APA) (5 U.S.C. 553(b)). However, we can... statement of the finding and the reasons therefore in the notice. Section 553(d) of the APA ordinarily...

  18. 78 FR 61197 - Medicare Program; Hospital Inpatient Prospective Payment Systems for Acute Care Hospitals and the...

    Science.gov (United States)

    2013-10-03

    ... typographical and technical errors in referencing an NQF-endorsed measure name. B. Summary of Errors in and... 553(b) of the Administrative Procedure Act (APA) (5 U.S.C. 553(b)). However, we can waive this notice... the reasons therefore in the notice. Section 553(d) of the APA ordinarily requires a 30-day delay in...

  19. the CORIS study

    African Journals Online (AJOL)

    main cause of death from circulatory disease among adults of all South African .... used to calculate LDLC (in mmoVl) for those participants . .... Table Ill. Medical history of CHO and its risk factors by apaS percentile categories. Men .... cholesterol and total energy expenditure, and BMI. ... very-low-density lipoprotein particles.

  20. 688,112 statistical results : Content mining psychology articles for statistical test results

    NARCIS (Netherlands)

    Hartgerink, C.H.J.

    2016-01-01

    In this data deposit, I describe a dataset that is the result of content mining 167,318 published articles for statistical test results reported according to the standards prescribed by the American Psychological Association (APA). Articles published by the APA, Springer, Sage, and Taylor & Francis

  1. 78 FR 54569 - Special Local Regulation, Cumberland River, Mile 190.0 to 192.0; Nashville, TN

    Science.gov (United States)

    2013-09-05

    ... comment pursuant to authority under section 4(a) of the Administrative Procedure Act (APA) (5 U.S.C. 553(b... APA, and immediate action is necessary to establish this special local regulation to protect... Security Management Directive 023-01 and Commandant Instruction M16475.lD, which guide the Coast Guard in...

  2. 78 FR 8407 - Endosulfan; Pesticide Tolerance

    Science.gov (United States)

    2013-02-06

    ... Classification System (NAICS) codes is not intended to be exhaustive, but rather provides a guide to help readers... adjudication and not a rule. Under the Administrative Procedures Act (APA), orders are expressly excluded from... the APA (5 U.S.C. 551(4)), and does not require the issuance of a proposed rule, the requirements of...

  3. 77 FR 36170 - TSCA Inventory Update Reporting Modifications; Chemical Data Reporting; 2012 Submission Period...

    Science.gov (United States)

    2012-06-18

    ... is not intended to be exhaustive, but rather provides a guide for readers regarding entities likely... U.S.C. 2607(a). Under section 553(b)(3)(B) of the Administrative Procedure Act (APA), 5 U.S.C. 553(b..., under APA section 553(d), 5 U.S.C. 553(d), the Agency may make a rule immediately effective ``for good...

  4. 77 FR 67568 - Regulated Navigation Area; East River, Flushing and Gowanus Bays, and Red Hook and Buttermilk...

    Science.gov (United States)

    2012-11-13

    .... SUPPLEMENTARY INFORMATION: Table of Acronyms APA Administrative Procedure Act DHS Department of Homeland... Administrative Procedure Act (APA) (5 U.S.C. 553). Section 553(b) provides that a general notice of proposed... Department of Homeland Security Management Directive 023-01 and Commandant Instruction M16475.lD, which guide...

  5. Ethical Issues in the Use of Humans for Research.

    Science.gov (United States)

    Bashaw, W. L.

    The APA Ethical Principles, the University of Georgia policy, standard research texts, and research literature on specific methodologies, all in relation to ethical issues in human research, are discussed. The 10 APA principles state, in essence, that the investigator is responsible for what happens, that confidentiality and the protection of the…

  6. 76 FR 27271 - TSCA Inventory Update Reporting Modifications; Submission Period Suspension

    Science.gov (United States)

    2011-05-11

    ... manufacturing). This listing is not intended to be exhaustive, but rather provides a guide for readers regarding... section 553 of the Administrative Procedure Act (APA), 5 U.S.C. 553, EPA is finalizing this action based... requirements). Alternatively, under section 553(b)(3)(B) of the APA, the Agency may issue a final rule without...

  7. 78 FR 63892 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Science.gov (United States)

    2013-10-25

    .../13monkeia.html . Copies of the small entity compliance guide are available at the following internet address... Procedure Act (APA). Pursuant to section 305(c)(3)(B) of the Magnuson-Stevens Act, management measures... APA. Comments and Responses Fifteen comments were received during the public comment period on the...

  8. 78 FR 52987 - Entergy Nuclear Operations, Inc., Indian Point Nuclear Generating Unit 3

    Science.gov (United States)

    2013-08-27

    ... of the Administrative Procedure Act (APA), the Atomic Energy Act (AEA), or the National Environmental... fire hazards and combustibles, automatic cable tray fire suppression system, manual fire suppression... recently rejected the argument that the AEA or the APA requires the NRC to hold a hearing on granting an...

  9. 77 FR 29696 - James Edgar Lundeen, Sr., M.D.; Dismissal of Proceeding

    Science.gov (United States)

    2012-05-18

    .... \\2\\ In accordance with the Administrative Procedure Act (APA), an agency ``may take official notice... General's Manual on the Administrative Procedure Act 80 (1947) (Wm. W. Gaunt & Sons, Inc., Reprint 1979). In accordance with the APA and DEA's regulations, Respondent is ``entitled on timely request to an...

  10. 76 FR 18365 - Fair Credit Reporting Act and Bank Secrecy Act Compliance

    Science.gov (United States)

    2011-04-04

    ... Procedure Act (APA), an agency may, for good cause, find (and incorporate the finding and a brief statement... and comment procedures prescribed by the APA are unnecessary because the final rule makes technical... Asked Questions, and the FFIEC Bank Secrecy Act/Anti-Money Laundering Examination Manual. (iii...

  11. 75 FR 71638 - Safety Zone; Fleet Week Maritime Festival, Pier 66, Elliot Bay, Seattle, WA

    Science.gov (United States)

    2010-11-24

    ... Procedure Act (APA) to request public comment and publicize this regulation through all required avenues... COMDINST M5728.2D. COMDINST M5728.2D is the Coast Guard Public Affairs Manual intended to provide non.... This regulation was published in accordance with the Administrative Procedure Act (APA) in the Federal...

  12. Tobacco industry influence on the definition of tobacco related disorders by the American Psychiatric Association

    OpenAIRE

    Neuman, M; Bitton, A; Glantz, S

    2005-01-01

    Objective: The Diagnostic and statistical manual of mental disorders, third edition (DSM-III), published by the American Psychiatric Association (APA) in 1980, included the first official definitions by the APA of tobacco dependence and tobacco withdrawal. Tobacco industry efforts to influence the DSM-III were investigated.

  13. Anticipatory postural adjustment patterns during gait initiation across the adult lifespan.

    Science.gov (United States)

    Lu, Chiahao; Amundsen Huffmaster, Sommer L; Harvey, Jack C; MacKinnon, Colum D

    2017-09-01

    Gait initiation involves a complex sequence of anticipatory postural adjustments (APAs) during the transition from steady state standing to forward locomotion. APAs have four core components that function to accelerate the center of mass forwards and towards the initial single-support stance limb. These components include loading of the initial step leg, unloading of the initial stance leg, and excursion of the center of pressure in the posterior and lateral (towards the stepping leg) directions. This study examined the incidence, magnitude, and timing of these components and how they change across the lifespan (ages 20-79). 157 individuals performed five trials of self-paced, non-cued gait initiation on an instrumented walkway. At least one component of the APA was absent in 24% of all trials. The component most commonly absent was loading of the initial step leg (absent in 10% of all trials in isolation, absent in 10% of trials in conjunction with another missing component). Trials missing all four components were rare (1%) and were observed in both younger and older adults. There was no significant difference across decades in the incidence of trials without an APA, the number or type of APA components absent, or the magnitude or timing of the APA components. These data demonstrate that one or more components of the APA sequence are commonly absent in the general population and the spatiotemporal profile of the APA does not markedly change with ageing. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Ethics as an Undergraduate Psychology Outcome: When, Where, and How to Teach It

    Science.gov (United States)

    Ruiz, Ana; Warchal, Judith

    2014-01-01

    The American Psychological Association (APA) recently approved a new set of "Guidelines for the undergraduate psychology major, version 2.0" (APA, 2013a) which addressed ethics specifically. Yet the teaching of ethics receives little attention in publications, national and international institutes, and conferences. Few guidelines for…

  15. Reporting and Interpreting Effect Size in Quantitative Agricultural Education Research

    Science.gov (United States)

    Kotrlik, Joe W.; Williams, Heather A.; Jabor, M. Khata

    2011-01-01

    The Journal of Agricultural Education (JAE) requires authors to follow the guidelines stated in the Publication Manual of the American Psychological Association [APA] (2009) in preparing research manuscripts, and to utilize accepted research and statistical methods in conducting quantitative research studies. The APA recommends the reporting of…

  16. Animated Pedagogical Agents Effects on Enhancing Student Motivation and Learning in a Science Inquiry Learning Environment

    Science.gov (United States)

    van der Meij, Hans; van der Meij, Jan; Harmsen, Ruth

    2015-01-01

    This study focuses on the design and testing of a motivational animated pedagogical agent (APA) in an inquiry learning environment on kinematics. The aim of including the APA was to enhance students' perceptions of task relevance and self-efficacy. Given the under-representation of girls in science classrooms, special attention was given to…

  17. Exploratory Study of Asian Pacific American Female Leaders in Higher Education

    Science.gov (United States)

    Mella, Hazel Roca

    2012-01-01

    The purpose of this study was to determine if and to what extent the model minority myth prevents "Asian Pacific American" ("APA") women from achieving the president or chancellor position in higher education institutions. This study explored the experiences of APA female leaders who are presidents and chancellors to discover…

  18. Fip1 regulates mRNA alternative polyadenylation to promote stem cell self-renewal

    Science.gov (United States)

    Lackford, Brad; Yao, Chengguo; Charles, Georgette M; Weng, Lingjie; Zheng, Xiaofeng; Choi, Eun-A; Xie, Xiaohui; Wan, Ji; Xing, Yi; Freudenberg, Johannes M; Yang, Pengyi; Jothi, Raja; Hu, Guang; Shi, Yongsheng

    2014-01-01

    mRNA alternative polyadenylation (APA) plays a critical role in post-transcriptional gene control and is highly regulated during development and disease. However, the regulatory mechanisms and functional consequences of APA remain poorly understood. Here, we show that an mRNA 3′ processing factor, Fip1, is essential for embryonic stem cell (ESC) self-renewal and somatic cell reprogramming. Fip1 promotes stem cell maintenance, in part, by activating the ESC-specific APA profiles to ensure the optimal expression of a specific set of genes, including critical self-renewal factors. Fip1 expression and the Fip1-dependent APA program change during ESC differentiation and are restored to an ESC-like state during somatic reprogramming. Mechanistically, we provide evidence that the specificity of Fip1-mediated APA regulation depends on multiple factors, including Fip1-RNA interactions and the distance between APA sites. Together, our data highlight the role for post-transcriptional control in stem cell self-renewal, provide mechanistic insight on APA regulation in development, and establish an important function for APA in cell fate specification. PMID:24596251

  19. CASE REPORT CASE CASE Conned by Conn's syndrome

    African Journals Online (AJOL)

    2008-01-08

    Jan 8, 2008 ... ing of the aldosterone-producing adenoma (APA) can prove challenging but is nonetheless very important for surgical planning and cure. We present two patients with MRI (magnetic resonance imaging) confirma- tion of APA with negative and equivocal CT (computed tomography) scans. Case 1.

  20. 77 FR 6681 - Approval and Promulgation of State Plans for Designated Facilities and Pollutants; State of...

    Science.gov (United States)

    2012-02-09

    ... (APA) which, upon finding ``good cause,'' authorizes agencies to dispense with public participation.... EPA also finds that there is good cause under APA section 553(d)(3) for this correction to become effective on the date of publication of this action. [[Page 6682

  1. Difference, Adapted Physical Activity and Human Development: Potential Contribution of Capabilities Approach

    Science.gov (United States)

    Silva, Carla Filomena; Howe, P. David

    2012-01-01

    This paper is a call to Adapted Physical Activity (APA) professionals to increase the reflexive nature of their practice. Drawing upon Foucault's concept of governmentality (1977) APA action may work against its own publicized goals of empowerment and self-determination. To highlight these inconsistencies, we will draw upon historical and social…

  2. Self-Efficacy and Preparation of Scholarly Writing: Online Doctoral Coursework to Comprehensive Examination--a Mixed Method Study

    Science.gov (United States)

    Thomas, Sonya C.

    2013-01-01

    Writing is seldom explicitly taught, most specifically, in academic and scholarly writing. Therefore, this mixed methods correlational phenomenology research study explored the correlation between self-efficacy perception and course room preparation for the comprehensive examination, APA standards in the course room, APA standards evaluation for…

  3. Microarray Meta-Analysis of RNA-Binding Protein Functions in Alternative Polyadenylation

    Science.gov (United States)

    Hu, Wenchao; Liu, Yuting; Yan, Jun

    2014-01-01

    Alternative polyadenylation (APA) is a post-transcriptional mechanism to generate diverse mRNA transcripts with different 3′UTRs from the same gene. In this study, we systematically searched for the APA events with differential expression in public mouse microarray data. Hundreds of genes with over-represented differential APA events and the corresponding experiments were identified. We further revealed that global APA differential expression occurred prevalently in tissues such as brain comparing to peripheral tissues, and biological processes such as development, differentiation and immune responses. Interestingly, we also observed widespread differential APA events in RNA-binding protein (RBP) genes such as Rbm3, Eif4e2 and Elavl1. Given the fact that RBPs are considered as the main regulators of differential APA expression, we constructed a co-expression network between APAs and RBPs using the microarray data. Further incorporation of CLIP-seq data of selected RBPs showed that Nova2 represses and Mbnl1 promotes the polyadenylation of closest poly(A) sites respectively. Altogether, our study is the first microarray meta-analysis in a mammal on the regulation of APA by RBPs that integrated massive mRNA expression data under a wide-range of biological conditions. Finally, we present our results as a comprehensive resource in an online website for the research community. PMID:24622240

  4. Joint effect of freshwater plume and coastal upwelling on phytoplankton growth off the Changjiang River

    Science.gov (United States)

    Tseng, Y.-F.; Lin, J.; Dai, M.; Kao, S.-J.

    2014-01-01

    The Changjiang (Yangtze) River discharges vast amount of unbalanced nutrients (dissolved inorganic nitrogen and phosphorus with N / P ratio > 80 in general) into the East China Sea in summer. To study nutrient dynamics and P-stress potential for phytoplankton, a cruise was conducted in the Changjiang plume during summer 2011. With 3-D observations of nutrients, chlorophyll a (Chl a), and bulk alkaline phosphatase activity (APA), we concluded that the Changjiang Diluted Water and coastal upwelling significantly influenced the horizontal and vertical heterogeneities of phytoplankton P deficiency in the Changjiang plume. Allochthonous APA was detected at nutrient-enriched freshwater end. Excessive N (~ 10 to 112 μM) was observed throughout the entire plume surface. In the plume fringe featuring stratification and excess N, diapycnal phosphate supply was blocked and phytoplankton APA was stimulated for growth. We observed an upwelling just attaching to the turbidity front at seaward side where Chl a peaked yet much less APA was detected. An external phosphate supply from subsurface, which promoted phytoplankton growth but inhibited APA, was suggested to be sourced from the Nearshore Kuroshio Branch Current. In the so hydrographically complicated Changjiang plume, phosphate supply instead of its concentration may be more important in determining the expression of APA. Meanwhile, allochthonous APA may also alter the usefulness of APA as a P-stress indicator.

  5. 76 FR 26186 - Multi-Walled Carbon Nanotubes; Significant New Use Rule

    Science.gov (United States)

    2011-05-06

    ... compatible with the Administrative Procedure Act (APA). EPA believes the procedures followed in developing this rule are consistent with the requirements in TSCA section 5(a)(2) and the APA. Comment 12: The PMN... that have been recently published in the peer-reviewed journals, Inhalation Toxicology, Toxicological...

  6. Reasons for Attending, Expected Obstacles, and Degree Aspirations of Asian Pacific American Community College Students

    Science.gov (United States)

    Wang, Winnie W.; Chang, June C.; Lew, Jonathan W.

    2009-01-01

    This study examined how the academic aspirations of Asian Pacific Americans (APAs) attending community colleges are influenced by their demographic and educational background, reasons for attending, and obstacles they expect to encounter. The sample consisted of 846 APAs out of a total student sample of 5,000 in an urban community college…

  7. Pedophilia and the Culture Wars.

    Science.gov (United States)

    Zuriff, G. E.

    2000-01-01

    Discusses reaction to research findings published in a journal of the American Psychological Association (APA) which concluded that classifying sexual behavior between adults and children as abuse merely because it is considered illegal or immoral, even in the absence of harm, is not scientifically valid. Notes the APA's stand on the study's…

  8. A Randomized Clinical Trial of Auricular Point Acupressure for Chronic Low Back Pain: A Feasibility Study

    Directory of Open Access Journals (Sweden)

    Chao Hsing Yeh

    2013-01-01

    Full Text Available Objectives. This prospective, randomized clinical trial (RCT was designed to investigate the feasibility and effects of a 4-week auricular point acupressure (APA for chronic low back pain (CLBP. Methods. Participants were randomized to either true APA (true acupoints with taped seeds on the designated ear points for CLBP or sham APA (sham acupoints with taped seeds but on different locations than those designated for CLBP. The duration of treatment was four weeks. Participants were assessed before treatment, weekly during treatment, and 1 month following treatment. Results. Participants in the true APA group who completed the 4-week APA treatment had a 70% reduction in worst pain intensity, a 75% reduction in overall pain intensity, and a 42% improvement in disability due to back pain from baseline assessment. The reductions of worst pain and overall pain intensity in the true APA group were statistically greater than participants in the sham group (P<0.01 at the completion of a 4-week APA and 1 month followup. Discussion. The preliminary findings of this feasibility study showed a reduction in pain intensity and improvement in physical function suggesting that APA may be a promising treatment for patients with CLBP.

  9. Developing a Taxonomy of Helpful and Harmful Practices for Clinical Work with Boys and Men

    Science.gov (United States)

    Mahalik, James R.; Good, Glenn E.; Tager, David; Levant, Ronald F.; Mackowiak, Christopher

    2012-01-01

    This study drew upon the knowledge base of member practitioners of the American Psychological Association (APA) to develop a taxonomy of helpful and harmful practices for treatment with boys and men. Four hundred seventy-five APA-member practitioners solicited from practice-related divisions provided responses to 4 open-ended questions about…

  10. Issues of College Persistence between Asian and Asian Pacific American Students

    Science.gov (United States)

    Yeh, Theresa Ling

    2004-01-01

    This article offers an exploration of the Asian Pacific American (APA) ethnic groups that show high rates of departure, and presents strategies and approaches to improving their persistence and graduation rates. A detailed examination of the APA population is presented to identify the subgroups that are underrepresented in higher education and who…

  11. Student Use of Animated Pedagogical Agents in a Middle School Science Inquiry Program

    Science.gov (United States)

    Bowman, Catherine D. D.

    2012-01-01

    Animated pedagogical agents (APAs) have the potential to provide one-on-one, just-in-time instruction, guidance or mentoring in classrooms where such individualized human interactions may be infeasible. Much current APA research focuses on a wide range of design variables tested with small samples or in laboratory settings, while overlooking…

  12. Caught in the Middle: Understanding Asian Pacific American Perspectives on Affirmative Action through Blumer's Group Position Theory.

    Science.gov (United States)

    Inkelas, Karen Kurotsuchi

    2003-01-01

    This study examines Asian Pacific American undergraduates' views on affirmative action and their perspectives on U.S. race relations through Herbert Blumer's (1958) theory of group position. Results indicate that Asian Pacific American (APA) students may perceive other minority student applicants as inferior to APA applicants and feel threatened…

  13. The Neglected 95%: Why American Psychology Needs to Become Less American

    Science.gov (United States)

    Arnett, Jeffrey J.

    2008-01-01

    This article proposes that psychological research published in APA journals focuses too narrowly on Americans, who comprise less than 5% of the world's population. The result is an understanding of psychology that is incomplete and does not adequately represent humanity. First, an analysis of articles published in six premier APA journals is…

  14. Animated pedagogical agents effects on enhancing student motivation and learning in a science inquiry learning environment

    NARCIS (Netherlands)

    van der Meij, Hans; van der Meij, Jan; Harmsen, Ruth

    2015-01-01

    This study focuses on the design and testing of a motivational animated pedagogical agent (APA) in an inquiry learning environment on kinematics. The aim of including the APA was to enhance students’ perceptions of task relevance and self-efficacy. Given the under-representation of girls in science

  15. 2005 Annual Report of the American Psychological Association

    Science.gov (United States)

    American Psychologist, 2006

    2006-01-01

    This annual report of the American Psychological Association (APA) describes the association's activities and accomplishments in 2005. The examples provided in this report are a small sampling of all that APA is doing to advance the discipline of psychology in an ever-changing world.

  16. Ethics Education and Adjudication within Psychology.

    Science.gov (United States)

    Mills, David H.

    1984-01-01

    Provides an overview of the formal ethics system within psychology. Describes the structure of the American Psychological Association (APA) and state ethics systems, functions of APA's Committee on Scientific and Professional Ethics and Conduct, and its procedures for handling complaints. (Author/CMG)

  17. Aminopeptidase A is a functional target in angiogenic blood vessels

    NARCIS (Netherlands)

    Marchiò, Serena; Lahdenranta, Johanna; Schlingemann, Reinier O.; Valdembri, Donatella; Wesseling, Pieter; Arap, Marco A.; Hajitou, Amin; Ozawa, Michael G.; Trepel, Martin; Giordano, Ricardo J.; Nanus, David M.; Dijkman, Henri B. P. M.; Oosterwijk, Egbert; Sidman, Richard L.; Cooper, Max D.; Bussolino, Federico; Pasqualini, Renata; Arap, Wadih

    2004-01-01

    We show that a membrane-associated protease, aminopeptidase A (APA), is upregulated and enzymatically active in blood vessels of human tumors. To gain mechanistic insight, we evaluated angiogenesis in APA null mice. We found that, although these mice develop normally, they fail to mount the expected

  18. What Is Psychiatry?

    Medline Plus

    Full Text Available ... APA Foundation APA Annual Meeting Psychiatric News PsychiatryOnline Workplace Mental Health Sign In Join General Residents and ... panic disorder, PTSD, anxiety, obsessive-compulsive disorder, borderline personality disorder and eating disorders. Antipsychotic medications – used to ...

  19. Animated pedagogical agents effects on enhancing student motivation and learning in a science inquiry learning environment

    NARCIS (Netherlands)

    van der Meij, Hans; van der Meij, Jan; Harmsen, Ruth

    This study focuses on the design and testing of a motivational animated pedagogical agent (APA) in an inquiry learning environment on kinematics. The aim of including the APA was to enhance students’ perceptions of task relevance and selfefficacy. Given the under-representation of girls in science

  20. 78 FR 79619 - Patient Protection and Affordable Care Act; Program Integrity: Exchange, Premium Stabilization...

    Science.gov (United States)

    2013-12-31

    .... 155.705(a) by adding a cross reference to subpart M, so that the provision reads, ``Exchange functions... with section 553(b) and (c) of the Administrative Procedure Act (APA) (5 U.S.C. 553(b) & (c)). However... the finding and the reasons therefor in the notice. Section 553(d) of the APA ordinarily requires a 30...

  1. 76 FR 64017 - Approval and Promulgation of Air Quality Implementation Plans; South Carolina; Update to...

    Science.gov (United States)

    2011-10-17

    ... of Air Quality Implementation Plans; South Carolina; Update to Materials Incorporated by Reference... the ``good cause'' exemption in section 553(b)(3)(B) of the Administrative Procedure Act (APA) which... also finds that there is good cause under APA section 553(d)(3) for this correction to become effective...

  2. 76 FR 80226 - Technical Amendments

    Science.gov (United States)

    2011-12-23

    ... references to ``regional directors,'' and to replace those references with ``NCUA''. II. Regulatory Changes... final rule, effective upon publication. Generally, the Administrative Procedure Act (APA) requires a.... Additionally, the APA requires that a final rule must have a delayed effective date of 30 days from the date of...

  3. 78 FR 79283 - Community Reinvestment Act Regulations

    Science.gov (United States)

    2013-12-30

    ... by reference to asset-size criteria expressed in dollar amounts, and they further require the....C. 553(b)(B) of the Administrative Procedure Act (APA), an agency may, for good cause, find (and.... Under 5 U.S.C. 553(d)(3) of the APA, the required publication or service of a substantive rule shall be...

  4. 75 FR 55801 - Medicare Program; Prospective Payment System and Consolidated Billing for Skilled Nursing...

    Science.gov (United States)

    2010-09-14

    ... immediately preceding portion of the preamble text, which references the total PPS payment amounts displayed... the Administrative Procedure Act (APA) (5 U.S.C. 553(b)). We also ordinarily provide a 30-day delay in the effective date of the provisions of a notice in accordance with section 553(d) of the APA (5 U.S.C...

  5. 78 FR 77563 - Technical Amendments

    Science.gov (United States)

    2013-12-24

    ... now amending Sec. Sec. 700.2, 701.14, and 704.4,\\1\\ which still reference the former CRIS rating... Administrative Procedure Act (APA) requires a federal agency to provide the public with notice and the... unions. The APA permits an agency to forego the notice and comment period under certain circumstances...

  6. 77 FR 60629 - Administrative Simplification: Adoption of a Standard for a Unique Health Plan Identifier...

    Science.gov (United States)

    2012-10-04

    ... Procedure Act (APA) (5 U.S.C. 553(b)). However, we can waive these notice and comment procedures if the... the APA notice and comment procedures. This correcting document corrects technical and typographical..., first partial paragraph, line 1, the reference ``Table 14'' is corrected to read ``Table 10''. 3. On...

  7. 77 FR 32407 - Medicare Program; Changes to the Medicare Advantage and the Medicare Prescription Drug Benefit...

    Science.gov (United States)

    2012-06-01

    ....100 as being effective January 1, 2013. We also inadvertently omitted references to several sections... with section 553(b) of the Administrative Procedure Act (APA) (5 U.S.C. 553(b)). However, we can waive... the finding and the reasons therefore in the notice. Section 553(b) of the APA ordinarily requires a...

  8. 78 FR 52679 - Safety Standard for Cigarette Lighters; Adjusted Customs Value for Cigarette Lighters

    Science.gov (United States)

    2013-08-26

    ..., we also revised the reference to the Wholesale Price Index to refer instead to the Producer Price... Procedure Act Section 553(b)(3)(B) of the Administrative Procedure Act (APA) authorizes an agency to... received. Accordingly, the Commission finds that notice and comment is unnecessary. The APA also authorizes...

  9. 78 FR 37132 - Approval and Promulgation of Implementation Plans; Revised Format for Materials Being...

    Science.gov (United States)

    2013-06-20

    ... Promulgation of Implementation Plans; Revised Format for Materials Being Incorporated by Reference for Florida... the ``good cause'' exemption in section 553(b)(3)(B) of the Administrative Procedure Act (APA) which... recodification and miscellaneous revisions to the Florida SIP. EPA also finds that there is good cause under APA...

  10. 77 FR 59914 - Amended Notice: Request for Substantive Comments on the EAC's Proposed Requirements for Version 1...

    Science.gov (United States)

    2012-10-01

    ... Administrative Procedures Act (APA). It is a voluntary effort by the EAC to gather input from the public on the.... Furthermore, this request by the EAC for public comment is not intended to make any of the APA's rulemaking... independence and the development (with IEEE Working Group P1622 of a common data format for voting systems...

  11. 76 FR 30681 - Applications for New Awards; Technical Assistance and Dissemination To Improve Services and...

    Science.gov (United States)

    2011-05-26

    ... the TACC Web site: http://www.tadnet.org/home?format=html . (g) Contribute, on an ongoing basis... Procedure Act (APA) (5 U.S.C. 553) the Department generally offers interested parties the opportunity to... requirements of the APA inapplicable to the priority in this notice. Program Authority: 20 U.S.C. 1463 and 1481...

  12. 78 FR 48048 - Student Assistance General Provisions

    Science.gov (United States)

    2013-08-07

    ... electronically in an Adobe Portable Document Format (PDF) directly to OHA through standard Web-based screens and..., and Delayed Effective Date Under the Administrative Procedure Act (5 U.S.C. 553) (APA), the Department.... The revised regulations are therefore rules of agency practice and procedure, and the APA does not...

  13. 76 FR 16741 - Applications for New Awards; Erma Byrd Scholarship Program

    Science.gov (United States)

    2011-03-25

    ... (APA) (5 U.S.C. 553) and section 437 of the General Education Provisions Act (GEPA), 20 U.S.C. 1232(d..., 2010, Public Law 111-117 provides, however, that the provisions of section 553 of the APA and section... with disabilities can obtain a copy of the application package in an accessible format (e.g. braille...

  14. 78 FR 57066 - Final Waivers and Extensions of Project Periods; American Indian Vocational Rehabilitation...

    Science.gov (United States)

    2013-09-17

    ... ending September 30, 2014. Waiver of Delayed Effective Date The Administrative Procedure Act (APA... the APA's delayed effective date provision for good cause. Regulatory Flexibility Act Certification... regulations in 34 CFR Part 79. Accessible Format: Individuals with disabilities can obtain this document in an...

  15. Afghanistans Oil, Gas, and Minerals Industries: $488 Million in U.S. Efforts Show Limited Progress Overall, and Challenges Prevent Further Investment and Growth

    Science.gov (United States)

    2016-01-01

    26 SIGAR 16-11-AR/Afghanistan’s Extractive Industries Page vi ABBREVIATIONS AGS Afghanistan Geological Survey APA ...home to a variety of geological formations with an abundance of minerals, precious metals, gemstones, and hydrocarbons, estimated by TFBSO to be worth...mineral resources. The MoMP’s Afghan Petroleum Authority ( APA ) has exclusive responsibility for establishing hydrocarbon policy and regulating the

  16. 76 FR 25311 - Applications for New Awards; Technology and Media Services for Individuals With Disabilities...

    Science.gov (United States)

    2011-05-04

    ... distribution in alternate formats, such as video streaming. Provide closed captioned and described master... . Waiver of Proposed Rulemaking: Under the Administrative Procedure Act (APA) (5 U.S.C. 553) the Department.... Section 681(d) of IDEA, however, makes the public comment requirements of the APA inapplicable to the...

  17. 78 FR 79319 - Amendment to Standards and Practices for All Appropriate Inquiries Under CERCLA

    Science.gov (United States)

    2013-12-30

    ... Standard? The ASTM E1527-13 standard is similar to the ASTM E1527-05 standard in format, process, and areas... under Section 553 of the Administrative Procedure Act (APA) for this revision to become effective immediately. Section 553(d)(3) of the APA allows an effective date less than 30 days after publication ``as...

  18. 76 FR 14812 - Final Regulation Extending the Reporting Deadline for Year 2010 Data Elements Required Under the...

    Science.gov (United States)

    2011-03-18

    ... Abbreviations. The following acronyms and abbreviations are used in this document. APA Administrative Procedure... (XML) format. Development of the reporting tool has involved translating the detailed industry-specific... cause exemption under the Administrative Procedure Act (APA) to take the actions set forth in this final...

  19. 77 FR 1023 - Regulated Navigation Area; Arthur Kill, NY and NJ

    Science.gov (United States)

    2012-01-09

    ... an unbound format, no larger than 8\\1/2\\ by 11 inches, suitable for copying and electronic filing. If... not now plan to hold a public meeting within the meaning of the Administrative Procedure Act (APA), 5... prior notice and opportunity to comment, under the authority of the Administrative Procedure Act (APA...

  20. 75 FR 8316 - Office of Postsecondary Education; Overview Information; Erma Byrd Scholarship Program; Notice...

    Science.gov (United States)

    2010-02-24

    ... (APA) (5 U.S.C. 553) and section 437 of the General Education Provisions Act (GEPA), 20 U.S.C. 1232(d..., Public Law 111-117 provides, however, that the provisions of section 553 of the APA and section 437 of... an accessible format (e.g., braille, large print, audiotape, or computer diskette) by contacting the...

  1. Design and Validation of a Rubric to Assess the Use of American Psychological Association Style in Scientific Articles

    Science.gov (United States)

    Merma Molina, Gladys; Peña Alfaro, Hilda; Peña Alfaro González, Silvia Rosa

    2017-01-01

    In this study, the researchers will explore the process of designing and validating a rubric to evaluate the adaptation of scientific articles in the format of the "American Psychological Association" (APA). The rubric will evaluate certain aspects of the APA format that allow authors, editors, and evaluators to decide if the scientific…

  2. 77 FR 40805 - Federal Pell Grant Program; Correction

    Science.gov (United States)

    2012-07-11

    ... Date with the following two paragraphs: The Administrative Procedure Act (APA) generally requires that... reduced amounts of Pell Grant funds, there is good cause to waive the delayed effective dates in the APA and the CRA and make this interim final rule effective on the day it is published. Accessible Format...

  3. 77 FR 54905 - Request for Substantive Comments on the EAC's Proposed Requirements for Version 1.1 of the...

    Science.gov (United States)

    2012-09-06

    ... (with IEEE Working Group P1622 of a common data format for voting systems. Changes to VVSG 1.1 Since the... Administrative Procedures Act (APA). It is a voluntary effort by the EAC to gather input from the public on the.... Furthermore, this request by the EAC for public comment is not intended to make any of the APA's rulemaking...

  4. Introduction To The Special Section: The American Psychiatric Association's Research Agenda For The DSM-V

    DEFF Research Database (Denmark)

    Widiger, Thomas A; Simonsen, Erik

    2005-01-01

    of the American Psychiatric Association's (APA) Diagnostic and Statistical Manual of Mental Disorders. This article provides the historical background for and a brief description of the first conference, which was concerned with the research that would help move the field toward a dimensional classification...... of personality disorder. (PsycINFO Database Record (c) 2008 APA, all rights reserved) (from the journal abstract)...

  5. Study to the presence of antipolymer antibodies in a group of Dutch women with a silicone breast implant. Part II

    NARCIS (Netherlands)

    Jong WH de; Kallewaard M; Verhoef CM; Bijlsma JWJ; Schouten JSAG; Loveren H van; Afdeling Reumatologie en; LPI; LGM

    2002-01-01

    The presence of antipolymer antibodies (APA) was reported in women with severe symptoms and a silicone breast implant (SBI). The aim of the present study was to determine whether there exists a population of symptomatic SBI recipients with a high prevalence of APA in the Netherlands. Participants

  6. Aminopeptidase A is a functional target in angiogenic blood vessels.

    NARCIS (Netherlands)

    Marchio, S.; Lahdenranta, J.; Schlingemann, R.O.; Valdembri, D.; Wesseling, P.; Arap, M.A.; Hajitou, A.; Ozawa, M.G.; Trepel, M.; Giordano, R.J.; Nanus, D.M.; Dijkman, H.B.P.M.; Oosterwijk, E.; Sidman, R.L.; Cooper, M.D.; Bussolino, F.; Pasqualini, R.; Arap, W.

    2004-01-01

    We show that a membrane-associated protease, aminopeptidase A (APA), is upregulated and enzymatically active in blood vessels of human tumors. To gain mechanistic insight, we evaluated angiogenesis in APA null mice. We found that, although these mice develop normally, they fail to mount the expected

  7. Airborne Tactical Crossload Planner

    Science.gov (United States)

    2017-12-01

    Regiment AGL above ground level AO area of operation APA American psychological association ASOP airborne standard operating procedure A/C aircraft...awarded a research contract to develop a tactical crossload tool. [C]omputer assisted Airborne Planning Application ( APA ) that provides a

  8. 49 CFR 171.7 - Reference material.

    Science.gov (United States)

    2010-10-01

    .../publications.com; AAR Manual of Standards and Recommended Practices, Section C—Part III, Specifications for... Edition, March 1996 172.102. American Pyrotechnics Association (APA), P.O. Box 30438, Bethesda, MD 20824, (301) 907-8181, www.americanpyro.com: APA Standard 87-1, Standard for Construction and Approval for...

  9. Probability as certainty : Dichotomous thinking and the misuse of p values

    NARCIS (Netherlands)

    Hoekstra, Rink; Finch, Sue; Kiers, Henk A.L.; Johnson, Addie

    2006-01-01

    Significance testing is widely used and often criticized. The Task Force on Statistical Inference of the American Psychological Association (TFSI, APA; Wilkinson & TFSI, 1999) addressed the use of significance testing and made recommendations that were incorporated in the fifth edition of the APA

  10. An Introduction to Confidence Intervals for Both Statistical Estimates and Effect Sizes.

    Science.gov (United States)

    Capraro, Mary Margaret

    This paper summarizes methods of estimating confidence intervals, including classical intervals and intervals for effect sizes. The recent American Psychological Association (APA) Task Force on Statistical Inference report suggested that confidence intervals should always be reported, and the fifth edition of the APA "Publication Manual"…

  11. Statistical Methods in Psychology Journals.

    Science.gov (United States)

    Willkinson, Leland

    1999-01-01

    Proposes guidelines for revising the American Psychological Association (APA) publication manual or other APA materials to clarify the application of statistics in research reports. The guidelines are intended to induce authors and editors to recognize the thoughtless application of statistical methods. Contains 54 references. (SLD)

  12. 76 FR 55788 - Amendments To Include New Applicant Types on Form ID

    Science.gov (United States)

    2011-09-09

    ... of non-agency parties). The APA also generally requires publication of a rule in the Federal Register...\\ See EDGAR Filing Manual (Volume I) General Information (Section 2.4, Accessing EDGAR). Currently, Form... Administrative Procedure Act (``APA'') \\34\\ generally requires an agency to publish, before adopting a rule...

  13. Interpreting and Reporting Effect Sizes in Research Investigations.

    Science.gov (United States)

    Tapia, Martha; Marsh, George E., II

    Since 1994, the American Psychological Association (APA) has advocated the inclusion of effect size indices in reporting research to elucidate the statistical significance of studies based on sample size. In 2001, the fifth edition of the APA "Publication Manual" stressed the importance of including an index of effect size to clarify…

  14. Yeki Bood/Yeki Na Bood: Writing and Publishing as a Teacher Researcher.

    Science.gov (United States)

    Fecho, Bob

    2003-01-01

    Discusses considerations faced by practitioner researchers as they write for publication, particularly as they encounter the template of the Publication Manual of the American Psychological Association (APA). Argues that some APA conventions--such as beginning an article with theory rather than the story of the research--do not suite the purposes…

  15. An Introductory Summary of Various Effect Size Choices.

    Science.gov (United States)

    Cromwell, Susan

    This paper provides a tutorial summary of some of the many effect size choices so that members of the Southwest Educational Research Association would be better able to follow the recommendations of the American Psychological Association (APA) publication manual, the APA Task Force on Statistical Inference, and the publication requirements of some…

  16. Dampak Dan Pendekatan Pembangunan Madura Pasca Jembatan Suramadu

    OpenAIRE

    Idri Shaffat, Idri Shaffat

    2012-01-01

    Abstrac Kehadiran Jumbatan Suramadu di samping mempercepat transportasi dari Surabaya ke Madura atau sebaliknya, juga diharapkan dapat memberikan dampak positif khususnya bagi peningkatan taraf hidup masyarakat Madura. Tulisan ini mencoba untuk menjelaskan dampak positif adanya Jembatan Suramadu dengan tiga kemungkinan, yaitu : [1] keberadaan Jembatan Suramadu tidak memberikan dampak apa-apa selain terjadinya Perubahan alat dan tempat transportasi, [2] dengan keberadaan Jembatan Suramadu, mas...

  17. Courseware Development with Animated Pedagogical Agents in Learning System to Improve Learning Motivation

    Science.gov (United States)

    Chin, Kai-Yi; Hong, Zeng-Wei; Huang, Yueh-Min; Shen, Wei-Wei; Lin, Jim-Min

    2016-01-01

    The addition of animated pedagogical agents (APAs) in computer-assisted learning (CAL) systems could successfully enhance students' learning motivation and engagement in learning activities. Conventionally, the APA incorporated multimedia materials are constructed through the cooperation of teachers and software programmers. However, the thinking…

  18. 75 FR 32858 - Medicare Program; Policy and Technical Changes to the Medicare Advantage and the Medicare...

    Science.gov (United States)

    2010-06-10

    ... changes to Sec. 423.551 regarding changes in ownership during a PDP term of contract. In presenting these... Administrative Procedure Act (APA) (5 U.S.C. 553(b)). In addition, section 553(d) of the APA (5 U.S.C. 553(b... effective date if the Secretary finds, for good cause, that the notice and comment process is impracticable...

  19. 77 FR 69761 - Regulated Navigation Area; Recovery Operations, the Port of New York and New Jersey, NJ and NY

    Science.gov (United States)

    2012-11-21

    ... INFORMATION: Table of Acronyms APA Administrative Procedure Act DHS Department of Homeland Security FR Federal.... If you submit your comments by mail or hand delivery, submit them in an unbound format, no larger... Administrative Procedure Act (APA) (5 U.S.C. 553). Section 553(b) provides that a general notice of proposed...

  20. Internship Training Directors' Perceptions of School Psychology Internship Applicants

    Science.gov (United States)

    Mahoney, Emery B.; Perfect, Michelle M.; Edwinson, Roxanne M.

    2015-01-01

    Since the mid-1990s, an imbalance between the number of available American Psychological Association (APA)-accredited internships and applicants has existed. In 2014, 14% of predoctoral psychology students who applied for internships accredited by the APA or members of the Association of Psychology Postdoctoral and Internship Centers (APPIC) did…

  1. Teen Dating Violence Prevention Program Assessment

    Science.gov (United States)

    Lucas, Quincy Arrianna Rose

    2013-01-01

    The American Psychological Association (APA) has identified the prevention of and intervention in relationship violence as a top priority (APA, n.d.). According to the Center for Disease Control and Prevention's 2012 Teen Dating Violence Fact Sheet, dating violence is a serious problem in the United States. In accordance with Foshee et al. (1998):…

  2. Amplexicaule A exerts anti-tumor effects by inducing apoptosis in human breast cancer

    Science.gov (United States)

    Shu, Guangwen; Wan, Dingrong; He, Feng; Loaec, Morgann; Ding, Yali; Li, Jun; Dovat, Sinisa; Yang, Gaungzhong; Song, Chunhua

    2016-01-01

    Chemotherapy is the main treatment for patients with breast cancer metastases, but natural alternatives have been receiving attention for their potential as novel anti-tumor reagents. Amplexicaule A (APA) is a flavonoid glucoside isolated from rhizomes of Polygonum amplexicaule D. Don var. sinense Forb (PADF). We found that APA has anti-tumor effects in a breast cancer xenograft mouse model and induces apoptosis in breast cancer cell lines. APA increased levels of cleaved caspase-3,-8,-9 and PARP, which resulted from suppression of MCL-1 and BCL-2 expression in the cells. APA also inactivated the Akt/mTOR pathway in breast cancer cells. Thus, APA exerts a strong anti-tumor effect on breast cancer cells, most likely through induction of apoptosis. Our study is the first to identify this novel anti-tumor compound and provides a new strategy for isolation and separation of single compounds from herbs. PMID:26943775

  3. The use of ethnic minority populations in published psychological research, 1990-1999.

    Science.gov (United States)

    Imada, Toshie; Schiavo, R Steven

    2005-09-01

    For this study, the authors analyzed the contents of 16 psychology journals for the presence of empirical articles on African Americans, Latinos, Asians, and Native Americans during the period ranging from 1990 to 1999. In 6 APA journals, there was a low percentage (4.7%) of such articles. African Americans were the most studied ethnic group. Data collected for this study also indicated that minority research has been increasing more in non-APA journals than in APA journals. In both APA and non-APA journals, counseling-oriented journals had higher percentages of minority articles than did journals of other subdisciplines. Possible explanations, consequences, and suggestions for future research are discussed.

  4. Alternative polyadenylation of tumor suppressor genes in small intestinal neuroendocrine tumors

    DEFF Research Database (Denmark)

    Rehfeld, Anders Aagaard; Plass, Mireya; Døssing, Kristina

    2014-01-01

    The tumorigenesis of small intestinal neuroendocrine tumors (SI-NETs) is poorly understood. Recent studies have associated alternative polyadenylation (APA) with proliferation, cell transformation, and cancer. Polyadenylation is the process in which the pre-messenger RNA is cleaved at a polyA site...... and a polyA tail is added. Genes with two or more polyA sites can undergo APA. This produces two or more distinct mRNA isoforms with different 3' untranslated regions. Additionally, APA can also produce mRNAs containing different 3'-terminal coding regions. Therefore, APA alters both the repertoire...... and the expression level of proteins. Here, we used high-throughput sequencing data to map polyA sites and characterize polyadenylation genome-wide in three SI-NETs and a reference sample. In the tumors, 16 genes showed significant changes of APA pattern, which lead to either the 3' truncation of mRNA coding regions...

  5. The Southern Society for Philosophy and Psychology and Francis Cecil Sumner.

    Science.gov (United States)

    Thomas, Roger K

    2011-01-01

    In 1939, a psychologist could become a member of the Southern Society for Philosophy and Psychology (SSPP) automatically with the endorsement of two members, payment of dues, and membership in the American Psychological Association (APA). Non-APA members with endorsements and payment of dues had to be voted in by the membership. In 1940, the rules for admission were changed to eliminate the automatic membership for APA members. Francis Cecil Sumner, the first African American PhD in psychology, qualified for SSPP membership as a member of the APA in 1939, but the SSPP's council delayed his membership and introduced the amendment to its constitution that eliminated Sumner's route to membership. This article examines the circumstances surrounding council's actions and the role that Sumner's application for membership played in it as an example of the role that race and discrimination played in the decision to change the route to SSPP membership for members of the APA.

  6. Auricular point acupressure as an adjunct analgesic treatment for cancer patients: a feasibility study.

    Science.gov (United States)

    Yeh, Chao Hsing; Chien, Lung-Chang; Chiang, Yi Chien; Ren, Dianxu; Suen, Lorna Kwai-Ping

    2015-06-01

    This study aimed (1) to examine the feasibility of an auricular point acupressure (APA) research protocol in terms of recruitment and for the assessment and management of pain and (2) to examine the potential APA analgesic effects for cancer patients. This study was a repeated-measures one-group design. Participants were recruited from the cancer center follow-up clinic affiliated with a large university hospital in the northeastern United States. Participants included 50 patients aged 55-87 years with a diagnosis of cancer. Participants received 7 days of APA treatment for their pain. After appropriate acupoints were identified, vaccaria seeds were carefully taped onto each selected auricular point on each ear. The study recruitment and retention rates were 92% and 91%, respectively. Importantly, the study found preliminary evidence for the analgesic effects of APA for cancer pain management. For example, by the end of the 7-day study, APA reduced pain intensity more than 55% for "worst pain" and about 57% for "average pain" and "pain intensity." Moreover, the use of pain medication was reduced during the APA treatment (e.g., 78% of patients [n = 39] took less pain medication than before the treatment). APA appears to be highly acceptable to patients with cancer-related pain. However, without a placebo control, we cannot draw conclusive evidence for the analgesic effect of APA for cancer patients. A sham group must be added to future studies to differentiate the true effects of APA from the possible psychological effects of the APA treatment. Copyright © 2015 American Society for Pain Management Nursing. Published by Elsevier Inc. All rights reserved.

  7. Alkaline Phosphatase Activity : an overlooked player on the phosphate behavior in macrotidal estuaries

    Science.gov (United States)

    Delmas, Daniel; Labry, Claire; Youenou, Agnes; Quere, Julien; Auguet, Jean Christophe; Montanie, Helene

    2014-05-01

    The non-conservative behavior of phosphate within the estuarine salinity gradient is essentially assigned to physico-chemical processes, such as desorption at low salinity and to benthic exchanges. Microbial phosphatase activity (APA), generally related to phosphate deficiency, is seldom studied in phosphate rich estuarine waters. In order to address the impact of microbial activity (bacterial abundance, production BSP, APA) on phosphate behavior, we studied these activities on a seasonal basis within the salinity gradient of two macrotidal estuaries presenting different levels of suspended solids. Whatever the season the Charente estuary is characterized by high levels of Suspended Particulate Matter (SPM > 1g.L-1), particularly in the Maximum Turbidity Zone (MTZ) located at the 5-10 psu. In this area characterized by high BSP and APA there is a significant increase of PO4 levels especially during summer. In the Aulne estuary the particle load is significantly lower (1/10) but high BSP and APA are equally recorded. In the highly turbid waters of the Charente estuary, active phytoplankton is virtually absent as pheopigments constitute up to 80% of the total pigments, particularly in the MTZ, therefore APA may essentially have a bacterial origin. In the Aulne estuary attached bacteria are dominant, both in numbers and production, and their distribution along the haline gradient perfectly follows those of APA and phosphate levels. These observations, associated with the very close relationships observed between APA, SPM and BSP, suggest that APA derive mainly from bacterial (attached) origin and operate at the expense of particulate phosphorus and hence contribute to PO4 regeneration, especially in spring and summer. Finally, as APA increased as PO4, whereas the reverse is observed in both fresh and marine waters, an original scheme for APA regulation, related to the large dominance of attached bacteria can be described for the estuarine waters.

  8. Effect of KCNJ5 Mutations on Gene Expression in Aldosterone-Producing Adenomas and Adrenocortical Cells

    Science.gov (United States)

    Monticone, Silvia; Hattangady, Namita G.; Nishimoto, Koshiro; Mantero, Franco; Rubin, Beatrice; Cicala, Maria Verena; Pezzani, Raffaele; Auchus, Richard J.; Ghayee, Hans K.; Shibata, Hirotaka; Kurihara, Isao; Williams, Tracy A.; Giri, Judith G.; Bollag, Roni J.; Edwards, Michael A.; Isales, Carlos M.

    2012-01-01

    Context: Primary aldosteronism is a heterogeneous disease that includes both sporadic and familial forms. A point mutation in the KCNJ5 gene is responsible for familial hyperaldosteronism type III. Somatic mutations in KCNJ5 also occur in sporadic aldosterone producing adenomas (APA). Objective: The objective of the study was to define the effect of the KCNJ5 mutations on gene expression and aldosterone production using APA tissue and human adrenocortical cells. Methods: A microarray analysis was used to compare the transcriptome profiles of female-derived APA samples with and without KCNJ5 mutations and HAC15 adrenal cells overexpressing either mutated or wild-type KCNJ5. Real-time PCR validated a set of differentially expressed genes. Immunohistochemical staining localized the KCNJ5 expression in normal adrenals and APA. Results: We report a 38% (18 of 47) prevalence of KCNJ5 mutations in APA. KCNJ5 immunostaining was highest in the zona glomerulosa of NA and heterogeneous in APA tissue, and KCNJ5 mRNA was 4-fold higher in APA compared with normal adrenals (P APA with and without KCNJ5 mutations displayed slightly different gene expression patterns, notably the aldosterone synthase gene (CYP11B2) was more highly expressed in APA with KCNJ5 mutations. Overexpression of KCNJ5 mutations in HAC15 increased aldosterone production and altered expression of 36 genes by greater than 2.5-fold (P APA, and our data suggest that these mutations increase expression of CYP11B2 and NR4A2, thus increasing aldosterone production. PMID:22628608

  9. Excess of Aminopeptidase A in the Brain Elevates Blood Pressure via the Angiotensin II Type 1 and Bradykinin B2 Receptors without Dipsogenic Effect

    Directory of Open Access Journals (Sweden)

    Takuto Nakamura

    2017-01-01

    Full Text Available Aminopeptidase A (APA cleaves angiotensin (Ang II, kallidin, and other related peptides. In the brain, it activates the renin angiotensin system and causes hypertension. Limited data are available on the dipsogenic effect of APA and pressor effect of degraded peptides of APA such as bradykinin. Wistar-Kyoto rats received intracerebroventricular (icv APA in a conscious, unrestrained state after pretreatment with (i vehicle, (ii 80 μg of telmisartan, an Ang II type-1 (AT1 receptor blocker, (iii 800 nmol of amastatin, an aminopeptidase inhibitor, and (iv 1 nmol of HOE-140, a bradykinin B2 receptor blocker. Icv administration of 400 and 800 ng of APA increased blood pressure by 12.6 ± 3.0 and 19.0 ± 3.1 mmHg, respectively. APA did not evoke drinking behavior. Pressor response to APA was attenuated on pretreatment with telmisartan (vehicle: 22.1 ± 2.2 mmHg versus telmisartan: 10.4 ± 3.2 mmHg. Pressor response to APA was also attenuated with amastatin and HOE-140 (vehicle: 26.5 ± 1.1 mmHg, amastatin: 14.4 ± 4.2 mmHg, HOE-140: 16.4 ± 2.2 mmHg. In conclusion, APA increase in the brain evokes a pressor response via enzymatic activity without dipsogenic effect. AT1 receptors and B2 receptors in the brain may contribute to the APA-induced pressor response.

  10. Immunohistochemical characteristics of atypical polypoid adenomyoma with special reference to h-caldesmon.

    Science.gov (United States)

    Horita, Ayako; Kurata, Atsushi; Maeda, Daichi; Fukayama, Masashi; Sakamoto, Atsuhiko

    2011-01-01

    Atypical polypoid adenomyoma (APA) is a relatively rare benign uterine tumor, histologically characterized by proliferation of irregular endometrioid glands accompanied by stromal cells of smooth muscle origin. As the epithelial components of APA usually show cytological atypia, a differential diagnosis between this tumor and endometrioid carcinoma invading myometrium is often difficult, especially in curettage material. This distinction is clinically very important to avoid unnecessary hysterectomy. However, only a few immunohistochemical studies of APA that differentiate it from malignancy have been published. Therefore, we have investigated the expression of several antigens in APA and compared them with those present in myoinvasive carcinoma. Six specimens of APA were studied, along with controls of endometrioid carcinoma invading myometrium. Antibodies to p53, Ki-67, CD10, and h-caldesmon reacted positively using immunohistochemistry. Variable positive expressions of p53 and Ki-67 were observed in both epithelial and stromal components of APA, and in myoinvasive endometrioid carcinoma. CD10 was negative or partially and weakly positive whereas h-caldesmon was completely negative in the stromal cells of all 6 specimens of APA. However, in the myometrium in which endometrioid carcinoma invaded, a fringe-like positive staining pattern was occasionally observed for CD10, whereas a diffuse positive signal was obtained for h-caldesmon. The results of this study indicate that immunohistochemically, p53, and Ki-67 are not reliable markers but that h-caldesmon is useful in distinguishing APA from myoinvasive endometrioid carcinoma. Further, our data suggest that the stromal cells of APA are mainly immature smooth muscle cells, and thus APA may be a mixed tumor.

  11. Increasing phytoplankton-available phosphorus and inhibition of macrophyte on phytoplankton bloom.

    Science.gov (United States)

    Dai, Yanran; Wu, Juan; Ma, Xiaohang; Zhong, Fei; Cui, Naxin; Cheng, Shuiping

    2017-02-01

    We assembled mesocosms to address the coherent mechanisms that an increasing phosphorus (P) concentration in water columns coupled with the phytoplankton bloom and identify the performance gap of regulating phytoplankton growth between two macrophyte species, Ceratophyllum demersum L. and Vallisneria spiralis L. Intense alkaline phosphatase activities (APA) were observed in the unplanted control, with their predominant part, phytoplankton APA (accounting for up to 44.7% of the total APA), and another large share, bacterial APA. These correspond with the large average concentration of total phosphorus (TP), total dissolved phosphorus (TDP) and soluble reactive (SRP) as well as high phytoplankton density in the water column. The consistency among P concentrations, phytoplankton density and APA, together with the positive impact of phytoplankton density on total APA revealed by the structural equation modelling (SEM), indicates that facilitated APA levels in water is an essential strategy for phytoplankton to enhance the available P. Furthermore, a positive interaction between phytoplankton APA and bacteria APA was detected, suggesting a potential collaboration between phytoplankton and bacteria to boost available P content in the water column. Both macrophyte species had a prominent performance on regulating phytoplankton proliferation. The phytoplankton density and quantum yield in C. demersum systems were all significantly lower (33.8% and 24.0%) than those in V. spiralis systems. Additionally, a greater decoupling effect of C. demersum on the relationship between P, APA, phytoplankton density, bacteria dynamic and quantum yield was revealed by SEM. These results imply that the preferred tactic of different species could lead to the performance gap. Copyright © 2016 Elsevier B.V. All rights reserved.

  12. Pelvic magnetic resonance imaging angioanatomy of the arterial blood supply to the penis in suspected prostate cancer patients

    International Nuclear Information System (INIS)

    Thai, Cao Tan; Karam, Ibrahim Michel; Nguyen-Thi, Phi Linh; Lefèvre, Frédéric; Hubert, Jacques; Felblinger, Jacques; Eschwège, Pascal

    2015-01-01

    Highlights: • Three patterns of penile arterial supply (according to the classification of Stéphane Droupy). • Our classification about accessory pudendal artery. • Origin of accessory pudendal artery. - Abstract: Purpose: To describe the internal pudendal artery (IPA) and accessory pudendal artery (APA) detected by magnetic resonance (MR) angiography to help surgeons to find and preserve them during radical prostatectomy (RP). Materials and methods: Constrast-enhanced MR 3.0 T angiography of the pelvis were performed in 111 male patients suspected diagnosis of prostate cancer (PCa), and describe the penile arterial blood supply. Results: There are three patterns of the arterial blood supply to the penis (IPA and/or APA) accounting for 51.4%, 46.8% and 1.8% of cases, respectively. About the accessory pudendal artery (APA): 54/111 (48.6%) patients had APA with five different branching patterns, they were type I (APA bilateral symmetry): 17 (31.5%); type II (APA bilateral asymmetry): 1 (1.9%); type III (APA unilateral lateral): 13 (24%); type IV (APA unilateral apical): 21 (38.9%); type V (APA unilateral mix): 2 (3.7%). APA origin were from inferior epigastric artery (IEA): 7 (9.5%); from inferior vesical artery (IVA): 32 (43.2%); from obturator artery (OA): 35 (47.3%). Conclusion: A precise angioanatomic evalutation of arteries destined to the penis by MR angiography pre-operation for male pelvic organs will help surgeons to preserve them and contributes to reduce the erectile dysfunction after these procedures

  13. Pelvic magnetic resonance imaging angioanatomy of the arterial blood supply to the penis in suspected prostate cancer patients

    Energy Technology Data Exchange (ETDEWEB)

    Thai, Cao Tan, E-mail: bstanhatinh@gmail.com [Department of Urology, Brabois Hospital, University Hospital of Nancy, Rue du Morvan, 54500 Vandoeuvre Lès Nancy Cedex (France); IADI Laboratory, INSERM-U947, Brabois Hospital, University Hospital of Nancy, Tour Drouet, rue du Morvan, 54511 Vandoeuvre Lès Nancy Cedex (France); Karam, Ibrahim Michel [Clinical Epidemiology and Evaluation Department, University Hospital of Nancy (France); Department of Anatomy, Faculty of Medicine Nancy, 9 Avenue de la Foret de haye BP, 54505 Vandoeuvre Lès Nancy Cedex (France); Nguyen-Thi, Phi Linh [Clinical Epidemiology and Evaluation Department, University Hospital of Nancy (France); INSERM, CIC-EC CIE6, 92 Avenue du Maréchal de Lattre de Tassigny, 54000 Nancy (France); Lefèvre, Frédéric [Department of Radiology, Brabois Hospital, University Hospital of Nancy, Rue du Morvan, 54500 Vandoeuvre Lès Nancy Cedex (France); Hubert, Jacques [Department of Urology, Brabois Hospital, University Hospital of Nancy, Rue du Morvan, 54500 Vandoeuvre Lès Nancy Cedex (France); IADI Laboratory, INSERM-U947, Brabois Hospital, University Hospital of Nancy, Tour Drouet, rue du Morvan, 54511 Vandoeuvre Lès Nancy Cedex (France); Felblinger, Jacques [IADI Laboratory, INSERM-U947, Brabois Hospital, University Hospital of Nancy, Tour Drouet, rue du Morvan, 54511 Vandoeuvre Lès Nancy Cedex (France); Eschwège, Pascal [Department of Urology, Brabois Hospital, University Hospital of Nancy, Rue du Morvan, 54500 Vandoeuvre Lès Nancy Cedex (France)

    2015-05-15

    Highlights: • Three patterns of penile arterial supply (according to the classification of Stéphane Droupy). • Our classification about accessory pudendal artery. • Origin of accessory pudendal artery. - Abstract: Purpose: To describe the internal pudendal artery (IPA) and accessory pudendal artery (APA) detected by magnetic resonance (MR) angiography to help surgeons to find and preserve them during radical prostatectomy (RP). Materials and methods: Constrast-enhanced MR 3.0 T angiography of the pelvis were performed in 111 male patients suspected diagnosis of prostate cancer (PCa), and describe the penile arterial blood supply. Results: There are three patterns of the arterial blood supply to the penis (IPA and/or APA) accounting for 51.4%, 46.8% and 1.8% of cases, respectively. About the accessory pudendal artery (APA): 54/111 (48.6%) patients had APA with five different branching patterns, they were type I (APA bilateral symmetry): 17 (31.5%); type II (APA bilateral asymmetry): 1 (1.9%); type III (APA unilateral lateral): 13 (24%); type IV (APA unilateral apical): 21 (38.9%); type V (APA unilateral mix): 2 (3.7%). APA origin were from inferior epigastric artery (IEA): 7 (9.5%); from inferior vesical artery (IVA): 32 (43.2%); from obturator artery (OA): 35 (47.3%). Conclusion: A precise angioanatomic evalutation of arteries destined to the penis by MR angiography pre-operation for male pelvic organs will help surgeons to preserve them and contributes to reduce the erectile dysfunction after these procedures.

  14. DHEA, DHEAS and PCOS.

    Science.gov (United States)

    Goodarzi, Mark O; Carmina, Enrico; Azziz, Ricardo

    2015-01-01

    Approximately 20-30% of PCOS women demonstrate excess adrenal precursor androgen (APA) production, primarily using DHEAS as a marker of APA in general and more specifically DHEA, synthesis. The role of APA excess in determining or causing PCOS is unclear, although observations in patients with inherited APA excess (e.g., patients with 21-hydroxylase deficient congenital classic or non-classic adrenal hyperplasia) demonstrate that APA excess can result in a PCOS-like phenotype. Inherited defects of the enzymes responsible for steroid biosynthesis, or defects in cortisol metabolism, account for only a very small fraction of women suffering from hyperandrogenism or APA excess. Rather, women with PCOS and APA excess appear to have a generalized exaggeration in adrenal steroidogenesis in response to ACTH stimulation, although they do not have an overt hypothalamic-pituitary-adrenal axis dysfunction. In general, extra-adrenal factors, including obesity, insulin and glucose levels, and ovarian secretions, play a limited role in the increased APA production observed in PCOS. Substantial heritabilities of APAs, particularly DHEAS, have been found in the general population and in women with PCOS; however, the handful of SNPs discovered to date account only for a small portion of the inheritance of these traits. Paradoxically, and as in men, elevated levels of DHEAS appear to be protective against cardiovascular risk in women, although the role of DHEAS in modulating this risk in women with PCOS remains unknown. In summary, the exact cause of APA excess in PCOS remains unclear, although it may reflect a generalized and inherited exaggeration in androgen biosynthesis of an inherited nature. Copyright © 2014 Elsevier Ltd. All rights reserved.

  15. Characterization of pituitary cells targeted by antipituitary antibodies in patients with isolated autoimmune diseases without pituitary insufficiency may help to foresee the kind of future hypopituitarism.

    Science.gov (United States)

    De Bellis, A; Dello Iacovo, A; Bellastella, G; Savoia, A; Cozzolino, D; Sinisi, A A; Bizzarro, A; Bellastella, A; Giugliano, D

    2014-10-01

    Detection of antipituitary antibodies (APA) at high levels and with a particular immunofluorescence pattern in patients with autoimmune polyendocrine syndromes may indicate a possible future autoimmune pituitary involvement. This longitudinal study was aimed at characterizing in patients with a single organ-specific autoimmune disease the pituitary cells targeted by APA at start, verifying whether this characterization allows to foresee the kind of possible subsequent hypopituitarism. Thirty-six APA positive and 40 APA negative patients with isolated autoimmune diseases participated in the study. None of them had pituitary dysfunction at entry. Characterization by four-layer immunofluorescence of pituitary cells targeted by APA in APA positive patients at entry and study of pituitary function in all patients were performed every 6 months during a 5 year follow-up. Antipituitary antibodies immunostained selectively one type of pituitary-secreting cells in 21 patients (58.3 %, group 1), and several types of pituitary cells in the remaining 15 (41.7 %, group 2). All patients in group 1 showed subsequently a pituitary insufficiency, corresponding to the type of cells targeted by APA in 18 of them (85.7 %). Only 8 out of 15 patients in group 2 (53.3 %) showed a hypopituitarism, isolated in 7 and combined in the other one. None of APA negative patients showed hypopituitarism. The characterization of pituitary cells targeted by APA in patients with isolated autoimmune diseases, when the pituitary function is still normal, may help to foresee the kind of subsequent hypopituitarism, especially when APA immunostained selectively only one type of pituitary cells. A careful follow-up of pituitary function in these patients is advisable to allow an early diagnosis of hypopituitarism, even in subclinical phase and a consequent timely replacement therapy.

  16. Presence and patterns of alkaline phosphatase activity and phosphorus cycling in natural riparian zones under changing nutrient conditions

    Directory of Open Access Journals (Sweden)

    Peifang Wang

    2014-08-01

    Full Text Available Phosphorus (P is an important limiting nutrient in aquatic ecosystems and knowledge of P cycling is fundamental for reducing harmful algae blooms and other negative effects in water. Despite their importance, the characteristics of P cycling under changing nutrient conditions in shallow lakes were poorly investigated. In this study, in situ incubation experiments were conducted in a natural riparian zone in the main diversion channel used for water transfer into Lake Taihu (Wangyu River. Variations in microbial biomass, dissolved P fractions (organic and inorganic, and alkaline phosphatase activity (bulk APA and specific APA were determined after incubation with and without the addition of P and nitrogen (N (4 total water treatments: +P, +N, +NP, and control. Experiments were conducted during two seasons (late spring and early fall to account for natural differences in nutrient levels that may occur in situ. Our results demonstrated that low levels of DRP may not necessarily indicate P limitation. Phytoplankton exhibited “serial N limitation with P stress” in May, such that chlorophyll a (Chl a increased significantly with N addition, while the limiting nutrient shifted to P in October and phytoplankton biomass increased with P addition. Phytoplankton contributed greatly to APA production and was significantly influenced by P bioavailability, yet high levels of bulk APA were also not necessarily indicative of P limitation. In contrast to phytoplankton, bacteria were less P stressed. As a consequence of enhanced utilization of dissolved reactive P (DRP and dissolved organic P (DOP, +N treatment elevated APA significantly. By contrast, APA could be repressed to low values and phytoplankton converted a large portion of DRP to DOP with P addition. But this was not consistent with bacteria APA (bact-APA in the absence or presence of abundant phytoplankton biomass. The correlation between bulk APA and DRP was good at separate sites and discrepant

  17. Alaska Power Administration combined financial statements, schedules, and supplemental reports, September 30, 1997 and 1996 with independent auditors` report thereon

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-04-01

    The Alaska Power Administration (APA) will continue to encourage economic and industrial development in Alaska through implementing the sale of APA assets in a manner consistent with the authorizing legislation while balancing all the stakeholders` interests. Alaska Power Administration will provide their employees opportunities for successful career transitions and conduct an efficient transfer of assets and closeout of APA, while continuing to provide customers reliable, low-cost hydroelectric energy during the transition. The attached report presents the results of the independent certified public accounts` audit of the Alaska Power Administration`s (APA) combined power system statements of assets; Federal investment and liabilities; and the related combined statements of revenues, expenses and accumulated net revenues, and cash flows. The auditors` reports on APA`s internal control structure and compliance with laws and regulations disclosed no reportable conditions or instances of noncompliance. Based on the unqualified opinion of the independent public accounting firm of KPMG Peak Marwick LLP and review of their audit work, the authors believe the financial statements fairly present the financial condition and results of the operations of APA for the period under audit.

  18. Protocol to assess the neurophysiology associated with multi-segmental postural coordination

    International Nuclear Information System (INIS)

    Lomond, Karen V; Henry, Sharon M; Jacobs, Jesse V; Hitt, Juvena R; Horak, Fay B; Cohen, Rajal G; Schwartz, Daniel; Dumas, Julie A; Naylor, Magdalena R; Watts, Richard; DeSarno, Michael J

    2013-01-01

    Anticipatory postural adjustments (APAs) stabilize potential disturbances to posture caused by movement. Impaired APAs are common with disease and injury. Brain functions associated with generating APAs remain uncertain due to a lack of paired tasks that require similar limb motion from similar postural orientations, but differ in eliciting an APA while also being compatible with brain imaging techniques (e.g., functional magnetic resonance imaging; fMRI). This study developed fMRI-compatible tasks differentiated by the presence or absence of APAs during leg movement. Eighteen healthy subjects performed two leg movement tasks, supported leg raise (SLR) and unsupported leg raise (ULR), to elicit isolated limb motion (no APA) versus multi-segmental coordination patterns (including APA), respectively. Ground reaction forces under the feet and electromyographic activation amplitudes were assessed to determine the coordination strategy elicited for each task. Results demonstrated that the ULR task elicited a multi-segmental coordination that was either minimized or absent in the SLR task, indicating that it would serve as an adequate control task for fMRI protocols. A pilot study with a single subject performing each task in an MRI scanner demonstrated minimal head movement in both tasks and brain activation patterns consistent with an isolated limb movement for the SLR task versus multi-segmental postural coordination for the ULR task. (note)

  19. Vascular complications in patients with aldosterone producing adenoma in Japan: comparative study with essential hypertension. The Research Committee of Disorders of Adrenal Hormones in Japan.

    Science.gov (United States)

    Takeda, R; Matsubara, T; Miyamori, I; Hatakeyama, H; Morise, T

    1995-05-01

    The incidence of vascular complications in 224 patients with aldosterone-producing adenoma (APA) which was proven on adrenal surgery, was compared to that in 224 sex- and age-matched patients with essential hypertension (EHT). The incidence of cerebral hemorrhage was significantly higher (p < 0.05) in the patients with APA when compared to the EHT group. On the other hand, the incidence of myocardial infarction and/or congestive heart failure in the APA group was lower, although this difference did not reach statistical significance. Diastolic blood pressure in the APA group was significantly higher (p < 0.001) in the EHT group. However, a significant difference in diastolic blood pressure was not detected between the APA groups with and without vascular complications, whereas in the EHT group diastolic blood pressure was significantly higher (p < 0.001) in cases with vascular complications as compared to those without complications. As a possible factor contributing to the higher incidence of cerebral hemorrhage in the APA group, proteinuria was suggested. It was recommended that patients with primary aldosteronism should undergo operation when localization of the APA is established.

  20. Dynamic Analyses of Alternative Polyadenylation from RNA-Seq Reveal 3′-UTR Landscape Across 7 Tumor Types

    Science.gov (United States)

    Xia, Zheng; Donehower, Lawrence A; Cooper, Thomas A.; Neilson, Joel R.; Wheeler, David A.; Wagner, Eric J.; Li, Wei

    2015-01-01

    Alternative polyadenylation (APA) is a pervasive mechanism in the regulation of most human genes, and its implication in diseases including cancer is only beginning to be appreciated. Since conventional APA profiling has not been widely adopted, global cancer APA studies are very limited. Here we develop a novel bioinformatics algorithm (DaPars) for the de novo identification of dynamic APAs from standard RNA-seq. When applied to 358 TCGA Pan-Cancer tumor/normal pairs across 7 tumor types, DaPars reveals 1,346 genes with recurrent and tumor-specific APAs. Most APA genes (91%) have shorter 3′ UTRs in tumors that can avoid miRNA-mediated repression, including glutaminase (GLS), a key metabolic enzyme for tumor proliferation. Interestingly, selected APA events add strong prognostic power beyond common clinical and molecular variables, suggesting their potential as novel prognostic biomarkers. Finally, our results implicate CstF64, an essential polyadenylation factor, as a master regulator of 3′ UTR shortening across multiple tumor types. PMID:25409906