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Sample records for ao lenho mole

  1. Delimitação entre os lenhos juvenil e adulto de Pinus elliottii engelm

    Directory of Open Access Journals (Sweden)

    Gilmara Pires de Moura Palermo

    2013-02-01

    Full Text Available Durante o crescimento, as árvores produzem diferentes tipos de tecido lenhoso. O xilema produzido nos primeiros anos até certa idade cambial é denominado lenho juvenil e apresenta propriedades físicas, mecânicas, químicas e anatômicas diferentes do xilema produzido após certa idade cambial, isto é, quando as células do câmbio já amadureceram. Dessa forma, um prévio conhecimento sobre a qualidade da matéria-prima produzida é de fundamental importância para melhor aplicabilidade do material. Com base nesse contexto, este trabalho objetivou, a partir de dados de comprimento de traqueídeos e densidade da madeira, delimitar a idade de transição entre os lenhos juvenil e adulto. Para isso, coletaram-se três árvores de Pinus elliottii var. elliottii Engelm., com 35 anos de idade, provenientes da Estação Experimental de Itapetininga, localizada em São Paulo, Brasil. De cada árvore, retiraram-se discos de aproximadamente 5 cm de espessura, extraídos a 0,05 m do solo, que foram utilizados para determinação radial da densidade pelo método de atenuação da radiação gama e comprimento dos traqueídeos. Os resultados da análise de regressão linear indicaram que o lenho juvenil está limitado aos sete primeiros anos de crescimento da árvore e o lenho adulto é formado após os 20 anos de idade. No lenho adulto há diferenças significativas entre as idades médias obtidas através do comprimento dos traqueídeos e da densidade da madeira.

  2. Métodos de delimitação dos lenhos juvenil e adulto de três folhosas e propriedades biométricas de suas fibras

    Directory of Open Access Journals (Sweden)

    Rafael de Avila Delucis

    2014-10-01

    Full Text Available Diante da importância do conhecimento das respectivas regiões do lenho juvenil e adulto para a indústria de base madeireira, este estudo foi realizado com o objetivo de delimitar, por meio das metodologias de retas de regressão e do incremento anual, as regiões dos lenhos juvenil e adulto das madeiras de açoitacavalo, nogueira-pecã e plátano. O parâmetro anatômico utilizado nas delimitações foi o comprimento de fibra. Adicionalmente, foram medidas outras propriedades anatômicas: diâmetro de fibra, diâmetro de lume e espessura de fibra. As propriedades das fibras foram descritas estatisticamente em razão da diferenciação entre os lenhos proposta em cada metodologia, a fim de comparação. Conforme os métodos das retas de regressão e do incremento anual, as idades de segregação entre os lenhos foram de 21 e 19 anos para a madeira de açoitacavalo e 16 e 14 anos para a madeira de nogueira-pecã. Para a madeira de plátano, ambas as metodologias definiram que o lenho segregou com 14 anos. Pode-se verificar que não houve distinção entre os resultados obtidos com as duas metodologias de delimitação dos lenhos juvenil e adulto, exceto quanto ao comprimento de fibras do lenho juvenil. O método do incremento anual foi considerado preferencial, em razão da fonte de erro verificada no método das retas de regressão.

  3. Moles (Nevi)

    Science.gov (United States)

    ... resources Meet our partners Español Donate Diseases and treatments Acne and rosacea Bumps and growths Color problems Contagious skin diseases ... growths Moles public SPOT Skin Cancer™ Diseases and treatments Acne and rosacea Bumps and growths Keratosis pilaris Moles Seborrheic keratoses ...

  4. Mole Mapping.

    Science.gov (United States)

    Crippen, Kent J.; Curtright, Robert D.; Brooks, David W.

    2000-01-01

    The abstract nature of the mole and its applications to problem solving make learning the concept difficult for students, and teaching the concept challenging for teachers. Presents activities that use concept maps and graphing calculators as tools for solving mole problems. (ASK)

  5. The mole

    CERN Multimedia

    1974-01-01

    The mole continued its way around the SPS ring ... and on 31 July emerged where it started from, having completed its 7 kilometre journey without ever veering more than a couple of centimetres from its schedule path.

  6. Delimitação entre os lenhos juvenil e adulto de Pinus elliottii engelm Delimitation the juvenile and mature wood of Pinus elliottii engelm

    Directory of Open Access Journals (Sweden)

    Gilmara Pires de Moura Palermo

    2013-02-01

    Full Text Available Durante o crescimento, as árvores produzem diferentes tipos de tecido lenhoso. O xilema produzido nos primeiros anos até certa idade cambial é denominado lenho juvenil e apresenta propriedades físicas, mecânicas, químicas e anatômicas diferentes do xilema produzido após certa idade cambial, isto é, quando as células do câmbio já amadureceram. Dessa forma, um prévio conhecimento sobre a qualidade da matéria-prima produzida é de fundamental importância para melhor aplicabilidade do material. Com base nesse contexto, este trabalho objetivou, a partir de dados de comprimento de traqueídeos e densidade da madeira, delimitar a idade de transição entre os lenhos juvenil e adulto. Para isso, coletaram-se três árvores de Pinus elliottii var. elliottii Engelm., com 35 anos de idade, provenientes da Estação Experimental de Itapetininga, localizada em São Paulo, Brasil. De cada árvore, retiraram-se discos de aproximadamente 5 cm de espessura, extraídos a 0,05 m do solo, que foram utilizados para determinação radial da densidade pelo método de atenuação da radiação gama e comprimento dos traqueídeos. Os resultados da análise de regressão linear indicaram que o lenho juvenil está limitado aos sete primeiros anos de crescimento da árvore e o lenho adulto é formado após os 20 anos de idade. No lenho adulto há diferenças significativas entre as idades médias obtidas através do comprimento dos traqueídeos e da densidade da madeira.Trees produce different types of woody tissue during growth. The xylem produced in the first years until a certain cambial age is called juvenile wood and has different physical, mechanical, chemical and anatomical characteristics from that produced later, when the cambial cells have matured. Thus, prior knowledge of the quality of the wood is of fundamental importance for choosing the best use of the material. This work aimed at using data from length of the tracheid and wood density to

  7. Anatomia do lenho de Raulinoa echinata R.S.Cowan (Rutaceae uma espécie endêmica. Wood anatomy of Raulinoa echinata R.S.Cowan (Rutaceae an endemic species.

    Directory of Open Access Journals (Sweden)

    Adriano Antonio DAROSCI

    2012-12-01

    Full Text Available A anatomia vegetal é útil para a caracterização das espécies e do ambiente em que estas vivem. Muitas espécies respondem a algumas características ambientais com alterações na anatomia do lenho, por exemplo, na quantidade de vasos e raios, o que contribui para a sobrevivência no ambiente. Outras respostas anatômicas do lenho, devido às condições fisiológicas-estruturais presentes em diferentes regiões do caule, também são comuns. O presente estudo analisou a anatomia do lenho de Raulinoa echinata, espécie endêmica da mata ciliar do Vale do Itajaí, a fim de buscar alterações do lenho em resposta a algumas características ambientais, além daquelas provocadas pelas diferentes regiões do caule. Para tanto, amostras do lenho foram coletadas em duas regiões: próxima do solo e à altura do peito (1,30 m. Possíveis respostas de R. echinata ao ambiente ripário foram observadas no comprimento e na frequência das fibras, na largura dos raios e no comprimento e na frequência total de vasos, com diferenças significativas, entre as duas regiões, apenas em características quantitativas. A espécie apresentou, ainda, vasos múltiplos tangenciais e em cacho, características até então não descritas para Rutaceae. Não foram vistos na espécie canais traumáticos, característica comum para Rutaceae. Plant anatomy is useful for the characterization of species and their associated environment. Many species, because of habitat features, can show anatomical alterations of wood that permit their survival in the environment, quantity of vessels and rays, for example. Other anatomical alterations caused by structural-physiological conditions present in different regions of the stem are also common. In this study, the anatomy of Raulinoa echinata wood, an endemic riparian forest species of Itajaí Valley, was analyzed in order to identify alterations in wood because of specific habitat features, as well as adaptations in different

  8. Mole gun injury.

    Science.gov (United States)

    Pistré, V; Rezzouk, J

    2013-09-01

    A mole gun is a weapon, which is used to trap and kill moles. This report provides an overview of the state of knowledge of mole gun injuries, comparable to blast injuries caused by fireworks, explosive or gunshot. Over a 2-year period, the authors reported their experience with ten hand injuries caused by mole gun. Radial side of the hand was often concerned, particularly the thumb. The authors explain their choices in the management of such lesions. Surgery was performed primarily and a large debridement currently seemed to offer the best outcome for the patient. Blast, crush, burns and lacerations may explain the higher rate of amputation to the digits. A long period of physiotherapy, specifically of the hand, was needed before the patient could return to work. This ballistic hand trauma encountered by surgeons requires knowledge and understanding of these injuries. It should be in accordance with firearms law because of severe injuries encountered and possible lethal wounds.

  9. Atypical moles: diagnosis and management.

    Science.gov (United States)

    Perkins, Allen; Duffy, R Lamar

    2015-06-01

    Atypical moles are benign pigmented lesions. Although they are benign, they exhibit some of the clinical and histologic features of malignant melanoma. They are more common in fair-skinned individuals and in those with high sun exposure. Atypical moles are characterized by size of 6 mm or more at the greatest dimension, color variegation, border irregularity, and pebbled texture. They are associated with an increased risk of melanoma, warranting enhanced surveillance, especially in patients with more than 50 moles and a family history of melanoma. Because an individual lesion is unlikely to display malignant transformation, biopsy of all atypical moles is neither clinically beneficial nor cost-effective. The ABCDE (asymmetry, border irregularity, color unevenness, diameter of 6 mm or more, evolution) mnemonic is a valuable tool for clinicians and patients to identify lesions that could be melanoma. Also, according to the "ugly duckling" concept, benign moles tend to have a similar appearance, whereas an outlier with a different appearance is more likely to be undergoing malignant change. Atypical moles with changes suggestive of malignant melanoma should be biopsied, using an excisional method, if possible.

  10. Histamine combined with melphalan in isolated limb perfusion for the treatment of locally advanced soft tissue sarcomas: preclinical studies in rats Histamina combinada ao melfalano na perfusão de membro isolado para o tratamento de sarcomas de partes moles localmente avançado: estudos pré-clínicos em ratos

    Directory of Open Access Journals (Sweden)

    Flavia Brunstein

    2005-08-01

    Full Text Available PURPOSE: To evaluate the potential benefit of histamine combined with melphalan in the isolated limb perfusion (ILP as an alternative to TNF-alfa and melphalan combination, for the treatment of irressectable soft tissue sarcomas of the limbs in Brown Norway (BN rats. METHODS: 20 BN rats had small fragments of syngeneic BN-175 fibosarcoma inserted on the right hind limb. In 7-10 days the tumor reached a median diameter of 12-15 mm and they were randomly divided in four groups (sham, melphalan, histamine and escalating doses of histamine combined to melphalan being submitted to experimental ILP for 30 minutes. Tumors were measured daily with a caliper and the volume was calculated. RESULTS: Response curves showed a significant effect of the combination of histamine 200 mg/mL with melphalan, with 66% overall response, including 33% complete responses (pOBJETIVO: Avaliar o potencial benéfico da histamina combinada ao melfalano, na perfusão de membro isolado (PMI, como alternativa à combinação TNF-alfa mais melfalano, no tratamento de sarcomas de partes moles irressecaveis em extremidades, em ratos de linhagem Brown Norway (BN. MÉTODOS: 20 ratos BN foram submetidos a implantação de fragmentos de fibrosarcoma singênico BN-175 na pata traseira direita. Em cerca de 7-10 dias o tumor atingiu um diâmetro médio de 12-15 mm e foram aleatóriamente divididos em quatro grupos (controle, melfalano, histamina em doses progessivas combinada ao melfalano e histamina sendo submetidos a PMI experimental por 30 minutos. Os tumores foram então medidos diariamente com o uso de paquímetro e o volume tumoral calculado. RESULTADOS: As curvas de resposta mostram um efeito significativo da combinação de Histamina na concentração de 200 mg/mL ao melfalano, com 66% de resposta global incluindo 33% de respostas completas (p < 0.01. Não houve efeitos colaterais sistêmicos e localmente apenas edema leve e transitório nos animais tratados com histamine

  11. Goodbye, Father of the Mole

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Krtek, a snub-nosed, wide-eyed mole, has delighted cartoon lovers around the world for more than 50 years. Gently, cheerfully and almost always wordlessly, Krtek came to the aid of those in need and lamented the destruction of the environment.

  12. Of Bushwahckers, Termites and Moles.

    Science.gov (United States)

    Smelter, Richard W.

    2003-01-01

    Retired school administrator describes five types of school personnel that make an administrator's job difficult: Bushwackers, termites, CIA moles, rumor-mill addicts, and sartorial slobs. For example, termites are staff members who purposely volunteer for committees so they can sabotage the group's efforts from within. (PKP)

  13. Moles

    Science.gov (United States)

    ... Derm App Skin Facts Aging and Sun Damage Beauty Myths Preventing Sun Damage Skin Cancer Detection Skin ... done where cancer is a reasonable concern. Improving cosmetic appearance is another reason for excision, but all ...

  14. Podridão-do-lenho em plantios homogêneos de Acacia mangium Heartrot in homogeneous stands of Acacia mangium

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    Bernardo de Almeida Halfeld-Vieira

    2006-04-01

    Full Text Available O objetivo deste trabalho foi relatar a ocorrência da podridão-do-lenho em plantios homogêneos de Acacia mangium no Estado de Roraima. A observação dos sintomas iniciais em ferimentos de poda indica que a desrama artificial é um fator de predisposição. Estimativas realizadas em dois talhões comerciais constataram cerca de 8 e 39% de incidência da doença em árvores de três anos. Isolamentos a partir de árvores sintomáticas e testes de patogenicidade demonstram que Lasiodiplodia theobromae pode contribuir no processo de podridão. Este é o primeiro relato da podridão-do-lenho em A. mangium no Brasil, o que pode limitar sua exploração comercial.The objective of this work was to report the occurrence of heartrot in homogeneous stands of Acacia mangium in the State of Roraima, Brazil. Observations of symptoms initiating from pruning wounds indicated that the artificial pruning is a predisposing factor. A survey carried out in two commercial stands showed 8 and 39% of disease incidence in three-year-old trees. Isolations performed from symptomatic trees and pathogenicity tests demonstrated that the fungus Lasiodiplodia theobromae can incite the rot development. This is the first record of A. mangium heartrot in Brazil. The disease can restrict its commercial exploration.

  15. Tool to Distinguish Moles from Melanoma

    Science.gov (United States)

    Moles to Melanoma: Recognizing the ABCDE Features” presents photos that show changes in individual pigmented lesions over time, and describes the different appearances of moles, dysplastic nevi, and melanomas.

  16. Developing an Intuitive Approach to Moles.

    Science.gov (United States)

    Wakeley, Dawn M.; de Grys, Hans

    2000-01-01

    Explains the concept of mole and presents a teaching approach in which students can experiment with atoms and develop an understanding of mass ratios. Presents 10 examples of chemistry problems involving moles and unit conversations. (YDS)

  17. Little Czech Mole,Deep Affection From

    Institute of Scientific and Technical Information of China (English)

    Yang Wei; Guo Yan

    2007-01-01

    @@ Do you remember the little animated character in The Mole? The famous mole has lived for over 86 years in this animation movie which was made by Studio Bratri vtriku,Czech.When I was still a child,I was a crazy fan of this kind-hearted but a little silly mole.

  18. Invasive mole presenting as pain abdomen

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    Swati Singh

    2013-06-01

    Full Text Available Gestational trophoblastic neoplasms (GTN are proliferative as well as degenerative disorders of placental elements and include complete or partial mole (90%, invasive mole (5.8%, choriocarcinoma (1-2% and placental site tumor (1-2%. 15% of complete mole can develop into invasive mole. Very rarely (2-4% partial mole can develop into invasive one presenting with features of incomplete abortion, mixed abortion and sometimes as obstetric emergencies like intraperitoneal hemorrhage. So, proper diagnosis and timely intervention can prevent mortality and reduce the morbidity of the patients. [Int J Reprod Contracept Obstet Gynecol 2013; 2(3.000: 480-481

  19. Mold, Mould, Mole-d: The Three M's of Career Development

    Science.gov (United States)

    Amundson, Norman E.

    2008-01-01

    The author explores a creative idea development process wherein one begins by applying the image of "breaking the mold" to career development and then extending the process further by considering other related images. In this article, the related images include synonyms for mold such as mould and mole-d (the mole is a small burrowing animal with…

  20. Moles and Mole Control on British Farms, Amenities and Gardens after Strychnine Withdrawal

    Science.gov (United States)

    Baker, Sandra E.; Ellwood, Stephen A.; Johnson, Paul J.; Macdonald, David W.

    2016-01-01

    Simple Summary Moles are burrowing mammals that are regarded as pests in Britain, and until 2006 they could legally be killed using strychnine poison. When strychnine was withdrawn there were fears that mole populations would increase. We surveyed farmers, amenity managers and householders about moles and mole control on their land in 2007, post strychnine withdrawal. Kill-trapping was by far the preferred control method used and control may be used more than can be justified by damage levels or the effect of control on damage. Mole traps are unregulated, unlike most other spring traps, and some might not meet current welfare standards. We found no evidence that mole activity had increased since a 1992 survey of farms. Abstract Moles are considered pests in Britain, but this issue has been little studied. Lower welfare standards have been tolerated for moles than for most other managed wild mammal species, as use of both the controversial poison, strychnine, and unregulated traps have been permitted. Strychnine was withdrawn in 2006 and there were fears that mole populations would increase as a result. In 2007, we conducted a comprehensive, nationwide survey of land manager perceptions, opinions and behaviour regarding moles and mole control on farms, amenities and domestic gardens in Britain. We surveyed 2150 land managers (achieving a 59% response rate) and ground-truthed 29 responses. Moles were reported to be present on most farms and amenities, and 13% of gardens, and were more common in lighter soils. Where present, moles were usually considered pests, this being more likely in Wales, Scotland and northern England, on livestock and mixed farms, and on large, high-value amenities, e.g., racecourses and golf courses. Mole control followed similar patterns to mole presence. More control may occur than is economically, and therefore potentially ethically, justified. Control should be more carefully considered and, where necessary, more effectively targeted. Kill

  1. Caracterização e descrição da estrutura anatômica do lenho de seis espécies arbóreas com potencial medicinal Characterization and description of wood anatomical structure in six tree species with medicinal potential

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    G. Cury

    2011-01-01

    Full Text Available A caracterização morfoanatômica e a correta identificação das plantas medicinais são fundamentais para o controle de qualidade dos fitoterápicos. No presente trabalho é caracterizada a anatomia do lenho visando à identificação de seis espécies arbóreas com potencial medicinal. As amostras do lenho foram extraídas por método não destrutivo do tronco das árvores das espécies desenvolvidas em áreas de preservação. Em laboratório as amostras do lenho foram processadas para análises microscópicas do lenho, aplicando as metodologias para estudos de anatomia. Os resultados mostraram que o parênquima axial foi o parâmetro anatômico mais efetivo para a distinção das espécies através da análise do seu lenho. No trabalho discute-se a importância da aplicação da anatomia do lenho como ferramenta na identificação de espécies arbóreas medicinais.The morphoanatomical characterization and the correct identification of medicinal plants are fundamental for the quality control of phytotherapics. In the present work, wood anatomy was characterized in order to identify six tree species with medicinal potential. Wood samples were collected through a non-destructive method from the trunk of trees developed in conservation areas. In the laboratory, wood samples were processed for microscopic analysis by applying the methods for anatomical studies. Axial parenchyma was the most effective anatomical parameter to distinguish species through wood analysis. In this work, the importance of wood anatomy as a tool for the identification of medicinal tree species was discussed.

  2. Moles and Mole Control on British Farms, Amenities and Gardens after Strychnine Withdrawal.

    Science.gov (United States)

    Baker, Sandra E; Ellwood, Stephen A; Johnson, Paul J; Macdonald, David W

    2016-01-01

    Moles are considered pests in Britain, but this issue has been little studied. Lower welfare standards have been tolerated for moles than for most other managed wild mammal species, as use of both the controversial poison, strychnine, and unregulated traps have been permitted. Strychnine was withdrawn in 2006 and there were fears that mole populations would increase as a result. In 2007, we conducted a comprehensive, nationwide survey of land manager perceptions, opinions and behaviour regarding moles and mole control on farms, amenities and domestic gardens in Britain. We surveyed 2150 land managers (achieving a 59% response rate) and ground-truthed 29 responses. Moles were reported to be present on most farms and amenities, and 13% of gardens, and were more common in lighter soils. Where present, moles were usually considered pests, this being more likely in Wales, Scotland and northern England, on livestock and mixed farms, and on large, high-value amenities, e.g., racecourses and golf courses. Mole control followed similar patterns to mole presence. More control may occur than is economically, and therefore potentially ethically, justified. Control should be more carefully considered and, where necessary, more effectively targeted. Kill-trapping was the favoured recent and future method on farms and amenities, even if strychnine was to be reintroduced; however, because mole traps are currently unregulated, some might not meet current welfare standards if tested. We found no evidence for an increase in moles since a farm questionnaire survey conducted in 1992; this could have wider implications for future wildlife management policy changes. PMID:27338484

  3. Moles and Mole Control on British Farms, Amenities and Gardens after Strychnine Withdrawal.

    Science.gov (United States)

    Baker, Sandra E; Ellwood, Stephen A; Johnson, Paul J; Macdonald, David W

    2016-06-08

    Moles are considered pests in Britain, but this issue has been little studied. Lower welfare standards have been tolerated for moles than for most other managed wild mammal species, as use of both the controversial poison, strychnine, and unregulated traps have been permitted. Strychnine was withdrawn in 2006 and there were fears that mole populations would increase as a result. In 2007, we conducted a comprehensive, nationwide survey of land manager perceptions, opinions and behaviour regarding moles and mole control on farms, amenities and domestic gardens in Britain. We surveyed 2150 land managers (achieving a 59% response rate) and ground-truthed 29 responses. Moles were reported to be present on most farms and amenities, and 13% of gardens, and were more common in lighter soils. Where present, moles were usually considered pests, this being more likely in Wales, Scotland and northern England, on livestock and mixed farms, and on large, high-value amenities, e.g., racecourses and golf courses. Mole control followed similar patterns to mole presence. More control may occur than is economically, and therefore potentially ethically, justified. Control should be more carefully considered and, where necessary, more effectively targeted. Kill-trapping was the favoured recent and future method on farms and amenities, even if strychnine was to be reintroduced; however, because mole traps are currently unregulated, some might not meet current welfare standards if tested. We found no evidence for an increase in moles since a farm questionnaire survey conducted in 1992; this could have wider implications for future wildlife management policy changes.

  4. Magnetic orientation in the giant mole-rat and the silvery mole-rat

    OpenAIRE

    OLIVERIUSOVÁ, Ludmila

    2008-01-01

    The magnetic orientation was study in several species of rodents. Aim of this work was verify magnetic sense in two species of subterranean rodents: the giant mole-rat and the silvery mole-rat. A spontaneous directional preference in the magnetic field was tested in circular arena.

  5. Anatomia do lenho de Uncaria guianensis e U. tomentosa (Rubiaceae do estado do Acre, Brasil Wood anatomy of Uncaria guianensis e U. tomentosa (Rubiaceae from the State of Acre, Brazil

    Directory of Open Access Journals (Sweden)

    Percy A. Zevallos Pollito

    2006-01-01

    Full Text Available As plantas de Uncaria guianensis e U. tomentosa são lianas trepadeiras, arbustos trepadores ou rasteiros ascendentes que ocorrem em amplas áreas da Amazônia brasileira e países da América Central e do Sul. Possuem excepcional importância medicinal, com sua casca, lenho e folhas utilizadas pelos povos amazônicos e pela indústria farmacêutica. Face a necessidade da identificação das plantas em condições de campo e de laboratório, o presente trabalho descreveu a estrutura anatômica do lenho de Uncaria guianensis e U. tomentosa, ocorrentes no Estado do Acre, Brasil. Os resultados mostraram que o lenho das espécies é característico da família Rubiaceae, a exceção dos vasos arredondados, grandes e solitários, parenquima axial difuso e largura dos raios que são próprios das lianas.Uncaria guianensis and U. tomentosa are climbing lianas, bush lianas occuring in large areas of Brazilian Amazon and Central and South America countries. The species presented exceptional medicinal importance, with its bark, wood and leaves used by Amazon native people and pharmaceutical industries. Considering the importance of the species identification in field and laboratory conditions, the present work described the anatomical structure of Uncaria guianensis and U. tomentosa, which occurs in State of Acre, Brazil. The results showed that the wood of the species was characteristic of the Rubiaceae family, except the rounded vessel, greater and solitary, parenchyma axial diffuse and width of the rays, proper of lianas.

  6. Invasive Mole Presenting as Acute Haemoperitoneum

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    Sunesh Kumar, N. Vimala, Suneeta Mittal

    2004-07-01

    Full Text Available We report a case of invasive hydatidiform mole presenting as an acute primary haemoperitoneum.The patient presented with acute abdominal pain and signs of haemoperitoneum. Emergencylaparotomy revealed a molar pregnancy perforating through the uterine fundus, resulting in massivehaemoperitoneum. The serum beta chorionic gonado-tropin (ß-hCG levels regressed spontaneouslyfollowing evacuation of the molar pregnancy.

  7. Ossicular density in golden moles (Chrysochloridae).

    Science.gov (United States)

    Mason, Matthew J; Lucas, Sarah J; Wise, Erica R; Stein, Robin S; Duer, Melinda J

    2006-12-01

    The densities of middle ear ossicles of golden moles (family Chrysochloridae, order Afrosoricida) were measured using the buoyancy method. The internal structure of the malleus was examined by high-resolution computed tomography, and solid-state NMR was used to determine relative phosphorus content. The malleus density of the desert golden mole Eremitalpa granti (2.44 g/cm3) was found to be higher than that reported in the literature for any other terrestrial mammal, whereas the ossicles of other golden mole species are not unusually dense. The increased density in Eremitalpa mallei is apparently related both to a relative paucity of internal vascularization and to a high level of mineralization. This high density is expected to augment inertial bone conduction, used for the detection of seismic vibrations, while limiting the skull modifications needed to accommodate the disproportionately large malleus. The mallei of the two subspecies of E. granti, E. g. granti and E. g. namibensis, were found to differ considerably from one another in both size and shape. PMID:16944164

  8. PARTIAL HYDATIDIFORM MOLE WITH A LIVE FETUS: A RARE ENTITY

    Directory of Open Access Journals (Sweden)

    Mounika Reddy

    2015-07-01

    Full Text Available BACKGROUND : Gestational trophoblastic neoplasia (GTN represents a spectrum of premalignant and malignant diseases that occur after abnormal fertilization. [ 1 ] GTN includes complete hydatidiform mole (CHM, partial hydatidiform mole (PHM, invasive mole, choriocarcinoma, and placental - site trophoblastic tumor (PSTT. CHM and PHM together account for 80% of all cases of GTN.

  9. Insights: A LAP on Moles: Teaching an Important Concept.

    Science.gov (United States)

    Ihde, John

    1985-01-01

    Describes a learning activity packet (LAP) designed to help students understand the basic concept of the mole as a chemical unit; know relationships between the mole and atomic weights in the periodic table; and solve basic conversion problems involving moles, atoms, and molecules. (JN)

  10. Prevalence of Toxoplasma gondii in common moles (Talpa europaea)

    NARCIS (Netherlands)

    Krijger, I.M.; Cornelissen, J.B.W.J.; Wisselink, H.J.; Meerburg, B.G.

    2014-01-01

    Background The prevalence of Toxoplasma gondii in common moles, Talpa europaea, was investigated in order to determine whether moles can serve as an indicator species for T. gondii infections in livestock. Findings In total, 86 moles were caught from 25 different sites in the Netherlands. Five diffe

  11. Invasive mole: a rare cause of postmenopausal bleeding

    Directory of Open Access Journals (Sweden)

    Mamour Guèye

    2013-06-01

    Full Text Available Gestational trophoblastic disease (GTD describes a number of gynaecological tumours that originate in the trophoblast layer, including hydatidiform mole (complete or partial, placental site trophoblastic tumour, choriocarcinoma and invasive mole. Invasive moles are responsible of most cases of localized gestational trophoblastic neoplasia (GTN. Invasive mole is a condition where a molar pregnancy, such as a partial hydatidiform mole or complete hydatidiform mole, invades the wall of the uterus. It is an extremely rare condition. As GTN is not considered in the differential diagnosis of postmenopausal uterine malignancies, its preoperative diagnosis is challenging. We report a case of invasive hydatidiform mole in a postmenopausal woman discovered in a context of postmenopausal bleeding. She underwent hysterectomy and followed up till her beta hCG levels were within normal limits. The patient is in complete remission in the first postoperative year. [Int J Reprod Contracept Obstet Gynecol 2013; 2(3.000: 451-453

  12. Ultrasonographic findings of hydatidiform mole and missed abortion

    International Nuclear Information System (INIS)

    To establish the sonographic characteristics of the hydatidiform mole and the missed abortion with placental degeneration, we have retrospectively analyzed 12 cases of complete mole, 10 cases of partial mole, and 10 cases of missed abortion with placental hydropic degeneration, collected at Taegu Catholic General Hospital, from January 1986 to December 1989. The results were as follows : 1. Of 12 cases of complete mole, all demonstrated diffuse intrauterine vesicular pattern of internal echo without a gestational sac. Two cases were recurred after D and E. 2. The partial mole was characterized by focal (70%) or diffuse (20%) distribution of hydatidiform placental change and a gestational sac (100%) with or without a macerated fetus. But the striking hydatidiform placental change was not present in one cases of partial mole. 3. The uterus was larger for dates in 9 cases (90%) of complete mole, but smaller for dates in 7 cases (70%) of partial mole. 4. The missed abortion with placental hydropic degeneration was indistinguished from a partial mole due to their similar sonographic appearance : focal or diffuse cystic change of a placenta, a distorted gestational sac with or without a fetus, and a smaller uterus for dates. On conclusion, the complete mole could be easily distinguished from a partial mole or a missed abortion by sonography : a gestational sac or an area of noncystic placenta was not identified in a complete mole. The partial mole was indistinguished from a missed abortion, but if there is the suspicion of trophoblastic proliferation, such as a convex placental surface or a larger uterus for dates, then the diagnosis is probably a partial mole rather than a missed abortion

  13. Localized vibrations: moles in structure-land

    Science.gov (United States)

    van der Maas, John H.

    1992-03-01

    Functional groups reveal specific information about their direct surroundings; in fact, they form the moles, the undercover agents, in molecules. However, as with agents, the information is produced in coded form (spectral data) so one has to know the code in detail before the message is completely understood. The substantially improved accuracy (wavenumber, intensity) and sensitivity brought about by FT-instruments, in combination with computer software, offer extended spectral information. Functional groups can now be examined in great detail. Obviously the amount of deducible structural items is group dependent, implying that one has to pursue the probing qualities of a functionality prior to use. The OH-group, and more in particular the OH-stretching vibration, proves to be an extremely good mole. Its potentials are demonstrated on conformational studies of various saturated alcohols, the presence of OH(DOT)(DOT)(DOT)(pi) bridges, the strength and type of OH(DOT)(DOT)(DOT)O bridges, all in an apolar solvent, and on the disclosure of different hydrogen bonds in some solid samples.

  14. Estudo da atividade hipoglicemiante do chá do lenho da Quássia-do-Brasil, Picrasma crenata (Vell. Engl. em camundongos e ratos | Study of the hypoglicemic activity of the tea of the wood of Quassia-do-Brasil, Picrasma crenata (Vell. Engl. in mice and rats

    Directory of Open Access Journals (Sweden)

    Ana Luisa Quadros dos Santos Mauro

    2015-02-01

    Full Text Available A atividade hipoglicemiante do chá do lenho da Quássia-do-Brasil, Picrasma crenata (Vell. Engl.- Simaroubaceae, nas concentrações de 5, 10 e 20%, foi estudada pela determinação da glicemia em animais normoglicêmicos, nos quais a concentração a 10% apresentou uma resposta mais efetiva. Em animais tornados diabéticos pela administração intravenosa de estreptozotocina (65mg/kg e em animais hiperglicêmicos pela administração intravenosa de uma sobrecarga de glicose a 25%, esta mesma concentração do chá também promoveu uma diminuição nos níveis glicêmicos. Tanto nos animais normo como nos hiperglicêmicos, o propranolol (10mg/kg, intraperitoneal, um β-bloqueador adrenérgico nãoseletivo, não influenciou na atividade hipoglicemiante do chá. O chá de Quássia-do-Brasil foi capaz de inibir a absorção intestinal de glicose, e também a sua reabsorção ao nível do glomérulo renal. O mecanismo hipoglicemiante do chá parece não estar envolvido com o aumento da secreção de insulina. --------------------------------------------------------------------------------------------- The hypoglycemic activity of tea made from the wood of Quássia-do-Brasil [Picrasma crenata (Vell. Engl.] was studied by assessment of glycemia in normoglycemic animals. The tea was given in concentrations of 5%, 10%, and 20%, with the concentration of 10% proving to be most effective. The 10% concentration promoted a decrease of glycemic levels in diabetic animals who were given streptozotocin (65 mg/kg and in hyperglycemic animals who received an overloading glucose solution of 25% via intravenous administration Propranolol (10 mg/kg, intraperitoneal, a non-specific adrenergic β-blocker, did not affect the activity of the tea in normal or hyperglycemic animals. The tea of Quássia-do-Brasil was able to inhibit intestinal absorption of glucose as well as its reabsorption from the renal glomerulus. The hypoglycemic mechanism of the tea does not

  15. ABO Genotyping of Complete Hydatidiform Moles

    Directory of Open Access Journals (Sweden)

    R. A. Fisher

    1993-01-01

    Full Text Available It has been suggested that the ABO blood group of a patient and her partner influence the clinical outcome for patients having a pregnancy with a complete hydatidiform mole (CHM. Since CHM lack red blood Cells, it has not previously been possible to type CHM serologically and investigate the relationship between the blood group of the CHM and that of the patient. In the present study we have demonstrated the feasibility of using molecular genotyping to determine the ABO genotype of CHM, the ABO genotype being consistent with the androgenetic origin of CHM in all cases. In the series of 48 cases of CHM, the requirement for chemotherapy was not significantly different in those patients with a CHM of like blood group compared with those with a CHM of unlike blood group.

  16. MOLES3: Implementing an ISO standards driven data catalogue

    Directory of Open Access Journals (Sweden)

    Graham A Parton

    2015-02-01

    Full Text Available ISO19156 Observations and Measurements (O&M provides a standardised framework for organising information about the collection of information about the environment.  Here we describe the implementation of a specialisation of O&M for environmental data, the Metadata Objects for Linking Environmental Sciences (MOLES3.MOLES3 provides support for organising information about data, and for user navigation around data holdings. The implementation described here, “CEDA-MOLES”, also supports data management functions for the Centre for Environmental Data Archival, CEDA. The previous iteration of MOLES (MOLES2 saw active use over five years, being replaced by CEDA-MOLES in late 2014. During that period important lessons were learnt both about the information needed, as well as how to design and maintain the necessary information systems. In this paper we review the problems encountered in MOLES2; how and why CEDA-MOLES was developed and engineered; the migration of information holdings from MOLES2 to CEDA-MOLES; and, finally, provide an early assessment of MOLES3 (as implemented in CEDA-MOLES and its limitations.Key drivers for the MOLES3 development included the necessity for improved data provenance, for further structured information to support ISO19115 discovery metadata  export (for EU INSPIRE compliance, and to provide appropriate fixed landing pages for Digital Object Identifiers (DOIs in the presence of evolving datasets. Key lessons learned included the importance of minimising information structure in free text fields, and the necessity to support as much agility in the information infrastructure as possible without compromising on maintainability both by those using the systems internally and externally (e.g. citing in to the information infrastructure, and those responsible for the systems themselves. The migration itself needed to ensure continuity of service and traceability of archived assets.

  17. Moles: Tool-Assisted Environment Isolation with Closures

    Science.gov (United States)

    de Halleux, Jonathan; Tillmann, Nikolai

    Isolating test cases from environment dependencies is often desirable, as it increases test reliability and reduces test execution time. However, code that calls non-virtual methods or consumes sealed classes is often impossible to test in isolation. Moles is a new lightweight framework which addresses this problem. For any .NET method, Moles allows test-code to provide alternative implementations, given as .NET delegates, for which C# provides very concise syntax while capturing local variables in a closure object. Using code instrumentation, the Moles framework will redirect calls to provided delegates instead of the original methods. The Moles framework is designed to work together with the dynamic symbolic execution tool Pex to enable automated test generation. In a case study, testing code programmed against the Microsoft SharePoint Foundation API, we achieved full code coverage while running tests in isolation without an actual SharePoint server. The Moles framework integrates with .NET and Visual Studio.

  18. Kinematics of Terrestrial Locomotion in Mole Cricket Gryllotalpa orientalis

    Institute of Scientific and Technical Information of China (English)

    Yan Zhang; He Huang; Xiangyang Liu; Luquan Ren

    2011-01-01

    The fore leg of mole cricket (Orthoptera: Gryllotalpidae) has developed into claw for digging and excavating. As the result of having a well-suited body and appendages for living underground, mole cricket still needs to manoeuvre on land in some cases with some kinds of gait. In this paper, the three-dimensional kinematics information of mole cricket in terrestrial walking was recorded by using a high speed 3D video recording system. The mode and the gait of the terrestrial walking mole cricket were investigated by analyzing the kinematics parameters, and the kinematics coupling disciplines of each limb and body were discussed. The results show that the locomotion gait of mole cricket in terrestrial walking belongs to a distinctive alternating tripod gait. We also found that the fore legs of a mole cricket are not as effective as that ofcommon hexapod insects, its middle legs and body joints act more effective in walking and turning which compensate the function of fore legs. The terrestrial locomotion of mole cricket is the result of biological coupling of three pairs of legs, the distinctive alternating tripod gait and the trunk locomotion.

  19. Brain mass and cranial nerve size in shrews and moles.

    Science.gov (United States)

    Leitch, Duncan B; Sarko, Diana K; Catania, Kenneth C

    2014-09-01

    We investigated the relationship between body size, brain size, and fibers in selected cranial nerves in shrews and moles. Species include tiny masked shrews (S. cinereus) weighing only a few grams and much larger mole species weighing up to 90 grams. It also includes closely related species with very different sensory specializations - such as the star-nosed mole and the common, eastern mole. We found that moles and shrews have tiny optic nerves with fiber counts not correlated with body or brain size. Auditory nerves were similarly small but increased in fiber number with increasing brain and body size. Trigeminal nerve number was by far the largest and also increased with increasing brain and body size. The star-nosed mole was an outlier, with more than twice the number of trigeminal nerve fibers than any other species. Despite this hypertrophied cranial nerve, star-nosed mole brains were not larger than predicted from body size, suggesting that magnification of their somatosensory systems does not result in greater overall CNS size.

  20. Results of the mole penetration tests in different materials

    Science.gov (United States)

    Wawrzaszek, Roman; Seweryn, Karol; Grygorczuk, Jerzy; Banaszkiewicz, Marek; Rybus, Tomasz; Wisniewski, Lukasz; Neal, Clive R.; Huang, Shaopeng

    2010-05-01

    Mole devices are low velocity, medium to high energy, self-driven penetrators, designed as a carrier of different sensors for in situ investigations of subsurface layers of planetary bodies. The maximum insertion depth of such devices is limited by energy of single mole's stroke and soil resistance for the dynamic penetration. A mole penetrator ‘KRET' has been designed, developed, and successfully tested at Space Research Centre PAS in Poland. The principle of operation of the mole bases on the interaction between three masses: the cylindrical casing, the hammer, and the rest of the mass, acting as a support mass. This approach takes advantage of the MUPUS penetrator (a payload of Philae lander on Rosetta mission) insertion tests knowledge. Main parameters of the mole KRET are listed below: - outer diameter: 20.4mm, - length: 330mm, - total mass: 488g, - energy of the driving spring: 2.2J, - average power consumption: 0.28W, - average insertion progress/stroke: 8.5mm, The present works of Space Research Center PAS team are focused on three different activities. First one includes investigations of the mole penetration effectiveness in the lunar analogues (supported by ESA PECS project). Second activity, supported by Polish national fund, is connected with numerical calculation of the heat flow investigations and designing and developing the Heat Flow Probe Hardware Component (HPHC) for L-GIP NASA project. It's worth noting that L-GIP project refers to ILN activity. Last activity focuses on preparing the second version of the mole ready to work in low thermal and pressure conditions. Progress of a mole penetrator in granular medium depends on the mechanical properties of this medium. The mole penetrator ‘KRET' was tested in different materials: dry quartz sand (0.3 - 0.8 grain size), wet quartz sand, wheat flour and lunar regolith mechanical simulant - Chemically Enhanced OB-1 (CHENOBI). Wheat flour was selected due to its high cohesion rate and small grain size

  1. Magnetic compass orientation in the blind mole rat Spalax ehrenbergi.

    Science.gov (United States)

    Kimchi, T; Terkel, J

    2001-02-01

    The blind mole rat Spalax ehrenbergi is a solitary, subterranean rodent that digs and inhabits a system of branching tunnels, with no above-ground exits, which it never leaves unless forced to. To survive, the mole rat must be able to orient efficiently in its tunnel system. The sensory channels available for spatial orientation in the subterranean environment are restricted in comparison with those existing above ground. This study examined the possibility that the mole rat is able to perceive and use the earth's magnetic field to orient in space. Experiments were performed using a device constructed from a pair of electromagnetic 'Helmholtz coils', which create a magnetic field whose direction and strength can be altered. In the first experiment, we tested a group of mole rats (N=33) in an eight-armed maze under the earth's natural magnetic field to determine whether they have directional preferences for the location of their sleeping nest, food chamber and toilet site. A second group of mole rats (N=30) was tested for their directional preference after the earth's magnetic field had been experimentally shifted by 180 degrees. We found that the first group exhibited a significant preference (Pbuild both their sleeping nest and their food store in the southern sector of the maze, whereas the second group shifted the location of their nests (Pbirds, magnetic compass orientation in the mole rat is independent of light stimulation. In the third experiment, we examined whether mole rats (N=24) use the earth's magnetic field as a compass cue to orient in a labyrinth. In the first stage (trials 1-13), the animals were trained to reach a goal box at the end of a complex labyrinth until all individuals had learned the task. In the second stage (trial 14), half the trained mole rats underwent another labyrinth trial under the earth's natural magnetic field, while the other half were tested under a magnetic field shifted by 180 degrees. We found a significant decrease (P<0

  2. Genetic variants of Cao Bang hantavirus in the Chinese mole shrew (Anourosorex squamipes) and Taiwanese mole shrew (Anourosorex yamashinai).

    Science.gov (United States)

    Gu, Se Hun; Arai, Satoru; Yu, Hon-Tsen; Lim, Burton K; Kang, Hae Ji; Yanagihara, Richard

    2016-06-01

    To determine the genetic diversity and geographic distribution of Cao Bang virus (CBNV) and to ascertain the existence of CBNV-related hantaviruses, natural history collections of archival tissues from Chinese mole shrews (Anourosorex squamipes) and Taiwanese mole shrews (Anourosorex yamashinai), captured in Guizho Province, People's Republic of China, and in Nantou County, Taiwan, in 2006 and 1989, respectively, were analyzed for hantavirus RNA by RT-PCR. Pair-wise alignment and comparison of the S-, M- and L-segment sequences indicated CBNV in two of five Chinese mole shrews and a previously unrecognized hantavirus, named Xinyi virus (XYIV), in seven of 15 Taiwanese mole shrews. XYIV was closely related to CBNV in Vietnam and China, as well as to Lianghe virus (LHEV), recently reported as a distinct hantavirus species in Chinese mole shrews from Yunnan Province in China. Phylogenetic analyses, using maximum-likelihood and Bayesian methods, showed that XYIV shared a common ancestry with CBNV and LHEV, in keeping with the evolutionary relationship between Anourosorex mole shrews. Until such time that tissue culture isolates of CBNV, LHEV and XYIV can be fully analyzed, XYIV and LHEV should be regarded as genetic variants, or genotypes, of CBNV. PMID:26921799

  3. Mola hidatiforme e doença trofoblástica gestacional Hydatidiform mole and gestational trophoblastic disease

    Directory of Open Access Journals (Sweden)

    Jurandyr Moreira de Andrade

    2009-02-01

    Full Text Available A mola hidatiforme é uma complicação relativamente infrequente da gravidez, mas com potencial para evolução para formas que necessitam de tratamento sistêmico e podem ser ameaçadoras da vida. Sob a denominação de mola hidatiforme há duas entidades histopatológicas e clínicas: a mola parcial e a completa. As diferenças entre estas duas formas são importantes, devido ao risco de evolução para formas persistentes, ou seja, mais alto para as completas. O diagnóstico da mola hidatiforme, seu tratamento e seguimento após o tratamento inicial sofreram alterações importantes nos últimos anos. O número de pacientes assintomáticas tem aumentado devido ao emprego de ultrassonografia no início da gravidez. Para a resolução da mola hidatiforme é necessário evitar o emprego de medicamentos que induzam contrações uterinas e usar a vácuo-aspiração. Deve ser prescrito o método contraceptivo hormonal logo após o esvaziamento da mola. O seguimento é baseado nas dosagens seriadas semanais de gonadotrofinas coriônicas. É importante que o método empregado detecte todas as formas das gonadotrofinas coriônicas (molécula intacta, hiperglicosilada, subunidade β livre e fragmento central da subunidade β.The hydatiform mole is a relatively rare pregnancy complication, but with potential to evolve to forms which need systemic treatment and can be a threat to life. There are two histopathological and clinical entities under the name of hydatiform mole: the partial and the complete mole. The differences between the two forms are important due to risk of evolution to persistent forms, which is higher for the complete moles. The diagnosis, treatment and follow-up of hydatiform mole have been under important changes in the last years. The number of asymptomatic patients has increased, due to the use of ultrasonography at the onset of pregnancy. The use of medication that induces uterine contractions must be avoided, and vacuum

  4. Ultrasonographic findings of Myoma, H-mole and Missed abortion

    International Nuclear Information System (INIS)

    Ultrasonography is very important in the diagnosis of various kinds of diseases in Obsterics and Gynecology. It has high diagnostic accuracy in the diagnosis of pelvic masses and widely used for the detection of normal orpathologic pregnancy. But still it is difficult to differentiate degenerated myoma, H-mole and missed abortion by ultrasonography. So the authors analyzed the ultrasonographic findings of 81 patients with myoma(29 cases), H-mole(23 cases), and missed abortion(29 cases) and the results are as follows; 1. Diagnostic accuracy was 8.6% in myoma, 87% in H-mole and 89% in missed abortion. 2. The most typical ultrasonographic finding of myoma was obulated mass contour with nonhomogenous internal echo. 3. The most characteristic finding of H-mole was fine vesicular pattern internal echo with globular enlargement of uterus. 4. The most frequent finding of missed abortion was deformed gestational sac with or without remained fetal echo. 5. Clinical correlation was very important for accurate diagnosis, especially when differential diagnosis was very difficult between myoma with marked cystic degeneration, missed abortion with large distorted gestational sac and H-mole with severe degeneration

  5. Epidemiological Factors and Pathomorphologic Characteristics of Hydatidiform Mole

    Directory of Open Access Journals (Sweden)

    Lejla Muminhodžić

    2013-09-01

    Full Text Available Introduction: Hydatidiform mole is a gestational trophoblastic disease characterized by a range of disorders of abnormal trophoblastic proliferation.Methods: This was a retrospective study of 70 singletone pregnancies until the 12th week of gestational age diagnosed with hydatidiform mole or spontaneously aborted physiological pregnancy. The pregnantwomen had almost similar demographic features and were divided into two groups. 35 pregnant women with a molar pregnancy were included in the study group; while 35 pregnant women with physiologicalpregnancy spontaneously aborted were included in the control group. Analyzed parameters included a pregnant woman’s age, blood type, parity and previous pregnancies (course and outcomes.Results: In the study group 11.43% of cases had hydatidiform mola during previous pregnancies as well as the advanced average gestational age of an ongoing pregnancy (9.63±1.83 in contrast to 8.25±2.03in the control group. The pregnant women with the hydatidiform mole were reported to have statistically significantly greater number of irregular villous borders (71.43%; slightly enlarged villi (54.29%; moderatedpresence of cisterns (65.71% as well as mild avascularisation of villi (57.14%.Conclusion: It was concluded that a previous molar pregnancy represents the highest risk for hydtidiforme mole and the pathomorphologic analysis of vilous changes can be a reliable parameter for establishingproper diagnosis of partial hydatidiform mole.

  6. Twin pregnancy with a complete hydatidiform mole and coexisting foetus

    Directory of Open Access Journals (Sweden)

    C. N. Sheela

    2016-08-01

    Full Text Available Coexistence of a viable foetus with a complete hydatidiform mole is a rare entity. Traditionally, termination of pregnancy was recommended because of severe maternal and foetal complications. Here we report a case of a 30 year old G2A1 at 27 weeks with a twin pregnancy with a complete hydatidiform mole and coexisting normal foetus who took home a healthy baby without any persistent trophoblastic disease. This case is presented for the rarity of occurrence and good outcome. [Int J Reprod Contracept Obstet Gynecol 2016; 5(8.000: 2881-2883

  7. A history of mole crickets (Orthoptera: Gryllotalpidae) in Puerto Rico

    OpenAIRE

    Frank, J. Howard

    2009-01-01

    Published claims in 1887-1903 that the mole cricket Neocurtilla hexadactyla (Perty) occurs in Puerto Rico all seem to be derived from a misidentification made by Agustín Stahl, a medical practitioner and collector of natural history objects, published in 1882. That species does not seem now to occur in Puerto Rico and almost certainly never did. However, the opportunity still exists for it to colonize by wind-assisted flight from islands to the southeast just as we believe did the mole cricke...

  8. The mole, amount of substance and primary methods

    Science.gov (United States)

    Milton, Martin J. T.

    2013-04-01

    This paper is an introduction to the principles developed for the application of metrology to the field of chemistry and particularly to analytical chemistry. It starts with a discussion of the mole, the base unit of the SI that is most relevant to analytical chemistry. The mole has become the subject of particular discussion recently, since the publication of proposals to re-define it along with three other base units of the SI. This discussion has also generated interest in the origin of the term ‘amount of substance’ used as the quantity for which the mole is the unit. This paper reviews the origin of this term and explains why it is not sufficient to replace it with an alternative such as a ‘number of entities’. The paper concludes with some discussion of how the mole is realized through the use of primary methods of measurement. This paper is based on a lecture given at the International School of Physics ‘Enrico Fermi’, Course CLXXXV: Metrology and Physical Constants,held in Varenna on 17-27 July 2012. It will also be published in the proceedings of the school, edited by E Bava, M Kühne and A M Rossi (IOS Press, Amsterdam and SIF, Bologna).

  9. Placentation in the Hottentot golden mole, Amblysomus hottentotus (Afrosoricida: Chrysochloridae)

    DEFF Research Database (Denmark)

    Jones, C J P; Carter, A M; Bennett, N C;

    2009-01-01

    The placentation of the Hottentot golden mole (Amblysomus hottentotus) has been examined using light and electron microscopy and lectin histochemistry of nine specimens at both mid and late gestation. The placentae were lobulated towards the allantoic surface and the lobules contained roughly...

  10. AO operations at Gemini South

    Science.gov (United States)

    Marin, Eduardo; Cardwell, Andrew; Pessev, Peter

    2014-08-01

    The 8m Gemini South telescope is entering an exciting new era of AO operations, which put it at the forefront of astronomical AO in terms of both wide field AO, and extreme-AO systems. Major milestones achieved were the successful commissioning of GeMS, in 2012, and GPI, in late 2013 and early 2014. Currently we are operating two of the worlds most advanced astronomical AO systems. Gemini, running primarily in queue, must balance the promise of AO with the demands of the community to use non-AO instruments. We discuss the current state of the two AO systems, and their operational models. The preparations that go into planning each AO run, the difficulties in scheduling around non-AO instruments, and the differences between scheduling LGS AO and non-LGS AO are discussed.

  11. Linewidth Narrowing and Intensity Enhancement of Wavelength Tunable MOLEDs

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Microcavity structure consisting of distributed Bragg reflector and metal aluminum mirror is designed. Using tris (8-hydroxyquinoline) aluminum as electron-transport layer and emissive layer, and N, N′-bis (3-methylphenyl)-N, N′-diphenylbenzidine as a hole-transport layer, microcavity organic light-emitting diodes(MOLEDs) are fabricated. Compared to the electroluminescence spectra of non-cavity OLEDs, the linewidth of the MOLEDs is compressed from 75 nm to 7 nm, and the peak intensity enhances by a factor of about 3. When the effective length of the microcavity is modified, resonance wavelength can be selectively scanned over a very wide range of wavelengths that cover almost 140 nm.

  12. Unpacking the Meaning of the Mole Concept for Secondary School Teachers and Students

    Science.gov (United States)

    Fang, Su-Chi; Hart, Christina; Clarke, David

    2014-01-01

    The "mole" is a fundamental concept in quantitative chemistry, yet research has shown that the mole is one of the most perplexing concepts in the teaching and learning of chemistry. This paper provides a survey of the relevant literature, identifies the necessary components of a sound understanding of the mole concept, and unpacks and…

  13. Teaching the Mole Concept Using a Conceptual Change Method at College Level

    Science.gov (United States)

    Uce, Musa

    2009-01-01

    Chemistry is a subject area that is difficult to understand for some students as it contains abstract concepts, such as mole, molecule and particle. The mole concept is one of the most important topics in which students have difficulty in understanding. There are many studies in the literature on the mole concept. Students who do not fully…

  14. AO Psc time keeping

    Science.gov (United States)

    Bonnardeau, Michel

    2015-07-01

    Eleven seasons, from 2004 to 2014, of photometric monitoring of the intermediate polar AO Psc are presented and are compared with previous observations. The spin up of the white dwarf is found to be slowing down. The amplitudes of the modulated and non-modulated components of the brightness are found to have undergone a major change in 2007.

  15. Idade de segregação do lenho juvenil e adulto pela variação da massa específica de açoita-cavalo Estimating the age of demarcation of young and mature wood in açoita-cavalo

    Directory of Open Access Journals (Sweden)

    Matheus Lemos de Peres

    2012-09-01

    Full Text Available O presente trabalho teve como objetivo estimar a idade de segregação do lenho de Luehea divaricata Mart. (açoita-cavalo por meio da variação radial da massa específica. Para o desenvolvimento do estudo, foram coletadas dez árvores de duas regiões do Estado do Rio Grande do Sul. Foi retirado um disco por árvore, com aproximadamente 2cm de espessura a 0,10m de altura do tronco. De cada disco, retirou-se, com auxílio de uma serra-fita, uma bagueta central de 2,0cm de largura, bem orientada no sentido radial, incluindo a medula no centro, dividiu-se então a bagueta em duas amostras "A" e "B". A massa específica foi obtida da relação entre peso seco e volume úmido. O volume úmido foi determinado de acordo com a norma ASTM D 2395 - 93, 1995. A segregação dos lenhos foi encontrada por regressão linear simples dos dados de variação da massa específica no sentido medula-casca. Foi feita uma regressão linear na faixa crescente dos dados e outra na faixa decrescente. A intersecção das retas extrapoladas foi adotada como idade de segregação. Os resultados obtidos mostraram que o lenho de açoita-cavalo segrega em aproximadamente 26 anos para a região da Depressão Central e 23 anos para a região da Encosta Superior do Nordeste. Nos dados de variação de massa específica, foi feita uma análise de variância multifatorial. Constatou-se que há diferença significativa entre lenhos e entre regiões. Por outro lado, as amostras A e B de cada árvore não foram estatisticamente diferentes entre si.This study aims to estimate the age of segregation of young and mature wood of Luehea divaricata Mart., using the radial variation of specific gravity. To the development of this study were collected ten trees from two regions of the state of Rio Grande do Sul. Discs with thickness of 2cm at 0.1m of height from the base of the trunk were used. From each disk, with the aid of a band saw, a central ribbon 2.0cm wide, and oriented in the

  16. do parasita ao ecossistema

    OpenAIRE

    Balazeiro, Clementina Furtado

    2011-01-01

    A triquinose é uma zoonose parasitária, cujo agente causal, um nemátode, pertence ao género Trichinella. Foram já identificadas e caracterizadas várias espécies pertencentes a este género, como T. spiralis, T. nativa, T. britovi, T. nelsoni, T. murreli, T. pseudospiralis, T. papuae e T. zimbabwensis bem como alguns genótipos, T6, T8, T9, e T12. A triquinose é uma doença transmitida por carnivorismo entre os seus hospedeiros. No Homem, a principal fonte de infecção é o consumo de carne infecta...

  17. The risk of persistent trophoblastic disease after hydatidiform mole classified by morphology and ploidy

    DEFF Research Database (Denmark)

    Niemann, Isa; Hansen, Estrid S; Sunde, Lone

    2007-01-01

    OBJECTIVE: Hydatidiform mole can be classified by histopathologic characteristics and by genetic constitutions and most complete moles are diploid, whereas most partial moles are triploid. We investigated the concordance between these two classifications, characterized moles with conflicting...... classifications, and compared the ability of the two classifications to discriminate between patients with and without a substantial risk of persistent trophoblastic disease. METHODS: 294 cases of consecutively collected hydropic placentas clinically suspected of hydatidiform mole made the basis...... of this retrospective study. We determined the ploidy and reviewed the original histopathologic material in all cases. Data on possible chemotherapy were collected for each patient. RESULTS: 270 of the conceptuses were histopathologically classified as hydatidiform mole. Among the 24 conceptuses classified as non...

  18. O combate ao escorpionismo

    Directory of Open Access Journals (Sweden)

    Octavio de Magalhães

    1946-09-01

    Full Text Available O outor estuda os processos de combate aos acidentes pelas picadas dos escorpiões, visando: a Profilaxia e b Terapêutica. Refere-se à luta nos campos e nas cidades e aqui, dentro e fora dos domicílios. Assinala os diferentes métodos para o combate a êsses artrópodos peçonhentos. Fala na luta direta, indireta, na vacinação pelo anaveneno, na propaganda pela educação racional da população contra o perigo dos acidentes. Refere-se à "cata" dos escorpiões, à luta química, ao emprêgo de animais escorpiófagos, á feitura de casas e jardins anti-escorpiões. Na primeira parte do presente trabalho o autor trata da luta química pelo d. D. T. contra os tityus bahiensis e serrulatus, concluindo que êste corpo químico é um poderoso elemento de luta contra êstes escorpiões. Na segunda parte do trabalho, o autor trata da terapêutica dos acidentes. Mostra a necessidade do emprêgo convenientemente da única terapêutica racional e eficaz contra a intoxicação escorpiônica: a soroterapia específica. Assinala a necessidade da injeção de doses maciças de um sôro de alta valência, preparado em bovídeos, para evitar o mais possível o choque anafilático, no menor tempo possível após as picadas. Aconselha o empêgo de anaveneno escorpiônico, para vacinação principalmente de crianças de baixa idade, nos lugares fortemente infestados pelos escorpiões (principalmente Tityus serrulatus, maximé quando no local não houver sôro anti-escorpiônico específico, como meio preventivo contra a gravidade das intoxicações. Cita finalmente os trabalhos recentes de Grasset, Shaasfsma e Hodgson, na África do Sul, que confirmam muitas idéias do autor e mostram a unidade universal do síndromo escorpiônico descrito no Brasil.

  19. What's the Diagnosis? An Inquiry-Based Activity Focusing on Mole-Mass Conversions

    Science.gov (United States)

    Bruck, Laura B.; Towns, Marcy H.

    2011-01-01

    An inquiry-based mole-to-mass activity is presented associated with the analysis of blood. Students working in groups choose between two medical cases to determine if the "patient" has higher or lower concentrations of minerals than normal. The data are presented such that students must convert moles to mass in order to compare the patient values…

  20. Convergence vs. Specialization in the ear region of moles (Mammalia).

    Science.gov (United States)

    Crumpton, Nick; Kardjilov, Nikolay; Asher, Robert J

    2015-08-01

    We investigated if and how the inner ear region undergoes similar adaptations in small, fossorial, insectivoran-grade mammals, and found a variety of inner ear phenotypes. In our sample, afrotherian moles (Chrysochloridae) and the marsupial Notoryctes differ from most other burrowing mammals in their relatively short radii of semicircular canal curvature; chrysochlorids and fossorial talpids share a relatively long interampullar width. Chrysochlorids are unique in showing a highly coiled cochlea with nearly four turns. Extensive cochlear coiling may reflect their greater ecological dependence on low frequency auditory cues compared to talpids, tenrecids, and the marsupial Notoryctes. Correspondingly, the lack of such extensive coiling in the inner ear of other fossorial species may indicate a greater reliance on other senses to enable their fossorial lifestyle, such as tactile sensation from vibrissae and Eimer's organs. The reliance of chrysochlorids on sound is evident in the high degree of coiling and in the diversity of its mallear types, and may help explain the lack of any semiaquatic members of that group. The simplest mallear types among chrysochlorids are not present in the basal-most members of that clade, but all extant chrysochlorids investigated to date exhibit extensive cochlear coiling. The chrysochlorid ear region thus exhibits mosaic evolution; our data suggest that extensive coiling evolved in chrysochlorids prior to and independently of diversification in middle ear ossicle size and shape.

  1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat

    DEFF Research Database (Denmark)

    Kim, Eun Bae; Fang, Xiaodong; Fushan, Alexey A;

    2011-01-01

    The naked mole rat (Heterocephalus glaber) is a strictly subterranean, extraordinarily long-lived eusocial mammal. Although it is the size of a mouse, its maximum lifespan exceeds 30 years, making this animal the longest-living rodent. Naked mole rats show negligible senescence, no age......-related increase in mortality, and high fecundity until death. In addition to delayed ageing, they are resistant to both spontaneous cancer and experimentally induced tumorigenesis. Naked mole rats pose a challenge to the theories that link ageing, cancer and redox homeostasis. Although characterized...... by significant oxidative stress, the naked mole rat proteome does not show age-related susceptibility to oxidative damage or increased ubiquitination. Naked mole rats naturally reside in large colonies with a single breeding female, the 'queen', who suppresses the sexual maturity of her subordinates. They also...

  2. Hydatidiform mole and fetus with normal karyotype: support of a separate entity

    DEFF Research Database (Denmark)

    Vejerslev, L O; Sunde, L; Hansen, B F;

    1991-01-01

    Repetitive hydatidiform mole was observed in four pregnancies. The pregnancies presented with heavy bleeding and vomiting, but the post-evacuation courses were uncomplicated, with rapid regression of serum hCG levels. Cytogenetic investigations, analyses of restriction fragment length polymorphisms...... analysis was consistent with a single conception. With incomplete genetic information, a hydatidiform mole with coexistent normal fetus is generally considered to result from dizygous twinning comprising an androgenetic complete mole and a normal conception. In the present gestations, the results based...... on several techniques applied on numerous samples from different tissues render this possibility unlikely. Some of the contradictions between histologic and cytogenetic classifications of hydatidiform mole may be explained by diploid, biparental partial mole, which seems to constitute a separate subgroup...

  3. Acanthocephala Parasite (Profilicollis spp.) Loads in Correlation to Pacific Mole Crab (Emerita analoga) Size

    Science.gov (United States)

    Cheng, T.; Huang, S.; Galathe, M.; Jenkins, M.; Ramirez, A.; Crosby, L.; Barrera, J.; FitzHoward, S.

    2013-12-01

    Since 2002, San Francisco Bay students have been conducting marine ecosystem monitoring through a joint project with the Long-term Monitoring Program and Experiential Training for Students (LiMPETS), in conjunction with the Gulf of Farallones National Marine Sanctuary. Each year students collect population and demographic data on Pacific mole crabs (Emerita analoga), an indicator species that lives in the sandy beach habitat in temperate regions along the Pacific Ocean. Pacific mole crabs are filter feeding crustaceans that inhabit the intertidal swash zone and are known to be an intermediate host for parasitic ';spiny-headed' worms in the phylum Acanthocephala (Profilicollis spp.). Sampling takes place during their reproductive period, which occurs from spring to fall, and includes measuring total body length of the Pacific mole crabs and dissecting them to determine presence of Acanthocephalan parasites. We hypothesize that due to larger body mass, larger Pacific mole crabs will have a greater number of Acanthocephala parasites.We conducted several analyses using the LiMPETS long-term data. Specifically, we compared body length, crab gender, and parasite abundance from Pacific mole crabs sampled from four beaches located in the county and city of San Francisco. Our results indicated that larger Pacific mole crabs do not necessarily have more parasites, but are more likely to have at least one parasite, while female Pacific mole crabs carrying eggs, have more parasites than males or females without eggs. We also found that parasite loads per mole crab was highest in the spring. Further analysis will be conducted to determine factors affecting Pacific mole crab parasite loads. Studying Pacific mole crabs help evaluate the health of California's intertidal systems and how human activities, geologic changes, and climate changes all make huge impacts to the intertidal ecosystems.

  4. Traceability of pH to the Mole

    Directory of Open Access Journals (Sweden)

    Maria Filomena Camões

    2015-08-01

    Full Text Available Free acidity of aqueous solutions was initially defined in 1909 by Søren Peter Lauritz Sørensen as pH = −lgcH+ (c/mol·dm−3 or m/mol·kg−1 of the free hydrogen ions in solution, H+ soon (1910 was changed to pH = paH+ = −lgaH+, integrating the new concepts of activity, ai and activity coefficient γi, for the ionic species i under concern, H+ in this case; it is ai = −lg(miγi. Since individual ions do not exist alone in solution, primary pH values cannot be assigned solely by experimental measurements, requiring extra thermodynamic model assumptions for the activity coefficient, γH+, which has put pH in a unique situation of not being fully traceable to the International System of Units (SI. Also the concept of activity is often not felt to be as perceptible as that of concentration which may present difficulties, namely with the interpretation of data. pH measurements on unknown samples rely on calibration of the measuring setup with adequate reference pH buffers. In this work, the assignment of pH values to buffers closely matching the samples, e.g., seawater, is revisited. An approach is presented to assess the quantity pmH+ = −lgmH+ profiting from the fact that, contrary to single ion activity coefficients, mean activity coefficients,   can be assessed based on experimentally assessed quantities alone, γExp ±, thus ensuring traceability to the mole, the SI base unit for amount of substance. Compatibility between γExp ± and mean activity coefficient calculated by means of Pitzer model equations, γPtz ±, validates the model for its intended use.

  5. Assessment of naked mole-rat distribution and threats in Eastern Ethiopia

    Institute of Scientific and Technical Information of China (English)

    Mengistu Wale; Abeje Kassie; Tesfu Fekensa

    2016-01-01

    Objective:To identify the distribution, threats and community attitudes towards naked mole-rat in Eastern Ethiopia. Methods: Data were collected through direct observation and interview andChi-square at 95% confidence interval was used for significance test. Results:Naked mole-rat was identified in Fafan, City/Shinele,Eastern Hararghe Zone and Dire Dawa Administrative. The main threats of naked mole-rat identified were agricultural expansion, human killing and lack of awareness. Froma total of 100 respondents, 92% of them considered naked mole-rat as pest as a result that 46% of them participated in direct killing. Literacy rate significantly affects thewillingness to participate in the conservation of naked mole-rat (χ2 = 7.478,df = 1,P Conclusions:Naked mole-rat is fairly common in many of the study sites. However, rapid shift from nomadic life style to cultivation of crops and lacks of awareness were the main threats of naked mole-rat. Therefore, since there is no conservation action currently, further comprehensive study is required to design conservation plan for this species.

  6. Invasive mole of the uterus: A description of two cases managed by hysterectomy

    Directory of Open Access Journals (Sweden)

    Ahmed Samy El-agwany

    2015-12-01

    Full Text Available Gestational trophoblastic disease (GTD is a term used for a group of pregnancy-related tumors. Gestational trophoblastic neoplasia (GTN, is recognized as the most curable gynecologic malignancy. However, many cases are resistant to first line chemotherapy. We present cases of invasive mole. They were diagnosed as a vesicular mole on ultrasonography and underwent suction and evacuation but vaginal bleeding recurred with plateau and rising B-hcg with intramyometrial vascular lesion. Hysterectomy was done that indicated invasive mole. Patients were cured of their symptoms. Surgical therapy (hysterectomy with chemotherapy has shown to achieve remission in these cases especially with resistance to chemotherapy and in perimenopause.

  7. What Are Students' Initial Ideas about "Amount of Substance"? "Is There a Specific Weight for a Mole?"

    Science.gov (United States)

    Claesgens, Jennifer; Stacy, Angelica

    Analyzes the role of students' prior knowledge in their emerging understanding of the mole. The research question this study seeks to answer is what knowledge, if any, do student have regarding the mole and what prior knowledge do they access when presented problems regarding the nature of the mole. Data collection focuses on student knowledge…

  8. Clinical management and diagnostic possibilities in hydatidiform mole with coexistent fetus

    DEFF Research Database (Denmark)

    Vejerslev, L O

    1991-01-01

    The goal of the current review is to present the figures essential for counseling, when hydatidiform mole and normal fetus occur together. Previous reviews of prognosis and risks when mole and fetus are observed together did not adjust for differences in genetic constitution and thus varying risks...... for gynecologic and obstetric complications. A literature search from 1903 to 1989 revealed 113 reports of pregnancies with mole and fetus in which there appeared to be no major malformations or cytogenetic abnormalities; 87 of those were intended to continue. This group provides the most appropriate risk figures......, when mole and karyotypically normal child are detected by first or second trimester prenatal diagnosis. Fifty-two pregnancies (59.8 per cent) proceeded to the 28th week without spontaneous abortion or interruption of pregnancy. None of the children delivered before week 28 survived. Of the pregnancies...

  9. Perimenopausal invasive hyadatidiform mole treated by total abdominal hysterectomy followed by chemotherapy

    Science.gov (United States)

    Nakashima, Ayaka; Miyoshi, Ai; Miyatake, Takashi; Kazuhide, Ogita; Takeshi, Yokoi

    2016-01-01

    Gestational trophoblastic neoplasias (GTNs) are rare tumors that constitute mole of the uterus with metastasis to the right ovary and labium minus treated by total abdominal hysterectomy followed by chemotherapy. PMID:27651108

  10. Mammalian microevolution in action: adaptive edaphic genomic divergence in blind subterranean mole-rats.

    OpenAIRE

    Polyakov, Andrei; Beharav, Alex; Avivi, Aaron; Nevo, Eviatar

    2004-01-01

    Genomic diversity of anonymous regions across the genome, most probably including coding and noncoding amplified fragment length polymorphisms (AFLPs), was examined in 20 individuals of the blind mole-rat, Spalax galili, one of four allospecies of the Spalax ehrenbergi superspecies of blind subterranean mole-rats in Israel. We compared 10 individuals from two nearby populations in Upper Galilee, separated by only a few dozen to hundreds of metres and living in two sharply contrasting ecologie...

  11. RBM10 in complete hydatidiform mole: cytoplasmic occurrence of its 50 kDa polypeptide

    Directory of Open Access Journals (Sweden)

    Yutaka Inoue

    2013-04-01

    Full Text Available Background: RNA-binding motif protein 10 (RBM10, originally identified as S1-1 protein, is a nuclear protein with likely functions in transcription and RNA splicing. The RBM10 gene maps to the X chromosome and, in female cells, is inactivated in one of the two X chromosomes near the boundary with genes escaping inactivation. This study investigated the occurrence of the RBM10 gene product in complete hydatidiform mole, which is composed of cells with paternal diploid chromosomes (46, XX. Methods: Deparaffinized normal chorion or complete hydatidiform mole tissues were hybridized with a fluorescein-conjugated RBM10 gene probe in fluorescent in situ hybridization (FISH analysis. Immunohistochemistry and immunoelectron microscopy of the tissues were performed using an anti-RBM10 antiserum. Proteins from complete hydatidiform mole tissues and those separated by anti-RBM10-linked affinity chromatography were also examined by western blotting. Results: As expected, the RBM10 gene was detected by FISH as double spots in the nuclei of complete hydatidiform mole cells. Immunohistochemistry revealed a nuclear presence of RBM10 in normal chorion and complete hydatidiform moles, and a notable cytoplasmic presence in complete hydatidiform moles. Western blotting and immunoaffinity chromatography revealed that a 50 kDa protein was predominantly found in the cytosolic fraction of complete hydatidiform moles. Conclusions: A 50 kDa protein with common antigenicity to RBM10 was found in the cytoplasm of complete hydatidiform mole cells, and could represent one of the characteristics of the disease. [Int J Reprod Contracept Obstet Gynecol 2013; 2(2.000: 114-118

  12. Biodiesel From Canola Oil Using a 1:1 Mole Mixture of Methanol and Ethanol

    Science.gov (United States)

    Canola oil was transesterified using a 1:1 mole mixture of methanol and ethanol (M/E) with potassium hydroxide (KOH) catalyst. Effect of catalyst concentration (0.5 to 1.5% wt/wt), mole ratio of M/E to canola oil (3:1 to 20:1) and reaction temperature (25 to 75°C) on the percentage yield measured af...

  13. Management of pest mole crickets in Florida and Puerto Rico with a nematode and parasitic wasp

    International Nuclear Information System (INIS)

    Non-indigenous invasive mole crickets, Scapteriscus vicinus Scudder (Orthoptera: Gryllotalpidae) in Florida and S. didactylus (Latreille) (the 'changa') in Puerto Rico, are being managed with an entomopathogenic nematode, Steinernema scapterisci (Nguyen and Smart) (Rhabditida: Steinernematidae), and a parasitic wasp, Larra bicolor L. (Hymenoptera: Sphecidae). Pest mole cricket populations have declined by 95% in north central Florida since these specialist natural enemies were released and established in the 1980s. Commercial production of the nematode was initiated, nearly 70 billion were applied in 34 Florida counties, and their establishment, spread, and impact on mole crickets were monitored. The infected mole crickets dispersed the nematode rapidly, so that within 6 months these parasites were present in most of the insects trapped in experimental pastures. Three years later, mole cricket populations were reduced to acceptable levels and the bahiagrass had recovered. The nematode was released for the first time in Puerto Rico during 2001 and has persisted; the wasp was introduced in the late 1930s. The geographical distribution of the wasp is being expanded in Florida and Puerto Rico by planting plots of Spermacoce verticillata (L.), a wildflower indigenous to Puerto Rico and widely distributed in southern Florida. Pastures, sod farms, golf courses, landscapes, and vegetable farms in Florida and Puerto Rico are benefiting from biological control of invasive mole crickets. (author)

  14. Detection of Homozygous Deletions and Mutations in the CDKN2A Gene in Hydatidiform Moles

    Institute of Scientific and Technical Information of China (English)

    Jing Wang; Shuying Wu; Ying Gu; Yan Zhu; Xiaowei Zhang

    2008-01-01

    OBJECTIVE To investigate homozygous deletions and mutations in the CDKN2A gene (p16INK4a and p14ARF gene) in hydatidiform moles.METHODS A total of 38 hydatidiform mole samples and 30 villi samples were examined for homozygous deletions in the CDKN2A gene by PCR and for mutations by DHPLC.RESULTS I) Among 38 hydatidiform mole samples,homozygous deletions in the p16INK4a exon 1 were identified in 5 cases (13.2%), while no homozygous deletions were found in the p16INK4a exon 1 of 30 early-pregnancy samples. The rates of those deletions in hydatidiform compared to early-pregnancy villi samples was statistically significant (P = 0.036). Ii) No homozygous deletions in the p14ARF exon 1 or p16INK4a exon 2 were found in any of the hydatidiform moles or early-preganancy samples, iii)In all hydatidiform moles and early-pregnancy villi samples, no mutations were detected by DHPLC.CONCLUSION We suggest there may be a close correlation between homozygous deletions in the CDKN2A gene and occurrence of hydatidiform moles variation in the CDKN2A gene is mainly caused by homozygous deletions, while mutations may be not a major cause.

  15. The Mole as an Explanatory Device: How Do You Know a Mole if You See One? A Manual for Chemistry Students. Sample Teaching Materials: The Explanatory Modes Project.

    Science.gov (United States)

    Roberts, Douglas A.

    This booklet is designed to supplement the study of introductory chemistry. It deals particularly with the mole concept but also includes ideas for analyzing the kinds of statements that appear in all science textbooks and scientific writing. The material in the booklet should be studied after the completion of an introductory textbook study of…

  16. MEMS AO for Planet Finding

    Science.gov (United States)

    Rao, Shanti; Wallace, J. Kent; Shao, Mike; Schmidtlin, Edouard; Levine, B. Martin; Samuele, Rocco; Lane, Benjamin; Chakrabarti, Supriya; Cook, Timothy; Hicks, Brian; Jung, Paul

    2008-01-01

    This slide presentation reviews a method for planet finding using microelectromechanical systems (MEMS) Adaptive Optics (AO). The use of a deformable mirror (DM) is described as a part of the instrument that was designed with a nulling interferometer. The strategy that is used is described in detail.

  17. iMole, a web based image retrieval system from biomedical literature.

    Science.gov (United States)

    Giordano, Manuela; Natale, Massimo; Cornaz, Moreno; Ruffino, Andrea; Bonino, Dario; Bucci, Enrico M

    2013-07-01

    iMole is a platform that automatically extracts images and captions from biomedical literature. Images are tagged with terms contained in figure captions by means of a sophisticate text-mining tool. Moreover, iMole allows the user to upload directly their own images within the database and manually tag images by curated dictionary. Using iMole the researchers can develop a proper biomedical image database, storing the images extracted from paper of interest, image found on the web repositories, and their own experimental images. In order to show the functioning of the platform, we used iMole to build a 2DE database. Briefly, tagged 2DE gel images were collected and stored in a searchable 2DE gel database, available to users through an interactive web interface. Images were obtained by automatically parsing 16,608 proteomic publications, which yielded more than 16,500 images. The database can be further expanded by users with images of interest trough a manual uploading process. iMole is available with a preloaded set of 2DE gel data at http://imole.biodigitalvalley.com.

  18. Oxygen-Binding Characteristics of Hemoglobins from Hypoxia and Hypercapnia Tolerant African Mole Rats

    DEFF Research Database (Denmark)

    Weber, Roy E.; Jarvis, Jennifer U. M; Fago, Angela;

    2016-01-01

    Inhabiting complex, deep and sealed burrow systems, mole rats exhibit a suit of striking anatomical, behavioral and physiological specializations, including eusociality (living in large colonies with a single breeding ‘queen’), extraordinary longevity, variable body temperatures, high immunity...... transport of respiratory gases, we analysed hematological characters, as well as the Hb-O2 affinities and their sensitivities to pH (the Bohr effect), CO2, temperature and to the major red cell allosteric effector, DPG, in 4 eusocial and 2 strictly-solitary species of African mole rats (family Bathyergidae...... pulmonary Hb-O2 loading under hypercapnic and hypoxic burrows. The results are discussed in relation to the limited, available information on the primary structures on mole rat Hbs....

  19. A Mole for Warm Magnetic and Optical Measurements of LHC Dipoles

    CERN Document Server

    Bottura, L; Deferne, G; Glöckner, C; Jansen, H; Köster, A; Legrand, P; Rijllart, A; Sievers, P

    2000-01-01

    A new rotating coil probe (a mole) has been developed for the simultaneous measurement of the magnetic field and magnetic axis of warm superconducting LHC dipoles and associated corrector windings. The mole houses a radial rotating coil and travels inside the magnet aperture by means of an externally driven two-way traction belt. The coil is rotated by an on-board piezo motor, being tested in view of future devices for cold measurements as the only type of motor compatible with strong magnetic fields. A virtual light spot is generated in the coil center by a LED source. The position of this light spot is measured from the outside by a system including a telescope, a CCD camera and a DSP. Jigs on reference granite tables are used to transfer the optical measurements to the magnet fiducials. We describe here the main characteristics and performance of the mole

  20. Low and Maternal-specific Expression of p57KIP2 in Hydatidiform Mole and Its Clinical Implication

    Institute of Scientific and Technical Information of China (English)

    熊雅丽; 曹阳; 李红发

    2002-01-01

    Summary: In situ hybridization was applied to locate and detect the expression of p57KIP2 in hydatidi form mole (5 cases of partial hydatidiform mole and 18 cases of complete hydatidiform mole) and nor-mal villi (23 cases). The positive signals of p57KIP2 expression were analyzed by HPIAS-1000 Image Analysis System. p57KIP2 was highly expressed in normal villi but showed distinct low expression in hydatidiform mole (P<0. 01). Furthermore, the locus of low expression of p57KIP2 accorded with the place where lesion of trophoblast occurred. Detection of p57KIP2 made it possible to study the genetics of hydatidiform mole at the transcriptional level. Low expression of p57IP2 could be a molecular marker in hydatidiform mole and a target for therapy.

  1. Mechanical performance of rat, mouse and mole spring traps, and possible implications for welfare performance.

    Directory of Open Access Journals (Sweden)

    Sandra E Baker

    Full Text Available Lethal spring traps are widely used for killing small mammals in the UK. Many require government approval, based primarily on humaneness. However, mole traps and break-back traps for rats and mice are exempt; those available vary widely in price and apparent quality. The EU is considering implementing a Trapping Directive that would alter UK legislation, and a recent report advised the EU that trapping legislation should cover all trapped species and encourage improvement of traps. Mechanical trap performance is often used as an indicator of welfare impact. We examined the mechanical evidence for scope to improve the welfare standards of rat, mouse and mole spring traps. We measured mechanical performance among a range of rat, mouse and mole traps. Impact momentum values varied 6-8 fold, and clamping force values 4-5.5 fold, among traps for killing each species. There was considerable overlap in the performance of rat and mouse traps. Trap-opening angle and spring type were related to impact momentum and clamping force in traps for both species. There was no relationship between price and mechanical performance in traps for any species, except talpa mole traps. We are unable to judge the direct welfare impact of the traps tested, but rather the potential welfare threat associated with their exemption from approval. The wide variation in mechanical performance in traps for each species, overlap in performance between rat and mouse traps and increasing availability of weaker plastic rodent traps indicate considerable scope for improving the humaneness of spring traps for rats, mice and moles. We conclude that all such traps should be subject to the UK approval process. New welfare categories might improve trap standards further. Our results could also help improve rodent trap design and assist consumers in selecting more powerful traps. Many thousands of rats, mice and moles might benefit.

  2. Mole ghrelin: cDNA cloning, gene expression, and diverse molecular forms in Mogera imaizumii.

    Science.gov (United States)

    Satou, Motoyasu; Kaiya, Hiroyuki; Nishi, Yoshihiro; Shinohara, Akio; Kawada, Shin-Ichiro; Miyazato, Mikiya; Kangawa, Kenji; Sugimoto, Hiroyuki

    2016-06-01

    Here, we describe cDNA cloning and purification of the ghrelin gene sequences and ghrelin peptides from the Japanese true mole, Mogera imaizumii. The gene spans >2.9kbp, has four exons and three introns, and shares structural similarity with those of terrestrial animals. Mature mole ghrelin peptide was predicted to be 28 amino acids long (GSSFLSPEHQKVQQRKESKKPPSKPQPR) and processed from a prepropeptide of 116 amino acids. To further elucidate molecular characteristics, we purified ghrelin peptides from mole stomach. By mass spectrometry, we found that the mole ghrelin peptides had higher ratios of the odd-number fatty acids (C9 and C11 as much as C8) attached to the third serine residue than other vertebrate ghrelin. Truncated forms of ghrelins such as [1-27], [1-19], [1-16] and [1-15], and that lacked the 14th glutamine residue (des-Gln14 ghrelin) were produced in the stomach. Marked expression of ghrelin mRNA in lung was observed as in stomach and brain. Phylogenetic analysis indicated that the branch of M. imaizumii has slightly higher dN/dS ratios (the nucleotide substitution rates at non-synonymous and synonymous sites) than did other eulipotyphlans. Peptide length was positively correlated with human ghrelin receptor activation, whereas the length of fatty-acyl chains showed no obvious functional correlation. The basal higher luciferase activities of the 5'-proximal promoter region of mole ghrelin were detected in ghrelin-negative C2C12 cells and hypoxic culture conditions impaired transcriptional activity. These results indicated that moles have acquired diverse species of ghrelin probably through distinctive fatty acid metabolism because of their food preferences. The results provide a gateway to understanding ghrelin metabolism in fossorial animals. PMID:27102942

  3. Extended longevity of reproductives appears to be common in Fukomys mole-rats (Rodentia, Bathyergidae.

    Directory of Open Access Journals (Sweden)

    Philip Dammann

    Full Text Available African mole-rats (Bathyergidae, Rodentia contain several social, cooperatively breeding species with low extrinsic mortality and unusually high longevity. All social bathyergids live in multigenerational families where reproduction is skewed towards a few breeding individuals. Most of their offspring remain as reproductively inactive "helpers" in their natal families, often for several years. This "reproductive subdivision" of mole-rat societies might be of interest for ageing research, as in at least one social bathyergid (Ansell's mole-rats Fukomys anselli, breeders have been shown to age significantly slower than non-breeders. These animals thus provide excellent conditions for studying the epigenetics of senescence by comparing divergent longevities within the same genotypes without the inescapable short-comings of inter-species comparisons. It has been claimed that many if not all social mole-rat species may have evolved similar ageing patterns, too. However, this remains unclear on account of the scarcity of reliable datasets on the subject. We therefore analyzed a 20-year breeding record of Giant mole-rats Fukomys mechowii, another social bathyergid species. We found that breeders indeed lived significantly longer than helpers (ca. 1.5-2.2fold depending on the sex, irrespective of social rank or other potentially confounding factors. Considering the phylogenetic positions of F. mechowii and F. anselli and unpublished data on a third Fukomys-species (F. damarensis showing essentially the same pattern, it seems probable that the reversal of the classic trade-off between somatic maintenance and sexual reproduction is characteristic of the whole genus and hence of the vast majority of social mole-rats.

  4. Torsion theca lutein cyst in association with invasive mole presenting as acute abdomen: a rare case

    Directory of Open Access Journals (Sweden)

    Radhamani S.

    2015-08-01

    Full Text Available Gestational trophoblastic neoplasias (GTN are rare tumours that constitute less than 1% of all gynaecological malignancies. Invasive mole is a distinct subgroup of GTN, which if not diagnosed and treated early, can result in serious complications like uterine perforation and haemoperitoneum. We present a rare case of torsion theca lutein cyst in association with invasive mole of the uterus, which developed following the evacuation of a molar pregnancy with features of continued irregular vaginal bleeding, persistently high betaHcg levels along with acute abdomen. [Int J Reprod Contracept Obstet Gynecol 2015; 4(4.000: 1237-1240

  5. Hydatidiform mole and fetus with normal karyotype: support of a separate entity

    DEFF Research Database (Denmark)

    Vejerslev, L O; Sunde, L; Hansen, B F;

    1991-01-01

    , and flow cytometry in three pregnancies were consistent with diploid, biparental conception as the origin of fetal tissue and molar and nonmolar villi. In one pregnancy, the analyses of cytogenetic markers suggested the coexistence of two different cell lines of dizygotic, biparental origin, whereas DNA...... analysis was consistent with a single conception. With incomplete genetic information, a hydatidiform mole with coexistent normal fetus is generally considered to result from dizygous twinning comprising an androgenetic complete mole and a normal conception. In the present gestations, the results based...

  6. Twin pregnancy with both complete hydatiform mole and coexistent alive fetus:case report

    Institute of Scientific and Technical Information of China (English)

    Achour Radhouane; Ben Aissa Imen; NEJI Khaled

    2015-01-01

    Twin pregnancy consisting of a complete hydatidiform mole coexisting with a live fetus is a rare condition with an incidence of 1 in 22 000 to 1 in 1 00 000 pregnancies. Clinical information is limited and management is difficult due to the risk of pregnancy complications such as fetal death, vaginal bleeding, preeclampsia, hyperthyroidism, and the risk of persistent gestational trophoblastic disease. Thus, the report described about the change of size and implantation site of the molar mass coexisting with a live fetus is rare especially about sonographic findings such as echo patterns. Recently we experienced a case of complete hydatidiform mole with a healthy infant delivered at term.

  7. Host switch during evolution of a genetically distinct hantavirus in the American shrew mole (Neurotrichus gibbsii).

    Science.gov (United States)

    Kang, Hae Ji; Bennett, Shannon N; Dizney, Laurie; Sumibcay, Laarni; Arai, Satoru; Ruedas, Luis A; Song, Jin-Won; Yanagihara, Richard

    2009-05-25

    A genetically distinct hantavirus, designated Oxbow virus (OXBV), was detected in tissues of an American shrew mole (Neurotrichus gibbsii), captured in Gresham, Oregon, in September 2003. Pairwise analysis of full-length S- and M- and partial L-segment nucleotide and amino acid sequences of OXBV indicated low sequence similarity with rodent-borne hantaviruses. Phylogenetic analyses using maximum-likelihood and Bayesian methods, and host-parasite evolutionary comparisons, showed that OXBV and Asama virus, a hantavirus recently identified from the Japanese shrew mole (Urotrichus talpoides), were related to soricine shrew-borne hantaviruses from North America and Eurasia, respectively, suggesting parallel evolution associated with cross-species transmission. PMID:19394994

  8. Combate ao niilismo e ao totalitarismo em Camus

    Directory of Open Access Journals (Sweden)

    Emanuel Ricardo Germano

    2013-05-01

    Full Text Available A partir de uma leitura da peça Calígula, elaborada entre 1941 e 1943, procurar-se-á contribuir na restituição das preocupações éticas, políticas e filosóficas em cena no teatro de Albert Camus, analisando o sentido de sua expressão teatral no contexto de dois combates,ao niilismo filosófico e ao totalitarismo político de seu tempo. Observaremos em Calígula um importante registro do amadurecimento das leituras de duas heranças filosóficas relevantes na formação intelectual de Camus, Nietzsche e Heráclito, à luz da experiência do totalitarismo, observando e ressaltando com isso a amplitude de seu intertexto filosófico e a importância do aporte ético e político de Camus como pensador multifacetado, engajado nos enfrentamentos históricos e solicitações críticas de seu tempo.

  9. Family Wide Molecular Adaptations to Underground Life in African Mole-Rats Revealed by Phylogenomic Analysis.

    Science.gov (United States)

    Davies, Kalina T J; Bennett, Nigel C; Tsagkogeorga, Georgia; Rossiter, Stephen J; Faulkes, Christopher G

    2015-12-01

    During their evolutionary radiation, mammals have colonized diverse habitats. Arguably the subterranean niche is the most inhospitable of these, characterized by reduced oxygen, elevated carbon dioxide, absence of light, scarcity of food, and a substrate that is energetically costly to burrow through. Of all lineages to have transitioned to a subterranean niche, African mole-rats are one of the most successful. Much of their ecological success can be attributed to a diet of plant storage organs, which has allowed them to colonize climatically varied habitats across sub-Saharan Africa, and has probably contributed to the evolution of their diverse social systems. Yet despite their many remarkable phenotypic specializations, little is known about molecular adaptations underlying these traits. To address this, we sequenced the transcriptomes of seven mole-rat taxa, including three solitary species, and combined new sequences with existing genomic data sets. Alignments of more than 13,000 protein-coding genes encompassed, for the first time, all six genera and the full spectrum of ecological and social variation in the clade. We detected positive selection within the mole-rat clade and along ancestral branches in approximately 700 genes including loci associated with tumorigenesis, aging, morphological development, and sociality. By combining these results with gene ontology annotation and protein-protein networks, we identified several clusters of functionally related genes. This family wide analysis of molecular evolution in mole-rats has identified a suite of positively selected genes, deepening our understanding of the extreme phenotypic traits exhibited by this group.

  10. The Atomic Mass Unit, the Avogadro Constant, and the Mole: A Way to Understanding

    Science.gov (United States)

    Baranski, Andrzej

    2012-01-01

    Numerous articles have been published that address problems encountered in teaching basic concepts of chemistry such as the atomic mass unit, Avogadro's number, and the mole. The origin of these problems is found in the concept definitions. If these definitions are adjusted for teaching purposes, understanding could be improved. In the present…

  11. Identifying the Critical Components for a Conceptual Understanding of the Mole in Secondary Science Classrooms

    Science.gov (United States)

    Fang, Su-Chi; Hart, Christina; Clarke, David

    2016-01-01

    The amount of substance and its unit the mole is a basic concept in chemistry. However, previous research has shown that teaching and learning the concept are challenging tasks for both teachers and students. The purpose of this study was to pinpoint the problems which emerge in the teaching and learning process, and provide integrated suggestions…

  12. Trauma and humanitarian translation in Liberia: the tale of open mole.

    Science.gov (United States)

    Abramowitz, Sharon Alane

    2010-06-01

    The focus of this paper is the intercultural process through which Open Mole and trauma-related mental illnesses are brought together in the postconflict mental health encounter. In this paper, I explore the historical dimension of this process by reviewing the history of Open Mole, and the ways in which it has been interpreted, acted on, and objectified by external observers over the last half-century. Moving into Liberia's recent war and postconflict period, I examine the process by which Open Mole is transformed from a culture-bound disorder into a local idiom of trauma, and how it has become a gateway diagnosis of PTSD-related mental illnesses, and consider how it is produced as an objectified experience of psychiatric disorder in clinical humanitarian contexts. By studying how Open Mole is transformed in the humanitarian encounter, I address the structure and teleology of the humanitarian encounter and challenge some of the foundational assumptions about cultural sensitivity and community-based mental health care in postconflict settings that are prevalent in scholarship and practice today. PMID:20401629

  13. Background Mole Fractions of Hydrocarbons in North America Determined from NOAA Global Reference Network Data

    Science.gov (United States)

    Mielke-Maday, I.

    2015-12-01

    The National Oceanic and Atmospheric Administration (NOAA) Global Monitoring Division (GMD) maintains a global reference network for over 50 trace gas species and analyzes discrete air samples collected by this network throughout the world at the Earth System Research Laboratory in Boulder, Colorado. In particular, flask samples are analyzed for a number of hydrocarbons with policy and health relevance such as ozone precursors, greenhouse gases, and hazardous air pollutants. Because this global network's sites are remote and therefore minimally influenced by local anthropogenic emissions, these data yield information about background ambient mole fractions and can provide a context for observations collected in intensive field campaigns, such as the Front Range Air Pollution and Photochemistry Experiment (FRAPPE), the Southeast Nexus (SENEX) study, and the DISCOVER-AQ deployments. Information about background mole fractions during field campaigns is critical for calculating hydrocarbon enhancements in the region of study and for assessing the extent to which a particular region's local emissions sources contribute to these enhancements. Understanding the geographic variability of the background and its contribution to regional ambient mole fractions is also crucial for the development of realistic regulations. We present background hydrocarbon mole fractions and their ratios in North America using data from air samples collected in the planetary boundary layer at tall towers and aboard aircraft from 2008 to 2014. We discuss the spatial and seasonal variability in these data. We present trends over the time period of measurements and propose possible explanations for these trends.

  14. Reading about the Power of Music: "Mole Music" and "Children of the Stone"

    Science.gov (United States)

    Cardany, Audrey Berger

    2016-01-01

    In this article, I review two books that address the power of music for the individual and group. Both books address the benefits of making, learning, and listening to music during times of conflict. The first brief review is David McPhail's picture book "Mole Music." The second is "Children of the Stone: The Power of Music in a…

  15. Comparative analysis of genome maintenance genes in naked mole rat, mouse, and human

    NARCIS (Netherlands)

    S.L. Macrae (Sheila L.); Q. Zhang (Quanwei); C. Lemetre (Christophe); I. Seim (Inge); R.B. Calder (Robert B.); J.H.J. Hoeijmakers (Jan); Y. Suh (Yousin); V.N. Gladyshev (Vadim N.); A. Seluanov (Andrei); V. Gorbunova (Vera); J. Vijg (Jan); Z.D. Zhang (Zhengdong D.)

    2015-01-01

    textabstractGenome maintenance (GM) is an essential defense system against aging and cancer, as both are characterized by increased genome instability. Here, we compared the copy number variation and mutation rate of 518 GM-associated genes in the naked mole rat (NMR), mouse, and human genomes. GM g

  16. Efeito da mobilização de tecidos moles nas concentrações de ácido láctico, após exercício intensivo

    OpenAIRE

    Brito, Juliana Alves; Leite, Pedro Harry; Paquete, Manuel

    2011-01-01

    Objectivo do estudo: verificar o efeito da mobilização dos tecidos moles nas concentrações de ácido láctico, após exercício intensivo. Critérios de exclusão: lesão ou cirurgia ao nível do membro inferior dominante; presença de qualquer doença neurológica, dermatológica, sistémica, cardiovascular ou vascular periférica; dor ao nível da musculatura em avaliação; não realizar qualquer tipo de tratamentos de Fisioterapia.

  17. Unraveling the message: insights into comparative genomics of the naked mole-rat.

    Science.gov (United States)

    Lewis, Kaitlyn N; Soifer, Ilya; Melamud, Eugene; Roy, Margaret; McIsaac, R Scott; Hibbs, Matthew; Buffenstein, Rochelle

    2016-08-01

    Animals have evolved to survive, and even thrive, in different environments. Genetic adaptations may have indirectly created phenotypes that also resulted in a longer lifespan. One example of this phenomenon is the preternaturally long-lived naked mole-rat. This strictly subterranean rodent tolerates hypoxia, hypercapnia, and soil-based toxins. Naked mole-rats also exhibit pronounced resistance to cancer and an attenuated decline of many physiological characteristics that often decline as mammals age. Elucidating mechanisms that give rise to their unique phenotypes will lead to better understanding of subterranean ecophysiology and biology of aging. Comparative genomics could be a useful tool in this regard. Since the publication of a naked mole-rat genome assembly in 2011, analyses of genomic and transcriptomic data have enabled a clearer understanding of mole-rat evolutionary history and suggested molecular pathways (e.g., NRF2-signaling activation and DNA damage repair mechanisms) that may explain the extraordinarily longevity and unique health traits of this species. However, careful scrutiny and re-analysis suggest that some identified features result from incorrect or imprecise annotation and assembly of the naked mole-rat genome: in addition, some of these conclusions (e.g., genes involved in cancer resistance and hairlessness) are rejected when the analysis includes additional, more closely related species. We describe how the combination of better study design, improved genomic sequencing techniques, and new bioinformatic and data analytical tools will improve comparative genomics and ultimately bridge the gap between traditional model and nonmodel organisms. PMID:27364349

  18. No evidence for mutations in NLRP7 and KHDC3L in women with androgenetic hydatidiform moles

    Science.gov (United States)

    The objective of this study was to evaluate the mutational spectrum of NLRP7 and KHDC3L (C6orf221) in women with sporadic and recurrent androgenetic complete hydatidiform moles (AnCHM) and biparental hydatidiform moles (BiHM) to address the hypothesis that autosomal recessive mutations in these gene...

  19. Dahonggou Creek virus, a divergent lineage of hantavirus harbored by the long-tailed mole (Scaptonyx fusicaudus).

    Science.gov (United States)

    Kang, Hae Ji; Gu, Se Hun; Cook, Joseph A; Yanagihara, Richard

    2016-01-01

    Novel hantaviruses, recently detected in moles (order Eulipotyphla, family Talpidae) from Europe, Asia, and North America would predict a broader host range and wider ecological diversity. Employing RT-PCR, archival frozen tissues from the Chinese shrew mole (Uropsilus soricipes), broad-footed mole (Scapanus latimanus), coast mole (Scapanus orarius), Townsend's mole (Scapanus townsendii), and long-tailed mole (Scaptonyx fusicaudus) were analyzed for hantavirus RNA. Following multiple attempts, a previously unrecognized hantavirus, designated Dahonggou Creek virus (DHCV), was detected in a long-tailed mole, captured in Shimian County, Sichuan Province, People's Republic of China, in August 1989. Analyses of a 1058-nucleotide region of the RNA-dependent RNA polymerase-encoding L segment indicated that DHCV was genetically distinct from other rodent-, shrew-, mole-, and bat-borne hantaviruses. Phylogenetic trees, using maximum likelihood and Bayesian methods, showed that DHCV represented a divergent lineage comprising crocidurine and myosoricine shrew-borne hantaviruses. Although efforts to obtain the S- and M-genomic segments failed, the L-segment sequence analysis, reported here, expands the genetic database of non-rodent-borne hantaviruses. Also, by further mining natural history collections of archival specimens, the genetic diversity of hantaviruses will elucidate their evolutionary origins. PMID:27433135

  20. Aerosol Observing System (AOS) Handbook

    Energy Technology Data Exchange (ETDEWEB)

    Jefferson, A

    2011-01-17

    The Aerosol Observing System (AOS) is a suite of in situ surface measurements of aerosol optical and cloud-forming properties. The instruments measure aerosol properties that influence the earth’s radiative balance. The primary optical measurements are those of the aerosol scattering and absorption coefficients as a function of particle size and radiation wavelength and cloud condensation nuclei (CCN) measurements as a function of percent supersaturation. Additional measurements include those of the particle number concentration and scattering hygroscopic growth. Aerosol optical measurements are useful for calculating parameters used in radiative forcing calculations such as the aerosol single-scattering albedo, asymmetry parameter, mass scattering efficiency, and hygroscopic growth. CCN measurements are important in cloud microphysical models to predict droplet formation.

  1. Mole (Nevus)

    Science.gov (United States)

    ... melanoma). Remember the ABCDEs of melanoma lesions: A - Asymmetry: One half of the lesion does not mirror ... McGraw-Hill, 2003. Last Updated: 23 Jul 2010 Information for other ages: Child Teen Table of Contents: ...

  2. Analysis of internal doses to Mole voles inhabiting the East-Ural radioactive trace

    Energy Technology Data Exchange (ETDEWEB)

    Malinovsky, G.; Yarmoshenko, I. [Institute of Industrial Ecology UB RAS (Russian Federation); Chibiryak, M.; Vasil' ev, A. [Institute of Plant and Animal Ecology UB RAS (Russian Federation)

    2014-07-01

    Substantial task of development of approaches to radiation protection of non-human biota is investigation of relationships of exposure to dose, and dose to effects. Small mammals inhabiting territory of the East-Ural Radioactive Trace (EURT) are affected to ionizing radiation for many generations after accident at Mayak plutonium production in 1957. According to results of numerous studies a number of effects of exposure are observed. It is remarkable that the revealed effects are both negative and adaptive. In particular, the analysis of the variability of morphological structures of the axial skull and lower jaw in the population of northern mole vole (Ellobius talpinus Pall.), the burrowing rodent inhabiting the EURT, is of great interest. At the same time there is no reliable assessment of the radiation doses to these animals. Earlier we developed the approach to assess internal doses to mouse-like rodents (mice and voles) caused by incorporated {sup 90}Sr, which is the main dose contributing radionuclide at the EURT. Dose assessments are based on the results of beta-radiometry of intact bone. Routine methods for measuring the activity concentration of {sup 90}Sr in skeleton require ashing of samples, however in morphometric studies the destruction of material should be avoided: the skulls of mole voles are stored in the environmental samples depository of IPAE. Coefficients linking results of beta-radiometry of intact bone and activity concentration of {sup 90}Sr in skull of mouse was obtained basing on comparison of results of beta-radiometry of intact bone and bone ash. Obtained coefficients cannot be directly applied for calculating activity concentration of {sup 90}Sr in mole vole skulls because they are significantly larger. Therefore the additional study is required to assess proper coefficient of conversion from beta-radiometry to activity concentration of {sup 90}Sr. Developed dose assessment procedure includes application of the published values of

  3. Genetics and Epigenetics of Recurrent Hydatidiform Moles: Basic Science and Genetic Counselling.

    Science.gov (United States)

    Nguyen, Ngoc Minh Phuong; Slim, Rima

    2014-01-01

    Gestational trophoblastic disease (GTD) is a group of conditions that originate from the abnormal hyperproliferation of trophoblastic cells, which derive from the trophectoderm, the outer layer of the blastocyst that would normally develop into the placenta during pregnancy. GTDs encompass hydatidiform mole (HM) (complete and partial), invasive mole, gestational choriocarcinoma, placental-site trophoblastic tumor, and epithelioid trophoblastic tumor. Of these, the most common is HM, and it is the only one that has been reported to recur in the same patients from independent pregnancies, which indicates the patients' genetic predisposition. In addition, HM is the only GTD that segregates in families according to Mendel's laws of heredity, which made it possible to use rare familial cases of recurrent HMs (RHMs) to identify two maternal-effect genes, NLRP7 and KHDC3L, responsible for this condition. Here, we recapitulate current knowledge about RHMs and conclude with the role and benefits of testing patients for mutations in the known genes.

  4. Preliminary Study on c-Ha-ras Oncogene Mutations in Hydatidiform Mole Tissues

    Institute of Scientific and Technical Information of China (English)

    王芳; 谭运年; 陈碧; 李英勇; 康旭

    2001-01-01

    Objective To study the presence of c-Ha-fas oncogene mutations in hydatidiform mole (HM) tissues and to further explore its relationship with mole's malignancy Materials & methods c-Ha-ras codon 12 mutation was detected in invasive and noninvasive HM by using polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP).Results c-Ha-fas codon 12 mutation was detected in 7 samples (53. 85%) of 13 invasive HM and 8 samples (26. 67%) in 30 non-invasive HM. c-Ha-ras mutations also showed loss of wild-type c-Ha-fas. No mutation in control group was observed.Conclusion The tendency of c-Ha-ras codon 12 mutation may be related with a higher invasive degree of HM.

  5. Effects of ultraviolet radiation on mole rats kidney: A histopathologic and ultrastructural study

    Directory of Open Access Journals (Sweden)

    Hüseyin Türker

    2014-04-01

    Full Text Available The purpose of this study was to realize the ultrastructural effects of ultraviolet radiation on the kidney tissue cells of mole rats (Spalax leucodon. The mole rats of 180–200 g body weight were divided into the control and radiation-trial groups. The control group was not given any radiation. The other groups were irradiated with artificially produced UVC radiation for 14, 28 and 60 days. The kidney tissue samples were prepared at the end of experiments and analyzed by the light and electron microscope. Several effects were observed in the kidney tissues cells analyzed in accordance with the dose magnitude of radiation. These results clearly show the detrimental effects of UVC radiation on kidney tissue cells in exposure periods dependent on radiation dose and exposure time.

  6. Seasonal changes in burrow geometry of the common mole rat (Rodentia: Bathyergidae)

    Science.gov (United States)

    Thomas, H. G.; Scantlebury, M.; Swanepoel, D.; Bateman, P. W.; Bennett, N. C.

    2013-11-01

    Sociality in mole rats has been suggested to have evolved as a response to the widely dispersed food resources and the limited burrowing opportunities that result from sporadic rainfall events. In the most arid regions, individual foraging efficiency is reduced, and energetic constraints increase. In this study, we investigate seasonal differences in burrow architecture of the social Cryptomys hottentotus hottentotus in a mesic region. We describe burrow geometry in response to seasonal weather conditions for two seasons (wet and dry). Interactions occurred between seasons and colony size for the size of the burrow systems, but not the shape of the burrow systems. The fractal dimension values of the burrow systems did not differ between seasons. Thus, the burrow complexity was dependent upon the number of mole rats present in the social group.

  7. On the Mole-Rat (Cryptomys Hottentotus Damarensis (Rodentia in the Kalahari Gemsbok National Park

    Directory of Open Access Journals (Sweden)

    G de Graaff

    1972-01-01

    Full Text Available Aspects of the ecology and distribution of the Damara mole-rat (Cryptomys hottentotus damarensis are discussed relative to its life in the arid Kalahari Gemsbok National Park. The value of coat colour as a taxonomic criterion for the subspecies is discussed. Notes are also presented on reproduction, aspects of behaviour such as: habitat, nests, orientation, activity, locomotion, voice, food, feeding and social life, symbiosis, commensalism, parasites and predators.

  8. Genome sequencing reveals insights into physiology and longevity of the naked mole rat

    OpenAIRE

    Kim, Eun Bae; Fang, Xiaodong; Fushan, Alexey A.; Huang, Zhiyong; Lobanov, Alexei V.; Han, Lijuan; Marino, Stefano M.; Sun, Xiaoqing; Turanov, Anton A; Yang, Pengcheng; Yim, Sun Hee; Zhao, Xiang; Kasaikina, Marina V.; Stoletzki, Nina; Peng, Chunfang

    2011-01-01

    The naked mole rat (NMR, Heterocephalus glaber) is a strictly subterranean, extraordinarily long-lived eusocial mammal 1 . Although the size of a mouse, its maximum lifespan exceeds 30 years and makes this animal the longest living rodent. NMRs show negligible senescence, no age-related increase in mortality, and high fecundity until death 2 . In addition to delayed aging, NMRs are resistant to both spontaneous cancer and experimentally induced tumorigenesis 3,4 . NMRs pose a challenge to the...

  9. The reproductive biology of the Mashona mole - rat (\\kur{Fukomys darlingi}) from southern Malawi.

    OpenAIRE

    JERKOVIČOVÁ, Diana

    2010-01-01

    The population of the social Mashona mole - rat (Fukomys darlingi) from southern Malawi differs from the population from Zimbabwe in many aspects of its biology. In this study I have found remarkable differences also in the reproductive biology of these two populations. The most signifiant distinctions are double lenght of gestation and litters with more and larger pups in Malawian population. The analysis of reproductive and ecological parameters in bathyergids did not showed obvious differe...

  10. Simultaneous imaging of temperature and mole fraction using acetone planar laser-induced fluorescence

    Energy Technology Data Exchange (ETDEWEB)

    Thurber, M.C.; Hanson, R.K. [Stanford Univ., CA (United States). Dept. of Mechanical Engineering

    2001-01-01

    Imaging of concentration with acetone PLIF has become popular in mixing investigations. More recently, studies of the temperature dependences of acetone fluorescence have enabled quantitative imaging of temperature using single- or dual-wavelength excitation strategies. We present here the first demonstration of simultaneous imaging of temperature and mole fraction with acetone PLIF. Laser excitation is at 248 and 308 nm; the resulting fluorescence images are captured by an interline transfer CCD camera capable of acquiring two frames with a separation in time of as little as 500 ns. In addition to adding temperature imaging capability, this dual-wavelength approach enables mole fraction to be accurately measured in non-isothermal flows. Tests in a heated turbulent jet demonstrate the ability to record instantaneous mole fraction and temperature structure. The expected correspondence of the temperature and concentration fields is observed, and mean values of these quantities derived from image averaging show the expected radial and centerline profiles as the jet becomes fully developed. (orig.)

  11. Cutaneous and periodontal inputs to the cerebellum of the naked mole-rat (Heterocephalus glaber

    Directory of Open Access Journals (Sweden)

    Diana K Sarko

    2013-11-01

    Full Text Available The naked mole-rat (Heterocephalus glaber is a small fossorial rodent with specialized dentition that is reflected by the large cortical area dedicated to representation of the prominent incisors. Due to naked mole-rats’ behavioral reliance on the incisors for digging and for manipulating objects, as well as their ability to move the lower incisors independently, we hypothesized that expanded somatosensory representations of the incisors would be present within the cerebellum in order to accommodate a greater degree of proprioceptive, cutaneous, and periodontal input. Multiunit electrophysiological recordings targeting the ansiform lobule were used to investigate tactile inputs from receptive fields on the entire body with a focus on the incisors. Similar to other rodents, a fractured somatotopy appeared to be present with discrete representations of the same receptive fields repeated within each folium of the cerebellum. These findings confirm the presence of somatosensory inputs to a large area of the naked mole-rat cerebellum with particularly extensive representations of the lower incisors and mystacial vibrissae. We speculate that these extensive inputs facilitate processing of tactile cues as part of a sensorimotor integration network that optimizes how sensory stimuli are acquired through active exploration and in turn adjusts motor outputs (such as independent movement of the lower incisors. These results highlight the diverse sensory specializations and corresponding brain organizational schemes that have evolved in different mammals to facilitate exploration of and interaction with their environment.

  12. Structural, magnetic and microwave properties of barium hexaferrite thick films with different Fe/Ba mole ratio

    Energy Technology Data Exchange (ETDEWEB)

    Verma, Samiksha [School of Physics and Materials Science, Thapar University, Patiala 147004 (India); Dhawan, S.K. [Polymeric & Soft Materials Section, National Physical laboratory, New Delhi 119912 (India); Paesano, Andrea [Departamento de Fisica, Universidade Estadual de Maringá, Av. Colombo 5790, Maringá (Brazil); Pandey, O.P. [School of Physics and Materials Science, Thapar University, Patiala 147004 (India); Sharma, Puneet, E-mail: puneet.sharma@thapar.edu [School of Physics and Materials Science, Thapar University, Patiala 147004 (India)

    2015-12-15

    Barium hexaferrite (BaFe{sub 12}O{sub 19}) thick films (∼60 µm) with different BaO·xFe{sub 2}O{sub 3} mole ratio (x=5.0–6.0) were prepared by screen printing method. X-ray diffraction analysis confirmed the formation of single phase BaFe{sub 12}O{sub 19} (BaM). Preferential site occupation of Fe{sup 3+} ion at five different crystallographic sites, with varied mole ratio was measured by Mössbauer spectroscopy. Vacancy fraction found to be higher at 4f{sub 1}, 4f{sub 2} and 2b sites for mole ratio 5.5 and 5.0 respectively. Magnetic measurement shows that the magnetization (M) and magnetocrystalline anisotropy field (H{sub a}) depends upon mole ratio. M and H{sub a} are found to be maximum for mole ratio 5.5, while the coercivity (H{sub c}) remains constant. Reflection losses (R{sub L}) in the frequency range of 12–18 GHz were also studied. Present investigation demonstrates the effect of mole ratio on structural, magnetic and microwave absorption properties of BaM thick films for microwave device applications. - Highlights: • Single phase BaM thick films with different Fe/Ba mole ratio are prepared. • Site preference of Fe ion is estimated by Mössbauer spectroscopy. • Magnetization and magnetocrystalline ansisotropy is found maximum for 5.5 mole ratio. • Absorption frequency found to vary with the mole ratio.

  13. Adult neurogenesis in the hedgehog (Erinaceus concolor) and mole (Talpa europaea).

    Science.gov (United States)

    Bartkowska, K; Turlejski, K; Grabiec, M; Ghazaryan, A; Yavruoyan, E; Djavadian, R L

    2010-01-01

    We investigated adult neurogenesis in two species of mammals belonging to the superorder Laurasiatheria, the southern white-breasted hedgehog (order Erinaceomorpha, species Erinaceus concolor) from Armenia and the European mole (order Soricomorpha, species Talpa europaea) from Poland. Neurogenesis in the brain of these species was examined immunohistochemically, using the endogenous markers doublecortin (DCX) and Ki-67, which are highly conserved among species. We found that in both the hedgehog and mole, like in the majority of earlier investigated mammals, neurogenesis continues in the subventricular zone (SVZ) of the lateral ventricles and in the dentate gyrus (DG). In the DG of both species, DCX-expressing cells and Ki-67-labeled cells were present in the subgranular and granular layers. In the mole, a strong bundle of DCX-labeled processes, presumably axons of granule cells, was observed in the center of the hilus. Proliferating cells (expressing Ki-67) were identified in the SVZ of lateral ventricles of both species, but neuronal precursor cells (expressing DCX) were also observed in the olfactory bulb (OB). In both species, the vast majority of cells expressing DCX in the OB were granule cells with radially orientated dendrites, although some periglomerular cells surrounding the glomeruli were also labeled. In addition, this paper is the first to show DCX-labeled fibers in the anterior commissure of the hedgehog and mole. These fibers must be axons of new neurons making interhemispheric connections between the two OB or piriform (olfactory) cortices. DCX-expressing neurons were observed in the striatum and piriform cortex of both hedgehog and mole. We postulate that in both species a fraction of cells newly generated in the SVZ migrates along the rostral migratory stream to the piriform cortex. This pattern of migration resembles that of the 'second-wave neurons' generated during embryonal development of the neocortex rather than the pattern observed during

  14. MagAO: Status and Science

    CERN Document Server

    Morzinski, Katie M; Males, Jared R; Hinz, Phil M; Esposito, Simone; Riccardi, Armando; Briguglio, Runa; Follette, Katherine B; Pinna, Enrico; Puglisi, Alfio; Vezilj, Jennifer; Xompero, Marco; Wu, Ya-Lin

    2016-01-01

    "MagAO" is the adaptive optics instrument at the Magellan Clay telescope at Las Campanas Observatory, Chile. MagAO has a 585-actuator adaptive secondary mirror and 1000-Hz pyramid wavefront sensor, operating on natural guide stars from $R$-magnitudes of -1 to 15. MagAO has been in on-sky operation for 166 nights since installation in 2012. MagAO's unique capabilities are simultaneous imaging in the visible and infrared with VisAO and Clio, excellent performance at an excellent site, and a lean operations model. Science results from MagAO include the first ground-based CCD image of an exoplanet, demonstration of the first accreting protoplanets, discovery of a new wide-orbit exoplanet, and the first empirical bolometric luminosity of an exoplanet. We describe the status, report the AO performance, and summarize the science results. New developments reported here include color corrections on red guide stars for the wavefront sensor, a new field stop stage to facilitate VisAO imaging of extended sources; and eye...

  15. Investigation of the presence and antinociceptive function of muscarinic acetylcholine receptors in the African naked mole-rat (Heterocephalus glaber)

    DEFF Research Database (Denmark)

    Jørgensen, Kristine B.; Krogh-Jensen, Karen; Pickering, Darryl S;

    2016-01-01

    The present study investigated the cholinergic system in the African naked mole-rat (Heterocephalus glaber) with focus on the muscarinic acetylcholine receptor subtypes M1 and M4. The protein sequences for the subtypes m 1–5 of the naked mole-rat were compared to that of the house mouse (Mus...... musculus) using basic local alignment search tool (BLAST). The presence and function of M1 and M4 was investigated in vivo, using the formalin test with the muscarinic receptor agonists xanomeline and VU0152100. Spinal cord tissue from the naked mole-rat was used for receptor saturation binding studies...... with [3H]-N-methylscopolamine. The BLAST test revealed 95 % protein sequence homology showing the naked mole-rat to have the genetic potential to express all five muscarinic acetylcholine receptor subtypes. A significant reduction in pain behavior was demonstrated after administration of 8.4 mg...

  16. Clinical Usefulness of Immunohistochemical Staining of p57kip2 for the Differential Diagnosis of Complete Mole

    OpenAIRE

    Shigeru Sasaki; Yasushi Sasaki; Toshiaki Kunimura; Akihiko Sekizawa; Yoshihiro Kojima; Koichi Iino

    2015-01-01

    Objective. Can polymer-based immunohistochemical staining of p57kip2 replace DNA analysis as an inexpensive means of differentiating complete mole from partial mole or hydropic abortion? Methods and Materials. Original paraffin-embedded tissue blocks from 14 equivocal cases were turned over to our laboratory and examined by immunohistochemical staining of p57kip2. Results. Four of the 14 cases showed clearly negative nuclear staining in cytotrophoblasts and villous stromal cells: these result...

  17. Two-dimensional electron gas (2DEG) mobility affected by the in mole fraction fluctuation in InxAl1-xN/GaN heterostructures

    Science.gov (United States)

    Liu, Guipeng; Zhang, Jinfeng; Lu, Kunyi; Chen, Wenjie; Tian, Yonghui; Yang, Jianhong

    2016-09-01

    In an InxAl1-xN/GaN heterostructure, we have studied the mobility limited by the In mole fraction fluctuation scattering. The In mole fraction fluctuation characterizes the quality of the InxAl1-xN material with two parameters, one is the mole fraction fluctuation δx and the other is its lateral s Λ. Similar to a roughness scattering, for a fixed mole fraction x, the mobility limited by the In mole fraction fluctuation initially decreases with Λ increasing, reaches a minimum at a certain value of Λ and then increases.

  18. Clinical Usefulness of Immunohistochemical Staining of p57kip2 for the Differential Diagnosis of Complete Mole

    Directory of Open Access Journals (Sweden)

    Shigeru Sasaki

    2015-01-01

    Full Text Available Objective. Can polymer-based immunohistochemical staining of p57kip2 replace DNA analysis as an inexpensive means of differentiating complete mole from partial mole or hydropic abortion? Methods and Materials. Original paraffin-embedded tissue blocks from 14 equivocal cases were turned over to our laboratory and examined by immunohistochemical staining of p57kip2. Results. Four of the 14 cases showed clearly negative nuclear staining in cytotrophoblasts and villous stromal cells: these results were fully concordant with the control staining. The remaining 10 cases showed apparently positive staining in cytotrophoblasts and villous stromal cells. Without DNA analysis we are able to clearly differentiate the 4 cases of complete mole among the 14 equivocal cases. During follow-up, secondary low-risk gestational trophoblastic neoplasia (GTN developed in 1 of the 4 cases of complete mole: the GTN was treated by single-agent chemotherapy. No subsequent changes were observed during follow-up in the other cases. Conclusion. Polymer-based immunohistochemical staining of p57kip2 (paternally imprinted gene, expressed from maternal allele is a very effective method that can be used to differentiate androgenetic complete mole from partial mole and hydropic abortion. We might be able to avoid the cost of DNA analysis.

  19. Mechanisms regulating proteostasis are involved in sympatric speciation of the blind mole rat, Spalax galili.

    Science.gov (United States)

    Rodriguez, Karl A; Li, Kexin; Nevo, Eviatar; Buffenstein, Rochelle

    2016-01-01

    Genome-wide analysis demonstrates extensive genomic adaptive complexes involved in sympatric speciation between blind mole rats (Spalax galili) in abutting populations living in basalt and chalk soils. Among the gene ontology (GO) enrichment, musculature and metabolism stood out in basalt dwellers while nutrition and neurogenetics were highlighted in chalk residents. Measurements of mechanisms regulating protein homeostasis inspired by these GO terms suggest that at the proteomic level there is also a habitat/soil-type driven divergence with the basalt residents exhibiting higher proteasome activity whereas elevated levels of markers of autophagy are evident in the chalk inhabitants.

  20. Ultrasound imaging of partial hydatidiform mole in the second trimester of pregnancy

    International Nuclear Information System (INIS)

    The case report of a 27 year-old patient with 18 weeks gestation, admitted to the Obstetrics Department of 'Mariana Grajales Coello' Provincial Gynecology and Obstetrics Hospital of Santiago de Cuba due to high blood pressure, cephalea and pain in lower abdomen is described. Additional tests confirmed a partial hydatidiform mole, so that uterine curettage was performed and small fragments of endometrial stroma were removed for pathological study. Outpatient medical monitoring was recommended and the patient had an appointment at 21 days for controlling and evaluating her general state

  1. The effect of carbon mole ratio on the fabrication of silicon carbide

    OpenAIRE

    Sutham Niyomwas

    2008-01-01

    Silicon Carbide (SiC) particles were synthesized by self-propagating high temperature synthesis (SHS) from a powder mixture of SiO2-C-Mg. The reaction was carried out in a SHS reactor under static argon gas at a pressure of 0.5 MPa. The standard Gibbs energy minimization method was used to calculate the equilibrium composition of the reacting species. The effects of carbon mole ratio on the precursor mixture (C/SiO2/Mg: 1/1/2 to 3/1/2) and on the SiC conversion were investigated using X-ray d...

  2. High accuracy measurements of dry mole fractions of carbon dioxide and methane in humid air

    OpenAIRE

    Rella, C. W.; H Chen; A. E. Andrews; A. Filges; C. Gerbig; Hatakka, J.; A. Karion; N. L. Miles; Richardson, S. J.; M. Steinbacher; C. Sweeney; Wastine, B.; Zellweger, C.

    2012-01-01

    Traditional techniques for measuring the mole fractions of greenhouse gas in the well-mixed atmosphere have required extremely dry sample gas streams (dew point < −25 °C) to achieve the inter-laboratory compatibility goals set forth by the Global Atmospheric Watch program of the World Meteorological Organization (WMO/GAW) for carbon dioxide (±0.1 ppm) and methane (±2 ppb). Drying the sample gas to low levels of water vapor can be expensive, time-consuming, and/or problematic, especial...

  3. Hearing in mole crickets (Orthoptera: Gryllotalpidae) at sonic and ultrasonic frequencies.

    Science.gov (United States)

    Mason, A C; Forrest, T G; Hoy, R R

    1998-06-01

    We have studied auditory responses in two species of mole cricket (Scapteriscus borellii and S. abbreviatus) to determine (1) whether they show sensitivity to ultrasound, (2) whether their hearing (at both low and high frequencies) is based on the same neural circuitry as that of true crickets, and (3) whether ultrasound sensitivity in different mole cricket species varies with their ability to fly. S. borellii are sensitive to ultrasonic frequencies. There is evidence of a segregation of frequency bands in prothoracic auditory neurons. There are two pairs of omega neurons (ONs) with similar morphology to ON1 of true crickets. The two pairs of ONs differ in tuning. One pair has two sensitivity peaks: at the frequency of the calling song of this species (3 kHz), and in the ultrasonic range (25 kHz). The other pair lacks the high-frequency sensitivity and responds exclusively to frequencies in the range of the species song. These two types are not morphologically distinguishable. In S. abbreviatus, only one class of ON was found. S. abbreviatus ONs are narrowly tuned to the frequency of the species' calls. A T-neuron had the best ultrasonic frequency sensitivity in S. borellii. This cell showed a broad tuning to ultrasonic frequencies and was inhibited by low-frequency stimuli. A morphologically similar neuron was also recorded in S. abbreviatus, but lacked the high-frequency sensitivity peak of that in S. borellii. We also assessed the responses of flying S. borellii to ultrasound using field playbacks to free-flying animals. The attractiveness of broadcast calling song was diminished by the addition of an ultrasound signal, indicating that S. borellii avoid high-frequency sound. The results indicate that mole crickets process low-frequency auditory stimuli using mechanisms similar to those of true crickets. They show a negative behavioural response to high-frequency stimuli, as do true crickets, but the organization of ultrasound-sensitive auditory circuitry in

  4. Adaptations to a Subterranean Environment and Longevity Revealed by the Analysis of Mole Rat Genomes

    Directory of Open Access Journals (Sweden)

    Xiaodong Fang

    2014-09-01

    Full Text Available Subterranean mammals spend their lives in dark, unventilated environments that are rich in carbon dioxide and ammonia and low in oxygen. Many of these animals are also long-lived and exhibit reduced aging-associated diseases, such as neurodegenerative disorders and cancer. We sequenced the genome of the Damaraland mole rat (DMR, Fukomys damarensis and improved the genome assembly of the naked mole rat (NMR, Heterocephalus glaber. Comparative genome analyses, along with the transcriptomes of related subterranean rodents, revealed candidate molecular adaptations for subterranean life and longevity, including a divergent insulin peptide, expression of oxygen-carrying globins in the brain, prevention of high CO2-induced pain perception, and enhanced ammonia detoxification. Juxtaposition of the genomes of DMR and other more conventional animals with the genome of NMR revealed several truly exceptional NMR features: unusual thermogenesis, an aberrant melatonin system, pain insensitivity, and unique processing of 28S rRNA. Together, these genomes and transcriptomes extend our understanding of subterranean adaptations, stress resistance, and longevity.

  5. High accuracy measurements of dry mole fractions of carbon dioxide and methane in humid air

    Directory of Open Access Journals (Sweden)

    C. W. Rella

    2013-03-01

    Full Text Available Traditional techniques for measuring the mole fractions of greenhouse gases in the well-mixed atmosphere have required dry sample gas streams (dew point inter-laboratory compatibility goals (WMO, 2011a without drying the sample gas. In this paper, we present laboratory methodology for empirically deriving the water vapour correction factors, and we summarise a series of in-situ validation experiments comparing the measurements in humid gas streams to well-characterised dry-gas measurements. By using the manufacturer-supplied correction factors, the dry-mole fraction measurements have been demonstrated to be well within the GAW compatibility goals up to a water vapour concentration of at least 1%. By determining the correction factors for individual instruments once at the start of life, this water vapour concentration range can be extended to at least 2% over the life of the instrument, and if the correction factors are determined periodically over time, the evidence suggests that this range can be extended up to and even above 4% water vapour concentrations.

  6. Peripheral administration of oxytocin increases social affiliation in the naked mole-rat (Heterocephalus glaber).

    Science.gov (United States)

    Mooney, Skyler J; Douglas, Natasha R; Holmes, Melissa M

    2014-04-01

    The neuropeptide oxytocin regulates a wide variety of social behaviors across diverse species. However, the types of behaviors that are influenced by this hormone are constrained by the species in question and the social organization that a particular species exhibits. Therefore, the present experiments investigated behaviors regulated by oxytocin in a eusocial mammalian species by using the naked mole-rat (Heterocephalus glaber). In Experiment 1, adult non-breeding mole-rats were given intraperitoneal injections of either oxytocin (1mg/kg or 10mg/kg) or saline on alternate days. Animals were then returned to their colony and behavior was recorded for minutes 15-30 post-injection. Both doses of oxytocin increased huddling behavior during this time period. In Experiment 2, animals received intraperitoneal injections of either oxytocin (1mg/kg), an oxytocin-receptor antagonist (0.1mg/kg), a cocktail of oxytocin and the antagonist, or saline across 4 testing days in a counterbalanced design. Animals were placed in either a 2-chamber arena with a familiar conspecific or in a small chamber with 1week old pups from their home colony and behaviors were recorded for minutes 15-30 post-injection. Oxytocin increased investigation of, and time spent in close proximity to, a familiar conspecific; these effects were blocked by the oxytocin antagonist. No effects were seen on pup-directed behavior. These data suggest that oxytocin is capable of modulating affiliative-like behavior in this eusocial species.

  7. Resonant Spin-Flavor Conversion of Supernova Neutrinos: Dependence on Electron Mole Fraction

    CERN Document Server

    Yoshida, T; Kimura, K; Yokomakura, H; Kawagoe, S; Kajino, T

    2009-01-01

    Detailed dependence of resonant spin-flavor (RSF) conversion of supernova neutrinos on electron mole fraction Ye is investigated. Supernova explosion forms a hot-bubble and neutrino-driven wind region of which electron mole fraction exceeds 0.5 in several seconds after the core collapse. When a higher resonance of the RSF conversion is located in the innermost region, flavor change of the neutrinos strongly depends on the sign of 1-2Ye. At an adiabatic high RSF resonance the flavor conversion of bar{nu}_e -> nu_{mu,tau} occurs in Ye 0.5 and inverted mass hierarchy. In other cases of Ye values and mass hierarchies, the conversion of nu_e -> bar{nu}_{mu,tau} occurs. The final bar{nu}_e spectrum is evaluated in the cases of Ye 0.5 taking account of the RSF conversion. Based on the obtained result, time variation of the event number ratios of low bar{nu}_e energy to high bar{nu}_e energy is discussed. In normal mass hierarchy, an enhancement of the event ratio should be seen in the period when the electron frac...

  8. Acheivement of Nano-Scale SiGe Layer with Discrete Ge Mole Fraction Profile Using Batch-Type HVCVD

    Institute of Scientific and Technical Information of China (English)

    Gon-sub Lee; Tae-hun Shim; Jea-gun Park

    2004-01-01

    The strained Si grown on the relaxed SiGe-on-insulator C-MOSFET's is a promising device for the future system LSI devices with the design rule of sub-micron. The achievement of the discrete Ge mole fraction in the SiGe layer is a key engineering in low-temperature SiGe epitaxial growth using HVCVD. The pre-flow of GeH4 gas enhanced the Ge mole fraction and SiGe layer thickness. In addition, the Ge mole fraction and SiGe layer thickness increases with the gas ratio of GeH4/SiH4 + GeH4, process temperature, and gas flow time. However, the haze was produced if the Ge mole fraction is above 22wt%. The discrete-like Ge mole fraction with 22 wt% in 10 nm SiGe layer was obtained by the pre-flow of GeH4 for 10 s, the mixture gas ratio of GeH4/SiH4 + GeH4 of 67%, and the gas flow time for 150 s at the process temperature of 550 C.

  9. Estimating regional methane surface fluxes: the relative importance of surface and GOSAT mole fraction measurements

    Directory of Open Access Journals (Sweden)

    A. Fraser

    2013-06-01

    Full Text Available We use an ensemble Kalman filter (EnKF, together with the GEOS-Chem chemistry transport model, to estimate regional monthly methane (CH4 fluxes for the period June 2009–December 2010 using proxy dry-air column-averaged mole fractions of methane (XCH4 from GOSAT (Greenhouse gases Observing SATellite and/or NOAA ESRL (Earth System Research Laboratory and CSIRO GASLAB (Global Atmospheric Sampling Laboratory CH4 surface mole fraction measurements. Global posterior estimates using GOSAT and/or surface measurements are between 510–516 Tg yr−1, which is less than, though within the uncertainty of, the prior global flux of 529 ± 25 Tg yr−1. We find larger differences between regional prior and posterior fluxes, with the largest changes in monthly emissions (75 Tg yr−1 occurring in Temperate Eurasia. In non-boreal regions the error reductions for inversions using the GOSAT data are at least three times larger (up to 45% than if only surface data are assimilated, a reflection of the greater spatial coverage of GOSAT, with the two exceptions of latitudes >60° associated with a data filter and over Europe where the surface network adequately describes fluxes on our model spatial and temporal grid. We use CarbonTracker and GEOS-Chem XCO2 model output to investigate model error on quantifying proxy GOSAT XCH4 (involving model XCO2 and inferring methane flux estimates from surface mole fraction data and show similar resulting fluxes, with differences reflecting initial differences in the proxy value. Using a series of observing system simulation experiments (OSSEs we characterize the posterior flux error introduced by non-uniform atmospheric sampling by GOSAT. We show that clear-sky measurements can theoretically reproduce fluxes within 10% of true values, with the exception of tropical regions where, due to a large seasonal cycle in the number of measurements because of clouds and aerosols, fluxes are within 15% of true fluxes. We evaluate our

  10. Antioxidant activity and prevention of pork meat lipid oxidation using traditional Mexican condiments (pasilla dry pepper, achiote, and mole sauce

    Directory of Open Access Journals (Sweden)

    Emilio Alvarez-Parrilla

    2014-06-01

    Full Text Available Considering the extensive use of hot peppers and spicy sauces in the Mexican cuisine, in the present paper, three widely consumed Mexican condiments (mole sauce, achiote, and pasilla hot pepper were analyzed for their total phenols, flavonoids and proanthocyanidins, antioxidant activity, and protective effect against lipid oxidation in chopped pork meat. All samples were extracted first with methanol and then with acetone, and the extracts were compared. Pasilla pepper showed the highest phenolic and flavonoid content in both solvents, followed by mole and achiote. Achiote showed the highest proanthocyanidin concentration. All samples showed high antioxidant activity, and good correlations with phenolic compounds and flavonoids, while no correlation was observed in the case of condensed tannins. Mole sauce methanolic extract showed the highest inhibition of pork meat oxidation, followed by pasilla pepper, and finally achiote paste extracts. These results suggest that these condiments are useful to prevent meat lipid oxidation during storage.

  11. Current transport mechanism in graphene/AlGaN/GaN heterostructures with various Al mole fractions

    Science.gov (United States)

    Pandit, Bhishma; Seo, Tae Hoon; Ryu, Beo Deul; Cho, Jaehee

    2016-06-01

    The current transport mechanism of graphene formed on AlxGa1-xN/GaN heterostructures with various Al mole fractions (x = 0.15, 0.20, 0.30, and 0.40) is investigated. The current-voltage measurement from graphene to AlGaN/GaN shows an excellent rectifying property. The extracted Schottky barrier height of the graphene/AlGaN/GaN contacts increases with the Al mole fraction in AlGaN. However, the current transport mechanism deviates from the Schottky-Mott theory owing to the deterioration of AlGaN crystal quality at high Al mole fractions confirmed by reverse leakage current measurement.

  12. Ultrastructural effects of ultraviolet C radiation on the stratum basale of mole rats epidermis

    Directory of Open Access Journals (Sweden)

    Mustafa Yel

    2014-10-01

    Full Text Available The ultrastructure of the epidermis of mole rats (Spalax leucodon was studied after irradiation with ultraviolet (UV light (λmax = 254 nm; 0.00147 J cm−2 s−1; for periods of 52, 112 and 168 h by using transmission electron microscope (TEM. After irradiation, Vacuolation in cytoplasm and mitochondria, and wrinkled nucleus were found in the stratum basal cells. Also, pathological aggregations of tonofilaments are formed in the desmosomes in these cells. These findings clearly demonstrated the harmful effects of ultraviolet C radiation on the stratum basale. The degree of pathological changes occurred depending on exposure time and radiation dosage applied.

  13. Whack-A-Mole Model: Towards unified description of biological effect caused by radiation-exposure

    CERN Document Server

    Manabe, Yuichiro; Tsunoyama, Yuichi; Nakajima, Hiroo; Nakamura, Issei; Bando, Masako

    2014-01-01

    We present a novel model to estimate biological effects caused by artificial radiation exposure, Whack-a-mole (WAM) model. It is important to take account of the recovery effects during the time course of the cellular reactions. The inclusion of the dose-rate dependence is essential in the risk estimation of low dose radiation, while nearly all the existing theoretical models relies on the total dose dependence only. By analyzing the experimental data of the relation between the radiation dose and the induced mutation frequency of 5 organisms, mouse, drosophila, chrysanthemum, maize and tradescantia, we found that all the data can be reproduced by WAM model. Most remarkably, a scaling function, which is derived from WAM model, consistently accounts for the observed mutation frequencies of 5 organisms. This is the first rationale to account for the dose rate dependence as well as to give a unified understanding of a general feature of organisms.

  14. The effect of carbon mole ratio on the fabrication of silicon carbide

    Directory of Open Access Journals (Sweden)

    Sutham Niyomwas

    2008-03-01

    Full Text Available Silicon Carbide (SiC particles were synthesized by self-propagating high temperature synthesis (SHS from a powder mixture of SiO2-C-Mg. The reaction was carried out in a SHS reactor under static argon gas at a pressure of 0.5 MPa. The standard Gibbs energy minimization method was used to calculate the equilibrium composition of the reacting species. The effects of carbon mole ratio on the precursor mixture (C/SiO2/Mg: 1/1/2 to 3/1/2 and on the SiC conversion were investigated using X-ray diffraction and scanning electron microscope technique. The as-synthesized products of SiC-MgO powders were leached with 0.1M HCl acid solution to obtain the SiC particles.

  15. Ovarian hyperstimulation syndrome in a spontaneous pregnancy with invasive mole: report of a case.

    Science.gov (United States)

    Rachad, Myriam; Chaara, Hikmat; Zahra Fdili, Fatim; Bouguern, Hakima; Melhouf, Abdilah

    2011-01-01

    It is known that most cases of Ovarian Hyperstimulation Syndrome (OHSS) are associated with the therapies for ovulation induction. However, OHSS may rarely be associated with a spontaneous ovulatory cycle, usually in the case of multiple gestations, hypothyroidism or polycystic ovary syndrome. We report a case of severe OHSS in spontaneous pregnancy with invasive mole in a 34 years old woman. The clinical picture showed abdominal pain, massive ascites, nausea, dyspnea and amenorrhea. After imaging examinations and laboratory tests, the diagnosis was established. The patient was managed expectantly with no complications. Although spontaneous ovarian hyperstimulation is a rare entity, it is important that the physician recognizes this condition. Prompt diagnosis and successful management is likely to avoid serious complications, which may develop rapidly. PMID:22355432

  16. Effect of Temperature and Mole Ratio on the Synthesis Yield of Rhenium-Tetrofosmin

    Directory of Open Access Journals (Sweden)

    Widyastuti

    2015-08-01

    Full Text Available Technetium-99m (99mTc tetrofosmin is widely used in nuclear medicine as a diagnostic agent for myocardial perfusion and as a tumor imaging agent. As a parenteral preparation it requires an evaluation of its pharmacokinetics and stability in-vivo. Since 99mTc has a short half-life and is only available in very low concentrations, it is impossible to characterize its chemical properties and presence in the body. Due to this reason, only technetium-99 (T1/2 = 5 × 105 years, which is available in macro quantities, or natural rhenium can be used for this purpose. In this study rhenium-188 (188Re tetrofosmin will be synthesized and applied, because non-radioactive Re can be easily obtained. Synthesis and radiochemical purity analysis of carrier-added 188Re-tetrofosmin were carried out as a model to study the in-vivo stability of technetium-99m tetrofosmin. Rhenium-188 was used as a tracer to identify the formation of rhenium tetrofosmin. Rhenium gluconate was synthesized first prior to the formation of rhenium tetrofosmin. The quality of labeling for both rhenium gluconate and rhenium tetrofosmin was analyzed using paper- and thin-layer chromatography, respectively. Rhenium gluconate can be synthesized with high labeling yield within 1 hour, whereas rhenium tetrofosmin was synthesized both in room temperature and in an elevated temperature with various tetrofosmin-to-rhenium mole ratios.The results showed that heating at 95oC led to a higher yield of more than 90% within 30 minutes. Rhenium tetrofosmin could be produced in high radiochemical purity using an excess of tetrofosmin with mole ratio of 2000. It is concluded that rhenium tetrofosmin could be synthesized through the formation of rhenium gluconate, and a higher yield could be obtained in a shorter time by heating process.

  17. Transcriptome, genetic editing, and microRNA divergence substantiate sympatric speciation of blind mole rat, Spalax.

    Science.gov (United States)

    Li, Kexin; Wang, Liuyang; Knisbacher, Binyamin A; Xu, Qinqin; Levanon, Erez Y; Wang, Huihua; Frenkel-Morgenstern, Milana; Tagore, Satabdi; Fang, Xiaodong; Bazak, Lily; Buchumenski, Ilana; Zhao, Yang; Lövy, Matěj; Li, Xiangfeng; Han, Lijuan; Frenkel, Zeev; Beiles, Avigdor; Cao, Yi Bin; Wang, Zhen Long; Nevo, Eviatar

    2016-07-01

    Incipient sympatric speciation in blind mole rat, Spalax galili, in Israel, caused by sharp ecological divergence of abutting chalk-basalt ecologies, has been proposed previously based on mitochondrial and whole-genome nuclear DNA. Here, we present new evidence, including transcriptome, DNA editing, microRNA, and codon usage, substantiating earlier evidence for adaptive divergence in the abutting chalk and basalt populations. Genetic divergence, based on the previous and new evidence, is ongoing despite restricted gene flow between the two populations. The principal component analysis, neighbor-joining tree, and genetic structure analysis of the transcriptome clearly show the clustered divergent two mole rat populations. Gene-expression level analysis indicates that the population transcriptome divergence is displayed not only by soil divergence but also by sex. Gene ontology enrichment of the differentially expressed genes from the two abutting soil populations highlights reproductive isolation. Alternative splicing variation of the two abutting soil populations displays two distinct splicing patterns. L-shaped FST distribution indicates that the two populations have undergone divergence with gene flow. Transcriptome divergent genes highlight neurogenetics and nutrition characterizing the chalk population, and energetics, metabolism, musculature, and sensory perception characterizing the abutting basalt population. Remarkably, microRNAs also display divergence between the two populations. The GC content is significantly higher in chalk than in basalt, and stress-response genes mostly prefer nonoptimal codons. The multiple lines of evidence of ecological-genomic and genetic divergence highlight that natural selection overrules the gene flow between the two abutting populations, substantiating the sharp ecological chalk-basalt divergence driving sympatric speciation.

  18. Micro- and macrogeographical genetic structure of colonies of naked mole-rats Heterocephalus glaber.

    Science.gov (United States)

    Faulkes, C G; Abbott, D H; O'Brien, H P; Lau, L; Roy, M R; Wayne, R K; Bruford, M W

    1997-07-01

    Patterns of genetic structure in eusocial naked mole-rat populations were quantified within and among geographically distant populations using multilocus DNA fingerprinting and mitochondrial DNA (mtDNA) sequence analysis. Individuals within colonies were genetically almost monomorphic, sharing the same mtDNA control region haplotype and having coefficients of band sharing estimated from DNA fingerprints ranging from 0.93 to 0.99. Family analysis of a hybrid captive colony of naked mole-rats with increased levels of genetic variability using multilocus DNA fingerprinting gave results consistent with Mendelian inheritance, and has revealed for the first time that multiple paternity can occur. In a survey of wild colonies from Ethiopia, Somalia and locations in northern and southern Kenya, we have examined mtDNA control region sequence variation in 42 individuals from 15 colonies, and together with multilocus DNA fingerprinting and mtDNA cytochrome-b sequence analysis in selected individuals have shown that these populations show considerable genetic divergence. Most of the variance in sequence divergence was found to be between geographical locations (phi ct = 0.68) and there was a significant correlation between sequence divergence and geographical separation of haplotypes. Six colonies from Mtito Andei in southern Kenya shared the same control region haplotype, suggesting a recent common maternal ancestor. In contrast, out of four colonies at Lerata in north Kenya, three haplotypes were identified, and phylogenetic analysis suggests that this area may be a zone where two distinct lineages are in close proximity. Genetic distances were maximal between Ethiopian and southern Kenyan populations at 5.8% for cytochrome-b, and are approaching interspecific values seen between other Bathyergids.

  19. Adaptation of pelage color and pigment variations in Israeli subterranean blind mole rats, Spalax ehrenbergi [corrected].

    Directory of Open Access Journals (Sweden)

    Natarajan Singaravelan

    Full Text Available BACKGROUND: Concealing coloration in rodents is well established. However, only a few studies examined how soil color, pelage color, hair-melanin content, and genetics (i.e., the causal chain synergize to configure it. This study investigates the causal chain of dorsal coloration in Israeli subterranean blind mole rats, Spalax ehrenbergi. METHODS: We examined pelage coloration of 128 adult animals from 11 populations belonging to four species of Spalax ehrenbergi superspecies (Spalax galili, Spalax golani, Spalax carmeli, and Spalax judaei and the corresponding coloration of soil samples from the collection sites using a digital colorimeter. Additionally, we quantified hair-melanin contents of 67 animals using HPLC and sequenced the MC1R gene in 68 individuals from all four mole rat species. RESULTS: Due to high variability of soil colors, the correlation between soil and pelage color coordinates was weak and significant only between soil hue and pelage lightness. Multiple stepwise forward regression revealed that soil lightness was significantly associated with all pelage color variables. Pelage color lightness among the four species increased with the higher southward aridity in accordance to Gloger's rule (darker in humid habitats and lighter in arid habitats. Darker and lighter pelage colors are associated with darker basalt and terra rossa, and lighter rendzina soils, respectively. Despite soil lightness varying significantly, pelage lightness and eumelanin converged among populations living in similar soil types. Partial sequencing of the MC1R gene identified three allelic variants, two of which were predominant in northern species (S. galili and S. golani, and the third was exclusive to southern species (S. carmeli and S. judaei, which might have caused the differences found in pheomelanin/eumelanin ratio. CONCLUSION/SIGNIFICANCE: Darker dorsal pelage in darker basalt and terra rossa soils in the north and lighter pelage in rendzina and

  20. High accuracy measurements of dry mole fractions of carbon dioxide and methane in humid air

    Directory of Open Access Journals (Sweden)

    C. W. Rella

    2012-08-01

    Full Text Available Traditional techniques for measuring the mole fractions of greenhouse gas in the well-mixed atmosphere have required extremely dry sample gas streams (dew point < −25 °C to achieve the inter-laboratory compatibility goals set forth by the Global Atmospheric Watch program of the World Meteorological Organization (WMO/GAW for carbon dioxide (±0.1 ppm and methane (±2 ppb. Drying the sample gas to low levels of water vapor can be expensive, time-consuming, and/or problematic, especially at remote sites where access is difficult. Recent advances in optical measurement techniques, in particular Cavity Ring Down Spectroscopy (CRDS, have led to the development of highly stable and precise greenhouse gas analyzers capable of highly accurate measurements of carbon dioxide, methane, and water vapor. Unlike many older technologies, which can suffer from significant uncorrected interference from water vapor, these instruments permit for the first time accurate and precise greenhouse gas measurements that can meet the WMO/GAW inter-laboratory compatibility goals without drying the sample gas. In this paper, we present laboratory methodology for empirically deriving the water vapor correction factors, and we summarize a series of in-situ validation experiments comparing the measurements in humid gas streams to well-characterized dry-gas measurements. By using the manufacturer-supplied correction factors, the dry-mole fraction measurements have been demonstrated to be well within the GAW compatibility goals up to at least 1% water vapor. By determining the correction factors for individual instruments once at the start of life, this range can be extended to at least 2% over the life of the instrument, and if the correction factors are determined periodically over time, the evidence suggests that this range can be extended above 4%.

  1. Gis-approach for variability assessment of soil electric conductivity under pedoturbation activity of mole rat (Spalax microphthalmus

    Directory of Open Access Journals (Sweden)

    T. М. Konovalova

    2010-06-01

    Full Text Available The results of the investigation of the impact of the mole rat’s activity on soil electric conductivity have been presented. GIS-technology have been shown to be effective for assessment of the pedoturbation activity effect on the soil surface heterogeneity formation. Method of the one-dimension spatial coordinated array transformation into matrix form has been proposed for following multidimension statistic analysis application. The quantity estimation of the mole rats role in formation of the habitat nanorelief-level diversity has been obtained by means of indexes of the landscape complexity and diversity.

  2. Revis\\~ao da Constru\\c{c}\\~ao de Modelos Supersim\\'etricos

    CERN Document Server

    Rodríguez, M C

    2001-01-01

    Foi com base neste estudo que fizemos a constru\\c{c}\\~ao da vers\\~ao supersim\\'etrica dos modelos de simetria $SU(3)_{C} \\otimes SU(3)_{L} \\otimes U(1)_{N}$ \\cite{susy331}, apresentado no final da minha tese de doutorado \\cite{mcr1}. Bem como dos estudos fenomenol\\'ogicos subsequente \\cite{mcr}.

  3. Into the Blue: AO Science with MagAO in the Visible

    CERN Document Server

    Close, Laird M; Follette, Katherine B; Hinz, Phil; Morzinski, Katie M; Wu, Ya-Lin; Kopon, Derek; Riccardi, Armando; Esposito, Simone; Puglisi, Alfio; Pinna, Enrico; Xompero, Marco; Briguglio, Runa; Quiros-Pacheco, Fernando

    2014-01-01

    We review astronomical results in the visible ({\\lambda}<1{\\mu}m) with adaptive optics. Other than a brief period in the early 1990s, there has been little astronomical science done in the visible with AO until recently. The most productive visible AO system to date is our 6.5m Magellan telescope AO system (MagAO). MagAO is an advanced Adaptive Secondary system at the Magellan 6.5m in Chile. This secondary has 585 actuators with < 1 msec response times (0.7 ms typically). We use a pyramid wavefront sensor. The relatively small actuator pitch (~23 cm/subap) allows moderate Strehls to be obtained in the visible (0.63-1.05 microns). We use a CCD AO science camera called "VisAO". On-sky long exposures (60s) achieve <30mas resolutions, 30% Strehls at 0.62 microns (r') with the VisAO camera in 0.5" seeing with bright R < 8 mag stars. These relatively high visible wavelength Strehls are made possible by our powerful combination of a next generation ASM and a Pyramid WFS with 378 controlled modes and 1000...

  4. Efeito da data de sementeira na produtividade de trigo mole (Triticum Aestivum L. em condições mediterrânicas Effect of the sowing date on bread wheat (Triticum Aestivum L. productivity under mediterranean conditions

    Directory of Open Access Journals (Sweden)

    José Manuel Godinho Calado

    2008-01-01

    Full Text Available A data de sementeira do trigo mole exerce uma influência relevante no crescimento e desenvolvimento da cultura, condicionando a sua produtividade. O seu efeito é, especial-mente, importante sob condições mediterrânicas. Por isso, neste trabalho procurou-se verificar a influência da data de sementeira no rendimento do trigo mole, a partir de um ensaio de quinze genótipos semeados em datas diferentes durante cinco anos (1994/95 a 1999/00 na região Alentejo. Com base na análise dos resultados conclui-se que a variação da época de sementeira em aproximadamente um mês, desde o fim de Outubro até ao fim de Novembro, pode permitir rendimentos viáveis do trigo mole nas zonas cerealíferas mediterrânicas, particularmente na região Alentejo. Todavia, as produções mais altas tendem a ser obtidas quando a sementeira é efectuada na primeira quinzena de Novembro. Ao avançar a sementeira para o mês de Dezembro decresce a produtividade e, em consequência, diminui a viabilidade da cultura.The sowing date of bread wheat has a great influence on the growth and development of the crop and its productivity, especially under Mediterranean conditions. This paper presents the results of trials conducted in the Alentejo region that studied the performance of fifteen wheat genotypes sown at different dates, repeated over 5 years (1994/95 to 1999/00. Despite a great variability between years, the results indicate that a satisfactory wheat productivity in the Alentejo can be obtained with sowing dates ranging from end of October until the end of November. Nonetheless, sowing dates in the first half of November tend to provide higher grain yields. Moving the sowing date into December results in reduced grain yields, thus compromising the economic viability of wheat growing.

  5. Into the blue: AO science with MagAO in the visible

    Science.gov (United States)

    Close, Laird M.; Males, Jared R.; Follette, Katherine B.; Hinz, Phil; Morzinski, Katie; Wu, Ya-Lin; Kopon, Derek; Riccardi, Armando; Esposito, Simone; Puglisi, Alfio; Pinna, Enrico; Xompero, Marco; Briguglio, Runa; Quiros-Pacheco, Fernando

    2014-08-01

    We review astronomical results in the visible (λresponse times (0.7 ms typically). We use a pyramid wavefront sensor. The relatively small actuator pitch (~23 cm/subap) allows moderate Strehls to be obtained in the visible (0.63-1.05 microns). We use a CCD AO science camera called "VisAO". On-sky long exposures (60s) achieve Pyramid WFS with 378 controlled modes and 1000 Hz loop frequency. We'll review the key steps to having good performance in the visible and review the exciting new AO visible science opportunities and refereed publications in both broad-band (r,i,z,Y) and at Halpha for exoplanets, protoplanetary disks, young stars, and emission line jets. These examples highlight the power of visible AO to probe circumstellar regions/spatial resolutions that would otherwise require much larger diameter telescopes with classical infrared AO cameras.

  6. ECOPERSONALISMO E DIREITO AO MEIO AMBIENTE

    OpenAIRE

    2008-01-01

    O objetivo do presente artigo consiste em refletir brevemente sobre as conseqüências, no âmbito do direito ao meio ambiente, das diferentes concepções sobre a relação entre o ser humano e a natureza, isto é, o modelo tecnocrático, o biologista e o ecológico-personalista

  7. Illustrated key for the identification of the mole crabs (Decapoda, Anomura, Hippoidea of the Cuban sea waters

    Directory of Open Access Journals (Sweden)

    Rogelio Lalana

    2013-09-01

    Full Text Available An illustrated key to the identification of the families, four genera and 5 species, as well as a possible additional genus, of the Cuban waters mole crabs (Anomura, Hippoidea are presented. One of these is a new record for Cuba. The general and Cuban distribution of each species and their habitat, are also given.

  8. Pigmentary Markers in Danes - Associations with Quantitative Skin Colour, Nevi Count, Familial Atypical Multiple-Mole, and Melanoma Syndrome

    DEFF Research Database (Denmark)

    Johansen, Peter; Andersen, Jeppe Dyrberg; Madsen, Linnea Nørgård;

    2016-01-01

    multiple mole and melanoma (FAMMM) syndrome. We typed 32 pigmentary SNP markers and sequenced MC1R in 246 healthy individuals and 116 individuals attending periodic control for malignant melanoma development, 50 of which were diagnosed with FAMMM. It was observed that individuals with any two grouped MC1R...

  9. 气动矛系统性能仿真分析%The Simulation Analysis on Performance of Hammerhead Mole

    Institute of Scientific and Technical Information of China (English)

    于晓琳; 闫明印

    2011-01-01

    The structure and working principles of hammerhead mole system were analyzed, and the simulation computation was made by MATLAB based on the dynamic simulation model of working hammerhead mole system. The factors affecting the performance of hammerhead mole were analyzed, and the relationship between affecting factors and performance parameters was studied. The results can be a reference to the design of hammerhead mole.%分析气动矛系统的结构及工作原理,在建立气动矛系统工作状态下动力学仿真数学模型的基础上,利用MATLAB软件对Hammerhead12”型气动矛进行仿真,并对影响气动矛系统性能的各因素进行仿真分析,研究气动矛性能与各影响因素的关系.分析和研究结果可为气动矛的设计提供参考.

  10. Dynamic Thermodynamics with Internal Energy, Volume, and Amount of Moles as States : Application to Liquefied Gas Tank

    NARCIS (Netherlands)

    Arendsen, A. R. J.; Versteeg, G. F.

    2009-01-01

    Dynamic models for process design, optimization, and control usually solve a set of heat and/or mass balances as a function of time and/or position in the process. To obtain more robust dynamic models and to minimize the amount of assumptions, internal energy, volume, and amount of moles are chosen

  11. Effect of mole (Talpaеuropаеa digging activity on soil microflora in case of soil cadmium pollution

    Directory of Open Access Journals (Sweden)

    O. Y. Pakhomov

    2006-01-01

    Full Text Available Influence of fossorial activity of European mole Talpa еuropаеа on number and distribution of soil microorganisms under conditions of cadmium pollution of the soil is characterized. Mammals’ fossorial activity is an important natural ecological factor that contributes to microflora rehabilitation and development under conditions of contamination.

  12. HP3 on ExoMars - Cutting airbag cloths with the sharp tip of a mechanical mole

    Science.gov (United States)

    Krause, C.; Izzo, M.; Re, E.; Mehls, C.; Richter, L.; Coste, P.

    2009-04-01

    The HP3 - Heat Flow and Physical Properties Package - is planned to be one of the Humboldt lander-based instruments on the ESA ExoMars mission. HP3 will allow the measurement of the subsurface temperature gradient and physical as well as thermophysical properties of the subsurface regolith of Mars down to a depth of 5 meters. From these measurements, the planetary heat flux can be inferred. The HP³ instrument package consists of a mole trailing a package of thermal and electrical sensors into the regolith. Beside the payload elements Thermal Excitation and Measurement Suite and a Permittivity Probe the HP3 experiment includes sensors to detect the forward motion and the tilt of the HP3 payload compartment. The HP3 experiment will be integrated into the lander platform of the ExoMars mission. The original accommodation featured a deployment device or a robotic arm to place HP3 onto the soil outside the deflated lander airbags. To avoid adding such deployment devices, it was suggested that the HP3 mole should be capable of piercing the airbags under the lander. The ExoMars lander airbag is made of 4 Kevlar layers (2 abrasive and 2 bladders). A double fold of the airbag (a worst case) would represent a pile of 12 layers. An exploratory study has examined the possibility of piercing airbag cloths by adding sharp cutting blades on the tip of a penetrating mole. In the experimental setup representative layers were laid over a Mars soil simulant. Initial tests used a hammer-driven cutting tip and had moderate to poor results. More representative tests used a prototype of the HP3 mole and were fully successful: the default 4 layer configuration was pierced as well as the 12 layer configuration, the latter one within 3 hours and about 3000 mole strokes This improved behaviour is attributed to the use of representative test hardware where guidance and suppression of mole recoil were concerned. The presentation will provide an explanation of the technical requirements on

  13. The Subaru Coronagraphic Extreme AO Project

    Science.gov (United States)

    Martinache, Frantz; Guyon, O.; Lozi, J.; Tamura, M.; Hodapp, K.; Suzuki, R.; Hayano, Y.; McElwain, M. W.

    2009-01-01

    While the existence of large numbers of extrasolar planets around solar type stars has been unambiguously demonstrated by radial velocity, transit and microlensing surveys, attempts at direct imaging with AO-equipped large telescopes remain unsuccessful. Because they supposedly offer more favorable contrast ratios, young systems consitute prime targets for imaging. Such observations will provide key insights on the formation and early evolution of planets and disks. Current surveys are limited by modest AO performance which limits inner working angle to 0.2", and only reach maximum sensitivity outside 1". This translates into orbital distances greater than 10 AU even on most nearby systems, while only 5 % of the known exoplanets have a semimajor axis greater than 10 AU. This calls for a major change of approach in the techniques used for direct imaging of the direct vicinity of stars. A sensible way to do the job is to combine coronagraphy and Extreme AO. Only accurate and fast control of the wavefront will permit the detection of high contrast planetary companions within 10 AU. The SCExAO system, currently under assembly, is an upgrade of the HiCIAO coronagraphic differential imaging camera, mounted behind the 188-actuator curvature AO system on Subaru Telescope. This platform includes a 1000-actuator MEMS deformable mirror for high accuracy wavefront correction and a PIAA coronagraph which delivers high contrast at 0.05" from the star (5 AU at 100 pc). Key technologies have been validated in the laboratory: high performance wavefront sensing schemes, spider vanes and central obstruction removal, and lossless beam apodization. The project is designed to be highly flexible to continuously integrate new technologies with high scientific payoff. Planned upgrades include an integral field unit for spectral characterization of planets/disks and a non-redundant aperture mask to push the performance of the system toward separations less than lambda/D.

  14. Variation of CO2 mole fraction in the lower free troposphere, in the boundary layer and at the surface

    Directory of Open Access Journals (Sweden)

    J. Tarniewicz

    2012-05-01

    Full Text Available Eight years of occasional flask air sampling and 3 yr of frequent in situ measurements of carbon dioxide (CO2 vertical profiles on board of a small aircraft, over a tall tower greenhouse gases monitoring site in Hungary are used for the analysis of the variations of vertical profile of CO2 mole fraction. Using the airborne vertical profiles and the measurements along the 115 m tall tower it is shown that the measurements at the top of the tower estimate the mean boundary layer CO2 mole fraction during the mid-afternoon fairly well, with an underestimation of 0.27–0.85 μmol mol−1 in summer, and an overestimation of 0.66–1.83 μmol mol−1 in winter. The seasonal cycle of CO2 mole fraction is damped with elevation. While the amplitude of the seasonal cycle is 28.5 μmol mol−1 at 10 m above the ground, it is only 10.7 μmol mol−1 in the layer of 2500–3000 m corresponding to the lower free atmosphere above the well-mixed boundary layer. The maximum mole fraction in the layer of 2500–3000 m can be observed around 25 March on average, two weeks ahead of that of the marine boundary layer reference (GLOBALVIEW. By contrast, close to the ground, the maximum CO2 mole fraction is observed late December, early January. The specific seasonal behavior is attributed to the climatology of vertical mixing of the atmosphere in the Carpathian Basin.

  15. Adaptive methylation regulation of p53 pathway in sympatric speciation of blind mole rats, Spalax.

    Science.gov (United States)

    Zhao, Yang; Tang, Jia-Wei; Yang, Zhi; Cao, Yi-Bin; Ren, Ji-Long; Ben-Abu, Yuval; Li, Kexin; Chen, Xue-Qun; Du, Ji-Zeng; Nevo, Eviatar

    2016-02-23

    Epigenetic modifications play significant roles in adaptive evolution. The tumor suppressor p53, well known for controlling cell fate and maintaining genomic stability, is much less known as a master gene in environmental adaptation involving methylation modifications. The blind subterranean mole rat Spalax eherenbergi superspecies in Israel consists of four species that speciated peripatrically. Remarkably, the northern Galilee species Spalax galili (2n = 52) underwent adaptive ecological sympatric speciation, caused by the sharply divergent chalk and basalt ecologies. This was demonstrated by mitochondrial and nuclear genomic evidence. Here we show that the expression patterns of the p53 regulatory pathway diversified between the abutting sympatric populations of S. galili in sharply divergent chalk-basalt ecologies. We identified higher methylation on several sites of the p53 promoter in the population living in chalk soil (chalk population). Site mutagenesis showed that methylation on these sites linked to the transcriptional repression of p53 involving Cut-Like Homeobox 1 (Cux1), paired box 4 (Pax 4), Pax 6, and activator protein 1 (AP-1). Diverse expression levels of p53 between the incipiently sympatrically speciating chalk-basalt abutting populations of S. galili selectively affected cell-cycle arrest but not apoptosis. We hypothesize that methylation modification of p53 has adaptively shifted in supervising its target genes during sympatric speciation of S. galili to cope with the contrasting environmental stresses of the abutting divergent chalk-basalt ecologies.

  16. Cardiac function of the naked mole-rat: ecophysiological responses to working underground.

    Science.gov (United States)

    Grimes, Kelly M; Voorhees, Andrew; Chiao, Ying Ann; Han, Hai-Chao; Lindsey, Merry L; Buffenstein, Rochelle

    2014-03-01

    The naked mole-rat (NMR) is a strictly subterranean rodent with a low resting metabolic rate. Nevertheless, it can greatly increase its metabolic activity to meet the high energetic demands associated with digging through compacted soils in its xeric natural habitat where food is patchily distributed. We hypothesized that the NMR heart would naturally have low basal function and exhibit a large cardiac reserve, thereby mirroring the species' low basal metabolism and large metabolic scope. Echocardiography showed that young (2-4 yr old) healthy NMRs have low fractional shortening (28 ± 2%), ejection fraction (43 ± 2%), and cardiac output (6.5 ± 0.4 ml/min), indicating low basal cardiac function. Histology revealed large NMR cardiomyocyte cross-sectional area (216 ± 10 μm(2)) and cardiac collagen deposition of 2.2 ± 0.4%. Neither of these histomorphometric traits was considered pathological, since biaxial tensile testing showed no increase in passive ventricular stiffness. NMR cardiomyocyte fibers showed a low degree of rotation, contributing to the observed low NMR cardiac contractility. Interestingly, when the exercise mimetic dobutamine (3 μg/g ip) was administered, NMRs showed pronounced increases in fractional shortening, ejection fraction, cardiac output, and stroke volume, indicating an increased cardiac reserve. The relatively low basal cardiac function and enhanced cardiac reserve of NMRs are likely to be ecophysiological adaptations to life in an energetically taxing environment. PMID:24363308

  17. Functional characteristics of the naked mole rat μ-opioid receptor.

    Directory of Open Access Journals (Sweden)

    Melanie Busch-Dienstfertig

    Full Text Available While humans and most animals respond to µ-opioid receptor (MOR agonists with analgesia and decreased aggression, in the naked mole rat (NMR opioids induce hyperalgesia and severe aggression. Single nucleotide polymorphisms in the human mu-opioid receptor gene (OPRM1 can underlie altered behavioral responses to opioids. Therefore, we hypothesized that the primary structure of the NMR MOR may differ from other species. Sequencing of the NMR oprm1 revealed strong homology to other mammals, but exposed three unique amino acids that might affect receptor-ligand interactions. The NMR and rat oprm1 sequences were cloned into mammalian expression vectors and transfected into HEK293 cells. Radioligand binding and 3'-5'-cyclic adenosine monophosphate (cAMP enzyme immunoassays were used to compare opioid binding and opioid-mediated cAMP inhibition. At normalized opioid receptor protein levels we detected significantly lower [3H]DAMGO binding to NMR compared to rat MOR, but no significant difference in DAMGO-induced cAMP inhibition. Strong DAMGO-induced MOR internalization was detectable using radioligand binding and confocal imaging in HEK293 cells expressing rat or NMR receptor, while morphine showed weak or no effects. In summary, we found minor functional differences between rat and NMR MOR suggesting that other differences e.g. in anatomical distribution of MOR underlie the NMR's extreme reaction to opioids.

  18. Large-Scale DNS of Gas-Solid Flow on Mole-8.5

    CERN Document Server

    Xiong, Qingang; Li, Bo; Xua, Ji; Fang, Xiaojian; Wang, Junwu; He, Xianfeng; Wang, Xiaowei; Wang, Limin; Ge, Wei; Li, Jinghai

    2010-01-01

    Direct numerical simulation (DNS) for gas-solid flow is implemented on a multi-scale supercomputing system, Mole-8.5, featuring massive parallel GPU-CPU hybrid computing, for which the lattice Boltzmann method (LBM) is deployed together with the immersed moving boundary (IMB) method and discrete element method (DEM). A two-dimensional suspension with about 1,166,400 75-micron solid particles distributed in an area of 11.5cm x46cm, and a three-dimensional suspension with 129,024 solid particles in a domain of 0.384cm x1.512cm x0.384cm are fully-resolved below particle scale and distinct multi-scale heterogeneity are observed. Almost 20-fold speedup is achieved on one Nvidia C2050 GPU over one core of Intel E5520 CPU in double precision, and nearly ideal scalability is maintained when using up to 672 GPUs. The simulations demonstrate that LB-IMB-DEM modeling with parallel GPU computing may suggest a promising approach for exploring the fundamental mechanisms and constitutive laws of complex gas-solid flow, whic...

  19. Antagonistic Coevolution Drives Whack-a-Mole Sensitivity in Gene Regulatory Networks.

    Directory of Open Access Journals (Sweden)

    Jeewoen Shin

    2015-10-01

    Full Text Available Robustness, defined as tolerance to perturbations such as mutations and environmental fluctuations, is pervasive in biological systems. However, robustness often coexists with its counterpart, evolvability--the ability of perturbations to generate new phenotypes. Previous models of gene regulatory network evolution have shown that robustness evolves under stabilizing selection, but it is unclear how robustness and evolvability will emerge in common coevolutionary scenarios. We consider a two-species model of coevolution involving one host and one parasite population. By using two interacting species, key model parameters that determine the fitness landscapes become emergent properties of the model, avoiding the need to impose these parameters externally. In our study, parasites are modeled on species such as cuckoos where mimicry of the host phenotype confers high fitness to the parasite but lower fitness to the host. Here, frequent phenotype changes are favored as each population continually adapts to the other population. Sensitivity evolves at the network level such that point mutations can induce large phenotype changes. Crucially, the sensitive points of the network are broadly distributed throughout the network and continually relocate. Each time sensitive points in the network are mutated, new ones appear to take their place. We have therefore named this phenomenon "whack-a-mole" sensitivity, after a popular fun park game. We predict that this type of sensitivity will evolve under conditions of strong directional selection, an observation that helps interpret existing experimental evidence, for example, during the emergence of bacterial antibiotic resistance.

  20. Two novel mutations in the KHDC3L gene in Asian patients with recurrent hydatidiform mole

    Science.gov (United States)

    Rezaei, Maryam; Nguyen, Ngoc Minh Phuong; Foroughinia, Leila; Dash, Pratima; Ahmadpour, Fatemeh; Verma, Ishwar Chandra; Slim, Rima; Fardaei, Majid

    2016-01-01

    Recurrent hydatidiform mole (RHM) is defined by the occurrence of repeated molar pregnancies in affected women. Two genes, NLRP7 and KHDC3L, play a causal role in RHM and are responsible for 48–80% and 5% of cases, respectively. Here, we report the results of screening these two genes for mutations in one Iranian and one Indian patient with RHM. No mutations in NLRP7 were identified in the two patients. KHDC3L sequencing identified two novel protein-truncating mutations in a homozygous state, a 4-bp deletion, c.17_20delGGTT (p.Arg6Leufs*7), in the Iranian patient and a splice mutation, c.349+1G>A, that affects the invariant donor site at the junction of exon 2 and intron 2 in the Indian patient. To date, only four mutations in KHDC3L have been reported. The identification of two additional mutations provides further evidence for the important role of KHDC3L in the pathophysiology of RHM and increases the diversity of mutations described in Asian populations. PMID:27621838

  1. Hormones, reproduction and disease in the longest-lived rodent: the naked mole rat

    Directory of Open Access Journals (Sweden)

    Manlio Vinciguerra

    2011-05-01

    Full Text Available Aging is an inescapable human condition, made of hormonal, physical, and behavioral changes. Age-related illnesses and decline result from the interactions between genes and the environment. Life expectancy dramatically increased in the last century with the improvement in health cares and quality of life in the Western World. Despite these advances, the last 20 years of our life are often accompanied by an increased incidence of hormonalrelated diseases, such as cancer, metabolic, cardiovascular and neurological dysturbances. Aging research recently uncovered many of the molecular pathways involved in nutrients and hormonal regulation, and also involved in organism life span using simple laboratory animal model. However this knowledge did not translate in an ameliorated aging and cure for hormonal diseases in humans. A breakthrough in aging research came from recent studies on the longest-lived rodent [the naked mole rat (NMR]. NMR are able to reach ~30 years of age in good health. Because of their longevity and sustained health, NMR are a research model for successful aging. The most striking feature of NMR is perhaps their eusociality. Unique among mammals (eusociality is observed in insects such as bees and ants, NMR are organized in highly cooperative colonies. The aim of this review is to summarize our knowledge on hormonal and reproductive aspects in NMR. Furthermore, their resistance to pathological insults will be discussed.

  2. Cryptic sex? Estimates of genome exchange in unisexual mole salamanders (Ambystoma sp.).

    Science.gov (United States)

    Gibbs, H Lisle; Denton, Robert D

    2016-06-01

    Cryptic sex has been argued to explain the exceptional longevity of certain parthenogenetic vertebrate lineages, yet direct measurements of genetic exchange between sexual and apparently parthenogenetic forms are rare. Female unisexual mole salamanders (Ambystoma sp.) are the oldest known unisexual vertebrate lineage (~5 million years), and one hypothesis for their persistence is that allopolyploid female unisexuals periodically exchange haploid genomes 'genome exchange' during gynogenetic reproduction with males from sympatric sexual species. We test this hypothesis by using genome-specific microsatellite DNA markers to estimate the rates of genome exchange between sexual males and unisexual females in two ponds in NE Ohio. We also test the prediction that levels of gene flow should be higher for 'sympatric' (sexual males present) genomes in unisexuals compared to 'allopatric' (sexual males absent) unisexual genomes. We used a model testing framework in the coalescent-based program MIGRATE-N to compare models where unidirectional gene flow is present and absent between sexual species and unisexuals. As predicted, our results show higher levels of gene flow between sexuals and sympatric unisexual genomes compared to lower (likely artefactual) levels of gene flow between sexuals and allopatric unisexual genomes. Our results provide direct evidence that genome exchange between sexual and unisexual Ambystoma occurs and demonstrate that the magnitude depends on which sexual species are present. The relatively high levels of gene flow suggest that unisexuals must be at a selective advantage over sexual forms so as to avoid extinction due to genetic swamping through genome exchange. PMID:27100619

  3. Influence of the mole penetrator on measurements of heat flow in lunar subsurface layers

    Science.gov (United States)

    Wawrzaszek, Roman; Drogosz, Michal; Seweryn, Karol; Banaszkiewicz, Marek; Grygorczuk, Jerzy

    Measuring the thermal gradient in subsurface layers is a basic method of determination the heat flux from the interior of a planetary body to its surface. In case of the Moon, such measurements complemented with the results of theoretical analysis and modeling can significantly improve our understanding of the thermal and geological evolution of the Moon. In practice, temperature gradient measurements are performed by at least two sensors located at different depths under the surface. These sensors will be attached to a penetrator [1] or to a cable pulled behind the penetrator. In both cases the object that carries the sensors, e.g. penetrator, perturb temperature measurements. In our study we analyze a case of two thermal sensors attached to the ends of 350mm long penetrator made of a composite material. In agreement with the studies of other authors we have found that the penetrator should be placed at the depth of 2-3 meters, where periodic changes of the temperature due to variation of solar flux at the surface are significantly smaller than the error of temperature measurement. The most important result of our analysis is to show how to deconvolve the real gradient of the temperature from the measurements perturbed by the penetrator body. In this way it will be possible to more accurately determine heat flux in the lunar regolith. [1] Grygorczuk J., Seweryn K., Wawrzaszek R., Banaszkiewicz M., Insertion of a Mole Pene-trator -Experimental Results, /39th Lunar and Planetary Science Conference /League City, Texas 2008

  4. Protocol for the MoleMate™ UK Trial: a randomised controlled trial of the MoleMate system in the management of pigmented skin lesions in primary care [ISRCTN 79932379

    Directory of Open Access Journals (Sweden)

    Wilson Edward CF

    2010-05-01

    Full Text Available Abstract Background Suspicious pigmented lesions are a common presenting problem in general practice consultations; while the majority are benign a small minority are melanomas. Differentiating melanomas from other pigmented lesions in primary care is challenging: currently, 95% of all lesions referred to a UK specialist are benign. The MoleMate system is a new diagnostic aid, incorporating a hand-held SIAscopy scanner with a primary care diagnostic algorithm. This trial tests the hypothesis that adding the MoleMate system to current best primary care practice will increase the proportion of appropriate referrals of suspicious pigmented lesions to secondary care compared with current best practice alone. Methods/design The MoleMate UK Trial is a primary care based multi-centre randomised controlled trial, with randomisation at patient level using a validated block randomisation method for two age groups (45 years and under; 46 years and over. We aim to recruit adult patients seen in general practice with a pigmented skin lesion that cannot immediately be diagnosed as benign and the patient reassured. The trial has a 'two parallel groups' design, comparing 'best practice' with 'best practice' plus the MoleMate system in the intervention group. The primary outcome is the positive predictive value (PPV of referral defined as the proportion of referred lesions seen by secondary care experts that are considered 'clinically significant' (i.e. biopsied or monitored. Secondary outcomes include: the sensitivity, specificity and negative predictive value (NPV of the decision not to refer; clinical outcomes (melanoma thickness, 5 year melanoma incidence and mortality; clinician outcomes (Index of Suspicion, confidence, learning effects; patient outcomes (satisfaction, general and cancer-specific worry, and cost-utility. Discussion The MoleMate UK Trial tests a new technology designed to improve the management of suspicious pigmented lesions in primary care

  5. FATORES ASSOCIADOS AO BAIXO PESO AO NASCER NO ESTADO DE GOIÁS

    Directory of Open Access Journals (Sweden)

    Ruth Minamisava

    2004-12-01

    Full Text Available Recém-nascidos de baixo peso ao nascer (RNBP são considerados problemas de saúde pública pela associação com altas taxas de mortalidade e morbidade. Nenhum estudo prévio sobre fatores associados ao RNBP na região central do Brasil foi encontrado na literatura. Assim, este estudo teve como objetivo identificar as prevalências e os fatores associados ao baixo peso ao nascer entre nascidos vivos no Estado de Goiás, Brasil. Foi realizado um estudo transversal tendo como fonte de dados o Sistema de Informações de Nascidos Vivos ligado ao Ministério da Saúde. Examinou-se todos os 92.745 recém-nascidos de gestação única residentes no estado de Goiás, no ano 2000. Usou-se análise de regressão logística para identificar os fatores associados ao RNBP (< 2500 g. Em Goiás, os RNBP apresentaram uma prevalência de 5,96% e os fatores associados ao baixo peso ao nascer foram: prematuridade, baixa e avançada idade materna, mulheres não casadas, menos de sete consultas de pré-natal, parto não hospitalar e neonatos do sexo feminino. Ações intersetoriais são necessárias para reduzir as desigualdades da saúde materna e infantil.

  6. Sensibilidade da rosa 'Osiana' ao etileno

    Directory of Open Access Journals (Sweden)

    Delaine Cristina Cordeiro

    2011-01-01

    Full Text Available Os objetivos deste trabalho foram determinar a sensibilidade e as respostas da rosa cultivar Osiana (Rosa × hybrida à presença de etileno ao longo da vida pós-colheita. Para determinar a sensibilidade da flor ao etileno, hastes foram cortadas e colocadas em câmaras herméticas e em seguida tratadas por 24 horas com diferentes concentrações de etileno variando de 0,0; 0,1; 1,0; 10; 100 e 1000 µL L-1do ar no interior da câmara. A rosa teve a vida pós-colheita reduzida pelo etileno, quando exposta a concentração igual ou superior a 10 µL L-1 de etileno. As flores tratadas com no mínimo de 10 µL L-1de etileno desenvolveram necrose, murcha e abscisão prematura das pétalas ainda túrgidas. As concentrações de 0,1 e 1,0 µL L-1de etileno estimularam a abertura do botão floral durante o período de 24 horas de exposição ao etileno, sem no entanto, reduzir a vida pós-colheita. A rosa 'Osiana' pode ser classificada como uma cultivar sensível ao etileno e a concentração influência os processos estimulados.

  7. MEMS DM development at Iris AO, Inc.

    Science.gov (United States)

    Helmbrecht, Michael A.; He, Min; Kempf, Carl J.; Besse, Marc

    2011-03-01

    Iris AO is actively developing piston-tip-tilt (PTT) segmented MEMS deformable mirrors (DM) and adaptive optics (AO) controllers for these DMs. This paper discusses ongoing research at Iris AO that has advanced the state-of-the-art of these devices and systems over the past year. Improvements made to open-loop operation and mirror fabrication enables mirrors to open-loop flatten to 4 nm rms. Additional testing of an anti snap-in technology was conducted and demonstrates that the technology can withstand 100 million snap-in events without failure. Deformable mirrors with dielectric coatings are shown that are capable of handling 630 W/cm2 of incident laser power. Over a localized region on the segment, the dielectric coatings can withstand 100kW/cm2 incident laser power for 30 minutes. Results from the first-ever batch of PTT489 DMs that were shipped to pilot customers are reported. Optimizations made to the open-loop PTT controller are shown to have latencies of 157.5 μs and synchronous array update rates of nearly 6.5 kHz. Finally, plans for the design and fabrication of the next-generation PTT939 DM are presented.

  8. Into the Blue: AO Science in the Visible with MagAO

    Science.gov (United States)

    Close, Laird; Males, Jared; Morzinski, Katie; Kopon, Derek; Follette, Kate; Rodigas, Timothy; Hinz, Philip; Wu, Ya-Lin; Puglisi, Alfio; Esposito, Simone; Riccardi, Armando; Pinna, Enrico; Xompero, Marco; Briguglio, Runa; Uomoto, Alan; Hare, Tison

    2013-12-01

    The Magellan Clay telescope is a 6.5m Gregorian telescope located in Chile at Las Campanas Observatory. We have fabricated an 85 cm diameter aspheric adaptive secondary with our subcontractors and partners, MagAO passed acceptance tests in spring 2012, and the entire System was commissioned from Nov 17 to Dec 7, 2012. This secondary has 585 actuators with < 1 msec response times (0.7 ms typically). We fabricated a high order (585 mode) pyramid wavefront sensor (similar to that of LBT's FLAO). The relatively high actuator count allows moderate Strehls to be obtained in the visible (0.63-1.05 microns). We have built an CCD science camera called "jVisAO". On-sky long exposures (60s) achieve 30% Strehls at 0.62 microns (r') with the VisAO camera in 0.5" seeing with bright R < 8 mag stars. These relatively high optical wavelength Strehls are made possible by our powerful combination of a next generation ASM and a Pyramid WFS with 200-400 controlled modes and 1000 Hz loop frequencies. To minimize non-common path errors and enable visible AO the VisAO science camera is fed by an advanced triplet ADC and is piggy-backed on the WFS optical board itself. Despite the ability to make 25 mas images we still have ~4 mas of resolution loss to residual vibrations. We will discuss what the most difficult aspects are for visible AO on ELTs scaling from our experience with MagAO.

  9. The Insulin-Like Growth Factor System in the Long-Lived Naked Mole-Rat.

    Science.gov (United States)

    Brohus, Malene; Gorbunova, Vera; Faulkes, Chris G; Overgaard, Michael T; Conover, Cheryl A

    2015-01-01

    Naked mole-rats (Heterocephalus glaber) (NMRs) are the longest living rodents known. They show negligible senescence, and are resistant to cancers and certain damaging effects associated with aging. The insulin-like growth factors (IGFs) have pluripotent actions, influencing growth processes in virtually every system of the body. They are established contributors to the aging process, confirmed by the demonstration that decreased IGF signaling results in life-extending effects in a variety of species. The IGFs are likewise involved in progression of cancers by mediating survival signals in malignant cells. This report presents a full characterization of the IGF system in the NMR: ligands, receptors, IGF binding proteins (IGFBPs), and IGFBP proteases. A particular emphasis was placed on the IGFBP protease, pregnancy-associated plasma protein-A (PAPP-A), shown to be an important lifespan modulator in mice. Comparisons of IGF-related genes in the NMR with human and murine sequences indicated no major differences in essential parts of the IGF system, including PAPP-A. The protease was shown to possess an intact active site despite the report of a contradictory genome sequence. Furthermore, PAPP-A was expressed and translated in NMRs cells and retained IGF-dependent proteolytic activity towards IGFBP-4 and IGF-independent activity towards IGFBP-5. However, experimental data suggest differential regulatory mechanisms for PAPP-A expression in NMRs than those described in humans and mice. This overall description of the IGF system in the NMR represents an initial step towards elucidating the complex molecular mechanisms underlying longevity, and how these animals have evolved to ensure a delayed and healthy aging process. PMID:26694858

  10. The Insulin-Like Growth Factor System in the Long-Lived Naked Mole-Rat.

    Directory of Open Access Journals (Sweden)

    Malene Brohus

    Full Text Available Naked mole-rats (Heterocephalus glaber (NMRs are the longest living rodents known. They show negligible senescence, and are resistant to cancers and certain damaging effects associated with aging. The insulin-like growth factors (IGFs have pluripotent actions, influencing growth processes in virtually every system of the body. They are established contributors to the aging process, confirmed by the demonstration that decreased IGF signaling results in life-extending effects in a variety of species. The IGFs are likewise involved in progression of cancers by mediating survival signals in malignant cells. This report presents a full characterization of the IGF system in the NMR: ligands, receptors, IGF binding proteins (IGFBPs, and IGFBP proteases. A particular emphasis was placed on the IGFBP protease, pregnancy-associated plasma protein-A (PAPP-A, shown to be an important lifespan modulator in mice. Comparisons of IGF-related genes in the NMR with human and murine sequences indicated no major differences in essential parts of the IGF system, including PAPP-A. The protease was shown to possess an intact active site despite the report of a contradictory genome sequence. Furthermore, PAPP-A was expressed and translated in NMRs cells and retained IGF-dependent proteolytic activity towards IGFBP-4 and IGF-independent activity towards IGFBP-5. However, experimental data suggest differential regulatory mechanisms for PAPP-A expression in NMRs than those described in humans and mice. This overall description of the IGF system in the NMR represents an initial step towards elucidating the complex molecular mechanisms underlying longevity, and how these animals have evolved to ensure a delayed and healthy aging process.

  11. Simulation of the shallow groundwater-flow system near Mole Lake, Forest County, Wisconsin

    Science.gov (United States)

    Fienen, Michael N.; Juckem, Paul F.; Hunt, Randall J.

    2011-01-01

    The shallow groundwater system near Mole Lake, Forest County, Wis. was simulated using a previously calibrated regional model. The previous model was updated using newly collected water-level measurements and refinements to surface-water features. The updated model was then used to calculate the area contributing recharge for one existing and two proposed pumping locations on lands of the Sokaogon Chippewa Community. Delineated 1-, 5-, and 10-year areas contributing recharge for existing and proposed wells extend from the areas of pumping to the northeast of the pumping locations. Steady-state pumping was simulated for two scenarios: a base pumping scenario using pumping rates that reflect what the Tribe expects to pump and a high pumping scenario, in which the rate was set to the maximum expected from wells installed in this area. In the base pumping scenario, pumping rates of 32 gallons per minute (gal/min; 46,000 gallons per day (gal/d)) from the existing well and 30 gal/min (43,000 gal/d) at each of the two proposed wells were simulated. The high pumping scenario simulated a rate of 70 gal/min (101,000 gal/d) from each of the three pumping wells to estimate of the largest areas contributing recharge that might be expected given what is currently known about the shallow groundwater system. The areas contributing recharge for both the base and high pumping scenarios did not intersect any modeled surface-water bodies; however, the high pumping scenario had a larger areal extent than the base pumping scenario and intersected a septic separator.

  12. Complete Hydatidiform Mole Presenting as a Placenta Accreta in a Twin Pregnancy with a Coexisting Normal Fetus: Case Report

    Directory of Open Access Journals (Sweden)

    Marijo Aguilera

    2012-01-01

    Full Text Available A twin pregnancy with a complete hydatidiform mole and a coexisting normal fetus (CHMF is a rare clinical scenario, and it carries many associated pregnancy and postnatal risks. Limited numbers of case studies exist reporting an outcome of live birth, and only three prior cases report the presentation of a hydatidiform mole as a placenta previa. We report a case of CHMF with the molar component presenting antenatally as a placenta previa, which ultimately resulted in placenta accreta at the time of delivery. A live male infant was delivered at 34 weeks’ gestation via planned cesarean section, and a hysterectomy was performed following unsuccessful removal of the molar component. We additionally utilized previously described methods of placing internal iliac balloons and ureteral stents prior to delivery. In such a high-risk pregnancy with a known molar previa component, these surgical preparation measures may be of benefit.

  13. Comparison of the regional CO2 mole fraction filtering approaches at a WMO/GAW regional station in China

    Science.gov (United States)

    Fang, S. X.; Tans, P. P.; Steinbacher, M.; Zhou, L. X.; Luan, T.

    2015-12-01

    The identification of atmospheric CO2 observation data which are minimally influenced by very local emissions/removals is essential for trend analysis, for the estimation of regional sources and sinks, and for the modeling of long-range transport of CO2. In this study, four approaches are used to filter the atmospheric CO2 observation records from 2009 to 2011 at one World Meteorological Organization/Global Atmosphere Watch (WMO/GAW) regional station (Lin'an, LAN) in China. The methods are based on the concentration of atmospheric black carbon (BC), on a statistical approach (robust extraction of baseline signal, REBS), on CH4 as an auxiliary tracer (AUX), and on meteorological parameters (MET). All approaches do suitably well to capture the seasonal CO2 cycle at LAN. Differences are observed in the average regional mole fractions with annual values in the REBS method at least 1.7 ± 0.2 ppm higher than the other methods. The BC method may underestimate the regional CO2 mole fractions during the winter-spring period and should be treated with caution. The REBS method is a purely statistical method and it may also introduce errors on the regional CO2 mole fraction evaluations, as the filtered trend may be influenced by the "noisy" raw data series. Although there are correlations between CH4 and CO2 mole fractions at LAN, the different source/sink regimes may introduce bias on the regional CO2 estimation in the AUX method, typically in summer. Overall, the MET method seems to be the most favorable because it mainly focuses on the influence of potential local sources and sinks, and considers diurnal variations and meteorological conditions. Using the MET method, the annual growth rate of regional CO2 at LAN is determined to be 3.1 ± 0.01 ppm yr-1 (standard error) from 2009 to 2011.

  14. Study of the regional CO2 mole fractions filtering approach at a WMO/GAW regional station in China

    Directory of Open Access Journals (Sweden)

    S. X. Fang

    2015-07-01

    Full Text Available The identification of atmospheric CO2 observation data which is minimally influenced by very local emissions/removals is essential for the estimation of trend analysis, regional sources and sinks, and for modeling of long-range transport of CO2. In this study, four approaches are used to filter the atmospheric CO2 observation records from 2009 to 2011 at one World Meteorological Organization/Global Atmosphere Watch (WMO/GAW regional station (Lin'an, LAN in China. The methods are based on the atmospheric black carbon concentration (BC, on a statistical approach (REBS, on CH4 as auxiliary tracer (AUX and on meteorological parameters (MET. All approaches do suitably well to capture the seasonal CO2 cycle at LAN. Differences are observed in the average regional mole fractions with annual values in the REBS method at least 1.7 ± 0.2 ppm higher than the other methods. The BC method may underestimate the regional CO2 mole fractions during winter-spring period and should be treated with caution. The REBS method is a purely statistical method and it may also introduce errors on the regional CO2 mole fractions evaluations, as the filtered trend may be deviated by the "noisy" raw data series. Although there are correlations between CH4 and CO2 mole fractions at LAN, the different source/sink regimes may introduce bias on the regional CO2 estimation in the AUX method, typically in summer. Overall, the MET method seems to be the most favorable because it mainly focuses on the influence of potential local sources and sinks and considers diurnal variations, local topography, and meteorological conditions. Using the MET method, the annual growth rate of regional CO2 at LAN is determined to be 3.1 ± 0.01 ppm yr−1 (standard error from 2009 to 2013.

  15. Pigmentary Markers in Danes – Associations with Quantitative Skin Colour, Nevi Count, Familial Atypical Multiple-Mole, and Melanoma Syndrome

    OpenAIRE

    Johansen, Peter; Andersen, Jeppe Dyrberg; Madsen, Linnea Nørgård; Ullum, Henrik; Glud, Martin; Børsting, Claus; Gniadecki, Robert; Morling, Niels

    2016-01-01

    To investigate whether pigmentation genes involved in the melanogenic pathway (melanogenesis) contributed to melanoma predisposition, we compared pigmentary genetics with quantitative skin pigmentation measurements, the number of atypical nevi, the total nevus count, and the familial atypical multiple mole and melanoma (FAMMM) syndrome. We typed 32 pigmentary SNP markers and sequenced MC1R in 246 healthy individuals and 116 individuals attending periodic control for malignant melanoma develop...

  16. Isolation and partial characterization of a highly divergent lineage of hantavirus from the European mole (Talpa europaea).

    Science.gov (United States)

    Gu, Se Hun; Kumar, Mukesh; Sikorska, Beata; Hejduk, Janusz; Markowski, Janusz; Markowski, Marcin; Liberski, Paweł P; Yanagihara, Richard

    2016-01-01

    Genetically distinct hantaviruses have been identified in five species of fossorial moles (order Eulipotyphla, family Talpidae) from Eurasia and North America. Here, we report the isolation and partial characterization of a highly divergent hantavirus, named Nova virus (NVAV), from lung tissue of a European mole (Talpa europaea), captured in central Poland in August 2013. Typical hantavirus-like particles, measuring 80-120 nm in diameter, were found in NVAV-infected Vero E6 cells by transmission electron microscopy. Whole-genome sequences of the isolate, designated NVAV strain Te34, were identical to that amplified from the original lung tissue, and phylogenetic analysis of the full-length L, M and S segments, using maximum-likelihood and Bayesian methods, showed that NVAV was most closely related to hantaviruses harbored by insectivorous bats, consistent with an ancient evolutionary origin. Infant Swiss Webster mice, inoculated with NVAV by the intraperitoneal route, developed weight loss and hyperactivity, beginning at 16 days, followed by hind-limb paralysis and death. High NVAV RNA copies were detected in lung, liver, kidney, spleen and brain by quantitative real-time RT-PCR. Neuropathological examination showed astrocytic and microglial activation and neuronal loss. The first mole-borne hantavirus isolate will facilitate long-overdue studies on its infectivity and pathogenic potential in humans. PMID:26892544

  17. The effects of oxotremorine, epibatidine, atropine, mecamylamine and naloxone in the tail-flick, hot-plate, and formalin tests in the naked mole-rat (Heterocephalus glaber)

    DEFF Research Database (Denmark)

    Dulu, Thomas D; Kanui, Titus I; Towett, Philemon K;

    2014-01-01

    The naked mole-rat (Heterocephalus glaber) is a promising animal model for the study of pain mechanisms, therefore a thorough characterization of this species is essential. The aim of the present study was to establish the naked mole-rat as a model for studying the cholinergic receptor system....... The present study demonstrated that stimulation of muscarinic and nicotinic receptors produces antinociceptive effects in the naked-mole rat. The reversal effect of atropine and mecamylamine suggests that this effect is mediated by cholinergic receptors. As naloxone increases the antinociceptive effects...

  18. 气动矛性能的计算机仿真研究%COMPUTER IMITATION STUDY ON THE PERFRMANCE OF IMPACT MOLE

    Institute of Scientific and Technical Information of China (English)

    张志兵; 刘静; 祝世平

    2001-01-01

    Abstract:This article analyses the factors affecting theperformance of impact mole in computer imitation method taking YH75 impact mole as an example and discusses the principle of selecting the design parametErs of impact mole.%[摘 要]运用计算机仿真方法,以YH75型气动矛为例,对影响气动矛性能的因素进行了分析,探讨了气动矛设计参数的选取原则。

  19. Esta é minha carta ao mundo

    Directory of Open Access Journals (Sweden)

    Fernanda Mourão

    2009-01-01

    Full Text Available A partir da primeira carta de Emily Dickinson (1830-1886 a Thomas Higginson, que então seria seu “preceptor” e interlocutor para sempre, este texto propõe uma leitura da obra da escritora norte-americana a partir do biografema da carta e da ideia de sua obra como “carta ao mundo” – conforme um de seus mais famosos poemas –, com todas as implicações trazidas pelo termo, e à luz das teorias de Roland Barthes, Maurice Blanchot e Silvina Rodrigues Lopes, entre outros.

  20. AoA Region: South Asian Seas

    Digital Repository Service at National Institute of Oceanography (India)

    Naqvi, S.W.A.

    the North Indian Ocean account for roughly one quarter of the world’s population, which makes the region’s coastal environment and resources especially vulnerable to human infl uences. AoA Region: South Asian Seas Wajih Naqvi © Wajih Naqvi Mandovi Estuary... important coastal fi sheries and provides direct sustenance to coastal communities from timber and other products. It is endowed also with rich biodiversity and wildlife. The most extensive mangrove forest in the region and the world’s second largest...

  1. FOREWORD: International Workshop on the Avogadro Constant and the Representation of the Silicon Mole

    Science.gov (United States)

    Basile, Giuseppe; Garfagnini, Raffaello; Mana, Giovanni; Peuto, Anna; Zosi, Gianfranco

    1994-01-01

    This special issue of Metrologia brings together contributions to the International Workshop on the Avogadro Constant and the Representation of the Silicon Mole, held in Turin, Italy, from 9 to 10 March 1994. It was organized by the Istituto di Metrologia "G Colonnetti" (IMGC) del Consiglio Nazionale delle Ricerche (CNR) and the Istituto di Fisica Generale "A Avogadro" (IFG) dell'Università di Tonno. It was sponsored by the CNR, the University of Turin, the Regione Piemonte, and the Commission of the European Communities DG XII. The workshop was a follow-up to previous international meetings held in Turin to commemorate Amedeo Avogadro, one in 1911 (the centenary of the publication of his hypothesis) and another in 1957 (the centenary of his death). On this occasion the workshop was motivated by the requirements of researchers engaged in the international project on the determination of the Avogadro constant by the x-ray crystal density method. Sixty-four participants representing eight countries attended the workshop. Doctoral students in metrology from Turin University and researchers working in adjacent fields were also present. The lectures were chosen so as to review the different aspects of this project, to illustrate progress in research, and to indicate future developments to scientists working in different fields of physics, metrology and technology. Complementary approaches to the NA determination based on electrical measurements were also reported and analysed. During the workshop, a number of specialist meetings allowed experts to discuss specific topics, to exchange information on results and techniques, and to improve the coordination of their activities. In their opening addresses, Prof. C Castagnoli (Director of the IFG) and Prof. L Crovini (Director of the IMGC) welcomed the participants and introduced the work in progress with a view to making a more precise determination of the Avogadro constant. They mentioned the expected influence of this

  2. AO Observations of Three Powerful Radio Galaxies

    Energy Technology Data Exchange (ETDEWEB)

    de Vries, W; van Bruegel, W; Quirrenbach, A

    2002-08-01

    The host galaxies of powerful radio sources are ideal laboratories to study active galactic nuclei (AGN). The galaxies themselves are among the most massive systems in the universe, and are believed to harbor supermassive black holes (SMBH). If large galaxies are formed in a hierarchical way by multiple merger events, radio galaxies at low redshift represent the end-products of this process. However, it is not clear why some of these massive ellipticals have associated radio emission, while others do not. Both are thought to contain SMBHs, with masses proportional to the total luminous mass in the bulge. It either implies every SMBH has recurrent radio-loud phases, and the radio-quiet galaxies happen to be in the ''low'' state, or that the radio galaxy nuclei are physically different from radio-quiet ones, i.e. by having a more massive SMBH for a given bulge mass. Here we present the first results from our adaptive optics imaging and spectroscopy pilot program on three nearby powerful radio galaxies. Initiating a larger, more systematic AO survey of radio galaxies (preferentially with Laser Guide Star equipped AO systems) has the potential of furthering our understanding of the physical properties of radio sources, their triggering, and their subsequent evolution.

  3. Effect of the Ti/B4C mole ratio on the reaction products and reaction mechanism in an Al–Ti–B4C powder mixture

    International Nuclear Information System (INIS)

    The effect of the Ti/B4C mole ratio on the fabrication behavior of Al composites is investigated using Al–Ti–B4C powder mixtures as reactants. The quick spontaneous infiltration (QSI) process combined with the combustion reaction and DTA analysis were used. According to the thermodynamic predictions, which are verified in the experimental results, TiB2 is formed in all the samples whereas TiC is only formed in reactants with a Ti/B4C mole ratio of more than two. The C atoms from the reacted B4C do not move into TiC but instead they move into Al3BC or Al4C3 when the Ti/B4C mole ratio is less than two. In addition, the reaction mechanism with a Ti/B4C mole ratio of 0.75 is investigated extensively. - Highlights: • The critical role of the Ti/B4C mole ratio on the reaction products of Al–Ti–B4C was studied using experiments. • The experimental results are also supported by thermodynamic calculations presented in this paper. • The reaction mechanism with a Ti/B4C mole ratio of 0.75 is investigated extensively

  4. Teasing apart socially-induced infertility in non-reproductive female Damaraland mole-rats, Fukomys damarensis (Rodentia: Bathyergidae).

    Science.gov (United States)

    Bennett, Nigel C

    2011-12-01

    The Damaraland mole-rat is a subterranean mammal exhibiting extreme reproductive skew with a single reproductive female in each colony responsible for procreation. Non-reproductive female colony members are physiologically suppressed while in the colony, exhibiting reduced concentrations of plasma luteinizing hormone (LH) and a decreased response of the pituitary, as measured by the release of bioactive LH, to an exogenous dose of gonadotrophin releasing hormone (GnRH). Removal of the reproductive female from the colony results in an elevation of LH and an enhanced response of the pituitary to a GnRH challenge in non-reproductive females comparable to reproductive females, implying control of reproduction in these individuals by the reproductive female. The Damaraland mole-rat is an ideal model for investigating the physiological and behavioral mechanisms that regulate the hypothalamo-pituitary-gonadal axis. In contrast, we know less about the control of reproduction at the level of the hypothalamus. The immunohistochemistry of the GnRH system of both reproductive and non-reproductive female Damaraland mole-rats has revealed no significant differences with respect to morphology, distribution or numbers of immunoreactive GnRH perikarya. We examined whether the endogenous opioid peptide beta-endorphin was responsible for the inhibition of the release of the GnRH from the neurons indirectly by measuring LH concentrations in these non-reproductive females following single, hourly and 8 hourly injections of the opioid antagonist naloxone. The results imply that the endogenous opioid peptide, beta-endorphin, is not responsible for the inhibition of GnRH release from the perikarya in non-reproductive females. Preliminary data examining the circulating levels of cortisol also do not support a role for circulating glucocorticoids. The possible role of kisspeptin is discussed.

  5. LGS-AO Imaging of Every Kepler Planet Candidate: the Robo-AO KOI Survey

    Science.gov (United States)

    Baranec, Christoph; Law, Nicholas; Morton, Timothy; Ziegler, Carl; Nofi, Larissa; Atkinson, Dani; Riddle, Reed

    2015-12-01

    The Robo-AO Kepler Planetary Candidate Survey is observing every Kepler planet candidate host star with laser adaptive optics imaging, to search for blended nearby stars which may be physically associated companions and/or responsible for transit false positives. We will present the results from searching for companions around over 3,000 Kepler planet hosts in 2012-2015. We will describe our first data release covering 715 planet candidate hosts, and give a preview of ongoing results including improved statistics on the likelihood of false positive planet detections in the Kepler dataset, many new planets in multiple star systems, and new exotic multiple star systems containing Kepler planets. We will also describe the automated Robo-AO survey data reduction methods, including a method of using the large ensemble of target observations as mutual point-spread-function references, along with a new automated companion-detection algorithm designed for extremely large adaptive optics surveys. Our first data release covered 715 objects, searching for companions from 0.15” to 2.5” separation with contrast up to 6 magnitudes. We measured the overall nearby-star-probability for Kepler planet candidates to be 7.4+/-1.0%, and we will detail the variations in this number with stellar host parameters. We will also discuss plans to extend the survey to other transiting planet missions such as K2 and TESS as Robo-AO is in the process of being re-deployed to the 2.1-m telescope at Kitt Peak for 3 years and a higher-contrast Robo-AO system is being developed for the 2.2-m UH telescope on Maunakea.

  6. Rentabilidade da tangerineira 'Ponkan' submetida ao raleio químico comparada com ao manejo convencional

    Directory of Open Access Journals (Sweden)

    Maria do Céu Monteiro Cruz

    2011-10-01

    Full Text Available A pesquisa foi conduzida em um pomar comercial, localizado no município de Perdões, região sul de Minas Gerais, com o objetivo de analisar e comparar a rentabilidade da produção da tangerineira 'Ponkan' (Citrus reticulata Blanco submetida ao raleio químico com o manejo convencional. Para se montar a matriz de coeficientes técnicos dos custos de produção e os indicadores de rentabilidade da cultura, os dados foram obtidos com os produtores da região e baseados em trabalho de pesquisa realizado no pomar, no período de dezembro de 2006 a julho de 2008. Foram utilizadas plantas com dez anos de enxertadas sobre limoeiro 'Cravo' (Citrus limonia Osbeck. No primeiro ano, o raleio químico foi realizado com aplicação de Ethephon na concentração de 600 mg L-1,e por ocasião da colheita foi avaliado o rendimento da produção nas plantas submetidas ao raleio químico e ao manejo convencional. No segundo ano, foi determinada a alternância de produção e a produtividade. A prática do raleio químico proporcionou maior rentabilidade, em termos de produtividade da tangerina 'Ponkan', que o manejo convencional, sem a adoção do raleio.

  7. Adesão ao tratamento da Hanseníase: dificuldades inerentes aos portadores

    Directory of Open Access Journals (Sweden)

    Izaildo Tavares Luna

    2010-12-01

    Full Text Available Esta pesquisa, realizada em Guaiúba, CE, Brasil, objetivou identificar as dificuldades de adesão ao tratamento pelos portadores de hanseníase, relacionando os fatores associados. Estudo qualitativo, cujos dados foram coletados a partir de uma visita domiciliária com roteiro de entrevista contendo sete questões norteadoras. Participaram pacientes com diagnóstico de hanseníase e histórico de não adesão ao tratamento. Utilizou-se o Modelo de Atividade de Vida de Roper, Logan e Tierney. As falas dos sujeitos foram categorizadas de acordo com as doze atividades de vida. A utilização do modelo possibilitou uma abordagem holística sobre as barreiras vivenciadas pelo hanseniano na adesão ao tratamento medicamentoso, de modo a conhecer as atividades de vida destes pacientes para possível adequação de ações voltadas a essa clientela.

  8. A survey of gastrointestinal parasites of olive baboons (Papio anubis) in human settlement areas of Mole National Park, Ghana.

    Science.gov (United States)

    Ryan, Sadie J; Brashares, Justin S; Walsh, Chesley; Milbers, Katherine; Kilroy, Cailean; Chapman, Colin A

    2012-08-01

    Fecal samples from 55 free-ranging olive baboons (Papio anubis) in Mole National Park, Ghana, were collected 22 June-7 July 2008 and analyzed for gastrointestinal parasites. This is the first survey of baboon gastrointestinal parasites in Ghana and provides baseline data for this area. Ninety-three percent of samples were infected, leaving 7% with no parasites observed. Of those infected, there was a 76% prevalence of strongyles, 53% Strongyloides spp., 11% Abbreviata caucasica , 62% prevalence of Balantidium coli (trophozoites and cysts identified), 4% Entomeba hystolytica/dispar, and 47% unidentified protozoan parasites. Of the strongyle infections, 9% were identified as Oesophagostamum sp. One sample contained an unidentified spirurid nematode that resembled Gongylonema sp. Mole has a mixed forest-savanna habitat, and baboons frequently range into human areas, which makes them subject to parasites from each habitat and multiple sources of exposure. We found a high prevalence of nematode parasites, consistent with a wet or cooler forest environment, or high rates of fecal contamination. The presence of Strongyloides sp., E. hystolitica/dispar, and B. coli suggest potential public health risk from baboons, but molecular identification of these parasites, and documentation of their presence in local human populations, would be necessary to confirm zoonotic transmission. PMID:22300265

  9. Transcriptome sequencing of the blind subterranean mole rat, Spalax galili: Utility and potential for the discovery of novel evolutionary patterns

    KAUST Repository

    Malik, Assaf

    2011-08-12

    The blind subterranean mole rat (Spalax ehrenbergi superspecies) is a model animal for survival under extreme environments due to its ability to live in underground habitats under severe hypoxic stress and darkness. Here we report the transcriptome sequencing of Spalax galili, a chromosomal type of S. ehrenbergi. cDNA pools from muscle and brain tissues isolated from animals exposed to hypoxic and normoxic conditions were sequenced using Sanger, GS FLX, and GS FLX Titanium technologies. Assembly of the sequences yielded over 51,000 isotigs with homology to ~12,000 mouse, rat or human genes. Based on these results, it was possible to detect large numbers of splice variants, SNPs, and novel transcribed regions. In addition, multiple differential expression patterns were detected between tissues and treatments. The results presented here will serve as a valuable resource for future studies aimed at identifying genes and gene regions evolved during the adaptive radiation associated with underground life of the blind mole rat. 2011 Malik et al.

  10. Long-term analysis of carbon dioxide and methane column-averaged mole fractions retrieved from SCIAMACHY

    Science.gov (United States)

    Schneising, Oliver; Buchwitz, Michael; Reuter, Maximilian; Heymann, Jens; Bovensmann, Heinrich; Burrows, John P.

    2010-05-01

    Carbon dioxide (CO2) and methane (CH4) are the two most important anthropogenic greenhouse gases contributing to climate change. Despite their importance our knowledge about their variable natural and anthropogenic sources and sinks has significant gaps. Satellite observations can add important global scale information on greenhouse gas sources and sinks provided the data are accurate and precise enough and are sensitive to the lowest atmospheric layers where the variability is largest. High sensitivity to near-surface greenhouse gas concentration changes can be achieved using reflected solar radiation in the near-infrared/shortwave-infrared (NIR/SWIR) spectral region. SCIAMACHY onboard ENVISAT (launch 2002) was the first and is now besides TANSO onboard GOSAT (launch 2009) the only satellite instrument currently in space covering important absorption bands of both gases in this spectral range. Global SCIAMACHY nadir observations from the time period 2003-2009 have been used to retrieve carbon dioxide and methane column-averaged mole fractions (which are the quantities needed for inverse modelling to get information on the sources and sinks) constituting seven years of greenhouse gas information derived from European EO data and offering temporal overlap with GOSAT. These new improved WFM-DOAS multi-year global data sets extending afore existing retrievals will be presented and discussed including an analysis of the long-term characteristics and comparison of the retrieved mole fractions with independent data, e.g., a first analysis of how the SCIAMACHY results compare with GOSAT retrievals for the overlapping time period.

  11. Adesao ao guia alimentar para populacao brasileira

    Directory of Open Access Journals (Sweden)

    Eliseu Verly Junior

    2013-12-01

    Full Text Available OBJETIVO : Analisar a adesão ao Guia Alimentar para População Brasileira. MÉTODOS : Amostra composta por participantes do Inquérito de Saúde de São Paulo (n = 1.661 que preencheram dois recordatórios de 24 horas. Foi utilizado modelo bivariado de efeito misto para a razão entre o consumo de energia do grupo de alimentos e o consumo calórico total. A razão estimada foi utilizada para calcular o percentual de indivíduos com consumo abaixo ou acima da recomendação. RESULTADOS : Pelo menos 80,0% da população consome abaixo do recomendado para: leite e derivados; frutas e sucos de frutas; e cereais, tubérculos e raízes; aproximadamente 60,0% para legumes e verduras; 30,0% para feijões; e 8,0% para carnes e ovos. Adolescentes apresentaram a maior inadequação para legumes e verduras (90,0%, e o estrato de maior renda foi associado à menor inadequação para óleos, gorduras e sementes oleaginosas (57,0%. CONCLUSÕES : Foi observado consumo inadequado dos grupos de alimentos relacionados com aumento do risco de doenças crônicas.

  12. Brachyuran Crabs collected at Curaçao

    NARCIS (Netherlands)

    Rathbun, Mary J.

    1924-01-01

    In 1920 a report ¹) on Dr. BOEKE’S collection of crabs and shrimps from Curaçao and other Dutch West Indian Islands was published. Dr. VAN DER HORST’S collection forms an important addition to the fauna of Curaçao, especially as to the Xanthids and Majids, or spider crabs. Four new species were disc

  13. Sensibilidade de estirpes de Bradyrhizobium ao glyphosate

    Directory of Open Access Journals (Sweden)

    Rodrigo Josemar Seminoti Jacques

    2010-02-01

    Full Text Available A aplicação do glyphosate sobre a soja resistente a este herbicida pode causar prejuízos à simbiose com o rizóbio. O objetivo deste trabalho foi avaliar a sensibilidade ao herbicida glyphosate de três estirpes de Bradyrhizobium recomendadas para a produção de inoculantes de sementes de soja no Brasil. Avaliou-se o efeito das concentrações de 0,0; 5,4; 10,8; 21,6 e 43,2 µg L-1 do ingrediente ativo do glyphosate [N-(fosfonometil glicina] no meio YM líquido sobre o crescimento de B. japonicum (estirpe SEMIA 5079 e de B. elkanii (estirpe SEMIA 5019 e estirpe SEMIA 587, por meio de leituras das densidades óticas e geração de curvas de crescimento. As reduções de crescimento na presença da menor concentração do glyphosate foram de 18% para SEMIA 5079, 29% para SEMIA 5019 e de 35% para SEMIA 587, sendo, de modo geral, quanto maior a concentração do herbicida no meio de cultura maior a inibição do crescimen­to. As estirpes apresentaram sensibilidade diferencial somente às concentrações mais baixas do glyphosate; nesse caso, foi possível determinar a seguinte ordem de sensibilidade: SEMIA 587 > SEMIA 5019 > SEMIA 5079. Essa sensibilidade diferencial é dependente da concentração do herbicida, pois na presença de 43,2 µg L-1 todas as estirpes tiveram seu crescimento severamente reduzido, não havendo diferença entre elas.

  14. First closed-loop visible AO test results for the advanced adaptive secondary AO system for the Magellan Telescope: MagAO's performance and status

    Science.gov (United States)

    Close, Laird M.; Males, Jared R.; Kopon, Derek A.; Gasho, Victor; Follette, Katherine B.; Hinz, Phil; Morzinski, Katie; Uomoto, Alan; Hare, Tyson; Riccardi, Armando; Esposito, Simone; Puglisi, Alfio; Pinna, Enrico; Busoni, Lorenzo; Arcidiacono, Carmelo; Xompero, Marco; Briguglio, Runa; Quiros-Pacheco, Fernando; Argomedo, Javier

    2012-07-01

    The heart of the 6.5 Magellan AO system (MagAO) is a 585 actuator adaptive secondary mirror (ASM) with response times (0.7 ms typically). This adaptive secondary will allow low emissivity and high-contrast AO science. We fabricated a high order (561 mode) pyramid wavefront sensor (similar to that now successfully used at the Large Binocular Telescope). The relatively high actuator count (and small projected ~23 cm pitch) allows moderate Strehls to be obtained by MagAO in the “visible” (0.63-1.05 μm). To take advantage of this we have fabricated an AO CCD science camera called "VisAO". Complete “end-to-end” closed-loop lab tests of MagAO achieve a solid, broad-band, 37% Strehl (122 nm rms) at 0.76 μm (i’) with the VisAO camera in 0.8” simulated seeing (13 cm ro at V) with fast 33 mph winds and a 40 m Lo locked on R=8 mag artificial star. These relatively high visible wavelength Strehls are enabled by our powerful combination of a next generation ASM and a Pyramid WFS with 400 controlled modes and 1000 Hz sample speeds (similar to that used successfully on-sky at the LBT). Currently only the VisAO science camera is used for lab testing of MagAO, but this high level of measured performance (122 nm rms) promises even higher Strehls with our IR science cameras. On bright (R=8 mag) stars we should achieve very high Strehls (>70% at H) in the IR with the existing MagAO Clio2 (λ=1-5.3 μm) science camera/coronagraph or even higher (~98% Strehl) the Mid-IR (8-26 microns) with the existing BLINC/MIRAC4 science camera in the future. To eliminate non-common path vibrations, dispersions, and optical errors the VisAO science camera is fed by a common path advanced triplet ADC and is piggy-backed on the Pyramid WFS optical board itself. Also a high-speed shutter can be used to block periods of poor correction. The entire system passed CDR in June 2009, and we finished the closed-loop system level testing phase in December 2011. Final system acceptance (

  15. (30)Si mole fraction of a silicon material highly enriched in (28)Si determined by instrumental neutron activation analysis.

    Science.gov (United States)

    D'Agostino, Giancarlo; Di Luzio, Marco; Mana, Giovanni; Oddone, Massimo; Pramann, Axel; Prata, Michele

    2015-06-01

    The latest determination of the Avogadro constant, carried out by counting the atoms in a pure silicon crystal highly enriched in (28)Si, reached the target 2 × 10(-8) relative uncertainty required for the redefinition of the kilogram based on the Planck constant. The knowledge of the isotopic composition of the enriched silicon material is central; it is measured by isotope dilution mass spectrometry. In this work, an independent estimate of the (30)Si mole fraction was obtained by applying a relative measurement protocol based on Instrumental Neutron Activation Analysis. The amount of (30)Si isotope was determined by counting the 1266.1 keV γ-photons emitted during the radioactive decay of the radioisotope (31)Si produced via the neutron capture reaction (30)Si(n,γ)(31)Si. The x((30)Si) = 1.043(19) × 10(-6) mol mol(-1) is consistent with the value currently adopted by the International Avogadro Coordination.

  16. 30Si Mole Fraction of a Silicon Material Highly Enriched in 28Si Determined by Instrumental Neutron Activation Analysis

    CERN Document Server

    D'Agostino, Giancarlo; Mana, Giovanni; Oddone, Massimo; Pramann, Axel; Prata, Michele

    2016-01-01

    The latest determination of the Avogadro constant, carried out by counting the atoms in a pure silicon crystal highly enriched in 28Si, reached the target 2x10-8 relative uncertainty required for the redefinition of the kilogram based on the Planck constant. The knowledge of the isotopic composition of the enriched silicon material is central; it is measured by isotope dilution mass spectrometry. In this work, an independent estimate of the 30Si mole fraction was obtained by applying a relative measurement protocol based on Instrumental Neutron Activation Analysis. The amount of 30Si isotope was determined by counting the 1266.1 keV gamma-photons emitted during the radioactive decay of the radioisotope 31Si produced via the neutron capture reaction 30Si(n,gamma)31Si. The x(30Si) = 1.043(19)x10-6 mol mol-1 is consistent with the value currently adopted by the International Avogadro Coordination.

  17. Comment on a mathematical model for estimating biological damage caused by radiation. Whack-A-Mole model

    International Nuclear Information System (INIS)

    We propose a mathematical model, Whack-A-Mole (WAM) model which can estimate the biological effect caused by radiation. The WAM model assumes that the basic element is a cell and the number of cells increases or decreases due to response to stimulus, damage and recovery, cause by radiation and so on. WAM takes into account dose rate as an important physical quantity, which marks a fundamental difference from target theory or LQ model. WAM model reproduces various experimental data of mutation frequency induced by radiation, for example, mega-mouse project. Furthermore, we can predict unknown experimental results. From WAM model, it is learnt that the mutation frequency caused by radiation is not proportional to dose but also have saturation value. There is some possibility that the WAM model will drastically change risk estimation of radiation as it brings us different results from those of target theory or LQ model. (author)

  18. Automatic processing of atmospheric CO2 and CH4 mole fractions at the ICOS Atmosphere Thematic Centre

    Science.gov (United States)

    Hazan, Lynn; Tarniewicz, Jérôme; Ramonet, Michel; Laurent, Olivier; Abbaris, Amara

    2016-09-01

    The Integrated Carbon Observation System Atmosphere Thematic Centre (ICOS ATC) automatically processes atmospheric greenhouse gases mole fractions of data coming from sites of the ICOS network. Daily transferred raw data files are automatically processed and archived. Data are stored in the ICOS atmospheric database, the backbone of the system, which has been developed with an emphasis on the traceability of the data processing. Many data products, updated daily, explore the data through different angles to support the quality control of the dataset performed by the principal operators in charge of the instruments. The automatic processing includes calibration and water vapor corrections as described in the paper. The mole fractions calculated in near-real time (NRT) are automatically revaluated as soon as a new instrument calibration is processed or when the station supervisors perform quality control. By analyzing data from 11 sites, we determined that the average calibration corrections are equal to 1.7 ± 0.3 µmol mol-1 for CO2 and 2.8 ± 3 nmol mol-1 for CH4. These biases are important to correct to avoid artificial gradients between stations that could lead to error in flux estimates when using atmospheric inversion techniques. We also calculated that the average drift between two successive calibrations separated by 15 days amounts to ±0.05 µmol mol-1 and ±0.7 nmol mol-1 for CO2 and CH4, respectively. Outliers are generally due to errors in the instrument configuration and can be readily detected thanks to the data products provided by the ATC. Several developments are still ongoing to improve the processing, including automated spike detection and calculation of time-varying uncertainties.

  19. Spatial and temporal activity patterns of the free-living giant mole-rat (Fukomys mechowii, the largest social bathyergid.

    Directory of Open Access Journals (Sweden)

    Matěj Lövy

    Full Text Available Despite the considerable attention devoted to the biology of social species of African mole-rats (Bathyergidae, Rodentia, knowledge is lacking about their behaviour under natural conditions. We studied activity of the largest social bathyergid, the giant mole-rat Fukomys mechowii, in its natural habitat in Zambia using radio-telemetry. We radio-tracked six individuals during three continuous 72-h sessions. Five of these individuals, including a breeding male, belonged to a single family group; the remaining female was probably a solitary disperser. The non-breeders of the family were active (i.e. outside the nest 5.8 hours per 24h-day with the activity split into 6.5 short bouts. The activity was more concentrated in the night hours, when the animals also travelled longer distances from the nest. The breeding male spent only 3.2 hours per day outside the nest, utilizing less than 20% of the whole family home range. The dispersing female displayed a much different activity pattern than the family members. Her 8.0 hours of outside-nest activity per day were split into 4.6 bouts which were twice as long as in the family non-breeders. Her activity peak in the late afternoon coincided with the temperature maximum in the depth of 10 cm (roughly the depth of the foraging tunnels. Our results suggest that the breeding individuals (at least males contribute very little to the work of the family group. Nevertheless, the amount of an individual's activity and its daily pattern are probably flexible in this species and can be modified in response to actual environmental and social conditions.

  20. Reactive scattering of halogen molecules. [Angular and velocity distributions, stabilities 6. 8 to 17. 7 kcal/mole, FORTRAN

    Energy Technology Data Exchange (ETDEWEB)

    Valentini, J.J.

    1976-11-01

    A study of the endoergic, bimolecular reactions of F/sub 2/ with I/sub 2/, ICl, and HI in a crossed molecular beam experiment is described. The trihalogens IIF, ClIF, and HIF were directly observed as the products of these reactions. At high collision energies a second reactive channel producing IF becomes important. Product angular and velocity distributions show that this IF does not result from a four-center exchange reaction. Measured threshold energies for the formation of IIF, ClIF, and HIF yield lower bounds to the stabilities of these molecules, with respect to the separated atoms, of 69, 81, and 96 kcal/mole, respectively. Analysis of product center-of-mass angular distributions indicates that a slightly nonlinear approach is most effective in bringing about reaction to form the stable triatomic radical. Also described is a crossed molecular beam study of the Cl + Br/sub 2/ ..-->.. BrCl + Br reaction at collision energies from 6.8 to 17.7 kcal/mole. The results indicate that this reaction has the characteristics of an exoergic reaction on an attractive potential energy surface with early energy release. Reagent translational energy is very efficiently channeled into product internal energy. At high collision energy the reaction appears to approach the spectator stripping limit. Finally, a series of computer programs which can be used to carry out the requisite data analysis for crossed molecular beam reactive scattering experiments are described. These programs recover the reactive scattering center-of-mass flux distribution from the measured angular and velocity distributions of the products.

  1. The Mars Underground Mole (MUM): A Subsurface Penetration Device with Infrared Reflectance and Raman Spectroscopic Sensing Capability

    Science.gov (United States)

    Stoker, C. R.; Richter, L.; Smith, W. H.; Lemke, L. G.; Hammer, P.; Dalton, J. B.; Glass, B.; Zent, A.

    2003-01-01

    Searching for evidence of life on Mars will probably require access to the subsurface. The Martian surface is bathed in ultraviolet radiation which decomposes organic compounds, destroying possible evidence for life. Also, experiments performed by the Viking Landers imply the presence of several strongly oxidizing compounds at the Martian surface that may also play a role in destroying organic compounds near the surface. While liquid water is unstable on the Martian surface, and ice is unstable at the surface at low latitudes, recent results from the Mars Odyssey Gamma Ray Spectrometer experiment indicate that water ice is widely distributed near the surface under a thin cover of dry soil. Organic compounds created by an ancient Martian biosphere might be preserved in such ice-rich layers. Furthermore, accessing the subsurface provides a way to identify unique stratigraphy such as small-scale layering associated with lacustrine sediments. Subsurface access might also provide new insights into the Mars climate record that may be preserved in the Polar Layered Deposits. Recognizing the importance of accessing the subsurface of Mars to the future scientific exploration of the planet, the Mars Surveyor 2007 Science Definition Team called for drilling beneath the surface soils. Subsurface measurements are also cited as high priority in by MEPAG. Recognizing the importance of accessing the Martian subsurface to search for life, the European Space Agency has incorporated a small automated burrowing device called a subsurface penetrometer or Mole onto the Beagle 2 lander planned for 2003 launch. This device, called the Planetary Underground Tool (PLUTO), is a pointed slender cylinder 2 cm wide and 28 cm long equipped with a small sampling device at the pointed end that collects samples and brings them to the surface for analysis. Drawing on the PLUTO design, we are developing a larger Mole carrying sensors for identifying mineralogy, organic compounds, and water.

  2. The Role of NLRP 7 Gene in Hydatidiform Mole%NLRP7基因在葡萄胎发生中的作用

    Institute of Scientific and Technical Information of China (English)

    周薇

    2011-01-01

    Hydatidiform mole (HM) is a gestational trophoblastic disease (GrD) characterized by proliferation of the pregnancy-associated trophoblastic tissue. With the widespread use of ultrasound, early diagnosis and treatment of hydatidiform mole is possible, but the diagnosis is still based on histopathology. The treatment of hydatidiform mole is difficult, and the prognosis of this disease is not vary good especially in recurrent hydatidfform mole. The mechanism of hydatidiform mole remains unclear. Different type of mole and the wrong chromosome gene imprinting have been found in genetics. Recently, the nucleotide-binding domain, leucine rich containing, pyrin domain containing 7 (NLRP 7)gene is found to connected with recurrent hydatidfform mole. This article will have a review of NLRP7 gene in the role of hydatidiform mole.%葡萄胎(HM)是异常人类妊娠,以绒毛滋养细胞增生、间质水肿,同时缺乏胚胎发育或者异常的胚胎发育为特征,是一种滋养细胞疾病(GTD).超声的广泛使用使早期诊断和处理葡萄胎成为可能,但其确诊依据仍是组织学诊断;葡萄胎治疗有一定难度.且葡萄胎特别是复发性葡萄胎的预后不理想.葡萄胎的发生机制尚不明确,细胞遗传学研究发现葡萄胎组织染色体核型异常和基因印迹错误.最近对葡萄胎患者基因方面的研究发现,NLRP7基因与复发性葡萄胎存在相关性.就葡萄胎及其与NLRP7基因的研究进展综述.

  3. From Performance Optimization to Simulation-based Forensic Engineering - An extensive Approach for Dynamic Modeling of the HP³-Mole for InSight

    OpenAIRE

    Lichtenheldt, Roy

    2015-01-01

    In order to enable the InSight’s investigations of the Martian interior, the HP³-Mole has to hammer itself deeper below the surface of the red planet, than any other instrument before. In order to achieve this challenging goal, the dynamics of the impact driven locomotion as well as the mutual influence between the stroke cycle and the regolith need to be well understood. However it is not possible to observe the complex mechanism behaviour while the HP³-Mole is operating in Martian soil or t...

  4. Antecedentes e consequencia da atitude frente ao anuncio nos idosos

    OpenAIRE

    Sanchez, Javier; Estrada, Marta; Moliner, Miguel Angel; Fandos, Juan Carlos

    2011-01-01

    A importancia sócio-economica adquirida nos ultimos anos na Espanha e em outros paises europeus pelo emergente mercado dos idosos toma necessaria o estudo de suas particularidades como consumidores. As mudanças ocorridas durante o proceso do envelhecimento exercem uma influencia na percepçao do fenómeno publicitario e, par conseguinte, na atitude manifestada frente ao anúcio. o estudo nos idosos dos antecedentes da atitude frente ao anuncio e suas consequencias no contexto do modelo de mediaç...

  5. The Robo-AO automated intelligent queue system

    CERN Document Server

    Riddle, Reed L; Papadopoulos, Athanasios; Baranec, Christoph; Law, Nicholas M

    2014-01-01

    Robo-AO is the first automated laser adaptive optics instrument. In just its second year of scientific operations, it has completed the largest adaptive optics surveys to date, each comprising thousands of targets. Robo-AO uses a fully automated queue scheduling system that selects targets based on criteria entered on a per observing program or per target basis, and includes the ability to coordinate with US Strategic Command automatically to avoid lasing space assets. This enables Robo-AO to select among thousands of targets at a time, and achieve an average observation rate of approximately 20 targets per hour.

  6. An efficient algorithm for generating AoA networks

    Directory of Open Access Journals (Sweden)

    Nasser Eddine Mouhoub

    2012-01-01

    Full Text Available The activities, in project scheduling, can be represented graphically in two different ways, by either assigning the activities to the nodes 'AoN directed acyclic graph (dag or to the arcs 'AoA dag. In this paper, a new algorithm is proposed for generating, for a given project scheduling problem, an Activity-on-Arc dag starting from the Activity-on-Node dag using the concepts of line graphs of graphs.

  7. Identification of patients with persistent trophoblastic disease after complete hydatidiform mole by using a normal 24-hour urine hCG regression curve

    NARCIS (Netherlands)

    Cromvoirt, S.M. van; Thomas, C.M.G.; Quinn, M.A.; McNally, O.M.; Bekkers, R.L.M.

    2014-01-01

    OBJECTIVE: The aim of this study was to establish a reference 24-hour urine human chorionic gonadotropin (hCG) regression curve in patients with complete hydatidiform mole (CHM) as diagnostic tool in the prediction of persistent trophoblastic disease (PTD). METHODS: From 2004 to 2011, 312 cases suit

  8. Size variation in Tachyoryctes splendens (East African mole-rat) and its implications for late Quaternary temperature change in equatorial East Africa

    Science.gov (United States)

    Faith, J. Tyler; Patterson, David B.; Blegen, Nick; O'Neill, Chris J.; Marean, Curtis W.; Peppe, Daniel J.; Tryon, Christian A.

    2016-05-01

    This study develops a new proxy for Quaternary temperature change in tropical Africa through analysis of size variation in East African mole-rat (Tachyoryctes splendens). In modern mole-rats, mandibular alveolar length is unrelated to annual precipitation, precipitation seasonality, temperature seasonality, or primary productivity. However, it is inversely correlated with mean annual temperature, in agreement with Bergmann's rule. This relationship is observed at temperatures below ˜17.3 °C, but not at higher temperatures. We apply these observations to late Quaternary mole-rats from Wakondo (˜100 ka) and Kisaaka (˜50 ka) in the Lake Victoria region and Enkapune ya Muto (EYM; ˜7.2-3.2 ka) in Kenya's central rift. The Lake Victoria mole-rats are larger than expected for populations from warm climates typical of the area today, implying cooler temperatures in the past. The magnitude of temperature decline needed to drive the size shift is substantial (˜4-6 °C), similar in magnitude to the degree of change between the Last Glacial Maximum and Holocene, but is consistent with regional temperature records and with scenarios linking equatorial African temperature to northern hemisphere summer insolation. Size changes through time at EYM indicate that rising temperatures during the middle Holocene accompanied and potentially contributed to a decline in Lake Naivasha and expansion of grassland vegetation.

  9. Final report of CCQM-K129 Measurement of Mole Fractions of Cu, In, Ga and Se in Cu(In,Ga)Se2 Films

    Science.gov (United States)

    Kim, K. J.; Kim, A. S.; Jang, J. S.; Suh, J. K.; Wirth, T.; Unger, W.; Hodoroaba, V.-D.; Araujo, J. R.; Archanjo, B. S.; Galhardo, C. E.; Damasceno, J.; Achete, C. A.; Wang, H.; Wang, M.; Bennett, J.; Simon, D.; Kurokawa, A.; Terauchi, S.; Fujimoto, T.; Streeck, C.; Beckhoff, B.; Spencer, S.; Shard, A.

    2016-01-01

    CCQM key comparison K-129 for the quantitative analysis of Cu(In,Ga)Se2 (CIGS) films has been performed by the Surface Analysis Working Group (SAWG) of the Consultative Committee for Amount of Substance (CCQM). The objective of this key comparison is to compare the equivalency of the National Metrology Institutes (NMIs) and Designated Institutes (DIs) for the measurement of mole fractions of Cu, In, Ga and Se in a thin CIGS film. The measurand of this key comparison is the average mole fractions of Cu, In, Ga and Se of a test CIGS alloy film in the unit of mole fraction (mol/mol). Mole fraction with the metrological unit of % mol/mol can be practically converted to atomic fraction with the unit of at %. In this key comparison, a CIGS film with certified mole fractions was supplied as a reference specimen to determine the relative sensitivity factors (RSFs) of Cu, In, Ga and Se. The mole fractions of the reference specimen were certified by isotope dilution - inductively coupled plasma/mass spectrometry (ID-ICP/MS). A total number counting (TNC) method was recommended as a method to determine the signal intensities of the constituent elements acquired in the depth profiles by Secondary Ion Mass Spectrometry (SIMS), X-ray Photoelectron Spectroscopy (XPS) and Auger Electron Spectroscopy (AES). Seven NMIs and one DI participated in this key comparison. The mole fractions of the CIGS films were measured by depth profiling based-SIMS, AES and XPS. In this key comparison, the average degrees of equivalence uncertainties for Cu, In, Ga and Se are 0.0093 mol/mol, 0.0123 mol/mol, 0.0047 mol/mol and 0.0228 mol/mol, respectively. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  10. Quitosana no controle pós-colheita da podridão mole em caqui 'rama forte' Chitosan on the postharvest control of soft rot in 'rama forte' persimmon

    Directory of Open Access Journals (Sweden)

    Patrícia Cia

    2010-01-01

    Full Text Available Este trabalho objetivou avaliar o efeito da quitosana, aliada ao processo de destanização, no controle de Rhizopus stolonifer em caqui 'Rama Forte' e sobre o crescimento micelial do fungo in vitro. Caquis foram submetidos ao processo de destanização com CO2 (70% / 18 horas, em tambores herméticos, sendo em seguida submetidos à inoculação com suspensão de esporos de R. stolonifer (3x10(5 esporos mL-1. Após inoculação, os frutos permaneceram por 2 horas a 25 °C, quando foram imersos em quitosana (0; 0,5; 1,0; 1,5 e 2,0%, por 1 minuto. Os frutos foram mantidos a 25 °C / 80% UR e avaliados quanto à severidade e incidência da podridão mole, durante cinco dias. Após o período de armazenamento, avaliaram-se a coloração de casca, a firmeza e o índice de adstringência. In vitro, avaliou-se o crescimento micelial em placas contendo meio BDA incorporado com quitosana ou ácido cítrico. Os resultados mostraram que a quitosana, a 1,5%, reduz a severidade e a incidência da podridão mole em caquis e não influencia no processo de perda de adstringência, firmeza e na coloração de casca. In vitro, a quitosana inibe completamente o crescimento micelial de R. stolonifer, em concentração tão baixa quanto 0,5%.The objective of this research was to evaluate the effect of chitosan in addition to de-astringency process on the control of Rhizopus stolonifer in 'Rama Forte' persimmon and on in vitro mycelial growth. Persimmon were submitted to de-astringency process using CO2 (70% / 18 h, in hermetic chambers. Next, fruit were inoculated through subcuticular injections of a R. stolonifer spore suspension (3x10(5 spore mL-1 and 2 hours later at 25 °C immersed into chitosan (0, 0.5, 1.0, 1.5, and 2.0%, for 1 min. Fruit were stored at 25 °C / 80% RH, and checked for rot severity and incidence of soft rot, during 5-days of storage. After storage the skin color, firmness and astringency index were evaluated in persimmons. In vitro, mycelial

  11. Recognition and Release of Nalidixic Acid Using Uniformly Sized -Imprinted Nanospheres: Methacrylic Acid to Methyl Methacrylate Different Mole Ratios

    Directory of Open Access Journals (Sweden)

    Mehdi Forouzani

    2013-01-01

    Full Text Available In the presence of imprinting molecules of Nalidixic acid, uniformly sized molecularly imprinted polymers (MIPs in nanometer range were synthesized. The MIPs were successfully prepared by precipitation polymerization using methacrylic acid (MAA and methyl methacrylate (MMA as functional monomers at different mole ratios. The effect of combination of MAA-to-MMA on the morphology, binding, recognition and release behaviors of the final particles were studied. The produced polymers were characterized by differential scanning calorimetry and their morphology was precisely examined by scanning electron microscopy. We obtained very uniform imprinted nanospheres with diameter of 120- 180 nm. Among the MIP nanospheres the MIPs using combination of MAA and MMA showed nanospheres with lowest mean diameter (120 nm and the highest selectivity factor (9.7. The adsorption properties of Nalidixic acid in acetonitrile for imprinted nanospheres were evaluated by equilibrium rebinding experiments. Results from binding experiments proved that MIPs exhibit specific affinity to Nalidixic acid in contrast to control polymers and this performance was affected by pH of loading solution and. Moreover, release experiments showed the controlled release of Nalidixic acid in longtime period. The loaded Nalidixic acid was released from the imprinted nanospheres within the 140 h.

  12. Raman Scattering and t-Phase Lattice Vibration of 3% (mole fraction) Y2O3-ZrO2

    Institute of Scientific and Technical Information of China (English)

    Xinglun TANG; Xiuhua ZHENG

    2004-01-01

    The Raman spectra of 3% (mole fraction) Y2O3-ZrO2 (3Y) are obtained at different temperature from 77 K to 853 K. The results show that 260 cm-1 Eg and 460 cm-1 Eg modes on the spectra shift toward lower wave number with the increase of temperature; meanwhile, the continuity of the Half Width at Half Maximum (HWHM) and wave number (frequency) of Raman bands are broken and t-phase only partially transforms to m-phase at 523 K. Based on the experimental results, this paper discusses the t-phase lattice vibration of 3Y and presents the images of vibration displacement of six Raman-active modes for t-phase of ZrO2. The analysis indicates that there are diversities existing in the displacement of the atomic vibration of Raman-active modes because of their different symmetries at various temperature, which leads to the different change tendencies of Raman bands. Furthermore, the abrupt changes of some Raman-active modes indicating the atomic displacement are assumed to be the condensations of phonon modes in the t→m phase transition.

  13. Effect of radiolysis on leachability of plutonium and americium from 76-101 glass. [Glass containing 2 mole % plutonium

    Energy Technology Data Exchange (ETDEWEB)

    Nash, K.L.; Fried, S.; Friedman, A.M.; Susak, N.; Rickert, P.; Sullivan, J.C.; Karim, D.P.; Lam, D.J.

    1982-01-01

    One aspect of the leachability of actinide-bearing glass which has not been adequately addressed is the effect of radiolysis of the system (glass-water) on the amount of actinides liberated from the glass. In the present study, we have investigated the leaching of plutonium and americium from 76-101 glass samples (containing 2 mole % plutonium) in the presence of a one megaRad/hour gamma-radiation field. The presence of the radiation field was found to increase the leaching rate of both plutonium and americium by a factor of five. Speciation studies of the plutonium in the leachate indicate that the plutonium is present predominantly in the higher oxidation states, Pu(V) and Pu(VI) and that it is significantly associated with colloidal particles. Examination of the glass surfaces with x-ray photoemission spectroscopy, XPS, both before and after leaching was carried out; these studies showed lower surface concentrations of plutonium in the samples of glass leached in the radiation field. 1 figure, 3 tables.

  14. Seasonality and interannual variability of CH4 fluxes from the eastern Amazon Basin inferred from atmospheric mole fraction profiles

    Science.gov (United States)

    Basso, Luana S.; Gatti, Luciana V.; Gloor, Manuel; Miller, John B.; Domingues, Lucas G.; Correia, Caio S. C.; Borges, Viviane F.

    2016-01-01

    The Amazon Basin is an important region for global CH4 emissions. It hosts the largest area of humid tropical forests, and around 20% of this area is seasonally flooded. In a warming climate it is possible that CH4 emissions from the Amazon will increase both as a result of increased temperatures and precipitation. To examine if there are indications of first signs of such changes we present here a 13 year (2000-2013) record of regularly measured vertical CH4 mole fraction profiles above the eastern Brazilian Amazon, sensitive to fluxes from the region upwind of Santarém (SAN), between SAN and the Atlantic coast. Using a simple mass balance approach, we find substantial CH4 emissions with an annual average flux of 52.8 ± 6.8 mg CH4 m-2 d-1 over an area of approximately 1 × 106 km2. Fluxes are highest in two periods of the year: in the beginning of the wet season and during the dry season. Using a CO:CH4 emission factor estimated from the profile data, we estimated a contribution of biomass burning of around 15% to the total flux in the dry season, indicating that biogenic emissions dominate the CH4 flux. This 13 year record shows that CH4 emissions upwind of SAN varied over the years, with highest emissions in 2008 (around 25% higher than in 2007), mainly during the wet season, representing 19% of the observed global increase in this year.

  15. Twin pregnancy and partial hydatidiform mole following in vitro fertilization and embryos transfer: a novel case of placental mosaicism

    Institute of Scientific and Technical Information of China (English)

    SUN Cheng-juan; ZHAO You-ping; YU Song; FAN Ling; WU Qing-qing; LI Guang-hui; ZHANG Wei-yuan

    2012-01-01

    Twin pregnancy with mosaic partial hydatidiform mole (PHM) and survival of two healthy fetuses following in vitro fertilization and embryos transfer (IVF-ET) is a rare situation and is considered a challenge for management.A 32-year-old Chinese woman conceived twin pregnancy following IVF-ET.At 22 weeks' gestation,an additional intrauterine echogenic mass with features of PHM were shown by successive ultrasound examinations.At 35 weeks'gestation,two live male infants and two placentas were delivered by caesarean section (CS).Histologic examination of the abnormal placenta confirmed mosaic PHM.Genetic study showed the abnormal placental mosaicism (expressed in molar-69XXY and normal vili-46XY),co-existing with a hypospadia new-born (46XY) in one amniotic sac.However,the other one was normal.Serial serum β-hCG levels showed a declining trend and serum 3-human chorionic gonadotropin (hCG) were undetectable at 6 months after delivery.The case demonstrated that it is possible to prolonged gestation by PHM under close surveillance during the entire pregnancy.

  16. Performance of N2O and CO analyser for high-precision measurements of atmospheric mole fractions

    Science.gov (United States)

    Stanley, Kieran; O'Doherty, Simon

    2016-04-01

    N2O and CO are two important biogenic and anthropogenic greenhouse gases. N2O has a global warming potential approximately 300 times greater than CO2 on a per-molecule basis over a 100 year time horizon and is one of the most important factors affecting stratospheric ozone depletion. CO is a key gas in tropospheric photochemistry, constraining OH concentrations in the unpolluted atmosphere and the oxidising capacity in the troposphere. Due to the importance of N2O and CO as greenhouse and ozone depleting gases, precise high-frequency measurements of the two gases are necessary to better understand atmospheric mixing ratios. A number of different methods are available to measure the two gases, mainly based on chromatographic and reduction methods. The chromatographic method used to quantify atmospheric N2O mole fractions has not yet reached the WMO compatibility goal of ± 0.1 ppb. Over the past few years, new analytical techniques based on optical spectroscopy have been developed and become commercially available, providing near-real time data to high precision. In this presentation, we will give an overview of the performance of an Off Axis-Integrated Cavity Output Spectroscopy analyser with improvements made to temperature and pressure stability by the Scripps Institute of Oceanography. Results of the continuous repeatability measurement (referred to as precision by the manufacturers), short- and long-term repeatability, drift, temperature dependence, instrument linearity and H2O sensitivity will be presented.

  17. Second generation Robo-AO instruments and systems

    CERN Document Server

    Baranec, Christoph; Law, Nicholas M; Chun, Mark R; Lu, Jessica R; Connelley, Michael S; Hall, Donald; Atkinson, Dani; Jacobson, Shane

    2014-01-01

    The prototype Robo-AO system at the Palomar Observatory 1.5-m telescope is the world's first fully automated laser adaptive optics instrument. Scientific operations commenced in June 2012 and more than 12,000 observations have since been performed at the ~0.12" visible-light diffraction limit. Two new infrared cameras providing high-speed tip-tilt sensing and a 2' field-of-view will be integrated in 2014. In addition to a Robo-AO clone for the 2-m IGO and the natural guide star variant KAPAO at the 1-m Table Mountain telescope, a second generation of facility-class Robo-AO systems are in development for the 2.2-m University of Hawai'i and 3-m IRTF telescopes which will provide higher Strehl ratios, sharper imaging, ~0.07", and correction to {\\lambda} = 400 nm.

  18. Uma leitura da Carta ao pai de Kafka

    Directory of Open Access Journals (Sweden)

    Filipe Pereirinha

    2015-02-01

    Full Text Available ResumoPode uma carta chegar ao seu destino mesmo quando não é enviada? A Carta ao pai, de Kakfa, serve-nos aqui de balão de ensaio para esboçar uma possível resposta a esta questão. Não se trata, porém, de ler esta carta como se ela traduzisse finalmente, ao pé da letra, o conflito edipiano entre Kafka e o seu pai, mas antes de ver neste suposto conflito – e seus impasses – o limiar de outra coisa bem mais real. Palavras-chave: Kafka; Lacan; letra; sintoma; realFilipe Pereirinha é membro da Antena do Campo Freudiano (ACF - Portugal, associação psicanalítica ligada à New Lacanian School (NLS e à Associação Mundial de Psicanálise (AMP. O seu encontro com a psicanálise de orientação lacaniana aconteceu durante a licenciatura em Filosofia, na Universidade Nova de Lisboa (UNL, e foi determinante no rumo posterior dos seus estudos, tanto ao nível do mestrado em Filosofia, com uma tese sobre o desejo em Deleuze e Lacan, como ao nível do doutoramento em Filosofia Moderna e Contemporânea, com uma tese sobre a questão do sujeito em Lacan. Foi Professor e Investigador na Universidade Lusófona (ULHT, onde esteve ligado, em particular, desde a sua criação, ao Centro de Estudos de Psicanálise (CEP. Tem vários artigos publicados em livros e revistas, nomeadamente em Portugal, França e Brasil. Destacam-se os livros Psicanálise & Arredores e Uma Pedra no Caminho (no prelo. Está em preparação uma coletânea com os artigos mais recentes.

  19. Atypical Mole (Atypical Nevus)

    Science.gov (United States)

    ... melanoma). Remember the ABCDEs of melanoma lesions: A - Asymmetry: One half of the lesion does not mirror ... York: Mosby, 2003. Last Updated: 22 Dec 2008 Information for other ages: Child Teen Table of Contents: ...

  20. LGS AO Science Impact: Present and Future Perspectives

    OpenAIRE

    Liu, Michael C.

    2008-01-01

    The recent advent of laser guide star adaptive optics (LGS AO) on the largest ground-based telescopes has enabled a wide range of high angular resolution science, previously infeasible from ground-based and/or space-based observatories. As a result, scientific productivity with LGS has seen enormous growth in the last few years, with a factor of ~10 leap in publication rate compared to the first decade of operation. Of the 54 refereed science papers to date from LGS AO, half have been publish...

  1. All About Portugal - Website dedicado ao turismo externo em Portugal

    OpenAIRE

    Martins, Rui Manuel da Silva

    2015-01-01

    Grande parte do tráfego online tem origem em páginas de resultados de motores de de pesquisa. Estes constituem hoje uma ferramenta fundamental de que os turistas se socorrem para pesquisar e filtrar a informação necessária ao planeamento das suas viagens, sendo, por isso, bastante tidos em conta pelas entidades ligadas ao turismo no momento da definição das suas estratégias de marketing. No presente documento é descrita a investigação feita em torno do modo de funcionamento ...

  2. Long-term analysis of carbon dioxide and methane column-averaged mole fractions retrieved from SCIAMACHY

    Directory of Open Access Journals (Sweden)

    O. Schneising

    2011-03-01

    Full Text Available Carbon dioxide (CO2 and methane (CH4 are the two most important anthropogenic greenhouse gases contributing to global climate change. SCIAMACHY onboard ENVISAT (launch 2002 was the first and is now with TANSO onboard GOSAT (launch 2009 one of only two satellite instruments currently in space whose measurements are sensitive to CO2 and CH4 concentration changes in the lowest atmospheric layers where the variability due to sources and sinks is largest.

    We present long-term SCIAMACHY retrievals (2003–2009 of column-averaged dry air mole fractions of both gases (denoted XCO2 and XCH4 derived from absorption bands in the near-infrared/shortwave-infrared (NIR/SWIR spectral region focusing on large-scale features. The results are obtained using an upgraded version (v2 of the retrieval algorithm WFM-DOAS including several improvements, while simultaneously maintaining its high processing speed. The retrieved mole fractions are compared to global model simulations (CarbonTracker XCO2 and TM5 XCH4 being optimised by assimilating highly accurate surface measurements from the NOAA/ESRL network and taking the SCIAMACHY averaging kernels into account. The comparisons address seasonal variations and long-term characteristics.

    The steady increase of atmospheric carbon dioxide primarily caused by the burning of fossil fuels can be clearly observed with SCIAMACHY globally. The retrieved global annual mean XCO2 increase agrees with CarbonTracker within the error bars (1.80±0.13 ppm yr−1 compared to 1.81±0.09 ppm yr−1. The amplitude of the XCO2 seasonal cycle as retrieved by SCIAMACHY, which is 4.3±0.2 ppm for the Northern Hemisphere and 1.4±0.2 ppm for the Southern Hemisphere, is on average about 1 ppm larger than for CarbonTracker.

    An investigation of the boreal forest carbon uptake during the

  3. Long-term analysis of carbon dioxide and methane column-averaged mole fractions retrieved from SCIAMACHY

    Directory of Open Access Journals (Sweden)

    O. Schneising

    2010-11-01

    Full Text Available Carbon dioxide (CO2 and methane (CH4 are the two most important anthropogenic greenhouse gases contributing to global climate change. SCIAMACHY onboard ENVISAT (launch 2002 was the first and is now together with TANSO onboard GOSAT (launch 2009 the only satellite instrument currently in space whose measurements are sensitive to CO2 and CH4 concentration changes in the lowest atmospheric layers where the variability due to sources and sinks is largest.

    We present long-term SCIAMACHY retrievals (2003–2009 of column-averaged mole fractions of both gases (denoted XCO2 and XCH4 derived from absorption bands in the near-infrared/shortwave-infrared (NIR/SWIR spectral region focusing on large-scale features. The results are obtained using an upgraded version (v2 of the retrieval algorithm WFM-DOAS including several improvements, while simultaneously maintaining its high processing speed. The retrieved mole fractions are compared to global model simulations (CarbonTracker XCO2 and TM5 XCH4 being optimised by assimilating highly accurate surface measurements from the NOAA/ESRL network and taking the SCIAMACHY averaging kernels into account. The comparisons address seasonal variations and long-term characteristics.

    The steady increase of atmospheric carbon dioxide primarily caused by the burning of fossil fuels can be clearly observed with SCIAMACHY globally. The retrieved annual mean XCO2 increase over both hemispheres agrees with CarbonTracker within the error bars but is on average somewhat smaller (1.8 ppm yr−1 compared to 1.9 ppm yr−1. The amplitude of the XCO2 seasonal cycle as retrieved by SCIAMACHY, which is 4.3 ppm for the Northern Hemisphere and 1.4 ppm for the Southern Hemisphere, is on average about 1 ppm larger than for CarbonTracker.

    An investigation of the boreal forest carbon

  4. Non-Breeding Eusocial Mole-Rats Produce Viable Sperm--Spermiogram and Functional Testicular Morphology of Fukomys anselli.

    Directory of Open Access Journals (Sweden)

    Angelica Garcia Montero

    Full Text Available Ansell's mole-rats (Fukomys anselli are subterranean rodents living in families composed of about 20 members with a single breeding pair and their non-breeding offspring. Most of them remain with their parents for their lifetime and help to maintain and defend the natal burrow system, forage, and care for younger siblings. Since incest avoidance is based on individual recognition (and not on social suppression we expect that non-breeders produce viable sperm spontaneously. We compared the sperm of breeding and non-breeding males, obtained by electroejaculation and found no significant differences in sperm parameters between both groups. Here, we used electroejaculation to obtain semen for the first time in a subterranean mammal. Spermiogram analysis revealed no significant differences in sperm parameters between breeders and non-breeders. We found significantly larger testes (measured on autopsies and on living animals per ultrasonography of breeders compared to non-breeders (with body mass having a significant effect. There were no marked histological differences between breeding and non-breeding males, and the relative area occupied by Leydig cells and seminiferous tubules on histological sections, respectively, was not significantly different between both groups. The seminiferous epithelium and to a lesser degree the interstitial testicular tissue are characterized by lesions (vacuolar degenerations, however, this feature does not hinder fertilization even in advanced stages of life. The continuous production of viable sperm also in sexually abstinent non-breeders might be best understood in light of the mating and social system of Fukomys anselli, and the potential to found a new family following an unpredictable and rare encounter with an unfamiliar female ("provoked or induced dispersal". Apparently, the non-breeders do not reproduce because they do not copulate but not because they would be physiologically infertile. The significantly

  5. Non-Breeding Eusocial Mole-Rats Produce Viable Sperm—Spermiogram and Functional Testicular Morphology of Fukomys anselli

    Science.gov (United States)

    Garcia Montero, Angelica; Vole, Christiane; Burda, Hynek; Malkemper, Erich Pascal; Holtze, Susanne; Morhart, Michaela; Saragusty, Joseph; Hildebrandt, Thomas B.; Begall, Sabine

    2016-01-01

    Ansell’s mole-rats (Fukomys anselli) are subterranean rodents living in families composed of about 20 members with a single breeding pair and their non-breeding offspring. Most of them remain with their parents for their lifetime and help to maintain and defend the natal burrow system, forage, and care for younger siblings. Since incest avoidance is based on individual recognition (and not on social suppression) we expect that non-breeders produce viable sperm spontaneously. We compared the sperm of breeding and non-breeding males, obtained by electroejaculation and found no significant differences in sperm parameters between both groups. Here, we used electroejaculation to obtain semen for the first time in a subterranean mammal. Spermiogram analysis revealed no significant differences in sperm parameters between breeders and non-breeders. We found significantly larger testes (measured on autopsies and on living animals per ultrasonography) of breeders compared to non-breeders (with body mass having a significant effect). There were no marked histological differences between breeding and non-breeding males, and the relative area occupied by Leydig cells and seminiferous tubules on histological sections, respectively, was not significantly different between both groups. The seminiferous epithelium and to a lesser degree the interstitial testicular tissue are characterized by lesions (vacuolar degenerations), however, this feature does not hinder fertilization even in advanced stages of life. The continuous production of viable sperm also in sexually abstinent non-breeders might be best understood in light of the mating and social system of Fukomys anselli, and the potential to found a new family following an unpredictable and rare encounter with an unfamiliar female (“provoked or induced dispersal”). Apparently, the non-breeders do not reproduce because they do not copulate but not because they would be physiologically infertile. The significantly increased

  6. Immunohistochemical characterization of the chemosensory pulmonary neuroepithelial bodies in the naked mole-rat reveals a unique adaptive phenotype.

    Directory of Open Access Journals (Sweden)

    Jie Pan

    Full Text Available The pulmonary neuroepithelial bodies (NEBs constitute polymodal airway chemosensors for monitoring and signaling ambient gas concentrations (pO2, pCO2/H+ via complex innervation to the brain stem controlling breathing. NEBs produce the bioactive amine, serotonin (5-HT, and a variety of peptides with multiple effects on lung physiology and other organ systems. NEBs in mammals appear prominent and numerous during fetal and neonatal periods, and decline in the post-natal period suggesting an important role during perinatal adaptation. The naked mole-rat (NMR, Heterocephalus glaber, has adapted to the extreme environmental conditions of living in subterranean burrows in large colonies (up to 300 colony mates. The crowded, unventilated burrows are environments of severe hypoxia and hypercapnia. However, NMRs adjust readily to above ground conditions. The chemosensory NEBs of this species were characterized and compared to those of the conventional Wistar rat (WR to identify similarities and differences that could explain the NMR's adaptability to environments. A multilabel immunohistochemical analysis combined with confocal microscopy revealed that the expression patterns of amine, peptide, neuroendocrine, innervation markers and chemosensor component proteins in NEBs of NMR were similar to that of WR. However, we found the following differences: 1 NEBs in both neonatal and adult NMR lungs were significantly larger and more numerous as compared to WR; 2 NEBs in NMR had a more variable compact cell organization and exhibited significant differences in the expression of adhesion proteins; 3 NMR NEBs showed a significantly greater ratio of 5-HT positive cells with an abundance of 5-HT; 4 NEBs in NMR expressed the proliferating cell nuclear antigen (PCNA and the neurogenic gene (MASH1 indicating active proliferation and a state of persistent differentiation. Taken together our findings suggest that NEBs in lungs of NMR are in a hyperactive, functional

  7. Non-Breeding Eusocial Mole-Rats Produce Viable Sperm--Spermiogram and Functional Testicular Morphology of Fukomys anselli.

    Science.gov (United States)

    Garcia Montero, Angelica; Vole, Christiane; Burda, Hynek; Malkemper, Erich Pascal; Holtze, Susanne; Morhart, Michaela; Saragusty, Joseph; Hildebrandt, Thomas B; Begall, Sabine

    2016-01-01

    Ansell's mole-rats (Fukomys anselli) are subterranean rodents living in families composed of about 20 members with a single breeding pair and their non-breeding offspring. Most of them remain with their parents for their lifetime and help to maintain and defend the natal burrow system, forage, and care for younger siblings. Since incest avoidance is based on individual recognition (and not on social suppression) we expect that non-breeders produce viable sperm spontaneously. We compared the sperm of breeding and non-breeding males, obtained by electroejaculation and found no significant differences in sperm parameters between both groups. Here, we used electroejaculation to obtain semen for the first time in a subterranean mammal. Spermiogram analysis revealed no significant differences in sperm parameters between breeders and non-breeders. We found significantly larger testes (measured on autopsies and on living animals per ultrasonography) of breeders compared to non-breeders (with body mass having a significant effect). There were no marked histological differences between breeding and non-breeding males, and the relative area occupied by Leydig cells and seminiferous tubules on histological sections, respectively, was not significantly different between both groups. The seminiferous epithelium and to a lesser degree the interstitial testicular tissue are characterized by lesions (vacuolar degenerations), however, this feature does not hinder fertilization even in advanced stages of life. The continuous production of viable sperm also in sexually abstinent non-breeders might be best understood in light of the mating and social system of Fukomys anselli, and the potential to found a new family following an unpredictable and rare encounter with an unfamiliar female ("provoked or induced dispersal"). Apparently, the non-breeders do not reproduce because they do not copulate but not because they would be physiologically infertile. The significantly increased testes

  8. Non-Breeding Eusocial Mole-Rats Produce Viable Sperm--Spermiogram and Functional Testicular Morphology of Fukomys anselli.

    Science.gov (United States)

    Garcia Montero, Angelica; Vole, Christiane; Burda, Hynek; Malkemper, Erich Pascal; Holtze, Susanne; Morhart, Michaela; Saragusty, Joseph; Hildebrandt, Thomas B; Begall, Sabine

    2016-01-01

    Ansell's mole-rats (Fukomys anselli) are subterranean rodents living in families composed of about 20 members with a single breeding pair and their non-breeding offspring. Most of them remain with their parents for their lifetime and help to maintain and defend the natal burrow system, forage, and care for younger siblings. Since incest avoidance is based on individual recognition (and not on social suppression) we expect that non-breeders produce viable sperm spontaneously. We compared the sperm of breeding and non-breeding males, obtained by electroejaculation and found no significant differences in sperm parameters between both groups. Here, we used electroejaculation to obtain semen for the first time in a subterranean mammal. Spermiogram analysis revealed no significant differences in sperm parameters between breeders and non-breeders. We found significantly larger testes (measured on autopsies and on living animals per ultrasonography) of breeders compared to non-breeders (with body mass having a significant effect). There were no marked histological differences between breeding and non-breeding males, and the relative area occupied by Leydig cells and seminiferous tubules on histological sections, respectively, was not significantly different between both groups. The seminiferous epithelium and to a lesser degree the interstitial testicular tissue are characterized by lesions (vacuolar degenerations), however, this feature does not hinder fertilization even in advanced stages of life. The continuous production of viable sperm also in sexually abstinent non-breeders might be best understood in light of the mating and social system of Fukomys anselli, and the potential to found a new family following an unpredictable and rare encounter with an unfamiliar female ("provoked or induced dispersal"). Apparently, the non-breeders do not reproduce because they do not copulate but not because they would be physiologically infertile. The significantly increased testes

  9. Seasonality and interannual variability of CH4 fluxes from the eastern Amazon Basin inferred from atmospheric mole fraction profiles

    Science.gov (United States)

    Gatti, Luciana V.; Gloor, Manuel; Miller, John B.; Domingues, Lucas G.; Correia, Caio S. C.; Borges, Viviane F.

    2016-01-01

    Abstract The Amazon Basin is an important region for global CH4 emissions. It hosts the largest area of humid tropical forests, and around 20% of this area is seasonally flooded. In a warming climate it is possible that CH4 emissions from the Amazon will increase both as a result of increased temperatures and precipitation. To examine if there are indications of first signs of such changes we present here a 13 year (2000–2013) record of regularly measured vertical CH4 mole fraction profiles above the eastern Brazilian Amazon, sensitive to fluxes from the region upwind of Santarém (SAN), between SAN and the Atlantic coast. Using a simple mass balance approach, we find substantial CH4 emissions with an annual average flux of 52.8 ± 6.8 mg CH4 m−2 d−1 over an area of approximately 1 × 106 km2. Fluxes are highest in two periods of the year: in the beginning of the wet season and during the dry season. Using a CO:CH4 emission factor estimated from the profile data, we estimated a contribution of biomass burning of around 15% to the total flux in the dry season, indicating that biogenic emissions dominate the CH4 flux. This 13 year record shows that CH4 emissions upwind of SAN varied over the years, with highest emissions in 2008 (around 25% higher than in 2007), mainly during the wet season, representing 19% of the observed global increase in this year.

  10. Defective pericyte recruitment of villous stromal vessels as the possible etiologic cause of hydropic change in complete hydatidiform mole.

    Directory of Open Access Journals (Sweden)

    Kyu Rae Kim

    Full Text Available The pathogenetic mechanism underlying the hydropic change in complete hydatidiform moles (CHMs is poorly understood. A growing body of data suggests that pericytes play a role in vascular maturation. Since maturation of villous stromal vessels in CHMs is markedly impaired at early stages, we postulated that a defect in pericytes around stromal vessels in chorionic villi might cause vascular immaturity and subsequent hydropic change. To investigate this, we examined several markers of pericytes, namely, α-smooth muscle actin (α-SMA, platelet-derived growth factor receptor-β (PDGFR-β, and desmin, in 61 normally developing placentas and 41 CHMs with gestational ages of 4-12 weeks. The ultrastructure of villous stromal vessels was also examined. Mature blood vessels from normal placentas show patent vascular lumens and formed hematopoietic components in the villous stroma. α-SMA and PDGFR-β expression in the villous stroma gradually increased and extended from the chorionic plate to peripheral villous branches. The labeled cells formed a reticular network in the villous stroma and, after week 7, encircled villous stromal vessels. In comparison, α-SMA and PDGFR-β expression in the villous stroma and stromal vessels of CHMs was significantly lower (p<0.05. Ultrastructurally, endothelial cells in villous stromal vessels in normal placentas were consistently attached by pericytes after week 7 when the vessels formed distinct lumen, whereas the villous stromal vessels in CHMs consisted of linear chains of endothelial cells, often disclosing primitive clefts without hematopoietic cells inside, and neither pericytes nor basal lamina surrounded the endothelial cells at any gestational age studied. This suggests that pericytes recruitment around villous stromal vessels is defective in CHMs and links to the persistent vascular immaturity of the villous stroma in CHMs, which in turns leads to hydropic villi.

  11. Pigmentary Markers in Danes - Associations with Quantitative Skin Colour, Nevi Count, Familial Atypical Multiple-Mole, and Melanoma Syndrome.

    Directory of Open Access Journals (Sweden)

    Peter Johansen

    Full Text Available To investigate whether pigmentation genes involved in the melanogenic pathway (melanogenesis contributed to melanoma predisposition, we compared pigmentary genetics with quantitative skin pigmentation measurements, the number of atypical nevi, the total nevus count, and the familial atypical multiple mole and melanoma (FAMMM syndrome. We typed 32 pigmentary SNP markers and sequenced MC1R in 246 healthy individuals and 116 individuals attending periodic control for malignant melanoma development, 50 of which were diagnosed with FAMMM. It was observed that individuals with any two grouped MC1R variants (missense, NM_002386:c. 456C > A (p.TYR152*, or NM_002386:c.83_84insA (p.Asn29Glnfs*14 had significantly (p<0.001 lighter skin pigmentation of the upper-inner arm than those with none or one MC1R variant. We did not observe any significant association of the MC1R variants with constitutive pigmentation measured on the buttock area. We hypothesize that the effect of MC1R variants on arm pigmentation is primarily reflecting the inability to tan when subjected to UVR. A gender specific effect on skin pigmentation was also observed, and it was found that the skin pigmentation of females on average were darker than that of males (p<0.01. We conclude that MC1R variants are associated with quantitative skin colour in a lightly pigmented Danish population. We did not observe any association between any pigmentary marker and the FAMMM syndrome. We suggest that the genetics of FAMMM is not related to the genetics of the pigmentary pathway.

  12. Comparison of nitrous oxide (N2O) analyzers for high-precision measurements of atmospheric mole fractions

    Science.gov (United States)

    Lebegue, B.; Schmidt, M.; Ramonet, M.; Wastine, B.; Yver Kwok, C.; Laurent, O.; Belviso, S.; Guemri, A.; Philippon, C.; Smith, J.; Conil, S.; Jost, H. J.; Crosson, E. R.

    2015-10-01

    Over the last few decades, in-situ measurements of atmospheric N2O mole fractions have been performed using gas chromatographs (GCs) equipped with electron capture detectors (ECDs). When trying to meet the World Meteorological Organization's (WMO) quality goal, this technique becomes very challenging as the detectors are highly non-linear and the GCs at remote stations require a considerable amount of maintenance by qualified technicians to maintain good short-term and long-term repeatability. With more robust optical spectrometers being now available for N2O measurements, we aim to identify a robust and stable analyzer that can be integrated into atmospheric monitoring networks, such as the Integrated Carbon Observation System (ICOS). In this study, we tested seven analyzers that were developed and commercialized from five different companies and compared the results with established techniques. Each instrument was characterized during a time period of approximately eight weeks. The test protocols included the characterization of the short-term and long-term repeatability, drift, temperature dependence, linearity and sensitivity to water vapor. During the test period, ambient air measurements were compared under field conditions at the Gif-sur-Yvette station. All of the analyzers showed a standard deviation better than 0.1 ppb for the 10 min averages. Some analyzers would benefit from improvements in temperature stability to reduce the instrument drift, which could then help in reducing the frequency of calibrations. For most instruments, the water vapor correction algorithms applied by companies are not sufficient for high-precision atmospheric measurements, which results in the need to dry the ambient air prior to analysis.

  13. Effects of the InAIN growth temperature and In mole fraction on subband transport in InxAI1-xN/(AIN)/GaN/AIN heterostructures

    International Nuclear Information System (INIS)

    Subband transport properties of the two-dimensional electron gas in InxAI1-xN/(AIN)/GaN/AIN heterostructures were investigated by means of variable magnetic-field Hall measurement between 30 K and 290 K. The experimental data was analyzed by using quantitative mobility spectrum analysis technique. The 2-dimensional electron gas with 1 or 2 subbands and the 2-dimensional hole were detected with i-quantitative mobility spectrum analysis technique. Mobility of the second subband of 2DEG was found to be higher than that of the first subband. The sheet carrier density for Hall, the first and the second subband were reduced while Indium mole fraction was increasing. This behavior is a result of total bound interface sheet density. During In mole fraction was increasing, second subband mobility was decreased.The first subband and Hall mobility was decreased once InAIN growth temperature was increased

  14. A low-fluorine solution with a 2:1 F/Ba mole ratio for the fabrication of YBCO films

    DEFF Research Database (Denmark)

    Wu, Wei; Feng, Feng; Yue, Zhao;

    2014-01-01

    In previously reported low-fluorine MOD-YBCO studies, the lowest F/Ba mole ratio of the precursor solution was 4.5. Further lowering the F/Ba ratio would bring benefits for the environment, thick film deposition, and an understanding of the heat treatment process. On the other hand, the F/Ba ratio...... must be at least 2 for full conversion of the Ba-precursor to BaF2 to avoid the formation of BaCO3, which is detrimental to the superconducting performance of YBCO films. In this study, a solution with a 2:1 F/Ba mole ratio was developed, and the fluorine content of this solution was approximately only...

  15. Tunable diode laser absorption spectroscopy-based tomography system for on-line monitoring of two-dimensional distributions of temperature and H2O mole fraction

    Science.gov (United States)

    Xu, Lijun; Liu, Chang; Jing, Wenyang; Cao, Zhang; Xue, Xin; Lin, Yuzhen

    2016-01-01

    To monitor two-dimensional (2D) distributions of temperature and H2O mole fraction, an on-line tomography system based on tunable diode laser absorption spectroscopy (TDLAS) was developed. To the best of the authors' knowledge, this is the first report on a multi-view TDLAS-based system for simultaneous tomographic visualization of temperature and H2O mole fraction in real time. The system consists of two distributed feedback (DFB) laser diodes, a tomographic sensor, electronic circuits, and a computer. The central frequencies of the two DFB laser diodes are at 7444.36 cm-1 (1343.3 nm) and 7185.6 cm-1 (1391.67 nm), respectively. The tomographic sensor is used to generate fan-beam illumination from five views and to produce 60 ray measurements. The electronic circuits not only provide stable temperature and precise current controlling signals for the laser diodes but also can accurately sample the transmitted laser intensities and extract integrated absorbances in real time. Finally, the integrated absorbances are transferred to the computer, in which the 2D distributions of temperature and H2O mole fraction are reconstructed by using a modified Landweber algorithm. In the experiments, the TDLAS-based tomography system was validated by using asymmetric premixed flames with fixed and time-varying equivalent ratios, respectively. The results demonstrate that the system is able to reconstruct the profiles of the 2D distributions of temperature and H2O mole fraction of the flame and effectively capture the dynamics of the combustion process, which exhibits good potential for flame monitoring and on-line combustion diagnosis.

  16. Low sulfide levels and a high degree of cystathionine β-synthase (CBS) activation by S-adenosylmethionine (SAM) in the long-lived naked mole-rat

    OpenAIRE

    Maja Dziegelewska; Susanne Holtze; Christiane Vole; Ulrich Wachter; Uwe Menzel; Michaela Morhart; Marco Groth; Karol Szafranski; Arne Sahm; Christoph Sponholz; Philip Dammann; Klaus Huse; Thomas Hildebrandt; Matthias Platzer

    2016-01-01

    Hydrogen sulfide (H2S) is a gaseous signalling molecule involved in many physiological and pathological processes. There is increasing evidence that H2S is implicated in aging and lifespan control in the diet-induced longevity models. However, blood sulfide concentration of naturally long-lived species is not known. Here we measured blood sulfide in the long-lived naked mole-rat and five other mammalian species considerably differing in lifespan and found a negative correlation between blood ...

  17. Design and Implementation of Whac-a-mole Game Basd on PLD%基于PLD的打地鼠游戏的设计与实现

    Institute of Scientific and Technical Information of China (English)

    李倩

    2015-01-01

    Whack-a-mole game is a practical small game, entertainment is very strong, and can exercise the children's reaction speed, now on the market also appeared a lot of children's toys about whack-a-mole. This paper realized the basic function of the game of whack-a-mole, tells the story of the game design process, through the detailed design process for a beginner to understand the system design process based on PLD.%打地鼠游戏是一款实用性小游戏,娱乐性很强,且能够锻炼孩子们的反应速度,现在市面上也出现了很多关于打地鼠的儿童玩具。本文实现了的打地鼠游戏的基本功能,讲述了此游戏的设计实现过程,通过整个详细的设计过程让学习者了解到基于PLD的系统设计流程。

  18. Effect of SiO2/Na2O mole ratio on the properties of foam geopolymers fabricated from circulating fluidized bed fly ash

    Institute of Scientific and Technical Information of China (English)

    Ze Liu; Ning-ning Shao; Tian-yong Huang; Jun-feng Qin; Dong-min Wang; Yu Yang

    2014-01-01

    Geopolymers are three-dimensional aluminosilicates formed in a short time at low temperature by geopolymerization. In this pa-per, alkali-activated foam geopolymers were fabricated from circulating fluidized bed fly ash (CFA), and the effect of SiO2/Na2O mole ratio (0.91-1.68) on their properties was studied. Geopolymerization products were characterized by mechanical testing, scanning electron mi-croscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), and X-ray diffraction (XRD). The results show that SiO2/Na2O mole ratio plays an important role in the mechanical and morphological characteristics of geopolymers. Foam samples prepared in 28 d with a SiO2/Na2O mole ratio of 1.42 exhibit the greatest compressive strength of 2.52 MPa. Morphological analysis reveals that these foam geo-polymers appear the relatively optimized pore structure and distribution, which are beneficial to the structure stability. Moreover, a combina-tion of the Si/Al atomic ratio ranging between 1.47 and 1.94 with the Na/Al atomic ratio of about 1 produces the samples with high strength.

  19. Phase diagram of R-Fe-Co pseudoternary system with R≤33.3 %(mole fraction, R=Sm0.5Dy0.5)

    Institute of Scientific and Technical Information of China (English)

    王博文; 刘炜丽; 封文江; 金光; 郝延明; 李养贤

    2002-01-01

    Phase equilibria of the R-Fe-Co pseudoternary system with R≤33.3%(mole fraction, R=Sm0.5Dy0.5) were determined in an isothermal section at 1073K and a vertical section of RFe2-RCo2 by using OM, X-ray diffractometer, EPMA DTA techniques. There are seven intermetallic phases: (Sm, Dy)(Fe, Co)2, (Sm, Dy)(Fe, Co)3, (Sm, Dy)6(Fe, Co)23, (Sm, Dy)2(Fe, Co)7, (Sm, Dy)(Fe, Co)5, Th2Ni17-type and Th2Zn17-type (Sm, Dy)2(Fe, Co)17. The (Sm, Dy)6(Fe, Co)23 phase dissolves 36% Co(mole fraction) at 1073K. However, the (Sm, Dy)2(Fe, Co)7 phase in R2(Fe1-xCox)7 alloys dissolves about 19% Fe(mole fraction) at 1073K.

  20. Resposta ao estresse: II. Resiliência e vulnerabilidade

    Directory of Open Access Journals (Sweden)

    Nicole Leite Galvão-Coelho

    2015-06-01

    Full Text Available ResumoA crescente exposição a estressores na vida cotidiana aumentou significativamente a investigação da resposta ao estresse nas duas últimas décadas. Embora associada a consequências negativas, pois muitas patologias físicas e mentais são desencadeadas por exposição crônica a estressores, esta resposta é indispensável para sobrevivencia do indivíduo e é extremamente adaptativa quando ativada de forma aguda. Na parte I desta revisão foram abordados os conceitos de homestase e alostase e os sistemas fisiológicos ativados durante a resposta ao estresse. Na parte II serão discutidos fatores que modulam a resposta ao estresse tais como sexo, temperamento, períodos críticos do desenvolvimento e a presença ou ausência de suporte social. A interação entre os fatores genéticos e ambientais gera os perfis da resposta psicofisiológica que caracterizam os fenótipos de susceptibilidade e resiliência frente aos estressores e sua relação com uma patologia mental cada vez mais presente na sociedade moderna, o transtorno de estresse pós-traumático.

  1. Adesão ao tratamento da ambliopia

    Directory of Open Access Journals (Sweden)

    Arakaki Mara Regina

    2004-01-01

    Full Text Available OBJETIVO: Avaliar a influência da adesão no resultado do tratamento da ambliopia. MÉTODOS: Foi feito estudo retrospectivo avaliando a resposta ao tratamento da ambliopia em 151 crianças portadoras de ambliopia, tratadas com esquema de oclusão diária, com o número de dias variando de acordo com a idade da criança. Os pacientes foram separados em dois grupos que diferiam entre si pela adesão ou não ao tratamento. RESULTADOS: Observou-se que o tratamento teve melhores resultados nas crianças de 4 a 7 anos e que aderiram ao tratamento; as crianças que aderiram ao tratamento necessitaram de tempo menor de permanência em tratamento. Mesmo crianças com idade superior a 7 anos tiveram resultados positivos com a oclusão. CONCLUSÃO:O tratamento oclusivo é um meio terapêutico eficiente desde que haja a cooperação do paciente.

  2. On some Polychaetous Annelids from Curaçao

    NARCIS (Netherlands)

    Horst, R.

    1922-01-01

    Though we know already a rather large number of Polychaetous Annelids from the Caribbean Sea, hitherto, as far as I know, no Annelids have been described from the coast of the island Curaçao and I therefore was very glad, that my colleague Dr. VAN DER HORST kindly placed in my hands for identificati

  3. Spatial and Temporal Variability of Methane Mole Fractions and Exchanges in and Between Soil, Snow, and the Atmosphere in a Tundra System in Northern Alaska

    Science.gov (United States)

    Agnan, Y.; Obrist, D.; Edwards, G. C.; Moore, C.; Hedge, C.; Helmig, D.; Paxton, D.; Jacques, H.

    2015-12-01

    An important global source of atmospheric methane (CH4) is production in tundra soils (an important global source). To place constraints on the potential role that tundra soils play in global CH4 cycling, we have been continuously measuring mole the air space in soils, snow, and the atmosphere as gradient-based surface-atmosphere fluxes for arctic tundra at Toolik Field Station (68° 38' N) starting in October 2014. We have found that atmospheric CH4 mole fractions were, on average, relatively constant during the first 9 months of sampling (averaging 1.93 µmol mol-1), with pronounced diel patterns starting in May and nighttime exceeding daytime mole fractions. However, gradients measured within the soil profile showed high variability in air withdrawn from different locations of these tundra soils (Typic Aquiturbels), with one soil profile indicating a CH4 sink during fall until January; mole fractions were similar to the atmospheric measurements during winter indicating no source or sink (average 1.89 µmol mol-1). A second soil profile 5 m away showed production of CH4 (average 2.48 µmol mol-1, two-times higher than atmospheric levels), even during mid-winter when soil temperatures were below -10 °C. Measurements of CH4 in interstitial snowpack air also exhibited a similar combination of sources and sinks. We used micrometeorological gradient surface flux measurements to confirm that the area was a net source of CH4 in fall, winter, and spring, with emissions averaging 26.6, 25.2, and 16.8 mg m-2 d-1, respectively. In the summer months, we saw strong diel flux patterns with deposition during day and emission at night, corresponding with observed diel variability in CH4 snowpack mole fractions. Our results indicated a high variability of tundra landscape CH4 fluxes, which locally shift from sources to sinks with high temporal variability. CH4 oxidation by methanotrophic bacteria probably occurs in tundra soils, confirming observations in one soil, snowpack, and

  4. Insights Into the Recent Rise in Atmospheric Methane Inferred from Observed Mole Fractions and Stable Carbon Isotopes

    Science.gov (United States)

    White, J. W. C.; Michel, S. E.; Tans, P. P.; Vaughn, B. H.; Dlugokencky, E. J.; Sherwood, O.; Miller, J. B.; Masarie, K. A.

    2015-12-01

    Methane is a troublesome greenhouse gas. It has multiple natural and anthropogenic sources, including microbial production in low oxygen environments, fossil sources related to coal and natural gas production, and biomass burning, making source attribution difficult. Atmospheric methane concentration rose rapidly in the industrial period, increasing by 250%, only to stall out in the first decade this century, and then rising again after 2007. Its emission is strongly related to variables that are hard to predict, such as precipitation rates, biomass burning, and natural gas use, so future projections remain murky. And unlike CO2, which is strongly tied to energy use, anthropogenic impacts on methane are strongly tied to food production. Finally, methane is expected to be released from a thawing Arctic in large, but largely unknown quantities. Understanding methane as a greenhouse gas is imperative if anthropogenic impacts on the climate system are to be managed in the future. This talk addresses what we can say about the recent rise in methane using mole fractions and 13C data from the existing NOAA Cooperative Global Air Sampling Network. The approach is strongly data based, and while we will present model results, the data itself are clear on several points. While attention is increasingly focused on the Arctic, the north-south gradient of CH4 concentration does not support significant changes to Boreal and Arctic emissions. This finding raises the question of how methane will behave in a warmer, wetter world. We use a simple, three end-member model, run in both forward and inverse modes, to look more deeply into the sources of the recent increase. Evidence exists for recent increases in fossil sources, in line with methane production as a fuel source, although the contribution is small. Better data are needed to constrain the 13C of sources, including the fossil sources, a problem we are working on. Importantly, while the current monitoring network is adequate

  5. [Richard C. M. Mole: The Baltic states from the Soviet Union to the European Union. Identity, discourse and power in the post-communist transition of Estonia, Latvia and Lithuania] / Karsten Brüggemann

    Index Scriptorium Estoniae

    Brüggemann, Karsten, 1965-

    2014-01-01

    Arvustus: Mole, Richard C. M. The Baltic States from the Soviet Union to the European Union : identity, discourse and power in the post-communist transition of Estonia, Latvia and Lithuania. London ; New York : Routledge, 2012, 2013

  6. Frequência de mola hidatiforme em tecidos obtidos por curetagem uterina Frequency of hydatidiform mole in tissue obtained by curettage

    Directory of Open Access Journals (Sweden)

    Andressa Biscaro

    2012-06-01

    Full Text Available OBJETIVO: Determinar a frequência de mola hidatiforme em tecidos obtidos por curetagem uterina. MÉTODOS: Estudo transversal, prospectivo e descritivo que incluiu pacientes submetidas à curetagem uterina por diagnóstico de aborto ou mola hidatiforme cujo material obtido foi encaminhado para exame anatomopatológico. Foram excluídas aquelas que não aceitaram participar da pesquisa, recusando-se a assinar o Termo de Consentimento Informado Livre e Esclarecido. Foram analisadas as seguintes variáveis: achados anatomopatológicos, idade, raça/cor, número de gestações e abortos prévios, idade gestacional no momento do diagnóstico, níveis séricos quantitativos da fração beta da gonadotrofina coriônica humana e achados ultrassonográficos. As variáveis foram empregadas para a verificação com o diagnóstico histológico, considerado o padrão-ouro. Os dados foram armazenados e analisados no software Microsoft Excel® e no programa Epi-Info, versão 6.0 (STATCALC e os resultados apresentados como frequência (porcentagem ou média±desvio padrão. Para a associação entre variáveis qualitativas foi usado o teste do χ², e admitiu-se significância estatística quando pPURPOSE: To determine the frequency of hydatiform mole in tissues obtained by curettage. METHODS: A cross-sectional, prospective and descriptive conducted on patients who underwent curretage due to a diagnosis of abortion or hydatiform mole whose material was sent for pathological examination. We excluded women who did not accept to participate and refused to sign the free informed consent form. We studied the following variables: pathological findings, age, race, number of pregnancies and previous abortions, gestational age at diagnosis, quantitative serum beta fraction of human chorionic gonadotropin and ultrasound findings. The data were compared to the to histological diagnosis, considered to be the gold standard. Data were stored and analyzed in Microsoft Excel

  7. Sobre a viagem de Enrico Fermi ao Brasil em 1934

    CERN Document Server

    Caruso, Francisco

    2014-01-01

    Enrico Fermi was one of the greater physicists of the XX century. In 1934, he gave several lectures in Brazil. Invited by Theodoro Ramos to work in S\\~ao Paulo, he preferred to stay in Rome and went to the USA in 1938. However, Fermi recommended Gleb Wataghin to come in his place. Wataghin made history in Brazil, becoming one of the first Professors of the future S\\~ao Paulo University. Besides his relevance to the History of Science, Fermi eventually leaved an indelible mark on the creation and institutionalization of national scientific research due to the indication of Wataghin. Despite this fact, very little is known about Fermi's trip to Brazil. This work tries to reconstruct the fullest possible steps of the famous Italian physicist in our lands.

  8. High-Resolution Imaging of Asteroids/Satellites with AO

    Science.gov (United States)

    Merline, William

    2012-02-01

    We propose to make high-resolution observations of asteroids using AO, to measure size, shape, and pole position (spin vectors), and/or to search for satellites. We have demonstrated that AO imaging allows determination of the pole/dimensions in 1 or 2 nights on a single target, rather than the years of observations with lightcurve inversion techniques that only yield poles and axial ratios, not true dimensions. Our new technique (KOALA) combines AO imaging with lightcurve and occultation data for optimum size/shape determinations. We request that LGS be available for faint targets, but using NGS AO, we will measure several large and intermediate asteroids that are favorably placed in spring/summer of 2012 for size/shape/pole. Accurately determining the volume from the often-irregular shape allows us to derive densities to much greater precision in cases where the mass is known, e.g., from the presence of a satellite. We will search several d! ozen asteroids for the presence of satellites, particularly in under-studied populations, particularly NEOs (we have recently achieved the first-ever optical image of an NEO binary [Merline et al. 2008b, IAUC 8977]). Satellites provide a real-life lab for testing collisional models. We will search for satellites around special objects at the request of lightcurve observers, and we will make a search for debris in the vicinity of Pluto, in support of the New Horizons mission. Our shape/size work requires observations over most of a full rotation period (typically several hours).

  9. Cuidado ao idoso deprimido e institucionalizado à luz da Complexidade

    Directory of Open Access Journals (Sweden)

    Cenir Gonçalves Tier

    2008-06-01

    Full Text Available Instituições de Longa Permanência para Idosos (ILPI são estabelecimentos para atendimento integral, institucionalizando pessoas de 60 anos e mais, dependentes/ou não, que não dispõem de condições para permanecer com a família ou/em seu domicílio. A institucionalização pode desencadear doenças, dentre elas a depressão. Foi objetivo deste artigo de atualização fazer uma reflexão sobre a relação do cuidado ao idoso deprimido e residente em ILPI com três princípios da Complexidade segundo Edgar Morin. Primeiro, se reflete sobre a complexidade; depois, se relaciona o cuidado ao idoso deprimido e residente em ILPI, com os princípios dialógico, recursivo e hologramático. Percebeu-se que a Complexidade pode sustentar teoricamente, não só a compreensão do fenômeno depressão no idoso residente em uma ILPI, como também inspirar o modo de cuidar que direcione aos trabalhadores da saúde, que atuam junto à pessoa idosa, a abordarem o idoso de forma mais global. Para tanto deve ser utilizada a Avaliação Multidimensional do Idoso, que analisa as várias dimensões da pessoa idosa, contribuindo no desenvolvimento de um plano de cuidado/tratamento e acompanhamento multidisciplinar e interdisciplinar adequados. A Complexidade vem sendo utilizada, por enfermeiros, para entender melhor a enfermagem e prestar cuidado mais adequado ao ser humano.

  10. LDEF results for polymer-matrix composite experiment AO 180

    International Nuclear Information System (INIS)

    This report represents a summary of the results obtained to-date on a polymer matrix composite experiment (AO 180) located at station D-12, about 82 deg off the 'ram' direction. Different material systems comprised of graphite, boron, and aramid (Kevlar) fiber reinforcements were studied. Although previous results were presented on in-situ thermal-vacuum cycling effects, particularly dimensional changes associated with outgassing, additional comparative data will be shown from ground-based tests on control and flight samples. The system employed was fully automated for thermal-vacuum cycling using a laser interferometer for monitoring displacements. Erosion of all three classes of materials due to atomic oxygen (AO) will also be discussed, including angle of incidence effects. Data from this experiment will be compared to published results for similar materials in other LDEF experiments. Composite materials' erosion yields will be presented on an AO design nomogram useful for estimating total material loss for given exposure conditions in low Earth orbit (LEO). Optical properties of these materials will also be compared with control samples. A survey of the damage caused by micrometeoroids/debris impacts will be addressed as they relate to polymer matrix composites. Correlations between hole size and damage pattern will be given. Reference to a new nomogram for estimating the number distribution of micrometeoroid/debris impacts for a given space structure as a function of time in LEO will be addressed based on LDEF data

  11. Simulations of (MC)AO for a 100-m telescope

    Science.gov (United States)

    Le Louarn, Miska; Verinaud, Christophe; Yaitskova, Natalia; Korkiakoski, Visa; Fedrigo, Enrico; Hubin, Norbert N.

    2004-10-01

    In this paper, we summarize the analysis made on various Adaptive Optics (AO) modes (including Shack-Hartmann (SH) and Pyramid Wavefront Sensors (PWS)) for the OverWhelmingly Large telescope (OWL). We will show some early results of the performance to be expected with a first generation AO system, working in the infrared. Several telescope diameters were considered to see the variations as a function of telescope diameter. This is also compatible with the concept of "grow a telescope" where the telescope diameter of OWL grows from 60m to 100m as a function of time. In a first phase, to simplify the problem, the effects of the central obstruction were neglected. However, for the Shack-Hartmann (SH) simulations, additional simulations were carried out with a simulated OWL pupil, including segmentation errors. We show some early results for a ground-layer correction system, working with three natural guide stars (NGSs) and a single deformable mirror (DM). An MCAO system based on 2 DMs, 3 NGSs is also investigated. For the last two systems, our results are found to be in very good agreement with Cibola, an analytical AO modeling tool. We show that some outer scale of turbulence effects improve slightly the correction quality when going from a telescope diameter of 10m to 100m.

  12. Resposta ao estresse: I. Homeostase e teoria da alostase

    Directory of Open Access Journals (Sweden)

    Maria Bernardete Cordeiro de Sousa

    2015-03-01

    Full Text Available ResumoOs seres vivos desenvolvem ao longo de sua história evolutiva mecanismos de enfrentamento às condições adversas originadas tanto no ambiente geofísico como no ambiente social. Esta resposta adaptativa é coordenada e envolve diferentes sistemas funcionais, particularmente, os sistemas nervoso, endócrino e imune, e é denominada de resposta ao estresse e deve atender a duas demandas principais da vida: sobrevivência e reprodução. Esta revisão tem o objetivo de discutir o emprego do conceito clássico de homeostase e um conceito alternativo, alostase, que inclui os mecanismos preditivos e reativos de regulação, assim como os diferentes níveis de impacto dos estressores crônicos, resultando em sobrecarga alostática que pode ou não se seguir de falha alostática. Os mecanismos neurais, hormonais, imunes, sistêmicos e moleculares, que compreendem os sistemas alóstaticos subjacentes à resposta ao estresse são também apresentados.

  13. Three years of greenhouse gas column-averaged dry air mole fractions retrieved from satellite – Part 1: Carbon dioxide

    Directory of Open Access Journals (Sweden)

    R. Macatangay

    2008-03-01

    Full Text Available Carbon dioxide (CO2 and methane (CH4 are the two most important anthropogenic greenhouse gases. SCIAMACHY on ENVISAT is the first satellite instrument whose measurements are sensitive to concentration changes of the two gases at all altitude levels down to the Earth's surface where the source/sink signals are largest. We have processed three years (2003–2005 of SCIAMACHY near-infrared nadir measurements to simultaneously retrieve vertical columns of CO2 (from the 1.58 μm absorption band, CH4 (1.66 μm and oxygen (O2 A-band at 0.76 μm using the scientific retrieval algorithm WFM-DOAS. We show that the latest version of WFM-DOAS, version 1.0, which is used for this study, has been significantly improved with respect to its accuracy compared to the previous versions while essentially maintaining its high processing speed (~1 minute per orbit, corresponding to ~6000 single measurements, and per gas on a standard PC. The greenhouse gas columns are converted to dry air column-averaged mole fractions, denoted XCO2 (in ppm and XCH4 (in ppb, by dividing the greenhouse gas columns by simultaneously retrieved dry air columns. For XCO2 dry air columns are obtained from the retrieved O2 columns. For XCH4 dry air columns are obtained from the retrieved CO2 columns because of better cancellation of light path related errors compared to using O2 columns retrieved from the spectrally distant O2 A-band. Here we focus on a discussion of the XCO2 data set. The XCH4 data set is discussed in a separate paper (Part 2. In order to assess the quality of the retrieved XCO2 we present comparisons with Fourier Transform Spectroscopy (FTS XCO2 measurements at two northern hemispheric mid-latitude ground stations. To assess the quality globally, we present detailed comparisons with global XCO2 fields obtained from NOAA's CO2 assimilation system CarbonTracker. For the Northern Hemisphere we find good agreement with the reference data for the CO2 seasonal cycle and the CO2

  14. Three years of greenhouse gas column-averaged dry air mole fractions retrieved from satellite – Part 2: Methane

    Directory of Open Access Journals (Sweden)

    W. Peters

    2008-05-01

    Full Text Available Carbon dioxide (CO2 and methane (CH4 are the two most important anthropogenic greenhouse gases. SCIAMACHY on ENVISAT is the first satellite instrument whose measurements are sensitive to concentration changes of the two gases at all altitude levels down to the Earth's surface where the source/sink signals are largest. We have processed three years (2003–2005 of SCIAMACHY near-infrared nadir measurements to simultaneously retrieve vertical columns of CO2 (from the 1.58 μm absorption band, CH4 (1.66 μm and oxygen (O2 A-band at 0.76 μm using the scientific retrieval algorithm WFM-DOAS. We show that the latest version of WFM-DOAS, version 1.0, which is used for this study, has been significantly improved with respect to its accuracy compared to the previous versions while essentially maintaining its high processing speed (~1 min per orbit, corresponding to ~6000 single measurements, and per gas on a standard PC. The greenhouse gas columns are converted to dry air column-averaged mole fractions, denoted XCO2 (in ppm and XCH4 (in ppb, by dividing the greenhouse gas columns by simultaneously retrieved dry air columns. For XCO2 dry air columns are obtained from the retrieved O2 columns. For XCH4 dry air columns are obtained from the retrieved CO2 columns because of better cancellation of light path related errors compared to using O2 columns retrieved from the spectrally distant O2 A-band. Here we focus on a discussion of the XCH4 data set. The XCO2 data set is discussed in a separate paper (Part 1. For 2003 we present detailed comparisons with the TM5 model which has been optimally matched to highly accurate but sparse methane surface observations. After accounting for a systematic low bias of ~2% agreement with TM5 is typically within 1–2%. We investigated to what extent the SCIAMACHY XCH4 is influenced by the variability of atmospheric CO2 using global CO2 fields from NOAA's CO2 assimilation system CarbonTracker. We show that the CO2 corrected

  15. Fatores associados a baixa adesao ao tratamento medicamentoso em idosos

    Directory of Open Access Journals (Sweden)

    Noemia Urruth Leao Tavares

    2013-12-01

    Full Text Available OBJETIVO : Analisar fatores associados à baixa adesão ao tratamento medicamentoso em idosos. MÉTODOS : Estudo transversal de base populacional, com amostra representativa de 1.593 indivíduos com 60 anos ou mais, residentes na região urbana de Bagé, RS, em 2008. A amostragem foi realizada em múltiplos estágios. Os dados foram coletados em entrevistas individuais nos domicílios. Analisou-se a associação entre a baixa adesão referida ao tratamento medicamentoso mensurado pelo Brief Medication Questionnaire (BMQ e fatores demográficos, socioeconômicos, comportamentais e de saúde, assistência e prescrição. Foi utilizado modelo de regressão de Poisson para estimar as razões de prevalência bruta e ajustada, os respectivos intervalos de confiança de 95% e p-valor (teste de Wald. RESULTADOS : Cerca de 78,0% dos indivíduos referiram ter usado algum medicamento nos sete dias precedentes à entrevista. Desses, cerca de 1 / 3 foram considerados com baixa adesão ao tratamento. Os fatores significativamente associados à baixa adesão foram: idade (65 a 74 anos, não ter plano de saúde, ter que comprar (totalmente ou em parte os seus medicamentos, ter três ou mais morbidades, possuir incapacidade instrumental para a vida diária e usar três ou mais medicamentos. CONCLUSÕES : A utilização elevada de medicamentos, decorrente da alta prevalência de doenças crônico-degenerativas em idosos, e o acesso ao tratamento devem ser considerados pelos profissionais de saúde para adoção de estratégias que visem diminuir a baixa adesão ao tratamento, aumentando a resolutividade terapêutica e a qualidade de vida desses pacientes.

  16. Absence of Maternal Methylation in Biparental Hydatidiform Moles from Women with NLRP7 Maternal-Effect Mutations Reveals Widespread Placenta-Specific Imprinting

    Science.gov (United States)

    Sanchez-Delgado, Marta; Martin-Trujillo, Alejandro; Tayama, Chiharu; Vidal, Enrique; Esteller, Manel; Iglesias-Platas, Isabel; Deo, Nandita; Barney, Olivia; Maclean, Ken; Hata, Kenichiro; Nakabayashi, Kazuhiko; Fisher, Rosemary; Monk, David

    2015-01-01

    Familial recurrent hydatidiform mole (RHM) is a maternal-effect autosomal recessive disorder usually associated with mutations of the NLRP7 gene. It is characterized by HM with excessive trophoblastic proliferation, which mimics the appearance of androgenetic molar conceptuses despite their diploid biparental constitution. It has been proposed that the phenotypes of both types of mole are associated with aberrant genomic imprinting. However no systematic analyses for imprinting defects have been reported. Here, we present the genome-wide methylation profiles of both spontaneous androgenetic and biparental NLRP7 defective molar tissues. We observe total paternalization of all ubiquitous and placenta-specific differentially methylated regions (DMRs) in four androgenetic moles; namely gain of methylation at paternally methylated loci and absence of methylation at maternally methylated regions. The methylation defects observed in five RHM biopsies from NLRP7 defective patients are restricted to lack-of-methylation at maternal DMRs. Surprisingly RHMs from two sisters with the same missense mutations, as well as consecutive RHMs from one affected female show subtle allelic methylation differences, suggesting inter-RHM variation. These epigenotypes are consistent with NLRP7 being a maternal-effect gene and involved in imprint acquisition in the oocyte. In addition, bioinformatic screening of the resulting methylation datasets identified over sixty loci with methylation profiles consistent with imprinting in the placenta, of which we confirm 22 as novel maternally methylated loci. These observations strongly suggest that the molar phenotypes are due to defective placenta-specific imprinting and over-expression of paternally expressed transcripts, highlighting that maternal-effect mutations of NLRP7 are associated with the most severe form of multi-locus imprinting defects in humans. PMID:26544189

  17. Echinococcus multilocularis in Kyrgyzstan: similarity in the Asian EmsB genotypic profiles from village populations of Eastern mole voles (Ellobius tancrei) and dogs in the Alay valley.

    Science.gov (United States)

    Afonso, E; Knapp, J; Tête, N; Umhang, G; Rieffel, D; van Kesteren, F; Ziadinov, I; Craig, P S; Torgerson, P R; Giraudoux, P

    2015-11-01

    Echinococcus multilocularis is a cestode that causes human alveolar echinococcosis, a lethal zoonosis of public health concern in central Asia and western China. In the present study, one of 42 Eastern mole voles (Ellobius tancrei) caught in Sary Mogol (Alay valley, southern Kyrgyzstan) presented liver lesions with E. multilocularis from which the EmsB target was amplified. The Asian profile obtained was almost identical to one amplified from domestic dog faeces collected in a nearby village. This observation adds additional information to the potential role of E. tancrei in the transmission of E. multilocularis, and to the known distribution range of E. multilocularis (Asian strain) in central Asia. PMID:26137938

  18. Suporte relacionado ao cuidado em saúde ao doente com aids: o modelo de comboio e a enfermagem

    Directory of Open Access Journals (Sweden)

    Edilene Aparecida Araújo da Silveira

    2011-06-01

    Full Text Available O presente estudo teve como objetivo conhecer a relação e a troca de suporte entre o doente com AIDS e pessoas à sua volta. O estudo está baseado no modelo de comboio das relações sociais que tem como uma de suas características a representação da rede em três círculos concêntricos. Os participantes eram pessoas que estavam internadas e que falaram sobre o suporte relacionado ao cuidado em saúde proporcionado por pessoas próximas, ou seja, que pertenciam ao círculo interno do comboio. A maioria dos participantes descreveu o círculo como sendo composto por no máximo cinco integrantes, sendo que pessoas da família foram as mais citadas. Os profissionais de saúde precisam conhecer o paciente e seu comboio, reconhecendo-os no contexto psicossocial e cultural de forma a favorecer a aceitação da soropositividade, mudanças no estilo de vida, ajuda nos cuidados de saúde e adesão ao tratamento.

  19. DESCRIÇÃO ANATÔMICA DO LENHO DE Melaleuca leucadendron (L. L

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    Linéia Roberta Zen

    2016-03-01

    Full Text Available This work aimed the anatomical description of Melaleuca leucadendron wooden. The study was conducted from an individual tree collecting three discs for confection of histological slides and macerated. Was used to mashing nitricacetic method and for histology was used simple staining with 1% safranin. The wood anatomy agrees in general aspects to the typical pattern of Myrtaceae Family: flocking diffuse porosity, solitary pores, simple perforation plates, besides paratracheal axial parenchyma linear aliforme, very numerous rays and heterocellular, pits-ray vascular parenchyma-vascular and fibrous tissue composed of prominent fibrotraqueoids, very short fibers, distinct growth rings of walls marked by the end of the fibers flattened latewood. Qualitatively and quantitatively the wood did not reveal expressive characteristic, thus can be characterized by presenting a relatively simple anatomical structure, agreeing in general lines to Myrtaceae family.

  20. Oficina de trabalho: "mulher-uma viagem ao seu corpo"

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    Maria Helena Costa Amorim

    1996-06-01

    Full Text Available Nas mulheres brasileiras, a morbidade por câncer de colo uterino e de mama é alta, mesmo que estas patologias sejam preveníveis e diagnosticadas precocemente. A cobertura dos serviços de saúde nesta área é inadequada, considerando-se a tecnologia simples e barata a ser utilizada na prevenção e detecção precoce destes tipos de câncer. Observamos que poucas são as atividades desenvolvidas com o objetivo de educar a mulher quanto ao auto conhecimento do corpo. Dessa forma, em 1993, elaboramos uma Oficina de Trabalho intitulada: " Mulher-uma viagem ao seu corpo", composta de 6 (seis dinâmicas onde a participação de cada mulher é intensa por ser um processo envolvente. A Oficina é desenvolvida por 1 (um docente, 3 (três enfermeiras e acadêmicos de Enfermagem da Universidade Federal do Espírito Santo. São inscritas 30 (trinta participantes por Oficina, sendo que cada uma recebe crachá de participação. Esta oficina é composta de 6 (cinco dinâmicas que se desenvolvem num ambiente descontraído e aconchegante: Dinâmica 1 - História de Bolso; Dinâmica 2 - Toque das Mãos; Dinâmica 3 - Desenho/Modelagem; Dinâmica 4 - Viagem ao Corpo; Dinâmica 5 - O Auto Exame; Dinâmica 6 - Percebendo o corpo.

  1. Integrando a retórica ao game design

    OpenAIRE

    Moroni, Leonardo Mendes

    2013-01-01

    Resumo: O potencial dos jogos eletrônicos como mídia que atinge camadas cada vez mais extensas da população, com reflexos sociais, culturais e econômicos, é evidente. No entanto, jogos que alcançam grande sucesso comercial objetivam, essencialmente, propiciar diversão aos seus usuários. Com base nesta premissa, tanto usuários quanto avaliadores desta mídia acabam por desconsiderar o potencial que os jogos oferecem em termos de veicular mensagens com conteúdo relevante para a vida real, como, ...

  2. Mudança organizacional : do prescrito ao real

    OpenAIRE

    Sinval, Jorge Fernando Pereira

    2011-01-01

    As organizações dos dias de hoje enfrentam um ambiente cada vez mais dinâmico e em constante mudança. Necessitam de adaptar-se aos novos desafios. Com as crescentes evoluções tecnológicas, que ocorrem em quase todos os sectores de atividade, a maior parte dos trabalhadores é confrontada, em algum momento do seu percurso profissional, com a introdução de mudanças no seu posto de trabalho, mudanças com as quais terão de lidar. A mudança organizacional influencia quer a empresa, quer o trabalhad...

  3. Akreos Adapt AO Intraocular Lens Opacification: A Case Report

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    Matteo Forlini

    2013-09-01

    Full Text Available A 79-year-old hyperglycemic patient was referred to the ‘Santa Maria delle Croci' Hospital, Ravenna, Italy. He presented with visual impairment in the right eye. Four years ago, he had had an uneventful cataract surgery in the right eye. We observed an opacification of the intraocular lens (IOL causing significant visual disturbance. The IOL was exchanged. Unfortunately, pathologic analysis was not performed. Patient-related factors such as hyperglycemia and hypertension might have been responsible for the opacification. To our knowledge, there is only one previous report of opacification of the Akreos Adapt AO IOL.

  4. Effects of KOH:ZnCl2 mole ratio on the phase formation, morphological and inhibitive properties of potassium zinc phosphate (PZP) pigments

    International Nuclear Information System (INIS)

    Graphical abstract: This figure illustrates the inhibition mechanism. The film precipitation on the anodic and cathodic regions of the metal surface causes a drop in dissolution rate of steel. - Highlights: • We synthesized the ZP pigments via coprecipitation method. • Effect of KOH:ZnCl2 on phase formation, morphology and inhibitive performance of pigment. • KOH:ZnCl2 ratio is effective on phase formation and morphology of ZP pigments. • KZn2H(PO4)2 phase showed superior corrosion inhibition behavior than KZnPO4. - Abstract: Different types of potassium zinc phosphate (PZP) pigments were synthesized by a co-precipitation method. The PZPs were obtained through changing KOH:ZnCl2 mole ratio. The chemical composition of the pigments was studied by X-ray diffraction, Fourier transform infrared spectroscopy and scanning electron microscopy (SEM). Then, the extracts of the PZPs were prepared in 3.5% (w/w) NaCl solution. The inhibitive performance of the pigments was investigated by polarization technique and SEM surface analysis through dipping mild steel panels in the pigment extracts for different immersion times. Results showed that changing ZnCl2/KOH mole ratio could influence formation of KZn2H(PO4)2 and KZnPO4 phases. It was known that the KZn2H(PO4)2 phase has a superior corrosion inhibition behavior in 3.5% NaCl solution than KZnPO4 phase

  5. How attractive is the girl next door? An assessment of spatial mate acquisition and paternity in the solitary Cape dune mole-rat, Bathyergus suillus.

    Directory of Open Access Journals (Sweden)

    Timothy C Bray

    Full Text Available Behavioural observations of reproduction and mate choice in wild fossorial rodents are extremely limited and consequently indirect methods are typically used to infer mating strategies. We use a combination of morphological, reproductive, spatial, and genetic data to investigate the reproductive strategy of a solitary endemic species, the Cape dune mole-rat Bathyergus suillus. These data provide the first account on the population dynamics of this species. Marked sexual dimorphism was apparent with males being both significantly larger and heavier than females. Of all females sampled 36% had previously reproduced and 12% were pregnant at the time of capture. Post-partum sex ratio was found to be significantly skewed in favour of females. The paternity of fifteen litters (n = 37 was calculated, with sires assigned to progeny using both categorical and full probability methods, and including a distance function. The maximum distance between progeny and a putative sire was determined as 2149 m with males moving between sub-populations. We suggest that above-ground movement should not be ignored in the consideration of mate acquisition behaviour of subterranean mammals. Estimated levels of multiple paternity were shown to be potentially as high as 26%, as determined using sibship and sire assignment methods. Such high levels of multiple paternity have not been found in other solitary mole-rat species. The data therefore suggest polyandry with no evidence as yet for polygyny.

  6. Gestação gemelar de mola hidatiforme completa com feto vivo Twin pregnancy with complete hydatidiform mole and living fetus

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    Daniela Angerame Yela

    2011-04-01

    Full Text Available A gestação gemelar de uma mola hidatiforme completa coexistindo com um feto vivo é uma entidade rara. Os poucos casos descritos na literatura mostram que, em geral, esse tipo de gestação cursa com risco aumentado de aborto espontâneo, parto prematuro, morte fetal intraútero, sangramento, pré-eclâmpsia e doença trofoblástica persistente. Neste artigo, descreveremos o caso de uma primigesta de 20 anos de idade que apresentou uma gestação gemelar de feto vivo com mola completa, a qual transcorreu sem intercorrências e complicações e cujo diagnóstico diferencial com degeneração da placenta foi feito com anatomopatológico.Twin pregnancy with a complete hydatidiform mole and a living fetus is a rare entity. According to the few cases described in the literature, this kind of gestation commonly has higher risks of miscarriage, preterm delivery, intrauterine fetal death, bleeding, preeclampsia and persistent trophoblastic disease. This study reports the case of a 20 years old primiparous patient with complete hydatidiform mole and living fetus, whose pregnancy was successfully carried to term. The differential diagnosis with placental degeneration was reached through anatomopathological investigation.

  7. Reproduction is associated with a tissue-dependent reduction of oxidative stress in eusocial female Damaraland mole-rats (Fukomys damarensis.

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    Christina M Schmidt

    Full Text Available Oxidative stress has been implicated as both a physiological cost of reproduction and a driving force on an animal's lifespan. Since increased reproductive effort is generally linked with a reduction in survival, it has been proposed that oxidative stress may influence this relationship. Support for this hypothesis is inconsistent, but this may, in part, be due to the type of tissues that have been analyzed. In Damaraland mole-rats the sole reproducing female in the colony is also the longest lived. Therefore, if oxidative stress does impact the trade-off between reproduction and survival in general, this species may possess some form of enhanced defense. We assessed this relationship by comparing markers of oxidative damage (malondialdehyde, MDA; protein carbonyls, PC and antioxidants (total antioxidant capacity, TAC; superoxide dismutase, SOD in various tissues including plasma, erythrocytes, heart, liver, kidney and skeletal muscle between wild-caught reproductive and non-reproductive female Damaraland mole-rats. Reproductive females exhibited significantly lower levels of PC across all tissues, and lower levels of MDA in heart, kidney and liver relative to non-reproductive females. Levels of TAC and SOD did not differ significantly according to reproductive state. The reduction in oxidative damage in breeding females may be attributable to the unusual social structure of this species, as similar relationships have been observed between reproductive and non-reproductive eusocial insects.

  8. The burying behavior of the mole crabs before and after an accident with urban sewage efluents in Bombinhas Beach, Santa Catarina, Brazil

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    Ita Oliveira Silva

    2011-12-01

    Full Text Available Several environmental factors may interfere in the behavior of mole crab (Emerita brasiliensis Schmitt, 1935, such as the discharge of urban pollutants on the shore, which can be toxic. During a study of the impact of human activities on a beach in Southern Brazil, opportunistically it was tested if burying behavior of the mole crab were affected after an accident causing the discharge of urban effluents. When comparing the period before (two days and after (one day the accident, there was a substantial increase in the concentration of ammonia in the seawater, but pH, water temperature, salinity, and the microclimatic conditions remained stable. During the increased ammonia phase, we captured individuals of smaller size, but the latency in an burying test conducted in an aquarium, immediately after the capture, remained unaltered. The discharge of organic pollutants seems affected the surf zone, where small individuals were more abundant, supposedly males and juveniles but not adult females. The maintenance of burying latency by males and juveniles seems to suggest a greater physiological resistance to a short term contamination by ammonia.

  9. Effect of Mole Percentage of Crosslinker of Silver-poly(N-isopropylacrylamide-co-acrylic acid Hybrid Microgels on Catalytic Reduction of Nitrobenzene

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    Zahoor H. FAROOQI

    2015-02-01

    Full Text Available Poly(N-isopropylacrylamide-co-acrylic acid microgels [P(NIPAM-co-AAc] with 2, 4, 6 and 8 mole percentage of N,N-methylene-bis-acrylamide were used as micro-reactors for the fabrication of Ag nanoparticles using the in situ reduction method. The pure and hybrid microgels were characterized by Fourier transform infrared and Ultraviolet-Visible spectroscopies. Silver-poly(N-isopropylacrylamide-co-acrylic acid hybrid microgels [Ag-P(NIPAM-co-AAc] with different crosslinker contents were used as catalysts for reduction of nitrobenzene (NB in aqueous medium in order to investigate the effect of crosslinker content on the value of apparent rate constant (kapp. 0.041, 0.146, 0.2388 and 0.255 min-1 were found as values of kapp for catalytic reduction of NB using hybrid microgels with 2, 4, 6 and 8 mole percentage of crosslinker, respectively. The effect of crosslinker feed content of hybrid microgels on catalytic activity for reduction of NB was compared to that of reduction of p-nitrophenol in aqueous medium.

  10. Neuroanatomical investigation of the gonadotrophin-releasing hormone 1 system in the seasonally breeding Cape dune mole-rat, Bathyergus suillus.

    Science.gov (United States)

    Hart, Leanne; Bennett, Nigel C; Kalamatianos, Theodosis; Oosthuizen, Maria K; Jarvis, Jennifer U M; O'Riain, M Justin; Coen, Clive W

    2008-10-22

    The gonadotrophin-releasing hormone 1 (GnRH1) system has been investigated immunohistochemically in Cape dune mole-rats (Bathyergus suillus), subterranean rodents that normally display severe aggression towards conspecifics. These animals breed seasonally and show a reduced mean plasma level of luteinising hormone during the non-breeding season. GnRH1-immunoreactive (ir) cell bodies and processes are found in the septal/preoptic area and the mediobasal hypothalamus; the cell bodies are found in equal measure in these two regions. Dense aggregations of GnRH1-ir fibres are present in the organum vasculosum of the lamina terminalis and the external zone of the median eminence. The total number of detectable GnRH1-ir cell bodies does not differ between the sexes or within the sexes between breeding and non-breeding seasons. Similarly there is no difference in the distribution of detectable GnRH1-ir cell bodies in male and female mole-rats in and out of the breeding season. Although the average size of GnRH1-ir cell bodies does not differ between the seasons in males, their size in females is significantly smaller in the non-breeding season. Whether this reduced size reflects reduced GnRH1 synthesis remains to be determined.

  11. Alternativas de controle pós-colheita da podridão-parda e da podridão-mole em frutos de pessegueiro Alternatives for post-harvest control of brown rot and soft rot in peach fruits

    Directory of Open Access Journals (Sweden)

    Vicente Luiz de Carvalho

    2009-03-01

    Full Text Available As exigências do consumidor são cada vez maiores com relação à qualidade de produtos in natura. As podridões, além de causar perdas na produção, reduzem a qualidade final do fruto, interferindo significativamente na comercialização. Objetivou-se, com este trabalho, avaliar a eficiência de produtos alternativos, aplicados na pós-colheita, no controle da podridão-parda (Monilinia fructicola e da podridão-mole (Rhizopus spp. em pêssegos. O experimento foi conduzido no município de Nepomuceno-MG, em talhão de pessegueiro da cultivar Diamante, com 10 anos de idade. O delineamento experimental utilizado foi o inteiramente casualizado, com 7 tratamentos e 3 repetições. Para o estudo, foram selecionados frutos sem lesões e sem sintomas das doenças. Os frutos foram mergulhados por 30 segundos em solução contendo os seguintes tratamentos: 1-Óleo de cravo 0,01%; 2-Dióxido de cloro 0,1%; 3-Dióxido de cloro 0,05%; 4-Cloreto de benzalcônio 0,25%; 5-Dicloran 0,12%; 6-Iprodione 0,15% e 7-Testemunha (somente água. Após os tratamentos, os frutos, em número de 10, foram colocados em bandejas esterilizadas, em três repetições. O experimento foi conduzido em condições de ambiente não controlado, sendo feitas avaliações do desenvolvimento das doenças aos 3 e aos 5 dias após os tratamentos em 2005 e aos 3; 6 e aos 9 dias após o tratamento em 2006. O iprodione controlou a incidência e a severidade de M. fructicola e Rhizopus spp. O dicloran foi o tratamento mais eficiente para o controle do Rhizopus spp. e intermediário para M. fructicola. Os tratamentos com óleo de cravo e dióxido de cloro, na maior dose, reduziram a incidência de Rhizopus spp. e para severidade apresentaram resultados intermediários.The consumers demand are increasing with regard to the quality of in nature products. The rot, besides causing loss in production, reduce the quality of the product, interfering significantly in the marketing. The objective

  12. Os ditongos do latim ao português

    Directory of Open Access Journals (Sweden)

    Quednau, Laura Rosane

    2005-01-01

    Full Text Available O presente trabalho trata da evolução dos ditongos já existentes e do surgimento de novos ditongos do latim ao português, analisando a motivação de sua redução quando esta ocorre. Para tanto, apresentamos cada ditongo separadamente, trazendo informações sobre a sua forma em latim clássico, latim vulgar e português. Além disso, tratamos de outros processos de formação de ditongos em português, uma vez que o português possui um número maior de ditongos do que o latim. Por fim, apresentamos um quadro-resumo, sintetizando as informações mais importantes do trbalho: quais ditongos permaneceram, quais foram reduzidos, quais surgiram por outros processos e quais são as causas da formação de ditongos em português

  13. Arquitectura de peso. Do monumento ao (anti)monumento

    OpenAIRE

    Eva Patrícia da Silva Rocha Florindo

    2012-01-01

    Este ensaio reflecte sobre as raízes do conceito de monumento e a sua evolução ao longo dos tempos como forma de dar resposta à questão o que é quot;ser monumento hoje? A pertinência do tema fundamenta-se no paradoxo que acompanha a actual existência do monumento: embora continue muito presente na nossa sociedade é comummente negada a sua edificação, sendo-lhe atribuídas outras designações, como a de quot;ícone arquitectónico.Pretende-se assim desfazer o conflito moral que tem perseguido este...

  14. Lévi-Strauss nos 90 voltas ao passado

    Directory of Open Access Journals (Sweden)

    Lévi-Strauss Claude

    1998-01-01

    Full Text Available Este artigo responde às críticas formuladas por Christian Delacampagne e Bernard Traimond em "A Polêmica Sartre/Lévi-Strauss Revisitada. Nas Raízes das Ciências Sociais de Hoje", publicado em Les Temps Modernes 596 (novembro-dezembro de 1997. Para fazê-lo, recorda inicialmente o caráter relativo da oposição entre "sociedades frias" e "sociedades quentes". Em seguida, refuta a tese de que Maurice Merleau-Ponty, sob a capa de um elogio, teria dirigido críticas veladas ao autor. Finalmente, reconhecendo o afastamento da antropologia de hoje em face das posições do autor, admite, sem se pronunciar sobre o valor desse movimento, que temas de ar sartriano ressurgem nos antropólogos contemporâneos.

  15. Correla\\c{c}\\~ao de longa-dura\\c{c}\\~ao e anal\\'ise bayesiana da evolu\\c{c}\\~ao temporal dos terremotos ao longo da falha de samambaia, nordeste do brasil

    CERN Document Server

    de Freitas, D B; Pereira, L L S; Pedro, L S; Atanazio, M G N; Vilar, C S

    2013-01-01

    A Bayesian approach is adopted to analyze the sequence of seismic events and their magnitudes near Jo\\~ao C\\^amara which occurred mainly from 1983 to 1998 along the Samambaia fault. In this work, we choose a Bayesian model for the process of occurrence times conditional on the observed magnitude values following the same procedure suggested by Stavrakakis and Tselentis (1987). The model parameters are determined on the basis of historical and physical information. We generate posterior samples from the joint posterior distribution of the model parameters by using a variant of the Metropolis-Hastings algorithm. We use the results in a variety of ways, including the construction of pointwise posterior confidence bands for the conditional intensity of the point process as a function of time, as well as, a posterior distribuition as a function of the mean of occurrence per unit time.

  16. NFIRAOS First Facility AO System for the Thirty Meter Telescope

    CERN Document Server

    Herriot, Glen; Atwood, Jenny; Boyer, Corinne; Byrnes, Peter; Caputa, Kris; Ellerbroek, Brent; Gilles, Luc; Hill, Alexis; Ljusic, Zoran; Pazder, John; Rosensteiner, Matthias; Smith, Malcolm; Spano, Paolo; Szeto, Kei; Véran, Jean-Pierre; Wevers, Ivan; Wang, Lianqi; Wooff, Robert

    2014-01-01

    NFIRAOS, the Thirty Meter Telescope's first adaptive optics system is an order 60x60 Multi-Conjugate AO system with two deformable mirrors. Although most observing will use 6 laser guide stars, it also has an NGS-only mode. Uniquely, NFIRAOS is cooled to -30 C to reduce thermal background. NFIRAOS delivers a 2-arcminute beam to three client instruments, and relies on up to three IR WFSs in each instrument. We present recent work including: robust automated acquisition on these IR WFSs; trade-off studies for a common-size of deformable mirror; real-time computing architectures; simplified designs for high-order NGS-mode wavefront sensing; modest upgrade concepts for high-contrast imaging.

  17. Há alternativas ao uso dos transgênicos?

    Directory of Open Access Journals (Sweden)

    Hugh Lacey

    2007-07-01

    Full Text Available A existência ou não de alternativa ao uso de transgênicos capaz de satisfazer a demanda mundial por alimento e nutrientes é uma questão que permanece aberta à investigação científica. A importância dos transgênicos ainda não está bem fundamentada no conhecimento científico disponível, em parte porque as conquistas e o potencial da agroecologia não foram objeto de atenção científica suficiente.Whether or not there are alternatives to using transgenics, that would be able to satisfy the world's food and nutrition needs, remains open to further scientific investigation. The necessity for using transgenics is not currently well based on available scientific knowledge, in part because the achievements and potential of agroecology have received insufficient scientific attention.

  18. O prazer associado ao consumo de alimentos e factores influenciadores

    OpenAIRE

    Gomes, Filipe Gonçalo Ferreira

    2013-01-01

    Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências Farmacêuticas Os indivíduos quando sujeitos a várias sensações transmitem respostas que surgem de reacções fisiológicas resultantes de certos estímulos, gerando a interpretação das propriedades intrínsecas aos alimentos, sendo a análise sensorial realizada em função dessas respostas individuais. As sensações são medidas por efeitos psicológic...

  19. Há alternativas ao uso dos transgênicos?

    OpenAIRE

    Hugh Lacey

    2007-01-01

    A existência ou não de alternativa ao uso de transgênicos capaz de satisfazer a demanda mundial por alimento e nutrientes é uma questão que permanece aberta à investigação científica. A importância dos transgênicos ainda não está bem fundamentada no conhecimento científico disponível, em parte porque as conquistas e o potencial da agroecologia não foram objeto de atenção científica suficiente.Whether or not there are alternatives to using transgenics, that would be able to satisfy the world's...

  20. Virtópsia: o adeus ao bisturi?

    OpenAIRE

    Andrade, Sílvia da Luz Meneses Duarte de

    2015-01-01

    A investigação médico-legal atual tem cada vez mais ao seu dispor técnicas radiológicas que visam auxiliar o diagnóstico da causa de morte e mecanismos fisiopatológicos determinantes da mesma. Contudo, a dúvida levantada pela utilização desses métodos é se estes poderiam vir a ser substitutos da autópsia convencional, ou se apenas têm capacidade de ser implementados como adjuntos da mesma. Nesta revisão tentou-se focar os pontos a favor e contra de algumas das técnicas utilizadas, nomeadament...

  1. Introdução ao LaTeX

    Directory of Open Access Journals (Sweden)

    Eric Batista Ferreira

    2012-12-01

    Full Text Available O pacote de macros para o processamento de textos, LaTeX{}, que utiliza o TeX{} como principal ferramenta, é fundamental para a produção de textos matemáticos e científicos de alto nível e emph{layout} profissional. A necessidade de conhecê-los se torna ainda mais real para profissionais e estudantes das Ciências Exatas. Além de adequado para a notação Matemática, o LaTeX{} tem muitas outras vantagens, como ser gratuito, multiplataforma e livre de vírus. Por esses e outros motivos, o minicurso ``Introdução ao LaTeX{}'' foi ministrado na emph{I Semana da Matemática da Unifal-MG}, a convite de sua comissão organizadora.

  2. Reaching Out to Send a Message: Proteins Associated with Neurite Outgrowth and Neurotransmission are Altered with Age in the Long-Lived Naked Mole-Rat.

    Science.gov (United States)

    Triplett, Judy C; Swomley, Aaron M; Kirk, Jessime; Grimes, Kelly M; Lewis, Kaitilyn N; Orr, Miranda E; Rodriguez, Karl A; Cai, Jian; Klein, Jon B; Buffenstein, Rochelle; Butterfield, D Allan

    2016-07-01

    Aging is the greatest risk factor for developing neurodegenerative diseases, which are associated with diminished neurotransmission as well as neuronal structure and function. However, several traits seemingly evolved to avert or delay age-related deterioration in the brain of the longest-lived rodent, the naked mole-rat (NMR). The NMR remarkably also exhibits negligible senescence, maintaining an extended healthspan for ~75 % of its life span. Using a proteomic approach, statistically significant changes with age in expression and/or phosphorylation levels of proteins associated with neurite outgrowth and neurotransmission were identified in the brain of the NMR and include: cofilin-1; collapsin response mediator protein 2; actin depolymerizing factor; spectrin alpha chain; septin-7; syntaxin-binding protein 1; synapsin-2 isoform IIB; and dynamin 1. We hypothesize that such changes may contribute to the extended lifespan and healthspan of the NMR. PMID:26935741

  3. Relations between social status and the gonadotrophin-releasing hormone system in females of two cooperatively breeding species of African mole-rats, Cryptomys hottentotus hottentotus and Cryptomys hottentotus pretoriae: neuroanatomical and neuroendocrinological studies.

    Science.gov (United States)

    Du Toit, Lydia; Bennett, Nigel C; Katz, Arieh A; Kalló, Imre; Coen, Clive W

    2006-01-10

    In common (Cryptomys hottentotus hottentotus) and highveld (Cryptomys hottentotus pretoriae) mole-rats, reproduction is subject to two forms of regulation in addition to incest avoidance. These are the only social bathyergids known to restrict breeding to a particular season; furthermore, subordinate members of their colonies show suppressed reproduction throughout the year. Females from both species were assessed and compared for social and seasonal effects on the gonadotrophin-releasing hormone (GnRH) system. GnRH-immunoreactive (ir) structures were visualized immunohistochemically; GnRH content was determined by radioimmunoassay. In both species, GnRH-ir cell bodies and processes are loosely distributed along the septopreopticoinfundibular continuum, with dense fiber aggregations in the region of the organum vasculosum of the lamina terminalis and median eminence. The two species differ in the rostrocaudal distribution of their GnRH-ir cell bodies. In highveld mole-rats, most of these cells are in the septal/preoptic area; in common mole-rats, more than half of them are in the mediobasal hypothalamus. Compared with common mole-rats, highveld mole-rats have a greater total number of GnRH-ir cell bodies, higher GnRH content, and more intense GnRH immunoreactivity in the median eminence. Within highveld colonies, the nonreproductive females have larger GnRH-ir cell bodies, more intense GnRH immunoreactivity in the median eminence, and higher GnRH content than the reproductive females; these findings suggest inhibited release of GnRH in the nonreproductive, subordinate females. In contrast, in common mole-rat females, neither status nor season appears to affect the investigated parameters of the GnRH system; this suggests a predominantly behavioral basis to their suppressed reproduction.

  4. Assessing Animal Welfare Impacts in the Management of European Rabbits (Oryctolagus cuniculus), European Moles (Talpa europaea) and Carrion Crows (Corvus corone).

    Science.gov (United States)

    Baker, Sandra E; Sharp, Trudy M; Macdonald, David W

    2016-01-01

    Human-wildlife conflict is a global issue. Attempts to manage this conflict impact upon wild animal welfare, an issue receiving little attention until relatively recently. Where human activities harm animal welfare these effects should be minimised where possible. However, little is known about the welfare impacts of different wildlife management interventions, and opinions on impacts vary widely. Welfare impacts therefore need to be assessed objectively. Our objectives were to: 1) establish whether an existing welfare assessment model could differentiate and rank the impacts of different wildlife management interventions (for decision-making purposes); 2) identify and evaluate any additional benefits of making formal welfare assessments; and 3) illustrate issues raised by application of the model. We applied the welfare assessment model to interventions commonly used with rabbits (Oryctolagus cuniculus), moles (Talpa europaea) and crows (Corvus corone) in the UK. The model ranked interventions for rabbits (least impact first: fencing, head shot, chest shot) and crows (shooting, scaring, live trapping with cervical dislocation). For moles, managing molehills and tunnels scored least impact. Both spring trapping, and live trapping followed by translocation, scored greater impacts, but these could not be compared directly as they scored on different axes of the model. Some rankings appeared counter-intuitive, highlighting the need for objective formal welfare assessments. As well as ranking the humaneness of interventions, the model highlighted future research needs and how Standard Operating Procedures might be improved. The model is a milestone in assessing wildlife management welfare impacts, but our research revealed some limitations of the model and we discuss likely challenges in resolving these. In future, the model might be developed to improve its utility, e.g. by refining the time-scales. It might also be used to reach consensus among stakeholders about

  5. Assessing Animal Welfare Impacts in the Management of European Rabbits (Oryctolagus cuniculus), European Moles (Talpa europaea) and Carrion Crows (Corvus corone).

    Science.gov (United States)

    Baker, Sandra E; Sharp, Trudy M; Macdonald, David W

    2016-01-01

    Human-wildlife conflict is a global issue. Attempts to manage this conflict impact upon wild animal welfare, an issue receiving little attention until relatively recently. Where human activities harm animal welfare these effects should be minimised where possible. However, little is known about the welfare impacts of different wildlife management interventions, and opinions on impacts vary widely. Welfare impacts therefore need to be assessed objectively. Our objectives were to: 1) establish whether an existing welfare assessment model could differentiate and rank the impacts of different wildlife management interventions (for decision-making purposes); 2) identify and evaluate any additional benefits of making formal welfare assessments; and 3) illustrate issues raised by application of the model. We applied the welfare assessment model to interventions commonly used with rabbits (Oryctolagus cuniculus), moles (Talpa europaea) and crows (Corvus corone) in the UK. The model ranked interventions for rabbits (least impact first: fencing, head shot, chest shot) and crows (shooting, scaring, live trapping with cervical dislocation). For moles, managing molehills and tunnels scored least impact. Both spring trapping, and live trapping followed by translocation, scored greater impacts, but these could not be compared directly as they scored on different axes of the model. Some rankings appeared counter-intuitive, highlighting the need for objective formal welfare assessments. As well as ranking the humaneness of interventions, the model highlighted future research needs and how Standard Operating Procedures might be improved. The model is a milestone in assessing wildlife management welfare impacts, but our research revealed some limitations of the model and we discuss likely challenges in resolving these. In future, the model might be developed to improve its utility, e.g. by refining the time-scales. It might also be used to reach consensus among stakeholders about

  6. Assessing Animal Welfare Impacts in the Management of European Rabbits (Oryctolagus cuniculus, European Moles (Talpa europaea and Carrion Crows (Corvus corone.

    Directory of Open Access Journals (Sweden)

    Sandra E Baker

    Full Text Available Human-wildlife conflict is a global issue. Attempts to manage this conflict impact upon wild animal welfare, an issue receiving little attention until relatively recently. Where human activities harm animal welfare these effects should be minimised where possible. However, little is known about the welfare impacts of different wildlife management interventions, and opinions on impacts vary widely. Welfare impacts therefore need to be assessed objectively. Our objectives were to: 1 establish whether an existing welfare assessment model could differentiate and rank the impacts of different wildlife management interventions (for decision-making purposes; 2 identify and evaluate any additional benefits of making formal welfare assessments; and 3 illustrate issues raised by application of the model. We applied the welfare assessment model to interventions commonly used with rabbits (Oryctolagus cuniculus, moles (Talpa europaea and crows (Corvus corone in the UK. The model ranked interventions for rabbits (least impact first: fencing, head shot, chest shot and crows (shooting, scaring, live trapping with cervical dislocation. For moles, managing molehills and tunnels scored least impact. Both spring trapping, and live trapping followed by translocation, scored greater impacts, but these could not be compared directly as they scored on different axes of the model. Some rankings appeared counter-intuitive, highlighting the need for objective formal welfare assessments. As well as ranking the humaneness of interventions, the model highlighted future research needs and how Standard Operating Procedures might be improved. The model is a milestone in assessing wildlife management welfare impacts, but our research revealed some limitations of the model and we discuss likely challenges in resolving these. In future, the model might be developed to improve its utility, e.g. by refining the time-scales. It might also be used to reach consensus among

  7. Assessing Animal Welfare Impacts in the Management of European Rabbits (Oryctolagus cuniculus), European Moles (Talpa europaea) and Carrion Crows (Corvus corone)

    Science.gov (United States)

    Baker, Sandra E.; Sharp, Trudy M.; Macdonald, David W.

    2016-01-01

    Human-wildlife conflict is a global issue. Attempts to manage this conflict impact upon wild animal welfare, an issue receiving little attention until relatively recently. Where human activities harm animal welfare these effects should be minimised where possible. However, little is known about the welfare impacts of different wildlife management interventions, and opinions on impacts vary widely. Welfare impacts therefore need to be assessed objectively. Our objectives were to: 1) establish whether an existing welfare assessment model could differentiate and rank the impacts of different wildlife management interventions (for decision-making purposes); 2) identify and evaluate any additional benefits of making formal welfare assessments; and 3) illustrate issues raised by application of the model. We applied the welfare assessment model to interventions commonly used with rabbits (Oryctolagus cuniculus), moles (Talpa europaea) and crows (Corvus corone) in the UK. The model ranked interventions for rabbits (least impact first: fencing, head shot, chest shot) and crows (shooting, scaring, live trapping with cervical dislocation). For moles, managing molehills and tunnels scored least impact. Both spring trapping, and live trapping followed by translocation, scored greater impacts, but these could not be compared directly as they scored on different axes of the model. Some rankings appeared counter-intuitive, highlighting the need for objective formal welfare assessments. As well as ranking the humaneness of interventions, the model highlighted future research needs and how Standard Operating Procedures might be improved. The model is a milestone in assessing wildlife management welfare impacts, but our research revealed some limitations of the model and we discuss likely challenges in resolving these. In future, the model might be developed to improve its utility, e.g. by refining the time-scales. It might also be used to reach consensus among stakeholders about

  8. Effects of KOH:ZnCl{sub 2} mole ratio on the phase formation, morphological and inhibitive properties of potassium zinc phosphate (PZP) pigments

    Energy Technology Data Exchange (ETDEWEB)

    Askari, F. [Inorganic Pigment and Glazes Department, Institute for Color Science and Technology, Tehran 1668814811 (Iran, Islamic Republic of); Surface Coatings and Corrosion Department, Institute for Color Science and Technology, Tehran 1668814811 (Iran, Islamic Republic of); Ghasemi, E., E-mail: eghasemi@iust.ac.ir [Inorganic Pigment and Glazes Department, Institute for Color Science and Technology, Tehran 1668814811 (Iran, Islamic Republic of); Ramezanzadeh, B.; Mahdavian, M. [Surface Coatings and Corrosion Department, Institute for Color Science and Technology, Tehran 1668814811 (Iran, Islamic Republic of)

    2015-05-15

    Graphical abstract: This figure illustrates the inhibition mechanism. The film precipitation on the anodic and cathodic regions of the metal surface causes a drop in dissolution rate of steel. - Highlights: • We synthesized the ZP pigments via coprecipitation method. • Effect of KOH:ZnCl{sub 2} on phase formation, morphology and inhibitive performance of pigment. • KOH:ZnCl{sub 2} ratio is effective on phase formation and morphology of ZP pigments. • KZn{sub 2}H(PO{sub 4}){sub 2} phase showed superior corrosion inhibition behavior than KZnPO{sub 4}. - Abstract: Different types of potassium zinc phosphate (PZP) pigments were synthesized by a co-precipitation method. The PZPs were obtained through changing KOH:ZnCl{sub 2} mole ratio. The chemical composition of the pigments was studied by X-ray diffraction, Fourier transform infrared spectroscopy and scanning electron microscopy (SEM). Then, the extracts of the PZPs were prepared in 3.5% (w/w) NaCl solution. The inhibitive performance of the pigments was investigated by polarization technique and SEM surface analysis through dipping mild steel panels in the pigment extracts for different immersion times. Results showed that changing ZnCl{sub 2}/KOH mole ratio could influence formation of KZn{sub 2}H(PO{sub 4}){sub 2} and KZnPO{sub 4} phases. It was known that the KZn{sub 2}H(PO{sub 4}){sub 2} phase has a superior corrosion inhibition behavior in 3.5% NaCl solution than KZnPO{sub 4} phase.

  9. HNBR/AO80共混阻尼橡胶的结构和性能%Structure and Properties of Vulcanized HNBR/AO80 Damping Rubbers

    Institute of Scientific and Technical Information of China (English)

    王爽; 张继华; 赵云峰

    2013-01-01

    在氢化丁腈橡胶(HNBR)中添加受阻酚AO80,制备HNBR/AO80共混橡胶,以改善HNBR的阻尼性能.采用DMA和FTIR等方法研究了HNBR/AO80共混硫化体系结构和性能之间的关系,并通过热处理的方法,研究了该体系的稳定性.结果表明:由于AO80的羟基与HNBR的腈基间强氢键作用,使HNBR/AO80硫化体系具有较好的阻尼性能.而热处理后,硫化体系中一些与橡胶分子有氢键作用的AO80,会不断自聚形成AO80的富相区、结晶、长大,形成大的结晶聚集体,导致共混体系的阻尼性能不稳定.%In order to improve the damping properties of hydrogenated nitrilebutadiene rubber (HNBR ) ,3,9-bis[ 1, 1-dimethyl-21 {β-(3-tertbutyl-4-hydroxy-5-methylphenyl) propionyloxy} ethyl ] -2,4,8,10-tetraoxaspi-ro [ 5, 5 ] -undecane (AO80) were added into it to prepare the vulcanized HNBR/AO80 rubbers. The relationship between the damping properties and micro-structure of this blending system was characterized by DMA & FTIR. Then the stability of this system was studied by thermal treatment at 8011. The results showed good damping property of this blending system, which was due to the effect of intermolecular hydrogen bonds between the hydroxyl groups of AO80 and the nitrile groups of HNBR. But the damping property of this curing system become unstable after thermal treated because of the self polymerization of AO80. With the increasing of thermal treated time, large number of AO80 formed rich phase,crystallized,grewed up,then formed large crystallise aggregates.

  10. Role of P57 and Ki-67 protein in the differential diagnosis between partial and complete hydatidiform moles%P57和Ki-67在葡萄胎鉴别诊断中的作用

    Institute of Scientific and Technical Information of China (English)

    袁雪芹; 荆福祥; 袁雪英

    2011-01-01

    Objective To investigate the role of P57 and Ki-67 protein in the differential diagnosis of partial or complete hydatidiform mole. Methods Tissues of normal placental villi, partial hydatidiform mole, and complete hydatidiform mole ( 12 for each) were collected. Distribution and expression of P57 and Ki-67 proteins were detected by immunohistochemistrical assay. Results P57 expression was located in the nuclei of villous cytotrophoblasts and stromal cells. There was no significant difference in distribution of P57 positive cells between normal villi and partial hydatidiform mole. However,none of the complete hydatidiform mole exhibited P57-positive cells. The Ki-67 expression was observed in the nuclear of cytotrophoblastic cells within placental tissues. There were significant differences in Ki-67-positive rate among normal placenta villi, partial hydatidiform mole, and complete hydatidiform mole (P<0.05). The Ki-67-positive rate in complete hydatidiform mole was higher than that in partial hydatidiform mole (P < 0.01 ). Conclusion The combined use of P57 and Ki-67 protein examination might be helpful to distinguish the complete hydatidiform mole from the partial hydatidiform mole.%目的:探讨P57和Ki-67蛋白在完全性和部分性葡萄胎鉴别诊断中的作用.方法:分别收集正常胎盘绒毛、部分性葡萄胎和完全性葡萄胎石蜡标本各12例,应用免疫组织化学方法检测P57和Ki-67蛋白在这些病变中的分布及表达水平.结果:P57蛋白在正常绒毛及部分性葡萄胎组织中主要分布于绒毛的细胞滋养叶细胞及间质细胞,两组间阳性率未见明显差异;而在完全性葡萄胎中细胞滋养叶细胞及间质细胞P57表达缺失.Ki-67蛋白主要表达于绒毛的细胞滋养叶细胞.正常绒毛组、部分性葡萄胎组和完全性葡萄胎组Ki-67阳性细胞百分率比较差别具有统计学意义(P<0.05).结论:P57结合Ki-67免疫组织化学检测可有效鉴别完全性和部分性葡萄胎.

  11. Prediction of benign and invasive hydatidiform moles by scanning electron microscopical technique%应用扫描电镜技术预测良性与侵蚀性葡萄胎

    Institute of Scientific and Technical Information of China (English)

    张瑜; 魏家芳; 朱海涛; 张恩娣; 张海雁; 薛京华; 李芳; 刘健; 李向党

    2001-01-01

    AIM To investigate the practical value of scanning electronmicroscopical technique (SEMT) in the early diagnosis of benign and invasive hydatidiform moles. METHODS SEMT was performed to observe 90 cases with hydatidiform moles (60 cases with benign and 30 cases with invasive hydatidiform moles) and 10 cases with normal placental villis as the control. Set as the differential criterion for our study was the assay HCG (human chorionic gonadotropin) of both the blood and the urine of the patients. Those whose HCG of both the blood and the urine after hydatidiform moles did not drop to the normal level in 12 weeks were regarded as with the malignant moles. RESULTS ① HCG of both the blood and the urine of 60 benign hydatidiform moles decreased to the normal level (3.1 IU·L-1) in 12 weeks and that of 1 hydatidiform mole increased after 144 days (>3.1 IU·L-1). ② There was a significant difference in image between the benign and the invasive hydatidiform moles. On the surface of the benign hydatidiform moles, there were rich and evenly distributed microvilli, but on the surface of the invasive hydatidiform moles, the microvilli were mixed into irregular spots. CONCLUSION The above results indicate that SEMT can be used to predict the benign and invasive hydatidiform moles.%目的 探讨扫描电镜技术预测良性与侵蚀性葡萄胎的应用价值.方法 运用扫描电镜技术观察葡萄胎90例(良性60例,侵蚀性30例),以10例正常早期胎盘绒毛作对照.在研究方法上,我们把患者血、尿HCG(绒毛膜促性腺激素)测定作为本研究的监测指标,当葡萄胎后12wk血、尿HCG不下降至正常时视为恶性.结果 ①60例良性葡萄胎的血、尿HCG于葡萄胎后12wk内降至正常;30例侵蚀性葡萄胎中,29例HCG于葡萄胎后12wk内超过正常,另有1例于20+4wk超过正常.②良性与侵蚀性葡萄胎的扫描电镜图像有显著差别:良性葡萄胎绒毛表面的微绒毛丰富,分布

  12. Robo-AO KP: A new era in robotic adaptive optics

    Science.gov (United States)

    Riddle, Reed L.; Baranec, Christoph; Law, Nicholas M.; Kulkarni, Shrinivas R.; Duev, Dmitry; Ziegler, Carl; Jensen-Clem, Rebecca M.; Atkinson, Dani Eleanor; Tanner, Angelle M.; Zhang, Celia; Ray, Amy

    2016-01-01

    Robo-AO is the first and only fully automated adaptive optics laser guide star AO instrument. It was developed as an instrument for 1-3m robotic telescopes, in order to take advantage of their availability to pursue large survey programs and target of opportunity observations that aren't possible with other AO systems. Robo-AO is currently the most efficient AO system in existence, and it can achieve an observation rate of 20+ science targets per hour. In more than three years of operations at Palomar Observatory, it has been quite successful, producing technology that is being adapted by other AO systems and robotic telescope projects, as well as several high impact scientific publications. Now, Robo-AO has been selected to take over operation of the Kitt Peak National Observatory 2.1m telescope. This will give Robo-AO KP the opportunity to pursue multiple science programs consisting of several thousand targets each during the three years it will be on the telescope. One-sixth of the observing time will be allocated to the US community through the NOAO TAC process. This presentation will discuss the process adapting Robo-AO to the KPNO 2.1m telescope, the plans for integration and initial operations, and the science operations and programs to be pursued.

  13. O Atendimento ao Público nos Destacamentos Territoriais do Comando Territorial de Braga

    OpenAIRE

    Rodrigues, André

    2012-01-01

    O presente trabalho está subordinado ao tema: “O atendimento ao público nos Destacamentos Territoriais do Comando Territorial de Braga” e que visa esclarecer quais os fatores que contribuem para prestação de um atendimento ao público de qualidade. O atendimento ao público de qualidade é fundamental para a fomentação de uma boa imagem da GNR na sociedade. Para atingir esse nível de qualidade é necessário que as instalações da GNR e a predisposição dos militares sej...

  14. Decisões judiciais sobre acesso aos medicamentos em Pernambuco

    Directory of Open Access Journals (Sweden)

    Artur Stamford

    2012-10-01

    Full Text Available OBJETIVO: Analisar as decisões do sistema jurídico sobre acesso da população a medicamentos no Sistema Único de Saúde por via judicial quanto a critérios de decisão e eventuais pressões políticas e econômicas. MÉTODOS: Estudo documental descritivo e retrospectivo de abordagem qualitativa e quantitativa. A coleta de dados foi realizada na Superintendência Estadual de Assistência Farmacêutica de Pernambuco, utilizando-se como fontes de dados 105 ações judiciais e relatórios administrativos de janeiro a junho de 2009. Verificaram-se os medicamentos com pedido ou carta patente no banco de dados do Instituto Nacional de Propriedade Industrial para identificar a frequência das patentes nas ações judiciais. Os dados obtidos foram classificados conforme o Sistema Anatômico Terapêutico Químico. Para análise das decisões judiciais, foi utilizada a teoria dos sistemas sociais autopoiéticos. RESULTADOS: As ações judiciais somaram 134 medicamentos com valor estimado de R$ 4,5 milhões para atender aos tratamentos solicitados; 70,9% dos medicamentos estavam com carta patente ou pedido e se concentraram em três classes terapêuticas: antineoplásicos e moduladores imunológicos, aparelho digestório e metabolismo, órgãos dos sentidos. Foram identificadas seis ideias centrais com os critérios de decisão dos magistrados (Constituição Federal e prescrição médica e as pressões entre os sistemas do direito, da economia e da política quanto ao acesso a medicamentos. CONCLUSÕES: A análise das decisões judiciais fundamentadas na teoria dos sistemas sociais autopoiéticos permitiu identificar as estimulações mútuas (dependências entre o sistema do direito e demais sistemas sociais em relação à questão do acesso dos cidadãos aos medicamentos. Essas dependências foram representadas pela Constituição Federal e pela propriedade intelectual. A Constituição Federal e a prescrição médica foram identificadas como

  15. Cirurgia conservadora, radioterapia externa e reforço de dose com braquiterapia de alta taxa de dose: uma nova perspectiva no tratamento de sarcomas de partes moles do adulto Limb-sparing surgery, external beam radiotherapy and boost with high-dose rate brachytherapy: a new perspective for the treatment of soft tissue sarcomas in adults

    Directory of Open Access Journals (Sweden)

    Antonio Cássio Assis Pellizzon

    2002-03-01

    Full Text Available OBJETIVO: Avaliar a influência no controle local de pacientes adultos e portadores de sarcoma de partes moles em extremidades e submetidos a cirurgia conservadora do membro, com braquiterapia de alta taxa de dose (BATD como reforço para a radioterapia externa (RT. MATERIAL E MÉTODOS: Foram avaliados 16 pacientes tratados, de 1993 até 1999. A RT foi utilizada com finalidade pré ou pós-operatória (30--55 Gy e BATD com dose de 18--36 Gy (fx 3--6 Gy BID. Com base no modelo linear quadrático calculou-se a dose efetiva biológica ("biological effective dose" - BED para o tumor e comparou-se seu valor a dados da literatura internacional, que utiliza tratamentos com RT e braquiterapia de baixa taxa de dose (BBTD. RESULTADOS: Os valores médios e medianos da BED para os sarcomas de partes moles foram de 78,5 Gy7 e 80 Gy7. A análise univariada mostrou que a BED para o tumor, quando utilizada BATD, era semelhante ao valor de 83 Gy7 quando utilizada BBTD (p = 0,008. As taxas de controle local, sobrevida livre de doença e sobrevida global atuarial em cinco anos foram de 83,2%, 75% e 93,7%, respectivamente. CONCLUSÕES: A BATD, quando utilizada como método complementar no reforço de dose da RT no tratamento conservador dos sarcomas de partes moles, apresenta taxas de controle local equiparáveis às da literatura internacional; no entanto, estudos com número maior de pacientes e período maior de seguimento são ainda necessários para determinar o verdadeiro potencial da BATD em substituir a BBTD.PURPOSE: To evaluate the influence on local control in adult patients with soft tissue sarcomas of the limbs that underwent limb-sparing surgery and high-dose rate brachytherapy (HDRB in association with teletherapy. MATERIAL AND METHODS: Sixteen patients treated from 1993 to 1999 were reviewed. Teletherapy was used pre- or postoperatively (30--55 Gy in association with HDRB in a dose range of 18--36 Gy (fx 3--6 Gy BID. The linear quadratic model was

  16. Uso de antibióticos e leveduras para controle da podridão-mole em couve-chinesa Use of antibiotics and yeasts for controlling Chinese cabbage soft rot

    Directory of Open Access Journals (Sweden)

    MRF Mello

    2011-03-01

    Full Text Available A podridão-mole causada por Pectobacterium carotovorum subsp. carotovorum (Pcc pode ocorrer em plantios de couve-chinesa (Brassica pekinensis com até 67% de incidência. O trabalho visou avaliar a sensibilidade in vitro de Pcc a bactericidas, o efeito de Mycoshield® nas dosagens de 3,0 e 1,5 g L-1, e de leveduras a 10(8 cel/mL no controle da doença em casa de vegetação e em campo. As plantas foram pulverizadas com Mycoshield® (oxitetraciclina 20% e leveduras (Rh1 e Rh2 (Rhodotorula spp. e Sc1 (Saccharomyces cerevisae sete dias após o transplante, e inoculadas por picada com o isolado Pcc120, sete dias e 12 h após o tratamento, respectivamente. Em todos os experimentos foram avaliados os componentes epidemiológicos da doença. In vitro, 40 isolados de Pcc testados apresentaram resistência ao sulfato de cobre e sensibilidade a oxitetraciclina, estreptomicina, oxitetraciclina+estreptomicina e oxitetraciclina+sulfato de cobre, todos na concentração de 0,2 g L-1. Seis isolados de Pcc foram mais inibidos por Mycoshield® do que por Agri-Micina® (oxitetraciclina 1,5% + estreptomicina 15% ambos a 3,0 g L-1, não sendo inibidos por Kasumin® (casugamicina 2% (2,0 mL L-1. Em casa de vegetação, Mycoshield® (3,0 g L-1 reduziu a severidade e o índice de doença em até 47,4 e 19%; já a levedura Sc1 reduziu a severidade da doença e a área abaixo da curva de progresso da doença (AACPD em até 27,6 e 39,3%, respectivamente, enquanto Rh1 reduziu a AACPD em até 33,5%. Em campo, Mycoshield® reduziu o índice de doença (14,4% a severidade (15,5% e a AACPD (28,9%; enquanto que Rh1 reduziu o índice de doença (8,8% e Sc1 reduziu a AACPD (15,7%. Conclui-se que o Mycoshield® e as leveduras apresentaram baixa eficiência para controle da podridão-mole da couve-chinesa em campo.The soft rot caused by Pectobacterium carotovorum subsp. carotovorum (Pcc may occur in Chinese cabbage (Brassica pekinensis plantations presenting till 67% of incidence

  17. A Reflective Gaussian Coronagraph for ExAO: Laboratory Performance

    CERN Document Server

    Park, R; Siegler, N; Nielsen, E L; Stalcup, T; Park, Ryeojin; Close, Laird M.; Siegler, Nick; Nielsen, Eric L.; Stalcup, Thomas

    2006-01-01

    We report laboratory results of a coronagraphic test bench to assess the intensity reduction differences between a "Gaussian" tapered focal plane coronagraphic mask and a classical hard-edged "Top Hat" function mask at Extreme Adaptive Optics (ExAO) Strehl ratios of ~94%. However, unlike a traditional coronagraph design, we insert a reflective focal plane mask at 45 degree to the optical axis. We also used an intermediate secondary mask ("Mask_2") before a final image in order to block additional mask-edge diffracted light. The test bench simulates the 8.1m Gemini North telescope. It includes one spider vane, different mask radii (r= 1.9, 3.7, 7.4 lambda/D) and two types of reflective focal plane masks (hard-edged "Top Hat" and "Gaussian" tapered profiles). In order to investigate the relative performance of these competing coronagraphic designs with regard to extra-solar planet detection sensitivity, we utilize the simulation of realistic extra-solar planet populations (Nielson et al. 2006). With an appropri...

  18. Introdução ao Manual de Epicteto

    Directory of Open Access Journals (Sweden)

    Aldo Lopes Dinucci

    2012-01-01

    Full Text Available Trata-se da edição de divulgação de tradução do Manual de Epicteto realizada por Aldo Dinucci e Alfredo Julien. Epicteto, filósofo estoico grego nascido no ano 55 em Hierápolis, na Frígia, Ásia Menor (hoje Turquia, como Sócrates, nada escreveu. Seu pensamento nos chegou através de seu aluno Flávio Arriano (cidadão romano de origem grega, que compilou (possivelmente com auxílio da taquigrafia suas aulas em oito livros (As Diatribes de Epicteto, das quais quatro livros sobrevivem e constituiu o Encheirídion, termo que em grego significa "punhal, arma portátil ou livro portátil, manual". Este pequeno trabalho foi composto por Arriano tomando por base suas compilações das aulas de Epicteto. Consistindo num conjunto de apotegmas para que o seguidor do estoicismo tenha sempre ao alcance da mão os princípios para enfrentar as dificuldades da vida e vencê-las, o Encheirídion tornou célebre o nome de Epicteto.

  19. VALORES DO RNI DE PACIENTES SUBMETIDOS AO TRATAMENTO COM ANTICOAGULANTES

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    Simone Aparecida Matos de SOUZA

    2015-12-01

    Full Text Available Uma pesquisa exploratória de natureza qualitativa e quantitativa foi realizada durante o período de maio a agosto de 2013 no Laboratório de Análises Clínicas do Hospital das Clínicas localizado no município de Itaperuna, RJ. O objetivo foi analisar o perfil dos pacientes sob tratamento com anticoagulantes, demonstrando as potenciais variações nos valores da Relação Normalizada Internacional (RNI em comparação aos valores de referência bem como a frequência de realização de tais exames. Um questionário foi aplicado pouco antes da coleta do sangue, estabelecendo-se como critério de inclusão o uso de medicamentos anticoagulantes. Os resultados indicaram um total de 45 pacientes sob tratamento com anticoagulantes, sendo 32 do sexo feminino e 13 do sexo masculino. A maioria dos pacientes encontrava-se sob tratamento com o anticoagulante de uso oral varfarina e se encontrava com idade superior a 50 anos. O valor médio do RNI apresentou-se dentro dos limites considerados seguros, porém mais da metade dos pacientes apresentou RNI < 2,0 e a maioria dos pacientes sob tratamento com anticoagulantes não realiza a avaliação do RNI com frequência.

  20. Four year experience with the AO Anterior Thoracolumbar Locking Plate.

    Science.gov (United States)

    Thalgott, J S; Kabins, M B; Timlin, M; Fritts, K; Giuffre, J M

    1997-05-01

    For decades spinal surgeons have attempted to design simple, single stage anterior internal fixation systems for the thoracic and lumbar spine. Early devices presented both biomechanical and technical problems. The AO Anterior Thoracolumbar Locking Plate (ATLP) was designed to solve some of the problems encountered with early anterior instrumentation. The ATLP system is constructed in Commercially Pure titanium. It is a low profile device indicated for use for unstable burst fractures in the anterior column; metastatic tumor management; and degenerative diseases of the thoracolumbar spine between levels T10 and L5. Implantation of the device involves direct anterior decompression with sagittal reduction and corpectomy. This is followed by grafting reconstruction, and plate fixation. This device has been implanted in 25 patients with an average follow-up of 38 months. There were five (5) broken screws in three (3) patients, and no broken plates. Implant related postoperative complications included two misplaced screws. Preliminary results indicate that the ATLP system seems to be a safe, low profile, MRI/CT compatible device that provides definitive single stage fixation of the anterior spinal column. PMID:9160452

  1. INTRODUÇAO AOS MODELOS ODE PARTICIPAÇÃO DE MERCADO EM SERVIÇOS DE TRANSPORTES

    Directory of Open Access Journals (Sweden)

    Antonio Galvão Novaes

    2010-04-01

    Full Text Available

    Análises de participação de mercado ("market share" são comuns em estudos na área de "marketing", envolvendo produtos e respectivas marcas, de um lado, o perfil da demanda de outro, e o posicionamento das empresas produtoras que competem nesse mercado, num terceiro bloco. No setor de transportes a literatura registra aplicações em ligações aéreas e em serviços intermunicipais de ônibus. Os modelos de participação de mercado se aplicam normalmente a situações em que os operadores oferecem serviços de transportes similares num determinado mercado, com a competição sendo feita não com base em atributos modais intrínsecos, mas sim apoiada em características diferenciadoras intra-modais mais tênues, tais como conforto, atendimento, promoções tarifárias, "marketing" e propaganda, etc. Neste artigo é feita uma introdução aos modelos de "market share" em transportes, com a apresentação de um exemplo de aplicação ao transporte intermunicipal de passageiros em ônibus, sendo discutidos também aspectos ligados a calibração e tais modelos.

    ABSTRACT

    Market share analysis is common in marketing studies involving products and respective brands, on one hand, the demand profile on the other hand, and the competiting industries on a third set. In the transport sector the literature registers a number of applications to air transport problems and to intercity bus services. Market share models are normally applied to situations in which operators offer, in a specific market, transport services that are similar in nature, with competition based not on intrinsic modal attributes, but rather on more tenous intra-mode differentiating characteristics, such as comfort, attendance, tariff promotions, marketing and advertising efforts, etc (sub-modal configurations. It is presented in this paper an introduction to market share modelling in transport, with an example concerning an intercity bus service in

  2. Sexual maturity and litter size in short-tailed mole rat Nesokia indica%印度地鼠的性成熟和窝仔数

    Institute of Scientific and Technical Information of China (English)

    Rubina ARSHAD; Mirza Azhar BEG

    2004-01-01

    The breeding pattern of 348 short-tailed mole rats Nesokia indica inhabiting the non-crop areas of the central Punjab (Pakistan) was studied for effective vertebrate pest control. Of 107 males and 241 females trapped, 75 and 179,respectively, were sexually mature. The sex ratio revealed a predominance of females. Body weight and body length were used as indices of age of the trapped specimens of the short-tailed mole rat. The smallest sexually mature male rats were recorded in the body weight class 70 - 89 g and body length class 13.1 - 14.0 cm. The smallest sexually mature females were found in the body weight class 70 - 89 g and the body length class 12.1 - 13.0 cm. The average number of embryos in a litter size was 2.74 ± 0.15 (range, 1 - 5), whereas the average number of placental scars was 4.29 ± 0.19(1 - 11 ). Body weight classes appeared to have significant effect on litter size, whereas body length classes and estimated age had no significant effect on the size of litter. Pest control could be most effective when rats are reproductively inactive and are not breeding [Acta Zoologica Sinica 50 (5): 723-729, 2004].%为有效地进行有害脊椎动物的控制,研究了栖息于巴基斯坦Punjab中部的348只印度地鼠的繁殖模式.在所捕捉到的107雄鼠和241只雌鼠中,分别有75只和179只是性成熟的个体.性比偏雌.使用被捕个体标本的体重和体长作为指标,发现最小的性成熟的雄性个体体重为70-89 g,体长13.1-14.0 cm;一窝仔里面的平均胚胎数为2.74±0.15(范围,1-5),而平均胎斑数为4.29±0.19(1-11).体重似乎对窝仔数有显著影响,而体长和估计的年龄对窝仔数没影响.当老鼠繁殖不活跃和不繁殖时,控制害兽最有效[动物学报50(5):723 729,2004].

  3. 完全性葡萄胎与胎儿共存临床研究%Clinical study of complete hydatidiform mole and co-existing fetus

    Institute of Scientific and Technical Information of China (English)

    李珠玉; 陈海天; 彭软; 王子莲; 游泽山

    2015-01-01

    Objective To explore the clinical characteristics and pregnancy outcomes of complete hy-datidiform mole and co-existing fetus (CMCF).Methods The data of six CMCF women were analyzed retro-spectively.Results Among six CMCF women,five were pregnant after in vitro fertilization and embryo trans-plantation,and one after ovulation-stimulating treatment.Five patients were diagnosed with CMCF in middle pregnancy and one in early pregnancy.Five cases had twin pregnancy with complete hydatidiform mole and one was triplet pregnanct.One case insisted on continuous pregnancy,four accepted pregnancy termination and one was forced to terminate pregnancy.All six women and one fetus survived.Conclusions The incidence of CM-CF is probably correlated with the application of assisted reproductive technology.Clinical outcomes depend on disease progression,fetal chromosome and patients’willingness.If the fetal chromosome is normal and no seri-ous maternal complications occur during pregnancy,the fetus may survive.However,the risk of continuous pregnancy remains to be evaluated.%目的:探讨完全性葡萄胎与胎儿共存(CMCF)的临床特征及妊娠结局。方法收集并分析6例 CMCF 的临床资料。结果6例中,体外受精-胚胎移植术后妊娠5例,促排卵治疗后妊娠1例;妊娠中期发现5例,妊娠早期发现1例;双胎之一完全性葡萄胎5例,三胎之一完全性葡萄胎1例;要求继续妊娠1例,要求终止妊娠4例,被迫终止妊娠1例。6例产妇均存活,胎儿存活1例。结论CMCF 的发生可能与应用辅助生殖技术相关,其结局取决于病情发展、胎儿染色体及患者意愿。若胎儿染色体正常,且妊娠期间未出现严重母体并发症,有分娩活胎可能,但其继续妊娠的风险评估仍需进一步的研究。

  4. Patterns of Impairments in AOS and Mechanisms of Interaction between Phonological and Phonetic Encoding

    Science.gov (United States)

    Laganaro, Marina

    2012-01-01

    Purpose: One reason why the diagnosis of apraxia of speech (AOS) and its underlying impairment are often debated may lie in the fact that most patients do not display pure patterns of AOS. Mixed patterns are clearly acknowledged at other levels of impairment (e.g., lexical-semantic and lexical-phonological), and they have contributed to debate…

  5. Data of evolutionary structure change: 1AO5B-1ELCA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1AO5B-1ELCA 1AO5 1ELC B A VVGGFNCEKNSQPWQVAVYYQ----KEHICGGVLLDRNW...TPTWQKPDDLQCVFITLLPNENCAKV--YLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPV-PCGKPGVPAIYTNLIKFNSWIKDTMMKNA TRP CA 491 1ELC A 1ELCA...hain> 1ELC A 1ELCA PLHCLVNGQYAVHG... PRO CA 225 1ELC A 1ELCA

  6. Optimal control strategy to reduce the temporal wavefront error in AO systems

    NARCIS (Netherlands)

    Doelman, N.J.; Hinnen, K.J.G.; Stoffelen, F.J.G.; Verhaegen, M.H.

    2004-01-01

    An Adaptive Optics (AO) system for astronomy is analysed from a control point of view. The focus is put on the temporal error. The AO controller is identified as a feedback regulator system, operating in closed-loop with the aim of rejecting wavefront disturbances. Limitations on the performance of

  7. Freshwater Bryozoa (Phylactolaemata) from Curaçao, Aruba and Bonaire

    NARCIS (Netherlands)

    Lacourt, A.W.

    1955-01-01

    The Phylactolaemata-fauna of Curaçao, Aruba and Bonaire, as it appears from the samples collected by dr P. Wagenaar Hummelinck, is connected with the fauna of the South-American mainland. The material belongs to three species only: Hyalinella agilis — Curaçao, Aruba, Bonaire — in temporary or semi-p

  8. The nature of ethnic identity among the people of Curaçao

    NARCIS (Netherlands)

    Dijs, N.M. van der

    2011-01-01

    This qualitative research explores the nature of ethnic identity among the people of Curaçao. The questions that are of fundamental interest to this study are: how do the people of Curaçao perceive themselves ethnically, how do they experience their sense of belonging to an ethnic group and what fac

  9. O sindicalismo mineiro frente aos desafios dos anos 90

    Directory of Open Access Journals (Sweden)

    Antônio Carvalho Neto

    2000-12-01

    Full Text Available O que se analisa neste artigo é como os sindicatos dos bancários, metalúrgicos e trabalhadores em telecomunicações têm negociado o (desemprego, a demanda por qualificação e a remuneração variável. Foram tabuladas/analisadas 3.569 cláusulas de acordos coletivos, e realizadas 26 entrevistas com dirigentes sindicais e empresariais em três Estados (RJ, SP e MG. Os resultados indicam que as mudanças organizacionais foram incomparavelmente mais negociadas no setor metalúrgico do ABC. A flexibilização da jornada foi trocada pela redução (da jornada sem redução de salário nos setores metalúrgicos paulistas, mas não em Minas Gerais. No setor bancário, houve poucos resultados nas negociações sobre jornada. As negociações em torno da remuneração variável vinculada às metas das empresas aconteceram nos setores metalúrgicos, e não nos setores de serviços. As entrevistas apontam para um sindicalismo mais propositivo, no sentido de uma intervenção negociada, predisposição que não é correspondida pelos empresários, grosso modo. O Estado, que poderia utilizar seu poder regulador para induzir os empresários a negociarem nessa direção não tem produzido resultados satisfatórios. Conclui-se que não há maturidade empresarial no Brasil que permita ao Estado ausentar-se das relações de trabalho.

  10. A reflective Gaussian coronagraph for ExAO: laboratory performance

    Science.gov (United States)

    Park, Ryeojin; Close, Laird M.; Siegler, Nick; Nielsen, Eric L.; Stalcup, Thomas

    2006-06-01

    We report laboratory results of a coronagraphic testbed to assess the intensity reduction differences between a "Gaussian" tapered focal plane coronagraphic mask and a classical hard-edged "Top Hat" function mask at Extreme Adaptive Optics (ExAO) Strehl ratios of ~94%. However, unlike a traditional coronagraph design, we insert a reflective focal plane mask at 45 ° to the optical axis and used a "spot of Arago blocker" (axicon stop) before a final image in order to block additional mask edge-diffracted light. The testbed simulates the optical train of ground-based telescopes (in particular the 8.1m Gemini North telescope) and includes one spider vane and different mask radii (r= 1.9λ/D, 3.7λ/D, 7.4λ/D) and two types of reflective focal plane masks (hard-edged "Top Hat" and "Gaussian" tapered profiles). In order to investigate the performance of these competing coronagraphic designs with regard to extra-solar planet detection sensitivity, we utilize the simulation of realistic extra-solar planet populations (Nielsen et al. 2006). With an appropriate translation of our laboratory results to expected telescope performance, a "Gaussian" tapered mask radius of 3.7λ/D with an axicon stop performs best (highest planet detection sensitivity). For a full survey with this optimal design, the simulation predicts ~30% more planets detected compared to a similar sized "Top Hat" function mask with an axicon stop. Using the best design, the "point contrast ratio" between the stellar PSF peak and the coronagraphic PSF at 10λ/D (0.4" in H band if D = 8.1m) is 1.4 x 10 6. This is ~10 times higher than a classical Lyot "Top Hat" coronagraph.

  11. Das montanhas mexicanas ao ciberespaço

    Directory of Open Access Journals (Sweden)

    Ortiz Pedro Henrique Falco

    2005-01-01

    Full Text Available ESTE ARTIGO faz uma apanhado histórico contextualizado e uma análise comunicacional sobre o Exército Zapatista de Libertação Nacional - EZLN, que apareceu publicamente no estado mexicano de Chiapas em janeiro de 1994, a partir de sua origem indígena, com as demandas seculares dessa parcela da população marginalizada, suas peculiaridades e sua prática política, que o fazem um grupo armado bastante original dentro do contexto das lutas populares na América Latina. As estratégias políticas e de comunicação do EZLN são diferenciais importantes em relação a outras experiências guerrilheiras anteriores. Assim, analisamos também a habilidade que os zapatistas tiveram - e ainda têm - para conquistar espaço nos meios de comunicação convencionais e criar uma eficiente rede de solidariedade e comunicação, combinando as tradições seculares das comunidades indígenas, que são suas bases, aos recursos tecnológicos de meios eletrônicos como a Internet e a Web. Esta combinação criativa de iniciativas políticas bem-sucedidas, bases sociais resistentes, diálogo permanente com a chamada sociedade civil - nacional e internacional - e vitórias importantes no campo da comunicação, compensam a fragilidade militar do EZLN e possibilitam sua continuidade, mesmo no contexto militar bastante adverso em que se situa o conflito chiapaneco.

  12. Biomonitoring of the genotoxic effects and oxidative potentials of commercial edible dung beetles (Onitis sp.), grasshopper (Caelifera sp.) and mole crickets (Gryllotalpa sp.) in vitro.

    Science.gov (United States)

    Koc, Kubra; Incekara, Umit; Turkez, Hasan

    2014-09-01

    In this investigation, the genotoxic and oxidative effects of water soluble extracts of dung beetles, flying grasshopper and mole crickets have been assessed on cultured human blood cells. The extracts were added to the culture tubes at 12 different concentrations (0-2000 ppm). Micronucleus test was used to monitor the DNA and the chromosomal damage produced by aqueous extracts in vitro. In addition, to assess the oxidative effects, total antioxidant capacity (TAC) and total oxidant status (TOS) levels were also measured. Our results indicated that these extracts did not show genotoxic effects at the tested concentrations. However, the extracts caused dose-dependent alterations in both TAC and TOS levels. Based on the findings, it was concluded that the studied insects can be consumed safely, but it is necessary to consider the cellular damages which are likely to appear depending on oxidative stress at higher concentrations. It has also been suggested that this in vitro approach for oxidative and genotoxicity assessments may be useful to evaluate the potential health risks of edible insects. PMID:24700298

  13. Mapping intercellular CO2 mole fraction (Ci) in rosa rubiginosa leaves fed with abscisic acid by using chlorophyll fluorescence imaging. Significance Of ci estimated from leaf gas exchange

    Science.gov (United States)

    Meyer; Genty

    1998-03-01

    Imaging of photochemical yield of photosystem II (PSII) computed from leaf chlorophyll fluorescence images and gas-exchange measurements were performed on Rosa rubiginosa leaflets during abscisic acid (ABA) addition. In air ABA induced a decrease of both the net CO2 assimilation (An) and the stomatal water vapor conductance (gs). After ABA treatment, imaging in transient nonphotorespiratory conditions (0.1% O2) revealed a heterogeneous decrease of PSII photochemical yield. This decline was fully reversed by a transient high CO2 concentration (7400 mol mol-1) in the leaf atmosphere. It was concluded that ABA primarily affected An by decreasing the CO2 supply at ribulose-1,5-bisphosphate carboxylase/oxygenase. Therefore, the An versus intercellular mole fraction (Ci) relationship was assumed not to be affected by ABA, and images of Ci and gs were constructed from images of PSII photochemical yield under nonphotorespiratory conditions. The distribution of gs remained unimodal following ABA treatment. A comparison of calculations of Ci from images and gas exchange in ABA-treated leaves showed that the overestimation of Ci estimated from gas exchange was only partly due to heterogeneity. This overestimation was also attributed to the cuticular transpiration, which largely affects the calculation of the leaf conductance to CO2, when leaf conductance to water is low. PMID:9501127

  14. Transmission Characteristics of MOLED Containing Negative Refractive Index Dielectric Layer%带负折射介质层的MOLED传输特性的模拟研究

    Institute of Scientific and Technical Information of China (English)

    张剑华; 刘琼; 李宏建

    2010-01-01

    分析了由正负折射率介质交替构成的分布式布拉格反射镜(DBR)的复有效折射率及其色散关系,并将其与由折射率不同的正折射率介质交替构成的DBR进行了比较;研究了由这种DBR和金属做反射镜的微腔有机发光器件(MOLED)的光学传输特性,发现这种器件具有很好的滤波功能且可使器件薄化;计论了这种MOLED的谐振波长和归一化电致发光(EL)谱随观测角的变化关系.这些工作为进一步提高微腔OLED的发光色纯度、减小其腔长提供了新方法.

  15. N2 Mole Fraction Dependence of Plasma Bullet Propagation in Premixed He/N2 Plasma Needle Discharge at Atmospheric Pressure

    Science.gov (United States)

    Ni, Gengsong; Qian, Muyang; Yang, Congying; Liu, Sanqiu; Wang, Dezhen

    2016-07-01

    In this work, a computational modeling study on the mechanism of the acceleration behavior of a plasma bullet in needle-plane configuration is presented. Above all, in our model, two sub-models of time-dependent plasma dynamics and laminar flow are connected using a oneway coupled method, and both the working gas and the surrounding gas around the plasma jet are assumed to be the same, which are premixed He/N2 gas. The mole fractions of the N2 (NMF) ingredient are set to be 0.01%, 0.1% and 1% in three cases, respectively. It is found that in each case, the plasma bullet accelerates with time to a peak velocity after it exits the nozzle and then decreases until getting to the treated surface, and that the velocity of the plasma bullet increases at each time moment with the peak value changing from 0.72×106 m/s to 0.80×106 m/s but then drops more sharply when the NMF varies from 0.01% to 1%. Besides, the electron impact ionizations of helium neutrals and nitrogen molecules are found to have key influences on the propagation of a plasma bullet instead of the penning ionization. supported by National Natural Science Foundation of China (No. 11465013), the Natural Science Foundation of Jiangxi Province, China (No. 20151BAB212012), and in part by the International Science and Technology Cooperation Program of China (No. 2015DFA61800)

  16. Overexpression of the hydatidiform mole-related gene F10 inhibits apoptosis in A549 cells through downregulation of BCL2-associated X protein and caspase-3.

    Science.gov (United States)

    Song, Yali; Zhang, Gong; Zhu, Xiulan; Pang, Zhanjun; Xing, Fuqi; Quan, Song

    2012-09-01

    The aim of this study was to investigate how the overexpression of the hydatidiform mole-related gene F10 affects apoptosis in human lung cancer A549 cells. A549 cells were transfected with pEGFP-N1-F10 (A549-F10) or pEGFP-N1 empty vector (A549-empty). Untransfected A549, A549-F10 or A549-empty cells were examined using the MTT cell proliferation assay and the TUNEL-FITC/Hoechst 33258 apoptosis assay. Western blotting was used to examine the expression levels of the pro-apoptotic genes, BCL2-associated X protein (BAX) and caspase-3. F10 was stably expressed in A549 cells. From 12 h, A549-F10 cells proliferated markedly faster than the untransfected and A549-empty cells. F10 overexpression also significantly inhibited apoptosis, as shown by the reduced number of TUNEL and Hoechst 33258 double-positive cells. This inhibition was likely due to an F10-induced reduction in the BAX and caspase-3 levels. The results of this study indicate that F10 overexpression inhibits apoptosis in A549 cells through the downregulation of the pro-apoptotic genes BAX and caspase-3. PMID:23741243

  17. Facile synthesis of multi-shell structured binary metal oxide powders with a Ni/Co mole ratio of 1:2 for Li-Ion batteries

    Science.gov (United States)

    Choi, Seung Ho; Park, Sun Kyu; Lee, Jung-Kul; Kang, Yun Chan

    2015-06-01

    Multi-shell structured binary transition metal oxide powders with a Ni/Co mole ratio of 1:2 are prepared by a simple spray drying process. Precursor powder particles prepared by spray drying from a spray solution of citric acid and ethylene glycol have completely spherical shape, fine size, and a narrow size distribution. The precursor powders turn into multi-shell powders after a post heat-treatment at temperatures between 250 and 800 °C. The multi-shell structured powders are formed by repeated combustion and contraction processes. The multi-shell powders have mixed crystal structures of Ni1-xCo2O4-x and NiO phases regardless of the post-treatment temperature. The reversible capacities of the powders post-treated at 250, 400, 600, and 800 °C after 100 cycles are 584, 913, 808, and 481 mA h g-1, respectively. The low charge transfer resistance and high lithium ion diffusion rate of the multi-shell powders post-treated at 400 °C with optimum grain size result in superior electrochemical properties even at high current densities.

  18. Sex, Status, and Sand: California Academy of Sciences' Teen Interns Examine Trends of the Pacific Mole Crab (Emerita analoga) at Ocean Beach, San Francisco

    Science.gov (United States)

    Chu, J. B.; Conrad-Saydah, A.; Cohen, S.; Tom, R.; Robins-Moloney, M.; Masters, D.; Mason, K.; Alfaro, F.

    2003-12-01

    Student interns from the California Academy of Sciences' Careers in Sciences program monitored the Pacific mole crab (Emerita analoga), or sand crabs, in collaboration with the Farallones Marine Sanctuary Association. These small crustaceans live in the swash zone of the sandy beach habitat. Sand crabs are important in the food web, and therefore their status can help indicate the health of the larger environment. The interns helped the Gulf of the Farallones National Marine Sanctuary by monitoring the abundance and distribution of sand crabs at Ocean Beach in San Francisco, California. Students set up transects perpendicular to the shoreline, collected 10 samples along the transect, measured the carapace length, determined the sex of each crab, and checked for the presence of eggs. Students monitored June through September, 2003. Trends examined included differences in the gender ratio, size frequency, and distribution along the beach. Students also compared their data to other student data taken from other sites in San Francisco and Marin counties during 2001-2003 from the online database at http://www.sandcrabs.org. Using comparisons, interns were able to better understand the processes and significance of studying marine species. Implementation of the project was invaluable in aiding the interns in their understanding of the natural sciences and the role of monitoring habitats in environmental health.

  19. Biomonitoring of the genotoxic effects and oxidative potentials of commercial edible dung beetles (Onitis sp.), grasshopper (Caelifera sp.) and mole crickets (Gryllotalpa sp.) in vitro.

    Science.gov (United States)

    Koc, Kubra; Incekara, Umit; Turkez, Hasan

    2014-09-01

    In this investigation, the genotoxic and oxidative effects of water soluble extracts of dung beetles, flying grasshopper and mole crickets have been assessed on cultured human blood cells. The extracts were added to the culture tubes at 12 different concentrations (0-2000 ppm). Micronucleus test was used to monitor the DNA and the chromosomal damage produced by aqueous extracts in vitro. In addition, to assess the oxidative effects, total antioxidant capacity (TAC) and total oxidant status (TOS) levels were also measured. Our results indicated that these extracts did not show genotoxic effects at the tested concentrations. However, the extracts caused dose-dependent alterations in both TAC and TOS levels. Based on the findings, it was concluded that the studied insects can be consumed safely, but it is necessary to consider the cellular damages which are likely to appear depending on oxidative stress at higher concentrations. It has also been suggested that this in vitro approach for oxidative and genotoxicity assessments may be useful to evaluate the potential health risks of edible insects.

  20. Microhabitat types promote the genetic structure of a micro-endemic and critically endangered mole salamander (Ambystoma leorae) of Central Mexico.

    Science.gov (United States)

    Sunny, Armando; Monroy-Vilchis, Octavio; Reyna-Valencia, Carlos; Zarco-González, Martha M

    2014-01-01

    The reduced immigration and emigration rates resulting from the lack of landscape connectivity of patches and the hospitality of the intervening matrix could favor the loss of alleles through genetic drift and an increased chance of inbreeding. In order for isolated populations to maintain sufficient levels of genetic diversity and adapt to environmental changes, one important conservation goal must be to preserve or reestablish connectivity among patches in a fragmented landscape. We studied the last known population of Ambystoma leorae, an endemic and critically threatened species. The aims of this study were: (1) to assess the demographic parameters of A. leorae and to distinguish and characterize the microhabitats in the river, (2) to determine the number of existing genetic groups or demes of A. leorae and to describe possible relationships between microhabitats types and demes, (3) to determine gene flow between demes, and (4) to search for geographic locations of genetic discontinuities that limit gene flow between demes. We found three types of microhabitats and three genetically differentiated subpopulations with a significant level of genetic structure. In addition, we found slight genetic barriers. Our results suggest that mole salamander's species are very sensitive to microhabitat features and relatively narrow obstacles in their path. The estimates of bidirectional gene flow are consistent with the pattern of a stepping stone model between demes, where migration occurs between adjacent demes, but there is low gene flow between distant demes. We can also conclude that there is a positive correlation between microhabitats and genetic structure in this population. PMID:25076052

  1. Óleos essenciais e extratos vegetais no controle da podridão mole em alface crespa Essential oils and plant extracts on the control of soft rot of crispy lettuce

    Directory of Open Access Journals (Sweden)

    Cristiane L Silva

    2012-12-01

    Full Text Available Avaliou-se o efeito de óleos essenciais e extratos vegetais no controle da podridão mole em alface, bem como, a influência desses produtos nas características físico-químicas desta hortaliça. Nos testes in vitro, discos de papel de filtro foram embebidos em 11 óleos essenciais e 20 extratos vegetais nas concentrações 0,0; 0,25; 0,50; 0,75 e 1% e 0,0; 10, 40, 70 e 100%, respectivamente, e depositados sobre meio de cultura contendo Pectobacterium carotovorum subsp. carotovorum (Pcc A1. Os halos de inibição foram mensurados após 24 e 48 h de incubação. Em casa de vegetação, plantas de alface cv. Veneranda foram tratadas com 11 óleos nas concentrações de 0,5 e 1%, 20 extratos na concentração de 10% e Mycoshield® (3 g L-1, sendo inoculadas com o isolado Pcc A1 após 72 h. A severidade da doença foi avaliada a intervalos de seis até 48 h, calculando-se a área abaixo da curva de progresso da doença (AACPD. Em experimento similar, plantas tratadas com óleo de Corymbia citriodora, sete extratos e Mycoshield® foram analisadas quanto aos teores de sólidos solúveis, vitamina C, acidez titulável e pH. Pcc A1 não foi inibido in vitro. Dois óleos (C. citriodora e Citrus sinensis e sete extratos (Parkinsonia aculeata, Chamaecrista cytisoides, Sida galherensis, Polygala violaceae, Chamaecrista desvauxii e Pityrocarpa moniliformis reduziram significativamente a severidade da doença em relação à testemunha, não diferindo do controle Mycoshield®. Já a AACPD foi reduzida por oito óleos e dez extratos. Destacaram-se com eficiência similar ao Mycoshield® e diferindo da testemunha (7,5 e 132,3 nas duas variáveis analisadas, o óleo de C. citriodora a 0,5% e o extrato de S. galherensis a 10% com severidades de 3,6 e 3,5 e AACPD de 83,35 e 88,25, respectivamente. Os teores de vitamina C, acidez titulável e pH não foram alterados em folhas de alface tratadas com óleo de C. citriodora e extratos de P. aculeata e C. cytisoides

  2. Common Moles, Atypical Moles (Dysplastic Nevi), and Risk of Melanoma

    Science.gov (United States)

    ... describes the features of early melanoma ( 2 , 5 ): Asymmetry . The shape of one half does not match ... Twitter Instagram YouTube Google+ LinkedIn GovDelivery RSS CONTACT INFORMATION Contact Us LiveHelp Online Chat MORE INFORMATION About ...

  3. Sobre a domiciliaçao dos triatomineos

    Directory of Open Access Journals (Sweden)

    Mário B. Aragão

    1981-06-01

    Full Text Available Foram reunidos resultados de testes de precipitina feitos com o conteúdo do tubo digestivo de triatomineos. €ssas informações foram discutidas com base nas proporções de sangue de mamíferos e de ave, encontradas e em diversas observações relativas às espécies de vertebrados a que os triatomíneos estão associados na natureza. O estudo englobou as seguintes espécies: Belminus peruvianus, Panstrongylus geniculatus, Panstrongilus herreri, Panstrongylus megistus, Psammolestes tertius, Rhodnius neglectus, Rhodnius prolixus,Triatoma arthurneivai, Triatoma dimidiata,Triatoma infestans, Triatoma protracta, Triatoma rubrovaria e Triatoma sórdida. As seguintes conclusões puderam ser obtidas: 1 - As espécies que, nos biótopos artificiais, se alimentam principalmente de sangue humano, na natureza, são as mais ecléticas. Sugam mamífero, ave e animais de sangue-frio, mas apresentam marcada preferência por sangue de mamífero. 2 - As espécies que, nos biótopos artificiais, são encontradas com maior freqüência associadas a aves, na natureza ou preferem sangue de ave ou não tem predileção nítida por ave ou mamífero. 3 - As espécies associadas a animais de sangue frio ou restritas a um único grupo de mamíferos, podem colonizar nos domicílios desde que eles sejam previamente colonizados pelo hospedeiro. 4 - Não foram encontrados indícios de que alguma espécie esteja se adaptando aos domicílios. Todos os triatomineos ditos domiciliários já possuíam, na natureza, atributos que permitiam a vida em novos biótopos, habitados ou pelo homem ou por animais domésticos.

  4. SCExAO as a precursor to an ELT exoplanet direct imaging instrument

    CERN Document Server

    Jovanovic, Nemanja; martinache, Frantz; Clergeon, Christophe; Singh, Garima; Vievard, Sebastien; Kudo, Tomoyuki; Garrel, Vincent; Norris, Barnaby; Tuthill, Peter; Stewart, Paul; huby, Elsa; Perrin, Guy; Lacour, Sylvestre

    2013-01-01

    The Subaru Coronagraphic Extreme AO (SCExAO) instrument consists of a high performance Phase Induced Amplitude Apodisation (PIAA) coronagraph combined with an extreme Adaptive Optics (AO) system operating in the near-infrared (H band). The extreme AO system driven by the 2000 element deformable mirror will allow for Strehl ratios >90% to be achieved in the H-band when it goes closed loop. This makes the SCExAO instrument a powerful platform for high contrast imaging down to angular separations of the order of 1lambda/D and an ideal testbed for exploring coronagraphic techniques for ELTs. In this paper we report on the recent progress in regards to the development of the instrument, which includes the addition of a visible bench that makes use of the light at shorter wavelengths not currently utilized by SCExAO and closing the loop on the tip/tilt wavefront sensor. We will also discuss several exciting guest instruments which will expand the capabilities of SCExAO over the next few years; namely CHARIS which i...

  5. O INCENTIVO FISCAL EMPRESARIAL COMO FORMA DE PROTEÇÃO AO MEIO AMBIENTE

    OpenAIRE

    Patrícia Machado Iserhardt

    2013-01-01

    O presente artigo se refere ao incentivo fiscal empresarial como forma de proteção ao meio ambiente. A função extrafiscal dos tributos é de extrema importância ao meio ambiente, pois, assim, o Estado através da arrecadação de receitas tem a possibilidade de implementar ações que visem a proteção do meio ambiente. Portanto, o mecanismo hora estudado, vem mostrar que há possibilidade de inserir a classe empresarial na contemplação deste mecanismo de proteção. A classe empresarial pode participa...

  6. Ressecção de metástase hepática de sarcomas de partes moles Liver resection for metastatic soft tissue sarcomas

    Directory of Open Access Journals (Sweden)

    Rinaldo Gonçalves da Silva

    2006-12-01

    Full Text Available OBJETIVO: Avaliar os resultados do tratamento cirúrgico de pacientes portadores de metástases hepáticas de sarcomas de partes moles, com ênfase na identificação de fatores prognósticos e estudo de sobrevida. MÉTODO: Foi realizada análise retrospectiva de pacientes submetidos a ressecções hepáticas por sarcomas de partes moles metastáticos para fígado no Instituto Nacional de Câncer - MS entre 1992 e 2002. Fatores demográficos, características do tumor primário e dos tumores metastáticos, intervalo de surgimento de metástases, tipo de ressecção e resultados de sobrevida global e livre de doença, considerados a partir da operação para o tumor metastático foram considerados. Os dados obtidos foram analisados estatisticamente através dos softwares SPSS versão 8 e EpiInfo 2002.. RESULTADOS: O tumor primário era localizado no trato gastrintestinal em cinco pacientes, no retroperitônio em quatro e nos dois restantes no útero e no músculo deltóide. Leiomiossarcoma foi a linhagem histológica em 10 casos e dermatofibrossarcoma no caso restante, com grau de diferenciação tumoral G2 em seis casos e G3 em cinco. A extensão da ressecção hepática foi a segmentectomia em cinco pacientes, a lobectomia em quatro e as ressecções maiores em dois pacientes. Dois pacientes tiveram ressecções extra-hepáticas associadas. A ressecção foi completa em sete pacientes, persistindo doença residual macroscópica em quatro pacientes. Pela análise multivariada a sobrevida foi afetada pela radicalidade da ressecção, com 49 meses para as cirurgias completas e 15 meses para as incompletas (pBACKGROUND: The objective of this study was to evaluate the surgical treatment of patients with liver metastasis of soft tissue sarcomas, with emphasis on the identification of prognostic factors and survival. METHODS: This is a retrospective analysis of liver resections for metastatic soft tissue sarcomas performed at National Institute of

  7. Estimating surface CO2 fluxes from space-borne CO2 dry air mole fraction observations using an ensemble Kalman Filter

    Directory of Open Access Journals (Sweden)

    S. Dance

    2008-11-01

    Full Text Available We have developed an ensemble Kalman Filter (EnKF to estimate 8-day regional surface fluxes of CO2 from space-borne CO2 dry-air mole fraction observations (XCO2 and evaluate the approach using a series of synthetic experiments, in preparation for data from the NASA Orbiting Carbon Observatory (OCO. The 32-day duty cycle of OCO alternates every 16 days between nadir and glint measurements of backscattered solar radiation at short-wave infrared wavelengths. The EnKF uses an ensemble of states to represent the prior error covariance to estimate 8-day CO2 surface fluxes over 144 geographical regions. We use a 12×8-day lag window, recognising that XCO2 measurements include surface flux information from prior time windows. The observation operator that relates surface CO2 fluxes to atmospheric distributions of XCO2 includes: a the GEOS-Chem transport model that relates surface fluxes to global 3-D distributions of CO2 concentrations, which are sampled at the time and location of OCO measurements that are cloud-free and have aerosol optical depths 2 profiles to XCO2, accounting for differences between nadir and glint measurements, and the associated scene-dependent observation errors. We show that OCO XCO2 measurements significantly reduce the uncertainties of surface CO2 flux estimates. Glint measurements are generally better at constraining ocean CO2 flux estimates. Nadir XCO2 measurements over the terrestrial tropics are sparse throughout the year because of either clouds or smoke. Glint measurements provide the most effective constraint for estimating tropical terrestrial CO2 fluxes by accurately sampling fresh continental outflow over neighbouring oceans. We also present results from sensitivity experiments that investigate how flux estimates change with 1 bias and unbiased errors, 2 alternative duty cycles, 3 measurement density and correlations, 4 the spatial resolution of estimated flux estimates, and 5 reducing the length of the lag window

  8. Microhabitat types promote the genetic structure of a micro-endemic and critically endangered mole salamander (Ambystoma leorae of Central Mexico.

    Directory of Open Access Journals (Sweden)

    Armando Sunny

    Full Text Available The reduced immigration and emigration rates resulting from the lack of landscape connectivity of patches and the hospitality of the intervening matrix could favor the loss of alleles through genetic drift and an increased chance of inbreeding. In order for isolated populations to maintain sufficient levels of genetic diversity and adapt to environmental changes, one important conservation goal must be to preserve or reestablish connectivity among patches in a fragmented landscape. We studied the last known population of Ambystoma leorae, an endemic and critically threatened species. The aims of this study were: (1 to assess the demographic parameters of A. leorae and to distinguish and characterize the microhabitats in the river, (2 to determine the number of existing genetic groups or demes of A. leorae and to describe possible relationships between microhabitats types and demes, (3 to determine gene flow between demes, and (4 to search for geographic locations of genetic discontinuities that limit gene flow between demes. We found three types of microhabitats and three genetically differentiated subpopulations with a significant level of genetic structure. In addition, we found slight genetic barriers. Our results suggest that mole salamander's species are very sensitive to microhabitat features and relatively narrow obstacles in their path. The estimates of bidirectional gene flow are consistent with the pattern of a stepping stone model between demes, where migration occurs between adjacent demes, but there is low gene flow between distant demes. We can also conclude that there is a positive correlation between microhabitats and genetic structure in this population.

  9. Potencialidades e espaços ao empreendedorismo

    Directory of Open Access Journals (Sweden)

    Adriano Lago

    2008-01-01

    Full Text Available A criação de negócios é apontada como uma das causas da prosperidade de um local, região, estado ou de um país. É neste sentido que o empreendedorismo tem recebido destaque nos últimos anos, como promotor de novos negócios. Captar, descrever e analisar o fenômeno do empreendedorismo é, portanto, necessário para o desenho de ações de promoção do desenvolvimento. Assim, o presente estudo aborda o empreendedorismo na piscicultura, tomando como base três casos analisados: uma propriedade com rizipiscicultura, uma com piscicultura de ciclo completo inclusive com frigorífico, e outra onde a piscicultura desenvolve-se através de um pesque-pague, com vistas a proporcionar o turismo rural. Para fins de pesquisa, entrevistaram-se os proprietários de cada estabelecimento na busca dos dados necessários para a construção de uma abordagem consistente da temática proposta, ou seja, identificar a presença do empreendedorismo e suas características particulares em cada propriedade analisada. Verificou-se que determinadas características empreendedoras são comuns aos três casos analisados: habilidade para identificar oportunidades; busca de conhecimento de sua área de atuação; senso de organização; disposição para tomar decisões; capacidade de liderança; talento para empreender; otimismo e tino empresarial; ser estrategista, além do dinamismo. Portanto, foi possível observar que o perfil empreendedor dos proprietários de cada negócio tornou possível a transformação de idéias e problemas em oportunidades reais de negócio.Abstract The business opening is indicated as one of the prosperity causes of a country, state, region or local. It’s in this context that the entrepreneurship has received attention along the last years as new business promoter. This way, to study and promote development actions it’s necessary, firstly, to get, to describe and to analyze the entrepreneurship phenomenon by itself. So, this study

  10. Safety evaluation of pectin-derived acidic oligosaccharides (pAOS): Genotoxicity and sub-chronic studies

    NARCIS (Netherlands)

    Garthoff, J.A.; Heemskerk, S.; Hempenius, R.A.; Lina, B.A.R.; Krul, C.A.M.; Koeman, J.H.; Speijers, G.J.A.

    2010-01-01

    Pectin-derived acidic oligosaccharides (pAOS) are non-digestible carbohydrates to be used in infant formulae and medical nutrition. To support its safety, the genotoxic potential of pAOS was evaluated. pAOS was not mutagenic in the Ames test. Positive results were obtained in the chromosome aberrati

  11. Attitude toward contraception and abortion among Curaçao women. Ineffective contraception due to limited sexual education?

    NARCIS (Netherlands)

    Brink, M.J.; Boersma, A.A.; Meyboom-deJong, B; Bruijn, de J.G.M.

    2011-01-01

    Background In Curaçao is a high incidence of unintended pregnancies and induced abortions. Most of the induced abortions in Curaçao are on request of the woman and performed by general practitioners. In Curaçao, induced abortion is strictly prohibited, but since 1999 there has been a policy of conni

  12. Te Ao Kori as Expressive Movement in Aotearoa New Zealand Physical Education Teacher Education (PETE): A Narrative Account

    Science.gov (United States)

    Legge, Maureen

    2011-01-01

    A unique aspect of Aotearoa/New Zealand physical education is the inclusion of Maori culture in the form of te ao kori. Te ao kori translates to mean the world of movement and is represented by the interpretation of indigenous movement, games and pastimes. Participation in te ao kori means the sports-based normative frame of reference for physical…

  13. Ciberespaço cubano: uma forma de resistência ao poder e à censura

    Directory of Open Access Journals (Sweden)

    Lia Hecker Luz

    2011-01-01

    Full Text Available A entrada do corpo e da vida nos cálculos do poder corresponde ao que Foucault chamou de biopolítica. Entretanto, o próprio Foucault intuiu que aquilo mesmo que o poder investia – a vida – era o que doravante ancoraria a resistência a ele. Assim, ao poder sobre a vida deveria responder a potência da vida, capaz de operar uma resistência possível ao sequestro da vida pelo poder. Apoiando-nos no pensamento de Lévy, levantamos a hipótese, a partir da análise do blog Generación Y, de que a blogosfera cubana é uma expressão micropolítica de resistência ao poder, de biopotência da multidão.

  14. A Conversation with his Honour Chief Judge Michael Rozenes AO County Court of Victoria

    Directory of Open Access Journals (Sweden)

    Michael Rozenes

    2014-10-01

    Full Text Available VULJ Editors and invited students interviewed the Chief Judge of the County Court of Victoria, His Honour Michael Rozenes AO QC, on Tuesday 19 August 2014 at the College of Law & Justice, Victoria University.

  15. High specific activity N-Acetyl-3{sup H}-{alpha}-Aspartyl- L-Glutamic at micro mole scale; Sintesis de N-Acetil-3{sup H}- {alpha} -Aspartil-Glutamico a escala de Micromoles

    Energy Technology Data Exchange (ETDEWEB)

    Suarez, C.

    1984-07-01

    High specific activity N-Acetyl-3{sup H}- {alpha} -Aspartyl-I-Glutamic acid at micro mole scale in prepared acetylating L- {alpha} -Aspartyl-L-glutamic with 3{sup H}-acetic anhydride in re distilled toluene. The product le purified through cationic and anionic columns. The radiochemical purity as determined by thin-layer chromatography is greater then 99% at the time preparation. (Author) 5 refs.

  16. Hammering beneath the surface of Mars – Modeling and simulation of the impact-driven locomotion of the HP3-Mole by coupling enhanced multi-body dynamics and discrete element method

    OpenAIRE

    Lichtenheldt, Roy; Schäfer, Bernd; Krömer, Olaf

    2014-01-01

    As the formation of the rocky planets in our inner solar system has always been a major subject of scientific interest, NASA’s discovery mission InSight (Interior Seismic Investigations, Geodesy and Heat Transport) intends to gain further knowledge about the interior structure of Mars. In order to understand the processes that lead to planetary evolution, Mars’ seismic as well as thermal properties will be measured. DLR’s HP3-Mole (Heat Flow and Physical Properties Package), an innovative sel...

  17. Influence of Anion and Mole Ratio on the Coordination Behavior of an NO2S3-Macrocycle: The Formation of a Dumbbell-Shaped Macrocyclic Cadmium(II) Iodide Complex.

    Science.gov (United States)

    Lee, Hyeong-Hwan; Lee, Eunji; Ju, Huiyeong; Kim, Seulgi; Park, In-Hyeok; Lee, Shim Sung

    2016-03-01

    Anion and mole ratio dependent formations of cadmium(II) complexes with an NO2S3-macrocycle (L) incorporating a pyridine subunit are reported. When the cadmium(II) salts (1-10 equiv) with different halide ions (Br(-) or I(-)) were reacted with L, CdBr2 afforded a monomer complex, [Cd(L)Br]2[Cd2Br6]·CH2Cl2 (1), with three separated parts in the whole mole ratio range: two 1:1 stoichiometric complex cation parts and one Cd2Br6 cluster anion part. After separation of 1 by filtration, [Cd(L)Br]2[CdBr4]·CH2Cl2 (2) with similar composition was afforded, except the cluster was isolated from the filtrate. Unlike the CdBr2 complexation, CdI2 afforded the mole ratio dependent products (3-5). Below 2.5 equiv of CdI2, [Cd(L)I]2[CdI4]·CH2Cl2 (3) and [Cd(L)I]2[Cd2I6]·0.5CH2Cl2 (4) with different cadmium(II) iodide clusters were isolated as kinetic (3) and a thermodynamic (4) products. Notably, the use of 3 equiv or above amount of CdI2 gave a dumbbell-shaped complex, {[Cd(L)]2(μ-Cd4I12)} (5), in which two mononuclear macrocyclic complex units are linked by a (μ-Cd4I12)(4-) cluster. To monitor the mole ratio dependency as well as their reactivities, the systematic powder X-ray diffraction (PXRD) analysis has also been applied.

  18. Tunable diode laser absorption spectroscopy-based tomography system for on-line monitoring of two-dimensional distributions of temperature and H{sub 2}O mole fraction

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Lijun, E-mail: lijunxu@buaa.edu.cn; Liu, Chang; Jing, Wenyang; Cao, Zhang [School of Instrument Science and Opto-Electronic Engineering, Beihang University, Beijing 100191 (China); Ministry of Education’s Key Laboratory of Precision Opto-Mechatronics Technology, Beijing 100191 (China); Xue, Xin; Lin, Yuzhen [School of Energy and Power Engineering, Beihang University, Beijing 100191 (China)

    2016-01-15

    To monitor two-dimensional (2D) distributions of temperature and H{sub 2}O mole fraction, an on-line tomography system based on tunable diode laser absorption spectroscopy (TDLAS) was developed. To the best of the authors’ knowledge, this is the first report on a multi-view TDLAS-based system for simultaneous tomographic visualization of temperature and H{sub 2}O mole fraction in real time. The system consists of two distributed feedback (DFB) laser diodes, a tomographic sensor, electronic circuits, and a computer. The central frequencies of the two DFB laser diodes are at 7444.36 cm{sup −1} (1343.3 nm) and 7185.6 cm{sup −1} (1391.67 nm), respectively. The tomographic sensor is used to generate fan-beam illumination from five views and to produce 60 ray measurements. The electronic circuits not only provide stable temperature and precise current controlling signals for the laser diodes but also can accurately sample the transmitted laser intensities and extract integrated absorbances in real time. Finally, the integrated absorbances are transferred to the computer, in which the 2D distributions of temperature and H{sub 2}O mole fraction are reconstructed by using a modified Landweber algorithm. In the experiments, the TDLAS-based tomography system was validated by using asymmetric premixed flames with fixed and time-varying equivalent ratios, respectively. The results demonstrate that the system is able to reconstruct the profiles of the 2D distributions of temperature and H{sub 2}O mole fraction of the flame and effectively capture the dynamics of the combustion process, which exhibits good potential for flame monitoring and on-line combustion diagnosis.

  19. East Asian winter temperature variation associated with the combined effects of AO and WP pattern

    Science.gov (United States)

    Park, Hye-Jin; Ahn, Joong-Bae

    2016-04-01

    The combined effects of the Arctic Oscillation (AO) and Western Pacific (WP) teleconnection pattern on the East Asian winter monsoon (EAWM) over the last 56 years (1958/59-2013/2014) were investigated using NCEP/NCAR reanalysis data (Park and Ahn, 2015). The study results revealed that the effect of the AO on winter temperature in East Asia could be changed depending on the phases of the WP pattern in the North Pacific. The negative relationship between the EAWM and the AO increased when the AO and WP were in-phase with each other. Hence, when winter negative (positive) AO was accompanied by negative (positive) WP, negative (positive) temperature anomalies were dominant across the entire East Asia region. Conversely, when the AO and WP were of-of-phase, the winter temperature anomaly in East Asia did not show distinct changes. Furthermore, from the perspective of stationary planetary waves, the zonal wavenumber-2 patterns of sea level pressure and geopotential height at 500hPa circulation strengthened when the AO and WP were in-phase but were not significant for the out-of-phase condition. It explained the possible mechanism of the combined effects of the AO and WP on the circulation related to EAWM. Reference Park, H.-J., and J.-B. Ahn (2015) Combined effect of the Arctic Oscillation and the Western Pacific pattern on East Asia winter temperature, Clim. Dyn. DOI:10.1007/s00382-015-2763-2. Acknowledgements This work was funded by the Korea Meteorological Administration Research and Development Program under grant KMIPA2015-2081.

  20. Antecedents to the Perpetration of Domestic Violence in Curaçao

    OpenAIRE

    Wijk, van, C.; Bruijn, de, M.E.

    2015-01-01

    ABSTRACT Previous international studies have found collectivism and low gender empowerment to contribute to higher domestic violence perpetration by males, compared to females. Little is known about gender differences in domestic violence perpetration prevalence in collectivist countries with high gender empowerment, for example Curaçao. Curaçao demonstrates gender similarity in committing domestic violence, resembling Western countries: 25–33 % have committed psychological domestic violence,...

  1. Termination of Pregnancy in Curaçao: Need for Improvement of Sexual and Reproductive Healthcare

    OpenAIRE

    2012-01-01

    Background: In Curaçao Termination of Pregnancy (TOP) is still forbidden by law, although a policy of tolerance has been stipulated since 1999. This paper is about the prevalence of TOP and about its health complications. These data on TOP are officially unknown but are suspected to be rather high. Methods: One year registration of illegal performed termination of pregnancy cases by all general physicians (GPs) practicing TOP in Curaçao. The registration included patient characteristics accor...

  2. MagAO: Status and on-sky performance of the Magellan adaptive optics system

    CERN Document Server

    Morzinski, Katie M; Males, Jared R; Kopon, Derek; Hinz, Phil M; Esposito, Simone; Riccardi, Armando; Puglisi, Alfio; Pinna, Enrico; Briguglio, Runa; Xompero, Marco; Quirós-Pacheco, Fernando; Bailey, Vanessa; Follette, Katherine B; Rodigas, T J; Wu, Ya-Lin; Arcidiacono, Carmelo; Argomedo, Javier; Busoni, Lorenzo; Hare, Tyson; Uomoto, Alan; Weinberger, Alycia

    2014-01-01

    MagAO is the new adaptive optics system with visible-light and infrared science cameras, located on the 6.5-m Magellan "Clay" telescope at Las Campanas Observatory, Chile. The instrument locks on natural guide stars (NGS) from 0$^\\mathrm{th}$ to 16$^\\mathrm{th}$ $R$-band magnitude, measures turbulence with a modulating pyramid wavefront sensor binnable from 28x28 to 7x7 subapertures, and uses a 585-actuator adaptive secondary mirror (ASM) to provide flat wavefronts to the two science cameras. MagAO is a mutated clone of the similar AO systems at the Large Binocular Telescope (LBT) at Mt. Graham, Arizona. The high-level AO loop controls up to 378 modes and operates at frame rates up to 1000 Hz. The instrument has two science cameras: VisAO operating from 0.5-1 $\\mu$m and Clio2 operating from 1-5 $\\mu$m. MagAO was installed in 2012 and successfully completed two commissioning runs in 2012-2013. In April 2014 we had our first science run that was open to the general Magellan community. Observers from Arizona, Ca...

  3. Decolorization of the AO24 azo dye and reduction of toxicity and genotoxicity in trickling biofilters.

    Science.gov (United States)

    Garzóón-Zúñga, Marco A; Sandoval-Villasana, Ana M; Moeller-Chávez, Gabriela E

    2011-02-01

    Acid Orange 24 (AO24) dye was degraded in a trickling biofilter packed with peat and wood chips and inoculated with biomass from a petrochemical industry wastewater system. Different operating strategies were tested; in the first stage, two biofilters were operated independently--one non-aerated biofilter (passive) and the other with aeration-subsequently, the systems were operated serially, and effluent from the non-aerated biofilter was fed to the biofilter with aeration. This treatment train was used to test three different filtration velocities--0.141, 0.282, and 0.423 m/d. The results show that, when operating the systems with a dye charge of 0.035 kg AO24 m2/d and treating the effluent in a single step, good removal efficiencies of AO24 (95 and 89%), COD (63 and 53%), and acute toxicity (63 and 78%) were obtained in both biofilters (with and without air), although mutagenic and potentially carcinogenic intermediary compounds were not removed, because genotoxicity exhibits values higher than 2.0 units for the mutation rate. When using the non-aerated biofilter/aerated biofilter treatment train, it is possible to treat a dye charge 3 times greater (0.106 kg AO24 m2/d) and efficiently remove 98% AO24, 76% COD, 100% acute toxicity, and 100% genotoxicity, which indicates that, with this biological system, an advanced degree of biotransformation and mineralization of the azo dye AO24 is achieved.

  4. Parameterising E-ELT AO PSFs for detailed science simulations for HARMONI

    Science.gov (United States)

    Zieleniewski, Simon; Thatte, Niranjan

    2013-12-01

    With the first ELTs around the corner it is becoming ever more important to determine observational strategies and assess the prospective success of observing programs prior to making the observations. To this end, scientific simulations need to become more refined to understand the criteria required for a specific science case. We address the science simulations for HARMONI, an AO assisted first light integral field spectrograph (IFS) for the E-ELT. AO PSFs vary markedly as a function of wavelength and type of AO system used, so there is need to create detailed PSFs across all IFS wavelength channels for accurate simulations. Detailed AO simulations have shown that for LTAO on the E-ELT, Strehl ratios can vary from 0.5E-3 in V-band up to 0.5 in K-band. Using a single PSF for an entire datacube (especially with large instantaneous wavelength coverage) could introduce misleading features into simulated observations using HARMONI. We have developed a method to parameterize detailed PSFs using analytical models, which can then be interpolated as a function of wavelength. This allows us to create accurate, but computationally inexpensive, AO PSF datacubes for HARMONI simulations. This shall be developed to cover LTAO, SCAO and GLAO/no-AO PSFs for a range of observing parameters.

  5. Effects of Dexamethasone on glucocorticoid receptor expression in a human ovarian carcinoma cell line 3AO

    Institute of Scientific and Technical Information of China (English)

    徐明娟; 宋亮年; 王昭梅

    2003-01-01

    Objective To observe the effects of Dexamethasone (Dex), a synthetic glucocorticoid, on glucocorticoid receptor expression in the human ovarian carcinoma cell line 3AO. The molecular mechanism of glucocorticoid (GC) on 3AO cells was also studied.Methods The expression and regulation of the glucocorticoid receptor in 3AO cells was studied by utilizing radioligand binding assay and quantitative RT-PCR. Results High affinity and low capacity GR existed in 3AO cells, in addition, GR binding activity was down-regulated by Dex in a time-dependent manner, to a level about 28.34% of control following 24 hours treatment, with a concomitant decrease in GR mRNA. The induction of alkaline phosphatase (AKP) activity by Dex was reversed by RU486, a potent glucocorticoid antagonist.Conclusion In 3AO cells, functional GR which can be down-regulated by Dex at the protein and mRNA level, exists suggesting that the regulating effects of Dex on GR occur at least partially at the GR mRNA level, and that the cellular effects of Dex on 3AO cells might be mediated by GR.

  6. Fatores associados ao baixo peso ao nascimento entre adolescentes no Sudeste do Brasil Factors associated with low birth weight among adolescents in the Brazil Southeast region

    Directory of Open Access Journals (Sweden)

    Fernanda Garanhani Castro Surita

    2011-10-01

    Full Text Available OBJETIVOS: Conhecer a prevalência e alguns fatores associados ao baixo peso ao nascer entre gestantes adolescentes. MÉTODOS: Estudo de corte transversal, realizado entre outubro de 1994 a dezembro de 2009, com os partos ocorridos em uma maternidade de Campinas, utilizando informações coletadas em uma Ficha Obstétrica Informatizada. Foram selecionados os casos de partos entre adolescentes e, posteriormente, separados em dois grupos com e sem baixo peso ao nascer. Foram calculados o risco relativo e o intervalo de confiança (IC de 95% para as variáveis independentes (fatores de risco, e calculou-se o teste do Χ2 para comparação dos resultados perinatais. Assumiu-se nível de significância de 5%. RESULTADOS: No período ocorreram 24.000 partos no Centro de Atenção à Saúde da Mulher (CAISM, com 2.404 em 2.357 adolescentes (10,02%, sendo a frequência de baixo peso ao nascer de 15,1%. A gestação neste grupo foi recorrente em 294 (8,2%. A idade menor que 15 anos, anemia, tabagismo e hipertensão não se associaram ao baixo peso ao nascer. O antecedente de aborto e a associação com lúpus eritematoso sistêmico elevaram o risco de baixo peso ao nascer. A necessidade de cesariana e o Apgar menor que sete também foram mais prevalentes entre as adolescentes com baixo peso ao nascer, e 85% das adolescentes realizaram menos de seis consultas durante o pré-natal. CONCLUSÕES: A prevalência de baixo peso ao nascer é maior entre as adolescentes do que na população geral. Também chamou a atenção o grande número de adolescentes com menos de seis consultas durante o pré-natal. O antecedente de aborto e a presença de lúpus eritematoso sistêmico foram fatores de risco para ocorrência de baixo peso ao nascer em gestantes adolescentes.PURPOSES: To determine the rate of low birth weight and some of the risk factors associated with this event among adolescents. METHODS: A cross-sectional study conducted between October 1994 and

  7. Modelos para o planejamento centralizado da produçao e o transporte na cadeia de suprimento: uma revisao

    OpenAIRE

    Mula, Josefa; Peidro, David; Díaz-Madronero, Manuel; JORGE E. HERNÁNDEZ

    2011-01-01

    Este artigo apresenta uma revisao bibliográfica sobre os modelos de programaçao matematica para o planejamento centralizado da produçao e a transporte em uma cadeia de suprimento. O propósito desta revisao e identificar a pesquisa atual e futura neste campo e propor um marco de classificaçao baseado nos seguintes elementos: Estrutura da cadeia de suprimento, nivel de decisao, enfoque de modelagem, propósito, informaçao intercambiada e aplicaçao pratica. O objetivo do artigo e proporcionar um ...

  8. Instrumento mensurador de adesao para hipertensos: contribuicao da Teoria da Resposta ao Item

    Directory of Open Access Journals (Sweden)

    Malvina Thais Pacheco Rodrigues

    2013-06-01

    Full Text Available OBJETIVO: Analisar instrumento de medição da adesão ao tratamento da hipertensão por meio da "Teoria da Resposta ao Item". MÉTODOS: Estudo analítico com 406 hipertensos com complicações associadas, atendidos na atenção básica em Fortaleza, CE, 2011, pela "Teoria da Resposta ao Item". As etapas de execução foram: teste de dimensionalidade, calibração dos itens; tratamento dos dados e construção da escala, analisadas com base no modelo de resposta gradual. Estudo da dimensionalidade do instrumento foi feito pela análise da matriz de correlação policórica e análise fatorial de informação completa. Utilizou-se o software Multilog para calibração dos itens e estimação dos escores. RESULTADOS: Os itens referentes ao tratamento medicamentoso foram os mais diretamente relacionados à adesão, enquanto aqueles referentes ao tratamento não medicamentoso precisam ser reformulados, pois possuíram menor quantidade de informação psicométrica e baixa discriminação. A independência dos itens, o reduzido número de níveis da escala e as baixas variâncias explicadas no ajuste dos modelos mostraram as principais fragilidades do instrumento analisado. A "Teoria da Resposta ao Item" mostrou-se relevante para análise, pois avaliou o respondente quanto à adesão ao tratamento da hipertensão, ao nível de dificuldade dos itens e à sua capacidade de discriminação entre indivíduos com diferentes níveis de adesão, o que gerou maior quantidade de informação. CONCLUSÕES: O instrumento analisado é limitado para medir a adesão ao tratamento da hipertensão, mediante análise pela "Teoria da Resposta ao Item", e necessita de ajustes. A adequada formulação dos itens é importante para medir precisamente o traço latente desejado.

  9. Estimating surface CO2 fluxes from space-borne CO2 dry air mole fraction observations using an ensemble Kalman Filter

    Directory of Open Access Journals (Sweden)

    S. Dance

    2009-04-01

    Full Text Available We have developed an ensemble Kalman Filter (EnKF to estimate 8-day regional surface fluxes of CO2 from space-borne CO2 dry-air mole fraction observations (XCO2 and evaluate the approach using a series of synthetic experiments, in preparation for data from the NASA Orbiting Carbon Observatory (OCO. The 32-day duty cycle of OCO alternates every 16 days between nadir and glint measurements of backscattered solar radiation at short-wave infrared wavelengths. The EnKF uses an ensemble of states to represent the error covariances to estimate 8-day CO2 surface fluxes over 144 geographical regions. We use a 12×8-day lag window, recognising that XCO2 measurements include surface flux information from prior time windows. The observation operator that relates surface CO2 fluxes to atmospheric distributions of XCO2 includes: a the GEOS-Chem transport model that relates surface fluxes to global 3-D distributions of CO2 concentrations, which are sampled at the time and location of OCO measurements that are cloud-free and have aerosol optical depths 2 profiles to XCO2, accounting for differences between nadir and glint measurements, and the associated scene-dependent observation errors. We show that OCO XCO2 measurements significantly reduce the uncertainties of surface CO2 flux estimates. Glint measurements are generally better at constraining ocean CO2 flux estimates. Nadir XCO2 measurements over the terrestrial tropics are sparse throughout the year because of either clouds or smoke. Glint measurements provide the most effective constraint for estimating tropical terrestrial CO2 fluxes by accurately sampling fresh continental outflow over neighbouring oceans. We also present results from sensitivity experiments that investigate how flux estimates change with 1 bias and unbiased errors, 2 alternative duty cycles, 3 measurement density and correlations, 4 the spatial resolution of estimated flux estimates, and 5 reducing the length of the lag window and the

  10. Surface and bulk modifications of 1.5 mole % Sr/La{sub 2}O{sub 3} catalyst with different Co, Ni, and Cu amounts

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez Cortes, Sergio; Fontal, Bernardo [Universidad de los Andes, Merida (Venezuela); Moronta, Delfin [Universidad Central de Venezuela, Caracas (Venezuela)

    2001-08-01

    The effects of Co, Ni and Cu oxide content on the surface and bulk of the 1.5 mole % Sr/La{sub 2}O{sub 3} catalysts were studied. Series of M/Sr-La catalysts (MCo, Ni, Cu) were prepared by successive immersion impregnation. The solids were characterized by X-ray diffraction (XRD), infrared spectroscopy (FTIR), temperature-programmed reduction (TPR), electron paramagnetic resonance (EPR), specific surface area measurements (BET) and thermogravimetric analysis (TGA). The Sr/La{sub 2}O{sub 3} modified with different Co, Ni, and Cu loading shows a strong metal oxide interaction with La{sub 2}O{sub 3}. This probably begin over anionic vacancies or structure defects favoring LaSrMO{sub x} solid solution formation with island-like structures according to a Volmer-Weber growth. It is proposed that the growth mode of La-Co, La-Ni and La-Cu stoichiometric phases occur from solid solutions. The formation of only a La-M single phase, probably non-stoichiometric, increases the material porosity while different phases favor the agglomeration or sintering of the particles. [Spanish] En este trabajo se estudia el efecto de la cantidad de cobalto, niquel y cobre sobre las estructuras superficial y masica del sistema 1.5% molar Sr/La{sub 2}O{sub 3}. Los catalizadores M/Sr-La (M = Co, Ni, Cu) fueron preparados por el metodo de impregnacion con exceso de solucion. Los solidos se caracterizaron por difraccion de rayos-X, espectroscopia infrarroja con transformada de Fourier, reduccion a temperatura programada, resonancia paramagnetica del electron, medidas del area superficial especifica por el metodo de BET y analisis termogravimetrico. El catalizador Sr/La{sub 2}O{sub 3} modificado con diferentes cantidades de Co, Ni y Cu muestra una interaccion fuerte con el oxido del metal de transicion, probablemente sobre las vacancias anionicas o defectos estructurales que favorecen la formacion de la solucion solida LaSrMox en forma de isla, segun el mecanismo de crecimiento de fase de Volmer

  11. Soft tissue Rosai-Dorfman disease of the posterior mediastinum Doença de Rosai-Dorfman de partes moles no mediastino posterior

    Directory of Open Access Journals (Sweden)

    Antônio Luiz Penna Costa

    2009-07-01

    Full Text Available Rosai-Dorfman disease (RDD consists of sinus histiocytosis with massive lymphadenopathy. Extranodal involvement occurs in up to 43% of cases. However, isolated soft tissue RDD is rare. Isolated mediastinal RDD is exceedingly rare, and there have been only three previous reports. Involvement of the posterior mediastinum in RDD has been reported only in the context of disseminated RDD. Here, we report the case of a 49-year-old female patient with a two-year history of cervical pain and lymphadenomegaly, which resolved spontaneously. A CT scan revealed a left paravertebral mass with a diameter of 6 cm. The patient was submitted to surgical excision of the mass. Microscopic examination and immunophenotyping of the surgical specimen led to a diagnosis of RDD. During a 12-month follow-up period, the patient complained of mild cough and chest pain. Periodic imaging tests showed no sign of recurrence, and no postoperative cervical lymphadenomegaly was detected.A doença de Rosai-Dorfman (DRD consiste em histiocitose sinusal com linfadenopatia maciça. O envolvimento extranodal ocorre em até 43% dos casos. Entretanto, a DRD de partes moles de forma isolada é rara. A forma isolada de DRD mediastinal é muito rara, com apenas três relatos prévios. O envolvimento do mediastino posterior só foi descrito no contexto da DRD disseminada. Relatamos o caso de uma paciente de 49 anos de idade com história de dor e linfadenomegalia cervical há dois anos, com resolução espontânea. A TC revelou uma massa paravertebral à esquerda medindo 6 cm de diâmetro. A paciente foi submetida à ressecção cirúrgica da massa. O exame microscópico e estudo do imunofenótipo da peça cirúrgica definiram o diagnóstico de DRD. A paciente foi acompanhada por 12 meses, queixando-se de tosse discreta e dor torácica. O acompanhamento por imagem não detectou recorrência, e nenhuma linfadenomegalia cervical foi observada após a cirurgia.

  12. Obstrução nasal total: estudo morfofuncional de um caso de sinéquia de palato mole e paredes faríngeas pós blastomicose Total nasal obstruction: a morphofunctional case study of post blastomicose palato and pharynx's lesion

    Directory of Open Access Journals (Sweden)

    Camila Queiroz de Moraes Silveira Di Ninno

    2012-10-01

    Full Text Available TEMA: identificar as alterações morfofuncionais decorrentes de quinze anos de obstrução nasal total em um caso de sinéquia de palato mole e paredes faríngeas pós blastomicose. PROCEDIMENTOS: o trabalho foi baseado no estudo de caso de um adulto do gênero feminino, de 26 anos de idade, que chegou a um centro especializado em deformidades craniofaciais, com a queixa de não conseguir respirar pelo nariz. Sua dificuldade respiratória é decorrente de uma aderência total do palato mole com as paredes faríngeas, como sequela da blastomicose que teve no palato aos 11 anos de idade. RESULTADOS: na entrevista, a paciente relatou queixa de cefaléia, halitose, pouco rendimento físico, sonolência diurna e sono agitado durante a noite. Referiu também anosmia, mastigação lenta e engasgos frequentes. Durante a avaliação, observou-se respiração exclusivamente oral do tipo superior, mastigação bilateral alternada e lenta, deglutição adaptada e ressonância hiponasal de grau grave. Observou-se ainda face longa, perfil convexo, mandíbula retruída e olheiras. Os lábios da paciente encontravam-se entreabertos e ressecados, sendo o superior fino e o inferior evertido e avolumado e o palato duro apresenta-se atrésico, estreito e profundo. CONCLUSÃO: as características da paciente em questão são compatíveis com a Síndrome do Respirador Oral e pode-se supor que sejam consequências morfofuncionais de uma obstrução nasal total.BACKGROUND: to identify the consequences that arising from fifteen years of total nasal obstruction in a case of post blastomicose palato and pharynx's lesion. PROCEDURES: this article was based on a case report of a 26-years-old female subject, who came to a specialized center on craniofacial deformities, complaining about her mouth breathing. Her respiratory difficulty stems from a total tack of palate and pharynx, as a blastomicose sequel that she had when 11-year-old. RESULTS: during the interview, the

  13. Photometric Properties for Selected Algol-type Binaries. II. AO Serpentis and V338 Herculis

    Science.gov (United States)

    Yang, Y.-G.; Hu, S.-M.; Guo, D.-F.; Wei, J.-Y.; Dai, H.-F.

    2010-04-01

    We present the first multiband photometry for the semidetached eclipsing binary AO Serpentis, observed on seven nights between 2009 April and July at the Weihai Observatory of Shandong University. By using the 2003 version of the Wilson-Devinney code, the photometric solutions of AO Ser and a similar object V338 Her were (re)deduced. The spectral types and orbital periods are A2 and P = 0.8793 days for AO Ser, F1V and P = 1.3057 days for V338 Her. The results reveal that two binaries are low mass ratio systems, whose secondary components fill their Roche lobes. The fill-out factors of the primary components are f = 58.6% for AO Ser and f = 54.2% for V338 Her, respectively. From the O - C curves of AO Ser and V338 Her, it is discovered that secular period changes with cyclic variations exist. The periods and semiamplitudes are 17.32(±0.01) yr and 0.0051(±0.0001) days for AO Ser, 29.07(±0.04) yr and 0.0116(±0.0015) days for V338 Her, respectively. This kind of cyclic oscillation may be attributed to either the light-time effect via an assumed third body or perhaps cyclic magnetic activity on the secondary component. For AO Ser, the long-term period decreases at a rate of dP/dt = -5.35(±0.03) × 10-7 days yr-1, which may be caused by mass and angular momentum loss from the system. Considering the period decreasing, the fill-out factor of the primary for AO Ser will increase and it will finally fill its Roche lobe. Meanwhile, the secular period increase rate for V338 Her is dP/dt = +1.44(±0.24) × 10-7 days yr-1, indicating that mass transfers from the less massive component to the more massive component. This will also cause the fill-out factor of the primary to increase. When the primaries fill their Roche lobes, AO Ser and V338 Her may evolve into contact stars, as predicted by the theory of thermal relaxation oscillations.

  14. Morfologia e Crescimento dos 6 aos 10 anos de idade em Viana do Castelo, Portugal

    Directory of Open Access Journals (Sweden)

    Luis Paulo Rodrigues

    2008-09-01

    Full Text Available Ao longo de quatro anos, o Estudo Morfofuncional da Criança Vianense observou 1911 crianças entre os 6e os 10 anos de idade, resultando em 4064 observações individuais(2054 de raparigas, 2006 de rapazes.Os resultados encontrados nos indicadores morfológicos simples(altura, peso, pregas adiposas, diâmetros ósseos e perímetros muscularese no somatótipo, são descritos normativamente (valores percentílicose comparados com outros estudos nacionais e internacionais. As crianças vianenses demonstraram possuir uma estatura média ligeiramente superior às reportadas nos estudos portugueses e um ritmo de crescimento diferente das norte-americanas; peso semelhante ao das congéneres nacionais mas inferior ao das EUA; valores de pregas adiposas geralmente inferiores aos encontrados em Portugal e EUA; perímetros musculares e diâmetros ósseos semelhantes aos seus pares portugueses; e uma tendência para o aumento, com a idade, do ectomorfismo nos rapazes e do endomorfismo em ambos os sexos. Este panorama parece indicar que as crianças vianenses apresentam características de aptidão morfologia que estão longe de espelhar as preocupações internacionais nesta matéria.

  15. Significant relationship between spring AO and the summer rainfall along the Yangtze River

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The influence of spring AO on the summer rainfall along the Yangtze River is investigated. The long-term rainfall observations are filtered to remove the low-frequency variations longer than 10 years. The inter-annual components show a high correlation to AO in the last hundred years. The strongest correlation appears for May AO and summer rainfall with a value of ?0.39, significant above the 99% confidence level. Associated with one standard deviation stronger May AO index, the rainfall over the Yangtze River to the southern Japan decreases by about 3%-9%, while, at the same time increases by about 3%-6% in the northern China and far-eastern Russia. The coherent changes in rainfall are significantly related to the East Asian summer jet stream in the upper troposphere. When there is stronger AO in spring, the jet stream tends to move polarward in summer, and leads the rainfall-belt to move northward too. That gives rise to a drier condition in the Yangtze River valley, wetter anomalies in northern China. This signal would be helpful for the summer rainfall prediction in China.

  16. Doença periodontal materna como fator associado ao baixo peso ao nascer Maternal periodontal disease as a factor associated with low birth weight

    OpenAIRE

    Simone Seixas da Cruz; Maria da Conceição N. Costa; Isaac Suzart Gomes Filho; Maria Isabel P. Vianna; Carlos Teles Santos

    2005-01-01

    OBJETIVO: Estudos recentes têm apresentado evidências de que a doença periodontal em gestantes pode ser um dos determinantes do baixo peso ao nascer. Realizou-se estudo para verificar a existência de associação entre doença periodontal materna e baixo peso ao nascer. MÉTODOS: Estudo do tipo caso-controle com 302 mulheres, sendo 102 mães de nascidos vivos de baixo peso (grupo caso) e 200 mães de nascidos vivos com peso normal (grupo controle). A existência de associação entre doença periodonta...

  17. Aspectos computacionais da implementaçao da formulaçao diferencial aplicada à análise reológica de barragens de concreto

    OpenAIRE

    Longo, Henrique I.; Fairbairn, Eduardo M.; Pereira, Geraldo L.

    1991-01-01

    Neste artigo sáo apresentadas as formulaçóes integral e diferencial para a modelizacão matemática do problema reológico do concreto, assim como a correspondencia entre as duas formulaçoes. Sáo então apresentados exemplos numéricos visando uma comparacáo da eficiencia computacional de algoritmos baseados nos dois tipos de modelizaçao. Peer Reviewed

  18. Up-regulated expression of AOS-LOXa and increased eicosanoid synthesis in response to coral wounding.

    Directory of Open Access Journals (Sweden)

    Helike Lõhelaid

    Full Text Available In octocorals, a catalase-like allene oxide synthase (AOS and an 8R-lipoxygenase (LOX gene are fused together encoding for a single AOS-LOX fusion protein. Although the AOS-LOX pathway is central to the arachidonate metabolism in corals, its biological function in coral homeostasis is unclear. Using an acute incision wound model in the soft coral Capnella imbricata, we here test whether LOX pathway, similar to its role in plants, can contribute to the coral damage response and regeneration. Analysis of metabolites formed from exogenous arachidonate before and after fixed time intervals following wounding indicated a significant increase in AOS-LOX activity in response to mechanical injury. Two AOS-LOX isoforms, AOS-LOXa and AOS-LOXb, were cloned and expressed in bacterial expression system as active fusion proteins. Transcription levels of corresponding genes were measured in normal and stressed coral by qPCR. After wounding, AOS-LOXa was markedly up-regulated in both, the tissue adjacent to the incision and distal parts of a coral colony (with the maximum reached at 1 h and 6 h post wounding, respectively, while AOS-LOXb was stable. According to mRNA expression analysis, combined with detection of eicosanoid product formation for the first time, the AOS-LOX was identified as an early stress response gene which is induced by mechanical injury in coral.

  19. O Ocaso da Utopia Telecomunicacional: regular para quem no tocante ao Direito Fundamental à Privacidade?

    Directory of Open Access Journals (Sweden)

    Conselho Editorial

    2014-05-01

    Full Text Available O presente estudo figura como introdução à Revista de Direito, Estado e Telecomunicações do Grupo de Estudos em Direito das Telecomunicações da Universidade de Brasília, abordando sinteticamente a estrutura, conteúdo e política editorial da revista. Em acréscimo, o texto analisa os principais acontecimentos do setor no Brasil, bem como normas e julgados relativos ao ano de 2013, para registro das principais discussões político-jurídicas do setor de telecomunicações brasileiro referentes ao ano anterior ao da publicação.

  20. A Arqueologia do cuidado: da prática ao discurso

    Directory of Open Access Journals (Sweden)

    Sidi Askofare

    2006-06-01

    Full Text Available A noção de cuidado, assimilada há muito tempo ao tratamento e, então, ao conceito de terapêutica, retorna, logo depois, nos estudos, pesquisas e reflexões nas ciências humanas. Mas, daí em diante, está emancipado de suas aderências e conotações médicas por serem demasiadamente redutoras. O presente artigo propõe uma arqueologia (no sentido foucaultiano do cuidado &– de suas origens animais às suas formas culturalmente e historicamente definidas &– e põe em evidência a subversão que produz no campo do cuidado &– das práticas aos discursos &– a emergência e a dominação do discurso da ciência.

  1. Vivências e sentimentos de profissionais de enfermagem nos cuidados ao paciente sem vida

    Directory of Open Access Journals (Sweden)

    Taíse Kuhn

    2011-12-01

    Full Text Available Este estudo teve como objetivo conhecer as vivências e sentimentos de dez profissionais da Enfermagem em relação ao paciente sem vida, em um hospital privado da região metropolitana de Porto Alegre-RS. Utilizou-se abordagem qualitativa, descritiva, exploratória, com dados coletados em julho de 2009, por meio de entrevista, com questionário semiestruturado. Os resultados foram agrupados nas categorias: sentimentos em relação à morte do paciente, reações à morte e preparo do corpo. Concluiu-se que as vivências mais marcantes foram aquelas relacionadas ao primeiro contato com a morte, à presença de vínculos emocionais com pacientes e familiares, e à idade dos pacientes no momento do óbito, sendo estes dois últimos considerados elementos dificultadores dos cuidados oferecidos ao paciente sem vida.

  2. A utilizaçao de módulos de ensino como metodologia para a mudança de conceito e atitudes de alunos do curso de habilitaçao ao magistério com relaçao a Ciencias e ao seu ensino

    OpenAIRE

    Barra, Vilma Marcassa

    1982-01-01

    Resumo: Inúmeras pesquisas já foram realizadas com a finalidade de avaliar os resultados da utilização de módulos de ensino na comunicação de informações teóricas. Este estudo, porem, não pretendeu avaliar tais resultados, mas sim verificar se uma determinada metodologia do ensino de Ciências pode ser proposta através de módulos de ensino e apreendida dessa forma pelas alunas do curso de Habilitação ao Magistério, em nível de 29 graus. A metodologia aqui tratada tem como pontos básicos: o uma...

  3. Characterization of phosphorus removal bacteria in (AO)2 SBR system by using different electron acceptors

    Institute of Scientific and Technical Information of China (English)

    JIANG Yi-feng; WANG Lin; YU Ying; WANG Bao-zhen; LIU Shuo; SHEN Zheng

    2007-01-01

    Characteristics of phosphorus removal bacteria were investigated by using three different types of electron acceptors, as well as the positive role of nitrite in phosphorus removal process. An (AO)2 SBR (anaerobic-aerobic-anoxic-aerobic sequencing batch reactor) was thereby employed to enrich denitrifying phosphorus removal bacteria for simultaneously removing phosphorus and nitrogen via anoxic phosphorus uptake. Ammonium oxidation was controlled at the first phase of the nitrification process. Nitrite-inhibition batch tests illustrated that nitrite was not an inhibitor to phosphorus uptake process, but served as an alternative electron acceptor to nitrate and oxygen if the concentration was under the inhibition level of 40mg NO2 - N · L- 1. It implied that in addition to the two well-accepted groups of phosphorus removal bacterium ( one can only utilize oxygen as electron acceptor, P1, while the other can use both oxygen and nitrate as electron acceptor, P2 ), a new group of phosphorus removal bacterium P3, which could use oxygen, nitrate and nitrite as electron acceptor to take up phosphorus were identified in the test system. To understand (AO)2 SBR sludge better, the relative population of the different bacteria in this system, plus another A/O SBR sludge (seed sludge) were respectively estimated by the phosphorus uptake batch tests with either oxygen or nitrate or nitrite as electron acceptor. The results demonstrated that phosphorus removal capability of (AO)2 SBR sludge had a little degradation after A/O sludge was cultivated in the (AO)2 mode over a long period of time. However, denitrifying phosphorus removal bacteria ( P2 and P3 ) was significantly enriched showed by the relative population of the three types of bacteria,which implied that energy for aeration and COD consumption could be reduced in theory.

  4. Genes regulated by AoXlnR, the xylanolytic and cellulolytic transcriptional regulator, in Aspergillus oryzae.

    Science.gov (United States)

    Noguchi, Yuji; Sano, Motoaki; Kanamaru, Kyoko; Ko, Taro; Takeuchi, Michio; Kato, Masashi; Kobayashi, Tetsuo

    2009-11-01

    XlnR is a Zn(II)2Cys6 transcriptional activator of xylanolytic and cellulolytic genes in Aspergillus. Overexpression of the aoxlnR gene in Aspergillus oryzae (A. oryzae xlnR gene) resulted in elevated xylanolytic and cellulolytic activities in the culture supernatant, in which nearly 40 secreted proteins were detected by two-dimensional electrophoresis. DNA microarray analysis to identify the transcriptional targets of AoXlnR led to the identification of 75 genes that showed more than fivefold increase in their expression in the AoXlnR overproducer than in the disruptant. Of these, 32 genes were predicted to encode a glycoside hydrolase, highlighting the biotechnological importance of AoXlnR in biomass degradation. The 75 genes included the genes previously identified as AoXlnR targets (xynF1, xynF3, xynG2, xylA, celA, celB, celC, and celD). Thirty-six genes were predicted to be extracellular, which was consistent with the number of proteins secreted, and 61 genes possessed putative XlnR-binding sites (5'-GGCTAA-3', 5'-GGCTAG-3', and 5'-GGCTGA-3') in their promoter regions. Functional annotation of the genes revealed that AoXlnR regulated the expression of hydrolytic genes for degradation of beta-1,4-xylan, arabinoxylan, cellulose, and xyloglucan and of catabolic genes for the conversion of D-xylose to xylulose-5-phosphate. In addition, genes encoding glucose-6-phosphate 1-dehydrogenase and L-arabinitol-4- dehydrogenase involved in D-glucose and L-arabinose catabolism also appeared to be targets of AoXlnR.

  5. Obtenção de plantas de feijão-caupi resistentes ao Cowpea severe mosaic virus e ao Cowpea aphid-borne mosaic virus

    Directory of Open Access Journals (Sweden)

    Gislanne Brito Barros

    2013-06-01

    Full Text Available Dentre os vírus que infectam o feijão-caupi (Vigna unguiculata L. Walp. destacam-se, respectivamente, pela severidade e ampla ocorrência o Cowpea severe mosaic virus (CPSMV e o Cowpea aphid-borne mosaic virus (CABMV. Portanto, objetivaram-se, no presente trabalho, obter e avaliar plantas de feijão-caupi com resistência ao CPSMV e ao CABMV, visando ao desenvolvimento de cultivares essencialmente derivadas e novas cultivares. Realizaram-se oito cruzamentos seguidos de retrocruzamentos, utilizando a linhagem TE 97-309G-9 e a cultivar Patativa como genitores resistentes, e as cultivares BR3-Tracuateua, BRS-Urubuquara, BRS-Novaera, BRS-Guariba e Pretinho como genitores suscetíveis. As gerações F2 e F2RC1 foram desafiadas quanto à resistência por meio de inoculação mecânica com isolados do CPSMV e do CABMV. Nas gerações F2RC1, além da resistência foram avaliados os caracteres: número de dias para o início da floração, comprimento das vagens, número de grãos. vagem-1, peso de cem grãos e produção de grãos.planta-1. Todos os indivíduos F2 e F2RC1 foram analisados pelo teste χ² e se ajustaram à frequência esperada de 15 plantas suscetíveis 1 planta resistente a ambos os vírus. As médias das plantas F2RC1 resistentes, de cada retrocruzamento, foram comparadas com a média do seu respectivo genitor recorrente pelo teste 't' e as médias dos retrocruzamentos foram comparadas pelo teste de Scott-Knott. Foi detectada variabilidade genética entre os retrocruzamentos para todos os caracteres. Todos os retrocruzamentos foram considerados promissores para produção de cultivares essencialmente derivadas resistentes ao CPSMV e ao CABMV e as plantas selecionadas possuem características que possibilitam a seleção de linhagens com grãos de bom padrão comercial e altamente produtivas.

  6. Clinical analysis of high-risk factors on malignant transformation of hydatidiform mole%高危因素对葡萄胎后恶变的影响临床分析

    Institute of Scientific and Technical Information of China (English)

    梁哨雅

    2014-01-01

    目的:分析有恶变高危因素的葡萄胎患者的临床特点,为提高妊娠滋养细胞肿瘤(GTN)的诊治手段提供借鉴。方法回顾性分析该院妇产科2007年1月至2013年12月162例在行清宫术后病理检查诊断为葡萄胎患者的临床资料,观察GTN的临床表现、治疗效果等,比较有高危因素与无高危因素葡萄胎后GTN患者的临床特点。结果162例葡萄胎患者中,有46例恶变,其中有高危因素患者36例,无高危因素患者10例。比较两类患者恶变率、临床表现及治疗后效果,早期葡萄胎合并高危因素患者恶变率及临床表现与无合并高危因素患者比较,差异均有统计学意义(P<0.05);葡萄胎后GTN患者治疗效果比较,差异无统计学意义(P>0.05)。结论葡萄胎恶变率与患者发病年龄、子宫大小、卵巢黄素囊肿等高危因素有关。因此,对患者高危因素进行正确评估,对临床早期预测葡萄胎恶变及给予预防性化疗有一定指导意义,也有助于诊治GTN和提高临床疗效。%Objective To analyze the clinical features of hydatidiform mole patients with high-risk factors,in order to provide reference for improving the diagnosis of the gestational trophoblastic tumor (GTN). Methods A retrospective analysis was conducted on clinical data of 162 hydatidiform mole patients ,who were diagnosed after uterine curettage by pathological ex-amination in the Obstetrics Department of the hospital from January 2007 to December 2013. To observe the clinical manifesta-tions of GTN,therapeutic effect and so on,and compare the clinical features of hydatidiform mole patients with and without high-risk factors. Results Amon the 162 patients with hydatidiform mole,46 cases had malignant transformation,including 36 cases with high-risk factors and 10 cases without high-risk factors. The malignant transformation rate,clinical manifestation and thera-peutic effects between the two

  7. Instrumentos relacionados ao diabetes mellitus adaptados e validados para a cultura brasileira

    OpenAIRE

    Raquel Curcio; Maria Helena Melo Lima; Neusa Maria Costa Alexandre

    2011-01-01

    Trata-se de um estudo de revisão integrativa, cujo objetivo foi buscar evidências disponíveis na literatura sobre os instrumentos e escalas relacionados ao diabetes mellitus adaptados e validados para a cultura brasileira. Após busca nas bases eletrônicas BDENF, SciELO, LILACS, foram incluídos sete instrumentos que atenderam aos critérios de inclusão: Diabetes Mellitus Knowledge (DKN-A); Diabetes Mellitus Attitude (ATT-19); Diabetes Quality of Life Measure (DQOL-Brasil); Diabetes Quality of L...

  8. Ressalto no canto posteromedial do joelho relacionado ao músculo sartório

    Directory of Open Access Journals (Sweden)

    Marcello Henrique Nogueira-Barbosa

    2011-06-01

    Full Text Available As causas da síndrome de ressalto no joelho relatadas com maior frequência são relacionadas a anormalidades meniscais, ao tendão do músculo bíceps femoral e aos tendões grácil e semitendíneo. Neste trabalho é descrito um caso de ressalto no canto posteromedial relacionado à junção miotendínea do músculo sartório em um paciente do sexo masculino, de 58 anos de idade, com hiperextensão do joelho.

  9. Fatores influentes na aderência ao tratamento em pacientes com risco cardiovascular

    OpenAIRE

    Rodríguez Acelas, Alba Luz; GÓMEZ OCHOA, ANA MARITZA

    2010-01-01

    Objetivo: descrever e analisar os fatores que influem na aderência ao tratamento farmacológico e não farmacológico em pacientes com risco de doença cardiovascular na Fundação Cardiovascular da Colômbia. Metodologia: estudo descritivo – metodológico realizado com 172 pacientes hospitalizados e de consulta ambulatória. O instrumento aplicado foi desenhado por Bonilla (8) e é útil para avaliar a aderência aos tratamentos farmacológicos e não farmacológicos em pacientes com fatores de risco de...

  10. O panorama das Drogas no México: da margem da sociedade ao centro da cultura

    OpenAIRE

    Diana Palaversich

    2013-01-01

    O artigo destaca o percurso das manifestações culturais ligadas ao tráfico de drogas no México, de um lugar marginal, de subcultura, na sociedade mexicana das décadas de 1970 e 1980, expressas principalmente através dos narcocorridos e do narcocine, para um lugar no mainstream cultural mexicano, desde o início do século 21, com destaque especial para a narcoliteratura. O aumento da violência, provocado pela guerra ao narcotráfico, produz uma proliferação da temática nos meios de comunicação e...

  11. Aplicação de apoio ao agendamento cirúrgico

    OpenAIRE

    Mandzyuk, Ivanna

    2014-01-01

    Mestrado em Decisão Económica e Empresarial Um dos problemas que surge dentro do bloco operatório é o agendamento de cirurgias eletivas, ou seja, as cirurgias cuja realização tenha data previamente marcada. Na maioria dos hospitais portugueses, esta continua ainda a ser uma tarefa manual, difícil, e que exige muito tempo ao planeador cirúrgico. Este trabalho desenvolve uma ferramenta informática que permite apoiar o planeador cirúrgico, nas suas decisões, ao nível do agendamento dos cas...

  12. The Ashkenazi Jews of Curaçao, a trading minority

    Directory of Open Access Journals (Sweden)

    Eva Abraham-Van der Mark

    2000-07-01

    Full Text Available First describes the early Sephardi presence in Curaçao, the arrival of the Ashkenazi in the 20th c., and the relations between these 2 groups. Author goes on to discuss the Ashkenazis' economic success and the exodus of the 1980s. She asks whether the success and the exodus can be attributed to the characteristics of the group itself or whether conditions and developments in Curaçao account for economic fortune and the departure of the Ashkenazi.

  13. Estímulo ao desenvolvimento infantil: produção do conhecimento em enfermagem

    OpenAIRE

    Bruna Cristine Peres Falbo; Raquel Dully Andrade; Maria Cândida de Carvalho Furtado; Débora Falleiros de Mello

    2012-01-01

    Este estudo teve como objetivo identificar as ações de enfermagem para estímulo ao desenvolvimento infantil, em periódicos nacionais e internacionais, no período de 2000 a 2009. Revisão integrativa da literatura, nas bases de dados Medline e Lilacs, com análise de quinze artigos. Os resultados apontam o lúdico como essencial ao desenvolvimento infantil, devendo ser explorado pela enfermagem por meio da arte, música, brinquedos e teatro. Amenizar o estresse da hospitalização com adequação ambi...

  14. Desinfeção aplicada aos cones de guta-percha

    OpenAIRE

    Flor, Eduardo Rafael de Lima

    2015-01-01

    Introdução: Ao longo do tempo o Tratamento Endodôntico Não Cirúrgico tem sido das áreas da Medicina Dentária que mais tem evoluído. Todos os passos do tratamento têm sido revistos de forma a aumentar a taxa de sucesso. O controlo microbiológico é crucial para que o tratamento seja um sucesso a curto, médio e longo prazo. A assepsia deve ser mantida em todas as fases deste tratamento para que este seja um sucesso. Objetivo: Ao longo do meu percurso académico pude concluir que...

  15. [Study on Provenance of Kraak Porcelains from "Nan'ao I" Shipwreck].

    Science.gov (United States)

    Du, Jing-nan; Chen, Yue; Li, Nai-sheng; Ming, Chao-fang; Zhu, Jian; Luo, Wu-gan

    2015-06-01

    The "Kraak Porcelain" was a kind of Blue and White Porcelain which exported from China to Europe in Ming and Qing period. The study of Kraak Porcelain is a focus issue in international field of porcelain research. In 2007, the discovery of "Nan'ao I" Shipwreck of Ming Dynasty and the porcelains loaded in it, provided precious materials for the research on Kraak Porcelain. In this paper, we explored the provenance of 10 Kraak Porcelain samples from Nan'ao I, using both traditional visual method and WDXRF. PMID:26601402

  16. The Magellan Adaptive Secondary VisAO Camera: Diffraction- Limited Broadband Visible Imaging and 20mas Fiber Array IFS

    OpenAIRE

    Kopon, Derek; Close, Laird M; Males, Jared R.; Gasho, Victor; Follette, Katherine

    2010-01-01

    The Magellan Adaptive Secondary AO system, scheduled for first light in the fall of 2011, will be able to simultaneously perform diffraction limited AO science in both the mid-IR, using the BLINC/MIRAC4 10\\{mu}m camera, and in the visible using our novel VisAO camera. The VisAO camera will be able to operate as either an imager, using a CCD47 with 8.5 mas pixels, or as an IFS, using a custom fiber array at the focal plane with 20 mas elements in its highest resolution mode. In imaging mode, t...

  17. The repair of ground cover of Bolivia-Brazil gas pipeline near Paraguay River crossing, in a swamp soft soil region, using geo synthetics reinforced backfilling; Reparo da cobertura do gasoduto Bolivia-Brasil junto ao Rio Paraguai, em trecho com solo mole, utilizando aterro reforcado com geosinteticos

    Energy Technology Data Exchange (ETDEWEB)

    Costa, Cesar Augusto; Jorge, Kemal Vieira; Bechuate Filho, Pedro [TBG - Transportadora Brasileira Gasoduto Bolivia Brasil S.A., Campo Grande, MS (Brazil). Gerencia Regional Centro Oeste (CRGO); Teixeira, Sidnei H.C. [Geohydrotech Engenharia S.C. Ltda., Braganca Paulista, SP (Brazil)

    2005-07-01

    TBG - Transportadora Gasoduto Bolivia-Brasil S.A, executes routine maintenance works at the Gas Pipeline Right of Way, seeking its integrity. In the wetlands of Pantanal, near the Paraguay river crossing, the organic-alluvial soil was submitted to the process of subsidence. This process, associated with the river water flow erosion, shrank the soil volume and diminished or extinguished the pipeline land cover. The pipeline was exposed to the environment, and submitted to tension stresses and the risk of low cycle fatigue during the floods. The cathodic protection system also had to be evaluated, specially in the drought. To mitigate the problem, the embankment technique was adopted using sandy soil, reinforced with polyester geo-webs and with woven polipropene geo-textiles. The solution also used geo-webs with soil-cement as protection elements against the degradation of the geo-textiles blankets. Some monitoring works are associated with those interventions: monitoring of cathodic protection; topographical verification of horizontal and vertical displacements of the pipeline; levels of land covering, and rainfalls and flood measurement. The base of the embankment was built with hydraulic transported soil, and at the end consistently supported the gas pipeline. (author)

  18. Pseudoscorpions of the genus Aphelolpium (Pseudoscorpionida, Olpiidae) from Curaçao, Aruba and Bonaire

    NARCIS (Netherlands)

    Tooren, van den D.

    1995-01-01

    Tooren, D. van den, 1995. Pseudoscorpions of the genus Aphelolpium (Pseudoscorpionida, Olpiidae) from Curaçao, Aruba and Bonaire. Studies Nat. Hist. Caribbean Region 72. Amsterdam, 1995: 69-97. A large number of new localities of the pseudoscorpion Aphelolpium scitulum Hoff, 1964 from Curacao, Aruba

  19. Biology of the Graysby, Epinephelus cruentatus, of the coral reef of Curaçao

    NARCIS (Netherlands)

    Nagelkerken, W.P.

    1979-01-01

    Epinephelus (Cephalopholis) cruentatus (Lacépède, 1802) [Petrometopon cruentatum], the Graysby, is one of the most common groupers on the coral reef at the southwest coast of Curaçao. They are very abundant at a depth from 7½ to 9 m. A second, lower maximum in their vertical distribution is found at

  20. A new species of the Rodent Baiomys from Aruba and Curaçao

    NARCIS (Netherlands)

    Husson, A.M.

    1960-01-01

    In his paper on the mammals of the islands of Aruba, Curaçao, and Bonaire (situated off the north coast of Venezuela), WAGENAAR HUMMELINCK (1940 a, p. 69) mentioned a juvenile specimen of a cricetine rodent which was identified by Mr. M. A. C. HINTON and Mr. R. W. HAYMAN as probably belonging to the

  1. Characteristics of SAO and AO in equatorial middle atmospheric temperature pattern

    International Nuclear Information System (INIS)

    Complete text of publication follows. More than 10 years (1998-2008) of data from a low latitude station, Gadanki, India (13.5deg N, 79.2deg E), has been utilized to measure middle atmospheric temperature pattern, using lidar and TIMED/SABER, which exhibits the presence of semi-annual oscillation (SAO) and annual oscillation (AO). AO component is stronger in mesospheric region (80-90 km) and SAO is dominant at stratospheric altitudes (30-50 km). Overall, AO possesses higher amplitude ∼ 6 K, and SAO shows relatively less amplitude ∼ 1-2 K. AO at 90 km, has its crest around summer solstice, and the same at 80 shows peak around winter solstice with a downward progression speed ∼ 1.67 km/month. SAO propagates downward with an average phase speed ∼ 7 km/month and its phase maximizes around equinox and solstice at 50 and 30 km, respectively. Observed SAO has also shown seasonal asymmetry in the peak.

  2. High prevalence of dermal parasites among coral reef fishes of Curaçao

    NARCIS (Netherlands)

    M.A. Bernal; S.R. Floeter; M.R. Gaither; G.O. Longo; R. Morais; C.E.L. Ferreira; M.J.A. Vermeij; L.A. Rocha

    2015-01-01

    During expeditions to Curaçao in August and October of 2013, a large number of fish infected with dermal parasites was observed. Infected individuals presented black spots and white blemishes on their skin and fins that were easily observed by divers, and which have been associated with infections b

  3. Molecular Evidence for Dissemination of Unique Campylobacter jejuni Clones in Curaçao, Netherlands Antilles

    NARCIS (Netherlands)

    Duim, B.; Godschalk, P.C.R.; Braak, N. van den; Dingle, K.E.; Dijkstra, J.R.; Leyde, E.; Plas, J. van der; Colles, F.M.; Endtz, H.P.; Wagenaar, J.A.; Maiden, M.C.J.; Belkum, A. van

    2003-01-01

    Campylobacter jejuni isolates (n = 234) associated with gastroenteritis and the Guillain-Barré syndrome (GBS) in the island of Curaçao, Netherlands Antilles, and collected from March 1999 to March 2000 were investigated by a range of molecular typing techniques. Data obtained by pulsed-field gel ele

  4. Subsea (0-40 m) terraces and benches, windward off Curaçao, Netherlands Antilles

    NARCIS (Netherlands)

    Focke, J.W.

    1978-01-01

    At the windward (NE) side of Curaçao at least two well-developed submarine terraces occur. A first, rocky, terrace, 100 to 150 m wide at depths of 5 m inshore to 12-15 m at the drop off, is densely covered with Sargassum. A second, sandy, terrace, approximately 50 to 100 m wide at depths of 32 to 40

  5. O suicídio como questão: melancolia e passagem ao ato

    Directory of Open Access Journals (Sweden)

    Marcos Vinicius Brunhari

    2014-06-01

    Full Text Available O artigo toma a questão do suicídio na obra de Freud como um problema de pesquisa que interroga certos pontos de sua metapsicologia: a possibilidade de uma tendência à autodestruição, o papel do eu e, finalmente, a dimensão do objeto que estaria implicada. É em relação a este último, em particular a seu estatuto na articulação que Freud propõe entre suicídio e melancolia, que o trabalho de Lacan em torno do objeto a, associado à passagem ao ato e à melancolia no Seminário, livro 10 - A angústia (1962-1963/2005, figura, no artigo, como um acréscimo à investigação iniciada por Freud. Essa referência lacaniana permitirá destacar a presença fulgurante do objeto a no momento da passagem ao ato suicida, estabelecendo uma articulação com a identificação melancólica descrita por Freud em seu "Luto e melancolia" (1917 [1915]/1969. A essa identificação absoluta ao objeto em questão é correlata a ausência de um sujeito e a ruptura mais radical em relação ao Outro.

  6. Improvement of phase diversity algorithm for non-common path calibration in extreme AO context

    Science.gov (United States)

    Robert, Clélia; Fusco, Thierry; Sauvage, Jean-François; Mugnier, Laurent

    2008-07-01

    Exoplanet direct imaging with a ground-based telescope needs a very high performance adaptive optics (AO) system, so-called eXtreme AO (XAO), a coronagraph device, and a smart imaging process. One limitation of AO system in operation remains the Non Common Path Aberrations (NCPA). To achieve the ultimate XAO performance, these aberrations have to be measured with a dedicated wavefront sensor placed in the imaging camera focal plane, and then pre-compensated using the AO closed loop process. In any events, the pre-compensation should minimize the aberrations at the coronagraph focal plane mask. An efficient way for the NCPA measurement is the phase diversity technique. A pixel-wise approach is well-suited to estimate NCPA on large pupils and subsequent projection on the deformable mirror with Cartesian geometry. However it calls for a careful regularization for optimal results. The weight of the regularization is written in close-form for un-supervised tuning. The accuracy of NCPA pre-compensation is below 8 nm for a wide range of conditions. Point-by-point phase estimation improves the accuracy of the Phase Diversity method. The algorithm is validated in simulation and experimentally. It will be implemented in SAXO, the XAO system of the second generation VLT instrument: SPHERE.

  7. Performance of a MEMS-based AO-OCT system using Fourier Reconstruction

    Energy Technology Data Exchange (ETDEWEB)

    Evans, J; Zawadzki, R; Jones, S; Olivier, S; Werner, J S

    2009-01-21

    Adaptive optics (AO) and optical coherence tomography (OCT) are powerful imaging modalities that, when combined, can provide high-resolution (3.5 {micro}m isotropic), 3-D images of the retina. The AO-OCT system at UC Davis has demonstrated the utility of this technology for microscopic, volumetric, in vivo retinal imaging. The current system uses an AOptix bimorph deformable mirror (DM) for low-order, high-stroke correction and a 140-actuator Boston Micromachines DM for high-order correction. Developments to improve performance or functionality of the instrument are on-going. Based on previous work in system characterization we have focused on improved AO control. We present preliminary results and remaining challenges for a newly implemented Fourier transform reconstructor (FTR). The previously reported error budget analysis is also reviewed and updated, with consideration of how to improve both the amount of residual error and the robustness of the system. Careful characterization of the AO system will lead to improved performance and inform the design of future systems.

  8. Modelo An\\'alogo Ac\\'ustico ao Buraco Negro de Schwarzschild

    CERN Document Server

    Toniato, Júnior Diniz

    2011-01-01

    Um fluido em movimento pode agir sobre o som da mesma forma que os espa\\c{c}o-tempos curvos podem influenciar na trajet\\'oria da luz na relatividade geral. Com isso, pode-se descrever a propaga\\c{c}\\~ao dessas ondas sonoras atrav\\'es de uma m\\'etrica efetiva, sob a qual elas seguir\\~ao geod\\'esicas nulas. Esta disserta\\c{c}\\~ao faz uma revis\\~ao destes estudos concentrando-se em uma analogia ac\\'ustica para um buraco negro de Schwarzschild, demonstrando suas vantagens e limita\\c{c}\\~oes quando aplicada para o estudo da teoria de Hawking. A fluid in moviment can act on the sound the same way that curved space-time can influence on light trajectory in the general relativity. So, one can describe the propagation these sound waves through an effective metric, under wich they will follow null geodesics. This thesis makes a review of these studies focusing in an analogy to Schwarzschild black hole using an acoustic system, showing its advantages and limitations when applied in the study of Hawking's theory.

  9. Dynamic SPECT of the brain using a lipophilic technetium-99m complex, PnAO

    DEFF Research Database (Denmark)

    Holm, S; Andersen, A R; Vorstrup, S;

    1985-01-01

    The lipophilic 99mTc-labeled oxime propylene amine oxime (PnAO) should, according to recent reports behave like 133Xe in the human brain. This study compares SPECT images of the two tracers in six subjects: four stroke cases, one transitory ischemic attack case and one normal subject. Technetium-99...

  10. Long-term functional outcome of mandibular reconstruction with stainless steel AO reconstruction plates

    NARCIS (Netherlands)

    van Minnen, B; Nauta, JM; Vermey, A; Bos, RRM; Roodenburg, JLN

    2002-01-01

    Mandibular continuity defects are usually reconstructed with bone grafts. However, factors associated with the tumour and the patient can still be reasons to choose reconstruction plates. The aim of this study was to find out the results of mandibular reconstructions with stainless steel AO reconstr

  11. Doença periodontal materna como fator associado ao baixo peso ao nascer Maternal periodontal disease as a factor associated with low birth weight

    Directory of Open Access Journals (Sweden)

    Simone Seixas da Cruz

    2005-10-01

    Full Text Available OBJETIVO: Estudos recentes têm apresentado evidências de que a doença periodontal em gestantes pode ser um dos determinantes do baixo peso ao nascer. Realizou-se estudo para verificar a existência de associação entre doença periodontal materna e baixo peso ao nascer. MÉTODOS: Estudo do tipo caso-controle com 302 mulheres, sendo 102 mães de nascidos vivos de baixo peso (grupo caso e 200 mães de nascidos vivos com peso normal (grupo controle. A existência de associação entre doença periodontal e baixo peso ao nascer foi avaliada mediante modelo multivariado de regressão logística, considerando outros fatores de risco para o baixo peso. RESULTADOS: Ambos os grupos de mães eram comparáveis no que se refere a idade, altura, peso pré-gestacional, tabagismo, alcoolismo, doenças prévias, estado civil, situação socioeconômica, número de escovações e uso de fio dental, número de refeições diárias, e visitas ao dentista. A doença periodontal foi diagnosticada em 57,8% das mães do grupo caso e 39,0% do grupo controle. A análise de regressão logística indicou associação positiva entre doença periodontal e baixo peso ao nascer (ORbruto=2,15; IC 95%: 1,32-3,48, especialmente entre as mães com escolaridade menor ou igual a quatro anos (ORajustada=3,98; IC 95%: 1,58-10,10. CONCLUSÕES: A doença periodontal é um possível fator de risco para o baixo peso ao nascer.OBJECTIVE: Recent studies have presented evidence that periodontal disease in pregnant women may be a determining factor for low birth weight. The present investigation was carried out to verify whether or not there is an association between maternal periodontal disease and low birth weight. METHODS: This was a case-control study on 302 women, of whom 102 were the mothers of live newborns of low weight (case group and 200 were the mothers of live newborns of normal birth weight (control group. The existence of an association between periodontal disease and low

  12. The complexity of national identity Construction in Curaçao, Dutch Caribbean

    Directory of Open Access Journals (Sweden)

    Rose Mary Allen

    2010-10-01

    Full Text Available Curaçao, one of the five islands of the Dutch Caribbean federation called the Netherlands Antilles, currently stands at a crossroad of constitutional reform. In the context of these changes at the political level, it is logical that national identities are being redefined and repositioned. The developments in the fashioning of national identities in Curaçao deserve attention locally but also regionally. How do people in Curaçao construct national identities in daily life? How is a national collective constructed on the one hand, and how are differences with other collectivities constructed on the other hand? The historical context of constitutional changes that have occurred over the years is considered as well as an examination of the present discourse on constitutional reform. These identity issues are then placed within a wider Caribbean context.  Resumen: La complejidad de la construcción de la identidad nacional en Curaçao,en el Caribe holandés Curaçao, una de las cinco islas de la federación caribeña neerlandesa llamada Antillas Holandesas, se encuentra hoy en día en una encrucijada de reformas constitucionales. En el contexto de estos cambios a nivel político, es lógico que las identidades nacionales sean redefinidas y reposicionadas. Los desarrollos en la formulación de identidades nacionales en Curaçao merecen atención local, y también regional. ¿Cómo construye la gente en Curaçao identidades nacionales en la vida cotidiana? ¿Cómo, por un lado, se construye el colectivo nacional y, por otro, cómo se construyen las diferencias con otras colectividades? En este análisis se estudia el contexto histórico de los cambios constitucionales que han ocurrido en el curso del tiempo y se realiza igualmente una revisión del actual discurso sobre la reforma constitucional. Estos problemas de identidad son analizados entonces en un contexto caribeño más amplio.

  13. Resistência ao clopidogrel: prevalência e variáveis associadas

    Directory of Open Access Journals (Sweden)

    Fabrício Braga da Silva

    2012-12-01

    Full Text Available FUNDAMENTO: A dupla terapia antiagregante plaquetária com ácido acetilsalicílico e clopidogrel é pedra angular do tratamento de pacientes submetidos a angioplastia com implante de stents coronarianos. Todavia, parte desses pacientes, a despeito do uso de aspirina e clopidogrel, não se encontram eficazmente antiagregados, fenômeno conhecido como resistência aos antiagregantes plaquetários. A sua prevalência, assim como as condições a ela relacionadas são desconhecidas em nosso meio. OBJETIVO: Determinar a prevalência de resistência ao clopidogrel, assim como as variáveis a ela relacionadas. MÉTODOS: Pacientes admitidos para angioplastia eletiva em uso crônico de aspirina e clopidogrel entre janeiro de 2007 e janeiro de 2010. Uma hora após o procedimento, foi medida a agregação plaquetária utilizando a agregometria óptica com difosfato de adenosina 5 µmoles/l como agonista. Nesse momento, em um coorte transversal, determinou-se a prevalência de resistência ao clopidogrel, definida com um valor de agregação plaquetária > 43% e um modelo de regressão logística às variáveis a ela relacionadas. RESULTADOS: Foram analisados 205 pacientes (66,4 ± 11anos, 61,5% masculino. A prevalência de resistência ao clopidogrel foi 38,5% (IC95% 31,9 - 45,2%. O valor da glicemia (OR = 1,014 IC95% 1,004 - 1,023, infarto do miocárdio prévio (OR = 2,320 IC95% 1,1103 - 4,892 e a resposta terapêutica à aspirina (OR = 1,057 IC95% 1,017 - 1,099 foram as variavéis de associação independente à resistência ao clopidogrel. CONCLUSÃO: A prevalência de resistência ao clopidogrel foi alta. Glicemia, infarto agudo do miocárdio prévio e a resposta ao ácido acetilsalicílico foram variáveis a ela relacionadas. A melhor compreensão desse fenômeno se faz necessária frente às novas propostas de antiagregantes plaquetários.

  14. Determinantes psicofisiológicos da resposta ao stress : aspectos do desenvolvimento e adaptação ao cancro da mama

    OpenAIRE

    Eusébio, Susana Filipa Gonçalves, 1983-

    2013-01-01

    Tese de mestrado, Neurociências, Faculdade de Medicina, Universidade de Lisboa, 2013 A investigação tem sustentado que os estilos de vinculação, relativamente estáveis ao longo do desenvolvimento, parecem influenciar o modo como os indivíduos respondem a situações de stress na vida adulta. Os esquemas cognitivos de vinculação insegura, associados a emoções negativas, parecem frequentemente relacionar-se com a doença física ou mental, verificando-se nesse contexto mecanismos psicobiológicos...

  15. Resistência de Eleusine indica aos inibidores de ACCase Eleusine indica resistance to ACCase inhibitors

    Directory of Open Access Journals (Sweden)

    R.A. Vidal

    2006-01-01

    Full Text Available Dentre as causas da ineficácia no controle de plantas daninhas destaca-se a resistência delas aos herbicidas. Os objetivos deste trabalho foram avaliar a suspeita de resistência de Eleusine indica a inibidores de acetil-CoA carboxilase (ACCase e investigar a ocorrência de resistência cruzada entre os inibidores de ACCase. Biótipo de Eleusine indica originado do Mato Grosso com suspeita de resistência aos herbicidas inibidores de ACCase foi avaliado em casa de vegetação na sua suscetibilidade para diversos produtos do grupo dos ariloxifenoxipropionatos e cicloexanodionas. Estudos de resposta à dose confirmaram que o biótipo era 18 vezes mais insensível ao sethoxydim do que biótipo suscetível nunca aspergido com herbicidas. Também se constatou resistência cruzada ao fenoxaprop, cyhalofop, propaquizafop e butroxydim. Não se observou resistência cruzada aos produtos fluazifop, haloxyfop, quizalofop e clethodim.Among the causes for weed control inefficacy, the worst one is resistance to herbicides. The objectives of this work were to evaluate an Eleusine indica biotype suspected of resistance to ACCase inhibitors and to investigate the occurrence of cross- resistance to several ACCase inhibitors. One biotype of Eleusine indica originated from Mato Grosso with suspected resistance to ACCase inhibitors was evaluated in a greenhouse in relation to its susceptibility to several products of the ariloxyphenoxypropionate and cyclohexanedione groups. Studies on dose response confirmed that the suspected biotype was 18 times more insensitive to sethoxydim than the susceptible biotype that had never been treated with herbicides. Cross-resistance was confirmed for fenoxaprop, cyhalofop, propaquizafop and butroxydim. No cross-resistance was observed with fluazifop, haloxyfop, quizalofop, and clethodim.

  16. Altura materna e peso da criança ao nascer Maternal height and birth weight

    Directory of Open Access Journals (Sweden)

    Euclides Ayres de Castilho

    1976-09-01

    Full Text Available Numa população de 498 gestantes sadias matriculadas no Centro de Saúde Geraldo Paula Souza, foi estudada a relação entre a altura materna e o peso da criança ao nascer, segundo a técnica de análise de regressão múltipla, tipo "stepwise", utilizando-se o subprograma "regression", componente do sistema "Statistical Package for Social Sciences" - SPSS. Essa técnica permite isolar o efeito de cada fator ajustado para a presença dos efeitos de outros fatores. O peso da criança ao nascer mostrou-se associado à idade gestacional, peso médio da gestante no 3.° trimestre da gravidez e ao sexo do recém-nascido, a um nível de significância de 5%. Idade materna, peso médio da gestante no 2.° trimestre da gravidez, altura materna e ordem de nascimento do recém-nascido não se mostraram associados com o peso ao nascer, ao citado nível de significância.The relationship between maternal height and birth weight was studied using a multiple regression approach with a "stepwise" solution. In the final stage of that procedure no correlation was found between maternal height and birth weight given the regression on gestational age, maternal weight, sex and birth order of the fetus.

  17. Aumento da imunorreatividade ao VEGFR-1 no complexo coroido-escleral em modelo experimental de hipercolesterolemia

    Directory of Open Access Journals (Sweden)

    Rogil José de Almeida Torres

    2013-02-01

    Full Text Available OBJETIVO: O objetivo deste trabalho é investigar a expressão do fator de crescimento vascular endotelial (VEGF na coroide e esclera, utilizando um modelo experimental de hipercolesterolemia. MÉTODO: Coelhos New Zealand foram organizados em dois grupos: O grupo dieta normal (GN, composto por 8 coelhos (8 olhos, recebeu ração padrão para coelhos, durante 4 semanas; e o grupo hipercolesterolêmico (GH, composto por 13 coelhos (13 olhos, recebeu dieta rica em colesterol a 1% por 8 semanas. Foi realizada a dosagem sérica de colesterol total, triglicerídeos, HDL colesterol, glicemia de jejum no início do experimento e no momento da eutanásia. Ao final da 8ª semana para o GH e 4ª semana para o GN foi realizada a eutanásia dos animais e os olhos foram submetidos à análise imuno-histoquímica com os anticorpos RAM-11 e VEGFR-1. RESULTADOS: Observou-se significativo aumento do colesterol total e triglicerídeos do GH em relação ao GN (p<0,001. Houve significativo aumento da expressão da RAM-11 e VEGFR-1 na coroide e esclera dos animais do GH em relação ao GN (p<0,001. CONCLUSÃO: Este estudo demonstra que a dieta hipercolesterolêmica em coelhos induz ao aumento da concentração de macrófagos e da imunorreatividade ao VEGFR-1 na coroide e esclera, expressando similaridade com a degeneração macular relacionada à idade (DMRI humana.

  18. 粘附因子CD44v3在正常绒毛和葡萄胎中的表达及相关性研究%Expression of CD44 v3 and Their Correlation in Normal Placetal Villi and Hydatidiform Mole

    Institute of Scientific and Technical Information of China (English)

    白兴武

    2011-01-01

    目的:探讨CD44v3在正常绒毛和葡萄胎中的表达及相关性.方法:采用免疫组化SABC法检测CD44v3在50例正常绒毛,50例良性葡萄胎,40例恶性葡萄胎的表达情况.结果:CD44v3在正常绒毛,良性葡萄胎,恶性葡萄胎中阳性表达率分别是:8.0%,30.6%,90.0%,组间比较差异有统计学意义(P<0.05).结论:CD44v3的过表达促进葡萄胎的浸润、转移,可作为葡萄胎的浸润、转移及评价预后生物学指标.%Objective: To investigate the expression of CD44 v3 and their correlation in normal placetal villi and hydatidiform mole. Method: The expression of CD44 v3 protein was detected in 50 specimens nomal placetal villi ,50 specimens benign hydatidiform mole and 40 specimens of malignant hydatidiform mole by immunohistochemistry (SABC method ). Result: In normal placetal villi, benign hydatidiform mole, malignant hydatidiform mole ,the expression rate of CD44 v3 were 8.0%, 30.6% and 90.0% respectively . Conclusion:The expressions of CD44v3 are correlated to invasion and metastasis of hydatidiform mole, thus can be as markers to predict metastasis and invasion of hydatidiform mole and the prognosis of these patients as well.

  19. Restriçao energética e propilenoglicol na prevençao da cetose e na produtividade de vacas holandesas de alta produçao

    OpenAIRE

    Vinne, Roger Van Der; Andriguetto, Jose Luciano

    2012-01-01

    Neste trabalho foram avaliadas técnicas que visam a prevenção da cetose e a diminuição do balanço energético negativo em vacas leiteiras de alta produção, com o objetivo de melhorar o desempenho produtivo destes animais. Vacas da raça holandesa (33 animais) com média de produção acima de 30 kg de leite por dia foram distribuídas em quatro grupos. Foram feitos os seguintes tratamentos: o primeiro grupo era o controle; o segundo recebeu a suplementação de 500 g de propileno glicol ao dia por vi...

  20. A new species of Hemicyclops (Crustacea, Copepoda, Poecilostomatoida, Clausidiidae) associated with hermit crabs in Curaçao

    NARCIS (Netherlands)

    Stock, Jan H.

    1992-01-01

    STOCK, J. H. 1992. A new species of Hemicyclops (Crustacea, Copepoda, Poecilostomatoida, Clausidiidae) associated with hermit crabs in Curaçao. Stud. Nat. Hist. Caribbean Region 71, Amsterdam 1992: 69-78. Hemicyclops geminatus n. sp. is described from the upper infralittoral zone of Curaçao (Antille

  1. Resistência de genótipos de caupi ao caruncho

    Directory of Open Access Journals (Sweden)

    BARRETO PAULO DIÓGENES

    2000-01-01

    Full Text Available A utilização de resistência genética ao ataque de Callosobruchus maculatus (Fabr. tem sido alvo de investigação científica, especialmente no que diz respeito à identificação de fontes de resistência. O presente trabalho objetivou incorporar, ao grupo de caracteres desejáveis para o cultivo de caupi (Vigna unguiculata (L. Walp., resistência genética ao caruncho (C. maculatus. Foram realizadas hibridações dos genótipos IT81D-1045 e IT81D-1064 (portadores de resistência ao inseto com CNCx 252-1E/FB, CNCx 187-22D-1 e BR 1-Poty (capazes de transferir resistência a viroses, tolerância à seca, formação de grãos com padrão comercial, elevado potencial de produção e adaptabilidade a diferentes condições ambientais. Populações segregantes obtidas destes cruzamentos foram conduzidas pelo método SPD (descendência de uma única vagem, e na geração F5 foram realizadas seleções individuais. As linhagens obtidas foram avaliadas em conjunto com materiais de origens diferentes, utilizando-se parâmetros associados à infestação da praga. Foi constatado que os genótipos avaliados apresentaram variabilidade quanto à preferência à postura, número de insetos emergidos e número de sementes danificadas; as linhas EVx 37-15E e EVx 37-2E foram as que sofreram menor dano causado pelo caruncho; as variáveis número de ovos, número de insetos emergidos e número de sementes danificadas mostraram-se positiva e significativamente correlacionadas entre si; o grupo das linhagens que descendem de genitores resistentes apresenta valores significativamente inferiores aos obtidos pelas demais, o que indica que a resistência ao inseto se transmite geneticamente.

  2. Resistência ao cisalhamento de solos e taludes vegetados com capim vetiver

    Directory of Open Access Journals (Sweden)

    Michele Cristina Rufino Barbosa

    2013-02-01

    Full Text Available Taludes vegetados são mais resistentes contra movimentos de massa e erosão pela água. A vegetação contribui para a estabilidade do solo, principalmente pelo aumento da resistência ao cisalhamento por meio do reforço oferecido pelas raízes. As espécies vegetais que mais têm sido eficientes na estabilização de taludes instáveis são as gramíneas, pertencentes à família Poaceae. Um exemplar dessa família, capim vetiver (Chrysopogonzizanioides (L. Roberty, tem se revelado muito eficaz nessa estabilização. Com o objetivo de avaliar a melhoria dos parâmetros de resistência ao cisalhamento oferecida ao solo pelas raízes do capim vetiver com o tempo de plantio, realizaram-se experimentos de cisalhamento direto por meio de amostras indeformadas de solo sem vegetação e cultivadas com capim vetiver na idade de um, dois, três e quatro anos de plantio. Também foram realizados experimentos de cisalhamento direto em talude do mesmo solo sem vegetação e com cobertura desse capim. Os resultados do ensaio de cisalhamento direto das amostras de talude de solo foram avaliados por três métodos de equilíbrio limite para verificação de um fator de segurança médio nos taludes. A partir dos ensaios de cisalhamento direto, determinaram-se os parâmetros de resistência ao cisalhamento (intercepto de coesão e ângulo de atrito interno, verificando que o capim vetiver proporcionou incremento de coesão aparente ao solo, sendo esse destacado após três anos de plantio do capim. Esse capim promoveu melhoria nos parâmetros de resistência com consequente elevação do fator de segurança de taludes e aumento da resistência ao cisalhamento de solos, o que auxiliou na estabilização de taludes em planos superficiais de ruptura.

  3. Isolation and characterization of an agaro-oligosaccharide (AO-hydrolyzing bacterium from the gut microflora of Chinese individuals.

    Directory of Open Access Journals (Sweden)

    Miaomiao Li

    Full Text Available Agarose (AP from red algae has a long history as food ingredients in East Asia. Agaro-oligosaccharides (AO derived from AP have shown potential prebiotic effects. However, the human gut microbes responsible for the degradation of AO and AP have not yet been fully investigated. Here, we reported that AO and AP can be degraded and utilized at various rates by fecal microbiota obtained from different individuals. Bacteroides uniformis L8 isolated from human feces showed a pronounced ability to degrade AO and generate D-galactose as its final end product. PCR-DGGE analysis showed B. uniformis to be common in the fecal samples, but only B. uniformis L8 had the ability to degrade AO. A synergistic strain, here classified as Escherichia coli B2, was also identified because it could utilize the D-galactose as the growth substrate. The cross-feeding interaction between B. uniformis L8 and E. coli B2 led to exhaustion of the AO supply. Bifidobacterium infantis and Bifidobacterium adolescentis can utilize one of the intermediates of AO hydrolysis, agarotriose. Growth curves indicated that AO was the substrate that most favorably sustained the growth of B. uniformis L8. In contrast, κ-carrageenan oligosaccharides (KCO, guluronic acid oligosaccharides (GO, and mannuronic acid oligosaccharides (MO were found to be unusable to B. uniformis L8. Current results indicate that B. uniformis L8 is a special degrader of AO in the gut microbiota. Because B. uniformis can mitigate high-fat-diet-induced metabolic disorders, further study is required to determine the potential applications of AO.

  4. Resistencia natural de oito especies de madeiras do Norte e Nordeste do Brasil aos xilofagos marinhos

    OpenAIRE

    Serpa, Fernando da Gama

    2013-01-01

    A presente pesquisa visou avaliar a resistência natural de oito espécies de madeiras do Norte e Nordeste do Brasil aos xilófagos marinhos, com a finalidade de conhecer madeiras resistentes e suscetíveis aos xilófagos; relacionar a resistência das madeiras com o seu teor de sílica e alcalóides; definir o grau de ataque dos xilófagos; estabelecer um método padrão para determinar a resistência de madeiras em estado natural e preserva das contra o ataque dos xilófagos e aplicar método de visualiz...

  5. CANARY phase B: on-sky open-loop tomographic LGS AO results

    Science.gov (United States)

    Morris, Tim; Gendron, Eric; Basden, Alastair; Martin, Olivier; Osborn, James; Henry, David; Hubert, Zoltan; Sivo, Gaetano; Gratadour, Damien; Chemla, Fanny; Sevin, Arnaud; Cohen, Matthieu; Younger, Eddy; Vidal, Fabrice; Wilson, Richard; Butterley, Tim; Bitenc, Urban; Reeves, Andrew; Bharmal, Nazim; Raynaud, Henri-François; Kulcsar, Caroline; Conan, Jean-Marc; Huet, Jean-Michel; Perret, Denis; Dickson, Colin; Atkinson, David; Bailie, Tom; Longmore, Andy; Todd, Stephen; Talbot, Gordon; Morris, Simon; Rousset, Gérard; Myers, Richard

    2014-07-01

    CANARY is an on-sky Laser Guide Star (LGS) tomographic AO demonstrator that has been in operation at the 4.2m William Herschel Telescope (WHT) in La Palma since 2010. In 2013, CANARY was upgraded from its initial configuration that used three off-axis Natural Guide Stars (NGS) through the inclusion of four off-axis Rayleigh LGS and associated wavefront sensing system. Here we present the system and analysis of the on-sky results obtained at the WHT between May and September 2014. Finally we present results from the final `Phase C' CANARY system that aims to recreate the tomographic configuration to emulate the expected tomographic AO configuration of both the AOF at the VLT and E-ELT.

  6. Resistência ao fogo de alvenarias sem função estrutural

    OpenAIRE

    Oliveira, Filipa Sofia Nunes

    2014-01-01

    Um incêndio é algo difícil de prever, assim como a sua consequência nos elementos de construção. Dessa forma, ao longo das últimas décadas, os elementos de construção têm sido alvo de diversos estudos a fim de avaliar os seus comportamentos quando solicitados em situação de incêndio. O International Building Code (IBC) descreve um método de cálculo analítico para a determinação da resistência ao fogo dos elementos da construção de acordo com os procedimentos de teste estabelecidos na ASTM ...

  7. Crítica ao postulado positivista da psicologia: de Heidegger a Foucault

    OpenAIRE

    Rômulo Marques dos Santos Ballestê; Ricardo de Barros Cabral

    2012-01-01

    A objetivação do ser humano, que segue os ideais de precisão das ciências físico-matemáticas, bem como a sua identificação com o fato biológico, orienta o projeto de ciência da psicologia, desde o século XIX. Michel Foucault aponta esta questão como um paradoxo. A redução do ser humano a objeto dado se mostra contrária às considerações de Martin Heidegger ao tratar do problema do Ser. Portanto, partindo das observações desses dois autores, será realizada uma crítica ao modelo positivista de c...

  8. A censura aos filmes ibero-americanos na governação de Marcello Caetano

    OpenAIRE

    Morais, Ana Bela

    2014-01-01

    Através do estudo dos processos de censura ao filmes hispano-americanos em Portugal durante os anos de governação de Marcello Caetano (finais de 1968-1974), pretendo investigar os critérios da Comissão de Censura em relação ao modo como eram censurados esses filmes. O presente trabalho apoia-se no estudo dos arquivos do Secretariado Nacional da Informação e Turismo. A informação produzida pela Comissão de Exame e Classificação de Espectáculos, durante o Estado Novo, está concentrada neste esp...

  9. O exercício do estudar nos cursinhos destinados aos concursos públicos

    Directory of Open Access Journals (Sweden)

    Leonardo Del Puppo Luz

    2008-06-01

    Full Text Available O artigo discute o processo de produção da subjetividade contemporânea elaborado sobre o Estudar em alunos de cursinhos destinados aos concursos públicos. Procura-se discutir as tecnologias de poder, sobretudo na relação saber-poder, engendradas nestes "ambientes educacionais", já que tais construções sobre o Estudar produzem e perpetuam a manifestação de conceitos absolutos e verdadeiros de se pensar o estudo por meio de técnicas e procedimentos de funcionamentos ideais e idealizados. Busca-se problematizar este modelo homogêneo baseado no tecnicismo do estudar e nas falas sobre o verdadeiro visando colocar em análise o estereótipo do "fracasso" atrelado aos alunos vinculados a estes locais.

  10. A escola "Rocha" ao espelho : relação com a comunidade

    OpenAIRE

    Macieira, Maria da Graça Vareiro

    2012-01-01

    O relatório que agora se apresenta sustenta-se na pesquisa diversificada abaixo inserta – nos conceitos que foram as ferramentas de leitura da realidade e os pressupostos de interpretação dessa vivência – e do percecionado e apreendido, ao longo dos anos, em contexto da Comunidade Educativa – aplicação dos conceitos teóricos à interpretação da realidade –, nomeadamente na Escola Secundária Rocha Peixoto, aqui, ao espelho e numa lógica de relação escola-comunidade. Mobilizada a prática pedagóg...

  11. Sindrome da Cutis Laxa Ligada ao X: Caso Clínico

    OpenAIRE

    Lobo, Ana Luísa; Teixeira, Sandra; Tomás, Edite; Azevedo, Afonso; Reis, Armando

    2014-01-01

    A Síndrome da Cutis Laxa Ligada ao X ou síndrome do "Corno Occipital" é uma doença genética rara, de transmissão recessiva ligada ao cromossoma X, associada a um defeito do metabolismo do cobre.Apresenta-se um caso clínico deste síndrome numa criança com hiperlaxidez articular, hérnias inguinais recidivantes, fragilidade cutânea e ainda malformação urológica associando uma obstrução pieloureteral à direita e volumosos divertículos vesicais. Salienta-se o facto da obstrução da junção pielouret...

  12. Evaluation of the reproducibility of the AO/ASIF classification for humeral shaft fractures☆

    Science.gov (United States)

    Pignataro, Gustavo Soriano; Junqueira, André Elias; Matsunaga, Fabio Teruo; Matsumoto, Marcelo Hide; Belloti, João Carlos; Tamaoki, Marcel Jun Sugawara

    2015-01-01

    Objective To evaluate the reproducibility of the AO/Asif classification for humeral shaft fractures. Methods Consecutive radiographs of the arm in both anteroposterior and lateral view from 60 patients with humeral shaft fractures were analyzed. Six observers who were familiar with the AO/Asif classification (three shoulder and elbow surgery specialists and three general orthopedists) were selected to make the analysis, which was done at three different times. The data were subjected to statistical analysis using the kappa coefficient. Results The intra and interobserver concordance was statistically significant in all the analyses. Conclusions All the evaluators showed concordance between the three evaluations that was considered to be statistically significant. However, the highest values were found among the specialists. PMID:26417565

  13. O apoio dos pais ao desenvolvimento da carreira de atletas masculinos de basquetebol

    Directory of Open Access Journals (Sweden)

    Cleiton Pereira Reis

    2016-06-01

    Full Text Available Resumo O estudo verificou se o apoio oriundo dos pais aos atletas profissionais é diferente em relação aos atletas da categoria sub-19 anos de Minas Gerais durante a categoria de base. Comparou-se também tal apoio de acordo com as fases de desenvolvimento. Buscou-se a opinião dos treinadores da categoria sub-19 de MG sobre tal assunto. Participaram do estudo atletas profissionais e da categoria sub-19 de MG, além de treinadores mineiros. Os pais financiavam a carreira dos filhos em ambos os grupos, porém poucos frequentavam os jogos e treinamentos. Os pais dos atletas mineiros preferem que os filhos abandonem o esporte para estudar ou trabalhar, já que na opinião deles a profissão de jogador de basquetebol muitas vezes não é um caminho viável.

  14. The CfAO's Astronomy Course in COSMOS: Curriculum Design, Rationale, and Application

    CERN Document Server

    Cooksey, Kathy L; Porter, Jason; Raschke, Lynne; Severson, Scott; Hinkley, Sasha

    2010-01-01

    From 2001 to 2007, COSMOS provided a teaching and outreach venue for the Center for Adaptive Optics Professional Development Program (CfAO PDP). COSMOS is a four-week residential mathematics and science summer program for high-school students organized by the University of California on four of its campuses. Two topical science courses comprised each COSMOS cluster. An astronomy course has always formed a basis for the CfAO PDP-affiliated cluster. The course included a variety of pedagogical techniques to address a diversity of learners and goals. We outline the astronomy course---lectures, activities, etc.---and provide the rationale for what was taught, how it was aught, and when it was taught.

  15. Tamanho de amostras para quantificação da podridão-mole da alface e da couve-chinesa Sample size for assessment of soft rot in lettuce and Chinese cabbage

    Directory of Open Access Journals (Sweden)

    Adriano Márcio Freire Silva

    2008-02-01

    Full Text Available Os cultivos de alface e couve-chinesa podem ter a produção reduzida devido à ocorrência da podridão-mole, causada por Pectobacterium carotovorum subsp. carotovorum. O objetivo deste estudo foi determinar os tamanhos ideais das amostras para quantificação da incidência dessa doença em levantamentos no campo. Foram realizadas amostragens da incidência da podridão-mole em oito áreas de plantio de alface e cinco de couve-chinesa, situadas nos principais municípios produtores do Estado de Pernambuco. Considerando os resultados obtidos e um erro aceitável de 20%, em futuros levantamentos da incidência da podridão-mole em alface recomenda-se a amostragem de 32 parcelas de 4,5 m²/ha e 20 plantas/parcela, enquanto em couve-chinesa a amostragem de 22 parcelas de 10,5 m²/ha e 20 plantas/parcela. Para ambas as culturas não houve correlação significativa (P=0,05 entre os níveis de incidência da doença e os tamanhos das amostras.Lettuce and Chinese cabbage may present yield reduction due to the occurrence of soft rot caused by Pectobacterium carotovorum subsp. carotovorum. This study aimed to determine the ideal sample size for assessing disease incidence in field surveys. Samples of soft rot incidence were conducted in eight lettuce growing areas and five Chinese cabbage growing areas, located in the main production cities around Pernambuco State. Considering 20% of acceptable error, the results pointed out that future surveys of the soft rot incidence on lettuce should analyze 32 plots with 4.5 m²/ha and 20 plants/plot, while for Chinese cabbage the sample should include 32 plots with 10.5 m²/ha and 20 plants/plot. No significant correlation (P=0.05 was found between disease incidence levels and sample sizes for both crops.

  16. 以甲状腺功能亢进为首发表现的葡萄胎1例%A case of complete hydatidiform mole presenting as hyperthyroidism

    Institute of Scientific and Technical Information of China (English)

    王仁忠; 易树萍

    2013-01-01

    葡萄胎(HM)是一种异常的人类妊娠,可将其分为完全性葡萄胎(CHM)和部分性葡萄胎(PHM)。其主要临床表现为停经后阴道不规则流血、子宫异常增大、妊娠呕吐、腹痛、卵巢黄素化囊肿及甲状腺功能亢进征象等,其中甲状腺功能亢进临床表现少见。我们报道1例以间断性怕热、多汗、心悸、消瘦为主要临床表现的育龄期女性患者,常规抗甲状腺药物治疗无效,后经阴道B超、血HCG检查诊为CHM。清宫术后患者临床症状好转,甲状腺功能完全恢复正常,从而证实甲状腺功能亢进继发于CHM。因此,临床医生对于育龄期女性甲状腺功能亢进患者,在排除甲状腺性、垂体性以及医源性因素后,应注意葡萄胎及其他妊娠滋养细胞疾病等妇科情况及疾病。%Hydatidiform mole(HM) is an abnormal human pregnancy, and can be divided into complete hydatidiform mole(CHM) and partial hydatidiform mole(PHM).Its main clinical manifestations are postmenopausal vaginal irregular bleeding, abnormal enlargement of uterine, hyperemesis gravidarum, development of theca lutein ovarian cysts and hyperthyroidism,et al, of which hyperthyroidism is uncommon. Here we reported a childbearing age female patient presenting as fear heat, hidrosis, palpitation, marasmus, but conventional treatment of anti-thyroid drugs was ineffective, and finally diagnosed of CHM through the scan of transvaginal ultrasound B and serum human chorionic gonadotropin(HCG).After curettage, the clinical symptoms of the patient improved and the thyroid function returned to normal, confirming hyperthyroidism was secondary to CHM. HM and the other gestational trophoblastic disease should be considered in all childbearing age female patients with hyperthyroidism and no evidence of thyroid, pituitary and iatrogenic factors.

  17. Complete mole in a dichorionic twin pregnancy after intracytoplasmic sperm injection Mola hidatiforme completa em gravidez bicoriônica após injecção intracitoplasmática de espermatozoides

    Directory of Open Access Journals (Sweden)

    Tiago José Santos de Matos Ferraz

    2013-01-01

    Full Text Available A dichorionic twin pregnancy with complete hydatidiform mole and coexistent fetus is a rare and challenging situation, whose pathogenesis has not been yet fully understood. We present a case of a 39-year-old woman who underwent intracytoplasmic sperm injection with two embryos transfer. The 12-week gestation ultrasound examination revealed normal fetus and placenta with features of hydatidiform mole, leading to pregnancy termination. Autopsy and histological examinations diagnosed a complete mole coexisting with a normal fetus, and the genetic analysis showed a diploid fetus with biparental genome and molar tissue with paternal diploidy. This case highlighted that complete molar pregnancies may still occur even though pregnancy is achieved after intracytoplasmic sperm injection. A review of the literature was performed by collecting data from the few similar reported cases and by commenting on the pathogenesis of this rare condition.Uma gravidez bicoriônica com mola hidatiforme completa e feto normal é uma situação rara e desafiadora, cuja patogênese não foi ainda totalmente compreendida. Apresenta-se o caso de uma mulher de 39 anos submetida à injeção intracitoplasmática de espermatozoides com transferência de dois embriões. Na ecografia pré-natal realizada na 12ª semana de gestação, foi identificado um embrião morfologicamente normal e uma placenta com características molares. Esta situação resultou na terminação eletiva da gravidez. A autópsia e o estudo histológico permitiram o diagnóstico definitivo de uma mola hidatiforme completa coexistindo com feto normal. A análise genética mostrou feto diploide com genoma biparental e tecido molar com diploidia paterna. Este caso ressaltou que as gestações com mola hidatiforme completa poderão ainda ocorrer, mesmo que a gravidez seja realizada após uma injeção intracitoplasmática de espermatozoides. Foram realizadas uma revisão dos raros casos descritos na literatura

  18. Avaliação da sensibilidade da goiabeira 'Pedro Sato' ao ozônio

    Directory of Open Access Journals (Sweden)

    Regina Maria de Moraes

    2011-09-01

    Full Text Available O objetivo deste trabalho foi avaliar a sensibilidade da goiabeira 'Pedro Sato' ao ozônio (O3, em comparação à cultivar Paluma, descrita como sensível. Oito plantas de cada cultivar foram submetidas separadamente a ar filtrado e a ar filtrado + O3, cinco horas por dia, durante quatro dias. Foram avaliadas fotossíntese (Asat, injúrias foliares visíveis e concentração de antocianinas e taninos. Plantas das duas cultivares também foram expostas, durante três meses, a condições ambientais em local contaminado por O3, tendo-se avaliado fotossíntese, injúrias foliares e crescimento. Plantas fumigadas com O3 apresentaram redução de Asat e da atividade fotoquímica, além de manifestação de injúrias foliares. 'Paluma' apresentou maior redução de Asat, injúrias foliares mais severas e redução de taninos. Quando exposta ao ambiente contaminado, 'Paluma' apresentou trocas gasosas mais altas, mas apresentou redução de Asat 30 dias antes que 'Pedro Sato'. O crescimento não foi afetado em 'Pedro Sato', cujas injúrias foliares tiveram menor incidência, severidade e precocidade do que em 'Paluma'. A menor taxa de crescimento de 'Paluma' indica maior sensibilidade ao O3. Apesar de responder com menor intensidade ao estresse induzido pelo O3, a cultivar Pedro Sato não pode ser considerada tolerante, pois apresenta danos fotoquímicos, injúrias foliares e alterações nos conteúdos de metabólitos secundários quando exposta a esse poluente.

  19. Development and Study on Nitrogen Removal Controller in A/O Process

    Institute of Scientific and Technical Information of China (English)

    MA Yong; PENG Yong-zhen; WANG Shu-ying

    2004-01-01

    In this paper three controllers for A/O process are developed, including a DO cascade controller, an external carbon flow rate controller and an internal recycling flow rate controller. The objective of the different controllers is to control the nitrate and ammonia concentration. Simulation study demonstrated that these controllers could efficiently control nitrogen removal and meet stricter effluent quality standards at a minimum cost.

  20. Subordinate but proud: Curaçao's free blacks and mulattoes in the eighteenth century

    Directory of Open Access Journals (Sweden)

    Wim Klooster

    1994-07-01

    Full Text Available Focuses on the socio-economic position of free non-whites in 18th-c. Curaçao. The manumission rate was relatively high and consequently a large group of free non-whites was created. Blacks and mulattoes enjoyed religious freedom as well as considerable economic freedom. Their growing numbers and social and economic assertiveness alarmed the whites, who gradually admitted the most successful mulattoes in their circles.

  1. Do corpo histérico ao "corpus" teórico

    Directory of Open Access Journals (Sweden)

    Francisco Ramos de Farias

    1992-09-01

    Full Text Available Este estudo aborda a maneira pela qual Freud, de forma original, efetuou uma leitura no corpo-sintoma da histérica e construiu uma clínica inédita destinada ao tratamento das neuroses. Esta clínica, fundada na transferência, é suportada pelo edifício teórico que tem o inconsciente e a sexualidade como paradigmas.

  2. Análise de fatores associados ao significado do trabalho

    Directory of Open Access Journals (Sweden)

    Sergio Hideo Kubo

    2012-12-01

    Full Text Available O trabalho tem sido visto não somente como forma de obter a renda, mas também como atividade que proporciona realização pessoal, status social e possibilidade de estabelecer e manter contatos interpessoais, entre outros. Nesta pesquisa, teve-se como objetivo investigar os fatores que influenciam e conferem sentido ao trabalho, como centralidade do trabalho, normas da sociedade e objetivos e resultados valorizados. Na centralidade do trabalho, procurou-se investigar o grau de importância do trabalho dentro do contexto das diversas áreas da vida das pessoas, como família, lazer, religião e vida comunitária. Em normas da sociedade, foram analisados os pontos mais significativos no tocante ao que a sociedade deveria proporcionar ao indivíduo, assim como o que o indivíduo deveria fazer em prol da sociedade. Nos objetivos e resultados valorizados, foi pesquisado o que as pessoas buscam com o trabalho. A partir da pesquisa na literatura, foi elaborado um modelo inicial que, não se mostrando satisfatório segundo critérios estatísticos, foi substituído por outro que apresentou significância estatística e boa aderência aos dados. O modelo escolhido foi o que melhor goodness-of-fit apresentou, quando se utilizou modelagem de equações estruturais pelo método partial least square. O estudo revelou que o significado do trabalho se reflete, na ordem, na centralidade do trabalho, nos objetivos e resultados valorizados e, por último, nas normas sociais.

  3. Study of power source transfer time criteria for Ling'Ao NPP phase II

    International Nuclear Information System (INIS)

    The solution for source transfer time beyond criteria problem in LingAo project II is introduced in the paper. System is modified and criteria are updated. Analysis and tests are performed to get proper parameter. International rules are used to evaluate the new criteria. The problem is solved finally, contributing stable power supply to unit pre-peration, start-up and operation. Experience also gathered for CPR1000 new projects. (author)

  4. Do valor intrínseco e de sua aplicabilidade ao meio ambiente

    Directory of Open Access Journals (Sweden)

    Tânia Ap. Kuhnen

    2004-01-01

    Full Text Available O tema deste estudo é a teoria do valor sagrado da vida e sua aplicabilidade às questões de ética prática, mais especificamente ao meio ambiente. O objetivo geral consiste em apontar os limites da concepção de Dworkin sobre a teoria do sagrado, quando aplicada ao meio ambiente, e a solução que Singer oferece para a atribuição de valor ao mesmo. Justifica-se esse trabalho em decorrência da importância de se discutir, a partir da análise dessas teorias filosóficas, questões vinculadas ao estabelecimento de um princípio ético que, além de englobar, no campo da ação moral, todos os seres sencientes, envolva também o meio ambiente como um todo. Além disso, o tema que aqui se desenvolve é uma contribuição do raciocínio filosófico-teórico para a discussão de problemas relevantes no campo da ética prática. Esse estudo ainda se justifica por abordar a questão da linha moral divisória entre os seres que são ou não incluídos na comunidade moral, o que representa outro problema que concerne à ética. As diferentes formas de classificação não foram capazes de incluir todos os seres vivos no âmbito da comunidade moral. Há sempre exclusões, as quais tendem a diminuir com o surgimento de teorias éticas inovadoras, dentre elas as que serão abordadas a seguir.

  5. Diversity and spatial heterogeneity of mangrove associated sponges of Curaçao and Aruba

    OpenAIRE

    Hunting, E.R.; Van, Soest; Geest, van der, A.H.M.; A. DE VOS; Debrot, A.O.

    2008-01-01

    Sponges are major epibionts of mangrove roots in the Caribbean. Mangrove sponge communities in the Caribbean mainly consist of species that are typical to this habitat and community compositions often differ from those found on coral reefs nearby. Heterogeneity in species distributions between locations and within locations between roots is often reported. This study quantifi es the diversity and abundance of mangrove associated sponges in the inner bays of Curaçao and Aruba and correlates va...

  6. Transtorno afetivo bipolar: perfil farmacoterapêutico e adesão ao medicamento

    Directory of Open Access Journals (Sweden)

    Adriana Inocenti Miasso

    2012-06-01

    Full Text Available Este estudo teve como objetivos verificar a adesão de portadores de transtorno afetivo bipolar (TAB à terapêutica medicamentosa e identificar possíveis causas de adesão e não adesão ao medicamento de acordo com o perfil farmacoterapêutico. Trata-se de estudo transversal, descritivo, realizado em Núcleo de Saúde Mental de um município do interior paulista. Participaram do estudo 101 pacientes com TAB. Para coleta dos dados, utilizou-se a entrevista estruturada e o teste de Morisky-Green e, para a análise dos mesmos, o programa Statistical Package for the Social Science. Os resultados mostraram que a maioria (63% dos sujeitos investigados não adere ao medicamento. Apesar de não ter ocorrido diferenças significativas entre o grupo de aderentes e não aderentes, para as variáveis investigadas, foi possível verificar a utilização de polifarmacoterapia e regimes terapêuticos complexos no tratamento do TAB. Permanece como desafio a implementação de estratégias que possam melhorar, na prática, a adesão de pacientes ao tratamento medicamentoso.

  7. From Daya Bay to Ling Ao. The benefits of a duplication policy

    International Nuclear Information System (INIS)

    Over the past 15 years, the People's Republic of China has experienced very rapid economic growth of annual average 8%, which must be supported by fast expanding energy production, notably of electricity. China has the considerable amount of coal resources, but most of these resources are located in the north of the country, and the vast hydroelectric potential in Southwestern China is difficult to develop. Therefore, in the coastal provinces of Southeast China, where economic expansion is greatest, nuclear power has been chosen to meet the need. The Qinshan No. 1 PWR with 300 MWe output is the first Chinese nuclear power facility, and started the operation in 1992. Two 985 MWe PWRs have been operated since 1994 at Daya Bay. The construction of Qinshan No. 2 and 3 PWRs of 600 MWe each are in progress, and are expected to start the operation in 2001. These plants were designed by China based on the Framatome technology. Two more 985 MWe plants will be constructed on Ling Ao site, and operated in 2002 and 2003. The main milestones of Framatome collaboration with Chinese partners are explained. The Daya Bay nuclear power station and the Ling Ao project are reported. The benefits of duplicating the Daya Bay nuclear power station at Ling Ao are summarized. The M310 PWR plants of 985 MWe are the modern, proven type backed by more than reactor-years of operating experience. (K.I.)

  8. Teor de metionina + cistina para codornas de corte do nascimento aos 21 dias de idade

    Directory of Open Access Journals (Sweden)

    T.Z.B. Vidal

    2015-02-01

    Full Text Available Estudou-se o efeito do teor de metionina + cistina sobre o desempenho de codornas de corte durante a fase inicial (nascimento ao 21° dia. Foram utilizadas 360 codornas, de ambos os sexos, distribuídas em delineamento experimental inteiramente ao acaso. Os tratamentos consistiram em seis níveis de metionina + cistina total (0,86; 0,96; 1,06; 1,16; 1,26 e 1,36, quatro repetições e 15 aves por unidade experimental. As características avaliadas foram o peso corporal, ganho de peso, consumo e conversão alimentar para fase inicial. Observou-se efeito quadrático significativo do teor de metionina + cistina sobre todas as variáveis avaliadas do nascimento ao 21° dia de idade, sendo observado melhor desempenho nas codornas alimentadas com 1,21% de metionina + cistina para peso corporal e ganho de peso, 1,36% de metionina + cistina para consumo e 1,1% de metionina + cistina para conversão alimentar. A exigência de metionina + cistina para máximo ganho de peso na fase inicial é de 1,21%.

  9. Ausência de expectativa de suporte para o cuidado aos idosos da comunidade

    Directory of Open Access Journals (Sweden)

    Déborah Cristina de Oliveira

    2016-06-01

    Full Text Available RESUMO Objetivo: identificar fatores associados à ausência de expectativa de suporte para o cuidado aos idosos da comunidade. Método: foram utilizados parte dos dados do estudo multicêntrico "Fragilidade em Idosos Brasileiros", pesquisa quantitativa, epidemiológica e transversal desenvolvida no período de 2008 a 2009. Foram realizadas análises de comparação e regressão dos dados de 671 idosos. Resultados: a avaliação da expectativa de suporte para o cuidado aos idosos mostrou-se um bom indicador de risco para ausência de expectativa de suporte em mulheres, idosos que residiam sozinhos e com percepção ruim da própria saúde. Conclusão: conclui-se que é preciso refletir sobre o sistema de suporte oferecido aos idosos no Brasil, visto que o perfil destes que estão em risco é cada vez maior na população. Ressalta-se também a importância da inserção de métodos subjetivos para avaliação da percepção dos idosos sobre suporte para o cuidado.

  10. Currículo universitário: do México ao Brasil neoliberais

    Directory of Open Access Journals (Sweden)

    Dostoiewski Mariatt de Oliveira Champangnatte

    2016-03-01

    Full Text Available Resumo O objetivo deste estudo foi discutir e comparar percepções e ações curriculares de professores universitários mexicanos e brasileiros. Contextualizando as realidades socioeconômicas dos dois países e, principalmente, as políticas governamentais voltadas ao ensino superior, observa-se, nas várias falas dos professores, uma abordagem simplista de currículo, significando-o apenas como preocupações de conteúdos administrados em disciplinas e planos de ensino. Aspectos da realidade social, política e econômica são desatrelados do pensamento e prática curriculares, onde o maior objetivo se tornou a adequação ao mercado de trabalho. Nota-se, direta e indiretamente, influências do pensamento e práticas neoliberais no posicionamento desses professores tanto quanto ao currículo como com a própria funcionalidade do ensino superior, refletindo e reproduzindo, em seus discursos e práticas, as políticas governamentais neoliberais vigentes.

  11. Profilaxia das úlceras associadas ao estresse Prophylaxis of ulcers associated with stress

    Directory of Open Access Journals (Sweden)

    Carlos Eduardo Pompilio

    2010-06-01

    Full Text Available INTRODUÇÃO: As úlceras da mucosa gastroduodenal que aparecem após graves insultos têm sido chamadas de úlceras associadas ao estresse ou, mais genericamente, de "doença mucosa associada ao estresse" (DMAE. São conhecidas desde a Antiguidade e apesar de relacionarem-se com altos índices de morbidade e mortalidade, esquemas de profilaxia no intuito de minimizar seus riscos, só foram introduzidos recentemente. Os inibidores da bomba de prótons têm desempenhado papel importante nesse cenário. MÉTODOS: O presente artigo é uma breve revisão sobre seu uso dentro do contexto clínico da profilaxia do sangramento gastrointestinal relacionado ao estresse.INTRODUCTION: Gastroduodenal mucosal ulcers that appear after severe insults have been called ulcers associated with stress or, more generally, "mucosal disease associated with stress" (DMAE. Are known since antiquity and although linked with high morbidity and mortality, prevention schemes in order to minimize their risk, were introduced only recently. The proton pump inhibitors have played an important role in this scenario. METHODS: This article is a brief review of its use within the clinical context of prophylaxis of gastrointestinal bleeding due to stress.

  12. O enfermeiro frente ao desmame precoce na consulta de enfermagem à criança

    Directory of Open Access Journals (Sweden)

    Caroline Aparecida Coutinho Monteschio

    2015-10-01

    Full Text Available RESUMOObjetivo:analisar a atuação do enfermeiro frente ao desmame precoce em crianças menores de 6 meses de idade.Método:estudo descritivo de abordagem qualitativa. Participaram do estudo enfermeiros que realizavam consulta de enfermagem à criança de maneira programática em unidades de saúde da família em Cuiabá-MT. Os dados foram coletados nos meses de janeiro e fevereiro de 2012, por meio da observação participante da consulta de enfermagem. Para análise dos dados foi utilizada a análise de conteúdo.Resultados:os enfermeiros, na maioria das vezes, utilizaram estratégias apropriadas para o manejo dos problemas mais comuns na amamentação, apesar de algumas condutas não terem, ainda, evidência científica comprovada, quanto aos benefícios e/ou prejuízos à sua prática.Conclusão:os enfermeiros abordaram aspectos importantes do aleitamento materno durante as consultas e trabalharam em prol da promoção e do resgate ao aleitamento materno exclusivo.

  13. Simultaneous Nitrogen and Phosphorus Removal by Denitrifying Dephosphatation in a (AO)2 Sequencing Batch Reactor

    Institute of Scientific and Technical Information of China (English)

    ZHANG Yan-ping; PENG Yong-zhen; WANG Shu-ying; WANG Shao-po

    2005-01-01

    A 24 L working volume reactor was used for the research on simultaneous phosphorus (P) and nitrogen (N) removal by denitrifying dephosphatation in an anaerobic-oxid-anoxic-oxid sequencing batch reactor ((AO)2SBR) system. The durations of each phase are: anaerobic 1.5 h, aerobic 2.5 h, anoxic 1.5 h, post-aerobic 0.5 h, settling 1.0 h, fill 0.5 h. The successful removal of nitrogen and phosphorus is achieved in a stable (AO)2SBR. The effluent P concentrations is below 1 mg/L, and the COD,TN and P average removal efficiency is 88.9%, 77.5% and 88.7%, respectively. The batch experiment results show that the durations of aerobic and anoxic phase influence the P removal efficiency. Some feature points are found on the DO, ORP and pH curves to demonstrate the complete of phosphate release and phosphate uptake. These feature points can be used for the control of (AO)2 SBR.

  14. O DUALISMO DO SER ÓRFICO NA EPÍSTOLA DE PAULO AOS ROMANOS

    Directory of Open Access Journals (Sweden)

    Roger Ribeiro da Silva

    2010-01-01

    Full Text Available Este trabalho consiste na comparação de fragmentos de textos encontrados na obra de Platão e na Epístola aos Romanos atribuída à Paulo. Retirados de inúmeros textos atribuídos a Platão, estes fragmentos tiveram confirmados indícios da teologia órfica pelo professor Alberto Bernabé Pajares. E ao aplicar a Metodologia de Analise do Discurso Teológico, desenvolvido especificamente para este trabalho, e comparado os resultados individuais, encontramos pontos de encontro entre as duas teologias, a Órfica e a Paulina, acentuando o que tange a crença no Dualismo do Ser. A problemática levantada neste trabalho se refere a como a representação1 da alma unida ao corpo, encontrada em escritos paulinistas, apresenta indícios de contatos com fundamentos órficos no berço do cristianismo.

  15. Physical Growth and Nutritional Status among Ao Naga Children of Nagaland, Northeast India

    Directory of Open Access Journals (Sweden)

    Temsumongla Longkumer

    2013-01-01

    Full Text Available The present study was carried out on 571 Ao Naga children including 289 boys and 282 girls aged 8 to 15 years from Mokokchung town, Nagaland. This study tried to find out the physical growth according to the height and weight and nutritional status according to the body mass index (BMI following the classification by Cole et al. Our study revealed that the girls were taller than boys till 13 years and the boys became taller thereafter. As for weight, the girls were heavier during 10 to 14 years. The mean height and weight increased as the age advanced in both boys and girls. The prevalence of underweight was 30.12% and the prevalence of overweight was 2.28% among the Ao Naga children, and the girls were found to have a higher prevalence of overweight and the boys had a higher prevalence of underweight. This revealed that both underweight and overweight coexisted among the Ao Naga children from Mokokchung town, although the prevalence of overweight was not high.

  16. Riscos e doenças ocupacionais relacionados ao exercício da anestesiologia

    Directory of Open Access Journals (Sweden)

    Daniel Volquind

    2013-04-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: O exercício da anestesiologia não é isento de riscos para o anestesiologista. Considerada um local de trabalho insalubre em razão dos riscos potenciais que oferece, a sala de operações (SO é o local no qual o anestesiologista passa a maior parte do tempo. Nesta revisão, propomos uma análise dos riscos ocupacionais aos quais estão expostos os anestesiologistas em sua prática diária. CONTEÚDO: Apresentamos a classificação dos riscos e suas relações com as doenças ocupacionais. CONCLUSÃO: O controle dos riscos ocupacionais, aos quais os anestesiologistas são expostos diariamente, se faz necessário para o desenvolvimento de um local de trabalho adequado e com riscos reduzidos para a boa prática da anestesiologia. Isso contribui para a diminuição do absenteísmo, a melhora da assistência prestada ao paciente e da qualidade de vida do anestesiologista.

  17. Escala de atitudes face ao lazer em adolescentes e jovens adultos

    Directory of Open Access Journals (Sweden)

    Teresa Freire

    2007-04-01

    Full Text Available Atualmente, o lazer e as atitudes face ao lazer têm sido alvo de interesse na investigação psicológica, concretamente no domínio da Psicologia Social. O objetivo do presente estudo foi adaptar a escala Leisure Attitude Scale de Raghb e Beard, construída para avaliar as atitudes face ao lazer em função das três componentes de atitude (cognitiva, afetiva e comportamental para a população de estudantes, adolescentes e jovens adultos portugueses. Participaram no estudo 462 sujeitos (57,8% do sexo feminino e 42,2% do sexo masculino, com uma média de idades de 19,97 (desvio padrão de 4,85. Os resultados obtidos confirmam a estrutura e as características psicométricas da versão original, refletindo valores largamente aceitáveis de fidelidade (consistência interna e validade (validade de conteúdo quer para a escala total quer para as várias sub-escalas (cognitiva, afetiva e comportamental. Conclui-se pela adequação da escala na medida das atitudes face ao lazer, no contexto português.

  18. Would be the photon a composed particle? / Sobre a possibilidade da quantiza\\c{c}\\~ao dos fluxos de campo na radia\\c{c}\\~ao eletromagn\\'etica

    CERN Document Server

    Duarte, Celso de Araujo

    2013-01-01

    Here it is made a comparative analysis between the classical and the quantum expressions for the energy of electromagnetic radiation (ER). The comparison points to the possibility of the quantization of the magnetic and the electric field fluxes in the ER. ----- Apresenta-se uma an\\'alise comparativa entre as express\\~oes cl\\'assica e qu\\^antica para a energia da radia\\c{c}\\~ao eletromagn\\'etica (RE). A compara\\c{c}\\~ao nos aponta para a possibilidade de haver uma quantiza\\c{c}\\~ao dos fluxos dos campos magn\\'etico e el\\'etrico na RE.

  19. Adaptive Optics at Optical Wavelengths: Test Observations of Kyoto 3DII Connected to Subaru Telescope AO188

    Science.gov (United States)

    Matsubayashi, K.; Sugai, H.; Shimono, A.; Akita, A.; Hattori, T.; Hayano, Y.; Minowa, Y.; Takeyama, N.

    2016-09-01

    Adaptive optics (AO) enables us to observe objects with high spatial resolution, which is important in most astrophysical observations. Most AO systems are operational at near-infrared wavelengths but not in the optical range, because optical observations require a much higher performance to obtain the same Strehl ratio as near-infrared observations. Therefore, to enable AO-assisted observations at optical wavelengths, we connected the Kyoto Tridimensional Spectrograph II (Kyoto 3DII), which can perform integral field spectroscopy, to the second generation AO system of the Subaru Telescope (AO188). We developed a new beam-splitter that reflects light below 594 nm for the wavefront sensors of AO188 and transmits above 644 nm for Kyoto 3DII. We also developed a Kyoto 3DII mount at the Nasmyth focus of the Subaru Telescope. In test observations, the spatial resolution of the combined AO188–Kyoto 3DII was higher than that in natural seeing conditions, even at 6500 Å. The full width at half maximum of an undersampled (1.5 spaxels) bright guide star (7.0 mag in the V-band) was 0.″12.

  20. Adaptive Optics at Optical Wavelengths: Test Observations of Kyoto 3DII Connected to Subaru Telescope AO188

    Science.gov (United States)

    Matsubayashi, K.; Sugai, H.; Shimono, A.; Akita, A.; Hattori, T.; Hayano, Y.; Minowa, Y.; Takeyama, N.

    2016-09-01

    Adaptive optics (AO) enables us to observe objects with high spatial resolution, which is important in most astrophysical observations. Most AO systems are operational at near-infrared wavelengths but not in the optical range, because optical observations require a much higher performance to obtain the same Strehl ratio as near-infrared observations. Therefore, to enable AO-assisted observations at optical wavelengths, we connected the Kyoto Tridimensional Spectrograph II (Kyoto 3DII), which can perform integral field spectroscopy, to the second generation AO system of the Subaru Telescope (AO188). We developed a new beam-splitter that reflects light below 594 nm for the wavefront sensors of AO188 and transmits above 644 nm for Kyoto 3DII. We also developed a Kyoto 3DII mount at the Nasmyth focus of the Subaru Telescope. In test observations, the spatial resolution of the combined AO188-Kyoto 3DII was higher than that in natural seeing conditions, even at 6500 Å. The full width at half maximum of an undersampled (1.5 spaxels) bright guide star (7.0 mag in the V-band) was 0.″12.

  1. Óleos essenciais e extratos vegetais no controle da podridão mole em alface crespa Essential oils and plant extracts on the control of soft rot of crispy lettuce

    OpenAIRE

    Cristiane L Silva; Souza, Elineide B; Kátia CS Felix; Alice MG Santos; Márcia V Silva; Rosa de LR Mariano

    2012-01-01

    Avaliou-se o efeito de óleos essenciais e extratos vegetais no controle da podridão mole em alface, bem como, a influência desses produtos nas características físico-químicas desta hortaliça. Nos testes in vitro, discos de papel de filtro foram embebidos em 11 óleos essenciais e 20 extratos vegetais nas concentrações 0,0; 0,25; 0,50; 0,75 e 1% e 0,0; 10, 40, 70 e 100%, respectivamente, e depositados sobre meio de cultura contendo Pectobacterium carotovorum subsp. carotovorum (Pcc A1). Os halo...

  2. Podridão-mole em pós-colheita de batata (Solanum tuberosum) incitada por Pseudomonas viridiflava Post hervest soft rot in potabo (Solanum tuberosum) induced by Pseudomonas viridiflava

    OpenAIRE

    Dirceu Macagnan; Reginaldo da Silva Romeiro; Davi Mesquita de Macedo; Daniel Augusto Schurt

    2007-01-01

    Isolou-se uma bactéria incitadora de podridão-mole em batata e procurou-se identificá-la em nível de espécie. Testes biológicos, bioquímicos e tintoriais permitiram posicionar o microrganismo em questão com pertencente à espécie Pseudomonas viridiflava. Procurou-se também investigar a suscetibilidade de diferentes órgãos de reserva de distintas espécies botânicas à espécie bacteriana. Este trabalho mostra e confirma que outras espécies que não as de Pectobacterium spp. são capazes de incitar ...

  3. Non-ideality of methanol solution's of artificial serum in the mole fraction range from 5 x 10(-4) to 5 x 10(-3) at 25 degrees C

    DEFF Research Database (Denmark)

    Ralloff, K.P.G.; Westh, Peter; Purssell, R.A.;

    2003-01-01

    ), on the other hand, produced the osmotic coefficient significantly larger than unity in serum solutions studied. This is consistent with the findings by the earlier freezing point depression study on ethanol in human blood serum solutions. The partial molar enthalpy data indicated highly non-ideal behaviours......Vapour pressure and excess partial molar enthalpy were measured at 25 degreesC for solutions of methanol in H2O and artificial serum solutions. The mole fraction range studied was from 5 x 10(-4) to 5 x 10(-3). From the vapour pressure data, the partial pressures were determined by the Barker......'s and Boissonnas' methods. Various thermodynamic functions were then calculated from them. The curve-fitting (Barker's method) gave the osmotic coefficients very close to unity in all the cases, including serum solutions. The purely numerical method without resorting to any fitting function (Boissonnas' method...

  4. Expressao genica associada ao estresse oxidativo no coracao de camundongo apos isquemia intestinal

    Directory of Open Access Journals (Sweden)

    Frederico Somaio Neto

    2014-03-01

    Full Text Available FUNDAMENTO: O fenômeno da isquemia e reperfusão intestinal é um evento frequente na clínica e está associado a repercussões deletérias em órgãos a distância, em especial ao coração. OBJETIVO: Investigar a expressão gênica do estresse oxidativo e defesa antioxidante no coração de camundongos isogênicos, submetidos a isquemia e reperfusão intestinal (IR. MÉTODOS: Doze camundongos (C57BL/6 foram distribuídos em dois grupos: Grupo IR (GIR com 60 min de oclusão da artéria mesentérica superior, seguidos de 60 min de reperfusão. Grupo Controle (GC submetidos a anestesia e a laparotomia sem o procedimento de IR observados por 120 min. As amostras de intestino e coração foram processadas pelo método (RT-qPCR / Reverse transcriptase - quantitative Polymerase Chain Reaction para determinar a expressão gênica de 84 genes relacionados ao estresse oxidativo ("t" de Student, p < 0,05. RESULTADOS: Observou-se no tecido intestinal (GIR uma expressão significantemente aumentada em 65 (74,71% genes em relação ao tecido normal (GC, e 37 (44,04% genes estiveram hiperexpressos (maior que três vezes o limiar permitido pelo algoritmo. No tocante aos efeitos da I/R intestinal a distância no tecido cardíaco verificou-se a expressão significantemente aumentada de 28 genes (33,33%, mas somente oito genes (9,52% se hiperexpressaram três vezes acima do limiar. Quatro (7,14% desses oito genes se expressaram simultaneamente nos tecidos intestinal e cardíaco. No GIR notaram-se cardiomiócitos com núcleos de menor tamanho, picnóticos, ricos em heterocromatina e raros nucléolos, indicando sofrimento cardíaco. CONCLUSÃO: A I/R intestinal promoveu a hiperexpressão estatisticamente significante de oito genes associados ao estresse oxidativo a distância no tecido miocárdico.

  5. Adaptação e adaptação cruzada de Listeria monocytogenes aos compostos eugenol e carvacrol

    OpenAIRE

    E. R. N. SOUZA; V. M. R. TEBALDI; R.H. Piccoli

    2015-01-01

    RESUMOA evolução de certos microrganismos permite sua rápida adaptação aos ambientes em constante mudança, desenvolvendo assim, tolerância ou resistência ao aumento de determinados estresses. O uso de compostos bioativos provenientes da flora nativa tem sido apontado como uma possível solução para os problemas de controle da resistência e proliferação bacteriana. Este trabalho visou verificar a adaptação e adaptação cruzada de L. monocytogenes, frente aos compostos fenólicos eugenol e carvacr...

  6. Medicina moderna: rumo à prevenção, à cura, ao bem-estar e à longevidade

    OpenAIRE

    Ajai Singh

    2010-01-01

    A medicina moderna tem realizado muitas coisas nos campos de doenças infecciosas e de emergências para assistir a cura. Na maior parte dos outros campos, ela visa, sobretudo, ao controle, que é outro nome para o tratamento paliativo. A farmacologia, na qual se inclui a psicofarmacologia, é igualmente dirigida ao controle e ao alívio. Está na hora de profissionais da área e pesquisadores voltarem-se decisivamente para a prevenção e para a cura. Ademais, o outro grande desafio da medicina moder...

  7. Personalidade, resiliência e atitudes face ao envelhecimento em idosos do meio urbano e meio rural

    OpenAIRE

    Pinto, Ana Sofia Rodrigues

    2015-01-01

    Tese de mestrado, Psicologia (Secção de Psicologia Clínica e da Saúde, Núcleo de Psicologia Clínica Dinâmica), Universidade de Lisboa, Faculdade de Psicologia, 2015 A presente investigação refere-se ao estudo da personalidade, resiliência e atitudes face ao envelhecimento, numa amostra de indivíduos idosos. Os objetivos são: (1) analisar a influência do meio ecológico na resiliência e nas atitudes face ao envelhecimento; (2) analisar a relação da personalidade com a resiliência e ...

  8. A dimensão ética do cuidado de enfermagem ao idoso hospitalizado na perspectiva de enfermeiros

    OpenAIRE

    Aline Branco Amorim de Almeida; Maria Geralda Gomes Aguiar

    2011-01-01

    Estudo descritivo de abordagem qualitativa, realizado com oito enfermeiros de um hospital público, por meio de entrevistasemi-estruturada, objetivou compreender como estes percebem a dimensão ética do cuidado ao idoso. Os dados foram analisados conforme o método de análise de conteúdo e organizados nas categorias: Valores éticos no cuidado ao idoso e Problemas éticos no cuidado ao idoso. Revelou-se que os enfermeiros percebem a importância dos valores, principalmente o respeito e a responsabi...

  9. AVALIAÇÃO DE DUAS METODOLOGIAS DE EXPANSÃO AO FORNO DO POLVILHO AZEDO

    Directory of Open Access Journals (Sweden)

    MAEDA Kelly C.

    2001-01-01

    Full Text Available Duas metodologias de expansão ao forno foram comparadas em 52 amostras de polvilho azedo de três Estados: Santa Catarina, Paraná e Minas Gerais. Os resultados obtidos permitiram visualizar uma proposta de classificação em nível nacional da expansão ao forno do polvilho azedo. No método instrumental foi usado o Farinógrafo Brabender para estabelecer uma massa de consistência padrão de 60UF e no método prático, a consistência semelhante da massa foi determinada de forma empírica. Com a metodologia instrumental obteve-se biscoitos com expansão superior à metodologia prática, mas maior coeficiente de variação, o que pode ser devido a maior sensibilidade do método. Ambas as metodologias poderão ter aplicação, dependendo da finalidade. A metodologia instrumental, pelo custo do equipamento, é mais adequada para laboratórios, desde que se utilize maior número de repetições, para reduzir o coeficiente de variação. Ambas as metodologias ensaiadas permitiram classificar as amostras com o mesmo perfil de desempenho. As amostras provenientes do Estado do Paraná apresentaram as maiores expansões ao forno quando comparados com os outros Estados. Pela metodologia prática a expansão média das amostras do Estado do Paraná foi de 14,1mL/g. As amostras do Estado de Minas Gerais apresentaram as menores expansões ao forno, em média de 13,3mL/g. Foi proposta neste artigo uma classificação para avaliar a qualidade do polvilho azedo, complementando a legislação brasileira que não estabelece este índice para o produto. Quanto à propriedade de expansão ao forno, as amostras avaliadas podem ser divididas em 3 tipos A, B e C. No tipo A (10% amostras de polvilhos azedo são classificadas como qualidade extra, no tipo B (80% os polvilhos são de média qualidade e o tipo C (10% de qualidade inferior. Os resultados obtidos pela metodologia prática permitiram estabelecer como tipo A o polvilho azedo que apresenta um índice de

  10. Cyberbullying – do diagnóstico de necesidades à construçao de um manual de formaçao.

    Directory of Open Access Journals (Sweden)

    Teressa Pessoa

    2011-01-01

    Full Text Available O impacto do cyberbullying na sociedade e junto das crianças e jovens, tão mais complexo quanto mais sofisticadas as ferramentas tecnológicas disponíveis, tem chamado a atenção para a importância, a nível internacional, da definição de estratégias de prevenção e intervenção junto de potenciais agentes educativos, isto é, para o desenvolvimento de uma proposta, com dimensão europeia, de Cyber- Training.Neste trabalho após uma breve apresentação do projectoCyberTraining: A Researchbased Training Manual On Cyberbullying1 dar-se-á a conhecer o processo de desenvolvimento de um manual de formação baseado numa investigação a nível europeu suportada na plataforma Moodle e, nesta, pela ferramenta Fórum. Através de uma análise de necesidades junto de formadores e do estudo, junto de especialistas, do estado de arte no domínio a nível de diferentes países, é mostrado todo um percurso inovador de construção colaborativa de conhecimento relativamente ao conceito cyberbullying assim como relativamente ao desenvolvimento de práticas de formação ou cybertraining.----------------------------------------------------------------The impact of the cyberbullying on society and among children and young people, revealed as ever more complex as more sophisticated technological tools becomeavailable, has called attention to the importance, at the international level, of a definition of strategies for prevention and intervention among potential educational agents, i.e. to develop a proposal for Cyber-Training, with a European dimension.In this paper, after a brief presentation of the European project CyberTraining: A Researchbased Training Manual on Cyberbullying, an account will be given of the process of developing a training manual based on research at European level supported in the Moodle platform, and within this, by the Forum tool. By means of a needs analysis among trainers and analysis by experts of the state of the art in

  11. Disciplina partidária e apoio ao governo no bicameralismo brasileiro

    Directory of Open Access Journals (Sweden)

    Pedro Robson Pereira Neiva

    2011-06-01

    Full Text Available O artigo avalia a disciplina dos partidos políticos no poder Legislativo brasileiro e o apoio que proporcionam ao governo, sob uma perspectiva bicameral. Busco dois objetivos principais. O primeiro é o de incluir o Senado na discussão sobre o relacionamento entre o poder Executivo e o poder Legislativo no país, comparando-o com a Câmara dos Deputados. Em segundo lugar, procuro avaliar os partidos individualmente, levando em consideração as suas características peculiares, que não são inerentes ao sistema partidário. A análise foi feita a partir das votações nominais realizadas na Câmara dos Deputados e no Senado Federal no período de 1989 a 2008, comparando o comportamento dos partidos entre si e com eles mesmos, ao longo do tempo. A abordagem cross-section e longitudinal permitiu observar resultados até então não identificados pela literatura que trata do relacionamento entre o poder Executivo e o poder Legislativo no país. Apesar de reforçar a corrente da literatura que afirma serem os partidos coesos, disciplinados e previsíveis, argumento que eles diferem substancialmente entre si, seja em suas estratégias, seja em sua forma de articulação. Dada a elevada fragmentação e as características peculiares de cada um dos partidos, não parece apropriado falar-se em atributos sistêmicos, que se estendam para todos eles; menos ainda quando se leva em consideração as duas casas legislativas.

  12. Adesão ao tratamento no transtorno bipolar Compliance to treatment in bipolar disorder

    Directory of Open Access Journals (Sweden)

    Aida Santin

    2005-01-01

    Full Text Available O transtorno bipolar (TB é uma doença crônica, recorrente, presente em 1,5% da população, estando associada a altas taxas de mortalidade e prejuízos socioeconômicos. O lítio, a carbamazepina e o ácido valpróico são os estabilizadores de humor mais usados. Em tratamentos prolongados, como é o caso do TB, a má-adesão dos pacientes é uma das maiores dificuldades. Verifica-se que fatores ligados ao paciente, aos medicamentos e aos médicos possam ser responsáveis pela baixa adesão. A psicoeducação, a terapia cognitivo-comportamental e a terapia focada na família são estratégias propostas para o aumento da adesão.Bipolar disorder (BD is a chronic and recurrent illness that occurs in 1,5% of the population. This illness is associated with high rates of mortality and social/economic burden. Lithium, carbamazepine and valproic acid are the most used mood stabilizers. In long term treatments, as in BD, one of the main difficulties is the patient's adherence. It appears that factors associated to the patient, drug and the physician are responsible for the low adherence. The use of psycho-education, cognitive-behavioral therapy and focused family therapy have been put forward as a means to increase adherence.

  13. Gastrite hemorrágica por alergia ao leite de vaca: relato de dois casos

    Directory of Open Access Journals (Sweden)

    Machado Rodrigo Strehl

    2003-01-01

    Full Text Available OBJETIVO: descrever dois lactentes com gastrite hemorrágica, devido à alergia ao leite de vaca. DESCRIÇÃO DOS CASOS: ambos os pacientes apresentavam hematêmese, vômitos e desnutrição. Os pacientes apresentavam infiltrado eosinofílico em mucosa gástrica biopsiada e resolução dos sintomas após o início de dieta com exclusão da proteína do leite de vaca. COMENTÁRIOS: gastrite hemorrágica devido à alergia ao leite de vaca é um diagnóstico incomum. Até o momento foram relatados 10 pacientes com gastrite alérgica, e as principais manifestações clínicas são vômitos, desnutrição, anemia e hematêmese. A gastrite por alergia ao leite de vaca pode apresentar-se em diferentes graus de gravidade, e pode ser subdiagnosticada em muitos pacientes. A menos que o tratamento correto seja iniciado, o paciente desenvolverá desnutrição protéico-calórica grave e anemia. Doença alérgica do trato gastrointestinal superior deve ser considerada em todos os lactentes com vômitos recorrentes, particularmente se complicado com hematêmese. O diagnóstico de gastrite alérgica é clínico, auxiliado pela endoscopia e anatomia patológica.

  14. Treatment of AO/OTA 31-A3 intertrochanteric femoral fractures with a percutaneous compression plate

    Directory of Open Access Journals (Sweden)

    Fei Luo

    2014-01-01

    Full Text Available OBJECTIVE: AO/OTA 31-A3 intertrochanteric femoral fractures have completely different fracture line directions and biomechanical characteristics compared with other types of intertrochanteric fractures. The choice of the fixation method has been a focus of dispute among orthopedic trauma surgeons. The purpose of this study was to review the outcomes of these fractures treated with a percutaneous compression plate at our institute. METHOD: Seventeen patients with AO/OTA 31-A3 intertrochanteric femoral fractures were treated with a percutaneous compression plate at our institute from January 2010 to December 2011. The clinical data and imaging results were retrospectively analyzed. RESULTS: The medical complication of popliteal vein thrombosis occurred in one patient. Sixteen patients were followed up for 12 to 21 months. Two patients had malunion and mild pain. Fracture collapse occurred in two patients, with one having head penetration. These two patients had moderate pain. There were no occurrences of nonunion or reoperation. The mean Harris hip score obtained during the last follow-up was 84.1 (61-97. Patients with a poor quality of reduction were more likely to have pain results (p = 0.001. A trend existed toward the presence of a poor quality of reduction (p = 0.05 in patients with a collapse of fracture. Patients with poor preoperative mobility were more likely to have a lower Harris hip score (p = 0.000. CONCLUSION: The percutaneous compression plate is an alternative device for the treatment of AO/OTA 31-A3 intertrochanteric femoral fractures. Good fracture reduction and an ideal placement position of the neck screw are important in the success of the device.

  15. Custeio baseado em atividades (ABC) aplicado aos processos de compra e venda de distribuidora de mercadorias

    OpenAIRE

    Rodney Wernke

    2005-01-01

    Trata-se de estudo de caso sobre a aplicação do Custeio Baseado em Atividades (ABC) efetuada em empresa que atua na distribuição de mercadorias. O estudo teve por objetivo identificar o efetivo consumo de recursos destinados aos processos de compra e de venda pelos três principais segmentos de mercado em que a entidade atua, no sentido de melhorar sua análise de rentabilidade. Após efetuar uma revisão da literatura sobre os principais aspectos do ABC, descreve-se o estudo efetuado. Inicialmen...

  16. Avaliação da eficiencia do combate aos incendios florestais no Brasil

    OpenAIRE

    Lima, Gumercindo Souza

    2013-01-01

    Este trabalho teve como objetivo avaliar a eficiência do combate aos incêndios florestais no Brasil, com base em dados levantados no perlodo de 3.984 a 3.937. A eficiência do combate foi determinada baseada em três parimetros principais: a área queimada, avaliando a eFiciência em termos da dlstribuição dos incêndios ocorridos em diferentes classes de tamanho e observando a média da área queimada por Incêndio; o tempo para o ataque, em que se avaliou a mobilização dos combatentes, distribuindo...

  17. Ilha das Flores, estatura e peso em crianças dos 6 aos 11 anos.

    OpenAIRE

    Antunes, Maria A. G.

    1990-01-01

    IV Expedição Científica do Departamento de Biologia – Flores 1989. 0s estudos de crescimento físico humano têm-se revelado de grande interesse pois permitem conhecer as características de diferentes populações e a variabilidade existente intra e interpopulações. Mas um dos aspectos mais importantes destes estudos talvez o de, ao se analisar o estado de crescimento e tempo de desenvolvimento do indivíduo, permitir destrinçar factores que influenciam nefastamente o crescimento. ...

  18. VSOP monitoring of the compact BL Lac object AO 0235+164

    CERN Document Server

    Frey, S; Gabuzda, D C; Salter, C J; Altschüler, D R; Perillat, P; Aller, M F; Aller, H D; Hirabayashi, H; Davis, M M

    2005-01-01

    In 1999, the highly compact and variable BL Lac object AO 0235+164 was identified as the highest brightness temperature active galactic nucleus observed with the VLBI Space Observatory Programme (VSOP), with T_B > 5.8 x 10^{13} K. The sub-milliarcsecond radio structure of this source has been studied with dual-frequency (1.6 and 5 GHz), polarization-sensitive VSOP observations during 2001 and 2002. Here we present the results of this monitoring campaign. At the time of these observations, the source was weakly polarized and characterized by a radio core that is clearly resolved on space-ground baselines.

  19. Patologia da tiróide associada ao consumo de amiodarona

    OpenAIRE

    Lopes, Zita Maria Teixeira Castro

    2013-01-01

    A amiodarona é um antiarrítmico rico em iodo, usado no tratamento de taquiarritmias, com efeitos adversos muitas vezes subvalorizados, entre os quais se destacam as alterações sobre a tiroide. Apesar de a maioria dos pacientes permanecer eutiroideia, a amiodarona interfere no metabolismo das hormonas da tiroide, por mecanismos intrínsecos ao próprio fármaco ou pelo seu alto conteúdo em iodo. Quando clinicamente evidente, esta disfunção da tiroide iatrogénica pode manifestar-se como hipotiroid...

  20. Diferenças entre adolescentes do sexo feminino e masculino na vulnerabilidade individual ao HIV

    OpenAIRE

    Renata Holanda Dutra dos Anjos; José Augusto de Souza Silva; Luciane Ferreira do Val; Laura Alarcon Rincon; Lucia Yasuko Izumi Nichiata

    2012-01-01

    O objetivo deste estudo foi analisar comparativamente a vulnerabilidade ao HIV/AIDS de homens e mulheres adolescentes, baseada em seus conhecimentos, valores e práticas. Trata-se de um estudo exploratório-descritivo com abordagem quantitativa. Os estudantes responderam a um questionário do qual foram selecionadas questões relevantes para análise. Totalizaram 207 adolescentes, sendo 43,5% do sexo masculino e 56,5% do feminino. A maior parte dos adolescentes declara já ter tido sua primeira rel...

  1. Atitudes face ao uso de Preservativo Masculino em contexto de Festa Académica

    OpenAIRE

    Frias, Ana; Sim-Sim, Margarida; Pontes, Ana; Palminhas, Edgar; Caldeira, Ermelinda; Casas Novas, Vitória

    2014-01-01

    Introdução: O percurso académico, além do ensino formal, possui momentos significativos pelo simbolismo de alguns eventos. A Receção aos Caloiros, representa a entrada num compartimento específico do saber e a Queima das Fitas, o atingir de competências para exercer uma Arte. Valorizadas por uns e menosprezadas por outros (Frias, 2003) a Praxe e as respetivas festividades levam a excessos, a alcoolização. Aumenta-se assim a probabilidade de sexo desprotegido e a exposição a Infeções Sexualmen...

  2. Fatores associados ao uso inconsistente do preservativo entre pessoas vivendo com HIV/Aids

    OpenAIRE

    Renata Karina Reis; Elizabete Santos Melo; Elucir Gir

    2016-01-01

    RESUMO Objetivo: analisar a prevalencia e fatores associados ao uso inconsistente do preservativo masculino entre pessoas vivendo com o HIV/Aids (PVHA). Método: estudo transversal realizado em serviços de atendimento especializados (SAE), com 228 PVHA. Realizou-se análise multivariada com modelo de regressão logística. Resultados: 143 participantes preencheram os critérios de inclusão e a prevalência do uso inconsistente do preservativo foi de 28,7%. Observou-se maior adesão entre os homen...

  3. Psicologia vocacional e feminismo crítico : do passado ao futuro

    OpenAIRE

    Saavedra, Luísa

    2013-01-01

    Durante algumas décadas a teoria e investigação vocacional caracterizaram-se por uma preocupação central com os homens brancos, de classe média e com as características individuais, guiada por pressupostos positivistas. Ao mesmo tempo, o aconselhamento focou-se fundamentalmente em mudanças de foro individual. Contudo, a intensificação da globalização, bem como o movimento pós-moderno, com as suas críticas à ciência, provocaram consideráveis mudanças nessas concetualizações. Ce...

  4. A FUNÇÃO SOCIAL DO DIREITO AUTORAL E O ACESSO AO CONHECIMENTO

    OpenAIRE

    Alexandre Azis Pereira Filho; Oseias Amaral; Naila Fernanda Sbsczk Pereira Meneguetti

    2014-01-01

    O presente estudo aborda o tema da função social do direito autoral e o acesso ao conhecimento em face do caráter individualista dos direito autorais.  Discute inicialmente o direito de propriedade a fim de apresentar o conceito de função social da propriedade. Analisa historicamente a evolução do direito de propriedade e o surgimento da ideia de função social. Busca enquadrar o direito autoral como um ramo do direito de propriedade, especificamente, a propriedade intelectual. Apresenta e dis...

  5. Localização de páginas web do conceito ao processo

    OpenAIRE

    Céu, Susana Maria Nogueira do

    2009-01-01

    Conceitos como Globalização, Internacionalização, Localização e Tradução surgem, na realidade da indústria da língua, com uma grande interligação, mas com perspectivas nem sempre concordantes. O nosso trabalho analisa, por isso, as diferentes definições propostas dedicando especial atenção ao conceito de localização, uma vez que o nosso projecto analisa o processo de localização de uma página Web desenvolvido num contexto empresarial real. O nosso enfoque recai mais específi...

  6. Organizadores e cortadores de comprimidos: riscos e restrições ao uso

    OpenAIRE

    Caroline Ribeiro de Borja-Oliveira

    2013-01-01

    Com base em análise documental, foram discutidas e problematizadas as limitações associadas à utilização de organizadores e cortadores de comprimidos, como questão de saúde pública. Os organizadores destinados ao armazenamento e transporte de comprimidos e cápsulas expõem essas formas farmacêuticas a fatores ambientais dos quais estariam protegidos em suas embalagens originais, comprometendo sua estabilidade, eficácia e segurança. Os cortadores oferecem risco adicional quanto a perda da eficá...

  7. Prevalência e fatores de risco relacionados ao uso de drogas entre escolares

    Directory of Open Access Journals (Sweden)

    José Baus

    2002-02-01

    Full Text Available OBJETIVO: Analisar a prevalência e os fatores de risco relacionados ao uso indevido de drogas entre estudantes de uma escola pública de primeiro e segundo graus. MÉTODOS: Foi realizado estudo descritivo transversal, utilizando, como instrumento de pesquisa, um questionário anônimo, padronizado e amplamente testado no Brasil para levantamento do uso de drogas. A população estudada foi constituída de 478 estudantes de escola pública de primeiro e segundo graus, de Florianópolis, SC. Os questionários foram aplicados por estudantes universitários devidamente treinados. Entre os estudantes pesquisados, 43% e 32% foram de faixa etária de 13 a 15 anos e de 16 a 18 anos, respectivamente, com predomínio de classes socioeconômicas mais altas. RESULTADOS: A prevalência de uso de maconha na vida (19,9%, solventes (18,2%, anfetamínicos (8,4% e álcool (86,8% foi elevada em Florianópolis, comparada a outras capitais da região Sul e à média brasileira. Notou-se elevado e freqüente uso (seis ou mais vezes por mês de álcool (24,2%, maconha (4,9%, solventes (2,5% e anfetamínicos (2,3%. Os fatores demográficos relacionados ao uso de drogas na vida foram idade, sexo, classe socioeconômica e vida junto aos pais. A chance de garotas usarem remédios para emagrecer ou ficarem acordadas foi o dobro da chance de garotos e, quanto ao uso de tranqüilizantes, quase o triplo. Os garotos tinham um risco quase duas vezes maior de uso de solvente do que as garotas. A classe socioeconômica alta foi associada a um risco duas vezes maior do uso de álcool do que a classe baixa. O risco de uso de cigarro e maconha na vida foi 84% e 67% maior, respectivamente, para alunos cujos pais estavam separados. CONCLUSÃO: Constatou-se alta prevalência de uso de várias drogas entre os alunos de primeiro e segundo graus.

  8. Implementação de corredores verdes aplicado ao turismo sustentável

    OpenAIRE

    Pinho, Juliana Sofia Silva

    2012-01-01

    Este trabalho surge no âmbito na necessidade de estudar e de aliar o desenvolvimento do turismo à conservação da natureza e ao desenvolvimento de mecanismos de prevenção e preservação da natureza e dos habitats. O objetivo principal deste trabalho foi o estudo da possibilidade de implementação de uma rede de corredores verdes que promovam o turismo sustentável na zona da Ria de Aveiro. A metodologia usada para este trabalho passou pela identificação dos principais pontos de interesse tu...

  9. Neuropatia Periférica Familiar por Susceptibilidade ao Entrapment (Neuropatia Tomaculosa)

    OpenAIRE

    Pinto Viana, J; Coimbra, J.; Goulart, Z; Bigotte de Almeida, L; Cabral Beirão, J

    1991-01-01

    Os autores apresentam um caso de neuropatia periférica familiar por susceptibilidade ao entrapment e comparam-no com os descritos na literatura. As principais características desta neuropatia são: hereditariedade autossómica dominante, mononeuropatias recorrentes de localização variável (cubital, mediano, ciático poplíteo, externo, plexo braquial) e aspectos morfológicos característicos na biópsia do nervo. O nervo sensitivo revela alterações predominantes desmielinizantes, com espessamentos ...

  10. Uso de suplementos para acasalamento de bezerras Angus aos 14 meses de idade

    OpenAIRE

    M.B. Alves; M.G. Rocha; L. Pötter; S.C.B. Stivanin; V.S. Hampel; Á.M. Fonseca Neto; M.J.O Sichonany; P.H. Moterle

    2016-01-01

    RESUMO O experimento foi conduzido com o objetivo de avaliar o desenvolvimento de novilhas de corte em três sistemas alimentares: exclusivamente em pastagem de azevém (Lolium multiflorum Lam.) ou em pastagem de azevém e recebendo 0,93% do peso corporal de grão de milho inteiro ou grão de aveia branca como suplemento. O delineamento experimental foi o inteiramente ao acaso, com medidas repetidas no tempo. A utilização da pastagem de azevém, com ou sem uso de grão de milho ou aveia como supleme...

  11. AVALIAÇÃO DA SUSCETIBILIDADE DA KLEBSIELLA PNEUMONIAE AOS BETALACTÂMICOS

    Directory of Open Access Journals (Sweden)

    Isabelle Carvalho Coelho

    2015-08-01

    Full Text Available Justificativa e objetivos: A Klebsiellapneumoniae é um bacilo Gram negativo causador de infecções relacionadas à assistência à saúde. Nos últimos anos, tem se tornando um microrganismo multirresistente, em virtude da produção de enzimas beta-lactamases de espectro estendido e carbapenemases. O estudo teve como objetivos avaliar o perfil de suscetibilidade da K. pneumoniae em relação acarbapenêmicos; identificar produção de carbapenemases e determinar o perfil de suscetibilidade das cepas bacterianas em relação a outros β-lactâmicos. Métodos: Pesquisa com caráter experimental com abordagem quantiqualitativa. Utilizou-se 27 isolados, oriundos de diferentes espécimes clínicos de pacientes com vários tipos de infecção. Os testes de suscetibilidade aos beta-lactâmicos foram realizados pelo método de disco-difusão, seguindo o parâmetro de Kirby-Bauer. Nos testes de suscetibilidade foramutilizados discos de antibióticos, amoxicilina-clavulanato, cefoxitina, cefotaxima, ceftazidima, cefepime, imipenem, meropenem e ertapenem. Para a detecção de carbapenemase, mediante a utilização do teste de Hodge modificado foram utilizados os antibióticos meropenem, e ertapenem. Resultados: Entre ascepas de K. pneumoniae, utilizadas na pesquisa, 59,3% apresentaram suscetibilidade e 40,7% foram resistentes aos beta-lactâmicos, pertencentes ao grupo carbapenêmicos. Não foramidentificadas cepas produtoras de carbapenemases. 18,5% das cepas de K. pneumoniaeforam identificadas como produtoras de β-lactamase de espectro estendido. Conclusão: Com base nos resultados obtidos, a resistência que 18,5% das cepas de K. pneumoniae apresentaram em relação aos β-lactâmicosfoi em função da produção de β-lactamases de espectro estendido, haja visto, que o teste de identificação para essas enzimas foi realizado. Sugere-se mais pesquisas na identificação de cepas produtoras de carbapenemases, dado a grande ocorrência desses

  12. Algoritmos genéticos aplicados ao planejamento do transporte principal de madeira

    OpenAIRE

    Souza, Darlon Orlanmunder de

    2013-01-01

    Nas empresas florestais em que a madeira pode ser destinada para mais do que uma fábrica, o planejamento da colheita pode influenciar significativamente no fluxo de madeira e, consequentemente, nos custos de transporte. O planejamento da colheita envolve as decisões de quais pontos de produção cortar, quando cortar e quais equipes atuam em cada ponto de produção. O objetivo deste trabalho foi desenvolver um modelo de algoritmo genético (método heurístico), que permita aos tomadores de decisõe...

  13. Percepção dos receptores sanguíneos quanto ao processo transfusional

    OpenAIRE

    Maritza Margareth Faquetti; Raquel Luzia Rosa; Maria Lígia dos Reis Bellaguarda; Daniele Delacanal Lazzari; Adriana Dutra Tholl; Cladis Loren Kiefer Moraes

    2014-01-01

    Pesquisa qualitativa, exploratória descritiva, que objetivou conhecer a percepção dos receptores sanguíneos quanto ao processo transfusional. A pesquisa foi realizada em uma unidade de hemoterapia de um município da região sul do Brasil e os dados foram analisados por meio do Discurso do Sujeito Coletivo. Foram entrevistados, por meio de instrumento semiestruturado, onze pacientes, homens e mulheres entre 30 e 95 anos, em recuperação pós-cirúrgica de cirurgia cardíaca, submetidos à transfusão...

  14. Novas abordagens terapêuticas no combate ao Envelhecimento Cutâneo

    OpenAIRE

    Santos, Joana Loureiro Marques dos

    2011-01-01

    Trabalho apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências Farmacêuticas. O envelhecimento cutâneo é um processo complexo e multifatorial, que resulta em alterações funcionais e estéticas da pele. Os avanços na biologia da pele têm aumentado a compreensão da homeostasia deste órgão, assim como do seu processo de envelhecimento, levando ao desenvolvimento de tratamentos e técnicas com a finalidade de prevenir este mecanismo e de...

  15. Suscetibilidade do capim-colonião e de cultivares de milho ao flúor

    Directory of Open Access Journals (Sweden)

    Rimena Ramos Domingues

    2011-01-01

    Full Text Available A emissão de fluoretos à atmosfera oriunda da produção de superfosfatos e de cerâmica tem causado preocupação pelo efeito tóxico às plantas, contudo são poucos os estudos desenvolvidos acerca do problema com espécie de interesse econômico agrícola. Desenvolveu-se o estudo para avaliar o efeito do flúor (F atmosférico em plantas de capim-colonião e de cultivares de milho, utilizando como referência espécies bioindicadoras do tipo sensível e tolerante. As plantas foram expostas à contaminação pelo F atmosférico por curtos períodos durante 32 dias em sistema de nebulização com 0,16 mol L-1 de ácido fluorídrico no ambiente interno de uma câmara (~0,20 mmol m-3 de F, havendo um controle não exposto, com quatro repetições. A exposição das plantas ao F causou aumento da concentração do elemento nas folhas até 60 mg kg-1 para o capim-colonião, e entre 100 mg kg-1 nas folhas novas e 170 mg kg-1 nas folhas velhas para quatro cultivares de milho, o que demonstrou o efeito cumulativo do elemento no ambiente. Sintomas visuais da toxicidade foram observados nas plantas e se caracterizaram pela ocorrência de cloroses e necroses na lâmina foliar. O capim-colonião é uma espécie bastante sensível ao poluente no ar. As cultivares de milho DKB 390 e Ômega 8315 também são mais sensíveis ao F quando comparadas às AG7088 e 2B707. Os teores de clorofila a nas plantas foram mais afetados pelo F em relação aos teores de clorofila b.

  16. Seguimento farmacoterapêutico direcionado aos animais domésticos: seria viável?

    OpenAIRE

    Maria Aparecida NICOLETTI; André Rinaldi FUKUSHIMA

    2014-01-01

    A atuação global na área da saúde humana tem direcionado seu foco ao cuidado do paciente, tendo o medicamento como segundo plano. Neste sentido, em humanos o seguimento farmacoterapêutico (que faz parte da Atenção Farmacêutica) vem sendo uma ferramenta de grande auxílio para a detecção de Problemas Relacionados a Medicamentos (PRM) para que possam ser evitados ou identificados visando impedir/minimizar o aparecimento de Resultados Negativos relacionados a Medicamentos (RNM). Consi...

  17. Dual AO/EB Staining to Detect Apoptosis in Osteosarcoma Cells Compared with Flow Cytometry

    OpenAIRE

    Liu, Kuan; Liu, Peng-Cheng; Liu, Run; Wu, Xing

    2015-01-01

    Background The aim of this study was to evaluate the ability of dual acridine orange/ethidium bromide (AO/EB) staining to detect tumor cell apoptosis. According to apoptosis-associated changes of cell membranes during the process of apoptosis, a clear distinction is made between normal cells, early and late apoptotic cells, and necrotic cells. Material/Method We cultured human osteosarcoma cells with 30, 60, and 120 μg/ml kappa-selenocarrageenan. To assess the rates of cell proliferation and ...

  18. Pneumonia em organização secundária ao uso de amiodarona

    Directory of Open Access Journals (Sweden)

    GULMINI LIA AUGUSTA DE SOUZA

    2001-01-01

    Full Text Available A pneumonia em organização secundária ao uso de amiodarona é rara, com apenas oito casos relacionados na literatura. No presente relato uma paciente de 75 anos, com uso cumulativo de 43g, apresentou tosse produtiva, dispnéia progressiva e infiltrados bilaterais na radiografia do tórax. A biópsia transbrônquica confirmou o diagnóstico. Com a retirada da droga houve melhora clínica e funcional.

  19. Translation between the Neer- and the AO/OTA-classification for proximal humeral fractures

    DEFF Research Database (Denmark)

    Brorson, Stig; Eckardt, Henrik; Audigé, Laurent;

    2013-01-01

    conduct prognostic studies, and to obtain consensus on treatment recommendations when concise definitions and a common 'fracture language' are lacking. Thus, we compared both classifications systems using primary data from large clinical studies to assess how thoroughly both systems conveyed clinically......The reporting and interpretation of data from clinical trials of proximal humeral fractures are hampered by the use of two partly incommensurable fracture classification systems: the Neer classification and the AO/OTA classification. It remains difficult to interpret and generalize results, to...

  20. Semi-Supervised Learning Techniques in AO Applications: A Novel Approach To Drift Counteraction

    Science.gov (United States)

    De Vito, S.; Fattoruso, G.; Pardo, M.; Tortorella, F.; Di Francia, G.

    2011-11-01

    In this work we proposed and tested the use of SSL techniques in the AO domain. The SSL characteristics have been exploited to reduce the need for costly supervised samples and the effects of time dependant drift of state-of-the-art statistical learning approaches. For this purpose, an on-field recorded one year long atmospheric pollution dataset has been used. The semi-supervised approach benefitted from the use of updated unlabeled samples, adapting its knowledge to the slowly changing drift effects. We expect that semi-supervised learning can provide significant advantages to the performance of sensor fusion subsystems in artificial olfaction exhibiting an interesting drift counteraction effect.

  1. Eficiência de adubos fosfatados associados ao enxofre elementar na cultura do milho

    OpenAIRE

    Jucenei Fernando Frandoloso; Maria do Carmo Lana; Silvano Fontaniva; Rodrigo Vianei Czycza

    2010-01-01

    A eficiência agronômica dos adubos fosfatados pode ser afetada pelas fontes de fósforo, propriedades do solo, modo de aplicação e espécie vegetal. Com o objetivo de comparar a eficiência do fosfato natural reativo (FNR) e do superfosfato triplo (SFT) associado ao enxofre elementar, aplicados no sulco de plantio na cultura do milho, instalouse um experimento em condições de campo no município de Toledo, Paraná, em um Latossolo Vermelho eutroférrico. O delineamento experimental consistiu de blo...

  2. Os sentidos e significados atribuidos ao saber cultural no currículo

    OpenAIRE

    Iara Aquino Henn

    2010-01-01

    O presente artigo é fruto de uma pesquisa realizada na proposta pedagógica de Educação de Pessoas Jovens e Adultas de uma escola pública no Brasil. Investigamos os sentidos que os jovens e adultos atribuem aos conhecimentos construídos nas suas trajetória de vida e os significados que são produzidos na relação da sua cultura com os outros conhecimentos. A partir das reflexões de autores como Silva (2003), Padilha (2004), Hall (1997, 2003) Arroyo (2001), Fonseca (2002) indicamos três categoria...

  3. Resistência de genótipos de tomateiro ao ácaro rajado

    OpenAIRE

    Maruyama Wilson Itamar; Toscano Luciana Cláudia; Boiça Júnior Arlindo L.; Barbosa José Carlos

    2002-01-01

    Avaliou-se a resistência de genótipos de tomateiro selvagens [Lycopersicon pennellii (LA 716), L. hirsutum var. glabratum (PI 126449, PI 134417), L. hirsutum (PI 127826, PI 127827), L. peruvianum (CGO 6707), L. peruvianum var. dentatum (WYR 2020, LA 111), L. peruvianum var. glandulosum (LA 1113-1, LA 1113-2)] e comerciais [(L. esculentum) Gem Pride, Santa Clara, e híbridos Bruna VFN, Carmem, Fortaleza, Débora Plus VFN] ao ácaro rajado (Tetranychus urticae). O número médio de ovos, fases imatu...

  4. Caquexia muscular associada ao desenvolvimento de cancro da bexiga em ratos machos Wistar

    OpenAIRE

    Andrade, Andreia Patrícia Teixeira

    2016-01-01

    Dissertação de Mestrado em Biologia Clínica e Laboratorial A caquexia muscular associada ao cancro é uma condição paraneoplásica preocupante. Caquexia, etimologicamente significa “mau estado”, é uma síndrome complexa e multifatorial, que se caracteriza pela perda de tecido adiposo e posterior consumo do músculo-esquelético. Sendo o cancro, só por si, uma doença muito grave, quando associado à caquexia a situação complica-se porque a piorar o estado geral dos doentes. Apesar dos mecanism...

  5. Sensibilizando a equipe de enfermagem ao cuidado humanizado em saúde mental mediante oficinas educativas

    OpenAIRE

    Adriano Brischialiari; Mariluci Alves Maftum; Maria Angélica Pagliarini Waidmann; Verônica Azevedo Mazza

    2008-01-01

    Esta pesquisa exploratória e descritiva foi realizada em uma instituição psiquiátrica de internação integral da Região Norte do Paraná no ano de 2005. O objetivo foi de descrever e avaliar o resultado da implementação de oficinas de sensibilização da equipe de enfermagem para um cuidado humanizado ao paciente com transtorno mental. Participaram 21 técnicos e 25 auxiliares de enfermagem. Os dados foram coletados mediante oficinas e, as dinâmicas de grupo foram fundamentadas em referenciais teó...

  6. LDEF (Prelaunch), AO187-02 : Chemical and Isotropic Measurements of Micrometeoroids by Secondary Ion

    Science.gov (United States)

    1984-01-01

    LDEF (Prelaunch), AO187-02 : Chemical and Isotropic Measurements of Micrometeoroids by Secondary Ion Mass Spectrometry, Tray E08 The prelaunch photograph shows one hundred twenty (120) experiment capture cells installed on six support panels that are mounted in LDEF provided experiment trays. A capture cell consist of four polished high purity germanium plates covered with a 2.5um thick Mylar foil coated with 1300 angstroms of tantalum vapor deposited on the backside and 100 angstroms of gold-palladium vapor deposited on the front side. The capture cells are mounted within an aluminum frame on each panel. The fasteners are nonmagnetic stainless steel.

  7. Cuidados ao recém nascido em fototerapia: o conhecimento da equipe de enfermagem

    OpenAIRE

    Nathália Silva Gomes; Jesislei Bonolo do Amaral Teixeira; Elizabeth Barichello

    2010-01-01

    A icterícia é uma das alterações mais frequentes tanto em recém-nascidos a termo quanto em prematuros. A fototerapia é otratamento mais utilizado nestes casos, porém este tratamento pode ocasionar algumas alterações no bebê, as quais devem ser prevenidas e detectadas precocemente pela equipe de enfermagem. O objetivo do estudo foi identificar o conhecimento da equipe de enfermagem acerca dos cuidados ao recém-nascido e complicações relacionadas a fototerapia. Trata-se de um estudo prospectivo...

  8. A crise económica e o acesso ao medicamento

    OpenAIRE

    Aveiro, João Miguel Almeida Moço

    2013-01-01

    O sector farmacêutico atravessa a par da restante economia uma grave crise, limitando o acesso das populações aos melhores cuidados de saúde. Hoje em dia é obrigatório que a indústria seja capaz de demonstrar o real benefício dos seus produtos, considerando tanto o nível terapêutico, como financeiro. Em Portugal existem uma série de factores que hoje em dia dificultam a possibilidade da indústria colocar à disposição das pessoas os melhores medicamentos. O Financiamento Públ...

  9. EFFECTS OF RETINOIC ACID ON PROLIFERATION AND DIFFERENTIATION OF A HUMAN OVARIAN CARCINOMA CELL LINE: 3AO

    Institute of Scientific and Technical Information of China (English)

    Ming-Juan Xu; Ying Cui; Ning Hui; Yu-Jian Liu

    2005-01-01

    Objective To observe the effects ofretinoic acid (RA) on the proliferation and differentiation of a human ovarian carcinoma cell line: 3AO cells.Methods 3AO cell proliferation was evaluated by viable cell count, percentage of cells in each cycle phase were analyzed by flow cytometric analysis, alkaline phosphatase (AKP) activity was determined as described, and CA125 expression was measured by ELISA.Results RA could inhibit the proliferation of 3AO cells accompanied with morphological changes in a dose-dependent manner. Cell cycle analysis indicated that RA inhibition of 3AO cells growth occurred through induction of G1 arrest with a concomitant reduction in the proportion of cells in S phase, AKP activity increased significantly after treatment with RA (0. l μmol/L) for 1-5 days. Dose-response studies revealed that the AKP activity increased to a different extent as a function of RA concentrations. Furthermore, RA could suppress the expression of CA125 tumor marker in 3AO cells.Conclusion RA could markedly inhibit the proliferation and induce the differentiation of 3AO cells.

  10. The Magellan Adaptive Secondary VisAO Camera: Diffraction- Limited Broadband Visible Imaging and 20mas Fiber Array IFS

    CERN Document Server

    Kopon, Derek; Males, Jared R; Gasho, Victor; Follette, Katherine

    2010-01-01

    The Magellan Adaptive Secondary AO system, scheduled for first light in the fall of 2011, will be able to simultaneously perform diffraction limited AO science in both the mid-IR, using the BLINC/MIRAC4 10\\{mu}m camera, and in the visible using our novel VisAO camera. The VisAO camera will be able to operate as either an imager, using a CCD47 with 8.5 mas pixels, or as an IFS, using a custom fiber array at the focal plane with 20 mas elements in its highest resolution mode. In imaging mode, the VisAO camera will have a full suite of filters, coronagraphic focal plane occulting spots, and SDI prism/filters. The imaging mode should provide ~20% mean Strehl diffraction-limited images over the band 0.5-1.0 \\{mu}m. In IFS mode, the VisAO instrument will provide R~1,800 spectra over the band 0.6-1.05 \\{mu}m. Our unprecedented 20 mas spatially resolved visible spectra would be the highest spatial resolution achieved to date, either from the ground or in space. We also present lab results from our recently fabricated...

  11. MOJO: UMA FERRAMENTA PARA INTEGRAR JUÍZES ONLINE AO MOODLE NO APOIO AO ENSINO E APRENDIZAGEM DE PROGRAMAÇÃO

    Directory of Open Access Journals (Sweden)

    José Osvaldo Mesquita Chaves

    2014-09-01

    Full Text Available Este artigo apresenta o MOJO, uma ferramenta que integra o Moodle e os Juízes Online. Os sistemas de Juízes Online são comumente utilizados em maratonas de programação. Eles são famosos pelo seu repositório de questões e avaliação automática de código-fonte. A ideia para esta integração surgiu da exigência de um maior envolvimento do professor de disciplinas de programação, e como uma forma de disponibilizar um maior número de questões para utilização na prática. Normalmente o professor dessas disciplinas fica sobrecarregado pelos processos de elaboração, avaliação e fornecimento de feedback das questões aos alunos. Esta ferramenta visa diminuir esta sobrecarga, por meio da automatização desses processos.

  12. O panorama das Drogas no México: da margem da sociedade ao centro da cultura

    Directory of Open Access Journals (Sweden)

    Diana Palaversich

    2013-12-01

    Full Text Available O artigo destaca o percurso das manifestações culturais ligadas ao tráfico de drogas no México, de um lugar marginal, de subcultura, na sociedade mexicana das décadas de 1970 e 1980, expressas principalmente através dos narcocorridos e do narcocine, para um lugar no mainstream cultural mexicano, desde o início do século 21, com destaque especial para a narcoliteratura. O aumento da violência, provocado pela guerra ao narcotráfico, produz uma proliferação da temática nos meios de comunicação e se reflete em áreas da cultura como as artes plásticas e a literatura, produzindo um novo tipo de expressão artística ou narrativa, que tanto pode ser oportunista e contribuir para a banalização da violência do narcotráfico como ser crítica e narrar o impacto individual e coletivo do tráfico de drogas, narrar a desenfreada e violenta realidade mexicana sem cair no estilo da imprensa marrom, do folclore ou dos lugares comuns dos romances de ação.

  13. QUALIDADE DE GRÃOS DE MILHO SUBMETIDOS AO PROCESSO DE SECA-AERAÇÃO

    Directory of Open Access Journals (Sweden)

    Ivano Alessandro Devilla

    1999-08-01

    Full Text Available RESUMO Com o presente trabalho, objetivou-se a avaliação do processo de seca-aeração na qualidade final de grãos de milho ( Zea mays L. da variedade Pioneer 3041. Amostras de milho foram submetidas ao processo de seca-aeração, com três temperaturas de secagem (45, 55 e 65C e cinco períodos de repouso (0, 4, 8, 12 e 16 h. Ao final do processo, o teor de umidade do produto e a sua qualidade foram avaliados, usando-se os parâmetros susceptibilidade a quebra, danos internos e externos, grãos ardidos e presença de micotoxinas. Conclui-se que, quanto maior a temperatura de secagem e o tempo de repouso, maior também será a redução no teor de umidade final. O processo de seca-aeração reduziu a susceptibilidade à quebra do produto e à percentagem de grãos, com danos internos; entretanto, não influenciou na percentagem de grãos ardidos nem propiciou a produção de micotoxinas.

  14. Crítica ao postulado positivista da psicologia: de Heidegger a Foucault

    Directory of Open Access Journals (Sweden)

    Rômulo Marques dos Santos Ballestê

    2012-12-01

    Full Text Available A objetivação do ser humano, que segue os ideais de precisão das ciências físico-matemáticas, bem como a sua identificação com o fato biológico, orienta o projeto de ciência da psicologia, desde o século XIX. Michel Foucault aponta esta questão como um paradoxo. A redução do ser humano a objeto dado se mostra contrária às considerações de Martin Heidegger ao tratar do problema do Ser. Portanto, partindo das observações desses dois autores, será realizada uma crítica ao modelo positivista de cientificidade adotado no desenvolvimento da ciência psicológica moderna e, para, por fim, problematizar a ética que se supõe necessária nesta questão.

  15. Recusa ao ato na adolescência: uma "reação subjetiva negativa"?

    Directory of Open Access Journals (Sweden)

    Marta Rezende Cardoso

    2011-06-01

    Full Text Available Estuda-se a questão da violência psíquica na adolescência, em certas patologias do ato, em particular as situações clínicas marcadas pelo negativo desse registro: a recusa radical no plano do agir. Isto se vê na morosidade no ingresso na vida adulta, na conduta de retraimento de certos adolescentes que parecem "resistir" à superação da condição adolescente. Apesar da aparente contradição, situa-se o "recurso ao ato" e a "recusa ao agir" no campo das patologias do ato: o ego atua uma defesa extrema em cuja base insiste uma dimensão traumática, de passividade ante a pulsão.Refusal to acting in adolescence: a "negative subjective reaction?". We study the issue of psychological violence in adolescence, in certain pathologies of the act, particularly the clinical situations marked by the negative of that register: the radical refusal to acting. This is manifested in the delay in entering adulthood, in the withdrawal behavior of certain adolescents who seem to "resist" overcoming the adolescent condition. In spite of the apparent contradiction, we place the "resource to the act" and the "refusal to acting" in the clinical field of the pathologies of the act: the ego acts in an extreme defense, which in its basis has the insistence of a traumatic dimension of passiveness in front of the drive.

  16. Do imaginário ao real: mitos e medos acerca do parto normal.

    Directory of Open Access Journals (Sweden)

    Denismar Borges de MIRANDA

    2014-12-01

    Full Text Available Objetivo: conhecer mitos e medos relacionados ao parto normal segundo primigestas ao término da gestação, e a confirmação ou não destes mitos e/ou medos durante o puerpério tardio. Método: trata-se de pesquisa descritiva com abordagem qualitativa utilizando a técnica de entrevista aberta em profundidade e aplicação de questionários em dois momentos distintos: inicialmente na condição de gestante e posteriormente como puérperas. Os dados foram levantados em uma maternidade pública na cidade de Goiânia após aprovação do comitê de ética em pesquisa (0004.0.168.000-08; análise de conteúdo foi estabelecida para identificação das categorias temáticas. Resultados: emergiram três categorias: A chegada de um bebê, O verdadeiro significado do parto normal e Mitos e medos que permeiam o nascimento. Conclusão: a dor foi identificada como principal fator cultural que interfere na escolha pelo tipo de parto em primigestas. E o parto normal esteve associado à desmistificação acerca do nascimento pelas puérperas.

  17. Fatores associados ao aborto induzido entre jovens pobres na cidade de São Paulo, 2007

    Directory of Open Access Journals (Sweden)

    Rebeca de Souza e Silva

    2012-12-01

    Full Text Available Esse artigo investiga fatores associados ao aborto induzido entre jovens residentes numa comunidade pobre da cidade de São Paulo. A amostra foi composta por 102 homens e 99 mulheres de 14 a 25 anos de idade que já haviam iniciado suas vidas sexuais. Usou-se o modelo hierárquico de regressão logística. As variáveis não ter companheiro sexual no momento da entrevista, sexo do entrevistado, idade no momento da entrevista, priorizar morar só e número de gestações compuseram o modelo final. Dar muita importância a morar só quadruplica a chance de ocorrer um aborto. Jovens mais velhos foram menos propensos a se deparar com um aborto, dado que a chance de se optar pelo aborto se reduz 17% para cada incremento de um ano na idade dos jovens. Isso é indicativo de que as gestações ocorreram de forma inesperada, intempestiva, como é praxe nas condutas adolescentes, sendo as maiores candidatas a terminarem em aborto provocado. Evidencia-se, portanto, a necessidade de serem investidos recursos financeiros para obtenção de métodos contraceptivos eficazes e inócuos, destinados ao início da vida sexual.

  18. Prominent Polarized Flares of the Blazars AO 0235+164 and PKS 1510-089

    CERN Document Server

    Sasada, Mahito; Fukazawa, Yasushi; Kawabata, Koji S; Ikejiri, Yuki; Itoh, Ryosuke; Yamanaka, Masayuki; Sakimoto, Kiyoshi; Ohsugi, Takashi; Yoshida, Michitoshi; Sato, Shuji; Kino, Masaru

    2011-01-01

    We report on multi-band photometric and polarimetric observations of the blazars AO 0235+164 and PKS 1510-089. These two blazars were active in 2008 and 2009, respectively. In these active states, prominent short flares were observed in both objects, having amplitudes of >1 mag within 10 d. The $V-J$ color became bluer when the objects were brighter in these flares. On the other hand, the color of PKS 1510-089 exhibited a trend that it became redder when it was brighter, except for its prominent flare. This redder-when-brighter trend can be explained by the strong contribution of thermal emission from an accretion disk. The polarization degree increased at the flares, and reached >25 % at the maxima. We compare these flares in AO 0235+164 and PKS 1510-089 with other short flares which were detected by our monitoring of 41 blazars. Those two flares had one of the largest variation amplitudes in both flux and polarization degree. Furthermore, we found a significant positive correlation between the amplitudes of...

  19. A ação do Baygon (OMS-33 no combate ao Panstrongylus megistus

    Directory of Open Access Journals (Sweden)

    Ítalo A. Sherlock

    1977-06-01

    Full Text Available Durante o ano de 1972 a 1975 o Baygon (OMS-33 2 - isopropoxifenil - N - metil - carbamato foi utilizado no combate ao P. megistus numa pequena área de 200 casas no Estado da Bahia endêmica para a doença de Chagas. Somente na dosagem de 1,6mg/m², em duas aplicações anuais, os resultados foram considerados satisfatórios, Devido ao elevado custo do produto, é considerado que ele não possa ser utilizado em campanhas profiláticas do governo, podendo entretanto ser utilizado por fazendeiros de recursos em suas próprias fazendas protegendo-se assim contra a proliferação dos vetores da Doença de Chagas.From 1972 to 1975, 200 dwellings were sprayed with Baygon (OMS-33 2 - isopropoxifenil-N-metil-carbamate, to control Panstrongylus megistus the vector of Trypanosoma cruzi in an endemic Chagas' disease area in the State of Bahia, Brazil. A dose of only 1.6 mg/m² of Baygon sprayed twice a year was considered satisfactory for controlling P. megistus. However, the high cost of Baygon prohibits its use on large scale control programs. Nevertheless, the Authors suggest that Baygon can be useful in eliminatíng vector bugs from individuais houses by those who can afford it.

  20. PATOGENICIDADE DE BEAUVERIA BASSIANA (BALS. VUILL. AO ÁCARO Tetranychus urticae KOCH

    Directory of Open Access Journals (Sweden)

    Tamai Marco Antonio

    1999-01-01

    Full Text Available O estudo da patogenicidade de Beauveria bassiana (Bals. Vuill. ao ácaro Tetranychus urticae Koch foi desenvolvido a 25 ± 2°C, 70 ± 5% UR e 12 horas de fotofase, utilizando-se fêmeas recém-emergidas. Os ácaros foram mantidos durante seis dias em discos de folha de Canavalia ensiformis (L. DC. inoculadas com B. bassiana, isolado 447, nas concentrações: 5x106, 1x107, 5x107, 1x108, 5x108 e 1x109 conídios/ml. Este isolado mostrou-se patogênico a T. urticae, apresentando aumento nos valores das mortalidades acumuladas (total, corrigida e confirmada à medida que a suspensão de conídios se tornou mais concentrada. Nas seis concentrações testadas, os valores de mortalidade corrigida ao sexto dia, foram inferiores a 50%, sendo observada apenas na concentração de 1x109 conídios/ml, mortalidade total superior a 50%.