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Sample records for apa

  1. APA Council Reports.

    Science.gov (United States)

    2017-10-01

    At the fall component meetings of the American Psychiatric Association in Arlington, Va., September 13-16, 2017, the APA councils heard reports from their components. Following are summaries of the activities of the councils and their components.

  2. Demystifying APA style.

    Science.gov (United States)

    Cuddy, Claudia M

    2002-01-01

    Many nursing schools and health care journals have adopted the Publication Manual of the American Psychological Association (APA stylebook) as their guide to achieve uniformity and consistency in manuscript preparation as well as in usage and writing style. Published in 2001, the fifth edition of the APA stylebook contains 440 pages and can overwhelm someone who tries to use it for the first time. This article delineates main points in the areas of manuscript preparation, reference lists, in-text citations, and style choices.

  3. APA Educational Psychology Handbook

    Science.gov (United States)

    Harris, Karen R., Ed.; Graham, Steve, Ed.; Urdan, Tim, Ed.

    2011-01-01

    The "APA Educational Psychology Handbook" reflects the broad nature of the field today, with state-of-the-science reviews of the diverse critical theories driving research and practice; in-depth investigation of the range of individual differences and cultural/contextual factors that affect student achievement, motivation, and beliefs;…

  4. Academic Practice, APA Referencing Style

    DEFF Research Database (Denmark)

    Nielsen, Sandro; Heine, Carmen

    kildeangivelse og referencer i henhold til APA referencing system.Vejledning i at undgå plagiering ved at følge de normer, der gælder for good academic practice. Dette indebærer at man angiver kilder korrekt, og når det er nødvendigt, og at man har en korrekt udformet fortegnelse over referencer. Vejledningen...... indeholder konkrete eksempler på korrekt kildeangivelse og referencer i henhold til APA referencing system....

  5. Recognition of psychotherapy effectiveness: the APA resolution.

    Science.gov (United States)

    Campbell, Linda F; Norcross, John C; Vasquez, Melba J T; Kaslow, Nadine J

    2013-03-01

    In August 2012, the American Psychological Association (APA) Council of Representatives voted overwhelmingly to adopt as APA policy a Resolution on the Recognition of Psychotherapy Effectiveness. This invited article traces the origins and intentions of that resolution and its protracted journey through the APA governance labyrinth. We summarize the planned dissemination and projected results of the resolution and identify several lessons learned through the entire process.

  6. Guide to APA-Based Models

    Science.gov (United States)

    Robins, Robert E.; Delisi, Donald P.

    2008-01-01

    In Robins and Delisi (2008), a linear decay model, a new IGE model by Sarpkaya (2006), and a series of APA-Based models were scored using data from three airports. This report is a guide to the APA-based models.

  7. Comprehending APA Style through Manuscript Analysis.

    Science.gov (United States)

    Smith, Gabie E.; Eggleston, Tami J.

    2001-01-01

    Describes an activity designed to enhance undergraduate student comprehension of the American Psychological Association (APA) manual and style where students examined a poorly written paper for errors in relation to the APA guidelines. Reports the results of a study that tested the effectiveness of the activity. (CMK)

  8. Sport and APA: proces of possible diffusion

    Directory of Open Access Journals (Sweden)

    Hana Válková

    2011-03-01

    Full Text Available Relation between Adapted Physical Activity (APA are described in the article. Recent sport professions as so as professions related to sports are formulated. "Coach" profession is defined with more details, the term "sport of persons with disability" is explained, too. On the bases of personal experience the APA domain which every coach can be touched are presented. Events which recent coaches, sports clubs in Czech Republic participated in are added. The basic questions of EUSAPA project are answered: regular sport and APA are blended together. Diffusion of sport and APA can become good platform for inclusion in life span context. Coaches should be informed about basic principles of APA according the level of connection (humanitarian domain - coaches in sports of disabled, the type of sport (relation to general sport and performance level (recreation - top competitive. The topic APA should be included on adequate level in education courses of coaches. The practice in sport activities of people with disability has to be involved.

  9. Aplicaciones Normas APA y sus tendencias

    OpenAIRE

    Ledesma-Ayora, Marco; Muñoz Cajilima, Néstor Xavier

    2016-01-01

    [ES] Este manual fue elaborado en base a las normas APA (American Psychological Association), actualización y el aporte como tendencias, el anhelo es que sea de beneficio para estudiantes, docentes e investigadores que aplican una buena escritura académica. Las normas APA es un conjunto de referencias para la escritura de trabajos, proyectos y publicaciones, proyectando así su validez y confiabilidad, que permiten visibilizar una correcta formalidad en la presentación, pudiendo ser mediado a ...

  10. Resolving a Conflict between APA Learning Goals and APA Ethical Principles

    Science.gov (United States)

    Corty, Eric W.

    2008-01-01

    Although American Psychological Association (APA) Ethical Standards make it clear that instructors cannot require students to disclose personal information in class-related activities, an APA learning goal for undergraduate psychology students is that they reflect on their experiences to develop insight into their behavior and mental processes.…

  11. Women's Participation in Behavioral and APA Journals.

    Science.gov (United States)

    Morris, Edward K.; And Others

    Concern about the professional socialization of women in academic positions has increased markedly in recent years. This study examined women's participation in behavioral journals and journals published by the American Psychological Association (APA) in terms of journal authorship and the composition of journal editorial boards. Behavioral…

  12. The APA Style Converter: a Web-based interface for converting articles to APA style for publication.

    Science.gov (United States)

    Li, Ping; Cunningham, Krystal

    2005-05-01

    The APA Style Converter is a Web-based tool with which authors may prepare their articles in APA style according to the APA Publication Manual (5th ed.). The Converter provides a user-friendly interface that allows authors to copy and paste text and upload figures through the Web, and it automatically converts all texts, references, and figures to a structured article in APA style. The output is saved in PDF or RTF format, ready for either electronic submission or hardcopy printing.

  13. APA, Meet Google: Graduate Students' Approaches to Learning Citation Style

    Science.gov (United States)

    Van Note Chism, Nancy; Weerakoon, Shrinika

    2012-01-01

    Inspired by Perkins' Theories of Difficulty concept, this exploratory study examined the learning patterns of graduate students as they grappled with using the style sheet of the American Psychological Association (APA). The researchers employed task performance analysis of three APA formatting tasks, interviews, and observation during a "think…

  14. Who Cares about APA Policy and Does it Have an Impact? 2006 Annual Report of the APA Policy and Planning Board

    Science.gov (United States)

    American Psychologist, 2007

    2007-01-01

    What constitutes American Psychological Association (APA) policy? How does it affect the everyday and professional lives of APA members? How personally aware are psychologists of APA policies? In this report, the APA explores these questions and provide some intriguing findings on the fate of policies developed through the APA's complicated and…

  15. Complexing properties of amide oxime of picolinic acid (APA). 1

    International Nuclear Information System (INIS)

    Oginski, M.; Zommer-Urbanska, S.; Joachimiak, J.; Koniarek, B.

    1983-01-01

    As a result of APA labelling with /sup 99m/Tc reduced by SnCl 2 at pH 1.9 about 90% of the /sup 99m/Tc-APA complex was obtained. Experiments in vivo were carried out on 10 Swiss mice with implanted Ehrlich tumor. After 8 days the /sup 99m/Tc-APA complex was administered i.p. The ADF ratio tumor:blood was 2.5. Renoscintigraphy showed that the decline of renal activity in the stage when excretion prevailed (phase III) was slow and of the cumulative nature. Simple synthesis, labelling and low toxity of APA are the factors that advocate further experiments in investigating its usefulness for diagnostics. (author)

  16. Psi Chi/APA Edwin B. Newman Graduate Research Award.

    Science.gov (United States)

    2017-12-01

    The Edwin B. Newman Graduate Research Award is sponsored jointly by Psi Chi, the national honor society in psychology, and the APA. The award is presented annually to the psychology graduate student who submits the best research paper that was published or presented at a national, regional, or state psychological association conference during the past calendar year. The Edwin B. Newman Graduate Research Award was established in 1979. The award was established to recognize young researchers at the beginning of their professional lives and to commemorate both the 50th anniversary of Psi Chi and the 100th anniversary of psychology as a science (dating from the founding of Wundt's laboratory). It was named for Dr. Edwin B. Newman, the first national president of Psi Chi (1929) and one of its founders. He was a prolific researcher and a long-time chair of the Department of Psychology at Harvard University. Newman was a member of APA's Board of Directors, served as recording secretary of the board from 1962 to 1967, and was parliamentarian for the APA Council of Representatives for many years. He served both Psi Chi and APA in a distinguished manner for half a century. The Edwin B. Newman Graduate Research Award is given jointly by Psi Chi and APA. Members of the 2017 Edwin B. Newman Award Committee were Shawn Carlton, PhD, Psi Chi representative; Christina Frederick-Recascino, PhD; John Norcross, PhD, APA representative; Karenna Malavanti, PhD, Psi Chi representative; Steven Kohn, PhD, Psi Chi representative; Warren Fass, PhD, Psi Chi representative; Chris Lovelace, PhD, Psi Chi representative; and Cathy Epkins, PhD, APA representative. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  17. APA efforts in promoting human rights and social justice.

    Science.gov (United States)

    Leong, Frederick T L; Pickren, Wade E; Vasquez, Melba J T

    2017-11-01

    This article reviews the American Psychological Association's (APA) efforts in promoting human rights and social justice. Beginning with a historical review of the conceptualizations of human rights and social justice, the social challenges that have faced the United States over time are discussed in relation to the APA's evolving mission and strategic initiatives enacted through its boards, committees, and directorates. From early efforts on the Board for Social and Ethical Responsibility in Psychology and the Board of Ethnic Minority Affairs to the establishment of the Public Interest Directorate, the APA's efforts to address these human rights and social justice challenges through its task force reports, guidelines, and policies are described. Specifically, issues related to diversity and underrepresentation of minority group members and perspective within the APA, as well as women's issues (prochoice, violence against women, sexualization of young girls, human trafficking) were central to these efforts. These minority groups included racial and ethnic minority groups; immigrants and refugees; lesbian, gay, bisexual, transgendered, and queer individuals; and those with disabilities. Later attention shifted to broader social justice challenges within a public health perspective, such as AIDS, obesity, and violence. Also included is a brief discussion of the Hoffman Report. The article ends with a discussion of future directions for the APA's efforts related to human rights and social justice related to health disparities, violent extremism, social inequality, migration, cultural and racial diversity, and an evidence-based approach to programming. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  18. Teaching APA Style Documentation: Discovery Learning, Scaffolding and Procedural Knowledge

    Science.gov (United States)

    Skeen, Thomas; Zafonte, Maria

    2015-01-01

    Students struggle with learning correct documentation style as found in the Publication Manual of the American Psychological Association and teachers are often at a loss for how to best instruct students in correct usage of APA style. As such, the first part of this paper discusses the current research on teaching documentation styles as well as…

  19. Instructional Strategies to Improve College Students' APA Style Writing

    Science.gov (United States)

    Mandernach, B. Jean; Zafonte, Maria; Taylor, Caroline

    2016-01-01

    The purpose of this study was to identify areas of APA formatting that college instructors view as most problematic in student writing. Using a Likert-style survey, the greatest areas of reported concern were problems with documentation, specifically, citations, references, and quoting; of lesser concern were various style and formatting errors in…

  20. Re-evaluation of characterisation and classification of Apa ( Afzelia ...

    African Journals Online (AJOL)

    As a result of effect of geographical location on timber properties, there is need for constant determination of properties of timber. This paper presents the results of experimental tests carried out on three Apa (Afzelia bipindensis) timber logs grown in Kwara State, south-western periphery of the North Central Zone of Nigeria ...

  1. Mastering the APA Style of Referencing with Ease | Omotosho ...

    African Journals Online (AJOL)

    Students and lecturers in tertiary institutions whose areas of specialization are in Education and the Social and Behavioural Sciences are required to apply the APA style whenever they submit their projects and papers. However, due to the fact that the Publication Manual of the American Psychological Association is very ...

  2. Rapid induction of glomerular lipidosis in APA hamsters by streptozotocin.

    Science.gov (United States)

    Han, J. S.; Sugawara, Y.; Doi, K.

    1992-01-01

    The pathology of male Syrian hamsters of APA strain which were injected intraperitoneally with 40 mg/kg body weight of streptozotocin (SZ) at 2 months of age was examined. It showed long-lasting prominent hyperglycaemia and hyperlipidaemia with glucosuria and the development of glomerular lipidosis from 1 month after SZ-injection (1 MAI). Glomerular lesions were restricted to the juxtamedullary cortex at 1 MAI and then extended to the subcapsular cortex. At 3 MAI, glomerular lesions were characterized by focal segmental glomerulosclerosis showing segmental expansion of the mesangial area due to an increase of basement membrane-like material and mesangial cells with lipid droplets and foam cells. SZ-induced diabetic APA hamsters will be a useful model for the investigation of glomerular lipidosis and focal segmental glomerulosclerosis. Images Fig. 3 Fig. 4 Fig. 5 Fig. 6 Fig. 7 Fig. 8 Fig. 9 PMID:1533531

  3. Quality control in preparation of APA microcapsular immune isolation biomembrane

    International Nuclear Information System (INIS)

    Li Xinjian; Xue Yilong; Lu Qingguo; Li Yanling; Gao Yuhong

    2005-01-01

    For optimization of preparation condition, simplification of technique and quality control, we observed partial physical and chemical factors in process of preparation of alginate-polylysine-alginate (APA) microcapsular immune isolation biomembrane. The result showed that granular diameter of the microcapsules was negatively correlated with pulse frequency of static microcapsule generator and positively correlated with speed of driving pump and bore of pinhead. The membrane thickness was remarkably increased with the increase of polylysine density. Prolonging reaction time of shaping membrane didn't change granular diameter of the microcapsules, but influenced membrane thickness. Liquefaction time of sodium citrate had no remarkable effect on granular diameter and membrane thickness. APA microcapsular immuno isolation biomembrane would have better permeability, flexibility, biological compatibility and intensity by optimizing preparation conditions. (authors)

  4. Gregory Daniel Webster: Psi Chi/APA Edwin B. Newman Graduate Research Award.

    Science.gov (United States)

    2006-11-01

    Presents a citation for Gregory Daniel Webster, who received the Psi Chi/APA Edwin B. Newman Graduate Research Award "for an outstanding research paper whose findings report that APA journal articles became shorter in length after the year 2000." A brief profile and a selected bibliography accompany the citation. ((c) 2006 APA, all rights reserved).

  5. 77 FR 38378 - Hours of Service (HOS) of Drivers; Revision of Exemption; American Pyrotechnics Association (APA)

    Science.gov (United States)

    2012-06-27

    ...-28043] Hours of Service (HOS) of Drivers; Revision of Exemption; American Pyrotechnics Association (APA... Pyrotechnics Association (APA) that were granted an exemption from FMCSA's prohibition on driving commercial...-July 8, inclusive, in 2011 and 2012. The exemption covered renewal of 53 APA-member motor carriers and...

  6. 76 FR 37876 - Hours of Service (HOS) of Drivers; Renewal of American Pyrotechnics Association (APA) Exemption...

    Science.gov (United States)

    2011-06-28

    ...-28043] Hours of Service (HOS) of Drivers; Renewal of American Pyrotechnics Association (APA) Exemption... announces the renewal of the exemption of specified members of the American Pyrotechnics Association (APA... of this exemption in effect, designated APA-member motor carriers will maintain a level of safety...

  7. 76 FR 30232 - Hours of Service (HOS) of Drivers; Application of American Pyrotechnics Association (APA) for...

    Science.gov (United States)

    2011-05-24

    ...-28043] Hours of Service (HOS) of Drivers; Application of American Pyrotechnics Association (APA) for... American Pyrotechnics Association (APA) has applied for a limited exemption from FMCSA's regulation that... exemption would apply solely to the operation of CMVs by 9 designated APA-member motor carriers in...

  8. 76 FR 37880 - Hours of Service (HOS) of Drivers; Granting of Exemption; American Pyrotechnics Association (APA)

    Science.gov (United States)

    2011-06-28

    ...-28043] Hours of Service (HOS) of Drivers; Granting of Exemption; American Pyrotechnics Association (APA... exemption from the American Pyrotechnics Association (APA) on behalf of 9 member motor carriers seeking... such exemption'' (49 U.S.C. 31315(b)(1)). The initial APA application for waiver or exemption relief...

  9. The APR1400 Core Design by Using APA Code System

    International Nuclear Information System (INIS)

    Choi, Yu Sun; Koh, Byung Marn

    2008-01-01

    The nuclear design for APR1400 has been performed to prepare the core model for Automatic Load Follow Operation Simulation. APA (ALPHA/ PHOENIXP/ ANC) code system is a tool for the multi-cycle depletion calculations for APR1400. Its detail versions for ALPHA, PHOENIX-P and ANC are 8.9.3, 8.6.1 and 8.10.5, respectively. The first and equilibrium core depletion calculations for APR1400 have been performed to assure the target cycle length and confirm the safety parameters. The parameters are satisfied within limitation about nuclear design criteria. This APR1400 core models will be based on the design parameters for APR1400 Simulator

  10. Decission Support System (DSS dalam Auditing Untuk Apa Digunakan

    Directory of Open Access Journals (Sweden)

    Priyono Puji Prasetyo

    2015-12-01

    Full Text Available Komputer semakin sering digunakan pada kantor akuntan. Tidak hanya digunakan untuk menggantikan kegiatan yang bersifat manual, tetapi juga sebagai alat bantu bagi akuntan dalam pengambilan keputusan. Keputusan yang dibuat dengan dukungan (decision support sistem komputer ini diharapkan tidak hanya akan lebih efisien, tetapi juga lebih efektif dalam mencapai tujuan. Konsekuensi-nya, bantuan semacam itu memperoleh dukungan yang luas untuk digunakan dalam auditing dan bidang pekerjaan lainnya. Apa yang menyebabkan Decision Support System (DSS digunakan adalah kemampuannya membantu akuntan dalam proses pembuatan keputusan audit. Alat ini perlu dipergunakan oleh akuntan karena profesi akuntansi berhadapan dengan pasar yang semakin besar, saingan yang lebih ketat serta tekanan hukum, sehingga auditor independen dituntut untuk mengembangkan kualitas pelayanan audit dengan harga yang lebih kompetitif.Tulisan ini bertujuan untuk membahas penggunaan Decision Support System (DSS dalam auditing. Pembahasan akan dimulai dengan sejarah perkembangan komputer yang kemudian disusul dengan uraian tentang decision support system (DSS. Uraian yang agak luas mengenai penggunaan DSS dalam auditing diberikan pada seksi berikutnya. Berdasarkan uraian mengenai DSS tersebut akan diberikan kesimpulan untuk mengakhiri tulisan ini.

  11. Guide för referenshantering : APA-manual inom Barn- och ungdomsvetenskap (BUVA)

    OpenAIRE

    Engdahl, Ingrid

    2014-01-01

    Denna guide behandlar först hur du enligt APA refererar i löpande text och därefter hur man skriver en referenslista. För en komplett guide till APA Style hänvisas till Publication Manual of the American Psychological Association (American Psychological Association, 2010) eller till hemsidan http://www.apastyle.org, där det finns tydlig introduktion i ljud och bild till APA Style.

  12. Apa is a trimeric autotransporter adhesin of Actinobacillus pleuropneumoniae responsible for autoagglutination and host cell adherence.

    Science.gov (United States)

    Xiao, Longwen; Zhou, Liang; Sun, Changjiang; Feng, Xin; Du, ChongTao; Gao, Yu; Ji, Qun; Yang, Shuxin; Wang, Yu; Han, Wenyu; Langford, P R; Lei, Liancheng

    2012-10-01

    Actinobacillus pleuropneumoniae is the causative agent of porcine pleuropneumonia, and adherence to host cells is a key step in the pathogenic process. Although trimeric autotransporter adhesins (TAAs) were identified in many pathogenic bacteria in recent years, none in A. pleuropneumoniae have been characterized. In this study, we identified a TAA from A. pleuropneumoniae, Apa, and characterized the contribution of its amino acid residues to the adhesion process. Sequence analysis of the C-terminal amino acid residues of Apa revealed the presence of a putative translocator domain and six conserved HsfBD1-like or HsfBD2-like binding domains. Western blot analysis revealed that the 126 C-terminal amino acids of Apa could form trimeric molecules. By confocal laser scanning microscopy, one of these six domains (ApaBD3) was determined to mediate adherence to epithelial cells. Adherence assays and adherence inhibition assays using a recombinant E. coli- ApaBD3 strain which expressed ApaBD3 on the surface of E. coli confirmed that this domain was responsible for the adhesion activity. Moreover, cellular enzyme-linked immunosorbent assays demonstrated that ApaBD3 mediated high-level adherence to epithelial cell lines. Intriguingly, autoagglutination was observed with the E. coli- ApaBD3 strain, and this phenomenon was dependent upon the association of the expressed ApaBD3 with the C-terminal translocator domain. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Information Technology & Applications Corporation v. United States: An Interested Party's "Substantial Chance" at APA Standing

    National Research Council Canada - National Science Library

    Slicker, Christina

    2003-01-01

    .... Building on CICA's "interested party" definition with Information Technology's refinement of "substantial chance" rule, the Federal Circuit has effectively translated "APA standing" into the language...

  14. Identification of the Mycobacterium marinum Apa antigen O-mannosylation sites reveals important glycosylation variability with the M. tuberculosis Apa homologue.

    Science.gov (United States)

    Coddeville, Bernadette; Wu, Sz-Wei; Fabre, Emeline; Brassart, Colette; Rombouts, Yoann; Burguière, Adeline; Kremer, Laurent; Khoo, Kay-Hooi; Elass-Rochard, Elisabeth; Guérardel, Yann

    2012-10-22

    The 45/47 kDa Apa, an immuno-dominant antigen secreted by Mycobacterium tuberculosis is O-mannosylated at multiple sites. Glycosylation of Apa plays a key role in colonization and invasion of the host cells by M. tuberculosis through interactions of Apa with the host immune system C-type lectins. Mycobacterium marinum (M.ma) a fish pathogen, phylogenetically close to M. tuberculosis, induces a granulomatous response with features similar to those described for M. tuberculosis in human. Although M.ma possesses an Apa homologue, its glycosylation status is unknown, and whether this represents a crucial element in the pathophysiology induced by M.ma remains to be addressed. To this aim, we have identified two concanavalin A-reactive 45/47 kDa proteins from M.ma, which have been further purified by a two-step anion exchange chromatography process. Advanced liquid chromatography-nanoESI mass spectrometry-based proteomic analyses of peptides, derived from either tryptic digestion alone or in combination with the Asp-N endoproteinase, established that M.ma Apa possesses up to seven distinct O-mannosylated sites with mainly single mannose substitutions, which can be further extended at the Ser/Thr/Pro rich region near the N-terminus. This opens the way to further studies focussing on the involvement and biological functions of Apa O-mannosylation using the M.ma/zebrafish model. Copyright © 2012 Elsevier B.V. All rights reserved.

  15. The Language of Scholarship: How to Rapidly Locate and Avoid Common APA Errors.

    Science.gov (United States)

    Freysteinson, Wyona M; Krepper, Rebecca; Mellott, Susan

    2015-10-01

    This article is relevant for nurses and nursing students who are writing scholarly documents for work, school, or publication and who have a basic understanding of American Psychological Association (APA) style. Common APA errors on the reference list and in citations within the text are reviewed. Methods to quickly find and reduce those errors are shared. Copyright 2015, SLACK Incorporated.

  16. The Impact of APA and AERA Guidelines on Effect Size Reporting

    Science.gov (United States)

    Peng, Chao-Ying Joanne; Chen, Li-Ting; Chiang, Hsu-Min; Chiang, Yi-Chen

    2013-01-01

    Given the long history of effect size (ES) indices (Olejnik and Algina, "Contemporary Educational Psychology," 25, 241-286 2000) and various attempts by APA and AERA to encourage the reporting and interpretation of ES to supplement findings from inferential statistical analyses, it is essential to document the impact of APA and AERA standards on…

  17. Investigation of the Asphalt Pavement Analyzer (APA) testing program in Nebraska.

    Science.gov (United States)

    2008-03-01

    The asphalt pavement analyzer (APA) has been widely used to evaluate hot-mix asphalt (HMA) rutting potential in mix : design and quality control-quality assurance (QC-QA) applications, because the APA testing and its data analyses are : relatively si...

  18. Teaching Scientific Writing: Measuring Student Learning in an Intensive APA Skills Course

    Science.gov (United States)

    Luttrell, Vickie R.; Bufkin, Jana L.; Eastman, Valerie J.; Miller, Robin

    2010-01-01

    The "Publication Manual of the American Psychological Association" (American Psychological Association [APA], 2010) provides a widely utilized template for preparing research reports in the behavioral sciences. Because learning APA style is integral to disciplinary socialization, our department recently implemented a 1-hr course in scientific…

  19. In-vitro analysis of APA microcapsules for oral delivery of live bacterial cells.

    Science.gov (United States)

    Chen, H; Ouyang, W; Jones, M; Haque, T; Lawuyi, B; Prakash, S

    2005-08-01

    Oral administration of microcapsules containing live bacterial cells has potential as an alternative therapy for several diseases. This article evaluates the suitability of the alginate-poly-L-lysine-alginate (APA) microcapsules for oral delivery of live bacterial cells, in-vitro, using a dynamic simulated human gastro-intestinal (GI) model. Results showed that the APA microcapsules were morphologically stable in the simulated stomach conditions, but did not retain their structural integrity after a 3-day exposure in simulated human GI media. The microbial populations of the tested bacterial cells and the activities of the tested enzymes in the simulated human GI suspension were not substantially altered by the presence of the APA microcapsules, suggesting that there were no significant adverse effects of oral administration of the APA microcapsules on the flora of the human gastrointestinal tract. When the APA microcapsules containing Lactobacillus plantarum 80 (LP80) were challenged in the simulated gastric medium (pH = 2.0), 80.0% of the encapsulated cells remained viable after a 5-min incubation; however, the viability decreased considerably (8.3%) after 15 min and dropped to 2.6% after 30 min and lower than 0.2% after 60 min, indicating the limitations of the currently obtainable APA membrane for oral delivery of live bacteria. Further in-vivo studies are required before conclusions can be made concerning the inadequacy of APA microcapsules for oral delivery of live bacterial cells.

  20. APA/APAGS Award for Distinguished Graduate Student in Professional Psychology: Octavio Andres Santos.

    Science.gov (United States)

    2017-12-01

    The APA/APAGS Award for Distinguished Graduate Student in Professional Psychology is awarded annually by the APA Board of Professional Affairs (BPA) and the American Psychological Association of Graduate Students (APAGS) to a graduate student who has demonstrated outstanding practice and application of psychology. The 2017 award winner is Octavio Andres Santos, who has demonstrated through several initiatives "effective engagement with advocacy, professional organizations, and research in the area of health disparities and multicultural/multilingual assessment." Santos's award citation, biography, and a selected bibliography are presented here. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  1. Adam M. Reid: APA/APAGS Award for Distinguished Graduate Student in Professional Psychology.

    Science.gov (United States)

    2015-11-01

    The APA/APAGS Award for Distinguished Graduate Student in Professional Psychology is awarded on an annual basis by the APA Board of Professional Affairs (BPA) and the American Psychological Association of Graduate Students (APAGS) to a graduate student who has demonstrated outstanding practice and application of psychology. One of the 2015 award winners is Adam M. Reid, who received this award "for his community service, in which he has integrated the highest standards of professional psychological clinical practice and science." Adam's award citation, biography, and a selected bibliography are presented here. (c) 2015 APA, all rights reserved).

  2. APA/APAGS Award for Distinguished Graduate Student in Professional Psychology: Luz Maria Garcini.

    Science.gov (United States)

    2016-11-01

    The APA/APAGS Award for Distinguished Graduate Student in Professional Psychology is awarded on an annual basis by the APA Board of Professional Affairs (BPA) and the American Psychological Association of Graduate Students (APAGS) to a graduate student who has demonstrated outstanding practice and application of psychology. The 2016 award winners is Luz Maria Garcini, whose commitment to the health and mental health of those recently immigrated has led to research and service that "have greatly benefited the lives of undocumented individuals in the border area of southern California." Garcini's award citation, biography, and a selected bibliography are presented here. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  3. Biomaterials for the programming of cell growth in oral tissues: The possible role of APA.

    Science.gov (United States)

    Salerno, Marco; Giacomelli, Luca; Larosa, Claudio

    2011-01-06

    Examples of programmed tissue response after the interaction of cells with biomaterials are a hot topic in current dental research. We propose here the use of anodic porous alumina (APA) for the programming of cell growth in oral tissues. In particular, APA may trigger cell growth by the controlled release of specific growth factors and/or ions. Moreover, APA may be used as a scaffold to promote generation of new tissue, due to the high interconnectivity of pores and the high surface roughness displayed by this material.

  4. [Exercise-referral to a specialist in adapted physical activity (APA) : a pilot project].

    Science.gov (United States)

    Brugnerotto, Adeline; Cardinaux, Regula; Ueltschi, Yan; Bauwens, Marine; Nanchen, David; Cornuz, Jacques; Bize, Raphaël; Auer, Reto

    2016-11-02

    Family physicians have a key role in the promotion of physical activity, in particular in identifying and counseling persons who have a sedentary lifestyle. Some patients could benefit from intensive individual counseling. Physicians are often not aware of all physical activity promotion activities in the community that they could recommend their patients. In a pilot study, we have tested and adapted the referral of patients from family physicians to specialists in adapted physical activity (APAs). APAs are trained to assess and guide persons towards physical activities adapted to their needs and pathologies and thus towards an increase in physical activity. Pilot data suggest that, while few patients were oriented to the APAs in the pilot project, family physicians appreciate the possibility of collaborating with the APAs.

  5. Michael K. Scullin: Psi Chi/APA Edwin B. Newman Graduate Research Award.

    Science.gov (United States)

    2011-11-01

    Presents Michael K. Scullin as the 2011 winner of the American Psychological Association Psi Chi/APA Edwin B. Newman Graduate Research Award. "For an outstanding research paper that examines the relationship between prospective memory in executing a goal and various lapses of time from 20 minutes up to a 12- hour wake delay and a 12-hour sleep delay. The results suggest that consolidation processes active during sleep increase the probability of goal execution. The paper, titled 'Remembering to Execute a Goal: Sleep On It!' was published in Psychological Science in 2010 and was the basis for Michael K. Scullin's selection as the recipient of the 2011 Psi Chi/APA Edwin B. Newman Graduate Research Award. Mark A. McDaniel, PhD, served as faculty research advisor." (PsycINFO Database Record (c) 2011 APA, all rights reserved). 2011 APA, all rights reserved

  6. Linkage disequilibrium at the APA insecticidal seed protein locus of common bean (Phaseolus vulgaris L.).

    Science.gov (United States)

    Blair, Matthew W; Prieto, Sergio; Díaz, Lucy M; Buendía, Héctor F; Cardona, César

    2010-04-29

    An interesting seed protein family with a role in preventing insect herbivory is the multi-gene, APA family encoding the alpha-amylase inhibitor, phytohemagglutinin and arcelin proteins of common bean (Phaseolus vulgaris). Variability for this gene family exists and has been exploited to breed for insect resistance. For example, the arcelin locus has been successfully transferred from wild to cultivated common bean genotypes to provide resistance against the bruchid species Zabrotes subfasciatus although the process has been hampered by a lack of genetic tools for and understanding about the locus. In this study, we analyzed linkage disequilibrium (LD) between microsatellite markers at the APA locus and bruchid resistance in a germplasm survey of 105 resistant and susceptible genotypes and compared this with LD in other parts of the genome. Microsatellite allele diversity was found to vary with each of the eight APA-linked markers analyzed, and two markers within the APA locus were found to be diagnostic for bruchid resistance or susceptibility and for the different arcelin alleles inherited from the wild accessions. Arc1 was found to provide higher levels of resistance than Arc5 and the markers in the APA locus were highly associated with resistance showing that introgression of this gene-family from wild beans provides resistance in cultivated beans. LD around the APA locus was found to be intermediate compared to other regions of the genome and the highest LD was found within the APA locus itself for example between the markers PV-atct001 and PV-ag004. We found the APA locus to be an important genetic determinant of bruchid resistance and also found that LD existed mostly within the APA locus but not beyond it. Moderate LD was also found for some other regions of the genome perhaps related to domestication genes. The LD pattern may reflect the introgression of arcelin from the wild into the cultivated background through breeding. LD and association studies for

  7. APA Handbook of Industrial and Organizational Psychology. Three-Volume Set--Volume 1: Building and Developing the Organization. Volume 2: Selecting and Developing Members for the Organization. Volume 3: Maintaining, Expanding, and Contracting the Organization. APA Handbooks in Psychology Series. APA Reference Books Collection

    Science.gov (United States)

    Zedeck, Sheldon, Ed.

    2011-01-01

    APA Books® announces the "APA Handbook of Industrial and Organizational Psychology"--the first offering in an new reference series covering core and emerging subdisciplines, the "APA Handbooks in Psychology." I/O Psychology is both a science/practice and an applied/basic research discipline. Appropriately, the "APA…

  8. [Apa1 VDR polymorphism and osteoporosis risk in postmenopausal Mexican women].

    Science.gov (United States)

    Castelán-Martínez, Osvaldo D; Vivanco-Muñoz, Nalleli; Falcón-Ramírez, Edith; Valdés-Flores, Margarita; Clark, Patricia

    2015-01-01

    To analyze the association between Apa1 VDR polymorphism and osteoporosis in Mexican mestizo postmenopausal women. A cross-sectional study was conducted in 534 postmenopausal mestizo women from Mexico City to determine the association of the Apa1 Vitamin D Receptor gene polymorphism (rs7975232) with osteoporosis and osteoporosis plus fracture. Bone mineral density (BMD) was assessed using dual-energy X-ray absorptiometry. Genotyping was performed using real-time PCR with an allelic discrimination assay. The Apa1 allele frequencies were no different between groups. No association was found between Apa1 genotypes and osteoporosis (AA, OR: 1.08; 95% CI: 0.62-1.87; AC, OR: 0.70; 95% CI: 0.45-1.07). Similar results were obtained for osteoporosis plus fracture (AA, OR: 0.93; 95% CI: 0.50-1.71; AC, OR: 0.70; 95% CI 0.45-1.07). After adjusting for age, the result remained. These findings are in agreement with previous studies reporting no association of Apa1 VDR polymorphism with osteoporosis.

  9. Biological changes of APA-BCC analgesic microcapsule in cerebrospinal fluid of patients with carcinomatous pain

    International Nuclear Information System (INIS)

    Luo Yun; Li Yanling; Xue Yilong; Guo Shulong; Gao Yuhong; Cui Xin

    2005-01-01

    To explore the changes of alginate-polylysine-alginate microcapsulated bovine adrenal medullary chromaffin cells (APA-BCC microcapsules) in morphology, survival rate and leucine- enkephalin secretion after they were transplanted into CSF of cancerpain patients, the APA- BCC microcapsules were Implanted into cavitas subarachnoidealis of cancer-pain patients by conventional lumbar puncture. After 7 or 8 days, cerebrospinal fluid was collected and the morphology of the APA-BCC microcapsule, the survival rate of cells were observed and secretory volume of leucine-enkephalin was assayed by radioimmunity method. Seven days after trans- plantation, the mean VAS decreased from 8.8 to 2.4, the survival rate of cells averagely reduced from 91.2% to 89.1%, morphology of APA-BCC microcapsules did not change obviously and secretory volume of leucine-enkephalin went up 1.65 times compared with that at pretrans- plantation. In conclusion, APA-BCC can survive, secret leucine-enkephalin and produce analgesic effect after transplanted into CSF of cancer-patients. (authors)

  10. Plutonium and minor actinides recycling in PWRs with new APA concepts

    International Nuclear Information System (INIS)

    Golfier, H.; Rohart, M.; Aniel, S.; Bergeron, J.; Deffain, J.P.

    2001-01-01

    In the frame of the studies required by the French law of 1991, CEA have launched a wide range of assessments on waste management for different reactors (PWR, FBR). Considerable R and D work has already been performed in order to improve the use of Plutonium (Pu) in PWRs. In this context, the Advanced Plutonium Assembly (APA) aims to improve the use of Plutonium (Pu) in PWRs while minimizing Minor Actinides (MA) production, with only slight modifications of the core design. From a neutronic point of view, the overall studied cases lead to the stabilization of the Pu inventory with approximately 30% of the park refueled with APA assemblies in full APA cores. Multi-recycling could satisfy the stabilization of Pu+ (Am+Cm) inventory by the implementation of approximately 40% APA reactors in a conventional PWRs park. After 7 or 8 recycles, the equilibrium is reached. The Pu inventory in the fuel cycle ranges from 210 tons to 270 tons for Pu multi-recycling, and from 240 tons to 290 tons for Pu+(Am+Cm) multi-recycling. The saving in Natural Uranium and Separative Work Units (SWU) due to the use of APA reactors would be between 30% and 15% in comparison with the UO 2 open cycle. This paper presents a selection of the main preliminary Pu recycling results of the joint study program COGEMA-CEA. (author)

  11. Rebeccah A. Bernard: APA/APAGS Award for Distinguished Graduate Student in Professional Psychology.

    Science.gov (United States)

    2014-11-01

    The APA/APAGS Award for Distinguished Graduate Student in Professional Psychology is awarded on an annual basis by the APA Board of Professional Affairs (BPA) and the American Psychological Association of Graduate Students (APAGS) to a graduate student who has demonstrated outstanding practice and application of psychology. A qualified candidate must demonstrate exemplary performance in working with an underserved population in an applied setting or have developed an innovative method for delivering health services to an underserved population. This year there are joint recipients of the award, Allie Abrahamson and Rebeccah A. Bernard. Their vision, creativity, courage, and dedication led them to create the Human Rights Forum at Chestnut Hill College to promote human rights education, awareness, and community service opportunities for doctoral students. Rebeccah A. Bernard's award citation, biography, and a selected bibliography are presented here. PsycINFO Database Record (c) 2014 APA, all rights reserved.

  12. Allie Abrahamson: APA/APAGS Award for Distinguished Graduate Student in Professional Psychology.

    Science.gov (United States)

    2014-11-01

    The APA/APAGS Award for Distinguished Graduate Student in Professional Psychology is awarded on an annual basis by the APA Board of Professional Affairs (BPA) and the American Psychological Association of Graduate Students (APAGS) to a graduate student who has demonstrated outstanding practice and application of psychology. A qualified candidate must demonstrate exemplary performance in working with an underserved population in an applied setting or have developed an innovative method for delivering health services to an underserved population. This year there are joint recipients of the award, Allie Abrahamson and Rebeccah A. Bernard. Their vision, creativity, courage, and dedication led them to create the Human Rights Forum at Chestnut Hill College to promote human rights education, awareness, and community service opportunities for doctoral students. Allie Abrahamson's award citation, biography, and a selected bibliography are presented here. PsycINFO Database Record (c) 2014 APA, all rights reserved.

  13. Jordan M. Braciszewski: APA/APAGS Award for Distinguished Graduate Student in Professional Psychology.

    Science.gov (United States)

    2011-11-01

    Presents Jordan M. Braciszewski as the 2011 winner of the American psychological Association APA/APAGS Award for Distinguished Graduate Student in Professional Psychology. "For his concerted efforts to identify the needs of homeless and other at-risk populations and to design and provide necessary services for them. Jordan M. Braciszewski is committed to using applied psychological science and evidence-based intervention methods to assist the most disadvantaged in our society. He has already provided additions to the relevant research literature and has volunteered countless hours of his time to implement community-based interventions and provide direct services himself. He has sought out the training experiences necessary to assist him in doing an even better job in the future in these public service activities." (PsycINFO Database Record (c) 2011 APA, all rights reserved). 2011 APA, all rights reserved

  14. Molecular Regulation of Alternative Polyadenylation (APA) within the Drosophila Nervous System.

    Science.gov (United States)

    Vallejos Baier, Raul; Picao-Osorio, Joao; Alonso, Claudio R

    2017-10-27

    Alternative polyadenylation (APA) is a widespread gene regulatory mechanism that generates mRNAs with different 3'-ends, allowing them to interact with different sets of RNA regulators such as microRNAs and RNA-binding proteins. Recent studies have shown that during development, neural tissues produce mRNAs with particularly long 3'UTRs, suggesting that such extensions might be important for neural development and function. Despite this, the mechanisms underlying neural APA are not well understood. Here, we investigate this problem within the Drosophila nervous system, focusing on the roles played by general cleavage and polyadenylation factors (CPA factors). In particular, we examine the model that modulations in CPA factor concentration may affect APA during development. For this, we first analyse the expression of the Drosophila orthologues of all mammalian CPA factors and note that their expression decreases during embryogenesis. In contrast to this global developmental decrease in CPA factor expression, we see that cleavage factor I (CFI) expression is actually elevated in the late embryonic central nervous system, suggesting that CFI might play a special role in neural tissues. To test this, we use the UAS/Gal4 system to deplete CFI proteins from neural tissue and observe that in this condition, multiple genes switch their APA patterns, demonstrating a role of CFI in APA control during Drosophila neural development. Furthermore, analysis of genes with 3'UTR extensions of different length leads us to suggest a novel relation between 3'UTR length and sensitivity to CPA factor expression. Our work thus contributes to the understanding of the mechanisms of APA control within the developing central nervous system. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  15. Aquatic toxicity and biodegradability of advanced cationic surfactant APA-22 compatible with the aquatic environment.

    Science.gov (United States)

    Yamane, Masayuki; Toyo, Takamasa; Inoue, Katsuhisa; Sakai, Takaya; Kaneko, Youhei; Nishiyama, Naohiro

    2008-01-01

    Cationic surfactant is a chemical substance used in hair conditioner, fabric softener and other household products. By investigating the relationship between the aquatic toxicity and the chemical structures of two types of mono alkyl cationic surfactants, alkyl trimethylammonium salts and alkyl dimethylamine salts, we have found that the C22 alkyl chain length is effective to reduce the toxicity. Besides, we have recognized that the amidopropyl functional group contributes to the enhanced biodegradability by investigating the biodegradation trend of (alkylamidopropyl)dimethylamine salt (alkyl chain length: C18). Based on these findings, we have developed mono alkyl cationic surfactant called APA-22, N-[3-(dimethylamino)propyl]docosanamide salt. APA-22 is formed by the C22 alkyl chain, amidopropyl functional group and di-methyltertiary amine group. We evaluated the aerobic and anaerobic biodegradability of APA-22 by two standard methods (OECD Test Guideline 301B and ECETOC technical document No.28) and found that this substance was degraded rapidly in both conditions. The toxicity to algae, invertebrate and fish of this substance are evaluated by using OECD Test Guideline 201, 202 and 203, respectively. All acute toxicity values are >1 mg/L, which indicates that environmental toxicity of this substance is relatively less toxic to aquatic organism. In addition, we estimated the biodegradation pathway of APA-22 and observed the complete disappearance of APA-22 and its intermediates during the test periods. Based on the environmental data provided above, we concluded that APA22 is more compatible with the aquatic environment compared to other cationic surfactants with mono long alkyl chain.

  16. Connor H. G. Patros: Psi Chi/APA Edwin B. Newman Graduate Research Award.

    Science.gov (United States)

    2015-11-01

    The Edwin B. Newman Graduate Research Award is given jointly by Psi Chi and APA. The award was established to recognize young researchers at the beginning of their professional lives and to commemorate both the 50th anniversary of Psi Chi and the 100th anniversary of psychology as a science (dating from the founding of Wundt's laboratory). The 2015 recipient is Connor H. G Patros. Patros was chosen for "an excellent research paper that examines the complex relationship between working memory, choice-impulsivity, and the attention-deficit/hyperactivity disorder (ADHD) phenotype." Patros's award citation, biography, and a selected bibliography are presented here. (c) 2015 APA, all rights reserved).

  17. APA Reporting Standards in Quantitative Research Dissertations from an Online EdD Program

    Science.gov (United States)

    Salgado, Griselle

    2013-01-01

    This study was an investigation of the reporting practices in dissertations with quantitative research designs produced by students enrolled in an online Doctor of Education (EdD) program, one that follows the American Psychological Association (APA) standards for reporting research. Limited, empirical information exists about the competencies in…

  18. APA/APAGS Award for Distinguished Graduate Student in Professional Psychology.

    Science.gov (United States)

    2017-12-01

    The APA/APAGS Award for Distinguished Graduate Student in Professional Psychology is awarded on an annual basis by the APA Board of Professional Affairs (BPA) and the American Psychological Association of Graduate Students (APAGS) to a graduate student who has demonstrated outstanding practice and application of psychology. A qualified candidate must demonstrate exemplary performance in working with an underserved population in an applied setting or have developed an innovative method for delivering health services to an underserved population. The 2017 recipient of the APA/APAGS Award for Distinguished Graduate Student in Professional Psychology was selected by the 2016 Board of Professional Affairs (BPA) and the 2016 APAGS Scholarship and Awards Selection Committee. Members of the 2016 BPA were Antonette M. Zeiss, PhD (Chair); Linda A. Reddy, PhD; Lois O. Condie, PhD; Timothy A. Cavell, PhD; Robert T. Kinscherff, PhD, JD; Jared L. Skillings, PhD, ABPP; Cynthia A. Gómez, PhD; Lisa K. Kearney, PhD, ABPP; and Dinelia Rosa, PhD. Members of the 2016 APAGS Scholarship and Awards Selection Committee were Jerrold Yeo, MA; Jacklynn Fitzgerald, MA; and Roseann Fish Getchell, MA, Med. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  19. Cynthia J. Najdowski: Psi Chi/APA Edwin B. Newman Graduate Research Award

    Science.gov (United States)

    American Psychologist, 2012

    2012-01-01

    Presents a short biography of the winner of the American Psychological Association's Psi Chi/APA Edwin B. Newman Graduate Research Award. The 2012 winner is Cynthia J. Najdowski for an outstanding research paper that examines how jurors' judgments are influenced by a juvenile defendant's confession and status as intellectually disabled. Through…

  20. Internship Attainment and Program Policies: Trends in APA-Accredited School Psychology Programs

    Science.gov (United States)

    Perfect, Michelle M.; Thompson, Miriam E.; Mahoney, Emery

    2015-01-01

    Completion of an internship that is accredited by the American Psychological Association (APA) is considered to be to the "gold standard" for health service psychology training programs. The Association of Psychology Postdoctoral and Internship Centers (APPIC) facilitates a Match process between participating applicants and internship…

  1. Effects of an Interteaching Probe on Learning and Generalization of American Psychological Association (APA) Style

    Science.gov (United States)

    Slezak, Jonathan M.; Faas, Caitlin

    2017-01-01

    This study implemented the components of interteaching as a probe to teach American Psychological Association (APA) Style to undergraduate university students in a psychology research methods and statistics course. The interteaching method was compared to the traditional lecture-based approach between two sections of the course with the same…

  2. Scholarly Productivity and Impact of School Psychology Faculty in APA-Accredited Programs

    Science.gov (United States)

    Grapin, Sally L.; Kranzler, John H.; Daley, Matt L.

    2013-01-01

    The primary objective of this study was to conduct a normative assessment of the research productivity and scholarly impact of tenured and tenure-track faculty in school psychology programs accredited by the American Psychological Association (APA). Using the PsycINFO database, productivity and impact were examined for the field as a whole and by…

  3. Research Productivity and Scholarly Impact of APA-Accredited School Psychology Programs: 2005-2009

    Science.gov (United States)

    Kranzler, John H.; Grapin, Sally L.; Daley, Matt L.

    2011-01-01

    This study examined the research productivity and scholarly impact of faculty in APA-accredited school psychology programs using data in the PsycINFO database from 2005 to 2009. We ranked doctoral programs on the basis of authorship credit, number of publications, and number of citations. In addition, we examined the primary publication outlets of…

  4. Utilizaci??n de la normativa APA 6?? edici??n

    OpenAIRE

    Justicia-Arr??ez, Ana

    2016-01-01

    Tomando como referencia la normativa APA en su 6?? edici??n publicada en 2010 en el Manual of the American Psychological Association (6th ed.) por la American Psychological Association, se presenta una gu??a pr??ctica dirigida al alumnado de Ciencias de la Educaci??n.

  5. Psi Chi/APA Edwin B. Newman Graduate Research Award: Joseph H. Hammer

    Science.gov (United States)

    American Psychologist, 2009

    2009-01-01

    Joseph H. Hammer, recipient of the Psi Chi/APA Edwin B. Newman Graduate Research Award, is cited for an outstanding research paper whose findings provide important evidence regarding the promise of a male-sensitive approach to mental health marketing and empirically support the inclusion of theory-driven enhancements in group-targeted mental…

  6. Mechanisms of plant growth promotion and disease suppression by Pseudomonas aeruginosa strain 2apa.

    Science.gov (United States)

    Hariprasad, P; Chandrashekar, S; Singh, S Brijesh; Niranjana, S R

    2014-08-01

    A new Pseudomonas strain, designated as 2apa was isolated from tomato rhizosphere and identified as a member of species Pseudomonas aeruginosa based on its morphology, conventional, biochemical, cell wall fatty acid methyl ester analysis, and 16S rRNA gene sequence analysis. The strain 2apa was positive for root colonization, indole acetic acid (IAA), salicylic acid and siderophore production and inhibited the growth of wide range of microorganisms. Antimicrobial substances produced by this strain with further purification and structure elucidation proved to be phenazine. Under laboratory and greenhouse conditions the strain promoted plant growth and suppressed a wide range of foliar and root pathogens in tomato. The protection offered by strain 2apa to foliar pathogens is considered as induced systemic resistance and was further confirmed by enhanced accumulation of phenolics, elicitation of lipoxygenas activity, and jasmonic acid levels. The broad-spectrum antimicrobial and induced systemic resistance exhibiting strain P. aeruginosa 2apa can be used as an effective biological control candidate against devastating fungal and bacterial pathogens, which attack both root and foliar portions of tomato plant. Production of other functional traits such as IAA and siderophore may enhance its potential as biofertilizer. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. Report of the APA Task Force on the Sexualization of Girls

    Science.gov (United States)

    American Psychological Association (APA), 2007

    2007-01-01

    The American Psychological Association (APA) Task Force on the Sexualization of Girls was formed in response to expressions of public concern regarding the sexualization of girls and girlhood in U.S. culture. This report examines and summarizes psychological theory, research, and clinical experience addressing the sexualization of girls. The…

  8. seed storage proteins arl2 and its variants from the apa locus of wild ...

    African Journals Online (AJOL)

    sion of arcelin and ARL2 tepary bean proteins. Furthermore, a reduction in size and weight of emerged adult insects to almost half was observed. This work demonstrates the superior resistance common bean backcross lines to A. obtectus conferred by the presence of the APA proteins introgressed from tepary bean.

  9. APA's Learning Objectives for Research Methods and Statistics in Practice: A Multimethod Analysis

    Science.gov (United States)

    Tomcho, Thomas J.; Rice, Diana; Foels, Rob; Folmsbee, Leah; Vladescu, Jason; Lissman, Rachel; Matulewicz, Ryan; Bopp, Kara

    2009-01-01

    Research methods and statistics courses constitute a core undergraduate psychology requirement. We analyzed course syllabi and faculty self-reported coverage of both research methods and statistics course learning objectives to assess the concordance with APA's learning objectives (American Psychological Association, 2007). We obtained a sample of…

  10. Construction of doxycycline-mediated BMP-2 transgene combining with APA microcapsules for bone repair.

    Science.gov (United States)

    Qian, Dongyang; Bai, Bo; Yan, Guangbin; Zhang, Shujiang; Liu, Qi; Chen, Yi; Tan, Xiaobo; Zeng, Yanjun

    2016-01-01

    The repairing of large segmental bone defects is difficult for clinical orthopedists at present. Gene therapy is regarded as a promising method for bone defects repair. The present study aimed to construct an effective and controllable Tet-On expression system for transferring hBMP-2 gene into bone marrow mesenchymal progenitor cells (BMSCs). Meanwhile, with combination of alginate-poly-L-lysine-alginate (APA) microencapsulation technology, we attempted to reduce the influence of immunologic rejection and examine the effect of the Tet-On expression system on osteogenesis of BMSCs. The adenovirus encoding hBMP-2 (ADV-hBMP2) was constructed using the means of molecular cloning. The ADV-hBMP2 and Adeno-X Tet-On virus was respectively transfected to the HEK293 for amplification and afterward BMSCs were co-infected with the virus of ADV-hBMP2 and the Adeno-X Tet-On. The expression of hBMP-2 was measured with induction by doxycycline (DOX) at different concentration by means of RT-PCR and ELISA. Combining Tet-On expression system and APA microcapsules with the use of the pulsed high-voltage electrostatic microcapsule instrument, we examined the expression level of hBMP-2 in APA microcapsules by ELISA as well as the osteogenesis by alizarin red S staining. An effective Tet-On expression system for transferring hBMP-2 gene into BMSCs was constructed successfully. Also, the expression of hBMP-2 could be regulated by concentration of DOX. The data exhibited that BMSCs in APA microcapsules maintained the capability of proliferation and differentiation. The combination of Tet-On expression system and APA microcapsules could promote the osteogenesis of BMSCs. According to the results, microencapsulated Tet-On expression system showed the effective characteristics of secreting hBMP-2 and enhancing osteogenesis, which would provide a promising way for bone repair.

  11. Validity and reliability of an IMU-based method to detect APAs prior to gait initiation.

    Science.gov (United States)

    Mancini, Martina; Chiari, Lorenzo; Holmstrom, Lars; Salarian, Arash; Horak, Fay B

    2016-01-01

    Anticipatory postural adjustments (APAs) prior to gait initiation have been largely studied in traditional, laboratory settings using force plates under the feet to characterize the displacement of the center of pressure. However clinical trials and clinical practice would benefit from a portable, inexpensive method for characterizing APAs. Therefore, the main objectives of this study were (1) to develop a novel, automatic IMU-based method to detect and characterize APAs during gait initiation and (2) to measure its test-retest reliability. Experiment I was carried out in the laboratory to determine the validity of the IMU-based method in 10 subjects with PD (OFF medication) and 12 control subjects. Experiment II was carried out in the clinic, to determine test-retest reliability of the IMU-based method in a different set of 17 early-to-moderate, treated subjects with PD (tested ON medication) and 17 age-matched control subjects. Results showed that gait initiation characteristics (both APAs and 1st step) detected with our novel method were significantly correlated to the characteristics calculated with a force plate and motion analysis system. The size of APAs measured with either inertial sensors or force plate was significantly smaller in subjects with PD than in control subjects (p<0.05). Test-retest reliability for the gait initiation characteristics measured with inertial sensors was moderate-to-excellent (0.56

  12. APA/Psi Chi Edwin B. Newman Graduate Research Award: Meghan H. Puglia.

    Science.gov (United States)

    2016-11-01

    The Edwin B. Newman Graduate Research Award is given jointly by Psi Chi and APA. The award was established to recognize young researchers at the beginning of their professional lives and to commemorate both the 50th anniversary of Psi Chi and the 100th anniversary of psychology as a science (dating from the founding of Wundt's laboratory). The 2016 recipient is Meghan H. Puglia, who was chosen for "an outstanding foundational research paper that establishes a relationship between a functional epigenetic modification to the oxytocin receptor gene (OXTR) and neural response during social perception." Puglia's award citation, biography, and bibliography are presented here. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  13. Oscillatory transenantiomerization of the selected 2-arylpropionic acid (2-APAs) in vitro as a spontaneous phenomenon

    International Nuclear Information System (INIS)

    Sajewicz, M.; Alska, T.K.

    2006-01-01

    In this paper, we summarize the results of our earlier investigations on an attempted enantioseparation of the selected 2-arylpropionic acids (2-APAs) by means of the chiral thin layer chromatography (TLC). These results have been originally presented in a series of the research papers published in several chromatography journals. In the current article it was reminded that the prolonged storage of the investigated 2-APAs in the aqueous and the non-aqueous solutions results in an oscillatory change of the respective retardation factor (RF) and the specific rotation (alfa)/sub P/) values. An assumption is introduced as to the chemical nature of the observed phenomenon. It is assumed that the observed oscillations are due to the repeated structural inversion (in our study labelled as oscillatory transenantiomerization) of one enantiomer to its respective antimer. One attempts to at least roughly explain the molecular mechanism of transenantiomerization either by keto-enol tautomerism, or by formation of an intermediate enolic anion, any of these two reaction mechanisms possible only in the basic environment. Then one reflects on the most probable mechanism responsible for the oscillatory nature of the observed structural inversion. It is concluded that the oscillations could be due to an enhanced viscosity of the investigated 2-APA solutions (as compared with those of the respective pure solvents) and/or due to the molecular self-organization within these solutions, resulting in anisotropic properties thereof. Finally, it is concluded that an ultimate explanation of the observed oscillatory transenantiomerization of the selected 2-APAs could probably be offered by the Brusselator-type kinetic model implemented with the diffusion term. In the last section of this paper, argumentation is presented strongly in favour of this particular model and against any alternative speculation as to the supramolecular nature of the observed oscillatory phenomena. (author)

  14. APA Award for Distinguished Professional Contributions to Applied Research: Cameron J. Camp.

    Science.gov (United States)

    2017-12-01

    The Award for Distinguished Professional Contributions to Applied Research is given to a psychologist whose research has led to important discoveries or developments in the field of applied psychology. The 2017 recipient is Cameron J. Camp, whose innovative programs have informed psychologists in working with dementia patients to improve their living skills and enhance their independence. Camp's award citation, biography, and a selected bibliography are presented here. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  15. Grounding Hypnosis in Science: The 'New' APA Division 30 definition of hypnosis as a step backwards.

    OpenAIRE

    Lynn, Stephen Jay; Green, Joseph P.; Kirsch , Irving; Capafons, Antonio; Lilienfeld, .S.OScott O; Laurence, Jean R.; Montgomery, Guy H.

    2015-01-01

    Every decade or so, the Division 30 of the American Psychological Association (APA) has seen fit to redefine hypnosis (Elkins, Barabasz, Council, & Spiegel, 2015; Green, Barabasz, Barrett, & Montgomery, 2005; Kirsch, 1994). In the latest attempt, the Hypnosis Definition Committee (HDC) defined hypnosis as a 'state of consciousness involving focused attention and reduced peripheral awareness characterized by an enhanced capacity for response to suggestion' (Elkins et al., 2015, p. 6). One migh...

  16. Synthesis and properties of ApA analogues with shortened phosphonate internucleotide linkage

    Czech Academy of Sciences Publication Activity Database

    Králíková, Šárka; Buděšínský, Miloš; Barvík, I.; Masojídková, Milena; Točík, Zdeněk; Rosenberg, Ivan

    2011-01-01

    Roč. 30, 7/9 (2011), s. 524-543 ISSN 1525-7770 R&D Projects: GA ČR GA202/09/0193; GA AV ČR KAN200520801; GA MŠk(CZ) LC06061 Institutional research plan: CEZ:AV0Z40550506 Keywords : alpha-hydroxy-phosphonate linkage * ApA analogues * phosphonate internucleotide bond * NMR conformational study Subject RIV: CC - Organic Chemistry Impact factor: 0.899, year: 2011

  17. Evaluation of an Image Analysis Device (APAS) for Screening Urine Cultures.

    Science.gov (United States)

    Glasson, John; Hill, Rhys; Summerford, Michael; Giglio, Steven

    2016-02-01

    While advancements have been made in some areas of pathology with diagnostic materials being screened using image analysis technologies, the reporting of cultures from agar plates remains a manual process. We compared the results for 2,163 urine cultures read by a reference panel of microbiologists, by the routine laboratory process, and by an automated plate reading system, APAS (LBT Innovations Ltd., South Australia). APAS detected colonies with a sensitivity of 99.1% and a specificity of 99.3% on blood agar, while on MacConkey agar, the colony detection sensitivity was 99.4% with a specificity of 99.3%. The device's ability to enumerate growth had an accuracy of 89.2%, and the morphological identification of colonies showed a high level of performance for the colony types typical of Escherichia coli and other enteric bacilli. On blood agar, lactose-fermenting colonies were morphologically identified with a sensitivity of 98.9%, while on MacConkey agar they were identified with a sensitivity of 99.2%. In this first clinical evaluation, APAS demonstrated high performance in the detection, enumeration, and colony classification of isolates compared with that for conventional plate-reading methods. The device found all cases reported by the laboratory and detected the most commonly encountered organisms found in urinary tract infections. Copyright © 2016 Glasson et al.

  18. The effect of recombinant aminopeptidase A (APA) on hypertension in pregnant spontaneously hypertensive rats (SHRs).

    Science.gov (United States)

    Ishii, Masakazu; Hattori, Akira; Numaguchi, Yasushi; Ma, Xiuyang; Nagasaka, Tetsuro; Tsujimoto, Masafumi; Murohara, Toyoaki; Kobayashi, Hiroshi; Mizutani, Sigehiko

    2009-09-01

    We have tested the effects of aminopeptidase A (APA), MgSO(4) and various conventional antihypertensive drugs on hypertension in pregnant spontaneously hypertensive rats (SHRs) and examined the effects on both fetal heart and kidney. We used recombinant human APA, which has been recently shown to work as an antihypertensive agent in SHRs (n=5). Each drug was administered from gestational day 10 to day 20 and each dose was increased daily up to 10 fold until the end of treatment except for MgSO(4) (n=5 per each group). Blood pressure (BP) was monitored and fetal kidneys and heart were histologically examined. The antihypertensive effects of the drugs were in the following order: hydralazine>aminopeptidase A and angiotensin receptor blockers (ARBs), candesartan>MgSO(4) and methyldopa. Microscopic examination showed that fetal exposure to candesartan is associated with poor proximal tubular differentiation in the kidney and that to MgSO(4) is associated with poor blood vessel formation in the heart, respectively. Our present study showed that APA is one of the candidates for antihypertensive agents in hypertension during pregnancy.

  19. Cynthia J. Najdowski: Psi Chi/APA Edwin B. Newman Graduate Research Award.

    Science.gov (United States)

    2012-11-01

    Presents a short biography of the winner of the American Psychological Association's Psi Chi/APA Edwin B. Newman Graduate Research Award. The 2012 winner is Cynthia J. Najdowski for an outstanding research paper that examines how jurors' judgments are influenced by a juvenile defendant's confession and status as intellectually disabled. Through the use of a mock trial experiment, the research revealed that jurors discounted a juvenile's coerced confession and sometimes used intellectual disability as a mitigating factor. Attribution theory and the discounting principle were used to identify the psychological mechanisms underlying this effect. The paper, titled 'Understanding Jurors' Judgments in Cases Involving Juvenile Defendants,' was published in Psychology, Public Policy, and Law in October 2011 and was the basis for Najdowski's selection as the recipient of the 2012 Psi Chi/APA Edwin B. Newman Graduate Research Award. Bette L. Bottoms, PhD, served as faculty supervisor. Najdowski's Award citation and a selected bibliography are also presented. PsycINFO Database Record (c) 2012 APA, all rights reserved.

  20. IAP/APA evidence-based guidelines for the management of acute pancreatitis.

    Science.gov (United States)

    2013-01-01

    There have been substantial improvements in the management of acute pancreatitis since the publication of the International Association of Pancreatology (IAP) treatment guidelines in 2002. A collaboration of the IAP and the American Pancreatic Association (APA) was undertaken to revise these guidelines using an evidence-based approach. Twelve multidisciplinary review groups performed systematic literature reviews to answer 38 predefined clinical questions. Recommendations were graded using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. The review groups presented their recommendations during the 2012 joint IAP/APA meeting. At this one-day, interactive conference, relevant remarks were voiced and overall agreement on each recommendation was quantified using plenary voting. The 38 recommendations covered 12 topics related to the clinical management of acute pancreatitis: A) diagnosis of acute pancreatitis and etiology, B) prognostication/predicting severity, C) imaging, D) fluid therapy, E) intensive care management, F) preventing infectious complications, G) nutritional support, H) biliary tract management, I) indications for intervention in necrotizing pancreatitis, J) timing of intervention in necrotizing pancreatitis, K) intervention strategies in necrotizing pancreatitis, and L) timing of cholecystectomy. Using the GRADE system, 21 of the 38 (55%) recommendations, were rated as 'strong' and plenary voting revealed 'strong agreement' for 34 (89%) recommendations. The 2012 IAP/APA guidelines provide recommendations concerning key aspects of medical and surgical management of acute pancreatitis based on the currently available evidence. These recommendations should serve as a reference standard for current management and guide future clinical research on acute pancreatitis. Copyright © 2013 IAP and EPC. Published by Elsevier B.V. All rights reserved.

  1. cis-Apa: a practical linker for the microwave-assisted preparation of cyclic pseudopeptides via RCM cyclative cleavage.

    Science.gov (United States)

    Baron, Alice; Verdié, Pascal; Martinez, Jean; Lamaty, Frédéric

    2011-02-04

    A new linker cis-5-aminopent-3-enoic acid (cis-Apa) was prepared for the synthesis of cyclic pseudopeptides by cyclization-cleavage by using ring-closing methatesis (RCM). We developed a new synthetic pathway for the preparation of the cis-Apa linker that was tested in the cyclization-cleavage process of different RGD peptide sequences. Different macrocyclic peptidomimetics were prepared by using this integrated microwave-assisted method, showing that the readily available cis-Apa amino acid is well adapted as a linker in the cyclization-cleavage process.

  2. [Study on relationship of dose-effect and time-effect of APA microencapsulated bovine chromaffin cells on pain treatment].

    Science.gov (United States)

    Hui, Jianfeng; Li, Tao; Du, Zhi; Song, Jichang

    2011-12-01

    This study was to investigate the relationship of dose-effect and time-effect of Alginate-Polylysine-Alginate (APA) microencapsulated bovine chromaffin cells on the treatment of pain model rats. Using a rat model of painful peripheral neuropathy, the antinociceptive effects of APA microencapsulated bovine cells transplanted into the subarachnoid space was evaluated by cold allodynia test and hot hyperalgesia test. Compared with control group, the withdrawal difference with cell number 50 thousands groups, 100 thousands groups and 200 thousands groups was reduced (P APA microencapsulated bovine chromaffin cells which were transplanted to treat pain model rats, and the effective antinociception remained longer than 12 weeks.

  3. Complementing the Latest APA Definition of Hypnosis: Sensory-Motor and Vascular Peculiarities Involved in Hypnotizability.

    Science.gov (United States)

    Santarcangelo, Enrica L; Scattina, Eliana

    2016-01-01

    The aim of this article is to complement the recently revised American Psychological Association (APA) definition of hypnotizability. It (a) lists a few differences in sensorimotor integration between subjects with high (highs) and low (lows) hypnotizability scores in the ordinary state of consciousness and in the absence of suggestions, (b) proposes that hypnotizability-related cerebellar peculiarities may account for them, (c) suggests that the cerebellum could also be involved in cognitive aspects of hypnotizability and (d) explains why the information derived from studies of sensorimotor and cardiovascular aspects of hypnotizability may be relevant to its definition and useful in orienting further experimental research in the field of hypnosis.

  4. APA/Psi Chi Edwin B. Newman Graduate Research Award: Samantha F. Anderson.

    Science.gov (United States)

    2017-12-01

    The Edwin B. Newman Graduate Research Award is given jointly by Psi Chi and the American Psychological Association. The award was established to recognize young researchers at the beginning of their professional lives and to commemorate both the 50th anniversary of Psi Chi and the 100th anniversary of psychology as a science (dating from the founding of Wundt's laboratory). The 2017 recipient is Samantha F. Anderson, who was chosen for "an exceptional research paper that responds to psychology's 'replication crisis' by outlining a broader view of success in replication." Her award citation, biography, and a selected bibliography are presented here. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  5. Advanced plutonium assembly (apa): evolution of the concept, neutron and thermal-mechanic constraints

    International Nuclear Information System (INIS)

    Porta, J.; Gastaldi, B.; Krakowiak-Aillaud, C.; Buffe, L.

    2002-01-01

    The APA concept was developed with the aim of increasing the PWR capacity to burn plutonium emerging from the recycling of irradiated fuels in the French park of nuclear power plants. At first, a concept using annular pins was optimised to allow a good consumption of plutonium while preserving an acceptable neutron control. To cope with the technological problems and those posed by the manufacture of these annular pins, an alternative concept is presented here. It poses as initial conditions the conservation of both the plutonium balance and the respect of the reactivity control. (authors)

  6. Manual of References, Creating Tables and Figures in Scholarly Publications: APA 6 Rules

    Directory of Open Access Journals (Sweden)

    Mehmet Ali Akkaya

    2016-12-01

    Full Text Available One precondition of contribution of a discipline to its field, to the scientific word in general and to the entire humankind is producing qualified scientific publications in the related field or discipline. National and international standard(s provided for citing and referencing tables and figures, in addition to the content (and context of the scientific publications might provide the relevant publication to be more widely and correctly read and reviewed. This study deals with adaptation of the latest edition of the American Psychological Association (APA rules. This book, where the APA rules -already a universal authority in citing and referencing- are enriched with specific examples for every type of information source, is a basic reference source after Prof. Dr. S. Kurbanoğlu’s “Kaynak Gösterme El Kitabı” (Referencing Handbook in 2004 that can be implemented not only to the Information and Records Management field, but to the whole scientific world. The meaning and importance of the work of Şencan and Doğan, is much more profound in our country where along with the quality of the scientific publications, the stylistic compatibility with the scientific criteria is also very often questioned.

  7. Sümeyra Tosun: Psi Chi/APA Edwin B. Newman Graduate Research Award.

    Science.gov (United States)

    2014-11-01

    The Edwin B. Newman Graduate Research Award is given jointly by Psi Chi and APA. The award was established to recognize young researchers at the beginning of their professional lives and to commemorate both the 50th anniversary of Psi Chi and the 100th anniversary of psychology as a science (dating from the founding of Wundt's laboratory). The 2014 recipient is Sümeyra Tosun. Tosun was chosen for "an outstanding research paper that examines the cognitive repercussions of obligatory versus optional marking of evidentiality, the linguistic coding of the source of information. In English, evidentiality is conveyed in the lexicon through the use of adverbs. In Turkish, evidentiality is coded in the grammar. In two experiments, it was found that English speakers were equally good at remembering and monitoring the source of firsthand information and the source of non-firsthand information. Turkish speakers were worse at remembering and monitoring non-firsthand information than firsthand information and were worse than English speakers at remembering and monitoring non-firsthand information." Tosun's award citation, biography, and a selected bibliography are presented here. PsycINFO Database Record (c) 2014 APA, all rights reserved.

  8. Linking contemporary research to the classics: Celebrating 125 years at APA.

    Science.gov (United States)

    Enns, James T; Becker, Stefanie I; Brockmole, James; Castelhano, Monica; Creem-Regehr, Sarah; Gray, Rob; Hecht, Heiko; Juhasz, Barbara; Philbeck, John; Woodman, Geoffrey

    2017-10-01

    APA is celebrating 125 years this year and at the journal we are commemorating this milestone with a special issue. The inspiration came from our editorial team, who wished to acknowledge the links between game-changing articles that have influenced our research community in the past-we call them classics for short-and contemporary works. The main idea was to feature the work of nine contemporary research teams, while at the same time drawing readers' attention to their links with the classics. In this introduction, we have organized the articles according to several broad themes: active perception, perception for action, action alters perception, perception of our bodies in action, and acting on selective perceptions. As all who have read and contributed to the journal over the past few years have come to realize, it is no longer possible to study perception without considering its role in action. Nor is it possible to study action (formerly called performance , as reflected in the journal title) without understanding the perceptual contributions to action. These nine articles each exemplify, in their own way, how these dynamic interactions play out in contemporary research in our field. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  9. Journal article reporting standards for quantitative research in psychology: The APA Publications and Communications Board task force report.

    Science.gov (United States)

    Appelbaum, Mark; Cooper, Harris; Kline, Rex B; Mayo-Wilson, Evan; Nezu, Arthur M; Rao, Stephen M

    2018-01-01

    Following a review of extant reporting standards for scientific publication, and reviewing 10 years of experience since publication of the first set of reporting standards by the American Psychological Association (APA; APA Publications and Communications Board Working Group on Journal Article Reporting Standards, 2008), the APA Working Group on Quantitative Research Reporting Standards recommended some modifications to the original standards. Examples of modifications include division of hypotheses, analyses, and conclusions into 3 groupings (primary, secondary, and exploratory) and some changes to the section on meta-analysis. Several new modules are included that report standards for observational studies, clinical trials, longitudinal studies, replication studies, and N-of-1 studies. In addition, standards for analytic methods with unique characteristics and output (structural equation modeling and Bayesian analysis) are included. These proposals were accepted by the Publications and Communications Board of APA and supersede the standards included in the 6th edition of the Publication Manual of the American Psychological Association (APA, 2010). (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  10. Techniques for heating eccentrically located tumors with the BSD annular phased array system (APAS): Clinical experience

    International Nuclear Information System (INIS)

    Samulski, T.V.; Kapp, D.S.; Bagshaw, M.A.; Fessenden, P.; Lee, E.R.; Lohrbach, A.W.

    1985-01-01

    The authors are currently investigating the potential for treatment optimization with the BSD APAS in tumors which are eccentrically located within the lower abdomen and pelvis. Attempts have been made to manipulate electric field (E-field) distribution during treatments through frequency changes and partial array activation (driving less than all four quadrants). Field shifts are qualitatively documented using the manufacturer's supplied diode array probes located at the patient/bolus interface in anterior, posterior and bilateral positions. Preliminary findings indicate that the internal E-field distributions can be manipulated to result in better treatment tolerance and better temperature distributions in selected target volumes. Phantom and clinical data are presented demonstrating the utility of these approaches

  11. The family Passifloraceae in APA Serra Branca/Raso da Catarina, Jeremoabo, Bahia, Brazil

    Directory of Open Access Journals (Sweden)

    Jéssica Vieira dos Santos

    2016-02-01

    Full Text Available This work presents a floristic survey of the family Passifloraceae in APA Serra Branca/Raso da Catarina, located in the municipality of Jeremoabo, Bahia. The family has a pantropical distribution and includes about 20 genera and 600 species. In Brazil there are four genera, Ancistrothyrsus, Dilkea, Mitostemma and Passiflora, the latter being the most diverse. In the Caatinga biome there are 29 species, including one species of Mitostemma and the others of Passiflora. The samples analyzed were collected from August/2011 to February/2013, and the analyses were supplemented with dried collections kept in the following herbaria: ALCB, HRB and HUEFS. Four species of the genus Passiflora were recorded: Passiflora cincinnata, P. foetida, P. luetzelburgii and P. setacea. Comments about the morphology and taxonomy, data on geographical distribution and phenology, illustrations, and a key to the taxa studied are provided.

  12. APA-style human milk fat analogue from silkworm pupae oil: Enzymatic production and improving storage stability using alkyl caffeates.

    Science.gov (United States)

    Liu, Xi; Wang, Xudong; Pang, Na; Zhu, Weijie; Zhao, Xingyu; Wang, Fangqin; Wu, Fuan; Wang, Jun

    2015-12-08

    Silkworm pupae oil derived from reeling waste is a rich source of α-linolenic acid (ALA), which has multipal applications. ALAs were added in sn-1, 3 positions in a triacylglycerol (TAG) to produce an APA-human milk fat analogues (APA-HMFAs, A: α-linolenic acid, P: palmitic acid). The optimum condition is that tripalmitin to free fatty acids of 1:12 (mole ratio) at 65 °C for 48 h using lipase Lipozyme RM IM. Results show that, the major TAG species that comprised APA-HMFAs were rich in ALA and palmitic acid, which contained 64.52% total unsaturated fatty acids (UFAs) and 97.05% PA at the sn-2 position. The melting point of APA was -27.5 °C which is much lower than tripalmitin (40.5 °C) indicating more plastic character. In addition, the practical application of alkyl caffeates as liposoluble antioxidants in APA was developed. Alkyl caffeate showed a superior IC50 (1.25-1.66 μg/mL) compared to butyl hydroxy anisd (1.67 μg/mL) and L-ascorbic acid-6-palmitate (L-AP) (1.87 μg/mL) in DPPH analysis. The addition of ethyl caffeate to oil achieved a higher UFAs content (73.58%) at high temperatures. Overall, APA was obtained from silkworm pupae oil successfully, and the addition of caffeates extended storage ranges for APA-HMFAs.

  13. Role of the VDR Bsm I and Apa I polymorphisms in the risk of colorectal cancer in Kashmir.

    Science.gov (United States)

    Rasool, Sabha; Kadla, Showkat A; Rasool, Vamiq; Qazi, Falak; Khan, Tanzeela; Shah, Nisar A; Ganai, Bashir A

    2014-01-01

    A case-control study aiming to evaluate the relationship between Bsm I and Apa I restriction fragment gene polymorphisms and colorectal cancer (CRC) was carried out in Kashmir, including a total of 368 subjects (180 cases and 188 controls). DNA samples extracted from the blood of the subjects were analyzed for 3' untranslated region (3' UTR) Apa I and Bsm I polymorphisms using restriction fragment length polymorphism-polymerase chain reaction (RFLP-PCR). A statistically significant 2.7-fold increased risk was observed in individuals found homozygous for the presence of the 'b' allele, in comparison to subjects homozygous for the 'B' allele (odds ratio (OR) 2.7, 95% confidence interval (CI) 1.49-4.86 (Bsm I)), and a statistically insignificant 2-fold increased risk was found among individuals with the 'aa' genotype, as compared to subjects with the 'AA' genotype (OR 2.017, 95% CI 0.86-4.7). Our study also yielded statistically significant results when the Apa I polymorphism was stratified by age (≤ 50 years) and dwelling area (rural area), and the Bsm I polymorphism by gender (male gender), suggesting a possible role of Apa I and Bsm I polymorphisms in the etiology of CRC in Kashmir. We conclude that Apa I and Bsm I single-nucleotide polymorphisms (SNPs) in the vitamin D receptor gene (VDR) might be associated with susceptibility to CRC among Kashmiris. © 2014 S. Karger GmbH, Freiburg.

  14. IL-1RA gene-transfected bone marrow-derived mesenchymal stem cells in APA microcapsules could alleviate rheumatoid arthritis.

    Science.gov (United States)

    Hu, Jianhua; Li, Hongjian; Chi, Guanhao; Yang, Zhao; Zhao, Yi; Liu, Wei; Zhang, Chao

    2015-01-01

    In order to investigate the encapsulation of interleukin 1 receptor antagonist (IL-RA) gene-modified mesenchymal stem cells (MSCs) in alginate-poly-L-lysine (APA) microcapsules for the persistent delivery of interleukin 1 receptor antagonist (IL-RA) to treat Rheumatoid arthritis (RA). We transfect mesenchymal stem cells with IL-RA gene, and quantify the IL-RA proteins released from the encapsulated cells followed by microencapsulation of recombinant mesenchymal stem cells, and thus observe the permeability of APA microcapsules and evaluate clinical effects after induction and treatment of collagen-induced arthritis (CIA). The concentration of IL-RA in the supernatant was determined by IL-RA ELISA kit by run in technical triplicates using samples from three separate mice. Encapsulated IL-RA gene-transfected cells were capable of constitutive delivery of IL-RA proteins for at least 30 days. Moreover, the APA microcapsules could inhibit the permeation of fluorescein isothiocyanate-conjuncted immunoglobulin G. Also, it has been found that the APA microcapsules can significantly attenuate collagen induced arthritis after delivering of APA microcapsules to rats. Our results demonstrated that the nonautologous IL-RA gene-transfected stem cells are of potential utility for RA therapy.

  15. Unidades de conservação, Legislação ambiental e a APA Petrópolis

    Directory of Open Access Journals (Sweden)

    Julieta Laudelina de Paiva

    2010-12-01

    Full Text Available As unidades de conservação são criadas com o objetivo de manter a diversidade biológica, proteger espécies ameaçadas de extinção, preservar e restaurar ecossistemas naturais. A Área de Proteção Ambiental da Região Serrana de Petrópolis – APA PETRÓPOLIS, primeira APA federal, foi criada por apresentar rica biodiversidade além de ter seus atributos naturais relativamente bem conservados. A população residente na APA Petrópolis está submetida ao cumprimento de várias determinações legais nos três níveis administrativos.

  16. The affection of APA microcapsulation on catecholamine and leucine-enkephalin secretion from the bovine adrenal medullary chromaffin cells

    International Nuclear Information System (INIS)

    Guo Shuilong; Cui Xin; Luo Yun; Xue Yilong

    2002-01-01

    The affection of alginate-polylysine-alginate (APA) microcapsulation on catecholamine (CA) and leucine-enkephalin (L-EK) secretion from bovine adrenal medullary chromaffin cells was analysed. Encapsulating BCCs with the APA microcapsulation, the secretion of CA and L-EK in encapsulated BCCs was detected by high-performance liquid chromatography-electrochemical assay and radioimmunoassay, respectively. There is little difference between the encapsulated BCCs and the non-encapsulated BCCs in the secretion of epinephrine (E) and noradrenaline (NE) but the secretion of dopamine (DA) and L-EK in several points decline. The studies indicated that APA microcapsulation of BCCs didn't affect the secretion of E and NE, but did the secretion DA and L-EK in forepart

  17. The Neuro-Mechanical Processes That Underlie Goal-Directed Medio-Lateral APA during Gait Initiation.

    Science.gov (United States)

    Honeine, Jean-Louis; Schieppati, Marco; Crisafulli, Oscar; Do, Manh-Cuong

    2016-01-01

    Gait initiation (GI) involves passing from bipedal to unipedal stance. It requires a rapid movement of the center of foot pressure (CoP) towards the future swing foot and of the center of mass (CoM) in the direction of the stance foot prior to the incoming step. This anticipatory postural adjustment (APA) allows disengaging the swing leg from the ground and establishing favorable conditions for stepping. This study aimed to describe the neuro-mechanical process that underlies the goal-directed medio-lateral (ML) APA. We hypothesized that controlled knee flexion of the stance leg contributes to the initial ML displacement of the CoP and to the calibration of the first step. Fourteen subjects initiated gait starting from three different initial stance widths of 15 cm (Small), 30 cm (Medium), and 45 cm (Large). Optoelectronic, force platform and electromyogram (EMG) measurements were performed. During APA, soleus activity diminished bilaterally, while tibialis anterior (TA) activity increased, more so in the stance leg than in the swing leg, and to a larger extent with increasing initial stance width. Knee flexion of the stance leg was observed during APA and correlated with the ML CoP displacement towards the swing leg. ML CoP and CoM displacements during APA increased with increasing stance width. The activity of stance-leg TA was correlated with the degree of knee flexion. Swing-leg tensor fasciae latae (TFL) was also active during APA. Across subjects, when stance-leg tibialis activity was low, TFL activity was large and vice versa. The modulation of the ML CoP position during APA allowed the gravity-driven torque to place the CoM just lateral to the stance foot during step execution. Accordingly, the gravity-driven torque, the ML CoM velocity during step execution, and the step width at foot contact (FC) were lower in the Small and greater in the Large condition. Consequently, the position of the stepping foot at FC remained close to the sagittal plane in all

  18. Synthesis and properties of ApA analogues with shortened phosphonate internucleotide linkage.

    Science.gov (United States)

    Králíková, Sárka; Buděšínský, Miloš; Barvík, Ivan; Masojídková, Milena; Točík, Zdeněk; Rosenberg, Ivan

    2011-01-01

    A complete series of the 2 '-5 ' and 3 '-5 ' regioisomeric types of r(ApA) and 2 '-d(ApA) analogues with the α-hydroxy-phosphonate C3 '-O-P-CH(OH)-C4 ″ internucleotide linkage, isopolar but non-isosteric with the phosphodiester one, were synthesized and their hybridization properties with polyU studied. Due to the chirality on the 5 '-carbon atom of the modified internucleotide linkage bearing phosphorus and hydroxy moieties, each regioisomeric type of ApA dimer is split into epimeric pairs. To examine the role of the 5 '-hydroxyl of the α-hydroxy-phosphonate moiety during hybridization, the appropriate r(ApA) analogues with 3 '(2 ')-O-P-CH(2)-C4 ″ linkage lacking the 5 '-hydroxyl were synthesized. Nuclear magnetic resonance (NMR) spectroscopy study on the conformation of the modified sugar-phosphate backbone, along with the hybridization measurements, revealed remarkable differences in the stability of complexes with polyU, depending on the 5 '-carbon atom configuration. Potential usefulness of the α-hydroxy-phosphonate linkage in modified oligoribonucleotides is discussed.

  19. APA guidelines: their importance and a plan to keep them current: 2013 annual report of the Policy and Planning Board.

    Science.gov (United States)

    2014-01-01

    When guidelines are approved by APA, they become association policy, and it is imperative that they remain current. The revision of guidelines poses several challenges to the association. These challenges range from the availability and allocation of resources to support the complicated processes involved in developing and updating these policies to the lack of a clearly defined process that includes identification of tasks, assignments of responsibilities, and so forth. For this reason, the APA Board of Directors asked the Policy and Planning Board (P&P) to work with the boards of the four directorates (i.e., the Education Directorate, the Practice Directorate, the Public Interest Directorate, and the Science Directorate) to create a proposal that would (a) make recommendations with regard to how the review and revision of guidelines documents might best be accomplished in accordance with the APA Strategic Plan and existing policies and procedures and (b) make suggestions regarding the association resources that might be required. The Board of Directors approved the proposed review process in December 2013. 2014 APA, all rights reserved

  20. A Reliable and Valid Weighted Scoring Instrument for Use in Grading APA-Style Empirical Research Report

    Science.gov (United States)

    Greenberg, Kathleen Puglisi

    2012-01-01

    The scoring instrument described in this article is based on a deconstruction of the seven sections of an American Psychological Association (APA)-style empirical research report into a set of learning outcomes divided into content-, expression-, and format-related categories. A double-weighting scheme used to score the report yields a final grade…

  1. Association of Taq I, Fok I and Apa I polymorphisms in Vitamin D Receptor (VDR) gene with leprosy.

    Science.gov (United States)

    Neela, Venkata Sanjeev Kumar; Suryadevara, Naveen Chandra; Shinde, Vidya Gouri; Pydi, Satya Sudheer; Jain, Suman; Jonnalagada, Subbanna; Singh, Surya Satyanarayana; Valluri, Vijaya Lakshmi; Anandaraj, M P J S

    2015-06-01

    Vitamin D Receptor (VDR) is a transacting transcription factor which mediates immunomodulatory function and plays a key role in innate and adaptive immune responses through its ligand and polymorphisms in VDR gene may affect its regulatory function. To investigate the association of three VDR gene polymorphisms (TaqI rs731236, FokI rs2228570 and ApaI rs7975232) with leprosy. The study group includes 404 participants of which 222 were leprosy patients (paucibacillary=87, multibacillary=135) and 182 healthy controls. Genotyping was done using PCR-RFLP technique. Statistical analysis was performed using SNP Stats and PLINK software. The VDR FokI (rs2228570) ff genotype, ApaI (rs7975232) AA, Aa genotype and haplotype T-f-a, T-F-A were positively associated with leprosy when compared to healthy controls. The two variants at Fok and Apa positions in VDR gene are significantly associated with leprosy. Genotypes at FokI (ff), ApaI (aa) and haplotype (T-F-a, T-f-a) may contribute to the risk of developing leprosy by altering VDR phenotype/levels subsequently modulation of immune response. Copyright © 2015 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.

  2. Advocating for School Psychologists in Response to the APA's Proposed "Model Act for State Licensure of Psychologists"

    Science.gov (United States)

    Skalski, Anastasia Kalamaros

    2009-01-01

    On March 6, 2009, the APA Model Licensure Act Task Force released its second draft of the policy document known as the proposed "Model Act for State Licensure of Psychologists". This policy document serves as guidance to state legislatures for how they should set up their psychology licensing laws. The general expectations promoted in the model…

  3. Changes in the APA "Publication Manual": How the New Fifth Edition Will Affect Research Reporting in the Social Sciences.

    Science.gov (United States)

    Daniel, Larry G.

    The American Psychological Association (APA) has recently published the fifth edition of its "Publication Manual." This paper provides a brief overview of how this edition differs from previous editions and summarizes features of the new edition that will be likely to have an impact on social science research over the next several years.…

  4. PLANEJAMENTO DE UMA TRILHA INTERPRETATIVA COMO FERRAMENTA DO ECOTURISMO NA APA DA BARRA DO RIO MAMANGUAPE - PARAÍBA, BRASIL

    Directory of Open Access Journals (Sweden)

    Mércia Maria Araújo Luna

    2016-04-01

    Full Text Available A Floresta Atlântica é um bioma biodiverso e extremamente impactado. A Área de Proteção Ambiental (APA da Barra do Rio Mamanguape encontra-se inserida no hotspot da Floresta Atlântica. Este trabalho visa propor a implantação de uma trilha interpretativa na APA com base no Ecoturismo e na Educação Ambiental. Durante o mês de abril e maio de 2014 foi elaborado um roteiro mapeando os pontos estratégicos da trilha, elencando seus elementos mais representativos e registrando-os ao longo de 3.8 Km. Várias características da trilha foram consideradas na elaboração deste planejamento: a proteção do ambiente da trilha, seu potencial interpretativo, a acessibilidade e segurança. Os resultados apontaram nove pontos de atratividade onde foram abordados aspectos de relevância da flora, da fauna e da história da APA. Nota-se a necessidade da implantação de trilhas ecológicas no principal e maior fragmento de Floresta Atântica da APA, a Floresta do Oiteiro, uma vez que as trilhas só estão previstas no plano de manejo para um dos quatro municípios que abrange a APA, Lucena. Destaque pode ser dado à necessidade de treinamento de uma equipe local da Unidade de Conservação (UC para manter vivo o instrumento da trilha interpretativa, associando a interlocução entre a comunidade acadêmica da UFPB e os turistas pelo seu caráter amplo e interdisciplinar. Palavras-chave: Floresta Atlântica. Unidades de conservação. Turismo ecológico.

  5. Multicenter Evaluation of an Image Analysis Device (APAS): Comparison Between Digital Image and Traditional Plate Reading Using Urine Cultures.

    Science.gov (United States)

    Glasson, John; Hill, Rhys; Summerford, Michael; Olden, Dianne; Papadopoulos, Fotula; Young, Stephen; Giglio, Steven

    2017-11-01

    The application of image analysis technologies for the interpretation of microbiological cultures is evolving rapidly. The primary aim of this study was to establish whether the image analysis system named Automated Plate Assessment System (APAS; LBT Innovations Ltd., Australia) could be applied to screen urine cultures. A secondary aim was to evaluate differences between traditional plate reading (TPR) and the reading of cultures from images, or digital plate reading (DPR). A total of 9,224 urine samples submitted for culture to three clinical laboratories, two in Australia and one in the USA, were included in the study. Cultures were prepared on sheep blood and MacConkey agar plates and read by panels of three microbiologists. The plates were then presented to APAS for image capture and analysis, and the images and results were stored for later review. Image analysis of cultures using APAS produced a diagnostic sensitivity and specificity of 99.0% and 84.5%, respectively. Colonies were detected by APAS on 99.0% of blood agar plates with growth and on 99.5% of MacConkey agar plates. DPR agreed with TPR for colony enumeration on 92.1% of the plates, with a sensitivity of 90.8% and specificity of 92.8% for case designation. However, several differences in the classification of colony morphologies using DPR were identified. APAS was shown to be a reliable screening system for urine cultures. The study also showed acceptable concordance between DPR and TPR for colony detection, enumeration, and case designation. © The Korean Society for Laboratory Medicine

  6. Carbonatites and primary carbonates in the Rio Apa and Amambay regions, NE Paraguay

    Science.gov (United States)

    Comin-Chiaramonti, Piero; De Min, Angelo; Girardi, Vicente A. V.; Gomes, Celso B.

    2014-02-01

    In the Rio Apa and Amambay regions, north-eastern Paraguay (NPAA), potassic, alkaline-carbonatitic rocks (138-139 Ma) predate the eruption of tholeiitic flood basalts (133 ± 1 Ma). These rocks, mainly outcropping as dykes or ring-like complexes, intrude a Cambro-Ordovician carbonate platform and Precambrian metamorphic rocks along with their Silurian and Permo-Carboniferous sediments. The main rock-types range from basanite to trachyte and trachyphonolite (and intrusive equivalents) to carbonatite, in addition to glimmeritic and pyroxenitic veins. Geological and geophysical evidence indicate that the NPAA magmatism is related to extensional tectonics, like the Early Cretaceous alkaline-carbonatitic complexes from central-eastern Paraguay (127 ± 1 Ma) and the eastern magmatic occurrences of the Paraná Basin. Oxygen and carbon isotope compositions (whole rocks and carbonates) vary from values close to the field of continental lithospheric mantle, or that of primary carbonatites, up to values typical of a hydrothermal environment. An isotope exchange model implies that the main isotope variations, ranging from a magmatic (e.g., 1200 °C) to a low temperature (< 400 °C) environment, involved fluids with CO2/H2O ratios between 0.8 and 1.0. In particular, the Osbnd C isotopic variations, in combination with the La vs La/Yb ratios, suggest an increasingly higher level of carbonate in the silicate liquids, with increasing evolution, i.e., basanite → phonotephrite → trachyphonolite-phonolite (trachyte) → carbonatite. Srsbnd Nd isotopes show that the carbonatites are mantle derived without significant crustal contamination and that they can be related to isotopically enriched sources where newly formed veins (enriched component) and peridotite matrix (depleted component) underwent differing isotopic evolution. TDM model ages for NPAA range from 1.2 to 2.3 Ga. Considering that in the whole Paraná Basin isotopically distinct K-alkaline and tholeiitic magmas were

  7. Characterization of the Apa antigen from M. avium subsp. paratuberculosis: a conserved Mycobacterium antigen that elicits a strong humoral response in cattle.

    Science.gov (United States)

    Gioffré, A; Echeverría-Valencia, G; Arese, A; Morsella, C; Garbaccio, S; Delgado, F; Zumárraga, M; Paolicchi, F; Cataldi, A; Romano, M I

    2009-12-15

    Johne's disease or paratuberculosis is widespread in almost all countries and remains difficult to eradicate. Nowadays, diagnosis of Mycobacterium avium subsp. paratuberculosis (MPTB) infection is one of the main concerns. In this work, we evaluated the expression, biochemical properties and antigenicity of the Apa antigen, encoded by the gene annotated as MAP1569, in the MPTB genome. We confirmed its expression in MPTB and its glycosylation by the ConA binding assay. Although the MPTB-Apa is not an immunodominant antigen, MPTB-infected cattle showed a strong humoral response to recombinant Apa by Western blot and ELISA. Milk was also a suitable sample to be tested by ELISA. We comparatively analysed the humoral cross-reactivity to the Apa from MPTB (MPTB-Apa) and the orthologue from Mycobacterium tuberculosis (MT-Apa, identical to that from Mycobacterium bovis) in both infected and control cows. Response of M. bovis- and MPTB-infected animals against MT-Apa was similar (P=0.6985) but the response of the M. bovis-infected ones to MPTB-Apa was differential, being significantly diminished (PApa stimulation in the IFNgamma release assay, we found no significant differences when compared infected herds with non-infected ones (P=0.34). This antigen, in contrast to bovine Purified Protein Derivative (PPDb), was strongly represented in avian PPD (PPDa), as shown by the recognition of BALB/c mice hyperimmune sera against MPTB-Apa by Dot-blot immunoassay. We therefore demonstrated the antigenicity of Apa in MPTB-infected animals and a differential response to the recombinant antigen when compared to M. bovis-infected animals. These traits herein described, added to the usefulness of milk samples to detect IgG anti-Apa, could be important for routine screening in dairy cattle, considering a multiantigenic approach to overcome the lack of immunodominance.

  8. Selling violent video game solutions: A look inside the APA's internal notes leading to the creation of the APA's 2005 resolution on violence in video games and interactive media.

    Science.gov (United States)

    Copenhaver, Allen; Ferguson, Christopher J

    For decades politicians, parent groups, researchers, media outlets, professionals in various fields, and laymen have debated the effects playing violent video games have on children and adolescents. In academia, there also exists a divide as to whether violent video games cause children and adolescents to be aggressive, violent, and even engage in criminal behavior. Given inconsistencies in the data, it may be important to understand the ways and the reasons why professional organizations take a stance on the violent video game effects debate which may reflect greater expressed certitude than data can support. This piece focuses on the American Psychological Association's internal communications leading to the creation of their 2005 Resolution on Violence in Video Games and Interactive Media. These communications reveal that in this case, the APA attempted to "sell" itself as a solution to the perceived violent video game problem. The actions leading to the 2005 resolution are then compared to the actions of the APA's 2013-2015 Task Force on Violent Media. The implications and problems associated with the APA's actions regarding violent video games are addressed and discussed below. Copyright © 2018 Elsevier Ltd. All rights reserved.

  9. A Proposal for Six Sigma Integration for Large-Scale Production of Penicillin G and Subsequent Conversion to 6-APA.

    Science.gov (United States)

    Nandi, Anirban; Pan, Sharadwata; Potumarthi, Ravichandra; Danquah, Michael K; Sarethy, Indira P

    2014-01-01

    Six Sigma methodology has been successfully applied to daily operations by several leading global private firms including GE and Motorola, to leverage their net profits. Comparatively, limited studies have been conducted to find out whether this highly successful methodology can be applied to research and development (R&D). In the current study, we have reviewed and proposed a process for a probable integration of Six Sigma methodology to large-scale production of Penicillin G and its subsequent conversion to 6-aminopenicillanic acid (6-APA). It is anticipated that the important aspects of quality control and quality assurance will highly benefit from the integration of Six Sigma methodology in mass production of Penicillin G and/or its conversion to 6-APA.

  10. The science of ethics: Deception, the resilient self, and the APA code of ethics, 1966-1973.

    Science.gov (United States)

    Stark, Laura

    2010-01-01

    This paper has two aims. The first is to shed light on a remarkable archival source, namely survey responses from thousands of American psychologists during the 1960s in which they described their contemporary research practices and discussed whether the practices were "ethical." The second aim is to examine the process through which the American Psychological Association (APA) used these survey responses to create principles on how psychologists should treat human subjects. The paper focuses on debates over whether "deception" research was acceptable. It documents how members of the committee that wrote the principles refereed what was, in fact, a disagreement between two contemporary research orientations. The paper argues that the ethics committee ultimately built the model of "the resilient self" into the APA's 1973 ethics code. At the broadest level, the paper explores how prevailing understandings of human nature are written into seemingly universal and timeless codes of ethics. © 2010 Wiley Periodicals, Inc.

  11. "Bad girls rule": an interdisciplinary feminist commentary on the report of the APA Task Force on the Sexualization of Girls.

    Science.gov (United States)

    Lerum, Kari; Dworkin, Shari L

    2009-01-01

    Feminist, critical, and postmodern scholars have long recognized sexuality as a site of power relations. The recently released Report of the APA (American Psychological Association) Task Force on the Sexualization of Girls is a welcome addition to ongoing feminist and activist conversations on how to intervene on issues of sexuality in the name of girls' and women's health. This article offers a critical interdisciplinary analysis of this influential APA report, expanding on and challenging several of its main claims. This article critiques the report as over-determining the negative impact of sexualization; offers other literatures as critical additions including feminist literature on media, consumer culture, gender, and the body, and earlier "pro-desire" feminist psychology scholarship; and critiques the task force's conflations of objectification and sexualization. The article concludes with a call for broadening feminist scholarship and activism across disciplinary boundaries to emphasize girls' and women's sexual agency and resistance, as well as sexual health and rights.

  12. Race, Ethnicity, and Gender of Faculty Members in APA- and CACREP-Accredited Programs: Changes over Five Decades

    Science.gov (United States)

    Baggerly, Jennifer; Tan, Tony Xing; Pichotta, David; Warner, Aisha

    2017-01-01

    This study examined changes in race, ethnicity, and gender of faculty members in APA- and CACREP-accredited counseling programs over 5 decades based on the year of their degree. Of those faculty members working in accredited programs who graduated in the 1960s/1970s, 26.7% were female, 5.6% were racially diverse, and 1.7% were Latina/o. Of those…

  13. Are Adolescents Less Mature than Adults?: Minors' Access to Abortion, the Juvenile Death Penalty, and the Alleged APA "Flip-Flop"

    Science.gov (United States)

    Steinberg, Laurence; Cauffman, Elizabeth; Woolard, Jennifer; Graham, Sandra; Banich, Marie

    2009-01-01

    The American Psychological Association's (APA's) stance on the psychological maturity of adolescents has been criticized as inconsistent. In its Supreme Court amicus brief in "Roper v. Simmons" (2005), which abolished the juvenile death penalty, APA described adolescents as developmentally immature. In its amicus brief in "Hodgson v. Minnesota"…

  14. Putative alternative polyadenylation (APA) events in the early interaction of Salmonella enterica Typhimurium and human host cells.

    Science.gov (United States)

    Afonso-Grunz, Fabian

    2015-12-01

    The immune response of epithelial cells upon infection is mediated by changing activity levels of a variety of proteins along with changes in mRNA, and also ncRNA abundance. Alternative polyadenylation (APA) represents a mechanism that diversifies gene expression similar to alternative splicing. T-cell activation, neuronal activity, development and several human diseases including viral infections involve APA, but at present it remains unclear if this mechanism is also implicated in the response to bacterial infections. Our recently published study of interacting Salmonella enterica Typhimurium and human host cells includes genome-wide expression profiles of human epithelial cells prior and subsequent to infection with the invasive pathogen. The generated dataset (GEO accession number: GSE61730) covers several points of time post infection, and one of these interaction stages was additionally profiled with MACE-based dual 3'Seq, which allows for identification of polyadenylation (PA) sites. The present study features the polyadenylation landscape in early interacting cells based on this data, and provides a comparison of the identified PA sites with those of a corresponding 3P-Seq dataset of non-interacting cells. Differential PA site usage of FTL , PRDX1 and VAPA results in transcription of mRNA isoforms with distinct sets of miRNA and protein binding sites that influence processing, localization, stability, and translation of the respective mRNA. APA of these candidate genes consequently harbors the potential to modulate the host cell response to bacterial infection.

  15. Probiotic Ferulic Acid Esterase Active Lactobacillus fermentum NCIMB 5221 APA Microcapsules for Oral Delivery: Preparation and in Vitro Characterization.

    Science.gov (United States)

    Tomaro-Duchesneau, Catherine; Saha, Shyamali; Malhotra, Meenakshi; Coussa-Charley, Michael; Kahouli, Imen; Jones, Mitchell L; Labbé, Alain; Prakash, Satya

    2012-02-16

    Probiotics possess potential therapeutic and preventative effects for various diseases and metabolic disorders. One important limitation for the oral delivery of probiotics is the harsh conditions of the upper gastrointestinal tract (GIT) which challenge bacterial viability and activity. One proposed method to surpass this obstacle is the use of microencapsulation to improve the delivery of bacterial cells to the lower GIT. The aim of this study is to use alginate-poly-L-lysine-alginate (APA) microcapsules to encapsulate Lactobacillus fermentum NCIMB 5221 and characterize its enzymatic activity and viability through a simulated GIT. This specific strain, in previous research, was characterized for its inherent ferulic acid esterase (FAE) activity which could prove beneficial in the development of a therapeutic for the treatment and prevention of cancers and metabolic disorders. Our findings demonstrate that the APA microcapsule does not slow the mass transfer of substrate into and that of the FA product out of the microcapsule, while also not impairing bacterial cell viability. The use of simulated gastrointestinal conditions led to a significant 2.5 log difference in viability between the free (1.10 × 104 ± 1.00 × 103 cfu/mL) and the microencapsulated (5.50 × 106 ± 1.00 × 105 cfu/mL) L. fermentum NCIMB 5221 following exposure. The work presented here suggests that APA microencapsulation can be used as an effective oral delivery method for L. fermentum NCIMB 5221, a FAE-active probiotic strain.

  16. Errors in the 2017 APA Clinical Practice Guideline for the Treatment of PTSD: What the Data Actually Says.

    Science.gov (United States)

    Dominguez, Sarah K; Lee, Christopher W

    2017-01-01

    The American Psychological Association (APA) Practice Guidelines for the Treatment of Posttraumatic Stress Disorder (PTSD) concluded that there was strong evidence for cognitive behavioral therapy (CBT), cognitive processing therapy (CPT), cognitive therapy (CT), and exposure therapy yet weak evidence for eye movement desensitization and reprocessing (EMDR). This is despite the findings from an associated systematic review which concluded that EMDR leads to loss of PTSD diagnosis and symptom reduction. Depression symptoms were also found to improve more with EMDR than control conditions. In that review, EMDR was marked down on strength of evidence (SOE) for symptom reduction for PTSD. However, there were several problems with the conclusions of that review. Firstly, in assessing the evidence in one of the studies, the reviewers chose an incorrect measure that skewed the data. We recalculated a meta-analysis with a more appropriate measure and found the SOE improved. The resulting effect size for EMDR on PTSD symptom reduction compared to a control condition was large for studies that meet the APA inclusion criteria (SMD = 1.28) and the heterogeneity was low ( I 2 = 43%). Secondly, even if the original measure was chosen, we highlight inconsistencies with the way SOE was assessed for EMDR, CT, and CPT. Thirdly, we highlight two papers that were omitted from the analysis. One of these was omitted without any apparent reason. It found EMDR superior to a placebo control. The other study was published in 2015 and should have been part of APA guidelines since they were published in 2017. The inclusion of either study would have resulted in an improvement in SOE. Including both studies results in standard mean difference and confidence intervals that were better for EMDR than for CPT or CT. Therefore, the SOE should have been rated as moderate and EMDR assessed as at least equivalent to these CBT approaches in the APA guidelines. This would bring the APA guidelines in

  17. Errors in the 2017 APA Clinical Practice Guideline for the Treatment of PTSD: What the Data Actually Says

    Directory of Open Access Journals (Sweden)

    Sarah K. Dominguez

    2017-08-01

    Full Text Available The American Psychological Association (APA Practice Guidelines for the Treatment of Posttraumatic Stress Disorder (PTSD concluded that there was strong evidence for cognitive behavioral therapy (CBT, cognitive processing therapy (CPT, cognitive therapy (CT, and exposure therapy yet weak evidence for eye movement desensitization and reprocessing (EMDR. This is despite the findings from an associated systematic review which concluded that EMDR leads to loss of PTSD diagnosis and symptom reduction. Depression symptoms were also found to improve more with EMDR than control conditions. In that review, EMDR was marked down on strength of evidence (SOE for symptom reduction for PTSD. However, there were several problems with the conclusions of that review. Firstly, in assessing the evidence in one of the studies, the reviewers chose an incorrect measure that skewed the data. We recalculated a meta-analysis with a more appropriate measure and found the SOE improved. The resulting effect size for EMDR on PTSD symptom reduction compared to a control condition was large for studies that meet the APA inclusion criteria (SMD = 1.28 and the heterogeneity was low (I2= 43%. Secondly, even if the original measure was chosen, we highlight inconsistencies with the way SOE was assessed for EMDR, CT, and CPT. Thirdly, we highlight two papers that were omitted from the analysis. One of these was omitted without any apparent reason. It found EMDR superior to a placebo control. The other study was published in 2015 and should have been part of APA guidelines since they were published in 2017. The inclusion of either study would have resulted in an improvement in SOE. Including both studies results in standard mean difference and confidence intervals that were better for EMDR than for CPT or CT. Therefore, the SOE should have been rated as moderate and EMDR assessed as at least equivalent to these CBT approaches in the APA guidelines. This would bring the APA

  18. 我が国の事前確認(APA)の現状と課題 : 事前確認(APA)における納税者のジレンマ <研究ノート>

    OpenAIRE

    虫明, 千春; 佐伯, 健司

    2012-01-01

    移転価格税制の適用に係る問題に対しては,「移転価格事務運営要領」および「事前確認の状況─ APA レポート─」から確認できるとおり,事前確認制度による解決が図られており,特にバイラテラルAPA およびマルチラテラルAPA の利用が強く推奨されている。本研究ノートは,事前確認制度の意義を概観したうえで,納税者の立場から事前確認の利用におけるジレンマを指摘するものである。Givati(2009)の見解における事前確認を利用することによる懸念が,納税者におけるジレンマの一要因となっているものと考える。そのうえで,我が国の事前確認制度の法令による制度化を提言するものである。...

  19. “Citation Style Language” Uygulaması: APA Kaynak Gösterme Biçiminin Türkçeye Adaptasyonu=“Citation Style Language” Application: The Adaptation of APA Style to Turkish Language

    Directory of Open Access Journals (Sweden)

    Kasım Binici

    2013-10-01

    Full Text Available Bibliyografya yönetim programları, araştırma metinlerin yazımında yazarlara büyük avantajlar sağlamaktadır.Akademik çevrede EndNote, RefWorks, Zotero, Mendeley en popüler yazılımlardır. Türkçe kaynak gösterme kurallarının tanımlı olduğu biçim dosyalarının olmaması nedeniyle araştırma metni yazımında bu programlar işlevsiz kalmaktadır. Bu çalışmada, APA kaynak gösterme biçiminin Türkçeye adaptasyonu sağlanarak CSL uygulaması ile biçim dosyasında kodlar yazılmıştır. Yeni biçim dosyası Zotero ve Mendeley programlarında çalışabilirliği test edilerek kişilerin kullanımına sunulmuştur. Çalışma neticesinde oluşturulan APA-TR dosyası sayesinde Türkçe araştırma metinlerinin yazımında CSL uygulamasını tercih eden bibli- yografya yönetim yazılımların kullanımı mümkün olmuştur./Bibliography managment tools provide great advantage for researchers with writing their articles or research papers. In academic environment, EndNote, RefWorks, Zotero, Mendeley are the most popular software programms. Due to the lack of style files in which citation rules in Turkish language are described,these softwares stay functionless. In this study by providing turkish adaptation of APA citation style, new codes were written into the style file via CSL application. New style file is presented to users after testing its workability in Zotero and Mendeley programms. Thanks to APA-TR style file created as a result of the study,it is possibble to use bibliography managment tools which prefer CSL application in writing research papers Turkish language.

  20. Boosting BCG-primed responses with a subunit Apa vaccine during the waning phase improves immunity and imparts protection against Mycobacterium tuberculosis.

    Science.gov (United States)

    Nandakumar, Subhadra; Kannanganat, Sunil; Dobos, Karen M; Lucas, Megan; Spencer, John S; Amara, Rama Rao; Plikaytis, Bonnie B; Posey, James E; Sable, Suraj B

    2016-05-13

    Heterologous prime-boosting has emerged as a powerful vaccination approach against tuberculosis. However, optimal timing to boost BCG-immunity using subunit vaccines remains unclear in clinical trials. Here, we followed the adhesin Apa-specific T-cell responses in BCG-primed mice and investigated its BCG-booster potential. The Apa-specific T-cell response peaked 32-52 weeks after parenteral or mucosal BCG-priming but waned significantly by 78 weeks. A subunit-Apa-boost during the contraction-phase of BCG-response had a greater effect on the magnitude and functional quality of specific cellular and humoral responses compared to a boost at the peak of BCG-response. The cellular response increased following mucosal BCG-prime-Apa-subunit-boost strategy compared to Apa-subunit-prime-BCG-boost approach. However, parenteral BCG-prime-Apa-subunit-boost by a homologous route was the most effective strategy in-terms of enhancing specific T-cell responses during waning in the lung and spleen. Two Apa-boosters markedly improved waning BCG-immunity and significantly reduced Mycobacterium tuberculosis burdens post-challenge. Our results highlight the challenges of optimization of prime-boost regimens in mice where BCG drives persistent immune-activation and suggest that boosting with a heterologous vaccine may be ideal once the specific persisting effector responses are contracted. Our results have important implications for design of prime-boost regimens against tuberculosis in humans.

  1. Boosting BCG-primed responses with a subunit Apa vaccine during the waning phase improves immunity and imparts protection against Mycobacterium tuberculosis

    Science.gov (United States)

    Nandakumar, Subhadra; Kannanganat, Sunil; Dobos, Karen M.; Lucas, Megan; Spencer, John S.; Amara, Rama Rao; Plikaytis, Bonnie B.; Posey, James E.; Sable, Suraj B.

    2016-01-01

    Heterologous prime–boosting has emerged as a powerful vaccination approach against tuberculosis. However, optimal timing to boost BCG-immunity using subunit vaccines remains unclear in clinical trials. Here, we followed the adhesin Apa-specific T-cell responses in BCG-primed mice and investigated its BCG-booster potential. The Apa-specific T-cell response peaked 32–52 weeks after parenteral or mucosal BCG-priming but waned significantly by 78 weeks. A subunit-Apa-boost during the contraction-phase of BCG-response had a greater effect on the magnitude and functional quality of specific cellular and humoral responses compared to a boost at the peak of BCG-response. The cellular response increased following mucosal BCG-prime–Apa-subunit-boost strategy compared to Apa-subunit-prime–BCG-boost approach. However, parenteral BCG-prime–Apa-subunit-boost by a homologous route was the most effective strategy in-terms of enhancing specific T-cell responses during waning in the lung and spleen. Two Apa-boosters markedly improved waning BCG-immunity and significantly reduced Mycobacterium tuberculosis burdens post-challenge. Our results highlight the challenges of optimization of prime–boost regimens in mice where BCG drives persistent immune-activation and suggest that boosting with a heterologous vaccine may be ideal once the specific persisting effector responses are contracted. Our results have important implications for design of prime–boost regimens against tuberculosis in humans. PMID:27173443

  2. Vitamin D receptor gene Alw I, Fok I, Apa I, and Taq I polymorphisms in patients with urinary stone.

    Science.gov (United States)

    Seo, Ill Young; Kang, In-Hong; Chae, Soo-Cheon; Park, Seung Chol; Lee, Young-Jin; Yang, Yun Sik; Ryu, Soo Bang; Rim, Joung Sik

    2010-04-01

    To evaluate vitamin D receptor (VDR) gene polymorphisms in Korean patients so as to identify the candidate genes associated with urinary stones. Urinary stones are a multifactorial disease that includes various genetic factors. A normal control group of 535 healthy subjects and 278 patients with urinary stones was evaluated. Of 125 patients who presented stone samples, 102 had calcium stones on chemical analysis. The VDR gene Alw I, Fok I, Apa I, and Taq I polymorphisms were evaluated using the polymerase chain reaction-restriction fragment length polymorphism analysis. Allelic and genotypic frequencies were calculated to identify associations in both groups. The haplotype frequencies of the VDR gene polymorphisms for multiple loci were also determined. For the VDR gene Alw I, Fok I, Apa I, and Taq I polymorphisms, there was no statistically significant difference between the patients with urinary stones and the healthy controls. There was also no statistically significant difference between the patients with calcium stones and the healthy controls. A novel haplotype (Ht 4; CTTT) was identified in 13.5% of the patients with urinary stones and in 8.3% of the controls (P = .001). The haplotype frequencies were significantly different between the patients with calcium stones and the controls (P = .004). The VDR gene Alw I, Fok I, Apa I, and Taq I polymorphisms does not seem to be candidate genetic markers for urinary stones in Korean patients. However, 1 novel haplotype of the VDR gene polymorphisms for multiple loci might be a candidate genetic marker. Copyright 2010 Elsevier Inc. All rights reserved.

  3. Pautas para citar textos y hacer listas de referencias según las normas de la American Psichological Association (APA)

    OpenAIRE

    Ossa, Marcela

    2003-01-01

    La escritura de documentos, artículos, ensayos etc. implica seguir cuidadosamente algunas normas. La Revista EMA se guía para la edición de sus artículos por las normas de la American Psychological Association (APA). El presente documento tiene como objeto dar a conocer algunas de estas normas de tal modo que quien envíe un artículo para su publicación las utilice. Encontrarán algunas pautas para citar textos y hacer listas de referencias según las normas de la American Psychological Associat...

  4. La cita documental : elementos y ejemplos de referencias en los estilos de la MLA y de la APA. Documentos electrónicos ISO 690-2

    OpenAIRE

    Kolesas, Mabel; De-Volder, Carolina

    2008-01-01

    How to quote. Abridged style manual for writers of printed documents according to the Modern Language Association (MLA), the American Psychological Association (APA) and ISO 690-2 standards for E-documents.

  5. Competence to consent to voluntary psychiatric hospitalization: a test of a standard proposed by APA. American Psychiatric Association.

    Science.gov (United States)

    Appelbaum, B C; Appelbaum, P S; Grisso, T

    1998-09-01

    In the wake of the U.S. Supreme Court's 1990 decision in Zinermon v. Burch, renewed attention has been given to capacities patients must have to be considered competent to consent to voluntary hospitalization. An American Psychiatric Association (APA) task force suggested that strong policy interests support the establishment of a low threshold for competence in this situation. The study examined whether, as previous research suggested, patients would have difficulty meeting even this lenient standard. One hundred voluntarily hospitalized psychiatric patients were read two brief paragraphs, one explaining the purposes of psychiatric hospitalization and and the other explaining policies for discharge. The paragraphs' readability measured about eighth-grade level. After each paragraph, participants were read two sets of questions, one testing recall of the presented information and the other testing recognition of the information in a true-false format. The scores of patients grouped by selected demographic and clinical variables were compared. The vast majority of patients were able to comprehend the information that the APA task force suggested was relevant to their decision. However, a subgroup of patients who were initially admitted involuntarily had significantly poorer performance and may constitute a group who need special educational efforts focused on the consequences of voluntary admission.

  6. Développement d'un Gestionnaire Automatisé de Bibliographies selon les normes de l'American Psychological Association (GABI APA Style)

    OpenAIRE

    Thirion, Paul

    1992-01-01

    Nowadays, there are plenty of complete and user-friendly database management systems. However, most of them only produce poorly organized raw data, generally lacking of internal consistency. This situation remains awkward, especially for scientists who have regularly to report references in an extremely ruled international format. GABI APA Style was built in titis context. GABl APA Style is a reference manager software using the presentation rules of the American Psychological Association ...

  7. Performance and model of a full-scale up-flow anaerobic sludge blanket (UASB) to treat the pharmaceutical wastewater containing 6-APA and amoxicillin.

    Science.gov (United States)

    Chen, Zhiqiang; Wang, Hongcheng; Chen, Zhaobo; Ren, Nanqi; Wang, Aijie; Shi, Yue; Li, Xiaoming

    2011-01-30

    A full-scale test was conducted with an up-flow anaerobic sludge blanket (UASB) pre-treating pharmaceutical wastewater containing 6-aminopenicillanic acid (6-APA) and amoxicillin. The aim of the study is to investigate the performance of UASB in the condition of a high chemical oxygen demand (COD) loading rate from 12.57 to 21.02 kgm(-3)d(-1) and a wide pH from 5.57 to 8.26, in order to provide a reference for treating the similar chemical synthetic pharmaceutical wastewater containing 6-APA and amoxicillin. The results demonstrated that the UASB average percentage reduction in COD, 6-APA and amoxicillin were 52.2%, 26.3% and 21.6%, respectively. In addition, three models, built on the back propagation neural network (BPNN) theory and linear regression techniques were developed for the simulation of the UASB system performance in the biodegradation of pharmaceutical wastewater containing 6-APA and amoxicillin. The average error of COD, 6-APA and amoxicillin were -0.63%, 2.19% and 5.40%, respectively. The results indicated that these models built on the BPNN theory were well-fitted to the detected data, and were able to simulate and predict the removal of COD, 6-APA and amoxicillin by UASB. Crown Copyright © 2010. Published by Elsevier B.V. All rights reserved.

  8. Vitamin-D receptor (VDR) gene polymorphisms (Taq-I & Apa-I) in Syrian healthy population.

    Science.gov (United States)

    Haddad, Shaden

    2014-12-01

    The vitamin D endocrine system regulates bone metabolism and calcium homeostasis as well as cellular proliferation and differentiation. Vitamin D receptor (VDR) mediates Vit-D activity, thus VDR gene polymorphisms may correlate with different diseases. This study aimed to determine the distribution of VDR gene (Taq-I and Apa-I) polymorphisms using a RFLP in unrelated normal healthy individuals of Syrian population. Allelic frequencies were 65% vs 35% and 66% vs 34% for T vs t and A vs a alleles, respectively. Genotype distribution was 36%, 58% and 6% for TT, Tt and tt and 42%, 47% and 10% for AA, Aa and aa, respectively. These results demonstrate that the frequency and distribution of the VDR polymorphisms in Syrian population are different from other populations worldwide.

  9. IGF2/ApaI polymorphism associated with birth weight in children of the region of Petrolina-PE, Brazil.

    Science.gov (United States)

    de Mascena Diniz Maia, Paula F C; da Silva, Tamiris M E; Angelo, Hildson D; e Silva, Laís W; Gondim Martins, Danyelly B; de Mascena Diniz Maia, Maria; de Lima Filho, José L

    2013-02-01

    Insulin-like growth factor 2 (IGF2) gene has an important role in fetal growth. It was investigated association of the IGF2/ApaI polymorphism with low birth weight and normal birth weight (as control) in children attended in Hospital Dom Malan Petrolina, PE-Brazil. The genotype frequencies did not differ statistically between low birth weight (AA = 16.22%, AG = 43.24%, GG = 40.54%) and control (AA = 20% AG = 35%, GG= 45% groups) and the allele frequencies were not significantly different (p > 0.05).The observed genotype frequencies in both groups did not deviate significantly from Hardy-Weinberg equilibrium. Then, no significant correlation was found for this polymorphism in the population studied.

  10. Anti-herpes simplex virus 1 and immunomodulatory activities of a poly-γ- glutamic acid from Bacillus horneckiae strain APA of shallow vent origin.

    Science.gov (United States)

    Marino-Merlo, Francesca; Papaianni, Emanuela; Maugeri, Teresa L; Zammuto, Vincenzo; Spanò, Antonio; Nicolaus, Barbara; Poli, Annarita; Di Donato, Paola; Mosca, Claudia; Mastino, Antonio; Gugliandolo, Concetta

    2017-10-01

    Herpes simplex virus type 1 (HSV-1) is responsible of common and widespread viral infections in humans through the world, and of rare, but extremely severe, clinical syndromes in the central nervous system. The emergence of resistant strains to drugs actually in use encourages the searching for novel antiviral compounds, including those of natural origin. In this study, the recently described poly-γ-glutamic acid (γ-PGA-APA), produced by the marine thermotolerant Bacillus horneckiae strain APA, and previously shown to possess biological and antiviral activity, was evaluated for its anti-HSV-1 and immunomodulatory properties. The biopolymer hindered the HSV-1 infection in the very early phase of virus replication. In addition, the γ-PGA-APA was shown to exert low cytotoxicity and noticeable immunomodulatory activities towards TNF-α and IL-1β gene expression. Moreover, the capacity to positively modulate the transcriptional activity of the cytokine genes was paired with increased level of activation of the transcription factor NF-kB by γ-PGA-APA. Overall, as non-cytotoxic biopolymer able to contribute in the antiviral defense against HSV-1, γ-PGA-APA could lead to the development of novel natural drugs for alternative therapies.

  11. Calamitic Smectic A-Polar Smectic APA Transition Observed in Bent Molecules with Large Bent-Angle Central Core of 4,6-Dichlorobenzene and Alkylthio Terminal Tail

    Science.gov (United States)

    Nguyen, Ha; Kang, Sungmin; Tokita, Masatoshi; Watanabe, Junji

    2011-07-01

    New homologs of bent molecules with a large bent-angle central core of 4,6-dichloro benzene and an alkylthio terminal tail have been synthesized. Although the corresponding alkoxy-tail homologs show only the calamitic phases because of its large bent angles around 160°, the new homologs with an alkylthio tail exhibit the antiferroelectric smectic APA (SmAPA) banana phase that is transformed on cooling from the calamitic smectic A (SmA) phase. The biaxial polar packing of bent molecules in the SmAPA phase is considered to arise from the hindered rotation around the molecular long axis due to the expansion of the mesophase temperatures to a lower temperature region. This study indicates that the bent molecules, even with a large bent angle, have the potential to form a switchable banana phase with a remarkable decrease in its phase temperature range to around 60 °C.

  12. INCLUSÃO ESCOLAR: DEFICIÊNCIA INTELECTUAL E AS PRÁTICAS PEDAGÓGICAS DE EDUCAÇÃO FÍSICA DAS APAEs DE CURITIBA

    OpenAIRE

    Simão, Lucas Jorge

    2013-01-01

    Este trabalho é sobre a Inclusão Escolar: Deficiência Intelectual e as Práticas Pedagógicas de Educação Física das Associações de Pais e Amigos dos Excepcionais - APAE de Curitiba. Tem como interrogação central as práticas pedagógicas dos professores de Educação Física da APAE em relação à inclusão dos deficientes intelectuais? O sujeito desta pesquisa são os professores de educação física das APAE, sendo objeto de investigação as práticas pedagógicas para inclusão de alunos com deficiênci...

  13. [Phase transfer catalyzed bioconversion of penicillin G to 6-APA by immobilized penicillin acylase in recyclable aqueous two-phase systems with light/pH sensitive copolymers].

    Science.gov (United States)

    Jin, Ke-ming; Cao, Xue-jun; Su, Jin; Ma, Li; Zhuang, Ying-ping; Chu, Ju; Zhang, Si-liang

    2008-03-01

    Immobilized penicillin acylase was used for bioconversion of penicillin PG into 6-APA in aqueous two-phase systems consisting of a light-sensitive polymer PNBC and a pH-sensitive polymer PADB. Partition coefficients of 6-APA was found to be about 5.78 in the presence of 1% NaCl. Enzyme kinetics showed that the reaction reached equilibrium at roughly 7 h. The 6-APA mole yields were 85.3% (pH 7.8, 20 degrees C), with about 20% increment as compared with the reaction of single aqueous phase buffer. The partition coefficient of PG (Na) varied scarcely, while that of the product, 6-APA and phenylacetic acid (PA) significantly varied due to Donnan effect of the phase systems and hydrophobicity of the products. The variation of the partition coefficients of the products also affected the bioconversion yield of the products. In the aqueous two-phase systems, the substrate, PG, the products of 6-APA and PA were biased in the top phase, while immobilized penicillin acylase at completely partitioned at the bottom. The substrate and PG entered the bottom phase, where it was catalyzed into 6-APA and PA and entered the top phase. Inhibition of the substrate and products was removed to result in improvement of the product yield, and the immobilized enzyme showed higher efficiency than the immobilized cells and occupied smaller volume. Compared with the free enzyme, immobilized enzyme had greater stability, longer life-time, and was completely partitioned in the bottom phase and recycle. Bioconversion in two-phase systems using immobilized penicillin acylase showed outstanding advantage. The light-sensitive copolymer forming aqueous two-phase systems could be recovered by laser radiation at 488 nm or filtered 450 nm light, while pH-sensitive polymer PADB could be recovered at the isoelectric point (pH 4.1). The recovery of the two copolymers was between 95% and 99%.

  14. The O-mannosylation and production of recombinant APA (45/47 KDa protein from Mycobacterium tuberculosis in Streptomyces lividans is affected by culture conditions in shake flasks

    Directory of Open Access Journals (Sweden)

    Gamboa-Suasnavart Ramsés A

    2011-12-01

    Full Text Available Abstract Background The Ala-Pro-rich O-glycoprotein known as the 45/47 kDa or APA antigen from Mycobacterium tuberculosis is an immunodominant adhesin restricted to mycobacterium genus and has been proposed as an alternative candidate to generate a new vaccine against tuberculosis or for diagnosis kits. In this work, the recombinant O-glycoprotein APA was produced by the non-pathogenic filamentous bacteria Streptomyces lividans, evaluating three different culture conditions. This strain is known for its ability to produce heterologous proteins in a shorter time compared to M. tuberculosis. Results Three different shake flask geometries were used to provide different shear and oxygenation conditions; and the impact of those conditions on the morphology of S. lividans and the production of rAPA was characterized and evaluated. Small unbranched free filaments and mycelial clumps were found in baffled and coiled shake flasks, but one order of magnitude larger pellets were found in conventional shake flasks. The production of rAPA is around 3 times higher in small mycelia than in larger pellets, most probably due to difficulties in mass transfer inside pellets. Moreover, there are four putative sites of O-mannosylation in native APA, one of which is located at the carboxy-terminal region. The carbohydrate composition of this site was determined for rAPA by mass spectrometry analysis, and was found to contain different glycoforms depending on culture conditions. Up to two mannoses residues were found in cultures carried out in conventional shake flasks, and up to five mannoses residues were determined in coiled and baffled shake flasks. Conclusions The shear and/or oxygenation parameters determine the bacterial morphology, the productivity, and the O-mannosylation of rAPA in S. lividans. As demonstrated here, culture conditions have to be carefully controlled in order to obtain recombinant O-glycosylated proteins with similar "quality" in bacteria

  15. The O-mannosylation and production of recombinant APA (45/47 KDa) protein from Mycobacterium tuberculosis in Streptomyces lividans is affected by culture conditions in shake flasks.

    Science.gov (United States)

    Gamboa-Suasnavart, Ramsés A; Valdez-Cruz, Norma A; Cordova-Dávalos, Laura E; Martínez-Sotelo, José A; Servín-González, Luis; Espitia, Clara; Trujillo-Roldán, Mauricio A

    2011-12-20

    The Ala-Pro-rich O-glycoprotein known as the 45/47 kDa or APA antigen from Mycobacterium tuberculosis is an immunodominant adhesin restricted to mycobacterium genus and has been proposed as an alternative candidate to generate a new vaccine against tuberculosis or for diagnosis kits. In this work, the recombinant O-glycoprotein APA was produced by the non-pathogenic filamentous bacteria Streptomyces lividans, evaluating three different culture conditions. This strain is known for its ability to produce heterologous proteins in a shorter time compared to M. tuberculosis. Three different shake flask geometries were used to provide different shear and oxygenation conditions; and the impact of those conditions on the morphology of S. lividans and the production of rAPA was characterized and evaluated. Small unbranched free filaments and mycelial clumps were found in baffled and coiled shake flasks, but one order of magnitude larger pellets were found in conventional shake flasks. The production of rAPA is around 3 times higher in small mycelia than in larger pellets, most probably due to difficulties in mass transfer inside pellets. Moreover, there are four putative sites of O-mannosylation in native APA, one of which is located at the carboxy-terminal region. The carbohydrate composition of this site was determined for rAPA by mass spectrometry analysis, and was found to contain different glycoforms depending on culture conditions. Up to two mannoses residues were found in cultures carried out in conventional shake flasks, and up to five mannoses residues were determined in coiled and baffled shake flasks. The shear and/or oxygenation parameters determine the bacterial morphology, the productivity, and the O-mannosylation of rAPA in S. lividans. As demonstrated here, culture conditions have to be carefully controlled in order to obtain recombinant O-glycosylated proteins with similar "quality" in bacteria, particularly, if the protein activity depends on the

  16. Impactos ambientais na área de proteção ambiental (APA de Guaratuba, Paraná, BrasilL, sob o ponto de vista de moradores tradicionais / Environmental impacts in the Environmental Protection Area (APA of Guaratuba, State of Paraná, Brazil: the traditional communities point-of-view

    Directory of Open Access Journals (Sweden)

    Raphael Telles Kantek

    2009-08-01

    Full Text Available The present research was carried out in the Environmental Protection Area (APA of Guaratuba,State of Paraná, to analyze the environmental impacts of the APA as assessed by the local traditionalcommunities. Two instruments were used: Geographical Information System (GIS and Discourseof the Collective Subject (DSC. Although the GIS covers more situations that the DSC, results weresimilar. The pressures are complex and the analysis must involve the natural and traditionalcommunities.

  17. Empowerment of person with intellectual deficiency to the labor market in an APAE the south of Santa Catarina

    Directory of Open Access Journals (Sweden)

    Laysa Karoline Cardoso

    2016-12-01

    Full Text Available It is about a case study in an APAE the south of Santa Catarina, to know about the adopted actions from the institution in the empowerment to the inclusion of people with intellectual deficiency in the labor market. Nowadays the number of people with intellectual deficiency in the formal market is significantly smaller than the number of people with another kinds of deficiency and, in this direction, it is intended to enhance the consideration to the importance of this people empowerment. The design is from a qualitative nature and to the data collection was used the documentary analysis and the semi-directed interviews were done with the teachers and the multi-professional team involved in the professional empowerment. The data were analyzed based on the contents analysis. These are conclude as barriers to the inclusion to the labor market: the low profile from the students to the available job vacancy. Untying difficulty from the student’s family concerning about the earned benefit and family overprotection.

  18. The psychometric properties of the personality inventory for DSM-5 in an APA DSM-5 field trial sample.

    Science.gov (United States)

    Quilty, Lena C; Ayearst, Lindsay; Chmielewski, Michael; Pollock, Bruce G; Bagby, R Michael

    2013-06-01

    Section 3 of the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) includes a hybrid model of personality pathology, in which dimensional personality traits are used to derive one of seven categorical personality disorder diagnoses. The Personality Inventory for DSM-5 (PID-5) was developed by the DSM-5 Personality and Personality Disorders workgroup and their consultants to produce a freely available instrument to assess the personality traits within this new system. To date, the psychometric properties of the PID-5 have been evaluated primarily in undergraduate student and community adult samples. In the current investigation, we extend this line of research to a psychiatric patient sample who participated in the APA DSM-5 Field Trial (Centre for Addiction and Mental Health site). A total of 201 psychiatric patients (102 men, 99 women) completed the PID-5 and the Revised NEO Personality Inventory (NEO PI-R). The internal consistencies of the PID-5 domain and facet trait scales were acceptable. Results supported the unidimensional structure of all trait scales but one, and the convergence between the PID-5 and analogous NEO PI-R scales. Evidence for discriminant validity was mixed. Overall, the current investigation provides support for the psychometric properties of this diagnostic instrument in psychiatric samples.

  19. Prevalence of medicines used by mentally-ill individuals of APAE, in Londrina Prevalência de medicamentos utilizados por portadores de retardo mental da APAE de Londrina-Pr

    Directory of Open Access Journals (Sweden)

    Bruna Polacchine Da Silva

    2005-10-01

    Full Text Available Mental retardation (MR, after years of mites and beliefs, finally was considered to be a neurological affection that should be treated by a medical intervention. Psychotropic drugs, if correctly prescribed, are able to improve the capacity of MR individuals to productively interact socially and reintegrate themselves to the society. This work has as an objective to quantify, by a descriptive study, the frequency of use of medicines by students of the APAE (Associação de Pais e Amigos dos Excepcionais from Londrina-PR, characterize those drugs and relate them to mental pathologies of major prevalence in the institution. To accomplish the objectives, a pool was conducted on a population of 147 students registered during the period from January/1989 to May/ 2003. The results shown the following medicines: antiepiletic (52.4%, neuroleptics (3.4%, hematopoietics (2.7%, anticolinergics and pro-kinetics agents (0.7% each. Fenobarbital was the most evident among the antiepiletic (29.8%. The prevalence of those drugs was higher among individuals with cerebral palsy (62.1% and lower for the Down syndrome group (17,24%. As a conclusion, we consider necessary to conduct research projects focusing on the dynamic of the personnel affected by MR, as well as to provide social assistance to destitute families. O retardo mental (RM, após anos de crenças e misticismos, finalmente passou a ser considerado uma afecção neurológica que deve ser tratada com intervenção médica. As drogas psicotrópicas, se administradas corretamente, podem permitir que os acometidos de RM recuperem a capacidade de interação social produtiva e reintegrem-se à sociedade. Este trabalho teve como objetivo verificar, por meio de estudo descritivo, a freqüência da utilização de medicamentos utilizados pelos alunos da APAE (Associação de Pais e Amigos dos Excepcionais de Londrina-PR, caracterizar essas drogas e relacionálas com as patologias mentais de maior prevalência na

  20. Effect of oxygen and nitroaromatic cell radiosensitizers on radiation-induced cleavage of internucleotide bonds: ApA, dApA, and poly(A)

    International Nuclear Information System (INIS)

    Raleigh, J.A.; Kremers, W.; Whitehouse, R.

    1975-01-01

    Irradiation of the dinucleoside monophosphates ApA and dApA in deoxygenated solution leads to a preferential cleavage of the 3' end of the internucleotide bond. Cleavage at the 3' bond is favored to the extent of 2 to 1 over 5' cleavage. Oxygen and nitroaromatic compounds inhibit 3' bond breaking in ApA and dApA in agreement with earlier findings from studies of 3'- and 5'-mononucleotides. In contrast to the mononucleotide results, no enhancement of 5' cleavage is observed for ApA and dApA irradiated in the presence of oxygen or the nitroaromatic additives. The over-all effect of the additives is to decrease the combined (3' and 5') yield of internucleotide bond breaking in ApA and dApA. This phenomenon is also observed for polyadenylic acid in the presence of the nitroaromatics. Oxygen marginally enhances internucleotide bond breaking in polyadenylic acid (factor 1.1) over that seen in deoxygenated solution. Postirradiation alkaline hydrolysis of dApA leads to further ester cleavage revealing the presence of radiation-induced alkali-labile bonds. The number of these bonds decreases in the order oxygen greater than nitrofurans greater than nitrobenzenes approximately irradiation in the absence of additives

  1. Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen activator (aPA) and induces proinflammatory cytokine in human corneal epithelial cells.

    Science.gov (United States)

    Tripathi, Trivendra; Abdi, Mahshid; Alizadeh, Hassan

    2014-05-29

    Acanthamoeba plasminogen activator (aPA) is a serine protease elaborated by Acanthamoeba trophozoites that facilitates the invasion of trophozoites to the host and contributes to the pathogenesis of Acanthamoeba keratitis (AK). The aim of this study was to explore if aPA stimulates proinflammatory cytokine in human corneal epithelial (HCE) cells via the protease-activated receptors (PARs) pathway. Acanthamoeba castellanii trophozoites were grown in peptone-yeast extract glucose for 7 days, and the supernatants were collected and centrifuged. The aPA was purified using the fast protein liquid chromatography system, and aPA activity was determined by zymography assays. Human corneal epithelial cells were incubated with or without aPA (100 μg/mL), PAR1 agonists (thrombin, 10 μM; TRAP-6, 10 μM), and PAR2 agonists (SLIGRL-NH2, 100 μM; AC 55541, 10 μM) for 24 and 48 hours. Inhibition of PAR1 and PAR2 involved preincubating the HCE cells for 1 hour with the antagonist of PAR1 (SCH 79797, 60 μM) and PAR2 (FSLLRY-NH2, 100 μM) with or without aPA. Human corneal epithelial cells also were preincubated with PAR1 and PAR2 antagonists and then incubated with or without PAR1 agonists (thrombin and TRAP-6) and PAR2 agonists (SLIGRL-NH2 and AC 55541). Expression of PAR1 and PAR2 was examined by quantitative RT-PCR (qRT-PCR), flow cytometry, and immunocytochemistry. Interleukin-8 expression was quantified by qRT-PCR and ELISA. Human corneal epithelial cells constitutively expressed PAR1 and PAR2 mRNA. Acanthamoeba plasminogen activator and PAR2 agonists significantly upregulated PAR2 mRNA expression (1- and 2-fold, respectively) (P aPA, and PAR2 agonists induced PAR2 mRNA expression in HCE cells (P aPA, significantly upregulated PAR1 mRNA expression, which was significantly inhibited by PAR1 antagonist in HCE cells. Acanthamoeba plasminogen activator and PAR2 agonists stimulated IL-8 mRNA expression and protein production, which is significantly diminished by PAR2 antagonist

  2. Journal article reporting standards for qualitative primary, qualitative meta-analytic, and mixed methods research in psychology: The APA Publications and Communications Board task force report.

    Science.gov (United States)

    Levitt, Heidi M; Bamberg, Michael; Creswell, John W; Frost, David M; Josselson, Ruthellen; Suárez-Orozco, Carola

    2018-01-01

    The American Psychological Association Publications and Communications Board Working Group on Journal Article Reporting Standards for Qualitative Research (JARS-Qual Working Group) was charged with examining the state of journal article reporting standards as they applied to qualitative research and with generating recommendations for standards that would be appropriate for a wide range of methods within the discipline of psychology. These standards describe what should be included in a research report to enable and facilitate the review process. This publication marks a historical moment-the first inclusion of qualitative research in APA Style, which is the basis of both the Publication Manual of the American Psychological Association (APA, 2010) and APA Style CENTRAL, an online program to support APA Style. In addition to the general JARS-Qual guidelines, the Working Group has developed standards for both qualitative meta-analysis and mixed methods research. The reporting standards were developed for psychological qualitative research but may hold utility for a broad range of social sciences. They honor a range of qualitative traditions, methods, and reporting styles. The Working Group was composed of a group of researchers with backgrounds in varying methods, research topics, and approaches to inquiry. In this article, they present these standards and their rationale, and they detail the ways that the standards differ from the quantitative research reporting standards. They describe how the standards can be used by authors in the process of writing qualitative research for submission as well as by reviewers and editors in the process of reviewing research. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  3. Do Biochemical Markers and Apa I Polymorphism in IGF-II Gene Play a Role in the Association of Birth Weight and Later BMI?

    Science.gov (United States)

    Wu, Junqing; Ren, Jingchao; Li, Yuyan; Wu, Yinjie; Gao, Ersheng

    2013-01-01

    The aim of the study was to explore the mechanisms underlying the association of birth weight with later body mass index (BMI) from the biochemical markers related to metabolism and the Apa I polymorphism in IGF-II gene. A total of 300 children were selected randomly from the Macrosomia Birth Cohort in Wuxi, China. The height and weight were measured and blood samples were collected. Plasma concentrations of 8 biochemical markers were detected. Apa I polymorphism was analyzed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Biochemical markers were detected for 296 subjects and 271 subjects were genotyped for the Apa I polymorphism. No association was found between birth weight and 8 biochemical markers. In boys, the BMIs of AA, AG and GG genotypes were 16.10 ± 2.24 kg/m(2), 17.40 ± 3.20 kg/m(2), 17.65 ± 2.66 kg/m(2). And there was statistical difference among the three genotypes. But in girls, there was no statistical difference. The birth weights of AA, AG and GG genotypes were 3751.13 ± 492.43 g, 3734.00 ± 456.88 g, 3782.00 ± 461.78 g. And there was no statistical difference among the three genotypes. Biochemical markers are not associated with birth weight. Apa I polymorphism may be related to childhood BMI, but it may be not associated with birth weight. Therefore, biochemical markers and Apa I polymorphism might not play a role in the association of birth weight and BMI.

  4. Introduction to the special issue: 50th anniversary of APA Division 28: The past, present, and future of psychopharmacology and substance abuse.

    Science.gov (United States)

    Stoops, William W; Sigmon, Stacey C; Evans, Suzette M

    2016-08-01

    This is an introduction to the special issue "50th Anniversary of APA Division 28: The Past, Present, and Future of Psychopharmacology and Substance Abuse." Taken together, the scholarly contributions included in this special issue serve as a testament to the important work conducted by our colleagues over the past five decades. Division 28 and its members have advanced and disseminated knowledge on the behavioral effects of drugs, informed efforts to prevent and treat substance abuse, and influenced education and policy issues more generally. As past and current leaders of the division, we are excited to celebrate 50 years of Division 28 and look forward to many more successful decades for our division and its members. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  5. Lack of association between vitamin D receptor BsmI, ApaI polymorphisms and osteoporosis risk: A pooled analysis on Chinese individuals.

    Science.gov (United States)

    Wang, Qing-Xian; Zhao, Shi-Meng; Zhou, Ya-Bin; Zhang, Cheng

    2018-04-06

    As for the association between vitamin D receptor (VDR) gene polymorphisms and osteoporosis, the current results have yielded conflicts. Therefore, we performed a pooled analysis based on Chinese individuals to provide comprehensive data on the association between VDR BsmI, ApaI, Tru9I polymorphisms and osteoporosis risk. Studies were identified using PubMed, Springer Link, Ovid, Chinese Wanfang Data Knowledge Service Platform, Chinese National Knowledge Infrastructure and Chinese Biology Medicine databases through to January 2017. Studies were screened according to the predefined inclusion and exclusion criteria. The association between VDR BsmI, ApaI, Tru9I polymorphisms and osteoporosis was evaluated by calculating pooled odds ratios (ORs) based on the individual ORs. The significance of the pooled OR was evaluated by a Z-test. All statistical analyses were conducted using Stata 12.0 software (StataCorp, College Station, TX, USA). A total of 13 studies with 1141 osteoporosis cases and 1263 controls were included in this meta-analysis. It revealed that VDR Tru9I polymorphism was associated with an increased risk of osteoporosis in a common model (OR = 2.67, CI 95% = 1.59-4.49). No significant association was observed between VDR BsmI, ApaI and osteoporosis. In conclusion, this meta-analysis suggests that VDR Tru9I polymorphism may be associated with osteoporosis risk in Chinese individuals, while BsmI, ApaI polymorphisms might not be a risk factor for osteoporosis. © 2018 Asia Pacific League of Associations for Rheumatology and John Wiley & Sons Australia, Ltd.

  6. O-mannosylation of the Mycobacterium tuberculosis adhesin Apa is crucial for T cell antigenicity during infection but is expendable for protection.

    Science.gov (United States)

    Nandakumar, Subhadra; Kannanganat, Sunil; Dobos, Karen M; Lucas, Megan; Spencer, John S; Fang, Sunan; McDonald, Melissa A; Pohl, Jan; Birkness, Kristin; Chamcha, Venkateswarlu; Ramirez, Melissa V; Plikaytis, Bonnie B; Posey, James E; Amara, Rama Rao; Sable, Suraj B

    2013-01-01

    Glycosylation is the most abundant post-translational polypeptide chain modification in nature. Although carbohydrate modification of protein antigens from many microbial pathogens constitutes important components of B cell epitopes, the role in T cell immunity is not completely understood. Here, using ELISPOT and polychromatic flow cytometry, we show that O-mannosylation of the adhesin, Apa, of Mycobacterium tuberculosis (Mtb) is crucial for its T cell antigenicity in humans and mice after infection. However, subunit vaccination with both mannosylated and non-mannosylated Apa induced a comparable magnitude and quality of T cell response and imparted similar levels of protection against Mtb challenge in mice. Both forms equally improved waning BCG vaccine-induced protection in elderly mice after subunit boosting. Thus, O-mannosylation of Apa is required for antigenicity but appears to be dispensable for its immunogenicity and protective efficacy in mice. These results have implications for the development of subunit vaccines using post-translationally modified proteins such as glycoproteins against infectious diseases like tuberculosis.

  7. Preparation, crystallization and preliminary X-ray analysis of XC2382, an ApaG protein of unknown structure from Xanthomonas campestris

    International Nuclear Information System (INIS)

    Chin, Ko-Hsin; Chou, Chia-Cheng; Lee, Cheng-Chung; Shr, Hui-Lin; Lyu, Ping-Chiang; Wang, Andrew H.-J.; Chou, Shan-Ho

    2005-01-01

    A putative ApaG gene product from X. campestris pv. campestris was overexpressed in E. coli, purified and crystallized. The crystals diffracted to a resolution of at least 2.3 Å. Xanthomonas campestris pv. campestris is the causative agent of black rot, one of the major worldwide diseases of cruciferous crops. Its genome encodes approximately 4500 proteins, roughly one third of which have unknown function. XC2382 is one such protein, with a MW of 14.2 kDa. Based on a bioinformatics study, it was annotated as an ApaG gene product that serves multiple functions. The ApaG protein has been overexpressed in Escherichia coli, purified and crystallized using the hanging-drop vapour-diffusion method. The crystals diffracted to a resolution of at least 2.30 Å. They are tetragonal and belong to space group P4 1/3 , with unit-cell parameters a = b = 57.6, c = 122.9 Å. There are two, three or four molecules in the asymmetric unit

  8. Apa-I polymorphism in VDR gene is related to metabolic syndrome in polycystic ovary syndrome: a cross-sectional study.

    Science.gov (United States)

    Santos, Betânia Rodrigues; Lecke, Sheila Bunecker; Spritzer, Poli Mara

    2018-04-18

    Polycystic ovary syndrome (PCOS) is a common endocrine disorder determined by polygenic traits as well as environmental factors. Lower vitamin D levels have been detected in PCOS women and related to hormone and metabolic disturbances. Vitamin D acts in tissues through the vitamin D receptor (VDR). VDR gene variants have been associated with worse metabolic profile in the general population. We investigated the genotype and haplotype distribution of the Bsm-I (rs1544410), Apa-I (rs7975232), and Taq-I (rs731236) VDR gene polymorphisms in PCOS and non-hirsute women from southern Brazil. We further investigated the associations of these gene variants and their haplotypes with PCOS, vitamin D levels, and metabolic abnormalities, including the metabolic syndrome (MetS). A group of 191 women with PCOS (Rotterdam criteria) and 100 non-hirsute controls with regular ovulatory cycles were genotyped for all polymorphisms by real-time PCR, with allelic discrimination assays. MetS and the cutoffs for its isolated components were defined in accordance with the Joint Scientific Statement. Women with PCOS were younger and had significantly higher BMI and total testosterone levels than controls (p Apa-I entailed higher risk of MetS in PCOS (OR: 2.133; 95% CI 1.020-4.464, p = 0.042), and was associated with higher systolic blood pressure (p = 0.009), total cholesterol (p = 0.040), and LDL-cholesterol (p = 0.038) in both PCOS and control groups (two-way ANOVA). The frequencies of VDR haplotypes were similar in PCOS and control women. The present results suggest that the Apa-I variant in VDR gene may be associated with MetS in southern Brazilian women with PCOS, and with blood pressure, total cholesterol, and LDL-c in women with and without PCOS.

  9. NASA AVOSS Fast-Time Models for Aircraft Wake Prediction: User's Guide (APA3.8 and TDP2.1)

    Science.gov (United States)

    Ahmad, Nash'at N.; VanValkenburg, Randal L.; Pruis, Matthew J.; Limon Duparcmeur, Fanny M.

    2016-01-01

    NASA's current distribution of fast-time wake vortex decay and transport models includes APA (Version 3.8) and TDP (Version 2.1). This User's Guide provides detailed information on the model inputs, file formats, and model outputs. A brief description of the Memphis 1995, Dallas/Fort Worth 1997, and the Denver 2003 wake vortex datasets is given along with the evaluation of models. A detailed bibliography is provided which includes publications on model development, wake field experiment descriptions, and applications of the fast-time wake vortex models.

  10. ApaI polymorphism of vitamin D receptor affects health-related quality of life in patients with primary sclerosing cholangitis.

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    Agnieszka Kempinska-Podhorodecka

    Full Text Available Polymorphisms of vitamin D receptor (VDR contribute to the pathogenesis of multiple autoimmune conditions.We investigated the incidence of VDR polymorphisms (rs1544410-BsmI; rs7975232-ApaI; rs731236-TaqI in a group of patients with primary sclerosing cholangitis (PSC, n = 275 and in healthy controls (n = 376. Additionally, correlations of the VDR polymorphisms with clinical and biochemical factors of the disease were analysed.The genotype and allele distributions of these polymorphisms in PSC patients were similar to those observed in controls. However, the ApaI polymorphism was associated with an impaired health-related quality of life (HRQoL. The generic SF-36 questionnaire showed that the Role-Physical (p = 0.01, Role-Emotional (p = 0.01, Physical Component Summary (p = 0.01 and Mental Component Summary (p = 0.003 scores were significantly affected. Similarly, the disease-specific questionnaires, PBC-40 and PBC-27, demonstrated that carriers of the C allele suffered from more severe Itch (p = 0.03 assessed by PBC-40 and PBC-27, more Fatigue (p = 0.02 assessed by PBC-40 and PBC-27 and Impaired Cognitive Capacity (p = 0.04 and p = 0.03. Correspondingly, individuals who were AA homozygotes (non-carriers of the C allele of ApaI had higher summary scores for the Physical (p = 0.01 and Mental Components (p = 0.006 measured with SF-36. Moreover, they experienced less itch (p = 0.03 and less Fatigue (p = 0.03 and had better Cognitive Abilities (p = 0.04 as assessed by the PBC-40 and PBC-27 questionnaires. No associations between other VDR polymorphisms and clinical or laboratory findings were made.In summary, this study is the first to show that the ApaI polymorphisms in VDR may exert an effect on disease-related symptoms and quality of life in patients with PSC.

  11. The h index of the presidents of the American Psychological Association (APA through journal articles included in the Web of Science database

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    Gualberto Buela-Casal

    2011-01-01

    Full Text Available El presente estudio descriptivo analiza los índices h de los presidentes de la American Psychological Association (APA desde 1940 hasta la actualidad. El índice h se calcula teniendo en cuenta el número de artículos publicados en las revistas de la Web of Science (WOS y las citas recibidas por los mismos en dicha base de datos. No se estableció un periodo de búsqueda y, por tanto, se analizaron todos los resultados incluidos en la WOS. El número total de resultados analizados fue de 16.676, de los cuales 3.734 fueron de los presidentes de la APA. Los resultados se presentan en forma de ranking y ponen de manifiesto que Albert Bandura y Alan Kazdin son los presidentes con un índice h más elevado, y en entre estos y los demás existe una diferencia considerable. Los resultados hacen especular que el criterio de productividad en artículos científicos no fue el criterio más importante para presidir esta institución.

  12. Hydrolysis of ibuprofenoyl-CoA and other 2-APA-CoA esters by human acyl-CoA thioesterases-1 and -2 and their possible role in the chiral inversion of profens.

    Science.gov (United States)

    Qu, Xiao; Allan, Amanda; Chui, Grace; Hutchings, Thomas J; Jiao, Ping; Johnson, Lawrence; Leung, Wai Y; Li, Portia K; Steel, Georgina R; Thompson, Andrew S; Threadgill, Michael D; Woodman, Timothy J; Lloyd, Matthew D

    2013-12-01

    Ibuprofen and related 2-arylpropanoic acid (2-APA) drugs are often given as a racemic mixture and the R-enantiomers undergo activation in vivo by metabolic chiral inversion. The chiral inversion pathway consists of conversion of the drug to the coenzyme A ester (by an acyl-CoA synthetase) followed by chiral inversion by α-methylacyl-CoA racemase (AMACR; P504S). The enzymes responsible for hydrolysis of the product S-2-APA-CoA ester to the active S-2-APA drug have not been identified. In this study, conversion of a variety of 2-APA-CoA esters by human acyl-CoA thioesterase-1 and -2 (ACOT-1 and -2) was investigated. Human recombinant ACOT-1 and -2 (ACOT-1 and -2) were both able to efficiently hydrolyse a variety of 2-APA-CoA substrates. Studies with the model substrates R- and S-2-methylmyristoyl-CoA showed that both enzymes were able to efficiently hydrolyse both of the epimeric substrates with (2R)- and (2S)- methyl groups. ACOT-1 is located in the cytosol and is able to hydrolyse 2-APA-CoA esters exported from the mitochondria and peroxisomes for inhibition of cyclo-oxygenase-1 and -2 in the endoplasmic reticulum. It is a prime candidate to be the enzyme responsible for the pharmacological action of chiral inverted drugs. ACOT-2 activity may be important in 2-APA toxicity effects and for the regulation of mitochondrial free coenzyme A levels. These results support the idea that 2-APA drugs undergo chiral inversion via a common pathway. Copyright © 2013 Elsevier Inc. All rights reserved.

  13. LEVANTAMENTO EPIDEMIOLÓGICO DAS DOENÇAS CÁRIE E PERIODONTAL EM ALUNOS COM NECESSIDADES ESPECIAIS DAS APAE NA REGIÃO METROPOLITANA DE CURITIBA - PARANÁ

    OpenAIRE

    MARISSOL CRISTINA MARIA DE OLIVEIRA VASCONCELLOS ROMANELLI

    2006-01-01

    O objetivo desta dissertação foi analisar as condições de saúde bucal em alunos com necessidades especiais, atendidos nas Associações de Pais e Amigos dos Excepcionais (APAE) de quatorze municípios da Região Metropolitana de Curitiba PR. Para este estudo, foi feito um levantamento da prevalência da doença cárie e condição periodontal, utilizando-se os índices ceod e CPOD, o índice periodontal comunitário (IPC) para dentadura permanente ou mista e o índice de alteração gengival (AG) para a de...

  14. APA Summit on Medical Student Education Task Force on Informatics and Technology: learning about computers and applying computer technology to education and practice.

    Science.gov (United States)

    Hilty, Donald M; Hales, Deborah J; Briscoe, Greg; Benjamin, Sheldon; Boland, Robert J; Luo, John S; Chan, Carlyle H; Kennedy, Robert S; Karlinsky, Harry; Gordon, Daniel B; Yager, Joel; Yellowlees, Peter M

    2006-01-01

    This article provides a brief overview of important issues for educators regarding medical education and technology. The literature describes key concepts, prototypical technology tools, and model programs. A work group of psychiatric educators was convened three times by phone conference to discuss the literature. Findings were presented to and input was received from the 2005 Summit on Medical Student Education by APA and the American Directors of Medical Student Education in Psychiatry. Knowledge of, skills in, and attitudes toward medical informatics are important to life-long learning and modern medical practice. A needs assessment is a starting place, since student, faculty, institution, and societal factors bear consideration. Technology needs to "fit" into a curriculum in order to facilitate learning and teaching. Learning about computers and applying computer technology to education and clinical care are key steps in computer literacy for physicians.

  15. A single dose of a DNA vaccine encoding apa coencapsulated with 6,6'-trehalose dimycolate in microspheres confers long-term protection against tuberculosis in Mycobacterium bovis BCG-primed mice.

    Science.gov (United States)

    Carlétti, Dyego; Morais da Fonseca, Denise; Gembre, Ana Flávia; Masson, Ana Paula; Weijenborg Campos, Lívia; Leite, Luciana C C; Rodrigues Pires, Andréa; Lannes-Vieira, Joseli; Lopes Silva, Célio; Bonato, Vânia Luiza Deperon; Horn, Cynthia

    2013-08-01

    Mycobacterium bovis BCG prime DNA (Mycobacterium tuberculosis genes)-booster vaccinations have been shown to induce greater protection against tuberculosis (TB) than BCG alone. This heterologous prime-boost strategy is perhaps the most realistic vaccination for the future of TB infection control, especially in countries where TB is endemic. Moreover, a prime-boost regimen using biodegradable microspheres seems to be a promising immunization to stimulate a long-lasting immune response. The alanine proline antigen (Apa) is a highly immunogenic glycoprotein secreted by M. tuberculosis. This study investigated the immune protection of Apa DNA vaccine against intratracheal M. tuberculosis challenge in mice on the basis of a heterologous prime-boost regimen. BALB/c mice were subcutaneously primed with BCG and intramuscularly boosted with a single dose of plasmid carrying apa and 6,6'-trehalose dimycolate (TDM) adjuvant, coencapsulated in microspheres (BCG-APA), and were evaluated 30 and 70 days after challenge. This prime-boost strategy (BCG-APA) resulted in a significant reduction in the bacterial load in the lungs, thus leading to better preservation of the lung parenchyma, 70 days postinfection compared to BCG vaccinated mice. The profound effect of this heterologous prime-boost regimen in the experimental model supports its development as a feasible strategy for prevention of TB.

  16. ADA APA DENGAN KECEMASAN MATEMATIKA?

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    Fatrima Santri Syafri

    2017-01-01

    ABSTRACT Math anxiety is one of the factors that affect mathematics achievement. These factors can be influenced by several things, both with regard to internal factors and external factors learners. In this paper will discuss what it is about math anxiety, math anxiety indicators, impacts, and how to overcome them. Based on several studies of math anxiety, math anxiety appears that negatively affect the results of the teaching / learning achievement and influence to the mathematical abilities of learners. As a teacher or prospective teacher should also reduce math anxiety so as to reduce math anxiety owned by students. So that when giving instruction error does not occur in the delivery and may reduce students' mathematical anxiety. A teacher/tutors should understand how math anxiety indicator of students, so as to overcome math anxiety that occurs in students.at home. Keywords: math anxiety.

  17. Segregação social como externalização de conflitos ambientais: a elitização do meio ambiente na APA-Sul, Região Metropolitana de Belo Horizonte Social segregation like externalizing environmental problems: the elitization of the environment in the APA-Sul, Metropolitan Region of Belo Horizonte

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    Klemens Laschefski

    2008-01-01

    Full Text Available Este trabalho trata das relações de poder no conselho consultivo da APA-Sul, uma unidade de conservação localizada na Região Metropolitana de Belo Horizonte. Observa-se uma sub-representação dos setores populares, e os representantes de renda média-alta temem a favelização da região. Conseqüentemente, o conflito ambiental surge em torno da perda da qualidade ambiental nas referidas áreas, em parte associada às alternativas de habitação popular, abrindo oportunidade para discursos que justifiquem a segregação social no espaço e a elitização da paisagem em questão.This paper talks about the power relations within the consultative council of the APA-Sul, a conservation area situated in the Metropolitan Region of Belo Horizonte. There the lower-class sectors are apparently underrepresented and higher middle class representatives are concerned about the slumisation of the region. Consequently an environmental conflict arises about the loss of "environmental quality" of the area, partly associated with lower class housing, providing opportunities of discourses to justify social segregation in space and the elitization of the landscape at stake.

  18. Procedimentos didático-metodológicos utilizados pelos professores da APAE no processo de alfabetização dos alunos portadores de deficiência mental moderada

    OpenAIRE

    Lima, Terezinha de Fátima Aguiar de

    2002-01-01

    O objetivo desta pesquisa foi identificar os procedimentos didático-metodológicos utilizados pelos professores da APAE no processo de alfabetização dos alunos Portadores de Necessidades Educativas Especiais na área mental em nível moderado. Esta pesquisa caracterizou-se como sendo um estudo longitudinal onde investigou-se padrões de mudanças ocorridos durante a vida escolar dos alunos PNEE de uma escola especial da APAE. Neste sentido, procuro ao longo dos capítulos, encamin...

  19. -CH2- lengthening of the internucleotide linkage in the ApA dimer can improve its conformational compatibility with its natural polynucleotide counterpart

    Science.gov (United States)

    Hanu, J.; Barvík, I.; Ruszová-Chmelová, K.; ŠtÆpánek, J.; Turpin, P.-Y.; Bok, J.; Rosenberg, I.; Petrová-Endová, M.

    2001-01-01

    The complete family of ApA phosphonate analogues with the internucleotide linkage elongated by insertion of a -CH2- group was prepared and the hybridisation and structural properties of its members in interaction with polyuridylic acid were investigated using an original 2D Raman approach. Except for the conformationally restricted ACHpA(2′3′endo-5′) modification, all of the isopolar, non-isosteric analogues form triplex-like complexes with poly(rU) at room temperature, in which two polymer strands are bound by Watson–Crick and Hoogsteen bonds to a central pseudostrand consisting of a ‘chain’ of A-dimers. For all of these dimers, the overall conformation of the triplexes was found to be similar according to their extracted Raman spectra. A simple semi-empirical model was introduced to explain the observed dependency of the efficiency of triplex formation on the adenine concentration. Apparently, for most of the modifications studied, the creation of a stable complex at room temperature requires the formation of a central pseudostrand, consisting of several adenine dimers. Molecular dynamics calculations were finally performed to interpret the differences in ‘cooperative’ behaviour between the different dimers studied. The results indicate that the exceptional properties of the ApCH2A(3′-5′) dimer could be caused by the 3D conformational compatibility of this modified linkage with the second (Hoogsteen) poly(rU) strand. PMID:11812852

  20. RELAÇÕES DE TRABALHO NO TERCEIRO SETOR: UM ESTUDO EM ASSOCIAÇÕES DE PAIS E AMIGOS DOS EXCEPCIONAIS (APAEs

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    Amanda Burchert

    2017-03-01

    Full Text Available O objetivo deste artigo é identificar aspectos da relação de trabalho existentes em organizações do terceiro setor. A pesquisa se constituiu por uma análise qualitativa e exploratória a partir de entrevistas com gestores de APAEs. Os resultados obtidos indicam a predominância de práticas de contratação e demissão como modalidades de mediação dos vínculos, realizada em parceria com as prefeituras locais. A cedência de servidores pelo município, a ausência de profissionais qualificados na região pesquisada e a identificação dos trabalhadores com as demandas e características das instituições são desafios presentes nestas organizações. Diferentemente do aspecto majoritário do terceiro setor, nas instituições pesquisadas não há membros voluntários em virtude do receio de ações trabalhistas e reduzida articulação da comunidade. Observa-se que a diretoria tem participação efetiva nas decisões, em conjunto com a coordenação pedagógica, e há multifuncionalidade nos processos de trabalho em função do quadro de pessoal restrito.

  1. Qualidade da pastagem nativa obtida por diferentes métodos de amostragem e em diferentes solos na Apa do Ibirapuitã, Brasil Quality of natural pasture evaluated with different methods and soils at the Apa of Ibirapuitã, Brazil

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    Vicente Celestino Pires Silveira

    2005-06-01

    Full Text Available O estado do Rio Grande do Sul apresenta ecossistemas heterogêneos, devido ao grande número de tipos de solo e à variação em altitude e clima, que se reflete na diversidade da composição florística das diferentes comunidades vegetais. A Área de Proteção Ambiental do Ibirapuitã (APA do Ibirapuitã, é a única unidade de conservação federal, representante do bioma campos sulinos no Brasil. O objetivo deste trabalho foi obter informação sobre a qualidade do campo natural oriundo de três tipos de solos predominantes na APA do Ibirapuitã: Basalto superficial, Basalto profundo e Arenito obtidos por três formas de amostragem: Corte de emparelhamento, Simulação de pastejo através de coleta manual e Corte total acima da fração mantilho. Os dados foram coletados mensalmente, no período de outubro/2001 a setembro/2003. A pastagem nativa no solo de Basalto superficial apresenta forragem com qualidade nutricional superior quando comparado ao Basalto profundo e ao Arenito, comprovada pelas diferentes análises de qualidade realizadas. O método de coleta de amostras de forragem de pastagem nativa somente não influencia os resultados da análise de Fibra em Detergente Neutro. Os resultados indicam a simulação de pastejo como um método adequado de amostragem para avaliação da qualidade da pastagem nativa, devido à sua efetividade e facilidade de coleta.Heterogeneous ecosystems are found in the state of Rio Grande do Sul as a consequence of the great number of soil types and variation in altitude and climate. These conditions reflect on the great variety of flora present in the grassland communities. The Area of Environmental Protection of the Ibirapuitã (APA of Ibirapuitã is the only conservation unit under federal jurisdiction representative of the Campos bioma in Brazil. The objective of this work was to obtain information about the quality of the natural pasture on three types of soils in APA of Ibirapuitã: Superficial

  2. The Mycobacterium tuberculosis cell-surface glycoprotein apa as a potential adhesin to colonize target cells via the innate immune system pulmonary C-type lectin surfactant protein A.

    Science.gov (United States)

    Ragas, Aude; Roussel, Lucie; Puzo, Germain; Rivière, Michel

    2007-02-23

    Tuberculosis is still a major health problem, and understanding the mechanism by which Mycobacterium tuberculosis (Mtb) invades and colonizes its host target cells remains an important issue for the control of infection. The innate immune system C-type lectins (C-TLs), including the human pulmonary surfactant protein A (PSP-A), have been recently identified as determinant players in the early recognition of the invading pathogen and in mounting the host defense response. Although the antigenic lipoglycan mannosylated lipoarabinomannan is currently considered to be the major C-TL target on the mycobacterial surface, the recognition by some C-TLs of the only mycobacterial species composing the "Mtb complex" indicates that mannosylated lipoarabinomannan cannot account alone for this specificity. Thus, we searched for the mycobacterial molecules targeted by human PSP-A, focusing our attention on the Mtb surface glycoproteins. We developed an original functional proteomic approach based on a lectin blot assay using crude human bronchoalveolar lavage fluid as a source of physiological PSP-A. Combined with selective cell-surface protein extraction and mass spectrometry peptide mapping, this strategy allowed us to identify the Apa (alanine- and proline-rich antigenic) glycoprotein as new potential target for PSP-A. This result was supported by direct binding of PSP-A to purified Apa. Moreover, EDTA addition or deglycosylation of purified Apa samples completely abolished the interaction, demonstrating that the interaction is calcium- and mannose-dependent, as expected. Finally, we provide convincing evidence that Apa, formerly considered as mainly secreted, is associated with the cell wall for a sufficiently long time to aid in the attachment of PSP-A. Because, to date, Apa seems to be restricted to the Mtb complex strains, we propose that it may account for the selective recognition of those strains by PSP-A and other immune system C-TLs containing homologous functional

  3. PERCEPÇÃO AMBIENTAL COMO AVALIAÇÃO DA EFETIVIDADE DA APA DOS PIRENEUS – GOIÁS (DOI:10.5216/reec.V10i1.34065

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    Dayan de Loyola Ramos Garcia

    2015-07-01

    Full Text Available RESUMO: No Brasil as chamadas Unidades de Conservação (UCs, são áreas com limites territoriais estabelecidos por Lei, abrangendo recursos ambientais destinados à conservação. Partindo da preocupação com a efetividade das unidades de conversação devido a não participação da população local na gestão, nesse trabalho realizou-se um levantamento do conhecimento dos residentes de uma UC acerca dos objetivos desta e dos usos da biodiversidade e dos recursos hídricos. A UC estudada foi a Área de Proteção Ambiental dos Pireneus na intersecção dos Municípios goianos de Pirenópolis, Corumbá de Goiás e Cocalzinho de Goiás. Para coleta dos dados foram utilizados questionários, que posteriormente foram categorizados e estatisticamente analisados. Verificou-se que poucos entrevistados souberam ao certo as funcionalidades da APA dos Pireneus e que existe muita confusão conceitual por parte da população residente na APA. [Principal Contribuição] Constatou-se a importância da divulgação da APA pelo poder público e a necessidade de integração da população local no processo de gestão da unidade. ABSTRACT: In Brazil the Protected Areas calls (PAs, are areas with boundaries established by law, including environmental resources for conservation. Starting from the concern about the effectiveness of protected areas due to non participation of local people in management, in this work we carried out a survey of the knowledge of residents of a UC about the objectives of this and about the uses of biodiversity and water resources. The PA studied was the Environmental Protection Area of the Pirineus at the intersection of Municipalities of Goiás, Pirenópolis, Corumbá de Goiás and Cocalzinho of Goiás. Questionnaires were used to collect data, which were then categorized and analyzed statistically. It was found that few respondents knew what were the functions of the APA Pirineus and there is much conceptual confusion on the

  4. CONFLITOS SOCIOAMBIENTAIS NA APA BORORÉ-COLÔNIA: DOS PREEXISTENTES AOS NOVOS ASSOCIADOS AO LICENCIAMENTO AMBIENTAL DO TRECHO SUL DO RODOANEL DE SÃO PAULO

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    José Maria Bernardelli Junior

    2017-01-01

    Full Text Available This paper addresses the social and environmental conflicts in a protected landscape of sustainable use which has faced urban expansion of high social exclusion. In this scenario of both socio and environmental vulnerability, the Protected Landscape of Borore-Colonia was created, at the same time that municipal natural parks in the interior of this APA were also created as compensatory measure for the environmental licensing of the South Part of the Metropolitan Ring Road. The research question that guided the study is: What are the interference of environmental licensing of the Metropolitan Ring Road both in existing conflicts and in the generation new conflicts in the implementation of the Municipal Natural Park Itaim in the region of Borore-Colonia Protected Landscape? The objetive of this study was to analyze the conflicts in the Protected Landscape of Borore-Colonia considering both the pre-existing conflicts to the environmental licensing of the Southern Ring Road stretch and the conflicts that emerged with the creation of the park as a compensatory measure of this licensing. This research was developed as a case study having documental analysis, semi-structured interview carried out with nine social actors, and participatory research as major sources of information. The ethnographic perspective was the selected one for the conflict analysis. As a result, both socio and environmental conflicts that took place previously and simultaneously to the environmental licensing of the South Part of the Metropolitan Ring Road were analyzed with identification of the natural and social agents involved, the major actors (including the Public Power, and their power of quotas. As a conclusion, it was perceived that the pre-existing conflicts were accentuated by the new ones resulting from the licensing and the environmental impacts of the construction of the Southern Section of the Ring Road and the conduct of the Bill of the creation of the protected

  5. FORÓFITOS PREFERENCIAIS DE ORQUÍDEAS EPÍFITAS NA APA ILHA DO COMBU, BELÉM, PARÁ, BRASIL

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    Tonny David Santiago Medeiros

    2014-10-01

    Full Text Available Foi avaliada a correlação da abundância de orquídeas epífitas com o tipo de casca dos forófitos e a influência do DAP sobre a abundância e a riqueza na Área de Proteção Ambiental (APA Ilha do Combu, Belém, Pará, Brasil. O estudo foi realizado em 2,85 ha, a partir da demarcação de 114 transectos de 5 m x 50 m, onde foram mensurados todos os forófitos com DAP ≥ 20 cm e anotadas as características da casca, e identificadas as orquídeas epífitas. A correlação entre o tipo de casca dos forófitos e a abundância de orquídeas foi verificada através do número de epífitas por forófitos na espécie arbórea x, e também da razão (n.° epífitas/n.° forófitos para forófitos rugosos e não-rugosos. Os diâmetros foram categorizados em classes para verificar a influência do DAP sobre a abundância e a riqueza. Trinta e cinco espécies de forófitos (73% apresentaram casca rugosa, com destaque para Hevea brasiliensis e Carapa guianensis que foram os mais amostrados (58 e 42 e mais expressivos em número de orquídeas epífitas; a razão de epífitas por forófitos foi maior em troncos com casca não-rugosa. As classes de diâmetro 2 (31,8┤ 63,7 e 3 (63,7┤ 95,5 registraram as maiores abundâncias de orquídeas epífitas. A abundância de orquídeas epífitas é influenciada pela rugosidade da casca e correlacionada aos maiores diâmetros dos forófitos. Palavras-chave: interação, hospedeiro, orquidaceae, floresta de várzea, Amazônia. DOI: http://dx.doi.org/10.18561/2179-5746/biotaamazonia.v4n3p1-4

  6. Parâmetros nutricionais da pastagem natural em diferentes tipos de solos na APA do Ibirapuitã, Rio Grande do Sul - Brasil Nutritional parameters of natural pasture in different soils at APA of Ibirapuitã, Rio Grande do Sul - Brazil

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    Vicente Celestino Pires Silveira

    2006-12-01

    Full Text Available O desempenho de ruminantes domésticos é influenciado por fatores intrínsecos ao animal, ao alimento e pela interação entre animal e alimento. O trabalho foi realizado na Estância do 28, pertencente à Fundação Maronna, Alegrete - RS, dentro da APA do Ibirapuitã. Para representar o fator solo, foram escolhidos os três tipos predominantes da APA do Ibirapuitã: Basalto Superficial, Basalto Profundo e Arenito. As amostras da pastagem natural foram retiradas por simulação de pastejo, através de coleta manual. Os parâmetros nutricionais avaliados foram: proteína bruta, fibra em detergente neutro e taxa de degradação da matéria seca. A forragem da pastagem natural oriunda do solo Basalto Superficial apresentou diferença significativa (PIntrinsic animal and food factors and the interaction between them influence the performance of domestic ruminants. This study was done at Estância do 28, property of the Maronna Foundation, Alegrete - RS, inside the Ibirapuitã Area of Environmental Protection. In order to represent soil as a factor, the three main soil types were chosen: Superficial Basalt, Deep Basalt and Sandy. Hand plucking methods were used to obtain samples of natural pasture. Nutritional parameters considered were crude protein, neutral detergent fiber and dry matter degradation rate. The forage from natural pasture of the Superficial Basalt presented significant difference (P<0.05 in crude protein rates over the other two types of soil, which did not differ amongst themselves. The highest rate of neutral detergent fibre (84.54% was obtained in pasture originated from Sandy soil, in relation to Superficial and Deep Basalt, with values of 74.53% and 77.98%, respectively. There was also a significant difference in the degradation rate of dry matter (P<0.05. Sandy soil pasture presented an intermediate degradation value (3.61% h-1, not differing from other soils. The forage from natural pastures present similar degradation rates

  7. Reservations about the conclusions of the interdivisional (APA Divisions 12 & 29) task force on evidence-based therapy relationships: what do we know, what don't we know?

    Science.gov (United States)

    Kazantzis, Nikolaos; Cronin, Timothy J; Norton, Peter J; Lai, Jerry; Hofmann, Stefan G

    2015-05-01

    We offer a critical and constructive appraisal of the conclusions provided by the Interdivisional (American Psychological Association [APA] Divisions 12 & 29) Task Force on Evidence-Based Therapy Relationships. We highlight problems in overlapping terminology and definitions, as well as problems in the conduct of its meta-analyses (i.e., duplication of studies between reviews, inappropriate study inclusion, and use of measures of specific constructs for the calculation of effects for multiple relationship elements). On this basis, we express reservation about the conclusions offered by the APA Task Force. This special issue explores whether there are other therapeutic relationship elements that warrant consideration and further study. We were particularly interested in those elements that showed promise based on empirical or theoretical grounds, and in each article, we asked for an account of how the case formulation would guide the methods of adaptation for each individual client, and how the element would contribute to clinically relevant changes. © 2015 Wiley Periodicals, Inc.

  8. Referenciación bibliográfica en ciencias de la educación: criterios de la APA y un ejemplo de gestión a través del programa END-NOTE

    OpenAIRE

    Cubo Delgado, Sixto; González Gómez, José Juan; González Chaves, Silvia

    2004-01-01

    Whith this paper we aim at offering a global picture of the criteria of bibliographical reference that is more frequently used in the educational field. We specially deal with the criteria proposed by the American Psychological Association (APA) for being the ones more used in this context.After the exposition fo the above mentioned criteria and the reference to several works as example, we propose some procedures to index the documents obtained by electronic resources, emphasizing the intern...

  9. Aberrant gonadotropin-releasing hormone receptor (GnRHR) expression and its regulation of CYP11B2 expression and aldosterone production in adrenal aldosterone-producing adenoma (APA).

    Science.gov (United States)

    Nakamura, Yasuhiro; Hattangady, Namita G; Ye, Ping; Satoh, Fumitoshi; Morimoto, Ryo; Ito-Saito, Takako; Sugawara, Akira; Ohba, Koji; Takahashi, Kazuhiro; Rainey, William E; Sasano, Hironobu

    2014-03-25

    Aberrant expression of gonadotropin-releasing hormone receptor (GnRHR) has been reported in human adrenal tissues including aldosterone-producing adenoma (APA). However, the details of its expression and functional role in adrenals are still not clear. In this study, quantitative RT-PCR analysis revealed the mean level of GnRHR mRNA was significantly higher in APAs than in human normal adrenal (NA) (P=0.004). GnRHR protein expression was detected in human NA and neoplastic adrenal tissues. In H295R cells transfected with GnRHR, treatment with GnRH resulted in a concentration-dependent increase in CYP11B2 reporter activity. Chronic activation of GnRHR with GnRH (100nM), in a cell line with doxycycline-inducible GnRHR (H295R-TR/GnRHR), increased CYP11B2 expression and aldosterone production. These agonistic effects were inhibited by blockers for the calcium signaling pathway, KN93 and calmidazolium. These results suggest GnRH, through heterotopic expression of its receptor, may be a potential regulator of CYP11B2 expression levels in some cases of APA. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  10. Predação oportunista de Artibeus planirostris (Spix, 1823 e Carollia perspicillata (Linnaeus, 1758 (Chiroptera, Phyllostomidae por marsupiais e anuro na APA do Rio Curiaú, Amapá, Brasil Opportunistic predation of Artibeus planirostris (Spix, 1823 and Carollia perspicillata (Linnaeus, 1758 (Chiroptera, Phyllostomidae by marsupials and anuran in the APA do Rio Curiaú, Amapá State, Brazil

    Directory of Open Access Journals (Sweden)

    Isai Jorge de Castro

    2011-03-01

    Full Text Available Durante estudos com morcegos em floresta de várzea na APA do Rio Curiaú, Amapá, Brasil, observamos três casos de predações oportunistas de morcegos frugívoros capturados em redes de neblina. Duas destas predações ocorreram por marsupiais e uma por anuro. Artibeus planirostris (Spix, 1823 (Chiroptera, Phyllostomidae foi predado por Didelphis marsupialis Linnaeus, 1758 e Philander opossum (Linnaeus, 1758 (Didelphimorphia, Didelphidae. Carollia perspicillata (Linnaeus, 1758 (Chiroptera, Phyllostomidae foi predado por Leptodactylus pentadactylus (Laurenti, 1768 (Anura, Leptodactylidae. A vocalização dos morcegos provavelmente atraiu os marsupiais para a rede, onde estes os predaram aproveitando que estavam presos. Este tipo de interação pode ocorrer naturalmente, no entanto, com maior dificuldade de registro.We observed three occasional predations of bats captured in mist nets by marsupials and a frog during studies in a várzea forest in the Amapá state. Artibeus planirostris (Spix, 1823 (Chiroptera, Phyllostomidae was preyed upon by Didelphis marsupialis Linnaeus, 1758 and Philander opossum (Linnaeus, 1758 (Didelphimorphia, Didelphidae. Carollia perspicillata (Linnaeus, 1758 (Chiroptera, Phyllostomidae was preyed on by Leptodactylus pentadactylus (Laurenti, 1768 (Anura, Leptodactylidae. The bats vocalizations probably attracted the marsupials and a frog to the mist nets where they preyed. This interaction form can occur naturally, however, are more difficult to observed.

  11. Análise quantitativa do processo de erosão/deposição nas falésias da APA Tambaba e sua ocupação nos limites da APP

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    Thaís Regina Benevides Trigueiro Aranha

    2013-08-01

    Full Text Available O litoral brasileiro é banhado pelo Oceano Atlântico e composto por diversas paisagens ao longo da costa. Entre elas encontram-se as falésias, que, por sua beleza, atraem a exploração turística o que, muitas vezes, compromete seu equilíbrio. Com a finalidade de proteger o meio ambiente das ações antrópicas, o poder público vem criando áreas para preservar e/ou conservar o meio ambiente, entre elas existem as APA e as APP. O objetivo do presente trabalho foi analisar a variabilidade espaço-temporal da linha de ruptura do relevo, na borda das falésias da APA Tambaba, entre os anos de 1985 e 2012; e identificar a existência de edificações dentro da APP no ano de 2012. Para tanto, foram utilizadas imagens do satélite Quickbird de 2012, do satélite IKONOS II de 2005 e fotos aéreas de 1985 para delimitação das linhas das falésias; o DSAS, que é uma extensão gratuita do ArcGIS, para obtenção de taxas de variação da linha de ruptura do relevo; e o software ArcGIS para delimitação e análise das APP. Como resultados, foram identificadas variações no movimento das linhas estudadas, tanto para erosão como para deposição nas falésias da APA Tambaba. No maior trecho da APA obteve-se uma média de -0,17m/ano para erosão e de 0,49m/ano para deposição, já no menor trecho a média de erosão foi -0,38m/ano e de deposição 0,14m/ano. Foi comprovada a existência de edificações irregulares correspondente a 22.818,91 m², o que equivale a aproximadamente 3% da área total da APP.

  12. Comunicação ambiental: estratégias de mobilização socioparticipativa para educação, informação e integração da rede socioambiental APA SUL RMBH

    Directory of Open Access Journals (Sweden)

    Miguel Ângelo Andrade

    2010-01-01

    Full Text Available This article aims at introducing and analyzing communication models used in the socio-environmental network APA SUL RMBH, an environmentally sensitive area in which polemic issues and economicinterests are involved. These models provide inter-sectorial, participative, egalitarian and dynamic dialogues and information in order to put emphasis on the mobilization that characterizes the communicative process. The definition of common purposes, social actors and their roles, the active participation of all members of the community as well as the planning for more efficiency in the process reveal strategies of mobilization which structure themselves “with” and not “for” society. In this context, the usufruct and the consolidation of effective communication tools like, for example, permanent forums for debates, informational booklet, social research, training of local staff within a virtual and high-tech structuralmodel – Portal (or Site of the socio-environmental network APA SUL RMBH – have become a foundation for the convocation of common purposes and the establishment of social networks. Thus, the weaving and the crossing of these relationships outline an interconnected set of complementary factorsthat govern social mobilization in this socio-biodiversity area.

  13. Efetividade sócio-ambiental da APA Carste de Lagoa Santa-MG: uma avaliação a partir de suas ferramentas de planejamento e gestão

    OpenAIRE

    Luciana de Resende Alt

    2008-01-01

    O objetivo principal desta dissertação é avaliar a efetividade sócio-ambiental da Área de Proteção Ambiental-AP A Carste de Lagoa Santa por meio da análise de seus principais instrumentos de planejamento e gestão. Localizada a cerca de 40 km a norte de Belo Horizonte, essa APA possui área de 35.600 ha e abrange parcialmente os municípios de Lagoa Santa, Pedro Leopoldo, Matozinhos e Funilândia e, integralmente, o de Confins. Criada em 1990, abriga rico patrimônio - cavernas, sítios arqueológic...

  14. Scale-up from shake flasks to bioreactor, based on power input and Streptomyces lividans morphology, for the production of recombinant APA (45/47 kDa protein) from Mycobacterium tuberculosis.

    Science.gov (United States)

    Gamboa-Suasnavart, Ramsés A; Marín-Palacio, Luz D; Martínez-Sotelo, José A; Espitia, Clara; Servín-González, Luis; Valdez-Cruz, Norma A; Trujillo-Roldán, Mauricio A

    2013-08-01

    Culture conditions in shake flasks affect filamentous Streptomyces lividans morphology, as well the productivity and O-mannosylation of recombinant Ala-Pro-rich O-glycoprotein (known as the 45/47 kDa or APA antigen) from Mycobacterium tuberculosis. In order to scale up from previous reported shake flasks to bioreactor, data from the literature on the effect of agitation on morphology of Streptomyces strains were used to obtain gassed volumetric power input values that can be used to obtain a morphology of S. lividans in bioreactor similar to the morphology previously reported in coiled/baffled shake flasks by our group. Morphology of S. lividans was successfully scaled-up, obtaining similar mycelial sizes in both scales with diameters of 0.21 ± 0.09 mm in baffled and coiled shake flasks, and 0.15 ± 0.01 mm in the bioreactor. Moreover, the specific growth rate was successfully scaled up (0.09 ± 0.02 and 0.12 ± 0.01 h(-1), for bioreactors and flasks, respectively), and the recombinant protein productivity measured by densitometry, as well. More interestingly, the quality of the recombinant glycoprotein measured as the amount of mannoses attached to the C-terminal of APA was also scaled- up; with up to five mannose residues in cultures carried out in shake flasks; and six in the bioreactor. However, final biomass concentration was not similar, indicating that although the process can be scaled-up using the power input, others factors like oxygen transfer rate, tip speed or energy dissipation/circulation function can be an influence on bacterial metabolism.

  15. POLA PENDIDIKAN KITA, APA YANG SALAH

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    Alpiyanto Alpiyanto

    2012-06-01

    Full Text Available AbstractIdeals to the intellectual life of the nation by order of value as thefoundation of ethics and moral domains of intelligence and skill has beendisoriented. It can be seen from the culture of corruption that stillplagued the country, beating punishment of journalists that was hitby students of SMAN 6 Jakarta, clashes among students in Lampung, clashes among residents in different regions and the church bombing inSolo. Therefore, this study wanted to find out what went wrong to educationthat has been implemented so far. This study is a case study of thepatterns which are applied during this study. The study results showed that theeducation that has been implemented so far seems to be concerned with the logicrather than feelings (language of heart so it is suggested that it is important to educate the heart rather than logic.Keywords: educate, by heart, logic

  16. APA Citation Style (6th edition)

    OpenAIRE

    2013-01-01

    ARP-AA-12-003 Acquisition Research Handbook Series This handbook is one of a series of four produced for the Acquisition Research Program (ARP) at the Naval Postgraduate School. The purpose of the ARP Handbook Series is to provide helpful information in a user-friendly format to assist graduate students and others in improving their research and writing skills.

  17. Citing Legal Material in APA Journals.

    Science.gov (United States)

    Osborne, Allan G., Jr.

    1992-01-01

    Guidelines are offered to authors on the correct citation format for legal references, including statutes and regulations, court decisions, and law review articles. Standards are based on those published by the Harvard Law Review Association and the American Psychological Association. (DB)

  18. Análise da riqueza da fauna de Braconidae (Hymenoptera, Ichneumonoidea em remanescentes naturais da Área de Proteção Ambiental (APA de Descalvado, SP

    Directory of Open Access Journals (Sweden)

    Cirelli Kátia Resende Netto

    2003-01-01

    Full Text Available Analysis of the Braconidae (Hymenoptera: Ichneumonoidea fauna richness in natural remnants of the Área de Proteção Ambiental (APA of Descalvado, SP. A survey of the Braconidae fauna on fragmentary natural environments at northeast São Paulo State was conducted using Malaise traps installed in five sites of Área de Proteção Ambiental of Descalvado. A total of 2,262 specimens, representing 22 subfamilies and 94 genera, was sampled throughout a period of sixteen months (from May, 1999 to August, 2000. Biological data were obtained from current literature and behavior patterns of host utilization for the studied fauna, mainly Braconidae which have been successful in control of agricultural insect pests. Statistical analyses indicated that the asymptote of the genera richness has been approached using this sampling method. This is the most complete survey yet available from natural fragmentary areas of the Descalvado Braconidae fauna. Patterns of distribution and richness of the Braconidae genera were established. Cluster Analysis was adopted taking as attribute the number of Braconidae genera.

  19. Aspectos do licenciamento ambiental da carcinicultura na APA do Delta do Parnaíba Aspects of environmental licensing for carciniculture in EPA of the Delta of Parnaíba River

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    Hamilton Gondim de Alencar Araripe

    2006-12-01

    Full Text Available O presente trabalho tem como foco uma análise do valor do licenciamento ambiental da carcinicultura na APA do Delta do Parnaíba. Realizou-se visitas técnicas a todos empreendimentos instalados até o primeiro semestre de 2004, levantou-se a legislação pertinente, avaliou-se estudos ambientais e relatórios de vistorias técnicas realizadas pelo IBAMA. Concluiu-se que o enquadramento feito pelo IBAMA no processo de licenciamento do que seja área de preservação permanente (APP no manguezal é o ponto crítico para a atividade de carcinicultura.The present research examines the environmental matter in the Environmental Protection Area (EPA of the Delta of the Parnaíba River, focusing on the ambient licensing value. Technical visits to all companies installed in the area until the first semester of 2004 and non-structured interviews were carried out; the existing legislation was raised; and the environmental studies and reports of technical inspections performed by IBAMA were evaluated. The conclusion was that the adjustment made by IBAMA in the ambient licensing process of what is an Area of Permanent Preservation (APP in the mangrove is the critical point to the carciniculture activity.

  20. A apropriação social do espaço como fator de urbanização na dinâmica das sociedades modernas: o caso da APA da Fazendinha

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    Olavo Fagundes da Silva

    2010-07-01

    Full Text Available Normal 0 21 false false false MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabela normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} O trabalho faz uma reflexão sobre a singularidade da urbanização a partir da apropriação social dos espaços urbanos no mundo moderno, toma-se como referencia o processo de apropriação social e urbanização na Área de Proteção Ambiental da Fazendinha situada entre os municípios de Macapá e Santana no estado do Amapá. Procurou-se analisar as nuances do processo de urbanização que mescla a instalação de elementos da dinâmica capitalista nas cidades com as transformações engendradas pelos menos abastados. Esse aparente choque entre o moderno e objetos que marcam os traços culturais do povo da região Amazônica em suas cidades médias e grandes está estampado em arranjos espaciais que configuram o urbano como resultado da apropriação social do espaço. Estes arranjos foram objeto do estudo da apropriação social na APA da Fazendinha realizado em incursões ao local em 2007 através de entrevistas e mapeamento físico-ambiental utilizando aparelho receptor GPS e técnicas de geoprocessamento. O estudo constatou-se que a apropriação social da APA da Fazendinha resultou no processo de urbanização da unidade de conservação por uma população de baixa renda, que imprimiu no local, traços de suas características culturais, como a construção de palafitas na margem do Igarapé da Fortaleza e uma dinamização econômica baseada na informalidade, mas fortemente ligada a atividades tradicionais da região como a pesca e a construção de pequenas

  1. Sphagnum (velvet species used by rural communities at the Guaratuba EPA, Paraná State, Brazil=Espécies de Sphagnum (veludo utilizadas pelas comunidades rurais da APA de Guaratuba, Estado do Paraná, Brasil

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    Suelen Elizabeth Bordignon

    2012-04-01

    Full Text Available The results of a survey of Sphagnum used by the Descoberto and Empanturrado rural communities (Guaratuba municipality and Guaratuba Environmental Protected Area – EPA are presented. The analysis was based on fresh material collected in different harvesting areas. Five species were recorded: S. capillifolium (Ehrh. Hedw., S. cuspidatum Ehrh. ex Hoffm., S. erythrocalyx Hampe, S. perichaetiale Hampe and S. recurvum P. Beauv.. All of them are native species that grow spontaneously in that region and are intensively harvested by the local community. A key is presented to differentiate the species, and the botanical description, common names, geographic distribution and illustrations for each species are included.Apresenta-se resultado de levantamento das espécies de Sphagnum L. utilizadas pelas comunidades rurais de Descoberto e Empanturrado (Município de Guaratuba, APA de Guaratuba, Paraná. A partir de coletas e identificação de material botânico nos locais de extrativismo, foram registradas cinco espécies: S. capillifolium (Ehrh. Hedw., S. cuspidatum Ehrh. ex Hoffm., S. erythrocalyx Hampe, S. perichaetiale Hampe e S. recurvum P. Beauv.. Todas com ocorrência natural na região de estudo e submetidas a intenso extrativismo pela demanda do segmento floricultor. Incluem-se chave dicotômica para identificação, descrições, caracterização do hábitat, distribuição geográfica e ilustrações para cada espécie identificada.

  2. INFLUÊNCIA DOS FATORES GEOLÓGICOS, GEOMORFOLÓGICOS E ANTRÓPICOS DA PRODUÇÃO DE FLUXO DE BASE EM PEQUENAS BACIAS HIDROGRÁFICAS NA APA CACHOEIRA DAS ANDORINHAS, OURO PRETO (MG

    Directory of Open Access Journals (Sweden)

    Josefa Clara Monteiro

    2014-08-01

    Full Text Available Neste trabalho objetivou-se estabelecer a influência da geologia, geomorfologia e uso e ocupação do solo no potencial hídrico de pequenas bacias hidrográficas situadas na Área de Proteção Ambiental Estadual da Cachoeira das Andorinhas (APA/CA. Foram selecionados três pares de bacias, cada par com condições geológicas e geomorfológicas semelhantes, mas com graus distintos de interferência antrópica. Utilizando-se dados de chuva e vazão, obtidos durante um ano hidrológico, estabeleceram-se os regimes pluviométricos e fluviométricos e determinaram-se alguns parâmetros hidrológicos, como o fluxo de base pela técnica smoothed mínima e o coeficiente de recessão (α pela técnica matching strip. A análise conjugada destes parâmetros, de índices morfométricos e de dados físico-químicos das águas indicam que as bacias em áreas de relevo mais suave tendem a apresentar menores coeficientes de recessão e maiores volumes de fluxo de base. Portanto, nestas áreas o potencial hídrico é maior, já que a vazão das drenagens se mantém por mais tempo na estação seca. O relevo mais suave, com solo mais espesso e maior tempo de trânsito das águas subterrâneas, também justificam as águas mais redutoras e com maiores condutividades elétricas. Os dados também sugerem que as bacias da área com maiores proporções de florestas tendem a apresentar menores fluxos de base por conta das maiores taxas de evapotranspiração. Os métodos aplicados se mostraram adequados para caracterizar o regime hídrico de pequenas bacias hidrográficas e podem ser importantes para a gestão de recursos hídricos.

  3. Trajetórias do Jaguary - unidades de conservação, percepção ambiental e turismo: um estudo na APA do Sistema Cantareira, São Paulo Trajectories of the Jaguary conservation areas, environmental perception and tourism a study in the Cantareira system environmental protected area, São Paulo

    Directory of Open Access Journals (Sweden)

    João Luiz Hoeffel

    2008-06-01

    Full Text Available A Área de Proteção Ambiental Cantareira (APA Cantareira tem passado por diversas transformações, associadas à expansão urbana e turística. Observa-se, nesta pesquisa, que os grupos sociais atuantes nessa região apresentam diferentes perspectivas sobre meio ambiente e desenvolvimento, o que tem gerado conflitos de uso pelos recursos naturais, e que não existem planos regionais que apontem soluções efetivas para os problemas socioambientais em curso.The Cantareira Environmentally Protected Area (EPA Cantareira has been undergoing several transformations due to the growth of urban areas and tourism. The present piece of research points out that the active social groups in this region have different perspectives to the environment and development. This leads to conflicts in the use of natural resources and there are no regional plans suggesting effective solutions for the identified social and environmental problems.

  4. RAP workshop : Buda-TxAPA, Texas, August 27, 2009.

    Science.gov (United States)

    2009-08-27

    Presentation Outline : RAP overview : RAP stockpile survey: state of practice : RAP processing and RAP variability : RAP characterization : RAP mix design : Field performance of Texas high RAP test sections

  5. How to Use Current Medical Literature and APA Format Style.

    Science.gov (United States)

    Peek, Robin

    Directives and guidance in obtaining current medical literature are provided in this publication with special emphasis given to locating material in the Portland, Oregon area. The uses and types of periodical indexes are identified and periodical index citation examples are indicated. Explanations are offered on: (1) how to conduct an effective…

  6. Violence against Teachers: Case Studies from the APA Task Force

    Science.gov (United States)

    Reddy, Linda A.; Espelage, Dorothy; McMahon, Susan D.; Anderman, Eric M.; Lane, Kathleen Lynne; Brown, Veda Evanell; Reynolds, Cecil R.; Jones, Abraham; Kanrich, Jaclyn

    2013-01-01

    Violence directed toward teachers has been understudied despite significant media and empirical investigation on school violence, such as student-to-student victimization and bullying. To date, there are relatively few published studies scattered across many countries. To address this void, the American Psychological Association, in collaboration…

  7. Forging ahead: the 2003 APA Division 30 definition of hypnosis.

    Science.gov (United States)

    Green, Joseph P; Barabasz, Arreed F; Barrett, Deirdre; Montgomery, Guy H

    2005-07-01

    The article describes the rationale for and the process of developing a new definition of hypnosis by the Society of Psychological Hypnosis, Division 30 of the American Psychological Association. Both theoretical and practical implications led to the production of the definition, which is targeted toward informing clinicians, researchers, and the lay public alike. The definition is presented at the conclusion of the article.

  8. Critical Pedagogy and APA: A Resonant (and Timely) Interdisciplinary Blend.

    Science.gov (United States)

    Connolly, Maureen; Harvey, William J

    2018-04-12

    Critical pedagogy owes much of its emergence, development, and ongoing relevance to the work of Paulo Freire whose legacy remains relevant for a next generation of scholars who seek to explore issues of inclusion, oppression, social justice, and authentic expression. An interdisciplinary dialogue between critical pedagogy and adapted physical activity is timely, appropriate, and should focus on complex profiles of neurodiversity, mental illness, and mental health, with emphasis on pedagogic practices of practitioners in service delivery and teacher educators who prepare them for professional practice. A case-based scenario approach is used to present practitioner and teacher educator practices. Concrete examples are provided for analyzing and understanding deeper issues and challenges related to neurodiversity in a variety of embodied dimensions in educational and activity contexts. We work with Szostak's approach to interdisciplinary research and model an analysis strategy that integrates and applies the methodological features of interdisciplinarity, adapted physical activity, and critical pedagogy.

  9. Asphalt mix characterization using dynamic modulus and APA testing.

    Science.gov (United States)

    2005-11-01

    final report summarizes two research efforts related to asphalt mix characterization: dynamic modulus and Asphalt Pavement Analyzer testing. One phase of the research consisted of a laboratory-based evaluation of dynamic modulus of Oregon dense-grade...

  10. Putting the APA "Publication Manual" in Context. Commentary.

    Science.gov (United States)

    Russo, Nancy Felipe

    1999-01-01

    Explores feminist criticism of the "Publications Manual" of the American Psychological Association and the ways in which feminist researchers have negotiated changes in the language of this style guide. (SLD)

  11. Preparing Special Education Research Articles in APA Style.

    Science.gov (United States)

    Algozzine, Bob; Spooner, Fred; Karvonen, Meagan

    2002-01-01

    This article addresses key considerations in preparing special education research articles for submission to professional journals in which the preferred style guide is the "Publication Manual of the American Psychological Association." The guidelines are drawn from special education literature, from editors, and from authors experienced in…

  12. Writing in APA Style: Faculty Perspectives of Competence and Importance

    Science.gov (United States)

    Landrum, R. Eric

    2013-01-01

    A US sample (N = 360) of psychology educators assessed 73 writing skills and competencies with regard to (a) the importance of each and (b) the typical performance of the top half of local psychology majors. An analysis of gap scores yielded results showing that specific skills, such as supporting claims with citations and proofreading ability,…

  13. Tipologia de frutos e síndromes de dispersão de um fragmento de Cerrado sensu stricto da APA do Gama e Cabeça de Veado e montagem de Coleção Didática de frutos – Carpoteca - doi: 10.5102/ucs.v9i1.1385

    Directory of Open Access Journals (Sweden)

    Carolina Cátia Schaffer

    2011-07-01

    Full Text Available Com o objetivo de realizar um levantamento tipológico de frutos e síndromes de dispersão de um fragmento de Cerrado sensu stricto, e montar uma carpoteca, o presente trabalho partiu da premissa de que o Cerrado apresenta alta diversidade de frutos e estratégias de dispersão. Os frutos foram coletados na APA do Gama e Cabeça de Veado (Brasília-DF, entre os meses de agosto de 2009 a maio de 2010. A coleta foi feita pelo método de caminhamento com busca ativa por espécimes maduros. Os frutos foram classificados de acordo com a consistência, deiscência e as síndromes de dispersão, e divididos em grupos, tipos e subtipos. Foram coletados 79 frutos, sendo 70 frutos simples, 7 múltiplos e 2 compostos; 43 deiscentes e 36 indeiscentes; 53 secos e 26 carnosos. Anemocoria foi a síndrome de dispersão prevalecente. A diversidade florística encontrada no fragmento garantiu elevada variabilidade de formas de frutos para a carpoteca.

  14. Levantamento florístico e sua distribuição diamétrica da vegetação de um cerrado sensu stricto e de um fragmento de floresta de galeria no ribeirão Dois Irmãos na APA de Cafuringa, DF, Brasil

    Directory of Open Access Journals (Sweden)

    José Elias de Paula

    2009-06-01

    Full Text Available http://dx.doi.org/10.5007/2175-7925.2009v22n3p35 Foram identificadas todas as espécies vegetais ocorrentes em uma área de 2.500m² de cerrado sensu stricto e de 5.000m² de um fragmento de uma floresta de galeria do ribeirão Dois Irmãos na APA de Cafuringa, localizada na região norte do Distrito Federal, próximo à divisa do Estado de Goiás, nas coordenadas geográficas 15º30’19”S e 48º06’18”W. Foram medidos os diâmetros de todos os indivíduos arbóreos com diâmetro à altura do peito (DAP a partir de 5cm, tanto do cerrado sensu stricto como do fragmento da floresta de galeria. A composição florística do cerrado sensu stricto ficou composta por 100 indivíduos arbóreos distribuídos em 25 espécies, e da floresta de galeria por 155 árvores distribuídas em 50 espécies. A regeneração natural constituída por indivíduos de hábito arbóreo com DAP inferior a 5cm, no cerrado sensu stricto foi de 211 indivíduos distribuídos em 38 espécies, e na floresta de galeria foram 287 indivíduos, distribuídos em 55 espécies. A área basal ocupada pelos componentes arbóreos foi de 3,40m2.ha-1 na área do cerrado sensu stricto e 5,08m2.ha-1 na floresta de galeria. A curva da distribuição diamétrica de ambas as comunidades ajustada pela equação de Meyer apresentou a tendência típica do “J” invertido e mostrou forte intervenção antrópica nas classes de 11 a 17cm.

  15. Teaching Statistics in APA-Accredited Doctoral Programs in Clinical and Counseling Psychology: A Syllabi Review

    Science.gov (United States)

    Ord, Anna S.; Ripley, Jennifer S.; Hook, Joshua; Erspamer, Tiffany

    2016-01-01

    Although statistical methods and research design are crucial areas of competency for psychologists, few studies explore how statistics are taught across doctoral programs in psychology in the United States. The present study examined 153 American Psychological Association-accredited doctoral programs in clinical and counseling psychology and aimed…

  16. ECOTURISMO, GESTÃO PARTICIPATIVA E DILEMAS LOCAIS: UMA ANÁLISE NA APA DO PURAQUEQUARA

    Directory of Open Access Journals (Sweden)

    Fagno Oliveira

    2011-05-01

    Full Text Available Este artigo apresenta uma análise do contexto da gestão participativa de comunidades locais em uma área de uso sustentável prescrita no Sistema Nacional de Unidades de Conservação da Natureza (SNUC, 2000, no ato de criação, implementação e gestão dessas áreas. A pesquisa foi desenvolvida na cidade de Manaus, estado do Amazonas, em três comunidades ribeirinhas localizadas em uma Área de Proteção Ambiental em processo de implementação. A metodologia utilizada consistiu em revisão bibliográfica e utilização da técnica de observação direta intensiva. As comunidades avaliadas foram: Igarapé da Floresta, Santa Luzia e São Francisco do Mainã localizadas no rio Puraquequara. Foram entrevistadas 62 pessoas, realizando levantamento sobre “unidades de conservação, turismo, problemas locais e atuação do governo”. Os resultados obtidos apontam a necessidade de atuação do governo municipal e estadual, na execução de estratégias e planos para o conhecimento sobre áreas protegidas, conservação ambiental e participação local.

  17. Of Course: Prerequisite Courses for Admission into APA-Accredited Clinical and Counseling Psychology Programs

    Science.gov (United States)

    Norcross, John C.; Sayette, Michael A.; Stratigis, Katerina Y.; Zimmerman, Barrett E.

    2014-01-01

    Students often inquire about which psychology courses to complete in preparation for graduate school. This study provides data that enable students and their advisors to make research-informed decisions. We surveyed the directors of the 304 American Psychological Association-accredited doctoral programs in clinical and counseling psychology (97%…

  18. Training in Strength-Based Intervention and Assessment Methodologies in APA-Accredited Psychology Programs

    Science.gov (United States)

    Nichols, Kayla; Graves, Scott L., Jr.

    2018-01-01

    The importance of identifying and building on individual strengths has been a key component of many psychoeducational theories and modalities focused on developing interventions. However, program training in this growing area is not well known. As such, this is the first study designed to ascertain the American Psychological Association-accredited…

  19. Advancing Research and Practice: The Revised APA Division 30 Definition of Hypnosis.

    Science.gov (United States)

    Elkins, Gary R; Barabasz, Arreed F; Council, James R; Spiegel, David

    2015-04-01

    This article describes the history, rationale, and guidelines for developing a new definition of hypnosis by the Society of Psychological Hypnosis, Division 30 of the American Psychological Association. The definition was developed with the aim of being concise, being heuristic, and allowing for alternative theories of the mechanisms (to be determined in empirical scientific study). The definition of hypnosis is presented as well as definitions of the following related terms: hypnotic induction, hypnotizability, and hypnotherapy. The implications for advancing research and practice are discussed. The definitions are presented within the article.

  20. Konvergensi Standar Laporan Keuangan ke Standar Pelaporan Keuangan Internasional, Apa dan Bagaimana

    Directory of Open Access Journals (Sweden)

    Heri Sukendar W.

    2009-03-01

    Full Text Available This research aims to explain development of the convergence of financial accounting standards under IFRS outline being implemented in Indonesia. In the early part, background of the convergence from Indonesian GAAP to IFRS is discussed, both economically and politically to the latest developments in the convergence to IFRS at the present. Furthermore, it is also described the basic framework of the IFRS, which is the fundamental preparation of financial report under IFRS. At the end, this research will explain the impact of IFRS convergence on accounting and financial reporting systems, the impact of IFRS on business and the differences between IFRS and tax principles.

  1. Structural Sizing of the EDIN0620 Body Components Using the APAS Structural Synthesis Computer Program

    Science.gov (United States)

    Nolte, W. E.

    1976-01-01

    The use of a structural synthesis computer program to design components for a heavy lift launch vehicle is defined. A loads program was used to determine the vehicle shears, bending moments, and axial loads at two design loading conditions. A comparison was made between results from the structures program and the results of a weight estimating program which used historical data in determining component weights.

  2. Application of The APA Practice Guidelines on Suicide to Clinical Practice.

    Science.gov (United States)

    Jacobs, Douglas G; Brewer, Margaret L

    2006-06-01

    This article presents charts from The American Psychiatric Association Practice Guideline for the Assessment and Treatment of Patients with Suicidal Behaviors, part of the Practice Guidelines for the Treatment of Psychiatric Disorders Compendium, and a summary of the assessment information in a format that can be used in routine clinical practice. Four steps in the assessment process are presented: the use of a thorough psychiatric examination to obtain information about the patient's current presentation, history, diagnosis, and to recognize suicide risk factors therein; the necessity of asking very specific questions about suicidal ideation, intent, plans, and attempts; the process of making an estimation of the patient's level of suicide risk is explained; and the use of modifiable risk and protective factors as the basis for treatment planning is demonstrated. Case reports are used to clarify use of each step in this process.

  3. The Use of Informational Formats to Implement APA Ethical Principles in Collecting Classroom Data.

    Science.gov (United States)

    Dolly, John P.; And Others

    1978-01-01

    Providing more information about experimental studies than required under the ethical principles formulated by the American Psychological Association can result in data bias on a specific task; overall, however, the implementation of ethical principles has little effect on data collected in classroom settings. (RL)

  4. An overview of the major changes in the 2002 APA Ethics Code.

    Science.gov (United States)

    Knapp, Samuel; VandeCreek, Leon

    2003-06-01

    This article summarizes the major changes that were made to the 2002 Ethical Principles and Code of Conduct of the American Psychological Association. The 2002 Ethics Code retains the general format of the 1992 Ethics Code and does not radically alter the obligations of psychologists. One goal of the Ethics Committee Task Force was to reduce the potential of the Ethics Code to be used to unnecessarily punish psychologists. In addition, the revised Ethics Code expresses greater sensitivity to the needs of cultural and linguistic minorities and students. Shortcomings of the 2002 Ethics Code are discussed.

  5. DIVERSIDADE DE BROMELIACEAE NA APA SANTUÁRIO ECOLÓGICO DA PEDRA BRANCA, CALDAS, MG

    Directory of Open Access Journals (Sweden)

    Amália Eugênia Matavelli Rosa

    2014-10-01

    Full Text Available A Área de Proteção Ambiental Santuário Ecológico da Pedra Branca localiza-se no município de Caldas, sul de Minas Gerais. Nos seus 119 km2, a altitude é sempre superior a 1000m, chegando a 1760m no seu ponto culminante. O presente estudo objetiva o conhecimento da diversidade de Bromeliaceae, bem como sua distribuição por fisionomias vegetais e um diagnóstico sobre o estado de conservação da área. Durante os meses de julho/2009 e dezembro/2010 foram realizadas coletas abrangendo as diversas fisionomias vegetais desta unidade de conservação. Foram catalogadas 19 espécies de Bromeliaceae distribuídas por 5 fisionomias vegetais. A maior diversidade de Bromeliaceae ocorre ao longo da Serra da Pedra Branca, seja pela integridade da flora ou pela combinação entre altitude, clima e relevo que propiciam o surgimento de um mosaico de fisionomias.

  6. Mencegah Korupsi di Pengadaan Barang dan Jasa : Apa yang sudah dan yang masih harus dilakukan?

    NARCIS (Netherlands)

    Wibowo, R.A.

    2015-01-01

    This paper aims to explore and to give appreciation for the efforts which have been done by the Indonesian government to prevent corruption in public procurement, such as: (i) designing procurement organisational structure which enables more checks and balances on the system; and (ii) designing the

  7. Quantitative Statements in Standards of Three Accrediting Bodies: APA, CACREP, and CSWE.

    Science.gov (United States)

    Peterson, Marla P.; Turner, Janet

    The accreditation manual of the Council for Accrediation of Counseling and Related Education Programs (CACREP) contains a statement that, whenever possible, criteria for assessing standards should be qualitative rather than quantitative. The study reported in this paper was conducted to gather baseline data on the extent to which accrediting…

  8. Guidelines for Nonsexist Language in APA Journals: Publication Manual Change Sheet 2

    Science.gov (United States)

    American Psychologist, 1977

    1977-01-01

    This second change sheet for its publication manual states the American Psychologist Association's policy on sexist language in its journals offers some general principles for journal authors to consider, and suggests some ways to avoid sexist language. (Author)

  9. Gentlemanly Orthodoxy: Critical Race Feminism, Whiteness Theory, and the APA Manual

    Science.gov (United States)

    Thompson, Audrey

    2004-01-01

    Although often viewed as burdensome, academic writing guidelines are rarely treated as actively problematic. Even progressive scholars are unlikely to challenge the cultural assumptions or political investments of academic style guides. Yet standards regarding clarity, precision, appropriateness, sensitivity, and objectivity are not politically…

  10. ADA APA DENGAN KOMUNIKASI ORANG TUA-REMAJA?: PENGARUHNYA TERHADAP AGRESIVITAS REMAJA PADA SESAMA

    Directory of Open Access Journals (Sweden)

    Diana Berlianti

    2017-02-01

    Full Text Available There is a vague link between parent–adolescent communication and adolescents’ aggressiveness. Usually, the agressive perpetrators are the victims from their past experiences of abusive behavior from their surroundings. This present study aimed to examine influence among parent-adolescent communication pattern, parental physically and verbally harsh communication toward adolescents, parents-adolescents mutual avoidance, frequency of adolescents aggressivity toward others, and adolescents aggressiveness. Using Albert Bandura’s learning theoretical framework about violence messages reproduction, this study  have been conducted using 367 adolescents sample of  Bogor District and City. This report used quantitative and using cross sectional study design.  Researcher also employed  self-reported, survey methods in order to collect data. Result shown significant relation and influence among parental physically and verbally communication towards adolescents; parents-adolescents mutual avoidance; frequency of adolescents aggressivity toward others; and adolescents aggressiveness. Using Structural Equation Modelling (SEM analyses, result proved that the victims of violence usually become perpetrators in future life.

  11. Some polite applause for the 2003 APA Division 30 definition of hypnosis.

    Science.gov (United States)

    Woody, Erik; Sadler, Pamela

    The authors argue that the new definition of hypnosis by Division 30 of the American Psychological Association contains questionable information about the role of imagination in hypnosis, about the use versus omission of the word hypnosis in inductions, and about the nature of individual differences and their relation to the standardized scales. In addition, the definition appears to conflate formal and exemplar-based types of definition, and it does not seem particularly well-tuned to the interests of lay persons. The authors advance some suggestions for future definitional efforts.

  12. Transport Research APAS (actions de preparation, d'accompagnement et du suivi)

    DEFF Research Database (Denmark)

    Leleur, Steen; Pedersen, Karsten S.; Bendtsen, Ulla

    1996-01-01

    The aim of the study, dealing with road investments evaluation, is to deliver a single, coherent approach of the full range of road projects. The study draws together, contrasts and compares evaluation procedures and fuses them into an approach to evaluation which embraces both technical performa...

  13. Konsep Nilai Wajar (Fair Value) dalam Standar Akuntansi Berbasis IFRS di Indonesia Apa dan Bagaimana?

    OpenAIRE

    Heri Sukendar W.

    2012-01-01

    This paper is intended to explain the use of the concept of fair value instead of book value. The accounting world in Indonesia during the last few years have made convergency implementation of new accounting standards oriented to the International Financial Reporting Standards (IFRS) issued by International Accounting Standard Boars (IASB). This new accounting standard that emphasizes the concept of fair value compared with book value concept is outdated. The use of the concept of fair value...

  14. Konsep Nilai Wajar (Fair Value dalam Standar Akuntansi Berbasis IFRS di Indonesia Apa dan Bagaimana?

    Directory of Open Access Journals (Sweden)

    Heri Sukendar W.

    2012-05-01

    Full Text Available This paper is intended to explain the use of the concept of fair value instead of book value. The accounting world in Indonesia during the last few years have made convergency implementation of new accounting standards oriented to the International Financial Reporting Standards (IFRS issued by International Accounting Standard Boars (IASB. This new accounting standard that emphasizes the concept of fair value compared with book value concept is outdated. The use of the concept of fair value of the difference and it turned out to be a trigger konvergency change the paradigm of the book value of a simpler, but less information is less transparent. The implementation of accounting standards konverjensi done gradually raises serious problems, this can be seen from postponed the application of PSAK 50 & PSAK 55 in the banking industry. Knowledge and experience of inadequate is a priority of fair value implementation difficulties.

  15. The Model Does Matter II: Admissions and Training in APA-Accredited Counseling Psychology Programs

    Science.gov (United States)

    Norcross, John C.; Evans, Krystle L.; Ellis, Jeannette L.

    2010-01-01

    This study collected information on the acceptance rates, admission standards, financial assistance, student characteristics, theoretical orientations, and select outcomes of American Psychological Association-accredited counseling psychology programs (99% response rate). Results are presented collectively for all 66 counseling programs as well as…

  16. The Fifth Edition of the APA "Publication Manual": Why Its Statistics Recommendations Are So Controversial.

    Science.gov (United States)

    Fidler, Fiona

    2002-01-01

    Identifies deficiencies in the new edition of the American Psychological Association's "Publication Manual," drawing on interviews with some critics and other parties. These include lack of follow-through with explanations and examples of how to report the statistics now recommended. (SLD)

  17. Implementasi Tanggungjawab Sosial PT Petrokimia Gresik pada Masyarakat Lokal: Apa Kata Mereka?

    Directory of Open Access Journals (Sweden)

    I Made Narsa

    2014-12-01

    Full Text Available This study explores and analyzes in depth the impact of CRS program of PT PG on social, economic, and environment conditions of the surrounding society especially in Kelurahan Karangturi, Gresik. We interviewed informant and were supported by monographic data of the county. We found that the implementation of CSR brings positive and real impact to the social conditions of the society as it improves many aspects of the society that includes health, educations, employment, and institutional strengthening through management of bad nutrient infants, scholarships, and improvement in clean water availability and air condition.

  18. Using the APA Guidelines for Psychotherapy with Lesbian, Gay, and Bisexual Clients in Education and Training.

    Science.gov (United States)

    Browning, Christine

    The American Psychological Association's adoption of the Guidelines for Psychotherapy with Lesbian, Gay, and Bisexual Clients has the potential to change the education and training approaches in psychology graduate programs and internship settings. Current research suggests that many graduate students do not receive adequate information about…

  19. Issues in American psychiatry reflected in remarks of APA presidents, 1844-1994.

    Science.gov (United States)

    Geller, J L

    1994-10-01

    The author reviewed the history of American psychiatry for the first 150 years of the American Psychiatric Association's existence (1844-1994) as reflected in remarks of the association's presidents. Presidential addresses or remarks from alternative sources were located for the 120 presidents who served the association between 1844 and 1994. The presidents' remarks on six topics-psychiatric practice, etiology of mental illness, public mental hospitals, alternatives to state hospitals (deinstitutionalization), biologic treatments, and fiscal issues were sampled and arranged chronologically. American psychiatry's history--its innovations, cyclical repetitions, and self-assessments-can be gleaned from this form of data. The presidents' remarks appear to refute the claim that organized American psychiatry has been negligent in criticizing itself.

  20. Workshops Increase Students' Proficiency at Identifying General and APA-Style Writing Errors

    Science.gov (United States)

    Jorgensen, Terrence D.; Marek, Pam

    2013-01-01

    To determine the effectiveness of 20- to 30-min workshops on recognition of errors in American Psychological Association-style writing, 58 introductory psychology students attended one of the three workshops (on grammar, mechanics, or references) and completed error recognition tests (pretest, initial posttest, and three follow-up tests). As a…

  1. Konvergensi Standar Laporan Keuangan ke Standar Pelaporan Keuangan Internasional, Apa dan Bagaimana

    OpenAIRE

    Heri Sukendar W.

    2009-01-01

    This research aims to explain development of the convergence of financial accounting standards under IFRS outline being implemented in Indonesia. In the early part, background of the convergence from Indonesian GAAP to IFRS is discussed, both economically and politically to the latest developments in the convergence to IFRS at the present. Furthermore, it is also described the basic framework of the IFRS, which is the fundamental preparation of financial report under IFRS. At the end, this re...

  2. Etika Bisnis Tak Berjalan di Indonesia: Ada Apa Dalam Corporate Governance?

    Directory of Open Access Journals (Sweden)

    Niki Lukviarman

    2009-08-01

    Full Text Available Tulisan ini membahas berbagai kendala penerapan konsep CG (Corporate Governance di Indonesia, dari sudut pandang etika bisnis. Bagian pertama meninjau ulang makna/pengertian konsep CG. Bagian kedua membahas perkembangan konsep CG berkaitan dengan pandangan umum mengenai pelaksanaan CG di Indonesia. Berbagai kendala penerapan CG di Indonesia, khususnya yang berkaitan dengan etika bisnis, dibahas pada bagian berikutnya, dan diakhiri dengan bagian penutup.[I]n the great ‘chessboard’ of human society, every single piece has a principle of motion of its own, altogether different from that which the legislature might chuse to impress upon it. If those two principles coincide and act in the same direction, the game of human society will go on easily and harmoniously, and is very likely to be happy and successful. If they are opposite or different, the game will go on miserably, and the society must be at all times in the highest degree of disorder. Adam Smith, The Theory of Moral Sentiments (1759, p. 234

  3. Form and Style: Theses, Reports, Term Papers. Eighth Edition. Up-to-Date Information on Chicago, MLA, and APA Documentation.

    Science.gov (United States)

    Campbell, William Giles; And Others

    The eighth edition of this manual, which incorporates recent changes in bibliographical format made by "The Chicago Manual of Style" and the Modern Language Association of America, provides guidance to writers of research papers and reports in college, graduate school, business, government, and the professions. The review of the…

  4. Unexpected immunoresponse to Gal and APA antigens in diabetic type 1 patients receiving neonatal pig islets after 6 years.

    Science.gov (United States)

    Valdés-González, Rafael A; Dorantes, Luis M; Garibay, G Nayely; Bracho-Blanchet, Eduardo; Dávila-Pérez, Roberto; Terán, Luis; Ormsby, Christopher E; Ayala-Sumuano, Jorge-Tonatiuh; Copeman, Laura; White, David J G

    2007-05-01

    Cotransplantation of porcine islets and Sertoli cells into preimplanted subcutaneous devices improve metabolic control in type 1 diabetic patients, and survive grafted for more than 4 years. We report here, further assessment of the endocrine and porcine nature of the surviving cells and the immune responses elicited toward Gal alpha(1,3)-Gal beta(1,4)-GlcNAc (Gal) antigen in patients who received a second and third transplants. No immunosuppressive drugs were administered. We were able to immunostain insulin- and glucagon-positive cells in all biopsies of patients and Sertoli cell markers in 60.9% of biopsies. Additionally, all biopsies tested, amplified the porcine COII gene. Patients demonstrated an increase in antipig antibodies in response to the first transplant with a decreasing response toward the second and third transplants. In all transplants, the IgG levels promptly returned to basal values after 3-4 months. The long-term survival of porcine cells and the reduced humoral immune response to multiple transplants indicate a form of tolerance. We have not been able to find CD25-positive cells, indicating that it is probably an immune accommodation of the graft.

  5. Exploring the APA Fifth Edition "Publication Manual"'s Impact on the Analytic Preferences of Journal Editorial Board Members.

    Science.gov (United States)

    Capraro, Mary Margaret; Capraro, Robert M.

    2003-01-01

    Studied the reporting preferences of editorial board members of four scholarly journals in education and psychology with regard to analytic practices in the fifth edition of the American Psychological Association "Publication Manual." Responses of 106 board members show the movement toward reform in research reporting practices. (SLD)

  6. El uso de recursos abiertos como apoyo en la implementación de las normas APA

    OpenAIRE

    Merelles Lourido, Mónica

    2017-01-01

    México ha puesto en marcha diferentes iniciativas desarrollando programas enfocados a desarrollar conocimiento, a través de CONACYT, INIC, SIN y la expedición de leyes para coordinar y promover el desarrollo científico y tecnológico, pasos importantes para la adopción de una cultura de la investigación (Canales, 2011). Según Ramírez (2015), las universidades se han preocupado por generar y compartir conocimiento de sus investigado...

  7. PARADOXOS ENTRE TAIPU DE FORA E TAIPU DE DENTRO / APA DE MARAÚ-BAHIA: TURISMO E IDENTIDADE LOCAL

    Directory of Open Access Journals (Sweden)

    Ivan Rêgo Aragão

    2011-02-01

    Full Text Available Normal 0 21 false false false PT-BR X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabela normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} O presente trabalho tem como objeto de estudo duas localidades geograficamente próximas, mas díspares em suas realidades: Taipu de Fora e de Dentro, ambas na Bahia. O objetivo foi o de realizar um estudo comparativo sobre a ocupação do espaço pelo turismo, e seus reflexos na identidade dos dois povoados. Foi realizada uma pesquisa qualitativa exploratória, primeiramente através de pesquisa bibliográfica, seguida de observação in loco e entrevistas abertas e semiestruturadas. Ainda em campo, e após a visita, buscou-se relacionar os conceitos de ‘alma do lugar’, memória, sentimento de pertença e patrimônio imaterial. A análise dos resultados foi realizada relacionando-se os relatos coletados na pesquisa exploratória, com a observação direta, buscando-se as aproximações e as diferenças na relação entre turismo, espaço e identidade. Dessa forma, a relevância deste estudo se dá ao estimular a reflexão acerca das contradições proporcionadas pela atividade turística.  

  8. THE HABITAT CHARACTERIZATION OF Cardisoma guanhumi LATREILLE, 1828 (DECAPODA, GECARCINIDAE THE APA COAST OF CORAL (PERNAMBUCO AND ALAGOAS, BRAZIL

    Directory of Open Access Journals (Sweden)

    Maria do Carmo Ferrão SANTOS

    2016-09-01

    Full Text Available In the period from July to September 2012, a survey was made of the number of burrows of blue land crab (Cardisoma guanhumi, both in twelve profiles distributed in areas of mangrove, positioned perpendicularly to the wetlands of the Una's River (Pernambuco and Camaragibe's River (Alagoas, aiming to acquire information on the distribution of holes in different types of topographies. The depth of burrows and the salinity and temperature of the water at the bottom of the burrows was registered. In Pernambuco and Alagoas, the profiles covered steep areas (with a gradient of 4.5° and shallow areas (with a gradient of 0.02°. The maximum distance between existing burrows in the profiles, ranged from 58m and 359.5m, compared to a benchmark level (RN. The burrows depths ranged from 0.45m to 1.90m, with an depth average of 0.99m (DP = 0,29. The maximum depth of the burrows can be justified by the fact that there is less availability of water in northeastern soils.It is recommended, studied the mangroves, the establishment of an exclusion zone to preserve the habitat of Cardisoma guanhumi, a distance of at least 200m above the high tide mark. Keywords: blue land crab; mangrove; burrows.

  9. Training and education in religion/spirituality within APA-accredited clinical psychology programs: 8 years later.

    Science.gov (United States)

    Schafer, Rachel M; Handal, Paul J; Brawer, Peter A; Ubinger, Megan

    2011-06-01

    This study was a follow up investigation of Brawer et al.'s (Prof Psychol Res Pr 33(2):203-206, 2002) survey of education and training of clinical psychologists in religion/spirituality. Directors of clinical training were surveyed to determine whether changes had occurred in the coverage of religion and spirituality through course work, research, supervision, and in the systematic coverage of the content area. Results indicated an increased coverage in the areas of supervision, dedicated courses, inclusion as part of another course, and research. There was no increase in systematic coverage, but significantly more programs provided at least some coverage. The current study also assesses other areas of incorporation as well as directors' opinions regarding the importance of religion/spirituality in the field of psychology.

  10. What Is Psychiatry?

    Medline Plus

    Full Text Available ... Rule Advocacy & APAPAC APA Sites APA Publishing APA Learning Center APA Foundation APA Annual Meeting Psychiatric ... Competency Awards & Leadership Opportunities Advocacy & APAPAC ...

  11. Detection of antipolymer antibodies (APA) in serum of women with silicone breast implants. Introduction and performance of the assay in the RIVM

    NARCIS (Netherlands)

    de Jong WH; Spiekstra SW; van Loveren H; LPI

    1998-01-01

    Siliconen bevattende borst implantaten (SBI) worden veelvuldig gebruikt om medische en kosmetische redenen. De laatste tijd is een discussie op gang gekomen dat het aanwezig zijn van een siliconen borstimplantaat mogelijk kan leiden tot gezondheidsklachten. Recentelijk is een laboratoriumtest

  12. Society for Health Psychology (APA Division 38) and Society of Behavioral Medicine joint position statement on the Medicare Diabetes Prevention Program.

    Science.gov (United States)

    Fitzpatrick, Stephanie L; Wilson, Dawn K; Pagoto, Sherry L

    2017-06-01

    Beginning in January 2018, the Centers for Medicare and Medicaid Services (CMS) plans to cover the Diabetes Prevention Program (DPP), also referred to as Medicare DPP. The American Psychological Association Society for Health Psychology (SfHP) and the Society for Behavioral Medicine (SBM) reviewed the proposed plan. SfHP and SBM are in support of the CMS decision to cover DPP for Medicare beneficiaries but have a significant concern that aspects of the proposal will limit the public health impact. Concerns include the emphasis on weight outcomes to determine continued coverage and the lack of details regarding requirements for coaches. SfHP and SBM are in strong support of modifications to the proposal that would remove the minimum weight loss stipulation to determine coverage and to specify type and qualifications of "coaches."

  13. APA: U free Pu pin in a heterogeneous assembly to improve Pu loading in a PWR - neutronic, thermo-hydraulic and manufacturing studies

    International Nuclear Information System (INIS)

    Porta, J.; Puill, A.; Bauer, M.; Matheron, P.

    1999-01-01

    After having presented the specific context of France with respect to the fuel cycle and reprocessing, the problem of plutonium fuel utilization is posed. If one of the solutions, a pressurized water reactor (PWR) with an increased moderation ratio seems possible, it entails making excessive changes to the reactor, the control systems, and the general architecture of the steam supply system. Another solution consists in modifying the fuel itself so as to eliminate conversion on 238 U by using plutonium (Pu) in a neutronically inert matrix. However, the disadvantage of this type of fuel is that it has very low Doppler and draining coefficients and a very small delayed neutron fraction. To enable using these fuels, a heterogeneous assembly has to be defined, in which standard UO 2 rods provide the physical properties required to ensure acceptable safety coefficients. (author)

  14. Detection of VDR gene ApaI and TaqI polymorphisms in patients with type 2 diabetes mellitus using PCR-RFLP method in a Turkish population

    NARCIS (Netherlands)

    Dilmec, Fuat; Uzer, Elmas; Akkafa, Feridun; Kose, Elif; van Kuilenburg, André B. P.

    2010-01-01

    Type 2 diabetes mellitus (T2DM) is by far the most common type of diabetes and is characterized by insulin resistance and altered insulin secretion. Some genes, such as the vitamin D receptor gene (VDR, NM_001017535; GI: 7421), involved in its metabolic pathway have been regarded as good candidates

  15. Journal article reporting standards for qualitative primary, qualitative meta-analytic, and mixed methods research in psychology: The APA Publications and Communications Board task force report

    OpenAIRE

    Levitt, H. M.; Bamberg, M.; Creswell, J. W.; Frost, D. M.; Josselson, R.; Suárez-Orozco, C.

    2018-01-01

    The American Psychological Association Publications and Communications Board Working Group on Journal Article Reporting Standards for Qualitative Research (JARS–Qual Working Group) was charged with examining the state of journal article reporting standards as they applied to qualitative research and with generating recommendations for standards that would be appropriate for a wide range of methods within the discipline of psychology. These standards describe what should be included in a resea...

  16. Búsqueda de bibliografía científica en línea : Armado de referencias con normas APA

    OpenAIRE

    Gómez, María Florencia

    2016-01-01

    En el trabajo académico y profesional del psicólogo, es central la presentación de propuestas de trabajo y de investigación. Por ello, un paso necesario es saber buscar y organizar la bibliografía académica para armar su fundamentación. Esta ficha tiene el propósito de introducir algunas claves para orientar la búsqueda bibliográfica y recuperar contenido académico evaluado por pares, de relevancia en el campo de trabajo del psicólogo. Asimismo, se realiza una síntesis de las formas de citado...

  17. -H.sub.2./sub.-lengthening of the internucleotide linkage in the ApA dimer can improve its conformational compatibility with its natural polynucleotide counterpart

    Czech Academy of Sciences Publication Activity Database

    Hanuš, J.; Barvík, I.; Ruszová-Chmelová, K.; Štěpánek, J.; Turpin, P. Y.; Bok, J.; Rosenberg, Ivan; Endová, Magdalena

    2001-01-01

    Roč. 29, č. 24 (2001), s. 5182-5194 ISSN 0305-1048 R&D Projects: GA AV ČR IAA4055902; GA ČR GA203/01/1166; GA MŠk VS97113 Institutional research plan: CEZ:AV0Z4055905 Keywords : phosphonate internucleotide linkage Subject RIV: CC - Organic Chemistry Impact factor: 6.373, year: 2001

  18. Apa l’Etrusco sbarca a Roma e passa il testimone ad Ati. Un cortometraggio tridimensionale per raccontare il santuario di Portonaccio a Veio

    Directory of Open Access Journals (Sweden)

    Alfonsina Russo

    2015-08-01

    Full Text Available Computer graphics movies are a favourite media for edutainment. The 3D stereoscopic short movie “Ati at the discovery of Veii” is an interesting example of philologically accurate reconstructions coupled with a communication aimed at a wide audience.  Developed by Cineca for a joint project involving the National Etruscan Museum of Villa Giulia and Genus Bononiae – Museum of the History of Bologna, the movie is grounded on the software Blender and a strong open source commitment.

  19. El enfoque sistémico: aplicación al subsector de agua potable y alcantarillado (A.P.A.

    Directory of Open Access Journals (Sweden)

    Jorge E. Triviño M.

    1987-09-01

    Full Text Available Al presentar en este documento una síntesis de los principios básicos del análisis de sistemas y su aplicación al sector de agua potable y saneamiento, se desea contribuir en forma práctica a la divulgación y aplicación de una ciencia relativamente joven que permite mejorar cada vez más las organizaciones y su administración, sin causar traumatismos ni ocasionar resistencias al cambio deseado, en beneficio de la salud del hombre.

  20. What Is Psychiatry?

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  1. What Is Psychiatry?

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    Full Text Available ... Families Become an APA Member Learn More Explore APA Psychiatrists Residents & Medical Students Patients & Families About APA ... Psychiatric News Message from President APA Blogs Join APA General Members Residents and Fellows Medical Students International ...

  2. Anxiety Disorders

    Science.gov (United States)

    ... in your area today. Search Now APA Resources APA Resources for Patients and Families Warning Signs of ... 2017 Become an APA Member Learn More Explore APA Psychiatrists Residents & Medical Students Patients & Families About APA ...

  3. Choosing a Career in Psychiatry

    Science.gov (United States)

    ... 22 Become an APA Member Learn More Explore APA Psychiatrists Residents & Medical Students Patients & Families About APA ... Psychiatric News Message from President APA Blogs Join APA General Members Residents and Fellows Medical Students International ...

  4. What Is Psychiatry?

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    Full Text Available ... Advocacy & APAPAC APA Sites APA Publishing APA Learning Center APA Foundation APA Annual Meeting Psychiatric News PsychiatryOnline ... or troubling symptoms so the patient can function better. Depending on the extent of the problem, treatment ...

  5. What Is Psychiatry?

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    Full Text Available ... Rule Advocacy & APAPAC APA Sites APA Publishing APA Learning Center APA Foundation APA Annual Meeting Psychiatric News ... training then spends at least three additional years learning the diagnosis and treatment of mental health, including ...

  6. Diversidade e uso de recursos medicinais do carrasco na APA da Serra da Ibiapaba, Piauí, Nordeste do Brasil Diversity and use of medicinal resources of "carrasco" in the EPA of Serra da Ibiapaba, Piauí, Northeast Brazil

    Directory of Open Access Journals (Sweden)

    E.M.F. Chaves

    2012-01-01

    Full Text Available O presente estudo foi realizado na Área de Proteção Ambiental da Serra da Ibiapaba no município de Cocal, Piauí. Objetivou-se realizar o levantamento das plantas utilizadas pela comunidade, das partes usadas, das indicações, das formas de uso e de administração dessas plantas. Foram realizadas 80 entrevistas com 100% dos moradores de notório saber, residentes no município que utilizavam e/ou comercializavam plantas de uso medicinal. Para definição da amostra utilizou-se o método de bola de neve. Em incursões guiadas por membros da comunidade, foram coletadas as etnoespécies citadas. Após essa etapa, as espécies foram identificadas em laboratório e calculado o Fator de Consenso dos Informantes (FCI para cada categoria de doença. O material foi incorporado ao acervo do Herbário Graziela Barroso (TEPB/UFPI. Foram identificadas 76 espécies, distribuídas em 61 gêneros e 36 famílias. Sobresairam-se Leguminosae com 22 espécies (28,9%, seguida por Euphorbiaceae com 6 (7,8%, e Solanaceae 4 (5,2%. Os gêneros Croton L. e Hymenaea L. obtiveram o maior destaque, somando 8 (10,5% do total de espécies. As espécies mais presentes nas indicações de uso foram Ximenia americana com 14 (5,9%, Tabebuia impetiginosa com 9 (3,9% e Anacardium occidentale com 7 (2,9%. Observou-se que 80,5% dos entrevistados tinham mais de 50 anos e residiam no município a mais de 20 anos, sendo que 70% possuíam apenas ensino fundamental incompleto e 20 % eram analfabetos. Houve maior consenso entre os informantes para tratamento das doenças do sistema respiratório (0,66 e do aparelho digestório (0,65. A maioria das indicações de usos 81 (34,17% relatados para 28 (36,8% das espécies visavam curar males do sistema respiratório, tais como asma, bronquite, gripe, inflamação na garganta, pneumonia e sinusite. Para o preparo dos remédios, as partes mais utilizadas foram as cascas (30,5%, as folhas (29,4% e as raízes (12,6%. As preparações mais comuns foram os chás, garrafadas e lambedores, administrados por via oral. Os resultados sinalizaram para a importância do potencial bioativo da vegetação do carrasco.The present study was carried out in the Environmental Protection Area of Serra da Ibiapaba, in Cocal Municipality, Piauí. The study aimed to perform a survey of the plants used by the community, including used parts, recommended use, forms of use and administration of these plants. A total of 80 interviews were done with 100% of denizens with noteworthy knowledge who lived in that municipality and used and/or commercialized plants of medicinal use. To define the sample the snowball method was adopted. In tours guided by members of the community, the cited ethnospecies were collected. After this stage, the species were identified in the laboratory and the Informant Consensus Factor (ICF was calculated for each disease category. The material was incorporated in the collection of Herbarium Graziela Barroso (TEPB/UFPI. A total of 76 species were identified, distributed into 61 genera and 36 families. Leguminosae was the major family with 22 species (28.9%, followed by Euphorbiaceae with 6 (7.8% and Solanaceae with 4 (5.2%. Croton L. and Hymenaea L. were the most important genera, comprising 8 (10.5% of the total species. The species most commonly recommended for medicinal use were Ximenia americana with 14 (5.9%, Tabebuia impetiginosa with 9 (3.9% and Anacardium occidentale with 7 (2.9%. The age of 80.5% of the interviewees was over 50 years and they had been living in the municipality for more than 20 years, while 70% had only incomplete elementary education and 20% were illiterate. There was greater consensus among the informants for treatment of respiratory diseases (0.66 and problems of the digestive system (0.65. The most common recommendation of use, 81 (34.17%, reported for 28 (36.8% of the species, aimed to cure problems of the respiratory system, such as asthma, bronchitis, influenza, inflammation of the throat, pneumonia, and sinusitis. In the preparation of medicines, the parts most commonly used were the bark (30.5%, the leaves (29.4% and the roots (12.6%. The most common preparations were tea, balm and lickers, administered orally. The results indicated the importance of the bioactive potential of "carrasco" vegetation.

  7. El artículo científico para revista académica: Pautas para su planificación y edición de acuerdo con el modelo APA

    Directory of Open Access Journals (Sweden)

    María Elena Camacho Villalobos

    2014-01-01

    Full Text Available A partir de la experiencia de las autoras como directoras y editoras de revistas académicas, en comités editoriales, en arbitrajes de textos, en cursos impartidos para la redacción de artículos y sobre la escritura en general, y en la revisión filológica, se propone este artículo. En estas experie ncias han detectado diversas dificultades en la escritura de artículos, por lo cual plantean los indicadores de calidad e información pertinente para la escogencia del medio en que se quiere publicar; formato general, modalidades y partes constituyentes de l artículo; la construcción de la cohesión y la coherencia; la planificación del texto y la elaboración de las paráfrasis. Bosquejan elementos que se deben revisar antes de enviar el artículo, así como estrategias para gestionar la publicación en la revist a. Con ello, atienden detalles que tienen que ver con un asunto pragmático y formal. La síntesis y el análisis constituyen herramientas para la elaboración de la paráfrasis, por tanto, su abordaje se ha considerado relevante debido a que facilitan el acopi o de información de diversas fuentes y su adecuado empleo en el documento propio. Recalcan la noción de que escribir es un acto comunicativo en el cual se debe colaborar con los potenciales lectores o lectoras con un texto cohesionado, coherente, conciso y claro. Este constituye una propuesta de lingüística aplicada a la construcción del texto académico, de provecho para diversas disciplinas.

  8. Survey of vegetation and its diametric distribution in an area of cerrado sensu stricto and riparian forest fragment at Dois Irmãos stream in the Area of Environmental Protection (APA of Cafuringa, Federal District, Brazil.

    Directory of Open Access Journals (Sweden)

    José Elias de Paula

    2009-09-01

    Full Text Available All individual trees with a diameter at breast height (DBH of over 5cm, as well as the natural succession, were identified in 2,500m2 of the savannah (cerrado sensu stricto area and in 5,000m2 of the “Dois Irmãos” riparian forest vegetation (15º30’19”S and 48º06’18”W. The floristic composition of the cerrado sensu stricto was composed by 100 trees distributed in 25 species, and the riparian forest consisted of 155 trees distributed in 55 species. The natural regeneration was formed with 211 and 287 individuals in the cerrado sensu stricto and riparian forest distributed into 38 and 55 species respectively. The basal areas of the trees occupied 3.40m2.ha-1 in the cerrado sensu stricto and 5.08m2.ha-1 in the riparian forest. The diametric distribution curves for both plant communities, adjusted by the Meyers equation, demonstrated a typical tendency of reversed-J shape with strongly antropic action in the 11 to 17cm diametric classes.

  9. From the American Psychological Association to the American Psychology Association--An Organization for Psychologists or for the Discipline? 2007 Annual Report of the APA Policy and Planning Board

    Science.gov (United States)

    American Psychologist, 2008

    2008-01-01

    Each year, the American Psychological Association's Policy and Planning Board takes the pulse of the Association and the discipline as a whole and writes a report that represents the Board's best appraisal of a fundamental policy. Our main objective, however, is not simply to assess the current situation but to look forward on behalf of the…

  10. Structure and dynamics of the ApA, ApC, CpA and CpC RNA dinucleoside monophosphates resolved with NMR scalar spin-spin couplings

    Czech Academy of Sciences Publication Activity Database

    Vokáčová, Zuzana; Buděšínský, Miloš; Rosenberg, Ivan; Schneider, Bohdan; Šponer, Jiří; Sychrovský, Vladimír

    2009-01-01

    Roč. 113, č. 4 (2009), s. 1182-1191 ISSN 1520-6106 R&D Projects: GA AV ČR IAA400550701 Institutional research plan: CEZ:AV0Z40550506; CEZ:AV0Z50040507; CEZ:AV0Z50520701 Keywords : RNA * NMR * MD Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 3.471, year: 2009

  11. The conformational compatibility of the ApA dimer with poly(rU) improved by the -CH.sub.2./sub.- lengthening of the dimer internucleotide of the dimer internucleotide linkage - A 2D raman isothermal study

    Czech Academy of Sciences Publication Activity Database

    Hanuš, J.; Barvík, I.; Štěpánek, J.; Turpin, P. Y.; Bok, J.; Rosenberg, Ivan; Petrová, Magdalena

    2002-01-01

    Roč. 9, č. 1 (2002), s. 37-38 ISSN 1211-5894. [Meeting of the Czech and Slovak Structural Biologists /2./. 13.03.2003-15.03.2003, Nové Hrady] R&D Projects: GA ČR GA203/01/1166; GA AV ČR IAA4055902 Institutional research plan: CEZ:AV0Z4055905 Keywords : 2D Raman data Subject RIV: CE - Biochemistry

  12. Structure and dynamics of the ApA, ApC, CpA and CpC RNA dinucleoside monophosphates resolved with NMR scalar spin-spin couplings

    Czech Academy of Sciences Publication Activity Database

    Vokáčová, Zuzana; Schneider, Bohdan; Buděšínský, Miloš; Rosenberg, Ivan; Šponer, Jiří; Sychrovský, Vladimír

    2009-01-01

    Roč. 16, 1a (2009), b52-b52 ISSN 1211-5894. [Meeting of the Czechoslovak and Slovak Biologists /7./. 12.03.2009-14.03.2009, Nové Hrady] R&D Projects: GA AV ČR IAA400550701 Institutional research plan: CEZ:AV0Z40550506; CEZ:AV0Z50040507 Keywords : NMR * dinucleoside monophosphate Subject RIV: CF - Physical ; Theoretical Chemistry

  13. Revisión acerca de las normas para la presentación de referencias bibliográficas según el estilo de la American Psychological Association (APA)

    OpenAIRE

    Cristian Carlos Abalos

    2003-01-01

    Numerosas instituciones han hecho accesibles sus datos a través de la infraestructura de comunicaciones que ofrece la internet, a través de la World Wide Web. Su amplia versatilidad permite trabajar con ficheros de texto, sonido, imágenes fijas y/o en movimiento, así como la capacidad de acceder desde ella a todos los otros servicios de internet. Bajo este esquema tecnológico surgieron los distintos recursos electrónicos de información. Para la preparación de un inform...

  14. The American Academy of Clinical Neuropsychology, National Academy of Neuropsychology, and Society for Clinical Neuropsychology (APA Division 40) 2015 TCN Professional Practice and 'Salary Survey': Professional Practices, Beliefs, and Incomes of U.S. Neuropsychologists.

    Science.gov (United States)

    Sweet, Jerry J; Benson, Laura M; Nelson, Nathaniel W; Moberg, Paul J

    2015-01-01

    The current survey updated professional practice and income information pertaining to clinical neuropsychology. Doctoral-level members of the American Academy of Clinical Neuropsychology, Division 40 (Clinical Neuropsychology) of the American Psychological Association, and the National Academy of Neuropsychology and other neuropsychologists, as well as postdoctoral trainees in the Association of Postdoctoral Programs in Clinical Neuropsychology and at other training sites were invited to participate in a web-based survey in early 2015. The sample of 1777 respondents, of whom 1579 were doctoral-level practitioners and 198 were postdoctoral trainees, was larger than the prior 2010 income and practice survey. The substantial proportional change in gender has continued, with women now a clear majority in the postdoctoral trainee sample as well as in the practitioner sample. Dissimilar from the median age trajectory of American Psychological Association members, the median age of clinical neuropsychologists remains essentially unchanged since 1989, indicating a substantial annual influx of young neuropsychologists. The question of whether the Houston Conference training model has become an important influence in the specialty can now be considered settled in the affirmative among postdoctoral trainees and practitioners. Testing assistant usage remains commonplace, and continues to be more common in institutions. The vast majority of clinical neuropsychologists work full-time and very few are unemployed and seeking employment. The numbers of neuropsychologists planning to retire in the coming 5-10 years do not suggest a "baby boomer" effect or an unexpected bolus of planned retirements in the next 10 years that would be large enough to be worrisome. Average length of time reported for evaluations appears to be increasing across time. The most common factors affecting evaluation length were identified, with the top three being: (1) goal of evaluation, (2) stamina/health of examinee, and (3) age of examinee. Pediatric specialists remain more likely than others to work part-time, more likely to work in institutions, report lower incomes than respondents with a lifespan professional identity, and are far more likely to be women. Incomes continue to vary considerably by years of clinical practice, work setting, amount of forensic practice, state, and region of country. Neurologists are the number one referral source in institutions and in private practice, as well as for pediatric, adult, and lifespan practitioners. Learning disability is no longer among the top five conditions seen by pediatric neuropsychologists; traumatic brain injury and seizure disorder are common reasons for clinical evaluations at all age ranges. There is a continued increase in forensic practice and a clear consensus on the use of validity testing. There is a substantial interest in subspecialization board certification, with the greatest interest evident among postdoctoral trainees. Income satisfaction, job satisfaction, and work-life balance satisfaction are higher for men. Job satisfaction varies across general work setting and across age range of practice. Work-life balance satisfaction is moderately correlated with income satisfaction and job satisfaction. Again in this five-year interval survey, a substantial majority of respondents reported increased incomes, despite experiencing substantial negative practice effects related to changes in the US health care system. Numerous breakdowns related to income and professional activities are provided. Professional practice survey information continues to provide valuable perspectives regarding consistency and change in the activities, beliefs, and incomes of US clinical neuropsychologists.

  15. What Is Psychiatry?

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    Full Text Available ... Sign In Join General Residents and Fellows Medical Students International close menu Psychiatrists Education Practice Cultural Competency Awards & ... Join APA General Members Residents and Fellows Medical Students International Become a Fellow APA Sites APA Publishing APA ...

  16. What Is Psychiatry?

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    Full Text Available ... the President Reporting on Mental Health Conditions APA Blogs Annual Meeting Goldwater Rule Advocacy & APAPAC APA Sites ... News Releases Psychiatric News Message from President APA Blogs Join APA General Members Residents and Fellows Medical ...

  17. What Is Psychiatry?

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    Full Text Available About APA APA's Vision, Mission, Values, and Goals Meet Our Organization Read APA Organization Documents and Policies Work at APA Contact Us Newsroom News Releases Message from the President Reporting on ...

  18. What Is Psychiatry?

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    Full Text Available ... Mental Health Conditions APA Blogs Annual Meeting Goldwater Rule Advocacy & APAPAC APA Sites APA Publishing APA Learning ... psychological testing and evaluation. More Resources World Psychiatric Association American Association of Child and Adolescent Psychiatry American ...

  19. What Is Psychiatry?

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    Full Text Available About APA APA's Vision, Mission, Values, and Goals Meet Our Organization Read APA Organization Documents and Policies Work at APA Contact Us Newsroom News Releases Message from ...

  20. What Is Psychiatry?

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    Full Text Available ... Health Conditions APA Blogs Annual Meeting Goldwater Rule Advocacy & APAPAC APA Sites APA Publishing APA Learning Center ... Psychiatrists Education Practice Cultural Competency Awards & Leadership Opportunities Advocacy & APAPAC Meetings Search Directories/Databases International Registry Residents & ...

  1. What Is Psychiatry?

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    Full Text Available About APA APA's Vision, Mission, Values, and Goals Meet Our Organization Read APA Organization Documents and Policies Work at APA Contact Us Newsroom News Releases Message from the President Reporting on Mental Health Conditions APA Blogs Annual Meeting Goldwater ...

  2. 75 FR 5888 - Federal Manufactured Home Construction and Safety Standards and Other Orders: HUD Statements That...

    Science.gov (United States)

    2010-02-05

    ....C. 551 et seq.) (the APA) definition of a ``rule.'' The APA definition states, in pertinent part... the APA, courts have developed extensive case law interpreting the APA's definition of a rule. (See, e... demonstrating Congress's intent to incorporate the APA's definition of a rule as developed by the courts, except...

  3. 77 FR 123 - Final Reissuance of General NPDES Permits (GP) for Facilities Related to Oil and Gas Extraction

    Science.gov (United States)

    2012-01-03

    ... Administrative Procedure Act (APA), or any other law, to publish general notice of proposed rulemaking.'' The RFA... NPDES general permits are permits, not rulemakings, under the APA and thus not subject to APA rulemaking...

  4. 78 FR 20316 - Final Issuance of General NPDES Permits (GP) for Small Suction Dredges in Idaho

    Science.gov (United States)

    2013-04-04

    ... Procedure Act (APA), or any other law, to publish general notice of proposed rulemaking.'' The RFA exempts... permits are permits, not rulemakings, under the APA and thus not subject to APA rulemaking requirements or...

  5. 78 FR 34910 - Approval and Promulgation of Implementation Plans; Maryland; Revisions to the State...

    Science.gov (United States)

    2013-06-11

    ... Procedure Act (APA), which authorizes agencies to dispense with public participation and which allows an... otherwise provided for in the APA). DATES: This action is effective June 11, 2013. ADDRESSES: EPA has... Administrative Procedure Act (APA) [[Page 34911

  6. The Army Preposition Afloat Program: Is It a Program We Need?

    National Research Council Canada - National Science Library

    Curl, William

    1998-01-01

    ... of most required classes. This paper addresses the evolution of the APA program, describes the current and planned APA program, discusses management of the APA, and looks critically at the value of the program in support...

  7. 78 FR 17661 - Proposed Reissuance of a General NPDES Permit for Oil and Gas Exploration Facilities in the...

    Science.gov (United States)

    2013-03-22

    ... Administrative Procedure Act (APA), or any other law, to publish general notice of proposed rulemaking.'' The RFA... NPDES general permits are permits, not rulemakings, under the APA and thus not subject to APA rulemaking...

  8. What Is Psychiatry?

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  9. 75 FR 65483 - Proposed Reissuance of General NPDES Permits (GP) for Alaskan Medium-Size Suction Dredging...

    Science.gov (United States)

    2010-10-25

    ... proposed rule'' for which the agency ``is required by section 553 of the Administrative Procedure Act (APA... permits are permits, not rulemakings, under the APA and thus not subject to APA rulemaking requirements or...

  10. 75 FR 3731 - Proposed Issuance of a General NPDES Permit for Small Suction Dredging-Permit Number IDG-37-0000

    Science.gov (United States)

    2010-01-22

    ... Procedure Act (APA), or any other law, to publish general notice of proposed rulemaking.'' The RFA exempts... permits are permits, not rulemakings, under the APA and thus not subject to APA rulemaking requirements or...

  11. 76 FR 45792 - Proposed Reissuance of a General NPDES Permit for Facilities Related to Oil and Gas Extraction

    Science.gov (United States)

    2011-08-01

    ... proposed rule'' for which the agency ``is required by section 553 of the Administrative Procedure Act (APA... permits, not rulemakings, under the APA and thus not subject to APA rulemaking requirements or the RFA...

  12. What Is Psychiatry?

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    Full Text Available ... APA's Vision, Mission, Values, and Goals Meet Our Organization Read APA Organization Documents and Policies Work at APA Contact Us ... choose additional training in psychoanalysis or in psychiatric research. Where Do Psychiatrists Work? Psychiatrists work in a ...

  13. What Is Psychiatry?

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    Full Text Available ... and Policies Work at APA Contact Us Newsroom News Releases Message from the President Reporting on Mental ... Learning Center APA Foundation APA Annual Meeting Psychiatric News PsychiatryOnline Workplace Mental Health Sign In Join General ...

  14. 24 CFR 3280.304 - Materials.

    Science.gov (United States)

    2010-04-01

    ... APA Trademarks)—PS 1-95. APA Design/Construction Guide, Residential and Commercial—APA E30-P-1996...-Plywood Beams—APA H-815E (PDS Supplement #5), 1995. Panel Design Specification—APA D410A, 2004. Design and Fabrication of Glued Plywood-Lumber Beams—APA-S 812Q, Suppl. 2-1992. Design and Fabrication of Plywood Curved...

  15. Status Report on Speech Research. A Report on the Status and Progress of Studies on the Nature of Speech, Instrumentation for Its Investigation, and Practical Applications.

    Science.gov (United States)

    1985-01-01

    47 .41 apa apa apa a-pa apa wpa apa wpa CH .96 .87 .95 .97 -.02 .35 .22 .26 NM .93 .94 .91 .92 .49 .22 .61 -.02 JE .92 .94 .97 .89 .39 .29 .36 .64 BT...A * EA 15 A oma0 *normal ustressed norma unstressed "fast stressed o:5K.’. L. . .. S :SK." . 50 100 150 200 DURATION (ins) 25 CLOSING GESTIURES (n

  16. What Is Psychiatry?

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  17. 77 FR 21099 - Public Water System Supervision Program Approval for the State of Ohio

    Science.gov (United States)

    2012-04-09

    ... the National Primary Drinking Water Regulations, including the Administrative Penalty Authority (APA... the APA since October 1, 1999, with amendments effective on October 17, 2003. Ohio EPA's revised...

  18. What Is Psychiatry?

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    Full Text Available ... Values, and Goals Meet Our Organization Read APA Organization Documents and Policies Work at APA Contact Us ... Competency Awards & Leadership Opportunities Advocacy & APAPAC ...

  19. Determination of cephalosporin acylase activity by biological and ...

    African Journals Online (AJOL)

    PRECIOUS

    2009-12-01

    Dec 1, 2009 ... microorganisms with cephalosporin acylase activity was developed. The core part of cephalosporin was replaced by 6-amino penicillinic acid (6-APA) to generate new substrates glutaryl-6-APA and adipoyl-6-APA for screen- ing. Serratia marcescens that is sensitive to 6-APA and resistant to penicillin G, ...

  20. 78 FR 60226 - Amendments To Implement Certain Provisions of the Moving Ahead for Progress in the 21st Century...

    Science.gov (United States)

    2013-10-01

    ... available to Federal agencies under the Administrative Procedure Act (APA). DATES: Effective Date: This... public comment under procedures required by the APA, as provided in 5 U.S.C. 553(b) and (c). The APA, in... receiving public comment, in accordance with the APA. For these same reasons, the rule will be effective on...

  1. 77 FR 55695 - Approval and Promulgation of Implementation Plans; Virginia; Revisions to the State...

    Science.gov (United States)

    2012-09-11

    ... Administrative Procedure Act (APA). This exemption in the APA authorizes agencies to dispense with public... otherwise provided for in the APA. DATES: This action is effective September 11, 2012. ADDRESSES: EPA has...'' exemption in section 553(b)(3)(B) of the Administrative Procedure Act (APA). This exemption authorizes...

  2. 75 FR 69889 - Extension of Deadline for Action on the Second Section 126 Petition From New Jersey

    Science.gov (United States)

    2010-11-16

    ... Act (APA) C. Effective Date Under the APA III. Statutory and Executive Order Reviews A. Executive... Administrative Procedures Act (APA) This document is a final agency action, but may not be subject to the notice-and-comment requirements of the APA, 5 U.S.C. 553(b). The EPA believes that, because of the limited...

  3. 75 FR 37730 - National Emission Standards for Hazardous Air Pollutants From Petroleum Refineries

    Science.gov (United States)

    2010-06-30

    ... reference. Section 553 of the Administrative Procedure Act (APA), 5 U.S.C. 553(b)(B), provides that, when an... 553(b)(B) of the APA, the procedures in section 307(d) in subsection 553(b) of the APA, the procedures... subject to notice and comment requirements under the APA or any other statute (see Section I of this...

  4. 42 CFR 137.309 - How are NEPA and NHPA obligations typically enforced?

    Science.gov (United States)

    2010-10-01

    ... may only be filed in Federal court under the provisions of the APA, 5 U.S.C. 701-706. Under the APA, a... the court's views for those of the agency. Jury trials and civil discovery are not permitted in APA... injunctive relief to the interested party. No money damages or fines are permitted in APA proceedings. ...

  5. 75 FR 39633 - Extension of Deadline for Action on Section 126 Petition From New Jersey

    Science.gov (United States)

    2010-07-12

    ... Procedures Act (APA) C. Effective Date Under the APA III. Statutory and Executive Order Reviews A. Executive... Procedures Act (APA) This document is a final agency action, but may not be subject to the notice-and-comment requirements of the APA, 5 U.S.C. 553(b). The EPA believes that, because of the limited time provided to make a...

  6. The Incidence and Anatomy of Accessory Pudendal Arteries as Depicted on Multidetector-Row CT Angiography: Clinical Implications of Preoperative Evaluation for Laparoscopic and Robot-Assisted Radical Prostatectomy

    International Nuclear Information System (INIS)

    Park, Beom Jin; Sung, Deuk Jae; Kim, Min Ju; Cho, Sung Bum; Kim, Yun Hwan; Chung, Kyoo Byung; Kang, Seok Ho; Cheon, Jun

    2009-01-01

    To help preserve accessory pudendal arteries (APAs) and to ensure optimal postoperative sexual function after a laparoscopic or robot-assisted radical prostatectomy, we have evaluated the incidence of APAs as detected on multidetector-row CT (MDCT) angiography and have provided a detailed anatomical description. The distribution of APAs was evaluated in 121 consecutive male patients between February 2006 and July 2007 who underwent 64- channel MDCT angiography of the lower extremities. We defined an APA as any artery located within the periprostatic region running parallel to the dorsal vascular complex. We also subclassified APAs into lateral and apical APAs. Two radiologists retrospectively evaluated the origin, course and number of APAs; the final APA subclassification based on MDCT angiography source data was determined by consensus. We identified 44 APAs in 36 of 121 patients (30%). Two distinct varieties of APAs were identified. Thirty-three APAs (75%) coursed near the anterolateral region of the prostatic apex, termed apical APAs. The remaining 11 APAs (25%) coursed along the lateral aspect of the prostate, termed lateral APAs. All APAs originated from the internal obturator artery and iliac artery or a branch of the iliac artery such as the inferior vesical artery. The majority of apical APAs arose from the internal obturator artery (84%). Seven patients (19%) had multiple APAs. APAs are more frequently detected by the use of MDCT angiography than as suggested by previous surgical studies. The identification of APAs on MDCT angiography may provide useful information for the surgical preservation of APAs during a laparoscopic or robot-assisted radical prostatectomy

  7. Deciphering the Mechanism of Alternative Cleavage and Polyadenylation in Mantle Cell Lymphoma (MCL)

    Science.gov (United States)

    2015-12-01

    event. The discovery that transformed and rapidly proliferating cells use alternative cleavage and polyadenylation ( APA ) to shorten the 3´UTR of their... APA . However, the mechanism that APA is still unknown. The goal of this project is to identify the mechanism of cyclin D1 APA regulation in cancer...for APA in MCL. In addition, by using RNA Seq. CFIm25 has been identified as an important global regulator of shortening of cyclin D1 mRNA and other

  8. Longitudinal behavior of autoimmune GH deficiency: from childhood to transition age.

    Science.gov (United States)

    De Bellis, Annamaria; Bellastella, Giuseppe; Maiorino, Maria Ida; Aitella, Ernesto; Lucci, Emma; Cozzolino, Domenico; Bellastella, Antonio; Bizzarro, Antonio; Giugliano, Dario; Esposito, Katherine

    2016-03-01

    Some cases of apparently idiopathic GH deficiency (GHD) may be caused by pituitary autoimmunity. To study the variations in pituitary function and antipituitary antibodies (APA) from childhood to transition age in patients with apparently idiopathic GHD. We conducted a longitudinal study. Pituitary function and APA detection by immunofluorescence were investigated in 24 childhood patients with isolated GHD before starting recombinant GH therapy and after the stopping of this therapy in transition age. Sera of patients positive for APA were processed by double immunofluorescence to identify their pituitary target. At diagnosis, 16 out of 24 patients were APA positive targeting only somatotrophs (group 1), while the remaining eight were APA negative (group 2). When retested off therapy, 12 out of 16 patients in group 1 persisted being APA positive, while the remaining four became negative with recovery of pituitary function. All patients in group 2 persisted being APA negative but still showing GHD. Of the 12 patients persistently APA positive, eight with confirmed GHD showed APA still targeting somatotrophs, whereas four showed APA targeting only gonadotrophs associated with isolated hypogonadotropic hypogonadism (HH). Patients with APA at middle but not at high titer in childhood may show a remission of autoimmune GHD in childhood after GH replacement therapy. As APA may shift their target in transition period, an early characterization of APA by double immunofluorescence is advisable in APA positive GHD patients showing delayed puberty, to allow an early diagnosis and an appropriate therapy, thus preventing the progression toward HH. © 2016 European Society of Endocrinology.

  9. Gonadotropin-Releasing Hormone Stimulate Aldosterone Production in a Subset of Aldosterone-Producing Adenoma

    Science.gov (United States)

    Kishimoto, Rui; Oki, Kenji; Yoneda, Masayasu; Gomez-Sanchez, Celso E.; Ohno, Haruya; Kobuke, Kazuhiro; Itcho, Kiyotaka; Kohno, Nobuoki

    2016-01-01

    Abstract We aimed to detect novel genes associated with G protein-coupled receptors (GPCRs) in aldosterone-producing adenoma (APA) and elucidate the mechanisms underlying aldosterone production. Microarray analysis targeting GPCR-associated genes was conducted using APA without known mutations (APA-WT) samples (n = 3) and APA with the KCNJ5 mutation (APA-KCNJ5; n = 3). Since gonadotropin-releasing hormone receptor (GNRHR) was the highest expression in APA-WT by microarray analysis, we investigated the effect of gonadotropin-releasing hormone (GnRH) stimulation on aldosterone production. The quantitative polymerase chain reaction assay results revealed higher GNRHR expression levels in APA-WT samples those in APA-KCNJ5 samples (P APA-WT samples, and there was a significant and positive correlation between GNRHR and LHCGR expression in all APA samples (r = 0.476, P APA-WT (n = 9), which showed higher GNRHR and LHCGR levels, had significantly higher GnRH-stimulated aldosterone response than those with APA-KCNJ5 (n = 13) (P APA-WT, and the molecular analysis including the receptor expression associated with clinical findings of GnRH stimulation. PMID:27196470

  10. 78 FR 32991 - Medicaid Program; Increased Federal Medical Assistance Percentage Changes Under the Affordable...

    Science.gov (United States)

    2013-06-03

    ... take effect in accordance with section 553(b) of the Administrative Procedure Act (APA) (5 U.S.C. 553(b... incorporates a statement of the finding and the reasons therefore in the notice. Section 553(d) of the APA...

  11. 77 FR 40805 - Federal Pell Grant Program; Correction

    Science.gov (United States)

    2012-07-11

    ... Date with the following two paragraphs: The Administrative Procedure Act (APA) generally requires that... reduced amounts of Pell Grant funds, there is good cause to waive the delayed effective dates in the APA...

  12. 78 FR 54248 - Notice of Public Meeting of the Interagency Steering Committee on Radiation Standards

    Science.gov (United States)

    2013-09-03

    ... reference in the development of proposals under the Administrative Procedure Act (APA) for changes to... APA process for notice and comment. Presentations of previous ISCORS public meetings are available at...

  13. 77 FR 29235 - Patient Protection and Affordable Care Act; Standards Related to Reinsurance, Risk Corridors, and...

    Science.gov (United States)

    2012-05-17

    ... effect in accordance with section 553(b) of the Administrative Procedure Act (APA) (5 U.S.C. 553(b... incorporates a statement of the finding and the reasons therefore in the notice. Section 553(d) of the APA...

  14. 78 FR 79285 - Home Mortgage Disclosure (Regulation C): Adjustment to Asset-Size Exemption Threshold

    Science.gov (United States)

    2013-12-30

    ... Requirements Administrative Procedure Act Under the Administrative Procedure Act (APA), notice and opportunity... 553(d) of the APA generally requires publication of a final rule not less than 30 days before its...

  15. 78 FR 79619 - Patient Protection and Affordable Care Act; Program Integrity: Exchange, Premium Stabilization...

    Science.gov (United States)

    2013-12-31

    ... with section 553(b) and (c) of the Administrative Procedure Act (APA) (5 U.S.C. 553(b) & (c)). However... the finding and the reasons therefor in the notice. Section 553(d) of the APA ordinarily requires a 30...

  16. What Is Psychiatry?

    Medline Plus

    Full Text Available ... Foundation APA Learning Center APA Annual Meeting Psychiatric News PsychiatryOnline Workplace Mental Health Terms of Use Copyright Contact © 2018 American Psychiatric Association. All Rights Reserved. 800 Maine ...

  17. Asian and Pacific American Exceptional Children. A Conversation.

    Science.gov (United States)

    Decano, Pio

    1979-01-01

    Presented in the format of an imaginary dialogue between seven educators of Asian and Pacific American (APA) backgrounds, the article addresses some issues and concerns in the training of special education personnel to work with APA handicapped children. (DLS)

  18. What Is Psychiatry?

    Science.gov (United States)

    ... APA's Diagnostic and Statistical Manual of Mental Disorders ( DSM-5 ), which contains descriptions, symptoms and other criteria for ... is ECT? What is Telepsychiatry? Your Guide to DSM-5 Patient/Families Become an APA Member Learn More ...

  19. What Is Psychiatry?

    Medline Plus

    Full Text Available ... APA's Diagnostic and Statistical Manual of Mental Disorders ( DSM-5 ), which contains descriptions, symptoms and other criteria for ... is ECT? What is Telepsychiatry? Your Guide to DSM-5 Patient/Families Become an APA Member Learn More ...

  20. Learn to manage your anger

    Science.gov (United States)

    ... website. Controlling anger before it controls you. www.apa.org/topics/anger/control.aspx . Accessed October 13, ... a psychologist can help you manage anger. www.apa.org/topics/anger/help.aspx . Accessed October 13, ...

  1. What Is Psychiatry?

    Medline Plus

    Full Text Available ... APA's Diagnostic and Statistical Manual of Mental Disorders ( DSM-5 ), which contains descriptions, symptoms and other criteria ... is ECT? What is Telepsychiatry? Your Guide to DSM-5 Patient/Families Become an APA Member Learn ...

  2. What Is Psychiatry?

    Medline Plus

    Full Text Available ... APA Foundation APA Annual Meeting Psychiatric News PsychiatryOnline Workplace Mental Health Sign In Join General Residents and Fellows Medical Students International close menu Psychiatrists Education Practice Cultural Competency Awards & Leadership Opportunities Advocacy & APAPAC ...

  3. 78 FR 49555 - Special Opportunities Fund, Inc.; Notice of Application

    Science.gov (United States)

    2013-08-14

    ... the Administrative Procedure Act of 1946 (``APA'') concerning a proxy voting procedure under Section... order under Section 554(e) of the APA declaring that applicant's proxy voting procedure does not satisfy... Procedure''). SPE requests a declaratory order pursuant to Section 554(e) of the APA stating that the Voting...

  4. 77 FR 64908 - Extension of Administrative Stay; Approval and Promulgation of Implementation Plans; New Mexico...

    Science.gov (United States)

    2012-10-24

    ... the Administrative Procedure Act (APA). EPA previously stayed this rule for 90 days, from July 16... Pursuant to section 705 of the APA, the EPA hereby extends the existing administrative stay of the... obligations under the terms of the NM FIP that arise during the 135 day period. Under section 705 of the APA...

  5. 77 FR 41697 - Stay of the Effectiveness of Requirements; Approval and Promulgation of Implementation Plans; New...

    Science.gov (United States)

    2012-07-16

    ... Procedure Act (APA) for 90 days. Today's action reflects this stay in the Code of Federal Regulations. DATES... FIP Rule Pursuant to section 705 of the APA, the EPA hereby stays the effectiveness of the NM FIP Rule... the terms of the NM FIP that arise during the 90 day period. Under section 705 of the APA, ``an agency...

  6. 77 FR 30241 - Representation Procedures and Rulemaking Authority

    Science.gov (United States)

    2012-05-22

    ... the informal rulemaking procedures in the Administrative Procedure Act (APA), 5 U.S.C. 553, and... stricter requirements in sections 556 and 557 of the APA, this hearing will comply with those informal rulemaking procedures under the APA. See, e.g. United States v. Allegheny-Ludlum Steel Corp., 406 US 742...

  7. 77 FR 40525 - Dependency and Indemnity Compensation (DIC) Benefits for Survivors of Former Prisoners of War...

    Science.gov (United States)

    2012-07-10

    ... Administrative Procedure Act (APA), that this final rule merely incorporates statutory provisions. Therefore, the procedures of the APA regarding notice of proposed rulemaking and opportunities for public participation are..., this final rule is exempt from the APA's 30-day delayed effective date requirement. Paperwork Reduction...

  8. Ensuring the Availability and Quality of School Psychology Doctoral Internships

    Science.gov (United States)

    Harris, Abigail M.

    2015-01-01

    Currently, only a small percentage of internships accredited by the American Psychological Association (APA) are filled by school psychology interns and only a few of the available APA internship positions are in schools. Program data submitted online to APA indicate that many interns are in sites that meet the guidelines adopted by the Council of…

  9. 77 FR 23128 - Rules Governing Hearings Before the Agency of Original Jurisdiction and the Board of Veterans...

    Science.gov (United States)

    2012-04-18

    ... Administrative Procedure Act (APA). DATES: This rule is effective June 18, 2012, without further notice, unless... should have followed the notice-and-comment procedure of 5 U.S.C. 553(b) and (c) of the APA. Accordingly... section 553 of the APA (5 U.S.C. 553). Comments that are frivolous, insubstantial, or outside the scope of...

  10. 78 FR 37132 - Approval and Promulgation of Implementation Plans; Revised Format for Materials Being...

    Science.gov (United States)

    2013-06-20

    ... the ``good cause'' exemption in section 553(b)(3)(B) of the Administrative Procedure Act (APA) which... recodification and miscellaneous revisions to the Florida SIP. EPA also finds that there is good cause under APA.... Section 553(d)(3) of the APA allows an effective date less than 30 days after publication ``as otherwise...

  11. 77 FR 27626 - Approval and Promulgation of Implementation Plans; Commonwealth of Kentucky; Regional Haze State...

    Science.gov (United States)

    2012-05-11

    ... section 553(b)(3)(B) of the Administrative Procedure Act (APA) which, upon finding ``good cause... related to the regional haze SIP revisions. EPA also finds that there is good cause under APA section 553...(d)(3) of the APA allows an effective date less than 30 days after publication ``as otherwise...

  12. 78 FR 22788 - Supplemental Determination for Renewable Fuels Produced Under the Final RFS2 Program From Grain...

    Science.gov (United States)

    2013-04-17

    ... Procedure Act (APA), 5 U.S.C. 553(b)(B), provides that, when an agency for good cause finds that notice and... (A) or (B) of section 553(b) of the APA. Specifically, EPA is correcting the final rule to indicate... omitted from the final rule. EPA also finds that there is good cause under APA section 553(d)(3) for these...

  13. 78 FR 57798 - Program Integrity Issues

    Science.gov (United States)

    2013-09-20

    ... Act (APA) (5 U.S.C. 553), the Department generally offers interested parties the opportunity to comment on proposed regulations. However, the APA provides that an agency is not required to conduct...). There is good cause here for waiving rulemaking under the APA. Notice and comment to amend current Sec...

  14. 78 FR 77563 - Technical Amendments

    Science.gov (United States)

    2013-12-24

    ... Administrative Procedure Act (APA) requires a federal agency to provide the public with notice and the... unions. The APA permits an agency to forego the notice and comment period under certain circumstances... and public comment are unnecessary under section 553(b)(3)(B) of the APA.\\6\\ NCUA also finds good...

  15. 78 FR 49975 - Energy Conservation Program for Consumer Products: Landmark Legal Foundation; Petition for...

    Science.gov (United States)

    2013-08-16

    ....doe.gov . SUPPLEMENTARY INFORMATION: The Administrative Procedure Act (APA), 5 U.S.C. 551 et seq... violates the Administrative Procedure Act's (APA) and Executive Order 13563's tenets of transparency... Petition for Reconsideration. However, the egregious violations of the APA as documented in this Petition...

  16. 77 FR 32407 - Medicare Program; Changes to the Medicare Advantage and the Medicare Prescription Drug Benefit...

    Science.gov (United States)

    2012-06-01

    ... with section 553(b) of the Administrative Procedure Act (APA) (5 U.S.C. 553(b)). However, we can waive... the finding and the reasons therefore in the notice. Section 553(b) of the APA ordinarily requires a... constitute a rulemaking that would be subject to the APA notice and comment or delayed effective date...

  17. 78 FR 72033 - Approval and Promulgation of Implementation Plans; Florida: General Requirements and Gasoline...

    Science.gov (United States)

    2013-12-02

    ... in section 553(b)(3)(B) of the Administrative Procedure Act (APA) which, upon finding ``good cause.... EPA also finds that there is good cause under APA section 553(d)(3) for this correction to become effective on the date of publication of this action. Section 553(d)(3) of the APA allows an effective date...

  18. 78 FR 33045 - Revocation of Statement of Policy on Public Participation in Rule Making

    Science.gov (United States)

    2013-06-03

    ...) that requires agencies in USDA to follow the Administrative Procedure Act's (APA) notice-and-comment rulemaking procedures even in situations where the APA does not require it. The Statement of Policy... Congress to amend the APA to remove the exemption from the notice-and-comment requirement for rulemakings...

  19. 78 FR 16783 - Approval and Promulgation of Implementation Plans; Georgia; Control Techniques Guidelines and...

    Science.gov (United States)

    2013-03-19

    ... Administrative Procedure Act (APA) which, upon finding ``good cause,'' authorizes agencies to dispense with... action addressing approval of the Georgia RACT rules. EPA also finds that there is good cause under APA.... Section 553(d)(3) of the APA allows an effective date less than 30 days after publication ``as otherwise...

  20. 78 FR 64194 - Revocation of Statement of Policy on Public Participation in Rulemaking

    Science.gov (United States)

    2013-10-28

    ... the Administrative Procedure Act's (APA) notice-and-comment rulemaking procedures in situations where the APA does not require it. The Statement of Policy implemented a 1969 recommendation by the Administrative Conference of the United States (ACUS), which urged Congress to amend the APA to remove the...

  1. 78 FR 54756 - Extension of Expiration Dates for Two Body System Listings

    Science.gov (United States)

    2013-09-06

    ... Justification for Final Rule We follow the Administrative Procedure Act (APA) rulemaking procedures specified in.... 902(a)(5). Generally, the APA requires that an agency provide prior notice and opportunity for public comment before issuing a final regulation. The APA provides exceptions to the notice-and-comment...

  2. 78 FR 15882 - Medicare Program; Hospital Inpatient Prospective Payment Systems for Acute Care Hospitals and the...

    Science.gov (United States)

    2013-03-13

    ... effect in accordance with section 553(b) of the Administrative Procedure Act (APA) (5 U.S.C. 553(b... incorporates a statement of the finding and the reasons therefore in the notice. Section 553(b) of the APA..., this correcting document does not constitute a rulemaking that would be subject to the APA notice and...

  3. 77 FR 71687 - Federal Employees' Group Life Insurance Program: Court Orders Prior to July 22, 1998

    Science.gov (United States)

    2012-12-04

    ... preliminarily approved by the Court. Under Section 553(b) of the Administrative Procedure Act (APA) (5 U.S.C... interest. In addition, the APA exempts interpretative rules from proposed rulemaking procedures. This rule... asserts that good cause exists to implement this rule as an interim rule under the APA, 5 U.S.C. 553(b...

  4. 78 FR 60766 - Clarification on Fireworks Policy Regarding Approvals or Certifications for Specialty Fireworks...

    Science.gov (United States)

    2013-10-02

    ... requirements in the APA Standard 87-1, and pass a thermal stability test. Instead of applying to PHMSA, the manufacturer may apply in writing to an FCA with the information required in the APA Standard 87-1. After....64 or 173.65, the APA Standard 87-1 and the requirements below. \\2\\ An example of a specialty...

  5. 77 FR 9865 - Clarification on the Division 1.1 Fireworks Approvals Policy

    Science.gov (United States)

    2012-02-21

    ... APA Standard 87-1 (IBR, see Sec. 171.7), and the device passes the thermal stability test. Additionally, the applicant must certify that the firework device conforms to the APA Standard 87-1 and that... approval. While APA Standard 87-1 contains two instances where Division 1.1 fireworks may be approved under...

  6. 77 FR 24397 - Approval and Promulgation of Implementation Plans: Georgia; Approval of Substitution for...

    Science.gov (United States)

    2012-04-24

    ... Administrative Procedures Act (APA) which, upon finding ``good cause,'' authorizes agencies to dispense with... 30-day delayed effective date otherwise provided for in the APA). DATES: This action is effective... in the section 553(b)(3)(B) of the APA which, upon finding ``good cause,'' authorizes agencies to...

  7. 78 FR 77122 - Proposed Modification of a General NPDES Permit for Small Suction Dredging-Permit Number IDG-37-0000

    Science.gov (United States)

    2013-12-20

    ... required by section 553 of the Administrative Procedure Act (APA), or any other law, to publish general... entities.'' EPA has concluded that NPDES general permits are permits, not rulemakings, under the APA and thus not subject to APA rulemaking requirements or the RFA. Notwithstanding that general permits are...

  8. 77 FR 36149 - Disclosure Requirements and Prohibitions Concerning Franchising

    Science.gov (United States)

    2012-06-18

    ... unnecessary under the Administrative Procedure Act (APA) for the same reason. The Commission, therefore, has omitted notice and comment for good cause as provided by section 553(b)(B) of the APA.\\10\\ For this reason... analyses required where the APA does not require public comment). List of Subjects in 16 CFR Part 436...

  9. 78 FR 79436 - Boulder Canyon Project-Post-2017 Resource Pool

    Science.gov (United States)

    2013-12-30

    ... accordance with the HPAA, Western allocated portions of Schedule D to the Arizona Power Authority (APA) and... energy from APA or CRC will not be eligible for an allocation as a new allottee. Comment: If there is... the APA, would those arrangements be sufficient to meet any load aggregation requirements? Response...

  10. The Value of Peer Feedback Opportunities for Students in Writing Intensive Classes

    Science.gov (United States)

    Kennette, Lynne N.; Frank, Nichole M.

    2013-01-01

    The present study was conducted to examine the usefulness of peer feedback on APA-style research papers in a writing-intensive class. Subsequent to APA training, students were asked to review and provide feedback on a classmate's APA-style research report for both content and formatting. Performance on this research report was then compared to…

  11. 78 FR 46498 - Delegation of Authority to Director of the Division of Enforcement

    Science.gov (United States)

    2013-08-01

    ...: The Commission finds, in accordance with the Administrative Procedure Act (``APA'') 5 U.S.C. 553(b)(3... relate to a substantive rule. Accordingly, the provisions of the APA regarding notice of rulemaking..., which apply only when notice and comment are required by the APA or other law, 5 U.S.C. 603, are not...

  12. 77 FR 429 - Clarification and Further Guidance on the Fireworks Approvals Policy

    Science.gov (United States)

    2012-01-05

    ...) and the American Pyrotechnic Association (APA) Standard 87-1. PHMSA understands that it is a common... approval is requested conforms to the APA Standard 87-1, and the descriptions and technical information... manufacturer must sign and certify that the device for which the approval is requested conforms to the APA...

  13. 78 FR 68782 - Public Meeting on the Improve Tracking of Workplace Injuries and Illnesses Proposed Rule

    Science.gov (United States)

    2013-11-15

    ... notice and comments requirements in the Administrative Procedure Act (APA) (5 U.S.C. 553) rather than... health standards. Section 553 of the APA, which governs this proposal, does not require a public hearing... presentation'' (5 U.S.C. 553(c)) (emphasis added). To promulgate a proposed regulation, the APA requires the...

  14. 78 FR 42457 - Hazardous Materials: Revision to Fireworks Regulations (RRR)

    Science.gov (United States)

    2013-07-16

    ... apply to an FCA to review and certify that Division 1.4G consumer fireworks comply with APA Standard 87... whether the device meets the requirements of APA Standard 87-1 and matches the dimensions, chemical... applicant's procedures to determine whether they are adequate to certify compliance with APA Standard 87-1...

  15. 77 FR 70687 - Approval and Promulgation of Implementation Plans; Florida; Section 128 and 110(a)(2)(E)(ii) and...

    Science.gov (United States)

    2012-11-27

    ... Administrative Procedure Act (APA) which, upon finding ``good cause,'' authorizes agencies to dispense with... NAAQS into the Florida SIP. EPA also finds that there is good cause under APA section 553(d)(3) for this correction to become effective on the date of publication of this action. Section 553(d)(3) of the APA allows...

  16. 78 FR 67307 - Approval and Promulgation of Implementation Plans; Tennessee; Infrastructure Requirements for the...

    Science.gov (United States)

    2013-11-12

    ...'' exemption in section 553(b)(3)(B) of the Administrative Procedure Act (APA) which, upon finding ``good cause.... EPA also finds that there is good cause under APA section 553(d)(3) for this correction to become effective on the date of publication of this action. Section 553(d)(3) of the APA allows an effective date...

  17. 77 FR 25717 - Proposed Issuance of a General NPDES Permit for Small Suction Dredging

    Science.gov (United States)

    2012-05-01

    ... required by section 553 of the Administrative Procedure Act (APA), or any other law, to publish general... entities.'' EPA has concluded that NPDES general permits are permits, not rulemakings, under the APA and thus not subject to APA rulemaking requirements or the RFA. Notwithstanding that general permits are...

  18. 78 FR 26690 - Hours of Service (HOS) of Drivers; Application for Renewal and Expansion of American Pyrotechnics...

    Science.gov (United States)

    2013-05-07

    ... Association (APA) Exemption From the 14-Hour Rule During Independence Day Celebrations AGENCY: Federal Motor... exemption; request for comments. SUMMARY: The American Pyrotechnics Association (APA) has requested a renewal of its exemption for 48 APA member-companies from FMCSA's regulation that drivers of commercial...

  19. 77 FR 213 - United States Savings Bonds, Series EE and I

    Science.gov (United States)

    2012-01-04

    ... (APA). Because this rule relates to United States securities, which are contracts between Treasury and the owner of the security, this rule falls within the contract exception to the APA, 5 U.S.C. 553(a)(2). As a result, the notice, public comment, and delayed effective date provisions of the APA are...

  20. 78 FR 4029 - Treasury Tax and Loan Depositaries; Depositaries and Financial Agents of the Government

    Science.gov (United States)

    2013-01-18

    ... Administrative Procedure Act (APA) requires a federal agency to provide the public with notice and the.... They make minor changes which are statutorily required by the Dodd-Frank Act. The APA permits an agency... under section 553(b)(3)(B) of the APA.\\3\\ NCUA also finds good cause to dispense with the 30-day delayed...

  1. 78 FR 39057 - Hours of Service of Drivers; Renewal and Expansion of American Pyrotechnics Association Exemption...

    Science.gov (United States)

    2013-06-28

    ... Association (APA) from FMCSA's regulation prohibiting drivers of commercial motor vehicles (CMVs) from driving after the 14th hour after coming on duty. The FMCSA renews the exemption for 45 APA member-companies and... carrier is being denied. Additionally, the APA advised FMCSA of the removal from the original renewal...

  2. 77 FR 33634 - U.S. Treasury Securities-State and Local Government Series

    Science.gov (United States)

    2012-06-07

    ..., dated September 30, 1993. Administrative Procedure Act (APA). Because this rule relates to United States... contract exception to the APA, 5 U.S.C. 553(a)(2). As a result, the notice, public comment, and delayed effective date provisions of the APA are inapplicable to this rule. Regulatory Flexibility Act. The...

  3. 78 FR 21517 - Practices and Procedures

    Science.gov (United States)

    2013-04-11

    ... Administrative Procedure Act (APA). However, an exemption from notice and comment rulemaking requirements exists... the use of APA notice and comment procedures impracticable. The ``unnecessary'' prong of the agency's... this amendment from the normal APA notice-and-comment procedures. The public interest prong of the good...

  4. Wood Products Consumption for Industrial Markets in the United States, Testing a New Research Method

    Science.gov (United States)

    Craig Adair; David B. McKeever

    2013-01-01

    In early 2012, APA-The Engineered Wood Association conducted studies of three industries: institutional furniture, motor homes, and travel trailers and campers. The survey procedure was the same as that used by APA for many years. Lists of individual manufacturers were purchased, a telephone interviewing company was hired to administer a questionnaire, and APA...

  5. 78 FR 60763 - Clarification on Fireworks Policy Regarding Approvals or Certifications for Firework Series

    Science.gov (United States)

    2013-10-02

    ... 49 CFR 173.64 or 173.65, and the American Pyrotechnic Association (APA) Standard 87-1, Version 2001... still must conform to the requirements in the APA Standard 87-1, and pass a thermal stability test... required in APA Standard 87-1. After reviewing the application, the FCA will notify the manufacturer, in...

  6. 78 FR 40163 - Notice of Availability of the Draft Environmental Impact Statement for the TransWest Express 600...

    Science.gov (United States)

    2013-07-03

    ... Alternative (APA) transmission route in the DEIS. The rationale for selecting the location of this alternative... specific to the 760-mile- long APA. The requested ROW width would generally be 250 feet. As a general planning goal, the APA has been located parallel to existing transmission lines and other utilities, within...

  7. 77 FR 65495 - Medicare Program; Hospital Inpatient Prospective Payment Systems for Acute Care Hospitals and the...

    Science.gov (United States)

    2012-10-29

    ... effect in accordance with section 553(b) of the Administrative Procedure Act (APA) (5 U.S.C. 553(b... incorporates a statement of the finding and the reasons therefore in the notice. Section 553(d) of the APA... document does not constitute a rule that would be subject to the APA notice and comment or delayed...

  8. 77 FR 4908 - Medicare Program; Hospital Inpatient Prospective Payment Systems for Acute Care Hospitals and the...

    Science.gov (United States)

    2012-02-01

    ... with section 553(b) of the Administrative Procedure Act (APA) (5 U.S.C. 553(b)). However, we can waive... the finding and the reasons therefore in the notice. Section 553(b) of the APA ordinarily requires a... document does not constitute a rulemaking that would be subject to the APA notice and comment or delayed...

  9. 78 FR 39613 - Federal Pell Grant Program

    Science.gov (United States)

    2013-07-02

    ... format (e.g., braille, large print, audiotape, or compact disc) on request to the program contact person... regulations in accordance with the Administrative Procedure Act (APA) (5 U.S.C. 553). However, the APA... rulemaking under the APA because the statutory change to prohibit a student from receiving two Federal Pell...

  10. What Is Psychiatry?

    Medline Plus

    Full Text Available ... APA Foundation APA Annual Meeting Psychiatric News PsychiatryOnline Workplace Mental Health Sign In Join General Residents and ... Learning Center APA Annual Meeting Psychiatric News PsychiatryOnline Workplace Mental Health Terms of Use Copyright Contact © 2018 ...

  11. 2010 Annual Report of the American Psychological Association

    Science.gov (United States)

    American Psychologist, 2011

    2011-01-01

    This report presents the 2010 annual report of the American Psychological Association (APA). It provides the highlights of the association's and individual directorate's activities to APA members. APA continued its efforts to advance psychological practice and ensure the public's access to high-quality psychological services, apply psychological…

  12. 76 FR 28168 - Securities of Nonmember Insured Banks

    Science.gov (United States)

    2011-05-16

    .... Administrative Procedure Act Pursuant to the Administrative Procedure Act (APA), 5 U.S.C. 553(b)(B), the FDIC... good cause exception provided for in section 553(b)(B) of the APA applies to the Final Rule. Section 553(d)(3) of the APA provides that the publication of a rule shall be made not less than 30 days...

  13. 75 FR 49820 - Delegation of Authority to the Director of Its Division of Enforcement

    Science.gov (United States)

    2010-08-16

    ... the Administrative Procedure Act (``APA'') (5 U.S.C. 553(b)(3)(A)), that this amendment relates solely..., the provisions of the APA regarding notice of the proposed rulemaking, opportunities for public..., which apply only when notice and comment are required by the APA or other law, 5 U.S.C. 603, are not...

  14. 76 FR 39769 - Delegation of Authority to the Director of Its Division of Enforcement

    Science.gov (United States)

    2011-07-07

    ... finds, in accordance with the Administrative Procedure Act (``APA'') (5 U.S.C. 553(b)(3)(A)), that this... rule. Accordingly, the provisions of the APA regarding notice of the proposed rulemaking, opportunities... Flexibility Act, which apply only when notice and comment are required by the APA or other law, 5 U.S.C. 603...

  15. 76 FR 80226 - Technical Amendments

    Science.gov (United States)

    2011-12-23

    ... final rule, effective upon publication. Generally, the Administrative Procedure Act (APA) requires a.... Additionally, the APA requires that a final rule must have a delayed effective date of 30 days from the date of... delayed effective date requirement under the APA. 5 U.S.C. 553(d)(3). Again the technical change conforms...

  16. 76 FR 59769 - Clarification on the Division 1.1 Fireworks Approvals Policy

    Science.gov (United States)

    2011-09-27

    ... test laboratory if the firework device is manufactured in accordance with APA Standard 87-1 (IBR, see... certify that the firework device conforms to the APA Standard 87-1 and that the descriptions and technical... issuing the EX approval. While APA Standard 87-1 references two instances where Division 1.1 fireworks may...

  17. 76 FR 43111 - Regulation Z; Truth in Lending

    Science.gov (United States)

    2011-07-20

    ... Procedures Act (APA), 5 U.S.C. 551 et seq., generally requires public notice before promulgation of..., however, the APA also provides exceptions ``for interpretative rules'' and ``when the agency for good... the public interest.'' 5 U.S.C. 553(b)(A) and (B). The APA also requires that rules generally be...

  18. American Psychological Association: Annual Report, 2008

    Science.gov (United States)

    American Psychologist, 2009

    2009-01-01

    This article presents the 2008 annual reports from the various directorates and offices of the American Psychological Association (APA). In 2008, APA continued to work on initiatives, programs, and products that lend value to the member's psychology career, support the future of their discipline, and serve the public. APA's goal is to strengthen…

  19. Rwandan Journal of Education: Submissions

    African Journals Online (AJOL)

    Style: For referencing style, authors must follow guidelines in the latest edition of the American Psychological Association (APA) guidelines (http://www.apa.org), and paginate all text at the centre bottom of each page. Examples of APA Bibliography: Abd-Kadir, J., & Hardman F. (2007). The discourse of whole class teaching: ...

  20. What Is Psychiatry?

    Medline Plus

    Full Text Available ... APA Foundation APA Annual Meeting Psychiatric News PsychiatryOnline Workplace Mental Health Sign In Join General Residents and Fellows Medical ... Learning Center APA Annual Meeting Psychiatric News PsychiatryOnline Workplace Mental Health Terms of Use Copyright Contact © 2018 American Psychiatric ...

  1. Recurrent Pregnancy Loss

    Directory of Open Access Journals (Sweden)

    Véronique Piroux

    1997-01-01

    Full Text Available Antiphospholipid antibodies (APA are associated with thrombosis, thrombocytopenia and fetal loss but they occur in a variety of diseases. Despite many efforts, a correlation between the specificity of particular subgroups of APA and particular clinical situations remains to be established. The antigens at the origin of APA remain to be identified. We discuss here the possible links between cell apoptosis or necrosis, leading to plasma membrane alterations, and the occurrence of APA in response to sustained stimulation. The pathogenic potential of APA is also considered with respect to recurrent pregnancy loss.

  2. Genome-wide dynamics of alternative polyadenylation in rice

    Science.gov (United States)

    Fu, Haihui; Yang, Dewei; Su, Wenyue; Ma, Liuyin; Shen, Yingjia; Ji, Guoli; Ye, Xinfu; Wu, Xiaohui

    2016-01-01

    Alternative polyadenylation (APA), in which a transcript uses one of the poly(A) sites to define its 3′-end, is a common regulatory mechanism in eukaryotic gene expression. However, the potential of APA in determining crop agronomic traits remains elusive. This study systematically tallied poly(A) sites of 14 different rice tissues and developmental stages using the poly(A) tag sequencing (PAT-seq) approach. The results indicate significant involvement of APA in developmental and quantitative trait loci (QTL) gene expression. About 48% of all expressed genes use APA to generate transcriptomic and proteomic diversity. Some genes switch APA sites, allowing differentially expressed genes to use alternate 3′ UTRs. Interestingly, APA in mature pollen is distinct where differential expression levels of a set of poly(A) factors and different distributions of APA sites are found, indicating a unique mRNA 3′-end formation regulation during gametophyte development. Equally interesting, statistical analyses showed that QTL tends to use APA for regulation of gene expression of many agronomic traits, suggesting a potential important role of APA in rice production. These results provide thus far the most comprehensive and high-resolution resource for advanced analysis of APA in crops and shed light on how APA is associated with trait formation in eukaryotes. PMID:27733415

  3. 2015 Annual Report of the American Psychological Association.

    Science.gov (United States)

    2016-01-01

    Presents the 2015 Annual Report of the American Psychological Association. In his introduction, President Barry Anton describes how 2015 was among APA's most challenging. Although 2015 ushered in an era of greater transparency within the association and enhanced communications to members and the public, it also required painful self-reflection stemming from the revelations of an independent review by an outside law firm. The review examined the question of whether APA played any role related to the Bush administration's use of abusive interrogation techniques during the war on terror. Anton's introduction also discusses (1) the APA convention, (2) representing APA at a White House meeting with health care providers and insurance companies, (3) APA's effort to increase the number of APA-accredited internships, (4) international activities, and (5) the global summit on psychology and integrated care. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  4. Longitudinal assessment of the impact of adapted physical activity on upper limb disability and quality of life in breast cancer survivors from an Italian cohort.

    Science.gov (United States)

    Mirandola, Daniela; Miccinesi, Guido; Muraca, Maria Grazia; Belardi, Stefania; Giuggioli, Roberta; Sgambati, Eleonora; Manetti, Mirko; Monaci, Marco; Marini, Mirca

    2018-02-01

    The purpose of this study was to evaluate the effectiveness of a specific adapted physical activity (APA) protocol on upper limb disability and quality of life in breast cancer survivors and to assess longitudinally the possible role of APA on long-term benefits. Breast cancer survivors from an Italian cohort were assessed by fitness tests (shoulder-arm mobility, range of motion, and back flexibility) before and after 8-week APA. Quality of life and back and surgical shoulder pain intensity were evaluated by Short Form-12 and numerical rating scale questionnaires, respectively. At 1.5-year post-APA follow-up, survivors were evaluated as at baseline/post-APA to assess long-term effects. A statistically significant improvement in shoulder-arm mobility, pain perception, and quality of life was observed in breast cancer survivors after APA intervention. Longitudinal analyses indicated an overall decrease in the achieved benefits at 1.5-year post-APA. The survivorship phase of breast cancer requires a multidisciplinary collaboration involving either the cancer-care medical team or APA professionals to manage psychophysical outcomes. A specific APA protocol may represent an effective countermeasure to reduce post-treatment upper limb disability and improve the quality of life in breast cancer survivors. Participation in structured APA protocols should be maintained over time to preserve the achieved benefits.

  5. Single Nucleotide Polymorphisms Can Create Alternative Polyadenylation Signals and Affect Gene Expression through Loss of MicroRNA-Regulation

    Science.gov (United States)

    Thomas, Laurent F.; Sætrom, Pål

    2012-01-01

    Alternative polyadenylation (APA) can for example occur when a protein-coding gene has several polyadenylation (polyA) signals in its last exon, resulting in messenger RNAs (mRNAs) with different 3′ untranslated region (UTR) lengths. Different 3′UTR lengths can give different microRNA (miRNA) regulation such that shortened transcripts have increased expression. The APA process is part of human cells' natural regulatory processes, but APA also seems to play an important role in many human diseases. Although altered APA in disease can have many causes, we reasoned that mutations in DNA elements that are important for the polyA process, such as the polyA signal and the downstream GU-rich region, can be one important mechanism. To test this hypothesis, we identified single nucleotide polymorphisms (SNPs) that can create or disrupt APA signals (APA-SNPs). By using a data-integrative approach, we show that APA-SNPs can affect 3′UTR length, miRNA regulation, and mRNA expression—both between homozygote individuals and within heterozygote individuals. Furthermore, we show that a significant fraction of the alleles that cause APA are strongly and positively linked with alleles found by genome-wide studies to be associated with disease. Our results confirm that APA-SNPs can give altered gene regulation and that APA alleles that give shortened transcripts and increased gene expression can be important hereditary causes for disease. PMID:22915998

  6. Preparation and microscopy examination of alginate-poly-L-lysine-alginate microcapsules.

    Science.gov (United States)

    Fu, Hong-Xing; Li, Hui; Wu, Lan-Lan; Zhao, Ying-Zheng; Xu, Yan-Yan; Zhu, Yan-Lin; Xue, Shen-Liu; Wang, Da-Wang; Liu, Cheng-Yang; Yang, Shu-Lin; Li, Xiao-Kun

    2014-11-01

    Ca-alginate-poly-l-lysine-alginate (APA-Ca) and Ba-alginate-poly-l-lysine-alginate (APA-Ba) microcapsules were prepared and their thickness and surface were examined by light microscopy and scanning electron microscopy. Specifically, light microscopy with frozen section was used to visualize and quantify the thickness of APA membrane, and monitor temporal changes in the thickness of microcapsules during a month long culture in vitro. The section graph of APA microcapsule represents the accurate measurement of layer thickness of APA-Ca with diameter 900 ± 100 and 500 ± 100 μm at 6.01 ± 1.02 and 9.54 ± 2.42 μm (p microcapsules. The microcapsule was stable during the culture for 30 days in vitro. Field emission scanning electron microscopy with freeze drying method was used to detect the surface and thickness of dried microcapsules. From the results, the outer surface of APA-Ca and APA-Ba membrane were smooth and dense, the film thickness of the APA-Ca was about 450-690 nm, while the APA-Ba was approximately 335 nm. In vivo experiment, little significant difference was seen in the change of film thickness of microcapsules in intrapertioneal site for 30 days after transplantation (p > 0.05), except that the recovery of APA-Ba was higher than the APA-Ca microcapsules. The paper showed an easy method to prepare APA-Ca and APA-Ba, and examine their thickness and surface, which could be utilized to study other types of microcapsules.

  7. The roles of proximal and distal muscles in anticipatory postural adjustments under asymmetrical perturbations and during standing on rollerskates.

    Science.gov (United States)

    Shiratori, T; Latash, M

    2000-04-01

    The study addresses two controversial issues surrounding the nature of anticipatory postural adjustments (APAs). The first deals with the reproducible APA patterns in proximal postural muscles and variable APA patterns reported for the muscles controlling the ankle joint (TA-SOL). We hypothesized that the TA-SOL muscles participate mainly in the compensation of lateral and rotational perturbations, in particular those associated with asymmetrical movements. The second issue deals with decreased APAs reported during both very stable and unstable standing. We hypothesized that APA changes during unstable standing might depend on the actual mechanical nature of instability. Eight healthy subjects were recruited who had had no prior experience with rollerskates. They performed series of bilateral and unilateral, flexion and extension movements during regular standing and bilateral movements during standing on rollerskates. EMG changes and shifts of the center of pressure were analyzed within a time window typical of APAs. We found that APAs in proximal muscles were decreased during unilateral shoulder movements as compared to APAs during bilateral movements but did not show right-left differences. In contrast, the distal muscles (TA-SOL) showed little involvement during bilateral movements, while a clear right-left asymmetry was seen during unilateral movements. Bilateral movements performed while standing on rollerskates were accompanied by unchanged APAs in the proximal muscle pairs and increased APAs in the TA-SOL pair. We conclude that the proximal muscles provide a general pattern counteracting expected perturbations in the anterior-posterior direction while the distal muscles deal with asymmetrical perturbations and the modulation of APAs in unusual conditions such as standing on rollerskates. There seems to be no unambiguous relation between the magnitude of APAs and the stability of standing: Depending on the exact mechanical nature of postural instability, it

  8. Degradation Kinetics and Mechanism of a β-Lactam Antibiotic Intermediate, 6-Aminopenicillanic Acid, in a New Integrated Production Process.

    Science.gov (United States)

    Su, Min; Sun, Hua; Zhao, Yingying; Lu, Aidang; Cao, Xiaohui; Wang, Jingkang

    2016-01-01

    In an effort to promote sustainability and to reduce manufacturing costs, the traditional production process for 6-aminopenicillanic acid (6-APA) has been modified to include less processing units. The objectives of this study are to investigate the degradation kinetics of 6-APA, to propose a reasonable degradation mechanism, and to optimize the manufacturing conditions within this new process. A series of degradation kinetic studies were conducted in the presence of impurities, as well as at various chemical and physical conditions. The concentrations of 6-APA were determined by high-performance liquid chromatography. An Arrhenius-type kinetic model was established to give a more accurate prediction on the degradation rates of 6-APA. A hydrolysis degradation mechanism is shown to be the major pathway for 6-APA. The degradation mechanisms and the kinetic models for 6-APA in the new system enable the design of a good manufacturing process with optimized parameters. Copyright © 2016. Published by Elsevier Inc.

  9. 77 FR 36170 - TSCA Inventory Update Reporting Modifications; Chemical Data Reporting; 2012 Submission Period...

    Science.gov (United States)

    2012-06-18

    ... U.S.C. 2607(a). Under section 553(b)(3)(B) of the Administrative Procedure Act (APA), 5 U.S.C. 553(b..., under APA section 553(d), 5 U.S.C. 553(d), the Agency may make a rule immediately effective ``for good.... The RFA applies only to rules subject to notice and comment rulemaking requirements under the APA, 5 U...

  10. The Role of Proprioception in the Sagittal Setting of Anticipatory Postural Adjustments During Gait Initiation

    OpenAIRE

    Pereira Marcelo P.; Pelicioni Paulo H. Silva; Gobbi Lilian T.B.

    2015-01-01

    Purpose. Previous studies have studied the role of proprioception on the setting of anticipatory postural adjustments (APA) during gait initiation. However, these studies did not investigate the role of proprioception in the sagittal APA setting. We aimed to investigate the role of proprioception manipulation to induce APA sagittal adaptations on gait initiation. Methods. Fourteen healthy adults performed gait initiation without, and with, vibration applied before movement onset, and during m...

  11. Asymmetry of Anticipatory Postural Adjustment During Gait Initiation

    OpenAIRE

    Hiraoka, Koichi; Hatanaka, Ryota; Nikaido, Yasutaka; Jono, Yasutomo; Nomura, Yoshifumi; Tani, Keisuke; Chujo, Yuta

    2014-01-01

    The purpose of this study was to investigate the asymmetry of anticipatory postural adjustment (APA) during gait initiation and to determine whether the process of choosing the initial swing leg affects APA during gait initiation. The participants initiated gait with the leg indicated by a start tone or initiated gait with the leg spontaneously chosen. The dependent variables of APA were not significantly different among the condition of initiating gait with the preferred leg indicated by the...

  12. Report from the American Psychological Association.

    Science.gov (United States)

    Goodstein, L D

    1989-01-01

    This article focuses on some of the difficult circumstances that the American Psychological Association (APA) and the mental health community are facing during the 1980s. While a great deal has been learned about mental health issues of older persons and research has demonstrated that they can benefit by appropriate services, the majority of elders needing mental health services are still not receiving them. Service, research and policy issues of concern to APA are discussed and several positive APA activities are noted.

  13. Antiphospholipid antibodies among pregnant women with recurrent fetal wastage in a tertiary hospital in Northern Nigeria

    OpenAIRE

    Abdullahi, Zubaida Garba; Abdul, Mohammmed A.; Aminu, Sirajo M.; Musa, Bolanle O. P.; Amadu, Lawal; Jibril, El-Bashir M.

    2016-01-01

    Context: The association between antiphospholipid antibodies (APAs) and pregnancy loss has been established and now considered as a treatable cause of pregnancy loss. Data on the prevalence of APA in patients with recurrent pregnancy loss are scarce in our environment. Aims: To determine the prevalence of APA in pregnant women with and without recurrent fetal wastage. Settings and Design: Antenatal clinic of Ahmadu Bello University Teaching Hospital, Zaria, Nigeria. A cross-section analytical...

  14. Amoebapore is an important virulence factor of Entamoeba histolytica

    Indian Academy of Sciences (India)

    We have previously demonstrated that inhibition of expression of amoebapore A (AP-A) by antisense RNA caused a marked decrease in the virulence of the parasite. A four-fold over-expression of AP-A was obtained with plasmid (pA7) which has the ap-a gene under the control of gene EhgLE-3-RP-L21. The virulence of ...

  15. Subcellular RNA profiling links splicing and nuclear DICER1 to alternative cleavage and polyadenylation.

    Science.gov (United States)

    Neve, Jonathan; Burger, Kaspar; Li, Wencheng; Hoque, Mainul; Patel, Radhika; Tian, Bin; Gullerova, Monika; Furger, Andre

    2016-01-01

    Alternative cleavage and polyadenylation (APA) plays a crucial role in the regulation of gene expression across eukaryotes. Although APA is extensively studied, its regulation within cellular compartments and its physiological impact remains largely enigmatic. Here, we used a rigorous subcellular fractionation approach to compare APA profiles of cytoplasmic and nuclear RNA fractions from human cell lines. This approach allowed us to extract APA isoforms that are subjected to differential regulation and provided us with a platform to interrogate the molecular regulatory pathways that shape APA profiles in different subcellular locations. Here, we show that APA isoforms with shorter 3' UTRs tend to be overrepresented in the cytoplasm and appear to be cell-type-specific events. Nuclear retention of longer APA isoforms occurs and is partly a result of incomplete splicing contributing to the observed cytoplasmic bias of transcripts with shorter 3' UTRs. We demonstrate that the endoribonuclease III, DICER1, contributes to the establishment of subcellular APA profiles not only by expected cytoplasmic miRNA-mediated destabilization of APA mRNA isoforms, but also by affecting polyadenylation site choice. © 2016 Neve et al.; Published by Cold Spring Harbor Laboratory Press.

  16. Biaxial and antiferroelectric structure of the orthogonal smectic phase of a bent-shaped molecule and helical structure in a chiral mixture system

    Science.gov (United States)

    Kang, Sungmin; Nguyen, Ha; Nakajima, Shunpei; Tokita, Masatoshi; Watanabe, Junji

    2013-05-01

    We examined the biaxial and antiferroelectric properties in the Smectic-APA (Sm-APA) phase of bent-shaped DC-S-8. The biaxiality, which results from the existence of a secondary director, was well established from birefringence observations in the homeotropically aligned Sm-APA. By entering into Sm-APA phase, the birefringence (Δn, difference between two refractive indices of short axes) continuously increased from 0 to 0.02 with decreasing temperature. The antiferroelectric switching and second harmonic generation (SHG) activity on the field-on state were also observed in the Sm-APA phase, and the evaluated spontaneous polarization (PS) value strongly depended on temperature. The temperature dependence of Δn and PS resembles each other and follows Haller's approximation, showing that the biaxiality is due to polar packing in which the molecules are preferentially packed with their bent direction arranged in the same direction, and that the phase transition of Sm-APA to Sm-A is second order. The biaxiality was further examined in chiral Sm-APA*. Doping with chiral components induced the helical twisting of the secondary director in the Sm-APA* phase, which was confirmed by observing the reflection of the circular dichroism (CD) bands in the homeotropically aligned cell. The helical pitch of Sm-APA* is tunable in the range of 300-700 nm wavelength with a variation in the chiral content of 5 to 10 weight (wt)%.

  17. Low complexity adaptive equalizers for underwater acoustic communications

    Science.gov (United States)

    Soflaei, Masoumeh; Azmi, Paeiz

    2014-08-01

    Interference signals due to scattering from surface and reflecting from bottom is one of the most important problems of reliable communications in shallow water channels. To solve this problem, one of the best suggested ways is to use adaptive equalizers. Convergence rate and misadjustment error in adaptive algorithms play important roles in adaptive equalizer performance. In this paper, affine projection algorithm (APA), selective regressor APA(SR-APA), family of selective partial update (SPU) algorithms, family of set-membership (SM) algorithms and selective partial update selective regressor APA (SPU-SR-APA) are compared with conventional algorithms such as the least mean square (LMS) in underwater acoustic communications. We apply experimental data from the Strait of Hormuz for demonstrating the efficiency of the proposed methods over shallow water channel. We observe that the values of the steady-state mean square error (MSE) of SR-APA, SPU-APA, SPU-normalized least mean square (SPU-NLMS), SPU-SR-APA, SM-APA and SM-NLMS algorithms decrease in comparison with the LMS algorithm. Also these algorithms have better convergence rates than LMS type algorithm.

  18. Theory of affine projection algorithms for adaptive filtering

    CERN Document Server

    Ozeki, Kazuhiko

    2016-01-01

    This book focuses on theoretical aspects of the affine projection algorithm (APA) for adaptive filtering. The APA is a natural generalization of the classical, normalized least-mean-squares (NLMS) algorithm. The book first explains how the APA evolved from the NLMS algorithm, where an affine projection view is emphasized. By looking at those adaptation algorithms from such a geometrical point of view, we can find many of the important properties of the APA, e.g., the improvement of the convergence rate over the NLMS algorithm especially for correlated input signals. After the birth of the APA in the mid-1980s, similar algorithms were put forward by other researchers independently from different perspectives. This book shows that they are variants of the APA, forming a family of APAs. Then it surveys research on the convergence behavior of the APA, where statistical analyses play important roles. It also reviews developments of techniques to reduce the computational complexity of the APA, which are important f...

  19. Simple method for preparation of secondary amides of phosphorylacetic acids and their use for actinide extraction and sorption from nitric acid solutions

    International Nuclear Information System (INIS)

    Artyushin, O.I.; Sharova, E.V.; Odinets, I.L.; Lenevich, S.V.; Mastruykova, T.A.; Morgalyuk, V.P.; Tananaev, I.G.; Pribylova, G.V.; Myasoedova, G.V.; Myasoedov, B.F.

    2004-01-01

    An effective method of synthesis of secondary alkylamides of phosphorylacetic acids (APA), based on amidation of ethyl esters of phosphorylacetic acids with primary aliphatic amines, was developed. Extraction of americium(III) complexes with APA solutions in dichloroethane and uranium(VI) sorption by sorbents with non-covalently fixed APA from nitric acid solutions were studied. In the course of americium(III) extraction there is no correlation between Am III distribution factor and APA structure, whereas during uranium(VI) sorption a dependence of U VI extraction degree on the complexing agent structure is observed [ru

  20. What Is Psychiatry?

    Medline Plus

    Full Text Available ... diagnoses are based on criteria established in APA's Diagnostic and Statistical Manual of Mental Disorders ( DSM-5 ), which contains descriptions, symptoms and other criteria for ...

  1. What Is Psychiatry?

    Medline Plus

    Full Text Available ... Values, and Goals Meet Our Organization Read APA Organization Documents and Policies Work at ... Competency Awards & Leadership Opportunities Advocacy & APAPAC Meetings Search ...

  2. 2012 Annual report of the American Psychological Association.

    Science.gov (United States)

    2013-01-01

    Provides the 2012 Annual Report of the American Psychological Association. In 2012, APA celebrated its 120th anniversary. It has grown from its original 31 members to the largest association of psychologists in the United States and a worldwide leader within the discipline. This edition of the report introduces each directorate and office within APA and talks about their goals and objectives. the president of APA, Dr. Norman Anderson, also gives a brief report which updates you on the activities of the association during its 120th anniversary as the professional home for psychologists and an advocate for the discipline. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  3. Collusion, torture, and inequality: Understanding the actions of the American Psychological Association as institutional betrayal.

    Science.gov (United States)

    Gómez, Jennifer M; Smith, Carly P; Gobin, Robyn L; Tang, Shin Shin; Freyd, Jennifer J

    2016-01-01

    The Hoffman Report (Hoffman et al., 2015) documented devastating information about the American Psychological Association (APA) and the profession of psychology in the United States, prompting a public apology and a formal commitment by APA to correct its mistakes (APA, 2015). In the current article, we utilize betrayal trauma theory (Freyd, 1997), including betrayal blindness (e.g., Freyd, 1996; Tang, 2015) and institutional betrayal (Smith & Freyd, 2014b), to understand and learn from APA's behaviors. We further situate this discussion in the context of inequality, both within APA and in American society generally. We detail how the impact of APA's institutional betrayals extended beyond the organization, its members, and the psychology profession, highlighting the potential for disproportionate harm to minorities, including those who were tortured; Muslims, Middle Easterners, Afghans, and non-Americans who were not tortured; and other minority individuals (Gómez, 2015d). Acknowledging, understanding, and addressing its institutional betrayals offers APA the opportunity to take meaningful corrective and preventive measures. We propose several institutional reparations, including making concrete changes with transparency and conducting self-assessments to inform further needed changes (Freyd & Birrell, 2013). By engaging in institutional courage, APA has the potential to grow into an ethical governing body that fulfills its mission to "advance the creation, communication and application of psychological knowledge to benefit society and improve people's lives" (APA, 2016).

  4. Conned by Conn’s Syndrome

    Directory of Open Access Journals (Sweden)

    F Ismail

    2008-03-01

    Full Text Available Conn’s Syndrome is a rare entity amongst hypertensive patients and imaging of the aldosterone producing adenoma (APA can prove challenging but is none the less very important for surgical planning and cure. We present two patients with MRI confirmation of APA with negative and equivocal computed tomography (CT scans.

  5. Teen Dating Violence Prevention Program Assessment

    Science.gov (United States)

    Lucas, Quincy Arrianna Rose

    2013-01-01

    The American Psychological Association (APA) has identified the prevention of and intervention in relationship violence as a top priority (APA, n.d.). According to the Center for Disease Control and Prevention's 2012 Teen Dating Violence Fact Sheet, dating violence is a serious problem in the United States. In accordance with Foshee et al. (1998):…

  6. Animated Pedagogical Agents Effects on Enhancing Student Motivation and Learning in a Science Inquiry Learning Environment

    Science.gov (United States)

    van der Meij, Hans; van der Meij, Jan; Harmsen, Ruth

    2015-01-01

    This study focuses on the design and testing of a motivational animated pedagogical agent (APA) in an inquiry learning environment on kinematics. The aim of including the APA was to enhance students' perceptions of task relevance and self-efficacy. Given the under-representation of girls in science classrooms, special attention was given to…

  7. Internship Training Directors' Perceptions of School Psychology Internship Applicants

    Science.gov (United States)

    Mahoney, Emery B.; Perfect, Michelle M.; Edwinson, Roxanne M.

    2015-01-01

    Since the mid-1990s, an imbalance between the number of available American Psychological Association (APA)-accredited internships and applicants has existed. In 2014, 14% of predoctoral psychology students who applied for internships accredited by the APA or members of the Association of Psychology Postdoctoral and Internship Centers (APPIC) did…

  8. Exploratory Study of Asian Pacific American Female Leaders in Higher Education

    Science.gov (United States)

    Mella, Hazel Roca

    2012-01-01

    The purpose of this study was to determine if and to what extent the model minority myth prevents "Asian Pacific American" ("APA") women from achieving the president or chancellor position in higher education institutions. This study explored the experiences of APA female leaders who are presidents and chancellors to discover…

  9. Fip1 regulates mRNA alternative polyadenylation to promote stem cell self-renewal

    Science.gov (United States)

    Lackford, Brad; Yao, Chengguo; Charles, Georgette M; Weng, Lingjie; Zheng, Xiaofeng; Choi, Eun-A; Xie, Xiaohui; Wan, Ji; Xing, Yi; Freudenberg, Johannes M; Yang, Pengyi; Jothi, Raja; Hu, Guang; Shi, Yongsheng

    2014-01-01

    mRNA alternative polyadenylation (APA) plays a critical role in post-transcriptional gene control and is highly regulated during development and disease. However, the regulatory mechanisms and functional consequences of APA remain poorly understood. Here, we show that an mRNA 3′ processing factor, Fip1, is essential for embryonic stem cell (ESC) self-renewal and somatic cell reprogramming. Fip1 promotes stem cell maintenance, in part, by activating the ESC-specific APA profiles to ensure the optimal expression of a specific set of genes, including critical self-renewal factors. Fip1 expression and the Fip1-dependent APA program change during ESC differentiation and are restored to an ESC-like state during somatic reprogramming. Mechanistically, we provide evidence that the specificity of Fip1-mediated APA regulation depends on multiple factors, including Fip1-RNA interactions and the distance between APA sites. Together, our data highlight the role for post-transcriptional control in stem cell self-renewal, provide mechanistic insight on APA regulation in development, and establish an important function for APA in cell fate specification. PMID:24596251

  10. Ethics as an Undergraduate Psychology Outcome: When, Where, and How to Teach It

    Science.gov (United States)

    Ruiz, Ana; Warchal, Judith

    2014-01-01

    The American Psychological Association (APA) recently approved a new set of "Guidelines for the undergraduate psychology major, version 2.0" (APA, 2013a) which addressed ethics specifically. Yet the teaching of ethics receives little attention in publications, national and international institutes, and conferences. Few guidelines for…

  11. Regional Maritime University Journal: Submissions

    African Journals Online (AJOL)

    The APA 5th style for all articles except legal articles ─ In-text references and the accompanying reference list must follow the APA 5th format examples in Appendix 1 ─ Footnotes in this style may only be used for explanatory notes or for the provision of substantive information and never for referencing ─ In the reference ...

  12. CASE REPORT CASE CASE Conned by Conn's syndrome

    African Journals Online (AJOL)

    2008-01-08

    Jan 8, 2008 ... ing of the aldosterone-producing adenoma (APA) can prove challenging but is nonetheless very important for surgical planning and cure. We present two patients with MRI (magnetic resonance imaging) confirma- tion of APA with negative and equivocal CT (computed tomography) scans. Case 1.

  13. 77 FR 6681 - Approval and Promulgation of State Plans for Designated Facilities and Pollutants; State of...

    Science.gov (United States)

    2012-02-09

    ... (APA) which, upon finding ``good cause,'' authorizes agencies to dispense with public participation.... EPA also finds that there is good cause under APA section 553(d)(3) for this correction to become effective on the date of publication of this action. [[Page 6682

  14. Difference, Adapted Physical Activity and Human Development: Potential Contribution of Capabilities Approach

    Science.gov (United States)

    Silva, Carla Filomena; Howe, P. David

    2012-01-01

    This paper is a call to Adapted Physical Activity (APA) professionals to increase the reflexive nature of their practice. Drawing upon Foucault's concept of governmentality (1977) APA action may work against its own publicized goals of empowerment and self-determination. To highlight these inconsistencies, we will draw upon historical and social…

  15. Self-Efficacy and Preparation of Scholarly Writing: Online Doctoral Coursework to Comprehensive Examination--a Mixed Method Study

    Science.gov (United States)

    Thomas, Sonya C.

    2013-01-01

    Writing is seldom explicitly taught, most specifically, in academic and scholarly writing. Therefore, this mixed methods correlational phenomenology research study explored the correlation between self-efficacy perception and course room preparation for the comprehensive examination, APA standards in the course room, APA standards evaluation for…

  16. Microarray Meta-Analysis of RNA-Binding Protein Functions in Alternative Polyadenylation

    Science.gov (United States)

    Hu, Wenchao; Liu, Yuting; Yan, Jun

    2014-01-01

    Alternative polyadenylation (APA) is a post-transcriptional mechanism to generate diverse mRNA transcripts with different 3′UTRs from the same gene. In this study, we systematically searched for the APA events with differential expression in public mouse microarray data. Hundreds of genes with over-represented differential APA events and the corresponding experiments were identified. We further revealed that global APA differential expression occurred prevalently in tissues such as brain comparing to peripheral tissues, and biological processes such as development, differentiation and immune responses. Interestingly, we also observed widespread differential APA events in RNA-binding protein (RBP) genes such as Rbm3, Eif4e2 and Elavl1. Given the fact that RBPs are considered as the main regulators of differential APA expression, we constructed a co-expression network between APAs and RBPs using the microarray data. Further incorporation of CLIP-seq data of selected RBPs showed that Nova2 represses and Mbnl1 promotes the polyadenylation of closest poly(A) sites respectively. Altogether, our study is the first microarray meta-analysis in a mammal on the regulation of APA by RBPs that integrated massive mRNA expression data under a wide-range of biological conditions. Finally, we present our results as a comprehensive resource in an online website for the research community. PMID:24622240

  17. Joint effect of freshwater plume and coastal upwelling on phytoplankton growth off the Changjiang River

    Science.gov (United States)

    Tseng, Y.-F.; Lin, J.; Dai, M.; Kao, S.-J.

    2014-01-01

    The Changjiang (Yangtze) River discharges vast amount of unbalanced nutrients (dissolved inorganic nitrogen and phosphorus with N / P ratio > 80 in general) into the East China Sea in summer. To study nutrient dynamics and P-stress potential for phytoplankton, a cruise was conducted in the Changjiang plume during summer 2011. With 3-D observations of nutrients, chlorophyll a (Chl a), and bulk alkaline phosphatase activity (APA), we concluded that the Changjiang Diluted Water and coastal upwelling significantly influenced the horizontal and vertical heterogeneities of phytoplankton P deficiency in the Changjiang plume. Allochthonous APA was detected at nutrient-enriched freshwater end. Excessive N (~ 10 to 112 μM) was observed throughout the entire plume surface. In the plume fringe featuring stratification and excess N, diapycnal phosphate supply was blocked and phytoplankton APA was stimulated for growth. We observed an upwelling just attaching to the turbidity front at seaward side where Chl a peaked yet much less APA was detected. An external phosphate supply from subsurface, which promoted phytoplankton growth but inhibited APA, was suggested to be sourced from the Nearshore Kuroshio Branch Current. In the so hydrographically complicated Changjiang plume, phosphate supply instead of its concentration may be more important in determining the expression of APA. Meanwhile, allochthonous APA may also alter the usefulness of APA as a P-stress indicator.

  18. Introduction To The Special Section: The American Psychiatric Association's Research Agenda For The DSM-V

    DEFF Research Database (Denmark)

    Widiger, Thomas A; Simonsen, Erik

    2005-01-01

    of the American Psychiatric Association's (APA) Diagnostic and Statistical Manual of Mental Disorders. This article provides the historical background for and a brief description of the first conference, which was concerned with the research that would help move the field toward a dimensional classification...... of personality disorder. (PsycINFO Database Record (c) 2008 APA, all rights reserved) (from the journal abstract)...

  19. Developing a Taxonomy of Helpful and Harmful Practices for Clinical Work with Boys and Men

    Science.gov (United States)

    Mahalik, James R.; Good, Glenn E.; Tager, David; Levant, Ronald F.; Mackowiak, Christopher

    2012-01-01

    This study drew upon the knowledge base of member practitioners of the American Psychological Association (APA) to develop a taxonomy of helpful and harmful practices for treatment with boys and men. Four hundred seventy-five APA-member practitioners solicited from practice-related divisions provided responses to 4 open-ended questions about…

  20. ORIGINAL ARTICLES

    African Journals Online (AJOL)

    In 1991 the American Psychological. Association (APA) appointed a task force on pharmacology and in 1995 endorsed a policy supporting the RTF for psychologists.' The APA has demonstrated considerable interest in this issue as it has emerged in South Africa, and has offered ongoing support to PsySSA in this regard.

  1. Cloning and over-expression of Penicillin G acylase in Escherichia ...

    African Journals Online (AJOL)

    STORAGESEVER

    2010-05-03

    May 3, 2010 ... Penicillin G acylase (PGA) is a type II penicillin acylase that hydrolyzes Penicillin G to 6-aminopenicillanic acid (6-. APA) and phenyl acetic acid (PAA) (Ohashi et al., 1989;. Zietkiewicz et al., 1994). 6-APA is starting material for production of semi-synthetic penicillins (Kumar et al.,. 2007; Ochman et al., 1988) ...

  2. First rank symptoms: concepts and diagnostic utility

    African Journals Online (AJOL)

    Diagnostic and Statistical Manual of Mental Disorders. 4th edition, text revision: Washington DC, APA,. 2000. 13. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 3rd edition revision: Washington DC, APA,. 1987. 14. American Psychiatric Association. Diagnostic and Statistical Manual.

  3. Pedophilia and the Culture Wars.

    Science.gov (United States)

    Zuriff, G. E.

    2000-01-01

    Discusses reaction to research findings published in a journal of the American Psychological Association (APA) which concluded that classifying sexual behavior between adults and children as abuse merely because it is considered illegal or immoral, even in the absence of harm, is not scientifically valid. Notes the APA's stand on the study's…

  4. 78 FR 57066 - Final Waivers and Extensions of Project Periods; American Indian Vocational Rehabilitation...

    Science.gov (United States)

    2013-09-17

    ... Effective Date The Administrative Procedure Act (APA) requires that a substantive rule must be published at... entities with the delay. Therefore, the Secretary waives the APA's delayed effective date provision for... Format: Individuals with disabilities can obtain this document in an accessible format (e.g., braille...

  5. 78 FR 11984 - Approval and Promulgation of Implementation Plans; State of Hawaii; Update to Materials...

    Science.gov (United States)

    2013-02-21

    ... revised SIP document, IBR procedures and ``Identification of plan'' format are discussed in further detail... Act (APA) which, upon finding ``good cause,'' authorizes agencies to dispense with public... avoiding the 30-day delayed effective date otherwise provided for in the APA). Today's rule simply codifies...

  6. 75 FR 41836 - Waiver and Extension of Project Period

    Science.gov (United States)

    2010-07-19

    .... Individuals with disabilities can obtain this document in an accessible format (e.g., braille, large print... any purpose. Waiver of Rulemaking Under the Administrative Procedure Act (5 U.S.C. 553) (APA) the... requirements of the APA for this waiver because it would be impracticable and contrary to the public interest...

  7. 78 FR 44884 - Approval and Promulgation of Air Quality Implementation Plans; West Virginia; Update to Materials...

    Science.gov (United States)

    2013-07-25

    ... document, IBR procedures and ``Identification of plan'' format are discussed in further detail in the May...)(3)(B) of the Administrative Procedures Act (APA) which, upon finding ``good cause,'' authorizes... effective immediately (thereby avoiding the 30-day delayed effective date otherwise provided for in the APA...

  8. 78 FR 46516 - Approval and Promulgation of Air Quality Implementation Plans; Pennsylvania; Update to Materials...

    Science.gov (United States)

    2013-08-01

    ... document, IBR procedures and ``Identification of plan'' format are discussed in further detail in the May... under the ``good cause'' exemption in section 553(b)(3)(B) of the Administrative Procedures Act (APA... delayed effective date otherwise provided for in the APA). Today's rule simply codifies provisions which...

  9. 77 FR 24408 - Modification of Significant New Uses of Tris Carbamoyl Triazine; Technical Amendment

    Science.gov (United States)

    2012-04-24

    ... text in that document did not satisfy OFR's format requirements, and a second correction was necessary... Administrative Procedure Act (APA), 5 U.S.C. 553(b)(3)(B), provides that, when an Agency for good cause finds... the APA or any other statute (see Unit III. of this document), it is not subject to the regulatory...

  10. 78 FR 54762 - List of Fair Employment Practice Agencies

    Science.gov (United States)

    2013-09-06

    ...). Copies of this final rule are available in the following alternative format: large print, Braille, electronic computer disk, and audio-tape. Requests for this notice in an alternative format should be made to... Procedures The Administrative Procedures Act (APA) The Administrative Procedure Act (APA) provides an...

  11. Animated pedagogical agents effects on enhancing student motivation and learning in a science inquiry learning environment

    NARCIS (Netherlands)

    van der Meij, Hans; van der Meij, Jan; Harmsen, Ruth

    This study focuses on the design and testing of a motivational animated pedagogical agent (APA) in an inquiry learning environment on kinematics. The aim of including the APA was to enhance students’ perceptions of task relevance and selfefficacy. Given the under-representation of girls in science

  12. Animated pedagogical agents effects on enhancing student motivation and learning in a science inquiry learning environment

    NARCIS (Netherlands)

    van der Meij, Hans; van der Meij, Jan; Harmsen, Ruth

    2015-01-01

    This study focuses on the design and testing of a motivational animated pedagogical agent (APA) in an inquiry learning environment on kinematics. The aim of including the APA was to enhance students’ perceptions of task relevance and self-efficacy. Given the under-representation of girls in science

  13. 76 FR 71604 - Kamal Tiwari, M.D.; Pain Management and Surgery Center of Southern Indiana; Decision and Order

    Science.gov (United States)

    2011-11-18

    ...\\ Under the Administrative Procedure Act (APA), an agency ``may take official notice of facts at any stage in a proceeding- even in the final decision.'' U.S. Dept. of Justice, Attorney General's Manual on... with the APA and DEA's regulations, Respondent is ``entitled on timely request, to an opportunity to...

  14. 75 FR 16088 - Notice: Request for Substantive Comments on the EAC's Proposed Requirements for the Testing of...

    Science.gov (United States)

    2010-03-31

    .... (7) Technical Data Package. (8) Systems Users Manual. DATES: Comments must be received on or before 4..., adjudicative, or licensing provisions of the Administrative Procedures Act (APA). It is a voluntary effort by... intended to make any of the APA's rulemaking provisions applicable to development of this or future EAC...

  15. 77 FR 71083 - Regulations Affecting Credit Unions; Technical Amendments

    Science.gov (United States)

    2012-11-29

    ...) of Appendix A to part 749 states that credit unions should permanently retain all current manuals.... III. Regulatory Procedures Final Rule Generally, the Administrative Procedure Act (APA) requires a... statutorily required by the Dodd-Frank Act. The APA permits an agency to forego the notice and comment period...

  16. 76 FR 18365 - Fair Credit Reporting Act and Bank Secrecy Act Compliance

    Science.gov (United States)

    2011-04-04

    ... Procedure Act (APA), an agency may, for good cause, find (and incorporate the finding and a brief statement... and comment procedures prescribed by the APA are unnecessary because the final rule makes technical... Asked Questions, and the FFIEC Bank Secrecy Act/Anti-Money Laundering Examination Manual. (iii...

  17. Tobacco industry influence on the definition of tobacco related disorders by the American Psychiatric Association

    OpenAIRE

    Neuman, M; Bitton, A; Glantz, S

    2005-01-01

    Objective: The Diagnostic and statistical manual of mental disorders, third edition (DSM-III), published by the American Psychiatric Association (APA) in 1980, included the first official definitions by the APA of tobacco dependence and tobacco withdrawal. Tobacco industry efforts to influence the DSM-III were investigated.

  18. 44 CFR 1.1 - Purpose.

    Science.gov (United States)

    2010-10-01

    ... and procedures incorporate those provisions of section 4 of the Administrative Procedure Act (APA) (5 U.S.C. 553) which FEMA will follow. This part and internal FEMA Manuals implement Executive Order 12291. (b) Rules which must be published are described in section 3(a) of the APA, 5 U.S.C. 552(a). FEMA...

  19. 76 FR 55788 - Amendments To Include New Applicant Types on Form ID

    Science.gov (United States)

    2011-09-09

    ...\\ See EDGAR Filing Manual (Volume I) General Information (Section 2.4, Accessing EDGAR). Currently, Form... Administrative Procedure Act (``APA'') \\34\\ generally requires an agency to publish, before adopting a rule....'' \\36\\ Further, the APA also generally requires that an agency publish a rule in the Federal Register 30...

  20. 78 FR 79600 - Removal of Person From the Entity List Based on a Removal Request

    Science.gov (United States)

    2013-12-31

    ... for a manual or electronic submission. Total burden hours associated with the PRA and OMB control... (APA), 5 U.S.C. 553(b)(3)(B), BIS finds good cause to waive requirements that this rule be subject to... assessing such removal requests. Section 553(d) of the APA generally provides that rules may not take effect...

  1. 77 FR 60047 - Adjustment of Civil Monetary Penalties for Inflation

    Science.gov (United States)

    2012-10-02

    ... Delayed Effective Date Under the Administrative Procedure Act (APA) (5 U.S.C. 553), the Department generally offers interested parties the opportunity to comment on proposed regulations. However, the APA... of Justice, Attorney General's Manual on the Administrative Procedure Act 31 (1947) and South...

  2. 78 FR 54373 - Records of Failed Insured Depository Institutions

    Science.gov (United States)

    2013-09-04

    .../compliance/manual/pdf/II-8.1.pdf . The ``reasonably accessible'' limitation permits the FDIC to forego... instances where the FDIC issues a final rule as defined by the APA (5 U.S.C. 551 et seq.). Because the FDIC is issuing a final rule as defined by the APA, the FDIC will file the reports required by the SBREFA...

  3. 78 FR 21230 - Airworthiness Directives; Airbus Airplanes

    Science.gov (United States)

    2013-04-10

    ... Procedure Act (APA) (Pub. L. 79- 404, 5 U.S.C. 551, et.seq.) we are required to provide notice of our intent... participate in rulemaking actions unless we find good cause to bypass those requirements. (The APA is a body... Airbus A318/ A319/A320 Aircraft Maintenance Manual. Request To Correct Typographical Error Virgin America...

  4. 77 FR 35054 - Donald Brooks Reece II, M.D.; Dismissal of Proceeding

    Science.gov (United States)

    2012-06-12

    ... the Administrative Procedure Act (APA), an agency ``may take official notice of facts at any stage in a proceeding-even in the final decision.'' U.S. Dept. of Justice, Attorney General's Manual on the Administrative Procedure Act 80 (1947) (Wm. W. Gaunt & Sons, Inc., Reprint 1979). In accordance with the APA and...

  5. 77 FR 29696 - James Edgar Lundeen, Sr., M.D.; Dismissal of Proceeding

    Science.gov (United States)

    2012-05-18

    .... \\2\\ In accordance with the Administrative Procedure Act (APA), an agency ``may take official notice... General's Manual on the Administrative Procedure Act 80 (1947) (Wm. W. Gaunt & Sons, Inc., Reprint 1979). In accordance with the APA and DEA's regulations, Respondent is ``entitled on timely request to an...

  6. Design and Validation of a Rubric to Assess the Use of American Psychological Association Style in Scientific Articles

    Science.gov (United States)

    Merma Molina, Gladys; Peña Alfaro, Hilda; Peña Alfaro González, Silvia Rosa

    2017-01-01

    In this study, the researchers will explore the process of designing and validating a rubric to evaluate the adaptation of scientific articles in the format of the "American Psychological Association" (APA). The rubric will evaluate certain aspects of the APA format that allow authors, editors, and evaluators to decide if the scientific…

  7. 75 FR 33501 - Definitions for Regulations Affecting All Savings Associations; Money Market Deposit Accounts

    Science.gov (United States)

    2010-06-14

    ... notice and comment is unnecessary under the Administrative Procedure Act (APA) and is implementing this... would be at a competitive disadvantage. \\3\\ 74 FR 47050 (September 15, 2009). C. Amendment to Definition... for dispensing with the 30-day delay required by the Administrative Procedure Act (APA). OTS...

  8. Anticipatory postural adjustment patterns during gait initiation across the adult lifespan.

    Science.gov (United States)

    Lu, Chiahao; Amundsen Huffmaster, Sommer L; Harvey, Jack C; MacKinnon, Colum D

    2017-09-01

    Gait initiation involves a complex sequence of anticipatory postural adjustments (APAs) during the transition from steady state standing to forward locomotion. APAs have four core components that function to accelerate the center of mass forwards and towards the initial single-support stance limb. These components include loading of the initial step leg, unloading of the initial stance leg, and excursion of the center of pressure in the posterior and lateral (towards the stepping leg) directions. This study examined the incidence, magnitude, and timing of these components and how they change across the lifespan (ages 20-79). 157 individuals performed five trials of self-paced, non-cued gait initiation on an instrumented walkway. At least one component of the APA was absent in 24% of all trials. The component most commonly absent was loading of the initial step leg (absent in 10% of all trials in isolation, absent in 10% of trials in conjunction with another missing component). Trials missing all four components were rare (1%) and were observed in both younger and older adults. There was no significant difference across decades in the incidence of trials without an APA, the number or type of APA components absent, or the magnitude or timing of the APA components. These data demonstrate that one or more components of the APA sequence are commonly absent in the general population and the spatiotemporal profile of the APA does not markedly change with ageing. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. Role of Nitric Oxide in MPTP-Induced Dopaminergic Neuron Degeneration

    Science.gov (United States)

    2006-06-01

    deliner an ApaS Inhillhtoc this 88. fleaunee, A. G. Hat lMoter neurons in Cu,/7n superoxide 3, 130t-1306 (2000). paper shows the Instrumnental rateof...dehydrogenase, Norma Romero for that DPHB-derived NADH, by feeding complex I, increas- her assistance in animal care, and Soliman Bakr for his es the

  10. 2005 Annual Report of the American Psychological Association

    Science.gov (United States)

    American Psychologist, 2006

    2006-01-01

    This annual report of the American Psychological Association (APA) describes the association's activities and accomplishments in 2005. The examples provided in this report are a small sampling of all that APA is doing to advance the discipline of psychology in an ever-changing world.

  11. Immuno-Hematological Abnormalities Associated with Antiphospholipid Antibodies in Pregnancy (2. Abnormalities in the Immune Responses between Mother and Fetus)

    OpenAIRE

    杉, 俊隆; Toshitaka, SUGI; 東海大学医学部産婦人科学教室; Department of Obstetrics and Gynecology, Tokai University School of Medicine

    1999-01-01

    Antiphospholipid antibodies (aPA) to anionic phospholipids such as cardiolipin and phosphatidylserine have been described in patients with thrombosis, thrombocytopenia and recurrent fetal loss. Autoantibodies reactive to zwitterionic phospholipids such as phosphatidylethanolamine (PE) have not been studied extensively. Most lupus anticoagulatnt and aPA literature is limited to descriptions of anionic phospholipids such as cardiolipin, however, antiphosphatidylethanolamine antibodies (aPE ) al...

  12. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    In multiple logistic regression analysis, BsmI and ApaI SNPs of VDR genes were significantly associated with overweight and obesity. The UCP2–VDR ApaI interaction to susceptibility of overweight and obesity was first observed from logistic regression analysis, and then confirmed in the multifactor dimensionality reduction ...

  13. Reporting and Interpreting Effect Size in Quantitative Agricultural Education Research

    Science.gov (United States)

    Kotrlik, Joe W.; Williams, Heather A.; Jabor, M. Khata

    2011-01-01

    The Journal of Agricultural Education (JAE) requires authors to follow the guidelines stated in the Publication Manual of the American Psychological Association [APA] (2009) in preparing research manuscripts, and to utilize accepted research and statistical methods in conducting quantitative research studies. The APA recommends the reporting of…

  14. An Introductory Summary of Various Effect Size Choices.

    Science.gov (United States)

    Cromwell, Susan

    This paper provides a tutorial summary of some of the many effect size choices so that members of the Southwest Educational Research Association would be better able to follow the recommendations of the American Psychological Association (APA) publication manual, the APA Task Force on Statistical Inference, and the publication requirements of some…

  15. Yeki Bood/Yeki Na Bood: Writing and Publishing as a Teacher Researcher.

    Science.gov (United States)

    Fecho, Bob

    2003-01-01

    Discusses considerations faced by practitioner researchers as they write for publication, particularly as they encounter the template of the Publication Manual of the American Psychological Association (APA). Argues that some APA conventions--such as beginning an article with theory rather than the story of the research--do not suite the purposes…

  16. An Introduction to Confidence Intervals for Both Statistical Estimates and Effect Sizes.

    Science.gov (United States)

    Capraro, Mary Margaret

    This paper summarizes methods of estimating confidence intervals, including classical intervals and intervals for effect sizes. The recent American Psychological Association (APA) Task Force on Statistical Inference report suggested that confidence intervals should always be reported, and the fifth edition of the APA "Publication Manual"…

  17. Interpreting and Reporting Effect Sizes in Research Investigations.

    Science.gov (United States)

    Tapia, Martha; Marsh, George E., II

    Since 1994, the American Psychological Association (APA) has advocated the inclusion of effect size indices in reporting research to elucidate the statistical significance of studies based on sample size. In 2001, the fifth edition of the APA "Publication Manual" stressed the importance of including an index of effect size to clarify…

  18. Statistical Methods in Psychology Journals.

    Science.gov (United States)

    Willkinson, Leland

    1999-01-01

    Proposes guidelines for revising the American Psychological Association (APA) publication manual or other APA materials to clarify the application of statistics in research reports. The guidelines are intended to induce authors and editors to recognize the thoughtless application of statistical methods. Contains 54 references. (SLD)

  19. Adsorption of human immunoglobulin to implantable alginate-poly-L-lysine microcapsules : Effect of microcapsule composition

    NARCIS (Netherlands)

    Tam, Susan K.; de Haan, Bart J.; Faas, Marijke M.; Halle, Jean-Pierre; Yahia, L'Hocine; de Vos, Paul

    2009-01-01

    Alginate-poly-L-lysine-alginate (APA) microcapsules continue to be the most widely Studied device for the immuno-protection of transplanted therapeutic cells. Producing APA microcapsules having a reproducible and high level of biocompatibility requires an understanding of the mechanisms of the

  20. Multicultural Training of Clinical and Counseling Psychology Doctoral Students: Ideals vs. Practice

    Science.gov (United States)

    White, Bryana F. C.

    2013-01-01

    The American Psychological Association (APA), which is the advocating body for the field of psychology, emphasizes the importance of multicultural competencies for researchers and clinicians (APA, 2003; 2010). Graduate students are the field's future professionals. The multicultural training of doctoral level clinical and counseling…

  1. An Examination of Current Adapted Physical Activity Provision in Primary and Special Schools in Ireland

    Science.gov (United States)

    Crawford, Susan

    2011-01-01

    The Disability in Sport Taskforce report examining adapted physical activity (APA) in the Irish context (Department of Education and Science, 1999) found that teachers involved in primary mainstream and specialist settings expressed a grave lack of self-confidence, due to lack of training, in the delivery of APA programmes to children with special…

  2. Thermoplastic Composite Wind Turbine Blades : Kinetics and Processability

    NARCIS (Netherlands)

    Teuwen, J.J.E.

    2011-01-01

    In previous research, the potential of glass fibre reinforced anionic polyamide-6 (APA-6) composites for use in wind turbine blades was proven. Based on polymer properties, viscosity, processing time, costs and recyclability, APA-6 composites are considered the most suitable reactive thermoplastic

  3. Evaluation of anti-pneumococcal capsular antibodies as adjunctive therapy in experimental pneumococcal meningitis

    DEFF Research Database (Denmark)

    Brandt, Christian; Frimodt-Moller, N; Lundgren, Jens Dilling

    2006-01-01

    serotype 3. All rats received ceftriaxone starting 26 h post-infection. APAS was administered either at the time of infection or 26 h post-infection and effects were compared with rats treated with antibiotics only. RESULTS AND CONCLUSION: A significant clinical benefit was found when APAS was given...

  4. Probability as certainty : Dichotomous thinking and the misuse of p values

    NARCIS (Netherlands)

    Hoekstra, Rink; Finch, Sue; Kiers, Henk A.L.; Johnson, Addie

    2006-01-01

    Significance testing is widely used and often criticized. The Task Force on Statistical Inference of the American Psychological Association (TFSI, APA; Wilkinson & TFSI, 1999) addressed the use of significance testing and made recommendations that were incorporated in the fifth edition of the APA

  5. 688,112 statistical results : Content mining psychology articles for statistical test results

    NARCIS (Netherlands)

    Hartgerink, C.H.J.

    2016-01-01

    In this data deposit, I describe a dataset that is the result of content mining 167,318 published articles for statistical test results reported according to the standards prescribed by the American Psychological Association (APA). Articles published by the APA, Springer, Sage, and Taylor & Francis

  6. Amplexicaule A exerts anti-tumor effects by inducing apoptosis in human breast cancer

    Science.gov (United States)

    Shu, Guangwen; Wan, Dingrong; He, Feng; Loaec, Morgann; Ding, Yali; Li, Jun; Dovat, Sinisa; Yang, Gaungzhong; Song, Chunhua

    2016-01-01

    Chemotherapy is the main treatment for patients with breast cancer metastases, but natural alternatives have been receiving attention for their potential as novel anti-tumor reagents. Amplexicaule A (APA) is a flavonoid glucoside isolated from rhizomes of Polygonum amplexicaule D. Don var. sinense Forb (PADF). We found that APA has anti-tumor effects in a breast cancer xenograft mouse model and induces apoptosis in breast cancer cell lines. APA increased levels of cleaved caspase-3,-8,-9 and PARP, which resulted from suppression of MCL-1 and BCL-2 expression in the cells. APA also inactivated the Akt/mTOR pathway in breast cancer cells. Thus, APA exerts a strong anti-tumor effect on breast cancer cells, most likely through induction of apoptosis. Our study is the first to identify this novel anti-tumor compound and provides a new strategy for isolation and separation of single compounds from herbs. PMID:26943775

  7. Alternative polyadenylation of tumor suppressor genes in small intestinal neuroendocrine tumors

    DEFF Research Database (Denmark)

    Rehfeld, Anders Aagaard; Plass, Mireya; Døssing, Kristina

    2014-01-01

    The tumorigenesis of small intestinal neuroendocrine tumors (SI-NETs) is poorly understood. Recent studies have associated alternative polyadenylation (APA) with proliferation, cell transformation, and cancer. Polyadenylation is the process in which the pre-messenger RNA is cleaved at a polyA site...... and a polyA tail is added. Genes with two or more polyA sites can undergo APA. This produces two or more distinct mRNA isoforms with different 3' untranslated regions. Additionally, APA can also produce mRNAs containing different 3'-terminal coding regions. Therefore, APA alters both the repertoire...... and the expression level of proteins. Here, we used high-throughput sequencing data to map polyA sites and characterize polyadenylation genome-wide in three SI-NETs and a reference sample. In the tumors, 16 genes showed significant changes of APA pattern, which lead to either the 3' truncation of mRNA coding regions...

  8. The Southern Society for Philosophy and Psychology and Francis Cecil Sumner.

    Science.gov (United States)

    Thomas, Roger K

    2011-01-01

    In 1939, a psychologist could become a member of the Southern Society for Philosophy and Psychology (SSPP) automatically with the endorsement of two members, payment of dues, and membership in the American Psychological Association (APA). Non-APA members with endorsements and payment of dues had to be voted in by the membership. In 1940, the rules for admission were changed to eliminate the automatic membership for APA members. Francis Cecil Sumner, the first African American PhD in psychology, qualified for SSPP membership as a member of the APA in 1939, but the SSPP's council delayed his membership and introduced the amendment to its constitution that eliminated Sumner's route to membership. This article examines the circumstances surrounding council's actions and the role that Sumner's application for membership played in it as an example of the role that race and discrimination played in the decision to change the route to SSPP membership for members of the APA.

  9. Auricular point acupressure as an adjunct analgesic treatment for cancer patients: a feasibility study.

    Science.gov (United States)

    Yeh, Chao Hsing; Chien, Lung-Chang; Chiang, Yi Chien; Ren, Dianxu; Suen, Lorna Kwai-Ping

    2015-06-01

    This study aimed (1) to examine the feasibility of an auricular point acupressure (APA) research protocol in terms of recruitment and for the assessment and management of pain and (2) to examine the potential APA analgesic effects for cancer patients. This study was a repeated-measures one-group design. Participants were recruited from the cancer center follow-up clinic affiliated with a large university hospital in the northeastern United States. Participants included 50 patients aged 55-87 years with a diagnosis of cancer. Participants received 7 days of APA treatment for their pain. After appropriate acupoints were identified, vaccaria seeds were carefully taped onto each selected auricular point on each ear. The study recruitment and retention rates were 92% and 91%, respectively. Importantly, the study found preliminary evidence for the analgesic effects of APA for cancer pain management. For example, by the end of the 7-day study, APA reduced pain intensity more than 55% for "worst pain" and about 57% for "average pain" and "pain intensity." Moreover, the use of pain medication was reduced during the APA treatment (e.g., 78% of patients [n = 39] took less pain medication than before the treatment). APA appears to be highly acceptable to patients with cancer-related pain. However, without a placebo control, we cannot draw conclusive evidence for the analgesic effect of APA for cancer patients. A sham group must be added to future studies to differentiate the true effects of APA from the possible psychological effects of the APA treatment. Copyright © 2015 American Society for Pain Management Nursing. Published by Elsevier Inc. All rights reserved.

  10. Alkaline Phosphatase Activity : an overlooked player on the phosphate behavior in macrotidal estuaries

    Science.gov (United States)

    Delmas, Daniel; Labry, Claire; Youenou, Agnes; Quere, Julien; Auguet, Jean Christophe; Montanie, Helene

    2014-05-01

    The non-conservative behavior of phosphate within the estuarine salinity gradient is essentially assigned to physico-chemical processes, such as desorption at low salinity and to benthic exchanges. Microbial phosphatase activity (APA), generally related to phosphate deficiency, is seldom studied in phosphate rich estuarine waters. In order to address the impact of microbial activity (bacterial abundance, production BSP, APA) on phosphate behavior, we studied these activities on a seasonal basis within the salinity gradient of two macrotidal estuaries presenting different levels of suspended solids. Whatever the season the Charente estuary is characterized by high levels of Suspended Particulate Matter (SPM > 1g.L-1), particularly in the Maximum Turbidity Zone (MTZ) located at the 5-10 psu. In this area characterized by high BSP and APA there is a significant increase of PO4 levels especially during summer. In the Aulne estuary the particle load is significantly lower (1/10) but high BSP and APA are equally recorded. In the highly turbid waters of the Charente estuary, active phytoplankton is virtually absent as pheopigments constitute up to 80% of the total pigments, particularly in the MTZ, therefore APA may essentially have a bacterial origin. In the Aulne estuary attached bacteria are dominant, both in numbers and production, and their distribution along the haline gradient perfectly follows those of APA and phosphate levels. These observations, associated with the very close relationships observed between APA, SPM and BSP, suggest that APA derive mainly from bacterial (attached) origin and operate at the expense of particulate phosphorus and hence contribute to PO4 regeneration, especially in spring and summer. Finally, as APA increased as PO4, whereas the reverse is observed in both fresh and marine waters, an original scheme for APA regulation, related to the large dominance of attached bacteria can be described for the estuarine waters.

  11. Pelvic magnetic resonance imaging angioanatomy of the arterial blood supply to the penis in suspected prostate cancer patients

    International Nuclear Information System (INIS)

    Thai, Cao Tan; Karam, Ibrahim Michel; Nguyen-Thi, Phi Linh; Lefèvre, Frédéric; Hubert, Jacques; Felblinger, Jacques; Eschwège, Pascal

    2015-01-01

    Highlights: • Three patterns of penile arterial supply (according to the classification of Stéphane Droupy). • Our classification about accessory pudendal artery. • Origin of accessory pudendal artery. - Abstract: Purpose: To describe the internal pudendal artery (IPA) and accessory pudendal artery (APA) detected by magnetic resonance (MR) angiography to help surgeons to find and preserve them during radical prostatectomy (RP). Materials and methods: Constrast-enhanced MR 3.0 T angiography of the pelvis were performed in 111 male patients suspected diagnosis of prostate cancer (PCa), and describe the penile arterial blood supply. Results: There are three patterns of the arterial blood supply to the penis (IPA and/or APA) accounting for 51.4%, 46.8% and 1.8% of cases, respectively. About the accessory pudendal artery (APA): 54/111 (48.6%) patients had APA with five different branching patterns, they were type I (APA bilateral symmetry): 17 (31.5%); type II (APA bilateral asymmetry): 1 (1.9%); type III (APA unilateral lateral): 13 (24%); type IV (APA unilateral apical): 21 (38.9%); type V (APA unilateral mix): 2 (3.7%). APA origin were from inferior epigastric artery (IEA): 7 (9.5%); from inferior vesical artery (IVA): 32 (43.2%); from obturator artery (OA): 35 (47.3%). Conclusion: A precise angioanatomic evalutation of arteries destined to the penis by MR angiography pre-operation for male pelvic organs will help surgeons to preserve them and contributes to reduce the erectile dysfunction after these procedures

  12. Excess of Aminopeptidase A in the Brain Elevates Blood Pressure via the Angiotensin II Type 1 and Bradykinin B2 Receptors without Dipsogenic Effect

    Directory of Open Access Journals (Sweden)

    Takuto Nakamura

    2017-01-01

    Full Text Available Aminopeptidase A (APA cleaves angiotensin (Ang II, kallidin, and other related peptides. In the brain, it activates the renin angiotensin system and causes hypertension. Limited data are available on the dipsogenic effect of APA and pressor effect of degraded peptides of APA such as bradykinin. Wistar-Kyoto rats received intracerebroventricular (icv APA in a conscious, unrestrained state after pretreatment with (i vehicle, (ii 80 μg of telmisartan, an Ang II type-1 (AT1 receptor blocker, (iii 800 nmol of amastatin, an aminopeptidase inhibitor, and (iv 1 nmol of HOE-140, a bradykinin B2 receptor blocker. Icv administration of 400 and 800 ng of APA increased blood pressure by 12.6 ± 3.0 and 19.0 ± 3.1 mmHg, respectively. APA did not evoke drinking behavior. Pressor response to APA was attenuated on pretreatment with telmisartan (vehicle: 22.1 ± 2.2 mmHg versus telmisartan: 10.4 ± 3.2 mmHg. Pressor response to APA was also attenuated with amastatin and HOE-140 (vehicle: 26.5 ± 1.1 mmHg, amastatin: 14.4 ± 4.2 mmHg, HOE-140: 16.4 ± 2.2 mmHg. In conclusion, APA increase in the brain evokes a pressor response via enzymatic activity without dipsogenic effect. AT1 receptors and B2 receptors in the brain may contribute to the APA-induced pressor response.

  13. Pelvic magnetic resonance imaging angioanatomy of the arterial blood supply to the penis in suspected prostate cancer patients

    Energy Technology Data Exchange (ETDEWEB)

    Thai, Cao Tan, E-mail: bstanhatinh@gmail.com [Department of Urology, Brabois Hospital, University Hospital of Nancy, Rue du Morvan, 54500 Vandoeuvre Lès Nancy Cedex (France); IADI Laboratory, INSERM-U947, Brabois Hospital, University Hospital of Nancy, Tour Drouet, rue du Morvan, 54511 Vandoeuvre Lès Nancy Cedex (France); Karam, Ibrahim Michel [Clinical Epidemiology and Evaluation Department, University Hospital of Nancy (France); Department of Anatomy, Faculty of Medicine Nancy, 9 Avenue de la Foret de haye BP, 54505 Vandoeuvre Lès Nancy Cedex (France); Nguyen-Thi, Phi Linh [Clinical Epidemiology and Evaluation Department, University Hospital of Nancy (France); INSERM, CIC-EC CIE6, 92 Avenue du Maréchal de Lattre de Tassigny, 54000 Nancy (France); Lefèvre, Frédéric [Department of Radiology, Brabois Hospital, University Hospital of Nancy, Rue du Morvan, 54500 Vandoeuvre Lès Nancy Cedex (France); Hubert, Jacques [Department of Urology, Brabois Hospital, University Hospital of Nancy, Rue du Morvan, 54500 Vandoeuvre Lès Nancy Cedex (France); IADI Laboratory, INSERM-U947, Brabois Hospital, University Hospital of Nancy, Tour Drouet, rue du Morvan, 54511 Vandoeuvre Lès Nancy Cedex (France); Felblinger, Jacques [IADI Laboratory, INSERM-U947, Brabois Hospital, University Hospital of Nancy, Tour Drouet, rue du Morvan, 54511 Vandoeuvre Lès Nancy Cedex (France); Eschwège, Pascal [Department of Urology, Brabois Hospital, University Hospital of Nancy, Rue du Morvan, 54500 Vandoeuvre Lès Nancy Cedex (France)

    2015-05-15

    Highlights: • Three patterns of penile arterial supply (according to the classification of Stéphane Droupy). • Our classification about accessory pudendal artery. • Origin of accessory pudendal artery. - Abstract: Purpose: To describe the internal pudendal artery (IPA) and accessory pudendal artery (APA) detected by magnetic resonance (MR) angiography to help surgeons to find and preserve them during radical prostatectomy (RP). Materials and methods: Constrast-enhanced MR 3.0 T angiography of the pelvis were performed in 111 male patients suspected diagnosis of prostate cancer (PCa), and describe the penile arterial blood supply. Results: There are three patterns of the arterial blood supply to the penis (IPA and/or APA) accounting for 51.4%, 46.8% and 1.8% of cases, respectively. About the accessory pudendal artery (APA): 54/111 (48.6%) patients had APA with five different branching patterns, they were type I (APA bilateral symmetry): 17 (31.5%); type II (APA bilateral asymmetry): 1 (1.9%); type III (APA unilateral lateral): 13 (24%); type IV (APA unilateral apical): 21 (38.9%); type V (APA unilateral mix): 2 (3.7%). APA origin were from inferior epigastric artery (IEA): 7 (9.5%); from inferior vesical artery (IVA): 32 (43.2%); from obturator artery (OA): 35 (47.3%). Conclusion: A precise angioanatomic evalutation of arteries destined to the penis by MR angiography pre-operation for male pelvic organs will help surgeons to preserve them and contributes to reduce the erectile dysfunction after these procedures.

  14. Transcriptome dynamics through alternative polyadenylation in developmental and environmental responses in plants revealed by deep sequencing.

    Science.gov (United States)

    Shen, Yingjia; Venu, R C; Nobuta, Kan; Wu, Xiaohui; Notibala, Varun; Demirci, Caghan; Meyers, Blake C; Wang, Guo-Liang; Ji, Guoli; Li, Qingshun Q

    2011-09-01

    Polyadenylation sites mark the ends of mRNA transcripts. Alternative polyadenylation (APA) may alter sequence elements and/or the coding capacity of transcripts, a mechanism that has been demonstrated to regulate gene expression and transcriptome diversity. To study the role of APA in transcriptome dynamics, we analyzed a large-scale data set of RNA "tags" that signify poly(A) sites and expression levels of mRNA. These tags were derived from a wide range of tissues and developmental stages that were mutated or exposed to environmental treatments, and generated using digital gene expression (DGE)-based protocols of the massively parallel signature sequencing (MPSS-DGE) and the Illumina sequencing-by-synthesis (SBS-DGE) sequencing platforms. The data offer a global view of APA and how it contributes to transcriptome dynamics. Upon analysis of these data, we found that ∼60% of Arabidopsis genes have multiple poly(A) sites. Likewise, ∼47% and 82% of rice genes use APA, supported by MPSS-DGE and SBS-DGE tags, respectively. In both species, ∼49%-66% of APA events were mapped upstream of annotated stop codons. Interestingly, 10% of the transcriptomes are made up of APA transcripts that are differentially distributed among developmental stages and in tissues responding to environmental stresses, providing an additional level of transcriptome dynamics. Examples of pollen-specific APA switching and salicylic acid treatment-specific APA clearly demonstrated such dynamics. The significance of these APAs is more evident in the 3034 genes that have conserved APA events between rice and Arabidopsis.

  15. Presence and patterns of alkaline phosphatase activity and phosphorus cycling in natural riparian zones under changing nutrient conditions

    Directory of Open Access Journals (Sweden)

    Peifang Wang

    2014-08-01

    Full Text Available Phosphorus (P is an important limiting nutrient in aquatic ecosystems and knowledge of P cycling is fundamental for reducing harmful algae blooms and other negative effects in water. Despite their importance, the characteristics of P cycling under changing nutrient conditions in shallow lakes were poorly investigated. In this study, in situ incubation experiments were conducted in a natural riparian zone in the main diversion channel used for water transfer into Lake Taihu (Wangyu River. Variations in microbial biomass, dissolved P fractions (organic and inorganic, and alkaline phosphatase activity (bulk APA and specific APA were determined after incubation with and without the addition of P and nitrogen (N (4 total water treatments: +P, +N, +NP, and control. Experiments were conducted during two seasons (late spring and early fall to account for natural differences in nutrient levels that may occur in situ. Our results demonstrated that low levels of DRP may not necessarily indicate P limitation. Phytoplankton exhibited “serial N limitation with P stress” in May, such that chlorophyll a (Chl a increased significantly with N addition, while the limiting nutrient shifted to P in October and phytoplankton biomass increased with P addition. Phytoplankton contributed greatly to APA production and was significantly influenced by P bioavailability, yet high levels of bulk APA were also not necessarily indicative of P limitation. In contrast to phytoplankton, bacteria were less P stressed. As a consequence of enhanced utilization of dissolved reactive P (DRP and dissolved organic P (DOP, +N treatment elevated APA significantly. By contrast, APA could be repressed to low values and phytoplankton converted a large portion of DRP to DOP with P addition. But this was not consistent with bacteria APA (bact-APA in the absence or presence of abundant phytoplankton biomass. The correlation between bulk APA and DRP was good at separate sites and discrepant

  16. Protocol to assess the neurophysiology associated with multi-segmental postural coordination

    International Nuclear Information System (INIS)

    Lomond, Karen V; Henry, Sharon M; Jacobs, Jesse V; Hitt, Juvena R; Horak, Fay B; Cohen, Rajal G; Schwartz, Daniel; Dumas, Julie A; Naylor, Magdalena R; Watts, Richard; DeSarno, Michael J

    2013-01-01

    Anticipatory postural adjustments (APAs) stabilize potential disturbances to posture caused by movement. Impaired APAs are common with disease and injury. Brain functions associated with generating APAs remain uncertain due to a lack of paired tasks that require similar limb motion from similar postural orientations, but differ in eliciting an APA while also being compatible with brain imaging techniques (e.g., functional magnetic resonance imaging; fMRI). This study developed fMRI-compatible tasks differentiated by the presence or absence of APAs during leg movement. Eighteen healthy subjects performed two leg movement tasks, supported leg raise (SLR) and unsupported leg raise (ULR), to elicit isolated limb motion (no APA) versus multi-segmental coordination patterns (including APA), respectively. Ground reaction forces under the feet and electromyographic activation amplitudes were assessed to determine the coordination strategy elicited for each task. Results demonstrated that the ULR task elicited a multi-segmental coordination that was either minimized or absent in the SLR task, indicating that it would serve as an adequate control task for fMRI protocols. A pilot study with a single subject performing each task in an MRI scanner demonstrated minimal head movement in both tasks and brain activation patterns consistent with an isolated limb movement for the SLR task versus multi-segmental postural coordination for the ULR task. (note)

  17. Dynamic Analyses of Alternative Polyadenylation from RNA-Seq Reveal 3′-UTR Landscape Across 7 Tumor Types

    Science.gov (United States)

    Xia, Zheng; Donehower, Lawrence A; Cooper, Thomas A.; Neilson, Joel R.; Wheeler, David A.; Wagner, Eric J.; Li, Wei

    2015-01-01

    Alternative polyadenylation (APA) is a pervasive mechanism in the regulation of most human genes, and its implication in diseases including cancer is only beginning to be appreciated. Since conventional APA profiling has not been widely adopted, global cancer APA studies are very limited. Here we develop a novel bioinformatics algorithm (DaPars) for the de novo identification of dynamic APAs from standard RNA-seq. When applied to 358 TCGA Pan-Cancer tumor/normal pairs across 7 tumor types, DaPars reveals 1,346 genes with recurrent and tumor-specific APAs. Most APA genes (91%) have shorter 3′ UTRs in tumors that can avoid miRNA-mediated repression, including glutaminase (GLS), a key metabolic enzyme for tumor proliferation. Interestingly, selected APA events add strong prognostic power beyond common clinical and molecular variables, suggesting their potential as novel prognostic biomarkers. Finally, our results implicate CstF64, an essential polyadenylation factor, as a master regulator of 3′ UTR shortening across multiple tumor types. PMID:25409906

  18. Alaska Power Administration combined financial statements, schedules, and supplemental reports, September 30, 1997 and 1996 with independent auditors` report thereon

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-04-01

    The Alaska Power Administration (APA) will continue to encourage economic and industrial development in Alaska through implementing the sale of APA assets in a manner consistent with the authorizing legislation while balancing all the stakeholders` interests. Alaska Power Administration will provide their employees opportunities for successful career transitions and conduct an efficient transfer of assets and closeout of APA, while continuing to provide customers reliable, low-cost hydroelectric energy during the transition. The attached report presents the results of the independent certified public accounts` audit of the Alaska Power Administration`s (APA) combined power system statements of assets; Federal investment and liabilities; and the related combined statements of revenues, expenses and accumulated net revenues, and cash flows. The auditors` reports on APA`s internal control structure and compliance with laws and regulations disclosed no reportable conditions or instances of noncompliance. Based on the unqualified opinion of the independent public accounting firm of KPMG Peak Marwick LLP and review of their audit work, the authors believe the financial statements fairly present the financial condition and results of the operations of APA for the period under audit.

  19. Phenotypic overlap in hypertrophic cardiomyopathy: apical hypertrophy, midventricular obstruction, and apical aneurysm.

    Science.gov (United States)

    Minami, Yuichiro; Haruki, Shintaro; Hagiwara, Nobuhisa

    2014-12-01

    Within the diverse phenotypic spectrum of hypertrophic cardiomyopathy (HCM), subgroups of patients with apical hypertrophy (APH), midventricular obstruction (MVO), and apical aneurysm (APA) have emerged. While previous studies have suggested the existence of considerable overlap between APH, MVO, and APA, there are still many unanswered questions. Therefore, we attempted to clarify the relationship of the above three phenotypes of HCM with respect to prevalence, overlap, and outcomes. Among the 544 study HCM patients (mean follow-up period: 11.6±7.4 years), 170 with APH (31.3%), 51 with MVO (9.4%), and 24 with APA (4.4%) were examined. There was phenotypic overlap between APH and MVO in 17 patients, APH and APA in 14 patients, and MVO and APA in 14 patients. Furthermore, a combination of APH, MVO, and APA was observed in eight patients. Detailed analysis of the relationship between overlapping phenotypes and the prognosis showed that APA patients without a history of APH had an extremely poor outcome (probability of the combined endpoint of sudden death and potentially lethal arrhythmic events ≥50%). Conversely, APH patients without MVO had a strikingly good outcome (probability of the combined endpoint <5%). Other patients had an intermediate outcome (probability of the combined endpoint 10-40%). Our results suggest that overlap between these three forms of HCM is substantial, and that detailed classification of the overlapping phenotypes is clinically meaningful. Copyright © 2014 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.

  20. Variations of alkaline phosphatase activity and P fractions in sediments of a shallow Chinese eutrophic lake (Lake Taihu)

    International Nuclear Information System (INIS)

    Zhang Tingxi; Wang Xiaorong; Jin Xiangcan

    2007-01-01

    The distribution of alkaline phosphatase activity (APA) and P fractions in sediment cores and the relationship between them were studied in a shallow Chinese freshwater lake (Lake Taihu). Sediment cores were collected from four sites, characterized by different degrees of eutrophication in June 2004. Sediment P was fractionated into Fe/Al-P, Ca-P, organic P (OP), inorganic P (IP) and total P (TP). The former two species made the largest contribution to the sediment P pool. Results show that trophic status and hydrological conditions have great impact on the APA of the sediments. The order of the APA in sediments was conjectured to be: macrophyte dominated lake > transitional lake > algal dominated lake. APA profiles follow a similar downcore decreasing trend. There was a positive relationship between the APA and the TP, IP. The multiple linear regression equation of the APA and P fractions is: APA = -97 + 0.768TP - 0.985Fe/Al-P. - Characteristics of the alkaline phosphatase activity and P fractions in sediments of different trophic status lake were studied in Lake Taihu

  1. [Evaluation of the feasibility of a program of adapted physical activity in day hospital of digestive oncology: From the point of view of patients].

    Science.gov (United States)

    Crespel, Céline; Brami, Cloé; de Boissieu, Paul; Mazza, Camille; Chauvet, Kevin; Lemoine, Amélie; Gavlak, Benoit; Léandri, Chloé; Brasseur, Mathilde; Bertin, Eric; Bouché, Olivier

    2018-02-06

    Adapted physical activity (APA) is recognized as an effective supportive care for asthenia and quality of life in oncology. Before an APA program was organized, the feasibility of such a program was evaluated among the patients. Descriptive, prospective, semi-qualitative, single-center study over a 3-month period in patients treated with ambulatory chemotherapy for digestive cancer. A self-questionnaire was offered to all patients to evaluate their practice and knowledge about APA. In ten patients, fatigue, anxiety and depression were assessed, before and after 9 weeks of hospital-based APA. The scores were compared by matched Student test. Of the 123 patients treated, 80 questionnaires (65%) were exploitable. Before the diagnosis of cancer, 40 patients (50%) were physically active, 20% after (n=16). The reasons for not practicing were: lack of interest/not the idea (42%), lack of time (34%), do not believe in profit (9%), too expensive (8%). Fifty-three patients (66%) were interested in the program. In 10 patients, the APA program significantly reduced the depression score (P=0.024) and a non-significant improvement in anxiety and fatigue. This study shows that patients treated with chemotherapy are unaware of the usefulness of APA and that medical information can improve adherence to such a program. The establishment of an intra-hospital APA program proved to be possible and relevant. Copyright © 2018 Société Française du Cancer. Published by Elsevier Masson SAS. All rights reserved.

  2. Alkaline phosphatase activity and its relationship to inorganic phosphorus in the transition zone of the North-western African upwelling system

    Science.gov (United States)

    Sebastián, Marta; Arístegui, Javier; Montero, María F.; Escanez, Jose; Xavier Niell, F.

    2004-08-01

    The enzymatic activity of alkaline phosphatase (APA) was studied in the transition zone between the African upwelling system and the open ocean waters of the Canary Islands region. This region is recurrently dominated by the presence of upwelling filaments that may transport nutrient-enriched waters out into the open ocean before nutrients become exhausted by plankton. Turnover rates by APA were generally low in the whole region, but detectable in all the measurements carried out. On average, turnover rates were higher in the upwelling stations, and APA in those waters seemed to be mainly generated by heterotrophic bacteria to supply easily assimilable organic C. APA outside the upwelling area showed an inverse hyperbolic relationship with increasing phosphate, suggesting the presence of both constitutive and Pi-inducible APA. In these offshore waters, a threshold of 0.1 μM of phosphate could be defined for the regulatory function of Pi on APA. Thus, APA in nutrient-poor waters seemed to be induced to compensate for Pi-deficiency. Turnover rates in the filaments showed basal (probably constitutive) levels, whereas they increased in the surrounding waters, where phosphate concentration presumably did not satisfy plankton P-demands. The fertilising effect of the filaments and associated cyclonic eddies extended to at least 175 km offshore, where basal alkaline phosphatase activities were still found. The magnitude of this effect depends probably on the intensity of upwelling events and the degree of recirculation of filament water back to the coastal jet.

  3. Should title lengths really adhere to the American Psychological Association's twelve word limit?

    Science.gov (United States)

    Hallock, Robert M; Dillner, Kari M

    2016-04-01

    The publication manual for the American Psychological Association (APA) suggests that title lengths do not exceed 12 words, yet journals do not prevent longer titles. Here, we examined title lengths in APA journals to see how many exceeded the APA's suggested limit. First, we conducted a systematic analysis of 235 articles in the current issues of 23 APA journals. A total of 52% of titles were more than 12 words long. Second, we examined articles from APA journals that were at least 50 years old to examine whether title lengths have changed over time. Our results suggested that the average title lengths have indeed increased with time. One of 2 courses should be taken. Perhaps science is becoming more complex that longer titles are needed in order to convey the primary message to the reader. If this is the case, then the APA's word limit should be increased. On the other hand, however, maybe editor and reviewers should try to enforce the current word limit to force writers to be succinct. Either way, editors should make their preferences clear so that the trend for longer titles does not continue unchecked. (c) 2016 APA, all rights reserved).

  4. Segmentation of the Himalayas as revealed by arc-parallel gravity anomalies

    Science.gov (United States)

    Hetényi, György; Cattin, Rodolphe; Berthet, Théo; Le Moigne, Nicolas; Chophel, Jamyang; Lechmann, Sarah; Hammer, Paul; Drukpa, Dowchu; Sapkota, Soma Nath; Gautier, Stéphanie; Thinley, Kinzang

    2016-09-01

    Lateral variations along the Himalayan arc are suggested by an increasing number of studies and carry important information about the orogen’s segmentation. Here we compile the hitherto most complete land gravity dataset in the region which enables the currently highest resolution plausible analysis. To study lateral variations in collisional structure we compute arc-parallel gravity anomalies (APaGA) by subtracting the average arc-perpendicular profile from our dataset; we compute likewise for topography (APaTA). We find no direct correlation between APaGA, APaTA and background seismicity, as suggested in oceanic subduction context. In the Himalayas APaTA mainly reflect relief and erosional effects, whereas APaGA reflect the deep structure of the orogen with clear lateral boundaries. Four segments are outlined and have disparate flexural geometry: NE India, Bhutan, Nepal & India until Dehradun, and NW India. The segment boundaries in the India plate are related to inherited structures, and the boundaries of the Shillong block are highlighted by seismic activity. We find that large earthquakes of the past millennium do not propagate across the segment boundaries defined by APaGA, therefore these seem to set limits for potential rupture of megathrust earthquakes.

  5. Genotype-Specific Steroid Profiles Associated With Aldosterone-Producing Adenomas.

    Science.gov (United States)

    Williams, Tracy Ann; Peitzsch, Mirko; Dietz, Anna S; Dekkers, Tanja; Bidlingmaier, Martin; Riester, Anna; Treitl, Marcus; Rhayem, Yara; Beuschlein, Felix; Lenders, Jacques W M; Deinum, Jaap; Eisenhofer, Graeme; Reincke, Martin

    2016-01-01

    Primary aldosteronism comprises 2 main subtypes: unilateral aldosterone-producing adenoma (APA) and bilateral adrenal hyperplasia. Somatic KCNJ5 mutations are found in APA at a prevalence of around 40% that drive and sustain aldosterone excess. Somatic APA mutations have been described in other genes (CACNA1D, ATP1A1, and ATP2B3) albeit at a lower frequency. Our objective was to identify genotype-specific steroid profiles in adrenal venous (AV) and peripheral venous (PV) plasma in patients with APAs. We measured the concentrations of 15 steroids in AV and PV plasma samples by liquid chromatography-tandem mass spectrometry from 79 patients with confirmed unilateral primary aldosteronism. AV sampling lateralization ratios of steroids normalized either to cortisol or to DHEA+androstenedione were also calculated. The hybrid steroid 18-oxocortisol exhibited 18- and 16-fold higher concentrations in lateralized AV and PV plasma, respectively, from APA with KCNJ5 mutations compared with all other APA combined together (P<0.001). Lateralization ratios for the KCNJ5 group were also generally higher. Strikingly, we demonstrate that a distinct steroid signature can differentiate APA genotype in AV and PV plasma. Notably, a 7-steroid fingerprint in PV plasma correctly classified 92% of the APA according to genotype. Prospective studies are necessary to translate these findings into clinical practice and determine if steroid fingerprinting could be of value to select patients with primary aldosteronism who are particularly suitable candidates for adrenal venous sampling because of a high probability of having an APA. © 2015 American Heart Association, Inc.

  6. Characterising antimicrobial protein-membrane complexes

    International Nuclear Information System (INIS)

    Xun, Gloria; Dingley, Andrew; Tremouilhac, Pierre

    2009-01-01

    Full text: Antimicrobial proteins (AMPs) are host defence molecules that protect organisms from microbial infection. A number of hypotheses for AMP activity have been proposed which involve protein membrane interactions. However, there is a paucity of information describing AMP-membrane complexes in detail. The aim of this project is to characterise the interactions of amoebapore-A (APA-1) with membrane models using primarily solution-state NMR spectroscopy. APA-1 is an AMP which is regulated by a pH-dependent dimerisation event. Based on the atomic resolution solution structure of monomeric APA-1, it is proposed that this dimerisation is a prerequisite for ring-like hexameric pore formation. Due to the cytotoxicity of APA-1, we have developed a cell-free system to produce this protein. To facilitate our studies, we have adapted the cell-free system to isotope label APA-1. 13 C /15 N -enriched APA-1 sample was achieved and we have begun characterising APA-1 dimerisation and membrane interactions using NMR spectroscopy and other biochemical/biophysical methods. Neutron reflectometry is a surface-sensitive technique and therefore represents an ideal technique to probe how APA-1 interacts with membranes at the molecular level under different physiological conditions. Using Platypus, the pH-induced APA-1-membrane interactions should be detectable as an increase of the amount of protein adsorbed at the membrane surface and changes in the membrane properties. Specifically, detailed information of the structure and dimensions of the protein-membrane complex, the position and amount of the protein in the membrane, and the perturbation of the membrane phospholipids on protein incorporation can be extracted from the neutron reflectometry measurement. Such information will enable critical assessment of current proposed mechanisms of AMP activity in bacterial membranes and complement our NMR studies

  7. The obstetric outcome following treatment in a cohort of patients with antiphospholipid antibody syndrome in a tertiary care center

    Directory of Open Access Journals (Sweden)

    V Dadhwal

    2011-01-01

    Full Text Available Background: Antiphospholipid antibody syndrome (APAS is regarded as the most frequently acquired risk factor for thrombophilia. The obstetric manifestations of APAS include early or late pregnancy losses and complications like preeclampsia and fetal growth restriction. Its timely diagnosis and treatment can improve maternal and neonatal outcome. Aims: To study the pregnancy outcome of patients with APAS treated with heparin and aspirin. Settings and Design: This was a retrospective study of pregnancy outcome in 42 consecutive women with APAS, treated with heparin and aspirin. Materials and Methods: The case records of 42 diagnosed cases of APAS with pregnancy, over a 3-year period, were studied. The pregnancy outcome in this group was compared before and after treatment with heparin and low-dose aspirin in terms of abortions, intrauterine deaths and live birth rate. The outcome of the present pregnancy in terms of fetal and maternal complications was analyzed. Results: The mean age and average parity of women with APAS were 30.1±4.1 years and 3.2±1.2, respectively. Among the treated patients of APAS, 13 (30.9% had preeclampsia and 9 (21.4% had intrauterine growth restriction (IUGR. There were 2 (4.7% intrauterine deaths, 4 (9.5% missed abortions and 3 (7.1% abruptio placentae. Women with APAS had a live birth rate of 4.6% before treatment and 85.7% in the index pregnancy after treatment. Conclusion: Treatment of pregnant women with APAS results in marked improvement in the live birth rate (4.6-85.7%. However, complications like preeclampsia and IUGR occur even after treatment, requiring strict monitoring and timely delivery.

  8. Diagnostic value of amplitude-phase analysis in myocardial infarct. Comparison with thallium perfusion scintigraphy and contrast ventrilography

    International Nuclear Information System (INIS)

    Garcheva, M.; Trindev, P.; Shejretova, E.; Stoyanova, N.; Kaloyanova, P.; Khadzhikostova, Kh.

    1990-01-01

    The evaluation is based on the results of investigation of 34 patients who have had myocardial infarct without rhythm disturbances. Compared to contrast ventrilography, the amplitude-phase analysis (APA) of 'rest' radionuclide ventrilography show 80% sensitivity and 100% specificity, as well as high accuracy in determination of the type and localization of the kinetic disturbances. The comparison with the thallium perfusion scintigraphy demonstrates the possibility of APA to vizualize abnormal kinetic area of the myocardial wall and shows its independent significance in the cases of doubtful findings. APA is a powerful tool for unambigious differentiating of hypokinetic from akinetic and diskinetic areas. 1 tab., 1 fig., 4 refs

  9. Creating healthier workplaces: The American Psychological Association/National Institute of Occupational Safety and Health cooperative agreement. Introduction and historical overview.

    Science.gov (United States)

    Quick, J C; Camara, W J; Johnson, J V; Sauter, S L; Hurrell, J J; Piotrkowski, C S; Spielberger, C D

    1997-01-01

    This article introduces the special section on the American Psychological Association/National Institute for Occupational Safety and Health (APA/NIOSH) collaboration. The section includes an overview statement of National Institute for Occupational Safety and Health research by Linda Rosenstock and 5 competitively peer-reviewed articles submitted to the Journal of Occupational Health Psychology following their presentation in an earlier form at the 3rd APA/NIOSH conference in September 1995. This article provides a brief history of the APA/NIOSH collaboration forged at the turn of this decade.

  10. Female sex hormones are associated with the reduction of serum sodium and hypertension complications in patients with aldosterone-producing adenoma.

    Science.gov (United States)

    Lu, Zhao-Hui; Zhu, Xiao-Xiao; Tang, Zhi-qing; Yang, Guo-Qing; Du, Jin; Wang, Xian-Ling; Yang, Jin-Zhi Ou; Gu, Wei-Jun; Guo, Qing-Hua; Jin, Nan; Yang, Li-Juan; Ba, Jian-Ming; Dou, Jing-Tao; Mu, Yi-Ming

    2013-01-01

    This study was conducted to evaluate gender-related differences in clinical characteristics and vascular complications in patients with aldosterone-producing adenomas (APA). Clinical characteristics, biochemical markers and incidence of vascular complications were compared by gender in 187 consecutive patients with APA confirmed by pathological diagnosis. Patients were separated into two groups based on ages either older or younger than 49 years, the average age of menopause among Chinese women (y and ≥49 y). Males had significantly higher BMI than females in the age group of hormones are implicated in reducing serum sodium concentration and vascular complications in female APA patients.

  11. ¿Existe relación entre la concentración de inducción anestésica de sevofluorano y la incidencia de agitación postanestésica en niños?

    OpenAIRE

    Alejandro González Arellano; Nicolás Aeschlimann; Augusto Rolle; Pamela Chomali; Laura Gebauer; Mauricio Ibacache

    2017-01-01

    Introducción. La inducción anestésica con sevofluorano se asocia con agitación postanestésica (APA) en niños. Concentraciones de sevofluorano mayores a 6% producen actividad cerebral epileptiforme, la que podría estar relacionada a APA. El propósito de este estudio fue comparar el efecto de dos diferentes concentraciones de inducción anestésica con sevofluorano sobre la incidencia de APA, en niños sometidos a cirugía infraumbilical. Método. Estudio prospectivo y doble ciego, en pacientes ...

  12. Kinetic studies on the carboxylation of 6-amino-penicillanic acid to 8-hydroxy-penillic acid

    DEFF Research Database (Denmark)

    Henriksen, Claus Maxel; Holm, SS; Schipper, D.

    1997-01-01

    The carboxylation in aqueous solution of 6-amino-penicillanic acid (6-APA) to 8-hydroxy-penillic acid (8-HPA) was studied at 25 degrees C and pH 6.5. During sparging with either a citrate buffer or a chemically defined cultivation medium containing 6-APA with mixtures of carbon dioxide and air (2....... Formation of the unknown compound was not observed in the cultivation medium. The carboxylation of 6-APA was also found to be first order with respect to the concentration of dissolved carbon dioxide. The rate constant for formation of 8-HPA did not differ significantly in the cultivation medium compared...

  13. Vitamin D receptor gene variants in Parkinson’s disease patients

    Directory of Open Access Journals (Sweden)

    Rokhsareh Meamar

    2017-07-01

    Conclusion: This study demonstrates a possible association between the VDR FokI and ApaI polymorphism and PD, indicating that VDR polymorphisms may change genetic susceptibility to sporadic PD in the Iranian population.

  14. What Is Psychiatry?

    Medline Plus

    Full Text Available ... Join APA General Members Residents and Fellows Medical Students International Become a ... © 2018 American Psychiatric Association. All Rights Reserved. 800 Maine Avenue, S.W., Suite ...

  15. Helping Yourself Heal: A Recovering Man's Guide to Coping with the Effects of Childhood Abuse

    Science.gov (United States)

    ... Information, http: / / www. healthyminds. org ■ American Psychological Association Psychology Help Center, http: / / www. apa. org/ helpcenter/ index. ... 410-893-3322 8 Notes ____________________________________________________ ____________________________________________________ ____________________________________________________ ____________________________________________________ ____________________________________________________ ____________________________________________________ ____________________________________________________ ____________________________________________________ ____________________________________________________ ____________________________________________________ ____________________________________________________ ____________________________________________________ ____________________________________________________ ____________________________________________________ ____________________________________________________ ____________________________________________________ ____________________________________________________ [Room here for clinic sticker and list of local resources] HHS Publication ...

  16. Alterations in polyadenylation and its implications for endocrine disease

    DEFF Research Database (Denmark)

    Rehfeld, Anders Aagaard; Plass, Mireya; Krogh, Anders

    2013-01-01

    Introduction: Polyadenylation is the process in which the pre-mRNA is cleaved at the poly(A) site and a poly(A) tail is added - a process necessary for normal mRNA formation. Genes with multiple poly(A) sites can undergo alternative polyadenylation (APA), producing distinct mRNA isoforms with dif......Introduction: Polyadenylation is the process in which the pre-mRNA is cleaved at the poly(A) site and a poly(A) tail is added - a process necessary for normal mRNA formation. Genes with multiple poly(A) sites can undergo alternative polyadenylation (APA), producing distinct mRNA isoforms...... with different 3' untranslated regions (3' UTRs) and in some cases different coding regions. Two thirds of all human genes undergo APA. The efficiency of the polyadenylation process regulates gene expression and APA plays an important part in post-transcriptional regulation, as the 3' UTR contains various cis...

  17. Harnessing two language games to enhance students' achievement ...

    African Journals Online (AJOL)

    SS1) students' achievement in English vocabulary in Apa Local Government Area of Benue State. The study was carried out to determine whether puzzle and scramble games strategies would improve students' achievement in English ...

  18. Evaluation of anti-pneumococcal capsular antibodies as adjunctive therapy in experimental pneumococcal meningitis

    DEFF Research Database (Denmark)

    Brandt, Christian; Frimodt-Moller, N; Lundgren, Jens Dilling

    2006-01-01

    OBJECTIVE: Bacteraemia concomitant with meningitis has been shown to greatly affect outcome. Consequently, the efficacy of serotype-specific anti-pneumococcal antiserum (APAS) was investigated in a rat model of pneumococcal meningitis. METHODS: Rats were infected with Streptococcus pneumoniae...... serotype 3. All rats received ceftriaxone starting 26 h post-infection. APAS was administered either at the time of infection or 26 h post-infection and effects were compared with rats treated with antibiotics only. RESULTS AND CONCLUSION: A significant clinical benefit was found when APAS was given...... at the time of infection whereas no effect was found when administered 26 h after infection. This work indicates that the clinical value of using APAS in pneumococcal meningitis may be limited...

  19. UPF2-dependent nonsense-mediated mRNA decay pathway is essential for spermatogenesis by selectively eliminating longer 3'UTR transcripts

    DEFF Research Database (Denmark)

    Bao, Jianqiang; Vitting-Seerup, Kristoffer; Waage, Johannes Eichler

    2016-01-01

    During transcription, most eukaryotic genes generate multiple alternative cleavage and polyadenylation (APA) sites, leading to the production of transcript isoforms with variable lengths in the 3' untranslated region (3'UTR). In contrast to somatic cells, male germ cells, especially pachytene...

  20. Zimbabwe Journal of Educational Research: Submissions

    African Journals Online (AJOL)

    ZJER) recommends the use of the latest edition of the American Psychological Association (APA) for all citations and references. Reference entries for books. Vasi, A. C. (2010). A history of research methods: Trends in Zimbabwean education.

  1. What Is Psychiatry?

    Medline Plus

    Full Text Available ... Psychiatrists Residents & Medical Students Patients & Families About APA Work At ... © 2018 American Psychiatric Association. All Rights Reserved. 800 Maine Avenue, S.W., Suite 900, Washington, ...

  2. Probability as certainty: dichotomous thinking and the misuse of p values.

    Science.gov (United States)

    Hoekstra, Rink; Finch, Sue; Kiers, Henk A L; Johnson, Addie

    2006-12-01

    Significance testing is widely used and often criticized. The Task Force on Statistical Inference of the American Psychological Association (TFSI, APA; Wilkinson & TFSI, 1999) addressed the use of significance testing and made recommendations that were incorporated in the fifth edition of the APA Publication Manual (APA, 2001). They emphasized the interpretation of significance testing and the importance of reporting confidence intervals and effect sizes. We examined whether 286 Psychonomic Bulletin & Review articles submitted before and after the publication of the TFSI recommendations by APA complied with these recommendations. Interpretation errors when using significance testing were still made frequently, and the new prescriptions were not yet followed on a large scale. Changing the practice of reporting statistics seems doomed to be a slow process.

  3. 78 FR 25384 - Standard Instrument Approach Procedures, and Takeoff Minimums and Obstacle Departure Procedures...

    Science.gov (United States)

    2013-05-01

    ... from: 1. FAA Public Inquiry Center (APA-200), FAA Headquarters Building, 800 Independence Avenue SW..., in addition to their complex nature and the need for a special format make publication in the Federal...

  4. Evaluation of Surface Treatment Methods on the Bond Strength of Zirconia Ceramics Systems, Resin Cements and Tooth Surface

    Directory of Open Access Journals (Sweden)

    Akkuş Emek

    2015-07-01

    Full Text Available Objectives: To compare the effects of airborne-particle abrasion (APA and tribochemical silica coating (TSC surface treatment methods on the shear bond strength of zirconia ceramics systems, resin cements and tooth surface

  5. 76 FR 52237 - Standard Instrument Approach Procedures, and Takeoff Minimums and Obstacle Departure Procedures...

    Science.gov (United States)

    2011-08-22

    ..., individual SIAP and Takeoff Minimums and ODP copies may be obtained from: 1. FAA Public Inquiry Center (APA... SIAPs, their complex nature, and the need for a special format make their verbatim publication in the...

  6. 78 FR 56829 - Standard Instrument Approach Procedures, and Takeoff Minimums and Obstacle Departure Procedures...

    Science.gov (United States)

    2013-09-16

    ..., individual SIAP and Takeoff Minimums and ODP copies may be obtained from: 1. FAA Public Inquiry Center (APA... number of SIAPs, their complex nature, and the need for a special format make their verbatim publication...

  7. 77 FR 37799 - Standard Instrument Approach Procedures, and Takeoff Minimums and Obstacle Departure Procedures...

    Science.gov (United States)

    2012-06-25

    ..., individual SIAP and Takeoff Minimums and ODP copies may be obtained from: 1. FAA Public Inquiry Center (APA... number of SIAPs, their complex nature, and the need for a special format make their verbatim publication...

  8. 78 FR 68704 - Standard Instrument Approach Procedures, and Takeoff Minimums and Obstacle Departure Procedures...

    Science.gov (United States)

    2013-11-15

    ..., individual SIAP and Takeoff Minimums and ODP copies may be obtained from: 1. FAA Public Inquiry Center (APA... number of SIAPs, their complex nature, and the need for a special format make their verbatim publication...

  9. 77 FR 5694 - Standard Instrument Approach Procedures, and Takeoff Minimums and Obstacle Departure Procedures...

    Science.gov (United States)

    2012-02-06

    ..., individual SIAP and Takeoff Minimums and ODP copies may be obtained from: 1. FAA Public Inquiry Center (APA... large number of SIAPs, their complex nature, and the need for a special format make their verbatim...

  10. 77 FR 71494 - Standard Instrument Approach Procedures, and Takeoff Minimums and Obstacle Departure Procedures...

    Science.gov (United States)

    2012-12-03

    ..., individual SIAP and Takeoff Minimums and ODP copies may be obtained from: 1. FAA Public Inquiry Center (APA... number of SIAPs, their complex nature, and the need for a special format make their verbatim publication...

  11. 78 FR 50326 - Standard Instrument Approach Procedures, and Takeoff Minimums and Obstacle Departure Procedures...

    Science.gov (United States)

    2013-08-19

    ..., individual SIAP and Takeoff Minimums and ODP copies may be obtained from: 1. FAA Public Inquiry Center (APA... number of SIAPs, their complex nature, and the need for a special format make their verbatim publication...

  12. 78 FR 5253 - Standard Instrument Approach Procedures, and Takeoff Minimums and Obstacle Departure Procedures...

    Science.gov (United States)

    2013-01-25

    ... Minimums and ODP copies may be obtained from: 1. FAA Public Inquiry Center (APA-200), FAA Headquarters..., and the need for a special format make their verbatim publication in the Federal Register expensive...

  13. 77 FR 51896 - Standard Instrument Approach Procedures, and Takeoff Minimums and Obstacle Departure Procedures...

    Science.gov (United States)

    2012-08-28

    ..., individual SIAP and Takeoff Minimums and ODP copies may be obtained from: 1. FAA Public Inquiry Center (APA... number of SIAPs, their complex nature, and the need for a special format make their verbatim publication...

  14. 75 FR 72940 - Standard Instrument Approach Procedures, and Takeoff Minimums and Obstacle Departure Procedures...

    Science.gov (United States)

    2010-11-29

    ... Minimums and ODP copies may be obtained from: 1. FAA Public Inquiry Center (APA-200), FAA Headquarters..., and the need for a special format make their verbatim publication in the Federal Register expensive...

  15. 78 FR 32087 - Standard Instrument Approach Procedures, and Takeoff Minimums and Obstacle Departure Procedures...

    Science.gov (United States)

    2013-05-29

    ..., individual SIAP and Takeoff Minimums and ODP copies may be obtained from: 1. FAA Public Inquiry Center (APA... number of SIAPs, their complex nature, and the need for a special format make their verbatim publication...

  16. 78 FR 64172 - Standard Instrument Approach Procedures, and Takeoff Minimums and Obstacle Departure Procedures...

    Science.gov (United States)

    2013-10-28

    ... from: 1. FAA Public Inquiry Center (APA-200), FAA Headquarters Building, 800 Independence Avenue SW..., in addition to their complex nature and the need for a special format make publication in the Federal...

  17. 78 FR 64170 - Standard Instrument Approach Procedures, and Takeoff Minimums and Obstacle Departure Procedures...

    Science.gov (United States)

    2013-10-28

    ..., individual SIAP and Takeoff Minimums and ODP copies may be obtained from: 1. FAA Public Inquiry Center (APA... number of SIAPs, their complex nature, and the need for a special format make their verbatim publication...

  18. 78 FR 78714 - Standard Instrument Approach Procedures, and Takeoff Minimums and Obstacle Departure Procedures...

    Science.gov (United States)

    2013-12-27

    ..., individual SIAP and Takeoff Minimums and ODP copies may be obtained from: 1. FAA Public Inquiry Center (APA... number of SIAPs, their complex nature, and the need for a special format make their verbatim publication...

  19. 78 FR 64167 - Standard Instrument Approach Procedures, and Takeoff Minimums and Obstacle Departure Procedures...

    Science.gov (United States)

    2013-10-28

    ... from: 1. FAA Public Inquiry Center (APA-200), FAA Headquarters Building, 800 Independence Avenue SW..., in addition to their complex nature and the need for a special format make publication in the Federal...

  20. 77 FR 56762 - Standard Instrument Approach Procedures, and Takeoff Minimums and Obstacle Departure Procedures...

    Science.gov (United States)

    2012-09-14

    ..., individual SIAP and Takeoff Minimums and ODP copies may be obtained from: 1. FAA Public Inquiry Center (APA... number of SIAPs, their complex nature, and the need for a special format make their verbatim publication...