WorldWideScience

Sample records for annual midyear topical

  1. Status Report on Nationally Appropriate Mitigation Actions (NAMAs). Mid-year update June 2013

    Energy Technology Data Exchange (ETDEWEB)

    Van Tilburg, X.; Bristow, S. [ECN Policy Studies, Amsterdam (Netherlands); Roeser, F.; Escalante, D.; Fekete, H. [Ecofys, Cologne (Germany)

    2013-06-15

    This mid-year update of the Annual Status Report on Nationally Appropriate Mitigation Actions, last published by Ecofys and ECN in November 2012, highlights recent trends in NAMA development and support and identifies where more progress is needed.

  2. TFA Tanks Focus Area midyear review report FY 2000

    Energy Technology Data Exchange (ETDEWEB)

    LR Roeder-Smith

    2000-05-02

    In accordance with EM's office of Science and Technology (OST), the TFA is committed to assessing the maturity of technology development projects and ensuring their readiness for implementation and subsequent deployment. The TFA conducts an annual Midyear Review to document the status of ongoing projects, reaffirm and document user commitment to selected projects, and to improve the effective deployment of technology by determining and documenting the readiness of selected projects to move ahead. Since 1995, OST has used a linear technology maturation model that spans through seven defined stages of maturity, from basic research to implementation. Application of this Stage/Gate model to technology development resulted in prescriptive and somewhat cumbersome review procedures, resulting in limited and inconsistent use. Subsequently, in February 2000, OST issued revised guidance in an effort to streamline the technology tracking and review process. While the new OST guidance reinforces peer review requirements and the use of the American Society of Mechanical Engineers (ASME) for independent reviews, it also implements a simplified Gate model. The TFA is now responsible for providing auditable documentation for passing only three stages of technology maturity: ready for research (Gate 0); ready for development (Gate 2); ready for demonstration (Gate 5). The TFA Midyear Review is a key element in the overall review procedure, as the tracking evidence for all active projects is required to be available at this time. While the Midyear Report contains an overview of the status of all TFA reviews and projects, not all the reviews were conducted during the Midyear Review. The TFA used a phased approach to accomplish the Midyear Review requirements.

  3. An annual topic highlight: Alcohol and liver, 2011

    Institute of Scientific and Technical Information of China (English)

    Natalia A Osna

    2011-01-01

    An annual topic highlight: Alcohol and Liver, 2011, covers the important and new aspects of pathogenesis of alcoholic liver diseases (ALD). It includes broad topics ranging from the exacerbation of ALD by infectious (viral) agents (hepatitis C virus and human immunodeficiency virus) to the influence of alcohol on liver fibrogenesis, lipid rafts, autophagy and other aspects. This issue is recommended for both basic scientists and clinicians who are involved in alcoholic liver research.

  4. 2011 annual meeting on nuclear technology. Topical sessions. Pt. 5; Jahrestagung Kerntechnik 2011. Fachsitzungsberichte. T. 5

    Energy Technology Data Exchange (ETDEWEB)

    Fazio, Concetta [Karlsruhe Institute of Technology (KIT), Eggenstein-Leopoldshafen (Germany). Nuclear Safety Research Programme

    2011-12-15

    Summary report on the Topical Session of the Annual Conference on Nuclear Technology held in Berlin, 17 to 19 May 2011: - Sodium Cooled Fast Reactors. The reports on the Topical Sessions: - CFD-Simulations for Safety Relevant Tasks, - Final Disposal: From Scientific Basis to Application, - Characteristics of a High Reliability Organization (HRO) Considering Experience Gained from Events at Nuclear Power Stations, and - Nuclear Competence in Germany and Europe have been covered in atw 7, 8/9, 10 and 11 (2011). (orig.)

  5. 2009 Annual meeting on nuclear technology. Pt. 2. Topical sessions; Jahrestagung Kerntechnik 2009. T.2. Fachsitzungsberichte

    Energy Technology Data Exchange (ETDEWEB)

    Fazio, Concetta [Forschungszentrum Karlsruhe/KIT, Eggenstein-Leopoldshafen (Germany); Delpech, Marc [Centre CEA de Saclay (Essonne), Gif-sur-Yvette (France); Schaffrath, Andreas [TUeV NORD SysTec GmbH und Co. KG, Abt. Sicherheitsanalyse und Systemtechnik (ETB), Hamburg (Germany)

    2009-10-15

    Summary report on the Topical Sessions of the Annual Conference on Nuclear Technology held in Dresden, May 12 to 14, 2009: Flexible Concept for Sustainable Use of Nuclear Energy and Waste Minimization; Thermohydraulic Experiments for Reactors of the Second and Third Generation. The reports on the Topical Sessions: Advances in the Development of Integrated Management Systems for the Optimisation of Safety and Operational Availability of Nuclear Power Stations (Dr. Markus Nie and Dipl.-Ing. Karl Ramler), and; Fuel Elements: Zero Failure - Road to the Target (Dipl.-Ing. Andreas Huettmann) have been covered in atw 8/9 (2009). (orig.)

  6. 47{sup th} Annual meeting on nuclear technology (AMNT 2016). Key Topics / Enhanced safety and operation excellence

    Energy Technology Data Exchange (ETDEWEB)

    Bohnstedt, Angelika [Karlsruher Institut fuer Technologie (KIT), Eggenstein-Leopoldshafen (Germany). Programm Nukleare Entsorgung, Sicherheit und Strahlenforschung (NUSAFE); Baumann, Erik [AREVA GmbH, Erlangen (Germany). Radiation Protection

    2016-12-15

    Summary report on the Key Topic 'Enhanced Safety and Operation Excellence' Focus Session 'Radiation Protection' of the 47{sup th} Annual Meeting on Nuclear Technology (AMNT 2016) held in Hamburg, 10 to 12 May 2016. Other Sessions of AMNT 2016 have been and will be covered in further issues of atw.

  7. 47{sup th} Annual meeting on nuclear technology (AMNT 2016). Key topic / Outstanding know-how and sustainable innovations

    Energy Technology Data Exchange (ETDEWEB)

    Zwermann, Winfried [Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS) gGmbH, Garching (Germany). Forschungszentrum

    2016-11-15

    Summary report on the Key Topic ''Outstanding Know-How and Sustainable Innovations'' Technical Session ''Reactor Physics, Thermo, and Fluid Dynamics'' of the 47th Annual Conference on Nuclear Technology (AMNT 2016) held in Hamburg, 10 to 12 May 2016. Other Sessions of AMNT 2016 have been and will be covered in further issues of atw.

  8. NASA Physical Sciences - Presentation to Annual Two Phase Heat Transfer International Topical Team Meeting

    Science.gov (United States)

    Chiaramonte, Francis; Motil, Brian; McQuillen, John

    2014-01-01

    The Two-phase Heat Transfer International Topical Team consists of researchers and members from various space agencies including ESA, JAXA, CSA, and RSA. This presentation included descriptions various fluid experiments either being conducted by or planned by NASA for the International Space Station in the areas of two-phase flow, flow boiling, capillary flow, and crygenic fluid storage.

  9. 47{sup th} Annual conference on nuclear technology (AMNT 2016). Key topics / Outstanding know-how and sustainable innovations - enhanced safety and operation excellence

    Energy Technology Data Exchange (ETDEWEB)

    Raetzke, Christian [CONLAR - Consulting on Nuclear Law, Licensing and Regulation, Leipzig (Germany); Fischer, Erwin [PreussenElektra GmbH, Hannover (Germany). Management Board; Mohrbach, Ludger [VGB PowerTech e.V., Essen (Germany). Competence Center ' ' Nuclear Power Plants' '

    2016-08-15

    Summary report on the Key Topics ''Outstanding Know-How and Sustainable Innovations'' and ''Enhanced Safety and Operation Excellence'' of the 47{sup th} Annual Conference on Nuclear Technology (AMNT 2016) held in Hamburg, 10 to 12 May 2016. Other Sessions of AMNT 2016 will be covered in further issues of atw.

  10. The Relationship between Mid-Year Benchmark and End-of-Grade Assessments: 2010-11. D&A Report No. 11.24

    Science.gov (United States)

    McMillen, Brad

    2012-01-01

    This analysis was conducted to examine the relationship between Wake Count Public Schools' students' performance on mid-year benchmark assessments and End-of-Grade (EOG) tests in both reading and math in grades 3-5 in school year 2010-11. Strong positive correlations were found between the mid-year benchmark assessment and EOG test scores for each…

  11. 46{sup th} Annual meeting on nuclear technology (AMNT 2015). Key topic / Enhanced safety and operation excellence / Sustainable reactor operation management - safe, efficient, valuable

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, Erwin [E.ON Kernkraft GmbH, Global Unit Next Generation, Hannover (Germany)

    2015-08-15

    Summary report on the following Topical Session of the 46{sup th} Annual Conference on Nuclear Technology (AMNT 2015) held in Berlin, 5 to 7 May 2015: - Sustainable Reactor Operation Management - Safe, Efficient, Valuable (Erwin Fischer) The other Sessions of the Key Topics - ''Outstanding Know-How and Sustainable Innovations'', - ''Enhanced Safety and Operation Excellence'' and - ''Decommissioning Experience and Waste Management Solutions'' have been covered in atw 7 (2015) and will be covered in further issues of atw.

  12. 47{sup th} Annual meeting on nuclear technology (AMNT 2016). Key Topics / Enhanced safety and operation excellence and decommissioning experience and Waste management solutions

    Energy Technology Data Exchange (ETDEWEB)

    Salnikova, Tatiana [AREVA GmbH, Erlangen (Germany); Schaffrath, Andreas [Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS) gGmbH, Garching (Germany)

    2016-10-15

    Summary report on the Key Topics ''Enhanced Safety and Operation Excellence'' and ''Decommissioning Experience and Waste Management Solutions'' of the 47{sup th} Annual Conference on Nuclear Technology (AMNT 2016) held in Hamburg, 10 to 12 May 2016. Other Sessions of AMNT 2016 have been and will be covered in further issues of atw.

  13. Topical report review status

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-08-01

    This report provides industry with procedures for submitting topical reports, guidance on how the U.S. Nuclear Regulatory Commission (NRC) processes and responds to topical report submittals, and an accounting, with review schedules, of all topical reports currently accepted for review schedules, of all topical reports currently accepted for review by the NRC. This report will be published annually. Each sponsoring organization with one or more topical reports accepted for review copies.

  14. 47{sup th} Annual meeting on nuclear technology (AMNT 2016). Key topic / Outstanding know-how and sustainable innovations

    Energy Technology Data Exchange (ETDEWEB)

    Schaffrath, Andreas [Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS) gGmbH, Garching (Germany). Bereich Reaktorsicherheitsforschung

    2016-07-15

    Summary report on the Technical Session: ''Reactor Physics, Thermo- and Fluid-Dynamics'' of the 47th Annual Conference on Nuclear Technology (AMNT 2016) held in Hamburg, 10 to 12 May 2016. Other Sessions of AMNT 2016 will be covered in further issues of atw.

  15. Bimatoprost Topical

    Science.gov (United States)

    Topical bimatoprost is used to treat hypotrichosis (less than the normal amount of hair) of the eyelashes by promoting ... growth of longer, thicker, and darker lashes. Topical bimatoprost is in a class of medications called prostaglandin ...

  16. The hot topics of acute leukemia: reports in the 56th ASH annual meeting%急性白血病研究热点:第56届美国血液学会年会报道

    Institute of Scientific and Technical Information of China (English)

    魏辉

    2014-01-01

    第56届美国血液学会年会(ASH)在急性白血病领域主要对以下6个问题给予了关注:一系列临床研究对白血病前体细胞进行了探索性研究;急性髓系白血病(AML)化疗研究主要集中于大剂量柔红霉素的应用;AML的靶向治疗主要是酪氨酸激酶抑制剂(TKI)的应用;急性早幼粒细胞白血病(APL)治疗研究集中于砷剂的应用;异柠檬酸脱氢酶2(IDH2)抑制剂AG221和MDM2抑制剂RG7388是目前非常有上市前景的靶向治疗新药;嵌合抗原受体修饰的T细胞(CAR-T细胞)的免疫治疗是急性淋巴细胞白血病(ALL)领域的热点.%There are six main topics in acute leukemia at 56th (2014) American Society of Hematology annual meeting.The preleukemic cells were investigated in serial clinical trials.The application of High dose daunorbicin is the main topic in the area of acute myeloid leukemia (AML) chemotherapy.The application of tyrosine kinase inhibitors is the main topic in the area of target therapy of AML.The application of arsenic is the main topic in the area of acute promyelocytic leukemia (APL) treatment.AG221,an IDH2 inhibitor,and RG7388,MDM2 inhibitor,are promising target drugs for AML.CAR-T cellular immunotherapy is the hot topic in acute lymphoblastic leukemia (ALL).

  17. 46{sup th} annual meeting on nuclear technology (AMNT 2015). Key topics / Outstanding know-how and sustainable innovations enhanced safety and operation excellence

    Energy Technology Data Exchange (ETDEWEB)

    Lamm, Matthias [AREVA GmbH, Erlangen (Germany). R and D; Hollands, Thorsten [Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS) gGmbH, Garching (Germany). Reactor Safety Research Div.

    2016-01-15

    Summary report on the Technical Sessions ''Know-how, New Build and Innovations'' and ''Operation and Safety of Nuclear Installations, Fuel SA: WASA-BOSS + CESAM'' of the 46{sup th} Annual Conference on Nuclear Technology (AMNT 2015) held in Berlin, 5 to 7 May 2015. Other Sessions of AMNT 2015 have been covered in atw 7 to 12 (2015) and will be covered in further issues of atw.

  18. Clindamycin Topical

    Science.gov (United States)

    ... topical clindamycin.you should know that abrasive or medicated soaps and skin products that contain alcohol may ... in, tightly closed, and out of reach of children. Store it at room temperature and away from ...

  19. Tretinoin Topical

    Science.gov (United States)

    ... lotions, astringents, and perfumes); they can sting your skin, especially when you first use tretinoin.Do not use any other topical medications, especially benzoyl peroxide, salicylic acid (wart remover), and dandruff shampoos containing sulfur or ...

  20. Thirty-first annual gaseous electronic conference. A topical conference of the American Physical Socity. Program and abstracts. [Buffalo, New York, October 17--20, 1978

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-01-01

    This volume contains the program and abstracts of the conference. The following topics are included: metal vapor molecular lasers, magnetohydrodynamics, rare gas halide and nuclear pumped lasers, transfer mechanisms in arcs, kinetic processes in rare gas halide lasers, arcs and flows, XeF kinetics and lasers, fundamental processes in excimer lasers, electrode effects and vacuum arcs, electron and ion transport, ion interactions and mobilities, glow discharges, diagnostics and afterglows, dissociative recombination, electron ionization and excitation, rare gas excimers and group VI lasers, breakdown, novel laser pumping techniques, electrode-related discharge phenomena, photon interactions, attachment, plasma chemistry and infrared lasers, electron scattering, and reactions of excited species. (RWR)

  1. Topical anesthesia

    Directory of Open Access Journals (Sweden)

    Mritunjay Kumar

    2015-01-01

    Full Text Available Topical anesthetics are being widely used in numerous medical and surgical sub-specialties such as anesthesia, ophthalmology, otorhinolaryngology, dentistry, urology, and aesthetic surgery. They cause superficial loss of pain sensation after direct application. Their delivery and effectiveness can be enhanced by using free bases; by increasing the drug concentration, lowering the melting point; by using physical and chemical permeation enhancers and lipid delivery vesicles. Various topical anesthetic agents available for use are eutectic mixture of local anesthetics, ELA-max, lidocaine, epinephrine, tetracaine, bupivanor, 4% tetracaine, benzocaine, proparacaine, Betacaine-LA, topicaine, lidoderm, S-caine patch™ and local anesthetic peel. While using them, careful attention must be paid to their pharmacology, area and duration of application, age and weight of the patients and possible side-effects.

  2. Timing Is Everything: A Comparative Study of the Adjustment Process of Fall and Mid-Year Community College Transfer Students at a Public Four-Year University. Working Paper Series. Number 1-10

    Science.gov (United States)

    Peska, Scott F.

    2009-01-01

    This sequential mixed method study (Creswell, 2003) compared the adjustment process of community college transfer students who began in the fall to those who began mid-year, beginning with a quantitative phase and extending to a qualitative phase of data collection in the fall semester and repeating this same sequence of data gathering with…

  3. 2015 Fermilab Laboratory Directed Research & Development Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Wester, W. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

    2016-05-26

    The Fermi National Accelerator Laboratory (FNAL) is conducting a Laboratory Directed Research and Development (LDRD) program. Fiscal year 2015 represents the first full year of LDRD at Fermilab and includes seven projects approved mid-year in FY14 and six projects approved in FY15. One of the seven original projects has been completed just after the beginning of FY15. The implementation of LDRD at Fermilab is captured in the approved Fermilab 2015 LDRD Annual Program Plan. In FY15, the LDRD program represents 0.64% of Laboratory funding. The scope of the LDRD program at Fermilab will be established over the next couple of years where a portfolio of about 20 on-going projects representing approximately between 1% and 1.5% of the Laboratory funding is anticipated. This Annual Report focuses on the status of the current projects and provides an overview of the current status of LDRD at Fermilab.

  4. ASIST 2002 annual meeting

    CERN Multimedia

    Peek, R

    2003-01-01

    Review of discussions and presentations at the American Society for Information Science and Technology 2002 annual meeting. Topics covered included new models of scholarly publishing and the development of the semantic web (1 page).

  5. Annual review of computer science

    Energy Technology Data Exchange (ETDEWEB)

    Traub, J.F. (Columbia Univ., New York, NY (USA)); Grosz, B.J. (Harvard Univ., Cambridge, MA (USA)); Lampson, B.W. (Digital Equipment Corp. (US)); Nilsson, N.J. (Stanford Univ., CA (USA))

    1988-01-01

    This book contains the annual review of computer science. Topics covered include: Database security, parallel algorithmic techniques for combinatorial computation, algebraic complexity theory, computer applications in manufacturing, and computational geometry.

  6. Diclofenac Topical (osteoarthritis pain)

    Science.gov (United States)

    Diclofenac topical gel (Voltaren) is used to relieve pain from osteoarthritis (arthritis caused by a breakdown of the ... the knees, ankles, feet, elbows, wrists, and hands. Diclofenac topical liquid (Pennsaid) is used to relieve osteoarthritis pain ...

  7. Syntacticized topics in Kurmuk

    DEFF Research Database (Denmark)

    Andersen, Torben

    2015-01-01

    This article argues that Kurmuk, a little-described Western Nilotic language, is characterized by a syntacticized topic whose grammatical relation is variable. In this language, declarative clauses have as topic an obligatory preverbal NP which is either a subject, an object or an adjunct....... The grammatical relation of the topic is expressed by a voice-like inflection of the verb, here called orientation. While subject-orientation is morphologically unmarked, object-oriented and adjunct-oriented verbs are marked by a subject suffix or by a suffix indicating that the topic is not subject, and adjunct......-orientation differs from object-orientation by a marked tone pattern. Topic choice largely reflects information structure by indicating topic continuity. The topic also plays a crucial role in relative clauses and in clauses with contrastive constituent focus, in that objects and adjuncts can only be relativized...

  8. Women's Health Topics

    Science.gov (United States)

    ... Health Diabetes Healthy Aging Heart Health Mammograms Caregiving Menopause Pregnancy Safe Medication Use Other Topics like cosmetics and nutrition Other Resources womenshealth.gov Federal Citizen Information Center ...

  9. [Topical therapy of rosacea].

    Science.gov (United States)

    Schöfer, H

    2013-07-01

    Metronidazole and azelaic acid are the only topical medications approved for rosacea. All other topical treatments for rosacea and its special forms are used off-label. Topical steroids are not indicated in rosacea, because of their side effects (induction of steroid rosacea, high risk of facial skin atrophy, and high risk of rebound after cessation of therapy). Topical as well as systemic steroids are allowed only as initial and short term therapy for acute forms of rosacea (e.g. rosacea fulminans). Papular and pustular rosacea is the major indication for topical therapy. Sebaceous gland and connective tissue hyperplasia in glandular-hypertrophic rosacea as well as erythema in erythematous rosacea do not respond well to topical measures. A new active substance, the alpha-2-adrenoreceptor agonist brimonidine, will be approved soon for the topical treatment of erythema in rosacea. All severe forms of rosacea should initially be treated with a combination of topical and systemic agents. After improvement of the clinical symptoms, topical treatment alone is usually adequate to maintain the control.

  10. Topic Identification in Discourse

    CERN Document Server

    Chen, K

    1995-01-01

    This paper proposes a corpus-based language model for topic identification. We analyze the association of noun-noun and noun-verb pairs in LOB Corpus. The word association norms are based on three factors: 1) word importance, 2) pair co-occurrence, and 3) distance. They are trained on the paragraph and sentence levels for noun-noun and noun-verb pairs, respectively. Under the topic coherence postulation, the nouns that have the strongest connectivities with the other nouns and verbs in the discourse form the preferred topic set. The collocational semantics then is used to identify the topics from paragraphs and to discuss the topic shift phenomenon among paragraphs.

  11. Advanced Topics in Aerodynamics

    DEFF Research Database (Denmark)

    Filippone, Antonino

    1999-01-01

    "Advanced Topics in Aerodynamics" is a comprehensive electronic guide to aerodynamics,computational fluid dynamics, aeronautics, aerospace propulsion systems, design and relatedtechnology. We report data, tables, graphics, sketches,examples, results, photos, technical andscientific literature...

  12. Supplemental topics on voids

    Energy Technology Data Exchange (ETDEWEB)

    Rood, H.J.

    1988-09-01

    Several topics concerning voids are presented, supplementing the report of Rood (1988). The discovery of the Coma supercluster and void and the recognition of the cosmological significance of superclusters and voids are reviewed. Galaxy redshift surveys and redshift surveys for the Abell clusters and very distant objects are discussed. Solar system and extragalactic dynamics are examined. Also, topics for future observational research on voids are recommended. 50 references.

  13. Topical treatment of melasma

    Directory of Open Access Journals (Sweden)

    Bandyopadhyay Debabrata

    2009-01-01

    Full Text Available Melasma is a common hypermelanotic disorder affecting the face that is associated with considerable psychological impacts. The management of melasma is challenging and requires a long-term treatment plan. In addition to avoidance of aggravating factors like oral pills and ultraviolet exposure, topical therapy has remained the mainstay of treatment. Multiple options for topical treatment are available, of which hydroquinone (HQ is the most commonly prescribed agent. Besides HQ, other topical agents for which varying degrees of evidence for clinical efficacy exist include azelaic acid, kojic acid, retinoids, topical steroids, glycolic acid, mequinol, and arbutin. Topical medications modify various stages of melanogenesis, the most common mode of action being inhibition of the enzyme, tyrosinase. Combination therapy is the preferred mode of treatment for the synergism and reduction of untoward effects. The most popular combination consists of HQ, a topical steroid, and retinoic acid. Prolonged HQ usage may lead to untoward effects like depigmentation and exogenous ochronosis. The search for safer alternatives has given rise to the development of many newer agents, several of them from natural sources. Well-designed controlled clinical trials are needed to clarify their role in the routine management of melasma.

  14. TOPICAL TREATMENT OF MELASMA

    Science.gov (United States)

    Bandyopadhyay, Debabrata

    2009-01-01

    Melasma is a common hypermelanotic disorder affecting the face that is associated with considerable psychological impacts. The management of melasma is challenging and requires a long-term treatment plan. In addition to avoidance of aggravating factors like oral pills and ultraviolet exposure, topical therapy has remained the mainstay of treatment. Multiple options for topical treatment are available, of which hydroquinone (HQ) is the most commonly prescribed agent. Besides HQ, other topical agents for which varying degrees of evidence for clinical efficacy exist include azelaic acid, kojic acid, retinoids, topical steroids, glycolic acid, mequinol, and arbutin. Topical medications modify various stages of melanogenesis, the most common mode of action being inhibition of the enzyme, tyrosinase. Combination therapy is the preferred mode of treatment for the synergism and reduction of untoward effects. The most popular combination consists of HQ, a topical steroid, and retinoic acid. Prolonged HQ usage may lead to untoward effects like depigmentation and exogenous ochronosis. The search for safer alternatives has given rise to the development of many newer agents, several of them from natural sources. Well-designed controlled clinical trials are needed to clarify their role in the routine management of melasma. PMID:20101327

  15. Topical Drugs for Pain Relief

    Directory of Open Access Journals (Sweden)

    Anjali Srinivasan

    2015-03-01

    Full Text Available Topical therapy helps patients with oral and perioral pain problems such as ulcers, burning mouth syndrome, temporomandibular disorders, neuromas, neuropathies and neuralgias. Topical drugs used in the field of dentistry are topical anaesthetics, topical analgesics, topical antibiotics and topical corticosteroids. It provides symptomatic/curative effect. Topical drugs are easy to apply, avoids hepatic first pass metabolism and more sites specific. But it can only be used for medications that require low plasma concentrations to achieve a therapeutic effect.

  16. Topical Drugs for Pain Relief

    OpenAIRE

    Anjali Srinivasan; Prashanth Shenai; Laxmikanth Chatra; Veena KM; Prasanna Kumar Rao

    2015-01-01

    Topical therapy helps patients with oral and perioral pain problems such as ulcers, burning mouth syndrome, temporomandibular disorders, neuromas, neuropathies and neuralgias. Topical drugs used in the field of dentistry are topical anaesthetics, topical analgesics, topical antibiotics and topical corticosteroids. It provides symptomatic/curative effect. Topical drugs are easy to apply, avoids hepatic first pass metabolism and more sites specific. But it can only be used for medications that ...

  17. Implicit stage topics

    Directory of Open Access Journals (Sweden)

    Karen Lahousse

    2008-04-01

    Full Text Available Il a souvent été proposé que les éléments spatio-temporels en position initiale de phrase spécifient le cadre de l’événement dénoté par la proposition et ont une interprétation thématique ou topicale. Alors que les topiques spatio-temporels explicites ont souvent été étudiés, Erteschik-Schir (1997, 1999 propose l’idée que les topiques spatio-temporels, ou topiques scéniques (stage topics peuvent aussi être implicites.Dans cet article, nous offrons des arguments en faveur de la notion de topique scénique implicite. Nous montrons qu’un certain nombre de cas d’inversion nominale en français, une configuration syntaxique qui est favorisée par la présence d’un topique scénique explicite, s’expliquent par la présence d’un topique scénique implicite. Le fait que les topiques scéniques implicites interagissent avec la structure syntaxique de la même façon que les topiques scéniques explicites constitue un argument empirique en faveur de leur existence.It has often been proposed that sentence-initial spatio-temporal elements specify the frame in which the whole proposition takes place and are topical (i.e. thematic. Whereas considerable attention has been paid to explicit spatio-temporal topics, Erteschik-Shir (1997, 1999 argues that spatio-temporal topics, or stage topics, can also be implicit.In this article we provide evidence in favour of the notion of implicit stage topic. We show that a certain number of nominal inversion cases in French, a syntactic configuration which is triggered by the presence of an explicit stage topic, are explained by the presence of an implicit stage topic. The fact that implicit stage topics interact with syntactic structure the same way explicit stage topics do constitutes a strong empirical argument in favour of their existence.

  18. Characters and Topical Diversity

    DEFF Research Database (Denmark)

    Eriksson, Rune

    2014-01-01

    The purpose of this article is to contribute to our understanding of the difference between the bestseller and the non-bestseller in nonfiction. It is noticed that many bestsellers in nonfiction belongs to the sub-genre of creative nonfiction, but also that the topics in this kind of literature...... is largely ignored by the critics. Thus, the article tests how topics may work in creative nonfiction. Two Danish bestsellers belonging to the genre, Frank’s Mit smukke genom ( My Beautiful Genome), about genomics, and Buk-Swienty’s Slagtebænk Dybbøl ( ‘Slaughter-bench Dybbøl’), a history book, are chosen...... as cases and analysed using a slightly modified motif model by Johansen. The result is that in both books the main topic is treated from a double perspective, but also that six out of seven secondary topics, or motifs, are treated as well. It is concluded that also in a topical sense creative nonfiction...

  19. Topical ketoprofen patch.

    Science.gov (United States)

    Mazières, Bernard

    2005-01-01

    Although oral nonsteroidal anti-inflammatory drugs (NSAIDs) are effective in the treatment of a variety of acute and chronic pain conditions, their use may be associated with serious systemic adverse effects, particularly gastrointestinal disorders. In order to minimise the incidence of systemic events related to such agents, topical NSAIDs have been developed. Topical NSAIDs, applied as gels, creams or sprays, penetrate the skin, subcutaneous fatty tissue and muscle in amounts that are sufficient to exert a therapeutic effect on peripheral and central mechanisms in the absence of high plasma concentrations. Data indicate that topical NSAIDs are effective at relieving pain in a number of acute and chronic pain indications. This review article discusses the pharmacokinetics, efficacy and tolerability of a new formulation of ketoprofen available as a topical patch. The topical patch containing ketoprofen 100mg as the active principle has been developed using a novel delivery system that dispenses therapeutic doses of the drug directly to the site of injury. Pharmacokinetic data indicate that although plasma levels of ketoprofen are higher when the drug is administered as a patch versus a gel, the total systemic bioavailability of ketoprofen 100 mg administered via a patch is no more than 10% of that reported for ketoprofen 100 mg administered orally. Because the patch facilitates ketoprofen delivery over a 24-hour period, the drug remains continually present in the tissue subjacent to the site of application. High tissue but low plasma ketoprofen concentrations mean that while tissue concentrations are high enough to exert a therapeutic effect, plasma concentrations remain low enough to not result in systemic adverse events caused by elevated serum NSAID levels. Phase III clinical trials in patients with non-articular rheumatism and traumatic painful soft tissue injuries showed that the topical ketoprofen patch was significantly more effective than placebo at

  20. Eighteenth annual West Coast theoretical chemistry conference

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-05-01

    Abstracts are presented from the eighteenth annual west coast theoretical chemistry conference. Topics include molecular simulations; quasiclassical simulations of reactions; photodissociation reactions; molecular dynamics;interface studies; electronic structure; and semiclassical methods of reactive systems.

  1. Characters and Topical Diversity

    DEFF Research Database (Denmark)

    Eriksson, Rune

    2014-01-01

    The purpose of this article is to contribute to our understanding of the difference between the bestseller and the non-bestseller in nonfiction. It is noticed that many bestsellers in nonfiction belongs to the sub-genre of creative nonfiction, but also that the topics in this kind of literature i...

  2. Selected topics in magnetism

    CERN Document Server

    Gupta, L C

    1993-01-01

    Part of the ""Frontiers in Solid State Sciences"" series, this volume presents essays on such topics as spin fluctuations in Heisenberg magnets, quenching of spin fluctuations by high magnetic fields, and kondo effect and heavy fermions in rare earths amongst others.

  3. Contrastive topics decomposed

    Directory of Open Access Journals (Sweden)

    Michael Wagner

    2012-12-01

    Full Text Available The analysis of contrastive topics introduced in Büring 1997b and further developed in Büring 2003 relies on distinguishing two types of constituents that introduce alternatives: the sentence focus, which is marked by a FOC feature, and the contrastive topic, which is marked by a CT feature. A non-compositional rule of interpretation that refers to these features is used to derive a topic semantic value, a nested set of sets of propositions. This paper presents evidence for a correlation between the restrictive syntax of nested focus operators and the syntax of contrastive topics, a correlation which is unexpected under this analysis. A compositional analysis is proposed that only makes use of the flatter focus semantic values introduced by focus operators. The analysis aims at integrating insights from the original analysis while at the same time capturing the observed syntactic restrictions. http://dx.doi.org/10.3765/sp.5.8 BibTeX info

  4. Topics in Nonlinear Dynamics

    DEFF Research Database (Denmark)

    Mosekilde, Erik

    Through a significant number of detailed and realistic examples this book illustrates how the insights gained over the past couple of decades in the fields of nonlinear dynamics and chaos theory can be applied in practice. Aomng the topics considered are microbiological reaction systems, ecological...

  5. Transportation: Topic Paper E.

    Science.gov (United States)

    National Council on the Handicapped, Washington, DC.

    As one of a series of topic papers assessing federal laws and programs affecting persons with disabilities, this paper reviews the issue of transportation services. In the area of urban mass transit, four relevant pieces of legislation and public transportation accessibility regulations are cited, and cost issues are explored. Paratransit systems,…

  6. Topics for Mathematics Clubs.

    Science.gov (United States)

    Dalton, LeRoy C., Ed.; Snyder, Henry D., Ed.

    The ten chapters in this booklet cover topics not ordinarily discussed in the classroom: Fibonacci sequences, projective geometry, groups, infinity and transfinite numbers, Pascal's Triangle, topology, experiments with natural numbers, non-Euclidean geometries, Boolean algebras, and the imaginary and the infinite in geometry. Each chapter is…

  7. PREFACE: CEWQO Topical Issue CEWQO Topical Issue

    Science.gov (United States)

    Bozic, Mirjana; Man'ko, Margarita

    2009-09-01

    This topical issue of Physica Scripta collects selected peer-reviewed contributions based on invited and contributed talks and posters presented at the 15th Central European Workshop on Quantum Optics (CEWQO) which took place in Belgrade 29 May-3 June 2008 (http://cewqo08.phy.bg.ac.yu). On behalf of the whole community took place in Belgrade 29 May-3 June 2008 (http://cewqo08.phy.bg.ac.yu, cewqo08.phy.bg.ac.yu). On behalf of the whole community of the workshop, we thank the referees for their careful reading and useful suggestions which helped to improve all of the submitted papers. A brief description of CEWQO The Central European Workshop on Quantum Optics is a series of conferences started informally in Budapest in 1992. Sometimes small events transform into important conferences, as in the case of CEWQO. Professor Jozsef Janszky, from the Research Institute of Solid State Physics and Optics, is the founder of this series. Margarita Man'ko obtained the following information from Jozsef Janszky during her visit to Budapest, within the framework of cooperation between the Russian and Hungarian Academies of Sciences in 2005. He organized a small workshop on quantum optics in Budapest in 1992 with John Klauder as a main speaker. Then, bearing in mind that a year before Janszky himself was invited by Vladimir Buzek to give a seminar on the same topic in Bratislava, he decided to assign the name 'Central European Workshop on Quantum Optics', considering the seminar in Bratislava to be the first workshop and the one in Budapest the second. The third formal workshop took place in Bratislava in 1993 organized by Vladimir Buzek, then in 1994 (Budapest, by Jozsef Janszky), 1995 and 1996 (Budmerice, Slovakia, by Vladimir Buzek), 1997 (Prague, by Igor Jex), 1999 (Olomouc, Czech Republic, by Zdenek Hradil), 2000 (Balatonfüred, Hungary, by Jozsef Janszky ), 2001 (Prague, by Igor Jex), 2002 (Szeged, Hungary, by Mihaly Benedict), 2003 (Rostock,Germany, by Werner Vogel and

  8. Novel Topic Authorship Attribution

    Science.gov (United States)

    2011-03-01

    cross-validation, genre shift, vector projection, singular value decomposition, principal component analysis Unclassified Unclassified Unclassified...by eight students. Each student wrote a total of 24 documents in three different genres about three different topics. They found that compensating for...Baayen, H. Halteren, A. Neijt, and F. Tweedie, “Outside the cave of shadows: Using syntactic annotation to enhance authorship attribution,” Literary

  9. Topics in Operator Theory

    CERN Document Server

    Ball, Joseph A; Helton, JWilliam; Rodman, Leiba; Spitkovsky, Iiya

    2010-01-01

    This is the first volume of a collection of original and review articles on recent advances and new directions in a multifaceted and interconnected area of mathematics and its applications. It encompasses many topics in theoretical developments in operator theory and its diverse applications in applied mathematics, physics, engineering, and other disciplines. The purpose is to bring in one volume many important original results of cutting edge research as well as authoritative review of recent achievements, challenges, and future directions in the area of operator theory and its applications.

  10. Topics in field theory

    CERN Document Server

    Karpilovsky, G

    1989-01-01

    This monograph gives a systematic account of certain important topics pertaining to field theory, including the central ideas, basic results and fundamental methods.Avoiding excessive technical detail, the book is intended for the student who has completed the equivalent of a standard first-year graduate algebra course. Thus it is assumed that the reader is familiar with basic ring-theoretic and group-theoretic concepts. A chapter on algebraic preliminaries is included, as well as a fairly large bibliography of works which are either directly relevant to the text or offer supplementary material of interest.

  11. Hot topics for leadership development.

    Science.gov (United States)

    Bleich, Michael R

    2015-02-01

    Three areas stand out from a health systems perspective that should be on the development agenda for all leaders. These topics include population health, predictive analytics, and supply chain management. Together, these topics address access, quality, and cost management.

  12. Renewable energy annual 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    This report presents summary data on renewable energy consumption, the status of each of the primary renewable technologies, a profile of each of the associated industries, an analysis of topical issues related to renewable energy, and information on renewable energy projects worldwide. It is the second in a series of annual reports on renewable energy. The renewable energy resources included in the report are biomass (wood and ethanol); municipal solid waste, including waste-to-energy and landfill gas; geothermal; wind; and solar energy, including solar thermal and photovoltaic. The report also includes various appendices and a glossary.

  13. Topics in orbit equivalence

    CERN Document Server

    Kechris, Alexander S

    2004-01-01

    This volume provides a self-contained introduction to some topics in orbit equivalence theory, a branch of ergodic theory. The first two chapters focus on hyperfiniteness and amenability. Included here are proofs of Dye's theorem that probability measure-preserving, ergodic actions of the integers are orbit equivalent and of the theorem of Connes-Feldman-Weiss identifying amenability and hyperfiniteness for non-singular equivalence relations. The presentation here is often influenced by descriptive set theory, and Borel and generic analogs of various results are discussed. The final chapter is a detailed account of Gaboriau's recent results on the theory of costs for equivalence relations and groups and its applications to proving rigidity theorems for actions of free groups.

  14. Topics in atomic physics

    CERN Document Server

    Burkhardt, Charles E

    2006-01-01

    The study of atomic physics propelled us into the quantum age in the early twentieth century and carried us into the twenty-first century with a wealth of new and, in some cases, unexplained phenomena. Topics in Atomic Physics provides a foundation for students to begin research in modern atomic physics. It can also serve as a reference because it contains material that is not easily located in other sources. A distinguishing feature is the thorough exposition of the quantum mechanical hydrogen atom using both the traditional formulation and an alternative treatment not usually found in textbooks. The alternative treatment exploits the preeminent nature of the pure Coulomb potential and places the Lenz vector operator on an equal footing with other operators corresponding to classically conserved quantities. A number of difficult to find proofs and derivations are included as is development of operator formalism that permits facile solution of the Stark effect in hydrogen. Discussion of the classical hydrogen...

  15. APT accelerator. Topical report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence, G.; Rusthoi, D. [comp.] [ed.

    1995-03-01

    The Accelerator Production of Tritium (APT) project, sponsored by Department of Energy Defense Programs (DOE/DP), involves the preconceptual design of an accelerator system to produce tritium for the nation`s stockpile of nuclear weapons. Tritium is an isotope of hydrogen used in nuclear weapons, and must be replenished because of radioactive decay (its half-life is approximately 12 years). Because the annual production requirements for tritium has greatly decreased since the end of the Cold War, an alternative approach to reactors for tritium production, based on a linear accelerator, is now being seriously considered. The annual tritium requirement at the time this study was undertaken (1992-1993) was 3/8 that of the 1988 goal, usually stated as 3/8-Goal. Continued reduction in the number of weapons in the stockpile has led to a revised (lower) production requirement today (March, 1995). The production requirement needed to maintain the reduced stockpile, as stated in the recent Nuclear Posture Review (summer 1994) is approximately 3/16-Goal, half the previous level. The Nuclear Posture Review also requires that the production plant be designed to accomodate a production increase (surge) to 3/8-Goal capability within five years, to allow recovery from a possible extended outage of the tritium plant. A multi-laboratory team, collaborating with several industrial partners, has developed a preconceptual APT design for the 3/8-Goal, operating at 75% capacity. The team has presented APT as a promising alternative to the reactor concepts proposed for Complex-21. Given the requirements of a reduced weapons stockpile, APT offers both significant safety, environmental, and production-fexibility advantages in comparison with reactor systems, and the prospect of successful development in time to meet the US defense requirements of the 21st Century.

  16. 2014 Fermilab Laboratory Directoed Research & Development Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Wester, W. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

    2016-05-26

    After initiation by the Fermilab Laboratory Director, a team from the senior Laboratory leadership and a Laboratory Directed Research and Development (LDRD) Advisory Committee developed an implementation plan for LDRD at Fermilab for the first time. This implementation was captured in the approved Fermilab 2014 LDRD Program Plan and followed directions and guidance from the Department of Energy (DOE) order, DOE O 413.2B, a “Roles, Responsibilities, and Guidelines, …” document, and examples of best practices at other DOE Office of Science Laboratories. At Fermilab, a FY14 midyear Call for Proposals was issued. A LDRD Selection Committee evaluated those proposals that were received and provided a recommendation to the Laboratory Director who approved seven LDRD projects. This Annual Report focuses on the status of those seven projects and provides an overview of the current status of LDRD at Fermilab. The seven FY14 LDRD approved projects had a date of initiation late in FY14 such that this report reflects approximately six months of effort approximately through January 2015. The progress of these seven projects, the subsequent award of six additional new projects beginning in FY15, and preparations for the issuance of the FY16 Call for Proposals indicates that LDRD is now integrated into the overall annual program at Fermilab. All indications are that LDRD is improving the scientific and technical vitality of the Laboratory and providing new, novel, or cutting edge projects carried out at the forefront of science and technology and aligned with the mission and strategic visions of Fermilab and the Department of Energy.

  17. Dosimetry: an ARDENT topic

    CERN Multimedia

    CERN Bulletin

    2012-01-01

    The first annual ARDENT workshop took place in Vienna from 20 to 23 November. The workshop gathered together the Early-Stage Researchers (ESR) and their supervisors, plus other people involved from all the participating institutions.   “The meeting, which was organised with the local support of the Austrian Institute of Technology, was a nice opportunity for the ESRs to get together, meet each other, and present their research plans and some preliminary results of their work,” says Marco Silari, a member of CERN Radiation Protection Group and the scientist in charge of the programme. Two full days were devoted to a training course on radiation dosimetry, delivered by renowned experts. The workshop closed with a half-day visit to the MedAustron facility in Wiener Neustadt. ARDENT (Advanced Radiation Dosimetry European Network Training) is a Marie Curie ITN project funded under EU FP7 with €4 million. The project focuses on radiation dosimetry exploiting se...

  18. Advanced verification topics

    CERN Document Server

    Bhattacharya, Bishnupriya; Hall, Gary; Heaton, Nick; Kashai, Yaron; Khan Neyaz; Kirshenbaum, Zeev; Shneydor, Efrat

    2011-01-01

    The Accellera Universal Verification Methodology (UVM) standard is architected to scale, but verification is growing and in more than just the digital design dimension. It is growing in the SoC dimension to include low-power and mixed-signal and the system integration dimension to include multi-language support and acceleration. These items and others all contribute to the quality of the SOC so the Metric-Driven Verification (MDV) methodology is needed to unify it all into a coherent verification plan. This book is for verification engineers and managers familiar with the UVM and the benefits it brings to digital verification but who also need to tackle specialized tasks. It is also written for the SoC project manager that is tasked with building an efficient worldwide team. While the task continues to become more complex, Advanced Verification Topics describes methodologies outside of the Accellera UVM standard, but that build on it, to provide a way for SoC teams to stay productive and profitable.

  19. Topics in statistical mechanics

    Energy Technology Data Exchange (ETDEWEB)

    Elser, V.

    1984-05-01

    This thesis deals with four independent topics in statistical mechanics: (1) the dimer problem is solved exactly for a hexagonal lattice with general boundary using a known generating function from the theory of partitions. It is shown that the leading term in the entropy depends on the shape of the boundary; (2) continuum models of percolation and self-avoiding walks are introduced with the property that their series expansions are sums over linear graphs with intrinsic combinatorial weights and explicit dimension dependence; (3) a constrained SOS model is used to describe the edge of a simple cubic crystal. Low and high temperature results are derived as well as the detailed behavior near the crystal facet; (4) the microscopic model of the lambda-transition involving atomic permutation cycles is reexamined. In particular, a new derivation of the two-component field theory model of the critical behavior is presented. Results for a lattice model originally proposed by Kikuchi are extended with a high temperature series expansion and Monte Carlo simulation. 30 references.

  20. Superconcentration and related topics

    CERN Document Server

    Chatterjee, Sourav

    2014-01-01

    A certain curious feature of random objects, introduced by the author as “super concentration,” and two related topics, “chaos” and “multiple valleys,” are highlighted in this book. Although super concentration has established itself as a recognized feature in a number of areas of probability theory in the last twenty years (under a variety of names), the author was the first to discover and explore its connections with chaos and multiple valleys. He achieves a substantial degree of simplification and clarity in the presentation of these findings by using the spectral approach. Understanding the fluctuations of random objects is one of the major goals of probability theory and a whole subfield of probability and analysis, called concentration of measure, is devoted to understanding these fluctuations. This subfield offers a range of tools for computing upper bounds on the orders of fluctuations of very complicated random variables. Usually, concentration of measure is useful when more direct prob...

  1. Researching Distressing Topics

    Directory of Open Access Journals (Sweden)

    Sharon Jackson

    2013-05-01

    Full Text Available Qualitative researchers who explore sensitive topics may expose themselves to emotional distress. Consequently, researchers are often faced with the challenge of maintaining emotional equilibrium during the research process. However, discussion on the management of difficult emotions has occupied a peripheral place within accounts of research practice. With rare exceptions, the focus of published accounts is concentrated on the analysis of the emotional phenomena that emerge during the collection of primary research data. Hence, there is a comparative absence of a dialogue around the emotional dimensions of working with secondary data sources. This article highlights some of the complex ways in which emotions enter the research process during secondary analysis, and the ways in which we engaged with and managed emotional states such as anger, sadness, and horror. The concepts of emotional labor and emotional reflexivity are used to consider the ways in which we “worked with” and “worked on” emotion. In doing so, we draw on our collective experiences of working on two collaborative projects with ChildLine Scotland in which a secondary analysis was conducted on children’s narratives of distress, worry, abuse, and neglect.

  2. Discovering health topics in social media using topic models.

    Directory of Open Access Journals (Sweden)

    Michael J Paul

    Full Text Available By aggregating self-reported health statuses across millions of users, we seek to characterize the variety of health information discussed in Twitter. We describe a topic modeling framework for discovering health topics in Twitter, a social media website. This is an exploratory approach with the goal of understanding what health topics are commonly discussed in social media. This paper describes in detail a statistical topic model created for this purpose, the Ailment Topic Aspect Model (ATAM, as well as our system for filtering general Twitter data based on health keywords and supervised classification. We show how ATAM and other topic models can automatically infer health topics in 144 million Twitter messages from 2011 to 2013. ATAM discovered 13 coherent clusters of Twitter messages, some of which correlate with seasonal influenza (r = 0.689 and allergies (r = 0.810 temporal surveillance data, as well as exercise (r =  .534 and obesity (r =  -.631 related geographic survey data in the United States. These results demonstrate that it is possible to automatically discover topics that attain statistically significant correlations with ground truth data, despite using minimal human supervision and no historical data to train the model, in contrast to prior work. Additionally, these results demonstrate that a single general-purpose model can identify many different health topics in social media.

  3. The topical treatment of psoriasis.

    NARCIS (Netherlands)

    Kerkhof, P.C.M. van de; Vissers, W.H.P.M.

    2003-01-01

    According to the patients, improvement of efficacy, long-term safety and improvement of compliance are needed. The topical treatment has been innovated during the last decade. Most important are the introduction of two new classes of treatments: topical vitamin D(3) analogues and the retinoid tazaro

  4. Topics of Evolutionary Computation 2001

    DEFF Research Database (Denmark)

    Ursem, Rasmus Kjær

    This booklet contains the student reports from the course: Topics of Evolutionary Computation, Fall 2001, given by Thiemo Krink, Rene Thomsen and Rasmus K. Ursem......This booklet contains the student reports from the course: Topics of Evolutionary Computation, Fall 2001, given by Thiemo Krink, Rene Thomsen and Rasmus K. Ursem...

  5. Science to Support DOE Site Cleanup: The Pacific Northwest National Laboratory Environmental Management Science Program Awards - Fiscal Year 2000 Mid-Year Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    CD Carlson; SQ Bennett

    2000-07-25

    Pacific Northwest National Laboratory was awarded ten Environmental Management Science Program (EMSP) research grants in fiscal year 1996, six in fiscal year 1997, eight in fiscal year 1998, and seven in fiscal year 1999. All of the fiscal year 1996 award projects have been completed and will publish final reports, so their annual updates will not be included in this document. This section summarizes how each of the currently funded grants addresses significant US Department of Energy (DOE) cleanup issues, including those at the Hanford Site. The technical progress made to date in each of these research projects is addressed in more detail in the individual progress reports contained in this document. This research performed at PNNL is focused primarily in four areas: Tank Waste Remediation; Decontamination and Decommissioning; Spent Nuclear Fuel and Nuclear Materials; and Soil and Groundwater Cleanup.

  6. Mental Mechanisms for Topics Identification

    Directory of Open Access Journals (Sweden)

    Louis Massey

    2014-01-01

    Full Text Available Topics identification (TI is the process that consists in determining the main themes present in natural language documents. The current TI modeling paradigm aims at acquiring semantic information from statistic properties of large text datasets. We investigate the mental mechanisms responsible for the identification of topics in a single document given existing knowledge. Our main hypothesis is that topics are the result of accumulated neural activation of loosely organized information stored in long-term memory (LTM. We experimentally tested our hypothesis with a computational model that simulates LTM activation. The model assumes activation decay as an unavoidable phenomenon originating from the bioelectric nature of neural systems. Since decay should negatively affect the quality of topics, the model predicts the presence of short-term memory (STM to keep the focus of attention on a few words, with the expected outcome of restoring quality to a baseline level. Our experiments measured topics quality of over 300 documents with various decay rates and STM capacity. Our results showed that accumulated activation of loosely organized information was an effective mental computational commodity to identify topics. It was furthermore confirmed that rapid decay is detrimental to topics quality but that limited capacity STM restores quality to a baseline level, even exceeding it slightly.

  7. Pocosin Lakes National Wildlife Refuge : Annual Hunt Evaluation for 2011.

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes the activities and results of the annual deer hunt on Pocosin Lakes National Wildlife Refuge for fall 2011. Topics covered include hunt...

  8. Earth Sciences Division annual report 1981. [Lead abstract

    Energy Technology Data Exchange (ETDEWEB)

    1982-09-01

    Separate abstracts were prepared for the 59 papers of the 1981 annual report of the Earth Sciences Division at Lawrence Berkeley Laboratory. The general topics covered included nuclear waste isolation, geophysics and reservoir engineering, and geosciences. (KRM)

  9. Pocosin Lakes National Wildlife Refuge : Annual Hunt Evaluation for 2005.

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes the activities and results of the annual deer hunt on Pocosin Lakes National Wildlife Refuge for fall 2005. Topics covered include hunt...

  10. Pocosin Lakes National Wildlife Refuge : Annual Hunt Evaluation for 2007.

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes the activities and results of the annual deer hunt on Pocosin Lakes National Wildlife Refuge for fall 2007. Topics covered include hunt...

  11. Pocosin Lakes National Wildlife Refuge : Annual Hunt Evaluation for 2004.

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes the activities and results of the annual deer hunt on Pocosin Lakes National Wildlife Refuge for fall 2004. Topics covered include hunt...

  12. Pocosin Lakes National Wildlife Refuge : Annual Hunt Evaluation for 2010.

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes the activities and results of the annual deer hunt on Pocosin Lakes National Wildlife Refuge for fall 2010. Topics covered include hunt...

  13. Pocosin Lakes National Wildlife Refuge : Annual Hunt Evaluation for 2002.

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes the activities and results of the annual deer hunt on Pocosin Lakes National Wildlife Refuge for fall 2002. Topics covered include hunt...

  14. Pocosin Lakes National Wildlife Refuge : Annual Hunt Evaluation for 2008.

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes the activities and results of the annual deer hunt on Pocosin Lakes National Wildlife Refuge for fall 2008. Topics covered include hunt...

  15. Pocosin Lakes National Wildlife Refuge : Annual Hunt Evaluation for 2009.

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes the activities and results of the annual deer hunt on Pocosin Lakes National Wildlife Refuge for fall 2009. Topics covered include hunt...

  16. Pocosin Lakes National Wildlife Refuge : Annual Hunt Evaluation for 2003.

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes the activities and results of the annual deer hunt on Pocosin Lakes National Wildlife Refuge for fall 2003. Topics covered include hunt...

  17. Pocosin Lakes National Wildlife Refuge : Annual Hunt Evaluation for 2006.

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes the activities and results of the annual deer hunt on Pocosin Lakes National Wildlife Refuge for fall 2006. Topics covered include hunt...

  18. Spring School on Superstring Theory and Related Topics

    CERN Document Server

    2017-01-01

    ICTP's annual Spring School on Superstring Theory and Related Topics provides pedagogical treatment of these subjects through lectures by some of the world's top string theorists. The activity is intended for theoretical physicists or mathematicians with knowledge of quantum field theory, general relativity and string theory. It is organized in collaboration with the Asia Pacific Center for Theoretical Physics (APCTP) and the Italian Institute for Nuclear Physics (INFN).

  19. Erythromycin and Benzoyl Peroxide Topical

    Science.gov (United States)

    The combination of erythromycin and benzoyl peroxide is used to treat acne. Erythromycin and benzoyl peroxide are in a class of medications called topical antibiotics. The combination of erythromycin ...

  20. Clindamycin and Benzoyl Peroxide Topical

    Science.gov (United States)

    The combination of clindamycin and benzoyl peroxide is used to treat acne. Clindamycin and benzoyl peroxide are in a class of medications called topical antibiotics. The combination of clindamycin ...

  1. Safety and Health Topics: Asbestos

    Science.gov (United States)

    ... Videos E-Tools Safety and Health Topics / Asbestos Asbestos This page requires that javascript be enabled for ... Hazards and Toxic Substances Hazardous Waste What is asbestos? Asbestos is the name given to a group ...

  2. Linguistic Extensions of Topic Models

    Science.gov (United States)

    2010-09-01

    class of corpora and would help monolingual users to explore and understand multilingual corpora. In this chapter, we develop multilingual LDAWN, an... Multilingual Priors As in the case of a monolingual walk over the concept hierarchy, we want to provide guidance to the multilingual model as to which parts...topic models for new datasets, such as unaligned multilingual corpora, and combine topic models with other sources of information about documents’ context

  3. Topics of Bioengineering in Wikipedia

    Directory of Open Access Journals (Sweden)

    Vassia Atanassova

    2009-10-01

    Full Text Available The present report aims to give a snapshot of how topics from the field of bioengineering (bioinformatics, bioprocess systems, biomedical engineering, biotechnology, etc. are currently covered in the free electronic encyclopedia Wikipedia. It also offers insights and information about what Wikipedia is, how it functions, how and when to cite Wikipedian articles, if necessary. Several external wikis, devoted to topics of bioengineering, are also listed and reviewed.

  4. Topics in modern differential geometry

    CERN Document Server

    Verstraelen, Leopold

    2017-01-01

    A variety of introductory articles is provided on a wide range of topics, including variational problems on curves and surfaces with anisotropic curvature. Experts in the fields of Riemannian, Lorentzian and contact geometry present state-of-the-art reviews of their topics. The contributions are written on a graduate level and contain extended bibliographies. The ten chapters are the result of various doctoral courses which were held in 2009 and 2010 at universities in Leuven, Serbia, Romania and Spain.

  5. Planning Annual Shutdown Inspection for BFB Boiler

    OpenAIRE

    Sorsa, Tatu

    2014-01-01

    The goal of this thesis was to create an illustrative guidebook of annual inspection planning for BFB boiler to help power plant operator when planning of annual inspection is topical. This thesis was made for Andritz Oy and it is based on inspection reports and experiences of BFB boiler’s maintenance and inspection staff. In this thesis it is shown how to plan an annual inspection for BFB boiler and thesis gives good tools and hints for operator to manage inspection from the beginning ...

  6. Bonneville Power Administration 1998 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.

    1998-01-01

    This is the 1998 annual report to the President by the Administrator and Chief Executive Officer of the Bonneville Power Administration. The topics of the report include financial highlights, letter to the President, review of 1998, financial data, management`s discussion and analysis, performance measures, financial statements, BPA executives, BPA offices, BPA profile.

  7. Selecting a Topic in Public Speaking

    Institute of Scientific and Technical Information of China (English)

    刘玉霞

    2013-01-01

    The first step in speechmaking is choosing a topic, which will decide the success of the speech. In the paper, we are go⁃ing to discuss how to select a topic in public speaking, and we’ll mainly talk about the following: the speaker, the occasion and the audience, selecting a topic, specific methods for choosing a topic and available topics.

  8. Topical agents in burn care

    Directory of Open Access Journals (Sweden)

    Momčilović Dragan

    2002-01-01

    Full Text Available Introduction Understanding of fluid shifts and recognition of the importance of early and appropriate fluid replacement therapy have significantly reduced mortality in the early post burn period. After the bum patient successfully passes the resuscitation period, the burn wound represents the greatest threat to survival. History Since the dawn of civilization, man has been trying to find an agent which would help burn wounds heal, and at the same time, not harm general condition of the injured. It was not until the XX century, after the discovery of antibiotics, when this condition was fulfilled. In 1968, combining silver and sulfadiazine, fox made silver-sulfadiazine, which is a 1% hydro-soluble cream and a superior agent in topical treatment of burns today. Current topical agents None of the topical antimicrobial agents available today, alone or combined, have the characteristics of ideal prophylactic agents, but they eliminate colonization of burn wound, and invasive infections are infrequent. With an excellent spectrum of activity, low toxicity, and ease of application with minimal pain, silver-sulfadiazine is still the most frequently used topical agent. Conclusion The incidence of invasive infections and overall mortality have been significantly reduced after introduction of topical burn wound antimicrobial agents into practice. In most burn patients the drug of choice for prophylaxis is silver sulfadiazine. Other agents may be useful in certain clinical situations.

  9. Quantum mechanics II advanced topics

    CERN Document Server

    Rajasekar, S

    2015-01-01

    Quantum Mechanics II: Advanced Topics uses more than a decade of research and the authors’ own teaching experience to expound on some of the more advanced topics and current research in quantum mechanics. A follow-up to the authors introductory book Quantum Mechanics I: The Fundamentals, this book begins with a chapter on quantum field theory, and goes on to present basic principles, key features, and applications. It outlines recent quantum technologies and phenomena, and introduces growing topics of interest in quantum mechanics. The authors describe promising applications that include ghost imaging, detection of weak amplitude objects, entangled two-photon microscopy, detection of small displacements, lithography, metrology, and teleportation of optical images. They also present worked-out examples and provide numerous problems at the end of each chapter.

  10. Topical therapies in hyperhidrosis care.

    Science.gov (United States)

    Pariser, David M; Ballard, Angela

    2014-10-01

    Primary focal hyperhidrosis affects 3% of the US population; about the same number as psoriasis. More than half of these patients have primary focal axillary hyperhidrosis: sweating that is beyond what is anticipated or necessary for thermoregulation. Most topical therapies are based on aluminum salts, which work by a chemical reaction that forms plugs in the eccrine sweat ducts. Topical anticholinergics may also be used. Instruction on proper methods and timing of antiperspirants enhances effect and may be effective alone or in combination with other treatments in patients with hyperhidrosis.

  11. Topics in current aerosol research

    CERN Document Server

    Hidy, G M

    1971-01-01

    Topics in Current Aerosol Research deals with the fundamental aspects of aerosol science, with emphasis on experiment and theory describing highly dispersed aerosols (HDAs) as well as the dynamics of charged suspensions. Topics covered range from the basic properties of HDAs to their formation and methods of generation; sources of electric charges; interactions between fluid and aerosol particles; and one-dimensional motion of charged cloud of particles. This volume is comprised of 13 chapters and begins with an introduction to the basic properties of HDAs, followed by a discussion on the form

  12. Topics in millimeter wave technology

    CERN Document Server

    Button, Kenneth

    1988-01-01

    Topics in Millimeter Wave Technology, Volume 1 presents topics related to millimeter wave technology, including fin-lines and passive components realized in fin-lines, suspended striplines, suspended substrate microstrips, and modal power exchange in multimode fibers. A miniaturized monopulse assembly constructed in planar waveguide with multimode scalar horn feeds is also described. This volume is comprised of five chapters; the first of which deals with the analysis and synthesis techniques for fin-lines as well as the various passive components realized in fin-line. Tapers, discontinuities,

  13. Automatic Labelling of Topics with Neural Embeddings

    OpenAIRE

    Bhatia, Shraey; Lau, Jey Han; Baldwin, Timothy

    2016-01-01

    Topics generated by topic models are typically represented as list of terms. To reduce the cognitive overhead of interpreting these topics for end-users, we propose labelling a topic with a succinct phrase that summarises its theme or idea. Using Wikipedia document titles as label candidates, we compute neural embeddings for documents and words to select the most relevant labels for topics. Compared to a state-of-the-art topic labelling system, our methodology is simpler, more efficient, and ...

  14. Seven topics in perturbative QCD

    Energy Technology Data Exchange (ETDEWEB)

    Buras, A.J.

    1980-09-01

    The following topics of perturbative QCD are discussed: (1) deep inelastic scattering; (2) higher order corrections to e/sup +/e/sup -/ annihilation, to photon structure functions and to quarkonia decays; (3) higher order corrections to fragmentation functions and to various semi-inclusive processes; (4) higher twist contributions; (5) exclusive processes; (6) transverse momentum effects; (7) jet and photon physics.

  15. The Health Curriculum: 500 Topics.

    Science.gov (United States)

    Byrd, Oliver E.

    2001-01-01

    This 1958 paper divides 500 health topics into 20 categories: health as a social accomplishment/social problem; nutrition; physical fitness; mental health and disease; heredity/eugenics; infection/immunity; chronic and degenerative disease; substance abuse; skin care; vision, hearing, and speech; dental health; safety; physical environment; health…

  16. Topics in combinatorial pattern matching

    DEFF Research Database (Denmark)

    Vildhøj, Hjalte Wedel

    This dissertation studies problems in the general theme of combinatorial pattern matching. More specifically, we study the following topics: Longest Common Extensions. We revisit the longest common extension (LCE) problem, that is, preprocess a string T into a compact data structure that supports...

  17. The pharmacology of topical analgesics.

    Science.gov (United States)

    Barkin, Robert L

    2013-07-01

    Pain management of patients continues to pose challenges to clinicians. Given the multiple dimensions of pain--whether acute or chronic, mild, moderate, or severe, nociceptive or neuropathic--a multimodal approach may be needed. Fortunately, clinicians have an array of nonpharmacologic and pharmacologic treatment choices; however, each modality must be chosen carefully, because some often used oral agents are associated with safety and tolerability issues that restrict their use in certain patients. In particular, orally administered nonsteroidal antiinflammatory drugs, opioids, antidepressants, and anticonvulsants are known to cause systemic adverse effects in some patients. To address this problem, a number of topical therapies in various therapeutic classes have been developed to reduce systemic exposure and minimize the risks of patients developing adverse events. For example, topical nonsteroidal anti-inflammatory drug formulations produce a site-specific effect (ie, cyclo-oxygenase inhibition) while decreasing the systemic exposure that may lead to undesired effects in patients. Similarly, derivatives of acetylsalicylic acid (ie, salicylates) are used in topical analgesic formulations that do not significantly enter the patient's systemic circulation. Salicylates, along with capsaicin, menthol, and camphor, compose the counterirritant class of topical analgesics, which produce analgesia by activating and then desensitizing epidermal nociceptors. Additionally, patches and creams that contain the local anesthetic lidocaine, alone or co-formulated with other local anesthetics, are also used to manage patients with select acute and chronic pain states. Perhaps the most common topical analgesic modality is the cautious application of cutaneous cold and heat. Such treatments may decrease pain not by reaching the target tissue through systemic distribution, but by acting more directly on the affected tissue. Despite the tolerability benefits associated with avoiding

  18. Annual review in automatic programming

    CERN Document Server

    Goodman, Richard

    2014-01-01

    Annual Review in Automatic Programming focuses on the techniques of automatic programming used with digital computers. Topics covered range from the design of machine-independent programming languages to the use of recursive procedures in ALGOL 60. A multi-pass translation scheme for ALGOL 60 is described, along with some commercial source languages. The structure and use of the syntax-directed compiler is also considered.Comprised of 12 chapters, this volume begins with a discussion on the basic ideas involved in the description of a computing process as a program for a computer, expressed in

  19. A randomized clinical trial on arresting dentin caries in preschool children by topical fluorides

    OpenAIRE

    Duangthip, Duangporn

    2015-01-01

    Introduction: Silver diammine fluoride (SDF) has been found to be effective in preventing and arresting dental caries in children. The annual or semi-annual application of SDF may not be practical in migratory populations or effective high caries risk patients. So far, no data are available about the effectiveness of intensive fluoride treatment in arresting dental caries in primary teeth. Objectives: This study aimed to compare the effectiveness of three topical fluoride application prot...

  20. Hot topics in functional neuroradiology.

    Science.gov (United States)

    Faro, S H; Mohamed, F B; Helpern, J A; Jensen, J H; Thulborn, K R; Atkinson, I C; Sair, H I; Mikulis, D J

    2013-12-01

    Functional neuroradiology represents a relatively new and ever-growing subspecialty in the field of neuroradiology. Neuroradiology has evolved beyond anatomy and basic tissue signal characteristics and strives to understand the underlying physiologic processes of central nervous system disease. The American Society of Functional Neuroradiology sponsors a yearly educational and scientific meeting, and the educational committee was asked to suggest a few cutting-edge functional neuroradiology techniques (hot topics). The following is a review of several of these topics and includes "Diffusion Tensor Imaging of the Pediatric Spinal Cord"; "Diffusional Kurtosis Imaging"; "From Standardization to Quantification: Beyond Biomarkers toward Bioscales as Neuro MR Imaging Surrogates of Clinical End Points"; Resting-State Functional MR Imaging"; and "Current Use of Cerebrovascular Reserve Imaging."

  1. Retapamulin: A newer topical antibiotic

    Directory of Open Access Journals (Sweden)

    D Dhingra

    2013-01-01

    Full Text Available Impetigo is a common childhood skin infection. There are reports of increasing drug resistance to the currently used topical antibiotics including fusidic acid and mupirocin. Retapamulin is a newer topical agent of pleuromutilin class approved by the Food and Drug Administration for treatment of impetigo in children and has been recently made available in the Indian market. It has been demonstrated to have low potential for the development of antibacterial resistance and a high degree of potency against poly drug resistant Gram-positive bacteria found in skin infections including Staphylococcus aureus strains. The drug is safe owing to low systemic absorption and has only minimal side-effect of local irritation at the site of application.

  2. Do scientists trace hot topics?

    Science.gov (United States)

    Wei, Tian; Li, Menghui; Wu, Chensheng; Yan, Xiao-Yong; Fan, Ying; Di, Zengru; Wu, Jinshan

    2013-01-01

    Do scientists follow hot topics in their scientific investigations? In this paper, by performing analysis to papers published in the American Physical Society (APS) Physical Review journals, it is found that papers are more likely to be attracted by hot fields, where the hotness of a field is measured by the number of papers belonging to the field. This indicates that scientists generally do follow hot topics. However, there are qualitative differences among scientists from various countries, among research works regarding different number of authors, different number of affiliations and different number of references. These observations could be valuable for policy makers when deciding research funding and also for individual researchers when searching for scientific projects.

  3. Topics on nonlinear generalized functions

    CERN Document Server

    Colombeau, J F

    2011-01-01

    The aim of this paper is to give the text of a recent introduction to nonlinear generalized functions exposed in my talk in the congress gf2011, which was asked by several participants. Three representative topics were presented: two recalls "Nonlinear generalized functions and their connections with distribution theory", "Examples of applications", and a recent development: "Locally convex topologies and compactness: a functional analysis of nonlinear generalized functions".

  4. Topical Ocular Delivery of NSAIDs

    OpenAIRE

    Ahuja, Munish; Avinash S Dhake; Sharma, Surendra K; Dipak K Majumdar

    2008-01-01

    In ocular tissue, arachidonic acid is metabolized by cyclooxygenase to prostaglandins which are the most important lipid derived mediators of inflammation. Presently nonsteroidal anti-inflammatory drugs (NSAIDs) which are cyclooxygenase (COX) inhibitors are being used for the treatment of inflammatory disorders. NSAIDs used in ophthalmology, topically, are salicylic-, indole acetic-, aryl acetic-, aryl propionic- and enolic acid derivatives. NSAIDs are weak acids with pKa mostly between 3.5 a...

  5. Topic Detection in Online Chat

    Science.gov (United States)

    2009-09-01

    including the time for reviewing instruction, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the...you. “ … Of making many books there is no end, and much study is a weariness of the flesh.” Ecclesiastes 12:12 , ESV xvi THIS PAGE INTENTIONALLY...topic detection," Online Information Review , vol. 30, pp. 496–516, 2006. [2] D. Jurafsky and J. H. Martin, Speech and Language Processing : An

  6. Probabilistic analysis and related topics

    CERN Document Server

    Bharucha-Reid, A T

    1983-01-01

    Probabilistic Analysis and Related Topics, Volume 3 focuses on the continuity, integrability, and differentiability of random functions, including operator theory, measure theory, and functional and numerical analysis. The selection first offers information on the qualitative theory of stochastic systems and Langevin equations with multiplicative noise. Discussions focus on phase-space evolution via direct integration, phase-space evolution, linear and nonlinear systems, linearization, and generalizations. The text then ponders on the stability theory of stochastic difference systems and Marko

  7. Stochastic Analysis and Related Topics

    CERN Document Server

    Ustunel, Ali

    1988-01-01

    The Silvri Workshop was divided into a short summer school and a working conference, producing lectures and research papers on recent developments in stochastic analysis on Wiener space. The topics treated in the lectures relate to the Malliavin calculus, the Skorohod integral and nonlinear functionals of white noise. Most of the research papers are applications of these subjects. This volume addresses researchers and graduate students in stochastic processes and theoretical physics.

  8. Hot topics from the Tevatron

    Energy Technology Data Exchange (ETDEWEB)

    Glenzinski, D.; /Fermilab

    2008-01-01

    The Tevatron Run-II began in March 2001. To date, both the CDF and D0 experiments have collected 1 fb{sup -1} of data each. The results obtained from this data set were summarized at this conference in 39 parallel session presentations covering a wide range of topics. The author summarizes the most important of those results here and comments on some of the prospects for the future.

  9. Probabilistic analysis and related topics

    CERN Document Server

    Bharucha-Reid, A T

    1979-01-01

    Probabilistic Analysis and Related Topics, Volume 2 focuses on the integrability, continuity, and differentiability of random functions, as well as functional analysis, measure theory, operator theory, and numerical analysis.The selection first offers information on the optimal control of stochastic systems and Gleason measures. Discussions focus on convergence of Gleason measures, random Gleason measures, orthogonally scattered Gleason measures, existence of optimal controls without feedback, random necessary conditions, and Gleason measures in tensor products. The text then elaborates on an

  10. Proceedings from the 5th annual international society for musculoskeletal imaging in rheumatology annual conference

    DEFF Research Database (Denmark)

    Conaghan, Philip G; Østergaard, Mikkel; D'Agostino, Maria Antonietta;

    2013-01-01

    Since its inception, ISEMIR has held an annual education meeting highlighting the changes in the utilization of imaging tools for the management of rheumatic diseases. ISEMIR's international faculty and world-renowned experts have discussed these topics at a very high scientific level. The evolut...

  11. Topics and features of academic medical library tutorials.

    Science.gov (United States)

    Anderson, Rozalynd P; Wilson, Steven P; Yeh, Felicia; Phillips, Betty; Livingston, Mary Briget

    2008-01-01

    In a 2007 study, librarians at the University of South Carolina School of Medicine Library examined freely available online tutorials on academic medical library Web sites. The team identified tutorial topics, determined common design features, and assessed elements of active learning in library-created tutorials; the team also generated a list of third-party tutorials to which medical libraries link. This article updates the earlier study, describing changes and trends in tutorial content and design on medical libraries' Web sites; the project team plans to continue to track trends in tutorial development by repeating this study annually.

  12. AMNT 2014. Key Topic: Fuel, decommissioning and disposal - report. Pt. 1

    Energy Technology Data Exchange (ETDEWEB)

    Seipolt, Thomas [NUKEM Technologies Engineering Services GmbH, Alzenau (Germany); Weber, Stefan [GNS Gesellschaft fuer Nuklear-Service mbH, Essen (Germany); Kock, Ingo [Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS) GmbH, Koeln (Germany)

    2015-02-15

    Summary report on the following Topical Sessions of the Key Topic 'Fuel, Decommissioning and Disposal' of the Annual Conference on Nuclear Technology held in Frankfurt, 6 to 8 May 2014: - From Pilot Project to an Industrial Service (Thomas Seipolt); - Radioactive Waste Management - Experiences with Interim and Final Storage (Stefan Weber and Ingo Kock). The other Sessions of the Key Topics 'Reactor Operation, Safety', 'Competence, Innovation, Regulation' and 'Fuel, Decommissioning and Disposal' have been covered in atw 10 and 12 (2014), 1 (2015) and will be covered in further issues of atw.

  13. Annual conference SAEE 2008

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-07-01

    Technical and economic challenges of a 1 t CO{sub 2} society was the topic addressed by the 2008 annual conference of the Swiss Association for Energy Economics. One tonne of carbon dioxide per head and year as a long-term energy strategy is the theme of a presentation made by professor Konstantin Boulouchos from the Swiss Federal Institute of Technology ETH in Zurich, Switzerland. Professor Dr. Rainhard Madlener from the Institute for Future Energy Consumer Needs and Behaviour in Aachen, Germany, took a look at the one-ton CO{sub 2} vision as a focus for technical development. Professor Thomas F. Rutherford from the ETH presented an economic analysis of one-ton CO{sub 2} scenarios. Eduard Schumacher, former Chairman of the Board at the IWB utility in Basel, Switzerland, presented examples of how energy policy can be implemented, using the IWB's activities as an example. Hansruedi Kunz, Head of the Energy Department in the Building Department of the Canton of Zurich discussed the chances offered and the problems posed by the implementation of measures that are to lead to the meeting of energy visions for the year 2050. A podium and discussion session completed the conference

  14. Topic extraction from adverbial clauses

    Directory of Open Access Journals (Sweden)

    Carlos Rubio Alcalá

    2016-06-01

    Full Text Available This paper offers new data to support findings about Topic extraction from adverbial clauses. Since such clauses are strong islands, they should not allow extraction of any kind, but we show here that if the appropriate conditions are met, Topics of the CLLD kind in Romance can move out of them. We propose that two conditions must be met for such movement to be possible: the first is that the adverbial clause must have undergone topicalisation in the first place; the second is that the adverbial clause is inherently topical from a semantic viewpoint. Contrast with other language families (Germanic, Quechua and Japanese is provided and the semantic implications of the proposal are briefly discussed. Keywords: topicalisation; Clitic Left Dislocation; syntactic islands; adverbial clauses Este artículo ofrece nuevos datos sobre la extracción de Tópicos desde oraciones subordinadas adverbiales. Dado que dichas oraciones son islas fuertes, no deberían permitir extracción de ningún tipo, pero mostramos que si se dan las condiciones apropiadas, los Tópicos del tipo CLLD en lenguas románicas pueden desplazarse fuera de ellas. Proponemos que se deben cumplir dos condiciones para que ese movimiento sea posible: la primera es que la propia subordinada adverbial se haya topicalizado en primer lugar; la segunda es que la subordinada adverbial sea inherentemente un Tópico desde el punto de vista semántico. Proporcionamos también algunos contrastes con otras familias lingüísticas (germánica, quechua y japonés y se discuten brevemente las implicaciones semánticas de la propuesta. Palabras clave: topicalización; dislocación a la izquierda con clítico; islas sintácticas; oraciones adverbiales

  15. Potential theory—selected topics

    CERN Document Server

    Aikawwa, Hiroaki

    1996-01-01

    The first part of these lecture notes is an introduction to potential theory to prepare the reader for later parts, which can be used as the basis for a series of advanced lectures/seminars on potential theory/harmonic analysis. Topics covered in the book include minimal thinness, quasiadditivity of capacity, applications of singular integrals to potential theory, L(p)-capacity theory, fine limits of the Nagel-Stein boundary limit theorem and integrability of superharmonic functions. The notes are written for an audience familiar with the theory of integration, distributions and basic functional analysis.

  16. Topics in atomic collision theory

    CERN Document Server

    Geltman, Sydney; Brueckner, Keith A

    1969-01-01

    Topics in Atomic Collision Theory originated in a course of graduate lectures given at the University of Colorado and at University College in London. It is recommended for students in physics and related fields who are interested in the application of quantum scattering theory to low-energy atomic collision phenomena. No attention is given to the electromagnetic, nuclear, or elementary particle domains. The book is organized into three parts: static field scattering, electron-atom collisions, and atom-atom collisions. These are in the order of increasing physical complexity and hence necessar

  17. IYA2009 NASA Programs: Midyear Status

    Science.gov (United States)

    Hasan, H.; Smith, D. A.

    2010-08-01

    NASA's Science Mission Directorate's (SMD) celebration of the International Year of Astronomy (IYA) 2009 was kicked off in January 2009 with a sneak preview of a multi-wavelength image of M101, and of other images from NASA's space science missions. Since then some of the exciting science generated by NASA's missions in astrophysics, planetary science and heliophysics, which has been given an IYA2009 flavor, has been made available to students, educators and the public worldwide. Some examples of the progress of NASA's programs are presented. The Visions of the Universe traveling exhibit of NASA images to public libraries around the country has been a spectacular success and is being extended to include more libraries. NASA IYA Student Ambassadors met at summer workshop and presented their projects. NASA's Afterschool Universe has provided IYA training to community-based organizations, while pre-launch teacher workshops associated with the Kepler and WISE missions have been designed to engage educators in the science of these missions. IYA activities have been associated with several missions launched this year. These include the Hubble Servicing Mission 4, Kepler, Herschel/Planck, and LCROSS. The NASA IYA website continues to be popular, getting visitors spanning a wide spectrum. NASA's IYA programs have captured the imagination of the public and continue to keep it engaged in the scientific exploration of the universe.

  18. Topical cidofovir for plantar warts.

    Science.gov (United States)

    Padilla España, Laura; Del Boz, Javier; Fernández Morano, Teresa; Arenas Villafranca, Javier; de Troya Martín, Magdalena

    2014-01-01

    Plantar warts are a common reason for dermatological consultations and their treatment can occasionally be a challenge. Plantar warts are benign lesions produced by the human papillomavirus (HPV) that often fail to respond to habitual treatment. Cidofovir is a potent antiviral drug that acts competitively, inhibiting viral DNA polymerase. Our aim was to assess the efficacy and safety of cidofovir cream for the treatment of viral plantar warts. We undertook a retrospective observational study of patients with plantar warts who received treatment with topical cidofovir between July 2008 and July 2011 at the Dermatology Service of the Hospital Costa del Sol, Marbella, Spain. Data about the rate of treatment response, the adverse effects, and recurrences, as well as the characteristics of the patient cohort, were recorded. We identified 35 patients who had received some previous treatment. The usual concentration was 3% (in 33 of 35 cases), applied twice a day (in 31 of 35 cases). A greater or lesser response was noted in 28 cases. There were two recurrences. Topical cidofovir seems to be a useful alternative for the therapeutic management of recalcitrant plantar common warts that fail to respond to usual treatment.

  19. Advice to travelers on topical insect repellent use against dengue mosquitoes in Far North Queensland, Australia.

    Science.gov (United States)

    Webb, Cameron E; Russell, Richard C

    2011-01-01

    Dengue outbreaks occur annually in Far North Queensland, Australia. Advice on topical insect repellents provided by health authorities rarely addresses the wide range of formulations and active ingredients currently registered for use in Australia. Recommendations on the use of registered products require review.

  20. Topical Pain Relievers May Cause Burns

    Science.gov (United States)

    ... Consumers Consumer Updates Topical Pain Relievers May Cause Burns Share Tweet Linkedin Pin it More sharing options ... rare, have ranged from mild to severe chemical burns with use of such brand-name topical muscle ...

  1. Human-competitive automatic topic indexing

    CERN Document Server

    Medelyan, Olena

    2009-01-01

    Topic indexing is the task of identifying the main topics covered by a document. These are useful for many purposes: as subject headings in libraries, as keywords in academic publications and as tags on the web. Knowing a document’s topics helps people judge its relevance quickly. However, assigning topics manually is labor intensive. This thesis shows how to generate them automatically in a way that competes with human performance. Three kinds of indexing are investigated: term assignment, a task commonly performed by librarians, who select topics from a controlled vocabulary; tagging, a popular activity of web users, who choose topics freely; and a new method of keyphrase extraction, where topics are equated to Wikipedia article names. A general two-stage algorithm is introduced that first selects candidate topics and then ranks them by significance based on their properties. These properties draw on statistical, semantic, domain-specific and encyclopedic knowledge. They are combined using a machine learn...

  2. Annual Report 2000; Rapport annuel 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This annual report gives the activities during the year 2000 and information about the General Direction of the Energy and Raw Materials (DGEMP) in France. The highlights of the year are discussed in the main following topics: public utilities, the Erika oil slick, the petroleum products prices increase, the energy efficiency national program, Eole 2005, the nuclear industry management. The french energy accounting, the publications and the organization of the DGEMP are also provided. (A.L.B.)

  3. Annual report 2009. Institute of Radiochemistry

    Energy Technology Data Exchange (ETDEWEB)

    Bernhard, G. (ed.)

    2010-07-01

    The annual report 2009 of the institute of radiochemistry covers the following topics: Part 1: Actinides (metals) in biosystems; Part 2: Actinides in waste repositories. The research projects were aimed to the basic knowledge about coordination of actinide element transport and transfer in the environment, bacteria influence on the immobilization of heavy metals in water and soils, microbial diversity in biofilms and clays, protein applications for biosensors, dominating processes of soil-liquid interfaces, sorption and surface complexation processes.

  4. Topics in Banach space theory

    CERN Document Server

    Albiac, Fernando

    2016-01-01

    This text provides the reader with the necessary technical tools and background to reach the frontiers of research without the introduction of too many extraneous concepts. Detailed and accessible proofs are included, as are a variety of exercises and problems. The two new chapters in this second edition are devoted to two topics of much current interest amongst functional analysts: Greedy approximation with respect to bases in Banach spaces and nonlinear geometry of Banach spaces. This new material is intended to present these two directions of research for their intrinsic importance within Banach space theory, and to motivate graduate students interested in learning more about them. This textbook assumes only a basic knowledge of functional analysis, giving the reader a self-contained overview of the ideas and techniques in the development of modern Banach space theory. Special emphasis is placed on the study of the classical Lebesgue spaces Lp (and their sequence space analogues) and spaces of continuous f...

  5. Topics in computational linear optimization

    DEFF Research Database (Denmark)

    Hultberg, Tim Helge

    2000-01-01

    of high quality solvers and the use of algebraic modelling systems to handle the communication between the modeller and the solver. This dissertation features four topics in computational linear optimization: A) automatic reformulation of mixed 0/1 linear programs, B) direct solution of sparse unsymmetric...... branch-and-bound algorithms depends heavily on the formulation of the problem. In seeking a better formulation, automatic reformulation employs a range of different techniques for obtaining an equivalent formulation of a given pure or mixed integer programming problem, such that the new formulation has...... a tighter LP-relaxation than the original formulation. The first paper surveys the use of automatic reformulation techniques for general mixed 0-1 linear programs. An implementation, Spiky, of a direct method for solving large sparse unsymmetric systems of linear equations is presented in the second paper...

  6. Topics in Open Topological Strings

    CERN Document Server

    Prudenziati, Andrea

    2010-01-01

    This thesis is based on some selected topics in open topological string theory which I have worked on during my Ph.D. It comprises an introductory part where I have focused on the points most needed for the later chapters, trading completeness for conciseness and clarity. Then, following [12], we discuss tadpole cancellation for topological strings where we mainly show how its implementation is needed for ensuring the same "odd" moduli decoupling encountered in the closed theory. Next we move to analyse how the open and closed effective field theories for the B model interact writing the complete Lagrangian. We first check it deriving some already known tree level amplitudes in term of target space quantities, and then we extend the recipe to new results; later we implement open closed duality from a target field theory perspective. This last subject is also analysed from a worldsheet point of view extending the analysis of [13]. Some ideas for future research are briefly reported.

  7. KEY TOPICS IN SPORTS MEDICINE

    Directory of Open Access Journals (Sweden)

    Amir Ali Narvani

    2006-12-01

    Full Text Available Key Topics in Sports Medicine is a single quick reference source for sports and exercise medicine. It presents the essential information from across relevant topic areas, and includes both the core and emerging issues in this rapidly developing field. It covers: 1 Sports injuries, rehabilitation and injury prevention, 2 Exercise physiology, fitness testing and training, 3 Drugs in sport, 4 Exercise and health promotion, 5 Sport and exercise for special and clinical populations, 6 The psychology of performance and injury. PURPOSE The Key Topics format provides extensive, concise information in an accessible, easy-to-follow manner. AUDIENCE The book is targeted the students and specialists in sports medicine and rehabilitation, athletic training, physiotherapy and orthopaedic surgery. The editors are authorities in their respective fields and this handbook depends on their extensive experience and knowledge accumulated over the years. FEATURES The book contains the information for clinical guidance, rapid access to concise details and facts. It is composed of 99 topics which present the information in an order that is considered logical and progressive as in most texts. Chapter headings are: 1. Functional Anatomy, 2. Training Principles / Development of Strength and Power, 3. Biomechanical Principles, 4. Biomechanical Analysis, 5. Physiology of Training, 6. Monitoring of Training Progress, 7. Nutrition, 8. Hot and Cold Climates, 9. Altitude, 10. Sport and Travelling, 11. Principles of Sport Injury Diagnosis, 12. Principles of Sport and Soft Tissue Management, 13. Principles of Physical Therapy and Rehabilitation, 14. Principles of Sport Injury Prevention, 15. Sports Psychology, 16. Team Sports, 17. Psychological Aspects of Injury in Sport, 18. Injury Repair Process, 19. Basic Biomechanics of Tissue Injury, 20. Plain Film Radiography in Sport, 21. Nuclear Medicine, 22. Diagnostic Ultrasound, 23. MRI Scan, 24. Other Imaging, 5. Head Injury, 26. Eye

  8. Synergetics introduction and advanced topics

    CERN Document Server

    Haken, Hermann

    2004-01-01

    This book is an often-requested reprint of two classic texts by H. Haken: "Synergetics. An Introduction" and "Advanced Synergetics". Synergetics, an interdisciplinary research program initiated by H. Haken in 1969, deals with the systematic and methodological approach to the rapidly growing field of complexity. Going well beyond qualitative analogies between complex systems in fields as diverse as physics, chemistry, biology, sociology and economics, Synergetics uses tools from theoretical physics and mathematics to construct an unifying framework within which quantitative descriptions of complex, self-organizing systems can be made. This may well explain the timelessness of H. Haken's original texts on this topic, which are now recognized as landmarks in the field of complex systems. They provide both the beginning graduate student and the seasoned researcher with solid knowledge of the basic concepts and mathematical tools. Moreover, they admirably convey the spirit of the pioneering work by the founder of ...

  9. Credibility improves topical blog post retrieval

    NARCIS (Netherlands)

    Weerkamp, W.; de Rijke, M.

    2008-01-01

    Topical blog post retrieval is the task of ranking blog posts with respect to their relevance for a given topic. To improve topical blog post retrieval we incorporate textual credibility indicators in the retrieval process. We consider two groups of indicators: post level (determined using informati

  10. Neutron transport simulation (selected topics)

    Science.gov (United States)

    Vaz, P.

    2009-10-01

    Neutron transport simulation is usually performed for criticality, power distribution, activation, scattering, dosimetry and shielding problems, among others. During the last fifteen years, innovative technological applications have been proposed (Accelerator Driven Systems, Energy Amplifiers, Spallation Neutron Sources, etc.), involving the utilization of intermediate energies (hundreds of MeV) and high-intensity (tens of mA) proton accelerators impinging in targets of high Z elements. Additionally, the use of protons, neutrons and light ions for medical applications (hadrontherapy) impose requirements on neutron dosimetry-related quantities (such as kerma factors) for biologically relevant materials, in the energy range starting at several tens of MeV. Shielding and activation related problems associated to the operation of high-energy proton accelerators, emerging space-related applications and aircrew dosimetry-related topics are also fields of intense activity requiring as accurate as possible medium- and high-energy neutron (and other hadrons) transport simulation. These applications impose specific requirements on cross-section data for structural materials, targets, actinides and biologically relevant materials. Emerging nuclear energy systems and next generation nuclear reactors also impose requirements on accurate neutron transport calculations and on cross-section data needs for structural materials, coolants and nuclear fuel materials, aiming at improved safety and detailed thermal-hydraulics and radiation damage studies. In this review paper, the state-of-the-art in the computational tools and methodologies available to perform neutron transport simulation is presented. Proton- and neutron-induced cross-section data needs and requirements are discussed. Hot topics are pinpointed, prospective views are provided and future trends identified.

  11. Neutron transport simulation (selected topics)

    Energy Technology Data Exchange (ETDEWEB)

    Vaz, P. [Instituto Tecnologico e Nuclear, Estrada Nacional 10, P-2686-953 Sacavem (Portugal)], E-mail: pedrovaz@itn.pt

    2009-10-15

    Neutron transport simulation is usually performed for criticality, power distribution, activation, scattering, dosimetry and shielding problems, among others. During the last fifteen years, innovative technological applications have been proposed (Accelerator Driven Systems, Energy Amplifiers, Spallation Neutron Sources, etc.), involving the utilization of intermediate energies (hundreds of MeV) and high-intensity (tens of mA) proton accelerators impinging in targets of high Z elements. Additionally, the use of protons, neutrons and light ions for medical applications (hadrontherapy) impose requirements on neutron dosimetry-related quantities (such as kerma factors) for biologically relevant materials, in the energy range starting at several tens of MeV. Shielding and activation related problems associated to the operation of high-energy proton accelerators, emerging space-related applications and aircrew dosimetry-related topics are also fields of intense activity requiring as accurate as possible medium- and high-energy neutron (and other hadrons) transport simulation. These applications impose specific requirements on cross-section data for structural materials, targets, actinides and biologically relevant materials. Emerging nuclear energy systems and next generation nuclear reactors also impose requirements on accurate neutron transport calculations and on cross-section data needs for structural materials, coolants and nuclear fuel materials, aiming at improved safety and detailed thermal-hydraulics and radiation damage studies. In this review paper, the state-of-the-art in the computational tools and methodologies available to perform neutron transport simulation is presented. Proton- and neutron-induced cross-section data needs and requirements are discussed. Hot topics are pinpointed, prospective views are provided and future trends identified.

  12. 80th Annual Meeting of the Psychometric Society

    CERN Document Server

    Bolt, Daniel; Wang, Wen-Chung; Douglas, Jeffrey; Wiberg, Marie

    2016-01-01

    The research articles in this volume cover timely quantitative psychology topics, including new methods in item response theory, computerized adaptive testing, cognitive diagnostic modeling, and psychological scaling. Topics within general quantitative methodology include structural equation modeling, factor analysis, causal modeling, mediation, missing data methods, and longitudinal data analysis. These methods will appeal, in particular, to researchers in the social sciences. The 80th annual meeting took place in Beijing, China, between the 12th and 16th of July, 2014. Previous volumes to showcase work from the Psychometric Society’s Meeting are New Developments in Quantitative Psychology: Presentations from the 77th Annual Psychometric Society Meeting (Springer, 2013), Quantitative Psychology Research: The 78th Annual Meeting of the Psychometric Society (Springer, 2015), and Quantitative Psychology Research: The 79th Annual Meeting of the Psychometric Society, Wisconsin, USA, 2014 (Springer, 2015).

  13. 79th Annual Meeting of the Psychometric Society

    CERN Document Server

    Bolt, Daniel; Wang, Wen-Chung; Douglas, Jeffrey; Chow, Sy-Miin

    2015-01-01

    These research articles from the 79th Annual Meeting of the Psychometric Society (IMPS) cover timely quantitative psychology topics, including new methods in item response theory, computerized adaptive testing, cognitive diagnostic modeling, and psychological scaling. Topics within general quantitative methodology include structural equation modeling, factor analysis, causal modeling, mediation, missing data methods, and longitudinal data analysis. These methods will appeal, in particular, to researchers in the social sciences. The 79th annual meeting took place in Madison, WI between July 21nd and 25th, 2014. Previous volumes to showcase work from the Psychometric Society’s Meeting are New Developments in Quantitative Psychology: Presentations from the 77th Annual Psychometric Society Meeting (Springer, 2013) and Quantitative Psychology Research: The 78th Annual Meeting of the Psychometric Society  (Springer, 2015).

  14. Multilingual Topic Models for Unaligned Text

    CERN Document Server

    Boyd-Graber, Jordan

    2012-01-01

    We develop the multilingual topic model for unaligned text (MuTo), a probabilistic model of text that is designed to analyze corpora composed of documents in two languages. From these documents, MuTo uses stochastic EM to simultaneously discover both a matching between the languages and multilingual latent topics. We demonstrate that MuTo is able to find shared topics on real-world multilingual corpora, successfully pairing related documents across languages. MuTo provides a new framework for creating multilingual topic models without needing carefully curated parallel corpora and allows applications built using the topic model formalism to be applied to a much wider class of corpora.

  15. Identifying Topics in Microblogs Using Wikipedia.

    Science.gov (United States)

    Yıldırım, Ahmet; Üsküdarlı, Suzan; Özgür, Arzucan

    2016-01-01

    Twitter is an extremely high volume platform for user generated contributions regarding any topic. The wealth of content created at real-time in massive quantities calls for automated approaches to identify the topics of the contributions. Such topics can be utilized in numerous ways, such as public opinion mining, marketing, entertainment, and disaster management. Towards this end, approaches to relate single or partial posts to knowledge base items have been proposed. However, in microblogging systems like Twitter, topics emerge from the culmination of a large number of contributions. Therefore, identifying topics based on collections of posts, where individual posts contribute to some aspect of the greater topic is necessary. Models, such as Latent Dirichlet Allocation (LDA), propose algorithms for relating collections of posts to sets of keywords that represent underlying topics. In these approaches, figuring out what the specific topic(s) the keyword sets represent remains as a separate task. Another issue in topic detection is the scope, which is often limited to specific domain, such as health. This work proposes an approach for identifying domain-independent specific topics related to sets of posts. In this approach, individual posts are processed and then aggregated to identify key tokens, which are then mapped to specific topics. Wikipedia article titles are selected to represent topics, since they are up to date, user-generated, sophisticated articles that span topics of human interest. This paper describes the proposed approach, a prototype implementation, and a case study based on data gathered during the heavily contributed periods corresponding to the four US election debates in 2012. The manually evaluated results (0.96 precision) and other observations from the study are discussed in detail.

  16. The 23rd Annual Meeting of the European Tissue Repair Society (ETRS) in Reims, France

    NARCIS (Netherlands)

    Hoff, J.W. Von den; Agren, M.S.; Coulomb, B.; Eming, S.A.; Lataillade, J.J.

    2014-01-01

    The 23rd Annual Meeting of the European Tissue Repair Society, Reims, France, October 23 to 25, 2013 focused on tissue repair and regenerative medicine covering topics such as stem cells, biomaterials, tissue engineering, and burns.

  17. Topics in Number Theory Conference

    CERN Document Server

    Andrews, George; Ono, Ken

    1999-01-01

    From July 31 through August 3,1997, the Pennsylvania State University hosted the Topics in Number Theory Conference. The conference was organized by Ken Ono and myself. By writing the preface, I am afforded the opportunity to express my gratitude to Ken for beng the inspiring and driving force behind the whole conference. Without his energy, enthusiasm and skill the entire event would never have occurred. We are extremely grateful to the sponsors of the conference: The National Sci­ ence Foundation, The Penn State Conference Center and the Penn State Depart­ ment of Mathematics. The object in this conference was to provide a variety of presentations giving a current picture of recent, significant work in number theory. There were eight plenary lectures: H. Darmon (McGill University), "Non-vanishing of L-functions and their derivatives modulo p. " A. Granville (University of Georgia), "Mean values of multiplicative functions. " C. Pomerance (University of Georgia), "Recent results in primality testing. " C. ...

  18. Decision Point 1 Topical Report

    Energy Technology Data Exchange (ETDEWEB)

    Yablonsky, Al; Barsoumian, Shant; Legere, David

    2013-05-01

    This Topical Report addresses accomplishments achieved during Phase 2a of the SkyMine® Carbon Mineralization Pilot Project. The primary objectives of this project are to design, construct, and operate a system to capture CO2 from a slipstream of flue gas from a commercial coal-fired cement kiln, convert that CO2 to products having commercial value (i.e., beneficial use), show the economic viability of the CO2 capture and conversion process, and thereby advance the technology to the point of readiness for commercial scale demonstration and proliferation. The overall process is carbon negative, resulting in mineralization of CO2 that would otherwise be released into the atmosphere. The project will also substantiate market opportunities for the technology by sales of chemicals into existing markets, and identify opportunities to improve technology performance and reduce costs at the commercial scale. The project is being conducted in two phases. The primary objectives of Phase 1 were to elaborate proven SkyMine® process chemistry to commercial pilot-scale operation and complete the preliminary design for the pilot plant to be built and operated in Phase 2, complete a NEPA evaluation, and develop a comprehensive carbon life cycle analysis. The objective of the current Phase (2a) is to complete the detailed design of the pilot plant to be built in Phase 2b.

  19. Recent Advances In Topical Therapy In Dermatology

    Directory of Open Access Journals (Sweden)

    Mohan Thappa Devinder

    2003-01-01

    Full Text Available With changing times various newer topical agents are introduced in the field of dermatology. Tacrolimus and pimecrolimus are immunisuppressants, which are effective topically and are tried in the management of atopic dermatitis as well as other disorders including allergic contact dermatitis, atrophic lichen planus, pyoderma gangrenosum. Imiquimod, an immune response modifier, is presently in use for genital warts but has potentials as anti- tumour agent and in various other dermatological conditions when used topically. Tazarotene is a newer addition to the list of topical reginoids, which is effective in psoriasis and has better effect in combination with calcipotriene, phototherapy and topical costicosteroids. Tazarotene and adapelene are also effective in inflammatory acne. Calcipotriol, a vitamin D analogue has been introduced as a topical agent in the treatment of psoriasis. Steroid components are also developed recently which will be devoid of the side effects but having adequate anti-inflammatory effect. Topical photodynamic therapy has also a wide range of use in dermatology. Newer topical agents including cidofovir, capsaicin, topical sensitizers, topical antifungal agents for onychomycosis are also of use in clinical practice. Other promising developments include skin substitutes and growth factors for wound care.

  20. The 23rd Annual Meeting of the European Tissue Repair Society (ETRS) in Reims, France

    DEFF Research Database (Denmark)

    Von den Hoff, Johannes W; Ågren, Sven Per Magnus; Coulomb, Bernard;

    2014-01-01

    The 23rd Annual Meeting of the European Tissue Repair Society, Reims, France, October 23 to 25, 2013 focused on tissue repair and regenerative medicine covering topics such as stem cells, biomaterials, tissue engineering, and burns.......The 23rd Annual Meeting of the European Tissue Repair Society, Reims, France, October 23 to 25, 2013 focused on tissue repair and regenerative medicine covering topics such as stem cells, biomaterials, tissue engineering, and burns....

  1. Selected topics of fluid mechanics

    Science.gov (United States)

    Kindsvater, Carl E.

    1958-01-01

    the Euler, Froude, Reynolds, Weber, and Cauchy numbers are defined as essential tools for interpreting and using experimental data. The derivations of the energy and momentum equations are treated in detail. One-dimensional equations for steady nonuniform flow are developed, and the restrictions applicable to the equations are emphasized. Conditions of uniform and gradually varied flow are discussed, and the origin of the Chezy equation is examined in relation to both the energy and the momentum equations. The inadequacy of all uniform-flow equations as a means of describing gradually varied flow is explained. Thus, one of the definitive problems of river hydraulics is analyzed in the light of present knowledge. This report is the outgrowth of a series of short schools conducted during the spring and summer of 1953 for engineers of the Surface Water Branch, Water Resources Division, U. S. Geological Survey. The topics considered are essentially the same as the topics selected for inclusion in the schools. However, in order that they might serve better as a guide and outline for informal study, the arrangement of the writer's original lecture notes has been considerably altered. The purpose of the report, like the purpose of the schools which inspired it, is to build a simple but strong framework of the fundamentals of fluid mechanics. It is believed that this framework is capable of supporting a detailed analysis of most of the practical problems met by the engineers of the Geological Survey. It is hoped that the least accomplishment of this work will be to inspire the reader with the confidence and desire to read more of the recent and current technical literature of modern fluid mechanics.

  2. Topical ocular delivery of NSAIDs.

    Science.gov (United States)

    Ahuja, Munish; Dhake, Avinash S; Sharma, Surendra K; Majumdar, Dipak K

    2008-06-01

    In ocular tissue, arachidonic acid is metabolized by cyclooxygenase to prostaglandins which are the most important lipid derived mediators of inflammation. Presently nonsteroidal anti-inflammatory drugs (NSAIDs) which are cyclooxygenase (COX) inhibitors are being used for the treatment of inflammatory disorders. NSAIDs used in ophthalmology, topically, are salicylic-, indole acetic-, aryl acetic-, aryl propionic- and enolic acid derivatives. NSAIDs are weak acids with pKa mostly between 3.5 and 4.5, and are poorly soluble in water. Aqueous ophthalmic solutions of NSAIDs have been made using sodium, potassium, tromethamine and lysine salts or complexing with cyclodextrins/solubilizer. Ocular penetration of NSAID demands an acidic ophthalmic solution where cyclodextrin could prevent precipitation of drug and minimize its ocular irritation potential. The incompatibility of NSAID with benzalkonium chloride is avoided by using polysorbate 80, cyclodextrins or tromethamine. Lysine salts and alpha-tocopheryl polyethylene glycol succinate disrupt corneal integrity, and their use requires caution. Thus a nonirritating ophthalmic solution of NSAID could be formulated by dissolving an appropriate water-soluble salt, in the presence of cyclodextrin or tromethamine (if needed) in mildly acidified purified water (if stability permits) with or without benzalkonium chloride and polyvinyl alcohol. Amide prodrugs met with mixed success due to incomplete intraocular hydrolysis. Suspension and ocular inserts appear irritating to the inflamed eye. Oil drop may be a suitable option for insoluble drugs and ointment may be used for sustained effect. Recent studies showed that the use of colloidal nanoparticle formulations and the potent COX 2 inhibitor bromfenac may enhance NSAID efficacy in eye preparations.

  3. Usage-Oriented Topic Maps Building Approach

    Science.gov (United States)

    Ellouze, Nebrasse; Lammari, Nadira; Métais, Elisabeth; Ben Ahmed, Mohamed

    In this paper, we present a collaborative and incremental construction approach of multilingual Topic Maps based on enrichment and merging techniques. In recent years, several Topic Map building approaches have been proposed endowed with different characteristics. Generally, they are dedicated to particular data types like text, semi-structured data, relational data, etc. We note also that most of these approaches take as input monolingual documents to build the Topic Map. The problem is that the large majority of resources available today are written in various languages, and these resources could be relevant even to non-native speakers. Thus, our work is driven towards a collaborative and incremental method for Topic Map construction from textual documents available in different languages. To enrich the Topic Map, we take as input a domain thesaurus and we propose also to explore the Topic Map usage which means available potential questions related to the source documents.

  4. Tracking topic birth and death in LDA.

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, Andrew T.; Robinson, David Gerald

    2011-09-01

    Most topic modeling algorithms that address the evolution of documents over time use the same number of topics at all times. This obscures the common occurrence in the data where new subjects arise and old ones diminish or disappear entirely. We propose an algorithm to model the birth and death of topics within an LDA-like framework. The user selects an initial number of topics, after which new topics are created and retired without further supervision. Our approach also accommodates many of the acceleration and parallelization schemes developed in recent years for standard LDA. In recent years, topic modeling algorithms such as latent semantic analysis (LSA)[17], latent Dirichlet allocation (LDA)[10] and their descendants have offered a powerful way to explore and interrogate corpora far too large for any human to grasp without assistance. Using such algorithms we are able to search for similar documents, model and track the volume of topics over time, search for correlated topics or model them with a hierarchy. Most of these algorithms are intended for use with static corpora where the number of documents and the size of the vocabulary are known in advance. Moreover, almost all current topic modeling algorithms fix the number of topics as one of the input parameters and keep it fixed across the entire corpus. While this is appropriate for static corpora, it becomes a serious handicap when analyzing time-varying data sets where topics come and go as a matter of course. This is doubly true for online algorithms that may not have the option of revising earlier results in light of new data. To be sure, these algorithms will account for changing data one way or another, but without the ability to adapt to structural changes such as entirely new topics they may do so in counterintuitive ways.

  5. The treatment of rosacea with topical ivermectin.

    Science.gov (United States)

    Ali, S T; Alinia, H; Feldman, S R

    2015-04-01

    The treatment of rosacea is challenging because several pathophysiologic processes may be involved, including neurovascular dysregulation and alterations in innate immune status. Demodex mites may play a role in the latter mechanism. Topical ivermectin is a new therapeutic modality which demonstrates antiparasitic and anti-inflammatory properties. This article reviews published evidence related to the efficacy and safety of topical ivermectin. PubMed was utilized to search for key words "topical ivermectin", "ivermectin cream" and "rosacea". Three clinical trials were found that studied topical ivermectin as a treatment option for rosacea. Ivermectin was effective, safe and well tolerated.

  6. Annual report - ESCELSA - 1999; Relatorio anual - ESCELSA - 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    The annual report of 1999 of ESCELSA - Brazilian electric power company - introduces the next main topics: state of Espirito Santo; strategic focus; financial performance; relation with investors; energy sales; customers; quality; electric system; investments; people; resources; synergies; awards; outlook; social balancing; and patrimonial balancing.

  7. Annual report - ENERSUL - 1999; Relatorio anual - ENERSUL - 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    The annual report of ENERSUL - Brazilian electric power distribution company - introduces the following main topics: Outlook for the State of Mato Grosso do Sul; strategic focus; financial performance; relation with investors; energy sold; capacity increases; customers; customers; energy balance; performance and quality; electric system; investments; people; human resources; synergies; awards; workplace safety; social balance; and patrimonial balance.

  8. Total 2004 annual report; TOTAL 2004 rapport annuel

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This annual report of the Group Total brings information and economic data on the following topics, for the year 2004: the corporate governance, the corporate social responsibility, the shareholder notebook, the management report, the activities, the upstream (exploration and production) and downstream (refining and marketing) operating, chemicals and other matters. (A.L.B.)

  9. ELETRONUCLEAR - Annual report - 1997; ELETRONUCLEAR - Relatorio anual - 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-07-01

    The annual activities report of 1997 of ELETRONUCLEAR - Brazilian company responsible by the electric power generation from the nuclear technology - introduces the next main topics: company vision and mission; energy production and commercialization; investments in the electric power generation; economic and financial situation; social balancing; and patrimonial balancing.

  10. Abstracts of Presentations--Seventh Annual 4S Meeting.

    Science.gov (United States)

    4S - Society for Social Studies of Science, 1982

    1982-01-01

    Presents abstracts of papers for the Seventh Annual Meeting of the Society for the Social Studies of Science. Topics include, among others, rhetoric of a scientific controversy; recombinant DNA; science and social justice; patent citation analysis; national need and peer-review process; and scientism, romanticism, and social realist images of…

  11. Nuffield Advanced Chemistry Courses Topic 10

    Science.gov (United States)

    Education in Science, 1975

    1975-01-01

    Presents an alternative series of investigations replacing the propanone-trichloromethane system (Topic 10) in the Nuffield A-Level course. A trichloromethane-ethyl ethanoate (acetate) system presented in four experiments give good results and removed the dangers arising from the other system. Topic 10 need not be re-written, just the replacement…

  12. Topic Maps Based Project Knowledge Management

    Institute of Scientific and Technical Information of China (English)

    Wu Xiaofan; Zhou Liang; Zhang Lei; Li Lingzhi; Ding Qiulin

    2006-01-01

    Based on topic maps, a preprocessing scheme using similarity comparision is presented and applied in knowledge management.Topic and occurrence-oriented merging algorithm is also introduced to implement knowledge integration for the sub-system. An Omnigator-supported example from an aeroaustic institute is utilised to validate the preprocessing method and the result indicates it can speed up the research schedule.

  13. Severe photosensitivity reaction induced by topical diclofenac

    OpenAIRE

    Akat, Pramod B.

    2013-01-01

    Albeit uncommon, photosensitivity reaction induced by diclofenac can be an unfortunate adverse reaction complicating its use as a topical analgesic. We here present a case of a patient who suffered such a reaction as a result of exposure to diclofenac, employed as a topical analgesic for low backache. The lesions healed with conservative management without extensive scarring or other complications.

  14. Fostering Topic Knowledge: Essential for Academic Writing

    Science.gov (United States)

    Proske, Antje; Kapp, Felix

    2013-01-01

    Several researchers emphasize the role of the writer's topic knowledge for writing. In academic writing topic knowledge is often constructed by studying source texts. One possibility to support that essential phase of the writing process is to provide interactive learning questions which facilitate the construction of an adequate situation…

  15. Prioritizing dermatoses: rationally selecting guideline topics

    NARCIS (Netherlands)

    Borgonjen, R.J.; Everdingen, J.J. van; Kerkhof, P.C.M. van de; Spuls, P.I.

    2015-01-01

    BACKGROUND: Clinical practice guideline (CPG) development starts with selecting appropriate topics, as resources to develop a guideline are limited. However, a standardized method for topic selection is commonly missing and the way different criteria are used to prioritize is not clear. OBJECTIVES:

  16. Severe photosensitivity reaction induced by topical diclofenac

    Directory of Open Access Journals (Sweden)

    Pramod B Akat

    2013-01-01

    Full Text Available Albeit uncommon, photosensitivity reaction induced by diclofenac can be an unfortunate adverse reaction complicating its use as a topical analgesic. We here present a case of a patient who suffered such a reaction as a result of exposure to diclofenac, employed as a topical analgesic for low backache. The lesions healed with conservative management without extensive scarring or other complications.

  17. Corneal staining after treatment with topical tetracycline

    NARCIS (Netherlands)

    R. Lapid-Gortzak; C.P. Nieuwendaal; A.R. Slomovic; L. Spanjaard

    2006-01-01

    Purpose: The purpose of this paper is to report a case of corneal staining after treatment with topical tetracycline. Methods: A patient with crystalline keratopathy caused by Streptococcus viridans after corneal transplantation was treated topically with tetracycline eye drops, based on results of

  18. Psoriasis: improving adherence to topical therapy.

    NARCIS (Netherlands)

    Feldman, S.R.; Horn, E.J.; Balkrishnan, R.; Basra, M.K.; Finlay, A.Y.; McCoy, D.; Menter, A.; Kerkhof, P.C.M. van de

    2008-01-01

    Topical therapy has an important role in psoriasis treatment. It is efficacious and has a favorable safety profile as demonstrated in clinical trials. However, poor treatment outcomes from topical therapy regimens likely result from poor adherence and ineffective use of the medication. The Internati

  19. Aerodynamics of wind turbines emerging topics

    CERN Document Server

    Amano, R S

    2014-01-01

    Focusing on Aerodynamics of Wind Turbines with topics ranging from Fundamental to Application of horizontal axis wind turbines, this book presents advanced topics including: Basic Theory for Wind turbine Blade Aerodynamics, Computational Methods, and Special Structural Reinforcement Technique for Wind Turbine Blades.

  20. Histiocytosis X: treatment with topical nitrogen mustard.

    Science.gov (United States)

    Berman, B; Chang, D L; Shupack, J L

    1980-07-01

    The case histories of two elderly patients with cutaneous histiocytosis X treated topically with nitrogen mustard are presented. The cutaneous lesions cleared within 2 to 3 weeks, and remission was maintained with daily topical administration of nitrogen mustard. The clinical impression of improvement was substantiated by light and electron microscopic studies prior to and after therapy.

  1. Generating focused topic-specific sentiment lexicons

    NARCIS (Netherlands)

    Jijkoun, V.; de Rijke, M.; Weerkamp, W.

    2010-01-01

    We present a method for automatically generating focused and accurate topic-specific subjectivity lexicons from a general purpose polarity lexicon that allow users to pin-point subjective on-topic information in a set of relevant documents. We motivate the need for such lexicons in the field of medi

  2. Correlated Topic Model for Web Services Ranking

    Directory of Open Access Journals (Sweden)

    Mustapha AZNAG

    2013-07-01

    Full Text Available With the increasing number of published Web services providing similar functionalities, it’s very tedious for a service consumer to make decision to select the appropriate one according to her/his needs. In this paper, we explore several probabilistic topic models: Probabilistic Latent Semantic Analysis (PLSA, Latent Dirichlet Allocation (LDA and Correlated Topic Model (CTM to extract latent factors from web service descriptions. In our approach, topic models are used as efficient dimension reduction techniques, which are able to capture semantic relationships between word-topic and topic-service interpreted in terms of probability distributions. To address the limitation of keywords-based queries, we represent web service description as a vector space and we introduce a new approach for discovering and ranking web services using latent factors. In our experiment, we evaluated our Service Discovery and Ranking approach by calculating the precision (P@n and normalized discounted cumulative gain (NDCGn.

  3. Topical antioxidants in radiodermatitis: a clinical review.

    Science.gov (United States)

    Kodiyan, Joyson; Amber, Kyle T

    2015-09-01

    Radiation-induced skin toxicity is the most prevalent side effect of radiation therapy. Not only does it have a significant effect on patients' quality of life, but it also results in poor follow-up and early termination of radiotherapy treatment. Several skin care practices and topical applications have been studied in the field of radiodermatitis, including skin washing, topical steroids, and mechanical skin barriers. Aside from these methods, many patients turn to complementary and alternative medicine for the prevention and treatment of radiodermatitis. Many of these alternative therapies are topically applied antioxidants. While the rationale behind the use of antioxidants in treating radiodermatitis is strong, clinical studies have been far less consistent. Even in large scale randomised controlled trials, findings have been limited by the inconsistent use of topical vehicles and placebos. In this article, the authors review the role of topical antioxidants to better help the practitioner navigate through different available skin directed antioxidants.

  4. Annual Statistical Supplement, 2015

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2015 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  5. Annual Statistical Supplement, 2002

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2002 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  6. Annual Statistical Supplement, 2014

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2014 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  7. Annual Statistical Supplement, 2000

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2000 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  8. Annual Statistical Supplement, 2010

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2010 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  9. Annual Statistical Supplement, 2009

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2009 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  10. Annual Statistical Supplement, 2004

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2004 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  11. Annual Statistical Supplement, 2011

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2011 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  12. Annual Statistical Supplement, 2006

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2006 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  13. Annual Statistical Supplement, 2001

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2001 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  14. Annual Statistical Supplement, 2003

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2003 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  15. Annual Statistical Supplement, 2005

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2005 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  16. Annual Statistical Supplement, 2008

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2008 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  17. Annual Statistical Supplement, 2007

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2007 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  18. 78th Annual Meeting of the Psychometric Society

    CERN Document Server

    Bolt, Daniel; Ark, L; Wang, Wen-Chung

    2015-01-01

    The 78th Annual Meeting of the Psychometric Society (IMPS) builds on the Psychometric Society's mission to share quantitative methods relevant to psychology. The chapters of this volume present cutting-edge work in the field. Topics include studies of item response theory, computerized adaptive testing, cognitive diagnostic modeling, and psychological scaling. Additional psychometric topics relate to structural equation modeling, factor analysis, causal modeling, mediation, missing data methods, and longitudinal data analysis, among others. The papers in this volume will be especially useful for researchers in the social sciences who use quantitative methods. Prior knowledge of statistical methods is recommended. The 78th annual meeting took place in Arnhem, The Netherlands between July 22nd and 26th, 2013. The previous volume to showcase work from the Psychometric Society’s Meeting is New Developments in Quantitative Psychology: Presentations from the 77th Annual Psychometric Society Meeting (Springer, 201...

  19. Topics on Electricity Transmission Pricing

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerndal, Mette

    2000-02-01

    Directorate (NVE). To prevent cross-subsidization, the largest state-owned firm was split to form Statkraft SF, Norway's largest generation company, and Statnett SF, the major transmission company. Statnett is also the system operator of the entire Norwegian power system. Many distribution companies, usually publicly owned, are still part of vertically integrated companies, but there is strict separation of the financial accounts for transmission/distribution and generation/marketing. Trading is accomplished through several channels. The largest organized market is the common Norwegian-Swedish pool, NordPool. NordPool ASA is owned by Statnett Marked (which is a subsidiary of Statnett) and the Swedish grid-company, Svenska Kraftnaet. NordPool also supports the Finnish and Danish markets, thus through cooperation with the grid-companies of Denmark (Eltra) and Finland (Fingrid), locational markets are provided in these countries as well. Unlike England and Wales, only part of actual production is traded on this market. In addition, independent brokers offer various energy-contracts and facilitate bilateral contracts. In 1998 22% of the energy was traded on the hourly day-ahead (spot) market of NordPool. NordPool also organizes a forward and futures market and settles contracts from the regulation market organized by Statnett. The regulation market is a realtime market used to settle imbalances in real time. In total, close to 30% of the energy traded is organized through NordPool, and this share is increasing year by year. The efficiency of the market is heavily affected by the operation and pricing of the transmission system, and the topic of this thesis concerns the interaction of the transmission network and the energy markets. Throughout, the findings are illustrated by means of simple examples. This is to enhance readability and intuition. Chapter 2 is devoted to power flow models, whereas chapter 3 provides an overview of models developed to efficiently coordinate the

  20. Topics in Electricity Transmission Pricing

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerndal, Mette

    2000-02-01

    Directorate (NVE). To prevent cross-subsidization, the largest state-owned firm was split to form Statkraft SF, Norway's largest generation company, and Statnett SF, the major transmission company. Statnett is also the system operator of the entire Norwegian power system. Many distribution companies, usually publicly owned, are still part of vertically integrated companies, but there is strict separation of the financial accounts for transmission/distribution and generation/marketing. Trading is accomplished through several channels. The largest organized market is the common Norwegian-Swedish pool, NordPool. NordPool ASA is owned by Statnett Marked (which is a subsidiary of Statnett) and the Swedish grid-company, Svenska Kraftnaet. NordPool also supports the Finnish and Danish markets, thus through cooperation with the grid-companies of Denmark (Eltra) and Finland (Fingrid), locational markets are provided in these countries as well. Unlike England and Wales, only part of actual production is traded on this market. In addition, independent brokers offer various energy-contracts and facilitate bilateral contracts. In 1998 22% of the energy was traded on the hourly day-ahead (spot) market of NordPool. NordPool also organizes a forward and futures market and settles contracts from the regulation market organized by Statnett. The regulation market is a realtime market used to settle imbalances in real time. In total, close to 30% of the energy traded is organized through NordPool, and this share is increasing year by year. The efficiency of the market is heavily affected by the operation and pricing of the transmission system, and the topic of this thesis concerns the interaction of the transmission network and the energy markets. Throughout, the findings are illustrated by means of simple examples. This is to enhance readability and intuition. To start with, chapter 2 is devoted to power flow models, whereas chapter 3 provides an overview of models developed to efficiently

  1. Topics in Electricity Transmission Pricing

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerndal, Mette

    2000-02-01

    Directorate (NVE). To prevent cross-subsidization, the largest state-owned firm was split to form Statkraft SF, Norway's largest generation company, and Statnett SF, the major transmission company. Statnett is also the system operator of the entire Norwegian power system. Many distribution companies, usually publicly owned, are still part of vertically integrated companies, but there is strict separation of the financial accounts for transmission/distribution and generation/marketing. Trading is accomplished through several channels. The largest organized market is the common Norwegian-Swedish pool, NordPool. NordPool ASA is owned by Statnett Marked (which is a subsidiary of Statnett) and the Swedish grid-company, Svenska Kraftnaet. NordPool also supports the Finnish and Danish markets, thus through cooperation with the grid-companies of Denmark (Eltra) and Finland (Fingrid), locational markets are provided in these countries as well. Unlike England and Wales, only part of actual production is traded on this market. In addition, independent brokers offer various energy-contracts and facilitate bilateral contracts. In 1998 22% of the energy was traded on the hourly day-ahead (spot) market of NordPool. NordPool also organizes a forward and futures market and settles contracts from the regulation market organized by Statnett. The regulation market is a realtime market used to settle imbalances in real time. In total, close to 30% of the energy traded is organized through NordPool, and this share is increasing year by year. The efficiency of the market is heavily affected by the operation and pricing of the transmission system, and the topic of this thesis concerns the interaction of the transmission network and the energy markets. Throughout, the findings are illustrated by means of simple examples. This is to enhance readability and intuition. To start with, chapter 2 is devoted to power flow models, whereas chapter 3 provides an overview of models developed to efficiently

  2. Topics on Electricity Transmission Pricing

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerndal, Mette

    2000-02-01

    Directorate (NVE). To prevent cross-subsidization, the largest state-owned firm was split to form Statkraft SF, Norway's largest generation company, and Statnett SF, the major transmission company. Statnett is also the system operator of the entire Norwegian power system. Many distribution companies, usually publicly owned, are still part of vertically integrated companies, but there is strict separation of the financial accounts for transmission/distribution and generation/marketing. Trading is accomplished through several channels. The largest organized market is the common Norwegian-Swedish pool, NordPool. NordPool ASA is owned by Statnett Marked (which is a subsidiary of Statnett) and the Swedish grid-company, Svenska Kraftnaet. NordPool also supports the Finnish and Danish markets, thus through cooperation with the grid-companies of Denmark (Eltra) and Finland (Fingrid), locational markets are provided in these countries as well. Unlike England and Wales, only part of actual production is traded on this market. In addition, independent brokers offer various energy-contracts and facilitate bilateral contracts. In 1998 22% of the energy was traded on the hourly day-ahead (spot) market of NordPool. NordPool also organizes a forward and futures market and settles contracts from the regulation market organized by Statnett. The regulation market is a realtime market used to settle imbalances in real time. In total, close to 30% of the energy traded is organized through NordPool, and this share is increasing year by year. The efficiency of the market is heavily affected by the operation and pricing of the transmission system, and the topic of this thesis concerns the interaction of the transmission network and the energy markets. Throughout, the findings are illustrated by means of simple examples. This is to enhance readability and intuition. Chapter 2 is devoted to power flow models, whereas chapter 3 provides an overview of models developed to efficiently coordinate the

  3. Digital Social Network Mining for Topic Discovery

    Science.gov (United States)

    Moradianzadeh, Pooya; Mohi, Maryam; Sadighi Moshkenani, Mohsen

    Networked computers are expanding more and more around the world, and digital social networks becoming of great importance for many people's work and leisure. This paper mainly focused on discovering the topic of exchanging information in digital social network. In brief, our method is to use a hierarchical dictionary of related topics and words that mapped to a graph. Then, with comparing the extracted keywords from the context of social network with graph nodes, probability of relation between context and desired topics will be computed. This model can be used in many applications such as advertising, viral marketing and high-risk group detection.

  4. Control of pain with topical plant medicines

    Institute of Scientific and Technical Information of China (English)

    James; David; Adams; Jr.; Xiaogang; Wang

    2015-01-01

    Pain is normally treated with oral nonsteroidal anti-inflammatory agents and opioids. These drugs are dangerous and are responsible for many hospitalizations and deaths. It is much safer to use topical preparations made from plants to treat pain, even severe pain. Topical preparations must contain compounds that penetrate the skin, inhibit pain receptors such as transient receptor potential cation channels and cyclooxygenase-2, to relieve pain. Inhibition of pain in the skin disrupts the pain cycle and avoids exposure of internal organs to large amounts of toxic compounds. Use of topical pain relievers has the potential to save many lives, decrease medical costs and improve therapy.

  5. Large scale topic modeling made practical

    DEFF Research Database (Denmark)

    Wahlgreen, Bjarne Ørum; Hansen, Lars Kai

    2011-01-01

    Topic models are of broad interest. They can be used for query expansion and result structuring in information retrieval and as an important component in services such as recommender systems and user adaptive advertising. In large scale applications both the size of the database (number of docume......Topic models are of broad interest. They can be used for query expansion and result structuring in information retrieval and as an important component in services such as recommender systems and user adaptive advertising. In large scale applications both the size of the database (number...... topics at par with a much larger case specific vocabulary....

  6. 25th International Workshop on Deep Inelastic Scattering and Related Topics

    CERN Document Server

    2017-01-01

    The 25th in an annual series of international workshops covering an eclectic mixture of material related to Quantum Chromodynamics and Deep Inelastic Scattering as well as a general survey of the hottest current topics in high energy physics. Much of the program is devoted to the most recent results from large experiments at BNL, CERN, DESY, FNAL, JLab, and KEK. Relevant theoretical advances are also covered in detail.

  7. Biotech in medicine--the topic of the Olten Meeting 2010.

    Science.gov (United States)

    Heinzelmann, Elsbeth

    2011-01-01

    Since 1998, the biotechnet--the national network of competence in biotech research--has been helping partners from industry to access excellence in R&D, giving them optimal support at low cost. Its annual 'Olten Meeting' is a dynamic hub for companies and research institutes as it highlights the latest trends in biotech. On November 24, 2010, the topical subject was biotech in medicine.

  8. Annual Energy Review, 2008

    Energy Technology Data Exchange (ETDEWEB)

    None

    2009-06-01

    The Annual Energy Review (AER) is the Energy Information Administration's (EIA) primary report of annual historical energy statistics. For many series, data begin with the year 1949. Included are statistics on total energy production, consumption, trade, and energy prices; overviews of petroleum, natural gas, coal, electricity, nuclear energy, renewable energy, and international energy; financial and environment indicators; and data unit conversions.

  9. Annual Report 1997

    Energy Technology Data Exchange (ETDEWEB)

    Golnik, N.; Mika, J.R.; Wieteska, K. [eds.

    1998-12-31

    This Annual Report of the Institute of Atomic Energy describes the results of the research works carried out at the Institute at 1997. As in the preceding years the authors of the individual scientific reports published in this Annual Report are fully responsible for their content and layout. The Report contains the information on other activities of the Institute as well. (author)

  10. Pulmonary Rehabilitation: MedlinePlus Health Topic

    Science.gov (United States)

    ... Related Issues Breathing and Relaxation (National Jewish Health) DANCE Your Way to Healthier Lungs (American Association for Respiratory Care) Exercises (National Jewish Health) Oxygen Therapy: MedlinePlus Health Topic (National Library of Medicine) Also ...

  11. Corneal Neurotoxicity Due to Topical Benzalkonium Chloride

    OpenAIRE

    Sarkar, Joy; Chaudhary, Shweta; Namavari, Abed; Ozturk, Okan; Chang, Jin-Hong; Yco, Lisette; Sonawane, Snehal; Khanolkar, Vishakha; Hallak, Joelle; Jain, Sandeep

    2012-01-01

    Topical application of benzalkonium chloride (BAK) to the eye causes dose-related corneal neurotoxicity. Corneal inflammation and reduction in aqueous tear production accompany neurotoxicity. Cessation of BAK treatment leads to recovery of corneal nerve density.

  12. Topical cidofovir for refractory verrucae in children.

    Science.gov (United States)

    Gupta, Monique; Bayliss, Susan J; Berk, David R

    2013-01-01

    Warts are common and are a challenge to treat in some children, especially immunocompromised children and those who fail or cannot tolerate salicylic acid preparations and cryotherapy. Cidofovir, a nucleotide analogue with antiviral activity, has demonstrated promising results when compounded into a topical form to treat refractory warts. We present a retrospective institutional review of 12 children with refractory verrucae treated with 1% to 3% topical cidofovir compounded in an unscented moisturizing cream, applied every other day to daily. In our institutional series, only three patients (25%) demonstrated complete clearance of their verrucae. An additional four patients (33%) demonstrated partial clearance. Our experience using topical cidofovir has been less successful than previous institutional reviews, possibly because we used a lower concentration and less-frequent dosing. More studies are needed to better characterize the efficacy, safety, and dosing of topical cidofovir for the treatment of refractory warts.

  13. Diabetes: MedlinePlus Health Topic

    Science.gov (United States)

    ... Foundation for Medical Education and Research) Prevention and Risk Factors Choose More than 50 Ways to Prevent Type ... Resources for Living Well (National Diabetes Education Program) Diabetic Diet: MedlinePlus Health Topic (National Library of Medicine) ...

  14. Teenage Pregnancy: MedlinePlus Health Topic

    Science.gov (United States)

    ... Tips for Parents to Help Their Children Avoid Teen Pregnancy (National Campaign to Prevent Teen and Unplanned Pregnancy) - PDF Living With Pregnancy and Nutrition: MedlinePlus Health Topic (National Library of Medicine) Also ...

  15. Mining Concurrent Topical Activity in Microblog Streams

    CERN Document Server

    Panisson, A; Quaggiotto, M; Cattuto, C

    2014-01-01

    Streams of user-generated content in social media exhibit patterns of collective attention across diverse topics, with temporal structures determined both by exogenous factors and endogenous factors. Teasing apart different topics and resolving their individual, concurrent, activity timelines is a key challenge in extracting knowledge from microblog streams. Facing this challenge requires the use of methods that expose latent signals by using term correlations across posts and over time. Here we focus on content posted to Twitter during the London 2012 Olympics, for which a detailed schedule of events is independently available and can be used for reference. We mine the temporal structure of topical activity by using two methods based on non-negative matrix factorization. We show that for events in the Olympics schedule that can be semantically matched to Twitter topics, the extracted Twitter activity timeline closely matches the known timeline from the schedule. Our results show that, given appropriate techn...

  16. Pain Relievers: MedlinePlus Health Topic

    Science.gov (United States)

    ... Physicians) Also in Spanish Medicines for Pain: From Osteoarthritis to Muscle Pain (National Center for Farmworker Health, ... Institutes of Health Page last updated on 16 March 2017 Topic last reviewed: 29 December 2016

  17. Hip Replacement: MedlinePlus Health Topic

    Science.gov (United States)

    ... damage. The most common cause of damage is osteoarthritis . Osteoarthritis causes pain, swelling, and reduced motion in your ... Institutes of Health Page last updated on 17 March 2017 Topic last reviewed: 31 August 2016

  18. MedlinePlus Health Topic Web Service

    Data.gov (United States)

    U.S. Department of Health & Human Services — A search-based Web service that provides access to disease, condition and wellness information via MedlinePlus health topic data in XML format. The service accepts...

  19. Sports Safety: MedlinePlus Health Topic

    Science.gov (United States)

    ... exercise injuries Returning to sports after a back injury Sports physical Related Health Topics Sports Fitness Sports Injuries Water Safety (Recreational) Languages Hmong (Hmoob) Russian (Русский) ...

  20. Helpful Contacts - Agency List By Topic

    Data.gov (United States)

    U.S. Department of Health & Human Services — A database of agencies listed by state and topic to provide you with contact information for specific organizations or help you get answers to your Medicare related...

  1. Pharmacogenetics of ophthalmic topical β-blockers

    OpenAIRE

    Sidjanin, Duska J.; McCarty, Catherine A.; Patchett, Richard; Smith, Edward; Wilke, Russell A.

    2008-01-01

    Glaucoma is the second leading cause of blindness worldwide. The primary glaucoma risk factor is elevated intraocular pressure. Topical β-blockers are affordable and widely used to lower intraocular pressure. Genetic variability has been postulated to contribute to interpersonal differences in efficacy and safety of topical β-blockers. This review summarizes clinically significant polymorphisms that have been identified in the β-adrenergic receptors (ADRB1, ADRB2 and ADRB3). The implications ...

  2. Topical steroid addiction in atopic dermatitis

    Directory of Open Access Journals (Sweden)

    Fukaya M

    2014-10-01

    Full Text Available Mototsugu Fukaya,1 Kenji Sato,2 Mitsuko Sato,3 Hajime Kimata,4 Shigeki Fujisawa,5 Haruhiko Dozono,6 Jun Yoshizawa,7 Satoko Minaguchi8 1Tsurumai Kouen Clinic, Nagoya, 2Department of Dermatology, Hannan Chuo Hospital, Osaka, 3Sato Pediatric Clinic, Osaka, 4Kimata Hajime Clinic, Osaka, 5Fujisawa Dermatology Clinic, Tokyo, 6Dozono Medical House, Kagoshima, 7Yoshizawa Dermatology Clinic, Yokohama, 8Department of Dermatology, Kounosu Kyousei Hospital, Saitama, Japan Abstract: The American Academy of Dermatology published a new guideline regarding topical therapy in atopic dermatitis in May 2014. Although topical steroid addiction or red burning skin syndrome had been mentioned as possible side effects of topical steroids in a 2006 review article in the Journal of the American Academy of Dermatology, no statement was made regarding this illness in the new guidelines. This suggests that there are still controversies regarding this illness. Here, we describe the clinical features of topical steroid addiction or red burning skin syndrome, based on the treatment of many cases of the illness. Because there have been few articles in the medical literature regarding this illness, the description in this article will be of some benefit to better understand the illness and to spur discussion regarding topical steroid addiction or red burning skin syndrome. Keywords: topical steroid addiction, atopic dermatitis, red burning skin syndrome, rebound, corticosteroid, eczema

  3. A Survey of Topic Modeling in Text Mining

    Directory of Open Access Journals (Sweden)

    Rubayyi Alghamdi

    2015-01-01

    Full Text Available Topic models provide a convenient way to analyze large of unclassified text. A topic contains a cluster of words that frequently occur together. A topic modeling can connect words with similar meanings and distinguish between uses of words with multiple meanings. This paper provides two categories that can be under the field of topic modeling. First one discusses the area of methods of topic modeling, which has four methods that can be considerable under this category. These methods are Latent semantic analysis (LSA, Probabilistic latent semantic analysis (PLSA, Latent Dirichlet allocation (LDA, and Correlated topic model (CTM. The second category is called topic evolution models, which model topics by considering an important factor time. In the second category, different models are discussed, such as topic over time (TOT, dynamic topic models (DTM, multiscale topic tomography, dynamic topic correlation detection, detecting topic evolution in scientific literature, etc.

  4. Annual General Canvass Statistics

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains annual quantities and value for all seafood products that are landed and sold by established seafood dealers and brokers in the Southeast...

  5. Annual Trapping Proposal 1985

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This Annual Trapping Plan for the 1984-1985 trapping season at Clarence Cannon NWR outlines rules and regulations for the trapping of beaver and muskrat on the...

  6. USRDS - Annual Data Report

    Data.gov (United States)

    U.S. Department of Health & Human Services — United States Renal Data System (USRDS) Annual Data Report Comprehensive statistics on chronic kidney disease and end-stage renal diseases in the United States...

  7. 2010 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    None

    2010-01-01

    This annual report includes: an overview of Western; approaches for future hydropower and transmission service; major achievements in FY 2010; FY 2010 customer Integrated Resource Planning, or IRP, survey; and financial data.

  8. Annual General Meeting

    CERN Multimedia

    Staff Association

    2014-01-01

      STAFF ASSOCIATION Our next annual general meeting will take place on : Thursday 22 May 2014 at 11:00 AM Building 40-S2-D01 For further information visit our website : https://indico.cern.ch/event/313124/

  9. Annual Adjustment Factors

    Data.gov (United States)

    Department of Housing and Urban Development — The Department of Housing and Urban Development establishes the rent adjustment factors - called Annual Adjustment Factors (AAFs) - on the basis of Consumer Price...

  10. SIS - Annual Catch Limit

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Annual Catch Limit (ACL) dataset within the Species Information System (SIS) contains information and data related to management reference points and catch data.

  11. TopicLens: Efficient Multi-Level Visual Topic Exploration of Large-Scale Document Collections.

    Science.gov (United States)

    Kim, Minjeong; Kang, Kyeongpil; Park, Deokgun; Choo, Jaegul; Elmqvist, Niklas

    2017-01-01

    Topic modeling, which reveals underlying topics of a document corpus, has been actively adopted in visual analytics for large-scale document collections. However, due to its significant processing time and non-interactive nature, topic modeling has so far not been tightly integrated into a visual analytics workflow. Instead, most such systems are limited to utilizing a fixed, initial set of topics. Motivated by this gap in the literature, we propose a novel interaction technique called TopicLens that allows a user to dynamically explore data through a lens interface where topic modeling and the corresponding 2D embedding are efficiently computed on the fly. To support this interaction in real time while maintaining view consistency, we propose a novel efficient topic modeling method and a semi-supervised 2D embedding algorithm. Our work is based on improving state-of-the-art methods such as nonnegative matrix factorization and t-distributed stochastic neighbor embedding. Furthermore, we have built a web-based visual analytics system integrated with TopicLens. We use this system to measure the performance and the visualization quality of our proposed methods. We provide several scenarios showcasing the capability of TopicLens using real-world datasets.

  12. Analyses of Research Topics in the Field of Informetrics Based on the Method of Topic Modeling

    Directory of Open Access Journals (Sweden)

    Sung-Chien Lin

    2014-07-01

    Full Text Available In this study, we used the approach of topic modeling to uncover the possible structure of research topics in the field of Informetrics, to explore the distribution of the topics over years, and to compare the core journals. In order to infer the structure of the topics in the field, the data of the papers published in the Journal of Informetricsand Scientometrics during 2007 to 2013 are retrieved from the database of the Web of Science as input of the approach of topic modeling. The results of this study show that when the number of topics was set to 10, the topic model has the smallest perplexity. Although data scopes and analysis methodsare different to previous studies, the generating topics of this study are consistent with those results produced by analyses of experts. Empirical case studies and measurements of bibliometric indicators were concerned important in every year during the whole analytic period, and the field was increasing stability. Both the two core journals broadly paid more attention to all of the topics in the field of Informetrics. The Journal of Informetricsput particular emphasis on construction and applications ofbibliometric indicators and Scientometrics focused on the evaluation and the factors of productivity of countries, institutions, domains, and journals.

  13. Topical treatment options for conjunctival neoplasms

    Directory of Open Access Journals (Sweden)

    Jonathan W Kim

    2008-10-01

    Full Text Available Jonathan W Kim, David H AbramsonOphthalmic Oncology Service, Memorial Sloan-Kettering Cancer Center, New York, NY, USAAbstract: Topical therapies offer a nonsurgical method for treating conjunctival tumors by delivering high drug concentrations to the ocular surface. Over the past ten years, topical agents have been used by investigators to treat various premalignant and malignant lesions of the conjunctiva, such as primary acquired melanosis with atypia, conjunctival melanoma, squamous intraepithelial neoplasia and squamous cell carcinoma of the conjunctiva, and pagetoid spread of the conjunctiva arising from sebaceous cell carcinoma. Despite the enthusiasm generated by the success of these agents, there are unanswered questions regarding the clinical efficacy of this new nonsurgical approach, and whether a single topical agent can achieve cure rates comparable with traditional therapies. Furthermore, the long-term consequences of prolonged courses of topical chemotherapeutic drugs on the ocular surface are unknown, and the ideal regimen for each of these agents is still being refined. In this review, we present specific guidelines for treating both melanocytic and squamous neoplasms of the conjunctiva, utilizing the available data in the literature as well as our own clinical experience at the Memorial Sloan-Kettering Cancer Center.Keywords: topical therapies, conjunctival neoplasms melanosis, Mitomycin-C, 5-Fluorouracil

  14. Natural gas annual 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-11-17

    The Natural Gas Annual provides information on the supply and disposition of natural gas to a wide audience including industry, consumers, Federal and State agencies, and educational institutions. The 1994 data are presented in a sequence that follows natural gas (including supplemental supplies) from its production to its end use. This is followed by tables summarizing natural gas supply and disposition from 1990 to 1994 for each Census Division and each State. Annual historical data are shown at the national level.

  15. Automated Word Puzzle Generation via Topic Dictionaries

    CERN Document Server

    Pinter, Balazs; Szabo, Zoltan; Lorincz, Andras

    2012-01-01

    We propose a general method for automated word puzzle generation. Contrary to previous approaches in this novel field, the presented method does not rely on highly structured datasets obtained with serious human annotation effort: it only needs an unstructured and unannotated corpus (i.e., document collection) as input. The method builds upon two additional pillars: (i) a topic model, which induces a topic dictionary from the input corpus (examples include e.g., latent semantic analysis, group-structured dictionaries or latent Dirichlet allocation), and (ii) a semantic similarity measure of word pairs. Our method can (i) generate automatically a large number of proper word puzzles of different types, including the odd one out, choose the related word and separate the topics puzzle. (ii) It can easily create domain-specific puzzles by replacing the corpus component. (iii) It is also capable of automatically generating puzzles with parameterizable levels of difficulty suitable for, e.g., beginners or intermedia...

  16. Risk assessment of topically applied products

    DEFF Research Database (Denmark)

    Søborg, Tue; Basse, Line Hollesen; Halling-Sørensen, Bent

    2007-01-01

    The human risk of harmful substances in semisolid topical dosage forms applied topically to normal skin and broken skin, respectively, was assessed. Bisphenol A diglycidyl ether (BADGE) and three derivatives of BADGE previously quantified in aqueous cream and the UV filters 3-BC and 4-MBC were used...... as model compounds. Tolerable daily intake (TDI) values have been established for BADGE and derivatives. Endocrine disruption was chosen as endpoint for 3-BC and 4-MBC. Skin permeation of the model compounds was investigated in vitro using pig skin membranes. Tape stripping was applied to simulate broken...... parameters for estimating the risk. The immediate human risk of BADGE and derivatives in topical dosage forms was found to be low. However, local treatment of broken skin may lead to higher exposure of BADGE and derivatives compared to application to normal skin. 3-BC permeated skin at higher flux than 4-MBC...

  17. Getting Started with Topic Modeling and MALLET

    Directory of Open Access Journals (Sweden)

    Shawn Graham

    2012-09-01

    Full Text Available In this lesson you will first learn what topic modeling is and why you might want to employ it in your research. You will then learn how to install and work with the MALLET natural language processing toolkit to do so. MALLET involves modifying an environment variable (essentially, setting up a short-cut so that your computer always knows where to find the MALLET program and working with the command line (ie, by typing in commands manually, rather than clicking on icons or menus. We will run the topic modeller on some example files, and look at the kinds of outputs that MALLET installed. This will give us a good idea of how it can be used on a corpus of texts to identify topics found in the documents without reading them individually.

  18. Lecture Notes on Topics in Accelerator Physics

    CERN Document Server

    Chao, A W

    2002-01-01

    These are lecture notes that cover a selection of topics, some of them under current research, in accelerator physics. I try to derive the results from first principles, although the students are assumed to have an introductory knowledge of the basics. The topics covered are: (1) Panofsky-Wenzel and Planar Wake Theorems; (2) Echo Effect; (3) Crystalline Beam; (4) Fast Ion Instability; (5) Lawson-Woodward Theorem and Laser Acceleration in Free Space; (6) Spin Dynamics and Siberian Snakes; (7) Symplectic Approximation of Maps; (8) Truncated Power Series Algebra; and (9) Lie Algebra Technique for nonlinear Dynamics. The purpose of these lectures is not to elaborate, but to prepare the students so that they can do their own research. Each topic can be read independently of the others.

  19. Topical and peripheral ketamine as an analgesic.

    Science.gov (United States)

    Sawynok, Jana

    2014-07-01

    Ketamine, in subanesthetic doses, produces systemic analgesia in chronic pain settings, an action largely attributed to block of N-methyl-D-aspartate receptors in the spinal cord and inhibition of central sensitization processes. N-methyl-D-aspartate receptors also are located peripherally on sensory afferent nerve endings, and this provided the initial impetus for exploring peripheral applications of ketamine. Ketamine also produces several other pharmacological actions (block of ion channels and receptors, modulation of transporters, anti-inflammatory effects), and while these may require higher concentrations, after topical (e.g., as gels, creams) and peripheral application (e.g., localized injections), local tissue concentrations are higher than those after systemic administration and can engage lower affinity mechanisms. Peripheral administration of ketamine by localized injection produced some alterations in sensory thresholds in experimental trials in volunteers and in complex regional pain syndrome subjects in experimental settings, but many variables were unaltered. There are several case reports of analgesia after topical application of ketamine given alone in neuropathic pain, but controlled trials have not confirmed such effects. A combination of topical ketamine with several other agents produced pain relief in case, and case series, reports with response rates of 40% to 75% in retrospective analyses. In controlled trials of neuropathic pain with topical ketamine combinations, there were improvements in some outcomes, but optimal dosing and drug combinations were not clear. Given orally (as a gargle, throat swab, localized peritonsillar injections), ketamine produced significant oral/throat analgesia in controlled trials in postoperative settings. Topical analgesics are likely more effective in particular conditions (patient factors, disease factors), and future trials of topical ketamine should include a consideration of factors that could predispose

  20. Topics in current aerosol research (part2)

    CERN Document Server

    Hidy, G M

    1972-01-01

    Topics in Current Aerosol Research, Part 2 contains some selected articles in the field of aerosol study. The chosen topics deal extensively with the theory of diffusiophoresis and thermophoresis. Also covered in the book is the mathematical treatment of integrodifferential equations originating from the theory of aerosol coagulation. The book is the third volume of the series entitled International Reviews in Aerosol Physics and Chemistry. The text offers significant understanding of the methods employed to develop a theory for thermophoretic and diffusiophoretic forces acting on spheres in t

  1. Illustrative EDOF topics in Fourier optics

    Science.gov (United States)

    George, Nicholas; Chen, Xi; Chi, Wanli

    2011-10-01

    In this talk we present a series of illustrative topics in Fourier Optics that are proving valuable in the design of EDOF camera systems. They are at the level of final examination problems that have been made solvable by a student or professoi having studied from one of Joseph W. Goodman's books---our tribute for his 75fr year. As time permits, four illustrative topics are l) Electromagnetic waves and Fourier optics;2) The perfect lens; 3) Connection between phase delay and radially varying focal length in an asphere and 4) tailored EDOF designs.

  2. Topical therapy in atopic dermatitis in children

    Directory of Open Access Journals (Sweden)

    Dharshini Sathishkumar

    2016-01-01

    Full Text Available Atopic dermatitis (AD is a common, chronic childhood skin disorder caused by complex genetic, immunological, and environmental interactions. It significantly impairs quality of life for both child and family. Treatment is complex and must be tailored to the individual taking into account personal, social, and emotional factors, as well as disease severity. This review covers the management of AD in children with topical treatments, focusing on: education and empowerment of patients and caregivers, avoidance of trigger factors, repair and maintenance of the skin barrier by correct use of emollients, control of inflammation with topical corticosteroids and calcineurin inhibitors, minimizing infection, and the use of bandages and body suits.

  3. Topic Time Series Analysis of Microblogs

    Science.gov (United States)

    2014-10-01

    does not display a currently valid OMB control number. 1. REPORT DATE OCT 2014 2. REPORT TYPE 3. DATES COVERED 00-00-2014 to 00-00-2014 4. TITLE...Tweets in topic k triggered by a Tweet in topic k, also known as the branching factor. ωk is a parameter controlling the rate of decay, i.e. how...2011. [20] Yosihiko Ogata . Statistical models for earthquake occurrences and residual analysis for point pro- cesses. Journal of the American

  4. Safety of topical vancomycin powder in neurosurgery

    Directory of Open Access Journals (Sweden)

    Kalil G Abdullah

    2016-01-01

    Full Text Available Surgical site infections (SSIs remain an important cause of morbidity following neurosurgical procedures despite the best medical practices. In addition, hospital infection rates are proposed as a metric for ranking hospitals safety profiles to guide medical consumerism. Recently, the use of topical vancomycin, defined as the application of vancomycin powder directly into the surgical wound, has been described in both cranial and spinal surgeries as a method to reduce SSIs. Early results are promising. Here, we provide a concise primer on the pharmacology, bacterial spectrum, history, and clinical indications of topical vancomycin for the practicing surgeon.

  5. Applied atomic and collision physics special topics

    CERN Document Server

    Massey, H S W; Bederson, Benjamin

    1982-01-01

    Applied Atomic Collision Physics, Volume 5: Special Topics deals with topics on applications of atomic collisions that were not covered in the first four volumes of the treatise. The book opens with a chapter on ultrasensitive chemical detectors. This is followed by separate chapters on lighting, magnetohydrodynamic electrical power generation, gas breakdown and high voltage insulating gases, thermionic energy converters, and charged particle detectors. Subsequent chapters deal with the operation of multiwire drift and proportional chambers and streamer chambers and their use in high energy p

  6. Heart block following topical latanoprost treatment

    Science.gov (United States)

    De Smit, Elisabeth; Theodorou, Maria; Hildebrand, Göran Darius; Bloom, Philip

    2011-01-01

    The authors report a case of second degree heart block associated with topical latanoprost treatment. The authors discuss the possibility of a causative effect as the cessation of this treatment resulted in improvement of the arrhythmia. The authors highlight previous reports and research in humans and animals which demonstrate an association of arrhythmias with prostaglandin analogues. This report draws attention to the possibility that an extremely commonly prescribed topical drug may trigger arrhythmias in susceptible individuals. It is important that prescribers are aware of this possible side-effect. PMID:22679164

  7. IEA-Advanced Motor Fuels Annual Report 2012

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-06-15

    The annual report from the IEA implementing agreement on Advanced Motor Fuels (AMF) describes what the agreement is about, how to join, various activities of the agreement, a message from the Chairman, and projects/annexes active for the year. An annual section covers the global situation for the topic of advanced motor fuels. Another section includes highlights coming from each country participating in AMF, and major sections relaying activities on each of the ongoing annexes. Information regarding participating delegations, contact information, publications resulting from AMF, and upcoming meetings rounds out the report.

  8. IEA-Advanced Motor Fuels Annual Report 2011

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    The annual report from the IEA implementing agreement on Advanced Motor Fuels (AMF) describes what the agreement is about, how to join, various activities of the agreement, a message from the Chairman, and projects/annexes active for the year. An annual section covers the global situation for the topic of advanced motor fuels. Another section includes highlights coming from each country participating in AMF, and major sections relaying activities on each of the ongoing annexes. Information regarding participating delegations, contact information, publications resulting from AMF, and upcoming meetings rounds out the report.

  9. 9th Annual UNCG Regional Mathematics and Statistics Conference

    CERN Document Server

    Chhetri, Maya; Gupta, Sat; Shivaji, Ratnasingham

    2015-01-01

    This volume contains rigorously reviewed papers on the topics presented by students at The 9th Annual University of North Carolina at Greensboro Regional Mathematics and Statistics Conference (UNCG RMSC) that took place on November 2, 2013.  All papers are coauthored by student researchers and their faculty mentors. This conference series was inaugurated in 2005, and it now attracts over 150 participants from over 30 universities from North Carolina and surrounding states. The conference is specifically tailored for students to present their research projects that encompass a broad spectrum of topics in mathematics, mathematical biology, statistics, and computer science.

  10. 75 FR 26647 - Ophthalmic and Topical Dosage Form New Animal Drugs; Ivermectin Topical Solution

    Science.gov (United States)

    2010-05-12

    ... HUMAN SERVICES Food and Drug Administration 21 CFR Part 524 Ophthalmic and Topical Dosage Form New Animal Drugs; Ivermectin Topical Solution AGENCY: Food and Drug Administration, HHS. ACTION: Final rule, technical amendment. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug...

  11. 76 FR 81806 - Ophthalmic and Topical Dosage Form New Animal Drugs; Ivermectin Topical Solution

    Science.gov (United States)

    2011-12-29

    ... HUMAN SERVICES Food and Drug Administration 21 CFR Part 524 Ophthalmic and Topical Dosage Form New Animal Drugs; Ivermectin Topical Solution AGENCY: Food and Drug Administration, HHS. ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations to...

  12. Are one or two dangerous? Lidocaine and topical anesthetic exposures in children.

    Science.gov (United States)

    Curtis, Liesl A; Dolan, Teresa Sullivan; Seibert, H Edward

    2009-07-01

    Topical anesthetics are found in a variety of prescription and non-prescription preparations, from teething gels to hemorrhoid creams. In 2003, there were 8576 exposures to local/topical anesthetics reported to the American Association of Poison Control Centers, with 67% of cases in the age group younger than 6 years old. This report reviews the available literature involving topical anesthetic exposures in children younger than 6 years old, including the National Library of Medicine's Pub Med database (limited to English language) and data from POISINDEX. Additionally, we reviewed the American Association of Poison Control Centers' annual reports from 1983 to 2003. There were 7 deaths in this age range from topical anesthetics. Although the number of deaths is low, the fact that there have been deaths reveals the serious nature of the toxicity that can result from these readily available non-prescription analgesics. Toxicity may result from topical absorption, ingestion, or aspiration. Additionally, toxicity can result from unintentional as well as therapeutic mishaps. Although the number of cases is limited, these medications can be toxic at low doses-which, in children younger than 6 years of age, may amount to as little as a teaspoon.

  13. Novel Topic Impact on Authorship Attribution

    Science.gov (United States)

    2009-12-01

    consisted of 72 documents written by eight students . Each student wrote a total of 24 documents in three different genres about three different topics [14...attribution," in Proceedings of the SIGIR 󈧋 Workshop on Plagiarism Analysis, Authorship Identification, and Near-Duplicate Detection, PAN 2007

  14. Special topics in the theory of piezoelectricity

    CERN Document Server

    Yang, Jiashi

    2009-01-01

    Piezoelectricity has been a steadily growing field, with recent advances made by researchers from applied physics, acoustics, materials science, and engineering. This collective work presents a comprehensive treatment of selected advanced topics in the subject. The book is written for an intermediate graduate level and is intended for researchers, mechanical engineers, and applied mathematicians interested in the advances and new applications in piezoelectricity.

  15. An Emerging Era in Topical Delivery: Organogels

    Directory of Open Access Journals (Sweden)

    Sreedevi.T

    2012-06-01

    Full Text Available Semisolid preparations for external application to skin have gained much demand, since it is easily absorbed through the skin layers. Many novel topical dosage forms have been discovered, among which organogels appears to play an important role. Organogels are thermodynamically stable, biocompatible, isotropic gel, which not only give localised effect, but also systemic effect through percutaneous absorption. Although different types of gelator molecules are being used for the development of organogels, both egg and soya lecithin are mainly focused. The purity of lecithin is also considered to be an important factor in gelation. Apart from lecithin, non-ionic surfactant based microemulsion gels and pluronic organogels are also being developed. Compared to conventional topical dosage forms, these novel formulations are found to be more advantageous and efficient. In future, organogels can give way to many promising discoveries in the field of topical dosage forms. The current review aims at giving an idea about organogels, its applications and importance in topical delivery.

  16. Seven topics in functional magnetic resonance imaging.

    Science.gov (United States)

    Bandettini, Peter A

    2009-09-01

    Functional MRI (fMRI) is a non-invasive brain imaging methodology that started in 1991 and allows human brain activation to be imaged at high resolution within only a few minutes. Because it has extremely high sensitivity, is relatively easy to implement, and can be performed on most standard clinical MRI scanners. It continues to grow at an explosive rate throughout the world. Over the years, at any given time, fMRI has been defined by only a handful of major topics that have been the focus of researchers using and developing the methodology. In this review, I attempt to take a snapshot of the field of fMRI as it is in mid-2009 by discussing the seven topics that I feel are most on the minds of fMRI researchers. The topics are, in no particular order or grouping: (1) Clinical impact, (2) Utilization of individual functional maps, (3) fMRI signal interpretation, (4) Pattern effect mapping and decoding, (5) Endogenous oscillations, (6) MRI technology, and (7) Alternative functional contrast mechanisms. Most of these topics are highly interdependent, each advancing as the others advance. While most fMRI involves applications towards clinical or neuroscience questions, all applications are fundamentally dependent on advances in basic methodology as well as advances in our understanding of the relationship between neuronal activity and fMRI signal changes. This review neglects almost completely an in-depth discussion of applications. Rather the discussions are on the methods and interpretation.

  17. Six Hot Topics in Planetary Astronomy

    OpenAIRE

    Jewitt, David

    2008-01-01

    Six hot topics in modern planetary astronomy are described: 1) lightcurves and densities of small bodies 2) colors of Kuiper belt objects and the distribution of the ultrared matter 3) spectroscopy and the crystallinity of ice in the outer Solar system 4) irregular satellites of the giant planets 5) the Main Belt Comets and 6) comets and meteor stream parents.

  18. Expose Mechanical Engineering Students to Biomechanics Topics

    Science.gov (United States)

    Shen, Hui

    2011-01-01

    To adapt the focus of engineering education to emerging new industries and technologies nationwide and in the local area, a biomechanics module has been developed and incorporated into a mechanical engineering technical elective course to expose mechanical engineering students at ONU (Ohio Northern University) to the biomedical engineering topics.…

  19. Contact Dermatitis From Topical Application Of Mercurochrome

    Directory of Open Access Journals (Sweden)

    Saha Sib Shankar

    1995-01-01

    Full Text Available Mercury in its metallic from and its other salts may cause contact dermatitis and eczema; but contact allergy due to them is rather uncommon. A case of eczematous reaction due to topical application of mercurochrome developing within one day is being reported.

  20. Contact Dermatitis From Topical Application Of Mercurochrome

    OpenAIRE

    Saha Sib Shankar; Manjumdar Sabyasachi

    1995-01-01

    Mercury in its metallic from and its other salts may cause contact dermatitis and eczema; but contact allergy due to them is rather uncommon. A case of eczematous reaction due to topical application of mercurochrome developing within one day is being reported.

  1. Topical morphine for oral mucositis in children

    DEFF Research Database (Denmark)

    Nielsen, Bettina Nygaard; Aagaard, Gitte; Henneberg, Steen W;

    2012-01-01

    Systemic opioids for painful chemotherapy-induced oral mucositis in children often result in unsatisfactory pain relief and a high frequency of side effects. Opioids applied topically can produce analgesia by binding to opioid receptors on peripheral terminals of sensory neurons. These receptors...

  2. Topical beta-Blockers and Mortality

    NARCIS (Netherlands)

    Muskens, Rogier P. H. M.; Wolfs, Roger C. W.; Wittenian, Jacqueline C. M.; Hofman, Albert; de Jong, Paulus T. V. M.; Stricker, Bruno H. C.; Jansonius, Nomdo M.

    2008-01-01

    Purpose: To study the associations between long-term and short-term use of topical beta-blockers and mortality. Design: Prospective population-based cohort study. Participants: To examine long-term effects, 3842 participants aged 55 years and older were recruited. To examine short-term effects, 484

  3. Teaching Difficult Topics with Primary Sources

    Science.gov (United States)

    Potter, Lee Ann

    2011-01-01

    "Difficult" or "challenging" topics to teach include racism, violence, genocide, bullying, gangs, abuse (physical, emotional, and substance), slavery, suffering, hatred, terrorism, war, disease, loss, addiction, and more. But by confronting them with students, in the safety of a classroom through thoughtfully constructed lessons (ones that take…

  4. Mobility Aids: MedlinePlus Health Topic

    Science.gov (United States)

    ... ClinicalTrials.gov: Self-Help Devices (National Institutes of Health) Journal Articles References and abstracts from MEDLINE/PubMed (National ... Eldercare at Home: Mobility Problems (AGS Foundation for Health in Aging) Topic Image MedlinePlus Email Updates Get Mobility Aids ...

  5. Deep Belief Nets for Topic Modeling

    DEFF Research Database (Denmark)

    Maaløe, Lars; Arngren, Morten; Winther, Ole

    2015-01-01

    . Efficient retrieval can be carried out in the latent representation. We work both on public benchmarks and digital media content provided by Issuu, an on-line publishing platform. This article also comes with a newly developed deep belief nets toolbox for topic modeling tailored towards performance...

  6. Common Core: Teaching Optimum Topic Exploration (TOTE)

    Science.gov (United States)

    Karge, Belinda Dunnick; Moore, Roxane Kushner

    2015-01-01

    The Common Core has become a household term and yet many educators do not understand what it means. This article explains the historical perspectives of the Common Core and gives guidance to teachers in application of Teaching Optimum Topic Exploration (TOTE) necessary for full implementation of the Common Core State Standards. An effective…

  7. Tracking Multiple Topics for Finding Interesting Articles

    Energy Technology Data Exchange (ETDEWEB)

    Pon, R K; Cardenas, A F; Buttler, D J; Critchlow, T J

    2007-02-15

    We introduce multiple topic tracking (MTT) for iScore to better recommend news articles for users with multiple interests and to address changes in user interests over time. As an extension of the basic Rocchio algorithm, traditional topic detection and tracking, and single-pass clustering, MTT maintains multiple interest profiles to identify interesting articles for a specific user given user-feedback. Focusing on only interesting topics enables iScore to discard useless profiles to address changes in user interests and to achieve a balance between resource consumption and classification accuracy. Also by relating a topic's interestingness to an article's interestingness, iScore is able to achieve higher quality results than traditional methods such as the Rocchio algorithm. We identify several operating parameters that work well for MTT. Using the same parameters, we show that MTT alone yields high quality results for recommending interesting articles from several corpora. The inclusion of MTT improves iScore's performance by 9% to 14% in recommending news articles from the Yahoo! News RSS feeds and the TREC11 adaptive filter article collection. And through a small user study, we show that iScore can still perform well when only provided with little user feedback.

  8. Water: A Topic for All Sciences

    Science.gov (United States)

    Davies, Malonne I.; Seimears, C. Matt

    2008-01-01

    The authors illustrate an effective lesson-planning technique known as unpacking for the broad topic of water. Interconnections among science disciplines are shown for numerous possible subtopics. Two lesson sets are included, the first dealing with properties of water and the second dealing with water as a resource. (Contains 1 table and 4…

  9. Proceedings of the 37. annual colloquium and annual general meeting 2011

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    The 37th annual colloquium and annual general meeting 2011 of the Atlantic Geoscience Society was held in Fredericton, New Brunswick, Canada, from February 11th to February 12th, 2011. This colloquium brought together members of the Atlantic Geoscience Society to discuss hot topics in the geoscience sector in Atlantic Canada. The colloquium provided the participants with the opportunity to listen to presentations on subjects such as new developments in the Appalachian Orogen, groundwater vulnerability in Atlantic Canada with climate change, sea water intrusion, agriculture and other stressors, and new developments in Atlantic geoscience. And it was a favourable occasion for participants to network with peers and share expertise. 3 out of the 9 papers presented during this conference have been catalogued separately for inclusion in this database.

  10. Proceedings from the 5th Annual International Society for Musculoskeletal Imaging in Rheumatology Annual Conference.

    Science.gov (United States)

    Conaghan, Philip G; Ostergaard, Mikkel; D'Agostino, Maria Antonietta; Gaylis, Norman; Arnold, William; Olech, Ewa; Wells, Alvin; Peterfy, Charles; Seraphine, Judy L; Troum, Orrin

    2013-02-01

    Since its inception, ISEMIR has held an annual education meeting highlighting the changes in the utilization of imaging tools for the management of rheumatic diseases. ISEMIR's international faculty and world-renowned experts have discussed these topics at a very high scientific level. The evolution of the content demonstrates the rapidly changing environment in the field of rheumatology. Advances in treatment have led to the increased use of magnetic resonance imaging (MRI) and ultrasound (US). This publication is based upon the proceedings from the 2012 ISEMIR educational meeting that took place on April 26th in Chicago, Illinois. Presentations from the live proceedings can be viewed at www.isemir.org.

  11. Assessing adherence factors in patients under topical treatment: development of the Topical Therapy Adherence Questionnaire (TTAQ).

    Science.gov (United States)

    Zschocke, Ina; Mrowietz, Ulrich; Lotzin, Annett; Karakasili, Eleni; Reich, Kristian

    2014-04-01

    Medication adherence rates strongly depend on favorable disease outcomes. It is known that medication adherence rates are lower for topical treatment than for systemic treatment. However, to date no validated instrument for the assessment of adherence factors in topical treatment is available. The aim of this study was to develop a new questionnaire to assess adherence risk factors in topical treatment. The development of the Topical Therapy Adherence Questionnaire (TTAQ) and Patient Preference Questionnaire (PPQ) was based on a systematic literature review, and qualitative patient focus interviews and expert focus groups' input. The psychometric properties and comprehensibility of the TTAQ and PPQ were assessed in a feasibility study with 59 psoriasis patients. Our first preliminary results indicate that the TTAQ and PPQ are psychometrically sound and reliable measures for the assessment of factors influencing topical treatment adherence. The questionnaires are currently being further developed and various parameters (e.g., time point of assessment) are currently being tested in an exploratory pilot study with ca. 2,000 psoriasis patients receiving topical treatment in a European clinical trial. The use of the final versions of TTAQ and PPQ in clinical practice may facilitate the early identification of specific non-adherence factors in patients under topical treatment, which could enable designing and applying adherence-enhancing interventions according to the patient's individual needs.

  12. Natural gas annual 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-10-01

    The Natural Gas Annual provides information on the supply and disposition of natural gas to a wide audience including industry, consumers, Federal and State agencies, and educational institutions. The 1997 data are presented in a sequence that follows natural gas (including supplemental supplies) from its production to its end use. This is followed by tables summarizing natural gas supply and disposition from 1993 to 1997 for each Census Division and each State. Annual historical data are shown at the national level. 27 figs., 109 tabs.

  13. International energy annual 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-02-01

    The International Energy Annual presents an overview of key international energy trends for production, consumption, imports, and exports of primary energy commodities in over 220 countries, dependencies, and areas of special sovereignty. Also included are population and gross domestic product data, as well as prices for crude oil and petroleum products in selected countries. Renewable energy reported in the International Energy Annual includes hydroelectric power, geothermal, solar, and wind electric power, biofuels energy for the US, and biofuels electric power for Brazil. New in the 1996 edition are estimates of carbon dioxide emissions from the consumption of petroleum and coal, and the consumption and flaring of natural gas. 72 tabs.

  14. Main technical topics in 1999; Les elements marquants de 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This Safety Authority annual report strives to present current organizational provisions and future trends in nuclear safety supervision in France and to describe the most outstanding occurrences during the past year. A first part presents nine documents concerning the main topics of 1999: aging of nuclear installations, the Offsite Emergency Plans (PPI), the impact of nuclear activities on man and the environment, the criticality hazards, EDF in 1999, the EPR project, the Andra in 1999, the transport incidents, the nuclear safety in eastern Europe. The second part presents the missions and actions of the Nuclear Installations Safety in the domains of the liabilities, the organization of the nuclear safety control, the regulations of the INB, the public information, the international relations, the crisis management, the radioactive materials transportation, the radioactive wastes. The equipment, the radiation protection and the exploitation of the pressurized water reactors are also treated just as the experimental reactors, the fuel cycle installations and the the nuclear installations dismantling. (A.L.B.)

  15. Optical fibers and photonics applications: topical tracks at Wilga conferences

    Science.gov (United States)

    Romaniuk, Ryszard S.

    2013-01-01

    This paper is a research survey of WILGA Symposium work, 2010-2012 Editions, concerned with Optical Fibers, Optoelectronic Devices, Sensors, Communication and Photonics Applications. It presents a digest of chosen technical work results shown by young researchers from different technical universities from this country during the three recent Wilga Symposia on Photonics and Web Engineering. Topical tracks of the symposia embraced, among others, nanomaterials and nanotechnologies for photonics, sensory and nonlinear optical fibers, object oriented design of hardware, photonic metrology, optoelectronics and photonics applications, photonics-electronics co-design, optoelectronic and electronic systems for astronomy and high energy physics experiments, photonic equipment for JET tokamak and pi-of-the sky experiments development. The symposium is an annual summary in the development of numerable Ph.D. theses carried out in this country in the area of advanced electronic and photonic systems. It is also a great occasion for SPIE, IEEE, OSA and PSP students to meet together in a large group spanning the whole country with guests from this part of Europe. A digest of Wilga references is presented [1-274]. Wilga Symposia play a role of an universal integrator of young science in photonics and related areas in this country and also in this part of Europe. More than 5000 young scientists participated in scientific Wilga meetings and discussions during the last nearly two decades. Over 2500 papers were published, including over 1000 in Proc. SPIE.

  16. Topics in modern physics theoretical foundations

    CERN Document Server

    Walecka, John Dirk

    2013-01-01

    While the two previous books entitled Introduction to Modern Physics: Theoretical Foundations and Advanced Modern Physics: Theoretical Foundations exposed the reader to the foundations and frontiers of today's physics, the goal of this third volume is to cover in some detail several topics omitted in the essentially linear progression of the first two. This book is divided into three parts. Part 1 is on quantum mechanics. Analytic solutions to the Schrödinger equation are developed for some basic systems. The analysis is then formalized, concluding with a set of postulates for the theory. Part 2 is on applications of quantum mechanics: approximation methods for bound states, scattering theory, time-dependent perturbation theory, and electromagnetic radiation and quantum electrodynamics. Part 3 covers some selected topics in relativistic quantum field theory: discrete symmetries, the Heisenberg picture, and the Feynman rules for quantum chromodynamics. The three volumes in this series taken together provide ...

  17. [Update of the topical treatment of psoriasis].

    Science.gov (United States)

    Carrascosa, J M; Vanaclocha, F; Borrego, L; Fernández-López, E; Fuertes, A; Rodríguez-Fernández-Freire, L; Zulaica, A; Tuneu, A; Caballé, G; Colomé, E; Bordas, X; Hernanz, J M; Brufau, C; Herrera, E

    2009-04-01

    Topical therapy continues to be one of the pillars of psoriasis management. Topical corticosteroids and vitamin D analogs are the drugs of choice during the induction phase, and vitamin D analogs continue to be drugs of choice for maintenance therapy. Tazarotene and dithranol are suitable options in patients with certain, specific characteristics. The calcineurin inhibitors can be considered to be second-line treatment for psoriasis of the face and flexures. The efficacy and safety of the fixed-dose combination of betamethasone and calcipotriol in the induction phase is greater than that of either drug alone. The combination of corticosteroids with salicylic acid achieves better results than corticosteroids in monotherapy. None of the drugs evaluated stands out over the others in all clinical situations, and their use must therefore be individualized in each patient and adjusted according to the course of the disease.

  18. Topics from the theory of numbers

    CERN Document Server

    Grosswald, Emil

    1984-01-01

    Many of the important and creative developments in modern mathematics resulted from attempts to solve questions that originate in number theory. The publication of Emil Grosswald’s classic text presents an illuminating introduction to number theory. Combining the historical developments with the analytical approach, Topics from the Theory of Numbers offers the reader a diverse range of subjects to investigate, including: * divisibility * congruences * the Riemann zeta function * Diophantine equations and Fermat’s conjecture * the theory of partitions Comprehensive in nature, Topics from the Theory of Numbers is an ideal text for advanced undergraduates and graduate students alike. "In my opinion it is excellent. It is carefully written and represents clearly a work of a scholar who loves and understands his subject. One can only wish more authors would take such pains and would be as good and honest expositors as Grosswald." — Marc Kac "This book is designed for use in a first course in number theory at...

  19. Modern topics in theoretical nuclear physics

    OpenAIRE

    Jennings, B. K.; Schwenk, A.

    2005-01-01

    Over the past five years there have been profound advances in nuclear physics based on effective field theory and the renormalization group. In this brief, we summarize these advances and discuss how they impact our understanding of nuclear systems and experiments that seek to unravel their unknowns. We discuss future opportunities and focus on modern topics in low-energy nuclear physics, with special attention to the strong connections to many-body atomic and condensed matter physics, as wel...

  20. Topical Day on Biological Effects of Radiation

    Energy Technology Data Exchange (ETDEWEB)

    Baatout, S.; Jacquet, P.

    1997-05-15

    The topical day has been focussed on the potential effects of ionizing radiation on human health. A general overview on molecular and biophysical aspects of radiation, its effects on cells and organisms, and the contribution of radiobiology to radiation protection and risk assessment is given. The genetic effects of radiation and its effects on the developing organism, the effects of radiation on the cell cycle and the mechanisms of radiation induced apoptosis were also discussed.

  1. Topics on tournaments in graph theory

    CERN Document Server

    Moon, John W

    2015-01-01

    Tournaments, in this context, are directed graphs ― an important and interesting topic in graph theory. This concise volume collects a substantial amount of information on tournaments from throughout the mathematical literature. Suitable for advanced undergraduate students of mathematics, the straightforward treatment requires a basic familiarity with finite mathematics. The fundamental definitions and results appear in the earlier sections, and most of the later sections can be read independently of each other. Subjects include irreducible and strong tournaments, cycles and strong subtourname

  2. Contraception via topical application? - A review.

    Science.gov (United States)

    Schaefer, H; Stüttgen, G; Schalla, W

    1979-09-01

    The skin, generally speaking, is not an absorption organ but one of its major functions is the protection of the body against the entrance of foreign material. Under certain circumstances, however, drugs can be introduced into the skin and thereby into the body as can be seen in the topical treatment of skin diseases. Though percutaneous pharmacokinetics of steroids seem appropriate for contraception, the variability of the absorption process appears to be too high for this purpose.

  3. Psoriasis and psoriatic arthritis: Topical issues

    Directory of Open Access Journals (Sweden)

    Yulia Leonidovna Korsakova

    2012-09-01

    Full Text Available The topical issues of the diagnosis and treatment of psoriasis (Ps and psoriatic arthritis (PsA are discussed. The characteristics and treatments of Ps and the methods for the diagnosis of PsA in Ps are presented; the extraarticular manifestations of PsA, its radiological signs, criteria for a treatment response, the current principles of therapy, and prognosis in these patients are described.

  4. Topics in theoretical and applied statistics

    CERN Document Server

    Giommi, Andrea

    2016-01-01

    This book highlights the latest research findings from the 46th International Meeting of the Italian Statistical Society (SIS) in Rome, during which both methodological and applied statistical research was discussed. This selection of fully peer-reviewed papers, originally presented at the meeting, addresses a broad range of topics, including the theory of statistical inference; data mining and multivariate statistical analysis; survey methodologies; analysis of social, demographic and health data; and economic statistics and econometrics.

  5. Forewords Special Topic Issue on Nanophotonics

    Institute of Scientific and Technical Information of China (English)

    Yiping Cui; Joseph W.Haus

    2009-01-01

    @@ This Special Topic Issue has grown out of research that has been highlighted at the Nanophotonics Conference series held in China for the past three years.The fourteen papers appearing in this issue are a small sampling of the total scope of the conference.Broadly speaking,the subjects covered by the contributing authors include quantum properties using semiconductor materials,nanocharacterization especially with applications to medical fields,photonic crystals and fibers,and plasmonics.

  6. Annual report 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-10-01

    The annual report from IKU (Continental Shelf Institute) in Norway deals with the market adjustment of research activities at the institute as a result of offshore cost-cutting policy in the petroleum industry. The market is about to shift focus from volume to competence. In practice, that means buying competence instead of project ideas or proposals

  7. Carolinas Communication Annual, 1998.

    Science.gov (United States)

    McLennan, David B.

    1998-01-01

    This 1998 issue of "Carolinas Communication Annual" contains the following articles: "Give Me That Old Time Religion?: A Study of Religious Themes in the Rhetoric of the Ku Klux Klan" (John S. Seiter); "The Three Stooges versus the Third Reich" (Roy Schwartzman); "Interdisciplinary Team Teaching: Implementing…

  8. Annual report 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-09-01

    SaskPower`s mission is to meet the electrical needs of Saskatchewan residents in a reliable, safe, efficient and environmentally responsible manner. This annual report of the Corporation discusses new business focus; operations highlights; quality of life; management discussion and analysis; financial ratios; and a report of management. Financial information is also included.

  9. Annual Report 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    The Institut Laue-Langevin (ILL) is an international research center using neutrons to probe the microscopic structure and dynamics of a broad range of materials. This annual report presents the ILL activities in 2000: the scientific highlights, the Millennium programme and the new developments, the workshops organized by the ILL, the experimental programme and the publications. (A.L.B.)

  10. 2010 AAUW Annual Report

    Science.gov (United States)

    American Association of University Women, 2010

    2010-01-01

    This report highlights some of the outstanding accomplishments of AAUW (American Association of University Women) for fiscal year 2010. This year's annual report also features stories of remarkable women who are leading the charge to break through barriers and ensure that all women have a fair chance. Sharon is working to reduce the pay gap…

  11. NERSC Annual Report 2004

    Energy Technology Data Exchange (ETDEWEB)

    Hules, John; Bashor, Jon; Yarris, Lynn; McCullough, Julie; Preuss, Paul; Bethel, Wes

    2005-04-15

    The National Energy Research Scientific Computing Center (NERSC) is the premier computational resource for scientific research funded by the DOE Office of Science. The Annual Report includes summaries of recent significant and representative computational science projects conducted on NERSC systems as well as information about NERSC's current and planned systems and services.

  12. International Energy Annual, 1992

    Energy Technology Data Exchange (ETDEWEB)

    1994-01-14

    This report is prepared annually and presents the latest information and trends on world energy production and consumption for petroleum, natural gas, coal, and electricity. Trade and reserves are shown for petroleum, natural gas, and coal. Prices are included for selected petroleum products. Production and consumption data are reported in standard units as well as British thermal units (Btu) and joules.

  13. UNICEF Annual Report. 1984.

    Science.gov (United States)

    United Nations Children's Fund, New York, NY.

    This annual report reviews the work UNICEF has been doing to help transform the "Child Survival Revolution" from a dream into a reality. Discussion focuses primarily on child health and nutrition and other basic services for children. Throughout, the review is supplemented with profiles of program initiatives made to improve the…

  14. Mail Office annual closure

    CERN Multimedia

    2013-01-01

    On the occasion of the annual closure of CERN, there will be no mail distributed on Friday 20 December 2013 but mail will be collected in the morning. Nevertheless, you will still be able to bring your outgoing mail to Building 555-R-002 until 12 noon.  

  15. Annual HR Salary Survey.

    Science.gov (United States)

    Schaeffer, Patricia

    2000-01-01

    A trainers' salary survey collected data on 1,091 companies, 31,615 employees, and 97 human resource jobs. Results show pay for human resource professionals is continuing to rise. The survey contains information on base salaries, annual bonuses and incentives, and long-term eligibility incentives. (JOW)

  16. NRCC annual report, 1979

    Energy Technology Data Exchange (ETDEWEB)

    1980-11-01

    This annual report of the National Research for Computation in Chemistry (NRCC) Division describes the program of research workshops, software development, and scientific research of the Division in 1979. This year marked the first full calendar year of activity of the Division. Initial staffing in the core scientific areas was completed by the addition of a crystallographer.

  17. NERSC Annual Report 2002

    Energy Technology Data Exchange (ETDEWEB)

    Hules, John

    2003-01-31

    The National Energy Research Scientific Computing Center (NERSC) is the primary computational resource for scientific research funded by the DOE Office of Science. The Annual Report for FY2002 includes a summary of recent computational science conducted on NERSC systems (with abstracts of significant and representative projects), and information about NERSC's current and planned systems and service

  18. NERSC Annual Report 2005

    Energy Technology Data Exchange (ETDEWEB)

    Hules (Ed.), John

    2006-07-31

    The National Energy Research Scientific Computing Center (NERSC) is the premier computational resource for scientific research funded by the DOE Office of Science. The Annual Report includes summaries of recent significant and representative computational science projects conducted on NERSC systems as well as information about NERSC's current and planned systems and services.

  19. Uranium industry annual 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-04-22

    The Uranium Industry Annual 1998 (UIA 1998) provides current statistical data on the US uranium industry`s activities relating to uranium raw materials and uranium marketing. It contains data for the period 1989 through 2008 as collected on the Form EIA-858, ``Uranium Industry Annual Survey.`` Data provides a comprehensive statistical characterization of the industry`s activities for the survey year and also include some information about industry`s plans and commitments for the near-term future. Data on uranium raw materials activities for 1989 through 1998, including exploration activities and expenditures, EIA-estimated reserves, mine production of uranium, production of uranium concentrate, and industry employment, are presented in Chapter 1. Data on uranium marketing activities for 1994 through 2008, including purchases of uranium and enrichment services, enrichment feed deliveries, uranium fuel assemblies, filled and unfilled market requirements, and uranium inventories, are shown in Chapter 2. The methodology used in the 1998 survey, including data edit and analysis, is described in Appendix A. The methodologies for estimation of resources and reserves are described in Appendix B. A list of respondents to the ``Uranium Industry Annual Survey`` is provided in Appendix C. The Form EIA-858 ``Uranium Industry Annual Survey`` is shown in Appendix D. For the readers convenience, metric versions of selected tables from Chapters 1 and 2 are presented in Appendix E along with the standard conversion factors used. A glossary of technical terms is at the end of the report. 24 figs., 56 tabs.

  20. 2011 NASA Range Safety Annual Report

    Science.gov (United States)

    Dumont, Alan G.

    2012-01-01

    Welcome to the 2011 edition of the NASA Range Safety Annual Report. Funded by NASA Headquarters, this report provides a NASA Range Safety overview for current and potential range users. As is typical with odd year editions, this is an abbreviated Range Safety Annual Report providing updates and links to full articles from the previous year's report. It also provides more complete articles covering new subject areas, summaries of various NASA Range Safety Program activities conducted during the past year, and information on several projects that may have a profound impact on the way business will be done in the future. Specific topics discussed and updated in the 2011 NASA Range Safety Annual Report include a program overview and 2011 highlights; Range Safety Training; Range Safety Policy revision; Independent Assessments; Support to Program Operations at all ranges conducting NASA launch/flight operations; a continuing overview of emerging range safety-related technologies; and status reports from all of the NASA Centers that have Range Safety responsibilities. Every effort has been made to include the most current information available. We recommend this report be used only for guidance and that the validity and accuracy of all articles be verified for updates. Once again the web-based format was used to present the annual report. We continually receive positive feedback on the web-based edition and hope you enjoy this year's product as well. As is the case each year, contributors to this report are too numerous to mention, but we thank individuals from the NASA Centers, the Department of Defense, and civilian organizations for their contributions. In conclusion, it has been a busy and productive year. I'd like to extend a personal Thank You to everyone who contributed to make this year a successful one, and I look forward to working with all of you in the upcoming year.

  1. Application of Topic Map on Knowledge Organization

    Directory of Open Access Journals (Sweden)

    Sou-shan Wu

    2003-06-01

    Full Text Available Knowledge management (KM has received much attention from both academics and practitioners in the past few years. Following the KM trend, many organizations have built their own knowledge repositories or data warehouses. However, information or knowledge is still scattered everywhere without being properly managed. The rapid growth of the Internet accelerates the creation of unstructured and unclassified information and causes the explosion of information overload. The effort of browsing information through general-purpose search engines turns out to be tedious and painstaking. Hence, an effective technology to solve this information retrieval problem is much needed. The purpose of this research is to explore the application of text mining technique in organizing knowledge stored in unstructured natural language text documents. Major components of text mining techniques required for topic map in particular will be presented in detail.Two sets of unstructured documents are utilized to demonstrate the usage of SOM for topic categorization. The first set of documents is a collection of speeches given by Y.C. Wang, Chairman of the Taiwan Plastics Group, and the other is the collection of all laws and regulations related to securities and future markets in Taiwan. We also try to apply text mining to these two sets of documents to generate their respective topic maps, thus revealing the differences between organizing explicit and tacit knowledge as well as the difficulties associated with tacit knowledge.[Article content in Chinese

  2. Sodium ascorbyl phosphate in topical microemulsions.

    Science.gov (United States)

    Spiclin, Polona; Homar, Miha; Zupancic-Valant, Andreja; Gasperlin, Mirjana

    2003-04-30

    Sodium ascorbyl phosphate is a hydrophilic derivative of ascorbic acid, which has improved stability arising from its chemical structure. It is used in cosmetic and pharmaceutical preparations since it has many favorable effects in the skin, the most important being antioxidant action. In order to achieve this, it has to be converted into free ascorbic acid by enzymatic degradation in the skin. In the present work, o/w and w/o microemulsions composed of the same ingredients, were selected as carrier systems for topical delivery of sodium ascorbyl phosphate. We showed that sodium ascorbyl phosphate was stable in both types of microemulsion with no significant influence of its location in the carrier system. To obtain liquid microemulsions appropriate for topical application, their viscosity was increased by adding thickening agents. On the basis of rheological characterization, 4.00% (m/m) colloidal silica was chosen as a suitable thickening agent for w/o microemulsions and 0.50% (m/m) xanthan gum for the o/w type. The presence of thickening agent and the location of sodium ascorbyl phosphate in the microemulsion influenced the in vitro drug release profiles. When incorporated in the internal aqueous phase, sustained release profiles were observed. This study confirmed microemulsions as suitable carrier systems for topical application of sodium ascorbyl phosphate.

  3. Tracking Multiple Topics for Finding Interesting Articles

    Energy Technology Data Exchange (ETDEWEB)

    Pon, R K; Cardenas, A F; Buttler, D J; Critchlow, T J

    2008-01-03

    We introduce multiple topic tracking (MTT) for iScore to better recommend news articles for users with multiple interests and to address changes in user interests over time. As an extension of the basic Rocchio algorithm, traditional topic detection and tracking, and single-pass clustering, MTT maintains multiple interest profiles to identify interesting articles for a specific user given user-feedback. Focusing on only interesting topics enables iScore to discard useless profiles to address changes in user interests and to achieve a balance between resource consumption and classification accuracy. iScore is able to achieve higher quality results than traditional methods such as the Rocchio algorithm. We identify several operating parameters that work well for MTT. Using the same parameters, we show that MTT alone yields high quality results for recommending interesting articles from several corpora. The inclusion of MTT improves iScore's performance by 25% in recommending news articles from the Yahoo! News RSS feeds and the TREC11 adaptive filter article collection. And through a small user study, we show that iScore can still perform well when only provided with little user feedback.

  4. Armenian media coverage of science topics

    Science.gov (United States)

    Mkhitaryan, Marie

    2016-12-01

    The article discusses features and issues of Armenian media coverage on scientific topics and provides recommendations on how to promote scientific topics in media. The media is more interested in social or public reaction rather than in scientific information itself. Medical science has a large share of the global media coverage. It is followed by articles about environment, space, technology, physics and other areas. Armenian media mainly tends to focus on a scientific topic if at first sight it contains something revolutionary. Media primarily reviews whether that scientific study can affect the Armenian economy and only then decides to refer to it. Unfortunately, nowadays the perception of science is a little distorted in media. We can often see headlines of news where is mentioned that the scientist has made "an invention". Nowadays it is hard to see the border between a scientist and an inventor. In fact, the technological term "invention" attracts the media by making illusionary sensation and ensuring large audience. The report also addresses the "Gitamard" ("A science-man") special project started in 2016 in Mediamax that tells about scientists and their motivations.

  5. Semantic Segmentation with Same Topic Constraints

    Directory of Open Access Journals (Sweden)

    Ling Mao

    2013-02-01

    Full Text Available A popular approach to semantic segmentation problems is to construct a pair wise Conditional Markov Random Field (CRF over image pixels where the pair wise term encodes a preference for smoothness within pixel neighborhoods. Recently, researchers have considered higher-order models that encode local region or soft non-local constraints (e.g., label consistency or co-occurrence statistics. These new models with higher-order terms have significantly pushed the state-of-the-art for semantic segmentation problems. In this study, we consider a novel non-local constraint that enforces consistent pixel labels among those image regions having the same topic. These topics are discovered by Probabilistic Latent Semantic Analysis model (PLSA. We encode this constraint as a robust Pn higher-order potential among all the image regions of the same topic in a unified CRF model. We experimentally demonstrate quantitative and qualitative improvements over a refined baseline unary and pair wise CRF models.

  6. A New Generalized Similarity-Based Topic Distillation Algorithm

    Institute of Scientific and Technical Information of China (English)

    ZHOU Hongfang; DANG Xiaohui

    2007-01-01

    The procedure of hypertext induced topic search based on a semantic relation model is analyzed, and the reason for the topic drift of HITS algorithm was found to prove that Web pages are projected to a wrong latent semantic basis. A new concept-generalized similarity is introduced and, based on this, a new topic distillation algorithm GSTDA(generalized similarity based topic distillation algorithm) was presented to improve the quality of topic distillation. GSTDA was applied not only to avoid the topic drift, but also to explore relative topics to user query. The experimental results on 10 queries show that GSTDA reduces topic drift rate by 10% to 58% compared to that of HITS(hypertext induced topic search) algorithm, and discovers several relative topics to queries that have multiple meanings.

  7. Intelligent topical sentiment analysis for the classification of e-learners and their topics of interest.

    Science.gov (United States)

    Ravichandran, M; Kulanthaivel, G; Chellatamilan, T

    2015-01-01

    Every day, huge numbers of instant tweets (messages) are published on Twitter as it is one of the massive social media for e-learners interactions. The options regarding various interesting topics to be studied are discussed among the learners and teachers through the capture of ideal sources in Twitter. The common sentiment behavior towards these topics is received through the massive number of instant messages about them. In this paper, rather than using the opinion polarity of each message relevant to the topic, authors focus on sentence level opinion classification upon using the unsupervised algorithm named bigram item response theory (BIRT). It differs from the traditional classification and document level classification algorithm. The investigation illustrated in this paper is of threefold which are listed as follows: (1) lexicon based sentiment polarity of tweet messages; (2) the bigram cooccurrence relationship using naïve Bayesian; (3) the bigram item response theory (BIRT) on various topics. It has been proposed that a model using item response theory is constructed for topical classification inference. The performance has been improved remarkably using this bigram item response theory when compared with other supervised algorithms. The experiment has been conducted on a real life dataset containing different set of tweets and topics.

  8. Intelligent Topical Sentiment Analysis for the Classification of E-Learners and Their Topics of Interest

    Directory of Open Access Journals (Sweden)

    M. Ravichandran

    2015-01-01

    Full Text Available Every day, huge numbers of instant tweets (messages are published on Twitter as it is one of the massive social media for e-learners interactions. The options regarding various interesting topics to be studied are discussed among the learners and teachers through the capture of ideal sources in Twitter. The common sentiment behavior towards these topics is received through the massive number of instant messages about them. In this paper, rather than using the opinion polarity of each message relevant to the topic, authors focus on sentence level opinion classification upon using the unsupervised algorithm named bigram item response theory (BIRT. It differs from the traditional classification and document level classification algorithm. The investigation illustrated in this paper is of threefold which are listed as follows: (1 lexicon based sentiment polarity of tweet messages; (2 the bigram cooccurrence relationship using naïve Bayesian; (3 the bigram item response theory (BIRT on various topics. It has been proposed that a model using item response theory is constructed for topical classification inference. The performance has been improved remarkably using this bigram item response theory when compared with other supervised algorithms. The experiment has been conducted on a real life dataset containing different set of tweets and topics.

  9. Topic-Focus Articulation of Isotopy

    Directory of Open Access Journals (Sweden)

    Radim Sova

    2012-09-01

    Full Text Available The paper deals with linguistic phenomena at suprasentential level. In particular, it looks into how textual analysis can be enhanced by supplementing the Parisian programme of interpretive semantics, as devised by François Rastier, namely his theory of isotopies, with elementary aspects of topic-focus articulation (TFA, as well as contextual boundness (CB and contextual non-boundness (CN, as elaborated within the Praguian linguistic tradition (V. Mathesius, P. Sgall, E. Hajičová, F. Daneš, J. Firbas, and how the descriptive power of the former can be increased by the latter. In this respect, it is argued that two types of TFA phenomena interact during any process of textual interpretation: those of topic-focus articulation at the level of sentence, conceiving lexical morphs as thematic (T and/or rhematic (R, as well as contextually bound (CB and/or contextually non-bound (CN, and those of topic-focus articulation at the level of isotopy, with each isotopy being conceived as structured around a center (an abstract semantic unit and periphery (a span of concrete utterances. Two types of such interaction are described, each defined by either correlation, or non-correlation of the CB and CN semes at the levels of isotopy and sentence, respectively: thematic-rhematic isotopy, induced by co-occurrence of the CB seme of the center and the CB seme of the periphery; and thematic-rhematic allotopy (i.e. non-isotopy, induced by co-occurrence of the CB seme of the center and the CN seme of the periphery. Since topic-focus isotopies and allotopies can be perceived as members of privative oppositions, a tentative system of such oppositions is presented, based on linguistic analyses of selected European Commission texts drafted in English and their Czech translations. The author’s ultimate intention is to show that the semantic features of topic-focus articulation at the sentential and suprasentential levels are both structurally parallel and

  10. 1988 Annual water management plan

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Ruby Lake NWR 1987 Annual Water Management Report 1988 Annual Water Management Plan. Includes 1987 weather summary, water availability forecast, summary of 1987...

  11. Summary of the Topical Workshop on Top Quark Differential Distributions 2014

    CERN Document Server

    Czakon, Michal; Rojo, Juan

    2015-01-01

    We summarise the Topical Workshop on Top Quark Differential Distributions 2014, which took place in Cannes immediately before the annual Top2014 conference. The workshop was motivated by the availability of top quark differential distributions at NNLO and the forthcoming LHC 13 TeV data. The main goal of the workshop was to explore the impact of improved calculations of top quark production on precision LHC measurements, PDF determinations and searches for physics beyond the Standard Model, as well as finding ways in which the high precision data from ATLAS, CMS and LHCb can be used to further refine theoretical predictions for top production.

  12. Topical corticosteroids: clinical pharmacology and therapeutic use.

    Science.gov (United States)

    Miller, J A; Munro, D D

    1980-02-01

    The development of topical corticosteroids has enabled many dermatoses to be more effectively treated than previously, but there is also no doubt that misuse of these preparations can lead to troublesome local effects and potentially serious systemic problems. The most effective assay for comparing different compounds has been their vasoconstrictive activity, and this on the whole correlates well with clinical effect. To be effective, corticosteroid must be absorbed and the importance of concentration, occlusion, the type of vehicle, added penetrants such as urea and the anatomical site, on the amount of absorption and therefore on clinical activity has been demonstrated. Ointments have been shown to be more effective than creams but because of the considerable choice of potencies now available most dermatologists tend to prescribe the different formulations according to the wishes of the patient. For the same reason, dilution of the commercially marketed preparations is now not generally recommended. The main therapeutic activity of topical corticosteroids is their nonspecific anti-inflammatory effect, thought to be primarily a result of their action on the chemical mediators of inflammation. They have also been shown to be antimitotic which may well be relevant not only to the treatment of scaling dermatoses but also to their dermal thinning effect resulting from inhibition of fibroblasts. Combinations of corticosteroids with antibacterial and antifungal agents have been shown to be very effective in flexural eruptions and secondarily infected dermatoses. As a general rule, the use of topical corticosteroids in outpatients, unless badly misused, is not associated with any significant risk of adrenal axis suppression, but care must be exercised as to the amount prescribed, especially if large areas of the body are to be treated with highly potent preparations. Certain groups such as young children and patients with liver failure, and certain anatomical sites such

  13. Topical Application of Fingolimod Perturbs Cutaneous Inflammation.

    Science.gov (United States)

    Sun, Wai Y; Dimasi, David P; Pitman, Melissa R; Zhuang, YiZhong; Heddle, Robert; Pitson, Stuart M; Grimbaldeston, Michele A; Bonder, Claudine S

    2016-05-01

    The prevalence of allergies, including rhinitis, eczema, and anaphylaxis, is rising dramatically worldwide. This increase is especially problematic in children who bear the greatest burden of this rising trend. Increasing evidence identifies neutrophils as primary perpetrators of the more severe and difficult to manage forms of inflammation. A newly recognized mechanism by which neutrophils are recruited during the early phase of histamine-induced inflammation involves the sphingosine kinase (SK)/sphingosine-1-phosphate axis. This study examines whether topical application of fingolimod, an established SK/sphingosine-1-phosphate antagonist already in clinical use to treat multiple sclerosis, may be repurposed to treat cutaneous inflammation. Using two mouse models of ear skin inflammation (histamine- and IgE-mediated passive cutaneous anaphylaxis) we topically applied fingolimod prophylactically, as well as after establishment of the inflammatory response, and examined ear swelling, SK activity, vascular permeability, leukocyte recruitment, and production of proinflammatory mediators. The present study reveals that when applied topically, fingolimod attenuates both immediate and late-phase responses to histamine with reduced extravasation of fluid, SK-1 activity, proinflammatory cytokine and chemokine production, and neutrophil influx and prevents ear swelling. Intravital microscopy demonstrates that histamine-induced neutrophil rolling and adhesion to the postcapillary venules in the mouse ears is significantly attenuated even after 24 h. More importantly, these effects are achievable even once inflammation is established. Translation into humans was also accomplished with epicutaneous application of fingolimod resolving histamine-induced and allergen-induced inflammatory reactions in forearm skin. Overall, this study demonstrates, to our knowledge for the first time, that fingolimod may be repurposed to treat cutaneous inflammation.

  14. Corneal Neurotoxicity Due to Topical Benzalkonium Chloride

    Science.gov (United States)

    Sarkar, Joy; Chaudhary, Shweta; Namavari, Abed; Ozturk, Okan; Chang, Jin-Hong; Yco, Lisette; Sonawane, Snehal; Khanolkar, Vishakha; Hallak, Joelle; Jain, Sandeep

    2012-01-01

    Purpose. The aim of this study was to determine and characterize the effect of topical application of benzalkonium chloride (BAK) on corneal nerves in vivo and in vitro. Methods. Thy1-YFP+ neurofluorescent mouse eyes were treated topically with vehicle or BAK (0.01% or 0.1%). Wide-field stereofluorescence microscopy was performed to sequentially image the treated corneas in vivo every week for 4 weeks, and changes in stromal nerve fiber density (NFD) and aqueous tear production were determined. Whole-mount immunofluorescence staining of corneas was performed with antibodies to axonopathy marker SMI-32. Western immunoblot analyses were performed on trigeminal ganglion and corneal lysates to determine abundance of proteins associated with neurotoxicity and regeneration. Compartmental culture of trigeminal ganglion neurons was performed in Campenot devices to determine whether BAK affects neurite outgrowth. Results. BAK-treated corneas exhibited significantly reduced NFD and aqueous tear production, and increased inflammatory cell infiltration and fluorescein staining at 1 week (P < 0.05). These changes were most significant after 0.1% BAK treatment. The extent of inflammatory cell infiltration in the cornea showed a significant negative correlation with NFD. Sequential in vivo imaging of corneas showed two forms of BAK-induced neurotoxicity: reversible neurotoxicity characterized by axonopathy and recovery, and irreversible neurotoxicity characterized by nerve degeneration and regeneration. Increased abundance of beta III tubulin in corneal lysates confirmed regeneration. A dose-related significant reduction in neurites occurred after BAK addition to compartmental cultures of dissociated trigeminal ganglion cells. Although both BAK doses (0.0001% and 0.001%) reduced nerve fiber length, the reduction was significantly more with the higher dose (P < 0.001). Conclusion. Topical application of BAK to the eye causes corneal neurotoxicity, inflammation, and reduced aqueous

  15. Topically applied ceramide accumulates in skin glyphs

    Directory of Open Access Journals (Sweden)

    Zhang Q

    2015-07-01

    Full Text Available Qihong Zhang,1 Carol R Flach,1 Richard Mendelsohn,1 Guangru Mao,2 Apostolos Pappas,2 M Catherine Mack,2 Russel M Walters,2 Michael D Southall2 1Department of Chemistry, Rutgers University, Newark, 2Johnson & Johnson Consumer Companies, Inc., Skillman, NJ, USAAbstract: Ceramides (CERs, structural components of the stratum corneum (SC, impart essential barrier properties to this thin outer layer of the epidermis. Variations in CER species within this layer have been linked to several skin diseases. A recent proliferation of CER-containing topical skin-care products warrants the elucidation of CER penetration profiles in both healthy and diseased skin. In the current study, the spatial distributions of CER concentration profiles, following topical application of two species of CER, were tracked using infrared imaging. Suspensions of single-chain perdeuterated sphingosine and phytosphingosine CER in oleic acid were applied, in separate experiments, to the surface of healthy intact ex vivo human skin using Franz diffusion cells. Following either a 24- or 48-hour incubation period at 34°C, infrared images were acquired from microtomed skin sections. Both CER species accumulated in glyph regions of the skin and penetrated into the SC, to a limited extent, only in these regions. The concentration profiles observed herein were independent of the CER species and incubation time utilized in the study. As a result, a very heterogeneous, sparse, spatial distribution of CERs in the SC was revealed. In contrast, oleic acid was found to be fairly homogeneously distributed throughout the SC and viable epidermis, albeit at lower concentrations in the latter. A more uniform, lateral distribution of CERs in the SC would likely be important for barrier efficacy or enhancement.Keywords: stratum corneum, infrared imaging, topical delivery, oleic acid

  16. Traditional Persian topical medications for gastrointestinal diseases

    Directory of Open Access Journals (Sweden)

    Laleh Dehghani Tafti

    2017-03-01

    Full Text Available Drug delivery across the skin is used for several millennia to ease gastrointestinal (GI ailments in Traditional Persian Medicine (TPM. TPM topical remedies are generally being applied on the stomach, lower abdomen, lower back and liver to alleviate GI illnesses such as dyspepsia, gastritis, GI ulcers, inflammatory bowel disease, intestinal worms and infections. The aim of the present study is to survey the topical GI remedies and plant species used as ingredients for these remedies in TPM. In addition, pharmacological activities of the mentioned plants have been discussed. For this, we searched major TPM textbooks to find plants used to cure GI problems in topical use. Additionally, scientific databases were searched to obtain pharmacological data supporting the use of TPM plants in GI diseases. Rosa × damascena, Pistacia lentiscus, Malus domestica, Olea europaea and Artemisia absinthium are among the most frequently mentioned ingredients of TPM remedies. β-asarone, amygdalin, boswellic acids, guggulsterone, crocin, crocetin, isomasticadienolic acid, and cyclotides are the most important phytochemicals present in TPM plants with GI-protective activities. Pharmacological studies demonstrated GI activities for TPM plants supporting their extensive traditional use. These plants play pivotal role in alleviating GI disorders through exhibiting numerous activities including antispasmodic, anti-ulcer, anti-secretory, anti-colitis, anti-diarrheal, antibacterial and anthelmintic properties. Several mechanisms underlie these activities including the alleviation of oxidative stress, exhibiting cytoprotective activity, down-regulation of the inflammatory cytokines, suppression of the cellular signaling pathways of inflammatory responses, improving re-epithelialization and angiogenesis, down-regulation of anti-angiogenic factors, blocking activity of acetylcholine, etc.

  17. Petroleum marketing annual 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-08-24

    The Petroleum Marketing Annual (PMA) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysis, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the fob and landed cost of imported crude oil, and the refiners` acquisition cost of crude oil. Refined petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensures the accuracy, quality, and confidentiality of the published data in the Petroleum Marketing Annual. For this production, all estimates have been recalculated since their earlier publication in the Petroleum Marketing Monthly (PMM). These calculations made use of additional data and corrections that were received after the PMM publication date.

  18. NAGRA Annual report 2010

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-04-15

    This annual report presents the highlights of the activities carried out by the Swiss National Co-operative for the Disposal of Radioactive Wastes NAGRA during the year 2010. These include reviews by various commissions of the NAGRA co-operative's proposals for possible sites for nuclear waste repositories. Also, the enhancements made concerning information facilities for the general public at the co-operative's rock laboratories are mentioned. The operation of initial satellite-based precision measurement systems for movements in the earth's crust is noted. Organisational aspects and international co-operation are discussed. This annual report also looks at NAGRA's organisational structures and its commercial accounts. Appendices provide details on waste inventories and volumes and publications made in 2010. A selection of relevant internet addresses is also provided

  19. Renewable energy annual 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-01

    The Renewable Energy Annual 1995 is the first in an expected series of annual reports the Energy Information Administration (EIA) intends to publish to provide a comprehensive assessment of renewable energy. This report presents the following information on the history, status, and prospects of renewable energy data: estimates of renewable resources; characterizations of renewable energy technologies; descriptions of industry infrastructures for individual technologies; evaluations of current market status; and assessments of near-term prospects for market growth. An international section is included, as well as two feature articles that discuss issues of importance for renewable energy as a whole. The report also contains a number of technical appendices and a glossary. The renewable energy sources included are biomass (wood), municipal solid waste, biomass-derived liquid fuels, geothermal, wind, and solar and photovoltaic.

  20. Annual Energy Review 2007

    Energy Technology Data Exchange (ETDEWEB)

    Seiferlein, Katherine E. [USDOE Energy Information Administration (EIA), Washington, DC (United States)

    2008-06-01

    The Annual Energy Review (AER) is the Energy Information Administration's (EIA) primary report of annual historical energy statistics. For many series, data begin with the year 1949. Included are data on total energy production, consumption, and trade; overviews of petroleum, natural gas, coal, electricity, nuclear energy, renewable energy, international energy, as well as financial and environment indicators; and data unit conversion tables. Publication of this report is required under Public Law 95–91 (Department of Energy Organization Act), Section 205(c), and is in keeping with responsibilities given to the EIA under Section 205(a)(2), which states: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....”

  1. Coal industry annual 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-01

    Coal Industry Annual 1997 provides comprehensive information about US coal production, number of mines, prices, productivity, employment, productive capacity, and recoverable reserves. US Coal production for 1997 and previous years is based on the annual survey EIA-7A, Coal Production Report. This report presents data on coal consumption, coal distribution, coal stocks, coal prices, and coal quality for Congress, Federal and State agencies, the coal industry, and the general public. Appendix A contains a compilation of coal statistics for the major coal-producing States. This report includes a national total coal consumption for nonutility power producers that are not in the manufacturing, agriculture, mining, construction, or commercial sectors. 14 figs., 145 tabs.

  2. Annual General Asssembly

    CERN Multimedia

    Pension Fund

    2005-01-01

    All members and beneficiaries of the Pension Fund are invited to attend the Annual General Asssembly to be held in the CERN Council Chamber on Thursday 13 October 2005 at 14:30 The Agenda comprises: Opening Remarks (J. Bezemer) Results and presentation of the Annual Report 2004 - Role of asset classes in pension funds (C. Cuénoud). Copies of the 2004 Report are available from departmental secretariats. Package of measures aiming at equilibrating the Fund - Proposals by the Governing Board (J.-P. Matheys). Questions from members and beneficiaries. Persons wishing to ask questions are encouraged to submit them, where possible, in writing in advance, addressed to Mr C. Cuénoud, Administrator of the Fund. Conclusions (J. Bezemer). As usual, participants are invited to drinks after the assembly. NB The minutes of the 2004 General Assembly are available from the Administration of the Fund (tel.(+4122)767 27 42; e-mail Sophia.Revol@cern.ch)

  3. Annual General Asssembly

    CERN Multimedia

    2005-01-01

    All members and beneficiaries of the Pension Fund are invited to attend the Annual General Asssembly to be held in the CERN Council Chamber on Thursday 13 October 2005 at 14:30 The Agenda comprises: Opening Remarks (J. Bezemer) Results and presentation of the Annual Report 2004 - Role of asset classes in pension funds (C. Cuénoud) Copies of the 2004 Report are available from departmental secretariats. Package of measures aiming at equilibrating the Fund - Proposals by the Governing Board (J.-P. Matheys) Questions from members and beneficiaries Persons wishing to ask questions are encouraged to submit them, where possible, in writing in advance, addressed to Mr C. Cuénoud, Administrator of the Fund. Conclusions (J. Bezemer) As usual, participants are invited to drinks after the assembly. NB The minutes of the 2004 General Assembly are available from the Administration of the Fund (tel.(+4122)767 27 42; e-mail Sophia.Revol@cern.ch)

  4. International energy annual 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-04-01

    The International Energy Annual presents an overview of key international energy trends for production, consumption, imports, and exports of primary energy commodities in over 220 countries, dependencies, and areas of special sovereignty. Also included are population and gross domestic product data, as well as prices for crude oil and petroleum products in selected countries. Renewable energy reported in the International Energy Annual includes hydroelectric power and geothermal, solar, and wind electric power. Also included are biomass electric power for Brazil and the US, and biomass, geothermal, and solar energy produced in the US and not used for electricity generation. This report is published to keep the public and other interested parties fully informed of primary energy supplies on a global basis. The data presented have been largely derived from published sources. The data have been converted to units of measurement and thermal values (Appendices E and F) familiar to the American public. 93 tabs.

  5. Preface to Special Topic: Marine Renewable Energy

    Energy Technology Data Exchange (ETDEWEB)

    Pinto, F. T.; Iglesias, G.; Santos, P. R.; Deng, Zhiqun

    2015-12-30

    Marine renewable energy (MRE) is generates from waves, currents, tides, and thermal resources in the ocean. MRE has been identified as a potential commercial-scale source of renewable energy. This special topic presents a compilation of works selected from the 3rd IAHR Europe Congress, held in Porto, Portugal, in 2014. It covers different subjects relevant to MRE, including resource assessment, marine energy sector policies, energy source comparisons based on levelized cost, proof-of-concept and new-technology development for wave and tidal energy exploitation, and assessment of possible inference between wave energy converters (WEC).

  6. Recent topics in differential and analytic geometry

    CERN Document Server

    Ochiai, T

    1990-01-01

    Advanced Studies in Pure Mathematics, Volume 18-I: Recent Topics in Differential and Analytic Geometry presents the developments in the field of analytical and differential geometry. This book provides some generalities about bounded symmetric domains.Organized into two parts encompassing 12 chapters, this volume begins with an overview of harmonic mappings and holomorphic foliations. This text then discusses the global structures of a compact Kähler manifold that is locally decomposable as an isometric product of Ricci-positive, Ricci-negative, and Ricci-flat parts. Other chapters con

  7. TOPICAL REVIEW: Nanoscience and nanotechnology in Europe

    Science.gov (United States)

    Tolles, W. M.

    1996-06-01

    During six months from April to September 1994, the author visited 42 laboratories in eight different European countries involved with research in nanostructures. The scientific thrusts point the way to new methods and properties of matter that may provide useful information. The potential applications of research in this field are likely to be found in information technology, sensors, and new materials, replete with the implications for many industrial interests. It is a suitable topic for the recently introduced `focused technical assessment' activities of the Office of Naval Research Europe where the coordination for this effort was focused. Overviews of multidisciplinary efforts in fields of physics, electrical engineering, materials, chemistry, and biology are presented.

  8. Update on key topics in adolescent gynecology.

    Science.gov (United States)

    Fisher, Martin; Lara-Torre, Eduardo

    2013-02-01

    AM:STARs, the Adolescent Medicine State of the Art Reviews series published by the American Academy of Pediatrics, devoted its April 2012 issue to the topic of Adolescent Gynecology. Developed in conjunction with the North American Society for Pediatric and Adolescent Gynecology (NASPAG), the issue consists of twelve articles, written mostly by members of NASPAG. As editors of the issue, we present in this review for the Journal of Pediatric and Adolescent Gynecology (JPAG) a synopsis of the most salient concepts presented in those 12 articles. This review of reviews is intended to be an update on the "state of the art" in adolescent gynecology.

  9. Topics in multivariate approximation and interpolation

    CERN Document Server

    Jetter, Kurt

    2005-01-01

    This book is a collection of eleven articles, written by leading experts and dealing with special topics in Multivariate Approximation and Interpolation. The material discussed here has far-reaching applications in many areas of Applied Mathematics, such as in Computer Aided Geometric Design, in Mathematical Modelling, in Signal and Image Processing and in Machine Learning, to mention a few. The book aims at giving a comprehensive information leading the reader from the fundamental notions and results of each field to the forefront of research. It is an ideal and up-to-date introduction for gr

  10. Special design topics in digital wideband receivers

    CERN Document Server

    Tsui, James B Y

    2009-01-01

    Offering engineers a thorough examination of special, more advanced aspects of digital wideband receiver design, this practical book builds on fundamental resources on the topic, helping you gain a more comprehensive understanding of the subject. This in-depth volume presents a detailed look at a complete receiver design, including the encoder. Moreover, it discusses the detection of exotic signals and provides authoritative guidance on designing receivers used in electronic warfare. From frequency modulation and biphase shifting keys, to parameter encoders in electronic warfare receivers and

  11. Topical rapamycin (sirolimus) for facial angiofibromas.

    Science.gov (United States)

    Madke, Bhushan

    2013-01-01

    Rapamycin (sirolimus) is a fungal fermentation product that inhibits the proper functioning of a serine/threonine protein kinase in mammalian cells eponymously named mammalian target of rapamycin, or mTOR. Rapamycin is a novel class of anticancer and immunosuppressant drugs targeting the proteins at molecular level. Rapamycin (sirolimus) is routinely incorporated in drug-eluting stents used for cardiac angioplasty. In recent years, rapamycin was found to be efficacious in managing the symptom complex of tuberous sclerosis, i.e. renal angiomyolipoma, giant cell astrocytoma and pulmonary lymphangiomyomatosis. Various investigators have also proved that topically applied rapamycin causes regression of facial angiofibromas, giving better cosmetic results.

  12. Topics in radiation dosimetry radiation dosimetry

    CERN Document Server

    1972-01-01

    Radiation Dosimetry, Supplement 1: Topics in Radiation Dosimetry covers instruments and techniques in dealing with special dosimetry problems. The book discusses thermoluminescence dosimetry in archeological dating; dosimetric applications of track etching; vacuum chambers of radiation measurement. The text also describes wall-less detectors in microdosimetry; dosimetry of low-energy X-rays; and the theory and general applicability of the gamma-ray theory of track effects to various systems. Dose equivalent determinations in neutron fields by means of moderator techniques; as well as developm

  13. Rheology of the lithosphere: selected topics.

    Science.gov (United States)

    Kirby, S.H.; Kronenberg, A.K.

    1987-01-01

    Reviews recent results concerning the rheology of the lithosphere with special attention to the following topics: 1) the flexure of the oceanic lithosphere, 2) deformation of the continental lithosphere resulting from vertical surface loads and forces applied at plate margins, 3) the rheological stratification of the continents, 4) strain localization and shear zone development, and 5) strain-induced crystallographic preferred orientations and anisotropies in body-wave velocities. We conclude with a section citing the 1983-1986 rock mechanics literature by category.-Authors

  14. Purely URL-based Topic Classification

    OpenAIRE

    Baykan, Eda; Henzinger, Monika R.; Marian, Ludmila; Weber, Ingmar

    2009-01-01

    Given only the URL of a web page, can we identify its topic? This is the question that we examine in this paper. Usually, web pages are classified using their content, but a URL-only classifier is preferable, (i) when speed is crucial, (ii) to enable content filtering before an (objectionable) web page is downloaded, (iii) when a page's content is hidden in images, (iv) to annotate hyperlinks in a personalized web browser, without fetching the target page, and (v) when a focused crawler...

  15. Quantum mechanics new approaches to selected topics

    CERN Document Server

    Lipkin, Harry J

    2007-01-01

    Acclaimed as ""excellent"" (Nature) and ""very original and refreshing"" (Physics Today), this collection of self-contained studies is geared toward advanced undergraduates and graduate students. Its broad selection of topics includes the Mössbauer effect, many-body quantum mechanics, scattering theory, Feynman diagrams, and relativistic quantum mechanics.Author Harry J. Lipkin, a well-known teacher at Israel's Weizmann Institute, takes an unusual approach by introducing many interesting physical problems and mathematical techniques at a much earlier point than in conventional texts. This meth

  16. Shock wave dynamics derivatives and related topics

    CERN Document Server

    Emanuel, George

    2012-01-01

    Working knowledge of the relations of various quantities and their derivatives across a shock wave is useful for any advanced research involving shock waves. Although these relations can be derived in principle by any diligent student of the subject, the derivations are often not trivial, and once derived, neither the approach nor the result can be confidently verified. Comprehensive and analytical, Shock Wave Dynamics: Derivatives and Related Topics includes not only the final results but also the methods, which are of great practical value as examples of mathematical procedure in this field.

  17. TIARA annual report 1999

    Energy Technology Data Exchange (ETDEWEB)

    Saidoh, Masahiro; Toraishi, Akio; Itoh, Hisayoshi [eds.] [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment] [and others

    2000-10-01

    This annual report describes research and development activities which have been performed with the JAERI TIARA (Takasaki Ion Accelerators for Advanced Radiation Application) facilities from April 1, 1999 to March 31, 2000. Summary reports of 106 papers and brief descriptions on the status of TIARA in the period are contained. A list of publications, the type of research collaborations and organization of TIARA are also given as appendices. (author)

  18. 2008 annual merit review

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2009-01-18

    The 2008 DOE Vehicle Technologies Program Annual Merit Review was held February 25-28, 2008 in Bethesda, Maryland. The review encompassed all of the work done by the Vehicle Technologies Program: a total of 280 individual activities were reviewed, by a total of just over 100 reviewers. A total of 1,908 individual review responses were received for the technical reviews, and an additional 29 individual review responses were received for the plenary session review.

  19. NSLS annual report 1984

    Energy Technology Data Exchange (ETDEWEB)

    Klaffky, R.; Thomlinson, W. (eds.)

    1984-01-01

    The first comprehensive Annual Report of the National Synchrotron Light Source comes at a time of great activity and forward motion for the facility. In the following pages we outline the management changes that have taken place in the past year, the progress that has been made in the commissioning of the x-ray ring and in the enhanced utilization of the uv ring, together with an extensive discussion of the interesting scientific experiments that have been carried out.

  20. TIARA annual report 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-11-01

    This annual report describes research activities which have been performed with the JAERI TIARA (Takasaki Ion Accelerators for Advanced Radiation Application) facilities from April 1, 1996 to March 31, 1997. Summary reports of 88 papers and 4 brief descriptions on the status of TIARA in the period are contained. A list of publications, the type of research collaborations and organization of TIARA are also given as appendices. (J.P.N.)

  1. TIARA annual report 2000

    Energy Technology Data Exchange (ETDEWEB)

    Saidoh, Masahiro; Toraishi, Akio; Namba, Hideki (eds.) [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment] [and others

    2001-11-01

    This annual report describes research and development activities which have been performed with the JAERI TIARA (Takasaki Ion Accelerators for Advanced Radiation Application) facilities from April 1, 2000 to March 31, 2001. Summary reports of 103 papers and brief descriptions on the status of TIARA in the period are contained. A list of publications, the type of research collaborations and organization of TIARA are also given as appendices. (author)

  2. Annual Pension Fund Update

    CERN Multimedia

    Pension Fund

    2011-01-01

    All members and beneficiaries of the Pension Fund are invited to attend the Annual Pension Fund Update to be held in the CERN Council Chamber on Tuesday 20 September 2011 from 10-00 to 12-00 a.m. Copies of the 2010 Financial Statements are available from departmental secretariats. Coffee and croissants will be served prior to the meeting as of 9-30 a.m.

  3. TIARA annual report 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-10-01

    This annual report describes research and development activities which have been performed with the JAERI TIARA (Takasaki Ion Accelerators for Advanced Radiation Application) facilities from April 1, 1998 to March 31, 1999. Summary reports of 95 papers and brief descriptions on the status of TIARA in the period are contained. A list of publications, the type of research collaborations and organization of TIARA are also given as appendices. (author)

  4. TIARA annual report 2001

    Energy Technology Data Exchange (ETDEWEB)

    Saidoh, Masahiro; Ohara, Yoshihiro; Namba, Hideki (eds.) [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment] [and others

    2002-11-01

    This annual report describes research and development activities which have been performed with the JAERI TIARA (Takasaki Ion Accelerators for Advanced Radiation Application) facilities from April 1, 2001 to March 31, 2002. Summary reports of 109 papers and brief descriptions on the status of TIARA in the period are contained. A list of publications, the type of research collaborations and organization of TIARA are also given as appendices. (author)

  5. NERSC 1998 annual report

    Energy Technology Data Exchange (ETDEWEB)

    Hules, John (ed.)

    1999-03-01

    This 1998 annual report from the National Scientific Energy Research Computing Center (NERSC) presents the year in review of the following categories: Computational Science; Computer Science and Applied Mathematics; and Systems and Services. Also presented are science highlights in the following categories: Basic Energy Sciences; Biological and Environmental Research; Fusion Energy Sciences; High Energy and Nuclear Physics; and Advanced Scientific Computing Research and Other Projects.

  6. Uranium industry annual 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-05-01

    The Uranium Industry Annual 1995 (UIA 1995) provides current statistical data on the U.S. uranium industry`s activities relating to uranium raw materials and uranium marketing. The UIA 1995 is prepared for use by the Congress, Federal and State agencies, the uranium and nuclear electric utility industries, and the public. It contains data for the period 1986 through 2005 as collected on the Form EIA-858, ``Uranium Industry Annual Survey``. Data collected on the ``Uranium Industry Annual Survey`` provide a comprehensive statistical characterization of the industry`s plans and commitments for the near-term future. Where aggregate data are presented in the UIA 1995, care has been taken to protect the confidentiality of company-specific information while still conveying accurate and complete statistical data. Data on uranium raw materials activities for 1986 through 1995 including exploration activities and expenditures, EIA-estimated reserves, mine production of uranium, production of uranium concentrate, and industry employment are presented in Chapter 1. Data on uranium marketing activities for 1994 through 2005, including purchases of uranium and enrichment services, enrichment feed deliveries, uranium fuel assemblies, filled and unfilled market requirements, uranium imports and exports, and uranium inventories are shown in Chapter 2. The methodology used in the 1995 survey, including data edit and analysis, is described in Appendix A. The methodologies for estimation of resources and reserves are described in Appendix B. A list of respondents to the ``Uranium Industry Annual Survey`` is provided in Appendix C. For the reader`s convenience, metric versions of selected tables from Chapters 1 and 2 are presented in Appendix D along with the standard conversion factors used. A glossary of technical terms is at the end of the report. 14 figs., 56 tabs.

  7. Annual report 1991

    Energy Technology Data Exchange (ETDEWEB)

    Broda, R.; Lesniak, L.; Malecki, P.; Stachura, Z.; Wojciechowski, H. [eds.

    1992-12-31

    The material presented describing the scientific activities of the Henryk Niewodniczanski Institute of Nuclear Physics in 1991 is the first annual report in several years.The arrangement of the report from various departments reflect the present structure of the Institute and is meant to help in the future task of reconstructing the Institute. Few guidelines proposed by the editorial board gave the individual departments much freedom in selecting the material and choosing the volume and format of presentation. (author).

  8. TIARA annual report 1997

    Energy Technology Data Exchange (ETDEWEB)

    Tanaka, Ryuichi; Saido, Masahiro; Nashiyama, Isamu [eds.] [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment] [and others

    1998-10-01

    This annual report describes research activities which have been performed with the JAERI TIARA (Takasaki Ion Accelerators for Advanced Radiation Application) facilities from April 1, 1997 to March 31, 1998. Summary reports of 90 papers and brief descriptions on the status of TIARA in the period are contained. A list of publications, the type of research collaborations and organization of TIARA are also given as appendices. (author)

  9. 2012 NASA Range Safety Annual Report

    Science.gov (United States)

    Dumont, Alan G.

    2012-01-01

    This report provides a NASA Range Safety (NRS) overview for current and potential range users. This report contains articles which cover a variety of subject areas, summaries of various NASA Range Safety Program (RSP) activities performed during the past year, links to past reports, and information on several projects that may have a profound impact on the way business will be conducted in the future. Specific topics discussed in the 2012 NASA Range Safety Annual Report include a program overview and 2012 highlights; Range Safety Training; Independent Assessments; Support to Program Operations at all ranges conducting NASA launch/flight operations; a continuing overview of emerging range safety-related technologies; and status reports from all of the NASA Centers that have Range Safety responsibilities.

  10. ADMET--Fifth Annual SMi Conference.

    Science.gov (United States)

    Comer, John E

    2010-09-01

    SMi's fifth annual ADMET Conference, held in London, included topics covering new developments in the field of ADMET. This conference report highlights selected presentations on ADME optimization in drug discovery; targeting drugs to the brain; predicting bonds that might be attacked during metabolism; treating Caco-2 membranes with vinblastine to enhance P-glycoprotein interactions; predictive ADMET in hit-to-lead optimization; structure-based studies of ADMET targets; an accelerated process for integrated drug development; building hypotheses in lead selection and optimization; supersaturation effects; the prediction of drug-drug interactions; developing a mechanism-based pharmacokinetic/pharmacodynamic model; drug transporter assays in drug discovery; time-dependent inhibition screens in early drug discovery; the system-dependent inhibition of CYP enzymes; the integrating predictive toxicology framework OpenTox; high-content analysis for predictive cytotoxicity testing; and emerging in vitro toxicity assays.

  11. Energy conversion & storage program. 1995 annual report

    Energy Technology Data Exchange (ETDEWEB)

    Cairns, E.J.

    1996-06-01

    The 1995 annual report discusses laboratory activities in the Energy Conversion and Storage (EC&S) Program. The report is divided into three categories: electrochemistry, chemical applications, and material applications. Research performed in each category during 1995 is described. Specific research topics relate to the development of high-performance rechargeable batteries and fuel cells, the development of high-efficiency thermochemical processes for energy conversion, the characterization of new chemical processes and complex chemical species, and the study and application of novel materials related to energy conversion and transmission. Research projects focus on transport-process principles, chemical kinetics, thermodynamics, separation processes, organic and physical chemistry, novel materials and deposition technologies, and advanced methods of analysis.

  12. Efinaconazole topical solution, 10%: formulation development program of a new topical treatment of toenail onychomycosis.

    Science.gov (United States)

    Bhatt, V; Pillai, R

    2015-07-01

    Transungual drug delivery of antifungals is considered highly desirable to treat common nail disorders such as onychomycosis, due to localized effects, and improved adherence resulting from minimal systemic adverse events. However, the development of effective topical therapies has been hampered by poor nail penetration. An effective topical antifungal must permeate through, and under the dense keratinized nail plate to the site of infection in the nail bed and nail matrix. We present here the formulation development program to provide effective transungual and subungual delivery of efinaconazole, the first topical broad spectrum triazole specifically developed for onychomycosis treatment. We discuss the important aspects encompassing the formulation development program for efinaconazole topical solution, 10%, focusing on its solubility in a number of solvents, in vitro penetration through the nail, and in vivo efficacy. Efinaconazole topical solution, 10% is a stable, non-lacquer, antifungal with a unique combination of ingredients added to an alcohol-based formulation to provide low surface tension and good wetting properties. This low surface tension is believed to affect effective transungual delivery of efinaconazole and believed to provide a dual mode of delivery by accessing the nail bed by wicking into the space between the nail and nail plate.

  13. Uranium industry annual 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-05

    The Uranium Industry Annual 1994 (UIA 1994) provides current statistical data on the US uranium industry`s activities relating to uranium raw materials and uranium marketing during that survey year. The UIA 1994 is prepared for use by the Congress, Federal and State agencies, the uranium and nuclear electric utility industries, and the public. It contains data for the 10-year period 1985 through 1994 as collected on the Form EIA-858, ``Uranium Industry Annual Survey.`` Data collected on the ``Uranium Industry Annual Survey`` (UIAS) provide a comprehensive statistical characterization of the industry`s activities for the survey year and also include some information about industry`s plans and commitments for the near-term future. Where aggregate data are presented in the UIA 1994, care has been taken to protect the confidentiality of company-specific information while still conveying accurate and complete statistical data. A feature article, ``Comparison of Uranium Mill Tailings Reclamation in the United States and Canada,`` is included in the UIA 1994. Data on uranium raw materials activities including exploration activities and expenditures, EIA-estimated resources and reserves, mine production of uranium, production of uranium concentrate, and industry employment are presented in Chapter 1. Data on uranium marketing activities, including purchases of uranium and enrichment services, and uranium inventories, enrichment feed deliveries (actual and projected), and unfilled market requirements are shown in Chapter 2.

  14. Topical and oral antibiotics for acne vulgaris.

    Science.gov (United States)

    Del Rosso, James Q

    2016-06-01

    Antibiotics, both oral and topical, have been an integral component of the management of acne vulgaris (AV) for approximately 6 decades. Originally thought to be effective for AV due to their ability to inhibit proliferation of Propionibacterium acnes, it is now believed that at least some antibiotics also exert anti-inflammatory effects that provide additional therapeutic benefit. To add, an increase in strains of P acnes and other exposed bacteria that are less sensitive to antibiotics used to treat AV have emerged, with resistance directly correlated geographically with the magnitude of antibiotic use. Although antibiotics still remain part of the therapeutic armamentarium for AV treatment, current recommendations support the following when used to treat AV: 1) monotherapy use should be avoided; 2) use benzoyl peroxide concomitantly to reduce emergence of resistant P acnes strains; 3) oral antibiotics should be used in combination with a topical regimen for moderate-to-severe inflammatory AV; and 4) use oral antibiotics over a limited duration to achieve control of inflammatory AV with an exit plan in place to discontinue their use as soon as possible. When selecting an oral antibiotic to treat AV, potential adverse effects are important to consider.

  15. Novel topical therapies for distal colitis

    Institute of Scientific and Technical Information of China (English)

    Ian; Craig; Lawrance

    2010-01-01

    Distal colitis(DC) can be effectively treated with topical 5ASA agents.Suppositories target the rectum while enemas can reliably reach the splenic flexure.Used in combination with oral 5ASAs,the control of the inflammation is even more effective.Unfortunately,resistant DC does occur and can be extremely challenging to manage.In these patients,the use of steroids,immunosuppressants and the anti-tumor necrosis factor α agents are often required.These,however,can be associated with systemic side effects and are not always effective.The investigation of new topical therapeutic agents is thus required as they are rarely associated with significant blood drug levels and side effects are infrequent.Some of the agents that have been proposed for use in resistant distal colitis include butyrate,cyclosporine and nicotine enemas as well as tacrolimus suppositories and tacrolimus,ecabet sodium,arsenic,lidocaine,rebamipide and Ridogrel enemas.Some of these agents have demonstrated impressive results but the majority of the agents have only been assessed in small open-labelled patient cohorts.Further work is thus required with the investigation of promising agents in the context of randomized double-blinded placebo controlled trials.This review aims to highlight those potentially effective therapies in the management of resistant distal colitis and to promote interest in furthering their investigation.

  16. Topically applied ceramide accumulates in skin glyphs

    Science.gov (United States)

    Zhang, Qihong; Flach, Carol R; Mendelsohn, Richard; Mao, Guangru; Pappas, Apostolos; Mack, M Catherine; Walters, Russel M; Southall, Michael D

    2015-01-01

    Ceramides (CERs), structural components of the stratum corneum (SC), impart essential barrier properties to this thin outer layer of the epidermis. Variations in CER species within this layer have been linked to several skin diseases. A recent proliferation of CER-containing topical skin-care products warrants the elucidation of CER penetration profiles in both healthy and diseased skin. In the current study, the spatial distributions of CER concentration profiles, following topical application of two species of CER, were tracked using infrared imaging. Suspensions of single-chain perdeuterated sphingosine and phytosphingosine CER in oleic acid were applied, in separate experiments, to the surface of healthy intact ex vivo human skin using Franz diffusion cells. Following either a 24- or 48-hour incubation period at 34°C, infrared images were acquired from microtomed skin sections. Both CER species accumulated in glyph regions of the skin and penetrated into the SC, to a limited extent, only in these regions. The concentration profiles observed herein were independent of the CER species and incubation time utilized in the study. As a result, a very heterogeneous, sparse, spatial distribution of CERs in the SC was revealed. In contrast, oleic acid was found to be fairly homogeneously distributed throughout the SC and viable epidermis, albeit at lower concentrations in the latter. A more uniform, lateral distribution of CERs in the SC would likely be important for barrier efficacy or enhancement. PMID:26170709

  17. Holography And Related Topics In String Theory

    CERN Document Server

    Thompson, D M

    2005-01-01

    This thesis covers research into the holographic entropy bound, the D-brane descent relations, and properties of AdS2 solutions in supersymmetric and nonsupersymmetric string theories. The first chapter introduces these topics and the connections between them. In chapter two, the holographic Bousso bound is studied and its modification due to quantum effects is presented. The Bousso bound requires that one quarter the area of a closed codimension two spacelike surface exceeds the entropy flux across a certain lightsheet terminating on the surface. The bound can be violated by quantum effects such as Hawking radiation. It is proposed that, at the quantum level, the bound be modified by adding to the area the quantum entanglement entropy across the surface. The validity of this quantum Bousso bound is proven in a two-dimensional large-N dilaton gravity theory. On the topic of D-branes, chapter three introduces the descent relations among branes of different dimensionality and stability. The descent relations re...

  18. Stability of ascorbyl palmitate in topical microemulsions.

    Science.gov (United States)

    Spiclin, P; Gasperlin, M; Kmetec, V

    2001-07-17

    Ascorbyl palmitate and sodium ascorbyl phosphate are derivatives of ascorbic acid, which differ in stability and hydro-lipophilic properties. They are widely used in cosmetic and pharmaceutical preparations. In the present work the stability of both derivatives was studied in microemulsions for topical use as carrier systems. The microemulsions were of both o/w and w/o types and composed of the same ingredients. The stability of the less stable derivative ascorbyl palmitate was tested under different conditions to evaluate the influence of initial concentration, location in microemulsion, dissolved oxygen and storage conditions. High concentrations of ascorbyl palmitate reduced the extent of its degradation. The location of ascorbyl palmitate in the microemulsion and oxygen dissolved in the system together significantly influence the stability of the compound. Light accelerated the degradation of ascorbyl palmitate. In contrast, sodium ascorbyl phosphate was stable in both types of microemulsions. Sodium ascorbyl phosphate is shown to be convenient as an active ingredient in topical preparations. In the case of ascorbyl palmitate, long-term stability in selected microemulsions was not adequate. To formulate an optimal carrier system for this ingredient other factors influencing the stability have to be considered.

  19. 78 FR 64912 - Annual Retail Trade Survey

    Science.gov (United States)

    2013-10-30

    ... survey, the Census Bureau will collect data covering annual sales, annual e-commerce sales, year-end... Classification System (NAICS). ARTS provides, on a comparable classification basis, annual sales, annual e... annual sales, annual e-commerce sales, year-end inventories held inside and outside the United...

  20. The Impact of Topic Congruence on Second Language Reading Comprehension

    Directory of Open Access Journals (Sweden)

    Marzieh Sadeghpour

    2013-09-01

    Full Text Available The present study scrutinized the impact of congruent topics on the quality of L2 reading comprehension. 56 Iranian advanced-level students read 2 texts on a controversial topic, one on the advantages of child gender selection, and the other on disadvantages. Quality analysis of immediate and delayed recall tasks, defined as the amount of high and low-level information recalled correctly, was performed by analysis of variance. Results revealed that topic congruence affected immediate recall of both high and low-level information, and also delayed recall of low-level information. Findings showed that the effect of congruent topics on reading recall was detrimental; participants recalled less information from the passage with congruent topic than a passage with incongruent topic. Outcomes of the study suggest that controversial topics should be selected more cautiously, because they may not truly reflect L2 readers’ reading comprehension. Keywords: congruent topic, L2 reading, readers’ attitude, immediate recall, delayed recall

  1. Topic Prominence in Japanese EFL Students' Existential Constructions.

    Science.gov (United States)

    Sasaki, Miyuki

    1990-01-01

    Investigations of Japanese speakers' interlanguage constructions of English existential sentences with a locative sentential topic found a general shift from topic-comment to subject-predicate structures as proficiency increased. (24 references) (Author/CB)

  2. Topical ketoconazole therapy in a recalcitrant case of seborrhoeic dermatitis

    Directory of Open Access Journals (Sweden)

    Baishya B

    1996-01-01

    Full Text Available Ketoconazole 2% cream and 2% shampoo were found to be effective in controlling seborrhoeic dermatitis in a recalcitrant case. This topical ketoconazole therapy seems to be better than other conventional topical preparations prescribed in seborrhoeic dermatitis.

  3. Hierarchical topic modeling with nested hierarchical Dirichlet process

    Institute of Scientific and Technical Information of China (English)

    Yi-qun DING; Shan-ping LI; Zhen ZHANG; Bin SHEN

    2009-01-01

    This paper deals with the statistical modeling of latent topic hierarchies in text corpora. The height of the topic tree is assumed as fixed, while the number of topics on each level as unknown a priori and to be inferred from data. Taking a nonparametric Bayesian approach to this problem, we propose a new probabilistic generative model based on the nested hierarchical Dirichlet process (nHDP) and present a Markov chain Monte Carlo sampling algorithm for the inference of the topic tree structure as welt as the word distribution of each topic and topic distribution of each document. Our theoretical analysis and experiment results show that this model can produce a more compact hierarchical topic structure and captures more free-grained topic relationships compared to the hierarchical latent Dirichlet allocation model.

  4. Health Topic XML File Description: MedlinePlus

    Science.gov (United States)

    ... Here: Home → Health Topic XML File Description: MedlinePlus URL of this page: https://medlineplus.gov/xmldescription.html ... on MedlinePlus: Not used for the public site. url - the topic URL. The URL for the corresponding ...

  5. 2010 NASA Range Safety Annual Report

    Science.gov (United States)

    Dumont, Alan G.

    2010-01-01

    this report provides a NASA Range Safety overview for current and potential range users. This report contains articles which cover a variety of subject areas, summaries of various NASA Range Safety Program activities conducted during the past year, links to past reports, and information on several projects that may have a profound impact on the way business will be done in the future. Specific topics discussed in the 2010 NASA Range Safety Annual Report include a program overview and 2010 highlights; Range Safety Training; Range Safety Policy revision; Independent Assessments; Support to Program Operations at all ranges conducting NASA launch/flight operations; a continuing overview of emerging range safety-related technologies; and status reports from all of the NASA Centers that have Range Safety responsibilities. Every effort has been made to include the most current information available. We recommend this report be used only for guidance and that the validity and accuracy of all articles be verified for updates. Once again, the web-based format was used to present the annual report.

  6. Extracting Topic Words from the Web for Dialogue Sentence Generation

    OpenAIRE

    下川, 尚亮; Rafal, Rzepka; 荒木, 健治

    2009-01-01

    In this paper we extract topic words from Internet Relay Chat utterances. In such dialogues there are many more spoken language expressions than in blogs or usual Web pages and we presume that the always changing topic is difficult to determine only by nouns which are usually used for topic recognition. In this paper we propose a method for determining a conversation topic considering also association adjectives and verbs retrieved from the Web. Our first experiments show that extracting asso...

  7. Modeling community structure and topics in dynamic text networks

    CERN Document Server

    Henry, Teague; Chai, Christine; Owens-Oas, Derek

    2016-01-01

    The last decade has seen great progress in both dynamic network modeling and topic modeling. This paper draws upon both areas to create a Bayesian method that allows topic discovery to inform the latent network model and the network structure to facilitate topic identification. We apply this method to the 467 top political blogs of 2012. Our results find complex community structure within this set of blogs, where community membership depends strongly upon the set of topics in which the blogger is interested.

  8. Plasmonics From Basics to Advanced Topics

    CERN Document Server

    Bonod, Nicolas

    2012-01-01

    This book deals with all aspects of plasmonics, basics, applications and advanced developments. Plasmonics is an emerging field of research dedicated to the resonant interaction of light with metals. The light/matter interaction is strongly enhanced at a nanometer scale which sparks a keen interest of a wide scientific community and offers promising applications in pharmacology, solar energy, nanocircuitry or also light sources. The major breakthroughs of this field of research originate from the recent advances in nanotechnology, imaging and numerical modelling.  The book is divided into three main parts: extended surface plasmons polaritons propagating on metallic surfaces, surface plasmons localized on metallic particles, imaging and nanofabrication techniques. The reader will find in the book: Principles and recent advances of plasmonics, a complete description of the physics of surface plasmons, a historical survey with emphasize on the emblematic topic of Wood's anomaly, an overview of modern applicati...

  9. Topics in modelling of clustered data

    CERN Document Server

    Aerts, Marc; Ryan, Louise M; Geys, Helena

    2002-01-01

    Many methods for analyzing clustered data exist, all with advantages and limitations in particular applications. Compiled from the contributions of leading specialists in the field, Topics in Modelling of Clustered Data describes the tools and techniques for modelling the clustered data often encountered in medical, biological, environmental, and social science studies. It focuses on providing a comprehensive treatment of marginal, conditional, and random effects models using, among others, likelihood, pseudo-likelihood, and generalized estimating equations methods. The authors motivate and illustrate all aspects of these models in a variety of real applications. They discuss several variations and extensions, including individual-level covariates and combined continuous and discrete outcomes. Flexible modelling with fractional and local polynomials, omnibus lack-of-fit tests, robustification against misspecification, exact, and bootstrap inferential procedures all receive extensive treatment. The application...

  10. Topical tar: Back to the future

    Energy Technology Data Exchange (ETDEWEB)

    Paghdal, K.V.; Schwartz, R.A. [University of Medicine & Dentistry of New Jersey, Newark, NJ (United States)

    2009-08-15

    The use of medicinal tar for dermatologic disorders dates back to the ancient times. Although coal tar is utilized more frequently in modern dermatology, wood tars have also been widely employed. Tar is used mainly in the treatment of chronic stable plaque psoriasis, scalp psoriasis, atopic dermatitis, and seborrheic dermatitis, either alone or in combination therapy with other medications, phototherapy, or both. Many modifications have been made to tar preparations to increase their acceptability, as some dislike its odor, messy application, and staining of clothing. One should consider a tried and true treatment with tar that has led to clearing of lesions and prolonged remission times. Occupational studies have demonstrated the carcinogenicity of tar; however, epidemiologic studies do not confirm similar outcomes when used topically. This article will review the pharmacology, formulations, efficacy, and adverse effects of crude coal tar and other tars in the treatment of selected dermatologic conditions.

  11. Research topics in Social Psychology in Brazil

    Directory of Open Access Journals (Sweden)

    Cláudio V. Torres

    2013-03-01

    Full Text Available How is the portrait of the Brazilian scientific production in Social Psychology of the past few years? This study aims to address especifically this question, by visiting the articles published by Brazilian scholars since 1980, all of whom have been recognized and sponsored by the Brazilian National Council on Scientific and Technological Development (CNPq. Production from 80 Brazilian researchers was analysed, based on phenomena traditionally studied by Social Psychologists (e.g., Social Influence, which served as a priori categories. Articles that reflect studies developed in 5 geopolitical regions of the country, but data showed regions South and Southeast with the highest concentration in terms of academic production. Such finding is discussed in terms of the influence of an individualist culture on Brazilian research. Observing the main Social Psychology topics studied by Brazilians, it was noticed a centrality of the "Psychological" approach to Social Psychology, mainly originated in English-speaking countries.

  12. Document Clustering based on Topic Maps

    CERN Document Server

    Rafi, Muhammad; Farooq, Amir; 10.5120/1640-2204

    2011-01-01

    Importance of document clustering is now widely acknowledged by researchers for better management, smart navigation, efficient filtering, and concise summarization of large collection of documents like World Wide Web (WWW). The next challenge lies in semantically performing clustering based on the semantic contents of the document. The problem of document clustering has two main components: (1) to represent the document in such a form that inherently captures semantics of the text. This may also help to reduce dimensionality of the document, and (2) to define a similarity measure based on the semantic representation such that it assigns higher numerical values to document pairs which have higher semantic relationship. Feature space of the documents can be very challenging for document clustering. A document may contain multiple topics, it may contain a large set of class-independent general-words, and a handful class-specific core-words. With these features in mind, traditional agglomerative clustering algori...

  13. Topics from Australian Conferences on Teaching Statistics

    CERN Document Server

    Phillips, Brian; Martin, Michael

    2014-01-01

    The first OZCOTS conference in 1998 was inspired by papers contributed by Australians to the 5th International Conference on Teaching Statistics. In 2008, as part of the program of one of the first National Senior Teaching Fellowships, the 6th OZCOTS was held in conjunction with the Australian Statistical Conference, with Fellowship keynotes and contributed papers, optional refereeing and proceedings. This venture was so successful that the 7th and 8th OZCOTS were similarly run, conjoined with Australian Statistical Conferences in 2010 and 2012. Authors of papers from these OZCOTS conferences were invited to develop chapters for refereeing and inclusion in this volume. There are sections on keynote topics, undergraduate curriculum and learning, professional development, postgraduate learning, and papers from OZCOTS 2012. Because OZCOTS aim to unite statisticians and statistics educators, the approaches this volume takes are immediately relevant to all who have a vested interest in good teaching practices. Glo...

  14. Affective topic model for social emotion detection.

    Science.gov (United States)

    Rao, Yanghui; Li, Qing; Wenyin, Liu; Wu, Qingyuan; Quan, Xiaojun

    2014-10-01

    The rapid development of social media services has been a great boon for the communication of emotions through blogs, microblogs/tweets, instant-messaging tools, news portals, and so forth. This paper is concerned with the detection of emotions evoked in a reader by social media. Compared to classical sentiment analysis conducted from the writer's perspective, analysis from the reader's perspective can be more meaningful when applied to social media. We propose an affective topic model with the intention to bridge the gap between social media materials and a reader's emotions by introducing an intermediate layer. The proposed model can be used to classify the social emotions of unlabeled documents and to generate a social emotion lexicon. Extensive evaluations using real-world data validate the effectiveness of the proposed model for both these applications.

  15. Current topics in summability theory and applications

    CERN Document Server

    Rhoades, Billy

    2016-01-01

    This book discusses recent developments in and contemporary research on summability theory, including general summability methods, direct theorems on summability, absolute and strong summability, special methods of summability, functional analytic methods in summability, and related topics and applications. All contributing authors are eminent scientists, researchers and scholars in their respective fields, and hail from around the world. The book can be used as a textbook for graduate and senior undergraduate students, and as a valuable reference guide for researchers and practitioners in the fields of summability theory and functional analysis. Summability theory is generally used in analysis and applied mathematics. It plays an important part in the engineering sciences, and various aspects of the theory have long since been studied by researchers all over the world. .

  16. Current topics in clinical FES in Japan.

    Science.gov (United States)

    Handa, Y

    1997-12-01

    This paper reviews recent topics of clinical application of functional electrical stimulation (FES) for the paralyzed extremities in Japan. Transcutaneous and percutaneous FES systems have been clinically used in Japan. Candidates of extremity FES arer mostly stroke and spinal cord injury patients. By using percutaneous FES system, all of the joints of the upper extremity including the shoulder have been controlled for activities of daily living in the hemiplegic patient. Simultaneous FES control of the hand and wrist and the bilateral hands have also been achieved in C5 and C6 quadriplegics, respectively. Hybrid FES systems using percutaneous and surface electrodes, where FES is used in combination with orthoses, have been applied to the paraplegics because they are highly practical for assisting their locomotive activities. Percutaneous FES have been also provided the amyotropic lateral sclerosis patients with standing up motion. A total implant FES system with 16 output channels is currently developing as a next generation FES system.

  17. Balancing Rights: Education Law in a Brave New World. Papers [of the] Education Law Association (ELA) Annual Conference (48th, New Orleans, LA, November 14-16, 2002).

    Science.gov (United States)

    Education Law Association, Dayton, OH.

    This collection contains 54 papers from the 48th annual conference of the Education Law Association held in November 2002. It has as its focus education law, yet it covers a wide variety of topics and issues affecting the entire range of education from preschool to college. Among the topics are the following: school vouchers; school safety and…

  18. Multi-Topic Tracking Model for dynamic social network

    Science.gov (United States)

    Li, Yuhua; Liu, Changzheng; Zhao, Ming; Li, Ruixuan; Xiao, Hailing; Wang, Kai; Zhang, Jun

    2016-07-01

    The topic tracking problem has attracted much attention in the last decades. However, existing approaches rarely consider network structures and textual topics together. In this paper, we propose a novel statistical model based on dynamic bayesian network, namely Multi-Topic Tracking Model for Dynamic Social Network (MTTD). It takes influence phenomenon, selection phenomenon, document generative process and the evolution of textual topics into account. Specifically, in our MTTD model, Gibbs Random Field is defined to model the influence of historical status of users in the network and the interdependency between them in order to consider the influence phenomenon. To address the selection phenomenon, a stochastic block model is used to model the link generation process based on the users' interests to topics. Probabilistic Latent Semantic Analysis (PLSA) is used to describe the document generative process according to the users' interests. Finally, the dependence on the historical topic status is also considered to ensure the continuity of the topic itself in topic evolution model. Expectation Maximization (EM) algorithm is utilized to estimate parameters in the proposed MTTD model. Empirical experiments on real datasets show that the MTTD model performs better than Popular Event Tracking (PET) and Dynamic Topic Model (DTM) in generalization performance, topic interpretability performance, topic content evolution and topic popularity evolution performance.

  19. Generative Topic Modeling in Image Data Mining and Bioinformatics Studies

    Science.gov (United States)

    Chen, Xin

    2012-01-01

    Probabilistic topic models have been developed for applications in various domains such as text mining, information retrieval and computer vision and bioinformatics domain. In this thesis, we focus on developing novel probabilistic topic models for image mining and bioinformatics studies. Specifically, a probabilistic topic-connection (PTC) model…

  20. A review of toxicity from topical salicylic acid preparations.

    Science.gov (United States)

    Madan, Raman K; Levitt, Jacob

    2014-04-01

    Topical salicylic acid is often used in dermatologic conditions because of its keratolytic, bacteriostatic, fungicidal, and photoprotective properties. The bioavailability of salicylic acid differs depending on the vehicle used and pH of transcellular fluids. Although rare, salicylic acid toxicity (salicylism) can occur from topical application. Physicians should be mindful of the potential for salicylism or even death from topically applied salicylic acid.

  1. Pharmacokinetics of topically applied sparfloxacin in rabbits

    Directory of Open Access Journals (Sweden)

    Satia Milan

    2005-01-01

    Full Text Available PURPOSE: Fluoroquinolones are antimicrobial agents that have a broad spectrum of activity and are widely used against many of the ocular pathogens, responsible for conjunctivitis, blepharitis, corneal ulcers etc. The aim of our study was to evaluate the ocular pharmacokinetics of sparfloxacin (0.3% w/v in the aqueous humour of rabbits. MATERIALS AND METHODS: Pharmacokinetics of topically administered sparfloxacin were determined after a single application of 50 µl topically. The aqueous humour samples were collected at 0, 0.25, 0.5, 1, 2, 3, 4, 5 or 6 hours after instillation. High Performance Thin Layer Chromatographic method was used to analyse the drug concentration in the aqueous humour samples. RESULTS: Fifteen minutes after the instillation of 50 µl of sparfloxacin 0.3% solution, the mean concentration in aqueous humour was found to be 1.4 µg/ml, which reaches the peak level of 3.7 µg/ml after 1.3 hours. At 6 hours, the sparfloxacin aqueous levels were 0.562 µg/ml. The clinical efficacy was predicted based on the Maximum Concentration (Cmax: Minimum Inhibitory Concentration (MIC and Area Under the Concentration-time curve (AUC:MIC ratios. CONCLUSION: The sparfloxacin levels in aqueous humour of rabbits are sufficiently high up to the 6 hours after instillation in the conjunctival sac to provide bactericidal effect against most of the ocular pathogens. Both Cmax:MIC and AUC:MIC ratios are high enough to provide bactericidal effect against most of the ocular pathogens. Sparfloxacin (0.3% ophthalmic preparation has excellent penetration through cornea.

  2. Annual Energy Review 2010

    Energy Technology Data Exchange (ETDEWEB)

    None

    2011-10-01

    This twenty-ninth edition of the Annual Energy Review (AER) presents the U.S. Energy Information Administration’s (EIA) most comprehensive look at integrated energy statistics. The summary statistics on the Nation’s energy production, consumption, trade, stocks, and prices cover all major energy commodities and all energy-consuming sectors of the U.S. economy from 1949 through 2010. The AER is EIA’s historical record of energy statistics and, because the coverage spans six decades, the statistics in this report are well-suited to long-term trend analysis.

  3. Institute annual report 2004

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    The mission of the ITU (Institute for Transuranium Elements) is to protect the European citizen against risk associated with the handling and storage of highly radioactive elements. The JRC (Joint Research Center) provide customer-driven scientific and technical support for the conception, development, implementation and monitoring of EU policies. In this framework this annual report presents the TU actions in: basic actinide research, spent fuel characterization, safety of nuclear fuels, partitioning and transmutation, alpha-immunotherapy/radiobiology, measurement of radioactivity in the environment, safeguards research and development. (A.L.B.)

  4. Nordel annual report 2003

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-06-01

    Nordel is a body for co-operation between the transmission system operators (TSO's) in Denmark, Finland, Iceland, Norway and Sweden with the primary objective to create conditions for and develop an efficient and harmonised Nordic electricity market, regardless of national borders. Furthermore, Nordel serves as forum for contact between the TSOs and representatives of the market players in the Nordic countries. The statistical part of Nordel's annual report includes data about: Exchange of electricity; Gross consumption; Electricity generation; Installed capacity; Generation of condensing power; Net consumption; Transmission capacity; Pumped storage power; Losses; Occasional power to electric boilers; Total consumption; CHP generation. (BA)

  5. NPL 1999 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    None

    2000-01-01

    OAK-B135 NPL 1999 Annual Report. The Nuclear Physics Laboratory at the University of Washington in Seattle pursues a broad program of nuclear physics research. Research activities are conducted locally and at remote sites. The current program includes ''in-house'' research on nuclear collisions using the local tandem Van de Graaff and superconducting linac accelerators as well as local and remote non-accelerator research on fundamental symmetries and weak interactions and user-mode research on relativistic heavy ions at large accelerator facilities around the world.

  6. Annual Energy Review 2001

    Energy Technology Data Exchange (ETDEWEB)

    Seiferlein, Katherine E. [USDOE Energy Information Administration (EIA), Washington, DC (United States)

    2002-11-01

    The Annual Energy Review (AER) is a statistical history of energy activities in the United States. It documents trends and milestones in U.S. energy production, trade, storage, pricing, and consumption. Each new year of data that is added to the time series—which now reach into 7 decades—extends the story of how Americans have acquired and used energy. It is a story of continual change as the Nation's economy grew, energy requirements expanded, resource availability shifted, and interdependencies developed among nations.

  7. International energy annual 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-01

    The International Energy Annual presents information and trends on world energy production and consumption for petroleum, natural gas, coal, and electricity. Production and consumption data are reported in standard units as well as British thermal units (Btu). Trade and reserves are shown for petroleum, natural gas, and coal. Data are provided on crude oil refining capacity and electricity installed capacity by type. Prices are included for selected crude oils and for refined petroleum products in selected countries. Population and Gross Domestic Product data are also provided.

  8. NERSC 2001 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Hules, John (editor)

    2001-12-12

    The National Energy Research Scientific Computing Center (NERSC) is the primary computational resource for scientific research funded by the DOE Office of Science. The Annual Report for FY2001 includes a summary of recent computational science conducted on NERSC systems (with abstracts of significant and representative projects); information about NERSC's current systems and services; descriptions of Berkeley Lab's current research and development projects in applied mathematics, computer science, and computational science; and a brief summary of NERSC's Strategic Plan for 2002-2005.

  9. Topicality and Text Pragmatic Prominence Five Hierarchies Regarding the Topic Suitability of Nominal Constituents

    DEFF Research Database (Denmark)

    Korzen, Iørn

    2015-01-01

    This paper presents and discusses a description of topicality and text pragmatic prominence of nominal discourse referents based on four hierarchies. These hierarchies concern the referent with respect to (a) its identifiability (± identifiable), (b) its referentiality (e.g. deictic, specific...

  10. Fusion Energy Division annual progress report period ending December 31, 1986

    Energy Technology Data Exchange (ETDEWEB)

    Morgan, O.B. Jr.; Berry, L.A.; Sheffield, J.

    1987-10-01

    This annual report on fusion energy discusses the progress on work in the following main topics: toroidal confinement experiments; atomic physics and plasma diagnostics development; plasma theory and computing; plasma-materials interactions; plasma technology; superconducting magnet development; fusion engineering design center; materials research and development; and neutron transport. (LSP)

  11. The energy behind the power. Southwestern Power Administration 1994 annual report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-31

    This is the Southwestern Power Administration 1994 annual report. The topics of the report include a letter to the secretary; an overview including the mission statement, a description of the Southwestern Federal Power System, financial statement, performance measurements, national performance review; year in review, summary of results, financial and statistical data and the Southwestern Power Administration Organization.

  12. AADS Annual Session and Exposition (76th, Vancouver, British Columbia, March 6-10, 1999).

    Science.gov (United States)

    Journal of Dental Education, 1999

    1999-01-01

    A proceedings summary of the American Association of Dental Schools' 76th annual meeting lists and abstracts 247 presentations on a wide variety of topics related to dental education and dental practice. Presentations are also indexed by author, subject, and keyword. (MSE)

  13. Annual Perspectives in Mathematics Education 2016: Mathematical Modeling and Modeling Mathematics

    Science.gov (United States)

    Hirsch, Christian R., Ed.; McDuffie, Amy Roth, Ed.

    2016-01-01

    Mathematical modeling plays an increasingly important role both in real-life applications--in engineering, business, the social sciences, climate study, advanced design, and more--and within mathematics education itself. This 2016 volume of "Annual Perspectives in Mathematics Education" ("APME") focuses on this key topic from a…

  14. The 14th Annual James L. Waters Symposium at Pittcon: Raman Spectroscopy

    Science.gov (United States)

    Gardner, Charles W.

    2007-01-01

    Raman Spectroscopy was the main topic of the 14th Annual James L. Waters Symposium, which was held in March 2003 at Pittcon. The development of the enabling technologies that have made Raman spectroscopy a routine analysis tool in many laboratories worldwide is discussed.

  15. Landmarks in Collective Bargaining in Higher Education. Proceedings, Seventh Annual Conference, April 1979.

    Science.gov (United States)

    Levenstein, Aaron, Ed.; Douglas, Joel M.

    The meeting of some 300 college administrators, faculty unionists, arbitrators specializing in education, and members of government agencies dealing with collective bargaining is reported in the proceedings of the Seventh Annual Conference of the National Center for the Study of Collective Bargaining in Higher Education. Topics and speakers…

  16. U.S. Department of Energy FY 1994 and 1995 annual performance report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This is the Department of Energy`s first Annual Performance Report. The topics of the report include a new era for the US DOE, sustainable energy, science and technology, national security--reducing the global nuclear danger, environmental quality, economic productivity through a competitive economy and the critical success factors--assessing the way the US DOE does business.

  17. Space Studies Board Annual Report, 2009

    Science.gov (United States)

    2009-01-01

    The year 2009 was one of transition for the nation, for NASA, and for the Space Studies Board (SSB). The nation pulled back from 2008's economic precipice, but did not return to the path of economic growth that it had been on. The United States inaugurated a new president who set out to build his administration. By mid-year President Obama had announced the appointment of Charlie Bolden as NASA administrator, and Lori Garver as deputy administrator. The president and Charlie Bolden jointly appointed an independent commission, the now well-known Augustine Commission, to provide guidance on the future of NASA's human spaceflight program. Many had known for quite a while that NASA's human spaceflight program faced a profound change at the time of the retirement of the space shuttle. This year was also a year of transition for the SSB. In 2009, Marcia Smith stepped down as staff director for both SSB and ASEB, and Dick Rowberg had a very good turn at the plate as a pinch-hitter. We are deeply indebted to both of them. We are pleased that, after a successful run as study director for Astro2010, Michael Moloney is now director of SSB and ASEB. The profound work begun in 2009 on the decadal surveys will only see the light of day later as they are released and the scientific work begins. The SSB will have much to report for 2010.

  18. Annual Energy Review 2009

    Energy Technology Data Exchange (ETDEWEB)

    Fichman, Barbara T. [USDOE Energy Information Administration (EIA), Washington, DC (United States)

    2010-08-01

    The Annual Energy Review (AER) is the U.S. Energy Information Administration's (EIA) primary report of annual historical energy statistics. For many series, data begin with the year 1949. Included are statistics on total energy production, consumption, trade, and energy prices; overviews of petroleum, natural gas, coal, electricity, nuclear energy, renewable energy, and international energy; financial and environment indicators; and data unit conversions. Publication of this report is required under Public Law 95–91 (Department of Energy Organization Act), Section 205(c), and is in keeping with responsibilities given to the EIA under Section 205(a)(2), which states: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....” The AER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. EIA welcomes suggestions from readers regarding the content of the AER and other EIA publications.

  19. Annual Energy Review 2011

    Energy Technology Data Exchange (ETDEWEB)

    Fichman, Barbara T. [USDOE Energy Information Administration (EIA), Washington, DC (United States)

    2012-09-01

    The Annual Energy Review (AER) is the U.S. Energy Information Administration's (EIA) primary report of annual historical energy statistics. For many series, data begin with the year 1949. Included are statistics on total energy production, consumption, trade, and energy prices; overviews of petroleum, natural gas, coal, electricity, nuclear energy, and renewable energy; financial and environment indicators; and data unit conversions. Publication of this report is required under Public Law 95–91 (Department of Energy Organization Act), Section 205(c), and is in keeping with responsibilities given to the EIA under Section 205(a)(2), which states: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....” The AER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. EIA welcomes suggestions from readers regarding the content of the AER and other EIA publications.

  20. Annual Energy Review 2005

    Energy Technology Data Exchange (ETDEWEB)

    Seiferlein, Katherine E. [USDOE Energy Information Administration (EIA), Washington, DC (United States)

    2006-07-01

    The Annual Energy Review (AER) is the Energy Information Administration's (EIA) primary report of annual historical energy statistics. For many series, data begin with the year 1949. Included are data on total energy production, consumption, and trade; overviews of petroleum, natural gas, coal, electricity, nuclear energy, renewable energy, international energy, as well as financial and environment indicators; and data unit conversion tables. Publication of this report is required under Public Law 95–91 (Department of Energy Organization Act), Section 205(c), and is in keeping with responsibilities given to the EIA under Section 205(a)(2), which states: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....” The AER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. EIA welcomes suggestions from readers regarding data series in the AER and in other EIA publications.

  1. Annual Energy Review 2006

    Energy Technology Data Exchange (ETDEWEB)

    Seiferlein, Katherine E. [USDOE Energy Information Administration (EIA), Washington, DC (United States)

    2007-06-01

    The Annual Energy Review (AER) is the Energy Information Administration's (EIA) primary report of annual historical energy statistics. For many series, data begin with the year 1949. Included are data on total energy production, consumption, and trade; overviews of petroleum, natural gas, coal, electricity, nuclear energy, renewable energy, international energy, as well as financial and environment indicators; and data unit conversion tables. Publication of this report is required under Public Law 95–91 (Department of Energy Organization Act), Section 205(c), and is in keeping with responsibilities given to the EIA under Section 205(a)(2), which states: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....” The AER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. EIA welcomes suggestions from readers regarding data series in the AER and in other EIA publications.

  2. CMS Annual Report 2004

    Energy Technology Data Exchange (ETDEWEB)

    de la Rubia, T D; Shang, S P; Rennie, G; Fluss, M; Westbrook, C

    2005-07-29

    Glance at the articles in this report, and you will sense the transformation that is reshaping the landscape of materials science and chemistry. This transformation is bridging the gaps among chemistry, materials science, and biology--ushering in a wealth of innovative technologies with broad scientific impact. The emergence of this intersection is reinvigorating our strategic investment into areas that build on our strength of interdisciplinary science. It is at the intersection that we position our strategic vision into a future where we will provide radical materials innovations and solutions to our national-security programs and other sponsors. Our 2004 Annual Report describes how our successes and breakthroughs follow a path set forward by our strategic plan and four organizing research themes, each with key scientific accomplishments by our staff and collaborators. We have organized this report into two major sections: research themes and our dynamic teams. The research-theme sections focus on achievements arising from earlier investments while addressing future challenges. The dynamic teams section illustrates the directorate's organizational structure of divisions, centers, and institutes that support a team environment across disciplinary and institutional boundaries. The research presented in this annual report gives substantive examples of how we are proceeding in each of these four theme areas and how they are aligned with our national-security mission. By maintaining an organizational structure that offers an environment of collaborative problem-solving opportunities, we are able to nurture the discoveries and breakthroughs required for future successes.

  3. Annual Energy Review 1993

    Energy Technology Data Exchange (ETDEWEB)

    1994-07-14

    This twelfth edition of the Annual Energy Review (AER) presents the Energy Information Administration`s historical energy statistics. For most series, statistics are given for every year from 1949 through 1993. Because coverage spans four and a half decades, the statistics in this report are well-suited to long-term trend analyses. The AER is comprehensive. It covers all major energy activities, including consumption, production, trade, stocks, and prices, for all major energy commodities, including fossil fuels and electricity. The AER also presents Energy Information Administration (EIA) statistics on some renewable energy sources. EIA estimates that its consumption series include about half of the renewable energy used in the United States. For a more complete discussion of EIA`s renewables data, see p. xix, ``Introducing Expanded Coverage of Renewable Energy Data Into the Historical Consumption Series.`` Copies of the 1993 edition of the Annual Energy Review may be obtained by using the order form in the back of this publication. Most of the data in the 1993 edition also are available on personal computer diskette. For more information about the diskettes, see the back of this publication. In addition, the data are available as part of the National Economic, Social, and Environmental Data Bank on a CD-ROM. For more information about the data bank, contact the US Department of Commerce Economics and Statistics Administration, on 202-482-1986.

  4. Annual Energy Review 2004

    Energy Technology Data Exchange (ETDEWEB)

    Seiferlein, Katherine E. [USDOE Energy Information Administration (EIA), Washington, DC (United States)

    2005-08-01

    The Annual Energy Review (AER) is the Energy Information Administration's (EIA) primary report of annual historical energy statistics. For many series, data begin with the year 1949. Included are data on total energy production, consumption, and trade; overviews of petroleum, natural gas, coal, electricity, nuclear energy, renewable energy, international energy, as well as financial and environment indicators; and data unit conversion tables. Publication of this report is required under Public Law 95–91 (Department of Energy Organization Act), Section 205(c), and is in keeping with responsibilities given to the EIA under Section 205(a)(2), which states: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....” The AER is intended for use by Members of Congress, Federal and State agencies energy analysts, and the general public. EIA welcomes suggestions from readers regarding data series in the AER and in other EIA publications.

  5. Electric power annual 1992

    Energy Technology Data Exchange (ETDEWEB)

    1994-01-06

    The Electric Power Annual presents a summary of electric utility statistics at national, regional and State levels. The objective of the publication is to provide industry decisionmakers, government policymakers, analysts and the general public with historical data that may be used in understanding US electricity markets. The Electric Power Annual is prepared by the Survey Management Division; Office of Coal, Nuclear, Electric and Alternate Fuels; Energy Information Administration (EIA); US Department of Energy. ``The US Electric Power Industry at a Glance`` section presents a profile of the electric power industry ownership and performance, and a review of key statistics for the year. Subsequent sections present data on generating capability, including proposed capability additions; net generation; fossil-fuel statistics; retail sales; revenue; financial statistics; environmental statistics; electric power transactions; demand-side management; and nonutility power producers. In addition, the appendices provide supplemental data on major disturbances and unusual occurrences in US electricity power systems. Each section contains related text and tables and refers the reader to the appropriate publication that contains more detailed data on the subject matter. Monetary values in this publication are expressed in nominal terms.

  6. ANNUAL GENERAL ASSEMBLY

    CERN Multimedia

    2001-01-01

    All members and beneficiaries of the Pension Fund are invited to attend the Annual General Asssembly to be held in the CERN Auditorium on Wednesday 3 October 2001 at 14.30 hrs The Agenda comprises:   Opening Remarks (P. Levaux) Some aspects of risk in a pension fund (C. Cuénoud) Annual Report 2000: Presentation and results (C. Cuénoud) Copies of the Report are available from divisional secretariats. Results of the actuarial reviews (G. Maurin) Questions from members and beneficiaries Persons wishing to ask questions are encouraged to submit them, where possible, in writing in advance, addressed to Mr C. Cuénoud, Administrator of the Fund. Conclusions (P. Levaux) As usual, participants are invited to drinks after the assembly. NB The minutes of the 2000 General Assembly are available from the Administration of the Fund (tel. + 41 22 767 91 94; e-mail Graziella.Praire@cern.ch) The English version will be published next week.

  7. 2004 Annual Meeting - Genes, Mutations and Disease: The Environmental Connection

    Energy Technology Data Exchange (ETDEWEB)

    Leona D. Samson, Ph.D.

    2004-08-23

    The Meeting consisted of 9 Symposia, 4 Keynote Lectures, 3 Platform Sessions and 4 Poster Sessions. In addition there were Breakfast Meetings for Special Interest Groups designed to inform attendees about the latest advances in environmental mutagenesis research. Several of the topics to be covered at this broad meeting will be of interest to the Department of Energy, Office of Science. The relevance of this meeting to the DOE derives from the fact that low dose radiation may represent one of the most significant sources of human mutations that are attributable to the environment. The EMS membership, and those who attended the EMS Annual Meeting were interested in both chemical and radiation induced biological effects, such as cell death, mutation, teratogenesis, carcinogenesis and aging. These topics thate were presented at the 2004 EMS Annual meeting that were of clear interest to DOE include: human variation in cancer susceptibility, unusual mechanisms of mutation, germ and stem cell mutagenesis, recombination and the maintenance of genomic stability, multiple roles for DNA mismatch repair, DNA helicases, mutation, cancer and aging, Genome-wide transcriptional responses to environmental change, Telomeres and genomic stability: when ends don?t meet, systems biology approach to cell phenotypic decision processes, and the surprising biology of short RNAs. Poster and platform sessions addressed topics related to environmental mutagen exposure, DNA repair, mechanisms of mutagenesis, epidemiology, genomic and proteomics and bioinformatics. These sessions were designed to give student, postdocs and more junior scientists a chance to present their workl.

  8. Impact Factors and Prediction of Popular Topics in a Journal.

    Science.gov (United States)

    Nielsen, M B; Seitz, K

    2016-08-01

    The impact factor (IF) for 2015 was recently released and this could be the time to once again reflect on its use as a metric of a journal. Problems and concerns regarding the IF have been addressed extensively elsewhere 1 2. The principle of the IF for a given year is that it represents the average number of citations of articles published in the journal in the two previous years.While authors frequently cite the IF as a determining factor for submission, the IF does not predict how many times individual articles will be cited. In a study from a peer-reviewed cardiovascular journal, nearly half of all published articles were poorly cited, i. e., less than five citations in five years 3. A similar percentage seems to apply to our journal. In nearly all journals we estimate that the majority of citations relate to a minority of the articles. Some articles are never cited. 13 % of the articles published in our journal from 2010 to 2013 have never been cited. Even authors of poorly cited articles benefit from the IF since many institutions use the combined impact factors of their published papers to measure research activity and this may be reflected in their research budgets.The competition for the printed pages in the six annual issues of Ultraschall in der Medizin/European Journal of Ultrasound (UiM/EJU) has resulted in high rejection rates (between 80 % and 90 %). One negative review with recommendation of major revision may therefore result in rejection. Peer-review fraud where the submitting author listed recommended reviewers with fake email addresses supplying fabricated peer reviews has recently been described in the New England Journal of Medicine 4. Some of the editors of our journal believe they have experienced this as well. Fabricating reviews in order to get a high IF for an article is to be considered fraud and is inexcusable.One aspect of using impact factors as a measure of the quality of a journal is that the IF only goes back two years

  9. Nuclear Physics Department annual report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-07-01

    This annual report presents articles and abstracts published in foreign journals, covering the following subjects: nuclear structure, nuclear reactions, applied physics, instrumentation, nonlinear phenomena and high energy physics

  10. Transportation Statistics Annual Report 1997

    Energy Technology Data Exchange (ETDEWEB)

    Fenn, M.

    1997-01-01

    This document is the fourth Transportation Statistics Annual Report (TSAR) prepared by the Bureau of Transportation Statistics (BTS) for the President and Congress. As in previous years, it reports on the state of U.S. transportation system at two levels. First, in Part I, it provides a statistical and interpretive survey of the system—its physical characteristics, its economic attributes, aspects of its use and performance, and the scale and severity of unintended consequences of transportation, such as fatalities and injuries, oil import dependency, and environment impacts. Part I also explores the state of transportation statistics, and new needs of the rapidly changing world of transportation. Second, Part II of the report, as in prior years, explores in detail the performance of the U.S. transportation system from the perspective of desired social outcomes or strategic goals. This year, the performance aspect of transportation chosen for thematic treatment is “Mobility and Access,” which complements past TSAR theme sections on “The Economic Performance of Transportation” (1995) and “Transportation and the Environment” (1996). Mobility and access are at the heart of the transportation system’s performance from the user’s perspective. In what ways and to what extent does the geographic freedom provided by transportation enhance personal fulfillment of the nation’s residents and contribute to economic advancement of people and businesses? This broad question underlies many of the topics examined in Part II: What is the current level of personal mobility in the United States, and how does it vary by sex, age, income level, urban or rural location, and over time? What factors explain variations? Has transportation helped improve people’s access to work, shopping, recreational facilities, and medical services, and in what ways and in what locations? How have barriers, such as age, disabilities, or lack of an automobile, affected these

  11. A New Approach to Speeding Up Topic Modeling

    CERN Document Server

    Zeng, Jia; Cao, Xiao-Qin

    2012-01-01

    Latent Dirichlet allocation (LDA) is a widely-used probabilistic topic modeling paradigm, and recently finds many applications in computer vision and computational biology. This paper proposes a fast and accurate algorithm, active belief propagation (ABP), for training LDA. Usually training LDA requires repeated scanning of the entire corpus and searching the complete topic space. Confronted with massive corpus with large number of topics, such a training iteration is often inefficient and time-consuming. To accelerate the training speed, ABP actively scans partial corpus and searches partial topic space for topic modeling, saving enormous training time in each iteration. To ensure accuracy, ABP selects only those documents and topics that contribute to the largest residuals within the residual belief propagation (RBP) framework. On four real-world corpora, ABP performs around 10 to 100 times faster than some of the major state-of-the-art algorithms for training LDA, while retains a comparable topic modeling ...

  12. Mapping the evolution of research topics using ATM and SNA

    Institute of Scientific and Technical Information of China (English)

    Chunlei; YE

    2014-01-01

    Purpose:This paper introduces an analysis framework for tracking the evolution of research topics at the selected topics level,covering a research topic’s evolution trend,evolution path and its content changes over time.Design/methodology/approach:After the topics were recovered by the author-topic model,we first built the keyword-topic co-occurrence network to track the dynamics of topic trends.Then a single-mode network was constructed with each node representing a topic and edge indicating the relationship between topics.It was used to illustrate the evolution path and content changes of research topics.A case study was conducted on the digital library research in China to verify the effectiveness of the analysis framework.Findings:The experimental results show that this analysis framework can be used to track evolution of research topics at a micro level and using social network analysis method can help understand research topics’evolution paths and content changes with the passage of time.Research limitations:Using the analysis framework will produce limited results when examining unstructured data such as social media data.In addition,the effectiveness of the framework introduced in this paper needs to be verified with more research topics in information science and in more scientific fields.Practical implications:This analysis framework can help scholars and researchers map research topics’evolution process and gain insights into how a field’s topics have evolved over time.Originality/value:Tbe analysis framework used in this study can help reveal more micro evolution details.The index to measure topic association strength defined in this paper reflects both similarity and dissimilarity between topics,which belps better understand research topics’evolution paths and content changes.

  13. Areva, annual report 2004

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This annual report contains information on AREVA objectives, prospects and strategies, particularly in chapters 4 and 7. This information is a not meant as a presentation of past performance data and should not be interpreted as a guarantee that events or data set forth herein are assured or that objectives will be met. Forward looking statements made in this document also address known and unknown risks, uncertainties and other factors that could, were they to translate into fact, cause AREVA future financial performance, operating performance and production to differ significantly from the objectives presented or suggested herein. Those factors include, in particular, changes in international, economic or market conditions, as well as risk factors presented in Section 4.14.3. Neither AREVA nor the AREVA group is committing to updating forward looking statements or information contained in the annual report. This annual report contains information on the markets, market shares and competitive position of the AREVA group. Unless otherwise indicated, all historical data and forward looking information are based on Group estimates (source: AREVA) and are provided as examples only. To AREVA knowledge, no report is available on the AREVA group markets that is sufficiently complete or objective to serve as a sole reference source. The AREVA group developed estimates based on several sources, including in-house studies and reports, statistics provided by international organizations and professional associations, data published by competitors and information collected by AREVA subsidiaries. The main sources, studies and reports used include (i) the International Atomic Energy Agency (IAEA), the International Energy Agency (IEA), the World Nuclear Association (WNA), the Nuclear Energy Institute (NEA), Nuclear Assurance Corporation (NAC), the European Atomic Energy Community (Euratom) and the Commissariat a l'Energie Atomique (CEA) for the nuclear business; and (ii

  14. Annual Energy Review 1999

    Energy Technology Data Exchange (ETDEWEB)

    Seiferlein, Katherine E. [USDOE Energy Information Administration (EIA), Washington, DC (United States)

    2000-07-01

    A generation ago the Ford Foundation convened a group of experts to explore and assess the Nation’s energy future, and published their conclusions in A Time To Choose: America’s Energy Future (Cambridge, MA: Ballinger, 1974). The Energy Policy Project developed scenarios of U.S. potential energy use in 1985 and 2000. Now, with 1985 well behind us and 2000 nearly on the record books, it may be of interest to take a look back to see what actually happened and consider what it means for our future. The study group sketched three primary scenarios with differing assumptions about the growth of energy use. The Historical Growth scenario assumed that U.S. energy consumption would continue to expand by 3.4 percent per year, the average rate from 1950 to 1970. This scenario assumed no intentional efforts to change the pattern of consumption, only efforts to encourage development of our energy supply. The Technical Fix scenario anticipated a “conscious national effort to use energy more efficiently through engineering know-how." The Zero Energy Growth scenario, while not clamping down on the economy or calling for austerity, incorporated the Technical Fix efficiencies plus additional efficiencies. This third path anticipated that economic growth would depend less on energy-intensive industries and more on those that require less energy, i.e., the service sector. In 2000, total energy consumption was projected to be 187 quadrillion British thermal units (Btu) in the Historical Growth case, 124 quadrillion Btu in the Technical Fix case, and 100 quadrillion Btu in the Zero Energy Growth case. The Annual Energy Review 1999 reports a preliminary total consumption for 1999 of 97 quadrillion Btu (see Table 1.1), and the Energy Information Administration’s Short-Term Energy Outlook (April 2000) forecasts total energy consumption of 98 quadrillion Btu in 2000. What energy consumption path did the United States actually travel to get from 1974, when the scenarios were drawn

  15. American Osteopathic College of Dermatology

    Science.gov (United States)

    ... 2013 Annual Meeting 2013 OMED Schedule Needs Assessments Speaker Bios Meeting Feedback 2014 Midyear Meeting Attestation 2014 ... Contact Us 2902 North Baltimore Street P.O. Box 7525 Kirksville, Missouri 63501 Phone: 660-665-2184 ...

  16. Analysis on Topic Maps and Its Application Case%Topic Maps及其应用实例分析

    Institute of Scientific and Technical Information of China (English)

    王秀峰; 柯青

    2010-01-01

    Topic maps是描述知识结构,建立知识结构同相关信息资源关联的ISO国际标准,可以提供最佳的信息导航.分析Topic maps概念和基本构成的基拙上,以大学信息门户Topic map的创建为例,从本体构建、Topic map定义、TAO的编码以及可视化等角度探讨了Topic maps的应用和实现技术.

  17. Topical therapy of atopic dermatitis: controversies from Hippocrates to topical immunomodulators.

    Science.gov (United States)

    Tilles, Gérard; Wallach, Daniel; Taïeb, Alain

    2007-02-01

    Although atopic dermatitis can be treated efficiently, there is still much controversy about the risk/benefit ratio of both topical corticosteroids and topical immunomodulators. Conflicting data may be found about the usefulness of bathing, diet regulation, and other therapeutic interventions. These controversies result in part from the persistence of Hippocratic doctrines in modern medical thinking. Humoralist and diathetic doctrines, as they pertain to eczema, are reviewed. The paradoxical worsening of oozing and the deadly hazards of hospitalization before the era of antibiotics are brought to mind. We hope that this historical review will improve the understanding of current controversies and help dermatologists to manage patients with atopic dermatitis and other chronic skin diseases.

  18. Generic development of topical dermatologic products, Part II: quality by design for topical semisolid products.

    Science.gov (United States)

    Chang, Rong-Kun; Raw, Andre; Lionberger, Robert; Yu, Lawrence

    2013-07-01

    The emergence of quality by design as a relatively new systematic science and risk-based approach has added a new dimension to pharmaceutical development and manufacturing. This review attempts to discuss the quality by design elements and concepts applied for topical semisolid products. Quality by design begins with defining a quality target product profile as well as critical quality attributes. Subsequently, this is followed by risk identification/risk analysis/risk evaluation to recognize critical material attributes and critical process parameters, in conjunction with design of experiments or other appropriate methods to establish control strategies for the drug product. Several design-of-experiment examples are included as practical strategies for the development and optimization of formulation and process for topical drug products.

  19. Lattice theory special topics and applications

    CERN Document Server

    Wehrung, Friedrich

    2014-01-01

    George Grätzer's Lattice Theory: Foundation is his third book on lattice theory (General Lattice Theory, 1978, second edition, 1998). In 2009, Grätzer considered updating the second edition to reflect some exciting and deep developments. He soon realized that to lay the foundation, to survey the contemporary field, to pose research problems, would require more than one volume and more than one person. So Lattice Theory: Foundation provided the foundation. Now we complete this project with Lattice Theory: Special Topics and Applications, written by a distinguished group of experts, to cover some of the vast areas not in Foundation. This first volume is divided into three parts. Part I. Topology and Lattices includes two chapters by Klaus Keimel, Jimmie Lawson and Ales Pultr, Jiri Sichler. Part II. Special Classes of Finite Lattices comprises four chapters by Gabor Czedli, George Grätzer and Joseph P. S. Kung. Part III. Congruence Lattices of Infinite Lattices and Beyond includes four chapters by Friedrich W...

  20. Mining Social Entrepreneurship Strategies Using Topic Modeling.

    Science.gov (United States)

    Chandra, Yanto; Jiang, Li Crystal; Wang, Cheng-Jun

    2016-01-01

    Despite the burgeoning research on social entrepreneurship (SE), SE strategies remain poorly understood. Drawing on extant research on the social activism and social change, empowerment and SE models, we explore, classify and validate the strategies used by 2,334 social entrepreneurs affiliated with the world's largest SE support organization, Ashoka. The results of the topic modeling of the social entrepreneurs' strategy profiles reveal that they employed a total of 39 change-making strategies that vary across resources (material versus symbolic strategies), specificity (general versus specific strategies), and mode of participation (mass versus elite participation strategies); they also vary across fields of practice and time. Finally, we identify six meta-SE strategies-a reduction from the 39 strategies-and identify four new meta-SE strategies (i.e., system reform, physical capital development, evidence-based practices, and prototyping) that have been overlooked in prior SE research. Our findings extend and deepen the research into SE strategies and offer a comprehensive model of SE strategies that advances theory, practice and policy making.

  1. Mining Social Entrepreneurship Strategies Using Topic Modeling.

    Directory of Open Access Journals (Sweden)

    Yanto Chandra

    Full Text Available Despite the burgeoning research on social entrepreneurship (SE, SE strategies remain poorly understood. Drawing on extant research on the social activism and social change, empowerment and SE models, we explore, classify and validate the strategies used by 2,334 social entrepreneurs affiliated with the world's largest SE support organization, Ashoka. The results of the topic modeling of the social entrepreneurs' strategy profiles reveal that they employed a total of 39 change-making strategies that vary across resources (material versus symbolic strategies, specificity (general versus specific strategies, and mode of participation (mass versus elite participation strategies; they also vary across fields of practice and time. Finally, we identify six meta-SE strategies-a reduction from the 39 strategies-and identify four new meta-SE strategies (i.e., system reform, physical capital development, evidence-based practices, and prototyping that have been overlooked in prior SE research. Our findings extend and deepen the research into SE strategies and offer a comprehensive model of SE strategies that advances theory, practice and policy making.

  2. Selected topics on parton distribution functions

    CERN Document Server

    Hirai, M; Kumano, S; Saito, K

    2011-01-01

    We report recent studies on structure functions of the nucleon and nuclei. First, clustering effects are investigated in the structure function F_2 of Be-9 for explaining an unusual nuclear correction found in a JLab experiment. We propose that high densities created by formation of clustering structure like 2*alpha+neutron in Be-9 is the origin of the unexpected JLab result by using the antisymmetrized molecular dynamics (AMD). There is an approved proposal at JLab to investigate the structure functions of light nuclei including the cluster structure, so that much details will become clear in a few years. Second, tensor-polarized quark and antiquark distributions are obtained by analyzing HERMES measurements on the structure function b_1 for the deuteron. The result suggests a finite tensor polarization for antiquark distributions, which is an interesting topic for further theoretical and experimental investigations. An experimental proposal exists at JLab for measuring b_1 of the deuteron as a new tensor-st...

  3. LDA boost classification: boosting by topics

    Science.gov (United States)

    Lei, La; Qiao, Guo; Qimin, Cao; Qitao, Li

    2012-12-01

    AdaBoost is an efficacious classification algorithm especially in text categorization (TC) tasks. The methodology of setting up a classifier committee and voting on the documents for classification can achieve high categorization precision. However, traditional Vector Space Model can easily lead to the curse of dimensionality and feature sparsity problems; so it affects classification performance seriously. This article proposed a novel classification algorithm called LDABoost based on boosting ideology which uses Latent Dirichlet Allocation (LDA) to modeling the feature space. Instead of using words or phrase, LDABoost use latent topics as the features. In this way, the feature dimension is significantly reduced. Improved Naïve Bayes (NB) is designed as the weaker classifier which keeps the efficiency advantage of classic NB algorithm and has higher precision. Moreover, a two-stage iterative weighted method called Cute Integration in this article is proposed for improving the accuracy by integrating weak classifiers into strong classifier in a more rational way. Mutual Information is used as metrics of weights allocation. The voting information and the categorization decision made by basis classifiers are fully utilized for generating the strong classifier. Experimental results reveals LDABoost making categorization in a low-dimensional space, it has higher accuracy than traditional AdaBoost algorithms and many other classic classification algorithms. Moreover, its runtime consumption is lower than different versions of AdaBoost, TC algorithms based on support vector machine and Neural Networks.

  4. Symmetries and fundamental interactions—selected topics

    Science.gov (United States)

    Jungmann, Klaus P.

    2014-06-01

    High precision experiments at low energies on discrete and continuous symmetries offer the possibility to search for New Physics beyond the Standard Model. Examples are dedicated searches for violations of the C, P, CP and CPT as well as of Lorentz Invariance using matter and anti-matter. Atomic parity violation was not only essential in the past to verify the Standard Model, still today it has a potential to find Z' bosons, leptoquarks or dark matter. Electric Dipole Moments (EDMs) may provide clues to explain the matter-antimatter asymmetry in the universe. There is at present a some 4 standard deviations discrepancy between theory and experiment for the muon magnetic anomaly. At the same time while providing important information on physics beyond the Standard Model, new technology such as precise clocks is developed along with the experiments motivated by fundamental physics questions. This article summarizes an overview talk that was concerned primarily with a selection of topics from a very rich field, in particular such that were not covered otherwise at this conference.

  5. Generic Development of Topical Dermatologic Products, Part II: Quality by Design for Topical Semisolid Products

    OpenAIRE

    Chang, Rong-Kun; Raw, Andre; Lionberger, Robert; Yu, Lawrence

    2013-01-01

    The emergence of quality by design as a relatively new systematic science and risk-based approach has added a new dimension to pharmaceutical development and manufacturing. This review attempts to discuss the quality by design elements and concepts applied for topical semisolid products. Quality by design begins with defining a quality target product profile as well as critical quality attributes. Subsequently, this is followed by risk identification/risk analysis/risk evaluation to recognize...

  6. Annual energy review 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-01

    This 13th edition presents the Energy Information Administration`s historical energy statistics. For most series, statistics are given for every year from 1949 through 1994; thus, this report is well-suited to long-term trend analyses. It covers all major energy activities, including consumption, production, trade, stocks, and prices for all major energy commodities, including fossil fuels and electricity. Statistics on renewable energy sources are also included: this year, for the first time, usage of renewables by other consumers as well as by electric utilities is included. Also new is a two-part, comprehensive presentation of data on petroleum products supplied by sector for 1949 through 1994. Data from electric utilities and nonutilities are integrated as ``electric power industry`` data; nonutility power gross generation are presented for the first time. One section presents international statistics (for more detail see EIA`s International Energy Annual).

  7. Coal industry annual 1993

    Energy Technology Data Exchange (ETDEWEB)

    1994-12-06

    Coal Industry Annual 1993 replaces the publication Coal Production (DOE/FIA-0125). This report presents additional tables and expanded versions of tables previously presented in Coal Production, including production, number of mines, Productivity, employment, productive capacity, and recoverable reserves. This report also presents data on coal consumption, coal distribution, coal stocks, coal prices, coal quality, and emissions for a wide audience including the Congress, Federal and State agencies, the coal industry, and the general public. In addition, Appendix A contains a compilation of coal statistics for the major coal-producing States. This report does not include coal consumption data for nonutility Power Producers who are not in the manufacturing, agriculture, mining, construction, or commercial sectors. This consumption is estimated to be 5 million short tons in 1993.

  8. Uranium Industry Annual, 1992

    Energy Technology Data Exchange (ETDEWEB)

    1993-10-28

    The Uranium Industry Annual provides current statistical data on the US uranium industry for the Congress, Federal and State agencies, the uranium and electric utility industries, and the public. The feature article, ``Decommissioning of US Conventional Uranium Production Centers,`` is included. Data on uranium raw materials activities including exploration activities and expenditures, resources and reserves, mine production of uranium, production of uranium concentrate, and industry employment are presented in Chapter 1. Data on uranium marketing activities including domestic uranium purchases, commitments by utilities, procurement arrangements, uranium imports under purchase contracts and exports, deliveries to enrichment suppliers, inventories, secondary market activities, utility market requirements, and uranium for sale by domestic suppliers are presented in Chapter 2.

  9. Nagra annual report 2007

    Energy Technology Data Exchange (ETDEWEB)

    Ammann, M. (ed.)

    2008-07-01

    This annual report issued by the Swiss National Cooperative for the Disposal of Radioactive Waste reviews the co-operative's activities in the year 2007 and presents an overview of developments in energy policy, planning procedures and funding plans. The selection of sites for the disposal of radioactive wastes in Switzerland is discussed. Various technical questions are briefly addressed and work being carried out in the rock laboratories in the Swiss Alps and Jura mountains is discussed. International co-operation is reviewed and public relations issues are discussed. Finally, organisational structures are described and the financial details for the year 2007 are presented. The report is completed with an appendix containing the co-operative's organigram, waste inventories and listings of publications, addresses and a short glossary.

  10. Nagra annual report 2008

    Energy Technology Data Exchange (ETDEWEB)

    Ammann, M. (ed.)

    2009-07-01

    This annual report issued by the Swiss National Co-operative for the Disposal of Radioactive Waste, Nagra, reviews the co-operative's activities in the year 2008 and presents an overview of developments in energy policy, planning procedures and funding plans. Energy policy and the selection of sites for the disposal of radioactive wastes in Switzerland are discussed. Various technical questions are briefly addressed and work being carried out in the rock laboratories in the Swiss Alps and Jura mountains is discussed. International co-operation is reviewed and public relations issues are discussed. Finally, organisational structures are described and Nagra's financial details for the year 2008 are presented and discussed. The report is completed with an appendix containing the co-operative's organigram, waste inventories and listings of publications, addresses and a short glossary.

  11. Uranium industry annual 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-04-01

    The Uranium Industry Annual 1996 (UIA 1996) provides current statistical data on the US uranium industry`s activities relating to uranium raw materials and uranium marketing. The UIA 1996 is prepared for use by the Congress, Federal and State agencies, the uranium and nuclear electric utility industries, and the public. Data on uranium raw materials activities for 1987 through 1996 including exploration activities and expenditures, EIA-estimated reserves, mine production of uranium, production of uranium concentrate, and industry employment are presented in Chapter 1. Data on uranium marketing activities for 1994 through 2006, including purchases of uranium and enrichment services, enrichment feed deliveries, uranium fuel assemblies, filled and unfilled market requirements, uranium imports and exports, and uranium inventories are shown in Chapter 2. A feature article, The Role of Thorium in Nuclear Energy, is included. 24 figs., 56 tabs.

  12. DANSYNC. Annual report 1996

    Energy Technology Data Exchange (ETDEWEB)

    Als-Nielsen, J.

    1997-02-01

    DANSYNC is an organisation of Danish users of hard X-ray synchrotron facilities, funded by The Danish Natural Science Research Council. It was founded in the beginning of 1996, and this is the first Annual Report from DANSYNC. Users span from basic physics at Risoe National Laboratory, Oersted Laboratory and Denmarks Technical University over materials science from Risoe National Laboratory to chemistry and biology at Aarhus University, Copenhagen University and Denmarks Technical University, as well as industrial research represented by Haldor Topsoee A/S and space research at Danish Space Research Institute. We do not have an X-ray synchrotron facility in Denmark, so all of this work is carried out at facilities abroad. Clearly the facility at DESY in Hamburg (HASYLAB and EMBL) is of the greatest significance for Danish synchrotron research. Home page: http://www.dansync.dk/dansync/. (LN).

  13. Inertial Confinement Fusion Annual Report 1997

    Energy Technology Data Exchange (ETDEWEB)

    Correll, D

    1998-06-01

    The ICF Annual Report provides documentation of the achievements of the LLNL ICF Program during the fiscal year by the use of two formats: (1) an Overview that is a narrative summary of important results for the fiscal year and (2) a compilation of the articles that previously appeared in the ICF Quarterly Report that year. Both the Overview and Quarterly Report are also on the Web at http://lasers.llnl.gov/lasers/pubs/icfq.html. Beginning in Fiscal Year 1997, the fourth quarter issue of the ICF Quarterly was no longer printed as a separate document but rather included in the ICF Annual. This change provided a more efficient process of documenting our accomplishments with-out unnecessary duplication of printing. In addition we introduced a new document, the ICF Program Monthly Highlights. Starting with the September 1997 issue and each month following, the Monthly Highlights will provide a brief description of noteworthy activities of interest to our DOE sponsors and our stakeholders. The underlying theme for LLNL's ICF Program research continues to be defined within DOE's Defense Programs missions and goals. In support of these missions and goals, the ICF Program advances research and technology development in major interrelated areas that include fusion target theory and design, target fabrication, target experiments, and laser and optical science and technology. While in pursuit of its goal of demonstrating thermonuclear fusion ignition and energy gain in the laboratory, the ICF Program provides research and development opportunities in fundamental high-energy-density physics and supports the necessary research base for the possible long-term application of inertial fusion energy for civilian power production. ICF technologies continue to have spin-off applications for additional government and industrial use. In addition to these topics, the ICF Annual Report covers non-ICF funded, but related, laser research and development and associated

  14. 1994 MCAP annual report

    Energy Technology Data Exchange (ETDEWEB)

    Harmony, S.C.; Boyack, B.E.

    1995-04-01

    VELCOR is an integrated, engineering-level computer code that models the progression of severe accidents in light water reactor (LWR) nuclear power plants. The entire spectrum of severe accident phenomena, including reactor coolant system and containment thermal-hydraulic response, core heatup, degradation and relocation, and fission product release and transport is treated in MELCOR in a unified framework for both boiling water reactors (BWRs) and pressurized water reactors (PWRs). Its current uses include the estimation of severe accident source terms and their sensitivities and uncertainties in a variety of applications. Independent assessment efforts have been successfully completed by the US and international MELCOR user communities. Most of these independent assessment efforts have been conducted to support the needs and fulfill the requirements of the individual user organizations. The resources required to perform an extensive set of model and integral code assessments are large. A prudent approach to fostering code development and maturation is to coordinate the individual assessment efforts of the MELCOR user community. While retaining individual control over assessment resources, each organization using the MELCOR code could work with the other users to broaden assessment coverage and minimize duplication. In recognition of these considerations, the US Nuclear Regulatory Commission (US NRC) has initiated the MELCOR Cooperative Assessment Program (MCAP), a vehicle for coordinating and standardizing the assessment practices of the various MELCOR users. In addition, the user community will have a forum to better communicate lessons learned regarding MELCOR applications, capabilities, and user guidelines and limitations and to provide a user community perspective on code development needs and priorities. This second Annual Report builds on the foundation laid with the first Annual Report.

  15. Medicare Update: Annual Wellness Visit

    Science.gov (United States)

    factsheet FEBRUARY 2012 Medicare Update: Annual Wellness Visit ® alz.org Under the Affordable Care Act (the health care reform law), Medicare will now pay for ... Included in the annual wellness visit: • Review and update medical and family history • Review and update a ...

  16. Tanks Focus Area FY98 midyear technical review

    Energy Technology Data Exchange (ETDEWEB)

    Schlahta, S.N.; Brouns, T.M.

    1998-06-01

    The Tanks Focus Area (TFA) serves as the DOE`s Office of Environmental Management`s national technology and solution development program for radioactive waste tank remediation. Its technical scope covers the major functions that comprise a complete tank remediation system: waste retrieval, waste pretreatment, waste immobilization, tank closure, and characterization of both the waste and tank with safety integrated into all the functions. In total, 17 technologies and technical solutions were selected for review. The purpose of each review was to understand the state of development of each technology selected for review and to identify issues to be resolved before the technology or technical solution progressed to the next level of maturity. The reviewers provided detailed technical and programmatic recommendations and comments. The disposition of these recommendations and comments and their impact on the program is documented in this report.

  17. Antibodies to watch in 2013: Mid-year update.

    Science.gov (United States)

    Reichert, Janice M

    2013-01-01

    The transitions of antibody therapeutics to late-stage clinical development, regulatory review and the market are proceeding at a rapid pace in 2013. Since late 2012, two monoclonal antibody (mAb) therapeutics (itolizumab, trastuzumab emtansine) received their first approvals, first marketing applications for three mAbs (vedolizumab, ramucirumab, obinutuzumab) were submitted to regulatory agencies, and five mAbs (brodalumab, MABp1, moxetumomab pasudotox, tildrakizumab, rilotumumab) entered their first Phase 3 studies. The current total of commercially-sponsored antibody therapeutics undergoing evaluation in late-stage studies is 30. Recently announced study results for farletuzumab, naptumomab estafenatox, and tabalumab indicate that clinical endpoints were not met in some Phase 3 studies of these product candidates.

  18. China to Regulate Natural Gas Import from Mid-Year

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ The Chinese government plans to introduce new measures on June 10 to regulate imports of natural gas in order to protect its three major gas importers from intense domestic competition. The Ministry of Commerce said late-May that the move would end the chaotic competition between China's big-three oil and gas companies - China National Petroleum Corporation (CNPC), China Petrochemical Corporation (Sinopec) and China National Offshore Oil Corporation (CNOOC) - in the purchase of gas,which has helped overseas exporters raise prices. The competition has been blamed on the lax import system for natural gas that is currently in place. Enterprises, at present, do not have to satisfy any conditions to obtain import permits for natural gas. After June 10, each application for an import permit will be examined and approved.

  19. Pacific Northwest National Laboratory FY1996 midyear self-evaluation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    As stated in our mission, the Laboratory is concentrated on DOE`s environmental quality mission and the scientific research required to support that mission. The Laboratory also supports the energy resources and national security missions in areas where an overlap between our core competencies and DOE`s goals exists. Our intent for fiscal year l996 is to focus our efforts on the critical outcomes necessary for us to meet DOE`s needs. Six Critical Outcomes were established and substantial progress has been made against five of those outcomes during the first half of the fiscal year. A summary of progress and key issues is provided. The Critical Outcomes are: Environmental Molecular Sciences Laboratory; Environmental Management; Scientific Excellence and Productivity; ES&H/Conduct of Operations; Leadership; and Economic Development. The Laboratory has also made a significant commitment to the implementation of a fully integrated self-assessment program. Efforts during the first half of the fiscal year have been focused on developing an approach for the overall program and implementation in selected organizations. The approach is holistic and focuses assessment on activities important to the successful completion of our critical outcomes. Progress towards full implementation of the integrated assessment program is meeting expectations in general, but significant effort still needs to be applied to obtain effective implementation across the Laboratory and to ensure integration with the business planning process.

  20. 2013 Annual Conference on Experimental and Applied Mechanics

    CERN Document Server

    Casem, Dan; Kimberley, Jamie; Barthelat, François; Zavattieri, Pablo; Antoun, Bonnie; Qi, H; Hall, Richard; Tandon, G; Lu, Hongbing; Lu, Charles; Furmanski, Jevan; Amirkhizi, Alireza; Korach, Chad; Prorok, Barton; Grande-Allen, K; III, Gordon; Prorok, Barton; Starman, LaVern; Furlong, Cosme; Tandon, G; Tekalur, Srinivasan; Ralph, Carter; Sottos, Nancy; Blaiszik, Benjamin; Jay, Carroll; Rossi, Marco; Sasso, Marco; Connesson, Nathanael; Singh, Raman; DeWald, Adrian; Backman, David; Gloeckner, Paul; Jin, Helena; Sciammarella, Cesar; Yoshida, Sanichiro; Lamberti, Luciano; Vol.1 Dynamic Behavior of Materials; Vol.2 Challenges In Mechanics of Time-Dependent Materials and Processes in Conventional and Multifunctional Materials; Vol.3 Advancement of Optical Methods in Experimental Mechanics; Vol.4 Mechanics of Biological Systems and Materials; Vol.5 MEMS and Nanotechnology; Vol.6 Experimental Mechanics of Composite, Hybrid, and Multifunctional Materials; Vol.7 Fracture and Fatigue; Vol.8 Residual Stress, Thermomechanics & Infrared Imaging, Hybrid Techniques and Inverse Problems; SEM 2013

    2014-01-01

    This critical collection examines a range of topics in fracture and fatigue, including environmental and loading effects in fracture and fatigue and DIC and fracture, as presented in early findings and case studies from the Proceedings of the 2013 Annual Conference on Experimental and Applied Mechanics. The collection includes papers in the following general technical research areas: • Microstructural Effects in Fatigue & Fracture • Fracture of Interfaces • Fracture of Composites and Interface Cracks • Fatigue & Fracture: Environmental & Loading Eff ects • Fracture & Digital Image Correlation Fracture and Fatigue

  1. CSIR: Mining Technology annual review 1996/97

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    CSIR: Mining Technology works in close collaboration and strategic partnership with the mining industry, government institutions and employee organizations by acquiring, developing and transferring technologies to improve the safety and health of their employees, and to improve the profitability of the mining industry. The annual report describes achievements over the year in the areas of: rock engineering (including rockburst control, mine layout, stope and gully support, coal mining); environmental safety and health on topics such as occupational hygiene services, methane explosions, blasting techniques; and mining systems (orebody information, hydraulic transport mine mechanization, engineering design and automation, mine services). A list of Mining Technology`s 1996/97 publications is given.

  2. Rosacea-like eruption due to topical pimecrolimus.

    Science.gov (United States)

    El-Heis, S; Buckley, D A

    2015-05-18

    Topical calcineurin inhibitors have been used outside their approved indications for a number of conditions, including topical steroid-induced rosacea. However, tacrolimus ointment itself has been reported to trigger rosacea in a small number of cases. We report a case of a rosacea-like eruption in a 39-year-old woman occurring after the use of pimecrolimus cream for 12 months for atopic dermatitis. Withdrawal of pimecrolimus combined with treatment with oral lymecycline, topical metronidazole, and an emollient resulted in resolution of the eruption. There have been 5 previously reported cases of a topical pimecrolimus-induced rosacea-like eruption suggesting that this rare side-effect may be a class effect of all topical calcineurin inhibitors. Dermatologists prescribing these drugs should be aware of this uncommon complication and may wish to warn patients of its occurrence as a potential side-effect when using topical calcineurin inhibitors in facial skin in adults.

  3. Approach to extracting hot topics based on network traffic content

    Institute of Scientific and Technical Information of China (English)

    Yadong ZHOU; Xiaohong GUAN; Qindong SUN; Wei LI; Jing TAO

    2009-01-01

    This article presents the formal definition and description of popular topics on the Internet,analyzes the relationship between popular words and topics,and finally introduces a method that uses statistics and correlation of the popular words in traffic content and network flow characteristics as input for extracting popular topics on the Internet.Based on this,this article adapts a clustering algorithm to extract popular topics and gives formalized results.The test results show that this method has an accuracy of 16.7% in extracting popular topics on the Internet.Compared with web mining and topic detection and tracking (TDT),it can provide a more suitable data source for effective recovery of Internet public opinions.

  4. TMBP: A Topic Modeling Toolbox Using Belief Propagation

    CERN Document Server

    Zeng, Jia

    2012-01-01

    Latent Dirichlet allocation (LDA) is an important class of hierarchical Bayesian models for probabilistic topic modeling, which attracts worldwide interests and touches on many important applications in text mining, computer vision and computational biology. This paper introduces a topic modeling toolbox (TMBP) based on the belief propagation (BP) algorithms. This toolbox is implemented by MEX C++/MATLAB platform for either Windows or Linux. The current version includes various learning algorithms for latent Dirichlet allocation (LDA), author-topic models (ATM), relational topic models (RTM), and labeled LDA (LaLDA). This toolbox is an ongoing project and more and more BP-based learning algorithms for various LDA-based topic models will be added in the near future. Interested readers may also extend this toolbox for solving more complicated topic modeling problems. The source code is freely available under the GNU General Public Licence, Version 1.0 at http://code.google.com/p/tmbp-topicmodel-beliefpropagatio...

  5. Topic- and Time-Oriented Visual Text Analysis.

    Science.gov (United States)

    Dou, Wenwen; Liu, Shixia

    2016-01-01

    To facilitate the process of converting textual data into actionable knowledge, visual text analysis has become a popular topic with active research efforts contributed by researchers worldwide. Here the authors present the benefits of combing text analysis (topic models in particular) with interactive visualization. They then highlight examples from prior work on topic- and time-oriented visual text analysis and discuss challenges that warrant additional future research.

  6. Topical fluoride as a cause of dental fluorosis in children

    OpenAIRE

    Wong, MCM; Lo, ECM; Glenny, AM; Tsang, BWK; Worthington, HV; Marinho, VCC

    2009-01-01

    BACKGROUND: For many years, topical use of fluorides has gained greater popularity than systemic use of fluorides. A possible adverse effect associated with the use of topical fluoride is the development of dental fluorosis due to the ingestion of excessive fluoride by young children with developing teeth. OBJECTIVES: To describe the relationship between the use of topical fluorides in young children and the risk of developing dental fluorosis. SEARCH STRATEGY: Electronic search of the Cochra...

  7. RUC at TREC 2014: Select Resources Using Topic Models

    Science.gov (United States)

    2014-11-01

    them being observed (i.e. sampled). To infer the topic Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for the...Selection. In CIKM 2009, pages 1277-1286. [10] M. Baillie, M. Carmen, and F. Crestani. A Multiple- Collection Latent Topic Model for Federated...RUC at TREC 2014: Select Resources Using Topic Models Qiuyue Wang, Shaochen Shi, Wei Cao School of Information Renmin University of China Beijing

  8. Topic Map: An Ontology Framework for Information Retrieval

    CERN Document Server

    Kannan, Rajkumar

    2010-01-01

    The basic classification techniques for organizing information are thesauri, taxonomy and faceted classification. Topic map is relatively a new entrant to this information space. Topic map standard describes how complex relationships between abstract concepts and real world resources can be represented using XML syntax. This paper explores how topic map incorporates the traditional techniques and what are its advantages and disadvantages in several dimensions such as content management, indexing, knowledge representation, constraint specification and query languages in the context of information retrieval. The constructs of topic maps are illustrated with a use-case implemented in XTM

  9. topicmodels: An R Package for Fitting Topic Models

    Directory of Open Access Journals (Sweden)

    Bettina Grun

    2011-05-01

    Full Text Available Topic models allow the probabilistic modeling of term frequency occurrences in documents. The fitted model can be used to estimate the similarity between documents as well as between a set of specified keywords using an additional layer of latent variables which are referred to as topics. The R package topicmodels provides basic infrastructure for fitting topic models based on data structures from the text mining package tm. The package includes interfaces to two algorithms for fitting topic models: the variational expectation-maximization algorithm provided by David M. Blei and co-authors and an algorithm using Gibbs sampling by Xuan-Hieu Phan and co-authors.

  10. Topics in linear optical quantum computation

    Science.gov (United States)

    Glancy, Scott Charles

    This thesis covers several topics in optical quantum computation. A quantum computer is a computational device which is able to manipulate information by performing unitary operations on some physical system whose state can be described as a vector (or mixture of vectors) in a Hilbert space. The basic unit of information, called the qubit, is considered to be a system with two orthogonal states, which are assigned logical values of 0 and 1. Photons make excellent candidates to serve as qubits. They have little interactions with the environment. Many operations can be performed using very simple linear optical devices such as beam splitters and phase shifters. Photons can easily be processed through circuit-like networks. Operations can be performed in very short times. Photons are ideally suited for the long-distance communication of quantum information. The great difficulty in constructing an optical quantum computer is that photons naturally interact weakly with one another. This thesis first gives a brief review of two early approaches to optical quantum computation. It will describe how any discrete unitary operation can be performed using a single photon and a network of beam splitters, and how the Kerr effect can be used to construct a two photon logic gate. Second, this work provides a thorough introduction to the linear optical quantum computer developed by Knill, Laflamme, and Milburn. It then presents this author's results on the reliability of this scheme when implemented using imperfect photon detectors. This author finds that quantum computers of this sort cannot be built using current technology. Third, this dissertation describes a method for constructing a linear optical quantum computer using nearly orthogonal coherent states of light as the qubits. It shows how a universal set of logic operations can be performed, including calculations of the fidelity with which these operations may be accomplished. It discusses methods for reducing and

  11. 2014 HPC Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Jennings, Barbara [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2014-10-01

    Our commitment is to support you through delivery of an IT environment that provides mission value by transforming the way you use, protect, and access information. We approach this through technical innovation, risk management, and relationships with our workforce, Laboratories leadership, and policy makers nationwide. This second edition of our HPC Annual Report continues our commitment to communicate the details and impact of Sandia’s large-scale computing resources that support the programs associated with our diverse mission areas. A key tenet to our approach is to work with our mission partners to understand and anticipate their requirements and formulate an investment strategy that is aligned with those Laboratories priorities. In doing this, our investments include not only expanding the resources available for scientific computing and modeling and simulation, but also acquiring large-scale systems for data analytics, cloud computing, and Emulytics. We are also investigating new computer architectures in our advanced systems test bed to guide future platform designs and prepare for changes in our code development models. Our initial investments in large-scale institutional platforms that are optimized for Informatics and Emulytics work are serving a diverse customer base. We anticipate continued growth and expansion of these resources in the coming years as the use of these analytic techniques expands across our mission space. If your program could benefit from an investment in innovative systems, please work through your Program Management Unit ’s Mission Computing Council representatives to engage our teams.

  12. ANNUAL INTERVIEWS (MAPS)

    CERN Multimedia

    Human Resources Division

    2002-01-01

    The calendar for the 2002/2003 annual interview programme is confirmed as normally from 15 November 2002 to 15 February 2002 as foreseen in Administrative Circular N° 26 (rev. 2). However, where it is preferred to be as close as possible to 12 months since the last interview, supervisors and staff concerned may agree to the interview taking place up to 15 March 2003. This may also be necessary due to the roles of different supervisors resulting from the particular situations of divisional re-restructurings and detachments this year. The report form template is as last year available on the HR Division Website. A banner on the internal homepage leads directly to the page with the form. In collaboration with AS Division, the MAPS form including the personal data for the first page can be generated via the Human Resources Toolkit (HRT) application. For this exercise each staff member can now generate his/her own MAPS form. Information about how to do this is available here. Human Resources Division Tel. ...

  13. 2007 LDRD ANNUAL REPORT

    Energy Technology Data Exchange (ETDEWEB)

    French, T

    2008-12-16

    I am pleased to present the fiscal year 2007 Laboratory Directed Research and Development (LDRD) annual report. This represents the first year that SRNL has been eligible for LDRD participation and our results to date demonstrate we are off to an excellent start. SRNL became a National Laboratory in 2004, and was designated the 'Corporate Laboratory' for the DOE Office of Environmental Management (EM) in 2006. As you will see, we have made great progress since these designations. The LDRD program is one of the tools SRNL is using to enable achievement of our strategic goals for the DOE. The LDRD program allows the laboratory to blend a strong basic science component into our applied technical portfolio. This blending of science with applied technology provides opportunities for our scientists to strengthen our capabilities and delivery. The LDRD program is vital to help SRNL attract and retain leading scientists and engineers who will help build SRNL's future and achieve DOE mission objectives. This program has stimulated our research staff creativity, while realizing benefits from their participation. This investment will yield long term dividends to the DOE in its Environmental Management, Energy, and National Security missions.

  14. Annual Energy Review 2000

    Energy Technology Data Exchange (ETDEWEB)

    Seiferlein, Katherine E. [USDOE Energy Information Administration (EIA), Washington, DC (United States)

    2001-08-01

    The Annual Energy Review (AER) presents the Energy Information Administration’s historical energy statistics. For many series, statistics are given for every year from 1949 through 2000. The statistics, expressed in either physical units or British thermal units, cover all major energy activities, including consumption, production, trade, stocks, and prices, for all major energy commodities, including fossil fuels, electricity, and renewable energy sources. Publication of this report is required under Public Law 95–91 (Department of Energy Organization Act), Section 205(c), and is in keeping with responsibilities given to the Energy Information Administration under Section 205(a)(2), which states: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....” The AER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. EIA welcomes suggestions from readers regarding data series in the AER and in other EIA publications.

  15. Annual Energy Review 2002

    Energy Technology Data Exchange (ETDEWEB)

    Seiferlein, Katherine E. [USDOE Energy Information Administration (EIA), Washington, DC (United States)

    2003-10-01

    The Annual Energy Review (AER) presents the Energy Information Administration’s historical energy statistics. For many series, statistics are given for every year from 1949 through 2002. The statistics, expressed in either physical units or British thermal units, cover all major energy activities, including consumption, production, trade, stocks, and prices, for all major energy commodities, including fossil fuels, electricity, and renewable energy sources. Publication of this report is required under Public Law 95–91 (Department of Energy Organization Act), Section 205(c), and is in keeping with responsibilities given to the Energy Information Administration (EIA) under Section 205(a)(2), which states: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....” The AER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. EIA welcomes suggestions from readers regarding data series in the AER and in other EIA publications. Related Publication: Readers of the AER may also be interested in EIA’s Monthly Energy Review, which presents monthly updates of many of the data in the AER. Contact our National Energy Information Center for more information.

  16. Annual Energy Review 1997

    Energy Technology Data Exchange (ETDEWEB)

    Seiferlein, Katherine E. [USDOE Energy Information Administration (EIA), Washington, DC (United States)

    1998-07-01

    The Annual Energy Review (AER) presents the Energy Information Administration’s historical energy statistics. For many series, statistics are given for every year from 1949 through 1997. The statistics, expressed in either physical units or British thermal units, cover all major energy activities, including consumption, production, trade, stocks, and prices, for all major energy commodities, including fossil fuels, electricity, and renewable energy sources. Publication of this report is in keeping with responsibilities given to the Energy Information Administration (EIA) in Public Law 95–91 (Department of Energy Organization Act), which states, in part, in Section 205(a)(2) that: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....” The AER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. EIA welcomes suggestions from readers regarding data series in the AER and in other EIA publications.

  17. SKB Annual Report 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-05-01

    This is the annual report of the Swedish Nuclear Fuel and Waste Management Co (SKB). Part 1 of the report contains an overview of the SKB activities in different fields, and part 2 gives a description of the research and development work on nuclear waste disposal performed during 1996. Lectures and publications as well as reports issued during 1996 are listed in part 3, and summaries of the reports are listed in part 4. The task of SKB is to transport, store and dispose of the spent nuclear fuel and radioactive wastes from the nuclear power plants and to perform the research and development and other measures necessary for this work. SKB is the owner of CLAB, the Central Interim Storage Facility for spent fuel, located at Oskarshamn. CLAB was taken into operation in July 1985 and by the end of 1996 about 2500 tons of spent fuel have been received. At Forsmark the Final Repository for Radioactive Operational Waste (SFR) was taken into operation in April 1988. The repository is situated in crystalline rock under the Baltic Sea. SFR has currently a capacity of about 60000 m{sup 3} or waste. At the end of 1996 at total of 21000 m{sup 3} of waste has been deposited. Transportation from the reactor sites to CLAB and SFR is made by a specially designed ship, M/S Sigyn. The total cost for R,D and D during 1996 amounted to 124 MSEK (about 15 MUSD).

  18. NAGRA annual report 2012

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-07-01

    This report issued by the Swiss National Co-operative for the Disposal of Radioactive Waste NAGRA reviews the co-operative’s activities in the year 2012. In January 2012, the Swiss Federal Office of Energy (SFOE) announced the 20 proposals made by NAGRA for siting areas for nuclear waste repository surface facilities. The discussions within the framework of regional participation focused on the location and layout of the surface facility within the defined planning perimeter. Progress in NAGRA’s work on the safety-based comparison and further narrowing-down of the geological siting regions for the repositories is reported on. NAGRA’s mandate includes its responsibility for preparing the technical and scientific basis for the safe, long-term management of nuclear waste. Progress on the so-called ‘Sectorial Plan’ which addresses the fundamental question of how to safely dispose of all types of radioactive waste is reported on, as is the process of defining locations in Switzerland for one or more deep repositories for nuclear wastes. Public participation in the process is reported on and geochemical considerations involved in designing the repositories are looked at. The work done in the rock laboratories is summarised and international co-operation is noted. The NAGRA ‘Time Ride’ exhibition is also briefly looked at. The report is completed with listings of those involved in NAGRA’s Board of Directors, commissions and auditors along with the annual financial statement for 2012.

  19. Annual report 1997

    Energy Technology Data Exchange (ETDEWEB)

    Chmielewska, D.; Infeld, E.; Zupranski, P. [eds.

    1998-12-31

    In the presented ``Annual Report 1997`` the scientific, organizational end educational activities of the Andrzej Soltan Institute for Nuclear Studies (SINS) are presented. The document is divided into two parts. First of them consist of the general information about management, scientific council, department of SINS, scientific staff, visiting scientists, list of research project (grants), PhD and DSc theses as well as the information about organized schools and exhibitions. The second one: ``Reports on Research`` describes the research activities of SINS. It is divided into 12 parts - in which the works of SINS departments and establishments are presented (Department of Nuclear Reactions, Department of Nuclear Spectroscopy and Technique, Department of Nuclear Electronics, Department of Radiation Shielding and Dosimetry, Department of Plasma Physics and Technology, Department of High Energy Physics, Department of Cosmic Radiation Physics, Department of Atomic Nucleus Theory, Department of Radiation Detectors, Department of Accelerator Physics and Technology, Department of Training an Consulting and Establishment for Nuclear Equipment). Each of these parts are foreworded by short overview given by the head of appropriate department. The foreword, in which the whole activities of the SINS are summarized, given by head of the Institute professor Z. Sujkowski is also given

  20. Annual Report 1998

    Energy Technology Data Exchange (ETDEWEB)

    Chmielewska, D.; Infeld, E.; Preibisz, Z.; Zupranski, P. [eds.

    1999-10-01

    In the presented ``Annual Report 1998`` the scientific, organizational and educational activities of the Andrzej Soltan Institute for Nuclear Studies (SINS) are presented. The document is divided into two parts. First of them consists of the general information about management, scientific council, department of SINS, scientific staff, visiting scientists, list of research project (grants), PhD and DSc theses as well as the information about organized schools and exhibitions. The second one: ``Reports on Research`` describes the research activities of SINS. It is divided into 12 parts - in which the works of SINS departments and establishments are presented (Department of Nuclear Reactions, Department of Nuclear Spectroscopy and Technique, Department of Nuclear Electronics, Department of Radiation Shielding and Dosimetry, Department of Plasma Physics and Technology, Department of High Energy Physics, Department of Cosmic Radiation Physics, Department of Nuclear Theory, Department of Radiation Detectors, Department of Accelerator Physics and Technology, Department of Training an Consulting and Establishment for Nuclear Equipment). Each of these parts are preceded by a short overview given by the head of the given department. The foreword, in which the whole activities of the SINS are summarized, given by head of the Institute professor Z. Sujkowski is also given

  1. ILL Annual report 97

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    In 1997 the reactor operated for the planned 225 days and more than 750 experiments were carried out. Among the experimental highlights are 2 contrasting examples of the new types of experiments now possible using the new high-intensity diffractometer D2O: stroboscopic measurements of kinetic processes and rapid texture measurements of structural materials. Some early results from the new high-resolution gamma spectrometer in the study of nuclear structure are also presented. Another new facility is just coming into service: the 2{pi} image-plate detector LADI, optimised for Laue measurements on biological crystals. The contrast between biological experiments and for example those on superconductivity or neutron {beta}-decay, illustrates very well the range of scientific questions addressed through the use of ILL`s neutron beams. 30 brief accounts of research work achieved during this year are given, they are classified under 9 topics: polymers and colloids, chemistry and structure, biology, materials science, liquids and glasses, magnetism, strongly correlated electron systems, quantum systems, nuclear and fundamental physics. The scheduled new developments are described and a list of the publications is also given

  2. 2013 NASA Range Safety Annual Report

    Science.gov (United States)

    Dumont, Alan G.

    2013-01-01

    Welcome to the 2013 edition of the NASA Range Safety Annual Report. Funded by NASA Headquarters, this report provides an Agency overview for current and potential range users. This report contains articles which cover a variety of subject areas, summaries of various activities performed during the past year, links to past reports, and information on several projects that may have a profound impact on the way business will be conducted in the future. Specific topics discussed in the 2013 NASA Range Safety Annual Report include a program overview and 2013 highlights, Range Safety Training, Independent Assessments, support to Program Operations at all ranges conducting NASA launch/flight operations, a continuing overview of emerging range safety-related technologies, and status reports from all of the NASA Centers that have Range Safety responsibilities. Every effort has been made to include the most current information available. We recommend this report be used only for guidance and that the validity and accuracy of all articles be verified for updates. As is the case each year, we had a wide variety of contributors to this report from across our NASA Centers and the national range safety community at large, and I wish to thank them all. On a sad note, we lost one of our close colleagues, Dr. Jim Simpson, due to his sudden passing in December. His work advancing the envelope of autonomous flight safety systems software/hardware development leaves a lasting impression on our community. Such systems are being flight tested today and may one day be considered routine in the range safety business. The NASA family has lost a pioneer in our field, and he will surely be missed. In conclusion, it has been a very busy and productive year, and I look forward to working with all of you in NASA Centers/Programs/Projects and with the national Range Safety community in making Flight/Space activities as safe as they can be in the upcoming year.

  3. LLNL NESHAPs 2004 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Harrach, R; Gallegos, G; Peterson, R; Wilson, K; Harrach, R J; Gallegos, G M; Peterson, S R; Wilson, K R

    2005-06-27

    This annual report is prepared pursuant to the National Emission Standards for Hazardous Air Pollutants (NESHAPs; Title 40 Code of Federal Regulations [CFR] Part 61, Subpart H). Subpart H governs radionuclide emissions to air from Department of Energy (DOE) facilities.

  4. Nursing Facility Initiative Annual Report

    Data.gov (United States)

    U.S. Department of Health & Human Services — This annual report summarizes impacts from the Initiative to Reduce Avoidable Hospitalizations among Nursing Facility Residents in 2014. This initiative is designed...

  5. 2005 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Chrzanowski, P; Walter, K

    2006-03-31

    As the cover of our ''2005 Annual Report'' highlights, Lawrence Livermore National Laboratory joined the international science community in celebrating the World Year of Physics in 2005, with special events and science outreach and education programs. Einstein's remarkable discoveries in 1905 provided an opportunity to reflect on how physics has changed the world during the last century and on the promise of future beneficial discoveries. For half of the past century, Lawrence Livermore, which was established to meet an urgent national security need, has been contributing to the advancement of science and technology in a very special way. Co-founder Ernest O. Lawrence was the leading proponent in his generation of large-scale, multidisciplinary science and technology teams. That's Livermore's distinctive heritage and our continuing approach as a national laboratory managed and operated by the University of California for the Department of Energy's National Nuclear Security Administration (DOE/NNSA). We focus on important problems that affect our nation's security and seek breakthrough advances in science and technology to achieve mission goals. An event in 2005 exemplifies our focus on science and technology advances in support of mission goals. In October, distinguished visitors came to Livermore to celebrate the tenth anniversary of the Accelerated Strategic Computing Initiative (now called the Advanced Simulation and Computing Program, or ASC). ASC was launched in 1995 by DOE/NNSA to achieve a million-fold increase in computing power in a decade. The goal was motivated by the need to simulate the three-dimensional performance of a nuclear weapon in sufficient resolution and with the appropriately detailed physics models included. This mission-driven goal is a key part of fulfilling Livermore's foremost responsibility to ensure that the nuclear weapons in the nation's smaller 21st-century stockpile remain

  6. Annual energy review 2003

    Energy Technology Data Exchange (ETDEWEB)

    Seiferlein, Katherin E. [Energy Information Adminstration (EIA), Washington, DC (United States)

    2004-09-30

    The Annual Energy Review 2003 is a statistical history of energy activities in the United States in modern times. Data are presented for all major forms of energy by production (extraction of energy from the earth, water, and other parts of the environment), consumption by end-user sector, trade with other nations, storage changes, and pricing. Much of the data provided covers the fossil fuels—coal, petroleum, and natural gas. Fossil fuels are nature’s batteries; they have stored the sun’s energy over millennia past. It is primarily that captured energy that we are drawing on today to fuel the activities of the modern economy. Data in this report measure the extraordinary expansion of our use of fossil fuels from 29 quadrillion British thermal units (Btu) in 1949 to 84 quadrillion Btu in 2003. In recent years, fossil fuels accounted for 86 percent of all energy consumed in the United States. This report also records the development of an entirely new energy industry—the nuclear electric power industry. The industry got its start in this country in 1957 when the Shippingport, Pennsylvania, nuclear electric power plant came on line. Since that time, the industry has grown to account for 20 percent of our electrical output and 8 percent of all energy used in the country. Renewable energy is a third major category of energy reported in this volume. Unlike fossil fuels, which are finite in supply, renewable energy is essentially inexhaustible because it can be replenished. Types of energy covered in the renewable category include conventional hydroelectric power, which is power derived from falling water; wood; waste; alcohol fuels; geothermal; solar; and wind. Together, these forms of energy accounted for about 6 percent of all U.S. energy consumption in recent years.

  7. Annual energy review 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-07-01

    The Annual Energy Review (AER) is a historical data report that tells many stories. It describes, in numbers, the changes that have occurred in US energy markets since the midpoint of the 20th century. In many cases, those markets differ vastly from those of a half-century ago. By studying the graphs and data tables presented in this report, readers can learn about past energy supply and usage in the United States and gain an understanding of the issues in energy and the environment now before use. While most of this year`s report content is similar to last year`s, there are some noteworthy developments. Table 1.1 has been restructured into more summarized groupings -- fossil fuels, nuclear electric power, and renewable energy -- to aid analysts in their examination of the basic trends in those broad categories. Readers` attention is also directed to the electricity section, where considerable reformatting of the tables and graphs has been carried out to help clarify past and recent trends in the electric power industry as it enters a period of radical restructuring. Table 9.1, which summarizes US nuclear generating units, has been redeveloped to cover the entire history of the industry in this country and to provide categories relevant in assessing the future of the industry, such as the numbers of ordered generating units that have been canceled and those that were built and later shut down. In general, the AER emphasizes domestic energy statistics. Sections 1 through 10 and Section 12 are devoted mostly to US data; Section 11 reports on international statistics and world totals. 140 figs., 141 tabs.

  8. Annual Report, 1998

    Energy Technology Data Exchange (ETDEWEB)

    Buettner, Herma G.; Leadbetter, Alan J. [eds.] [Institut Max von Laue - Paul Langevin (ILL), 38 - Grenoble (France)

    1999-11-01

    In this Annual Report a selection of about 30 scientific achievements are highlighted. These are intended to represent the huge range of high quality research carried out at ILL. In 1998 about 750 experiments were performed in the 225 days of reactor operation. The fields of magnetism and strongly correlated electron systems continue to be fertile and to throw up strong new growth. Remarkable new advances are coming from the applications of both existing and new neutron techniques and the development of new materials. These highlights concern superconductors, nano-magnetic particles, colossal magneto-resistance, magnetic-nuclear correlations, quantum spin systems and more. Novel magnetic measurements are also reported for a quasicrystal and on thin films of both normal and superconducting materials. Thanks to special abilities of neutrons to penetrate matter new results were obtained: following the production of novel intermetallic compounds, pressure dependence of phonon frequencies, the structure of glasses, solutions (in both bulk and thin films) and adsorbed phases; dynamics and relaxation in liquids; the confirmation of reptant motion in linear polymers, self-assembly and shear phenomena in liquid crystals. Three important results from nuclear physics are also included. These involve: fission-produced neutron-rich nuclei, weighing gamma photons in connection with the determination of fundamental constants and the determination of interatomic potentials from the slowing down process of atoms recoiling from gamma-ray emission - a direct link between nuclear and solid-state physics. The neutron experiments of importance for particle physics and biology will be reported next year

  9. Microblog Hot Spot Mining Based on PAM Probabilistic Topic Model

    Directory of Open Access Journals (Sweden)

    Zheng Yaxin

    2015-01-01

    Full Text Available Microblogs are short texts carried with limited information, which will increase the difficulty of topic mining. This paper proposes the use of PAM (Pachinko Allocation Model probabilistic topic model to extract the generative model of text’s implicit theme for microblog hot spot mining. First, three categories of microblog and the main contribution of this paper are illustrated. Second, for there are four topic models which are respectively explained, the PAM model is introduced in detail in terms of how to generate a document, the accuracy of document classification and the topic correlation in PAM. Finally, MapReduce is described. For the number of microblogs is huge as well as the number of contactors, the totally number of words is relatively small. With MapReduce, microblogs data are split by contactor, document-topic count matrix and contactor-topic count matrix can be locally stored while the word-topic count matrix must be globally stored. Thus, the hot spot mining can be achieved on the basis of PAM probabilistic topic model.

  10. Topical macrolide immunomodulators: a role in the treatment of vitiligo?

    NARCIS (Netherlands)

    Tjioe, M.; Vissers, W.H.P.M.; Gerritsen, M.J.P.

    2006-01-01

    Recently, topical macrolide immunomodulators have been successfully introduced in the treatment of atopic dermatitis. With the growing interest in this new line of topical immunosuppressants, research into the efficacy of these medicines in other T-cell-mediated skin diseases, such as psoriasis, lic

  11. Topic Sequence and Emphasis Variability of Selected Organic Chemistry Textbooks

    Science.gov (United States)

    Houseknecht, Justin B.

    2010-01-01

    Textbook choice has a significant effect upon course success. Among the factors that influence this decision, two of the most important are material organization and emphasis. This paper examines the sequencing of 19 organic chemistry topics, 21 concepts and skills, and 7 biological topics within nine of the currently available organic textbooks.…

  12. Improving Calculus II and III through the Redistribution of Topics

    Science.gov (United States)

    George, C. Yousuf; Koetz, Matt; Lewis, Heather A.

    2016-01-01

    Three years ago our mathematics department rearranged the topics in second and third semester calculus, moving multivariable calculus to the second semester and series to the third semester. This paper describes the new arrangement of topics, and how it could be adapted to calculus curricula at different schools. It also explains the benefits we…

  13. Frequent Errors in Chinese EFL Learners' Topic-Based Writings

    Science.gov (United States)

    Zhan, Huifang

    2015-01-01

    This paper investigated a large number of errors found in the topic-based writings of Chinese EFL learners, especially provided an analysis on frequent errors, to find useful pedagogical implications for English grammar teaching and writing instruction in Chinese EFL setting. Students' topic-based writings were examined by the author. The findings…

  14. Comparison of topical tretinoin and betamethasone in oral lichen planus

    Directory of Open Access Journals (Sweden)

    Kar H

    1996-01-01

    Full Text Available Thirty-one patients of oral lichen planus were enrolled in this study and two groups were made. Group 1 consisting of 16 patients who applied topical tretinoin 0.05% and Group 2 comprising of 15 patients who were given topical betamethasone dipropionate 0.05%. The patients applying tretinoin showed statistically significant improvement as compared to patients applying betamethasone.

  15. 1st meeting on topical drug delivery to the nail.

    Science.gov (United States)

    Murdan, Sudaxshina

    2007-07-01

    The first ever symposium dedicated solely to drug delivery to the nail following topical application was held on the 2nd April 2007, in London, UK, organised by Dr Clive Roper (Charles River Laboratories, Scotland) and Dr Sudaxshina Murdan (School of Pharmacy, University of London, UK), under the auspices of Skin Forum. The 1-day meeting was attended by approximately 35 delegates from industry, academia and hospitals, and provided a much-needed forum for the presentation and discussion of research and problems in this emerging field. Topical drug delivery is especially suitable for onychomycosis (fungal infections of the nail plate and/or nail bed) and nail psoriasis, which affect 2 - 13 and 1 - 3% of the general population, respectively, and make up the bulk of nail disorders. Topical therapy would avoid the adverse events and drug interactions of systemic antifungal agents and the pain of injection when antipsoriatic agents are injected into affected nail folds. However, successful topical therapy is extremely challenging due to the very low permeability of the nail plate. Five speakers spoke about various aspects of topical drug delivery to the nail, including review of the nail plate structure, function, diseases, their existing therapies (systemic and topical), limitations and global sales. The need for effective topical drug delivery to the nail to overcome the problems associated with present treatment, and the fact that there are few topical formulations available for the treatment of nail fungal infections and psoriasis, and the even fewer effective formulations, was highlighted.

  16. Orienting to Topic in Clinical Discourse Elicitation of Everyday Conversation

    Science.gov (United States)

    Fond, Marissa Joanne

    2013-01-01

    Talking topically, as it is understood intuitively and evoked metadiscursively, requires constructing an intersubjective orientation to talk that must be continually renewed. Analysis of interactants' ability to orient to topic emergence provides evidence of what is achieved in interaction, as well as why conversational coordination can lapse…

  17. March Madness! A Look at Evergreen Parenting Topics

    Science.gov (United States)

    Parenting for High Potential, 2014

    2014-01-01

    Many topics in the world of gifted are evergreen. Whether it be 1964 or 2014, they're still relevant. In this issue, "Parenting for High Potential" takes a peek into the archives to look at topics that have run in various March issues of PHP through the years. No matter where you are on the gifted journey, there's something here for…

  18. Immigration, Cultural-Linguistic Diversity, and Topics in Language Disorders

    Science.gov (United States)

    Cheng, Li-Rong Lilly

    2010-01-01

    This article summarizes 4 topics contributed by the author over the last 30 years of "Topics in Language Disorders" that address the issues of immigration, migration, and refugees. The focus is on the historical perspectives on evolution of terminologies from limited English proficient to English language learner and English as a new language.…

  19. An update on topical therapies for mild-moderate psoriasis

    NARCIS (Netherlands)

    Kerkhof, P.C.M. van de

    2015-01-01

    Topical therapies are the mainstream treatment of psoriasis because most patients have mild disease. First-line treatments are vitamin D derivatives and corticosteroids. These treatments are usually given in combination schedules. For topical treatments the selection of the most appropriate vehicle

  20. Topics in Finance Part VI--Capital Budgeting

    Science.gov (United States)

    Laux, Judy

    2011-01-01

    This series on the theory of financial management offers insight into the roles of stockholder wealth maximization, the risk-return tradeoff, and agency conflicts as they apply to major topics in finance. The current article investigates capital budgeting. Much literature addresses this topic, with a number of articles challenging mainstream…

  1. Laser Program annual report 1987

    Energy Technology Data Exchange (ETDEWEB)

    O' Neal, E.M.; Murphy, P.W.; Canada, J.A.; Kirvel, R.D.; Peck, T.; Price, M.E.; Prono, J.K.; Reid, S.G.; Wallerstein, L.; Wright, T.W. (eds.)

    1989-07-01

    This report discusses the following topics: target design and experiments; target materials development; laboratory x-ray lasers; laser science and technology; high-average-power solid state lasers; and ICF applications studies.

  2. Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy

    Directory of Open Access Journals (Sweden)

    Alexander L. Pan

    2012-01-01

    Full Text Available Spontaneous coronary artery dissection is a rare condition, usually presenting as an acute coronary syndrome, and is often seen in states associated with high systemic estrogen levels such as pregnancy or oral contraceptive use. While topical hormonal replacement therapy may result in increased estrogen levels similar to those documented with oral contraceptive use, there are no reported cases of spontaneous coronary dissection with topical hormonal replacement therapy. We describe a 53-year-old female who developed two spontaneous coronary dissections while on topical hormonal replacement therapy. The patient had no other risk factors for coronary dissection. After withdrawal from topical hormonal therapy, our patient has done well and has not had recurrent coronary artery dissections over a one-year follow-up period. The potential contributory role of topical hormonal therapy as a cause of spontaneous coronary dissection should be recognized.

  3. A TEXT MINING RESEARCH BASED ON LDA TOPIC MODELLING

    Directory of Open Access Journals (Sweden)

    Zhou Tong

    2016-05-01

    Full Text Available A Large number of digital text information is generated every day. Effectively searching, managing and exploring the text data has become a main task. In this paper, we first represent an introduction to text mining and a probabilistic topic model Latent Dirichlet allocation. Then two experiments are proposed - Wikipedia articles and users’ tweets topic modelling. The former one builds up a document topic model, aiming to a topic perspective solution on searching, exploring and recommending articles. The latter one sets up a user topic model, providing a full research and analysis over Twitter users’ interest. The experiment process including data collecting, data pre-processing and model training is fully documented and commented. Further more, the conclusion and application of this paper could be a useful computation tool for social and business research.

  4. 15 CFR 296.33 - Annual report.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Annual report. 296.33 Section 296.33... Dissemination of Program Results § 296.33 Annual report. The Director shall submit annually to the Committee on... an evaluation of ongoing and completed awards. The first annual report shall include best...

  5. 25 CFR 122.9 - Annual report.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Annual report. 122.9 Section 122.9 Indians BUREAU OF... EDUCATION § 122.9 Annual report. The Osage Tribal Education Committee shall submit an annual report on OMB approved Form 1076-0106, Higher Education Annual Report, to the Assistant Secretary or his/her...

  6. 49 CFR 195.49 - Annual report.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Annual report. 195.49 Section 195.49... PIPELINE Annual, Accident, and Safety-Related Condition Reporting § 195.49 Annual report. Beginning no... dioxide pipelines. Operators are encouraged, but not required, to file an annual report by June 15,...

  7. 16 CFR 1018.42 - Annual report.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Annual report. 1018.42 Section 1018.42... Reports and Audits § 1018.42 Annual report. (a) The Advisory Committee Management Officer shall prepare an annual report on the Commission's advisory committees for inclusion in the President's annual report...

  8. Stockholder Reactions to Corporate Annual Reports.

    Science.gov (United States)

    Means, Thomas Lee

    A study was conducted to assess the extent to which (1) stockholders consider corporate annual reports to be informative and useful, (2) they actually read annual reports, (3) they consider annual reports to be impressive, and (4) they are motivated by the annual report to invest further in corporations in which they already own stock. After the…

  9. 77 FR 64463 - Annual Retail Trade Survey

    Science.gov (United States)

    2012-10-22

    ..., the Census Bureau will collect data covering annual sales, annual e- commerce sales, year-end..., accounts receivables, and, for selected industries, merchandise line sales, and percent of e-commerce sales..., annual sales, annual e-commerce sales, purchases, total and detailed operating expenses,...

  10. 75 FR 63804 - Annual Retail Trade Survey

    Science.gov (United States)

    2010-10-18

    ... survey, the Census Bureau will collect data covering annual sales, annual e-commerce sales, year-end... percent of e-commerce sales to customers located outside the United States. These data are collected to... classification basis, annual sales, annual e-commerce sales, purchases, total operating expenses,...

  11. NERI 2004 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    None

    2004-01-01

    The United States Department of Energy (DOE) created the Nuclear Energy Research Initiative (NERI) in Fiscal Year (FY) 1999 in response to recommendations provided by the President's Committee of Advisors on Science and Technology. The purpose of NERI is to sponsor research and development (R&D) in the nuclear energy sciences to address the principal barriers to the future use of nuclear energy in the United States. NERI is helping to preserve the nuclear science and engineering infrastructure within the Nation's universities, laboratories, and industry, and is advancing the development of nuclear energy technology, enabling the United States to maintain a competitive position in nuclear science and technology. Research under this initiative also addresses issues associated with the maintenance of existing U.S. nuclear plants. The NERI program is managed and funded by DOE's Office of Nuclear Energy, Science and Technology. ''The Nuclear Energy Research Initiative 2004 Annual Report'' serves to inform interested parties of progress made in NERI on a programmatic level as well as research progress made on individual NERI projects. Section 2 of this report provides background on the creation and implementation of NERI and on the focus areas for NERI research. Section 3 provides a discussion on NERI's mission, goals and objectives, and work scope. Section 4 highlights the major accomplishments of the NERI projects and provides brief summaries of the NERI research efforts that were completed in 2004. Section 5 provides a discussion on the impact NERI has had on U.S. university nuclear programs. Sections 6 through 8 provide project status reports by research area for each of the fiscal year (FY) 2001 and 2002 projects that were active in FY 2004. Research objectives, progress made over the last year, and activities planned for the next year are described for each project. Sections 9 through 11 present each of the newly awarded 2005

  12. Annual report 99

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    This volume of the Annual Report for the year 1999 provides the best illustration of this attempt: 30 highlights are presented covering a remarkable range of science and technique. As with last year's report, a wide spectrum of neutron science is embraced from biology, through to studies in chemistry, materials science and magnetism, to particle physics. To maintain this excellence, important efforts have been made in instrumentation; they are described in the technical section together with the Millennium Programme. This report is an appropriate illustration of the unique value of neutron methods for the study of a wide range of materials proving the usefulness of large-scale facilities such as the ILL. In 1999, the reactor operated for 208 days and more than 700 experiments were carried out in over 4400 days of scheduled beam time. Unfortunately, there was a failure of the hot source in December 1999 leading to a loss of about 20 days of beam time. Therefore, in 2000 the reactor will operate without the hot source. However, this will only affect 10 % of ILL's instruments. As in previous years, a large number of high-quality experiments was proposed and performed to tackle a broad range of scientific questions. For example in biology, the results presented here demonstrate that the contrast-variation method combined with small-angle scattering and neutron reflectivity techniques is a remarkable and unique tool for the investigation of biological materials. In the field of soft matter and liquids, it is known that confined geometry substantially modifies the properties of systems as diverse as simple water, polymers and quantum fluids. Neutron scattering experiments, presented here, have revealed the static and dynamic characteristics of these materials under conditions of confinement. In materials sciences, the penetration and contrast properties of neutrons are exploited, particularly in the case of small-angle scattering applied to alloys. Finally, the

  13. Conference Report: The BPS Annual Conference 2004

    Directory of Open Access Journals (Sweden)

    Irina Roncaglia

    2004-05-01

    Full Text Available In this article I will review four papers presented at the British Psychological Society Annual Conference held this year in London held over a 3 day period. The Conference included a variety of scientific presentations and discussions through symposia, roundtable discussions, single papers and poster sessions. Although numerous papers took an experimental approach, few applied any type of qualitative methodology. The topics covered within the different psychological disciplines spanned from early childhood through old age; I have chosen four papers that covered a life course perspective and took into consideration clinical issues as well. The first paper discusses a grounded theory approach used to analyse a play therapy session between therapist and child. The second review reports some recent findings in the way the brains of people on the autistic spectrum disorder might function. The third paper discusses positive psychology and how such an emerging movement has influenced new research in the field. The last paper reviewed will discuss the issue of the ageing process, and I will present some arguments related to the useful application of qualitative methodologies within this area of research. In conclusion, I will highlight some personal reflections on the Conference and the need for a greater balance between qualitative and quantitative methodologies to be used in collaboration rather than as antagonists. URN: urn:nbn:de:0114-fqs0402176

  14. ANSTO - Annual Report 1996-1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-09-01

    Highlights of achievements during 1996-1997 at the Australian Nuclear Science and technology (ANSTO) include: release of the new ANSTO Strategic Plan for the period till June 2000 and the establishment of a Technical Advisory Committee (TAC) of the Board. In accordance with the Strategic Plan, ANSTO has continued to focus its activities in six core business areas. The major outcomes and outputs of this work are outlined. The majority of ANSTO strategic research was directed at several topics launched during the year, including: international cooperative research to enhance safety of nuclear facilities and safeguards for nuclear materials, environmental dynamics, global climate change, radioactive waste management, ecological sustainability of the mining and mineral industries, radionuclides and radiopharmaceuticals for the 21st century and the design and process of novel interfaces. During the year major upgrades were made to he National Medical Cyclotron (NMC) and the Australian National Tandem Accelerator for Applied Research (ANTARES). The Annual Report documents the uses of these facilities by universities, industry, medicine and Government. Details are also provided of the organization development and support which support the core scientific areas. The financial statement for the year under review is also included tabs, ills, figs.

  15. New plan of strategy and organization. Annual report 1995; Ny strategisk plan og organisasjon. Aarsberetning 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-10-01

    The annual report from EFI (Norwegian Research Institute for Electricity) relates to an new strategic plan and organization of the institute. An example of this is the Research Council of Norway`s new R and D programme EFFEKT, which will be a major locomotive for research up to the year 2000. Topics are: EFI`s new strategic plan and organization; extracts from the Board`s annual report; extract from the accounts; diagnostic testing of circuit-breakers; breakdown and interruption statistics from the grid; power system reliability

  16. An analysis of topic areas and topic trends in the Community Mental Health Journal from 1965 through 1977.

    Science.gov (United States)

    Lounsbury, J W; Roisum, K G; Pokorny, L; Sills, A; Meissen, G J

    1979-01-01

    A content analysis of all (N = 604) published articles in the Community Mental Health Journal from 1965 through 1977 was performed (a) to provide a cross-sectional view of the community mental health field, and (b) to identify topic trends over time. Sixty-one content categories were used to classify topic areas. Results revealed major and growing emphases on organizing for the delivery and measuring of the effects of mental health service systems. Topics found to be increasing in relative frequency over time included training, measurement and research methodology, and intervention; those decreasing included planning and needs assessment, therapy, and suicide. Topic areas were compared with key characteristics of the field. Topic trends were interpreted in terms of open systems theory.

  17. Trends in biomedical informatics: automated topic analysis of JAMIA articles.

    Science.gov (United States)

    Han, Dong; Wang, Shuang; Jiang, Chao; Jiang, Xiaoqian; Kim, Hyeon-Eui; Sun, Jimeng; Ohno-Machado, Lucila

    2015-11-01

    Biomedical Informatics is a growing interdisciplinary field in which research topics and citation trends have been evolving rapidly in recent years. To analyze these data in a fast, reproducible manner, automation of certain processes is needed. JAMIA is a "generalist" journal for biomedical informatics. Its articles reflect the wide range of topics in informatics. In this study, we retrieved Medical Subject Headings (MeSH) terms and citations of JAMIA articles published between 2009 and 2014. We use tensors (i.e., multidimensional arrays) to represent the interaction among topics, time and citations, and applied tensor decomposition to automate the analysis. The trends represented by tensors were then carefully interpreted and the results were compared with previous findings based on manual topic analysis. A list of most cited JAMIA articles, their topics, and publication trends over recent years is presented. The analyses confirmed previous studies and showed that, from 2012 to 2014, the number of articles related to MeSH terms Methods, Organization & Administration, and Algorithms increased significantly both in number of publications and citations. Citation trends varied widely by topic, with Natural Language Processing having a large number of citations in particular years, and Medical Record Systems, Computerized remaining a very popular topic in all years.

  18. Periorbital muscle atrophy associated with topical bimatoprost therapy

    Directory of Open Access Journals (Sweden)

    Wang PX

    2014-01-01

    Full Text Available Priscilla Xinhui Wang, Victor Teck Chang Koh, Jin Fong ChengDepartment of Ophthalmology, National University Health System, SingaporeAbstract: Topical Bimatoprost is a common and popular prostaglandin analog used as an ocular hypotensive agent in the treatment of glaucoma. Side effects include ocular hyperaemia, ocular pruritus, and periocular and iris pigmentary changes. Perioribital lipodystrophy is another well-documented outcome associated with chronic use of topical bimatoprost, which results in periorbital hallowing, upper eyelid sulcus deepening, eyelid retraction and enophthalmos. We report an unusual case of periocular muscle atrophy and weakness from unilateral topical bimatoprost use. Our patient had primary angle closure and experienced a right upper eyelid ptosis 2 months after she started to use topical bimatoprost in that eye. Clinical measurements of her eyelids clearly showed reduction in the function of her right levator muscle, suggesting that effects of topical bimatoprost may not be limited to periorbital fat. She was advised to stop topical bimatoprost and right ptosis correction surgery with levator muscle advancement was performed successfully. Ophthalmologists and patients should be aware of this potential rare side effect of topical bimatoprost, as it may be potentially disfiguring, especially with monocular use. However, its exact mechanism of action needs to be clarified further.Keywords: prostaglandin analog, levator, muscle atrophy, muscle weakness, ptosis, side effects

  19. A method of detecting emerging trends in research topics

    Institute of Scientific and Technical Information of China (English)

    Fei; GE; Zongying; TAN

    2014-01-01

    Purpose:This paper proposes a method of detecting emerging trends in research topics from a more micro perspective.Design/methodology/approach:Through co-word clustering to identify research topics and analyzing position changes of topic words in the keywords life-cycle diagram during different time periods,we detected emerging trends in research topics from a more micro perspective.I’he method was applied to the field of nanotechnology to verify its effectiveness and practicability.Findings:The results show that this method can be used to detect emerging trends in research topics from a more micro perspective,as it divides keywords into five categories:Potential keywords,emerging keywords,hot keywords,stable keywords and recession keywords,through which more details of topic changes can be found.Research limitations:We used keywords provided by authors and database indexers for keywords extraction.But this approach may lead to the problem of "indexer effect".The method may have a limited effect when applied to a disciplinary domain such as mathematics,which evolves slowly.Practical implications:This study provides information analysts with insights into the way to better understand specialty areas of a discipline domain and formulate research policies and strategic plans.Originality/value:This study contributes to the current literature by proposing a new method,which can detect emerging trends in research topics from a more micro perspective.

  20. Longitudinal Studies of the Effects and Costs of Early Intervention for Handicapped Children. Annual Report 1987-88.

    Science.gov (United States)

    Utah State Univ., Logan. Early Intervention Research Inst.

    The 1987-88 annual report reviews progress on 17 longitudinal studies to determine the efficacy of early intervention with handicapped children. The overview chapter reviews previous research on this topic; considers ethical, practical, and scientific considerations of randomized experiments in early childhood special education; examines benefits…

  1. Proceedings of the 1982 Annual Meeting. Canadian Mathematics Education Study Group (Queen's University, Kingston, Ontario, June 3-7, 1982).

    Science.gov (United States)

    Drost, Dale R., Ed.

    Papers from the 1982 annual meeting of the Canadian Mathematics Education Study Group are organized similarly to the meeting, presenting materials from the lectures, working groups, topic groups and panel groups. One lecture, by Davis, discussed a philosophy of computation in relation to computing. Vergnaud lectured on cognitive and developmental…

  2. Annual report - Industrias Nucleares do Brasil S A - 1998; Relatorio anual - Industrias Nucleares do Brasil S A - 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    The annual report of 1998 of Industrias Nucleares do Brasil S A - Brazilian company responsible for the industrial activities of the nuclear fuel cycle - introduces the next main topics: mineral resource directory main actions; industrial directory main actions; finance and administration directory main actions; transparency; environment, safety and quality; the company; and financial statements.

  3. INTRODUCTION TO TOPIC "TOWARDS THE LEGAL RECOGNITION AND GOVERNANCE OF ECOSYSTEM SERVICES"

    Directory of Open Access Journals (Sweden)

    A Iza

    2013-06-01

    Full Text Available On behalf of the IUCN Environmental Law Centre, the IUCN Academy of Environmental Law and the IUCN Commission on Environmental Law, I would like to introduce you to the topic of this Journal "Towards the legal recognition and governance of ecosystem services." First of all, I would like to thank the Co-Chairs of the Academy´s Research Committee and the Deputy Chair of the IUCN Commission on Environmental Law for this initiative and I am most happy to see that, throughout its organisation, collaboration between the three organisations has continued to grow. We organised our first joint-workshop in 2011 in Ghent, Belgium, just before the IUCN Academy´s 8th annual colloquium. The feeling that we all had as the successful event came to an end, was that this collaboration should be repeated on an annual basis. The 2011 Mpekweni Workshop revolved around legal frameworks for the recognition and governance of ecosystem services. Maintaining healthy ecosystems and the continuing provision of services such as water supply or climate regulation is key to ensuring present and future human livelihoods, the fulfillment of the Millennium Development Goals and for any form of poverty alleviation strategy.

  4. A review of Technologies on Tracking Tibetan Public Opinion Topics

    Directory of Open Access Journals (Sweden)

    Chen Bi-Rong

    2016-01-01

    Full Text Available The target of technologies on tracking Tibetan-based network public opinion topics is to track the development of some known topics. By tracking these topics could help people to grasp the trend of public opinion. This research area becomes more and more important on Natural Language Processing domain and how to apply these state-of-the-art computer science technologies on the study of national language has drawn lots of awareness to related researchers. This article will introduce some features about Tibetan language and its grammar. Some technologies about categorizing Tibetan text and tracking Tibetan-based network public opinion will also be talked about.

  5. Convergence of Influential Bloggers for Topic Discovery in the Blogosphere

    Science.gov (United States)

    Kumar, Shamanth; Zafarani, Reza; Abbasi, Mohammad Ali; Barbier, Geoffrey; Liu, Huan

    In this paper, we propose a novel approach to automatically detect "hot" or important topics of discussion in the blogosphere. The proposed approach is based on analyzing the activity of influential bloggers to determine specific points in time when there is a convergence amongst the influential bloggers in terms of their topic of discussion. The tool BlogTrackers, is used to identify influential bloggers and the Normalized Google Distance is used to define the similarity amongst the topics of discussion of influential bloggers. The key advantage of the proposed approach is its ability to automatically detect events which are important in the blogger community.

  6. High death rate in mice treated topically with diclofenac

    DEFF Research Database (Denmark)

    Lerche, Catharina M; Philipsen, Peter A; Poulsen, Thomas

    2011-01-01

    Recently, 3% diclofenacnatrium gel (diclofenac) was introduced for the treatment of actinic keratoses. Data on photocarcinogenesis of topical diclofenac are limited, and we wished to investigate whether topical diclofenac can accelerate photocarcinogenesis using simulated solar radiation (SSR......). Diclofenac was applied topically on the backs of hairless, female, C3.Cg/TifBomTac immunocompetent mice three times weekly followed by ultraviolet radiation (2, 3, or 4 Standard Erythema Dose) until death. There was a significant difference in survival between diclofenac-treated groups and control groups (P...

  7. Review of topical beta blockers as treatment for infantile hemangiomas.

    Science.gov (United States)

    Painter, Sally L; Hildebrand, Göran Darius

    2016-01-01

    The treatment of infantile hemangiomas changed from the use of oral corticosteroids to oral propranolol on the serendipitous discovery of propanolol's clinical effectiveness in 2008. Since then, clinicians have begun to use topical beta blockers--in particular, timolol maleate 0.5% gel forming solution--with good effect. Topical beta blockers are now used for lesions with both deep and superficial components and those that are amblyogenic. When initiated in the proliferative phase of the lesion, the effectiveness of the treatment can be seen within days. There is no consensus on dosing, treatment bioavailability, or clinical assessment of lesions, but these are topics for future research.

  8. Intolerance to topical products may be due to dermographism.

    Science.gov (United States)

    Watsky, Kalman L; McGovern, Thomas

    2003-03-01

    Patients with reactions to topical products may be eliciting a physical urticaria, dermographism, by rubbing. These reactions may be misinterpreted as allergic, and three cases demonstrating this phenomenon were reviewed. All patients with reactions to topical products due to dermographism improved with counseling and antihistamine therapy. Repeat open application testing confirmed the safety of previously suspect medications in two of the three cases, preventing unnecessary changes in the medication regimens and inaccurate diagnoses of medication allergy. We observe that intolerance to topical medications due to dermographism can usually be managed without extensive testing or treatment.

  9. Engineering Annual Summary 1998

    Energy Technology Data Exchange (ETDEWEB)

    Dimolitsas, S

    1999-05-01

    Unlike most research and development laboratories, Lawrence Livermore National Laboratory (LLNL) is responsible for delivering production-ready designs. Unlike most industry, LLNL is responsible for R and D that must significantly increase the nation's security. This rare combination of production engineering expertise and national R and D agenda identifies LLNL as one of the few organizations today that conducts cutting-edge engineering on grand-scale problems, while facing enormous technical risk and undergoing diligent scrutiny of its budget, schedule, and performance. On the grand scale, cutting-edge technologies are emerging from our recent ventures into ''Xtreme Engineering{trademark}.'' Basically, we must integrate and extend technologies concurrently and then push them to their extreme, such as building very large structures but aligning them with extreme precision. As we extend these technologies, we push the boundaries of engineering capabilities at both poles: microscale and ultrascale. Today, in the ultrascale realm, we are building NIF, the world's largest laser, which demands one of the world's most complex operating systems with 9000 motors integrated through over 500 computers to control 60,000 points for every laser shot. On the other pole, we have fabricated the world's smallest surgical tools and the smallest instruments for detecting biological and chemical agents used by antiterrorists. Later in this Annual Summary, we highlight some of our recent innovations in the area of Xtreme Engineering, including large-scale computer simulations of massive structures such as major bridges to prepare retrofitting designs to withstand earthquakes. Another feature is our conceptual breakthrough in developing the world's fastest airplane, HyperSoar, which can reach anywhere in the planet in two hours at speeds of 6700 mph. In the last few years, Engineering has significantly pushed the technology in structural

  10. Annual fish: developmental adaptations for an extreme environment.

    Science.gov (United States)

    Berois, Nibia; Arezo, María J; Papa, Nicolás G; Clivio, Graciela A

    2012-01-01

    Annual fish are freshwater teleosts found in South America and Africa that are exposed to an extremely variable environment. They develop and reproduce in seasonal ponds that dry during the summer eliminating the entire adult population. Remarkably, desiccation-resistant embryos survive in these dry ponds that hatch during the next rainy season when the ponds are recreated. Among vertebrates, they represent one of the most remarkable extremophiles. They share several features with other fish models; however, they exhibit unique traits related to their peculiar life cycle. Epiboly is temporally and spatially uncoupled from organogenesis, and the embryos can undergo reversible developmental arrests (diapauses). These attributes make them a useful model to study diverse topics in developmental biology using a comparative and evolutionary approach. In this article, different aspects related to annual fish biology, taxonomy and phylogenetic considerations, reproductive strategy, and developmental characteristics with special focus on arrests, are summarized. The current challenge is to document and determine the factors that generate such high diversity and unique adaptations of annual fish. To understand this complexity, interdisciplinary approaches are being employed taking into consideration evolutionary biology, ethology, reproductive strategies, regulation of developmental mechanisms, and senescence.

  11. Dose verification after topical treatment of alligator (Alligator mississippiensis) eggs.

    Science.gov (United States)

    Muller, Jennifer K; Scarborough, Janet E; Sepúlveda, María S; Casella, George; Gross, Timothy S; Borgert, Christopher J

    2007-05-01

    Numerous studies have used temperature-dependent sex determination in reptilian eggs to investigate potential developmental effects of exogenously applied substances. However, few studies have measured the dose carried across the eggshell. We report embryonic mortality and internal egg concentrations determined by gas chromatography-mass spectrometry two weeks after exposure of American alligator (Alligator mississippiensis) eggs to chlorinated organic pesticides via injection or topical application. Puncturing the eggshell for injection produced high mortality compared with unpunctured controls; therefore, further evaluation of this method was abandoned. Although higher than controls, mortality was much lower in eggs treated topically than in those injected. Transfer of chemicals across the eggshell was very low, highly variable, and did not correlate with the applied dose after topical application. These results are consistent with previous reports in the literature, casting doubt on whether a reproducible internal dose can be achieved in reptilian eggs by topical treatment.

  12. A topic evolution model with sentiment and selective attention

    Science.gov (United States)

    Si, Xia-Meng; Wang, Wen-Dong; Zhai, Chun-Qing; Ma, Yan

    2017-04-01

    Topic evolution is a hybrid dynamics of information propagation and opinion interaction. The dynamics of opinion interaction is inherently interwoven with the dynamics of information propagation in the network, owing to the bidirectional influences between interaction and diffusion. The degree of sentiment determines if the topic can continue to spread from this node, and the selective attention determines the information flow direction and communicatee selection. For this end, we put forward a sentiment-based mixed dynamics model with selective attention, and applied the Bayesian updating rules on it. Our model can indirectly describe the isolated users who seem isolated from a topic due to some reasons even everybody around them has heard about it. Numerical simulations show that, more insiders initially and fewer simultaneous spreaders can lessen the extremism. To promote the topic diffusion or restrain the prevailing of extremism, fewer agents with constructive motivation and more agents with no involving motivation are encouraged.

  13. HIV/AIDS Medicines: MedlinePlus Health Topic

    Science.gov (United States)

    ... Infectious Diseases) Children Approved Antiretroviral Drugs Used for Pediatric Treatment of HIV Infection (Food and Drug Administration) Patient Handouts FDA-Approved HIV Medicines (AIDSinfo) Also in Spanish Topic Image MedlinePlus Email Updates Get HIV/AIDS ...

  14. Integrating ethical topics in a traditional computer science course

    Energy Technology Data Exchange (ETDEWEB)

    Winrich, L.B. [Univ. of North Dakota, Grand Forks, ND (United States)

    1994-12-31

    It is never hard to find additional, often unconventional, topics which seem to beg inclusion in standard courses. A dynamic discipline like computer science usually provides a steady stream of new technical ideas to vie for time and attention with more traditional material. As difficult as it may be to keep standard CS courses up-to-date with technical innovations, it often seems even more difficult to include non-technical topics even when there is universal agreement on their importance, Inevitably the question of whether or not such inclusion will compromise the technical content of the course arises. This paper describes an attempt to include two such topics in a traditional course in data structures. The two topics are writing and ethics and, although the effort concentrates on the inclusion of ethical questions in a standard CS course, writing is the vehicle for accomplishing this goal. Furthermore, the inclusion writing in the CS curriculum is certainly recognized as a desirable outcome.

  15. Worldwide Utilization of Topical Remedies in Treatment of Psoriasis

    DEFF Research Database (Denmark)

    Svendsen, Mathias Tiedemann; Jeyabalan, Janithika; Andersen, Klaus Ejner;

    2016-01-01

    of topical antipsoriatics, using six different methods to collect data. The eight most frequently used topical treatments from the regions North/South America, North/Central/South Europe, Asia, Middle East, and Australia were: corticosteroids used by 16-79%, complementary and alternative medicines used by 10...... professionals involvement of the patient with respect to choosing prescribed topical treatment and the possibility of patients' use of alternative treatments. More drug utilization studies, both survey and register-based, from different parts of the world are needed to provide more conclusive evidence about......OBJECTIVE: To review published literature describing the global use of topical antipsoriatics. MATERIAL AND METHODS: Search for English-language articles in Embase, Pubmed, PsycINFO, and Cochrane Library. RESULTS: Fifty-four selected publications were found, describing psoriasis patients' use...

  16. Topical ethosomal capsaicin attenuates edema and nociception in arthritic rats.

    Science.gov (United States)

    Kumar Sarwa, Khomendra; Rudrapal, Mithun; Mazumder, Bhaskar

    2015-12-01

    In this study, topical ethosomal formulation of capsaicin was prepared and evaluated for bio-efficacy in arthritic rats. Physical and biological characterizations of prepared capsaicin-loaded nano vesicular systems were also carried out. Ethosomal capsaicin showed significant reduction of rat paw edema along with promising antinociceptive action. The topical antiarthritic efficacy of prepared formulation of capsaicin was found more than that of Thermagel, a marketed gel of capsaicin. From toxicological study, no predictable signs of toxicity such as skin irritation (of experimental rats) were observed. Based on this finding, ethosomal capsaicin could be proposed as an effective as well as a safe topical delivery system for the long-term treatment of arthritis and associated inflammo-musculoskeletal disorders. Such exciting result would eventually enlighten the analgesic and anti-inflammatory potential of capsaicin for topical remedy.

  17. Recombinant DNA Technology. A Topics Course for Undergraduates.

    Science.gov (United States)

    Parson, Kathleen A.

    1988-01-01

    Describes the development of a topics course offered jointly by the chemistry and biology departments at Macalester College (Minnesota). Outlines the syllabus for the course. Discusses teaching and laboratory methods used. (CW)

  18. Topical NSAIDs for acute pain: a meta-analysis

    Directory of Open Access Journals (Sweden)

    Derry Sheena

    2004-05-01

    Full Text Available Abstract Background A previous systematic review reported that topical NSAIDs were effective in relieving pain in acute conditions like sprains and strains, with differences between individual drugs for efficacy. More trials, a better understanding of trial quality and bias, and a reclassification of certain drugs necessitate a new review. Methods Studies were identified by searching electronic databases and writing to manufacturers. We selected randomised double blind trials comparing topical NSAID with either placebo or another active treatment in adults with acute pain, and extracted dichotomous information approximating to a 50% reduction in pain at one week, together with details of adverse events and withdrawals. Relative benefit and number-needed-to-treat (NNT, and relative risk and number-needed-to-harm (NNH were calculated, with sensitivity analyses where appropriate to investigate differences between individual drugs and aspects of trial design. Results Twenty-six double blind placebo controlled trials had information from 2,853 patients for evaluation of efficacy. Topical NSAID was significantly better than placebo in 19 of the 26 trials, with a pooled relative benefit of 1.6 (95% confidence interval 1.4 to 1.7, and NNT of 3.8 (95% confidence interval 3.4 to 4.4 compared with placebo for the outcome of half pain relief at seven days. Results were not affected by outcome reported, or condition treated, but smaller trials yielded a larger estimate of efficacy. Indirect comparisons of individual topical NSAIDs showed that ketoprofen was significantly better than all other topical NSAIDs, while indomethacin was barely distinguished from placebo. Three trials, with 433 patients, compared topical with oral NSAID (two trials compared the same drug, one compared different drugs and found no difference in efficacy. Local adverse events, systemic adverse events, or withdrawals due to an adverse event were rare, and no different between topical

  19. Successful salvage treatment of Lecythophora mutabilis keratitis with topical voriconazole

    Directory of Open Access Journals (Sweden)

    Bora Yüksel

    2011-09-01

    Full Text Available Fungal keratitis is an important ophthalmic problem in the developing world. Filamentous fungi are the most frequently reported pathogens in fungal keratitis. This report aimed to present a case with Lecythophora mutabilis keratitis that treatment failure was seen with topical and systemic amphotericin B lipid complex. Then she was treated successfully topical voriconazole. J Microbiol Infect Dis 2011;1 (2: 75-77

  20. Topic Modeling Based Image Clustering by Events in Social Media

    OpenAIRE

    2016-01-01

    Social event detection in large photo collections is very challenging and multimodal clustering is an effective methodology to deal with the problem. Geographic information is important in event detection. This paper proposed a topic model based approach to estimate the missing geographic information for photos. The approach utilizes a supervised multimodal topic model to estimate the joint distribution of time, geographic, content, and attached textual information. Then we annotate the missi...