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Sample records for antiproton radiotherapy peripheral

  1. Antiproton Radiotherapy Peripheral Dose from Secondary Neutrons produced in the Annihilation of Antiprotons in the Target

    CERN Document Server

    Fahimian, Benjamin P; Keyes, Roy; Bassler, Niels; Iwamoto, Keisuke S; Zankl, Maria; Holzscheiter, Michael H

    2009-01-01

    The AD-4/ACE collaboration studies the biological effects of antiprotons with respect to a possible use of antiprotons in cancer therapy. In vitro experiments performed by the collaboration have shown an enhanced biological effectiveness for antiprotons relative to protons. One concern is the normal tissue dose resulting from secondary neutrons produced in the annihilation of antiprotons on the nucleons of the target atoms. Here we present the first organ specific Monte Carlo calculations of normal tissue equivalent neutron dose in antiproton therapy through the use of a segmented CT-based human phantom. The MCNPX Monte Carlo code was employed to quantify the peripheral dose for a cylindrical spread out Bragg peak representing a treatment volume of 1 cm diameter and 1 cm length in the frontal lobe of a segmented whole-body phantom of a 38 year old male. The secondary neutron organ dose was tallied as a function of energy and organ.

  2. Antiproton radiotherapy

    CERN Document Server

    Bassler, Niels; Beyer, Gerd; DeMarco, John J.; Doser, Michael; Hajdukovic, Dragan; Hartley, Oliver; Iwamoto, Keisuke S.; Jakel, Oliver; Knudsen, Helge V.; Kovacevic, Sandra; Møller, Søren Pape; Overgaard, Jens; Petersen, Jørgen B.à; Solberg, Timothy D.; Sørensen, Brita S.; Vranjes, Sanja; Wouters, Bradly G.; Holzscheiter, Michael H.

    2008-01-01

    Antiprotons are interesting as a possible future modality in radiation therapy for the following reasons: When fast antiprotons penetrate matter, protons and antiprotons have near identical stopping powers and exhibit equal radiobiology well before the Bragg-peak. But when the antiprotons come to rest at the Bragg-peak, they annihilate, releasing almost 2 GeV per antiproton–proton annihilation. Most of this energy is carried away by energetic pions, but the Bragg-peak of the antiprotons is still locally augmented with ∼20–30 MeV per antiproton. Apart from the gain in physical dose, an increased relative biological effect also has been observed, which can be explained by the fact that some of the secondary particles from the antiproton annihilation exhibit high-LET properties. Finally, the weakly interacting energetic pions, which are leaving the target volume, may provide a real time feedback on the exact location of the annihilation peak. We have performed dosimetry experiments and investigated the rad...

  3. Relative Biological Effectiveness and Peripheral Damage of Antiproton Annihilation

    CERN Multimedia

    Kavanagh, J N; Kaiser, F; Tegami, S; Schettino, G; Kovacevic, S; Hajdukovic, D; Knudsen, H; Currell, F J; Toelli, H T; Doser, M; Holzscheiter, M; Herrmann, R; Timson, D J; Alsner, J; Landua, R; Comor, J; Moller, S P; Beyer, G

    2002-01-01

    The use of ions to deliver radiation to a body for therapeutic purposes has the potential to be significant improvement over the use of low linear energy transfer (LET) radiation because of the improved energy deposition profile and the enhanced biological effects of ions relative to photons. Proton therapy centers exist and are being used to treat patients. In addition, the initial use of heavy ions such as carbon is promising to the point that new treatment facilities are planned. Just as with protons or heavy ions, antiprotons can be used to deliver radiation to the body in a controlled way; however antiprotons will exhibit additional energy deposition due to annihilation of the antiprotons within the body. The slowing down of antiprotons in matter is similar to that of protons except at the very end of the range beyond the Bragg peak. Gray and Kalogeropoulos estimated the additional energy deposited by heavy nuclear fragments within a few millimeters of the annihilation vertex to be approximately 30 MeV (...

  4. Simulation of an antiprotons beam applied to the radiotherapy

    International Nuclear Information System (INIS)

    Prata, Leonardo de Almeida

    2006-07-01

    Results for the interaction of a antiproton beam with constituent nuclei of the organic matter are presented. This method regards of the application of an computational algorithm to determine quantitatively the differential cross sections for the scattered particles, starting from the interaction of these antiprotons with the nuclei, what will allow in the future to draw the isodose curve for antiproton therapy, once these beams are expected to be used in cancer treatment soon. The calculation will be done through the application of the concepts of the method of intranuclear cascade, providing yield and differential cross sections of the scattered particles, present in the software MCMC. Th algorithm was developed based on Monte Carlo's method, already taking into account a validate code. The following physical quantities are presented: the yield of secondary particles, their spectral and angular distributions for these interactions. For the energy range taken into account the more important emitted particles are protons, neutrons and pions. Results shown that emitted secondary particles can modify the isodose curves, because they present high yield and energy for transverse directions. (author)

  5. Entrance and peripheral dose measurements during radiotherapy

    International Nuclear Information System (INIS)

    Sulieman, A.; Kappas, K.; Theodorou, K.

    2008-01-01

    In vivo dosimetry of entrance dose was performed using thermoluminescent dosimeters (TLD) in order to evaluate the clinical application of the build up caps in patient dose measurements and for different treatment techniques. Peripheral dose (thyroid and skin) was measured for patients during breast radiotherapy to evaluate the probability of secondary cancer induction. TLD-100 chips were used with different Copper build up caps (for 6 MV and 15 MV photon beams from two linear accelerators. Entrance doses were measured for patients during radiotherapy course for breast, head and neck, abdomen and pelvis malignancies. The measured entrance dose for the different patients for 6 MV beams is found to be within the ±2.6% compared to the dose derived from theoretical estimation (normalized dose at D max ). The same measurements for 15 MV beams are found to be ±3 %. The perturbation value can reach up to 20% of the D max , which acts as a limitation for entrance dose measurements. An average thyroid skin dose of 3.7% of the prescribed dose was measured per treatment session while the mean skin dose breast treatment session is estimated to be 42% of D max , for both internal and external fields. These results are comparable in those of the in vivo of reported in literature. The risk of fatality due to thyroid cancer per treatment course is 3x10 -3

  6. Simulation of an antiprotons beam applied to the radiotherapy; Simulacao de um feixe de antiprotons aplicado a radioterapia

    Energy Technology Data Exchange (ETDEWEB)

    Prata, Leonardo de Almeida

    2006-07-15

    Results for the interaction of a antiproton beam with constituent nuclei of the organic matter are presented. This method regards of the application of an computational algorithm to determine quantitatively the differential cross sections for the scattered particles, starting from the interaction of these antiprotons with the nuclei, what will allow in the future to draw the isodose curve for antiproton therapy, once these beams are expected to be used in cancer treatment soon. The calculation will be done through the application of the concepts of the method of intranuclear cascade, providing yield and differential cross sections of the scattered particles, present in the software MCMC. Th algorithm was developed based on Monte Carlo's method, already taking into account a validate code. The following physical quantities are presented: the yield of secondary particles, their spectral and angular distributions for these interactions. For the energy range taken into account the more important emitted particles are protons, neutrons and pions. Results shown that emitted secondary particles can modify the isodose curves, because they present high yield and energy for transverse directions. (author)

  7. Simulation of an antiprotons beam applied to the radiotherapy; Simulacao de um feixe de antiprotons aplicado a radioterapia

    Energy Technology Data Exchange (ETDEWEB)

    Prata, Leonardo de Almeida

    2006-07-15

    Results for the interaction of a antiproton beam with constituent nuclei of the organic matter are presented. This method regards of the application of an computational algorithm to determine quantitatively the differential cross sections for the scattered particles, starting from the interaction of these antiprotons with the nuclei, what will allow in the future to draw the isodose curve for antiproton therapy, once these beams are expected to be used in cancer treatment soon. The calculation will be done through the application of the concepts of the method of intranuclear cascade, providing yield and differential cross sections of the scattered particles, present in the software MCMC. Th algorithm was developed based on Monte Carlo's method, already taking into account a validate code. The following physical quantities are presented: the yield of secondary particles, their spectral and angular distributions for these interactions. For the energy range taken into account the more important emitted particles are protons, neutrons and pions. Results shown that emitted secondary particles can modify the isodose curves, because they present high yield and energy for transverse directions. (author)

  8. Peripheral blood count in preoperative radiotherapy (with radiomodificators) of lung cancer

    International Nuclear Information System (INIS)

    Demidchik, Yu.E.; Zharkov, V.V.; Prokhorova, V.I.; Rubanova, C.Z.

    1989-01-01

    Indices of peripheral blood in 215 patients with lung cancer during preoperative radiation using hyperglycemia or metronidazole are studied. It is shown that after preoperative radiotherapy, when radiomodifying effects are not used, the content of erythrocytes, thrombocytes, leukocytes, the concentration of hemoglobin in peripheral blood, as well as erythrocyte sedimentation rare didn't change. Functional disorders of the leukopoietic function and the thrombopoietic function of bone marrow when using metronidazole are registered when applying various types of preoperative radiotherapy. Lymphopenia is established when using various types of radiotherapy with radiomodificators

  9. Influence of peripheral blood hemoglobin concentration on the result of radiotherapy for nasopharyngeal carcinoma

    International Nuclear Information System (INIS)

    He Beiwa; Zhang Guofen; Zhao Yutian; Wang Zhenwu; Xu Min; Hu Yulin

    2002-01-01

    Objective: To determine the influence of peripheral blood hemoglobin concentration on the radiotherapy result of nasopharyngeal carcinoma (NPC). Methods: From January 1989 to December 1998, 304 patients with pathologically confirmed NPC received radical radiation. There were 209 males and 95 females. The ages ranged from 16 to 77 years with a median of 42. All patients were irradiated by 60 Co or 6 MV external beam with a total dose of 64 - 76 Gy for the primary tumor and 46 - 77 Gy for the cervical lymph nodes. The peripheral blood hemoglobin concentration for all patients was measured before, during and after radiotherapy. These patients were divided into three groups according to the peripheral blood hemoglobin concentration before radiotherapy: anemia ( 160 g/L), and into two groups according to the change in the peripheral blood hemoglobin concentration during radiotherapy as increased and decreased groups. Results: All patients were followed with a follow-up rate of 90.5%. The peripheral blood hemoglobin concentration had a significant effect on the survival of NPC patients. Its decrease or increase during radiotherapy affected the survival and local control rates of NPC patients. Conclusions: The change of peripheral hemoglobin concentration affecting the oxygen content in the blood, can influence the local control and survival rates of NPC patients. Increase results in higher survival

  10. Antiproton production

    International Nuclear Information System (INIS)

    Lazarus, D.M.

    1987-01-01

    The results for the antiproton momentum spectrum produced in proton reactions on lead at the CERN Antiproton Accumulator is scaled to AGS operating conditions using the Sanford-Wang formula with no correction for target material. Yield predictions as a function of momentum are shown for 28.3 GeV protons on beryllium and results are converted to antiproton beam flux. The AGS Medium Energy Separated Beam has a flux which is a factor of 2 lower than Sanford-Wang predictions. This may be due to factors affecting beam acceptance

  11. Threshold dose for peripheral neuropathy following intraoperative radiotherapy (IORT) in a large animal model

    International Nuclear Information System (INIS)

    Kinsella, T.J.; DeLuca, A.M.; Barnes, M.; Anderson, W.; Terrill, R.; Sindelar, W.F.

    1991-01-01

    Radiation injury to peripheral nerve is a dose-limiting toxicity in the clinical application of intraoperative radiotherapy, particularly for pelvic and retroperitoneal tumors. Intraoperative radiotherapy-related peripheral neuropathy in humans receiving doses of 20-25 Gy is manifested as a mixed motor-sensory deficit beginning 6-9 months following treatment. In a previous experimental study of intraoperative radiotherapy-related neuropathy of the lumbro-sacral plexus, an approximate inverse linear relationship was reported between the intraoperative dose (20-75 Gy range) and the time to onset of hind limb paresis (1-12 mos following intraoperative radiotherapy). The principal histological lesion in irradiated nerve was loss of large nerve fibers and perineural fibrosis without significant vascular injury. Similar histological changes in irradiated nerves were found in humans. To assess peripheral nerve injury to lower doses of intraoperative radiotherapy in this same large animal model, groups of four adult American Foxhounds received doses of 10, 15, or 20 Gy to the right lumbro-sacral plexus and sciatic nerve using 9 MeV electrons. The left lumbro-sacral plexus and sciatic nerve were excluded from the intraoperative field to allow each animal to serve as its own control. Following treatment, a complete neurological exam, electromyogram, and nerve conduction studies were performed monthly for 1 year. Monthly neurological exams were performed in years 2 and 3 whereas electromyogram and nerve conduction studies were performed every 3 months during this follow-up period. With follow-up of greater than or equal to 42 months, no dog receiving 10 or 15 Gy IORT shows any clinical or laboratory evidence of peripheral nerve injury. However, all four dogs receiving 20 Gy developed right hind limb paresis at 8, 9, 9, and 12 mos following intraoperative radiotherapy

  12. Antiproton production

    International Nuclear Information System (INIS)

    Allaby, J.V.

    1984-01-01

    The basic definitions used in the physics literature on particle production are reviewed. The data on anti p production are interpreted in order to provide an estimate of the yield of anti p's from typical target at the antiproton accumulator, including the effects of re-absorption in the target. (orig.)

  13. Antiproton Target

    CERN Multimedia

    1980-01-01

    Antiproton target used for the AA (antiproton accumulator). The first type of antiproton production target used from 1980 to 1982 comprised a rod of copper 3mm diameter and 120mm long embedded in a graphite cylinder that was itself pressed into a finned aluminium container. This assembly was air-cooled and it was used in conjunction with the Van der Meer magnetic horn. In 1983 Fermilab provided us with lithium lenses to replace the horn with a view to increasing the antiproton yield by about 30%. These lenses needed a much shorter target made of heavy metal - iridium was chosen for this purpose. The 50 mm iridium rod was housed in an extension to the original finned target container so that it could be brought very close to the entrance to the lithium lens. Picture 1 shows this target assembly and Picture 2 shows it mounted together with the lithium lens. These target containers had a short lifetime due to a combination of beam heating and radiation damage. This led to the design of the water-cooled target in...

  14. The Antiproton Accumulator becomes Antiproton Decelerator

    CERN Multimedia

    1980-01-01

    The photos show the Antiproton Accumulator (AA) transformed into Antiproton Decelerator. The AA was used at CERN between 1981 and 1999 before being replaced by the Antiproton Decelerator (AD). The AA was used to collect and stochastically cool antiprotons used in proton-antiproton collisions in the SPS collider. This lead to the discovery of the W and Z bosons in 1983 and the Nobel Prize for Carlo Rubbia and Simon van der Meer in 1984.

  15. Clinical toxicity of peripheral nerve to intraoperative radiotherapy in a canine model

    International Nuclear Information System (INIS)

    Johnstone, Peter A. S.; DeLuca, Anne Marie; Bacher, John D.; Hampshire, Victoria A.; Terrill, Richard E.; Anderson, William J.; Kinsella, Timothy J.; Sindelar, William F.

    1995-01-01

    Purpose: The clinical late effects of intraoperative radiotherapy (IORT) on peripheral nerve were investigated in a foxhound model. Methods and Materials: Between 1982 and 1987, 40 animals underwent laparotomy with intraoperative radiotherapy of doses from 0-75 Gy administered to the right lumbosacral plexus. Subsequently, all animals were monitored closely and sacrificed to assess clinical effects to peripheral nerve. This analysis reports final clinical results of all animals, with follow-up to 5 years. Results: All animals treated with ≥ 25 Gy developed ipsilateral neuropathy. An inverse relationship was noted between intraoperative radiotherapy dose and time to neuropathy, with an effective dose for 50% paralysis (ED 50 ) of 17.2 Gy. One of the animals treated with 15 Gy IORT developed paralysis, after a much longer latency than the other animals. Conclusions: Doses of 15 Gy delivered intraoperatively may be accompanied by peripheral neuropathy with long-term follow-up. This threshold is less than that reported with shorter follow-up. The value of ED 50 determined here is in keeping with data from other animal trials, and from clinical trials in humans

  16. Peripheral lymphocyte subset variation predicts prostate cancer carbon ion radiotherapy outcomes

    Science.gov (United States)

    Shi, Ze-Liang; Li, Bing-Xin; Wu, Xian-Wei; Li, Ping; Zhang, Qing; Wei, Xun-Bin; Fu, Shen

    2016-01-01

    The immune system plays a complementary role in the cytotoxic activity of radiotherapy. Here, we examined changes in immune cell subsets after heavy ion therapy for prostate cancer. The lymphocyte counts were compared with acute radiotherapy-related toxicity, defined according to the Common Terminology Criteria for Adverse Events, and short-term local efficacy, defined based on prostate-specific antigen concentrations. Confirmed prostate cancer patients who had not received previous radiotherapy were administered carbon ion radiotherapy (CIR) in daily fractions of 2.74 GyE with a total dose of 63-66 GyE. Lymphocyte subset counts were investigated before, during and after radiotherapy, and at a 1 month follow-up. Most notable among our findings, the CD4/CD8 ratio and CD19+ cell counts were consistently higher in patients with a complete response (CR) or partial response (PR) to CIR than in those classified in the stable disease (SD) group (P<0.05 for both). But CD3+ and CD8+ cell counts were lower in the CR and PR groups than in the SD group. These results indicate that variations in peripheral lymphocyte subpopulations are predictive of outcome after CIR for prostate cancer. PMID:27029063

  17. Radiotherapy.

    Science.gov (United States)

    Krause, Sonja; Debus, Jürgen; Neuhof, Dirk

    2011-01-01

    Solitary plasmocytoma occurring in bone (solitary plasmocytoma of the bone, SBP) or in soft tissue (extramedullary plasmocytoma, EP) can be treated effectively and with little toxicity by local radiotherapy. Ten-year local control rates of up to 90% can be achieved. Patients with multiple myeloma often suffer from symptoms such as pain or neurological impairments that are amenable to palliative radiotherapy. In a palliative setting, short treatment schedules and lower radiation doses are used to reduce toxicity and duration of hospitalization. In future, low-dose total body irradiation (TBI) may play a role in a potentially curative regimen with nonmyeloablative conditioning followed by allogenic peripheral blood stem cell transplantation.

  18. The biological effectiveness of antiproton irradiation

    International Nuclear Information System (INIS)

    Holzscheiter, Michael H.; Bassler, Niels; Agazaryan, Nzhde; Beyer, Gerd; Blackmore, Ewart; DeMarco, John J.; Doser, Michael; Durand, Ralph E.; Hartley, Oliver; Iwamoto, Keisuke S.; Knudsen, Helge V.; Landua, Rolf; Maggiore, Carl; McBride, William H.; Moller, Soren Pape; Petersen, Jorgen; Skarsgard, Lloyd D.; Smathers, James B.; Solberg, Timothy D.; Uggerhoj, Ulrik I.; Vranjes, Sanja; Withers, H. Rodney; Wong, Michelle; Wouters, Bradly G.

    2006-01-01

    Background and purpose: Antiprotons travel through tissue in a manner similar to that for protons until they reach the end of their range where they annihilate and deposit additional energy. This makes them potentially interesting for radiotherapy. The aim of this study was to conduct the first ever measurements of the biological effectiveness of antiprotons. Materials and methods: V79 cells were suspended in a semi-solid matrix and irradiated with 46.7 MeV antiprotons, 48 MeV protons, or 6 Co γ-rays. Clonogenic survival was determined as a function of depth along the particle beams. Dose and particle fluence response relationships were constructed from data in the plateau and Bragg peak regions of the beams and used to assess the biological effectiveness. Results: Due to uncertainties in antiproton dosimetry we defined a new term, called the biologically effective dose ratio (BEDR), which compares the response in a minimally spread out Bragg peak (SOBP) to that in the plateau as a function of particle fluence. This value was ∼3.75 times larger for antiprotons than for protons. This increase arises due to the increased dose deposited in the Bragg peak by annihilation and because this dose has a higher relative biological effectiveness (RBE). Conclusion: We have produced the first measurements of the biological consequences of antiproton irradiation. These data substantiate theoretical predictions of the biological effects of antiproton annihilation within the Bragg peak, and suggest antiprotons warrant further investigation

  19. Peripheral doses in modulated intensive radiotherapy (MIRT) and its implications in radiological protection

    International Nuclear Information System (INIS)

    Cobos, Agustin C.; Sanz, Dario E.; Alvarez, Guilhermo D.

    2013-01-01

    A calculation model based on the theory of photon transport, to estimate the peripheral energy fluence (fluence occurring outside the radiation beam) produced by the dispersions of photon compensating filters used was developed in IMRT mode, in a treatment room radiotherapy service of FUESMEN. In order to validate the model were experimentally determined fluences and peripheral dose for three different sizes of compensating filters. It was found that there is a slight systematic overestimation model with respect to experimental results. The experimental values also allowed the comparison of the peripheral doses with other modalities. Furthermore, a model was developed to estimate the annual dose that occurs at any point to be protected with a shield, from the theoretical values obtained from peripheral energy flow. Using the theoretical values automatically allowed to take a conservative approach because of the slight overestimation already mentioned, the couple have a calculation model for widespread use. It was found that the contribution of the peripheral dose to the annual dose is more than significant, thus suggesting that the same should be considered in the design calculations of secondary barriers

  20. Unstable chromosome aberrations on peripheral blood lymphocytes from patients with cervical uterine cancer following radiotherapy

    International Nuclear Information System (INIS)

    Magnata, Simey de Souza Leao Pereira

    2002-09-01

    Absorbed dose determination is an important step for risk assessment related to an exposure to ionizing radiation. However, physical dosimetry cannot be always performed, principally in the case of retrospective estimates. In this context, the use of bioindicators (biological effects) has been proposed, which defines the so-called biological dosimetry. In particular, scoring of unstable chromosomes aberrations (dicentrics, centric rings and fragments) of peripheral blood lymphocytes, while is the most reliable biological method for estimating individual exposure to ionizing radiation. In this work, blood samples from 5 patients, with cervical uterine cancer, were evaluated after partial-body radiotherapy with a source of 69 Co. For this, conventional cytogenetic method was employed, based on Giemsa coloration and fluorescence in situ hybridization, in order to correlate the frequency of unstable chromosome aberrations of blood lymphocytes with absorbed dose, as a result of the radiotherapy. A good agreement was observed between the frequency of chromosome aberrations scored and the values of dose previously calculated by physical dosimetry during patient's radiotherapy. The results presented in this work point out the importance of concerning analyses of unstable chromosome aberrations as biological dosimeter in the investigation of partial-body exposure to ionizing radiation. (author)

  1. Practical Uses of Antiprotons

    International Nuclear Information System (INIS)

    Jackson, Gerald P.

    2003-01-01

    The production of commercial quantities of antiprotons has been a reality for many years now. The deceleration and trapping of antiprotons is a relatively new activity, but has been sufficiently proven to be translated into a business enterprise. Now that NASA has a portable Penning trap for transporting antiprotons, all the elements are in place to begin the commercial distribution of antiprotons. The list of potential customers for antiprotons is continuously growing, with detailed market analyses already performed on some medical and propulsion applications. In this paper these applications are reviewed, along with their appetite for antiprotons and the steps needed to bring them to market.

  2. Practical Uses of Antiprotons

    Science.gov (United States)

    Jackson, Gerald P.

    The production of commercial quantities of antiprotons has been a reality for many years now. The deceleration and trapping of antiprotons is a relatively new activity, but has been sufficiently proven to be translated into a business enterprise. Now that NASA has a portable Penning trap for transporting antiprotons, all the elements are in place to begin the commercial distribution of antiprotons. The list of potential customers for antiprotons is continuously growing, with detailed market analyses already performed on some medical and propulsion applications. In this paper these applications are reviewed, along with their appetite for antiprotons and the steps needed to bring them to market.

  3. Physics using cold antiprotons

    CERN Document Server

    Hayano, R S

    2004-01-01

    Recent progress of low-energy antiproton physics by atomic spectroscopy and collisions using slow antiprotons collaboration at CERN AD is presented. High-precision spectroscopy of antiprotonic helium - a neutral three-body system pe**-He**2**+(=pHe**+) produced when antiprotons (p) are stopped in various phases of helium - has tested 3-body QED theories as well as proton-vs-antiproton CPT to within similar to 10**-**8. This was achieved by using a newly- developed radiofrequency quadrupole decelerator. Other ongoing and future experiments using low-energy antiprotons are discussed.

  4. Antiproton Accumulator (AA)

    CERN Multimedia

    Photographic Service

    1980-01-01

    The AA in its final stage of construction, before it disappeared from view under concrete shielding. Antiprotons were first injected, stochastically cooled and accumulated in July 1980. From 1981 on, the AA provided antiprotons for collisions with protons, first in the ISR, then in the SPS Collider. From 1983 on, it also sent antiprotons, via the PS, to the Low-Energy Antiproton Ring (LEAR). The AA was dismantled in 1997 and shipped to Japan.

  5. Antiproton physics at BNL

    Energy Technology Data Exchange (ETDEWEB)

    Lazarus, D.M. (Brookhaven National Lab., Upton, NY (United States))

    1993-06-07

    A review of antiproton physics at the Brookhaven AGS in past decade is given as well as a description of the present high energy physics program. Existing and potential facilities for antiproton physics at the AGS are discussed and are found to provide useful antiproton intensities over the momentum range proposed for SUPERLEAR in a multiple user environment. (orig.)

  6. The antiproton decelerator: AD

    International Nuclear Information System (INIS)

    Baird, S.; Berlin, D.; Boillot, J.; Bosser, J.; Brouet, M.; Buttkus, J.; Caspers, F.; Chohan, V.; Dekkers, D.; Eriksson, T.; Garoby, R.; Giannini, R.; Grobner, O.; Gruber, J.; Hemery, J.Y.; Koziol, H.; Maccaferri, R.; Maury, S.; Metzger, C.; Metzmacher, K.; Moehl, D.; Mulder, H.; Paoluzzi, M.; Pedersen, F.; Riunaud, J.P.; Serre, C.; Simon, D.J.; Tranquille, G.; Tuyn, J.; Williams, B.

    1997-01-01

    In view of a possible future programme of physics with low-energy antiprotons, a simplified scheme for the provision of antiprotons at 100 MeV/c has been studied. It uses the present target area and the modified antiproton collector (AC) in its present location. In this report the modifications and the operation are discussed. (orig.)

  7. Antiprotons get biological

    CERN Multimedia

    2003-01-01

    After its final run in September, the first results of the Antiproton Cell Experiment (ACE) look very promising. It was the first experiment to take data on the biological effects of antiproton beams to evaluate the potential of antiprotons in radiation therapy.

  8. Nuclear Excitations by Antiprotons and Antiprotonic Atoms

    CERN Multimedia

    2002-01-01

    The proposal aims at the investigation of nuclear excitations following the absorption and annihilation of stopped antiprotons in heavier nuclei and at the same time at the study of the properties of antiprotonic atoms. The experimental arrangement will consist of a scintillation counter telescope for the low momentum antiproton beam from LEAR, a beam degrader, a pion multiplicity counter, a monoisotopic target and Ge detectors for radiation and charged particles. The data are stored by an on-line computer.\\\\ \\\\ The Ge detectors register antiprotonic x-rays and nuclear @g-rays which are used to identify the residual nucleus and its excitation and spin state. Coincidences between the two detectors will indicate from which quantum state the antiprotons are absorbed and to which nuclear states the various reactions are leading. The measured pion multiplicity characterizes the annihilation process. Ge&hyphn. and Si-telescopes identify charged particles and determine their energies.\\\\ \\\\ The experiment will gi...

  9. Weighing the antiproton

    Energy Technology Data Exchange (ETDEWEB)

    Hayano, Ryugo S., E-mail: hayano@phys.s.u-tokyo.ac.jp [University of Tokyo, Department of Physics (Japan)

    2013-03-15

    Antiprotonic helium is a metastable three-body neutral atom consisting of an antiproton, a helium nucleus and an electron, which we serendipitously discovered some 20 years ago. The antiproton, which normally annihilates within a few picoseconds when injected into matter, can be 'stored' in this system for up to several microseconds, and laser spectroscopy is possible within this time window. From the laser transition frequency, the antiproton-to-electron mass ratio can be deduced to high precision. Recent progress at CERN's antiproton decelerator (AD) will be discussed.

  10. Frequency of unstable chromosome aberrations in peripheral lymphocytes of women with breast cancer treated with radiotherapy

    International Nuclear Information System (INIS)

    Espinoza Jeria, Marcela; Castro Acuna, Daniel

    2003-01-01

    This study proposes to obtain information about the behavior of the frequency and distribution of radiation induced lymphocyte dicentric chromosome aberrations with therapeutic doses in women with breast cancer treated only with radiotherapy, about which there are no existing works in Chile. Blood samples were taken from 6 women volunteers included in the study, with their informed consent, treated in the Fundacion Arturo Lopez Perez, aged 24 to 65 years old, without prior or parallel chemotherapy, nor prior radiotherapy. Three peripheral blood samples were taken from each patient in 0, 16.2 and 43.2 Gy doses. The lymphocytes obtained from each sample were cultivated using the micro-culture technique following the protocol in IAEA Technical Report No. 405, 2001. The samples were evaluated under a microscope and the unstable chromosome aberrations for lymphocytes were counted. A total of 500 cells per sample was evaluated in most cases, which were distributed depending on the number of aberrations that they had. The results were analyzed by treatment dose for each of the study patients, using the Papworth u test, Dolphin's 'Contaminated Poisson' method and Sasaki's 'QDR'. Great variations were observed in the frequency distribution of aberrations among the patients studied, which could be due to the influence of factors related to the patients' partial irradiations (C.Wood)

  11. ASACUSA hits antiproton jackpot

    CERN Multimedia

    2001-01-01

    The Japanese-European ASACUSA collaboration, which takes its name from the oldest district of Tokyo, approaches the antimatter enigma in a different way from the other two AD experiments, by inserting antiprotons into ordinary atoms. Last month the collaboration succeeded in trapping about a million antiprotons. The ASACUSA antiproton trap (lower cylinder), surmounted by its liquid helium reservoir. Looking on are Ken Yoshiki-Franzen, Zhigang Wang, Takahito Tasaki, Suzanne Reed, John Eades, Masaki Hori, Yasunori Yamazaki, Naofumi Kuroda, Jun Sakaguchi, Berti Juhasz, Eberhard Widmann and Ryu Hayano. A key element of the ASACUSA apparatus is its decelerating Radiofrequency Quadrupole magnet, RFQD. After tests with protons in Aarhus, this was installed in ASACUSA's antiproton beam last October (Bulletin 41/2000, 9 October 2000). Constructed by Werner Pirkl's group in PS Division, the RFQD works by applying an electric field to the AD antiproton pulse the opposite direction to its motion. As the antiprotons slo...

  12. Antiproton Cancer Therapy

    DEFF Research Database (Denmark)

    Bassler, Niels

    . The stopping power of high-energetic antiprotons in tissue, is similar to that of protons. Most energy is lost per unit distance as the particle comes to rest, but when the antiprotons stops, each one will annihilate on a nuclei, releasing 1.9 GeV of energy. Most of this energy is carried away by pions, gamma...... rays and neutrons, but a part of the annihilation energy is still deposited locally as recoiling nuclear fragments with limited range. These fragments will also increase the relative biological effect at the annihilation vertex. We have masured the biological effect of an antiproton beam for the first...... to handle antiprotons. This will enable us to do treatment planning with antiprotons, and thereby bring us closer to answer the question of the potential clinical benefit of antiprotons....

  13. The CERN antiproton collector

    International Nuclear Information System (INIS)

    Autin, B.

    1984-01-01

    The Antiproton Collector is a new ring of much larger acceptance than the present accumulator. It is designed to receive 10 8 antiprotons per PS cycle. In order to be compatible with the Antiproton Accumulator, the momentum spread and the emittances are reduced from 6% to 0.2% and from 200 π mm mrad to 25 π mm mrad respectively. In addition to the ring itself, the new target area and the modifications to the stochastic systems of the Antiproton Accumulator are described. (orig.)

  14. Investigations on the influence of radiotherapy on the extent of DNA-repair in peripheral lymphocytes and tumor cells of patients with cancer

    International Nuclear Information System (INIS)

    Klein, W.; Koren, H.; Alth, G.; Klein, H.

    1977-02-01

    The influence of radiotherapy on DNA excision repair after setting UV-lesions in peripheral lymphocytes and tumor cells of 11 patients with different forms of cancer was investigated. The effect of short term radiotherapy was compared with that after irradiation over a longer period. Radiotherapy provoked inhibition of DNA repair in tumor cells in every case, whereas changes in lymphocytes were dependent on irradiation schedule. (author)

  15. CERN: Antiprotons resist annihilation

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    Ask any particle physicist what is the eventual fate of an antiproton in matter and he will likely tell you that It annihilates'. True as this answer is, it hides a number of fascinating questions about the actual 'route' followed by the antiproton into the nucleus where it finally stops before annihilating with a nuclear particle

  16. LEAR: antiproton extraction lines

    CERN Multimedia

    Photographic Service

    1992-01-01

    Antiprotons, decelerated in LEAR to a momentum of 100 MeV/c (kinetic energy of 5.3 MeV), were delivered to the experiments in an "Ultra-Slow Extraction", dispensing some 1E9 antiprotons over times counted in hours. Beam-splitters and a multitude of beam-lines allowed several users to be supplied simultaneously.

  17. Lattices for antiproton rings

    International Nuclear Information System (INIS)

    Autin, B.

    1984-01-01

    After a description of the constraints imposed by the cooling of Antiprotons on the lattice of the rings, the reasons which motivate the shape and the structure of these machines are surveyed. Linear and non-linear beam optics properties are treated with a special amplification to the Antiproton Accumulator. (orig.)

  18. Searching for antiproton decay at the Fermilab Antiproton Accumulator

    International Nuclear Information System (INIS)

    Geer, S.

    1995-09-01

    This paper describes an experimental search for antiproton decay at the Fermilab Antiproton Accumulator. The E868 (APEX) experimental setup is described. The APEX data is expected to be sensitive to antiproton decay if the antiproton lifetimes is less than a few times 100,000 years

  19. Influence of radiotherapy on CD4+ CD25high regulatory cells in peripheral blood of NPC patients

    International Nuclear Information System (INIS)

    Liu Li; Ding Qian; Song Yingqiu; Cao Rubo; Yao Junxia; Huang Shiang

    2006-01-01

    Objective: The current study was designed to investigate the changes in peripheral CD4 + CD25 high regulatory T (CD4 + CD25 high Tr) cells in patients with nasopharyngeal carcinoma (NPC) and the influence of radiotherapy on immunity function. Methods: The peripheral blood was collected from 36 patients with NPC and 30 healthy controls. By using monoclonal antibodies, the blood samples were evaluated with flow cytometry for lymphocyte subsets and Tr cells. Results: The ratio of CD4 + /CD8 + in the NPC group was not significantly less than that in the healthy controls (P>0.05), but the prevalence of the CD4 + CD25 high Tr cells was significantly higher than that of the healthy group [(2.76 ± 1.06)% versus (2.06 ± 0.98)%, P + CD25 high Tr cells was higher than before it [(4.88 ± 1.02)%, P + CD25 high Tr cells in peripheral blood of NPC patients with or without radiotherapy was significantly higher than those in healthy controls, which may be related to immunosupression and tumor progression in such patients. This finding suggests that CD4 + CD25 high Tr cells in peripheral blood of NPC patients can be a useful index for monitoring the immunity function. (authors)

  20. SU-E-T-43: Analytical Model for Photon Peripheral Dose in Radiotherapy Treatments

    Energy Technology Data Exchange (ETDEWEB)

    Nieto, B Sanchez; El far, R [Instituto de Fisica, Pontificia Universidad Catolica de Chile, Santiago, Santiago De Chile (Chile); Romero-Exposito, M [Universitat Autonoma de Barcelona, Barcelona (Spain); Lagares, J [Centro de Investigaciones Energeticas Medioambientales y Tecnologicas, Madrid (Spain); Mateo, JC [Hospital Duques del Infantado, Sevilla (Spain); Terron, JA [Servicio de Radiofisica, Hospital Universitario Virgen Macarena, Sevilla (Spain); Irazola, L; Sanchez-Doblado, F [Servicio de Radiofisica, Hospital Universitario Virgen Macarena, Sevilla (Spain); Departamento de Fisiologia Medica y Biofisica, Universidad de Sevilla, Sevilla (Spain)

    2014-06-01

    Purpose: The higher survival rate of radiotherapy patients entails a growing concern on second cancers associated to peripheral doses. Currently, dosimetry of out-of field doses is still under development. Our group has developed a methodology to estimate neutron equivalent dose in organs (1,2). We aimed to propose a model to estimate out-of-field photon doses in isocentric treatments from basic clinical data. Methods: The proposed function models the dose as the sum of leakage and scatter terms. The latter is modeled as a virtual source at the collimator, which suffers from attenuation in air and tissue, corrected by the inverse-square-law. The model was parameterized using experimental measurements with TLD700 chips placed inside an anthropomorphic phantom (6–18MV) irradiated with conformal and modulated techniques in Elekta, Siemens and Varian linacs. This model provides photon dose at a point as a function of clinical parameters as prescription dose/UM, PTV volume, distance to the field edge, height of the MLC leaves and distance from the the MLC to the isocenter. Model was tested against independent measurements (TLD100) for a VMAT treatment on a Elekta. Dose to organs is modeled from dose to points along the head-to-feet axis of the organ of a “standard man” escalated by patient height. Results: Our semi-empirical model depends on 3 given parameters (leakage parameter can be individualized). A novelty of our model, over other models (e.g., PERIDOSE), arises from its applicability to any technique (independently of the number of MU needed to deliver a dose). Differences between predictions and measurements were < 0.005mSv/UM. Conclusion: We have proposed a unique model which successfully account for photon peripheral organ dose. This model can be applied in the day-to-day clinic as it only needs a few basic parameters which are readily accessible.1. Radiother. Oncol. 107:234–243, 2013. 2. Phys. Med. Biol. 57:6167–6191, 2012.

  1. SU-E-T-43: Analytical Model for Photon Peripheral Dose in Radiotherapy Treatments

    International Nuclear Information System (INIS)

    Nieto, B Sanchez; El far, R; Romero-Exposito, M; Lagares, J; Mateo, JC; Terron, JA; Irazola, L; Sanchez-Doblado, F

    2014-01-01

    Purpose: The higher survival rate of radiotherapy patients entails a growing concern on second cancers associated to peripheral doses. Currently, dosimetry of out-of field doses is still under development. Our group has developed a methodology to estimate neutron equivalent dose in organs (1,2). We aimed to propose a model to estimate out-of-field photon doses in isocentric treatments from basic clinical data. Methods: The proposed function models the dose as the sum of leakage and scatter terms. The latter is modeled as a virtual source at the collimator, which suffers from attenuation in air and tissue, corrected by the inverse-square-law. The model was parameterized using experimental measurements with TLD700 chips placed inside an anthropomorphic phantom (6–18MV) irradiated with conformal and modulated techniques in Elekta, Siemens and Varian linacs. This model provides photon dose at a point as a function of clinical parameters as prescription dose/UM, PTV volume, distance to the field edge, height of the MLC leaves and distance from the the MLC to the isocenter. Model was tested against independent measurements (TLD100) for a VMAT treatment on a Elekta. Dose to organs is modeled from dose to points along the head-to-feet axis of the organ of a “standard man” escalated by patient height. Results: Our semi-empirical model depends on 3 given parameters (leakage parameter can be individualized). A novelty of our model, over other models (e.g., PERIDOSE), arises from its applicability to any technique (independently of the number of MU needed to deliver a dose). Differences between predictions and measurements were < 0.005mSv/UM. Conclusion: We have proposed a unique model which successfully account for photon peripheral organ dose. This model can be applied in the day-to-day clinic as it only needs a few basic parameters which are readily accessible.1. Radiother. Oncol. 107:234–243, 2013. 2. Phys. Med. Biol. 57:6167–6191, 2012

  2. New Experiments with Antiprotons

    Science.gov (United States)

    Kaplan, D. M.

    2011-12-01

    Fermilab operates the world's most intense antiproton source. Recently proposed experiments can use those antiprotons either parasitically during Teva-tron Collider running or after the Tevatron Collider finishes in about 2011. For example, the annihilation of 8 GeV antiprotons might make the world's most intense source of tagged D0 mesons, and thus the best near-term opportunity to study charm mixing and search for new physics via its CP-violation signature. Other possible precision measurements include properties of the X(3872) and the charmonium system. An experiment using a Penning trap and an atom interferometer could make the world's first measurement of the gravitational force on antimatter. These and other potential measurements using antiprotons could yield a broad physics program at Fermilab in the post-Tevatron era.

  3. Perspectives for polarized antiprotons

    International Nuclear Information System (INIS)

    Lenisa, Paolo

    2012-01-01

    Polarized antiprotons would open a new window in hadron physics providing access to a wealth of single and double spin observables in proton-antiproton interactions. The PAX Collaboration aims to perform the first ever measurement of the spin-dependence of the proton-antiproton cross section at the AD ring at CERN. The spin-dependence of the cross section could in principle be exploited by the spin-filtering technique for the production of a polarized antiproton beam. As a preparatory phase to the experimentation at AD, the PAX Collaboration has initiated a series of dedicated studies with protons at the COSY-ring in Juelich (Germany), aimed at the commissioning of the experimental apparatus and confirmation of the predictions for spin-filtering with protons.

  4. Antiprotonic-hydrogen atoms

    International Nuclear Information System (INIS)

    Batty, C.J.

    1989-07-01

    Experimental studies of antiprotonic-hydrogen atoms have recently made great progress following the commissioning of the low energy antiproton facility (LEAR) at CERN in 1983. At the same time our understanding of the atomic cascade has increased considerably through measurements of the X-ray spectra. The life history of the p-bar-p atom is considered in some detail, from the initial capture of the antiproton when stopping in hydrogen, through the atomic cascade with the emission of X-rays, to the final antiproton annihilation and production of mesons. The experiments carried out at LEAR are described and the results compared with atomic cascade calculations and predictions of strong interaction effects. (author)

  5. Radiotherapy

    International Nuclear Information System (INIS)

    Prosnitz, L.R.; Kapp, D.S.; Weissberg, J.B.

    1983-01-01

    This review highlights developments over the past decade in radiotherapy and attempts to summarize the state of the art in the management of the major diseases in which radiotherapy has a meaningful role. The equipment, radiobiology of radiotherapy and carcinoma of the lung, breast and intestines are highlighted

  6. Chromosomal aberration in peripheral lymphocytes and doses to the active bone marrow in radiotherapy of prostate cancer

    International Nuclear Information System (INIS)

    Gershkevitsh, E.; Trott, K.R.

    2002-01-01

    Purpose: Radiotherapy plays an important role in the management of prostate cancer. Epidemiological data indicate a small but significant risk of radiation-induced leukemia after radiotherapy which might be related to the high mean bone marrow dose associated with radiotherapy of prostate cancer. The purpose of the study was to investigate the relation between the mean bone marrow dose and unstable chromosome aberrations in peripheral blood lymphocytes in patients undergoing conformal radiotherapy for prostate cancer as a possible indicator of risk. Endometrial cancer patients were also included for comparison. Patients and Methods: Nine patients, six with prostate cancer (60-73 years old) and three with endometrial cancer (61-81 years old) treated with radiotherapy were included in the study. The non-bony spaces inside the pelvic bones were outlined on every CT slice using the treatment planning system and mean doses to the bone marrow calculated. Blood samples of the patients were obtained at different times before, during and at the end of treatment. Lymphocytes were cultured in the usual way and metaphases scored for dicentric aberrations. Results: 46 samples from nine patients were obtained. The mean number of metaphases analyzed per sample was 180 with a range from 52 to 435. The mean bone marrow doses for prostate cancer patients ranged from 2.8 to 4.2 Gy and for endometrial cancer patients from 12.8 to 14.8 Gy. The aberration yield increased with the planning target volume and the mean bone marrow dose. Conclusion: The yield of dicentric aberrations for prostate cancer patients correlated closely with the mean bone marrow dose albeit the induction of dicentrics occurred in mature T lymphocytes most of which were probably in transit through the irradiated volumes. Therefore, the observed relationship between dicentrics and mean bone marrow doses are indirect. (orig.) [de

  7. Effect of fractionated regional external beam radiotherapy on peripheral blood cell count

    International Nuclear Information System (INIS)

    Zachariah, B.; Jacob, S.S.; Gwede, C.; Cantor, A.; Patil, J.; Casey, L.; Zachariah, A.B.

    2001-01-01

    Purpose: The purpose of this study was to assess the need for obtaining weekly complete blood count (CBC) values and to identify the pattern of changes in CBC during regional conventional fractionated radiotherapy. Methods and Materials: A retrospective analysis of CBC data on 299 adult cancer patients who received definitive conventional radiotherapy to head and neck (n=95), chest (n=96), and pelvis (n=108) was performed. Temporal patterns and magnitude of change in white blood cells, neutrophils, lymphocytes, and platelets during radiotherapy were examined. Results: There were statistically significant declines in all counts, albeit not clinically significant. Notable differences between disease sites were found. The greatest weekly interval change in counts occurred during the first week of radiotherapy for all groups of patients. The mean WBC nadir values during treatment were 5.8 for head and neck, 6.8 for chest, and 5.4 for pelvis. The nadirs for all counts occurred toward the middle-to-end of radiotherapy. Lymphocytes were found to be more sensitive to radiotherapy than other leukocyte subcomponents. Conclusion: Our study suggests that weekly CBC monitoring is not necessary for all patients undergoing standard fractionated radiotherapy. Baseline blood counts may be used to determine an optimal schedule for monitoring CBCs in patients receiving conventional radiation alone. Reduced monitoring of CBC may result in significant financial savings

  8. Effect of image-guided hypofractionated stereotactic radiotherapy on peripheral non-small-cell lung cancer

    Directory of Open Access Journals (Sweden)

    Wang SW

    2016-08-01

    Full Text Available Shu-wen Wang,1 Juan Ren,1 Yan-li Yan,2 Chao-fan Xue,2 Li Tan,2 Xiao-wei Ma2 1Department of Radiotherapy, First Affiliated Hospital of Xian Jiaotong University, 2Medical School of Xian Jiaotong University, Xi’an, Shaanxi, People’s Republic of China Abstract: The objective of this study was to compare the effects of image-guided hypofractionated radiotherapy and conventional fractionated radiotherapy on non-small-cell lung cancer (NSCLC. Fifty stage- and age-matched cases with NSCLC were randomly divided into two groups (A and B. There were 23 cases in group A and 27 cases in group B. Image-guided radiotherapy (IGRT and stereotactic radiotherapy were conjugately applied to the patients in group A. Group A patients underwent hypofractionated radiotherapy (6–8 Gy/time three times per week, with a total dose of 64–66 Gy; group B received conventional fractionated radiotherapy, with a total dose of 68–70 Gy five times per week. In group A, 1-year and 2-year local failure survival rate and 1-year local failure-free survival rate were significantly higher than in group B (P<0.05. The local failure rate (P<0.05 and distant metastasis rate (P>0.05 were lower in group A than in group B. The overall survival rate of group A was significantly higher than that of group B (P=0.03, and the survival rate at 1 year was 87% vs 63%, (P<0.05. The median survival time of group A was longer than that of group B. There was no significant difference in the incidence of complications between the two groups (P>0.05. Compared with conventional fractionated radiation therapy, image-guided hypofractionated stereotactic radiotherapy in NSCLC received better treatment efficacy and showed good tolerability. Keywords: non-small-cell lung cancer, hypofractionated radiotherapy, stereotactic radiotherapy, segmentation, intensity-modulated radiotherapy, image-guided radiation therapy technology

  9. Study of alleviation of peripheral circulation disturbance due to surgery and radiotherapy, 1

    International Nuclear Information System (INIS)

    Tedo, Tohru; Ohnuma, Isao; Hino, Shigeki; Kanetomo, Takafumi

    1979-01-01

    133 Xe-clearance in the branium was measured in order to detect circulatory disturbance following surgery and during and after radiotherapy for breast cancer. In 5 of 10 cases (50%) in which surgery and radiotherapy were performed for breast cancer, lowered circulatory function was noted in the affected side. Lowered function was seen in the non-affected side of the 10 cases in 3 (30%), and normal function was observed in 2 (20%). In 4 of 13 cases (75%), including 3 cases in which radiotherapy was performed, many subjective symptoms were noted. Circulatory function was lowered in 3 of the 4 cases. Generally, cases involving many subjective symptoms were of lowered circulatory function. In the cases in which lowered circulatory function was noted in the non-affected side, there were no subjective symptoms. In all the cases in which radiotherapy was continued or in which radiotherapy had almost been completed, a more or less lowered circulatory function was noted. The onset of lowered function and whether surgery or radiotherapy lowered circulation are unknown. (Ueda, J.)

  10. Haralick textural features on T2 -weighted MRI are associated with biochemical recurrence following radiotherapy for peripheral zone prostate cancer.

    Science.gov (United States)

    Gnep, Khémara; Fargeas, Auréline; Gutiérrez-Carvajal, Ricardo E; Commandeur, Frédéric; Mathieu, Romain; Ospina, Juan D; Rolland, Yan; Rohou, Tanguy; Vincendeau, Sébastien; Hatt, Mathieu; Acosta, Oscar; de Crevoisier, Renaud

    2017-01-01

    To explore the association between magnetic resonance imaging (MRI), including Haralick textural features, and biochemical recurrence following prostate cancer radiotherapy. In all, 74 patients with peripheral zone localized prostate adenocarcinoma underwent pretreatment 3.0T MRI before external beam radiotherapy. Median follow-up of 47 months revealed 11 patients with biochemical recurrence. Prostate tumors were segmented on T 2 -weighted sequences (T 2 -w) and contours were propagated onto the coregistered apparent diffusion coefficient (ADC) images. We extracted 140 image features from normalized T 2 -w and ADC images corresponding to first-order (n = 6), gradient-based (n = 4), and second-order Haralick textural features (n = 130). Four geometrical features (tumor diameter, perimeter, area, and volume) were also computed. Correlations between Gleason score and MRI features were assessed. Cox regression analysis and random survival forests (RSF) were performed to assess the association between MRI features and biochemical recurrence. Three T 2 -w and one ADC Haralick textural features were significantly correlated with Gleason score (P recurrence (P recurrence following prostate cancer radiotherapy. 3 J. Magn. Reson. Imaging 2017;45:103-117. © 2016 International Society for Magnetic Resonance in Medicine.

  11. Radiotherapy

    Directory of Open Access Journals (Sweden)

    Rema Jyothirmayi

    1999-01-01

    Full Text Available Purpose. Conservative treatment in the form of limited surgery and post-operative radiotherapy is controversial in hand and foot sarcomas, both due to poor radiation tolerance of the palm and sole, and due to technical difficulties in achieving adequate margins.This paper describes the local control and survival of 41 patients with soft tissue sarcoma of the hand or foot treated with conservative surgery and radiotherapy. The acute and late toxicity of megavoltage radiotherapy to the hand and foot are described. The technical issues and details of treatment delivery are discussed. The factors influencing local control after radiotherapy are analysed.

  12. FERMILAB: More antiprotons

    International Nuclear Information System (INIS)

    Visnjic, Vladimir

    1993-01-01

    The excellent performance of the Fermilab antiproton complex during the recent Collider run and its future potential are the cumulative result of many improvements over the past few years, ranging from major projects like upgrading the stack-tail stochastic cooling system in the Accumulator to minor improvements like automating tuning procedures. The antiprotons are created when the 120 GeV proton beam from the Main Ring hits the target. A good target should have high yield of antiprotons, should not melt, and should not crack due to shock waves. The old copper target has been replaced by a new one made of nickel. The yield into the Debuncher is 2 x 10 -5 antiprotons/proton. While this is only marginally better than for copper, the nickel target has high melting point energy (1070 J/g) and a low rate of increase in pressure with deposited energy, making it the target of choice for the proton intensities expected in the Main Injector era (June, page 10). Of the broad spectrum of all kinds of secondaries, only a tiny fraction are 8 GeV antiprotons. The 8 GeV negative charge secondaries are bent through 3° by a new pulsed magnet. Instead of a 200-turn magnet with coils separated by epoxy as in the past, the new magnet has one turn carrying 45.5 kA of current. This single turn pulsed magnet uses radiation hard ceramic and is much more robust

  13. Peripheral dose measurement in high-energy photon radiotherapy with the implementation of MOSFET.

    Science.gov (United States)

    Vlachopoulou, Vassiliki; Malatara, Georgia; Delis, Harry; Theodorou, Kiki; Kardamakis, Dimitrios; Panayiotakis, George

    2010-11-28

    To study the peripheral dose (PD) from high-energy photon beams in radiotherapy using the metal oxide semiconductor field effect transistor (MOSFET) dose verification system. The radiation dose absorbed by the MOSFET detector was calculated taking into account the manufacturer's Correction Factor, the Calibration Factor and the threshold voltage shift. PD measurements were carried out for three different field sizes (5 cm × 5 cm, 10 cm × 10 cm and 15 cm × 15 cm) and for various depths with the source to surface distance set at 100 cm. Dose measurements were realized on the central axis and then at distances (1 to 18 cm) parallel to the edge of the field, and were expressed as the percentage PD (% PD) with respect to the maximum dose (d(max)). The accuracy of the results was evaluated with respect to a calibrated 0.3 cm(3) ionization chamber. The reproducibility was expressed in terms of standard deviation (s) and coefficient of variation. % PD is higher near the phantom surface and drops to a minimum at the depth of d(max), and then tends to become constant with depth. Internal scatter radiation is the predominant source of PD and the depth dependence is determined by the attenuation of the primary photons. Closer to the field edge, where internal scatter from the phantom dominates, the % PD increases with depth because the ratio of the scatter to primary increases with depth. A few centimeters away from the field, where collimator scatter and leakage dominate, the % PD decreases with depth, due to attenuation by the water. The % PD decreases almost exponentially with the increase of distance from the field edge. The decrease of the % PD is more than 60% and can reach up to 90% as the measurement point departs from the edge of the field. For a given distance, the % PD is significantly higher for larger field sizes, due to the increase of the scattering volume. Finally, the measured PD obtained with MOSFET is higher than that obtained with an ionization chamber

  14. Biological Effectiveness of Antiproton Annihilation

    DEFF Research Database (Denmark)

    Maggiore, C.; Agazaryan, N.; Bassler, N.

    2004-01-01

    from the annihilation of antiprotons produce an increase in ‘‘biological dose’’ in the vicinity of the narrow Bragg peak for antiprotons compared to protons. This experiment is the first direct measurement of the biological effects of antiproton annihilation. The background, description, and status...

  15. Interaction of antiprotons with nuclei

    Czech Academy of Sciences Publication Activity Database

    Hrtánková, Jaroslava; Mareš, Jiří

    2016-01-01

    Roč. 945, JAN (2016), s. 197-215 ISSN 0375-9474 R&D Projects: GA ČR(CZ) GA15-04301S Institutional support: RVO:61389005 Keywords : antiproton-nucleus interaction * antiproton annihilation * antiproton nuclear bound states Subject RIV: BE - Theoretical Physics Impact factor: 1.916, year: 2016

  16. The CERN antiproton programme

    International Nuclear Information System (INIS)

    Herr, H.

    1979-01-01

    A diagram and basic parameters of the ICE (Initial Cooling Experiment) storage ring constructed in CERN are examined. The experimental results of stochastic and electron cooling and the results of measuring of the antiproton lifetime are discussed. The main parameters of the antiproton storage are listed. Comparison between stochastic and electron cooling has shown that the latter is characterized by shorter cooling time independent of the particle number in a beam. Advantage of stochastic cooling lies in its possible usage at higher energies [ru

  17. Biological effectiveness of antiproton annihilation

    DEFF Research Database (Denmark)

    Holzscheiter, M.H.; Agazaryan, N.; Bassler, Niels

    2004-01-01

    We describe an experiment designed to determine whether or not the densely ionizing particles emanating from the annihilation of antiprotons produce an increase in ‘‘biological dose’’ in the vicinity of the narrow Bragg peak for antiprotons compared to protons. This experiment is the first direct...... measurement of the biological effects of antiproton annihilation. The experiment has been approved by the CERN Research Board for running at the CERN Antiproton Decelerator (AD) as AD-4/ACE (Antiproton Cell Experiment) and has begun data taking in June of 2003. The background, description and the current...

  18. Biological effectiveness of antiproton annihilation

    CERN Document Server

    Holzscheiter, Michael H.; Bassler, Niels; Beyer, Gerd; De Marco, John J.; Doser, Michael; Ichioka, Toshiyasu; Iwamoto, Keisuke S.; Knudsen, Helge V.; Landua, Rolf; Maggiore, Carl; McBride, William H.; Møller, Søren Pape; Petersen, Jorgen; Smathers, James B.; Skarsgard, Lloyd D.; Solberg, Timothy D.; Uggerhøj, Ulrik I.; Withers, H.Rodney; Vranjes, Sanja; Wong, Michelle; Wouters, Bradly G.

    2004-01-01

    We describe an experiment designed to determine whether or not the densely ionizing particles emanating from the annihilation of antiprotons produce an increase in “biological dose” in the vicinity of the narrow Bragg peak for antiprotons compared to protons. This experiment is the first direct measurement of the biological effects of antiproton annihilation. The experiment has been approved by the CERN Research Board for running at the CERN Antiproton Decelerator (AD) as AD-4/ACE (Antiproton Cell Experiment) and has begun data taking in June of 2003. The background, description and the current status of the experiment are given.

  19. Radiotherapy

    International Nuclear Information System (INIS)

    Zedgenidze, G.A.; Kulikov, V.A.; Mardynskij, Yu.S.

    1984-01-01

    The technique for roentgenotopometric and medicamentous preparation of patients for radiotherapy has been reported in detail. The features of planning and performing of remote, intracavitary and combined therapy in urinary bladder cancer are considered. The more effective methods of radiotherapy have been proposed taking into account own experience as well as literature data. The comparative evaluation of treatment results and prognosis are given. Radiation pathomorphism of tumors and tissues of urinary bladder is considered in detail. The problems of diagnosis, prophylaxis and treatment of complications following radiodiagnosis and radiotherapy in patients with urinary bladder cancer are illustrated widely

  20. Coincidence studies with antiprotons

    Energy Technology Data Exchange (ETDEWEB)

    McGovern, M; Walters, H R J [Department of Applied Mathematics and Theoretical Physics, Queen' s University, Belfast BT7 1NN (United Kingdom); Assafrao, D; Mohallem, J R [Laboratorio de Atomos e Moleculas Especiais, Departamento de Fisica, ICEx, Universidade Federal de Minas Gerais, P.O Box 702, 30123-970 Belo Horizonte, MG (Brazil); Whelan, Colm T, E-mail: mmcgovern06@qub.ac.u [Department of Physics, Old Dominion University, Norfolk, VA 23529-0116 (United States)

    2010-02-01

    We present a short overview of a new method for calculating fully differential cross sections that is able to describe any aspect of coincidence measurements involving heavy projectiles. The method is based upon impact parameter close coupling with pseudostates. Examples from antiproton impact ionization are shown.

  1. Progress in antiproton physics

    International Nuclear Information System (INIS)

    Miettinen, H.I.

    1976-09-01

    Some recent results on proton-antiproton collisions are reviewed. The duality structure of processes where baryon number or strangeness may be annihilated receives particular attention. Attempts to obtain experimental information on the impact parameter space structure of multiparticle processes are discussed. Suggestions for future research are made

  2. Antiprotons are another matter

    International Nuclear Information System (INIS)

    Hynes, M.V.

    1987-01-01

    Theories of gravity abound, whereas experiments in gravity are few in number. An important experiment in gravity that has not been performed is the measurement of the gravitational acceleration of antimatter. Although there have been attempts to infer these properties from those of normal matter, none of these theoretical arguments are compelling. Modern theories of gravity that attempt to unify gravity with the other forces of nature predict that in principle antimatter can fall differently than normal matter in the Earth's field. Some of these supergravity theories predict that antimatter will fall faster, and that normal matter will fall with a small Baryon-number dependance in the earth's field. All of these predictions violate the Weak Equivalence Principle, a cornerstone of General Relativity, but are consistent with CPT conservation. In our approved experiment at LEAR (PS-200) we will test the Weak Equivalence Principle for antimatter by measuring the gravitational acceleration of the antiproton. Through a series of deceleration stages, antiprotons from LEAR will be lowered in energy to ∼4 Kelvin at which energy the gravitational effect will be measureable. The measurement will employ the time-of-flight technique wherein the antiprotons are released vertically in a drift tube. The spectrum of time-of-flight measurements can be used to extract the gravitational acceleration experienced by the particles. The system will be calibrated using H - ions which simulates the electromagnetic behavior of the antiproton, yet is a baryon to ∼0.1%. To extract the gravitational acceleration of the antiproton relative to the H - ion with a statistical precision of 1% will require the release of ∼10 6 to 10 7 particles

  3. Antiprotons are another matter

    International Nuclear Information System (INIS)

    Hynes, M.V.

    1988-01-01

    Theories of gravity abound whereas experiments in gravity are few in number. An important experiment in gravity that has not been performed is the measurement of the gravitational acceleration of antimatter. Although there have been attempts to infer this property from those of normal matter, none of these theoretical arguments are compelling. Modern theories of gravity that attempt to unify gravity with the other forces of nature predict that in principle antimatter can fall differently than normal matter in the Earth's field. Some of these supergravity theories predict that antimatter will fall faster and that normal matter will fall with a small Baryon-number dependence in the Earth's field. All of these predictions violate the Weak Equivalence Principle, a cornerstone of General Relativity, but are consistent with CPT conservation. In our approved experiment at LEAR (PS-200) we will test the Weak Equivalence Principle for antimatter by measuring the gravitational acceleration of the antiproton. Through a series of deceleration stages, antiprotons from LEAR will be lowered in energy to ≅ 4 Kelvin at which energy the gravitational effect will be measureable. The measurement will employ the time-of-flight technique wherein the antiprotons are released vertically in a drift tube. The spectrum of time-of-flight measurements can be used to extract the gravitational acceleration experienced by the particles. The system will be calibrated using H - ions which simulate the electromagnetic behavior of the antiproton yet are baryons to ≅ 0.1%. To extract the gravitational acceleration of the antiproton relative to the H - ion with a statistical precision of 1% will require the release of ≅ 10 6 -10 7 particles. (orig.)

  4. Radiotherapy after high-dose chemotherapy and peripheral blood stem cell support in high-risk breast cancer

    International Nuclear Information System (INIS)

    Hoeller, Ulrike; Heide, Juergen; Kroeger, Nicolaus; Krueger, William; Jaenicke, Fritz; Alberti, Winfried

    2002-01-01

    Purpose: To assess the toxicity and efficacy of radiotherapy with respect to locoregional control after adjuvant high-dose chemotherapy for patients with breast cancer. At first, radiotherapy was withheld because of toxicity concerns, but it was introduced in 1995 because of reported high locoregional relapse rates. Methods and Materials: Between 1992 and 1998, 40 patients with Stage II-III high-risk breast cancer received adjuvant high-dose chemotherapy consisting of thiotepa, mitoxantrone, and cyclophosphamide and peripheral blood stem cell support after four cycles of induction chemotherapy. The chest wall or breast, as well as the supraclavicular nodes, were irradiated with electrons and photons to a median dose of 50.4 Gy in 20 patients. Six additional patients received only supraclavicular irradiation to a median dose of 50.4 Gy. Acute toxicity was scored clinically. Pulmonary function tests were performed in 14 irradiated patients before high-dose chemotherapy and 1.1-4.4 years (median 1.6) after irradiation. The median follow-up time of living patients was 33 vs. 67 months in irradiated (n=26) and nonirradiated (n=14) patients, respectively. Results: G2 and G3 hematologic toxicity occurred in 1 patient each. No clinical pneumonitis or clinical impairment of lung function was observed. After 1-2 years, the lung function tests showed only minor changes in 4 patients. The 3-year locoregional control rate was 92% in the irradiated patients vs. 58% in the nonirradiated patients (p=0.049, actuarial analysis). Conclusion: In this series, adjuvant radiotherapy after adjuvant chemotherapy for breast cancer appeared well tolerated, with improved local regional control and without significant side effects. Longer follow-up and more patient accrual, as well as Phase III trials, are necessary for confirmation

  5. Radiotherapy

    International Nuclear Information System (INIS)

    Wannenmacher, M.; Debus, J.; Wenz, F.

    2006-01-01

    The book is focussed on the actual knowledge on the clinical radiotherapy and radio-oncology. Besides fundamental and general contributions specific organ systems are treated in detail. The book contains the following contributions: Basic principles, radiobiological fundamentals, physical background, radiation pathology, basics and technique of brachytherapy, methodology and technique of the stereotactic radiosurgery, whole-body irradiation, operative radiotherapy, hadron therapy, hpyerthermia, combined radio-chemo-therapy, biometric clinical studies, intensity modulated radiotherapy, side effects, oncological diagnostics; central nervous system and sense organs, head-neck carcinomas, breast cancer, thorax organs, esophagus carcinoma, stomach carcinoma, pancreas carcinoma, heptabiliary cancer and liver metastases, rectal carcinomas, kidney and urinary tract, prostate carcinoma, testicular carcinoma, female pelvis, lymphatic system carcinomas, soft tissue carcinoma, skin cancer, bone metastases, pediatric tumors, nonmalignant diseases, emergency in radio-oncology, supporting therapy, palliative therapy

  6. Laser spectroscopy of antiprotonic helium

    CERN Document Server

    Hori, M

    2005-01-01

    When antiprotons (i.e. the antimatter counterpart of protons) are stopped in helium gas, 97% of them annihilate within picoseconds by reacting with the helium nuclei; a 3% fraction, however, survive with an anomalously long lifetime of several microseconds. This longevity is due to the formation of antiprotonic helium, which is a three-body Rydberg atom composed of an antiproton, electron, and helium nucleus. The ASACUSA experimental collaboration has recently synthesized large numbers of these atoms using CERN's Antiproton Decelerator facility, and measured the atom's transition frequencies to 60 parts per billion by laser spectroscopy. By comparing the experimental results with recent three-body QED calculations and the known antiproton cyclotron frequency, we were able to show that the antiproton mass and charge are the same as the corresponding proton values to a precision of 10 parts per billion. Ongoing and future series of experiments will further improve the experimental precision by using chirp-compe...

  7. Antiproton Radiation Therapy

    DEFF Research Database (Denmark)

    Bassler, Niels; Holzscheiter, Michael H.; Petersen, Jørgen B.B.

    2007-01-01

    the radiobiological properties using antiprotons at 50 and 125 MeV from the Antiproton Decelerator (AD) at CERN. Dosimetry experiments were carried out with ionization chambers, alanine pellets and radiochromic film. Radiobiological experiments were done with Chinese V79 WNRE hamster cells. Monte Carlo particle...... transport codes were investigated and compared with results obtained from the ionization chambers and alanine pellets. A track structure model have been applied on the calculated particle spectrum, and been used to predict the LET-dependent response of the alanine pellets. The particle transport program...... FLUKA produced data which were in excellent agreement with our ionization chamber measurements, and in good agreement with our alanine measurements. FLUKA is now being used to generate a wide range of depth dose data at several energies, including secondary particle–energy spectra, which will be used...

  8. On the antiproton discovery

    International Nuclear Information System (INIS)

    Piccioni, O.

    1989-01-01

    The author of this article describes his own role in the discovery of the antiproton. Although Segre and Chamberlain received the Nobel Prize in 1959 for its discovery, the author claims that their experimental method was his idea which he communicated to them informally in December 1954. He describes how his application for citizenship (he was Italian), and other scientists' manipulation, prevented him from being at Berkeley to work on the experiment himself. (UK)

  9. Bubble chamber: antiproton annihilation

    CERN Multimedia

    1971-01-01

    These images show real particle tracks from the annihilation of an antiproton in the 80 cm Saclay liquid hydrogen bubble chamber. A negative kaon and a neutral kaon are produced in this process, as well as a positive pion. The invention of bubble chambers in 1952 revolutionized the field of particle physics, allowing real tracks left by particles to be seen and photographed by expanding liquid that had been heated to boiling point.

  10. ALPHA freezes antiprotons

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    Laboratories like CERN can routinely produce many different types of antiparticles. In 1995, the PS210 experiment formed the first antihydrogen atoms and a few years later, in 2002, ATRAP and ATHENA were already able to produce several thousand of them. However, no experiment in the world has succeeded in ‘trapping’ these anti-atoms in order to study them. This is the goal of the ALPHA experiment, which has recently managed to cool down the antiprotons to just a few Kelvin. This represents a major step towards trapping the anti-atom, thus opening a new avenue into the investigation of antimatter properties.   Members of the ALPHA collaboration working on the apparatus in the Antiproton Decelerator experimental hall at CERN. Just like the atom, the anti-atom is neutral. Unlike the atom, the anti-atom is made up of antiprotons (as opposed to protons in the atom) and positrons (as opposed to electrons). In order to thoroughly study the properties of the anti-atoms, scien...

  11. Extra Low ENergy Antiproton

    CERN Multimedia

    To produce dense antiproton beams at very low energies (110 keV), it has been proposed to install a small decelerator ring between the existing AD ring and the experimental area. Phase-space blowup during deceleration is compensated by electron cooling such that the final emittances are comparable to the 5MeV beam presently delivered by the AD. An immediate consequence is a significant increase in the number of trapped antiprotons at the experiments as outlined in the proposal CERN/SPSC-2009-026; SPCS-P-338. This report describes the machine parameters and layout of the proposal ELENA (Extra Low ENergy Antiproton)ring also gives an approximate estimate of cost and manpower needs. Since the initial estimate, published in 2007 (CERN-AB-2007-079), the ELENA design has evolved considerably. This is due to a new location in the AD hall to acommodate for the possibility of another experimental zone, as suggested by the SPCS, and also due to improvements in the ring optics and layout. The cost estimate that is prese...

  12. Antiproton compression and radial measurements

    CERN Document Server

    Andresen, G B; Bowe, P D; Bray, C C; Butler, E; Cesar, C L; Chapman, S; Charlton, M; Fajans, J; Fujiwara, M C; Funakoshi, R; Gill, D R; Hangst, J S; Hardy, W N; Hayano, R S; Hayden, M E; Humphries, A J; Hydomako, R; Jenkins, M J; Jorgensen, L V; Kurchaninov, L; Lambo, R; Madsen, N; Nolan, P; Olchanski, K; Olin, A; Page R D; Povilus, A; Pusa, P; Robicheaux, F; Sarid, E; Seif El Nasr, S; Silveira, D M; Storey, J W; Thompson, R I; Van der Werf, D P; Wurtele, J S; Yamazaki, Y

    2008-01-01

    Control of the radial profile of trapped antiproton clouds is critical to trapping antihydrogen. We report detailed measurements of the radial manipulation of antiproton clouds, including areal density compressions by factors as large as ten, achieved by manipulating spatially overlapped electron plasmas. We show detailed measurements of the near-axis antiproton radial profile, and its relation to that of the electron plasma. We also measure the outer radial profile by ejecting antiprotons to the trap wall using an octupole magnet.

  13. Calculated LET spectrum from antiproton beams stopping in water

    CERN Document Server

    Bassler, Niels

    2009-01-01

    Antiprotons have been proposed as a potential modality for radiotherapy because the annihilation at the end of range leads to roughly a doubling of physical dose in the Bragg peak region. So far it has been anticipated that the radiobiology of antiproton beams is similar to that of protons in the entry region of the beam, but very different in the annihilation region, due to the expected high-LET components resulting from the annihilation. On closer inspection we find that calculations of dose averaged LET in the entry region may suggest that the RBE of antiprotons in the plateau region could significantly differ from unity, which seems to warrant closer inspection of the radiobiology in this region. Materials and Methods. Monte Carlo simulations using FLUKA were performed for calculating the entire particle spectrum of a beam of 126 MeV antiprotons hitting a water phantom. Results and Discussion. In the plateau region of the simulated antiproton beam we observe a dose-averaged unrestrict...

  14. Evaluation of the peripheral dose in stereotactic radiotherapy and radiosurgery treatments

    Energy Technology Data Exchange (ETDEWEB)

    Di Betta, Erika; Fariselli, Laura; Bergantin, Achille; Locatelli, Federica; Del Vecchio, Antonella; Broggi, Sara; Fumagalli, Maria Luisa [Department of Neurosurgery, Division of Medical Physics, Fondazione IRCCS, Istituto Neurologico C. Besta, 20133 Milano (Italy); Department of Neurosurgery, Division of Radiotherapy, Fondazione IRCCS, Istituto Neurologico C. Besta, 20133 Milano (Italy); CyberKnife Centre, Centro Diagnostico Italiano, 20147 Milano (Italy); Division of Medical Physics, Fondazione IRCCS, Istituto S. Raffaele, 20132 Milano (Italy); Department of Neurosurgery, Division of Medical Physics, Fondazione IRCCS, Istituto Neurologico C. Besta, 20133 Milano (Italy)

    2010-07-15

    Purpose: The main purpose of this work was to compare peripheral doses absorbed during stereotactic treatment of a brain lesion delivered using different devices. These data were used to estimate the risk of stochastic effects. Methods: Treatment plans were created for an anthropomorphic phantom and delivered using a LINAC with stereotactic cones and a multileaf collimator, a CyberKnife system (before and after a supplemental shielding was applied), a TomoTherapy system, and a Gamma Knife unit. For each treatment, 5 Gy were prescribed to the target. Measurements were performed with thermoluminescent dosimeters inserted roughly in the position of the thyroid, sternum, upper lung, lower lung, and gonads. Results: Mean doses ranged from of 4.1 (Gamma Knife) to 62.8 mGy (LINAC with cones) in the thyroid, from 2.3 (TomoTherapy) to 30 mGy (preshielding CyberKnife) in the sternum, from 1.7 (TomoTherapy) to 20 mGy (preshielding CyberKnife) in the upper part of the lungs, from 0.98 (Gamma Knife) to 15 mGy (preshielding CyberKnife) in the lower part of the lungs, and between 0.3 (Gamma Knife) and 10 mGy (preshielding CyberKnife) in the gonads. Conclusions: The peripheral dose absorbed in the sites of interest with a 5 Gy fraction is low. Although the risk of adverse side effects calculated for 20 Gy delivered in 5 Gy fractions is negligible, in the interest of optimum patient radioprotection, further studies are needed to determine the weight of each contributor to the peripheral dose.

  15. Evaluation of the peripheral dose in stereotactic radiotherapy and radiosurgery treatments

    International Nuclear Information System (INIS)

    Di Betta, Erika; Fariselli, Laura; Bergantin, Achille; Locatelli, Federica; Del Vecchio, Antonella; Broggi, Sara; Fumagalli, Maria Luisa

    2010-01-01

    Purpose: The main purpose of this work was to compare peripheral doses absorbed during stereotactic treatment of a brain lesion delivered using different devices. These data were used to estimate the risk of stochastic effects. Methods: Treatment plans were created for an anthropomorphic phantom and delivered using a LINAC with stereotactic cones and a multileaf collimator, a CyberKnife system (before and after a supplemental shielding was applied), a TomoTherapy system, and a Gamma Knife unit. For each treatment, 5 Gy were prescribed to the target. Measurements were performed with thermoluminescent dosimeters inserted roughly in the position of the thyroid, sternum, upper lung, lower lung, and gonads. Results: Mean doses ranged from of 4.1 (Gamma Knife) to 62.8 mGy (LINAC with cones) in the thyroid, from 2.3 (TomoTherapy) to 30 mGy (preshielding CyberKnife) in the sternum, from 1.7 (TomoTherapy) to 20 mGy (preshielding CyberKnife) in the upper part of the lungs, from 0.98 (Gamma Knife) to 15 mGy (preshielding CyberKnife) in the lower part of the lungs, and between 0.3 (Gamma Knife) and 10 mGy (preshielding CyberKnife) in the gonads. Conclusions: The peripheral dose absorbed in the sites of interest with a 5 Gy fraction is low. Although the risk of adverse side effects calculated for 20 Gy delivered in 5 Gy fractions is negligible, in the interest of optimum patient radioprotection, further studies are needed to determine the weight of each contributor to the peripheral dose.

  16. Radiotherapy

    International Nuclear Information System (INIS)

    Pistenma, D.A.

    1980-01-01

    The need for radiotherapy research is exemplified by the 100,000 cancer patients who will fail treatment locally and/or regionally annually for the next several years but who would benefit from better local treatment modalities. Theoretically, all of the areas of investigation discussed in this projection paper have the potential to significantly improve local-regional treatment of cancer by radiotherapy alone or in combination with other modalities. In many of the areas of investigation discussed in this paper encouraging results have been obtained in cellular and animal tumor studies and in limited studies in humans as well. In the not too distant future the number of patients who would benefit from better local control may increase by tens of thousands if developments in chemotherapy and/or immunotherapy provide a means to eradicate disseminated microscopic foci of cancer. Thus the efforts to improve local-regional control take on even greater significance

  17. Differences in pulmonary function before vs. 1 year after hypofractionated stereotactic radiotherapy for small peripheral lung tumors

    International Nuclear Information System (INIS)

    Ohashi, Toshio; Takeda, Atsuya; Shigematsu, Naoyuki; Kunieda, Etsuo; Ishizaka, Akitoshi; Fukada, Junichi; Deloar, Hossain M.; Kawaguchi, Osamu; Takeda, Toshiaki; Takemasa, Kazuhiko; Isobe, Kouichi; Kubo, Atsushi

    2005-01-01

    Purpose: To evaluate long-term pulmonary toxicity of stereotactic radiotherapy (SRT) by pulmonary function tests (PFTs) performed before and after SRT for small peripheral lung tumors. Methods and Materials: A total of 17 lesions in 15 patients with small peripheral lung tumors, who underwent SRT between February 2000 and April 2003, were included in this study. Twelve patients had primary lung cancer, and 3 patients had metastatic lung cancer. Primary lung cancer was T1-2N0M0 in all cases. Smoking history was assessed by the Brinkman index (number of cigarettes smoked per day multiplied by number of years of smoking). Prescribed radiation doses at the 80% isodose line were 40-60 Gy in 5-8 fractions. PFTs were performed immediately before SRT and 1 year after SRT. Test parameters included total lung capacity (TLC), vital capacity (VC), forced expiratory volume in 1 s (FEV1.0), and diffusing capacity of lung for carbon monoxide (DLCO). PFT changes were evaluated in relation to patient- and treatment-related factors, including age, the Brinkman index, internal target volume, the percentages of lung volume irradiated with >15, 20, 25, and 30 Gy (V15, V20, V25, and V30, respectively), and mean lung dose. Results: There were no significant changes in TLC, VC, or FEV1.0 before vs. after SRT. The mean percent change from baseline in DLCO was significantly increased by 128.2%. Univariate and multivariate analyses revealed a correlation between DLCO and the Brinkman index. Conclusions: One year after SRT as compared with before SRT, there were no declines in TLC, VC, and FEV1.0. DLCO improved in patients who had been heavy smokers before SRT, suggesting a correlation between DLCO and smoking cessation. SRT seems to be tolerable in view of long-term lung function

  18. Effect of central nervous system radiotherapy in children with acute lymphoblastic leukaemia on lymphocyte subpopulations and indicators of leucocyte migration inhibition in the peripheral blood

    International Nuclear Information System (INIS)

    Cesarz-Kruz, E.; Lukas, A; Sroczynska, M.; Lukas, W; Sonta-Jakimczyk, D.

    1981-01-01

    The reported investigations of changes in lymphocyte subpopulations and indicators of leycocyte migration inhibition in the peripheral blood were carried out in 17 children with acute lymphoblastic leukaemia subjected to prophylactic irradiation of the central nervous system. It was found that the depressive effect of radioprophylaxis affected mostly lymphocytes B. The usefulness of immunomodulation application in children with this leukaemia immediately after completion of radiotherapy is considered. (author)

  19. AA antiproton production target

    CERN Multimedia

    CERN PhotoLab

    1979-01-01

    The first version of the antiproton production target was a tungsten rod, 11 cm long and 3 mm in diameter. The rod was embedded in graphite, pressure-seated into an outer casing of stainless steel. At the entrance to the target assembly was a scintillator screen, imprinted with circles every 5 mm in radius, which allowed to precisely aim the 26 GeV high-intensity proton beam from the PS onto the centre of the target rod. The scintillator screen was a 1 mm thick plate of Cr-doped alumina. See also 7903034 and 7905091.

  20. AA antiproton production target

    CERN Multimedia

    CERN PhotoLab

    1979-01-01

    The first version of the antiproton production target was a tungsten rod, 11 cm long (actually a row of 11 rods, each 1 cm long) and 3 mm in diameter. The rod was embedded in graphite, pressure-seated into an outer casing made of stainless steel. The casing had fins for forced-air cooling. In this picture, the 26 GeV high-intensity beam from the PS enters from the right, where a scintillator screen, with circles every 5 mm in radius, permits precise aim at the target centre. See also 7903034 and 7905094.

  1. Search for antiproton decay at the Fermilab antiproton accumulator

    International Nuclear Information System (INIS)

    Geer, S.; Marriner, J.; Ray, R.; Streets, J.; Lindgren, M.; Muller, T.; Quackenbush, J.; Armstrong, T.

    1994-01-01

    A search for antiproton decay has been made at the Fermilab antiproton accumulator. Limits are placed on five antiproton decay modes. At the 95% C.L. we find that τ bar p /B(bar p→e - γ)>1848 yr, τ bar p /B(bar p→e 0 π 0 )>554 yr, τ bar p /B(bar p→e - η)>171 yr,τ bar p /B(bar p→e - K S 0 )>29 yr, and τ bar p /B(bar p→e - K L 0 )>9 yr

  2. Antiproton complex at the FAIR project

    International Nuclear Information System (INIS)

    Dolinskii, A.; Knie, K.; Dimopoulou, C.; Gostishchev, V.; Litvinov, S.; Nolden, F.; Steck, M.

    2011-01-01

    This report summarizes a set of calculations for the antiproton production in a complex composed of target area, collector, separator, beam line and collector ring for the antiproton source of the future FAIR facility (Facility for Antiproton and Ion Research) at GSI, Darmstadt, Germany. The emphasis is on the optimization of the accumulation rate of antiprotons in order to maximize the luminosity of experiments with cooled antiproton beams in the High Energy Storage Ring (HESR). Results of simulations for each component of the antiproton production complex are presented in order to identify the present limitations of the antiproton production rate.

  3. Analog measurement of delayed antiproton annihilation time spectra in a high intensity pulsed antiproton beam

    International Nuclear Information System (INIS)

    Niestroj, A.; Hayano, R.S.; Ishikawa, T.; Tamura, H.; Torii, H.A.; Morita, N.; Yamazaki, T.; Sugai, I.; Nakayoshi, K.; Horvath, D.; Eades, J.; Widmann, E.

    1996-01-01

    An analog detection system has been developed to measure delayed antiproton annihilation time spectra for laser resonance spectroscopy of metastable antiprotonic helium atoms using the high-intensity pulsed beam of antiprotons from LEAR at CERN. (orig.)

  4. A reservoir trap for antiprotons

    CERN Document Server

    Smorra, Christian; Franke, Kurt; Nagahama, Hiroki; Schneider, Georg; Higuchi, Takashi; Van Gorp, Simon; Blaum, Klaus; Matsuda, Yasuyuki; Quint, Wolfgang; Walz, Jochen; Yamazaki, Yasunori; Ulmer, Stefan

    2015-01-01

    We have developed techniques to extract arbitrary fractions of antiprotons from an accumulated reservoir, and to inject them into a Penning-trap system for high-precision measurements. In our trap-system antiproton storage times > 1.08 years are estimated. The device is fail-safe against power-cuts of up to 10 hours. This makes our planned comparisons of the fundamental properties of protons and antiprotons independent from accelerator cycles, and will enable us to perform experiments during long accelerator shutdown periods when background magnetic noise is low. The demonstrated scheme has the potential to be applied in many other precision Penning trap experiments dealing with exotic particles.

  5. Autoresonant Excitation of Antiproton Plasmas

    CERN Document Server

    Andresen, Gorm B; Baquero-Ruiz, Marcelo; Bertsche, William; Bowe, Paul D; Butler, Eoin; Carpenter, P T; Cesar, Claudio L; Chapman, Steven; Charlton, Michael; Fajans, Joel; Friesen, Tim; Fujiwara, Makoto C; Gill, David R; Hangst, Jeffrey S; Hardy, Walter N; Hayden, Michael E; Humphries, Andrew J; Hurt, J L; Hydomako, Richard; Jonsell, Svante; Madsen, Niels; Menary, Scott; Nolan, Paul; Olchanski, Konstantin; Olin, Art; Povilus, Alexander; Pusa, Petteri; Robicheaux, Francis; Sarid, Eli; Silveira, Daniel M; So, Chukman; Storey, James W; Thompson, Robert I; van der Werf, Dirk P; Wurtele, Jonathan S; Yamazaki, Yasunori

    2011-01-01

    We demonstrate controllable excitation of the center-of-mass longitudinal motion of a thermal antiproton plasma using a swept-frequency autoresonant drive. When the plasma is cold, dense, and highly collective in nature, we observe that the entire system behaves as a single-particle nonlinear oscillator, as predicted by a recent theory. In contrast, only a fraction of the antiprotons in a warm plasma can be similarly excited. Antihydrogen was produced and trapped by using this technique to drive antiprotons into a positron plasma, thereby initiating atomic recombination.

  6. Proton-antiproton collider physics

    CERN Document Server

    Altarelli, Guido

    1989-01-01

    This volume reviews the physics studied at the CERN proton-antiproton collider during its first phase of operation, from the first physics run in 1981 to the last one at the end of 1985. The volume consists of a series of review articles written by physicists who are actively involved with the collider research program. The first article describes the proton-antiproton collider facility itself, including the antiproton source and its principle of operation based on stochastic cooling. The subsequent six articles deal with the various physics subjects studied at the collider. Each article descr

  7. The Antiproton Accumulator (AA)

    CERN Multimedia

    1980-01-01

    Section 06 - 08*) of the AA where the dispersion (and hence the horizontal beam size) is large. One can distinguish (left to right): A vacuum-tank, two bending magnets (BST06 and BST07 in blue) with a quadrupole (QDN07, in red) in between, another vacuum-tank, a wide quadrupole (QFW08) and a further tank . The tanks are covered with heating tape for bake-out. The tank left of BST06 contained the stack core pickup for stochastic cooling (see 7906193, 7906190, 8005051), the two other tanks served mainly as vacuum chambers in the region where the beam was large. Peter Zettwoch works on BST06. *) see: H. Koziol, Antiproton Accumulator Parameter List, PS/AA/Note 84-2 (1984)

  8. The discovery of the antiproton

    International Nuclear Information System (INIS)

    Chamberlain, Owen

    1989-01-01

    A number of groups of particle physicists competed to provide track evidence of the existence of Dirac's postulated antiproton in the mid-1950s. The work of the several teams is described briefly. The author describes the work of his own group on the Bevatron in more detail, and how they finally observed the antiproton. The article finishes with an assessment of the importance of this discovery. (UK)

  9. Measurement of interaction between antiprotons

    Energy Technology Data Exchange (ETDEWEB)

    Adamczyk, L.; Adkins, J. K.; Agakishiev, G.; Aggarwal, M. M.; Ahammed, Z.; Alekseev, I.; Alford, J.; Aparin, A.; Arkhipkin, D.; Aschenauer, E. C.; Averichev, G. S.; Bairathi, V.; Banerjee, A.; Bellwied, R.; Bhasin, A.; Bhati, A. K.; Bhattarai, P.; Bielcik, J.; Bielcikova, J.; Bland, L. C.; Bordyuzhin, I. G.; Bouchet, J.; Brandenburg, J. D.; Brandin, A. V.; Bunzarov, I.; Butterworth, J.; Caines, H.; Calderón de la Barca Sánchez, M.; Campbell, J. M.; Cebra, D.; Cervantes, M. C.; Chakaberia, I.; Chaloupka, P.; Chang, Z.; Chattopadhyay, S.; Chen, J. H.; Chen, X.; Cheng, J.; Cherney, M.; Christie, W.; Contin, G.; Crawford, H. J.; Das, S.; De Silva, L. C.; Debbe, R. R.; Dedovich, T. G.; Deng, J.; Derevschikov, A. A.; di Ruzza, B.; Didenko, L.; Dilks, C.; Dong, X.; Drachenberg, J. L.; Draper, J. E.; Du, C. M.; Dunkelberger, L. E.; Dunlop, J. C.; Efimov, L. G.; Engelage, J.; Eppley, G.; Esha, R.; Evdokimov, O.; Eyser, O.; Fatemi, R.; Fazio, S.; Federic, P.; Fedorisin, J.; Feng, Z.; Filip, P.; Fisyak, Y.; Flores, C. E.; Fulek, L.; Gagliardi, C. A.; Garand, D.; Geurts, F.; Gibson, A.; Girard, M.; Greiner, L.; Grosnick, D.; Gunarathne, D. S.; Guo, Y.; Gupta, A.; Gupta, S.; Guryn, W.; Hamad, A.; Hamed, A.; Haque, R.; Harris, J. W.; He, L.; Heppelmann, S.; Heppelmann, S.; Hirsch, A.; Hoffmann, G. W.; Hofman, D. J.; Horvat, S.; Huang, B.; Huang, H. Z.; Huang, X.; Huck, P.; Humanic, T. J.; Igo, G.; Jacobs, W. W.; Jang, H.; Jiang, K.; Judd, E. G.; Kabana, S.; Kalinkin, D.; Kang, K.; Kauder, K.; Ke, H. W.; Keane, D.; Kechechyan, A.; Khan, Z. H.; Kikoła, D. P.; Kisel, I.; Kisiel, A.; Klein, S.; Kochenda, L.; Koetke, D. D.; Kollegger, T.; Kosarzewski, L. K.; Kraishan, A. F.; Kravtsov, P.; Krueger, K.; Kulakov, I.; Kumar, L.; Kycia, R. A.; Lamont, M. A. C.; Landgraf, J. M.; Landry, K. D.; Lauret, J.; Lebedev, A.; Lednicky, R.; Lee, J. H.; Li, X.; Li, Z. M.; Li, Y.; Li, W.; Li, X.; Li, C.; Lisa, M. A.; Liu, F.; Ljubicic, T.; Llope, W. J.; Lomnitz, M.; Longacre, R. S.; Luo, X.; Ma, G. L.; Ma, R.; Ma, Y. G.; Ma, L.; Magdy, N.; Majka, R.; Manion, A.; Margetis, S.; Markert, C.; Masui, H.; Matis, H. S.; McDonald, D.; Meehan, K.; Minaev, N. G.; Mioduszewski, S.; Mishra, D.; Mohanty, B.; Mondal, M. M.; Morozov, D. A.; Mustafa, M. K.; Nandi, B. K.; Nasim, Md.; Nayak, T. K.; Nigmatkulov, G.; Nogach, L. V.; Noh, S. Y.; Novak, J.; Nurushev, S. B.; Odyniec, G.; Ogawa, A.; Oh, K.; Okorokov, V.; Olvitt, D.; Page, B. S.; Pak, R.; Pan, Y. X.; Pandit, Y.; Panebratsev, Y.; Pawlik, B.; Pei, H.; Perkins, C.; Peterson, A.; Pile, P.; Planinic, M.; Pluta, J.; Poljak, N.; Poniatowska, K.; Porter, J.; Posik, M.; Poskanzer, A. M.; Putschke, J.; Qiu, H.; Quintero, A.; Ramachandran, S.; Raniwala, R.; Raniwala, S.; Ray, R. L.; Ritter, H. G.; Roberts, J. B.; Rogachevskiy, O. V.; Romero, J. L.; Roy, A.; Ruan, L.; Rusnak, J.; Rusnakova, O.; Sahoo, N. R.; Sahu, P. K.; Sakrejda, I.; Salur, S.; Sandweiss, J.; Sarkar, A.; Schambach, J.; Scharenberg, R. P.; Schmah, A. M.; Schmidke, W. B.; Schmitz, N.; Seger, J.; Seyboth, P.; Shah, N.; Shahaliev, E.; Shanmuganathan, P. V.; Shao, M.; Sharma, M. K.; Sharma, B.; Shen, W. Q.; Shi, S. S.; Shou, Q. Y.; Sichtermann, E. P.; Sikora, R.; Simko, M.; Skoby, M. J.; Smirnov, N.; Smirnov, D.; Song, L.; Sorensen, P.; Spinka, H. M.; Srivastava, B.; Stanislaus, T. D. S.; Stepanov, M.; Stock, R.; Strikhanov, M.; Stringfellow, B.; Sumbera, M.; Summa, B.; Sun, Z.; Sun, X. M.; Sun, Y.; Sun, X.; Surrow, B.; Svirida, N.; Szelezniak, M. A.; Tang, Z.; Tang, A. H.; Tarnowsky, T.; Tawfik, A.; Thomas, J. H.; Timmins, A. R.; Tlusty, D.; Tokarev, M.; Trentalange, S.; Tribble, R. E.; Tribedy, P.; Tripathy, S. K.; Trzeciak, B. A.; Tsai, O. D.; Ullrich, T.; Underwood, D. G.; Upsal, I.; Van Buren, G.; van Nieuwenhuizen, G.; Vandenbroucke, M.; Varma, R.; Vasiliev, A. N.; Vertesi, R.; Videbæk, F.; Viyogi, Y. P.; Vokal, S.; Voloshin, S. A.; Vossen, A.; Wang, G.; Wang, H.; Wang, J. S.; Wang, Y.; Wang, Y.; Wang, F.; Webb, J. C.; Webb, G.; Wen, L.; Westfall, G. D.; Wieman, H.; Wissink, S. W.; Witt, R.; Wu, Y. F.; Xiao, Z. G.; Xie, W.; Xin, K.; Xu, Y. F.; Xu, Q. H.; Xu, H.; Xu, N.; Xu, Z.; Yang, Y.; Yang, C.; Yang, S.; Yang, Y.; Yang, Q.; Ye, Z.; Yepes, P.; Yi, L.; Yip, K.; Yoo, I. -K.; Yu, N.; Zbroszczyk, H.; Zha, W.; Zhang, J. B.; Zhang, Z.; Zhang, J.; Zhang, S.; Zhang, X. P.; Zhang, J.; Zhang, Y.; Zhao, J.; Zhong, C.; Zhou, L.; Zhu, X.; Zoulkarneeva, Y.; Zyzak, M.

    2015-11-04

    © 2015 Macmillan Publishers Limited. All rights reserved. One of the primary goals of nuclear physics is to understand the force between nucleons, which is a necessary step for understanding the structure of nuclei and how nuclei interact with each other. Rutherford discovered the atomic nucleus in 1911, and the large body of knowledge about the nuclear force that has since been acquired was derived from studies made on nucleons or nuclei. Although antinuclei up to antihelium-4 have been discovered and their masses measured, little is known directly about the nuclear force between antinucleons. Here, we study antiproton pair correlations among data collected by the STAR experiment at the Relativistic Heavy Ion Collider (RHIC), where gold ions are collided with a centre-of-mass energy of 200 gigaelectronvolts per nucleon pair. Antiprotons are abundantly produced in such collisions, thus making it feasible to study details of the antiproton-antiproton interaction. By applying a technique similar to Hanbury Brown and Twiss intensity interferometry, we show that the force between two antiprotons is attractive. In addition, we report two key parameters that characterize the corresponding strong interaction: the scattering length and the effective range of the interaction. Our measured parameters are consistent within errors with the corresponding values for proton-proton interactions. Our results provide direct information on the interaction between two antiprotons, one of the simplest systems of antinucleons, and so are fundamental to understanding the structure of more-complex antinuclei and the ir properties.

  10. Measurement of interaction between antiprotons

    Science.gov (United States)

    The Star Collaboration; Adamczyk, L.; Adkins, J. K.; Agakishiev, G.; Aggarwal, M. M.; Ahammed, Z.; Alekseev, I.; Alford, J.; Aparin, A.; Arkhipkin, D.; Aschenauer, E. C.; Averichev, G. S.; Bairathi, V.; Banerjee, A.; Bellwied, R.; Bhasin, A.; Bhati, A. K.; Bhattarai, P.; Bielcik, J.; Bielcikova, J.; Bland, L. C.; Bordyuzhin, I. G.; Bouchet, J.; Brandenburg, J. D.; Brandin, A. V.; Bunzarov, I.; Butterworth, J.; Caines, H.; Calderón de La Barca Sánchez, M.; Campbell, J. M.; Cebra, D.; Cervantes, M. C.; Chakaberia, I.; Chaloupka, P.; Chang, Z.; Chattopadhyay, S.; Chen, J. H.; Chen, X.; Cheng, J.; Cherney, M.; Christie, W.; Contin, G.; Crawford, H. J.; Das, S.; de Silva, L. C.; Debbe, R. R.; Dedovich, T. G.; Deng, J.; Derevschikov, A. A.; di Ruzza, B.; Didenko, L.; Dilks, C.; Dong, X.; Drachenberg, J. L.; Draper, J. E.; Du, C. M.; Dunkelberger, L. E.; Dunlop, J. C.; Efimov, L. G.; Engelage, J.; Eppley, G.; Esha, R.; Evdokimov, O.; Eyser, O.; Fatemi, R.; Fazio, S.; Federic, P.; Fedorisin, J.; Feng, Z.; Filip, P.; Fisyak, Y.; Flores, C. E.; Fulek, L.; Gagliardi, C. A.; Garand, D.; Geurts, F.; Gibson, A.; Girard, M.; Greiner, L.; Grosnick, D.; Gunarathne, D. S.; Guo, Y.; Gupta, A.; Gupta, S.; Guryn, W.; Hamad, A.; Hamed, A.; Haque, R.; Harris, J. W.; He, L.; Heppelmann, S.; Heppelmann, S.; Hirsch, A.; Hoffmann, G. W.; Hofman, D. J.; Horvat, S.; Huang, B.; Huang, H. Z.; Huang, X.; Huck, P.; Humanic, T. J.; Igo, G.; Jacobs, W. W.; Jang, H.; Jiang, K.; Judd, E. G.; Kabana, S.; Kalinkin, D.; Kang, K.; Kauder, K.; Ke, H. W.; Keane, D.; Kechechyan, A.; Khan, Z. H.; Kikoła, D. P.; Kisel, I.; Kisiel, A.; Klein, S.; Kochenda, L.; Koetke, D. D.; Kollegger, T.; Kosarzewski, L. K.; Kraishan, A. F.; Kravtsov, P.; Krueger, K.; Kulakov, I.; Kumar, L.; Kycia, R. A.; Lamont, M. A. C.; Landgraf, J. M.; Landry, K. D.; Lauret, J.; Lebedev, A.; Lednicky, R.; Lee, J. H.; Li, X.; Li, Z. M.; Li, Y.; Li, W.; Li, X.; Li, C.; Lisa, M. A.; Liu, F.; Ljubicic, T.; Llope, W. J.; Lomnitz, M.; Longacre, R. S.; Luo, X.; Ma, G. L.; Ma, R.; Ma, Y. G.; Ma, L.; Magdy, N.; Majka, R.; Manion, A.; Margetis, S.; Markert, C.; Masui, H.; Matis, H. S.; McDonald, D.; Meehan, K.; Minaev, N. G.; Mioduszewski, S.; Mishra, D.; Mohanty, B.; Mondal, M. M.; Morozov, D. A.; Mustafa, M. K.; Nandi, B. K.; Nasim, Md.; Nayak, T. K.; Nigmatkulov, G.; Nogach, L. V.; Noh, S. Y.; Novak, J.; Nurushev, S. B.; Odyniec, G.; Ogawa, A.; Oh, K.; Okorokov, V.; Olvitt, D.; Page, B. S.; Pak, R.; Pan, Y. X.; Pandit, Y.; Panebratsev, Y.; Pawlik, B.; Pei, H.; Perkins, C.; Peterson, A.; Pile, P.; Planinic, M.; Pluta, J.; Poljak, N.; Poniatowska, K.; Porter, J.; Posik, M.; Poskanzer, A. M.; Putschke, J.; Qiu, H.; Quintero, A.; Ramachandran, S.; Raniwala, R.; Raniwala, S.; Ray, R. L.; Ritter, H. G.; Roberts, J. B.; Rogachevskiy, O. V.; Romero, J. L.; Roy, A.; Ruan, L.; Rusnak, J.; Rusnakova, O.; Sahoo, N. R.; Sahu, P. K.; Sakrejda, I.; Salur, S.; Sandweiss, J.; Sarkar, A.; Schambach, J.; Scharenberg, R. P.; Schmah, A. M.; Schmidke, W. B.; Schmitz, N.; Seger, J.; Seyboth, P.; Shah, N.; Shahaliev, E.; Shanmuganathan, P. V.; Shao, M.; Sharma, M. K.; Sharma, B.; Shen, W. Q.; Shi, S. S.; Shou, Q. Y.; Sichtermann, E. P.; Sikora, R.; Simko, M.; Skoby, M. J.; Smirnov, N.; Smirnov, D.; Song, L.; Sorensen, P.; Spinka, H. M.; Srivastava, B.; Stanislaus, T. D. S.; Stepanov, M.; Stock, R.; Strikhanov, M.; Stringfellow, B.; Sumbera, M.; Summa, B.; Sun, Z.; Sun, X. M.; Sun, Y.; Sun, X.; Surrow, B.; Svirida, N.; Szelezniak, M. A.; Tang, Z.; Tang, A. H.; Tarnowsky, T.; Tawfik, A.; Thomas, J. H.; Timmins, A. R.; Tlusty, D.; Tokarev, M.; Trentalange, S.; Tribble, R. E.; Tribedy, P.; Tripathy, S. K.; Trzeciak, B. A.; Tsai, O. D.; Ullrich, T.; Underwood, D. G.; Upsal, I.; van Buren, G.; van Nieuwenhuizen, G.; Vandenbroucke, M.; Varma, R.; Vasiliev, A. N.; Vertesi, R.; Videbæk, F.; Viyogi, Y. P.; Vokal, S.; Voloshin, S. A.; Vossen, A.; Wang, G.; Wang, H.; Wang, J. S.; Wang, Y.; Wang, Y.; Wang, F.; Webb, J. C.; Webb, G.; Wen, L.; Westfall, G. D.; Wieman, H.; Wissink, S. W.; Witt, R.; Wu, Y. F.; Xiao, Z. G.; Xie, W.; Xin, K.; Xu, Y. F.; Xu, Q. H.; Xu, H.; Xu, N.; Xu, Z.; Yang, Y.; Yang, C.; Yang, S.; Yang, Y.; Yang, Q.; Ye, Z.; Yepes, P.; Yi, L.; Yip, K.; Yoo, I.-K.; Yu, N.; Zbroszczyk, H.; Zha, W.; Zhang, J. B.; Zhang, Z.; Zhang, J.; Zhang, S.; Zhang, X. P.; Zhang, J.; Zhang, Y.; Zhao, J.; Zhong, C.; Zhou, L.; Zhu, X.; Zoulkarneeva, Y.; Zyzak, M.

    2015-11-01

    One of the primary goals of nuclear physics is to understand the force between nucleons, which is a necessary step for understanding the structure of nuclei and how nuclei interact with each other. Rutherford discovered the atomic nucleus in 1911, and the large body of knowledge about the nuclear force that has since been acquired was derived from studies made on nucleons or nuclei. Although antinuclei up to antihelium-4 have been discovered and their masses measured, little is known directly about the nuclear force between antinucleons. Here, we study antiproton pair correlations among data collected by the STAR experiment at the Relativistic Heavy Ion Collider (RHIC), where gold ions are collided with a centre-of-mass energy of 200 gigaelectronvolts per nucleon pair. Antiprotons are abundantly produced in such collisions, thus making it feasible to study details of the antiproton-antiproton interaction. By applying a technique similar to Hanbury Brown and Twiss intensity interferometry, we show that the force between two antiprotons is attractive. In addition, we report two key parameters that characterize the corresponding strong interaction: the scattering length and the effective range of the interaction. Our measured parameters are consistent within errors with the corresponding values for proton-proton interactions. Our results provide direct information on the interaction between two antiprotons, one of the simplest systems of antinucleons, and so are fundamental to understanding the structure of more-complex antinuclei and their properties.

  11. Antiproton Cancer Therapy

    DEFF Research Database (Denmark)

    Bassler, Niels

    An essential part in cancer radiotherapy, is to direct a sufficiently high dose towards the tumour, without damaging the surrounding tissue. Different techniques such as intensity modulated radiation therapy and proton therapy have been developed, in order to reduce the dose to the normal tissue...

  12. Comparison of electromagnetic and hadronic models generated using Geant 4 with antiproton dose measured in CERN.

    Science.gov (United States)

    Tavakoli, Mohammad Bagher; Reiazi, Reza; Mohammadi, Mohammad Mehdi; Jabbari, Keyvan

    2015-01-01

    After proposing the idea of antiproton cancer treatment in 1984 many experiments were launched to investigate different aspects of physical and radiobiological properties of antiproton, which came from its annihilation reactions. One of these experiments has been done at the European Organization for Nuclear Research known as CERN using the antiproton decelerator. The ultimate goal of this experiment was to assess the dosimetric and radiobiological properties of beams of antiprotons in order to estimate the suitability of antiprotons for radiotherapy. One difficulty on this way was the unavailability of antiproton beam in CERN for a long time, so the verification of Monte Carlo codes to simulate antiproton depth dose could be useful. Among available simulation codes, Geant4 provides acceptable flexibility and extensibility, which progressively lead to the development of novel Geant4 applications in research domains, especially modeling the biological effects of ionizing radiation at the sub-cellular scale. In this study, the depth dose corresponding to CERN antiproton beam energy by Geant4 recruiting all the standard physics lists currently available and benchmarked for other use cases were calculated. Overall, none of the standard physics lists was able to draw the antiproton percentage depth dose. Although, with some models our results were promising, the Bragg peak level remained as the point of concern for our study. It is concluded that the Bertini model with high precision neutron tracking (QGSP_BERT_HP) is the best to match the experimental data though it is also the slowest model to simulate events among the physics lists.

  13. The Antiproton Accumulator (AA)

    CERN Multimedia

    1980-01-01

    A section of the AA where the dispersion (and hence the horizontal beam size) is large. One can distinguish (left to right): A large vacuum-tank, a quadrupole (QDN09*), a bending magnet (BST08), another vacuum-tank, a wide quadrupole (QFW08) and (in the background) a further bending magnet (BST08). The tanks are covered with heating tape for bake-out. The tank left of QDN09 contained the kickers for stochastic pre-cooling (see 790621, 8002234, 8002637X), the other one served mainly as vacuum chamber in the region where the beam was large. Peter Zettwoch works on QFW08. * see: H. Koziol, Antiproton Accumulator Parameter List, PS/AA/Note 84-2 (1984) See under 7911303, 7911597X, 8004261 and 8202324. For photos of the AA in different phases of completion (between 1979 and 1982) see: 7911303, 7911597X, 8004261, 8004608X, 8005563X, 8005565X, 8006716X, 8006722X, 8010939X, 8010941X, 8202324, 8202658X, 8203628X .

  14. Antiprotonic helium atomcules

    Directory of Open Access Journals (Sweden)

    Sauge Sébastien

    2012-10-01

    Full Text Available About 3% of antiprotons ( stopped in helium are long-lived with microsecond lifetimes, against picoseconds in all other materials. This unusual longevity has been ascribed to the trapping of on metastable bound states in He+ helium atom-molecules thus named atomcules. Apart from their unique dual structure investigated by laser spectroscopy – a near-circular quasi-classical Rydberg atom with l ~ n – 1 ~ 37 or a special diatomic molecule with a negatively charged nucleus in high rotational state with J = l – the chemical physics aspects of their interaction with other atoms or molecules constitute an interesting topic for molecular physics. While atomcules may resist to million collisions in helium, molecular contaminants such as H2 are likely to destroy them in a single one, down to very low temperatures. In the Born-Oppenheimer framework, we interpret the molecular interaction obtained by ab initio quantum chemical calculations in terms of classical reactive channels, with activation barriers accounting for the experiments carried out in He and H2. From classical trajectory Monte Carlo simulations, we show that the thermalization stage strongly quenches initial populations, thus reduced to a recovered 3 % trapping fraction. This work illustrates the pertinence of chemical physics concepts to the study of exotic processes involving antimatter. New insights into the physico-chemistry of cold interstellar radicals are anticipated.

  15. In the steps of the antiproton

    CERN Multimedia

    Amsler, Claude

    2015-01-01

    Sixty years after the discovery of the antiproton at Berkeley, a look at some of the ways that studies with antiprotons at CERN have cast light on basic physics and, in particular, on fundamental symmetries.

  16. Spectroscopy of antiproton helium atoms

    International Nuclear Information System (INIS)

    Hayano, Ryugo

    2005-01-01

    Antiproton helium atom is three-body system consisting of an antiproton, electrons and a helium nucleus (denoted by the chemical symbol, p-bar H + ). The authors produced abundant atoms of p-bar 4 He + , and p-bar 3 He + in a cooled He gas target chamber stopping the p-bar beam decelerated to approximately 100 keV in the Antiproton Decelerator at CERN. A precision laser spectroscopy on the atomic transitions in the p-bar 4 He + , and in p-bar 3 He + was performed. Principle of laser spectroscopy and various modifications of the system to eliminate factors affecting the accuracy of the experiment were described. Deduced mass ratio of antiproton and proton, (|m p -bar - m p |)/m p reached to the accuracy of 10 ppb (10 -8 ) as of 2002, as adopted in the recent article of the Particle Data Group by P.J. Mohr and B.N. Taylor. This value is the highest precise data for the CPT invariance in baryon. In future, antihydrogen atoms will be produced in the same facility, and will provide far accurate value of antiproton mass thus enabling a better confirmation of CPT theorem in baryon. (T. Tamura)

  17. PHYSICS WITH ULTRA-LOW ENERGY ANTIPROTONS

    Energy Technology Data Exchange (ETDEWEB)

    M. HOLZSCHEITER

    2001-02-01

    In this report the author describes the current status of the antiproton deceleration (AD) facility at CERN, and highlights the physics program with ultra-low energy antiproton at this installation. He also comments on future possibilities provided higher intensity antiproton beams become available at Fermilab, and review possibilities for initial experiments using direct degrading of high energy antiprotons in material has been developed and proven at CERN.

  18. Compression of Antiproton Clouds for Antihydrogen Trapping

    CERN Document Server

    Andresen, G B; Bowe, P D; Bray, C C; Butler, E; Cesar, C L; Chapman, S; Charlton, M; Fajans, J; Fujiwara, M C; Funakoshi, R; Gill, D R; Hangst, J S; Hardy, W N; Hayano, R S; Hayden, M E; Hydomako, R; Jenkins, M J; Jørgensen, L V; Kurchaninov, L; Lambo, R; Madsen, N; Nolan, P; Olchanski, K; Olin, A; Povilus, A; Pusa, P; Robicheaux, F; Sarid, E; Seif El Nasr, S; Silveira, D M; Storey, J W; Thompson, R I; Van der Werf, D P; Wurtele, J S; Yamazaki, Y

    2008-01-01

    Control of the radial profile of trapped antiproton clouds is critical to trapping antihydrogen. We report the first detailed measurements of the radial manipulation of antiproton clouds, including areal density compressions by factors as large as ten, by manipulating spatially overlapped electron plasmas. We show detailed measurements of the near-axis antiproton radial profile and its relation to that of the electron plasma.

  19. Unstable chromosome aberrations on peripheral blood lymphocytes from patients with cervical uterine cancer following radiotherapy; Aberracoes cromossomicas instaveis em linfocitos de pacientes com cancer de colo de utero

    Energy Technology Data Exchange (ETDEWEB)

    Magnata, Simey de Souza Leao Pereira

    2002-09-01

    Absorbed dose determination is an important step for risk assessment related to an exposure to ionizing radiation. However, physical dosimetry cannot be always performed, principally in the case of retrospective estimates. In this context, the use of bioindicators (biological effects) has been proposed, which defines the so-called biological dosimetry. In particular, scoring of unstable chromosomes aberrations (dicentrics, centric rings and fragments) of peripheral blood lymphocytes, while is the most reliable biological method for estimating individual exposure to ionizing radiation. In this work, blood samples from 5 patients, with cervical uterine cancer, were evaluated after partial-body radiotherapy with a source of {sup 69} Co. For this, conventional cytogenetic method was employed, based on Giemsa coloration and fluorescence in situ hybridization, in order to correlate the frequency of unstable chromosome aberrations of blood lymphocytes with absorbed dose, as a result of the radiotherapy. A good agreement was observed between the frequency of chromosome aberrations scored and the values of dose previously calculated by physical dosimetry during patient's radiotherapy. The results presented in this work point out the importance of concerning analyses of unstable chromosome aberrations as biological dosimeter in the investigation of partial-body exposure to ionizing radiation. (author)

  20. Unstable chromosome aberrations on peripheral blood lymphocytes from patients with cervical uterine cancer following radiotherapy; Aberracoes cromossomicas instaveis em linfocitos de pacientes com cancer de colo de utero

    Energy Technology Data Exchange (ETDEWEB)

    Magnata, Simey de Souza Leao Pereira

    2002-09-01

    Absorbed dose determination is an important step for risk assessment related to an exposure to ionizing radiation. However, physical dosimetry cannot be always performed, principally in the case of retrospective estimates. In this context, the use of bioindicators (biological effects) has been proposed, which defines the so-called biological dosimetry. In particular, scoring of unstable chromosomes aberrations (dicentrics, centric rings and fragments) of peripheral blood lymphocytes, while is the most reliable biological method for estimating individual exposure to ionizing radiation. In this work, blood samples from 5 patients, with cervical uterine cancer, were evaluated after partial-body radiotherapy with a source of {sup 69} Co. For this, conventional cytogenetic method was employed, based on Giemsa coloration and fluorescence in situ hybridization, in order to correlate the frequency of unstable chromosome aberrations of blood lymphocytes with absorbed dose, as a result of the radiotherapy. A good agreement was observed between the frequency of chromosome aberrations scored and the values of dose previously calculated by physical dosimetry during patient's radiotherapy. The results presented in this work point out the importance of concerning analyses of unstable chromosome aberrations as biological dosimeter in the investigation of partial-body exposure to ionizing radiation. (author)

  1. Antiproton collisions with molecular hydrogen

    DEFF Research Database (Denmark)

    Lühr, Armin Christian; Saenz, Alejandro

    2008-01-01

    Theoretical antiproton and proton cross sections for ionization and excitation of hydrogen molecules as well as energy spectra of the ionized electrons were calculated in the impact-energy range from 8  to  4000  keV. The cross sections were computed with the close-coupling formulation of the sem......Theoretical antiproton and proton cross sections for ionization and excitation of hydrogen molecules as well as energy spectra of the ionized electrons were calculated in the impact-energy range from 8  to  4000  keV. The cross sections were computed with the close-coupling formulation...

  2. Measurement of interaction between antiprotons

    Czech Academy of Sciences Publication Activity Database

    Adamczyk, L.; Bielčík, J.; Bielčíková, Jana; Federič, Pavol; Chaloupka, P.; Rusňák, Jan; Rusňáková, O.; Šimko, Miroslav; Šumbera, Michal; Tlustý, David; Trzeciak, B. A.; Vértési, Robert

    2015-01-01

    Roč. 527, č. 7578 (2015), s. 345-348 ISSN 0028-0836 R&D Projects: GA ČR GA13-20841S Institutional support: RVO:61389005 Keywords : STAR collaboration * antiprotons * protons Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders Impact factor: 38.138, year: 2015

  3. Physics at CERN's Antiproton Decelerator

    CERN Document Server

    Hori, M

    2013-01-01

    The Antiproton Decelerator of CERN began operation in 1999 to serve experiments for studies of CPT invariance by precision laser and microwave spectroscopy of antihydrogen ($\\bar{\\rm H}$) and antiprotonic helium ($\\bar{p}{\\rm He}^+$). The first 12 years of operation saw cold $\\bar{\\rm H}$ synthesized by overlapping clouds of positrons ($e^+$) and antiprotons ($\\bar{p}$) confined in magnetic Penning traps. Cold $\\bar{\\rm H}$ was also produced in collisions between Rydberg positronium atoms and $\\bar{p}$. Ground-state $\\bar{\\rm H}$ was later trapped for up to $\\sim 1000$ s in a magnetic bottle trap, and microwave transitions excited between its hyperfine levels. In the $\\bar{p}{\\rm He}^+$ atom, UV transitions were measured to a precision of (2.3-5) $\\times$ $10^{-9}$ by sub-Doppler two-photon laser spectroscopy. From this the antiproton-to-electron mass ratio was determined as $M_{\\bar{p}}/m_e=$1836.1526736(23), which agrees with the p value. Microwave spectroscopy of $\\bar{p}{\\rm He}^+$ yielded a measurement o...

  4. Peripheral myeloid-derived suppressor and T regulatory PD-1 positive cells predict response to neoadjuvant short-course radiotherapy in rectal cancer patients

    Science.gov (United States)

    Napolitano, Maria; D'Alterio, Crescenzo; Cardone, Eleonora; Trotta, Anna Maria; Pecori, Biagio; Rega, Daniela; Pace, Ugo; Scala, Dario; Scognamiglio, Giosuè; Tatangelo, Fabiana; Cacciapuoti, Carmela; Pacelli, Roberto; Delrio, Paolo; Scala, Stefania

    2015-01-01

    Short-course preoperative radiotherapy (SC-RT) followed by total mesorectal excision (TME) is one therapeutic option for locally advanced rectal cancer (LARC) patients. Since radio-induced DNA damage may affect tumor immunogenicity, Myeloid-derived suppressor cells (MDSCs) and T regulatory cells (Tregs) were evaluated in 13 patients undergoing SC-RT and TME for LARC. Peripheral Granulocytic-MDSCs (G-MDSC) [LIN−/HLA-DR−/CD11b+/CD14−/CD15+/CD33+], Monocytic (M-MDSC) [CD14+/HLA-DR−/lowCD11b+/CD33+] and Tregs [CD4+/CD25hi+/FOXP3+- CTLA-4/PD1] basal value was significantly higher in LARC patients compared to healthy donors (HD). Peripheral MDSC and Tregs were evaluated at time 0 (T0), after 2 and 5 weeks (T2-T5) from radiotherapy; before surgery (T8) and 6–12 months after surgery (T9, T10). G-MDSC decreased at T5 and further at T8 while M-MDSC cells decreased at T5; Tregs reached the lowest value at T5. LARC poor responder patients displayed a major decrease in M-MDSC after SC-RT and an increase of Treg-PD-1. In this pilot study MDSCs and Tregs decrease during the SC-RT treatment could represent a biomarker of response in LARC patients. Further studies are needed to confirm that the deepest M-MDSC reduction and increase in Treg-PD1 cells within 5–8 weeks from the beginning of treatment could discriminate LARC patients poor responding to SC-RT. PMID:25823653

  5. Experimental setup and first measurement of DNA damage induced along and around an antiproton beam

    DEFF Research Database (Denmark)

    Kavanagh, J. N.; Currell, F. J.; Timson, D. J.

    2010-01-01

    a further enhancement due to their annihilation at the end of the path. The work presented here aimed to establish and validate an experimental procedure for the quantification of plasmid and genomic DNA damage resulting from antiproton exposure. Immunocytochemistry was used to assess DNA damage in directly......Radiotherapy employs ionizing radiation to induce lethal DNA lesions in cancer cells while minimizing damage to healthy tissues. Due to their pattern of energy deposition, better therapeutic outcomes can, in theory, be achieved with ions compared to photons. Antiprotons have been proposed to offer...... and indirectly exposed human fibroblasts irradiated in both plateau and Bragg peak regions of a 126 MeV antiproton beam at CERN. Cells were stained post irradiation with an anti-γ-H2AX antibody. Quantification of the γ-H2AX foci-dose relationship is consistent with a linear increase in the Bragg peak region...

  6. Anitproton-matter interactions in antiproton applications

    Science.gov (United States)

    Morgan, David L., Jr.

    1990-01-01

    By virtue of the highly energetic particles released when they annihilate in matter, antiprotons have a variety of potentially important applications. Among others, these include remote 3-D density and composition imaging of the human body and also of thick, dense materials, cancer therapy, and spacecraft propulsion. Except for spacecraft propulsion, the required numbers of low energy antiprotons can be produced, stored, and transported through reliance on current or near term technology. Paramount to these applications and to fundamental research involving antiprotons is knowledge of how antiprotons interact with matter. The basic annihilation process is fairly well understood, but the antiproton annihilation and energy loss rates in matter depend in complex ways on a number of atomic processes. The rates, and the corresponding cross sections, were measured or are accurately predictable only for limited combinations of antiproton kinetic energy and material species.

  7. The future of the antiproton accumulator

    International Nuclear Information System (INIS)

    Autin, B.

    1983-01-01

    When the Antiproton Accumulator was designed in 1977, it was considered as an element of the high energy proton-antiproton collision experiments in the CERN Super Proton Synchrotron. Since that time, antiproton physics has become more and more popular: a second experimental area was built in the SPS, the Intersecting Storage Rings started a special antiproton programme and a considerable interest has bloomed in the energy range of nuclear physics with the LEAR machine. Moreover, any projection on hadron physics in the coming years shows an insatiable appetite of experimentalists for more antiprotons. Therefore, basic studies have been pursued since the beginning of last year to transform the accumulator into an abundant source of antiprotons

  8. Antiproton source beam position system

    International Nuclear Information System (INIS)

    Bagwell, T.; Holmes, S.; McCarthy, J.; Webber, R.

    1984-05-01

    The TeV I Beam Position Monitor (BPM) system is designed to provide a useful diagnostic tool during the commissioning and operational phases of the antiproton source. Simply stated the design goal is to provide single turn position information for intensities of > 1x10 9 particles, and multi-turn (clocked orbit) information for beam intensities of > 1x10 7 particles, both with sub-millimeter resolution. It is anticipated that the system will be used during commissioning for establishing the first turn through the Debuncher and Accumulator, for aligning injection orbits, for providing information necessary to correct closed orbits, and for measuring various machine parameters (e.g. tunes, dispersion, aperture, chromaticity). During normal antiproton operation the system will be used to monitor the beam position throughout the accumulation process

  9. Radiation studies in the antiproton source

    International Nuclear Information System (INIS)

    Church, M.

    1990-01-01

    Experiment E760 has a lead glass (Pb-G) calorimeter situated in the antiproton source tunnel in the accumulator ring at location A50. This location is exposed to radiation from several sources during antiproton stacking operations. A series of radiation studies has been performed over the last two years to determine the sources of this radiation and as a result, some shielding has been installed in the antiproton source in order to protect the lead glass from radiation damage

  10. Design study of an Antiproton Collector for the Antiproton Accumulator (ACOL)

    International Nuclear Information System (INIS)

    Wilson, E.J.N.

    1983-01-01

    The Report gives a full description of an Antiproton Collector Ring which, placed around the existing Antiproton Accumulator at CERN, would enhance the antiproton flux available to both the SPS and LEAR by a factor of ten. The new ring and the focusing devices which precede it are designed to accept a much larger fraction of the antiproton production cone from the target. Each pulse of particles will be pre-cooled before being fed to the Antiproton Accumulator, where improved stochastic cooling systems will build up the stack. A full list of parameters is included. (orig.)

  11. Antiproton annihilation physics annihilation physics in the Monte Carlo particle transport code particle transport code SHIELD-HIT12A

    DEFF Research Database (Denmark)

    Taasti, Vicki Trier; Knudsen, Helge; Holzscheiter, Michael

    2015-01-01

    The Monte Carlo particle transport code SHIELD-HIT12A is designed to simulate therapeutic beams for cancer radiotherapy with fast ions. SHIELD-HIT12A allows creation of antiproton beam kernels for the treatment planning system TRiP98, but first it must be benchmarked against experimental data. An...

  12. The Fermilab proton-antiproton collider upgrades

    International Nuclear Information System (INIS)

    Marriner, J.P.

    1996-10-01

    The plans for increases in the Tevatron proton-antiproton collider luminosity in the near future (Run II) and the more distant future (TeV33) are described. While there are many important issues, the fundamental requirement is to produce more antiprotons and to use them more efficiently

  13. PANDA : Strong Interaction Studies with Antiprotons

    NARCIS (Netherlands)

    Peters, Klaus; Schmitt, Lars; Stockmanns, Tobias; Messchendorp, Johan

    2017-01-01

    The Antiproton Anihilation in Darmstadt (PANDA) collaboration at the Facility for Antiproton and Ion Research (FAIR) is a cooperation of more than 400 scientists from 19 countries. FAIR will be an accelerator facility leading the European research in nuclear and hadron physics in the coming decade.

  14. Antiproton radiation found effective in cancer research

    CERN Multimedia

    2003-01-01

    "An international collaboration of scientists has completed the first ever antiproton beam experiments designed to reveal the biological effectiveness of antiproton radiation in terminating cells used for cancer research...PBar Labs assembled the collaboration at CERN (European Organization for Nuclear Research in Geneva) to perform the measurements" (1 page).

  15. The biological effectiveness of antiproton irradiation

    DEFF Research Database (Denmark)

    Holzscheiter, Michael H.; Bassler, Niels; Agazaryan, Nzhde

    2006-01-01

    ever measurements of the biological effectiveness of antiprotons. Materials and methods: V79 cells were suspended in a semi-solid matrix and irradiated with 46.7 MeV antiprotons, 48 MeV protons, or 60Co c-rays. Clonogenic survival was determined as a function of depth along the particle beams. Dose...... and particle fluence response relationships were constructed from data in the plateau and Bragg peak regions of the beams and used to assess the biological effectiveness. Results: Due to uncertainties in antiproton dosimetry we defined a new term, called the biologically effective dose ratio (BEDR), which...... has a higher relative biological effectiveness (RBE). Conclusion: We have produced the first measurements of the biological consequences of antiproton irradiation. These data substantiate theoretical predictions of the biological effects of antiproton annihilation within the Bragg peak, and suggest...

  16. The relative biological effectiveness of antiprotons

    DEFF Research Database (Denmark)

    Holzscheiter, Michael H.; Alsner, Jan; Bassler, Niels

    2016-01-01

    Background and purpose: Aside from the enhancement of physical dose deposited by antiprotons annihilating in tissue-like material compared to protons of the same range a further increase of biological effective dose has been demonstrated. This enhancement can be expressed in an increase of the re......Background and purpose: Aside from the enhancement of physical dose deposited by antiprotons annihilating in tissue-like material compared to protons of the same range a further increase of biological effective dose has been demonstrated. This enhancement can be expressed in an increase...... of the relative biological effectiveness (RBE) of antiprotons near the end of range. We have performed the first-ever direct measurement of the RBE of antiprotons both at rest and in flight. Materials and methods: Experimental data were generated on the RBE of an antiproton beam entering a tissue-like target...

  17. Laser-driven ultrafast antiproton beam

    Science.gov (United States)

    Li, Shun; Pei, Zhikun; Shen, Baifei; Xu, Jiancai; Zhang, Lingang; Zhang, Xiaomei; Xu, Tongjun; Yu, Yong; Bu, Zhigang

    2018-02-01

    Antiproton beam generation is investigated based on the ultra-intense femtosecond laser pulse by using two-dimensional particle-in-cell and Geant4 simulations. A high-flux proton beam with an energy of tens of GeV is generated in sequential radiation pressure and bubble regime and then shoots into a high-Z target for producing antiprotons. Both yield and energy of the antiproton beam increase almost linearly with the laser intensity. The generated antiproton beam has a short pulse duration of about 5 ps and its flux reaches 2 × 10 20 s - 1 at the laser intensity of 2.14 × 10 23 W / cm 2 . Compared to conventional methods, this new method based on the ultra-intense laser pulse is able to provide a compact, tunable, and ultrafast antiproton source, which is potentially useful for quark-gluon plasma study, all-optical antihydrogen generation, and so on.

  18. Physics with antiprotons at LEAR

    International Nuclear Information System (INIS)

    Kilian, K.

    1984-01-01

    The low energy antiproton ring LEAR started to work at CERN in 1983. It provides clean anti p beams of much higher intensity and much better quality than available so far in the range from 0.1 to 2 GeV/c momentum. 16 of the 17 accepted experiments are installed and 14 of them took first data in 1983. After approx.= 240 hours of LEAR operation very first results are available. One can expect that exciting physics results be produced in many different domains provided LEAR gets enough anti p in the future. (orig.)

  19. The proton-antiproton collider

    International Nuclear Information System (INIS)

    Evans, L.

    1988-01-01

    The subject of this lecture is the CERN Proton-Antiproton (panti p) Collider, in which John Adams was intimately involved at the design, development, and construction stages. Its history is traced from the original proposal in 1966, to the first panti p collisions in the Super Proton Synchrotron (SPS) in 1981, and to the present time with drastically improved performance. This project led to the discovery of the intermediate vector boson in 1983 and produced one of the most exciting and productive physics periods in CERN's history. (orig.)

  20. Antiproton fast ignition for inertial confinement fusion

    International Nuclear Information System (INIS)

    Perkins, L.J.

    1999-01-01

    With 180 MJ/microg, antiprotons offer the highest stored energy per unit mass of any known entity. The use of antiprotons to promote fast ignition in an inertial confinement fusion (ICF) capsule and produce high target gains with only modest compression of the main fuel is investigated. Unlike standard fast ignition where the ignition energy is supplied by energetic, short pulse laser, the energy here is supplied through the ionization energy deposited when antiprotons annihilate at the center of a compressed fuel capsule. This can be considered in-situ fast ignition as it obviates the need for the external injection of the ignition energy. In the first of two candidate schemes, the antiproton package is delivered by a low-energy ion beam. In the second, autocatalytic scheme, the antiprotons are preemplaced at the center of the capsule prior to compression. In both schemes, the author estimates that ∼10 12 antiprotons are required to initiate fast ignition in a typical ICF capsule and show that incorporation of a thin, heavy metal shell is desirable to enhance energy deposition within the ignitor zone. In addition to eliminating the need for a second, energetic fast laser and vulnerable final optics, this scheme would achieve central ignition without reliance on laser channeling through halo plasma or Hohlraum debris. However, in addition to the practical difficulties of storage and manipulation of antiprotons at low energy, the other large uncertainty for the practicality of such a speculative scheme is the ultimate efficiency of antiproton production in an external, optimized facility. Estimates suggest that the electrical wall plug energy per pulse required for the separate production of the antiprotons is of the same order as that required for the conventional slow compression driver

  1. Antiprotonic Radioactive Atom for Nuclear Structure Studies

    International Nuclear Information System (INIS)

    Wada, M.; Yamazaki, Y.

    2005-01-01

    A future experiment to synthesize antiprotonic radioactive nuclear ions is proposed for nuclear structure studies. Antiprotonic radioactive nuclear atom can be synthesized in a nested Penning trap where a cloud of antiprotons is prestored and slow radioactive nuclear ions are bunch-injected into the trap. By observing of the ratio of π+ and π- produced in the annihilation process, we can deduce the different abundance of protons and neutrons at the surface of the nuclei. The proposed method would provide a unique probe for investigating the nuclear structure of unstable nuclei

  2. Testing Quantum Chromodynamics with Antiprotons

    Energy Technology Data Exchange (ETDEWEB)

    Brodsky, S.

    2004-10-21

    The antiproton storage ring HESR to be constructed at GSI will open up a new range of perturbative and nonperturbative tests of QCD in exclusive and inclusive reactions. I discuss 21 tests of QCD using antiproton beams which can illuminate novel features of QCD. The proposed experiments include the formation of exotic hadrons, measurements of timelike generalized parton distributions, the production of charm at threshold, transversity measurements in Drell-Yan reactions, and searches for single-spin asymmetries. The interactions of antiprotons in nuclear targets will allow tests of exotic nuclear phenomena such as color transparency, hidden color, reduced nuclear amplitudes, and the non-universality of nuclear antishadowing. The central tool used in these lectures are light-front Fock state wavefunctions which encode the bound-state properties of hadrons in terms of their quark and gluon degrees of freedom at the amplitude level. The freedom to choose the light-like quantization four-vector provides an explicitly covariant formulation of light-front quantization and can be used to determine the analytic structure of light-front wave functions. QCD becomes scale free and conformally symmetric in the analytic limit of zero quark mass and zero {beta} function. This ''conformal correspondence principle'' determines the form of the expansion polynomials for distribution amplitudes and the behavior of non-perturbative wavefunctions which control hard exclusive processes at leading twist. The conformal template also can be used to derive commensurate scale relations which connect observables in QCD without scale or scheme ambiguity. The AdS/CFT correspondence of large N{sub C} supergravity theory in higher-dimensional anti-de Sitter space with supersymmetric QCD in 4-dimensional space-time has important implications for hadron phenomenology in the conformal limit, including the nonperturbative derivation of counting rules for exclusive processes and

  3. Prospects for antiproton experiments at Fermilab

    International Nuclear Information System (INIS)

    Kaplan, Daniel M.

    2012-01-01

    Fermilab operates the world’s most intense antiproton source. Newly proposed experiments can use those antiprotons either parasitically during Tevatron Collider running or after the end of the Tevatron Collider program. For example, the annihilation of 5 to 8 GeV antiprotons is expected to yield world-leading sensitivities to hyperon rare decays and CP violation. It could also provide the world’s most intense source of tagged D 0 mesons, and thus the best near-term opportunity to study charm mixing and, via CP violation, to search for new physics. Other measurements that could be made include properties of the X(3872) and the charmonium system. An experiment using a Penning trap and an atom interferometer could make the world’s most precise measurement of the gravitational force on antimatter. These and other potential measurements using antiprotons offer a great opportunity for a broad and exciting physics program at Fermilab in the post-Tevatron era.

  4. Antiproton Induced Fission and Fragmentation of Nuclei

    CERN Multimedia

    2002-01-01

    The annihilation of slow antiprotons with nuclei results in a large highly localized energy deposition primarily on the nuclear surface. \\\\ \\\\ The study of antiproton induced fission and fragmentation processes is expected to yield new information on special nuclear matter states, unexplored fission modes, multifragmentation of nuclei, and intranuclear cascades.\\\\ \\\\ In order to investigate the antiproton-nucleus interaction and the processes following the antiproton annihilation at the nucleus, we propose the following experiments: \\item A)~Measurement of several fragments from fission and from multifragmentation in coincidence with particle spectra, especially neutrons and kaons. \\item B)~Precise spectra of $\\pi$, K, n, p, d and t with time-of-flight techniques. \\item C)~Installation of the Berlin 4$\\pi$ neutron detector with a 4$\\pi$ Si detector placed inside for fragments and charged particles. This yields neutron multiplicity distributions and consequently distributions of thermal excitation energies and...

  5. Antiproton chain of the FAIR storage rings

    International Nuclear Information System (INIS)

    Katayama, T; Kamerdzhiev, V; Lehrach, A; Maier, R; Prasuhn, D; Stassen, R; Stockhorst, H; Herfurth, F; Lestinsky, M; Litvinov, Yu A; Steck, M; Stöhlker, T

    2015-01-01

    In the Modularized Start Version of the Facility of Antiproton and Ion Research (FAIR) at Darmstadt Germany, the 3 GeV antiprotons are precooled in the collector ring and accumulated in the high energy storage ring (HESR). They are further accelerated to 14 GeV or decelerated to 1 GeV for the experiments with a high-density internal target. The powerful beam cooling devices, stochastic cooling and electron cooling will support the provision of a high-resolution antiproton beam. The other option of FAIR is to prepare the low energy, 300 keV antiproton beam connecting the existing storage rings ESR and CRYRING with HESR. Beam physics issues related with these concepts are described. (paper)

  6. ASACUSA measures microwave transition in antiprotonic helium

    CERN Document Server

    Eades, John

    2003-01-01

    The ASACUSA collaboration has reinforced its status as a paragon of precision physics by following up its impressive six parts in 10/sup 8/ measurement of the antiproton's charge and mass with new measurements of its magnetism. (4 refs).

  7. Experimental setup and first measurement of DNA damage induced along and around an antiproton beam

    International Nuclear Information System (INIS)

    Kavanagh, J.N.; Currell, F.J.; Prise, K.M.; Schettino, G.; Currell, F.J.; Timson, D.J.; Holzscheiter, M.H.; Bassler, N.; Herrmann, R.

    2010-01-01

    Radiotherapy employs ionizing radiation to induce lethal DNA lesions in cancer cells while minimizing damage to healthy tissues. Due to their pattern of energy deposition, better therapeutic outcomes can, in theory, be achieved with ions compared to photons. Antiprotons have been proposed to offer a further enhancement due to their annihilation at the end of the path. The work presented here aimed to establish and validate an experimental procedure for the quantification of plasmid and genomic DNA damage resulting from antiproton exposure. Immunocytochemistry was used to assess DNA damage in directly and indirectly exposed human fibroblasts irradiated in both plateau and Bragg peak regions of a 126 MeV antiproton beam at CERN. Cells were stained post irradiation with an anti-γ-H2AX antibody. Quantification of the γ-H2AX foci-dose relationship is consistent with a linear increase in the Bragg peak region. A qualitative analysis of the foci detected in the Bragg peak and plateau region indicates significant differences highlighting the different severity of DNA lesions produced along the particle path. Irradiation of desalted plasmid DNA with 5 Gy antiprotons at the Bragg peak resulted in a significant portion of linear plasmid in the resultant solution. (authors)

  8. CERN: Antiprotons probe the nuclear stratosphere

    International Nuclear Information System (INIS)

    Anon.

    1995-01-01

    The outer periphery of heavy stable nuclei is notoriously difficult to study experimentally. While the well understood electromagnetic interaction between electrons (or muons) and protons has given the nuclear charge (or proton) distribution with high precision for almost all stable nuclei, neutron distribution studies are much less precise. This is especially true for large nuclear distances, where the nuclear density is small. A few previous experiments probing the nuclear ''stratosphere'' suggested that far from the centre of the nucleus (of the order of 2 nuclear radii) this stratosphere may be composed predominantly of neutrons. At the end of the sixties the term ''neutron halo'' was introduced to describe this phenomenon, but experimental evidence was scarce or even controversial, and remained so for almost a quarter of a century. Recently, the Warsaw/Munich/Berlin collaboration working within the PS203 experiment at CERN's LEAR low energy antiproton ring, proposed a new method to study the nuclear periphery using stopped antiprotons. The halo now looks firmer. A 200 MeV/c beam of antiprotons was slowed down by interactions with atomic electrons. When antiproton kinetic energy drops well below 1 keV, the particles are captured in the outermost orbits of ''exotic atoms'', where the antiprotons take the place of the usual orbital electrons. With the lower orbits in this antiprotonic atom empty, the antiproton drops toward the nuclear surface, first emitting Auger electrons and later predominantly antiprotonic X-rays. Due to the strong interaction between antiprotons and nucleons, the antiproton succumbs to annihilation with a nucleon in the rarified nuclear stratosphere, far above the innermost Bohr orbit of the atom. The annihilation probability in heavy nuclei is maximal where the nuclear density is about 3% of its central value and extends to densities many orders of magnitude smaller

  9. CERN: Antiprotons probe the nuclear stratosphere

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1995-06-15

    The outer periphery of heavy stable nuclei is notoriously difficult to study experimentally. While the well understood electromagnetic interaction between electrons (or muons) and protons has given the nuclear charge (or proton) distribution with high precision for almost all stable nuclei, neutron distribution studies are much less precise. This is especially true for large nuclear distances, where the nuclear density is small. A few previous experiments probing the nuclear ''stratosphere'' suggested that far from the centre of the nucleus (of the order of 2 nuclear radii) this stratosphere may be composed predominantly of neutrons. At the end of the sixties the term ''neutron halo'' was introduced to describe this phenomenon, but experimental evidence was scarce or even controversial, and remained so for almost a quarter of a century. Recently, the Warsaw/Munich/Berlin collaboration working within the PS203 experiment at CERN's LEAR low energy antiproton ring, proposed a new method to study the nuclear periphery using stopped antiprotons. The halo now looks firmer. A 200 MeV/c beam of antiprotons was slowed down by interactions with atomic electrons. When antiproton kinetic energy drops well below 1 keV, the particles are captured in the outermost orbits of ''exotic atoms'', where the antiprotons take the place of the usual orbital electrons. With the lower orbits in this antiprotonic atom empty, the antiproton drops toward the nuclear surface, first emitting Auger electrons and later predominantly antiprotonic X-rays. Due to the strong interaction between antiprotons and nucleons, the antiproton succumbs to annihilation with a nucleon in the rarified nuclear stratosphere, far above the innermost Bohr orbit of the atom. The annihilation probability in heavy nuclei is maximal where the nuclear density is about 3% of its central value and extends to densities many orders of magnitude smaller. Antiproton annihilation on a proton or on a neutron at the nuclear

  10. Physics with ultra-low energy antiprotons

    International Nuclear Information System (INIS)

    Holtkamp, D.B.; Holzscheiter, M.H.; Hughes, R.J.

    1989-01-01

    The experimental observation that all forms of matter experience the same gravitational acceleration is embodied in the weak equivalence principle of gravitational physics. However no experiment has tested this principle for particles of antimatter such as the antiproton or the antihydrogen atom. Clearly the question of whether antimatter is in compliance with weak equivalence is a fundamental experimental issue, which can best be addressed at an ultra-low energy antiproton facility. This paper addresses the issue. 20 refs

  11. Information on antiprotonic atoms and the nuclear periphery from the PS209 experiment

    CERN Document Server

    Trzcinska, A.; Czosnyka, T.; von Egidy, T.; Gulda, K.; Hartmann, F.J.; Iwanicki, J.; Ketzer, B.; Kisielinski, M.; Klos, B.; Kurcewicz, W.; Lubinski, P.; Napiorkowski, P.J.; Pienkowski, L.; Schmidt, R.; Widmann, E.

    2001-01-01

    In the PS209 experiments at CERN two kinds of measurements were performed: the in-beam measurement of X-rays from antiprotonic atoms and the radiochemical, off-line determination of the yield of annihilation products with mass number A_t -1 (less by 1 than the target mass). Both methods give observables which allows to study the peripheral matter density composition and distribution.

  12. Evidence For The Production Of Slow Antiprotonic Hydrogen In Vacuum

    CERN Document Server

    Zurlo, N.; Amsler, C.; Bonomi, G.; Carraro, C.; Cesar, C.L.; Charlton, M.; Doser, M.; Fontana, A.; Funakoshi, R.; Genova, P.; Hayano, R.S.; Jorgensen, L.V.; Kellerbauer, A.; Lagomarsino, V.; Landua, R.; Lodi Rizzini, E.; Macri, M.; Madsen, N.; Manuzio, G.; Mitchard, D.; Montagna, P.; Posada, L.G.; Pruys, H.; Regenfus, C.; Rotondi, A.; Testera, G.; der Werf, D.P.Van; Variola, A.; Venturelli, L.; Yamazaki, Y.

    2006-01-01

    We present evidence showing how antiprotonic hydrogen, the quasistable antiproton-proton (pbar-p) bound system, has been synthesized following the interaction of antiprotons with the hydrogen molecular ion (H2+) in a nested Penning trap environment. From a careful analysis of the spatial distributions of antiproton annihilation events, evidence is presented for antiprotonic hydrogen production with sub-eV kinetic energies in states around n=70, and with low angular momenta. The slow antiprotonic hydrogen may be studied using laser spectroscopic techniques.

  13. The antiproton depth–dose curve in water

    CERN Document Server

    Bassler, N; Jäkel, O; Knudsen, H V; Kovacevic, S

    2008-01-01

    We have measured the depth–dose curve of 126 MeV antiprotons in a water phantom using ionization chambers. Since the antiproton beam provided by CERN has a pulsed structure and possibly carries a high-LET component from the antiproton annihilation, it is necessary to correct the acquired charge for ion recombination effects. The results are compared with Monte Carlo calculations and were found to be in good agreement. Based on this agreement we calculate the antiproton depth–dose curve for antiprotons and compare it with that for protons and find a doubling of the physical dose in the peak region for antiprotons.

  14. Antiproton-nucleus potentials from global fits to antiprotonic X-rays and radiochemical data

    Czech Academy of Sciences Publication Activity Database

    Friedman, E.; Gal, A.; Mareš, Jiří

    2005-01-01

    Roč. 761, 3/4 (2005), s. 283-295 ISSN 0375-9474 R&D Projects: GA AV ČR IAA1048305 Institutional research plan: CEZ:AV0Z10480505 Keywords : antiproton-nuclear interaction * RMF calculations * antiproton X-rays Subject RIV: BE - Theoretical Physics Impact factor: 1.950, year: 2005

  15. Antiprotons four times more effective than protons for cell irradiation

    CERN Multimedia

    2006-01-01

    "A pioneering experiment at CERN with potential future application in cancer therapy has produced its first results. Started in 2003, ACE (Antiproton Cell Experiment) is the first investigation of the biological effects of antiprotons." (1,5 page)

  16. Antiprotons four times more effective than protons for cell irradiation

    CERN Multimedia

    2007-01-01

    "A pioneering experiment at CERN with potential future application in cancer therapy has produced its first results. Started in 2003, ACE (Antiproton Cell Experiment) is the first investigation of the biological effects of antiprotons." (1,5 page)

  17. The PANDA experiment: Antiproton physics at FAIR

    International Nuclear Information System (INIS)

    Montagna, P.

    2011-01-01

    The new Facility for Antiproton and Ion Research (FAIR), under construction at the GSI laboratory at Darmstadt, in a few years will make available, among different types of beams, even antiproton beams with unique features. Through a High Energy Storage Ring (HESR) for antiprotons, an antiproton beam will be available in a momentum range from 1.5 to 15 GeV/c, which will interact on a hydrogen target. The products of the interaction, including hadronic systems with strangeness and/or charm, will be detected with the PANDA magnetic spectrometer (antiProton ANnihilation at DArmstadt), and the spectroscopic analysis will allow a detailed investigation on a number of open problems of the hadronic physics, as the quark confinement, the existence of non-conventional meson states (so-called glueballs and hybrids), the structure of hadrons and of the strong interaction, with particular attention to charmonium spectroscopy. An overview of the scientific program of PANDA and the current status of the project will be presented.

  18. The Antiproton Depth-Dose Curve in Water

    DEFF Research Database (Denmark)

    Bassler, Niels; Holzscheiter, Michael; Jäkel, Oliver

    2008-01-01

    We have measured the depth-dose curve of 126 MeV antiprotons in a water phantom using ionization chambers. Since the antiproton beam provided by CERN has a pulsed structure and possibly carries a high-LET component from the antiproton annihilation, it is necessary to correct the acquired charge...

  19. Peripheral dose measurements with diode and thermoluminescence dosimeters for intensity modulated radiotherapy delivered with conventional and un-conventional linear accelerator

    International Nuclear Information System (INIS)

    Kinhikar, Rajesh; Tambe, Chandrashekhar; Kadam, Sudarshan; Deshpande, Deepak; Gamre, Poonam; Biju, George; Suryaprakash; Magai, C.S.; Shrivastava, Shyam; Dhote, Dipak

    2013-01-01

    The objective of this paper was to measure the peripheral dose (PD) with diode and thermoluminescence dosimeter (TLD) for intensity modulated radiotherapy (IMRT) with linear accelerator (conventional LINAC), and tomotherapy (novel LINAC). Ten patients each were selected from Trilogy dual-energy and from Hi-Art II tomotherapy. Two diodes were kept at 20 and 25 cm from treatment field edge. TLDs (LiF:MgTi) were also kept at same distance. TLDs were also kept at 5, 10, and 15 cm from field edge. The TLDs were read with REXON reader. The readings at the respective distance were recorded for both diode and TLD. The PD was estimated by taking the ratio of measured dose at the particular distance to the prescription dose. PD was then compared with diode and TLD for LINAC and tomotherapy. Mean PD for LINAC with TLD and diode was 2.52 cGy (SD 0.69), 2.07 cGy (SD 0.88) at 20 cm, respectively, while at 25 cm, it was 1.94 cGy (SD 0.58) and 1.5 cGy (SD 0.75), respectively. Mean PD for tomotherapy with TLD and diode was 1.681 cGy (SD 0.53) and 1.58 (SD 0.44) at 20 cm, respectively. The PD was 1.24 cGy (SD 0.42) and 1.088 cGy (SD 0.35) at 25 cm, respectively, for tomotherapy. Overall, PD from tomotherapy was found lower than LINAC by the factor of 1.2-1.5 PD measurement is essential to find out the potential of secondary cancer. PD for both (conventional LINAC) and novel LINACs (tomotherapy) were measured and compared with each other. The comparison of the values for PD presented in this work and those published in the literature is difficult because of the different experimental conditions. The diode and TLD readings were reproducible and both the detector readings were comparable. (author)

  20. Antiproton Production beam and Reverse Injection System

    Energy Technology Data Exchange (ETDEWEB)

    Chadwick, G.

    1981-08-16

    The objectives of this project are two fold: (1) To extract high energy protons from the Main Ring (MR) and target them to produce antiprotons which are subsequently captured in the existing Booster accelerator; and (2) to provide a channel for injecting either protons or antiprotons into the MR from the booster in a direction opposite to that of the normal proton acceleration as colliding beams can be created. The present design, therefore, is in support of two separate larger projects, viz., the collisions of protons in the Tevatron (normal circulation direction) with 'reverse injected' protons in the MR, and the collision of normal direction protons with reverse injected antiprotons either in the MR or in the Tevatron. Figure 1 shows the layout of the project area. It spans the shortest distance between possible injection/ejection points in the existing accelerator structures, hence minimizing costs. The tunnel will lie underground at the level of the MR and booster.

  1. The Antiproton and How It Was Discovered

    International Nuclear Information System (INIS)

    Eades, John

    2005-01-01

    The antiproton celebrates its 50th birthday this year. Although its existence had been suspected since the discovery of the positron in 1932, there was still doubt in some quarters that such a companion particle to the proton could exist. I will try to trace the scientific history of the antiproton from that time to the publication of the definitive paper by Chamberlain, Segre, Wiegand and Ypsilantis in November 1955, with a brief look at what happened next. The narrative will be supplemented with thoughts and opinions of some of the main actors, both at the time and in retrospect

  2. Evaporative Cooling of Antiprotons to Cryogenic Temperatures

    CERN Document Server

    Andresen, G B; Baquero-Ruiz, M; Bertsche, W; Bowe, P D; Butler, E; Cesar, C L; Chapman, S; Charlton, M; Fajans, J; Friesen, T; Fujiwara, M C; Gill, D R; Hangst, J S; Hardy, W N; Hayano, R S; Hayden, M E; Humphries, A; Hydomako, R; Jonsell, S; Kurchaninov, L; Lambo, R; Madsen, N; Menary, S; Nolan, P; Olchanski, K; Olin, A; Povilus, A; Pusa, P; Robicheaux, F; Sarid, E; Silveira, D M; So, C; Storey, J W; Thompson, R I; van der Werf, D P; Wilding, D; Wurtele, J S; Yamazaki, Y

    2010-01-01

    We report the application of evaporative cooling to clouds of trapped antiprotons, resulting in plasmas with measured temperature as low as 9~K. We have modeled the evaporation process for charged particles using appropriate rate equations. Good agreement between experiment and theory is observed, permitting prediction of cooling efficiency in future experiments. The technique opens up new possibilities for cooling of trapped ions and is of particular interest in antiproton physics, where a precise CPT test on trapped antihydrogen is a long-standing goal.

  3. K-shell ionization by antiprotons

    International Nuclear Information System (INIS)

    Mehler, G.; Mueller, B.; Greiner, W.; Soff, G.

    1987-01-01

    We present first calculations for the impact parameter dependence of K-shell ionization rates in anti pCu and in anti pAg collisions at various projectile energies. We show that the effect of the attractive Coulomb potential on the Rutherford trajectory and the anti-binding effect caused by the negative charge of the antiproton result in a considerable increase of the ionization probability. Total ionization cross-sections for proton and antiproton projectiles are compared with each other and with experimental ionization cross-sections for protons. (orig.)

  4. Collisions involving antiprotons and antihydrogen: an overview

    Science.gov (United States)

    Jonsell, S.

    2018-03-01

    I give an overview of experimental and theoretical results for antiproton and antihydrogen scattering with atoms and molecules (in particular H, He). At low energies (>1 keV) there are practically no experimental data available. Instead I compare the results from different theoretical calculations, of various degrees of sophistication. At energies up to a few tens of eV, I focus on simple approximations that give reasonably accurate results, as these allow quick estimates of collision rates without embarking on a research project. This article is part of the Theo Murphy meeting issue `Antiproton physics in the ELENA era'.

  5. Peripheral neuropathy

    Science.gov (United States)

    ... peripheral; Neuritis - peripheral; Nerve disease; Polyneuropathy; Chronic pain - peripheral neuropathy ... Philadelphia, PA: Elsevier; 2016:chap 107. Shy ME. Peripheral neuropathies. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  6. The ASACUSA experiment at CERN's AD antiproton decelerator catches antiprotons in helium, where the antiprotons replace electrons, giving exotics atoms.

    CERN Multimedia

    Loïez, P

    2000-01-01

    Photo 03: Laser beams are prepared for shooting at antiprotonic helium atoms. Left to right: Masaki Hori (Tokyo University) and John Eades (CERN). Photo 01: Dye laser triggered by "YAG" laser. Photo 02: Masaki Hori adjusting optical system of laser beams.

  7. Some preliminary considerations on antiproton-nucleus experiments

    International Nuclear Information System (INIS)

    Yavin, A.I.

    1981-05-01

    The antiproton as a probe of the atomic nucleus is discussed in the expectation that fairly intense beams of high quality will be available in 1983 at the Low Energy Antiproton Ring (LEAR) facility at CERN and possibly also in some other laboratories at a later date. Several antiproton-nucleus experiments are proposed, and the possibility of observing antiprotonic nuclei as well as antineutronic nuclei is discussed. It is demonstrated that even for the study of the elementary nucleon-antinucleon systems it could be advantageous to use nuclei rather than protons as target. The possibility of investigating several antiprotonic atomic systems is also briefly discussed [fr

  8. Recent progress of laser spectroscopy experiments on antiprotonic helium

    Science.gov (United States)

    Hori, Masaki

    2018-03-01

    The Atomic Spectroscopy and Collisions Using Slow Antiprotons (ASACUSA) collaboration is currently carrying out laser spectroscopy experiments on antiprotonic helium ? atoms at CERN's Antiproton Decelerator facility. Two-photon spectroscopic techniques have been employed to reduce the Doppler width of the measured ? resonance lines, and determine the atomic transition frequencies to a fractional precision of 2.3-5 parts in 109. More recently, single-photon spectroscopy of buffer-gas cooled ? has reached a similar precision. By comparing the results with three-body quantum electrodynamics calculations, the antiproton-to-electron mass ratio was determined as ?, which agrees with the known proton-to-electron mass ratio with a precision of 8×10-10. The high-quality antiproton beam provided by the future Extra Low Energy Antiproton Ring (ELENA) facility should enable further improvements in the experimental precision. This article is part of the Theo Murphy meeting issue `Antiproton physics in the ELENA era'.

  9. The Antiproton-Ion-Collider at FAIR

    International Nuclear Information System (INIS)

    Kruecken, R.; Fabbietti, L.; Faestemann, T.; Homolka, J.; Kienle, P.; Ring, P.; Suzuki, K.; Bosch, F.; Franzke, B.; Kozhuharov, Ch.; Litvinov, Y.; Nolden, F.; Cargnelli, M.; Fuhrmann, H.; Hirtl, A.; Marton, J.; Widmann, E.; Zmeskal, J.; Hayano, R. S.; Lenske, H.

    2006-01-01

    An antiproton-ion collider (AIC) has been proposed for the FAIR Project at Darmstadt to independently determine rms radii for protons and neutrons in stable and short lived nuclei by means of antiproton annihilation at medium energies. The AIC makes use of the ELISe electron ion collider complex to store, cool and collide antiprotons of 30 MeV energy with short lived radioactive ions in the NESR. The exotic nuclei are produced by projectile fragmentation or projectile fission and separated in the Super FRS. By detecting the loss of stored ions using the Schottky method the total absorption cross-section for antiprotons on the stored ions with mass A will be measured. Cross sections for the absorption on protons and neutrons, respectively, will be measured by the detection of residual nuclei with A-1 either by the Schottky method or by detecting them in recoil detectors after the first dipole stage of the NESR following the interaction zone. The absorption cross sections are in first order directly proportional to the mean square radii

  10. Low energy antiproton experiments - A review

    NARCIS (Netherlands)

    Jungmann, KP; Yamazaki, Y; Wada, M

    2005-01-01

    Low energy antiprotons offer excellent opportunities to study properties of fundamental forces and symmetries in nature. Experiments with them can contribute substantially to deepen our fundamental knowledge in atomic, nuclear and particle physics. Searches for new interactions can be carried out by

  11. Antiprotons in the CERN intersecting storage rings

    International Nuclear Information System (INIS)

    Bryant, P.J.

    1984-01-01

    High-sensitivity electronics for TTl and ring 2 had been developed and installed, the original experimental stochastic cooling systems in the ISR were rebuilt and considerably improved, the split-field magnet (SFM) vacuum chamber was modified, some steering dipoles were designed, made and installed, and finally innumerable interlocks and computer programs were revised for antiproton operation. (orig./HSI)

  12. Collisions of antiprotons with hydrogen molecular ions

    DEFF Research Database (Denmark)

    Lühr, Armin Christian; Saenz, Alejandro

    2009-01-01

    Time-dependent close-coupling calculations of the ionization and excitation cross section for antiproton collisions with molecular hydrogen ions are performed in an impact energy range from 0.5 keV to 10 MeV. The Born-Oppenheimer and Franck-Condon approximations as well as the impact parameter...

  13. A naturally occurring trap for antiprotons

    International Nuclear Information System (INIS)

    Eades, J.; Morita, N.; Ito, T.M.

    1993-05-01

    The phenomenon of delayed annihilation of antiprotons in helium is the first instance of a naturally occurring trap for antimatter in ordinary matter. Recent studies of this effect at CERN are summarized, and plans are described for laser excitation experiments to test its interpretation in terms of metastable exotic helium atom formation. (author)

  14. Recent results from proton-antiproton colliders

    International Nuclear Information System (INIS)

    Geer, S.

    1990-03-01

    New results from the CERN and Fermilab proton-antiproton colliders are summarised. The areas covered are jet physics, direct photon production, W and Z production and decay, heavy flavor production, the search for the top quark, and the search for more exotic phenomena. 46 refs., 20 figs., 4 tabs

  15. Calculated LET-Spectrum of Antiprotons

    DEFF Research Database (Denmark)

    Bassler, Niels

    -LET components resulting from the annihilation. Though, the calculations of dose-averaged LET in the entry region may suggest that the RBE of antiprotons in the plateau region could significantly differ from unity. Materials and Methods Monte Carlo simulations using FLUKA were performed for calculating...

  16. Conceptual Design of an Antiproton Generation and Storage Facility

    Energy Technology Data Exchange (ETDEWEB)

    Peggs, Stephen

    2006-10-24

    The Antiproton Generation and Storage Facility (AGSF) creates copious quantities of antiprotons, for bottling and transportation to remote cancer therapy centers. The first step in the generation and storage process is to accelerate an intense proton beam down the Main Linac for injection into the Main Ring, which is a Rapid Cycling Synchrotron that accelerates the protons to high energy. The beam is then extracted from the ring into a transfer line and into a Proton Target. Immediately downstream of the target is an Antiproton Collector that captures some of the antiprotons and focuses them into a beam that is transported sequentially into two antiproton rings. The Precooler ring rapidly manipulates antiproton bunches from short and broad (in momentum) to long and thin. It then performs some preliminary beam cooling, in the fraction of a second before the next proton bunch is extracted from the Main Ring. Pre-cooled antiprotons are passed on to the Accumulator ring before the next antiprotons arrive from the target. The Accumulator ring cools the antiprotons, compressing them into a dense state that is convenient for mass storage over many hours. Occasionally the Accumulator ring decelerates a large number of antiprotons, injecting them into a Deceleration Linac that passes them into a waiting Penning trap.

  17. Conceptual Design of an Antiproton Generation and Storage Facility

    International Nuclear Information System (INIS)

    Peggs, Stephen

    2006-01-01

    The Antiproton Generation and Storage Facility (AGSF) creates copious quantities of antiprotons, for bottling and transportation to remote cancer therapy centers. The first step in the generation and storage process is to accelerate an intense proton beam down the Main Linac for injection into the Main Ring, which is a Rapid Cycling Synchrotron that accelerates the protons to high energy. The beam is then extracted from the ring into a transfer line and into a Proton Target. Immediately downstream of the target is an Antiproton Collector that captures some of the antiprotons and focuses them into a beam that is transported sequentially into two antiproton rings. The Precooler ring rapidly manipulates antiproton bunches from short and broad (in momentum) to long and thin. It then performs some preliminary beam cooling, in the fraction of a second before the next proton bunch is extracted from the Main Ring. Pre-cooled antiprotons are passed on to the Accumulator ring before the next antiprotons arrive from the target. The Accumulator ring cools the antiprotons, compressing them into a dense state that is convenient for mass storage over many hours. Occasionally the Accumulator ring decelerates a large number of antiprotons, injecting them into a Deceleration Linac that passes them into a waiting Penning trap

  18. Deceleration of Antiprotons in Support of Antiproton Storage/Utilization Research

    International Nuclear Information System (INIS)

    Howe, Steven D.; Jackson, Gerald P.; Pearson, J. Boise; Lewis, Raymond A.

    2005-01-01

    Antimatter has the highest energy density known to mankind. Many concepts have been studied that use antimatter for propulsion. All of these concepts require the development of high density storage. H-bar Technologies, under contract with the NASA Marshall Space Flight Center, has undertaken the first step toward development of high density storage. Demonstration of the ability to store antiprotons in a Penning Trap provides the technology to pursue research in alternative storage methods that may lead to eventually to high density concepts. H-bar Technologies has undertaken research activity on the detailed design and operations required to decelerate and redirect the Fermi National Accelerator Laboratory (FNAL) antiproton beam to lay the groundwork for a source of low energy antiprotons. We have performed a detailed assessment of an antiproton deceleration scheme using the FNAL Main Injector, outlining the requirements to significantly and efficiently lower the energy of antiprotons. This task shall require a combination of: theoretical/computation simulations, development of specialized accelerator controls programming, modification of specific Main Injector hardware, and experimental testing of the modified system. Testing shall be performed to characterize the system with a goal of reducing the beam momentum from 8.9 GeV/c to a level of 1 GeV/c or less. We have designed an antiproton degrader system that will integrate with the FNAL decelerated/transferred beam. The degrader shall be designed to maximize the number of low energy antiprotons with a beam spot sized for acceptance by the Mark I test hardware

  19. Two-photon laser spectroscopy of antiprotonic helium and the antiproton-to-electron mass ratio

    CERN Document Server

    Hori, Masaki; Barna, Daniel; Andreas Dax,; Hayano, Ryugo; Friedreich, Susanne; Juhász, Bertalan; Pask, Thomas; Widmann, Eberhard; Horváth, Dezső; Venturelli, Luca; Zurlo, Nicola; 10.1038/nature10260

    2013-01-01

    Physical laws are believed to be invariant under the combined transformations of charge, parity and time reversal (CPT symmetry). This implies that an antimatter particle has exactly the same mass and absolute value of charge as its particle counterpart. Metastable antiprotonic helium ($\\bar{p}He^+$) is a three-body atom2 consisting of a normal helium nucleus, an electron in its ground state and an antiproton ($\\bar{p}$) occupying a Rydberg state with high principal and angular momentum quantum numbers, respectively n and l, such that n ≈ l + 1 ≈ 38. These atoms are amenable to precision laser spectroscopy, the results of which can in principle be used to determine the antiproton-to-electron mass ratio and to constrain the equality between the antiproton and proton charges and masses. Here we report two-photon spectroscopy of antiprotonic helium, in which $\\bar{p}^{3}He^{+}$ and $\\bar{p}^{4}He^{+}$ isotopes are irradiated by two counter-propagating laser beams. This excites nonlinear, two-phot...

  20. CERN accelerator school: Antiprotons for colliding beam facilities

    International Nuclear Information System (INIS)

    Bryant, P.; Newman, S.

    1984-01-01

    This is a specialized course which addresses a wide spectrum of theoretical and technological problems confronting the designer of an antiproton facility for high-energy-physics research. A broad and profound basis is provided by the lecturers' substantial experience gained over many years with CERN's unique equipment. Topics include beam optics, special lattices for antiproton accumulation and storage rings, antiproton production, stochastic cooling, acceleration and storage, r.f. noise, r.f. beam manipulations, beam-beam interaction, beam stability due to ion accumulation, and diagnostics. The SPS (Super Proton Synchrotron) panti p collider, LEAR (the Low Energy Antiproton Ring at CERN), antiprotons in the ISR (Intersecting Storage Rings), the new antiproton collector (ACOL) and gas jet targets are also discussed. A table is included listing the parameters of all CERN's accelerators and storage rings. See hints under the relevant topics. (orig./HSI)

  1. Beam position pickup for antiprotons to the ISR

    CERN Multimedia

    CERN PhotoLab

    1981-01-01

    The Antiproton Project, launched for proton-antiproton collisions in the SPS (SPS collider), had a side-line for p-pbar collisions in the ISR. A new transfer line, TT6, was constructed to transport antiprotons from the 26 GeV PS to the injection line TT1 of ISR ring 2. Antiprotons were a scarce commodity. For setting up the lines, beam diagnostic devices in the antiproton path had to work reliably and precisely with just a few low-intensity pilot pules: single bunches of about 2x10**9 antiprotons every few hours. Electrostatic pickup electrodes were used to measure beam position. They could be mounted for measurement in the horizontal plane, as in this picture, or at 90 deg, for the vertical plane.

  2. Antiproton rate estimates for the 1996 E866 experiment

    International Nuclear Information System (INIS)

    Shea, J.Y.; Garcia-Solis, E.J.; Stanskas, P.J.

    1996-01-01

    There has always been a strong interest to study antiprotons produced in relativistic heavy ion collisions. A specific point has been a puzzle for years in that both ARC and RQMD predict the correct antiproton yield for Au+Au collisions at the AGS, but with two entirely different physical explanations. The RQMD is able to describe available data by relying on the enhanced production of antiprotons, followed by the annihilation of a large fraction of the produced antiprotons. Conversely, ARC describes the data by producing less antiprotons initially, but the annihilation of the antiprotons is open-quotes screenedclose quotes in the high density environment of the collision on account of collisions with mesons. It is then particularly interesting to studying the shadowing effect in the Au-Au collisions at the AGS to shine a light in the theoretical debate in heavy-ion collisions

  3. Antiproton Powered Gas Core Fission Rocket

    International Nuclear Information System (INIS)

    Kammash, Terry

    2005-01-01

    Extensive research in recent years has demonstrated that 'at rest' annihilation of antiprotons in the uranium isotope U238 leads to fission at nearly 100% efficiency. The resulting highly-ionizing, energetic fission fragments can heat a suitable medium to very high temperatures, making such a process particularly suitable for space propulsion applications. Such an ionized medium, which would serve as a propellant, can be confined by a magnetic field during the heating process, and subsequently ejected through a magnetic nozzle to generate thrust. The gasdynamic mirror (GDM) magnetic configuration is especially suited for this application since the underlying confinement principle is that the plasma be of such density and temperature as to make the ion-ion collision mean free path shorter than the plasma length. Under these conditions the plasma behaves like a fluid, and its escape from the system is analogous to the flow of a gas into vacuum from a vessel with a hole. For the system we propose we envisage radially injecting atomic or U238 plasma beam at a pre-determined position and axially pulsing an antiproton beam which upon interaction with the uranium target gives rise to near isotropic ejection of fission fragments with a total mass of 212 amu and total energy of about 160 MeV. These particles, along with the annihilation products (i.e. pions and muons) will heat the background U238 gas - inserted into the chamber just prior to the release of the antiproton - to one keV temperature. Preliminary analysis reveals that such a propulsion system can produce a specific impulse of about 3000 seconds at a thrust of about 50 kN. When applied to a round trip Mars mission, we find that such a journey can be accomplished in about 142 days with 2 days of thrusting and requiring only one gram of antiprotons to achieve it

  4. Magnetic horn of the Antiproton Accumulator (AA)

    CERN Multimedia

    Photographic Service

    1988-01-01

    In the 1960s, the invention of this "current sheet lens" has helped to greatly improve the flux of neutrino beams. It was used again at the AA, collecting antiprotons from the production target at angles too large to fit into the acceptance of the AA. It was machined from aluminium to a thickness of 1.4 mm and pulsed at 400 kA for 15 microseconds (half-sine).

  5. Looking for new gravitational forces with antiprotons

    International Nuclear Information System (INIS)

    Nieto, M.M.; Bonner, B.E.

    1987-01-01

    Quite general arguments based on the principle of equivalence and modern field theory show that it is possible for the gravitational acceleration of antimatter to be different than that for matter. Further, there is no experimental evidence to rule out the possibility. In fact, some evidence indicates there may be unexpected effects. Thus, the planned experiment to measure the gravitational acceleration of antiprotons is of fundamental importance. 20 refs., 3 figs

  6. Reliability of the Fermilab Antiproton Source

    International Nuclear Information System (INIS)

    Harms, E. Jr.

    1993-05-01

    This paper reports on the reliability of the Fermilab Antiproton source since it began operation in 1985. Reliability of the complex as a whole as well as subsystem performance is summarized. Also discussed is the trending done to determine causes of significant machine downtime and actions taken to reduce the incidence of failure. Finally, results of a study to detect previously unidentified reliability limitations are presented

  7. Potential kaon and antiproton beams at BNL

    International Nuclear Information System (INIS)

    Lazarus, D.M.

    1991-01-01

    The AGS at Brookhaven is the worlds most prolific producer of kaons and low energy antiprotons during operations. With the imminent operation of the AGS Booster which will increase intensities by an anticipated factor of six in the next few years, it will become possible to have purified beams of particles containing strange quarks and anti-quarks with intensities comparable to the pion beams which have so successfully dominated precision hadron spectroscopy in the past. 10 refs., 3 figs

  8. A new approach to experiments with non-relativistic antiprotons

    International Nuclear Information System (INIS)

    Poth, H.

    1990-05-01

    Is low-energy antiproton physics phasing out with the present round of experiments or are there good reasons to continue at an improved slow antiproton facility which could be located at a high intensity hadron accelerator? We point out, that there are four frontiers where substantial advances could be made. In particular, we discuss the low-energy frontier and emphasize that experiments with no-relativistic antiprotons would increase drastically the sensitivity and would reveal new effects. (orig.)

  9. Measuring and manipulating an accumulated stack of antiprotons in the CERN antiproton accumulator

    International Nuclear Information System (INIS)

    Johson, R.; van der Meer, S.; Pederson, F.

    1983-01-01

    The antiproton stack is observed through Schottky scans, both longitudinal and transverse. A particular feature is the wide dynamic range needed for observing both the dense core and the freshly-deposited tail. Separating batches of antiprotons from the stack (unstacking) is a highly automated process including the measurement of the momentum distribution and the generation of a suitable RF function to remove a slice of the desired density. Multiple slices may be removed successively and a process for locally flattening the distribution to obtain equal batch intensities is used. When successive batches are unstacked and ejected, the process may have to be aborted if the particles do not arrive correctly at the user. A ''restack'' facility is provided to return any antiprotons to the stack that have been unstacked but not ejected. A missing-bucket scheme for unstacking low-intensity batches for LEAR is also described

  10. An analytical simulation of the ion-antiproton instabilities in the CERN Antiproton Accumulator

    International Nuclear Information System (INIS)

    Dainelli, A.; Pusterla, M.

    1988-01-01

    A direct map method with a Mathieu approach to tune modulation is proposed and used to simulate nonlinear effects on particle motion that are generated by a beam-beam-like interaction of antiprotons with ions of the residual gas in the CERN Antiproton Accumulator. Two different Gaussian ion distributions are used, and the effects of the simulated beam-beam force on the particle motion is studied in phase space, with a particular attention to high-order nonlinear resonances. (author) 16 refs., 4 figs

  11. Relationship between in vitro chromosomal radiosensitivity of peripheral blood lymphocytes and the expression of normal tissue damage following radiotherapy for breast cancer

    International Nuclear Information System (INIS)

    Barber, J.B.P.; Burrill, W.; Spreadborough, A.R.; Levine, E.; Warren, C.; Scott, D.; Kiltie, A.E.; Roberts, S.A.

    2000-01-01

    There is a need for rapid and reliable tests for the prediction of normal tissue responses to radiotherapy, as this could lead to individualization of patient radiotherapy schedules and thus improvements in the therapeutic ratio. Because the use of cultured fibroblasts is too slow to be practicable in a clinical setting, we evaluated the predictive role of assays of lymphocyte chromosomal radiosensitivity in patients having radiotherapy for breast cancer. Radiosensitivity was assessed using a macronucleus (MN) assay at high dose rate (HDR) and low dose rate (LDR) on lymphocytes irradiated in the G 0 phase of the cell cycle (Scott D, Barber JB, Levine EL, Burril W, Roberts SA. Radiation-induced micronucleus induction in lymphocytes identifies a frequency of radiosensitive cases among breast cancer patients: a test for predisposition? Br. J. Cancer 1998;77;614-620) and an assay of G 2 phase chromatid radiosensitivity ('G 2 assay') (Scott D, Spreadborough A, Levine E, Roberts SA. Genetic predisposition in breast cancer. Lancet 1994; 344: 1444). In a study of acute reactions, blood samples were taken from breast cancer patients before the start of radiotherapy, and the skin reaction documented. 116 patients were tested with the HDR MN assay, 73 with the LDR MN assay and 123 with the G 2 assay. In a study of late reactions, samples were taken from a series of breast cancer patients 8-14 years after radiotherapy and the patients assessed for the severity of late effects according to the 'LENT SOMA' scales. 47 were tested with the HDR assay, 26 with the LDR assay and 19 with the G 2 assay. For each clinical endpoint, patients were classified as being normal reactors or 'highly radiosensitive patients' (HR patients (Burnet NG. Johansen J, Turesson I, Nyman J. Describing patients' normal tissue reactions: Concerning the possibility of individualising radiotherapy dose prescriptions based on potential predictive assays of normal tissue radiosensitivity. Int. J. Cancer 1998

  12. Physics with antiprotons: from antihydrogen to the top-quark

    International Nuclear Information System (INIS)

    Koch, H.

    2001-01-01

    The talk gives a survey on experiments performed with antiprotons of different energies. The emphasis will be on results obtained at LEAR/CERN, but the exciting investigations with higher energy antiprotons, leading to the discovery of the intermediate bosons W + , W - , Z 0 and the top quark t, will also be discussed. (orig.)

  13. Serach for polarization effects in the antiproton production process

    CERN Multimedia

    It is proposed to study polarization effects in the production of antiprotons at the PS test beam line T11 at 3.5 GeV/c momentum. A polarization in the production process has never been studied but if existing it would allow for a rather simple and cheap way to generate a polarized antiproton beam with the existing facilities at CERN.

  14. Antiproton impact ionization of atomic hydrogen and helium

    Energy Technology Data Exchange (ETDEWEB)

    McGovern, M; Walters, H R J [Department of Applied Mathematics and Theoretical Physics, Queen' s University, Belfast BT7 INN (United Kingdom); Assafrao, D; Mohallem, J R [Laboratorio de Atomos e Moleculas Especiais, Departamento de Fisica, ICEx, Universidade Federal de Minas Gerais, P.O Box 702, 30123-970 Belo Horizonte, MG (Brazil); Whelan, Colm T, E-mail: mmcgovern06@qub.ac.u [Department of Physics, Old Dominion University, Norfolk, VA 23529-0116 (United States)

    2009-11-01

    We shall present results for antiproton ionization of H and He ranging from fully differential cross sections to total ionization. The calculations have been made in a coupled pseudostate impact parameter approximation. It will be shown that the interaction between the antiproton and the target nucleus is very important at low energies.

  15. Antiproton-nucleus experiments at LEAR and KAON

    International Nuclear Information System (INIS)

    Yavin, A.I.

    1989-12-01

    Antimatter and matter-antimatter systems are briefly discussed. Results of the antiproton-nucleus scattering experiments at LEAR are described, with the emphasis on unfinished experiments and on proposed experiments yet untouched. A few remarks on antiproton and antideuteron experiments at KAON are then presented

  16. Experiment to measure the gravitational force on the antiproton

    International Nuclear Information System (INIS)

    Brown, R.E.

    1985-01-01

    A collaboration has been formed to measure the acceleration of antiprotons in the earth's gravitational field. The technique is to produce, decelerate, and trap quantities of antiprotons, to cool them to untralow energy, and to measure their acceleration in a time-of-flight experiment. Present plans and the results of initial efforts toward this end are presented

  17. Low-energy antiprotons physics and the FLAIR facility

    International Nuclear Information System (INIS)

    Widmann, E

    2015-01-01

    FLAIR, the Facility for low-energy antiproton and ion research has been proposed in 2004 as an extension of the planned FAIR facility at Darmstadt, Germany. FLAIR was not included into the modularized start version of FAIR, but the recent installation of the CRYRING storage ring at GSI Darmstadt has opened new perspectives for physics with low-energy antiprotons at FAIR. (paper)

  18. Antiproton acceleration in the Fermilab Main Ring and Tevatron

    International Nuclear Information System (INIS)

    Martin, P.; Dinkel, J.; Ducar, R.

    1987-01-01

    The operation of the Fermilab Main Ring and Tevatron rf systems for colliding beams physics is discussed. The changes in the rf feedback system required for acceleration of antiprotons, and the methods for achieving proper transfer of both protons and antiprotons are described. Data on acceleration and transfer efficiencies are presented

  19. Measurement of strong interaction effects in antiprotonic helium atoms

    International Nuclear Information System (INIS)

    Davies, J.D.; Gorringe, T.P.; Lowe, J.; Nelson, J.M.; Playfer, S.M.; Pyle, G.J.; Squier, G.T.A.

    1984-01-01

    The strong interaction shift and width for the 2 p level and the width for the 3d level have been measured for antiprotonic helium atoms. The results are compared with optical model calculations. The possible existence of strongly bound antiproton states in nuclei is discussed. (orig.)

  20. Measurement of strong interaction parameters in antiprotonic hydrogen and deuterium

    CERN Document Server

    Augsburger, M A; Borchert, G L; Chatellard, D; Egger, J P; El-Khoury, P; Gorke, H; Gotta, D; Hauser, P R; Indelicato, P J; Kirch, K; Lenz, S; Siems, T; Simons, L M

    1999-01-01

    In the PS207 experiment at CERN, X-rays from antiprotonic hydrogen and deuterium have been measured at low pressure. The strong interaction shift and the broadening of the K/sub alpha / transition in antiprotonic hydrogen were $9 determined. Evidence was found for the individual hyperfine components of the protonium ground state. (7 refs).

  1. Intensity-Frontier Antiproton Physics with The Antiproton Annihilation Spectrometer (TAPAS) at Fermilab

    Energy Technology Data Exchange (ETDEWEB)

    Apollinari, Giorgio; /Fermilab; Asner, David M.; /PNL, Richland; Baldini, Wander; /INFN, Ferrara; Bartoszek, Larry; Broemmelsiek, Daniel R.; Brown, Charles N.; /Fermilab; Chakravorty, Alak; /St. Xavier U., Chicago; Colas, Paul; /Saclay; Derwent, Paul; /Fermilab; Drutskoy, Alexey; /Moscow, ITEP; Fortner, Michael; /Northern Illinois U. /Saclay /Indian Inst. Tech., Hyderabad

    2011-11-01

    The Fermilab Antiproton Source is the world's most intense source of antimatter. With the Tevatron program now behind us, this unique facility can help make the case for Fermilab's continued accelerator operations. The Antiproton Source can be used for unique, dedicated antimatter studies, including medium-energy {bar p}-annihilation experiments. We propose to assemble a powerful, yet cost-effective, solenoidal magnetic spectrometer for antiproton-annihilation events, and to use it at the Fermilab Antiproton Accumulator to measure the charm production cross section, study rare hyperon decays, search for hyperon CP asymmetry, precisely measure the properties of several charmonium and nearby states, and make the first measurements of the Drell-Yan continuum in medium-energy antiproton annihilation. Should the charm production cross section be as large as some have proposed, we will also be able to measure D{sup 0}-{bar D}{sup 0} mixing with high precision and discover (or sensitively limit) charm CP violation. The observation of charm or hyperon CP violation would be evidence for physics beyond the Standard Model, with possible implications for the origin of the baryon asymmetry of the universe - the question of what happened to all the antimatter that must have been produced in the Big Bang. The experiment will be carried out by an international collaboration and will require some four years of running time. As possibly the sole hadron experiment in progress at Fermilab during that time, it will play an important role in maintaining a broad particle physics program at Fermilab and in the U.S. It will thus help us to continue attracting creative and capable young people into science and technology, and introducing them to the important technologies of accelerators, detectors, and data acquisition and analysis - key roles in society that accelerator-based particle physics has historically played.

  2. Studies of Lear antiproton deceleration: radiofrequency quadripole or synchrotron

    International Nuclear Information System (INIS)

    Iazzourene, F.

    1987-06-01

    The aim of this work is to study a radiofrequency quadrupole (RFQ) and a synchrotron as decelerating systems for antiprotons extracted from the Low Energy Antiproton Ring (LEAR) at CERN. Antiprotons at energies lower than those available from LEAR are need by some experiments, eg. the measurement of the mass difference between protons and antiprotons with 10 -9 accuracy, using a Smith and Princeton spectrometer, and the measurement of gravitation on the antiprotons, using a trap. Depending on the LEAR performances, one can conclude that the RFQ is suitable for the experiment on the gravitation, and the synchrotron, owing to its electron cooling system, is a better solution for the experiment on the mass difference measurement, because of the very small acceptance of the spectrometer [fr

  3. Fermilab Antiproton source, Recycler ring and Main Injector

    Energy Technology Data Exchange (ETDEWEB)

    Nagaitsev, Sergei [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

    2013-03-22

    The antiproton source for a proton-antiproton collider at Fermilab was proposed in 1976 [1]. The proposal argued that the requisite luminosity (~1029 cm-2sec-1) could be achieved with a facility that would produce and cool approximately 1011 antiprotons per day. Funding for the Tevatron I project (to construct the Antiproton source) was initiated in 1981 and the Tevatron ring itself was completed, as a fixed target accelerator, in the summer of 1983 and the Antiproton Source was completed in 1985. At the end of its operations in 2011, the Fermilab antiproton production complex consisted of a sophisticated target system, three 8-GeV storage rings (namely the Debuncher, Accumulator and Recycler), 25 independent multi-GHz stochastic cooling systems, the world’s only relativistic electron cooling system and a team of technical experts equal to none. Sustained accumulation of antiprotons was possible at the rate of greater than 2.5×1011 per hour. Record-size stacks of antiprotons in excess of 3×1012 were accumulated in the Accumulator ring and 6×1012 in the Recycler. In some special cases, the antiprotons were stored in rings for more than 50 days. Note, that over the years, some 1016 antiprotons were produced and accumulated at Fermilab, which is about 17 nanograms and more than 90% of the world’s total man-made quantity of nuclear antimatter. The accelerator complex at Fermilab supported a broad physics program including the Tevatron Collider Run II [2], neutrino experiments using 8 GeV and 120 GeV proton beams, as well as a test beam facility and other fixed target experiments using 120 GeV primary proton beams. The following sections provide a brief description of Fermilab accelerators as they operated at the end of the Collider Run II (2011).

  4. What can an antiproton and a nucleus learn from each other

    International Nuclear Information System (INIS)

    Garreta, D.

    1982-05-01

    Simple features which make a low-energy antiproton an interesting probe of the nucleus, and a nucleus an interesting target for an antiproton are presented. Then antiproton-nucleus inelastic and elastic scattering, proton knock-out reactions on nuclei, annihilation of the antiproton in nuclei are reviewed. The aims of the experiment PS184 at LEAR are given

  5. LEAP [Low-Energy Antiproton]: A balloon-borne search for low-energy cosmic-ray antiprotons

    International Nuclear Information System (INIS)

    Moats, A.R.M.

    1989-01-01

    The LEAP (Low-Energy Antiproton) experiment is a search for cosmic-ray antiprotons in the 120 MeV to 1.2 GeV kinetic energy range. The motivation for this project was the result announced by Buffington et. al. (1981) that indicated an anomalously high antiproton flux below 300 MeV; this result has compelled theorists to propose sources of primary antiprotons above the small secondary antiproton flux produced by high energy cosmic-ray collisions with nuclei in the interstellar medium. LEAP consisted of the NMSU magnetic spectrometer, a time-of-flight system designed at Goddard Space Flight Center, two scintillation detectors, and a Cherenkov counter designed and built at the University of Arizona. Analysis of flight data performed by the high-energy astrophysics group at Goddard Space Flight Center revealed no antiproton candidates found in the 120 MeV to 360 MeV range; 3 possible antiproton candidate events were found in the 500 MeV to 1.2 GeV range in an analysis done here at the University of Arizona. However, since it will be necessary to sharpen the calibration on all of the LEAP systems in order to positively identify these events as antiprotons, only an upper limit has been determined at present. Thus, combining the analyses performed at the University of Arizona and Goddard Space Flight Center, 90% confidence upper limits of 3.5 x 10 -5 in the 120 MeV to 360 MeV range and 2.3 x 10 -4 in the 500 MeV to 1.2 GeV range for the antiproton/proton ratio is indicated by the LEAP results. LEAP disagrees sharply with the results of the Buffington group, indicating a low antiproton flux at these energies

  6. Stochastic Cooling at the CERN Antiproton Decelerator

    CERN Document Server

    Carli, Christian

    2000-01-01

    When transforming the CERN Antiproton Collector (AC) into the Antiproton Decelerator (AD), the stochastic cooling systems were rebuilt to cope with the new requirements. Instead of using the original three frequency bands, (0.9-1.6 GHz, 1.6-2.45 GHz and 2.4-3.2 GHz) only the first of these was used due to lattice limitations and other constraints. The same pick-ups and kickers are in use at two different energies. As in the AC, simultaneous cooling in all three phase planes is required. Switching between two transmission paths (at 3.5 GeV/c and 2.0 GeV/c) became necessary, including separate notch filters and delay compensation for the kicker sections. The tanks has to be rendered bakeable (150 C) to make the vacuum properties (<10-10 Torr) compatible with deceleration to low energies. Further improvements included programmable, phase-invariant electronic attenuators and amplitude-invariant delays. Experience during commissioning showed that careful optimization (depth and periodicity) of the notch filters...

  7. Laser Spectroscopy of Antiprotonic Helium Atoms

    CERN Multimedia

    2002-01-01

    %PS205 %title\\\\ \\\\Following the discovery of metastable antiprotonic helium atoms ($\\overline{p}He^{+} $) at KEK in 1991, systematic studies of their properties were made at LEAR from 1991 to 1996. In the first two years the lifetime of $\\overline{p}He^{+}$ in liquid and gaseous helium at various temperatures and pressures was measured and the effect of foreign gases on the lifetime of these atoms was investigated. Effects were also discovered which gave the antiproton a 14\\% longer lifetime in $^4$He than in $^3$He, and resulted in important differences in the shape of the annihilation time spectra in the two isotopes.\\\\ \\\\Since 1993 laser spectroscopy of the metastable $\\overline{p}He^{+}$ atoms became the main focus of PS205. Transitions were stimulated between metastable and non-metastable states of the $\\overline{p}He^{+}$ atom by firing a pulsed dye laser beam into the helium target every time an identified metastable atom was present (Figure 1). If the laser frequency matched the transition energy, the...

  8. The antiproton ion collider at FAIR

    International Nuclear Information System (INIS)

    Fabbietti, L.; Faestermann, T.; Homolka, J.; Kienle, P.; Kruecken, R.; Ring, P.; Suziki, K.; Beller, P.; Bosch, F.; Frankze, B.; Kozhuharov, C.; Nolden, F.; Cargnelli, M.; Fuhrmann, H.; Hirtl, A.; Marton, J.; Widmann, E.; Zmeskal, J.; Hayano, R.S.; Yamaguchi, T.; Lenske, H.; Litvinov, Y.; Shatunov, Y.; Skrinsky, A.N.; Vostrikov, V.A.; Wycech, S.

    2005-01-01

    A novel method is proposed to determine the charge and the matter radii instable and short lived nuclei using an pBar-A collider. The experiment makes use of the appropriately modified electron-ion collider Elise, to collide 30 MeV anti-protons with 740 AMeV ions. The anti-protons are first collected in the CR ring with 3 GeV energy and then cooled in the RESR ring to 30 MeV. The heavy ions produced in the SFRS are precooled in the CR ring, cooled in the RESR ring to 740 AMeV and fed to the NESR ring. The total pBar-nucleon annihilation cross-section is measured detecting the loss of stored ions and the pBar-n, pBar-p cross-sections detecting the A - 1 (Z - 1 or N - 1) nuclei left over after the annihilation, using the Schottcky method. Theoretical predictions show that the annihilation cross-section is proportional to the mean squared radius. (author)

  9. Analysis of the impact of chest wall constraints on eligibility for a randomized trial of stereotactic body radiotherapy of peripheral stage 1 non-small cell lung cancer

    International Nuclear Information System (INIS)

    Siva, Shankar; Shaw, Mark; Gill, Suki; David, Ball; Chesson, Brent

    2012-01-01

    Chest wall toxicities are recognized complications of stereotactic radiotherapy (SBRT) in non-small cell lung cancer. To minimize toxicity, the Trans-Tasman Radiation Oncology Group (TROG) 09.02 ‘CHISEL’ study protocol excluded patients with tumours within 1cm of the chest wall. The purpose of this study is to evaluate the implication of chest wall proximity constraints on patient eligibility, toxicity and potential accrual. Exclusion zones of 1cm beyond the mediastinum and 2cm beyond the bifurcation of the lobar bronchi were incorporated into the CHISEL credentialing CT dataset. Volumes of lung within which tumours varying from 1cm to 5cm in diameter may occupy and remain eligible for the CHISEL study were calculated. These volumes were compared to a hypothetical model in which the 1cm chest wall proximity restriction was removed. The percentage of lung area in which a tumour mass can occupy and be suitable for CHISEL in the left and right lung were 54% and 60% respectively. Removing the constraint increased the percentage of available lung to 83% and 87% respectively. Considering a 2cm spherical tumour, only 21% and 31% of tumours in the left and right lung would be eligible with the chest wall constraint, whilst 39% and 50% respectively would be eligible without the constraint. The exclusion of tumours less than 1cm to chest wall significantly reduces the proportion of patients eligible for the CHISEL protocol. A review of the literature pertaining to chest wall toxicity after stereotactic radiotherapy supports a change in chest wall exclusion criteria for the CHISEL study.

  10. Atomic physics of the antimatter explored with slow antiprotons

    International Nuclear Information System (INIS)

    Torii, Hiroyuki A.

    2010-01-01

    Frontiers of antimatter physics are reviewed, with a focus on our ASACUSA collaboration, doing research on 'Atomic Spectroscopy And Collisions Using Slow Antiprotons' at the 'Antiproton Decelerator' facility at CERN. Antiprotonic helium atoms give a unique test ground for testing CPT invariance between particles and antiparticles. Laser spectroscopy of this exotic atom has reached a precision of a few parts per billion in determation of the antiproton mass. We also have developed techniques to decelerate antiprotons and cool them to sub-eV energies in an electromagnetic trap at ultra-high vacuum and extract them as an ultra-slow beam at typically 250 eV. This unique low-energy beam opens up the possibility to study ionization and formation of antiprotonic atoms. The antihydrogen has been synthesized at low temperature in nested Penning traps by ATRAP and ATHENA(presently ALPHA) collaborations. Confinement of this neutral anti-atoms in a trap with magnetic field gradient is being studied, with an aim of 1S-2S laser spectroscopy in the future. ASACUSA has prepared a cusp trap for production of antihydrogen atoms, and aims at microwave spectroscopy between the hyperfine states of spin-polarized antihydrogen. A wide variety of low-energy antiproton physics also includes measurement of nuclear scattering, radiational biological effects, and gravity test of antimatter. (author)

  11. Muon, positron and antiproton interactions with atoms and molecules

    Energy Technology Data Exchange (ETDEWEB)

    Armour, Edward A G, E-mail: edward.armour@nottingham.ac.u [School of Mathematical Sciences, University of Nottingham, Nottingham NG7 2RD (United Kingdom)

    2010-04-01

    In this paper, a description is given of some interesting processes involving the interaction of a muon, a positron, or an antiproton with atoms and molecules. The process involving a muon is the resonant formation of the muonic molecular ion, dt{mu}, in the muon catalyzed fusion cycle. In the case of a positron, the process considered is positron annihilation in low-energy positron scattering by the hydrogen molecule. The antiproton is considered as the nucleus of an antihydrogen atom interacting with simple atoms. Attention is given to antiproton annihilation through the strong interaction. An outline is given of proposed tests of fundamental physics to be carried out using antihydrogen.

  12. Prospects for antiproton physics, my perspective

    International Nuclear Information System (INIS)

    Oelert, Walter

    2012-01-01

    These closing remarks are not supposed to be a summary talk, for this please have a look to the individual contributions to be published in the proceedings, but rather some considerations on future prospects for antiproton physics. However, first I would like to appreciate the organizers idea for giving me the opportunity to thank them for a well balanced, exciting and interesting conference LEAP-2011 in this marvelous city of Vancouver. I am sure we all loved to be here and enjoyed the hospitality and the bond of friendship we could experience during these days. We appreciate the patience and help of all the local organizers where I especially would like to mention Jana Thomson for her endless and helpful assignment. Thank you all—the participants, the speakers, the conference chair, the sponsors—for making this conference a success and we are looking forward to the next occasion in this series of meetings which will be celebrated in Uppsala.

  13. Prospects for antiproton physics, my perspective

    Energy Technology Data Exchange (ETDEWEB)

    Oelert, Walter, E-mail: w.oelert@fz-juelich.de [Forschungszentrum Juelich (Germany)

    2012-12-15

    These closing remarks are not supposed to be a summary talk, for this please have a look to the individual contributions to be published in the proceedings, but rather some considerations on future prospects for antiproton physics. However, first I would like to appreciate the organizers idea for giving me the opportunity to thank them for a well balanced, exciting and interesting conference LEAP-2011 in this marvelous city of Vancouver. I am sure we all loved to be here and enjoyed the hospitality and the bond of friendship we could experience during these days. We appreciate the patience and help of all the local organizers where I especially would like to mention Jana Thomson for her endless and helpful assignment. Thank you all-the participants, the speakers, the conference chair, the sponsors-for making this conference a success and we are looking forward to the next occasion in this series of meetings which will be celebrated in Uppsala.

  14. Antiproton-nucleon physics at LEAR

    International Nuclear Information System (INIS)

    Duclos, J.

    1985-02-01

    Antiproton beams from LEAR have been supplied in 1984 to 16 experiments about 10 12 particules at 200, 300, 600 and 1500 MeV/c have been delivered during 60 days of machine time. In nuclear physics, anti p-nuclei scattering and atomic X rays have been measured. In hydrogen, atomic L and K transitions have been detected. Searches have been made for baryonia with rather negative results. The p anti p annihilation at rest in various meson channels, selecting the initial anti p-wave, has been observed. The annihilation in electron-positron pair at rest and in flight has been measured and a value of the proton form factor is derived [fr

  15. The CERN SPS proton–antiproton collider

    CERN Document Server

    Schmidt, Rudiger

    2016-01-01

    One of CERN's most ambitious and successful projects was the search for the intermediate bosons, W and Z [1]. The accelerator part of the project relied on a number of innovations in accelerator physics and technology. The invention of the method of stochastic cooling and the extension by many orders of magnitude beyond the initial proof of principle demonstration allowed the construction of the Antiproton Accumulator. Major modifications to the 26 GeV PS complex and the conversion of the 300 GeV SPS, which had just started up as an accelerator, to a collider were required. The SPS collider had to master the beam–beam effect far beyond limits reached before and had to function in a tight symbiosis with the UA1 and UA2 experiments.

  16. Measurement of antiproton production in $p$–He collisions at LHCb to constrain the secondary cosmic antiproton flux

    CERN Document Server

    Graziani, Giacomo

    2018-01-01

    The flux of cosmic ray antiprotons is a powerful tool for indirect detection of dark matter. The sensitivity is limited by the uncertainty on the predicted antiproton flux from scattering of primary rays on the interstellar medium. This is, in turn, limited by the knowledge of production cross-sections, notably in p–He scattering. Thanks to its internal gas target, the LHCb experiment performed the first measurement of antiproton production from collisions of LHC proton beams on He nuclei at rest. The results and prospects are presented.

  17. Do positrons and antiprotons respect the weak equivalence principle?

    International Nuclear Information System (INIS)

    Hughes, R.J.

    1990-01-01

    We resolve the difficulties which Morrison identified with energy conservation and the gravitational red-shift when particles of antimatter, such as the positron and antiproton, do not respect the weak equivalence principle. 13 refs

  18. Antiproton cell experiment: antimatter is a better killer

    CERN Multimedia

    2006-01-01

    "European Organization for Nuclear Research is reporting that results from a three year study of antiprotons for neoplasm irrdiation showed a better cellular killer with a smaller lethal dose." (1,5 page)

  19. New results on strong-interaction effects in antiprotonic hydrogen

    CERN Document Server

    Gotta, D; Augsburger, M A; Borchert, G L; Castelli, C M; Chatellard, D; El-Khoury, P; Egger, J P; Gorke, H; Hauser, P R; Indelicato, P J; Kirch, K; Lenz, S; Nelms, N; Rashid, K; Schult, O W B; Siems, T; Simons, L M

    1999-01-01

    Lyman and Balmer transitions of antiprotonic hydrogen and deuterium have been measured at the low-energy antiproton ring LEAR at CERN in order to determine the strong interaction effects. The X-rays were detected using charge-coupled devices (CCDs) and a reflection type crystal spectrometer. The results of the measurements support the meson-exchange models describing the medium and long range part of the nucleon-antinucleon interaction. (33 refs).

  20. New results on strong-interaction effects in antiprotonic hydrogen

    International Nuclear Information System (INIS)

    Anagnostopoulos, D. F.; Augsburger, M.; Borchert, G.; Castelli, C.; Chatellard, D.; El-Khoury, P.; Egger, J.-P.; Gorke, H.; Gotta, D.; Hauser, P.; Indelicato, P.; Kirch, K.; Lenz, S.; Nelms, N.; Rashid, K.; Schult, O. W. B.; Siems, Th.; Simons, L. M.

    1999-01-01

    Lyman and Balmer transitions of antiprotonic hydrogen and deuterium have been measured at the Low-Energy Antiproton Ring LEAR at CERN in order to determine the strong interaction effects. The X-rays were detected using Charge-Coupled Devices (CCDs) and a reflection type crystal spectrometer. The results of the measurements support the meson-exchange models describing the medium and long range part of the nucleon-antinucleon interaction

  1. A measurement of the gravitational acceleration of the antiproton

    International Nuclear Information System (INIS)

    Holzscheiter, M.H.

    1990-01-01

    A fundamental experiment in gravity proposed by us, is the measurement of the gravitational force on antimatter. This measurement would constitute the first direct test of the Weak Equivalence Principle (WEP) for antimatter. The availability of low-energy antiprotons at CERN has made such an experiment feasible, and a proposal to carry out such a measurement has been accepted by the CERN Program Committee. We plan to use a time-of-flight technique similar to that pioneered by Fairbank and Witteborn in their measurement of the gravitational force on an electron. Very slow particles are launched into a vertical drift tube and the time-of-flight spectrum of these particles is recorded. This spectrum will exhibit a cut-off point directly related to the gravitational acceleration of the particles. Obtaining very slow antiprotons involves several stages of deceleration. Antiprotons from LEAR will be initially decelerated from 2 MeV to tens of kilovolts by passing them through a thin foil. After capture and cooling in a series of ion traps, the antiprotons will be in a thermal distribution with a temperature of a few degrees Kelvin. These ultra-cold antiprotons will then be released a few at a time into the drift tube. A detector will measure the arrival time of the particles at the exit of the drift tube. H - -ion, which have almost identical electromagnetic properties to the antiprotons, will be used for comparison and as a calibration standard. 7 refs., 1 fig

  2. Study of hyperon-antihyperon production in antiproton-proton collision at 4 GeV/c; Etude de la production d'hyperon et d'antihyperon dans les collisions antiproton-proton a 4 GeV/c

    Energy Technology Data Exchange (ETDEWEB)

    Revel, D [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1965-05-15

    We present the results on hyperon-antihyperon production by 4 GeV/c antiprotons in hydrogen. We used about 10{sup 5} pictures taken in an antiproton beam from the CERN proton synchrotron with the 81 cm Saclay hydrogen bubble chamber. The aim of this work was the study, through the cross sections and the angular distributions, of production mechanism of hyperon antihyperon pairs and excited hyperons (or antihyperons). For most of the channels, these angular distributions show a strong forward peaking of the antihyperon in the center of mass of the interaction. This suggests that a peripheral-type mechanism is predominant in these processes. We compare the results of some cross sections, with theoretical predictions according to SU{sub 3} unitary symmetry. (author) [French] Nous presentons ici des resultats concernant la production d'hyperons et d'antihyperons dans l'interaction antiproton sur proton a 4 GeV/c. Nous avons utilise pour cette experience un lot de 10{sup 5} photographies, prises avec la chambre a bulles de 81 cm a hydrogene liquide de Saclay, placee dans un faisceau d'antiprotons aupres du synchrotron a protons du CERN. Le but de ce travail etait l'etude des mecanismes de production des paires hyperons antihyperons et des hyperons excites (antihyperons excites) au travers des sections efficaces et des distributions angulaires. Pour la plupart des voies, ces distributions angulaires, dans le systeme du centre de masse, indiquent une forte tendance a l'emission vers l'avant de l'antihyperon, ce qui suggere un mecanisme de production de type peripherique. Nous avons compare les resultats de certaines sections efficaces avec des previsions obtenues a partir de la theorie de symetrie unitaire SU{sub 3}. (auteur)

  3. Radiation-induced rib fracture after stereotactic body radiotherapy with a total dose of 54-56 Gy given in 9-7 fractions for patients with peripheral lung tumor: impact of maximum dose and fraction size.

    Science.gov (United States)

    Aoki, Masahiko; Sato, Mariko; Hirose, Katsumi; Akimoto, Hiroyoshi; Kawaguchi, Hideo; Hatayama, Yoshiomi; Ono, Shuichi; Takai, Yoshihiro

    2015-04-22

    Radiation-induced rib fracture after stereotactic body radiotherapy (SBRT) for lung cancer has been recently reported. However, incidence of radiation-induced rib fracture after SBRT using moderate fraction sizes with a long-term follow-up time are not clarified. We examined incidence and risk factors of radiation-induced rib fracture after SBRT using moderate fraction sizes for the patients with peripherally located lung tumor. During 2003-2008, 41 patients with 42 lung tumors were treated with SBRT to 54-56 Gy in 9-7 fractions. The endpoint in the study was radiation-induced rib fracture detected by CT scan after the treatment. All ribs where the irradiated doses were more than 80% of prescribed dose were selected and contoured to build the dose-volume histograms (DVHs). Comparisons of the several factors obtained from the DVHs and the probabilities of rib fracture calculated by Kaplan-Meier method were performed in the study. Median follow-up time was 68 months. Among 75 contoured ribs, 23 rib fractures were observed in 34% of the patients during 16-48 months after SBRT, however, no patients complained of chest wall pain. The 4-year probabilities of rib fracture for maximum dose of ribs (Dmax) more than and less than 54 Gy were 47.7% and 12.9% (p = 0.0184), and for fraction size of 6, 7 and 8 Gy were 19.5%, 31.2% and 55.7% (p = 0.0458), respectively. Other factors, such as D2cc, mean dose of ribs, V10-55, age, sex, and planning target volume were not significantly different. The doses and fractionations used in this study resulted in no clinically significant rib fractures for this population, but that higher Dmax and dose per fraction treatments resulted in an increase in asymptomatic grade 1 rib fractures.

  4. Radiation-induced rib fracture after stereotactic body radiotherapy with a total dose of 54–56 Gy given in 9–7 fractions for patients with peripheral lung tumor: impact of maximum dose and fraction size

    International Nuclear Information System (INIS)

    Aoki, Masahiko; Sato, Mariko; Hirose, Katsumi; Akimoto, Hiroyoshi; Kawaguchi, Hideo; Hatayama, Yoshiomi; Ono, Shuichi; Takai, Yoshihiro

    2015-01-01

    Radiation-induced rib fracture after stereotactic body radiotherapy (SBRT) for lung cancer has been recently reported. However, incidence of radiation-induced rib fracture after SBRT using moderate fraction sizes with a long-term follow-up time are not clarified. We examined incidence and risk factors of radiation-induced rib fracture after SBRT using moderate fraction sizes for the patients with peripherally located lung tumor. During 2003–2008, 41 patients with 42 lung tumors were treated with SBRT to 54–56 Gy in 9–7 fractions. The endpoint in the study was radiation-induced rib fracture detected by CT scan after the treatment. All ribs where the irradiated doses were more than 80% of prescribed dose were selected and contoured to build the dose-volume histograms (DVHs). Comparisons of the several factors obtained from the DVHs and the probabilities of rib fracture calculated by Kaplan-Meier method were performed in the study. Median follow-up time was 68 months. Among 75 contoured ribs, 23 rib fractures were observed in 34% of the patients during 16–48 months after SBRT, however, no patients complained of chest wall pain. The 4-year probabilities of rib fracture for maximum dose of ribs (Dmax) more than and less than 54 Gy were 47.7% and 12.9% (p = 0.0184), and for fraction size of 6, 7 and 8 Gy were 19.5%, 31.2% and 55.7% (p = 0.0458), respectively. Other factors, such as D2cc, mean dose of ribs, V10–55, age, sex, and planning target volume were not significantly different. The doses and fractionations used in this study resulted in no clinically significant rib fractures for this population, but that higher Dmax and dose per fraction treatments resulted in an increase in asymptomatic grade 1 rib fractures

  5. Radiotherapy physics

    International Nuclear Information System (INIS)

    Chen, G.T.Y.; Collier, J.M.; Lyman, J.T.; Pitluck, S.

    1982-01-01

    The Radiotherapy Physics Group works on the physical and biophysical aspects of charged particle radiotherapy. Our activities include the development of isosurvival beams (beams of uniform biological effect), computerized treatment planning development for charged particle radiotherapy, design of compensation to shape dose distributions, and development of dosimetry techniques to verify planned irradiations in both phantoms and patients

  6. The Floor's the Limit (Antiproton energies to hit new low)

    CERN Multimedia

    2000-01-01

    Celebrating the success of the RFQ in Aarhus. Left to right: Alessanda Lombardi (CERN), Iouri Bylinskii (CERN), Alex Csete (Aarhus), Ulrik Uggerhøj (Aarhus), Ryu Hayano (Tokyo, spokesman ASACUSA), Helge Knudsen (Aarhus), Werner Pirkl (CERN), Ryan Thompson (Aarhus), Søren P. Møller (Aarhus). Although in particle physics we are accustomed to strive for higher and higher energies, this is not always the most interesting thing to do with antiprotons. Indeed, as recent issues of the Bulletin have suggested, the signpost on the road to a closer look at the antiproton points towards ever-lower energies. The CERN Antiproton Decelerator decelerates antipro-tons emerging from a target placed in the path of a 26 GeV/c proton beam from 90 % of to about 10 % of the speed of light. However, even this is far too fast for many of the most interesting experiments on antiprotons planned by Danish and Japanese members of the ASACUSA collaboration. Tokyo University has therefore financed the con...

  7. Large amounts of antiproton production by heavy ion collision

    International Nuclear Information System (INIS)

    Takahashi, Hiroshi; Powell, J.

    1987-01-01

    To produce large amounts of antiprotons, on the order of several grams/year, use of machines to produce nuclear collisions are studied. These can be of either proton-proton, proton-nucleus and nucleus-nucleus in nature. To achieve high luminosity colliding beams, on the order of 10 41 m/cm 2 , a self-colliding machine is required, rather than a conventional circular colliding type. The self-colliding machine can produce additional antiprotons through successive collisions of secondary particles, such as spectator nucleons. A key problem is how to collect the produced antiprotons without capture by beam nuclei in the collision zone. Production costs for anti-matter are projected for various energy source options and technology levels. Dedicated facilities using heavy ion collisions could produce antiproton at substantially less than 1 million $/milligram. With co-production of other valuable products, e.g., nuclear fuel for power reactors, antiproton costs could be reduced to even lower values

  8. A low-energy antiproton detector prototype for AFIS

    Energy Technology Data Exchange (ETDEWEB)

    Meng, Lingxin; Greenwald, Daniel; Hahn, Alexander; Hauptmann, Philipp; Konorov, Igor; Losekamm, Martin; Paul, Stephan; Poeschl, Thomas; Renker, Dieter [Technische Universitaet Muenchen (Germany)

    2014-07-01

    Antiprotons are produced in interactions of primary cosmic rays with earth's exosphere, where a fraction of them will be confined in the geomagnetic field in the inner van Allen Belt. The antiproton-to-proton flux ratio predicted by theory is in good agreement with recent results from the South Atlantic Anomaly (SAA) published by the PAMELA collaboration. We have designed the AFIS (Antiproton Flux in Space) project in order to extend the measurable range of antiprotons towards the low-energy region. In scope of this project a small antiproton detector consisting of scintillating fibers and silicon photomultipliers is being developed as payload for a CubeSat traversing the SAA in Low Earth Orbit. For the proof of concept we have built a prototype called ''CubeZero'' which completed its first test using pion and proton beams at PSI, Switzerland. Our primary goal was to investigate on the performance of tracking and Bragg peak identification in hardware and software. Analysis of detector performance based on data taken during this beam test is presented in this talk.

  9. Antiproton tagging and vertex fitting in a Timepix3 detector

    CERN Document Server

    Aghion, S.; The AEGIS collaboration; Antonello, M.; Belov, A.; Bonomi, G.; Brusah, R. S.; Caccia, M.; Camper, A.; Caravita, R.; Castelli, F.; Cerchiari, G.; Comparat, D.; Consolati, G.; Demetrio, A.; Di Noto, L.; Doser, M.; Evans, C.; Fanì, M.; Ferragut, R.; Fesel, J.; Fontana, A.; Gerber, S.; Giammarchi, M.; Gligorova, A.; Guatieri, F.; Hackstock, P.; Haider, S.; Hinterberger, A.; Holmestad, H.; Kellerbauer, A.; Khalidova, O.; Krasnický, D.; Lagomarsino, V.; Lansonneur, P.; Lebrun, P.; Malbrunot, C.; Mariazzi, S.; Marton, J.; Matveev, V.; Müller, S. R.; Nebbia, G.; Nedelec, P.; Oberthaler, M.; Pacifico, N.; Pagano, D.; Penasa, L.; Petracek, V.; Prelz, F.; Prevedelli, M.; Rienaecker, B.; Robert, J.; Røhne, O. M.; Rotondi, A.; Sandaker, H.; Santoro, R.; Smestad, L.; Sorrentino, F.; Testera, G.; Tietje, I. C.; Widmann, E.; Yzombard, P.; Zimmer, C.; Zmeskal, J.; Zurlo, N.

    2018-01-01

    Studies of antimatter are important for understanding our universe at a fundamental level. There are still unsolved problems, such as the matter-antimatter asymmetry in the universe. The AEgIS experiment at CERN aims at measuring the gravitational fall of antihydrogen in order to determine the gravitational force on antimatter. The proposed method will make use of a position-sensitive detector to measure the annihilation point of antihydrogen. Such a detector must be able to tag the antiproton, measure its time of arrival and reconstruct its annihilation point with high precision in the vertical direction. This work explores a new method for tagging antiprotons and reconstructing their annihilation point. Antiprotons from the Antiproton Decelerator at CERN was used to obtain data on direct annihilations on the surface of a silicon pixel sensor with Timepix3 readout. These data were used to develop and verify a detector response model for annihilation of antiprotons in this detector. Using this model and the a...

  10. Atomic Spectroscopy and Collisions Using Slow Antiprotons \\\\ ASACUSA Collaboration

    CERN Multimedia

    Matsuda, Y; Lodi-rizzini, E; Kuroda, N; Schettino, G; Hori, M; Pirkl, W; Mascagna, V; Leali, M; Malbrunot, C L S; Yamazaki, Y; Eades, J; Simon, M; Massiczek, O; Sauerzopf, C; Nagata, Y; Knudsen, H; Uggerhoj, U I; Mc cullough, R W; Toekesi, K M; Venturelli, L; Widmann, E; Zmeskal, J; Kanai, Y; Kristiansen, H; Todoroki, K; Bartel, M A; Moller, S P; Charlton, M; Diermaier, M; Kolbinger, B

    2002-01-01

    ASACUSA (\\underline{A}tomic \\underline{S}pectroscopy \\underline{A}nd \\underline{C}ollisions \\underline{U}sing \\underline{S}low \\underline{A}ntiprotons) is a collaboration between a number of Japanese and European research institutions, with the goal of studying bound and continuum states of antiprotons with simple atoms.\\\\ Three phases of experimentation are planned for ASACUSA. In the first phase, we use the direct $\\overline{p}$ beam from AD at 5.3 MeV and concentrate on the laser and microwave spectroscopy of the metastable antiprotonic helium atom, $\\overline{p}$He$^+$, consisting of an electron and antiproton bound by the Coulomb force to the helium nucleus. Samples of these are readily created by bringing AD antiproton beam bunches to rest in helium gas. With the help of techniques developed at LEAR for resonating high precision laser beams with antiproton transitions in these atoms, ASACUSA achieved several of these first-phase objectives during a few short months of AD operation in 2000. Six atomic tr...

  11. Large amounts of antiproton production by heavy ion collision

    Energy Technology Data Exchange (ETDEWEB)

    Takahashi, Hiroshi; Powell, J.

    1987-01-01

    To produce large amounts of antiprotons, on the order of several grams/year, use of machines to produce nuclear collisions are studied. These can be of either proton-proton, proton-nucleus and nucleus-nucleus in nature. To achieve high luminosity colliding beams, on the order of 10/sup 41/ m/cm/sup 2/, a self-colliding machine is required, rather than a conventional circular colliding type. The self-colliding machine can produce additional antiprotons through successive collisions of secondary particles, such as spectator nucleons. A key problem is how to collect the produced antiprotons without capture by beam nuclei in the collision zone. Production costs for anti-matter are projected for various energy source options and technology levels. Dedicated facilities using heavy ion collisions could produce antiproton at substantially less than 1 million $/milligram. With co-production of other valuable products, e.g., nuclear fuel for power reactors, antiproton costs could be reduced to even lower values.

  12. Spectroscopy of antiprotonic helium atoms and its contribution to the fundamental physical constants

    CERN Document Server

    Hayano, R S

    2010-01-01

    Antiprotonic helium atom, a metastable neutral system consisting of an antiproton, an electron and a helium nucleus, was serendipitously discovered, and has been studied at CERN’s antiproton decelerator facility. Its transition frequencies have recently been measured to nine digits of precision by laser spectroscopy. By comparing these experimental results with three-body QED calculations, the antiproton-to-electron massratio was determined as 1836.152674(5). This result contributed to the CODATA recommended values of the fundamental physical constants.

  13. Metastable states in antiprotonic helium atoms an island stability in a sea of continuum

    CERN Document Server

    Korobov, V I

    2002-01-01

    In this contribution we consider a phenomenon of metastable states in antiprotonic helium atoms, precise spectroscopy of these states and a present-day study of the electromagnetic properties of antiprotons. Calculation of nonrelativistic energies, relativistic and QED corrections as well as the fine and hyperfine structure and the magnetic moment of an antiproton are the main parts of this study. Refs. 22 (nevyjel)

  14. Energy and energy width measurement in the FNAL antiproton accumulator

    International Nuclear Information System (INIS)

    Church, M.; Hsueh, S.; Rapidis, P.; Werkema, S.

    1991-10-01

    The Fermilab Antiproton Accumulator has recently been used to produce Charmonium resonances (charm quark, anti-charm quark bound states) in proton-antiproton annihilations using an internal H 2 gas jet target. A measurement of the resonance mass and width may be obtained from a precise knowledge of the antiproton beam energy and energy spread. The beam energy is measured to an accuracy of 1 part in 10 4 in the range 6.3 Gev to 4.1 Gev by measuring the orbit length and revolution frequency of the beam. The beam momentum spread is measured to an accuracy of 10% by measuring the beam frequency spread and the parameter η = (P beam /F rev )·(dF rev /dP beam ). These two measurement techniques are described in this report

  15. Energy and energy width measurement in the FNAL antiproton accumulator

    Energy Technology Data Exchange (ETDEWEB)

    Church, M.; Hsueh, S.; Rapidis, P.; Werkema, S.

    1991-10-01

    The Fermilab Antiproton Accumulator has recently been used to produce Charmonium resonances (charm quark, anti-charm quark bound states) in proton-antiproton annihilations using an internal H{sub 2} gas jet target. A measurement of the resonance mass and width may be obtained from a precise knowledge of the antiproton beam energy and energy spread. The beam energy is measured to an accuracy of 1 part in 10{sup 4} in the range 6.3 Gev to 4.1 Gev by measuring the orbit length and revolution frequency of the beam. The beam momentum spread is measured to an accuracy of 10% by measuring the beam frequency spread and the parameter {eta} = (P{sub beam}/F{sub rev}){center_dot}(dF{sub rev}/dP{sub beam}). These two measurement techniques are described in this report.

  16. Improved Study of the Antiprotonic Helium Hyperfine Structure

    CERN Document Server

    Pask, T.; Dax, A.; Hayano, R.S.; Hori, M.; Horvath, D.; Juhasz, B.; Malbrunot, C.; Marton, J.; Ono, N.; Suzuki, K.; Zmeskal, J.; Widmann, E.

    2008-01-01

    We report the initial results from a systematic study of the hyperfine (HF) structure of antiprotonic helium (n,l) = (37,~35) carried out at the Antiproton Decelerator (AD) at CERN. We performed a laser-microwave-laser resonance spectroscopy using a continuous wave (cw) pulse-amplified laser system and microwave cavity to measure the HF transition frequencies. Improvements in the spectral linewidth and stability of our laser system have increased the precision of these measurements by a factor of five and reduced the line width by a factor of three compared to our previous results. A comparison of the experimentally measured transition frequencies with three body QED calculations can be used to determine the antiproton spin magnetic moment, leading towards a test of CPT invariance.

  17. Relativistic hydrodynamics, heavy ion reactions and antiproton annihilation

    International Nuclear Information System (INIS)

    Strottman, D.

    1985-01-01

    The application of relativistic hydrodynamics to relativistic heavy ions and antiproton annihilation is summarized. Conditions for validity of hydrodynamics are presented. Theoretical results for inclusive particle spectra, pion production and flow analysis are given for medium energy heavy ions. The two-fluid model is introduced and results presented for reactions from 800 MeV per nucleon to 15 GeV on 15 GeV per nucleon. Temperatures and densities attained in antiproton annihilation are given. Finally, signals which might indicate the presence of a quark-gluon plasma are briefly surveyed

  18. Antiproton-decelerating Radio-Frequency Quadrupole (RFQD), inner structure.

    CERN Multimedia

    Laurent Guiraud

    1999-01-01

    The inner structure of the RFQD, withdrawn from its tank. In picture _06, the upstream end is in the back and the view is on the downstream exit. The RFQD has a length of 3.5 m and operates at a frequency of 202.4 MHz. It further decelerates antiprotons from the Antiproton Decelerator (3.5 MeV/c to 100 MeV/c, or 5.3 MeV) to very low energies around 50 keV.

  19. Antiprotons from spallation of cosmic rays on ISM

    CERN Document Server

    Donato, F

    2002-01-01

    We provide the first evaluation of the secondary interstellar cosmic antiproton flux that is fully consistent with cosmic ray nuclei in the framework of a two-zone diffusion model. We also study and conservatively quantify all possible sources of uncertainty that may affect that antiproton flux. Uncertainties related to propagation are shown to range between 10% and 25%, depending on which part of the spectrum is considered, while the ones related to nuclear physics stand around 22-25 % over all the energy spectrum.

  20. 1-4 Strangeness Production in Antiproton Induced Nuclear Reactions.

    Institute of Scientific and Technical Information of China (English)

    Feng; Zhaoqing[1

    2014-01-01

    More localized energy deposition is able to be produced in antiproton-nucleus collisions in comparison withheavy-ion collisions due to annihilation reactions. Searching for the cold quark-gluon plasma (QGP) with antiprotonbeamshas been considered as a hot topic both in experiments and in theretical calculations over the past severaldecades. Strangeness production and hypernucleus formation in antiproton-induced nuclear reactions are importancein exploring the hyperon (antihyperon)-nucleon (HN) potential and the antinucleon-nucleon interaction, whichhave been hot topics in the forthcoming experiments at PANDA in Germany.

  1. Impact parameter analysis of proton-antiproton elastic scattering from √s=7.6 GeV to √s=546 GeV

    International Nuclear Information System (INIS)

    Fearnley, T.

    1985-09-01

    The proton-antiproton elastic profile function GAMMA (b) and inelastic overlap function Gsub(in)(b) are calculated from a coherent set of proton-antiproton elastic scattering data at Psub(L)=30 and 50 GeV/c (√s=7.6 and 9.8 GeV), and at √s=53 and 546 GeV. The energy dependence of Gsub(in)(b) is studied in the low energy regime and in the high energy regime. The increase of the inelastic cross section from 50 GeV/c to 30 GeV/c and from √s=53 GeV to √s=546 GeV is found to originate from a peripheral increase of Gsub(in) around 1 fm, accompanied by a non-negligible central increase. The proton-antiproton collision at √s=53 GeV is shown to be slightly less absorptive centrally than pp at this energy, while it is more absorptive peripherally around 1.2 fm. The inelastic overlap functions strongly disagree with the predictions of geometrical scaling and factorizing eikonal models, both in the low energy regime psub(L)=30-50 GeV/c and in the high energy regime √s=53-546 GeV

  2. Rapidity and centrality dependence of proton and anti-proton production from 197Au+197Au collisions at √(sNN) = 130 GeV

    International Nuclear Information System (INIS)

    Adams, J.; Adler, C.; Aggarwal, M.M.; Ahammed, Z.; Amonett, J.; Anderson, B.D.; Anderson, M.; Arkhipkin, D.; Averichev, G.S.; Badyal, S.K.; Balewski, J.; Barannikova, O.; Barnby, L.S.; Baudot, J.; Bekele, S.; Belaga, V.V.; Bellwied, R.; Berger, J.; Bezverkhny, B.I.; Bhardwaj, S.; Bhaskar, P.; Bhati, A.K.; Bichsel, H.; Billmeier, A.; Bland, L.C.; Blyth, C.O.; Bonner, B.E.; Botje, M.; Boucham, A.; Brandin, A.; Bravar, A.; Cadman, R.V.; Cai, X.Z.; Caines, H.; Calderon de la Barca Sanchez, M.; Cardenas, A.; Carroll, J.; Castillo, J.; Castro, M.; Cebra, D.; Chaloupka, P.; Chattopadhyay, S.; Chen, H.F.; Chen, Y.; Chernenko, S.P.; Cherney, M.; Chikanian, A.; Choi, B.; Christie, W.; Coffin, J.P.; Cormier, T.M.; Corral, M.M.; Cramer, J.G.; Crawford, H.J.; Das, D.; Das, S.; Derevschikov, A.A.; Didenko, L.; Dietel, T.; Dong, X.; Draper, J.E.; Du, F.; Dubey, A.K.; Dunin, V.B.; Dunlop, J.C.; Dutta Mazumdar, M.R.; Eckardt, V.; Efimov, L.G.; Emelianov, V.; Engelage, J.; Eppley, G.; Erazmus, B.; Fachini, P.; Faine, V.; Faivre, J.; Fatemi, R.; Filimonov, K.; Filip, P.; Finch, E.; Fisyak, Y.; Flierl, D.; Foley, K.J.; Fu, J.; Gagliardi, C.A.; Ganti, M.S.; Gutierrez, T.D.; Gagunashvili, N.; Gans, J.; Gaudichet, L.; Germain, M.; Geurts, F.; Ghazikhanian, V.; Ghosh, P.; Gonzalez, J.E.; Grachov, O.; Grigoriev, V.; Grosnick, D.; Guedon, M.; Guertin, S.M.; Gupta, A.; Gushin, E.; Hallman, T.J.; Hardtke, D.; Harris, J.W.; Heinz, M.; Henry, T.W.; Heppelmann, S.; Herston, T.; Hippolyte, B.; Hirsch, A.; Hjort, E.; Hoffmann, G.W.; Horsley, M.; Huang, H.Z.; Huang, S.L.; Humanic, T.J.; Igo, G.; Ishihara, A.; Jacobs, P.; Jacobs, W.W.; Janik, M.; Johnson, I.; Jones, P.G.; Judd, E.G.; Kabana, S.; Kaneta, M.; Kaplan, M.; Keane, D.; Kiryluk, J.; Kisiel, A.; Klay, J.; Klein, S.R.; Klyachko, A.; Koetke, D.D.; Kollegger, T.; Konstantinov, A.S.; Kopytine, M.; Kotchenda, L.; Kovalenko, A.D.; Kramer, M.; Kravtsov, P.; Krueger, K.; Kuhn, C.; Kulikov, A.I.; Kumar, A.

    2003-01-01

    We report on the rapidity and centrality dependence of proton and anti-proton transverse mass distributions from 197 Au + 197 Au collisions at √s NN = 130 GeV as measured by the STAR experiment at RHIC. Our results are from the rapidity and transverse momentum range of |y| t < 1.00 GeV/c. For both protons and anti-protons, transverse mass distributions become more convex from peripheral to central collisions demonstrating characteristics of collective expansion. The measured rapidity distributions and the mean transverse momenta versus rapidity are flat within |y| < 0.5. Comparisons of our data with results from model calculations indicate that in order to obtain a consistent picture of the proton(anti-proton) yields and transverse mass distributions the possibility of pre-hadronic collective expansion may have to be taken into account

  3. Peripheral reactions

    International Nuclear Information System (INIS)

    Greiner, D.

    1978-01-01

    Peripheral collisions, that is, collisions involving a small amount of overlap of nuclear matter, are discussed including inclusive interactions, the magnitude of the peripheral cross section, fragmentation, a compilation of experiments and available data, limiting fragmentation, factorization, some models, fragment momentum distributions, and future research directions

  4. Whither radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Ross, W M

    1987-03-01

    The 1986 Glyn Evans Memorial Lecture, given at the Joint Provincial Meeting of the Royal College of Radiologists, Sheffield, September 1986, sketches an outline of the history of radiotherapy and discusses the future development of the art. Topics included are siting of centres, training needs, the relationship of radiotherapy to other medical specialities, and the advantages and disadvantages of radiotherapy practitioners forming a separate medical College. (U.K.)

  5. Annihilation of antiprotons stopped in liquid hydrogen and deuterium

    International Nuclear Information System (INIS)

    Dalkarov, O.D.; Kerbikov, B.O.; Markushin, V.E.

    1976-01-01

    Detailed analysis is given of stopping antiproton annihilation in liquid hydrogen and deuterium. Connection between capture schedule and properties of bound states in nucleon-antinucleon system is established. The theoretical predictions are compared with experimental data which appeared in 1971-75

  6. Outer casing of the AA antiproton production target

    CERN Multimedia

    CERN PhotoLab

    1979-01-01

    The first version of the antiproton production target was a tungsten rod, 11 cm long (actually a row of 11 rods, each 1 cm long) and 3 mm in diameter. The rod was embedded in graphite, pressure-seated into an outer casing made of stainless steel. The casing had fins for forced-air cooling.

  7. Galactic diffusion and the antiproton signal of supersymmetric dark matter

    CERN Document Server

    Chardonnet, P; Salati, Pierre; Taillet, R

    1996-01-01

    The leaky box model is now ruled out by measurements of a cosmic ray gradient throughout the galactic disk. It needs to be replaced by a more refined treatment which takes into account the diffusion of cosmic rays in the magnetic fields of the Galaxy. We have estimated the flux of antiprotons on the Earth in the framework of a two-zone diffusion model. Those species are created by the spallation reactions of high-energy nuclei with the interstellar gas. Another potential source of antiprotons is the annihilation of supersymmetric particles in the dark halo that surrounds our Galaxy. In this letter, we investigate both processes. Special emphasis is given to the antiproton signature of supersymmetric dark matter. The corresponding signal exceeds the conventional spallation flux below 300 MeV, a domain that will be thoroughly explored by the Antimatter Spectrometer experiment. The propagation of the antiprotons produced in the remote regions of the halo back to the Earth plays a crucial role. Depending on the e...

  8. Enhancing trappable antiproton populations through deceleration and frictional cooling

    Energy Technology Data Exchange (ETDEWEB)

    Zolotorev, M.; Sessler, A.; Penn, G.; Wurtele, J. S.; Charman, A. E.

    2012-03-01

    CERN currently delivers antiprotons for trapping experiments with the Antiproton Decelerator (AD), which slows the antiprotons down to about 5 MeV.This energy is currently too high for direct trapping, and thick foils are used to slow down the beam to energies which can be trapped.To allow further deceleration to $\\sim 100 \\;\\mbox{keV}$, CERN is initiating the construction of ELENA,consisting of a ring which will combine RF deceleration and electron cooling capabilities. We describe a simple frictionalcooling scheme that can serve to provide significantly improved trapping efficiency, either directly from the AD or first usinga standard deceleration mechanism (induction linac or RFQ). This scheme could be implemented in a short time.The device itself is short in length, uses accessible voltages, and at reasonable cost could serve in the interim beforeELENA becomes operational, or possibly in lieu of ELENA for some experiments. Simple theory and simulations provide a preliminary assessment of theconcept and its strengths and limitations, and highlight important areas for experimental studies, in particular to pin down the level of multiplescattering for low-energy antiprotons. We show that the frictional cooling scheme can provide a similar energy spectrum to that of ELENA,but with higher transverse emittances.

  9. Hyperfine Structure Measurements of Antiprotonic $^3$He using Microwave Spectroscopy

    CERN Document Server

    Friedreich, Susanne

    The goal of this project was to measure the hyperfine structure of $\\overline{\\text{p}}^3$He$^+$ using the technique of laser-microwave-laser spectroscopy. Antiprotonic helium ($\\overline{\\text{p}}$He$^+$) is a neutral exotic atom, consisting of a helium nucleus, an electron and an antiproton. The interactions of the angular momenta of its constituents cause a hyperfine splitting ({HFS}) within the energy states of this new atom. The 3\\% of formed antiprotonic helium atoms which remain in a metastable, radiative decay-dominated state have a lifetime of about 1-3~$\\mu$s. This time window is used to do spectroscopic studies. The hyperfine structure of $\\overline{\\text{p}}^4$He$^+$ was already extensively investigated before. From these measurements the spin magnetic moment of the antiproton can be determined. A comparison of the result to the proton magnetic moment provides a test of {CPT} invariance. Due to its higher complexity the new exotic three-body system of $\\overline{\\text{p}}^3$He$^+$ is a cross-check...

  10. Calculated LET Spectrum from Antiproton Beams Stopping in Water

    DEFF Research Database (Denmark)

    Bassler, Niels; Holzscheiter, Michael

    2009-01-01

    significantly differ from unity, which seems to warrant closer inspection of the radiobiology in this region. Monte Carlo simulations using FLUKA were performed for calculating the entire particle spectrum of a beam of 126 MeV antiprotons hitting a water phantom. In the plateau region of the simulated...

  11. Constraints on particle dark matter from cosmic-ray antiprotons

    International Nuclear Information System (INIS)

    Fornengo, N.; Vittino, A.; Maccione, L.

    2014-01-01

    Cosmic-ray antiprotons represent an important channel for dark matter indirect-detection studies. Current measurements of the antiproton flux at the top of the atmosphere and theoretical determinations of the secondary antiproton production in the Galaxy are in good agreement, with no manifest deviation which could point to an exotic contribution in this channel. Therefore, antiprotons can be used as a powerful tool for constraining particle dark matter properties. By using the spectrum of PAMELA data from 50 MV to 180 GV in rigidity, we derive bounds on the dark matter annihilation cross section (or decay rate, for decaying dark matter) for the whole spectrum of dark matter annihilation (decay) channels and under different hypotheses of cosmic-rays transport in the Galaxy and in the heliosphere. For typical models of galactic propagation, the constraints are strong, setting a lower bound on the dark matter mass of a ''thermal'' relic at about 40–80 GeV for hadronic annihilation channels. These bounds are enhanced to about 150 GeV on the dark matter mass, when large cosmic-rays confinement volumes in the Galaxy are considered, and are reduced to 3–4 GeV for annihilation to light quarks (no bound for heavy-quark production) when the confinement volume is small. Bounds for dark matter lighter than few tens of GeV are due to the low energy part of the PAMELA spectrum, an energy region where solar modulation is relevant: to this aim, we have implemented a detailed solution of the transport equation in the heliosphere, which allowed us not only to extend bounds to light dark matter, but also to determine the uncertainty on the constraints arising from solar modulation modelling. Finally, we estimate the impact of soon-to-come AMS-02 data on the antiproton constraints

  12. Recommendations for implementing stereotactic radiotherapy in peripheral stage IA non-small cell lung cancer: report from the Quality Assurance Working Party of the randomised phase III ROSEL study

    International Nuclear Information System (INIS)

    Hurkmans, Coen W; Cuijpers, Johan P; Lagerwaard, Frank J; Widder, Joachim; Heide, Uulke A van der; Schuring, Danny; Senan, Suresh

    2009-01-01

    A phase III multi-centre randomised trial (ROSEL) has been initiated to establish the role of stereotactic radiotherapy in patients with operable stage IA lung cancer. Due to rapid changes in radiotherapy technology and evolving techniques for image-guided delivery, guidelines had to be developed in order to ensure uniformity in implementation of stereotactic radiotherapy in this multi-centre study. A Quality Assurance Working Party was formed by radiation oncologists and clinical physicists from both academic as well as non-academic hospitals that had already implemented stereotactic radiotherapy for lung cancer. A literature survey was conducted and consensus meetings were held in which both the knowledge from the literature and clinical experience were pooled. In addition, a planning study was performed in 26 stage I patients, of which 22 were stage 1A, in order to develop and evaluate the planning guidelines. Plans were optimised according to parameters adopted from RTOG trials using both an algorithm with a simple homogeneity correction (Type A) and a more advanced algorithm (Type B). Dose conformity requirements were then formulated based on these results. Based on current literature and expert experience, guidelines were formulated for this phase III study of stereotactic radiotherapy versus surgery. These guidelines can serve to facilitate the design of future multi-centre clinical trials of stereotactic radiotherapy in other patient groups and aid a more uniform implementation of this technique outside clinical trials

  13. Observation of Ultra-Slow Antiprotons using Micro-channel Plate

    Science.gov (United States)

    Imao, H.; Torii, H. A.; Nagata, Y.; Toyoda, H.; Shimoyama, T.; Enomoto, Y.; Higaki, H.; Kanai, Y.; Mohri, A.; Yamazaki, Y.

    2008-08-01

    Our group ASACUSA-MUSASHI has succeeded in accumulating several million antiprotons and extracting them as monochromatic ultra-slow antiproton beams (10 eV-1 keV) at CERN AD. We have observed ultra-slow antiprotons using micro-channel plates (MCP). The integrated pulse area of the output signals generated when the MCP was irradiated by ultra-slow antiprotons was 6 times higher than that by electrons. As a long-term effect, we also observed an increase in the background rate presumably due to the radioactivation of the MCP surface. Irradiating the antiproton beams on the MCP induces antiproton-nuclear annihilations only on the first layer of the surface. Low-energy and short-range secondary particles like charged nuclear fragments caused by the "surface nuclear reactions" would be the origin of our observed phenomena.

  14. Dark matter for excess of AMS-02 positrons and antiprotons

    Directory of Open Access Journals (Sweden)

    Chuan-Hung Chen

    2015-07-01

    Full Text Available We propose a dark matter explanation to simultaneously account for the excess of antiproton-to-proton and positron power spectra observed in the AMS-02 experiment while having the right dark matter relic abundance and satisfying the current direct search bounds. We extend the Higgs triplet model with a hidden gauge symmetry of SU(2X that is broken to Z3 by a quadruplet scalar field, rendering the associated gauge bosons stable weakly-interacting massive particle dark matter candidates. By coupling the complex Higgs triplet and the SU(2X quadruplet, the dark matter candidates can annihilate into triplet Higgs bosons each of which in turn decays into lepton or gauge boson final states. Such a mechanism gives rise to correct excess of positrons and antiprotons with an appropriate choice of the triplet vacuum expectation value. Besides, the model provides a link between neutrino mass and dark matter phenomenology.

  15. Pionic annihilation of antiprotons stopped on sup 3 He

    Energy Technology Data Exchange (ETDEWEB)

    Bendiscioli, G.; Filippini, V.; Rotondi, A.; Salvini, P.; Venaglioni, A. (Pavia Univ. (Italy). Dipt. di Fisica Nucleare e Teorica Istituto Nazionale di Fisica Nucleare, Pavia (Italy)); Bossolasco, S.; Bussa, M.P.; Busso, L.; Fava, L.; Ferrero, L.; Maggiora, A.; Panzieri, D.; Piragino, G.; Piragino, R.; Tosello, F. (Turin Univ. (Italy). Ist. di Fisica Generale Istituto Nazionale di Fisica Nucleare, Turin (Italy)); Batusov, Yu.A.; Falomkin, I.V.; Pontecorvo, G.B.; Rozhdestvensky, A.M.; Sapozhnikov, M.G.; Tretyak, V.I. (Joint Inst. for Nuclear Research, Dubna (USSR)); Guaraldo, C. (Istituto Nazionale di Fisica Nucleare, Frascati (Italy). Lab. Nazionale di Frascati); Lodi Rizzini, E. (Brescia Univ. (Italy). Dipt. di Automazione Industriale Istituto Nazionale di Fisica Nucleare, Turin (Italy)); Haatuft, A.; Halsteinslid, A.; Myklebost, K.; Olsen, J.M. (Bergen Univ. (Norway). Dept. of Physics); Breivik, F.O.; Jacobsen, T.; Soerensen, S.O. (Oslo Univ. (Norway). Physics Dept.); Balestra

    1990-11-26

    The pionic annihilation of antiprotons stopped on {sup 3}He nuclei in a self-shunted streamer chamber exposed to the antiproton beam of LEAR is studied. The data concern charged-particle multiplicity distributions, branching ratios for different final states, the probability of final-state interaction, {pi}{sup -}, {pi}{sup +}, p and d momentum spectra, like and unlike pion angular correlations, {pi} and other charged-particle angular correlations. The comparison of the {sup 3}He data with those obtained on {sup 1}H, {sup 2}H and {sup 4}He does not reveal relevant effects due to the increase of the nucleon number; the small differences can be seen as due to a weak final-state interaction. (orig.).

  16. Pionic annihilation of antiprotons stopped on 3He

    International Nuclear Information System (INIS)

    Bendiscioli, G.; Filippini, V.; Rotondi, A.; Salvini, P.; Venaglioni, A.; Bossolasco, S.; Bussa, M.P.; Busso, L.; Fava, L.; Ferrero, L.; Maggiora, A.; Panzieri, D.; Piragino, G.; Piragino, R.; Tosello, F.; Batusov, Yu.A.; Falomkin, I.V.; Pontecorvo, G.B.; Rozhdestvensky, A.M.; Sapozhnikov, M.G.; Tretyak, V.I.; Guaraldo, C.; Haatuft, A.; Halsteinslid, A.; Myklebost, K.; Olsen, J.M.; Zenoni, A.

    1990-01-01

    The pionic annihilation of antiprotons stopped on 3 He nuclei in a self-shunted streamer chamber exposed to the antiproton beam of LEAR is studied. The data concern charged-particle multiplicity distributions, branching ratios for different final states, the probability of final-state interaction, π - , π + , p and d momentum spectra, like and unlike pion angular correlations, π and other charged-particle angular correlations. The comparison of the 3 He data with those obtained on 1 H, 2 H and 4 He does not reveal relevant effects due to the increase of the nucleon number; the small differences can be seen as due to a weak final-state interaction. (orig.)

  17. Constraining heavy dark matter with cosmic-ray antiprotons

    Science.gov (United States)

    Cuoco, Alessandro; Heisig, Jan; Korsmeier, Michael; Krämer, Michael

    2018-04-01

    Cosmic-ray observations provide a powerful probe of dark matter annihilation in the Galaxy. In this paper we derive constraints on heavy dark matter from the recent precise AMS-02 antiproton data. We consider all possible annihilation channels into pairs of standard model particles. Furthermore, we interpret our results in the context of minimal dark matter, including higgsino, wino and quintuplet dark matter. We compare the cosmic-ray antiproton limits to limits from γ-ray observations of dwarf spheroidal galaxies and to limits from γ-ray and γ-line observations towards the Galactic center. While the latter limits are highly dependent on the dark matter density distribution and only exclude a thermal wino for cuspy profiles, the cosmic-ray limits are more robust, strongly disfavoring the thermal wino dark matter scenario even for a conservative estimate of systematic uncertainties.

  18. Precocious scaling in antiproton-proton scattering at low energies

    International Nuclear Information System (INIS)

    Ion, D.B.; Petrascu, C.; Topor Pop, V.; Popa, V.

    1993-08-01

    The scaling of the diffraction peak in antiproton-proton scattering has been investigated from nera threshold up to 3 GeV/c laboratory momenta. It was shown that the scaling of the differential cross sections are evidentiated with a surprising accuracy not only at high energies, but also at very low ones (e.g. p LAB = 0.1 - 0.5 GeV/c), beyond the resonance and exotic resonance regions. This precocious scaling strongly suggests that the s-channel helicity conservation (SCHC) can be a peculiar property that should be tested in antiproton-proton interaction not only at high energies but also at low energy even below p LAB = 1 GeV/c. (author). 36 refs, 9 figs

  19. Testing quantum chromodynamics in anti-proton reactions

    International Nuclear Information System (INIS)

    Brodsky, S.J.

    1987-10-01

    An experimental program with anti-protons at intermediate energy can serve as an important testing ground for QCD. Detailed predictions for exclusive cross sections at large momentum transfer based on perturbative QCD and the QCD sum rule form of the proton distribution amplitude are available for anti p p → γγ for both real and virtual photons. Meson-pair and lepton-pair final states also give sensitive tests of the theory. The production of charmed hadrons in exclusive anti p p channels may have a non-negligible cross section. Anti-proton interactions in a nucleus, particularly J/psi production, can play an important role in clarifying fundamental QCD issues, such as color transparency, critical length phenomena, and the validity of the reduced nuclear amplitude phenomenology

  20. The CERN Antiproton Collider Programme Accelerators and Accumulation Rings

    CERN Document Server

    Koziol, Heribert

    2004-01-01

    One of CERN's most daring and successful undertakings was the quest for the intermediate bosons, W and Z. In this paper, we describe the accelerator part of the venture which relied on a number of innovations: an extension of the budding method of stochastic cooling by many orders of magnitude; the construction of the Antiproton Accumulator, depending on several novel accelerator methods and technologies; major modifications to the 26 GeV PS Complex; and the radical conversion of the 300 GeV SPS, which just had started up as an accelerator, to a protonâ€"antiproton collider. The SPS Collider had to master the beamâ€"beam effect far beyond limits reached ever before and had to function in a tight symbiosis with the huge detectors UA1 and UA2.

  1. Antiprotons from dark matter annihilation in the Galaxy. Astrophysical uncertainties

    Energy Technology Data Exchange (ETDEWEB)

    Evoli, Carmelo [Chinese Academy of Sciences, Beijing (China). National Astronomical Observatories; Cholis, Ilias; Ullio, Piero [SISSA, Sezione di Trieste (Italy); INFN, Sezione di Trieste (Italy); Grasso, Dario [INFN, Sezione di Pisa (Italy); Maccione, Luca [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2011-08-15

    The latest years have seen steady progresses in WIMP dark matter (DM) searches, with hints of possible signals suggested by both direct and indirect detection experiments. Antiprotons can play a key role validating those interpretations since they are copiously produced by WIMP annihilations in the Galactic halo, and the secondary antiproton background produced by Cosmic Ray (CR) interactions is predicted with fair accuracy and matches the observed spectrum very well. Using the publicly available numerical DRAGON code, we reconsider antiprotons as a tool to constrain DM models discussing its power and limitations. We provide updated constraints on a wide class of annihilating DM models by comparing our predictions against the most up-to-date anti p measurements, taking also into account the latest spectral information on the p, He and other CR nuclei fluxes. Doing that, we probe carefully the uncertainties associated to both secondary and DM originated antiprotons, by using a variety of distinctively different assumptions for the propagation of CRs and for the DM distribution in the Galaxy. We find that the impact of the astrophysical uncertainties on constraining the DM properties can be much stronger, up to a factor of {proportional_to}50, than the one due to uncertainties on the DM distribution ({proportional_to}2-6). Remarkably, even reducing the uncertainties on the propagation parameters derived by local observables, non-local effects can still change DM model constraints even by 50%. Nevertheless, current anti p data place tight constraints on DM models, excluding some of those suggested in connection with indirect and direct searches. Finally we discuss the power of upcoming CR spectral data from the AMS-02 observatory to drastically reduce the uncertainties discussed in this paper and estimate the expected sensitivity of this instrument to some sets of DM models. (orig.)

  2. Physics at the Fermilab Tevatron Proton-Antiproton Collider

    International Nuclear Information System (INIS)

    Geer, S.

    1994-08-01

    These lectures discuss a selection of QCD and Electroweak results from the CDF and D0 experiments at the Fermilab Tevatron Proton-Antiproton Collider. Results are presently based on data samples of about 20 pb -1 at a center-of-mass energy of 1.8 TeV. Results discussed include jet production, direct photon production, W mass and width measurements, the triboson coupling, and most exciting of all, evidence for top quark production

  3. Antiproton-helium annihilation around 45 MeV/c

    International Nuclear Information System (INIS)

    Balestra, F.; Bassolasco, S.; Bussa, M.P.; Busso, L.; Ferrero, L.; Panzieri, D.; Piragino, G.; Tosello, F.; Barbieri, R.; Bendiscioli, G.; Filippini, V.; Rotondi, A.; Salvini, P.; Zenoni, A.; Batusov, Yu.A.; Falomkin, I.V.; Pontecorvo, G.B.; Rozhdestvensky, A.M.; Sapozhnikov, M.G.; Tretyak, V.I.; Breivik, F.O.; Jacobsen, T.; Soerensen, S.O.

    1989-01-01

    The anti p 4 He annihilation cross section averaged over the interval 40-50 MeV/c has been measured using a streamer chamber in a magnetic field. The measured value is 1342±250 mb. It agrees with a behaviour like 1/p of the annihilation cross section. Our result has been obtained at the lowest momentum achieved till now in measurements of antiproton annihilation in flight. (orig.)

  4. Antiproton-helium annihilation around 45 MeV/c

    Energy Technology Data Exchange (ETDEWEB)

    Balestra, F.; Bassolasco, S.; Bussa, M.P.; Busso, L.; Ferrero, L.; Panzieri, D.; Piragino, G.; Tosello, F. (Turin Univ. (Italy). Ist. di Fisica Generale; Istituto Nazionale di Fisica Nucleare, Turin (Italy)); Barbieri, R.; Bendiscioli, G.; Filippini, V.; Rotondi, A.; Salvini, P.; Zenoni, A. (Pavia Univ. (Italy). Dipt. di Fisica Nucleare e Teorica; Istituto Nazionale di Fisica Nucleare, Pavia (Italy)); Batusov, Yu.A.; Falomkin, I.V.; Pontecorvo, G.B.; Rozhdestvensky, A.M.; Sapozhnikov, M.G.; Tretyak, V.I. (Joint Inst. for Nuclear Research, Dubna (USSR)); Breivik, F.O.; Jacobsen, T.; Soerensen, S.O. (Oslo Univ. (Norway). Fysisk Inst.); Guaraldo, C.; Maggiora, A. (Istituto Nazionale di Fisica Nucleare, Frascati (Italy). Lab. Nazionale di Frascati); Haatuft, A.; Halsteinslid, A.; Myklebost, K.; Olsen, J.M. (Bergen Univ. (Norway). Dept. of Physics); Lodi Rizzini, E. (Brescia Univ. (Italy). Dipt. di Automazione Industriale); Masala, M. (Brescia Univ. (Italy). Dipt. di Automazione Ind

    1989-10-26

    The anti p{sup 4}He annihilation cross section averaged over the interval 40-50 MeV/c has been measured using a streamer chamber in a magnetic field. The measured value is 1342+-250 mb. It agrees with a behaviour like 1/p of the annihilation cross section. Our result has been obtained at the lowest momentum achieved till now in measurements of antiproton annihilation in flight. (orig.).

  5. Evidence of isospin effects in antiproton-nucleus annihilation

    International Nuclear Information System (INIS)

    Balestra, F.; Bossolasco, S.; Bussa, M.P.; Busso, L.; Ferrero, L.; Panzieri, D.; Piragino, G.; Tosello, F.; Barbieri, R.; Bendiscioli, G.; Rotondi, A.; Salvini, P.; Venaglioni, A.; Zenoni, A.; Batusov, Yu.A.; Falomkin, I.V.; Pontecorvo, G.B.; Rozhdestvensky, A.M.; Sapozhnikov, M.G.; Tretyak, V.I.; Guaraldo, C.; Maggiora, A.; Haatuft, A.; Halsteinslid, A.; Myklebost, K.; Olsen, J.M.; Breivik, F.O.; Jacobsen, T.; Soerensen, S.O.

    1989-01-01

    Antiproton- 3 He annihilation events at rest have been detected using a self-shunted streamer chamber. The ratio of the cross section for annihilation on neutrons and on protons has been measured (0.467±0.035). It is compared with other results from annihilation on free nucleons, deuterium, 3 He and 4 He. The low value of the ratio seems to indicate a strong isospin dependence of the antinucleon-nucleon P-wave amplitude. (orig.)

  6. Superconducting beam charge monitors for antiproton storage rings

    OpenAIRE

    Tympel, Volker; Neubert, Ralf; Seidel, Paul; Geithner, René; Golm, Jessica; Stöhlker, Thomas; Kurian, Febian; Sieber, Thomas; Schwickert, Marcus; Fernandes, Miguel

    2017-01-01

    A Cryogenic Current Comparator (CCC) is a new type of instruments for monitoring charged beams like ions or antiprotons. Using superconducting effects is it possible to create a nondestructive, contactless and easy to calibrate beam measurement system with a high current resolution in amplitude and time. The Meissner effect enables an effective magnetic shielding of the system. The screening current enables creation of DC-transformers and therefore a DC-current measurement system. The combina...

  7. Polarization of antiprotons by the Stern-Gerlach effect

    International Nuclear Information System (INIS)

    Kewisch, J.; Rossmanith, R.; Onel, Y.; Penzo, A.; Kreiser, H.

    1988-01-01

    A method to obtain polarized antiprotons in the low energy storage ring LEAR via spatial separation of opposite spin states is described in earlier papers (Y. Onel et al., 1986). We will discuss here in more detail a) the integration of the special magnets (spin splitter) into the LEAR optics and b) some first tracking results of particle and spin motion in these optics. (orig./HSI)

  8. Proton-antiproton interactions (experimental status of baryonium states)

    Energy Technology Data Exchange (ETDEWEB)

    Prakash, Y.

    1980-07-01

    Many experiments have been performed in the last few years to search for the existence of baryonium (baryon-antibaryon bound) states. The current status in this direction is reviewed. Prominent resonances such as the S-meson resonance, broad resonances, narrow resonances and states such as the strange baryonium states, exotic states, antiproton-proton states below threshold, six-quark states are explained. A summary of the experimental data with illustrations is presented in a table.

  9. A beam sweeping system for the Fermilab antiproton production target

    International Nuclear Information System (INIS)

    Bieniosek, F.M.

    1993-08-01

    In the Main Injector era beam intensities high enough to damage the antiproton production target will be available. In order to continue to operate with a tightly-focused primary beam spot on the target, and thus maintain yield, it will be necessary to spread the hot spot on the target by use of a beam sweeping system. This report summarizes the requirements for such a system, and addresses the issues involved in the design of a sweeping system

  10. Prospects for testing Lorentz and CPT symmetry with antiprotons

    Science.gov (United States)

    Vargas, Arnaldo J.

    2018-03-01

    A brief overview of the prospects of testing Lorentz and CPT symmetry with antimatter experiments is presented. The models discussed are applicable to atomic spectroscopy experiments, Penning-trap experiments and gravitational tests. Comments about the sensitivity of the most recent antimatter experiments to the models reviewed here are included. This article is part of the Theo Murphy meeting issue `Antiproton physics in the ELENA era'.

  11. Prospects for testing Lorentz and CPT symmetry with antiprotons.

    Science.gov (United States)

    Vargas, Arnaldo J

    2018-03-28

    A brief overview of the prospects of testing Lorentz and CPT symmetry with antimatter experiments is presented. The models discussed are applicable to atomic spectroscopy experiments, Penning-trap experiments and gravitational tests. Comments about the sensitivity of the most recent antimatter experiments to the models reviewed here are included.This article is part of the Theo Murphy meeting issue 'Antiproton physics in the ELENA era'. © 2018 The Author(s).

  12. The Antiproton Accumulator and Collector and the discovery of the W & Z intermediate vector bosons

    CERN Document Server

    Chohan, Vinod

    2016-01-01

    The following sections are included: Preface ; Brief outline of the overall scheme for antiprotons of the SPS as a collider ; Antiproton production and accumulation ; The AA and AC storage rings ; Stochastic cooling and stacking ; Post-acceleration of antiprotons and beams for SPS Collider ; Proton test beams for the AA and AC from the PS ; The W and Z discoveries and the Nobel Prize ; Accumulator performance ; Acknowledgements and conclusions ; References

  13. Commissioning of Fermilab's Electron Cooling System for 8-GeV Antiprotons

    CERN Document Server

    Nagaitsev, Sergei; Burov, Alexey; Carlson, Kermit; Gai, Wei; Gattuso, Consolato; Hu, Martin; Kazakevich, Grigory; Kramper, Brian J; Kroc, Thomas K; Leibfritz, Jerry; Prost, Lionel; Pruss, Stanley M; Saewert, Greg W; Schmidt, Chuck; Seletsky, Sergey; Shemyakin, Alexander V; Sutherland, Mary; Tupikov, Vitali; Warner, Arden

    2005-01-01

    A 4.3-MeV electron cooling system has been installed at Fermilab in the Recycler antiproton storage ring and is being currently commissioned. The cooling system is designed to assist accumulation of 8.9-GeV/c antiprotons for the Tevatron collider operations. This paper will report on the progress of the electron beam commissioning effort as well as on detailed plans of demonstrating the cooling of antiprotons.

  14. Bubble detector measurements of a mixed radiation field from antiproton annihilation

    International Nuclear Information System (INIS)

    Bassler, Niels; Knudsen, Helge; Moller, Soren Pape; Petersen, Jorgen B.; Rahbek, Dennis; Uggerhoj, Ulrik I.

    2006-01-01

    In the light of recent progress in the study of the biological potential of antiproton tumour treatment it is important to be able to characterize the neutron intensity arising from antiproton annihilation using simple, compact and reliable detectors. The intensity of fast neutrons from antiproton annihilation on polystyrene has been measured with bubble detectors and a multiplicity has been derived as well as an estimated neutron equivalent dose. Additionally the sensitivity of bubble detectors towards protons was measured

  15. Evaporative cooling of antiprotons and efforts to trap antihydrogen

    CERN Document Server

    Andresen, Gorm Bruun

    Evaporative cooling has proven to be an invaluable technique in atomic physics, allowing for the study of effects such as Bose-Einstein condensation. One main topic of this thesis is the first application of evaporative cooling to cold non-neutral plasmas stored in an ion trap. We (the ALPHA collaboration) have achieved cooling of a cloud of antiprotons to a temperature as low as 9 K, two orders of magnitude lowerthan ever directly measured previously. The measurements are well-described by appropriate rate equations for the temperature and number of particles. The technique has direct application to the ongoing attempts to produce trapped samples of antihydrogen. In these experiments the maximum trap depths are ex tremely shallow (~0.6 K for ground state atoms), and careful control of the trapped antiprotons and positrons used to form the (anti)atoms is essential to succes. Since 2006 powerful tools to diagnose and manipulate the antiproton and positron plasmas in the ALPHA apparatus have been developed and ...

  16. Antihydrogen formation by autoresonant excitation of antiproton plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Bertsche, William Alan, E-mail: bertsche@cern.ch [Swansea University, Department of Physics (United Kingdom); Andresen, G. B. [Aarhus University, Department of Physics and Astronomy (Denmark); Ashkezari, M. D. [Simon Fraser University, Department of Physics (Canada); Baquero-Ruiz, M. [University of California, Department of Physics (United States); Bowe, P. D. [Aarhus University, Department of Physics and Astronomy (Denmark); Carpenter, P. T. [Auburn University, Department of Physics (United States); Butler, E. [CERN, Physics Department (Switzerland); Cesar, C. L. [Universidade Federal do Rio de Janeiro, Instituto de Fisica (Brazil); Chapman, S. F. [University of California, Department of Physics (United States); Charlton, M.; Eriksson, S. [Swansea University, Department of Physics (United Kingdom); Fajans, J. [University of California, Department of Physics (United States); Friesen, T. [University of Calgary, Department of Physics and Astronomy (Canada); Fujiwara, M. C.; Gill, D. R. [TRIUMF (Canada); Gutierrez, A. [University of British Columbia, Department of Physics and Astronomy (Canada); Hangst, J. S. [Aarhus University, Department of Physics and Astronomy (Denmark); Hardy, W. N. [University of British Columbia, Department of Physics and Astronomy (Canada); Hayano, R. S. [University of Tokyo, Department of Physics (Japan); Hayden, M. E. [Simon Fraser University, Department of Physics (Canada); Collaboration: ALPHA Collaboration; and others

    2012-12-15

    In efforts to trap antihydrogen, a key problem is the vast disparity between the neutral trap energy scale ({approx} 50 {mu}eV), and the energy scales associated with plasma confinement and space charge ({approx}1 eV). In order to merge charged particle species for direct recombination, the larger energy scale must be overcome in a manner that minimizes the initial antihydrogen kinetic energy. This issue motivated the development of a novel injection technique utilizing the inherent nonlinear nature of particle oscillations in our traps. We demonstrated controllable excitation of the center-of-mass longitudinal motion of a thermal antiproton plasma using a swept-frequency autoresonant drive. When the plasma is cold, dense and highly collective in nature, we observe that the entire system behaves as a single-particle nonlinear oscillator, as predicted by a recent theory. In contrast, only a fraction of the antiprotons in a warm or tenuous plasma can be similarly excited. Antihydrogen was produced and trapped by using this technique to drive antiprotons into a positron plasma, thereby initiating atomic recombination. The nature of this injection overcomes some of the difficulties associated with matching the energies of the charged species used to produce antihydrogen.

  17. Antihydrogen formation by autoresonant excitation of antiproton plasmas

    International Nuclear Information System (INIS)

    Bertsche, William Alan; Andresen, G. B.; Ashkezari, M. D.; Baquero-Ruiz, M.; Bowe, P. D.; Carpenter, P. T.; Butler, E.; Cesar, C. L.; Chapman, S. F.; Charlton, M.; Eriksson, S.; Fajans, J.; Friesen, T.; Fujiwara, M. C.; Gill, D. R.; Gutierrez, A.; Hangst, J. S.; Hardy, W. N.; Hayano, R. S.; Hayden, M. E.

    2012-01-01

    In efforts to trap antihydrogen, a key problem is the vast disparity between the neutral trap energy scale (∼ 50 μeV), and the energy scales associated with plasma confinement and space charge (∼1 eV). In order to merge charged particle species for direct recombination, the larger energy scale must be overcome in a manner that minimizes the initial antihydrogen kinetic energy. This issue motivated the development of a novel injection technique utilizing the inherent nonlinear nature of particle oscillations in our traps. We demonstrated controllable excitation of the center-of-mass longitudinal motion of a thermal antiproton plasma using a swept-frequency autoresonant drive. When the plasma is cold, dense and highly collective in nature, we observe that the entire system behaves as a single-particle nonlinear oscillator, as predicted by a recent theory. In contrast, only a fraction of the antiprotons in a warm or tenuous plasma can be similarly excited. Antihydrogen was produced and trapped by using this technique to drive antiprotons into a positron plasma, thereby initiating atomic recombination. The nature of this injection overcomes some of the difficulties associated with matching the energies of the charged species used to produce antihydrogen.

  18. Measurement of cosmic ray antiprotons from 3.7 to 19 GeV

    International Nuclear Information System (INIS)

    Hof, M.; Pfeifer, C.; Menn, W.; Simon, M.; Golden, R.L.; Stochaj, S.J.; Basini, G.; Ricci, M.

    1996-02-01

    The antiproton to proton ratio in the cosmic rays has been measured in the energy range from 3.7 to 19 GeV. This measurement was carried out using a balloon-borne superconducting magnetic spectrometer along with a gas Cherenkov counter, an imaging calorimeter and a time of flight scintillator system. The measured antiproton to proton ratio was determined to be 1.24 (+0.68, -0.51)X 10 -4 . The present result along with other recent observations show that the observed abundances of antiprotons are consistent with models, in which antiprotons are produced as secondaries during the propagation of cosmic rays in the galaxy

  19. Time-dependent density functional calculation of the energy loss of antiprotons colliding with metallic nanoshells

    International Nuclear Information System (INIS)

    Quijada, M.; Borisov, A.G.; Muino, R.D.

    2008-01-01

    Time-dependent density functional theory is used to study the interaction between antiprotons and metallic nanoshells. The ground state electronic properties of the nanoshell are obtained in the jellium approximation. The energy lost by the antiproton during the collision is calculated and compared to that suffered by antiprotons traveling in metal clusters. The resulting energy loss per unit path length of material in thin nanoshells is larger than the corresponding quantity for clusters. It is shown that the collision process can be interpreted as the antiproton crossing of two nearly bi-dimensional independent metallic systems. (copyright 2008 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  20. Search for antiproton-nucleus states with (anti p,p) reactions

    International Nuclear Information System (INIS)

    Garreta, D.; Birien, P.; Bruge, G.; Chaumeaux, A.; Drake, D.M.; Janouin, S.; Legrand, D.; Lemaire, M.C.; Mayer, B.; Pain, J.; Peng, J.C.; Berrada, M.; Bocquet, J.P.; Monnand, E.; Mougey, J.; Perrin, P.

    1985-01-01

    We have studied (anti p,p) reactions on 12 C, 63 Cu, and 209 Bi to search for possible nuclear states formed by antiprotons and nuclei. The experiments used the 180 MeV antiproton beam from LEAR, and the high-resolution magnetic spectrometer, SPES II, to detect the outgoing protons. No evidence of antiproton-nucleus states was found. The gross features of the proton spectra are reasonably well described by intranuclear cascade model calculations, which consider proton emission following antiproton annihilations in the target nucleus. (orig.)

  1. A novel antiproton radial diagnostic based on octupole induced ballistic loss

    CERN Document Server

    Andresen, G.B.; Bowe, P.D.; Bray, C.C.; Butler, E.; Cesar, C.L.; Chapman, S.; Charlton, M.; Fajans, J.; Fujiwara, M.C.; Funakoshi, R.; Gill, D.R.; Hangst, J.S.; Hardy, W.N.; Hayano, R.S.; Hayden, M.E.; Humphries, A.J.; Hydomako, R.; Jenkins, M.J.; Jorgensen, L.V.; Kurchaninov, L.; Lambo, R.; Madsen, N.; Nolan, P.; Olchanski, K.; Olin, A.; Page, R.D.; Povilus, A.; Pusa, P.; Robicheaux, F.; Sarid, E.; Seif El Nasr, S.; Silveira, D.M.; Storey, J.W.; Thompson, R.I.; van der Werf, D.P.; Wurtele, J.S.; Yamazaki, Y.

    2008-01-01

    We report results from a novel diagnostic that probes the outer radial profile of trapped antiproton clouds. The diagnostic allows us to determine the profile by monitoring the time-history of antiproton losses that occur as an octupole field in the antiproton confinement region is increased. We show several examples of how this diagnostic helps us to understand the radial dynamics of antiprotons in normal and nested Penning-Malmberg traps. Better understanding of these dynamics may aid current attempts to trap antihydrogen atoms.

  2. A novel antiproton radial diagnostic based on octupole induced ballistic loss

    International Nuclear Information System (INIS)

    Andresen, G. B.; Bowe, P. D.; Hangst, J. S.; Bertsche, W.; Butler, E.; Charlton, M.; Humphries, A. J.; Jenkins, M. J.; Joergensen, L. V.; Madsen, N.; Werf, D. P. van der; Bray, C. C.; Chapman, S.; Fajans, J.; Povilus, A.; Wurtele, J. S.; Cesar, C. L.; Lambo, R.; Silveira, D. M.; Fujiwara, M. C.

    2008-01-01

    We report results from a novel diagnostic that probes the outer radial profile of trapped antiproton clouds. The diagnostic allows us to determine the profile by monitoring the time history of antiproton losses that occur as an octupole field in the antiproton confinement region is increased. We show several examples of how this diagnostic helps us to understand the radial dynamics of antiprotons in normal and nested Penning-Malmberg traps. Better understanding of these dynamics may aid current attempts to trap antihydrogen atoms

  3. Spectroscopy of antiprotonic helium atoms and its contribution to the fundamental physical constants

    Science.gov (United States)

    Hayano, Ryugo S.

    2010-01-01

    Antiprotonic helium atom, a metastable neutral system consisting of an antiproton, an electron and a helium nucleus, was serendipitously discovered, and has been studied at CERN’s antiproton decelerator facility. Its transition frequencies have recently been measured to nine digits of precision by laser spectroscopy. By comparing these experimental results with three-body QED calculations, the antiproton-to-electron massratio was determined as 1836.152674(5). This result contributed to the CODATA recommended values of the fundamental physical constants. PMID:20075605

  4. Capture, Electron-Cooling and Compression of Antiprotons in a Large Penning-Trap for Physics Experiments with an Ultra-Low Energy Extracted Antiproton Beam

    CERN Multimedia

    2002-01-01

    % PS200 \\\\ \\\\The availability of ultra-low energy antiprotons is a crucial ingredient for the execution of the gravity measurements PS200. We have developed a method to provide such low energy antiprotons based on a large Penning trap (the PS200 catching trap). This system can accept a fast-extracted pulse from LEAR, reduce the energy of the antiprotons in the pulse from 5.9~MeV to several tens of kilovolts using a degrading foil, and then capture the antiprotons in a large Penning trap. These antiprotons are cooled by electrons previously admitted to the trap and are collected in a small region at the center of the trap. We have demonstrated our capability to capture up to 1~million antiprotons from LEAR in a single shot, electron cool these antiprotons, and transfer up to 95\\% of them into the inner, harmonic region. A storage time in excess of 1 hour was observed. These results have been obtained with the cryogenic trap vacuum coupled to a room temperature vacuum at about l0$ ^- ^{1} ^0 $ Torr, which is an...

  5. LEAP: A balloon-borne search for low-energy cosmic ray antiprotons

    Science.gov (United States)

    Moats, Anne Rosalie Myers

    The LEAP (Low Energy Antiproton) experiment is a search for cosmic ray antiprotons in the 120 MeV to 1.2 GeV kinetic energy range. The motivation for this project was the result announced by Buffington et al. (1981) that indicated an anomalously high antiproton flux below 300 MeV; this result has compelled theorists to propose sources of primary antiprotons above the small secondary antiproton flux produced by high energy cosmic ray collisions with nuclei in the interstellar medium. LEAP consisted of the NMSU magnet spectrometer, a time-of-flight system designed at NASA-Goddard, two scintillation detectors, and a Cherenkov counter. Analysis of flight data performed by the high energy astrophysics group at Goddard Space Flight Center revealed no antiproton candidates found in the 120 MeV to 360 MeV range; 3 possible antiproton candidate events were found in the 500 MeV to 1.2 GeV range in an analysis done here at the University of Arizona. However, since it will be necessary to sharpen the calibration on all of the LEAP systems in order to positively identify these events as antiprotons, only an upper limit has been determined at present. Thus, combining the analyses performed at the University of Arizona and NASA-Goddard, 90 percent confidence upper limits of 3.5 x 10-5 in the 120 MeV to 360 MeV range and 2.3 x 10-4 in the 500 MeV to 1.2 GeV range for the antiproton/proton ratio is indicated by the LEAP results. LEAP disagrees sharply with the results of the Buffington group, indicating a low antiproton flux at these energies. Thus, a purely secondary antiproton flux may be adequate at low energies.

  6. View of the CERN Antiproton Decelerator (AD) and portrait of Prof. Tommy Eriksson, in charge of the AD machine.

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    The Antiproton Decelerator (AD) is a storage ring at the CERN laboratory in Geneva. It started operation in 2000. It decelerates antiprotons before sending them to several experiments studying antimatter : ALPHA, ASACUSA, ATRAP and ACE.

  7. Multiple collision effects on the antiproton production by high energy proton (100 GeV - 1000 GeV)

    International Nuclear Information System (INIS)

    Takahashi, Hiroshi; Powell, J.

    1987-01-01

    Antiproton production rates which take into account multiple collision are calculated using a simple model. Methods to reduce capture of the produced antiprotons by the target are discussed, including geometry of target and the use of a high intensity laser. Antiproton production increases substantially above 150 GeV proton incident energy. The yield increases almost linearly with incident energy, alleviating space charge problems in the high current accelerator that produces large amounts of antiprotons

  8. Radiotherapy; Strahlentherapie

    Energy Technology Data Exchange (ETDEWEB)

    Wannenmacher, M. [Heidelberg Univ., Mannheim (Germany). Abt. fuer Klinische Radiologie; Debus, J. [Univ. Heidelberg (Germany). Abt. Radioonkologie und Strahlentherapie; Wenz, F. (eds.) [Universitaetsklinikum Mannheim (Germany). Klinik fuer Strahlentherapie und Radioonkologie

    2006-07-01

    The book is focussed on the actual knowledge on the clinical radiotherapy and radio-oncology. Besides fundamental and general contributions specific organ systems are treated in detail. The book contains the following contributions: Basic principles, radiobiological fundamentals, physical background, radiation pathology, basics and technique of brachytherapy, methodology and technique of the stereotactic radiosurgery, whole-body irradiation, operative radiotherapy, hadron therapy, hpyerthermia, combined radio-chemo-therapy, biometric clinical studies, intensity modulated radiotherapy, side effects, oncological diagnostics; central nervous system and sense organs, head-neck carcinomas, breast cancer, thorax organs, esophagus carcinoma, stomach carcinoma, pancreas carcinoma, heptabiliary cancer and liver metastases, rectal carcinomas, kidney and urinary tract, prostate carcinoma, testicular carcinoma, female pelvis, lymphatic system carcinomas, soft tissue carcinoma, skin cancer, bone metastases, pediatric tumors, nonmalignant diseases, emergency in radio-oncology, supporting therapy, palliative therapy.

  9. Compression of a mixed antiproton and electron non-neutral plasma to high densities

    Science.gov (United States)

    Aghion, Stefano; Amsler, Claude; Bonomi, Germano; Brusa, Roberto S.; Caccia, Massimo; Caravita, Ruggero; Castelli, Fabrizio; Cerchiari, Giovanni; Comparat, Daniel; Consolati, Giovanni; Demetrio, Andrea; Di Noto, Lea; Doser, Michael; Evans, Craig; Fanì, Mattia; Ferragut, Rafael; Fesel, Julian; Fontana, Andrea; Gerber, Sebastian; Giammarchi, Marco; Gligorova, Angela; Guatieri, Francesco; Haider, Stefan; Hinterberger, Alexander; Holmestad, Helga; Kellerbauer, Alban; Khalidova, Olga; Krasnický, Daniel; Lagomarsino, Vittorio; Lansonneur, Pierre; Lebrun, Patrice; Malbrunot, Chloé; Mariazzi, Sebastiano; Marton, Johann; Matveev, Victor; Mazzotta, Zeudi; Müller, Simon R.; Nebbia, Giancarlo; Nedelec, Patrick; Oberthaler, Markus; Pacifico, Nicola; Pagano, Davide; Penasa, Luca; Petracek, Vojtech; Prelz, Francesco; Prevedelli, Marco; Rienaecker, Benjamin; Robert, Jacques; Røhne, Ole M.; Rotondi, Alberto; Sandaker, Heidi; Santoro, Romualdo; Smestad, Lillian; Sorrentino, Fiodor; Testera, Gemma; Tietje, Ingmari C.; Widmann, Eberhard; Yzombard, Pauline; Zimmer, Christian; Zmeskal, Johann; Zurlo, Nicola; Antonello, Massimiliano

    2018-04-01

    We describe a multi-step "rotating wall" compression of a mixed cold antiproton-electron non-neutral plasma in a 4.46 T Penning-Malmberg trap developed in the context of the AEḡIS experiment at CERN. Such traps are routinely used for the preparation of cold antiprotons suitable for antihydrogen production. A tenfold antiproton radius compression has been achieved, with a minimum antiproton radius of only 0.17 mm. We describe the experimental conditions necessary to perform such a compression: minimizing the tails of the electron density distribution is paramount to ensure that the antiproton density distribution follows that of the electrons. Such electron density tails are remnants of rotating wall compression and in many cases can remain unnoticed. We observe that the compression dynamics for a pure electron plasma behaves the same way as that of a mixed antiproton and electron plasma. Thanks to this optimized compression method and the high single shot antiproton catching efficiency, we observe for the first time cold and dense non-neutral antiproton plasmas with particle densities n ≥ 1013 m-3, which pave the way for an efficient pulsed antihydrogen production in AEḡIS.

  10. Jagiellonian University Drift Chamber Calibration and Track Reconstruction in the P349 Antiproton Polarization Experiment

    CERN Document Server

    Alfs, D; Moskal, P; Zieliński, M; Grzonka, D; Hauenstein, F; Kilian, K; Lersch, D; Ritman, J; Sefzick, T; Oelert, W; Diermaier, M; Widmann, E; Zmeskal, J; Wolke, M; Nadel-Turonski, P; Carmignotto, M; Horn, T; Mkrtchyan, H; Asaturyan, A; Mkrtchyan, A; Tadevosyan, V; Zhamkochyan, S; Malbrunot-Ettenauer, S; Eyrich, W; Zink, A

    2017-01-01

    The goal of the P349 experiment is to test whether the antiproton production process can be itself a source of antiproton polarization. In this article, we present the motivation and details of the performed measurement. We report on the status of the analysis focusing mainly on calibration of the drift chambers and 3d track reconstruction.

  11. The PS 200 catching trap: A new tool for ultra-low energy antiproton physics

    International Nuclear Information System (INIS)

    Holzscheiter, M.H.; Dyer, P.L.; King, N.S.P.; Lizon, D.C.; Morgan, G.L.; Schauer, M.M.; Schecker, J.A.; Hoibraten, S.; Lewis, R.A.; Otto, T.

    1994-01-01

    Approximately one million antiprotons have been trapped and electron cooled in the PS200 catching trap from a single fast extracted pulse from LEAR. The system is described in detail, different extraction schemes are discussed, and possible applications of this instrument to ultra-low energy atomic and nuclear physics with antiprotons are mentioned

  12. What can an antiproton and a nucleus learn from each other

    International Nuclear Information System (INIS)

    Garreta, D.

    1984-01-01

    This chapter attempts to show that the - p-nucleus interaction may provide very useful information, both about the elementary - NN interaction and about nuclear structure. Topics covered include simple features which make a low-energy antiproton an interesting probe of the nucleus; simple features which make a nucleus an interesting target for an antiproton; antiproton-nucleus elastic scattering; antiproton-nucleus inelastic scattering; proton knock-out reactions on nuclei; and annihilation of the antiprotons in nuclei. The aim of experiment PS184 at the Low-Energy Antiproton Ring (LEAR) is to provide accurate data with regard to the - p-nucleus interaction in the following areas: the angular distribution of antiprotons elastically scattered from 12 C, 40 Ca, and 208 Pb; the excitation energy spectra and some angular distributions of antiprotons inelastically scattered from 12 C, 40 Ca, and 208 Pb; and the excitation energy spectra for proton knock-out reaction on 6 Li, 45 Sc, 123 Sb, and 209 B; at forward angles

  13. Trapping of antiprotons -- a first step on the way to antihydrogen

    International Nuclear Information System (INIS)

    Holzscheiter, M.H.

    1993-01-01

    A first step towards producing and effectively utilizing antihydrogen atoms consists of trapping antiprotons. The immediate next step must then be to control, i.e. trap the produced antihydrogen. The current state of the art in trapping antiprotons and positrons is reviewed, and the challenges in trapping the resulting neutral particles are discussed

  14. Status of the analysis for the search of polarization in the antiproton production process

    International Nuclear Information System (INIS)

    Alfs, D.; Asaturyan, A.; Carmignotto, M.; Diermaier, M.; Eyrich, W.; Głowacz, B.; Grzonka, D.; Hauenstein, F.; Horn, T.; Kilian, K.; Malbrunot-Ettenauer, S.; Mkrtchyan, A.; Mkrtchyan, H.; Moskal, P.; Nadel-Turonski, P.; Oelert, W.; Ritman, J.; Sefzick, T.; Tadevosyan, V.; Widmann, E.; Wolke, M.; Zhamkochyan, S.; Zieliński, M.; Zink, A.; Zmeskal, J.

    2016-01-01

    The P-349 experiment aims to test whether for antiprotons the production process itself can be a source of polarization in view of the preparation of a polarized antiproton beam. In this article we present the details of performed measurements and report on the status of the ongoing analysis.

  15. Bubble detector measurements of a mixed radiation field from antiproton annihilation

    DEFF Research Database (Denmark)

    Bassler, Niels; Knudsen, Helge; Møller, Søren Pape

    2006-01-01

    In the light of recent progress in the study of the biological potential of antiproton tumour treatment it is important to be able to characterize the neutron intensity arising from antiproton annihilation using simple, compact and reliable detectors. The intensity of fast neutrons from antiproto...

  16. Constraints on Exotic Spin-Dependent Interactions Between Matter and Antimatter from Antiprotonic Helium Spectroscopy

    Science.gov (United States)

    Ficek, Filip; Fadeev, Pavel; Flambaum, Victor V.; Jackson Kimball, Derek F.; Kozlov, Mikhail G.; Stadnik, Yevgeny V.; Budker, Dmitry

    2018-05-01

    Heretofore undiscovered spin-0 or spin-1 bosons can mediate exotic spin-dependent interactions between standard model particles. Here, we carry out the first search for semileptonic spin-dependent interactions between matter and antimatter. We compare theoretical calculations and spectroscopic measurements of the hyperfine structure of antiprotonic helium to constrain exotic spin- and velocity-dependent interactions between electrons and antiprotons.

  17. Radiotherapy apparatus

    International Nuclear Information System (INIS)

    Leung, P.M.; Webb, H.P.J.

    1985-01-01

    This invention relates to apparatus for applying intracavitary radiotherapy. In previously-known systems radioactive material is conveyed to a desired location within a patient by transporting a chain of balls pneumatically to and from an appropriately inserted applicator. According to this invention a ball chain for such a purpose comprises several radioactive balls separated by non-radioactive tracer balls of radiographically transparent material of lower density and surface hardness than the radioactive balls. The invention also extends to radiotherapy treatment apparatus comprising a storage, sorting and assembly system

  18. Discriminating between antihydrogen and mirror-trapped antiprotons in a minimum-B trap

    CERN Document Server

    Amole, C; Ashkezari, M D; Baquero-Ruiz, M; Bertsche, W; Butler, E; Cesar, C L; Chapman, S; Charlton, M; Deller, A; Eriksson, S; Fajans, J; Friesen, T; Fujiwara, M C; Gill, D R; Gutierrez, A; Hangst, J S; Hardy, W N; Hayden, M E; Humphries, A J; Hydomako, R; Kurchaninov, L; Jonsell, S; Madsen, N; Menary, S; Nolan, P; Olchanski, K; Olin, A; Povilus, A; Pusa, P; Robicheaux, F; Sarid, E; Silveira, D M; So, C; Storey, J W; Thompson, R I; van der Werf, D P; Wurtele, J S

    2012-01-01

    Recently, antihydrogen atoms were trapped at CERN in a magnetic minimum (minimum-B) trap formed by superconducting octupole and mirror magnet coils. The trapped antiatoms were detected by rapidly turning off these magnets, thereby eliminating the magnetic minimum and releasing any antiatoms contained in the trap. Once released, these antiatoms quickly hit the trap wall, whereupon the positrons and antiprotons in the antiatoms annihilated. The antiproton annihilations produce easily detected signals; we used these signals to prove that we trapped antihydrogen. However, our technique could be confounded by mirror-trapped antiprotons, which would produce seemingly-identical annihilation signals upon hitting the trap wall. In this paper, we discuss possible sources of mirror-trapped antiprotons and show that antihydrogen and antiprotons can be readily distinguished, often with the aid of applied electric fields, by analyzing the annihilation locations and times. We further discuss the general properties of antipr...

  19. Slowing down of 100 keV antiprotons in Al foils

    Directory of Open Access Journals (Sweden)

    K. Nordlund

    2018-03-01

    Full Text Available Using energy degrading foils to slow down antiprotons is of interest for producing antihydrogen atoms. I consider here the slowing down of 100 keV antiprotons, that will be produced in the ELENA storage ring under construction at CERN, to energies below 10 keV. At these low energies, they are suitable for efficient antihydrogen production. I simulate the antihydrogen motion and slowing down in Al foils using a recently developed molecular dynamics approach. The results show that the optimal Al foil thickness for slowing down the antiprotons to below 5 keV is 910 nm, and to below 10 keV is 840 nm. Also the lateral spreading of the transmitted antiprotons is reported and the uncertainties discussed. Keywords: Antiprotons, Stopping power, Slowing down, Molecular dynamics

  20. Measurement of antiproton annihilation on Cu, Ag and Au with emulsion films

    International Nuclear Information System (INIS)

    Aghion, S.; Consolati, G.; Evans, C.; Ferragut, R.; Amsler, C.; Ariga, A.; Ariga, T.; Ereditato, A.; Bonomi, G.; Bräunig, P.; Demetrio, A.; Brusa, R.S.; Cabaret, L.; Comparat, D.; Caccia, M.; Castelli, F.; Caravita, R.; Noto, L. Di; Cerchiari, G.; Doser, M.

    2017-01-01

    The characteristics of low energy antiproton annihilations on nuclei (e.g. hadronization and product multiplicities) are not well known, and Monte Carlo simulation packages that use different models provide different descriptions of the annihilation events. In this study, we measured the particle multiplicities resulting from antiproton annihilations on nuclei. The results were compared with predictions obtained using different models in the simulation tools GEANT4 and FLUKA. For this study, we exposed thin targets (Cu, Ag and Au) to a very low energy antiproton beam from CERN's Antiproton Decelerator, exploiting the secondary beamline available in the AEgIS experimental zone. The antiproton annihilation products were detected using emulsion films developed at the Laboratory of High Energy Physics in Bern, where they were analysed at the automatic microscope facility. The fragment multiplicity measured in this study is in good agreement with results obtained with FLUKA simulations for both minimally and heavily ionizing particles.

  1. Measurement of antiproton annihilation on Cu, Ag and Au with emulsion films

    Science.gov (United States)

    Aghion, S.; Amsler, C.; Ariga, A.; Ariga, T.; Bonomi, G.; Bräunig, P.; Brusa, R. S.; Cabaret, L.; Caccia, M.; Caravita, R.; Castelli, F.; Cerchiari, G.; Comparat, D.; Consolati, G.; Demetrio, A.; Di Noto, L.; Doser, M.; Ereditato, A.; Evans, C.; Ferragut, R.; Fesel, J.; Fontana, A.; Gerber, S.; Giammarchi, M.; Gligorova, A.; Guatieri, F.; Haider, S.; Hinterberger, A.; Holmestad, H.; Huse, T.; Kawada, J.; Kellerbauer, A.; Kimura, M.; Krasnický, D.; Lagomarsino, V.; Lansonneur, P.; Lebrun, P.; Malbrunot, C.; Mariazzi, S.; Matveev, V.; Mazzotta, Z.; Müller, S. R.; Nebbia, G.; Nedelec, P.; Oberthaler, M.; Pacifico, N.; Pagano, D.; Penasa, L.; Petracek, V.; Pistillo, C.; Prelz, F.; Prevedelli, M.; Ravelli, L.; Rienaecker, B.; RØhne, O. M.; Rotondi, A.; Sacerdoti, M.; Sandaker, H.; Santoro, R.; Scampoli, P.; Simon, M.; Smestad, L.; Sorrentino, F.; Testera, G.; Tietje, I. C.; Vamosi, S.; Vladymyrov, M.; Widmann, E.; Yzombard, P.; Zimmer, C.; Zmeskal, J.; Zurlo, N.

    2017-04-01

    The characteristics of low energy antiproton annihilations on nuclei (e.g. hadronization and product multiplicities) are not well known, and Monte Carlo simulation packages that use different models provide different descriptions of the annihilation events. In this study, we measured the particle multiplicities resulting from antiproton annihilations on nuclei. The results were compared with predictions obtained using different models in the simulation tools GEANT4 and FLUKA. For this study, we exposed thin targets (Cu, Ag and Au) to a very low energy antiproton beam from CERN's Antiproton Decelerator, exploiting the secondary beamline available in the AEgIS experimental zone. The antiproton annihilation products were detected using emulsion films developed at the Laboratory of High Energy Physics in Bern, where they were analysed at the automatic microscope facility. The fragment multiplicity measured in this study is in good agreement with results obtained with FLUKA simulations for both minimally and heavily ionizing particles.

  2. Operational experience with bunch rotation momentum reduction in the Fermilab antiproton source

    International Nuclear Information System (INIS)

    Bharadwaj, V.; Griffin, J.E.; MacLachlan, J.A.; Martin, P.S.; Meisner, K.G.; Wildman, D.

    1987-01-01

    In the Fermilab antiproton accumulation system antiprotons are produced by the delivery of trains of 120 GeV proton bunches to a production target from which antiprotons are collected with mean energy 8 GeV (kinetic) and momentum spread Δrho/rho > 3%. The antiproton beam has the time structure of the incident protons. The proton bunch spacing-to-length ratio is made as large as possible (> 20:1) so that the resulting antiproton momentum spread may be reduced by ''bunch rotation'' in a ''debunching'' ring where time spread is exchanged for momentum spread. Details of these procedures are described elsewhere; in this paper the authors report on the efficacy of these procedures during routine operation

  3. Segmented scintillation detectors with silicon photomultiplier readout for measuring antiproton annihilations

    CERN Document Server

    Sótér, A.; Kobayashi, T.; Barna, D.; Horváth, D.; Hori, M.

    2014-01-01

    The Atomic Spectroscopy and Collisions Using Slow Antiprotons (ASACUSA) experiment at the Antiproton Decelerator (AD) facility of CERN constructed segmented scintillators to detect and track the charged pions which emerge from antiproton annihilations in a future superconducting radiofrequency Paul trap for antiprotons. A system of 541 cast and extruded scintillator bars were arranged in 11 detector modules which provided a spatial resolution of 17 mm. Green wavelength-shifting fibers were embedded in the scintillators, and read out by silicon photomultipliers which had a sensitive area of 1 x 1 mm^2. The photoelectron yields of various scintillator configurations were measured using a negative pion beam of momentum p ~ 1 GeV/c. Various fibers and silicon photomultipliers, fiber end terminations, and couplings between the fibers and scintillators were compared. The detectors were also tested using the antiproton beam of the AD. Nonlinear effects due to the saturation of the silicon photomultiplier were seen a...

  4. Proton-Proton and Proton-Antiproton Colliders

    CERN Document Server

    Scandale, Walter

    2014-01-01

    In the last five decades, proton–proton and proton–antiproton colliders have been the most powerful tools for high energy physics investigations. They have also deeply catalyzed innovation in accelerator physics and technology. Among the large number of proposed colliders, only four have really succeeded in becoming operational: the ISR, the SppbarS, the Tevatron and the LHC. Another hadron collider, RHIC, originally conceived for ion–ion collisions, has also been operated part-time with polarized protons. Although a vast literature documenting them is available, this paper is intended to provide a quick synthesis of their main features and key performance.

  5. Top Production at the Tevatron: The Antiproton Awakens

    Energy Technology Data Exchange (ETDEWEB)

    Bloom, Kenneth [Nebraska U.

    2017-07-01

    A long time ago, at a laboratory far, far away, the Fermilab Tevatron collided protons and antiprotons at $\\sqrt{s} = 1.96$ TeV. The CDF and D0 experiments each recorded datasets of about 10 fb$^{-1}$. As such experiments may never be repeated, these are unique datasets that allow for unique measurements. This presentation describes recent results from the two experiments on top-quark production rates, spin orientations, and production asymmetries, which are all probes of the $p\\bar{p}$ initial state.

  6. Pontecorvo reactions of two-body antiproton annihilation in deuterium

    International Nuclear Information System (INIS)

    Kondratyuk, L.A.; Sapozhnikov, M.G.

    1988-01-01

    Rare annihilation reactions for stopped antiprotons in deuterium, p-bard→π - p; K + Σ - ; K 0 Λ, are considered using the two-step model described by the triangle diagram. It was found that the probabilities, W, of these processes are very sensitive to the behaviour of the deuteron wave function at small distances as well as to the meson form factors. It appears that the ratios R(KX)=W(KX)/W(π - p) are much less model-dependent and are about 10 -2 for R(K 0 λ) and 10 -4 for R(K + Σ - ). 17 refs.; 1 fig.; 3 tabs

  7. Evaporative cooling of antiprotons for the production of trappable antihydrogen

    Energy Technology Data Exchange (ETDEWEB)

    Silveira, D. M.; Cesar, C. L. [Instituto de Fisica - Universidade Federal do Rio de Janeiro, 21941-972, Rio de Janeiro (Brazil); Andresen, G. B.; Bowe, P. D.; Hangst, J. S. [Department of Physics and Astronomy, Aarhus University, DK-8000 Aarhus C (Denmark); Ashkezari, M. D.; Hayden, M. E. [Department of Physics, Simon Fraser University, Burnaby BC, V5A 1S6 (Canada); Baquero-Ruiz, M.; Chapman, S.; Fajans, J.; Povilus, A.; So, C.; Wurtele, J. S. [Department of Physics, University of California, Berkeley, California 94720-7300 (United States); Bertsche, W. [School of Physics and Astronomy, University of Manchester, M13 9PL Manchester (United Kingdom) and Cockroft Institute, WA4 4AD Warrington (United Kingdom); Butler, E. [CERN, PH Department, CH-1211 Geneva 23 (Switzerland); Charlton, M.; Madsen, N.; Werf, D. P. van der [Department of Physics, College of Science, Swansea University, Swansea SA2 8PP (United Kingdom); Friesen, T.; Hydomako, R. [Department of Physics and Astronomy, University of Calgary AB, T2N 1N4 (Canada); and others

    2013-03-19

    We describe the implementation of evaporative cooling of charged particles in the ALPHA apparatus. Forced evaporation has been applied to cold samples of antiprotons held in Malmberg-Penning traps. Temperatures on the order of 10 K were obtained, while retaining a significant fraction of the initial number of particles. We have developed a model for the evaporation process based on simple rate equations and applied it succesfully to the experimental data. We have also observed radial re-distribution of the clouds following evaporation, explained by simple conservation laws. We discuss the relevance of this technique for the recent demonstration of magnetic trapping of antihydrogen.

  8. Commissioning of polarized-proton and antiproton beams at Fermilab

    International Nuclear Information System (INIS)

    Yokosawa, A.

    1988-01-01

    The author described the polarized-proton and polarized-antiproton beams up to 200 GeV/c at Fermilab. The beam line, called MP, consists of the 400-m long primary and 350-m long secondary beam line followed by 60-m long experimental hall. We discuss the characteristics of the polarized beams. The Fermilab polarization projects are designated at E-581/704 initiated and carried out by an international collaboration, Argonne (US), Fermilab (US), Kyoto-Kyushu-Hiroshima-KEK (Japan), LAPP (France), Northwestern University (US), Los Alamos Laboratory (US), Rice (US), Saclay (France), Serpukhov (USSR), INFN Trieste (Italy), and University of Texas (US)

  9. The antiproton depth–dose curve measured with alanine detectors

    CERN Document Server

    Bassler, Niels; Palmans, Hugo; Holzscheiter, Michael H; Kovacevic, Sandra

    2008-01-01

    n this paper we report on the measurement of the antiproton depth–dose curve, with alanine detectors. The results are compared with simulations using the particle energy spectrum calculated by FLUKA, and using the track structure model of Hansen and Olsen for conversion of calculated dose into response. A good agreement is observed between the measured and calculated relative effectiveness although an underestimation of the measured values beyond the Bragg-peak remains unexplained. The model prediction of response of alanine towards heavy charged particles encourages future use of the alanine detectors for dosimetry of mixed radiation fields.

  10. The Antiproton Depth Dose Curve Measured with Alanine Detectors

    DEFF Research Database (Denmark)

    Bassler, Niels; Hansen, Johnny Witterseh; Palmans, Hugo

    2008-01-01

    In this paper we report on the measurement of the antiproton depth dose curve, with alanine detectors. The results are compared with simulations using the particle energy spectrum calculated by FLUKA, and using the track structure model of Hansen et Olsen for conversion of calculated dose...... into response. A good agreement was observed between the measured and calculated relative effectiveness although a slight underestimation of the calculated values in the Bragg peak remains unexplained. The model prediction of response of alanine towards heavy charged particles encourages future use...... of the alanine detectors for dosimetry of mixed radiation fields....

  11. Electrodes for stochastic cooling of the FNAL antiproton source

    International Nuclear Information System (INIS)

    Voelker, F.

    1982-11-01

    AN electrode array for stochastic cooling is being developed for use on the FNAL antiproton source. With minor power handling modifications, the same electrodes can function as pickups or as kickers. When used as pickups, a large array is needed to increase the signal-to-noise ratio. Each electrode is one element of a pair of directional coupler loops that are mounted flush with the upper and lower walls of the beam chamber. The loops, fabricated from flat metal plates, are supported by specially shaped legs

  12. High resolution X-ray spectroscopy in light antiprotonic atoms

    CERN Document Server

    Borchert, G L; Augsburger, M A; Castelli, C M; Chatellard, D; Egger, J P; El-Khoury, P; Elble, M; Gorke, H; Gotta, D; Hauser, P R; Indelicato, P J; Kirch, K; Lenz, S; Nelms, N; Rashid, K; Schult, O W B; Siems, T; Simons, L M

    2000-01-01

    At the LEAR facility, CERN, antiprotonic L alpha transitions in light elements have been investigated with a focussing crystal spectrometer. The high resolution of the experiment allowed for the first time to resolve in pH/pH the 2/sup 3/P/sub 0/ state from the close-lying states 2/sup 3/P/sub 2/, 2/sup 1/P/sub 1/, and 2/sup 3/P /sub 1/. In pD the corresponding transitions were found to be more than an order of magnitude broader. To a large extent the results for pH support the meson exchange model. (15 refs).

  13. Production of hypernuclei in peripheral collisions of relativistic ions

    Energy Technology Data Exchange (ETDEWEB)

    Botvina, A.S., E-mail: a.botvina@gsi.de [Frankfurt Institute for Advanced Studies, J.-W. Goethe University, 60438 Frankfurt am Main (Germany); Institute for Nuclear Research, Russian Academy of Science, 117312 Moscow (Russian Federation); Gudima, K.K. [Institute of Applied Physics, Academy of Sciences of Moldova, MD-2028 Kishinev (Moldova, Republic of); Steinheimer, J. [Frankfurt Institute for Advanced Studies, J.-W. Goethe University, 60438 Frankfurt am Main (Germany); Mishustin, I.N. [Frankfurt Institute for Advanced Studies, J.-W. Goethe University, 60438 Frankfurt am Main (Germany); Kurchatov Institute, Russian Research Center, 123182 Moscow (Russian Federation); Pochodzalla, J.; Sanchez Lorente, A. [The Helmholtz Institute Mainz (HIM), Johann-Joachim-Becher-Weg 36, 55099 Mainz (Germany); Bleicher, M. [Frankfurt Institute for Advanced Studies, J.-W. Goethe University, 60438 Frankfurt am Main (Germany); Stoecker, H. [Frankfurt Institute for Advanced Studies, J.-W. Goethe University, 60438 Frankfurt am Main (Germany); GSI - Helmholtzzentrum fuer Schwerionenforschung GmbH, 62491 Darmstadt (Germany)

    2012-05-01

    Formation of hypernuclei in peripheral collisions of relativistic light and heavy ions is studied theoretically within the transport and statistical approaches. New mechanisms for the formation of strange nuclear systems via capture of hyperons by slightly excited spectator matter and their subsequent disintegration are investigated. These processes lead to production of specific and exotic hypernuclei, which may not be accessible in other reactions. Similar mechanisms processing via absorption of strange particles by nuclei can take place in reactions initiated by electrons, antiprotons and other hadrons. It is demonstrated that our approach is consistent with experimental data.

  14. Production of hypernuclei in peripheral collisions of relativistic ions

    International Nuclear Information System (INIS)

    Botvina, A.S.; Gudima, K.K.; Steinheimer, J.; Mishustin, I.N.; Pochodzalla, J.; Sanchez Lorente, A.; Bleicher, M.; Stoecker, H.

    2012-01-01

    Formation of hypernuclei in peripheral collisions of relativistic light and heavy ions is studied theoretically within the transport and statistical approaches. New mechanisms for the formation of strange nuclear systems via capture of hyperons by slightly excited spectator matter and their subsequent disintegration are investigated. These processes lead to production of specific and exotic hypernuclei, which may not be accessible in other reactions. Similar mechanisms processing via absorption of strange particles by nuclei can take place in reactions initiated by electrons, antiprotons and other hadrons. It is demonstrated that our approach is consistent with experimental data.

  15. Design of a High Luminosity 100 TeV Proton-Antiproton Collider

    Science.gov (United States)

    Oliveros Tautiva, Sandra Jimena

    Currently new physics is being explored with the Large Hadron Collider at CERN and with Intensity Frontier programs at Fermilab and KEK. The energy scale for new physics is known to be in the multi-TeV range, signaling the need for a future collider which well surpasses this energy scale. A 10 34 cm-2 s-1 luminosity 100 TeV proton-antiproton collider is explored with 7x the energy of the LHC. The dipoles are 4.5 T to reduce cost. A proton-antiproton collider is selected as a future machine for several reasons. The cross section for many high mass states is 10 times higher in pp than pp collisions. Antiquarks for production can come directly from an antiproton rather than indirectly from gluon splitting. The higher cross sections reduce the synchrotron radiation in superconducting magnets and the number of events per bunch crossing, because lower beam currents can produce the same rare event rates. Events are also more centrally produced, allowing a more compact detector with less space between quadrupole triplets and a smaller beta* for higher luminosity. To adjust to antiproton beam losses (burn rate), a Fermilab-like antiproton source would be adapted to disperse the beam into 12 different momentum channels, using electrostatic septa, to increase antiproton momentum capture 12 times. At Fermilab, antiprotons were stochastically cooled in one Debuncher and one Accumulator ring. Because the stochastic cooling time scales as the number of particles, two options of 12 independent cooling systems are presented. One electron cooling ring might follow the stochastic cooling rings for antiproton stacking. Finally antiprotons in the collider ring would be recycled during runs without leaving the collider ring, by joining them to new bunches with snap bunch coalescence and synchrotron damping. These basic ideas are explored in this work on a future 100 TeV proton-antiproton collider and the main parameters are presented.

  16. Design of a High Luminosity 100 TeV Proton Antiproton Collider

    Energy Technology Data Exchange (ETDEWEB)

    Oliveros Tuativa, Sandra Jimena [Univ. of Mississippi, Oxford, MS (United States)

    2017-04-01

    Currently new physics is being explored with the Large Hadron Collider at CERN and with Intensity Frontier programs at Fermilab and KEK. The energy scale for new physics is known to be in the multi-TeV range, signaling the need for a future collider which well surpasses this energy scale. A 10$^{\\,34}$ cm$^{-2}$ s$^{-1}$ luminosity 100 TeV proton-antiproton collider is explored with 7$\\times$ the energy of the LHC. The dipoles are 4.5\\,T to reduce cost. A proton-antiproton collider is selected as a future machine for several reasons. The cross section for many high mass states is 10 times higher in $p\\bar{p}$ than $pp$ collisions. Antiquarks for production can come directly from an antiproton rather than indirectly from gluon splitting. The higher cross sections reduce the synchrotron radiation in superconducting magnets and the number of events per bunch crossing, because lower beam currents can produce the same rare event rates. Events are also more centrally produced, allowing a more compact detector with less space between quadrupole triplets and a smaller $\\beta^{*}$ for higher luminosity. To adjust to antiproton beam losses (burn rate), a Fermilab-like antiproton source would be adapted to disperse the beam into 12 different momentum channels, using electrostatic septa, to increase antiproton momentum capture 12 times. At Fermilab, antiprotons were stochastically cooled in one Debuncher and one Accumulator ring. Because the stochastic cooling time scales as the number of particles, two options of 12 independent cooling systems are presented. One electron cooling ring might follow the stochastic cooling rings for antiproton stacking. Finally antiprotons in the collider ring would be recycled during runs without leaving the collider ring, by joining them to new bunches with snap bunch coalescence and synchrotron damping. These basic ideas are explored in this work on a future 100 TeV proton-antiproton collider and the main parameters are presented.

  17. Possible kaon and antiproton factory designs for TRIUMF

    Energy Technology Data Exchange (ETDEWEB)

    Craddock, M K [British Columbia Univ., Vancouver (Canada); Kost, C J; Richardson, J R [British Columbia Univ., Vancouver (Canada). TRIUMF Facility

    1979-12-01

    Two alternative designs based on proton synchrotrons and isochronous ring cyclotrons, respectively are considered for accelerating high currents (<30 ..mu..A) from TRIUMF (0.45 GeV) to energies high enough for the production of high fluxes of kaons (8-10 GeV) and antiprotons (25-30 GeV). The first synchrotron would be fast cycling at 20 Hz, with third harmonic flat-topping to aid in injection and extraction. The cw beam from TRIUMF would be extracted in 100-turn macropulses at 22 ..mu..sec intervals. With 400 ..mu..A in TRIUMF and injection over 8-20 % of the magnet cycle, 30-80 ..mu..A could be accelerated to 10 GeV. A second synchrotron would accelerate 30 ..mu..A to 30 GeV for production of antiprotons. The ring cyclotron option would also be built in two stages, 0.45 to 3 GeV (15 sectors, 10 m radius) and 3 to 8.5 GeV (30 sectors, 20 m radius). With superconducting magnets (5 T) the weight of steel could be kept below 2000 tons for each ring. Large field-free regions between the spiral ium ions, are obtained with an av the polarimetry installation is being carried out.

  18. Antiproton-hydrogen scattering at low-eV energies

    International Nuclear Information System (INIS)

    Morgan Jr., D.L.

    1993-01-01

    In the scattering of negative particles other than the electron by atoms at lab-frame energies around 10 eV, an elastic process termed 'brickwall scattering' might lead to a high probability for scattering angles around 180deg. For an antiproton slowing in hydrogen, this backward scattering would result in the loss of nearly all of its energy in a single collision, since it and a hydrogen atom have nearly the same mass. Such energy loss would have a significant effect on the energy distribution of antiprotons at energies where capture by the protons of hydrogen is possible and might, thereby, affect the capture rate and the distribution of capture states. In the semiclassical treatment of the problem with an adiabatic potential energy, brickwall scattering is indeed present, and with a substantial cross section. However, this model appears to underestimate inelastic processes. Based on calculations for negative muons on hydrogen atoms, these processes appear to occur for about the same impact parameters as brickwall scattering and thus substantially reduce its effect. (orig.)

  19. The International Facility for Antiproton and Ion Research FAIR

    International Nuclear Information System (INIS)

    Gutbrod, H. H.

    2008-01-01

    The proposed project FAIR (Facility for Antiproton and Ion Research) is an international accelerator facility of the next generation and will be built as a new company FAIR GmbH next to the site of GSI. About 15 countries have expressed their intention to become shareholders. FAIR builds on the experience and technological developments already made at the existing GSI facility, and at the FAIR partner institutes world wide and incorporates new technological concepts. At its heart is a double ring facility with a circumference of 1100 meters. A system of cooler-storage rings for effective beam cooling at high energies and various experimental halls will be connected to the facility. The existing GSI accelerators - together with the planned proton-linac - serve as injector for the new facility. The double-ring synchrotron will provide ion beams of unprecedented intensities as well as of considerably increased energy. Thereby intense beams of secondary beams - unstable nuclei or antiprotons - can be produced. The system of storage-cooler rings allows the quality of these secondary beams - their energy spread and emittance - to be drastically improved. Moreover, in connection with the double ring synchrotron, an efficient parallel operation of up to four scientific programs can be realized at a time. The project is based on many technological innovations, the most important of which are five beam properties: Highest Beam Intensities, Brilliant Beam Quality, Higher Beam Energies, Highest Beam Power, Parallel Operation

  20. Precision tests of CPT invariance with single trapped antiprotons

    Energy Technology Data Exchange (ETDEWEB)

    Ulmer, Stefan [RIKEN, Ulmer Initiative Research Unit, Wako, Saitama (Japan); Collaboration: BASE-Collaboration

    2015-07-01

    The reason for the striking imbalance of matter and antimatter in our Universe has yet to be understood. This is the motivation and inspiration to conduct high precision experiments comparing the fundamental properties of matter and antimatter equivalents at lowest energies and with greatest precision. According to theory, the most sensitive tests of CPT invariance are measurements of antihydrogen ground-state hyperfine splitting as well as comparisons of proton and antiproton magnetic moments. Within the BASE collaboration we target the latter. By using a double Penning trap we performed very recently the first direct high precision measurement of the proton magnetic moment. The achieved fractional precision of 3.3 ppb improves the currently accepted literature value by a factor of 2.5. Application of the method to a single trapped antiproton will improve precision of the particles magnetic moment by more than a factor of 1000, thus providing one of the most stringent tests of CPT invariance. In my talk I report on the status and future perspectives of our efforts.

  1. Interstitial radiotherapy

    International Nuclear Information System (INIS)

    Scardino, P.T.; Bretas, F.

    1987-01-01

    The authors now have 20 years of experience with modern techniques of brachytherapy. The large number of patients treated in medical centers around the world and the widespread use of this type of radiotherapy have provided us with substantial information about the indications and contraindications, advantages and disadvantages, pitfalls and complications, as well as the results of these techniques. Although the focus of this review is the experience at Baylor using the combined technique of gold seed implantation plus external beam irradiation, the alternative forms of brachytherapy will be described and compared. The authors' intention is to provide the busy clinician with a succinct and informative review indicating the status of modern interstitial radiotherapy and describing day-to-day approach and results

  2. Palliative Radiotherapy

    International Nuclear Information System (INIS)

    Salinas, J.

    2003-01-01

    Palliative care does not attempt to prolong survival but to the achieve the highest quality of life both for the patient and their family covering their physical, psychological, social and spiritual needs. Radiotherapy (RT), one of the most important therapeutic modalities, has a great significance in palliative medicine for cancer since it attempts to reduce as much as possible the acute reaction associated with the treatment for the patient. (Author)

  3. Measurements of cascade times of antiprotons in molecular hydrogen and helium

    CERN Document Server

    Bianconi, A; Corradini, M; Donzella, A; Gómez, G; Lodi-Rizzini, E; Venturelli, L; Vilar, R; Zenoni, A; Bertin, A; Bruschi, M; Capponi, M; De Castro, S; Donà, R; Galli, D; Giacobbe, B; Marconi, U; Massa, I; Piccinini, M; Semprini-Cesari, N; Spighi, R; Vagnoni, V M; Vecchi, S; Villa, M; Vitale, A; Zoccoli, A; Cicalò, C; De Falco, A; Masoni, A; Puddu, G; Serci, S; Usai, G L; Gorchakov, O E; Prakhov, S N; Rozhdestvensky, A M; Tretyak, V I; Poli, M; Gianotti, P; Guaraldo, C; Lanaro, A; Lucherini, V; Petrascu, C; Ableev, V G; Ricci, R A; Vannucci, Luigi; Filippini, V; Fontana, A; Montagna, P; Rotondi, A; Salvini, P; Mirfakhraee, N; Bussa, M P; Busso, L; Cerello, P G; Denisov, O Yu; Ferrero, L; Garfagnini, R; Grasso, A; Maggiora, A; Panzarasa, A; Panzieri, D; Tosello, F; Botta, E; Bressani, Tullio; Calvo, D; Costa, S; D'Isep, F; Feliciello, A; Filippi, A; Marcello, S; Agnello, M; Iazzi, F; Minetti, B; Tessaro, S; Santi, L

    2000-01-01

    The OBELIX experiment at CERN collected samples of antiproton annihilations at rest in different gaseous targets, such as hydrogen, deuterium and helium. We analyze a set of the Obelix data using a new technique for measuring, for the first time, the cascade times independent of the capture energy and of the antiproton stopping power. We report on measurements of the cascade times for hydrogen at 3.4, 5.8, 9.8 and 150 mbar and for helium at 8.2, 50 and 150 mbar pressure. An estimate of the antiproton capture energy in hydrogen is also presented. (12 refs).

  4. Cryogenic tunable microwave cavity at 13GHz for hyperfine spectroscopy of antiprotonic helium

    International Nuclear Information System (INIS)

    Sakaguchi, J.; Gilg, H.; Hayano, R.S.; Ishikawa, T.; Suzuki, K.; Widmann, E.; Yamaguchi, H.; Caspers, F.; Eades, J.; Hori, M.; Barna, D.; Horvath, D.; Juhasz, B.; Torii, H.A.; Yamazaki, T.

    2004-01-01

    For the precise measurement of the hyperfine structure of antiprotonic helium, microwave radiation of 12.9GHz frequency is needed, tunable over +/-100MHz. A cylindrical microwave cavity is used whose front and rear faces are meshed to allow the antiprotons and laser beams to enter. The cavity is embedded in a cryogenic helium gas target. Frequency tuning of ∼300MHz with Q values of 2700-3000 was achieved using over-coupling and an external triple stub tuner. We also present Monte-Carlo simulations of the stopping distribution of antiprotons in the low-density helium gas using the GEANT4 package with modified energy loss routines

  5. Possibility of resonant capture of antiprotons by highly charged hydrogenlike ions

    International Nuclear Information System (INIS)

    Genkin, M.; Lindroth, E.

    2009-01-01

    Recently, an experimental setup was proposed by Lapierre et al. which would allow antiprotons and highly charged ions to collide repeatedly in an electron beam ion trap (EBIT) due to a nested trap configuration. As mentioned by the authors, such a setup may open the possibility to study antiproton capture into well-defined states through a resonant process which involves simultaneous electron excitation. In the present work, we give some theoretical estimations of the feasibility of that process. It appears that the exotic dielectronic-like process of resonant anti-proton capture in highly charged ions does not seem to be completely out of reach

  6. Two photon laser spectroscopy of antiprotonic helium atoms at CERN’s AD

    CERN Document Server

    Hori, M

    2014-01-01

    The ASACUSA collaboration of CERN has carried out two-photon laser spectroscopy of antiprotonic helium atoms using counter-propagating ultraviolet laser beams. This excited some non-linear transitions of the antiproton at the wavelengths λ = 139.8–197.0 nm, in a way that reduced the thermal Doppler broadening of the observed resonances. The resulting narrow spectral lines allowed the measurement of three transition frequencies with fractional precisions of 2.3–5 parts in 109. By comparing these values with three-body QED calculations, the antiproton-to-electron mass ratio was derived as 1836.1526736(23). We briefly review these results.

  7. Conformation radiotherapy and conformal radiotherapy

    International Nuclear Information System (INIS)

    Morita, Kozo

    1999-01-01

    In order to coincide the high dose region to the target volume, the 'Conformation Radiotherapy Technique' using the multileaf collimator and the device for 'hollow-out technique' was developed by Prof. S. Takahashi in 1960. This technique can be classified a type of 2D-dynamic conformal RT techniques. By the clinical application of this technique, the late complications of the lens, the intestine and the urinary bladder after radiotherapy for the maxillary cancer and the cervical cancer decreased. Since 1980's the exact position and shape of the tumor and the surrounding normal tissues can be easily obtained by the tremendous development of the CT/MRI imaging technique. As a result, various kinds of new conformal techniques such as the 3D-CRT, the dose intensity modulation, the tomotherapy have been developed since the beginning of 1990'. Several 'dose escalation study with 2D-/3D conformal RT' is now under way to improve the treatment results. (author)

  8. Survey and alignment of the Fermilab recycler antiproton storage ring

    International Nuclear Information System (INIS)

    Arics, Babatunde O.O.

    1999-01-01

    In June of 1999 Fermilab commissioned a newly constructed antiproton storage ring, the 'Recycler Ring', in the Main Injector tunnel directly above the Main Injector beamline. The Recycler Ring is a fixed 8 GeV kinetic energy storage ring and is constructed of strontium ferrite permanent magnets. The 3319.4-meter-circumference Recycler Ring consists of 344 gradient magnets and 100 quadrupoles all of which are permanent magnets. This paper discusses the methods employed to survey and align these permanent magnets within the Recycler Ring with the specified accuracy. The Laser Tracker was the major instrument used for the final magnet alignment. The magnets were aligned along the Recycler Ring with a relative accuracy of ±0.25 mm. (author)

  9. Exploring antihyperons potentials in nuclei by antiproton-nucleon reactions

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez Lorente, Alicia [Helmholtz Institut Mainz (Germany); Collaboration: PANDA-Collaboration

    2015-07-01

    The exclusive production of hyperon-Antihyperon pairs close to their production threshold in antiproton-nucleus collisions offers a unique and hitherto unexplored opportunity to study the behaviour of Antihyperons in nuclei. For the first time we analyse these reactions in a microscopic transport model using the Giessen Boltzmann-Uehling-Uhlenbeck Transportmodel (GiBUU). We find a substantial sensitivity of transverse momentum correlations of coincident AntiLambda-Lambda-pairs to the assumed depth of the AntiLambda potential. Rather than diminishing this effect, secondary scattering effects which are more pronounced at deeper AntiLambda potentials enhance this sensitivity. Because of the high cross section for this process and the simplicity of this method our results pave the way for experimental studies at the FAIR facility.

  10. Light quark spectroscopy at the Fermilab antiproton accumulator

    International Nuclear Information System (INIS)

    Armstrong, T.; Bettoni, D.; Bharadwaj, V.; Biino, C.; Borreani, G.; Broemmelsiek, D.; Buzzo, A.; Calabrese, R.; Ceccucci, A.; Cester, R.; Church, M.; Dalpiaz, P.F.; Dibenedetto, R.; Dimitroyannis, D.; Fabbri, M.G.; Fast, J.; Gianoli, A.; Ginsburg, C.; Gollwitzer, K.; Hahn, A.; Hasan, M.A.; Hsueh, S.; Lewis, R.; Luppi, E.; Macri, M.; Majewska, A.; Mandelkern, M.; Marchetto, F.; Marinelli, M.; Marques, J.; Marsh, W.; Martini, M.; Masuzawa, M.; Menichetti, E.; Migliori, A.; Mussa, R.; Pallavicini, M.; Palestini, S.; Pastrone, N.; Patrignani, C.; Peoples, J. Jr.; Pesando, L.; Petrucci, F.; Pia, M.G.; Pordes, S.; Rapidis, P.; Ray, R.; Reid, J.; Rinaudo, G.; Roccuzzo, B.; Rosen, J.L.; Santroni, A.; Sarmiento, M.; Savrie, M.; Scalisi, A.; Schultz, J.; Seth, K.K.; Smith, A.; Smith, G.A.; Sozzi, M.; Trokenheim, S.; Weber, M.; Werkema, S.; Zhang, Y.; Zhao, J.L.; Zioulas, G.

    1993-01-01

    Fermilab-experiment E-760 has confirmed the f 2 (1520) state in the 3π 0 final state in antiproton-proton annihilations in-flight (∼3.0 to 3.6 GeV c.m. energy), seen previously by Crystal Barrel and other groups at CERN at rest. The f 2 (1520) is also seen in its 2π 0 decay mode in the 2π 0 η channel and 2η decay mode in the π 0 2η channel. There are indications of this state in the 3η decay channel. The invariant mass spectrum is rich in states near 2 GeV, and amplitude and spin/parity analysis of the Dalitz plot is in progress in this mass region. (orig.)

  11. Proton-Antiproton Annihilation into Neutral Strange Mesons

    Science.gov (United States)

    Ritter, J.; Bertolotto, L.; Buzzo, A.; Debevec, P.; Drijard, D.; Easo, S.; Eisenstein, R. A.; Evangelista, C.; Eyrich, W.; Fearnley, T.; Ferro-Luzzi, M.; Fischer, H.; Franz, J.; Geyer, R.; Hamann, N. H.; Harris, P. G.; Hertzog, D. W.; Hughes, S. A.; Johansson, A.; Johansson, T.; Jones, R. T.; Kilian, K.; Kirsebom, K.; Klett, A.; Korsmo, H.; Lo Vetere, M.; Macri, M.; Marinelli, M.; Moosburger, M.; Mouëllic, B.; Oelert, W.; Ohlsson, S.; Palano, A.; Passaggio, S.; Perreau, J.-M.; Pia, M. G.; Pomp, S.; Price, M.; Reimer, P. E.; Ritter, J.; Robutti, E.; Röhrich, K.; Rook, M.; Sefzick, T.; Rössle, E.; Santroni, A.; Schmitt, H.; Steinkamp, O.; Stinzing, F.; Stugu, B.; Tayloe, R.; Tscheulin, M.; Urban, H. J.; Wirth, H.; Zipse, H.; Jetset (Ps202) Collaboration:

    1997-06-01

    In a search for gluonic hadrons, the formation channels p¯p → K sK s, p¯p → ηη, p¯p → π 0η and p¯p → π 0π 0 were studied in the mass range from 2.1 to 2.4 GeV using the Jetset (PS202) detector and an internal molecular hydrogen cluster jet target installed in the Low Energy Antiproton Ring (LEAR) at CERN. Cross sections for p¯p → K sK s have been obtained and limits are set on the non-observation of the ξ(2230). Conversely, we find evidence for a narrow signal in a preliminary analysis of our p¯p → ηη data consistent with a narrow ξ(2230).

  12. Proton-antiproton annihilation into neutral strange mesons

    Energy Technology Data Exchange (ETDEWEB)

    Ritter, J. [Illinois Univ., Urbana (United States). Loomis Lab.; Bertolotto, L.; Buzzo, A.; Debevec, P.; Drijard, D.; Easo, S.; Eisenstein, R.A.; Evangelista, C.; Eyrich, W.; Fearnley, T.; Ferro-Luzzi, M.; Fischer, H.; Franz, J.; Geyer, R.; Hamann, N.H.; Harris, P.G.; Hertzog, D.W.; Hughes, S.A.; Johansson, A.; Johansson, T.; Jones, R.T.; Kilian, K.; Kirsebom, K.; Klett, A.; Korsmo, H.; Lo Vetere, M.; Macri, M.; Marinelli, M.; Moosburger, M.; Mouellic, B.; Oelert, W.; Ohlsson, S.; Palano, A.; Passaggio, S.; Perreau, J.-M.; Pia, M.G.; Pomp, S.; Price, M.; Reimer, P.E.; Robutti, E.; Roehrich, K.; Rook, M.; Sefzick, T.; Roessle, E.; Santroni, A.; Schmitt, H.; Steinkamp, O.; Stinzing, F.; Stugu, B.; Tayloe, R.; Tscheulin, M.; Urban, H.J.; Wirth, H.; Zipse, H.; JETSET Collaboration

    1997-06-01

    In a search for gluonic hadrons, the formation channels pp{yields}K{sub S}K{sub S}, pp{yields}{eta}{eta}, pp{yields}{pi}{sup 0}{eta} and pp{yields}{pi}{sup 0}{pi}{sup 0} were studied in the mass range from 2.1 to 2.4 GeV using the Jetset (PS202) detector and an internal molecular hydrogen cluster jet target installed in the Low Energy Antiproton Ring (LEAR) at CERN. Cross sections for pp{yields}K{sub S}K{sub S} have been obtained and limits are set on the non-observation of the {xi}(2230). Conversely, we find evidence for a narrow signal in a preliminary analysis of our pp{yields}{eta}{eta} d ata consistent with a narrow {xi}(2230). (orig.).

  13. Proton-antiproton annihilation into neutral strange mesons

    International Nuclear Information System (INIS)

    Ritter, J.; Bertolotto, L.; Buzzo, A.; Debevec, P.; Drijard, D.; Easo, S.; Eisenstein, R.A.; Evangelista, C.; Eyrich, W.; Fearnley, T.; Ferro-Luzzi, M.; Fischer, H.; Franz, J.; Geyer, R.; Hamann, N.H.; Harris, P.G.; Hertzog, D.W.; Hughes, S.A.; Johansson, A.; Johansson, T.; Jones, R.T.; Kilian, K.; Kirsebom, K.; Klett, A.; Korsmo, H.; Lo Vetere, M.; Macri, M.; Marinelli, M.; Moosburger, M.; Mouellic, B.; Oelert, W.; Ohlsson, S.; Palano, A.; Passaggio, S.; Perreau, J.-M.; Pia, M.G.; Pomp, S.; Price, M.; Reimer, P.E.; Robutti, E.; Roehrich, K.; Rook, M.; Sefzick, T.; Roessle, E.; Santroni, A.; Schmitt, H.; Steinkamp, O.; Stinzing, F.; Stugu, B.; Tayloe, R.; Tscheulin, M.; Urban, H.J.; Wirth, H.; Zipse, H.

    1997-01-01

    In a search for gluonic hadrons, the formation channels pp→K S K S , pp→ηη, pp→π 0 η and pp→π 0 π 0 were studied in the mass range from 2.1 to 2.4 GeV using the Jetset (PS202) detector and an internal molecular hydrogen cluster jet target installed in the Low Energy Antiproton Ring (LEAR) at CERN. Cross sections for pp→K S K S have been obtained and limits are set on the non-observation of the ξ(2230). Conversely, we find evidence for a narrow signal in a preliminary analysis of our pp→ηη d ata consistent with a narrow ξ(2230). (orig.)

  14. Possible kaon and antiproton factory designs for TRIUMF

    International Nuclear Information System (INIS)

    Craddock, M.K.; Kost, C.J.; Richardson, J.R.

    1979-01-01

    Two alternative designs based on proton synchrotrons and isochronous ring cyclotrons, respectively are considered for accelerating high currents (<30 μA) from TRIUMF (0.45 GeV) to energies high enough for the production of high fluxes of kaons (8-10 GeV) and antiprotons (25-30 GeV). The first synchrotron would be fast cycling at 20 Hz, with third harmonic flat-topping to aid in injection and extraction. The cw beam from TRIUMF would be extracted in 100-turn macropulses at 22 μsec intervals. With 400 μA in TRIUMF and injection over 8-20 % of the magnet cycle, 30-80 μA could be accelerated to 10 GeV. A second synchrotron would accelerate 30 μA to 30 GeV for production of antiprotons. The ring cyclotron option would also be built in two stages, 0.45 to 3 GeV (15 sectors, 10 m radius) and 3 to 8.5 GeV (30 sectors, 20 m radius). With superconducting magnets (5 T) the weight of steel could be kept below 2000 tons for each ring. Large field-free regions between the spiral sector magnets allow room for multiple SIN-style accelerating cavities, permitting energy gains of many MeV/turn. Second or third harmonic cavities and the phase compression effect help in achieving separated turn extraction. Up to 100 % of the beam in TRIUMF could be accelerated to 8.5 GeV. (auth)

  15. Possible kaon and antiproton factory designs for TRIUMF

    International Nuclear Information System (INIS)

    Craddock, M.K.; Kost, C.J.; Richardson, J.R.

    1979-11-01

    Two alternative designs based on proton synchrotrons and isochronous ring cyclotrons, respectively are considered for accelerating high currents (>=30 μA) from TRIUMF (0.45 GeV) to energies high enough for the production of high fluxes of kaons (8-10 GeV) and antiprotons (25-30 GeV). The first synchrotron would be fast cycling at 20 Hz, with third harmonic flat-topping to aid in injection and extraction. The cw beam from TRIUMF would be extracted in 100-turn macropulses at 22 μsec intervals. With 400 μA in TRIUMF and injection over 8-20% of the magnet cycle, 30-80 μA could be accelerated to 10 GeV. A second synchrotron would accelerate 30 μA to 30 GeV for production of antiprotons. The ring cyclotron option would also be built in two stages, 0.45 to 3 GeV (15 sectors, 10 m radius) and 3 to 8.5 GeV (30 sectors, 20 m radius). With superconducting magnets (5 T) the weight of steel could be kept below 2000 tons for each ring. Large field-free regions between the spiral sector magnets allow room for multiple SIN-style accelerating cavities, permitting energy gains of many MeV/turn. Second or third harmonic cavities and the phase compression effect help in achieving separated turn extraction. Up to 100% of the beam in TRIUMF could be accelerated to 8.5 GeV. (auth)

  16. Postmastectomy radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Shikama, Naoto; Koguchi, Masahiko; Sasaki, Shigeru; Kaneko, Tomoki; Shinoda, Atsunori; Nishikawa, Atsushi [Shinshu Univ., Matsumoto, Nagano (Japan). School of Medicine

    2000-10-01

    Since there have been few reports on postmastectomy radiotherapy having a high evidence level in Japan, the significance of postoperative radiotherapy and the irradiation techniques were reviewed based on reports from Western countries. Authors focused on the indications for postoperative irradiation, irradiation methods (irradiation sites, irradiation techniques; prosthetics, methods of irradiating the chest wall and lymph nodes, timing of irradiation), and complications, and discuss them. The factors thought to be adaptable to postmastectomy radiotherapy have been listed. Axillary lymph node metastasis and the size of the primary focus are thought to be important factors in locoregional recurrence. The chest wall and the supraclavicular lymph nodes are the usual sites of irradiation after mastectomy. The irradiation method consists of tangential irradiation of the chest wall and single-field irradiation of the supraclavicular lymph nodes, with 46-50 Gy in fractional doses of 1.8-2 Gy x 5/w is administered for 4.5-5.5 weeks. The timing of irradiation in the West is generally after chemotherapy. Adverse radiation effects include ischemic heart disease, pneumonitis, arm edema, rib fractures, and brachial plexus paralysis. The frequency of these complications is increased by the combined use of chemotherapy or surgery. The breast cancer cure rate in Japan is generally better than in the West. It remains to be determined whether the clinical data from Europe and America are applicable to the treatment of breast cancer in Japan. To address this issue, a clinical investigation should be performed in Japan with close cooperation between surgeons, physicians, pathologists, and radiotherapists. (K.H.)

  17. Approximation of antiproton spectra in pp- and pA collisions

    International Nuclear Information System (INIS)

    Demidova, E.V.; Sibirtsev, A.A.

    1989-01-01

    Phenomenological expressions, describing the inclusive cross sections of antiproton production in proton-proton and proton-nucleus collisions in 10-100 GeV energy range were obtained. 12 refs.; 10 figs

  18. Slowing down of 100 keV antiprotons in Al foils

    Science.gov (United States)

    Nordlund, K.

    2018-03-01

    Using energy degrading foils to slow down antiprotons is of interest for producing antihydrogen atoms. I consider here the slowing down of 100 keV antiprotons, that will be produced in the ELENA storage ring under construction at CERN, to energies below 10 keV. At these low energies, they are suitable for efficient antihydrogen production. I simulate the antihydrogen motion and slowing down in Al foils using a recently developed molecular dynamics approach. The results show that the optimal Al foil thickness for slowing down the antiprotons to below 5 keV is 910 nm, and to below 10 keV is 840 nm. Also the lateral spreading of the transmitted antiprotons is reported and the uncertainties discussed.

  19. Experimental and computational study of the injection of antiprotons into a positron plasma for antihydrogen production

    Energy Technology Data Exchange (ETDEWEB)

    Amole, C.; Capra, A.; Menary, S. [Department of Physics and Astronomy, York University, Toronto, M3J 1P3 Ontario (Canada); Ashkezari, M. D.; Hayden, M. E. [Department of Physics, Simon Fraser University, Burnaby, V5A 1S6 British Columbia (Canada); Baquero-Ruiz, M.; Little, A.; So, C.; Zhmoginov, A. [Department of Physics, University of California, Berkeley, California 94720 (United States); Bertsche, W. [Department of Physics, College of Science, Swansea University, SA2 8PP Swansea (United Kingdom); School of Physics and Astronomy, University of Manchester, M13 9PL Manchester (United Kingdom); Daresbury Laboratory, Cockcroft Institute, WA4 4AD Warrington (United Kingdom); Butler, E. [Physics Department, CERN, CH-1211 Geneva 23 (Switzerland); Cesar, C. L.; Silveira, D. M. [Instituto de Fisica, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941 (Brazil); Charlton, M.; Deller, A.; Eriksson, S.; Isaac, C. A.; Madsen, N.; Napoli, S. C.; Shields, C. R. [Department of Physics, College of Science, Swansea University, SA2 8PP Swansea (United Kingdom); Collaboration: ALPHA Collaboration; and others

    2013-04-15

    One of the goals of synthesizing and trapping antihydrogen is to study the validity of charge-parity-time symmetry through precision spectroscopy on the anti-atoms, but the trapping yield achieved in recent experiments must be significantly improved before this can be realized. Antihydrogen atoms are commonly produced by mixing antiprotons and positrons stored in a nested Penning-Malmberg trap, which was achieved in ALPHA by an autoresonant excitation of the antiprotons, injecting them into the positron plasma. In this work, a hybrid numerical model is developed to simulate antiproton and positron dynamics during the mixing process. The simulation is benchmarked against other numerical and analytic models, as well as experimental measurements. The autoresonant injection scheme and an alternative scheme are compared numerically over a range of plasma parameters which can be reached in current and upcoming antihydrogen experiments, and the latter scheme is seen to offer significant improvement in trapping yield as the number of available antiprotons increases.

  20. Extra Low Energy Antiproton ring ELENA : from the conception to the implementation phase

    CERN Document Server

    Bartmann, W; Breuker, H; Butin, F; Carli, C; Eriksson, T; Maury, S; Pasinelli, S; Tranquille, G; Oelert, W

    2014-01-01

    The Extra Low Energy Antiproton ring (ELENA) is a CERN project aiming at constructing a small 30 m circumference synchrotron to further decelerate antiprotons from the Antiproton Decelerator AD from 5.3 MeV to 100 keV. Controlled deceleration in a synchrotron equipped with an electron cooler to reduce emittances in all three planes will allow the existing AD experiments to increase substantially their antiproton capture efficiencies and render new experiments possible. The ELENA design is now well advanced and the project is moving to the implementation phase. Component design and construction are taking place at present for installation foreseen during the second half of 2015 and beginning of 2016 followed by ring commissioning until the end of 2016. New electrostatic transfer lines to the experiments will be installed and commissioned during the first half of 2017 followed by the first physics operation with ELENA. Basic limitations like Intra Beam Scattering limiting the emittances obtained under electron ...

  1. Experimental and computational study of the injection of antiprotons into a positron plasma for antihydrogen production

    International Nuclear Information System (INIS)

    Amole, C.; Capra, A.; Menary, S.; Ashkezari, M. D.; Hayden, M. E.; Baquero-Ruiz, M.; Little, A.; So, C.; Zhmoginov, A.; Bertsche, W.; Butler, E.; Cesar, C. L.; Silveira, D. M.; Charlton, M.; Deller, A.; Eriksson, S.; Isaac, C. A.; Madsen, N.; Napoli, S. C.; Shields, C. R.

    2013-01-01

    One of the goals of synthesizing and trapping antihydrogen is to study the validity of charge–parity–time symmetry through precision spectroscopy on the anti-atoms, but the trapping yield achieved in recent experiments must be significantly improved before this can be realized. Antihydrogen atoms are commonly produced by mixing antiprotons and positrons stored in a nested Penning-Malmberg trap, which was achieved in ALPHA by an autoresonant excitation of the antiprotons, injecting them into the positron plasma. In this work, a hybrid numerical model is developed to simulate antiproton and positron dynamics during the mixing process. The simulation is benchmarked against other numerical and analytic models, as well as experimental measurements. The autoresonant injection scheme and an alternative scheme are compared numerically over a range of plasma parameters which can be reached in current and upcoming antihydrogen experiments, and the latter scheme is seen to offer significant improvement in trapping yield as the number of available antiprotons increases.

  2. High-precision spectroscopy of antiprotonic helium-first results from the AD of CERN

    CERN Document Server

    Widmann, E

    2001-01-01

    New results of the laser and microwave spectroscopy of antiprotonic helium "atomcules" obtained in the first year of operation of the Antiproton Decelerator (AD) facility of CERN are presented. They include the discovery of three new resonant transitions and the determination of the zero-density wavelength of six transitions with an accuracy of 130 ppb in the best case. Auger rates of those states were also determined, and two of them were found to be several orders of magnitude larger than expected from a simple estimate based on the multipolarity Delta l, i.e., the jump in angular momentum required for the antiproton to reach the next lower-lying state of ionized pHe /sup ++/. Furthermore, a first signal of a two-laser microwave triple resonance to measure the hyperfine splitting in antiprotonic helium was observed. (39 refs).

  3. Comprehensive Study for an Optimized Redesign of the CERN's Antiproton Decelerator Target

    CERN Document Server

    AUTHOR|(CDS)2089345; Perillo-Marcone, Antonio; Muñoz-Cobo, Jose-Luis

    2018-04-16

    The Antiproton Decelerator Target (AD-Target) is a unique device responsible for the production of antiprotons at the European Organization for Nuclear Research (CERN). During operation, intense 26 GeV energy proton beams are impacted into its core, made of a 3 mm diameter rod of a high density material such as iridium, creating secondary particles -including antiprotons- from the nuclear reactions induced in its interior. This thesis delves into the characteristics of antiproton production and in particular in the mechanical response of the target core material, which is exposed to a rise of temperature of approximate 2000 degrees Celsius in less than 0.5 microseconds each time is impacted by the primary proton beam. A coupled numerical-experimental approach has been applied for this purpose. Specific computational tools, called hydrocodes, have been used for simulating the extreme dynamic response taking place in the target core and its containing graphite matrix, indicating their potential damage and frag...

  4. Symposium on Highlights from 14 years of LEAR Physics : "Antiproton Mass" by G. Gabrielse

    CERN Multimedia

    1998-01-01

    Symposium on Highlights from 14 years Physics hold at CERN, commemorating the closure of LEAR and giving a topical review of the impact of experiments with low energy antiprotons in their respective fields

  5. Symposium on Highlights from 14 years of LEAR Physics: "Light Antiprotonic Atoms" by R. Hayano

    CERN Multimedia

    1998-01-01

    Symposium on Highlights from 14 years of LEAR Physics hold at CERN, commemorating the closure of LEAR and giving a topical review of the impact of experiments with low energy antiprotons in their respective fields

  6. On the Utility of Antiprotons as Drivers for Inertial Confinement Fusion

    International Nuclear Information System (INIS)

    Perkins, L J; Orth, C D; Tabak, M

    2003-01-01

    By contrast to the large mass, complexity and recirculating power of conventional drivers for inertial confinement fusion (ICF), antiproton annihilation offers a specific energy of 90MJ/(micro)g and thus a unique form of energy packaging and delivery. In principle, antiproton drivers could provide a profound reduction in system mass for advanced space propulsion by ICF. We examine the physics underlying the use of antiprotons ((bar p)) to drive various classes of high-yield ICF targets by the methods of volumetric ignition, hotspot ignition and fast ignition. The useable fraction of annihilation deposition energy is determined for both (bar p)-driven ablative compression and (bar p)-driven fast ignition, in association with 0-D and 1-D target burn models. Thereby, we deduce scaling laws for the number of injected antiprotons required per capsule, together with timing and focal spot requirements. The kinetic energy of the injected antiproton beam required to penetrate to the desired annihilation point is always small relative to the deposited annihilation energy. We show that heavy metal seeding of the fuel and/or ablator is required to optimize local deposition of annihilation energy and determine that a minimum of ∼3x10 15 injected antiprotons will be required to achieve high yield (several hundred megajoules) in any target configuration. Target gains - i.e., fusion yields divided by the available p - (bar p) annihilation energy from the injected antiprotons (1.88GeV/(bar p)) - range from ∼3 for volumetric ignition targets to ∼600 for fast ignition targets. Antiproton-driven ICF is a speculative concept, and the handling of antiprotons and their required injection precision - temporally and spatially - will present significant technical challenges. The storage and manipulation of low-energy antiprotons, particularly in the form of antihydrogen, is a science in its infancy and a large scale-up of antiproton production over present supply methods would be

  7. On the utility of antiprotons as drivers for inertial confinement fusion

    International Nuclear Information System (INIS)

    Perkins, L. John; Orth, Charles D.; Tabak, Max

    2004-01-01

    In contrast to the large mass, complexity and recirculating power of conventional drivers for inertial confinement fusion (ICF), antiproton annihilation offers a specific energy of 90 MJ μg -1 and thus a unique form of energy packaging and delivery. In principle, antiproton drivers could provide a profound reduction in system mass for advanced space propulsion by ICF. We examine the physics underlying the use of antiprotons (p-bar) to drive various classes of high-yield ICF targets by the methods of volumetric ignition, hotspot ignition and fast ignition. The useable fraction of annihilation deposition energy is determined for both p-bar-driven ablative compression and p-bar-driven fast ignition, in association with zero- and one-dimensional target burn models. Thereby, we deduce scaling laws for the number of injected antiprotons required per capsule, together with timing and focal spot requirements. The kinetic energy of the injected antiproton beam required to penetrate to the desired annihilation point is always small relative to the deposited annihilation energy. We show that heavy metal seeding of the fuel and/or ablator is required to optimize local deposition of annihilation energy and determine that a minimum of ∼3 x 10 15 injected antiprotons will be required to achieve high yield (several hundred megajoules) in any target configuration. Target gains-i.e. fusion yields divided by the available p-p-bar annihilation energy from the injected antiprotons (1.88 GeV/p-bar)-range from ∼3 for volumetric ignition targets to ∼600 for fast ignition targets. Antiproton-driven ICF is a speculative concept, and the handling of antiprotons and their required injection precision - temporally and spatially - will present significant technical challenges. The storage and manipulation of low-energy antiprotons, particularly in the form of antihydrogen, is a science in its infancy and a large scale-up of antiproton production over present supply methods would be

  8. On the Utility of Antiprotons as Drivers for Inertial Confinement Fusion

    Energy Technology Data Exchange (ETDEWEB)

    Perkins, L J; Orth, C D; Tabak, M

    2003-10-20

    By contrast to the large mass, complexity and recirculating power of conventional drivers for inertial confinement fusion (ICF), antiproton annihilation offers a specific energy of 90MJ/{micro}g and thus a unique form of energy packaging and delivery. In principle, antiproton drivers could provide a profound reduction in system mass for advanced space propulsion by ICF. We examine the physics underlying the use of antiprotons ({bar p}) to drive various classes of high-yield ICF targets by the methods of volumetric ignition, hotspot ignition and fast ignition. The useable fraction of annihilation deposition energy is determined for both {bar p}-driven ablative compression and {bar p}-driven fast ignition, in association with 0-D and 1-D target burn models. Thereby, we deduce scaling laws for the number of injected antiprotons required per capsule, together with timing and focal spot requirements. The kinetic energy of the injected antiproton beam required to penetrate to the desired annihilation point is always small relative to the deposited annihilation energy. We show that heavy metal seeding of the fuel and/or ablator is required to optimize local deposition of annihilation energy and determine that a minimum of {approx}3x10{sup 15} injected antiprotons will be required to achieve high yield (several hundred megajoules) in any target configuration. Target gains - i.e., fusion yields divided by the available p - {bar p} annihilation energy from the injected antiprotons (1.88GeV/{bar p}) - range from {approx}3 for volumetric ignition targets to {approx}600 for fast ignition targets. Antiproton-driven ICF is a speculative concept, and the handling of antiprotons and their required injection precision - temporally and spatially - will present significant technical challenges. The storage and manipulation of low-energy antiprotons, particularly in the form of antihydrogen, is a science in its infancy and a large scale-up of antiproton production over present supply

  9. Study of X-Ray and $\\gamma$-Ray Spectra from Antiprotonic Atoms at the Slowly Extracted Antiproton Beam of LEAR

    CERN Multimedia

    2002-01-01

    This experiment will study the X-ray spectra of antiprotonic atoms and the $\\gamma$ spectra of residual nuclei after the antiproton absorption. We intend to begin with measurements on selected isotopically pure targets. Strong interaction effects, the antiproton absorption and the atomic cascade are analysed through the measurement of energies, lineshapes, relative and absolute intensities of all observable lines. The experiments are continued to determine st in resolved fine structure levels and in different isotopes of the same element. Coincidence techniques may be applied. All components of the experimental set-up are already existing from previous experiments and we could begin the measurements with any slowly extracted beam of low energy at LEAR.

  10. Problems in the phenomenological analysis of cross-section difference sigmasub(pp)-sigmasub(pn) and sigmasub(antiproton proton)-sigmasub(antiproton neutron)

    International Nuclear Information System (INIS)

    Bouquet, A.; Diu, B.; Leader, E.; Nicolescu, B.

    1976-01-01

    It is shown that uncertainties in the exact value of the Glauber correction make it virtually impossible to deduce any significant conclusions about the asymptotic behaviour of the sigmasub(pp)-sigmasub(pn) and sigma sub(antiproton proton)-sigmasub(antiproton neutron) cross-section differences, if only data on pp, pd, antiproton proton and antiprotond collisions are used. Nevertheless it can be demonstrated that the imaginary part of the rho exchange amplitude is basically Regge behaved. If, on the other hand, neutron beam data on sigmasub(np) are used, it can be shown that the imaginary part of the A 2 exchange amplitude contains a non-Regge, growing, asymptotic component, reminiscent of that found in the I=) symmetric amplitude

  11. Measurement of the antiproton-nucleus annihilation cross-section at low energy

    Science.gov (United States)

    Aghai-Khozani, H.; Bianconi, A.; Corradini, M.; Hayano, R.; Hori, M.; Leali, M.; Lodi Rizzini, E.; Mascagna, V.; Murakami, Y.; Prest, M.; Vallazza, E.; Venturelli, L.; Yamada, H.

    2018-02-01

    Systematic measurements of the annihilation cross sections of low energy antinucleons were performed at CERN in the 80's and 90's. However the antiproton data on medium-heavy and heavy nuclear targets are scarce. The ASACUSA Collaboration at CERN has measured the antiproton annihilation cross section on carbon at 5.3 MeV: the value is (1.73 ± 0.25) barn. The result is compared with the antineutron experimental data and with the theoretical previsions.

  12. Antiproton production in nucleon-nucleus and nucleus-nucleus collisions at the CERN-SPS

    International Nuclear Information System (INIS)

    Kadija, K.; Schmitz, N.; Seyboth, P.

    1996-01-01

    A model for antiproton production in nucleon-nucleus and nucleus-nucleus collisions at 200 GeV per nucleon, based on the wounded nucleon model is developed. The predictions are compared to published nucleon-nucleus and sulphur-nucleus data. The results suggest the presence of similar antiproton production processes in nucleon-nucleus and nucleus-nucleus collisions near midrapidity. (orig.)

  13. Primary populations of metastable antiprotonic $^{4}He$ and $^{3}He$ atoms

    CERN Document Server

    Hori, Masaki; Hayano, R S; Ishikawa, T; Sakuguchi, J; Tasaki, T; Widmann, E; Yamaguchi, H; Torii, H A; Juhász, B; Horváth, D; Yamazaki, T

    2002-01-01

    Initial population distributions of metastable antiprotonic **4He and **3He atoms over principal and angular momentum quantum numbers were investigated using laser spectroscopy. The total fractions of antiprotons captured into the metastable states of the atoms were deduced. Cascade calculations were performed using the measure populations to reproduce the delayed annihilation time spectrum. Results showed agreement between the simulated and measured spectra. (Edited abstract) 30 Refs.

  14. Antiproton, positron, and electron imaging with a microchannel plate/phosphor detector

    CERN Document Server

    Andresen, G B; Bowe, P D; Bray, C; Butler, E; Cesar, C L; Chapman, S; Charlton, M; Fajans, J; Fujiwara, M C; Gill, D R; Hangst, J S; Hardy, W N; Hayano, R S; Hayden, M E; Humphries, A J; Hydomako, R; Jørgensen, L V; Kerrigan, S J; Kurchaninov, L; Lambo, R; Madsen, N; Nolan, P; Olchanski, K; Olin, A; Povilus, A; Pusa, P; Sarid, E; Seif El Nasr, S; Silveira, D M; Storey, J W; Thompson, R I; van der Werf, D P; Yamazaki, Y

    2009-01-01

    A microchannel plate (MCP)/phosphor screen assembly has been used to destructively measure the radial profile of cold, confined antiprotons, electrons, and positrons in the ALPHA experiment, with the goal of using these trapped particles for antihydrogen creation and confinement. The response of the MCP to low energy (10-200 eV, <1 eV spread) antiproton extractions is compared to that of electrons and positrons.

  15. Examination of X-ray spectra from the antiprotonic helium isotopes 3He and 4He

    International Nuclear Information System (INIS)

    Schneider, M.

    1987-05-01

    Using the high intensity antiprotonic LEAR beam at CERN (Geneva), several measurements were done to investigate the X-ray spectra of the antiprotonic Helium isotopes 3 He and 4 He. For the first time antiprotons were stopped in gases at low pressures (600, 375, 72 and 36 mbar), which permitted observations on nearly isolated atoms. A newly developed method for stopping the antiprotons in gases by means of a focusing cyclotron field surrounding the target gas was used. The field was supplied by a superconducting magnet ('cyclotron trap'). The antiprotons were tangentially injected into the cyclotron field, where they slowed down by ionising the target gas. The inhomogeneous magnetic field guided the antiprotons in spiral orbits to the magnetic center. Thus, even at low pressures a very small stopping volume could be achieved. To detect the X-rays different Si(Li)- and Ge-semiconductor detectors were used, some of which were furnished with 'guard-rings'. They were used to investigate the effects of the strong interaction between the antiproton and the nucleus in the (3d → 2p) transition in both isotopes. The analyzis of this transition permitted directly the determination of the shift and width of the 2p-level. The width of the 3d-level could be determined only indirectly using an intensity balance. The utilization of gases with different pressures permitted investigations of the pressure dependence of the antiprotonic deexcitation process. The results for the widths and shifts were compared with earlier measurements and theoretical predictions. The theory agrees only partly with the measurements. The evaluation of a complex scattering length using an optical model contradicts some of the results of calculations. (orig.) [de

  16. Interaction of antiprotons with Rb atoms and a comparison of antiproton stopping powers of the atoms H, Li, Na, K, and Rb

    DEFF Research Database (Denmark)

    Lühr, Armin Christian; Fischer, Nicolas; Saenz, Alejandro

    2009-01-01

    Ionization and excitation cross sections as well as electron-energy spectra and stopping powers of the alkali metal atoms Li, Na, K, and Rb colliding with antiprotons were calculated using a time-dependent channel-coupling approach. An impact-energy range from 0.25 to 4000 keV was considered....... The target atoms are treated as effective one-electron systems using a model potential. The results are compared with calculated cross sections for antiproton-hydrogen atom collisions....

  17. TH-C-12A-02: Comparison of Two RapidArc Delivery Strategies in Stereotactic Body Radiotherapy of Stage I and II Peripheral Lung Tumors with Unflattened Beams

    International Nuclear Information System (INIS)

    Huang, B; Lu, J; Chen, J; Chen, C; Lin, P; Kuang, Y

    2014-01-01

    Purpose: The full arcs strategy used in SBRT with RapidArc and unflattened (FFF) beams in large and heterogeneous peripheral non-smallcell lung cancer (NSCLC) appears to be suboptimal as it increases the disadvantageous dose to the contralateral lung, which potentially increases the toxicity to surrounding tissues. In this study, we investigated, for the first time, the dose delivery strategies using partial arcs (PA) and the fully rotational arcs with avoidance sectors (FAAS) for SBRT with FFF beams in peripheral NSCLC patients. Methods: Eighteen patients with NSCLC (stage I and II) were selected for this study. Nine patients with a GTV <= 10cc were designated as the small tumor group. The remaining nine patients with a GTV between 10 cc and 44 cc were assigned to the large tumor group. The treatment plans were generated in eighteen patients using PA and FAAS, respectively, and delivered with a Varian TrueBeam Linac. Dosimetry of the target and organs at risk (OAR), total MU, out-of-field dose, and delivery time were analyzed. Delta4 and Portal dosimetry were employed to evaluate the delivery accuracy. Results: or the small tumor group, the FAAS plans significantly achieved a better conformity index, the lower total MU and out-of-field dose, a shorter treatment time, and the reduced doses to cord, heart, and lung (p < 0.05). But the target doses were slightly higher than that delivered by PA plans. For the large tumor group, the PA plans significantly attained a better conformity index and a shorter treatment time (p < 0.05). Furthermore, all plans achieved a high pass rate, with all the gamma indices greater than 97% at the Γ 3mm, 3% threshold. Conclusion: This study suggests that FAAS strategy is more beneficial for small tumor patients undergoing lung SBRT with FFF beams. However, for large tumor patients, PA strategy is recommended. NIH/NIGMS grant U54 GM104944, Lincy Endowed Assistant Professorship

  18. Radiotherapy of adult nodal non Hodgkin's lymphoma

    International Nuclear Information System (INIS)

    Gamen, G.; Thirion, P.

    1999-01-01

    The role of radiotherapy in the treatment of nodal non-Hodgkin's lymphoma has been modified by the introduction of efficient chemotherapy and the development of different pathological classifications. The recommended treatment of early-stage aggressive lymphomas is primarily a combination chemotherapy. The interest of adjuvant radiotherapy remains unclear and has to be established through large prospective trials. If radiation therapy has to be delivered, the historical results of exclusive radiation therapy showed that involved-fields and a dose of 35-40 Gy (daily fraction of 1.8 Gy, 5 days a week) are the optimal schedule. The interest of radiotherapy in the treatment of advanced-stage aggressive lymphoma is yet to be proven. Further studies had to stratify localized stages according to the factors of the International Prognostic Index. For easy-stage low-grade lymphoma, radiotherapy remains the standard treatment. However, the appropriate technique to use is controversial. Involved-field irradiation at a dose of 35 Gy seems to be the optimal schedule, providing a 10 year disease-free survival rate of 50 % and no major toxicity. There is no standard indication of radiotherapy in the treatment advanced-stage low-grade lymphoma. For 'new' nodal lymphoma's types, the indication of radiotherapy cannot be established (mantle-zone lymphoma, marginal zone B-cell lymphoma) or must take into account the natural history (Burkitt's lymphoma, peripheral T-cell lymphoma) and the sensibility to others therapeutic methods. (authors)

  19. Centrality and collision system dependence of antiproton production from p+A to Au+Au collisions at AGS energies

    International Nuclear Information System (INIS)

    Sako, H.; Ahle, L.; Akiba, Y.

    1997-12-01

    Antiproton production in heavy ion collisions reflects subtle interplay between initial production and absorption by nucleons. Because the AGS energies (10--20 A·GeV/c) are close to the antiproton production threshold, antiproton may be sensitive to cooperative processes such as QGP and hadronic multi-step processes. On the other hand, antiproton has been proposed as a probe of baryon density due to large N anti N annihilation cross sections. Cascade models predict the maximum baryon density reaches about 10 times the normal nucleus density in central Au+Au collisions, where the strong antiproton absorption is expected. In this paper, the authors show systematic studies of antiproton production from p+A to Au+Au collisions

  20. Radiotherapy in bladder cancer

    International Nuclear Information System (INIS)

    Rozan, R.

    1992-01-01

    In 1992, the problem of the vesical radiotherapy is not resolved. The author presents the situation and the different techniques of radiotherapy in bladder cancers: external radiotherapy, only and associated with surgery, interstitial curietherapy and non-classical techniques as per operative radiotherapy, neutron therapy and concurrent radiotherapy with chemotherapy. In order to compare their efficiency, the five-year survival are given in all cases.(10 tabs)

  1. Production of light elements by cascades from energetic antiprotons in the early Universe and problem of nuclear cosmoarcheology

    International Nuclear Information System (INIS)

    Levitan, Yu.L.; Sobol', I.M.; Khlopov, M.Yu.; Chechetkin, V.M.

    1988-01-01

    The mathematical model of the process of light-element (D and 3 He) production due to disintegration of 4 He nuclei, induced by nonequilibrium processes of production of energetic antiprotons in the early Universe is suggested. Numerical calculations show that formation of the nucleon cascade induced by antiproton slowing down increases the D and 3 He yield due to the growth of probability of disintegration of several 4 He nuclei by a single antiproton and due to disintegration of such nuclei by cascade protons. Restraints on the concentration of possible sources of energetic antiprotons in the early Universe are strengthened respectively

  2. On the determination of the energy of antiprotonic X-rays by critical absorption and the theoretical discussion of results

    International Nuclear Information System (INIS)

    Joedicke, B.

    1985-06-01

    This work examines the possibility of measuring the energies of antiprotonic X-rays by critical absorption. Scanning the periodic table many isotopes are found where the energy of an antiprotonic X-ray coincides with a K-absorption-edge of a chemical element. Those candidates where the energy can be measured with high accuracy are discussed here. Also a computer program which calculates transition energies of antiprotonic atoms is examined. Necessary additions are listed and the corrections are shown. In combination with this program the candidates are the basis for a precise determination of the mass of the antiproton. (orig.) [de

  3. Enhanced antiproton production in Pb(160 A GeV)+Pb reactions evidence for quark gluon matter?

    CERN Document Server

    Bleicher, M; Bass, S A; Soff, S; Stöcker, H

    2000-01-01

    The centrality dependence of the antiproton per participant ratio is studied in Pb(160 AGeV)+Pb reactions. Antiproton production in collisions of heavy nuclei at the CERN/SPS seems considerably enhanced as compared to conventional hadronic physics, given by the antiproton production rates in $pp$ and antiproton annihilation in $\\bar{p}p$ reactions. This enhancement is consistent with the observation of strong in-medium effects in other hadronic observables and may be an indication of partial restoration of chiral symmetry.

  4. Radiotherapy of bronchogenic carcinoma

    International Nuclear Information System (INIS)

    Heilmann, H.P.

    1982-01-01

    Radiotherapy of branchogenic carcinoma comprises; palliative treatment, postoperative or pre-operative radiotherapy, radiotherapy as part of a combination of chemotherapy and radiotherapy of small cell carcinoma and curative radiotherapy of non-operable non-small cell carcinoma. Atelectasis and obstruction are indications for palliative radiotherapy. Postoperative radiotherapy is given only in cases of incomplete resection or mediastinal metastases. In the treatment of small cell carcinoma by combined irradiation and chemotherapy the mediastinum and primary tumour are irradiated, generally after chemotherapy, and the C.N.S. receives prophylactic radiotherapy. Curative radiotherapy is indicated in cases of non-operable small cell carcinoma. Irradiation with doses of 60-70 Gy produced 5-years-survival rates of 10-14% in cases classified as T 1 -T 2 N 0 M 0 . (orig.) [de

  5. Constraining pre big-bang-nucleosynthesis expansion using cosmic antiprotons

    International Nuclear Information System (INIS)

    Schelke, M.; Catena, R.; Fornengo, N.; Masiero, A.; Pietroni, M.

    2006-06-01

    A host of dark energy models and non-standard cosmologies predict an enhanced Hubble rate in the early Universe: perfectly viable models, which satisfy Big Bang Nucleosynthesis (BBN), cosmic microwave background and general relativity tests, may nevertheless lead to enhancements of the Hubble rate up to many orders of magnitude. In this paper we show that strong bounds on the pre-BBN evolution of the Universe may be derived, under the assumption that dark matter is a thermal relic, by combining the dark matter relic density bound with constraints coming from the production of cosmic-ray antiprotons by dark matter annihilation in the Galaxy. The limits we derive can be sizable and apply to the Hubble rate around the temperature of dark matter decoupling. For dark matter masses lighter than 100 GeV, the bound on the Hubble-rate enhancement ranges from a factor of a few to a factor of 30, depending on the actual cosmological model, while for a mass of 500 GeV the bound falls in the range 50-500. Uncertainties in the derivation of the bounds and situations where the bounds become looser are discussed. We finally discuss how these limits apply to some specific realizations of non-standard cosmologies: a scalar-tensor gravity model, kination models and a Randall-Sundrum D-brane model. (Orig.)

  6. Constraining pre big-bang-nucleosynthesis expansion using cosmic antiprotons

    Energy Technology Data Exchange (ETDEWEB)

    Schelke, M. [Istituto Nazionale di Fisica Nucleare, Torino (Italy); Catena, R. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Fornengo, N. [Torino Univ. (Italy). Dipt. di Fisica Teorica]|[Istituto Nazionale di Fisica Nucleare, Torino (Italy); Masiero, A. [Pavoa Univ. (Italy). Dipt. di Fisica]|[Istituto Nazionale di Fisica Nucleare, Padova (Italy); Pietroni, M. [Istituto Nazionale di Fisica Nucleare, Padova (Italy)

    2006-06-15

    A host of dark energy models and non-standard cosmologies predict an enhanced Hubble rate in the early Universe: perfectly viable models, which satisfy Big Bang Nucleosynthesis (BBN), cosmic microwave background and general relativity tests, may nevertheless lead to enhancements of the Hubble rate up to many orders of magnitude. In this paper we show that strong bounds on the pre-BBN evolution of the Universe may be derived, under the assumption that dark matter is a thermal relic, by combining the dark matter relic density bound with constraints coming from the production of cosmic-ray antiprotons by dark matter annihilation in the Galaxy. The limits we derive can be sizable and apply to the Hubble rate around the temperature of dark matter decoupling. For dark matter masses lighter than 100 GeV, the bound on the Hubble-rate enhancement ranges from a factor of a few to a factor of 30, depending on the actual cosmological model, while for a mass of 500 GeV the bound falls in the range 50-500. Uncertainties in the derivation of the bounds and situations where the bounds become looser are discussed. We finally discuss how these limits apply to some specific realizations of non-standard cosmologies: a scalar-tensor gravity model, kination models and a Randall-Sundrum D-brane model. (Orig.)

  7. The magnetic moments of the proton and the antiproton

    CERN Document Server

    Ulmer, S.; Blaum, K.; Braeuninger, S.; Franke, K.; Kracke, H.; Leiteritz, C.; Matsuda, Y.; Nagahama, H.; Ospelkaus, C.; Rodegheri, C.C.; Quint, W.; Schneider, G.; Smorra, C.; Van Gorp, S.; Walz, J.; Yamazaki, Y.

    2014-01-01

    Recent exciting progress in the preparation and manipulation of the motional quantum states of a single trapped proton enabled the first direct detection of the particle's spin state. Based on this success the proton magnetic moment $\\mu_p$ was measured with ppm precision in a Penning trap with a superimposed magnetic field inhomogeneity. An improvement by an additional factor of 1000 in precision is possible by application of the so-called double Penning trap technique. In a recent paper we reported the first demonstration of this method with a single trapped proton, which is a major step towards the first direct high-precision measurement of $\\mu_p$. The techniques required for the proton can be directly applied to measure the antiproton magnetic moment $\\mu_{\\bar{p}}$. An improvement in precision of $\\mu_{\\bar{p}}$ by more than three orders of magnitude becomes possible, which will provide one of the most sensitive tests of CPT invariance. To achieve this research goal we are currently setting up the Baryo...

  8. Multilepton production in neutrino interactions and proton-antiproton collisions

    International Nuclear Information System (INIS)

    Valenzuela, G.N.

    1985-01-01

    In part I, we consider the class of events containing 2 or 3 leptons in (anti-neutrino deep inelastic scattering and in proton-antiproton collisions. Understanding the characteristics and rate of production of this type of event has often proven to be a theoretical challenge. We show that a cluster model involving associated-charm production not only accounts for certain dimuon events, but also affords better agreement with experiment regarding trimuons produced in neutrino interactions. We also investigate correlations between D-meson and dimuon production in p anti p collisions in the context of a cluster model which includes the possibility of finding b anti b pairs in jets. Part II consists of a study of radiation zeros in the reaction p anti p → l anti nuγX. It has been proposed that the radiation zero phenomenon could be observed in processes involving the radiative decay of the W-boson. These processes might allow the measurement of the W anomalous magnetic moment. We calculate the effect on this measurement of the decay width and the non-zero transverse momentum of the W. We find that although the radiation zero is filled in to some extent, it might still be possible to estimate the magnetic moment of the W in future experiments

  9. Studying the potential of antihyperons in nuclei with antiprotons

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez Lorente, Alicia; Bleser, Sebastian; Steinen, Marcell [Helmholtz-Institut Mainz (Germany); Pochodzalla, Josef [Institute for nuclear physics, JGU Mainz (Germany); Collaboration: PANDA-Collaboration

    2014-07-01

    The interaction between an antibaryon and a nucleus may shed light on the short range antibaryon-baryon force in a unique way. However, because of the deep imaginary part of the nuclear potential of antibaryons, the physics of antihyperons in nuclei is hitherto an uncharted territory. Recently it was proposed to use transverse momentum correlations of exclusively produced antihyperon-hyperon pairs in antiproton-nucleus collisions to obtain information on the antihyperon potentials relative to that of the corresponding hyperon. In the present study we use the Giessen Boltzmann-Uehling- Uhlenbeck Transportmodell (GiBUU) to explore the production of exclusive hyperon-antihyperon pairs close to threshold. Unlike the schematic calculation, these GiBBU simulations take e.g. important rescattering effects into account. In case of anti p + {sup 20}Ne → anti ΛΛ+X we confirm a significant sensitivity of transverse momentum correlations to the nuclear potential of Λs. We also explore the feasibility of such measurements at the PANDA experiment of the international facility FAIR.

  10. SU-E-T-322: Dosimetric Evaluation of Rib Dose in Peripheral Lung Tumors Treated with X-Ray Voxel Monte Carlo (XVMC) Based Lung Stereotactic Body Radiotherapy (SBRT) Following RTOG 0915 Guidelines

    Energy Technology Data Exchange (ETDEWEB)

    Pokhrel, D; Sood, S; Badkul, R; Jiang, H; Kumar, P; Wang, F [University of Kansas Hospital, Kansas City, KS (United States)

    2015-06-15

    Purpose: To evaluate XVMC computed rib doses for peripherally located non-small-cell-lung tumors treated with SBRT following RTOG-0915 guidelines. Methods: Twenty patients with solitary peripherally located non-small-cell-lung tumors were treated using XVMC-based SBRT to 50–54Gy in 5−3 fractions, respectively, for PTV(V100%)=95%. Based on 4D-CT, ITV was delineated on MaximumIP images and organs-at-risk(OARs) including ribs were contoured on MeanIP images. Mean PTV(ITV+5mm uniform margin) was 46.1±38.7cc (range, 11.1–163.0cc). XVMC SBRT treatment plans were generated with a combination of non-coplanar 3D-conformal arcs/beams, and were delivered by Novalis-TX consisting of HD-MLCs and a 6MV-SRS(1000MU/min) beam, following RTOG-0915 criteria. XVMC rib maximum dose and dose to <1cc, <5cc, <10cc were evaluated as a function of PTV, prescription dose and 3D-distance from tumor isocenter to the most proximal rib contour. Plans were re-computed using heterogeneity-corrected pencil-beam (PB-hete) algorithm utilizing identical beam geometry/MLC positions and MUs and subsequently compared to XVMC. Results: XVMC average maximum rib dose was 50.9±6.4Gy (range, 35.1–59.3Gy). XVMC mean rib dose to <1cc was 41.6±5.6Gy (range, 27.9–47.9Gy), <5cc was 31.2±7.3Gy (range, 10.6–43.1Gy), and <10cc was 21.2±8.7Gy (range, 1.1–36Gy), respectively. For the given prescription, correlation between PTV and rib doses to <5cc (p=0.005) and <10cc (p=0.018) was observed. 3D-distance from the tumor isocenter to the proximal rib contour strongly correlated with maximum rib dose (p=0.0001). PB-hete algorithm overestimated maximum rib dose and dose to <1cc, <5cc, and <10cc of ribs by 5%, 3%, 3%, and 3%, respectively. Conclusion: PB-hete overestimates ribs dose relative to XVMC. Since all the clinical XVMC plans were generated without compromising the target coverage (per RTOG-0915), almost all patient’s ribs doses were higher than the protocol guidelines. As expected, larger tumor

  11. SU-E-T-322: Dosimetric Evaluation of Rib Dose in Peripheral Lung Tumors Treated with X-Ray Voxel Monte Carlo (XVMC) Based Lung Stereotactic Body Radiotherapy (SBRT) Following RTOG 0915 Guidelines

    International Nuclear Information System (INIS)

    Pokhrel, D; Sood, S; Badkul, R; Jiang, H; Kumar, P; Wang, F

    2015-01-01

    Purpose: To evaluate XVMC computed rib doses for peripherally located non-small-cell-lung tumors treated with SBRT following RTOG-0915 guidelines. Methods: Twenty patients with solitary peripherally located non-small-cell-lung tumors were treated using XVMC-based SBRT to 50–54Gy in 5−3 fractions, respectively, for PTV(V100%)=95%. Based on 4D-CT, ITV was delineated on MaximumIP images and organs-at-risk(OARs) including ribs were contoured on MeanIP images. Mean PTV(ITV+5mm uniform margin) was 46.1±38.7cc (range, 11.1–163.0cc). XVMC SBRT treatment plans were generated with a combination of non-coplanar 3D-conformal arcs/beams, and were delivered by Novalis-TX consisting of HD-MLCs and a 6MV-SRS(1000MU/min) beam, following RTOG-0915 criteria. XVMC rib maximum dose and dose to <1cc, <5cc, <10cc were evaluated as a function of PTV, prescription dose and 3D-distance from tumor isocenter to the most proximal rib contour. Plans were re-computed using heterogeneity-corrected pencil-beam (PB-hete) algorithm utilizing identical beam geometry/MLC positions and MUs and subsequently compared to XVMC. Results: XVMC average maximum rib dose was 50.9±6.4Gy (range, 35.1–59.3Gy). XVMC mean rib dose to <1cc was 41.6±5.6Gy (range, 27.9–47.9Gy), <5cc was 31.2±7.3Gy (range, 10.6–43.1Gy), and <10cc was 21.2±8.7Gy (range, 1.1–36Gy), respectively. For the given prescription, correlation between PTV and rib doses to <5cc (p=0.005) and <10cc (p=0.018) was observed. 3D-distance from the tumor isocenter to the proximal rib contour strongly correlated with maximum rib dose (p=0.0001). PB-hete algorithm overestimated maximum rib dose and dose to <1cc, <5cc, and <10cc of ribs by 5%, 3%, 3%, and 3%, respectively. Conclusion: PB-hete overestimates ribs dose relative to XVMC. Since all the clinical XVMC plans were generated without compromising the target coverage (per RTOG-0915), almost all patient’s ribs doses were higher than the protocol guidelines. As expected, larger tumor

  12. Interobserver delineation variation in lung tumour stereotacticbody radiotherapy

    DEFF Research Database (Denmark)

    Persson, G. F.; Nygaard, D. E.; Hollensen, Christian

    2012-01-01

    the interobserver delineation variation for stereotactic body radiotherapy (SBRT) of peripheral lung tumours using a cross-sectional study design. Methods 22 consecutive patients with 26 tumours were included. Positron emission tomography/CT scans were acquired for planning of SBRT. Three oncologists and three......-sectional analysis of delineation variation for peripheral lung tumours referred for SBRT, establishing the evidence that interobserver variation is very small for these tumours....

  13. Evidence for the Stochastic Acceleration of Secondary Antiprotons by Supernova Remnants

    Energy Technology Data Exchange (ETDEWEB)

    Cholis, Ilias [Johns Hopkins U.; Hooper, Dan [Chicago U., KICP; Linden, Tim [Ohio State U.

    2017-01-16

    The antiproton-to-proton ratio in the cosmic-ray spectrum is a sensitive probe of new physics. Using recent measurements of the cosmic-ray antiproton and proton fluxes in the energy range of 1-1000 GeV, we study the contribution to the $\\bar{p}/p$ ratio from secondary antiprotons that are produced and subsequently accelerated within individual supernova remnants. We consider several well-motivated models for cosmic-ray propagation in the interstellar medium and marginalize our results over the uncertainties related to the antiproton production cross section and the time-, charge-, and energy-dependent effects of solar modulation. We find that the increase in the $\\bar{p}/p$ ratio observed at rigidities above $\\sim$ 100 GV cannot be accounted for within the context of conventional cosmic-ray propagation models, but is consistent with scenarios in which cosmic-ray antiprotons are produced and subsequently accelerated by shocks within a given supernova remnant. In light of this, the acceleration of secondary cosmic rays in supernova remnants is predicted to substantially contribute to the cosmic-ray positron spectrum, accounting for a significant fraction of the observed positron excess.

  14. Direct detection of antiprotons with the Timepix3 in a new electrostatic selection beamline

    Energy Technology Data Exchange (ETDEWEB)

    Pacifico, N., E-mail: nicola.pacifico@cern.ch [Institute of Physics and Technology, University of Bergen, Allgaten 55, 5007 Bergen (Norway); Aghion, S. [Politecnico of Milano, Piazza Leonardo da Vinci 32, 20133 Milano (Italy); INFN Milano, via Celoria 16, 20133 Milano (Italy); Alozy, J. [Physics Department, CERN, 1211 Geneva 23 (Switzerland); Amsler, C.; Ariga, A.; Ariga, T. [Laboratory for High Energy Physics, Albert Einstein Center for Fundamental Physics, University of Bern, 3012 Bern (Switzerland); Bonomi, G. [Department of Mechanical and Industrial Engineering, University of Brescia, via Branze 38, 25123 Brescia (Italy); INFN Pavia, via Bassi 6, 27100 Pavia (Italy); Bräunig, P. [Kirchhoff-Institute for Physics, Heidelberg University, Im Neuenheimer Feld 227, 69120 Heidelberg (Germany); Bremer, J. [Physics Department, CERN, 1211 Geneva 23 (Switzerland); Brusa, R.S. [Department of Physics, University of Trento, via Sommarive 14, 38123 Povo, Trento (Italy); TIFPA/INFN Trento, via Sommarive 14, 38123 Povo, Trento (Italy); Cabaret, L. [Laboratory Aimé Cotton, University of Paris-Sud, ENS Cachan, CNRS, University Paris-Saclay, 91405 Orsay Cedex (France); Caccia, M. [INFN Milano, via Celoria 16, 20133 Milano (Italy); Department of Science, University of Insubria, Via Valleggio 11, 22100 Como (Italy); Campbell, M. [Physics Department, CERN, 1211 Geneva 23 (Switzerland); Caravita, R. [Department of Physics, University of Genova, via Dodecaneso 33, 16146 Genova (Italy); INFN Genova, via Dodecaneso 33, 16146 Genova (Italy); Castelli, F. [INFN Milano, via Celoria 16, 20133 Milano (Italy); Department of Physics, University of Milano, via Celoria 16, 20133 Milano (Italy); Cerchiari, G. [Max Planck Institute for Nuclear Physics, Saupfercheckweg 1, 69117 Heidelberg (Germany); Chlouba, K. [Czech Technical University, Prague, Brehov 7, 11519 Prague 1 (Czech Republic); and others

    2016-09-21

    We present here the first results obtained employing the Timepix3 for the detection and tagging of annihilations of low energy antiprotons. The Timepix3 is a recently developed hybrid pixel detector with advanced Time-of-Arrival and Time-over-Threshold capabilities and has the potential of allowing precise kinetic energy measurements of low energy charged particles from their time of flight. The tagging of the characteristic antiproton annihilation signature, already studied by our group, is enabled by the high spatial and energy resolution of this detector. In this study we have used a new, dedicated, energy selection beamline (GRACE). The line is symbiotic to the AEgIS experiment at the CERN Antiproton Decelerator and is dedicated to detector tests and possibly antiproton physics experiments. We show how the high resolution of the Timepix3 on the Time-of-Arrival and Time-over-Threshold information allows for a precise 3D reconstruction of the annihilation prongs. The presented results point at the potential use of the Timepix3 in antimatter-research experiments where a precise and unambiguous tagging of antiproton annihilations is required.

  15. Modeling of the Near-Earth Low-Energy Antiproton Fluxes

    Directory of Open Access Journals (Sweden)

    U. B. Jayanthi

    2011-01-01

    Full Text Available The local interstellar antiproton spectrum is simulated taking into account antineutron decay, (He,p interaction, secondary and tertiary antiproton production, and the solar modulation in the “force field” approximation. Inclusive invariant cross-sections were obtained through a Monte Carlo procedure using the Multistage Dynamical Model code simulating various processes of the particle production. The results of the simulations provided flux values of 4⋅10−3 to 10−2 and 10−2 to 1.7⋅10−2 antiprotons/(2 s sr GeV at energies of 0.2 and 1 GeV, respectively, for the solar maximum and minimum epochs. Simulated flux of the trapped antiprotons in the inner magnetosphere due to galactic cosmic ray (GCR interactions with the atmospheric constituents exceeds the galactic antiproton flux up to several orders. These simulation results considering the assumptions with the attendant limitations are in comprehensive agreement with the experimental data including the PAMELA ones.

  16. National arrangements for radiotherapy

    International Nuclear Information System (INIS)

    2007-01-01

    After a presentation of several letters exchanged between the French health ministry and public agencies in charge of public health or nuclear safety after a radiotherapy accident in Epinal, this report comments the evolution of needs in cancerology care and the place given to radiotherapy. It outlines the technological and organisational evolution of radiotherapy and presents the distribution of radiotherapy equipment, of radio-therapists and other radiotherapy professionals in France. Within the context of radiotherapy accidents which occurred in 2007, it presents the regulatory arrangements which aimed at improving the safety, short term and middle term arrangements which are needed to support and structure radiotherapy practice quality. It stresses the fact that the system will deeply evolve by implementing a radiotherapy vigilance arrangement and a permanent follow-on and adaptation plan based on surveys and the creation of a national committee

  17. Radiotherapy of malignant lymphomas

    Energy Technology Data Exchange (ETDEWEB)

    Kujawska, J [Instytut Onkologii, Krakow (Poland)

    1979-01-01

    The paper discusses current views on the role of radiotherapy in the treatment of patients with malignant lymphomas. Principles of radiotherapy employed in the Institute of Oncology in Cracow in case of patients with malignant lymphomas are also presented.

  18. A silicon multiplicity detector system for an experiment on the interaction of antiprotons with nuclei at BNL

    International Nuclear Information System (INIS)

    Ahmad, S.; Bonner, B.E.; Buchanan, J.A.; Clement, J.M.; Empl, A.; Mutchler, G.S.; Toshkov, S.; Chan, C.S.; Kramer, M.A.; Lindenbaum, S.J.; Hallman, T.J.; Madansky, L.; Peaslee, D.C.

    1991-01-01

    A Large Angle Multiplicity Detector (LAMD) system has been developed and used at the BNL experiment E854: Antiproton Nucleus Interactions. This system performed well with an energetic antiproton beam. Charged particle multiplicity distributions from pbar annihilations were measured. We discuss the design and performance of the LAMD system in this paper. 6 refs., 10 figs

  19. Hyperthermia and radiotherapy

    International Nuclear Information System (INIS)

    Fitspatrick, C.

    1990-01-01

    Hyperthermia and radiotherapy have for long been used to assist in the control of tumours, either as separate entities, or, in a combined treatment scheme. This paper outlines why hyperthermia works, thermal dose and the considerations required in the timing when hyperthermia is combined with radiotherapy. Previously reported results for hyperthermia and radiotherapy used together are also presented. 8 refs., 8 tabs

  20. Study of Anti-Hydrogen and Plasma Physics 4.Observation of Antiproton Beams and Nonneutral Plasmas

    CERN Document Server

    Hori, Masaki; Fujiwara, Makoto; Kuroda, Naofumi

    2004-01-01

    Diagnostics of antiproton beams and nonneutral plasmas are described in this chapter. Parallel plate secondary electron emission detectors are used to non-destructively observe the beam position and intensity without loss. Plastic scintillation tracking detectors are useful in determining the position of annihilations of antiprotons in the trap. Three-dimensional imaging of antiprotons in a Penning trap is discussed. The unique capability of antimatter particle imaging has allowed the observation of the spatial distribution of particle loss in a trap. Radial loss is localized to small spots, strongly breaking the azimuthal symmetry expected for an ideal trap. By observing electrostatic eigen-modes of nonneutral plasmas trapped in the Multi-ring electrode trap, the non-destructive measurement of plasma parameters is performed.

  1. Radiation protection for the antiproton production at the FAIR facility; Strahlenschutz fuer die Antiprotonenproduktion bei FAIR

    Energy Technology Data Exchange (ETDEWEB)

    Conrad, I.; Gostischev, V.; Helmecke, M.; Kissel, R.; Knie, K.; Lang, R.; Zieser, B. [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany); Fehrenbacher, G. [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany); FAIR - Facility for Antiproton and Ion Research in Europe GmbH, Darmstadt (Germany)

    2016-07-01

    FAIR (Facility for Antiproton and Ion Research) is an international accelerator centre, which will be constructed at the site of the GSI Helmholtz Centre for Heavy Ion Research in Darmstadt. Antiprotons are produced in a metal cylinder bombarded with high-energy protons (up to 29 GeV). In addition to antiprotons, this interaction creates other secondary particles such as neutrons, pions, muons and gamma rays. The shielding of this radiation field sets high demands on the building design. Necessary radiation protection measures are based on Monte Carlo simulations of the distribution of the spatial dose rate. Furthermore the activation of components, i.e. the transformation of stable nuclei into radioactive isotopes following irradiation, must be considered. The resulting activities of up to 10{sup 11} Bq require a special concept for the handling and transport of affected elements.

  2. Antiproton-proton annihilation into light neutral meson pairs within an effective meson theory

    Science.gov (United States)

    Wang, Ying; Bystritskiy, Yury M.; Ahmadov, Azad I.; Tomasi-Gustafsson, Egle

    2017-08-01

    Antiproton-proton annihilation into light neutral mesons in the few GeV energy domain is investigated in view of a global description of the existing data and predictions for future work at the Antiproton Annihilation at Darmstadt (PANDA) experiment at the Facility for Antiproton and Ion Research (FAIR). An effective meson model earlier developed, with mesonic and baryonic degrees of freedom in s , t , and u channels, is applied here to π0π0 production. Form factors with logarithmic s and t (u ) dependencies are applied. A fair agreement with the existing angular distributions is obtained. Applying SU(3) symmetry, it is straightforward to recover the angular distributions for π0η and η η production in the same energy range. A good agreement is generally obtained with all existing data.

  3. Limitations on anti p-p luminosity with direct injection and stacking of antiprotons

    International Nuclear Information System (INIS)

    Courant, E.D.; Teng, L.C.

    1979-01-01

    If protons of very high energy impinge on a target, a large part of the resulting antiprotons are sufficiently collimated to be injectible into a stacking and accelerating ring. They can then be stacked and injected into the main proton accelerator so as to produce anti p-p collisions without low energy antiproton cooling. A scheme is presented for the VBA, where 20 TeV protons produce 9 x 10 -4 antiprotons per proton at 100 GeV, which are then stacked, accelerated to 1 TeV, and injected into the main ring. With 16 proton pulses of 10 15 protons, one obtains a luminosity of the order of 10 32 cm -2 sec -1 with a beam-beam tune shift of 10 -3 per interaction region. The beams are bunched into 1000 bunches; the orbits are separated by means of relatively modest electostatic electrodes

  4. QCD studies with anti-protons at FAIR: Indian participation in PANDA

    International Nuclear Information System (INIS)

    Kailas, S.; Roy, B.J.; Dutta, D.; Jha, V.; Varma, R.

    2011-01-01

    The Facility for Antiproton and Ion Research (FAIR) is a future project at GSI which will extend hadron physics studies up to the charm meson region using antiproton beams together with a state-of-the-art detector antiproton annihilation at Darmstadt (PANDA). The physics aim, in a broader sense, is to address the fundamental problems of hadron physics and aspects of quantum chromo-dynamics (QCD) at low energies. The proposed work in India will consist of several parts: R and D studies of silicon micro-strip detector, development of a scintillator hodoscope with silicon photomultiplier (SiPM) readout, studies of SiPM as photon counter and simulation studies of the detector design as well as physics case studies. The present article describes the physics motivation and initial progress made towards achieving these goals. (author)

  5. Charge asymmetry in alignment of atoms excited by protons and antiprotons

    International Nuclear Information System (INIS)

    Balashov, V.V.; Sokolik, A.A.; Stysin, A.V.

    2007-01-01

    The multichannel diffraction approximation is used to consider excitation of lithium atom by proton and antiproton impact. Calculations are performed for the energy range 100 keV - 1 MeV of incoming proton and anti-proton which should be reliable enough due to the general requirements of the multichannel diffraction approximation. The sign-of-charge effect in the alignment of produced 1s 2 3d excited state and in the linear polarization of the subsequent spontaneous 1s 2 3d → 1s 2 2p radiation is expected to be considerable. The clear sign-of-charge effect in the polarization occurs for projectile energies below 1 MeV and become stronger when going to lower energies and the difference between the proton case and the anti-proton one looks considerable enough for experimental observation

  6. Depth-Dose and LET Distributions of Antiproton Beams in Various Target Materials

    DEFF Research Database (Denmark)

    Herrmann, Rochus; Olsen, Sune; Petersen, Jørgen B.B.

    the annihilation process. Materials We have investigated the impact of substituting the target material on  the depth-dose distribution of pristine and  spread out antiproton beams using the FLUKA Monte Carlo transport program. Classical ICRP targets are compared to water phantoms. In addition, track average...... unrestricted LET is calculated for all configurations. Finally, we investigate which concentrations of gadolinium and boron are needed in a water target in order to observe a significant change in the antiproton depth-dose distribution.  Results Results indicate, that there is no significant change...... in the depth-dose distribution and average LET when substituting the materials. Adding boron and gadolinium up to concentrations of 1 per 1000 atoms to a water phantom, did not change the depth-dose profile nor the average LET. Conclusions  According to our FLUKA calculations, antiproton neutron capture...

  7. Challenging the standard model by high-precision comparisons of the fundamental properties of protons and antiprotons

    Science.gov (United States)

    Ulmer, S.; Mooser, A.; Nagahama, H.; Sellner, S.; Smorra, C.

    2018-03-01

    The BASE collaboration investigates the fundamental properties of protons and antiprotons, such as charge-to-mass ratios and magnetic moments, using advanced cryogenic Penning trap systems. In recent years, we performed the most precise measurement of the magnetic moments of both the proton and the antiproton, and conducted the most precise comparison of the proton-to-antiproton charge-to-mass ratio. In addition, we have set the most stringent constraint on directly measured antiproton lifetime, based on a unique reservoir trap technique. Our matter/antimatter comparison experiments provide stringent tests of the fundamental charge-parity-time invariance, which is one of the fundamental symmetries of the standard model of particle physics. This article reviews the recent achievements of BASE and gives an outlook to our physics programme in the ELENA era. This article is part of the Theo Murphy meeting issue `Antiproton physics in the ELENA era'.

  8. Challenging the standard model by high-precision comparisons of the fundamental properties of protons and antiprotons.

    Science.gov (United States)

    Ulmer, S; Mooser, A; Nagahama, H; Sellner, S; Smorra, C

    2018-03-28

    The BASE collaboration investigates the fundamental properties of protons and antiprotons, such as charge-to-mass ratios and magnetic moments, using advanced cryogenic Penning trap systems. In recent years, we performed the most precise measurement of the magnetic moments of both the proton and the antiproton, and conducted the most precise comparison of the proton-to-antiproton charge-to-mass ratio. In addition, we have set the most stringent constraint on directly measured antiproton lifetime, based on a unique reservoir trap technique. Our matter/antimatter comparison experiments provide stringent tests of the fundamental charge-parity-time invariance, which is one of the fundamental symmetries of the standard model of particle physics. This article reviews the recent achievements of BASE and gives an outlook to our physics programme in the ELENA era.This article is part of the Theo Murphy meeting issue 'Antiproton physics in the ELENA era'. © 2018 The Authors.

  9. Propylthiouracil and peripheral neuropathy

    Directory of Open Access Journals (Sweden)

    Valentina Van Boekel

    1992-06-01

    Full Text Available Peripheral neuropathy is a rare manifestation in hyperthyroidism. We describe the neurological manifestations of a 38 year old female with Graves' disease who developed peripheral neuropathy in the course of her treatment with propylthiouracil. After the drug was tapered off, the neurological signs disappeared. Therefore, we call attention for a possible toxic effect on peripheral nervous system caused by this drug.

  10. Centrifugal Separation and Equilibration Dynamics in an Electron-Antiproton Plasma

    International Nuclear Information System (INIS)

    Andresen, G. B.; Bowe, P. D.; Hangst, J. S.; Ashkezari, M. D.; Hayden, M. E.; Baquero-Ruiz, M.; Chapman, S.; Fajans, J.; Povilus, A.; So, C.; Bertsche, W.; Butler, E.; Charlton, M.; Deller, A.; Eriksson, S.; Humphries, A. J.; Madsen, N.; Werf, D. P. van der; Cesar, C. L.; Friesen, T.

    2011-01-01

    Charges in cold, multiple-species, non-neutral plasmas separate radially by mass, forming centrifugally separated states. Here, we report the first detailed measurements of such states in an electron-antiproton plasma, and the first observations of the separation dynamics in any centrifugally separated system. While the observed equilibrium states are expected and in agreement with theory, the equilibration time is approximately constant over a wide range of parameters, a surprising and as yet unexplained result. Electron-antiproton plasmas play a crucial role in antihydrogen trapping experiments.

  11. Proton-Antiproton Pair Production in Two-Photon Collisions at LEP

    CERN Document Server

    Achard, P.; Aguilar-Benitez, M.; Alcaraz, J.; Alemanni, G.; Allaby, J.; Aloisio, A.; Alviggi, M.G.; Anderhub, H.; Andreev, Valery P.; Anselmo, F.; Arefev, A.; Azemoon, T.; Aziz, T.; Bagnaia, P.; Bajo, A.; Baksay, G.; Baksay, L.; Baldew, S.V.; Banerjee, S.; Banerjee, Sw.; Barczyk, A.; Barillere, R.; Bartalini, P.; Basile, M.; Batalova, N.; Battiston, R.; Bay, A.; Becattini, F.; Becker, U.; Behner, F.; Bellucci, L.; Berbeco, R.; Berdugo, J.; Berges, P.; Bertucci, B.; Betev, B.L.; Biasini, M.; Biglietti, M.; Biland, A.; Blaising, J.J.; Blyth, S.C.; Bobbink, G.J.; Bohm, A.; Boldizsar, L.; Borgia, B.; Bottai, S.; Bourilkov, D.; Bourquin, M.; Braccini, S.; Branson, J.G.; Brochu, F.; Burger, J.D.; Burger, W.J.; Cai, X.D.; Capell, M.; Cara Romeo, G.; Carlino, G.; Cartacci, A.; Casaus, J.; Cavallari, F.; Cavallo, N.; Cecchi, C.; Cerrada, M.; Chamizo, M.; Chang, Y.H.; Chemarin, M.; Chen, A.; Chen, G.; Chen, G.M.; Chen, H.F.; Chen, H.S.; Chiefari, G.; Cifarelli, L.; Cindolo, F.; Clare, I.; Clare, R.; Coignet, G.; Colino, N.; Costantini, S.; de la Cruz, B.; Cucciarelli, S.; van Dalen, J.A.; de Asmundis, R.; Deglon, P.; Debreczeni, J.; Degre, A.; Dehmelt, K.; Deiters, K.; della Volpe, D.; Delmeire, E.; Denes, P.; DeNotaristefani, F.; De Salvo, A.; Diemoz, M.; Dierckxsens, M.; Dionisi, C.; Dittmar, M.; Doria, A.; Dova, M.T.; Duchesneau, D.; Duda, M.; Echenard, B.; Eline, A.; El Hage, A.; El Mamouni, H.; Engler, A.; Eppling, F.J.; Extermann, P.; Falagan, M.A.; Falciano, S.; Favara, A.; Fay, J.; Fedin, O.; Felcini, M.; Ferguson, T.; Fesefeldt, H.; Fiandrini, E.; Field, J.H.; Filthaut, F.; Fisher, P.H.; Fisher, W.; Fisk, I.; Forconi, G.; Freudenreich, K.; Furetta, C.; Galaktionov, Iouri; Ganguli, S.N.; Garcia-Abia, Pablo; Gataullin, M.; Gentile, S.; Giagu, S.; Gong, Z.F.; Grenier, Gerald Jean; Grimm, O.; Gruenewald, M.W.; Guida, M.; van Gulik, R.; Gupta, V.K.; Gurtu, A.; Gutay, L.J.; Haas, D.; Hakobyan, R.S.; Hatzifotiadou, D.; Hebbeker, T.; Herve, Alain; Hirschfelder, J.; Hofer, H.; Hohlmann, M.; Holzner, G.; Hou, S.R.; Hu, Y.; Jin, B.N.; Jones, Lawrence W.; de Jong, P.; Josa-Mutuberria, I.; Kafer, D.; Kaur, M.; Kienzle-Focacci, M.N.; Kim, J.K.; Kirkby, Jasper; Kittel, W.; Klimentov, A.; Konig, A.C.; Kopal, M.; Koutsenko, V.; Kraber, M.; Kraemer, R.W.; Kruger, A.; Kunin, A.; Ladron de Guevara, P.; Laktineh, I.; Landi, G.; Lebeau, M.; Lebedev, A.; Lebrun, P.; Lecomte, P.; Lecoq, P.; Le Coultre, P.; Le Goff, J.M.; Leiste, R.; Levtchenko, M.; Levtchenko, P.; Li, C.; Likhoded, S.; Lin, C.H.; Lin, W.T.; Linde, F.L.; Lista, L.; Liu, Z.A.; Lohmann, W.; Longo, E.; Lu, Y.S.; Luci, C.; Luminari, L.; Lustermann, W.; Ma, W.G.; Malgeri, L.; Malinin, A.; Mana, C.; Mans, J.; Martin, J.P.; Marzano, F.; Mazumdar, K.; McNeil, R.R.; Mele, S.; Merola, L.; Meschini, M.; Metzger, W.J.; Mihul, A.; Milcent, H.; Mirabelli, G.; Mnich, J.; Mohanty, G.B.; Muanza, G.S.; Muijs, A.J.M.; Musicar, B.; Musy, M.; Nagy, S.; Natale, S.; Napolitano, M.; Nessi-Tedaldi, F.; Newman, H.; Nisati, A.; Kluge, Hannelies; Ofierzynski, R.; Organtini, G.; Pal, I.; Palomares, C.; Paolucci, P.; Paramatti, R.; Passaleva, G.; Patricelli, S.; Paul, Thomas Cantzon; Pauluzzi, M.; Paus, C.; Pauss, F.; Pedace, M.; Pensotti, S.; Perret-Gallix, D.; Petersen, B.; Piccolo, D.; Pierella, F.; Pioppi, M.; Piroue, P.A.; Pistolesi, E.; Plyaskin, V.; Pohl, M.; Pojidaev, V.; Pothier, J.; Prokofev, D.; Quartieri, J.; Rahal-Callot, G.; Rahaman, Mohammad Azizur; Raics, P.; Raja, N.; Ramelli, R.; Rancoita, P.G.; Ranieri, R.; Raspereza, A.; Razis, P.; Ren, D.; Rescigno, M.; Reucroft, S.; Riemann, S.; Riles, Keith; Roe, B.P.; Romero, L.; Rosca, A.; Rosier-Lees, S.; Roth, Stefan; Rosenbleck, C.; Rubio, J.A.; Ruggiero, G.; Rykaczewski, H.; Sakharov, A.; Saremi, S.; Sarkar, S.; Salicio, J.; Sanchez, E.; Schafer, C.; Schegelsky, V.; Schopper, H.; Schotanus, D.J.; Sciacca, C.; Servoli, L.; Shevchenko, S.; Shivarov, N.; Shoutko, V.; Shumilov, E.; Shvorob, A.; Son, D.; Souga, C.; Spillantini, P.; Steuer, M.; Stickland, D.P.; Stoyanov, B.; Straessner, A.; Sudhakar, K.; Sultanov, G.; Sun, L.Z.; Sushkov, S.; Suter, H.; Swain, J.D.; Szillasi, Z.; Tang, X.W.; Tarjan, P.; Tauscher, L.; Taylor, L.; Tellili, B.; Teyssier, D.; Timmermans, Charles; Ting, Samuel C.C.; Ting, S.M.; Tonwar, S.C.; Toth, J.; Tully, C.; Tung, K.L.; Ulbricht, J.; Valente, E.; Van de Walle, R.T.; Vasquez, R.; Veszpremi, V.; Vesztergombi, G.; Vetlitsky, I.; Vicinanza, D.; Viertel, G.; Villa, S.; Vivargent, M.; Vlachos, S.; Vodopianov, I.; Vogel, H.; Vogt, H.; Vorobev, I.; Vorobyov, A.A.; Wadhwa, M.; Wang, Q.; Wang, X.L.; Wang, Z.M.; Weber, M.; Wienemann, P.; Wilkens, H.; Wynhoff, S.; Xia, L.; Xu, Z.Z.; Yamamoto, J.; Yang, B.Z.; Yang, C.G.; Yang, H.J.; Yang, M.; Yeh, S.C.; Zalite, An.; Zalite, Yu.; Zhang, Z.P.; Zhao, J.; Zhu, G.Y.; Zhu, R.Y.; Zhuang, H.L.; Zichichi, A.; Zimmermann, B.; Zoller, M.

    2003-01-01

    The reaction e+e- -> e+e- proton antiproton is studied with the L3 detector at LEP. The analysis is based on data collected at e+e- center-of-mass energies from 183 GeV to 209 GeV, corresponding to an integrated luminosity of 667 pb-1. The gamma gamma -> proton antiproton differential cross section is measured in the range of the two-photon center-of-mass energy from 2.1 GeV to 4.5 GeV. The results are compared to the predictions of the three-quark and quark-diquark models.

  12. A possible method to produce a polarized antiproton beam at intermediate energies

    International Nuclear Information System (INIS)

    Spinka, H.; Vaandering, E.W.; Hofmann, J.S.

    1994-01-01

    A feasible and conservative design for a medium energy polarized antiproton beam has been presented. The design requires an intense beam of unpolarized antiprotons (≥ 10 7 /sec) from a typical secondary beam line in order to achieve reasonable anti pp elastic scattering count rates. All three beam spin directions can be achieved. Methods were discussed to reverse the spin directions in modest times, and to change to a polarized proton beam if desired. It is expected that experiments with such a beam would have a profound effect on the understanding of the anti NN interaction at intermediate energies

  13. Current status of antiproton impact ionization of atoms and molecules: theoretical and experimental perspectives

    DEFF Research Database (Denmark)

    Kirchner, Tom; Knudsen, Helge

    2011-01-01

    Experimental and theoretical progress in the field of antiproton-impact-induced ionization of atoms and molecules is reviewed. We describe the techniques used to measure ionization cross sections and give an overview of the experimental results supplemented by tables of all existing data. An atte......Experimental and theoretical progress in the field of antiproton-impact-induced ionization of atoms and molecules is reviewed. We describe the techniques used to measure ionization cross sections and give an overview of the experimental results supplemented by tables of all existing data...

  14. An apparatus to measure stopping powers for low-energy antiprotons and protons

    CERN Document Server

    Andersen, H H; Ichioka, T; Knudsen, H; Møller, S P; Uggerhøj, U

    2002-01-01

    One of the experiments to be performed under the ASACUSA collaboration at the CERN Antiproton Decelerator is a measurement of the energy loss of low energy antiprotons in thin foils. An electrostatic spectrometer has been developed for this task. We describe the design and initial tests of the apparatus with protons. By changing a high-voltage applied on the target the energy of the projectile ions at impact on the target can easily be varied. In this way we have measured the stopping-power and the energy-loss straggling for protons over a wide energy range to below one keV.

  15. Centrifugal separation and equilibration dynamics in an electron-antiproton plasma

    CERN Document Server

    Andresen, G B; Baquero-Ruiz, Marcelo; Bertsche, William; Bowe, Paul D; Butler, Eoin; Cesar, Claudio L; Chapman, Steven; Charlton, Michael; Deller, A; Eriksson, S; Fajans, Joel; Friesen, Tim; Fujiwara, Makoto C; Gill, David R; Gutierrez, A; Hangst, Jeffrey S; Hardy, Walter N; Hayden, Michael E; Humphries, Andrew J; Hydomako, Richard; Jonsell, Svante; Madsen, Niels; Menary, Scott; Nolan, Paul; Olin, Art; Povilus, Alexander; Pusa, Petteri; Robicheaux, Francis; Sarid, Eli; Silveira, Daniel M; So, Chukman; Storey, James W; Thompson, Robert I; van der Werf, Dirk P; Wurtele, Jonathan S; Yamazaki, Yasunori

    2011-01-01

    Charges in cold, multiple-species, non-neutral plasmas separate radially by mass, forming centrifugally-separated states. Here, we report the first detailed measurements of such states in an electron-antiproton plasma, and the first observations of the separation dynamics in any centrifugally-separated system. While the observed equilibrium states are expected and in agreement with theory, the equilibration time is approximately constant over a wide range of parameters, a surprising and as yet unexplained result. Electron-antiproton plasmas play a crucial role in antihydrogen trapping experiments.

  16. Scattering of antiprotons from carbon at 46.8 MeV

    International Nuclear Information System (INIS)

    Garetta, D.; Birien, P.; Bruge, G.; Chaumeaux, A.; Janouin, S.; Legrand, D.; Mallet-Lemaire, M.C.; Mayer, B.; Pain, J.; Drake, D.M.; Peng, J.C.

    1984-01-01

    Antiproton-carbon elastic and inelastic scattering cross sections have been measured at 46.8 MeV over an angular range 6 0 0 with a magnetic spectrometer. Fits to the elastic and inelastic 4.44 MeV excited state cross sections put realistic limits on the strengths of the real and imaginary parts of the antiproton-carbon optical potential. The continuum cross section due to carbon break-up appears to be smaller than it is for corresponding proton data. (orig.)

  17. First observation of laser-induced resonant annihilation in metastable antiprotonic helium atoms

    International Nuclear Information System (INIS)

    Morita, N.; Kumakura, M.; Yamazaki, T.

    1993-11-01

    We have observed the first laser-induced resonant transitions in antiprotonic helium atoms. These occur between metastable states and Auger dominated short lived states, and show that the anomalous longevity of antiprotons previously observed in helium media results from the formation of high-n high-l atomic states of p-barHe + . The observed transition with vacuum wavelength 597.259 ± 0.002 nm and lower-state lifetime 15 ± 1 ns is tentatively assigned to (n,l) = (39,35) → (38,34). (author)

  18. Effect of radiotherapy on lymphocyte cytotoxicity against allogeneic lung cancer cells in patients with bronchogenic carcinoma

    International Nuclear Information System (INIS)

    Toyohira, Ken; Yasumoto, Kosei; Manabe, Hideo; Ohta, Mitsuo; Terashima, Hiromi

    1979-01-01

    Cytotoxicity of peripheral blood lymphocytes against allogeneic target cells of bronchogenic carcinoma was examined by a microcytotoxicity test before, during, and after radiotherapy in primary lung cancer patients. Before the treatment, cytotoxicity was depressed only slightly in patients in stage III and strikingly in those in stage IV, as compared to the values in patients at earlier stages of lung cancer such as stages I and II. Local irradiation scarcely affected cytotoxicity at stages II and III, but augmented remarkably at stage IV. The number of peripheral blood lymphocytes decreased profoundly during and after radiotherapy in all cases of stages II, III, and IV. Although radiotherapy exhibited various effects on the cytotoxic activity of lymphocytes and the number of peripheral blood lymphocytes, only the cytotoxic activity at the end of radiotherapy correlated well with the reduction in tumor size. (author)

  19. Peripheral Neuropathy and Agent Orange

    Science.gov (United States)

    ... Enter ZIP code here Enter ZIP code here Peripheral Neuropathy and Agent Orange VA presumes Veterans' early-onset ... 10 percent disabling by VA's rating regulations. About peripheral neuropathy Peripheral neuropathy is a condition of the peripheral ...

  20. Populations and lifetimes in the $v=n-l-1=2$ and 3 metastable cascades of $\\overline{p} He^{+}$ measured by pulsed and continuous antiproton beams

    CERN Document Server

    Hori, Masaki; Widmann, E; Yamazaki, T; Hayano, R S; Ishikawa, T; Torie, H A; Von Egidy, T; Hartmann, F; Ketzer, B; Maierl, C; Pohl, R; Kumakura, M; Morita, N; Horváth, D; Sugai, I

    2004-01-01

    Using the laser spectroscopy, the time evolution of the state population in the v equivalent n-l=2 and 3 metastable cascades of antiprotonic helium atoms were studied. The effects of the collision between antiprotonic helium and the ordinary helium atoms on the atomic cascade were also analyzed. The measurements were done using the pulsed and continuous types of antiproton beams supplied by the Low Energy Antiproton Ring. The studies revealed five phases in the life history of the metastable antiprotonic helium. (Edited abstract) 71 Refs.

  1. Buffer-gas cooling of antiprotonic helium to 1.5 to 1.7 K, and antiproton-to–electron mass ratio

    CERN Document Server

    Hori, Masaki; Sótér, Anna; Barna, Daniel; Dax, Andreas; Hayano, Ryugo; Kobayashi, Takumi; Murakami, Yohei; Todoroki, Koichi; Yamada, Hiroyuki; Horváth, Dezső; Venturelli, Luca

    2016-01-01

    Charge, parity, and time reversal (CPT) symmetry implies that a particle and its antiparticle have the same mass. The antiproton-to-electron mass ratio Embedded Image can be precisely determined from the single-photon transition frequencies of antiprotonic helium. We measured 13 such frequencies with laser spectroscopy to a fractional precision of 2.5 × 10−9 to 16 × 10−9. About 2 × 109 antiprotonic helium atoms were cooled to temperatures between 1.5 and 1.7 kelvin by using buffer-gas cooling in cryogenic low-pressure helium gas; the narrow thermal distribution led to the observation of sharp spectral lines of small thermal Doppler width. The deviation between the experimental frequencies and the results of three-body quantum electrodynamics calculations was reduced by a factor of 1.4 to 10 compared with previous single-photon experiments. From this, Embedded Image was determined as 1836.1526734(15), which agrees with a recent proton-to-electron experimental value within 8 × 10−10.

  2. Occupational genetic risks for nurses at radiotherapy oncology wards

    Energy Technology Data Exchange (ETDEWEB)

    Srb, V; Kubzova, E

    1985-05-31

    A lymphocyte chromosome analysis of short-term cultured whole peripheral blood of 14 nurses in the radiotherapy/oncology ward of the radiological clinic (working in health risk conditions for an average of 14 years) classified them into a high risk genetic group. They were found to have 4.7% cells with chromosomal aberrations as compared with 1.5% such cells in the control group. The said difference had a high statistical significance (p<0.001). Only aberrations of the structural type were evaluated.The mitotic activity of peripheral blood lymphocytes in the study group was also adversely affected (MI=1.8) compared with the control group (MI=2.9). Cytogenetic peripheral lymphocyte analysis used as a collective biological exposure test is being considered for incorporation in the system of preventive medical chec-kups of nurses working in radiotherapy/oncology wards.

  3. Occupational genetic risks for nurses at radiotherapy oncology wards

    International Nuclear Information System (INIS)

    Srb, V.; Kubzova, E.

    1985-01-01

    A lymphocyte chromosome analysis of short-term cultured whole peripheral blood of 14 nurses in the radiotherapy/oncology ward of the radiological clinic (working in health risk conditions for an average of 14 years) classified them into a high risk genetic group. They were found to have 4.7% cells with chromosomal aberrations as compared with 1.5% such cells in the control group. The said difference had a high statistical significance (p<0.001). Only aberrations of the structural type were evaluated.The mitotic activity of peripheral blood lymphocytes in the study group was also adversely affected (MI=1.8) compared with the control group (MI=2.9). Cytogenetic peripheral lymphocyte analysis used as a collective biological exposure test is being considered for incorporation in the system of preventive medical chec-kups of nurses working in radiotherapy/oncology wards. (author)

  4. Peripheral doses from pediatric IMRT

    International Nuclear Information System (INIS)

    Klein, Eric E.; Maserang, Beth; Wood, Roy; Mansur, David

    2006-01-01

    Peripheral dose (PD) data exist for conventional fields (≥10 cm) and intensity-modulated radiotherapy (IMRT) delivery to standard adult-sized phantoms. Pediatric peripheral dose reports are limited to conventional therapy and are model based. Our goal was to ascertain whether data acquired from full phantom studies and/or pediatric models, with IMRT treatment times, could predict Organ at Risk (OAR) dose for pediatric IMRT. As monitor units (MUs) are greater for IMRT, it is expected IMRT PD will be higher; potentially compounded by decreased patient size (absorption). Baseline slab phantom peripheral dose measurements were conducted for very small field sizes (from 2 to 10 cm). Data were collected at distances ranging from 5 to 72 cm away from the field edges. Collimation was either with the collimating jaws or the multileaf collimator (MLC) oriented either perpendicular or along the peripheral dose measurement plane. For the clinical tests, five patients with intracranial or base of skull lesions were chosen. IMRT and conventional three-dimensional (3D) plans for the same patient/target/dose (180 cGy), were optimized without limitation to the number of fields or wedge use. Six MV, 120-leaf MLC Varian axial beams were used. A phantom mimicking a 3-year-old was configured per Center for Disease Control data. Micro (0.125 cc) and cylindrical (0.6 cc) ionization chambers were appropriated for the thyroid, breast, ovaries, and testes. The PD was recorded by electrometers set to the 10 -10 scale. Each system set was uniquely calibrated. For the slab phantom studies, close peripheral points were found to have a higher dose for low energy and larger field size and when MLC was not deployed. For points more distant from the field edge, the PD was higher for high-energy beams. MLC orientation was found to be inconsequential for the small fields tested. The thyroid dose was lower for IMRT delivery than that predicted for conventional (ratio of IMRT/cnventional ranged from

  5. Closing in on mass-degenerate dark matter scenarios with antiprotons and direct detection

    International Nuclear Information System (INIS)

    Garny, Mathias; Ibarra, Alejandro; Pato, Miguel; Vogl, Stefan

    2012-01-01

    Over the last years both cosmic-ray antiproton measurements and direct dark matter searches have proved particularly effective in constraining the nature of dark matter candidates. The present work focusses on these two types of constraints in a minimal framework which features a Majorana fermion as the dark matter particle and a scalar that mediates the coupling to quarks. Considering a wide range of coupling schemes, we derive antiproton and direct detection constraints using the latest data and paying close attention to astrophysical and nuclear uncertainties. Both signals are strongly enhanced in the presence of degenerate dark matter and scalar masses, but we show that the effect is especially dramatic in direct detection. Accordingly, the latest direct detection limits take the lead over antiprotons. We find that antiproton and direct detection data set stringent lower limits on the mass splitting, reaching 19% at a 300 GeV dark matter mass for a unity coupling. Interestingly, these limits are orthogonal to ongoing collider searches at the Large Hadron Collider, making it feasible to close in on degenerate dark matter scenarios within the next years

  6. An Antiproton Ion Collider (AIC) for Measuring Neutron and Proton Distributions in Stable and Radioactive Nuclei

    International Nuclear Information System (INIS)

    Kienle, Paul

    2005-01-01

    An antiproton-ion collider is proposed to independently determine mean square radii for protons and neutrons in stable and short lived nuclei by means of antiproton absorption at medium energies. The experiment makes use of the electron ion collider complex (ELISE) of the GSI FAIR project with appropriate modifications of the electron ring to store, cool and collide antiprotons of 30 MeV energy with 740A MeV energy ions.The total absorption cross-section of antiprotons by the stored ions will be measured by detecting their loss by means of the Schottky noise spectroscopy method. Cross sections for the absorption on protons and neutrons, respectively, will be studied by detection of residual nuclei with A-1 either by the Schottky method or by analysing them in recoil detectors after the first dipole stage of the NESR following the interaction zone. With a measurement of the A-1 fragment momentum distribution, one can test the momentum wave functions of the annihilated neutron and proton, respectively. Furthermore by changing the incident ion energy the tails of neutron and proton distribution can be measured.The absorption cross section is at asymptotic energies in leading order proportional to the mean square radius of the nucleus. Predicted cross sections and luminosities show that the method is applicable to nuclei with production rates of about 105 s-1 or lower, depending on the lifetime of the ions in the NESR, and for half-lives down to 1 second

  7. S142 set-up to detect X-ray from antiproton-proton atoms (protonium).

    CERN Multimedia

    1978-01-01

    This experiment was designed by the Daresbury-Mainz-TRIUMF Collaboration and was located in the m14 partially separated antiproton beam in the PS South Hall. It used a gaseous hydrogen target, 1 m long, surrounded by a ring of proportional counters, surrounded in turn by a ring of 36 scintillators strips to aid in the annihilation product identification. Ugo Gastaldi (centre)

  8. Antiproton-proton elastic scattering at 1.8 TeV

    International Nuclear Information System (INIS)

    Fazal-e-Aleem; Saleem, M.; Yodh, G.B.

    1990-01-01

    The predictions, based on the generalized Chou-Yang model, are made for the most recent measurements of antiproton-proton elastic scattering at √s = 1.8 TeV. These results have been compared with the recent theoretical predictions of various models. (author)

  9. Antiproton-proton elastic scattering at 1. 8 TeV

    Energy Technology Data Exchange (ETDEWEB)

    Fazal-e-Aleem; Saleem, M. (Punjab Univ., Lahore (Pakistan). Centre for High Energy Physics); Yodh, G.B. (California Univ., Irvine, CA (USA). Dept. of Physics)

    1990-11-01

    The predictions, based on the generalized Chou-Yang model, are made for the most recent measurements of antiproton-proton elastic scattering at {radical}s = 1.8 TeV. These results have been compared with the recent theoretical predictions of various models. (author).

  10. Closing in on mass-degenerate dark matter scenarios with antiprotons and direct detection

    Energy Technology Data Exchange (ETDEWEB)

    Garny, Mathias [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Ibarra, Alejandro; Pato, Miguel; Vogl, Stefan [Technische Univ. Muenchen, Garching (Germany). Physik-Department

    2012-07-15

    Over the last years both cosmic-ray antiproton measurements and direct dark matter searches have proved particularly effective in constraining the nature of dark matter candidates. The present work focusses on these two types of constraints in a minimal framework which features a Majorana fermion as the dark matter particle and a scalar that mediates the coupling to quarks. Considering a wide range of coupling schemes, we derive antiproton and direct detection constraints using the latest data and paying close attention to astrophysical and nuclear uncertainties. Both signals are strongly enhanced in the presence of degenerate dark matter and scalar masses, but we show that the effect is especially dramatic in direct detection. Accordingly, the latest direct detection limits take the lead over antiprotons. We find that antiproton and direct detection data set stringent lower limits on the mass splitting, reaching 19% at a 300 GeV dark matter mass for a unity coupling. Interestingly, these limits are orthogonal to ongoing collider searches at the Large Hadron Collider, making it feasible to close in on degenerate dark matter scenarios within the next years.

  11. Relative Biological Effect of Antiprotons

    DEFF Research Database (Denmark)

    Bassler, Niels; Holzscheiter, Michael

    nuclear research facility CERN. A beam of 126 MeV antiprotons, corresponding to about 12 cm range in water, was spread out to a SOBP with a width of 1 cm. Dosimetry experiments were carried out with ionization chambers, alanine pellets and radiochromic film, and the results were used for benchmarking...

  12. Spin observables in antiproton-proton to AntiLambda-Lambda and density-matrix constraints

    OpenAIRE

    Elchikh, Mokhtar; Richard, Jean-Marc

    2005-01-01

    The positivity conditions of the spin density matrix constrain the spin observables of the reaction antiproton-proton to AntiLambda-Lambda, leading to model-independent, non-trivial inequalities. The formalism is briefly presented and examples of inequalities are provided.

  13. Measurement of 0.25-3.2 GeV antiprotons in the cosmic radiation

    DEFF Research Database (Denmark)

    Mitchell, J.W.; Barbier, L.M.; Christian, E.R.

    1996-01-01

    The balloon-borne Isotope Matter-Antimatter Experiment (IMAX) was flown from Lynn Lake, Manitoba, Canada on 16-17 July 1992. Using velocity and magnetic rigidity to determine mass, we have directly measured the abundances of cosmic ray antiprotons and protons in the energy range from 0.25 to 3.2 ...

  14. Proton and antiproton interactions in hydrogen, argon and xenon at 200 GeV

    International Nuclear Information System (INIS)

    Malecki, P.

    1984-01-01

    The detailed analysis of the production of particles emitted into forward hemisphere in 200 GeV proton and antiproton interactions with hydrogen, argon and xenon targets is presented. Two-particle rapidity correlations and long-range multiplicity correlations are also discussed. (author)

  15. A method to study the antiproton-proton annihilation at rest

    International Nuclear Information System (INIS)

    Bigi, A.

    1977-01-01

    The comparison between at rest and in flight antiproton-proton annihilations cannot be extended in terms of kinematical variables referred to the collision axis that is not defined for the at rest interactions. On the basis of the momentum vectors of the final state particles, other directions can be defined, event by event, and used as reference frame

  16. Antiproton-nucleus interactions at 5 to 9 GeV/c

    International Nuclear Information System (INIS)

    Ahmad, S.; Bonner, B.E.; Buchanan, J.A.; Chan, C.S.; Clement, J.M.; Eiseman, S.E.; Empl, A.; Etkin, A.; Foley, K.J.; Hackenburg, R.W.; Hallman, T.J.; Kramer, M.A.; Kruk, J.; Lindenbaum, S.J.; Longacre, R.S.; Love, W.A.; Madansky, L.; Morris, W.; Mutchler, G.S.; Peaslee, D.C.; Platner, E.D.; Saulys, A.C.; Toshkov, S.

    1993-01-01

    Antiproton beams of 5, 7 and 9 GeV/c were used to interact with C, Al, Cu, Sn and Pb nuclear targets. Charged particle multiplicity distributions, strange particle production cross sections and rapidity distributions were measured. The charged particle multiplicities are reported in this paper. (orig.)

  17. Challenging the Standard Model: High-Precision Comparisons of the Fundamental Properties of Protons and Antiprotons

    CERN Multimedia

    CERN. Geneva

    2018-01-01

    The Baryon Antibaryon Symmetry Experiment (BASE-CERN) at CERN’s antiproton decelerator facility is aiming at high-precision comparisons of the fundamental properties of protons and antiprotons, such as charge-to-mass ratios, magnetic moments and lifetimes. Such experiments provide sensitive tests of the fundamental charge-parity-time invariance in the baryon sector. BASE was approved in 2013 and has measured since then, utilizing single-particle multi-Penning-trap techniques, the antiproton-to-proton charge-to-mass ratio with a fractional precision of 69 p.p.t. [1], as well as the antiproton magnetic moment with fractional precisions of 0.8 p.p.m. and 1.5 p.p.b., respectively [2]. At our matter companion experiment BASE-Mainz, we have performed proton magnetic moment measurements with fractional uncertainties of 3.3 p.p.b. [3] and 0.3 p.p.b. [4]. By combining the data of both experiments we provide a baryon-magnetic-moment based CPT test gpbar/gp = 1.000 000 000 2(15), which improves the uncertainty of p...

  18. Analysis of the efficacy and safety of conventional radiotherapy of chest wall and clavicular field and three-dimensional conformal radiotherapy in patients after modified radical mastectomy

    Directory of Open Access Journals (Sweden)

    Song-Lin Wang

    2017-04-01

    Full Text Available Objective: To explore the efficacy and safety of conventional radiotherapy of chest wall and clavicular field and three-dimensional conformal radiotherapy in patients after modified radical mastectomy. Methods: A total of 84 patients who were admitted in our hospital after modified radical mastectomy were included in the study and divided into the conventional radiotherapy group (n=42 and the three-dimensional conformal radiotherapy group (n=42 according to different radiotherapy methods. The patients in the conventional radiotherapy group were given conventional radiotherapy of chest wall and clavicular field, while the patients in the three-dimensional conformal radiotherapy group were given three-dimensional conformal radiotherapy. The serum tumor markers and peripheral blood T lymphocyte subsets 6-8 weeks after treatment in the two groups were detected. The clinical efficacy, and toxic and side effects in the two groups were evaluated. Results: The serum CA15-3, CA125, CEA, and CK19 levels after treatment in the two groups were significantly reduced when compared with before treatment, CD3 +,CD4 +, and CD4 +/CD8 + were significantly elevated, while CD8 + was significantly reduced when compared with before treatment, but the comparison of the above indicators between the two groups was not statistically significant. The occurrence rate of radioactive skin damage and pneumonia after treatment in the conventional radiotherapy group was significantly higher than that in the three-dimensional conformal radiotherapy group. Conclusions: The two kinds of radiotherapy schemes have an equal efficacy, but the toxic and side effects of three-dimensional conformal radiotherapy are significantly lower than those by the conventional radiotherapy, with a certain advantage.

  19. The metabolic radiotherapy. La radiotherapie metabolique

    Energy Technology Data Exchange (ETDEWEB)

    Begon, F.; Gaci, M. (Centre Hospitalier Universitaire, 86 - Poitiers (France))

    In this article, the authors recall the principles of the metabolic radiotherapy and present these main applications in the treatment of thyroid cancers, hyperthyroidism, polycythemia, arthritis, bone metastases, adrenergic neoplasms. They also present the radioimmunotherapy.

  20. Contribution of radiotherapy to the treatment of malignant tumors, 3. Combined drugs and radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Niibe, Hideo; Takahashi, Iku; Tamaki, Yoshio (Gunma Univ., Maebashi (Japan). School of Medicine)

    1984-09-01

    Effects of cytotoxic agent, hormone, hypoxic cell sensitizer, and radiation protector combined with radiation therapy in cancer management were analysed. The results were as follows: 1) An increase in response was seen in 25% or more of tumor nodules given radiotherapy combined with misonidazole, anoxic cell sensitizer, compared with radiotherpy alone. But the drug was also found to be neurotoxic and peripheral neuropathy. 2) Evidence has been given that Amifostine may protect the mucosal damage from radiation when Amifostine prior to irradiation was administrated to patients with tumor in the head and neck or in the pelvis. 3) There were no difference between five year survival of radiotherapy alone and with chemotherapy for patients with stage I Non-Hodgkin lymphoma. Chemotherapy following radiotherapy for patients with stage II was more effective treatment method than radiotherapy alone. 4) Radiotherapy for patients with prostate cancer was performed to control only primary site. The success rates of local control were over 80%. The near future holds extensive promise for a combination of radiation therapy, cytotoxic chemotherapy, hormone therapy, hypoxic cell sensitizer, and radiation protectors. All of these when used in the appropriate circumstances may yield significant improvements in the therapeutic ratio and in the long-tern control of tumors.

  1. Malignant Peripheral Nerve Sheath Tumour of the Maxilla

    Directory of Open Access Journals (Sweden)

    Puja Sahai

    2014-01-01

    Full Text Available A 38-year-old man was diagnosed with malignant peripheral nerve sheath tumour of the maxilla. He was treated with total maxillectomy. Histopathological examination of the resected specimen revealed a close resection margin. The tumour was of high grade with an MIB-1 labelling index of almost 60%. At six weeks following the surgery, he developed local tumour relapse. The patient succumbed to the disease at five months from the time of diagnosis. The present report underlines the locally aggressive nature of malignant peripheral nerve sheath tumour of the maxilla which necessitates an early therapeutic intervention. A complete resection with clear margins is the most important prognostic factor for malignant peripheral nerve sheath tumour in the head and neck region. Adjuvant radiotherapy may be considered to improve the local control. Future research may demarcate the role of targeted therapy for patients with malignant peripheral nerve sheath tumour.

  2. Study of the anti-hydrogen atom and ion formation in the collisions antiproton-positronium

    International Nuclear Information System (INIS)

    Comini, Pauline

    2014-01-01

    The future CERN experiment called GBAR intends to measure the gravitational acceleration of antimatter on Earth using cold (neV) anti-hydrogen atoms undergoing a free fall. The experiment scheme first needs to cool anti-hydrogen positive ions, obtained thanks to two consecutive reactions occurring when an antiproton beam collides with a dense positronium cloud.The present thesis studies these two reactions in order to optimise the production of the anti-ions. The total cross sections of both reactions have been computed in the framework of a perturbation theory model (Continuum Distorted Wave - Final State), in the range 0 to 30 keV antiproton kinetic energy; several excited states of positronium have been investigated. These cross sections have then been integrated to a simulation of the interaction zone where antiprotons collide with positronium; the aim is to find the optimal experimental parameters for GBAR. The results suggest that the 2P, 3D or, to a lower extend, 1S states of positronium should be used, respectively with 2, less than 1 or 6 keV antiprotons. The importance of using short pulses of antiprotons has been underlined; the positronium will have to be confined in a tube of 20 mm length and 1 mm diameter. In the prospect of exciting the 1S-3D two-photon transition in positronium at 410 nm, a pulsed laser system had already been designed. It consists in the frequency doubling of an 820 nm pulsed titanium-sapphire laser. The last part of the thesis has been dedicated to the realisation of this laser system, which delivers short pulses (9 ns) of 4 mJ energy at 820 nm. (author) [fr

  3. Radiotherapy in small countries.

    Science.gov (United States)

    Barton, Michael B; Zubizarreta, Eduardo H; Polo Rubio, J Alfredo

    2017-10-01

    To examine the availability of radiotherapy in small countries. A small country was defined as a country with a population less than one million persons. The economic status of each country was defined using the World Bank Classification. The number of cancers in each country was obtained from GLOBOCAN 2012. The number of cancer cases with an indication or radiotherapy was calculated using the CCORE model. There were 41 countries with a population of under 1 million; 15 were classified as High Income, 15 Upper Middle Income, 10 Lower Middle Income and one Low Income. 28 countries were islands. Populations ranged from 799 (Holy See) to 886450 (Fiji) and the total number of cancer cases occurring in small countries was 21,043 (range by country from 4 to 2476). Overall the total number of radiotherapy cases in small countries was 10982 (range by country from 2 to 1239). Radiotherapy was available in all HIC islands with 80 or more new cases of cancer in 2012 but was not available in any LMIC island. Fiji was the only LMIC island with a large radiotherapy caseload. Similar caseloads in non-island LMIC all had radiotherapy services. Most non-island HIC did not have radiotherapy services presumably because of the easy access to radiotherapy in neighbouring countries. There are no radiotherapy services in any LMIC islands. Copyright © 2017. Published by Elsevier Ltd.

  4. Experimental determination of the complete spin structure for anti-proton + proton -> anti-\\Lambda + \\Lambda at anti-proton beam momentum of 1.637 GeV/c

    CERN Document Server

    Paschke, K.D.; Berdoz, A.; Franklin, G.B.; Khaustov, P.; Meyer, C.A.; Bradtke, C.; Gehring, R.; Goertz, S.; Harmsen, J.; Meier, A.; Meyer, W.; Radtke, E.; Reicherz, G.; Dutz, H.; Pluckthun, M.; Schoch, B.; Dennert, H.; Eyrich, W.; Hauffe, J.; Metzger, A.; Moosburger, M.; Stinzing, F.; Wirth, St.; Fischer, H.; Franz, J.; Heinsius, F.H.; Kriegler, E.; Schmitt, H.; Bunker, B.; Hertzog, D.; Jones, T.; Tayloe, R.; Broders, R.; Geyer, R.; Kilian, K.; Oelert, W.; Rohrich, K.; Sachs, K.; Sefzick, T.; Bassalleck, B.; Eilerts, S.; Fields, D.E.; Kingsberry, P.; Lowe, J.; Stotzer, R.; Johansson, T.; Pomp, S.; Wirth, St.

    2006-01-01

    The reaction anti-proton + proton -> anti-\\Lambda + \\Lambda -> anti-proton + \\pi^+ + proton + \\pi^- has been measured with high statistics at anti-proton beam momentum of 1.637 GeV/c. The use of a transversely-polarized frozen-spin target combined with the self-analyzing property of \\Lambda/anti-\\Lambda decay allows access to unprecedented information on the spin structure of the interaction. The most general spin-scattering matrix can be written in terms of eleven real parameters for each bin of scattering angle, each of these parameters is determined with reasonable precision. From these results all conceivable spin-correlations are determined with inherent self-consistency. Good agreement is found with the few previously existing measurements of spin observables in anti-proton + proton -> anti-\\Lambda + \\Lambda near this energy. Existing theoretical models do not give good predictions for those spin-observables that had not been previously measured.

  5. Measure of back angle cross sections of antiproton-nucleus elastic scattering at 48 and 180 MeV

    International Nuclear Information System (INIS)

    Berrada, M.

    1986-04-01

    Antiproton-nucleus elastic scattering was studied in the LEAR ring at CERN. The scattering cross section at back angles (θ LAB = 142 to 164 deg inclusive) was measured using plastic scintillation detectors. Analysis of experimental data at 47 MeV for a CH target and at 182 MeV for CH, C12, 016, and 018 targets produces differential cross sections for back angles less than or equal to a few dozen microbarns. These results agree with theoretical microscopic predictions. The analysis improves understanding of antiproton-nucleus interaction and introduces a constraint on the construction of optical potentials. The antiproton-nucleus potential is shown to be highly absorbing, thereby excluding S type potentials, and removing the ambiguity arising from the analysis of antiprotonic atoms. The results also show that there is no attractive pocket in the real potential likely to lead to an increase of the back angle cross sections [fr

  6. Charm Production in Interactions of Antiproton with Proton and Nuclei at \\bar{it{P}}it{ANDA} Energies

    Science.gov (United States)

    Shyam, R.; Tsushima, K.

    2018-05-01

    We study the production of charmed baryons in the antiproton-proton and antiproton-nucleus interactions within a fully covariant model that is based on an effective Lagrangian approach. The baryon production proceeds via the t-channel D^0 and D^{*0} meson-exchange diagrams. We have also explored the production of the charm-baryon hypernucleus ^{16}_{Λ_c^+}O in the antiproton-^{16}O collisions. For antiproton beam momenta of interest to the {\\bar{P}}ANDA experiment, the 0° differential cross sections for the formation of ^{16}_{Λ_c^+}O hypernuclear states with simple particle-hole configurations, have magnitudes in the range of a few μ b/sr.

  7. The measurement of antiproton-proton total cross sections and small-angle elastic scattering at low momentum

    International Nuclear Information System (INIS)

    Linssen, L.H.A.J.

    1986-01-01

    In this thesis two low-momentum antiproton-proton (anti pp) experiments are described. The first one is a set of 24 high statistics anti pp total cross section measurements as a function of the incoming antiproton momentum between p=388 MeV/c and p=599 MeV/c. These measurements simultaneously yield the charge exchange cross section (anti pp → anti nn). The second one comprises two high statistics anti pp small-angle elastic scattering measurements at p=233 MeV/c and p=272 MeV/c. The measurements were carried out using the high quality antiproton beam extracted from the Low Energy Antiproton Ring (LEAR) at CERN. The physics motivation for these experiments is a search for anti pp resonances or bound states on one hand, and a detailed study of the anti pp interaction on the other hand. (orig.)

  8. Vasculitic peripheral neuropathy

    Directory of Open Access Journals (Sweden)

    Mona Amini

    2014-02-01

    Full Text Available Primary systemic vasculitis in pre-capillary arteries is associated with peripheral neuropathy. In some types of systematic vasculitis about 60 % of patients have peripheral nervous system (PNS involvement. In vasculitic peripheral neuropathies (VPN a necrotizing and inflammatory process leads to narrowing of vasa nervorum lumen and eventually the appearance of ischemic lesions in peripheral nerves. Some features might be suggestive of VPN, like: axonal nerve degeneration, wallerian-like degeneration, and diameter irregularity of nerve. Peripheral nervous system (PNS destruction during systemic vasculitides should be considered, due to its frequency and early occurrence in vasculitis progression. The first line treatment of non systematic VPNs is corticosteroid agents, but these drugs might worsen the VPNs or systemic vasculitis.

  9. Atomic approaches in metastable antiprotonic helium atoms. REPLY to 'analysis of the lifetimes and fractions of antiprotons trapped in metastable antiprotonic-helium states' by I. Shimamura and M. Kimura

    International Nuclear Information System (INIS)

    Yamazaki, Toshimitsu; Ohtsuki, Kazumasa.

    1994-08-01

    In the present note the authors clarify the purpose of YO and complement its essential points, thus showing that the criticisms of SK are inappropriate. The paper YO [1] was aimed at discussing some new aspects related to the metastability of hadronic helium atoms which had been discovered when negative kaons [2], negative pions [3] and antiprotons [4] were stopped in liquid helium. The delayed fraction, time spectrum shape and lifetimes were the observables. Further experimental studies are in progress [5], and as of today there is no successful explanation for these interesting phenomena. So, YO tried to give brief and rather qualitative estimates for the observations in an intuitive way, considering only the leading terms. The following problems are discussed in as simple a manner as possible, starting from the exotic-atom viewpoints of Condo [6] and Russell [7]: i)the atomic core polarization effect, ii)the structure and radiative lifetimes, iii)the non-statistical distribution of the angular momentum and an estimate of the delayed fraction, and iv)the isotope effect, though the title represents only i). To respond to the comments of SK, it is important to consider the correspondence between the atomic approach and the molecular approach for the metastable antiprotonic helium atom of Condo-Russell. We therefore begin this note with a discussion of this aspect. (author)

  10. The Bess Investigation of the Origin of Cosmic-ray Antiprotons and Search for Cosmological Antimatter

    Science.gov (United States)

    Mitchell, John; Yamamoto, Akira; Yoshimura, Koji; Makida, Yasuhiro; Matsuda, Shinya; Hasegawa, Masaya; Horikoshi, Atsushi; Tanaka,Ken-ichi; Suzuki, Junichi; Nishimura, Jun; hide

    2008-01-01

    The Balloon-borne Experiment with a Superconducting Spectrometer (BESS) collaboration has made precise measurements of the spectra of cosmic ray antiprotons and light nuclei and conducted a sensitive search for antinuclei. Ten BESS high-latitude flights, eight from Canada and two from Antarctica, span more than a Solar cycle between 1993 and 2007/2008. BESS measurements of low-energy antiprotons constrain candidate models for dark matter including the possible signature of primordial black hole evaporation. The stringent BESS measurements of antiprotons and the elemental and isotopic spectra of H and He provide strong constraints on models of cosmic-ray transport in the Galaxy and Solar System. BESS has also reported the first antideuterium upper limit. BESS employs a superconducting magnetic-rigity spectrometer with time-of-flight and aerogel Cherenkov detectors to identify incident particles by charge, charge sign, mass, and energy. The BESS-Polar long-duration instrument has reduced lower energy limit of 100 MeV (top of the atmosphere) to increase its sensitivity to possible primary antiproton sources. BESS-Polar II was rebuilt with extended magnet lifetime, improved detector and electronic performance, and greater data storage capacity. It was flown fro Antarctica December 2007-January 2008, recording about 4.6 bission events during 24.5 days at float altitude with the magnet on. During the flight the influence of a high-speed stream in the Solar wind was observed. Details of the BESS-Polar II instrument and flight performance are reported elsewhere at this conference. The successful BESS-Polar II flight at Solar minimum is especially important. Most cosmic-ray antiprotons are secondary products of nuclear interactions of primary cosmic-ray nuclei with the interstellar gas, giving a spectrum that peaks at about 2 GeV and falls rapidly to higher and lower energies. However, BESS data taken in the previous Solar minimum show a small excess over secondary

  11. Investigation of the antiprotonic X-ray spectra of the isotopes 6Li, 7Li and 40Ca

    International Nuclear Information System (INIS)

    Barth, H.

    1987-04-01

    With the commissioning of the Low-Energy Antiproton Ring (LEAR) at CERN in Geneva a high intensity, high purity antiproton beam became available, enabling precision measurements of antiprotonic X-ray spectra to be carried out. Besides informations about properties of the elementary particle antiproton itself, as for example its mass and its magnetic moment, such measurements provide informations about the strong-interaction potential between antiproton and nucleus at very low energies, which, in turn, can be derived from the elementary antinucleon-nucleon interaction by using microscopic models. This work investigates the antiprotonic X-ray spectra of the isotopes 6 Li, 7 Li and 40 Ca. The data were taken during the experiment PS176 at LEAR. The strong interaction between antiproton and nucleus leads to an energy shift ε and an absorption width Γ of the lower level of the last observable transition and also to intensity reductions, which can be converted to an absorption width for the upper level. For the isotopes 6 Li, 7 Li and 40 Ca the following results were obtained: 6 Li: ε(2p)=(-215±25) eV, Γ(2p)=(660±170) eV and Γ(3d)=(135±16) meV, 7 Li ε(2p)=(-265±20) eV, Γ(2p)=(690±170) eV and Γ(3d)=(129±13) meV, 40 Ca: ε(4f)=(-1060±130) eV, Γ(4f)=(3670±600) eV and Γ(5g)=(34.9±3.3) eV. The results are in fair agreement with theoretical calculations, at the same time showing up the limits of present understanding of antiproton-nucleus interaction. Particularly the spin-orbit part of the strong interaction seems to play a nonnegligible role. (orig.) [de

  12. Determination of the antiproton-to-electron mass ratio by precision laser spectroscopy of $\\overline{p}He^{+}$

    CERN Document Server

    Hori, M; Eades, John; Gomikawa, K; Hayano, R S; Ono, N; Pirkl, Werner; Widmann, E; Torii, H A; Juhász, B; Barna, D; Horváth, D

    2006-01-01

    A femtosecond optical frequency comb and continuous-wave pulse- amplified laser were used to measure 12 transition frequencies of antiprotonic helium to fractional precisions of (9-16) 10/sup -9lifetimes hitherto unaccessible to our precision laser spectroscopy method. Comparisons with three-body QED calculations yielded an antiproton-to-electron mass ratio of M/sub pmacron//m/sub e/=1836.152 674(5).

  13. PLANNING NATIONAL RADIOTHERAPY SERVICES

    Directory of Open Access Journals (Sweden)

    Eduardo eRosenblatt

    2014-11-01

    Full Text Available Countries, states and island nations often need forward planning of their radiotherapy services driven by different motives. Countries without radiotherapy services sponsor patients to receive radiotherapy abroad. They often engage professionals for a feasibility study in order to establish whether it would be more cost-beneficial to establish a radiotherapy facility. Countries where radiotherapy services have developed without any central planning, find themselves in situations where many of the available centres are private and thus inaccessible for a majority of patients with limited resources. Government may decide to plan ahead when a significant exodus of cancer patients travel to another country for treatment, thus exposing the failure of the country to provide this medical service for its citizens. In developed countries the trigger has been the existence of highly visible waiting lists for radiotherapy revealing a shortage of radiotherapy equipment.This paper suggests that there should be a systematic and comprehensive process of long-term planning of radiotherapy services at the national level, taking into account the regulatory infrastructure for radiation protection, planning of centres, equipment, staff, education pr

  14. Effect of radiotherapy on the natural killer (NK)-cell activity of cancer patients

    International Nuclear Information System (INIS)

    McGinnes, K.; Florence, J.; Penny, R.

    1987-01-01

    The aim of this study was to determine the effect of radiotherapy on peripheral blood natural killer (NK)-cell number and activity in 15 patients with cancer, prior to the commencement and at the completion of radiotherapy. The following observations were made. Prior to radiotherapy NK activity could not be correlated with the stage of malignancy. In all patients with advanced disease and with subnormal baseline NK activity, the outcome of radiotherapy was unfavorable. Following radiotherapy to sites including the mediastinum, patients had decreased NK activity compared with those receiving treatment to other sites. This decrease was not related to the dose of radiotherapy or stage of malignancy. The tumor response was favorable in most patients whose NK activity decreased as a result of radiotherapy. The decrease in NK activity may be associated with a decrease in the percentage of NK (N901) cells in the peripheral blood. The reduction in NK activity in those patients receiving mediastinal irradiation may be due to the large volume of blood which transits the field, so that the NK cells, or their more radiosensitive precursors, may be damaged and/or differentiation inhibited. Thus, these new observations show that radiotherapy does indeed affect the NK activity in cancer patients predominantly when the irradiation site includes the mediastinum

  15. To understand radiotherapy

    International Nuclear Information System (INIS)

    2009-01-01

    Dealing with the use of radiotherapy for adults, this guide indicates when a radiotherapy is suggested, how it acts, how the treatment is chosen, which are the professionals involved. It describes how an external radiotherapy takes place and its various techniques, the different types of side effects (general, specific to the treated zone, late effects). It indicates which organs can be treated by curie-therapy, the different curie-therapy treatment modalities, how a curie-therapy takes place and which are its side effects. It outlines how to better cope with radiotherapy (how to be supported, the important role of relatives, everyday life questions, rights). It indicates and comments the different measures adopted for the safety and quality of radiotherapy

  16. Donating Peripheral Blood Stem Cells

    Science.gov (United States)

    ... Print this page My Cart Donating peripheral blood stem cells Peripheral blood stem cell (PBSC) donation is a nonsurgical procedure to collect ... Donating bone marrow Donor experiences videos Peripheral blood stem cell (PBSC) donation is one of two methods of ...

  17. Peripheral Neuropathy: Symptoms and Signs

    Science.gov (United States)

    ... Utah Research News Make a Difference Symptoms of Peripheral Neuropathy Print This Page Peripheral Neuropathy symptoms usually start ... more slowly over many years. The symptoms of peripheral neuropathy often include: A sensation of wearing an invisible “ ...

  18. 132 ns Bunch Spacing in the Tevatron Proton-Antiproton Collider

    International Nuclear Information System (INIS)

    Holmes, S.D.; Holt, J.; Johnstone, J.A.; Marriner, J.; Martens, M.; McGinnis, D.

    1994-12-01

    Following completion of the Fermilab Main Injector it is expected that the Tevatron proton-antiproton collider will be operating at a luminosity in excess of 5x10 3l cm -2 with 36 proton and antiproton bunches spaced at 396 nsec. At this luminosity, each of the experimental detectors will see approximately 1.3 interactions per crossing. Potential improvements to the collider low beta and rf systems could push the luminosity beyond 10x10 3l cm -2 sec -1 , resulting in more than three interactions per crossing if the bunch separation is left unchanged. This paper discusses issues related to moving to ∼100 bunch operation, with bunch spacings of 132 nsec, in the Tevatron. Specific scenarios and associated hardware requirements are described

  19. Production of hyperfragments by antiprotons at rest annihilating on nuclei in nuclear photoemulsion

    International Nuclear Information System (INIS)

    Batusov, Yu.A.; Bunyatov, S.A.; Pontecorvo, G.B.

    1992-01-01

    Events have been observed, for the first time, of the production, departure and mesonic decay of the light hyperfragments Λ 3 H and Λ 4 H in the annihilation on the light (C, N, O, S)-nuclei of antiprotons stopping in nuclear photoemulsion. The lower limit of the production probability of Λ 3 H and Λ 4 H hyperfragments per single antiproton stopping in nuclear photoemulsion has been determined to be (6.1±3.5)x10 -4 . The charge exchange, on nucleons of the residual nucleus, of K - -mesons resulting from the annihilation process has been demonstrated to be the most probable mechanism of hyperfragment production. 17 refs.; 9 figs

  20. Investigation of silicon sensors for their use as antiproton annihilation detectors

    Energy Technology Data Exchange (ETDEWEB)

    Pacifico, N., E-mail: nicola.pacifico@cern.ch [University of Bergen, Institute of Physics and Technology, Allégaten 55, 5007 Bergen (Norway); Aghion, S. [Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milano (Italy); Istituto Nazionale di Fisica Nucleare, Sez. di Milano, Via Celoria 16, 20133 Milano (Italy); Ahlén, O. [European Organisation for Nuclear Research, Physics Department, 1211 Geneva 23 (Switzerland); Belov, A.S. [Institute for Nuclear Research of the Russian Academy of Sciences, Moscow 117312 (Russian Federation); Bonomi, G. [University of Brescia, Department of Mechanical and Industrial Engineering, Via Branze 38, 25133 Brescia (Italy); Istituto Nazionale di Fisica Nucleare, Sez. di Pavia, Via Agostino Bassi 6, 27100 Pavia (Italy); Bräunig, P. [Kirchhoff Institute for Physics, Im Neuenheimer Feld 227, 69120 Heidelberg (Germany); Bremer, J. [European Organisation for Nuclear Research, Physics Department, 1211 Geneva 23 (Switzerland); Brusa, R.S. [Department of Physics, University of Trento, via Sommarive 14, 38123 Povo, Trento (Italy); INFN-TIFPA, via Sommarive 14, 38123 Povo, Trento (Italy); Burghart, G. [European Organisation for Nuclear Research, Physics Department, 1211 Geneva 23 (Switzerland); Cabaret, L. [Laboratoire Aimé Cotton, CNRS, Université Paris Sud, ENS Cachan, Bâtiment 505, Campus d' Orsay, 91405 Orsay Cedex (France); Caccia, M. [University of Insubria, Dipartimento di Scienza ed Alta Tecnologia, via Valleggio 11, Como (Italy); Canali, C. [University of Zurich, Physics Institute, Winterthurerstrasse 190, 8057 Zurich (Switzerland); Caravita, R. [Istituto Nazionale di Fisica Nucleare, Sez. di Genova, Via Dodecaneso 33, 16146 Genova (Italy); University of Genoa, Department of Physics, Via Dodecaneso 33, 16146 Genova (Italy); Castelli, F. [University of Milano, Department of Physics, Via Celoria 16, 20133 Milano (Italy); and others

    2014-11-21

    We present here a new application of silicon sensors aimed at the direct detection of antinucleons annihilations taking place inside the sensor's volume. Such detectors are interesting particularly for the measurement of antimatter properties and will be used as part of the gravity measurement module in the AEg{sup ¯}IS experiment at the CERN Antiproton Decelerator. One of the goals of the AEg{sup ¯}IS experiment is to measure the gravitational acceleration of antihydrogen with 1% precision. Three different silicon sensor geometries have been tested with an antiproton beam to investigate their properties as annihilation detection devices: strip planar, 3D pixels and monolithic pixel planar. In all cases we were successfully detecting annihilations taking place in the sensor and we were able to make a first characterization of the clusters and tracks.

  1. A Cryogenic Current Comparator for the Low Energy Antiproton Facilities at CERN

    CERN Document Server

    Fernandes, M; Welsch, CP

    2014-01-01

    Several laboratories have shown the potential of using Superconducting QUantum Interference Device (SQUID) magnetometers together with superconductor magnetic shields to measure beam current intensities in the submicro-Ampere regime. CERN, in collaboration with GSI, Jena university and Helmholtz Institute Jena, is currently working on developing an improved version of such a current monitor for the Antiproton Decelerator (AD) and Extra Low ENergy Antiproton (ELENA) rings at CERN, aiming for better current resolution and overall system availability. This contribution will present the current design, including theoretical estimation of the current resolution; stability limits of SQUID systems and adaptation of the coupling circuit to the AD beam parameters; the analysis of thermal and mechanical cryostat modes.

  2. Dynamic studies of multiple configurations of CERN's Antiproton Decelerator Target core under proton beam impact

    CERN Document Server

    AUTHOR|(CDS)2248381

    Antiprotons, like many other exotic particles, are produced by impacting high energy proton beams onto fixed targets. At the European Organization for Nuclear Research (CERN), this is done in the Antiproton Decelerator (AD) Facility. The engineering challenges related to the design of an optimal configuration of the AD-Target system derive from the extremely high energy depositions reached in the very thin target core as a consequence of each proton beam impact. A new target design is foreseen for operation after 2021, triggering multiple R&D activities since 2013 for this purpose. The goal of the present Master Thesis is to complement these activities with analytical and numerical calculations, delving into the phenomena associated to the dynamic response of the target core. In this context, two main studies have been carried out. First, the experimental data observed in targets subjected to low intensity proton pulses was cross-checked with analytical and computational methods for modal analysis, applie...

  3. Antiproton cross-field diffusion in antihydrogen production experiments due to anisotropic binary interactions

    International Nuclear Information System (INIS)

    Ordonez, C.A.; Correa, J.R.

    2007-01-01

    Collisional processes in electrostatic ion storage rings and reflecting-beam-type electrostatic ion traps can be associated with anisotropic binary interactions, because shielding of the Coulomb interactions may not take place in one or more dimensions. Collisional scattering theory has recently been developed for describing the velocity-space scattering processes in such systems [J.R. Correa, Y. Chang, C.A. Ordonez, Phys. Plasmas 12 (2005) 084505]. The theory is extended to enable the effect of a magnetic field to be included. The theory is intended to be applicable, for example, to antiproton scattering within nested Penning traps that are used to produce antihydrogen [M. Amoretti et al., Nature 419 (2002) 456; G. Gabrielse et al., Phys. Rev. Lett. 89 (2002) 213401]. The theory is applied for considering the cross-magnetic-field diffusion of the antiprotons

  4. Carbon filament beam profile monitor for high energy proton-antiproton storage rings

    International Nuclear Information System (INIS)

    Evans, L.R.; Shafer, R.E.

    1979-01-01

    The measurement of the evolution of the transverse profile of the stored beams in high energy proton storage rings such as the p-anti p colliders at CERN and at FNAL is of considerable importance. In the present note, a simple monitor is discussed which will allow almost non-destructive measurement of the profile of each individual proton and antiproton bunch separately. It is based on the flying wire technique first used at CEA and more recently at the CPS. A fine carbon filament is passed quickly through the beam, acting as a target for secondary particle production. The flux of secondary particles is measured by two scintillator telescopes, one for protons and one for antiprotons, having an angular acceptance between 30 and 100 mrad. Measurements of secondary particle production performed at FNAL in this angular range show that a very respectable flux can be expected

  5. Anti- and Hypermatter Research at the Facility for Antiproton and Ion Research FAIR

    International Nuclear Information System (INIS)

    Steinheimer, J; Xu, Z; Gudima, K; Botvina, A; Mishustin, I; Bleicher, M; Stöcker, H

    2012-01-01

    Within the next six years, the Facility for Antiproton and Ion Research (FAIR) is built adjacent to the existing accelerator complex of the GSI Helmholtz Center for Heavy Ion Research at Darmstadt, Germany. Thus, the current research goals and the technical possibilities are substantially expanded. With its worldwide unique accelerator and experimental facilities, FAIR will provide a wide range of unprecedented fore-front research in the fields of hadron, nuclear, atomic, plasma physics and applied sciences which are summarized in this article. As an example this article presents research efforts on strangeness at FAIR using heavy ion collisions, exotic nuclei from fragmentation and antiprotons to tackle various topics in this area. In particular, the creation of hypernuclei and antimatter is investigated.

  6. The international Facility for Antiproton and Ion Research FAIR: Challenges and Opportunities

    International Nuclear Information System (INIS)

    Hoehne, C.

    2009-01-01

    The status of FAIR, the planned 'Facility for Antiproton and Ion Research', is presented in this contribution. FAIR will be a world unique particle accelerator facility to be built as a joint project by - as of today - 16 member countries. FAIR, which is planned for construction adjacent to the GSI site in Germany, is an integrated system of particle accelerators, 2 superconducting synchrotrons and 8 storage rings, which will provide high energy and high intensity beams of ions from hydrogen to uranium with unprecedented quality and in full parallel mode. In addition highest luminosity secondary beams of rare isotopes and beams of antiprotons will be available. FAIR will combine physics research topics from different communities, i.e. nuclear physics, hadron physics, heavy-ion physics, plasma physics, atomic physics and accelerator development. Details of FAIR and the physics projects will be presented in this contribution.

  7. Suppression of propagating TE modes in the FNAL antiproton source stochastic beam cooling system

    International Nuclear Information System (INIS)

    Barry, W.C.

    1985-05-01

    A method of attenuating the propagation of waveguide modes in the stochastic cooling array beam pipes to be utilized in the accumulator and debuncher rings of the Fermilab antiproton source is described. The attenuation method treated involves lining the vertical walls of the beam pipes with a ferrimagnetic material. The general solution for propagation in a nonhomogeneously loaded waveguide is presented along with numerical results specific to the antiproton source beam cooling system. Also described is a broadband, automated technique for the simultaneous measurement of complex μ and epsilon developed to aid in the characterization of different ferrite materials. Permittivity and permeability data for a typical ferrite are presented along with a discussion of the effects of these parameters on waveguide mode attenuation in the ferrite lined beam pipes

  8. Antiproton production in heavy-ion collisions at energies below the threshold

    International Nuclear Information System (INIS)

    Schroeter, A.

    1993-08-01

    In the framework of this thesis the antiproton production in heavy ion collisions at projectile energies far below the threshold for anti p production in nucleon-nucleon collisions (5.63 GeV/u) was studied. A suited detection apparature was developed and constructed at the fragment separator-magnet spectrometer at the Society for Heavy Ion Research (GSI). For the identification of the antiprotons the momentum of the particles emitted in beam direction was measured and their velocity multiple-redundantly determined by means of time-of-flight measurements and threshold Cherenkov detectors. By this way the antiprotons could be in spite of low anti p production cross sections and high production rates for lighter particles (R anti p: R K - -:R π - -∼1:5*10 3 :10 7 ) background-freely determined. By this experiment for Ne+NaF, Cu, Sn, and Bi as well ass Ni+Ni collisions at incident energies between 1.6 GeV/u and 2.0 GeV/u production cross sections for antiprotons in the momentum range between 1.0 GeV/c and 2.2 GeV/c and for kaons and pions between 0.5 GeV/c and 2.8 GeV/c were measured, in order to study the influence of collisional-system size, incident energy, and secondary-particle momentum on the production probabilities and to contribute in comparison with the prognoses of theoretical models to the explanation of the particle production mechanisms. (HSI)

  9. Study of relativistic heavy-ion interactions and antiproton annihilation data

    International Nuclear Information System (INIS)

    Ghosh, D.; Roy, J.; Sengupta, R.

    1986-01-01

    The characteristics of 12 C-AgBr interaction at 4.5-GeV · c -1 · nucleon -1 incident momentum are studied by means of the photoemulsion technique, to search for shock-wave phenomena. The angular distributions indicate an anisotropic process in the nuclear matter. The results are compared with the antiproton -AgBr reaction observations of Breivik et al. (1983) at 1.4 GeV · c -1

  10. Antiproton interaction with 4He as a test of GUT cosmology

    International Nuclear Information System (INIS)

    Chechetkin, V.M.; Khlopov, M.Yu.; Zeldovich, Ya.B.

    1982-01-01

    A new possibility of checking some GUT models is suggested, basing on the analysis of their cosmological consequences and the experimental study of the anti p 4 He interaction. The study of annihilation of antiprotons with 4 He may provide limits on the possible amount of antimatter in the early Universe, limits on the probability of formation of primordial black holes and restrictions on the GUT parameters determining the properties of domains of antimatter

  11. Using the circulating beam in the Fermilab antiproton accumulator for experiments

    International Nuclear Information System (INIS)

    MacLachlan, J.A.

    1988-01-01

    The Fermilab Accumulator is a storage ring optimized for stacking and stochastic cooling 8 GeV antiprotons for the Tevatron collider. Minor modifications have been made to provide for beam in the energy range 8.0-2.9 GeV of luminosity /approximately/10 31 cm -2 s/sup - 1/ with a hydrogen jet internal target. Experience to date consists of machine studies and detector engineering run with protons. 7 refs

  12. Experimental and computational study of the injection of antiprotons into a positron plasma for antihydrogen production

    DEFF Research Database (Denmark)

    Amole, C.; Ashkezari, M.D.; Baquero-Ruiz, M.

    2013-01-01

    One of the goals of synthesizing and trapping antihydrogen is to study the validity of charge-parity-time symmetry through precision spectroscopy on the anti-atoms, but the trapping yield achieved in recent experiments must be significantly improved before this can be realized. Antihydrogen atoms...... and upcoming antihydrogen experiments, and the latter scheme is seen to offer significant improvement in trapping yield as the number of available antiprotons increases....

  13. Formation and decay of nuclei heated with high-energy antiprotons

    CERN Document Server

    Lott, B; Eades, J.; Egidy, T.v.; Figuera, P.; Fuchs, H.; Galin, J.; Gulda, K.; Goldenbaum, F.; Hilscher, D.; Jahnke, U.; Jastrzebski, J.; Kurcewicz, W.; Morjean, M.; Pausch, G.; Péghaire, A.; Pienkowski, L.; Polster, D.; Proschitzki, S.; Quednau, B.; Rossner, H.; Schmid, S.; Schmid, W.; Ziem, P.

    1999-01-01

    The decay of nuclei excited via the annihilation of 1.2 GeV antiprotons has been investigated. Thanks to the ability to determine the excitation energy, E sup * , for all events, largely irrespective of their mass partitions, the probabilities of the different channels at play could be estimated as a function of E sup *. The data show the prevalence of fission and evaporation up to E sup * = 4 MeV/nucleon, with no hint of a transition towards multifragmentation.

  14. The GSI plans for an international accelerator facility for beams of ions and antiprotons

    International Nuclear Information System (INIS)

    Suemmerer, K.

    2003-01-01

    GSI proposes to build a next-generation facility for research with relativistic beams of ions and antiprotons. This facility allows a broad range of topics in nuclear and astrophysics, plasma and atomic physics to be addressed. The topic most interesting in the context of this conference is physics with high-intensity beams of exotic nuclei. In addition, a short overview of the opportunities in the other fields of nuclear physics is given

  15. Cosmic-ray antiprotons as a probe of a photino-dominated universe

    Science.gov (United States)

    Silk, J.; Srednicki, M.

    1984-01-01

    Observational tests of the hypothesis that the universe is flat and dominated by dark matter in the form of massive photinos include the production of significant fluxes of cosmic rays and gamma rays in our galactic halo. Specification of the cosmological photino density and the masses of scalar quarks and leptons determines the present annihilation rate. The predicted number of low-energy cosmic-ray antiprotons is comparable to the observed flux.

  16. Proton - antiproton annihilations to φφ mesons: results from JETSET at LEAR

    Science.gov (United States)

    Bertolotto, L.; Buzzo, A.; Debevec, P. T.; Drijard, D.; Easo, S.; Eisenstein, R. A.; Evangelista, C.; Eyrich, W.; Fearnley, T.; Ferro-Luzzi, M.; Franz, J.; Geyer, R.; Hamann, N.; Harris, Ph.; Hertzog, D. W.; Hughes, S. A.; Johansson, T.; Jones, R.; Kilian, K.; Kirsebom, K.; Klett, A.; Korsmo, H.; Lo Vetere, M.; Marinelli, M.; Moossburger, M.; Mouëllic, B.; Oelert, W.; Ohlsson, S.; Palano, A.; Passaggio, S.; Perreau, J. M.; Pia, M. G.; Pozzo, A.; Price, M.; Reimer, P. E.; Ritter, J.; Robutti, E.; Röhrich, K.; Rook, M.; Rössle, E.; Santroni, A.; Schmitt, H.; Steinkamp, O.; Stinzing, F.; Stugu, B.; Tscheulin, M.; Urban, H. J.; Wirth, H.; Zipse, H.; Jetset Collaboration

    1993-06-01

    The πp → φφ reaction has been studied in an internal target experiment at LEAR using antiprotons at various laboratory momenta spanning the region between 1 and 2 GeV/c (cms energies between 2.08 and 2.43 GeV). Cross sections have been measured at a total of 16 different energy settings over the above range. Preliminary cross sections are reported.

  17. Proton-antiproton annihilations to [phi][phi]mesons: results from JETSET at LEAR

    Energy Technology Data Exchange (ETDEWEB)

    Bertolotto, L.; Buzzo, A.; Devevec, P.T.; Drijard, D.; Easo, S.; Eisenstein, R.A.; Evangelista, C.; Eyrich, W.; Fearnley, T.; Ferro-Luzzi, M.; Franz, J.; Geyer, R.; Hamann, N.; Harris, P.; Hertzog, D.W.; Hughes, S.A.; Johansson, T.; Jones, R.; Kilian, K.; Kirsebom, K.; Klett, A.; Korsmo, H.; Lo Vetere, M.; Marinelli, M.; Moossburger, M.; Mouellic, B.; Oelert, W.; Ohlsson, S.; Palano, A.; Passaggio, S.; Perreau, J.M.; Pia, M.G.; Pozzo, A.; Price, M.; Reimer, P.E.; Ritter, J.; Robutti, E.; Roehrich, K.; Rook, M.; Roessle, E.; Santroni, A.; Schmitt, H.; Steinkamp, O.; Stinzing, F.; Stugu, B.; Tscheulin, M.; Urban, H.J.; Wirth, H.; Zipse, H. (Istituto Nazionale di Fisica Nucleare, Genoa (Italy) Genoa Univ. (Italy) Univ. of Illinois, Urbana-Champaign (United States) European Organization for Nuclear Research (CERN), Geneva (Switzerland) Istituto Nazionale di Fisica Nucleare, Bari (Italy) Bari Univ. (Italy) Physikalisches Institut, Erlangen Univ. (Germany) Fakultaet fuer Physik, Univ. Freib; JETSET Collaboration

    1993-06-07

    The [pi]p[yields][phi][phi] reaction has been studied in an internal target experiment at LEAR using antiprotons at various laboratory momenta spanning the region between 1 and 2 GeV/c (cms energies between 2.08 and 2.43 GeV). Cross sections have been measured at a total of 16 different energy settings over the above range. Preliminary cross sections are reported. (orig.)

  18. Proton-antiproton annihilations to φφmesons: results from JETSET at LEAR

    International Nuclear Information System (INIS)

    Bertolotto, L.; Buzzo, A.; Devevec, P.T.; Drijard, D.; Easo, S.; Eisenstein, R.A.; Evangelista, C.; Eyrich, W.; Fearnley, T.; Ferro-Luzzi, M.; Franz, J.; Geyer, R.; Hamann, N.; Harris, P.; Hertzog, D.W.; Hughes, S.A.; Johansson, T.; Jones, R.; Kilian, K.; Kirsebom, K.; Klett, A.; Korsmo, H.; Lo Vetere, M.; Marinelli, M.; Moossburger, M.; Mouellic, B.; Oelert, W.; Ohlsson, S.; Palano, A.; Passaggio, S.; Perreau, J.M.; Pia, M.G.; Pozzo, A.; Price, M.; Reimer, P.E.; Ritter, J.; Robutti, E.; Roehrich, K.; Rook, M.; Roessle, E.; Santroni, A.; Schmitt, H.; Steinkamp, O.; Stinzing, F.; Stugu, B.; Tscheulin, M.; Urban, H.J.; Wirth, H.; Zipse, H.

    1993-01-01

    The πp→φφ reaction has been studied in an internal target experiment at LEAR using antiprotons at various laboratory momenta spanning the region between 1 and 2 GeV/c (cms energies between 2.08 and 2.43 GeV). Cross sections have been measured at a total of 16 different energy settings over the above range. Preliminary cross sections are reported. (orig.)

  19. Simplified dark matter models in the light of AMS-02 antiproton data

    International Nuclear Information System (INIS)

    Li, Tong

    2017-01-01

    In this work we perform an analysis of the recent AMS-02 antiproton flux and the antiproton-to-proton ratio in the framework of simplified dark matter models. To predict the AMS-02 observables we adopt the propagation and injection parameters determined by the observed fluxes of nuclei. We assume that the dark matter particle is a Dirac fermionic dark matter, with leptophobic pseudoscalar or axialvector mediator that couples only to Standard Model quarks and dark matter particles. We find that the AMS-02 observations are consistent with the dark matter framework within the uncertainties. The antiproton data prefer a dark matter (mediator) mass in the 700 GeV–5 TeV region for the annihilation with pseudoscalar mediator and greater than 700 GeV (200 GeV–1 TeV) for the annihilation with axialvector mediator, respectively, at about 68% confidence level. The AMS-02 data require an effective dark matter annihilation cross section in the region of 1×10 −25 –1×10 −24 (1×10 −25 –4×10 −24 ) cm 3 /s for the simplified model with pseudoscalar (axialvector) mediator. The constraints from the LHC and Fermi-LAT are also discussed.

  20. Heavy flavour production and heavy flavour mixing at the CERN proton-antiproton collider

    International Nuclear Information System (INIS)

    Eijk, B. van.

    1987-01-01

    In this thesis some results of the proton-antiproton-collision experiment UA1 with the CERN Super Proton-Antiproton Synchrotron are presented and interpreted. Ch. 1 contians a general introduction to the physics motivations behind the proton-antiproton-collider project, a brief description of the CERN facilities and a summary of collider and UA1 physics achievements. Furthermore the concept of studying heavy flavours via their weak decays into muons is introduced. Ch. 2 gives a brief overview of the UA1 experimental set-up, while those parts of the detector that are relevant for the analysis, presented in this thesis, is discussed in some more detail. Ch. 3 contains a short introduction to, and motivation for the use of Monte Carlo techniques in event simulations, while Ch. 4 describes the framework of the recently developed 'EUROJET' event generator. In Ch. 5 a treatment is given of the theoretical background and concepts like 'quark-mixing' and 'CP-violation' are explained, also other useful definitions and formulae are introduced on which the later analysis of the same-sign to opposite-sign dimuon ratio is built. Data collection and event reconstruction is the subject of Ch. 6, while a detailed comparison between the theoretical models and experimentally obtained distributions is given in Ch. 7. Finally, in Ch. 8 some concluding remarks are made. 182 refs.; 81 figs.; 9 tabs

  1. A measurement of the gravitational acceleration of the anti-proton

    CERN Document Server

    Holzscheiter, M H

    1990-01-01

    A fundamental experiment in gravity proposed by us, is the measurement of the gravitational force on antimatter. This measurement would constitute the first direct test of the Weak Equivalence Principle (WEP) for antimatter. The availability of low-energy antiprotons at CERN has made such an experiment feasible, and a proposal to carry out such a measurement has been accepted by the CERN Program Committee. We plan to use a time-of-flight technique similar to that pioneered by Fairbank and Witteborn in their measurement of the gravitational force on an electron. Very slow particles are launched into a vertical drift tube and the time-of-flight spectrum of these particles is recorded. This spectrum will exhibit a cut-off point directly related to the gravitational acceleration of the particles. Obtaining very slow antiprotons involves several stages of deceleration. Antiprotons from LEAR will be initially decelerated from 2 MeY to tens of kilovolts by passing them through a thin foil. After capture and cooling ...

  2. Application of high quality antiproton beam to study charmonium and exotics above DD-bar threshold

    International Nuclear Information System (INIS)

    Barabanov, M.Y.; Vodopyanov, A.S.

    2014-01-01

    The spectroscopy of charmonium and exotic states with hidden charm is discussed. It is a good testing tool for theories of strong interactions including QCD in both perturbative and non-perturbative regime, lattice QCD, potential models and phenomenological models. An elaborated analysis of charmonium and charmed hybrid spectrum is given, and attempts to interpret recent experimental data in the above DD-bar threshold region are considered. Experiments using antiproton beam take advantage of the intensive production of particle-antiparticle pairs in antiproton-proton annihilations. Experimental data from different collaboration are analyzed with special attention given to new states with hidden charm that were discovered recently. Some of these states can be interpreted as higher-laying S, P and D wave charmonium states. But much more data on different decay modes are needed before firmer conclusions can be made. These data can be derived directly from the experiments using high quality antiproton beam with momentum up to 15 GeV/c. (authors)

  3. Simplified dark matter models in the light of AMS-02 antiproton data

    Energy Technology Data Exchange (ETDEWEB)

    Li, Tong [ARC Centre of Excellence for Particle Physics at the Tera-scale,School of Physics and Astronomy, Monash University,Melbourne, Victoria 3800 (Australia)

    2017-04-19

    In this work we perform an analysis of the recent AMS-02 antiproton flux and the antiproton-to-proton ratio in the framework of simplified dark matter models. To predict the AMS-02 observables we adopt the propagation and injection parameters determined by the observed fluxes of nuclei. We assume that the dark matter particle is a Dirac fermionic dark matter, with leptophobic pseudoscalar or axialvector mediator that couples only to Standard Model quarks and dark matter particles. We find that the AMS-02 observations are consistent with the dark matter framework within the uncertainties. The antiproton data prefer a dark matter (mediator) mass in the 700 GeV–5 TeV region for the annihilation with pseudoscalar mediator and greater than 700 GeV (200 GeV–1 TeV) for the annihilation with axialvector mediator, respectively, at about 68% confidence level. The AMS-02 data require an effective dark matter annihilation cross section in the region of 1×10{sup −25}–1×10{sup −24} (1×10{sup −25}–4×10{sup −24}) cm{sup 3}/s for the simplified model with pseudoscalar (axialvector) mediator. The constraints from the LHC and Fermi-LAT are also discussed.

  4. Measurements of Wake-Riding Electrons in Antiproton-Carbon-Foil Collisions

    CERN Multimedia

    2002-01-01

    When a charged particle passes through dielectric media, e.g. a thin carbon foil, a ``wake'' is induced. The characteristic wake-potential shows an oscillatory behaviour, with a wavelength of about $ 2 \\pi v _{p} / \\omega _{p} _{l} $ where $ v _{p} $ is the projectile velocity and $ \\omega _{p} _{l} $ the plasmon energy of the target. This induced wake potential is superimposed on the Coulomb potential of the projectile, the latter leading to a pronounced ``cusp'' of electrons leaving the solid at $ v _{e} app v _{p} $ for positively charged projectiles in the MeV region. Correspondingly, an ``anti-cusp'' is expected for antiprotons. \\\\ \\\\ In the solid, the wake-potential leads to an attractive force on electrons, and a dynamic electronic state is predicted both for proton and antiproton projectiles. In the solid, the wake-riding electrons are travelling with the projectile speed $ v _{p} $ Upon exit of the foil, the electron released from the wake-riding state of an antiproton will suddenly find itself in th...

  5. Elementary design of a 30 TeV on 30 TeV proton antiproton collider

    International Nuclear Information System (INIS)

    Kondo, Takahiko

    1984-01-01

    A crude conceptual design was made for a 30TeV on 30TeV antiproton-proton collider. The choice of energy and antiproton-proton (instead of PP) are somewhat arbitrary. The basic parameters of the main ring are listed in a table; the bending radius, ring radius and circumference are 11.1km, 14.4km, and 90.6km, respectively; 7680 dipole magnets with maximum field of 9 Tesla; 1280 quadrupole magnets with maximum gradient of 200Tesla/m. The development of high-field, low-heat loss dipoles and quadrupoles are essential, together with the consideration for their mass production method. On the other hand, the possibility of obtaining antiproton-proton luminosity exceeding 10 32 /cm 2 sec is suggested without any fundamental limitation. With such high luminosity, however, it should be pointed out that particle detectors must face their limitation due to extremely high rate, high multiplicity interaction, requiring large steps of detector research and development efforts. (Aoki, K.)

  6. Unified interpretation of cosmic-ray nuclei and antiproton recent measurements

    International Nuclear Information System (INIS)

    Di Bernardo, Giuseppe; Gaggero, Daniele; Evoli, Carmelo; Grasso, Dario; Maccione, Luca

    2009-09-01

    We use our numerical code, DRAGON, to study the implications and the impact of recent CREAM and PAMELA data on our knowledge of the propagation properties of cosmic ray nuclei with energy >or similar 1 GeV/n in the Galaxy. We will show that B/C (as well as N/O and C/O) and anti p/p data (especially including recent PAMELA results) can consistently be matched within a unique diffusion-reacceleration model. The requirement that light nuclei and anti p data are both reproduced within experimental uncertainties places stringent limits on suitable propagation parameters. In particular, we find the allowed range of the diffusion coefficient spectral index to be 0.38 A ≅15 kms -1 ) is allowed. Furthermore, we do not need to introduce any ad hoc break in the injection spectrum of primary cosmic rays. If antiproton data are not used to constrain the propagation parameters, a larger set of models is allowed. In this case, we determine which combinations of the relevant parameters maximize and minimize the antiproton flux under the condition of still fitting light nuclei data at 95% C.L. These models may then be used to constrain a possible extra antiproton component arising from astrophysical or exotic sources (e.g. dark matter annihilation or decay). (orig.)

  7. Peripheral Ulcerative Keratitis

    Science.gov (United States)

    ... oval in shape. Diagnosis A doctor's evaluation Sometimes culture The diagnosis of peripheral ulcerative keratitis is suspected when the doctor sees the affected cornea in a person who also has a severe and/or long- ...

  8. Tumors of peripheral nerves

    International Nuclear Information System (INIS)

    Ho, Michael; Lutz, Amelie M.

    2017-01-01

    Differentiation between malignant and benign tumors of peripheral nerves in the early stages is challenging; however, due to the unfavorable prognosis of malignant tumors early identification is required. To show the possibilities for detection, differential diagnosis and clinical management of peripheral nerve tumors by imaging appearance in magnetic resonance (MR) neurography. Review of current literature available in PubMed and MEDLINE, supplemented by the authors' own observations in clinical practice. Although not pathognomonic, several imaging features have been reported for a differentiation between distinct peripheral nerve tumors. The use of MR neurography enables detection and initial differential diagnosis in tumors of peripheral nerves. Furthermore, it plays an important role in clinical follow-up, targeted biopsy and surgical planning. (orig.) [de

  9. Historical review of radiotherapy

    International Nuclear Information System (INIS)

    Onai, Yoshio

    1993-01-01

    The techniques of radiotherapy have been improved by development of particle accelerators, radionuclides and computers. This paper presents a historical review of the physical and technical aspects of radiotherapy in Japan. Changes in the kinds of radiation, such as X-rays, gamma rays, electrons, neutrons and protons used for external radiotherapy, and the equipment involved are described chronologically, and historical changes in the quality of radiotherapy apparatus are outlined. Patient data acquisition equipment, such as X-ray simulator and X-ray CT, beam modifying devices, patient setup devices, and devices to verify treatment fields and patient doses are reviewed historically. Radiation sources for brachytherapy and internal radiotherapy, and remotely controlled afterloading systems are reviewed chronologically. Historical changes in methods to evaluate absorbed doses, dose monitor systems and beam data acquisition systems are outlined. Changes in methods of calculating dose distributions for external X-ray and electron therapy, brachytherapy and internal radiotherapy by unsealded radionuclides are described and calculation techniques for treatment planning system are reviewed. Annual figures in the numbers of radiotherapy equipment, such as telecobalt and telecesium units, linear accelerators, betatrons, microtrons, stereotactic gamma units, conformation radiotherapy units, remotely controlled afterloading systems, and associated equipment such as X-ray simulators and treatment planning systems are provided, as are changes in the number of accelerators by maximum X-ray energy and maximum electron energy, and in the number of licensed hospitals and clinics using small sealed sources. Changes in techniques of external radiotherapy and brachytherapy are described briefly from the point of view of dose distributions. (author)

  10. Radiological incidents in radiotherapy

    International Nuclear Information System (INIS)

    Hobzova, L.; Novotny, J.

    2008-01-01

    In many countries a reporting system of radiological incidents to national regulatory body exists and providers of radiotherapy treatment are obliged to report all major and/or in some countries all incidents occurring in institution. State Office for Nuclear Safety (SONS) is providing a systematic guidance for radiotherapy departments from 1997 by requiring inclusion of radiation safety problems into Quality assurance manual, which is the basic document for obtaining a license of SONS for handling with sources of ionizing radiation. For that purpose SONS also issued the recommendation 'Introduction of QA system for important sources in radiotherapy-radiological incidents' in which the radiological incidents are defined and the basic guidance for their classification (category A, B, C, D), investigation and reporting are given. At regular periods the SONS in co-operation with radiotherapy centers is making a survey of all radiological incidents occurring in institutions and it is presenting obtained information in synoptic communication (2003 Motolske dny, 2005 Novy Jicin). This presentation is another summary report of radiological incidents that occurred in our radiotherapy institutions during last 3 years. Emphasis is given not only to survey and statistics, but also to analysis of reasons of the radiological incidents and to their detection and prevention. Analyses of incidents in radiotherapy have led to a much broader understanding of incident causation. Information about the error should be shared as early as possible during or after investigation by all radiotherapy centers. Learning from incidents, errors and near misses should be a part of improvement of the QA system in institutions. Generally, it is recommended that all radiotherapy facilities should participate in the reporting, analyzing and learning system to facilitate the dissemination of knowledge throughout the whole country to prevent errors in radiotherapy.(authors)

  11. Measurement of asymmetries and differential cross sections in antiproton-proton elastic scattering at momenta between 497 and 1550 MeV/c

    International Nuclear Information System (INIS)

    Kunne, R.A.

    1988-01-01

    An intermediate energy antiproton proton (anti pp) elastic scattering experiment is described. The data comprise a set of 15 measurements of the differential cross section and the asymmetry between 497 and 1550 MeV/c antiproton momentum. The measurements were carried out using the high quality antiproton beam provided by the Low Energy Antiproton Ring (LEAR) at CERN. A conventional polarized target was used, consisting of pentanol. The motivation for the measurements is the study of the anti pp interaction by providing data on the spin observable A on in a momentum range where it has never been measured before. 56 refs.; 55 figs.; 40 tabs

  12. Promoting peripheral myelin repair

    OpenAIRE

    Zhou, Ye; Notterpek, Lucia

    2016-01-01

    Compared to the central nervous system (CNS), peripheral nerves have a remarkable ability to regenerate and remyelinate. This regenerative capacity to a large extent is dependent on and supported by Schwann cells, the myelin-forming glial cells of the peripheral nervous system (PNS). In a variety of paradigms, Schwann cells are critical in the removal of the degenerated tissue, which is followed by remyelination of newly-regenerated axons. This unique plasticity of Schwann cells has been the ...

  13. Radiotherapy indications - rectum cancer

    International Nuclear Information System (INIS)

    2009-05-01

    This document is addressed to oncologists radiotherapists and to any health professional concerned by rectum cancer treatment. Rectum cancer therapy is based on various technical procedures including surgery, radiotherapy and systemic treatments defined for each patient according to his clinical situation. This document precises the specific situations where radiotherapy can be employed. However, the radiotherapy decision must be taken with respect to other therapeutic alternatives. Such a decision must be validated and must be the object of a discussion in the framework of a pluri-disciplinary consultation. (J.S.)

  14. Conceptual Design Report. Antiproton - Proton Collider Upgrade 20 GeV Rings. Technical Components and Civil Construction May, 1988

    Energy Technology Data Exchange (ETDEWEB)

    None

    1988-05-01

    This report contains a description of the design and cost estimate of two new 20 GeV rings which will be required to support the upgrade of the Fermilab Collider with a luminosity goal of 5x10 31 cm-2s-1. The new rings include an antiproton post-accumulator, denoted the Antiproton Super Booster (ASB), and a proton post-booster, denoted the Proton Super Booster (PSB). The siting of the rings is shown in Figure I-1. Both rings are capable of operation at 20 GeV, eliminating the need for ever again injecting beam into the Main Ring below transition, and significantly enhancing Main Ring performance. The Antiproton Super Booster is designed to accept and accumulate up to 4x1012 antiprotons from the existing Antiproton Accumulator, and deliver them to the Main Ring at 20 GeV for acceleration and injection into the Collider. It is also designed to accept diluted antiprotons from the Main Ring at 20 GeV for recooling. The PSB accepts 8.9 GeV protons from the existing Booster and accelerates them to 20 GeV for injection into the Main Ring. The PSB is designed to operate at 5 Hz. The siting shown in Figure I-1 has the attractive feature that it removes all Main Ring injection hardware from the AO straight section, opening the possibility of installing a third proton-antiproton interaction region in the Tevatron Collider.

  15. Normal tissue tolerance to external beam radiation therapy: Peripheral nerves

    International Nuclear Information System (INIS)

    Henriques de Figueiredo, B.; Dejean, C.; Sargos, P.; Kantor, G.; Huchet, A.; Mamou, N.; Loiseau, H.

    2010-01-01

    Plexopathies and peripheral neuropathies appear progressively and with several years delay after radiotherapy. These lesions are observed principally after three clinical situations: supraclavicular and axillar irradiations for breast cancer, pelvic irradiations for various pathologies and limb irradiations for soft tissue sarcomas. Peripheral nerves and plexus (brachial and lumbosacral) are described as serial structures and are supposed to receive less than a given maximum dose linked to the occurrence of late injury. Literature data, mostly ancient, define the maximum tolerable dose to a threshold of 60 Gy and highlight also a great influence of fractionation and high fraction doses. For peripheral nerves, most frequent late effects are pain with significant differences of occurrence between 50 and 60 Gy. At last, associated pathologies (diabetes, vascular pathology, neuropathy) and associated treatments have probably to be taken into account as additional factors, which may increase the risk of these late radiation complications. (authors)

  16. Radiotherapy injuries in children

    International Nuclear Information System (INIS)

    Kalifa, G.; Bennet, J.; Couanet, D.; Masselot, J.

    1985-01-01

    Side effects of radiotherapy in pediatrics are reviewed including bone injuries and radio-induced bone tumors; nervous system injuries with emphasis on hypothalamus, pituitary gland, brain and spinal cord; lung, digestive system and urinary tract injuries [fr

  17. The metabolic radiotherapy

    International Nuclear Information System (INIS)

    Begon, F.; Gaci, M.

    1993-01-01

    In this article, the authors recall the principles of the metabolic radiotherapy and present these main applications in the treatment of thyroid cancers, hyperthyroidism, polycythemia, arthritis, bone metastases, adrenergic neoplasms. They also present the radioimmunotherapy

  18. Clinical practice of radiotherapy

    International Nuclear Information System (INIS)

    Tobias, J.S.

    1992-01-01

    After describing the recent advances in radiotherapy, this brief article presents in tabular form the changing indications for radiotherapy for tumours of the skin, head and neck, adult CNS, lung, thyroid, thymus, breast, female genital tract, soft tissue sarcoma, genitourinary tract, bone sarcoma, Hodgkin's disease, non-Hodgkin lymphoma, multiple myeloma, leukemia and paediatric malignancy. For each tumour type, information is provided for the radiosensitivity, the radiocurability, complications and five-year survival. Combined modality treatment is also briefly discussed. (UK)

  19. Nanoparticle-guided radiotherapy

    DEFF Research Database (Denmark)

    2012-01-01

    The present invention relates to a method and nano-sized particles for image guided radiotherapy (IGRT) of a target tissue. More specifically, the invention relates to nano-sized particles comprising X-ray-imaging contrast agents in solid form with the ability to block x-rays, allowing for simult...... for simultaneous or integrated external beam radiotherapy and imaging, e.g., using computed tomography (CT)....

  20. Clinical practice of radiotherapy

    International Nuclear Information System (INIS)

    Horiuchi, Junichi; Masaki, Norie; Onoyama, Yasuto

    1987-01-01

    This chapter presents in greater detail radiotherapy used in each clinical setting. The descriptions are given under the following sections: the tongue and oral cavity; the maxilla, larynx, and pharynx; brain tumors; the eyes and orbit; pediatric tumors; lung cancer; the esophagus; breast cancer; the abdominal digestive system; the urogenital system; the uterine cervix; the ovaries and vulva; bone and soft tissues; the skin; hematopoietic tumors; lymph node metastases; and radiotherapy as palliative treatment. (Namekawa, K.)

  1. Patients and radiotherapy

    International Nuclear Information System (INIS)

    Eardley, A.

    1986-01-01

    The results of interviews with thirty discharged patients who had undergone radical radiotherapy for cancer of the head and neck are presented. Patients were asked whether their side-effects had got worse or had stayed the same, what effect their side effects had had on eating and drinking and whether they had felt depressed during this period. Measures which could be taken to improve patients' experiences of radiotherapy are discussed. (U.K.)

  2. Radiotherapy and oral cancer

    Energy Technology Data Exchange (ETDEWEB)

    Sealy, R [Cape Town Univ. (South Africa). Dept. of Radiotherapy

    1982-08-01

    A general review article for the non-radiotherapist. The historical, physical and biological background is briefly reviewed. Mention is made of the effects of fraction size, hyperbaric oxygen, neutron beams and radiation sensitizers. The use of chemotherapy and radiotherapy is discussed, as well as the selection of patients for radiotherapy and the treatment of neck nodes. The author suggests a therapeutic approach to the various disease sites and finally reviews some of the literature on radiation caries and jaw necrosis.

  3. Extraction of ultra-low-energy antiprotons from the PS200 catching trap for atomic physics experiments

    International Nuclear Information System (INIS)

    Holzscheiter, M.H.

    1996-01-01

    Approximately one million antiprotons have been captured in a large-scale Penning trap at the low energy antiproton ring at CERN. Up to 65% of the captured antiprotons have subsequently been cooled by electron cooling to energies below 1 eV and have been stored up to one hour. This has opened new discussions of the possible use of ultra-low-energy antiprotons for nuclear, atomic, and gravitational physics. For most of these experiments it will be necessary to extract the antiprotons from the trap in the form of either a continuous beam or as a bunched beam, allowing the timing structure to be used for post-acceleration schemes or as a time tag for subsequent measurements. We have designed an extraction scheme to accomplish this and have tested portions of it using a smaller-scale Penning trap loaded with protons. First results in generating a time-correlated beam of particles from a Penning trap are presented. (orig.)

  4. Peripheral dose in photon beams from a linear accelerator with a multileaf collimator

    International Nuclear Information System (INIS)

    Lope Lope, R.; Lozano Flores, F.; Gracia Sorrosal, J.; Font Gomez, J.A.; Hernandez Vitoria, A.

    2001-01-01

    Radiation doses outside the radiotherapy treatment field are of radiation protection interest when anatomical structures with very low dose tolerances might be involved. One of the major sources of peripheral dose, scatter from secondary collimators, depends on the configuration of the collimator. In this study, peripheral dose was measured at two depths for 6 and 18 MV photons from a linac Primus (Siemens) with a multileaf collimator (MLC). Comparative measurements were made both with leaves and with the upper jaw positioned at the field edge near to the detector. Configuring the MLC leaves at the field edge yielded a reduction in peripheral dose. (author)

  5. Peripheral epithelial odontogenic tumor

    International Nuclear Information System (INIS)

    Carzoglio, J.; Tancredi, N.; Capurro, S.; Ravecca, T.; Scarrone, P.

    2006-01-01

    A new case of peripheral epithelial odontogenic tumor (Pindborg tumor) is reported. It is localized in the superior right gingival region, a less frequent site, and has the histopathological features previously reported. Immunochemical studies were performed, revealing a differential positive stain to cytokeratins in tumor cells deeply seated in the tumor mass, probably related to tumoral cell heterogeneity.Interestingly, in this particular case S-100 protein positive reactivity was also detected in arborescent cells intermingled with tumoral cells, resembling Langerhans cells. Even though referred in the literature in central Pindborg tumors, no references were found about their presence in peripheral tumors, like the one that is presented here

  6. Analyzing-power measurements of Coulomb-nuclear interference with the polarized-proton and -antiproton beams at 185 GeV/c

    Energy Technology Data Exchange (ETDEWEB)

    Akchurin, N; Onel, Y [Iowa Univ., Iowa City, IA (USA). Dept. of Physics; Carey, D; Coleman, R; Cossairt, J D; Read, A L [Fermi National Accelerator Lab., Batavia, IL (USA); Corcoran, M D; Nessi-Tedaldi, F; Nessi, M; Nguyen, C; Phillips, G C; Roberts, J B; White, J L [Rice Univ., Houston, TX (USA). Bonner Nuclear Labs.; Derevschikov, A; Matulenko, Yu A; Meschanin, A P; Nurushev, S B; Solovyanov, V L; Vasiliev, A N [Institut Fiziki Vysokikh Ehnergij, Serpukhov (USSR); Gazzaly, M M [Minnesota Univ., Minneapolis (USA). Dept. of Physics; Grosnick, D P; Hill, D; Laghai, M; Lopiano, D; Ohashi, Y; Shima, T; Spinka, H; Stanek, R W; Underwood, D G; Yokosawa, A [Argonne National Lab., IL (USA); Imai, K; Makino, S; Masaike, A; Miyake, K; Nagamine, T; Takeutchi, F; Tamura, N; Yoshida, T [Kyoto Univ. (Japan); Kuroda, K; Michalowicz, A [Institut National de Physique Nucleaire et de Physique des Particules, 74 - Annecy-le-Vieux (France). Lab. de P; E-581/704 Collaboration

    1989-10-12

    The analyzing power A{sub N} of proton-proton, proton-hydrocarbon, and antiproton-hydrocarbon scattering in the Coulomb-nuclear interference region has been measured using the 185 GeV/c Fermilab polarized-proton and -antiproton beams. The results are found to be consistent with theoretical predictions within statistical uncertainties. (orig.).

  7. Cosmic ray antiproton/electron discrimination capability of the CAPRICE silicon-tungsten calorimeter using neural networks

    International Nuclear Information System (INIS)

    Bellotti, R.; Boezio, M.; Castellano, M.; De Marzo, C.; Picozza, P.; Prigiobbe, V.; Sparvoli, R.; Tirocchi, M.

    1996-01-01

    A data analysis based on an artificial neural network classifier is proposed to identify cosmic ray antiprotons detected with the CAPRICE silicon-tungsten imaging calorimeter against electron background in the energy range 1.2-4.0 GeV. A set of new physical variables, describing the events inside the calorimeter on the base of their different patterns, are introduced in order to discriminate between hadronic and electromagnetic showers. The ability of the artificial neural network classifier to perform a careful multidimensional analysis gives the possibility to identify antiprotons with an electron rejection 408±85 (stat) at 95.0±0.2 (stat)% of signal detection efficiency. The high accuracy achieved by this method improves substantially the efficiency in the evaluation of the cosmic ray antiproton spectrum. (orig.)

  8. Advice concerning radiotherapy

    International Nuclear Information System (INIS)

    1984-01-01

    Dutch National cancer incidence figures were calculated by using the reliable data on cancer incidence in the Eindhoven area and population forecasts and information obtained from the Central Bureau of Statistics. Several radiotherapy departments suffer from under capacity (a lack of resources and understaffing). Data have also shown that 35% of cancer patients receive radiotherapy, instead of 50%. Calculations have been made by the committee on the present and future needs with regard to equipment and staff. In 1983, the number of megavoltage therapy units amounted to 38, but should have been 65. It should be 80 in 1990 and 90 in 2000. Since building and installing such equipment is a lengthy process a considerable effort is needed to make up for the arrears. The committee advocates the extension of the system of regional cooperation in cancer care (comprehensive cancer centres), in which radiotherapy departments play a crucial role. Working parties from the committee provided a comprehensive description of current radiotherapy practice with reference to physical, technical, clinical and management aspects. Another working party assessed the results of cancer treatment with regard to many different tumour sites. Recent and expected developments were analysed or indicated. The Radiotherapy Committee commissioned an external team to conduct a project to achieve a picture of future developments using methods different to those of the committee's. An interim advice has been added on this subject. (Auth.)

  9. High-precision comparison of the antiproton-to-proton charge-to-mass ratio.

    Science.gov (United States)

    Ulmer, S; Smorra, C; Mooser, A; Franke, K; Nagahama, H; Schneider, G; Higuchi, T; Van Gorp, S; Blaum, K; Matsuda, Y; Quint, W; Walz, J; Yamazaki, Y

    2015-08-13

    Invariance under the charge, parity, time-reversal (CPT) transformation is one of the fundamental symmetries of the standard model of particle physics. This CPT invariance implies that the fundamental properties of antiparticles and their matter-conjugates are identical, apart from signs. There is a deep link between CPT invariance and Lorentz symmetry--that is, the laws of nature seem to be invariant under the symmetry transformation of spacetime--although it is model dependent. A number of high-precision CPT and Lorentz invariance tests--using a co-magnetometer, a torsion pendulum and a maser, among others--have been performed, but only a few direct high-precision CPT tests that compare the fundamental properties of matter and antimatter are available. Here we report high-precision cyclotron frequency comparisons of a single antiproton and a negatively charged hydrogen ion (H(-)) carried out in a Penning trap system. From 13,000 frequency measurements we compare the charge-to-mass ratio for the antiproton (q/m)p- to that for the proton (q/m)p and obtain (q/m)p-/(q/m)p − 1 =1(69) × 10(-12). The measurements were performed at cyclotron frequencies of 29.6 megahertz, so our result shows that the CPT theorem holds at the atto-electronvolt scale. Our precision of 69 parts per trillion exceeds the energy resolution of previous antiproton-to-proton mass comparisons as well as the respective figure of merit of the standard model extension by a factor of four. In addition, we give a limit on sidereal variations in the measured ratio of baryonic antimatter, and it sets a new limit on the gravitational anomaly parameter of |α − 1| < 8.7 × 10(-7).

  10. Exploration of a High Luminosity 100 TeV Proton Antiproton Collider

    Energy Technology Data Exchange (ETDEWEB)

    Oliveros, Sandra J. [Univ. of Mississippi, Oxford, MS (United States); Summers, Don [Univ. of Mississippi, Oxford, MS (United States); Cremaldi, Lucien [Univ. of Mississippi, Oxford, MS (United States); Acosta, John [Univ. of Mississippi, Oxford, MS (United States); Neuffer, David [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

    2017-04-12

    New physics is being explored with the Large Hadron Collider at CERN and with Intensity Frontier programs at Fermilab and KEK. The energy scale for new physics is known to be in the multi-TeV range, signaling the need for a future collider which well surpasses this energy scale. We explore a 10$^{\\,34}$ cm$^{-2}$ s$^{-1}$ luminosity, 100 TeV $p\\bar{p}$ collider with 7$\\times$ the energy of the LHC but only 2$\\times$ as much NbTi superconductor, motivating the choice of 4.5 T single bore dipoles. The cross section for many high mass states is 10 times higher in $p\\bar{p}$ than $pp$ collisions. Antiquarks for production can come directly from an antiproton rather than indirectly from gluon splitting. The higher cross sections reduce the synchrotron radiation in superconducting magnets and the number of events per beam crossing, because lower beam currents can produce the same rare event rates. Events are more centrally produced, allowing a more compact detector with less space between quadrupole triplets and a smaller $\\beta^{*}$ for higher luminosity. A Fermilab-like $\\bar p$ source would disperse the beam into 12 momentum channels to capture more antiprotons. Because stochastic cooling time scales as the number of particles, 12 cooling ring sets would be used. Each set would include phase rotation to lower momentum spreads, equalize all momentum channels, and stochastically cool. One electron cooling ring would follow the stochastic cooling rings. Finally antiprotons would be recycled during runs without leaving the collider ring by joining them to new bunches with synchrotron damping.

  11. The BESS Search for Cosmic-Ray Antiproton Origins and for Cosmological Antimatter

    Science.gov (United States)

    Mitchell, John; Yamamoto, Akira

    2009-01-01

    The apex of the Balloon-borne Experiment with a Superconducting Spectrometer (BESS) program was reached with the Antarctic flight of BESS-Polar II, during the 2007-2008 Austral Summer, that obtained 24.5 days of data on over 4.7 billion cosmic-ray events. The US-Japan BESS Collaboration uses elementary particle measurements to study the early Universe and provides fundamental data on the spectra of light cosmic-ray elements and isotopes. BESS measures the energy spectra of cosmic-ray antiprotons to investigate signatures of possible exotic sources, such as dark-matter candidates, and searches for heavier antinuclei that might reach Earth from antimatter domains formed during symmetry breaking processes in the early Universe. Since 1993, BESS has carried out eleven high-latitude balloon flights, two of long duration, that together have defined the study of antiprotons below about 4 GeV, provided standard references for light element and isotope spectra, and set the most sensitive limits on the existence of antideuterons and antihelium. The BESS-Polar II flight took place at Solar Minimum, when the sensitivity of the low-energy antiproton measurements to a primary source is greatest. The rich BESS-Polar II dataset more than doubles the combined data from all earlier BESS flights and has 10-20 times the statistics of BESS data from the previous Solar Minimum. Here, we summarize the scientific results of BESS program, focusing on the results obtained using data from the long-duration flights of BESS-Polar I (2004) and BESS-Polar II.

  12. Revisit of cosmic ray antiprotons from dark matter annihilation with updated constraints on the background model from AMS-02 and collider data

    Science.gov (United States)

    Cui, Ming-Yang; Pan, Xu; Yuan, Qiang; Fan, Yi-Zhong; Zong, Hong-Shi

    2018-06-01

    We study the cosmic ray antiprotons with updated constraints on the propagation, proton injection, and solar modulation parameters based on the newest AMS-02 data near the Earth and Voyager data in the local interstellar space, and on the cross section of antiproton production due to proton-proton collisions based on new collider data. We use a Bayesian approach to properly consider the uncertainties of the model predictions of both the background and the dark matter (DM) annihilation components of antiprotons. We find that including an extra component of antiprotons from the annihilation of DM particles into a pair of quarks can improve the fit to the AMS-02 antiproton data considerably. The favored mass of DM particles is about 60~100 GeV, and the annihilation cross section is just at the level of the thermal production of DM (langleσvrangle ~ O(10‑26) cm3 s‑1).

  13. Peripheral Artery Disease

    Science.gov (United States)

    ... pressure High blood cholesterol Coronary heart disease Stroke Metabolic syndrome Screening and Prevention Taking action to control your risk factors can help prevent or delay peripheral artery disease (P.A.D.) and its complications. Know your family history of health problems related to P.A. ...

  14. Promoting peripheral myelin repair.

    Science.gov (United States)

    Zhou, Ye; Notterpek, Lucia

    2016-09-01

    Compared to the central nervous system (CNS), peripheral nerves have a remarkable ability to regenerate and remyelinate. This regenerative capacity to a large extent is dependent on and supported by Schwann cells, the myelin-forming glial cells of the peripheral nervous system (PNS). In a variety of paradigms, Schwann cells are critical in the removal of the degenerated tissue, which is followed by remyelination of newly-regenerated axons. This unique plasticity of Schwann cells has been the target of myelin repair strategies in acute injuries and chronic diseases, such as hereditary demyelinating neuropathies. In one approach, the endogenous regenerative capacity of Schwann cells is enhanced through interventions such as exercise, electrical stimulation or pharmacological means. Alternatively, Schwann cells derived from healthy nerves, or engineered from different tissue sources have been transplanted into the PNS to support remyelination. These transplant approaches can then be further enhanced by exercise and/or electrical stimulation, as well as by the inclusion of biomaterial engineered to support glial cell viability and neurite extension. Advances in our basic understanding of peripheral nerve biology, as well as biomaterial engineering, will further improve the functional repair of myelinated peripheral nerves. Copyright © 2016 Elsevier Inc. All rights reserved.

  15. A search for resonances in the antiproton-proton system at low energies

    International Nuclear Information System (INIS)

    Walczak, R.

    1981-01-01

    The excitation function of the annihilation and elastic cross-sections for the antiproton-proton scattering have been measured in the mass range from 1910 to 1978 MeV. The experiment was characterized by a mass resolution of about 0.4 MeV (R.M.S.) and a statistical significance of 1.2% (R.M.S.) for the annihilation channel. With this precision a narrow structure at a mass of 1936 MeV was observed. This structure is not of a simple Breit-Wigner shape. However, it might be identified with the S-meson reported by a previous experiment. (orig.)

  16. Highlights on gamma rays, neutrinos and antiprotons from TeV Dark Matter

    Directory of Open Access Journals (Sweden)

    Gammaldi Viviana

    2016-01-01

    Full Text Available It has been shown that the gamma-ray flux observed by HESS from the J1745-290 Galactic Center source is well fitted as the secondary gamma-rays photons generated from Dark Matter annihilating into Standard Model particles in combination with a simple power law background. The neutrino flux expected from such Dark Matter source has been also analyzed. The main results of such analyses for 50 TeV Dark Matter annihilating into W+W− gauge boson and preliminary results for antiprotons are presented.

  17. Basic physics program for a low energy antiproton source in North America

    International Nuclear Information System (INIS)

    Bonner, B.E.; Nieto, M.M.

    1987-01-01

    We summarize much of the important science that could be learned at a North American low energy antiproton source. It is striking that there is such a diverse and multidisciplinary program that would be amenable to exploration. Spanning the range from high energy particle physics to nuclear physics, atomic physics, and condensed matter physics, the program promises to offer many new insights into these disparate branches of science. It is abundantly clear that the scientific case for rapidly proceeding towards such a capability in North America is both alluring and strong. 38 refs., 2 tabs

  18. Status of the anti-proton production beam in the CERN PS

    International Nuclear Information System (INIS)

    Cappi, R.; Evans, B.J.; Garoby, R.

    1990-01-01

    A new scheme was put into operation in November 1988 to upgrade the proton beam delivered by the 26 GeV Proton Synchrotron (PS) for anti-proton production. It makes use of quasi-adiabatic manipulations of the RF parameters to squeeze a beam filling 1/2 of the PS circumference into a 1/4 turn and can in theory preserve the longitudinal emittance. A maximum intensity of 1.68 e 13 ppp in 5 bunches at 26 GeV has been reached in the course of 22 weeks of operation. The limitations of the performance are analysed together with possible improvements. (author) 6 refs., 9 figs

  19. The FLUKA study of the secondary particles fluence in the AD-Antiproton Decelerator target area

    CERN Document Server

    Calviani, M

    2014-01-01

    In this paper we present Monte Carlo FLUKA simulations [1, 2] carried out to investigate the secondary particles fluence emerging from the antiproton production target and their spatial distribution in the AD target area. The detailed quantitative analysis has been performed for different positions along the magnet dog-leg as well as after the main collimator. These results allow tuning the position of the new beam current transformers (BCT) in the target area, in order to have a precise pulse-by-pulse evaluation of the intensity of negative particles injected in the AD-ring before the deceleration phase.

  20. Atomic physics at the future facility for antiproton and ion research: status report 2014

    International Nuclear Information System (INIS)

    Gumberidze, A; Stöhlker, Th; Litvinov, Yu A

    2015-01-01

    In this contribution, a brief overview of the Stored Particle Atomic physics Research Collaboration scientific program at the upcoming Facility for Antiproton and Ion Research (FAIR) is given. The program comprises a very broad range of research topics addressing atomic structure and dynamics in hitherto unexplored regimes, light–matter interactions, lepton pair production phenomena, precision tests of quantum electrodynamics and standard model in the regime of extreme fields and many more. We also present the current strategy for the realization of the envisioned physics program within the modularized start version (MSV) of FAIR. (paper)

  1. Kickers and power supplies for the Fermilab Tevatron I antiproton source

    International Nuclear Information System (INIS)

    Castellano, T.; Bartoszek, L.; Tilles, E.; Petter, J.; McCarthy, J.

    1985-05-01

    The Fermilab Antiproton Source Accumulator and Debuncher rings require 5 kickers in total. These range in design from conventional ferrite delay line type magnets, with ceramic beam tubes to mechanically complex shuttered kickers situated entirely in the Accumulator Ring's 10 -10 torr vacuum. Power supplies are thyratron switched pulse forming networks that produce microsecond width pulses of several kiloamps with less than 30 nanoseconds rise and fall times. Kicker and power supply design requirements for field strength, vacuum, rise and fall time, timing and magnetic shielding of the stacked beam in the accumulator by the eddy current shutter will be discussed. 8 refs., 3 figs., 2 tabs

  2. Antiproton-proton annihilations into four prongs at 7.2 GeV/c

    International Nuclear Information System (INIS)

    Leeuw, A. de.

    1979-01-01

    Annihilation reactions are described in which four charged pions and also maybe uncharged particles are produced. Data was acquired in an antiproton-proton experiment at a beam momentum of 7.2 GeV/c and 220K pictures of the CERN 2m HBC were measured. Cross sections have been determined and angular distributions of the pions and of some resonances are given. Two models that describe annihilation reactions are treated, the so called CLA model and a simple quark model. (C.F./Auth.)

  3. Measurement of (anti)deuteron and (anti)proton production in DIS at HERA

    International Nuclear Information System (INIS)

    Chekanov, S.; Derrick, M.; Magill, S.

    2007-05-01

    The first observation of (anti)deuterons in deep inelastic scattering at HERA has been made with the ZEUS detector at a centre-of-mass energy of 300-318 GeV using an integrated luminosity of 120 pb -1 . The measurement was performed in the central rapidity region for transverse momentum per unit of mass in the range 0.3 T /M<0.7. The particle rates have been extracted and interpreted in terms of the coalescence model. The (anti)deuteron production yield is smaller than the (anti)proton yield by approximately three orders of magnitude, consistent with the world measurements. (orig.)

  4. Rapidity distributions of antiprotons in Si+A and Au+A collisions

    Energy Technology Data Exchange (ETDEWEB)

    Shiva Kumar, B [Yale Univ., New Haven, CT (United States); Beavis, D; Bennett, M; Carroll, J B; Chiba, J; Crawford, H J; Debbe, R; Doke, T; Engelage, J; Greiner, L; Hayano, R S; Hallman, T J; Heckman, H H; Kashiwagi, T; Kikuchi, J; Kuo, C; Lindstrom, P J; Mitchell, J W; Nagamiya, S; Pope, K; Stankus, P; Tanaka, K H; Welsh, R C; Zhan, W; E858/E878 Collaboration

    1994-01-03

    We have studied the production of {pi}{sup {+-}}, K{sup {+-}}, p, anti p, and light nuclei in relativistic Si+nucleus and Au+nucleus collisions using a zero degree focusing spectrometer. We find that for the antiprotons, the width of the rapidity distribution measured at p{sub t}=0 increases in going from Si+Al collisions to Au+Au collisions in spite of the lower center of mass energy of the latter measurement. We discuss our data, and the implications of our measurement. We also report sensitivity limits on the production of exotic particles. (orig.)

  5. Performance of the CERN plasma lens in laboratory and beam tests at the Antiproton Source

    International Nuclear Information System (INIS)

    Kowalewicz, R.; Lubrano di Scampamorte, M.; Milner, S.; Pedersen, F.; Riege, H.; Christiansen, J.; Frank, K.; Stetter, M.; Tkotz, R.; Boggasch, E.

    1991-01-01

    The CERN plasma lens is based on a dynamic z-pinch which creates during 500 ns a cylindrical plasma current conductor of 290 mm length and 38 to 45 mm diameter. The lens is designed for pulsed pinched currents of 400 kA and magnetic field gradients of 200 T/m produced with stored energies of 56 kJ. Life tests of different lens components were carried through at a repetition rate of 4.8 s/pulse. The results of the first beam tests of the plasma lens at the CERN antiproton source are very encouraging in view of other potential plasma lens applications

  6. Measurement of the Transverse Momentum of Dielectron Pairs in Proton - Anti-Proton Collisions

    Energy Technology Data Exchange (ETDEWEB)

    Casey, Dylan Patrick [Univ. of Rochester, NY (United States)

    1997-01-01

    We present a measurement of the transverse momentum distribution of dielectron pairs with invariant mass near the mass of the Z boson. The data were obtained using the DO detector during the 1994-1995 run of the Tevatron Co!lider at Fermilab. The data used in the measurement corresponds to an integrated luminosity of 108.5 $pb^{-1}$ The measurement is compared to current phenomenology for vector boson production in proton-antiproton interactions, and the results are found to be consistent with expectation from Quantum Chromodynamics (QCD).

  7. A new description of high energy antiproton (proton)-proton elastic scattering

    International Nuclear Information System (INIS)

    Barshay, S.; Technion-Israel Inst. of Tech., Haifa. Dept. of Physics); Goldberg, J.

    1987-01-01

    We develop a generalization of the geometric picture for high-energy antiproton (proton)-proton elastic scattering. The eikonal at each impact parameter is considered to have fluctuations about an average value, and is thus characterized by a distribution. A connection to parton branching is made through the specific form of the distribution function for the eikonal. A unified physical theory with significant fluctuations accurately describes the anti p(p)-p data at both √s = 546 GeV and 53 GeV. The fluctuation parameter is remarkably well given by that directly observed in multiparticle production. (orig.)

  8. New description of high energy antiproton (proton)-proton elastic scattering

    Energy Technology Data Exchange (ETDEWEB)

    Barshay, S; Goldberg, J

    1987-10-15

    We develop a generalization of the geometric picture for high-energy antiproton (proton)-proton elastic scattering. The eikonal at each impact parameter is considered to have fluctuations about an average value, and is thus characterized by a distribution. A connection to parton branching is made through the specific form of the distribution function for the eikonal. A unified physical theory with significant fluctuations accurately describes the anti p(p)-p data at both ..sqrt..s = 546 GeV and 53 GeV. The fluctuation parameter is remarkably well given by that directly observed in multiparticle production.

  9. Colliding beam physics at Fermilab: interaction regions, beam storage, antiproton cooling, production, and colliding

    Energy Technology Data Exchange (ETDEWEB)

    Walker, J.K. (ed.)

    1977-01-01

    The purpose of the colliding beams experment department at Fermilab was to bring about collisions of the stored beams in the energy doubler/saver and main ring, and construct experimental areas with appropriate detectors. To explore the feasibility of using the main ring as a storage device, several studies were carried out to investigate beam growth, loss, and the backgrounds in detectors at possible intersection regions. This range of developments constituted the major topics at the 1977 Summer Study reported here. Emphasis in part one is on interaction regions, beam storage, antiproton cooling, production, and colliding. 40 papers from this part are included in the data base. (GHT)

  10. Chemotherapy disruption of efficient radiotherapy

    International Nuclear Information System (INIS)

    Nervi, C.; Friedman, M.

    1974-01-01

    Studies on the use of chemotherapy in combination with radiotherapy are reviewed. Some topics discussed are: indications for the use of combined chemotherapy and radiotherapy; improvement of the therapeutic ratio following the use of methotrexate; advantages of preirradiation and postirradiation chemotherapy; side effects following simultaneous chemotherapy and radiotherapy; and effects of chemotherapy on cure rate of radiosensitive and radioresistant tumors. (U.S.)

  11. Radiotherapy of pineal tumors

    International Nuclear Information System (INIS)

    Danoff, B.; Sheline, G.E.

    1984-01-01

    Radiotherapy has universally been used in the treatment of pineal tumors and suprasellar germinomas. Recently however, major technical advances related to the use of the operating microscope and development of microsurgical techniques have prompted a renewed interest in the direct surgical approach for biopsy and/or excision. This interest has resulted in a controversy regarding the role of surgery prior to radiotherapy. Because of the heterogeneity of tumors occurring in the pineal region (i.e., germ cell tumors, pineal parenchymal tumors, glial tumors, and cysts) and their differing biological behavior, controversy also surrounds aspects of radiotherapy such as: the optimal radiation dose, the volume to be irradiated, and indications for prophylactic spinal irradiation. A review of the available data is presented in an attempt to answer these questions

  12. Cancer research and radiotherapy

    International Nuclear Information System (INIS)

    Matsuzawa, Taiju

    1978-01-01

    An actual condition of cancer, and the basis and a future view of radiotherapy were described by adding generally established biological and biochemical knowledge to the author's research. It was described that the relapse of cancer after irradiation was induced from outside of cancerous mass, and the nature of relapsed cancerous cells group was also stated. The histological structure of cancer from a view of cell movement and radioresistant cancerous cells group were described. The differentiation of cancerous cells were described, and a study of inhibition of cancer by redifferentiation was considered. It is important to grasp characteristics and a limit of radiotherapy for cancer, to systematize and materialize reasonable therapy which uses drug and immunotherapy together with surgery, and to use radiotherapy reasonably together with redifferentiation therapy of cancerous cells by extracting characteristics and a limit of radiationtherapy from an actual condition of cancer. (Serizawa, K.)

  13. Measurement of antiproton production in $p$He collisions at $\\sqrt{s_{\\scriptscriptstyle\\rm NN}}=110$ GeV

    CERN Document Server

    The LHCb Collaboration

    2017-01-01

    The antiproton production cross-section in collisions of a 6.5 TeV LHC proton beam on helium at rest is measured by the LHCb experiment using the SMOG internal gas target from a dataset corresponding to an integrated luminosity of 0.4 $\\text{nb}^{-1}$. This is the first direct measurement of antimatter production in $p$He collisions, and has important implications for the interpretation of recent results from the PAMELA and AMS-02 experiments, which measure the antiproton component in cosmic rays outside of the Earth's atmosphere.

  14. Study on the properties of leading protons and antiprotons from exclusive anti pp reactions at 32 GeV/c

    International Nuclear Information System (INIS)

    Bogolyubskij, M.Yu.; Borovikov, A.A.; Boos, Eh.G.

    1986-01-01

    The leading properties of protons and antiprotons from the nondiffractive events are studied for p-barp-exclusive reactions at 32 GeV/c. It is found that the relative leading effect of protons and antiprotons does not depend on the final-state multiplicity and that the longitudinal moments of the leading hadrons are uncorrelated, but a significant part of the transverse momentum of a leading hadron is compensated by the transverse momentum of another leading hadron. It is shown that these experimental facts are described well by a statistical jet-independent model but contradict the Lund string-fragmentation model

  15. Proceedings of the Antiproton Science and Technology Workshop Held in Santa Monica, California on 6-9 October 1987

    Science.gov (United States)

    1988-07-01

    34 pp. 221-232, Positron Studies of Solids, Surfaces, and Atoms, Allen P. Mills, Jr., William S. Crane, and Karl F. Canter, Eds., Proceedings Symposium...quoted for antimatter in the Walgate article of 133 MS/mg was based on the wrong /p ratio; it should be 15 M$/mg.] B. Schwarzschild , "Laser Beam Focus...particles.") B. Schwarzschild , "Now They’re Even Trapping Antiprotons," Physics Today 39, No. 9, 19 (Sept 1986). Arthur L. Robinson, "Antiprotons Captured

  16. Calculations of antiproton nucleus quasi-bound states using the Paris (N)over-barN potential

    Czech Academy of Sciences Publication Activity Database

    Hrtánková, Jaroslava; Mareš, Jiří

    2018-01-01

    Roč. 969, č. 1 (2018), s. 45-59 ISSN 0375-9474 R&D Projects: GA ČR(CZ) GA15-04301S Institutional support: RVO:61389005 Keywords : antiproton-nucleus interaction * Paris (N)over-barN potential * antiproton-nuclear bound states Subject RIV: BE - Theoretical Physics OBOR OECD: Atomic, molecular and chemical physics ( physics of atoms and molecules including collision, interaction with radiation, magnetic resonances, Mössbauer effect) Impact factor: 1.916, year: 2016

  17. Radiotherapy for the medulloblastoma

    International Nuclear Information System (INIS)

    Gose, Kyuhei; Imajo, Yoshinari; Imanaka, Kazufumi

    1983-01-01

    Eighteen patients with medulloblastoma, treated between 1972 and 1981, at Kobe University School of Medicine, were retrospectively studied. Of those completing post operative irradiation, 50% have survived for 2 years, 15% for 5 years and mean survival periods was 22.2 months. 13 out of 18 patients developed local recurrence and spinal dissemination. The mean time from the initial radiotherapy to recurrence was 8.5 months. It was suggested that posterior fossa should recieve 5,000 rad, the spine should 2,000 rad and recurrences should be treated by the combination of radiotherapy and chemotherapy. (author)

  18. Arterial disease after radiotherapy

    International Nuclear Information System (INIS)

    Bigot, J.M.; Mathieu, D.; Reizine, D.

    1983-01-01

    Disease of the large arterial vessels is a relatively unknown complication of radiotherapy. However, it should be considered in the same manner as the other complications of irradiation when a tumour recurrence is suspected. The experimental studies of Kirkpatrick and Konings, demonstrating the synergy between irradiation and hypercholesterolemia in the precocity and gravity of vascular complications are recalled. The different localisations reported in the litterature are discussed: coronary, pulmonary, thoracic aorta, supra aortic, renal, digestive and ilio-femoral arteries. Finally, the difficulty of diagnosis of post-radiotherapy without clinical, radiological or anatomopathological confirmation, is underlined [fr

  19. Second cancers following radiotherapy

    International Nuclear Information System (INIS)

    Tubiana, M.

    1983-01-01

    Published reports have shown that there is an increased incidence of second malignancies, particularly sarcomas, following high dose radiotherapy in cancer treatment. However, this increased risk is very small and is relatively negligeable when one considers the beneficial effects of radiotherapy in cancer treatment. This incidence of radiation induced cancer appears to be higher in certain groups of patients, such as children and patients with Hodgkin's disease. In view of scarcity of published data, controlled surveys remain necessary for the quantitative assessment of the cancer risk in various subgroups of irradited patients [fr

  20. Xerostomia induced by radiotherapy

    Directory of Open Access Journals (Sweden)

    Alimi D

    2015-08-01

    Full Text Available David Alimi Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh, PA, USAWe read with great interest the excellent review on xerostomia induced by radiotherapy, by Pinna et al.1 The authors should be congratulated for a very detailed review of the physiopathology, clinical symptoms, and therapeutic management of an extremely difficult condition. Although we agree that the use of anticholinergic medication represents treatment, it requires the patient to have residual salivary gland function. Unfortunately, it is well established that in most cases radiotherapy destroys most of the salivary gland and associated salivary secretions.