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Sample records for antiqua andnepal516 evidence

  1. Complete Genome Sequence of Yersinia pestis Strains Antiqua andNepal516: Evidence of Gene Reduction in an Emerging Pathogen

    Energy Technology Data Exchange (ETDEWEB)

    Chain, Patrick S.G.; Hu, Ping; Malfatti, Stephanie A.; Radnedge,Lyndsay; Larimer, Frank; Vergez, Lisa M.; Worsham, Patricia; Chu, May C.; Andersen, Gary L.

    2006-01-16

    Yersinia pestis, the causative agent of bubonic andpneumonicplague, has undergone detailed study at the molecular level. Tofurther investigate the genomic diversity among this group and to helpcharacterize lineages of the plague organism that have no sequencedmembers, we present here the genomes of two isolates of the "classical"Antiqua biovar, strains Antiqua and Nepal516. The genomes of Antiqua andNepal516 are 4.7 Mb and 4.5 Mb and encode 4,138 and 3,956 open readingframes respectively. Though both strains belong to one of the threeclassical biovars, they represent separate lineages defined by recentphylogenetic studies. We compare all five currently sequenced Y. pestisgenomes and the corresponding features in Y. pseudotuberculosis. Thereare strain-specific rearrangements, insertions, deletions, singlenucleotide polymorphisms and a unique distribution of insertionsequences. We found 453 single nucleotide polymorphisms in protein codingregions, which were used to assess evolutionary relationships of these Y.pestis strains. Gene reduction analysis revealed that the gene deletionprocesses are under selective pressure and many of the inactivations areprobably related to the organism s interaction with its host environment.The results presented here clearly demonstrate the differences betweenthe two Antiqua lineages and support the notion that grouping Y. pestisstrains based strictly on the classical definition of biovars (predicatedupon two biochemical assays) does not accurately reflect the phylogeneticrelationships within this species. Comparison of four virulent Y. pestisstrains with the human-avirulent strain 91001 provides further insightinto the genetic basis of virulence to humans.

  2. Identification of odorant-binding protein genes from antennal expressed sequence tags of the onion fly, Delia antiqua.

    Science.gov (United States)

    Mitaka, Hayato; Matsuo, Takashi; Miura, Nami; Ishikawa, Yukio

    2011-03-01

    Insect odorant-binding proteins (OBPs) are thought to play a crucial role in the chemosensation of hydrophobic molecules such as pheromones and host chemicals. The onion fly, Delia antiqua, is a specialist feeder of Allium plants, and utilizes a host odorant n-dipropyl disulfide as a cue for its oviposition. Because n-dipropyl disulfide is a highly hydrophobic compound, some OBPs might be indispensable for perception of it. However, no OBP gene has been identified in D. antiqua. Here, to obtain the DNA sequences of D. antiqua OBPs, we performed an analysis of antennal expressed sequence tags (ESTs). Among 288 EST clones, eight D. antiqua OBP genes were identified for the first time. Phylogenetic analysis revealed that each D. antiqua OBP gene is more closely related to its Drosophila orthologs than to the other D. antiqua OBP genes, suggesting that these OBP genes had emerged before the divergence of Delia and Drosophila species. All of the eight D. antiqua OBPs are expressed not only in the antennae but also in the legs, suggesting additional roles in the taste perception of non-volatile compounds. These findings serve as an important basis for understanding the molecular mechanisms underlying the host adaptations of D. antiqua. PMID:20848218

  3. The Complete Mitochondrial Genome of Delia antiqua and Its Implications in Dipteran Phylogenetics.

    Directory of Open Access Journals (Sweden)

    Nai-Xin Zhang

    Full Text Available Delia antiqua is a major underground agricultural pest widely distributed in Asia, Europe and North America. In this study, we sequenced and annotated the complete mitochondrial genome of this species, which is the first report of complete mitochondrial genome in the family Anthomyiidae. This genome is a double-stranded circular molecule with a length of 16,141 bp and an A+T content of 78.5%. It contains 37 genes (13 protein-coding genes, 22 tRNAs and 2 rRNAs and a non-coding A+T rich region or control region. The mitochondrial genome of Delia antiqua presents a clear bias in nucleotide composition with a positive AT-skew and a negative GC-skew. All of the 13 protein-coding genes use ATN as an initiation codon except for the COI gene that starts with ATCA. Most protein-coding genes have complete termination codons but COII and ND5 that have the incomplete termination codon T. This bias is reflected in both codon usage and amino acid composition. The protein-coding genes in the D. antiqua mitochondrial genome prefer to use the codon UUA (Leu. All of the tRNAs have the typical clover-leaf structure, except for tRNASer(AGN that does not contain the dihydrouridine (DHU arm like in many other insects. There are 7 mismatches with U-U in the tRNAs. The location and structure of the two rRNAs are conservative and stable when compared with other insects. The control region between 12S rRNA and tRNAIle has the highest A+T content of 93.7% in the D. antiqua mitochondrial genome. The control region includes three kinds of special regions, two highly conserved poly-T stretches, a (TAn stretch and several G(AnT structures considered important elements related to replication and transcription. The nucleotide sequences of 13 protein-coding genes are used to construct the phylogenetics of 26 representative Dipteran species. Both maximum likelihood and Bayesian inference analyses suggest a closer relationship of D. antiqua in Anthomyiidae with Calliphoridae

  4. Aspects of gametogenesis and radiation pathology in the onion fly, Hylemya antiqua (Meigen); gametogenesis, pt. 1

    International Nuclear Information System (INIS)

    In the scope of a genetic control research project gametogenesis of the onion fly, Hylemya antiqua (Meigen), is studied as a base for investigations on radiation histopathology of the gonads. Various cytological, histological, electronmicroscopical and autoradiographical methods, including investigation of living male germinal cells, are used. The gross anatomy of the male and female reproductive systems is simple as compared to other insect species. In newly hatched larvae the gonads contain on an average 13 germinal cells. Gonads in larvae which are less than 7 days old cannot be distinguished as being male or female. This distinction becomes possible after the apical cell and the apical somatic tissue respectively is formed in the young gonad. Spermatogenesis is treated in a number of paragraphs dealing with the description and identification of germinal and somatic cell types, the ontogenetic development of the testis, the dynamics of spermatogenesis and aspects comparative spermatogenesis. A proper identification of the testicular cell types is considered to be imperative to any correct experimental approach of spermatogenesis. Morphological descriptions of the various germinal and somatic cell types are given accordingly. Comparison of mainly morphological features of male germinal cell types in a number of insect species, including H. antiqua, indicates possibilities for comparative research of spermatogenesis in various insect species. This could provide a basis for comparative radiobiological or other experimental investigations on insect spermatogenesis. Spermatogenesis and oogenesis share a number of features, which suggests a certain similarity of the processes involved

  5. Light spectrum regulates cell accumulation during daytime in the raphidophyte Chattonella antiqua causing noxious red tides.

    Science.gov (United States)

    Shikata, Tomoyuki; Matsunaga, Shigeru; Kuwahara, Yusuke; Iwahori, Sho; Nishiyama, Yoshitaka

    2016-07-01

    Most marine raphidophyte species cause noxious red tides in temperate coastal areas around the world. It is known that swimming abilities enable raphidophytes to accumulation of cells and to actively acquire light at surface layers and nutrients over a wide depth range. However, it remains unclear how the swimming behavior is affected by environmental conditions, especially light condition. In the present study, we observed the accumulation of the harmful red-tide raphidophyte Chattonella antiqua under various light conditions during the daytime in the laboratory. When exposed to ultraviolet-A/blue light (320-480nm) or red light (640-680nm) from above, cells moved downward. In the case of blue light (455nm), cells started to swim downward after 5-15min of irradiation at a photon flux density≥10μmolm(-2)s(-1). When exposed to monochromatic lights (400-680nm) from the side, cells moved away from the blue light source and then descended, but just moved downward under red light. However, mixing of green/orange light (520-630nm) diminished the effects of blue light. When exposed to a mixture of 30μmolm(-2)s(-1) of blue light (440nm) and ≥6μmolm(-2)s(-1) of yellow light (560nm) from above, cells did not move downward. These results indicate that blue light induces negative phototaxis and ultraviolet-A/blue and red lights induce descending, and green/orange light cancels out their effects in C. antiqua. PMID:27107332

  6. Sterilization Effects of Adult-targeted Baits Containing Insect Growth Regulators on Delia antiqua.

    Science.gov (United States)

    Zhou, Fangyuan; Zhu, Guodong; Zhao, Haipeng; Wang, Zheng; Xue, Ming; Li, Xianxian; Xu, Huaqiang; Ma, Xiaodan; Liu, Yanyan

    2016-01-01

    The onion maggot, Delia antiqua, is a devastating pest of liliaceous crops and current control measures fail to avert pesticide residues, threats to agroecosystem, and costly expenditures. Insect growth regulators (IGRs) are used as trypetid pest chemosterilants for their suppression on adult fertility and fecundity, but their effects on onion flies are unknown. Here, three IGRs (lufenuron, cyromazine, pyriproxyfen) were incorporated into baits to evaluate their effects on onion fly survival, fecundity, fertility, susceptibility of adults in different ages and offspring development. Lufenuron and cyromazine did not affect survival of new-emerged adults, but lufenuron inhibited adult fertility without affecting fecundity, and cyromazine reduced fertility and fecundity. Differently, pyriproxyfen enhanced fecundity within 10 days after treatment, while it reduced adult survival without affecting fertility. The fertility of younger adults was affected by lufenuron and cyromazine whereas the fecundity was affected with cyromazine and pyriproxyfen. For offspring of onion flies treated with lufenuron or cyromazine, most of larvae died within 5 days after hatch, but surviving larvae pupated and emerged normally. Pyriproxyfen did not affect offspring larval survival or pupation but affected pupal emergence. Thus, lufenuron and cyromazine could be potential chemosterilants for onion flies. PMID:27619006

  7. Insight into the possible mechanism of the summer diapause of Delia antiqua (Diptera: Anthomyiidae) through digital gene expression analysis.

    Science.gov (United States)

    Hao, You-Jin; Zhang, Yu-Juan; Si, Feng-Ling; Fu, Dan-Ying; He, Zheng-Bo; Chen, Bin

    2016-06-01

    The onion fly, Delia antiqua, is a major underground agricultural pest that can enter pupal diapause in the summer and winter seasons. However, little is known about its molecular regulation due to the lack of genomic resources. To gain insight into the possible mechanism of summer diapause (SD), high-throughput RNA-Seq data were generated from non-diapause (ND) and SD (initial, maintenance and quiescence phase) pupae. Three pair-wise comparisons were performed and identified, 1380, 1471 and 435, and were significantly regulated transcripts. Further analysis revealed that the enrichment of several functional terms related to juvenile hormone regulation, cell cycle, carbon hydrate and lipid metabolism, innate immune and stress responses, various signalling transductions, ubiquitin-dependent proteosome, and variation in cuticular and cytoskeleton components were found between ND and SD and between different phases of SD. Global characterization of transcriptome profiling between SD and ND contributes to the in-depth elucidation of the molecular mechanism of SD. Our results also offer insights into the evolution of insect diapause and support the importance of using the onion fly as a model to compare the molecular regulation events of summer and winter diapauses.

  8. cDNA Cloning and Sequence Analysis of ADH Gene in Delia antiqua%葱蝇ADH基因的克隆及序列分析

    Institute of Scientific and Technical Information of China (English)

    陈春露; 陈斌; 司风玲; 何正波

    2012-01-01

    【目的】对葱蝇(De如antiqua)ADH基因进行克隆,并对其进行序列分析。【方法】通过RACE的方法克隆葱蝇ADH基因的cDNA序列,同时对该序列进行同源性分析、氨基酸序列比对和系统发育分析。[结果]试验获得的cDNA全长1088bp,其中ORF771bp,编码256个氨基酸,推测其相对分子质量为30.80kDa,等电点为8.22;通过该基因推导的氨基酸序列与其他物种的ADH进行相似性比较和系统发育分析,发现葱蝇与刺舌蝇(Glossina morsitans morsitoas)氨基酸序列的同源性最高。【结论】该研究为ADH基因的进一步研究提供了基础。%[Objective] This study aims to conduct cloning and sequence analysis of ADH gene in D. Antiqua. [Method] Full-length cDNA of ADH gene in D. antiqua was cloned by using RACE technology (GenBank access number: JQ666006). Analysis of the homology, characteristics and functional domains of ADH sequence and the phy- Iogenetic relationship to other dipteran ADH were conducted. [Result] The full length of ADH cDNA is 1 088 bp containing a 771 bp of ORF, encoding 256 amino acids, with a calculated relative molecular weight of 30.80 kDa and a theoretical isoelectric point of 8.22. The deduced amino acid sequence shares the highest homology with Glossina morsitans morsitans based on homological analysis and phylogenetic analysis. [Conclusion] This study provides basis for further research of ADH gene.

  9. cDNA Cloning and Sequence Analysis of ADH Gene in Delia antiqua%葱蝇ADH基因的克隆及序列分析

    Institute of Scientific and Technical Information of China (English)

    陈春露; 陈斌; 司风玲; 何正波

    2012-01-01

    [ Objective ] The aim was to clone the ADH gene of Delia antiqun, and carry out a sequence analysis. [ Method ] The cDNA sequence of ADH gene was cloned with the method of RACE, and then studied with homology analysis, comparison of amino acid sequence and phylogenetic analysis. [Result] The full length of cDNA obtained was 1 088 bp, among which there were 771 bp of ORF, encoding a protein of 256 amino acids with a calculated molecular weight of 30.80 kKa and a theoretical isolectric point of 8.22. The deduced amino acid sequence had the highest identity with that of Glossina morsitans based on homological analysis,and a phylogenic tree was inferred with homological ADH sequences from other insects. [ Conclusion ] The study provides a basis for the further research of ADH gene.%[目的]对葱蝇(Delia antiqua)ADH基因进行克隆,并对其进行序列分析.[方法]通过RACE的方法克隆葱蝇ADH基因的cDNA序列,同时对该序列进行同源性分析、氨基酸序列比对和系统发育分析.[结果]试验获得的cDNA全长1 088 bp,其中ORF 771 bp,编码256个氨基酸,推测其相对分子质量为30.80 kDa,等电点为8.22;通过该基因推导的氨基酸序列与其他物种的ADH进行相似性比较和系统发育分析,发现葱蝇与刺舌蝇(Glossina morsuans)氨基酸序列的同源性最高.[结论]该研究为ADH基因的进一步研究提供了基础.

  10. Evident?

    DEFF Research Database (Denmark)

    Plant, Peter

    2012-01-01

    Quality assurance and evidence in career guidance in Europe are often seen as self-evident approaches, but particular interests lie behind......Quality assurance and evidence in career guidance in Europe are often seen as self-evident approaches, but particular interests lie behind...

  11. Balancing innovation and evidence.

    Science.gov (United States)

    Pilcher, Jobeth W

    2015-01-01

    Nurse educators are encouraged to use evidence to guide their teaching strategies. However, evidence is not always available. How can educators make decisions regarding strategies when data are limited or absent? Where do innovation and creativity fit? How can innovation be balanced with evidence? This article provides a discussion regarding other sources of evidence, such as extrapolations, theories and principles, and collective expertise. Readers are encouraged to review the options and then analyze how they might be applied to innovation in education.

  12. The Evidence Movement

    DEFF Research Database (Denmark)

    Hansen, Hanne Foss; Rieper, Olaf

    2009-01-01

    The evidence movement and the idea of systematic reviews, defined as summaries of the results of already existing evaluation and research projects, have gained considerable support in recent years as many international as well as national evidence-producing organizations have been established....... This article analyses how the idea is practised in the areas of health, social welfare and education and shows that evidence-producing organizations work differently. Some subscribe to the hierarchy of evidence, others to a typology of evidence. The consequences of these variations are discussed....

  13. Evidence informed decision making

    DEFF Research Database (Denmark)

    Sharma, Tarang; Choudhury, Moni; Kaur, Bindweep;

    2015-01-01

    OBJECTIVES: Colloquial evidence (CE) has been described as the informal evidence that helps provide context to other forms of evidence in guidance development. Despite challenges around quality, and the potential biases, the use of CE is becoming increasingly important in assessments where...... from the literature and a combined best practice checklist has been proposed. CONCLUSIONS: As decisions often need to be made in areas where there is a lack of published scientific evidence, CE is employed. Therefore to ensure its appropriateness the development of a validated CE data quality check......-list to assist decision makers is essential and further research in this area is a priority....

  14. Balancing innovation and evidence.

    Science.gov (United States)

    Pilcher, Jobeth W

    2015-01-01

    Nurse educators are encouraged to use evidence to guide their teaching strategies. However, evidence is not always available. How can educators make decisions regarding strategies when data are limited or absent? Where do innovation and creativity fit? How can innovation be balanced with evidence? This article provides a discussion regarding other sources of evidence, such as extrapolations, theories and principles, and collective expertise. Readers are encouraged to review the options and then analyze how they might be applied to innovation in education. PMID:25790361

  15. Evidence based practice

    DEFF Research Database (Denmark)

    Hjørland, Birger

    2011-01-01

    Evidence-based practice (EBP) is an influential interdisciplinary movement that originated in medicine as evidence-based medicine (EBM) about 1992. EBP is of considerable interest to library and information science (LIS) because it focuses on a thorough documentation of the basis for the decision...... is that practitioners lose their autonomy, that the understanding of theory and of underlying mechanisms is weakened, and that the concept of evidence is too narrow in the empiricist tradition. In this article, it is suggested that we should speak of “research-based practice” rather than EBP, because this term is open...... to more fruitful epistemologies and provides a broader understanding of evidence.The focus on scientific argumentation in EBP is an important contribution from EBP to LIS, which is long overdue, but parts of the underlying epistemological assumptions should be replaced: EBP is too narrow, too formalist...

  16. Gait as evidence

    DEFF Research Database (Denmark)

    Lynnerup, Niels; Larsen, Peter Kastmand

    2014-01-01

    This study examines what in Denmark may constitute evidence based on forensic anthropological gait analyses, in the sense of pointing to a match (or not) between a perpetrator and a suspect, based on video and photographic imagery. Gait and anthropometric measures can be used when direct facial...... comparison is not possible because of perpetrators masking their faces. The nature of judicial and natural scientific forms of evidence is discussed, and rulings dealing with the admissibility of video footage and forensic evidence in general are given. Technical issues of video materials are discussed......, and the study also discusses how such evidence may be presented, both in written statements and in court. © The Institution of Engineering and Technology 2014....

  17. Evidence-Based Development

    DEFF Research Database (Denmark)

    Hertzum, Morten; Simonsen, Jesper

    2004-01-01

    Systems development is replete with projects that represent substantial resource investments but result in systems that fail to meet users’ needs. Evidence-based development is an emerging idea intended to provide means for managing customer-vendor relationships and working systematically toward...... and electronic patient records for diabetes patients, this paper reports research in progress regarding the prospects and pitfalls of evidence-based development....

  18. Evidence based pediatrics.

    OpenAIRE

    Elizabeta ZISOVSKA

    2015-01-01

    It is very difficult to define the entire phrase “Evidence based pediatrics”, covering all components of this overused sentence. The definition comes out of the common sentence and it means integration of the individual clinical expertize together with the best external clinically available evidence of the systematic reviews which are of interest and benefit of the individual patient.Development of clinically appropriate structured question follows PICO model, i.e. containing f...

  19. What is Evidence? (editorial

    Directory of Open Access Journals (Sweden)

    Denise Koufogiannakis

    2011-06-01

    Full Text Available Lately, I have been pondering what we really mean when we say “evidence based practice”? In LIS, we all know the definitions that have been proposed (Booth 2000, Eldredge 2000, Crumley and Koufogiannakis 2002, and which have not ever really been challenged. But have we ever said explicitly what qualifies as evidence in this model? The underlying assumption seems to be that evidence is research, hence, we are really talking about research-based practice, but we don’t actually use that term.Higgs and Jones (2000 note that evidence is “knowledge derived from a variety of sources that has been subjected to testing and has found to be credible.” The Oxford English Dictionary states that evidence is “something serving as a proof” (OED, 2011. Neither of these definitions of evidence notes that evidence equals research; research is only one form of evidence. It certainly isn’t the only form of evidence – so what, then, constitutes evidence?Rycroff-Malone et al. (2004 state that that in order for evidence based practice to create a broader evidence base in nursing, “the external, scientific and the internal, intuitive” need to be brought together. The external, scientific is what evidence based practice has been focused on, in the form of scientific research, but Rycroff-Malone et al. note that other elements such as clinical experience, patient experience, and information from the local context also need to be considered.In library and information practice, what are the other forms of evidence we need to consider? I propose that while research evidence is of high importance to our profession and knowledge, LIS practitioners need to first of all consider local evidence. Local evidence is found in our working environment and specific to the context in which we carry out our work. It includes such things as our experiences with patrons in particular contexts, and what we observe to work in such situations, assessment of programs

  20. Evidence-based dentistry.

    Science.gov (United States)

    Chambers, David W

    2010-01-01

    Both panegyric and criticism of evidence-based dentistry tend to be clumsy because the concept is poorly defined. This analysis identifies several contributions to the profession that have been made under the EBD banner. Although the concept of clinicians integrating clinical epidemiology, the wisdom of their practices, and patients' values is powerful, its implementation has been distorted by a too heavy emphasis of computerized searches for research findings that meet the standards of academics. Although EBD advocates enjoy sharing anecdotal accounts of mistakes others have made, faulting others is not proof that one's own position is correct. There is no systematic, high-quality evidence that EBD is effective. The metaphor of a three-legged stool (evidence, experience, values, and integration) is used as an organizing principle. "Best evidence" has become a preoccupation among EBD enthusiasts. That overlong but thinly developed leg of the stool is critiqued from the perspectives of the criteria for evidence, the difference between internal and external validity, the relationship between evidence and decision making, the ambiguous meaning of "best," and the role of reasonable doubt. The strongest leg of the stool is clinical experience. Although bias exists in all observations (including searches for evidence), there are simple procedures that can be employed in practice to increase useful and objective evidence there, and there are dangers in delegating policy regarding allowable treatments to external groups. Patient and practitioner values are the shortest leg of the stool. As they are so little recognized, their integration in EBD is problematic and ethical tensions exist where paternalism privileges science over patient's self-determined best interests. Four potential approaches to integration are suggested, recognizing that there is virtually no literature on how the "seat" of the three-legged stool works or should work. It is likely that most dentists

  1. Lineamenti del rinnovato processo contenzioso amministrativo ecclesiale. Commento al m.p. Antiqua ordinatione di Benedetto XVI (parte seconda)

    OpenAIRE

    Manuel Ganarin

    2011-01-01

    Contributo segnalato dalla prof.ssa Geraldina Boni, ordinario di Storia del Diritto canonico e dal prof. Andrea Zanotti, ordinario di Diritto canonico nella Facoltà di Giurisprudenza dell’Università degli Studi di Bologna, che ne attestano la scientificità e l’originalità.La prima parte del contributo, sino al punto n. 3 della Parte Seconda, è stato pubblicato nel mese di luglio del 2011. SOMMARIO: PARTE PRIMA: CONSIDERAZIONI PRELIMINARI – 1. “Signatura Apostolica lege propria regitur” (cost....

  2. Lineamenti del rinnovato processo contenzioso amministrativo ecclesiale. Commento al m.p. Antiqua ordinatione di Benedetto XVI

    OpenAIRE

    Manuel Ganarin

    2011-01-01

    Contributo segnalato dalla prof.ssa Geraldina Boni, ordinario di Storia del Dirittocanonico e dal prof. Andrea Zanotti, ordinario di Diritto canonico nella Facoltà diGiurisprudenza dell’Università degli Studi di Bologna, che ne attestano la scientificitàe l’originalità.In questa uscita se ne pubblica il testo sino al punto n. 3 della Parte Seconda.SOMMARIO: PARTE PRIMA: CONSIDERAZIONI PRELIMINARI – 1. “SignaturaApostolica lege propria regitu...

  3. Lineamenti del rinnovato processo contenzioso amministrativo ecclesiale. Commento al m.p. Antiqua ordinatione di Benedetto XVI

    Directory of Open Access Journals (Sweden)

    Manuel Ganarin

    2011-07-01

    Full Text Available Contributo segnalato dalla prof.ssa Geraldina Boni, ordinario di Storia del Dirittocanonico e dal prof. Andrea Zanotti, ordinario di Diritto canonico nella Facoltà diGiurisprudenza dell’Università degli Studi di Bologna, che ne attestano la scientificitàe l’originalità.In questa uscita se ne pubblica il testo sino al punto n. 3 della Parte Seconda.SOMMARIO: PARTE PRIMA: CONSIDERAZIONI PRELIMINARI – 1. “SignaturaApostolica lege propria regitur” (cost. ap. Pastor Bonus, art. 125. Il definitivosuperamento delle Normae speciales e l’adeguata sistemazione della novellalegislazione benedettina nell’articolato sistema delle fonti del diritto – 2. I trattidistintivi della Lex propria: in particolare, la sua ispirazione pragmatica el’evoluzione della “nomenclatura” canonistica in materia di giustiziaamministrativa – 3. La Segnatura Apostolica quale tribunal administrativum. Spuntiper un’interpretazione sistematica del controverso c. 1400, § 2 CIC, conformementeall’indole definitoria della normativa codiciale ecclesiale – PARTE SECONDA:DISAMINA DELLA RATIO PROCEDENDI INTERNA AL SUPREMO FOROGIUDIZIARIO – 1. Prima fase – a L’interposizione del ricorso entro i limiti didecadenza posti all’esercizio del diritto fondamentale al giudizio e l’eventualeconcessione della remissio in terminos a favore del ricorrente – b Contenuto,allegati e capita nullitatis dell’istanza introduttiva del giudizio – 2. La reiectio inlimine dell’istanza irricevibile. Il controllo essenzialmente formale del Segretariodel Supremo Tribunale della Segnatura – a La non pertinenza dell’oggettosostanziale della domanda – b Presupposti e condizioni del ricorso di legittimità.In particolare, la capacitas standi in iudicio e la legitimatio activa della partericorrente – c L’inesistenza dell’oggetto formale del ricorso – d La decorrenza deltermine per ricorrere: il c.d. ricorso tardivo – 3. Seconda fase: le attività delSegretario conseguenti all’accettazione preliminare del ricorso – a Premessa:l’identificazione dei soggetti del giudizio e la vexata quaestio relativa al possibileconflitto interistituzionale fra l’autorità amministrativa ecclesiastica inferiore ed ilcompetente Dicastero della Curia Romana – b Ricorrente, resistente,controinteressato e terzi interventori. Parti principali e parti accessorie del processoamministrativo – c Contenzioso amministrativo e collaborazione fra istituzioniecclesiali. L’esibizione del provvedimento impugnato e degli acta causae da partedel Dicastero resistente – d Il votum pro rei veritate e la peculiare “bidirezionalità”delle funzioni conferite al Promotore di giustizia – 4. L’attuazione delcontraddittorio processuale nell’espletamento della c.d. istruttoria “documentale” –5. Il giudizio di ammissibilità del Prefetto in Congresso – a La divaricazione traimpostazioni dottrinali e prassi applicativa relativamente al concetto di “manifestainfondatezza” del ricorso – b Segue. La riformulazione, de iure condendo, delladiagnosi prefettizia e della struttura “trifasica” del processo contenzioso amministrativo canonico – 6. Terza fase: dalla contestazione della lite alla decisionedel Collegium iudicans – a La summaria delibatio oralis, il c.d. supplementod’istruttoria ed il compimento della fase decisoria – b Gli effetti tipici del giudicatoamministrativo di rigetto. L’effetto “caducatorio” della sentenza di accoglimento ela sua incidenza nel sistema delle invalidità dell’atto giuridico canonico – c Segue.L’effetto “ripristinatorio” e l’effetto “conformativo” conseguenti all’annullamentodella decisione impugnata – 7. La crisi irreversibile del processo amministrativo. Leipotesi di litis finitio previste dal Codex iuris canonici e dalla Lex propria – a Lamorte del ricorrente e la c.d. ”sopravvenuta carenza di interesse” – b La persistenteinerzia delle parti: la perenzione – c La rinuncia all’istanza giudiziale – d Larevoca del provvedimento amministrativo – e La composizione pacifica dellacontroversia – 8. La sospensione giudiziale dell’esecuzione dell’atto amministrativosingolare – a Vincolatività ed automaticità della tutela cautelare: il ricorso tantumin devolutivo ed il ricorso etiam in suspensivo – b I presupposti giuridici esostanziali per la concessione della misura sospensiva – c Il procedimentoincidentale: dal giudizio preliminare del Segretario alla deliberazione delCardinale Prefetto

  4. Lineamenti del rinnovato processo contenzioso amministrativo ecclesiale. Commento al m.p. Antiqua ordinatione di Benedetto XVI (parte seconda

    Directory of Open Access Journals (Sweden)

    Manuel Ganarin

    2011-09-01

    Full Text Available Contributo segnalato dalla prof.ssa Geraldina Boni, ordinario di Storia del Diritto canonico e dal prof. Andrea Zanotti, ordinario di Diritto canonico nella Facoltà di Giurisprudenza dell’Università degli Studi di Bologna, che ne attestano la scientificità e l’originalità.La prima parte del contributo, sino al punto n. 3 della Parte Seconda, è stato pubblicato nel mese di luglio del 2011. SOMMARIO: PARTE PRIMA: CONSIDERAZIONI PRELIMINARI – 1. “Signatura Apostolica lege propria regitur” (cost. ap. Pastor Bonus, art. 125. Il definitivo superamento delle Normae speciales e l’adeguata sistemazione della novella legislazione benedettina nell’articolato sistema delle fonti del diritto – 2. I tratti distintivi della Lex propria: in particolare, la sua ispirazione pragmatica e l’evoluzione della “nomenclatura” canonistica in materia di giustizia amministrativa – 3. La Segnatura Apostolica quale tribunal administrativum. Spunti per un’interpretazione sistematica del controverso c. 1400, § 2 CIC, conformemente all’indole definitoria della normativa codiciale ecclesiale – PARTE SECONDA: DISAMINA DELLA RATIO PROCEDENDI INTERNA AL SUPREMO FORO GIUDIZIARIO – 1. Prima fase – a L’interposizione del ricorso entro i limiti di decadenza posti all’esercizio del diritto fondamentale al giudizio e l’eventuale concessione della remissio in terminos a favore del ricorrente – b Contenuto, allegati e capita nullitatis dell’istanza introduttiva del giudizio – 2. La reiectio in limine dell’istanza irricevibile. Il controllo essenzialmente formale del Segretario del Supremo Tribunale della Segnatura – a La non pertinenza dell’oggetto sostanziale della domanda – b Presupposti e condizioni del ricorso di legittimità. In particolare, la capacitas standi in iudicio e la legitimatio activa della parte ricorrente – c L’inesistenza dell’oggetto formale del ricorso – d La decorrenza del termine per ricorrere: il c.d. ricorso tardivo – 3. Seconda fase: le attività del Segretario conseguenti all’accettazione preliminare del ricorso – a Premessa: l’identificazione dei soggetti del giudizio e la vexata quaestio relativa al possibile conflitto interistituzionale fra l’autorità amministrativa ecclesiastica inferiore ed il competente Dicastero della Curia Romana – b Ricorrente, resistente, controinteressato e terzi interventori. Parti principali e parti accessorie del processo amministrativo – c Contenzioso amministrativo e collaborazione fra istituzioni ecclesiali. L’esibizione del provvedimento impugnato e degli acta causae da parte del Dicastero resistente – d Il votum pro rei veritate e la peculiare “bidirezionalità” delle funzioni conferite al Promotore di giustizia – 4. L’attuazione del contraddittorio processuale nell’espletamento della c.d. istruttoria “documentale” – 5. Il giudizio di ammissibilità del Prefetto in Congresso – a La divaricazione tra impostazioni dottrinali e prassi applicativa relativamente al concetto di “manifesta infondatezza” del ricorso – b Segue. La riformulazione, de iure condendo, della diagnosi prefettizia e della struttura “trifasica” del processo contenzioso amministrativo canonico – 6. Terza fase: dalla contestazione della lite alla decisione del Collegium iudicans – a La summaria delibatio oralis, il c.d. supplemento d’istruttoria ed il compimento della fase decisoria – b Gli effetti tipici del giudicato amministrativo di rigetto. L’effetto “caducatorio” della sentenza di accoglimento e la sua incidenza nel sistema delle invalidità dell’atto giuridico canonico – c Segue. L’effetto “ripristinatorio” e l’effetto “conformativo” conseguenti all’annullamento della decisione impugnata – 7. La crisi irreversibile del processo amministrativo. Le ipotesi di litis finitio previste dal Codex iuris canonici e dalla Lex propria – a La morte del ricorrente e la c.d. ”sopravvenuta carenza di interesse” – b La persistente inerzia delle parti: la perenzione – c La rinuncia all’istanza giudiziale – d La revoca del provvedimento amministrativo – e La composizione pacifica della controversia – 8. La sospensione giudiziale dell’esecuzione dell’atto amministrativo singolare – a Vincolatività ed automaticità della tutela cautelare: il ricorso tantum in devolutivo ed il ricorso etiam in suspensivo – b I presupposti giuridici e sostanziali per la concessione della misura sospensiva – c Il procedimento incidentale: dal giudizio preliminare del Segretario alla deliberazione del Cardinale Prefetto

  5. The Appraising Evidence Game.

    Science.gov (United States)

    Mick, JoAnn

    2016-04-01

    This column shares the best evidence-based strategies and innovative ideas on how to facilitate the learning of EBP principles and processes by clinicians as well as nursing and interprofessional students. Guidelines for submission are available at http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1741-6787. PMID:26766171

  6. Evidence of Absence software

    Science.gov (United States)

    Dalthorp, Daniel; Huso, Manuela M. P.; Dail, David; Kenyon, Jessica

    2014-01-01

    Evidence of Absence software (EoA) is a user-friendly application used for estimating bird and bat fatalities at wind farms and designing search protocols. The software is particularly useful in addressing whether the number of fatalities has exceeded a given threshold and what search parameters are needed to give assurance that thresholds were not exceeded. The software is applicable even when zero carcasses have been found in searches. Depending on the effectiveness of the searches, such an absence of evidence of mortality may or may not be strong evidence that few fatalities occurred. Under a search protocol in which carcasses are detected with nearly 100 percent certainty, finding zero carcasses would be convincing evidence that overall mortality rate was near zero. By contrast, with a less effective search protocol with low probability of detecting a carcass, finding zero carcasses does not rule out the possibility that large numbers of animals were killed but not detected in the searches. EoA uses information about the search process and scavenging rates to estimate detection probabilities to determine a maximum credible number of fatalities, even when zero or few carcasses are observed.

  7. A generalized evidence distance

    Institute of Scientific and Technical Information of China (English)

    Hongming Mo; Xi Lu; Yong Deng

    2016-01-01

    How to efficiently measure the distance between two basic probability assignments (BPAs) is an open issue. In this paper, a new method to measure the distance between two BPAs is proposed, based on two existing measures of evidence distance. The new proposed method is comprehen-sive and generalized. Numerical examples are used to ilus-trate the effectiveness of the proposed method.

  8. What Counts as Evidence?

    Science.gov (United States)

    Dougherty Stahl, Katherine A.

    2014-01-01

    Each disciplinary community has its own criteria for determining what counts as evidence of knowledge in their academic field. The criteria influence the ways that a community's knowledge is created, communicated, and evaluated. Situating reading, writing, and language instruction within the content areas enables teachers to explicitly…

  9. Inflation, evidence and falsifiability

    CERN Document Server

    Gubitosi, Giulia; Magueijo, Joao; Allison, Rupert

    2015-01-01

    In this paper we consider the issue of paradigm evaluation by applying Bayes' theorem along the following nested chain of progressively more complex structures: i) parameter estimation (within a model), ii) model selection and comparison (within a paradigm), iii) paradigm evaluation. In such a chain the Bayesian evidence works both as the posterior's normalization at a given level and as the likelihood function at the next level up. Whilst raising no objections to the standard application of the procedure at the two lowest levels, we argue that it should receive an essential modification when evaluating paradigms, in view of the issue of falsifiability. By considering toy models we illustrate how unfalsifiable models and paradigms are always favoured by the Bayes factor. We argue that the evidence for a paradigm should not only be high for a given dataset, but exceptional with respect to what it would have been, had the data been different. We propose a measure of falsifiability (which we term predictivity), ...

  10. NCCN Evidence Blocks.

    Science.gov (United States)

    Carlson, Robert W; Jonasch, Eric

    2016-05-01

    NCCN has developed a series of Evidence Blocks: graphics that provide ratings for each recommended treatment regimen in terms of efficacy, toxicity, quality and consistency of the supporting data, and affordability. The NCCN Evidence Blocks are currently available in 10 tumor types within the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines). At a glance, patients and providers can understand how a given treatment was assessed by the NCCN Guidelines Panel and get a sense of how a given treatment may match individual needs and preferences. Robert W. Carlson, MD, CEO of NCCN, described the reasoning behind this new feature and how the tool is used, and Eric Jonasch, MD, Professor of Genitourinary Medical Oncology at The University of Texas MD Anderson Cancer Center, and Vice Chair of the NCCN Kidney Cancer Panel, described its applicability in the management of metastatic renal cell carcinoma. PMID:27226499

  11. The Evidence on Globalization

    OpenAIRE

    Potrafke, Niklas

    2014-01-01

    Globalization is blamed for many socio-economic shortcomings. I discuss the consequences of globalization by surveying the empirical globalization literature. My focus is on the KOF indices of globalization (Dreher 2006a and Dreher et al. 2008a), that have been used in more than 100 studies. Early studies using the KOF index reported correlations between globalization and several outcome variables. Studies published more recently identify causal effects. The evidence shows that globalization ...

  12. Evidence Standards and Litigation

    DEFF Research Database (Denmark)

    Guerra, Alice; Luppi, Barbara; Parisi, Francesco

    In litigation models, the parties’ probability to succeed in a lawsuit hinge upon two main factors: the merits of the parties’ claims and their litigation efforts (Katz, 1988; Hirshleifer, 1989; Farmer and Pecorino, 1999). In this paper we extend this framework to consider an important procedural...... for low-merit cases when standards are set high. This provides a valuable key for understanding the sorting effect of evidence standards and their role as a policy instrument in civil litigation....

  13. Insufficient Evidence: The Problems of Evidence-Based Nursing.

    Science.gov (United States)

    Rolfe, Gary

    1999-01-01

    Challenges the wisdom of basing nursing practice on the findings of statistical research and offers objections to the philosophy of evidence-based nursing. Proposes rethinking what counts as evidence, suggesting a model based on reflection after the event. (SK)

  14. Evidence in mental health.

    Science.gov (United States)

    Weeks, Susan Mace

    2014-12-01

    Health practitioners wishing to positively improve health outcomes for their clients have access to a unique set of collated tools to guide their practice. Systematic reviews provide guidance in the form of synthesized evidence that can form the basis of decision making as they provide care for their clients. This article describes systematic reviews as a basis for informed decision making by mental health practitioners. The process of systematic review is discussed, examples of existing systematic review topics relevant to mental health are presented, a sample systematic review is described, and gaps and emerging topics for mental health systematic reviews are addressed.

  15. Evidence and Ethics (Editorial)

    OpenAIRE

    Alison Brettle

    2012-01-01

    Welcome to the December issue of EBLIP, the final issue of my first year as Editor-in-Chief. A year which I have thoroughly enjoyed and one where the fears over what to write in my editorials haven’t materialised. This quarter, ethics has featured quite heavily in my working life so I decided to make this the topic of the editorial, sharing some of my thoughts regarding evidence, ethics and how ethical principles are implemented within the EBLIP journal.Ethics are “principles of conduct or st...

  16. Evidence on Inclusion

    DEFF Research Database (Denmark)

    Dyssegaard, Camilla Brørup; Larsen, Michael Søgaard

    The purpose of this publication is to examine existing research on inclusion to identify strategies of inclusion that have generated positive effects. To do so it is necessary to understand the effect of the applied strategies. One approach, which is being discussed, is to use evidence to determine...... which methods have proven more effective than others. The desire to gain insight into research on inclusion forms the basis of the current systematic review. The task was to determine which strategies primary research has found to be most effective for inclusion purposes. We have solved this task...

  17. Realism And Empirical Evidence

    CERN Document Server

    Schmelzer, I

    1997-01-01

    We define realism using a slightly modified version of the EPR criterion of reality. This version is strong enough to show that relativity is incomplete. We show that this definition of realism is nonetheless compatible with the general principles of causality and canonical quantum theory as well as with experimental evidence in the (special and general) relativistic domain. We show that the realistic theories we present here, compared with the standard relativistic theories, have higher empirical content in the strong sense defined by Popper's methodology.

  18. Evidence for homosexuality gene

    Energy Technology Data Exchange (ETDEWEB)

    Pool, R.

    1993-07-16

    A genetic analysis of 40 pairs of homosexual brothers has uncovered a region on the X chromosome that appears to contain a gene or genes for homosexuality. When analyzing the pedigrees of homosexual males, the researcheres found evidence that the trait has a higher likelihood of being passed through maternal genes. This led them to search the X chromosome for genes predisposing to homosexuality. The researchers examined the X chromosomes of pairs of homosexual brothers for regions of DNA that most or all had in common. Of the 40 sets of brothers, 33 shared a set of five markers in the q28 region of the long arm of the X chromosome. The linkage has a LOD score of 4.0, which translates into a 99.5% certainty that there is a gene or genes in this area that predispose males to homosexuality. The chief researcher warns, however, that this one site cannot explain all instances of homosexuality, since there were some cases where the trait seemed to be passed paternally. And even among those brothers where there was no evidence that the trait was passed paternally, seven sets of brothers did not share the Xq28 markers. It seems likely that homosexuality arises from a variety of causes.

  19. Evidence-Based Laboratory Medicine

    Institute of Scientific and Technical Information of China (English)

    Christopher P Price

    2004-01-01

    @@ Whilst there have been several definitions of Evidence-Based Medicine (EBM), the one given by David Sackett is probably the most accurate and well accepted; he stated that "evidence-based medicine is the conscientious, explicit and judicious use of current best evidence in making decisions about the care of individual patients"[1].

  20. Evidence of me” in evidence based medicine?

    OpenAIRE

    Lockwood, Susan

    2004-01-01

    Evidence based medicine provides independent, validated advice about treatment options, but does it take sufficient account of individual patients' values to provide them with an optimal health outcome?

  1. Synthesizing Quantitative Evidence for Evidence-based Nursing: Systematic Review.

    Science.gov (United States)

    Oh, Eui Geum

    2016-06-01

    As evidence-based practice has become an important issue in healthcare settings, the educational needs for knowledge and skills for the generation and utilization of healthcare evidence are increasing. Systematic review (SR), a way of evidence generation, is a synthesis of primary scientific evidence, which summarizes the best evidence on a specific clinical question using a transparent, a priori protocol driven approach. SR methodology requires a critical appraisal of primary studies, data extraction in a reliable and repeatable way, and examination for validity of the results. SRs are considered hierarchically as the highest form of evidence as they are a systematic search, identification, and summarization of the available evidence to answer a focused clinical question with particular attention to the methodological quality of studies or the credibility of opinion and text. The purpose of this paper is to introduce an overview of the fundamental knowledge, principals and processes in SR. The focus of this paper is on SR especially for the synthesis of quantitative data from primary research studies that examines the effectiveness of healthcare interventions. To activate evidence-based nursing care in various healthcare settings, the best and available scientific evidence are essential components. This paper will include some examples to promote understandings. PMID:27349664

  2. Limits of Evidence within EU

    Directory of Open Access Journals (Sweden)

    Monica Pocora

    2015-05-01

    Full Text Available The issue of admissibility of evidence has been regulated only very scarcely in the EU. Judicial cooperation in criminal matters has been embracing the increasing number of instruments, covering plethora of aspects, however, the field of admissibility of evidence remains almost untouched. Can the Area of Freedom, Security and Justice be called the Common Evidence Area? From the national perspective, the issue of admissibility of evidence is still subject to divergent solutions in the Member States, concerning the common law and continental law systems, i.e. the right of access to a lawyer. Thus, the paper aims to take into account the tendencies of legal rule in matter of admissibility of evidence, the dynamic of evidence movement within EU area.

  3. When Lack of Evidence Is Evidence of Lack.

    Science.gov (United States)

    Pickering, Neil

    2015-12-01

    In their recent article "A Gentle Ethical Defence of Homeopathy," Levy, Gadd, Kerridge, and Komesaroff use the claim that "lack of evidence is not equivalent to evidence of lack" as a component of their ethical defence of homeopathy. In response, this article argues that they cannot use this claim to shore up their ethical arguments. This is because it is false. PMID:26631232

  4. Evidence and Ethics (Editorial

    Directory of Open Access Journals (Sweden)

    Alison Brettle

    2012-12-01

    Full Text Available Welcome to the December issue of EBLIP, the final issue of my first year as Editor-in-Chief. A year which I have thoroughly enjoyed and one where the fears over what to write in my editorials haven’t materialised. This quarter, ethics has featured quite heavily in my working life so I decided to make this the topic of the editorial, sharing some of my thoughts regarding evidence, ethics and how ethical principles are implemented within the EBLIP journal.Ethics are “principles of conduct or standards of behaviour governing an individual or profession” (Library and Information Science Editorial Committee, 2010, and as individuals or professionals we may be governed by various ethical codes. As I'm sure you know, EBLIP originated in the health domain, where ethical values and ethical research feature strongly. Indeed, by its formal definition, research cannot take place unless “ethical approval” from an appropriate committee has been granted. The practicalities of taking research through the ethical approval process can often be time consuming, and those involved in research need to bear this in mind when planning a project. Each committee will have a slightly different form and process (which can add to the frustration of the researcher, but basically will make their decision to approve on the basis that the research includes obtaining informed consent from participants (i.e., participants know what the research is about and what their involvement will mean; that the research will not cause harm to participants; that confidentiality will be maintained; and that the research undertaken is methodologically rigorous and worthwhile. Preparing a proposal for ethical approval, whilst time consuming, makes the researcher think about all aspects of the research and how it is going to be operationalized, which can save lots of time and effort in the long run and may well also improve the research design. These principles are the same whatever

  5. Psiquiatria baseada em evidências Evidence-based psychiatry

    Directory of Open Access Journals (Sweden)

    Maurício S de Lima

    2000-09-01

    Full Text Available Em psiquiatria, observa-se grande variabilidade de práticas clínicas, muitas vezes desnecessária. Essas variações podem estar relacionadas à ausência de evidência científica confiável ou ao desconhecimento das evidências de boa qualidade disponíveis. A medicina baseada em evidências (MBE é uma combinação de estratégias que busca assegurar que o cuidado individual do paciente seja baseado na melhor informação disponível, a qual deve ser incorporada à prática clínica. Neste artigo, conceitos de MBE são discutidos com relação a aspectos e desafios no tratamento de pacientes com distimia, bulimia nervosa e esquizofrenia. A partir de resultados de três revisões sistemáticas recentemente publicadas, conclui-se que a prática de psiquiatria baseada em evidências acrescenta qualidade à prática psiquiátrica tradicional.The unnecessary variability often seen in the clinical practice can be related to both the absence of reliable evidence and unawareness of the existence of good quality evidence. Evidence-Based Medicine (EBM is a set of linked strategies designed to assist clinicians in keeping themselves up-to-date with the best available evidence. Such evidence must be incorporated into the clinical practice. EBM concepts are discussed here through common aspects and challenges doctors face when treating patients with dysthymia, bulimia nervosa, and schizophrenia. In the light of some results from three systematic reviews it is concluded that Evidence-Based Psychiatry strategies, rather than replacing the traditional ones, may be a valuable tool to improving quality in a good clinical practice.

  6. Evidence-based clinical practice

    DEFF Research Database (Denmark)

    Gluud, Christian

    2002-01-01

    Evidence-based medicine combines the patient's preferences with clinical experience and the best research evidence. Randomized clinical trials are considered the most valid research design for evaluating health-care interventions. However, empirical research shows that intervention effects may be...

  7. Standardized description of scientific evidence using the Evidence Ontology (ECO).

    Science.gov (United States)

    Chibucos, Marcus C; Mungall, Christopher J; Balakrishnan, Rama; Christie, Karen R; Huntley, Rachael P; White, Owen; Blake, Judith A; Lewis, Suzanna E; Giglio, Michelle

    2014-01-01

    The Evidence Ontology (ECO) is a structured, controlled vocabulary for capturing evidence in biological research. ECO includes diverse terms for categorizing evidence that supports annotation assertions including experimental types, computational methods, author statements and curator inferences. Using ECO, annotation assertions can be distinguished according to the evidence they are based on such as those made by curators versus those automatically computed or those made via high-throughput data review versus single test experiments. Originally created for capturing evidence associated with Gene Ontology annotations, ECO is now used in other capacities by many additional annotation resources including UniProt, Mouse Genome Informatics, Saccharomyces Genome Database, PomBase, the Protein Information Resource and others. Information on the development and use of ECO can be found at http://evidenceontology.org. The ontology is freely available under Creative Commons license (CC BY-SA 3.0), and can be downloaded in both Open Biological Ontologies and Web Ontology Language formats at http://code.google.com/p/evidenceontology. Also at this site is a tracker for user submission of term requests and questions. ECO remains under active development in response to user-requested terms and in collaborations with other ontologies and database resources. Database URL: Evidence Ontology Web site: http://evidenceontology.org.

  8. How to map the evidence

    DEFF Research Database (Denmark)

    Møller, Ann

    2012-01-01

    and sponsored many projects in order to get new products onto the market. The lack of an overview and control has led to an abundance of evidence within certain areas of our specialty, whereas other areas are scarcely, or not at all, researched. One way of 'mapping' the evidence in order to find out what we...... know and what we do not know is the production of systematic reviews. Although systematic reviews are considered top of the evidence hierarchy, they are not flawless. The aim of this article is to explain the systematic review and point to some of the challenges in the development and use of systematic...

  9. Forensic Botany: Evidence and Analysis.

    Science.gov (United States)

    Coyle, H M

    2009-01-01

    Forensic botany is the use of plant evidence in matters of law. While plant fragments are often collected as trace evidence, they are only occasionally identified using microscopy and are still more rarely assessed using molecular biology techniques for individualization and sourcing of a sample. There are many different methods useful for DNA typing of plants; this review focuses on those techniques (DNA sequencing, STR, AFLP, RAPD) most relevant to the forensic science community and on those methods currently in practice. Plant evidence is commonly associated with homicides, with clandestine graves, as trace pollen on clothing, vehicles, or packaging, or in the transport of illicit drugs. DNA can be especially useful for the identification of minute quantity of samples, for differentiation of plants that lack distinguishing morphological features, and for generating a unique identifier for associative forensic evidence.

  10. Forensic Botany: Evidence and Analysis.

    Science.gov (United States)

    Coyle, H M

    2009-01-01

    Forensic botany is the use of plant evidence in matters of law. While plant fragments are often collected as trace evidence, they are only occasionally identified using microscopy and are still more rarely assessed using molecular biology techniques for individualization and sourcing of a sample. There are many different methods useful for DNA typing of plants; this review focuses on those techniques (DNA sequencing, STR, AFLP, RAPD) most relevant to the forensic science community and on those methods currently in practice. Plant evidence is commonly associated with homicides, with clandestine graves, as trace pollen on clothing, vehicles, or packaging, or in the transport of illicit drugs. DNA can be especially useful for the identification of minute quantity of samples, for differentiation of plants that lack distinguishing morphological features, and for generating a unique identifier for associative forensic evidence. PMID:26242238

  11. NASA 2010 Pharmacology Evidence Review

    Science.gov (United States)

    Steinberg, Susan

    2011-01-01

    In 2008, the Institute of Medicine reviewed NASA's Human Research Program Evidence in assessing the Pharmacology risk identified in NASA's Human Research Program Requirements Document (PRD). Since this review there was a major reorganization of the Pharmacology discipline within the HRP, as well as a re-evaluation of the Pharmacology evidence. This panel is being asked to review the latest version of the Pharmacology Evidence Report. Specifically, this panel will: (1) Appraise the descriptions of the human health-related risk in the HRP PRD. (2) Assess the relevance and comprehensiveness of the evidence in identifying potential threats to long-term space missions. (3) Assess the associated gaps in knowledge and identify additional areas for research as necessary.

  12. Evidence-based playground design

    DEFF Research Database (Denmark)

    Refshauge, Anne Dahl; Stigsdotter, Ulrika K.; Lamm, Bettina;

    2015-01-01

    This paper develops, explores and evaluates an evidence-based approach to playground design, with a public park playground (playlab Cph) in Copenhagen as a case study. In the increasingly urbanised world, park playgrounds are valuable places that support healthy child development by providing...... opportunities for play, nature exploration and sensory stimulation. As it is increasingly expected that designers base their decisions on research evidence, there is a need to develop approaches to facilitate this, which also applies to playground design. The design of PlayLab Cph was based on relevant evidence......, best practice, and the theories of Affordances and Behaviour Settings. A post-occupancy evaluation was carried out through a questionnaire survey and observation studies, which revealed that a majority of the potential evidence-based affordances were actualised, and that the application of the theories...

  13. A New Fusion Method for Conflicting Evidence

    Institute of Scientific and Technical Information of China (English)

    彭颖; 沈怀荣; 马永一

    2011-01-01

    A new conflicting evidence fusion method is proposed for the deficiency of Dempster' s rule which can not fuse the conflicting evidence. Evidence is divided into three categories: believable evidence, non-conflicting evidence and con- flicting evidence. The influences of these three categories of evidences on fusion results when discounted are analyzed respectively. On these bases, the evidence distance and the conjunctive conflict are utilized in sequence to recognize the be- lievable evidence and non-conflicting evidence. The discounting factors of these two categories of evidences are set to one, which keeps the evidences support the true hypothesis to the greatest degree, and makes the fusion results focus onto the true hypothesis. Examples of some missile fault diagnosis show that the new method can effectively fuse the conflicting evidences, and is suited to fuse the relievable evidences. The new method improves the reliability and rationality of fusion re- sults compared with traditional methods.

  14. Evidence-based clinical practice

    DEFF Research Database (Denmark)

    Garattini, Silvio; Jakobsen, Janus C; Wetterslev, Jørn;

    2016-01-01

    Using the best quality of clinical research evidence is essential for choosing the right treatment for patients. How to identify the best research evidence is, however, difficult. In this narrative review we summarise these threats and describe how to minimise them. Pertinent literature was consi...... research are carefully considered and minimised, research results will be more valid and this will benefit patients and heath care systems....

  15. Evidence-based medicine and levels of evidence.

    Science.gov (United States)

    Wallace, David K

    2010-01-01

    Evidence-based medicine is the practice of making medical decisions based on evidence gained from applying the scientific method. Published studies are evaluated using three key questions: "Are the results valid?"; "What are the results?"; and "Can the results be applied to my patients?" The hierarchy of study methods for obtaining evidence is, in order from least to most useful: laboratory research, editorials, case reports and series, case-control studies, cohort studies, and randomized clinical trials. Retrospective case series can suffer from problems such as selection of a biased sample, mixing of treatment effects, and lack of control group. Randomized clinical trials (and meta-analyses of multiple trials) provide the highest level of evidence because randomization limits confounding and prevents bias of treatment assignment. In addition, randomized trials have standardization of interventions, prospective data collection, and masked outcome measures. Although every question cannot be addressed by a randomized clinical trial, the best available evidence should be sought and used to guide treatments. PMID:21061876

  16. Persuasive Evidence: Improving Customer Service through Evidence Based Librarianship

    Directory of Open Access Journals (Sweden)

    Wendy A. Abbott

    2006-03-01

    Full Text Available Objective - To demonstrate how evidence based practice has contributed to informaing decisions and resolving issues if concern in service delivery at Bond University Librray. Methods - This paper critically analyses three evidence based research projects conducted at Bond University Library. Each project combined a range of research methods including surveys, literature reviews and the analysis of internal performance data to find solutions to problems in library service delivery. The first research project investigated library opening hours and the feasability of twenty-four hour opening. Another project reseached questions about the management of a collection of feature films on DVD and video. The thrd project investigated issues surrounding the teaching of EndNote to undergarduate students. Results - Despite some deficiencies in the methodologies used, each evidence based research project had positive outcomes. One of the highlights asn an essential feature of the process at Bond University Library was the involvement of stakeholders. The ability to build consensus and agree action plans with stakeholders was an important outcome of that process. Conclusion - Drawing on the experience of these research projects, the paper illustrates the benefits of evidence based information practice to stimulate innovation and improve library services. Librarians, like most professionals, need to continue to develop the skills and a culture to effectively carry out evidence based practice.

  17. 42 CFR 423.1048 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Evidence. 423.1048 Section 423.1048 Public Health....1048 Evidence. Evidence may be received at the hearing even though inadmissible under the rules of evidence applicable to court procedure. The ALJ rules on the admissibility of evidence....

  18. 31 CFR 8.64 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Evidence. 8.64 Section 8.64 Money and... AND FIREARMS Disciplinary Proceedings § 8.64 Evidence. (a) Rules of evidence. The rules of evidence... shall exclude evidence which is irrelevant, immaterial, or unduly repetitious. (b)...

  19. 14 CFR 302.24 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Evidence. 302.24 Section 302.24 Aeronautics... Proceedings § 302.24 Evidence. (a) Presenting evidence. Presenting evidence at the hearing shall be limited to material evidence relevant to the issues as drawn by the pleadings or as defined in the report...

  20. 27 CFR 71.83 - Evidence.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Evidence. 71.83 Section 71... General § 71.83 Evidence. Any evidence which would be admissible under the rules of evidence governing... his case or defense by oral or documentary evidence, depositions, duly authenticated copies of...

  1. 42 CFR 498.61 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Evidence. 498.61 Section 498.61 Public Health... PROGRAM Hearings § 498.61 Evidence. Evidence may be received at the hearing even though inadmissible under the rules of evidence applicable to court procedure. The ALJ rules on the admissibility of evidence....

  2. Coarticulatory evidence in stuttered disfluencies

    Science.gov (United States)

    Arbisi-Kelm, Timothy

    2005-09-01

    While the disfluencies produced in stuttered speech surface at a significantly higher rate than those found in normal speech, it is less clear from the previous stuttering literature how exactly these disfluency patterns might differ in kind [Wingate (1988)]. One tendency found in normal speech is for disfluencies to remove acoustic evidence of coarticulation patterns [Shriberg (1999)]. This appears attributable to lexical search errors which prevent a speaker from accessing a word's phonological form; that is, coarticulation between words will fail to occur when segmental material from the following word is not retrieved. Since stuttering is a disorder which displays evidence of phonological but not lexical impairment, it was predicted that stuttered disfluencies would differ from normal errors in that the former would reveal acoustic evidence of word transitions. Eight speakers four stutterers and four control subjects participated in a narrative-production task, spontaneously describing a picture book. Preliminary results suggest that while both stutterers and controls did produce similar rates of disfluencies occurring without coarticulatory evidence, only the stutterers regularly produced disfluencies reflecting this transitional evidence. These results support the argument that disfluencies proper to stuttering result from a phonological deficit, while normal disfluencies are generally lexically based.

  3. Evidence in the learning organization

    Directory of Open Access Journals (Sweden)

    Umscheid Craig A

    2009-03-01

    Full Text Available Abstract Background Organizational leaders in business and medicine have been experiencing a similar dilemma: how to ensure that their organizational members are adopting work innovations in a timely fashion. Organizational leaders in healthcare have attempted to resolve this dilemma by offering specific solutions, such as evidence-based medicine (EBM, but organizations are still not systematically adopting evidence-based practice innovations as rapidly as expected by policy-makers (the knowing-doing gap problem. Some business leaders have adopted a systems-based perspective, called the learning organization (LO, to address a similar dilemma. Three years ago, the Society of General Internal Medicine's Evidence-based Medicine Task Force began an inquiry to integrate the EBM and LO concepts into one model to address the knowing-doing gap problem. Methods During the model development process, the authors searched several databases for relevant LO frameworks and their related concepts by using a broad search strategy. To identify the key LO frameworks and consolidate them into one model, the authors used consensus-based decision-making and a narrative thematic synthesis guided by several qualitative criteria. The authors subjected the model to external, independent review and improved upon its design with this feedback. Results The authors found seven LO frameworks particularly relevant to evidence-based practice innovations in organizations. The authors describe their interpretations of these frameworks for healthcare organizations, the process they used to integrate the LO frameworks with EBM principles, and the resulting Evidence in the Learning Organization (ELO model. They also provide a health organization scenario to illustrate ELO concepts in application. Conclusion The authors intend, by sharing the LO frameworks and the ELO model, to help organizations identify their capacities to learn and share knowledge about evidence-based practice

  4. Scientific Evidence for Hydrostatic Shock

    CERN Document Server

    Courtney, Michael

    2008-01-01

    This paper reviews the scientific support for a ballistic pressure wave radiating outward from a penetrating projectile and causing injury and incapacitation. This phenomenon is known colloquially as "hydrostatic shock." The idea apparently originates with Col. Frank Chamberlin, a World War II trauma surgeon and wound ballistics researcher. The paper reviews claims that hydrostatic shock is a myth and considers supporting evidence through parallels with blast, describing the physics of the pressure wave, evidence for remote cerebral effects, and remote effects in the spine and other internal organs. Finally, the review considers the levels of energy transfer required for the phenomenon to be readily observed.

  5. Evidence on global medical travel.

    Science.gov (United States)

    Ruggeri, Kai; Záliš, Ladislav; Meurice, Christopher R; Hilton, Ian; Ly, Terry-Lisa; Zupan, Zorana; Hinrichs, Saba

    2015-11-01

    The potential benefits of travelling across national borders to obtain medical treatment include improved care, decreased costs and reduced waiting times. However, medical travel involves additional risks, compared to obtaining treatment domestically. We review the publicly-available evidence on medical travel. We suggest that medical travel needs to be understood in terms of its potential risks and benefits so that it can be evaluated against alternatives by patients who are seeking care. We propose three domains -quality standards, informed decision-making, economic and legal protection - in which better evidence could support the development of medical travel policies. PMID:26549906

  6. The Notion of Evidence in Evidence-Based Practice by the Nursing Philosophy Working Group.

    Science.gov (United States)

    Romyn, Donna M.; Allen, Marion N.; Boschma, Geertje; Duncan, Susan M.; Edgecombe, Nancy; Jensen, Louise A.; Ross-Kerr, Janet C.; Marck, Patricia; Salsali, Mahvash; Tourangeau, Ann E.; Warnock, Fay

    2003-01-01

    Addresses these questions: To what end is evidence sought? What is the nature of evidence? What kinds of evidence are valued by the nursing profession? and What kinds of evidence should underlie clinical decision making? (Contains 28 references.) (SK)

  7. Multiple sclerosis: evidence and controversies

    OpenAIRE

    Ángela María Gutiérrez-Álvarez

    2006-01-01

    Introduction: Multiple sclerosis is a chronicrecurrent inflammatory disorder of the centralnervous system. The pharmacological treatmentof multiple sclerosis has been evaluated withmultiple controlled clinical trials that allow theclinician to count with evidence based informationto decide the more indicated treatmentfor each patient.Methodology: A review of the scientific literaturewas conducted to clarify controversialissues in a clinical relevant topic.Development: The diagnostic criteria ...

  8. Evidence-Based IT Development

    DEFF Research Database (Denmark)

    Simonsen, Jesper; Hertzum, Morten

    2005-01-01

    Evidence-based IT development aims at developing a new commercial contract model for IT projects where the cus-tomers payment is dependent on measurable effects of using the vendors system. The idea is to establish a strategic part-nership in which customer and IT vendor share the responsi-bility...

  9. Voluntary disclosure: Evidence from UK

    NARCIS (Netherlands)

    N.S. Zourarakis (Nicolaos)

    2009-01-01

    textabstractThis paper investigates the voluntary disclosure of Intellectual Capital (IC) of British firms and provides some evidence on an unexplored area of the literature; that of the association of Corporate Governance (CG) with IC disclosure. Inconsistent with expectations, the results show tha

  10. From evidence-based to evidence-reflected practice

    DEFF Research Database (Denmark)

    Lystbæk, Christian Tang

    “Knowledge” is of the utmost significance for professional practice and learning. Today, though, the established knowledge base is changing in all areas of the labour market (Alvesson, 2004). Work and society are dominated by commitment to demands for high levels of demonstrable accountability...... of a thing, a situation, an action, or something else, and judgments involves criteria, either explicit or implicit criteria. Thus, the Wittgensteinian approach I take suggests a more interpretative, reasoning approach, one that is sensitive to ambiguity, incoherence, multiple meanings and contradiction...... within professional practice and learning. Hence, it suggest the need to move beyond current ideas of an evidence-based practice towards a conception of an evidence-reflected practice in which professional knowledge is regarded not as a fixed base, but as a field of ambiguity and multiple meanings which...

  11. Evidence-Based Radiology (EBR

    Directory of Open Access Journals (Sweden)

    Mansoor Fatehi

    2009-01-01

    Full Text Available   "nRecent increase in scientific advancements has led to inability to cover many scientific data and remain “up-to-date”. Nowadays doubling time of scientific data production is remarkably reduced, so that there is no adequate time to find this information and it seems inevitable to use resources which periodically assess most published papers or web-based data in that particular field to finally provide evidence-based knowledge, namely “Evidence-Based Medicine (EBM” in medical sciences. EBM is the systematic, scientific and explicit use of current best evidence in making decisions about the care of individual patients. Medical practice is largely based on clinical anecdotes, uncontrolled investigations and expert opinion. In radiology, the situation is especially problematic. "nRadiologists require to be able to evaluate studies in the literature, i.e., how reliable is this information and does it apply to patients in the radiologist’s practice? "nWe may find that our textbooks are out of date, guidelines are non-specific and there are conflicting "nor unreliable reports in the literature. Expert opinions vary from centre to centre. "nWhen we go to the literature ourselves, the first problem we encounter is the volume of literature being published and the next (at least for most of us is lack of training in how to separate good studies from weak ones. Evidence-based radiology (EBR can be a solution. "nThere are 5 steps in applying an approach as a solution: "n1. Ask - Information needs relevant to individual patients are converted into ‘answerable’ or ‘focused’ questions. "n2. Search - A comprehensive literature search is performed to find the best evidence to help answer these questions. "n3. Appraise - The evidence must then be critically appraised, in an explicit and structured manner, in order to establish its validity, reliability and usefulness in practice. "n4. Apply - The results of this critical appraisal are then

  12. 45 CFR 501.6 - Documentary evidence.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Documentary evidence. 501.6 Section 501.6 Public... Documentary evidence. Documentary evidence may consist of books, records, correspondence or other documents..., correspondence or other documents sought. The production of documentary evidence will not be required at...

  13. 22 CFR 51.41 - Documentary evidence.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Documentary evidence. 51.41 Section 51.41 Foreign Relations DEPARTMENT OF STATE NATIONALITY AND PASSPORTS PASSPORTS Evidence of U.S. Citizenship or Nationality § 51.41 Documentary evidence. The applicant must provide documentary evidence that he or she is...

  14. 43 CFR 35.34 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Evidence. 35.34 Section 35.34 Public Lands... STATEMENTS § 35.34 Evidence. (a) The ALJ shall determine the admissibility of evidence. (b) Except as provided in this part, the ALJ shall not be bound by the Federal Rules of Evidence. However, the ALJ...

  15. 45 CFR 672.15 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Evidence. 672.15 Section 672.15 Public Welfare... PROCEDURES § 672.15 Evidence. (a) General. The Presiding Officer shall admit all evidence which is not.... Notwithstanding the preceding sentence, evidence relating to settlement which would be excluded in the...

  16. 17 CFR 10.67 - Evidence.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Evidence. 10.67 Section 10.67... Evidence. (a) Admissibility. Relevant, material and reliable evidence shall be admitted. Irrelevant, immaterial, unreliable and unduly repetitious evidence shall be excluded. (b) Official notice. (1)...

  17. 14 CFR 13.59 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Evidence. 13.59 Section 13.59 Aeronautics... AND ENFORCEMENT PROCEDURES Rules of Practice for FAA Hearings § 13.59 Evidence. (a) Each party to a hearing may present the party's case or defense by oral or documentary evidence, submit evidence...

  18. 21 CFR 17.39 - Evidence.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Evidence. 17.39 Section 17.39 Food and Drugs FOOD... HEARINGS § 17.39 Evidence. (a) The presiding officer shall determine the admissibility of evidence. (b... Evidence.” However, the presiding officer may apply the “Federal Rules of Evidence” when appropriate,...

  19. 20 CFR 901.45 - Evidence.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Evidence. 901.45 Section 901.45 Employees... § 901.45 Evidence. (a) In general. The rules of evidence prevailing in courts of law and equity are not... actuaries. However, the Administrative Law Judge shall exclude evidence which is irrelevant, immaterial,...

  20. 37 CFR 11.50 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Evidence. 11.50 Section 11.50... Proceedings; Jurisdiction, Sanctions, Investigations, and Proceedings § 11.50 Evidence. (a) Rules of evidence. The rules of evidence prevailing in courts of law and equity are not controlling in hearings...

  1. 40 CFR 27.34 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Evidence. 27.34 Section 27.34... Evidence. (a) The presiding officer shall determine the admissibility of evidence. (b) Except as provided in this part, the presiding officer shall not be bound by the Federal Rules of Evidence. However,...

  2. 22 CFR 18.16 - Evidence.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Evidence. 18.16 Section 18.16 Foreign Relations... Enforcement Proceedings § 18.16 Evidence. The rules of evidence prevailing in courts of law and equity are not controlling in hearings under this part. However, the hearing examiner shall exclude evidence which...

  3. 8 CFR 244.9 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Evidence. 244.9 Section 244.9 Aliens and... OF DESIGNATED STATES § 244.9 Evidence. (a) Documentation. Applicants shall submit all documentation... affidavit or other credible evidence may be submitted. (1) Evidence of identity and nationality....

  4. 16 CFR 1025.43 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Evidence. 1025.43 Section 1025.43 Commercial... § 1025.43 Evidence. (a) Applicability of Federal Rules of Evidence. Unless otherwise provided by statute or these rules, the Federal Rules of Evidence shall apply to all proceedings held pursuant to...

  5. 49 CFR 511.43 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 6 2010-10-01 2010-10-01 false Evidence. 511.43 Section 511.43 Transportation..., DEPARTMENT OF TRANSPORTATION ADJUDICATIVE PROCEDURES Hearings § 511.43 Evidence. (a) Applicability of Federal Rules of Evidence. The Federal Rules of Evidence shall apply to proceedings held under this part only...

  6. 31 CFR 360.23 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Evidence. 360.23 Section 360.23 Money... BONDS, SERIES I Judicial Proceedings § 360.23 Evidence. (a) General. To establish the validity of... must be supported by appropriate evidence of appointment and qualification. The evidence must...

  7. 31 CFR 315.23 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Evidence. 315.23 Section 315.23 Money... Caveats Permitted § 315.23 Evidence. (a) General. To establish the validity of judicial proceedings... supported by appropriate evidence of appointment and qualification. The evidence must be certified by...

  8. 42 CFR 422.1048 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Evidence. 422.1048 Section 422.1048 Public Health... PROGRAM MEDICARE ADVANTAGE PROGRAM Appeal procedures for Civil Money Penalties § 422.1048 Evidence. Evidence may be received at the hearing even though inadmissible under the rules of evidence applicable...

  9. 42 CFR 423.659 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Evidence. 423.659 Section 423.659 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE....659 Evidence. The hearing officer rules on the admissibility of evidence and may admit evidence...

  10. 5 CFR 831.1109 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Evidence. 831.1109 Section 831.1109...) RETIREMENT Prohibition on Payments of Annuities § 831.1109 Evidence. (a) Rules of evidence are not strictly applied, but the presiding officer shall exclude irrelevant or unduly repetitious evidence. (b)...

  11. 10 CFR 2.711 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Evidence. 2.711 Section 2.711 Energy NUCLEAR REGULATORY... Adjudications § 2.711 Evidence. (a) General. Every party to a proceeding has the right to present oral or documentary evidence and rebuttal evidence and to conduct, in accordance with an approved...

  12. 31 CFR 15.737-21 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Evidence. 15.737-21 Section 15.737-21... Administrative Enforcement Proceedings § 15.737-21 Evidence. (a) In general. The rules of evidence prevailing in... exclude evidence which is irrelevant, immaterial, or unduly repetitious. (b) Depositions. The...

  13. 24 CFR 180.620 - Evidence.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Evidence. 180.620 Section 180.620 Housing and Urban Development Regulations Relating to Housing and Urban Development OFFICE OF ASSISTANT... Evidence. The Federal Rules of Evidence apply to the presentation of evidence in hearings under this part....

  14. 14 CFR 406.149 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Evidence. 406.149 Section 406.149... Transportation Adjudications § 406.149 Evidence. (a) General. A party is entitled to present the party's case or defense by oral, documentary, or demonstrative evidence, to submit rebuttal evidence, and to conduct...

  15. 45 CFR 1386.105 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Evidence. 1386.105 Section 1386.105 Public Welfare... § 1386.105 Evidence. (a) Testimony. Testimony by witnesses at the hearing is given orally under oath or... hearing if the presiding officer requires it. (c) Rules of evidence. Technical rules of evidence do...

  16. 34 CFR 81.15 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Evidence. 81.15 Section 81.15 Education Office of the... Evidence. (a) The Federal Rules of Evidence do not apply to proceedings under this part. However, the ALJ accepts only evidence that is— (1) Relevant; (2) Material; (3) Not unduly repetitious; and (4)...

  17. 37 CFR 351.10 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Evidence. 351.10 Section 351... JUDGES RULES AND PROCEDURES PROCEEDINGS § 351.10 Evidence. (a) Admissibility. All evidence that is... authenticated or identified in order to be admissible as evidence. The requirement of authentication...

  18. 14 CFR 13.222 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Evidence. 13.222 Section 13.222 Aeronautics... AND ENFORCEMENT PROCEDURES Rules of Practice in FAA Civil Penalty Actions § 13.222 Evidence. (a... evidence, to submit rebuttal evidence, and to conduct any cross-examination that may be required for a...

  19. 49 CFR 821.38 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Evidence. 821.38 Section 821.38 Transportation... PRACTICE IN AIR SAFETY PROCEEDINGS Hearing § 821.38 Evidence. Each party shall have the right to present a case-in-chief, or defense, by oral and documentary evidence, to submit evidence in rebuttal, and...

  20. 39 CFR 959.17 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Evidence. 959.17 Section 959.17 Postal Service... STATUTES § 959.17 Evidence. (a) Except as otherwise provided in these rules, the rules of evidence... repetitious evidence. (b) Testimony shall be under oath or affirmation and witnesses shall be subject to...

  1. 29 CFR 511.13 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Evidence. 511.13 Section 511.13 Labor Regulations Relating... AMERICAN SAMOA § 511.13 Evidence. In accordance with the notice of hearing, the committee and any... they are not refuted by evidence received at the hearing. Other pertinent evidence available to...

  2. Evidence-Based Practice and School Nursing

    Science.gov (United States)

    Adams, Susan; McCarthy, Ann Marie

    2005-01-01

    School nurses need to demonstrate that their practice is based on the best evidence available, which is usually data obtained from research. Evidence-based practice involves combining the best evidence available with nursing expertise and patient and family preferences to determine optimum care. Evidence-based practice guidelines are developed by…

  3. Experimental Evidence on Transfer Pricing

    Directory of Open Access Journals (Sweden)

    Tran Quoc H.

    2016-06-01

    Full Text Available We use incentivized economics experiments to test both the point predictions and comparative static predictions of optimal transfer pricing models, comparing behavior under varying conditions, including wholly versus partially-owned subsidiaries and different tariff and tax rates. As predicted, we find that transfer prices are responsive to relative tax and tariff rates as well as ownership proportions. Additionally, we examine convergence and learning in this setting. While individuals do not choose optimal transfer prices, their choices converge to optimal levels with experience. This paper thus makes two important contributions. First, by comparing behavior with theoretical predictions it provides evidence of whether (and when individuals set transfer prices optimally. Second, by comparing behavior under conditions of full and partial ownership it provides evidence on the impact of policy interventions (like regulating ownership proportions by MNEs on tax revenues.

  4. Evidence, Ethics & Social Policy Dilemmas

    Directory of Open Access Journals (Sweden)

    Steven I. Miller

    1993-07-01

    Full Text Available Within the philosophy of the social sciences, the relationship between evidence, ethics, and social policy is in need of further analysis. The present paper is an attempt to argue that while important social policies can, and perhaps ought to be, grounded in ethical theory, they are seldom articulated in this fashion due to the ambiguity surrounding the "evidence condition." Using a consequentialist-utilitarian framework, and a case study of a policy dilemma, the authors analyze the difficulties associated with resolving policy-based dilemmas which must appeal to evidential support as a justification for an ethical stand. Implication for the relevance of ethics to social policy formulation are discussed in detail.

  5. Evidence of improved inventory control

    OpenAIRE

    Dan M. Bechter; Stephen Stanley

    1992-01-01

    Inventory data applied to a standard partial stock-adjustment model demonstrate that inventory control, defined by desired marginal inventory-sales ratios and speeds of adjustment, improved in the last decade or so, particularly in the manufacturing sector. In addition, the evidence suggests that, contrary to popular wisdom, the net effect of these changes in inventory control has been to increase the volatility of inventory investment in both the manufacturing and trade sectors.

  6. Hard Evidence on Soft Skills

    OpenAIRE

    Heckman, James J.; Kautz, Tim

    2012-01-01

    This paper summarizes recent evidence on what achievement tests measure; how achievement tests relate to other measures of "cognitive ability" like IQ and grades; the important skills that achievement tests miss or mismeasure, and how much these skills matter in life. Achievement tests miss, or perhaps more accurately, do not adequately capture, soft skills--personality traits, goals, motivations, and preferences--that are valued in the labor market, in school, and in many other domains. The ...

  7. Insurance and liquidity : panel evidence

    OpenAIRE

    Shankar, Rashmi

    2005-01-01

    The author presents evidence that balance sheet effects are critical determinants of both the likelihood of a crisis and of income losses following a crisis. She tests the validity of "insurance" and "liquidity" models of currency crisis. Both models predict that the occurrence of a balance of payments crisis is conditional on the health of the nation's accounts in relation to the rest of the world. Problems in the balance sheet either cause a financial crisis that develops into a run on the ...

  8. Evidence on global medical travel

    OpenAIRE

    Ruggeri, Kai; Záliš, Ladislav; Meurice, Christopher R; Hilton, Ian; Ly, Terry-Lisa; Zupan, Zorana; Hinrichs, Saba

    2015-01-01

    Abstract The potential benefits of travelling across national borders to obtain medical treatment include improved care, decreased costs and reduced waiting times. However, medical travel involves additional risks, compared to obtaining treatment domestically. We review the publicly-available evidence on medical travel. We suggest that medical travel needs to be understood in terms of its potential risks and benefits so that it can be evaluated against alternatives by patients who are seeking...

  9. Scientific Evidence for Hydrostatic Shock

    OpenAIRE

    Courtney, Michael; Courtney, Amy

    2008-01-01

    This paper reviews the scientific support for a ballistic pressure wave radiating outward from a penetrating projectile and causing injury and incapacitation. This phenomenon is known colloquially as "hydrostatic shock." The idea apparently originates with Col. Frank Chamberlin, a World War II trauma surgeon and wound ballistics researcher. The paper reviews claims that hydrostatic shock is a myth and considers supporting evidence through parallels with blast, describing the physics of the pr...

  10. Clean Evidence on Peer Pressure

    OpenAIRE

    Falk, Armin; Ichino, Andrea

    2003-01-01

    While confounding factors typically jeopardize the possibility of using observational data to measure peer effects, field experiments over the potential for obtaining clean evidence. In this paper we measure the output of subjects who were asked to stuff letters into envelopes, with a remuneration completely independent of output. We study two treatments. In the 'pair' treatment two subjects work at the same time in the same room. Peer effects are possible in this situation and imply that out...

  11. Observational Evidence for Black Holes

    OpenAIRE

    Narayan, Ramesh; McClintock, Jeffrey E.

    2013-01-01

    Astronomers have discovered two populations of black holes: (i) stellar-mass black holes with masses in the range 5 to 30 solar masses, millions of which are present in each galaxy in the universe, and (ii) supermassive black holes with masses in the range 10^6 to 10^{10} solar masses, one each in the nucleus of every galaxy. There is strong circumstantial evidence that all these objects are true black holes with event horizons. The measured masses of supermassive black hole are strongly corr...

  12. Proof of evidence [BNFL 2

    International Nuclear Information System (INIS)

    It is shown that the fuel cycle requirements of the proposed Sizewell B nuclear power station could be supplied by British Nuclear Fuels Limited. It is demonstrated that any facilities which may be required in the future could be provided from established technology. Evidence is presented in support of the responses which the Company has made to requests from the CEGB for guidance on the charges it should assume for some fuel cycle services in a variety of circumstances. Reference is made throughout to the fuel cycle needs of other possible future nuclear power stations as postulated by CEGB in its Statement of Case. (U.K.)

  13. Evidence for a nonplanar amplituhedron

    Science.gov (United States)

    Bern, Zvi; Herrmann, Enrico; Litsey, Sean; Stankowicz, James; Trnka, Jaroslav

    2016-06-01

    The scattering amplitudes of planar mathcal{N} = 4 super-Yang-Mills exhibit a number of remarkable analytic structures, including dual conformal symmetry and logarithmic singularities of integrands. The amplituhedron is a geometric construction of the integrand that incorporates these structures. This geometric construction further implies the amplitude is fully specified by constraining it to vanish on spurious residues. By writing the amplitude in a dlog basis, we provide nontrivial evidence that these analytic properties and "zero conditions" carry over into the nonplanar sector. This suggests that the concept of the amplituhedron can be extended to the nonplanar sector of mathcal{N} = 4 super-Yang-Mills theory.

  14. Leading teaming: Evidence from Jazz

    OpenAIRE

    Araújo, Francisco Maria Trigo da Roza Carvalho

    2013-01-01

    A Work Project, presented as part of the requirements for the Award of a Masters Degree in Management from the NOVA – School of Business and Economics In this research we conducted qualitative analysis to study the team dynamics of jazz combos in order to explore deeper the leadership behaviors in a creative environment where teaming occurs. We found evidence of a dual leader, one that shifts his/her role between ‘leader as leader’ and ‘leader as member’, embracing both leaderfulness an...

  15. Conditionally Optimal Weights of Evidence

    Institute of Scientific and Technical Information of China (English)

    Stephan Morgenthaler; Robert G. Staudte

    2005-01-01

    A weight of evidence is a calibrated statistic whose wlues in [0, 1] indicate the degree of agreement between the data and either of two hypothesis, one being treated as the null (H0) and the other as the alternative (H1). A wlue of zero means perfect agreement with the null, whereas a value of one means perfect agreement with the alternative. The optimality we consider is minimal mean squared error (MSE) under the alternative while keeping the MSE under the null below a fixed bound. This paper studies such statistics from a conditional point of view, in particular for location and scale models.

  16. Digital forensics digital evidence in criminal investigations

    CERN Document Server

    Marshall, Angus McKenzie

    2009-01-01

    The vast majority of modern criminal investigations involve some element of digital evidence, from mobile phones, computers, CCTV and other devices. Digital Forensics: Digital Evidence in Criminal Investigations provides the reader with a better understanding of how digital evidence complements "traditional" scientific evidence and examines how it can be used more effectively and efficiently in a range of investigations. Taking a new approach to the topic, this book presents digital evidence as an adjunct to other types of evidence and discusses how it can be deployed effectively in s

  17. Index effects: Evidence from Australia

    Directory of Open Access Journals (Sweden)

    Zhao R

    2016-04-01

    Full Text Available This paper presents the findings of the first study of the index effects from changes in the composition of Australia’s tradeable benchmark index: the S&P/ASX 200. Prior to the introduction of the S&P/ASX200 changes to the composition of the market’s (then benchmark index (the All Ordinaries Index became evident before the formal announcement dates and the changes were made the following trading day. These announcement arrangements enabled profitable front-running trading. Along with the introduction of the new indices (including the S&P/ASX200 the arrangements for announcing changes to the composition of the index were changed to remove the opportunity for profitable frontrunning trading. While this objective was largely met for additions to the index the study found statistically significant evidence of price pressure between the announcement and implementation dates which were partially offset over the subsequent 20-day period. In relation to deletions the study found negative abnormal returns prior to announcement dates as well as between the announcement and implementation dates that were partially reversed over the subsequent 20-day period. The overall conclusion is that the event of changes in the composition of the S&P/ASX200 is on average associated with positive abnormal returns for additions and negative abnormal returns for deletions.

  18. Early warning systems - empirical evidence

    Directory of Open Access Journals (Sweden)

    Davor Labaš

    2012-12-01

    Full Text Available Despite the importance of early warning systems (EWS in revealing weak signals on environmental changes and in constructing a solid base for timely and appropriate business response, particularly against the backdrop of business crises, empirical evidence - especially at the country level - still lags behind. The aim of this paper is to contribute to the practical and theoretical knowledge about EWS by providing empirical evidence from companies located in three different European countries, i.e. Croatia, Austria and Greece. We propose that companies in richer countries, as measured in terms of GDP, have a higher implementation level of EWS and are more likely to meet current state-of-the-art EWS standards while companies in the countries with a lower GDP show a lesser level of development. Moreover, we explore the reasons for not implementing EWS. For our survey we used a structured questionnaire. Contrary to our hypotheses, there are no significant differences among the countries concerning the level of EWS implementation. However, there are some differences as to the kind of EWS. Overall, EWS are predominately short-term oriented and operating in all three countries. The main reasons for not implementing EWS are the shortage of employees and the lack of management initiatives.

  19. Science and evidence: separating fact from fiction.

    Science.gov (United States)

    Hess, Dean R

    2013-10-01

    Evidence-based medicine (EBM) is the integration of individual clinical expertise with the best available research evidence from systematic research and the patient's values and expectations. A hierarchy of evidence can be used to assess the strength upon which clinical decisions are made. The efficient approach to finding the best evidence is to identify systematic reviews or evidence-based clinical practice guidelines. Respiratory therapies that evidence supports include noninvasive ventilation for appropriately selected patients, lung-protective ventilation, and ventilator discontinuation protocols. Evidence does not support use of weaning parameters, albuterol for ARDS, and high frequency oscillatory ventilation for adults. Therapy with equivocal evidence includes airway clearance, selection of an aerosol delivery device, and PEEP for ARDS. Although all tenets of EBM are not universally accepted, the principles of EBM nonetheless provide a valuable approach to respiratory care practice.

  20. More Evidence That Zika Causes Microcephaly

    Science.gov (United States)

    ... https://medlineplus.gov/news/fullstory_160978.html More Evidence That Zika Causes Microcephaly Study of Brazilian newborns ... Lancet Infectious Diseases , seems to offer even clearer evidence, its authors said. The research involved 30 babies ...

  1. ON EVIDENCE: APPROACH FROM THE PHILOSOPHICAL HERMENEUTICS

    Directory of Open Access Journals (Sweden)

    Arturo García Rillo

    2015-06-01

    Full Text Available In order to make the term analytical evidence to reveal the original meaning of its application to account for hermeneutical situations in the world of life, the study was conducted from philosophical hermeneutics stating the following: viewpoint, understanding horizon and fusion of horizons. In the viewpoint uses of evidence are described. The horizon of understanding traces the history of the concept of evidence highlighting the perspective of Husserl. In the fusion of horizons evidence described in three levels of reality: perceived (evidence from beliefs, known (evidence from knowledge and constructed (deliberative evidence. We conclude that the historicity of the world allows rehabilitate the tradition and gives meaning to the evidence as the fact that it gets in the eyes through the original experience of hermeneutics situation that exists in practice.

  2. 24 CFR 26.47 - Evidence.

    Science.gov (United States)

    2010-04-01

    ... PROCEDURES Hearings Pursuant to the Administrative Procedure Act Hearings § 26.47 Evidence. The ALJ shall... evidence if its probative value is substantially outweighed by confusion of the issues, or...

  3. The Ethical Use of Evidence in Biomedicine.

    Science.gov (United States)

    Pellegrino, Edmund D.

    1999-01-01

    Examines the ethics of data collection and dissemination, suggesting criteria for the morally responsible treatment of evidence collection, dissemination, and use. Comments on the importance of V. Mike's proposal of an "ethics of evidence." (SLD)

  4. Modeling Forensic Evidence Systems Using Design Science

    OpenAIRE

    Armstrong, Colin; Armstrong, Helen

    2010-01-01

    This paper presents an overview of the application of design science research to the tactical management of forensic evidence processing. The opening discussion addresses the application of design science techniques to specific socio-technical information systems research in regard to processing forensic evidence. The discussion then presents the current problems faced by those dealing with evidence and a conceptual meta-model for a unified approach to forensic evidence is developed. Any prac...

  5. Evidence-Based Practice: Management of Vertigo

    OpenAIRE

    Nguyen-Huynh, Anh T.

    2012-01-01

    The article focuses on the evidence basis for the management of benign paroxysmal positional vertigo (BPPV), the most common diagnosis of vertigo in both primary care and subspecialty settings. Like all articles in this compilation of evidence-based practice, an overview is presented along with evidence based clinical assessment, diagnosis, and management. Summaries of differential diagnosis of vertigo and outcomes are presented.

  6. 12 CFR 308.36 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Evidence. 308.36 Section 308.36 Banks and... PROCEDURE Uniform Rules of Practice and Procedure § 308.36 Evidence. (a) Admissibility. (1) Except as is otherwise set forth in this section, relevant, material, and reliable evidence that is not unduly...

  7. 5 CFR 842.804 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Evidence. 842.804 Section 842.804... Controllers § 842.804 Evidence. (a) An agency head's determination under § 842.803(a) (finding that a position...) must be based on the official position description and any other evidence deemed appropriate by...

  8. 12 CFR 509.36 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Evidence. 509.36 Section 509.36 Banks and... ADJUDICATORY PROCEEDINGS Uniform Rules of Practice and Procedure § 509.36 Evidence. (a) Admissibility. (1) Except as is otherwise set forth in this section, relevant, material, and reliable evidence that is...

  9. 38 CFR 18b.57 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Evidence. 18b.57 Section 18b.57 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) PRACTICE AND... § 18b.57 Evidence. Irrelevant, immaterial, unreliable, and unduly repetitious evidence will be excluded....

  10. 5 CFR 831.103 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Evidence. 831.103 Section 831.103...) RETIREMENT Administration and General Provisions § 831.103 Evidence. (a) Standard Form 2806 (Individual..., the department, agency, or OPM should request inferior or secondary evidence which is then admissible....

  11. 12 CFR 747.36 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Evidence. 747.36 Section 747.36 Banks and... Procedure § 747.36 Evidence. (a) Admissibility. (1) Except as is otherwise set forth in this section, relevant, material, and reliable evidence that is not unduly repetitive is admissible to the fullest...

  12. 8 CFR 1240.46 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Evidence. 1240.46 Section 1240.46 Aliens....46 Evidence. (a) Sufficiency. A determination of deportability shall not be valid unless it is found by clear, unequivocal, and convincing evidence that the facts alleged as grounds for deportation...

  13. 7 CFR 15.117 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Evidence. 15.117 Section 15.117 Agriculture Office of... and Administrative Review Under the Civil Rights Act of 1964 Hearing Procedures § 15.117 Evidence. Irrelevant, immaterial, unreliable, and unduly repetitious evidence will be excluded, and technical rules...

  14. 5 CFR 831.905 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Evidence. 831.905 Section 831.905...) RETIREMENT Law Enforcement Officers and Firefighters § 831.905 Evidence. (a) An agency head's determination... determination under § 831.904 must be based on the official position description and any other evidence...

  15. 13 CFR 134.223 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Evidence. 134.223 Section 134.223... OFFICE OF HEARINGS AND APPEALS Rules of Practice for Most Cases § 134.223 Evidence. (a) Federal Rules of Evidence. Unless contrary to a particular rule in this part, or an order of the Judge, the Federal Rules...

  16. 5 CFR 831.805 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Evidence. 831.805 Section 831.805...) RETIREMENT Nuclear Materials Couriers § 831.805 Evidence. (a) The Secretary of Energy's determination under... other evidence deemed appropriate by the agency head for making the determination. (c) If an employee...

  17. 19 CFR 210.37 - Evidence.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Evidence. 210.37 Section 210.37 Customs Duties... ADJUDICATION AND ENFORCEMENT Prehearing Conferences and Hearings § 210.37 Evidence. (a) Burden of proof. The.... (b) Admissibility. Relevant, material, and reliable evidence shall be admitted....

  18. 42 CFR 430.88 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Evidence. 430.88 Section 430.88 Public Health... Plans and Practice to Federal Requirements § 430.88 Evidence. (a) Evidentiary purpose. The hearing is directed to receiving factual evidence and expert opinion testimony related to the issues involved in...

  19. 40 CFR 209.26 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Evidence. 209.26 Section 209.26... Orders Issued Under Section 11(d) of the Noise Control Act § 209.26 Evidence. (a) The official... record. Evidence may be received at the hearing even though inadmissible under the rules of...

  20. 10 CFR 13.34 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Evidence. 13.34 Section 13.34 Energy NUCLEAR REGULATORY COMMISSION PROGRAM FRAUD CIVIL REMEDIES § 13.34 Evidence. (a) The ALJ shall determine the admissibility of evidence. (b) Except as provided in this part, the ALJ shall not be bound by the Federal Rules of...

  1. 12 CFR 19.36 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Evidence. 19.36 Section 19.36 Banks and Banking... Practice and Procedure § 19.36 Evidence. (a) Admissibility. (1) Except as is otherwise set forth in this section, relevant, material, and reliable evidence that is not unduly repetitive is admissible to...

  2. 49 CFR 211.75 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Evidence. 211.75 Section 211.75 Transportation... TRANSPORTATION RULES OF PRACTICE Interim Procedures for the Review of Emergency Orders § 211.75 Evidence. (a) The Federal Rules of Evidence for United States Courts and Magistrates shall be employed as general...

  3. 15 CFR 904.251 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Evidence. 904.251 Section 904.251... and Appeal Procedures Hearings § 904.251 Evidence. (a) In general. (1) At the hearing, every party has the right to present oral or documentary evidence in support of its case or defense, to...

  4. 49 CFR 31.34 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Evidence. 31.34 Section 31.34 Transportation Office of the Secretary of Transportation PROGRAM FRAUD CIVIL REMEDIES § 31.34 Evidence. (a) The ALJ shall determine the admissibility of evidence. (b) Except as provided in this part, the ALJ shall not...

  5. 22 CFR 35.34 - Evidence.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Evidence. 35.34 Section 35.34 Foreign Relations DEPARTMENT OF STATE CLAIMS AND STOLEN PROPERTY PROGRAM FRAUD CIVIL REMEDIES § 35.34 Evidence. (a) The ALJ shall determine the admissibility of evidence. (b) Except as provided herein, the ALJ shall not be...

  6. 34 CFR 101.78 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Evidence. 101.78 Section 101.78 Education Regulations... PRACTICE AND PROCEDURE FOR HEARINGS UNDER PART 100 OF THIS TITLE Hearing Procedures § 101.78 Evidence. Irrelevant, immaterial, unreliable, and unduly repetitious evidence will be excluded....

  7. Analysis of Reinforcement of Civil Evidence

    Institute of Scientific and Technical Information of China (English)

    Sun Xiaoyue

    2015-01-01

    Abstract:Corroborative evidence is the basis for ascertaining and corroboration rules are proof the rules, plays a corroborative proof function and limiting the discretion of judges. Full study of corroborative evidence in civil procedure rules to use, helps to perfect evidence rules of civil procedure and civil systems.

  8. 12 CFR 308.533 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Evidence. 308.533 Section 308.533 Banks and... PROCEDURE Program Fraud Civil Remedies and Procedures § 308.533 Evidence. (a) The ALJ will determine the admissibility of evidence. (b) Except as provided in this subpart, the ALJ will not be bound by the...

  9. 45 CFR 81.78 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Evidence. 81.78 Section 81.78 Public Welfare... 80 OF THIS TITLE Hearing Procedures § 81.78 Evidence. Irrelevant, immaterial, unreliable, and unduly repetitious evidence will be excluded....

  10. 49 CFR 1503.635 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Evidence. 1503.635 Section 1503.635 Transportation... Rules of Practice in TSA Civil Penalty Actions § 1503.635 Evidence. (a) General. A party is entitled to present the party's case or defense by oral, documentary, or demonstrative evidence, to submit...

  11. 31 CFR 353.23 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Evidence. 353.23 Section 353.23 Money... BONDS, SERIES EE AND HH Judicial Proceedings § 353.23 Evidence. (a) General. To establish the validity... insolvent's estate must be supported by appropriate evidence of appointment and qualification. The...

  12. 31 CFR 501.732 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Evidence. 501.732 Section 501.732... the Enemy Act (TWEA) Penalties § 501.732 Evidence. The applicable evidentiary standard for proceedings under this subpart is proof by a preponderance of reliable, probative, and substantial evidence....

  13. 45 CFR 79.34 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Evidence. 79.34 Section 79.34 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION PROGRAM FRAUD CIVIL REMEDIES § 79.34 Evidence. (a) The ALJ shall determine the admissibility of evidence. (b) Except as provided in this part,...

  14. 6 CFR 13.34 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Evidence. 13.34 Section 13.34 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY PROGRAM FRAUD CIVIL REMEDIES § 13.34 Evidence. (a) The ALJ will determine the admissibility of evidence. (b) Except as provided in this part, the...

  15. 12 CFR 263.36 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Evidence. 263.36 Section 263.36 Banks and... PRACTICE FOR HEARINGS Uniform Rules of Practice and Procedure § 263.36 Evidence. (a) Admissibility. (1) Except as is otherwise set forth in this section, relevant, material, and reliable evidence that is...

  16. 31 CFR 10.73 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Evidence. 10.73 Section 10.73 Money... SERVICE Rules Applicable to Disciplinary Proceedings § 10.73 Evidence. (a) In general. The rules of evidence prevailing in courts of law and equity are not controlling in hearings or proceedings...

  17. 14 CFR 77.57 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Evidence. 77.57 Section 77.57 Aeronautics... AFFECTING NAVIGABLE AIRSPACE Rules of Practice for Hearings Under Subpart D § 77.57 Evidence. (a) The... party to the hearing may object to the admission of evidence only on the ground that it is irrelevant....

  18. 41 CFR 50-203.18 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Evidence. 50-203.18...-Healey Public Contracts Act § 50-203.18 Evidence. (a) Witnesses appearing at the hearing need not be... shall be tendered in quadruplicate. When evidence is embraced in a document containing matter...

  19. 15 CFR 25.34 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Evidence. 25.34 Section 25.34 Commerce and Foreign Trade Office of the Secretary of Commerce PROGRAM Fraud Civil Remedies § 25.34 Evidence. (a) The ALJ shall determine the admissibility of evidence. (b) Except as provided in this part,...

  20. 8 CFR 315.3 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Evidence. 315.3 Section 315.3 Aliens and...: EXEMPTION FROM MILITARY SERVICE § 315.3 Evidence. (a) The records of the Selective Service System and the military department under which the alien served shall be conclusive evidence of whether the alien...

  1. 13 CFR 134.312 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Evidence. 134.312 Section 134.312 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION RULES OF PROCEDURE GOVERNING CASES BEFORE THE... Designations § 134.312 Evidence. To the extent the rules in this subpart permit the submission of evidence,...

  2. 5 CFR 842.905 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Evidence. 842.905 Section 842.905... EMPLOYEES RETIREMENT SYSTEM-BASIC ANNUITY Nuclear Materials Couriers § 842.905 Evidence. (a) The Secretary... official position description and any other evidence deemed appropriate by the agency head for making...

  3. 32 CFR 637.16 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Evidence. 637.16 Section 637.16 National Defense... INVESTIGATIONS MILITARY POLICE INVESTIGATION Investigations § 637.16 Evidence. Military police are authorized to receive, process, safeguard and dispose of evidence, to include non-narcotic controlled substances,...

  4. 43 CFR 4.452-6 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Evidence. 4.452-6 Section 4.452-6 Public... Fact § 4.452-6 Evidence. (a) All oral testimony shall be under oath and witnesses shall be subject to cross-examination. The administrative law judge may question any witness. Documentary evidence may...

  5. 43 CFR 4.835 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Evidence. 4.835 Section 4.835 Public Lands... Interior-Effectuation of Title VI of the Civil Rights Act of 1964 Hearing § 4.835 Evidence. Formal rules of evidence will not apply to the proceeding. Irrelevant, immaterial, unreliable, and unduly...

  6. 12 CFR 1780.51 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Evidence. 1780.51 Section 1780.51 Banks and....51 Evidence. (a) Admissibility. (1) Except as is otherwise set forth in this section, relevant, material and reliable evidence that is not unduly repetitive is admissible to the fullest extent...

  7. 43 CFR 4.435 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Evidence. 4.435 Section 4.435 Public Lands... Evidence. (a) All oral testimony shall be under oath and witnesses shall be subject to cross-examination. The administrative law judge may question any witnesses. Documentary evidence may be received...

  8. 42 CFR 93.208 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Evidence. 93.208 Section 93.208 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS... MISCONDUCT Definitions § 93.208 Evidence. Evidence means any document, tangible item, or testimony offered...

  9. 49 CFR 845.26 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Evidence. 845.26 Section 845.26 Transportation... PRACTICE IN TRANSPORTATION; ACCIDENT/INCIDENT HEARINGS AND REPORTS Conduct of Hearing § 845.26 Evidence. The chairman of the board of inquiry shall receive all testimony and evidence which may be of aid...

  10. 39 CFR 957.16 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Evidence. 957.16 Section 957.16 Postal Service... SUSPENSION FROM CONTRACTING § 957.16 Evidence. (a) Except as otherwise provided in the rules in this part, the rules of evidence governing civil proceedings in matters not involving trial by jury in the...

  11. 39 CFR 963.15 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Evidence. 963.15 Section 963.15 Postal Service... PANDERING ADVERTISEMENTS STATUTE, 39 U.S.C. 3008 § 963.15 Evidence. (a) In general, admissibility will hinge on relevancy and materiality. However, relevant evidence may be excluded if its probative value...

  12. 39 CFR 952.18 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Evidence. 952.18 Section 952.18 Postal Service... AND LOTTERY ORDERS § 952.18 Evidence. (a) Except as otherwise provided in these rules, the Federal Rules of Evidence shall govern. However, such rules may be relaxed to the extent that the...

  13. 39 CFR 964.10 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Evidence. 964.10 Section 964.10 Postal Service... DELIVERY PURSUANT TO 39 U.S.C. 3003, 3004 § 964.10 Evidence. (a) In general, admissibility will hinge on relevancy and materiality. However, relevant evidence may be excluded if its probative value...

  14. 21 CFR 1404.900 - Adequate evidence.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Adequate evidence. 1404.900 Section 1404.900 Food and Drugs OFFICE OF NATIONAL DRUG CONTROL POLICY GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Definitions § 1404.900 Adequate evidence. Adequate evidence means information sufficient...

  15. Using Science as Evidence in Public Policy

    Science.gov (United States)

    Prewitt, Kenneth, Ed.; Schwandt, Thomas A., Ed.; Straf, Miron L., Ed.

    2012-01-01

    "Using Science as Evidence in Public Policy" encourages scientists to think differently about the use of scientific evidence in policy making. This report investigates why scientific evidence is important to policy making and argues that an extensive body of research on knowledge utilization has not led to any widely accepted explanation…

  16. 5 CFR 185.126 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Evidence. 185.126 Section 185.126 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.126 Evidence. (a) The ALJ shall determine the admissibility of evidence. (b) Except as provided...

  17. Critical Dispositions: Evidence and Expertise in Education

    Science.gov (United States)

    Dimitriadis, Greg

    2011-01-01

    Set against the current proliferation of global "difference" and economic realignment, "Critical Dispositions" explores the notions of "evidence" and "expertise" in times of material scarcity. Both have come to the forefront of national and international debate in education as "evidence" and "evidence-based" research and pedagogical practices…

  18. Evidence-based practice voor verpleegkundigen

    NARCIS (Netherlands)

    Cox, C.M.M.; Louw, D.C.P. de; Verhoef, J.; Kuiper, C.

    2004-01-01

    Om goede en verantwoorde zorg te kunnen bieden, streeft de verpleegkundige naar evidence-based practice. Evidence-based practice is het gewetensvol, expliciet en oordeelkundig gebruik van het huidige beste bewijsmateriaal om beslissingen te nemen voor individuele patiënten. De praktijk van evidence-

  19. Evidence-based Science Communication

    Science.gov (United States)

    Kahan, D.

    2012-12-01

    This presentation will describe a concrete strategy for bridging the gap between the *science* of science communication and the practice of it. In recent years, social scientists have made substantial progress in identifying the psychological influences that shape public receptivity to scientific information relating to climate change and other public policy issues. That work, however, has consisted nearly entirely of laboratory experiments and public opinion surveys; these methods identify general mechanisms of information processing but do not yield concrete prescriptions for communication in field settings. In order to integrate the findings of the science of science communication with the practice of it, field communication must now be made into a meaningful site of science communication research. "Evidence-based science communication" will involve collaborative work between social scientists and practitioners aimed at formulating and testing scientifically informed communication strategies in real-world contexts.

  20. Reconsidering Subextraction: Evidence from Spanish

    Directory of Open Access Journals (Sweden)

    Ignacio Bosque

    2014-11-01

    Full Text Available This paper argues that so-called subextraction (e.g., Whoi has John seen a picture of ti ?; cf. Corver 2006 for recent discussion does not involve movement of a wh-phrase to a DP internal escape hatch position before reaching the CP layer. Instead, we claim that apparently subextracted wh-phrases are actually direct dependents of the verb after a process of reanalysis (or readjustment; cf. Chomsky 1977, Kayne 2002 applies. Our proposal rethinks an old (Bach & Horn 1976 idea, reframes it in modern terms and argues against the cyclic status of DPs (cf. Bruening 2009, Leu 2008, Ott 2008, and references therein, by leaning on new evidence from Spanish. The non-cyclic status of DPs is a fairly standard idea ever since clausal properties were assumed to hold for nominal domains (cf. Chomsky 1970, Brame 1982, Abney 1987, and much subsequent literature.

  1. Innovation Promises and Evidence Realities.

    Science.gov (United States)

    Maschke, Karen J

    2016-09-01

    Over the past year media outlets and scientific and bioethics journals have reported about several medical and scientific innovations touted as having the potential to fundamentally change not only how diseases and disorders are diagnosed and treated but even how to alter the genomes of future generations. The purported "miracle" blood-testing technology of Theranos and the potential use of the genome editing technology CRISPR-Cas9 to modify human and nonhuman organisms reflect dramatic advances in scientific understanding about the biological mechanisms of humans and other living organisms. Yet evidence about whether these and other innovative biomedical technologies are safe and effective and lead to improved health outcomes for patients young and old is often in dispute. How to assess the safety and effectiveness of innovative biomedical technologies, who should be involved in that effort, and how to define risks and benefits of those technologies are questions at the intersection of values, interests, and politics.

  2. Toxicological evidence in forensic pharmacology.

    Science.gov (United States)

    Ferner, R E

    2012-01-01

    Laboratory evidence of the presence and concentration of a drug in a person who has come to harm is often helpful in forensic pharmacology, and may be crucial. However, its value depends on two critical interpretations by the expert. First, the expert must make a careful analysis of the relationship between the results as measured in the sample and the drug in the patient at the time that harm occurred. That is especially difficult with post-mortem samples. Secondly, the expert must syntheses the laboratory information with the available clinical history and clinical or pathological findings. Even in the most favourable circumstances, when the sample is correctly obtained, identified, and analyzed, it can be hard to say that beyond reasonable doubt a given concentration had a given effect.

  3. Paleoseismology: evidence of earth activity

    Science.gov (United States)

    Nováková, Lucie

    2016-07-01

    The paleoseismic research aims to document earth activity during earthquakes, such as displacements of fault, rupture location, distribution of slip or ground shaking intensity. The earthquakes are usually distributed on the plate boundaries causing big damages of life on the Earth. Four faults in North America, New Zealand and Europe with different behaviour, direction and sense of movement have been chosen to document the seismic activity within the world. The White Creek Fault, the Greendale Fault, the San Andreas Fault and the Paganica Fault have been responsible for the earthquakes of M > 6 in the last century. Figures in this paper show the evidence of the earthquakes that can be visible in the field.

  4. The Evidence Regarding Maintenance Tocolysis

    Directory of Open Access Journals (Sweden)

    John P. Elliott

    2013-01-01

    Full Text Available Preterm delivery is a public health issue of major proportion. More than 12% of deliveries in the United States that occur at less than 37 weeks gestation preterm labor (PTL represents the largest single reason for preterm birth (PTB. Attempts to prevent PTB have been unsuccessful. This paper of maintenance tocolytic therapy will examine the efficacy and safety of the drugs, both oral and subcutaneous, which have been utilized for prolongation of pregnancy following successful arrest of a documented episode of acute preterm labor. The evidence for oral tocolytics as maintenance therapy as well as parenteral medications for such patients is offered. Finally, the effects in the United States of the Food and Drug Administration (FDA action on such medications are reported.

  5. Innovation Promises and Evidence Realities.

    Science.gov (United States)

    Maschke, Karen J

    2016-09-01

    Over the past year media outlets and scientific and bioethics journals have reported about several medical and scientific innovations touted as having the potential to fundamentally change not only how diseases and disorders are diagnosed and treated but even how to alter the genomes of future generations. The purported "miracle" blood-testing technology of Theranos and the potential use of the genome editing technology CRISPR-Cas9 to modify human and nonhuman organisms reflect dramatic advances in scientific understanding about the biological mechanisms of humans and other living organisms. Yet evidence about whether these and other innovative biomedical technologies are safe and effective and lead to improved health outcomes for patients young and old is often in dispute. How to assess the safety and effectiveness of innovative biomedical technologies, who should be involved in that effort, and how to define risks and benefits of those technologies are questions at the intersection of values, interests, and politics. PMID:27649835

  6. Taxonomic Evidence Applying Intelligent Information Taxonomic Evidence Applying Intelligent Information

    Directory of Open Access Journals (Sweden)

    Félix Anibal Vallejos

    2005-12-01

    Full Text Available The Numeric Taxonomy aims to group operational taxonomic units in clusters (OTUs or taxons or taxa, using the denominated structure analysis by means of numeric methods. These clusters that constitute families are the purpose of this series of projects and they emerge of the structural analysis, of their phenotypical characteristic, exhibiting the relationships in terms of grades of similarity of the OTUs, employing tools such as i the Euclidean distance and ii nearest neighbor techniques. Thus taxonomic evidence is gathered so as to quantify the similarity for each pair of OTUs (pair-group method obtained from the basic data matrix and in this way the significant concept of spectrum of the OTUs is introduced, being based the same one on the state of their characters. A new taxonomic criterion is thereby formulated and a new approach to Computational Taxonomy is presented, that has been already employed with reference to Data Mining, when apply of Machine Learning techniques, in particular to the C4.5 algorithms, created by Quinlan, the degree of efficiency achieved by the TDIDT family's algorithms when are generating valid models of the data in classification problems with the Gain of Entropy through Maximum Entropy Principle. The Numeric Taxonomy aims to group operational taxonomic units in clusters (OTUs or taxons or taxa, using the denominated structure analysis by means of numeric methods. These clusters that constitute families are the purpose of this series of projects and they emerge of the structural analysis, of their phenotypical characteristic, exhibiting the relationships in terms of grades of similarity of the OTUs, employing tools such as i the Euclidean distance and ii nearest neighbor techniques. Thus taxonomic evidence is gathered so as to quantify the similarity for each pair of OTUs (pair-group method obtained from the basic data matrix and in this way the significant concept of spectrum of the OTUs is introduced, being based

  7. The Electronic Evidence in Trial Proceedings

    Directory of Open Access Journals (Sweden)

    Monica Pocora

    2015-05-01

    Full Text Available This paper will consider theoretical and practical issues which arise in trial proceedings, throughout the virtual presence of persons involved. The EU Convention of 2000 provide the legal base for the use of video conference. In most jurisdictions, all forms of evidence is admissible, subject to rules relating to the exclusion of evidence because of improper actions or because the inclusion of the evidence would be unfair to the defendant. There is a difference between the admissibility of the evidence and laying the correct foundations before the evidence can be admitted.

  8. 29 CFR 18.402 - Relevant evidence generally admissible; irrelevant evidence inadmissible.

    Science.gov (United States)

    2010-07-01

    ... ADMINISTRATIVE HEARINGS BEFORE THE OFFICE OF ADMINISTRATIVE LAW JUDGES Rules of Evidence Relevancy and Its Limits § 18.402 Relevant evidence generally admissible; irrelevant evidence inadmissible. All relevant... 29 Labor 1 2010-07-01 2010-07-01 true Relevant evidence generally admissible; irrelevant...

  9. Imitation: definitions, evidence, and mechanisms.

    Science.gov (United States)

    Zentall, Thomas R

    2006-10-01

    Imitation can be defined as the copying of behavior. To a biologist, interest in imitation is focused on its adaptive value for the survival of the organism, but to a psychologist, the mechanisms responsible for imitation are the most interesting. For psychologists, the most important cases of imitation are those that involve demonstrated behavior that the imitator cannot see when it performs the behavior (e.g., scratching one's head). Such examples of imitation are sometimes referred to as opaque imitation because they are difficult to account for without positing cognitive mechanisms, such as perspective taking, that most animals have not been acknowledged to have. The present review first identifies various forms of social influence and social learning that do not qualify as opaque imitation, including species-typical mechanisms (e.g., mimicry and contagion), motivational mechanisms (e.g., social facilitation, incentive motivation, transfer of fear), attentional mechanisms (e.g., local enhancement, stimulus enhancement), imprinting, following, observational conditioning, and learning how the environment works (affordance learning). It then presents evidence for different forms of opaque imitation in animals, and identifies characteristics of human imitation that have been proposed to distinguish it from animal imitation. Finally, it examines the role played in opaque imitation by demonstrator reinforcement and observer motivation. Although accounts of imitation have been proposed that vary in their level of analysis from neural to cognitive, at present no theory of imitation appears to be adequate to account for the varied results that have been found. PMID:17024510

  10. Museums? Evidence from two Countries

    Directory of Open Access Journals (Sweden)

    Azilah Kasim

    2014-12-01

    Full Text Available This paper provides evidence on Young Adults’ motivations for visiting and not visiting museums. Using purposive sampling, self-administered questionnaires were distributed to respondents in Kedah, Malaysia and Eskisehir, Turkey. Both Kedah and Eskisehir share one similarity – they both have many museums. The findings revealed that in both study contexts, young people tended to visit museums for practical reasons such as to help them prepare homework or a project. They also visit for intrinsic reasons such as to satisfy their curiosity. Both samples also illustrate Davies (2001 contention that awareness is an important precursor to potential visits. On the other hand, both samples are different in reasons for not visiting. While young people in Eskisehir cite emotional reasons for deciding not to visit, young people in Kedah offered more practical ones such as lack of time and interest, or more interested in other activities. The study findings are useful for understanding reasons behind the generally low museum visits among youth. Several managerial implications of the study were also proposed.

  11. Imitation: definitions, evidence, and mechanisms.

    Science.gov (United States)

    Zentall, Thomas R

    2006-10-01

    Imitation can be defined as the copying of behavior. To a biologist, interest in imitation is focused on its adaptive value for the survival of the organism, but to a psychologist, the mechanisms responsible for imitation are the most interesting. For psychologists, the most important cases of imitation are those that involve demonstrated behavior that the imitator cannot see when it performs the behavior (e.g., scratching one's head). Such examples of imitation are sometimes referred to as opaque imitation because they are difficult to account for without positing cognitive mechanisms, such as perspective taking, that most animals have not been acknowledged to have. The present review first identifies various forms of social influence and social learning that do not qualify as opaque imitation, including species-typical mechanisms (e.g., mimicry and contagion), motivational mechanisms (e.g., social facilitation, incentive motivation, transfer of fear), attentional mechanisms (e.g., local enhancement, stimulus enhancement), imprinting, following, observational conditioning, and learning how the environment works (affordance learning). It then presents evidence for different forms of opaque imitation in animals, and identifies characteristics of human imitation that have been proposed to distinguish it from animal imitation. Finally, it examines the role played in opaque imitation by demonstrator reinforcement and observer motivation. Although accounts of imitation have been proposed that vary in their level of analysis from neural to cognitive, at present no theory of imitation appears to be adequate to account for the varied results that have been found.

  12. Mercury and autism: accelerating evidence?

    Science.gov (United States)

    Mutter, Joachim; Naumann, Johannes; Schneider, Rainer; Walach, Harald; Haley, Boyd

    2005-10-01

    The causes of autism and neurodevelopmental disorders are unknown. Genetic and environmental risk factors seem to be involved. Because of an observed increase in autism in the last decades, which parallels cumulative mercury exposure, it was proposed that autism may be in part caused by mercury. We review the evidence for this proposal. Several epidemiological studies failed to find a correlation between mercury exposure through thimerosal, a preservative used in vaccines, and the risk of autism. Recently, it was found that autistic children had a higher mercury exposure during pregnancy due to maternal dental amalgam and thimerosal-containing immunoglobulin shots. It was hypothesized that children with autism have a decreased detoxification capacity due to genetic polymorphism. In vitro, mercury and thimerosal in levels found several days after vaccination inhibit methionine synthetase (MS) by 50%. Normal function of MS is crucial in biochemical steps necessary for brain development, attention and production of glutathione, an important antioxidative and detoxifying agent. Repetitive doses of thimerosal leads to neurobehavioral deteriorations in autoimmune susceptible mice, increased oxidative stress and decreased intracellular levels of glutathione in vitro. Subsequently, autistic children have significantly decreased level of reduced glutathione. Promising treatments of autism involve detoxification of mercury, and supplementation of deficient metabolites.

  13. Evidence-based integrative dermatology

    Directory of Open Access Journals (Sweden)

    Saravu R Narahari

    2013-01-01

    Full Text Available American recognition for medical pluralism arrived in 1991. The National Center for Complementary and Alternative Medicine was established under the National Institutes of Health in 1998. Following this, patients and researchers began exploring use of integrative medicine. Terence Ryan with Gerry Bodeker in Europe, Brian Berman in America, and the Indian council of Medical Research advocated traditional medicine and integrative medicine. The Institute of Applied Dermatology (IAD, Kerala has developed integrated allopathic (biomedical and ayurvedic therapies to treat Lymphatic Filariasis, Lichen planus, and Vitiligo. Studies conducted at the IAD have created a framework for evidence-based and integrative dermatology (ID. This paper gives an overview of advances in ID with an example of Lichen Planus, which was examined jointly by dermatologists and Ayurveda doctors. The clinical presentation in these patients was listed in a vikruthi table of comparable biomedical terms. A vikruthi table was used for drug selection in ayurvedic dermatology. A total of 19 patients were treated with ayurvedic prescriptions to normalize the vatha-kapha for 3 months. All patients responded and no side effects were recorded. In spite of advancing knowledge on ID, several challenges remain for its use on difficult to treat chronic skin diseases. The formation of new integrative groups and financial support are essential for the growth of ID in India.

  14. The expression and interpretation of uncertain forensic science evidence: verbal equivalence, evidence strength, and the weak evidence effect.

    Science.gov (United States)

    Martire, Kristy A; Kemp, Richard I; Watkins, Ian; Sayle, Malindi A; Newell, Ben R

    2013-06-01

    Standards published by the Association of Forensic Science Providers (2009, Standards for the formulation of evaluative forensic science expert opinion, Science & Justice, Vol. 49, pp. 161-164) encourage forensic scientists to express their conclusions in the form of a likelihood ratio (LR), in which the value of the evidence is conveyed verbally or numerically. In this article, we report two experiments (using undergraduates and Mechanical Turk recruits) designed to investigate how much decision makers change their beliefs when presented with evidence in the form of verbal or numeric LRs. In Experiment 1 (N = 494), participants read a summary of a larceny trial containing inculpatory expert testimony in which evidence strength (low, moderate, high) and presentation method (verbal, numerical) varied. In Experiment 2 (N = 411), participants read the same larceny trial, this time including either exculpatory or inculpatory expert evidence that varied in strength (low, high) and presentation method (verbal, numerical). Both studies found a reasonable degree of correspondence in observed belief change resulting from verbal and numeric formats. However, belief change was considerably smaller than Bayesian calculations would predict. In addition, participants presented with evidence weakly supporting guilt tended to "invert" the evidence, thereby counterintuitively reducing their belief in the guilt of the accused. This "weak evidence effect" was most apparent in the verbal presentation conditions of both experiments, but only when the evidence was inculpatory. These findings raise questions about the interpretability of LRs by jurors and appear to support an expectancy-based account of the weak evidence effect.

  15. Defending Evidence Based Practice (Editorial

    Directory of Open Access Journals (Sweden)

    Lindsay Glynn

    2007-07-01

    contributing to the existing literature by publishing original research. One of the strengths of the EBLIP journal is the Evidence Summaries section. Not only are these critical appraisals of previously published research, but the critical appraisals themselves are peer reviewed. The knowledge base, therefore, is being populated with original research as well as rigorously evaluated research. Am I still feeling defensive? Perhaps a little. I am sure that the time and effort that I have invested in EBLIP cannot help but create some bias. On the other hand, I have seen that evidence based practice is making an impact on how numerous individuals and institutions approach decision making. I am reading, seeing and hearing about research being designed, performed and evaluated within a new framework. EBP is standard practice in the health professions and is swiftly gaining solid ground in the social sciences, education and in government. Our profession prides itself on being on the cutting edge of information access and management: if information professionals choose not to adopt the model, which has been proven time and time again to be effective, they risk being placed outside cutting edge, innovative practice. Is that where we want to be?

  16. Geological evidence of smectite longevity

    International Nuclear Information System (INIS)

    Search is going on for geological evidence of natural smectite clay materials that have been exposed to conditions that are similar to those radioactive in repositories. Cases in which heating to 90 degree C or more for long periods has taken place, are of particular interest. The report describes two bentonite layers, one of Miocenic age located at central Sardinia (Busachi), and the other of Ordovician age, forming a basal stratum of southern Gotland, (Hamra), Sweden. They both serve as excellent examples of the survival potential of montmorillonite-rich clays. The more than 10 m thick Sardinian bentonite bed was very significantly heated when the magma moved in and covered it. The upper meter was heated to more than 200 degree C for several days, while at more than 4 m depth, the temperature did note exceed 80 degree C. The test show that the smectite content was not reduced to less than 60 percent in any part of the layer sequence, while slight cementation was caused by precipitation of heat-released silica in the uppermost layer. The 0.3 m thick bed on Gotland is presently located at 515 m depth. Various investigations indicate that it has been exposed to an effective pressure of 300 MPa and a temperature of 110 degree C for several million years due to burial under almost 3 km of Devonian sediments. The content of smectite is around 25 percent of the bulk material, and 30-40 percent of the clay fraction. Illite appears to have been neoformed in small voids of the smectite matrix and the identified apparent I/S material is suggested to consist of mixed-layer minerals with hydrous mica and Ca or Na locked in instead of K, which would be the conventional interpretation. The earlier developed alteration model appears to be valid and it is extended in the present report on the basis of the findings. (28 illustrations, 9 tables)

  17. Evidence-Based ACL Reconstruction

    Directory of Open Access Journals (Sweden)

    E. Carlos RODRIGUEZ-MERCHAN

    2015-01-01

    Full Text Available There is controversy in the literature regarding a number of topics related to anterior cruciate ligament (ACLreconstruction. The purpose of this article is to answer the following questions: 1 Bone patellar tendon bone (BPTB reconstruction or hamstring reconstruction (HR; 2 Double bundle or single bundle; 3 Allograft or authograft; 4 Early or late reconstruction; 5 Rate of return to sports after ACL reconstruction; 6 Rate of osteoarthritis after ACL reconstruction. A Cochrane Library and PubMed (MEDLINE search of systematic reviews and meta-analysis related to ACL reconstruction was performed. The key words were: ACL reconstruction, systematic reviews and meta-analysis. The main criteria for selection were that the articles were systematic reviews and meta-analysesfocused on the aforementioned questions. Sixty-nine articles were found, but only 26 were selected and reviewed because they had a high grade (I-II of evidence. BPTB-R was associated with better postoperative knee stability but with a higher rate of morbidity. However, the results of both procedures in terms of functional outcome in the long-term were similar. The double-bundle ACL reconstruction technique showed better outcomes in rotational laxity, although functional recovery was similar between single-bundle and double-bundle. Autograft yielded better results than allograft. There was no difference between early and delayed reconstruction. 82% of patients were able to return to some kind of sport participation. 28% of patients presented radiological signs of osteoarthritis with a follow-up of minimum 10 years.

  18. INFLATION AND FINANCIAL DEVELOPMENT: EVIDENCE

    Directory of Open Access Journals (Sweden)

    Emmanuel Nii Abbey

    2012-01-01

    Full Text Available The study examined the impact of inflation on financial development in Ghana using quarterly time series data (1990-2008. It was in line with the empirical works that provided support for the proposition that inflation affects financial development negatively. While price stability has been emphasized in the literature to be the best antidote in addressing the problem, recent evidence of disagreements on its definition and the ways to achieving it, coupled with, threshold effects between the two variables have questioned the precise link between the two variables and their acclaimed antidote. The study therefore made use of the Cointegration Approach the Granger Causality testing procedure suggested and the Conditional Least Squares technique to address these issues for the case of Ghana. The study established several statistically significant and economically meaningful relationships between the two variables. Pair-wise correlation analysis established a negative association between the two variables. In contrast, conflicting results were produced with regression analysis: the relationship between the two variables in the short run was established to be positive, while no relationship at all was established in the long run. Furthermore, a unidirectional causal link was established to be running from inflation to financial development; when the ratio of private sector credit to GDP and the market capitalization ratio were used as indicators for financial development. Lastly, threshold effects were observed in the inflation-financial development relation for inflation rates between 11-16% per annum. The study thus recommended the definition of price stability for inflation rates between 11-16% in support of financial development in Ghana. Additionally, it was recommended that the country should promote financial sector policies in a more holistic approach, as financial development does not granger cause inflation or inflationary pressures.

  19. Evidence-Based ACL Reconstruction.

    Science.gov (United States)

    Rodriguez-Merchan, E Carlos

    2015-01-01

    There is controversy in the literature regarding a number of topics related to anterior cruciate ligament (ACL) reconstruction. The purpose of this article is to answer the following questions: 1) Bone-patellar tendon-bone reconstruction (BPTB-R) or hamstrimg reconstruction (H-R); 2) Double bundle or single bundle; 3) Allograft or authograft; 4) Early or late reconstruction; 5) Rate of return to sports after ACL reconstruction; 6) Rate of osteoarthritis after ACL reconstruction. A Cochrane Library and PubMed (MEDLINE) search of systematic reviews and meta-analysis related to ACL reconstruction was performed. The key words were: ACL reconstruction, systematic reviews and meta-analysis. The main criteria for selection were that the articles were systematic reviews and meta-analyses focused on the aforementioned questions. Sixty-nine articles were found, but only 26 were selected and reviewed because they had a high grade (I-II) of evidence. BPTB-R was associated with better postoperative knee stability but with a higher rate of morbidity. However, the results of both procedures in terms of functional outcome in the long-term were similar. The double-bundle ACL reconstruction technique showed better outcomes in rotational laxity, although functional recovery was similar between single-bundle and double-bundle. Autograft yielded better results than allograft. There was no difference between early and delayed reconstruction. 82% of patients were able to return to some kind of sport participation. 28% of patients presented radiological signs of osteoarthritis with a follow-up of minimum 10 years. PMID:25692162

  20. What is the Best Evidence Medical Education?

    Directory of Open Access Journals (Sweden)

    Rasoul Masoomi

    2012-07-01

    Full Text Available Best Evidence Medical Education (BEME is defined as: “The implementation by teachers and educational bodies in their practice, of methods and approaches to education based on the best evidence available.” Five steps have been recognized in the practice of BEME. These are: framing the question, developing a search strategy, evaluating the evidence, implementing change and evaluating that change. In this paper, I described the concept of BEME, its steps, and challenges.

  1. Compensation consultants and CEO pay: UK evidence

    OpenAIRE

    Voulgaris, Georgios; Stathopoulos, Konstantinos; Walker, Martin

    2010-01-01

    International audience Manuscript type: Empirical Research Question/ Issue: This paper provides new evidence on the effect of compensation consultants on CEO pay. Research Findings/ Insights: We produce new evidence on the managerial power approach (MPA) to corporate governance by examining the influence of compensation consultants on CEO pay structures and the decision to hire a compensation consultant in the UK. We find evidence that is not consistent with the MPA. Contrary to the MPA pr...

  2. Evidence Based Practice: Science? Or Art? (Editorial)

    OpenAIRE

    Denise Koufogiannakis

    2011-01-01

    Evidence based library and information practice (EBLIP) is a strategy to bridge research and practice. Generally EBLIP is seen as a movement to encourage and give practitioners the means to incorporate research into their practice, where it previously may have been lacking. The widely accepted definition of EBLIP (Booth, 2000) stresses three aspects that contribute to a practice that is evidence based: 1) "the best available evidence;" 2) "moderated by user needs and preferences;" 3) "applied...

  3. Evidence: To see or not to see.

    Science.gov (United States)

    Eriksson, Katie

    2010-10-01

    "To see or not to see" is an allusion to the classical Shakespearean quotation "to be or not to be, that is the question." Evidence as a concept pertains to truth, reality, and being in the world; it involves seeing, realizing, making visible, and clothing thoughts into words. A new interpretation of the concept of evidence in caring science is presented in this column, based on the etymology of the concept and Gadamer's hermeneutical philosophy. Ontological or absolute evidence is based on being and the true reality that extends beyond the immediate reality. The truth, or the substance, lies concealed within the true reality. Evidence includes envisioning, seeing, knowing, attesting, and revising.

  4. New evidence: Why flowers self-fertilize?

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    @@ Studies on some Himalayan Sginger flowers have contributed novel empirical evidence to Charles Darwin's self-pollination theory, according to CAS researchers from the Xishuangbanna Tropical Botanical Garden.

  5. Sicily statement on evidence-based practice

    Directory of Open Access Journals (Sweden)

    Hopayian Kevork

    2005-01-01

    Full Text Available Abstract Background A variety of definitions of evidence-based practice (EBP exist. However, definitions are in themselves insufficient to explain the underlying processes of EBP and to differentiate between an evidence-based process and evidence-based outcome. There is a need for a clear statement of what Evidence-Based Practice (EBP means, a description of the skills required to practise in an evidence-based manner and a curriculum that outlines the minimum requirements for training health professionals in EBP. This consensus statement is based on current literature and incorporating the experience of delegates attending the 2003 Conference of Evidence-Based Health Care Teachers and Developers ("Signposting the future of EBHC". Discussion Evidence-Based Practice has evolved in both scope and definition. Evidence-Based Practice (EBP requires that decisions about health care are based on the best available, current, valid and relevant evidence. These decisions should be made by those receiving care, informed by the tacit and explicit knowledge of those providing care, within the context of available resources. Health care professionals must be able to gain, assess, apply and integrate new knowledge and have the ability to adapt to changing circumstances throughout their professional life. Curricula to deliver these aptitudes need to be grounded in the five-step model of EBP, and informed by ongoing research. Core assessment tools for each of the steps should continue to be developed, validated, and made freely available. Summary All health care professionals need to understand the principles of EBP, recognise EBP in action, implement evidence-based policies, and have a critical attitude to their own practice and to evidence. Without these skills, professionals and organisations will find it difficult to provide 'best practice'.

  6. 31 CFR 391.4 - Documentary evidence.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Documentary evidence. 391.4 Section 391.4 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE... § 391.4 Documentary evidence. (a) When late charges are waived, the debtor's administrative file...

  7. The power of Bayesian evidence in astronomy

    CERN Document Server

    Jenkins, C R

    2011-01-01

    We discuss the use of the Bayesian evidence ratio, or Bayes factor, for model selection in astronomy. We treat the evidence ratio as a statistic and investigate its distribution over an ensemble of experiments, considering both simple analytical examples and some more realistic cases, which require numerical simulation. We find that the evidence ratio is a noisy statistic, and thus it may not be sensible to decide to accept or reject a model based solely on whether the evidence ratio reaches some threshold value. The odds suggested by the evidence ratio bear no obvious relationship to the power or Type I error rate of a test based on the evidence ratio. The general performance of such tests is strongly affected by the signal to noise ratio in the data, the assumed priors, and the threshold in the evidence ratio that is taken as `decisive'. The comprehensiveness of the model suite under consideration is also very important. The usefulness of the evidence ratio approach in a given problem can be assessed in adv...

  8. 45 CFR 99.25 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Evidence. 99.25 Section 99.25 Public Welfare... DEVELOPMENT FUND Hearing Procedures § 99.25 Evidence. (a) Testimony. Testimony shall be given orally under... conference or otherwise prior to the hearing if the presiding officer so requires. (c) Rules of...

  9. 14 CFR 16.223 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... party other than the agency except as provided in Department of Transportation regulations at 49 CFR... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Evidence. 16.223 Section 16.223 Aeronautics... PRACTICE FOR FEDERALLY-ASSISTED AIRPORT ENFORCEMENT PROCEEDINGS Hearings § 16.223 Evidence. (a) General....

  10. 28 CFR 76.30 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... be open to examination by all parties, unless otherwise ordered by the Judge pursuant to 28 CFR 76.27. ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Evidence. 76.30 Section 76.30 Judicial... POSSESSION OF CERTAIN CONTROLLED SUBSTANCES § 76.30 Evidence. (a) The Judge shall determine the...

  11. 12 CFR 908.61 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Evidence. 908.61 Section 908.61 Banks and... PRACTICE AND PROCEDURE IN HEARINGS ON THE RECORD Hearing and Post-hearing Proceedings § 908.61 Evidence. (a) Admissibility. (1) Except as is otherwise set forth in this section, relevant, material and reliable...

  12. 42 CFR 422.678 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Evidence. 422.678 Section 422.678 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM MEDICARE ADVANTAGE PROGRAM Medicare Contract Determinations and Appeals § 422.678 Evidence....

  13. Making Evidence-based Practice Educational.

    Science.gov (United States)

    Elliott, John

    2001-01-01

    Examines David Hargreaves' ideas about the nature of evidence-based practice and the future direction for educational research. States that one major theme is that current discourse about evidence-based teaching is uninformed by an articulate educational theory, therefore excluding thoughtful consideration of implications of such a theory for…

  14. 20 CFR 404.1512 - Evidence.

    Science.gov (United States)

    2010-04-01

    ...' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Determining Disability and Blindness Evidence § 404.1512 Evidence. (a) General. In general, you have to prove... month you were last insured for disability insurance benefits (see § 404.130), (2) the month ending...

  15. Careers in Forensics: Analysis, Evidence, and Law

    Science.gov (United States)

    Torpey, Elka Maria

    2009-01-01

    In legal proceedings, a case is only as strong as its evidence. And whether that evidence is strong depends, in large part, on the work of forensic specialists. The field of forensics is broad and involves many kinds of workers. Some of them are involved in crimesolving. Others, such as forensic social workers or forensic economists, help to…

  16. School Resegregation: A Synthesis of the Evidence

    Science.gov (United States)

    Glenn, William J.

    2012-01-01

    This article examines the evidence that supports and rebuts the claims of school resegregation. By examining both types of evidence and considering them complementary (James 1986; Kelly and Miller 1989), the author gives the reader a deeper understanding of the current trends in school segregation. First, the literature on the topic of school…

  17. Utility-driven evidence for healthy cities

    DEFF Research Database (Denmark)

    de Leeuw, Evelyne; Skovgaard, Thomas

    2005-01-01

    challenges for further development and evidence-oriented evaluations of Healthy Cities. There are problems with (1) the communication of evidence, (2) the tension between the original intention of the Healthy Cities Movement and its current operations, and (3) the complex nature of Healthy Cities...... and the methodological tools currently available....

  18. Evidence-Based Clearinghouses in Social Work

    Science.gov (United States)

    Soydan, Haluk; Mullen, Edward J.; Alexandra, Laine; Rehnman, Jenny; Li, You-Ping

    2010-01-01

    Objectives: The purpose of this article is to describe several evidence-based clearinghouses focused on social work and related intervention outcomes, placing them in the context of how such clearinghouses can contribute to research dissemination to foster effective, evidence-based practice. Method: The study employed an analysis of data provided…

  19. 42 CFR 3.540 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... unfair prejudice, confusion of the issues, or by considerations of undue delay or needless presentation... provided in Rule 408 of the Federal Rules of Evidence. (g) Evidence of crimes, wrongs, or acts other than... whether the crimes, wrongs, or acts occurred during the statute of limitations period applicable to...

  20. 34 CFR 33.34 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Evidence. 33.34 Section 33.34 Education Office of the Secretary, Department of Education PROGRAM FRAUD CIVIL REMEDIES ACT § 33.34 Evidence. (a) The ALJ shall... danger of unfair prejudice, confusion of the issues, or by considerations of undue delay or...

  1. 45 CFR 150.445 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... outweighed by the danger of unfair prejudice, confusion of the issues, or by considerations of undue delay or... will be inadmissible to the extent provided in the Federal Rules of Evidence. (g) Evidence of acts... penalty if those acts are used under §§ 150.317 and 150.323 of this part to consider the entity's...

  2. 29 CFR 22.34 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Evidence. 22.34 Section 22.34 Labor Office of the Secretary of Labor PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 22.34 Evidence. (a) The ALJ shall determine the... unfair prejudice, confusion of the issues, or by considerations of undue delay or needless...

  3. 20 CFR 498.217 - Evidence.

    Science.gov (United States)

    2010-04-01

    ... value is substantially outweighed by the danger of unfair prejudice, confusion of the issues, or by... extent provided in Rule 408 of the Federal Rules of Evidence. (f)(1) Evidence of crimes, wrongs or acts... regardless of whether the crimes, wrongs or acts occurred during the statute of limitations period...

  4. 45 CFR 160.540 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... unfair prejudice, confusion of the issues, or by considerations of undue delay or needless presentation... provided in Rule 408 of the Federal Rules of Evidence. (g) Evidence of crimes, wrongs, or acts other than... whether the crimes, wrongs, or acts occurred during the statute of limitations period applicable to...

  5. 8 CFR 1244.9 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... document is unavailable, an affidavit or other credible evidence may be submitted. (1) Evidence of identity... proof of unsuccessful efforts to obtain such identity documents, explaining why the consular process is... identification; and/or (iii) Any national identity document from the alien's country of origin bearing photo...

  6. Implementing Evidence-Based Social Work Practice

    Science.gov (United States)

    Mullen, Edward J.; Bledsoe, Sarah E.; Bellamy, Jennifer L.

    2008-01-01

    Recently, social work has been influenced by new forms of practice that hold promise for bringing practice and research together to strengthen the scientific knowledge base supporting social work intervention. The most recent new practice framework is evidence-based practice. However, although evidence-based practice has many qualities that might…

  7. 44 CFR 68.9 - Admissible evidence.

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Admissible evidence. 68.9 Section 68.9 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF... admissible. (b) Documentary and oral evidence shall be admissible. (c) Admissibility of non-expert...

  8. Advancing Evidence in Preterm Neonatal Medicine

    Science.gov (United States)

    Donahue, Pamela K.; Robinson, Karen A.

    2010-01-01

    Few interventions and treatments for premature infants have undergone the rigors of a randomized controlled trial (RCT), the cornerstone of evidence-based healthcare. Multiple barriers in establishing a quality evidence base for the care of preterm infants are examined including the systematic exclusion of children from drug trials, vulnerability…

  9. [Looking for evidence-based medical informatics].

    Science.gov (United States)

    Coiera, Enrico

    2016-03-01

    e-Health is experiencing a difficult time. On the one side, the forecast is for a bright digital health future created by precision medicine and smart devices. On the other hand, most large scale e-health projects struggle to make a difference and are often controversial. Both futures fail because they are not evidence-based. Medical informatics should follow the example of evidence-based medicine, i.e. conduct rigorous research that gives us evidence to solve real world problems, synthesise that evidence and then apply it strictly. We already have the tools for creating a different universe. What we need is evidence, will, a culture of learning, and hard work. PMID:27030221

  10. Evidence for Mental Health Occupational Therapy

    Directory of Open Access Journals (Sweden)

    Danielle Hitch

    2015-09-01

    Full Text Available This article reports on the evidence for mental health occupational therapy in peer-reviewed journals from 2000 to 2013. Descriptive and inductive methods were used to address this question, with evidence from CINAHL, OTDBase, PSYCInfo, SCOPUS, and Google Scholar® included. Many articles (n = 1,747 were found that met the inclusion and exclusion criteria. A total of 47 different methods were used to develop evidence for mental health occupational therapy, and evidence appeared in 300 separate peer-reviewed journals. It takes on average 7 months for an article to progress from submission to acceptance, and a further 7 months to progress from acceptance to publication. More than 95% of articles published between 2000 and 2002 were cited at least once in the following decade, and around 70% of these citations were recorded in non-occupational therapy journals. The current evidence base for mental health occupational therapy is both substantial and diverse.

  11. Semantic Modelling of Digital Forensic Evidence

    Science.gov (United States)

    Kahvedžić, Damir; Kechadi, Tahar

    The reporting of digital investigation results are traditionally carried out in prose and in a large investigation may require successive communication of findings between different parties. Popular forensic suites aid in the reporting process by storing provenance and positional data but do not automatically encode why the evidence is considered important. In this paper we introduce an evidence management methodology to encode the semantic information of evidence. A structured vocabulary of terms, ontology, is used to model the results in a logical and predefined manner. The descriptions are application independent and automatically organised. The encoded descriptions aim to help the investigation in the task of report writing and evidence communication and can be used in addition to existing evidence management techniques.

  12. Association Between Cannabis and Psychosis: Epidemiologic Evidence.

    Science.gov (United States)

    Gage, Suzanne H; Hickman, Matthew; Zammit, Stanley

    2016-04-01

    Associations between cannabis use and psychotic outcomes are consistently reported, but establishing causality from observational designs can be problematic. We review the evidence from longitudinal studies that have examined this relationship and discuss the epidemiologic evidence for and against interpreting the findings as causal. We also review the evidence identifying groups at particularly high risk of developing psychosis from using cannabis. Overall, evidence from epidemiologic studies provides strong enough evidence to warrant a public health message that cannabis use can increase the risk of psychotic disorders. However, further studies are required to determine the magnitude of this effect, to determine the effect of different strains of cannabis on risk, and to identify high-risk groups particularly susceptible to the effects of cannabis on psychosis. We also discuss complementary epidemiologic methods that can help address these questions.

  13. Comparative standards of evidence in social work.

    Science.gov (United States)

    Ruth, Terrance; Matusitz, Jonathan

    2013-01-01

    In this article the authors analyze relevant and reliable evidence on the effects of the preferable treatment customized to each social work client. In doing so, the authors look at four major standards of evidence: (1) evidence-based practice, (2) collaboration models (i.e., the Cochrane Collaboration and the Campbell Collaboration), (3) knowledge translation, and (4) the Social Work Article Club. The ultimate goal of these standards of evidence is to successfully transfer research into practice. Currently, there is a gap between research and practice as a result of a lack of collaboration. Most social workers do not possess the skills to implement change in practice based on research evidence. The authors' objective is to increase understanding by instilling, in part, positive feelings toward research. PMID:23879353

  14. Ethics, equality and evidence in health promotion

    DEFF Research Database (Denmark)

    Vallgårda, Signild

    2014-01-01

    indicating how this could be done. Conclusions: Including reduction of health inequalities and evidence-informed and ethically defendable interventions in health promotion is a challenge, which is not yet fully met by the National Board of Health. When judged from liberal ethical principles, only few......Abstract Aim: The Danish National Board of Health has expressed its commitment to social equality in health, evidence-informed health promotion and public health ethics, and has issued guidelines for municipalities on health promotion, in Danish named prevention packages.The aim of this article...... is to analyse whether the Board of Health adheres to ideals of equality, evidence and ethics in these guidelines. Methods: An analysis to detect statements about equity, evidence and ethics in 10 health promotion packages directed at municipalities with the aim of guiding the municipalities towards evidence...

  15. Evidence-Based Practice: On the Function of Evidence in Practical Reasoning

    Directory of Open Access Journals (Sweden)

    Tone Kvernbekk

    2014-01-01

    Full Text Available There is a vast literature on evidence-based practice (EBP in education. What function does evidence have in practical deliberations toward decisions about what to do? Most writers on EBP seem to think of evidence largely as quantitative data, serving as a foundation from which practice could and should be directly derived. In this paper I argue that we are better served by according a different and more indirect function to evidence in practical reasoning. To establish this claim I employ Toulmin’s model of argumentation. On this model the evidence-as-foundation view amounts to evidence as data/grounds. The model also offers a different function for evidence, as backing of the warrant, and I argue in this paper that this is a more adequate understanding of the function of evidence in practical reasoning

  16. The Evidence-Based Manifesto for School Librarians

    Science.gov (United States)

    Todd, Ross

    2008-01-01

    School Library Journal's 2007 Leadership Summit, "Where's the Evidence? Understanding the Impact of School Libraries," focused on the topic of evidence-based practice. Evidence-based school librarianship is a systematic approach that engages research-derived evidence, school librarian-observed evidence, and user-reported evidence in the processes…

  17. 20 CFR 219.23 - Evidence to prove death.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Evidence to prove death. 219.23 Section 219... EVIDENCE REQUIRED FOR PAYMENT Evidence of Age and Death § 219.23 Evidence to prove death. (a) Preferred evidence of death. The best evidence of a person's death is— (1) A certified copy of or extract from...

  18. 'We hold these truths to be self-evident': deconstructing 'evidence-based' medical practice.

    Science.gov (United States)

    Devisch, Ignaas; Murray, Stuart J

    2009-12-01

    Rationale, aims and objectives Evidence-based medicine (EBM) claims to be based on 'evidence', rather than 'intuition'. However, EBM's fundamental distinction between quantitative 'evidence' and qualitative 'intuition' is not self-evident. The meaning of 'evidence' is unclear and no studies of quality exist to demonstrate the superiority of EBM in health care settings. This paper argues that, despite itself, EBM holds out only the illusion of conclusive scientific rigour for clinical decision making, and that EBM ultimately is unable to fulfil its own structural criteria for 'evidence'. Methods Our deconstructive analysis of EBM draws on the work of the French philosopher, Jacques Derrida. Deconstruction works in the name of justice to lay bare, to expose what has been hidden from view. In plain language, we deconstruct EBM's paradigm of 'evidence', the randomized controlled trial (RCT), to demonstrate that there cannot be incontrovertible evidence for EBM as such. We argue that EBM therefore 'auto-deconstructs' its own paradigm, and that medical practitioners, policymakers and patients alike ought to be aware of this failure within EBM itself. Results EBM's strict distinction between admissible evidence (based on RCTs) and other supposedly inadmissible evidence is not itself based on evidence, but rather, on intuition. In other words, according to EBM's own logic, there can be no 'evidentiary' basis for its distinction between admissible and inadmissible evidence. Ultimately, to uphold this fundamental distinction, EBM must seek recourse in (bio)political ideology and an epistemology akin to faith. PMID:20367689

  19. Faculty Training in Evidence-Based Medicine: Improving Evidence Acquisition and Critical Appraisal

    Science.gov (United States)

    Nicholson, Laura J.; Warde, Carole M.; Boker, John R.

    2007-01-01

    Introduction: Evidence-based medicine (EBM) integrates published clinical evidence with patient values and clinical expertise, the output of which is informed medical decision making. Key skills for evidence-based practice include acquisition and appraisal of clinical information. Faculty clinicians often lack expertise in these skills and are…

  20. Where's the evidence? An innovative approach to teaching staff about evidence-based practice.

    Science.gov (United States)

    Phillips, Janice M; Heitschmidt, Mary; Joyce, Mary Beth; Staneva, Ilianna; Zemansky, Peggy; Francisco, Mary Ann; Powell, Barbara; Kennedy, Terri; Kranzer, Susan French

    2006-01-01

    Preparing nurses to incorporate research and evidence-based findings into nursing practice is important to meet the needs of patients and their families in today's healthcare arena. This article highlights the use of a mock trial as an innovative approach to educating staff nurses on evidence-based practice and identifies future implications for educating staff nurses on incorporating evidence into nursing practice.

  1. Measuring Use of Research Evidence: The Structured Interview for Evidence Use

    Science.gov (United States)

    Palinkas, Lawrence A.; Garcia, Antonio R.; Aarons, Gregory A.; Finno-Velasquez, Megan; Holloway, Ian W.; Mackie, Thomas I.; Leslie, Laurel K.; Chamberlain, Patricia

    2016-01-01

    Objectives: This article describes the Standard Interview for Evidence Use (SIEU), a measure to assess the level of engagement in acquiring, evaluating, and applying research evidence in health and social service settings. Method: Three scales measuring input, process, and output of research evidence and eight subscales were identified using…

  2. Transferring Evidence into Practice: What Evidence Summaries of Library and Information Studies Research Tell Practitioners

    Science.gov (United States)

    Kloda, Lorie A.; Koufogiannakis, Denise; Mallan, Katrine

    2011-01-01

    Introduction: Critical appraisal is a crucial aspect of evidence-based practice. In order to determine whether research is valid, reliable and applicable, the evidence-based practice process advocates that published research be critically appraised. Between 2006 and 2008, the journal Evidence Based Library and Information Practice published 101…

  3. Evidence-Based Dentistry: What's New?

    Directory of Open Access Journals (Sweden)

    A. Ballini, S. Capodiferro, M. Toia, S. Cantore, G. Favia, G. De Frenza, F.R. Grassi

    2007-01-01

    Full Text Available The importance of evidence for every branch of medicine in teaching in order to orient the practitioners among the great amount of most actual scientific information's, and to support clinical decisions, is well established in health care, including dentistry. The practice of evidence-based medicine is a process of lifelong, self-directed, problem-based learning which leads to the need for clinically important information about diagnosis, prognosis, therapy and other clinical and health care issues. Nowadays the practice of dentistry is becoming more complex and challenging because of the continually changing in dental materials and equipments, an increasingly litigious society, an increase in the emphasis of continuing professional development, the information explosion and the consumer movement associated with advances on the Internet. The need for reliable information and the electronic revolution have come together to allow the “paradigm shift” towards evidence-based health care. Recent years have seen an increase in the importance of evidence-based dentistry, aiming to reduce to the maximum the gap between clinical research and real world dental practice. Aim of evidence-based practice is the systematic literature review, which synthesizes the best evidences and provides the basis for clinical practice guidelines. These practice guidelines give a brief review of what evidence-based dentistry is and how to use it.

  4. Weight of Evidence Allocates Mineral Depositional Zones

    Directory of Open Access Journals (Sweden)

    Abdullah A. Bokhari

    2010-01-01

    Full Text Available Problem statement: Yunnan province in general and Pulang area in particular is geological rich area which prevents field study in multi locations due to high risk outcrop. Approach: New technology such as Geographic Information System (GIS and an ArcView extension module Arcweight of evidence (WofE became very handy to provide safety for researchers and allow organization to control their budget. Results: In order to guide mineral exploration, to achieve the purpose of rapid evaluation of mineral resources a serial of modeled prediction methods were established. Weight of evidence model is to predict the existent thing by combining the known evidence of the study area, the importance of evidence is determined based on statistical method. Contrary to the fuzzy logic method, it avoids the subjective selection of evidence and the subjective evaluation of evidence. The weight of evidence can determine the weight in the same standard conditions (using known mine sites as guidance data, so that the variables can be compared in the united scale, a higher reliability. Conclusion/Recommendations: Comparing predicted and known distribution patterns of porphyry, most mine sites are located in the areas with high posterior probability, forecast area accounts for 11.5% of the entire study area. Predicted results show clearly that the boundary of potential areas and the non-potential areas is clear. Therefore, fuzzy logic and other methods should be applied to predict the results for further comparison. More accurate prediction would draw a big smile on faces of share holders.

  5. Evidence that patients can understand and use?

    Science.gov (United States)

    Santesso, Nancy; Glenton, Claire; Lang, Britta

    2008-01-01

    The impact that research evidence can have on patients making decisions about their own care is often overlooked. Regardless of whether patients want to lead or fully participate in their care, it appears that patients still want to be informed. We have health information that patients could benefit from knowing, a growing body of evidence and experiences about how to translate this information to patients. The Cochrane Collaboration, an organisation that produces and disseminates systematic reviews of healthcare interventions, translates the evidence from their reviews into summaries for the public. Research is presently being conducted to test a format for the plain language summaries. Principles such as presenting evidence in standard qualitative statements, as relative and absolute risks, as natural frequencies, and in tables are being incorporated into the format. Groups within the Collaboration are also translating the evidence for use by patients and the public. Effective strategies are being used to target patients directly and via their physicians, such as dissemination on specific patient group websites and decision aids. Research evidence and experiences can feed into the creation of evidence that patients can understand and use. PMID:19216198

  6. New weighting factors assignment of evidence theory based on evidence distance

    Institute of Scientific and Technical Information of China (English)

    Chen Liangzhou; Shi Wenkang; Du Feng

    2005-01-01

    Evidence theory has been widely used in the information fusion for its effectiveness of the uncertainty reasoning. However, the classical DS evidence theory involves counter-intuitive behaviors when the high conflict information exists. Based on the analysis of some modified methods, Assigning the weighting factors according to the intrinsic characteristics of the existing evidence sources is proposed, which is determined on the evidence distance theory. From the numerical examples, the proposed method provides a reasonable result with good convergence efficiency. In addition, the new rule retrieves to the Yager's formula when all the evidence sources contradict to each other completely.

  7. New solar flare evidence may solve mystery

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    An international group of scientists led by the Mullard Space Science Laboratory (MSSL), University College London, has discovered important new evidence that points to the cataclysmic events that trigger a solar flare and the mechanisms that drive its subsequent evolution.

  8. More Evidence Linking Obesity to Liver Cancer

    Science.gov (United States)

    ... fullstory_161494.html More Evidence Linking Obesity to Liver Cancer And type 2 diabetes more than doubles the ... type 2 diabetes, may raise your risk for liver cancer, a new study suggests. "We found that each ...

  9. Double swab technique for collecting touched evidence.

    Science.gov (United States)

    Pang, B C M; Cheung, B K K

    2007-07-01

    Touched evidence is often submitted to forensic laboratories for DNA analysis. Classical stain recovery technique, involving one wet cotton swab, is commonly used for recovering the touched evidence. Double swab technique, using a wet cotton swab followed by a dry cotton swab, was compared with the classical technique for recovering the touched evidence. The wet cotton swabs and the dry cotton swabs were individually extracted. DNA extracts were quantified and amplified at 15 polymorphic loci. DNA recovered in some of the second dry swabs contained sufficient amount of DNA to yield a DNA profile. This study shows that the double swab technique improves the quality of the resulting DNA profiles. The double swab technique for recovering touched evidence at crime scenes is recommended.

  10. Expert Evidence and International Criminal Justice

    DEFF Research Database (Denmark)

    Appazov, Artur

    The book is a comprehensive narration of the use of expertise in international criminal trials offering reflection on standards concerning the quality and presentation of expert evidence. It analyzes and critiques the rules governing expert evidence in international criminal trials...... the extent to which particularized evidentiary rules for expert evidence in international criminal trials is wanting. Based on comparative analyses of relevant national practices, the book proposes procedural improvements to address some of the challenges associated with the use of expertise in international...... and the strategies employed by counsel and courts relying upon expert evidence and challenges that courts face determining its reliability. In particular, the author considers how the procedural and evidentiary architecture of international criminal courts and tribunals influences the courts' ability to meaningfully...

  11. 28 CFR 68.40 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... excluded because it is not the best evidence, unless its authenticity is challenged, in which case reasonable time shall be given to establish its authenticity. When only portions of a document are to...

  12. De Bijziendheid van evidence based practice

    NARCIS (Netherlands)

    Steyaert, Jan; Biggelaar, Tineke van den; Peels, Johan

    2010-01-01

    Evidence based practice is tegenwoordig "hot"in de sociale sector maar is dat terecht? Is er veel heil van te verwachten en draagt dit bij aan beroepsinnovatie? Kritische beschouwing over een trendy fenomeen.

  13. 16 CFR 3.43 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... danger of unfair prejudice, confusion of the issues, or if the evidence would be misleading, or based on... person, in a manner complying with any Act of Congress or rule prescribed by the Supreme Court...

  14. 31 CFR 16.34 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... FRAUD CIVIL REMEDIES ACT OF 1986 § 16.34 Evidence. (a) The ALJ shall determine the admissibility of... prejudice, confusion of the issues, or by considerations of undue delay or needless presentation...

  15. 7 CFR 1.332 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... Under the Program Fraud Civil Remedies Act of 1986 § 1.332 Evidence. (a) The ALJ shall determine the... danger of unfair prejudice, confusion of the issues, or by considerations of undue delay or...

  16. 38 CFR 42.34 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... IMPLEMENTING THE PROGRAM FRAUD CIVIL REMEDIES ACT § 42.34 Evidence. (a) The ALJ shall determine the... unfair prejudice, confusion of the issues, or by considerations of undue delay or needless...

  17. 20 CFR 355.34 - Evidence.

    Science.gov (United States)

    2010-04-01

    ... UNDER THE PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 355.34 Evidence. (a) The ALJ shall determine the... prejudice, confusion of the issues, or by considerations of undue delay or needless presentation...

  18. 14 CFR 1264.133 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... PENALTIES ACT OF 1986 § 1264.133 Evidence. (a) The presiding officer shall determine the admissibility of... outweighed by the danger of unfair prejudice, confusion of the issues, or by considerations of undue delay...

  19. 41 CFR 105-70.034 - Evidence.

    Science.gov (United States)

    2010-07-01

    ...-IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 105-70.034 Evidence. (a) The ALJ shall determine... danger of unfair prejudice, confusion of the issues, or by considerations of undue delay or...

  20. 28 CFR 71.34 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... REMEDIES ACT OF 1986 Implementation for Actions Initiated by the Department of Justice § 71.34 Evidence. (a... outweighed by the danger of unfair prejudice, confusion of the issues, or by considerations of undue delay...

  1. Limited Evidence for Robot-assisted Surgery

    DEFF Research Database (Denmark)

    Broholm, Malene; Onsberg Hansen, Iben; Rosenberg, Jacob

    2016-01-01

    PURPOSE: To evaluate available evidence on robot-assisted surgery compared with open and laparoscopic surgery. METHOD: The databases Medline, Embase, and Cochrane Library were systematically searched for randomized controlled trials comparing robot-assisted surgery with open and laparoscopic...

  2. Evidence-based equine dentistry: preventive medicine.

    Science.gov (United States)

    Carmalt, James L

    2007-08-01

    Dental problems are some of the most common reasons for a horse to be presented to an equine veterinarian. Despite the importance of anecdotal evidence as a starting point, the science of equine dentistry (especially prophylactic dentistry) has remained poorly supported by evidence-based approaches to diagnosis and treatment. In the 21st century, veterinarians have an ethical responsibility to promote and use the results of evidence-based research and not propagate statements attesting to the purported benefits of intervention without supporting research. Consider also that society is becoming more litigious and therefore is basing treatment plans and advice on published research, which protects the profession from legal challenges concerning our professional conduct. This article reviews the current published evidence concerning the role of equine dentistry in feed digestibility and performance. PMID:17616326

  3. 29 CFR 1603.214 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF THE GOVERNMENT EMPLOYEE RIGHTS ACT OF 1991 Hearings § 1603.214 Evidence. The administrative law judge...

  4. Evidence for multiple photosystems in jellyfish

    DEFF Research Database (Denmark)

    Garm, Anders Lydik; Ekström, Peter

    2010-01-01

    cnidarians even possess multiple photosystems. The evidence is strongest within Cubomedusae where all known species posses 24 eyes of four morphological types. Physiological experiments show that each cubomedusan eye type likely constitutes a separate photosystem controlling separate visually guided...... behaviors. Further, the visual system of cubomedusae also includes extraocular photoreception. The evidence is supported by immunocytochemical and molecular data indicating multiple photopigments in cubomedusae as well as in other cnidarians. Taken together, available data suggest that multiple photosystems...

  5. What determines microenterprise growth? : evidence from Tanzania

    OpenAIRE

    Matlary, Francis Haaland

    2012-01-01

    This study provides empirical evidence on the growth determinants of microenterprises funded by microfinance loans through the analysis of survey data of Tanzanian microentrepreneurs. We find strongly positive correlations between business loans and sales growth; however several factors prevent entrepreneurs from growing their businesses. Evidence of a gender divide and a business formality divide is found, with female entrepreneurs experiencing lower sales growth than their male counterparts...

  6. On data transformations and evidence of nonlinearity

    OpenAIRE

    Bruin, Paul; Franses, Philip Hans

    1998-01-01

    textabstractIn this paper we examine the interaction between data transformation and the empirical evidence obtained when testing for (non-)linearity. For this purpose we examine nonlinear features in 64 monthly and 53 quarterly US macroeconomic variables for a range of Box-Cox data transformations. Our general finding is that evidence of nonlinearity is not independent of the data transformation. Results of simulation experiments substantiate this finding.

  7. History and evidence regarding hydrostatic shock

    OpenAIRE

    Courtney, Michael; Courtney, Amy

    2011-01-01

    This paper reviews the history and evidence related to remote wounding effects of ballistic pressure waves imparted to tissue by the impact of a bullet. Such remote effects are often referred to as hydraulic or hydrostatic shock. In spite of considerable published evidence and a long history, some medical professionals continue to regard the ability of a bullet to injure tissue that is not directly crushed or stretched as mythical (Jandial R, Reichwage B, Levy M, Duenas V, Sturdivan L. Ballis...

  8. Price Rigidity: Microeconomic Evidence and Macroeconomic Implications

    OpenAIRE

    Emi Nakamura; Jón Steinsson

    2013-01-01

    We review recent evidence on price rigidity from the macroeconomics literature and discuss how this evidence is used to inform macroeconomic modeling. Sluggish price adjustment is a leading explanation for the large effects of demand shocks on output and, in particular, the effects of monetary policy on output. A recent influx of data on individual prices has greatly deepened macroeconomists’ understanding of individual price dynamics. However, the analysis of these new data raises a host of ...

  9. Ramadan fasting: Do we need more evidence?

    OpenAIRE

    Mohsen Nematy; Mohsen Mazidi; Peyman Rezaie; Maryam Kazemi; Abdolreza Norouzy; Seyed Amir Reza Mohajeri; Amirreza Razavi

    2015-01-01

    Over a billion of Muslims fast worldwide during Ramadan each year. Through this religious custom, fasting contributes to their health as well as their spiritual growth. However, available evidence regarding the health-benefits of Ramadan fasting is scarce and highly contentious. Although Islam exempts patients from fasting, many fast conceivably, and their clinical condition is prone to deteriorate due to persistent gap between current expert knowledge and conclusive strong evidence regarding...

  10. Inequality, income and poverty: comparative global evidence

    OpenAIRE

    Fosu, Augustin Kwasi

    2010-01-01

    Analysing a large sample of 1980-2004 unbalanced panel data, the current study presents comparative global evidence on the role of (income) inequality in poverty reduction. The evidence involves both an indirect channel via the tendency of high inequality to decrease the rate at which income is transformed to poverty reduction, and the tendency of rising inequality to increase poverty. Based on the basic-needs approach, an analysis-of-covariance model is estimated, with the headcount measure ...

  11. Introducing AORN's new model for evidence rating.

    Science.gov (United States)

    Spruce, Lisa; Van Wicklin, Sharon A; Hicks, Rodney W; Conner, Ramona; Dunn, Debra

    2014-02-01

    Nurses today are expected to implement evidence-based practices in the perioperative setting to assess and implement practice changes. All evidence-based practice begins with a question, a practice problem to address, or a needed change that is identified. To assess the question, a literature search is performed and relevant literature is identified and appraised. The types of evidence used to inform practice can be scientific research (eg, randomized controlled trials, systematic reviews) or nonresearch evidence (eg, regulatory and accrediting agency requirements, professional association practice standards and guidelines, quality improvement project reports). The AORN recommended practices are a synthesis of related knowledge on a given topic, and the authorship process begins with a systematic review of the literature conducted in collaboration with a medical librarian. At least two appraisers independently evaluate the applicable literature for quality and strength by using the AORN Research Appraisal Tool and AORN Non-Research Appraisal Tool. To collectively appraise the evidence supporting particular practice recommendations, the AORN recommended practices authors have implemented a new evidence rating model that is appropriate for research and nonresearch literature and that is relevant to the perioperative setting. PMID:24472588

  12. What is an evidence map? A systematic review of published evidence maps and their definitions, methods, and products

    OpenAIRE

    Miake-Lye, Isomi M; Hempel, Susanne; Shanman, Roberta; Shekelle, Paul G

    2016-01-01

    Background The need for systematic methods for reviewing evidence is continuously increasing. Evidence mapping is one emerging method. There are no authoritative recommendations for what constitutes an evidence map or what methods should be used, and anecdotal evidence suggests heterogeneity in both. Our objectives are to identify published evidence maps and to compare and contrast the presented definitions of evidence mapping, the domains used to classify data in evidence maps, and the form ...

  13. Teaching evidence based medicine in family medicine

    Directory of Open Access Journals (Sweden)

    Davorka Vrdoljak

    2012-05-01

    Full Text Available The concept of evidence based medicine (EBM as the integrationof clinical expertise, patient values and the best evidence was introduced by David Sackett in the 1980’s. Scientific literature in medicine is often marked by expansion, acummulation and quick expiration. Reading all important articles to keep in touch with relevant information is impossible. Finding the best evidence that answers a clinical question in general practice (GP in a short time is not easy. Five useful steps are described –represented by the acronym “5A+E”: assess, ask, acquire, appraise, apply and evaluate.The habit of conducting an evidence search “on the spot’’ is proposed. Although students of medicine at University of Split School of Medicine are taught EBM from the first day of their study and in all courses, their experience of evidence-searching and critical appraisal of the evidence, in real time with real patient is inadequate. Teaching the final-year students the practical use of EBM in a GP’s office is different and can have an important role in their professional development. It can positively impact on quality of their future work in family practice (or some other medical specialty by acquiring this habit of constant evidence-checking to ensure that best practice becomes a mechanism for life-long learning. Conclusion. EBM is a foundation stone of every branch of medicine and important part of Family Medicine as scientific and professional discipline. To have an EB answer resulting from GP’s everyday work is becoming a part of everyday practice.

  14. Medicina embasada em evidências

    Directory of Open Access Journals (Sweden)

    Duncan B.B.

    1999-01-01

    Full Text Available O aumento crescente das opções diagnósticas e terapêuticas cria a necessidade de avaliar sua efetividade, o que pode ser feito, por exemplo, com o ensaio clínico randomizado. A difusão deste e de outros métodos da epidemiologia clínica na prática médica propicia o paradigma da "medicina embasada em evidências". Ao enfatizar a necessidade de evidências clínico-epidemiológicas sólidas para as decisões clínicas, a medicina embasada em evidências forma a estrutura para a integração dos resultados de pesquisas na prática clínica. A evidência é graduada pelo delineamento de pesquisa, fornecendo normas que estabelecem qual o grau adequado para a tomada de decisão médica. A combinação desse novo paradigma com o poder das telecomunicações modernas está causando uma revolução no modo em que a medicina é praticada. O processo é facilitado pelo acesso dos clínicos às revisões quantitativas e aos guidelines (posicionamentos clínicos delas derivados. As limitações das fontes tradicionais de evidências médicas e as vantagens das novas fontes de evidências, como o ACP Journal Club e a Cochrane Collaboration, são descritas. É importante que o médico se familiarize com os conceitos e técnicas do paradigma de medicina embasada em evidências.

  15. 29 CFR 18.401 - Definition of relevant evidence.

    Science.gov (United States)

    2010-07-01

    ... OFFICE OF ADMINISTRATIVE LAW JUDGES Rules of Evidence Relevancy and Its Limits § 18.401 Definition of relevant evidence. Relevant evidence means evidence having any tendency to make the existence of any fact... 29 Labor 1 2010-07-01 2010-07-01 true Definition of relevant evidence. 18.401 Section 18.401...

  16. 20 CFR 404.728 - Evidence a marriage has ended.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Evidence a marriage has ended. 404.728... DISABILITY INSURANCE (1950- ) Evidence Evidence of Age, Marriage, and Death § 404.728 Evidence a marriage has ended. (a) When evidence is needed that a marriage has ended. If you apply for benefits as the...

  17. 20 CFR 404.720 - Evidence of a person's death.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Evidence of a person's death. 404.720 Section... INSURANCE (1950- ) Evidence Evidence of Age, Marriage, and Death § 404.720 Evidence of a person's death. (a) When evidence of death is required. If you apply for benefits on the record of a deceased person,...

  18. 20 CFR 219.24 - Evidence of presumed death.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Evidence of presumed death. 219.24 Section... EVIDENCE REQUIRED FOR PAYMENT Evidence of Age and Death § 219.24 Evidence of presumed death. When a person cannot be proven dead but evidence of death is needed, the Board may presume he or she died at a...

  19. Limitations of Observational Evidence: Implications for Evidence-Based Dietary Recommendations12

    OpenAIRE

    Maki, Kevin C; Slavin, Joanne L; Rains, Tia M.; Kris-Etherton, Penny M

    2014-01-01

    Data from randomized controlled trials (RCTs) provide the strongest evidence for establishing relations between exposures, including dietary exposures, and health outcomes. However, not all diet and health outcome relations can be practically or ethically evaluated by using RCTs; therefore, many dietary recommendations are supported by evidence primarily from observational data, particularly those from prospective cohort studies. Although such evidence is of critical importance, limitations a...

  20. THE EXCLUSION OF ILEGALLY ADMINISTERED EVIDENCE

    Directory of Open Access Journals (Sweden)

    Eliza Emanuela IONIŢĂ

    2015-07-01

    Full Text Available Both judicial practice and specialized texts have brought up the problem of what the punishment for breaking the legal provisions in the activity of evidence administration is, if a matter of fact had been presented by means that are not legally specified or if a piece of evidence was administered by means that are legally specified, but with the violation of legal provisions. Romania has adhered to the most important international juridical instruments adopted in the sphere of human rights by the adoption, modification or completion of internal legislation. As such, for the first time in Romanian criminal procedural legislation, a sanction for the exclusion of evidence has been introduced, as a corollary for the principle of legality and of loyalty in administering evidence. The New Criminal Procedure Code provides the sanction of exclusion as well, but this time the legislator didn’t resume his or herself to a mere conceptual regulation of the sanction, providing both a specific invalidation procedure as well as procedural solutions. In the New Criminal Procedure Code it is shown that in the sphere of evidence-showing a set of rules has been introduced that establishes the principle of loyalty in the obtainment of evidence. These rules, that provide the sanction of excluding evidence obtained through illegal or unloyal means, will determined the growth of professionalism in the ranks of the judiciary bodies on the subject of obtaining evidence and, on the other hand, will guarantee the firm upholding of the parties rights to a fair trial. “Truth, like all other good things, may be loved unwisely – may be pursued too keenly – may cost too much…” Lord Justice Sir James Lewis Knight-Bruce ”It is a deeply ingrained value in our democratic system that the ends do not justify the means. In particular, evidence or convictions may, at times, be obtained at too high a price”. – Antonio Lamer Former Chief Justice of the Supreme Court

  1. Evidence, temperature, and the laws of thermodynamics.

    Science.gov (United States)

    Vieland, Veronica J

    2014-01-01

    A primary purpose of statistical analysis in genetics is the measurement of the strength of evidence for or against hypotheses. As with any type of measurement, a properly calibrated measurement scale is necessary if we want to be able to meaningfully compare degrees of evidence across genetic data sets, across different types of genetic studies and/or across distinct experimental modalities. In previous papers in this journal and elsewhere, my colleagues and I have argued that geneticists ought to care about the scale on which statistical evidence is measured, and we have proposed the Kelvin temperature scale as a template for a context-independent measurement scale for statistical evidence. Moreover, we have claimed that, mathematically speaking, evidence and temperature may be one and the same thing. On first blush, this might seem absurd. Temperature is a property of systems following certain laws of nature (in particular, the 1st and 2nd Law of Thermodynamics) involving very physical quantities (e.g., energy) and processes (e.g., mechanical work). But what do the laws of thermodynamics have to do with statistical systems? Here I address that question. PMID:25358903

  2. Ethics and evidence in psychiatric practice.

    Science.gov (United States)

    Gupta, Mona

    2009-01-01

    Many psychiatrists have endorsed the idea of evidence-based psychiatry, the application of the principles of evidence-based medicine (EBM) to psychiatric practice. Proponents of an evidence-based approach to psychiatry hope that if practice is driven by "hard" scientific data, there will be greater potential to help patients. In other words, advocates of evidence-based psychiatry aim to bolster psychiatry's ethical standing through scientific evidence. Can EBM provide this ethical substantiation to psychiatry? This article provides an overview of some of the main ethical issues within psychiatry and examines three interrelated questions: (1) to which ethical values is EBM committed? (2) which ethical theory is reflected in these values? and (3) can these values and theories resolve existing ethical issues in psychiatry? EBM strives for the "greatest good for the greatest number," where good is defined as improved health. This utilitarian orientation cannot, however, address critical areas of moral importance for psychiatry, such as how its practitioners differentiate normal from abnormal, how they determine which forms of suffering should be alleviated through psychiatric means, and when involuntary intervention is ethically justified. The ethical principles implicit in EBM are too limited to serve as an ethical basis for psychiatry. PMID:19395825

  3. Legislating for health: locating the evidence.

    Science.gov (United States)

    Pawson, Ray; Owen, Lesley; Wong, Geoff

    2010-07-01

    This article examines the timorous courtship between public health law and evidence-based policy. Legislation, in the form of direct prescriptions or proscriptions on behaviour, is perhaps the most powerful tool available to the public health policymaker. Increasingly, the same policymakers have striven to ensure that interventions are based soundly on a secure evidence base. The modern mantra is that the policies to follow are the ones that have been demonstrated to work. Legislative interventions, involving trade-offs between public benefit and private interests, present formidable challenges for the evaluator. Systematic reviews of their overall efficacy, the main tool of evidence-based policy, are in their infancy. The article presents a design for such reviews using the example of a forthcoming synthesis on the effectiveness of banning smoking in cars carrying children.

  4. A Corpus for Evidence Based Medicine Summarisation

    Directory of Open Access Journals (Sweden)

    Diego Mollá Aliod

    2012-09-01

    Full Text Available Background Automated text summarisers that find the best clinical evidence reported in collections of medical literature are of potential benefit for the practice of Evidence Based Medicine (EBM. Research and development of text summarisers for EBM, however, is impeded by the lack of corpora to train and test such systems. Aims To produce a corpus for research in EBM summarisation. Method We sourced the “Clinical Inquiries” section of the Journal of Family Practice (JFP and obtained a sizeable sample of questions and evidence based summaries. We further processed the summaries by combining automated techniques, human annotations, and crowdsourcing techniques to identify the PubMed IDs of the references. Results The corpus has 456 questions, 1,396 answer components, 3,036 answer justifications, and 2,908 references. Conclusion The corpus is now available for the research community at http://sourceforge.net/projects/ebmsumcorpus.

  5. Forensic Evidence in Homicide Investigations and Prosecutions.

    Science.gov (United States)

    McEwen, Tom; Regoeczi, Wendy

    2015-09-01

    Even though forensic evidence is collected at virtually every homicide scene, only a few studies have examined its role in investigation and prosecution. This article adds to the literature by providing the results of a study of 294 homicide cases (315 victims) occurring in Cleveland, Ohio, between 2008 and 2011. Through a logistic regression on open versus closed cases, the collection of knives, administration of gunshot residue (GSR) kits, and clothing at the scene were positively and significantly related to case closures, while collection of ballistics evidence and DNA evidence were statistically significant in the opposite direction. With regard to analysis, the clearance rate for cases with probative results (i.e., matches or exclusions) was 63.1% compared to a closure rate of 56.3% for cases without probative results. However, only 23 cases had probative results prior to arrest compared to 128 cases with probative results after arrest.

  6. Book Review: Challenges to Digital Forensic Evidence

    Directory of Open Access Journals (Sweden)

    Gary Kessler

    2008-03-01

    Full Text Available Cohen, F. (2008. Challenges to Digital Forensic Evidence. Livermore, CA: Fred Cohen & Associates. 129 pages, ISBN: 1-878109-41-3, US$39.Reviewed by Gary C. Kessler (gary.kessler@champlain.eduThis book is about evidence gleaned as the result of the digital forensics process and providing expert testimony about that evidence. I am always suspicious when someone self-proclaims themselves as an "expert" although all authors are doing just that, at least by inference. Readers who are familiar with the author, Fred Cohen, or his large body of published works will know that he neither proclaims his expertise quietly nor inaccurately. Indeed, Cohen is an ideal person to weigh in on the topic of suitability and malleability of information acquired from computers and about providing testimony about that information and the process with which it was found.(see PDF for full review

  7. A consumer guide to phonological evidence

    Directory of Open Access Journals (Sweden)

    Marc van Oostendorp

    2013-02-01

    Full Text Available Normal 0 false false false EN-US JA X-NONE Modern phonological theory is confronted with a wealth of new data from many different sources. This paper gives a summary and taxonomy of the kinds of evidence we currently have at our disposal. For each type it briefly discusses how it has been used, and gives some of the advantages and disadvantages. The main distinction made is between ‘existing’ data and ‘invented’ data, even though it is shown that such distinctions should be considered very carefully. I argue that each type of data can have a function in phonological argumentation, but also that each type of data has some very specific problems. The best evidence is converging evidence from different sources. 

  8. Oncology Nursing Is Evidence-Based Care.

    Science.gov (United States)

    Kennedy Sheldon, Lisa; Brown, Carlton G

    2016-06-01

    This issue of the Clinical Journal of Oncology Nursing (CJON) will be the final time that you will see the Evidence-Based Practice (EBP) feature column. Why? Because we have seen oncology nursing evolve in the past 20 years and EBP is everywhere! We use it in our clinics and hospital units, incorporate it into decisions about symptom management, and use evidence to develop survivorship guidelines. We discuss EBP in journal clubs and use applications on mobile devices to find the best interventions for our patients. We have oncology nurses sitting on committees to develop guidelines based on the best evidence and expert opinion. We have come a long way and it is our belief that EBP is included in almost every article in CJON and, therefore, a need no longer exists for an individual column about EBP. 
. PMID:27206287

  9. The fallacy of evidence based policy

    CERN Document Server

    Saltelli, Andrea

    2016-01-01

    The use of science for policy is at the core of a perfect storm generated by the insurgence of several concurrent crises: of science, of trust, of sustainability. The modern positivistic model of science for policy, known as evidence based policy, is based on dramatic simplifications and compressions of available perceptions of the state of affairs and possible explanations (hypocognition). This model can result in flawed prescriptions. The flaws become more evident when dealing with complex issues characterized by concomitant uncertainties in the normative, descriptive and ethical domains. In this situation evidence-based policy may concur to the fragility of the social system. Science plays an important role in reducing the feeling of vulnerability of humans by projecting a promise of protection against uncertainties. In many applications quantitative science is used to remove uncertainty by transforming it into probability, so that mathematical modelling can play the ritual role of haruspices. This epistem...

  10. Forensic Evidence in Homicide Investigations and Prosecutions.

    Science.gov (United States)

    McEwen, Tom; Regoeczi, Wendy

    2015-09-01

    Even though forensic evidence is collected at virtually every homicide scene, only a few studies have examined its role in investigation and prosecution. This article adds to the literature by providing the results of a study of 294 homicide cases (315 victims) occurring in Cleveland, Ohio, between 2008 and 2011. Through a logistic regression on open versus closed cases, the collection of knives, administration of gunshot residue (GSR) kits, and clothing at the scene were positively and significantly related to case closures, while collection of ballistics evidence and DNA evidence were statistically significant in the opposite direction. With regard to analysis, the clearance rate for cases with probative results (i.e., matches or exclusions) was 63.1% compared to a closure rate of 56.3% for cases without probative results. However, only 23 cases had probative results prior to arrest compared to 128 cases with probative results after arrest. PMID:26174557

  11. Evidence-based policymaking: A review

    Directory of Open Access Journals (Sweden)

    Karen Nortje

    2010-05-01

    Full Text Available The process of facilitating the uptake of evidence, for example, scientific research findings, into the policymaking process is multifaceted and thus complex. It is therefore important for scientists to understand this process in order to influence it more effectively. Similarly, policymakers need to understand the complexities of the scientific process to improve their interaction with the scientific sphere. This literature review addresses those factors that influence the uptake of scientific evidence into policymaking, the barriers to using science in policymaking, as well as recommendations for improved science–policymaking interaction. A visual diagram of the gears of a car is used to convey the message of the complexities around the engagement between science and policymaking. It is concluded that the issue of evidence-based policymaking remains unresolved and questions for future research on the science–policy interface are raised.

  12. Evidence-based Management of Glaucoma

    Institute of Scientific and Technical Information of China (English)

    Yangfan Yang; Minbin Yu

    2005-01-01

    Purpose: The evidence-based medicine (EBM) is a new medical mode that is completely different from traditional experience-based medicine. The core of EBM is that decision-making during clinical practices must be based on objective research results.With the rapid development of modern ophthalmology, some former viewpoints according to experience-based medicine face challenges. Evidence-based ophthalmology (EBO) is imperative under the situation. Glaucoma, as a disease resulting in blindness, which can not be cured by operation, is thought more and more of by medical management officials and doctors. One challenge for ophthalmologists entering the 21st century will be to make clinical decisions based on valid information or evidence rather than intuition, hearsay, or peer practice. How can we do? Here reviews the application of EBM in medical management of glaucoma since EBM' s naissance and give a reference.

  13. Evidence of non-canonical NOTCH signaling

    DEFF Research Database (Denmark)

    Traustadóttir, Gunnhildur Ásta; Jensen, Charlotte H; Thomassen, Mads;

    2016-01-01

    suggested to interact with NOTCH1 and act as an antagonist. This non-canonical interaction is, however controversial, and evidence for a direct interaction, still lacking in mammals. In this study, we elucidated the putative DLK1-NOTCH1 interaction in a mammalian context. Taking a global approach and using...... this interaction to occur between EGF domains 5 and 6 of DLK1 and EGF domains 10-15 of NOTCH1. Thus, our data provide the first evidence for a direct interaction between DLK1 and NOTCH1 in mammals, and substantiate that non-canonical NOTCH ligands exist, adding to the complexity of NOTCH signaling....

  14. Best evidence: nasogastric tube placement verification.

    Science.gov (United States)

    Longo, M Anne

    2011-08-01

    Further research on cost-effective techniques to verify enteral tube placement is warranted using a variety of pediatric populations with differing conditions that may impact gastric pH. It is imperative that clinical facilities review current policies and procedures to ensure that evidence-based findings are guiding nursing practice. Many nurses continue to rely on auscultation to verify NGT placement. Education and competency validation can assist with current practices for NGT placement being consistently incorporated by all personnel in the health care setting. Continuing to search for evidence related to nursing care will guide the direct care RN in providing best practice.

  15. Psychology and Economics: Evidence from the Field

    OpenAIRE

    Stefano DellaVigna

    2007-01-01

    The research in Psychology and Economics (a.k.a. Behavioral Economics) suggests that individuals deviate from the standard model in three respects: (i) non-standard preferences; (ii) non-standard beliefs; and (iii) non-standard decision-making. In this paper, I survey the empirical evidence from the field on these three classes of deviations. The evidence covers a number of applications, from consumption to finance, from crime to voting, from giving to labor supply. In the class of non-standa...

  16. Study Questions Reliability of Fingerprint Evidence

    Institute of Scientific and Technical Information of China (English)

    James; Randerson; 陈易

    2007-01-01

    The reliability of fingerprint has been called into question by a study that tested whether forensic experts make consistent judgments on print matches.Despite the perceived infallibility of fingerprint evidence, the study found that experts do not always make the same judgment on whether a print matches a mark at a crime scene when presented with the same evidence twice.The findings come in the wake of two high profile cases in which fingerprint matches were subsequently shown to be wrong. The Scottish ...

  17. Professionalism and evidence-based practice

    DEFF Research Database (Denmark)

    Rasmussen, Palle

    2015-01-01

    The idea of evidence- based practice is influential in public welfare services, including education. The idea is controversial, however, not least because it involves a poten tial redefinition of the relation ship between knowledge, authority and professionalism. This is discussed based on a study...... of evidence- based methods in Danish pre-school education and care. The management sees the use of these methods as strengthening pre- school teacher professionalism, but the actual practices in the day-careinstitutions are ambiguous. In some cases, using the methods becomes an end in itself and tends...

  18. Evidence Based Practice: Science? Or Art? (Editorial

    Directory of Open Access Journals (Sweden)

    Denise Koufogiannakis

    2011-03-01

    Full Text Available Evidence based library and information practice (EBLIP is a strategy to bridge research and practice. Generally EBLIP is seen as a movement to encourage and give practitioners the means to incorporate research into their practice, where it previously may have been lacking. The widely accepted definition of EBLIP (Booth, 2000 stresses three aspects that contribute to a practice that is evidence based: 1 "the best available evidence;" 2 "moderated by user needs and preferences;" 3 "applied to improve the quality of professional judgements." The area that the EBLIP movement has focused on is how to create and understand the best available research evidence. CE courses, critical appraisal checklists, and many articles have been written to address a need for librarian education in this area, and it seems that strides have been made.But very little in the EBLIP literature talks about how we make professional judgements, or moderate evidence based on our user needs and preferences. Likewise, how do we make good evidence based decisions when our evidence base is weak. These things seem to be elements we just take for granted or can’t translate into words. It is in keeping with tacit knowledge that librarians just seem to have or acquire skills with education and on the job experience. Tacit knowledge is "knowledge that is not easily articulated, and frequently involves knowledge of how to do things. We can infer its existence only by observing behaviour and determining that this sort of knowledge is a precondition for effective performance" (Patel, Arocha, & Kaufman, 1999, p.78. It is something that is difficult to translate into an article or guideline for how we work. I think of this area as the "art" of evidence based practice. And the art is crucial to being an evidence based practitioner.Science = systematized knowledge, explicit research, methodological examination, investigation, dataArt = professional knowledge of your craft, intuition

  19. Observation, Sherlock Holmes, and Evidence Based Medicine.

    Science.gov (United States)

    Osborn, John

    2002-01-01

    Sir Arthur Conan Doyle, the creator of the fictional detective Sherlock Holmes, studied medicine at the University of Edinburgh between 1876 and 1881 under Doctor Joseph Bell who emphasised in his teaching the importance of observation, deduction and evidence. Sherlock Holmes was modelled on Joseph Bell. The modern notions of Evidence Based Medicine (EBM) are not new. A very brief indication of some of the history of EBM is presented including a discussion of the important and usually overlooked contribution of statisticians to the Popperian philosophy of EBM.

  20. Observation, Sherlock Holmes, and Evidence Based Medicine.

    Science.gov (United States)

    Osborn, John

    2002-01-01

    Sir Arthur Conan Doyle, the creator of the fictional detective Sherlock Holmes, studied medicine at the University of Edinburgh between 1876 and 1881 under Doctor Joseph Bell who emphasised in his teaching the importance of observation, deduction and evidence. Sherlock Holmes was modelled on Joseph Bell. The modern notions of Evidence Based Medicine (EBM) are not new. A very brief indication of some of the history of EBM is presented including a discussion of the important and usually overlooked contribution of statisticians to the Popperian philosophy of EBM. PMID:14509997

  1. Evidence for collisionless magnetic reconnection at Mars

    Science.gov (United States)

    Eastwood, J. P.; Brain, D. A.; Halekas, J. S.; Drake, J. F.; Phan, T. D.; Øieroset, M.; Mitchell, D. L.; Lin, R. P.; Acuña, M.

    2008-01-01

    Using data from Mars Global Surveyor (MGS) in combination with Particle-In-Cell (PIC) simulations of reconnection, we present the first direct evidence of collisionless magnetic reconnection at Mars. The evidence indicates that the spacecraft passed through the diffusion region where reconnection is initiated and observed the magnetic field signatures of differential electron and ion motion - the Hall magnetic field - that uniquely indicate the reconnection process. These are the first such in-situ reconnection observations at an astronomical body other than the Earth. Reconnection may be the source of Mars' recently discovered auroral activity and the changing boundaries of the closed regions of crustal magnetic field.

  2. Crime prevention: more evidence-based analysis.

    Science.gov (United States)

    Garrido Genovés, Vicente; Farrington, David P; Welsh, Brandon C

    2008-02-01

    This paper introduces a new section of Psicothema dedicated to the evidence-based approach to crime prevention. Along with an original sexual-offender-treatment programme implemented in Spain, this section presents four systematic reviews of important subjects in the criminological arena, such as sexual offender treatment, the well-known programme, the effectiveness of custodial versus non-custodial sanctions in reoffending and the fight against terrorism. We also highlight some of the focal points that scientists, practitioners and governments should take into account in order to support this evidence-based viewpoint of crime prevention.

  3. How evidence-based are the recommendations in evidence-based guidelines?

    Directory of Open Access Journals (Sweden)

    Finlay A McAlister

    2007-08-01

    Full Text Available BACKGROUND: Treatment recommendations for the same condition from different guideline bodies often disagree, even when the same randomized controlled trial (RCT evidence is cited. Guideline appraisal tools focus on methodology and quality of reporting, but not on the nature of the supporting evidence. This study was done to evaluate the quality of the evidence (based on consideration of its internal validity, clinical relevance, and applicability underlying therapy recommendations in evidence-based clinical practice guidelines. METHODS AND FINDINGS: A cross-sectional analysis of cardiovascular risk management recommendations was performed for three different conditions (diabetes mellitus, dyslipidemia, and hypertension from three pan-national guideline panels (from the United States, Canada, and Europe. Of the 338 treatment recommendations in these nine guidelines, 231 (68% cited RCT evidence but only 105 (45% of these RCT-based recommendations were based on high-quality evidence. RCT-based evidence was downgraded most often because of reservations about the applicability of the RCT to the populations specified in the guideline recommendation (64/126 cases, 51% or because the RCT reported surrogate outcomes (59/126 cases, 47%. CONCLUSIONS: The results of internally valid RCTs may not be applicable to the populations, interventions, or outcomes specified in a guideline recommendation and therefore should not always be assumed to provide high-quality evidence for therapy recommendations.

  4. Competency, confidence and conflicting evidence: key issues affecting health visitors' use of research evidence in practice

    Directory of Open Access Journals (Sweden)

    Calnan Michael

    2009-04-01

    Full Text Available Abstract Background Health visitors play a pivotal position in providing parents with up-to-date evidence-based care on child health. The recent controversy over the safety of the MMR vaccine has drawn attention to the difficulties they face when new research which raises doubts about current guidelines and practices is published. In the aftermath of the MMR controversy, this paper investigates the sources health visitors use to find out about new research evidence on immunisation and examines barriers and facilitators to using evidence in practice. It also assesses health visitors' confidence in using research evidence. Methods Health visitors were recruited from the 2007 UK Community Practitioners' and Health Visitors' Association conference. All delegates were eligible to complete the questionnaire if in their current professional role they advise parents about childhood immunisation or administer vaccines to children. Of 228 who were eligible, 185 completed the survey (81.1%. Results These health visitors used a wide range of resources to find out about new research evidence on childhood immunisation. Popular sources included information leaflets and publications, training days, nursing journals and networking with colleagues. A lack of time was cited as the main barrier to searching for new evidence. The most common reason given for not using research in practice was a perception of conflicting research evidence. Understanding the evidence was a key facilitator. Health visitors expressed less confidence about searching and explaining research on childhood immunisation than evidence on weaning and a baby's sleep position. Conclusion Even motivated health visitors feel they lack the time and, in some cases, the skills to locate and appraise research evidence. This research suggests that of the provision of already-appraised research would help to keep busy health professionals informed, up-to-date and confident in responding to public

  5. Employing Evidence Evidence: Does it Have a Job in Vocational Libraries?

    Directory of Open Access Journals (Sweden)

    Brad Jones

    2006-03-01

    Full Text Available Objective - Evidence-based librarianship (EBL springs ffrom medical and academic origins. As librarians are tertiary educated (only occasionally with supplementary qualifications covering research and statistics EBL has an academic focus. The EBL literature has significant content from school and university perspectives, but has had little, if any, vocational content. This paper suggests a possible Evidence Based Librarianship context for vocational libraries. Methods - A multidisciplinary scan of evidence based literature was undertaken, covering medicine and allied health, librarianship, law, science and education. National and international vocational education developments were examined. The concept and use of evidence in vocational libraries was considered. Results - Library practice can generally benefit from generic empirical science methodologies used elsewhere. Different areas, however, may have different concepts of what constitutes evidence and appropriate methodologies. Libraries also need to reflect the evidence used in their host organisations. The Australian vocational librarian has been functioning in an evidence based educational sector: national, transportable, prescriptive, competancy based and outcomes drived Training Packages. These require a qualitatively different concept of evidence compared to the other educational sectors as they reflect pragmatic, economic, employability outcomes. Conclusions - Vocational and other librarians have been doing research but need to be more systematic about design and analysis. Librarians need to develop 'evidence literacy' as one of their professional evaluation skills. Libraries will need to utilise evidence relevant to their host organisations to esablish and maintain credibility, and in the vocational sector this is set in a competency based framework. Competancy based measures are becoming increasingly relevant in school and university(including medical education.

  6. Justifying Physical Education Based on Neuroscience Evidence

    Science.gov (United States)

    Berg, Kris

    2010-01-01

    Research has shown that exercise improves cognitive function and psychological traits that influence behavior (e.g., mood, level of motivation). The evidence in the literature also shows that physical education may enhance learning or that academic performance is at least maintained despite a reduction in classroom time in order to increase time…

  7. Evidence-Based Classroom Behaviour Management Strategies

    Science.gov (United States)

    Parsonson, Barry S.

    2012-01-01

    This paper reviews a range of evidence-based strategies for application by teachers to reduce disruptive and challenging behaviours in their classrooms. These include a number of antecedent strategies intended to help minimise the emergence of problematic behaviours and a range of those which provide positive consequences for appropriate student…

  8. 20 CFR 726.311 - Evidence.

    Science.gov (United States)

    2010-04-01

    ... Administrative Hearings Before the Office of Administrative Law Judges established by the Secretary at 29 CFR part 18 shall apply to administrative proceedings under this subpart. (b) Notwithstanding 29 CFR 18... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Evidence. 726.311 Section 726.311...

  9. 40 CFR 22.22 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... pursuant to 40 CFR part 2. A business confidentiality claim shall not prevent information from being introduced into evidence, but shall instead require that the information be treated in accordance with 40 CFR... necessary. Such proceeding shall be closed only to the extent necessary to comply with 40 CFR part...

  10. Emotional Intelligence and Teaching: Further Validation Evidence

    Science.gov (United States)

    Perry, Chris; Ball, Ian

    2005-01-01

    Further evidence is presented to demonstrate the validity of a new measure of emotional intelligence: Reactions to Teaching Situations (RTS). Using criterion-related groups of high and low scorers on the RTS, it is shown that high scorers give more responses coded as emotional intelligence in their answers to sentence completion tasks relating to…

  11. Managing Records as Evidence and Information.

    Science.gov (United States)

    Cox, Richard J.

    For the past three decades, policies regarding a variety of information issues have emanated from federal agencies, legislative chambers, and corporate boardrooms. Records policies are critically important for records professionals to develop and use as a means of strategically managing the information and evidence found in the millions of records…

  12. Education and Poverty: Confronting the Evidence

    Science.gov (United States)

    Ladd, Helen F.

    2012-01-01

    Current U.S. policy initiatives to improve the U.S. education system, including No Child Left Behind, test-based evaluation of teachers, and the promotion of competition are misguided because they either deny or set to the side a basic body of evidence documenting that students from disadvantaged households on average perform less well in school…

  13. GARCH Option Valuation: Theory and Evidence

    DEFF Research Database (Denmark)

    Christoffersen, Peter; Jacobs, Kris; Ornthanalai, Chayawat

    We survey the theory and empirical evidence on GARCH option valuation models. Our treatment includes the range of functional forms available for the volatility dynamic, multifactor models, nonnormal shock distributions as well as style of pricing kernels typically used. Various strategies...

  14. 40 CFR 164.81 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Evidence. 164.81 Section 164.81 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS RULES OF PRACTICE GOVERNING HEARINGS, UNDER THE FEDERAL INSECTICIDE, FUNGICIDE, AND RODENTICIDE ACT, ARISING FROM REFUSALS...

  15. International Evidence on Sectoral Interfuel Substitution

    OpenAIRE

    Serletis, Apostolos; Timilsina, Govinda R.; Vasetsky, Olexandr

    2010-01-01

    This paper estimates interfuel substitution elasticities in selected developing and industrialized economies at the sector level. In doing so, it employs state-of-the-art techniques in microeconometrics, particularly the locally flexible normalized quadratic functional form, and provides evidence consistent with neoclassical microeconomic theory. The results indicate that the interfuel substitution elasticities are consistently below unity, revealing the limited ability to substitute between ...

  16. On interfuel substitution : some international evidence

    OpenAIRE

    Serletis, Apostolos; Timilsina, Govinda; Vasetsky, Olexandr

    2009-01-01

    This paper estimates interfuel substitution elasticities in selected developing and industrialized economies at the national and sector levels. In doing so, it employs state-of-the-art techniques in microeconometrics, particularly the locally flexible normalized quadratic functional forms, and provides evidence consistent with neoclassical microeconomic theory. The results indicate that th...

  17. An evidence-based view on hyperbilirubinaemia

    NARCIS (Netherlands)

    Dijk, Peter H.; Hulzebos, Christian V.

    2012-01-01

    Introduction: We conducted a review of the evidence which contributes to the current care of jaundiced newborn infants. Methods: Literature was searched for reviews and randomized controlled trials (RCTs). Results: Six Cochrane reviews and eight other reviews and eighteen recent RCTs are discussed.

  18. Evidence for Future Cognition in Animals

    Science.gov (United States)

    Roberts, William A.

    2012-01-01

    Evidence concerning the possibility of mental time travel into the future by animals was reviewed. Both experimental laboratory studies and field observations were considered. Paradigms for the study of future anticipation and planning included inhibition of consumption of current food contingent on future receipt of either a larger quantity or…

  19. Environment and Happiness: New Evidence for Spain

    Science.gov (United States)

    Cunado, Juncal; Perez de Gracia, Fernando

    2013-01-01

    This paper explores the relationship between air pollution, climate and reported subjective well-being (or happiness) in Spanish regions. The results show that, after controlling for most of the socio-economic variables affecting happiness, there are still significant regional differences in subjective well-being. Evidence also suggests that…

  20. Competition and Innovation: Evidence from Financial Services

    NARCIS (Netherlands)

    Bos, J.W.B.; Kolari, J.; van Lamoen, R.

    2009-01-01

    In this paper we seek to contribute to the literature on competition and innovation by focusing on individual firms within the U.S. banking industry in the period 1984-2004. We measure innovation by estimating technology gaps and find evidence of an inverted-U relationship between competition and th

  1. 21 CFR 514.4 - Substantial evidence.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Substantial evidence. 514.4 Section 514.4 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... for use other than in animal feed or drinking water. (iii) Antibacterial with respect to a...

  2. Evidence Scan of Work Experience Programs

    OpenAIRE

    Samina Sattar

    2010-01-01

    This report presents evidence on the effectiveness of interventions that include work experience as a strategy to improve employment outcomes for people with barriers to employment. The report reviews 26 years of rigorous research gathering information from 27 evaluations. The author distinguishes between interventions targeting adults versus youth, paid versus unpaid work, and length of work opportunity.

  3. Evidence for a jacketed nematic polymer

    OpenAIRE

    Hardouin, F.; Mery, S.; Achard, M.; Noirez, L.; Keller, P.

    1991-01-01

    The evidence for a “jacketed” structure at the scale of the chain dimensions in the nematic phase of a “side-on fixed” liquid crystal polysiloxane is reported by using small angle neutron scattering. We relate this anisotropy of chain conformation to the first measurements of the rotational viscosity coefficient in this new type of liquid crystal side-chain polymer.

  4. 20 CFR 410.240 - Evidence.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Evidence. 410.240 Section 410.240 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL COAL MINE HEALTH AND SAFETY ACT OF 1969, TITLE IV-BLACK... claims, including the reasonable and necessary cost of travel incident thereto. A medical...

  5. Social Science Evidence in Court Cases

    Science.gov (United States)

    Doyle, William E.

    1977-01-01

    Can social science data be used in judicial decision-making? Suggests that social science data is less important in judicial decision-making in the field of constitutional law than most persons think and considers the more controversial issue of whether courts should be considering cases which might require or produce social science evidence.…

  6. Evidence Based Complementary Intervention for Insomnia

    OpenAIRE

    Lopez, Dr. Hassen H.; Bracha, Adam S.; Bracha, Dr. Stefan

    2002-01-01

    Increasing scientific evidence point to a non-pharmacological complementary treatment for insomnia: white noise. Its presentation has been shown to induce sleep in human neonates and adults, probably by reducing the signal-to-noise ratio of ambient sound. White noise may be a simple, safe, cost-effective alternative to hypnotic medication in many psychiatric disorders, especially acute stress disorder and PTSD.

  7. DISCOVERY OF EVIDENCE IN INTERNATIONAL COMMERCIAL ARBITRATION

    Directory of Open Access Journals (Sweden)

    Bakumenko, V.V.

    2016-07-01

    Full Text Available The article considers the different concepts of discovery of evidence, which exist under different legal jurisdictions, with their theoretical analysis to determine the feasibility and rationality of the application of the discovery mechanisms in the frameworks of international commercial arbitration and its fundamental principles.

  8. Complex dynamics and empirical evidence (Invited Paper)

    Science.gov (United States)

    Delli Gatti, Domenico; Gaffeo, Edoardo; Giulioni, Gianfranco; Gallegati, Mauro; Kirman, Alan; Palestrini, Antonio; Russo, Alberto

    2005-05-01

    Standard macroeconomics, based on a reductionist approach centered on the representative agent, is badly equipped to explain the empirical evidence where heterogeneity and industrial dynamics are the rule. In this paper we show that a simple agent-based model of heterogeneous financially fragile agents is able to replicate a large number of scaling type stylized facts with a remarkable degree of statistical precision.

  9. On data transformations and evidence of nonlinearity

    NARCIS (Netherlands)

    P. de Bruin (Paul); Ph.H.B.F. Franses (Philip Hans)

    1998-01-01

    textabstractIn this paper we examine the interaction between data transformation and the empirical evidence obtained when testing for (non-)linearity. For this purpose we examine nonlinear features in 64 monthly and 53 quarterly US macroeconomic variables for a range of Box-Cox data transformatio

  10. Improving GRADE evidence tables part 2

    DEFF Research Database (Denmark)

    Langendam, Miranda; Carrasco-Labra, Alonso; Santesso, Nancy;

    2016-01-01

    or control group risk) was often missing. For judgments about downgrading the quality of evidence, the percentage of informative explanations ranged between 41% (imprecision) and 79% (indirectness). CONCLUSION: We found that by and large explanations were informative but detected several areas...

  11. Evidence-based recommendation on toothpaste use

    Directory of Open Access Journals (Sweden)

    Jaime Aparecido Cury

    2014-01-01

    Full Text Available Toothpaste can be used as a vehicle for substances to improve the oral health of individuals and populations. Therefore, it should be recommended based on the best scientific evidence available, and not on the opinion of authorities or specialists. Fluoride is the most important therapeutic substance used in toothpastes, adding to the effect of mechanical toothbrushing on dental caries control. The use of fluoride toothpaste to reduce caries in children and adults is strongly based on evidence, and is dependent on the concentration (minimum of 1000 ppm F and frequency of fluoride toothpaste use (2'/day or higher. The risk of dental fluorosis due to toothpaste ingestion by children has been overestimated, since there is no evidence that: 1 fluoride toothpaste use should be postponed until the age of 3-4 or older, 2 low-fluoride toothpaste avoids fluorosis and 3 fluorosis has a detrimental effect on the quality of life of individuals exposed to fluoridated water and toothpaste. Among other therapeutic substances used in toothpastes, there is evidence that triclosan/copolymer reduce dental biofilm, gingivitis, periodontitis, calculus and halitosis, and that toothpastes containing stannous fluoride reduce biofilm and gingivitis.

  12. Learning From Others About Research Evidence (editorial

    Directory of Open Access Journals (Sweden)

    Alison Brettle

    2012-06-01

    Full Text Available Welcome to the June issue of EBLIP, our firstto be published with an HTML version as wellas PDFs for each article. I hope you enjoy andfind the alternative formats useful. As usualthe issue comprises an interesting range ofevidence summaries and articles that I hopeyou will find useful in applying evidence toyour practice.When considering evidence, two recent trips toEdinburgh got me thinking about the widerange of study designs or methods that areuseful for generating evidence, and also howwe can learn about their use from otherprofessions.The first trip was as part of the cadre of the LISDREaM project (http://lisresearch.org/dreamproject/.DREaM has been set up by the LISResearch Coalition to develop a sustainableLIS research network in the UK. As part ofthis, a series of workshops aims to introduceLIS practitioners to a wider range of researchmethods, thus expanding the methods used inLIS research. Indeed, a quick scan of thecontents of this issue show a preponderance ofsurveys, interviews, and citation analysis,suggesting that broadening our knowledge ofmethods may well be a useful idea. Theworkshops are highly interactive and, at eachsession experts from outside the LIS disciplineintroduce particular research methods andoutline how they could be used in LISapplications. As a result, I can see the valueand understand when to use research methodssuch as social network analysis, horizonscanning, ethnography, discourse analysis, andrepertory grids – as well as knowing that datamining is something I’m likely to avoid! So farI’ve shared my new knowledge with a PhDstudent who was considering her methodologyand incorporated my new knowledge ofhorizon scanning into a bid for researchfunding. The next (and more exciting step isto think of a situation where I can apply one ofthese methods to examining an aspect of LIS practice.The second trip was the British Association ofCounselling and Psychotherapy ResearchConference, an event which I

  13. Income Aspirations and Cooperation : Experimental Evidence

    NARCIS (Netherlands)

    Dalton, P.S.

    2010-01-01

    This article is the first attempt to study the empirical link between income aspirations and cooperation in a one shot public good game. By combining experimental with survey data, we find evidence that the more frustrated people are with their income, the lower is their propensity to cooperate with

  14. 42 CFR 426.440 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Evidence. 426.440 Section 426.440 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM REVIEW OF NATIONAL COVERAGE DETERMINATIONS AND LOCAL COVERAGE DETERMINATIONS Review of an...

  15. 42 CFR 426.540 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Evidence. 426.540 Section 426.540 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM REVIEW OF NATIONAL COVERAGE DETERMINATIONS AND LOCAL COVERAGE DETERMINATIONS Review of an...

  16. Wellness programs: a review of the evidence

    OpenAIRE

    Watt, D.; S Verma; Flynn, L.

    1998-01-01

    OBJECTIVE: To review studies that have examined an association between wellness programs and improvements in quality of life and to assess the strength of the scientific evidence. DATA SOURCES: A MEDLINE search was constructed with the following medical subject headings: "psychoneuroimmunology," "chronic disease" and "health promotion," "chronic disease" and "health behaviour," "relaxation techniques," "music therapy," "laughter," "anger," "mediation" and "behavioural medicine." Searches usin...

  17. Digital Natives: Where Is the Evidence?

    Science.gov (United States)

    Helsper, Ellen Johanna; Eynon, Rebecca

    2010-01-01

    Generational differences are seen as the cause of wide shifts in our ability to engage with technologies and the concept of the digital native has gained popularity in certain areas of policy and practice. This paper provides evidence, through the analysis of a nationally representative survey in the UK, that generation is only one of the…

  18. African American Homeschooling Practices: Empirical Evidence

    Science.gov (United States)

    Mazama, Ama

    2016-01-01

    Despite a significant increase in scholarly interest for homeschooling, some of its most critical aspects, such as instructional daily practices, remain grossly understudied. This essay thus seeks to fill that void by presenting empirical evidence regarding the homeschooling practices of a specific group, African Americans. Most specifically, the…

  19. BELTracker: evidence sentence retrieval for BEL statements.

    Science.gov (United States)

    Rastegar-Mojarad, Majid; Komandur Elayavilli, Ravikumar; Liu, Hongfang

    2016-01-01

    Biological expression language (BEL) is one of the main formal representation models of biological networks. The primary source of information for curating biological networks in BEL representation has been literature. It remains a challenge to identify relevant articles and the corresponding evidence statements for curating and validating BEL statements. In this paper, we describe BELTracker, a tool used to retrieve and rank evidence sentences from PubMed abstracts and full-text articles for a given BEL statement (per the 2015 task requirements of BioCreative V BEL Task). The system is comprised of three main components, (i) translation of a given BEL statement to an information retrieval (IR) query, (ii) retrieval of relevant PubMed citations and (iii) finding and ranking the evidence sentences in those citations. BELTracker uses a combination of multiple approaches based on traditional IR, machine learning, and heuristics to accomplish the task. The system identified and ranked at least one fully relevant evidence sentence in the top 10 retrieved sentences for 72 out of 97 BEL statements in the test set. BELTracker achieved a precision of 0.392, 0.532 and 0.615 when evaluated with three criteria, namely full, relaxed and context criteria, respectively, by the task organizers. Our team at Mayo Clinic was the only participant in this task. BELTracker is available as a RESTful API and is available for public use.Database URL: http://www.openbionlp.org:8080/BelTracker/finder/Given_BEL_Statement. PMID:27173525

  20. Intuitive Expertise: Theories and Empirical Evidence

    Science.gov (United States)

    Harteis, Christian; Billett, Stephen

    2013-01-01

    Intuition has been long seen as an element of effective human performance in demanding tasks (i.e. expertise). But its form, constitutive elements and development remain subject to diverse explanations. This paper discusses these elements and explores theories and empirical evidence about what constitutes intuitive expertise, and offers an account…

  1. Computational Evidence for the Smallest Boron Nanotube

    Institute of Scientific and Technical Information of China (English)

    Xian Jie LIN; Dong Ju ZHANG; Cheng Bu LIU

    2006-01-01

    The structure of boron nanotubes (BNTs) was found not to be limited to hexagonal pyramidal structures. Based on density functional theory calculations we provided evidence for the smallest boron nanotube, a geometrical analog of the corresponding carbon nanotube. As shown by our calculations, the smallest BNT possesses highly structural, dynamical, and thermal stability, which should be interest for attempts at its synthesis.

  2. 22 CFR 224.34 - Evidence.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Evidence. 224.34 Section 224.34 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 224... probative value is substantially outweighed by the danger of unfair prejudice, confusion of the issues,...

  3. 42 CFR 1005.17 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... danger of unfair prejudice, confusion of the issues, or by considerations of undue delay or needless..., wrongs or acts other than those at issue in the instant case is admissible in order to show motive... evidence is admissible regardless of whether the crimes, wrongs or acts occurred during the statute...

  4. 22 CFR 521.34 - Evidence.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Evidence. 521.34 Section 521.34 Foreign Relations BROADCASTING BOARD OF GOVERNORS IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 521.34... substantially outweighed by the danger of unfair prejudice, confusion of the issues, or by consideration...

  5. Behavioural activation: history, evidence and promise.

    Science.gov (United States)

    Kanter, Jonathan W; Puspitasari, Ajeng J; Santos, Maria M; Nagy, Gabriela A

    2012-05-01

    Behavioural activation holds promise to reduce the global burden of depression as a treatment approach that is effective, easy to teach, scalable and acceptable to providers and patients across settings and cultures. This editorial reviews the history of behavioural activation, what it is, current evidence for its use and future directions.

  6. [Evidence-based medicine: an epistemological approach].

    Science.gov (United States)

    Henao, Daniel Eduardo; Jaimes, Fabián Alberto

    2009-03-01

    Evidence-based medicine gathers physician's experience and the best scientific evidence to make medical decisions. This proposal has been widely promulgated by medical opinion leaders. Despite a large literature supporting this practice, a formal discussion has not been established regarding its epistemological consequences in daily medical work. The main proposal of evidence-based medicine consists of choosing the best medical decision according to the best available results from scientific studies. Herein, the goal was to highlight inappropriate application of the scientific method used by physics to clinical science. The inaccuracy resides in describing health and disease in strictly numeric equivalents that can be homogenized on a continuous scale. Finally, the authors consider each diseased human being as a complex system, unique and particular, and that this being is defined by an historical background as well as current actual context. Therefore, evidence-based medicine possesses certain limitations that must be recognized in order to to provide better health care to patients. PMID:19753837

  7. Evidence that Good Early Childhood Programs Work.

    Science.gov (United States)

    Schweinhart, Lawrence J.; Weikart, David P.

    1985-01-01

    Seven studies of the positive long- and short-term effects of good preschool programs on low-income youngsters provide evidence that such programs can be effective. The studies also reveal some of the problems faced by researchers in this field. (PGD)

  8. Distributed Leadership: According to the Evidence

    Science.gov (United States)

    Harris, Alma

    2008-01-01

    Purpose: This paper aims to provide an overview of the literature concerning distributed leadership and organisational change. The main purpose of the paper is to consider the empirical evidence that highlights a relationship between distributed leadership and organisational outcomes. Design/methodological approach: The paper draws on several…

  9. Evidence-Based Chinese Medicine for Hypertension

    Directory of Open Access Journals (Sweden)

    Jie Wang

    2013-01-01

    Full Text Available Hypertension is an important worldwide public -health challenge with high mortality and disability. Due to the limitations and concerns with current available hypertension treatments, many hypertensive patients, especially in Asia, have turned to Chinese medicine (CM. Although hypertension is not a CM term, physicians who practice CM in China attempt to treat the disease using CM principles. A variety of approaches for treating hypertension have been taken in CM. For seeking the best evidence of CM in making decisions for hypertensive patients, a number of clinical studies have been conducted in China, which has paved the evidence-based way. After literature searching and analyzing, it appeared that CM was effective for hypertension in clinical use, such as Chinese herbal medicine, acupuncture, moxibustion, cupping, qigong, and Tai Chi. However, due to the poor quality of primary studies, clinical evidence is still weak. The potential benefits and safety of CM for hypertension still need to be confirmed in the future with well-designed RCTs of more persuasive primary endpoints and high-quality SRs. Evidence-based Chinese medicine for hypertension still has a long way to go.

  10. Fossil evidence of the zygomycetous fungi

    NARCIS (Netherlands)

    Krings, M.; Taylor, T.N.; Dotzler, N.

    2013-01-01

    Molecular clock data indicate that the first zygomycetous fungi occurred on Earth during the Precambrian, however, fossil evidence of these organisms has been slow to accumulate. In this paper, the fossil record of the zygomycetous fungi is compiled, with a focus on structurally preserved Carbonifer

  11. Evidence Based Education Request Desk. EBE #359

    Science.gov (United States)

    Regional Educational Laboratory Southeast, 2008

    2008-01-01

    This Evidence Based Education (EBE) response describes characteristics of graduation coach initiatives in three states (Georgia, Alabama, and California). Regional Educational Laboratory (REL) Southeast has received over 19 requests for information on various initiatives, programs or research related to improving graduation rates. For example, the…

  12. Evidence Based Education Request Desk. EBE #555

    Science.gov (United States)

    Regional Educational Laboratory Southeast, 2009

    2009-01-01

    This Evidence Based Education (EBE) Request seeks to provide an overview of recent research regarding school improvement and reform with special concentration on turning around chronically low-performing schools. The response is divided into four main sections: Research on Effective Methods for Turning Around Low-Performing Schools, Frameworks for…

  13. Evidence Based Education Request Desk. EBE #510

    Science.gov (United States)

    Regional Educational Laboratory Southeast, 2009

    2009-01-01

    This Evidence Based Education (EBE) request focused on research-supported vocabulary interventions for middle elementary students. Limited vocabulary is an important factor in underachievement of children in disadvantaged homes. Children with larger vocabularies find reading easier, read more widely, and do better in school (Lubliner & Smetana,…

  14. Evidence Based Education Request Desk. EBE #741

    Science.gov (United States)

    Regional Educational Laboratory Southeast, 2010

    2010-01-01

    This Evidence Based Education (EBE) request asks for information relating to funding for virtual schools. The EBE Request Desk was asked to provide a scan of states for information on how they fund virtual schools and what the current funding levels are (most current year for which such data is available). This paper provides answers to this…

  15. Evidence Based Education Request Desk. EBE #798

    Science.gov (United States)

    Regional Educational Laboratory Southeast, 2011

    2011-01-01

    Evidence Based Education (EBE) #555 was in response to the request "Is there any new compelling research for turning around low-performing schools?" The articles included in that document are on target, but include articles through 2009. This EBE Request seeks to provide an updated review of recent research (2009-present) regarding school…

  16. Evidence-Based Treatment of Maisonneuve Fractures

    NARCIS (Netherlands)

    S.A. Stufkens; M.P.J. van den Bekerom; J.N. Doornberg; C.N. van Dijk; P. Kloen

    2011-01-01

    The objective of the current study was to review the published clinical evidence available for the treatment of Maisonneuve fractures. Medline via PubMed, Orthopaedic Trauma Association (OTA) annual meetings' abstracts archives Web site, Embase, the Cochrane Database of Systematic Reviews, and the C

  17. Cyberbullying: Incidence, Evidence and Solutions : Video Presentation

    OpenAIRE

    O'Neill, Brian

    2015-01-01

    Presentation by Professor Brian O'Neill (DIT), "Cyberbullying: Incidence, Evidence and Solutions". Delivered at Dublin Institute of Technology, Aungier St, Dublin 2 on 26th June 2015. - See more at: http://lttc.dit.ie/lttc/elearning/elearningsummerschool/pastsummerschools/summerschool2015/elss15videopresentations/#sthash.cge2gwYH.dpuf

  18. Level of evidence in hand surgery

    Directory of Open Access Journals (Sweden)

    Rosales Roberto S

    2012-12-01

    Full Text Available Abstract Background Few investigations have been done to analyze the level of evidence in journals related to hand surgery, compared to other related research fields. The objective of this study was to assess the level of evidence of the clinical research papers published in the Ibero-american (RICMA, the European (JHSE and American (JHSA Journals of Hand Surgery. Methods A total of 932 clinical research papers published between 2005 and 2009 (RICMA 60, JHSE 461, and JHSA 411 were reviewed. Two independent observers classified the level of evidence based on the Oxford International Classification, 5 being the lowest level and 1 the highest level. The observed frequencies of the level of evidence for each journal were compared with the expected frequencies by a chi-square (χ 2 test for categorical variables with a significance level of 0.05. Results Inter-observer agreement analysis showed a Kappa of 0.617. Intra-observer agreement analysis presented a Kappa of 0.66 for the observer 1, and a Kappa of 0.751 for the observer 2. More than 80% of the papers in RICMA and JHSE and a 67.6% in the JHSA presented a level of 4. No level 1 or 2 studies were published in RICMA, compared to JHSE (0.9% level 1 and 5.0% level 2 and JHSA (8.3% level 1 and 10% level 2. The percentage of papers with level 3 published in RICMA (16.7% was higher compared to the JHSE (11.1% and the JHSA (14.1%. All the results were statistically significant (χ2=63.945; p Conclusions The level of evidence in hand surgery is dependent on the type of journal; being the highest level evidence papers those published in the JHSA, followed by the JHSE and finally the RICMA. Knowing the status of the level of evidence published in hand surgery is the starting point to face the challenges of improving the quality of our clinical research

  19. [Psychosis and addiction: The evidence cemetery].

    Science.gov (United States)

    Potvin, Stéphane; Lalonde, Martin

    2014-01-01

    Objectives The comorbidity between psychosis and substance use has attracted wide attention over the years, and a vast literature is now available for meta-analytic treatment. In the field, a majority of authors assume that cannabis smoking is a risk factor for psychosis, that substance abuse is highly prevalent in schizophrenia, that substance abuse worsens the prognosis of schizophrenia, and that integrated treatments have greater efficacy than treatment-as-usual for this complex population. The objective of the current article is to review the meta-analyses that have been published in the comorbidity field in order to determine if the above-mentioned assumptions are substantiated by evidence or not. Methods A search of the literature was performed using PubMed, PsycINFO and EMBASE. The literature search retrieved a total of 25 systematic quantitative reviews, addressing the following issues: etiology, age at onset, prevalence rates, cognition, treatment, as well as psychiatric, neurologic and functional outcomes. Results Evidence shows that the prevalence of tobacco smoking, cannabis smoking and alcohol use is elevated in psychosis. However, this prevalence is likely to be over-estimated since studies have been performed in clinical settings rather than the general population. Reliable evidence also suggests that cannabis smoking is a risk factor for psychosis outcomes. However, the association is rather small and it remains difficult to draw an unequivocal public health message from this literature. In the same vein, evidence suggests that cannabis smoking is associated with an earlier age at onset of psychosis. However, this observation is derived from cross-sectional studies, not longitudinal ones; thus, no undisputable claims on causality can be made from them. On clinical grounds, some evidence also suggests that substance use is associated with self-harm, increased positive and depressive symptoms in psychosis patients, but this evidence is derived from

  20. Concurrency revisited: increasing and compelling epidemiological evidence

    Directory of Open Access Journals (Sweden)

    Mah Timothy L

    2011-06-01

    Full Text Available Abstract Multiple sexual partnerships must necessarily lie at the root of a sexually transmitted epidemic. However, that overlapping or concurrent partnerships have played a pivotal role in the generalized epidemics of sub-Saharan Africa has been challenged. Much of the original proposition that concurrent partnerships play such a role focused on modelling, self-reported sexual behaviour data and ethnographic data. While each of these has definite merit, each also has had methodological limitations. Actually, more recent cross-national sexual behaviour data and improved modelling have strengthened these lines of evidence. However, heretofore the epidemiologic evidence has not been systematically brought to bear. Though assessing the epidemiologic evidence regarding concurrency has its challenges, a careful examination, especially of those studies that have assessed HIV incidence, clearly indicates a key role for concurrency. Such evidence includes: 1 the early and dramatic rise of HIV infection in generalized epidemics that can only arise from transmission through rapid sequential acute infections and thereby concurrency; 2 clear evidence from incidence studies that a major portion of transmission in the population occurs via concurrency both for concordant negative and discordant couples; 3 elevation in risk associated with partner's multiple partnering; 4 declines in HIV associated with declines in concurrency; 5 bursts and clustering of incident infections that indicate concurrency and acute infection play a key role in the propagation of epidemics; and 6 a lack of other plausible explanations, including serial monogamy and non-sexual transmission. While other factors, such as sexually transmitted infections, other infectious diseases, biological factors and HIV sub-type, likely play a role in enhancing transmission, it appears most plausible that these would amplify the role of concurrency rather than alter it. Additionally, critics of

  1. Micronutrients and cancer aetiology: the epidemiological evidence.

    Science.gov (United States)

    Key, T

    1994-11-01

    Micronutrient deficiencies occur most commonly in poor countries and, therefore, are most likely to be associated with cancers common in these countries. Epidemiological studies are hampered by inaccurate measurement of micronutrient intake and by the correlations between intakes of many nutrients. The strongest evidence for a protective effect of micronutrients is for oesophageal cancer. The identity of the micronutrients is not certain, but may include retinol, riboflavin, ascorbic acid and Zn; alcohol, smoking and dietary nitrosamines increase the risk for oesophageal cancer. For stomach cancer there is good evidence that fruit and vegetables are protective. The protective effect of these foods might be largely due to ascorbic acid, but other nutrients and non-nutrients may also be important; the risk for stomach cancer is increased by salt, some types of preserved foods, and by infection of the stomach with the bacterium Helicobacter pylori. The risk for lung cancer appears to be reduced by a high intake of fruit and vegetables, but it is not clear which agents are responsible and the major cause of lung cancer is cigarette smoking. Diet is probably the major determinant of the risk for colo-rectal cancer; there is evidence that fruit and vegetables and fibre reduce risk and that meat and animal fat increase risk, but there is no convincing evidence that these relationships are mediated by micronutrients. The risk for cervical cancer is inversely related to fruit and vegetable consumption and, therefore, to consumption of carotenoids and ascorbic acid, but the major cause of this cancer is human papillomavirus and it is not yet clear whether the dietary associations indicate a true protective effect or whether they are due to confounding by other variables. The evidence that micronutrients are important in the aetiology of either breast cancer or prostate cancer is weak, but the possible roles of 1,25-dihydroxycholecalciferol and alpha-tocopherol in prostate

  2. Nutrition and sarcopenia: evidence for an interaction.

    Science.gov (United States)

    Millward, D Joe

    2012-11-01

    Nutritional interventions that might influence sarcopenia, as indicated by literature reporting on sarcopenia per se as well as dynapenia and frailty, are reviewed in relation to potential physiological aetiological factors, i.e. inactivity, anabolic resistance, inflammation, acidosis and vitamin D deficiency. As sarcopenia occurs in physically active and presumably well-nourished populations, it is argued that a simple nutritional aetiology is unlikely and unequivocal evidence for any nutritional influence is extremely limited. Dietary protein is probably the most widely researched nutrient but only for frailty is there one study showing evidence of an aetiological influence and most intervention studies with protein or amino acids have proved ineffective with only a very few exceptions. Fish oil has been shown to attenuate anabolic resistance of muscle protein synthesis in one study. There is limited evidence for a protective influence of antioxidants and inducers of phase 2 proteins on sarcopenia, dynapenia and anabolic resistance in human and animal studies. Also fruit and vegetables may protect against acidosis-induced sarcopenia through their provision of dietary potassium. While severe vitamin D deficiency is associated with dynapenia and sarcopenia, the evidence for a beneficial influence of increasing vitamin D status above the severe deficiency level is limited and controversial, especially in men. On this basis there is insufficient evidence for any more specific nutritional advice than that contained in the general healthy lifestyle-healthy diet message: i.e. avoiding inactivity and low intakes of food energy and nutrients and maintain an active lifestyle with a diet providing a rich supply of fruit and vegetables and frequent oily fish.

  3. Can Scholarly Communication be Evidence Based? (Editorial

    Directory of Open Access Journals (Sweden)

    Denise Koufogiannakis

    2010-12-01

    Full Text Available This issue of Evidence Based Library and Information Practice includes three papers from the Evidence Based Scholarly Communication Conference (EBSCC that took place in March 2010i. Kroth, Philips and Eldredge have written a commentary that gives an overview of the conference, and introduces us to the research papers that were presented. As well, two research presentations from the conference appear in this issue, an article by Donahue about a potential new method of communicating between scholars, and a paper by Gilliland in our Using Evidence in Practice section, detailing a library’s Open Access Day preparations.Kroth, Philips and Eldredge note that “The EBSCC brought together librarians and information specialists to share evidence-based strategies for developing effective local scholarly communication support and training and, hopefully, form new coalitions to address this topic at a local and national level.” (p 108. This conference focused on translational medicine, and looked at how to promote new methods of scholarly communication, partially through the inclusion of research papers at the conference.The inclusion of these articles and the evidence based focus of the EBSCC conference, made me ask myself, can scholarly communication be evidence based? At its core, scholarly communication is anything but a scientific issue. It is charged with emotion; from authors, publishers, librarians and others involved in the business of publishing. The recent shift to look at new models of scholarly communication has been a threat to many of the established models and sparked much debate in the academic world, especially in relation to open access. In her 2006 EBLIP commentary on evidence based practice and open access, Morrison notes, “Open Access and evidence based librarianship are a natural combination” (p. 49, and outlines her perspective on many of the reasons why. Debate continues to rage, however, regarding how authors should

  4. On the Assessment Standardization for TCM Clinical Evidence

    Institute of Scientific and Technical Information of China (English)

    Wang Yingying; Yang Jinsheng

    2008-01-01

    @@ Nowadays,the evidence-based medicine has been widely used for assessment of TCM.The assessment based on clinical evidence and the quality is the core of evidence-based medicine.However,the evidencerating methods adopted in the modern medical system are only applicable in a certain degree to the assessment of TCM clinicaI evidence.

  5. 29 CFR 18.103 - Rulings on evidence.

    Science.gov (United States)

    2010-07-01

    ... OF ADMINISTRATIVE LAW JUDGES Rules of Evidence § 18.103 Rulings on evidence. (a) Effect of erroneous ruling. Error may not be predicated upon a ruling which admits or excludes evidence unless a substantial... 29 Labor 1 2010-07-01 2010-07-01 true Rulings on evidence. 18.103 Section 18.103 Labor Office...

  6. 29 CFR 458.78 - Rules of evidence.

    Science.gov (United States)

    2010-07-01

    ... OF CONDUCT Hearing and Related Matters § 458.78 Rules of evidence. The technical rules of evidence do not apply. Any evidence may be received, except that an Administrative Law Judge may exclude any... 29 Labor 2 2010-07-01 2010-07-01 false Rules of evidence. 458.78 Section 458.78 Labor...

  7. 12 CFR 1102.30 - Rules of evidence.

    Science.gov (United States)

    2010-01-01

    ... applicable law. (2) Evidence that would be admissible under the Federal Rules of Evidence is admissible in a... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Rules of evidence. 1102.30 Section 1102.30... Practice for Proceedings § 1102.30 Rules of evidence. (a) In general. (1) Except as is otherwise set...

  8. 20 CFR 220.45 - Providing evidence of disability.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Providing evidence of disability. 220.45... DETERMINING DISABILITY Evidence of Disability § 220.45 Providing evidence of disability. (a) General. The claimant for a disability annuity is responsible for providing evidence of the claimed disability and...

  9. Evidence-Based Practice Guidelines and School Nursing

    Science.gov (United States)

    Adams, Susan; McCarthy, Ann Marie

    2007-01-01

    The use of evidence-based practice (EBP) has become the standard of health care practice. Nurses are expected to use best evidence on a wide range of topics, yet most nurses have limited time, resources, and/or skills to access and evaluate the quality of research and evidence needed to practice evidence-based nursing. EBP guidelines allow nurses…

  10. Shaping accountabilities for erroneously enacted environmental evidence

    DEFF Research Database (Denmark)

    Lippert, Ingmar

    of accountability: first, the company was performing itself as a socially and environmentally accountable and responsible "corporate citizen"; second, the company was inhabiting a discourse of evidence-based decision-making, requiring the evidence to be produced accountably. I analyse a limited set of ethnographic...... vignettes of situated work practice that (con)figured the company's accounting for their carbon emissions. Common to all these situations was that the environmental realities enacted have been categorised by some members as erroneous or as not good enough. In this paper I am interested, thence......)possibilities for particular modes of relating to, responding to and accounting for the various actants involved in the work, including to/for the discursively imagined "real" carbon....

  11. Evidence and research in rectal cancer

    International Nuclear Information System (INIS)

    The main evidences of epidemiology, diagnostic imaging, pathology, surgery, radiotherapy, chemotherapy and follow-up are reviewed to optimize the routine treatment of rectal cancer according to a multidisciplinary approach. This paper reports on the knowledge shared between different specialists involved in the design and management of the multidisciplinary ESTRO Teaching Course on Rectal Cancer. The scenario of ongoing research is also addressed. In this time of changing treatments, it clearly appears that a common standard for large heterogeneous patient groups have to be substituted by more individualised therapies based on clinical-pathological features and very soon on molecular and genetic markers. Only trained multidisciplinary teams can face this new challenge and tailor the treatments according to the best scientific evidence for each patient

  12. History and evidence regarding hydrostatic shock

    CERN Document Server

    Courtney, Michael; 10.1227/NEU.0b013e3182041992

    2011-01-01

    This paper reviews the history and evidence related to remote wounding effects of ballistic pressure waves imparted to tissue by the impact of a bullet. Such remote effects are often referred to as hydraulic or hydrostatic shock. In spite of considerable published evidence and a long history, some medical professionals continue to regard the ability of a bullet to injure tissue that is not directly crushed or stretched as mythical (Jandial R, Reichwage B, Levy M, Duenas V, Sturdivan L. Ballistics for the neurosurgeon. Neurosurgery. 2008:62:472-480.) Early references to these effects date to the 19th century; however, compelling experimental support and medical findings in human case studies did not become available until the late 20th and early 21st century.

  13. Evidence-Based Education in Plastic Surgery.

    Science.gov (United States)

    Johnson, Shepard P; Chung, Kevin C; Waljee, Jennifer F

    2015-08-01

    Educational reforms in resident training have historically been driven by reports from medical societies and organizations. Although educational initiatives are well intended, they are rarely supported by robust evidence. The Accreditation Council for Graduate Medical Education recently introduced competency-based training, a form of outcomes-based education that has been used successfully in nonmedical professional vocations. This initiative has promise to advance the quality of resident education, but questions remain regarding implementation within plastic surgery. In particular, how will competency-based training impact patient outcomes, and will the methodologies used to assess competencies (i.e., milestones) be accurate and validated by literature? This report investigates resident educational reform and the need for more evidence-based educational initiatives in plastic surgery training.

  14. Creative teaching an evidence-based approach

    CERN Document Server

    Sale, Dennis

    2015-01-01

    This book contains an evidence-based pedagogic guide to enable any motivated teaching/training professional to be able to teach effectively and creatively. It firstly summarises the extensive research field on human psychological functioning relating to learning and how this can be fully utilised in the design and facilitation of quality learning experiences. It then demonstrates what creativity actually 'looks like' in terms of teaching practices, modelling the underpinning processes of creative learning design and how to apply these in lesson planning. The book, having established an evidence-based and pedagogically driven approach to creative learning design, extensively focuses on key challenges facing teaching professionals today. These include utilising information technologies in blended learning formats, differentiating instruction, and developing self-directed learners who can think well. The main purpose of the book is to demystify what it means to teach creatively, explicitly demonstrating the pr...

  15. Digital Evidence Education in Schools of Law

    Directory of Open Access Journals (Sweden)

    Aaron Alva

    2012-06-01

    Full Text Available An examination of State of Connecticut v. Julie Amero provides insight into how a general lack of understanding of digital evidence can cause an innocent defendant to be wrongfully convicted. By contrast, the 101-page opinion in Lorraine v. Markel American Insurance Co. provides legal precedence and a detailed consideration for the admission of digital evidence. An analysis of both cases leads the authors to recommend additions to Law School curricula designed to raise the awareness of the legal community to ensure such travesties of justice, as in the Amero case, don’t occur in the future. Work underway at the University of Washington designed to address this deficiency is discussed.

  16. Evidence Based Education: un quadro storico

    Directory of Open Access Journals (Sweden)

    Giuliano Vivanet

    2013-08-01

    Full Text Available Nel corso dell’ultimo decennio, nel pensiero pedagogico anglosassone, si è affermata una cultura dell’evidenza cui ci si riferisce con l’espressione “evidence based education” (EBE. Secondo tale prospettiva, le decisioni in ambito educativo dovrebbero essere assunte sulla base delle conoscenze che la ricerca empirica offre in merito alla minore o maggiore efficacia delle differenti opzioni didattiche. Si tratta di un approccio (denominato “evidence based practice” che ha origine in ambito medico e che in seguito ha trovato applicazione in differenti domini delle scienze sociali. L’autore presenta un quadro introduttivo all’EBE, dando conto delle sue origini e dei differenti significati di cui è portatrice.

  17. 2013 Nutrition Risk Evidence Review Panel. Evidence Review for: The Risk Factor of Inadequate Nutrition

    Science.gov (United States)

    2014-01-01

    The 2013 Nutrition Risk Standing Review Panel (from here on referred to as the SRP) met for a site visit in Houston, TX on November 20 - 21, 2013. The SRP reviewed the new Evidence Report for the Risk Factor of Inadequate Nutrition (from here on referred to as the 2013 Nutrition Evidence Report), as well as the Research Plan for this Risk. Overall, the SRP thinks the well-qualified research team has compiled an excellent summary of background information in the 2013 Nutrition Evidence Report. The SRP would like to commend the authors in general and particularly note that while the 2013 Nutrition Evidence Report has been written using a single nutrient approach, the research plan takes a much more integrated and physiologically based approach.

  18. Education and Economic Development: Evidence from China

    OpenAIRE

    Shuanglin Lin

    1997-01-01

    Evidence from thirty Chinese provinces indicates that education is crucial for economic development. Provinces with the higher average years of schooling in the intial year have higher growth rates of real per capita GDP in the subsequent year. Provinces with higher literacy rates and higher average years of schooling in the initial year experienced a faster decline of the employment share of agriculture in the subsequent year than provinces with lower literacy rates and lower average years o...

  19. Evidence in Liability Law - an introduction

    OpenAIRE

    Vandenbussche, Wannes

    2015-01-01

    The main goal of this introduction is to highlight some characteristics regarding the administration of evidence in liability law, which are common in some European legal systems. First, I will focus on the proof of basic constituents in fault liability claim. Second, I was not able to analyze all European legal systems, so I will limit this presentation to five legal systems (Belgium, Netherlands, Germany, France, and Switzerland).

  20. Evidence Regarding the Treatment of Denture Stomatitis.

    Science.gov (United States)

    Yarborough, Alexandra; Cooper, Lyndon; Duqum, Ibrahim; Mendonça, Gustavo; McGraw, Kathleen; Stoner, Lisa

    2016-06-01

    Denture stomatitis is a common inflammatory condition affecting the mucosa underlying complete dentures. It is associated with denture microbial biofilm, poor denture hygiene, poor denture quality, and nocturnal denture use. Numerous treatment methodologies have been used to treat stomatitis; however, a gold standard treatment has not been identified. The aim of this systematic review is to report on the current knowledge available in studies representing a range of evidence on the treatment of denture stomatitis.

  1. Computational mate choice: theory and empirical evidence.

    Science.gov (United States)

    Castellano, Sergio; Cadeddu, Giorgia; Cermelli, Paolo

    2012-06-01

    The present review is based on the thesis that mate choice results from information-processing mechanisms governed by computational rules and that, to understand how females choose their mates, we should identify which are the sources of information and how they are used to make decisions. We describe mate choice as a three-step computational process and for each step we present theories and review empirical evidence. The first step is a perceptual process. It describes the acquisition of evidence, that is, how females use multiple cues and signals to assign an attractiveness value to prospective mates (the preference function hypothesis). The second step is a decisional process. It describes the construction of the decision variable (DV), which integrates evidence (private information by direct assessment), priors (public information), and value (perceived utility) of prospective mates into a quantity that is used by a decision rule (DR) to produce a choice. We make the assumption that females are optimal Bayesian decision makers and we derive a formal model of DV that can explain the effects of preference functions, mate copying, social context, and females' state and condition on the patterns of mate choice. The third step of mating decision is a deliberative process that depends on the DRs. We identify two main categories of DRs (absolute and comparative rules), and review the normative models of mate sampling tactics associated to them. We highlight the limits of the normative approach and present a class of computational models (sequential-sampling models) that are based on the assumption that DVs accumulate noisy evidence over time until a decision threshold is reached. These models force us to rethink the dichotomy between comparative and absolute decision rules, between discrimination and recognition, and even between rational and irrational choice. Since they have a robust biological basis, we think they may represent a useful theoretical tool for

  2. Rational Addiction Evidence From Carbonated Soft Drinks

    OpenAIRE

    Xiaoou, Liu

    2009-01-01

    This paper applies the Becker-Murphy (1988) theory of rational addiction to the case of carbonated soft drinks, using a time-varying parameter model and scanner data from 46 U.S. cities. Empirical results provide strong evidence that carbonated soft drinks are rationally addictive, thus opening the door to taxation and regulation. Taking rational addition into account, estimated demand elasticities are much lower than previous estimates using scanner data.

  3. Bank regulations and income inequality: Empirical evidence

    OpenAIRE

    Manthos, Delis; Iftekhar, Hasan; Pantelis, Kazakis

    2010-01-01

    This paper provides cross-country evidence that variations in bank regulatory policies result in differences in income distribution. In particular, the overall liberalization of banking systems decreases the Gini coefficient and the Theil index significantly. However, this effect fades away for countries with low levels of economic and institutional development and for market-based economies. Among the different liberalization policies, the most significant negative effect on inequality is th...

  4. New Evidence for Fremont Adaptive Diversity

    OpenAIRE

    Simms, Steven R.

    1986-01-01

    Excavations in the Sevier Desert of western Utah (Fig. 1) have produced architectural evidence for temporary habitation in small brush, wickiup-type structures between A.D. 1000 and 1100 by people with Fremont material culture. The inventory includes Fremont ceramics, a single corn cob, and projectile points common to, but not exclusive to, Fremont sites (Cottonwood Triangular, Rose Spring Cornernotched, and Desert Side-notched). The site broadens our understanding of Fremont architectural an...

  5. Productivity effects of organizational change: microeconometric evidence

    OpenAIRE

    Bertschek, Irene; Kaiser, Ulrich

    2001-01-01

    This paper analyzes the relationship between investment in information and communication technologies (ICT), non-ICT-investment, labor productivity and workplace reorganization. Firms are assumed to reorganize workplaces if the productivity gains arising from workplace reorganization exceed the associated reorganization costs. Two different types of organizational change are considered : introduction of group-work and flattening of hierarchies. Empirical evidence is provided for a sample of 4...

  6. Computational mate choice: theory and empirical evidence.

    Science.gov (United States)

    Castellano, Sergio; Cadeddu, Giorgia; Cermelli, Paolo

    2012-06-01

    The present review is based on the thesis that mate choice results from information-processing mechanisms governed by computational rules and that, to understand how females choose their mates, we should identify which are the sources of information and how they are used to make decisions. We describe mate choice as a three-step computational process and for each step we present theories and review empirical evidence. The first step is a perceptual process. It describes the acquisition of evidence, that is, how females use multiple cues and signals to assign an attractiveness value to prospective mates (the preference function hypothesis). The second step is a decisional process. It describes the construction of the decision variable (DV), which integrates evidence (private information by direct assessment), priors (public information), and value (perceived utility) of prospective mates into a quantity that is used by a decision rule (DR) to produce a choice. We make the assumption that females are optimal Bayesian decision makers and we derive a formal model of DV that can explain the effects of preference functions, mate copying, social context, and females' state and condition on the patterns of mate choice. The third step of mating decision is a deliberative process that depends on the DRs. We identify two main categories of DRs (absolute and comparative rules), and review the normative models of mate sampling tactics associated to them. We highlight the limits of the normative approach and present a class of computational models (sequential-sampling models) that are based on the assumption that DVs accumulate noisy evidence over time until a decision threshold is reached. These models force us to rethink the dichotomy between comparative and absolute decision rules, between discrimination and recognition, and even between rational and irrational choice. Since they have a robust biological basis, we think they may represent a useful theoretical tool for

  7. How to teach evidence-based surgery.

    Science.gov (United States)

    Fingerhut, Abe; Borie, Frédéric; Dziri, Chadli

    2005-05-01

    The objectives of teaching evidence-based surgery (EBS) are to inform and convince that EBS is a method of interrogation, reasoning, appraisal, and application of information to guide physicians in their decisions to best treat their patients. Asking the right, answerable questions, translating them into effective searches for the best evidence, critically appraising evidence for its validity and importance, and then integrating EBS with their patients' values and preferences are daily chores for all surgeons. Teaching and learning EBS should be patient-centered, learner-centered, and active and interactive. The teacher should be a model for students to become an expert clinician who is able to match and take advantage of the clinical setting and circumstances to ask and to answer appropriate questions. The process is multistaged. Teaching EBS in small groups is ideal. However, it is time-consuming for the faculty and must be clearly and formally structured. As well, evidence-based medicine (EBM) courses must cater to local institutional needs, must receive broad support from the instructors and the providers of information (librarians and computer science faculty), use proven methodologies, and avoid scheduling conflicts. In agreement with others, we believe that the ideal moment to introduce the concepts of EBM into the curriculum of the medical student is early, during the first years of medical school. Afterward, it should be continued every year. When this is not the case, as in many countries, it becomes the province of the surgeon in teaching hospitals, whether they are at the university, are university-affiliated, or not, to fulfill this role.

  8. Analysis of evidence of Mars life

    CERN Document Server

    Levin, Gilbert V

    2007-01-01

    Gillevinia straata, the scientific name [1, 2] recognizing the first extraterrestrial living form ever nomenclated, as well as the existence of a new biological kingdom, Jakobia, in a new biosphere -Marciana- of what now has become the living system Solaria, is grounded on old evidence reinterpreted in the light of newly acquired facts. The present exposition provides a summary overview of all these grounds, outlined here as follows. A more detailed paper is being prepared for publication.

  9. New Evidence on Teacher Labor Supply

    OpenAIRE

    Mimi Engel; Brian A. Jacob

    2011-01-01

    Recent evidence on the large variance in teacher effectiveness has spurred renewed interest in teacher labor market policies. A substantial body of prior research documents that more highly qualified teachers tend to work in more advantaged schools, although this literature cannot determine the relative importance of supply versus demand factors in generating this equilibrium outcome. To isolate the importance of teacher labor supply, we attended three large teacher job fairs in Chicago durin...

  10. Digital natives: where is the evidence?

    OpenAIRE

    Helsper, Ellen; Eynon, Rebecca

    2010-01-01

    Generational differences are seen as the cause of wide shifts in our ability to engage with technologies and the concept of the digital native has gained popularity in certain areas of policy and practice. This paper provides evidence, through the analysis of a nationally representative survey in the UK, that generation is only one of the predictors of advanced interaction with the Internet. Breadth of use, experience, gender and educational levels are also important, indeed in some cases mor...

  11. Distinction between forensic evidence and dermatological findings.

    Science.gov (United States)

    Hammer, U; Boy, D; Rothaupt, D; Büttner, A

    2015-07-01

    The external examination after death requires knowledge in forensics/pathology, dermatology, as well as associated diseases and age-related alterations of the skin. This article highlights some findings with forensic evidence versus dermatological findings. The lectures in forensic medicine should be structured interdisciplinarily, especially to dermatology, internal medicine, surgery, pathology, and toxicology in order to train the overlapping skills required for external and internal postmortem examinations.

  12. Immigration and Housing Booms: Evidence from Spain

    OpenAIRE

    Gonz??lez Luna, Libertad; Ortega, Francesc

    2009-01-01

    We estimate empirically the effect of immigration on house prices and residential construction activity in Spain over the period 1998-2008. This decade is characterized by both a spectacular housing market boom and a stunning immigration wave. We exploit the variation in immigration across Spanish provinces and construct an instrument based on the historical location patterns of immigrants by country of origin. The evidence points to a sizeable causal effect of immigration on b...

  13. Inferring identify from DNA profile evidence.

    OpenAIRE

    Balding, D. J.; Donnelly, P.

    1995-01-01

    The controversy over the interpretation of DNA profile evidence in forensic identification can be attributed in part to confusion over the mode(s) of statistical inference appropriate to this setting. Although there has been substantial discussion in the literature of, for example, the role of population genetics issues, few authors have made explicit the inferential framework which underpins their arguments. This lack of clarity has led both to unnecessary debates over ill-posed or inappropr...

  14. Reciprocity in Organisations - Evidence from the WERS

    OpenAIRE

    Englmaier, Florian; Kolaska, Thomas; Stephen G. Leider

    2015-01-01

    Recent laboratory evidence suggests that social preferences may affect contractual outcomes under moral hazard. In accordance with previous research, this paper uses written personality tests for job candidates as a proxy for whether firms care about personality traits of employees, in particular whether these employees are inclined towards reciprocity. Using the British Workplace Employment Relations Survey 2004 (WERS) we find that behavior of employers and employees is consistent with the p...

  15. Evidence for supplemental treatments in androgenetic alopecia.

    Science.gov (United States)

    Famenini, Shannon; Goh, Carolyn

    2014-07-01

    Currently, topical minoxidil and finasteride are the only treatments that have been FDA approved for the treatment of female pattern hair loss and androgenetic alopecia. Given the incomplete efficacy and sife effect profile of these medications, some patients utilize alternative treatments to help improve this condition. In this review, we illustrate the scientific evidence underlying the efficacy of these alternative approaches, including biotin, caffeine, melatonin, a marine extract, and zinc. PMID:25007363

  16. Allergic rhinitis: evidence for impact on asthma

    OpenAIRE

    Thomas, Mike

    2006-01-01

    Background This paper reviews the current evidence indicating that comorbid allergic rhinitis may have clinically relevant effects on asthma. Discussion Allergic rhinitis is very common in patients with asthma, with a reported prevalence of up to 100% in those with allergic asthma. While the temporal relation of allergic rhinitis and asthma diagnoses can be variable, the diagnosis of allergic rhinitis often precedes that of asthma. Rhinitis is an independent risk factor for the subsequent dev...

  17. Evidence Regarding the Treatment of Denture Stomatitis.

    Science.gov (United States)

    Yarborough, Alexandra; Cooper, Lyndon; Duqum, Ibrahim; Mendonça, Gustavo; McGraw, Kathleen; Stoner, Lisa

    2016-06-01

    Denture stomatitis is a common inflammatory condition affecting the mucosa underlying complete dentures. It is associated with denture microbial biofilm, poor denture hygiene, poor denture quality, and nocturnal denture use. Numerous treatment methodologies have been used to treat stomatitis; however, a gold standard treatment has not been identified. The aim of this systematic review is to report on the current knowledge available in studies representing a range of evidence on the treatment of denture stomatitis. PMID:27062660

  18. What counts as evidence of inclusive education?

    OpenAIRE

    Florian, Lani

    2014-01-01

    Inclusive education takes many forms, raising important questions about what constitutes good practice, what counts as evidence of such practice and how it can be known. This paper responds to Göransson and Nilholm’s critical review of research on inclusive education by considering why a clear working definition of inclusion has thus far proved elusive. It agrees that new types of studies and more theoretically informed work is needed if knowledge about inclusive education is to advance. A fr...

  19. Evidence for Regge shrinkage in $\\pi$ exchange

    CERN Document Server

    Estabrooks, P G

    1972-01-01

    The authors review the possible ways of determining the Regge behaviour of pi exchange from the data and conclude that the most reliable way is to study rho /sup H//sub 00/d sigma /dt for pi /sup - /p to rho degrees n. Using such data evidence is found for a pion trajectory of conventional Regge slope. The authors also isolate the pion trajectory using data for gamma p to omega p. (22 refs).

  20. New evidence on ownership structures in Germany

    OpenAIRE

    Köke, Jens

    1999-01-01

    Ownership structures are an important element of the theory explaining corporate governance. This study presents detailed descriptive evidence on the ownership structures of German manufacturing firms. It addresses several shortcomings of the previous German empirical literature: First, we study all legal forms of a Kapitalgesellschaft, firms that generally have a separation of ownership and control. We do not focus exclusively on the listed Aktiengesellschaft (AG) but include many non-listed...

  1. EVIDENCE FOR COMET STORMS IN METEORITE AGES

    Energy Technology Data Exchange (ETDEWEB)

    Perlmutter, S.; Muller, R.A.

    1987-10-01

    Clustering of cosmic-ray exposure ages of H chondritic meteorites occurs at 7 {+-} 3 and 30 {+-} 6 Myr ago. There is independent evidence that comet storms have occurred at the same times, based on the fossil record of family and genus extinctions, impact craters and glass, and geomagnetic reversals. We suggest that H chondrites were formed by the impact of shower comets on asteroids. The duration of the most recent comet shower was {le} 4 Myr, in agreement with storm theory.

  2. Evidence of portuguese stock market abnormal returns

    OpenAIRE

    Duarte, Elisabete Mendes; Oliveira, Lisete Trindade

    2011-01-01

    According to the stock market efficiency theory, it is not possible to consistently beat the market. However, technical analysis is more and more spread as an efficient way to achieve abnormal returns. In fact there is evidence that momentum investing strategies provide abnormal returns in different stock markets, Jegadeesh, N. and Titman, S. (1993), George, T. and Hwang, C. (2004) and Du, D. (2009). In this work we study if like other markets, the Portuguese stock market also allows to obtai...

  3. Marital assortment and phenotypic convergence: longitudinal evidence.

    Science.gov (United States)

    Caspi, A; Herbener, E S

    1993-01-01

    This study provides a direct test of whether the observed similarity of spouses is due to initial assortment rather than to convergence of phenotypes. With data from three well-known longitudinal studies, phenotypic convergence is examined using both variable- and person-centered analyses. The longitudinal evidence does not support the hypothesis that couples increasingly resemble each other with time. Spouse correlations most likely reflect initial assortment at marriage and not the convergence of phenotypes.

  4. Poverty and Civil War: Revisiting the Evidence

    OpenAIRE

    Djankov, Simeon; Reynal-Querol, Marta

    2010-01-01

    Previous research has interpreted the correlation between per capita income and civil war as evidence that poverty is a main determinant of conflict. In this paper, we find that the relationship between poverty and civil war is spurious and is accounted for by historical phenomena that jointly determine income evolution and conflict. In particular, the statistical association between poverty and civil wars disappears once we include country fixed effects. Also, using cross-section data for 19...

  5. Standardised Packaging of Tobacco Products Evidence Review

    OpenAIRE

    Department of Health

    2014-01-01

    The current report reviews the scientific evidence on standardised or “plain” packaging, and the extent to which plain packaging regulations would help Ireland to achieve its tobacco control objectives.   Plain packaging is a form of marketing restriction that prohibits the use of logos, colours, brand images and promotional information on tobacco packaging. Under plain packaging regulations, the colour of the pack is uniform across different brands and varieties. Regulations ma...

  6. CAN AYURVEDA BE AN EVIDENCE BASED MEDICINE?

    OpenAIRE

    Bali Yogitha

    2012-01-01

    The concepts of EBM empower us to formulate appropriate clinical questions, appraise the literature using the hierarchy of evidence and apply the study results to their practice. With the ever increasing demands to adopt EBM in practice, healthcare providers require educational resources that present the concepts of the EBM, research methodology and guides to publishing medical research in a simple and easy to understand format. EBM also promotes critical thinking by clinicians. It requires t...

  7. [Acupressure and Evidence-Based Nursing].

    Science.gov (United States)

    Chen, Li-Li; Lin, Jun-Dai

    2015-12-01

    Acupressure is a traditional Chinese medicine approach to disease prevention and treatment that may be operated by nurses independently. Therefore, acupressure is being increasingly applied in clinical nursing practice and research. Recently, the implementation of evidence-based nursing (EBN) in clinical practice has been encouraged to promote nursing quality. Evidence-based nursing is a method-ology and process of implementation that applies the best-available evidence to clinical practice, which is acquired through the use of empirical nursing research. Therefore, in this paper, we address the topic of acupressure within the context of empirical nursing practice. We first introduce the current status of acupressure research and provide the locations of common acupoints in order to guide future empirical nursing research and to help nurses use these acupoints in clinical practice. Finally, we describe the steps that are necessary to apply the current empirical information on acupressure as well as provide suggestions to promote safety and efficacy in order to guide nurses in the accurate application of acupressure in nursing practice. PMID:26645442

  8. Ramadan fasting: Do we need more evidence?

    Directory of Open Access Journals (Sweden)

    Mohsen Nematy

    2015-03-01

    Full Text Available Over a billion of Muslims fast worldwide during Ramadan each year. Through this religious custom, fasting contributes to their health as well as their spiritual growth. However, available evidence regarding the health-benefits of Ramadan fasting is scarce and highly contentious. Although Islam exempts patients from fasting, many fast conceivably, and their clinical condition is prone to deteriorate due to persistent gap between current expert knowledge and conclusive strong evidence regarding the pathophysiologic and metabolic alterations of fasting and the consensus that should be taken into account to implements guided managing of various patient groups during Ramadan fasting among health care professionals. In this article, we summarized the results of initial studies regarding the effects of Ramadan fasting on some clinical conditions including alterations of body composition and clinically important outcomes of patients with a previous history of cardiovascular disease, asthma and renal colic disease. Our studies have shed light on several outcomes in favor of Ramadan fasting, and encourage those with mentioned diseases to consult their physicians and follow medical and scientific recommendations. In this review we aimed to present a piece of relevant evidence, clarify future scope and provide suggestions for future investigations.

  9. Evidence based psychosocial interventions in substance use

    Directory of Open Access Journals (Sweden)

    Sonali Jhanjee

    2014-01-01

    Full Text Available In recent years, there has been significant progress and expansion in the development of evidence-based psychosocial treatments for substance abuse and dependence. A literature review was undertaken using the several electronic databases (PubMed, Cochrane Database of systemic reviews and specific journals, which pertain to psychosocial issues in addictive disorders and guidelines on this topic. Overall psychosocial interventions have been found to be effective. Some interventions, such as cognitive behavior therapy, motivational interviewing and relapse prevention, appear to be effective across many drugs of abuse. Psychological treatment is more effective when prescribed with substitute prescribing than when medication or psychological treatment is used alone, particularly for opiate users. The evidence base for psychological treatment needs to be expanded and should also include research on optimal combinations of psychological therapies and any particular matching effects, if any. Psychological interventions are an essential part of the treatment regimen and efforts should be made to integrate evidence-based interventions in all substance use disorder treatment programs.

  10. Common pitfalls in statistical analysis: "No evidence of effect" versus "evidence of no effect"

    Directory of Open Access Journals (Sweden)

    Priya Ranganathan

    2015-01-01

    Full Text Available This article is the first in a series exploring common pitfalls in statistical analysis in biomedical research. The power of a clinical trial is the ability to find a difference between treatments, where such a difference exists. At the end of the study, the lack of difference between treatments does not mean that the treatments can be considered equivalent. The distinction between "no evidence of effect" and "evidence of no effect" needs to be understood.

  11. Ambulance officers' use of online clinical evidence

    Directory of Open Access Journals (Sweden)

    Westbrook Mary T

    2006-07-01

    Full Text Available Abstract Background Hospital-based clinicians have been shown to use and attain benefits from online evidence systems. To our knowledge there have been no studies investigating whether and how ambulance officers use online evidence systems if provided. We surveyed ambulance officers to examine their knowledge and use of the Clinical Information Access Program (CIAP, an online evidence system providing 24-hour access to information to support evidence-based practice. Methods A questionnaire was completed by 278 ambulance officers in New South Wales, Australia. Comparisons were made between those who used CIAP and officers who had heard of, but not used CIAP. Results Half the sample (48.6% knew of, and 28.8% had used CIAP. Users were more likely to have heard of CIAP from a CIAP representative/presentation, non-users from written information. Compared to ambulance officers who had heard of but had not used CIAP, users were more likely to report better computer skills and that their supervisors regarded use of CIAP as a legitimate part of ambulance officers' clinical role. The main reasons for non-use were lack of access(49.0% and training(31.4%. Of users, 51.3% rated their skills at finding information as good/very good, 67.5% found the information sought all/most of the time, 87.3% believed CIAP had the potential to improve patient care and 28.2% had directly experienced this. Most access to CIAP occurred at home. The databases frequently accessed were MIMS (A medicines information database (73.8% and MEDLINE(67.5%. The major journals accessed were Journal of Emergency Nursing(37.5%, American Journal of Medicine(30.0% and JAMA(27.5%. Conclusion Over half of ambulance officers had not heard of CIAP. The proportion who knew about and used CIAP was also low. Reasons for this appear to be a work culture not convinced of CIAP's relevance to pre-hospital patient care and lack of access to CIAP at work. Ambulance officers who used CIAP accessed it

  12. When Evidence Doesn’t Work (Editorial

    Directory of Open Access Journals (Sweden)

    Lindsay Glynn

    2007-12-01

    Full Text Available I was listening intently to a discussion on the radio recently between Newfoundland and Labrador’s Minister of Education and aprofessor from Memorial University’s Math Department. They were debating the efficacy of the math curriculum in the province’s school system. As a parent of a grade 3 student, I have my own thoughts on how the curriculum is affecting kids’ math skills (and their anxiety levels, but let’s not go there. The professor echoed the concern that parents, teachers and students have been expressing: quite simply, it’s not working. Far too many children are failing math and are struggling with the both the content and pace of the required modules. Why am I telling you this? One particular comment made by the Minister of Education struck me. She said that there was evidence to suggest that this curriculum should work. While I’m always delighted to see the evidence based practice model being used, particularly for the betterment of my kids’education, it is dismaying to see that it is not always applied well. In this particular case, evidence was collected from somewhere and a decision was made to implement a new math curriculum based on the gathered evidence. Assuming that this truly was good evidence upon which to base such a decision, then I would have to concede that the appropriate steps were taken up until that point. Unfortunately, it appears that the entire process stopped there. As we know, one of the most important components of a thorough ebp‐based implementation is an internal evaluation. What might work somewhere else is not guaranteed to work in another environment, and it is essential to determine why an implementation or intervention worked or didn’t work. It would seem, in this case, that formal evaluations of the effectiveness of the new math curriculum have not been performed and therefore, the powers that be rely solely on the fact that it worked somewhere else. This is not evidence based

  13. "Evidence" Under a Magnifying Glass: Thoughts on Safety Argument Epistemology

    Science.gov (United States)

    Graydon, P. J.; Holloway, C. M.

    2015-01-01

    Common definitions of "safety case" emphasize that evidence is the basis of a safety argument, yet few widely referenced works explicitly define "evidence". Their examples suggest that similar things can be regarded as evidence. But the category evidence seems to contain (1) processes for finding things out, (2) information resulting from such processes, and (3) relevant documents. Moreover, any item of evidence could be replaced by further argument. Normative models of informal argumentation do not offer clear guidance on when a safety argument should cite evidence rather than appeal to a more detailed argument. Disciplines such as the law address the problem with a practical, domain-specific epistemology. In this paper, we explore these problems associated with evidence citations in safety arguments, identify goals for a theory of safety argument evidence and a practical safety argument epistemology, propose a model of safety evidence citation that advances the identified goals, and present a related extension to the Goal Structuring Notation (GSN).

  14. Teaching strategies to support evidence-based practice.

    Science.gov (United States)

    Winters, Charlene A; Echeverri, Rebecca

    2012-06-01

    Evidence-based practice is an expected core competency of all health care clinicians regardless of discipline. Use of evidence-based practice means integrating the best research with clinical expertise and patient values to achieve optimal health outcomes. Evidence-based practice requires nurses to access and appraise evidence rapidly before integrating it into clinical practice. Role modeling and integrating the skills necessary to develop evidence-based practice into clinical and nonclinical courses is an important part in developing positive attitudes toward evidence-based practice, an essential first step to using evidence to guide practice decisions. The step-by-step approach to evidence-based practice proposed by Melnyk and colleagues provides an excellent organizing framework for teaching strategies specifically designed to facilitate nurses' knowledge and skill development in evidence-based practice.

  15. Uma visão evidente da prática baseada em evidências na medicina perinatal: ausência de evidência não é evidência de ausência An evident view of evidence-based pratice in perinatal medicine: absence of evidence is not evidence of absence

    Directory of Open Access Journals (Sweden)

    Augusto Sola

    2007-10-01

    Full Text Available OBJETIVO: Proporcionar elementos valiosos e um pouco de humor nesta chamada era da "prática baseada em evidências" com o objetivo de ajudar os clínicos a fazer escolhas melhores no cuidado que eles provêem com base em evidências, e não simples ou exclusivamente com base em um ensaio clínico randomizado (ECR ou meta-análise (o que pode não ser evidência. FONTE DOS DADOS: Livros e artigos com revisão por pares são citados e listados na bibliografia. Evidências de vida, aprendizado através de nossos próprios erros e muitos outros fatos evidentes que sustentam esta revisão não são citados. SÍNTESE DOS DADOS: 1 "Ausência de evidência não é evidência de ausência" e "falta de evidência de efeito não significa evidência de nenhum efeito". 2 Os ECR com resultado "negativo" e aqueles com resultado "positivo", mas sem os resultados importantes, muitas vezes não podem concluir o que concluem. 3 Os ensaios clínicos não-randomizados e os estudos práticos podem ser importantes. 4 A pesquisa em busca de provas é diferente da pesquisa em busca de aperfeiçoamento. 5 A escolha clínica deve avaliar os efeitos nos desfechos importantes para os pacientes e seus pais. 6 A quantificação de desfechos adversos, do número necessário para causar dano e do número necessário para tratamento não é assim tão simples. CONCLUSÕES: Desafios importantes inerentes à pesquisa em serviços de saúde devem ser correlacionados a possíveis aplicações clínicas usando ferramentas que permitam uma "visão mais clara da prática baseada em evidências" na medicina perinatal, lembrando que a ausência de evidência não é evidência de ausência.OBJECTIVE: To provide valuable elements and some humor in this so-called era of "evidence-based practice" with the aim of helping clinicians make better choices in the care they deliver based on evidence, not simply or exclusively based on a randomized clinical trial (RCT or meta-analysis (which may

  16. Health systems integration: state of the evidence

    Directory of Open Access Journals (Sweden)

    Gail D. Armitage

    2009-06-01

    Full Text Available Introduction: Integrated health systems are considered a solution to the challenge of maintaining the accessibility and integrity of healthcare in numerous jurisdictions worldwide. However, decision makers in a Canadian health region indicated they were challenged to find evidence-based information to assist with the planning and implementation of integrated healthcare systems. Methods: A systematic literature review of peer-reviewed literature from health sciences and business databases, and targeted grey literature sources. Results: Despite the large number of articles discussing integration, significant gaps in the research literature exist. There was a lack of high quality, empirical studies providing evidence on how health systems can improve service delivery and population health. No universal definition or concept of integration was found and multiple integration models from both the healthcare and business literature were proposed in the literature. The review also revealed a lack of standardized, validated tools that have been systematically used to evaluate integration outcomes. This makes measuring and comparing the impact of integration on system, provider and patient level challenging. Discussion and conclusion: Healthcare is likely too complex for a one-size-fits-all integration solution. It is important for decision makers and planners to choose a set of complementary models, structures and processes to create an integrated health system that fits the needs of the population across the continuum of care. However, in order to have evidence available, decision makers and planners should include evaluation for accountability purposes and to ensure a better understanding of the effectiveness and impact of health systems integration.

  17. How to synthesize evidence for imaging guidelines

    Energy Technology Data Exchange (ETDEWEB)

    Matowe, L. E-mail: l.matowe@hsc.kuniv.edu.kw; Gilbert, F. J

    2004-01-01

    AIM: To provide guidance on how to gather and evaluate evidence from the literature on the efficacy of imaging, using as an example the assessment of the role of magnetic resonance imaging (MRI) in the diagnosis of osteomyelitis. This method was adopted for evaluating evidence for the musculoskeletal section of the 5th edition of the Royal College of Radiologists' (RCR) guidelines. MATERIALS AND METHODS: A systematic review of the literature published between 1966 and July 2001 was carried out. Eligible articles described studies in patients with suspected osteomyelitis and who were diagnosed using MRI. Search strategies were developed to identify relevant imaging studies. Studies included in the systematic review were selected using predefined criteria. The sensitivity, specificity, accuracy and likelihood ratios for MRI reported in the studies were used to evaluate the value of the procedure in osteomyelitis. Where the above were not reported, they were calculated by the reviewers. RESULTS: The average sensitivity of MRI in osteomyelitis was 91% (range 76-100%), the average specificity was 82% (range 65-96%), average accuracy was 88% (range 71-97%), and the average positive likelihood ratio was 7.8 (range 2.3-21.1). Four studies evaluated the use of MRI in the diagnosis of osteomyelitis in the diabetic foot, two in osteomyelitis of the lower extremities, while four each evaluated the use of MRI in vertebral osteomyelitis, in the diagnosis of any form of osteomyelitis, osteomyelitis in spinal cord-injured patients and in cranial osteomyelitis. CONCLUSION: Systematic reviews of literature can be used to obtain evidence on the value of imaging procedures. The quality of the studies included in the review should always be considered when selecting studies to limit bias. In our example, MRI appears sensitive, specific and accurate in the diagnosis of osteomyelitis at different sites.

  18. Negative evidence in L2 acquisition

    Directory of Open Access Journals (Sweden)

    Anne Dahl

    2005-02-01

    Full Text Available This article deals with the L2 acquisition of differences between Norwegian and English passives, and presents data to show that the acquisition of these differences by Norwegian L2 acquirers of English cannot be fully explained by positive evidence, cues, conservativism or economy. Rather, it is argued, it is natural to consider whether indirect negative evidence may facilitate acquisition by inferencing. The structures in focus are impersonal passive constructions with postverbal NPs and passive constructions with intransitive verbs. These sentences are ungrammatical in English. Chomsky (1981 proposes that this is a result of passive morphology absorbing objective case in English. There is no such case to be assigned to the postverbal NP in impersonal passives. In passive constructions with intransitive verbs, the verb does not assign objective case, so that there is no case for the passive morphology to absorb. Thus, impersonal passives have to be changed into personal passives, where the NP receives nominative case, and the objective case is free to go to the passive morphology. Intransitive verbs, however, cannot be used in the passive voice at all. Both the structures discussed in this article, i.e. are grammatical in Norwegian. However, the options available in English, viz. personal passives and active sentences, are equally possible. Åfarli (1992 therefore proposes that Norwegian has optional case absorption (passive morphology optionally absorbs case. On the basis on such observations, we may propose a parameter with the settings [+case absorption] for English, and [-case absorption], signifying optional case absorption, for Norwegian. This means that none of the structures that are grammatical in English can function as positive evidence for the [+case absorption] setting, since they are also grammatical in optional case absorption languages. The question is how this parameter is set.

  19. Evidence for indications of fresh frozen plasma.

    Science.gov (United States)

    Stanworth, S J; Hyde, C J; Murphy, M F

    2007-12-01

    There continues to be a general but unfounded enthusiasm for fresh frozen plasma (FFP) usage across a range of clinical specialties in hospital practice. Clinical use of plasma has grown steadily over the last two decades in many countries. In England and Wales, there has not been a significant reduction in the use of FFP over the last few years, unlike red cells. There is also evidence of variation in usage among countries--use in England and Wales may be proportionately less per patient than current levels of usage in other European countries and the United States. Plasma for transfusion is most often used where there is abnormal coagulation screening tests, either therapeutically in the face of bleeding, or prophylactically in non-bleeding subjects prior to invasive procedures or surgery. Little evidence exists to inform best therapeutic plasma transfusion practice. Most studies have described plasma use in a prophylactic setting, in which laboratory abnormalities of coagulation tests are considered a predictive risk factor for bleeding prior to invasive procedures. The strongest randomised controlled trial (RCT) evidence indicates that prophylactic plasma for transfusion is not effective across a range of different clinical settings and this is supported by data from non-randomised studies in patients with mild to moderate abnormalities in coagulation tests. There are also uncertainties whether plasma consistently improves the laboratory results for patients with mild to moderate abnormalities in coagulation tests. There is a need to undertake new trials evaluating the efficacy and adverse effects of plasma, both in bleeding and non-bleeding patients, to understand whether the "presumed" benefits outweigh the "real risks". In addition, new haemostatic tests should be validated which better define risk of bleeding.

  20. Evidences for magicity in superdeformed shapes

    Indian Academy of Sciences (India)

    Suresh Kumar

    2014-05-01

    Many empirical evidences that point to the existence of preferred magic nucleon numbers for superdeformed (SD) shapes are presented in this paper. We use a simple premise based on the 4-parameter formula fitted using observed -rays of SD bands. In particular, plots of -ray energy ratios, nuclear softness parameter values and the number of SD bands for given and are used to pinpoint the magicity (, numbers) that are most favoured as the SD magic numbers. This analysis also leads to several new predictions on the occurrence of SD bands specially in neutron-rich nuclei.

  1. Direct Evidence on Learning by Exporting

    DEFF Research Database (Denmark)

    Grimpe, Christoph; Belderbos, Rene

    2014-01-01

    We examine first direct evidence on the occurrence of learning by exporting, using unique survey data for German innovating firms on the role of (foreign) customers and competitors as sources of ideas and impetus for innovation. Export intensive firms frequently benefit simultaneously from domestic...... learning and innovativeness. Firms adopting a strategy of technology leadership more often exhibit effective learning from diverse foreign customers and this learning is strongly associated with innovative sales – but mostly so if combined with domestic customer learning. In contrast, firms that have...... not adopted a leadership strategy benefit most from foreign competitor learning, as they are more likely to respond to competitive pressures abroad by product imitation....

  2. Evidence for weight effects in Russian

    DEFF Research Database (Denmark)

    Kizach, Johannes

    2012-01-01

    It is well-known that factors such as weight, pronominality, animacy and newness influence word order in several languages, but whereas newness repeatedly has been argued to be a relevant factor for Russian, little or no attention has been paid to weight. In this paper, which is based on evidence...... from corpus data, weight is demonstrated to have a very significant influence on word order in Russian. Specifically, four constructions are tested: Postverbal PPs, the double object construction, adversity impersonals and the order of S, V and O. In all cases the same pattern emerges: The heavier...

  3. The religion of evidence-based practice

    DEFF Research Database (Denmark)

    Wigram, Tony; Gold, Christian

    2012-01-01

    , and discusses autism spectrum disorders and EBP. The chapter concludes that, based on last sixty years of the development of music therapy as a recognized and relevant intervention, there is no doubt that the honeymoon period is over, and EBP is here to stay. Despite examples of attrition in music therapy...... practice as health, education, and social services tighten their belts and the demand on their resources grows, there is increasing interest in the value of music for health and wellbeing, despite even less ‘hard’ evidence that it is effective against illness and disability....

  4. Parliamentary select committees: who gives evidence?

    OpenAIRE

    Berry, Richard; Kippin, Sean

    2014-01-01

    Parliamentary select committees are an increasingly important part of the democratic process in the UK. Their impact has grown in recent years, as has their media profile. The latter is partly due to the appearance of high-profile witnesses as committee hearings. The calling of witnesses is, in fact, a vital part of a select committee’s role, as it allows MPs and peers to hold government ministers and officials to account, as well as gather evidence from experts and stakeholders outside gover...

  5. Evidence for further charmonium vector resonances

    Institute of Scientific and Technical Information of China (English)

    Eel van Bevere; George Rupp

    2011-01-01

    We discuss the shape of threshold signals in production cross sections of the reaction e+e- → D* Dˉ*, at the opening of the Ds* Dˉs* and Λc+ Λ+c channels. Furthermore, evidence for the ψ(3D), ψ(5S), ψ(4D), ψ(6S), ψ(5D), ψ(7S), ψ(6D), and ψ(8S) new charmon

  6. Astrophysical Black Holes: Evidence of a Horizon?

    Science.gov (United States)

    Colpi, Monica

    In this Lecture Note we first follow a short account of the history of the black hole hypothesis. We then review on the current status of the search for astrophysical black holes with particular attention to the black holes of stellar origin. Later, we highlight a series of observations that reveal the albeit indirect presence of supermassive black holes in galactic nuclei, with mention to forthcoming experiments aimed at testing directly the black hole hypothesis. We further focus on evidences of a black hole event horizon in cosmic sources.

  7. Palaeoclimatology: evidence for hot early oceans?

    Science.gov (United States)

    Shields, Graham A; Kasting, James F

    2007-05-01

    The oxygen isotopes in sedimentary cherts (siliceous sediments) have been used to argue that the Precambrian oceans were hot--with temperatures of up to 70 degrees C at 3.3 Gyr before present. Robert and Chaussidon measure silicon isotopes in cherts and arrive at a similar conclusion. We suggest here that both isotope trends may be caused by variations in seawater isotope composition, rather than in ocean temperatures. If so, then the climate of the early Earth may have been temperate, as it is today, and therefore more consistent with evidence for Precambrian glaciations and with constraints inferred from biological evolution.

  8. SMARANDACHE HYPOTHESIS: EVIDENCES, IMPLICATIONS AND APPLICATIONS

    OpenAIRE

    Motta, Leonardo

    2000-01-01

    In 1972, Smarandache proposed that there is not a limit speed on the nature, based on the EPR-Bell (Einstein, Podolsky, Rosen, Bell) paradox. Although it appears that this paradox was solved recently, there are many other evidences that guide us to believe that Smarandache Hypothesis is right on quantum mechanics and even on the new unification theories. If Smarandache Hypothesis turns to be right under any circumstance, some concepts of modern physics would have to be ...

  9. Expert scientific evidence in the Israeli court.

    Science.gov (United States)

    Sahar, A

    2007-06-01

    Most judges, by the very nature of their educational background, are less than sufficiently prepared for the task to fully comprehend the problems in disputes concerning scientific subjects. Judicial cognizance in such matters gives no support. The judge has no recourse but to rely on Expert Evidence. However, such evidence, especially in the adversarial system, requires the ability to evaluate it. Back to square one? Almost. The Israeli court borrowed, and followed for many years, the American solution - the Frye Principle (Frye v. United States, 54 App.D.C. at 47, 293 F. 1013 (1923) 1014) - "the thing from which the deduction is made must be sufficiently established to have gained general acceptance in the particular field in which it belongs " - meaning that an Expert's view is held as true if proven that it had been held by "the scientific community." This solution presented an almost insurmountable problem for novel scientific ideas. The were also exceptions - several Israeli Courts made the rather difficult task of examining the Experts' "working papers", i.e. the "crude" data on which he based his deductions. The model of such effort seems to be the English decision, by Stuart-Smith LJ in Loveday v Renton and Wellcome Foundation Ltd. ( (QBD) 1 Med Law Review, 1990:117). Seventy years after Frye the U.S. Supreme Court reviewed the subject of evaluation of scientific evidence. The new requirements were "... (1) ... whether the theory or technique can be and has been tested; (2) ... whether the theory or technique has been subjected to peer review ... (3) ... the known or potential rate of error of[the] technique; (4) [no requirement of] a particular degree of acceptance of the theory or technique within that [scientific] community, ... and (5) the inquiry is a flexible one, and the focus must be solely on principles and methodology, not on the conclusions that such principles and methodology generate ". Namely - the Judge, guided by intelligence and logic, is

  10. Do Poverty Traps Exist? Assessing the Evidence

    OpenAIRE

    Kraay, Aart; McKenzie, David

    2014-01-01

    A "poverty trap" can be understood as a set of self-reinforcing mechanisms whereby countries start poor and remain poor: poverty begets poverty, so that current poverty is itself a direct cause of poverty in the future. The idea of a poverty trap has this striking implication for policy: much poverty is needless, in the sense that a different equilibrium is possible and one-time policy efforts to break the poverty trap may have lasting effects. But what does the modern evidence suggest about ...

  11. Primordial Features as Evidence for Inflation

    CERN Document Server

    Chen, Xingang

    2011-01-01

    In the primordial universe, particles with mass much larger than the mass-scale of the event-horizon (such as the Hubble parameter in inflation) exist ubiquitously, and can be excited from time to time and oscillate quickly around its minimum. These excitations can induce specific patterns in density perturbations, which record the time dependence of the scale factor of the primordial universe, thus provide direct evidence for the inflationary epoch or its alternatives. Such effects are conventionally integrated out in theoretical and data analyses, but can be accessible for experiments targeting on density perturbations with high multiples.

  12. Unhappiness and Crime: Evidence from South Africa

    OpenAIRE

    Nattavudh Powdthavee

    2003-01-01

    This paper is the first of its kind to study quality of life responses of crime victims. Using cross-sectional data from the OHS97 survey of South Africa, we show that victims report significantly lower well-being than the non-victims, ceteris paribus. Happiness is lower for nonvictimized respondents currently living in higher crime areas. However, we find a strong evidence for females that criminal victimization hurts, but hurts less if the crime rate on our reference group is high.

  13. Evidence, discovery and justification: the case of evidence-based medicine.

    Science.gov (United States)

    Gaeta, Rodolfo; Gentile, Nelida

    2016-08-01

    The purpose of this paper is to develop some thoughts on philosophical issues surrounding evidence-based medicine (EBM), especially related to its epistemological dimensions. After considering the scope of several philosophical concepts that are relevant to the discussion, and drawing some distinctions among different aspects of EBM, we evaluate the status of EBM and suggest that EBM is mainly a meta-methodology. Then, we outline an evaluation of the thesis that EBM is a 'new paradigm' in the practice of medicine. We argue that EBM does not seem to have arisen in the way Kuhn imagined paradigms to arise but as a conscious, deliberate proposal, more as programme than as a reality. Furthermore, there is something paradoxical about appealing to evidence or to the best evidence as a way of promoting a new paradigm. For the proposal seems to assume that there is something that by its own virtue is the best evidence for a given time. But this idea would have been rejected by Kuhn. If EBM involves a genuine new alternative in the field of medicine and shows a way in which the discipline will endure henceforth, this indicates that it is not what Kuhn once called a 'paradigm' and even, paradoxically, it is good evidence that scientific paradigms do not exist, at least in medicine. PMID:26200433

  14. How to understand and conduct evidence-based medicine

    Science.gov (United States)

    2016-01-01

    Evidence-based medicine (EBM) is the conscientious, explicit, and judicious use of current best evidence in making decisions regarding the care of individual patients. This concept has gained popularity recently, and its applications have been steadily expanding. Nowadays, the term "evidence-based" is used in numerous situations and conditions, such as evidence-based medicine, evidence-based practice, evidence-based health care, evidence-based social work, evidence-based policy, and evidence-based education. However, many anesthesiologists and their colleagues have not previously been accustomed to utilizing EBM, and they have experienced difficulty in understanding and applying the techniques of EBM to their practice. In this article, the author discusses the brief history, definition, methods, and limitations of EBM. As EBM also involves making use of the best available information to answer questions in clinical practice, the author emphasizes the process of performing evidence-based medicine: generate the clinical question, find the best evidence, perform critical appraisal, apply the evidence, and then evaluate. Levels of evidence and strength of recommendation were also explained. The author expects that this article may be of assistance to readers in understanding, conducting, and evaluating EBM.

  15. Adopting Hadith Verification Techniques in to Digital Evidence Authentication

    Directory of Open Access Journals (Sweden)

    Yunus Yusoff

    2010-01-01

    Full Text Available Problem statement: The needs of computer forensics investigators have been directly influenced by the increasing number of crimes performed using computers. It is the responsibility of the investigator to ascertain the authenticity of the collected digital evidence. Without proper classification of digital evidence, the computer forensics investigator may ended up investigating using untrusted digital evidence and ultimately cannot be use to implicate the suspected criminal. Approach: The historical methods of verifying the authenticity of a hadith were studied. The similarities between hadith authentication and digital evidence authentication were identified. Based on the similarities of the identified processes, a new method of authenticating digital evidence were proposed, together with the trust calculation algorithm and evidence classification. Results: The new investigation processes and an algorithm to calculate the trust value of a given digital evidence was proposed. Furthermore, a simple classification of evidence, based on the calculated trust values was also proposed. Conclusion/Recommendations: We had successfully extracted the methods to authenticate hadith and mapped it into the digital evidence authentication processes. The trust values of digital evidence were able to be calculated and the evidence can be further classified based on the different level of trust values. The ability to classify evidence based on trust levels can offer great assistance to the computer forensics investigator to plan their works and focus on the evidence that would give them a better chance of catching the criminals.

  16. Brain and language: evidence for neural multifunctionality.

    Science.gov (United States)

    Cahana-Amitay, Dalia; Albert, Martin L

    2014-01-01

    This review paper presents converging evidence from studies of brain damage and longitudinal studies of language in aging which supports the following thesis: the neural basis of language can best be understood by the concept of neural multifunctionality. In this paper the term "neural multifunctionality" refers to incorporation of nonlinguistic functions into language models of the intact brain, reflecting a multifunctional perspective whereby a constant and dynamic interaction exists among neural networks subserving cognitive, affective, and praxic functions with neural networks specialized for lexical retrieval, sentence comprehension, and discourse processing, giving rise to language as we know it. By way of example, we consider effects of executive system functions on aspects of semantic processing among persons with and without aphasia, as well as the interaction of executive and language functions among older adults. We conclude by indicating how this multifunctional view of brain-language relations extends to the realm of language recovery from aphasia, where evidence of the influence of nonlinguistic factors on the reshaping of neural circuitry for aphasia rehabilitation is clearly emerging.

  17. Inhaled corticosteroids in COPD: the clinical evidence.

    Science.gov (United States)

    Ernst, Pierre; Saad, Nathalie; Suissa, Samy

    2015-02-01

    In this article, we focus on the scientific evidence from randomised trials supporting treatment with inhaled corticosteroids (ICS) in chronic obstructive pulmonary disease (COPD), including treatment with combinations of long-acting β-agonist (LABA) bronchodilators and ICS. Our emphasis is on the methodological strengths and limitations that guide the conclusions that may be drawn. The evidence of benefit of ICS and, therefore, of the LABA/ICS combinations in COPD is limited by major methodological problems. From the data reviewed herein, we conclude that there is no survival benefit independent of the effect of long-acting bronchodilation and no effect on FEV1 decline, and that the possible benefit on reducing severe exacerbations is unclear. Our interpretation of the data is that there are substantial adverse effects from the use of ICS in patients with COPD, most notably severe pneumonia resulting in excess deaths. Currently, the most reliable predictor of response to ICS in COPD is the presence of eosinophilic inflammation in the sputum. There is an urgent need for better markers of benefit and risk that can be tested in randomised trials for use in routine specialist practice. Given the overall safety and effectiveness of long-acting bronchodilators in subjects without an asthma component to their COPD, we believe use of such agents without an associated ICS should be favoured. PMID:25537556

  18. Access with evidence development: the US experience.

    Science.gov (United States)

    Mohr, Penny E; Tunis, Sean R

    2010-01-01

    The concept of access with evidence development (AED), also known as 'coverage with evidence development' in the Medicare programme, has long been discussed as a policy option for ensuring more appropriate use of new technologies in the US. This article provides a comprehensive overview of more than 10 years of US experience with AED, both in the public and private healthcare sectors. Beginning with a discussion of the successes of private plans' conditional coverage for high-density chemotherapy for autologous bone marrow transplants for metastatic breast cancer and Medicare's conditional coverage of lung-volume-reduction surgery in the 1990s, the article moves on to describe how Medicare worked to codify AED as one of its coverage policy options in the early part of this decade. More recent private and public sector initiatives are also discussed, including an overview of barriers to implementing AED. Despite the complexity of political, financial and ethical issues faced in implementation, AED is now a permanent fixture of US coverage policy. Future initiatives within the Medicare programme and with private payers in the US are much more likely to succeed by relying upon the simple but consequential principles laid out at a Summit convened in Banff, Alberta, Canada in 2009 and presented in another article in this issue. PMID:20085391

  19. Infection and childhood leukemia: review of evidence

    Directory of Open Access Journals (Sweden)

    Raquel da Rocha Paiva Maia

    2013-12-01

    Full Text Available OBJECTIVE : To analyze studies that evaluated the role of infections as well as indirect measures of exposure to infection in the risk of childhood leukemia, particularly acute lymphoblastic leukemia. METHODS : A search in Medline, Lilacs, and SciELO scientific publication databases initially using the descriptors “childhood leukemia” and “infection” and later searching for the words “childhood leukemia” and “maternal infection or disease” or “breastfeeding” or “daycare attendance” or “vaccination” resulted in 62 publications that met the following inclusion criteria: subject aged ≤ 15 years; specific analysis of cases diagnosed with acute lymphoblastic leukemia or total leukemia; exposure assessment of mothers’ or infants’ to infections (or proxy of infection, and risk of leukemia. RESULTS : Overall, 23 studies that assessed infections in children support the hypothesis that occurrence of infection during early childhood reduces the risk of leukemia, but there are disagreements within and between studies. The evaluation of exposure to infection by indirect measures showed evidence of reduced risk of leukemia associated mainly with daycare attendance. More than 50.0% of the 16 studies that assessed maternal exposure to infection observed increased risk of leukemia associated with episodes of influenza, pneumonia, chickenpox, herpes zoster, lower genital tract infection, skin disease, sexually transmitted diseases, Epstein-Barr virus, and Helicobacter pylori . CONCLUSIONS : Although no specific infectious agent has been identified, scientific evidence suggests that exposure to infections has some effect on childhood leukemia etiology.

  20. Body selectivity in occipitotemporal cortex: Causal evidence.

    Science.gov (United States)

    Downing, Paul E; Peelen, Marius V

    2016-03-01

    Perception of others' bodies provides information that is useful for a number of important social-cognitive processes. Evidence from neuroimaging methods has identified focal cortical regions that are highly selective for perceiving bodies and body parts, including the extrastriate body area (EBA) and fusiform body area (FBA). Our understanding of the functional properties of these regions, and their causal contributions to behavior, has benefitted from the study of neuropsychological patients and particularly from investigations using transcranial magnetic stimulation (TMS). We review this evidence, focusing on TMS studies that are revealing of how (and when) activity in EBA contributes to detecting people in natural scenes; to resolving their body shape, movements, actions, individual parts, and identities; and to guiding goal-directed behavior. These findings are considered in reference to a framework for body perception in which the patterns of neural activity in EBA and FBA jointly serve to make explicit the elements of the visual scene that correspond to the body and its parts. These representations are modulated by other sources of information such as prior knowledge, and are shared with wider brain networks involved in many aspects of social cognition. PMID:26044771

  1. Nutrition and Dementia: Evidence for Preventive Approaches?

    Science.gov (United States)

    Canevelli, Marco; Lucchini, Flaminia; Quarata, Federica; Bruno, Giuseppe; Cesari, Matteo

    2016-01-01

    In recent years, the possibility of favorably influencing the cognitive trajectory through promotion of lifestyle modifications has been increasingly investigated. In particular, the relationship between nutritional habits and cognitive health has attracted special attention. The present review is designed to retrieve and discuss recent evidence (published over the last 3 years) coming from randomized controlled trials (RCTs) investigating the efficacy of nutritional interventions aimed at improving cognitive functioning and/or preventing cognitive decline in non-demented older individuals. A systematic review of literature was conducted, leading to the identification of 11 studies of interest. Overall, most of the nutritional interventions tested by the selected RCTs were found to produce statistically significant cognitive benefits (defined as improved neuropsychological test scores). Nevertheless, the clinical meaningfulness of such findings was not adequately discussed and appears controversial. In parallel, only 2 studies investigated between-group differences concerning incident dementia and mild cognitive impairment cases, reporting conflicting results. Results of the present review suggest that several dietary patterns and nutritional components may constitute promising strategies in postponing, slowing, and preventing cognitive decline. However, supporting evidence is overall weak and further studies are needed. PMID:26959055

  2. Disseminating evidence-based care into practice.

    Science.gov (United States)

    Coleman, Eric A; Rosenbek, Susan A; Roman, Sarah P

    2013-08-01

    The Centers for Medicare and Medicaid Services (CMS) has launched the Partnership for Patients initiative, promising a 20% reduction in readmissions nationally across all payers by December 31, 2013. To address this ambitious goal, CMS has awarded grants to Hospital Engagement Networks, Pioneer Accountable Care Organizations, and the Community-based Care Transitions Program, as well as instituted new penalties for excessive readmission that began in October 2012. National efforts aimed at realizing this goal are predicated, in part, on our effectiveness in disseminating evidence-based care models into practice to improve outcomes and reduce costs. The Care Transitions Intervention (CTI) has been developed, tested, and disseminated to over 750 health care organizations in 40 states nationwide. Four factors promote wide-scale CTI dissemination. The first factor focuses on model fidelity whereby adopters are given insight into which elements of the intervention can be adapted and customized. The second factor concerns the selection of Transitions Coaches and reinforcement of their role through training and participation in a national peer learning network. The third factor relates to model execution with attention to integrating the intervention into existing workflows and fostering relationships with community stakeholders. The fourth factor involves cultivating the support to sustain or expand the intervention through continually making the business case in a changing health care landscape. The lessons learned through the dissemination and implementation of the CTI may be generalizable to the spread of a variety of evidence-based care models.

  3. Barriers to Research and Evidence (Editorial

    Directory of Open Access Journals (Sweden)

    Alison Brettle

    2013-06-01

    Full Text Available I often find attending conferences or workshops a source of reflection or inspiration for editorials, and today I attended an event that proved to be no exception. The HEALER network is a UK grouping of professionals interested in health library research. It brings together those working in health information at an academic, practitioner or strategic capacity as well as those working in higher education, research and the NHS. (http://www.libraryservices.nhs.uk/healer/minutes.htmlThere were a number of interesting presentations, but one (and the subsequent interactive discussions left me with some worrying thoughts. Hannah Spring (2013 presented some of the findings from her PhD that found when health librarians were asked about their barriers to research they reported that they didn't know what research questions to ask! Alternatively if they had research questions they didn't think to engage with the literature or believed that there was no evidence to answer them! If we really don't have any research questions, and we really don't think to look at the literature or there really is no evidence, this is worrying indeed for the future of EBLIP. It's also a situation I don't recognize from being involved in the EBLIP journal and was left wondering whether it was the health librarians perceptions of “research” and “evidence” that was the issue; questions which are being examined in the LIRG Scan which was described in another presentation. The scan is a review of the evidence on: What practitioners understand by research; what kind of research is relevant to LIS practitioners? How do they use research and what are the barriers and facilitators to using research in practice? (https://sites.google.com/site/lirgweb/home/awards/lirg-scan-award The results will be used to help inform the Chartered Institute for Library and Information Professionals’ policy on research.The barrier which I’m much more familiar in terms of engaging with

  4. Evidence-Based Interactive Management of Change

    Directory of Open Access Journals (Sweden)

    Albert Fleischmann

    2011-06-01

    Full Text Available Evidence-based interactive management of change means hands-on experience of modified work processes, given evidence of change. For this kind of pro-active organizational development support we use an organisational process memory and a communication-based representation technique for role-specific and task-oriented process execution. Both are effective means for organizations becoming agile through interactively modelling the business at the process level and re-constructing or re-arranging process representations according to various needs. The tool allows experiencing role-specific workflows, as the communication-based refinement of work models allows for executable process specifications. When presenting the interactive processes to individuals involved in the business processes, changes can be explored interactively in a context-sensitive way before re-implementing business processes and information systems. The tool is based on a service-oriented architecture and a flexible representation scheme comprising the exchange of message between actors, business objects and actors (roles. The interactive execution of workflows does not only enable the individual reorganization of work but also changes at the level of the entire organization due to the represented interactions.

  5. The Big Five default brain: functional evidence.

    Science.gov (United States)

    Sampaio, Adriana; Soares, José Miguel; Coutinho, Joana; Sousa, Nuno; Gonçalves, Óscar F

    2014-11-01

    Recent neuroimaging studies have provided evidence that different dimensions of human personality may be associated with specific structural neuroanatomic correlates. Identifying brain correlates of a situation-independent personality structure would require evidence of a stable default mode of brain functioning. In this study, we investigated the correlates of the Big Five personality dimensions (Extraversion, Neuroticism, Openness/Intellect, Agreeableness, and Conscientiousness) and the default mode network (DMN). Forty-nine healthy adults completed the NEO-Five Factor. The results showed that the Extraversion (E) and Agreeableness (A) were positively correlated with activity in the midline core of the DMN, whereas Neuroticism (N), Openness (O), and Conscientiousness (C) were correlated with the parietal cortex system. Activity of the anterior cingulate cortex was positively associated with A and negatively with C. Regions of the parietal lobe were differentially associated with each personality dimension. The present study not only confirms previous functional correlates regarding the Big Five personality dimensions, but it also expands our knowledge showing the association between different personality dimensions and specific patterns of brain activation at rest.

  6. Bipolar disorder: Evidence for a major locus

    Energy Technology Data Exchange (ETDEWEB)

    Spence, M.A.; Flodman, P.L. [Univ. of California, Irvine, CA (United States); Sadovnick, A.D.; Ameli, H. [Univ. of British Columbia, Vancouver (Canada)] [and others

    1995-10-09

    Complex segregation analyses were conducted on families of bipolar I and bipolar II probands to delineate the mode of inheritance. The probands were ascertained from consecutive referrals to the Mood Disorder Service, University Hospital, University of British Columbia and diagnosed by DSM-III-R and Research Diagnostic Criteria. Data were available on over 1,500 first-degree relatives of the 186 Caucasian probands. The purpose of the analyses was to determine if, after correcting for age and birth cohort, there was evidence for a single major locus. Five models were fit to the data using the statistical package SAGE: (1) dominant, (2) recessive, (3) arbitrary mendelian inheritance, (4) environmental, and (5) no major effects. A single dominant, mendelian major locus was the best fitting of these models for the sample of bipolar I and II probands when only bipolar relatives were defined as affected (polygenic inheritance could not be tested). Adding recurrent major depression to the diagnosis {open_quotes}affected{close_quotes} for relatives reduced the evidence for a major locus effect. Our findings support the undertaking of linkage studies and are consistent with the analyses of the National Institutes of Mental Health (NIMH) Collaborative Study data by Rice et al. and Blangero and Elston. 39 refs., 4 tabs.

  7. Nutrition and Dementia: Evidence for Preventive Approaches?

    Directory of Open Access Journals (Sweden)

    Marco Canevelli

    2016-03-01

    Full Text Available In recent years, the possibility of favorably influencing the cognitive trajectory through promotion of lifestyle modifications has been increasingly investigated. In particular, the relationship between nutritional habits and cognitive health has attracted special attention. The present review is designed to retrieve and discuss recent evidence (published over the last 3 years coming from randomized controlled trials (RCTs investigating the efficacy of nutritional interventions aimed at improving cognitive functioning and/or preventing cognitive decline in non-demented older individuals. A systematic review of literature was conducted, leading to the identification of 11 studies of interest. Overall, most of the nutritional interventions tested by the selected RCTs were found to produce statistically significant cognitive benefits (defined as improved neuropsychological test scores. Nevertheless, the clinical meaningfulness of such findings was not adequately discussed and appears controversial. In parallel, only 2 studies investigated between-group differences concerning incident dementia and mild cognitive impairment cases, reporting conflicting results. Results of the present review suggest that several dietary patterns and nutritional components may constitute promising strategies in postponing, slowing, and preventing cognitive decline. However, supporting evidence is overall weak and further studies are needed.

  8. Paleoambientes litorales durante el inicio de la trasgresión marina holocena en bahía Lapataia, canal Beagle, parque nacional Tierra del Fuego Littoral paleoenvironments during the beginning of the Holocene marine transgression in Lapataia Bay, Beagle Channel, National Park of Tierra del Fuego

    Directory of Open Access Journals (Sweden)

    Jorge Rabassa

    2009-12-01

    Full Text Available Los sitios Aserradero Lapataia 1 y 2 presentan depósitos limo-arcillosos portadores de valvas de moluscos: Mulinia edulis, Mytilus chilensis, Aulacomya atra y Yoldia sp. Además predominan los quistes de dinoflagelados, revestimientos de foraminíferos bentónicos y huevos de copépodos. Valvas de Mulinia edulis fueron datadas radiocarbónicamente en 8.094 ± 43 (AA74047 y 8.167 ± 43 (AA74048 a A.P. En Arroyo Baliza depósitos limo-arcillosos son portadores de Venus antiqua, Aulacomya atra, Mytilus chilensis, entre otros. La microflora está dominada por dinoquistes protoperidinioideos, acritarcos y restos de copépodos. Se sugiere ambientes marino-marginales, con baja a moderada salinidad, y altas concentraciones de nutrientes en las aguas superficiales. La datación radiocarbónica sobre Venus antiqua en Arroyo Baliza indica 2.844 ± 34 a A.P. (AA74046. Aserradero Lapataia confirma las edades más antiguas conocidas para la fase estuárica de la transgresión holocena en el canal Beagle. Arroyo Baliza aporta nueva evidencia de la fase regresiva en este canal durante el Holoceno tardío.The Aserradero Lapataia 1 and 2 sites present clayey silty sediments including mollusk shell; Mulinia edulis, Mytilus chilensis, Aulacomya atra and Yoldia sp. Besides, dinoflagelate cysts, covers of benthonic foraminifera and copepod eggs are dominant. The microflora is represented by sporomorphs and fresh to salty water microplancton. Radiocarbon dates on Mulinia edulis shells yielded ages of 8094 ± 43 (AA74047 and 8167 ± 43 (AA74048 yr B.P. At Arroyo Baliza, clayey silts were found including Venus antiqua, Aulacomya atra, Mytilus chilensis, among others, accompanied by acritarchs and remnants of copepods. This association suggests marginal marine environments, with low to moderate salinity, and high nutrient concentration in the surface waters. Radiocarbon dating on Venus antiqua shells yielded 2844 ± 34 yr B.P. (AA74046. Marine deposits of the Aserradero

  9. AN APPROACH FOR EVIDENCE CLUSTERING USING GENERALIZED DISTANCE

    Institute of Scientific and Technical Information of China (English)

    Ye Qing; Wu Xiaoping; Chen Zemao

    2009-01-01

    When evidence comes from multiple events they should be handled independently, and it is unknown to which event a piece of evidence is related. In this paper, the problem of clustering all pieces of evidence is analyzed systematically to separate them into subsets for each event on the basis of considering the describing format of evidence and making full use of the distance of evidence. An approach for evidence clustering using distance of evidence is presented based on the criterion for clustering. In the proposed approach, the method which is used to establish the initialization of clustering is discussed in detail, called an improved optimal distance. And the centroid vector of evidence and the clustering process are developed respectively to obtain the performance of this novel approach. Finally, an illustrative example shows that this approach is feasible and effective.

  10. Incorporating Qualitative Evidence in Systematic Reviews: Strategies and Challenges

    Science.gov (United States)

    Caracelli, Valerie J.; Cooksy, Leslie J.

    2013-01-01

    The quality of mixed methods systematic reviews relies on the quality of primary-level studies. The synthesis of qualitative evidence and the recent development of synthesizing mixed methods studies hold promise, but also pose challenges to evidence synthesis.

  11. Effect of forensic evidence on criminal justice case processing.

    Science.gov (United States)

    Peterson, Joseph L; Hickman, Matthew J; Strom, Kevin J; Johnson, Donald J

    2013-01-01

    This study examined the role and impact of forensic evidence on case-processing outcomes in a sample of 4205 criminal cases drawn from five U.S. jurisdictions. Regression analyses demonstrated that forensic evidence played a consistent and robust role in case-processing decisions. Still, the influence of forensic evidence is time- and examination-dependent: the collection of crime scene evidence was predictive of arrest, and the examination of evidence was predictive of referral for charges, as well as of charges being filed, conviction at trial, and sentence length. The only decision outcome in which forensic evidence did not have a general effect was with regard to guilty plea arrangements. More studies are needed on the filtering of forensic evidence in different crime categories, from the crime scene to its use by investigators, prosecutors, and fact-finders, and to identify factors that shape decisions to collect evidence, submit it to laboratories, and request examinations.

  12. Anomalous Evidence, Confidence Change, and Theory Change.

    Science.gov (United States)

    Hemmerich, Joshua A; Van Voorhis, Kellie; Wiley, Jennifer

    2016-08-01

    A novel experimental paradigm that measured theory change and confidence in participants' theories was used in three experiments to test the effects of anomalous evidence. Experiment 1 varied the amount of anomalous evidence to see if "dose size" made incremental changes in confidence toward theory change. Experiment 2 varied whether anomalous evidence was convergent (of multiple types) or replicating (similar finding repeated). Experiment 3 varied whether participants were provided with an alternative theory that explained the anomalous evidence. All experiments showed that participants' confidence changes were commensurate with the amount of anomalous evidence presented, and that larger decreases in confidence predicted theory changes. Convergent evidence and the presentation of an alternative theory led to larger confidence change. Convergent evidence also caused more theory changes. Even when people do not change theories, factors pertinent to the evidence and alternative theories decrease their confidence in their current theory and move them incrementally closer to theory change.

  13. Dogmatism of the Speaker and Selection of Evidence

    Science.gov (United States)

    Kline, John A.

    1971-01-01

    A study of the hypothesis that the type of evidence a speaker considers important might be related to how dogmatic he is. In this study, evidence was used as the dependent variable; dogmatism as the independent variable. (Author/JB)

  14. [Evidence-based management of medical disposable materials].

    Science.gov (United States)

    Yang, Hai

    2009-03-01

    Evidence-based management of medical disposable materials pays attention to collect evidence comprehensively and systematically, accumulate and create evidence through its own work and also evaluate evidence strictly. This can be used as a function to guide out job. Medical disposable materials evidence system contains product register qualification, product quality certification, supplier's behavior, internal and external communication evidence. Managers can find different ways in creating and using evidence referring to specific inside and outside condition. Evidence-based management can help accelerating the development of management of medical disposable materials from traditional experience pattern to a systematic and scientific pattern. It also has the very important meaning to improve medical quality, control the unreasonable growth of medical expense and make purchase and supply chain be more efficient. PMID:19565800

  15. Evidence Based Practice Outside the Box (Editorial

    Directory of Open Access Journals (Sweden)

    Lindsay Glynn

    2008-09-01

    Full Text Available I love food. I love cooking, baking, testing, and eating. I read about food preparation, food facts, and food service. Over the years I’ve developed my fair share of knowledge about cooking and I’m a decent cook, but I’m no chef. I guess I’m what you’d call a “foodie”. However, I have the good fortune to have a friend who is a chef and owns one of the best, and certainly the most innovative, restaurants in town. During this summer I hosted a cooking class in my home for my family with my chef friend as instructor. The Tex-Mex barbecue theme was a big hit (you can contact me for recipes, if you like, but much more fascinating was the explanation of the science behind the cooking. It turns out that there is a term for this: molecular gastronomy. Another term, and hence the genesis of my “Eureka!” moment of the summer, is evidence based cooking. Good cooking is not just following a recipe (not all of which are evidence based but at its best is the culmination of heaps of tested information regarding why and how chemical and environmental factors work together to result in a gastronomical delight. For example, will brining or marinating a pork chop make it moister? And, if brining, what temperature should the water be, how long should it soak, and how much salt is needed? Why does pounding meat increase its tenderness? What will keep guacamole from browning better – the pit or lime juice? What does baking soda do in a chocolate cake? Eggs or no eggs in fresh pasta? Like most librarians, I tend not to take information at face value. I want to know where information comes from and whether or not it is valid, based on specific factors. I’ve come to notice that evidence based, or evidence informed, practice is everywhere and has a tremendous impact on our lives. Why do you rotate the tires on your car? Evidence shows that the front tires wear more quickly (think about all those 3-pointturns, the braking, etc and therefore

  16. Decision fusion recognition based on modified evidence rule

    Institute of Scientific and Technical Information of China (English)

    黎湘; 刘永祥; 付耀文; 庄钊文

    2001-01-01

    A modified evidence combination rule with a combination parameter λ is proposed to solve some problems in D-S theory by considering the correlation and complement among the evidences as well as the size and intersection of subsets in evidence. It can get reasonable results even the evidences are conflicting. Applying this rule to the real infrared/millimetre wave fusion system, a satisfactory result has been obtained.

  17. Ambiguity, Processing Strategy, and Advertising-Evidence Interactions.

    OpenAIRE

    Ha, Young-Won; Stephen J. Hoch

    1989-01-01

    Although advertising persuades through overt appeals to reason or emotion, we focus on the indirect process by which advertising influences the interpretation of objective product evidence. We investigate how two factors moderate advertising-evidence interactions: the ambiguity of the evidence and consumer information processing strategies. We provide a theoretical account of ambiguity, identifying structural characteristics that render evidence about product quality open to either one or mul...

  18. Portuguese version of the evidence-based practice questionnaire

    OpenAIRE

    Pereira, Rui Pedro Gomes; Guerra, Ana; Peixoto, Maria José; Martins, Teresa; Barbieri, Maria do Céu; Carneiro, António Vaz

    2014-01-01

    1. Objectives: Evidence-based practice is defined as the process by which nurses make clinical decisions using the best available scientific evidence, according with their clinical experience and patient preferences in the context of available resources. The Evidence-Based Practice Questionnaire (EBPQ) developed by Upton & Upton (2006) was designed to collect information and opinions on the use of evidence-based practices by health professionals and is validating its important so that it can ...

  19. Digital Evidence and Forensic Readiness (Dagstuhl Seminar 14092)

    OpenAIRE

    Dardick, Glenn S.; Endicott-Popovsky, Barbara; Gladyshev, Pavel; Kemmerich, Thomas; Rudolph, Carsten

    2014-01-01

    The seminar on Digital Evidence and Forensic Readiness provided the space for interdisciplinary discussions on clearly defined critical aspects of engineering issues, evaluation and processes for secure digital evidence and forensic readiness. A large gap exists between the state-of-the-art in IT security and best-practice procedures for digital evidence. Experts from IT and law used this seminar to develop a common view on what exactly can be considered secure and admissible digital evidence...

  20. Evidence-based treatment of metabolic myopathy

    Directory of Open Access Journals (Sweden)

    Yan LIN

    2014-05-01

    Full Text Available Objective To evaluate the current treatments and possible adverse reactions of metabolic myopathy, and to develop the best solution for evidence-based treatment.  Methods Taking metabolic myopathy, mitochondrial myopathy, lipid storage myopathy, glycogen storage diseases, endocrine myopathy, drug toxicity myopathy and treatment as search terms, retrieve in databases such as PubMed, Cochrane Library, ClinicalKey database, National Science and Technology Library (NSTL, in order to collect the relevant literature database including clinical guidelines, systematic reviews (SR, randomized controlled trials (RCT, controlled clinical trials, retrospective case analysis and case study. Jadad Scale was used to evaluate the quality of literature.  Results Twenty-eight related articles were selected, including 6 clinical guidelines, 5 systematic reviews, 10 randomized controlled trials and 7 clinical controlled trials. According to Jadad Scale, 23 articles were evaluated as high-quality literature (≥ 4, and the remaining 5 were evaluated as low-quality literature (< 4. Treatment principles of these clinical trials, efficacy of different therapies and drug safety evaluation suggest that: 1 Acid α-glycosidase (GAA enzyme replacement therapy (ERT is the main treatment for glycogen storage diseases, with taking a high-protein diet, exercising before taking a small amount of fructose orally and reducing the patient's physical activity gradually. 2 Carnitine supplementation is used in the treatment of lipid storage myopathy, with carbohydrate and low fat diet provided before exercise or sports. 3 Patients with mitochondrial myopathy can take coenzyme Q10, vitamin B, vitamin K, vitamin C, etc. Proper aerobic exercise combined with strength training is safe, and it can also enhance the exercise tolerance of patients effectively. 4 The first choice to treat the endocrine myopathy is treating primary affection. 5 Myopathies due to drugs and toxins should

  1. 20 CFR 725.456 - Introduction of documentary evidence.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Introduction of documentary evidence. 725.456... FEDERAL MINE SAFETY AND HEALTH ACT, AS AMENDED Hearings § 725.456 Introduction of documentary evidence. (a... into evidence by the administrative law judge, subject to objection by any party. (b)(1)...

  2. 46 CFR 12.13-3 - Basis of documentary evidence.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Basis of documentary evidence. 12.13-3 Section 12.13-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MERCHANT MARINE OFFICERS AND SEAMEN REQUIREMENTS FOR... documentary evidence. The Officer in Charge, Marine Inspection will issue such documentary evidence to...

  3. 42 CFR 405.1118 - Obtaining evidence from the MAC.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Obtaining evidence from the MAC. 405.1118 Section... Council Review § 405.1118 Obtaining evidence from the MAC. A party may request and receive a copy of all... these items. If a party requests evidence from the MAC and an opportunity to comment on that...

  4. 42 CFR 423.2118 - Obtaining evidence from the MAC.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Obtaining evidence from the MAC. 423.2118 Section..., MAC review, and Judicial Review § 423.2118 Obtaining evidence from the MAC. An enrollee may request... the costs of providing these items. If an enrollee requests evidence from the MAC and an...

  5. Evidence Valued and Used by Health Promotion Practitioners

    Science.gov (United States)

    Li, V.; Carter, S. M.; Rychetnik, L.

    2015-01-01

    The use of evidence has become a foundational part of health promotion practice. Although there is a general consensus that adopting an evidence-based approach is necessary for practice, disagreement remains about what types of evidence practitioners should use to guide their work. An empirical understanding of how practitioners conceptualize and…

  6. Application of Evidence-based Prosthodontics in Practice

    Institute of Scientific and Technical Information of China (English)

    雷雨; 朱智敏; CHAO Yong-lie; SHI Zong-dao; MENG Yu-kun

    2006-01-01

    The concepts and progress of evidence-based dentistry were introduced in this critical review. An extensive PubMed search was conducted to provide sound evidences for some frequently encountered problems in prosthodontic daily practice. Conlusively, it is important for prosthodontists to keep current by looking for efficient ways of interpreting high quality evidences to clinical practice.

  7. 20 CFR 366.5 - Consideration of evidence.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Consideration of evidence. 366.5 Section 366... COLLECTION OF DEBTS BY FEDERAL TAX REFUND OFFSET § 366.5 Consideration of evidence. Evidence submitted by the... of such debt is past-due and legally enforceable will be made only by such officials or employees....

  8. Evidence-Based Medicine in the Education of Psychiatrists

    Science.gov (United States)

    Srihari, Vinod

    2008-01-01

    Objective: Evidence-based medicine has an important place in the teaching and practice of psychiatry. Attempts to teach evidence-based medicine skills can be weakened by conceptual confusions feeding a false polarization between traditional clinical skills and evidence-based medicine. Methods: The author develops a broader conception of clinical…

  9. Evidence into practice; upper respiratory tract infections in children

    NARCIS (Netherlands)

    Boonacker, C.W.B.

    2012-01-01

    Transfer of evidence into practice is often slow and therefore remains an important challenge. Factors influencing this process include awareness and agreement with available evidence, feelings about the applicability of the evidence to one’s own patients and pressure from patients to start or refra

  10. 29 CFR 2700.63 - Evidence; presentation of case.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Evidence; presentation of case. 2700.63 Section 2700.63 Labor Regulations Relating to Labor (Continued) FEDERAL MINE SAFETY AND HEALTH REVIEW COMMISSION PROCEDURAL RULES Hearings § 2700.63 Evidence; presentation of case. (a) Relevant evidence, including...

  11. Unlawfully Obtained Evidences in Turkish Criminal Procedure Law

    OpenAIRE

    DEMİRAL BAKIRMAN, Büşra

    2015-01-01

    Evidences have a great significance in criminal procedural law to find out material truths. However, there must be some restrictions on obtaining and assessing evidences in a criminal procedure based on the rule of law. The aim of this study is to show the legislative outlook of the current legislation regarding unlawfully obtained evidences in Turkish criminal procedure law

  12. Prosecuting Child Sexual Abuse: The Importance of Evidence Type

    Science.gov (United States)

    Walsh, Wendy A.; Jones, Lisa M.; Cross, Theodore P.; Lippert, Tonya

    2010-01-01

    Corroborating evidence has been associated with a decrease in children's distress during the court process, yet few studies have empirically examined the impact of evidence type on prosecution rates. This study examined the types of evidence and whether charges were filed in a sample of child sexual abuse cases (n = 329). Cases with a child…

  13. 40 CFR 10.4 - Evidence to be submitted.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Evidence to be submitted. 10.4 Section... FEDERAL TORT CLAIMS ACT Procedures § 10.4 Evidence to be submitted. (a) Death. In support of a claim based on death, the claimant may be required to submit the following evidence or information: (1)...

  14. 42 CFR 423.586 - Opportunity to submit evidence.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Opportunity to submit evidence. 423.586 Section 423..., Redeterminations, and Reconsiderations § 423.586 Opportunity to submit evidence. The Part D plan sponsor must... enrollee or the prescribing physician or other prescriber of the conditions for submitting the evidence....

  15. 20 CFR 410.475 - Failure to submit evidence.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Failure to submit evidence. 410.475 Section... Failure to submit evidence. An individual shall not be determined to be totally disabled unless he... individual from submitting evidence of disability....

  16. 42 CFR 405.809 - Opportunity to submit evidence.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Opportunity to submit evidence. 405.809 Section 405... Program § 405.809 Opportunity to submit evidence. The parties to the review (as provided for in § 405.807(a)) shall have a reasonable opportunity to submit written evidence and contentions as to fact or...

  17. 42 CFR 422.586 - Opportunity to submit evidence.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Opportunity to submit evidence. 422.586 Section 422... § 422.586 Opportunity to submit evidence. The MA organization must provide the parties to the... organization must inform the parties of the conditions for submitting the evidence....

  18. How Do Dentists Understand Evidence and Adopt It in Practice?

    Science.gov (United States)

    Sbaraini, Alexandra; Carter, Stacy M.; Evans, R. Wendell

    2012-01-01

    Although there is now a large evidence-based dentistry literature, previous investigators have shown that dentists often consider research evidence irrelevant to their practice. To understand why this is the case, we conducted a qualitative study. Objective: Our aim was to identify how dentists define evidence and how they adopt it in practice.…

  19. 20 CFR 404.704 - Your responsibility for giving evidence.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Your responsibility for giving evidence. 404.704 Section 404.704 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Evidence General § 404.704 Your responsibility for giving evidence....

  20. Evidence-based medicine in general practice specialty training

    NARCIS (Netherlands)

    S.E. Zwolsman

    2012-01-01

    Aio’s huisartsgeneeskunde hebben adequate kennis ten aanzien van evidence-based medicine (geneeskunde op basis van bewijs). In de huisartspraktijk is evidence-based gedrag vaak niet direct zichtbaar, maar artsen kunnen wel aangeven op welk aspect van evidence-based medicine de voorgeschreven behande

  1. [Hierarchy of evidence: levels of evidence and grades of recommendation from current use].

    Science.gov (United States)

    Manterola, Carlos; Asenjo-Lobos, Claudla; Otzen, Tamara

    2014-12-01

    There are multiple proposals and classifications that hierarchize evidence, which may confuse those who are dedicated to generate it both in health technology assessments, as for the development of clinical guidelines, etc. The aim of this manuscript is to describe the most commonly used classifications of levels of evidence and grades of recommendation, analyzing their main differences and applications so that the user can choose the one that better suits your needs and take this health decisions basing their practice on the best available evidence. A systematic literature search was performed in PubMed and MEDLINE databases and in Google, Yahoo and Ixquick search engines. A wealth of information concerning levels of evidence and degrees recommendation was obtained. It was summarized the information of the 11 proposals more currently used (CTFPHC, Sackett, USPSTF, CEBM, GRADE, SIGN, NICE, NHMRC, PCCRP, ADA y ACCF/AHA), between which it emphasizes the GRADE WORKING GROUP, incorporated by around 90 national and international organizations such as the World Health Organization, The Cochrane Library, American College of Physicians, American Thoracic Society, UpToDate, etc.; and locally by the Ministry of Health to create clinical practice guidelines.

  2. Toward Evidence-Based Transport of Evidence-Based Treatments: MST as an Example

    Science.gov (United States)

    Schoenwald, Sonja K.

    2008-01-01

    This article describes the journey toward evidence-based transport and implementation in usual care settings of Multisystemic Therapy (MST) for youth with drug abuse and behavioral problems (Henggeler, Schoenwald, Borduin, Rowland, & Cunningham, 1998). Research and experience informing the design of the MST transport strategy, progress in…

  3. Operationalizing Evidence-Based Practice: The Development of an Institute for Evidence-Based Social Work

    Science.gov (United States)

    Regehr, Cheryl; Stern, Susan; Shlonsky, Aron

    2007-01-01

    Although evidence-based practice (EBP) has received increasing attention in social work in the past few years, there has been limited success in moving from academic discussion to engaging social workers in the process of implementing EBP in practice. This article describes the challenges, successes, and future aims in the process of developing a…

  4. Nursing implementation science: how evidence-based nursing requires evidence-based implementation.

    NARCIS (Netherlands)

    Achterberg, T. van; Schoonhoven, L.J.; Grol, R.P.T.M.

    2008-01-01

    PURPOSE: Evidence is not always used in practice, and many examples of problematic implementation of research into practice exist. The aim of this paper is to provide an introduction and overview of current developments in implementation science and to apply these to nursing. METHODS: We discuss a f

  5. Evidence-Based Practice and School Libraries: Interconnections of Evidence, Advocacy, and Actions

    Science.gov (United States)

    Todd, Ross J.

    2015-01-01

    This author states that a professional focus on evidence based practice (EBP) for school libraries emerged from the International Association of School Librarianship conference when he presented the concept. He challenged the school library profession to actively engage in professional and reflective practices that chart, measure, document, and…

  6. Is There Neural Evidence for an Evidence Accumulation Process in Memory Decisions?

    NARCIS (Netherlands)

    van Vugt, Marieke K; Beulen, Marijke A; Taatgen, Niels A

    2016-01-01

    Models of evidence accumulation have been very successful at describing human decision making behavior. Recent years have also seen the first reports of neural correlates of this accumulation process. However, these studies have mostly focused on perceptual decision making tasks, ignoring the role o

  7. Dinosaur physiology. Evidence for mesothermy in dinosaurs.

    Science.gov (United States)

    Grady, John M; Enquist, Brian J; Dettweiler-Robinson, Eva; Wright, Natalie A; Smith, Felisa A

    2014-06-13

    Were dinosaurs ectotherms or fast-metabolizing endotherms whose activities were unconstrained by temperature? To date, some of the strongest evidence for endothermy comes from the rapid growth rates derived from the analysis of fossil bones. However, these studies are constrained by a lack of comparative data and an appropriate energetic framework. Here we compile data on ontogenetic growth for extant and fossil vertebrates, including all major dinosaur clades. Using a metabolic scaling approach, we find that growth and metabolic rates follow theoretical predictions across clades, although some groups deviate. Moreover, when the effects of size and temperature are considered, dinosaur metabolic rates were intermediate to those of endotherms and ectotherms and closest to those of extant mesotherms. Our results suggest that the modern dichotomy of endothermic versus ectothermic is overly simplistic.

  8. Dark Energy: Observational Evidence and Theoretical Models

    CERN Document Server

    Novosyadlyj, B; Shtanov, Yu; Zhuk, A

    2015-01-01

    The book elucidates the current state of the dark energy problem and presents the results of the authors, who work in this area. It describes the observational evidence for the existence of dark energy, the methods and results of constraining of its parameters, modeling of dark energy by scalar fields, the space-times with extra spatial dimensions, especially Kaluza---Klein models, the braneworld models with a single extra dimension as well as the problems of positive definition of gravitational energy in General Relativity, energy conditions and consequences of their violation in the presence of dark energy. This monograph is intended for science professionals, educators and graduate students, specializing in general relativity, cosmology, field theory and particle physics.

  9. [Medical anthropology evidences on the Pishtaco origin].

    Science.gov (United States)

    de Pribyl, Rosario

    2010-03-01

    This paper will contribute to the scientific development of a new approach on the pishtaco in Peru by means of medical anthropological analysis. The model emphasizes presentation and analysis of historical, pharmaceutical, and anthropological evidence supporting use of human tissues with specific medical goals in Peruvian and European regions. We can find the origin of this phenomenon around the sixteen and seventeen centuries in Europe: The pishtaco has no an Andean origin. The methodology and main conclusions of this paper could provide to the scientific community an alternative perspective to the conventional anthropological and ethnological research, as an example of a medical anthropological analysis of the pishtaco character. Professionals involved in intercultural health projects could have a new insight on this issue thanks to these results. They will obtain an adequate historical-cultural context for the interpretation and understanding of people and native communities' beliefs about health, body and medical systems.

  10. Dairy propionibacteria as probiotics: recent evidences.

    Science.gov (United States)

    Altieri, Clelia

    2016-10-01

    Nowdays there is evidence that dairy propionibacteria display probiotic properties, which as yet have been underestimated. The aim of this paper is to review the recent highlights of data representing the probiotic potential of dairy propionibacteria, studied both by general selection criteria (useful for all probiotic potentials), and by more specific and innovative approach. Dairy propionibacteria show a robust nature, that makes them able to overcome technological hurdles, allowing their future use in various fermented probiotic foods. In addition to the general selection criteria for probiotics in areas such as food safety, technological and digestive stress tolerance, many potential health benefits have been recently described for dairy propionibacteria, including, production of several active molecules and adhesion capability, that can mean a steady action in modulation of microbiota and of metabolic activity in the gut; their impact on intestinal inflammation, modulation of the immune system, potential modulation of risk factors for cancer development modulation of intestinal absorption. PMID:27565782

  11. An information gap in DNA evidence interpretation.

    Directory of Open Access Journals (Sweden)

    Mark W Perlin

    Full Text Available Forensic DNA evidence often contains mixtures of multiple contributors, or is present in low template amounts. The resulting data signals may appear to be relatively uninformative when interpreted using qualitative inclusion-based methods. However, these same data can yield greater identification information when interpreted by computer using quantitative data-modeling methods. This study applies both qualitative and quantitative interpretation methods to a well-characterized DNA mixture and dilution data set, and compares the inferred match information. The results show that qualitative interpretation loses identification power at low culprit DNA quantities (below 100 pg, but that quantitative methods produce useful information down into the 10 pg range. Thus there is a ten-fold information gap that separates the qualitative and quantitative DNA mixture interpretation approaches. With low quantities of culprit DNA (10 pg to 100 pg, computer-based quantitative interpretation provides greater match sensitivity.

  12. Lasers In Physical Evidence Examination: An Overview

    Science.gov (United States)

    Menzel, E. R.

    1987-01-01

    A recent application of fluorescence that is perhaps largely unknown outside law enforcement involves the utilization of laser excited fluorescence (LEF) in forensic science. In this overview, the focus is on LEF applicaton to development of latent fingerprints. Other areas of criminalistics, such as document examination and fiber analysis will be dealt with briefly only. To bring the technical reader, who likely has little familiarity with the fingerprint field, up to stream, a historical introduction precedes the description of current procedures for laser detection of latent fingerprints which is followed by a brief outline of current areas of research in the fingerprint area and application of lasers to other types of evidence examination. The overview concludes with an assessment of the current state and utilization growth prognosis of lasers in criminalistics.

  13. Neural evidence that suspense narrows attentional focus.

    Science.gov (United States)

    Bezdek, M A; Gerrig, R J; Wenzel, W G; Shin, J; Pirog Revill, K; Schumacher, E H

    2015-09-10

    The scope of visual attention changes dynamically over time. Although previous research has reported conditions that suppress peripheral visual processing, no prior work has investigated how attention changes in response to the variable emotional content of audiovisual narratives. We used fMRI to test for the suppression of spatially peripheral stimuli and enhancement of narrative-relevant central stimuli at moments when suspense increased in narrative film excerpts. Participants viewed films presented at fixation, while flashing checkerboards appeared in the periphery. Analyses revealed that increasing narrative suspense caused reduced activity in peripheral visual processing regions in the anterior calcarine sulcus and in default mode network nodes. Concurrently, activity increased in central visual processing regions and in frontal and parietal regions recruited for attention and dynamic visual processing. These results provide evidence, using naturalistic stimuli, of dynamic spatial tuning of attention in early visual processing areas due to narrative context. PMID:26143014

  14. Intellectual capital: Evidence from banking industry

    Directory of Open Access Journals (Sweden)

    Somayeh Boostani

    2014-09-01

    Full Text Available This paper investigates different components on intellectual capital including human capital, structural capital and customer capital in banking industry in city of Salmas, Iran. The study uses the questionnaire developed by Bontis (1998 [Bontis, N. (1998. Intellectual capital: an exploratory study that develops measures and models. Management Decision, 36(2, 63-76.] to measure the effects of human capital. The questionnaire consists of 42 questions and all of them are designed in Likert scale. Cronbach alphas for human capital, structural capital and relationship capital were calculated as 0.79, 0.76 and 0.72, respectively. The implementation of Kolmogorov-Smirnov test has indicated that the data were normally distributed. Using t-student test, the study determined that while management team did not pay enough attention on human capital, there were some statistically significant evidence that social and relationship capitals gained good attention.

  15. Reducing Emergency Department Crowding: Evidence Based Strategies.

    Science.gov (United States)

    Khalifa, Mohamed; Zabani, Ibrahim

    2016-01-01

    Emergency department (ED) crowding has become a major barrier to receiving timely care. King Faisal Specialist Hospital & Research Center, Saudi Arabia worked on identifying evidence based strategies for reducing the ED crowding by improving the intake. In addition to a review of literature, qualitative survey methods were used to identify strategies, which were classified into 10 suggested procedures categorized into three types of changes. Physical improvements include using physician cubicles, creating a team triage area and an internal waiting area for less acute patients instead of occupying beds. Technology improvements; include using informatics to update the electronic emergency record with information, using palmar scanning to instantly identify patients and using radio communication devices. Process improvements; include a scribe program to decrease clerical documentation tasks, switching between low flow and high flow processes, placing a physician in triage and using patient segmentation methods. PMID:27350468

  16. EVIDENCE-BASED USE OF EPLERENONE

    Directory of Open Access Journals (Sweden)

    S. R. Gilyarevski

    2014-07-01

    Full Text Available Data of the negative effect of high concentrations of aldosterone in the blood for cardiovascular disease, which served as the theoretical basis for wider use in clinical practice of the drugs belonging to the class of aldosterone receptor blockers is presented. Evidence-based data on efficacy and safety of aldosterone receptor blockers, which were obtained in the course of several randomized clinical trials is performed. Particular attention is paid to aspects of the clinical use of selective aldosterone receptor blocker eplerenone, including current data, which makes reasonable extension of indications for its use in treating patients with chronic heart failure. Data on indications of eplerenone use in patients with hypertension, especially in the case of associated target organ damage is presented.

  17. Evidence for a Lattice Weak Gravity Conjecture

    CERN Document Server

    Heidenreich, Ben; Rudelius, Tom

    2016-01-01

    The Weak Gravity Conjecture postulates the existence of superextremal charged particles, i.e. those with mass smaller than or equal to their charge in Planck units. We present further evidence for our recent observation that in known examples a much stronger statement is true: an infinite tower of superextremal particles of different charges exists. We show that effective Kaluza-Klein field theories and perturbative string vacua respect the Sublattice Weak Gravity Conjecture, namely that a finite index sublattice of the full charge lattice exists with a superextremal particle at each site. In perturbative string theory we show that this follows from modular invariance. However, we present counterexamples to the stronger possibility that a superextremal state exists at every lattice site, including an example in which the lightest charged state is subextremal. The Sublattice Weak Gravity Conjecture has many implications both for abstract theories of quantum gravity and for real-world physics. For instance, it ...

  18. Evidence of platelet activation in multiple sclerosis

    Directory of Open Access Journals (Sweden)

    Alexander J Steven

    2008-06-01

    Full Text Available Abstract Objective A fatality in one multiple sclerosis (MS patient due to acute idiopathic thrombocytopenic purpura (ITP and a near fatality in another stimulated our interest in platelet function abnormalities in MS. Previously, we presented evidence of platelet activation in a small cohort of treatment-naive MS patients. Methods In this report, 92 normal controls and 33 stable, untreated MS patients were studied. Platelet counts, measures of platelet activation [plasma platelet microparticles (PMP, P-selectin expression (CD62p, circulating platelet microaggragtes (PAg], as well as platelet-associated IgG/IgM, were carried out. In addition, plasma protein S activity was measured. Results Compared to controls, PMP were significantly elevated in MS (p Conclusion Platelets are significantly activated in MS patients. The mechanisms underlying this activation and its significance to MS are unknown. Additional study of platelet activation and function in MS patients is warranted.

  19. EVIDENCE-BASED USE OF EPLERENONE

    Directory of Open Access Journals (Sweden)

    S. R. Gilyarevski

    2012-01-01

    Full Text Available Data of the negative effect of high concentrations of aldosterone in the blood for cardiovascular disease, which served as the theoretical basis for wider use in clinical practice of the drugs belonging to the class of aldosterone receptor blockers is presented. Evidence-based data on efficacy and safety of aldosterone receptor blockers, which were obtained in the course of several randomized clinical trials is performed. Particular attention is paid to aspects of the clinical use of selective aldosterone receptor blocker eplerenone, including current data, which makes reasonable extension of indications for its use in treating patients with chronic heart failure. Data on indications of eplerenone use in patients with hypertension, especially in the case of associated target organ damage is presented.

  20. Tongue tie: the evidence for frenotomy.

    Science.gov (United States)

    Brookes, Alastair; Bowley, Douglas M

    2014-11-01

    Tongue tie or ankyloglossia is a congenital variation characterised by a short lingual frenulum which may result in restriction of tongue movement and thus impact on function. Tongue tie division (frenotomy) in affected infants with breastfeeding problems yields objective improvements in milk production and breastfeeding characteristics, including objective scoring measures, weight gain and reductions in maternal pain. For the majority of mothers, frenotomy appears to enhance maintenance of breastfeeding. Tongue tie division is a safe procedure with minimal complications. The commonest complication is minor bleeding. Recurrence leading to redivision occurs with rates of 0.003-13% reported; this appears to be more common with posterior than anterior ties. There are limited reports indicating that prophylactic frenotomy may promote subsequent speech development; however, evidence is currently insufficient to condone this practice and further good quality research into this area is warranted. PMID:25258296